EBS Radionuclide Transport Abstraction

International Nuclear Information System (INIS)

J.D. Schreiber

2005-01-01

The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in ''Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration'' (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment for the license application (TSPA-LA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA-LA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers

EBS Radionuclide Transport Abstraction

Energy Technology Data Exchange (ETDEWEB)

J.D. Schreiber

2005-08-25

The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in ''Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration'' (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment for the license application (TSPA-LA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA-LA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport

EBS Radionuclide Transport Abstraction

Energy Technology Data Exchange (ETDEWEB)

J. Prouty

2006-07-14

The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment (TSPA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport

EBS Radionuclide Transport Abstraction

International Nuclear Information System (INIS)

J. Prouty

2006-01-01

The purpose of this report is to develop and analyze the engineered barrier system (EBS) radionuclide transport abstraction model, consistent with Level I and Level II model validation, as identified in Technical Work Plan for: Near-Field Environment and Transport: Engineered Barrier System: Radionuclide Transport Abstraction Model Report Integration (BSC 2005 [DIRS 173617]). The EBS radionuclide transport abstraction (or EBS RT Abstraction) is the conceptual model used in the total system performance assessment (TSPA) to determine the rate of radionuclide releases from the EBS to the unsaturated zone (UZ). The EBS RT Abstraction conceptual model consists of two main components: a flow model and a transport model. Both models are developed mathematically from first principles in order to show explicitly what assumptions, simplifications, and approximations are incorporated into the models used in the TSPA. The flow model defines the pathways for water flow in the EBS and specifies how the flow rate is computed in each pathway. Input to this model includes the seepage flux into a drift. The seepage flux is potentially split by the drip shield, with some (or all) of the flux being diverted by the drip shield and some passing through breaches in the drip shield that might result from corrosion or seismic damage. The flux through drip shield breaches is potentially split by the waste package, with some (or all) of the flux being diverted by the waste package and some passing through waste package breaches that might result from corrosion or seismic damage. Neither the drip shield nor the waste package survives an igneous intrusion, so the flux splitting submodel is not used in the igneous scenario class. The flow model is validated in an independent model validation technical review. The drip shield and waste package flux splitting algorithms are developed and validated using experimental data. The transport model considers advective transport and diffusive transport

The recent industrial EB applications in Japan

International Nuclear Information System (INIS)

Nakai, Koji; Kashiwagi, Masayuki; Mizusawa, Kenichi

1995-01-01

The conventional applications of electron beam processing such as, crosslinking of electric wire and cable insulations, polyethylene foam, and of rubber tire components have been the main part of the EB business for many years. New applications are continuing to appear, however, the growth of the new applications has been relatively slow. Nissin High-Voltage, as one of the worlds leading manufacturers of electron beam equipments, continues to develop and improve EB equipment to meet the requirements of these new applications. In this paper recent EB applications and its improvements are described. (author)

Using EB-QFD to achieve competitive advantages for world class manufacturing

Directory of Open Access Journals (Sweden)

Rahman Mostofi

2012-10-01

Full Text Available This paper introduces a tool named EB-QFD used for electronic business planning in strategic issues. Nowadays, the challenges of manufacturing sectors for achieving global competition will depend on their speed to change from domestic to world class manufacturing organizations, also the rapid global deployment of electronic business, information technology and their benefits have required managers to make decision, which look for a balance world class manufacturing factors with strategic business goals. To ensure that selected e-business strategies meet world class manufacturing requirements, organizations should simultaneously explore and communicate the relationship between world class manufacturing and electronic business. Electronic business planners can achieve competitive advantages through the implementation of an integration of quality function deployment (QFD with electronic business (EB called EB-QFD. This study is based on data collected from an Iranian auto parts manufacturing company and the implementation of EB-QFD. In this research, EB-QFD contains two parts named EB-WHATs as needs of Electronic Business and EB-HOWs as resources for EB-WHATs. Statistical analysis points that there are positive relationships between using EB-WHATs and EB-HOW and world class manufacturing factors as competitive advantages. We used electronic business systems for EB-WHATs and resource based view (RBV for EB-HOWs.

Antiviral activity of the EB peptide against zoonotic poxviruses

Directory of Open Access Journals (Sweden)

Altmann Sharon E

2012-01-01

Full Text Available Abstract Background The EB peptide is a 20-mer that was previously shown to have broad spectrum in vitro activity against several unrelated viruses, including highly pathogenic avian influenza, herpes simplex virus type I, and vaccinia, the prototypic orthopoxvirus. To expand on this work, we evaluated EB for in vitro activity against the zoonotic orthopoxviruses cowpox and monkeypox and for in vivo activity in mice against vaccinia and cowpox. Findings In yield reduction assays, EB had an EC50 of 26.7 μM against cowpox and 4.4 μM against monkeypox. The EC50 for plaque reduction was 26.3 μM against cowpox and 48.6 μM against monkeypox. A scrambled peptide had no inhibitory activity against either virus. EB inhibited cowpox in vitro by disrupting virus entry, as evidenced by a reduction of the release of virus cores into the cytoplasm. Monkeypox was also inhibited in vitro by EB, but at the attachment stage of infection. EB showed protective activity in mice infected intranasally with vaccinia when co-administered with the virus, but had no effect when administered prophylactically one day prior to infection or therapeutically one day post-infection. EB had no in vivo activity against cowpox in mice. Conclusions While EB did demonstrate some in vivo efficacy against vaccinia in mice, the limited conditions under which it was effective against vaccinia and lack of activity against cowpox suggest EB may be more useful for studying orthopoxvirus entry and attachment in vitro than as a therapeutic against orthopoxviruses in vivo.

UV/EB curing in Australia

International Nuclear Information System (INIS)

Woods, R.; Garnett, J.; Loo Teck Ng

1999-01-01

Progress in LTV/EB curing is reviewed in Australia. Generally the technology is used by those industries where curing is well developed in Europe and North America, however the scale is an order of magnitude lower due to the smaller market size. The Asian economic crisis does not appear to have affected expansion of the technology in Australia. EB continues to be successfully used in the packaging and foam fields whilst in UV, security devices, particularly banknotes are steadily expanding especially in export markets have been studied

Revised design for the Tokamak experimental power reactor

International Nuclear Information System (INIS)

Stacey, W.M. Jr.; Abdou, M.A.; Brooks, J.N.

1977-03-01

A new, preliminary design has been identified for the tokamak experimental power reactor (EPR). The revised EPR design is simpler, more compact, less expensive and has somewhat better performance characteristics than the previous design, yet retains many of the previously developed design concepts. This report summarizes the principle features of the new EPR design, including performance and cost

UV and EB radiation processing in developing countries

International Nuclear Information System (INIS)

Garnett, J.L.

1991-01-01

Ultraviolet and electron beams (EB) are to be considered as complementary technologies in the radiation processing field. In many countries, UV processing is used as the pathfinder for EB. In the developing countries the decision to adopt radiation processing techniques to choose between UV and EB will largely be determined by economics, the availability of the chemists and also skilled personnel to service both lines and equipment. (orig./A.B.)

Revised MITG design, fabrication procedure, and performance predictions

International Nuclear Information System (INIS)

Schock, A.

1983-01-01

The design, analysis, and key features of the Modular Isotopic Thermoelectric Generator (MITG) were described in a 1981 IECEC paper; and the design, fabrication, testing, and post-test analysis of test assemblies simulating prototypical MITG modules were described in preceding papers in these proceedings. These analyses succeeded in identifying and explaining the principal causes of thermal-stress problems encountered in the tests, and in confirming the effectiveness of design changes for alleviating them. The present paper presents additional design improvements for solving these and other problems, and describes new thermoelectric material properties generated by independent laboratories over the past two years. Based on these changes and on a revised fabrication procedure, it presents a reoptimization of the MITG design and computes the power-to-weight ratio for the revised design. That ratio is appreciably lower than the 1981 prediction, primarily because of changes in material properties; but it is still much higher than the specific power of current-generation RTGs

EB-PVD process management for highly productive zirconia thermal barrier coating of turbine blades

International Nuclear Information System (INIS)

Reinhold, E.; Botzler, P.; Deus, C.

1999-01-01

Zirconia thermal barrier coatings are well used in the turbine manufacturing industry because they ensure extended lifetimes of turbine blades. Compared with other techniques, EB-PVD processes are best suited for the deposition on turbine blades with regard to the layer properties. Therefore EB-PVD coaters for turbine blades are becoming increasingly interesting. The coating costs per component are mainly dependent on a highly productive solution for the deposition task. Thus the EB-PVD process management has to be optimized in order to meet the productivity requirements of the manufacturers. This includes the requirement of high deposition rates, large deposition areas, long time stable production cycles as well as a matched duration of preheating, deposition and cooling down per charge. Modern EB-PVD solutions to be introduced allow deposition rates on blades up to 7 μm/min. The consequences for the technological process management and plant design concerning long time stable coating cycles with high productivity will be discussed. (orig.)

EB-curing of coatings on wood composite boards

International Nuclear Information System (INIS)

Czvikovszky, T.; Czajlic, I.; Takacs, E.; Ille, A.; Salleh, N.G.; Alpar, T.

1988-01-01

The industrial radiation processing using low energy electron beam (EB) accelerators lower than 300 keV offers high speed, safe technologies for the chemical conversion of thin layer coatings. Because of the nonselective mode of initiating chain reaction polymerization involving free radicals in synthetic coating layers and suitable substrates, the EB curing of the coatings on woods and papers has particular advantage. Hungary decided to start an up-to-date EB line to process cement-bound (CB) wood chipboards with pigmented acrylic coatings. The CB wood chipboards contain more than 60 % of portland cement and up to 40 % of wood particles. They are produced as large boads of 6 - 16 mm thickness. In their fireproof character and other aspects, they are similar to asbestos-cement boards without containing carcinagenic asbestos, and are stable against moisture and atmospheric influences. EB-cured acrylate coating improved further those properties, and makes them valuable structural material. Oligomers and monomers as the main components of EB curable coatings, the irradiation with a Van de Graaff type electron accelerator of 2 MeV and the results are reported. The oligomers play the most important role in the formation of radiation curable coatings. (K.I.)

77 FR 38124 - Inspector General; Line of Succession Designation, No. 23-C, Revision 5

Science.gov (United States)

2012-06-26

... SMALL BUSINESS ADMINISTRATION Inspector General; Line of Succession Designation, No. 23-C, Revision 5 This document replaces and supersedes ``Delegation of Authority and Line of Succession No. 23-C, Revision 4.'' Line of Succession Designation, No. 23-C, Revision 5: Effective immediately, the Inspector...

UV/EB curable psa's

International Nuclear Information System (INIS)

Glotfelter, C.A.

1995-01-01

The author describe both water-based and 100% solids UV/EB curable PSA's (Pressure Sensitive Adhesives) and their properties. A new acrylate monomer, ethoxylated nonyl phenol acrylate, has great utility in the formulation of water-based PSA's

Designing Automated Guidance to Promote Productive Revision of Science Explanations

Science.gov (United States)

Tansomboon, Charissa; Gerard, Libby F.; Vitale, Jonathan M.; Linn, Marcia C.

2017-01-01

Supporting students to revise their written explanations in science can help students to integrate disparate ideas and develop a coherent, generative account of complex scientific topics. Using natural language processing to analyze student written work, we compare forms of automated guidance designed to motivate productive revision and help…

Review of revised Japanese seismic guidelines for Nuclear Power Plant design

International Nuclear Information System (INIS)

Kato, M.

1987-01-01

Development of aseismic design for nuclear power plants in Japan has evolved roughly in three stages. The first phase, which continued by 1978, was a period progressive development when design for each siteplant has referred to designs of predecessor plants and have added the latest knowledge and experience in that time. The second phase from issuance of 'Regulatory Guide for Aseismic Design of Nuclear Power Reactor Facilities' (1978, revised in 1981), or 1978 to 1986, was a period when the application of customary conservative design method was continued, while standardization of the aseismic design technology have been proceded. It is in this phase when new knowledge was accumulated by aseismic proof studies. The third phase represents a transient period to rational design when the conservative aseismic design technology has been reviewed due to the new knowledge and revision of the above JEAG guideline has progressed for incorporation in design, and ont the other hand by-laws of the Ministry of International Trade and Industry are being provided. In this report a review is given of aseismic design and its guideline after the second phase onward and an overview of the revised JEAG - Recent Aseismic Design Method - and the by-laws including rationalization of aseismic design technology

EB application in pressure sensitive adhesives

International Nuclear Information System (INIS)

Hisashi Itoh; Ichiro Enomoto

1999-01-01

Two kinds of pressure sensitive adhesives (PSA's), that were formulations of radiation cross-linkable styrene-isoprene block copolymer (SIS) and complete hydrogenated aliphatic tackifying resin or non-hydrogenated, were prepared and the electron beam (EB) irradiation effect on these PSA performances such as peel strength against some kinds of adherends was studied. The results from measuring of PSA performance exhibit the close correlation between EB irradiation effect of these and the miscibility of the tackifying resin against SIS. Further it was clarified that PSA performance was influenced by the surface tension of adherends

Thermal Conductivity of EB-PVD Thermal Barrier Coatings Evaluated by a Steady-State Laser Heat Flux Technique

Science.gov (United States)

Zhu, Dongming; Miller, Robert A.; Nagaraj, Ben A.; Bruce, Robert W.

2000-01-01

The thermal conductivity of electron beam-physical vapor deposited (EB-PVD) Zr02-8wt%Y2O3 thermal barrier coatings was determined by a steady-state heat flux laser technique. Thermal conductivity change kinetics of the EB-PVD ceramic coatings were also obtained in real time, at high temperatures, under the laser high heat flux, long term test conditions. The thermal conductivity increase due to micro-pore sintering and the decrease due to coating micro-delaminations in the EB-PVD coatings were evaluated for grooved and non-grooved EB-PVD coating systems under isothermal and thermal cycling conditions. The coating failure modes under the high heat flux test conditions were also investigated. The test technique provides a viable means for obtaining coating thermal conductivity data for use in design, development, and life prediction for engine applications.

Nanograined Net-Shaped Fabrication of Rhenium Components by EB-PVD

International Nuclear Information System (INIS)

Singh, Jogender; Wolfe, Douglas E.

2004-01-01

Cost-effective net-shaped forming components have brought considerable interest into DoD, NASA and DoE. Electron beam physical vapor deposition (EB-PVD) offers flexibility in forming net-shaped components with tailored microstructure and chemistry. High purity rhenium (Re) components including rhenium-coated graphite balls, Re- plates and tubes have been successfully manufactured by EB-PVD. EB-PVD Re components exhibited sub-micron and nano-sized grains with high hardness and strength as compared to CVD. It is estimated that the cost of Re components manufactured by EB-PVD would be less than the current CVD and powder-HIP Technologies

New surface modification method of bio-titanium alloy by EB polishing

International Nuclear Information System (INIS)

Okada, Akira; Uno, Yoshiyuki; Iio, Atsuo; Fujiwara, Kunihiko; Doi, Kenji

2008-01-01

A new surface modification for bio-titanium alloy products by electron beam (EB) polishing is proposed. In this EB polishing method, high energy density EB can be irradiated without concentrating the beam. Therefore, large-area EB with a maximum diameter of 60 mm can be used for instantaneously melting or evaporating metal surface. Experimental results made it clear that surface characteristics, such as repellency, corrosion resistance and coefficient of friction could be improved simultaneously with the surface smoothing in a few minutes under a proper condition. Therefore, EB polishing method has a possibility of high efficient surface smoothing and surface modification process for bio-titanium alloy. (author)

Reactive Transport and Coupled THM Processes in Engineering Barrier Systems (EBS)

International Nuclear Information System (INIS)

Steefel, Carl; Rutqvist, Jonny; Tsang, Chin-Fu; Liu, Hui-Hai; Sonnenthal, Eric; Houseworth, Jim; Birkholzer, Jens

2010-01-01

Geological repositories for disposal of high-level nuclear wastes generally rely on a multi-barrier system to isolate radioactive wastes from the biosphere. The multi-barrier system typically consists of a natural barrier system, including repository host rock and its surrounding subsurface environment, and an engineering barrier system (EBS). EBS represents the man-made, engineered materials placed within a repository, including the waste form, waste canisters, buffer materials, backfill and seals (OECD, 2003). EBS plays a significant role in the containment and long-term retardation of radionuclide release. EBS is involved in complex thermal, hydrogeological, mechanical, chemical and biological processes, such as heat release due to radionuclide decay, multiphase flow (including gas release due to canister corrosion), swelling of buffer materials, radionuclide diffusive transport, waste dissolution and chemical reactions. All these processes are related to each other. An in-depth understanding of these coupled processes is critical for the performance assessment (PA) for EBS and the entire repository. Within the EBS group of Used Fuel Disposition (UFD) Campaign, LBNL is currently focused on (1) thermal-hydraulic-mechanical-chemical (THMC) processes in buffer materials (bentonite) and (2) diffusive transport in EBS associated with clay host rock, with a long-term goal to develop a full understanding of (and needed modeling capabilities to simulate) impacts of coupled processes on radionuclide transport in different components of EBS, as well as the interaction between near-field host rock (e.g., clay) and EBS and how they effect radionuclide release. This final report documents the progress that LBNL has made in its focus areas. Specifically, Section 2 summarizes progress on literature review for THMC processes and reactive-diffusive radionuclide transport in bentonite. The literature review provides a picture of the state-of-the-art of the relevant research areas

Reactive Transport and Coupled THM Processes in Engineering Barrier Systems (EBS)

Energy Technology Data Exchange (ETDEWEB)

Steefel, Carl; Rutqvist, Jonny; Tsang, Chin-Fu; Liu, Hui-Hai; Sonnenthal, Eric; Houseworth, Jim; Birkholzer, Jens

2010-08-31

Geological repositories for disposal of high-level nuclear wastes generally rely on a multi-barrier system to isolate radioactive wastes from the biosphere. The multi-barrier system typically consists of a natural barrier system, including repository host rock and its surrounding subsurface environment, and an engineering barrier system (EBS). EBS represents the man-made, engineered materials placed within a repository, including the waste form, waste canisters, buffer materials, backfill and seals (OECD, 2003). EBS plays a significant role in the containment and long-term retardation of radionuclide release. EBS is involved in complex thermal, hydrogeological, mechanical, chemical and biological processes, such as heat release due to radionuclide decay, multiphase flow (including gas release due to canister corrosion), swelling of buffer materials, radionuclide diffusive transport, waste dissolution and chemical reactions. All these processes are related to each other. An in-depth understanding of these coupled processes is critical for the performance assessment (PA) for EBS and the entire repository. Within the EBS group of Used Fuel Disposition (UFD) Campaign, LBNL is currently focused on (1) thermal-hydraulic-mechanical-chemical (THMC) processes in buffer materials (bentonite) and (2) diffusive transport in EBS associated with clay host rock, with a long-term goal to develop a full understanding of (and needed modeling capabilities to simulate) impacts of coupled processes on radionuclide transport in different components of EBS, as well as the interaction between near-field host rock (e.g., clay) and EBS and how they effect radionuclide release. This final report documents the progress that LBNL has made in its focus areas. Specifically, Section 2 summarizes progress on literature review for THMC processes and reactive-diffusive radionuclide transport in bentonite. The literature review provides a picture of the state-of-the-art of the relevant research areas

Engineered Barrier System performance requirements systems study report. Revision 02

International Nuclear Information System (INIS)

Balady, M.A.

1997-01-01

This study evaluates the current design concept for the Engineered Barrier System (EBS), in concert with the current understanding of the geologic setting to assess whether enhancements to the required performance of the EBS are necessary. The performance assessment calculations are performed by coupling the EBS with the geologic setting based on the models (some of which were updated for this study) and assumptions used for the 1995 Total System Performance Assessment (TSPA). The need for enhancements is determined by comparing the performance assessment results against the EBS related performance requirements. Subsystem quantitative performance requirements related to the EBS include the requirement to allow no more than 1% of the waste packages (WPs) to fail before 1,000 years after permanent closure of the repository, as well as a requirement to control the release rate of radionuclides from the EBS. The EBS performance enhancements considered included additional engineered components as well as evaluating additional performance available from existing design features but for which no performance credit is currently being taken

Engineered Barrier System performance requirements systems study report. Revision 02

Energy Technology Data Exchange (ETDEWEB)

Balady, M.A.

1997-01-14

This study evaluates the current design concept for the Engineered Barrier System (EBS), in concert with the current understanding of the geologic setting to assess whether enhancements to the required performance of the EBS are necessary. The performance assessment calculations are performed by coupling the EBS with the geologic setting based on the models (some of which were updated for this study) and assumptions used for the 1995 Total System Performance Assessment (TSPA). The need for enhancements is determined by comparing the performance assessment results against the EBS related performance requirements. Subsystem quantitative performance requirements related to the EBS include the requirement to allow no more than 1% of the waste packages (WPs) to fail before 1,000 years after permanent closure of the repository, as well as a requirement to control the release rate of radionuclides from the EBS. The EBS performance enhancements considered included additional engineered components as well as evaluating additional performance available from existing design features but for which no performance credit is currently being taken.

A revision of the cask designers guide for the '90s

International Nuclear Information System (INIS)

Shappert, L.B.; Green, V.M.

1993-01-01

DOE has requested that ORNL initiate a revision to NSIC-68, A Guide for the Design, Fabrication, and Operation of Shipping Casks for Nuclear Applications, commonly called the Cask Designers Guide. This revision, called the Cask Handbook, has two goals: (1) to improve the quality of SARPs that are submitted to DOE, and (2) to provide up-to-date information on the design of spent fuel shipping casks, including information on fabrication, quality assurance, SARP preparation, certification, use, maintenance, and other general topics. The revision provides guidance that will help engineers through the cask licensing process, in part, by providing as much regulator-approved data and 'lessons-learned' information as possible. The effort is sponsored by DOE-Environmental, Safety and Health (EH), guided by Transportation Technology staff members at ORNL, and the information is being generated by experts in the various technical fields. (J.P.N.)

EB1 is required for primary cilia assembly in fibroblasts

DEFF Research Database (Denmark)

Schrøder, Jacob M; Schneider, Linda; Christensen, Søren T

2007-01-01

EB1 is a small microtubule (MT)-binding protein that associates preferentially with MT plus ends and plays a role in regulating MT dynamics. EB1 also targets other MT-associated proteins to the plus end and thereby regulates interactions of MTs with the cell cortex, mitotic kinetochores, and diff...... that localization of EB1 at the centriole/basal body is required for primary cilia assembly in fibroblasts....

Revised conceptual designs for the FMDP MOX fresh fuel transport package

International Nuclear Information System (INIS)

Ludwig, S.B.; Michelhaugh, R.D.; Shappert, L.B.; Chae, S.M.; Tang, J.S.

1998-03-01

The revised conceptual designs described in this document provide a foundation for the development and certification of final transport package designs that will be needed to support the disposition of surplus weapons-grade plutonium as mixed-oxide (MOX) fuel in commercial light-water reactors in the US. This document is intended to describe the revised package design concepts and summarize the results of preliminary analyses and assessments of two new concepts for fresh MOX fuel transport packages that have been developed by Oak Ridge National Laboratory during the past year in support of the Department of Energy/Office of Fissile Materials Disposition

EB Frond wave energy converter - phase 2

Energy Technology Data Exchange (ETDEWEB)

NONE

2005-07-01

The EB Frond project is a wave energy programme developed by The Engineering Business (EB) from an original idea at Lancaster University. The EB Frond is a wave generator with a collector vane on top of an arm that pivots near the seabed. Phase 1 of the project demonstrated the technical feasibility of the project and provided proof of concept. Phase 2 involved further assesment of the technical and commercial viability of the concept through the development of mathematical and physical modelling methods. The work involved small-scale (1/25th) testing in wave tanks at Newcastle and Lancaster Universities and the development, verification and validation of a time domain mathematical model. The decision by EB to put on hold its renewable generation programme meant that plans to test at an intermediate scale (1/16th), assess different survival strategies in extreme wave conditions, carry out site characterisation for full-scale systems and to produce a robust economic model were not fulfilled. However, the mathematical and physical modelling work was used to develop an economic model for the Frond system. This produced a predicted unit cost of electricity by a pre-commercial 5 MW demonstration farm of about 17 pence/kWh. The report discusses the small-scale testing, test results, mathematical modelling, analysis and interpretation, survivability, the economic model and the development route to full-scale production.

The French methodology for EBS confirmation and demonstration

International Nuclear Information System (INIS)

Plas, F.; Voinis, S.; Mayer, S.

2007-01-01

The December 30, 1991 French Waste Act entrusted ANDRA, the French national agency for radioactive waste management, with the task of assessing the feasibility of deep geological disposal of high- and medium-level long-lived waste (HLW and ILW, respectively C-waste and B-waste types in French) plus spent fuel (CU in French). In that context, the 'Dossier 2005 Argile' submitted by ANDRA presents the feasibility assessment - with regard to the technical capacity to accommodate all wastes, to reversibility, and to safety - of a radioactive waste disposal in a clay formation studied at the Meuse/Haute-Marne URL. This report was built upon an iterative approach between site characterisation, design, modelling, phenomenological analysis and safety analysis, in which two principles always guided the elaboration of the safety case: the principle of robustness - repository components must maintain their functionality given reasonable solicitations, taking into account uncertainties on the nature and level of these solicitations; and the principle of demonstrability - safety must be verified without requiring complex demonstrations, and based on multiple lines of evidence/argument (numerical simulation, qualitative arguments such as use of natural analogues, experiments and technological demonstrators). In that respect, the EBS definition, demonstration and confirmation of design is a part of the overall safety case. The 'Dossier 2005 Argile' was submitted to three independent peer reviews. The aim. of this article is to present the methodology that ANDRA implemented in the context of 'Dossier 2005 Argile' for defining, demonstrating and confirming the EBS design as well as the future programme with respect with the new Act of 28 June 2006. (author)

Current state of low energy EB devices and its application technology

International Nuclear Information System (INIS)

Kinoshita, Shinobu

2000-01-01

This paper introduced the current state of low energy type EB (electron beam) devices with an acceleration voltage of 300 kV or below and specific application examples. As for EB devices, it introduced the ultra-compact new EB device (microbeam LV), experimental devices, and the pilot/production devices which have been recently developed by the manufacturer to which the author belongs. As the applications of low energy EB devices, it specifically introduced curing, graft polymerization, crosslinking, and sterilization/disinfection with soft electrons: (1) examples of EB curing; antistatic agents in antibacterial/antifungal property imparting processing, hard coat, printing and topcoat, high gloss/pattern transfer processing, and metal vapor deposition film, (2) example of graft polymerization; barrier imparting films, and (3) examples of crosslinking; shrinking films/tubes and foamed sheets. (A.O.)

UV/EB curing market in Indonesia

International Nuclear Information System (INIS)

Hilmy, N.; Danu, S.

1999-01-01

The most application of UV curing of surface coating in Indonesia are on fancy plywood, furniture and wood flooring industry. Other application are on papers, printing ink/labelling, printed circuit board/PCB and dental materials. At present, application of EB curing coating is still in a pilot plant scale due to the high cost of production. Limited number of application of EB curing by using low energy electron beam machine are on wood panels, ceramics and marbles. This paper describes the market and the problem faced by the largest user of radiation curing systems such as the secondary process plywood, furniture and paper industries

EB curable wetting resins for magnetic media coatings

International Nuclear Information System (INIS)

Laskin, L.; Ansel, R.E.; Murray, K.P.; Schmid, S.R.

1984-01-01

The magnetic media industry is studying means to improve the recording density, durability, product uniformity and production efficiency and to reduce wetting agent migration in the magnetic film. The use of electron beam curable resin binders for magnetic coatings is one of the approaches being studied for this. This paper compares the wetting efficiencies of several electron beam curable systems with a conventional resin and a conventional wetting agent. In this study it has been demonstrated that EB resins can be designed to effect proper magnetic pigment dispersion

EBS modelling for the development of repository concepts tailored to siting environments

International Nuclear Information System (INIS)

Ishiguro, K.; Ueda, H.; Wakasugi, K.; Sakabe, Y.; Kitayama, K.; Umeki, H.; Takase, H.

2007-01-01

The Japanese siting approach for a HLW repository calls for volunteer host municipalities and thereby places particular emphasis on design flexibility. In particular, the repository concept needs to be tailored to the specific site characteristics. Starting from the H12 repository concept, NUMO has been examining a range of possible repository design options, including the EBS. In this paper. the requirements and strategy for the development of models for performance assessment and process understanding are discussed, taking into account the step-wise, iterative process of developing repository concepts. The areas requiring further development of models and databases in the long-term R and D programme have been identified as a 'wish list' that relates to the evaluation of a range of potential repository concepts, focusing on the near-field for the early stages of the development process. Among the issues on the list, NUMO has started the development of a flexible computer code for modelling three-dimensional mass transport to evaluate the impacts of various design options and components of the EBS. This tool has been applied to the analysis of the barrier effects of the tunnel plugs located in fractured rock. (authors)

Material design of negative-tone polyphenol resist for EUV and EB lithography

Science.gov (United States)

Kojima, Kyoko; Mori, Shigeki; Shiono, Daiju; Hada, Hideo; Onodera, Junichi

2007-03-01

In order to enable design of a negative-tone polyphenol resist using polarity-change reaction, five resist compounds (3M6C-MBSA-BLs) with different number of functional group of γ-hydroxycarboxyl acid were prepared and evaluated by EB lithography. The resist using mono-protected compound (3M6C-MBSA-BL1a) showed 40-nm hp resolution at an improved dose of 52 μC/cm2 probably due to removal of a non-protected polyphenol while the sensitivity of the resist using a compound of protected ratio of 1.1 on average with distribution of different protected ratio was 72 μC/cm2. For evaluation of the di-protected compound based resist, a di-protected polyphenol was synthesized by a newly developed synthetic route of 3-steps reaction, which is well-suited for mass production. The resist using di-protected compound (3M6C-MBSA-BL2b) also showed 40-nm hp resolution at a dose of 40 μC/cm2, which was faster than that of mono-protected resist. Fundamental EUV lithographic evaluation of the resist using 3M6C-MBSA-BL2b by an EUV open frame exposure tool (EUVES-7000) gave its estimated optimum sensitivity of 7 mJ/cm2 and a proof of fine development behavior without any swelling.

Evaluation of the PetrifilmTM EB and TEMPO® EB systems with ISO 21528-2:2004 method for the count of Enterobacteriaceae in milk

Directory of Open Access Journals (Sweden)

Andréia Cirolini

2013-09-01

Full Text Available The development of alternative microbiological techniques is driven by the necessity to meet the current needs to deliver rapid results in the manufacturing process of foods, but it is important that these methods be evaluated for each application. The objective of the present study was to assess the PetrifilmTM EB and the TEMPO® EB systems with ISO 21528-2:2004 for the count of Enterobacteriaceae in pasteurized and UHT milk samples. We analyzed the microflora of 141 pasteurized milk samples, 15 samples of artificially contaminated pasteurized milk and 15 samples of artificially contaminated UHT milk. Investigation of the method PetrifilmTM EB and ISO 21528:2 regression analysis showed a high correlation in the samples, r = 0.90 for the microflora of pasteurized milk, r = 0.98 for artificially contaminated pasteurized milk and r = 0.99 for the artificially contaminated UHT milk. In evaluating the system TEMPO EB ® method and ISO 21528:2 correlation was also significant in the analyzed samples, with r = 0.86 for the microflora of pasteurized milk, r = 0.96 for artificially contaminated pasteurized milk and r = 0.99 for artificially contaminated UHT milk. No statistically significant differences were observed between the three methods conducted to analyze artificially contaminated pasteurized and UHT milk at three inoculum levels. In conclusion, the PetrifilmTM EB system and the TEMPO® EB system may be an alternative to the ISO 21528-2:2004 for the Enterobacteriaceae assay for milk as because of the ease-of-operation and the time reduction achieved for conducting the microbiological assay using these systems.

EB detoxification of liquid hazardous wastes

International Nuclear Information System (INIS)

Tata, A.; Giuliani, S.

1996-07-01

In the work, an engineering approach to technical solutions, considering accelerated electron beams as radiation source, is carried out, in order to allow and evaluate an effective recovery of drinking water from highly chemically polluted groundwaters. In connection with different engineering technical and economic parameters (suitable doses, EB-machine type, plant features, etc.) and with reference to 1-100 ton/hr contaminated stream flowrate range (2-50 kGy as considered absorbed dose range), a specifically developed computer code was run. Analysis results, based on investment and functioning cost figures evaluated with reference to industrial plant management scenarios, are treatment unit costs showing a noticeable economic attractiveness of radiation EB-technologies in the field of considered applications

Evaluation of parameters associated with UV/EB cured clearcoats degradation used in outdoor environment

International Nuclear Information System (INIS)

Ruiz, Carmen Silvia Bentivoglio

2003-01-01

The materials curable by ultraviolet (UV) or electron beam (EB) radiation such as inks, adhesives and coatings are reactive compounds made up of resin, monomer, photoinitiator and additives which undergo polymerization and crosslinking under irradiation producing thermoset products. This technology has been used in a great variety of industrial applications, replacing the conventional curing process in the development of new products. One of the challenging applications has been to design weatherable radiation cured coating which maintain their desirable physical properties and aesthetic appearance. This research reports information about the behavior of four UV and EB curable clear coatings -with or without light stabilizer additives- under accelerated weathering. Thermogravimetry, differential scanning calorimetry, differential photo calorimetry, infrared and ultraviolet spectroscopy and tensile properties were used to evaluate these formulations. Clear coating 50 mum thick films were cured with UV and EB radiation at different doses. The UV curing process was carried out at room temperature using an UV tunnel, with a medium pressure mercury lamp and a transport belt with variable speed. The ultraviolet radiation doses were in the range of 50 to 1500 mJ cm -2 . The EB curing process was performed under N 2 atmosphere, with doses in the range from 1,6 to 300 kGy using the IPEN-CNEN/SP Dynamitron electron beam accelerator with energy of 1.5 MeV. The cure degree was determined by means of the residual reaction heat of the under cured samples obtained from photo-DSC or DSC measurements. The accelerated aging tests were carried out using a Weather-Ometer chamber with exposition times in the range of 100 to 3000 hours. The experimental data obtained from the photo-aged samples were evaluated and correlated to the formulation composition, type of radiation - UV or EB, radiation dose and residence time in the aging chamber. The results have shown that the EB cured films

Disposal systems evaluations and tool development : Engineered Barrier System (EBS) evaluation.

Energy Technology Data Exchange (ETDEWEB)

Rutqvist, Jonny (LBNL); Liu, Hui-Hai (LBNL); Steefel, Carl I. (LBNL); Serrano de Caro, M. A. (LLNL); Caporuscio, Florie Andre (LANL); Birkholzer, Jens T. (LBNL); Blink, James A. (LLNL); Sutton, Mark A. (LLNL); Xu, Hongwu (LANL); Buscheck, Thomas A. (LLNL); Levy, Schon S. (LANL); Tsang, Chin-Fu (LBNL); Sonnenthal, Eric (LBNL); Halsey, William G. (LLNL); Jove-Colon, Carlos F.; Wolery, Thomas J. (LLNL)

2011-01-01

Key components of the nuclear fuel cycle are short-term storage and long-term disposal of nuclear waste. The latter encompasses the immobilization of used nuclear fuel (UNF) and radioactive waste streams generated by various phases of the nuclear fuel cycle, and the safe and permanent disposition of these waste forms in geological repository environments. The engineered barrier system (EBS) plays a very important role in the long-term isolation of nuclear waste in geological repository environments. EBS concepts and their interactions with the natural barrier are inherently important to the long-term performance assessment of the safety case where nuclear waste disposition needs to be evaluated for time periods of up to one million years. Making the safety case needed in the decision-making process for the recommendation and the eventual embracement of a disposal system concept requires a multi-faceted integration of knowledge and evidence-gathering to demonstrate the required confidence level in a deep geological disposal site and to evaluate long-term repository performance. The focus of this report is the following: (1) Evaluation of EBS in long-term disposal systems in deep geologic environments with emphasis on the multi-barrier concept; (2) Evaluation of key parameters in the characterization of EBS performance; (3) Identification of key knowledge gaps and uncertainties; and (4) Evaluation of tools and modeling approaches for EBS processes and performance. The above topics will be evaluated through the analysis of the following: (1) Overview of EBS concepts for various NW disposal systems; (2) Natural and man-made analogs, room chemistry, hydrochemistry of deep subsurface environments, and EBS material stability in near-field environments; (3) Reactive Transport and Coupled Thermal-Hydrological-Mechanical-Chemical (THMC) processes in EBS; and (4) Thermal analysis toolkit, metallic barrier degradation mode survey, and development of a Disposal Systems

Disposal systems evaluations and tool development: Engineered Barrier System (EBS) evaluation

International Nuclear Information System (INIS)

Rutqvist, Jonny; Liu, Hui-Hai; Steefel, Carl I.; Serrano de Caro, M.A.; Caporuscio, Florie Andre; Birkholzer, Jens T.; Blink, James A.; Sutton, Mark A.; Xu, Hongwu; Buscheck, Thomas A.; Levy, Schon S.; Tsang, Chin-Fu; Sonnenthal, Eric; Halsey, William G.; Jove-Colon, Carlos F.; Wolery, Thomas J.

2011-01-01

Key components of the nuclear fuel cycle are short-term storage and long-term disposal of nuclear waste. The latter encompasses the immobilization of used nuclear fuel (UNF) and radioactive waste streams generated by various phases of the nuclear fuel cycle, and the safe and permanent disposition of these waste forms in geological repository environments. The engineered barrier system (EBS) plays a very important role in the long-term isolation of nuclear waste in geological repository environments. EBS concepts and their interactions with the natural barrier are inherently important to the long-term performance assessment of the safety case where nuclear waste disposition needs to be evaluated for time periods of up to one million years. Making the safety case needed in the decision-making process for the recommendation and the eventual embracement of a disposal system concept requires a multi-faceted integration of knowledge and evidence-gathering to demonstrate the required confidence level in a deep geological disposal site and to evaluate long-term repository performance. The focus of this report is the following: (1) Evaluation of EBS in long-term disposal systems in deep geologic environments with emphasis on the multi-barrier concept; (2) Evaluation of key parameters in the characterization of EBS performance; (3) Identification of key knowledge gaps and uncertainties; and (4) Evaluation of tools and modeling approaches for EBS processes and performance. The above topics will be evaluated through the analysis of the following: (1) Overview of EBS concepts for various NW disposal systems; (2) Natural and man-made analogs, room chemistry, hydrochemistry of deep subsurface environments, and EBS material stability in near-field environments; (3) Reactive Transport and Coupled Thermal-Hydrological-Mechanical-Chemical (THMC) processes in EBS; and (4) Thermal analysis toolkit, metallic barrier degradation mode survey, and development of a Disposal Systems

RPC industries - UV and EB equipment manufacturers

International Nuclear Information System (INIS)

Rodrigues, A.M.

1987-01-01

RPC Industries has been manufacturing electron beam and ultraviolet equipment for the industrial processing of materials for more than 15 years. RPC maintains its headquarters and electron processor manufacturing plant in Hayward, California. UV equipment is made in the company's plant near Chicago. Sales offices are maintained in New York, Illinois, and California in the USA, and in Germany, Japan, Australia, Italy, Israel, and Sweden. Complete testing and pilot facilities are available in Hayward (EB) and near Chicago (UV). Described below are the basic system components, applications and advantages of RPC's UV and EB systems. (orig.)

Application of calorimeters for 5 MeV EB and bremsstrahlung dosimetry

DEFF Research Database (Denmark)

Sato, T.; Takahashi, T.; Saito, T.

1993-01-01

Graphite and water calorimeters, which were developed for use a 10 MeV electron beams (EB) at Riso National Laboratory, were used for process validation and routine dosimeter calibration at a 5 MeV EB. Water calorimeters were used for reference measurements for 5 MeV EB, the response was found...... to be directly proportional to the beam current and the variation among three water calorimeters was less than +/- 2 % in the range of 10 to 40 kGy. CTA, PMMA, RCD dosimeters were calibrated by irradiating the dosimeters and water calorimeters Simultaneously. The water calorimeter was proved to be an useful tool...... at 5 MeV EB. Graphite calorimeters gave reproducible readings within 3.3 % relative errors (95 % confidence level) for X-ray measurement....

Application of calorimeters for 5 MeV EB and bremsstrahlung dosimetry

International Nuclear Information System (INIS)

Sato, Toshio; Takahashi, Toru; Saito, Toshio; Takehisa, Masaaki; Miller, A.

1993-01-01

Graphite and water calorimeters, which were developed for use with 10 MeV electron beams (EB) at Riso National Laboratory, were used for process validation and routine dosimeter calibration at a 5 MeV EB. Water calorimeters were used for reference measurements for 5 MeV EB, the response was found to be directly proportional to the beam current and the variation among three water calorimeters was less than ± 2% in the range of 10 to 40 kGy. CTA PMMA RCD dosimeters were calibrated by irradiating the dosimeters and water calorimeters simultaneously. The water calorimeter was proved to be an useful tool at 5 MeV EB. Graphite calorimeters gave reproducible readings within 3.3 % relative errors (95% confidence level) for X-ray measurement. (Author)

The Integration and Abstracyion of EBS Models in Yucca Mountain Performance Assessment

Energy Technology Data Exchange (ETDEWEB)

S.D. Sevougian; V. Jain; A.V. Luik

2006-01-11

The safety strategy for geological disposal of radioactive waste at Yucca Mountain relies on a multi-barrier system to contain the waste and isolate it from the biosphere. The multi-barrier system consists of the natural barrier provided by the geological setting and the engineered barrier system (EBS). In the case of Yucca Mountain (YM) the geologic setting is the unsaturated-zone host rock, consisting of about 600 meters of layered ash-flow volcanic tuffs above the water table, and the saturated zone beneath the water table. Both the unsaturated and saturated rocks are part of a closed hydrologic basin in a desert surface environment. The waste is to be buried about halfway between the desert surface and the water table. The primary engineered barriers at YM consist of metal components that are highly durable in an oxidizing environment. The two primary components of the engineered barrier system are highly corrosion-resistant metal waste packages, made from a nickel-chromium-molybdenum alloy, Alloy 22, and titanium drip shields that protect the waste packages from corrosive dripping water and falling rocks. Design and performance assessment of the EBS requires models that describe how the EBS and near field behave under anticipated repository-relevant conditions. These models must describe coupled hydrologic, thermal, chemical, and mechanical (THCM) processes that drive radionuclide transport in a highly fractured host rock, consisting of a relatively permeable network of conductive fractures in a setting of highly impermeable tuff rock matrix. An integrated performance assessment of the EBS must include a quantification of the uncertainties that arise from (1) incomplete understanding of processes and (2) from lack of data representative of the large spatial scales and long time scales relevant to radioactive waste disposal (e.g., long-term metal corrosion rates and heterogeneities in rock properties over the large 5 km{sup 2} emplacement area of the repository

The Integration and Abstraction of EBS Models in Yucca Mountain Performance Assessment

International Nuclear Information System (INIS)

S.D. Sevougian; V. Jain; A.V. Luik

2006-01-01

The safety strategy for geological disposal of radioactive waste at Yucca Mountain relies on a multi-barrier system to contain the waste and isolate it from the biosphere. The multi-barrier system consists of the natural barrier provided by the geological setting and the engineered barrier system (EBS). In the case of Yucca Mountain (YM) the geologic setting is the unsaturated-zone host rock, consisting of about 600 meters of layered ash-flow volcanic tuffs above the water table, and the saturated zone beneath the water table. Both the unsaturated and saturated rocks are part of a closed hydrologic basin in a desert surface environment. The waste is to be buried about halfway between the desert surface and the water table. The primary engineered barriers at YM consist of metal components that are highly durable in an oxidizing environment. The two primary components of the engineered barrier system are highly corrosion-resistant metal waste packages, made from a nickel-chromium-molybdenum alloy, Alloy 22, and titanium drip shields that protect the waste packages from corrosive dripping water and falling rocks. Design and performance assessment of the EBS requires models that describe how the EBS and near field behave under anticipated repository-relevant conditions. These models must describe coupled hydrologic, thermal, chemical, and mechanical (THCM) processes that drive radionuclide transport in a highly fractured host rock, consisting of a relatively permeable network of conductive fractures in a setting of highly impermeable tuff rock matrix. An integrated performance assessment of the EBS must include a quantification of the uncertainties that arise from (1) incomplete understanding of processes and (2) from lack of data representative of the large spatial scales and long time scales relevant to radioactive waste disposal (e.g., long-term metal corrosion rates and heterogeneities in rock properties over the large 5 km 2 emplacement area of the repository). A

Seismic isolation design guidelines for KALIMER(Revision A)

International Nuclear Information System (INIS)

Yoo, B; Koo, Gyeong Hoi; Lee, J. H.

2000-04-01

The main purpose of this report is to develop the seismic isolation design guideline for KALIMER(Korea Advanced LIquid MEtal Reactor). The proposed design rules(revision A) are only applicable to the seismic isolation design with using the high damping laminated rubber bearings. When using other seismic isolation devices and applying to 3-dimensional isolation, the proposed guidelines shall be modified and added with proper research data. The rules described in this report are based on the research results performed up to now but needed to be upgraded and verified with more detail research works for the future

Revised guideline for the approval procedure of package designs in Germany

International Nuclear Information System (INIS)

Nitsche, F.; Roedel, R.

2004-01-01

The IAEA Regulations for the Safe Transport of Radioactive Material, TS-R-1 are applied in Germany through the implementation of the Dangerous Goods Transport Regulations for class 7 of the International Modal Organisations (ADR, RID, IMDG-Code, ICAO-TI). Based on this the approval procedures for packages designs applied in Germany are in compliance with the provisions of TS-R-1. The Guideline R 003 issued by the Ministry of Transport, Building and Housing (BMVBW) in 1991 is the basis for the package design approval procedures in Germany. This Guideline has been reviewed and revised to reflect latest developments in the regulations as well as in the regulatory practice. In particular it has been extended to the approval procedures of Type C packages, packages subject to transitional arrangements, special form and low dispersible radioactive material and provides more detailed information to the applicant about the requested documentation. Publication of this revised guideline has been delayed but it is expected to take place in October 2004. The paper gives an overview about the main parts and provisions of this revised Guideline R 003 with the focus on package design approval procedures

Technical Work Plan for: Near Field Environment: Engineered System: Radionuclide Transport Abstraction Model Report

Energy Technology Data Exchange (ETDEWEB)

J.D. Schreiber

2006-12-08

This technical work plan (TWP) describes work activities to be performed by the Near-Field Environment Team. The objective of the work scope covered by this TWP is to generate Revision 03 of EBS Radionuclide Transport Abstraction, referred to herein as the radionuclide transport abstraction (RTA) report. The RTA report is being revised primarily to address condition reports (CRs), to address issues identified by the Independent Validation Review Team (IVRT), to address the potential impact of transport, aging, and disposal (TAD) canister design on transport models, and to ensure integration with other models that are closely associated with the RTA report and being developed or revised in other analysis/model reports in response to IVRT comments. The RTA report will be developed in accordance with the most current version of LP-SIII.10Q-BSC and will reflect current administrative procedures (LP-3.15Q-BSC, ''Managing Technical Product Inputs''; LP-SIII.2Q-BSC, ''Qualification of Unqualified Data''; etc.), and will develop related Document Input Reference System (DIRS) reports and data qualifications as applicable in accordance with prevailing procedures. The RTA report consists of three models: the engineered barrier system (EBS) flow model, the EBS transport model, and the EBS-unsaturated zone (UZ) interface model. The flux-splitting submodel in the EBS flow model will change, so the EBS flow model will be validated again. The EBS transport model and validation of the model will be substantially revised in Revision 03 of the RTA report, which is the main subject of this TWP. The EBS-UZ interface model may be changed in Revision 03 of the RTA report due to changes in the conceptualization of the UZ transport abstraction model (a particle tracker transport model based on the discrete fracture transfer function will be used instead of the dual-continuum transport model previously used). Validation of the EBS-UZ interface model

Technical Work Plan for: Near Field Environment: Engineered Barrier System: Radionuclide Transport Abstraction Model Report

International Nuclear Information System (INIS)

J.D. Schreiber

2006-01-01

This technical work plan (TWP) describes work activities to be performed by the Near-Field Environment Team. The objective of the work scope covered by this TWP is to generate Revision 03 of EBS Radionuclide Transport Abstraction, referred to herein as the radionuclide transport abstraction (RTA) report. The RTA report is being revised primarily to address condition reports (CRs), to address issues identified by the Independent Validation Review Team (IVRT), to address the potential impact of transport, aging, and disposal (TAD) canister design on transport models, and to ensure integration with other models that are closely associated with the RTA report and being developed or revised in other analysis/model reports in response to IVRT comments. The RTA report will be developed in accordance with the most current version of LP-SIII.10Q-BSC and will reflect current administrative procedures (LP-3.15Q-BSC, ''Managing Technical Product Inputs''; LP-SIII.2Q-BSC, ''Qualification of Unqualified Data''; etc.), and will develop related Document Input Reference System (DIRS) reports and data qualifications as applicable in accordance with prevailing procedures. The RTA report consists of three models: the engineered barrier system (EBS) flow model, the EBS transport model, and the EBS-unsaturated zone (UZ) interface model. The flux-splitting submodel in the EBS flow model will change, so the EBS flow model will be validated again. The EBS transport model and validation of the model will be substantially revised in Revision 03 of the RTA report, which is the main subject of this TWP. The EBS-UZ interface model may be changed in Revision 03 of the RTA report due to changes in the conceptualization of the UZ transport abstraction model (a particle tracker transport model based on the discrete fracture transfer function will be used instead of the dual-continuum transport model previously used). Validation of the EBS-UZ interface model will be revised to be consistent with

EB treatment of carbon nanotube-reinforced polymer composites

International Nuclear Information System (INIS)

Szebenyi, G.; Romhany, G.; Czvikovszky, T.; Vajna, B.

2011-01-01

Complete text of publication follows. A small amount - less than 0.5% - carbon nanotube reinforcement may improve significantly the mechanical properties of epoxy based composite materials. The basic technical problem is on one side the dispersion of the nanotubes into the viscous matrix resin. Namely the fine, powder-like - less than 100 nanometer diameter - nanotubes are prone to form aggregates. On the other side, the good connection between the nanofiber and matrix, - which is determining the success of the reinforcement, - requires some efficient adhesion promoting treatment. After an elaborate masterbatch mixing technology we applied Electron Beam treatment of epoxy-matrix polymer composites containing carbon nanotubes in presence of vinylester resins. The Raman spectra of vinylester-epoxy mixtures treated by an 8 MeV EB showed the advantage of the electron treatment. Even in the case of partially immiscible epoxy and vinylester resins, the anchorage of carbon nanotubes reflects improvement if a reasonable 25 kGy EB dose is applied. Atomic Force Microscopy as well as mechanical tests on flexural and impact properties confirm the benefits of EB treatment. Simultaneous application of multiwall carbon nanotubes and 'conventional' carbon fibers as reinforcement in vinylester modified epoxies results in new types of hybrid nanocomposites as engineering materials. The bending- and interlaminar properties of such hybrid systems showed the beneficial effect of the EB treatment. Acknowledgement: This work has been supported by the New Hungary Development Plan (Project ID: TAMOP-4.2.1/B-09/1/KMR-2010-0002).

