WorldWideScience

Sample records for eccs

  1. Extrusion of ECC-Material

    DEFF Research Database (Denmark)

    Stang, Henrik; Li, Victor C.

    1999-01-01

    in recent years at Department of Civil and Envirionmetal Engineering, University of Michigan. These materials have been developed with the special aim of producing high performance , strain hardening materials with low volume concentrations of short fibers in a cementitious material.ECC material spcimens...... have until now been produced by traditional casting processes. In the present paper results from a recent collaborative reserach project are documented - demonstrating that ECC materials can be extruded in the process referred to above.......An extrusion process especially designed for extrusion of pipes made from fiber reinforced cementitious materials has been developed at Department of Structural Engineering and Materials at the Technical University of DenmarkEngineered Cementitious Composite (ECC) materials have been developed...

  2. ECCS flow verification to support transient analysis

    Energy Technology Data Exchange (ETDEWEB)

    Kovach, C.; Jacobs, R.H.; Ballard, J.E. [Commonwealth Edison Co., Chicago, IL (United States). Nuclear Fuel Services Dept.

    1994-12-31

    The RETRAN code has been used to develop a model of the Emergency Core Cooling System (ECCS). The model was developed in order to provide conservative injection flow data to be used in various LOCA and non-LOCA analyses and evaluations and to ensure that ECCS pump runout does not occur. The analyses were also needed in order to address a number of ECCS performance issues identified by Westinghouse. These issues include how previous analyses modeled miniflow, RCP seal injection, ECCS branch line resistance, pump suction boost during recirculation, injection line flow imbalances, and, of particular importance, ECCS flow measurement inaccuracies. In turn, these issues directly impact pump runout concerns, Technical Specification verification, and ECCS injection flow during transient conditions. The RETRAN ECCS model has proven to be quite versatile, easy to use, and requires only minimal information about the physical construction and performance of the ECCS system.

  3. ECCE 41. konverents Tallinnas / Urmo Kala

    Index Scriptorium Estoniae

    Kala, Urmo

    2005-01-01

    9.-11. juunini 2005. a. toimus Tallinnas Eesti Ehitusinseneride Liidu korraldusel Euroopa ehitusinseneride liitude ühenduse (ECCE) 41. konverents. ECCE on nõuandvaks organiks Euroopa Liidu struktuuridele ja liikmesriikide valitsustele ehituspoliitika, ehitusstandardite, ehitusalase hariduse, ehituse ohutuse ja kvaliteedinõuete väljatöötamisel

  4. ECC Ozonesonde Calibration and Observations: Satellite Validation

    Science.gov (United States)

    Schmidlin, Francis J.; Zukor, Dorothy (Technical Monitor)

    2001-01-01

    The reliability of the Electrochemical Concentration Cell (ECC) ozonesonde depends on the care exercised in preparing the instrument for use. Although the ECC can be quickly prepared and flown, generally within less then one day if necessary, it is best to prepare the instrument at least one week prior to use, and as our tests have confirmed even 2-3 weeks prior to use may actually be better. There are a number of factors that must be considered when preparing an ECC. These basically are the pump efficiency, volumetric flow rate, temperature of the air entering the pump, and the background current. Also of importance is the concentration of the potassium iodide solution. Tests conducted at Wallops Island (38 N) has enabled us to identify potential problem areas and ways to avoid them. The calibration and pre-flight preparation methods will be discussed. The method of calibrating the ECC also is used at Ascension Island (8 S) and Natal, Brazil (5 S). Comparisons between vertical profiles of the ECC instrument and satellites will be reviewed as well as comparison with ground based instruments, such as, the Dobson Spectrophotometer and hand held Microtops photometers.

  5. Attacks and countermeasures on AES and ECC

    DEFF Research Database (Denmark)

    Tange, Henrik; Andersen, Birger

    2013-01-01

    AES (Advanced Encryption Standard) is widely used in LTE and Wi-Fi communication systems. AES has recently been exposed to new attacks which have questioned the overall security of AES. The newest attack is a so called biclique attack, which is using the fact that the content of the state array...... side-channels attacks can be applied to ECC. This paper reflects an ongoing research in the field of countermeasures against the attacks mentioned above....

  6. Noise-based Stego-ECC

    Directory of Open Access Journals (Sweden)

    Rahardjo Budi

    2014-03-01

    Full Text Available A novel method of inserting noise into stream of ciphered text is proposed. The goal of inserting noise is to increase the level of uncertainty, thus making it harder for an attacker to detect data and noise. This form of steganography is implemented using Elliptic Curve Cryptography (ECC. The process of embedding the noise to the message in the encryption process and removing the noise from the message in the decryption process is proposed in this work by modifying ElGamal to allow auto detection of data and noise.

  7. ECC over RSA for Asymmetric Encryption-A Review

    Directory of Open Access Journals (Sweden)

    Kamlesh Gupta

    2011-05-01

    Full Text Available Cryptography is used to transmit the data securely in open network. This paper gives the survey of Elliptic Curve Cryptosystem (ECC used in many applications. ECC is a when compared to RSA and discrete logarithm systems, is a better option for the future. For this reason ECC is such an excellent choice for doing asymmetric cryptography in portable devices right now. The smaller ECC keys it turn makes the cryptographic operations that must be performed by the communicating devices to be embedded into considerably smaller hardware, so that software applications may complete cryptographic operations with fewer processor cycles, and operations can be performed much faster, while still retaining equivalent security. This means, in turn, reduced power consumption, less space consumed on the printed circuit board, and software applications that run more rapidly make lower memory demands. In brief, for communication using smaller devices and asymmetric cryptosystem we need ECC.

  8. ECCE Toolkit: Prototyping Sensor-Based Interaction

    Science.gov (United States)

    Bellucci, Andrea; Aedo, Ignacio; Díaz, Paloma

    2017-01-01

    Building and exploring physical user interfaces requires high technical skills and hours of specialized work. The behavior of multiple devices with heterogeneous input/output channels and connectivity has to be programmed in a context where not only the software interface matters, but also the hardware components are critical (e.g., sensors and actuators). Prototyping physical interaction is hindered by the challenges of: (1) programming interactions among physical sensors/actuators and digital interfaces; (2) implementing functionality for different platforms in different programming languages; and (3) building custom electronic-incorporated objects. We present ECCE (Entities, Components, Couplings and Ecosystems), a toolkit for non-programmers that copes with these issues by abstracting from low-level implementations, thus lowering the complexity of prototyping small-scale, sensor-based physical interfaces to support the design process. A user evaluation provides insights and use cases of the kind of applications that can be developed with the toolkit. PMID:28241502

  9. An ECC-Based Blind Signature Scheme

    Directory of Open Access Journals (Sweden)

    Fuh-Gwo Jeng

    2010-08-01

    Full Text Available Cryptography is increasingly applied to the E-commerce world, especially to the untraceable payment system and the electronic voting system. Protocols for these systems strongly require the anonymous digital signature property, and thus a blind signature strategy is the answer to it. Chaum stated that every blind signature protocol should hold two fundamental properties, blindness and intractableness. All blind signature schemes proposed previously almost are based on the integer factorization problems, discrete logarithm problems, or the quadratic residues, which are shown by Lee et al. that none of the schemes is able to meet the two fundamental properties above. Therefore, an ECC-based blind signature scheme that possesses both the above properties is proposed in this paper.

  10. ECCE Toolkit: Prototyping Sensor-Based Interaction.

    Science.gov (United States)

    Bellucci, Andrea; Aedo, Ignacio; Díaz, Paloma

    2017-02-23

    Building and exploring physical user interfaces requires high technical skills and hours of specialized work. The behavior of multiple devices with heterogeneous input/output channels and connectivity has to be programmed in a context where not only the software interface matters, but also the hardware components are critical (e.g., sensors and actuators). Prototyping physical interaction is hindered by the challenges of: (1) programming interactions among physical sensors/actuators and digital interfaces; (2) implementing functionality for different platforms in different programming languages; and (3) building custom electronic-incorporated objects. We present ECCE (Entities, Components, Couplings and Ecosystems), a toolkit for non-programmers that copes with these issues by abstracting from low-level implementations, thus lowering the complexity of prototyping small-scale, sensor-based physical interfaces to support the design process. A user evaluation provides insights and use cases of the kind of applications that can be developed with the toolkit.

  11. ECCE Toolkit: Prototyping Sensor-Based Interaction

    Directory of Open Access Journals (Sweden)

    Andrea Bellucci

    2017-02-01

    Full Text Available Building and exploring physical user interfaces requires high technical skills and hours of specialized work. The behavior of multiple devices with heterogeneous input/output channels and connectivity has to be programmed in a context where not only the software interface matters, but also the hardware components are critical (e.g., sensors and actuators. Prototyping physical interaction is hindered by the challenges of: (1 programming interactions among physical sensors/actuators and digital interfaces; (2 implementing functionality for different platforms in different programming languages; and (3 building custom electronic-incorporated objects. We present ECCE (Entities, Components, Couplings and Ecosystems, a toolkit for non-programmers that copes with these issues by abstracting from low-level implementations, thus lowering the complexity of prototyping small-scale, sensor-based physical interfaces to support the design process. A user evaluation provides insights and use cases of the kind of applications that can be developed with the toolkit.

  12. Condensation during gravity driven ECC: Experiments with PACTEL

    Energy Technology Data Exchange (ETDEWEB)

    Munther, R.; Kalli, H. [Lappeenranta Univ. of Technology (Finland); Kouhia, J. [Technical Research Centre of Finland, Lappeenranta (Finland)

    1995-09-01

    This paper provides the results of the second series of gravity driven emergency core cooling (ECC) experiments with PACTEL (Parallel Channel Test Loop). The simulated accident was a small break loss-of-coolant accident (SBLOCA) with a break in a cold leg. The ECC flow was provided from a core makeup tank (CMT) located at a higher elevation than the main part of the primary system. The CMT was pressurized with pipings from the pressurizer and a cold leg. The tests indicated that steam condensation in the CMT can prevent ECC and lead to core uncovery.

  13. Shear behavior of reinforced Engineered Cementitious Composites (ECC) beams

    DEFF Research Database (Denmark)

    Paegle, Ieva; Fischer, Gregor

    2010-01-01

    This paper describes an experimental investigation of the shear behavior of beams consisting of steel reinforced Engineered Cementitious Composites (ECC). Based on the strain hardening and multiple cracking behavior of ECC, this study investigates the extent to which ECC can improve the shear...... randomly distributed PVA (polyvinyl alcohol) fiber beams with different stirrup spacing and reinforced concrete (RC) beams for comparison. Displacement and strain measurements taken using the ARAMIS photogrammetric data acquisition system by means of processing at high frame rate captured images of applied...

  14. [Patient's pain feeling and surgeon's comfort--ECCE versus phacoemulsification].

    Science.gov (United States)

    Kałuzny, Jakub J; Eliks, Iwona; Mierzejewski, Andrzej; Kałuzny, Bartłomiej

    2004-01-01

    To compare patient's pain and surgeon's comfort during ECCE performed under retrobulbar anesthesia and phacoemulsification under topical anesthesia. 120 patients scheduled for planned routine cataract extraction were divided in 2 groups: group 1-60 eyes, ECCE under retrobulbar anesthesia and group II-60 eyes, phacoemulsification under topical anesthesia. Immediately after operation patients were asked, to answer questions about their feeling during surgery. Simultaneously, the surgeon filled up the questionnaire, concerning patients behavior during the entire procedure. Statistically significant higher level of pain was reported in group I (ECCE). The most painful moment of the procedure was retrobulbar injection. During surgery pain feeling in both groups was similar. Both types of anesthesia provided very good level of surgeon's comfort. The longer operation, the higher level of pain and lower surgeon's comfort were reported in both groups. Patients having ECCE performed under retrobulbar anesthesia reported more pain comparing to phacoemulsification under topical anesthesia. Both anesthesia methods provided high level of surgeon's comfort.

  15. Present soil data for the ECCES-program system. [ECCES - Environmental Calculations of Consequences of Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Mortensen, P.B.

    1986-01-01

    This is a status report that presents area and soil data, soil characteristics and input data used in the ECCES-program system for Danish arable soils. Input of ions to the upper soil layer with rain, fertilizer and lime are described together with the parameters used to describe the properties of different soil types. Together with a series of other reports, this report forms part of the description of the ECCES-model developed at Risoe National Laboratory.

  16. Application of Engineered Cementitious Composites (ECC) in modular floor panels

    DEFF Research Database (Denmark)

    Lárusson, Lárus Helgi; Fischer, Gregor; Jönsson, Jeppe

    2008-01-01

    This paper describes the design, manufacturing, and structural behavior of a prefabricated floor panel consisting of a modular assembly of a thin-walled ECC slab and steel truss girders. The features of this composite structure include light weight, the modular manufacturing process...... with adaptability to various loading requirements, and the efficient utilization of material resources and industrial byproducts. The work described in this paper is a continuation of previous activities on composite floor panels in which light gage steel joists were integrally cast with the ECC slab. The modular...... concept introduced in this paper aims at improvements in the manufacturing process of the panels by casting the ECC slab separately and subsequently joining it with the steel trusses. The focus of this paper is on design and manufacturing of a prototype modular panel and on its structural behavior under...

  17. Visual outcomes after anterior vitrectomy: comparison of ECCE and phacoemulsification.

    Science.gov (United States)

    Bobrow, J C

    1999-01-01

    To determine whether vitrectomy instrumentation improved outcomes when vitreous loss occurred during either extracapsular cataract extraction (ECCE) or phacoemulsification (PE) with posterior chamber lens implantation (PCIOL). A consecutive series of ECCE + PCIOL (group 1: 1985-1989) and PE + PCIOL (group 2: 1993-1997) surgeries by a single surgeon was reviewed retrospectively. In group 1, 14 of 647 patients (2.2%) and in group 2, 9 of 665 patients (1.4%) experienced vitreous loss. In group 1, final visual acuity averaged 20/83; in group 2, 20/25 (P = .005). Average follow-up was 5.7 years (group 1) and 3.2 years (group 2). Uveitis, glaucoma, corneal problems, and retinal problems were assessed. Anterior vitrectomy reduced complications from vitreous loss. Fewer vitreous losses occurred with PE than ECCE. Patients with vitreous loss after PE attained better vision.

  18. Intraocular pressure following ECCE, phacoemulsification, and PC-IOL implantation.

    Science.gov (United States)

    Kooner, K S; Cooksey, J C; Perry, P; Zimmerman, T J

    1988-09-01

    Abnormal intraocular pressure (IOP), either transient or permanent, may follow extracapsular cataract extraction (ECCE) with phacoemulsification (PE) and posterior chamber intraocular lens (PC-IOL) implantation. We retrospectively studied IOP measurements at different intervals post ECCE and PE in 242 eyes of 211 patients: 105 males, 106 females, 198 Caucasians and 13 blacks. Elevated IOP (greater than 23 mm Hg) was observed in 20 eyes (8.2%). Only two patients (0.8%) had persistent (greater than 3 months) IOP elevation and needed antiglaucoma therapy. Six more eyes (2.5%), however, developed glaucoma after 1 year. Hence, the incidence of secondary pseudophakic glaucoma at the conclusion of this study was 3.3%. No patient required laser or other mechanical surgery for IOP control. ECCE and PE with PC-IOL does not appear to adversely affect IOP. Patients, however, must be followed closely, as some may develop glaucoma months after surgery.

  19. Modeling of ECC materials using numerical formulations based on plasticity

    DEFF Research Database (Denmark)

    Dick-Nielsen, Lars; Stang, Henrik; Poulsen, Peter Noe

    2006-01-01

    This paper discusses the considerations for the establishment of a damage model for ECC. Three different length scales are used in the approach for deriving the damage model. On each length scale important phenomena are investigated by use of numerical and analytical calculations. On the micro...... scale it is shown that the cohesive law for a unidirectional fiber reinforced cementitious composite can be found through superposition of the cohesive law for mortar and the fiber bridging curve. On the meso scale I it is shown that the maximum crack opening observed during crack propagation in ECC...

  20. Ecce homo, a fisio-psicologia de um tipo

    OpenAIRE

    2007-01-01

    No presente estudo, pretendemos realizar uma leitura de Ecce homo balizada pelo procedimento genealógico, pela fisio-psicologia e pela tipologia presentes no pensamento de Nietzsche. Acreditamos que a mudança que se opera no tratamento do humano a partir dessas três noções permite a Nietzsche, em Ecce homo, realizar uma espécie de duplo movimento. Por um lado, o filósofo realiza a máxima afirmação da vida e de si mesmo, dando expressão a uma série de estados afetivos que o constitui. Por outr...

  1. Un Ecce Homo de Antonio del Castillo en Granada

    Directory of Open Access Journals (Sweden)

    Montes González, Francisco

    2012-03-01

    Full Text Available The author presents a previously unknown painting by the Baroque artist from Cordoba, Antonio del Castillo y Saavedra. It is an Ecce Homo, a late work, and located in a private collection in Granada.Este artículo presenta el último aporte en el catálogo del pintor barroco cordobés Antonio del Castillo y Saavedra. Se trata de un lienzo con la iconografía del Ecce Homo, perteneciente a su última etapa artística, localizado en una colección particular de Granada.

  2. Early Childhood Caries (ECC): an infectious transmissible oral disease

    NARCIS (Netherlands)

    H.R. Poureslami; W.E. van Amerongen

    2009-01-01

    Dental caries in babies and toddlers is called Early Childhood Caries (ECC). It is an infectious and transmissible die-to-bacterial disease. Detailed knowledge regarding the acquisition and transmission of infectious agents facilitates a more comprehensive approach toward prevention. Mutans streptoc

  3. Early Childhood Caries (ECC): an infectious transmissible oral disease

    NARCIS (Netherlands)

    Poureslami, H.R.; van Amerongen, W.E.

    2009-01-01

    Dental caries in babies and toddlers is called Early Childhood Caries (ECC). It is an infectious and transmissible die-to-bacterial disease. Detailed knowledge regarding the acquisition and transmission of infectious agents facilitates a more comprehensive approach toward prevention. Mutans

  4. Early Childhood Caries (ECC): an infectious transmissible oral disease

    NARCIS (Netherlands)

    Poureslami, H.R.; van Amerongen, W.E.

    2009-01-01

    Dental caries in babies and toddlers is called Early Childhood Caries (ECC). It is an infectious and transmissible die-to-bacterial disease. Detailed knowledge regarding the acquisition and transmission of infectious agents facilitates a more comprehensive approach toward prevention. Mutans streptoc

  5. Modeling of ECC materials using numerical formulations based on plasticity

    DEFF Research Database (Denmark)

    Dick-Nielsen, Lars; Stang, Henrik; Poulsen, Peter Noe

    2006-01-01

    This paper discusses the considerations for the establishment of a damage model for ECC. Three different length scales are used in the approach for deriving the damage model. On each length scale important phenomena are investigated by use of numerical and analytical calculations. On the micro sc...

  6. The microstructure of self-healed PVA ECC under wet and dry cycles

    Directory of Open Access Journals (Sweden)

    Jia Huan Yu

    2010-06-01

    Full Text Available Self-healing of ECC (Engineered Cementitious Composites subjected to cyclic wetting and drying regimes is investigated in this paper. ECC structures subjected to outdoor environmental conditions such as wind and rain runoff can be simulated by accelerated test method of wetting and drying cycles. Uniaxial tensile tests of ECC M45 and ECC 2.8FA specimen are conducted respectively. It is found that crack width of ECC 2.8FA is around 10 μm with increased amount of fly ash, while the crack width of ECC M45 is around 100 μm. New insights about the microstructure and chemical composition analysis of ECC specimens initially cracked to 2% strain and then self-healed under wet-dry cycles are presented.

  7. An overview of the BWR ECCS strainer blockage issues

    Energy Technology Data Exchange (ETDEWEB)

    Serkiz, A.W.; Marshall, M.L. Jr.; Elliott, R. [Nuclear Regulatory Commission, Washington, DC (United States)

    1996-03-01

    This Paper provides a brief overview of actions taken in the mid 1980s to resolve Unresolved Safety Issue (USI) A-43, {open_quotes}Containment Emergency Sump Performance,{close_quotes} and their relationship to the BWR strainer blockage issue; the importance of insights gained from the Barseback-2 (a Swedish BWR) incident in 1992 and from ECCS strainer testing and inspections at the Perry nuclear power plant in 1992 and 1993; an analysis of an US BWR/4 with a Mark I containment; an international community sharing of knowledge relevant to ECCS strainer blockage, additional experimental programs; and identification of actions needed to resolve the strainer blockage issue and the status of such efforts.

  8. HIGH SPEED POINT ARITHMETIC ARCHITECTURE FOR ECC ON FPGA

    Directory of Open Access Journals (Sweden)

    Rahila Bilal,

    2010-09-01

    Full Text Available Elliptic curve cryptography plays a crucial role in networking and communication security. ECC have evolved in the recent past as an important alternative to established systems like RSA. This paper describes the implementation of an elliptic curve coprocessor based on the FPGA , which can provide a significant speedup for these cryptosystems. The FPGA configuration file is synthesized from VHDL code applying different hardware synthesis products. The implementation of ECC lies in three levels: scalar multiplication, point addition/doubling and finite field modular arithmetic. In this paper, we present a novel fast architecture for the point addition/doubling level in the projective coordinate. The proposed Architecture is based on Binary Field. The Design performs multiplication using Polynomial Basis. Analysis shows that, with reasonable hardware overhead, our architecture can achieve a high speedup for the point addition operation and point Doubling operation.Furthermore, the architecture is parameterized for different data widths to evaluate the optimal resource utilization.

  9. Experimental Study on the Compressive Behavior of CFRP/ECCs

    Institute of Scientific and Technical Information of China (English)

    SUN Wen-bin

    2010-01-01

    In this study, nine square concrete columns, including six CFRP/ECCs and three plain concrete control specimen columns, were prepared. The CFRP tubes with fibers oriented in the hoop direction were manufactured with 10, 20, or 40 mm rounded corner radii at vertical edges. A 100 mm overlap in the direction of fibers was provided to ensure a proper bond. Uniaxial compression tests were conducted to investigate the compressive behaviors including the axial strength, stress-strain response, and ductility. It is evident that the CFRP tube confinement can improve the compressive behavior of concrete core, in terms of axial compressive strength or axial deformability. Based on the experimental results and some existing test database attained by other researchers, a design-oriented model is developed. The predictions of the model for CFRP/ECCs show good agreement with test results.

  10. Self-Healing of Microcracks in Engineered Cementitious Composites (ECC) Under a Natural Environment

    OpenAIRE

    Li, Victor C.; Emily N. Herbert

    2013-01-01

    This paper builds on previous self-healing engineered cementitious composites (ECC) research by allowing ECC to heal outdoors, in the natural environment, under random and sometimes extreme environmental conditions. Development of an ECC material that can heal itself in the natural environment could lower infrastructure maintenance costs and allow for more sustainable development in the future by increasing service life and decreasing the amount of resources and energy needed for repairs. Det...

  11. Feeding pattern a dual risk? otitis media (OM and early childhood caries (ECC

    Directory of Open Access Journals (Sweden)

    P. Sangeetha

    2014-04-01

    Full Text Available Purpose: To determine the prevalence of Otitis media (OM and Early childhood caries (ECC and their coexistence in children with a history of faulty feeding patterns. Method: Children aged 5 years and below were recruited at random from dental and medical hospitals. Parents of these children were posed with questions about the feeding methods, feeding patterns such as duration, frequency, position, burping, specific childhood illness etc. Children (120 were examined for ECC by a Paedodontist and OM by an Otolaryngologist and were segregated into three groups i.e. Control group, ECC group and OM group respectively. The ECC group was sub grouped into ECC only and ECC&OM group. The OM group was also similarly sub grouped into OM group and OM&ECC group. Collected data were tabulated and subjected for statistical analysis using Pearson Chi – square test. Results: Prevalence of ECC, OM, and their coexistence increased with age P < 0.001, whereas gender difference was not statistically significant. Overall Prevalence of their coexistence in children was 51.25%. Significant percentages (25% of children in the OM group were fed in supine position. Children fed on demand (47.5% experienced ECC. overall 85% (p=.017 of children had coexistence of ECC&OM fed on demand and during bed time. Significant numbers of children who were burped occasionally after feeding (35% or were not burped at all (12.5% were affected with both ECC and OM. Conclusion: Prevalence of their coexistence was higher in children with OM. Significant association existed between on demand feeding and ECC; supine feeding position and OM. Risk factors in common for both the disease were combined feeding position, on demand, bed time feeding and occasionally burping.

  12. eccCL: parallelized GPU implementation of Ensemble Classifier Chains.

    Science.gov (United States)

    Riemenschneider, Mona; Herbst, Alexander; Rasch, Ari; Gorlatch, Sergei; Heider, Dominik

    2017-08-17

    Multi-label classification has recently gained great attention in diverse fields of research, e.g., in biomedical application such as protein function prediction or drug resistance testing in HIV. In this context, the concept of Classifier Chains has been shown to improve prediction accuracy, especially when applied as Ensemble Classifier Chains. However, these techniques lack computational efficiency when applied on large amounts of data, e.g., derived from next-generation sequencing experiments. By adapting algorithms for the use of graphics processing units, computational efficiency can be greatly improved due to parallelization of computations. Here, we provide a parallelized and optimized graphics processing unit implementation (eccCL) of Classifier Chains and Ensemble Classifier Chains. Additionally to the OpenCL implementation, we provide an R-Package with an easy to use R-interface for parallelized graphics processing unit usage. eccCL is a handy implementation of Classifier Chains on GPUs, which is able to process up to over 25,000 instances per second, and thus can be used efficiently in high-throughput experiments. The software is available at http://www.heiderlab.de .

  13. Disease Management of Early Childhood Caries: ECC Collaborative Project.

    Science.gov (United States)

    Ng, Man Wai; Ramos-Gomez, Francisco; Lieberman, Martin; Lee, Jessica Y; Scoville, Richard; Hannon, Cindy; Maramaldi, Peter

    2014-01-01

    Until recently, the standard of care for early childhood caries (ECC) has been primarily surgical and restorative treatment with little emphasis on preventing and managing the disease itself. It is now recognized that surgical treatment alone does not address the underlying etiology of the disease. Despite costly surgeries and reparative treatment, the onset and progression of caries are likely to continue. A successful rebalance of risk and protective factors may prevent, slow down, or even arrest dental caries and its progression. An 18-month risk-based chronic disease management (DM) approach to address ECC in preschool children was implemented as a quality improvement (QI) collaborative by seven teams of oral health care providers across the United States. In the aggregate, fewer DM children experienced new cavitation, pain, and referrals to the operating room (OR) for restorative treatment compared to baseline historical controls. The teams found that QI methods facilitated adoption of the DM approach and resulted in improved care to patients and better outcomes overall. Despite these successes, the wide scale adoption and spread of the DM approach may be limited unless health policy and payment reforms are enacted to compensate providers for implementing DM protocols in their practice.

  14. Development of CANDU ECCS performance evaluation methodology and guides

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Kwang Hyun; Park, Kyung Soo; Chu, Won Ho [Korea Maritime Univ., Jinhae (Korea, Republic of)

    2003-03-15

    The objectives of the present work are to carry out technical evaluation and review of CANDU safety analysis methods in order to assist development of performance evaluation methods and review guides for CANDU ECCS. The applicability of PWR ECCS analysis models are examined and it suggests that unique data or models for CANDU are required for the following phenomena: break characteristics and flow, frictional pressure drop, post-CHF heat transfer correlations, core flow distribution during blowdown, containment pressure, and reflux rate. For safety analysis of CANDU, conservative analysis or best estimate analysis can be used. The main advantage of BE analysis is a more realistic prediction of margins to acceptance criteria. The expectation is that margins demonstrated with BE methods would be larger that when a conservative approach is applied. Some outstanding safety analysis issues can be resolved by demonstration that accident consequences are more benign than previously predicted. Success criteria for analysis and review of Large LOCA can be developed by top-down approach. The highest-level success criteria can be extracted from C-6 and from them, the lower level criteria can be developed step-by-step, in a logical fashion. The overall objectives for analysis and review are to verify radiological consequences and frequency are met.

  15. Disease Management of Early Childhood Caries: ECC Collaborative Project

    Directory of Open Access Journals (Sweden)

    Man Wai Ng

    2014-01-01

    Full Text Available Until recently, the standard of care for early childhood caries (ECC has been primarily surgical and restorative treatment with little emphasis on preventing and managing the disease itself. It is now recognized that surgical treatment alone does not address the underlying etiology of the disease. Despite costly surgeries and reparative treatment, the onset and progression of caries are likely to continue. A successful rebalance of risk and protective factors may prevent, slow down, or even arrest dental caries and its progression. An 18-month risk-based chronic disease management (DM approach to address ECC in preschool children was implemented as a quality improvement (QI collaborative by seven teams of oral health care providers across the United States. In the aggregate, fewer DM children experienced new cavitation, pain, and referrals to the operating room (OR for restorative treatment compared to baseline historical controls. The teams found that QI methods facilitated adoption of the DM approach and resulted in improved care to patients and better outcomes overall. Despite these successes, the wide scale adoption and spread of the DM approach may be limited unless health policy and payment reforms are enacted to compensate providers for implementing DM protocols in their practice.

  16. Mechanical Behavior of Rectangular Steel-Reinforced ECC/Concrete Composite Column under Eccentric Compression

    Institute of Scientific and Technical Information of China (English)

    潘金龙; 鲁冰; 顾大伟; 夏正昊; 夏天阳

    2015-01-01

    In order to improve the seismic performance, deformation ability and ultimate load-carrying capacity of columns with rectangular cross section, engineered cementitious composite (ECC) is introduced to partially substitute concrete in the edge zone of reinforced concrete columns and form reinforced ECC/concrete composite columns. Firstly, based on the assumption of plane remaining plane and the simplified constitutive models, the calculation method of the load-carrying capacity of reinforced ECC/concrete columns is proposed. The stress and strain distribu-tions and crack propagation of the composite columns in different states of eccentric compressive loading are ana-lyzed. Then, nonlinear finite element analysis is conducted to study the mechanical performance of reinforced ECC/concrete composite columns with rectangular cross section. It is found that the simulation results are in good agreement with the theoretical results, indicating that the proposed method for calculating the load-carrying capacity of concrete/ECC composite columns is valid. Finally, based on the proposed method, the effects of ECC thickness, com-pressive strength of concrete and longitudinal reinforcement ratio on the mechanical performance of reinforced ECC/concrete composite columns are analyzed. Calculation results indicate that increasing the thickness of ECC layer or longitudinal reinforcement ratio can effectively increase the ultimate load-carrying capacity of the composite column with both small and large eccentricity, but increasing the strength of concrete can only increase the ultimate load-carrying capacity of the composite column with small eccentricity.

  17. Combined group ECC protection and subgroup parity protection

    Energy Technology Data Exchange (ETDEWEB)

    Gara, Alan; Cheng, Dong; Heidelberger, Philip; Ohmacht, Martin

    2016-02-02

    A method and system are disclosed for providing combined error code protection and subgroup parity protection for a given group of n bits. The method comprises the steps of identifying a number, m, of redundant bits for said error protection; and constructing a matrix P, wherein multiplying said given group of n bits with P produces m redundant error correction code (ECC) protection bits, and two columns of P provide parity protection for subgroups of said given group of n bits. In the preferred embodiment of the invention, the matrix P is constructed by generating permutations of m bit wide vectors with three or more, but an odd number of, elements with value one and the other elements with value zero; and assigning said vectors to rows of the matrix P.

  18. Combined group ECC protection and subgroup parity protection

    Science.gov (United States)

    Gara, Alan G.; Chen, Dong; Heidelberger, Philip; Ohmacht, Martin

    2013-06-18

    A method and system are disclosed for providing combined error code protection and subgroup parity protection for a given group of n bits. The method comprises the steps of identifying a number, m, of redundant bits for said error protection; and constructing a matrix P, wherein multiplying said given group of n bits with P produces m redundant error correction code (ECC) protection bits, and two columns of P provide parity protection for subgroups of said given group of n bits. In the preferred embodiment of the invention, the matrix P is constructed by generating permutations of m bit wide vectors with three or more, but an odd number of, elements with value one and the other elements with value zero; and assigning said vectors to rows of the matrix P.

  19. [Combination surgery (ECCE+IOL+TE) and intraocular pressure levels].

    Science.gov (United States)

    Hornová, J

    1997-08-01

    The authors investigated the effect of a combined operation, ECCE + TE + IOL, on reduction of intraocular pressure (IOP), changes in antiglaucomatous treatment and on vision six months after operation. In 1994 36 eyes were operated, 16 eyes with primary open angle glaucoma (POAG), 8 eyes with angular glaucoma (PACG) and 12 eyes with marked exfoliative syndrome (CG). Six months after operation the IOP declined from 26.4 mm Hg to 13.3 mm Hg (P 0.05), antiglaucomatous treatment was reduced from 2.55 to 1.11 (P 0.05), vision improved by 0.39, i.e. by 2-3 lines of optotypes (P 0.05). 89% of the operated patients have a vision better than 0.5. Comparison of values before and after operation revealed a more marked drop of IOP in CG (P 0.05) than in POAG.

  20. Refractive results after phacoemulsification and ECCE. A comparative study.

    Science.gov (United States)

    Dam-Johansen, M; Olsen, T

    1993-06-01

    The refractive results were evaluated in 79 patients undergoing cataract extraction by phacoemulsification using a 6-7 mm tunnel incision, and compared with a group of 77 patients undergoing planned extracapsular cataract extraction (ECCE) by the same surgeon. A mean increase in the keratometric cylinder of 0.05D and 0.52D was found in the phacoemulsification and the extracapsular cataract extraction group, respectively. This was significantly different from zero for the extracapsular cataract extraction group (p 0.05). By vector analysis, the mean surgically induced astigmatism was 0.91D and 1.36D in the phacoemulsification and the extracapsular cataract extraction group, respectively (p < 0.01). The IOL power prediction error (spectacle plane) was found to be 0.17D (+/- 0.69 SD) in the phacoemulsification group and 0.02 D (+/- 0.79 SD) in the extracapsular cataract extraction group, respectively. We conclude that phacoemulsification improves the surgical control of the refractive outcome of cataract surgery.

  1. Manual ECCE, the present state of the art.

    Science.gov (United States)

    Blumenthal, M

    1994-11-01

    Manual ECCE has proved to be safe surgery compatible with small incision, no stitches, possible topical anesthesia, very cost effective and quick rehabilitation. The technique has a learning curve and needs experience. "Mini-nuc" stands for mini nucleus. This surgery can be achieved only if performed under positive intraocular pressure (IOP). A BSS bottle is connected to the eye by an anterior chamber maintainer (ACM). The height of the BSS bottle controls the IOP during the surgery. Controlled IOP is a principle suggested for all kinds of cataract surgery. It creates continuous flow which washes out of the eye cortex debris, blood, pigment, etc. The BSS contains antibiotics and adrenalin, it creates low turbulence due to the small amount of BSS used per case, 30-50 cc. A round capsulorhexis is essential. A special way of hydrodissection creates a very small hard core nucleus delivered to the anterior chamber and is extracted out through a sclero-corneal tunnel using a glide introduced under the nucleus to guide the nucleus out. Positive IOP during all stages of surgery creates the best operative conditions for controlled surgery throughout all manipulations. This technique is a very cost effective system and at the same time provides a high quality procedure.

  2. Application of Interfacial Propagation and Kinking Crack Concept to ECC/Concrete Overlay Repair System

    Directory of Open Access Journals (Sweden)

    Yaw ChiaHwan

    2014-01-01

    Full Text Available Research on the application of ultraductile engineered cementitious composite (ECC as overlay in the repair of deteriorated concrete structures is performed in this paper. Also, interfacial crack kinking and trapping mechanism experimentally observed in ECC/concrete overlay repair system are described by comparison of toughness and energy release rate. The mechanism involves cycles of extension, kinking, and arrest of interfacial crack into the overlay. Experimental testing of overlay repair system reveals significant improvements in load carrying capacity and ductility over conventional concrete overlay. The commonly observed overlay system failure mode of delamination or spalling is eliminated when ECC is applied. These failure modes are suppressed when ECC is used as an ideal and durable candidate overlay repair material.

  3. Preestrita pihtimus : Friedrich Nietzsche ja tema substantsiaalne mina (Ecce homo) / Jaan Undusk

    Index Scriptorium Estoniae

    Undusk, Jaan, 1958-

    1998-01-01

    Varem ilmunud raamatu järelsõnana: Nietzsche, Friedrich. Ecce homo : kuidas saadakse selleks, mis ollakse / tlk. Jaan Undusk. Tallinn : Vagabund, 1996. Sisu: Poeetiline, filosoofiline, dionüüsiline kaanon ; Künism contra hulluskahtlus ; Antikristlik pihtimus ; Egoretoorika

  4. Preestrita pihtimus : Friedrich Nietzsche ja tema substantsiaalne mina (Ecce homo) / Jaan Undusk

    Index Scriptorium Estoniae

    Undusk, Jaan, 1958-

    1998-01-01

    Varem ilmunud raamatu järelsõnana: Nietzsche, Friedrich. Ecce homo : kuidas saadakse selleks, mis ollakse / tlk. Jaan Undusk. Tallinn : Vagabund, 1996. Sisu: Poeetiline, filosoofiline, dionüüsiline kaanon ; Künism contra hulluskahtlus ; Antikristlik pihtimus ; Egoretoorika

  5. Experimental Study of the APR+ Direct ECC Bypass in the Air-water Test Facility

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Kihwan; Choi, Hae-Seob; Park, Kil-won; Kwon, Tae-Soon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    The APR+ is an improved Korean Nuclear Power Reactor, which has been developed as a two loop evolutionary PWR (Pressure Water Reactor) with a number of advanced design features to enhance safety based on the APR-1400 technology. The emergency core cooling system (ECC) of the APR+ is different with that of the APR-1400, though the APR+ adopted a direct vessel injection (DVI) system which is the same design features of the APR-14000. The main difference of the DVI+ is the emergency core barrel duct (ECBD) which is designed to increase the amount of the injection water to the core region. The performance of the DVI system has been an important issues for past decades, and many researchers have studied the related thermal-hydraulic technical issues such as the ECC bypass fraction, the steam condensation effect, temperature distribution, sub-cooling margin, and etc. However, the previous research cannot be directly applicable to the APR+ owing to the unique features of the DVI+. The current study will elaborate on the experimental evaluation of the direct ECC bypass performance. The 1/5 ECC bypass test facility which is designed with a linearly reduced 1/5 scale referring to the APR+ was used to investigate the effect of the DVI+ injection nozzle location and the broken cold leg velocity on the direct ECC bypass fraction. However, air is used as a working fluid to simulate the steam flow induced from the broken cold leg, and thus, the direct contact condensation effect is not considered in this study. Experimental study for the direct ECC bypass phenomena has been carryout out with various the injection mode and air velocity conditions. The tests were performed in the 1/5 scale ECC bypass test facility, and the test condition was defined using a scaling law referring to the APR+ reactor. Test results showed that the direct ECC bypass fraction was greatly enhanced compared with the reference test (w/o ECBD)

  6. New External Calibration Curves (ECCs) for the Estimation of Molecular Weights in Various Common NMR Solvents.

    Science.gov (United States)

    Bachmann, Sebastian; Neufeld, Roman; Dzemski, Martin; Stalke, Dietmar

    2016-06-13

    New external calibration curves (ECCs) for the estimation of aggregation states of small molecules in solution by DOSY NMR spectroscopy for a range of different common NMR solvents ([D6 ]DMSO, C6 D12 , C6 D6 , CDCl3 , and CD2 Cl2 ) are introduced and applied. ECCs are of avail to estimate molecular weights (MWs) from diffusion coefficients of previously unknown aggregates. This enables a straightforward and elaborate examination of (de)aggregation phenomena in solution.

  7. Self-Healing of Microcracks in Engineered Cementitious Composites (ECC Under a Natural Environment

    Directory of Open Access Journals (Sweden)

    Victor C. Li

    2013-07-01

    Full Text Available This paper builds on previous self-healing engineered cementitious composites (ECC research by allowing ECC to heal outdoors, in the natural environment, under random and sometimes extreme environmental conditions. Development of an ECC material that can heal itself in the natural environment could lower infrastructure maintenance costs and allow for more sustainable development in the future by increasing service life and decreasing the amount of resources and energy needed for repairs. Determining to what extent current ECC materials self-heal in the natural environment is the first step in the development of an ECC that can completely heal itself when exposed to everyday environmental conditions. This study monitored outdoor ECC specimens for one year using resonant frequency (RF and mechanical reloading to determine the rate and extent of self-healing in the natural environment. It was found that the level of RF, stiffness, and first cracking strength recovery increased as the duration of natural environment exposure increased. For specimens that underwent multiple damage cycles, it was found that the level of recovery was highly dependent on the average temperature and amount of precipitation between each damage event. However, RF, stiffness, and first cracking strength recovery data for specimens that underwent multiple loading cycles suggest that self-healing functionality can be maintained under multiple damage events.

  8. Self-Healing of Microcracks in Engineered Cementitious Composites (ECC) Under a Natural Environment.

    Science.gov (United States)

    Herbert, Emily N; Li, Victor C

    2013-07-15

    This paper builds on previous self-healing engineered cementitious composites (ECC) research by allowing ECC to heal outdoors, in the natural environment, under random and sometimes extreme environmental conditions. Development of an ECC material that can heal itself in the natural environment could lower infrastructure maintenance costs and allow for more sustainable development in the future by increasing service life and decreasing the amount of resources and energy needed for repairs. Determining to what extent current ECC materials self-heal in the natural environment is the first step in the development of an ECC that can completely heal itself when exposed to everyday environmental conditions. This study monitored outdoor ECC specimens for one year using resonant frequency (RF) and mechanical reloading to determine the rate and extent of self-healing in the natural environment. It was found that the level of RF, stiffness, and first cracking strength recovery increased as the duration of natural environment exposure increased. For specimens that underwent multiple damage cycles, it was found that the level of recovery was highly dependent on the average temperature and amount of precipitation between each damage event. However, RF, stiffness, and first cracking strength recovery data for specimens that underwent multiple loading cycles suggest that self-healing functionality can be maintained under multiple damage events.

  9. 基于FPGA的椭圆曲线密码(ECC)算法硬件设计%Hardware Design of Elliptic Curve Cryptography(ECC) Based on FPGA

    Institute of Scientific and Technical Information of China (English)

    赵曼; 徐和根

    2013-01-01

    Elliptic curve cryptosystem ( ECC) is a public key encryption system with the most secure unit key security at present, the application of FPGA and hardware design to implement the ECC cryptography have become a concern in the field of information security. The further study of the elliptic curve encryption and decryption is based on the theory, using the verilog hardware description language and schematic design method to achieve the ECC encryption algorithm, with high-speed and low-power characteristics.%椭圆曲线密码体制(elliptic curve cryptosystem,ECC)是目前已知的单位密钥安全性最高的一种公钥加密体制,使用FPGA等硬件设计方法来实现ECC密码系统已成为信息安全领域引人关注的研究.该文在深入研究椭圆曲线加解密理论基础上,使用Verilog硬件描述语言和原理图输入法共同实现了ECC加密算法,具有高速、低功耗的特点.

  10. Energy-dissipating and self-repairing SMA-ECC composite material system

    Science.gov (United States)

    Li, Xiaopeng; Li, Mo; Song, Gangbing

    2015-02-01

    Structural component ductility and energy dissipation capacity are crucial factors for achieving reinforced concrete structures more resistant to dynamic loading such as earthquakes. Furthermore, limiting post-event residual damage and deformation allows for immediate re-operation or minimal repairs. These desirable characteristics for structural ‘resilience’, however, present significant challenges due to the brittle nature of concrete, its deformation incompatibility with ductile steel, and the plastic yielding of steel reinforcement. Here, we developed a new composite material system that integrates the unique ductile feature of engineered cementitious composites (ECC) with superelastic shape memory alloy (SMA). In contrast to steel reinforced concrete (RC) and SMA reinforced concrete (SMA-RC), the SMA-ECC beams studied in this research exhibited extraordinary energy dissipation capacity, minimal residual deformation, and full self-recovery of damage under cyclic flexural loading. We found that the tensile strain capacity of ECC, tailored up to 5.5% in this study, allows it to work compatibly with superelastic SMA. Furthermore, the distributed microcracking damage mechanism in ECC is critical for sufficient and reliable recovery of damage upon unloading. This research demonstrates the potential of SMA-ECC for improving resilience of concrete structures under extreme hazard events.

  11. Holistic care patient with Early Childhood Caries (ECC: A case report

    Directory of Open Access Journals (Sweden)

    Intan Maulani

    2016-06-01

    Full Text Available Early Childhood Caries (ECC is a specific form of severe dental caries that affects infants and young children. ECC progresses rapidly in those who are at high risk, and often goes untreated. Children experiencing caries as infants or toddlers have a much greater probability of subsequent caries in both primary and permanent dentitions. This case showed management holistic care for children with ECC.A five year old boy patient accompanied with her parents were reported to the Pedodontic Clinic Padjadjaran University Dental Hospital with a chief complaint of decayed upper anterior teeth and pain in the molar teeth. Clinical examinations found dental caries almost all teeth in the maxilla and mandible. Based on panoramic radiograph, treatments that can be done are strip crown glass ionomer restorations, pulp treatments, extractions and fixed space maintainer. Patients diagnosed with severe ECC, patient and parents described on this type of caries. During treatment the patient was given oral hygiene instruction and recommend daily use of tooth mouse. After all treatment were completed, fluoride topical, and fissure sealants, recall check up after three months was scheduled. Holistic care needed in handling children with ECC.

  12. Comparison of outcomes following combined ECCE-trabeculectomy versus phacoemulsification-trabeculectomy.

    Science.gov (United States)

    Tous, Horacio M; Nevárez, Juan

    2006-12-01

    To analyze and compare the main outcomes between trabeculectomies combined with extracapsular cataract extraction (ECCE) versus those with phacoemulsification (Phaco). The authors retrospectively reviewed one surgeon's 357 consecutive cases (475 eyes) of combined cataract extraction, intraocular lens implantation and Mitomycin enhanced trabeculectomy. Patients were divided into two groups, those who underwent extracapsular cataract extraction (80 eyes) and those having phacoemulsification (395 eyes). Analysis of postoperative visual acuity, intraocular pressure (IOP), number of glaucoma medications, postoperative adverse events and additional procedures required, was done. Minimum follow-up was 12 months with an average of 53 months. There was no significant difference (p = 1.000) between the groups in terms of visual acuity improvement rate, 66% (ECCE) versus 59% (Phaco). Postoperatively IOP with both techniques fell significantly (p ECCE vs. 14.1 mmHg Phaco, p = 1.0000). Postoperative pressure spikes occurred in 6% versus 10% (p = 0.3995) of the eyes. No significant difference (55% ECCE versus 63% Phaco, p = 0.1674) between the two groups in terms of glaucoma medication reduction was found. The total number of postoperative complications (89% versus 68.5%) were significantly higher (p = 0.0001) in the ECCE-group, as well as the total number of eyes which required further interventions (86% versus 64%, p = 0.0001). Both combined surgery techniques are effective and yielded similar long-term results. However phacoemulsification can decrease the post operative complications associated with this surgery.

  13. Lightweight ECC based RFID authentication integrated with an ID verifier transfer protocol.

    Science.gov (United States)

    He, Debiao; Kumar, Neeraj; Chilamkurti, Naveen; Lee, Jong-Hyouk

    2014-10-01

    The radio frequency identification (RFID) technology has been widely adopted and being deployed as a dominant identification technology in a health care domain such as medical information authentication, patient tracking, blood transfusion medicine, etc. With more and more stringent security and privacy requirements to RFID based authentication schemes, elliptic curve cryptography (ECC) based RFID authentication schemes have been proposed to meet the requirements. However, many recently published ECC based RFID authentication schemes have serious security weaknesses. In this paper, we propose a new ECC based RFID authentication integrated with an ID verifier transfer protocol that overcomes the weaknesses of the existing schemes. A comprehensive security analysis has been conducted to show strong security properties that are provided from the proposed authentication scheme. Moreover, the performance of the proposed authentication scheme is analyzed in terms of computational cost, communicational cost, and storage requirement.

  14. Intraocular pressure following ECCE and IOL implantation in patients with glaucoma.

    Science.gov (United States)

    Kooner, K S; Dulaney, D D; Zimmerman, T J

    1988-08-01

    Patients with glaucoma may suffer optic nerve head damage due to elevated intraocular pressure (IOP) after any intraocular procedure. We retrospectively reviewed the IOP data in 82 consecutive patients (103 eyes) with glaucoma after extracapsular cataract extraction (ECCE) and posterior chamber intraocular lens (PC-IOL) implantation. Nine eyes had previous trabeculectomy and three eyes required combined trabeculectomy with ECCE and PC-IOL. The average follow-up period is 1.5 years (range 0.5 to 6 years). The postoperative IOP rise of 8 mm Hg over baseline or above 23 mm Hg was observed in 45 eyes (49.5%). Two eyes needed argon laser trabeculoplasty and one required trabeculectomy to control postoperative IOP elevation. Most of the patients required the same or lesser number of medications for IOP control after surgery. Results suggest that ECCE with PC-IOL may be a relatively safe procedure in cataract patients with preexisting glaucoma.

  15. Clinical outcomes and costs of cataract surgery performed by planned ECCE and phacoemulsification.

    Science.gov (United States)

    Castells, X; Comas, M; Castilla, M; Cots, F; Alarcón, S

    1998-01-01

    To compare clinical outcomes and costs of cataract surgery between patients operated with standard extracapsular extraction (ECCE) and those undergoing phacoemulsification. Patients from the Ophthalmology Department of a teaching hospital in Barcelona (Spain) scheduled for cataract surgery, not combined with any other ophthalmic procedure. A retrospective analysis has been performed on a database of 1046 patients undergoing ECCE and phacoemulsification. The outcome measures used were: surgical complications, visual acuity and costs of surgery and of follow-up. Overall rate of all complications and postoperative visual acuity were compared between the two groups, adjusting for age, preoperative visual acuity, medical and ocular comorbidity. 31.9% of the patients (334) underwent phacoemulsification, and 68.1% (712) underwent ECCE. Patients undergoing phacoemulsification presented a frequency of intra- and postoperative complications lower than those undergoing ECCE (odds ratio 0.57, 95%CI 0.37-0.87 and 0.66, 95%CI 0.46-0.96, respectively), specifically for intraoperative iris trauma (3.1% vs 0.3%, p = 0.004), residual posterior capsular opacity (2% vs 0.3%, p = 0.035) and postoperative corneal edema (7.4% vs 3.6%, p = 0.016). Costs of intervention and follow-up were lower for phacoemulsification compared with ECCE (23.9% and 14%, respectively). But global costs were slightly higher for phacoemulsification (4.87%), due to supply costs, which were more than twice those of ECCE. Phacoemulsification, when performed by an experienced surgeon, has better clinical outcomes than planned extracapsular extraction, and costs may be lower since supply costs are expected to decrease as the phacoemulsification technique becomes more widespread.

  16. BREASTFEEDING AND EARLY CHILDHOOD CARIES (ECC SEVERITY OF CHILDREN UNDER THREE YEARS OLD IN DKI JAKARTA

    Directory of Open Access Journals (Sweden)

    Risqa Rina Darwita

    2008-12-01

    Full Text Available The prevalence and severity of caries in children under three years old are constantly increasing. One of the cause is the increase consumption of cariogenic carbohydrate. Breast milk have buffer capacity that eventually able to prevent caries. The aims of this research are to discover the correlation between breastfeeding with the severity of Early Childhood Caries (ECC in children under three years old, to provide information on prevalence and severity of caries in children under three years, and to explain factors influencing the incidence of ECC. This research designed cross sectionally and conducted upon 565 children aged 12-38 months, selected using multistage cluster random sampling. The ECC prevalence of children under three years in DKI Jakarta is 52.7%, with average score of def-t 2.85. Bivariate analysis showed that, variables which correlate with the level of ECC are; the way to deliver (p=0,012, frequency (p=0,002, duration (p=0,002, salivary buffer capacity (p=0.013, habitual consumption of sugary diet (p=0.005, child’s dental hygiene behavior (p=0.002, and mother’s education (p=0.001. Multivariate analysis showed that ECC can be explained by these variables: age, mother’s education, the way to deliver and frequency of breast milk complements/replacement of consumtions, child’s brushing habit, plaque pH, and salivary buffer capacity. Resulting determination coefficient 32.1%. There is no significant correlation between breastfeeding and the level of Early Childhood Caries (ECC. The role of protective qualities of breastfeeding are not shown because of bias in obtaining data influence the incidence of caries.

  17. MICROORGANISMS FOUND IN SECONDARY CATARACT MATERIAL OF ECCE PATIENTS, A STUDY WITH SEM AND TEM

    NARCIS (Netherlands)

    KALICHARAN, D; JONGEBLOED, WL; LOS, LI; WORST, JGF

    1993-01-01

    Globular secondary cataract material, removed from 24 patients with ECCE after ophthalmic cleaning of the anterior capsule, were investigated with SEM and TEM. Besides spherical, somewhat oval shaped bodies of various shape and size comparable with those found in cataractous lenses, (an)aerobic

  18. Zirconia crowns--an esthetic and resistant restorative alternative for ECC affected primary teeth.

    Science.gov (United States)

    Planells del Pozo, P; Fuks, A B

    2014-01-01

    The present report discusses briefly the problem of ECC in very young children and the recommended approaches for prevention and treatment. The esthetic restoration of the maxillary incisors with Zirconia Nu Smile crowns is described. It is also stressed that the luxation injury two months after placement did not damage the appearance nor the stability of the crowns.

  19. Complete genome sequences of Escherichia coli strains 1303 and ECC-1470 isolated from bovine mastitis

    NARCIS (Netherlands)

    Leimbach, Andreas; Poehlein, Anja; Witten, Anika; Scheutz, Flemming; Schukken, Ynte; Daniel, Rolf; Dobrindt, Ulrich

    2016-01-01

    Escherichia coli is the leading causative agent of acute bovine mastitis. Here, we report the complete genome sequence of E. coli O70:H32 strain 1303, isolated from an acute case of bovine mastitis, and E. coli Ont:Hnt strain ECC-1470, isolated from a persistent infection.

  20. Candida albicans Carriage in Children with Severe Early Childhood Caries (S-ECC) and Maternal Relatedness

    Science.gov (United States)

    Xiao, Jin; Moon, Yonghwi; Li, Lihua; Rustchenko, Elena; Wakabayashi, Hironao; Zhao, Xiaoyi; Feng, Changyong; Gill, Steven R.; McLaren, Sean; Malmstrom, Hans; Ren, Yanfang; Quivey, Robert

    2016-01-01

    Introduction Candida albicans has been detected together with Streptococcus mutans in high numbers in plaque-biofilm from children with early childhood caries (ECC). The goal of this study was to examine the C. albicans carriage in children with severe early childhood caries (S-ECC) and the maternal relatedness. Methods Subjects in this pilot cross-sectional study were recruited based on a convenient sample. DMFT(S)/dmft(s) caries and plaque scores were assessed during a comprehensive oral exam. Social-demographic and related background information was collected through a questionnaire. Saliva and plaque sample from all children and mother subjects were collected. C. albicans were isolated by BBL™ CHROMagar™ and also identified using germ tube test. S. mutans was isolated using Mitis Salivarius with Bacitracin selective medium and identified by colony morphology. Genetic relatedness was examined using restriction endonuclease analysis of the C. albicans genome using BssHII (REAG-B). Multilocus sequence typing was used to examine the clustering information of isolated C. albicans. Spot assay was performed to examine the C. albicans Caspofungin susceptibility between S-ECC children and their mothers. All statistical analyses (power analysis for sample size, Spearman’s correlation coefficient and multiple regression analyses) were implemented with SAS 9.4 Results A total of 18 S-ECC child-mother pairs and 17 caries free child-mother pairs were enrolled in the study. Results indicated high C. albicans carriage rate in the oral cavity (saliva and plaque) of both S-ECC children and their mothers (>80%). Spearman’s correlation coefficient also indicated a significant correlation between salivary and plaque C. albicans and S. mutans carriage (p60% of them demonstrated identical C. albicans REAG-B pattern. C. albicans isolated from >65% of child-mother pairs demonstrated similar susceptibility to caspofungin in spot assay, while no caspofungin resistant strains were

  1. Preparation and evaluation of {sup 68}Ga-ECC as a PET renal imaging agent

    Energy Technology Data Exchange (ETDEWEB)

    Mizaei, Alireza; Jaililan, Amir Reza; Mazidi, Mohammad; Aghanejad, Ayuob; Yousefnia, Hassan; Shabani, Gholamli; Ardaneh, Khosro [Radiation Application Research School, Nuclear Science and Technology Research Institute, Tehran (Iran, Islamic Republic of); Geramifar, Patham; Beiki, Davood [Research Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran (Iran, Islamic Republic of)

    2015-09-15

    Development of a gallium-68-labeled renal tracer can be a good substitute for Tc-99m, a known SPECT tracer. In this study, effort was made to develop {sup 68}Ga-ethylenecysteamine cysteine ({sup 68}Ga-ECC). Ga-ECC was prepared using generator-based {sup 68}GaCl3 and ethylenecysteamine cysteine (ECC) at optimized conditions. Stability of the complex was checked in human serum followed by partition coefficient determination of the tracer. The biodistribution of the tracer in rats was studied using tissue counting and PET/CT imaging up to 120 min. Ga-ECC was prepared at optimized conditions in 15 min at 90 °C (radiochemical purity ≈97 ± 0.88 % ITLC, >99 % HPLC, specific activity: 210 ± 5 GBq/mM). {sup 68}Ga-ECC was a water-soluble complex based on partition coefficient data (log P; −1.378) and was stable in the presence of human serum for 2 h at 37 °C. The biodistribution of the tracer demonstrated high kidney excretion of the tracer in 10–20 min. The SUV{sub max} ratios of the liver to left kidney were 0.38 and 0.39 for 30 and 90 min, respectively, indicating high kidney uptake. Initial biodistribution results showed significant kidney and urinary excretion of the tracer comparable to that of the homologous {sup 99m}Tc compound. The complex could be a possible PET kidney imaging agent with a fast imaging time.

  2. Scaling of the direct ECC bypass during LBLOCA reflood phase with direct vessel injection system

    Energy Technology Data Exchange (ETDEWEB)

    Yun, B.J.; Kwon, T.S.; Song, C.H.; Jeong, J.J. [Korea Atomic Energy Research Inst., Taejon (Korea, Republic of); Cho, H.K.; Park, G.C. [Seoul National Univ., Dept. of Nuclear Engineering (Korea, Republic of)

    2001-07-01

    As one of the advanced design features of the Korea next generation reactor, direct vessel injection (DVI) system is being considered instead of conventional cold leg injection (CLI) system. It is known that the DVI system greatly enhances the reliability of the emergency core cooling (ECC) system. However, there is still a dispute on its performance in terms of water delivery to the reactor core during the reflood period of a large-break loss-of-coolant accident (LOCA). Thus, experimental validation is under progress. In this paper, a new scaling method, using time and velocity reduced linear scaling law, is suggested for the design of a scaled-down experimental facility to investigate the direct ECC bypass phenomena in PWR downcomer. (authors)

  3. Modifying the ECC-based grouping-proof RFID system to increase inpatient medication safety.

    Science.gov (United States)

    Ko, Wen-Tsai; Chiou, Shin-Yan; Lu, Erl-Huei; Chang, Henry Ker-Chang

    2014-09-01

    RFID technology is increasingly used in applications that require tracking, identification, and authentication. It attaches RFID-readable tags to objects for identification and execution of specific RFID-enabled applications. Recently, research has focused on the use of grouping-proofs for preserving privacy in RFID applications, wherein a proof of two or more tags must be simultaneously scanned. In 2010, a privacy-preserving grouping proof protocol for RFID based on ECC in public-key cryptosystem was proposed but was shown to be vulnerable to tracking attacks. A proposed enhancement protocol was also shown to have defects which prevented proper execution. In 2012, Lin et al. proposed a more efficient RFID ECC-based grouping proof protocol to promote inpatient medication safety. However, we found this protocol is also vulnerable to tracking and impersonation attacks. We then propose a secure privacy-preserving RFID grouping proof protocol for inpatient medication safety and demonstrate its resistance to such attacks.

  4. Nd:YAG laser removal of pupillary membranes developed after ECCE with PC-IOL implantation.

    Science.gov (United States)

    Kozobolis, V P; Pallikaris, I G; Tsambarlakis, I G; Vlachonikolis, I G

    1997-12-01

    To define the frequency of development of pupillary membranes after ECCE with PC-IOL implantation, and to remove the pupillary membranes using the Nd:YAG laser. From 400 patients who had undergone ECCE and were free from local or systemic illness affecting the blood-ocular barrier, 20 eyes developed pupillary membranes Nd:YAG laser was used to remove these pupillary membranes. The frequency of pupillary membranes was found to be 5% (9.8% in pex eyes and 3.3% to the non-pex eyes). Visual acuity improved in 17 eyes by 2 to 5 Snellen lines. No serious complications were observed, endothelium inclusive. Pseudoexfoliation might play a significant role in the development of postoperative pupillary membranes which could be successfully treated with the use of Nd:YAG laser. The safety of the procedure has to be evaluated in relation to the corneal endothelium damage in long-term.

  5. [ECCE with self-sealing cataract incision. Technique and clinical results].

    Science.gov (United States)

    Pham, D T; Wollensak, J; Drosch, S

    1995-06-01

    We present of modified technique for sutureless ECCE with a trapezoidal tunnel incision of 11 mm. The operation can be performed in a closed system because of the self-sealing wound construction. Compared to the sutured corneoscleral ECCE the new procedure has important advantages: the procedure is safe even during the critical phase following nucleus extraction. The procedure is therefore safer, faster, more economical and suture-induced astigmatism is avoided. Clinical experience after 2 years showed that postoperative complications were reduced significantly. Iris prolapse, wound dehiscens and hyphema occurred at a rate of 2%. The astigmatism (Jaffe analysis) was at a rate of 2 D, stable within 4 weeks after surgery, and did not change up to 2 years postoperatively. The astigmatism induced was then reduced about 0.5 D by a radical suture.

  6. Prosthetic Oral Rehabilitation of a Child With S-ECC: A Case Report with Histopathologic Analysis.

    Science.gov (United States)

    Tannure, P N; Moraes, G G; Borba, McU; Abrahão, A; Andrade, Mtrc; Fidalgo, Tks

    2015-01-01

    The aim of this case report is to describe the treatment planning of a young child with severe early childhood caries (S-ECC) as well as the prosthetic rehabilitation technique. A 3-year-old female child was referred to the pediatric dentistry clinic with the chief complaint of tooth pain, difficulty in eating and recurrent hospitalizations caused by dental infections. The mother reported intermittent episodes of fever and recurrent swelling of child's face. The girl presented angular cheilitis and was referred to a dietitian. The treatment plain consisted on a behavior changes in oral hygiene habits, exodontias of all primary teeth and oral rehabilitation with a prosthesis. The extracted teeth with periapical lesions were submitted to histopathologic analysis (hematoxilin and eosin staining) and revealed an inflammatory infiltrate. The aesthetic requirement of children with S-ECC has been a challenge to pediatric dentists. In the present case, the oral rehabilitation provided for the children better aesthetic, nutrition, phonation, and functional conditions.

  7. Comparison of data on Early Childhood Caries (ECC) with previous data for Baby Bottle Tooth Decay (BBTD) in an Italian kindergarten population.

    Science.gov (United States)

    Ferro, R; Besostri, A; Meneghetti, B; Beghetto, M

    2004-06-01

    This was to assess the prevalence of Early Childhood Caries (ECC) among preschool children attending nursery schools and to compare the results with those of a previous survey where the investigators used the term and diagnosis for Baby Bottle Tooth Decay (BBTD) syndrome. A cross-sectional survey of 1006 children aged 1-6 years was carried out. WHO recommendations for oral health surveys were used for caries diagnosis (non cavitated lesions were excluded). In addition, a comparison was made for prevalence of ECC between immigrant and native born children. Data were compared for ECC in the present survey with BBTD data in a previous study (1994) in the same area with a sample of 401 children aged 4 years. All examinations were by one examiner (Cohen's Kappa=0.96). Of the 1006 children originally selected 52 children aged more than 71 months were excluded according to published ECC definition and diagnostic criteria. The overall sample was 29 children aged <36 months; 271 aged 3 years; 364 aged 4 years and 290 aged 5 years. ECC was diagnosed in 19.7% of the overall sample. The prevalence of ECC (and S-ECC) were respectively by age: <36 months S-ECC=17.2%; at 3 years: 13.28% (6.64%); at 4 years: 18.95% (9.34%); at 5 years: 26.9% (12.75%). In the native born children (916) the ECC was 18.34%, while in immigrants (38) it was 52.63% (p<0.001). In 1994 the prevalence of BBTD syndrome was 11.9% and in the present study 6.5%. The ECC prevalence, as, ECC and severe (S-ECC),increased with age. In immigrant children ECC was 3 times (S-ECC 6 times) more frequent than in native born. Using the BBTD diagnosis the prevalence had dropped from 11.9% in 1994 to 6.5% in the present survey.

  8. A Secure-Enhanced Data Aggregation Based on ECC in Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Qiang Zhou

    2014-04-01

    Full Text Available Data aggregation is an important technique for reducing the energy consumption of sensor nodes in wireless sensor networks (WSNs. However, compromised aggregators may forge false values as the aggregated results of their child nodes in order to conduct stealthy attacks or steal other nodes’ privacy. This paper proposes a Secure-Enhanced Data Aggregation based on Elliptic Curve Cryptography (SEDA-ECC. The design of SEDA-ECC is based on the principles of privacy homomorphic encryption (PH and divide-and-conquer. An aggregation tree disjoint method is first adopted to divide the tree into three subtrees of similar sizes, and a PH-based aggregation is performed in each subtree to generate an aggregated subtree result. Then the forged result can be identified by the base station (BS by comparing the aggregated count value. Finally, the aggregated result can be calculated by the BS according to the remaining results that have not been forged. Extensive analysis and simulations show that SEDA-ECC can achieve the highest security level on the aggregated result with appropriate energy consumption compared with other asymmetric schemes.

  9. Convento del Santo Ecce-Homo síntesis histórica y esbozo analítico

    Directory of Open Access Journals (Sweden)

    Alberto Corradine

    2012-08-01

    Full Text Available Convento del Santo ECCE-HOMO, Síntesis histórica y esbozo-analítico/ Alberto Corradine. No. 6-7, 1971-1972; p. 57-68. El autor describe y analiza el estilo arquitectónico del ECCE-HOMO señalando especialmente la influencia del estilo mudejar venido de España en el siglo XVII. 

  10. Convento del santo ecce-homo síntesis histórica y esbozo analítico

    OpenAIRE

    Alberto Corradine

    2012-01-01

    Convento del Santo ECCE-HOMO, Síntesis histórica y esbozo-analítico/ Alberto Corradine. No. 6-7, 1971-1972; p. 57-68. El autor describe y analiza el estilo arquitectónico del ECCE-HOMO señalando especialmente la influencia del estilo mudejar venido de España en el siglo XVII. 

  11. The CSNI/PWG-1 international task group on ECCS reliability

    Energy Technology Data Exchange (ETDEWEB)

    Sandervag, O.; Riekert, T.; Serkiz, A.; Hyvarinen, J.

    1996-03-01

    A steam line loss-of-coolant accident (LOCA) occurred when a safety relief valve inadvertently opened in the Barseback-2 nuclear power plant. The steam jet stripped fibrous insulation from adjacent pipework. Part of that insulation debris was transported to the wetwell pool and clogged the intake strainers for the drywell spray system after about one hour. Although the incident in itself was not very serious, it revealed a weakness in the defense-in-depth concept which under other circumstances could have led to failure of the emergency core cooling system (ECCS) to provide water to the core. Before the Barseback-2 LOCA, international regulators of nuclear power plants and the nuclear power plant industry had considered safety questions related to strainer clogging as resolved. Many European countries had followed the guidance for strainers in pressurized water reactors (PWRs) contained in United States Nuclear Regulatory Commission`s (USNRC) Regulatory Guide 1.82, Water Sources for Long Term Recirculation Cooling Following a Loss-of-Coolant Accident, 1974. However, data obtained from European experimental programs carried out in the late seventies to determine the performance of strainers indicated that this guide was not adequate. In addition, Swedish plant owners had used this guidance to judge performance of emergency core cooling systems (ECCS) in their plants. Analyses at that time had indicated that strainer clogging, if occurring at all, would at least not occur during the first ten hours after a LOCA. Since operation of the ECCS would be needed for a long time, backflushing capabilities and monitors of pressure drop across the strainers were installed in older Swedish BWR plants with small strainer areas. These actions were judged to be adequate compliance with the revised USNRC Regulatory Guide 1.82, Rev. 1, issued in 1985. Safety questions related to strainer clogging were considered to have been resolved until the incident happened in Barseback-2.

  12. Predicting Clearance Mechanism in Drug Discovery: Extended Clearance Classification System (ECCS).

    Science.gov (United States)

    Varma, Manthena V; Steyn, Stefanus J; Allerton, Charlotte; El-Kattan, Ayman F

    2015-12-01

    Early prediction of clearance mechanisms allows for the rapid progression of drug discovery and development programs, and facilitates risk assessment of the pharmacokinetic variability associated with drug interactions and pharmacogenomics. Here we propose a scientific framework--Extended Clearance Classification System (ECCS)--which can be used to predict the predominant clearance mechanism (rate-determining process) based on physicochemical properties and passive membrane permeability. Compounds are classified as: Class 1A--metabolism as primary systemic clearance mechanism (high permeability acids/zwitterions with molecular weight (MW) ≤400 Da), Class 1B--transporter-mediated hepatic uptake as primary systemic clearance mechanism (high permeability acids/zwitterions with MW >400 Da), Class 2--metabolism as primary clearance mechanism (high permeability bases/neutrals), Class 3A--renal clearance (low permeability acids/zwitterions with MW ≤400 Da), Class 3B--transporter mediated hepatic uptake or renal clearance (low permeability acids/zwitterions with MW >400 Da), and Class 4--renal clearance (low permeability bases/neutrals). The performance of the ECCS framework was validated using 307 compounds with single clearance mechanism contributing to ≥70% of systemic clearance. The apparent permeability across clonal cell line of Madin - Darby canine kidney cells, selected for low endogenous efflux transporter expression, with a cut-off of 5 × 10(-6) cm/s was used for permeability classification, and the ionization (at pH7) was assigned based on calculated pKa. The proposed scheme correctly predicted the rate-determining clearance mechanism to be either metabolism, hepatic uptake or renal for ~92% of total compounds. We discuss the general characteristics of each ECCS class, as well as compare and contrast the framework with the biopharmaceutics classification system (BCS) and the biopharmaceutics drug disposition classification system (BDDCS

  13. The course of nonproliferative diabetic retinopathy following ECCE with posterior chamber IOL implantation.

    Science.gov (United States)

    Raniel, Y; Teichner, Y; Friedman, Z

    1994-01-01

    A prospective study on the effect of ECCE + IOL implantation on the course of diabetic retinopathy (DR) in 59 eyes showed that in one to three years following surgery, progression of DR, including the development of newly formed one, occurred in 28.8% of the eyes. This was more marked in patient with IDDM (IDDM-46%, NIDDM-24%) as well as in eyes with pre-operative BDR (pre-operative BDR-62.5%, no pre-operative BDR-16.3%). Final visual acuity was better in eyes without pre-operative DR as well as in eyes that did not show progression of the retinopathy.

  14. Microorganisms found in secondary cataract material of ECCE patients, a study with SEM and TEM.

    Science.gov (United States)

    Kalicharan, D; Jongebloed, W L; Los, L I; Worst, J G

    1993-01-01

    Globular secondary cataract material, removed from 24 patients with ECCE after ophthalmic cleaning of the anterior capsule, were investigated with SEM and TEM. Besides spherical, somewhat oval shaped bodies of various shape and size comparable with those found in cataractous lenses, (an)aerobic bacteria and yeast cells were found in approximately 70% of the cases, all of them in eyes without intra-ocular inflammation. Probably these bacteria have been transferred from the conjunctiva during IOL.-implantation and were encapsulated without starting an inflammation.

  15. Post-manufacturing, 17-times acceptable raw bit error rate enhancement, dynamic codeword transition ECC scheme for highly reliable solid-state drives, SSDs

    Science.gov (United States)

    Tanakamaru, Shuhei; Fukuda, Mayumi; Higuchi, Kazuhide; Esumi, Atsushi; Ito, Mitsuyoshi; Li, Kai; Takeuchi, Ken

    2011-04-01

    A dynamic codeword transition ECC scheme is proposed for highly reliable solid-state drives, SSDs. By monitoring the error number or the write/erase cycles, the ECC codeword dynamically increases from 512 Byte (+parity) to 1 KByte, 2 KByte, 4 KByte…32 KByte. The proposed ECC with a larger codeword decreases the failure rate after ECC. As a result, the acceptable raw bit error rate, BER, before ECC is enhanced. Assuming a NAND Flash memory which requires 8-bit correction in 512 Byte codeword ECC, a 17-times higher acceptable raw BER than the conventional fixed 512 Byte codeword ECC is realized for the mobile phone application without an interleaving. For the MP3 player, digital-still camera and high-speed memory card applications with a dual channel interleaving, 15-times higher acceptable raw BER is achieved. Finally, for the SSD application with 8 channel interleaving, 13-times higher acceptable raw BER is realized. Because the ratio of the user data to the parity bits is the same in each ECC codeword, no additional memory area is required. Note that the reliability of SSD is improved after the manufacturing without cost penalty. Compared with the conventional ECC with the fixed large 32 KByte codeword, the proposed scheme achieves a lower power consumption by introducing the "best-effort" type operation. In the proposed scheme, during the most of the lifetime of SSD, a weak ECC with a shorter codeword such as 512 Byte (+parity), 1 KByte and 2 KByte is used and 98% lower power consumption is realized. At the life-end of SSD, a strong ECC with a 32 KByte codeword is used and the highly reliable operation is achieved. The random read performance is also discussed. The random read performance is estimated by the latency. The latency is below 1.5 ms for ECC codeword up to 32 KByte. This latency is below the average latency of 15,000 rpm HDD, 2 ms.

  16. [3 1/2 years experiences with ECCE with tunnel incision].

    Science.gov (United States)

    Häberle, H; Anders, N; Antoni, H J; Pham, D T; Wollensak, J

    1997-01-01

    Since January 1992 planned extracapsular cataract extraction (ECCE) is performed routinely with the no-stitch technique at our clinic. To minimize surgically induced astigmatism further, modified wound constructions for planned ECCE with on 1.1-mm tunnel width were evaluated. The follow-up time was up to 3 years postoperatively. For 250 eyes wound closure was performed prospectively either sutureless (n = 70), with a single perpendicular suture (n = 100) or cross sutures (n = 40) at the 12 o'clock position or sutureless in the temporal position (n = 40). The complication rate was 4% (filtering bleb, iris prolapse or transient hypotonia). There were no wound ruptures, but once endophthalmitis was observed. Late mean astigmatism after up to 3 years follow-up for vertical incision was 2.05 +/- 1.16 D (1.01 +/- 0.96 D preoperatively) for sutureless wound closure, 1.63 +/- 1.08 D (0.86 +/- 0.95 D) for perpendicular and 1.76 +/- 0.88 D (0.73 +/- 0.55 D) for cross-sutures. A temporal incision resulted in 0.78 +/- 0.52 D (1.0 +/- 0.69 D) of astigmatism and was only performed on eyes with against the rule astigmatism preoperatively. Surgically induced astigmatism was stabilized early. For with the rule astigmatism preoperatively, a 12 o'clock incision with a perpendicular single suture is recommended and for against the rule astigmatism, a temporal incision.

  17. [Comparison of corneal endothelial cells after ECCE and phacoemulsification of the lens].

    Science.gov (United States)

    Trnavec, B; Cuvala, J; Cernák, A; Vodrázková, E

    1997-08-01

    The authors evaluate the finding on the corneal endothelium before and after operation of cataract. For examination of the endothelium they used a specular microscope SP 1.000 of Topcon Co. The group comprised 64 eyes of 64 patients. The patients were divided at random into two groups. The first group comprised 26 patients, where ECCE was performed. The second group comprised 38 patients and the opaque lens was removed by phacoemulsification. The mean age in the first group was 69.3 years and in the second group 70.7 years. The same viscoelastic material (methylcellulose) was used and the same synthetic lens from PMMA material was implanted into the capsule. The endothelium was examined one day after operation and on the 7th to 10th day after operation. The following parameters were evaluated: density of the endothelial cells in the centre, mean cell size, polymegethism, coefficient of variation, pleomorphism. In the group of patients who had ECCE the loss of endothelial cells was 18.53%, in the group with phacoemulsification of the nucleus the loss was 16.43%. This difference is not statistically significant. After operation in both groups enlargement of the minimal, maximal as well as mean cell size was observed, the coefficient of variation increased while the grade of cell hexagonality decreased. However these differences in endothelial cells were not statistically significant. After operation of cataract not only endothelial cells are lost but also significant changes in cell morphology occur.

  18. A Provably-Secure ECC-Based Authentication Scheme for Wireless Sensor Networks

    Directory of Open Access Journals (Sweden)

    Junghyun Nam

    2014-11-01

    Full Text Available A smart-card-based user authentication scheme for wireless sensor networks (in short, a SUA-WSN scheme is designed to restrict access to the sensor data only to users who are in possession of both a smart card and the corresponding password. While a significant number of SUA-WSN schemes have been suggested in recent years, their intended security properties lack formal definitions and proofs in a widely-accepted model. One consequence is that SUA-WSN schemes insecure against various attacks have proliferated. In this paper, we devise a security model for the analysis of SUA-WSN schemes by extending the widely-accepted model of Bellare, Pointcheval and Rogaway (2000. Our model provides formal definitions of authenticated key exchange and user anonymity while capturing side-channel attacks, as well as other common attacks. We also propose a new SUA-WSN scheme based on elliptic curve cryptography (ECC, and prove its security properties in our extended model. To the best of our knowledge, our proposed scheme is the first SUA-WSN scheme that provably achieves both authenticated key exchange and user anonymity. Our scheme is also computationally competitive with other ECC-based (non-provably secure schemes.

  19. University and place branding: The case of universities located in ECC (European Capital of Culture cities

    Directory of Open Access Journals (Sweden)

    Gábor Rekettye

    2015-03-01

    Full Text Available In the globalising landscape of higher education more and more universities are going international. These universities are facing growing competition, especially in enrolling international students. International competition forces them to use marketing and especially branding activity. University branding requires that the higher education institutions clearly define their differentiating features. One of the most important differentiating features is the place where the institution is located. University and place branding should work together to help the potential students in their decisions to choose the place of their study. The ECC (European Capital of Culture program which started in 1985 has helped many cities to identify their values and to develop their place branding activities. The study examines how the European Capital of Culture designation of the city helped the marketing activities of the universities located in these cities. The study attempts to explore to what extent universities located in ECCs used this special feature of their cities in their international marketing communication. The paper also attempts to analyse the effects the European Capital of Culture title could have on the international student enrolment activity of the concerned universities.

  20. Mechanical interaction of Engineered Cementitious Composite (ECC) reinforced with Fiber Reinforced Polymer (FRP) rebar in tensile loading

    DEFF Research Database (Denmark)

    Lárusson, Lárus Helgi; Fischer, Gregor; Jönsson, Jeppe

    2010-01-01

    This paper introduces a preliminary study of the composite interaction of Engineered Cementitious Composite (ECC), reinforced with Glass Fiber Reinforced Polymer (GFRP) rebar. The main topic of this paper will focus on the interaction of the two materials (ECC and GFRP) during axial loading......, particularly in post cracking phase of the concrete matrix. The experimental program carried out in this study examined composite behavior under monotonic and cyclic loading of the specimens in the elastic and inelastic deformation phases. The stiffness development of the composite during loading was evaluated...

  1. Simulation of strain-hardening in ECC uniaxial test specimen by use of a damage mechanics formulation

    DEFF Research Database (Denmark)

    Dick-Nielsen, Lars; Stang, Henrik; Poulsen, Peter Noe

    2006-01-01

    This paper discusses the considerations for the establishment of a damage model for ECC. Three different length scales are used in the approach for deriving the damage model. On each length scale important phenomena are investigated by use of numerical and analytical calculations. On the micro...... scale it is shown that the cohesive law for a unidirectional fiber reinforced cementitious composite can be found through superposition of the cohesive law for mortar and the fiber bridging curve. On the meso scale I it is shown that the maximum crack opening observed during crack propagation in ECC...

  2. Development of system performance verification test technology for KNGR; optimal design and performance test for DVI of ECC water

    Energy Technology Data Exchange (ETDEWEB)

    Suh, Kune Yull; Yoon, Sang Hyuk; Noh, Sang Woo [Seoul National University, Seoul (Korea); Lee, Il Suk [Kyung Hee University, Seoul (Korea)

    2002-03-01

    In this study, we completed the works for the specific thermal-hydraulic phenomena in the reactor downcomer during a operation of DVI system. The choices for a filed of study are focused on the general abilities and flow behaviors of DVI system in the downcomer, and we intended to be able to suggest the applicable data to the APR1400 for the inclusive, actual, various area from the phenomena caused by the ECC injection to the code analysis of steam flow, ECC bypass and the downcomer water level decrease. 28 refs., 77 figs., 14 tabs. (Author)

  3. Adapted ECC ozonesonde for long-duration flights aboard boundary-layer pressurised balloons

    Science.gov (United States)

    Gheusi, François; Durand, Pierre; Verdier, Nicolas; Dulac, François; Attié, Jean-Luc; Commun, Philippe; Barret, Brice; Basdevant, Claude; Clenet, Antoine; Derrien, Solène; Doerenbecher, Alexis; El Amraoui, Laaziz; Fontaine, Alain; Hache, Emeric; Jambert, Corinne; Jaumouillé, Elodie; Meyerfeld, Yves; Roblou, Laurent; Tocquer, Flore

    2016-12-01

    Since the 1970s, the French space agency CNES has developed boundary-layer pressurised balloons (BLPBs) with the capability to transport lightweight scientific payloads at isopycnic level and offer a quasi-Lagrangian sampling of the lower atmosphere over very long distances and durations (up to several weeks).Electrochemical concentration cell (ECC) ozonesondes are widely used under small sounding balloons. However, their autonomy is limited to a few hours owing to power consumption and electrolyte evaporation. An adaptation of the ECC sonde has been developed specifically for long-duration BLPB flights. Compared to conventional ECC sondes, the main feature is the possibility of programming periodic measurement sequences (with possible remote control during the flight). To increase the ozonesonde autonomy, the strategy has been adopted of short measurement sequences (2-3 min) regularly spaced in time (e.g. every 15 min). The rest of the time, the sonde pump is turned off. Results of preliminary ground-based tests are first presented. In particular, the sonde was able to provide correct ozone concentrations against a reference UV-absorption ozone analyser every 15 min for 4 days. Then we illustrate results from 16 BLBP flights launched over the western Mediterranean during three summer field campaigns of the ChArMEx project (http://charmex.lsce.ipsl.fr): TRAQA in 2012, and ADRIMED and SAFMED in 2013. BLPB drifting altitudes were in the range 0.25-3.2 km. The longest flight lasted more than 32 h and covered more than 1000 km. Satisfactory data were obtained when compared to independent ozone measurements close in space and time. The quasi-Lagrangian measurements allowed a first look at ozone diurnal evolution in the marine boundary layer as well as in the lower free troposphere. During some flight segments, there was indication of photochemical ozone production in the marine boundary layer or even in the free troposphere, at rates ranging from 1 to 2 ppbv h -1, which

  4. Modified ECC ozone sonde for long-duration flights aboard isopicnic drifting balloons

    Science.gov (United States)

    Gheusi, Francois; Durand, Pierre; Verdier, Nicolas; Dulac, François; Attié, Jean-Luc; Commun, Philippe; Barret, Brice; Basdevant, Claude; Clénet, Antoine; Fontaine, Alain; Jambert, Corinne; Meyerfeld, Yves; Roblou, Laurent; Tocquer, Flore

    2015-04-01

    Since few years, the French space agency CNES has developed boundary-layer pressurized balloons (BLPB) with the capability to transport scientific payloads at isopicnic level over very long distances and durations (up to several weeks in absence of navigation limits). However, the autonomy of conventional electrochemical concentration cell (ECC) ozone sondes, that are widely used for tropospheric and stratospheric soundings, is limited to few hours due to power consumption and electrolyte evaporation (owing to air bubbling in the cathode solution). In collaboration with the French research community, CNES has developed a new ozone payload suited for long duration flights aboard BLPB. The mechanical elements (Teflon pump and motor) and the electrochemical cell of conventional ECC sondes have been kept but the electronic implementation is entirely new. The main feature is the possibility of programming periodic measurement sequences -- with possible remote control during the flight. To increase the ozone sonde autonomy, a strategy has been adopted of short measurement sequences (typically 2-3 min) regularly spaced in time (e.g. every 15 min, which is usually sufficient for air quality studies). The rest of the time, the sonde is at rest (pump motor off). The response time of an ECC sonde to an ozone concentration step is below one minute. Consequently, the measurement sequence is typically composed of a one-minute spin-up period after the pump has been turned on, followed by a one- to two-minute acquisition period. All time intervals can be adjusted before and during the flight. Results of a preliminary ground-based test in spring 2012 are first presented. The sonde provided correct ozone concentrations against a reference UV analyzer every 15 minutes during 4 days. Then we illustrate results from 16 BLBP flights launched in the low troposphere over the Mediterranean during summer field campaings in 2012 and 2013 (TRAQA and ChArMEx programmes). BLPB drifting

  5. A Secure ECC-based RFID Mutual Authentication Protocol to Enhance Patient Medication Safety.

    Science.gov (United States)

    Jin, Chunhua; Xu, Chunxiang; Zhang, Xiaojun; Li, Fagen

    2016-01-01

    Patient medication safety is an important issue in patient medication systems. In order to prevent medication errors, integrating Radio Frequency Identification (RFID) technology into automated patient medication systems is required in hospitals. Based on RFID technology, such systems can provide medical evidence for patients' prescriptions and medicine doses, etc. Due to the mutual authentication between the medication server and the tag, RFID authentication scheme is the best choice for automated patient medication systems. In this paper, we present a RFID mutual authentication scheme based on elliptic curve cryptography (ECC) to enhance patient medication safety. Our scheme can achieve security requirements and overcome various attacks existing in other schemes. In addition, our scheme has better performance in terms of computational cost and communication overhead. Therefore, the proposed scheme is well suitable for patient medication systems.

  6. BIOGRAPHY OR A DECLARATION OF PHILOSOPHICAL AMBITION: HOW TO READ ECCE HOMO BY NIETZSCHE

    Directory of Open Access Journals (Sweden)

    Lúcia Schneider Hardt

    2015-06-01

    Full Text Available This article discusses the book Ecce homo, by Nietzsche, defending that the text is an interpretation of the philosopher himself on her own thought, not to give the book a sacred tone, nor to stress his biography, but affirming a dissonant thought that indicates his philosophical ambition. With no constraints, Nietzsche presents his conflicts, passions, deceptions, announcing a tragic dimension of life that is not guided by pessimism, but by happiness of living intensely, understanding suffering as one of the facets of life. His philosophy derives from a life demand, transfigured by an experience that promotes self cultivation and the possibility of “becoming what one really is” through the “applying” of one’s own genealogic method.

  7. General description of KAERI LBLOCA realistic evaluation model (REM) for ECCS evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Yong; Lee, Young Jin; Chung, Bub Dong; Lee, Won Jae [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1994-06-01

    A realistic evaluation model (REM) for LBLOCA licensing calculation is developed for application to pressurezed ligh water reactors. The developmental aim of the KAERI-REM is to provide a systematic methodology that is simple in structure and to used and built upon sound logical reasoning, for improving the code capability to realistically describe the LBLOCA phenomena and for evaluating the associated uncertainties. The method strives to be faithful to the intention of being best-estimate, that is, the method aims to evaluate the best-estimate values and the associated uncertainties while complying to the requirements in the ECCS regulations. As a demonstration, KAERI-REM was applied to quantify the safety margin for LBLOCA for Kori 3 and 4 and appended to this report. (Author) 11 refs., 2 figs., 6 tabs.

  8. Cost-minimization analysis of capsulotomy after ECCE and IOL implantation.

    Science.gov (United States)

    Lertsumitkul, S; La Nauze, J

    1996-06-01

    An economic evaluation of capsulotomy for posterior capsular opacification after extracapsular cataract extraction (ECCE) and intraocular lens (IOL) implantation was carried out using a cost minimization model. This model demonstrates the use of cost comparison to aid the decision making process. A flow-chart of capsulotomy mode, with associated complications, is illustrated. Costs of complications are calculated using assigned probability for each tree. Overall comparative costs are displayed graphically Further, the model is presented using a computer-assisted spreadsheet with an added calculation program. Variables can therefore be adjusted with instantaneous outcomes visually displayed. We present several examples with different sets of variables and find that, in most instances, YAG capsulotomy is a more economical option than surgical capsulotomy. This finding is a relevant finding in planning for eye health programs, particularly in developing countries. We suggest that the model be modified using local parameters in order to provide optimal benefits in similar health programs.

  9. Implementation and verification of different ECC mitigation designs for BRAMs in flash-based FPGAs

    CERN Document Server

    Yang, Zhenlei; Zhang, Zhangang; Liu, Jie; Su, Hong

    2015-01-01

    Embedded RAM blocks (BRAMs) in field programmable gate arrays (FPGAs) are susceptible to single event effects (SEEs) induced by environmental factors such as cosmic rays, heavy ions, alpha particles and so on. As technology scales, the issue will be more serious. In order to tackle this issue, two different error correcting codes (ECCs), the shortened Hamming codes and shortened BCH codes, are investigated in this paper. The concrete design methods of the codes are presented. Also, the codes are both implemented in flash-based FPGAs. Finally, the synthesis report and simulation results are presented in the paper. Moreover, the heavy-ion experiments are performed, the experimental results indicate that the error cross-section using the shortened Hamming codes can be reduced by two orders of magnitude compared with the device without mitigation, and no errors are discovered in the experiments for the device using the shortened BCH codes.

  10. Experiments of ECCS strainer blockage and debris settling in suppression pools

    Energy Technology Data Exchange (ETDEWEB)

    Hecker, G.E.; Johnson, A.B.; Murthy, P.; Padmanabhan

    1996-03-01

    If a rupture occurs in a nuclear power station pipe that leads to or from the reactor pressure vessel, the resultant Loss of Coolant Accident (LOCA) would initiate a chain of events involving complex flow phenomena. In a Boiling Water Reactor (BWR), the steam or liquid pipe break pressurizes the dry well, forcing the inert containment gases and steam through downcomers into the suppression pool, thoroughly mixing any particulates and pipe insulation debris carried with the gas flow to the pool. As the steam flow decreases, its unsteady condensation at the end of the downcomers (Condensation Oscillation and Chugging) produces continued water motion in the suppression pool and downcomers. During the blowdown event, high pressure and then low pressure pumps automatically start injecting water from the suppression pool into the reactor to keep its temperature under control. Proper functioning of this Emergency Core Cooling System (ECCS) is critical for the first 30 minutes or so, before operators have time to consider and align alternative sources of cooling water. A major concern for proper operation of the ECCS is the effect of fragmented insulation and plant particulates on the head loss at pump suction strainers. Sufficient loss could exceed the NPSH margin, causing cavitation with a resultant loss of pump capacity and longevity. The bead loss increases with the mass of debris accumulated on the pump strainers, which in turn is dependent on the debris concentration versus time in the suppression pool. This paper describes two sets of experiments that quantified the strainer head loss. One set of experiments considered the mixing and settling of fibrous insulation debris and fine iron oxide particles in the suppression pool during and after chugging. These tests used a reduced scale facility which duplicated the kinetic energy per unit water volume to define the concentration of the actual materials in the pool versus time.

  11. Interference of sulphur dioxide to balloon-borne ECC ozone sensors over the Valley of Mexico

    Directory of Open Access Journals (Sweden)

    I. Kanda

    2014-01-01

    Full Text Available Abnormal decrease in the ozonesonde sensor signal occurred during air-pollution study campaigns in November 2011 and March 2012 in Mexico City. Sharp drops around 5 km a.s.l. and above were observed in November 2011, and a broad deficit in the convective boundary layer in March 2012. Various circumstantial evidence indicates that the decrease was due to interference of SO2 gas to Electrochemical Concentration Cell (ECC ozone sensors. The sharp drops in November 2011 are considered to be caused by the SO2 plume from the Popocatépetl volcano to the south-east of Mexico City. Response experiments of the ECC sensor to representative atmospheric trace gases showed that only SO2 could generate the observed abrupt drops. The vertical structure of the plume reproduced by a Lagrangian particle diffusion simulation also supported this assumption. The near-ground deficit in March 2012 is considered to be generated by the SO2 plume from the Tula industrial complex to the north-west of Mexico City. Sporadic large SO2 emission is known to occur from this region, and before and at the ozonesonde launching time, large intermittent peaks of SO2 concentration were recorded at the ground-level monitoring stations. The difference between the O3 concentration obtained by ozonesonde and that by UV-based O3 monitor was consistent with the SO2 concentration measured by a UV-based monitor on the ground. The plume vertical profiles estimated by the Lagrangian particle diffusion simulation agreed fairly well with the observed profile. Statistical analysis of the wind field in Mexico City revealed that the Popocatépetl effect is most likely to occur from June to October, and the Tula effect all the year.

  12. Interference of sulphur dioxide to balloon-borne ECC ozone sensors over the Valley of Mexico

    Science.gov (United States)

    Kanda, I.; Basaldud, R.; Horikoshi, N.; Okazaki, Y.; Benítez Garcia, S. E.; Ortínez, A.; Ramos Benítez, V. R.; Cárdenas, B.; Wakamatsu, S.

    2014-01-01

    Abnormal decrease in the ozonesonde sensor signal occurred during air-pollution study campaigns in November 2011 and March 2012 in Mexico City. Sharp drops around 5 km a.s.l. and above were observed in November 2011, and a broad deficit in the convective boundary layer in March 2012. Various circumstantial evidence indicates that the decrease was due to interference of SO2 gas to Electrochemical Concentration Cell (ECC) ozone sensors. The sharp drops in November 2011 are considered to be caused by the SO2 plume from the Popocatépetl volcano to the south-east of Mexico City. Response experiments of the ECC sensor to representative atmospheric trace gases showed that only SO2 could generate the observed abrupt drops. The vertical structure of the plume reproduced by a Lagrangian particle diffusion simulation also supported this assumption. The near-ground deficit in March 2012 is considered to be generated by the SO2 plume from the Tula industrial complex to the north-west of Mexico City. Sporadic large SO2 emission is known to occur from this region, and before and at the ozonesonde launching time, large intermittent peaks of SO2 concentration were recorded at the ground-level monitoring stations. The difference between the O3 concentration obtained by ozonesonde and that by UV-based O3 monitor was consistent with the SO2 concentration measured by a UV-based monitor on the ground. The plume vertical profiles estimated by the Lagrangian particle diffusion simulation agreed fairly well with the observed profile. Statistical analysis of the wind field in Mexico City revealed that the Popocatépetl effect is most likely to occur from June to October, and the Tula effect all the year.

  13. Computer Simulation of the E.C.C.S. Buckling Curve using a Monte-Carlo Method

    NARCIS (Netherlands)

    Strating, J.; Vos, H.

    1973-01-01

    The application of a Monte-Carlo simulation procedure to obtain the distribution function of the maximum load of a hinged column with imperfections is discussed. Buckling tests carried out by the E.C.C.S. on IPE 160 sections have been simulated. Information concerning the column variables is obtaine

  14. Incorporating Indigenous Knowledge and Practice into ECCE: A Comparison of Programs in The Gambia, Senegal and Mali

    Science.gov (United States)

    Soudee, Alicia Ranck

    2009-01-01

    Early Childhood Development (ECD) has emerged as a theme in international and African dialogue on education in recent years. UNESCO's Division of Basic Education Early Childhood promotes an integrated approach to Early Childhood Care and Education (ECCE) policy development and review. The study examines how this is implemented in three West…

  15. Parametric study of the potential for BWR ECCS strainer blockage due to LOCA generated debris. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Zigler, G.; Brideau, J.; Rao, D.V.; Shaffer, C.; Souto, F.; Thomas, W. [Science and Engineering Associates, Inc., Albuquerque, NM (United States)

    1995-10-01

    This report documents a plant-specific study for a BWR/4 with a Mark I containment that evaluated the potential for LOCA generated debris and the probability of losing long term recirculation capability due ECCS pump suction strainer blockage. The major elements of this study were: (1) acquisition of detailed piping layouts and installed insulation details for a reference BWR; (2) analysis of plant specific piping weld failure probabilities to estimate the LOCA frequency; (3) development of an insulation and other debris generation and drywell transport models for the reference BWR; (4) modeling of debris transport in the suppression pool; (5) development of strainer blockage head loss models for estimating loss of NPSH margin; (6) estimation of core damage frequency attributable to loss of ECCS recirculation capability following a LOCA. Elements 2 through 5 were combined into a computer code, BLOCKAGE 2.3. A point estimate of overall DEGB pipe break frequency (per Rx-year) of 1.59E-04 was calculated for the reference plant, with a corresponding overall ECCS loss of NPSH frequency (per Rx-year) of 1.58E-04. The calculated point estimate of core damage frequency (per Rx-year) due to blockage related accident sequences for the reference BWR ranged from 4.2E-06 to 2.5E-05. The results of this study show that unacceptable strainer blockage and loss of NPSH margin can occur within the first few minutes after ECCS pumps achieve maximum flows when the ECCS strainers are exposed to LOCA generated fibrous debris in the presence of particulates (sludge, paint chips, concrete dust). Generic or unconditional extrapolation of these reference plant calculated results should not be undertaken.

  16. Secure Cluster Based Routing Using SAT/ILP Techniques and ECC EL-Gamal Threshold Cryptography in MANET

    Directory of Open Access Journals (Sweden)

    Mr. P. Kanagaraju. Me, (Ph. D

    2014-03-01

    Full Text Available The Elliptic curve cryptography ( ECC a promising and important because it requires less computing power, bandwidth, and also the memory when comparing to other cryptosystems The clustering algorithm using the Integer Linear Programming (ILP and Boolean Satisfiability (SAT solvers. These improvements will secure the application of SAT and ILP techniques in modeling composite engineering problem that is the Clustering Problem in Mobile Ad-Hoc Networks (MANETs. The Clustering Problem in MANETs consists of selecting the most appropriate nodes of a given MANET topology as clusterheads, and ensuring that regular nodes are related to clusterheads such that the lifetime of the network is maximized. In which, discussing SAT/ILP techniques for clustering techniques and ECC El Gamal Threshold Cryptography for the security. Through our implementation, explored the possibility of using ECCEG-TC in MANETs.

  17. Ageing and COPD affect different domains of nutritional status: the ECCE study.

    Science.gov (United States)

    Battaglia, S; Spatafora, M; Paglino, G; Pedone, C; Corsonello, A; Scichilone, N; Antonelli-Incalzi, R; Bellia, V

    2011-06-01

    Chronic obstructive pulmonary disease (COPD) and ageing may contribute to malnutrition. We aimed to explore whether COPD and ageing determine malnutrition in different manners. 460 stable COPD outpatients (376 males and 84 females) from the Extrapulmonary Consequences of COPD in the Elderly (ECCE) study database were investigated (age 75.0±5.9 yrs; forced expiratory volume in 1 s 54.7±18.3% predicted). Nutritional status was evaluated using the Mini Nutritional Assessment® (MNA) questionnaire. From the MNA, three scores exploring the domains of the nutritional status were calculated: body composition, energy intake and body functionality scores. Global Initiative for Chronic Obstructive Lung Disease (GOLD) stages were negatively correlated with five MNA items exploring mobility, patient's perception of own nutrition and health status, and arm and calf circumferences (lowest Spearman's rho (rs)=-0.011; highest p=0.039). GOLD stages were independently correlated with body composition and body functionality scores (model r2=0.073). Age was negatively correlated with four MNA items exploring loss of appetite, fluid intake, mobility and autonomy in daily life (lowest rs=-0.013; highest p=0.030). Age was independently correlated with body functionality score (model r2=0.037). Severe COPD and ageing are independent and probably concurrent conditions leading to malnutrition. The MNA questionnaire allows a valuable insight into the complexity of components of nutritional status and may provide useful clues for treatment strategies.

  18. [Visco-hydraulic irrigation of the lens cortex. A safe ECCE method].

    Science.gov (United States)

    Friedburg, D

    1994-12-01

    The safe and effective Hydrojet nucleus expression (Klin Monatsbl Augenheilkd 1993; 202:288-291) should be completed by a safe non traumatic and easy to perform method of cortex removal. OPERATION TECHNIQUE: 8-mm tunnel incision, spiral capsulorhexis, hydrodissection and viscodissection of the nucleus, hydrojet nucleus expression. The lens cortex can be separated from the lens capsule by injection of hydroxypropylmethylcellulose (Metho), the viscoelastic substance acts as a wedge to separate the cortex from the capsule step by step. Finally the cortex is expressed by the injection of Metho. The capsule remains so clean, that often polishing is not necessary. PMMA lenses with an over all diameter of 10 or 11-mm and 7-mm optics were implanted. In 100 consecutive cases complications which occurred intraoperatively or within the following 2 days were listed. The following complications occurred: Hyphaema (2x, the blood disappeared spontaneously within 4-5 days), small cortex flake in the anterior chamber (2x), rhexis rim not intact (1x, nevertheless exact lens centration in the bag). No lesion of the capsule/zonule diaphragm, no fibrin reaction, no corneal edema. The method described is a safe method for ECCE. Capsulorhexis and tunnel incision are required. The method does not need any high technology equipment.

  19. Estimated net value and uncertainty for automating ECCS switchover at PWRs

    Energy Technology Data Exchange (ETDEWEB)

    Walsh, B.; Brideau, J.; Comes, L.; Darby, J.; Guttmann, H.; Sciacca, F.; Souto, F.; Thomas, W.; Zigler, G. [Science and Engineering Associates, Inc., Albuquerque, NM (United States)

    1996-02-01

    Question for resolution of Generic Safety Issue No. 24 is whether or not PWRs that currently rely on a manual system for ECCS switchover to recirculation should be required to install an automatic system. Risk estimates are obtained by reevaluating the contributions to core damage frequencies (CDFs) associated with failures of manual and semiautomatic switchover at a representative PWR. This study considers each separate instruction of the corresponding emergency operating procedures (EOPs), the mechanism for each control, and the relation of each control to its neighbors. Important contributions to CDF include human errors that result in completely coupled failure of both trains and failure to enter the required EOP. It is found that changeover to a semiautomatic system is not justified on the basis of cost-benefit analysis: going from a manual to a semiautomatic system reduces the CDF by 1.7 {times} 10{sup {minus}5} per reactor-year, but the probability that the net cost of the modification being less than $1, 000 per person-rem is about 20% without license renewal. Scoping analyses, using optimist assumptions, were performed for a changeover to a semiautomatic system with automatic actuation and to a fully automatic system; in these cases the probability of a net cost being less than $1,000/person-rem is about 50% without license renewal and over 95% with license renewal.

  20. Comparison of results and complications following combined ECCE-trabeculectomy versus small-incision-trabeculectomy and posterior chamber lens implantation.

    Science.gov (United States)

    Wedrich, A; Menapace, R; Hirsch, U; Papapanos, P; Derbolav, A; Ries, E

    To compare the efficacy and complication rate of two standard cataract extraction techniques with different incision lengths when combined with trabeculectomy. 54 eyes after combined ECCE, posterior chamber lens implantation and trabeculectomy (ECCE-group) are compared with 49 eyes following phacoemulsification, trabeculectomy and implantation of a folded flexible posterior chamber lens (small-incision group). Minimum follow-up was 24 months. Glaucoma control was achieved in all eyes of both groups. There was a tendency towards a higher number of patients without therapy in the small-incision group (82% versus 65%, p = 0.07). Final mean IOP (14.2 +/- 3.0 mmHg versus 15.5 +/- 2.7 mmHg, p = 0.02) and mean therapy index (0.2 +/- 0.5 versus 0.4 +/- 0.6, p = 0.03) were significantly lower in the small-incision group. Postoperative complications such as severe fibrin effusion (41% versus 18%, p = 0.018), early postoperative IOP rises > 25 mmHg (18% versus 2%, p = 0.009), filtering bleb scarring (63% versus 8%, p ECCE-group. With the decrease of the incision size necessary for the cataract extraction a reduction of postoperative complications and better functional results are achieved in combined cataract/glaucoma surgery.

  1. Comparison of allele frequency for HLA-DR and HLA-DQ between patients with ECC and caries-free children

    Directory of Open Access Journals (Sweden)

    Bagherian A

    2008-03-01

    Full Text Available Background: Early childhood caries (ECC is one of the most common diseases of childhood. The etiology of ECC is multifactorial and both genetic and environmental factors play important roles in the pathogenesis of the disease. Genetic variations in the hosts may contribute to changes in the risk for dental caries. Genetic factors such as human leukocyte antigen (HLA have recently been suggested as a predisposing factor. Aim: The aim of this study was to look for an association between HLA-DRB1 and HLA-DQB1 with ECC for developing new strategies for the diagnosis as well as the prevention of the disease. Design: In this study, we extracted the genomic DNAs from whole blood samples of 44 patients with ECC and 35 caries-free children by the salting-out method. We amplified the genomic DNA by PCR-SSP and then HLA-typing was performed for all alleles. Results: The results revealed a significant increase in the frequency of HLA-DRB1FNx0104 in the patient group (P = 0.019. The odds ratio for this allele was detected to be 10. The frequency of HLA-DQB1 alleles was not significantly different between the two groups. Conclusion: The above results suggest that HLA-DRB1FNx0104 is associated with the susceptibility to ECC. Thus HLA-DRB1FNx0104 detection as a molecular marker for early diagnosis of ECC may be recommended.

  2. Experimental and theoretical study for the multidimensional phenomena of the ECC bypass in the DVI system downcomer during reflood phase of the LBLOCA

    Energy Technology Data Exchange (ETDEWEB)

    Song, Chul Hwa; Cho, Hyoung Kyu; Yun, Byong Jo; Euh, Dong Jin; Kwon, Tae Soon

    2005-02-01

    In the present study, a new scaling methodology, 'Modified Linear Scaling', was developed which can reproduce the multidimensional ECC behaviors in the DVI system downcomer and its applicability was experimentally and analytically evaluated. An exploratory test was performed to identify the mechanism and flow patterns of the ECC bypass and to investigate the effect of the downcomer geometry on the ECC bypass. Based on the observation results, an analysis for the two-dimensional film flow was conducted, which was found to the dominant flow regime in the DVI system downcomer and it introduced the Wallis parameters as the major scaling parameters of the direct ECC bypass. From the experiments and analysis, scaling requirements of the multidimensional phenomena were derived that the aspect ratio of the test facility and the film spreading width of the ECC should be preserved in the proto and reduced model. The modified linear scaling was developed which can satisfy the scaling requirements from the two-dimensional two-fluid equations and some important phenomena, which may not be fully represented by the equations, were additionally analyzed as a local phenomena scaling. The applicability of the scaling methodology is experimentally and analytically evaluated from the separate effect tests for the direct ECC bypass and sweep-out in various scales of the test sections and the developed analytical models.

  3. Prevalence and socio-behavioral influence of early childhood caries, ECC, and feeding habits among 6 – 36 months old children in Uganda and Tanzania

    Directory of Open Access Journals (Sweden)

    Masumo Ray

    2012-07-01

    Full Text Available Abstract Background Early childhood caries (ECC is a serious problem that has remained unexplored in sub-Saharan Africa. This study aimed to identify possible socio-behavioral correlates of ECC focusing 6–36 months old children and their caretakers. Methods Cross sectional studies were conducted in a high fluoride rural area, Manyara, Tanzania and a low fluoride urban area, Kampala, Uganda. Totals of 1221 and 816 child - caretaker pairs attending health care facilities for growth monitoring were recruited in Manyara and Kampala, respectively. All caretakers completed face to face interviews at the health care facility. Children underwent oral clinical examination whereby ECC and Enamel hypoplasia were recorded using the dmft (WHO 1997 and the DDE index (FDI 1992. Results The prevalence of ECC was 3.7% in Manyara and 17.6% in Kampala. According to multiple logistic regression analyses, received oral health information from health worker was the strongest determinant of ECC in Manyara, adjusted OR 0.3, 95% CI 0.09 – 0.93. In Kampala, visible plaque, high sugar intake and presence of enamel hypoplasia associated with ECC, adjusted ORs 2.8 (95% CI 1.61- 4.95, 3.0 (95% CI 1.39 – 6.34 and 2.3 (95% CI 1.36 - 3.95. Conclusion Oral health education aimed at caretakers of 6–36 months, including health care workers’ information regarding the detrimental consequences for oral health of frequent sugar consumption and poor oral hygiene is important for prevention of ECC in Tanzania and Uganda.

  4. R&D Plan for RISMC Industry Application #1: ECCS/LOCA Cladding Acceptance Criteria

    Energy Technology Data Exchange (ETDEWEB)

    Szilard, Ronaldo Henriques [Idaho National Lab. (INL), Idaho Falls, ID (United States); Zhang, Hongbin [Idaho National Lab. (INL), Idaho Falls, ID (United States); Epiney, Aaron Simon [Idaho National Lab. (INL), Idaho Falls, ID (United States); Tu, Lei [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-04-01

    The Nuclear Regulatory Commission (NRC) is finalizing a rulemaking change that would revise the requirements in 10 CFR 50.46. In the proposed new rulemaking, designated as 10 CFR 50.46c, the NRC proposes a fuel performance-based equivalent cladding reacted (ECR) criterion as a function of cladding hydrogen content before the accident (pre-transient) in order to include the effects of higher burnup on cladding performance as well as to address other technical issues. A loss of operational margin may result due to the more restrictive cladding embrittlement criteria. Initial and future compliance with the rule may significantly increase vendor workload and licensee costs as a spectrum of fuel rod initial burnup states may need to be analyzed to demonstrate compliance. The Idaho National Laboratory (INL) has initiated a project, as part of the DOE Light Water Reactor Sustainability Program (LWRS), to develop analytical capabilities to support the industry in the transition to the new rule. This project is called the Industry Application 1 (IA1) within the Risk-Informed Safety Margin Characterization (RISMC) Pathway of LWRS. The general idea behind the initiative is the development of an Integrated Evaluation Model (IEM). The motivation is to develop a multiphysics framework to analyze how uncertainties are propagated across the stream of physical disciplines and data involved, as well as how risks are evaluated in a LOCA safety analysis as regulated under 10 CFR 50.46c. This IEM is called LOTUS which stands for LOCA Toolkit for US, and it represents the LWRS Program’s response to the proposed new rule making. The focus of this report is to complete an R&D plan to describe the demonstration of the LOCA/ECCS RISMC Industry Application # 1 using the advanced RISMC Toolkit and methodologies. This report includes the description and development plan for a RISMC LOCA tool that fully couples advanced MOOSE tools already in development in order to characterize and optimize

  5. Prevention of early childhood caries (ECC) through parental toothbrushing training and fluoride varnish application: a 24-month randomized controlled trial.

    Science.gov (United States)

    Jiang, Emily Ming; Lo, Edward Chin Man; Chu, Chun Hung; Wong, May Chun Mei

    2014-12-01

    To investigate the effectiveness of hands-on training in parental toothbrushing, with or without semi-annual applications of 5% sodium fluoride varnish in preventing ECC. Study was conducted in Hong Kong where water is optimally fluoridated. Children aged 8-23 months were recruited and randomly allocated to one of three groups: Gp 1 - control, one-off oral health education talk to parents; Gp 2 - oral health education talk and parental toothbrushing training, reinforced every 6 months; Gp 3 - semi-annual application of fluoride varnish onto child's teeth in addition to the intervention provided to Gp 2. Clinical examinations of the children and interviews were conducted at baseline and after 24 months to assess the children's dental caries status and toothbrushing behaviour. Out of the 450 child-parent dyads recruited at baseline, 415 (92%) remained after 24 months. At baseline, 2% of the children had non-cavitated enamel caries lesions and the mean dmft score was 0.03 ± 0.24. Most of the children did not have daily parental toothbrushing (65-73%) and self toothbrushing (86-90%). At 24-month follow-up, including both non-cavitated and cavitated carious lesions, the incidences of ECC in Gp 1 to Gp 3 were 11.9%, 11.8%, and 17.5%, respectively (p>0.05); and the mean new dmft scores in Gp 1 to Gp 3 were 0.3, 0.2, and 0.3, respectively (p>0.05). Proportions of parents who practiced parental toothbrushing twice daily were 62.7%, 60.4%, and 65.7% in Gp 1 to Gp 3, respectively (p>0.05). In a water fluoridated area, hands-on training in parental toothbrushing, with or without semi-annual application of 5% sodium fluoride varnish may not have additional effect on preventing ECC in young children with low risk of dental caries compared to provision of oral health education to parents. In a water fluoridated area, provision of individual oral health education to parents may be sufficient for preventing ECC in young children below age 3. Supplemental training in parental

  6. Effect of sucrose concentration on sucrose-dependent adhesion and glucosyltransferase expression of S. mutans in children with severe early-childhood caries (S-ECC).

    Science.gov (United States)

    Zhao, Wei; Li, Wenqing; Lin, Jiacheng; Chen, Zhuoyu; Yu, Dongsheng

    2014-09-09

    Sucrose, extracellular polysaccharide, and glucosyltransferases (GTFs) are key factors in sucrose-dependent adhesion and play important roles in the process of severe early-childhood caries (S-ECC). However, whether sucrose concentration regulates gtf expression, extracellular polysaccharide synthesis, and sucrose-dependent adhesion is related to the different genotypes of S. mutans isolated from ECC in children and still needs to be investigated. In this study, 52 strains of S. mutans were isolated from children with S-ECC and caries-free (CF) children. Water-insoluble glucan (WIG) synthesis was detected by the anthrone method, adhesion capacity by the turbidimetric method, and expression of gtf by RT-PCR in an in vitro model containing 1%-20% sucrose. The genotypes of S. mutans were analyzed by AP-PCR. The results showed that WIG synthesis, adhesion capacity, and gtf expression increased significantly when the sucrose concentration was from 1% to 10%. WIG synthesis and gtfB as well as gtfC expression of the 1% and 5% groups were significantly lower than those of the 10% and 20% groups (p S. mutans detected from individuals in the S-ECC group exhibited a significant difference in diversity compared with those from CF individuals (p S. mutans, and the 10% sucrose level can be seen as a "turning point" and essential factor for the prevention of S-ECC.

  7. Low-Profile Dual-Wideband MIMO Antenna with Low ECC for LTE and Wi-Fi Applications

    Directory of Open Access Journals (Sweden)

    Gye-Taek Jeong

    2014-01-01

    Full Text Available This paper presents a low-profile dual-wideband multiple input multiple output (MIMO antenna with low envelop correlation coefficient (ECC for long-term evolution (LTE and wireless fidelity (Wi-Fi applications. The antenna covers LTE band 7 and Wi-Fi as well as wireless broadband (Wibro and Worldwide Interoperability for Microwave Access (WiMax (except for the 3.5-GHz band. To aid with integration of a practical mobile terminal, the MIMO antenna elements are placed at appropriate locations by analyzing the surface current distribution and without using any additional isolation techniques. The measured bandwidths with reflection coefficients of 20 dB in the operating frequency ranges of both LTE band 7 and Wi-Fi. Additionally, the calculated ECC is in the range 0.005<ρ<0.025, which is considerably lower than the ρ<0.5 required for MIMO applications. The measured radiation patterns are appropriate for mobile terminals, and omnidirectional radiation patterns are obtained.

  8. AN ANALYSIS OF STUDENTS’ SPEAKING ABILITY IN ENGLISH CONVERSATION CLUB (ECC PROGRAM AT THE 3rd SEMESTER

    Directory of Open Access Journals (Sweden)

    M. Fadhly Farhy Abbas

    2017-07-01

    Full Text Available This research is based on students’ speaking ability who had followed the EnglishConversation Club (ECC program especially for the third semester of English Department. Thepurpose of this study was to analyze the students’ speaking ability at the 3rd semester in the EnglishConversation Club FKIP UNILAK Pekanbaru. The type of the research was mixed method in typeof explanatory design. The number of participant was 53 students. The researcher used twoinstruments, those were test and interview. In analyzing the data, it used in descriptive statistics.The result of the analysis showed that the average score of 3rd semester students’ speaking abilitywas 45.42. It can be concluded that the students’ speaking ability was categorized into failed . Thescore of Standard Deviation was 7.02, Variance was 49.30, and Range was 36 points . It meansthat the students’ speaking ability was homogeneous. According to the Z-Score, it can be seen that49.06% students’ ability was higher than average and 50.94% students ability was below theaverage. In conclusion, the students’ ability in learning speaking English was failed, it had beenaffected by some factors, those were lack of vocabulary, grammar and motivation. It was supportedby the interview, eventhough the students’ perception to English Conversation Club (ECCprogram was positive, but in fact, the students’ frequency to speak English was seldom, they wereless practice speaking English everyday.Keywords : Speaking , English Conversation Club (ECC

  9. Design of ECC system based on System Generator%基于System Generator的ECC加解密系统设计

    Institute of Scientific and Technical Information of China (English)

    肖雪芳; 苏航; 雷国伟

    2012-01-01

    Based on several key algorithms of ECC (Elliptic Curve Cryptosystem), each module of the algorithms was designed via Modelsim tool. Then the source codes of each module were generated into its counterpart of ECC system by System Generator, and the modules were grouped into ECC system. Finally, the system was simulated and verified by experimental results.%根据椭圆曲线密码体制的几种关键算法,采用Modelsim仿真工具设计相应的算法模块.然后将各模块代码通过System Generator生成对应的系统模块,再将这些模块搭建成完整的ECC系统.最后对整个ECC系统进行仿真,实验数据进一步验证了该设计的正确性.

  10. Effect of Sucrose Concentration on Sucrose-Dependent Adhesion and Glucosyltransferase Expression of S. mutans in Children with Severe Early-Childhood Caries (S-ECC

    Directory of Open Access Journals (Sweden)

    Wei Zhao

    2014-09-01

    Full Text Available Sucrose, extracellular polysaccharide, and glucosyltransferases (GTFs are key factors in sucrose-dependent adhesion and play important roles in the process of severe early-childhood caries (S-ECC. However, whether sucrose concentration regulates gtf expression, extracellular polysaccharide synthesis, and sucrose-dependent adhesion is related to the different genotypes of S. mutans isolated from ECC in children and still needs to be investigated. In this study, 52 strains of S. mutans were isolated from children with S-ECC and caries-free (CF children. Water-insoluble glucan (WIG synthesis was detected by the anthrone method, adhesion capacity by the turbidimetric method, and expression of gtf by RT-PCR in an in vitro model containing 1%–20% sucrose. The genotypes of S. mutans were analyzed by AP-PCR. The results showed that WIG synthesis, adhesion capacity, and gtf expression increased significantly when the sucrose concentration was from 1% to 10%. WIG synthesis and gtfB as well as gtfC expression of the 1% and 5% groups were significantly lower than those of the 10% and 20% groups (p < 0.05. There were no significant differences between the 10% and 20% groups. The fingerprints of S. mutans detected from individuals in the S-ECC group exhibited a significant difference in diversity compared with those from CF individuals (p < 0.05. Further, the expression of gtfB and gtfC in the S-ECC group was significantly different among the 1- to 5-genotype groups (p < 0.05. It can be concluded that sucrose-dependent adhesion might be related to the diversity of genotypes of S. mutans, and the 10% sucrose level can be seen as a “turning point” and essential factor for the prevention of S-ECC.

  11. Pressure vessel fracture studies pertaining to a PWR LOCA-ECC thermal shock: experiments TSE-1 and TSE-2

    Energy Technology Data Exchange (ETDEWEB)

    Cheverton, R.D.

    1976-09-01

    The LOCA-ECC Thermal Shock Program was established to investigate the potential for flaw propagation in pressurized-water reactor (PWR) vessels during injection of emergency core coolant following a loss-of-coolant accident. Studies thus far have included fracture mechanics analyses of typical PWRs, the design and construction of a thermal shock test facility, determination of material properties for test specimens, and two thermal shock experiments with 0.53-m-OD (21-in.) by 0.15-m-wall (6-in.) cylindrical test specimens. The PWR calculations indicated that under some circumstances crack propagation could be expected and that experiments should be conducted for cracks that would have the potential for propagation at least halfway through the wall.

  12. Industry Application ECCS / LOCA Integrated Cladding/Emergency Core Cooling System Performance: Demonstration of LOTUS-Baseline Coupled Analysis of the South Texas Plant Model

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Hongbin [Idaho National Lab. (INL), Idaho Falls, ID (United States); Szilard, Ronaldo [Idaho National Lab. (INL), Idaho Falls, ID (United States); Epiney, Aaron [Idaho National Lab. (INL), Idaho Falls, ID (United States); Parisi, Carlo [Idaho National Lab. (INL), Idaho Falls, ID (United States); Vaghetto, Rodolfo [Texas A & M Univ., College Station, TX (United States); Vanni, Alessandro [Texas A & M Univ., College Station, TX (United States); Neptune, Kaleb [Texas A & M Univ., College Station, TX (United States)

    2017-06-01

    Under the auspices of the DOE LWRS Program RISMC Industry Application ECCS/LOCA, INL has engaged staff from both South Texas Project (STP) and the Texas A&M University (TAMU) to produce a generic pressurized water reactor (PWR) model including reactor core, clad/fuel design and systems thermal hydraulics based on the South Texas Project (STP) nuclear power plant, a 4-Loop Westinghouse PWR. A RISMC toolkit, named LOCA Toolkit for the U.S. (LOTUS), has been developed for use in this generic PWR plant model to assess safety margins for the proposed NRC 10 CFR 50.46c rule, Emergency Core Cooling System (ECCS) performance during LOCA. This demonstration includes coupled analysis of core design, fuel design, thermalhydraulics and systems analysis, using advanced risk analysis tools and methods to investigate a wide range of results. Within this context, a multi-physics best estimate plus uncertainty (MPBEPU) methodology framework is proposed.

  13. Risk-Informed Margin Management (RIMM) Industry Applications IA1 - Integrated Cladding ECCS/LOCA Performance Analysis - Problem Statement

    Energy Technology Data Exchange (ETDEWEB)

    Szilard, Ronaldo Henriques [Idaho National Lab. (INL), Idaho Falls, ID (United States); Youngblood, Robert [Idaho National Lab. (INL), Idaho Falls, ID (United States); Frepoli, Cesare [Idaho National Lab. (INL), Idaho Falls, ID (United States); Yurko, Joseph P. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Swindlehurst, Gregg [Idaho National Lab. (INL), Idaho Falls, ID (United States); Zhang, Hongbin [Idaho National Lab. (INL), Idaho Falls, ID (United States); Zhao, Haihua [Idaho National Lab. (INL), Idaho Falls, ID (United States); Bayless, Paul D. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Rabiti, Cristian [Idaho National Lab. (INL), Idaho Falls, ID (United States); Alfonsi, Andrea [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, Curtis L. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-04-01

    The U. S. NRC is currently proposing rulemaking designated as “10 CFR 50.46c” to revise the LOCA/ECCS acceptance criteria to include the effects of higher burnup on cladding performance as well as to address some other issues. The NRC is also currently resolving the public comments with the final rule expected to be issued in the summer of 2016. The impact of the final 50.46c rule on the industry will involve updating of fuel vendor LOCA evaluation models, NRC review and approval, and licensee submittal of new LOCA evaluations or reanalyses and associated technical specification revisions for NRC review and approval. The rule implementation process, both industry and NRC activities, is expected to take 5-10 years following the rule effective date. The need to use advanced cladding designs is expected. A loss of operational margin will result due to the more restrictive cladding embrittlement criteria. Initial and future compliance with the rule may significantly increase vendor workload and licensee cost as a spectrum of fuel rod initial burnup states may need to be analyzed to demonstrate compliance. Consequently there will be an increased focus on licensee decision making related to LOCA analysis to minimize cost and impact, and to manage margin.

  14. [Pre- and postoperative corneal topography after combined single suture and running suture in ECCE. An analysis using the video keratoscope].

    Science.gov (United States)

    Schickel, B; Holschbach, A; Strobel, J

    1993-12-01

    In a prospective study with 45 patients undergoing extracapsular cataract extraction (ECCE) with implantation of posterior chamber lens, curvature measurements of the cornea by means of computerized videokeratoscope were taken postoperatively. Analysis of the corneal shape on color-coded topographic maps of astigmatism showed an hourglass-shaped formation in all patients with a main axis in the sense of general astigmatism. Within a 3-mm zone (optical zone) the steepest meridian in all eyes was 96.1 +/- 13.3 degrees with an astigmatism of +4.4 +/- 2.1 D (1st postoperative day). Postoperatively we found that 35.6% of the patients examined had irregular astigmatism that could not be corroborated by the readings from the Javal ophthalmometer. An irregular astigmatism, corneal topographic analysis reveals regions peripheral to the center with a peak corneal refractive power of +43.8 +/- 1.4 D. In contrast to the conventional methods (for example, Javal ophthalmometer, autokeratometer), computerized videokeratoscope analysis provides additional and useful information on the corneal topography after intraocular operations.

  15. Conductivity probes for two-phase flow pattern determination during emergency core cooling (ECC) injection experiments at the COCO facility (PHDR)

    Energy Technology Data Exchange (ETDEWEB)

    Prasser, H.M. (Research Centre Rossendorf, Dresden (Germany)); Kueppers, L. (Nuclear Research Centre Karlsruhe (Germany)); May, R. (Fraunhofer Inst. for Nondestructive Testing, Dept. Acoustical Methods for Nondestructive Testing, Evaluation and Quality Assurance, Dresden (Germany))

    1992-07-01

    The paper describes the use of needle-shaped conductivity probes for two-phase flow pattern determination during simulated ECC. The first results appear promising and the use of such probes as additional instrumentation can be envisaged in the future on power reactors, e.g. for the control of water level, once some improvements have been achieved, in particular regarding the stability of the probe. (orig.)

  16. Phacoemulsification with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract.

    Science.gov (United States)

    de Silva, Samantha R; Riaz, Yasmin; Evans, Jennifer R

    2014-01-29

    Age-related cataract is one of the leading causes of blindness worldwide. Therefore, it is important to establish the most effective surgical technique for cataract surgery. The aim of this review is to examine the effects of two types of cataract surgery for age-related cataract: phacoemulsification and extracapsular cataract extraction (ECCE). We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2013, Issue 4), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to May 2013), EMBASE (January 1980 to May 2013), Latin American and Caribbean Literature on Health Sciences (LILACS) (January 1982 to May 2013), Web of Science Conference Proceedings Citation Index - Science (CPCI-S) (January 1970 to May 2013), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the WHO International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 13 May 2013. We included randomised controlled trials of phacoemulsification compared to ECCE for age-related cataract. Two authors independently selected and assessed all studies. We defined two primary outcomes: 'good functional vision' (presenting visual acuity of 6/12 or better) and 'poor visual outcome' (best corrected visual acuity of less than 6/60) at three and 12 months after surgery. We also collected data on intra and postoperative complications, and the cost of the procedures. We included 11 trials in this review with a total of 1228 participants, ranging from age 45 to 94. The studies were generally at unclear risk of bias due to poorly reported trial methods. No study reported presenting visual acuity, so we report both uncorrected (UCVA) and best corrected visual acuity (BCVA

  17. Prevalence of candida albicans in dental plaque and caries lesion of early childhood caries (ECC) according to sampling site

    Science.gov (United States)

    Ghasempour, Maryam; Sefidgar, Seyed Ali Asghar; Eyzadian, Haniyeh; Gharakhani, Samaneh

    2011-01-01

    Background: Candida albicans may have cariogenic potential but its role in caries etiology has not been established. The aim of this study was to determine candida albicans in supragingival dental plaque and infected dentine of cervical and proximal in early childhood caries (ECC). Methods: This cross-sectional study was carried out on 6o children aged 2-5 years, which were divided into 3 groups: children with at least one cervical caries; children with at least one proximal caries and caries-free. The infected dentine was collected from cervical and proximal caries lesions and plaque samples were collected from the three groups in order to compare the frequency of candida albicans in the collected sites. All samples were cultured in Sabouraud and CHROMagar medium and the cases that were positive for candida albicans were cultured in germ tube. Data were collected and analyzed. Results: The mean age of the children was 3.9 years. From 100 samples, candida albicans samples were isolated in 55%, mold fungi were found in 29% cases and there was no fungal growth in 16% of the samples. In plaque samples, candida albicans were found in 15% of caries-free samples, 20% of the proximal and 80% of the cervical caries. In samples extracted from the caries, candida albicans were found in 60% of the proximal and 100% of the cervical caries. Mothers with university educational level had children with more cervical decays, caries free and proximal caries, respectively. Conclusion: The results showed that prevalence of Candida albicans in dental plaque and caries lesions of children with early childhood caries were relatively high and the prevalence was higher in cervical caries group. PMID:24551436

  18. SOFTWARE IMPLEMENTATION OF AN ECC ENCRYPTION ALGORITHM OVER PRIME FIELDS%素数域上ECC加密算法的软件实现

    Institute of Scientific and Technical Information of China (English)

    刘磊

    2012-01-01

    椭圆曲线密码是目前公认的每比特安全性最高的密码体制,它具有安全性高、速度快、密钥短、实现时所需占用资源少等优点,非常适合应用于银行结算、电子商务和通信等领域,因此研究椭圆曲线密码的实现有重要意义.首先讨论椭圆曲线密码基本理论,然后介绍安全椭圆曲线选取方法以及经典的ECC加密算法,最后在Core(TM)2 Duo CPU E7500 2.93GHz实验平台上用标准C语言对该算法进行实现,验证该加密算法的可行性.%The elliptic curve cryptography (ECC) is generally recognised at present as the most secure encryption system, which provides highest level of security strength-per-bit and has many advantages such as higher safety property, faster speed, shorter key lengths and fewer computational resources for implementation, and is very suitable for the sectors of bank settlement, e-commerce and communication. Therefore it is of significance to study the software implementation of ECC encryption algorithm. In this paper, we first introduce the basic theory of elliptic curve cryptography, and then describe the way to select a secure elliptic curve and the classic ECC encryption algorithm. Finally, we implement this algorithm in C and the assembler on a Core(TM)2 Duo CPU E75OO 2.93GHz workstation, and testify the feasibility of it.

  19. 基于ECC的认证协议及动态密钥管理方案%The Authentication Protocol and Dynamic Key Management Based on ECC

    Institute of Scientific and Technical Information of China (English)

    曹阳

    2009-01-01

    针对当前无线网络中认证和密钥管理存在的安全缺陷,通过对椭圆曲线密码体制(ECC)的研究,结合ECMOV密钥协商协议和IEEE 802.1X扩展认证协议EAP-TLS及X.509证书,提出了一种在无线局域网中基于ECC的双向认证协议及密钥管理方案.

  20. Preliminary analysis of modeling of Pars and steam injectors to support long-term operation of LWR passive ECCS using a best estimate thermal-hydraulics code

    Energy Technology Data Exchange (ETDEWEB)

    Morales S, J. B.; Sanchez J, J. [UNAM, Facultad de Ingenieria, Circuito Interior s/n, Ciudad Universitaria, 04510 Mexico D. F. (Mexico); Espinosa P, G., E-mail: jaimebmoraless@gmail.co [Universidad Autonoma Metropolitana, Unidad Iztapalapa, Av. San Rafael Atlixco No. 186, Col. Vicentina, 09340 Mexico D. F. (Mexico)

    2010-10-15

    In order to control the amount of hydrogen produced, during the chemical reaction of steam and strongly overheated zirconium in a LWR severe accident, several control methos have been proposed. In a considerable number of nuclear power plants the initial preferred solution was either the use of an inert containment atmosphere or the use of igniters. However, the use of Pars (Passive autocatalytic recombiners) has been considered an important addition to this set of H{sub 2} controls. Pars have appealing features such as, low maintenance, do not require active components to start operation, and can initiate the H{sub 2} and O{sub 2} recombination at low concentrations. However, under certain conditions these Pars may trigger H{sub 2} ignition leading to deflagration s with possible containment damages. Combustions, poisons and liquid may inhibit or reduce the Pars operation. Advanced LWR designs (generation III + and IV) are also considering the use of Pars as a supporting system to the long term operation of their passive ECCS (Emergency Core Cooling Systems) because they may transport the energy of containment H{sub 2} and O{sub 2} gases to external sinks. Even when the ECCS of modern nuclear power plants are designed to maintain containment conditions under established limits, there are small amounts of O{sub 2} and H{sub 2} produced mainly by H{sub 2}O radiolysis, and after several days of containment isolation, these gases may accumulate in places where the possibility of a H{sub 2} deflagration increases. Therefore, the use of Pars looks initially as an interesting solution to long-term H{sub 2} control during a Dba. However, the H{sub 2} and O{sub 2} recombination is an exothermic process resulting in additional steam and energy releases to the containment. In order to avoid a direct deposition of the steam and energy (Pars produced) into the containment atmosphere, we propose to use them to operate steam injectors that can bring cold water to replenish ECCS

  1. Bias in peak clad temperature predictions due to uncertainties in modeling of ECC bypass and dissolved non-condensable gas phenomena

    Energy Technology Data Exchange (ETDEWEB)

    Rohatgi, U.S.; Neymotin, L.Y.; Jo, J.; Wulff, W. (Brookhaven National Lab., Upton, NY (USA))

    1990-09-01

    This report describes a general method for estimating the effect on the Reflood Phase PCT from systematic errors (biases) associated with the modelling of the ECCS and dissolved nitrogen, and the application of this method in estimating biases in the Reflood Phase PCT (second PCT) predicted by the TRAC/PF1/MOD1, Version 14.3. The bias in the second PCT due to the uncertainty in the existing code models for ECCS related phenomena is {minus}19{degree}K ({minus}34{degree}F). The negative bias implies that the code models for this phenomena are conservative. The bias in the second PCT due to the lack of modelling of dissolved N{sub 2} in the code is estimated to be 9.9{degree}K (17.8{degree}F). The positive bias implies that the absence of dissolved N{sub 2} model makes the code prediction of PCT non-conservative. The bias estimation in this report is a major exception among all other uncertainty and bias assessments performed in conjunction with the CSAU methodology demonstration, because this bias estimation benefitted from using full-scale test data from the full-scale Upper Plenum Test Facility (UPTF). Thus, the bias estimates presented here are unaffected by scale distortions in test facilities. Data from small size facilities were also available and an estimate of bias based on these data will be conservative. 35 refs., 18 figs., 5 tabs.

  2. Nietzsche como destino da filosofia e da humanidade? interpretação contextual do § 1 do capítulo "por que sou um destino", de ecce homo

    Directory of Open Access Journals (Sweden)

    Werner Stegmaier

    2010-01-01

    Full Text Available The following translation is a reduced and revised version of the paper Schicksal Nietzsche? Zu Nietzsches Selbsteinschätzung als Schicksal der Philosophie und der Menschheit (Ecce Homo, Warum ich ein Schicksal bin §1" - originally published in Nietzsche-Studien 37 (2008 - which was specially prepared to be presented in lecture organized by the Grupo de Pesquisa Spinoza & Nietzsche (Spinoza & Nietzsche research group - SpiN, in the Universidade Federal do Rio de Janeiro (Rio de Janeiro's Federal University, on September 14, 2009. In the text, the autor employs his own philological-hermeneutical methodology, which is called contextual interpretation, in the purpose to clarify the concepts of the first aphorism from "Why I am a destiny", from Ecce Homo, in its own context, in the context of Ecce Homo and in the context of the entire work from Nietzsche.

  3. Nietzsche como destino da filosofia e da humanidade? interpretação contextual do § 1 do capítulo "por que sou um destino", de ecce homo

    Directory of Open Access Journals (Sweden)

    Werner Stegmaier

    2011-01-01

    Full Text Available A tradução que se segue é uma versão resumida e revisada do artigo "Schicksal Nietzsche? Zu Nietzsches Selbsteinschätzung als Schicksal der Philosophie und der Menschheit (Ecce Homo, Warum ich ein Schicksal bin §1" - publicado originalmente em Nietzsche-Studien 37 (2008 - que foi especialmente preparada para ser apresentada em palestra organizada pelo Grupo de Pesquisa Spinoza & Nietzsche (SpiN, na Universidade Federal do Rio de Janeiro, em 14/09/2009. No texto, o autor faz uso de sua própria metodologia filológico-hermenêutica, denominada interpretação contextual, com vistas a esclarecer os conceitos do primeiro aforismo de "por que sou um destino", de Ecce Homo no seu contexto próprio, no contexto de Ecce Homo e no contexto da obra de Nietzsche como um todo.