TIP maker and TIP marker; EB1 as a master controller of microtubule plus ends.

Science.gov (United States)

Vaughan, Kevin T

2005-10-24

The EB1 protein is a member of the exciting and enigmatic family of microtubule (MT) tip-tracking proteins. EB1 acts as an exquisite marker of dynamic MT plus ends in some cases, whereas in others EB1 is thought to directly dictate the behavior of the plus ends. How EB1 differentiates between these two roles remains unclear; however, a growing list of interactions between EB1 and other MT binding proteins suggests there may be a single mechanism. Adding another layer of complexity to these interactions, two studies published in this issue implicate EB1 in cross-talk between mitotic MTs and between MTs and actin filaments (Goshima et al., p. 229; Wu et al., p. 201). These results raise the possibility that EB1 is a central player in MT-based transport, and that the activity of MT-binding proteins depends on their ability or inability to interact with EB1.

Single photon detection and localization accuracy with an ebCMOS camera

Energy Technology Data Exchange (ETDEWEB)

Cajgfinger, T. [CNRS/IN2P3, Institut de Physique Nucléaire de Lyon, Villeurbanne F-69622 (France); Dominjon, A., E-mail: agnes.dominjon@nao.ac.jp [Université de Lyon, Université de Lyon 1, Lyon 69003 France. (France); Barbier, R. [CNRS/IN2P3, Institut de Physique Nucléaire de Lyon, Villeurbanne F-69622 (France); Université de Lyon, Université de Lyon 1, Lyon 69003 France. (France)

2015-07-01

The CMOS sensor technologies evolve very fast and offer today very promising solutions to existing issues facing by imaging camera systems. CMOS sensors are very attractive for fast and sensitive imaging thanks to their low pixel noise (1e-) and their possibility of backside illumination. The ebCMOS group of IPNL has produced a camera system dedicated to Low Light Level detection and based on a 640 kPixels ebCMOS with its acquisition system. After reminding the principle of detection of an ebCMOS and the characteristics of our prototype, we confront our camera to other imaging systems. We compare the identification efficiency and the localization accuracy of a point source by four different photo-detection devices: the scientific CMOS (sCMOS), the Charge Coupled Device (CDD), the Electron Multiplying CCD (emCCD) and the Electron Bombarded CMOS (ebCMOS). Our ebCMOS camera is able to identify a single photon source in less than 10 ms with a localization accuracy better than 1 µm. We report as well efficiency measurement and the false positive identification of the ebCMOS camera by identifying more than hundreds of single photon sources in parallel. About 700 spots are identified with a detection efficiency higher than 90% and a false positive percentage lower than 5. With these measurements, we show that our target tracking algorithm can be implemented in real time at 500 frames per second under a photon flux of the order of 8000 photons per frame. These results demonstrate that the ebCMOS camera concept with its single photon detection and target tracking algorithm is one of the best devices for low light and fast applications such as bioluminescence imaging, quantum dots tracking or adaptive optics.

The chemistry of UV and EB radiation curing

International Nuclear Information System (INIS)

Garnett, J.L.

1987-01-01

The application of photopolymerisation (UV) and electron beam (EB) technologies in radiation rapid cure (RRC) processing is discussed. The chemistry associated with such reactions and the mechanisms of the processes are treated. The occurrence of concurrent grafting to substrate with radiation curing of film is shown to be an advantage in enhancing the properties of certain finished products. The parameters influencing the optimum grafting yield in such RRC processes are discussed. In many applications, the chemistry of the process combined with the machine, expecially for EB, is shown a so-called ''turn-key'' operation. (author)

A Revised Interface for the ARL Topodef Mobility Design Tool

Science.gov (United States)

2012-04-01

designed paths as though moving down a conveyor belt . Giving paths an existence independent of the nodes that travel along them not only makes their...A Revised Interface for the ARL Topodef Mobility Design Tool by Andrew J. Toth and Michael Christensen ARL-TR-5980 April 2012...Disclaimers The findings in this report are not to be construed as an official Department of the Army position unless so designated by other

End-Binding Protein 1 (EB1) Up-regulation is an Early Event in Colorectal Carcinogenesis

Science.gov (United States)

Stypula-Cyrus, Yolanda; Mutyal, Nikhil N.; Cruz, Mart Angelo Dela; Kunte, Dhananjay P.; Radosevich, Andrew J.; Wali, Ramesh; Roy, Hemant K.; Backman, Vadim

2014-01-01

End-binding protein (EB1) is a microtubule protein that binds to the tumor suppressor adenomatous polyposis coli (APC). While EB1 is implicated as a potential oncogene, its role in cancer progression is unknown. Therefore, we analyzed EB1/APC expression at the earliest stages of colorectal carcinogenesis and in the uninvolved mucosa ("field effect") of human and animal tissue. We also performed siRNA-knockdown in colon cancer cell lines. EB1 is up-regulated in early and field carcinogenesis in the colon, and the cellular/nano-architectural effect of EB1 knockdown depended on the genetic context. Thus, dysregulation of EB1 is an important early event in colon carcinogenesis. PMID:24492008

E.B. White: Aspects of Style.

Science.gov (United States)

Neumeyer, Peter F.

1987-01-01

Assesses the writing style of a famous author of children's books, concluding that E.B. White's informal tone uses anaphora, simple sentences, doubling and redundancy, and mixes colloquial with standard English. Provides examples of his style, from 10 years old to maturity. (NKA)

EB and EUV lithography using inedible cellulose-based biomass resist material

Science.gov (United States)

Takei, Satoshi; Hanabata, Makoto; Oshima, Akihiro; Kashiwakura, Miki; Kozawa, Takahiro; Tagawa, Seiichi

2016-03-01

The validity of our approach of inedible cellulose-based resist material derived from woody biomass has been confirmed experimentally for the use of pure water in organic solvent-free water spin-coating and tetramethylammonium hydroxide(TMAH)-free water-developable techniques of eco-conscious electron beam (EB) and extreme-ultraviolet (EUV) lithography. The water developable, non-chemically amplified, high sensitive, and negative tone resist material in EB and EUV lithography was developed for environmental affair, safety, easiness of handling, and health of the working people. The inedible cellulose-based biomass resist material was developed by replacing the hydroxyl groups in the beta-linked disaccharides with EB and EUV sensitive groups. The 50-100 nm line and space width, and little footing profiles of cellulose-based biomass resist material on hardmask and layer were resolved at the doses of 10-30 μC/cm2. The eco-conscious lithography techniques was referred to as green EB and EUV lithography using inedible cellulose-based biomass resist material.

Main studies results for introduction of EB machine to Vietnam and for its application

International Nuclear Information System (INIS)

Tran, Khac An; Nguyen, Quoc Hien; Le, Hai

2004-01-01

Upon the national program on utilization of EB machine for research and development purposes and the FNCA project on application of electron accelerator, as a counterpart the Research and Development Center for Radiation Technology (VINAGAMMA) is preparing technical, manpower and financial conditions for introduction of an EB machine for R and D purposes. The paper offers main studied results in the field of Radiation Processing aimed at putting applications of EB technology into Vietnam and studies on selection of EB machine for R and D purposes in Vietnam. (author)

High-sensitivity green resist material with organic solvent-free spin-coating and tetramethylammonium hydroxide-free water-developable processes for EB and EUV lithography

Science.gov (United States)

Takei, Satoshi; Hanabata, Makoto; Oshima, Akihiro; Kashiwakura, Miki; Kozawa, Takahiro; Tagawa, Seiichi

2015-03-01

We investigated the eco-friendly electron beam (EB) and extreme-ultraviolet (EUV) lithography using a high-sensitive negative type of green resist material derived from biomass to take advantage of organic solvent-free water spin-coating and tetramethylammonium hydroxide(TMAH)-free water-developable techniques. A water developable, non-chemically amplified, high sensitive, and negative tone resist material in EB lithography was developed for environmental affair, safety, easiness of handling, and health of the working people, instead of the common developable process of TMAH. The material design concept to use the water-soluble resist material with acceptable properties such as pillar patterns with less than 100 nm in high EB sensitivity of 10 μC/cm2 and etch selectivity with a silicon-based middle layer in CF4 plasma treatment was demonstrated for EB and EUV lithography.

Evaluations of 1990 PRISM design revisions

International Nuclear Information System (INIS)

Van Tuyle, G.J.; Slovik, G.C.; Chan, B.C.; Aronson, A.L.; Kennett, R.J.

1992-03-01

Analyses of the 1990 version of the PRISM Advanced Liquid Metal Reactor (ALMR) design are presented and discussed. Most of the calculations were performed using BNL computer codes, particularly SSC and MINET. In many cases, independent BNL calculations were compared against analyses presented by General Electric when they submitted the PRISM design revisions for evaluation by the Nuclear Regulatory Commission (NRC). The current PRISM design utilizes the metallic fuel developed by Argonne National Laboratory (ANL) which facilitates the passive/''inherent'' shutdown mechanism that acts to shut down reactor power production whenever the system overheats. There are a few vulnerabilities in the passive shutdown, with the most worrisome being the positive feedback from sodium density decreases or sodium voiding. Various postulated unscrammed events were examined by GE and/or BNL, and much of the analysis discussed in this report is focused on this category of events. For the most part, the BNL evaluations confirm the information submitted by General Electric. The principal areas of concern are related to the performance of the ternary metal fuel, and may be resolved as ANL continues with its fuel development and testing program

THE CONCEPT OF INTEGRATED ENGINEERING AND BUSINESS (EB EDUCATION SYSTEM

Directory of Open Access Journals (Sweden)

Michał Charlak

2013-12-01

Full Text Available In our approach to engineering and business education system an engineer is a man working as creator and user of technical products. We stress that the process of understanding and gaining knowledge of technical reality and creativity of engineers are the essential for EB concept . Next, we describe briefly three perspectives for building the system of innovative product origination as a basis for EB system: 1 designer’s perspective; 2 business perspective. 3 consumer perspective.

Post-irradiation mechanical tests on F82H EB and TIG welds

International Nuclear Information System (INIS)

Rensman, J.; Osch, E.V. van; Horsten, M.G.; D'Hulst, D.S.

2000-01-01

The irradiation behaviour of electron beam (EB) and tungsten inert gas (TIG) welded joints of the reduced-activation martensitic steel IEA heat F82H-mod. was investigated by neutron irradiation experiments in the high flux reactor (HFR) in Petten. Mechanical test specimens, such as tensile specimens and KLST-type Charpy impact specimens, were neutron irradiated up to a dose level of 2-3 dpa at a temperature of 300 deg. C in the HFR reactor in Petten. The tensile results for TIG and EB welds are as expected with practically no strain hardening capacity left. Considering impact properties, there is a large variation in impact properties for the TIG weld. The irradiation tends to shift the DBTT of particularly the EB welds to very high values, some cases even above +250 deg. C. PWHT of EB-welded material gives a significant improvement of the DBTT and USE compared to the as-welded condition

Thermal conductivity issues of EB-PVD thermal barrier coatings

Energy Technology Data Exchange (ETDEWEB)

Schulz, U.; Raetzer-Scheibe, H.J.; Saruhan, B. [DLR - German Aerospace Center, Institute of Materials Research, 51170 Cologne (Germany); Renteria, A.F. [BTU, Physical Metallurgy and Materials Technology, Cottbus (Germany)

2007-09-15

The thermal conductivity of electron-beam physical vapor deposited (EB-PVD) thermal barrier coatings (TBCs) was investigated by the Laser Flash technique. Sample type and methodology of data analyses as well as atmosphere during the measurement have some influence on the data. A large variation of the thermal conductivity was found by changes in TBC microstructure. Exposure at high temperature caused sintering of the porous microstructure that finally increased thermal conductivity up to 30 %. EB-PVD TBCs show a distinct thickness dependence of the thermal conductivity due to the anisotropic microstructure in thickness direction. Thin TBCs had a 20 % lower thermal conductivity than thick coatings. New compositions of the ceramic top layer offer the largest potential to lower thermal conductivity. Values down to 0.8W/(mK) have been already demonstrated with virgin coatings of pyrochlore compositions. (Abstract Copyright [2007], Wiley Periodicals, Inc.) [German] Die Waermeleitfaehigkeit von elektronenstrahl-aufgedampften (EB-PVD) Waermedaemmschichten (TBCs) wurde mittels Laser-Flash untersucht. Probentyp, Messmethodik und die Atmosphaere waehrend der Messung haben einen Einfluss auf die Ergebnisse. Aenderungen in der Mikrostruktur der TBC fuehrten zu grossen Unterschieden der Waermeleitfaehigkeit. Eine Hochtemperaturbelastung verursachte Sintervorgaenge in der poroesen Mikrostruktur, was die Waermeleitfaehigkeit um bis zu 30 % ansteigen liess. EB-PVD TBCs zeigen eine deutliche Dickenabhaengigkeit der Waermeleitfaehigkeit durch die Anisotropie der Mikrostruktur in dieser Richtung. Duenne TBCs haben eine um 20 % geringere Waermeleitfaehigkeit als dicke Schichten. Neue Zusammensetzungen der keramischen Deckschicht bieten die groessten Moeglichkeiten fuer eine Reduktion der Waermeleitfaehigkeit. Werte bis zu 0,8 W/(mK) wurden damit bereits erreicht. (Abstract Copyright [2007], Wiley Periodicals, Inc.)

EB-welding of the copper canister for the nuclear waste disposal. Final report of the development programme 1994-1997

International Nuclear Information System (INIS)

Aalto, H.

1998-10-01

During 1994-1997 Posiva Oy and Outokumpu Poricopper Oy had a joint project Development of EB-welding method for massive copper canister manufacturing. The project was part of the national technology program 'Weld 2000' and it was supported financially by Technology Development Centre (TEKES). The spent fuel from Finnish nuclear reactors is planned to be encapsulated in thick-walled copper canisters and placed deep into the bedrock. The thick copper layer of the canister provides a long time corrosion resistance and prevents deposited nuclear fuel from contact with water. The quality requirements of the copper components are high because of the designed long lifetime of the canister. The EB-welding technology has proved to be applicable method for the production of the copper canisters and the EB-welding technique is needed at least when the lids of the copper canister will be closed. There are a number of parameters in EB-welding which affect weldability. However, the effect of the welding parameters and their optimization has not been extensively studied in welding of thick copper sections using conventional high vacuum EB-welding. One aim of this development work was to extensively study effect of welding parameters on weld quality. The final objective was to minimise welding defects in the main weld and optimize slope out procedure in thick copper EB-welding. Welding of 50 mm thick copper sections was optimized using vertical and horizontal EB-welding techniques. As a result two full scale copper lids were welded to a short cylinder successfully. The resulting weld quality with optimised welding parameters was reasonable good. The optimised welding parameters for horizontal and vertical beam can be applied to the longitudinal body welds of the canister. The optimal slope out procedure for the lid closure needs some additional development work. In addition of extensive EB-welding program ultrasonic inspection and creep strength of the weld were studied. According

EB-welding of the copper canister for the nuclear waste disposal. Final report of the development programme 1994-1997

Energy Technology Data Exchange (ETDEWEB)

Aalto, H. [Outokumpu Oy Poricopper, Pori (Finland)

1998-10-01

During 1994-1997 Posiva Oy and Outokumpu Poricopper Oy had a joint project Development of EB-welding method for massive copper canister manufacturing. The project was part of the national technology program `Weld 2000` and it was supported financially by Technology Development Centre (TEKES). The spent fuel from Finnish nuclear reactors is planned to be encapsulated in thick-walled copper canisters and placed deep into the bedrock. The thick copper layer of the canister provides a long time corrosion resistance and prevents deposited nuclear fuel from contact with water. The quality requirements of the copper components are high because of the designed long lifetime of the canister. The EB-welding technology has proved to be applicable method for the production of the copper canisters and the EB-welding technique is needed at least when the lids of the copper canister will be closed. There are a number of parameters in EB-welding which affect weldability. However, the effect of the welding parameters and their optimization has not been extensively studied in welding of thick copper sections using conventional high vacuum EB-welding. One aim of this development work was to extensively study effect of welding parameters on weld quality. The final objective was to minimise welding defects in the main weld and optimize slope out procedure in thick copper EB-welding. Welding of 50 mm thick copper sections was optimized using vertical and horizontal EB-welding techniques. As a result two full scale copper lids were welded to a short cylinder successfully. The resulting weld quality with optimised welding parameters was reasonable good. The optimised welding parameters for horizontal and vertical beam can be applied to the longitudinal body welds of the canister. The optimal slope out procedure for the lid closure needs some additional development work. In addition of extensive EB-welding program ultrasonic inspection and creep strength of the weld were studied. According

Scania RBS brake system; Das Bremssystem EBS von Scania

Energy Technology Data Exchange (ETDEWEB)

Winterhagen, J.

1996-09-01

Scania claims to be the first producer of industrial vehicles to market an electronic braking system (EBS) combined with disc brakes for all axles. The new braking systems for long-distance trailers were presented for the first time at the IAA, Hanover, in September 1996. (orig.) [Deutsch] Scania ist nach eigenen Angaben der erste Lkw-Hersteller, der eine elektronisch geregelte Bremsanlage (EBS) in Kombination mit Scheibenbremsen an allen Achsen auf den Markt bringt. Der Oeffentlichkeit stellt Scania das neue Bremssystem fuer die Fernverkehrs-Zugmaschinen der Baureihe 4 zum ersten Mal auf der IAA in Hannover im September 1996 vor. (orig.)

E.B. White and Charlotte's Web.

Science.gov (United States)

Elledge, Scott

2001-01-01

Discusses the life and work of E.B. White, describing his research on spiders, examining his development of the story, "Charlotte's Web," and explaining how "Charlotte's Web" is a fabric of memories. Notes how this book faces a variety of truths about the human condition and how it celebrates a child's generous view of and love…

Revision of the design model for a cryogenic falling liquid film helium separator

International Nuclear Information System (INIS)

Kinoshita, Masahiro; Bartlit, J.R.; Sherman, R.H.

1983-05-01

The present paper reports revision of the design model previously developed by the authors for the cryogenic falling liquid film helium separator. The revised design procedure is composed of three steps : 1) calculation of distributions of phase flow rates, temperature and phase compositions within the refrigerated section and the packed section ; 2) calculation of more detailed distributions of these variables within the refrigerated section ; and 3) estimation of column dimensions and determination of operating conditions. It is assumed that the vacant refrigerated section has two theoretical stages for hydrogen isotope separation. The mixture within the refrigerated section is considered in step 2) as two component system of He-HD. (author)

The removal of VOC from air using EB, MW and catalyst - Laboratory plant results

International Nuclear Information System (INIS)

Calinescu, I.; Ighigeanu, D.; Martin, D.

2011-01-01

A new hybrid technique for the VOCs removal from gases, based on the combined use of EB induced NTP (non-thermal plasma), MW induced NTP and catalytic oxidation, named “EB+MW-plasma catalysis”, is presented. The main goal of our research was to combine the features of each known technique used in gas pollution control, i.e. the very high efficiency of EB in converting VOCs to intermediate products, the ability of MW to produce and sustain NTP in large electrodeless reactors, and the important role of catalysts in the complete conversion to CO 2 and H 2 O. Our experiences shown that the two means of treating the gases are complementary: the catalytic oxidation in the presence of MW is efficient for high VOC initial concentrations and low flow rates while the exclusive use of the EB irradiation determines high decomposition efficiencies only in the case of very low concentrations of VOC but for large flow rates. Real synergistic effects between NTP and catalysis were obtained by introducing the catalyst into the irradiation zone. The main conclusion of this work is that the combined treatment EB+MW+catalyst improves both decomposition efficiency and oxidation efficiency. The EB+MW+Catalysis method demonstrated good results on a wide range of concentrations and flow rates. (author)

Investigating the Potential Barrier Function of Nanostructured Materials Formed in Engineered Barrier Systems (EBS) Designed for Nuclear Waste Isolation.

Science.gov (United States)

Cuevas, Jaime; Ruiz, Ana Isabel; Fernández, Raúl

2018-02-21

Clay and cement are known nano-colloids originating from natural processes or traditional materials technology. Currently, they are used together as part of the engineered barrier system (EBS) to isolate high-level nuclear waste (HLW) metallic containers in deep geological repositories (DGR). The EBS should prevent radionuclide (RN) migration into the biosphere until the canisters fail, which is not expected for approximately 10 3  years. The interactions of cementitious materials with bentonite swelling clay have been the scope of our research team at the Autonomous University of Madrid (UAM) with participation in several European Union (EU) projects from 1998 up to now. Here, we describe the mineral and chemical nature and microstructure of the alteration rim generated by the contact between concrete and bentonite. Its ability to buffer the surrounding chemical environment may have potential for further protection against RN migration. © 2018 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

EB dose calibration for 10 MeV linear accelerator

International Nuclear Information System (INIS)

Owczarczyk, H.B.; Migdal, W.; Stachowicz, W.

2002-01-01

The National Institute of Standards and Technology Gaitherburg USA has done in co-operation with INCT Warsaw the EPR dose measurements for two INCT 60 Co irradiators using l-alanine standard pellets as dosimeter medium. In the study the comparative EPR measurements of doses up to 40 kGy have been done using l-alanine powder with 60 Co source (reference to NIST standard) and EB linear accelerator, respectively. On the basis of this comparative study 5% correction factor for EB dose measurements has been adapted in the INCT Experimental Plant for Food Irradiation traceable to the dose estimations done with the Risoe calorimetric system

Modelling Coupled Processes in the Evolution of Repository Engineered Barrier Systems using QPAC-EBS

Energy Technology Data Exchange (ETDEWEB)

Maul, Philip; Benbow, Steven; Bond, Alex; Robinson, Peter (Quintessa Limited, Henley-on-Thames (United Kingdom))

2010-08-15

A satisfactory understanding of the evolution of repository engineered barrier systems (EBS) is an essential part of the safety case for the repository. This involves consideration of coupled Thermal (T), Hydro (H), Mechanical (M) and Chemical (C) processes. Quintessa's general-purpose modelling code QPAC is capable of representing strongly coupled non-linear processes and has been used in a wide range of applications. This code is the basis for software used by Quintessa in studies of the evolution of the EBS in a deep repository for spent nuclear fuel undertaken for SKI and then SSM since 2007. The collection of software components employed has been referred to collectively as QPAC-EBS, consisting of the core QPAC code together with relevant modules for T, H, M and C processes. QPAC-EBS employs a fundamentally different approach from dedicated codes that model such processes (although few codes can represent each type of process), enabling the specification of new processes and the associated governing equations in code input. Studies undertaken to date have demonstrated that QPAC-EBS can be used effectively to investigate both the early evolution of the EBS and important scenarios for the later evolution of the system when buffer erosion and canister corrosion may occur. A key issue for modelling EBS evolution is the satisfactory modelling of the behaviour of the bentonite buffer. Bentonite is a difficult material to model, partly because of the complex coupled mechanical, hydro and chemical processes involved in swelling during resaturation. Models employed to date have generally taken an empirical approach, but a new model developed during the EU THERESA project could be further developed to provide a better representation of these processes. QPAC-EBS could play an important role in supporting SSM.s review of the forthcoming SR-Site assessment by SKB if used by Quintessa in independent supporting calculations. To date radionuclide transport calculations

The removal of VOC from air using EB, MW and catalyst - Laboratory plant results

Energy Technology Data Exchange (ETDEWEB)

Calinescu, I. [Polytechnic University, Bucharest (Romania); Ighigeanu, D.; Martin, D. [National Institute for Lasers, Plasma and Radiation Physics, Bucharest (Romania)

2011-07-01

A new hybrid technique for the VOCs removal from gases, based on the combined use of EB induced NTP (non-thermal plasma), MW induced NTP and catalytic oxidation, named “EB+MW-plasma catalysis”, is presented. The main goal of our research was to combine the features of each known technique used in gas pollution control, i.e. the very high efficiency of EB in converting VOCs to intermediate products, the ability of MW to produce and sustain NTP in large electrodeless reactors, and the important role of catalysts in the complete conversion to CO{sub 2} and H{sub 2}O. Our experiences shown that the two means of treating the gases are complementary: the catalytic oxidation in the presence of MW is efficient for high VOC initial concentrations and low flow rates while the exclusive use of the EB irradiation determines high decomposition efficiencies only in the case of very low concentrations of VOC but for large flow rates. Real synergistic effects between NTP and catalysis were obtained by introducing the catalyst into the irradiation zone. The main conclusion of this work is that the combined treatment EB+MW+catalyst improves both decomposition efficiency and oxidation efficiency. The EB+MW+Catalysis method demonstrated good results on a wide range of concentrations and flow rates. (author)

Adhesion and interface problems of EB-PVD thermal barrier coatings; Grenzschichtproblematik und Haftung von EB-PVD-Waermedaemmschichtsystemen

Energy Technology Data Exchange (ETDEWEB)

Fritscher, K.; Leyens, C. [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Koeln (Germany). Inst. fuer Werkstoff-Forschung

1996-12-31

Loss of adhesion in thermal insulation layers produced by EB-PVD may be caused by surface morphologies or oxide phases resulting from previous process stages, e.g. shot peening, or inappropriate annealing conditions. These undesirable oxide phases are mostly spinels and silicates which pose mechanical problems. Annealing and densification must be modified in order to promote the formation of {alpha}-Al{sub 2}O{sub 3} layers. It may also be possible to avoid certain categories of flaws by changing one material partner (e.g. by using {beta}-NiAl-free adhesive layers). [Deutsch] Die Ursachen der Einbussen der Haftung in WDS-Systemen aus EB-PVD-Fertigung liegen oft in der Ausbildung von Oberflaechenmorphologien oder von Oxidphasen begruendet, die aus den der WDS-Beschichtung vorangehenden Verfahrensschritten wie z.B. des Glasperlstrahlens und von unangemessenen Gluehbedingungen herruehren koennen. Bei diesen unerwuenschten Oxidphasen handelt es sich u.a. um Spinelle und Silikate, die in mechanischer Hinsicht problematisch sind. Glueh- und Verdichtungsroutinen sind entsprechend zu modifizieren, um die Bildung von {alpha}-Al{sub 2}O{sub 3}-Schichten zu foerdern. Moeglicherweise sind gewisse Fehlerkategorien bereits dadurch zu umgehen, dass ein Materialpartner geaendert wird (Beispiel: {beta}-NiAl-freie Haftschichten anwenden). (orig.)

Thermocyclic behaviour of microstructurally modified EB-PVD thermal barrier coatings

International Nuclear Information System (INIS)

Schulz, U.; Fritscher, K.; Raetzer-Scheibe, H.-J.; Kaysser, W.A.; Peters, M.

1997-01-01

This paper focuses on the combined effects of substrate temperature and rotation during electron-beam physical vapor deposition (EB-PVD) on the columnar microstructure of yttria partially stabilized zirconia (YPSZ) thermal barrier coatings. Diameter and degree of ordering of the columns and the density of the coatings are sensitive to the processing parameters. Results are discussed in the frame of common structural zone models for PVD processes. The models are extended to consider the rotational effect. EB-PVD YPSZ TBCs of different column diameters were deposited on top of an EB-PVD NiCoCrAlY bondcoat on IN 100 superalloy test bars. The performance of the TBCs was investigated in a cyclic oxidation furnace test rig between 1100 C and 130 C and in a burner rig under hot gas corrosion conditions at a maximum temperature of 900 C. Results showed a correlation between cyclic lifetime and the various microstructures of the TBCs. Samples having a non-regular arrangement of columns performed best in both tests. (orig.)

The EB factory project. II. Validation with the Kepler field in preparation for K2 and TESS

Energy Technology Data Exchange (ETDEWEB)

Parvizi, Mahmoud; Paegert, Martin; Stassun, Keivan G., E-mail: mahmoud.parvizi@vanderbilt.edu [Department of Physics and Astronomy, Vanderbilt University, VU Station B 1807, Nashville, TN 37235 (United States)

2014-12-01

Large repositories of high precision light curve data, such as the Kepler data set, provide the opportunity to identify astrophysically important eclipsing binary (EB) systems in large quantities. However, the rate of classical “by eye” human analysis restricts complete and efficient mining of EBs from these data using classical techniques. To prepare for mining EBs from the upcoming K2 mission as well as other current missions, we developed an automated end-to-end computational pipeline—the Eclipsing Binary Factory (EBF)—that automatically identifies EBs and classifies them into morphological types. The EBF has been previously tested on ground-based light curves. To assess the performance of the EBF in the context of space-based data, we apply the EBF to the full set of light curves in the Kepler “Q3” Data Release. We compare the EBs identified from this automated approach against the human generated Kepler EB Catalog of ∼2600 EBs. When we require EB classification with ⩾90% confidence, we find that the EBF correctly identifies and classifies eclipsing contact (EC), eclipsing semi-detached (ESD), and eclipsing detached (ED) systems with a false positive rate of only 4%, 4%, and 8%, while complete to 64%, 46%, and 32%, respectively. When classification confidence is relaxed, the EBF identifies and classifies ECs, ESDs, and EDs with a slightly higher false positive rate of 6%, 16%, and 8%, while much more complete to 86%, 74%, and 62%, respectively. Through our processing of the entire Kepler “Q3” data set, we also identify 68 new candidate EBs that may have been missed by the human generated Kepler EB Catalog. We discuss the EBF's potential application to light curve classification for periodic variable stars more generally for current and upcoming surveys like K2 and the Transiting Exoplanet Survey Satellite.

Residual stress investigation of copper plate and canister EB-Welds Complementary Results

International Nuclear Information System (INIS)

Gripenberg, H.

2009-03-01

The residual stresses in copper as induced by EB-welding were studied by specimens where the weld had two configurations: either a linear or a circumferential weld. This report contains the residual stress measurements of two plates, containing linear welds, and the full-scale copper lid specimen to which a hollow cylinder section had been joined by a circumferential EB-weld. The residual stress state of the EB-welded copper specimens was investigated by X-ray diffraction (XRD), hole drilling (HD) ring core (RC) and contour method (CM). Three specimens, canister XK010 and plates X251 and X252, were subjected to a thorough study aiming at quantitative determination of the residual stress state in and around the EB-welds using XRD for surface and HD and RC for spatial stress analysis. The CM maps one stress component over a whole cross section. The surface residual stresses measured by XRD represent the machined condition of the copper material. The XRD study showed that the stress changes towards compression close to the weld in the hollow cylinder, which indicates shrinkage in the hoop direction. According to the same analogy, the shrinkage in the axial direction is much smaller. The HD measurements showed that the stress state in the base material is bi-axial and, in terms of von Mises stress, 50 MPa for the plates and 20 MPa for the cylinder part of the canister. The stress state in the EB-welds of all specimens differs clearly from the stress state in the base material being more tensile, with higher magnitudes of von Mises stress in the plate than in the canister welds. The HD and RC results were obtained using linear elastic theory. The RC measurements showed that the maximum principal stress in the BM is close to zero near the surface and it becomes slightly tensile, 10 MPa, deeper under the surface. Welding pushed the general stress state towards tension with the maximum principal stress reaching 50 MPa, deeper than 5 mm below the surface in the weld. The

[A case with chronic active EB virus infection accompanied with pulmonary candidiasis].

Science.gov (United States)

Karino, T; Nakamura, J; Fujita, K; Kobashi, Y; Yano, T; Okimoto, N; Soejima, R

1998-12-01

A 44-year-old woman with a history of intermittent fever for several years was admitted because of burn on her leg. On admission, she had hepatosplenomegaly and fever. Antibiotic therapy was started for bacterial infection of the burn. She lost her appetite and IVH was started. During the treatment, high fever appeared and chest X-ray films showed multiple nodular infiltrates throughout both lung fields. Candida albicans was isolated from IVH catheter culture and pulmonary candidiasis was suspected. Her fever and lung involvements were successfully treated with fluconazole. During the course, serum anti-EB-VCA-IgG antibody persisted at a high titer and anti-EBNA antibody remained negative. EB virus DNA was detected in the peripheral blood and bone marrow. Thus, she was diagnosed as chronic active EB virus infection.

Towards energy efficient climate control in storage of tulip bulbs. Pilot EB-01; Naar een energiezuiniger klimaatbeheersing bij de bewaring van tulpenbollen. Praktijkproef EB-01

Energy Technology Data Exchange (ETDEWEB)

Gude, H.; Dijkema, M.

2005-09-15

The aim of this project is to enable energy conservation in the storage of tulip bulbs. To this end, it should be examined if the agent EB-01 (1-methylcycloprene, a protection agent for plants) can be used in practical cells that are not entirely leak proof and if it offers sufficient protection against ethylene damage [Dutch] Doel van dit project is om energiebesparing bij de bewaring van tulpenbollen mogelijk te maken. Om dat te realiseren wordt onderzocht of het middel EB-01 (1- methylcyclopropeen, een beschermingsmiddel voor planten) toepasbaar is in niet volledig lekdichte praktijkcellen en voldoende bescherming tegen ethyleenschade biedt.

78 FR 59981 - Proposed Revision to Physical Security-Standard Design Certification and Operating Reactors

Science.gov (United States)

2013-09-30

... Design Certification and Operating Reactors AGENCY: Nuclear Regulatory Commission. ACTION: Standard... Design Certification and Operating Reactors.'' The NRC seeks comments on the proposed revised section of... subject): Federal Rulemaking Web site: Go to http://www.regulations.gov and search for Docket ID NRC-2013...

Why there is a need to revise the design basis threat concept

International Nuclear Information System (INIS)

Kondratov, S.; Steinhaeusler, F.

2005-01-01

Full text: The coordinated terrorist attacks in the United States on September 11, 2001, necessitated the review of the proven concept of the Design Basis Threat (DBT) for nuclear installations. It is safe to assume that revised and upgraded DBT will result in costly technical solutions. Since infrastructure deficits and financial limitations in many countries have already limited the practical application of the DBT in many instances, the revised threat assessment is likely to worsen the current dissatisfactory situation further. Therefore, a new realism in the use of the DBT concept is proposed, based on a three-level approach. This will enable countries to tailor the design of their physical protection systems in accordance with their means by implementing either a minimum required security level protecting only against the most probable threat, or aiming for an intermediate protection level reflecting the newly introduced AHARA - as high as reasonably achievable - principle, or providing the optimum protection level based on an externally reviewed, fully comprehensive DBT. (author)

Why there is a need to revise the Design Basis Threat concept

International Nuclear Information System (INIS)

Kondratov, S.; Steinhausler, F.

2006-01-01

The terrorist attacks in the USA on 11 September 2001 necessitated a review of the proven concept of the Design Basis Threat (DBT) for nuclear installations. It can be assumed that revised and upgraded DBT will result in costly technical solutions. Since infrastructure deficits and financial limitations in many countries have already limited the practical application of the DBT, the revised threat assessment is likely to worsen the current unsatisfactory situation. Therefore, a new realism in the use of the DBT concept is proposed based on a three-level approach. This will enable countries to tailor the design of their physical protection systems in accordance with their means by implementing either a minimum required security level protecting only against the most probable threat, or an intermediate protection level reflecting the newly introduced AHARA (As High As Reasonably Achievable) principle, or the optimum protection level based on an externally reviewed, fully comprehensive DBT. (author)

Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity

Energy Technology Data Exchange (ETDEWEB)

Marreilha dos Santos, A.P., E-mail: apsantos@ff.ul.pt [I-Med.UL, Department of Toxicology and Food Sciences, Faculty of Pharmacy, University of Lisbon, Lisbon (Portugal); Lucas, Rui L.; Andrade, Vanda; Mateus, M. Luísa [I-Med.UL, Department of Toxicology and Food Sciences, Faculty of Pharmacy, University of Lisbon, Lisbon (Portugal); Milatovic, Dejan; Aschner, Michael [Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232 (United States); Batoreu, M. Camila [I-Med.UL, Department of Toxicology and Food Sciences, Faculty of Pharmacy, University of Lisbon, Lisbon (Portugal)

2012-02-01

Chronic, excessive exposure to manganese (Mn) may induce neurotoxicity and cause an irreversible brain disease, referred to as manganism. Efficacious therapies for the treatment of Mn are lacking, mandating the development of new interventions. The purpose of the present study was to investigate the efficacy of ebselen (Ebs) and para-aminosalicylic acid (PAS) in attenuating the neurotoxic effects of Mn in an in vivo rat model. Exposure biomarkers, inflammatory and oxidative stress biomarkers, as well as behavioral parameters were evaluated. Co-treatment with Mn plus Ebs or Mn plus PAS caused a significant decrease in blood and brain Mn concentrations (compared to rats treated with Mn alone), concomitant with reduced brain E{sub 2} prostaglandin (PGE{sub 2}) and enhanced brain glutathione (GSH) levels, decreased serum prolactin (PRL) levels, and increased ambulation and rearing activities. Taken together, these results establish that both PAS and Ebs are efficacious in reducing Mn body burden, neuroinflammation, oxidative stress and locomotor activity impairments in a rat model of Mn-induced toxicity. -- Highlights: ► The manuscript is unique in its approach to the neurotoxicity of Mn. ► The manuscript incorporates molecular, cellular and functional (behavioral) analyses. ► Both PAS and Ebs are effective in restoring Mn behavioral function. ► Both PAS and Ebs are effective in reducing Mn-induced oxidative stress. ► Both PAS and Ebs led to a decrease in Mn-induced neuro-inflammation.

Protective effects of ebselen (Ebs) and para-aminosalicylic acid (PAS) against manganese (Mn)-induced neurotoxicity

International Nuclear Information System (INIS)

Marreilha dos Santos, A.P.; Lucas, Rui L.; Andrade, Vanda; Mateus, M. Luísa; Milatovic, Dejan; Aschner, Michael; Batoreu, M. Camila

2012-01-01

Chronic, excessive exposure to manganese (Mn) may induce neurotoxicity and cause an irreversible brain disease, referred to as manganism. Efficacious therapies for the treatment of Mn are lacking, mandating the development of new interventions. The purpose of the present study was to investigate the efficacy of ebselen (Ebs) and para-aminosalicylic acid (PAS) in attenuating the neurotoxic effects of Mn in an in vivo rat model. Exposure biomarkers, inflammatory and oxidative stress biomarkers, as well as behavioral parameters were evaluated. Co-treatment with Mn plus Ebs or Mn plus PAS caused a significant decrease in blood and brain Mn concentrations (compared to rats treated with Mn alone), concomitant with reduced brain E 2 prostaglandin (PGE 2 ) and enhanced brain glutathione (GSH) levels, decreased serum prolactin (PRL) levels, and increased ambulation and rearing activities. Taken together, these results establish that both PAS and Ebs are efficacious in reducing Mn body burden, neuroinflammation, oxidative stress and locomotor activity impairments in a rat model of Mn-induced toxicity. -- Highlights: ► The manuscript is unique in its approach to the neurotoxicity of Mn. ► The manuscript incorporates molecular, cellular and functional (behavioral) analyses. ► Both PAS and Ebs are effective in restoring Mn behavioral function. ► Both PAS and Ebs are effective in reducing Mn-induced oxidative stress. ► Both PAS and Ebs led to a decrease in Mn-induced neuro-inflammation.

A Application of WD Model to EB Type Contact Binary System

Directory of Open Access Journals (Sweden)

Su-Yeon Oh

2000-12-01

Full Text Available The EB type contact binaries show large temperature difference ( T 1,000K between two components. Thus we have modified the mode 3 of the WD program to adjust albedos, limb darkening coefficients and gravity darkening exponents for both components of such binaries, while the values for those parameters should be same for both components in the original WD program. Both of the modified and the original versions have been applied to the EB type contact binaries such as DO Cas, GO Cyg, and FS Lup. The computed light curves with modified version fit better to the observations.

EB-promoted recycling of waste tire rubber with polyolefins

Science.gov (United States)

Mészáros, László; Bárány, Tamás; Czvikovszky, Tibor

2012-09-01

Despite the fact that more and more methods and solutions are used in the recycling of polymers, there are still some problems, especially in the recycling of cross-linked materials such as rubber. Usually the biggest problem is the lack of compatibility between the cross-linked rubber and the thermoplastic matrix. In this study we applied ground tire rubber (GTR) as recycled material. The GTR was embedded into polyethylene (PE) and polyethylene/ethylene-vinyl acetate copolymer (PE/EVA) matrices. In order to increase the compatibility of the components electron beam (EB) irradiation was applied. The results showed that the irradiation has a beneficial effect on the polymer-GTR interfacial connection. The EB treatment increased not only the tensile strength but also the elongation at break. The irradiation had also positive effect on the impact strength properties.

Engineered barrier systems (EBS) in the context of the entire safety case

International Nuclear Information System (INIS)

2003-01-01

A joint NEA-EC workshop entitled 'Engineered Barrier Systems (EBS) in the Context of the Entire Safety Case' was organised in Oxford on 25-27 September 2002 and hosted by United Kingdom Nirex Limited. The main objectives of the workshop were to provide a status report on engineered barrier systems in various national radioactive waste management programmes considering deep geological disposal; to establish the value to member countries of a project on EBS; and to define such a project's scope, timetable and modus operandi. This report presents the outcomes of this workshop. (author)

Engineered Barrier Systems (EBS) in the Context of the Entire Safety Case

International Nuclear Information System (INIS)

2005-01-01

A joint NEA-EC workshop entitled ''Engineered Barrier Systems (EBS) in the Context of the Entire Safety Case'' was organised in Oxford on 25-27 September 2002 and hosted by United Kingdom Nirex Limited. The main objectives of the workshop were to provide a status report on engineered barrier systems in various national radioactive waste management programmes considering deep geological disposal; to establish the value to member countries of a project on EBS; and to define such a project scope, timetable and modus operandi. This report presents the outcomes of this workshop. (author)

Human-system interface design review guideline -- Review software and user's guide: Final report. Revision 1, Volume 3

International Nuclear Information System (INIS)

1996-06-01

NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant's HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 3 contains an interactive software application of the NUREG-0700, Revision 1 guidance and a user's guide for this software. The software supports reviewers during review preparation, evaluation design using the human factors engineering guidelines, and in report preparation. The user's guide provides system requirements and installation instructions, detailed explanations of the software's functions and features, and a tutorial on using the software

Polyurethane acrylate networks including cellulose nanocrystals: a comparison between UV and EB- curing

International Nuclear Information System (INIS)

Furtak-Wrona, K.; Kozik-Ostrówka, P.; Jadwiszczak, K.; Maigret, J.E.; Aguié-Béghin, V.; Coqueret, X.

2018-01-01

A water-based polyurethane (PUR) acrylate water emulsion was selected as a radiation curable matrix for preparing nanocomposites including cellulose nanocrystals (CNC) prepared by controlled hydrolysis of Ramie fibers. Cross-linking polymerization of samples prepared in the form of films or of 1 mm-thick bars was either initiated by exposure to the 395 nm light of a high intensity LED lamp or by treatment with low energy electron beam (EB). The conversion level of acrylate functions in samples submitted to increasing radiation doses was monitored by Fourier Transform Infrared Spectroscopy (FTIR). Differential Scanning Calorimetry (DSC) and Dynamic Mechanical Analysis (DMA) were used to characterize changes in the glass transition temperature of the PUR-CNC nanocomposites as a function of acrylate conversion and of CNC content. Micromechanical testing indicates the positive effect of 1 wt% CNC on Young's modulus and on the tensile strength at break (σ) of cured nanocomposites. The presence of CNC in the PUR acrylate matrix was shown to double the σ value of the nanocomposite cured to an acrylate conversion level of 85% by treatment with a 25 kGy dose under EB, whereas no increase of σ was observed in UV-cured samples exhibiting the same acrylate conversion level. The occurrence of grafting reactions inducing covalent linkages between the polysaccharide nanofiller and the PUR acrylate matrix during the EB treatment is advanced as an explanation to account for the improvement observed in samples cured under ionizing radiation. - Highlights: • Nanocomposites were prepared from o/w PUR acrylate emulsion and CNC suspension. • Nanocomposite and reference materials were cured to the same conversion by UV or EB. • Introducing 1 wt% CNC in EB-cured composites doubles the tensile strength. • UV-cured nanocomposites did not show significant improvement in tensile strength.

Advanced neutron and X-ray techniques for insights into the microstructure of EB-PVD thermal barrier coatings

Energy Technology Data Exchange (ETDEWEB)

Kulkarni, Anand [State University of New York, Stony Brook, NY 11794 (United States); Goland, Allen [State University of New York, Stony Brook, NY 11794 (United States); Herman, Herbert [State University of New York, Stony Brook, NY 11794 (United States)]. E-mail: hherman@ms.cc.sunysb.edu; Allen, Andrew J. [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States); Dobbins, Tabbetha [National Institute of Standards and Technology, Gaithersburg, MD 20899 (United States); DeCarlo, Francesco [Argonne National Laboratory, Argonne, IL 60439 (United States); Ilavsky, Jan [Argonne National Laboratory, Argonne, IL 60439 (United States); Long, Gabrielle G. [Argonne National Laboratory, Argonne, IL 60439 (United States); Fang, Stacy [Chromalloy Gas Turbine Corporation, Orangeburg, NY 10962 (United States); Lawton, Paul [Chromalloy Gas Turbine Corporation, Orangeburg, NY 10962 (United States)

2006-06-25

The ongoing quest to increase gas turbine efficiency and performance (increased thrust) provides a driving force for materials development. While improved engine design and usage of novel materials provide solutions for increased engine operating temperatures, and hence fuel efficiency, reliability issues remain. Thermal barrier coatings (TBCs), deposited onto turbine components using the electron-beam physical vapor deposition (EB-PVD) process, exhibit unique pore architectures capable of bridging the technological gap between insulation/life extension and prime reliance. This article explores the potential of advanced X-ray and neutron techniques for comprehension of an EB-PVD TBC coating microstructure. While conventional microscopy reveals a hierarchy of voids, complementary advanced techniques allow quantification of these voids in terms of component porosities, anisotropy, size and gradient through the coating thickness. In addition, the derived microstructural parameters obtained both further knowledge of the nature and architecture of the porosity, and help establish its influence on the resultant thermal and mechanical properties.

Current and future market of UV/EB curing in Thailand

International Nuclear Information System (INIS)

Suda Kiatkamjornwong; Aran Hanseubsai

1999-01-01

Current status and future market of UV/EB curing in Thailand were presented. Included number of printing houses, export, main export market and the role of radiation curing in printing and packaging industries of Thailand

Three New Pierce's Disease Pathogenicity Effectors Identified Using Xylella fastidiosa Biocontrol Strain EB92-1.

Science.gov (United States)

Zhang, Shujian; Chakrabarty, Pranjib K; Fleites, Laura A; Rayside, Patricia A; Hopkins, Donald L; Gabriel, Dean W

2015-01-01

Xylella fastidiosa (X. fastidiosa) infects a wide range of plant hosts and causes economically serious diseases, including Pierce's Disease (PD) of grapevines. X. fastidiosa biocontrol strain EB92-1 was isolated from elderberry and is infectious and persistent in grapevines but causes only very slight symptoms under ideal conditions. The draft genome of EB92-1 revealed that it appeared to be missing genes encoding 10 potential PD pathogenicity effectors found in Temecula1. Subsequent PCR and sequencing analyses confirmed that EB92-1 was missing the following predicted effectors found in Temecula1: two type II secreted enzymes, including a lipase (LipA; PD1703) and a serine protease (PD0956); two identical genes encoding proteins similar to Zonula occludens toxins (Zot; PD0915 and PD0928), and at least one relatively short, hemagglutinin-like protein (PD0986). Leaves of tobacco and citrus inoculated with cell-free, crude protein extracts of E. coli BL21(DE3) overexpressing PD1703 exhibited a hypersensitive response (HR) in less than 24 hours. When cloned into shuttle vector pBBR1MCS-5, PD1703 conferred strong secreted lipase activity to Xanthomonas citri, E. coli and X. fastidiosa EB92-1 in plate assays. EB92-1/PD1703 transformants also showed significantly increased disease symptoms on grapevines, characteristic of PD. Genes predicted to encode PD0928 (Zot) and a PD0986 (hemagglutinin) were also cloned into pBBR1MCS-5 and moved into EB92-1; both transformants also showed significantly increased symptoms on V. vinifera vines, characteristic of PD. Together, these results reveal that PD effectors include at least a lipase, two Zot-like toxins and a possibly redundant hemagglutinin, none of which are necessary for parasitic survival of X. fastidiosa populations in grapevines or elderberry.

Three New Pierce's Disease Pathogenicity Effectors Identified Using Xylella fastidiosa Biocontrol Strain EB92-1.

Directory of Open Access Journals (Sweden)

Shujian Zhang

Full Text Available Xylella fastidiosa (X. fastidiosa infects a wide range of plant hosts and causes economically serious diseases, including Pierce's Disease (PD of grapevines. X. fastidiosa biocontrol strain EB92-1 was isolated from elderberry and is infectious and persistent in grapevines but causes only very slight symptoms under ideal conditions. The draft genome of EB92-1 revealed that it appeared to be missing genes encoding 10 potential PD pathogenicity effectors found in Temecula1. Subsequent PCR and sequencing analyses confirmed that EB92-1 was missing the following predicted effectors found in Temecula1: two type II secreted enzymes, including a lipase (LipA; PD1703 and a serine protease (PD0956; two identical genes encoding proteins similar to Zonula occludens toxins (Zot; PD0915 and PD0928, and at least one relatively short, hemagglutinin-like protein (PD0986. Leaves of tobacco and citrus inoculated with cell-free, crude protein extracts of E. coli BL21(DE3 overexpressing PD1703 exhibited a hypersensitive response (HR in less than 24 hours. When cloned into shuttle vector pBBR1MCS-5, PD1703 conferred strong secreted lipase activity to Xanthomonas citri, E. coli and X. fastidiosa EB92-1 in plate assays. EB92-1/PD1703 transformants also showed significantly increased disease symptoms on grapevines, characteristic of PD. Genes predicted to encode PD0928 (Zot and a PD0986 (hemagglutinin were also cloned into pBBR1MCS-5 and moved into EB92-1; both transformants also showed significantly increased symptoms on V. vinifera vines, characteristic of PD. Together, these results reveal that PD effectors include at least a lipase, two Zot-like toxins and a possibly redundant hemagglutinin, none of which are necessary for parasitic survival of X. fastidiosa populations in grapevines or elderberry.

Sensitivity of the engineered barrier system (EBS) release rate to alternative conceptual models of advective release from waste packages under dripping fractures

International Nuclear Information System (INIS)

Lee, J.H.; Atkins, J.E.; McNeish, J.A.; Vallikat, V.

1996-01-01

Simulations were conducted to analyze the sensitivity of the engineered barrier system (EBS) release rate to alternative conceptual models of the advective release from waste packages under dripping fractures. The first conceptual model assumed that dripping water directly contacts the waste form inside the 'failed' waste package, and radionuclides are released from the EBS by advection. The second conceptual model assumed that dripping water is diverted around the 'failed' waste package (because of the presence of corrosion products plugging the perforations) and dripping water is prevented from directly contacting the waste form. In the second model, radionuclides were assumed to transport through the perforations by diffusion, and, once outside the waste package, to be released from the EBS by advection. The second model was to incorporate more realism into the EBS release calculations. For the case with the second EBS release model, most radionuclides had significantly lower peak EBS release rates (from at least one to several orders of magnitude) than with the first EBS release model. The impacts of the alternative EBS release models were greater for the radionuclides with a low solubility (or solubility-limited radionuclides) than for the radionuclides with a high solubility (or waste form dissolution-limited radionuclides). The analyses indicated that the EBS release model representing advection through a 'failed' waste package (the first EBS release model) may be too conservative in predicting the EBS performance. One major implication from this sensitivity study was that a 'failed' waste package container with multiple perforations may still be able to perform effectively as an important barrier to radionuclide release. (author)

Current status of low energy EB machine

International Nuclear Information System (INIS)

Toshiro Nishikimi; Shuichi Taniguchi; Kenichi Mizusawa

1999-01-01

Electron beam processing systems have been in use in a variety of applications such as curing of paints and printing inks, crosslinking of PE products, treating of rubber tire and so on. Low energy electron processing systems have become popular as self-shielded machines, which are compact and easy to use and do not require special facility as an irradiation room. This manuscript introduces the status of low energy EB (electron beam) machine through Nissin's products current

Anti-migratory effect of vinflunine in endothelial and glioblastoma cells is associated with changes in EB1 C-terminal detyrosinated/tyrosinated status.

Directory of Open Access Journals (Sweden)

Amandine Rovini

Full Text Available We previously showed that vinflunine, a microtubule-targeting drug of the Vinca-alkaloid family exerted its anti-angiogenic/anti-migratory activities through an increase in microtubule dynamics and an inhibition of microtubule targeting to adhesion sites. Such effect was associated with a reduction of EB1 comet length at microtubule (+ ends. In this work we first showed that the pro-angiogenic vascular endothelial growth factor VEGF suppressed microtubule dynamics in living Human Umbilical Vein Endothelial Cells (HUVECs, increased EB1 comet length by 40%, and induced EB1 to bind all along the microtubules, without modifying its expression level. Such microtubule (+ end stabilization occurred close to the plasma membrane in the vicinity of focal adhesion as shown by TIRF microscopy experiments. Vinflunine completely abolished the effect of VEGF on EB1 comets. Interestingly, we found a correlation between the reduction of EB1 comet length by vinflunine and the inhibition of cell migration. By using 2D gel electrophoresis we demonstrated for the first time that EB1 underwent several post-translational modifications in endothelial and tumor cells. Particularly, the C-terminal EEY sequence was poorly detectable in control and VEGF-treated HUVECs suggesting the existence of a non-tyrosinated form of EB1. By using specific antibodies that specifically recognized and discriminated the native tyrosinated form of EB1 and a putative C-terminal detyrosinated form, we showed that a detyrosinated form of EB1 exists in HUVECs and tumor cells. Interestingly, vinflunine decreased the level of the detyrosinated form and increased the native tyrosinated form of EB1. Using 3-L-Nitrotyrosine incorporation experiments, we concluded that the EB1 C-terminal modifications result from a detyrosination/retyrosination cycle as described for tubulin. Altogether, our results show that vinflunine inhibits endothelial cell migration through an alteration of EB1 comet length

Human-system interface design review guideline -- Process and guidelines: Final report. Revision 1, Volume 1

International Nuclear Information System (INIS)

1996-06-01

NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant's HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 1 consists of two major parts. Part 1 describes those aspects of the review process of the HSI design that are important to identifying and resolving human engineering discrepancies. Part 2 contains detailed guidelines for a human factors engineering review which identify criteria for assessing the implementation of an applicant's or licensee's HSI design

Dissecting the nanoscale distributions and functions of microtubule-end-binding proteins EB1 and ch-TOG in interphase HeLa cells.

Directory of Open Access Journals (Sweden)

Satoko Nakamura

Full Text Available Recently, the EB1 and XMAP215/TOG families of microtubule binding proteins have been demonstrated to bind autonomously to the growing plus ends of microtubules and regulate their behaviour in in vitro systems. However, their functional redundancy or difference in cells remains obscure. Here, we compared the nanoscale distributions of EB1 and ch-TOG along microtubules using high-resolution microscopy techniques, and also their roles in microtubule organisation in interphase HeLa cells. The ch-TOG accumulation sites protruded ∼100 nm from the EB1 comets. Overexpression experiments showed that ch-TOG and EB1 did not interfere with each other's localisation, confirming that they recognise distinct regions at the ends of microtubules. While both EB1 and ch-TOG showed similar effects on microtubule plus end dynamics and additively increased microtubule dynamicity, only EB1 exhibited microtubule-cell cortex attachment activity. These observations indicate that EB1 and ch-TOG regulate microtubule organisation differently via distinct regions in the plus ends of microtubules.

Mechanism design for refunding emissions payment

Energy Technology Data Exchange (ETDEWEB)

Hagem, Cathrine; Holtsmark, Bjart; Sterner, Thomas

2012-07-01

We analyze two mechanism designs for refunding emission payments to polluting firms; Output Based (OB) and Expenditure Based (EB) refunding. In both instruments, emissions fees are returned to the polluting industry, possibly making the policy more easily accepted by policymakers than a standard tax. The crucial difference between OB and EB is that the fees are refunded in proportion to output in the former, but in proportion to the firms' expenditure on abatement equipment in the latter. We show that to achieve a given abatement target, the fee level in the OB design exceeds the standard tax rate, whereas the fee level in the EB design is lower. Furthermore, the use of OB and EB refunding may lead to large differences in the distribution of costs across firms. Both designs do, strictly speaking, imply a cost-ineffective provision of abatement as firms put relatively too much effort into reducing emissions through abatement technology compared with emission reductions through reduced output. However, this may be seen as an advantage by policymakers if they seek to avoid activity reduction in the regulated sector. We provide some numerical illustrations based on abatement cost information from the Norwegian NOx fund.(Author)

Recent advances in application of EB Technology

Energy Technology Data Exchange (ETDEWEB)

Mittendorfer, J [Mediscan GmbH, Kremsmuenster (Austria)

2001-07-01

In this paper recent advances in application of electron beam technology are presented. Important industrial and scientific achievements of the international community, together with research by Mediscan, Austria, an operator of state-of-the-art electron beam service center and innovator in the field of EB-Technology are reviewed. In addition, areas which may play an important role in the future are identified. Special focus is on the use of X-ray converters and the potential for industrial applications. (author)

Recent advances in application of EB Technology

International Nuclear Information System (INIS)

Mittendorfer, J.

2001-01-01

In this paper recent advances in application of electron beam technology are presented. Important industrial and scientific achievements of the international community, together with research by Mediscan, Austria, an operator of state-of-the-art electron beam service center and innovator in the field of EB-Technology are reviewed. In addition, areas which may play an important role in the future are identified. Special focus is on the use of X-ray converters and the potential for industrial applications. (author)

Implementation of KoHLT-EB DAQ System using compact RIO with EPICS

Energy Technology Data Exchange (ETDEWEB)

Chang, Dae-Sik; Kim, Suk-Kwon; Lee, Dong Won [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Cho, Seungyon [National Fusion Research Institute, Daejeon (Korea, Republic of)

2016-10-15

EPICS (Experimental Physics and Industrial Control System) is a collection of software tools collaboratively developed which can be integrated to provide a comprehensive and scalable control system. Currently there is an increase in use of such systems in large Physics experiments like KSTAR, ITER and DAIC (Daejeon Accelerator Ion Complex). The Korean heat load test facility (KoHLT-EB) was installed at KAERI. This facility is utilized for a qualification test of the plasma facing component (PFC) for the ITER first wall and DEMO divertor, and the thermo-hydraulic experiments. The existing data acquisition device was Agilent 34980A multifunction switch and measurement unit and controlled by Agilent VEE. In the present paper, we report the EPICS based newly upgraded KoHLT-EB DAQ system which is the advanced data acquisition system using FPGA-based reconfigurable DAQ devices like compact RIO. The operator interface of KoHLT-EB DAQ system is composed of Control-System Studio (CSS) and another server is able to archive the related data using the standalone archive tool and the archiveviewer can retrieve that data at any time in the infra-network.

A revision of the Cask Designers Guide for the '90s

International Nuclear Information System (INIS)

Shappert, L.B.; Green, V.M.

1992-01-01

The report A Guide for the Design Fabrication, and Operation of Shipping Casks for Nuclear Applications, ORNL-NSIC-68, commonly called the Cask Designers Guide, is being revised at the request of the Transportation and Packaging Safety Division of the Department of Energy (DOE). The new document will be called the Packaging Handbook. The Cask Designers Guide was published in 1970 during the period when many radioactive materials packagings were being developed and many technical studies applicable to these packagings were being performed. Since that period, many improvements in packaging design have appeared, designers have improved their calculational techniques, and much effort has gone into applying Quality Assurance (QA) principles to cask development Materials, and their limitations, have surfaced as a very important consideration in the licensing process. While the Packaging Handbook considers all Type B packages, most of the authors' experience lies in the technical areas found in the licensing of spent nuclear fuel (SNF) packagings and this is reflected in the document

Thermal cycling behaviour of lanthanum zirconate as EB-PVD thermal barrier coating

International Nuclear Information System (INIS)

Bobzin, K.; Lugscheider, E.; Bagcivan, N.

2006-01-01

Thermal cycling tests with two different EB-PVD thermal barrier coatings (TBC) were performed in a furnace cycle test. The results of these tests showed an increase of endurable cycle number when pyrochloric La 2 Zr 2 O 7 was used as TBC. 1865 cycles were reached with La 2 Zr 2 O 7 and 1380 cycles with 7 weigth-% yttria stabilised zirconia (YSZ) EB-PVD TBC. Additional investigation was made with scanning electron microscope (SEM) to investigate morphology and to determine chemical composition by electron dispersive x-ray spectroscopy (EDS) analysis. X-Ray diffraction was performed to analyze structural constitution of deposited coatings. (Abstract Copyright [2006], Wiley Periodicals, Inc.)

Human-system interface design review guideline -- Reviewer`s checklist: Final report. Revision 1, Volume 2

Energy Technology Data Exchange (ETDEWEB)

NONE

1996-06-01

NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant`s HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 2 is a complete set of the guidelines contained in Volume 1, Part 2, but in a checklist format that can be used by reviewers to assemble sets of individual guidelines for use in specific design reviews. The checklist provides space for reviewers to enter guidelines evaluations and comments.

Cooperative Interactions between 480 kDa Ankyrin-G and EB Proteins Assemble the Axon Initial Segment.

Science.gov (United States)

Fréal, Amélie; Fassier, Coralie; Le Bras, Barbara; Bullier, Erika; De Gois, Stéphanie; Hazan, Jamilé; Hoogenraad, Casper C; Couraud, François

2016-04-20

The axon initial segment (AIS) is required for generating action potentials and maintaining neuronal polarity. Significant progress has been made in deciphering the basic building blocks composing the AIS, but the underlying mechanisms required for AIS formation remains unclear. The scaffolding protein ankyrin-G is the master-organizer of the AIS. Microtubules and their interactors, particularly end-binding proteins (EBs), have emerged as potential key players in AIS formation. Here, we show that the longest isoform of ankyrin-G (480AnkG) selectively associates with EBs via its specific tail domain and that this interaction is crucial for AIS formation and neuronal polarity in cultured rodent hippocampal neurons. EBs are essential for 480AnkG localization and stabilization at the AIS, whereas 480AnkG is required for the specific accumulation of EBs in the proximal axon. Our findings thus provide a conceptual framework for understanding how the cooperative relationship between 480AnkG and EBs induces the assembly of microtubule-AIS structures in the proximal axon. Neuronal polarity is crucial for the proper function of neurons. The assembly of the axon initial segment (AIS), which is the hallmark of early neuronal polarization, relies on the longest 480 kDa ankyrin-G isoform. The microtubule cytoskeleton and its interacting proteins were suggested to be early key players in the process of AIS formation. In this study, we show that the crosstalk between 480 kDa ankyrin-G and the microtubule plus-end tracking proteins, EBs, at the proximal axon is decisive for AIS assembly and neuronal polarity. Our work thus provides insight into the functional mechanisms used by 480 kDa ankyrin-G to drive the AIS formation and thereby to establish neuronal polarity. Copyright © 2016 the authors 0270-6474/16/364421-13$15.00/0.

EB curing of oxidative-polymerized linseed oil

International Nuclear Information System (INIS)

Ju Xuecheng; Ha Hongfei

2000-01-01

The properties of EB curing coating films, which were determined by the structure of oxidative-polymerized linseed oil, were as following: good gloss, low hardness, better flexibility and impact resistance, low glass transition temperature and bad adhesion on tinplate. Oxidative-polymerized linseed oil could be used with other compositions not only as oligomer, but also as functional monomer to improve the properties of coating films of composite systems. Both absorbed dose sand Cobaltous naphthenate had little influence on the properties of these coating films

The Format Converting/Transfer Agent and Repository System based on ebXML

Directory of Open Access Journals (Sweden)

KyeongRim Ahn

2004-12-01

Full Text Available As introducing XML in EC-environment, various document formats have been used due to XML characteristic. Also, other document format except XML have been used to exchange EC-related information. That is, as increasing trading partner, as increasing exchanged document format and business processing being complex. So, management difficulty and duplication problem happened as trading partners increasing. And, they want to change plural business workflow to general and uniform form as defining and arranging BP(Business Process. Therefore, in this paper, we define XML as future document standard agreement and discuss about service system architecture and Repository. Repository stores and manages document standard, information related to Business Processing, Messaging Profile, and so on. Repository structure is designed to cover various XML standards. Also, we design system to support ebXML communication protocol, MSH, as well as traditional communication protocol, such as X.25, X.400, etc. and implement to exchange information via FTP.

Overview of UV and EB curing

International Nuclear Information System (INIS)

Garnett, J.L.

2000-01-01

Full text: UV and EB are complementary techniques in radiation curing. In the proposed paper, a brief review of both fields will be given. This will include principles of the process, the chemistry of the systems including monomers/oligomers/polymers used, additives required where necessary such as photoinitiators for UV, flow aids, adhesion promoters and the like. The types of equipment used in such processes will also be discussed including low energy electron beam utilisation and excimer curing. The advantages and disadvantages of both techniques will be examined. Mechanistic aspects of both curing systems will be discussed. Applications of the technology including developments in the banknote printing field will be summarised

Human-system interface design review guideline -- Process and guidelines: Final report. Revision 1, Volume 1

Energy Technology Data Exchange (ETDEWEB)

None

1996-06-01

NUREG-0700, Revision 1, provides human factors engineering (HFE) guidance to the US Nuclear Regulatory Commission staff for its: (1) review of the human system interface (HSI) design submittals prepared by licensees or applications for a license or design certification of commercial nuclear power plants, and (2) performance of HSI reviews that could be undertaken as part of an inspection or other type of regulatory review involving HSI design or incidents involving human performance. The guidance consists of a review process and HFE guidelines. The document describes those aspects of the HSI design review process that are important to the identification and resolution of human engineering discrepancies that could adversely affect plant safety. Guidance is provided that could be used by the staff to review an applicant`s HSI design review process or to guide the development of an HSI design review plan, e.g., as part of an inspection activity. The document also provides detailed HFE guidelines for the assessment of HSI design implementations. NUREG-0700, Revision 1, consists of three stand-alone volumes. Volume 1 consists of two major parts. Part 1 describes those aspects of the review process of the HSI design that are important to identifying and resolving human engineering discrepancies. Part 2 contains detailed guidelines for a human factors engineering review which identify criteria for assessing the implementation of an applicant`s or licensee`s HSI design.

Sensitivity of the engineered barrier system (EBS) release rate to alternative conceptual models of advective release from waste packages under dripping fractures

International Nuclear Information System (INIS)

Lee, J.H.; Atkins, J.E.; McNeish, J.A.; Vallikat, V.

1996-01-01

The first model assumed that dripping water directly contacts the waste form inside the ''failed'' waste package and radionuclides are released from the EBS by advection. The second model assumed that dripping water is diverted around the package (because of corrosion products plugging the perforations), thereby being prevented from directly contacting the waste form. In the second model, radionuclides were assumed to diffuse through the perforations, and, once outside the waste package, to be released from the EBS by advection. For the case with the second EBS release model, most radionuclides had lower peak EBS release rates than with the first model. Impacts of the alternative EBS release models were greater for the radionuclides with low solubility. The analysis indicated that the EBS release model representing advection through a ''failed'' waste package (the first model) may be too conservative; thus a ''failed'' waste package container with multiple perforations may still be an important barrier to radionuclide release

Microstructural, mechanical and oxidation features of NiCoCrAlY coating produced by plasma activated EB-PVD

International Nuclear Information System (INIS)

He, Jian; Guo, Hongbo; Peng, Hui; Gong, Shengkai

2013-01-01

NiCoCrAlY coatings produced by electron beam-physical vapor deposition (EB-PVD) have been extensively used as the oxidation resistance coatings or suitable bond coats in thermal barrier coating (TBC) system. However, the inherent imperfections caused by EB-PVD process degrade the oxidation resistance of the coatings. In the present work, NiCoCrAlY coatings were creatively produced by plasma activated electron beam-physical vapor deposition (PA EB-PVD). The novel coatings showed a terraced substructure on the surface of each grain due to the increased energy of metal ions and enhanced mobility of adatoms. Also a strong (1 1 1) crystallographic texture of γ/γ′ grains was observed. The toughness of the coatings got remarkably improved compared with the coatings deposited by conventional EB-PVD and the oxidation behavior at 1373 K showed that the novel coatings had excellent oxidation resistance. The possible mechanism was finally discussed.

76 FR 1192 - Notice of a Change in Status of an Extended Benefit (EB) Period for Puerto Rico

Science.gov (United States)

2011-01-07

... Extended Benefit (EB) Period for Puerto Rico AGENCY: Employment and Training Administration, Labor. ACTION... Puerto Rico. The following change has occurred since the publication of the last notice regarding the State's EB status: Puerto Rico's 13-week IUR has fallen below the 6% threshold and does not equal or...

Sintering and microstructure evolution of columnar nickel-based superalloy sheets prepared by EB-PVD

International Nuclear Information System (INIS)

Chen, S.; Qu, S.J.; Liang, J.; Han, J.C.

2010-01-01

Research highlights: → EB-PVD technology is commonly used to deposit thermal barrier coatings (TBCs) and columnar structure is commonly seen in EB-PVD condensates. The unique columnar structure can provide outstanding resistance against thermal shock and mechanical strains for TBCs. However, a number of researchers have found that the columnar structure can affect the mechanical properties of EB-PVD alloy thin sheet significantly. As yet, works on how to reduce this kind of effects are seldom done. In the present article, we tried to reveal the sintering effects on microstructure evolution and mechanical properties of columnar Ni-based superalloy sheet. The results suggests that after sintering, the columnar structure degrades. Degradation depends on sintering temperature and time. Both the ultimate tensile strength and the elongation percentage are effectively improved after sintering. - Abstract: A ∼0.15 mm-thick columnar nickel-based superalloy sheet was obtained by electron beam physical vapor deposition (EB-PVD). The as-deposited alloy sheet was sintered at different conditions. The microstructure of the specimens before and after sintering was characterized by using scanning electron microscopy. An X'Pert texture facility was used to determine the crystallographic orientation of the as-deposited alloy sheet. The phase transformation was investigated by X-ray diffraction. Tensile tests were conducted at room temperature on as-deposited and sintered specimens. The results show that the as-deposited sheet is composed of typical columnar structures. After sintering, however, the columnar structure degrades. The degradation depends on sintering temperature and time. Both the ultimate tensile strength and the elongation percentage are effectively improved after sintering.

Creep properties of EB welded copper overpack at 125-175 deg C

International Nuclear Information System (INIS)

Holmstroem, S.; Salonen, J.; Kinnunen, T.

2012-01-01

Electron Beam welds (EBW) chosen as primary sealing method by Posiva welding the over-pack canister lids of oxygen-free phosphorus micro-alloyed copper (OFP) have been tested for material properties relevant to long term creep life prediction. Creep rupture results are presented for the ruptured 175 deg C tests and for the ongoing long term tests at 150 deg C and 125 deg C. The current status (test time, creep strain and strain rate) of the ongoing tests are reported. The initial (175 deg C) results indicate that the EB welds are weaker than the parent material and that both round bar and spark eroded square test specimens produce weld strengths of about 0.75 at tests durations of 5000 h. The downward trend is however expected to continue for the longer test durations. The creep ductility shows decrease for the longer tests. Life estimates for the EB weld have been calculated at 100 deg C for both 50 and 80 MPa with the so far lowest measured EB weld strength factor (WSF=0.77). The state-of-the-art model on the available data give estimated lives of 21000 and 3000 years correspondingly. However, simulated to the expected temperature profile of the repository service the life fraction reached after 10000 years of service is 1 % and 7 % for the same stress levels. It is though important to remembered that the 80 MPa assumption is very conservative in nature and that the predictions do not take into account relaxation of stresses, further decline of the WSF or anisotropy of the weld and are therefore still to be considered indicative only. It is also to be remembered that there is only limited data in the long term regime for the weldments and that the estimates are based on the few EB data available in the public domain added with the Posiva data of this project. Improvement of the models and predictions are expected from the ongoing 125 deg C and 150 deg C long term tests. (orig.)

NiCoCrAl/YSZ laminate composites fabricated by EB-PVD

International Nuclear Information System (INIS)

Shi Guodong; Wang Zhi; Liang Jun; Wu Zhanjun

2011-01-01

Highlights: → The metal-ceramic laminate composites were fabricated by EB-PVD. → Both metal and ceramic layers consisted of straight columns with banded structures. → Columnar grain size was limited by the periodic layer interfaces in the laminates. → Effect of columns on fracture property was decreased by limiting layer thickness. → Laminates showed greater specific strength than monolithic metal foil. - Abstract: Two NiCoCrAl/YSZ laminate composites (A and B) with different metal-layer thickness (∼35 μm and 14 μm, respectively) were fabricated by electron beam physical vapor deposition (EB-PVD). Their microstructure was examined and their mechanical properties were compared with the 289 μm thick NiCoCrAl monolithic foil produced by EB-PVD. Both the YSZ and NiCoCrAl layers of the laminate composites had columnar grain structure. But the periodic layer interfaces limited the columnar grain size. Some pores between the columns were also observed. It was found that the strength of the laminate A was equal approximately to that of the NiCoCrAl monolithic foil, and that laminate B had the greater strength. Moreover, the density of the foils decreased with the increasing thickness ratio of YSZ/NiCoCrAl layers and the increasing the layer number. Thus, comparing with the NiCoCrAl monolithic foil, the NiCoCrAl/YSZ laminate composites not only had the equal or greater strength, but also had the much greater specific strength.

Microcomputers and the Improvement of Revision Skills.

Science.gov (United States)

Balajthy, Ernest; And Others

1987-01-01

Discusses use of word processing software as an effective tool in writing and revision instruction, and describes the role of the teacher. Examples of exercises that encourage revision and of software designed to teach effective revision skills are reviewed. (MBR)

Practice Study Outpatient Psychotherapy - Switzerland (PAP-S) : Study design and feasibility (Revised edition)

OpenAIRE

Wyl, Agnes von; Crameri, Aureliano; Koemeda, Margit; Tschuschke, Volker; Schulthess, Peter

2016-01-01

Revised edition of Von Wyl, A., Crameri, A., Koemeda, M., Tschuchke, V. & Schulthess, P. (2013). The PAP-S (Practice of Ambulant Psychotherapy-Study), Switzerland: Study Design and Feasibility. Zurich University of Applied Sciences, Zurich. The original article was published in German: von Wyl, A., Crameri, A., Koemeda, M., Tschuschke, V. & Schulthess, P. (2013). Praxisstudie ambulante Psychotherapie Schweiz (PAP-S): Studiendesign und Machbarkeit. Psychotherapie-Wissenschaft, 1, 6-22; op...

Primary study on synthesis and characterization of the new type EB curable resins. Pt.1: Acrylic resins modified by light-oil

International Nuclear Information System (INIS)

Wei Jinshan; Yi Min; Wang Ruiyu; Li Jun; Ha Hongfei

1995-01-01

An acrylic resin modified by vegetable oil with high degree of unsaturation level has been synthesized. The characterization of coating film EB cured by the modified acrylic resin was studied primarily. The new type of EB curable acrylic resin is possessed of many merits such as cheap raw materials, simple synthesis technique and pretty characteristics of coating film. It is especially fit for timber surface coatings cured by EB radiation

Akap350 Recruits Eb1 to The Spindle Poles, Ensuring Proper Spindle Orientation and Lumen Formation in 3d Epithelial Cell Cultures.

Science.gov (United States)

Almada, Evangelina; Tonucci, Facundo M; Hidalgo, Florencia; Ferretti, Anabela; Ibarra, Solange; Pariani, Alejandro; Vena, Rodrigo; Favre, Cristián; Girardini, Javier; Kierbel, Arlinet; Larocca, M Cecilia

2017-11-02

The organization of epithelial cells to form hollow organs with a single lumen requires the accurate three-dimensional arrangement of cell divisions. Mitotic spindle orientation is defined by signaling pathways that provide molecular links between specific spots at the cell cortex and astral microtubules, which have not been fully elucidated. AKAP350 is a centrosomal/Golgi scaffold protein, implicated in the regulation of microtubule dynamics. Using 3D epithelial cell cultures, we found that cells with decreased AKAP350 expression (AKAP350KD) formed polarized cysts with abnormal lumen morphology. Analysis of mitotic cells in AKAP350KD cysts indicated defective spindle alignment. We established that AKAP350 interacts with EB1, a microtubule associated protein that regulates spindle orientation, at the spindle poles. Decrease of AKAP350 expression lead to a significant reduction of EB1 levels at spindle poles and astral microtubules. Conversely, overexpression of EB1 rescued the defective spindle orientation induced by deficient AKAP350 expression. The specific delocalization of the AKAP350/EB1complex from the centrosome decreased EB1 levels at astral microtubules and lead to the formation of 3D-organotypic structures which resembled AKAP350KD cysts. We conclude that AKAP350 recruits EB1 to the spindle poles, ensuring EB1 presence at astral microtubules and proper spindle orientation during epithelial morphogenesis.

EBS/C proton spectra from a virgin diamond crystal

Energy Technology Data Exchange (ETDEWEB)

Erich, M., E-mail: marko.erich@gmail.com [Laboratory of Physics, Vinča Institute of Nuclear Sciences, University of Belgrade, PO Box 552, Belgrade (Serbia); Kokkoris, M. [Department of Physics, National Technical University of Athens, Zografou Campus 157 80, Athens (Greece); Fazinić, S. [Laboratory for Ion Beam Interactions, Department of Experimental Physics, Institute Ruđer Bošković, Bijenička cesta 54, 10000 Zagreb (Croatia); Petrović, S. [Laboratory of Physics, Vinča Institute of Nuclear Sciences, University of Belgrade, PO Box 552, Belgrade (Serbia)

2016-08-15

In the present work, elastic backscattering channeling spectra, EBS/C, of protons in a 〈1 0 0〉 diamond crystal were experimentally and theoretically studied via a new computer simulation code. Proton incident energies for EBS/C spectra were in the energy range from 1.0 MeV to 1.9 MeV. The energy range was chosen in order to explore a distinct strong resonance of the {sup 12}C(p,p{sub 0}){sup 12}C elastic scattering at 1737 keV. The computer simulation code applied for the fitting of the experimental spectra in the random mode was compared with the corresponding SIMNRA results. In the channeling mode, it assumes a Gompertz type sigmoidal dechanneling function, which has two fitting parameters, x{sub c} and k, the dechanneling range and rate, respectively. It also uses α, ratio of the channeling to random energy losses, as a fitting parameter. It was observed that x{sub c} increases, k decreases and α stays relatively constant with the proton incident energy. These observations confirm the physical interpretation of the fitting parameters. Also, they constitute the basics for the further development of the code for the quantification of induced amorphization and depth profiling of implanted ions.

EB-promoted recycling of waste tire rubber with polyolefins

International Nuclear Information System (INIS)

Mészáros, László; Bárány, Tamás; Czvikovszky, Tibor

2012-01-01

Despite the fact that more and more methods and solutions are used in the recycling of polymers, there are still some problems, especially in the recycling of cross-linked materials such as rubber. Usually the biggest problem is the lack of compatibility between the cross-linked rubber and the thermoplastic matrix. In this study we applied ground tire rubber (GTR) as recycled material. The GTR was embedded into polyethylene (PE) and polyethylene/ethylene-vinyl acetate copolymer (PE/EVA) matrices. In order to increase the compatibility of the components electron beam (EB) irradiation was applied. The results showed that the irradiation has a beneficial effect on the polymer–GTR interfacial connection. The EB treatment increased not only the tensile strength but also the elongation at break. The irradiation had also positive effect on the impact strength properties. - Highlights: ► In this study ground tire rubber was incorporated into polyethylene (LDPE) matrix. ► Compatibilizing effects of irradiation and ethylene-vinyl acetate were investigated. ► The samples were manufactured by twin-screw extrusion and injection molding. ► Both compatibilizing methods improved the rubber-like properties of the blends. ► This improvement was especially significant when they were applied together.

Draft revision of human factors guideline HF-010

International Nuclear Information System (INIS)

Lee, Hyun Chul; Lee, Yong Hee; Oh, In Seok; Lee, Jung Woon; Cha, Woo Chang; Lee, Dhong Ha

2003-05-01

The Application of Human Factors to the design of Man-Machine Interfaces System(MMIS) in the nuclear power plant is essential to the safety and productivity of the nuclear power plants, human factors standards and guidelines as well as human factors analysis methods and experiments are weightily used to the design application. A Korean engineering company has developed a human factors engineering guideline, so-call HF-010, and has used it for human factors design, however the revision of HF-010 is necessary owing to lack of the contents related to the advanced MMI(Man-Machine Interfaces). As the results of the reviews of HF-010, it is found out that the revision of Section 9. Computer Displays of HF-010 is urgent, thus the revision was drafted on the basis of integrated human factors design guidelines for VDT, human factors design guidelines for PMAS SPADES display, human factors design guidelines for PMAS alarm display, and human factors design guidelines for electronic displays developed by the surveillance and operation support project of KOICS. The draft revision of HF-010 Section 9 proposed in this report can be utilized for the human factors design of the advanced MMI, and the high practical usability of the draft can be kept up through the continuous revision according to the advancement of digital technology

Revising an Engineering Design Rubric: A Case Study Illustrating Principles and Practices to Ensure Technical Quality of Rubrics

Directory of Open Access Journals (Sweden)

Gail Lynn Goldberg

2014-08-01

Full Text Available This article provides a detailed account of a rubric revision process to address seven common problems to which rubrics are prone: lack of consistency and parallelism; the presence of - orphan- and - widow- words and phrases; redundancy in descriptors; inconsistency in the focus of qualifiers; limited routes to partial credit; unevenness in incremental levels of performance; and inconsistencies across suites or sets of related rubrics. The author uses examples from both the draft stage precursor and the first revised (pilot version of the Engineering Design Process Portfolio Scoring Rubric (EDPPSR, to illustrate the application of broadly relevant guidelines that can inform the creation of a new-'or revision of an existing-'rubric to achieve technical quality while preserving content integrity

Potential for radionuclide immobilization in the EBS/NFE: solubility limiting phases for neptunium, plutonium, and uranium

Energy Technology Data Exchange (ETDEWEB)

Rard, J. A., LLNL

1997-10-01

Retardation and dispersion in the far field of radionuclides released from the engineered barrier system/near field environment (EBS/NFE) may not be sufficient to prevent regulatory limits being exceeded at the accessible environment. Hence, a greater emphasis must be placed on retardation and/or immobilization of radionuclides in the EBS/NFE. The present document represents a survey of radionuclide-bearing solid phases that could potentially form in the EBS/NFE and immobilize radionuclides released from the waste package and significantly reduce the source term. A detailed literature search was undertaken for experimental solubilities of the oxides, hydroxides, and various salts of neptunium, plutonium, and uranium in aqueous solutions as functions of pH, temperature, and the concentrations of added electrolytes. Numerous solubility studies and reviews were identified and copies of most of the articles were acquired. However, this project was only two months in duration, and copies of some the identified solubility studies could not be obtained at short notice. The results of this survey are intended to be used to assess whether a more detailed study of identified low- solubility phase(s) is warranted, and not as a data base suitable for predicting radionuclide solubility. The results of this survey may also prove useful in a preliminary evaluation of the efficacy of incorporating chemical additives to the EBS/NFE that will enhance radionuclide immobilization.

Effective data compaction algorithm for vector scan EB writing system

Science.gov (United States)

Ueki, Shinichi; Ashida, Isao; Kawahira, Hiroichi

2001-01-01

We have developed a new mask data compaction algorithm dedicated to vector scan electron beam (EB) writing systems for 0.13 μm device generation. Large mask data size has become a significant problem at mask data processing for which data compaction is an important technique. In our new mask data compaction, 'array' representation and 'cell' representation are used. The mask data format for the EB writing system with vector scan supports these representations. The array representation has a pitch and a number of repetitions in both X and Y direction. The cell representation has a definition of figure group and its reference. The new data compaction method has the following three steps. (1) Search arrays of figures by selecting pitches of array so that a number of figures are included. (2) Find out same arrays that have same repetitive pitch and number of figures. (3) Search cells of figures, where the figures in each cell take identical positional relationship. By this new method for the mask data of a 4M-DRAM block gate layer with peripheral circuits, 202 Mbytes without compaction was highly compacted to 6.7 Mbytes in 20 minutes on a 500 MHz PC.

Mainstreaming Ecosystem Services Based Climate Change Adaptation (EbA in Bangladesh: Status, Challenges and Opportunities

Directory of Open Access Journals (Sweden)

Nazmul Huq

2017-06-01

Full Text Available The paper aims to analyze the extent of Ecosystem Service (ESS based Adaptation (EbA to climate change in the policy-making process of Bangladesh. The paper is based on a three stage hybrid policy-making cycle: (i agenda setting; (ii policy formulation; and (iii policy implementation stage, where the contributions of EbA can horizontally (on the ground or vertically (strategic stage be mainstreamed and integrated. A total of nine national and sectoral development and climate change policies, and 329 climate change adaptation projects are examined belonging to different policy-making stages. The major findings include that the role of ESS is marginally considered as an adaptation component in most of the reviewed policies, especially at the top strategic level (vertical mainstreaming. However, at the policy formulation and implementation stage (horizontal mainstreaming, they are largely ignored and priority is given to structural adaptation policies and projects, e.g., large scale concrete dams and embankments. For example, ESS’s roles to adapt sectors such as urban planning, biodiversity management and disaster risk reduction are left unchecked, and the implementation stage receives overwhelming priorities and investments to undertake hard adaptation measures such that only 38 projects are related to EbA. The paper argues that: (i dominant structural adaptation ideologies; (ii the expert and bureaucracy dependent policy making process; and (iii the lack of adaptive and integration capacities at institutional level are considerably offsetting the EbA mainstreaming process that need to be adequately addressed for climate change adaptation.

33 CFR 66.05-10 - State waters for private aids to navigation; designations; revisions, and revocations.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false State waters for private aids to... Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY AIDS TO NAVIGATION PRIVATE AIDS TO NAVIGATION State Aids to Navigation § 66.05-10 State waters for private aids to navigation; designations; revisions, and...

Primary study on synthesis and characterization of the new type EB curable resins. Pt.2: Alkyd resins modified by LFA

International Nuclear Information System (INIS)

Yi Min; Wei Jinshan; Li Jun; Wang Ruiyu; Ha Hongfei

1995-01-01

The authors have synthesized a new type of EB curable resin by using oil fatty acid. The preparation method of coating and the performance of EB curing coating film were described. The synthesis process has been simplified and the price of the raw materials was lower

Yucca Mountain near-field environment considerations for engineered barrier system design and performance

International Nuclear Information System (INIS)

Wilder, D.G.

1991-05-01

The United States Department of Energy (DOE) is investigating the suitability of Yucca Mountain (YM) as a potential site for the nation's first High-Level Nuclear Waste Repository. This responsibility includes materials testing and selections, design criteria development, waste form characterizations, performance assessments, and Near-Field (NF) environment characterization. These areas of responsibility are interrelated and to a large extent depend on environmental conditions surrounding the EBS components. The focus of this paper is to discuss what is currently known about the NF environment, particularly those aspects whose interaction with EBS components have significant impacts on the performance of the EBS and its ability to contribute to the isolation of radioactive waste. Reference designs and design/processes assumptions are used to evaluate the expected NF environmental conditions. This report will not focus on providing parameter values but rather on the processes that influence those parameters and on the impacts of those parameters on the performance of EBS components. Where values are given, they should be viewed as typical of YM as a whole but not necessarily representative of the actual NF environment conditions that surround the EBS components. 19 refs., 6 figs

Polyurethane acrylate networks including cellulose nanocrystals: a comparison between UV and EB- curing

Science.gov (United States)

Furtak-Wrona, K.; Kozik-Ostrówka, P.; Jadwiszczak, K.; Maigret, J. E.; Aguié-Béghin, V.; Coqueret, X.

2018-01-01

A water-based polyurethane (PUR) acrylate water emulsion was selected as a radiation curable matrix for preparing nanocomposites including cellulose nanocrystals (CNC) prepared by controlled hydrolysis of Ramie fibers. Cross-linking polymerization of samples prepared in the form of films or of 1 mm-thick bars was either initiated by exposure to the 395 nm light of a high intensity LED lamp or by treatment with low energy electron beam (EB). The conversion level of acrylate functions in samples submitted to increasing radiation doses was monitored by Fourier Transform Infrared Spectroscopy (FTIR). Differential Scanning Calorimetry (DSC) and Dynamic Mechanical Analysis (DMA) were used to characterize changes in the glass transition temperature of the PUR-CNC nanocomposites as a function of acrylate conversion and of CNC content. Micromechanical testing indicates the positive effect of 1 wt% CNC on Young's modulus and on the tensile strength at break (σ) of cured nanocomposites. The presence of CNC in the PUR acrylate matrix was shown to double the σ value of the nanocomposite cured to an acrylate conversion level of 85% by treatment with a 25 kGy dose under EB, whereas no increase of σ was observed in UV-cured samples exhibiting the same acrylate conversion level. The occurrence of grafting reactions inducing covalent linkages between the polysaccharide nanofiller and the PUR acrylate matrix during the EB treatment is advanced as an explanation to account for the improvement observed in samples cured under ionizing radiation.

Tailoring the structure and properties of amorphous starch blending and EB-radiation processing

International Nuclear Information System (INIS)

Khandal, D.; Bliard, C.; Coqueret, X.; Mikus, P.Y.; Dole, P.; Baumberger, S.

2011-01-01

Complete text of publication follows. Starch can be used alone and in combination with other compounds to make biodegradable articles from renewable resources. Lignins and their derivatives are good candidates for limiting the water sensitivity of starch-based materials, but they exhibit poor compatibility in blends with polysaccharides. Electron beam (EB) processing is proposed as an efficient method for inducing covalent linkages between the two constituents. Compared to unirradiated starting materials, the surface and bulk properties of EB-irradiated starch - lignin blends submitted to EB irradiation showed an interesting reduction in hydrophilicity. Radiation induced grafting of lignin models onto starch was shown to impede long-term retrogradation, with limited loss of mechanical properties. The reactivity under radiation of model blends was examined by several analytical methods. Maldi-T of mass spectrometry allowed us to propose reasonable free radical mechanisms that account for the grafting of various benzyl and cinnamyl alcohols onto maltodextrins. The presence of cinnamyl derivatives was found not only to limit degradation, but also modify the properties of the formulations (improved hydrophobicity, mechanical properties). Size exclusion chromatography and gel fraction measurements confirmed unambiguously the attachment of UV-absorbing chromophores onto the maltodextrin main chain. The combination of the obtained results demonstrates the possibility of altering in a favourable way the tensile properties of plasticized starch by applying high energy radiation to properly formulated blends including aromatic compounds like cinnamyl alcohol.

A microstructural study of F82H-MOD. Plate, powder HIP and EB and TIG weldments

International Nuclear Information System (INIS)

Schuring, E.W.

1998-06-01

F82H is the heat identification number of a ferritic/martensitic steel. The steel has a chemical composition resulting in low activation after neutron irradiation. At ECN a microstructural study was conducted on plates of F82H (73, 15 and 25mm thick), a bar of HIPped F82H and EB and TIG welds in F82H plates. The investigation was aimed to characterise the microstructures for reference in irradiation experiments. The F82H mod. plates have a martensitic matrix with carbide precipitation on the prior austenite grain boundaries and the martensite laths. The carbide precipitation is most pronounced on the prior austenite grain boundaries. The PAG is comparable for the three plate thicknesses investigated. In two plates faint segregation bands were found with a denser carbide precipitation and 8-ferrite. Further Ta, Ti and Zr containing oxides are present. Hardness measurements show a higher overall hardness in the 25mm plate investigated compared to the 7.5 and 15mm plates. The F82H HIP bar shows a homogeneous PAG throughout the diameter. The microstructure shows a zone starting at about 1 mm below the surface with a width of 14mm, with a relatively high concentration of low precipitation density ferritic like fields, which corresponds to a zone with a 15HV5 lower hardness with respect to the rest of the bar. This zone is expected to be related to the HIP process. Further in the microstructure a circular pattern of W and Ta enriched inclusions is found, which mark the original HIP-powder grain boundaries. The EB-welds were manufactured by two manufactures and differ mostly in the heat input, resulting in differences in HAZ-width and the width of the weld cap. The F82H EB welds show comparable microstructures in the weld pool, with a martensitic microstructure free of carbides. All EB-welds contain 8-ferrite in concentrations of 0.1-1%. In the heat affected zone (HAZ), the coarse grained HAZ (CGHAZ) is free of carbide precipitation, whereas the fine grained HAZ (FGHAZ

optical properties and morphological structure of Eb-Irradiated LDPE / P P Blends

International Nuclear Information System (INIS)

Ali, Z.I.; Said, H.M.; Youssef, H.A.; Saleh, H.H.; Abdel Monem, N.M.

2004-01-01

Blending is an effective method for improving the physical and chemical properties of homopolymers. however, the problem of phase separation often in some polymer blends occurs due to incompatibility of homopolymer which impairs the expected physico- chemical properties of blends. in this study , isotactic polypropylene, (P P), was blended with low density polyethylene, (LDPE), in the presence of various ratios of polyfunctional monomer, (PFM), namely trimethylol propane trimethacrylate, (TMPTMA), as a crosslinking and/or compatibilizing agents. the electron beam irradiation of the investigated LDPE/PP blends was carried out at different irradiation doses up to 50 kGy to improve the compatibility of LDPE/PP blends. the dye affinity of disperse and basic dyes in LDPE, PP and LDPE/PP blends was investigated in terms of color strength and visible absorbance intensities. in addition, the microstructures of the investigated samples have been studied and it is considered as an indication of the compatibility of LDPE/PP blend. the results show that the unmodified and modified LDPE samples exhibit the highest values of both color strength and visible absorbance intensities compared with unmodified and modified PP samples. also the intensities of these values in the LDPE/PP blends decrease as the PP content increases in the blend . in addition, the increase of EB irradiation dose and PFM ratios leads to an increase in the values of color strength and visible absorbance intensities. moreover, the affinity of all investigated samples towards disperse dye is being more pronounced than the basic dye. the interfacial adhesion of LDPE/PP blend could be enhanced by adding crosslinking agent, (TMPTMA), and EB irradiation process with different irradiation doses. the obtained data for the microstructures of all the investigated samples support that the EB irradiation beside the incorporation of PEM into the homopolymer matrix remarkably improve the compatibility of the polymer blend

Properties of TEM standing waves with E||B

Science.gov (United States)

Zaghloul, H.; Buckmaster, H. A.

This paper summarizes the known properties of E∥B TEM standing waves and shows that for such waves (i) E and B cannot be linearly polarized, (ii) E ≠ αB where α is a constant (iii) it is impossible to find a Lorentz frame where E>B, (iv) direction of the propagation vector cannot be inferred from the fields at one point of the space, (v) their behaviour under Lorentz, parity, time-reversal and gauge transformations is proper, (vi) both Lorentz invariants E2 - B2 and E·B are nonzero, (vii) the magnetic helicity may be nonzero, (viii) the magnetic field may be force-free, and (ix) kμFμv ≠ 0. It also shows how electromagnetic waves can be classified using Lorentz invariants. Cet article résume les qualités connues des ondes stationnaires E∥B TEM et montre que pour des ondes parallèles (i) E et B ne peuvent pas être polarisées linéairement, (ii) E ≠ αB où a est une constante, (iii) il est impossible de trouver une construction de Lorentz où E>B, (iv) la direction de propagation d'un vecteur ne peut pas être déduite des opérations à un point d'intervalle, (v) leur conduite sous Lorentz, parité, temps inverse et transformations de jauge est propre, (vi) les deux invariants de Lorentz E2 - B2 et E·B sont non nulles (vii) l'hélice magnétique peut être non nulle (viii) l'opération magnétique peut être de force libre et (ix) KμFμ v ≠ 0. Ceci montre aussi comment les ondes électromagnétiques peuvent être classifiées, en employant les invariants de Lorentz.

Narvas näeb Eesti tantsuauhinna võitnud tantsulavastust / Rene Nõmmik ; intervjueerinud Tiia Linnart

Index Scriptorium Estoniae

Nõmmik, Rene, 1962-

2015-01-01

Narva kultuurimajas Rugodiv näeb Fine5 tantsuteatri lavastust "...and blue", mis võitis tänavu Eesti teatriauhinna. Etenduse koreograafideks ja lavastajateks on Tiina Ollesk ja Rene Nõmmik, keda on palutud lavastama ka Venemaale. Intervjuu Rene Nõmmikuga

Adopting a Sustainable Community of Practice Model when Developing a Service to Support Patients with Epidermolysis Bullosa (EB): A Stakeholder-Centered Approach.

Science.gov (United States)

Gowran, Rosemary Joan; Kennan, Avril; Marshall, Siobhán; Mulcahy, Irene; Ní Mhaille, Sile; Beasley, Sarah; Devlin, Mark

2015-02-01

Epidermolysis bullosa (EB) is a rare, genetic skin condition that is complicated, distressing, and painful and permeates every aspect of patients' lives. Support services are essential for meeting the primary needs of patients and families living with EB; however, provision is challenged by many complex issues. In collaboration with the patient organization DEBRA Ireland, this research conducted an in-depth analysis of Irish healthcare support services for EB, with a view to moving towards an improved and sustainable care pathway. A sustainable community of practice model (SCOP), as a core construct provided a simplified framework when studying this complex system. The research utilized mixed methods, comprising individual interviews, questionnaires, and a participatory action research workshop based on a soft systems approach. The study engaged patients, family members, service providers, and policy developers. Findings emphasized that the complexities of life with EB are more than 'skin deep'. The lived experience of stakeholders revealed many levels of emotion, both positive and heart-rending. Despite the positive efforts of specialists in this field, inadequacies to meet the primary needs of people with EB, such as bandages-fundamental for survival-were highlighted. Participants reported challenges relating to understanding patients' needs, access to consistent services within hospitals and the community, time constraints, and the strong emotions evoked by this severe and rare disease. The study identified several areas that can be targeted to bring about improvements in meeting primary needs. Education and research at public, policy, and practice levels need to be prioritized. It is imperative that citizens move beyond an awareness that EB exists and demonstrate a consciousness about the importance of advocating and enabling seamless and sustainable support services through collective action.

Recruitment of EB1, a Master Regulator of Microtubule Dynamics, to the Surface of the Theileria annulata Schizont

KAUST Repository

Woods, Kerry L.

2013-05-09

The apicomplexan parasite Theileria annulata transforms infected host cells, inducing uncontrolled proliferation and clonal expansion of the parasitized cell population. Shortly after sporozoite entry into the target cell, the surrounding host cell membrane is dissolved and an array of host cell microtubules (MTs) surrounds the parasite, which develops into the transforming schizont. The latter does not egress to invade and transform other cells. Instead, it remains tethered to host cell MTs and, during mitosis and cytokinesis, engages the cell\\'s astral and central spindle MTs to secure its distribution between the two daughter cells. The molecular mechanism by which the schizont recruits and stabilizes host cell MTs is not known. MT minus ends are mostly anchored in the MT organizing center, while the plus ends explore the cellular space, switching constantly between phases of growth and shrinkage (called dynamic instability). Assuming the plus ends of growing MTs provide the first point of contact with the parasite, we focused on the complex protein machinery associated with these structures. We now report how the schizont recruits end-binding protein 1 (EB1), a central component of the MT plus end protein interaction network and key regulator of host cell MT dynamics. Using a range of in vitro experiments, we demonstrate that T. annulata p104, a polymorphic antigen expressed on the schizont surface, functions as a genuine EB1-binding protein and can recruit EB1 in the absence of any other parasite proteins. Binding strictly depends on a consensus SxIP motif located in a highly disordered C-terminal region of p104. We further show that parasite interaction with host cell EB1 is cell cycle regulated. This is the first description of a pathogen-encoded protein to interact with EB1 via a bona-fide SxIP motif. Our findings provide important new insight into the mode of interaction between Theileria and the host cell cytoskeleton. 2013 Woods et al.

Recruitment of EB1, a master regulator of microtubule dynamics, to the surface of the Theileria annulata schizont.

Directory of Open Access Journals (Sweden)

Kerry L Woods

2013-05-01

Full Text Available The apicomplexan parasite Theileria annulata transforms infected host cells, inducing uncontrolled proliferation and clonal expansion of the parasitized cell population. Shortly after sporozoite entry into the target cell, the surrounding host cell membrane is dissolved and an array of host cell microtubules (MTs surrounds the parasite, which develops into the transforming schizont. The latter does not egress to invade and transform other cells. Instead, it remains tethered to host cell MTs and, during mitosis and cytokinesis, engages the cell's astral and central spindle MTs to secure its distribution between the two daughter cells. The molecular mechanism by which the schizont recruits and stabilizes host cell MTs is not known. MT minus ends are mostly anchored in the MT organizing center, while the plus ends explore the cellular space, switching constantly between phases of growth and shrinkage (called dynamic instability. Assuming the plus ends of growing MTs provide the first point of contact with the parasite, we focused on the complex protein machinery associated with these structures. We now report how the schizont recruits end-binding protein 1 (EB1, a central component of the MT plus end protein interaction network and key regulator of host cell MT dynamics. Using a range of in vitro experiments, we demonstrate that T. annulata p104, a polymorphic antigen expressed on the schizont surface, functions as a genuine EB1-binding protein and can recruit EB1 in the absence of any other parasite proteins. Binding strictly depends on a consensus SxIP motif located in a highly disordered C-terminal region of p104. We further show that parasite interaction with host cell EB1 is cell cycle regulated. This is the first description of a pathogen-encoded protein to interact with EB1 via a bona-fide SxIP motif. Our findings provide important new insight into the mode of interaction between Theileria and the host cell cytoskeleton.

Collection and application of by-product formed in e-b flue gas treatment process

International Nuclear Information System (INIS)

Chmielewski, A.G.; Tyminski, B.; Zakrzewska-Trznadel, G.; Tokunaga, O.; Machi, S.