  4. Manual small incision cataract surgery (MSICS) with posterior chamber intraocular lens versus extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens for age-related cataract.

    Science.gov (United States)

    Ang, Marcus; Evans, Jennifer R; Mehta, Jod S

    2014-11-18

    Age-related cataract is the opacification of the lens, which occurs as a result of denaturation of lens proteins. Age-related cataract remains the leading cause of blindness globally, except in the most developed countries. A key question is what is the best way of removing the lens, especially in lower income settings. To compare two different techniques of lens removal in cataract surgery: manual small incision surgery (MSICS) and extracapsular cataract extraction (ECCE). We searched CENTRAL (which contains the Cochrane Eyes and Vision Group Trials Register) (2014, Issue 8), Ovid MEDLINE, Ovid MEDLINE In-Process and Other Non-Indexed Citations, Ovid MEDLINE Daily, Ovid OLDMEDLINE (January 1946 to September 2014), EMBASE (January 1980 to September 2014), Latin American and Caribbean Health Sciences Literature Database (LILACS) (January 1982 to September 2014), Web of Science Conference Proceedings Citation Index- Science (CPCI-S), (January 1990 to September 2014), the metaRegister of Controlled Trials (mRCT) (www.controlled-trials.com), ClinicalTrials.gov (www.clinicaltrials.gov) and the World Health Organization (WHO) International Clinical Trials Registry Platform (ICTRP) (www.who.int/ictrp/search/en). We did not use any date or language restrictions in the electronic searches for trials. We last searched the electronic databases on 23 September 2014. We included randomised controlled trials (RCTs) only. Participants in the trials were people with age-related cataract. We included trials where MSICS with a posterior chamber intraocular lens (IOL) implant was compared to ECCE with a posterior chamber IOL implant. Data were collected independently by two authors. We aimed to collect data on presenting visual acuity 6/12 or better and best-corrected visual acuity of less than 6/60 at three months and one year after surgery. Other outcomes included intraoperative complications, long-term complications (one year or more after surgery), quality of life, and cost

  5. NAND flash error correction arithmetic based on ECC embedded BCH code%ECC嵌入BCH码的NAND闪存纠错算法

    Institute of Scientific and Technical Information of China (English)

    李进; 金龙旭; 李国宁; 张珂; 傅瑶; 朱鹏

    2012-01-01

    针对现有闪存基于硬件ECC纠错算法的纠错能力差,而基于RS码和BCH码纠错算法的译码耗时长的问题,提出一种适于空间应用的硬件ECC嵌入BCH码的闪存纠错算法.分析了闪存内部组织结构特点及闪存硬件ECC纠错原理,提出了一种嵌入BCH(2084,2048,3)码的闪存纠错算法.采用一种蝶形阵列处理机制来迭代计算BCH校验码.使用地面检测设备对闪存纠错算法进行了试验验证.结果表明,纠错算法能快速稳定、可靠地工作,在Flash单页2 kB/页下,可以纠正24b错误.该纠错提高了空间相机图像存储系统的可靠性.%In order to resolve the problem of the low error correcting capability of hardware ECC and the being time-consuming of decoder based on RS code or BCH code, a NAND flash error correction algorithm based on hardware ECC embedded BCH code for space application was proposed in this paper. First, this paper presents the structural characteristic of flash. Then the principle of data flash hardware ECC was analyzed. An embedded BCH code error correction arithmetic was put fonvard. Then the check code of BCH encoder was calculated by an 8-bit parallel butterfly array processing mechanism. Finally, the verification experiments to NAND controller in the prototype machine of XX-X space multi-spectral camera were carried out. The experiments results showed that the proposed error correction algorithms can operate fast, efficiently, reliably, and stably. The algorithm is able to correct 24b errors in 2 kB/page. The algorithm can improve the reliability of the space camera data storage.

  6. Pressure vessel fracture studies pertaining to a PWR LOCA-ECC thermal shock: experiments TSE-3 and TSE-4 and update of TSE-1 and TSE-2 analysis

    Energy Technology Data Exchange (ETDEWEB)

    Cheverton, R.D.; Bolt, S.E.

    1977-11-04

    The LOCA-ECC Thermal Shock Program was established to investigate the potential for flaw propagation in pressurized-water reactor (PWR) vessels during injection of emergency core coolant following a loss-of-coolant accident. Studies thus far have included fracture mechanics analyses of typical PWRs, the design and construction of a thermal shock test facility, determination of material properties for test specimens, and four thermal shock experiments with 0.53-m-OD (21-in.) by 0.15-m-wall (6-in.) cylindrical test specimens. In the first experiment, initiation was not expected and did not occur, although there was a small amount of subcritical crack growth. In the second experiment, initiation of a semicircular flaw took place as expected; the final length along the surface was about four times the initial length, but there was no radial growth. The third and fourth experiments were similar, and the long axial flaw initiated in good agreement with predictions.

  7. Crack Distribution and Mechanical Performance of Self-healing of Engineered Cementitious Composites(ECC) Materials%工程水泥基材料裂缝分布及自愈合后力学性能

    Institute of Scientific and Technical Information of China (English)

    阚黎黎; 施惠生

    2012-01-01

    Crack distribution, mechanical performance recovery of self-healing engineered cementitious composites(ECC) materials under wet/dry conditioning cycles and nano-identation analyses of the microphases in ECC at 0. 3%, 0. 5%, 1. 0% and 2. 0% pre-loading were investigated. The results suggest that ECC has many characteristics that contribute to self-healing behavior. Majority of ECC cracks are below 30 μm in width. Both ultimate tensile strength and tensile strain capacity of the majority specimens at reloading are higher than the control specimens. The modulus of elasticity, hardness and stiffness of healed products is about 34. 8 Gpa, 1. 6 Gpa and 0. 1 mN/nm respectively.%在0.3%,0.5%,1.0%,2.0%预加拉伸应变破坏下,进行了2种配比、不同龄期的工程水泥基复合材料(ECC)的裂缝分布、干湿循环自愈合后力学性能的恢复及不同物相的纳米压痕测试.结果表明:ECC具有很多有利于裂缝自愈合行为的特性,其裂缝宽度大都在30μm以下,自愈合后,其最终强度及拉伸应变能力均能达到甚至超过对比试件,裂缝自愈合产物的弹性模量约为34.8 GPa,硬度约为1.6 GPa,刚度约为0.1 mN/nm.

  8. Analysis of Related Factors of Children S-ECC%S-ECC儿童乳牙患龋的主要相关因素分析

    Institute of Scientific and Technical Information of China (English)

    樊鲁娜; 王丁

    2013-01-01

    Objective To investigate S-ECC related behavioural and social factors by the way of questionnaire.To provide fundamental data and guidance for oral health care.Methods Oral examination and questionnaire in 3~6 years old children,Calculation and finishing using statistical software SPSS14.0.Results The main risk factors to S-ECC are the children life style,including feeding habits and frequency of sugar intakes,education of parents and attitudes to the oral health. Conclusion We should strengthen oral health education to the children and their parents,and the monitoring and evaluation of health education programs.Simple and effective health care project should be found to control the caries of deciduous teeth and improve the life quality in children.%  目的通过问卷调查的方式,希望能了解与S-ECC相关的行为和社会学因素,从而对今后乳牙龋病的预防治疗提供辅助依据。方法选择医院门诊和北京城市幼儿园中3~6岁儿童,进行口腔检查并对受检者的父亲或者母亲发放调查问卷。使用统计软件SPSS14.0进行计算和整理。结果无龋组和S-ECC组儿童的父母文化程度、儿童夜间饮奶习惯、常喝的饮品、睡前吃零食习惯和第一次看牙原因有显著差异。其他问卷中的因素,均无显著差异。结论应加强对儿童及家长的口腔健康教育,加强健康教育项目的监测与评估,寻找简单有效的保健项目,控制乳牙龋病,提高儿童生活质量。

  9. Un ejemplo de constitución genérica en la literatura espiritual: el «paso» del Ecce Homo

    Directory of Open Access Journals (Sweden)

    Pego Puigbó, Armando

    2001-12-01

    Full Text Available Spiritual Literature represents a very special branch within the literary system. In this article the genre of the «paso», which is completely different from the dramatic one, will be discussed beyond the traditional approches, based on thematic, formal and discoursive features. In this way, in the «paso» a possible connection of a literary kind with a kind of knowledge and experience is proposed. The Renaissance Genre-Theory can provide a view which allows us to surpass the narrow frame of mimesis. The literary kind is opened to the world, which is represented through the communicative powers of rhetoric devices. The «paso» belongs to the epidictic genre. The praise of Christ adopts the narration of a passage taken out from the Passion, according to figurae sententiae waiting for affective answers. But its spiritual condition is produced by cultural implications which warrant the correct interpretation of its meanings. Examples of Ecce homo by Francisco de Osuna, Juan de Ávila and fray Luis de Granada are analysed according to this purpose.La literatura espiritual representa una rama muy especial dentro del sistema literario. En este artículo, se discutirá el género del «paso», en nada parecido a su homónimo dramático, más allá de los criterios temático, formal y discursivo. En el «paso» puede proponerse una posible conexión entre una clase literaria y una clase de conocimiento y experiencia. La teoría renacentista de los géneros es capaz de ofrecer una perspectiva que supera el estrecho marco de la mímesis. La clase literaria se abre al mundo real, representado por medio de la fuerza comunicativa de los procedimientos retóricos. En este sentido el «paso» pertenece al género epidíctico en cuanto que la alabanza de Cristo adopta la forma de una narración extraída del relato de la Pasión. Las figuras de pensamiento buscan una respuesta afectiva, cuyo empleo y sentido son correctamente interpretados a través de

  10. 基于ECC的移动自组网成员控制方案%Member Control Scheme of Mobile Ad Hoc Networks Based on ECC

    Institute of Scientific and Technical Information of China (English)

    耿永军; 陈红军; 郑明辉

    2012-01-01

    A distributed key generation protocol is proposed by ECC based on Peterson distributed key generation scheme, which can resist malicious attack of outer or inner node. A secure member control sckeme is also proposed by using threshold digital sisgnature. By analyzing the scheme's performance and security, a conclusion is drawn that the member control policy is suitable for mobile Ad Hoc networks of limited resource devices.%基于Pederson分布式密钥产生方案,采用椭圆曲线密码体制提出一个分布式密钥产生协议,该方案高效且能抵制内外恶意节点的攻击,并采用门限数字签名方案给出一个安全的移动自组网的成员控制方案.通过方案的性能和安全性分析得出结论,该成员控制策略非常适合于资源受限的移动自组网.

  11. Experiment data report for Semiscale Mod-1 tests S-05-2A and S-05-2B (alternate ECC injection tests)

    Energy Technology Data Exchange (ETDEWEB)

    Patton, Jr., M. L.; Collins, B. L.; Sackett, K. E.

    1977-04-01

    Recorded test data are presented for Tests S-05-2A and S-05-2B of the Semiscale Mod-1 alternate ECC injection test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Tests S-05-2A and S-05-2B were conducted from initial conditions of 2263 psia and 543/sup 0/F and 2272 psia and 542/sup 0/F, respectively, to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the cold leg broken loop piping. During the tests, cooling water was injected into the intact loop pump suction and broken loop cold leg to simulate emergency core coolant injection in a PWR with flow rates based on system volume scaling. For Test S-05-2A the intact loop pump speed was held constant throughout the test at the initial blowdown value. During Test S-05-2B the pump speed was reduced and stopped according to a predetermined coastdown schedule.

  12. Ryanodine receptor type 1 (RyR1) mutations C4958S and C4961S reveal excitation-coupled calcium entry (ECCE) is independent of sarcoplasmic reticulum store depletion.

    Science.gov (United States)

    Hurne, Alanna M; O'Brien, Jennifer J; Wingrove, Douglas; Cherednichenko, Gennady; Allen, Paul D; Beam, Kurt G; Pessah, Isaac N

    2005-11-04

    Bi-directional signaling between ryanodine receptor type 1 (RyR1) and dihydropyridine receptor (DHPR) in skeletal muscle serves as a prominent example of conformational coupling. Evidence for a physiological mechanism that upon depolarization of myotubes tightly couples three calcium channels, DHPR, RyR1, and a Ca(2+) entry channel with SOCC-like properties, has recently been presented. This form of conformational coupling, termed excitation-coupled calcium entry (ECCE) is triggered by the alpha(1s)-DHPR voltage sensor and is highly dependent on RyR1 conformation. In this report, we substitute RyR1 cysteines 4958 or 4961 within the TXCFICG motif, common to all ER/SR Ca(2+) channels, with serine. When expressed in skeletal myotubes, C4958S- and C4961S-RyR1 properly target and restore L-type current via the DHPR. However, these mutants do not respond to RyR activators and do not support skeletal type EC coupling. Nonetheless, depolarization of cells expressing C4958S- or C4961S-RyR1 triggers calcium entry via ECCE that resembles that for wild-type RyR1, except for substantially slowed inactivation and deactivation kinetics. ECCE in these cells is completely independent of store depletion, displays a cation selectivity of Ca(2+)>Sr(2+) approximately Ba(2+), and is fully inhibited by SKF-96365 or 2-APB. Mutation of other non-CXXC motif cysteines within the RyR1 transmembrane assembly (C3635S, C4876S, and C4882S) did not replicate the phenotype observed with C4958S- and C4961S-RyR1. This study demonstrates the essential role of Cys(4958) and Cys(4961) within an invariant CXXC motif for stabilizing conformations of RyR1 that influence both its function as a release channel and its interaction with ECCE channels.

  13. Nietzsche como destino da filosofia e da humanidade? interpretação contextual do § 1 do capítulo "por que sou um destino", de ecce homo

    OpenAIRE

    Stegmaier,Werner

    2010-01-01

    The following translation is a reduced and revised version of the paper Schicksal Nietzsche? Zu Nietzsches Selbsteinschätzung als Schicksal der Philosophie und der Menschheit (Ecce Homo, Warum ich ein Schicksal bin §1)" - originally published in Nietzsche-Studien 37 (2008) - which was specially prepared to be presented in lecture organized by the Grupo de Pesquisa Spinoza & Nietzsche (Spinoza & Nietzsche research group - SpiN), in the Universidade Federal do Rio de Janeiro (Rio de Jan...

  14. An Improved Double-Gene Identity Authentication Protocol based on ECC%一种改进的基于ECC双因子身份认证协议

    Institute of Scientific and Technical Information of China (English)

    马丁; 马晓旭

    2013-01-01

    With the rapid development of information technology and network technology, the Internet real-name system now becomes an important trend of network supervision and management, while the user iden-tity authentication is the key to the real-name system. The identity authentication protocol based on smart-card is firstly described, and then the flaw of this protocol is discussed. With this, a double-gene identity authentication protocol based on ECC is proposed. And by using the elliptic curve discrete logarithm prob-lem and timestamp factor, the security of this protocol is ensured, the problem of smart-loss attack solved, and the high efficiency of the protocol maintained.%随着信息技术和网络技术的快速发展,互联网实名制已经成为网络监督和管理的重要趋势,而用户身份认证又是实名制管理体系中的关键技术。首先介绍了基于智能卡的身份认证协议,讨论了该协议存在的不足,并在此基础上,提出了一种基于ECC双因子的身份认证协议,通过椭圆曲线离散对数难题和时间戳因素确保协议的安全性,解决了丢失智能卡攻击的问题,并且保持了协议的高效性。

  15. 3G视频会议系统中的ECC快速算法研究%Study on ECC High-speed Algorithm in 3G Video Conference System

    Institute of Scientific and Technical Information of China (English)

    吴松洋; 武海鹰; 卢忱

    2011-01-01

    3G video conferencing system, due to its restrictions by open wireless networks, is difficult to meet the specific security requirement of the industry customers. The existing 3G video conferencing systems have many technical difficulties in encryption, one of which is high hardware requirement by conventional encryption algorithm, and large latency. ECC encryption algorithm wit a better adaptability to the requirements of 3G video terminal equipment is an applicable encryption algorithm. Based on this application, the ECC algorithm is further optimized, and thus could better adapt to the requirement of 3G video conferencing terminal. This paper proposes a fast algorithm based on ECC, which is proven to he effective in reducing resource requirement, raising operation speed, and thus up to the application requirement.%3G视频会议系统由于受到无线网络开放性的限制,难以满足行业客户的特殊安全需求。现有3G视频会议系统的加密存在着诸多技术困难,其一就是常规加密算法对硬件要求高,时延较大。ECC加密算法可以较好地适应3G视频终端设备的要求,是一种可行的加密算法。针对此应用对ECC算法做进一步的优化能更好地适应3G视频会议系统终端的需求。文章提出了一种基于ECC的快速算法,经证明可以有效降低资源需求,提高速度,达到应用要求。

  16. El Espacio de Coordinación de Centro (ECC) del Campus Virtual como plataforma para la orientación, el asesoramiento y la tutorización de estudiantes

    OpenAIRE

    Gómez Gómez, Francisco; Munuera Gómez, Pilar

    2007-01-01

    Daremos cuenta de lo planificado en el Proyecto de Innovación y Mejora de la Calidad Docente: «Tutorías, asesoramiento y orientación de los estudiantes mediante el Espacio de Coordinación de Centro (ECC) del Campus Virtual (CV) de la Universidad Complutense de Madrid (UCM)» y desarrollaremos brevemente lo realizado en tal ámbito con los 54 estudiantes matriculados en el curso académico 2005-06 en la segunda especialidad en «Orientación y consejería al niño, adolescente y psicotera...

  17. El Espacio de Coordinación de Centro (ECC) del Campus Virtual (CV) como plataforma para la orientación, el asesoramiento y la tutorización de estudiantes

    OpenAIRE

    Gómez Gómez, Francisco; Munuera Gómez, Pilar

    2007-01-01

    Daremos cuenta de lo planificado en el Proyecto de Innovación y Mejora de la Calidad Docente: “Tutorías, asesoramiento y orientación de los estudiantes mediante el Espacio de Coordinación de Centro (ECC) del Campus Virtual (CV) de la Universidad Complutense de Madrid (UCM)” y desarrollaremos brevemente lo realizado en tal ámbito con los 54 estudiantes matriculados, en el curso académico 2005-06, en la segunda especialidad en “Orientación y consejería al niño, adolescente y psicoterapia famili...

  18. Experiences with ACE inhibitors early after acute myocardial infarction. Rationale and design of the German Multicenter Study on the Effects of Captopril on Cardiopulmonary Exercise parameters post myocardial infarction (ECCE).

    Science.gov (United States)

    Kleber, F X; Reindl, I; Wenzel, M; Rodewyk, P; Beil, S; Kosloswki, B; Doering, W; Sabin, G V; Hinzmann, S; Winter, U J

    1993-12-01

    Left ventricular damage by necrosis of myocardial tissue can lead to compromise of left ventricular function, to left ventricular volume increase and ultimately to development of heart failure. This sequence in the pathophysiology has been shown to be blunted by ACE inhibitors. Volume increase, however, can also be helpful in restoring stroke volume and ameliorate elevation of filling pressures. Furthermore, very early institution of ACE inhibition has failed to improve short-term mortality after myocardial infarction in one large trial. The aim of the ECCE trial therefore is, to investigate the early effects of the ACE inhibitor captopril on compromise of exercise capacity, thought to be a first measurable sign of developing heart failure. The ECCE trial is a randomized, seven-center investigation, studying the effects of ACE inhibition on oxygen uptake in a double blind, placebo controlled design in a group of 204 patients. Sample size was calculated on the basis of a pilot trial. The study design and first not unblinded data of 104 patients are presented. The population consists of predominantly male patients with mostly first myocardial infarction. They were admitted to hospital within five hours of onset of chest pain. End-diastolic volumes were normal, but ejection fraction was moderately compromised. ACE inhibition was started after the first day, but within 72 hours of onset of chest pain. After four and after twelve weeks, oxygen uptake was considerably below expected values and one third of the patients had severe compromise of exercise capacity.(ABSTRACT TRUNCATED AT 250 WORDS)

  19. Simulation of a large break loss of coolant (LBLOCA), without actuation of the emergency injection systems (ECCS) for a BWR-5; Simulacion de un escenario de perdida de refrigerante grande (LBLOCA), sin actuacion de los sistemas de inyeccion de emergencia (ECCS) para un reactor BWR-5

    Energy Technology Data Exchange (ETDEWEB)

    Cardenas V, J.; Mugica R, C. A.; Lopez M, R., E-mail: jaime.cardenas@cnsns.gob.mx [Comision Nacional de Seguridad Nuclear y Salvaguardias, Dr. Barragan 779, Col. Narvarte, 03020 Ciudad de Mexico (Mexico)

    2015-09-15

    In this paper the analysis of scenario for the loss of coolant case was realized with break at the bottom of a recirculation loop of a BWR-5 with containment type Mark II and a thermal power of 2317 MWt considering that not have coolant injection. This in order to observe the speed of progression of the accident, the phenomenology of the scenario, the time to reach the limit pressure of containment venting and the amount of radionuclides released into the environment. This simulation was performed using the MELCOR code version 2.1. The scenario posits a break in one of the shear recirculation loops. The emergency core cooling system (ECCS) and the reactor core isolation cooling (Rcic) have not credit throughout the event, which allowed achieve greater severity on scenario. The venting of the primary containment was conducted via valve of 30 inches instead of the line of 24 inches of wet well, this in order to have a larger area of exhaust of fission products directly to the reactor building. The venting took place when the pressure in the primary containment reached the 4.5 kg/cm{sup 2} and remained open for the rest of the scenario to maximize the amount released of radionuclides to the atmosphere. The safety relief valves were considered functional they do not present mechanical failure or limit their ability to release pressure due to the large number of performances in safety mode. The results of the analysis covers about 48 hours, time at which the accident evolution was observed; behavior of level, pressure in the vessel and the fuel temperature profile was analyzed. For progression of the scenario outside the vessel, the pressure and temperature of the primary containment, level and temperature of the suppression pool, the hydrogen accumulation in the container and the radionuclides mass released into the atmosphere were analyzed. (Author)

  20. A Secure Signature Scheme for Wireless Body Area Networks Based on Network Coding and ECC Algorithm%基于网络编码和ECC的无线体域网安全签名方案

    Institute of Scientific and Technical Information of China (English)

    蒙云番; 孙光昊; 邢杰; 万海斌; 覃团发

    2015-01-01

    Security challenges in wireless body area networks ( WBAN) have been paid unprecedented at-tention for the vulnerable of patient’s personal sensitive data. In order to address prevalent security con-cerns,a secure signature scheme based on network coding and elliptic curve cryptography( ECC) algorithm is proposed. The scheme firstly introduces network coding to establish a multicast model in WBAN. The en-ergy efficiency of the network increases as more volume of data will be transmitted to the sink with the same number of transmissions. Through signing the packets by utilizing ECC algorithm,secure communication of patient-related physiological data is possible in hostile environments. The scheme includes three phases,i. e. ,setup,signature and verification. Data simulation proves that the scheme is secure,simultaneously pro-vides authentication and detects malicious nodes that intentionally corrupt content on the network.%针对无线体域网( WBAN)应用中人们关注的病患个人敏感数据在传输过程中容易受到攻击的安全问题,提出一种结合随机网络编码和椭圆曲线密码学( ECC)的安全签名方案。该方案首先在网络中引入随机网络编码建立多播网络模型,增加相同传输次数下的数据信息量;通过采用ECC算法对信息进行签名,保障病患相关生理信息的通信安全。该方案共有三个阶段,即创建、签名和验证阶段。理论证明了该方案是安全的,能够有效地对信息进行污染验证,并确定受攻击节点的位置。

  1. 小切口ECCE加loL植入在晶状体溶解性青光眼中的应用%Application of ECCE combined with loL implantation in small incision phacolytic glaucoma

    Institute of Scientific and Technical Information of China (English)

    樊奕秋; 熊世玉

    2013-01-01

    目的:浅析小切口ECCE加loL植入在晶状体溶解性青光眼中的应用。方法:按照临床治疗方式的不同,将患有晶状体溶解性青光眼的患者分为实验组和对照组,进行手术治疗。其中实验组行小切口ECCE加loL植入治疗,对照组行常规治疗,比较两组治疗疗效。结果:经过手术,实验组患有晶状体溶解性青光眼的患者角膜透明,瞳孔居中,没有出现不良反应,视力均得到不同程度提高;对照组患有晶状体溶解性青光眼的患者中有6例患者的手术失败,并出现了不良反应,其中2例最终摘除眼球。结论:在手术中,小切口ECCE加loL植入的技术,对患有晶状体溶解性青光眼的患者具有明显效果,适用于治疗晶状体溶解性青光眼的手术中。%Objective :the application of ECCE and loL implantation in small incision in the purpose of phacolytic glaucoma .Methods :according to clinical treatment in different ways ,will suffer fromphacolytic glaucoma were divided into experimental group and control group ,treatment of opera-tion .The experimental groupunderwent small incision ECCE plus loL implantation in the treatment ,the control group received routine therapy ,thera-peutic efficacy was compared between the two groups .Results:after the operation ,the experimental group withphacolytic glaucoma patients cornea was transparent ,the pupilcenter ,no adverse reaction ,visual acuity was improved to different extent ;the control group with phacolytic glaucomapa-tients failed in operation in 6 patients ,and the emergence ofadverse reactions ,including 2 cases of final enucleation of eyeball .Conclusion:in opera-tion ,small incision ECCE plus loLembedded technology ,has obvious effect on the patients withphacolytic glaucoma patients ,suitable for the treat-ment ofphacolytic glaucoma operation .

  2. Ozone profiles obtained by DIAL technique at Maïdo Observatory in La Reunion Island: comparisons with ECC ozone-sondes, ground-based FTIR spectrometer and microwave radiometer measurements

    Directory of Open Access Journals (Sweden)

    Portafaix T.

    2016-01-01

    Full Text Available A DIAL lidar system performing stratospheric ozone profile measurements from 15 to 45 km is installed at Reunion Island (southwest of Indian Ocean. The purpose of this communication is to present this DIAL system mounted now at the new Maïdo Observatory since February 2013, and the ozone profile retrieval. The first stratospheric ozone profiles obtained during 2013 and 2014 will be presented and discussed. Inter-comparison and differences observed with other high vertical resolution ozone profiles performed by ECC ozonesonde will be shown. Finally, comparisons with low vertical resolution ozone profiles retrieved from microwave and FTIR remote sensing measurements performed at Maïdo will be carried out, making appropriate use of the associated averaging kernels

  3. Ozone profiles obtained by DIAL technique at Maïdo Observatory in La Reunion Island: comparisons with ECC ozone-sondes, ground-based FTIR spectrometer and microwave radiometer measurements

    Science.gov (United States)

    Portafaix, T.; Godin-Beekmann, S.; Payen, G.; de Mazière, M.; Langerock, B.; Fernandez, S.; Posny, F.; Cammas, J. P.; Metzger, J. M.; Bencherif, H.; Vigouroux, C.; Marquestaut, N.

    2016-06-01

    A DIAL lidar system performing stratospheric ozone profile measurements from 15 to 45 km is installed at Reunion Island (southwest of Indian Ocean). The purpose of this communication is to present this DIAL system mounted now at the new Maïdo Observatory since February 2013, and the ozone profile retrieval. The first stratospheric ozone profiles obtained during 2013 and 2014 will be presented and discussed. Inter-comparison and differences observed with other high vertical resolution ozone profiles performed by ECC ozonesonde will be shown. Finally, comparisons with low vertical resolution ozone profiles retrieved from microwave and FTIR remote sensing measurements performed at Maïdo will be carried out, making appropriate use of the associated averaging kernels

  4. 老年重症瓣膜病手术的体外循环管理经验%ECC Management Experience in Aged Patients With Severe Valvular Disease

    Institute of Scientific and Technical Information of China (English)

    黄东娇; 李传在

    2015-01-01

    Objective To analyze experience of the elderly with severe valvular disease bypass ECC Management.MethodsFrom January 2011 to May 2015, a total of 132 cases over the age of 60,underwent open heart surgery. ECC methods were analyzed and summarized.Results Al 132 patients were operated successfuly,and there was no operative death. Two cases of early postoperative death due to multiple organ failure.Conclusion The way of open heart surgery in elderly patients treated with severe valvular can obtain a more significant effect.%目的:分析老年重症瓣膜病手术的体外循环经验。方法从2011年1月~2015年5月,共治疗132例60岁以上的老年瓣膜病患者,均进行心内直视手术治疗,对体外循环管理(ECC)方法进行分析总结。结果本组132例患者手术均获得成功,无手术死亡,术后早期死亡2例,原因为多脏器功能衰竭。结论采用心内直视手术方式对老年重症瓣膜病患者进行治疗,加强对体外循环管理的重视可取得理想的效果。

  5. hexA of Erwinia carotovora ssp. carotovora strain Ecc71 negatively regulates production of RpoS and rsmB RNA, a global regulator of extracellular proteins, plant virulence and the quorum-sensing signal, N-(3-oxohexanoyl)-L-homoserine lactone.

    Science.gov (United States)

    Mukherjee, A; Cui, Y; Ma, W; Liu, Y; Chatterjee, A K

    2000-04-01

    The soft-rotting bacterium, Erwinia carotovora ssp. carotovora (E. c. carotovora), produces an array of extracellular enzymes (= exoenzymes), including pectate lyase (Pel), polygalacturonase (Peh), cellulase (Cel) and protease (Prt), as well as HarpinEcc, the elicitor of hypersensitive reaction (HR). The production of these exoenzymes and HarpinEcc responds to plant products and the quorum-sensing signal [N-(3-oxohexanoyl)-L-homoserine lactone; OHL] and is subject to both transcriptional and post-transcriptional regulation. hexA of E. c. carotovora strain Ecc71 (hereafter hexA71), like that of another E. c. carotovora strain, negatively controls the production of exoenzymes, OHL and virulence in E. c. carotovora strain Ecc71. In addition to exoenzymes, HexA71 negatively regulates the expression of hrpNEcc, the structural gene for HarpinEcc. Exoenzyme overproduction is abolished by OHL deficiency in a HexA- and Ohll- double mutant, indicating that HexA and OHL are components of a common regulatory pathway controlling exoenzyme production. HexA71 negatively affects RpoS, as the levels of this alternative sigma factor are higher in the HexA- mutant than in the HexA+ strain. However, a HexA- and RpoS double mutant produces higher levels of exoenzymes and transcripts of pel-1, peh-1 and celVgenes than the HexA- and RpoS+ parent. Thus, the elevated levels of RpoS protein in the HexA- mutant do not account for exoenzyme overproduction. The following evidence associates for the first time the phenotypic changes in the HexA mutant to overproduction of rsmB RNA, a global regulator of exoenzymes, HarpinEcc, OHL and secondary metabolites. Analyses of rsmB transcripts and expression of an rsmB-lacZoperon fusion in E. c. carotovora strain Ecc71 revealed that HexA71 negatively regulates transcription of rsmB. Multiple copies of hexA71+ DNA suppress various phenotypes, including exoenzyme production in E. c. carotovora strain Ecc71, and concomitantly inhibit the production of rsm

  6. Esclavitud, libertad y devoción religiosa en Popayán. El santo Ecce Homo y el mundo de la vida de Juan Antonio de Velasco, 1650-1700

    Directory of Open Access Journals (Sweden)

    Orián Jiménez Meneses

    2015-06-01

    Full Text Available This article analyzes the genesis and consolidation of devotion to the holy Ecce Homo in the city of Popayán —located in the New Kingdom of Granada— during the second half of the 17th century. It explores the influence of this mystical experience in crystalizing the city’s religious feasts and the cultural nuances that permeated this particular invocation. It also describes the relationship of interdependence between the liberty of the free black man Juan Antonio de Velasco and other merchants, slaves, artisans, and the devout public in stabilizing this particular form of worship of the holy one. At the same time that it specifically traces the “life world” of the founder and confrere of the tradition, it calls attention to the imprint he made on this religious ritual in Popayán, “the white city.” In addition to these social factors, it also shows the influence that the generalized natural crisis of the 17th century had on the emergence of new brotherhoods, rogation days and forms of devotion.

  7. Developing the Assessment Table for Peer Review in E-C/C-E Translation%英汉互译同伴互评反馈模式测量评价表的编制开发

    Institute of Scientific and Technical Information of China (English)

    赵海娟

    2016-01-01

    Peer review , a student-oriented new teaching mode , has been widely used in English writing course , but the study of it in translation teaching has just started .The assessment table for E-C/C-E transla-tion was developed to provide a scientific and easily handled assessment tool for the English majors to con -duct peer review in translation tasks .Based on the assessment test , serial empirical researches were made to explore the implementation of peer review in the English translation teaching activities .It was found that the reliability and validity of the English translation assessment table were fairly acceptable which met the re -quirements for test compiling in psychological measurement;the assessment table exhibited better consisten-cy, stability, convergent and discriminant validity , which was of better value for popularization .%作为一种突出学生主体地位的教学新模式,同伴互评在英语写作教学中得到广泛应用,但在翻译教学中相关研究却刚刚起步。编制开发英汉互译同伴互评反馈模式测量评价表,并依据量表进行教学实验,以此促进同伴互评教学模式在英语专业翻译教学中的应用,给学习者提供科学规范、简便易施的测量工具。

  8. 结合ECC的随机序列指纹编码方案及应用%Scheme and Application on Digital Fingerprinting Based on Random Sequence and ECC

    Institute of Scientific and Technical Information of China (English)

    黄馨; 吕宏伟

    2011-01-01

    Because of development of office automation, the importance of secret document protection is becoming urgent. The disadvantages of traditional protecting techniques based on cryptography emerged. They can not protect documents after decryption or avoid misdeed of staff. Digital fingerprinting becomes a supplement. User fingerprints are embedded in order to strengthen information controllable. When illegal copy appeared, the distributor can track offenders so that document protection more effective. Here ECC is used in fingerprint code, the conventional code is used in the under layer. Then use convolution encoder to deal with the fingerprint sequences and get the output as the final fingerprint for users. In this way, the fingerprints are more robust and mistake rate is reduced.%由于办公自动化和网络化的不断发展,在政府和企业内网中对涉密电子文档保护的重要性日益凸显.传统基于密码学的保护手段的缺陷也逐步显露,不能在解密后对文档进行保护,以及对内部犯罪问题的物理防范.将数字指纹作为文档保护的补充技术,增强信息可控性,在出现非法拷贝时能追踪违规者,使文档保护更加有效.将纠错码ECC运用到指纹编码中,编码下层使用传统编码方式,再对生成的指纹序列进行卷积编码,得到最终的用户指纹序列.用户指纹具有更好的鲁棒性,能减小误判率.

  9. Extrusion of ECC: Recent Developments and Applications

    DEFF Research Database (Denmark)

    Stang, Henrik; Fredslund-Hansen, Helge; Puclin, Tony;

    2008-01-01

    process. Extrusion of cementitious (fiber reinforced) materials has proven particularly difficult due to the high inter-particle friction combined with the disastrous effect of static zones in the flow pattern, and to the ease of phase migration or separation. In order to deal with these conflicting...... demands on the rheological properties of cementitious particulate materials, various methods have been suggested to dewater the particle suspension during extrusion, however practical extrusion of thin-walled cementitious large-scale elements has not been possible until the discovery of the “dewatering...

  10. Completing the Complete ECC Formulae with Countermeasures

    Directory of Open Access Journals (Sweden)

    Łukasz Chmielewski

    2017-02-01

    Full Text Available This work implements and evaluates the recent complete addition formulae for the prime order elliptic curves of Renes, Costello and Batina on an FPGA platform. We implement three different versions:(1 an unprotected architecture; (2 an architecture protected through coordinate randomization; and (3 an architecture with both coordinate randomization and scalar splitting in place. The evaluation is done through timing analysis and test vector leakage assessment (TVLA. The results show that applying an increasing level of countermeasures leads to an increasing resistance against side-channel attacks. This is the first work looking into side-channel security issues of hardware implementations of the complete formulae.

  11. Attacks and countermeasures on AES and ECC

    DEFF Research Database (Denmark)

    Tange, Henrik; Andersen, Birger

    2013-01-01

    AES (Advanced Encryption Standard) is widely used in LTE and Wi-Fi communication systems. AES has recently been exposed to new attacks which have questioned the overall security of AES. The newest attack is a so called biclique attack, which is using the fact that the content of the state array...

  12. Effect of Sucrose Concentration on Cariogenicity of Streptococcus mutans in Dental Plaque of S-ECC%蔗糖浓度对重症婴幼儿龋菌斑中变型链球菌致龋性的影响

    Institute of Scientific and Technical Information of China (English)

    赵玮; 李文卿; 卢佳璇; 余东升

    2011-01-01

    [Objective] To determine the effect of sucrose concentration on cariogenicity of Streptococcus mutans in dental plaque of S-ECC. [Methods] Plaque samples were collected from 67 children aged from 3 to 5. Strains of Streptococcus mutans were identified, purified and then cultured in PYC medium with 1%, 5%, 10%, and 20% sucrose. The pH value of supernatant was measured to evaluate acidogencity of Streptococcus mutans, and OD600 to evaluate the propagating status. The quantities of water insoluble glucans (WIG) were measured by anthrone method. Turbidimetry was used to measure the adhesive ability. [Results] Acidogenicity, propagation, WIG synthesis, and adhesion ratio of Streptococcus mutans from S-ECC group were statistically higher than caries free group. The cariogenicity of Streptococcus mutans enhanced with the increase of sucrose concentration. In 5% sucrose group, pH decreased to critical pH5.5. Propagation, WIG synthesis and adhesion ratio increased a lot, especially in S-ECC group. When sucrose concentration was above 5%, ApH, OD600, WIG and adhesion ratio still increased, however, the growth rate became slow down. [Conclusion] The cariogenicity of Streptococcus mutans was dose-dependent with sucrose levels, and the concentration of which exceeded 5% is considered to be more cariogenic and important for S-ECC prevention.%摘要:[目的]探讨不同蔗糖浓度对重症婴幼儿龋(S-ECC)菌斑中变形链球菌致龋性的影响.[方法]采集67名3~5岁S-ECC及无龋儿童牙面菌斑,获取纯化的变链菌株,接种至蔗糖浓度分别为1%、5%、10%及20%的PYG液体培养基,采用精密pH计测变链菌产酸能力;分光光度仪测定OD600值,评价其生长情况;蒽酮法测定水不溶性葡聚糖(WIG)的量;比浊法测定变链菌的黏附比值,对比分析变形链球菌不同临床菌株的致龋性.[结果]随蔗糖浓度升高,S-ECC及无龋组变形链球菌临床分离菌株产酸、合成胞外多糖及粘附能力均

  13. 10 CFR Appendix K to Part 50 - ECCS Evaluation Models

    Science.gov (United States)

    2010-01-01

    ... non-fuel internal hardware shall be taken into account. 7. Pressurized Water Reactor Primary-to... the thermodynamic history in these regions during blowdown. 2. Frictional Pressure Drops. The... acceptable for use in predicting the critical heat flux (CHF) during LOCA transients. The computer programs...

  14. Condition For Strain-Hardening In Ecc Uniaxial Test Specimen

    DEFF Research Database (Denmark)

    Dick-Nielsen, Lars; Stang, Henrik; Poulsen, Peter Noe

    2006-01-01

    and infinite sheets under uniaxial tension. The crack is assumed to be cohesive and the cohesive law applied takes into account fiber as well as mortar properties. It is shown that the maximum crack opening observed during crack propagation in various test specimen geometries is small, 20 m and also small...... compared to typical deformations at peak bridging stress. The requirement of a minimum complementary energy for the fiber bridging curve is found not to be relevant in the aim of controlling the crack opening during crack propagation....

  15. An Efficient Method against Side-Channel Attacks on ECC

    Institute of Scientific and Technical Information of China (English)

    LIU Shuanggen; HU Yupu; XU Wensheng

    2006-01-01

    Side-channel attacks(SCA) may exploit leakage information to break cryptosystems. In this paper we present a new SCA resistant Elliptic Curve scalar multiplication algorithm. The proposed algorithm, builds a sequence of bit-strings representing the scalar k, characterized by the fact that all bit-strings are different from zero; this property will ensure a uniform computation behavior for the algorithm, and thus will make it secure against simple power analysis attacks(SPA). With other randomization techniques, the proposed countermeasures do not penalize the computation time. The proposed scheme is more efficient than M(O)ller' one, its cost being about 5% to 10% smaller than M(O)ller' one.

  16. Ecce Homo: Science and Society Need Anthropological Collections.

    Science.gov (United States)

    Sholts, Sabrina B; Bell, Joshua A; Rick, Torben C

    2016-08-01

    Scientific collections are crucial to understanding the biological and cultural diversity of the Earth. Anthropological collections document the human experience and the interactions between people, ecosystems, and organisms. Unfortunately, anthropological collections are often poorly known by the public and face a variety of threats to their permanent care and conservation.

  17. «Ecce Homo» - иконография образа страдающего Христа в западноевропейской живописи XV-XVII веков

    OpenAIRE

    БУЛГАКОВА Алина

    2016-01-01

    Статья посвящена анализу библейского сюжета «Се человек» (лат. «Ecce Homo») на примере двух картин из Большого собрания изящных искусств ASG. У одной из работ, ранее атрибутированной фламандской школой XVII века, в результате исследования и обнаружения аналогов удалось уточнить авторство и отнести ее кругу живописца Михиля Кокси II (после 1569 – 1616)....

  18. Adaptable Security in Wireless Sensor Networks by Using Reconfigurable ECC Hardware Coprocessors

    OpenAIRE

    J. Portilla; Otero, A.; de la Torre, E.; Riesgo, T.; Stecklina, O.; Peter, S; P. Langendörfer

    2010-01-01

    Specific features of Wireless Sensor Networks (WSNs) like the open accessibility to nodes, or the easy observability of radio communications, lead to severe security challenges. The application of traditional security schemes on sensor nodes is limited due to the restricted computation capability, low-power availability, and the inherent low data rate. In order to avoid dependencies on a compromised level of security, a WSN node with a microcontroller and a Field Programmable Gate Array (FPGA...

  19. ECC Based Authentication System for Performance Improvement in Security of Cloud

    Directory of Open Access Journals (Sweden)

    Sumita Dey

    2016-03-01

    Full Text Available Recent years have witnessed the trend of Craning cloud-based services for very large scale distribution, content storage and processing. Security and privacy are among top concerns for the public cloud environments. Here new methodology was clopped for assessing the cryptographic key strength. This methodology needs calculation of true economics cost of key retrieval for the most common cryptographic primitives. Valuable insight provided by resulting points over the time in the selection of cryptographic key sizes. Analysis and recommendation of parameter is an very important task for cryptographers, crucially including key size and thus implying key strength, for cryptographic primitives. Then resulting data extrapolated for the Moore’s Law and underlying algorithms by using complexity estimate, more than Moore, Less than Moore in an attempt to assess the longevity of associated keys. In this results in key size recommendations for public-key cryptosystems that over security comparable to popular symmetric cryptosystems; it leads to security estimates in terms of hardware cost or execution time.

  20. The birth of the European Crystallographic Committee (ECC) and of the European Crystallographic Meetings (ECMs)

    Science.gov (United States)

    Authier, A.

    2010-01-01

    This article describes the circumstances of the establishment of the European Crystallographic Committee, now the European Crystallographic Association, a regional associate of the IUCr, and of the European Crystallographic Meetings.

  1. ECC Based Threshold Decryption Scheme and Its Application in Web Security

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xian-feng; ZHANG Feng; QIN Zhi-guang; LIU Jin-de

    2004-01-01

    The threshold cryptography provides a new approach to building intrusion tolerance applications. In this paper, a threshold decryption scheme based elliptic curve cryptography is presented. A zero-knowledge test approach based on elliptic curve cryptography is designed. The application of these techniques in Web security is studied. Performance analysis shows that our scheme is characterized by excellent security as well as high efficiency.

  2. Fault Tolerant Approach for Data Encryption and Digital Signature Based on ECC System

    Institute of Scientific and Technical Information of China (English)

    ZENG Yong; MA Jian-feng

    2005-01-01

    An integrated fault tolerant approach for data encryption and digital signature based on elliptic curve cryptography is proposed. This approach allows the receiver to verify the sender's identity and can simultaneously deal with error detection and data correction. Up to three errors in our approach can be detected and corrected. This approach has at least the same security as that based on RSA system, but smaller keys to achieve the same level of security. Our approach is more efficient than the known ones and more suited for limited environments like personal digital assistants (PDAs), mobile phones and smart cards without RSA co- processors.

  3. Speleological study of the cavern of the Ecce homo hill, in the municipality of Chimichagua, Cesar

    Directory of Open Access Journals (Sweden)

    Frank David Lascarro-Navarro

    2015-06-01

    Full Text Available In the municipality of Chimichagua, Cesar, there is a system of natural caves associated with carbonate sedimentary rocks, which have suffered chemical dissolution and mechanical erosion generating exokarstic and endokarstic processes, which explain the geochemical and morphological phenomena that have given rise to these cavities. This study presents the results of a speleological work performed to the cavern of the Eccehomo Hill, located in the municipality of Chimichagua department of Cesar, concluding that the lithostratigraphic units outside and inside of the cavities are micritic and micritic limestones with fossils that according to the classification of Folk (1974, belong to the Formation Aguas Blancas, of the Cogollo Group. The cavities possess throughout their extension, variety of speleothems, endokarstic process products such as stalactites, moonmilk, castings, flags, sawtooth, found in the walls and ceiling.

  4. Optimized ECC Implementation for Secure Communication between Heterogeneous IoT Devices.

    Science.gov (United States)

    Marin, Leandro; Pawlowski, Marcin Piotr; Jara, Antonio

    2015-08-28

    The Internet of Things is integrating information systems, places, users and billions of constrained devices into one global network. This network requires secure and private means of communications. The building blocks of the Internet of Things are devices manufactured by various producers and are designed to fulfil different needs. There would be no common hardware platform that could be applied in every scenario. In such a heterogeneous environment, there is a strong need for the optimization of interoperable security. We present optimized elliptic curve Cryptography algorithms that address the security issues in the heterogeneous IoT networks. We have combined cryptographic algorithms for the NXP/Jennic 5148- and MSP430-based IoT devices and used them to created novel key negotiation protocol.

  5. Edaravone - citicoline comparative study in acute ischemic stroke (ECCS-AIS).

    Science.gov (United States)

    Mitta, Manish; Goel, Deepak; Bansal, Krishan K; Puri, Prashant

    2012-11-01

    Two new neuro-protective agents, Edaravone and Citicoline were recently found to be beneficial in acute ischemic stroke (AIS). But there is no study to compare these two agents on same protocol in AIS. This study was aimed to compare these two neuroprotective agents in AIS. All patients of age more than 18 years who presented within 24 hours of acute ischemic stroke were randomly treated with Edaravone (group E), Citicoline (group C) or none (group N) with other standard treatment of AIS. Modified Rankin Scale (MRS) and National Institute of Health Stroke Scale (NIHSS) were recorded on admission and at 3 months. Analysis was done using Anova t test to find out significant difference in outcome at 3 months. P value of < or = 0.05 was labeled as significant. Mean MRS and NIHSS scores at 3 months were lowest in group E (p = 0.000), suggestive of better outcome in this group. After application of severity scale, 15 patients (68.1%) in group-E, 14 (58.3%) in group C and 18 (72%) in group N had moderate to severe stroke (NIHSS of more than 10). When the patients of moderate to severe stroke were analyzed separately at 3 months, patients in group E (mean 4.46 +/- 3.52) had significantly (p = 0.00) better outcome in comparison to group C (mean 10.28 +/- 7.93) and group N (mean 9.38 +/- 6.44). Edaravone was found to be associated with better neurological outcome at 3 months. Citicoline's role as a neuroprotective agent however remains controversial in acute ischaemic stroke.

  6. Equally increased hypercoagulability irrespective of using minimized or conventional ECC systems

    DEFF Research Database (Denmark)

    Steinbrüchel, Ann S; Johansson, Pär I; Rafiq, Sulman;

    2012-01-01

    Minimized extracorporeal circulation systems in coronary artery bypass may have less impairing effect on hematological parameters and bleeding compared to conventional systems. The aim of this study was to investigate whether the use of mini systems does result in an increased postoperative hyper...

  7. Optimized ECC Implementation for Secure Communication between Heterogeneous IoT Devices

    Directory of Open Access Journals (Sweden)

    Leandro Marin

    2015-08-01

    Full Text Available The Internet of Things is integrating information systems, places, users and billions of constrained devices into one global network. This network requires secure and private means of communications. The building blocks of the Internet of Things are devices manufactured by various producers and are designed to fulfil different needs. There would be no common hardware platform that could be applied in every scenario. In such a heterogeneous environment, there is a strong need for the optimization of interoperable security. We present optimized elliptic curve Cryptography algorithms that address the security issues in the heterogeneous IoT networks. We have combined cryptographic algorithms for the NXP/Jennic 5148- and MSP430-based IoT devices and used them to created novel key negotiation protocol.

  8. On the security of pairing-free certificateless digital signature schemes using ECC

    Directory of Open Access Journals (Sweden)

    Namita Tiwari

    2015-09-01

    Full Text Available I cryptanalyze the pairing-free digital signature scheme of Islam et al. which is proven secure against “adaptive chosen message attacks”. I introduce this type of forgery to analyze their scheme. Furthermore, I comment on general security issues that should be considered when making improvements on their scheme. My security analysis is also applicable to other digital signatures designed in a similar manner.

  9. Surface and Microstructural Failures of PET-Coated ECCS Plates by Salmon-Polymer Interaction

    Directory of Open Access Journals (Sweden)

    Ernesto Zumelzu

    2016-03-01

    Full Text Available The new types of knowledge-intensive, multilayer containers consist of steel plates protected against corrosion by nanometric electrolytic chromium (Cr0 and chromium oxide (Cr2O3 layers chemically bonded to polyethylene terephthalate (PET polymer coating to preserve food. It was observed that after emptying the cans, the salmon adhered to the polymer coating, changing its color, and that this adhesion increased with longer storage times. This work was aimed at determining the product-container interactions and their characterization by X-ray diffraction (XRD, confocal Raman and micro-Raman imaging and scanning electron microscopy (SEM analysis. The zones of adhesion showed surface changes, variations in crystallinity and microstructural degradation of the PET coating. In addition, localized damages altering the functional properties of the multilayer system were observed as microcracking in the chromium layers that protect the steel. The degradation undergone was evaluated and characterized at a surface and microstructural level to establish the failure mechanisms, which were mainly associated with the activity of the adhered muscle and its biochemical components. Finally, a recommendation is done to preserve the useful life and functionality of cans for the preservation and efficient use of resources with an impact on recycling and environmental conservancy.

  10. CORNEAL ASTIGMATISM AFTER ECCE: A COMPARATIVE STUDY BETWEEN SILK VERSUS NYLON SUTURE

    Directory of Open Access Journals (Sweden)

    Sunita

    2013-11-01

    Full Text Available ABSTRAC T: INTRODUCTION: Cataract as a potent cause of loss of vision in old age persons is probably known since the dawn of human civilization. Post operative astigmatism after cataract extraction remains a big problem for cataract surgeons since Jacques Daviel e ra. Astigmatism is that type of refractive anomaly in which no point focus is formed owing to the unequal refraction of the incident light by the diopteric system of the eye in different meridians. The goal of modern cataract surgery is to produce a pseudo phakic with the quality of vision of a normal phakic eye. Various studies to find out any effect of IOL on post operative astigmatism were carried out but results are controversial. MATERIAL AND METHODS: 60 patients suffering from cataract and fit for extr action were enlisted during the month of August 2008 to February 2009. The general, physical and local examination including preoperative Keratometry, vision and tension were recorded. RESULTS: In the present study, male patients were 38 (63% and female p atients were 22 (37%. Out of the total 60 cases studied, corneo - scleral section of 28 cases (47% were sutured with 10 - 0 nylon suture (Group A while sections of 32 cases were sutured with 8 - 0 black virgin silk suture (Group B.Out of 28 cases of Group A, interrupted sutures were applied in 14 cases (50% (Group A 1 . Cross interrupted sutures were applied in 9 cases (32% Group A 2 , while bootlace continuous sutures were applied in 5 cases (18% (Group A 3 . Out of 32 cases of Group B, interrupted sutures we re applied in 26 cases (80% (Group B 1 , cross interrupted were applied in 3 cases (10% (Group B 2 , while bootlace continuous suture were applied in 3 cases (Group B 3 . In the present series, 19 cases (31% showed with the rule astigmatism, 21 cases (36% showed astigmatism against the rule and 20 cases (33% showed no astigmatism preoperatively, 16 cases were in the range of 0.50D to 1.0D and 12 cases were in the range of 1.0D to 1.50D. CONCLUSION: To conclude the findings, 10 - 0 nylon cross interrupted su tures and 8 - 0 silk cross interrupted sutures are relatively better and causes less degree of postoperative astigmatism in comparison to other suture technique. Decreased postoperative astigmatism can be achieved by posterior limbal incision, small section, limited use of sclera cauterization, proper depth of suture bite and limited use of topical steroids. Type of suture material and suture technique plays a minor role on postoperative astigmatism

  11. Keratometric astigmatism after ECCE in eastern Nepal. Continuous versus interrupted sutures.

    Directory of Open Access Journals (Sweden)

    Sood Archana

    2003-01-01

    Full Text Available Purpose: The study aimed to compute and compare the keratometric astigmatism induced by wound closure with continuous and interrupted sutures in conventional extracapsular cataract extraction with intraocular lens implantation at a single centre in eastern Nepal. Methods: Sixty eyes of 60 patients were included in the study. All patients received conventional extracapsular cataract extraction and single piece modified C-loop posterior chamber intraocular lens. Thirty eyes were sutured with continuous (Group 1 and 30 eyes with interrupted sutures (Group 2. The results were analysed by the unpaired student′s t-test. Results: At the end of 6 weeks, Group 1 patients had significantly higher astigmatism (3.53 ± 2.19D compared to Group 2 patients (1.7 ± 1.35. A majority of patients in both groups had with-the-rule astigmatism throughout the postoperative period. Conclusion: Interrupted sutures cause less astigmatism than continuous suture. The factors responsible for high astigmatism in continuous sutures call for further analysis.

  12. Keratometric astigmatism after ECCE in eastern Nepal. Continuous versus interrupted sutures.

    Science.gov (United States)

    Sood, Archana; Thakur, Sanjay Kumar D; Kumar, Sandeep; Badhu, Badri

    2003-03-01

    The study aimed to compute and compare the keratometric astigmatism induced by wound closure with continuous and interrupted sutures in conventional extracapsular cataract extraction with intraocular lens implantation at a single centre in eastern Nepal. Sixty eyes of 60 patients were included in the study. All patients received conventional extracapsular cataract extraction and single piece modified C-loop posterior chamber intraocular lens. Thirty eyes were sutured with continuous (Group 1) and 30 eyes with interrupted sutures (Group 2). The results were analysed by the unpaired student's t-test. At the end of 6 weeks, Group 1 patients had significantly higher astigmatism (3.53 +/- 2.19D) compared to Group 2 patients (1.7 +/- 1.35). A majority of patients in both groups had with-the-rule astigmatism throughout the postoperative period. Interrupted sutures cause less astigmatism than continuous suture. The factors responsible for high astigmatism in continuous sutures call for further analysis.

  13. University and place branding: The case of universities located in ECC (European Capital of Culture) cities

    OpenAIRE

    Gábor Rekettye; Gyöngyi Pozsgai

    2015-01-01

    In the globalising landscape of higher education more and more universities are going international. These universities are facing growing competition, especially in enrolling international students. International competition forces them to use marketing and especially branding activity. University branding requires that the higher education institutions clearly define their differentiating features. One of the most important differentiating features is the place where the institution is loca...

  14. El mundo del libro: El convento de Santo Ecce-Homo

    Directory of Open Access Journals (Sweden)

    Agustín Rodríguez Garavito

    1967-06-01

    Full Text Available Fray Alberto E. Ariza, O. P., es un infatigable trabajador de la inteligencia. Pertenece a la comunidad de los dominicos, la cual ha hecho tanto bien a la educación y al cristianismo en estas tierras de América. El Padre Ariza no ceja un minuto en su noble tarea de rastrear los orígenes de su Comunidad, y, particularmente lo que ella ha hecho en un Continente eruptivo, violento, cruce de razas, en donde cada columna, templo, obra pictórica, significan el producto elaborado y paciente de almas esforzadas que han pensado largamente en lo intemporal, en todo aquello que pueda servir como eje normativo de la conciencia católica en una época singularmente difícil

  15. A neW LeAdershiP for A neW eccLesioLogy

    African Journals Online (AJOL)

    a changed leadership style. sporadic efforts have been made in various parts of the world to ... call all the shots (gardner 1990:xixiii). one of the major assertions of green leaf's theory ..... greenleaf's sociological angle on leadership as service is paralleled theo logically by .... On leadership. new york: The free Press. GInI, A.

  16. ANODR-ECC Key Management protocol with TELNET to secure Application and Network layer for Mobile Adhoc Networks

    Directory of Open Access Journals (Sweden)

    G.Padmavathi

    2012-02-01

    Full Text Available A mobile ad hoc network (MANETs is a self-organizing network that consists of mobile nodes that are connected through wireless media. A number of unique features, such as lack of infrastructural or central administrative supports, dynamic network topologies, open communication channels, and limited device capabilities and bandwidths, have made secure, reliable and efficient routing operations in MANET a challenging task. The ultimate goal of the security solutions for MANET is to provide security services, such as authentication, confidentiality, integrity, anonymity, and availability to mobile users. To achieve the goals, the security solution need for entire protocol stack. . The proposed protocol ANODRECC with Telnet provide application layer security and it ensures route anonymity and location privacy and is robust against eavesdropping attack.For route anonymity, it prevents strong adversaries from tracing a packet flow back to its source or destination; for location privacy, it ensures that adversaries cannot discover the real identities of local transmitters. The simulation is done using network simulator qualnet 5.0 for different number of mobile nodes. The proposed model has exposed improved results in terms of Average throughput, Average end to end delay, Average packet delivery ratio and Average jitter.

  17. Ecce Agnus Dei, qui tollit peccata mundi. Sobre los símbolos de Jesucristo en la Edad Media

    Directory of Open Access Journals (Sweden)

    Torres Jiménez, Raquel

    2013-06-01

    Full Text Available The article deals with the symbolic meanings of Agnus Dei in the Middle Ages, its uses, reception and evolution, from the perspective of both religious and cultural history. It makes use of the analysis of the Church Fathers’ texts, Christian medieval literature, theological discourse, biblical exegesis in the medieval context, iconography, objects from churches, as well as the analysis of liturgy and mysticism. The text gives priority to an integral view of the symbol, which, beyond moral analogies, is able to explain the whole history of salvation: Agnus Dei evokes how the salvific facts of the past become present in the Eucharist and extend triumphantly into the future.El artículo trata de los significados simbólicos del Agnus Dei en la Edad Media, sus usos, recepciones y evolución, desde la perspectiva de la historia religiosa y de la historia cultural. Se sirve del análisis de textos de los Padres de la Iglesia, literatura cristiana medieval, discursos teológicos, exégesis bíblica en el contexto medieval, iconografía, objetos de iglesias, liturgia, mística. Se privilegia la visión integral de este símbolo, que, más allá de analogías morales, tiene capacidad para explicar toda la historia de la salvación: el Agnus Dei evoca cómo los hechos salvíficos del pasado se hacen presentes en la eucaristía y se proyectan triunfalmente hacia el futuro.

  18. Rethinking the status of early childhood care and education (ECCE) in rural and urban areas of South Africa.

    Science.gov (United States)

    Goduka, I

    1997-07-01

    The purpose of this study was to document the current status of, and to determine the need for, early childhood care and education in South Africa. The study included an assessment of the training needs of child carers and other individuals interested in working with young children in urban and rural areas of the region. A total of 373 African men and women with varied occupations and educational attainment were recruited in the study. A survey methodology was employed to obtain desired information. The study showed that families and communities, who have previously responded to the needs of young children including education, health, and nutrition, could no longer meet these needs because of social and economic dynamics. Training, training centers, infrastructure, and the integration of African culture in early childhood are perceived to be compelling needs. Several recommendations for policy and programs are presented.

  19. The Ecce homo that Ceán Bermúdez bought for Jovellanos and attributed to Francisco Frutet

    Directory of Open Access Journals (Sweden)

    Daniel Crespo Delgado

    2017-06-01

    Full Text Available The discovery of a painting thought to be lost, described by Juan Agustín Ceán Bermúdez in one of his earliest writings, permits the study of the relevant years he spent in Seville during his youth (1768-1778. It also leads to considerations concerning the invention of the imaginary artist to whom he attributed the painting, the controversial Francisco Frutet.

  20. Methods to homogenize electrochemical concentration cell (ECC) ozonesonde measurements across changes in sensing solution concentration or ozonesonde manufacturer

    Science.gov (United States)

    Deshler, Terry; Stübi, Rene; Schmidlin, Francis J.; Mercer, Jennifer L.; Smit, Herman G. J.; Johnson, Bryan J.; Kivi, Rigel; Nardi, Bruno

    2017-06-01

    Ozone plays a significant role in the chemical and radiative state of the atmosphere. For this reason there are many instruments used to measure ozone from the ground, from space, and from balloons. Balloon-borne electrochemical cell ozonesondes provide some of the best measurements of the ozone profile up to the mid-stratosphere, providing high vertical resolution, high precision, and a wide geographic distribution. From the mid-1990s to the late 2000s the consistency of long-term records from balloon-borne ozonesondes has been compromised by differences in manufacturers, Science Pump (SP) and ENSCI (EN), and differences in recommended sensor solution concentrations, 1.0 % potassium iodide (KI) and the one-half dilution: 0.5 %. To investigate these differences, a number of organizations have independently undertaken comparisons of the various ozonesonde types and solution concentrations, resulting in 197 ozonesonde comparison profiles. The goal of this study is to derive transfer functions to allow measurements outside of standard recommendations, for sensor composition and ozonesonde type, to be converted to a standard measurement and thus homogenize the data to the expected accuracy of 5 % (10 %) in the stratosphere (troposphere). Subsets of these data have been analyzed previously and intermediate transfer functions derived. Here all the comparison data are analyzed to compare (1) differences in sensor solution composition for a single ozonesonde type, (2) differences in ozonesonde type for a single sensor solution composition, and (3) the World Meteorological Organization's (WMO) and manufacturers' recommendations of 1.0 % KI solution for Science Pump and 0.5 % KI for ENSCI. From the recommendations it is clear that ENSCI ozonesondes and 1.0 % KI solution result in higher amounts of ozone sensed. The results indicate that differences in solution composition and in ozonesonde type display little pressure dependence at pressures ≥ 30 hPa, and thus the transfer function can be characterized as a simple ratio of the less sensitive to the more sensitive method. This ratio is 0.96 for both solution concentration and ozonesonde type. The ratios differ at pressures < 30 hPa such that OZ0. 5%/OZ1. 0 % = 0. 90 + 0. 041 ṡ log10(p) and OZSciencePump/OZENSCI = 0. 764 + 0. 133 ṡ log10(p) for p in units of hPa. For the manufacturer-recommended solution concentrations the dispersion of the ratio (SP-1.0 / EN-0.5 %), while significant, is generally within 3 % and centered near 1.0, such that no changes are recommended. For stations which have used multiple ozonesonde types with solution concentrations different from the WMO's and manufacturer's recommendations, this work suggests that a reasonably homogeneous data set can be created if the quantitative relationships specified above are applied to the non-standard measurements. This result is illustrated here in an application to the Nairobi data set.

  1. Methods to homogenize electrochemical concentration cell (ECC ozonesonde measurements across changes in sensing solution concentration or ozonesonde manufacturer

    Directory of Open Access Journals (Sweden)

    T. Deshler

    2017-06-01

    Full Text Available Ozone plays a significant role in the chemical and radiative state of the atmosphere. For this reason there are many instruments used to measure ozone from the ground, from space, and from balloons. Balloon-borne electrochemical cell ozonesondes provide some of the best measurements of the ozone profile up to the mid-stratosphere, providing high vertical resolution, high precision, and a wide geographic distribution. From the mid-1990s to the late 2000s the consistency of long-term records from balloon-borne ozonesondes has been compromised by differences in manufacturers, Science Pump (SP and ENSCI (EN, and differences in recommended sensor solution concentrations, 1.0 % potassium iodide (KI and the one-half dilution: 0.5 %. To investigate these differences, a number of organizations have independently undertaken comparisons of the various ozonesonde types and solution concentrations, resulting in 197 ozonesonde comparison profiles. The goal of this study is to derive transfer functions to allow measurements outside of standard recommendations, for sensor composition and ozonesonde type, to be converted to a standard measurement and thus homogenize the data to the expected accuracy of 5 % (10 % in the stratosphere (troposphere. Subsets of these data have been analyzed previously and intermediate transfer functions derived. Here all the comparison data are analyzed to compare (1 differences in sensor solution composition for a single ozonesonde type, (2 differences in ozonesonde type for a single sensor solution composition, and (3 the World Meteorological Organization's (WMO and manufacturers' recommendations of 1.0 % KI solution for Science Pump and 0.5 % KI for ENSCI. From the recommendations it is clear that ENSCI ozonesondes and 1.0 % KI solution result in higher amounts of ozone sensed. The results indicate that differences in solution composition and in ozonesonde type display little pressure dependence at pressures  ≥  30 hPa, and thus the transfer function can be characterized as a simple ratio of the less sensitive to the more sensitive method. This ratio is 0.96 for both solution concentration and ozonesonde type. The ratios differ at pressures < 30 hPa such that OZ0. 5%/OZ1. 0 % =  0. 90 + 0. 041 ⋅ log10(p and OZSciencePump/OZENSCI =  0. 764 + 0. 133 ⋅ log10(p for p in units of hPa. For the manufacturer-recommended solution concentrations the dispersion of the ratio (SP-1.0 / EN-0.5 %, while significant, is generally within 3 % and centered near 1.0, such that no changes are recommended. For stations which have used multiple ozonesonde types with solution concentrations different from the WMO's and manufacturer's recommendations, this work suggests that a reasonably homogeneous data set can be created if the quantitative relationships specified above are applied to the non-standard measurements. This result is illustrated here in an application to the Nairobi data set.

  2. Loss of Coolant Accident (LOCA) / Emergency Core Coolant System (ECCS Evaluation of Risk-Informed Margins Management Strategies for a Representative Pressurized Water Reactor (PWR)

    Energy Technology Data Exchange (ETDEWEB)

    Szilard, Ronaldo Henriques [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-09-01

    A Risk Informed Safety Margin Characterization (RISMC) toolkit and methodology are proposed for investigating nuclear power plant core, fuels design and safety analysis, including postulated Loss-of-Coolant Accident (LOCA) analysis. This toolkit, under an integrated evaluation model framework, is name LOCA toolkit for the US (LOTUS). This demonstration includes coupled analysis of core design, fuel design, thermal hydraulics and systems analysis, using advanced risk analysis tools and methods to investigate a wide range of results.

  3. Proactive Secret Sharing Scheme Based on ECC%一种基于ECC的动态秘密共享方案

    Institute of Scientific and Technical Information of China (English)

    范畅; 茹鹏

    2012-01-01

    Secret keepers have to face some tasks of key generation, distribution and verification in many of secret sharing schemes with trusted center. Members have difficulty in determining if the recovered secret is valid when the dealer cheats. Furthermore, those schemes are hard to achieve real proactive property. For the purpose of solving the problems, we proposed a distributed proactive secret sharing scheme based on elliptic curve cryptosystems without the trusted center. Anyone can check sub - shares provided by any members. The proactive property can be well implemented in solving secret updating and sub - shares reusing based on secure multi - party computation simulation method. Finally, the security and efficiency were analyzed in the paper. Experiments prove that; this scheme is of higher theoretical innovation and practical engineering value in terms of safety improvement, efficiency and feasible.%许多秘密共享方案需要一个可信方参与,并完成掌管秘密及子密钥的产生、分发和验证工作,一旦可信方出现欺诈或故障,成员很难判断恢复秘密的真伪,既没有解决秘密更新和子密钥复用问题,更不具有秘密的动态更新和生命期特性.为此提出了基于椭圆曲线密码体制的秘密共享方案,具有分布式和动态特性,不需要第三可信方参与,并解决了秘密更新和子密钥复用问题;利用安全多方计算的仿真方法实现;经实验证明:动态方案在安全性方面有所提高,在效率方面可行,具有较高的理论创新和实践工程价值.

  4. The design and analysis of an ECC Signcryption Scheme%一个ECC签密方案的设计分析

    Institute of Scientific and Technical Information of China (English)

    胡越梅

    2012-01-01

    Based on the Elliptic Curve Cryptosystem, and by improving the traditional signcryption, this paper designs a new signcryption scheme. Analysis inditates this scheme can resist kinds of attacks, offer forward - security and third party verifica- tion, thus assuring the security and fairness of the system. In addition, the calculation and communication efficiency have been improved, so the scheme has its practical value.%论文基于椭圆曲线密码体制(ECC),对传统签密方案进行改进,设计了一个新的签密方案.分析显示,方案可以抵抗各种攻击,并能同时提供前向安全性和支持第三方验证,保证了系统的安全性和公正性;并提高了计算和通信效率.具备一定的实用价值.

  5. 一种基于AES、ECC和Tate配对的签名加密算法%A SIGNATURE ENCRYPTION ALGORITHM BASED ON AES,ECC AND TATE PAIRING

    Institute of Scientific and Technical Information of China (English)

    周明星; 周建江; 杨小东; 张贵仓

    2008-01-01

    结合椭圆曲线上的Tate配对和混合加密体制,提出了一种新的签名加密算法,它集密钥交换、数字签名和数据加密解密功能于一体,能完全抵抗生日攻击,既安全又实用,特别适用于电子商务系统.

  6. 留守儿童早期龋的研究现状%The ECC research status of left-behind children

    Institute of Scientific and Technical Information of China (English)

    刘君武

    2013-01-01

    The left-behind children is a vulnerable groups, which should not be neglected at present stage of our country and the problem of Physiological and psychological is very serious. Early childhood caries is a main disease which influence on children's oral health .There are many factors that affect the disease. This paper wil review and discuss previous literature to Make a summary of Early childhood caries risk factors and status about left-behind children.%  留守儿童是我国现阶段不可忽视的一个弱势群体,生理及心理问题普遍突出。儿童早期龋又是影响儿童口腔健康的重要疾病,发病因素多样。本文将以往文献进行回顾讨论,对留守儿童早期龋现状及病因做一归纳论述。

  7. 尼采伦理学与文学研究:读《瞧!这个人》%Nietzsche's Ethics and Literary Studies: A Reading of Ecce Homo

    Institute of Scientific and Technical Information of China (English)

    大卫·帕克; 牟芳芳

    2006-01-01

    20世纪七八十年代,后现代主义差异政治主导了文学研究,并把该领域对伦理学和美学价值的关注贬为过时.本文通过引用、评述尼采的自传,借鉴英美当代道德哲学家的论述,反驳了新尼采主义者杰姆逊等人把尼采伦理学看作差异政治代码的误读,指出尼采通过讲述他如何成为自己的故事,不仅对他重新评估一切价值的肯定性伦理学给出了例证,也阐明了伦理学价值与美学价值的紧密联系.

  8. The influence of magnetostatic interactions in exchange-coupled composite particles

    DEFF Research Database (Denmark)

    Vokoun, D.; Beleggia, Marco; De Graef, M.;

    2010-01-01

    Exchange-coupled composite (ECC) particles are the basic constituents of ECC magnetic recording media. We examine and compare two types of ECC particles: (i) core-shell structures, consisting of a hard-magnetic core and a coaxial soft-magnetic shell and (ii) conventional ECC particles, with a hard...

  9. Evaluation of possible associated factors for early childhood caries and severe early childhood caries: a multicenter cross-sectional survey

    NARCIS (Netherlands)

    Özen, B.; van Strijp, A.J.P.; Özer, L.; Olmus, H.; Genc, A.; Cehreli, S.B.

    2016-01-01

    Objectives: The present study evaluated associated factors for developing early childhood caries (ECC) and Severe-ECC (S-ECC) in a group of children aged 24–71 months. Potential positive effects of early dental visit on formation of ECC is investigated as well. Study Design: This was a multicenter,

  10. Evaluation of possible associated factors for early childhood caries and severe early childhood caries: a multicenter cross-sectional survey

    NARCIS (Netherlands)

    Özen, B.; van Strijp, A.J.P.; Özer, L.; Olmus, H.; Genc, A.; Cehreli, S.B.

    2016-01-01

    Objectives: The present study evaluated associated factors for developing early childhood caries (ECC) and Severe-ECC (S-ECC) in a group of children aged 24–71 months. Potential positive effects of early dental visit on formation of ECC is investigated as well. Study Design: This was a multicenter,

  11. E-commerce Rapid Design and Implementation Based on ECC%基于椭圆曲线密码体制电子商务的快速设计与实现

    Institute of Scientific and Technical Information of China (English)

    黄剑华; 马婷

    2012-01-01

    Based on the elliptic curve encryption scheme of Elgamal system needs of plaintext embedding ellipse curve and the shortcomings of the existing ECDSA the need for inverse time consuming operation,under the precondition of satisfying security is presented in this paper is not restricted to plaintext must embed elliptic curve encryption scheme of Meneses-Vanstone system and need not be inversed ECDSA solutions,to effectively improve the elliptic curve cryptography in electronic commerce electronic data encryption and digital signature speed.%本文针对椭圆曲线Elgamal体制加密方案需要明文嵌入椭圆曲线的缺点和现有的椭圆曲线数字签名(ECDSA)需要进行求逆的非常耗时运算的瓶颈,在满足安全性的前提下本文提出没有限制明文一定要嵌入椭圆曲线M—V体制的加/解密方案和不需要进行求逆运算椭圆曲线数字签名(ECDSA)方案,有效地提高了椭圆曲线密码体制应用在电子商务中的电子数据加密和数字签名的速度。

  12. El compositor Josep Pons i el llenguatge musical per a la litúrgia de l'ordinarium: "Missa a 4 ÿ a 8 con oboes, violines ÿ trompas sobre l'antífona Ecce Sacerdos Magnus" (1786)

    OpenAIRE

    Ramirez I Beneyto, Ramon

    2004-01-01

    RESUM L'autor divideix la present tesi en dos grans blocs: el primer dedicat als aspectes històrics, en els quals s'emmarca la figura del personatge estudiat i el segon atenent específicament als aspectes purament tècnics del seu llenguatge musical, mitjançant lestudi de l'obra recuperada. En la primera part es planteja una aproximació a la figura del mestre Pons a partir de la reconstrucció del seu periple vital, des que nasquera a Girona en 1.770 fins que es va produir ...

  13. Ozone profiles obtained by DIAL technique at Maïdo Observatory in La Réunion Island: comparisons with ECC ozone-sondes, ground-based FTIR spectrometer and microwave radiometer measurements

    OpenAIRE

    Portafaix T.; Godin-Beekmann S.; Payen G.; de Mazière M.; Langerock B.; Fernandez S; Posny F.; Cammas J.P.; Metzger J. M.; Bencherif H.; Vigouroux C.; Marquestaut N.

    2016-01-01

    International audience; A DIAL lidar system performing stratospheric ozone profile measurements from 15 to 45 km is installed at Reunion Island (southwest of Indian Ocean). The purpose of this communication is to present this DIAL system mounted now at the new Maïdo Observatory since February 2013, and the ozone profile retrieval. The first stratospheric ozone profiles obtained during 2013 and 2014 will be presented and discussed. Inter-comparison and differences observed with other high vert...

  14. Analysis of ROSA 1.1 test with TRACE code: ECSS water injection under natural circulation conditions; Analisis con el codigo TRACE del test ROSA 1.1: Inyeccion de agua ECCS bajo condiciones de circulacion natural

    Energy Technology Data Exchange (ETDEWEB)

    Julibe, A. J.; Munoz-Coba, J. L.; Escriva, A.; Romero, A.

    2010-07-01

    This paper is based on modelling the ROSA 1.1 test by TRACE code. The ROSA 1.1 test presents several natural flow phases in biphasic conditions and this was the cause of this work. Therefore, the aim of this paper is verify the TRACE code ability to simulate such flows using standard components and modules.

  15. Angiotensin-converting enzyme inhibitors in preventing remodeling and development of heart failure after acute myocardial infarction: results of the German multicenter study of the effects of captopril on cardiopulmonary exercise parameters (ECCE).

    Science.gov (United States)

    Kleber, F X; Sabin, G V; Winter, U J; Reindl, I; Beil, S; Wenzel, M; Fischer, M; Doering, W

    1997-08-04

    Early action of angiotensin-converting enzyme (ACE) inhibitors after myocardial infarction (MI) has been shown in large scale clinical trials to reduce mortality over the first weeks. However, the mechanisms involved are yet unclear and several trials showed a tendency toward a small, albeit unexpected, rise in cardiogenic shock or mortality. Since cardiopulmonary exercise testing (CPX) has become a "gold standard" in assessing the severity of heart failure, we studied--after finishing a pilot trial--the effect of captopril versus placebo in 208 patients who were individually titrated (titrated dose, mean 46/69 mg/day after 7 days/4 weeks, respectively) in order to preserve their blood pressure in the acute phase of myocardial infarction; we followed the development of congestive heart failure (CHF) over 4 weeks by measuring oxygen consumption. After 4 weeks, overall oxygen consumption at the anaerobic threshold (VO2-AT; 13.7 vs 13.1), maximal oxygen consumption (VO2max 19.3 vs 18.9 mL/kg per min) and exercise duration (896 vs 839 sec) showed a nonsignificant difference in favor of the captopril group. The predefined, categorized, combined endpoint of severe heart failure or death (heart failure necessitating ACE inhibition, VO2max 10 patients per 100 treated gained major benefits from this therapy.

  16. 曲げ試験によるPVA-ECCの引張性能評価

    OpenAIRE

    清水, 克将; 金久保, 利之; 閑田, 徹志; 永井, 覚

    2006-01-01

    ECC (Engineered Cementitious Composites), which is grouped in one of the fiber reinforced cementitious composites, shows pseudostiain hardening behavior with several percent tensile strain and multiple cracks. Evaluation method for tensile properties (tensile strength and ultimate strain) of ECC is proposed by using bending test results. In this research, uniaxial tension test and bending test of PVA-ECC (ECC with Polyvinyl alcohol fiber) is conducted to obtain correlation between tensile pro...

  17. Comparison of Candida species isolated from children with and without early childhood caries: A descriptive cross-sectional study

    Directory of Open Access Journals (Sweden)

    M S Beena

    2017-01-01

    Full Text Available Background: Early childhood caries (ECC is characterized by the presence of one or more decayed, missing (due to caries, or filled teeth surfaces in any primary tooth, in a child below 6 years of age. Although ECC is primarily associated with high levels of maternal Streptococcus mutans, there has been an increased interest in finding the relationship between oral fungal flora and dental caries. Objective: The aim of the study is to identify and characterize the Candida species and to compare the candidal isolates in children with ECC and without ECC. Materials and Methods: The study was conducted on children below 6 years of age, who were categorized into ECC and non-ECC groups of fifty children each. Samples were collected using sterile cotton swabs and were inoculated on Sabouraud's Dextrose Agar and incubated at 37°C for 24 h. Candidal colonies were isolated, species identified and virulence factors tested for both ECC and non-ECC groups. Results: The candidal carriage among the ECC children was found to be 84%, which was significantly higher than the non-ECC group of 24%. Candida albicans and non-albicans Candida (NAC were isolated in both ECC and non-ECC groups. Phospholipase production was significantly high in ECC group whereas hemolysin production and germ tube formation showed no significant difference between the two groups. Conclusion: A significant correlation was found between the presence of Candida and ECC. NAC also plays an important role in the development of ECC. The virulence factors such as phospholipase may be responsible for the pathogenicity of Candida in the development of ECC.

  18. The Expanded Core Curriculum: Where We Have Been, Where We Are Going, and How We Can Get There

    Science.gov (United States)

    Sapp, Wendy; Hatlen, Phil

    2010-01-01

    Although teachers consider the Expanded Core Curriculum (ECC) critical for students' success, they do not provide their students adequate instruction based on principles of the ECC. A minimum level of competence for assessment and instruction in the ECC should be established for novice teachers. Personnel preparation programs should evaluate how…

  19. Listening to the Voice of the Customer.

    Science.gov (United States)

    Schauerman, Sam; And Others

    One of the major tenets of Total Quality Management (TQM) is that organizations need to adopt a strong customer focus. At El Camino College (ECC) in Torrance, California, a matrix was developed to identify and describe ECC's direct and indirect internal and external customers. ECC then applied Quality Function Deployment (QFD), a strategic tool…

  20. Association between Streptococcus mutans and Candida albicans among 3–5-year-old children with early childhood caries: A cross-sectional study

    Directory of Open Access Journals (Sweden)

    F Farhanaz

    2017-01-01

    Full Text Available Introduction: Streptococcus mutans infection has been identified as an important microbial factor for early childhood caries (ECC. Candida species has been shown to enhance the adherence of S. mutans to the oral biofilm and carious tooth substance. However, there is a paucity of the literature regarding the association between S. mutans and Candida albicans related to the ECC. Aim: To assess and compare the levels of S. mutans and C. albicans among 3–5-year-old preschool children with and without ECC and to determine the association between them. Materials and Methods: A cross-sectional study was conducted among 30 children with ECC (ECC group and 30 children without ECC (non-ECC group. Dental caries was assessed, and unstimulated saliva samples were collected. S. mutans and C. albicans counts were determined using Mutans-Sanguis agar and CHROMagar, respectively. Chi-square test and logistic regression were used. Significance levels were set at 5%. Results: There was a significant difference between ECC group and non-ECC group for S. mutans (P = 0.04 and C. albicans (P = 0.02 levels. There was no significant association between S. mutans and C. albicans in ECC and non-ECC groups. Children with ECC were more likely to have high levels of S. mutans and C. albicans when compared to non-ECC group. Conclusion: Children with ECC presented higher levels of S. mutans and C. albicans compared to children without ECC. High affinity between S. mutans and C. albicans suggests interaction between these diverse species that may mediate cariogenic development.

  1. Metabolic aspects of acute tissue hypoxia during extracorporeal circulation and their modification induced by L-carnitine treatment.

    Science.gov (United States)

    Corbucci, G G; Menichetti, A; Cogliatti, A; Nicoli, P; Ruvolo, C

    1992-01-01

    In this study the authors examine the effects of acute hypoxia due to extracorporeal circulation (ECC) and the role played by L-carnitine treatment on some plasmatic metabolites linked to glycolytic cellular metabolism. To obtain biochemical data, 120 patients in extracorporeal circulation during aortopulmonary bypass surgery were evaluated. The patients received either sodium bicarbonate (40 patients), or L-carnitine during ECC (40 patients) or before and during ECC (40 patients), and plasma samples were collected before ECC, during ECC and after ECC. The levels of lactate and pyruvate showed significant alterations in sodium bicarbonate-treated patients, and there was also a considerable imbalance in the succinate/fumarate ratio. This means that tissue hypoxia due to ECC leads to cellular oxidative damage and to a considerable decrease in the intracellular energy pools. The use of L-carnitine antagonizes the oxidative stress, as is well documented by the levels of plasmatic metabolites which remain confined to normal amounts.

  2. Repeated blood flow restriction induces muscle fiber hypertrophy.

    Science.gov (United States)

    Sudo, Mizuki; Ando, Soichi; Kano, Yutaka

    2017-02-01

    We recently developed an animal model to investigate the effects of eccentric contraction (ECC) and blood flow restriction (BFR) on muscle tissue at the cellular level. This study clarified the effects of repeated BFR, ECC, and BFR combined with ECC (BFR+ECC) on muscle fiber hypertrophy. Male Wistar rats were assigned to 3 groups: BFR, ECC, and BFR+ECC. The contralateral leg in the BFR group served as a control (CONT). Muscle fiber cross-sectional area (CSA) of the tibialis anterior was determined after the respective treatments for 6 weeks. CSA was greater in the BFR+ECC group than in the CONT (P muscle fiber hypertrophy at the cellular level. Muscle Nerve 55: 274-276, 2017. © 2016 Wiley Periodicals, Inc.

  3. Prevalence and distribution of regional scar in dysfunctional myocardial segments in Duchenne muscular dystrophy

    Directory of Open Access Journals (Sweden)

    Crawford Thomas O

    2011-03-01

    Full Text Available Abstract Background The segmental relationship between cardiovascular magnetic resonance (CMR peak circumferential strain (Ecc and myocardial scar has not been well characterized in Duchenne muscular dystrophy (DMD, and it is unknown whether echocardiography accurately measures Ecc in DMD. We assessed segmental Ecc and scar using CMR with myocardial tissue tagging and late gadolinium enhancement (LGE in patients with DMD, then compared CMR with echocardiographic velocity vector imaging (VVI for regional Ecc based on independent observer assessments. Results Participants enrolled (n = 16; age 8-23 had median left ventricular (LV ejection fraction of 0.52 (range 0.28-0.69, and 156 basal and mid-cavity myocardial segments from the 13 patients completing the LGE protocol were analyzed for strain and scar. Segmental CMR Ecc in the most negative quartile (quartile 4 ruled out scar in that segment, but scar was present in 46% of segments in the least negative (most dysfunctional Ecc quartile 1, 33% of Ecc quartile 2 segments, and 15% of Ecc quartile 3 segments. Overall scar prevalence in inferior, inferolateral, and anterolateral segments was eight times higher than in inferoseptal, anteroseptal, and anterior segments (p Conclusions The relationship between scar and Ecc in DMD is complex. Among myocardial segments with depressed Ecc, scar prevalence was much higher in inferior, inferolateral, and anterolateral segments, indicating a regionally dependent association between abnormal Ecc and scar, with free wall segments commonly developing dysfunction with scar and septal segments developing dysfunction without scar. Although normal echocardiographic Ecc predicted absence of scar, regional echocardiographic Ecc by VVI has only a limited association with CMR Ecc in DMD.

  4. Plasma macrophage colony-stimulating factor levels during cardiopulmonary bypass with extracorporeal circulation

    Directory of Open Access Journals (Sweden)

    Y. Denizot

    1996-01-01

    Full Text Available Leukocytosis and thrombocytopenia occur during cardiopulmonary bypass (CPB with extracorporeal circulation (ECC. Elevated circulating concentrations of macrophage colony-stimulating factor (M-CSF are reported during thrombocytopenia and leukopenia of different origins. We have assessed M-CSF concentrations in 40 patients undergoing CPB with ECC. Plasma M-CSF concentrations were stable during ECC and increased at the 6th (7.3 ± 0.7 IU/μg protein and 24th (8.6 ± 0.8 IU/μg protein postoperative hour compared with pre-ECC values (4.9 ± 0.5 IU/μg protein. A deep thrombocytopenia was found during ECC and until the 24th postoperative hour. A drop of leukocyte counts was found during ECC followed by an increase after ECC weaning. While no correlation was found between M-CSF concentrations and the leukocyte counts, M-CSF values were positively correlated with platelet counts only before and during ECC. Thus, M-CSF is not implicated in the thrombocytopenia and the leukopenia generated during CPB with ECC. However the elevated levels of M-CSFa few hours after the end of ECC might play a role in the inflammatory process often observed after CPB.

  5. Conductivity-based strain monitoring and damage characterization of fiber reinforced cementitious structural components

    Science.gov (United States)

    Hou, Tsung-Chin; Lynch, Jerome P.

    2005-05-01

    In recent years, a new class of cementitious composite has been proposed for the design and construction of durable civil structures. Termed engineered cementitious composites (ECC), ECC utilizes a low volume fraction of short fibers (polymer, steel, carbon) within a cementitious matrix resulting in a composite that strain hardens when loaded in tension. By refining the mechanical properties of the fiber-cement interface, the material exhibits high tolerance to damage. This study explores the electrical properties of ECC materials to monitor their performance and health when employed in the construction of civil structures. In particular, the conductivity of ECC changes in proportion to strain indicating that the material is piezoresistive. In this paper, the piezoresistive properties of various ECC composites are thoroughly explored. To measure the electrical resistance of ECC structures in the field, a low-cost wireless active sensing unit is proposed. The wireless active sensing unit is capable of applying DC and AC voltage signals to ECC elements while simultaneously measuring their corresponding voltages away from the signal input. By locally processing the corresponding input-output electrical signals recorded by the wireless active sensing units, the magnitude of strain in ECC elements can be calculated. In addition to measuring strain, the study seeks to correlate changes in ECC electrical properties to the magnitude of crack damage witnessed in tested specimens. A large number of ECC specimens are tested in the laboratory including a large-scale ECC bridge pier laterally loaded under cyclically repeated drift reversals. The novel self-sensing properties of ECC exploited by a wireless monitoring system hold tremendous promise for the advancement of structural health monitoring of ECC structures.

  6. Designing added functions in engineered cementitious composites

    Science.gov (United States)

    Yang, En-Hua

    In this dissertation, a new and systematic material design approach is developed for ECC with added functions through material microstructures linkage to composite macroscopic behavior. The thesis research embodies theoretical development by building on previous ECC micromechanical models, and experimental investigations into three specific new versions of ECC with added functions aimed at addressing societal demands of our built infrastructure. Specifically, the theoretical study includes three important ECC modeling elements: Steady-state crack propagation analyses and simulation, predictive accuracy of the fiber bridging constitutive model, and development of the rate-dependent strain-hardening criteria. The first element establishes the steady-state cracking criterion as a fundamental requirement for multiple cracking behavior in brittle matrix composites. The second element improves the accuracy of crack-width prediction in ECC. The third element establishes the micromechanics basis for impact-resistant ECC design. Three new ECCs with added functions were developed and experimentally verified in this thesis research through the enhanced theoretical framework. A green ECC incorporating a large volume of industrial waste was demonstrated to possess reduced crack width and drying shrinkage. The self-healing ECC designed with tight crack width was demonstrated to recover transport and mechanical properties after microcrack damage when exposed to wet and dry cycles. The impact-resistant ECC was demonstrated to retain tensile ductility with increased strength under moderately high strain-rate loading. These new versions of ECC with added functions are expected to contribute greatly to enhancing the sustainability, durability, and safety of civil infrastructure built with ECC. This research establishes the effectiveness of micromechanics-based design and material ingredient tailoring for ECC with added new attributes but without losing its basic tensile ductile

  7. In vitro evaluation of the air separation ability of four cardiovascular manufacturer extracorporeal circuit designs.

    Science.gov (United States)

    Dickinson, Timothy A; Riley, Jeffrey B; Crowley, Jeffrey C; Zabetakis, Paul M

    2006-09-01

    Neurologic impairment is a common complication of adult cardiac surgery. Cerebral gaseous microemboli (GME) detected during cardiopulmonary bypass has been associated with cognitive impairment after adult cardiac surgery. Several previous studies have shown that components comprising the extracorporeal circuit (ECC) can affect the ability of the ECC to eliminate air. The differences in the air separation ability of four manufacturer's commonly used ECCs were studied. The air-separating ability of Cobe Cardiovascular, Gish Biomedical, Medtronic, and Terumo Cardiovascular Systems Corp. ECCs were studied in vitro under clinically relevant conditions. Bolus and continuous venous air were introduced and output GME patterns by size, time, and count were measured (using an embolus detection device) and statistically analyzed. Graphic representations depicting elapsed time, GME size, and bubble count helped to visually rank the air-handling performance of the ECCs. There are significant air-handling differences between the ECCs tested. Overall, the blinded results reveal that ECC A and ECC C removed significantly (p challenges, ECC B and ECC D allowed significantly more GME to pass (p high-intensity transient signals (HITS) compared with the 9600 from the ECC B during venous room air entrainment at 100 mL/min. There are substantial and significant air-handling differences between the ECCs from the four different manufacturers. The results from this work allow for objective characterization of ECCs air-separating ability. This additional information provides an opportunity for clinicians to potentially minimize the risks of arterial air embolization and its associated deleterious neurologic effects, while allowing clinicians to make better-informed consumer decisions.

  8. Spanish participation in the R and D program in radiation protection within the field''Safety in Nuclear Fission'' of ECC (1992-1993). Participacion espaola en el programa de I+D en proteccion radiologica dentro del area de '' Seguridad de la fision nuclear'' de la CEE (1992-93)

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    Twenty two Spanish research teams from Universities, Hospitals, Foundations, as well as CIEMAT, have received contributions from the EC of 188 million pesetas. This funding corresponds to the Program: ''Research in radiation protection'' for the period 1992-1993. The total budget of the program is 3400 million pesetas.

  9. Ecce sacerdos magnus” : as entradas dos bispos nas dioceses de regio patronato. Uma comparação entre o vice-reino de Nápoles e os espaços portugueses (séculos XVI-XVIII

    Directory of Open Access Journals (Sweden)

    Paola Nestola

    2014-01-01

    Full Text Available This study takes into consideration two distant and different spaces, compared through ceremonies of bishop’s entry. Based on visual and written documents, this comparative exercise is focused on solemn Episcopal entries into some dioceses of the kingdom of Naples, until now neglected by historiography, and on those of the Portuguese territory of Europe and overseas. The study tries to answer to the following questions: what are the categories that give meaning to this high moment of manifestation and representation of the Episcopal dignity, as well as the city center of the diocesan government? Chronological and spatial dimension, symbolic, theological and topographical systems can contribute to make intelligible the extraordinary community rites linked to the Tridentine reform direct in the half of XVI century? Which elements distinguish or approach the socio-cultural dynamics generated in the different territories examined?

  10. EFFECTS OF ECCENTRIC EXERCISE ON ANAEROBIC POWER, STARTING SPEED AND ANAEROBIC ENDURANCE

    OpenAIRE

    Maciejczyk, Marcin; Szymura, Jadwiga; Wiecek, Magdalena; Szygula, Zbigniew; Kepinska, Magdalena; Ochalek, Katarzyna; Pokrywka, Andrzej

    2015-01-01

    The aim of this study was to evaluate the effects of eccentric exercise on anaerobic power, starting speed and anaerobic endurance. The participants performed the maximum cycling sprint test (MCST) prior to eccentric exercise (ECC), 10 minutes after, as well as one hour, 24 hours, 48 hours, and one week after ECC. The peak and mean power, time to attain peak power, time of maintaining peak power and power decrease were measured in the MCST. Before and after ECC, the myoglobin concentration...

  11. Selective inhibition of the platelet phosphoinositide 3-kinase p110beta as promising new strategy for platelet protection during extracorporeal circulation.

    Science.gov (United States)

    Straub, Andreas; Wendel, Hans Peter; Dietz, Klaus; Schiebold, Daniela; Peter, Karlheinz; Schoenwaelder, Simone M; Ziemer, Gerhard

    2008-03-01

    Extracorporeal circulation (ECC) is used in cardiac surgery for cardiopulmonary bypass as well as in ventricular assist devices and for extracorporeal membrane oxygenation. Blood contact with the artificial surface and shear stress of ECC activates platelets and leukocytes resulting in a coagulopathy and proinflammatory events. Blockers of the platelet glycoprotein (GP) IIb/IIIa (CD41/CD61) can protect platelet function during ECC, a phenomenon called "platelet anaesthesia", but may be involved in post-ECC bleeding. We hypothesized that the new selective phosphoinositide 3-kinase p110beta inhibitor TGX-221 that inhibits shear-induced platelet activation without prolonging the bleeding time in vivo may also protect platelet function during ECC. Heparinized blood of healthy volunteers (n = 6) was treated in vitro with either the GP IIb/IIIa blocker tirofiban, TGX-221 or as control and circulated in an ECC model. Before and after 30 minutes circulation CD41 expression on the ECC-tubing as measure for platelet-ECC binding and generation of the platelet activation marker beta-thromboglobulin were determined using ELISA. Platelet aggregation and platelet-granulocyte binding were analysed in flow cytometry. After log-transforming the data statistical evaluation was performed using multifactor ANOVA in combination with Tukey's HSD test (global alpha = 5%). Tirofiban and TGX-221 inhibited platelet-ECC interaction, platelet aggregation and platelet-granulocyte binding. Tirofiban also inhibited ECC-induced beta-thromboglobulin release. The observed inhibition of platelet-ECC interaction and platelet activation by tirofiban contributes to explain the mechanism of "platelet anaesthesia". TGX-221 represents a promising alternative to GP IIb/IIIa blockade and should be further investigated for use during ECC in vivo.

  12. JPRS Report, West Europe.

    Science.gov (United States)

    2007-11-02

    European Economic Community [ECC][as printed], the establishment of an ECC domestic market , the coales- cence of an ECC technological community—all...supposed to have greeted other guests in the hall of the hostel with the words "Heil Hitler" and "Sieg Heil." The three defendants are alleged to have... hostel , accosting women and girls. In this context, justice officals speak of vandalism whereby a closet door was demolished. During these incidents

  13. Optimizing Crisis Action Planning in the Noncombatant Evacuation Operation Setting

    Science.gov (United States)

    2010-06-01

    upgrade the mass evacuation computer program (MASSVAC), which is a virtual simulation, and compare its new algorithm efficiency in a nuclear power plant...ECC-SPOE) = Average B1 DoS_16 B2 DoS_20 B: ECC Schedule Fast Mixed Slow Interaction A: ECC Process Speed Ma xA vg La stT SH Tim e 100 102 104 106 108...Interaction A: ECC Process Speed Ma xA vg La stT SH Tim e 100 102 104 106 108 110 112 114 Warning! Term involved in multiple interactions. 79

  14. Magnetic properties of soft layer/FePt-MgO exchange coupled composite Perpendicular recording media

    Institute of Scientific and Technical Information of China (English)

    Yin Jin-Hua; Takao Suzuki; Pan Li-Qing

    2008-01-01

    The magnetic properties of exchange coupled composite(ECC)media that are composed of perpendicular magnetic recording media FePt-MgO and two kinds of soft layers have been studied by using an x-ray diffractometer,a polar Kerr magneto-optical system(PMOKE)and a vibrating sample magnetometer(VSM).The results show that ECC media can reduce the coercivities of perpendicular magnetic recording media FePt-MgO.The ECC media with granular-type soft layers have weaker exchange couplings between magnetic grains and the magnetization process,for ECC media of this kind mainly follow the Stoner-Wohlfarth model.

  15. Genotypic diversity and phenotypic traits of Streptococcus mutans isolates and their relation to severity of early childhood caries.

    Science.gov (United States)

    Valdez, Remberto Marcelo Argandoña; Duque, Cristiane; Caiaffa, Karina Sampaio; Dos Santos, Vanessa Rodrigues; Loesch, Maria Luiza de Aguiar; Colombo, Natalia Helena; Arthur, Rodrigo Alex; Negrini, Thais de Cássia; Boriollo, Marcelo Fabiano Gomes; Delbem, Alberto Carlos Botazzo

    2017-07-14

    Early childhood caries (ECC) is an aggressive condition that can affect teeth of young children. This study aimed to evaluate genotypic diversity and phenotypic traits of S. mutans isolated from dental biofilms of children with different caries status in comparison with caries free (CF) children. Streptococcus mutans strains were isolated from supragingival biofilm samples of CF, ECC and severe-ECC (S-ECC) children and genotyped by arbitrary-primer polymerase chain reaction - AP-PCR. S. mutans genotypes were tested for their ability to reduce the suspension pH through glycolysis, to tolerate extreme acid challenge and by their ability to form biofilm. Response variables were analyzed by ANOVA/Tukey or Kruskal-Wallis/Mann-Whitney tests at a 5% of significance. There was an increase in the prevalence of Streptococcus mutans in biofilms with the severity of dental caries. No differences in genotypic diversity and in acidogenicity of genotypes were found among CF, ECC and S-ECC children. S mutans strains with genotypes more characteristic for ECC and S-ECC children formed more biofilms than those identified in CF children. The strains isolated from S-ECC children were highly acid tolerant. Although S. mutans genotypic diversity was similar among the groups of children, phenotypic traits of S. mutans, especially the acid tolerance response, could explain the severity of early childhood caries.

  16. Comparison of Oxygen Consumption in Rats During Uphill (Concentric and Downhill (Eccentric Treadmill Exercise Tests

    Directory of Open Access Journals (Sweden)

    Vivien Chavanelle, Pascal Sirvent, Gaël Ennequin, Kévin Caillaud, Christophe Montaurier, Béatrice Morio, Nathalie Boisseau, Ruddy Richard

    2014-09-01

    Full Text Available The study of the physiological adaptations of skeletal muscle in response to eccentric (ECC contraction is based on protocols in which exercise intensities are determined relative to the concentric (CON reference exercise (as percentage of the CON maximal oxygen consumption, or VO2max. In order to use similar exercise protocols in rats, we compared the VO2 values during uphill (CON and downhill (ECC running tests. VO2 was measured in 15 Wistar rats during incremental treadmill running exercises with different slopes: level (0%, positive (+15% incline: CON+15% and negative (i15% incline: ECC-15%; and 130% incline: ECC-30%. Similar VO2 values were obtained in the ECC-30% and CON+15% running conditions at the three target speeds (15, 25 and 35 cm/sec. Conversely, VO2 values were lower (p < 0.05 in the ECC-15% than in the CON+15% condition (CON+15% VO2/ECC-15% VO2 ratios ranging from 1.86 to 2.05 at the three target speeds. Thus, doubling the downhill slope gradient in ECC condition leads to an oxygen consumption level that is not significantly different as in CON condition. These findings can be useful for designing animal research protocols to study the effects of ECC and CON exercise in ageing population or subjects suffering from cardiovascular diseases.

  17. Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells

    DEFF Research Database (Denmark)

    Møller, Henrik D.; Bojsen, Rasmus Kenneth; Tachibana, Chris

    2016-01-01

    for detecting eccDNA are needed to clarify how these elements affect genome stability and how environmental and biological factors induce their formation in eukaryotic cells. This video presents a sensitive eccDNA-purification method called Circle-Seq. The method encompasses column purification of circular DNA...... circularization is conserved between strains at these loci. In sum, the Circle-Seq method has broad applicability for genome-scale screening for eccDNA in eukaryotes as well as for detecting specific eccDNA types....

  18. Knee Extensor and Flexor Torque Development with Concentric and Eccentric Isokinetic Training

    Science.gov (United States)

    Miller, Larry E.; Pierson, Lee M.; Nickols-Richardson, Sharon M.; Wootten, David F.; Selmon, Serah E.; Ramp, Warren K.; Herbert, William G.

    2006-01-01

    This study assessed muscular torque and rate of torque development following concentric (CON) or eccentric (ECC) isokinetic training. Thirty-eight women were randomly assigned to either CON or ECC training groups. Training consisted of knee extension and flexion of the nondominant leg three times per week for 20 weeks (SD = 1). Eccentric training…

  19. Muscle fascicle behavior during eccentric cycling and its relation to muscle soreness.

    Science.gov (United States)

    Peñailillo, Luis; Blazevich, Anthony J; Nosaka, Kazunori

    2015-04-01

    A single bout of eccentric exercise confers a protective effect against muscle damage and soreness in subsequent eccentric exercise bouts, but the mechanisms underpinning this effect are unclear. This study compared vastus lateralis (VL) muscle-tendon behavior between two eccentric cycling bouts to test the hypothesis that muscle-tendon behavior would be different between bouts and would be associated with the protective effect. Eleven untrained men (27.1 ± 7.0 yr) performed two bouts of eccentric cycling (ECC1 and ECC2) separated by 2 wk for 10 min at 65% of maximal concentric workload (191.9 ± 44.2 W) each. Muscle soreness (by visual analog scale) and maximal voluntary isometric contraction (MVC) torque of the knee extensors were assessed before and 1-2 d after exercise. Using ultrasonography, VL fascicle length and angle changes during cycling were assessed, and tendinous tissue (TT) length changes were estimated. VL EMG amplitude, crank torque, and knee joint angles were measured during cycling. Soreness was greater (P knee angles were evident between bouts. However, fascicle elongation was 16% less during ECC2 than ECC1 (P knee joint angle during ECC2 than ECC1 (P = 0.055). These results suggest that a lesser fascicle elongation and earlier TT elongation were associated with reduced muscle soreness after ECC2 than ECC1; thus, changes in muscle-tendon behavior may be an important mechanism underpinning the protective effect.

  20. A Prototype of CAD/CAM Education in the Community College.

    Science.gov (United States)

    Kimmey, James R.

    Drawing upon Elgin Community College's (ECC's) 7-year history of program development and operation, this paper demonstrates how ECC, in cooperation with Northern Illinois Industries, Computervision Corporation, Mazak Corporation, and the Society of Manufacturing Engineers, established a Computer-Aided Design and Drafting/Computer-Aided Machining…

  1. Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells

    DEFF Research Database (Denmark)

    Møller, Henrik D.; Bojsen, Rasmus Kenneth; Tachibana, Chris;

    2016-01-01

    for detecting eccDNA are needed to clarify how these elements affect genome stability and how environmental and biological factors induce their formation in eukaryotic cells. This video presents a sensitive eccDNA-purification method called Circle-Seq. The method encompasses column purification of circular DNA...

  2. The Effects of Load and Effort-Matched Concentric and Eccentric Knee Extension Training in Recreational Females

    Directory of Open Access Journals (Sweden)

    Fisher James

    2014-09-01

    Full Text Available Purpose. The purpose of this study was to compare the effects of load and intensity of effort-matched concentric and eccentric knee extension training on isometric strength. Methods. Unilateral isometric torque was measured using a MedX knee extension after which eleven recreationally trained females performed both concentric-only (CONC and eccentric-only (ECC unilateral knee extension exercise once per week for 8 weeks. Participants performed a single set of both CONC and ECC exercise loadmatched at 80% of maximum isometric torque for each condition. All participants exercised to repetition maximum in both CONC and ECC conditions at a pace of ~3 s duration for each muscle action. This ensured that participants exercised to the same intensity of effort for both CONC and ECC training interventions. Results. Analyses revealed significant increases in isometric torque for both CONC (14.8% and ECC (13.0% conditions (p 0.05. Effect sizes are reported as 0.60 (CONC and 0.53 (ECC. In addition, analyses revealed significantly greater mean total training volume for ECC compared with CONC conditions (15903 vs. 8091, respectively; p < 0.001. Conclusions. The present findings indicate that, when matched for intensity of effort, both CONC and ECC knee extension exercise can significantly improve strength to the same extent. This supports previous research that load and repetitions are not as important as intensity of effort in resistance exercise.

  3. Knee Extensor and Flexor Torque Development with Concentric and Eccentric Isokinetic Training

    Science.gov (United States)

    Miller, Larry E.; Pierson, Lee M.; Nickols-Richardson, Sharon M.; Wootten, David F.; Selmon, Serah E.; Ramp, Warren K.; Herbert, William G.

    2006-01-01

    This study assessed muscular torque and rate of torque development following concentric (CON) or eccentric (ECC) isokinetic training. Thirty-eight women were randomly assigned to either CON or ECC training groups. Training consisted of knee extension and flexion of the nondominant leg three times per week for 20 weeks (SD = 1). Eccentric training…

  4. Mechanical, hormonal, and hypertrophic adaptations to 10 weeks of eccentric and stretch-shortening cycle exercise training in old males

    NARCIS (Netherlands)

    Vaczi, Mark; Nagy, Szilvia A.; Koszegi, Tamas; Ambrus, Mira; Bogner, Peter; Perlaki, Gabor; Orsi, Gergely; Toth, Katalin; Hortobagyi, Tibor

    2014-01-01

    The growth promoting effects of eccentric (ECC) contractions are well documented but it is unknown if the rate of stretch per se plays a role in such muscular responses in healthy aging human skeletal muscle. We tested the hypothesis that exercise training of the quadriceps muscle with low rate ECC

  5. The Worldwide Expansion of Early Childhood Care and Education, 1985-2010

    Science.gov (United States)

    Wotipka, Christine Min; Rabling, Brenda Jarillo; Sugawara, Minako; Tongliemnak, Pumsaran

    2017-01-01

    Although early childhood care and education (ECCE) enrollments have expanded significantly around the world since the 1960s, little is known about the economic, social, and cultural drivers explaining this growth. Using country fixed effects and a sample of 117 countries, this study explores three predictors framing the growth of ECCE enrollments…

  6. The Value of Endocervical Curettage in Addition to Biopsies in Women Referred to Colposcopy

    NARCIS (Netherlands)

    van der Marel, Jacolien; Rodriguez, Agata; del Pino, Marta; van Baars, Romy; Jenkins, David; van de Sandt, Miekel M.; Torne, Aureli; Ordi, Jaume; ter Harmsel, Bram; Verheijen, Rene H. M.; Schiffman, Mark; Gage, Julia C.; Quint, Wim G. V.; Wentzensen, Nicolas

    2015-01-01

    Objective Performing endocervical curettage (ECC) at colposcopy may increase the yield of cervical intraepithelial neoplasia grade 2 (CIN2) or worse (CIN2+) compared to biopsies alone. The additional benefit of ECC in detecting CIN2+ was studied in women with lesion-targeted biopsies (low-grade or w

  7. Better Planning and Oversight Could Have Reduced Construction Delays and Costs at the Kabul Military Training Center

    Science.gov (United States)

    2011-10-26

    Representative CSTC-A Combined Security Transition Command - Afghanistan DNC Discrepancy and Non-Compliance DPW Department of Public Works ECC ECC...Discrepancy and Non-Compliance ( DNC ) log, stating that SIGAR Audit-12-2 Contractor Performance and Oversight / Kabul Military Training Center Page 15

  8. Unpacking the Treatment Contrast in the Head Start Impact Study: To What Extent Does Assignment to Treatment Affect Quality of Care?

    Science.gov (United States)

    Friedman-Krauss, Allison H.; Connors, Maia C.; Morris, Pamela A.

    2017-01-01

    Attending high-quality early childhood care and education (ECCE) is associated with higher cognitive and social-emotional skills, especially for children growing up in poverty, but access to high-quality ECCE is limited. This study capitalizes on the random assignment design of the Head Start Impact Study to better understand whether the…

  9. Efficient Implementation of Elliptic Curve Cryptography Using Low-power Digital Signal Processor

    CERN Document Server

    Malik, Muhammad Yasir

    2011-01-01

    RSA(Rivest, Shamir and Adleman)is being used as a public key exchange and key agreement tool for many years. Due to large numbers involved in RSA, there is need for more efficient methods in implementation for public key cryptosystems. Elliptic Curve Cryptography(ECC) is based on elliptic curves defined over a finite field. Elliptic curve cryptosystems(ECC) were discovered by Victor Miller and Neal Koblitz in 1985.This paper comprises of five sections. Section I is introduction to ECC and its components. Section II describes advantages of ECC schemes and its comparison with RSA. Section III is about some of the applications of ECC. Section IV gives some embedded implementations of ECC. Section V contains ECC implementation on fixed point Digital Signal Processor(TMS320VC5416). ECC was implemented using general purpose microcontrollers and Field Programmable Gate Arrays (FPGA) before this work. DSP is more powerful than microcontrollers and much economical than FPGA. So this implementation can be efficiently u...

  10. Phenomenological interpretation of the shear behavior of reinforced Engineered Cementitious Composite beams

    DEFF Research Database (Denmark)

    Paegle, Ieva; Fischer, Gregor

    2016-01-01

    This paper describes an experimental investigation of the shear behavior of beams consisting of steel Reinforced Engineered Cementitious Composites (R/ECC). This study investigates and quantifies the effect of ECC's strain hardening and multiple cracking behavior on the shear capacity of beams lo...

  11. Shear crack formation and propagation in reinforced Engineered Cementitious Composites

    DEFF Research Database (Denmark)

    Paegle, Ieva; Fischer, Gregor

    2011-01-01

    capacity of beams loaded primarily in shear. The experimental program consists of ECC with short randomly distributed polyvinyl alcohol (PVA) fiber beams with different stirrup arrangements and conventional reinforced concrete (R/C) counterparts for comparison. The shear crack formation mechanism of ECC...

  12. Strategies for Implementation: The El Camino TQM Story.

    Science.gov (United States)

    Schauerman, Sam; Peachy, Burt

    In spring 1989, a group of 33 administrators, supervisors, faculty, and staff from El Camino College (ECC) in Torrance, California, attended 10 days of training in Total Quality Management (TQM) tools and techniques. The subsequent implementation of TQM at ECC included the following six phases: (1) establishing a Campus Commitment to Excellence…

  13. Mechanical, hormonal, and hypertrophic adaptations to 10 weeks of eccentric and stretch-shortening cycle exercise training in old males

    NARCIS (Netherlands)

    Vaczi, Mark; Nagy, Szilvia A.; Koszegi, Tamas; Ambrus, Mira; Bogner, Peter; Perlaki, Gabor; Orsi, Gergely; Toth, Katalin; Hortobagyi, Tibor

    2014-01-01

    The growth promoting effects of eccentric (ECC) contractions are well documented but it is unknown if the rate of stretch per se plays a role in such muscular responses in healthy aging human skeletal muscle. We tested the hypothesis that exercise training of the quadriceps muscle with low rate ECC

  14. 77 FR 50533 - Dominion Nuclear Connecticut, Inc.; Millstone Power Station, Unit 3

    Science.gov (United States)

    2012-08-21

    ... the ECCS for reactors that have fuel rods fabricated either with Zircaloy or ZIRLO\\TM\\. Appendix K to... systems for light-water nuclear power reactors,'' and Appendix K to 10 CFR Part 50, ``ECCS Evaluation Models,'' to allow the use of Optimized ZIRLO\\TM\\ fuel rod cladding in future core reload...

  15. Early Childhood Caries: Prevalence, Risk Factors, and Prevention

    Directory of Open Access Journals (Sweden)

    Sukumaran Anil

    2017-07-01

    Full Text Available Early childhood caries (ECC is major oral health problem, mainly in socially disadvantaged populations. ECC affects infants and preschool children worldwide. The prevalence of ECC differs according to the group examined, and a prevalence of up to 85% has been reported for disadvantaged groups. ECC is the presence of one or more decayed, missing, or filled primary teeth in children aged 71 months (5 years or younger. It begins with white-spot lesions in the upper primary incisors along the margin of the gingiva. If the disease continues, caries can progress, leading to complete destruction of the crown. The main risk factors in the development of ECC can be categorized as microbiological, dietary, and environmental risk factors. Even though it is largely a preventable condition, ECC remains one of the most common childhood diseases. The major contributing factors for the for the high prevalence of ECC are improper feeding practices, familial socioeconomic background, lack of parental education, and lack of access to dental care. Oral health plays an important role in children to maintain the oral functions and is required for eating, speech development, and a positive self-image. The review will focus on the prevalence, risk factors, and preventive strategies and the management of ECC.

  16. Early Child Care and Education: HHS and Education Are Taking Steps to Improve Workforce Data and Enhance Worker Quality. Report to the Chairman, Committee on Finance, U.S. Senate. GAO-12-248

    Science.gov (United States)

    Brown, Kay E.

    2012-01-01

    Research shows that well trained and educated early child care and education (ECCE) workers are key to helping children in care reach their full developmental potential. Federal and state governments spend billions of dollars each year to improve ECCE programs, including the quality of its caregivers and teachers. Because of the importance of this…

  17. Reducing Early Childhood Tooth Decay: Strategies for State Medicaid and CHIP Dental Program Managers

    OpenAIRE

    2015-01-01

    Young children who are enrolled in Medicaid or the Children’s Health Insurance Program (CHIP) can be at risk for developing early childhood caries (ECC). ECC is a chronic bacterial infection that causes severe tooth decay and can begin to develop before baby teeth erupt.

  18. Genome-wide Purification of Extrachromosomal Circular DNA from Eukaryotic Cells.

    Science.gov (United States)

    Møller, Henrik D; Bojsen, Rasmus K; Tachibana, Chris; Parsons, Lance; Botstein, David; Regenberg, Birgitte

    2016-04-04

    Extrachromosomal circular DNAs (eccDNAs) are common genetic elements in Saccharomyces cerevisiae and are reported in other eukaryotes as well. EccDNAs contribute to genetic variation among somatic cells in multicellular organisms and to evolution of unicellular eukaryotes. Sensitive methods for detecting eccDNA are needed to clarify how these elements affect genome stability and how environmental and biological factors induce their formation in eukaryotic cells. This video presents a sensitive eccDNA-purification method called Circle-Seq. The method encompasses column purification of circular DNA, removal of remaining linear chromosomal DNA, rolling-circle amplification of eccDNA, deep sequencing, and mapping. Extensive exonuclease treatment was required for sufficient linear chromosomal DNA degradation. The rolling-circle amplification step by φ29 polymerase enriched for circular DNA over linear DNA. Validation of the Circle-Seq method on three S. cerevisiae CEN.PK populations of 10(10) cells detected hundreds of eccDNA profiles in sizes larger than 1 kilobase. Repeated findings of ASP3-1, COS111, CUP1, RSC30, HXT6, HXT7 genes on circular DNA in both S288c and CEN.PK suggests that DNA circularization is conserved between strains at these loci. In sum, the Circle-Seq method has broad applicability for genome-scale screening for eccDNA in eukaryotes as well as for detecting specific eccDNA types.

  19. Evolution of the Early Childhood Curriculum in China: The Impact of Social and Cultural Factors on Revolution and Innovation

    Science.gov (United States)

    Li, Hui; Chen, Jennifer J.

    2017-01-01

    During the last century, early childhood curriculum (ECC) in China has undergone a series of monumental transformations, shaped by the interaction between local cultural and global forces. In this case study, we critically analyse three major waves of ECC reform in China, with a particular emphasis on the social and cultural forces that have…

  20. A Plastic Damage Mechanics Model for Engineered Cementitious Composites

    DEFF Research Database (Denmark)

    Dick-Nielsen, Lars; Stang, Henrik; Poulsen, Peter Noe

    2007-01-01

    This paper discusses the establishment of a plasticity-based damage mechanics model for Engineered Cementitious Composites (ECC). The present model differs from existing models by combining a matrix and fiber description in order to describe the behavior of the ECC material. The model provides in...

  1. Nueva aportación a la obra de Morales: cronología, soportes y réplicas

    Directory of Open Access Journals (Sweden)

    Mateo Gómez, Isabel

    2015-06-01

    Full Text Available The author studies three new versions of the Ecce Homo, painted on different supports, and a replica of the Mary Magdalene from the Clerecía of Salamanca.Se aportan tres nuevas versiones del Ecce Homo, pintados sobre distinto soporte, y una Magdalena, réplica de la tabla de la Clerecía de Salamanca.

  2. Impact Properties of Engineered Cementitious Composites with High Volume Fly Ash Using SHPB Test

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhitao; YANG Yingzi; YAO Yan

    2012-01-01

    The split Hopkinson pressure bar (SHPB) testing with diameter 40 mm was used to investigate the dynamic mechanical properties of engineered cementitious composites (ECCs) with different fly ash content.The basic properties including deformation,energy absorption capacity,strain-stress relationship and failure patterns were discussed.The ECCs showed strain-rate dependency and kept better plastic flow during impact process compared with reactive powder concrete (RPC) and concrete,but the critical compressive strength was lower than that of R-PC and concrete.The bridging effect of PVA fiber and addition of fly ash can significantly improve the deformation and energy absorption capacities of ECCs.With the increase of fly ash content in ECCs,the static and dynamic compressive strength lowered and the dynamic increase factor enhanced,Therefore,to meet different engineering needs,the content of fly ash can be an important index to control the static and dynamic mechanical properties of ECCs.

  3. Strain and Cracking Surveillance in Engineered Cementitious Composites by Piezoresistive Properties

    Directory of Open Access Journals (Sweden)

    Jia Huan Yu

    2010-01-01

    Full Text Available Engineered Cementitious Composites (ECCs are novel cement-based ultraductile materials which is crack resistant and undergoes strain hardening when loaded in tension. In particular, the material is piezoresistive with changes in electrical resistance correlated with mechanical strain. The unique electrical properties of ECC render them a smart material capable of measuring strain and the evolution of structural damage. In this study, the conductivity of the material prior to loading was quantified. The piezoresistive property of ECC structural specimens are exploited to directly measure levels of cracking pattern and tensile strain. Changes in ECC electrical resistance are measured using a four-probe direct-current (DC resistance test as specimens are monotonically loaded in tension. The change in piezoresistivity correlates the cracking and strain in the ECC matrix and results in a nonlinear change in the material conductivity.

  4. Analysis of the Use of Extracorporeal Circulation on the In-Hospital Outcomes of Dialytic Patients Who Underwent Myocardial Revascularization Surgery

    Science.gov (United States)

    Miranda, Matheus; Branco, João Nelson Rodrigues; Vargas, Guilherme Flora; Hossne Jr, Nelson Americo; Yoshimoto, Michele Costa; da Fonseca, José Honorio de Almeida Palma; Pestana, José Osmar Medina de Abreu; Buffolo, Enio

    2016-01-01

    Background Myocardial revascularization surgery is the best treatment for dyalitic patients with multivessel coronary disease. However, the procedure still has high morbidity and mortality. The use of extracorporeal circulation (ECC) can have a negative impact on the in-hospital outcomes of these patients. Objectives To evaluate the differences between the techniques with ECC and without ECC during the in-hospital course of dialytic patients who underwent surgical myocardial revascularization. Methods Unicentric study on 102 consecutive, unselected dialytic patients, who underwent myocardial revascularization surgery in a tertiary university hospital from 2007 to 2014. Results Sixty-three patients underwent surgery with ECC and 39 without ECC. A high prevalence of cardiovascular risk factors was found in both groups, without statistically significant difference between them. The group "without ECC" had greater number of revascularizations (2.4 vs. 1.7; p <0.0001) and increased need for blood components (77.7% vs. 25.6%; p <0.0001) and inotropic support (82.5% vs 35.8%; p <0.0001). In the postoperative course, the group "without ECC" required less vasoactive drugs, (61.5% vs. 82.5%; p = 0.0340) and shorter time of mechanical ventilation (13.0 hours vs. 36,3 hours, p = 0.0217), had higher extubation rates in the operating room (58.9% vs. 23.8%, p = 0.0006), lower infection rates (7.6% vs. 28.5%; p = 0.0120), and shorter ICU stay (5.2 days vs. 8.1 days; p = 0.0054) as compared with the group with ECC surgery. No difference in mortality was found between the groups. Conclusion Myocardial revascularization with ECC in patients on dialysis resulted in higher morbidity in the perioperative period in comparison with the procedure without ECC, with no difference in mortality though.

  5. The prevalence of Early Childhood Caries in 1-2 yrs olds in a semi-urban area of Sri Lanka

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    Jayasekara Prasanna

    2011-09-01

    Full Text Available Abstract Background ECC remains a problem in both developed and developing countries and ECC has been considered to be present in epidemic proportions in the developing countries. The aetiology and associated factors of ECC should be studied adequately to overcome this health hazard. The objective of this study is to determine the prevalence of ECC in 1 to 2 years old children in some selected MOH areas (semi-urban in the district of Colombo, Sri Lanka. Methods This study was conducted as a cross sectional study. A total of 422 children aged 1-2 years were selected using systematic sampling technique in Maharagama, Piliyandala, Nugegoda and Boralesgamuwa MOH areas in Colombo district, Western province, Sri Lanka. The pre-test was done initially with 10 children aged 1 1/2 year olds. Prior to the clinical examination of each child, a questionnaire consisting questions regarding tooth brushing, dietary habits, breast and bottle feeding, long term medications(Sweetened medications taken more than 3 months, attending a dental clinic during pregnancy of mother and socio-economical status of the family was administered to mothers of those children. Sterile dental mouth mirrors were used to detect ECC in children. Results The prevalence of ECC of the whole sample of 410 children aged 1-2 years was 32.19% and the mean dmft was 2.01 and the mean dmfs was 3.83. From the children who had ECC 95% were untreated. There were significant relationships between dmft and long term use of medications (p Conclusions This study documents high prevalence and severity of ECC among 1-2 years old children in four selected MOH areas of Colombo district and caries in most of the children with ECC (95% were untreated. Results reveal an urgent need to increase awareness among the public about ECC and institute preventive strategies.

  6. Analysis of the Use of Extracorporeal Circulation on the In-Hospital Outcomes of Dialytic Patients Who Underwent Myocardial Revascularization Surgery

    Directory of Open Access Journals (Sweden)

    Matheus Miranda

    Full Text Available Abstract Background: Myocardial revascularization surgery is the best treatment for dyalitic patients with multivessel coronary disease. However, the procedure still has high morbidity and mortality. The use of extracorporeal circulation (ECC can have a negative impact on the in-hospital outcomes of these patients. Objectives: To evaluate the differences between the techniques with ECC and without ECC during the in-hospital course of dialytic patients who underwent surgical myocardial revascularization. Methods: Unicentric study on 102 consecutive, unselected dialytic patients, who underwent myocardial revascularization surgery in a tertiary university hospital from 2007 to 2014. Results: Sixty-three patients underwent surgery with ECC and 39 without ECC. A high prevalence of cardiovascular risk factors was found in both groups, without statistically significant difference between them. The group "without ECC" had greater number of revascularizations (2.4 vs. 1.7; p <0.0001 and increased need for blood components (77.7% vs. 25.6%; p <0.0001 and inotropic support (82.5% vs 35.8%; p <0.0001. In the postoperative course, the group "without ECC" required less vasoactive drugs, (61.5% vs. 82.5%; p = 0.0340 and shorter time of mechanical ventilation (13.0 hours vs. 36,3 hours, p = 0.0217, had higher extubation rates in the operating room (58.9% vs. 23.8%, p = 0.0006, lower infection rates (7.6% vs. 28.5%; p = 0.0120, and shorter ICU stay (5.2 days vs. 8.1 days; p = 0.0054 as compared with the group with ECC surgery. No difference in mortality was found between the groups. Conclusion: Myocardial revascularization with ECC in patients on dialysis resulted in higher morbidity in the perioperative period in comparison with the procedure without ECC, with no difference in mortality though.

  7. Psychosocial factors and early childhood caries among low-income African-American children in Detroit.

    Science.gov (United States)

    Finlayson, Tracy L; Siefert, Kristine; Ismail, Amid I; Sohn, Woosung

    2007-12-01

    This study sought to advance knowledge of the social determinants of oral health, by examining how several specific maternal health beliefs, behaviors, and psychosocial factors relate to young children's early childhood caries (ECC) status in a lower-income African-American population. Data were collected by the Detroit Dental Health Project (NIDCR grant), a population-based study of 1021 African-American families with at least one child under 6 years of age and living in 39 low-income Census tracts in Detroit, Michigan. Analyses were limited to 719 children aged 1-5 years and their biological mothers, and conducted in SUDAAN to account for the complex sampling design. Survey data included health belief scales on mothers' self-efficacy, feelings of fatalism, knowledge about appropriate bottle use and children's oral hygiene needs, brushing habits, psychosocial measures of depressive symptoms (CES-D), parenting stress, and availability of instrumental social support. The child's age, dental insurance status, dental visit history, and 1-week brushing frequency were also included in the model. Children's ECC status, based on a dental examination, was the main outcome. The dental team used the International Caries Detection and Assessment System (ICDAS) criteria for caries detection. Each child was classified as either caries-free or having ECC or severe ECC (S-ECC) based on the case definition of ECC proposed by an expert panel for research purposes with preschool-aged children. The dental team followed a specific examination protocol and established reliable and consistent ratings of ECC based on the ICDAS criteria. The inter-rater reliability kappa was 0.83 overall, and the intra-rater reliability kappa was 0.74 overall. One-third of the children had ECC, and 20% had severe ECC. Age of the child and lower parenting stress scores were each positively associated with ECC, while higher education and income were protective. Maternal oral health fatalism and knowledge of

  8. Investigation of and Policy Recommendations to ECCE at Rural Poverty-stricken Regions——taking N town of a poverty-stricken county in central China as a case%农村贫困地区幼儿保育和教育现状及其发展政策建议——以中部某省某国家级贫困县N镇为个案

    Institute of Scientific and Technical Information of China (English)

    张家勇; 朱玉华; 肖毅

    2010-01-01

    农村贫困地区的幼儿保育和教育工作是我国实现全民教育目标所面临的最大难点.本研究选取我国中部某国家级贫困县N镇作为个案,以联合国教科文组织亚太办事处列出的21项"幼儿保育和教育"指标为基本框架,采取个人访谈、文献收集和现场观察等方法对农村贫困地区幼儿保育和教育工作开展现状展开全面调查.结果显示,N镇的幼儿保育现状和幼儿教育现状都十分不容乐观,存在的主要问题包括留守幼儿保育状况令人担忧;祖辈们的保育知识匮乏,保育方式不科学;幼儿保育医疗卫生条件差;幼儿园任课教师专业合格率偏低;幼儿园教育小学化倾向严重;地方政府对幼儿教育缺乏重视.造成这些问题的根源主要是我国现有相关法律法规不完善,管理体制存在弊端,幼儿教师农村就业渠道不畅.为促进我国农村贫困地区幼儿保育与教育工作的发展,应尽快制定内容完整的,完善我国幼儿保育与教育治理结构,重建其投资体制,加大中央政府与省级政府的投入职责,在政府引导下构建多种共同促进幼儿保育与教育工作发展的伙伴关系.

  9. Molecular cloning, characterization and expression analysis of complement component C8 beta in the orange-spotted grouper (Epinephelus coioides) after the Vibrio alginolyticus challenge.

    Science.gov (United States)

    Luo, Shengwei; Xie, Fuxing; Liu, Yuan; Wang, Wei-Na

    2015-03-10

    Complement component C8 beta was a key molecule in the complement system, mediating the MAC formation and the bacterial lysis. In this study, the full-length C8 beta (EcC8 beta) was obtained, containing a 5'UTR of 25 bp, an ORF of 1764 bp and a 3'UTR of 198 bp. The EcC8 beta gene encoded a protein of 587 amino acids with an estimated molecular mass of 65.87 kDa and a predicted isoelectric point (pI) of 6.35. The deduced amino acid sequence showed that EcC8 beta consisted of the conserved residues and the domains known to be critical for C8 beta function. The quantitative real-time PCR analysis revealed that EcC8 beta transcript was expressed in all the examined tissues, while the strong expression was observed in the liver. In addition, complement C3 was the central molecule in the complement system, converging the upstream complement signals and mediating the MAC assembly pathway, while C8 beta was indispensable for active MAC formation. Following the Vibrio challenge, the increased expression of EcC3 transcript and EcC8 beta transcript was observed in the liver and kidney. These results indicated that EcC8 beta may be an important immune-related gene, playing an important role in the immune defense against the bacterial infection via the complement pathway.

  10. Low-intensity eccentric contractions attenuate muscle damage induced by subsequent maximal eccentric exercise of the knee extensors in the elderly.

    Science.gov (United States)

    Chen, Trevor C; Tseng, Wei-Chin; Huang, Guan-Ling; Chen, Hsin-Lian; Tseng, Kou-Wei; Nosaka, Kazunori

    2013-04-01

    This study investigated whether low-intensity eccentric contractions of the knee extensors would attenuate the magnitude of muscle damage induced by maximal eccentric exercise of the same muscle performed 7 days later using elderly individuals. Healthy older men (66.4 ± 4.6 years) were assigned to control or experimental (Exp) group (n = 13 per group). The control group performed six sets of ten maximal eccentric contractions (MaxECC) of the knee extensors of non-dominant leg. The Exp group performed six sets of ten low-intensity eccentric contractions of the knee extensors on a leg extension machine by lowering a weight of 10 % maximal voluntary isometric knee extension strength (10 %ECC) 7 days prior to MaxECC. Changes in maximal voluntary isokinetic concentric torque (MVC-CON), angle at peak torque, range of motion (ROM), upper thigh circumference, muscle soreness, plasma creatine kinase activity and myoglobin (Mb) concentration and B-mode ultrasound echo-intensity before and for 5 days after MaxECC were compared between groups by a mixed factor ANOVA. No significant changes in any variables were observed following 10 %ECC. Following MaxECC, all variables changed significantly, and changes in all variables except for angle at peak torque were significantly different between groups. MVC-CON and ROM decreased smaller and recovered faster (P eccentric contractions was effective for attenuating muscle damage induced by subsequent MaxECC of the knee extensors for elderly individuals.

  11. Parenting style and oral health practices in early childhood caries: a case-control study.

    Science.gov (United States)

    Dabawala, Suhel; Suprabha, Baranya S; Shenoy, Ramya; Rao, Arathi; Shah, Nachiket

    2017-03-01

    There is a need to carry out controlled investigations regarding risk factors for early childhood caries (ECC). To study the type of parenting style and oral health practices as risk factors among children with ECC in an Indian preschool population. Two hundred and eleven children with ECC and equal number of controls participated in this case-control study. A questionnaire was answered by parents regarding oral health practices such as oral hygiene methods, feeding habits, daily sugar intake, and dental attendance pattern along with socioeconomic and demographic status. The parenting style was determined using Parenting Styles Dimension Questionnaire (PSDQ) index. Data were statistically analyzed using chi-square test and multiple logistic regression analysis. Risk factors associated with ECC were higher birth order, lower socioeconomic status, non-use of fluoridated toothpaste, breast/bottle feeding for more than one year, presence of formula milk or milk with sugar in the feeding bottle while falling asleep, higher sweet scores in the diet chart, and visiting dentist only when a problem was perceived. Majority of parents of children with and without ECC had authoritative parenting style. Improper oral health practices are the risk factors for ECC. The association of parenting style with ECC could not be confirmed. © 2016 BSPD, IAPD and John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Chronic Disease Management Strategies of Early Childhood Caries: Support from the Medical and Dental Literature.

    Science.gov (United States)

    Edelstein, Burton L; Ng, Man Wai

    2015-01-01

    An Institute of Medicine report places chronic disease management (CDM) as an intervention on a treatment spectrum between prevention and acute care. CDM commonly focuses on conditions in which patient self-care efforts are significant. Framing early childhood caries (ECC) as such a chronic condition invites dentistry to reconsider its approach to caries management and shift gears from a strictly surgical approach to one that also incorporates a medical approach. This paper's purpose was to explore the definition of and concepts inherent in CDM. An explanatory model is introduced to describe the multiple factors that influence ECC-CDM strategies. Reviewed literature suggests that early evidence from ECC-CDM interventions, along with results of pediatric asthma and diabetes CDM, supports CDM of ECC as a valid approach that is independent of both prevention and repair. Early results of ECC-CDM endeavors have demonstrated a reduction in rates of new cavitation, dental pain, and referral to the operating room compared to baseline rates. ECC-CDM strategies hold strong promise to curtail caries activity while complementing dental repair when needed, thereby reducing disease progression and cavity recurrence. Institutionalizing ECC-CDM will both require and benefit from evolving health care delivery and financing systems that reward positive health outcomes.

  13. Comparison between Clinical Aspects and Salivary Microbial Profile of Children with and without Early Childhood Caries: A Preliminary Study.

    Science.gov (United States)

    Neves, A B; Lobo, L A; Pinto, K C; Pires, E S; Requejo, Mep; Maia, L C; Antonio, A G

    2015-01-01

    To compare the clinical aspects and microbial profile of children with and without early childhood caries (ECC). 14 patients (7 without caries and 7 with ECC) were submitted to anamnesis, clinical exam and saliva collection for microbiological analyses. Counts of Streptococcus mutans, Lactobacillus spp. Candida spp., and total microorganisms were performed by culture methods. Microbial diversity was characterized by PCR-DGGE. Demographic/clinical data and salivary microbial counts were compared between groups. Habits of hygiene and breastfeeding presented no association with ECC. Use of pacifiers was associated with absence of caries (p=0.035). Counts of total microorganisms and Candida spp. did not differ between the groups. The ECC group presented larger quantity of S. mutans (p=0.026) and Lactobacillus spp. (p=0.002). There was no correlation between microorganisms and breastfeeding and pacifier use. The dmf-t of ECC Group was 10.5 ± 1.9 and the modified dmf-t was 11.3 ± 3.6. The DGGE demonstrated difference in the pattern of bands between the groups. Pacifiers usage was associated with the absence of ECC and microorganism number was higher in the caries group. The PCR-DGGE revealed a characteristic microbial diversity in the ECC Group, being an excellent tool for observing the dynamics of the salivary microbial community in these patients.

  14. Hepatic dysfunction contributes to coagulation disturbances in patients undergoing whole body hyperthermia by use of extracorporeal circulation.