1998-01-01

In the e-b process SO 2 and NO x are converted into ammonium sulphate and ammonium nitrate, which condenses from gas phase in the form of submicrone particles. These salts are a valuable fertilizer and should be removed from cleaned gas. Bag filter, ESP and wet gravel bed filter were applied for collecting of salt particles in pilot plant facilities. Up to now ESP is considered to be the best filtration method of aerosols formed after irradiation of flue gas. Collected salts after granulation may be used as a fertilizer enriching soil in nitrogen and sulphur or as a component of mixed fertilizer. Analysis of by-products from different e-b pilot plants confirms that it does not contain any harmful substances like heavy metals and fulfill all standards for commercial fertilizers. Also field experiments show that the by-products have the same properties as a commercial fertilizer

Environmental qualification design for NPP refurbishment to comply with revised licensing requirements

International Nuclear Information System (INIS)

MacBeth, M. J.; Hemmings, R. L.

2002-01-01

Recent Canadian Nuclear Regulatory decisions have imposed Environmental Qualification (EQ) requirements for twenty-four Reactor Building (RB) airlocks at the four-unit Pickering Nuclear Generating Station-B (PNGS-B) facility. This paper describes the EQ modification design work completed by CANATOM-NPM for the problematic aspects for such projects. The airlocks allow RB access while providing a containment boundary and are designed to prevent a potential breach of containment for all analysed station conditions. Each PNGS-B unit has three large equipment airlocks and three smaller personnel airlocks. The airlocks must function under postulated worst-case design basis accident(DBA) conditions for assigned mission durations. The design must ensure that accident conditions cannot spuriously initiate an un-requested door opening. CANATOM-NPM reviewed site data to specify the necessary EQ modifications required to satisfy licensing requirements while providing a correct and complete as-found record of the existing airlock installation. The design team assessed the installed airlocks configuration against environmental qualification requirements to finalize the list of necessary modifications. A comprehensive, cross-discipline review of proposed design changes was completed to identify any further changes required to satisfy the final EQ licensing goal. The design team also conducted a design review of the EQ modification installation strategy to integrate the design deliverables with the installation team requirements while attempting to minimize necessary outage time for EQ modification installations. This project was completed on schedule and within the cost limitations required by the client with comprehensive, high quality final design packages. Overall improvements were realized for OPG system drawings and the electronic documentation of design data. The EQ modifications designed by CANATOM-NPM will ensure the continued operation of the PNGS-B NPP past December 31

Functional design criteria for project W-252, phase II liquid effluent treatment and disposal. Revision 2

International Nuclear Information System (INIS)

Hatch, C.E.

1995-05-01

This document is the Functional Design Criteria for Project W-252. Project W-252 provides the scope to provide BAT/AKART (best available technology...) to 200 Liquid Effluent Phase II streams (B-Plant). This revision (Rev. 2) incorporates a major descoping of the project. The descoping was done to reflect a combination of budget cutting measures allowed by a less stringent regulatory posture toward the Phase II streams

Elemental imaging of organic matter and associated metals in ore deposits using micro PIXE and micro-EBS

Energy Technology Data Exchange (ETDEWEB)

Fuchs, S., E-mail: fuchs@geomin.eu [Department of Earth and Planetary Science, McGill University, 3450 University Street, Montreal H3A 0E8 (Canada); Przybylowicz, W.J., E-mail: przybylowicz@tlabs.ac.za [Materials Research Department, iThemba LABS, National Research Foundation, P.O. Box 722, Somerset West 7129 (South Africa); AGH University of Science and Technology, Faculty of Physics and Applied Computer Science, Al. A. Mickiewicza 30, 30-059 Krakow (Poland); Williams-Jones, A.E., E-mail: anthony.williams-jones@mcgill.ca [Department of Earth and Planetary Science, McGill University, 3450 University Street, Montreal H3A 0E8 (Canada)

2014-01-01

Micro-PIXE and micro-EBS analyses were carried out on samples from the Au–U-bearing Carbon Leader Reef of the Witwatersrand in South Africa to investigate the role of organic matter in the formation of this deposit. Micro-PIXE and Micro-EBS shows a very complex metal distribution within the bitumen nodules and their interstitial spaces. The style of the gold distribution and its association with epigenetic minerals (REE phosphates, phyllosilicates) indicates that all observed gold migrated in aqueous solution and precipitated by reduction on the surfaces of the bitumen nodules. Uraninite occurrences are confined to the bitumen nodules, which supports the argument of a uraninite paleo-placer; however the pervasive distribution of uranium also supports the argument that uraninite is derived from organo-metallic complexes. This study shows that micro-PIXE is a powerful tool to characterize metals associated with hydrocarbons. However, the organic matrix, the complexity of the obtained spectra and the small size of the minerals have significant influence on the reliability of the quantitative data. Due to highly variable amounts of heavy metals (U, Au, Pb) the obtained micro-EBS results are of questionable quality.

30 CFR 285.617 - What activities require a revision to my SAP, and when will MMS approve the revision?

Science.gov (United States)

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false What activities require a revision to my SAP, and when will MMS approve the revision? 285.617 Section 285.617 Mineral Resources MINERALS MANAGEMENT...: (1) Designed not to cause undue harm or damage to natural resources; life (including human and...

Student-initiated revision in child health.

Science.gov (United States)

Alfaham, M; Gray, O P; Davies, D P

1994-03-01

Most teaching of child health in Cardiff takes place in block attachments of 8 weeks. There is an introductory seminar of 2 days followed by a 6-week clinical attachment in a district general hospital in Wales, and then a revision period of one week designed to help students formalize and structure their basic knowledge and to clarify aspects of child health which they may have had difficulty in understanding. The revision programme has to take into account: the short time available, the small number of teaching staff, the most relevant basic knowledge and active participation by the student. This paper describes how this week has been improved through the use of student-initiated revision (SIR). The students' appraisal of this revision and in particular SIR is presented.

Structure and characteristics of EB-PVD thermal insulation layers; Struktur und Eigenschaften von EB-PVD-Waermedaemmschichten

Energy Technology Data Exchange (ETDEWEB)

Schulz, U. [Deutsche Forschungsanstalt fuer Luft- und Raumfahrt e.V. (DLR), Koeln (Germany). Inst. fuer Werkstoff-Forschung

1996-12-31

Thermal insulation layers for guide blades and rotor blades in the first two stages of a high-pressure turbines are produced by electron-beam physical vapour deposition for maximum quality. The layers have a lifetime that is longer by a factor of 2 to 10 than for plasma-sprayed layers. The following characteristics of the ceramic layer have a decisive influence on the life of the composite system: Phase composition, distribution and stability, microstructure, density, thickness, crack distribution and cohesive strength. Some selected aspects of the interdependence between production parameters, microstructure of the thermal insulation layer and service life are gone into. [Deutsch] Zur Herstellung von Waermedaemmschichten (WDS) fuer Turbinenleit- und Laufschaufeln der ersten beiden Stufen in der Hochdruckturbine wird fuer hoechste Ansprueche an die Schichtqualitaet das EB-PDV-Verfahren (electron-beam physical vapour deposition) eingesetzt. Die Lebensdauer dieser Schichten ist um den Faktor 2 bis 10 besser als beim Plasmaspritzen. Bei der keramischen Waermedaemmschicht selbst beeinflussen folgende Eigenschaften die Lebensdauer des Gesamtschichtsystems nachhaltig: Phasenzusammensetzung, -verteilung und -stabilitaet, Mikrogefuege, Dichte, Dicke, Rissverteilung und kohaesive Festigkeit. Auf einige ausgewaehlt Aspekte des Zusammenhangs zwischen Herstellungsparametern, Mikrostruktur der Waermedaemmschicht und Lebensdauer wird kurz eingegangen. (orig.)

Practical and safe implementation of disposal with prefabricated EBS modules

International Nuclear Information System (INIS)

Kawamura, Hideki; McKinley, Ian G.; Neall, Fiona B.

2008-01-01

The use of prefabricated EBS modules ('PEMs') to minimise the problems involved with handling compacted bentonite and ensuring that it is emplaced to established quality levels has been investigated in various national programmes for disposal of both HLW and SF. To date, however, this has tended to be decoupled from studies of related operational aspects such as assessing / minimising the consequences of use of concrete for support structures, ensuring ease of tele-operated reversal of waste packages during emplacement (e.g. in the event of operational disturbances) / retrieval at a later time, logistical optimisation (especially for programmes with large waste inventories) and cost minimisation. It is clear that specific aspects of operational safety and practicality can be considerably enhanced if designs are modified with a focus on them. It is trickier to provide optimised solutions, which simultaneously address all these critical points. Nevertheless, with a bit of lateral thinking, it appears possible to devise options that may not only ease the operational phase, but may also actually improve post-closure safety case robustness - although improved, more realistic performance assessment codes and databases will be needed to demonstrate this rigorously. To illustrate this approach, an example will be presented based of disposal of vitrified HLW in a fractured hard rock; the general principles involved are, however, also applicable to other higher activity wastes and other host rocks. Key aspects of the design are: Optimisation of PEM design for both short-term and long-term performance; Development of a rail emplacement system which eases remote handled emplacement / recovery; Large diameter, lined emplacement tunnels to ensure operational robustness; Use of multi-package overpacks (e.g. 6 HLW containers in each PEM) and short tunnels to ease emplacement logistics; and Backfilling with a non-swelling sacrificial pH buffer (eases handling and improves

EB treatment of wastewater and progress of on-going project in China

International Nuclear Information System (INIS)

Wang Zhiguang

2006-01-01

Electron beam processing has been widely used in China in the fields of radiation crosslinking cables and wires, heat shrinkable material, foam materials, irradiated latex and polymers, sterilization, removal SOx and NOx of flue gas, chemical industry, industrial CT, electron instrument, and so on. However, EB treatment of wastewater is mostly under study in laboratory. The manufacture of electron accelerators has also become a comparatively independent industry in China. (author)

Late effects of atomic bomb radiation on human immune responses, (10); Results on studies of immune responses to EB-virus

Energy Technology Data Exchange (ETDEWEB)

Kusunoki, Yoichiro; Kyoizumi, Seishi; Ozaki, Kyoko; Saito, Mayumi; Cologne, J.B.; Akiyama, Mitoshi (Radiation Effects Research Foundation, Hiroshima (Japan))

1992-12-01

Anti-Epstein-Barr (EV) virus antibody titers were measured in age- and sex-matched three groups of each 124 A-bomb survivors who had exposed to <0.01 Gy, 0.01-1 Gy, or >1 Gy. These serum samples showed positive antibodies against viral capsid antigens (VCA). Antibody titers to anti-VCA-IgM or anti-EA-IgG were significantly higher in the groups of 0.01-1 Gy and >1 Gy than in the group of <0.01 Gy, reflecting decreased immune response ability for EV virus. When precursor frequency of cytotoxic cells against autologous EB virus LCL was determined in 68 other A-bomb survivors, no definitive influence of A-bombing was observed. However, serological study revealed that there was inverse correlation between precursor frequency and anti-EA-IgG antibody titer. These findings suggest that the immune response ability for EB virus may have been damaged and that biological reactivity of EB virus may occur frequently in A-bomb survivors. (N.K.).

Expedited technology demonstration project (Revised mixed waste management facility project) Project baseline revision 4.0 and FY98 plan

International Nuclear Information System (INIS)

Adamson, M. G.

1997-01-01

The re-baseline of the Expedited Technology Demonstration Project (Revised Mixed Waste Facility Project) is designated as Project Baseline Revision 4.0. The last approved baseline was identified as Project Baseline Revision 3.0 and was issued in October 1996. Project Baseline Revision 4.0 does not depart from the formal DOE guidance followed by, and contained in, Revision 3.0. This revised baseline document describes the MSO and Final Forms testing activities that will occur during FY98, the final year of the ETD Project. The cost estimate for work during FY98 continues to be $2.OM as published in Revision 3.0. However, the funds will be all CENRTC rather than the OPEX/CENTRC split previously anticipated. LLNL has waived overhead charges on ETD Project CENRTC funds since the beginning of project activities. By requesting the $2.OM as all CENTRC a more aggressive approach to staffing and testing can be taken. Due to a cost under- run condition during FY97 procurements were made and work was accomplished, with the knowledge of DOE, in the Feed Preparation and Final Forms areas that were not in the scope of Revision 3.0. Feed preparation activities for FY98 have been expanded to include the drum opening station/enclosure previously deleted

Fast-track revision knee arthroplasty

DEFF Research Database (Denmark)

Husted, Henrik; Otte, Niels Kristian Stahl; Kristensen, Billy B

2011-01-01

Abstract Background and purpose Fast-track surgery has reduced the length of hospital stay (LOS), morbidity, and convalescence in primary hip and knee arthroplasty (TKA). We assessed whether patients undergoing revision TKA for non-septic indications might also benefit from fast-track surgery....... Methods 29 patients were operated with 30 revision arthroplasties. Median age was 67 (34-84) years. All patients followed a standardized fast-track set-up designed for primary TKA. We determined the outcome regarding LOS, morbidity, mortality, and satisfaction. Results Median LOS was 2 (1-4) days...

Analysis of postulated events for the revised ALMR/PRISM design

International Nuclear Information System (INIS)

Slovik, G.C.; Tuyle, G.J. Van

1992-01-01

The Nuclear Regulatory Commission (NRC) is continuing a pre-application review of the 471 MWt, liquid metal reactor, PRISM, by General Electric, with Brookhaven National Laboratory providing technical support. The revised design has been evaluated, using the SSC code, for an unscrammed loss of heat sink (ULOHS), an unscrammed loss of flow (ULOF) with and without the Gas Expansion Modules (GEMs), and a 40 cents unscrammed transient overpower (UTOP) event. The feedback effects for U-27Pu-10Zr metal fuel were modeled in SSC. The ULOHS accident was determined to be a benign event for the design, with the reactor power transitioning down to a decay heat level within 500s. The power during the postulated ULOF events, with the GEMs functioning, transitioned to decay heat levels without fuel damage, and included a 300K margin to sodium saturation. The case without the GEMs had only a 160K margin to sodium saturation and higher fuel temperatures. In addition, the clad was predicted to quickly pass through the eutectic phase (between fuel and clad), and some clad wastage would result. The 40 cents UTOP was predicted to raise the power to 1.8 rated, which later stabilized near 1.2 times full power. SSC predicted some localized fuel melting for the event, but the significance of this localized damage has not yet been determined. If necessary, the vendor has options to reduce the maximum reactivity insertion below 40 cents

Analysis of postulated events for the revised ALMR/PRISM design

International Nuclear Information System (INIS)

Slovik, G.C.; Van Tuyle, G.J.

1991-01-01

The Nuclear Regulatory Commission (NRC) is continuing a pre-application review of the 471 MWt, Liquid Metal Reactor, PRISM by General Electric, with Brookhaven National Laboratory providing technical support. The revised design has been evaluated, using the SSC code, for an unscrammed loss of heat sink (ULOHS), an unscrammed loss of flow (ULOF) with and without the Gas Expansion Modules (GEMs), and a 40 cents unscrammed transient overpower (UTOP) event. The feedback effects for U-27Pu-10Zr metal fuel were modeled in SSC. The ULOHS accident was determined to be a benign event for the design, with the reactor power transitioning down to a decay heat level within 500s. The power during the postulated ULOF events, with the GEMs functioning, transitioned to decay heat levels without fuel damage, and included a 300K margin to sodium saturation. The case without the GEMs had only a 160K margin to sodium saturation and higher fuel temperatures. In addition, the clad was predicted to quickly pass through the eutectic phase (between fuel and clad), and some clad wastage would result. The 40 cents UTOP was predicted to raise the power to 1.8 rated, which later stabilized near 1.2 times full power. SSC predicted some localized fuel melting for the event, but the significance of this localized damage has not yet been determined. If necessary, the vendor has options to reduce the maximum reactivity insertion below 40 cents

A revised design and implementation of the ATLAS Log Service package

Science.gov (United States)

Murillo Garcia, Raul; Lehamnn Miotto, Giovanna; ATLAS TDAQ Collaboration

2011-12-01

This paper presents a revised design and implementation of the Log Service for the ATLAS Trigger and Data Acquisition (TDAQ) framework at CERN. A previous version of this utility was rarely used for various reasons, herein explained. The lessons learned set the grounds and motivation for a new redesign. The Log Service consists of the Logger, the entity that collects logs and stores them in an Oracle database; a set of user utilities to access and maintain the database; and a Java based tool, known as the Log Manager, which provides a compact and intuitive interface for browsing the log messages based on a user defined search criteria. The outline of these software components are explained, including various optimization techniques deployed in order to handle the large volume of entries expected to be stored in the database. Finally, a performance study has been conducted to prove the validity and behavior of the Log Service.

A revised design and implementation of the ATLAS Log Service package

CERN Document Server

Murillo García, R; The ATLAS collaboration

2010-01-01

This paper presents a revised design and implementation of the Log Service for the ATLAS Trigger and Data Acquisition (TDAQ) framework at CERN. A previous version of this utility was rarely used for various reasons, herein explained. The lessons learned set the grounds and motivation for a new redesign. The Log Service consists of the Logger, the entity that collects logs and stores them in an Oracle database; a set of user utilities to access and maintain the database; and a Java based tool, known as the Log Manager, which provides a compact and intuitive interface for browsing the log messages based on a user defined search criteria. The outline of these software components are explained, including various optimization techniques deployed in order to handle the large volume of entries expected to be stored in the database. Finally, a performance study has been conducted to prove the validity and behavior of the Log Service.

Wechsler Adult Intelligence Scale-Revised Block Design broken configuration errors in nonpenetrating traumatic brain injury.

Science.gov (United States)

Wilde, M C; Boake, C; Sherer, M

2000-01-01

Final broken configuration errors on the Wechsler Adult Intelligence Scale-Revised (WAIS-R; Wechsler, 1981) Block Design subtest were examined in 50 moderate and severe nonpenetrating traumatically brain injured adults. Patients were divided into left (n = 15) and right hemisphere (n = 19) groups based on a history of unilateral craniotomy for treatment of an intracranial lesion and were compared to a group with diffuse or negative brain CT scan findings and no history of neurosurgery (n = 16). The percentage of final broken configuration errors was related to injury severity, Benton Visual Form Discrimination Test (VFD; Benton, Hamsher, Varney, & Spreen, 1983) total score and the number of VFD rotation and peripheral errors. The percentage of final broken configuration errors was higher in the patients with right craniotomies than in the left or no craniotomy groups, which did not differ. Broken configuration errors did not occur more frequently on designs without an embedded grid pattern. Right craniotomy patients did not show a greater percentage of broken configuration errors on nongrid designs as compared to grid designs.

Updated Design Standards and Guidance from the What Works Clearinghouse: Regression Discontinuity Designs and Cluster Designs

Science.gov (United States)

Cole, Russell; Deke, John; Seftor, Neil

2016-01-01

The What Works Clearinghouse (WWC) maintains design standards to identify rigorous, internally valid education research. As education researchers advance new methodologies, the WWC must revise its standards to include an assessment of the new designs. Recently, the WWC has revised standards for two emerging study designs: regression discontinuity…

Safety, Pharmacokinetics and Dosimetry of a Long-Acting Radiolabeled Somatostatin Analogue 177Lu-DOTA-EB-TATE in Patients with Advanced Metastatic Neuroendocrine Tumors.

Science.gov (United States)

Zhang, Jingjing; Wang, Hao; Jacobson Weiss, Orit; Cheng, Yuejuan; Niu, Gang; Li, Fang; Bai, Chunmei; Zhu, Zhaohui; Chen, Xiaoyuan

2018-04-13

Radiolabeled somatostatin analogue therapy has become an established treatment method for patients with well to moderately differentiated unresectable or metastatic neuroendocrine tumors (NETs). The most frequently used somatostatin analogues in clinical practice are octreotide and octreotate. However, both peptides showed suboptimal retention within tumors. The aim of this first-in-human study is to explore the safety and dosimetry of a long-acting radiolabeled somatostatin analogue, lutetium-177-1, 4, 7, 10-tetra-azacyclododecane-1, 4, 7, 10-tetraacetic acid-Evans blue-octreotate ( 177 Lu-DOTA-EB-TATE). Methods: Eight patients (6 males and 2 females; age range, 27-61 y) with advanced metastatic neuroendocrine tumors were recruited. Five patients received a single dose 0.35-0.70 GBq (9.5-18.9 mCi) of 177 Lu-DOTA-EB-TATE and underwent serial whole body planar and single-photon emission computed tomography-computed tomography (SPECT-CT) scans at 2, 24, 72, 120 and 168 h after injection. The other 3 patients received intravenous injection of 0.28-0.41 GBq (7.5-11.1 mCi) of 177 Lu-DOTATATE for the same imaging acquisition procedures at 1, 3, 4, 24 and 72 h after injection. The dosimetry was calculated using the OLINDA/EXM 1.1 software. Results: Administration of 177 Lu-DOTA-EB-TATE was well tolerated, with no adverse symptoms being noticed or reported in any of the patients. Compared with 177 Lu-DOTATATE, 177 Lu-DOTA-EB-TATE showed extended circulation in the blood and achieved 7.9-fold increase of tumor dose delivery. The total body effective doses were 0.205 ± 0.161 mSv/MBq for 177 Lu-DOTA-EB-TATE and 0.174 ± 0.072 mSv/MBq for 177 Lu-DOTATATE. Significant dose delivery increases to the kidneys and bone marrow were also observed in patients receiving 177 Lu-DOTA-EB-TATE than those receiving 177 Lu-DOTATATE (3.2 and 18.2-fold, respectively). Conclusion: By introducing an albumin binding moiety, 177 Lu-DOTA-EB-TATE showed remarkably higher uptake and retention in NET

Welding of cold worked austenitic steels - comparison of TIG, EB and laser processes

International Nuclear Information System (INIS)

Richard, A.; Prunele, D. de; Castilan, F.

1993-01-01

Effect of welding on cold worked components is a local falling of their properties. Modifications induced by such an operation depend on the thermal cycle and consequently on the welding process. An experimental study aim of which is to compare respective effects of different welding processes (TIG, EB, laser) has been realized. This publication presents results related to 316L and 316Ti steels. (author). 2 refs., 7 figs., 1 tab

Comparing contemporary revision burden among hip and knee joint replacement registries

Directory of Open Access Journals (Sweden)

Brian J. McGrory, MD, MS

2016-06-01

Conclusions: Revision burden has gradually decreased for hip replacements and has remained relatively constant for knee replacements both for the last 4 years and compared to historic controls. Knee revision burden was lower than hip revision burden for each period examined. Revision burden is one measure that may be helpful in following the effect of changes in surgical technique and implant design over time in registry populations and may be a helpful way to compare overall results between registries.

pKWmEB: integration of Kruskal-Wallis test with empirical Bayes under polygenic background control for multi-locus genome-wide association study.

Science.gov (United States)

Ren, Wen-Long; Wen, Yang-Jun; Dunwell, Jim M; Zhang, Yuan-Ming

2018-03-01

Although nonparametric methods in genome-wide association studies (GWAS) are robust in quantitative trait nucleotide (QTN) detection, the absence of polygenic background control in single-marker association in genome-wide scans results in a high false positive rate. To overcome this issue, we proposed an integrated nonparametric method for multi-locus GWAS. First, a new model transformation was used to whiten the covariance matrix of polygenic matrix K and environmental noise. Using the transferred model, Kruskal-Wallis test along with least angle regression was then used to select all the markers that were potentially associated with the trait. Finally, all the selected markers were placed into multi-locus model, these effects were estimated by empirical Bayes, and all the nonzero effects were further identified by a likelihood ratio test for true QTN detection. This method, named pKWmEB, was validated by a series of Monte Carlo simulation studies. As a result, pKWmEB effectively controlled false positive rate, although a less stringent significance criterion was adopted. More importantly, pKWmEB retained the high power of Kruskal-Wallis test, and provided QTN effect estimates. To further validate pKWmEB, we re-analyzed four flowering time related traits in Arabidopsis thaliana, and detected some previously reported genes that were not identified by the other methods.

The Revised Space Environment Models in CREME-MC: A Replacement for CREME96

Science.gov (United States)

Adams, James H., Jr.; Barghouty, Abdulnasser F.; Mendenhall, Marcus H.; Reed, Robert A.; Sierawski, Brian; Watts, John W.; Weller, Robert A.

2010-01-01

The CREME96 model has been available on the WWW for more than 10 years now. While principally for the estimation of radiation effects on spacecraft electronics, it contains space radiation environment models that have been used for instrument design calculations, estimation of instrumental background, estimation of radiation hazards and many other purposes. Because of the evolution of electronic part design we have found it necessary to revise CREME96, creating CREME-MC. As part of this revision, we are revising and extending the environmental models in CREME96. This talk will describe the revised radiation environment models that are being made available in CREME-MC

Preliminary waste form characteristics report Version 1.0. Revision 1

International Nuclear Information System (INIS)

Stout, R.B.; Leider, H.R.

1991-01-01

This report focuses on radioactive waste form characteristics that will be used to design a waste package and an engineered barrier system (EBS) for a suitable repository as part of the Yucca Mountain Project. The term waste form refers to irradiated reactor fuel, other high-level waste (HLW) in various physical forms, and other radioactive materials (other than HLW) which are received for emplacement in a geologic repository. Any encapsulating of stabilizing matrix is also referred to as a waste form

76 FR 59927 - Treatment of Aliens Whose Employment Creation Immigrant (EB-5) Petitions Were Approved After...

Science.gov (United States)

2011-09-28

...-0029] RIN 1615-AA90 Treatment of Aliens Whose Employment Creation Immigrant (EB-5) Petitions Were... qualifying aliens whose employment-creation immigrant petitions were approved by the former Immigration and...-273 Provisions C. Summary of the Adjudications Required by Public Law 107-273 III. Aliens Eligible To...

Revising Translations

DEFF Research Database (Denmark)

Rasmussen, Kirsten Wølch; Schjoldager, Anne

2011-01-01

The paper explains the theoretical background and findings of an empirical study of revision policies, using Denmark as a case in point. After an overview of important definitions, types and parameters, the paper explains the methods and data gathered from a questionnaire survey and an interview...... survey. Results clearly show that most translation companies regard both unilingual and comparative revisions as essential components of professional quality assurance. Data indicate that revision is rarely fully comparative, as the preferred procedure seems to be a unilingual revision followed by a more...... or less comparative rereading. Though questionnaire data seem to indicate that translation companies use linguistic correctness and presentation as the only revision parameters, interview data reveal that textual and communicative aspects are also considered. Generally speaking, revision is not carried...

GTSE1 is a microtubule plus-end tracking protein that regulates EB1-dependent cell migration.

Directory of Open Access Journals (Sweden)

Massimilano Scolz

Full Text Available The regulation of cell migration is a highly complex process that is often compromised when cancer cells become metastatic. The microtubule cytoskeleton is necessary for cell migration, but how microtubules and microtubule-associated proteins regulate multiple pathways promoting cell migration remains unclear. Microtubule plus-end binding proteins (+TIPs are emerging as important players in many cellular functions, including cell migration. Here we identify a +TIP, GTSE1, that promotes cell migration. GTSE1 accumulates at growing microtubule plus ends through interaction with the EB1+TIP. The EB1-dependent +TIP activity of GTSE1 is required for cell migration, as well as for microtubule-dependent disassembly of focal adhesions. GTSE1 protein levels determine the migratory capacity of both nontransformed and breast cancer cell lines. In breast cancers, increased GTSE1 expression correlates with invasive potential, tumor stage, and time to distant metastasis, suggesting that misregulation of GTSE1 expression could be associated with increased invasive potential.

Evaluation of interfacial mechanical properties under shear loading in EB-PVD TBCs by the pushout method

Energy Technology Data Exchange (ETDEWEB)

Kim, Sang-Seok [Research Center for Advanced Science and Technology, University of Tokyo, Tokyo 153-8904 (Japan); Liu Yufu [Research Center for Advanced Science and Technology, University of Tokyo, Tokyo 153-8904 (Japan); Kagawa, Yutaka [Research Center for Advanced Science and Technology, University of Tokyo, Tokyo 153-8904 (Japan)]. E-mail: kagawa@iis.u-tokyo.ac.jp

2007-06-15

A new simple pushout technique for evaluation of interfacial shear mechanical properties in thermal barrier coatings has been developed. The technique is similar to the pushout test of fiber-reinforced ceramics, except for the specimen shape and support method. The technique has been applied to evaluation of interfacial delamination toughness, {gamma} {sub i}, of the electron beam physical vapor deposition (EB-PVD) ZrO{sub 2} thermal barrier coating (TBC) system. The change of {gamma} {sub i} in the EB-PVD system with thermal exposure is measured and discussed in terms of microstructural change and delamination crack path. The measured delamination toughness varied from {gamma} {sub i} = 10 to 115 J/m{sup 2}. The delamination path and TGO growth were found to be closely related. The delamination toughness significantly decreases due to the formation and growth of a spinel phase in the TGO layer. The relation between delamination toughness and delamination behavior is discussed.

76 FR 61288 - Treatment of Aliens Whose Employment Creation Immigrant (EB-5) Petitions Were Approved After...

Science.gov (United States)

2011-10-04

... DEPARTMENT OF HOMELAND SECURITY 8 CFR Parts 216 and 245 [CIS No. 2484-09; Docket No. USCIS-2009-0029] RIN 1615-AA90 Treatment of Aliens Whose Employment Creation Immigrant (EB-5) Petitions Were... corrects an inadvertent error contained in the proposed rule titled Treatment of Aliens Whose Employment...

Studies on curing effect of phosphite monomer by EB radiation in the air

International Nuclear Information System (INIS)

Xiao, B.; Zhou, Y.; Li, S.; Luo, M.; Wang, X.; Zhao, P.

2000-01-01

A new type phosphite active monomer was synthesized. The resisting oxygen inhibition effect of this monomer and the effects of irradiation dose and concentration of phosphite active monomer on curing were studied. At the same time, curing results were analysed, through gel content and IR spectrum. The excellent resisting oxygen inhibition result of this phosphite active monomer was shown by experiments. EB radiation curing in the air was successfully carried out by the phosphite active monomer. (author)

A mutation of the fission yeast EB1 overcomes negative regulation by phosphorylation and stabilizes microtubules

International Nuclear Information System (INIS)

Iimori, Makoto; Ozaki, Kanako; Chikashige, Yuji; Habu, Toshiyuki; Hiraoka, Yasushi; Maki, Takahisa; Hayashi, Ikuko; Obuse, Chikashi; Matsumoto, Tomohiro

2012-01-01

Mal3 is a fission yeast homolog of EB1, a plus-end tracking protein (+ TIP). We have generated a mutation (89R) replacing glutamine with arginine in the calponin homology (CH) domain of Mal3. Analysis of the 89R mutant in vitro has revealed that the mutation confers a higher affinity to microtubules and enhances the intrinsic activity to promote the microtubule-assembly. The mutant Mal3 is no longer a + TIP, but binds strongly the microtubule lattice. Live cell imaging has revealed that while the wild type Mal3 proteins dissociate from the tip of the growing microtubules before the onset of shrinkage, the mutant Mal3 proteins persist on microtubules and reduces a rate of shrinkage after a longer pausing period. Consequently, the mutant Mal3 proteins cause abnormal elongation of microtubules composing the spindle and aster. Mal3 is phosphorylated at a cluster of serine/threonine residues in the linker connecting the CH and EB1-like C-terminal motif domains. The phosphorylation occurs in a microtubule-dependent manner and reduces the affinity of Mal3 to microtubules. We propose that because the 89R mutation is resistant to the effect of phosphorylation, it can associate persistently with microtubules and confers a stronger stability of microtubules likely by reinforcing the cylindrical structure. -- Highlights: ► We characterize a mutation (mal3-89R) in fission yeast homolog of EB1. ► The mutation enhances the activity to assemble microtubules. ► Mal3 is phosphorylated in a microtubule-dependent manner. ► The phosphorylation negatively regulates the Mal3 activity.

A mutation of the fission yeast EB1 overcomes negative regulation by phosphorylation and stabilizes microtubules

Energy Technology Data Exchange (ETDEWEB)

Iimori, Makoto; Ozaki, Kanako [Graduate School of Biostudies, Kyoto University, Kitashirakawa-Oiwake cho, Sakyo ku, Kyoto, 606-8502 (Japan); Chikashige, Yuji [Kobe Advanced ICT Research Center, National Institute of Information and Communications Technology, Kobe, 651-2492 (Japan); Habu, Toshiyuki [Graduate School of Biostudies, Kyoto University, Kitashirakawa-Oiwake cho, Sakyo ku, Kyoto, 606-8502 (Japan); Radiation Biology Center, Kyoto University, Yoshida-Konoe cho, Sakyo ku, Kyoto, 606-8501 (Japan); Hiraoka, Yasushi [Kobe Advanced ICT Research Center, National Institute of Information and Communications Technology, Kobe, 651-2492 (Japan); Graduate School of Frontier Biosciences, Osaka University, 1-3 Yamadaoka, Suita, 565-0871 (Japan); Maki, Takahisa; Hayashi, Ikuko [Graduate School of Nanobioscience, Yokohama City University, Tsurumi, Yokohama, 230-0045 (Japan); Obuse, Chikashi [Graduate School of Life Science, Hokkaido University, Sapporo 001-0021 (Japan); Matsumoto, Tomohiro, E-mail: tmatsumo@house.rbc.kyoto-u.ac.jp [Graduate School of Biostudies, Kyoto University, Kitashirakawa-Oiwake cho, Sakyo ku, Kyoto, 606-8502 (Japan); Radiation Biology Center, Kyoto University, Yoshida-Konoe cho, Sakyo ku, Kyoto, 606-8501 (Japan)

2012-02-01

Mal3 is a fission yeast homolog of EB1, a plus-end tracking protein (+ TIP). We have generated a mutation (89R) replacing glutamine with arginine in the calponin homology (CH) domain of Mal3. Analysis of the 89R mutant in vitro has revealed that the mutation confers a higher affinity to microtubules and enhances the intrinsic activity to promote the microtubule-assembly. The mutant Mal3 is no longer a + TIP, but binds strongly the microtubule lattice. Live cell imaging has revealed that while the wild type Mal3 proteins dissociate from the tip of the growing microtubules before the onset of shrinkage, the mutant Mal3 proteins persist on microtubules and reduces a rate of shrinkage after a longer pausing period. Consequently, the mutant Mal3 proteins cause abnormal elongation of microtubules composing the spindle and aster. Mal3 is phosphorylated at a cluster of serine/threonine residues in the linker connecting the CH and EB1-like C-terminal motif domains. The phosphorylation occurs in a microtubule-dependent manner and reduces the affinity of Mal3 to microtubules. We propose that because the 89R mutation is resistant to the effect of phosphorylation, it can associate persistently with microtubules and confers a stronger stability of microtubules likely by reinforcing the cylindrical structure. -- Highlights: Black-Right-Pointing-Pointer We characterize a mutation (mal3-89R) in fission yeast homolog of EB1. Black-Right-Pointing-Pointer The mutation enhances the activity to assemble microtubules. Black-Right-Pointing-Pointer Mal3 is phosphorylated in a microtubule-dependent manner. Black-Right-Pointing-Pointer The phosphorylation negatively regulates the Mal3 activity.

Development of Ground Test System For RKX-200EB

Science.gov (United States)

Yudhi Irwanto, Herma

2018-04-01

After being postponed for seven years, the development of RKX-200EB now restarts by initiating a ground test, preceding the real flight test. The series of the development starts from simulation test using the real vehicle and its components, focusing on a flight sequence test using hardware in the loop simulation. The result of the simulation shows that the autonomous control system in development is able to control the X tail fin vehicle, since take off using booster, separating booster-sustainer, making flight maneuver using sustainer with average cruise speed of 1000 km/h, and doing bank to maneuver up to ±40 deg heading to the target. The simulation result also shows that the presence of sustainer in vehicle control can expand the distance range by 162% (12.6 km) from its ballistic range using only a booster.

[Heinike Heinsoo. Mā ja pūd lēväd, meid eb lē] / Fedor Rozhanskiy

Index Scriptorium Estoniae

Rozhanskiy, Fedor

2013-01-01

Arvustus: Heinike Heinsoo. Mā ja pūd lēväd, meid eb lē : the subject and the predicate in Votic. Tallinn : Teaduste Akadeemia Kirjastus, 2010. (Linguistica Uralica. Supplementary series ; vol. 4)

MAJOR REPOSITORY DESIGN ISSUES

International Nuclear Information System (INIS)

JACK N. BAILEY, DWAYNE CHESTNUT, JAMES COMPTON AND RICHARD D. SNELL

1997-01-01

The Yucca Mountain Project is focused on producing a four-part viability assessment in late FY98. Its four components (design, performance assessment, cost estimate, and licensing development plan) must be consistent. As a tool to compare design and performance assessment options, a series of repository pictures were developed for the sequential time phases of a repository. The boundaries of the time phases correspond to evolution in the engineered barrier system (EBS)

Revision total hip arthoplasty: factors associated with re-revision surgery.

Science.gov (United States)

Khatod, Monti; Cafri, Guy; Inacio, Maria C S; Schepps, Alan L; Paxton, Elizabeth W; Bini, Stefano A

2015-03-04

The survivorship of implants after revision total hip arthroplasty and risk factors associated with re-revision are not well defined. We evaluated the re-revision rate with use of the institutional total joint replacement registry. The purpose of this study was to determine patient, implant, and surgeon factors associated with re-revision total hip arthroplasty. A retrospective cohort study was conducted. The total joint replacement registry was used to identify patients who had undergone revision total hip arthroplasty for aseptic reasons from April 1, 2001, to December 31, 2010. The end point of interest was re-revision total hip arthroplasty. Risk factors evaluated for re-revision total hip arthroplasty included: patient risk factors (age, sex, body mass index, race, and general health status), implant risk factors (fixation type, bearing surface, femoral head size, and component replacement), and surgeon risk factors (volume and experience). A multivariable Cox proportional hazards model was used. Six hundred and twenty-nine revision total hip arthroplasties with sixty-three (10%) re-revisions were evaluated. The mean cohort age (and standard deviation) was 57.0 ± 12.4 years, the mean body mass index (and standard deviation) was 29.5 ± 6.1 kg/m(2), and most of the patients were women (64.5%) and white (81.9%) and had an American Society of Anesthesiologists score of associated with the risk of re-revision. For every ten-year increase in patient age, the hazard ratio for re-revision decreases by a factor of 0.72 (95% confidence interval, 0.58 to 0.90). For every five revision surgical procedures performed by a surgeon, the risk of revision decreases by a factor of 0.93 (95% confidence interval, 0.86 to 0.99). At the time of revision, a new or retained cemented femoral implant or all-cemented hip implant increases the risk of revision by a factor of 3.19 (95% confidence interval, 1.22 to 8.38) relative to a retained or new uncemented hip implant. A ceramic on a

A new design of automatic vertical drilling tool

Directory of Open Access Journals (Sweden)

Yanfeng Ma

2015-09-01

Full Text Available In order to effectively improve penetration rates and enhance wellbore quality for vertical wells, a new Automatic Vertical Drilling Tool (AVDT based on Eccentric Braced Structure (EBS is designed. Applying operating principle of rotary steering drilling, AVDT adds offset gravity block automatic induction inclination mechanism. When hole straightening happens, tools take essentric moment to be produced by gravity of offset gravity lock to control the bearing of guide force, so that well straightening is achieved. The normal tool's size of the AVDT is designed as 215.9 mm，other major components' sizes are worked out by the result of theoretical analysis, including the offset angle of EBS. This paper aims to introduce the structure, operating principle, theoretical analysis and describe the key components' parameters setting of the AVDT.

Carlsbad Area Office strategic plan, March 1995. Revision 1

International Nuclear Information System (INIS)

1995-03-01

This edition of the Carlsbad Area Office Strategic Plan captures the US Department of Energy's (DOE's) new focus, and supersedes the edition issued previously (DOE, 1993a). This revision reflects: a revised strategy designed to demonstrate compliance with environmental regulations earlier than the previous course of action; and a focus on establishment of standardized transuranic waste characterization and acceptance criteria for disposal facilities

Inquiry, A Project of the Wisconsin Bar Foundation. Vols. 1 and 2, Revised.

Science.gov (United States)

Scheurich, G. Michael, Ed.

This new, revised edition of the Inquiry instructional materials is designed for use in teaching high school students about the U. S. laws and legal systems. The revised outlines, designed for instructors who have had legal training, are less technical and more informal, include new concepts and many current relevant topics, and de-emphasize…

76 FR 75562 - Notice of a Change in Status of an Extended Benefit (EB) Period for Pennsylvania

Science.gov (United States)

2011-12-02

... Extended Benefit (EB) Period for Pennsylvania AGENCY: Employment and Training Administration, Labor. ACTION... Pennsylvania. The following changes have occurred since the publication of the last notice regarding the State... three month average, seasonally- adjusted total unemployment rate for Pennsylvania rose to exceed the 8...

Applied socio-hydrology using volunteer geographic information (VGI) to integrate ecosystem-based adaptation (EbA) and disaster risk reduction (DRR)

Science.gov (United States)

Mendiondo, Eduardo; Taffarello, Denise; Mohor, Guilherme; Guzmán, Diego; Câmara de Freitas, Clarissa; Fava, Maria Clara; Restrepo, Camilo; Abreu, Fernando; Batalini, Marina; Lago, Cesar; Abe, Narumi; Rosa, Altair

2017-04-01

Socio-hydrology proposes to understand coupled human-water systems by conceptualizing its components to be dynamically connected by bi-directional feedbacks. For practical purposes, especially in developing countries of South America, socio-hydrology does integrate practical, empirical and theoretical fundamentals from citizens' knowledge and culture. This contribution shows South American examples of how volunteer geographic information (VGI) can help socio-hydrology to integrate emerging aspects with heavy feedbacks, exploding uncertainties and relevant scales of socio-hydrological scales. Here we select examples at different scales of using VGI to link aspects of ecosystem-based adaptation (EbA) and disaster risk reduction (DRR). On the one hand, we show some learning cases of EbA/VGI linked to socio-hydrology also related with water valuation, both monetary and non-monetary, under scenarios of changing conditions of land-use and land cover changes of strategic water supply systems in subtropical biomes. This example brings a bridge of VGI and EbA towards Disaster Risk Reduction (DRR) through water topics of securitization, insurance, smart cities and sustainable urban drainage systems (SUDS). Thus, on the other hand, we also depict how VGI support applied elements for socio-hydrology on South American urban areas, capable of policy actions for DRR through SUDS at human-impacted biomes under extremes of droughts, floods and pollution. We here recommend yardsticks of learning conditions from these real examples of using VGI's knowledge and culture biases for a more resilient socio-hydrology, in order to create opportunities for theoretical, conceptual and applied nature of EbA and DRR with viable alliances from IAHS/Panta Rhei with UN/Sendai/DRR Framework and UN/Sustainable Development Goals. From these examples, however, seem plausible co-evolutionary dynamics with stakeholders if local-scale constraints, from sociopolitical nature, institutions' policies and

Standard practice for prediction of the long-term behavior of materials, including waste forms, used in engineered barrier systems (EBS) for geological disposal of high-level radioactive waste

CERN Document Server

American Society for Testing and Materials. Philadelphia

2007-01-01

1.1 This practice describes test methods and data analyses used to develop models for the prediction of the long-term behavior of materials, such as engineered barrier system (EBS) materials and waste forms, used in the geologic disposal of spent nuclear fuel (SNF) and other high-level nuclear waste in a geologic repository. The alteration behavior of waste form and EBS materials is important because it affects the retention of radionuclides by the disposal system. The waste form and EBS materials provide a barrier to release either directly (as in the case of waste forms in which the radionuclides are initially immobilized), or indirectly (as in the case of containment materials that restrict the ingress of groundwater or the egress of radionuclides that are released as the waste forms and EBS materials degrade). 1.1.1 Steps involved in making such predictions include problem definition, testing, modeling, and model confirmation. 1.1.2 The predictions are based on models derived from theoretical considerat...

The Energy Balance Study: The Design and Baseline Results for a Longitudinal Study of Energy Balance

Science.gov (United States)

Hand, Gregory A.; Shook, Robin P.; Paluch, Amanda E.; Baruth, Meghan; Crowley, E. Patrick; Jaggers, Jason R.; Prasad, Vivek K.; Hurley, Thomas G.; Hebert, James R.; O'Connor, Daniel P.; Archer, Edward; Burgess, Stephanie; Blair, Steven N.

2013-01-01

Purpose: The Energy Balance Study (EBS) was a comprehensive study designed to determine over a period of 12 months the associations of caloric intake and energy expenditure on changes in body weight and composition in a population of healthy men and women. Method: EBS recruited men and women aged 21 to 35 years with a body mass index between 20…

Evaluation of Tc-99M labeled ethylene diamine tetra acetic acid biotin monomer (EB1) as an inflammation imaging agent

International Nuclear Information System (INIS)

Imran, M.B.; Qaiser, I.; Jehangir, M.; Irfan, J.

2004-01-01

Objective:This study was aimed at the evaluation of EB1 as an inflammation-imaging agent in animal models after ascertaining its normal biodistribution. Methods: Kit was formulated by adding SnC12 as reducing agent in EB 1 compound. EDTA was used as chelating agent. Buffer was added to lower the pH of solution to 5. Freeze dried kits were prepared for later use in experiments. Kits were reconstituted with 0.5 ml of fresh eluate of 99m-TcO4 containing total activity of about 370 MBq. Radiochemical quality control was checked by conventional strip method using double solvent technique.Biodistribution was assessed in 15 Sprague Dawley rats. An injection of 10 MBq was given in tail vein in each animal. Animals were killed at pre-specified time intervals; organs were separated, weighed and counted. Counts recovered were corrected for decay. Inflammation models were prepared by injecting turpentine oil in the thigh muscles of 14 rabbits. In one rabbit inflammation was not induced and was used as control for EB 1. In 3 of inflammation models plain 99m-TcO4 was injected (control II). In another group of 3 animals 99m-TC-EDTA was injected (control II). In the last group of 8 animals 99m-TcO4-EB 1 was injected (experimental gp). Animals were serially imaged under Seimens' E-Cam gamma camera for the distribution of activity in different organs and at the site of inflammation. Results: Kit labeling efficiency was 90.5 + 2.5% with 2.5 + 0.8% free activity and 7 + 1.1% hydrolyzed form. Animal study on rats showed that pharmaceutical is mainly excreted by kidneys (51.57 + 9.2% at 15 minutes and 81.73 + 7.9% at 4 hours). Uptake in liver was 7.52 + 2.2% at 15 minutes that decreased to 2.3 + 0.5% at 4 hours. Activity in intestine increased from 5.48 + 2.9% to 7.05 + 1.6% at 15 minutes to 4 hours. Activity in background (=blood) decreased from 0.13% (at 15 minutes) to 0.04% at 4 hrs. In bones EB1 uptake decreased from 0.68% to 0.15% at 15 minutes to 4 hours. In inflammation models

23 CFR 636.409 - Can offerors revise their proposals during communications?

Science.gov (United States)

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Can offerors revise their proposals during communications? 636.409 Section 636.409 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS DESIGN-BUILD CONTRACTING Exchanges § 636.409 Can offerors revise their...

Short-term survival of the trabecular metal cup is similar to that of standard cups used in acetabular revision surgery.

Science.gov (United States)

Mohaddes, Maziar; Rolfson, Ola; Kärrholm, Johan

2015-02-01

The use of trabecular metal (TM) cups in revision surgery has increased worldwide during the last decade. Since the introduction of the TM cup in Sweden in 2006, this design has gradually replaced other uncemented designs used in Sweden. According to data from the Swedish Hip Arthroplasty Register (SHAR) in 2012, one-third of all uncemented first-time cup revisions were performed using a TM cup. We compared the risk of reoperation and re-revision for TM cups and the 2 other most frequently used cup designs in acetabular revisions reported to the SHAR. The hypothesis was that the performance of TM cups is as good as that of established designs in the short term. The study population consisted of 2,384 patients who underwent 2,460 revisions during the period 2006 through 2012. The most commonly used cup designs were the press-fit porous-coated cup (n = 870), the trabecular metal cup (n = 805), and the cemented all-polyethylene cup (n = 785). 54% of the patients were female, and the median age at index revision was 72 (19-95) years. Reoperation was defined as a second surgical intervention, and re-revision-meaning exchange or removal of the cup-was used as endpoint. The mean follow-up time was 3.3 (0-7) years. There were 215 reoperations, 132 of which were re-revisions. The unadjusted and adjusted risk of reoperation or re-revision was not significantly different for the TM cup and the other 2 cup designs. Our data support continued use of TM cups in acetabular revisions. Further follow-up is necessary to determine whether trabecular metal cups can reduce the re-revision rate in the long term, compared to the less costly porous press-fit and cemented designs.

Comparison between Duncan and Chang’s EB Model and the Generalized Plasticity Model in the Analysis of a High Earth-Rockfill Dam

Directory of Open Access Journals (Sweden)

Weixin Dong

2013-01-01

Full Text Available Nonlinear elastic model and elastoplastic model are two main kinds of constitutive models of soil, which are widely used in the numerical analyses of soil structure. In this study, Duncan and Chang's EB model and the generalized plasticity model proposed by Pastor, Zienkiewicz, and Chan was discussed and applied to describe the stress-strain relationship of rockfill materials. The two models were validated using the results of triaxial shear tests under different confining pressures. The comparisons between the fittings of models and test data showed that the modified generalized plasticity model is capable of simulating the mechanical behaviours of rockfill materials. The modified generalized plasticity model was implemented into a finite element code to carry out static analyses of a high earth-rockfill dam in China. Nonlinear elastic analyses were also performed with Duncan and Chang's EB model in the same program framework. The comparisons of FEM results and in situ monitoring data showed that the modified PZ-III model can give a better description of deformation of the earth-rockfill dam than Duncan and Chang’s EB model.

Residual stress measurement of EB-welded plates with contour method. Part 2: FEM analysis of contour profiles

International Nuclear Information System (INIS)

Romppanen, A.-J.; Immonen, E.

2013-12-01

The residual stresses formed as a result of Electronic Beam welding (EB-welding) in copper are investigated by Posiva. In the present study, residual stresses of EB-welded copper plates were studied with contour method. In the method eleven copper plates (X436 - X440 and X453 - X458) were cut in half with wire electric discharge machining (EDM) after which the deformation due to stress relaxation was measured with coordinate measurement system. The measured data was then used as boundary displacement data for the FEM analyses, in which the corresponding residual stresses were calculated. Before giving the corresponding displacement boundary conditions to the FE models, the deformation data was processed and smoothed appropriately. The residual stress levels of the copper plates were found to be around 40 - 55 MPa at maximum. This corresponds to other reported residual stress measurements and current state of knowledge with this material in Posiva. (orig.)

The addition of calcitriol or its synthetic analog EB1089 to lapatinib and neratinib treatment inhibits cell growth and promotes apoptosis in breast cancer cells.