    Science.gov (United States)

    Worel, Nina; Knöbl, Paul; Karanikas, Georgios; Fuchs, Eva-Maria; Bojic, Andja; Brodowicz, Thomas; Jilma, Petra; Zielinski, Christoph C; Köstler, Wolfgang J; Locker, Gottfried J

    2014-09-01

    This phase I study was performed to evaluate coagulation alterations during extracorporeal circulation (ECC) induced whole body hyperthermia (WBHT) in 12 patients with advanced soft tissue sarcomas. To distinguish between effects of normothermic ECC and ECC-WBHT, blood samples were drawn at different time points: at baseline, after 30 min on normothermic ECC, at the end of the heating period, and 24 h and 7 days thereafter. Standard coagulation tests, coagulation factors, thrombelastography,platelets and reticulated platelets, liver enzymes, and scintigraphic platelet imaging were performed. Normothermic ECC resulted in coagulation alterations most likely due to systemic anticoagulation. Induction of hyperthermia caused thrombocytopenia, increased fibrin degradation products,prolonged clotting times, alteration in coagulation factors, and increased liver enzymes. The majority of these effects was most pronounced 24 h after ECC-WBHT. In addition, late liver sequestration of platelets was demonstrated in scintigraphic imaging at that time point. Temporal correlation between hemostatic alterations and elevation in liver enzymes leads to the assumption that liver impairment might play a crucial role in coagulation disturbances observed during ECC-WBHT and thereafter, thus strongly supported by liver sequestration of platelets.Therefore a close monitoring of hepatic derived coagulation alterations in patients undergoing extracorporeal whole body hypothermia is warranted.

  15. Safety and Efficacy of the Transition from Extracapsular Cataract Extraction to Manual Small Incision Cataract Surgery in Prevention of Blindness Campaigns.

    Science.gov (United States)

    Signes-Soler, Isabel; Javaloy, Jaime; Muñoz, Gonzalo; Moya, Tomas; Montalbán, Raúl; Albarrán, César

    2016-01-01

    To compare the safety and the visual outcomes of two experienced cataract surgeons who converted from extracapsular cataract extraction (ECCE) to manual small incision cataract surgery (MSICS) during a campaign for the prevention of blindness. Two surgeons used the ECCE technique (ECCE group) during a campaign in Burkina Faso on 93 consecutive cataract patients with a corrected distance visual acuity (CDVA) ECCE group. Spherical equivalents ranged between -1D and +1D in 55% of the MSICS group versus 43% in the ECCE group. There were significant differences in the changes in the vertical component of astigmatism (J45) but not the horizontal (J0) component. There were no significant differences in the intraoperative complications. The most common postoperative complication was corneal edema on the first day in 40.86% and 19.38% of the ECCE and MSICS groups, respectively. Transitioning from ECCE to MSICS for experienced cataract surgeons in surgical campaigns is safe. The rate of complications is similar for both techniques. Slightly better visual and refractive outcomes can be achieved due to the decreased induction of corneal astigmatism.

  16. Vitreous loss during conversion from conventional extracapsular cataract extraction to phacoemulsification.

    Science.gov (United States)

    Ah-Fat, F G; Sharma, M K; Majid, M A; Yang, Y C

    1998-06-01

    To study the outcome of vitreous loss among senior surgeons converting from conventional extracapsular cataract extraction (ECCE) to phacoemulsification. A university teaching hospital in the United Kingdom. A retrospective analysis of 87 planned cataract extractions performed from January 1992 to December 1996 and complicated by vitreous loss was done. Outcome measures included postoperative complication rates and visual acuity. During the study, vitreous loss occurred in 39 patients having ECCE and in 48 having phacoemulsification; the latter group included 8 patients with dropped nucleus. Postoperative complications included cystoid macular edema (18.7% of phaco patients, 30.8% of ECCE patients), retinal detachment (2.1% of phaco patients, 5.1% of ECCE patients), and expulsive hemorrhage (5.1% of ECCE patients). Phaco patients had higher rates of postoperative corneal edema (27.1%) than ECCE patients (12.8%) and transient intraocular pressure elevation (33.3%) versus 20.5%) but were more likely to receive posterior chamber intraocular lenses (70.8% versus 35.9%; P = .0024, chi-square test). After excluding pre-existing diseases, 83.3% of phaco patients and 67.6% of ECCE patients achieved a visual acuity of 6/12 or better. With careful patient selection, experienced extracapsular surgeons converting to phacoemulsification can achieve favorable results even in the presence of complications such as vitreous loss or dropped nucleus.

  17. Effects of Cataract Surgery on Endothelium in Transplanted Corneal Grafts: Comparison of Extracapsular Cataract Extraction and Phacoemulsification for Complicated Cataract after Penetrating Keratoplasty.

    Science.gov (United States)

    Zhou, Hong-Wei; Xie, Li-Xin

    2016-09-05

    The endothelium should be carefully evaluated when choosing a surgical technique for cataract removal. Therefore, we aimed to study the effects of different cataract surgery techniques on endothelial cell loss in transplanted corneal grafts. A total of 54 patients who received complicated cataract surgery in post-penetrating keratoplasty (PKP) eyes at the Shandong Eye Institute between February 2001 and June 2014 were included, and clinical records were reviewed. Baseline demographic details, clinical characteristics, endothelial cell density (ECD), and best-corrected visual acuity (BCVA) were recorded. Wilcoxon rank-sum test and Wilcoxon signed-rank test were used to test the equality of medians. A regression model was constructed to compare the reduced rate of ECD. Of the 54 eyes included in this study, extracapsular cataract extraction (ECCE) was performed in 34 eyes of 33 patients (ECCE group) whereas phacoemulsification was performed in 20 eyes of 20 patients (phacoemulsification group). There was no significant difference in the median age (P = 0.081) or preoperative ECD (P = 0.585) between the two groups. At 6 months after cataract surgery, ECD in ECCE group was significantly higher than that in phacoemulsification group (P = 0.043). In addition, the endothelial cell loss rate in ECCE group was significantly lower than that in phacoemulsification group at 2 months (P = 0.018), 4 months (P ECCE group (P ECCE in transplanted corneal grafts (P ECCE is more suitable than phacoemulsification in cataract surgery in complicated cataract after PKP.

  18. Relationship between Scanning Laser Polarimetry with Enhanced Corneal Compensation and with Variable Corneal Compensation

    Science.gov (United States)

    Kim, Kyung Hoon; Choi, Jaewan; Lee, Chang Hwan; Cho, Beom-Jin; Kook, Michael S.

    2008-01-01

    Purpose To evaluate the structure-function relationships between retinal sensitivity measured by Humphrey visual field analyzer (HVFA) and the retinal nerve fiber layer (RNFL) thickness measured by scanning laser polarimetry (SLP) with variable corneal compensation (VCC) and enhanced corneal compensation (ECC) in glaucomatous and healthy eyes. Methods Fifty-three eyes with an atypical birefringence pattern (ABP) based on SLP-VCC (28 glaucomatous eyes and 25 normal healthy eyes) were enrolled in this cross-sectional study. RNFL thickness was measured by both VCC and ECC techniques, and the visual field was examined by HVFA with 24-2 full-threshold program. The relationships between RNFL measurements in superior and inferior sectors and corresponding retinal mean sensitivity were sought globally and regionally with linear regression analysis in each group. Coefficients of the determination were calculated and compared between VCC and ECC techniques. Results In eyes with ABP, R2 values for the association between SLP parameters and retinal sensitivity were 0.06-0.16 with VCC, whereas they were 0.21-0.48 with ECC. The association of RNFL thickness with retinal sensitivity was significantly better with ECC than with VCC in 5 out of 8 regression models between SLP parameters and HVF parameters (P<0.05). Conclusions The strength of the structure-function association was higher with ECC than with VCC in eyes with ABP, which suggests that the ECC algorithm is a better approach for evaluating the structure-function relationship in eyes with ABP. PMID:18323701

  19. Prevalence of Early Childhood Caries and its Risk Factors in 6-60 months old Children in Quchan

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    Fatemeh Mazhari

    2007-01-01

    Full Text Available Introduction: Despite advances in the oral health of children in recent decades, early childhood caries (ECC continues to pose a serious threat to child welfare. The purpose of this study was to determine prevalence and severity of ECC in 6-60 month old children in relation to socioeconomic factors, feeding practices and oral health behaviors in Quchan.Materials and Methods: This cross-sectional study included almost all children enrolled in Quchans day care centers; 232 six to sixty months children were examined. Social and behavioral information were obtained from parents through a self-administered questionnaire. ECC and severe ECC (S-ECC were diagnosed based on NIDCR and WHO recommendations.Results: The prevalence of ECC and S-ECC were 59% and 25%, respectively. The overall mean of d2mfs (with cavitated carious surface lesions and d2psmfs (with cavitated and non-cavitated carious surface lesions were 2.1 ± 4.45 and 3.80 ± 5.34, respectively. The variables significantly associated with ECC or SECC were socioeconomic status, frequency of bottle-feeding, snacking frequency, probable age of starting tooth brushing, person responsible for child’s oral health care and eruption age of the first tooth.Conclusion: This study demonstrated that the prevalence of ECC was high among of preschool children in the city of Quchan. It is recommended to increase knowledge of parents about proper feeding habits and oral health practices, and also preschool children accessibility to dental services.

  20. Peripapillary retinal nerve fiber layer assessment of spectral domain optical coherence tomography and scanning laser polarimetry to diagnose preperimetric glaucoma.

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    Harsha L Rao

    Full Text Available To compare the abilities of peripapillary retinal nerve fiber layer (RNFL parameters of spectral domain optical coherence tomograph (SDOCT and scanning laser polarimeter (GDx enhanced corneal compensation; ECC in detecting preperimetric glaucoma.In a cross-sectional study, 35 preperimetric glaucoma eyes (32 subjects and 94 control eyes (74 subjects underwent digital optic disc photography and RNFL imaging with SDOCT and GDx ECC. Ability of RNFL parameters of SDOCT and GDx ECC to discriminate preperimetric glaucoma eyes from control eyes was compared using area under receiver operating characteristic curves (AUC, sensitivities at fixed specificities and likelihood ratios (LR.AUC of the global average RNFL thickness of SDOCT (0.786 was significantly greater (p<0.001 than that of GDx ECC (0.627. Sensitivities at 95% specificity of the corresponding parameters were 20% and 8.6% respectively. AUCs of the inferior, superior and temporal quadrant RNFL thickness parameters of SDOCT were also significantly (p<0.05 greater than the respective RNFL parameters of GDx ECC. LRs of outside normal limits category of SDOCT parameters ranged between 3.3 and 4.0 while the same of GDx ECC parameters ranged between 1.2 and 2.1. LRs of within normal limits category of SDOCT parameters ranged between 0.4 and 0.7 while the same of GDx ECC parameters ranged between 0.7 and 1.0.Abilities of the RNFL parameters of SDOCT and GDx ECC to diagnose preperimetric glaucoma were only moderate. Diagnostic abilities of the RNFL parameters of SDOCT were significantly better than that of GDx ECC in preperimetric glaucoma.

  1. Prevalence of early childhood caries among very young urban Boston children compared with US children.

    Science.gov (United States)

    Nunn, Martha E; Dietrich, Thomas; Singh, Harpreet K; Henshaw, Michelle M; Kressin, Nancy R

    2009-01-01

    The aims of this study were to compare prevalence of early childhood caries (ECC) in 1- to 3-year-old children seeing primary-care pediatricians at two urban medical centers in Boston to the prevalence of ECC in similarly aged US children surveyed as part of the Third National Health and Nutrition Examination Survey (NHANES III) and to assess risk factors for ECC among this cohort of children compared with risk factors among similarly aged US children. Characteristics of 787 1- to 3-year-old children from two urban Boston medical centers were compared with those of 3,644 similarly aged US children surveyed as part of NHANES III. Demographic and social characteristics and ECC prevalence by putative risk factors were compared. A multiple logistic regression model was fit to assess putative risk factors and difference between groups simultaneously. Race, age, previous dental visit, parents' education, and household income were significantly associated with ECC prevalence. Parents' place of birth was a significant effect modifier with lower ECC among Boston children of immigrants than among US children of immigrants. Lower ECC prevalence among urban Boston children of immigrant parents compared with US children of immigrant parents may reflect changing immigrant composition in the United States since NHANES III or a different immigrant composition in the Boston area compared with the United States. This finding reinforces the need for further research of immigrants in order to understand cultural practices that may affect oral health. Finally, low ECC prevalence among very young children reinforces the importance of early intervention in reducing ECC.

  2. Influence of social environment on caries prevalence in early childhood

    Directory of Open Access Journals (Sweden)

    Tušek Ivan

    2011-01-01

    Full Text Available Introduction. Early childhood caries (ECC is a special form of caries that affects decideous teeth with rapid progression and numerous complications. Objective. The aim of the study was to define the prevalence of ECC in children of the South Bačka area, the importance of social environment for the prevalence and severity of ECC, and define the model for its prevention. Methods. The survey was the cross-sectional analytical study in the 10% sample of children, aged 13-64 months, different sex, social status and human environment. Severity and prevalence of ECC were assessed by dental check-ups. The epidemiological data were obtained by the interview of parents. The tests of significant statistical differences were performed by the analysis variance and χ2 (p<0.05 test, as well as interdependence of ECC and single characteristics that could be a predictor of the disease by the logistic regression. Results. The prevalence of ECC was 30.5%. The highest disease frequency was found in children of male sex (35.1%, out of kindergardens (54.2%, in the third and the next born child in the family (46.9% and in part-time employed mothers (47.2% who had only elementary education (59.3% and were poorly informed about oral health. The highest prevalence (47.1% of ECC was found in children whose parents had the lowest income per month. Type 1 of ECC was the most presented one (75.0%. Conclusion. The higher prevalence and more severe ECC were found in the third and the next born male child from rural environment.

  3. Comparison of oxygen consumption in rats during uphill (concentric) and downhill (eccentric) treadmill exercise tests.

    Science.gov (United States)

    Chavanelle, Vivien; Sirvent, Pascal; Ennequin, Gaël; Caillaud, Kévin; Montaurier, Christophe; Morio, Béatrice; Boisseau, Nathalie; Richard, Ruddy

    2014-09-01

    The study of the physiological adaptations of skeletal muscle in response to eccentric (ECC) contraction is based on protocols in which exercise intensities are determined relative to the concentric (CON) reference exercise (as percentage of the CON maximal oxygen consumption, or VO2max). In order to use similar exercise protocols in rats, we compared the VO2 values during uphill (CON) and downhill (ECC) running tests. VO2 was measured in 15 Wistar rats during incremental treadmill running exercises with different slopes: level (0%), positive (+15% incline: CON+15%) and negative (i15% incline: ECC-15%; and 130% incline: ECC-30%). Similar VO2 values were obtained in the ECC-30% and CON+15% running conditions at the three target speeds (15, 25 and 35 cm/sec). Conversely, VO2 values were lower (p < 0.05) in the ECC-15% than in the CON+15% condition (CON+15% VO2/ECC-15% VO2 ratios ranging from 1.86 to 2.05 at the three target speeds). Thus, doubling the downhill slope gradient in ECC condition leads to an oxygen consumption level that is not significantly different as in CON condition. These findings can be useful for designing animal research protocols to study the effects of ECC and CON exercise in ageing population or subjects suffering from cardiovascular diseases. Key PointsVO2 in rats during treadmill race in eccentric and concentric conditions were measured.A novel breath-by-breath device allowing direct access to the animal was used.THREE DIFFERENT SLOPES: +15%, -15% and -30% were used.VO2 values obtained in the -30% eccentric and the +15% concentric conditions were not significantly different.

  4. Surgical techniques of cataract surgery and subsequent postoperative endophthalmitis.

    Science.gov (United States)

    Trinavarat, Adisak; Atchaneeyasakul, La-ongsri

    2005-11-01

    To compare the incidence and characteristics of patients with endophthalmitis after extracapsular cataract extraction (ECCE) to those after phacoemulsification Records of patients receiving intravitreal antibiotic injection to treat endophthalmitis after cataract surgery between Jan 2001 and Dec 2004 were reviewed. Demographic data and other characteristics including associated diseases, details of cataract surgical procedure and intraoperative complication, onset of endophthalmitis after cataract surgery, presenting symptoms and signs of endophthalmitis, how endophthalmitis was managed, causative organisms, duration of hospitalization and results of treatment were collected. This information was compared between those of endophthalmitis patients after ECCE and those after phacoemulsification. There were 5 cases who developed endophthalmitis after ECCE and 31 cases after phacoemulsification. The incidence was 0.365% after ECCE and 0.279% after phacoemulsification (p = 0.589). Visual acuity (VA) before cataract surgery in ECCE group was worse than the phacoemulsification group (median VA: counting fingers vs 6/36, p = 0.001). Median onset of endophthalmitis was 8 days after ECCE and 6 days after phacoemulsification. Presenting symptoms and signs were similar. Causative agents were identified in 4 (80%) and 14 (45%) cases in the ECCE and phacoemulsification groups respectively. Gram-positive bacteria were the major cause of infection in both groups. Endophthalmitis caused by citrobacter sp. in ECCE group and enterococcus or streptococcus sps. the phacoemulsification in the group ended up with enucleation or no light perception. The present study has not demonstrated an apparent difference between endophthalmitis after ECCE and those after phacoemulsification. Endophthalmitis after either procedure can be managed as the same condition.

  5. Peripapillary retinal nerve fiber layer assessment of spectral domain optical coherence tomography and scanning laser polarimetry to diagnose preperimetric glaucoma.

    Science.gov (United States)

    Rao, Harsha L; Yadav, Ravi K; Addepalli, Uday K; Chaudhary, Shashikant; Senthil, Sirisha; Choudhari, Nikhil S; Garudadri, Chandra S

    2014-01-01

    To compare the abilities of peripapillary retinal nerve fiber layer (RNFL) parameters of spectral domain optical coherence tomograph (SDOCT) and scanning laser polarimeter (GDx enhanced corneal compensation; ECC) in detecting preperimetric glaucoma. In a cross-sectional study, 35 preperimetric glaucoma eyes (32 subjects) and 94 control eyes (74 subjects) underwent digital optic disc photography and RNFL imaging with SDOCT and GDx ECC. Ability of RNFL parameters of SDOCT and GDx ECC to discriminate preperimetric glaucoma eyes from control eyes was compared using area under receiver operating characteristic curves (AUC), sensitivities at fixed specificities and likelihood ratios (LR). AUC of the global average RNFL thickness of SDOCT (0.786) was significantly greater (p<0.001) than that of GDx ECC (0.627). Sensitivities at 95% specificity of the corresponding parameters were 20% and 8.6% respectively. AUCs of the inferior, superior and temporal quadrant RNFL thickness parameters of SDOCT were also significantly (p<0.05) greater than the respective RNFL parameters of GDx ECC. LRs of outside normal limits category of SDOCT parameters ranged between 3.3 and 4.0 while the same of GDx ECC parameters ranged between 1.2 and 2.1. LRs of within normal limits category of SDOCT parameters ranged between 0.4 and 0.7 while the same of GDx ECC parameters ranged between 0.7 and 1.0. Abilities of the RNFL parameters of SDOCT and GDx ECC to diagnose preperimetric glaucoma were only moderate. Diagnostic abilities of the RNFL parameters of SDOCT were significantly better than that of GDx ECC in preperimetric glaucoma.

  6. Impact of physical fitness and biometric data on the quality of external chest compression: a randomised, crossover trial

    Directory of Open Access Journals (Sweden)

    Russo Sebastian G

    2011-11-01

    Full Text Available Abstract Background During circulatory arrest, effective external chest compression (ECC is a key element for patient survival. In 2005, international emergency medical organisations changed their recommended compression-ventilation ratio (CVR from 15:2 to 30:2 to acknowledge the vital importance of ECC. We hypothesised that physical fitness, biometric data and gender can influence the quality of ECC. Furthermore, we aimed to determine objective parameters of physical fitness that can reliably predict the quality of ECC. Methods The physical fitness of 30 male and 10 female healthcare professionals was assessed by cycling and rowing ergometry (focussing on lower and upper body, respectively. During ergometry, continuous breath-by-breath ergospirometric measurements and heart rate (HR were recorded. All participants performed two nine-minute sequences of ECC on a manikin using CVRs of 30:2 and 15:2. We measured the compression and decompression depths, compression rates and assessed the participants' perception of exhaustion and comfort. The median body mass index (BMI; male 25.4 kg/m2 and female 20.4 kg/m2 was used as the threshold for subgroup analyses of participants with higher and lower BMI. Results HR during rowing ergometry at 75 watts (HR75 correlated best with the quality of ECC (r = -0.57, p 75, the compression depth decreased over time, beginning after four minutes for the 15:2 CVR and after three minutes for the 30:2 CVR. Although found to be more exhausting, a CVR of 30:2 was rated as being more comfortable. Conclusion The quality of the ECC and fatigue can both be predicted by BMI and physical fitness. An evaluation focussing on the upper body may be a more valid predictor of ECC quality than cycling based tests. Our data strongly support the recommendation to relieve ECC providers after two minutes.

  7. Progress in Early Childhood Caries and Opportunities in Research, Policy, and Clinical Management

    DEFF Research Database (Denmark)

    Garcia, Raul; Borrelli, Belinda; Dhar, Vineet

    2015-01-01

    to identify preschool children at risk for caries. Fluoridated toothpaste and fluoride varnish currently are the most effective chemotherapeutic strategies to prevent ECC. Motivational interviewing, a form of patient-centered counseling, is effective for motivating oral health behaviors and shows promise...... for reducing caries. Additionally, evidence is emerging that shows the value of chronic disease management approaches and integrating ECC oral health care within medical care settings. Recommendations for future directions in ECC research and policy were also key outcomes of the conference....

  8. The effectiveness of the biannual application of silver nitrate solution followed by sodium fluoride varnish in arresting early childhood caries in preschool children: study protocol for a randomised controlled trial

    OpenAIRE

    Chu, Chun-Hung; Gao, Sherry Shiqian; Li, Samantha KY; Wong, May CM; Lo, Edward CM

    2015-01-01

    Background The application of 38 % silver diamine fluoride (SDF) has been shown to be effective in arresting early childhood caries (ECC). Since SDF is not available in certain countries, some dentists use adjunctive application of 25 % silver nitrate (AgNO3) and 5 % sodium fluoride (NaF) to arrest ECC. This randomised controlled trial will systematically compare the efficacy of a 25 % AgNO3 solution followed by 5 % NaF varnish with that of a 38 % SDF solution in arresting ECC when applied at...

  9. 3rd Euro-China Conference on Intelligent Data Analysis and Applications

    CERN Document Server

    Snášel, Václav; Sung, Tien-Wen; Wang, Xiao

    2017-01-01

    This book gathers papers presented at the ECC 2016, the Third Euro-China Conference on Intelligent Data Analysis and Applications, which was held in Fuzhou City, China from November 7 to 9, 2016. The aim of the ECC is to provide an internationally respected forum for scientific research in the broad areas of intelligent data analysis, computational intelligence, signal processing, and all associated applications of artificial intelligence (AI). The third installment of the ECC was jointly organized by Fujian University of Technology, China, and VSB-Technical University of Ostrava, Czech Republic. The conference was co-sponsored by Taiwan Association for Web Intelligence Consortium, and Immersion Co., Ltd.

  10. Development of Flexible Link Slabs using Ductile Fiber Reinforced Concrete

    DEFF Research Database (Denmark)

    Lárusson, Lárus Helgi

    emphasis oncrack formation and development at the rebar-matrix interface during direct tensile loading. Utilizing a high definition DIC technique in a novel approach, detailed measurements of the crack formation and debonding process are obtained. It is found that ductile ECC, in contrast to conventional...... two adjacent bridge deck segments. The link slab element, composed of GFRP reinforced ECC,exhibited the same tension stiffening and tension strengthening behavior with limited crack widths as was observed in the reinforced prisms under monotonic and cyclic loading. The combination of ductile ECC...

  11. The effectiveness of the biannual application of silver nitrate solution followed by sodium fluoride varnish in arresting early childhood caries in preschool children: study protocol for a randomised controlled trial

    OpenAIRE

    Chu, Chun-Hung; Gao, Sherry Shiqian; Li, Samantha KY; Wong, May CM; Lo, Edward CM.

    2015-01-01

    Background The application of 38 % silver diamine fluoride (SDF) has been shown to be effective in arresting early childhood caries (ECC). Since SDF is not available in certain countries, some dentists use adjunctive application of 25 % silver nitrate (AgNO3) and 5 % sodium fluoride (NaF) to arrest ECC. This randomised controlled trial will systematically compare the efficacy of a 25 % AgNO3 solution followed by 5 % NaF varnish with that of a 38 % SDF solution in arresting ECC when applied at...

  12. Micellar catalysis in the retro-Knoevenagel reaction of ethyl--cyanocinnamates

    Indian Academy of Sciences (India)

    K Rajasekaran; A Sarathi; S Ramalakshmi

    2008-09-01

    Kinetics of base catalysed hydrolytic cleavage of ethyl -cyanocinnamate (ECC) and several para-substituted ECC have been investigated spectrophotometrically in the presence of anionic surfactant sodium laurylsulphate (NaLS). The rate of cleavage of ECC was retarded by NaLS. The pseudo-first order rate constants, obs, correlate with the Hammett $\\sigma^{+}_{p}$ - constants. The ρ+ value (0.86) in aqueous medium is less than ρ+ value (1.11) in 0.02 M NaLS. Kinetic data were analysed by Menger-Portnoy and Piszkiwicz model. The substrate-micelle binding constants, , correlate with the Hammett -constants and Hansch hydrophobicity constants - of the substituents.

  13. Systematic study of complete fusion suppression in reactions involving weakly bound nuclei at energies above the Coulomb barrier

    CERN Document Server

    Wang, Bing; Diaz-Torres, Alexis; Zhao, En-Guang; Zhou, Shan-Gui

    2016-01-01

    Complete fusion excitation functions of reactions involving breakup are studied by using the empirical coupled-channel (ECC) model with breakup effects considered. An exponential function with two parameters is adopted to describe the prompt-breakup probability in the ECC model. These two parameters are fixed by fitting the measured prompt-breakup probability or the complete fusion cross sections. The suppression of complete fusion at energies above the Coulomb barrier is studied by comparing the data with the predictions from the ECC model without the breakup channel considered. The results show that the suppression of complete fusion are roughly independent of the target for the reactions involving the same projectile.

  14. China QIUSHI SEEKING TRUTH no 3, 1 August 1988

    Science.gov (United States)

    1988-09-16

    in the style of the "Old Testament," "Twighlight of the Idols" (1888), "The Antichrist" (1888) and " Ecce Homo ." (1888). In addi- tion, after...values: That is my formula for mankind’s highest activity of self-affirma- tion. For me, this formula has become concrete life" (" Ecce Homo "). These...term, Christian morality." (" Ecce Homo ") Nietzsche held that "the second denial is more decisive." The summation of this second denial was the

  15. An atypical case of successful resuscitation of an accidental profound hypothermia patient, occurring in a temperate climate.

    LENUS (Irish Health Repository)

    Coleman, E

    2010-03-01

    Cases of accidental profound hypothermia occur most frequently in cold, northern climates. We describe an atypical case, occurring in a temperate climate, where a hypothermic cardiac-arrested patient was successfully resuscitated using extracorporeal circulation (ECC).

  16. Early Childhood Caries

    Directory of Open Access Journals (Sweden)

    Yumiko Kawashita

    2011-01-01

    Full Text Available Dental caries is one of the most common childhood diseases, and people continue to be susceptible to it throughout their lives. Although dental caries can be arrested and potentially even reversed in its early stages, it is often not self-limiting and progresses without proper care until the tooth is destroyed. Early childhood caries (ECC is often complicated by inappropriate feeding practices and heavy infection with mutans streptococci. Such children should be targeted with a professional preventive program that includes oral hygiene instructions for mothers or caregivers, along with fluoride and diet counseling. However, these strategies alone are not sufficient to prevent dental caries in high-risk children; prevention of ECC also requires addressing the socioeconomic factors that face many families in which ECC is endemic. The aim of this paper is to systematically review information about ECC and to describe why many children are suffering from dental caries.

  17. Characterising and modelling extended conducted electromagnetic emission

    CSIR Research Space (South Africa)

    Grobler, Inus

    2013-06-01

    Full Text Available -1 2013 IEEE Energy Conversion Congress and Exposition Asia (ECCE Downunder), Melbourne, Australia, 3-6 June 2013 Characterising and Modelling Extended Conducted Electromagnetic Emission I Grobler1 and MN Gitau2 Department of Electrical...

  18. Importance of eccentric actions in performance adaptations to resistance training

    Science.gov (United States)

    Dudley, Gary A.; Miller, Bruce J.; Buchanan, Paul; Tesch, Per A.

    1991-01-01

    The importance of eccentric (ecc) muscle actions in resistance training for the maintenance of muscle strength and mass in hypogravity was investigated in experiments in which human subjects, divided into three groups, were asked to perform four-five sets of 6 to 12 repetitions (rep) per set of three leg press and leg extension exercises, 2 days each weeks for 19 weeks. One group, labeled 'con', performed each rep with only concentric (con) actions, while group con/ecc with performed each rep with only ecc actions; the third group, con/con, performed twice as many sets with only con actions. Control subjects did not train. It was found that resistance training wih both con and ecc actions induced greater increases in muscle strength than did training with only con actions.

  19. Influence of eccentric actions on the metabolic cost of resistance exercise

    Science.gov (United States)

    Dudley, Gary A.; Golden, Catherine L.; Tesch, Per A.; Harris, Robert T.; Buchanan, Paul

    1991-01-01

    The contributions of concentric (con) and eccentric (ecc) muscle actions are evaluated with respect to increasing the metabolic cost of resistance exercise. Male subjects perform leg exercise with either con and ecc actions or only con actions while the net energy cost of the exercise is measured by oxygen consumption data. In both groups, the con actions require 290 J/kg body weight of total work, with an energy cost of 0.003 cal/J. The energy costs for the con/ecc actions of the second group is increased by 14 percent. The metabolic cost of leg exercise is concluded to be primarily generated by the con leg actions, and ecc leg actions increase the resistance with only a slight increase in required energy. The findings are significant for practical applications that emphasize the conservation of energy expenditure during exercise in spacecraft environments.

  20. Strengthening masonry infill panels using engineered cementitious composites

    DEFF Research Database (Denmark)

    Dehghani, Ayoub; Fischer, Gregor; Nateghi Alahi, Fariborz

    2015-01-01

    This comprehensive experimental study aims at investigating the behavior of masonry infill panels strengthened by fiber reinforced engineered cementitious composites (ECC). The experimental program included testing of materials, masonry elements and panels. Material tests were carried out first f...

  1. Risk factors of HIV-related oral lesions in adults

    National Research Council Canada - National Science Library

    Petruzzi, Maria Noel Marzano Rodrigues; Cherubini, Karen; Salum, Fernanda Gonçalves; Figueiredo, Maria Antonia Zancanaro De

    2013-01-01

    .... Using a standardized form, socio-demographic and clinical data were recorded. Exclusively and definitively diagnosed oral pathologies were included and classified according to ECC criteria on Oral Problems Related to HIV Infection...

  2. Risk factors of HIV-related oral lesions in adults Factores de riesgo de lesiones bucales asociadas al VIH en adultos Fatores de risco de lesões bucais associadas ao HIV em adultos

    National Research Council Canada - National Science Library

    Maria Noel Marzano Rodrigues Petruzzi; Karen Cherubini; Fernanda Gonçalves Salum; Maria Antonia Zancanaro De Figueiredo

    2013-01-01

    .... Using a standardized form, socio-demographic and clinical data were recorded. Exclusively and definitively diagnosed oral pathologies were included and classified according to ECC criteria on Oral Problems Related to HIV Infection...

  3. Influence of eccentric actions on the metabolic cost of resistance exercise

    Science.gov (United States)

    Dudley, Gary A.; Golden, Catherine L.; Tesch, Per A.; Harris, Robert T.; Buchanan, Paul

    1991-01-01

    The contributions of concentric (con) and eccentric (ecc) muscle actions are evaluated with respect to increasing the metabolic cost of resistance exercise. Male subjects perform leg exercise with either con and ecc actions or only con actions while the net energy cost of the exercise is measured by oxygen consumption data. In both groups, the con actions require 290 J/kg body weight of total work, with an energy cost of 0.003 cal/J. The energy costs for the con/ecc actions of the second group is increased by 14 percent. The metabolic cost of leg exercise is concluded to be primarily generated by the con leg actions, and ecc leg actions increase the resistance with only a slight increase in required energy. The findings are significant for practical applications that emphasize the conservation of energy expenditure during exercise in spacecraft environments.

  4. Kuidas anda oma elule mõte? Milli ja Nietzsche eksperiment / Märt Väljataga

    Index Scriptorium Estoniae

    Väljataga, Märt, 1965-

    1996-01-01

    Arvustus: Mill, John Stuart. Vabadusest / Tlk. Kaja Tael. Tln. : Hortus Litterarum, 1996. (Avatud Eesti Raamat); Nietzsche, Friedrich. Ecce homo : Kuidas saadakse selleks, mis ollakse / Tlk. Jaan Undusk. Tln. : Vagabund, 1996. (Avatud Eesti Raamat)

  5. InterProScan Result: FS826625 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS826625 FS826625_6_ORF1 ECC063214CAB06EE PANTHER PTHR10513 DEOXYNUCLEOSIDE KINASE ...FAMILY PROTEIN 4.3e-49 T IPR002624 Deoxynucleoside kinase Molecular Function: ATP binding (GO:0005524) ...

  6. AFLP Phylogeny of 36 Erythroxylum species- genetic relationships among Erythroxylum species inferred by AFLP analysis

    Science.gov (United States)

    The plant genus Erythroxylum is known for four cultivated taxa, Erythroxylum coca var. coca (Ecc), Erythroxylum coca var. ipadu (Eci), Erythroxylum novogranatense var. novogranatense (Enn) and Erythroxylum novogranatense var. truxillense (Ent) that are cultivated primarily for the illicit extraction...

  7. Exercise Based- Pain Relief Program

    DEFF Research Database (Denmark)

    Zadeh, Mahdi Hossein

    in the current study was to use exercise induced- muscle damage followed by ECC as an acute pain model and observe its effects on the sensitivity of the nociceptive system and blood supply in healthy subjects. Then, the effect of a repeated bout of the same exercise as a healthy pain relief strategy......Exercise-based pain management programs are suggested for relieving from musculoskeletal pain; however the pain experienced after unaccustomed, especially eccentric exercise (ECC) alters people´s ability to participate in therapeutic exercises. Subsequent muscle pain after ECC has been shown...... to cause localized pressure pain and hyperalgesia. A prior bout of ECC has been repeatedly reported to produce a protective adaptation known as repeated bout effect (RBE). One of the main scopes of the current project was to investigate the adaptations by which the RBE can be resulted from. The approach...

  8. Short communication: polymicrobial community in teeth associated with severe early-childhood caries.

    Science.gov (United States)

    de Paula, V A; Ferreira, D C; Carmo, F L; Rosardio, A S; Dos Santos, K R; Maia, L C; Primo, L G

    2011-10-01

    This was to characterise the microbial diversity in the complex dental plaque of children with severe early-childhood caries (S-ECC), using the denaturing gel gradient electrophoresis (DGGE) technique. The DGGE technique was used as a diagnostic tool to analyse samples from the oral cavity of a patient with S-ECC. Dental plaque samples from a 3-year-old child with S-ECC were taken from the primary central maxillary incisor (biofilm on vestibular surface), primary maxillary molar (biofilm on vestibular surface), primary central maxillary incisor (dentine), primary maxillary molar (dentine) and saliva and then analysed by PCR-DGGE. Three bands occurred in all samples, moreover, 86% of similarity was observed in the pattern of bands between incisor and molar teeth biofilm samples, including four similar bands. DGGE is a valuable tool for differentiating the microbial composition of the oral plaque in S-ECC children.

  9. Social and Behavioral Determinants for Early Childhood Caries among Preschool Children in India.

    Science.gov (United States)

    Jain, Mitali; Namdev, Ritu; Bodh, Meenakshi; Dutta, Samir; Singhal, Parul; Kumar, Arun

    2015-01-01

    Background and aims. Early Childhood Caries (ECC) is a public health problem with biological, social and behavioural determinants and the notion that the principal etiology is inappropriate feeding modalities is no longer tenable. Hence this study was undertaken to assess the relationship between ECC and socio-demographic factors, dietary habits, oral hygiene habits and parental characteristics. Materials and methods. The study involved a dental examination of 1400 children aged 0-71 months, recording caries using Gruebbel's deft index and a structured questionnaire to interview parents or caretakers. The tabulated data was statistically analyzed using t-test and ANOVA at 5% level of significance. Results. The variables significantly associated with ECC were age (P0.05). Conclusion. ECC is preventable and manageable with proper information and skills. It is important for healthcare professionals, family physicians and parents to be cognizant of the involved risk factors as their preventive efforts represent the first line of defense.

  10. DNA-Cryptography-Based Obfuscated Systolic Finite Field Multiplier for Secure Cryptosystem in Smart Grid

    Science.gov (United States)

    Chen, Shaobo; Chen, Pingxiuqi; Shao, Qiliang; Basha Shaik, Nazeem; Xie, Jiafeng

    2017-05-01

    The elliptic curve cryptography (ECC) provides much stronger security per bits compared to the traditional cryptosystem, and hence it is an ideal role in secure communication in smart grid. On the other side, secure implementation of finite field multiplication over GF(2 m ) is considered as the bottle neck of ECC. In this paper, we present a novel obfuscation strategy for secure implementation of systolic field multiplier for ECC in smart grid. First, for the first time, we propose a novel obfuscation technique to derive a novel obfuscated systolic finite field multiplier for ECC implementation. Then, we employ the DNA cryptography coding strategy to obfuscate the field multiplier further. Finally, we obtain the area-time-power complexity of the proposed field multiplier to confirm the efficiency of the proposed design. The proposed design is highly obfuscated with low overhead, suitable for secure cryptosystem in smart grid.

  11. Fast Distributed Computation of Distances in Networks

    CERN Document Server

    Almeida, Paulo Sérgio; Cunha, Alcino

    2011-01-01

    This paper presents a distributed algorithm to simultaneously compute the diameter, radius and node eccentricity in all nodes of a synchronous network. Such topological information may be useful as input to configure other algorithms. Previous approaches have been modular, progressing in sequential phases using building blocks such as BFS tree construction, thus incurring longer executions than strictly required. We present an algorithm that, by timely propagation of available estimations, achieves a faster convergence to the correct values. We show local criteria for detecting convergence in each node. The algorithm avoids the creation of BFS trees and simply manipulates sets of node ids and hop counts. For the worst scenario of variable start times, each node i with eccentricity ecc(i) can compute: the node eccentricity in diam(G)+ecc(i)+2 rounds; the diameter in 2*diam(G)+ecc(i)+2 rounds; and the radius in diam(G)+ecc(i)+2*radius(G) rounds.

  12. The incidence of ptosis following extracapsular and phacoemulsification surgery: comparison of two prospective studies and review of the literature.

    Science.gov (United States)

    Puvanachandra, Narman; Hustler, Adam; Seah, Lay Leng; Tyers, Anthony G

    2010-12-01

    We prospectively compared 120 patients who underwent either phacoemulsification or extracapsular cataract (ECCE) surgery to establish the incidence of postoperative ptosis between the two techniques. Of the 120 patients, 60 underwent ECCE (unpublished data 1989) and 60 had phacoemulsification. Data was collected prospectively on upper and lower margin reflex distance, upper lid skin crease and levator function, preoperatively and 6 weeks postoperatively. Photographs were taken pre and postoperatively and examined by a blinded observer. At 6 weeks, ptosis was present in 18% of ECCE patients compared with 0% in the phacoemulsification group. By changing from ECCE to phacoemulsification the incidence of postoperative ptosis has reduced. The possibility to induce postoperative ptosis remains, potential mechanisms are discussed.

  13. Mees, naine ja Pulleritsu hirmud / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    1999-01-01

    Aktinäitus "Mees ja naine: mees & naine" ning Elisabeth Ohlsoni fotonäitus 'Ecce homo' Pärnu Uue Kunsti Muuseumis. E. Ohlsoni fotolavastustes Kristuse elust kehastavad tegelasi seksuaalvähemuste esindajad.

  14. Die Via Dolorosa

    Directory of Open Access Journals (Sweden)

    W. J. van der Merwe

    1957-03-01

    Full Text Available In die hartjie van Jerusalem, die heilige stad vir Jood, Mohammedaan en Christen staan daar ’n boog, die ,,Ecce Homoboog” genaamd, en 'n klein endjie daarvandaan, die Heilige Grafkerk.

  15. Robustness of Watermarking: Is Error Correcting Coding Effective?%水印鲁棒性:纠错编码有效吗?

    Institute of Scientific and Technical Information of China (English)

    黄继武; 谷利民; 施云庆

    2005-01-01

    Robustness is one of the most important requirements of digital watermarking for many applications. Spread-spectrum based methods are not effective enough to ensure their robustness. By modeling digital watermarking as digital communications, several researchers proposed using error correcting coding (ECC) to improve robustness. However, an important fact that has long been neglected is that due to the imperceptibility requirement, the redundancy introduced by ECC will lead to a decrease of the magnitude of watermark signal. Therefore, a problem arises naturally:Could the usage of ECC effectively improve the robustness of watermarking? This paper addresses this problem from the perspectives of both theoretical analysis and experimental investigation. Our investigation shows that ECG cannot effectively improve the robustness of watermarking against a great majority of various attacks except for cropping and jitter attacks. Hence, ECC should not be considered as a universal measure that can be employed to enhance robustness of watermarking.

  16. Interaction between Engineered Cementitious Composites Lining and Foundation Subsurface Drain

    Directory of Open Access Journals (Sweden)

    Cleopatra Panganayi

    2011-01-01

    Full Text Available The effect of cyclic loads on the surface profiles of ECC linings cast on foundations comprising crushed stone and compacted soil was investigated. A geotextile was embedded between the crushed stone and ECC lining for some of the samples. After 28 days of water curing, the hardened surfaces were loaded and monitored for roughness and crack development by measuring surface levels and crack widths, respectively. Neither cracking nor significant variations in the lateral profiles were observed on all the samples for all the loads applied. However, significant variations which depended on the foundation types were observed in the vertical profiles. It was concluded that while ECC can resist cracking due to its high strain capacity, its flexibility causes ECC linings to assume the shape of the foundation material, which can increase the surface roughness at certain loading configurations.

  17. Prediction of Early Childhood Caries via Spatial-Temporal Variations of Oral Microbiota.

    Science.gov (United States)

    Teng, Fei; Yang, Fang; Huang, Shi; Bo, Cunpei; Xu, Zhenjiang Zech; Amir, Amnon; Knight, Rob; Ling, Junqi; Xu, Jian

    2015-09-09

    Microbiota-based prediction of chronic infections is promising yet not well established. Early childhood caries (ECC) is the most common infection in children. Here we simultaneously tracked microbiota development at plaque and saliva in 50 4-year-old preschoolers for 2 years; children either stayed healthy, transitioned into cariogenesis, or experienced caries exacerbation. Caries onset delayed microbiota development, which is otherwise correlated with aging in healthy children. Both plaque and saliva microbiota are more correlated with changes in ECC severity (dmfs) during onset than progression. By distinguishing between aging- and disease-associated taxa and exploiting the distinct microbiota dynamics between onset and progression, we developed a model, Microbial Indicators of Caries, to diagnose ECC from healthy samples with 70% accuracy and predict, with 81% accuracy, future ECC onsets for samples clinically perceived as healthy. Thus, caries onset in apparently healthy teeth can be predicted using microbiota, when appropriately de-trended for age.

  18. Kuidas anda oma elule mõte? Milli ja Nietzsche eksperiment / Märt Väljataga

    Index Scriptorium Estoniae

    Väljataga, Märt, 1965-

    1996-01-01

    Arvustus: Mill, John Stuart. Vabadusest / Tlk. Kaja Tael. Tln. : Hortus Litterarum, 1996. (Avatud Eesti Raamat); Nietzsche, Friedrich. Ecce homo : Kuidas saadakse selleks, mis ollakse / Tlk. Jaan Undusk. Tln. : Vagabund, 1996. (Avatud Eesti Raamat)

  19. Mees, naine ja Pulleritsu hirmud / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    1999-01-01

    Aktinäitus "Mees ja naine: mees & naine" ning Elisabeth Ohlsoni fotonäitus 'Ecce homo' Pärnu Uue Kunsti Muuseumis. E. Ohlsoni fotolavastustes Kristuse elust kehastavad tegelasi seksuaalvähemuste esindajad.

  20. Subbanding, Charge Transport and Related Applications in Semiconductor Devices.

    Science.gov (United States)

    1977-10-01

    These devices use a p-n homo -junction to confine the free electronic charge in the semiconductor to conducting regions so narrow as to exhibit...27.172 Table 6A ~0 ENERGY IN MILLI-ELECTRON VOLTS WC IN ANGSTROMS WC EC(6) ECC 7) EC(8) EC(9) ECC 10) 1.2 3669047 432.986 499.951 566.937 633.941 1.5...VC IN ANGSTROMS (6 ECC ) ECC7) EC(s) EC(9) ECCIS) 3t 236.132 279.167 322.269 365.257 418.319 1,’ 235;907 275;922 321� 364;976 408.013 I. 235,;635

  1. Combined blockade of ADP receptors and PI3-kinase p110β fully prevents platelet and leukocyte activation during hypothermic extracorporeal circulation.

    Directory of Open Access Journals (Sweden)

    Stefanie Krajewski

    Full Text Available Extracorporeal circulation (ECC and hypothermia are used to maintain stable circulatory parameters and improve the ischemia tolerance of patients in cardiac surgery. However, ECC and hypothermia induce activation mechanisms in platelets and leukocytes, which are mediated by the platelet agonist ADP and the phosphoinositide-3-kinase (PI3K p110β. Under clinical conditions these processes are associated with life-threatening complications including thromboembolism and inflammation. This study analyzes effects of ADP receptor P(2Y(12 and P(2Y(1 blockade and PI3K p110β inhibition on platelets and granulocytes during hypothermic ECC. Human blood was treated with the P(2Y(12 antagonist 2-MeSAMP, the P(2Y(1 antagonist MRS2179, the PI3K p110β inhibitor TGX-221, combinations thereof, or PBS and propylene glycol (controls. Under static in vitro conditions a concentration-dependent effect regarding the inhibition of ADP-induced platelet activation was found using 2-MeSAMP or TGX-221. Further inhibition of ADP-mediated effects was achieved with MRS2179. Next, blood was circulated in an ex vivo ECC model at 28°C for 30 minutes and various platelet and granulocyte markers were investigated using flow cytometry, ELISA and platelet count analysis. GPIIb/IIIa activation induced by hypothermic ECC was inhibited using TGX-221 alone or in combination with P(2Y blockers (p<0.05, while no effect of hypothermic ECC or antiplatelet agents on GPIIb/IIIa and GPIbα expression and von Willebrand factor binding was observed. Sole P(2Y and PI3K blockade or a combination thereof inhibited P-selectin expression on platelets and platelet-derived microparticles during hypothermic ECC (p<0.05. P(2Y blockade alone or combined with TGX-221 prevented ECC-induced platelet-granulocyte aggregate formation (p<0.05. Platelet adhesion to the ECC surface, platelet loss and Mac-1 expression on granulocytes were inhibited by combined P(2Y and PI3K blockade (p<0.05. Combined blockade of P

  2. Association Between Nocturnal Breastfeeding and Snacking Habits and the Risk of Early Childhood Caries in 18- to 23-Month-Old Japanese Children

    OpenAIRE

    ,

    2015-01-01

    Background Early childhood caries (ECC) is one of the most prevalent chronic diseases among children. The aim of this cross-sectional study was to investigate the association between nocturnal breastfeeding, snacking habits, or other risk factors and ECC in 18- to 23-month-old Japanese children. Methods Study subjects were 1675 children aged 18 to 23 months. A self-administered questionnaire was completed by parents or guardians of the children. The survey contents included such things as num...

  3. Reducing disease burden and health inequalities arising from chronic disease among Indigenous children: an early childhood caries intervention

    OpenAIRE

    Merrick Jessica; Chong Alwin; Parker Eleanor; Roberts-Thomson Kaye; Misan Gary; Spencer John; Broughton John; Lawrence Herenia; Jamieson Lisa

    2012-01-01

    Abstract Background This study seeks to determine if implementing a culturally-appropriate early childhood caries (ECC) intervention reduces dental disease burden and oral health inequalities among Indigenous children living in South Australia, Australia. Methods/Design This paper describes the study protocol for a randomised controlled trial conducted among Indigenous children living in South Australia with an anticipated sample of 400. The ECC intervention consists of four components: (1) p...

  4. Identification of Prostate Cancer-Specific microDNAs

    Science.gov (United States)

    2016-02-01

    reviewing instructions, searching existing data sources, gathering and maintaining the data needed, and completing and reviewing this collection of...extrachromosomal circular DNAs (eccDNAs), called microDNAs. Unlike previously reported eccDNAs, microDNAs are relatively small in length, map to unique DNA...exonuclease than linear DNAs and can be stably present in the cells or even possibly in the circulating system. Therefore, overall goal of this application

  5. Effectiveness of narrow-band imaging magnification for invasion depth in early colorectal cancer

    Institute of Scientific and Technical Information of China (English)

    Masakatsu; Fukuzawa; Yutaka; Saito; Takahisa; Matsuda; Toshio; Uraoka; Takao; Itoi; Fuminori; Moriyasu

    2010-01-01

    AIM: To evaluate the surface microvascular patterns of early colorectal cancer (ECC) using narrow-band imaging (NBI) with magnification and its effectiveness for invasion depth diagnosis. METHODS: We studied 112 ECC lesions [mucosal/ submucosal superficial (m/sm-s), 69; sm-deep (sm-d), 43] ≥ 10 mm that subsequently underwent endoscopic or surgical treatment at our hospital. We compared microvascular architecture revealed by NBI with magnification to histological findings and then to magnifi- cation colonosc...

  6. In vitro characterization of electrochemically compacted collagen matrices for corneal applications.

    Science.gov (United States)

    Kishore, Vipuil; Iyer, Ranjani; Frandsen, Athela; Nguyen, Thuy-Uyen

    2016-10-06

    Loss of vision due to corneal disease is a significant problem worldwide. Transplantation of donor corneas is a viable treatment option but limitations such as short supply and immune-related complications call for alternative options for the treatment of corneal disease. A tissue engineering-based approach using a collagen scaffold is a promising alternative to develop a bioengineered cornea that mimics the functionality of native cornea. In this study, an electrochemical compaction method was employed to synthesize highly dense and transparent collagen matrices. We hypothesized that chemical crosslinking of electrochemically compacted collagen (ECC) matrices will maintain transparency, improve stability, and enhance the mechanical properties of the matrices to the level of native cornea. Further, we hypothesized that keratocyte cell viability and proliferation will be maintained on crosslinked ECC matrices. The results indicated that uncrosslinked and 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide-N-hydroxysuccinimide (EDC-NHS) crosslinked ECC matrices were highly transparent with light transmission measurements comparable to native cornea. Stability tests showed that while the uncrosslinked ECC matrices degraded within 6 h when treated with collagenase, EDC-NHS or genipin crosslinking significantly improved the stability of ECC matrices (192 h for EDC-NHS and 256 h for genipin). Results from the mechanical tests showed that both EDC-NHS and genipin crosslinking significantly improved the strength and modulus of ECC matrices. Cell culture studies showed that keratocyte cell viability and proliferation are maintained on EDC-NHS crosslinked ECC matrices. Overall, results from this study suggest that ECC matrices have the potential to be developed as a functional biomaterial for corneal repair and regeneration.

  7. Does degree of alteration in effort sense caused by eccentric exercise significantly affect initial exercise hyperpnea in humans?

    Science.gov (United States)

    Hotta, Norio; Yamamoto, Kaoru; Ogata, Hisayoshi; Maher, Patrick; Okumura, Naoya; Ishida, Koji

    2016-08-24

    Previous research has shown an exaggeration in exercise hyperpnea 2 days after eccentric exercise (ECC). Enhancement in central command has been suggested as one candidate to account for this effect given that ECC-induced neuromuscular dysfunction increases relative exercise intensity, thus resulting in reinforcement of effort sense. The purpose of this study was, therefore, to elucidate whether the degree of alteration in effort sense caused by ECC affects exercise hyperpnea. Ten subjects performed 20-s single-arm extension-flexion exercises with weight strapped to the wrist, and ventilatory response was measured before (Pre) and 2 days after ECC (D2). Relative exercise intensity at Pre was 5 % of maximal voluntary contraction (MVC) of Pre, whereas that at D2 was 9 % MVC of D2 because of decline in muscle strength. Ventilatory responses were significantly exaggerated at D2 with a significant increase in effort sense. Although effort sense was significantly reduced during exercise at D2 when wrist weight was subtracted to match relative exercise intensity at Pre (5 % MVC of D2), ventilatory responses were still significantly higher than those of Pre. After the disappearance of post-ECC muscle damage, subjects performed the same exercise with weight added (9 % MVC of Pre) so that effort was equalized to match that of D2; however, no significant increase in ventilatory response was detected. The fact that the extent of change in effort sense caused by ECC-induced neuromuscular dysfunction did not affect ventilatory response at the onset of exercise after ECC may suggest that the exaggeration of ventilatory response after ECC is caused by mechanisms other than alteration of the central command.

  8. Ischemic Preconditioning Blunts Muscle Damage Responses Induced by Eccentric Exercise.

    Science.gov (United States)

    Franz, Alexander; Behringer, Michael; Harmsen, Jan-Frieder; Mayer, Constantin; Krauspe, Rüdiger; Zilkens, Christoph; Schumann, Moritz

    2017-08-22

    Ischemic preconditioning (IPC) is known to reduce muscle damage induced by ischemia and reperfusion-injury (I/R-Injury) during surgery. Due to similarities between the pathophysiological formation of I/R-injury and eccentric exercise-induced muscle damage (EIMD), as characterized by an intracellular accumulation of Ca, an increased production of reactive oxygen species and increased pro-inflammatory signaling, the purpose of the present study was to investigate whether IPC performed prior to eccentric exercise may also protect against EIMD. Nineteen healthy men were matched to an eccentric only (ECC) (n=9) or eccentric proceeded by IPC group (IPC+ECC) (n=10). The exercise protocol consisted of bilateral biceps curls (3x10 repetitions at 80% of the concentric 1RM). In IPC+ECC, IPC was applied bilaterally at the upper arms by a tourniquet (200 mmHg) immediately prior to the exercise (3x5 minutes of occlusion, separated by 5 minutes of reperfusion). Creatine Kinase (CK), arm circumference, subjective pain (VAS score) and radial displacement (Tensiomyography, Dm) were assessed before IPC, pre-exercise, post-exercise, 20 minutes-, 2 hours-, 24 hours-, 48 hours- and 72 hours post-exercise. CK differed from baseline only in ECC at 48h (pexercise. After 24h, 48h and 72h, CK was increased in ECC compared to IPC+ECC (between groups: 24h: p=0.004, 48h: pexercise, when compared to IPC+ECC (between groups: all pexercise days in ECC (all peccentric exercise of the elbow flexors blunts EIMD and exercise-induced pain, while maintaining the contractile properties of the muscle.

  9. Optimising the Parallelisation of OpenFOAM Simulations

    Science.gov (United States)

    2014-06-01

    8GB DDR3-1600 Registered ECC memory Storage: 1TB SATA HDD plus network file system (NFS) server. OS: CentOS 6.5 CFD Software: OpenFOAM 2.2.2 with...E5 2687W – 8 cores per CPU @ 3.1GHz RAM: 16x 32GB DDR3-1333 Registered ECC memory Storage: 1TB SATA HDD plus 3x 3TB SATA HDD in RAID0 OS: Red Hat

  10. Formalization of Error-correcting Codes using SSReflect

    OpenAIRE

    Affeldt, Reynald

    2015-01-01

    By adding redundant information to transmitted data, error-correcting codes (ECCs) make it possible to communicate reliably over noisy channels. Minimizing redundancy and coding/decoding time has driven much research, culminating with Low-Density Parity-Check (LDPC) codes. Hard-disk storage, wifi communications, mobile phones, etc.: most modern devices now rely on ECCs and in particular LDPC codes. Yet, correctness guarantees are only provided by research papers of ever-growing complexity. On...

  11. Erwinia carotovora ssp. carotovora Infection Induced "Defense Lignin" Accumulation and Lignin Biosynthetic Gene Expression in Chinese Cabbage (Brassica rapa L. ssp. pekinensis)

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Erwinia carotovora subsp. carotovora (Ecc) infects and causes soft rot disease in hundreds of crop species including vegetables, flowers and fruits. Lignin biosynthesis has been implicated in defensive reactions to injury and pathogen Infection in plants. In this work, variations of lignin content and gene expression in the molecular interaction between Chinese cabbage and Ecc were investigated. H2O2 accumulation and peroxidase activity were detected by 3, 3'-Dimethoxybenzidine staining at mocked and Ecc-inoculated sites of Chinese cabbage leafstalks. Klason lignin content in inoculated plants increased by about 7.84%, 40.37%, and 43.13% more than that of the mocked site at 12, 24 and 72 h after inoculation, respectively. Gas chromatography detected more p-coumaryl (H) and less coniferyl (G) and sinapyl (S)monolignins in leafstalks of Chinese cabbage. All three monomers increased in Ecc-infected leafstalks, and the Ecc-induced "defense lignin" were composed of more G and H monolignins, and less S monolignin. After searching the expressed sequence tags (EST) data of Chinese cabbage, 12 genes putatively encoding enzymes involved in lignin biosynthesis were selected to study their expression. All of these genes could be Induced by mock inoculation and Ecc infection, while the gene expression lasted for several more hours in the infected samples than in mocked and untreated plants. Our results indicated that "defense lignin" was different from the developmental lignin in composition; G and S monolignins were significantly induced in plants in response to the soft rot Ecc; thus, lignin biosynthesis was differentially regulated and played a role in plant response to the soft rot Ecc.

  12. Effects of eccentric cycling and endurance training versus low cadence cycling and endurance training on muscle strength and cycling performance in trained individuals

    OpenAIRE

    Eidsheim, Hedda Øyeflaten

    2016-01-01

    Background: Recent studies have shown a positive effect of concurrent strength and endurance training on performance in cycling. Still, few studies have investigated the effect of eccentric cycling (ECC) and low cadence cycling (LCC) on muscle strength and determinants of cycling performance. Aim: Compare the effect of concurrent ECC and endurance training with concurrent LCC and endurance training on strength development, muscle thickness, and cycling performance in trained...

  13. Role of Candida albicans-Secreted Aspartyl Proteinases (Saps in Severe Early Childhood Caries

    Directory of Open Access Journals (Sweden)

    Wenqing Li

    2014-06-01

    Full Text Available Candida albicans is strongly associated with severe early childhood caries (S-ECC. However, the roles of secreted aspartyl proteinases (Saps, an important virulence factor of C. albicans, in the progress of S-ECC are not clear. In our study, the Saps activities were evaluated by the yeast nitrogen base–bovine serum albumi (YNB–BSA agar plate method and by the MTT method with bovine serum albumin (BSA as the substrate. Genotypes of C. albicans and gene expression of Sap1–5 were evaluated. The relationships of Saps activities and genotypes with S-ECC were analyzed. The results showed that enzyme activities of Saps in the S-ECC group were significantly higher than those in the caries free (CF group (p < 0.05. Genotypes A, B and C were detected in the S-ECC group, and genotypes A and C were detected in the CF group. In the genotype A group, Saps activity in the S-ECC group was significantly different from that in the CF group (p < 0.05. The gene expression level of Sap1 in the S-ECC group was significantly higher than that in the CF group (p = 0.001, while Sap4 expression was significantly lower than that in the CF group (p = 0.029. It can be concluded that Sap1–5 are the predominant proteinase genes expressed in C. albicans from dental biofilm and Sap1 may play an important role in the development of S-ECC.

  14. Early versus delayed umbilical cord clamping in infants with congenital heart disease: a pilot, randomized, controlled trial.

    Science.gov (United States)

    Backes, C H; Huang, H; Cua, C L; Garg, V; Smith, C V; Yin, H; Galantowicz, M; Bauer, J A; Hoffman, T M

    2015-10-01

    Delayed umbilical cord clamping (DCC) at birth may provide a better neonatal health status than early umbilical cord clamping (ECC). However, the safety and feasibility of DCC in infants with congenital heart disease (CHD) have not been tested. This was a pilot, randomized, controlled trial to establish the safety and feasibility of DCC in neonates with CHD. Pregnant women admitted >37 weeks gestational age with prenatal diagnosis of critical CHD were enrolled and randomized to ECC or DCC. For ECC, the umbilical cord was clamped cord was clamped ~120 s after delivery. Thirty infants were randomized at birth. No differences between the DCC and ECC groups were observed in gestational age at birth or time of surgery. No differences were observed across all safety measures, although a trend for higher peak serum bilirubin levels (9.2±2.2 vs 7.3±3.2 mg dl(-1), P=0.08) in the DCC group than in the ECC group was noted. Although similar at later time points, hematocrits were higher in the DCC than in the ECC infants during the first 72 h of life. The proportion of infants not receiving blood transfusions throughout hospitalization was higher in the DCC than in the ECC infants (43 vs 7%, log-rank test P=0.02). DCC in infants with critical CHD appears both safe and feasible, with fewer infants exposed to red blood cell transfusions than with ECC. A more comprehensive appraisal of this practice is warranted.

  15. Comparison of Oxygen Consumption in Rats During Uphill (Concentric) and Downhill (Eccentric) Treadmill Exercise Tests

    Science.gov (United States)

    Chavanelle, Vivien; Sirvent, Pascal; Ennequin, Gaël; Caillaud, Kévin; Montaurier, Christophe; Morio, Béatrice; Boisseau, Nathalie; Richard, Ruddy

    2014-01-01

    The study of the physiological adaptations of skeletal muscle in response to eccentric (ECC) contraction is based on protocols in which exercise intensities are determined relative to the concentric (CON) reference exercise (as percentage of the CON maximal oxygen consumption, or VO2max). In order to use similar exercise protocols in rats, we compared the VO2 values during uphill (CON) and downhill (ECC) running tests. VO2 was measured in 15 Wistar rats during incremental treadmill running exercises with different slopes: level (0%), positive (+15% incline: CON+15%) and negative (i15% incline: ECC-15%; and 130% incline: ECC-30%). Similar VO2 values were obtained in the ECC-30% and CON+15% running conditions at the three target speeds (15, 25 and 35 cm/sec). Conversely, VO2 values were lower (p VO2/ECC-15% VO2 ratios ranging from 1.86 to 2.05 at the three target speeds). Thus, doubling the downhill slope gradient in ECC condition leads to an oxygen consumption level that is not significantly different as in CON condition. These findings can be useful for designing animal research protocols to study the effects of ECC and CON exercise in ageing population or subjects suffering from cardiovascular diseases. Key Points VO2 in rats during treadmill race in eccentric and concentric conditions were measured. A novel breath-by-breath device allowing direct access to the animal was used. Three different slopes: +15%, -15% and -30% were used. VO2 values obtained in the -30% eccentric and the +15% concentric conditions were not significantly different. PMID:25177200

  16. Close-out report with links to abstracts

    Energy Technology Data Exchange (ETDEWEB)

    Marmar, Earl S. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2016-07-12

    This grant provided A/V support for two technical meetings of the Edge Coordinating Committee: 1) Nov 13, 2013 (co-located with the APS-DPP meeting in Denver, CO) https://ecc.mit.edu/fall-2013-technical-meeting#overlay-context=ecc-meetings 2) April 28-May 1, 2015 (embedded sessions in the Transport Task Force Meeting, Salem, MA) http://www-internal.psfc.mit.edu/TTF2015/index.html

  17. Current protocols in the generation of pluripotent stem cells: theoretical, methodological and clinical considerations

    OpenAIRE

    2009-01-01

    Brad B Swelstad, Candace L KerrInstitute for Cell Engineering, Department of Obstetrics and Gynecology, Johns Hopkins University, Baltimore, MA, USAAbstract: Pluripotent stem cells have been derived from various embryonic, fetal and adult sources. Embryonic stem cells (ESCs) and parthenogenic ESCs (pESCs) are derived from the embryo proper while embryonic germ cells (EGCs), embryonal carcinoma cells (ECCs), and germ-line stem cells (GSC) are produced from germ cells. ECCs were the first pluri...

  18. Giustizia allo specchio

    Directory of Open Access Journals (Sweden)

    Elisabetta Grande

    2013-07-01

    Full Text Available Non solo “giustizia” è un termine altamente polisemico, capace di mutare radicalmente connotazione secondo l’aggettivo che gli viene abbinato (giustizia distributiva, giustizia commutativa, giustizia contrattuale, giustizia civile ecc., ma è pure nozione con cui si sono misurate da secoli un gran numero di discipline (filosofia, diritto, politica, antropologia ecc., ognuna producendo un aggregato di significati settoriali, capaci ciascuno di fondare una tradizione e un’ideologia di ricerca.

  19. Biological restorations: an alternative esthetic treatment for restoration of severely mutilated primary anterior teeth.

    Science.gov (United States)

    N, Grewal; S, Reeshu

    2008-09-01

    Early childhood caries (ECC) affects more than one out of seven preschoolers and is more prevalent in lowincome families, who generally have limited access to dental services. The seriousness and societal costs of ECC continue to be a significant health issue for children from racial/ethnic minorities and from developing countries. Hence, a biological restoration seems to be a successful cost-effective alternative approach for treating such cases.

  20. Software Implementation of Elliptic Curve Encryption over Binary Field

    Institute of Scientific and Technical Information of China (English)

    ZHANG Xianfeng; QIN Zhiguang; ZHOU Shijie; LIU Jinde

    2003-01-01

    The mathematical theory for elliptic curve encryption based on optimal normal basis (ONB) over Fm2 is introduced. Then an elliptic curve cryptography(ECC) based encryption scheme is analyzed and designed. The mechanism for key exchange based on Diffie-Hellman is described in details for further applications. Based on these theoretic foundations, the software based on ECC is developed and an application is provided. The software is characterized by excellent security as well as high efficiency.

  1. Design of engineered cementitious composites for ductile seismic resistant elements

    Science.gov (United States)

    Kanda, Tetsushi

    This dissertation focuses on designing Engineered Cementitious Composite (ECC) to achieve high performance seismic resistant elements. To attain this goal, three major tasks have been accomplished. Task 1 aims at achieving new ECCs involving low cost fiber, which often involve fiber rupture in crack bridging, thus named as "Fiber Rupture Type ECC". Achieving the new ECC requires a new practical and comprehensive composite design theory. For this theory, single fiber behavior was first investigated. Specifically, fiber rupture in composite and chemical bond in fiber/matrix interface were experimentally examined and mathematically modeled. Then this model for single fiber behavior was implemented into a proposed bridging law, a theoretical model for relationship between fiber bridging stress of composite and Crack Opening Displacement (COD). This new bridging law was finally employed to establish a new composite design theory. Task 2 was initiated to facilitate structural interpretation of ECC's material behavior investigated in Task 1. For this purpose, uniaxial tensile behavior, one of the most important ECC's properties, was theoretically characterized with stress-strain relation from micromechanics view point. As a result, a theory is proposed to express ECC's tensile stress-strain relation in terms of micromechanics parameters of composites, such as bond strengths. Task 3 primarily demonstrates an integrated design scheme for ductile seismic elements that covers from micromechanics in single fiber level to structural design tool, such as with non-linear FEM analysis. The significance of this design scheme is that the influences of ECC's microstructure on element's structural performance is quantitatively captured. This means that a powerful tool is obtained for tailoring constitutive micromechanics parameters in order to maximize structural performance of elements. While the tool is still preliminary, completing this tool in future studies will enable one to

  2. Salivary pH and Buffering Capacity as Risk Markers for Early Childhood Caries: A Clinical Study

    OpenAIRE

    D. Jayaraj; Ganesan, S.

    2015-01-01

    ABSTRACT Background: The diagnostic utility of saliva is currently being explored in various branches of dentistry, remarkably in the field of caries research. This study was aimed to determine if assessment of salivary pH and buffering capacity would serve as reliable tools in risk prediction of early childhood caries (ECC). Materials and methods: Paraffin-stimulated salivary samples were collected from 50 children with ECC (group I) and 50 caries free children (group II). Salivary pH and bu...

  3. JPRS Report, Soviet Union, Political Affairs.

    Science.gov (United States)

    1989-12-12

    which was, incidentally, far from homo - geneous) grew stronger, the workforce expanded, together with its readiness for social protest, and the entire...provoking and promoting destabilization of the political situation in the republic. The Estonian Citizens’ Committees ( ECC ) are accused of...4. The accusation of adventurism and destabilization of the political situation is demagogical. The activity of the ECC is based on generally

  4. Hypoplasia-associated severe early childhood caries--a proposed definition.

    Science.gov (United States)

    Caufield, P W; Li, Y; Bromage, T G

    2012-06-01

    We propose a new classification of severe early childhood caries (S-ECC): hypoplasia-associated severe early childhood caries (HAS-ECC). This form of caries affects mostly young children living at or below poverty, characterized by structurally damaged primary teeth that are particularly vulnerable to dental caries. These predisposing developmental dental defects are mainly permutations of enamel hypoplasia (EHP). Anthropologists and dental researchers consider EHP an indicator for infant and maternal stresses including malnutrition, a variety of illnesses, and adverse birthing conditions. Differentiation of HAS-ECC from other forms of early childhood caries is warranted because of its distinct etiology, clinical presentation, and eventual management. Defining HAS-ECC has important clinical implications: Therapies that control or prevent other types of caries are likely to be less effective with HAS-ECC because the structural integrity of the teeth is compromised prior to their emergence into the oral cavity. By the time these children present to the dentist, the treatment options often become limited to surgical management under general anesthesia. To prevent HAS-ECC, dentists must partner with other health providers to develop interventions that begin with pregnant mothers, with the aim of eliminating or ameliorating the covariates accompanying poverty, including better pre- and post-natal care and nutrition.

  5. Secured Wireless Communication using Fuzzy Logic based High Speed Public-Key Cryptography (FLHSPKC

    Directory of Open Access Journals (Sweden)

    Arindam Sarkar

    2012-10-01

    Full Text Available In this paper secured wireless communication using fuzzy logic based high speed public-key cryptography (FLHSPKC has been proposed by satisfying the major issues likes computational safety, power management and restricted usage of memory in wireless communication. Wireless Sensor Network (WSN has several major constraints likes’ inadequate source of energy, restricted computational potentiality and limited memory. Though conventional Elliptic Curve Cryptography (ECC which is a sort of public-key cryptography used in wireless communication provides equivalent level of security like other existing public–key algorithm using smaller parameters than other but this traditional ECC does not take care of all these major limitations in WSN. In conventional ECC consider Elliptic curve point p, an arbitrary integer k and modulus m, ECC carry out scalar multiplication kP mod m, which takes about 80% of key computation time on WSN. In this paper proposed FLHSPKC scheme provides some novel strategy including novel soft computing based strategy to speed up scalar multiplication in conventional ECC and which in turn takes shorter computational time and also satisfies power consumption restraint, limited usage of memory without hampering the security level. Performance analysis of the different strategies under FLHSPKC scheme and comparison study with existing conventional ECC methods has been done.

  6. Design and Micromagnetic Simulation of Fe/L10-FePt/Fe Trilayer for Exchange Coupled Composite Bit Patterned Media at Ultrahigh Areal Density

    Directory of Open Access Journals (Sweden)

    Warunee Tipcharoen

    2015-01-01

    Full Text Available Exchange coupled composite bit patterned media (ECC-BPM are one candidate to solve the trilemma issues, overcome superparamagnetic limitations, and obtain ultrahigh areal density. In this work, the ECC continuous media and ECC-BPM of Fe/L10-FePt/Fe trilayer schemes are proposed and investigated based on the Landau-Lifshitz-Gilbert equation. The switching field, Hsw, of the hard phase in the proposed continuous ECC trilayer media structure is reduced below the maximum write head field at interlayer exchange coupling between hard and soft phases, Aex, higher than 20 pJ/m and its value is lower than that for continuous L10-FePt single layer media and L10-FePt/Fe bilayer. Furthermore, the Hsw of the proposed ECC-BPM is lower than the maximum write head field with exchange coupling coefficient between neighboring dots of 5 pJ/m and Aex over 10 pJ/m. Therefore, the proposed ECC-BPM trilayer has the highest potential and is suitable for ultrahigh areal density magnetic recording technology at ultrahigh areal density. The results of this work may be gainful idea for nanopatterning in magnetic media nanotechnology.

  7. The hexA gene of Erwinia carotovora encodes a LysR homologue and regulates motility and the expression of multiple virulence determinants.

    Science.gov (United States)

    Harris, S J; Shih, Y L; Bentley, S D; Salmond, G P

    1998-05-01

    We have identified a gene important for the regulation of exoenzyme virulence factor synthesis in the plant pathogen Erwinia carotovora ssp. carotovora (Ecc) and virulence and motility in Erwinia carotovora ssp. atroseptica (Eca). This gene, hexA (hyperproduction of exoenzymes), is a close relative of the Erwinia chrysanthemi (Echr) gene pecT and encodes a member of the LysR family of transcriptional regulators. hexA mutants in both Ecc and Eca produce abnormally high levels of the exoenzyme virulence factors pectate lyase, cellulase and protease. In addition, Eca hexA mutants show increased expression of the fliA and fliC genes and hypermotility. Consistent with a role as a global regulator, expression of hexA from even a low-copy plasmid can suppress exoenzyme production in Ecc and Eca and motility in Eca. Production of the quorum-sensing pheromone OHHL in Ecc hexA is higher throughout the growth curve compared with the wild-type strain. Overexpression of Ecc hexA also caused widespread effects in several strains of the opportunistic human pathogen, Serratia. Low-copy hexA expression resulted in repression of exoenzyme, pigment and antibiotic production and repression of the spreading phenotype. Finally, mutations in hexA were shown to increase Ecc or Eca virulence in planta.

  8. Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial.

    Science.gov (United States)

    Beyer, Rikke; Kongsgaard, Mads; Hougs Kjær, Birgitte; Øhlenschlæger, Tommy; Kjær, Michael; Magnusson, S Peter

    2015-07-01

    Previous studies have shown that eccentric training has a positive effect on Achilles tendinopathy, but few randomized controlled trials have compared it with other loading-based treatment regimens. To evaluate the effectiveness of eccentric training (ECC) and heavy slow resistance training (HSR) among patients with midportion Achilles tendinopathy. Randomized controlled trial; Level of evidence, 1. A total of 58 patients with chronic (>3 months) midportion Achilles tendinopathy were randomized to ECC or HSR for 12 weeks. Function and symptoms (Victorian Institute of Sports Assessment-Achilles), tendon pain during activity (visual analog scale), tendon swelling, tendon neovascularization, and treatment satisfaction were assessed at 0 and 12 weeks and at the 52-week follow-up. Analyses were performed on an intention-to-treat basis. Both groups showed significant (P tendon thickness and neovascularization. None of these robust clinical and structural improvements differed between the ECC and HSR groups. However, patient satisfaction tended to be greater after 12 weeks with HSR (100%) than with ECC (80%; P = .052) but not after 52 weeks (HSR, 96%; ECC, 76%; P = .10), and the mean training session compliance rate was 78% in the ECC group and 92% in the HSR group, with a significant difference between groups (P tendinopathy and that the latter tends to be associated with greater patient satisfaction after 12 weeks but not after 52 weeks. © 2015 The Author(s).

  9. EFFECT OF HEAT PRECONDITIONING BY MICROWAVE HYPERTHERMIA ON HUMAN SKELETAL MUSCLE AFTER ECCENTRIC EXERCISE

    Directory of Open Access Journals (Sweden)

    Norio Saga

    2008-03-01

    Full Text Available The purpose of this study was to clarify whether heat preconditioning results in less eccentric exercise-induced muscle damage and muscle soreness, and whether the repeated bout effect is enhanced by heat preconditioning prior to eccentric exercise. Nine untrained male volunteers aged 23 ± 3 years participated in this study. Heat preconditioning included treatment with a microwave hyperthermia unit (150 W, 20 min that was randomly applied to one of the subject's arms (MW; the other arm was used as a control (CON. One day after heat preconditioning, the subjects performed 24 maximal isokinetic eccentric contractions of the elbow flexors at 30°·s-1 (ECC1. One week after ECC1, the subjects repeated the procedure (ECC2. After each bout of exercise, maximal voluntary contraction (MVC, range of motion (ROM of the elbow joint, upper arm circumference, blood creatine kinase (CK activity and muscle soreness were measured. The subjects experienced both conditions at an interval of 3 weeks. MVC and ROM in the MW were significantly higher than those in the CON (p < 0.05 for ECC1; however, the heat preconditioning had no significant effect on upper arm circumference, blood CK activity, or muscle soreness following ECC1 and ECC2. Heat preconditioning may protect human skeletal muscle from eccentric exercise-induced muscle damage after a single bout of eccentric exercise but does not appear to promote the repeated bout effect after a second bout of eccentric exercise

  10. Clinical comparison of dose calculation using the enhanced collapsed cone algorithm vs. a new Monte Carlo algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Fotina, Irina; Kragl, Gabriele; Kroupa, Bernhard; Trausmuth, Robert; Georg, Dietmar [Medical Univ. Vienna (Austria). Division of Medical Radiation Physics, Dept. of Radiotherapy

    2011-07-15

    Comparison of the dosimetric accuracy of the enhanced collapsed cone (eCC) algorithm with the commercially available Monte Carlo (MC) dose calculation for complex treatment techniques. A total of 8 intensity-modulated radiotherapy (IMRT) and 2 stereotactic body radiotherapy (SBRT) lung cases were calculated with eCC and MC algorithms with the treatment planning systems (TPS) Oncentra MasterPlan 3.2 (Nucletron) and Monaco 2.01 (Elekta/CMS). Fluence optimization as well as sequencing of IMRT plans was primarily performed using Monaco. Dose prediction errors were calculated using MC as reference. The dose-volume histrogram (DVH) analysis was complemented with 2D and 3D gamma evaluation. Both algorithms were compared to measurements using the Delta4 system (Scandidos). Recalculated with eCC IMRT plans resulted in lower planned target volume (PTV) coverage, as well as in lower organs-at-risk (OAR) doses up to 8%. Small deviations between MC and eCC in PTV dose (1-2%) were detected for IMRT cases, while larger deviations were observed for SBRT (up to 5%). Conformity indices of both calculations were similar; however, the homogeneity of the eCC calculated plans was slightly better. Delta4 measurements confirmed high dosimetric accuracy of both TPS. Mean dose prediction errors < 3% for PTV suggest that both algorithms enable highly accurate dose calculations under clinical conditions. However, users should be aware of slightly underestimated OAR doses using the eCC algorithm. (orig.)

  11. Cataract surgery in previously vitrectomized eyes.

    Science.gov (United States)

    Akinci, A; Batman, C; Zilelioglu, O

    2008-05-01

    To evaluate the results of extracapsular cataract extraction (ECCE) and phacoemulsification (PHACO) performed in previously vitrectomized eyes. In this retrospective study, 56 vitrectomized eyes that had ECCE and 60 vitrectomized eyes that had PHACO were included in the study group while 65 eyes that had PHACO in the control group. The evaluated parameters were the incidence of intra-operative and postoperative complications (IPC) and visual outcomes. Chi-squared, independent samples and paired samples tests were used for comparing the results. Deep anterior chamber (AC) was significantly more common in the PHACO group of vitrectomized eyes (PGVE) and observed in eyes that had undergone extensive vitreous removal (p ECCE group and the PGVE (p > 0.05). Some of the intra-operative conditions such as posterior synechiae, primary posterior capsular opacification (PCO) and postoperative complications such as retinal detachment (RD), PCO were significantly more common in vitrectomized eyes than the controls (p ECCE group and the PGVE (p > 0.05). Deep AC is more common in eyes with extensive vitreous removal during PHACO than ECCE. Decreasing the bottle height is advised in this case. Except for this, the results of ECCE and PHACO are similar in previously vitrectomized eyes. Posterior synechiaes, primary and postoperative PCO and RD are more common in vitrectomized eyes than the controls.

  12. Hospital-based community cataract surgery: comparison of visual outcomes between conventional extra-capsular cataract extraction and small incision cataract surgery.

    Science.gov (United States)

    Karki, P; Shrestha, K; Shrestha, J B

    2009-01-01

    the small-incision cataract surgery is gaining popularity among the ophthalmic surgeons. to compare the visual outcome of conventional extra-capsular cataract extraction (ECCE) and small-incision cataract surgery (SICS) in a hospital based community cataract program. aprospective interventional study without randomization was carried out including the patients undergoing cataract surgery by either conventional ECCE or manual SICS. They were followed up for 6 weeks postoperatively. The visual outcomes were compared between the two groups. the statistical program Epi-Info version 2000 was used to analyze the data. Mean values with standard deviations, 95% CI and p value were calculated. The p value ofECCE and 41 (M: F=15:26) SICS (RR= 0.71, 95% CI=0.42-1.2, p value=0.16). Unaided visual acuity on the 1st postoperative day in the ECCE group was e"6/ 18 in 22.7%,ECCE group was e"6/18 in 79.5%,ECCE and SICS are good procedures for hospital based community cataract surgery but within the 6 weeks postoperative period SICS gives better visual outcome. Remarkably higher number of female patients can be provided service in a hospital based community cataract programme as compared to males.

  13. Social costs of two cataract surgical techniques in Brazil.

    Science.gov (United States)

    Kara-Junior, Newton; Parede, Tais Renata Ribeira; Santhiago, Marcony Rodrigues; Santiago, Marcony Rodrigues; Espindola, Rodrigo França; Mazurek, Maysa Godoy Gomes; Carvalho, Regina de Souza

    2010-10-01

    To compare postoperative social costs of two cataract surgical techniques, phacoemulsification (PHACO) and extracapsular extraction (ECCE). Prospective randomized intervention study including 205 patients, of which 101 underwent PHACO and 104 ECCE in the public service, in the city of São Paulo, Southeastern Brazil, in 2002. The socioeconomic impact of these surgical procedures was assessed based on postoperative costs for patients, employers and social security. Comparisons between the two groups studied were performed using the chi-square test or Mann-Whitney test, when appropriate. A 5% significance level was set. Hospital and eyeglasses costs for PHACO were lower than for ECCE patients, with a mean difference of US$ 16.74. Costs to employers related to medical leave for the first 15 days of absence and costs of caregivers in the form of absence from work to attend postoperative follow-up visits were on average US$ 0.18 lower in PHACO compared to ECCE group. The estimated Social Security expenditure per patient undergoing surgery was US$ 6.57 and US$ 51.15 in PHACO and ECCE groups, respectively. The average saving with PHACO compared to ECCE technique was US$ 61.50 for employers, patients, caregivers and Social Security.

  14. Early childhood caries in preschool children of Kosovo - a serious public health problem

    Directory of Open Access Journals (Sweden)

    Meqa Kastriot

    2010-12-01

    Full Text Available Abstract Background Even though it has been widely studied, early childhood caries (ECC remains a serious public health problem, especially in countries where there is no national program of oral health assessment and no genuine primary oral health care, such as in Kosovo. The purpose of this study was to assess the prevalence of ECC and analyze caries risk factors. Methods The subjects were 1,008 preschool children, selected by stratified random cluster sampling, in the municipality of Prishtina, capital of Kosovo. Data were collected through clinical examination and interviews. Dmft data were recorded according to WHO criteria. Bacterial examination (CRT bacteria test and plaque test of Greene-Vermillion were used. Results The mean dmft of preschool children was found to be 5.8. The prevalence of ECC was 17.36%, with a mean dmft of 11 ± 3.6. Streptococcus mutans prevalence in ECC children was 98%. A significant correlation between dmft and S mutans counts (≥105 CFU/mL saliva was demonstrated. A correlation was also found between daily sweets consumption and dmft in children with ECC (P P Conclusion The prevalence of ECC was high among preschool children in the municipality of Kosovo. We recommend increasing parents' knowledge of proper feeding habits and oral health practices, and increasing preschool children's accessibility to dental services.

  15. Glaucoma de pressão normal e espessura corneana central

    Directory of Open Access Journals (Sweden)

    Sakata Kenji

    2002-01-01

    Full Text Available Objetivo: Este estudo tem como objetivo investigar a existência de diferença da espessura corneana central (ECC em pacientes com glaucoma de pressão normal (GPN, glaucoma crônico simples (GCS e pacientes normais (Controle. Métodos: Foram avaliados 113 pacientes dos quais 40 apresentavam GPN, 51 eram normais (Controles e 22 apresentavam GCS. Todos os pacientes foram submetidos a exame oftalmológico completo e tiveram aferidas sua Po (Goldmann e ECC (Topcon SP-2000P. Resultados: A média da espessura corneana central (ECC dos pacientes com GPN foi de 500,95 m (d.p. 28,65 m, o grupo controle teve média de 521,11 m (d.p. de 43,30 m e o grupo de GCS apresentou média de 522,23 m (d.p. de 27,87 m.. O grupo de GPN apresentou uma ECC significativamente menor quando comparado com os grupo controle (p = 0,01 e GCS (p=0,006. Entre os grupos controle e GCS não houve diferença estatística significativa (p = 0,91. Conclusão: Observou-se que numa amostra da população brasileira a ECC dos olhos com GPN é significativamente menor do que a ECC dos pacientes com GCS e do grupo controle.

  16. Effect of eccentric versus concentric exercise training on mitochondrial function.

    Science.gov (United States)

    Isner-Horobeti, Marie-Eve; Rasseneur, Laurence; Lonsdorfer-Wolf, Evelyne; Dufour, Stéphane Pascal; Doutreleau, Stéphane; Bouitbir, Jamal; Zoll, Joffrey; Kapchinsky, Sophia; Geny, Bernard; Daussin, Frédéric Nicolas; Burelle, Yan; Richard, Ruddy

    2014-11-01

    The effect of eccentric (ECC) versus concentric (CON) training on metabolic properties in skeletal muscle is understood poorly. We determined the responses in oxidative capacity and mitochondrial H2 O2 production after eccentric (ECC) versus concentric (CON) training performed at similar mechanical power. Forty-eight rats performed 5- or 20-day eccentric (ECC) or concentric (CON) training programs. Mitochondrial respiration, H2 O2 production, citrate synthase activity (CS), and skeletal muscle damage were assessed in gastrocnemius (GAS), soleus (SOL) and vastus intermedius (VI) muscles. Maximal mitochondrial respiration improved only after 20 days of concentric (CON) training in GAS and SOL. H2 O2 production increased specifically after 20 days of eccentric ECC training in VI. Skeletal muscle damage occurred transiently in VI after 5 days of ECC training. Twenty days of ECC versus CON training performed at similar mechanical power output do not increase skeletal muscle oxidative capacities, but it elevates mitochondrial H2 O2 production in VI, presumably linked to transient muscle damage. © 2014 Wiley Periodicals, Inc.

  17. Multi-location gram-positive and gram-negative bacterial protein subcellular localization using gene ontology and multi-label classifier ensemble

    Science.gov (United States)

    2015-01-01

    Background It has become a very important and full of challenge task to predict bacterial protein subcellular locations using computational methods. Although there exist a lot of prediction methods for bacterial proteins, the majority of these methods can only deal with single-location proteins. But unfortunately many multi-location proteins are located in the bacterial cells. Moreover, multi-location proteins have special biological functions capable of helping the development of new drugs. So it is necessary to develop new computational methods for accurately predicting subcellular locations of multi-location bacterial proteins. Results In this article, two efficient multi-label predictors, Gpos-ECC-mPLoc and Gneg-ECC-mPLoc, are developed to predict the subcellular locations of multi-label gram-positive and gram-negative bacterial proteins respectively. The two multi-label predictors construct the GO vectors by using the GO terms of homologous proteins of query proteins and then adopt a powerful multi-label ensemble classifier to make the final multi-label prediction. The two multi-label predictors have the following advantages: (1) they improve the prediction performance of multi-label proteins by taking the correlations among different labels into account; (2) they ensemble multiple CC classifiers and further generate better prediction results by ensemble learning; and (3) they construct the GO vectors by using the frequency of occurrences of GO terms in the typical homologous set instead of using 0/1 values. Experimental results show that Gpos-ECC-mPLoc and Gneg-ECC-mPLoc can efficiently predict the subcellular locations of multi-label gram-positive and gram-negative bacterial proteins respectively. Conclusions Gpos-ECC-mPLoc and Gneg-ECC-mPLoc can efficiently improve prediction accuracy of subcellular localization of multi-location gram-positive and gram-negative bacterial proteins respectively. The online web servers for Gpos-ECC-mPLoc and Gneg-ECC

  18. A retrospective comparative study of minimally invasive extracorporeal circulation versus conventional extracorporeal circulation in emergency coronary artery bypass surgery patients: a single surgeon analysis.

    Science.gov (United States)

    Rufa, Magdalena; Schubel, Jens; Ulrich, Christian; Schaarschmidt, Jan; Tiliscan, Catalin; Bauer, Adrian; Hausmann, Harald

    2015-07-01

    At the moment, the main application of minimally invasive extracorporeal circulation (MiECC) is reserved for elective cardiac operations such as coronary artery bypass grafting (CABG) and/or aortic valve replacement. The purpose of this study was to compare the outcome of emergency CABG operations using either MiECC or conventional extracorporeal circulation (CECC) in patients requiring emergency CABG with regard to the perioperative course and the occurrence of major adverse cardiac and cerebral events (MACCE). We analysed the emergency CABG operations performed by a single surgeon, between January 2007 and July 2013, in order to exclude the differences in surgical technique. During this period, 187 emergency CABG patients (113 MiECC vs 74 CECC) were investigated retrospectively with respect to the following parameters: in-hospital mortality, MACCE, postoperative hospital stay and perioperative transfusion rate. The mean logistic European System for Cardiac Operative Risk Evaluation was higher in the CECC group (MiECC 12.1 ± 16 vs CECC 15.0 ± 20.8, P = 0.15) and the number of bypass grafts per patient was similar in both groups (MiECC 2.94 vs CECC 2.93). There was no significant difference in the postoperative hospital stay or in major postoperative complications. The in-hospital mortality was higher in the CECC group 6.8% versus MiECC 4.4% (P = 0.48). The perioperative transfusion rate was lower with MiECC compared with CECC (MiECC 2.6 ± 3.2 vs CECC 3.8 ± 4.2, P = 0.025 units of blood per patient). In our opinion, the use of MiECC in urgent CABG procedures is safe, feasible and shows no disadvantages compared with the use of CECC. Emergency operations using the MiECC system showed a significantly lower blood transfusion rate and better results concerning the unadjusted in-hospital mortality. © The Author 2015. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  19. Status of Issues in U.S. Edge-Plasma Research and Priority Topics for the Next Five Years

    Energy Technology Data Exchange (ETDEWEB)

    Bateman, G; Chang, C; Fenstermacher, M; Guzdar, P; Hahm, T S; Krasheninnikov, S; Kritz, A; Rognlien, T D; Schnack, D; Schultz, D; Snyder, P; Stotler, D; Terry, J; Ulrickson, M; Bolton, C

    2005-03-16

    The Edge Coordinating Committee (ECC) was formed in July 14-15, 2004 when OFES Theory Team invited 14 plasma researchers to a two-day meeting in Germantown, MD to discuss the state of edge-plasma research in the U.S. with a focus on theory and modeling (see http://www.mfescience.org/ecc/ ecc/). At that time, OFES tasked the ECC with providing, in about a six month period, a report on the present status of key issues in this area together with a roadmap of what range of activities should be undertaken in the next five years to resolve these issues. This document is a response to that charge. Future edge-plasma research described here is assumed to fit into a budget constraint of a ''flat budget,'' with some additional activities cited for budget increases of as much as 50%. To obtain some measure of the relative fraction of OFES Theory funding presently devoted to edge plasma research, the OFES Theory Team informally surveyed funded work they support in this area at National Labs, Universities, and industry. John Mandrekas reported to us that approximately 10% of the present budget goes to edge-physics areas at 10 institutions, for a total of {approx}$2.5M each year. While not explicitly estimated, we note that there are also important edge plasma projects in the Plasma Technology program, especially related to plasma/material sputtering interactions, near-surface plasma chemistry and transport, and impurity transport. Likewise, the Confinement Program has important efforts in interpreting edge-plasma data through modeling codes. This initial status/roadmap work of the ECC is complimentary to the Fusion Energy Science Sciences Advisory Committee (FESAC) Panel on Program Priorities (see http://www.mfescience.org/fesac/ fesac/). This Panel is charged with identifying major science and technology issues for all of controlled fusion and also with recommending campaigns to address these issues. The Panel has organized their report along six thematic

  20. Blood flow restriction prevents muscle damage but not protein synthesis signaling following eccentric contractions.

    Science.gov (United States)

    Sudo, Mizuki; Ando, Soichi; Poole, David C; Kano, Yutaka

    2015-07-01

    There is a growing body of evidence to suggest that resistance training exercise combined with blood flow restriction (BFR) increases muscle size and strength in humans. Eccentric contraction (ECC) frequently induces severe muscle damage. However, it is not known whether and to what extent muscle damage occurs following ECC + BFR due to the difficulty of conducting definitive invasive studies. The purpose of this study was to examine muscle fiber damage following ECC + BFR at the cellular level. High-intensity ECC was purposefully selected to maximize the opportunity for muscle damage and hypertrophic signaling in our novel in vivo animal model. Male Wistar rats were assigned randomly to the following groups: ECC and ECC + BFR at varying levels of occlusion pressure (140, 160, and 200 Torr). In all conditions, electrical stimulation was applied to the dorsiflexor muscles simultaneously with electromotor-induced plantar flexion. We observed severe histochemical muscle fiber damage (area of damaged fibers/total fiber area analyzed) following ECC (26.4 ± 4.0%). Surprisingly, however, muscle damage was negligible following ECC + BFR140 (2.6 ± 1.2%), ECC+BFR160 (3.0 ± 0.5%), and ECC + BFR200 (0.2 ± 0.1%). Ribosomal S6 kinase 1 (S6K1) phosphorylation, a downstream target of rapamycin (mTOR)-phosphorylation kinase, increased following ECC + BFR200 as well as ECC. In contrast, S6K1 phosphorylation was not altered by BFR alone. The present findings suggest that ECC combined with BFR, even at high exercise intensities, may enhance muscle protein synthesis without appreciable muscle fiber damage.

  1. Early Childhood Caries and Body Mass Index in Young Children from Low Income Families

    Directory of Open Access Journals (Sweden)

    Maria Goretti Queiroz

    2013-03-01

    Full Text Available The relationship between early childhood caries (ECC and obesity is controversial. This cross-sectional survey investigated this association in children from low-income families in Goiania, Goias, Brazil and considered the role of several social determinants. A questionnaire examining the characteristics of the children and their families was administered to the primary caregiver during home visits. In addition, children (approximately 6 years of age had their height, weight, and tooth condition assessed. The primary ECC outcome was categorized as one of the following: caries experience (decayed, missing, filled tooth: “dmft” index > 0, active ECC (decayed teeth > 0, or active severe ECC (decayed teeth ≥ 6. Descriptive, bivariate and logistic regression analyses were conducted. The participants in the current study consisted of 269 caregiver-child dyads, 88.5% of whom were included in the Family Health Program. Caregivers were mostly mothers (67.7%, were 35.3 ± 10.0 years old on average and had 9.8 ± 3.1 years of formal education. The mean family income was 2.3 ± 1.5 times greater than the Brazilian minimum wage. On average, the children in the current study were 68.7 ± 3.8 months old. Of these, 51.7% were boys, 23.4% were overweight or obese, 45.0% had active ECC, and 17.1% had severe ECC. The average body mass index (BMI of the children was 15.9 ± 2.2, and their dmft index was 2.5 ± 3.2. BMI was not associated with any of the three categories of dental caries (p > 0.05. In contrast, higher family incomes were significantly associated with the lack of caries experience in children (OR 1.22, 95%CI 1.01–1.50, but the mother’s level of education was not significantly associated with ECC.

  2. Researches of oral microbiota associated with, early-childhood caries%低龄儿童龋与其相关致病菌的研究进展

    Institute of Scientific and Technical Information of China (English)

    杨晓琼

    2011-01-01

    低龄儿童龋(ECC)是一种早期累及幼儿上颌乳前牙的严重龋损,预防其发生发展是世界卫生组织在全球范围内进行龋病预防的重要工作。致龋菌在ECC发生中起主要作用,其中变异链球菌是ECC重要的致病菌,研究主要集中在该类微生物的定植、传播和基因型;放线菌和乳杆菌是ECC儿童口腔的优势菌群,白色假丝酵母菌和双歧杆菌在儿童口腔的定植与ECC的发生相关;随着分子生物学技术的进一步成熟,对ECC病因微生物的了解逐渐深入到菌斑微生态方面,本文将对以上方面的研究进展作一综述。%Early childhood caries (ECC) is an extremely destructive form of caries involving maxillary primary anterior teeth. Preventing ECC is an important work on caries prevention in worldwide by the World Health Organization. Cariogenic bacteria are considered the major etiologic agent in the development of ECC. Streptococcus mutans is the important cariogenic bacteria of ECC, the recent researches are on its colonization, transmission and genotypes. Actinomyces and Lactobacillus are the dominant microorganisms in the oral cavities of children with ECC. The colonization of Candida albicans and Bifidobacterium is associated with ECC. With the development of molecular biology techniques, studies are to the plaque microflora. This review presented the recent researches on the above aspects.

  3. [Genotypic diversity of Streptococcus sobrinus in 3 to 4-year-old children suffering with severe early childhood caries].

    Science.gov (United States)

    Qin, Xiu-rong; Zhou, Qiong; Qin, Man

    2009-06-01

    To evaluate the genotypic diversity of Streptococcus sobrinus (Ss) between children suffering with severe early childhood caries (S-ECC) and caries-free children by arbitrarily primed-polymerase chain reaction (AP-PCR). A total of 178 children aged from 42 to 54 months were recruited from 14 urban kindergartens. The S-ECC group contained 87 children with more than 5 decayed teeth, and the control group was composed of 91 caries-free children. Stimulated whole saliva was collected by chewing paraffin. All mutans streptococcus isolates were subcultured, biochemically characterised and identified by PCR as Streptococcus mutans (Sm) and Ss. Then the Ss isolates were genotyped by AP-PCR. The frequency of Ss detection was 18% in S-ECC children, which was significantly higher than 3% in caries-free children (P < 0.01). Twenty-two distinct genotypes of Ss were identified from 53 clinical isolates. In S-ECC group, one to three genotypes of Ss were detected in each saliva sample. Only one genotype of Ss was detected in all the caries-free children. One genotype of Ss were shared by three S-ECC children. The genotypes of isolates in S-ECC group were relate to decayed-missing-filled teeth (r = 0.50, P < 0. 05). The rate of Ss detection was significantly higher in S-ECC children than in caries-free children. Isolates of Ss displayed genetic polymorphism. The multi-genotypes of Ss was related to differences in caries susceptibility. Strains of Ss with same genotype were present in unrelated subjects.

  4. Cultivable anaerobic microbiota of severe early childhood caries.

    Science.gov (United States)

    Tanner, A C R; Mathney, J M J; Kent, R L; Chalmers, N I; Hughes, C V; Loo, C Y; Pradhan, N; Kanasi, E; Hwang, J; Dahlan, M A; Papadopolou, E; Dewhirst, F E

    2011-04-01

    Severe early childhood caries (ECC), while strongly associated with Streptococcus mutans using selective detection (culture, PCR), has also been associated with a widely diverse microbiota using molecular cloning approaches. The aim of this study was to evaluate the microbiota of severe ECC using anaerobic culture. The microbial composition of dental plaque from 42 severe ECC children was compared with that of 40 caries-free children. Bacterial samples were cultured anaerobically on blood and acid (pH 5) agars. Isolates were purified, and partial sequences for the 16S rRNA gene were obtained from 5,608 isolates. Sequence-based analysis of the 16S rRNA isolate libraries from blood and acid agars of severe ECC and caries-free children had >90% population coverage, with greater diversity occurring in the blood isolate library. Isolate sequences were compared with taxon sequences in the Human Oral Microbiome Database (HOMD), and 198 HOMD taxa were identified, including 45 previously uncultivated taxa, 29 extended HOMD taxa, and 45 potential novel groups. The major species associated with severe ECC included Streptococcus mutans, Scardovia wiggsiae, Veillonella parvula, Streptococcus cristatus, and Actinomyces gerensceriae. S. wiggsiae was significantly associated with severe ECC children in the presence and absence of S. mutans detection. We conclude that anaerobic culture detected as wide a diversity of species in ECC as that observed using cloning approaches. Culture coupled with 16S rRNA identification identified over 74 isolates for human oral taxa without previously cultivated representatives. The major caries-associated species were S. mutans and S. wiggsiae, the latter of which is a candidate as a newly recognized caries pathogen.

  5. Evaluation of salivary nitric oxide level in children with early childhood caries

    Directory of Open Access Journals (Sweden)

    A R Senthil Eagappan

    2016-01-01

    Full Text Available Background: Nitric oxide (NO, a highly reactive radical, participates in the nonspecific natural defense mechanism of the oral cavity. The present study was attempted to evaluate the salivary NO levels in 4–5 year-old children with early childhood caries (ECC. The objective of the present study was to assess the salivary NO concentration in children with different caries activity. Materials and Methods: The study included 120 healthy 4–5 year-old children and they were equally divided into three groups based on decayed, missing, filled surfaces (dmfs score; forty caries-free children (control group, forty children with dmfs 1–5 (ECC group, and forty with dmfs ≥6 (severe ECC group. Saliva collected was measured for NO concentration by Griess reaction method. The obtained data were analyzed by ANOVA and Pearson's correlation coefficient. Results: The mean level of NO in the saliva of the control group was 51.2 ± 8.3457 and that of ECC and severe ECC were 47.1 ± 5.2614 and 33.625 ± 4.6942, respectively. The mean salivary NO concentration was significantly higher in healthy controls when compared to children with ECC and severe ECC. Moreover, a negative correlation (r = −0.6658 was observed between the salivary NO level and the mean dmfs, suggesting that as the salivary NO level decreases, the caries incidence increases. Conclusion: The obtained results support the antimicrobial activity of salivary NO and also suggest that an increase in NO production might contribute to lower the caries occurrence in children.

  6. Rate of force development as a measure of muscle damage.

    Science.gov (United States)

    Peñailillo, L; Blazevich, A; Numazawa, H; Nosaka, K

    2015-06-01

    This study tested the hypothesis that rate of force development (RFD) would be a more sensitive indirect marker of muscle damage than maximum voluntary isometric contraction (MVC) peak torque. Ten men performed one concentric cycling and two eccentric cycling (ECC1, ECC2) bouts for 30 min at 60% of maximal concentric power output with 2 weeks between bouts. MVC peak torque, RFD, and vastus lateralis electromyogram amplitude and mean frequency were measured during a knee extensor MVC before, immediately after and 1-2 days after each bout. The magnitude of decrease in MVC peak torque after exercise was greater (P < 0.05) for ECC1 (11-25%) than concentric cycling (2-12%) and ECC2 (0-16%). Peak RFD and RFD from 0-30 ms, 0-50 ms, 0-100 ms, to 0-200 ms decreased (P < 0.05) immediately after all cycling bouts without significant differences between bouts, but RFD at 100-200 ms interval (RFD(100-200)) decreased (P < 0.05) at all time points after ECC1 (24-32%) and immediately after ECC2 (23%), but did not change after CONC. The magnitude of decrease in RFD(100-200) was 7-19% greater than that of MVC peak torque after ECC1 (P < 0.05). It is concluded that RFD(100-200) is a more specific and sensitive indirect marker of eccentric exercise-induced muscle damage than MVC peak torque.

  7. Assessment Analysis and Forecasting for Security Early Warning of Energy Consumption Carbon Emissions in Hebei Province, China

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    Yi Liang

    2017-03-01

    Full Text Available Against the backdrop of increasingly serious global climate change and the development of the low-carbon economy, the coordination between energy consumption carbon emissions (ECCE and regional population, resources, environment, economy and society has become an important subject. In this paper, the research focuses on the security early warning of ECCE in Hebei Province, China. First, an assessment index system of the security early warning of ECCE is constructed based on the pressure-state-response (P-S-R model. Then, the variance method and linearity weighted method are used to calculate the security early warning index of ECCE. From the two dimensions of time series and spatial pattern, the security early warning conditions of ECCE are analyzed in depth. Finally, with the assessment analysis of the data from 2000 to 2014, the prediction of the security early warning of carbon emissions from 2015 to 2020 is given, using a back propagation neural network based on a kidney-inspired algorithm (KA-BPNN model. The results indicate that: (1 from 2000 to 2014, the security comprehensive index of ECCE demonstrates a fluctuating upward trend in general and the trend of the alarm level is “Severe warning”–“Moderate warning”–“Slight warning”; (2 there is a big spatial difference in the security of ECCE, with relatively high-security alarm level in the north while it is relatively low in the other areas; (3 the security index shows the trend of continuing improvement from 2015 to 2020, however the security level will remain in the state of “Semi-secure” for a long time and the corresponding alarm is still in the state of “Slight warning”, reflecting that the situation is still not optimistic.

  8. Control of postharvest soft rot caused by Erwinia carotovora of vegetables by a strain of Bacillus amyloliquefaciens and its potential modes of action.

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    Zhao, Yancun; Li, Pengxia; Huang, Kaihong; Wang, Yuning; Hu, Huali; Sun, Ya

    2013-03-01

    Erwinia carotovora subsp. carotovora (Ecc), the causal agent of bacterial soft rot, is one of the destructive pathogens of postharvest vegetables. In this study, a bacterial isolate (BGP20) from the vegetable farm soil showed strong antagonistic activity against Ecc in vitro, and its twofold cell-free culture filtrate showed excellent biocontrol effect in controlling the postharvest bacterial soft rot of potatoes at 25 °C. The anti-Ecc metabolites produced by the isolate BGP20 had a high resistance to high temperature, UV-light and protease K. Based on the colonial morphology, cellular morphology, sporulation, and partial nucleotide sequences of 16S rRNA and gyrB gene, the isolate BGP20 was identified as Bacillus amyloliquefaciens subsp. plantarum. Further in vivo assays showed that the BGP20 cell culture was more effective in controlling the postharvest bacterial soft rot of green peppers and Chinese cabbages than its twofold cell-free culture filtrate. In contrast, the biocontrol effect and safety of the BGP20 cell culture were very poor on potatoes. In the wounds of potatoes treated with both the antagonist BGP20 and the pathogen Ecc, the viable count of Ecc was 31,746 times that of BGP20 at 48 h of incubation at 25 °C. But in the wounds of green peppers, the viable count of BGP20 increased 182.3 times within 48 h, and that of Ecc increased only 51.3 %. In addition, the treatment with both BGP20 and Ecc induced higher activity of phenylalanine ammonia-lyase (PAL) than others in potatoes. But the same treatment did not induce an increase of PAL activity in green peppers. In conclusion, the present study demonstrated that the isolate BGP20 is a promising candidate in biological control of postharvest bacterial soft rot of vegetables, but its main mode of action is different among various vegetables.

  9. Evaluation of salivary nitric oxide level in children with early childhood caries

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    Senthil Eagappan, AR; Rao, V. Arun Prasad; Sujatha, S.; Senthil, D.; Sathiyajeeva, J.; Rajaraman, G.

    2016-01-01

    Background: Nitric oxide (NO), a highly reactive radical, participates in the nonspecific natural defense mechanism of the oral cavity. The present study was attempted to evaluate the salivary NO levels in 4–5 year-old children with early childhood caries (ECC). The objective of the present study was to assess the salivary NO concentration in children with different caries activity. Materials and Methods: The study included 120 healthy 4.5 year-old children and they were equally divided into three groups based on decayed, missing, filled surfaces (dmfs) score; forty caries-free children (control group), forty children with dmfs 1.5 (ECC group), and forty with dmfs ⩾6 (severe ECC group). Saliva collected was measured for NO concentration by Griess reaction method. The obtained data were analyzed by ANOVA and Pearson's correlation coefficient. Results: The mean level of NO in the saliva of the control group was 51.2 ± 8.3457 and that of ECC and severe ECC were 47.1 ± 5.2614 and 33.625 ± 4.6942, respectively. The mean salivary NO concentration was significantly higher in healthy controls when compared to children with ECC and severe ECC. Moreover, a negative correlation (r = −0.6658) was observed between the salivary NO level and the mean dmfs, suggesting that as the salivary NO level decreases, the caries incidence increases. Conclusion: The obtained results support the antimicrobial activity of salivary NO and also suggest that an increase in NO production might contribute to lower the caries occurrence in children. PMID:27605992

  10. Early childhood caries and body mass index in young children from low income families.

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    Costa, Luciane Rezende; Daher, Anelise; Queiroz, Maria Goretti

    2013-03-05

    The relationship between early childhood caries (ECC) and obesity is controversial. This cross-sectional survey investigated this association in children from low-income families in Goiania, Goias, Brazil and considered the role of several social determinants. A questionnaire examining the characteristics of the children and their families was administered to the primary caregiver during home visits. In addition, children (approximately 6 years of age) had their height, weight, and tooth condition assessed. The primary ECC outcome was categorized as one of the following: caries experience (decayed, missing, filled tooth: "dmft" index > 0), active ECC (decayed teeth > 0), or active severe ECC (decayed teeth ≥ 6). Descriptive, bivariate and logistic regression analyses were conducted. The participants in the current study consisted of 269 caregiver-child dyads, 88.5% of whom were included in the Family Health Program. Caregivers were mostly mothers (67.7%), were 35.3 ± 10.0 years old on average and had 9.8 ± 3.1 years of formal education. The mean family income was 2.3 ± 1.5 times greater than the Brazilian minimum wage. On average, the children in the current study were 68.7 ± 3.8 months old. Of these, 51.7% were boys, 23.4% were overweight or obese, 45.0% had active ECC, and 17.1% had severe ECC. The average body mass index (BMI) of the children was 15.9 ± 2.2, and their dmft index was 2.5 ± 3.2. BMI was not associated with any of the three categories of dental caries (p > 0.05). In contrast, higher family incomes were significantly associated with the lack of caries experience in children (OR 1.22, 95%CI 1.01-1.50), but the mother's level of education was not significantly associated with ECC.

  11. Evaluation of anti-fatigue property of the extruded product of cereal grains mixed with Cordyceps militaris on mice.

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    Zhong, Lei; Zhao, Liyan; Yang, Fangmei; Yang, Wenjian; Sun, Yong; Hu, Qiuhui

    2017-01-01

    Fatigue is a biological phenomenon that involves a feeling of extreme physical or mental tiredness that could potentially cause some severe chronic diseases. Recently, diet therapy has provided a new alternative to alleviate physical fatigue. In our previous study, addition of Cordyceps militaris (C. militaris) into an extruded product was shown to provide high nutrition and unique flavors; however, little is known whether this product has some scientific evidence regarding anti-fatigue property. The purpose of this study was to evaluate the anti-fatigue effects of extruded products of cereal grains (EC) and EC mixed with C. militaris (ECC). The mice were divided into seven groups: one group received distilled water (Control group, n = 20), and the other groups received different dosages of EC (5, 10 and 20 g/kg body weight, n = 20 per group) or of ECC (5, 10 and 20 g/kg body weight, n = 20 per group) solution in water. All of the mice were administered with distilled water, EC or ECC continuously for 30 days by gavage and the anti-fatigue activity was evaluated using a weight-loaded swimming test, along with assessments of fatigue-related indicators. The mode of fighting fatigue was investigated by determining changes in exercise endurance and biochemical markers, including exhaustive swimming time, lactate dehydrogenase (LDH), blood lactic acid (BLA), creatine kinase (CK), blood urea nitrogen (BUN), malondialdehyde (MDA), glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), catalase (CAT), and hepatic and muscle glycogen levels. EC and ECC prolonged the swimming endurance time of mice compared to the control. The content of BLA at high dose of ECC group (20 g/kg) was significantly lower than that in the negative control group. CK, BUN and MDA levels were significantly reduced by treatment with EC and ECC compared to the negative control, while the low and middle dose of EC had no significant effect on MDA levels. Additionally, only the

  12. Satellite cell activity is differentially affected by contraction mode in human muscle following a work-matched bout of exercise

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    Robert D Hyldahl

    2014-12-01

    Full Text Available Optimal repair and adaptation of skeletal muscle is facilitated by resident stem cells (satellite cells. To understand how different exercise modes influence satellite cell dynamics, we measured satellite cell activity in conjunction with markers of muscle damage and inflammation in human skeletal muscle following a single work- and intensity-matched bout of eccentric (ECC or concentric contractions (CON. Participants completed a single bout of ECC (n=7 or CON (n=7 of the knee extensors. A muscle biopsy was obtained before and 24 h after exercise. Functional measures and immunohistochemical analyses were used to determine the extent of muscle damage and indices of satellite cell activity. Cytokine concentrations were measured using a multiplexed magnetic bead assay. Isokinetic peak torque decreased following ECC (p<0.05 but not CON. Greater histological staining of the damage marker Xin was observed in muscle samples of ECC vs CON. Tenasin C immunoreactivity increased 15 fold (P<0.01 following ECC and was unchanged following CON. The inflammatory cytokines interferon gamma-induced protein 10 (IP-10 and monocyte chemotactic protein 1 (MCP-1 increased pre- to post-ECC (4.26 ± 1.4 vs. 10.49 ± 5.8 pg/ml, and 3.06 ± 0.7 vs. 6.25 ± 4.6 pg/ml, respectively; p<0.05. There was no change in any cytokine post-CON. Satellite cell content increased 27% pre- to post-ECC (0.10 ± 0.031 vs. 0.127 ± 0.041, respectively; p<0.05. There was no change in satellite cell number in CON (0.099 ± 0.027 vs. 0.102 ± 0.029, respectively. There was no fiber type-specific satellite cell response following either exercise mode. ECC but not CON resulted in an increase in MyoD positive nuclei per myofiber pre- to post-exercise (p<0.05, but there was no change in MyoD DNA binding activity in either condition. In conclusion, ECC but not CON results in functional and histological evidence of muscle damage that is accompanied by increased satellite cell activity 24 h post-exercise.

  13. Prevalensi early childhood caries dan severe early childhood caries pada anak prasekolah di Gunung Anyar Surabaya (The prevalences of early childhood caries and severe early childhood caries in preschool children at Gunung Anyar Surabaya

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    Rahel Wahjuni Sutjipto

    2014-12-01

    Full Text Available Background: Early childhood caries (ECC is a serious health problem especially in young children. Frequent night time bottle feeding with milk and prolong breast-feeding are reported to be the possible cause. Purpose: The purpose of study was to determine the prevalence of ECC and severe early childhood caries (SECC in children at Preschool Gunung Anyar district Surabaya. Methods: The subjects were 65 children consist of children aged 6 months (5 children, 1 year (8 children, 2 years (24 children, and 3 years (28 children. All tooth surface is evaluated. If there was one or more DMFs, it was indicated as ECC, whereas if there was one or more DMFs on smooth surfaces, then indicated as SECC. Results: No caries has found in 6 months and 1 year old children. The higher prevalence of ECC and SECC is in 3 years old children. The most caries was found on mesial maxillary central incisors. Conclusion: This study shows that the prevalence of ECC in group of children aged 6 months - 3 years at Gunung Anyar Surabaya was 30.8 % , while the prevalence was 29.2 % SECC .Latar belakang: Karies anak usia dini merupakan masalah kesehatan yang serius terutama di kalangan anak-anak. Sering mengkonsumsi susu melalui botol pada malam hari dan pemberian ASI yang berkepanjangan dilaporkan sebagai faktor penyebab. Tujuan: Penelitian ini bertujuan untuk meneliti prevalensi ECC dan SECC pada kelompok anak di PAUD Gunung Anyar Surabaya. Metode: Subyek penelitian ini adalah 65 anak yang terdiri dari anak usia 6 bulan (5 anak, 1 tahun (8 anak, 2 tahun (24 anak, dan 3 tahun (28 anak. Semua permukaan gigi dievaluasi. Apabila terdapat 1 atau lebih dmfs, maka diindikasikan sebagai ECC, sedangkan apabila terdapat 1 atau lebih dmfs pada permukaan gigi yang halus, maka diindikasikan sebagai SECC. Hasil: Tidak ditemukan karies pada kelompok anak usia 6 bulan hingga 1 tahun. Prevalensi tinggi ECC dan SECC ditemukan pada kelompok anak usia 3 tahun. Area gigi yang paling sering terkena

  14. Association between iron status, iron deficiency anaemia, and severe early childhood caries: a case–control study

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    Schroth Robert J

    2013-02-01

    Full Text Available Abstract Background Severe tooth decay is known to affect the health and well-being of young children. However, little is known about the influence of Severe Early Childhood Caries (S-ECC on childhood nutritional status. The purpose of this study was to contrast ferritin and haemoglobin levels between preschoolers with S-ECC and caries-free controls. Methods Children were recruited as part of a larger case–control study examining differences in nutritional status between those with and without S-ECC. Preschoolers with S-ECC were recruited on the day of their dental surgery, while caries-free controls were recruited from the community. Parents completed a questionnaire and the child underwent venipuncture. The study was approved by the University’s Health Research Ethics Board. Statistics included descriptive, bivariate and logistic regression analyses. A p value ≤ .05 was significant. A total of 266 children were recruited; 144 with S-ECC and 122 caries-free. Results The mean age was 40.8 ± 14.1 months. The mean ferritin concentration for all children was 29.6 ± 17.9 μg/L while the mean haemoglobin level was 115.1 ± 10.1 g/L. Children with S-ECC were significantly more likely to have low ferritin (p=.033 and low haemoglobin levels (p>.001. Logistic regression analyses revealed that children with S-ECC were nearly twice as likely to have low ferritin levels and were over six times more likely to have iron deficiency anaemia than caries-free controls. Conclusions Children with S-ECC appear to be at significantly greater odds of having low ferritin status compared with caries-free children and also appear to have significantly lower haemoglobin levels than the caries-free control group. Children with S-ECC also appear to be at significantly greater odds for iron deficiency anaemia than cavity-free children.

  15. Salivary Cortisol as a Biomarker to Explore the Role of Maternal Stress in Early Childhood Caries

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    Sharat Chandra Pani

    2013-01-01

    Full Text Available Objective. To compare salivary cortisol levels of children with ECC and their mothers with those of caries free children from a similar sociodemographic cohort. Design. Sixty-four college-educated, working mothers from middle income families with no history of anxiety disorders and their first born children aged between 48 and 71 months were included in the study. Salivary cortisol levels were analyzed using electrochemiluminescence (ECL immunoassay. Statistical Analyses. Significance of difference between the cortisol levels of children with ECC and control children and of their mothers was analyzed using the Student’s t- test. The intraclass correlation coefficient was used to measure the significance of correlation of cortisol levels between the mother and the child with logistic regression to explore possible associations. Results. Mothers of children with ECC had significantly higher levels of salivary cortisol ( than mothers of caries free children. The salivary cortisol levels of children with ECC were significantly higher than caries free children (. A significant correlation existed between the salivary cortisol level of the mother and that of the child (. Conclusion. While salivary cortisol levels of the child seem to have a direct impact on the incidence of ECC, maternal stress seems to have an indirect effect.

  16. Prior muscular exercise affects cycling pattern.

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    Bieuzen, F; Hausswirth, C; Couturier, A; Brisswalter, J

    2008-05-01

    The aim of this study was to investigate the effect of concentric or eccentric fatiguing exercise on cycling pattern. Eleven well trained cyclists completed three sessions of cycling (control cycling test [CTRL], cycling following concentric [CC] or eccentric [ECC] knee contractions) at a mean power of 276.8 +/- 26.6 Watts. Concentric and eccentric knee contractions were performed at a load corresponding to 80 % of one repetition maximum with both legs. Before and after CTRL, CC or ECC knee contractions and after cycling, a maximal voluntary contraction (MVC) test was performed. Cardiorespiratory, mechanical and electromyographic activity (EMG) of the rectus femoris, vastus lateralis and biceps femoris muscles were recorded during cycling. A significant decrease in MVC values was observed after CC and ECC exercises and after the cycling. ECC exercise induced a significant decrease in EMG root mean square during MVC and a decrease in pedal rate during cycling. EMG values of the three muscles were significantly higher during cycling exercise following CC exercise when compared to CTRL. The main finding of this study was that a prior ECC exercise induces a greater neuromuscular fatigue than a CC exercise, and changes in cycling pattern.

  17. A comparison of cluster-based exposure variation and exposure variation analysis to detect muscular adaptation in the shoulder joint to subsequent sessions of eccentric exercise during computer work.

    Science.gov (United States)

    Samani, Afshin; Madeleine, Pascal

    2014-04-01

    The aim of this study was to compare the capability of a cluster-based exposure variation (C-EVA) with a conventional exposure variation analysis (EVA) to detect muscular adaptation in the shoulder joint to subsequent sessions of eccentric exercise (ECC). Eleven healthy subjects performed work with a computer mouse for 10min at three instants, i.e., before, immediately after, and 24h after ECC. The subjects repeated an identical procedure one week after the first session. Surface electromyography was recorded from descending and ascending part of the trapezius, deltoid anterior, and serratus anterior muscles. EVA and C-EVA were performed and their marginal distributions were extracted. A principal component analysis was applied to the marginal distributions of both EVA and C-EVA. Principal component difference was computed by subtraction of the corresponding principal components before the ECC from immediately after and 24h after the ECC. The first component extracted from C-EVA revealed an interactive effect between the sessions of ECC and instants whereas this effect was absent using the conventional EVA. The current study highlights the importance of a multivariate approach to analyze the potentially important changes in muscular activity in response to the repeated bout effect. Copyright © 2013 Elsevier Ltd. All rights reserved.

  18. Integration of 3D scale-based pseudo-enhancement correction and partial volume image segmentation for improving electronic colon cleansing in CT colonograpy.

    Science.gov (United States)

    Zhang, Hao; Li, Lihong; Zhu, Hongbin; Han, Hao; Song, Bowen; Liang, Zhengrong

    2014-01-01

    Orally administered tagging agents are usually used in CT colonography (CTC) to differentiate residual bowel content from native colonic structures. However, the high-density contrast agents tend to introduce pseudo-enhancement (PE) effect on neighboring soft tissues and elevate their observed CT attenuation value toward that of the tagged materials (TMs), which may result in an excessive electronic colon cleansing (ECC) since the pseudo-enhanced soft tissues are incorrectly identified as TMs. To address this issue, we integrated a 3D scale-based PE correction into our previous ECC pipeline based on the maximum a posteriori expectation-maximization partial volume (PV) segmentation. The newly proposed ECC scheme takes into account both the PE and PV effects that commonly appear in CTC images. We evaluated the new scheme on 40 patient CTC scans, both qualitatively through display of segmentation results, and quantitatively through radiologists' blind scoring (human observer) and computer-aided detection (CAD) of colon polyps (computer observer). Performance of the presented algorithm has shown consistent improvements over our previous ECC pipeline, especially for the detection of small polyps submerged in the contrast agents. The CAD results of polyp detection showed that 4 more submerged polyps were detected for our new ECC scheme over the previous one.

  19. Dermatoglyphics: A genetic marker of early childhood caries

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    C Anitha

    2014-01-01

    Full Text Available Background: It is an accepted fact that genetics plays an important role in determination of palmar dermatoglyphic patterns. Since caries is a multifactorial disease with the influence of genetic pattern, this study was undertaken to explore the possibility of dermatoglyphics as a noninvasive and early predictor of dental caries in children, so as to initiate preventive oral health measures at an early age. Materials and Methods: The study group comprised of 200 children aged between 4 and 5 years. The dmfs score was evaluated. The experimental group (Group 1, comprised of 100 children with early childhood caries (ECC with dmfs >5. The control group (Group 2 comprised of 100 children with dmfs score of 0. Results: An increased frequency of ulnar loops in caries-free children and whorls in children with ECC was observed. Low mean atd angle and low mean. Total ridge count was observed in the ECC group. Conclusion: There is definite variation in dermatoglyphics between the ECC and caries-free group, indicating that dermatoglyphic patterns can be used as a predictive tool for children with ECC.

  20. Prevalence of early childhood caries in non-fluoridated rural areas of Chile.

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    Gerardo Espinoza-Espinoza

    2016-12-01

    Full Text Available Introduction: Early Childhood Caries (ECC is a serious public health concern worldwide, especially in communities without water fluoridation. Objective: To determine the prevalence of ECC in 2 and 3 year old children attending rural daycare centers without access to water fluoridation. Methods: A cross-sectional study at community level was performed during 2012. The eligible population was composed of 2 and 3 year-old children from rural daycare centers located in non-fluoridated areas in regions La Araucanía, Los Ríos, and Los Lagos, Chile. Four calibrated examiners (ICC=0.83 measured the prevalence of dental caries based on criteria proposed by the WHO. Data were analyzed using chi-square test, t-test and logistic regression models. Results: The study sample consisted of 587 children; two-year-olds accounted for 53.32%, and 52.47% were female. Prevalence of ECC was 51.62% with a mean dmft index of 2.53. Region de la Araucanía had the highest ECC prevalence (52.79%. Variables that showed association were age, OHI-S and type of health insurance coverage (p<0.05. Conclusion: A high prevalence of ECC was found in areas with a non-fluoridated water supply.

  1. Managing Early Childhood Caries with Atraumatic Restorative Treatment and Topical Silver and Fluoride Agents

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    Duangporn Duangthip

    2017-10-01

    Full Text Available Early childhood caries (ECC is a significant global health problem affecting millions of preschool children worldwide. In general, preschool children from families with 20% of the lowest family incomes suffered about 80% of the ECC. Most, if not all, surveys indicated that the great majority of ECC was left untreated. Untreated caries progresses into the dental pulp, causing pain and infection. It can spread systemically, affecting a child’s growth, development and general health. Fundamental caries management is based on the conventional restorative approach. Because preschool children are too young to cope with lengthy dental treatment, they often receive dental treatment under general anaesthesia from a specialist dentist. However, treatment under general anaesthesia poses a life-threatening risk to young children. Moreover, there are few dentists in rural areas, where ECC is prevalent. Hence, conventional dental care is unaffordable, inaccessible or unavailable in many communities. However, studies showed that the atraumatic restorative treatment had a very good success rate in treating dentine caries in young children. Silver diamine fluoride is considered safe and effective in arresting dentine caries in primary teeth. The aim of this paper is to review and discuss updated evidence of these alternative approaches in order to manage cavitated ECC.

  2. A literature review of the relationship between breastfeeding and early childhood caries

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    Narjes Amiri TehraniZadeh

    2012-01-01

    Full Text Available Background and Aims: Improper feeding is one of the most important etiologic factors in early childhood caries (ECC. In some clinical trials, breast feeding (BF is mentioned as a causing factor in ECC. Results in this topic are different or even controversial. It is vital that all general advices given out are consistent with general health education messages. The aim of this study was to conduct a systematic review on the relationship between breast feeding and early childhood caries. Materials and Methods: Articles, guidelines, related books, and specific databases such as SID, PubMed, Scirus, Elsevier, American Association of Pediatric Dentistry (AAPD, American Association of Pediatrics (AAP and American Dental Association (ADA were searched for related topics cited since 1990. Early childhood caries definition, breast feeding and other variables such as sample size, study location and study design were analyzed.Results: According to data analysis, there was a lack of methodological consistency and inconsistent definitions of ECC and BF in the literature making it difficult to draw conclusions. Results about relationship between prolonged BF and ECC were inconclusive. There was a positive relationship between nocturnal BF and ECC. A history of BF did not have any effect on the caries incidence.Conclusion: Because of the role of breast feeding in children's health, it is important to inform the parents about the possibility of dental caries due to nocturnal breast feeding.

  3. Formation of Extrachromosomal Circular DNA from Long Terminal Repeats of Retrotransposons in Saccharomyces cerevisiae

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    Henrik D. Møller

    2016-02-01

    Full Text Available Extrachromosomal circular DNA (eccDNA derived from chromosomal Ty retrotransposons in yeast can be generated in multiple ways. Ty eccDNA can arise from the circularization of extrachromosomal linear DNA during the transpositional life cycle of retrotransposons, or from circularization of genomic Ty DNA. Circularization may happen through nonhomologous end-joining (NHEJ of long terminal repeats (LTRs flanking Ty elements, by Ty autointegration, or by LTR–LTR recombination. By performing an in-depth investigation of sequence reads stemming from Ty eccDNAs obtained from populations of Saccharomyces cerevisiae S288c, we find that eccDNAs predominantly correspond to full-length Ty1 elements. Analyses of sequence junctions reveal no signs of NHEJ or autointegration events. We detect recombination junctions that are consistent with yeast Ty eccDNAs being generated through recombination events within the genome. This opens the possibility that retrotransposable elements could move around in the genome without an RNA intermediate directly through DNA circularization.

  4. Development of Ecoefficient Engineered Cementitious Composites Using Supplementary Cementitious Materials as a Binder and Bottom Ash Aggregate as Fine Aggregate

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    Jin Wook Bang

    2015-01-01

    Full Text Available The purpose of this study is to develop ecoefficient engineered cementitious composites (ECC using supplementary cementitious materials (SCMs, including fly ash (FA and blast furnace slag (SL as a binder material. The cement content of the ECC mixtures was replaced by FA and SL with a replacement rate of 25%. In addition, the fine aggregate of the ECC was replaced by bottom ash aggregate (BA with a substitution rate of 10%, 20%, and 30%. The influences of ecofriendly aggregates on fresh concrete properties and on mechanical properties were experimentally investigated. The test results revealed that the substitution of SCMs has an advantageous effect on fresh concrete’s properties; however, the increased water absorption and the irregular shape of the BA can potentially affect the fresh concrete’s properties. The substitution of FA and SL in ECC led to an increase in frictional bond at the interface between PVA fibers and matrix, improved the fiber dispersion, and showed a tensile strain capacity ranging from 3.3% to 3.5%. It is suggested that the combination of SCMs (12.5% FA and 12.5% SL and the BA aggregate with the substitution rate of 10% can be effectively used in ECC preparation.

  5. Secure Antnet Routing Algorithm for Scalable Adhoc Networks Using Elliptic Curve Cryptography

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    V. Vijayalakshmi

    2007-01-01

    Full Text Available The secure end-to-end route discovery in the decentralized Mobile Adhoc Networks (MANETs should have to meet the requirements of prevention of DoS attacks on data traffic, should be adaptive and fault tolerant and must have high speed, low energy overhead and scalability for future development. In this research a secure routing using antnet mechanism and mutual authentication using Elliptic Curve Cryptography (ECC has been proposed to meet the above requirements. The common perception of public key cryptography is that it is not well suited for adhoc networks as they are very complex and slow. Against this popular belief, this research implements Elliptic Curve Cryptography -a public key cryptography scheme. ECC provides a similar level of security to conventional integer-based public-key algorithms, but with much shorter keys. Because of the shorter keys ECC algorithms run faster, require less space and consume less energy. These advantages make ECC a better choice of public key cryptography, especially for a resource constrained systems like MANETs. Using the antnet routing algorithm, the highly trustable route will be selected for data transfer and each Mobile Node (MN in MANET maintains the trust value of its one-hop neighbors. The mutual authentication between source and destination is done by master key exchange using Elliptic Curve Cryptography (ECC. v

  6. Outcome of phacoemulsification and extracapsular cataract extraction: A study in a district hospital in Malaysia.

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    Thevi, T; Reddy, S C; Shantakumar, C

    2014-01-01

    The aim of the study was to compare the outcomes of phacoemulsification (Phaco) and extracapsular cataract extraction (ECCE) in a district hospital setting. A retrospective analysis was done from the medical records of the patients who underwent Phaco and ECCE in Temerloh District Hospital, Pahang state between October 2009 and September 2010. The age, gender and ethnicity of the patients, intraoperative and postoperative complications, and the best corrected visual acuity at the last follow-up visit were noted. Statistical analysis was done using Stata Software Version 11.0. The results of the two procedures were compared. Out of the 179 cataract surgeries performed, 146 cases were Phaco and 33 were ECCE. In our study, 82 were men and 97 were women. The age of patients ranged from 39 to 82 years; majority of the patients (71.3%) were more than 60 years of age. There was a significant association between type of surgery and outcome of visual acuity (p = 0.001). There was no significant association between intraoperative complication and type of surgery (p = 0.166). Postoperative complications of the surgeries were not significantly different. Good visual outcome was noted in 80.1% of eyes operated by Phaco compared to 48.5% of eyes operated by ECCE procedure. Since the visual outcome was significantly better in Phaco compared to ECCE procedure (p = 0.001), we recommend that Phaco equipments should be supplied in the district hospitals with adequate facilities for performing intraocular surgery.

  7. Augmented lymphocyte expansion from solid tumors with engineered cells for costimulatory enhancement.

    Science.gov (United States)

    Friedman, Kevin M; Devillier, Laura E; Feldman, Steven A; Rosenberg, Steven A; Dudley, Mark E

    2011-01-01

    Treatment of patients with adoptive T-cell therapy requires expansion of unique tumor-infiltrating lymphocyte (TIL) cultures from single-cell suspensions processed from melanoma biopsies. Strategies which increase the expansion and reliability of TIL generation from tumor digests are necessary to improve access to TIL therapy. Previous studies have evaluated artificial antigen presenting cells for their antigen-specific and costimulatory properties. We investigated engineered cells for costimulatory enhancement (ECCE) consisting of K562 cells that express 4-1BBL in the absence of artificial antigen stimulation. ECCE accelerated TIL expansion and significantly improved TIL numbers (P=0.001) from single-cell melanoma suspensions. TIL generated with ECCE contain significantly more CD8CD62L and CD8CD27 T cells then comparable interleukin-2-expanded TIL and maintained antitumor reactivity. Moreover, ECCE improved TIL expansion from nonmelanoma-cell suspensions similar to that seen with melanoma tumors. These data demonstrate that the addition of ECCE to TIL production will enable the treatment of patients that are ineligible using current methods.

  8. Long-term change in intraocular pressure after extracapsular cataract extraction with posterior chamber intraocular lens implantation versus phacoemulsification with posterior chamber intraocular lens implantation in Indians.

    Science.gov (United States)

    Pal, Virendra K; Agrawal, Ajai; Suman, Suwarna; Pratap, V B

    2013-01-01

    The purpose of the study is to evaluate the long-term changes in intraocular pressure (IOP) after extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (PCIOL) implantation versus phacoemulsification with PCIOL implantation in otherwise normal cataract patients in India. The study was conducted in the Department of Ophthalmology, King George's Medical College, Lucknow between August 2000 and August 2001. One hundred and seventeen eyes of 115 patients were included in the study. 84 patients were randomly selected for ECCE with PCIOL implantation (ECCE group) and 31 patients were selected for phacoemulsification with PCIOL implantation (Phaco group). IOP was measured pre-operatively and post-operatively, from the 1(st) month to the 12(th) month. Statistical significance was indicated by P > 0.05. There was a mean fall in IOP of 2.70 mm Hg (19.74%) in the ECCE group and 2.74 mm Hg (20.57%) in the phaco group. The decrease in the mean post-operative IOP from baseline was statistically significant (P > 0.01) at the end of 2 months in both groups. There was no statistically significant difference in post-operative IOP at any visit between groups (P ECCE or phacoemulsification with IOL implantation. The lowering of IOP became statistically significant at about 2 months post-operatively, but became almost stable after the 4(th) month.

  9. Checking your SOCCs and feet: the molecular mechanisms of Ca2+ entry in skeletal muscle.

    Science.gov (United States)

    Dirksen, Robert T

    2009-07-01

    It has long been known that skeletal muscle contraction persists in the absence of extracellular Ca(2+). Nevertheless, recent evidence indicates that multiple distinct Ca(2+) entry pathways exist in skeletal muscle: one active at negative potentials that requires store depletion (store-operated calcium entry or SOCE) and a second that is independent of store depletion and is activated by depolarization (excitation-coupled calcium entry or ECCE). This review highlights recent findings regarding the molecular identity, subcellular localization, and inter-relationship between SOCE and ECCE in skeletal muscle. The respective roles of ryanodine receptors (RyRs), dihydropyridine receptors (DHPRs), inositol-1,4,5-trisphosphate receptors (IP(3)Rs), canonical transient receptor potential channels (TRPCs), STIM1 Ca(2+) sensor proteins, and Orai1 Ca(2+) permeable channels in mediating SOCE and ECCE in skeletal muscle are discussed. Differences between SOCE and ECCE in skeletal muscle with Ca(2+) entry mechanisms in non-excitable cells are also reviewed. Finally, potential physiological roles for SOCE and ECCE in skeletal muscle development and function, as well as other currently unanswered questions and controversies in the field are also considered.