Science.gov (United States)

Segovia-Mendoza, Mariana; Díaz, Lorenza; Prado-Garcia, Heriberto; Reginato, Mauricio J; Larrea, Fernando; García-Becerra, Rocío

2017-01-01

In breast cancer the use of small molecule inhibitors of tyrosine kinase activity of the ERBB family members improves survival thus represents a valuable therapeutic strategy. The addition of calcitriol, the most active metabolite of vitamin D, or some of its analogs, to conventional anticancer drugs, including tyrosine kinase inhibitors (TKIs), has shown an increased effect on the inhibition of cancer cell growth. In this work, we have evaluated the effects and the mechanism of action of the combination of calcitriol or its analog EB1089 with lapatinib or neratinib on EGFR and/or HER2 positive breast cancer cell lines. Lapatinib, neratinib, calcitriol and EB1089 inhibited breast cancer cell proliferation in a concentration-dependent manner. Addition of calcitriol or EB1089 to TKIs treatment induced more effective inhibiting effect on cell growth and AKT and MAPK phosphorylation than all compounds alone. The combined treatments incremented also the expression of active caspase 3 and induced cell death in two and three-dimensional cell culture and significantly inhibited anchorage-independent colony formation. Our results suggest that the addition of calcitriol or its analog EB1089 to conventional targeted therapies, including lapatinib or neratinib might be of benefit to patients with breast cancer, particularly those with an EGFR and/or HER2 positive phenotype.

Discussion on some issues for HAF003 revision

International Nuclear Information System (INIS)

Huang Chaoyun, Wang Xiaotao; Duan Hongwei; Tian Feng

2013-01-01

This paper describes some key issues which should be considered during the revision of safety code Quality Assurance for Nuclear Power Plant (HAF003), based on the comparatively analysis and research on the quality assurance practice for nuclear power. It covers about 24 issues including management responsibilities, independent assessment, design control and procurement control etc. and is expected to provide some reference and proposal for HAF003 revision activities organized by National Nuclear Safety Agency (NNSA). (authors)

EPRI PWR primary water chemistry guidelines revision

International Nuclear Information System (INIS)

McElrath, Joel; Fruzzetti, Keith

2014-01-01

EPRI periodically updates the PWR Primary Water Chemistry Guidelines as new information becomes available and as required by NEI 97-06 (Steam Generator Program Guidelines) and NEI 03-08 (Guideline for the Management of Materials Issues). The last revision of the PWR water chemistry guidelines identified an optimum primary water chemistry program based on then-current understanding of research and field information. This new revision provides further details with regard to primary water stress corrosion cracking (PWSCC), fuel integrity, and shutdown dose rates. A committee of industry experts, including utility specialists, nuclear steam supply system (NSSS) and fuel vendor representatives, Institute of Nuclear Power Operations (INPO) representatives, consultants, and EPRI staff collaborated in reviewing the available data on primary water chemistry, reactor water coolant system materials issues, fuel integrity and performance issues, and radiation dose rate issues. From the data, the committee updated the water chemistry guidelines that all PWR nuclear plants should adopt. The committee revised guidance with regard to optimization to reflect industry experience gained since the publication of Revision 6. Among the changes, the technical information regarding the impact of zinc injection on PWSCC initiation and dose rate reduction has been updated to reflect the current level of knowledge within the industry. Similarly, industry experience with elevated lithium concentrations with regard to fuel performance and radiation dose rates has been updated to reflect data collected to date. Recognizing that each nuclear plant owner has a unique set of design, operating, and corporate concerns, the guidelines committee has retained a method for plant-specific optimization. Revision 7 of the Pressurized Water Reactor Primary Water Chemistry Guidelines provides guidance for PWR primary systems of all manufacture and design. The guidelines continue to emphasize plant

Revision Total Hip Arthoplasty: Factors Associated with Re-Revision Surgery

OpenAIRE

Khatod, M; Cafri, G; Inacio, MCS; Schepps, AL; Paxton, EW; Bini, SA

2015-01-01

The survivorship of implants after revision total hip arthroplasty and risk factors associated with re-revision are not well defined. We evaluated the re-revision rate with use of the institutional total joint replacement registry. The purpose of this study was to determine patient, implant, and surgeon factors associated with re-revision total hip arthroplasty.A retrospective cohort study was conducted. The total joint replacement registry was used to identify patients who had undergone revi...

Revision of nuclear power plants safety systems' routine testing assigned periodicity during the design extension period

International Nuclear Information System (INIS)

Skalozubov, V.I.; Kozlov, Yi.L.; Chulkyin, O.O.

2017-01-01

When nuclear power plants safety systems thermal equipment operation extending, a necessary requirement shall rely on revising the scheduled equipment tests frequency to optimize those tests schedule taking into account the equipment remained lifespan. On the one hand, there exists a need for tests frequency increase to detect ''hidden'' failures, and on the another, frequent tests cause a premature wear of the equipment. Proposed is an original method for optimizing the frequency of NPPs safety systems thermal engineering equipment testing. Essential in the proposed method is the optimization criterion chosen: index of security system failure probability non-exceedance during the beyond-design operating period as referred to the failure probability expected considering the equipment residual resource during the design operating period. The developed method implementation when applied to NPPs safety systems operated beyond the design service life at nuclear power plants with WWER-1000 series reactors, allowed to establish that the optimal tests frequency makes half the designed one when the equipment service life is extended by five years and three times less that the designed frequency when subject lifespan extended by 10 years.

Development of radiation curable surface coating based on soybean oil. part II: Evaluation of the prepared acrylated resin as surface coatings by using EB or UV sources for radiation curing applications

International Nuclear Information System (INIS)

Ibrahim, M.S.; Said, H.M.; Moussa, I.M.

2005-01-01

In recent years, there has been a growing trend in using vegetable oils as raw materials in acylation production that can be cured by UV/EB systems. The acrylated resin formulates by using individually different functional acrylate monomers were prepared and cured by EB or UV sources. The characterization properties of the cured films were investigated in terms of pendulum hardness, bending, impact, gloss, adhesion and chemical tests. Other formulations were prepared by mixing a constant ratio of different functional acrylate monomers and exposed to UV or EB irradiation. The results showed that the hardness of cured films were increased by increasing the functionality of monomers with excellent adhesion for all formulations but at expense of other properties involving bending and impact tests. Therefore, it can be deduce that the hardness of the curing surface coating by using EB was found to be nearly twice the hardness of the curing surface coating by using UV irradiation. Also, the best formulations which have given good chemical and mechanical properties are (mono-di) functional acrylate monomer resin under EB and (mono-tri) functional acrylate monomer resin under UV irradiation

Revised

DEFF Research Database (Denmark)

Johannsen, Vivian Kvist; Nord-Larsen, Thomas; Riis-Nielsen, Torben

This report is a revised analysis of the Danish data on CO2 emissions from forest, afforestation and deforestation for the period 1990 - 2008 and a prognosis for the period until 2020. Revision have included measurements from 2009 in the estimations. The report is funded by the Ministry of Climate...

Selective application of revised source terms to operating nuclear power plants

International Nuclear Information System (INIS)

Moon, Joo Hyun; Song, Jae Hyuk; Lee, Young Wook; Ko, Hyun Seok; Kang, Chang Sun

2001-01-01

More than 30 years later since 1962 when TID-14844 was promulgated, there has been big change of the US NRC's regulatory position in using accident source terms for radiological assessment following a design basis accident (DBA). To replace the instantaneous source terms of TID-14844, the time-dependent source terms of NUREG-1465 was published in 1995. In the meantime, the radiological acceptance criteria for reactor site evaluation in 10 CFR Part 100 were also revised. In particular, the concept of total effective dose equivalent has been incorporated in accordance with the radiation protection standards set forth in revised 10 CFR Part 20. Subsequently, the publication of Regulatory Guide 1.183 and the revision of Standard Review Plan 15.0.1 followed in 2000, which provided the licensee of operating nuclear power reactor with the acceptable guidance of applying the revised source term. The guidance allowed the holder of an operating license issued prior to January 10, 1997 to voluntarily revise the accident source terms used in the radiological consequence analyses of DBA. Regarding to its type of application, there suggested full and selective applications, Whether it is full or selective, based upon the scope and nature of associated plant modifications being proposed, the actual application of the revised source terms to an operating plant is expected to give a large impact on its facility design basis. Considering scope and cost of the analyses required for licensing, selective application is seemed to be more appealing to an licensee of the operating plant rather than full application. In this paper, hence, the selective application methodology is reviewed and is actally applied to the assessment of offsite radiological consequence following a LOCA at Ulchin Unit 3 and 4, in order to identify and analyze the potential impacts due to application of revised source terms and to assess the considerations taken in each application prior to its actual

The status of UV/EB curable product in North America: 1998-1999

International Nuclear Information System (INIS)

Lawson, K.

1999-01-01

This author has previously reported survey results showing that the use of UV/EB materials has grown at a compound rate of about 10% per annum over the last decade. Together, with about 130 members of RadTech International North America, representing 90 organizations, we have updated and assessed the growth and activities of the industry. The panelists represent a cross section of end users, raw material and equipment suppliers, as well as formulators and consultants. Using a modified Delphi process with five separate survey rounds, a reasonable assessment was made of the advantages, disadvantages, growth rate and growth opportunities of this exciting technology

Relation of Thermal Conductivity with Process Induced Anisotropic Void Systems in EB-PVD PYSZ Thermal Barrier Coatings

Energy Technology Data Exchange (ETDEWEB)

Renteria, A. Flores; Saruhan-Brings, B.; Ilavsky, J.

2008-03-03

Thermal barrier coatings (TBCs) deposited by Electron-beam physical deposition (EB-PVD) protect the turbine blades situated at the high pressure sector of the aircraft and stationary turbines. It is an important task to uphold low thermal conductivity in TBCs during long-term service at elevated temperatures. One of the most promising methods to fulfil this task is to optimize the properties of PYSZ-based TBC by tailoring its microstructure. Thermal conductivity of the EB-PVD produced PYSZ TBCs is influenced mainly by the size, shape, orientation and volume of the various types of porosity present in the coatings. These pores can be classified as open (inter-columnar and between feather arms gaps) and closed (intra-columnar pores). Since such pores are located within the three-dimensionally deposited columns and enclose large differences in their sizes, shapes, distribution and anisotropy, the accessibility for their characterization is very complex and requires the use of sophisticated methods. In this work, three different EB-PVD TBC microstructures were manufactured by varying the process parameters, yielding various characteristics of their pores. The corresponding thermal conductivities in as-coated state and after ageing at 11000C/1h and 100h were measured via Laser Flash Analysis Method (LFA). The pore characteristics and their individual effect on the thermal conductivity are analysed by USAXS which is supported by subsequent modelling and LFA methods, respectively. Evident differences in the thermal conductivity values of each microstructure were found in as-coated and aged conditions. In summary, broader columns introduce higher values in thermal conductivity. In general, thermal conductivity increases after ageing for all three investigated microstructures, although those with initial smaller pore surface area show smaller changes.

Relation of thermal conductivity with process induced anisotropic void system in EB-PVD PYSZ thermal barrier coatings.

Energy Technology Data Exchange (ETDEWEB)

Renteria, A. F.; Saruhan, B.; Ilavsky, J.; German Aerospace Center

2007-01-01

Thermal barrier coatings (TBCs) deposited by Electron-beam physical deposition (EB-PVD) protect the turbine blades situated at the high pressure sector of the aircraft and stationary turbines. It is an important task to uphold low thermal conductivity in TBCs during long-term service at elevated temperatures. One of the most promising methods to fulfil this task is to optimize the properties of PYSZ-based ,TBC by tailoring its microstructure. Thermal conductivity of the EB-PVD produced PYSZ TBCs is influenced mainly by the size, shape, orientation and volume of the various types of porosity present in the coatings. These pores can be classified as open (inter-columnar and between feather arms gaps) and closed (intra-columnar pores). Since such pores are located within the three-dimensionally deposited columns and enclose large differences in their sizes, shapes, distribution and anisotropy, the accessibility for their characterization is very complex and requires the use of sophisticated methods. In this work, three different EB-PVD TBC microstructures were manufactured by varying the process parameters, yielding various characteristics of their pores. The corresponding thermal conductivities in as-coated state and after ageing at 1100C/1h and 100h were measured via Laser Flash Analysis Method (LFA). The pore characteristics and their individual effect on the thermal conductivity are analysed by USAXS which is supported by subsequent modelling and LFA methods, respectively. Evident differences in the thermal conductivity values of each microstructure were found in as-coated and aged conditions. In summary, broader columns introduce higher values in thermal conductivity. In general, thermal conductivity increases after ageing for all three investigated microstructures, although those with initial smaller pore surface area show smaller changes.

Design of modern experiments(revised version)

International Nuclear Information System (INIS)

Park, Sung Hweon

1984-03-01

This book mentions design of modern experiments. It includes conception of design of experiments, a key statistics theory, one way design of experiment, two-way layout without repetition and with repetition, multi layout and analysis of enumerated data, partition, correlation and regression analysis, latin squares, factorial design, design of experiment by table of orthogonal arrays I, II, incomplete block design, design of response surface, design of compound experiment, Evop and steepest ascent or descent method and design of experiment of taguchi.

Scrimer: designing primers from transcriptome data

Czech Academy of Sciences Publication Activity Database

Mořkovský, Libor; Pačes, Jan; Rídl, Jakub; Reifová, R.

2015-01-01

Roč. 15, č. 6 (2015), s. 1415-1420 ISSN 1755-098X R&D Projects: GA MŠk EE2.3.20.0303 Institutional support: RVO:68081766 ; RVO:68378050 Keywords : next-generation sequencing * primer design * SNaPshot * SNP genotyping * transcriptome Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 5.298, year: 2015

Recent geodynamic and geomorphological analyses of the Diendorf–Čebín Tectonic Zone, Czech Republic

Czech Academy of Sciences Publication Activity Database

Roštínský, Pavel; Pospíšil, L.; Švábenský, O.

2013-01-01

Roč. 599, 25. červen 2013 (2013), s. 45-66 ISSN 0040-1951 Grant - others:GA MŠk(CZ) ED2.1.00/03.0097 Institutional support: RVO:68145535 Keywords : Diendorf – Čebín Tectonic Zone * Bohemian Massif * recent movement Subject RIV: DE - Earth Magnetism, Geodesy, Geography Impact factor: 2.866, year: 2013 http://dx.doi.org/10.1016/j.tecto.2013.04.008

Review on the seismic safety of JRR-3 according to the revised regulatory code on seismic design for nuclear reactors

Energy Technology Data Exchange (ETDEWEB)

Kobayashi, Tetsuya; Araki, Masaaki; Ohba, Toshinobu; Torii, Yoshiya [Japan Atomic Energy Agency, Tokai, Ibaraki (Japan); Takeuchi, Masaki [Nuclear Safety Commission (Japan)

2012-03-15

JRR-3(Japan Research Reactor No.3) with the thermal power of 20MW is a light water moderated and cooled, swimming pool type research reactor. JRR-3 has been operated without major troubles. This paper presents about review on the seismic safety of JRR-3 according to the revised regulatory code on seismic design for nuclear reactors. In addition, some topics concerning damages in JRR-3 due to the Great East Japan Earthquake are presented. (author)

Evidence for the characterization of heavy-ion reactions by the ratio E/B

International Nuclear Information System (INIS)

Mathews, G.J.; Wozniak, G.J.; Schmitt, R.P.; Moretto, L.G.

1977-01-01

The connection between the characteristic features of reactions involving very heavy target-projectile combinations (e.g. 86 Kr + 197 Au) and lighter systems (e.g. 40 Ar + sup(nat)Ag) is discussed. Evidence for an impirical scaling law based upon the ratio E/B (center-of-mass kinetic energy to Coulomb barrier) is presented. This scaling is justified in terms of semiquantitative arguments whereby the different charge and angular distribution patterns from light and heavy target-projectile combinations are correlated with different lifetime regimes for the 'intermediate complex' as it diffuses along the mass-asymmetry coordinate. (orig.) [de

78 FR 59982 - Revisions to Radiation Protection

Science.gov (United States)

2013-09-30

... NUCLEAR REGULATORY COMMISSION [NRC-2012-0268] Revisions to Radiation Protection AGENCY: Nuclear..., ``Radiation Sources,'' Section 12.3 -12.4, ``Radiation Protection Design Features,'' and Section 12.5, ``Operational Radiation Protection Program.'' DATES: The effective date of this Standard Review Plan update is...

Extractable proteins from electron beam (EB) irradiated natural rubber (NR) latex

International Nuclear Information System (INIS)

Feroza Akhtar; Fumio Yoshii; Keizo Makuuchi

1996-01-01

The protein assay of natural rubber latex (NRL) vulcanized by low energy electron beam (EB, 300 keV, 30 mA) has been carried out using Bicinchoninic acid (BCA) reagent. Extractable protein in irradiated latex film was determined by measuring the absorption of colored solution at 562 nm using UV spectrometer. The effect of various radiation doses on the extractable protein content of NRL was investigated. It was ,found that the quantities of extractable protein increases with radiation dose. When compared with ,gamma-ray irradiated samples the same trend was observed. Electron beam irradiated latex films are leached in 1% (ammonia water for various lengths of time. From the results it was established that within 2 hours of leaching in ammonia water most of the extractable protein (96%) were removed from rubber film

Design Smart Games with requirements, generate them with a Click, and revise them with a GUIs

Directory of Open Access Journals (Sweden)

Vincenza COFINI

2012-12-01

Full Text Available TERENCE is an FP7 ICT European project that is developing an adaptive learning system for supporting poor comprehenders and their educators. Its learning material are books of stories and games. The games are specialised into smart games, which stimulate inference-making for story comprehension, and relaxing games, which stimulate visual perception and not story comprehension. The paper focuses on smart games. It first describes the TERENCE system architecture, thus delves into the design of smart games starting from the requirements and their automated generation, by highlighting the role of the reasoning module therein. Finally, it outlines the manual revision of the generated smart games, and ends with short conclusions about the planned improvements on the automated generation process.

The revised classification of eukaryotes

Czech Academy of Sciences Publication Activity Database

Adl, S.; Simpson, A. G. B.; Lane, C. E.; Lukeš, Julius; Bass, D.; Bowser, S. S.; Brown, M W.; Burki, F.; Dunthorn, M.; Hampl, V.; Heiss, A.; Hoppenrath, M.; Lara, E.; Gall, L. L.; Lynn, D. H.; McManus, H.; Mitchell, E. A. D.; Mozley-Stanridge, S. E.; Parfrey, L. W.; Pawlowski, J.; Rueckert, S.; Shadwick, L.; Schoch, C.L.; Smirnov, A.; Spiegel, F. W.

2012-01-01

Roč. 59, č. 5 (2012), s. 429-514 ISSN 1066-5234 Institutional support: RVO:60077344 Keywords : Algae * amoebae * biodiversity * ciliates * flagellates * fungi * parasites * protozoa * systematics * taxonomy Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.162, year: 2012 http://onlinelibrary.wiley.com/doi/10.1111/j.1550-7408.2012.00644.x/pdf

Waste receiving and processing facility module 1, detailed design report

International Nuclear Information System (INIS)

1993-10-01

WRAP 1 baseline documents which guided the technical development of the Title design included: (a) A/E Statement of Work (SOW) Revision 4C: This DOE-RL contractual document specified the workscope, deliverables, schedule, method of performance and reference criteria for the Title design preparation. (b) Functional Design Criteria (FDC) Revision 1: This DOE-RL technical criteria document specified the overall operational criteria for the facility. The document was a Revision 0 at the beginning of the design and advanced to Revision 1 during the tenure of the Title design. (c) Supplemental Design Requirements Document (SDRD) Revision 3: This baseline criteria document prepared by WHC for DOE-RL augments the FDC by providing further definition of the process, operational safety, and facility requirements to the A/E for guidance in preparing the design. The document was at a very preliminary stage at the onset of Title design and was revised in concert with the results of the engineering studies that were performed to resolve the numerous technical issues that the project faced when Title I was initiated, as well as, by requirements established during the course of the Title II design

The design study of an ultra-high power EB/X-ray conversion facility

Energy Technology Data Exchange (ETDEWEB)

He, Zi-Feng, E-mail: hezifeng@sinap.ac.cn; Li, Deming; Huang, Jian-Ming; Yang, Yong-Jin; Zhu, Xi-Kai; Zhang, Yu-Tian

2014-10-15

Highlights: • We describe a 100 kW electron beam to X-rays conversion system. • We give an idea to improve the conversion efficiency and lifetime of the target. • We describe the design and thermal characteristics of the X-ray converter. - Abstract: X-ray conversion is a frequent need for irradiating the products that cannot be processed by electron beams, duo to their limited penetration capacity in materials, in radiation sterilization of disposable healthcare products and food irradiation. In this paper, we report the design of a conversion facility with a 5-MeV/120-kW electron accelerator, regarding the considerations on selection of the target materials and target structure, design of the electron beam transport line and approaches to improve the conversion efficiency and lifetime.

Skalní řícení na hradě Jestřebí a jeho příčiny

Czech Academy of Sciences Publication Activity Database

Adamovič, Jiří; Kaňková, H.

2010-01-01

Roč. 19, - (2010), s. 137-162 ISSN 1211-9172 R&D Projects: GA AV ČR IAA300130806 Institutional research plan: CEZ:AV0Z30130516 Keywords : rockfall * Bohemian Cretaceous Basin * sandstone * Jestřebí Castle (Czech Republic) Subject RIV: DB - Geology ; Mineralogy

Preliminary hazards analysis of thermal scrap stabilization system. Revision 1

International Nuclear Information System (INIS)

Lewis, W.S.

1994-01-01

This preliminary analysis examined the HA-21I glovebox and its supporting systems for potential process hazards. Upon further analysis, the thermal stabilization system has been installed in gloveboxes HC-21A and HC-21C. The use of HC-21C and HC-21A simplified the initial safety analysis. In addition, these gloveboxes were cleaner and required less modification for operation than glovebox HA-21I. While this document refers to glovebox HA-21I for the hazards analysis performed, glovebox HC-21C is sufficiently similar that the following analysis is also valid for HC-21C. This hazards analysis document is being re-released as revision 1 to include the updated flowsheet document (Appendix C) and the updated design basis (Appendix D). The revised Process Flow Schematic has also been included (Appendix E). This Current revision incorporates the recommendations provided from the original hazards analysis as well. The System Design Description (SDD) has also been appended (Appendix H) to document the bases for Safety Classification of thermal stabilization equipment

Evidence-Based Design and Research-Informed Design: What's the Difference? Conceptual Definitions and Comparative Analysis.

Science.gov (United States)

Peavey, Erin; Vander Wyst, Kiley B

2017-10-01

This article provides critical examination and comparison of the conceptual meaning and underlying assumptions of the concepts evidence-based design (EBD) and research-informed design (RID) in order to facilitate practical use and theoretical development. In recent years, EBD has experienced broad adoption, yet it has been simultaneously critiqued for rigidity and misapplication. Many practitioners are gravitating to the term RID to describe their method of integrating knowledge into the design process. However, the term RID lacks a clear definition and the blurring of terms has the potential to weaken advances made integrating research into practice. Concept analysis methods from Walker and Avant were used to define the concepts for comparison. Conceptual definitions, process descriptions, examples (i.e., model cases), and methods of evaluation are offered for EBD and RID. Although EBD and RID share similarities in meaning, the two terms are distinct. When comparing evidence based (EB) and research informed, EB is a broad base of information types (evidence) that are narrowly applied (based), while the latter references a narrow slice of information (research) that is broadly applied (informed) to create an end product of design. Much of the confusion between the use of the concepts EBD and RID arises out of differing perspectives between the way practitioners and academics understand the underlying terms. The authors hope this article serves to generate thoughtful dialogue, which is essential to the development of a discipline, and look forward to the contribution of the readership.

Evolution of photo-stimulated luminescence of EB-PVD/(Ni, Pt)Al thermal barrier coatings

International Nuclear Information System (INIS)

Wen Mei; Jordan, Eric H.; Gell, Maurice

2005-01-01

Experiments are described which were designed to assess the suitability of photo-stimulated luminescence piezo-spectroscopy (PLPS) measurements as a basis for non-destructive inspection (NDI) and determination of life remaining of thermal barrier coatings (TBCs). Thermal cyclic tests were conducted on 7 wt.% Y 2 O 3 stabilized ZrO 2 (YSZ) electron beam physical vapor deposited (EB-PVD)/(Ni, Pt)Al/CMSX-4 TBCs at two temperatures 1151 and 1121 deg. C. The evolution of PLPS spectral characteristics (peak frequency shift, peak width and area ratio of peaks) was studied as a function of thermal cycles. It was observed that the average thermally grown oxide (TGO) stress and its standard deviation, and the area ratio of peaks show systematic change with thermal cycling, indicating that these characteristics can be used for NDI and determination of life remaining. The average TGO stress increases initially and then decreases monotonically with thermal cycling. The rate of change in the stress can be related to specimen life: the shallower the slope, the higher the life. The peak area ratio also decreases monotonically with cycling. The average TGO stress changes in a systematic manner versus remaining life fraction independent of temperature. Remaining life predictions were made based on average stress versus life fraction, which resulted in life assessments within ±13% of actual values excluding one specimen with abnormal behavior

Revising and editing for translators

CERN Document Server

Mossop, Brian

2014-01-01

Revising and Editing for Translators provides guidance and learning materials for translation students learning to edit texts written by others, and professional translators wishing to improve their self-revision ability or learning to revise the work of others. Editing is understood as making corrections and improvements to texts, with particular attention to tailoring them to the given readership. Revising is this same task applied to draft translations. The linguistic work of editors and revisers is related to the professional situations in which they work. Mossop offers in-depth coverage of a wide range of topics, including copyediting, style editing, structural editing, checking for consistency, revising procedures and principles, and translation quality assessment. This third edition provides extended coverage of computer aids for revisers, and of the different degrees of revision suited to different texts. The inclusion of suggested activities and exercises, numerous real-world examples, a proposed gra...

Development of the Wechsler Memory Scale--Revised.

Science.gov (United States)

Herman, David O.; Young, Laura

A study involving a sample of people selected to represent the nonimpaired American population, aged 16 to 74 years, was undertaken to determine the effectiveness of the Wechsler Memory Scale--Revised. The scale's subtests were designed to assess memory of personal and general knowledge, logical memory, verbal paired association, figural memory,…

Loosening After Acetabular Revision

DEFF Research Database (Denmark)

Beckmann, Nicholas A.; Weiss, Stefan; Klotz, Matthias C.M.

2014-01-01

The best method of revision acetabular arthroplasty remains unclear. Consequently, we reviewed the literature on the treatment of revision acetabular arthroplasty using revision rings (1541 cases; mean follow-up (FU) 5.7 years) and Trabecular Metal, or TM, implants (1959 cases; mean FU 3.7 years...

INDIRECT WRITTEN CORRECTIVE FEEDBACK, REVISION, AND LEARNING

Directory of Open Access Journals (Sweden)

Fatemeh Poorebrahim

2017-01-01

Full Text Available Corrective feedback, the necessity of providing it, and how it should be provided has been one of the hot topics in the area of ELT. Amid continuing controversies over whether providing feedback helps L2 learners improve their writing accuracy, many research studies have been undertaken to compare the relative effectiveness of different types of feedback. However, the difference between two types of indirect corrective feedback, namely indication and indication plus location, have not been properly examined yet. Motivated to narrow this gap, this study is designed to compare two groups of Iranian learners, each revising their papers based on one of the aforementioned options. For data analysis, a series of independent samples t tests were employed. The results revealed that the difference between the two groups in their reduction of errors from the original draft to the revision of each task followed a growing trend and became significant. Nonetheless, the difference in accuracy of new pieces of writing fell short of significance. Finally, it was found that error reduction in revision stage cannot be considered as learning. The results of the study, discussed in relation to that of others, implicate that the purpose for which feedback is provided is essential in determining the type of feedback; more explicit feedback is better for revising purposes while more implicit feedback is good for learning purposes.

Single-photon sensitive fast ebCMOS camera system for multiple-target tracking of single fluorophores: application to nano-biophotonics

Science.gov (United States)

Cajgfinger, Thomas; Chabanat, Eric; Dominjon, Agnes; Doan, Quang T.; Guerin, Cyrille; Houles, Julien; Barbier, Remi

2011-03-01

Nano-biophotonics applications will benefit from new fluorescent microscopy methods based essentially on super-resolution techniques (beyond the diffraction limit) on large biological structures (membranes) with fast frame rate (1000 Hz). This trend tends to push the photon detectors to the single-photon counting regime and the camera acquisition system to real time dynamic multiple-target tracing. The LUSIPHER prototype presented in this paper aims to give a different approach than those of Electron Multiplied CCD (EMCCD) technology and try to answer to the stringent demands of the new nano-biophotonics imaging techniques. The electron bombarded CMOS (ebCMOS) device has the potential to respond to this challenge, thanks to the linear gain of the accelerating high voltage of the photo-cathode, to the possible ultra fast frame rate of CMOS sensors and to the single-photon sensitivity. We produced a camera system based on a 640 kPixels ebCMOS with its acquisition system. The proof of concept for single-photon based tracking for multiple single-emitters is the main result of this paper.

Structural Properties of EB-Welded AlSi10Mg Thin-Walled Pressure Vessels Produced by AM-SLM Technology

Science.gov (United States)

Nahmany, Moshe; Stern, Adin; Aghion, Eli; Frage, Nachum

2017-10-01

Additive manufacturing of metals by selective laser melting (AM-SLM) is hampered by significant limitations in product size due to the limited dimensions of printing trays. Electron beam welding (EBW) is a well-established process that results in relatively minor metallurgical modifications in workpieces due to the ability of EBW to pass high-density energy to the related substance. The present study aims to evaluate structural properties of EB-welded AlSi10Mg thin-walled pressure vessels produced from components prepared by SLM technology. Following the EB welding process, leak and burst tests were conducted, as was fractography analysis. The welded vessels showed an acceptable holding pressure of 30 MPa, with a reasonable residual deformation up to 2.3% and a leak rate better than 1 × 10-8 std-cc s-1 helium. The failures that occurred under longitudinal stresses reflected the presence of two weak locations in the vessels, i.e., the welded joint region and the transition zone between the vessel base and wall. Fractographic analysis of the fracture surfaces of broken vessels displayed the ductile mode of the rupture, with dimples of various sizes, depending on the failure location.

Spent nuclear fuel canister storage building conceptual design report

Energy Technology Data Exchange (ETDEWEB)

Swenson, C.E. [Westinghouse Hanford Co., Richland, WA (United States)

1996-01-01

This Conceptual Design Report provides the technical basis for the Spent Nuclear Fuels Project, Canister Storage Building, and as amended by letter (correspondence number 9555700, M.E. Witherspoon to E.B. Sellers, ``Technical Baseline and Updated Cost Estimate for the Canister Storage Building``, dated October 24, 1995), includes the project cost baseline and Criteria to be used as the basis for starting detailed design in fiscal year 1995.

Spent nuclear fuel canister storage building conceptual design report

International Nuclear Information System (INIS)

Swenson, C.E.

1996-01-01

This Conceptual Design Report provides the technical basis for the Spent Nuclear Fuels Project, Canister Storage Building, and as amended by letter (correspondence number 9555700, M.E. Witherspoon to E.B. Sellers, ''Technical Baseline and Updated Cost Estimate for the Canister Storage Building'', dated October 24, 1995), includes the project cost baseline and Criteria to be used as the basis for starting detailed design in fiscal year 1995

Definitive design report: Design report project W-025, Radioactive Mixed Waste (RMW) Land Disposal Facility NON-DRAG-OFF. Revision 1, Volume 1 and 2

International Nuclear Information System (INIS)

Roscha, V.

1994-01-01

The purpose of this report is to describe the definitive design of the Radioactive Mixed Waste (RMW) Non-Drag-Off disposal facility, Project W-025. This report presents a n of the major landfill design features and a discussion of how each of the criteria is addressed in the design. The appendices include laboratory test results, design drawings, and individual analyses that were conducted in support of the design. Revision 1 of this document incorporates design changes resulting from an increase in the required operating life of the W-025 landfill from 2 to 20 years. The rationale for these design changes is described in Golder Associates Inc. 1991a. These changes include (1) adding a 1.5-foot-thick layer of compacted admix directory-under the primary FML on the floor of the landfill to mitigate the effects of possible stress cracking in the primary flexible membrane liner (FML), and (2) increasing the operations layer thickness from two to three feet over the entire landfill area, to provide additional protection for the secondary admix layer against mechanical damage and the effects of freezing and desiccation. The design of the W-025 Landfill has also been modified in response to the results of the EPA Method 9090 chemical compatibility testing program (Golder Associates Inc. 1991b and 1991c), which was completed after the original design was prepared. This program consisted of testing geosynthetic materials and soil/bentonite admix with synthetic leachate having the composition expected during the life of the W-025 Landfill., The results of this program indicated that the polyester geotextile originally specified for the landfill might be susceptible to deterioration. On this basis, polypropylene geotextiles were substituted as a more chemically-resistant alternative. In addition, the percentage of bentonite in the admix was increased to provide sufficiently low permeability to the expected leachate

Deep Borehole Emplacement Mode Hazard Analysis Revision 0

Energy Technology Data Exchange (ETDEWEB)

Sevougian, S. David [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2015-08-07

This letter report outlines a methodology and provides resource information for the Deep Borehole Emplacement Mode Hazard Analysis (DBEMHA). The main purpose is identify the accident hazards and accident event sequences associated with the two emplacement mode options (wireline or drillstring), to outline a methodology for computing accident probabilities and frequencies, and to point to available databases on the nature and frequency of accidents typically associated with standard borehole drilling and nuclear handling operations. Risk mitigation and prevention measures, which have been incorporated into the two emplacement designs (see Cochran and Hardin 2015), are also discussed. A key intent of this report is to provide background information to brief subject matter experts involved in the Emplacement Mode Design Study. [Note: Revision 0 of this report is concentrated more on the wireline emplacement mode. It is expected that Revision 1 will contain further development of the preliminary fault and event trees for the drill string emplacement mode.

Statistical aspects of quantitative real-time PCR experiment design

Czech Academy of Sciences Publication Activity Database

Kitchen, R.R.; Kubista, Mikael; Tichopád, Aleš

2010-01-01

Roč. 50, č. 4 (2010), s. 231-236 ISSN 1046-2023 R&D Projects: GA AV ČR IAA500520809 Institutional research plan: CEZ:AV0Z50520701 Keywords : Real-time PCR * Experiment design * Nested analysis of variance Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.527, year: 2010

Mechanical properties of EB-PVD ZrO{sub 2} thermal barrier coatings; Mechanische Eigenschaften von EB-PVD ZrO{sub 2} Waermedaemmschichten

Energy Technology Data Exchange (ETDEWEB)

Held, Carolin

2014-08-29

In this work, the elastic properties of thermal barrier coatings which were produced by electron-beam enhanced physical vapour deposition were investigated, as well as the dependency of the properties on the sample microstructure, the thermal treatment and the test method. For this purpose, not only commercial coatings were characterized, but also special sample material was used which consists of a 1 mm thick layer of EB-PVD TBC. This material was isothermally heat treated for different times at 950 C, 1100 C and 1200 C and then tested in a specially developed miniaturized bend test and by dynamic mechanical analysis. The sample material was tested by nanoindentation in order to measure the Young's modulus on a local scale, and the porosity of the samples was determined by microstructure analysis and porosimetry. The decrease of porosity could be connected with sintering and subsequent stiffening of the material. The test results are dependent on the tested volume. A small test volume leads to larger measured Young's moduli, while a large test volume yields lower values. The test volume also has an influence on the increase of stiffness during thermal exposure. With a small tested volume, a quicker increase of the Young's modulus was registered, which could be associated to the sintering of local structures.

A phase I/II study of external beam radiation, brachytherapy and concurrent chemotherapy in localized cancer of the esophagus (RTOG 9207)

International Nuclear Information System (INIS)

Gaspar, L.E.; Qian, C.; Kocha, W.I.; Coia, L.R.; Herskovic, A.; Graham, M.

1996-01-01

Introduction: A multi-institutional, prospective study was designed to determine the feasibility and toxicity of chemotherapy, external beam irradiation and esophageal brachytherapy (EB) in a potentially curable group of patients with adenocarcinoma or squamous cell carcinoma of the esophagus. Methods: Planned treatment was 50 Gy external beam radiation (25 fractions/5 wks) followed 2 weeks later by EB (either HDR 5 Gy wks 8,9 and 10 for a total of 15 Gy or LDR 20 Gy wk 8). The protocol was later revised to delete the LDR alternative due to poor accrual and decrease the HDR dose to 10 Gy, ie 5 Gy wks 8 and 9. Chemotherapy was given wks 1,5,8 and 11 with DDP 75 mg/m2 and 5-FU 1000 mg/m2/24 hrs, 96 hour infusion. Data is available on 50 patients (46 squamous, 3 adenocarcinoma) treated on the HDR alternative (EB dose 15 Gy and 10 Gy in 40 and 10 patients, respectively. Results: Thirty-five patients (70%) were able to complete external beam, EB and at least 2 courses of chemotherapy. Estimated survival rate at 12 months is 48%. Life-threatening toxicity or death occurred in 13 (26%) and 4 (8%) patients, respectively. Treatment-related esophageal fistulas occurred in 6 patients (12%) at 0.5 to 6.2 months from the first day of brachytherapy, leading to death in 3. So far all treatment-related fistulas occurred in the 15 Gy EB group. Conclusions: Survival following this combination of chemotherapy, external beam radiation and EB does not appear to be different from survival seen following chemotherapy and external beam radiation only. Based on the high incidence of fistulas, we urge extreme caution in employing EB as a boost following concurrent chemotherapy and external beam radiation with the schema utilized in this prospective study

Supplemental design requirements document, Project W026

International Nuclear Information System (INIS)

Weidert, J.R.

1993-01-01

This document supplements and extends the Functional Design Criteria, SP-W026-FDC-001, for the Waste Receiving and Processing Facility (WRAP), Module 1. It provides additional detailed requirements, summarizes key Westinghouse Hanford Company design guidance, and establishes baseline technical agreements to be used in definitive design of the WRAP-1 facility. Revision 3 of the Supplemental Design Requirements Document has been assigned an Impact Level of 3ESQ based on the content of the entire revision. The actual changes made from Revision 2 have an Impact Level of 3S and the basis for these changes was previously reviewed and approved per WHC correspondence No. 9355770

75 FR 24786 - List of Approved Spent Fuel Storage Casks: NUHOMS® HD System Revision 1

Science.gov (United States)

2010-05-06

... Fuel Storage Casks: NUHOMS[supreg] HD System Revision 1 AGENCY: Nuclear Regulatory Commission. ACTION... storage regulations by revising the Transnuclear, Inc. (TN) NUHOMS[supreg] HD System listing within the... System cask design within the list of approved spent fuel storage casks that power reactor licensees can...

76 FR 31887 - Procedures by Which the Agricultural Marketing Service Develops, Revises, Suspends, or Terminates...

Science.gov (United States)

2011-06-02

... format consistent with recent revisions of other U.S. grade standards. This format has been designed to...''. These changes would provide a uniform format consistent with recent revisions of other U.S. grade standards. The term, ``Hard, woody okra material'' would be added to the standards. These terms and...

Revision of the Genus Hybosorus Macleay (Coleoptera: Scarabaeidae, Hybosorinae)

NARCIS (Netherlands)

Kuijten, P.J.

1983-01-01

A taxonomic revision of the scarabaeoid genus Hybosorus is given, including descriptions, nomenclatorial notes, figures of genital apparatus and other relevant parts, a key, and notes on distribution and bionomics. Lectotypes are designated for Hybosorus carolinus LeConte, H. crassus Klug, H.

Revising Lecture Notes: How Revision, Pauses, and Partners Affect Note Taking and Achievement

Science.gov (United States)

Luo, Linlin; Kiewra, Kenneth A.; Samuelson, Lydia

2016-01-01

Note taking has been categorized as a two-stage process: the recording of notes and the review of notes. We contend that note taking might best involve a three-stage process where the missing stage is revision. This study investigated the benefits of revising lecture notes and addressed two questions: First, is revision more effective than…

Nové sídliště lidu kultury s vypíchanou keramikou v Rouchovanech na Třebíčsku

Czech Academy of Sciences Publication Activity Database

Holub, M.; Kaiser, L.; Kočár, Petr; Kočárová, R.; Vokáč, M.; Vokáčová, J.

2013-01-01

Roč. 2013, č. 6 (2013), s. 7-15 ISSN 1804-2953 Institutional support: RVO:67985912 Keywords : Rouchovany * Třebíč region * archaeology * archaeobotany * archaeozoology * Neolithic * Stroked Pottery Culture Subject RIV: AC - Archeology, Anthropology, Ethnology

Revision of the ASME nuclear quality assurance standard and its historical background

International Nuclear Information System (INIS)

Suzuki, Tetsuya

2009-01-01

ASME NQA-1-2008 'Quality Assurance Requirements for Nuclear Facility Applications' will be endorsed by US NRC by the end of 2009. This standard will apply to design, construction and operation of nuclear power plants newly erected in USA. It is important to Japanese vendors developing nuclear business in USA. Historical background, significance of revision and main revised points of the ASME nuclear quality assurance standard are described in the present paper. (T. Tanaka)

Closed cooling water chemistry guidelines revision

International Nuclear Information System (INIS)

McElrath, Joel; Breckenridge, Richard

2014-01-01

This second revision of the Closed Cooling Water Chemistry Guideline addresses the use of chemicals and monitoring methods to mitigate corrosion, fouling, and microbiological growth in the closed cooling-water (CCW) systems of nuclear and fossil-fueled power plants. This revision has been endorsed by the utility chemistry community and represents another step in developing a more proactive chemistry program to limit or control closed cooling system degradation with increased consideration of corporate resources and plant-specific design and operating concerns. These guidelines were developed using laboratory data, operating experience, and input from organizations and utilities within and outside of the United States of America. It is the intent of the Revision Committee that these guidelines are applicable to all nuclear and fossil-fueled generating stations around the world. A committee of industry experts—including utility specialists, Institute of Nuclear Power Operations representatives, water-treatment service-company representatives, consultants, a primary contractor, and EPRI staff—collaborated in reviewing available data on closed cooling-water system corrosion and microbiological issues. Recognizing that each plant owner has a unique set of design, operating, and corporate concerns, the Guidelines Committee developed a methodology for plant-specific optimization. The guideline provides the technical basis for a reasonable but conservative set of chemical treatment and monitoring programs. The use of operating ranges for the various treatment chemicals discussed in this guideline will allow a power plant to limit corrosion, fouling, and microbiological growth in CCW systems to acceptable levels. The guideline now includes closed cooling chemistry regimes proven successful in use in the international community. The guideline provides chemistry constraints for the use of phosphates control, as well as pure water with pH control. (author)

Acetabular Cup Revision.

Science.gov (United States)

Kim, Young-Ho

2017-09-01

The use of acetabular cup revision arthroplasty is on the rise as demands for total hip arthroplasty, improved life expectancies, and the need for individual activity increase. For an acetabular cup revision to be successful, the cup should gain stable fixation within the remaining supportive bone of the acetabulum. Since the patient's remaining supportive acetabular bone stock plays an important role in the success of revision, accurate classification of the degree of acetabular bone defect is necessary. The Paprosky classification system is most commonly used when determining the location and degree of acetabular bone loss. Common treatment options include: acetabular liner exchange, high hip center, oblong cup, trabecular metal cup with augment, bipolar cup, bulk structural graft, cemented cup, uncemented cup including jumbo cup, acetabular reinforcement device (cage), trabecular metal cup cage. The optimal treatment option is dependent upon the degree of the discontinuity, the amount of available bone stock and the likelihood of achieving stable fixation upon supportive host bone. To achieve successful acetabular cup revision, accurate evaluation of bone defect preoperatively and intraoperatively, proper choice of method of acetabular revision according to the evaluation of acetabular bone deficiency, proper technique to get primary stability of implant such as precise grafting technique, and stable fixation of implant are mandatory.

76 FR 2243 - List of Approved Spent Fuel Storage Casks: NUHOMS ® HD System Revision 1

Science.gov (United States)

2011-01-13

... Storage Casks: NUHOMS [supreg] HD System Revision 1 AGENCY: Nuclear Regulatory Commission. ACTION: Direct... fuel storage regulations by revising the Transnuclear, Inc. (TN) NUHOMS [supreg] HD System listing... NUHOMS [supreg] HD System cask design listed in Sec. 72.214 (List of approved spent fuel storage casks...

Failure of aseptic revision total knee arthroplasties.

Science.gov (United States)

Leta, Tesfaye H; Lygre, Stein Håkon L; Skredderstuen, Arne; Hallan, Geir; Furnes, Ove

2015-02-01

In Norway, the proportion of revision knee arthroplasties increased from 6.9% in 1994 to 8.5% in 2011. However, there is limited information on the epidemiology and causes of subsequent failure of revision knee arthroplasty. We therefore studied survival rate and determined the modes of failure of aseptic revision total knee arthroplasties. This study was based on 1,016 aseptic revision total knee arthroplasties reported to the Norwegian Arthroplasty Register between 1994 and 2011. Revisions done for infections were not included. Kaplan-Meier and Cox regression analyses were used to assess the survival rate and the relative risk of re-revision with all causes of re-revision as endpoint. 145 knees failed after revision total knee arthroplasty. Deep infection was the most frequent cause of re-revision (28%), followed by instability (26%), loose tibial component (17%), and pain (10%). The cumulative survival rate for revision total knee arthroplasties was 85% at 5 years, 78% at 10 years, and 71% at 15 years. Revision total knee arthroplasties with exchange of the femoral or tibial component exclusively had a higher risk of re-revision (RR = 1.7) than those with exchange of the whole prosthesis. The risk of re-revision was higher for men (RR = 2.0) and for patients aged less than 60 years (RR = 1.6). In terms of implant survival, revision of the whole implant was better than revision of 1 component only. Young age and male sex were risk factors for re-revision. Deep infection was the most frequent cause of failure of revision of aseptic total knee arthroplasties.

Influence of prosthesis design and implantation technique on implant stresses after cementless revision THR

Directory of Open Access Journals (Sweden)

Duda Georg N

2011-05-01

Full Text Available Abstract Background Femoral offset influences the forces at the hip and the implant stresses after revision THR. For extended bone defects, these forces may cause considerable bending moments within the implant, possibly leading to implant failure. This study investigates the influences of femoral anteversion and offset on stresses in the Wagner SL revision stem implant under varying extents of bone defect conditions. Methods Wagner SL revision stems with standard (34 mm and increased offset (44 mm were virtually implanted in a model femur with bone defects of variable extent (Paprosky I to IIIb. Variations in surgical technique were simulated by implanting the stems each at 4° or 14° of anteversion. Muscle and joint contact forces were applied to the reconstruction and implant stresses were determined using finite element analyses. Results Whilst increasing the implant's offset by 10 mm led to increased implant stresses (16.7% in peak tensile stresses, altering anteversion played a lesser role (5%. Generally, larger stresses were observed with reduced bone support: implant stresses increased by as much as 59% for a type IIIb defect. With increased offset, the maximum tensile stress was 225 MPa. Conclusion Although increased stresses were observed within the stem with larger offset and increased anteversion, these findings indicate that restoration of offset, key to restoring joint function, is unlikely to result in excessive implant stresses under routine activities if appropriate fixation can be achieved.

Nuclear Regulatory Commission Human Factors Program Plan. Revision 2

International Nuclear Information System (INIS)

1986-04-01

This document is the Second Annual Revision to the NRC Human Factors Program Plan. The first edition was published in August 1983. Revision 1 was published in July of 1984. Purpose of the NRC Human Factors Program is to ensure that proper consideration is given to human factors in the design and operation of nuclear power plants. This document describes the plans of the Office of Nuclear Reactor Regulation to address high priority human factors concerns of importance to reactor safety in FY 1986 and FY 1987. Revision 2 of the plan incorporates recent Commission decisions and policies bearing on the human factors aspects of reactor safety regulation. With a few exceptions, the principal changes from prior editions reflect a shift from developing new requirements to staff evaluation of industry progress in resolving human factors issues. The plan addresses seven major program elements: (1) Training, (2) Licensing Examinations, (3) Procedures, (4) Man-Machine Interface, (5) Staffing and Qualifications, (6) Management and Organization, and (7) Human Performance

Mechanical properties of EB-PVD ZrO{sub 2} thermal barrier coatings; Mechanische Eigenschaften von EB-PVD ZrO{sub 2} Waermedaemmschichten

Energy Technology Data Exchange (ETDEWEB)

Held, Carolin

2014-08-29

In this work, the elastic properties of thermal barrier coatings which were produced by electron-beam enhanced physical vapour deposition were investigated, as well as the dependency of the properties on the sample microstructure, the thermal treatment and the test method. For this purpose, not only commercial coatings were characterized, but also special sample material was used which consists of a 1 mm thick layer of EB-PVD TBC. This material was isothermally heat treated for different times at 950 C, 1100 C and 1200 C and then tested in a specially developed miniaturized bend test and by dynamic mechanical analysis. The sample material was tested by nanoindentation in order to measure the Young's modulus on a local scale, and the porosity of the samples was determined by microstructure analysis and porosimetry. The decrease of porosity could be connected with sintering and subsequent stiffening of the material. The test results are dependent on the tested volume. A small test volume leads to larger measured Young's moduli, while a large test volume yields lower values. The test volume also has an influence on the increase of stiffness during thermal exposure. With a small tested volume, a quicker increase of the Young's modulus was registered, which could be associated to the sintering of local structures.

Graphic Design Career Guide 2. Revised Edition.

Science.gov (United States)

Craig, James

The graphic design field is diverse and includes many areas of specialization. This guide introduces students to career opportunities in graphic design. The guide is organized in four parts. "Part One: Careers in Graphic Design" identifies and discusses the various segments of the graphic design industry, including: Advertising, Audio-Visual, Book…

Structure-based drug design of selective 5´-nucleotidases inhibitors

Czech Academy of Sciences Publication Activity Database

Pachl, Petr; Brynda, Jiří; Rosenberg, Ivan; Fábry, Milan; Řezáčová, Pavlína

2011-01-01

Roč. 18, č. 1 (2011), s. 33-34 ISSN 1211-5894. [Discussions in Structural Molecular Biology /9./. 24.03.2011-26.03.2011, Nové Hrady] Institutional research plan: CEZ:AV0Z40550506; CEZ:AV0Z50520701 Keywords : inhibitor design * nucleotidase * Xray crystalography Subject RIV: EB - Genetics ; Molecular Biology

Identifying Indicators Related to Constructs for Engineering Design Outcome

Science.gov (United States)

Wilhelmsen, Cheryl A.; Dixon, Raymond A.

2016-01-01

This study ranked constructs articulated by Childress and Rhodes (2008) and identified the key indicators for each construct as a starting point to explore what should be included on an instrument to measure the engineering design process and outcomes of students in high schools that use the PLTW and EbDTM curricula in Idaho. A case-study design…

Ergonomic evaluation of pilot oxygen mask designs

NARCIS (Netherlands)

Lee, W.; Yang, Xiaopeng; Jung, Daehan; Park, Seikwon; Kim, Heeeun; You, Heecheon

2018-01-01

A revised pilot oxygen mask design was developed for better fit to the Korean Air Force pilots’ faces. The present study compared an existing pilot oxygen mask and a prototype of the revised mask design with 88 Korean Air Force pilots in terms of subjective discomfort, facial contact pressure,

Characterization and evaluation of EB-PVD thermal barrier coatings by impedance spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Zhang Chunxia; Liu Fushun; Gong Shengkai; Xu Huibin [School of Materials Science and Engineering, Beihang Univ., Beijing, BJ (China)

2005-07-01

Two layer thermal barrier coatings (TBCs) were prepared by EB-PVD (electron beam-physical vapor deposition) at different substrate temperatures in the range of 823 to 1123 K, and their microstructure was investigated with SEM and AC impedance as a function of substrate temperature and thermal cycling time. YSZ layer of all TBCs samples is in column structure, but the grain size and growth orientation are different with substrate. In this research, impedance spectra (IS) was measured as a function of thermal cycling between 1323 K and 298 K for these thermal barrier coatings. Grain boundary and bulk can be distinguished from analysis of AC impedance spectroa to provide information about the relation between microstructure and electric properties. The change in IS until failure was found to be related with the thickness, microcracks and macrocracks of TGO and the change in the interfacial of TGO/YSZ. (orig.)

Proceedings of the FNCA 2005 workshop on application of electron accelerator. EB treatment of wastewater

International Nuclear Information System (INIS)

Yoshii, Fumio; Kume, Tamikazu

2006-08-01

'Forum for Nuclear Cooperation in Asia (FNCA) Workshop on Application of Electron Accelerator' was sponsored by the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. The 2005 workshop was jointly organized by the Ministry of Science and Technology (MOST), Korea, Korea Atomic Energy Research Institute and Japan Atomic Energy Agency (JAEA). It was held at the International Nuclear Technology and Education Center (INTEC/KAERI), Daejeon, Korea from 14 to 18 November 2005. The Workshop was attended by 32 experts on application of electron accelerator from each of the participating countries, i.e., China (1), Indonesia (1), Korea (18), Malaysia (2), Philippines (1), Thailand (1) and Vietnam (1), and 7 participants from Japan. On the first day, a National Executive Management Seminar on Application of Electron Accelerator was held and attended by 45 participants. Total of 20 papers including Seminar lectures, invited papers on wastewater treatment by electron beam, and country reports on EB irradiation system were presented. The major areas of interest of FNCA member states for cooperation were identified for application of low energy electron accelerator to liquids (natural polymer, wastewater), solids (hydrogel, thin film) and gases (flue gas). Based on the evaluation and proposal from the participating countries, discussions were carried out to re-formulate the work plan of the project on natural polymers and wastewater for three years until FY 2008. It was agreed the FNCA 2006 workshop on EB crosslinking of natural polymers would be held in Malaysia. All manuscripts submitted by every speaker were included in the proceedings. The 18 presented papers are indexed individually. (J.P.N.)

A revised Self- and Family Management Framework.

Science.gov (United States)

Grey, Margaret; Schulman-Green, Dena; Knafl, Kathleen; Reynolds, Nancy R

2015-01-01

Research on self- and family management of chronic conditions has advanced over the past 6 years, but the use of simple frameworks has hampered the understanding of the complexities involved. We sought to update our previously published model with new empirical, synthetic, and theoretical work. We used synthesis of previous studies to update the framework. We propose a revised framework that clarifies facilitators and barriers, processes, proximal outcomes, and distal outcomes of self- and family management and their relationships. We offer the revised framework as a model that can be used in studies aimed at advancing self- and family management science. The use of the framework to guide studies would allow for the design of studies that can address more clearly how self-management interventions work and under what conditions. Copyright © 2015 Elsevier Inc. All rights reserved.

Designing Critique for Knowledge Integration

Science.gov (United States)

Sato, Mie Elissa

Generating explanations is central to science and has the potential to have a powerful impact on students' conceptual understanding in science instruction. However, improving conceptual understanding by generating explanations is a fraught affair: students may struggle with the sense of false clarity that may arise from generating explanations, fail to detect gaps in their understanding, and dismiss salient information that contradict their beliefs. Critiquing explanations has the potential to counteract these pitfalls by exposing students to alternative ideas to contrast with their own. This dissertation seeks to clarify how to design critique in technology-enhanced science instruction to support students in revising their explanations about scientific phenomena, and in doing so, refining their conceptual understanding. Using the Knowledge Integration framework, I revised two technology-enhanced curriculum units, Plate Tectonics and Global Climate Change, in a design partnership between teachers, researchers, and technologists. I conducted a series of studies with sixth-grade students to investigate the conditions under which guided critique of explanations can support revision. The pilot critique study investigated the impact of the revised Plate Tectonics unit on students' understanding of convection, as well as of a preliminary design of critique where students generated and applied their own criteria for what makes a good explanation in science. The guidance study explored how incorporating a complex selection task that features meta-explanatory criteria into critique supports students in distinguishing among different criteria, as well as how students use peer or expert guidance on their initial explanation during revision. The critique study investigated how designing critique with a complex selection task that features plausible alternative ideas and giving guidance on students' critiques support students in distinguishing among a range of relevant ideas

Bibliocable. Revised Edition.

Science.gov (United States)

Cable Television Information Center, Washington, DC.

This selective, annotated bibliography is a revision of the original published in 1972 (ED 071 402). Some 104 books, articles, and reports included here deal with access, applications, franchising, regulation, technology, and other aspects of cable television. The listings are of two types in each category. First are revisions of the original…

Surface characteristics of hydroxyapatite-coated layer prepared on nanotubular Ti–35Ta–xHf alloys by EB-PVD

Energy Technology Data Exchange (ETDEWEB)

Jeong, Yong-Hoon [Department of Dental Materials and Research Center of Nano-Interface Activation for Biomaterials, School of Dentistry, Chosun University, Gwangju (Korea, Republic of); Biomechanics and Tissue Engineering Laboratory, Division of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH (United States); Moon, Byung-Hak [Department of Dental Materials and Research Center of Nano-Interface Activation for Biomaterials, School of Dentistry, Chosun University, Gwangju (Korea, Republic of); Choe, Han-Cheol, E-mail: hcchoe@chosun.ac.kr [Department of Dental Materials and Research Center of Nano-Interface Activation for Biomaterials, School of Dentistry, Chosun University, Gwangju (Korea, Republic of); Brantley, William A. [Division of Restorative, Prosthetic and Primary Care Dentistry, College of Dentistry, The Ohio State University, Columbus, OH (United States)

2013-12-31

In this study, we investigated the surface characteristics of hydroxyapatite (HA)-coated layers prepared by electron-beam physical vapor deposition (EB-PVD) on nanotubular Ti–35Ta–xHf alloys (x = 3, 7, and 15 wt.%). Ti–35Ta–xHf alloys were first prepared by arc melting. Formation of a nanotube structure on these alloys was achieved by an electrochemical method in 1 M H{sub 3}PO{sub 4} + 0.8 wt.% NaF electrolytes. The HA coatings were then deposited on the nanotubular surface by an EB-PVD method. The surface characteristics were analyzed by field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction (XRD). The electrochemical behavior was examined using a potentiodynamic polarization test in 0.9% NaCl solution. The Ti–35Ta–xHf alloys had an equiaxed grain structure with α″ + β phases, and the α″ phase disappeared with increases in Hf content. The Ti–35Ta–15Hf alloy showed higher β-phase peak intensity in the XRD patterns than that for the lower Hf-content alloys. A highly ordered nanotubular oxide layer was formed on the Ti–35Ta–15Hf alloy, and the tube length depended on Hf content. The HA coating surface formed at traces of the nanotubular titanium oxide layer and completely covered the tips of the nanotubes with a cluster shape. From the potentiodynamic polarization tests, the incorporation of Hf element and formation of the nanotubular structure were the main factors for achieving lower current density. In particular, the surface of the HA coating on the nanotubular structure exhibited higher corrosion resistance than that of the nanotubular titanium oxide structure without an HA coating. - Highlights: • Hydroxyapatite (HA) was coated on nanotubular Ti–35Ta–xHf alloys, using EB-PVD. • Increasing the Hf content reduced the relative proportion of α″ martensite to β-Ti in the microstructures. • The detailed nanotubular structure formed by anodization depended on alloy composition

Surface characteristics of hydroxyapatite-coated layer prepared on nanotubular Ti–35Ta–xHf alloys by EB-PVD

International Nuclear Information System (INIS)

Jeong, Yong-Hoon; Moon, Byung-Hak; Choe, Han-Cheol; Brantley, William A.

2013-01-01

In this study, we investigated the surface characteristics of hydroxyapatite (HA)-coated layers prepared by electron-beam physical vapor deposition (EB-PVD) on nanotubular Ti–35Ta–xHf alloys (x = 3, 7, and 15 wt.%). Ti–35Ta–xHf alloys were first prepared by arc melting. Formation of a nanotube structure on these alloys was achieved by an electrochemical method in 1 M H 3 PO 4 + 0.8 wt.% NaF electrolytes. The HA coatings were then deposited on the nanotubular surface by an EB-PVD method. The surface characteristics were analyzed by field-emission scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction (XRD). The electrochemical behavior was examined using a potentiodynamic polarization test in 0.9% NaCl solution. The Ti–35Ta–xHf alloys had an equiaxed grain structure with α″ + β phases, and the α″ phase disappeared with increases in Hf content. The Ti–35Ta–15Hf alloy showed higher β-phase peak intensity in the XRD patterns than that for the lower Hf-content alloys. A highly ordered nanotubular oxide layer was formed on the Ti–35Ta–15Hf alloy, and the tube length depended on Hf content. The HA coating surface formed at traces of the nanotubular titanium oxide layer and completely covered the tips of the nanotubes with a cluster shape. From the potentiodynamic polarization tests, the incorporation of Hf element and formation of the nanotubular structure were the main factors for achieving lower current density. In particular, the surface of the HA coating on the nanotubular structure exhibited higher corrosion resistance than that of the nanotubular titanium oxide structure without an HA coating. - Highlights: • Hydroxyapatite (HA) was coated on nanotubular Ti–35Ta–xHf alloys, using EB-PVD. • Increasing the Hf content reduced the relative proportion of α″ martensite to β-Ti in the microstructures. • The detailed nanotubular structure formed by anodization depended on alloy composition. • The

Assessing Whether Students Seek Constructive Criticism: The Design of an Automated Feedback System for a Graphic Design Task

Science.gov (United States)

Cutumisu, Maria; Blair, Kristen P.; Chin, Doris B.; Schwartz, Daniel L.

2017-01-01

We introduce a choice-based assessment strategy that measures students' choices to seek constructive feedback and to revise their work. We present the feedback system of a game we designed to assess whether students choose positive or negative feedback and choose to revise their posters in the context of a poster design task, where they learn…

Proceedings of the FNCA 2004 workshop on application of electron accelerator. EB treatment of flue gases

International Nuclear Information System (INIS)

Yoshii, Fumio; Kume, Tamikazu

2005-06-01

'Forum for Nuclear Cooperation in Asia (FNCA) Workshop on Application of Electron Accelerator' was sponsored by the Ministry of Education, Culture, Sports, Science and Technology (MEXT). The 2004 workshop was jointly organized by China Atomic Energy Authority (CAEA), Institute of Modern Physics/Chinese Academy of Sciences(IMP-CAS) and Japan Atomic Energy Research Institute (JAERI). It was held at Prime Hotel, Beijing, China from 6 to 10 September 2004. The Workshop was attended by 28 experts on application of electron accelerator from each of the participating countries, i.e., China, Indonesia, Korea, Malaysia, The Philippines, Thailand and Vietnam, and 10 participants from Japan. On the first day, a National Executive Management Seminar on Application of Electron Accelerator was held and attended by 67 participants. Total of 20 papers including Seminar lectures, invited papers on flue gas treatment by electron beam, and country reports on EB irradiation system were presented. The major areas of interest of FNCA member states for cooperation were identified for application of low energy electron accelerator as liquid (natural polymer, wastewater), solid (hydrogel, thin film) and gases (flue gas). Based on the proposal from the participating countries, discussions were carried out to re-formulate the work plan of the project for three years until FY 2005. It was agreed the FNCA 2005 workshop on EB treatment of wastewater will be held in Korea. All manuscripts submitted by every speaker were included in the proceedings. The 20 of the presented papers are indexed individually. (J.P.N.)

The Subunit Principle in Scar Face Revision.

Science.gov (United States)

Elshahat, Ahmed; Lashin, Riham

2017-06-01

Facial scaring is considered one of the most difficult cosmetic problems for any plastic surgeon to solve. The condition is more difficult if the direction of the scar is not parallel to relaxed skin tension lines. Attempts to manage this difficult situation included revisions using geometric designs, Z plasties or W plasties to camouflage the straight line visible scaring. The use of long-lasting resorbable sutures was tried too. Recently, the use of botulinum toxin during revision improved the results. Fractional CO2 lasers, microfat grafts, and platelet-rich plasma were added to the armamentarium. The scar is least visible if placed in the junction between the facial subunits. The aim of this study is to investigate the use of the subunit principle to improve the results of scar revision. Four patients were included in this study. Tissue expansion of the intact part of the subunit allowed shifting the scar to the junction between the affected subunit and the adjacent one. Tissue expansion, delivery of the expanders, and advancement of the flaps were successful in all patients. The fact that this is a 2-stage procedure and sacrifices some of the intact skin from the affected facial subunit, makes this technique reserved to patients with ugly facial scars who are ambitious to improve their appearance.

At-risk children's use of reflection and revision in hands-on experimental activities

Science.gov (United States)

Petrosino, Anthony J., Jr.

The goal of this study was to investigate the effects of incorporating opportunities for reflection and revision in hands-on science instruction which emphasized experimentation using model rockets. The participants were low achieving sixth grade summer school students (n = 23) designated as at-risk for school failure by their district. The group was asked a series of interview questions based on work by Schauble et al. (1995) relating to experimentation. The interviews took place over three distinct time points corresponding to a "hands-on only" condition, a "hands-on with reflection and revision" condition and a "hands-on with repeated reflection and revision" condition. A Friedman's Two-Way Analysis of Variance by Ranks indicate students score low at first with traditional hands-on instruction but improve significantly with opportunities to reflect and revise their experiments. In addition, a sociocultural analysis was conducted during the summer school session to assess the model rocket activity as an apprenticeship, as guided participation and as participatory appropriation using a framework established by Rogoff (1994). Finally, a survey (the Classroom Environment Survey) was administered to the students measuring five constructs consistent with a constructivist classroom: participation, autonomy, relevance, commitment to learning and disruptions to learning. Analysis indicate students in the summer school model rocket intervention experienced a greater sense of constructivist principles during the activity than a similar comparison group utilizing reform minded instruction but not including opportunities for reflection and revision cycles. This research provides important evidence that, like scientists, students in school can learn effectively from extended practice in a varied context. Importantly, the data indicate that hands-on instruction is best utilized when opportunities for reflection and revision are made explicit. Implications are discussed related

Electron-beam and combined e-b and microwave processing of dried food ingredients

International Nuclear Information System (INIS)

Ferdes, O.; Minea, R.; Martin, D.; Tirlea, A.; Badea, M.; Oproiu, C.

1998-01-01

Complete text of publication follows. There are summarized and presented the results on the irradiated dried food ingredients, as starches, flour, spices, enzymes, pigments. It has investigated the electron-beam and microwave processing to achieve the hygienic and microbiological quality requirements for these materials. There are presented the results regarding the e-b and microwave effects on the main specific parameters (nutritional; microbiological; physical and chemical) for each item. Irradiation has carried out to different electron accelerators, mainly to ALIN-7 linac (W e ∼6 MeV) and using a special designed microwave equipment (2.45 GHz magnetron of 850 W maximum output power). The samples have been irradiated up to 25 kGy (dose rate ∼ 2.0 kGy/min) and there were treated by microwaves (250 W-550 W) for different exposure time. There have analyzed and presented the influence of these two physical fields on some common physical, biochemical and microbiological properties (mainly the total germ count, CFU/g) of these food materials. The main technological and physical characteristics of the materials are preserved, under irradiation up to 10 kGy and microwave treatment in the case of satisfying the national requirements for food and food grade additives microbiological load. The combined treatment seems to be present a synergistic effect arising on non-thermal basis. From these results it could be pointed out that electron-beam and microwave treatment is feasible and represents an alternative to other hygienization techniques for the dried food ingredients. It should be considered that combined treatments lead to reducing irradiation dose without losing the microbicidal effects

On the dimensioning of steel construction considering revision of German standards

International Nuclear Information System (INIS)

Lindhorst, L.; Schaudinn, L.; Milleder, J.

2005-01-01

Different procedures for dimensioning of structural steelwork are investigated in this paper. In the non-nuclear area, there has been made a change in the design concept for structural steelwork of surface constructions in Germany and the deterministic design concept of German DIN 18800 (03/81) [1] has been replaced by the semi-probabilistic design concept of DIN 18800 (11/90) [2]. Design codes established in nuclear safety standards for steelwork in German nuclear facilities are considered in the paper. Recent revisions of German nuclear safety standards and specifications are discussed with respect to regulations concerning design codes. The change in design concept for structural steelwork (non-nuclear) has not been adopted in recent revisions of nuclear safety standards and specifications for steelwork of components with importance to safety. The deterministic concept of DIN 18800 (03/81) [1] is compared with the semi-probabilistic concept of DIN 18800 (11/90) [2]. Differences between the standards [1] and [2] are investigated using an example of a steel construction. Results for dimensioning according to DIN 18800 (03/81) [1] are compared to those for dimensioning according to DIN 18800 (11/90) [2] putting the main emphasis on stress analysis and building structure interaction loads. (authors)

Prospects of utilization of EB irradiation technology to augment control of SO2 and other emissions from Chilean copper smelting plants

International Nuclear Information System (INIS)

Villanueva, L.; Ahumada, L.; Ellison, W.; Chmielewski, A.G.; Zimek, Z.

1997-01-01

A technical study including testing and cost analysis for commercial use of selected processes has been conducted. Analysis, affirmation and evaluation of potential utilization of applicable SO 2 -removal process for off-gases, including electron-beam irradiation, for incrementally improving abatement of SO 2 /SO 3 emissions from existing copper smelting facilities in Chile has been carried out. Off-gases are characterized by SO 2 content higher than 3,000 ppm, a complex chemical composition and highly oxidizing conditions, along with cyclical and fluctuating generation. Laboratory tests with simulated high-SO 2 -content process were performed at Institute of Nuclear Chemistry and Technology. Test work proved the technical feasibility of removing SO 2 from (ultra-high SO 2 contents) gases by E-beam irradiation with ammonia injection. A laboratory unit with flow rate of 20 Nm 3 /h equiped with electron accelerator of 800 keV beam energy was used. Influence of different parameters on SO 2 removal efficiency, like temperature, irradiation dose, ammonia stoichiometry and water vapor content, has been established. Tests covered a high SO 2 content range, 2,000 to 10,000 ppm. A generic schematic design has been devised to system arrangement, performance and control requirements. It encompasses upgrading of in-plant ventilation to the extent required by health standards, together with gas cleaning system incorporating the EB Process. The arrangement of the facilities provides for gathering and treating off-gas from selected fugitive emission sources on a continuos basis, at the same time in-drafting a minimum amount of tramp air. An introductory dry dedusting stage, when required, uses condictioned activated carbon injection in conjunction with a fabric filter to efficiently treat raw gas and remove heavy metals, including arsenic, along with particulate matter. Main conclusion of stages of this work is that the EB Process is a simple and appropriate, cost

Improved mechanical properties of Ni-rich Ni3Al coatings produced by EB-PVD for repairing single crystal blades

Institute of Scientific and Technical Information of China (English)

Jing-Yong Sun; Yan-Ling Pei; Shu-Suo Li; Hu Zhang; Sheng-Kai Gong

2017-01-01

Active control of turbine blade tip clearance for aircraft engine continues to be a concern in engine operation,because turbine blades are subjected to wear and therefore cause an increasing tip clearance between the rotating blades and the shroud and also reduce the engine efficiency.In this work,a Ni-rich Ni3Al coating with γ'/γtwo-phase microstructure was deposited by electron beam physical vapor deposition (EB-PVD),which worked as repairing the worn blade tips of single crystal blades.Nb molten pool was used to increase the molten pool temperature and thus to enhance the deposition rate.The microstructures and mechanical properties can be modified by the deposition temperatures and the following heat treatments.All coatings consist of γ'and γ phases.At deposition temperature of 600 ℃,a dense microstructure can be achieved to produce a coating with grain size of ～ 1 μm and microhardness of ～HV 477.After being heated for 4 h at a temperature of 1,100 ℃,the coatings have a more uniform microstructure,and microhardness maintains at a high level of ～ HV 292.Effect of Hf and Zr on EB-PVD Ni3Al repair coating will be further investigated.

[Heinike Heinsoo. Mā ja pūd lēväd, meid eb lē : the subject and the predicate in Votic] / Johanna Laakso

Index Scriptorium Estoniae

Laakso, Johanna, 1962-

2012-01-01

Arvustus: Heinike Heinsoo. Mā ja pūd lēväd, meid eb lē : the subject and the predicate in Votic. Tallinn : Teaduste Akadeemia Kirjastus, 2010. (Linguistica Uralica. Supplementary series ; vol. 4)

Outcomes of different bearings in total hip arthroplasty - implant survival, revision causes, and patient-reported outcome

DEFF Research Database (Denmark)

Varnum, Claus

2017-01-01

ceramic-on-ceramic (CoC) THAs comparing them to those of "standard" metal-on-polyethylene (MoP) THAs. Study II: To compare the six-year revision risk for metal-on-metal (MoM) with that for MoP bearings in cementless stemmed THA, and further to study the revision risk for different designs of stemmed Mo...... for the outcome of THA is the type of bearings. This PhD thesis focuses on the influence of different types of bearings on implant survival, revision causes, PROMs, and noises from THA. The aims of the thesis were: Study I: To examine the revision risk and to investigate the causes of revision of cementless......M THAs and the causes of revision. Study III: To examine the association between CoC, MoM, and MoP bearings and both generic and disease-specific PROMs, and furthermore to examine the incidence and types of noises from the three types of bearings and identify the effect of noises on PROM scores. In study...

Peritoneal Dialysis Access Revision in Children: Causes, Interventions, and Outcomes

Science.gov (United States)

Aki, T. Fazil; Azocar, Marta; White, Colin; Harvey, Elizabeth; Mir, Sevgi; Adragna, Marta; Serdaroglu, Erkin; Sinha, Rajiv; Samaille, Charlotte; Vanegas, Juan Jose; Kari, Jameela; Barbosa, Lorena; Bagga, Arvind; Galanti, Monica; Yavascan, Onder; Leozappa, Giovanna; Szczepanska, Maria; Vondrak, Karel; Tse, Kei-Chiu; Schaefer, Franz; Warady, Bradley A.

2017-01-01

Background and objectives Little published information is available about access failure in children undergoing chronic peritoneal dialysis. Our objectives were to evaluate frequency, risk factors, interventions, and outcome of peritoneal dialysis access revision. Design, setting, participants, & measurements Data were derived from 824 incident and 1629 prevalent patients from 105 pediatric nephrology centers enrolled in the International Pediatric Peritoneal Dialysis Network Registry between 2007 and 2015. Results In total, 452 access revisions were recorded in 321 (13%) of 2453 patients over 3134 patient-years of follow-up, resulting in an overall access revision rate of 0.14 per treatment year. Among 824 incident patients, 186 (22.6%) underwent 188 access revisions over 1066 patient-years, yielding an access revision rate of 0.17 per treatment year; 83% of access revisions in incident patients were reported within the first year of peritoneal dialysis treatment. Catheter survival rates in incident patients were 84%, 80%, 77%, and 73% at 12, 24, 36, and 48 months, respectively. By multivariate logistic regression analysis, risk of access revision was associated with younger age (odds ratio, 0.93; 95% confidence interval, 0.92 to 0.95; P<0.001), diagnosis of congenital anomalies of the kidney and urinary tract (odds ratio, 1.28; 95% confidence interval, 1.03 to 1.59; P=0.02), coexisting ostomies (odds ratio, 1.42; 95% confidence interval, 1.07 to 1.87; P=0.01), presence of swan neck tunnel with curled intraperitoneal portion (odds ratio, 1.30; 95% confidence interval, 1.04 to 1.63; P=0.02), and high gross national income (odds ratio, 1.10; 95% confidence interval, 1.02 to 1.19; P=0.01). Main reasons for access revisions included mechanical malfunction (60%), peritonitis (16%), exit site infection (12%), and leakage (6%). Need for access revision increased the risk of peritoneal dialysis technique failure or death (hazard ratio, 1.35; 95% confidence interval, 1

Guidance document for revision of DOE Order 5820.2A, Radioactive Waste Technical Support Program. Revision 1

Energy Technology Data Exchange (ETDEWEB)

Kudera, D.E.; McMurtrey, C.D.; Meagher, B.G.

1993-04-01

This document provides guidance for the revision of DOE Order 5820.2A, ``Radioactive Waste Management.`` Technical Working Groups have been established and are responsible for writing the revised order. The Technical Working Groups will use this document as a reference for polices and procedures that have been established for the revision process. The overall intent of this guidance is to outline how the order will be revised and how the revision process will be managed. In addition, this document outlines technical issues considered for inclusion by a Department of Energy Steering Committee.

Computer Program of SIE ASME-NH (Revision 1.0) Code

Energy Technology Data Exchange (ETDEWEB)

Koo, Gyeong Hoi; Lee, J. H

2008-01-15

In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH) (Revision 1.0), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail.

Computer Program of SIE ASME-NH (Revision 1.0) Code

International Nuclear Information System (INIS)

Koo, Gyeong Hoi; Lee, J. H.

2008-01-01

In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH) (Revision 1.0), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail

Early subsidence of shape-closed hip arthroplasty stems is associated with late revision. A systematic review and meta-analysis of 24 RSA studies and 56 survival studies.

Science.gov (United States)

van der Voort, Paul; Pijls, Bart G; Nieuwenhuijse, Marc J; Jasper, Jorrit; Fiocco, Marta; Plevier, Josepha W M; Middeldorp, Saskia; Valstar, Edward R; Nelissen, Rob G H H

2015-01-01

Few studies have addressed the association between early migration of femoral stems and late aseptic revision in total hip arthroplasty. We performed a meta-regression analysis on 2 parallel systematic reviews and meta-analyses to determine the association between early migration and late aseptic revision of femoral stems. Of the 2 reviews, one covered early migration data obtained from radiostereometric analysis (RSA) studies and the other covered long-term aseptic revision rates obtained from survival studies with endpoint revision for aseptic loosening. Stems were stratified according to the design concept: cemented shape-closed, cemented force-closed, and uncemented. A weighted regression model was used to assess the association between early migration and late aseptic revision, and to correct for confounders. Thresholds for acceptable and unacceptable migration were determined in accordance with the national joint registries (≤ 5% revision at 10 years) and the NICE criteria (≤ 10% revision at 10 years). 24 studies (731 stems) were included in the RSA review and 56 studies (20,599 stems) were included in the survival analysis review. Combining both reviews for the 3 design concepts showed that for every 0.1-mm increase in 2-year subsidence, as measured with RSA, there was a 4% increase in revision rate for the shape-closed stem designs. This association remained after correction for age, sex, diagnosis, hospital type, continent, and study quality. The threshold for acceptable migration of shape-closed designs was defined at 0.15 mm; stems subsiding less than 0.15 mm in 2 years had revision rates of less than 5% at 10 years, while stems exceeding 0.15 mm subsidence had revision rates of more than 5%. There was a clinically relevant association between early subsidence of shape-closed femoral stems and late revision for aseptic loosening. This association can be used to assess the safety of shape-closed stem designs. The published research is not sufficient

The Sandia MEMS passive shock sensor : FY08 design summary.

Energy Technology Data Exchange (ETDEWEB)

Walraven, Jeremy Allen; Baker, Michael Sean; Clemens, Rebecca C.; Mitchell, John Anthony; Brake, Matthew Robert; Epp, David S.; Wittwer, Jonathan W.

2008-11-01

This report summarizes design and modeling activities for the MEMS passive shock sensor. It provides a description of past design revisions, including the purposes and major differences between design revisions but with a focus on Revisions 4 through 7 and the work performed in fiscal year 2008 (FY08). This report is a reference for comparing different designs; it summarizes design parameters and analysis results, and identifies test structures. It also highlights some of the changes and or additions to models previously documented [Mitchell et al. 2006, Mitchell et al. 2008] such as the way uncertainty thresholds are analyzed and reported. It also includes dynamic simulation results used to investigate how positioning of hard stops may reduce vibration sensitivity.

Ventilation Model

International Nuclear Information System (INIS)

Yang, H.

1999-01-01

The purpose of this analysis and model report (AMR) for the Ventilation Model is to analyze the effects of pre-closure continuous ventilation in the Engineered Barrier System (EBS) emplacement drifts and provide heat removal data to support EBS design. It will also provide input data (initial conditions, and time varying boundary conditions) for the EBS post-closure performance assessment and the EBS Water Distribution and Removal Process Model. The objective of the analysis is to develop, describe, and apply calculation methods and models that can be used to predict thermal conditions within emplacement drifts under forced ventilation during the pre-closure period. The scope of this analysis includes: (1) Provide a general description of effects and heat transfer process of emplacement drift ventilation. (2) Develop a modeling approach to simulate the impacts of pre-closure ventilation on the thermal conditions in emplacement drifts. (3) Identify and document inputs to be used for modeling emplacement ventilation. (4) Perform calculations of temperatures and heat removal in the emplacement drift. (5) Address general considerations of the effect of water/moisture removal by ventilation on the repository thermal conditions. The numerical modeling in this document will be limited to heat-only modeling and calculations. Only a preliminary assessment of the heat/moisture ventilation effects and modeling method will be performed in this revision. Modeling of moisture effects on heat removal and emplacement drift temperature may be performed in the future

Revision Vodcast Influence on Assessment Scores and Study Processes in Secondary Physics

Science.gov (United States)

Marencik, Joseph J.

A quasi-experimental switching replications design with matched participants was employed to determine the influence of revision vodcasts, or video podcasts, on students' assessment scores and study processes in secondary physics. This study satisfied a need for quantitative results in the area of vodcast influence on students' learning processes. Thirty-eight physics students in an urban Ohio public high school participated in the study. The students in one Physics class were paired with students in another Physics class through the matching characteristics of current student cumulative test score mean and baseline study process as measured by the Study Process Questionnaire (SPQ). Students in both classes were given identical pedagogic treatment and access to traditional revision tools except for the supplemental revision vodcasts given to the experimental group. After students in the experimental group viewed the revision vodcast for a particular topic, the assessment scores of the students in the experimental group were compared to the assessment scores of the control group through the direct-difference, D, test to determine any difference between the assessment score means of each group. The SPQ was given at the beginning of the experiment and after each physics assessment. The direct-difference method was again used to determine any difference between the SPQ deep approach scores of each group. The SPQ was also used to determine any correlative effects between study process and revision vodcast use on students' assessment scores through descriptive statistics and an analysis of variance (ANOVA) test. Analysis indicated that revision vodcast use significantly increased students' assessment scores (p.05). There were no significant correlative effects of revision vodcast use and study processes on students' assessment scores (p>.05). This study offers educators the empirical support to devote the necessary effort, time, and resources into developing successful

Medical Examination of Aliens--Revisions to Medical Screening Process. Final rule.

Science.gov (United States)

2016-01-26

The Centers for Disease Control and Prevention (CDC), within the Department of Health and Human Services (HHS), is issuing this final rule (FR) to amend its regulations governing medical examinations that aliens must undergo before they may be admitted to the United States. Based on public comment received, HHS/CDC did not make changes from the NPRM published on June 23, 2015. Accordingly, this FR will: Revise the definition of communicable disease of public health significance by removing chancroid, granuloma inguinale, and lymphogranuloma venereum as inadmissible health-related conditions for aliens seeking admission to the United States; update the notification of the health-related grounds of inadmissibility to include proof of vaccinations to align with existing requirements established by the Immigration and Nationality Act (INA); revise the definitions and evaluation criteria for mental disorders, drug abuse and drug addiction; clarify and revise the evaluation requirements for tuberculosis; clarify and revise the process for the HHS/CDC-appointed medical review board that convenes to reexamine the determination of a Class A medical condition based on an appeal; and update the titles and designations of federal agencies within the text of the regulation.

Landing Gear Integration in Aircraft Conceptual Design. Revision

Science.gov (United States)

Chai, Sonny T.; Mason, William H.

1997-01-01

The design of the landing gear is one of the more fundamental aspects of aircraft design. The design and integration process encompasses numerous engineering disciplines, e.g., structure, weights, runway design, and economics, and has become extremely sophisticated in the last few decades. Although the design process is well-documented, no attempt has been made until now in the development of a design methodology that can be used within an automated environment. As a result, the process remains to be a key responsibility for the configuration designer and is largely experience-based and graphically-oriented. However, as industry and government try to incorporate multidisciplinary design optimization (MDO) methods in the conceptual design phase, the need for a more systematic procedure has become apparent. The development of an MDO-capable design methodology as described in this work is focused on providing the conceptual designer with tools to help automate the disciplinary analyses, i.e., geometry, kinematics, flotation, and weight. Documented design procedures and analyses were examined to determine their applicability, and to ensure compliance with current practices and regulations. Using the latest information as obtained from industry during initial industry survey, the analyses were in terms modified and expanded to accommodate the design criteria associated with the advanced large subsonic transports. Algorithms were then developed based on the updated analysis procedures to be incorporated into existing MDO codes.

48 CFR 15.307 - Proposal revisions.

Science.gov (United States)

2010-10-01

... AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Source Selection 15.307 Proposal revisions. (a) If an... allow proposal revisions to clarify and document understandings reached during negotiations. At the... submit a final proposal revision. The contracting officer is required to establish a common cut-off date...

Conceptual design report for a remotely operated cask handling system. Revision 1

International Nuclear Information System (INIS)

Yount, J.A.; Berger, J.D.

1984-09-01

Recent advances in remote handling utilizing commercial robotics are conceptually applied to lowering operator cumulative radiation exposure and increasing throughput during cask handling operations in nuclear shipping and receiving facilities. Revision 1 incorporates functional criteria for facility equipment, equipment technical outline specifications, and interface control drawings to assist Architect Engineers in the application of remote handling to waste shipping and receiving facilities. The document has also been updated to show some of the equipment used in proof-of-principle testing during fiscal year 1984. 10 references, 50 figures, 1 table

7 CFR 3015.115 - Budget revisions.

Science.gov (United States)

2010-01-01

... 7 Agriculture 15 2010-01-01 2010-01-01 false Budget revisions. 3015.115 Section 3015.115..., DEPARTMENT OF AGRICULTURE UNIFORM FEDERAL ASSISTANCE REGULATIONS Programmatic Changes and Budget Revisions § 3015.115 Budget revisions. (a) Nonconstruction projects. (1) Except as provided in paragraph (a)(2) of...

Formal Dismissal Procedures Under Illinois Teacher Tenure Laws. Revised Edition.

Science.gov (United States)

Jenkins, Newell N.; And Others

This handbook, an updated and revised version of the 1975 original, contains the new statutory requirements, state board of education rules, and court decisions pertaining to teacher dismissal in Illinois. This handbook is designed to acquaint Illinois school administrators and school board members with the legal procedures necessary in dismissal…

Language Practice with Multimedia Supported Web-Based Grammar Revision Material

Science.gov (United States)

Baturay, Meltem Huri; Daloglu, Aysegul; Yildirim, Soner

2010-01-01

The aim of this study was to investigate the perceptions of elementary-level English language learners towards web-based, multimedia-annotated grammar learning. WEBGRAM, a system designed to provide supplementary web-based grammar revision material, uses audio-visual aids to enrich the contextual presentation of grammar and allows learners to…

A study on scar revision

Directory of Open Access Journals (Sweden)

Ashutosh Talwar

2016-04-01

Full Text Available Introduction: Scars are psychologically distressing for the patients and have an impact on the quality of life and self esteem of the patients. Scar revision is an aesthetic skill which is mastered by plastic surgeons and encroached now by dermatosurgeons. Scars on the face are aesthetically unacceptable and various techniques have been improvised for making a scar aesthetically acceptable. Various types of techniques are used for scar revision like W plasty, Z plasty and VY plasty. Aims: To see the efficacy of various scar revision techniques including Z plasty, VY plasty and W plasty in 30 patients with disfiguring scars. Methods: We selected twenty patients of disfiguring scars for the study. The scars from various causes including trauma and burns were included in our study. Various techniques of scar revision include Z plasty, W plasty and VY plasty were performed according to the type and site of scar. Results: Male: female was 1.5: 1. The scar revision surgery yielded excellent results with minimal complications including haematoma formation, secondary infection and delayed healing seen in 5% patients each. Regarding the efficacy of scar revision, excellent improvement was seen in 60% patients, moderate improvement was seen in 30% patients and mild improvement was seen in 10% patients. Conclusions: Dermatologists can employ a number of surgical scar revision techniques. While some are better suited to treat specific types of scars, they can be used in combination with each other or with adjunctive therapies to achieve optimal results.

Complications Following Primary and Revision Transsphenoidal Surgeries for Pituitary Tumors

Science.gov (United States)

Krings, James G.; Kallogjeri, Dorina; Wineland, Andre; Nepple, Kenneth G.; Piccirillo, Jay F.; Getz, Anne E.

2014-01-01

Objective This study aimed to determine the incidence of major complications following both primary and revision transsphenoidal pituitary surgery. Major complications included endocrinopathic, skull base, orbital, hemorrhagic and thromboembolic complications, respiratory failure, and death. Secondarily, this study aimed to examine factors associated with the occurrence of complications. Study Design Retrospective cohort analysis of California and Florida all-payer databases from 2005-2008. Methods The major complication rate following both primary and revision transsphenoidal pituitary surgery was calculated. Bivariate analyses were performed to investigate the relationship of patient characteristics with complication occurrence, and a multivariate model was constructed to determine risk factors associated with these complications. Results 5,277 primary cases and 192 revision cases met inclusion criteria. There was a non-significant absolute difference of 3.09% (95% CI −11.00 to 16.14) between the rate of complications following primary (n=443; 8.39%) and revision (n=22; 11.46%) surgeries. Multivariate analyses showed that patients with Medicare (OR=1.74; 95% CI 1.17 to 2.61), Medicaid (OR=2.13; 95% CI 1.59 to 2.86), or a malignant neoplasm (OR=3.10; 95% CI 1.62 to 5.93) were more likely to have complications. Conclusions The rate of major complications following transsphenoidal pituitary surgery is lower than earlier retrospective reports. The overall complication rate following revision surgery was not significantly different from primary surgery. Insurance status and a diagnosis of a malignant neoplasm were associated with a higher rate of complications. PMID:25263939

Updated and revised neutron reaction data for 237Np

Directory of Open Access Journals (Sweden)

Chen Guochang

2017-01-01

Full Text Available Nuclear data with high accuracy for minor actinides play an important role in nuclear technology applications, including reactor design and operation, fuel cycle, estimation of the amount of minor actinides in high burn-up reactors and the minor actinides transmutation. Based on the evaluated experimental data, the updated and revised evaluation of a full set of n+237Np nuclear data from 10−5 eV ∼ 20 MeV are carried out and recommended. Mainly revised quantities are neutron multiplicities from fission reaction, inelastic, fission, (n, 2n and (n, γ reaction cross sections as well as angular distribution and so on. The promising results are obtained when the renewal evaluated data of 237Np will be used to instead of the evaluated data in CENDL-3.1 database.

Revised Severe Accident Research Program plan, FY 1990--1992

International Nuclear Information System (INIS)

1989-08-01

For the past 10 years, since the Three Mile Island accident, the NRC has sponsored an active research program on light-water-reactor severe accidents as part of a multi-faceted approach to reactor safety. This report describes the revised Severe Accident Research Program (SARP) and how the revisions are designed to provide confirmatory information and technical support to the NRC staff in implementing the staff's Integration Plan for Closure of Severe Accident Issues as described in SECY-88-147. The revised SARP addresses both the near-term research directed at providing a technical basis upon which decisions on important containment performance issues can be made and the long-term research needed to confirm and refine our understanding of severe accidents. In developing this plan, the staff recognized that the overall goal is to reduce the uncertainties in the source term sufficiently to enable the staff to make regulatory decisions on severe accident issues. However, the staff also recognized that for some issues it may not be practical to attempt to further reduce uncertainties, and some regulatory decisions or conclusions will have to be made with full awareness of existing uncertainties. 2 figs., 1 tab

Ventriculoperitoneal shunt complications needing shunt revision in children: A review of 5 years of experience with 48 revisions

Directory of Open Access Journals (Sweden)

Rajendra K Ghritlaharey

2012-01-01

Full Text Available Background: The aim of this study was to review the management of ventriculoperitoneal (VP shunt complications in children. Patients and Methods: During the last 5 years (January 1, 2006 to December 31, 2010, 236 VP shunt operations were performed in children under 12 years of age; of these, 40 (16.94% developed shunt complications and those who underwent VP shunt revisions were studied. Results: This prospective study included 40 (28 boys and 12 girls children and required 48 shunt revisions. Complications following VP shunts that required shunt revisions were peritoneal catheter/peritoneal end malfunction (18, shunt/shunt tract infections (7, extrusion of peritoneal catheter through anus (5, ventricular catheter malfunction (4, cerebrospinal fluid (CSF leak from abdominal wound (4, shunt system failure (2, ventricular end/shunt displacement (2, CSF pseudocysts peritoneal cavity (2, extrusion of peritoneal catheter from neck, chest, abdominal scar and through umbilicus, one each. Four-fifth of these shunt complications occurred within 6 months of previous surgery. Surgical procedures done during shunt revisions in order of frequency were revision of peritoneal part of shunt (27, 56.25%, revision of entire shunt system (6, 12.5%, extra ventricular drainage and delayed re-shunt (5, 10.41%, shunt removal and delayed re-shunt (5, 10.41%, opposite side shunting (2, 4.16%, cysts excision and revision of peritoneal catheter (2, 4.16% and revision of ventricular catheter (1, 2.08%. The mortalities following VP shunt operations were 44 (18.64% and following shunt revisions were 4 (10%. Conclusions: VP shunt done for hydrocephalus in children is not only prone for complications and need for revision surgery but also associated with considerable mortality.

Sequencing of the Chlamydophila psittaci ompA Gene Reveals a New Genotype, E/B, and the Need for a Rapid Discriminatory Genotyping Method

Science.gov (United States)

Geens, Tom; Desplanques, Ann; Van Loock, Marnix; Bönner, Brigitte M.; Kaleta, Erhard F.; Magnino, Simone; Andersen, Arthur A.; Everett, Karin D. E.; Vanrompay, Daisy

2005-01-01

Twenty-one avian Chlamydophila psittaci isolates from different European countries were characterized using ompA restriction fragment length polymorphism, ompA sequencing, and major outer membrane protein serotyping. Results reveal the presence of a new genotype, E/B, in several European countries and stress the need for a discriminatory rapid genotyping method. PMID:15872282

Cochlear implant revision surgeries in children.

Science.gov (United States)

Amaral, Maria Stella Arantes do; Reis, Ana Cláudia Mirândola B; Massuda, Eduardo T; Hyppolito, Miguel Angelo

2018-02-16

The surgery during which the cochlear implant internal device is implanted is not entirely free of risks and may produce problems that will require revision surgeries. To verify the indications for cochlear implantation revision surgery for the cochlear implant internal device, its effectiveness and its correlation with certain variables related to language and hearing. A retrospective study of patients under 18 years submitted to cochlear implant Surgery from 2004 to 2015 in a public hospital in Brazil. Data collected were: age at the time of implantation, gender, etiology of the hearing loss, audiological and oral language characteristics of each patient before and after Cochlear Implant surgery and any need for surgical revision and the reason for it. Two hundred and sixty-five surgeries were performed in 236 patients. Eight patients received a bilateral cochlear implant and 10 patients required revision surgery. Thirty-two surgeries were necessary for these 10 children (1 bilateral cochlear implant), of which 21 were revision surgeries. In 2 children, cochlear implant removal was necessary, without reimplantation, one with cochlear malformation due to incomplete partition type I and another due to trauma. With respect to the cause for revision surgery, of the 8 children who were successfully reimplanted, four had cochlear calcification following meningitis, one followed trauma, one exhibited a facial nerve malformation, one experienced a failure of the cochlear implant internal device and one revision surgery was necessary because the electrode was twisted. The incidence of the cochlear implant revision surgery was 4.23%. The period following the revision surgeries revealed an improvement in the subject's hearing and language performance, indicating that these surgeries are valid in most cases. Copyright © 2018 Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial. Published by Elsevier Editora Ltda. All rights reserved.

Are revised models better models? A skill score assessment of regional interannual variability

Science.gov (United States)

Sperber, Kenneth R.; Participating AMIP Modelling Groups

1999-05-01

Various skill scores are used to assess the performance of revised models relative to their original configurations. The interannual variability of all-India, Sahel and Nordeste rainfall and summer monsoon windshear is examined in integrations performed under the experimental design of the Atmospheric Model Intercomparison Project. For the indices considered, the revised models exhibit greater fidelity at simulating the observed interannual variability. Interannual variability of all-India rainfall is better simulated by models that have a more realistic rainfall climatology in the vicinity of India, indicating the beneficial effect of reducing systematic model error.

Salt Repository Project shaft design guide: Revision 0

International Nuclear Information System (INIS)

1987-12-01

The Salt Repository Project (SRP) Shaft Design Guide (SDG) and the accompanying SRP Input to Seismic Design define the basic approach for developing appropriate shaft designs for a high-level nuclear waste repository in salt at a proposed site in Deaf Smith County, Texas. The SDG is based on current mining industry standards and practices enhanced to meet the special needs of an underground nuclear waste repository. It provides a common approach for design of both the exploratory and repository shafts. The SDG defines shaft lining and material concepts and presents methods for calculating the loads and displacements that will be imposed on lining structures. It also presents the methodology and formulae for sizing lining components. The SDG directs the shaft designer to sources of geoscience and seismic design data for the Deaf Smith County, Texas repository site. In addition, the SDG describes methods for confirming shaft lining design by means of computer analysis, and it discusses performance monitoring needs that must be considered in the design. 113 refs., 18 figs., 14 tabs

The Design of a Navigator for a Testbed Autonomous Underwater Vehicle

Science.gov (United States)

1989-12-01

AD-A231 733 NAVAL POSTGRADUATE SCHOOL Monterey, California DTC C ’S B’- i I A VDI ELECTE 1i EB 0 6 991| D THESIS E THE DESIGN OF A NAVIGATOR FOR A...255,255,0); /* yellow (512-1023) * for (i= 1024; i< 2048 ; ++i) mapcolor(i,255 ,0,255); 1* magenta (1024-2047 )*/ color(BLACK); clearo; swapbufferso; 1

An ebCMOS camera system for marine bioluminescence observation: The LuSEApher prototype

Energy Technology Data Exchange (ETDEWEB)

Dominjon, A., E-mail: a.dominjon@ipnl.in2p3.fr [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Ageron, M. [CNRS/IN2P3, Centre de Physique des Particules de Marseille, Marseille, F-13288 (France); Barbier, R. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Universite de Lyon, Universite Lyon 1, Lyon F-69003 (France); Billault, M.; Brunner, J. [CNRS/IN2P3, Centre de Physique des Particules de Marseille, Marseille, F-13288 (France); Cajgfinger, T. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Universite de Lyon, Universite Lyon 1, Lyon F-69003 (France); Calabria, P. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Chabanat, E. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France); Universite de Lyon, Universite Lyon 1, Lyon F-69003 (France); Chaize, D.; Doan, Q.T.; Guerin, C.; Houles, J.; Vagneron, L. [CNRS/IN2P3, Institut de Physique Nucleaire de Lyon, Villeurbanne F-69622 (France)

2012-12-11

The ebCMOS camera, called LuSEApher, is a marine bioluminescence recorder device adapted to extreme low light level. This prototype is based on the skeleton of the LUSIPHER camera system originally developed for fluorescence imaging. It has been installed at 2500 m depth off the Mediterranean shore on the site of the ANTARES neutrino telescope. The LuSEApher camera is mounted on the Instrumented Interface Module connected to the ANTARES network for environmental science purposes (European Seas Observatory Network). The LuSEApher is a self-triggered photo detection system with photon counting ability. The presentation of the device is given and its performances such as the single photon reconstruction, noise performances and trigger strategy are presented. The first recorded movies of bioluminescence are analyzed. To our knowledge, those types of events have never been obtained with such a sensitivity and such a frame rate. We believe that this camera concept could open a new window on bioluminescence studies in the deep sea.

Revised STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA): extending the CONSORT statement

Science.gov (United States)

MacPherson, Hugh; Altman, Douglas G; Hammerschlag, Richard; Li, Youping; Wu, Taixiang; White, Adrian; Moher, David

2010-01-01

The STandards for Reporting Interventions in Clinical Trials of Acupuncture (STRICTA) were published in five journals in 2001 and 2002. These guidelines, in the form of a checklist and explanations for use by authors and journal editors, were designed to improve reporting of acupuncture trials, particularly the interventions, thereby facilitating their interpretation and replication. Subsequent reviews of the application and impact of STRICTA have highlighted the value of STRICTA as well as scope for improvements and revision. To manage the revision process a collaboration between the STRICTA Group, the CONSORT Group and the Chinese Cochrane Centre was developed in 2008. An expert panel with 47 participants was convened that provided electronic feedback on a revised draft of the checklist. At a subsequent face-to-face meeting in Freiburg, a group of 21 participants further revised the STRICTA checklist and planned dissemination. The new STRICTA checklist, which is an official extension of CONSORT, includes 6 items and 17 subitems. These set out reporting guidelines for the acupuncture rationale, the details of needling, the treatment regimen, other components of treatment, the practitioner background and the control or comparator interventions. In addition, and as part of this revision process, the explanations for each item have been elaborated, and examples of good reporting for each item are provided. In addition, the word ‘controlled’ in STRICTA is replaced by ‘clinical’, to indicate that STRICTA is applicable to a broad range of clinical evaluation designs, including uncontrolled outcome studies and case reports. It is intended that the revised STRICTA checklist, in conjunction with both the main CONSORT statement and extension for non-pharmacological treatment, will raise the quality of reporting of clinical trials of acupuncture. PMID:20615861

24 CFR 968.225 - Budget revisions.

Science.gov (United States)

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Budget revisions. 968.225 Section... Fewer Than 250 Units) § 968.225 Budget revisions. (a) A PHA shall not incur any modernization cost in excess of the total HUD-approved CIAP budget. A PHA shall submit a budget revision, in a form prescribed...