  10. Cost-effectiveness analysis of cataract surgery with intraocular lens implantation: extracapsular cataract extraction versus phacoemulsification

    Directory of Open Access Journals (Sweden)

    Mohd R.A. Manaf

    2007-03-01

    Full Text Available A randomized single blinded clinical trial to compare the cost-effectiveness of cataract surgery between extracapsular cataract extraction (ECCE and phacoemulsification (PEA was conducted at Hospital Universiti Kebangsaan Malaysia (HUKM from March 2000 until August 2001. The cost of a cataract surgery incurred by hospital, patients and households were calculated preoperatively, one week, two months (for both techniques and six months (for ECCE only. Effectiveness of cataract surgery was assessed using Visual Function 14 (VF-14, quality of life measurement specifically for vision. The cost analysis results from each 50 subjects of ECCE and PEA group showed that average cost for one ECCE after six months post-operation is USD 458 (± USD 72 and for PEA is USD 528 (± USD 125. VF-14 score showed a significant increased after a week, two months and six months post-operation compared to the score before operation for both techniques (p<0.001. However, there was no significant difference between them (p = 0.225. This study indicated that ECCE is more cost effective compared to PEA with cost per one unit increment of VF-14 score of USD 14 compared to USD 20 for PEA. (Med J Indones 2007; 16:25-31 Keywords: cataract, cost-effectiveness, extracapsular cataract extraction, phacoemulsification, visual function 14

  11. Outcomes of manual extracapsular versus phacoemulsification cataract extraction by beginner resident surgeons.

    Science.gov (United States)

    Meeks, Landen A; Blomquist, Preston H; Sullivan, Brian R

    2013-11-01

    To evaluate the safety and efficacy of phacoemulsification cataract extraction and manual extracapsular cataract extraction (ECCE) performed by beginning resident surgeons. Dallas Veterans Affairs Medical Center, Dallas, Texas, USA. Retrospective cohort study. A review was performed of each resident's series of initial cataract surgery procedures as a late first-year or second-year resident. Data were collected for cases performed over almost a 6-year period during which initially the first primary surgeon cases were ECCE and later, the first primary surgeon cases were phacoemulsification. For each case, the following data were gathered: technique of cataract extraction, laterality, resident, vitreous loss or dropped nucleus, placement of posterior chamber intraocular lens (IOL), and need for reoperation within 90 days of surgery. Complications occurred in 6 (2.5%) of 244 cases in which phacoemulsification was performed by a beginner resident primary surgeon and in 7 (4.1%) of 172 cases in which ECCE was used (P=.40). Posterior chamber IOLs were placed in all but 2 phacoemulsification cases and 4 ECCE cases (P=.24). Moreover, 3 cases in the phacoemulsification group and 1 case in the ECCE group required a reoperation within 90 days (P=.65). Phacoemulsification cataract extraction can be taught safely and effectively to residents with no cataract surgery experience as a primary surgeon. Copyright © 2013 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  12. Prevalence and determinant of early childhood caries among the children attending the Anganwadis of Wardha district, India

    Directory of Open Access Journals (Sweden)

    Abhay M Gaidhane

    2013-01-01

    Materials and Methods: Community-based cross-sectional study among the selected Anganwadis children of 2-5 years of Wardha district. Result: A total 330 subjects, 105 children were found to be having ECC, 47 (30.92% males and 58 (32.58% females. Total 215 children belonged to 43-60 months age group. Out of these, 72 (33.48% children were having ECC. A significant association was found between the history of bottle-feeding and ECC (P = 0.0218. Prevalence of ECC was more among those who were bottle-fed than those who were not bottle-fed. Conclusion: Future health promotion and education programs in Anganwadis should include oral health issues and the risk factors for ECC, and its consequences should be addressed. Public-funded oral health program should be started and targeted at children from lower socioeconomic status. Effective strategies should be developed to promote use of brush and paste for cleaning teeth and discouraging inappropriate bottle-feeding, discouraging on demand consumption of chocolates and sugars.

  13. Increased enamel hypoplasia and very low birthweight infants.

    Science.gov (United States)

    Nelson, S; Albert, J M; Geng, C; Curtan, S; Lang, K; Miadich, S; Heima, M; Malik, A; Ferretti, G; Eggertsson, H; Slayton, R L; Milgrom, P

    2013-09-01

    Birth cohort studies of developmental defects of enamel (DDE) and early childhood caries (ECC) in very low birthweight (VLBW) and normal birthweight (NBW) infants are rare. In this birth cohort of 234 VLBW and 234 NBW infants, we report the incidence of ECC and DDE at 8 and 18-20 mos of corrected age. Infant medical and maternal socio-demographic data were abstracted from medical records at birth. Dental assessments for ECC and DDE (enamel hypoplasia, demarcated and diffuse opacities) were completed at 8 and 18-20 mos. The incidence of hypoplasia was significantly higher in VLBW compared with NBW infants (8 mos, 19% vs. 2%; 18 mos, 31% vs. 8%). The incidence of ECC (International Caries Detection and Assessment System: ICDAS ≥ 2) was 1.4% (8 mos) and 12% (18-20 mos) and was similar between the VLBW and NBW groups. At both ages, using a beta-binomial regression model to control for potential confounders (maternal and infant characteristics), we found increased risk for enamel hypoplasia among the VLBW infants compared with the NBW infants. African Americans had a lower risk for enamel hypoplasia at 18-20 mos. The VLBW infants should be monitored for ECC due to the presence of enamel hypoplasia.

  14. Nutrient accumulation and biomass production of alfafa after soil amendment with silicates

    Directory of Open Access Journals (Sweden)

    Angélica Cristina Fernandes Deus

    2014-06-01

    Full Text Available Studies on the use of silicate correctives in agriculture show that they have great potential to improve soil chemical characteristics, however, little information is available on the reactivity rates of their particle-size fractions. This study investigated whether the reactivity rates obtained experimentally could be considered in the calculation of ECC (effective calcium carbonate for soil liming, promoting adequate development of alfalfa plants. Six treatments were evaluated in the experiment, consisting of two slag types applied in two rates. The experimental ECC was used to calculate one of the rates and the ECC determined in the laboratory was used to calculate the other. Rates of limestone and wollastonite were based on the ECC determined in laboratory. The rates of each soil acidity corretive were calculated to increase the base saturation to 80%. The treatments were applied to a Rhodic Hapludox and an Alfisol Ferrudalfs. The methods for ECC determination established for lime can be applied to steel slag. The application of slag corrected soil acidity with consequent accumulation of Ca, P, and Si in alfalfa, favoring DM production.

  15. Isolation, Characterization, and Identification of Biological Control Agent for Potato Soft Rot in Bangladesh

    Directory of Open Access Journals (Sweden)

    M. M. Rahman

    2012-01-01

    Full Text Available A total of 91 isolates of probable antagonistic bacteria of potato soft rot bacterium Erwinia carotovora subsp. carotovora (Ecc were extracted from rhizospheres and endophytes of various crop plants, different soil varieties, and atmospheres in the potato farming areas of Bangladesh. Antibacterial activity of the isolated probable antagonistic bacteria was tested in vitro against the previously identified most common and most virulent soft rot causing bacterial strain Ecc P-138. Only two isolates E-45 and E-65 significantly inhibited the in vitro growth of Ecc P-138. Physiological, biochemical, and carbon source utilization tests identified isolate E-65 as a member of the genus Bacillus and the isolate E-45 as Lactobacillus sp. The stronger antagonistic activity against Ecc P-138 was found in E-65 in vitro screening and storage potatoes. E-65 reduced the soft rot infection to 22-week storage potatoes of different varieties by 32.5–62.5% in model experiment, demonstrating its strong potential to be used as an effective biological control agent for the major pectolytic bacteria Ecc. The highest (62.5% antagonistic effect of E-65 was observed in the Granola and the lowest (32.7% of that was found in the Cardinal varieties of the Bangladeshi potatoes. The findings suggest that isolate E-65 could be exploited as a biocontrol agent for potato tubers.

  16. 2nd Euro-China Conference on Intelligent Data Analysis and Applications

    CERN Document Server

    Jiang, Xin; Snášel, Václav; Pan, Jeng-Shyang

    2015-01-01

    This volume of Advances in Intelligent Systems and Computing contains accepted papers presented in the main track of ECC 2015, the Second Euro-China Conference on Intelligent Data Analysis and Applications. The aim of ECC is to provide an internationally respected forum for scientific research in the broad area of intelligent data analysis, computational intelligence, signal processing, and all associated applications of AIs. The second edition of ECC was organized jointly by VSB - Technical University of Ostrava, Czech Republic, and Fujian University of Technology, Fuzhou, China. The conference, organized under the patronage of Mr. Miroslav Novak, President of the Moravian-Silesian Region, took place in late June and early July 2015 in the Campus of the VSB - Technical University of Ostrava, Czech Republic.

  17. A review: Self-healing in cementitious materials and engineered cementitious composite as a self-healing material

    DEFF Research Database (Denmark)

    Wu, Min; Johannesson, Björn; Geiker, Mette

    2012-01-01

    Cementitious Composite (ECC) is a new type of cement-based materials, which has unique properties compared with traditional cementitious materials. Further, a summary about the research status of self-healing on ECC is given. It shows that ECC bears great potential in realizing effective self-healing due......Cementitious materials are the most widely used building materials all over the word. However, deterioration is inevitable even since the very beginning of the service life, then maintenance and repair work, which are often labor- and capital-intensive, would be followed. Thus, self-healing...... of the affected cementitious materials is of great importance. Self-healing phenomenon in cementitious materials has been noticed and been studying for a long time. The possible mechanisms for self-healing phenomenon in cementitious materials, which are summarized based on substantial experimental studies...

  18. Utilization of calcium carbonate particles from eggshell waste as coating pigments for ink-jet printing paper.

    Science.gov (United States)

    Yoo, Sukjoon; Hsieh, Jeffery S; Zou, Peter; Kokoszka, John

    2009-12-01

    The effective treatment and utilization of biowaste have been emphasized in our society for environmental and economic concerns. Recently, the eggshell waste in the poultry industry has been highlighted because of its reclamation potential. This study presents an economical treatment process to recover useful bioproducts from eggshell waste and their utilization in commercial products. We developed the dissolved air floatation (DAF) separation unit, which successfully recovered 96% of eggshell membrane and 99% of eggshell calcium carbonate (ECC) particles from eggshell waste within 2 h of operation. The recovered ECC particles were utilized as coating pigments for ink-jet printing paper and their impact on the ink density and paper gloss were investigated. The addition of the ECC particles as coating pigments enhances the optical density of cyan, magenta and yellow inks while decreasing the black ink density and the gloss of the coated paper.

  19. Study on the interaction between gliadins and a coumarin as molecular model system of the gliadins-anthocyanidins complexes.

    Science.gov (United States)

    Tozzi, Silvia; Zanna, Nicola; Taddei, Paola

    2013-12-15

    To clarify the conformational changes of gliadins (Glia) upon complexation with anthocyanidins (in particular cyanidin, Cya), the interaction of Glia with a coumarin derivative (3-ethoxycarbonylcoumarin, 3-EcC), having a benzocondensed structure similar to that of Cya, has been investigated by NMR, IR, and Raman spectroscopy under acidic and neutral conditions. Raman spectra showed that both molecules produce a similar effect on the Glia structure, i.e. an increase in the α-helix conformation and a decrease in β-sheet and β-turns content. In the presence of both molecules, this effect is more marked; the spectroscopic results showed that both Cya and 3-EcC interact with Glia and 3-EcC favors the complex formation with Glia. The results obtained in this study provide new insights into anthocyanidins-Glia interactions and may have relevance to human health, in the field of the attempts to modify gluten proteins to decrease allergen immunoreactivity.

  20. Degradation and Failure Characteristics of NPP Containment Protective Coating Systems

    Energy Technology Data Exchange (ETDEWEB)

    Sindelar, R.L.

    2001-04-10

    Nuclear power plants (NPPs) must ensure that the emergency core cooling system (ECCS) or safety-related containment spray system (CSS) remains capable of performing its design safety function throughout the life of the plant. This requires ensuring that long-term core cooling can be maintained following a postulated loss-of-coolant accident (LOCA). Adequate safety operation can be impaired if the protective coatings which have been applied to the concrete and steel structures within the primary containment fail, producing transportable debris which could then accumulate on BWR ECCS suction strainers or PWR ECCS sump debris screens located within the containment. This document will present the data collected during the investigation of coating specimens from plants.

  1. Progress in Early Childhood Caries and Opportunities in Research, Policy, and Clinical Management

    DEFF Research Database (Denmark)

    Garcia, Raul; Borrelli, Belinda; Dhar, Vineet;

    2015-01-01

    The 2014 Early Childhood Caries Conference encompassed evidence-based reviews on the state of the science regarding early childhood carries (ECC) epidemiology, etiology, prevention, and disease management. The purpose of this paper was to discuss the work presented at the conference and identify...... opportunities in research, policy, and clinical management that may improve early childhood caries outcomes and lower costs of care. While great progress has been made since the 1997 ECC Conference, there remains a paucity of high-quality evidence from randomized controlled trials on what are the most effective...... to identify preschool children at risk for caries. Fluoridated toothpaste and fluoride varnish currently are the most effective chemotherapeutic strategies to prevent ECC. Motivational interviewing, a form of patient-centered counseling, is effective for motivating oral health behaviors and shows promise...

  2. Utility based Power Control with FEC in Hexagonally deployed WSN

    Directory of Open Access Journals (Sweden)

    Rajendran Valli

    2012-03-01

    Full Text Available The fundamental component of resource management in Wireless Sensor Network (WSN is transmitter power control since they are miniature battery powered devices. An efficient power control technique is essential to maintain reliable communication links in WSN and to maintain the battery life of the sensor node and in turn the sensor network. Error control coding (ECC schemes can improve the system performance and has an impact on energy consumption. This paper analyses a game theoretic model with pricing for power control in a sensor network considering ECC for random, square, triangular and hexagonal deployment schemes. The performance of the proposed power control scheme with RS and MIDRS code for WSN is evaluated in terms of utility, and energy consumption. Simulation results show that, for hexagonal deployment scheme, with the inclusion of ECC, the transmitting power of the nodes is reduced thereby saving energy and increasing the network lifetime

  3. Relativistic extended coupled cluster method for magnetic hyperfine structure constant

    CERN Document Server

    Sasmal, Sudip; Nayak, Malaya K; Vaval, Nayana; Pal, Sourav

    2015-01-01

    This article deals with the general implementation of 4-component spinor relativistic extended coupled cluster (ECC) method to calculate first order property of atoms and molecules in their open-shell ground state configuration. The implemented relativistic ECC is employed to calculate hyperfine structure (HFS) constant of alkali metals (Li, Na, K, Rb and Cs), singly charged alkaline earth metal atoms (Be+, Mg+, Ca+ and Sr+) and molecules (BeH, MgF and CaH). We have compared our ECC results with the calculations based on restricted active space configuration interaction (RAS-CI) method. Our results are in better agreement with the available experimental values than those of the RAS-CI values.

  4. A Review on Elliptic Curve Cryptography for Embedded Systems

    CERN Document Server

    Afreen, Rahat

    2011-01-01

    Importance of Elliptic Curves in Cryptography was independently proposed by Neal Koblitz and Victor Miller in 1985.Since then, Elliptic curve cryptography or ECC has evolved as a vast field for public key cryptography (PKC) systems. In PKC system, we use separate keys to encode and decode the data. Since one of the keys is distributed publicly in PKC systems, the strength of security depends on large key size. The mathematical problems of prime factorization and discrete logarithm are previously used in PKC systems. ECC has proved to provide same level of security with relatively small key sizes. The research in the field of ECC is mostly focused on its implementation on application specific systems. Such systems have restricted resources like storage, processing speed and domain specific CPU architecture.

  5. Practice parameters for early colon cancer management: Italian Society of Colorectal Surgery (Società Italiana di Chirurgia Colo-Rettale; SICCR) guidelines.

    Science.gov (United States)

    Bianco, F; Arezzo, A; Agresta, F; Coco, C; Faletti, R; Krivocapic, Z; Rotondano, G; Santoro, G A; Vettoretto, N; De Franciscis, S; Belli, A; Romano, G M

    2015-10-01

    Early colon cancer (ECC) has been defined as a carcinoma with invasion limited to the submucosa regardless of lymph node status and according to the Royal College of Pathologists as TNM stage T1 NX M0. As the potential risk of lymph node metastasis ranges from 6 to 17% and the preoperative assessment of lymph node metastasis is not reliable, the management of ECC is still controversial, varying from endoscopic to radical resection. A meeting on recent advances on the management of colorectal polyps endorsed by the Italian Society of Colorectal Surgery (SICCR) took place in April 2014, in Genoa (Italy). Based on this material the SICCR decided to issue guidelines updating the evidence and to write a position statement paper in order to define the diagnostic and therapeutic strategy for ECC treatment in context of the Italian healthcare system.

  6. Magnetic resonance imaging and electromyography as indexes of muscle function

    Science.gov (United States)

    Adams, Gregory R.; Duvoisin, Marc R.; Dudley, Gary A.

    1992-01-01

    A hypothesis is tested that exercise-induced magnetic resonance (MR) contrast shifts would relate to electromyography (EMG) amplitude if both measures reflect muscle use during exercise. Both magnetic resonance images (MRI) and EMG data were obtained for separate eccentric (ECC) and cocentric (CON) exercise of increasing intensity for seven subjects 30-32 yr old. CON and ECC actions caused increased integrated EMG (IEMG) and T2 values which were strongly related with relative resistance. The rate of increase and absolute value of both T2 and IEMG were found to be greater for CON than for ECC actions. For both actions IEMG and T2 were correlated. Data obtained suggest that surface IEMG accurately reflects the contractile behavior of muscle and exercise-induced increases in MRI T2 values reflect certain processes that scale with muscle use.

  7. Electron/pion separation with an Emulsion Cloud Chamber by using a Neural Network

    CERN Document Server

    Arrabito, L.; Bozza, C.; Buontempo, S.; Caffari, Y.; Consiglio, L.; Cozzi, M.; D'Ambrosio, N.; De Lellis, G.; De Serio, M.; Di Capua, F.; Di Ferdinando, D.; Di Marco, Natalia; Ereditato, A.; Esposito, L.S.; Gagnebin, S.; Giacomelli, G.; Giorgini, M.; Grella, G.; Hauger, M.; Ieva, M.; Janicsko Csathy, J.; Juget, F.; Kreslo, I.; Laktineh, I.; Longhin, A.; Mandrioli, G.; Marotta, A.; Marteau, J.; Migliozzi, P.; Monacelli, Piero; Moser, U.; Muciaccia, M.T.; Pastore, A.; Patrizii, L.; Pistillo, C.; Pozzato, M.; Romano, G.; Rosa, G.; Russo, A.; Savvinov, N.; Schembri, A.; Scotto Lavina, L.; Simone, S.; Sioli, M.; Sirignano, C.; Sirri, G.; Strolin, Paolo Emilio; Tioukov, V.

    2007-01-01

    We have studied the performance of a new algorithm for electron/pion separation in an Emulsion Cloud Chamber (ECC) made of lead and nuclear emulsion films. The software for separation consists of two parts: a shower reconstruction algorithm and a Neural Network that assigns to each reconstructed shower the probability to be an electron or a pion. The performance has been studied for the ECC of the OPERA experiment [1]. The $e/\\pi$ separation algorithm has been optimized by using a detailed Monte Carlo simulation of the ECC and tested on real data taken at CERN (pion beams) and at DESY (electron beams). The algorithm allows to achieve a 90% electron identification efficiency with a pion misidentification smaller than 1% for energies higher than 2 GeV.

  8. Strength Correlation and Prediction of Engineered Cementitious Composites with Microwave Properties

    Directory of Open Access Journals (Sweden)

    Kwok L. Chung

    2016-12-01

    Full Text Available This paper presents the results of microwave and mechanical measurements of engineered cementitious composites (ECCs using a nondestructive microwave near-field detecting technique. The objective of this research is to investigate the correlations between effective conductance and compressive strength of ECCs at various curing ages under the influence of different initial water contents. Parallel measurements and regression analysis on compressive strength and microwave conductance were undertaken. It is shown that the strength evolution of ECCs can be accurately modeled and predicted by using microwave conductance at the early ages using bi-exponential functions. Compressive strength grows as a function of decreasing effective conductance, whereas the regression coefficients of the correlation models have a linear variation with water-to-binder ratios. These findings have highlighted the effectiveness of the microwave technique in detecting the variation of liquid phase morphology and pore structure.

  9. DEVELOPMENT OF HAZARDOUS SLUDGE SIMULANTS FOR ENHANCED CHEMICAL CLEANING TESTS

    Energy Technology Data Exchange (ETDEWEB)

    Eibling, R.

    2010-04-12

    An Enhanced Chemical Cleaning (ECC) process is being developed by Savannah River Remediation (SRR) to aid in Savannah River Site (SRS) High-Level Waste (HLW) tank closure. After bulk waste removal, the ECC process can be used to dissolve and remove much of the remaining sludge from HLW tanks. The ECC process uses dilute oxalic acid (1 wt %) with in-line pH monitoring and control. The resulting oxalate is decomposed through hydroxylation using an Advanced Oxidation Process (AOP). Minimizing the amount of oxalic acid used for dissolution and the subsequent oxidative destruction of oxalic acid will minimize the potential for downstream impacts. Initial efficacy tests by AREVA demonstrated that previous tank heel simulants could be dissolved using dilute oxalic acid. The oxalate could be decomposed by an AOP that utilized ozone and ultraviolet (UV) light, and the resultant metal oxides and hydroxides could be separated out of the process.

  10. The Accumulative Effect of Concentric-Biased and Eccentric-Biased Exercise on Cardiorespiratory and Metabolic Responses to Subsequent Low-Intensity Exercise: A Preliminary Study.

    Science.gov (United States)

    Gavin, James Peter; Myers, Stephen; Willems, Mark Elisabeth Theodorus

    2015-12-22

    The study investigated the accumulative effect of concentric-biased and eccentric-biased exercise on cardiorespiratory, metabolic and neuromuscular responses to low-intensity exercise performed hours later. Fourteen young men cycled at low-intensity (~60 rpm at 50% maximal oxygen uptake) for 10 min before, and 12 h after: concentric-biased, single-leg cycling exercise (CON) (performed ~19:30 h) and eccentric-biased, double-leg knee extension exercise (ECC) (~06:30 h the following morning). Respiratory measures were sampled breath-by-breath, with oxidation values derived from stoichiometry equations. Knee extensor neuromuscular function was assessed before and after CON and ECC. Cardiorespiratory responses during low-intensity cycling were unchanged by accumulative CON and ECC. The RER was lower during low-intensity exercise 12 h after CON and ECC (0.88 ± 0.08), when compared to baseline (0.92 ± 0.09; p = 0.02). Fat oxidation increased from baseline (0.24 ± 0.2 g·min(-1)) to 12 h after CON and ECC (0.39 ± 0.2 g·min(-1); p = 0.01). Carbohydrate oxidation decreased from baseline (1.59 ± 0.4 g·min(-1)) to 12 h after CON and ECC (1.36 ± 0.4 g·min(-1); p = 0.03). These were accompanied by knee extensor force loss (right leg: -11.6%, p eccentric-biased exercise led to increased fat oxidation and decreased carbohydrate oxidation, without impairing cardiorespiration, during low-intensity cycling. An accumulation of fatiguing and damaging exercise increases fat utilisation during low intensity exercise performed as little as 12 h later.

  11. Effects of blood flow restricted low-intensity concentric or eccentric training on muscle size and strength.

    Directory of Open Access Journals (Sweden)

    Tomohiro Yasuda

    Full Text Available We investigated the acute and chronic effects of low-intensity concentric or eccentric resistance training with blood flow restriction (BFR on muscle size and strength. Ten young men performed 30% of concentric one repetition maximal dumbbell curl exercise (four sets, total 75 reps 3 days/week for 6 weeks. One arm was randomly chosen for concentric BFR (CON-BFR exercise only and the other arm performed eccentric BFR (ECC-BFR exercise only at the same exercise load. During the exercise session, iEMG for biceps brachii muscles increased progressively during CON-BFR, which was greater (p<0.05 than that of the ECC-BFR. Immediately after the exercise, muscle thickness (MTH of the elbow flexors acutely increased (p<0.01 with both CON-BFR and ECC-BFR, but was greater with CON-BFR (11.7% (p<0.01 than ECC-BFR (3.9% at 10-cm above the elbow joint. Following 6-weeks of training, MRI-measured muscle cross-sectional area (CSA at 10-cm position and mid-upper arm (12.0% and 10.6%, respectively as well as muscle volume (12.5% of the elbow flexors were increased (p<0.01 with CON-BFR. Increases in muscle CSA and volume were lower in ECC-BFR (5.1%, 0.8% and 2.9%, respectively than in the CON-BFR and only muscle CSA at 10-cm position increased significantly (p<0.05 after the training. Maximal voluntary isometric strength of elbow flexors was increased (p<0.05 in CON-BFR (8.6%, but not in ECC (3.8%. These results suggest that CON-BFR training leads to pronounced acute changes in muscle size, an index of muscle cell swelling, the response to which may be an important factor for promoting muscle hypertrophy with BFR resistance training.

  12. Pericyte response to contraction mode-specific resistance exercise training in human skeletal muscle.

    Science.gov (United States)

    Farup, Jean; De Lisio, Michael; Rahbek, Stine Klejs; Bjerre, Jonas; Vendelbo, Mikkel Holm; Boppart, Marni D; Vissing, Kristian

    2015-11-15

    Skeletal muscle satellite cells (SCs) are important for muscle repair and hypertrophy in response mechanical stimuli. Neuron-glial antigen 2-positive (NG2(+)) and alkaline phosphatase-positive (ALP(+)) pericytes may provide an alternative source of myogenic progenitors and/or secrete paracrine factors to induce Pax7(+) SC proliferation and differentiation. The purpose of this study was to investigate NG2(+) and ALP(+) cell quantity, as well as SC content and activation, in human skeletal muscle following prolonged concentric (Conc) or eccentric (Ecc) resistance training. Male subjects engaged in unilateral resistance training utilizing isolated Ecc or Conc contractions. After 12 wk, muscle biopsies were analyzed for NG2(+) and ALP(+) pericytes, total Pax7(+) SCs, activated SCs (Pax7(+)MyoD(+)), and differentiating myogenic cells (Pax7(-) MyoD(+)). NG2(+) cells localized to CD31(+) vessels and the majority coexpressed ALP. NG2(+) pericyte quantity decreased following both Conc and Ecc training (P < 0.05). ALP(+) pericyte quantity declined following Conc (P < 0.05) but not Ecc training. Conversely, total Pax7(+) SC content was elevated following Conc only (P < 0.001), while Pax7(+)MyoD(+) SC content was increased following Conc and Ecc (P < 0.001). Follow up analyses demonstrated that CD90(+) and platelet-derived growth factor receptor-α (PDGFRα)(+) mononuclear cell proliferation was also increased in response to both Conc and Ecc training (P < 0.01). In summary, resistance training results in a decline in pericyte quantity and an increase in mesenchymal progenitor cell proliferation, and these events likely influence SC pool expansion and increased activation observed posttraining.

  13. Dissolved organic carbon ameliorates the effects of UV radiation on a freshwater fish

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    Manek, Aditya K., E-mail: aditya.manek@usask.ca [Department of Biology, University of Saskatchewan, Saskatoon, S7N 5E2 SK (Canada); Ferrari, Maud C.O. [Department of Biomedical Sciences, WCVM, University of Saskatchewan, Saskatoon, S7N 5B4 SK (Canada); Chivers, Douglas P.; Niyogi, Som [Department of Biology, University of Saskatchewan, Saskatoon, S7N 5E2 SK (Canada)

    2014-08-15

    Anthropogenic activities over the past several decades have depleted stratospheric ozone, resulting in a global increase in ultraviolet radiation (UVR). Much of the negative effects of UVR in aquatic systems is minimized by dissolved organic carbon (DOC) which is known to attenuate UVR across the water column. The skin of many fishes contains large epidermal club cells (ECCs) that are known to play a role in innate immune responses and also release chemical alarm cues that warn other fishes of danger. This study investigated the effects of in vivo UVR exposure to fathead minnows (Pimephales promelas), under the influence of two sources of DOC: Sigma Aldrich humic acid, a coal based commercial source of DOC and Luther Marsh natural organic matter, a terrigenous source of DOC. Specifically, we examined ECC investment and physiological stress responses and found that fish exposed to high UVR, in the presence of either source of DOC, had higher ECC investment than fish exposed to high UVR only. Similarly, exposure to high UVR under either source of DOC, reduced cortisol levels relative to that in the high UVR only treatment. This indicates that DOC protects fish from physiological stress associated with UVR exposure and helps maintain production of ECC under conditions of UVR exposure. - Highlights: • We examined the combined effect of UV radiation and Dissolved Organic Carbon on fish. • Physiological stress response and epidermal club cell investment were measured. • Fish exposed to high UVR and DOC had higher ECC investment and reduced cortisol levels. • DOC plays a role in protecting fish from physiological stress and maintains ECC production.

  14. The Accumulative Effect of Concentric-Biased and Eccentric-Biased Exercise on Cardiorespiratory and Metabolic Responses to Subsequent Low-Intensity Exercise: A Preliminary Study

    Science.gov (United States)

    Gavin, James Peter; Myers, Stephen; Willems, Mark Elisabeth Theodorus

    2015-01-01

    The study investigated the accumulative effect of concentric-biased and eccentric-biased exercise on cardiorespiratory, metabolic and neuromuscular responses to low-intensity exercise performed hours later. Fourteen young men cycled at low-intensity (~60 rpm at 50% maximal oxygen uptake) for 10 min before, and 12 h after: concentric-biased, single-leg cycling exercise (CON) (performed ~19:30 h) and eccentric-biased, double-leg knee extension exercise (ECC) (~06:30 h the following morning). Respiratory measures were sampled breath-by-breath, with oxidation values derived from stoichiometry equations. Knee extensor neuromuscular function was assessed before and after CON and ECC. Cardiorespiratory responses during low-intensity cycling were unchanged by accumulative CON and ECC. The RER was lower during low-intensity exercise 12 h after CON and ECC (0.88 ± 0.08), when compared to baseline (0.92 ± 0.09; p = 0.02). Fat oxidation increased from baseline (0.24 ± 0.2 g·min−1) to 12 h after CON and ECC (0.39 ± 0.2 g·min−1; p = 0.01). Carbohydrate oxidation decreased from baseline (1.59 ± 0.4 g·min−1) to 12 h after CON and ECC (1.36 ± 0.4 g·min−1; p = 0.03). These were accompanied by knee extensor force loss (right leg: −11.6%, p eccentric-biased exercise led to increased fat oxidation and decreased carbohydrate oxidation, without impairing cardiorespiration, during low-intensity cycling. An accumulation of fatiguing and damaging exercise increases fat utilisation during low intensity exercise performed as little as 12 h later. PMID:26839613

  15. small range of motion with the same end-point

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    AG Fochi

    2016-08-01

    Full Text Available Several factors can affect the magnitude of eccentric exercise (ECC-induced muscle damage, but little is known regarding the effect of the range of motion (ROM in ECC-induced muscle damage. The purpose of this study was to investigate whether elbow flexor ECC with 120° of ROM (from 60° of elbow flexion until elbow full extension – 180° [120ROM] induces a greater magnitude of muscle damage compared with a protocol with 60° of ROM (120-180° of elbow flexion [60ROM]. Twelve healthy young men (age: 22 ± 3.1 years; height: 1.75 ± 0.05 m; body mass: 75.6 ± 13.6 kg performed the ECC with 120ROM and 60ROM using different arms in a random order separated by 2 weeks and were tested before and 24, 48, 72 and 96 h after ECC for maximal voluntary isometric contraction torque (MVC-ISO, ROM and muscle soreness. The 120ROM protocol showed greater changes and effect sizes (ES for MVC-ISO (-35%, ES: 1.97, ROM (-11.5°, ES: 1.27 and muscle soreness (19 mm, ES: 1.18 compared with the 60ROM protocol (-23%, ES: 0.93; -12%, ES: 0.56; 17°, ES: 0.63; 8 mm, ES: 1.07, respectively. In conclusion, ECC of the elbow flexors with 120° of ROM promotes a greater magnitude of muscle damage compared with a protocol with 60° of ROM, even when both protocols are performed at long muscle lengths.

  16. Small heat shock proteins translocate to the cytoskeleton in human skeletal muscle following eccentric exercise independently of phosphorylation.

    Science.gov (United States)

    Frankenberg, Noni T; Lamb, Graham D; Overgaard, Kristian; Murphy, Robyn M; Vissing, Kristian

    2014-06-01

    Small heat shock proteins (sHSPs) are a subgroup of the highly conserved family of HSPs that are stress inducible and confer resistance to cellular stress and injury. This study aimed to quantitatively examine whether type of contraction (concentric or eccentric) affects sHSPs, HSP27 and αB-crystallin, localization, and phosphorylation in human muscle. Vastus lateralis muscle biopsies from 11 healthy male volunteers were obtained pre- and 3 h, 24 h, and 7 days following concentric (CONC), eccentric (ECC1), and repeated bout eccentric (ECC2) exercise. No changes were apparent in a control group (n = 5) who performed no exercise. Eccentric exercise induced muscle damage, as evidenced by increased muscle force loss, perceived muscle soreness, and elevated plasma creatine kinase and myoglobin levels. Total HSP27 and αB-crystallin amounts did not change following any type of exercise. Following eccentric exercise (ECC1 and ECC2) phosphorylation of HSP27 at serine 15 (pHSP27-Ser15) was increased approximately 3- to 6-fold at 3 h, and pαB-crystallin-Ser59 increased ~10-fold at 3 h. Prior to exercise most of the sHSP and psHSP pools were present in the cytosolic compartment. Eccentric exercise resulted in partial redistribution of HSP27 (~23%) from the cytosol to the cytoskeletal fraction (~28% for pHSP27-Ser15 and ~7% for pHSP27-Ser82), with subsequent full reversal within 24 h. αB-crystallin also showed partial redistribution from the cytosolic to cytoskeletal fraction (~18% of total) 3 h post-ECC1, but not after ECC2. There was no redistribution or phosphorylation of sHSPs with CONC. Eccentric exercise results in increased sHSP phosphorylation and translocation to the cytoskeletal fraction, but the sHSP translocation is not dependent on their phosphorylation. Copyright © 2014 the American Physiological Society.

  17. Beclin 1 deficiency correlated with lymph node metastasis, predicts a distinct outcome in intrahepatic and extrahepatic cholangiocarcinoma.

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    Tian-Tian Wang

    Full Text Available Autophagy can be tumor suppressive as well as promotive in regulation of tumorigenesis and disease progression. Accordingly, the prognostic significance of autophagy key regulator Beclin 1 was varied among different tumors. Here, we detected the clinicopathological and prognostic effect of Beclin 1 in the subtypes of intrahepatic cholangiocarcinoma (ICC and extrahepatic cholangiocarcinoma (ECC. Beclin 1 expression level was detected by immunohistochemistry staining in 106 ICC and 74 ECC patients. We found that Beclin 1 was lowly expressed in 126 (70% cholangiocarcinoma patients, consist of 72 ICC and 54 ECC. Moreover, the cholangiocarcinoma patients with lymph node metastasis (N1 had a lower Beclin 1 level than that of N0 subgroup (P=0.012. However, we did not detect any correlations between Beclin 1 and other clinicopathological features, including tumor subtypes, vascular invasion, HBV infection, liver cirrhosis, cholecystolithiasis and TNM stage. Survival analysis showed that, compared with the high expression subset, Beclin 1 low expression was correlated with a poorer 3-year progression-free survival (PFS, 69.1% VS 46.8%, P=041 for cholangiocarcinoma. Importantly, our stratified univariate and multivariate analysis confirmed that Beclin 1 lowly expressed ICC had an inferior PFS as well as overall survival than ECC, particularly than that of Beclin 1 highly expressed ECC patients. Thus, our study demonstrated that Beclin 1low expression, correlated with lymph node metastasis, and might be a negative prognostic biomarker for cholangiocarcinoma. Combined Beclin 1 level with the anatomical location might lead to refined prognosis for the subtypes of ICC and ECC.

  18. Erwinia carotovora DsbA mutants: evidence for a periplasmic-stress signal transduction system affecting transcription of genes encoding secreted proteins.

    Science.gov (United States)

    Vincent-Sealy, L V; Thomas, J D; Commander, P; Salmond, G P

    1999-08-01

    The dsbA genes, which encode major periplasmic disulfide-bond-forming proteins, were isolated from Erwinia carotovora subsp. carotovora (Ecc) and Erwinia carotovora subsp. atroseptica (Eca), and the dsbC gene, encoding another periplasmic disulfide oxidoreductase was isolated from Ecc. All three genes were sequenced and mutants deficient in these genes were created by marker exchange mutagenesis. The Ecc mutants were severely affected in activity and secretion of pectate lyase, probably due to the absence of functional PelC, which is predicted to require disulfide bond formation to achieve its correct conformation prior to secretion across the outer membrane. Similarly, endopolygalacturonase, also predicted to possess disulfide bonds, displayed reduced activity. The major Ecc cellulase (CelV) does not contain cysteine residues and was still secreted in dsbA-deficient strains. This observation demonstrated unequivocally that the localization and activity of the individual components of the Out apparatus are independent of disulfide bond formation. Surprisingly, cellulase activity was shown to be increased approximately two- to threefold in the DsbA mutant. This phenomenon resulted from transcriptional up-regulation of celV gene expression. In contrast, transcription of both pelC and peh were down-regulated in dsbA-deficient strains when compared to the wild-type. Protease (Prt) activity and secretion were unaffected in the Ecc dsbA mutant. Prt activity was considerably reduced in the double dsbA dsbC mutant. However Prt was secreted normally in this strain. The Eca dsbA mutant was found to be non-motile, suggesting that disulfide bond formation is essential for motility in this strain. All of the dsb mutants showed reduced tissue maceration in planta. These results suggest that a feedback regulation system operates in Ecc. In this system, defects in periplasmic disulfide bond formation act as a signal which is relayed to the transcription machinery regulating gene

  19. Antenatal Health Care and Postnatal Dental Check-Ups Prevent Early Childhood Caries.

    Science.gov (United States)

    Nakai, Yukie; Mori, Yukako; Tamaoka, Izumi

    2016-01-01

    The first stage of early childhood caries (ECC) is infection by mutans streptococci, of which the primary infection source is the child's mother. Early intervention programs including antenatal and postnatal phases are effective for reducing ECC. This study was conducted to assess the respective effects of antenatal health care and postnatal care such as regular dental check-ups on reducing ECC among 3-year-old Japanese children. This nested case-control study of 155 three-year-old children (49.0% boys) was conducted at a dental clinic that provides collaborative health services with the Obstetrics and Gynecology Clinic, Okayama. Child characteristics and the mothers' antenatal data were collected retrospectively from the dental charts. They were divided into two groups: caries-free children (n = 77) and children without ECC (n = 78). Most of the children (81.9%) received regular check-ups with topical fluoride application. Most of the mothers reported morning sickness during pregnancy (81.3%), normal delivery (72.9%), and used antenatal health care (80.6%). Over half (55.5%) were primigravida. Adjusted odds ratio (AOR) and 95% confidential interval (95% CI) were computed to assess the strength of association using logistic regression analysis. Receiving antenatal health care (AOR, 3.27; 95% CI, 1.30-8.24) and child's having regular check-ups (AOR, 3.42; 95% CI, 1.35-8.69) were significantly associated with caries-free status among three-year old children. For ECC prevention, antenatal health care is as effective as regular check-ups up to three years of age. The results of this retrospective study demonstrate that maternal health education during pregnancy is effective for ECC prevention.

  20. Expression analysis of CD63 in salivary neutrophils and the increased level of Streptococcus mutans in severe early childhood caries

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    Muhammad Luthfi

    2015-06-01

    Full Text Available Background: Severe early childhood caries (S-ECC and decay exfoliation filling teeth (def-t >6 is a destructive disease that afflicts teeth, including maxillary anterior teeth. In Indonesia, the prevalence of this disease is still high, for instance in Semarang 2007, the rate reached 90.5% in urban areas and 95.9% in rural areas for early childhood caries which is caused by Streptococcus mutans (S. mutans. Neutrophils are effector cells of innate immunity which become the main component of the very first line of defense against microbes. Purpose: This study analyzed the effect caused by the change of CD63 expression on the surface of salivary neutrophils and the increased level of S. mutans in S-ECC. Method: This study employs observational analytic and cross sectional approach by using T test analysis technique for forty cases of early childhood that had been divided into two groups, first group of twenty children positively diagnosed as S-ECC and second group of twenty children negatively diagnosed as the control group. The sample’s result of gargling with 1.5% NaCl was used for neutrophils isolation and analysis function of salivary neutrophils phagocytosis by using flow cytometry test, while the sample of saliva was used to isolate S. mutans and calculate the level of S. mutans. Result: The expression of CD63+ salivary neutrophils in S-ECC was lower (2.32% ± 0.57 than in caries-free (2.67% ± 0.46, while the level of S. mutans showed that the level was not higher than in S-ECC (9.78 ± 2.22x105 CFU/ml compared to in caries-free (5.13 ± 1.86x105 CFU/ml. Conclusion: The low expression of CD63 in salivary neutrophils can lead to the increased level of S. mutans in S-ECC.

  1. Real-time measurement of free thrombin: evaluation of the usability of a new thrombin assay for coagulation monitoring during extracorporeal circulation.

    Science.gov (United States)

    Krajewski, Stefanie; Krauss, Sabrina; Kurz, Julia; Neumann, Bernd; Schlensak, Christian; Wendel, Hans P

    2014-03-01

    In patients undergoing cardiac surgery with heart-lung machine support, adequate anticoagulation to mitigate blood clotting caused by the artificial surfaces of the extracorporeal circulation (ECC) system is essential. These patients routinely receive heparin, whose effectiveness is monitored by measurements of the activated clotting time (ACT). However, ACT values only poorly correlate with the actual hemostatic status. The aim of our study was to evaluate the detection of free thrombin in heparinized human blood as a monitor of anticoagulation during ECC. Human whole blood was anticoagulated with different concentrations of heparin (0.75, 1, 2 or 3 IU/ml) and circulated in the Chandler-loop model for up to 240 min at 37 °C. Next to ACT, ECC-mediated changes in free active thrombin, prothrombin fragment 1+2 (F1+2) and thrombin-antithrombin-III (TAT) levels were measured before and during circulation. Platelet activation and cell count parameters were further investigated. Our study shows that detection of ECC-mediated changes in free thrombin is possible in blood anticoagulated with 0.75 or 1 IU/ml heparin, whereas no thrombin was detectable at higher heparin concentrations. Thrombin generation during 240 min of ECC is comparable to F 1+2 and TAT plasma levels during ECC. Thrombin is the key enzyme in the coagulation cascade and hence represents a promising marker for monitoring the coagulation status of patients. Although detection of free thrombin was not feasible at high heparin concentrations, the employed test represents an additional test to current laboratory methods investigating blood coagulation at low heparin concentrations. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Clinical evidence continuous medical education: a randomised educational trial of an open access e-learning program for transferring evidence-based information - ICEKUBE (Italian Clinical Evidence Knowledge Utilization Behaviour Evaluation) - study protocol.

    Science.gov (United States)

    Moja, Lorenzo; Moschetti, Ivan; Cinquini, Michela; Sala, Valeria; Compagnoni, Anna; Duca, Piergiorgio; Deligant, Christian; Manfrini, Roberto; Clivio, Luca; Satolli, Roberto; Addis, Antonio; Grimshaw, Jeremy M; Dri, Pietro; Liberati, Alessandro

    2008-07-17

    In an effort to ensure that all physicians have access to valid and reliable evidence on drug effectiveness, the Italian Drug Agency sponsored a free-access e-learning system, based on Clinical Evidence, called ECCE. Doctors have access to an electronic version and related clinical vignettes. Correct answers to the interactive vignettes provide Continuing Medical Education credits. The aims of this trial are to establish whether the e-learning program (ECCE) increases physicians' basic knowledge about common clinical scenarios, and whether ECCE is superior to the passive diffusion of information through the printed version of Clinical Evidence. All Italian doctors naïve to ECCE will be randomised to three groups. Group one will have access to ECCE for Clinical Evidence chapters and vignettes lot A and will provide control data for Clinical Evidence chapters and vignettes lot B; group two vice versa; group three will receive the concise printed version of Clinical Evidence. There are in fact two designs: a before and after pragmatic trial utilising a two by two incomplete block design (group one versus group two) and a classical design (group one and two versus group three). The primary outcome will be the retention of Clinical Evidence contents assessed from the scores for clinical vignettes selected from ECCE at least six months after the intervention. To avoid test-retest effects, we will randomly select vignettes out of lot A and lot B, avoiding repetitions. In order to preserve the comparability of lots, we will select vignettes with similar, optimal psychometric characteristics.

  3. Clinical evidence continuous medical education: a randomised educational trial of an open access e-learning program for transferring evidence-based information – ICEKUBE (Italian Clinical Evidence Knowledge Utilization Behaviour Evaluation) – study protocol

    Science.gov (United States)

    Moja, Lorenzo; Moschetti, Ivan; Cinquini, Michela; Sala, Valeria; Compagnoni, Anna; Duca, Piergiorgio; Deligant, Christian; Manfrini, Roberto; Clivio, Luca; Satolli, Roberto; Addis, Antonio; Grimshaw, Jeremy M; Dri, Pietro; Liberati, Alessandro

    2008-01-01

    Background In an effort to ensure that all physicians have access to valid and reliable evidence on drug effectiveness, the Italian Drug Agency sponsored a free-access e-learning system, based on Clinical Evidence, called ECCE. Doctors have access to an electronic version and related clinical vignettes. Correct answers to the interactive vignettes provide Continuing Medical Education credits. The aims of this trial are to establish whether the e-learning program (ECCE) increases physicians' basic knowledge about common clinical scenarios, and whether ECCE is superior to the passive diffusion of information through the printed version of Clinical Evidence. Design All Italian doctors naïve to ECCE will be randomised to three groups. Group one will have access to ECCE for Clinical Evidence chapters and vignettes lot A and will provide control data for Clinical Evidence chapters and vignettes lot B; group two vice versa; group three will receive the concise printed version of Clinical Evidence. There are in fact two designs: a before and after pragmatic trial utilising a two by two incomplete block design (group one versus group two) and a classical design (group one and two versus group three). The primary outcome will be the retention of Clinical Evidence contents assessed from the scores for clinical vignettes selected from ECCE at least six months after the intervention. To avoid test-retest effects, we will randomly select vignettes out of lot A and lot B, avoiding repetitions. In order to preserve the comparability of lots, we will select vignettes with similar, optimal psychometric characteristics. Trial registration ISRCTN27453314 PMID:18637189

  4. Investigation on the tear film stability after two types of cataract extractions

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    Qian-Qian Lan

    2016-02-01

    Full Text Available AIM:To investigate the tear film stability and dry eye after two types of cataract extractions by Oculus Keratograph. METHODS:Eighty-eight eyes in 67 patients with age related cataract were included in the study. Forty-six eyes in 35 patients underwent phacoemulsification(Phacocombined with intraocular lens implantation as Phaco group,while 42 eyes in 32 patients underwent non-phacoemulsification small incision extra-capsular cataract extraction(ECCEcombined with intraocular lens implantation as ECCE group. The first non-invasive tear break-up time(fNIBUT,the average non-invasive tear break-up time(aNIBUT,the tear meniscus height(TMHand the proportion of "dry eye" diagnosised in tear film stability grades before operations and at 1d,1 and 3mo after operations were recorded and analyzed. RESULTS:The fNIBUT, aNIBUT, TMH in Phaco group were higher than those in ECCE group,while the proportion of dry eye in Phaco group were lower than that in ECCE group at 1d postoperatively. The aNIBUT in Phaco group was still higher than that in ECCE group at 1mo postoperatively. The differences on these indicators between two groups were not statistically significant at 3mo postoperatively. Compared with that preoperatively, aNIBUT was reduced at 1d postoperatively, TMH was reduced at 1d and 1mo postoperatively, while the ratio of patients with abnormal TMH was increased 1mo postoperatively in Phaco group. The aNIBUT and TMH were reduced at 1d and 1mo postoperatively, the ratio of patients with abnormal TMH was increased at 1d and 3mo postoperatively, while the proportion of dry eye was increased at 1d and 1mo postoperatively in ECCE group. CONCLUSION:ECCE has more negative effects on the tear film stability than Phaco, which causes longer dry eye according to the Oculus Keratograph.

  5. ACTUAL-WASTE TESTING OF ULTRAVIOLET LIGHT TO AUGMENT THE ENHANCED CHEMICAL CLEANING OF SRS SLUDGE

    Energy Technology Data Exchange (ETDEWEB)

    Martino, C.; King, W.; Ketusky, E.

    2012-07-10

    In support of Savannah River Site (SRS) tank closure efforts, the Savannah River National Laboratory (SRNL) conducted Real Waste Testing (RWT) to evaluate Enhanced Chemical Cleaning (ECC), an alternative to the baseline 8 wt% oxalic acid (OA) chemical cleaning technology for tank sludge heel removal. ECC utilizes a more dilute OA solution (2 wt%) and an oxalate destruction technology using ozonolysis with or without the application of ultraviolet (UV) light. SRNL conducted tests of the ECC process using actual SRS waste material from Tanks 5F and 12H. The previous phase of testing involved testing of all phases of the ECC process (sludge dissolution, OA decomposition, product evaporation, and deposition tank storage) but did not involve the use of UV light in OA decomposition. The new phase of testing documented in this report focused on the use of UV light to assist OA decomposition, but involved only the OA decomposition and deposition tank portions of the process. Compared with the previous testing at analogous conditions without UV light, OA decomposition with the use of UV light generally reduced time required to reach the target of <100 mg/L oxalate. This effect was the most pronounced during the initial part of the decomposition batches, when pH was <4. For the later stages of each OA decomposition batch, the increase in OA decomposition rate with use of the UV light appeared to be minimal. Testing of the deposition tank storage of the ECC product resulted in analogous soluble concentrations regardless of the use or non-use of UV light in the ECC reactor.

  6. The relationship between child temperament and early childhood caries.

    Science.gov (United States)

    Quinonez, R; Santos, R G; Wilson, S; Cross, H

    2001-01-01

    Among the potential risk factors associated with nursing caries/baby bottle tooth decay--a subset of Early Childhood Caries (ECC)--is a "strong-tempered" behavioral style in the child. However, the few empirical studies that have investigated this description remain controversial. The research goal of this study was to operationalize the "strong-tempered" profile and investigate its association to parental feeding practices and ECC levels. In an observational-correlational study design, 58 children (ASA I), ages 18 to 70 months (M = 43 months, SD = 17), were reliably assessed for ECC levels by a clinical evaluator. A second evaluator, blind to ECC status, interviewed parents using a demographic survey, a feeding practices measure, and the EAS Temperament Survey for Children. Multiple regression analyses indicated that none of the four temperament factors (Emotionality, Activity, Sociability, and Shyness) significantly predicted duration of feeding habit defined as the length of time in months that the child breast or bottle fed, whichever lasted the longest. However, the combination of greater duration of feeding habit and higher levels of Shyness predicted all three measures of ECC: the presence or absence of caries (r2 = .19, P < .001), the number of carious teeth (r2 = .23, P < .001) and the number of carious surfaces (r2 = .21, P < .001). Furthermore, the addition of Native status significantly increased the predictive value of all of three models (r2 = .37, r2 = .43, r2 = .29, respectively, Ps < .0001). Temperament did not predict the duration of feeding habit but together, shyness and duration of feeding habit was associated with ECC.

  7. Nursing habits and early childhood caries in children attending Hospital University Science Malaysia (HUSM

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    Widowati Witjaksono

    2006-06-01

    Full Text Available The habit of nocturnal bottle or breast-feeding has been reported to be a potential cause for early childhood caries (ECC in very young children. The aim of this study was to determine the prevalence of ECC in children 2-5 years of age attending out patient clinic HUSM, in relation to the nursing habits. In this cross-sectional study, 90 children were randomly selected to examine their caries status using torch and disposable mirror. Data on mothers’ educational level, nursing habits and oral hygiene practices, were gather by using structured questionnaire. It has been found that 16.7% of subjects were caries free while 83.3% of them had caries with mean dmf score 6 (SD 5.3. With regard to nursing habits, 29% of subjects had breast-feeding alone, 16% had bottle-feeding alone and 55% had both breast and bottle-feeding. Ninety-three percent of children had been nursed beyond 14 months and 47% had been fed with liquids other than breast milk, infant formula or water. Twenty-seven percent of children were allowed to sleep with nursing bottle in mouth and 52% were allowed to sleep with breast nipple in the mouth which shows significantly associated with ECC (p = 0.03. Tooth brushing habit was reported for 91% of children using toothpaste. Mean age of the children (in months when the mothers started brushing the teeth was 19.1 (SD 10.8 and has significant association with ECC (p < 0.05. This study demonstrates that the habit of allowing infants to sleep with breast nipple in their mouth and the late start of tooth brushing are associated with prevalence of ECC. Educational programs for pregnant women and mothers of young children should be emphasized to enhance the knowledge and awareness of mothers in preventing ECC.

  8. Reduced muscle lengthening during eccentric contractions as a mechanism underpinning the repeated-bout effect.

    Science.gov (United States)

    Lau, Wing Yin; Blazevich, Anthony J; Newton, Michael J; Wu, Sam Shi Xuan; Nosaka, Kazunori

    2015-05-15

    This study investigated biceps brachii distal myotendinous junction (MTJ) displacement during maximal eccentric elbow flexor contractions to test the hypothesis that muscle length change would be smaller (less MTJ displacement) during the second than the first exercise bout. Ten untrained men performed two eccentric exercise bouts (ECC1 and ECC2) with the same arm consisting of 10 sets of six maximal isokinetic (60°/s) eccentric elbow flexor contractions separated by 4 wk. Biceps brachii distal MTJ displacement was assessed using B-mode ultrasonography, and changes in the displacement (muscle length change) from the start to the end of each contraction during each set and over 10 sets were compared between bouts by two-way repeated-measures ANOVA. Several indirect muscle damage markers were also measured and compared between bouts by two-way repeated-measures ANOVA. The magnitude of MTJ displacement (average of six contractions) increased from set 1 (8.2 ± 4.7 mm) to set 10 (16.4 ± 4.7 mm) during ECC1 (P < 0.05), but no significant changes over sets were evident during ECC2 (set 1: 8.5 ± 4.0 mm; set 10: 9.3 ± 3.1 mm). Changes in maximal voluntary isometric contraction strength, range of motion, muscle thickness, ultrasound echo intensity, serum creatine kinase activity, and muscle soreness (visual analog scale) were smaller (P < 0.05) following ECC2 than ECC1, showing less damage in the repeated bout. These results indicate that the magnitude of muscle lengthening was less during the second than the first eccentric exercise bout, which appears to be a mechanism underpinning the repeated-bout effect. Copyright © 2015 the American Physiological Society.

  9. Increased activity of the antioxidants systems modulate the oxidative stress in saliva of toddlers with early childhood caries.

    Science.gov (United States)

    Silva, Priscila Vieira da; Troiano, Jéssica Antonini; Nakamune, Ana Cláudia M S; Pessan, Juliano Pelim; Antoniali, Cristina

    2016-10-01

    This study aimed to evaluate the oxidative stress levels and the enzymatic and non-enzymatic antioxidant systems in saliva of toddlers with severe early childhood caries (S-ECC). Unstimulated saliva samples were collected at the morning from 0 to 3 year-old S-ECC (n=30) or caries-free (CF) children (n=30/group) for evaluation of oxidative stress (OS) and total antioxidant capacity (TAC), which were measured by the ferric reducing antioxidant power (FRAP) assay, as well as to assess the activity of enzymatic (superoxide dismutase, SOD) and non-enzymatic (uric acid, UA) antioxidant systems, respectively. Data were analyzed by Student's t-test (psaliva of S-ECC children (0.083mg/mL) than in the CF group (0.070mg/mL). Oxidative damage was significantly lower in saliva of S-ECC children (0.0019μmol/L/mg protein) than in CF children (0.0039μmol/L/mg protein), while salivary TAC (61.5μmol/L), SOD activity (36.6 UE/mL) and uric acid (7.05mg/mL) were significantly higher in saliva of S-ECC when compared to the CF group (49.1μmol/L, 26.8 UE/mL and 5.02mg/mL, respectively for TAC, SOD and UA). Oxidative stress levels were significantly lower in saliva of S-ECC children, what might be associated with the increased activity of salivary enzymatic (SOD) and non-enzymatic (uric acid) antioxidant systems. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Salivary peptidome profiling analysis for occurrence of new carious lesions in patients with severe early childhood caries.

    Science.gov (United States)

    Tian, Chang; Sun, Xiangyu; Liu, Xiaochen; Huang, Xin; Chen, Feng; Zheng, Shuguo

    2017-01-01

    This study aimed to identify differences of peptide profiles in stimulated whole saliva among children with and without occurrence of new carious lesions, and to provide a simple way for early diagnosis and prevention of the relapse of severe early childhood caries (s-ECC). Overall, 26 children aged 3-4 years were selected out from all the children in the kindergarten to be involved in the present study, among them 13 were diagnosed as s-ECC and underwent dental treatment, whilst the other 13 were matched by age and sex as control. Stimulated whole saliva samples were collected before treatment, and at 10 days and 4 months after treatment. During follow-up, 7 of the 13 children with s-ECC showed a relapse, and the new carious lesions were then treated. Salivary peptides were detected using the technique of magnetic beads combined with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). Fifteen peptides showed significant differences in the group without occurrence of new carious lesions (CH group). On comparing the CH group and the other group with occurrence of new carious lesions (CR group), no significant differences were observed before treatment, whereas certain peptides showed significant differences at both 10 days and 4 months after treatment. Two peptides (experimental m/z values: 3162.0 Da and 3290.4 Da) exhibited a consistent tendency in cross-sectional and longitudinal comparisons among these groups; these may be associated with recurrence of s-ECC. Based on our findings, it is concluded that different saliva peptide peaks can be detected in s-ECC using MALDI-TOF MS combined with magnetic beads. Moreover, 2 specific peptides with m/z values 3162.0 Da and 3290.4 Da could be promising salivary protein biomarkers for diagnosis of recurrence of s-ECC.

  11. First Euro-China Conference on Intelligent Data Analysis and Applications

    CERN Document Server

    Snasel, Vaclav; Corchado, Emilio; Abraham, Ajith; Wang, Shyue-Liang

    2014-01-01

    The First Euro-China Conference on Intelligent Data Analysis and Applications (ECC 2014), which was hosted by Shenzhen Graduate School of Harbin Institute of Technology and was held in Shenzhen City on June 13-15, 2014. ECC 2014 was technically co-sponsored by Shenzhen Municipal People’s Government, IEEE Signal Processing Society, Machine Intelligence Research Labs, VSB-Technical University of Ostrava (Czech Republic), National Kaohsiung University of Applied Sciences (Taiwan), and Secure E-commerce Transactions (Shenzhen) Engineering Laboratory of Shenzhen Institute of Standards and Technology.

  12. Time Course Change of IGF1/Akt/mTOR/p70s6k Pathway Activation in Rat Gastrocnemius Muscle During Repeated Bouts of Eccentric Exercise

    OpenAIRE

    Eisuke Ochi; Naokata Ishii; Koichi Nakazato

    2010-01-01

    The purpose of this study was to examine whether insulin-like growth factor (IGF-1) and Akt/mTOR/p70S6K pathway activity is altered by chronic eccentric exercise in rat medial gastrocnemius muscle. Male Wistar rats (n = 24) were randomly assigned to 1 of the 2 groups: eccentric exercise (ECC) group or sham-operated control (CON) group. Rats in the ECC group were trained every second day for 10 days (5 sessions in total) or 20 days (10 sessions in total). After either 5 or 10 exercise sessions...

  13. Impact of Flexibility Options on Grid Economic Carrying Capacity of Solar and Wind: Three Case Studies

    Energy Technology Data Exchange (ETDEWEB)

    Denholm, Paul [National Renewable Energy Lab. (NREL), Golden, CO (United States); Novacheck, Joshua [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jorgenson, Jennie [National Renewable Energy Lab. (NREL), Golden, CO (United States); O' Connell, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-12-01

    In this study, we attempt to quantify the benefits of various options of grid flexibility by measuring their impact on two measures: economic carrying capacity and system costs. Flexibility can increase ECC and reduce overall system costs. In some cases, options that provide a limited increase in ECC can provide significant operational savings, thus demonstrating the need to evaluate flexibility options using multiple metrics. The value of flexibility options varies regionally due to different generation mixes and types of renewables. The more rapid decline in PV value compared to wind makes PV more dependent on adding flexibility options, including transmission and energy storage.

  14. Prevalence and risk factors of caregiver reported Severe Early Childhood Caries in Manitoba First Nations children: results from the RHS Phase 2 (2008–2010

    Directory of Open Access Journals (Sweden)

    Robert J. Schroth

    2013-08-01

    Full Text Available Objectives. The high prevalence and severity of caries among Canadian First Nations children is a growing concern. Dental surgery in hospital is often necessary to treat the signs of decay but does not address the underlying factors contributing to its development. The purpose of this study was to determine the prevalence and risk factors of caregiver-reported Baby Bottle Tooth Decay (BBTD, or Severe Early Childhood Caries (S-ECC, among preschool children recruited in Phase 2 of the First Nations Regional Longitudinal Health Survey (RHS. Study Design. Cross-sectional study including interviews with caregivers. Methods. This study was limited to data from Manitoba First Nations participating in the RHS Phase 2 (2008–10. Data were restricted to caregiver interviews for their child <72 months of age. The main variable of interest was caregiver-reported BBTD, an antecedent term for S-ECC. Data analysis included descriptive statistics and bivariate analyses; p≤0.05 was significant. Results. Overall, caregivers of 431 preschool children responded. According to caregiver reports, 102/410 (24.9% children had S-ECC. Further, 65.0% responded that their child had already undergone treatment for caries. Children with S-ECC were significantly older than those without. S-ECC was also associated with paternal education levels and employment status, and maternal smoking during pregnancy. Breastfed children were less likely to have S-ECC, while consuming drink crystal beverages in bottles, and daily intake of soft drinks, juice, sweets and fast food were associated with increased risk. Those who reported that healthcare services were not available and were not culturally appropriate were significantly more likely to have children with S-ECC. Conclusions. Caregiver reports suggest that nearly 1 in every 4 children has been affected by S-ECC. Identified risk factors for Manitoba First Nations children included age, education and employment, dietary practices

  15. USING MODIFIED STERN SERIES FOR DIGITAL SIGNATURE AUTHENTICATION IN ELLIPTIC CURVE CRYPTOGRAPHY

    Directory of Open Access Journals (Sweden)

    Latha Parthiban

    2011-12-01

    Full Text Available This paper presents the generation of digital signature along with message recovery based on Elliptic Curve Cryptography (ECC and knapsack algorithm. In digital signature along with message recovery scheme, signature alone is sent and message is recovered from the signature (r, s. ECC provides greater security with less key size, when compared to integer factorization and discrete logarithm system. As the strength of knapsack algorithm depends on the selection of the series, the proposed algorithm uses modified Stern series which not only reduces the time complexity but also provides better security.

  16. Digital Multi-Signature Scheme Based on the Elliptic Curve Cryptosystem

    Institute of Scientific and Technical Information of China (English)

    Tzer-Shyong Chen; Kuo-Hsuan Huang; Yu-Fang Chung

    2004-01-01

    In the study,the digital multi-signature scheme,constructed by the integration of one-way hash function and identification scheme,are proposed based on the elliptic curve cryptosystem(ECC).To the efficiency in performance,the ECC has been generally regarded as positive; and the security caused by the Elliptic Curve Discrete Logarithm Problem(ECDLP)is highly also taken highly important.The main characteristic of the proposed scheme is that the length of the multi-signature is fixed rather than changeable and it will not increase with the number of group members.

  17. Ultra-Structural Changes of the Early Childhood Caries Starting Phases of Development

    Directory of Open Access Journals (Sweden)

    Kokoceva-Ivanovska Olga

    2014-03-01

    Full Text Available In the recent 20 years, besides dramatic reduction of caries in many countries where complex programme of prevention is carried out, prevalence of Early Childhood Caries (ECC has expressed continual growth trend. The aim of our research was to determine precisely ultra-structural changes in the enamel substance at the initial lesion of the ECC (white spot lesion, as initial change of great importance for its preventive aspect. Therefore, we directed our experiment to evaluate ultra-structural changes of the teeth enamel in primary teeth with circular caries in its opening stages of development: initial caries lesion and superficial form.

  18. Accurate and Simplified Prediction of AVF for Delay and Energy Efficient Cache Design

    Institute of Scientific and Technical Information of China (English)

    An-Guo Ma; Yu Cheng; Zuo-Cheng Xing

    2011-01-01

    With continuous technology scaling, on-chip structures are becoming more and more susceptible to soft errors. Architectural vulnerability factor (AVF) has been introduced to quantify the architectural vulnerability of on-chip structures to soft errors. Recent studies have found that designing soft error protection techniques with the awareness of AVF is greatly helpful to achieve a tradeoff between performance and reliability for several structures (i.e., issue queue, reorder buffer). Cache is one of the most susceptible components to soft errors and is commonly protected with error correcting codes (ECC). However, protecting caches closer to the processor (i.e., L1 data cache (L1D)) using ECC could result in high overhead. Protecting caches without accurate knowledge of the vulnerability characteristics may lead to over-protection. Therefore, designing AVF-aware ECC is attractive for designers to balance among performance, power and reliability for cache, especially at early design stage. In this paper, we improve the methodology of cache AVF computation and develop a new AVF estimation framework, soft error reliability analysis based on SimpleScalar. Then we characterize dynamic vulnerability behavior of L1D and detect the correlations between LID AVF and various performance metrics. We propose to employ Bayesian additive regression trees to accurately model the variation of L1D AVF and to quantitatively explain the important effects of several key performance metrics on L1D AVF. Then, we employ bump hunting technique to reduce the complexity of L1D AVF prediction and extract some simple selecting rules based on several key performance metrics, thus enabling a simplified and fast estimation of L1D AVF. Based on the simplified and fast estimation of L1D AVF, intervals of high L1D AVF can be identified online, enabling us to develop the AVF-aware ECC technique to reduce the overhead of ECC. Experimental results show that compared with traditional ECC technique

  19. Calculation of hyperfine structure constants of small molecules using Z-vector method in the relativistic coupled-cluster framework

    Indian Academy of Sciences (India)

    SUDIP SASMAL; KAUSHIK TALUKDAR; MALAYA K NAYAK; NAYANA VAVAL; SOURAV PAL

    2016-10-01

    The Z-vector method in the relativistic coupled-cluster framework is employed to calculate the parallel and perpendicular components of the magnetic hyperfine structure constant of a few small alkaline earth hydrides (BeH, MgH, and CaH) and fluorides (MgF and CaF). We have compared our Z-vector results with the values calculated by the extended coupled-cluster (ECC) method reported in Phys. Rev. A 91 022512 (2015). All these results are compared with the available experimental values. The Z-vector results are found to be in better agreement with the experimental values than those of the ECC values.

  20. Whole genome sequence of Enterobacter ludwigii type strain EN-119T, isolated from clinical specimens.

    Science.gov (United States)

    Li, Gengmi; Hu, Zonghai; Zeng, Ping; Zhu, Bing; Wu, Lijuan

    2015-04-01

    Enterobacter ludwigii strain EN-119(T) is the type strain of E. ludwigii, which belongs to the E. cloacae complex (Ecc). This strain was first reported and nominated in 2005 and later been found in many hospitals. In this paper, the whole genome sequencing of this strain was carried out. The total genome size of EN-119(T) is 4952,770 bp with 4578 coding sequences, 88 tRNAs and 10 rRNAs. The genome sequence of EN-119(T) is the first whole genome sequence of E. ludwigii, which will further our understanding of Ecc.

  1. 高韧性纤维增强水泥基复合材料与老混凝土的界面直剪试验研究%Experiment and Study on Direct Shear Behavior for Adhesion of Fiber Reinforced High Ductility Cementitious Composites on Existing Concrete

    Institute of Scientific and Technical Information of China (English)

    邓宗才; 薛会青

    2011-01-01

    Fiber reinforced high ductility cementitious composites(ECC) has high ductility and could effectively control micro-crack width. The experiment of direct shear behavior is researched for adhesion of ECC on existing concrete and provides records for retrofitting or strengthening concrete. Experimental results show that compressive and flexural strength of ECC are improved with increase of age; Interface shear strength of ECC bonding specimens is improved with increase of S/C, indicating the behavior of adhesion of ECC on existing concrete is improved with increase of S/C; The behavior of adhesion of ECC on existing concrete is much better than on self-compacting concrete and plain concrete. ECC is perfect material for retrofitting deck and pavement, strengthening reservoir and dam.%高韧性纤维增强水泥基复合材料(ECC)具备很好的延展性和微裂缝宽度控制能力,通过ECC与老混凝土之间的界面直剪试验,研究高韧性复合材料与普通混凝土之间的界面黏结性能,为混凝土工程的维修或加固提供试验数据.试验结果表明:随着龄期的增加,ECC抗压强度与抗折强度逐渐提高;随着砂灰比的增加,ECC黏结试件的界面抗剪强度逐渐提高,说明增加砂灰比可以提高ECC与老混凝土间的界面黏结性能;ECC与老混凝土间的界面黏结性能远优于自密实混凝土和普通混凝土,高韧性水泥基复合材料是修补桥面、路面和加固水库、大坝等混凝土工程的理想材料.

  2. Integral equation for the interfacial tension of liquid metal in contact with ionic melt

    CERN Document Server

    Kobelev, O A; Kobelev, Oleg A.; Kobelev, Alexandr V.

    2004-01-01

    The closed integral equations for the interfacial tension as a function of external polarization at the liquid metal - ionic melt interface are derived. The version of Popel'-Pavlov isotherm is applied to the analysis of electrocapillary curves (ecc), i.e. the dependences of interfacial tension on electrode potential. The interaction between adsorbed particles is taken into account within 'two exchange parameters' approximation. The type of the distribution of electric potential in the double electric layer (del) is assumed to be like 'in series connected capacitors'. The methods of solution are proposed for the analysis of the experimental ecc's.

  3. Public Health Aspects of Paediatric Dental Treatment under General Anaesthetic

    Directory of Open Access Journals (Sweden)

    William Murray Thomson

    2016-06-01

    Full Text Available Early childhood caries (ECC has negative psychosocial effects on children, with chronic pain, changed eating habits, disrupted sleep and altered growth very common, and it disrupts the day-to-day lives of their families. The treatment of young children with ECC places a considerable burden on health systems, with a considerable amount having to be provided under general anaesthesia (GA, which is resource-intensive. Justifying its use requires evidence of the efficacy of treatment in improving the lives of affected children and their families. This paper discusses the available evidence and then makes some suggestions for a research agenda.

  4. ACTUAL-WASTE TESTS OF ENHANCED CHEMICAL CLEANING FOR RETRIEVAL OF SRS HLW SLUDGE TANK HEELS AND DECOMPOSITION OF OXALIC ACID

    Energy Technology Data Exchange (ETDEWEB)

    Martino, C.; King, W.; Ketusky, E.

    2012-01-12

    Savannah River National Laboratory conducted a series of tests on the Enhanced Chemical Cleaning (ECC) process using actual Savannah River Site waste material from Tanks 5F and 12H. Testing involved sludge dissolution with 2 wt% oxalic acid, the decomposition of the oxalates by ozonolysis (with and without the aid of ultraviolet light), the evaporation of water from the product, and tracking the concentrations of key components throughout the process. During ECC actual waste testing, the process was successful in decomposing oxalate to below the target levels without causing substantial physical or chemical changes in the product sludge.

  5. The relationship between cytokine level and nitric oxide content in aqueous humor after intraocular lens implantation

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    AIM: To investigate the relationship between cytokine level and nitric oxide (NO) content in aqueous humor after intraocular lens implantation. METHODS: All New Zealand rabbits were divided randomly into three groups: (1) control group, (2) extracapsular cataract extraction group (ECCE), (3) extracapsular cataract extraction and posterior chamber intraocular lens implantation group (ECCE+IOL). The inflammation of all experimental rabbit eyes, including cornea edema and anterior chamber exudation were observed via zoom-photo slitlamp microscope 1,3,7,14,30 d postoperation. Meanwhile, aqueous humor was drawn for white blood cell (WBC) counting and classifying, and for NO-2/NO-3 and cytokine assay, including interleukin-2(IL-2), tumour necrosis factor-α(TNF-α). Statistics were taken by SPSS softwear. RESULTS: (1) Total WBC in aqueous humor were higher and anterior chamber exudation were more severe in ECCE+IOL group than that in ECCE group and control group. (2) The level of IL-2 and TNF-α and the content of NO-2/NO-3 in aqueous humor of ECCE+IOL group were higher than that in ECCE group and control group 1-14 d postoperation respectively, and it increased to peak value at 3-7 d postoperation and decreased gradually after two weeks postoperation. (3) The change regularity of IL-2, TNF-α and NO-2/NO-3 in each group were basically similar, i.e. when the level of cytokine (IL-2 and TNF-α) was normal, the content of NO-2/NO-3 was normal too, when the level of cytokine (IL-2 and TNF-α) increased, the content of NO-2/NO-3 increased too. CONCLUSION: The intraocular inflammation after ECCE+IOL was more severe than that after simple ECCE. NO, IL-2 and TNF-α play an important role in intraocular inflammation after intraocular lens implantation. The changes of IL-2 and TNF-α level was closely related with NO content in aqueous humor.

  6. A NEW ANONYMITY CONTROLLED E-CASH SCHEME

    Institute of Scientific and Technical Information of China (English)

    Zhang Fangguo; Wang Changjie; Wang Yumin

    2002-01-01

    E-cash is a type of very important electronic payment systems. The complete anonymity of E-cash can be used for criminal activities, so E-cash should be anonymity controlled.Moreover, Elliptic Curve Cryptography(ECC) has been regard as the mainstream of current public cryptography . In this paper, a new anonymity controlled E-cash scheme based on ECC for the first time and using a new technology-one-time key pairs digital signature is designed, and its security and efficiency are analyzed. In our scheme, the coin tracing and owner tracing can be implemented.

  7. Application of combined ultrafiltration and vaccum-assisted venous drainage in extracorporeal circulation for open heart surgery in infants

    Directory of Open Access Journals (Sweden)

    Tao ZHANG

    2014-03-01

    Full Text Available Objective To summarize the managerial experiences in the application of combined ultrafiltration and vaccum-assisted venous drainage (VAVD in extracorporeal circulation (ECC for congenital heart diseases operation in infants. Methods The clinical data of 72 infants [42 males and 30 females, aged 14d to 24 months (13.1±6.2 months, body weight 3.4- 10(8.18±1.88kg], who underwent operation to correct congenital heart diseases from Jan 2011 to Dec 2012, were retrospectively analyzed. Forty-four of the 72 infants were suffering from simple congenital heart diseases (atrial or interventricular septal defect, and 28 with complicated congenital heart diseases (tetralogy of Fallot, partial/complete atrioventricular canal, double outlet of right ventricle, etc.. Membrane oxygenator (Terumo Baby-RX or Maquet VKMO 10000 was used in ECC, and the volume of priming solution (Ringer lactate solution and human serum albumin was 250-450ml. During ECC, the perfusion flow rate was 90-150ml/ (kg.min, mean arterial pressure was maintained at 35-50mmHg, hematocrit (Hct at 0.20-0.30, and rectal temperature at 25- 32℃. Histidine-Tryptophan-Ketoglutarate (HTK solution was used for myocardial preservation during the operation. VAVD was routinely used in ECC with negative pressure of –10 to –30mmHg. The combined ultrafiltration technique was also routinely used, i.e. conventional ultrafiltration was applied in ECC and modified ultrafiltration was applied after ECC. Results The ECC time was 30-174 (82.6±31.2min and aortic clamping time was 6-125 (51.7±30.1min. The peripheral circulation and arterial blood gas values were normal during ECC in 72 infants, and the cardiac spontaneous resuscitation rate was 94.4%(68/72 cases. The volume of conventional ultrafiltration during ECC was 60-380ml and the volume of modified ultrafiltration after ECC was 50-230ml. After the end of modified ultrafiltration, Hct was 0.32±0.11. The volume of intraoperative red blood cell

  8. Parâmetros reprodutivo e metabólico de vacas da raça Guzerá suplementadas no pré e pós-parto Reproductive and metabolic parameters of Guzerá cows supplemented in pre and postpartum

    Directory of Open Access Journals (Sweden)

    Marcelo Marcondes de Godoy

    2004-02-01

    Full Text Available Foram utilizadas 30 vacas da raça Guzerá (10 por tratamento, suplementadas no pré-parto (PRE, pós-parto (POS e sem suplementação (SS com os objetivos de avaliar no pós-parto as variações do peso corporal (PC, do escore de condição corporal (ECC (1 = muito magra a 9 = muito gorda e dos níveis plasmáticos de colesterol total (NPCT, o índice de prenhez (IP até 112 dias pós-parto e a viabilidade econômica dos tratamentos PRE e POS, que constou de 1 kg/dia/animal de concentrado (16% PB; 3000 kcal ED/kg. O PC e o ECC foram obtidos a cada 28 dias, e colheitas de sangue semanalmente para análise dos NPCT até 112 dias pós-parto. O PC e o ECC tiveram interação dias pós-parto x tratamento. O tratamento PRE aumentou o PC e o ECC das vacas ao parto: 477,80 kg e 6,20 respectivamente, em comparação com os tratamentos POS e SS de 453,37 kg e 5,5; 447,57 kg e 5,28, respectivamente. O PC e o ECC do tratamento PRE foi superior de 28 a 84 dias comparado ao SS, enquanto o tratamento POS foi superior apenas de 84 a 112 dias pós-parto. O tratamento POS não diferiu do PRE no PC de 56 a 112 dias pós-parto e no ECC de 28 a 112 dias pós-parto. O tratamento POS proporcionou aumento do PC e ECC das vacas, já os tratamentos PRE e SS perderam PC e ECC até 112 dias pós-parto. O PC e ECC dos tratamentos PRE, POS e SS aos 112 dias pós-parto foram de 457,79 kg e 5,38; 461,87 kg e 5,66; 436,57 kg e 4,78, respectivamente. Os NPCT tiveram efeito dos dias pós-parto, mas não de tratamento, aumentando com os dias pós-parto. Os IP não foram influenciados pelos tratamentos PRE, POS e SS com 50,00; 62,20 e 57,14%, respectivamente. Economicamente a suplementação não foi viável.Thirty Guzera cows (10 by treatment, supplemented in the prepartum (PRE and postpartum (POS and without supplementation (SS were used to evaluate, in the postpartum, the variation of body weight (BW, body condition score (BCS (1 = very thin to 9 = very fat and levels of serum

  9. Analysis in primary clinic outcomes of minimal extracorpeal circulation in the coronary artery bypass grafting%微创体外循环在冠状动脉旁路移植术中初步临床应用分析

    Institute of Scientific and Technical Information of China (English)

    刘燕; 陶凉; 崔虎军; 陈绪发

    2008-01-01

    Objective To analysis comparatively the primary clinic outcomes between minimal extracorporeal circulation (MECC) and conventional extracorporeal circulation (cECC). Methods Forty cases accepted coronary artery bypass grafting from August to October at 2006 were divided into MECC group and cECC group at random, 20 cases for each group. Record and analysis of the general information, clinic data perioperatively, and complications postoperatively for each group were performed. Results There were no deference between groups in gender, anamnesis and preoperative cardiac function, while age (P<0.05), standard EuroSCORE and logistic EuroSCORE were much more higher in MECC group than in cECC group (P<0.01). Similarly, there were no deference in operative time, bypass time, ischemic time and graft number between two groups. Contrasted with cECC group, the values of cTNI were lower in MECC group at 2 h, 6 h and 12 h post-ECC (P<0.01), oxygen index were higher post-operatively and there was a statistic deference at 12 h post-ECC (P<0.05). The valves of ALT and TBIL in cECC group were higher abnormally at early post-ECC, and significant higher than in MECC group at 2 h, 6 h post-ECC of ALT (P<0.05), and at termination, 2 h post-ECC of TBIL (P<0.05). The values of actived partial thromboplastin time were almost at physiological status in MECC group, but were significantly prolonged in cECC group at early post-ECC, and were statisticly longer than in MECC group at 2 h, 6 h, 12 h post-ECC (P<0.05). The concentration of free hemoglobin in cECC group were higher than in MECC group peri-operative, and there was a statistic deference at 2 h post-ECC (P<0.05). There were no deference between the two group in Cr, PLT and WBC. Conclusions Compared with cECC, MECC carries more biocompatibility, more safe and credible. MECC system can alleviate the organ injury postoperatively and decrease the incidence of complications, especially in high-risk patients.%目的 比较微创体外循

  10. Incompatibility between Zircaloy-2 and Inconel X-750 during Temperature Transients

    DEFF Research Database (Denmark)

    Warren, M. R.; Rørbo, Kaj; Adolph, Eivind

    1975-01-01

    The incompatibility of Zircaloy-2 and Inconel X-750 has been investigated between 1000°C and 1200°C (1200°C being the currently allowable maximum temperature in the acceptance criteria for ECCS for water reactors). It has been found for the temperatures of 1000°C and 1200°C that oxide thicknesses...

  11. Evaluation of Early Childhood Coaching Implementation in Nebraska. Technical Report Vol. 1: Key Findings from Participant Follow Up Survey. CYFS Working Paper 2014-1

    Science.gov (United States)

    Jayaraman, Gayatri; Knoche, Lisa; Marvin, Christine; Bainter, Sue

    2014-01-01

    The Nebraska Early Childhood Coach (ECC) training was a 3 day (8 hours) professional development event sponsored by the Nebraska Department of Education, Office of Child Development in 2009-2010. Sixty-five early childhood teachers and related service providers participated for the purpose of learning the basic principles and behaviors associated…

  12. Evaluation of Early Childhood Coaching Implementation in Nebraska. Technical Report Vol. 2: Key Findings from Participant Observational and Self-Reported Data. CYFS Working Paper 2014-2

    Science.gov (United States)

    Jayaraman, Gayatri; Knoche, Lisa; Marvin, Christine; Bainter, Sue

    2014-01-01

    The Nebraska Early Childhood Coach (ECC) training was a 3 day (8 hours) professional development event sponsored by the Nebraska Department of Education, Office of Child Development in 2009-2010. Sixty-five early childhood teachers and related service providers participated for the purpose of learning the basic principles and behaviors associated…

  13. Minimal intervention dentistry for early childhood caries and child dental anxiety: a randomized controlled trial.

    Science.gov (United States)

    Arrow, P; Klobas, E

    2017-06-01

    To compare changes in child dental anxiety after treatment for early childhood caries (ECC) using two treatment approaches. Children with ECC were randomized to test (atraumatic restorative treatment (ART)-based approach) or control (standard care approach) groups. Children aged 3 years or older completed a dental anxiety scale at baseline and follow up. Changes in child dental anxiety from baseline to follow up were tested using the chi-squared statistic, Wilcoxon rank sum test, McNemar's test and multinomial logistic regression. Two hundred and fifty-four children were randomized (N = 127 test, N = 127 control). At baseline, 193 children completed the dental anxiety scale, 211 at follow up and 170 completed the scale on both occasions. Children who were anxious at baseline (11%) were no longer anxious at follow up, and 11% non-anxious children became anxious. Multinomial logistic regression found each increment in the number of visits increased the odds of worsening dental anxiety (odds ratio (OR), 2.2; P anxiety (OR, 0.50; P = 0.05). The ART-based approach to managing ECC resulted in similar levels of dental anxiety to the standard treatment approach and provides a valuable alternative approach to the management of ECC in a primary dental care setting. © 2016 Australian Dental Association.

  14. The Expanded Core Curriculum at the Indiana School for the Blind and Visually Impaired: A Case Study

    Science.gov (United States)

    Ringwalt, Gail Mulholland

    2013-01-01

    This case study investigated how the Expanded Core Curriculum (ECC) was taught to high school students who are blind or visually impaired at the Indiana School for the Blind and Visually Impaired (ISBVI). The study focused on three students pursing different academic tracks with varying degrees of vision. The students were observed throughout…

  15. 75 FR 36698 - Draft Regulatory Guide: Issuance, Availability

    Science.gov (United States)

    2010-06-28

    ... system (ECCS). The proposed rule, 10 CFR 50.46a, ``Risk-Informed Changes to Loss-of-Coolant Accident... largest pipe in the reactor coolant system. Selection of the transition size was based upon pipe break... Cooling Systems for Light-Water Nuclear Power Reactors,'' as set forth in Appendix A, ``General...

  16. A Bit-Serial Multiplier Architecture for Finite Fields Over Galois Fields

    Directory of Open Access Journals (Sweden)

    Hero Modares

    2010-01-01

    Full Text Available Problem statement: A fundamental building block for digital communication is the Public-key cryptography systems. Public-Key Cryptography (PKC systems can be used to provide secure communications over insecure channels without exchanging a secret key. Implementing Public-Key cryptography systems is a challenge for most application platforms when several factors have to be considered in selecting the implementation platform. Approach: The most popular public-key cryptography systems nowadays are RSA and Elliptic Curve Cryptography (ECC. ECC was considered much more suitable than other public-key algorithms. It used lower power consumption, has higher performance and can be implemented on small areas that can be achieved by using ECC. There is no sub exponential-time algorithm in solving the Elliptic curve discrete logarithm problem. Therefore, it offers smaller key size with equivalent security level compared with the other public key cryptosystems. Finite fields (or Galois fields is considered as an important mathematical theory. Results: Thus, it plays an important role in cryptography. As a result of their carry free arithmetic property, they are suitable to be used in hardware implementation in ECC. In cryptography the most common finite field used is binary field GF (2m. Conclusion: Our design performs all basic binary polynomial operations in Galois Field (GF using a microcode structure. It uses a bit-serial and pipeline structure for implementing GF operations. Due to its bit-serial architecture, it has a low gate count and a reduced number of I/O pins.

  17. InterProScan Result: FS869288 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS869288 FS869288_5_ORF2 1D3ECC3A57ADFC41 PFAM PF00361 Oxidored_q1 4.6e-11 T IPR001...750 NADH:ubiquinone/plastoquinone oxidoreductase Molecular Function: NADH dehydrogenase (ubiquinone) activit

  18. Contextualized Mathematics Instruction: Moving beyond Recent Proposals.

    Science.gov (United States)

    Heckman, Paul E.; Weissglass, Julian

    1994-01-01

    Discusses situated cognition and anchored instruction and makes recommendations for effecting change in mathematics curricula in the early school years based on the experience of the Educational and Community Change (ECC) Project, which is involved with reinventing education in a low-income, multilanguage area. (Contains 26 references.) (MKR)

  19. Pop / Mart Kuldkepp

    Index Scriptorium Estoniae

    Kuldkepp, Mart

    2007-01-01

    Heliplaatidest: Korn "Untitled", Editors "An End Has A Start", Dinosaur Jr "Beyond", Paul McCartney "Ecce Cor Meum - Behold My Heart" ja "Memory Almost Full, James Pennington presents Dark Energy "Collided Energy", Yeah Yeah Yeahs "Is Is EP", Talib Kweli"Eardrum"

  20. Crystalline Ultrastructures, Inflammatory Elements, and Neoangiogenesis Are Present in Inconspicuous Aortic Valve Tissue

    Directory of Open Access Journals (Sweden)

    P. Dorfmüller

    2010-01-01

    Full Text Available Morbidity from calcific aortic valve disease (CAVD is increasing. Recent studies suggest early reversible changes involving inflammation and neoangiogenesis. We hypothesized that microcalcifications, chemokines, and growth factors are present in unaffected regions of calcific aortic valves. We studied aortic valves from 4 patients with CAVD and from 1 control, using immunohistochemistry, scanning electron microscopy, and infrared spectrography. We revealed clusters of capillary neovessels in calcified (ECC, to a lesser extent in noncalcified (ECN areas. Endothelial cells proved constant expression of SDF-1 in ECC, ECN, and endothelial cells from valvular surface (ECS. Its receptor CXCR4 was expressed in ECC. IL-6 expression correlated with CXCR4 staining and presence of lymphocytes. VEGF was expressed by ECS, its receptor by ECC and ECN. Crystalline ultrastructures were found on the surface of histologically noncalcified areas (HNCAs, spectrography revealed calcium hydroxylapatite. Our results demonstrate that crystalline ultrastructures are present in HNCAs, undergoing neoangiogenesis in an inflammatory context. These alterations could be an early witness of disease and an opening to therapy.

  1. Effects of submaximal eccentric exercise on muscle activity at different elbow joint angles.

    Science.gov (United States)

    Kisiel-Sajewicz, Katarzyna; Jaskólska, Anna; Janecki, Damian; Andrzejewska, Renata; Marusiak, Jarosław; Jaskólski, Artur

    2014-01-01

    Our study aimed to determine whether electrical and mechanical factors contributing to acute or long-term maximal torque reduction and muscle soreness due to submaximal eccentric exercise (ECC) are elbow-joint-angle specific and to what extent the joint angle affects the contribution of antagonist coactivation to this torque reduction. Maximal isometric torque (MIT), muscle soreness assessment, agonist electromechanical activities, and antagonist coactivation during the maximal voluntary contraction (MVC) were measured at elbow joint angles of 60°, 90°, and 150° before ECC, immediately after exercise, and 24, 48, 72, and 120 hr after exercise. ECC causes an immediate decrease in MIT as well as increased antagonist coactivation at three angles. Antagonist coactivation returned to its baseline level at 24 hr regardless of joint angle. The most rapid torque recovery and the highest force level at which pain occurred were found after ECC at a joint angle of 60°. During the recovery period, no mechanomyographical changes were observed when measuring surface mechanomyography changes at three angles, while the electrical activity differed between angles.

  2. Effect of a Short Time Concentric Versus Eccentric Training Program on Electromyography Activity and Peak Torque of Quadriceps

    DEFF Research Database (Denmark)

    Carvalho, Alberto; Caserotti, Paolo; Carvalho, C.

    2014-01-01

    The purpose of this study was to examine the effect of an 8-week concentric (CON) versus eccentric (ECC) isokinetic training program on the electromyography (EMG) signal amplitude of vastus medialis (VM), vastus lateralis (VL) and rectus femoris (RF). Also, the isometric (ISO) and dynamic maximum...

  3. Effects of different accentuated eccentric loads on acute neuromuscular, growth hormone, and blood lactate responses during a hypertrophic protocol.

    Science.gov (United States)

    Ojasto, Timo; Häkkinen, Keijo

    2009-05-01

    This study monitored acute neuromuscular responses and growth hormone (GH) and blood lactate (La) concentrations in the eccentric-concentric (ECC-CON) hypertrophic protocol by using various dynamic accentuated external resistance (DAER) loads in the bench press exercise. Male subjects (age = 32 +/- 4 years; n = 11) performed 4 sets of 10 repetitions with 2 minutes of recovery between the sets. The loads were 70, 80, 90, and 100% of 1 repetition maximum (RM) for the ECC phase, whereas 70% RM was constantly used for the CON phase. Electromyographic activity (EMG), ECC, CON, and isometric (ISOM) forces, serum GH and blood La, were measured at pre- and postloading. Significant reductions occurred in ISOM and CON pre- to postforces in all loading conditions (p 3.5 +/- 1.5 microgxL in the control condition, but the difference did not reach statistical significance. ECC EMG of the agonists increased with the increase in load but significantly only in the deltoid anterior (p exercise protocols in training for muscle hypertrophy and suggest the importance of individualized load selection for DAER exercises.

  4. Synergies and trade-offs between ecosystem service supply, biodiversity, and habitat conservation status in Europe

    NARCIS (Netherlands)

    Maes, J.; Paracchini, M.L.; Zulian, G.; Dunbar, M.B.; Alkemade, J.R.M.

    2012-01-01

    In the European Union (EU) efforts to conserve biodiversity have been consistently directed towards the protection of habitats and species through the designation of protected areas under the Habitats Directive (92/43/ECC). These biodiversity conservation efforts also have the potential to maintain

  5. In-Course Instructor-Guided Service Learning in a Community College General Psychology Class

    Science.gov (United States)

    Goomas, David T.; Weston, Melissa B.

    2012-01-01

    Students enrolled in two general psychology classes at El Centro College (ECC) of the Dallas County Community College District (DCCCD) were offered the opportunity to earn extra credit by performing up to 20 hours of service learning. Benefits of service learning were observed in student development, including exploration of career possibilities,…

  6. Interactive Naval Gunfire Support Training

    Science.gov (United States)

    1992-03-01

    OVERCOMING INERTIA: WINNING THE TRAINING WAR "Nothing on earth consumes a man more quickly than the passion of resentment." This was written by Friedrich ... Nietzche in Ecce Homo over a hundred years ago, but very aptly describes the attitude about training. Many times deficiencies in training are perceived

  7. Modeling of the Radiation Doses during Dismantling of RBMK-1500 Reactor Pressurized Tanks from Emergency Core Cooling System

    Directory of Open Access Journals (Sweden)

    A. Simonis

    2013-01-01

    Full Text Available Decommissioning of the Ignalina Nuclear Power Plant involves multiple problems. One of them is personnel radiation safety during the performance of dismantling activities. In this paper, modeling results of radiation doses during the dismantling of the pressurized tank from the emergency core cooling system (ECCS PT of RBMK-1500 reactor are presented. The radiological surveys indicate that the inner surface of the ECCS PT is contaminated with radioactive products of corrosion and sediments due to the radioactive water. The effective doses to the workers have been modeled for different strategies of ECCS PT dismantling. In order to select the optimal personnel radiation safety, the modeling has been performed by the means of computer code “VISIPLAN 3D ALARA Planning tool” developed by SCK CEN (Belgium. The impacts of dismantling tools, shielding types, and extract ventilation flow rate on effective doses during the dismantling of ECCS PT have been analyzed. The total effective personnel doses have been obtained by summarizing the effective personnel doses from various sources of exposure, that is, direct radiation from radioactive equipment, internal radiation due to inhalation of radioactive aerosols, and direct radiation from radioactive aerosols arising during hot cutting in premises. The uncertainty of the collective doses is also presented in this paper.

  8. The Serratia LuxR family regulator CarR 39006 activates transcription independently of cognate quorum sensing signals.

    Science.gov (United States)

    Poulter, Simon; Carlton, Timothy M; Spring, David R; Salmond, George P C

    2011-05-01

    In Gram-negative bacteria, quorum sensing control of gene expression is mediated by transcription factors of the LuxR family, whose DNA-binding affinity is modulated by diffusible N-acyl homoserine lactone (AHL) signalling molecules. In Serratia sp. ATCC 39006 and the plant pathogen Erwinia carotovora ssp. carotovora (Ecc), the biosynthesis of the β-lactam antibiotic 1-carbapen-2-em-3-carboxylic acid (Car) is under quorum sensing control. This study has revealed that, uniquely, the LuxR family transcriptional activator CarR(39006) from Serratia 39006 has no detectable affinity for cognate AHL molecules. Furthermore, CarR(39006) was shown to be naturally competent to bind to its target promoter with high affinity, activate transcription and resist cellular proteolysis, and was unaffected by AHL signals. Experiments with chimeric proteins suggest that the C-terminal DNA-binding domain of CarR(39006) may be responsible for conferring AHL independence. In contrast, we show that the homologous CarR(Ecc) protein binds to its 3O-C6-HSL ligand with high affinity, and that the highly conserved Trp-44 residue is critical for this interaction. Unlike TraR from Agrobacterium tumefaciens, CarR(Ecc) is not directly protected from cellular proteolysis by AHL binding, but via AHL-induced DNA binding. At physiological protein concentrations, AHL binding induces CarR(Ecc) to bind to its target promoter with higher affinity and activate transcription. © 2011 Blackwell Publishing Ltd.

  9. Rice husk ash as corrective of soil acidity

    Directory of Open Access Journals (Sweden)

    Gláucia Oliveira Islabão

    2014-06-01

    Full Text Available Rice husk ash (RHA is a by-product from the burning of rice husk that can have favorable effects on the soil in terms of acidity correction. The objectives of this study were to determine the effective calcium carbonate equivalent (ECC of RHA under field conditions, and establish technical criteria as a basis for estimating the overall ECC of RHA. The 12 treatments of the experiment consisted of 10 RHA dosages (0, 10, 20, 30, 40, 60, 80, 100, 120, and 140 Mg ha-1 and two references, one of which was an absolute control (AC and the other a plot limed and fertilized according to official recommendations (recommended fertilization - RF. The soil was sampled twice (15 and 210 days after incorporating RHA, in the layers 0.00-0.10 and 0.10-0.20 m, to determine the pH(H2O and base saturation (V%. The ECC and neutralizing value (NV of RHA were also determined. The results showed that RHA neutralizes soil acidity, in a faster reaction than conventional limestone, despite a low ECC (around 3 %.

  10. Accounting Control Technology Using SAP: A Case-Based Approach

    Science.gov (United States)

    Ragan, Joseph; Puccio, Christopher; Talisesky, Brandon

    2014-01-01

    The Sarbanes-Oxley Act (SOX) revolutionized the accounting and audit industry. The use of preventative and process controls to evaluate the continuous audit process done via an SAP ERP ECC 6.0 system is key to compliance with SOX and managing costs. This paper can be used in a variety of ways to discuss issues associated with auditing and testing…

  11. Early Childhood Dental Caries: A Rising Dental Public Health Crisis

    Science.gov (United States)

    Gomez, Grace Felix

    2013-01-01

    The aim of this article is to examine the literature and review the risk factors and disparities contributing to early childhood caries (ECC), which is a major health problem among preschoolers in the United States of America. A search was conducted using MEDLINE, PubMed, Google Scholar, and the Cochrane Library databases and the key terms…

  12. One-step Multiplex RT-PCR Method for Simultaneous Detection of Seed Transmissible Bacteria and Viruses in Pepper and Tomato Seeds

    Directory of Open Access Journals (Sweden)

    Kyusik Jeong

    2011-04-01

    Full Text Available The aim of this study was to develop specific and sensitive PCR-based procedures for simultaneous detection of economically important plant seed infection pathogenic bacteria and virus, Xanthomonns campestris pv. vesicatoria (Xcv, Clavibacter michiganensis subsp. michiganensis (Cmm, Erwinia carotovora subsp. carotovora (Ecc, Pepper mild mottle virus (PMMoV and Tobacco mild green mosaic virus (TMGMV in pepper and tomato seeds. Most of pepper and tomato bacterial and virus diseases are responsible for germination and growth obstruction. PCR with arbitral primers: selection of specific primers, performance of PCR with specific primers and determination of the threshold level for pathogens detection. To detect simultaneously the Xcv, Cmm, Ecc, PMMoV and TMGMV in pepper and tomato seeds, five pairs (Cmm-F/R, Ecc-F/R, Xcv-F/R, PMMoV-F/R, TMGMV-F/R of specific primer were synthesized by primer-blast program. The multiplex PCR for the five pathogens in pepper and tomato seeds could detect specially without interference among primers and/or cDNA of plant seeds and other plant pathogens. The PCR result for pathogen detection using 20 commercial pepper and 10 tomato seed samples, Ecc was detected from 4 pepper and 2 tomato seed samples, PMMoV was detected from 1 pepper seed sample, and PMMoV and TMGMV were simultaneously detected from 1 pepper seed sample.

  13. Effects of low-intensity concentric and eccentric exercise combined with blood flow restriction on indices of exercise-induced muscle damage

    Science.gov (United States)

    Yasuda, Tomohiro; Loenneke, Jeremy P.; Abe, Takashi

    2013-01-01

    Low-intensity blood-flow restriction (BFR) resistance training significantly increases strength and muscle size, but some studies report it produces exercise-induced muscle damage (EIMD) in the lower body after exercise to failure. Purpose: To investigate the effects of a pre-set number of repetitions of upper body concentric and eccentric exercise when combined with BFR on changes in EIMD. Methods: Ten young men had arms randomly assigned to either concentric BFR (CON-BFR) or eccentric BFR (ECC-BFR) dumbbell curl exercise (30% one-repetition maximum (1-RM), 1 set of 30 repetitions followed by 3 sets of 15 repetitions). Maximal isometric voluntary contraction force (MVC), muscle thickness (MTH), circumference, range of motion (ROM), ratings of perceived exertion (RPE), and muscle soreness were measured before, immediately after, and daily for 4 days post-exercise. Results: MVC decreased by 36% for CON-BFR and 12% for ECC-BFR immediately after exercise but was not changed 1–4 days post-exercise (p > 0.05). Only CON-BFR had significant changes in MTH and circumference immediately after exercise (p exercise. Conclusions: Low-intensity ECC-BFR produces significant muscle soreness at 24 h but neither ECC-BFR nor CON-BFR exercise produces significant changes in multiple indices of EIMD. PMID:24265891

  14. Corticosteroid injections, eccentric decline squat training and heavy slow resistance training in patellar tendinopathy

    DEFF Research Database (Denmark)

    Kongsgaard, M; Kovanen, V; Aagaard, P

    2009-01-01

    A randomized-controlled single-blind trial was conducted to investigate the clinical, structural and functional effects of peritendinous corticosteroid injections (CORT), eccentric decline squat training (ECC) and heavy slow resistance training (HSR) in patellar tendinopathy. Thirty-nine male...

  15. Specific training improves skeletal muscle mitochondrial calcium homeostasis after eccentric exercise.

    Science.gov (United States)

    Rattray, Ben; Thompson, Martin; Ruell, Patricia; Caillaud, Corinne

    2013-02-01

    There is limited understanding of the mitochondrial adaptation following repeated eccentric exercise bouts, a model resulting in muscle adaptation known as the repeat bout effect. It was hypothesized that downhill training would reduce mitochondrial calcium content (MCC) post an acute eccentric bout with concurrent improvements in mitochondrial respiratory function. Thirty-four Sprague-Dawley rats were divided into four groups: control (N), control with acute eccentric exercise (N (ecc)), trained control (X) and trained with acute eccentric exercise (X (ecc)). Training for X and X (ecc) consisted of 30 min per day for five consecutive days of downhill treadmill running. The acute eccentric exercise bout was a -14° treadmill exercise for 90 min performed 2 weeks after the training period. Animals were killed 48 h post-exercise. Isolated mitochondria from the red quadriceps allowed for the measure of mitochondrial respiratory indices and MCC. Calpain activity and heat shock protein 72 expression (HSP72) were also measured. MCC dramatically increased following the acute bout of eccentric exercise in N (ecc) (p eccentric exercise. The results suggest that downhill exercise training improves mitochondrial calcium homeostasis following an acute bout of prolonged eccentric exercise and may stabilize mitochondrial respiratory function. These improvements coincide with a reduction in calpain activity and heat shock protein upregulation.

  16. Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy

    DEFF Research Database (Denmark)

    Beyer, Rikke; Kongsgaard, Mads; Hougs Kjær, Birgitte

    2015-01-01

    BACKGROUND: Previous studies have shown that eccentric training has a positive effect on Achilles tendinopathy, but few randomized controlled trials have compared it with other loading-based treatment regimens. PURPOSE: To evaluate the effectiveness of eccentric training (ECC) and heavy slow...

  17. Tudengimaal, köited, auväärne graafika / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2003-01-01

    TÜ maalikunsti üliõpilaste näitus "Tartu kevad" Kastellaanimaja galeriis; Pille Kivihalli, Tiina Piisangu ja Maarja Unduski näitus "Ecce libris" Tallinna Kunstihoone galeriis; Eesti ja Taani graafikanäitus "Hjorring-Tallinn 2003" Hobusepea galeriis

  18. Sequencing of Escherichia coli that cause persistent and transient Mastitis

    Science.gov (United States)

    The genomes of two strains of Escherichia coli that cause bovine mastitis were sequenced. These strains are known to be associated with persistent and transient mastitis: strain ECA-B causes a transient infection, and ECC-M leads to a persistent infection....

  19. An Energy-Efficient Cluster-Head Selection Protocol for Energy-Constrained Wireless Sensor Networks

    Science.gov (United States)

    Hao, Peng; Qiu, Wanzhi; Evans, Rob

    In clustered wireless sensor networks, cluster-heads (CHs) are the key. And the CH selection methods can affect the efficiency of the cluster and even influence the lifetime of an energy-constrained network. In this paper, we propose the Energy-consumption-cycle based Cluster-heads Selection (ECHS) protocol. ECHS selects CHs via two phases. In the first phase, CH candidates are chosen based on an adaptable energy threshold and the status of neighbor nodes. In the second phase, each candidate computes its own Energy Consumption Cycles (ECC), which is relevant to the CH candidate's residual energy and the energy consumption when communicating with its neighbor nodes. The ECC actually evaluates the lifetime of the potential cluster. Hence the CH candidate with both higher residual energy and higher ECC has more possibility to be the CH. By comparing ECC, the suitable CHs can be obtained. Simulation results illustrate that ECHS protocol prolongs the network lifetime and also increases the amount of data received at BS.

  20. Further investigation of the model-independent probe of heavy neutral Higgs bosons at LHC Run 2

    Science.gov (United States)

    Kuang, Yu-Ping; Ren, Hong-Yu; Xia, Ling-Hao

    2016-02-01

    In one of our previous papers, we provided general, effective Higgs interactions for the lightest Higgs boson h (SM-like) and a heavier neutral Higgs boson H based on the effective Lagrangian formulation up to the dim-6 interactions, and then proposed two sensitive processes for probing H. We showed in several examples that the resonance peak of H and its dim-6 effective coupling constants (ECC) can be detected at LHC Run 2 with reasonable integrated luminosity. In this paper, we further perform a more thorough study of the most sensitive process, pp→ VH* → VVV, providing information about the relations between the 1σ, 3σ, 5σ statistical significance and the corresponding ranges of the Higgs ECC for an integrated luminosity of 100 fb-1. These results have two useful applications in LHC Run 2: (A) realizing the experimental determination of the ECC in the dim-6 interactions if H is found and, (B) obtaining the theoretical exclusion bounds if H is not found. Some alternative processes sensitive for certain ranges of the ECC are also analyzed. Supported by National Natural Science Foundation of China (11135003 and 11275102)

  1. Prevalence of early childhood caries among preschool children in Trivandrum and its association with various risk factors

    Directory of Open Access Journals (Sweden)

    Sobha Kuriakose

    2015-01-01

    Full Text Available Background: Early childhood caries (ECC is a severe form of dental decay with multi-factorial origin. Objectives: The aim of this cross-sectional study was to determine the prevalence and related risk factors of ECC among preschool children residing in rural and urban areas of Trivandrum district in Kerala. Methods: A sample size of 1329 preschool children of <60 months of age was randomly selected from rural and urban areas of Trivandrum and decayed missing filled teeth indices were recorded. A standardized questionnaire was distributed to the parents. The data were subjected to SPSS version 16 and statistically analyzed with Chi-square test. Results: Prevalence of ECC in the study sample was found to be 54%. Furthermore, a positive association was obtained between ECC and age of the child, location of residence, dietary habits, and oral hygiene habits. Conclusion: There is an urgent need to implement preventive and curative oral health programs for preschool children in rural and urban areas.

  2. Pop / Mart Kuldkepp

    Index Scriptorium Estoniae

    Kuldkepp, Mart

    2007-01-01

    Heliplaatidest: Korn "Untitled", Editors "An End Has A Start", Dinosaur Jr "Beyond", Paul McCartney "Ecce Cor Meum - Behold My Heart" ja "Memory Almost Full, James Pennington presents Dark Energy "Collided Energy", Yeah Yeah Yeahs "Is Is EP", Talib Kweli"Eardrum"

  3. ROSA-III double-ended break test series for a loss-of-coolant accident in a boiling water reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tasaka, K.; Anoda, Y.; Koizumi, Y.; Kumamaru, H.; Nakamura, H.; Shiba, M.; Suzuki, M.; Yonomoto, T.

    1985-01-01

    The Rig of Safety Assessment (ROSA) III facility is a volumetrically scaled (1/424) boiling water reactor (BWR) system with an electrically heated core designed for integral loss-of-coolant accident (LOCA) and emergency-core-cooling-system (ECCS) tests. Experimental results obtained so far confirm that the severest single failure assumption in ECCS is the high-pressure core spray system failure even in a large-break LOCA in a BWR. The measured peak cladding temperature was well below the present safety criterion of 1473 K, even with the single failure assumption in ECCS, and the effectiveness of ECCS for core cooling during a double-ended-break LOCA has been confirmed. The overall agreement between the results calculated by the RELAP4/MOD6/U4/J3 computer code and the experimental results is good. The similarity between the ROSA-III test and a BWR LOCA has been confirmed through the comparison of calculated results for the ROSA-III facility and a BWR system.

  4. Diagnostic value of performing endocervical curettage at the time of colposcopy procedure; a systematic review

    Directory of Open Access Journals (Sweden)

    Shabnam Imannezhad

    2016-03-01

    Full Text Available Introduction: The importance of high-grade cervical intraepithelial neoplasia (CIN as a precursor to invasive cervical cancer suggests a considerable need for accurate screening of the patients for the risk of these lesions. This systematic review aimed to study the diagnostic significance of endocervical curettage (ECC at the time of colposcopy in the detection of CIN 2, 3, and preinvasive lesions.Methods: PubMed was searched to obtain the relevant articles based on the following search term: (endocervical curettage OR ECC AND colposcopy. The most relevant articles were included after studying the title, abstract, and full text of the obtained articles at initial search. Only English language articles published after 1992 with at least 500 patients were included in this study.Result: Among 300 articles identified by the first search, only seven articles were in line with the purpose of this systematic review. Majority of the included studies were retrospective observational studies.Conclusion: Performing ECC has higher sensitivity in women older than 40 years and those with unsatisfactory colposcopy results. However exact diagnostic usefulness of ECC at the time of colposcopy needs to be investigated in further studies.

  5. Leucocyte depletion in a drowning victim during rewarming with extracorporeal circulation may limit pulmonary oedema

    NARCIS (Netherlands)

    Vermeijden, Wytze J.; de Vries, Hans; Kieboom, Joke; Waterbolk, Tjalling

    2006-01-01

    We report two drowning victims with hypothermic circulatory arrest who were resuscitated with the use of extracorporeal circulation (ECC). The first patient developed severe post-bypass pulmonary oedema and inspired us to use a leucocyte-depletion filter in the second patient to attenuate

  6. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 145 of 145 ... Vol 21, No 2 (2013), Preventing HIV/AIDS through education: the role of ... Vol 16, No 1 (2008), Psychiatric morbidity among dental patients ... Vol 16, No 2 (2008), Risk factors associated with early childhood caries (ECC) ...

  7. Implementing Total Quality Management at El Camino College.

    Science.gov (United States)

    Gonzales, Frank S.

    The California Community Colleges are in the midst of a reform process initiated by Assembly Bill 1725. A major goal of the bill is to fund colleges' staff development efforts. In an effort to transform the campus organizational culture from one of predominant competitiveness to collaboration, El Camino College (ECC) in Torrance, California,…

  8. Effects of repeated concentric and eccentric contractions on tendon blood circulation.

    Science.gov (United States)

    Kubo, K

    2015-06-01

    Previous studies demonstrated that treatment involving eccentric training was effective in the conservative management of chronic tendinosis. However, the mechanisms for these phenomena are unknown. The purpose of this study was to compare changes in blood circulation of the tendons after the repeated concentric and eccentric contractions. 11 healthy males volunteered for this study. Subjects performed the repeated concentric (CON) and eccentric (ECC) contractions (5 sets of 10 maximal voluntary contractions) of the plantar flexors. During and after repeated contractions, oxyhemoglobin (Oxy), deoxyhemoglobin (Deoxy), total hemoglobin (THb), and oxygen saturation (StO2) of the Achilles tendons were measured using red laser lights. Oxy and THb increased during and after ECC, but not CON. Deoxy decreased during both CON and ECC. Increase in StO2 during and after ECC was greater than that during and after CON. These results suggested that changes in blood circulation of the Achilles tendon during and after repeated eccentric contractions were more remarkable than those during and after repeated concentric contractions.

  9. Resource efficiency of hardware extensions of a 4-issue VLIW processor for elliptic curve cryptography

    Science.gov (United States)

    Jungeblut, T.; Puttmann, C.; Dreesen, R.; Porrmann, M.; Thies, M.; Rückert, U.; Kastens, U.

    2010-12-01

    The secure transmission of data plays a significant role in today's information era. Especially in the area of public-key-cryptography methods, which are based on elliptic curves (ECC), gain more and more importance. Compared to asymmetric algorithms, like RSA, ECC can be used with shorter key lengths, while achieving an equal level of security. The performance of ECC-algorithms can be increased significantly by adding application specific hardware extensions. Due to their fine grained parallelism, VLIW-processors are well suited for the execution of ECC algorithms. In this work, we extended the fourfold parallel CoreVA-VLIW-architecture by several hardware accelerators to increase the resource efficiency of the overall system. For the design-space exploration we use a dual design flow, which is based on the automatic generation of a complete C-compiler based tool chain from a central processor specification. Using the hardware accelerators the performance of the scalar multiplication on binary fields can be increased by the factor of 29. The energy consumption can be reduced by up to 90%. The extended processor hardware was mapped on a current 65 nm low-power standard-cell-technology. The chip area of the CoreVA-VLIW-architecture is 0.24 mm2 at a power consumption of 29 mW/MHz. The performance gain is analyzed in respect to the increased hardware costs, as chip area or power consumption.

  10. Training of Paraeducators for Physical Education for Children with Visual Impairments

    Science.gov (United States)

    Lieberman, Lauren J.; Conroy, Paula

    2013-01-01

    Introduction: Children with visual impairments are often behind their peers in physical and motor skills. It is often necessary for these children to work one to one with a paraeducator to gain the benefits of physical education, improve physical activity and motor skills, and attain the basic standards of the Expanded Core Curriculum (ECC).…

  11. Resistance to Erwina spp. in potato (Solanum tuberosum L.).

    NARCIS (Netherlands)

    Allefs, J.J.H.M.

    1995-01-01

    Blackleg is a disease of potato, Solanum tuberosum , which is caused by the bacteria Erwinia carotovora subsp. carotovora ( Ecc ), E.c. subsp. atroseptica ( Eca ) or E . chrysanthemi (Ech). Incidence of blackleg negatively affects the quality of seed potatoes. Disease control relies on phytosanitary

  12. The behavioral approach as a paradigm for modeling interconnected systems

    NARCIS (Netherlands)

    Trentelman, HL; Willems, JC

    2003-01-01

    This article contains the outline of a 3-h course that will be given by the authors at the ECC 2003. The course consists of four parts: 1. The basic concepts, 2. Linear differential systems, 3. Control in a behavioral setting, and 4. The synthesis of dissipative systems.

  13. A Hardware-Accelerated ECDLP with High-Performance Modular Multiplication

    Directory of Open Access Journals (Sweden)

    Lyndon Judge

    2012-01-01

    Full Text Available Elliptic curve cryptography (ECC has become a popular public key cryptography standard. The security of ECC is due to the difficulty of solving the elliptic curve discrete logarithm problem (ECDLP. In this paper, we demonstrate a successful attack on ECC over prime field using the Pollard rho algorithm implemented on a hardware-software cointegrated platform. We propose a high-performance architecture for multiplication over prime field using specialized DSP blocks in the FPGA. We characterize this architecture by exploring the design space to determine the optimal integer basis for polynomial representation and we demonstrate an efficient mapping of this design to multiple standard prime field elliptic curves. We use the resulting modular multiplier to demonstrate low-latency multiplications for curves secp112r1 and P-192. We apply our modular multiplier to implement a complete attack on secp112r1 using a Nallatech FSB-Compute platform with Virtex-5 FPGA. The measured performance of the resulting design is 114 cycles per Pollard rho step at 100 MHz, which gives 878 K iterations per second per ECC core. We extend this design to a multicore ECDLP implementation that achieves 14.05 M iterations per second with 16 parallel point addition cores.

  14. Early Childhood Care and Education and Other Family Policies and Programs in South-East Asia. Early Childhood and Family Policy Series.

    Science.gov (United States)

    Kamerman, Sheila B.

    This report describes early childhood care and education (ECCE) and other family support policies and programs in seven southeast Asian countries: Thailand, Malaysia, Philippines, Indonesia, Vietnam, Laos, and Cambodia. The report draws primarily on background country reports prepared by officials in these countries to focus on the context in…

  15. Advances in the microbial etiology and pathogenesis of early childhood caries.

    Science.gov (United States)

    Hajishengallis, E; Parsaei, Y; Klein, M I; Koo, H

    2017-02-01

    Early childhood caries (ECC) is one of the most prevalent infectious diseases affecting children worldwide. ECC is an aggressive form of dental caries, which, left untreated, can result in rapid and extensive cavitation in teeth (rampant caries) that is painful and costly to treat. Furthermore, it affects mostly children from impoverished backgrounds, and so constitutes a major challenge in public health. The disease is a prime example of the consequences arising from complex, dynamic interactions between microorganisms, host, and diet, leading to the establishment of highly pathogenic (cariogenic) biofilms. To date, there are no effective methods to identify those at risk of developing ECC or to control the disease in affected children. Recent advances in deep-sequencing technologies, novel imaging methods, and (meta)proteomics-metabolomics approaches provide an unparalleled potential to reveal new insights to illuminate our current understanding about the etiology and pathogenesis of the disease. In this concise review, we provide a broader perspective about the etiology and pathogenesis of ECC based on previous and current knowledge on biofilm matrix, microbial diversity, and host-microbe interactions, which could have direct implications for developing new approaches for improved risk assessment and prevention of this devastating and costly childhood health condition. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  16. Factors associated with the risk of caries development after comprehensive dental rehabilitation under general anesthesia

    Directory of Open Access Journals (Sweden)

    Yai-Tin Lin

    2016-06-01

    Conclusion: This study has shown that SM count and CRA score were associated with new caries development in ECC children who needed to be treated under general anesthesia. The modified Cariogram used in this study is another significant tool for predicting new carries development in this particular population.

  17. Social and Behavioral Determinants for Early Childhood Caries among Preschool Children in India

    Directory of Open Access Journals (Sweden)

    Mitali Jain

    2015-06-01

    Full Text Available Background and aims. Early Childhood Caries (ECC is a public health problem with biological, social and behavioural determinants and the notion that the principal etiology is inappropriate feeding modalities is no longer tenable. Hence this study was undertaken to assess the relationship between ECC and socio-demographic factors, dietary habits, oral hygiene habits and parental characteristics. Materials and methods. The study involved a dental examination of 1400 children aged 0‒71 months, recording caries using Gruebbel’s deft index and a structured questionnaire to interview parents or caretakers. The tabulated data was statis-tically analyzed using t-test and ANOVA at 5% level of significance. Results. The variables significantly associated with ECC were age (P0.05. Conclusion. ECC is preventable and manageable with proper information and skills. It is important for healthcare profes-sionals, family physicians and parents to be cognizant of the involved risk factors as their preventive efforts represent the first line of defense.

  18. The association between oral hygiene behavior and knowledge of caregivers of children with severe early childhood caries

    Directory of Open Access Journals (Sweden)

    Ru-Shing Tang

    2014-09-01

    Conclusion: Poor oral hygiene behavior and the knowledge of caregivers are associated with dental hygiene behavior of children with S-ECC. However, such education should be directed toward those with a lower level of education and lower socio-economic status.

  19. Risk factors of early childhood caries in a Southeast Asian population.

    NARCIS (Netherlands)

    Palenstein Helderman, W.H. van; Soe, W.; Hof, M.A. van 't

    2006-01-01

    A retrospective cohort study on ECC and associated factors was conducted among mothers with 25- to 30-month-old infants in a community where prolonged breastfeeding was common practice. All infants who consumed sugary supplementary food or rice that was pre-chewed by the mother, or who fell asleep

  20. Knowledge, practice, and training of pediatricians about early childhood caries in Bhubaneswar

    Directory of Open Access Journals (Sweden)

    Sonali Mallick

    2016-01-01

    Full Text Available Introduction: Early childhood caries (ECC is one of the rapidly emerging oral health problems requiring anticipatory guidance. Pediatricians are in the unique and ideal position to advice parents about the prevention and treatment of ECC in their children. Aim: To assess the knowledge, practices, and training regarding ECC and infant oral health care among pediatricians in Bhubaneswar city, Odisha, India. Materials and Methods: A cross-sectional study was conducted among 100 pediatricians in Bhubaneswar city using a self-administered questionnaire. Analysis of variance and Student's t-test were used to find the significance of study parameters. Any value ≤0.05 was considered to be statistically significant. Results: Knowledge about ECC and child oral health was found to be significantly higher among male pediatricians (P = 0.03 and those practicing in urban localities (P = 0.007. Confidence of diagnosing (P = 0.006 and practice patterns (P = 0.003 was found to be significantly higher with increasing hours of patient care per week. Conclusions: Most of the pediatricians had better knowledge were confident and performed better practices.

  1. Research on Secure Authentication Mechanism of Grid

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    Based on the analysis on the security mechanism of grid, this paper discusses the advantages of latest techniques of grid security, and presents a secure authentication scheme of grid based on elliptic curve cryptosystem (ECC). The secure authentication scheme may provide reference value for the further application of grid.

  2. Early Childhood Dental Caries. Building Community Systems for Young Children.

    Science.gov (United States)

    Platt, Laurence J.; Cabezas, Maritza C.

    As part of a series of reports designed to support the implementation of Proposition 10: The California Children and Families Act and to provide comprehensive and authoritative information on critical issues concerning young children and families in California, this report describes the scope and severity of early childhood caries (ECC), a…

  3. Enhancement of salinity tolerance in wheat through soil applied calcium carbide

    Directory of Open Access Journals (Sweden)

    Z. Ahmad

    2009-05-01

    Full Text Available Calcium carbide (CaC2 has been reported to increase growth and yield of crops under normal soil conditions. This study assessed its capacity to enhance salinity tolerance in wheat (Triticum aestivum L.; cv- 1076 under saline conditions. Three levels of salinity: 0, 7 and 12 dS m-1 were created using NaCl. Nitrogen, phosphorus and potassium were applied as ammonium sulphate and KH2PO4 at 50 and 25 mg kg-1 soil, respectively. The encapsulated calcium carbide (ECC at 45 mg kg-1 soil produced 1291.8 µmols of acetylene (C2H2 and 257.5 µmols of its product ethylene (C2H4 over a period of 80 days. The results of the pot study indicated that ECC increased the weight of spike, weight of grains per spike, length of spike, total water concentration, root/shoot ratio and relative leaf water content up to 17, 23, 22, 35, 33 and 3%, respectively, over the control. Contrary to this, salinity (at 12 dS m -1 decreased all these parameters up to 68, 60, 26, 30, 28 and 8%, respectively, compared to the control. These results indicate that ECC enhances salinity tolerance in wheat by improving uptake of nutrients through enhanced root growth, increased hydraulic conductivity and hormonal action of ethylene released by ECC. Total water concentration was positively correlated (0.73 with grains spike-1 at P ≤ 0.05

  4. Outcomes after contemporary Fontan operation : Step by step

    NARCIS (Netherlands)

    S.S.M. Bossers (Sjoerd)

    2015-01-01

    markdownabstractAims and outline of this thesis The aim of this thesis was to study medium to long term outcome in a large contemporary cohort of Fontan patients. These are patients that have been operated upon according to a modern technique (either ILT or ECC TCPC) in a staged manner. Furthermo

  5. Risk factors for predicting early childhood caries in Anganwadi children in Bangalore city: A cross-sectional study

    Directory of Open Access Journals (Sweden)

    K B Shilpashree

    2016-01-01

    Full Text Available Introduction: Preschool oral health is an overlooked aspect of childhood health and well-being. Early childhood caries (ECC is an infectious and multifactorial disease of the childhood. Several factors play a role in the etiology of disease. Aim: To predict the risk factors for occurrence of ECC in children aged 3–6 years of Anganwadi centers. Materials and Methods: A cross-sectional descriptive study consisting of 3009 children aged 3–6 years attending Anganwadi centers of Bangalore South. Required and relevant information regarding feeding practices and oral hygiene practices were obtained. Multivariate regression analysis was performed for statistical analysis. Results: The prevalence of ECC was 31.4% with mean decayed, missing, and filled teeth (DMFT of study population is 1.15 ± 2.28. Mean DMFT among males and females were 1.31 ± 2.48 and 1.01 ± 2.07, respectively. Habit of bottle feeding in the night (P < 0.001 and odds ratio [OR] of 1.32, in between meal, snacks (P < 0.001 and OR of 1.24 were the risk factors for caries in this study. Conclusions: The present study provides an insight regarding the risk factors involved in predicting ECC in children.

  6. 77 FR 52765 - Dominion Nuclear Connecticut, Inc. Millstone Power Station, Unit 3; Exemption

    Science.gov (United States)

    2012-08-30

    ... Millstone Power Station Unit 1, a permanently defueled boiling water reactor nuclear unit, and Millstone...-water nuclear power reactors,'' requires that each power reactor meet the acceptance criteria for ECCS... Reactions at High Temperatures, III. Experimental and Theoretical Studies of the Zirconium-Water...

  7. AB 1725 Human Development Resources Plan, 1989-1990. El Camino Community College District.

    Science.gov (United States)

    El Camino Community Coll. District, Torrance, CA.

    The staff development plan presented in this paper was developed in 1989 at El Camino College (ECC) in compliance with California Assembly Bill (AB) 1725. The first sections describe how AB 1725 funding will be used to enhance staff development at the college, report the results of several needs assessment activities conducted to determine the…

  8. The Introduction of the Cooperative English Test at El Camino College.

    Science.gov (United States)

    Garlock, Jerry C.

    In accordance with an English Department decision to change from the Purdue English Placement Test to the Cooperative English Test, the Research Office of El Camino College (ECC) coordinated changes for scoring and computer operations while attempting to maintain the existing student placement system, preserve the ratio of students assigned to the…

  9. Early Childhood Education and Care in Ireland: Getting it Right for Children

    OpenAIRE

    Hayes, Noirin; Bradley, Siobhan

    2008-01-01

    Seminar proceedings edited by Noirin Hayes and Siobhan Bradley. Contains two presentations: Beyond Childcare, Markets and Technical Practice – or Repoliticising Early Childhood by Peter Moss; Irish Approaches to ECCE – Keeping Politics Out of the Nursery by Maura Adshead & Gerardine Neylon.

  10. Acute effects of stretching on muscle stiffness after a bout of exhaustive eccentric exercise.

    Science.gov (United States)

    Torres, R; Appell, H-J; Duarte, J A

    2007-07-01

    With the aim to analyze the influence of stretching on muscle stiffness after eccentric exercise, 30 young men (18 - 32 years old), were divided into three groups: STR, undergoing a stretching program (SP) of the dominant quadriceps muscle, ECC, undergoing exhaustive eccentric exercise, and ECC/STR, undergoing eccentric exercise, followed by SP. Muscle stiffness (MS) was assessed immediately before the respective programs, and 1 and 24 hours after, measuring the following parameters during Wartenberg pendulum test: angle and angular velocity of first knee flexion (FKF) and following oscillating extension, time of oscillating movements and final resting knee angle (FRKA). Despite the slight (2%) but significant increase of FRKA, all further parameters did not change over time in STR. MS in ECC was documented by the reduced range of motion (ROM) and the slower angular velocity. Reduction in FRKA (10%) was still present after 24 hours, while other variables tended to recover eventually. Similar reduction in FKF was observed for ECC/STR, but with significantly less impairment in the range of pendulum movement one hour after the exercise and in tendency still remained less impaired 24 hours after. The results suggest that SP conducted after exhaustive eccentric exercise alleviated reductions in ROM induced by exercise.

  11. Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells.

    NARCIS (Netherlands)

    Dormeyer, W.; van Hoof, D.; Braam, S.R.; Heck, A.J.R.; Mummery, C.L.; Krijgsveld, J.

    2008-01-01

    Human embryonic stem cells (hESCs) are of immense interest in regenerative medicine as they can self-renew indefinitely and can give rise to any adult cell type. Human embryonal carcinoma cells (hECCs) are the malignant counterparts of hESCs found in testis tumors. hESCs that have acquired chromosom

  12. Fire exposed steel columns with a thermal gradient over the cross-section

    NARCIS (Netherlands)

    Ojeda, O.D.; Maljaars, J.; Abspoel, R.

    2016-01-01

    Thermal gradients often occur in fire exposed structures. This paper considers thermal gradients over the cross-section of steel columns. By means of finite element simulations, the paper demonstrates that these gradients reduce the fiexural buckling resistance of the columns. This is due to the ecc

  13. 30. IV avati Tallinna Kunstihoone galeriis...

    Index Scriptorium Estoniae

    2003-01-01

    Näitusel "Ecce libri" eksponeerivad Pille Kivihall, Tiina Piisang ja Maarja Undusk installatsioone raamatutest. 13. V ümarlauavestlus raamatu saatusest ja väärtusest virtuaalvaimustuse ajastul. Osalevad Raivo Kelomees, Ilja Sundelevitsh, M. Undusk, Toomas Raudam, Jürgen Rooste, Jaan Undusk jt.

  14. The cardiac α1C subunit can support excitation-triggered Ca2+ entry in dysgenic and dyspedic myotubes

    Science.gov (United States)

    Bannister, R.A.; Beam, K.G.

    2010-01-01

    Depolarization-induced entry of divalent ions into skeletal muscle has been attributed to a process termed Excitation-Coupled Ca2+ Entry (ECCE), which is hypothesized to require the interaction of the ryanodine receptor (RyR1), the L-type Ca2+ channel (DHPR) and another unidentified cation channel. Thus, ECCE is absent in myotubes lacking either the DHPR (dysgenic) or RyR1 (dyspedic). Furthermore, ECCE, as measured by Mn2+ quench of Fura-2, is reconstituted by expression of a mutant DHPR α1S subunit (SkEIIIK) thought to be impermeable to divalent cations. Previously, we showed that the bulk of depolarization-induced Ca2+ entry could be explained by the skeletal L-type current. Accordingly, one would predict that any Ca2+ current similar to the endogenous current would restore such entry and that this entry would not require coupling to either the DHPR or RyR1. Here, we show that expression of the cardiac α1C subunit in either dysgenic or dyspedic myotubes does result in Ca2+ entry similar to that ascribed to ECCE. We also demonstrate that, when potentiated by strong depolarization and Bay K 8644, SkEIIIK supports entry of Mn2+. These results strongly support the idea that the L-type channel is the major route of Ca2+ entry in response to repetitive or prolonged depolarization of skeletal muscle. PMID:19625771

  15. The cardiac alpha(1C) subunit can support excitation-triggered Ca2+ entry in dysgenic and dyspedic myotubes.

    Science.gov (United States)

    Bannister, Roger A; Beam, Kurt G

    2009-01-01

    Depolarization-induced entry of divalent ions into skeletal muscle has been attributed to a process termed Excitation-Coupled Ca(2+) Entry (ECCE), which is hypothesized to require the interaction of the ryanodine receptor (RyR1), the L-type Ca(2+) channel (DHPR) and another unidentified cation channel. Thus, ECCE is absent in myotubes lacking either the DHPR (dysgenic) or RyR1 (dyspedic). Furthermore, ECCE, as measured by Mn(2+) quench of Fura-2, is reconstituted by expression of a mutant DHPR alpha(1S) subunit (SkEIIIK) thought to be impermeable to divalent cations. Previously, we showed that the bulk of depolarization-induced Ca(2+) entry could be explained by the skeletal L-type current. Accordingly, one would predict that any Ca(2+) current similar to the endogenous current would restore such entry and that this entry would not require coupling to either the DHPR or RyR1. Here, we show that expression of the cardiac alpha(1C) subunit in either dysgenic or dyspedic myotubes does result in Ca(2+) entry similar to that ascribed to ECCE. We also demonstrate that, when potentiated by strong depolarization and Bay K 8644, SkEIIIK supports entry of Mn(2+). These results strongly support the idea that the L-type channel is the major route of Ca(2+) entry in response to repetitive or prolonged depolarization of skeletal muscle.

  16. Tudengimaal, köited, auväärne graafika / Harry Liivrand

    Index Scriptorium Estoniae

    Liivrand, Harry, 1961-

    2003-01-01

    TÜ maalikunsti üliõpilaste näitus "Tartu kevad" Kastellaanimaja galeriis; Pille Kivihalli, Tiina Piisangu ja Maarja Unduski näitus "Ecce libris" Tallinna Kunstihoone galeriis; Eesti ja Taani graafikanäitus "Hjorring-Tallinn 2003" Hobusepea galeriis

  17. Näpuga erootikat vaatamas / Evelin Kivimaa

    Index Scriptorium Estoniae

    Kivimaa, Evelin, 1974-

    1999-01-01

    Erootika Eesti kunstisaalides: Pärnu Mudaravilas Udo Siigi joonistuste näitus; näitused 'Mees ja Naine' ja 'Ecce Homo' Pärnu Uue Kunsti Muuseumis; näitus 'Mida te loete mu prints' Kastellaanimaja galeriis; näitus 'Eros' Tallinna Kunstihoones; näitus 'Enesepaljastajad' Kunstihoone galeriis.

  18. Results of congenital cataract surgery with and without intraocular lens implantation in infants and children.

    Science.gov (United States)

    Borisovsky, Gilad; Silberberg, Gilad; Wygnanski-Jaffe, Tamara; Spierer, Abraham

    2013-09-01

    Operations for congenital cataract in children in the past had resulted in aphakia. Improvement in surgical tools and techniques as well as in intraocular lens (IOL) implantation has led to correction of the aphakia by IOL implantation. We report the outcome of cataract surgery with and without IOL on these children in our institution between 1991-2008. In this retrospective cohort study, the medical records of all children who underwent surgery for congenital cataract were reviewed. The final study group included 144 children (218 eyes). Postoperative visual acuity (VA) was tested either by Teller Acuity Cards (in preverbal children) or by the Snellen chart. Data on VA status and postoperative complications were retrieved. Patients with bilateral cataract had better postoperative VA than patients with unilateral cataract (logMAR 0.559 ± 0.455 vs. 0.919 ± 0.685, respectively, P ECCE) + IOL implantation group than in the ECCE only group (20.6 % vs. 8.3 %, respectively, P = 0.018). Patients with bilateral cataract had better postoperative VA compared with those with unilateral cataract. The type of surgery had no effect on final VA, but there was a higher rate of secondary cataract in the ECCE + IOL patients compared to the ECCE only patients.

  19. Enhanced excitation-coupled calcium entry in myotubes expressing malignant hyperthermia mutation R163C is attenuated by dantrolene.

    Science.gov (United States)

    Cherednichenko, Gennady; Ward, Chris W; Feng, Wei; Cabrales, Elaine; Michaelson, Luke; Samso, Montserrat; López, José R; Allen, Paul D; Pessah, Isaac N

    2008-04-01

    Dantrolene is the drug of choice for the treatment of malignant hyperthermia (MH) and is also useful for treatment of spasticity or muscle spasms associated with several clinical conditions. The current study examines the mechanisms of dantrolene's action on skeletal muscle and shows that one of dantrolene's mechanisms of action is to block excitation-coupled calcium entry (ECCE) in both adult mouse flexor digitorum brevis fibers and primary myotubes. A second important new finding is that myotubes isolated from mice heterozygous and homozygous for the ryanodine receptor type 1 R163C MH susceptibility mutation show significantly enhanced ECCE rates that could be restored to those measured in wild-type cells after exposure to clinical concentrations of dantrolene. We propose that this gain of ECCE function is an important etiological component of MH susceptibility and possibly contributes to the fulminant MH episode. The inhibitory potency of dantrolene on ECCE found in wild-type and MH-susceptible muscle is consistent with the drug's clinical potency for reversing the MH syndrome and is incomplete as predicted by its efficacy as a muscle relaxant.

  20. Outer Wheel Uniformity of the ElectroMagnetic Endcap Calorimeter

    CERN Document Server

    Oliver, C

    2005-01-01

    An analysis of the test beam data for the uniformity of three ECC modules is presented. A non-uniformity of less than 0.6 per cent is obtained for the outer wheel of the three modules. The results are found to be independent of the signal reconstruction method used as long as the residuals are kept below 4 per cent.