The TT, TB, EB and BB correlations in anisotropic inflation

Energy Technology Data Exchange (ETDEWEB)

Chen, Xingang [Department of Physics, The University of Texas at Dallas, Richardson, TX 75083 (United States); Emami, Razieh [School of Physics, Institute for Research in Fundamental Sciences (IPM), P. O. Box 19395-5531, Tehran (Iran, Islamic Republic of); Firouzjahi, Hassan [School of Astronomy, Institute for Research in Fundamental Sciences (IPM), P. O. Box 19395-5531, Tehran (Iran, Islamic Republic of); Wang, Yi, E-mail: Xingang.Chen@utdallas.edu, E-mail: emami@ipm.ir, E-mail: firouz@ipm.ir, E-mail: yw366@cam.ac.uk [Centre for Theoretical Cosmology, DAMTP, University of Cambridge, Cambridge CB3 0WA (United Kingdom)

2014-08-01

The ongoing and future experiments will measure the B-mode from different sky coverage and frequency bands, with the potential to reveal non-trivial features in polarization map. In this work we study the TT, TB, EB and BB correlations associated with the B-mode polarization of CMB map in models of charged anisotropic inflation. The model contains a chaotic-type large field complex inflaton which is charged under the U(1) gauge field. We calculate the statistical anisotropies generated in the power spectra of the curvature perturbation, the tensor perturbation and their cross-correlation. It is shown that the asymmetry in tensor power spectrum is a very sensitive probe of the gauge coupling. While the level of statistical anisotropy in temperature power spectrum can be small and satisfy the observational bounds, the interactions from the gauge coupling can induce large directional dependence in tensor modes. This will leave interesting anisotropic fingerprints in various correlations involving the B-mode polarization such as the TB cross-correlation which may be detected in upcoming Planck polarization data. In addition, the TT correlation receives an anisotropic contribution from the tensor sector which naturally decays after l ∼> 100. We expect that the mechanism of using tensor sector to induce asymmetry at low l to be generic which can also be applied to address other low l CMB anomalies.

Working Paper for the Revision of San Francisco's Cable Franchise.

Science.gov (United States)

San Francisco Public Library, CA. Video Task Force.

Ideas are presented for the revision of San Francisco's cable franchise. The recommendations in the report are based upon national research of library and urban use of cable communications and are designed to help the city's present and future cable franchises to comply with the regulations of the Federal Communications Commission by March 31,…

Landscapes of Practice: Bricolage as a Method for Situated Design

DEFF Research Database (Denmark)

Büscher, Monica; Gill, Satinder; Mogensen, Preben Holst

2001-01-01

This paper proposes a ‘bricolage’ approach to designing systems for cooperative work. This involves users, participatory designers and ethnographers in a continuing cycle of design and revised work practice, often in settings where resources are limited and short-termresults are required. If expl......This paper proposes a ‘bricolage’ approach to designing systems for cooperative work. This involves users, participatory designers and ethnographers in a continuing cycle of design and revised work practice, often in settings where resources are limited and short-termresults are required...

Effect of graft choice on the outcome of revision anterior cruciate ligament reconstruction in the Multicenter ACL Revision Study (MARS) Cohort

Science.gov (United States)

Wright, Rick W.; Huston, Laura J.; Haas, Amanda K.; Spindler, Kurt P.; Nwosu, Sam K.; Allen, Christina R.; Anderson, Allen F.; Cooper, Daniel E.; DeBerardino, Thomas M.; Dunn, Warren R.; Lantz, Brett (Brick) A.; Stuart, Michael J.; Garofoli, Elizabeth A.; Albright, John P.; Amendola, Annunziato (Ned); Andrish, Jack T.; Annunziata, Christopher C.; Arciero, Robert A.; Bach, Bernard R.; Baker, Champ L.; Bartolozzi, Arthur R.; Baumgarten, Keith M.; Bechler, Jeffery R.; Berg, Jeffrey H.; Bernas, Geoffrey A.; Brockmeier, Stephen F.; Brophy, Robert H.; Bush-Joseph, Charles A.; Butler, J. Brad; Campbell, John D.; Carey, James L.; Carpenter, James E.; Cole, Brian J.; Cooper, Jonathan M.; Cox, Charles L.; Creighton, R. Alexander; Dahm, Diane L.; David, Tal S.; Flanigan, David C.; Frederick, Robert W.; Ganley, Theodore J.; Gatt, Charles J.; Gecha, Steven R.; Giffin, James Robert; Hame, Sharon L.; Hannafin, Jo A.; Harner, Christopher D.; Harris, Norman Lindsay; Hechtman, Keith S.; Hershman, Elliott B.; Hoellrich, Rudolf G.; Hosea, Timothy M.; Johnson, David C.; Johnson, Timothy S.; Jones, Morgan H.; Kaeding, Christopher C.; Kamath, Ganesh V.; Klootwyk, Thomas E.; Levy, Bruce A.; Ma, C. Benjamin; Maiers, G. Peter; Marx, Robert G.; Matava, Matthew J.; Mathien, Gregory M.; McAllister, David R.; McCarty, Eric C.; McCormack, Robert G.; Miller, Bruce S.; Nissen, Carl W.; O'Neill, Daniel F.; Owens, Brett D.; Parker, Richard D.; Purnell, Mark L.; Ramappa, Arun J.; Rauh, Michael A.; Rettig, Arthur C.; Sekiya, Jon K.; Shea, Kevin G.; Sherman, Orrin H.; Slauterbeck, James R.; Smith, Matthew V.; Spang, Jeffrey T.; Svoboda, Steven J.; Taft, Timothy N.; Tenuta, Joachim J.; Tingstad, Edwin M.; Vidal, Armando F.; Viskontas, Darius G.; White, Richard A.; Williams, James S.; Wolcott, Michelle L.; Wolf, Brian R.; York, James J.

2015-01-01

Background Most surgeons believe that graft choice for ACL reconstruction is an important factor related to outcome. Although graft choice may be limited in the revision setting based on previously used grafts, it is still felt to be important. Hypothesis The purpose of this study was to determine if revision ACL graft choice predicts outcomes related to sports function, activity level, OA symptoms, graft re-rupture, and reoperation at two years following revision reconstruction. We hypothesized that autograft use would result in increased sports function, increased activity level, and decreased OA symptoms (as measured by validated patient reported outcome instruments). Additionally, we hypothesized that autograft use would result in decreased graft failure and reoperation rate 2 years following revision ACL reconstruction. Study Design Prospective cohort study; Level of evidence, 2. Methods Revision ACL reconstruction patients were identified and prospectively enrolled by 83 surgeons over 52 sites. Data collected included baseline demographics, surgical technique and pathology, and a series of validated patient reported outcome instruments (IKDC, KOOS, WOMAC, and Marx activity rating score). Patients were followed up at 2 years, and asked to complete the identical set of outcome instruments. Incidence of additional surgery and reoperation due to graft failure were also recorded. Multivariate regression models were used to determine the predictors (risk factors) of IKDC, KOOS, WOMAC, Marx scores, graft re-rupture, and reoperation rate at 2 years following revision surgery. Results 1205 patients were successfully enrolled with 697 (58%) males. Median age was 26. In 88% this was their first revision. 341 (28%) were undergoing revision by the surgeon that had performed the previous reconstruction. 583 (48%) underwent revision reconstruction utilizing an autograft, 590 (49%) allograft, and 32 (3%) both autograft and allograft. Median time since their last ACL

Highly efficient simultaneous ultrasonic assisted adsorption of brilliant green and eosin B onto ZnS nanoparticles loaded activated carbon: Artificial neural network modeling and central composite design optimization

Science.gov (United States)

Jamshidi, M.; Ghaedi, M.; Dashtian, K.; Ghaedi, A. M.; Hajati, S.; Goudarzi, A.; Alipanahpour, E.

2016-01-01

In this work, central composite design (CCD) combined with response surface methodology (RSM) and desirability function approach (DFA) gives useful information about operational condition and also to obtain useful information about interaction and main effect of variables concerned to simultaneous ultrasound-assisted removal of brilliant green (BG) and eosin B (EB) by zinc sulfide nanoparticles loaded on activated carbon (ZnS-NPs-AC). Spectra overlap between BG and EB dyes was extensively reduced and/or omitted by derivative spectrophotometric method, while multi-layer artificial neural network (ML-ANN) model learned with Levenberg-Marquardt (LM) algorithm was used for building up a predictive model and prediction of the BG and EB removal. The ANN efficiently was able to forecast the simultaneous BG and EB removal that was confirmed by reasonable numerical value i.e. MSE of 0.0021 and R2 of 0.9589 and MSE of 0.0022 and R2 of 0.9455 for testing data set, respectively. The results reveal acceptable agreement among experimental data and ANN predicted results. Langmuir as the best model for fitting experimental data relevant to BG and EB removal indicates high, economic and profitable adsorption capacity (258.7 and 222.2 mg g- 1) that supports and confirms its applicability for wastewater treatment.

CUSTOM TRIFLANGE ACETABULAR COMPONENTS IN REVISION HIP REPLACEMENT (EXPERIENCE REVIEW

Directory of Open Access Journals (Sweden)

A. A. Korytkin

2017-01-01

Full Text Available Extensive defects of acetabulum especially accompanied by pelvis discontinuity at the level of acetabulum pose a serious challenge in revision hip replacement and create additional complexity in fixing the acetabular component. One of the perspective options to solve the above issue is the use of custom triflange acetabular components (CTAC designed based on preoperative computer tomography given the specifics of bone defects of the patient. Purpose of the study — to evaluate the outcomes of CTAC use in revision hip replacement.Materials and methods. The authors analyzed treatment outcomes of 12 patients after revision hip replacement using additive techniques of computer simulation and 3D printing CTAC. Follow up period after the surgery averaged 7±3 months (from one to ten months. 7 out of 12 patients had acetabular defects of Paprosky 3B type, 4 patients had defects of Paprosky 3A and in one patient — of Paprosky 2C.Results. Two out of twelve patients had prosthesis dislocations that required revision hip surgery, one of those patients underwent open reduction of dislocation with wound debridement, another patient underwent replacement of articulating couple of acetabular component. Total scores under Harris Hip Score and paint VAS score prior to treatment was 28±7 and 7±1 points respectively, postoperative scores were 76±9 and 3±1 respectively.Conclusion. The application of additive techniques for revision hip replacement in patients with extensive acetabular and pelvic defects allows to make a precise preoperative planning, to restore joint rotation center, to reconstruct bone defects and to securely fix triflange acetabular component that altogether significantly improve treatment outcomes and patients satisfaction with the surgery.

Students’ Perception toward the Implementation of Peer-Assessment in Writing; Before and After Revision

Directory of Open Access Journals (Sweden)

Husni Mubarok

2017-10-01

Full Text Available This study was aimed at elaborating students’ perception toward the implementation of peer assessment in writing class either before or after revision. Writing becomes one of skills which should be mastered by students in order to get higher level of literacy. Writing is a productive skill which asks students to arrange words and organize them into good writing which could be understood by readers. The success of writing is determined by the writing process itself starting from planning, first draft writing, revising, and editing. One of the strategies used in teaching writing is by implementing peer assessment. Peer assessment strategy becomes one of important parts in the process of writing because there will be feedback or suggestion from peers in doing a review. The number of the subject of this research was students in second semester of the English Education Department of UNISNU Jepara. This research was conducted on even semester. The total number of the students, which became respondents, was 37 students of English Education Department. The research design used was qualitative research which measured students’ perceptions of the implementation of peer assessment in writing: before and after revision. The result showed that before revision, students had negative perception toward their own writing. After revision, they had positive perceptions toward peer assessment strategy. Those included usefulness and meaningfulness, nature of feedback, reality of feedback, precision, validity, fairness, and personal goal-setting. Besides that, the score after revision (7.9 was higher than the score before revision (6.62. It meant that the result showed the increasing of students’ score after revision.

Design parameters and source terms: Volume 1, Design parameters: Revision 0

International Nuclear Information System (INIS)

1987-10-01

The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report by Stearns Catalytic Corporation (SCC), entitled ''Design Parameters and Source Terms for a Two-Phase Repository in Salt,'' 1985, to the level of the Site Characterization Plan - Conceptual Design Report. The previous unpublished SCC Study identifies the data needs for the Environmental Assessment effort for seven possible Salt Repository sites

Analysis of VIA and EbA in a River Bank Erosion Prone Area of Bangladesh Applying DPSIR Framework

Directory of Open Access Journals (Sweden)

Syed Hafizur Rahman

2016-10-01

Full Text Available This study aims to set up a comprehensive approach to the Vulnerability and Impact Assessment (VIA of river erosion and to suggest Ecosystem-based Adaptation (EbA practices. Based on the analysis of vulnerability using the Driver-Pressure-State-Impact-Response (DPSIR framework, this paper discusses some of the significant climatic (rainfall pattern, temperature, seasonal drift, cold wave and heat wave and non-climatic (river erosion, repetitive death of field crops and agrochemicals forces in the Kazipur Upazila (Sirajganj District—a river erosion-prone area of Bangladesh. Both primary (Key Informants Interview, Household Survey, and Focus Group Discussion and secondary (climatic, literature review data have been used in revealing the scenario of climatic stress. The analysis revealed a slightly increasing trend of mean annual temperature, and a decreasing trend of total annual rainfall from 1981 to 2015, which have been supported by people’s perception. This study found that river erosion, the increase of temperature and the late arrival of monsoon rain, excessive monsoon rainfall, high use of agrochemicals, and flow alterations are major drivers in the riverine ecosystem. These drivers are creating pressures on agricultural land, soil fertility, water availability and livelihood patterns of affected communities. Hence, floating bed cultivation, integrated pest management, use of cover crops, reforestation, the introduction of an agro-weather forecasting system, and a new variety of flood tolerant species have been suggested as potential EbA to cope with river bank erosion and to increase the capacity of the affected ecosystem.

Database modeling and design logical design

CERN Document Server

Teorey, Toby J; Nadeau, Tom; Jagadish, HV

2011-01-01

Database systems and database design technology have undergone significant evolution in recent years. The relational data model and relational database systems dominate business applications; in turn, they are extended by other technologies like data warehousing, OLAP, and data mining. How do you model and design your database application in consideration of new technology or new business needs? In the extensively revised fifth edition, you'll get clear explanations, lots of terrific examples and an illustrative case, and the really practical advice you have come to count on--with design rules

Database modeling and design logical design

CERN Document Server

Teorey, Toby J; Nadeau, Tom; Jagadish, HV

2005-01-01

Database systems and database design technology have undergone significant evolution in recent years. The relational data model and relational database systems dominate business applications; in turn, they are extended by other technologies like data warehousing, OLAP, and data mining. How do you model and design your database application in consideration of new technology or new business needs? In the extensively revised fourth edition, you'll get clear explanations, lots of terrific examples and an illustrative case, and the really practical advice you have come to count on--with design rul

S. pombe CLASP needs dynein, not EB1 or CLIP170, to induce microtubule instability and slows polymerization rates at cell tips in a dynein-dependent manner

Science.gov (United States)

Grallert, Agnes; Beuter, Christoph; Craven, Rachel A.; Bagley, Steve; Wilks, Deepti; Fleig, Ursula; Hagan, Iain M.

2006-01-01

The Schizosaccharomyces pombe CLIP170-associated protein (CLASP) Peg1 was identified in a screen for mutants with spindle formation defects and a screen for molecules that antagonized EB1 function. The conditional peg1.1 mutant enabled us to identify key features of Peg1 function. First, Peg1 was required to form a spindle and astral microtubules, yet destabilized interphase microtubules. Second, Peg1 was required to slow the polymerization rate of interphase microtubules that establish end-on contact with the cortex at cell tips. Third, Peg1 antagonized the action of S. pombe CLIP170 (Tip1) and EB1 (Mal3). Fourth, although Peg1 resembled higher eukaryotic CLASPs by physically associating with both Mal3 and Tip1, neither Tip1 nor Mal3 was required for Peg1 to destabilize interphase microtubules or for it to associate with microtubules. Conversely, neither Mal3 nor Tip1 required Peg1 to associate with microtubules or cell tips. Consistently, while mal3.Δ and tip1.Δ disrupted linear growth, corrupting peg1 + did not. Fifth, peg1.1 phenotypes resembled those arising from deletion of the single heavy or both light chains of fission yeast dynein. Furthermore, all interphase phenotypes arising from peg1 + manipulation relied on dynein function. Thus, the impact of S. pombe CLASP on interphase microtubule behavior is more closely aligned to dynein than EB1 or CLIP170. PMID:16951255

Revised National Pressure Ulcer Advisory Panel Pressure Injury Staging System: Revised Pressure Injury Staging System.

Science.gov (United States)

Edsberg, Laura E; Black, Joyce M; Goldberg, Margaret; McNichol, Laurie; Moore, Lynn; Sieggreen, Mary

Our understanding of pressure injury etiology and development has grown in recent years through research, clinical expertise, and global interdisciplinary expert collaboration. Therefore, the National Pressure Ulcer Advisory Panel (NPUAP) has revised the definition and stages of pressure injury. The revision was undertaken to incorporate the current understanding of the etiology of pressure injuries, as well as to clarify the anatomical features present or absent in each stage of injury. An NPUAP-appointed Task Force reviewed the literature and created drafts of definitions, which were then reviewed by stakeholders and the public, including clinicians, educators, and researchers around the world. Using a consensus-building methodology, these revised definitions were the focus of a multidisciplinary consensus conference held in April 2016. As a result of stakeholder and public input, along with the consensus conference, important changes were made and incorporated into the new staging definitions. The revised staging system uses the term injury instead of ulcer and denotes stages using Arabic numerals rather than Roman numerals. The revised definition of a pressure injury now describes the injuries as usually occurring over a bony prominence or under a medical or other device. The revised definition of a Stage 2 pressure injury seeks to clarify the difference between moisture-associated skin damage and injury caused by pressure and/or shear. The term suspected has been removed from the Deep Tissue Pressure Injury diagnostic label. Each definition now describes the extent of tissue loss present and the anatomical features that may or may not be present in the stage of injury. These important revisions reflect the methodical and collaborative approach used to examine the available evidence and incorporate current interdisciplinary clinical expertise into better defining the important phenomenon of pressure injury etiology and development.

Individual questions of financial control and revision

Directory of Open Access Journals (Sweden)

В. М. Глібко

2015-05-01

Full Text Available Problem setting. In modern conditions at investigation and gathering of proofs in criminal proceedings according to item 93 CPC of Ukraine collecting of proofs which is carried out by the criminal proceedings parties, victim is important, the representative of the legal person, in which relation carries out manufacture, including a way истребования and receptions from public authorities, local governments, the enterprises, establishments and organisations, official and physical persons of things, documents, data, conclusions of experts, conclusions of revisions and certificates of checks. Recent research and publications analisis. In scientific sources questions of carrying out of revisions S. B.Zhivko, V.V.Akimov, G.Demjanchuk, J.Buzdugan is considered. Paper objective. Article purpose is studying and definition of a place of revision among forms of inspection of the state control and use of results of revision in criminal proceedings. Paper main body. Off-schedule exit revision that is revision which is not provided in plans of work of body of the state financial control is considered and is spent at presence at least one of the circumstances listed in item 11 of the Law of Ukraine «About main principles of realisation of the state financial control in Ukraine». If revision is carried out on request of investigating bodies it is spent on the basis of the petition of the inspector and accepted by the results of consideration of this petition of the decision of the investigatory judge. The primary goal of revision on request of investigating bodies or on the basis of court definition is reception of proofs on business. Therefore the revision certificate admits the written proof as on the basis of its conclusion of the inspector, the public prosecutor receives the information on a perfect crime, abusing, and also on the persons who have committed a crime, on the period of commission of crime and an amount of damage. In criminal

Outcome, revision rate and indication for revision following resurfacing hemiarthroplasty for osteoarthritis of the shoulder

DEFF Research Database (Denmark)

Rasmussen, J V; Polk, A; Sorensen, A K

2014-01-01

In this study, we evaluated patient-reported outcomes, the rate of revision and the indications for revision following resurfacing hemiarthroplasty of the shoulder in patients with osteoarthritis. All patients with osteoarthritis who underwent primary resurfacing hemiarthroplasty and reported...... to the Danish Shoulder Arthroplasty Registry (DSR), between January 2006 and December 2010 were included. There were 772 patients (837 arthroplasties) in the study. The Western Ontario Osteoarthritis of the Shoulder (WOOS) index was used to evaluate patient-reported outcome 12 months (10 to 14) post......-operatively. The rates of revision were calculated from the revisions reported to the DSR up to December 2011 and by checking deaths with the Danish National Register of Persons. A complete questionnaire was returned by 688 patients (82.2%). The mean WOOS was 67 (0 to 100). A total of 63 hemiarthroplasties (7...

Three Principles to REVISE People's Unethical Behavior.

Science.gov (United States)

Ayal, Shahar; Gino, Francesca; Barkan, Rachel; Ariely, Dan

2015-11-01

Dishonesty and unethical behavior are widespread in the public and private sectors and cause immense annual losses. For instance, estimates of U.S. annual losses indicate $1 trillion paid in bribes, $270 billion lost due to unreported income, and $42 billion lost in retail due to shoplifting and employee theft. In this article, we draw on insights from the growing fields of moral psychology and behavioral ethics to present a three-principle framework we call REVISE. This framework classifies forces that affect dishonesty into three main categories and then redirects those forces to encourage moral behavior. The first principle, reminding, emphasizes the effectiveness of subtle cues that increase the salience of morality and decrease people's ability to justify dishonesty. The second principle, visibility, aims to restrict anonymity, prompt peer monitoring, and elicit responsible norms. The third principle, self-engagement, increases people's motivation to maintain a positive self-perception as a moral person and helps bridge the gap between moral values and actual behavior. The REVISE framework can guide the design of policy interventions to defeat dishonesty. © The Author(s) 2015.

Mixed Waste Management Facility, revised FY94 Plan

International Nuclear Information System (INIS)

Streit, R.

1994-01-01

This revision of the FY94 Plan incorporates changes to work during FY94 in response to the DOE request in the DOE KD-1 decision letter of June 28,1994. This letter provided guidance of both scope and budget profile in response to the Conceptual Design Report (CDR) issued by the MWMF Project in April, 1994. This work plan only addresses work for the remainder of FY94. A revised plan for the complete project is in development and will be issued separately. Since February, 1994, the MWMF Project has been operating on DOE guidance directing that work on the CDR be completed, that only other essential work be continued to maintain the project, and that costs be maintained at approximately the January, 1994 spending levels until a KD-1 decision was made. This has formed the basis for monthly reports through June, 1994. The baseline contained in this report will become the basis for reports during the remainder of FY94

Circumcision revision in male children

Directory of Open Access Journals (Sweden)

Mohammed A. Al-Ghazo

2006-08-01

Full Text Available OBJECTIVE: To determine indications for circumcision revision and to identify the specialty of the person who performed unsatisfactory primary circumcision. MATERIALS AND METHODS: The authors reviewed medical records of 52 cases that underwent circumcision revision over a 6-year period (1998 to 2004. Sleeve surgical technique was used for revision in patients with redundant foreskin or concealed penis, penoplasty for partial or complete degloving of the penis and meatotomy for external meatal stenosis. The mean age of children was 32 months (range 6 months to 9 years. RESULTS: Most of unsatisfactory primary circumcisions (86.7% were performed by laymen. All patients who underwent circumcision revision had good to excellent cosmetic results. CONCLUSION: Primary circumcision performed by laymen carry a high complication rate and serious complications may occur. A period of training and direct supervision by physicians is required before allowing laymen to perform circumcision independently.

Comparison of orthogonal kilovolt X-ray images and cone-beam CT matching results in setup error assessment and correction for EB-PBI during free breathing

International Nuclear Information System (INIS)

Wang Wei; Li Jianbin; Hu Hongguang; Ma Zhifang; Xu Min; Fan Tingyong; Shao Qian; Ding Yun

2014-01-01

Objective: To compare the differences in setup error (SE) assessment and correction between the orthogonal kilovolt X-ray images and CBCT in EB-PBI patients during free breathing. Methods: Nineteen patients after breast conserving surgery EB-PBI were recruited. Interfraction SE was acquired using orthogonal kilovolt X-ray setup images and CBCT, after on-line setup correction,calculate the residual error and compare the SE, residual error and setup margin (SM) quantified for orthogonal kilovolt X-ray images and CBCT. Wilcoxon sign-rank test was used to evaluate the differences. Results: The CBCT based SE (systematic error, ∑) was smaller than the orthogonal kilovolt X-ray images based ∑ in AP direction (-1.2 mm vs 2.00 mm; P=0.005), and there was no statistically significant differences for three dimensional directions in random error (σ) (P=0.948, 0.376, 0.314). After on-line setup correction,CBCT decreases setup residual error than the orthogonal kilovolt X-ray images in AP direction (Σ: -0.20 mm vs 0.50 mm, P=0.008; σ: 0.45 mm vs 1.34 mm, P=0.002). And also the CBCT based SM was smaller than orthogonal kilovolt X-ray images based SM in AP direction (Σ: -1.39 mm vs 5.57 mm, P=0.003; σ: 0.00 mm vs 3.2 mm, P=0.003). Conclusions: Compared with kilovolt X-ray images, CBCT underestimate the setup error in the AP direction, but decreases setup residual error significantly.An image-guided radiotherapy and setup error assessment using kilovolt X-ray images for EB-PBI plans was feasible. (authors)

The economic impact of revision otologic surgery.

Science.gov (United States)

Nadimi, Sahar; Leonetti, John P; Pontikis, George

2016-03-01

Revision otologic surgery places a significant economic burden on patients and the healthcare system. We conducted a retrospective chart analysis to estimate the economic impact of revision canal-wall-down (CWD) mastoidectomy. We reviewed the medical records of all 189 adults who had undergone CWD mastoidectomy performed by the senior author between June 2006 and August 2011 at Loyola University Medical Center in Maywood, Ill. Institutional charges and collections for all patients were extrapolated to estimate the overall healthcare cost of revision surgery in Illinois and at the national level. Of the 189 CWD mastoidectomies, 89 were primary and 100 were revision procedures. The total charge for the revision cases was $2,783,700, and the net reimbursement (collections) was $846,289 (30.4%). Using Illinois Hospital Association data, we estimated that reimbursement for 387 revision CWD mastoidectomies that had been performed in fiscal year 2011 was nearly $3.3 million. By extrapolating our data to the national level, we estimated that 9,214 patients underwent revision CWD mastoidectomy in the United States during 2011, which cost the national healthcare system roughly $76 million, not including lost wages and productivity. Known causes of failed CWD mastoidectomies that often result in revision surgery include an inadequate meatoplasty, a facial ridge that is too high, residual diseased air cells, and recurrent cholesteatoma. A better understanding of these factors can reduce the need for revision surgery, which could have a positive impact on the economic strain related to this procedure at the local, state, and national levels.

2009.3 Revision of the Evaluated Nuclear Data Library (ENDL2009.3)

Energy Technology Data Exchange (ETDEWEB)

Thompson, I. J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Beck, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Descalle, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mattoon, C. M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jurgenson, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-11-06

LLNL's Computational Nuclear Data and Theory Group have created a 2009.3 revised release of the Evaluated Nuclear Data Library (ENDL2009.3). This library is designed to support LLNL's current and future nuclear data needs and will be employed in nuclear reactor, nuclear security and stockpile stewardship simulations with ASC codes. The ENDL2009 database was the most complete nuclear database for Monte Carlo and deterministic transport of neutrons and charged particles. It was assembled with strong support from the ASC PEM and Attribution programs, leveraged with support from Campaign 4 and the DOE/Office of Science's US Nuclear Data Program. This document lists the revisions and fixes made in a new release called ENDL2009.3, by com- paring with the existing data in the previous release ENDL2009.2. These changes are made in conjunction with the revisions for ENDL2011.3, so that both the .3 releases are as free as possible of known defects.

2011.2 Revision of the Evaluated Nuclear Data Library (ENDL2011.2)

Energy Technology Data Exchange (ETDEWEB)

Beck, B. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Descalles, M. A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mattoon, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Jurgenson, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Thompson, I. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

2017-09-22

LLNL's Computational Nuclear Physics Group and Nuclear Theory and Modeling Group have col- laborated to create the 2011.2 revised release of the Evaluated Nuclear Data Library (ENDL2011.2). ENDL2011.2 is designed to support LLNL's current and future nuclear data needs and will be em- ployed in nuclear reactor, nuclear security and stockpile stewardship simulations with ASC codes. This database is currently the most complete nuclear database for Monte Carlo and deterministic transport of neutrons and charged particles. This library was assembled with strong support from the ASC PEM and Attribution programs, leveraged with support from Campaign 4 and the DOE/O ce of Science's US Nuclear Data Program. This document lists the revisions made in ENDL2011.2 compared with the data existing in the original ENDL2011.0 release and the ENDL2011.1-rc4 re- lease candidate of April 2015. These changes are made in parallel with some similar revisions for ENDL2009.2.

Kamptonema (Microcoleaceae, Cyanobacteria), a new genus derived from the polyphyletic Phormidium on the basis of combined molecular and cytomorphological markers

Czech Academy of Sciences Publication Activity Database

Strunecký, Otakar; Komárek, Jiří; Šmarda, J.

2014-01-01

Roč. 86, č. 2 (2014), 193-207 ISSN 0032-7786 R&D Projects: GA ČR GAP506/12/1818 Institutional support: RVO:67985939 Keywords : cyanobacteria * taxonomic revision * polyphasic approach Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.104, year: 2014

How to Revise, and Revise Really Well, for Premier Academic Journals

DEFF Research Database (Denmark)

LaPlaca, Peter J.; Lindgreen, Adam; Vanhamme, Joelle

2018-01-01

Most of the premier academic journals in all fields routinely have rejection rates of 80%, 95%, or higher. All journals prefer articles that make significant contributions to the field. Revising a manuscript and responding properly to the comments of reviewers and editors often is challenging....... This article discusses how to revise effectively a manuscript according to the (minor or major) comments of reviewers and editors for premier academic journals. We provide a series of tips for helping the authors in their endeavor, making the process less arduous and improving the possibility of a positive...

A taxonomic revision of the genus Podocarpus

NARCIS (Netherlands)

Laubenfels, de D.J.

1985-01-01

In connection with the forthcoming revision of the Coniferae for the Flora Malesiana, the author thought it necessary to revise the genus Podocarpus. Although this genus has a substantial representation in Malesia (30 species), the revision is too involved to be appropriate with the Flora Malesiana

Decommissioning plan - decommissioning project for KRR 1 and 2 (revised)

Energy Technology Data Exchange (ETDEWEB)

Jung, K. J.; Paik, S. T.; Chung, U. S.; Jung, K. H.; Park, S. K.; Lee, D. G.; Kim, H. R.; Kim, J. K.; Yang, S. H.; Lee, B. J

2000-10-01

This report is the revised Decommissioning Plan for the license of TRIGA research reactor decommissioning project according to Atomic Energy Act No. 31 and No. 36. The decommissioning plan includes the TRIGA reactor facilities, project management, decommissioning method, decontamination and dismantling activity, treatment, packaging, transportation and disposal of radioactive wastes. the report also explained the radiation protection plan and radiation safety management during the decommissioning period, and expressed the quality assurance system during the period and the site restoration after decommissioning. The first decommissioning plan was made by Hyundai Engineering Co, who is the design service company, was submitted to the Ministry of Science and Technology, and then was reviewed by the Korea Institute of Nuclear Safety. The first decommissioning plan was revised including answers for the questions arising from review process.

Decommissioning plan - decommissioning project for KRR 1 and 2 (revised)

International Nuclear Information System (INIS)

Jung, K. J.; Paik, S. T.; Chung, U. S.; Jung, K. H.; Park, S. K.; Lee, D. G.; Kim, H. R.; Kim, J. K.; Yang, S. H.; Lee, B. J.

2000-10-01

This report is the revised Decommissioning Plan for the license of TRIGA research reactor decommissioning project according to Atomic Energy Act No. 31 and No. 36. The decommissioning plan includes the TRIGA reactor facilities, project management, decommissioning method, decontamination and dismantling activity, treatment, packaging, transportation and disposal of radioactive wastes. the report also explained the radiation protection plan and radiation safety management during the decommissioning period, and expressed the quality assurance system during the period and the site restoration after decommissioning. The first decommissioning plan was made by Hyundai Engineering Co, who is the design service company, was submitted to the Ministry of Science and Technology, and then was reviewed by the Korea Institute of Nuclear Safety. The first decommissioning plan was revised including answers for the questions arising from review process

Nevada Test Site Radiological Control Manual. Revision 1

Energy Technology Data Exchange (ETDEWEB)

None, None

2010-02-09

This document supersedes DOE/NV/25946--801, “Nevada Test Site Radiological Control Manual,” Revision 0 issued in October 2009. Brief Description of Revision: A minor revision to correct oversights made during revision to incorporate the 10 CFR 835 Update; and for use as a reference document for Tenant Organization Radiological Protection Programs.

Structures of human cytosolic and mitochondrial nucleotidases: implications for structure-based design of selective inhibitors

Czech Academy of Sciences Publication Activity Database

Pachl, Petr; Fábry, Milan; Rosenberg, Ivan; Šimák, Ondřej; Řezáčová, Pavlína; Brynda, Jiří

2014-01-01

Roč. 70, February (2014), s. 461-470 ISSN 0907-4449 R&D Projects: GA ČR GA203/09/0820 Institutional support: RVO:68378050 ; RVO:61388963 Keywords : 5′(3′)-deoxyribonucleotidases * enzyme inhibition * hydrolases * structure-based drug design Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 7.232, year: 2013

Solar Power Tower Design Basis Document, Revision 0

Energy Technology Data Exchange (ETDEWEB)

ZAVOICO,ALEXIS B.

2001-07-01

This report contains the design basis for a generic molten-salt solar power tower. A solar power tower uses a field of tracking mirrors (heliostats) that redirect sunlight on to a centrally located receiver mounted on top a tower, which absorbs the concentrated sunlight. Molten nitrate salt, pumped from a tank at ground level, absorbs the sunlight, heating it up to 565 C. The heated salt flows back to ground level into another tank where it is stored, then pumped through a steam generator to produce steam and make electricity. This report establishes a set of criteria upon which the next generation of solar power towers will be designed. The report contains detailed criteria for each of the major systems: Collector System, Receiver System, Thermal Storage System, Steam Generator System, Master Control System, and Electric Heat Tracing System. The Electric Power Generation System and Balance of Plant discussions are limited to interface requirements. This design basis builds on the extensive experience gained from the Solar Two project and includes potential design innovations that will improve reliability and lower technical risk. This design basis document is a living document and contains several areas that require trade-studies and design analysis to fully complete the design basis. Project- and site-specific conditions and requirements will also resolve open To Be Determined issues.

Extending an evidence hierarchy to include topics other than treatment: revising the Australian 'levels of evidence'

Science.gov (United States)

2009-01-01

Background In 1999 a four-level hierarchy of evidence was promoted by the National Health and Medical Research Council in Australia. The primary purpose of this hierarchy was to assist with clinical practice guideline development, although it was co-opted for use in systematic literature reviews and health technology assessments. In this hierarchy interventional study designs were ranked according to the likelihood that bias had been eliminated and thus it was not ideal to assess studies that addressed other types of clinical questions. This paper reports on the revision and extension of this evidence hierarchy to enable broader use within existing evidence assessment systems. Methods A working party identified and assessed empirical evidence, and used a commissioned review of existing evidence assessment schema, to support decision-making regarding revision of the hierarchy. The aim was to retain the existing evidence levels I-IV but increase their relevance for assessing the quality of individual diagnostic accuracy, prognostic, aetiologic and screening studies. Comprehensive public consultation was undertaken and the revised hierarchy was piloted by individual health technology assessment agencies and clinical practice guideline developers. After two and a half years, the hierarchy was again revised and commenced a further 18 month pilot period. Results A suitable framework was identified upon which to model the revision. Consistency was maintained in the hierarchy of "levels of evidence" across all types of clinical questions; empirical evidence was used to support the relationship between study design and ranking in the hierarchy wherever possible; and systematic reviews of lower level studies were themselves ascribed a ranking. The impact of ethics on the hierarchy of study designs was acknowledged in the framework, along with a consideration of how harms should be assessed. Conclusion The revised evidence hierarchy is now widely used and provides a common

Extending an evidence hierarchy to include topics other than treatment: revising the Australian 'levels of evidence'

Directory of Open Access Journals (Sweden)

Merlin Tracy

2009-06-01

Full Text Available Abstract Background In 1999 a four-level hierarchy of evidence was promoted by the National Health and Medical Research Council in Australia. The primary purpose of this hierarchy was to assist with clinical practice guideline development, although it was co-opted for use in systematic literature reviews and health technology assessments. In this hierarchy interventional study designs were ranked according to the likelihood that bias had been eliminated and thus it was not ideal to assess studies that addressed other types of clinical questions. This paper reports on the revision and extension of this evidence hierarchy to enable broader use within existing evidence assessment systems. Methods A working party identified and assessed empirical evidence, and used a commissioned review of existing evidence assessment schema, to support decision-making regarding revision of the hierarchy. The aim was to retain the existing evidence levels I-IV but increase their relevance for assessing the quality of individual diagnostic accuracy, prognostic, aetiologic and screening studies. Comprehensive public consultation was undertaken and the revised hierarchy was piloted by individual health technology assessment agencies and clinical practice guideline developers. After two and a half years, the hierarchy was again revised and commenced a further 18 month pilot period. Results A suitable framework was identified upon which to model the revision. Consistency was maintained in the hierarchy of "levels of evidence" across all types of clinical questions; empirical evidence was used to support the relationship between study design and ranking in the hierarchy wherever possible; and systematic reviews of lower level studies were themselves ascribed a ranking. The impact of ethics on the hierarchy of study designs was acknowledged in the framework, along with a consideration of how harms should be assessed. Conclusion The revised evidence hierarchy is now widely

Mechanical properties of TIG and EB weld joints of F82H

Energy Technology Data Exchange (ETDEWEB)

Hirose, Takanori, E-mail: hirose.takanori@jaea.go.jp; Sakasegawa, Hideo; Nakajima, Motoki; Tanigawa, Hiroyasu

2015-10-15

Highlights: • Narrow groove TIG minimized volume of F82H weld. • Mechanical properties of TIG and EB welds of F82H have been characterized. • Post weld heat treatment successfully moderate the toughness of weld metal without softening the base metal. - Abstract: This work investigates mechanical properties of weld joints of a reduced activation ferritic/martensitic steel, F82H and effects of post weld heat treatment on the welds. Vickers hardness, tensile and Charpy impact tests were conducted on F82H weld joints prepared using tungsten-inert-gas and electron beam after various heat treatments. Although narrow groove tungsten-inert-gas welding reduced volume of weld bead, significant embrittlement was observed in a heat affected zone transformed due to heat input. Post weld heat treatment above 993 K successfully moderated the brittle transformed region. The hardness of the brittle region strongly depends on the heat treatment temperature. Meanwhile, strength of base metal was slightly reduced by the treatment at temperature ranging from 993 to 1053 K. Moreover, softening due to double welding was observed only in the weld metal, but negligible in base metal.

Decision making models and human factors: TOPSIS and Ergonomic Behaviors (TOPSIS-EB

Directory of Open Access Journals (Sweden)

Mohammad

2017-02-01

Full Text Available An effective safety management requires attention to human factors as well as system compo-nents which make risky or safe situations at technical components. This study evaluates and ana-lyze ergonomic behaviors in order to select the best work shift group in an Iranian process in-dustry, in 2010.The methodology was based on the Ergonomic Behavior Sampling (EBS, and TOPSIS method. After specifying the unergonomic behaviors and with reference to the results of a pilot study, a sample of 1755 was determined, with a sampling accuracy of 5% and confi-dence level of 95%. However, in order to gain more confidence, 2631 observations were collect-ed. The results indicate that 43.6% of workers’ behaviors were unergonomic. The most frequent unergonomic behavior was amusing of legs while load lifting with 83.01% of total unergonomic behaviors observations. Using TOPSIS method, the most effective shift group and the least at-tractive alternatives for intervention were selected in this company. Findings declare high number of unergonomic behaviors. Catastrophic consequences of accidents in petrochemical industry ne-cessitate attention to workers’ ergonomic behaviors in the workplace and promotion of them.

Projekt v prostředí sportovních a tělovýchovných služeb - Rekondiční centrum Brno

OpenAIRE

Musilová, Erika

2015-01-01

Bakalářská práce řeší projekt v prostředí sportovních a tělovýchovných služeb.práce je zpracovat projekt rekondičního centra. Bakalářská práce vychází z analýzy zařízení a z porovnání center stejného typu v jiných městech České republiky. Práce uvádí vlastní návrhy na zlepšení služeb rekondičního centra v Brně a celé sítě rekondičních center formou franchisingu. This bachelor's thesis deals with a project in the sports and physical education environment. The target is to develop a project ...

Synthesis and characterization of PEFC membranes based on fluorinated-polymer-alloy using pre-soft-EB grafting method

International Nuclear Information System (INIS)

Muto, Fumihiro; Oshima, Akihiro; Kakigi, Tomoyuki; Mitani, Naohiro; Matsuura, Akio; Fujii, Kazuki; Sato, Yukiko; Li Jingye; Washio, Masakazu

2007-01-01

Polymer electrolyte fuel cell (PEFC) membranes based on thin film of crosslinked perfluorinated polymer-alloys (RX-FA) have been fabricated by soft electron beam (soft-EB) grafting with styrene monomers using soft-EB irradiation under nitrogen atmosphere at room temperature (RT). The characteristic properties of styrene-grafted materials (GRX-FA) and sulfonated materials (SRX-FA) have been measured by differential scanning calorimetry (DSC) and FT-IR spectroscopy, ionic conductivity and so on. The glass transition temperatures (dry state) of all obtained SRX-FA were about 105 ± 1 deg. C, which are higher than Nafion. The ion exchange capacities of SRX-FA have been achieved about 3.3 meq/g (dry). The ionic conductivity of obtained SRX-FA has showed about 0.17 S/cm at 60 deg. C with relative humidity (RH) of ∼95%. The ionic conductivities of the obtained SRX-FA were higher than that of conventional perfluoro-sulfonic acid membranes (PFSA). Fabricated membrane electrode assemblies (MEAs) based on the obtained SRX-FA have shown encouraging performance in the PEFC, compared with the conventional PFSA. The power density of obtained MEAs based on the SRX-FA was about 330-340 mW/cm 2 under 500 mA/cm 2 at 60 deg. C operation. Moreover, the maximum power densities of obtained MEAs based on the SRX-FA shows about 630 mW/cm 2 at 60 deg. C. On the other hand, the power density at 500 mA/cm 2 and maximum power density of MEA based on Nafion 112 were about 320 and 590 mW/cm 2 at 60 deg. C. Thus, the power density of the obtained SRX-FA was higher than that of conventional PFSA

The Arabidopsis mitogen-activated protein kinase 6 is associated with γ-tubulin on microtubules, phosphorylates EB1c and maintains spindle orientation under nitrosative stress

Czech Academy of Sciences Publication Activity Database

Kohoutová, Lucie; Kourová, Hana; Nagy, S. K.; Volc, Jindřich; Halada, Petr; Mészáros, T.; Meskiene, I.; Bögre, L.; Binarová, Pavla

2015-01-01

Roč. 207, č. 4 (2015), s. 1061-1074 ISSN 0028-646X R&D Projects: GA MŠk 7AMB13AT013; GA ČR GAP501/12/2333 Institutional support: RVO:61388971 Keywords : Arabidopsis * cell division * EB1c Subject RIV: EE - Microbiology, Virology Impact factor: 7.210, year: 2015

[An overview on the collation and revision of medical books by the Bureau for Revising Medical Books in the Northern Song Dynasty].

Science.gov (United States)

Meng, Yongliang; Liang, Yongxuan

2014-07-01

The Bureau for Revising Medical Books was a temporary agency established by the government of the Northern Song Dynasty in 1057, the 2nd year of Jiayou of Emperor Renzong, exclusively for the edition, revision and publishing of ancient medical books. 11 medical books were revised and edited by 13 Bureau members in a period of 12 years until 1069, the 2nd year of Xining of Emperor ShenZong, which eventually became the final versions until today. 8 medical books were initially planned for the revision, but 11 were actually completed in the end. The time for completing a revision varied from over 10 years at most to less than 1 year at least. Instead of working in the office, the officers of the Bureau for Revising Medical Books did their works at home. The members of the said Bureau came from the Tiju officer of the Bureau for Revising Medical Books and the officials of revising medical books, consisting of both Confucian ministers and medical officers. Confucian ministers played an important role in revising medical books. The Bureau had a strict workflow in electing revising officials, making the project, and the determination of the principles and arrangements of the tasks of editing and proofreading.

Emotion Processes in Knowledge Revision

Science.gov (United States)

Trevors, Gregory J.; Kendeou, Panayiota; Butterfuss, Reese

2017-01-01

In recent years, a number of insights have been gained into the cognitive processes that explain how individuals overcome misconceptions and revise their previously acquired incorrect knowledge. The current study complements this line of research by investigating the moment-by-moment emotion processes that occur during knowledge revision using a…

75 FR 57597 - Revised Proposal for Revisions to the Schedules of Civil Penalties for a Violation of a Federal...

Science.gov (United States)

2010-09-21

... Revisions to the Schedules of Civil Penalties for a Violation of a Federal Railroad Safety Law or Federal... railroad safety laws and regulations are necessary because many of FRA's civil penalties have not been..., et al. Revised Proposal for Revisions to the Schedules of Civil Penalties for a Violation of a...

Improvement in ductility of high strength polycrystalline Ni-rich Ni{sub 3}Al alloy produced by EB-PVD

Energy Technology Data Exchange (ETDEWEB)

Sun, J.Y.; Pei, Y.L.; Li, S.S.; Zhang, H.; Gong, S.K., E-mail: gongsk@buaa.edu.cn

2014-11-25

Highlights: • High strength and high ductility of polycrystalline Ni-rich Ni{sub 3}Al alloy sheets were produced. • The elongation could be enhanced from ∼0.5% to ∼14.6% by microstructural control. • The fracture strength (∼820 MPa) was enhanced by the precipitation strengthening. • This work provides a general processing for repairing the worn single crystal blades. - Abstract: A 300 μm Ni-rich Ni{sub 3}Al sheet was produced by electron beam physical vapor deposition (EB-PVD) and followed by different heat treatments to obtain fine γ′/γ two-phase structures with large elongation. Tensile testing was performed at room-temperature, and the corresponding mechanisms were investigated in detail. Results indicated that the as-deposited Ni{sub 3}Al alloy exhibited non-equilibrium directional columnar crystal, and transited to equiaxed crystal with uniformly distributed tough γ phase after heat treatment. Meanwhile, the fracture mechanism transited from brittleness to a mixture of ductility and brittleness modes. With an appropriate heat treatment, high strength (ultimate tensile strength obtained 828 MPa) and high ductility (elongation obtained 14.6%) Ni{sub 3}Al alloy has been achieved, which was due to the mesh network microstructure. A series of transmission electron microscope (TEM) characterizations confirmed that the increasing flow stress of Ni{sub 3}Al alloy was attributed to the cubical secondary γ′ phase precipitates (25–50 nm) within the γ phase. This work provides a potential strategy for repairing the worn tip of single crystal engine blades using Ni-rich Ni{sub 3}Al alloy by EB-PVD.

49 CFR 79.9 - Design.

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Design. 79.9 Section 79.9 Transportation Office of the Secretary of Transportation MEDALS OF HONOR § 79.9 Design. The Department is authorized to adopt and revise the existing designs for the award, rosette, and ribbon provided for by statute. ...

Revised reactor accident source terms in the U.S. and implementation for light water reactors

International Nuclear Information System (INIS)

Soffer, L.; Lee, J.Y.

1992-01-01

Current NRC reactor accident source terms used for licensing are contained in Regulatory Guides 1.3 and 1.4 and specify that 100 % of the core inventory of noble gases and 25 % of the iodine fission products are assumed to be instantaneously available for release from the containment. The chemical form of the iodine fission products is also assumed to be predominantly elemental (I 2 ) iodine. These assumptions have strongly affected present nuclear plant designs. Severe accident research results have confirmed that although the current source term is very substantial and has resulted in a very high level of plant capability, the present source term is no longer compatible with a realistic understanding of severe accidents. The NRC has issued a proposed revision of the reactor accident source terms as part of several regulatory activities to incorporate severe accident insights for future plants. A revision to 10 CFR 100 is also being proposed to specify site criteria directly and to eliminate source terms and doses for site evaluation. Reactor source terms will continue to be important in evaluating plant designs. Although intended primarily for future plants, existing and evolutionary power plants may voluntarily apply revised accident source term insights as well in licensing. The proposed revised accident source terms are presented in terms of fission product composition, magnitude, timing and iodine chemical form. Some implications for light water reactors are discussed. (author)

Design Improvement of Double Pressure Vessel in the In-pile Test Section

Energy Technology Data Exchange (ETDEWEB)

Hong, Jintae; Heo, Sung-Ho; Joung, Chang-Young; Kim, Ka-Hye [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2014-10-15

To carry out an irradiation test of nuclear fuels, a nuclear fuel test rig should be fabricated and installed in the in-pile test section (IPS), which is installed in the reactor hall. While carrying out an irradiation test, sealing out coolant which passes through the test rig is one of the most important issues. In particular, although the double pressure vessel is assembled with the IPS head by two o-rings and six bolts, 15.5 MPa of highly pressurized coolant leaks through the gap between the vessel and IPS head. Because the temperature of the coolant in the test loop is 300 .deg. C , and the pool of HANARO is 40 .deg. C, the double pressure vessel is necessary to insulate them. Therefore, a new design to prevent the leakage of coolant needs to be developed. In this study, EB welding technique is considered to assemble the double pressure vessel and the IPS head, and their mechanical design is modified to enable the welding process. In this study, an improved design for sealing out the coolant at the pressure boundary between the double pressure vessel and the IPS head has been developed. An EB weld is applied to seal out the pressure boundary, and its sealing performance is verified by NDE, a cross section test, and a hydraulic pressure test. From the verification test results, the improved design can be used in fabricating the IPS for a nuclear fuel irradiation test.

Towards a revision of the genus Periclimenes: resurrection of Ancylocaris Schenkel, 1902, and designation of three new genera (Crustacea, Decapoda, Palaemonidae

Directory of Open Access Journals (Sweden)

Zdeněk Ďuriš

2017-01-01

Full Text Available Based on recently published molecular phylogenies of Indo-West Pacific palaemonid shrimps and further morphological evidence, the systematic position of several species of the polyphyletic genus Periclimenes is revised. The generic name Ancylocaris Schenkel, 1902 is re-established for the anemone-associated P. brevicarpalis. Actinimenes gen. n., is proposed for the anemone-associated P. inornatus, P. ornatellus and P. ornatus, all of which have a subspatulate first pereiopod. Cristimenes gen. n., is designated for the echinoderm-associated species, P. commensalis, P. cristimanus, and P. zanzibaricus, all with a unique carpo-propodal articulation of the second pereiopods. Rapimenes gen. n. is established for the hydroid and antipatharian-associated P. brucei, P. granulimanus, and P. laevimanus, for which the long, slender and unequal second pereiopods and prehensile ambulatory propodi are the main synapomorphic characters.

Revised licensee event report system

International Nuclear Information System (INIS)

Mays, G.T.; Poore, W.P.

1985-01-01

Licensee Event Reports (LERs) provide the basis for evaluating and assessing operating experience information from nuclear power plants. The reporting requirements for submitting LERs to the Nuclear Regulatory Commission have been revised. Effective Jan. 1, 1984, all events were to be submitted in accordance with 10 CFR 50.73 of the Code of Federal Regulations. Report NUREG-1022, Licensee Event Report System-Description of System and Guidelines for Reporting, describes the guidelines on reportability of events. This article summarizes the reporting requirements as presented in NUREG-1022, high-lights differences in data reported between the revised and previous LER systems, and presents results from a preliminary assessment of LERs submitted under the revised LER reporting system

Design parameters and source terms: Volume 1, Design parameters: Revision 0

International Nuclear Information System (INIS)

1987-09-01

The Design Parameters and Source Terms Document was prepared in accordance with DOE request and to provide data for the environmental impact study to be performed in the future for the Deaf Smith County, Texas site for a nuclear waste repository in salt. This document updates a previous unpublished report to the level of the Site Characterization Plan - Conceptual Design Report, SCP-CDR. The previous unpublished SCC Study identified the data needs for the Environmental Assessment effort for seven possible salt repository sites

Revised upper limb module for spinal muscular atrophy: Development of a new module.

Science.gov (United States)

Mazzone, Elena S; Mayhew, Anna; Montes, Jacqueline; Ramsey, Danielle; Fanelli, Lavinia; Young, Sally Dunaway; Salazar, Rachel; De Sanctis, Roberto; Pasternak, Amy; Glanzman, Allan; Coratti, Giorgia; Civitello, Matthew; Forcina, Nicola; Gee, Richard; Duong, Tina; Pane, Marika; Scoto, Mariacristina; Pera, Maria Carmela; Messina, Sonia; Tennekoon, Gihan; Day, John W; Darras, Basil T; De Vivo, Darryl C; Finkel, Richard; Muntoni, Francesco; Mercuri, Eugenio

2017-06-01

There is a growing need for a robust clinical measure to assess upper limb motor function in spinal muscular atrophy (SMA), as the available scales lack sensitivity at the extremes of the clinical spectrum. We report the development of the Revised Upper Limb Module (RULM), an assessment specifically designed for upper limb function in SMA patients. An international panel with specific neuromuscular expertise performed a thorough review of scales currently available to assess upper limb function in SMA. This review facilitated a revision of the existing upper limb function scales to make a more robust clinical scale. Multiple revisions of the scale included statistical analysis and captured clinically relevant changes to fulfill requirements by regulators and advocacy groups. The resulting RULM scale shows good reliability and validity, making it a suitable tool to assess upper extremity function in the SMA population for multi-center clinical research. Muscle Nerve 55: 869-874, 2017. © 2016 Wiley Periodicals, Inc.

Clinical and Economic Burden of Revision Knee Arthroplasty

Directory of Open Access Journals (Sweden)

Mohit Bhandari

2012-01-01

Full Text Available Surgery is indicated for symptomatic knee osteoarthritis (OA when conservative measures are unsuccessful. High tibial osteotomy (HTO, unicompartmental knee arthroplasty (UKA, and total knee arthroplasty (TKA are surgical options intended to relieve knee OA pain and dysfunction. The choice of surgical intervention is dependent on several factors such as disease location, patient age, comorbidities, and activity levels. Regardless of surgical treatment, complications such as infection, loosening or lysis, periprosthetic fracture, and postoperative pain are known risks and are indications for revision surgery. The clinical and economic implications for revision surgery are underappreciated. Over 55,000 revision surgeries were performed in 2010 in the US, with 48% of these revisions in patients under 65 years. Total costs associated with each revision TKA surgery have been estimated to be in excess of $49,000. The current annual economic burden of revision knee OA surgery is $2.7 billion for hospital charges alone. By 2030, assuming a 5-fold increase in the number of revision procedures, this economic burden will exceed $13 billion annually. It is appealing to envision a therapy that could delay or obviate the need for arthroplasty. From an actuarial standpoint, this would have the theoretical downstream effect of substantially reducing the number of revision procedures. Although no known therapies currently meet these criteria, such a breakthrough would have a tremendous impact in lessening the clinical and economic burden of knee OA revision surgery.

Mechanical properties of EB-PVD ZrO2 thermal barrier coatings

International Nuclear Information System (INIS)

Held, Carolin

2014-01-01

In this work, the elastic properties of thermal barrier coatings which were produced by electron-beam enhanced physical vapour deposition were investigated, as well as the dependency of the properties on the sample microstructure, the thermal treatment and the test method. For this purpose, not only commercial coatings were characterized, but also special sample material was used which consists of a 1 mm thick layer of EB-PVD TBC. This material was isothermally heat treated for different times at 950 C, 1100 C and 1200 C and then tested in a specially developed miniaturized bend test and by dynamic mechanical analysis. The sample material was tested by nanoindentation in order to measure the Young's modulus on a local scale, and the porosity of the samples was determined by microstructure analysis and porosimetry. The decrease of porosity could be connected with sintering and subsequent stiffening of the material. The test results are dependent on the tested volume. A small test volume leads to larger measured Young's moduli, while a large test volume yields lower values. The test volume also has an influence on the increase of stiffness during thermal exposure. With a small tested volume, a quicker increase of the Young's modulus was registered, which could be associated to the sintering of local structures.

Humeral windows in revision total elbow arthroplasty.

Science.gov (United States)

Peach, Chris A; Salama, Amir; Stanley, David

2016-04-01

The use of cortical windows for revision elbow arthroplasty has not previously been widely reported. Their use aids safe revision of a well fixed humeral prosthesis and can be used in the setting of dislocation, periprosthetic fracture or aseptic loosening of the ulnar component. We describe our technique and results of cortical windows in the distal humerus for revision elbow arthroplasty surgery.

Diet History Questionnaire: Database Revision History

Science.gov (United States)

The following details all additions and revisions made to the DHQ nutrient and food database. This revision history is provided as a reference for investigators who may have performed analyses with a previous release of the database.

Revised SRAC code system

International Nuclear Information System (INIS)

Tsuchihashi, Keichiro; Ishiguro, Yukio; Kaneko, Kunio; Ido, Masaru.

1986-09-01

Since the publication of JAERI-1285 in 1983 for the preliminary version of the SRAC code system, a number of additions and modifications to the functions have been made to establish an overall neutronics code system. Major points are (1) addition of JENDL-2 version of data library, (2) a direct treatment of doubly heterogeneous effect on resonance absorption, (3) a generalized Dancoff factor, (4) a cell calculation based on the fixed boundary source problem, (5) the corresponding edit required for experimental analysis and reactor design, (6) a perturbation theory calculation for reactivity change, (7) an auxiliary code for core burnup and fuel management, etc. This report is a revision of the users manual which consists of the general description, input data requirements and their explanation, detailed information on usage, mathematics, contents of libraries and sample I/O. (author)

Revision surgery for failed thermal capsulorrhaphy.

Science.gov (United States)

Park, Hyung Bin; Yokota, Atsushi; Gill, Harpreet S; El Rassi, George; McFarland, Edward G

2005-09-01

With the failure of thermal capsulorrhaphy for shoulder instability, there have been concerns with capsular thinning and capsular necrosis affecting revision surgery. To report the findings at revision surgery for failed thermal capsulorrhaphy and to evaluate the technical effects on subsequent revision capsular plication. Case series; Level of evidence, 4. Fourteen patients underwent arthroscopic evaluation and open reconstruction for a failed thermal capsulorrhaphy. The cause of the failure, the quality of the capsule, and the ability to suture the capsule were recorded. The patients were evaluated at follow-up for failure, which was defined as recurrent subluxations or dislocations. The origin of the instability was traumatic (n = 6) or atraumatic (n = 8). At revision surgery in the traumatic group, 4 patients sustained failure of the Bankart repair with capsular laxity, and the others experienced capsular laxity alone. In the atraumatic group, all patients experienced capsular laxity as the cause of failure. Of the 14 patients, the capsule quality was judged to be thin in 5 patients and ablated in 1 patient. A glenoid-based capsular shift could be accomplished in all 14 patients. At follow-up (mean, 35.4 months; range, 22 to 48 months), 1 patient underwent revision surgery and 1 patient had a subluxation, resulting in a failure rate of 14%. Recurrent capsular laxity after failed thermal capsular shrinkage is common and frequently associated with capsular thinning. In most instances, the capsule quality does not appear to technically affect the revision procedure.

The New Indices of Religious Orientation Revised (NIROR: A Study among Canadian Adolescents Attending a Baptist Youth Mission and Service Event

Directory of Open Access Journals (Sweden)

Leslie J. Francis

2016-05-01

Full Text Available This study explores the properties of the New Indices of Religious Orientation Revised (NIROR among a sample of 521 Canadian adolescents attending a Baptist youth mission and service event, ranging in age from 12 to 19 years. This revision simplified the language of the original instrument to increase its accessibility among young people. The data support the internal consistency reliability and construct validity of the three revised nine-item scales designed to operationalise extrinsic religious orientation, intrinsic religious orientation, and quest religious orientation.

Salt Repository Project input to seismic design: Revision 0

International Nuclear Information System (INIS)

1987-12-01

The Salt Repository Program (SRP) Input to Seismic Design (ISD) documents the assumptions, rationale, approaches, judgments, and analyses that support the development of seismic-specific data and information to be used for shaft design in accordance with the SRP Shaft Design Guide (SDG). The contents of this document are divided into four subject areas: (1) seismic assessment, (2) stratigraphy and material properties for seismic design, (3) development of seismic design parameters, and (4) host media stability. These four subject areas have been developed considering expected conditions at a proposed site in Deaf Smith County, Texas. The ISD should be used only in conjunction with seismic design of the exploratory and repository shafts. Seismic design considerations relating to surface facilities are not addressed in this document. 54 refs., 55 figs., 18 tabs

Reference design description for a geologic repository: Revision 01

International Nuclear Information System (INIS)

1997-09-01

This document describes the current design expectations for a potential geologic repository that could be located at Yucca Mountain in Nevada. This Reference Design Description (RDD) looks at the surface and subsurface repository and disposal container design. Additionally, it reviews the expected long-term performance of the potential repository. In accordance with current legislation, the reference design for the potential repository does not include an interim storage option. The reference design presented allows the disposal of highly radioactive material received from government-owned spent fuel custodian sites; produces high-level waste sites, and commercial spent fuel sites. All design elements meet current federal, state, and local regulations governing the disposal of high-level radioactive waste and protection of the public and the environment. Due to the complex nature of developing a repository, the design will be created in three phases to support Viability Assessment, License Application, and construction. This document presents the current reference design. It will be updated periodically as the design progresses. Some of the details presented here may change significantly as more cost-effective solutions, technical advancements, or changes to requirements are identified

77 FR 38765 - Notice of Intent To Revise a Currently Approved Information Collection

Science.gov (United States)

2012-06-29

... Congress and other government agencies, the forms are not designed to be statistical surveys. NIFA requires... application being submitted. This form is being revised to change the application type names and some business... June 2012. Catherine E. Woteki, Under Secretary, Research, Education, and Economics. [FR Doc. 2012...

Dismantling of the EB experiment: Experimental research on the retrieved GBM and bentonite blocks

Energy Technology Data Exchange (ETDEWEB)

Liu, Jiang-Feng, E-mail: jeafliu@hotmail.com [State Key Laboratory for Geomchanics & Deep Underground Engineering, and School of Mechanics and Civil Engineering, China University of Mining & Technology, Xuzhou, Jiangsu 221116 (China); Laboratoire de Méchanique de Lille (LML), and École Centrale de Lille, BP 48, F-59651 Villeneuve d’Ascq Cedex (France); Skoczylas, Frédéric [Laboratoire de Méchanique de Lille (LML), and École Centrale de Lille, BP 48, F-59651 Villeneuve d’Ascq Cedex (France); Talandier, Jean [ANDRA, 1-7 rue Jean Monnet, 92298 Châtenay-Malabry Cedex (France); Pu, Hai [State Key Laboratory for Geomchanics & Deep Underground Engineering, and School of Mechanics and Civil Engineering, China University of Mining & Technology, Xuzhou, Jiangsu 221116 (China)

2016-04-15

Graphical abstract: - Highlights: • We present a demonstration of a new concept of HLW (high-level waste) repositories. • The hydro-mechanical characteristics of GBM and blocks were determined. • The water retention curves (WRCs) of GBM and blocks were presented. • The effective gas permeability of the GBM and blocks were measured. • The homogeneity of the GBM and blocks were investigated. - Abstract: The Engineered Barrier Emplacement Experiment in Opalinus Clay (EB experiment) was a full-scale test for the demonstration of a new concept of high-level waste (HLW) repositories in horizontal drifts in the Opalinus Clay formation. After 10.5 years of hydration, the EB experiment was dismantled in autumn 2012. Samples obtained from the granular bentonite material (GBM), and bentonite blocks were sent to a laboratory for further analysis. The bentonite samples analyzed at the Laboratory of Mechanic of Lille (LML) were obtained from the CMT1, CMT2, CMT3 and RW sections. Their physical states were determined, as were their effective gas permeability and swelling capacity at different relative humidity (RH) levels. The results indicate that the water contents of the GBM determined in the laboratory ranged between 25.63% and 44.88% and that the dry densities ranged between 1.13 and 1.44 g/cm{sup 3}. The blocks had water contents similar to (or slightly higher than) those of the GBM, and their dry densities had decreased from an initial value of 1.69 g/cm{sup 3} to values close to 1.30 g/cm{sup 3}, which were similar to the average values found in the GBM. The effective gas permeabilities of the GBM samples were within the range of 1.50 × 10{sup −22} m{sup 2} and 1.03 × 10{sup −17} m{sup 2}, whereas, the corresponding values of the samples obtained from the blocks were between 2.20 × 10{sup −21} m{sup 2} and 5.12 × 10{sup −21} m{sup 2}. The permeability values are primarily related to the dry densities and water contents of the samples. Contact with

New Toroid shielding design

CERN Multimedia

Hedberg V

On the 15th of June 2001 the EB approved a new conceptual design for the toroid shield. In the old design, shown in the left part of the figure above, the moderator part of the shielding (JTV) was situated both in the warm and cold areas of the forward toroid. It consisted both of rings of polyethylene and hundreds of blocks of polyethylene (or an epoxy resin) inside the toroid vacuum vessel. In the new design, shown to the right in the figure above, only the rings remain inside the toroid. To compensate for the loss of moderator in the toroid, the copper plug (JTT) has been reduced in radius so that a layer of borated polyethylene can be placed around it (see figure below). The new design gives significant cost-savings and is easier to produce in the tight time schedule of the forward toroid. Since the amount of copper is reduced the weight that has to be carried by the toroid is also reduced. Outgassing into the toroid vacuum was a potential problem in the old design and this is now avoided. The main ...

Introductory Business Textbook Revision Cycles: Are They Getting Shorter?

Science.gov (United States)

Zinser, Brian; Brunswick, Gary

2010-01-01

The rate of textbook revision cycles is examined in light of the recent trend towards more rapid revisions (and adoptions of textbooks). The authors conduct background research to better understand the context for textbook revision cycles and the environmental forces that have been influencing what appears to be more rapid textbook revisions. A…

Revised Rules for Concrete Bridges

DEFF Research Database (Denmark)

Thoft-Christensen, Palle; Jensen, F. M.; Middleton, C.

This paper is based on research performed for the Highway Agency, London, UK under the project DPU/9/44 "Revision of Bridge Assessment Rules Based on Whole Life Performance: Concrete Bridges" It contains details of a methodology which can be used to generate Whole Life (WL) reliability profiles....... These WL reliability profiles may be used to establish revised rules for Concrete Bridges....

Inferential revision in narrative texts: An ERP study.

Science.gov (United States)

Pérez, Ana; Cain, Kate; Castellanos, María C; Bajo, Teresa

2015-11-01

We evaluated the process of inferential revision during text comprehension in adults. Participants with high or low working memory read short texts, in which the introduction supported two plausible concepts (e.g., 'guitar/violin'), although one was more probable ('guitar'). There were three possible continuations: a neutral sentence, which did not refer back to either concept; a no-revise sentence, which referred to a general property consistent with either concept (e.g., '…beautiful curved body'); and a revise sentence, which referred to a property that was consistent with only the less likely concept (e.g., '…matching bow'). Readers took longer to read the sentence in the revise condition, indicating that they were able to evaluate their comprehension and detect a mismatch. In a final sentence, a target noun referred to the alternative concept supported in the revise condition (e.g., 'violin'). ERPs indicated that both working memory groups were able to evaluate their comprehension of the text (P3a), but only high working memory readers were able to revise their initial incorrect interpretation (P3b) and integrate the new information (N400) when reading the revise sentence. Low working memory readers had difficulties inhibiting the no-longer-relevant interpretation and thus failed to revise their situation model, and they experienced problems integrating semantically related information into an accurate memory representation.

Microstructure evolution during annealing of TiAl/NiCoCrAl multilayer composite prepared by EB-PVD

Energy Technology Data Exchange (ETDEWEB)

Zhang, Rubing, E-mail: zrb86411680@126.com [Department of Mechanics, School of Civil Engineering, Beijing Jiaotong University, Beijing 100044 (China); Zhang, Deming [Beijing General Research Institute of Mining and Metallurgy, Beijing 100044 (China); Chen, Guiqing [Center for Composite Materials, Harbin Institute of Technology, Harbin 150001 (China); Wang, Yuesheng [Department of Mechanics, School of Civil Engineering, Beijing Jiaotong University, Beijing 100044 (China)

2014-07-01

TiAl/NiCoCrAl laminate composite sheet with a thickness of 0.4–0.6 mm as well as a dimension of 150 mm × 100 mm was fabricated successfully by using electron beam physical vapor deposition (EB-PVD) method. The annealing treatment was processed at 1123 and 1323 K for 3 h in a high vacuum atmosphere, respectively. The phase composition and microstructure of TiAl/NiCoCrAl microlaminated sheet have been analyzed by X-ray diffraction (XRD), scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Based on the sheet characterization and results of the microstructure evolution during annealing treatment process, the diffusion mechanism of interfacial reaction in TiAl/NiCoCrAl microlaminate was investigated and discussed.

Programme for the Environmental Control at the Swedish Nuclear Facilities, Revision; Omgivningskontrollprogram foer de kaerntekniska anlaeggningarna, revision

Energy Technology Data Exchange (ETDEWEB)

Linden, Ann-Marie

2004-12-01

This report contains a revised version of the Environmental Monitoring Programme for the Swedish Nuclear Facilities. The revision is based on earlier experiences and evaluations. Some samples have been excluded. Some have been added, for example spruce cone and the food products apple and currant. The sediment samples of 2 cm length have been completed with samples of 10 cm length every fourth year to follow the migration of radio nuclides down the sediment layers over time. The revised Environmental Monitoring Programme is valid from the 1st of January 2005.

A revised approach to the ULDB design

Science.gov (United States)

Smith, M.; Cathey, H.

The National Aeronautics and Space Administration Balloon Program has experienced problems in the scaling up of the proposed Ultra Long Duration Balloon. Full deployment of the balloon envelope has been the issue for the larger balloons. There are a number of factors that contribute to this phenomenon. Analytical treatments of the deployment issue are currently underway. It has also been acknowledged that the current fabrication approach using foreshortening is costly, labor intensive, and requires significant handling during production thereby increasing the chances of inducing damage to the envelope. Raven Industries has proposed a new design and fabrication approach that should increase the probability of balloon deployment, does not require foreshortening, will reduce the handling, production labor, and reduce the final balloon cost. This paper will present a description of the logic and approach used to develop this innovation. This development consists of a serial set of steps with decision points that build upon the results of the previous steps. The first steps include limited material development and testing. This will be followed by load testing of bi-axial reinforced cylinders to determine the effect of eliminating the foreshortening. This series of tests have the goal of measuring the strain in the material as it is bi-axially loaded in a condition that closely replicated the application in the full-scale balloon. Constant lobe radius pumpkin shaped test structures will be designed and analyzed. This matrix of model tests, in conjunction with the deployment analyses, will help develop a curve that should clearly present the deployment relationship for this kind of design. This will allow the ``design space'' for this type of balloon to be initially determined. The materials used, analyses, and ground testing results of both cylinders and small pumpkin structures will be presented. Following ground testing, a series of test flights, staged in increments

“Revising Nabokov Revising”

Directory of Open Access Journals (Sweden)

Marie Bouchet

2010-10-01

Full Text Available Nabokov revised his works as he translated them and, on another plane, canon revisionism has been having its backlash and provoked other refracting waves. The purpose of the conference was to advance Nabokov studies through the discussion of how our view of Nabokov’s standing and his works today should be revised, especially after the publication of The Original of Laura. However the conference was not confined to just this theme, since “revising” is a word rich with implications. To borrow s...

Revision of failed shoulder hemiarthroplasty to reverse total arthroplasty: analysis of 157 revision implants.

Science.gov (United States)

Merolla, Giovanni; Wagner, Eric; Sperling, John W; Paladini, Paolo; Fabbri, Elisabetta; Porcellini, Giuseppe

2018-01-01

There remains a paucity of studies examining the conversion of failed hemiarthroplasty (HA) to reverse total shoulder arthroplasty (RTSA). Therefore, the purpose of this study was to examine a large series of revision HA to RTSA. A population of 157 patients who underwent conversion of a failed HA to a revision RTSA from 2006 through 2014 were included. The mean follow-up was 49 months (range, 24-121 months). The indications for revision surgery included instability with rotator cuff insufficiency (n = 127) and glenoid wear (n = 30); instability and glenoid wear were associated in 38 cases. Eight patients with infection underwent 2-stage reimplantation. Patients experienced significant improvements in their preoperative to postoperative pain and shoulder range of motion (P surgeries, secondary to glenoid component loosening (n = 3), instability (n = 3), humeral component disassembly (n = 2), humeral stem loosening (n = 1), and infection (n = 2). Implant survivorship was 95.5% at 2 years and 93.3% at 5 years. There were 4 reoperations including axillary nerve neurolysis (n = 2), heterotopic ossification removal (n = 1), and hardware removal for rupture of the metal cerclage for an acromial fracture (n = 1). At final follow-up, there were 5 "at-risk" glenoid components. Patients experience satisfactory pain relief and recovery of reasonable shoulder function after revision RTSA from a failed HA. There was a relatively low revision rate, with glenoid loosening and instability being the most common causes. Copyright © 2017 Journal of Shoulder and Elbow Surgery Board of Trustees. Published by Elsevier Inc. All rights reserved.

The revised Multidimensional Model of MAori Identity and Cultural Engagement (MMM-ICE2)

NARCIS (Netherlands)

Houkamau, C.A.; Sibley, C.G.

2015-01-01

We update and validate the revised Multidimensional Model of Māori Identity and Cultural Engagement (MMM-ICE2) by including a seventh Perceived Appearance subscale. The MMM-ICE2 is designed to assess the subjective experiences, efficacy and evaluation of different facets of identity for Māori (the

Revision of the DELFIC Particle Activity Module

Energy Technology Data Exchange (ETDEWEB)

Hooper, David A [ORNL; Jodoin, Vincent J [ORNL

2010-09-01

The Defense Land Fallout Interpretive Code (DELFIC) was originally released in 1968 as a tool for modeling fallout patterns and for predicting exposure rates. Despite the continual advancement of knowledge of fission yields, decay behavior of fission products, and biological dosimetry, the decay data and logic of DELFIC have remained mostly unchanged since inception. Additionally, previous code revisions caused a loss of conservation of radioactive nuclides. In this report, a new revision of the decay database and the Particle Activity Module is introduced and explained. The database upgrades discussed are replacement of the fission yields with ENDF/B-VII data as formatted in the Oak Ridge Isotope Generation (ORIGEN) code, revised decay constants, revised exposure rate multipliers, revised decay modes and branching ratios, and revised boiling point data. Included decay logic upgrades represent a correction of a flaw in the treatment of the fission yields, extension of the logic to include more complex decay modes, conservation of nuclides (including stable nuclides) at all times, and conversion of key variables to double precision for nuclide conservation. Finally, recommended future work is discussed with an emphasis on completion of the overall radiation physics upgrade, particularly for dosimetry, induced activity, decay of the actinides, and fractionation.

Characterization and application of automated in-vacuum PIXE/EBS system for direct analysis of chloride and sulfate ions attack in cementitious materials

Science.gov (United States)

Rihawy, M. S.; Alwazzeh, M.; Abbas, K.

2018-01-01

Ion beam analysis (IBA) techniques (Particle Induced X-ray Emission, PIXE and Elastic Backscattering Spectrometry, EBS), were applied to investigate chloride and sulfate ions diffusion into laboratory prepared mortar samples. Development and characterization of an automated in-vacuum macro PIXE/EBS system is thoroughly discussed. Depth profile information of both chloride and sulfate ions in laboratory prepared mortar samples, after immersion in sea water for nine months, was rapidly and easily obtained at fairly low cost and with standardless analysis, demonstrating the value of the application of IBA to elemental depth profiling in cementitious materials. Chloride and sulfate depth profiles were obtained for two sets of mortar samples, one prepared with different water/cement (W/C) ratios and the other with different sand/cement (S/C) ratios. Results showed higher diffusion rates of both chloride and sulfate ions when both ratios are increased. Additionally, the W/C ratio has a stronger influence in both sulfate and chloride penetration than the S/C ratio, and chloride ions penetrate faster than sulfates. Advantages and limitations of applying IBA techniques in this investigation are discussed. The comparison between PIXE and other X-ray based analytical techniques, namely X-ray fluorescence (XRF) and energy and wavelength dispersive X-rays (EDX/WDX), as well as other traditional wet chemical methods is reviewed, and industrial applications are discussed.

Reference design description for a geologic repository. Revision 02

International Nuclear Information System (INIS)

1999-01-01

This Reference Design Description explains the current design for a potential geologic repository that may be located at Yucca Mountain in Nevada. It describes the proposed design for a surface facility, subsurface repository, and waste packaging; it also presents the current design of the key engineering systems for the final four phases: operations, monitoring, closure, and postclosure. In addition, this Reference Design Description reviews the expected long-term performance of the potential repository. In accordance with current law, this design does not include an interim storage option. This document has six major sections. Section 1 describes the physical layout of the proposed repository. The second section describes the 4-phase evolution of the development of the proposed repository. Section 3 describes the reception of waste from offsite locations. The fourth section details the various systems that will package the waste and move it below ground as well as safety monitoring and closure. Section 5 describes the systems (both physical and analytical) that ensure continued safety after closure. The final section offers design options that may be adopted to increase the margin of safety

Integrating Relational Reasoning and Knowledge Revision during Reading

Science.gov (United States)

Kendeou, Panayiota; Butterfuss, Reese; Van Boekel, Martin; O'Brien, Edward J.

2017-01-01

Our goal in this theoretical contribution is to connect research on knowledge revision and relational reasoning. To achieve this goal, first, we review the "knowledge revision components framework" (KReC) that provides an account of knowledge revision processes, specifically as they unfold during reading of texts. Second, we review a…

The Birth Satisfaction Scale-Revised Indicator (BSS-RI).

Science.gov (United States)

Martin, Colin R; Hollins Martin, Caroline; Redshaw, Maggie

2017-08-29

The current study sought to develop a short birth satisfaction indicator utilising items from the Birth Satisfaction Scale-Revised (BSS-R) for use as a brief measure of birth satisfaction and as a possible key performance indicator for perinatal service delivery evaluation. Building on the recently developed BSS-R, the study aimed to develop a simplified version of the instrument to assess birth satisfaction easily that could work as a short evaluative measure of clinical service delivery for labour and birth that is consistent with policy documents, placing women at the centre of the birth experience. The six item Birth Satisfaction Scale-Revised Indicator (BSS-RI) was embedded within the 2014 National Maternity Survey for England. A random selection of mothers who had given birth in a two week period in England were surveyed three months after the birth. Using a two-stage design and split-half dataset, exploratory factor analysis, confirmatory factor analysis, internal consistency, convergent, divergent and known-groups discriminant validity evaluation were conducted in a secondary analysis of the survey data. Using this large population based survey of recent mothers the short revised measure was found to comprise two distinct domains of birth satisfaction, 'stress and emotional response to labour and birth' and 'quality of care'. The psychometric qualities of the tool were robust as were the indices of validity and reliability evaluated. The BSS-RI represents a short easily administered and scored measure of women's satisfaction with care and the experience of labour and birth. The instrument is potentially useful for researchers, service evaluation and policy makers.

Psychometric Evaluation of the Diabetes Symptom Checklist-Revised (DSC-R)-A Measure of Symptom Distress

NARCIS (Netherlands)

Arbuckle, R.A.; Humphrey, L.; Vardeva, K.; Arondekar, B.; Scott, J.A.; Snoek, F.J.

2009-01-01

Objective: To assess the psychometric validity, reliability, responsiveness, and minimal important differences of the Diabetes Symptoms Checklist-Revised (DSC-R), a widely used patient-reported outcome measure of diabetes symptom distress. Research Design and Methods: Psychometric validity of the

Difficult acetabular revision. A preliminary report.

Science.gov (United States)

Newport, M L; Stuchin, S A; Frankel, V H; Zuckerman, J

1986-01-01

Thirteen patients (14 hips) underwent revision from conventional cemented total hip arthroplasty to uncemented acetabular threaded screw-in components and cementless femoral press-fit stems by means of the Autophor, Biofit, and Ti-Thread designs. The patients suffered from all forms of primary hip disease except rheumatoid arthritis; their average age was 34 years. The average preoperative Harris hip score was 39.4; the average postoperative score was 71.2 at six months, 90.6 at one year, and 91.6 at two years. Complications included two femoral shaft fractures, one femoral nerve palsy, and one dislocation. No signs have been observed of loosening or migration as of an early (6-24 months) follow-up.

EPRI BWR Water Chemistry Guidelines Revision

International Nuclear Information System (INIS)

Garcia, Susan E.; Giannelli, Joseph F.

2014-01-01

BWRVIP-190: BWR Water Chemistry Guidelines – 2008 Revision has been revised. The revision committee consisted of U.S. and non-U.S. utilities (members of the BWR Vessel and Internals Protection (BWRVIP) Mitigation Committee), reactor system manufacturers, fuel suppliers, and EPRI and industry experts. The revised document, BWRVIP-190 Revision 1, was completely reformatted into two volumes, with a simplified presentation of water chemistry control, diagnostic and good practice parameters in Volume 1 and the technical bases in Volume 2, to facilitate use. The revision was developed in parallel and in coordination with preparation of the Fuel Reliability Guidelines Revision 1: BWR Fuel Cladding Crud and Corrosion. Guidance is included for plants operating under normal water chemistry (NWC), moderate hydrogen water chemistry (HWC-M), and noble metal application (GE-Hitachi NobleChem™) plus hydrogen injection. Volume 1 includes significant changes to BWR feedwater and reactor water chemistry control parameters to provide increased assurance of intergranular stress corrosion cracking (IGSCC) mitigation of reactor materials and fuel reliability during all plant conditions, including cold shutdown (≤200°F (93°C)), startup/hot standby (>200°F (93°C) and ≤ 10%) and power operation (>10% power). Action Level values for chloride and sulfate have been tightened to minimize environmentally assisted cracking (EAC) of all wetted surfaces, including those not protected by hydrogen injection, with or without noble metals. Chemistry control guidance has been enhanced to minimize shutdown radiation fields by clarifying targets for depleted zinc oxide (DZO) injection while meeting requirements for fuel reliability. Improved tabular presentations of parameter values explicitly indicate levels at which actions are to be taken and required sampling frequencies. Volume 2 provides the technical bases for BWR water chemistry control for control of EAC, flow accelerated corrosion

40 CFR 60.4124 - Hg budget permit revisions.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Hg budget permit revisions. 60.4124... Coal-Fired Electric Steam Generating Units Permits § 60.4124 Hg budget permit revisions. Except as provided in § 60.4123(b), the permitting authority will revise the Hg Budget permit, as necessary, in...

Effect of Hf Additions to Pt Aluminide Bond Coats on EB-PVD TBC Life

Science.gov (United States)

Nesbitt, James; Nagaraj, Ben; Williams, Jeffrey

2000-01-01

Small Hf additions were incorporated into a Pt aluminide coating during chemical vapor deposition (CVD) on single crystal RENE N5 substrates. Standard yttria-stabilized zirconia top coats were subsequently deposited onto the coated substrates by electron beam-physical vapor deposition (EB-PVD). The coated substrates underwent accelerated thermal cycle testing in a furnace at a temperature in excess of 1121 C (2050 F) (45 minute hot exposure, 15 minute cool to approximately 121 C (250 F)) until the thermal barrier coating (TBC) failed by spallation. Incorporating Hf in the bond coat increased the TBC life by slightly more than three times that of a baseline coating without added Hf. Scanning electron microscopy of the spalled surfaces indicated that the presence of the Hf increased the adherence of the thermally grown alumina to the Pt aluminide bond coat. The presence of oxide pegs growing into the coating from the thermally grown alumina may also partially account for the improved TBC life by creating a near-surface layer with a graded coefficient of thermal expansion.

Ice bridges and ridges in the Maxwell-EB sea ice rheology

Directory of Open Access Journals (Sweden)

V. Dansereau

2017-09-01

Full Text Available This paper presents a first implementation of a new rheological model for sea ice on geophysical scales. This continuum model, called Maxwell elasto-brittle (Maxwell-EB, is based on a Maxwell constitutive law, a progressive damage mechanism that is coupled to both the elastic modulus and apparent viscosity of the ice cover and a Mohr–Coulomb damage criterion that allows for pure (uniaxial and biaxial tensile strength. The model is tested on the basis of its capability to reproduce the complex mechanical and dynamical behaviour of sea ice drifting through a narrow passage. Idealized as well as realistic simulations of the flow of ice through Nares Strait are presented. These demonstrate that the model reproduces the formation of stable ice bridges as well as the stoppage of the flow, a phenomenon occurring within numerous channels of the Arctic. In agreement with observations, the model captures the propagation of damage along narrow arch-like kinematic features, the discontinuities in the velocity field across these features dividing the ice cover into floes, the strong spatial localization of the thickest, ridged ice, the presence of landfast ice in bays and fjords and the opening of polynyas downstream of the strait. The model represents various dynamical behaviours linked to an overall weakening of the ice cover and to the shorter lifespan of ice bridges, with implications in terms of increased ice export through narrow outflow pathways of the Arctic.

Ice bridges and ridges in the Maxwell-EB sea ice rheology

Science.gov (United States)

Dansereau, Véronique; Weiss, Jérôme; Saramito, Pierre; Lattes, Philippe; Coche, Edmond

2017-09-01

This paper presents a first implementation of a new rheological model for sea ice on geophysical scales. This continuum model, called Maxwell elasto-brittle (Maxwell-EB), is based on a Maxwell constitutive law, a progressive damage mechanism that is coupled to both the elastic modulus and apparent viscosity of the ice cover and a Mohr-Coulomb damage criterion that allows for pure (uniaxial and biaxial) tensile strength. The model is tested on the basis of its capability to reproduce the complex mechanical and dynamical behaviour of sea ice drifting through a narrow passage. Idealized as well as realistic simulations of the flow of ice through Nares Strait are presented. These demonstrate that the model reproduces the formation of stable ice bridges as well as the stoppage of the flow, a phenomenon occurring within numerous channels of the Arctic. In agreement with observations, the model captures the propagation of damage along narrow arch-like kinematic features, the discontinuities in the velocity field across these features dividing the ice cover into floes, the strong spatial localization of the thickest, ridged ice, the presence of landfast ice in bays and fjords and the opening of polynyas downstream of the strait. The model represents various dynamical behaviours linked to an overall weakening of the ice cover and to the shorter lifespan of ice bridges, with implications in terms of increased ice export through narrow outflow pathways of the Arctic.

Final Report: Conceptual Design of an Electron Accelerator for Bio-Solid Waste Treatment

Energy Technology Data Exchange (ETDEWEB)

Cooper, Charles [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States)

2017-09-20

Several studies have identified electron beam (EB) irradiation of municipal wastewater and bio-solids as an effective and promising approach to the environmental remediation of the enormous quantities of human waste created by a growing world-wide population and increased urbanization. However, despite the technical success of experimental and pilot programs over the last several decades, the technique is still not in commercial use anywhere in the world. In addition, the report also identifies the need for “Financial and infrastructure participation from a utility for demonstration project” and “Education and awareness of safety of utilizing electron beam technology” as two additional roadblocks preventing technology adoption of EB treatment for bio-solids. In this concept design, we begin to address these barriers by working with Metropolitan Water Reclamation District of Greater Chicago (MWRD) and by the applying the latest accelerator technologies developed at Fermilab and within the DOE Office of Science laboratory complex.

Design basis ground motion (Ss) required on new regulatory guide

International Nuclear Information System (INIS)

Kamae, Katsuhiro

2013-01-01

New regulatory guide is enforced on July 8. Here, it is introduced how the design basis ground motion (Ss) for seismic design of nuclear power reactor facilities was revised on the new guide. Ss is formulated as two types of earthquake ground motions, earthquake ground motions with site specific earthquake source and with no such specific source locations. The latter is going to be revised based on the recent observed near source ground motions. (author)

[Conception and implementation of a novel E-learning module with EbM learning contents in operative dentistry].

Science.gov (United States)

Gerhardt-Szép, Susanne; Dreher, Stefanie; Rüttermann, Stefan; Weberschock, Tobias

2017-11-01

Computer-assisted learning (CAL) programs are becoming more widely used in medical and dental training. However, the combination of CAL programs and evidence-based education in dentistry has not been described previously. The aim was to determine the acceptance and user-friendliness of a CAL program combined with evidence-based training. The didactic concept of the module includes the case-oriented, problem-based embedding of a total of 32 EbM learning assignments, which can be completed interactively and self-determinedly in an interdisciplinary context using focus patients with different diseases. The present study was conducted at the Dental School of the Goethe University in Frankfurt/Main. Data on acceptance and user-friendliness were collected from three consecutive cohorts of 114 dental students attending their first clinical semester. They used the "Toothache Walk-in Clinic: FOCUS" CAL, which can be downloaded via the Internet. The instrument consisted of 64 statements. The first part addressed general information about the user. The second part contained 43 specific statements on the CAL program. These included factors A (handling and technical aspects), B (content and functional range), and C (didactics and suitability for education). Possible responses ranged from 0 to 3 (0 = strongly disagree, 3 = strongly agree). All of the 114 questionnaires distributed were returned (response rate 100%). Most users (90.1%) considered the topics of evidence-based dentistry important for their training. They rated the program by using German school grades, and the overall rating was 2.26 (SD = 0.64). Most students (88.6%) considered the program useful for their clinical training in the treatment of patients. The mean scores for the 43 specific items amounted to 1.90 (factor A, SD = 0.63), 1.55 (factor B, SD = 1.93), and 2.23 (factor C, SD = 0.79). The CAL program with dental medicine vignettes and learning elements for evidence-based medicine received a primarily

EMI filter design

CERN Document Server

Ozenbaugh, Richard Lee

2011-01-01

With today's electrical and electronics systems requiring increased levels of performance and reliability, the design of robust EMI filters plays a critical role in EMC compliance. Using a mix of practical methods and theoretical analysis, EMI Filter Design, Third Edition presents both a hands-on and academic approach to the design of EMI filters and the selection of components values. The design approaches covered include matrix methods using table data and the use of Fourier analysis, Laplace transforms, and transfer function realization of LC structures. This edition has been fully revised

A taxonomic revision of the genus Podocarpus

OpenAIRE

Laubenfels, de, D.J.

1985-01-01

In connection with the forthcoming revision of the Coniferae for the Flora Malesiana, the author thought it necessary to revise the genus Podocarpus. Although this genus has a substantial representation in Malesia (30 species), the revision is too involved to be appropriate with the Flora Malesiana per se. One new subgenus and 17 new sections are described, and 94 species are enumerated, of which 11 species and 1 variety are described as new, and 3 varieties have been raised to specific rank....

Design Patterns Application in the ERP Systems Improvements

Science.gov (United States)

Jovičić, Bojan; Vlajić, Siniša

Design patterns application have long been present in software engineering. The same is true for ERP systems in business software. Is it possible that ERP systems do not have a good maintenance score? We have found out that there is room for maintenance improvement and that it is possible to improve ERP systems using design patterns. We have conducted comparative analysis of ease of maintenance of the ERP systems. The results show that the average score for our questions is 64%, with most answers for ERP systems like SAP, Oracle EBS, Dynamics AX. We found that 59% of ERP system developer users are not familiar with design patterns. Based on this research, we have chosen Dynamics AX as the ERP system for examination of design patterns improvement possibilities. We used software metrics to measure improvement possibility. We found that we could increase the Conditional Complexity score 17-fold by introducing design patterns.

Revised Human Health Risk Assessment on Chlorpyrifos

Science.gov (United States)

We have revised our human health risk assessment and drinking water exposure assessment for chlorpyrifos that supported our October 2015 proposal to revoke all food residue tolerances for chlorpyrifos. Learn about the revised analysis.

REVISION PERMISSIABILITY IN CIVIL PROCEDURE IN REPUBLIC OF MACEDONIA

Directory of Open Access Journals (Sweden)

Marina Gligorova

2015-04-01

Full Text Available The revision as an extraordinary legal remedy is one more legal instrument for litigant in the effort to achieve protection of the rights or to defend against ungrounded claims of the other party. Litigants may declare revision of the litigation process due to substantive violations of the provisions of Civil Procedure and incorrect application of substantive law. Declaring revision because of a substantive violation of the provisions of Civil Procedure is limited. The purpose of this research paper is to investigate the most common reasons for filing revision of the litigation process in the period from June 2011 to June in 2012. The research includes what kind of reasons are often repeated, and the volume, or the number of reviews submitted to the Supreme Court of the Republic of Macedonia. As general hypothesis is that most of the adopted revisions are due to substantial violations of the provisions of civil procedure. Two-thirds of the stated revisions in front of the Supreme Court of Republic of Macedonia were rejected as unfounded and only one third of the submitted revisions from June 2011 to June 2012 were grounded. Since accepted revisions 59% due to incorrect application of substantive law, and 41% due to substantial violations of the provisions of Civil Procedure.

Design of a hybrid reconfigurable Software Defined Radio transceiver based on frequency shift keying using multiple encoding schemes

Directory of Open Access Journals (Sweden)

Nikhil Marriwala

2016-03-01

The aim of this paper was to analyze Frequency Shift Keying (FSK Transceiver built using Laboratory Virtual Instrumentation Engineering Workbench (LabVIEW and to measure the reduction in data errors in the presence of Forward Error Correction (FEC channel coding algorithms namely the Convolution and the Turbo Codes. Through this design a graphical representation of Bit Error Rate (BER vs Eb/N0 where (Eb is Energy per bit and (N0 is Spectral noise density has been given in the presence of Additive White Gaussian Noise (AWGN introduced in the channel. FSK is widely used for data transmission over band pass channels; hence, we have chosen FSK for the implementation of SDR. The SDR transceiver module designed has been fully implemented and has the ability to navigate over a wide range of frequencies with programmable channel bandwidth and modulation characteristics. We are able to build an interactive FSK based SDR transceiver in a shorter time with the use of LabVIEW. The outputs achieved show a low BER for very high data rates in the presence of AWGN noise.

Revised concept for the Waste Isolation Pilot Plant

International Nuclear Information System (INIS)

Dennis, A.W.; Milloy, J.A.; Scully, L.W.; Shefelbine, H.C.; Stinebaugh, R.E.; Wowak, W.E.

1978-07-01

The quantities of remotely handled wastes that must be handled at the Waste Isolation Pilot Plant have been reduced from 250 x 10 3 ft 3 /y to 10 x 10 3 ft 3 /y; the capital cost of the facility will be reduced from 534 to 428 million dollars. Changes in the facility design due to the reduction in the amount of remote-handled waste are discussed. If DOE should exercise its option to construct a high-level waste repository concurrently with the construction of the revised design, with both facilities receiving waste in 1985, the combined cost would be about 580 million dollars. However, it is unlikely that significant quantities of high-level waste in a form suitable for geologic disposal would be available until after 1990. (13 figures, 5 tables)

Development of structure design program for venturi scrubber working at self-priming mode

International Nuclear Information System (INIS)

Wang Meng; Sun Zhongning; Gu Haifeng

2012-01-01

A structure design program was developed for Venturi scrubber working at the self-priming mode. This program proposed a complete logic for thermal parameters calculation and structure design of the throat. A revised calculation for resistance relationship was carried out based on experimental study. The relative error between revised results and experimental values is within 8.6%. (authors)

Test-Retest Reliability of the Parent Behavior Importance Questionnaire-Revised and the Parent Behavior Frequency Questionnaire-Revised

Science.gov (United States)

Mowder, Barbara A.; Shamah, Renee

2011-01-01

This study evaluated the test-retest reliability of two parenting measures: the Parent Behavior Importance Questionnaire-Revised (PBIQ-R) and Parent Behavior Frequency Questionnaire-Revised (PBFQ-R). These self-report parenting behavior assessment measures may be utilized as pre- and post-parent education program measures, with parents as well as…

Maximum surgical blood ordering schedules for revision lower limb arthroplasty.

Science.gov (United States)

Mahadevan, Devendra; Challand, Christopher; Clarke, Andrew; Keenan, Jonathan

2011-05-01

Effective utilisation of blood products is fundamental. The introduction of maximum surgical blood ordering schedules (MSBOS) for operations has been shown to improve transfusion services. A retrospective analysis was undertaken to establish an evidence-based MSBOS for revision total hip replacement (THR) and total knee revision (TKR). The impact of this schedule on blood conservation was analysed. A retrospective analysis was undertaken on 397 patients who underwent revision THR and TKR over a 4-year period. The cross-match-to-transfusion ratio (CTR) and transfusion index (TI) were calculated. A MSBOS protocol was created based on the TIs and its' impact on transfusion services was assessed prospectively on 125 patients by comparing CTRs. In revision THR, TI was 1.19 for elective cases, 1.55 for emergency cases and 2.35 for infected cases. There was no difference in TI for revisions of cemented and uncemented components. Single component THR revision required less transfusion. In revision TKR, TI was 0.31 for elective cases, 2.0 for emergency cases and 1.23 for cases with infection. The introduction of the MSBOS protocol had resulted in a considerable improvement in blood ordering. Reductions in the CTR were seen for all types of revision surgery, but most evident in elective revision THR (3.24-2.18) and elective revision TKR (7.95-1.2). Analysis confirmed that excessive cross-matching occurred for revision lower limb arthroplasty. The introduction of our MSBOS protocol promoted blood conservation and compliance with established national guidelines.

Risk factors for total hip arthroplasty aseptic revision.

Science.gov (United States)

Khatod, Monti; Cafri, Guy; Namba, Robert S; Inacio, Maria C S; Paxton, Elizabeth W

2014-07-01

The purpose of this study was to evaluate patient, operative, implant, surgeon, and hospital factors associated with aseptic revision after primary THA in patients registered in a large US Total Joint Replacement Registry. A total of 35,960 THAs registered from 4/2001-12/2010 were evaluated. The 8-year survival rate was 96.7% (95% CI 96.4%-97.0%). Females had a higher risk of aseptic revision than males. Hispanic and Asian patients had a lower risk of revision than white patients. Ceramic-on-ceramic, ceramic-on-conventional polyethylene, and metal-on-conventional polyethylene bearing surfaces had a higher risk of revision than metal-on-highly cross-linked polyethylene. Body mass index, health status, diabetes, diagnosis, fixation, approach, bilateral procedures, head size, surgeon fellowship training, surgeon and hospital volume were not revision risk factors. Copyright © 2014 Elsevier Inc. All rights reserved.

Activity Management System user reference manual. Revision 1

International Nuclear Information System (INIS)

Gates, T.A.; Burdick, M.B.

1994-01-01

The Activity Management System (AMS) was developed in response to the need for a simple-to-use, low-cost, user interface system for collecting and logging Hanford Waste Vitrification Plant Project (HWVP) activities. This system needed to run on user workstations and provide common user access to a database stored on a local network file server. Most important, users wanted a system that provided a management tool that supported their individual process for completing activities. Existing system treated the performer as a tool of the system. All AMS data is maintained in encrypted format. Users can feel confident that any activities they have entered into the database are private and that, as the originator, they retain sole control over who can see them. Once entered into the AMS database, the activities cannot be accessed by anyone other than the originator, the designated agent, or by authorized viewers who have been explicitly granted the right to look at specific activities by the originator. This user guide is intended to assist new AMS users in learning how to use the application and, after the initial learning process, will serve as an ongoing reference for experienced users in performing infrequently used functions. Online help screens provide reference to some of the key information in this manual. Additional help screens, encompassing all the applicable material in this manual, will be incorporated into future AMS revisions. A third, and most important, source of help is the AMS administrator(s). This guide describes the initial production version of AMS, which has been designated Revision 1.0

Practical lighting design with LEDs

CERN Document Server

Lenk, Ron

2016-01-01

The second edition of Practical Lighting Design with LEDs has been revised and updated to provide the most current information for developing light-emitting diodes products. The authors, noted authorities in the field, offer a review of the most relevant topics including optical performance, materials, thermal design, and modeling and measurement. Comprehensive in scope, the text covers all the information needed to design LEDs into end products.

Design Package for Fuel Retrieval System Fuel Handling Tool Modification

International Nuclear Information System (INIS)

TEDESCHI, D.J.

2000-01-01

This design package documents design, fabrication, and testing of new stinger tool design. Future revisions will document further development of the stinger tool and incorporate various developmental stages, and final test results

78 FR 7703 - Revisions to the California State Implementation Plan, South Coast Air Quality Management...

Science.gov (United States)

2013-02-04

... the California State Implementation Plan, South Coast Air Quality Management District, Proposed Rule... approve a revision to the South Coast Air Quality Management District (SCAQMD) portion of the California... digesters. Rule 1127 was designed to implement the 2003 Air Quality Management Plan (AQMP) control measure...

The New Federal Wage-Hour, Equal Pay, and Equal Employment Opportunity Laws. Including 1974 Revisions.

Science.gov (United States)

Institute For Management, Old Saybrook, CT.

The book is designed to explain the entire Fair Labor Standards Act. The 1974 amendments are detailed regarding new and previously covered employees, agricultural labor, government employees, domestics, conglomerates, small stores, other revisions, overtime exemptions, and age discrimination. The document elaborates on specifications for overtime…

78 FR 35719 - Endangered and Threatened Wildlife and Plants; Proposed Revision To the Nonessential Experimental...

Science.gov (United States)

2013-06-13

... governing the Mexican wolf nonessential experimental population designation. Background Our approach in this... private activities within or adjacent to the experimental population area. Furthermore, as set forth in 50...; Proposed Revision To the Nonessential Experimental Population of the Mexican Wolf AGENCY: Fish and Wildlife...

Revision of infected knee arthroplasties in Denmark

DEFF Research Database (Denmark)

Lindberg-Larsen, Martin; Jørgensen, Christoffer C; Bagger, Jens

2016-01-01

Background and purpose - The surgical treatment of periprosthetic knee infection is generally either a partial revision procedure (open debridement and exchange of the tibial insert) or a 2-stage exchange arthroplasty procedure. We describe the failure rates of these procedures on a nationwide...... basis. Patients and methods - 105 partial revisions (100 patients) and 215 potential 2-stage revision procedures (205 patients) performed due to infection from July 1, 2011 to June 30, 2013 were identified from the Danish Knee Arthroplasty Register (DKR). Failure was defined as surgically related death...

75 FR 60485 - NRC Enforcement Policy Revision

Science.gov (United States)

2010-09-30

... NUCLEAR REGULATORY COMMISSION [NRC-2008-0497] NRC Enforcement Policy Revision AGENCY: Nuclear Regulatory Commission. ACTION: Policy statement. SUMMARY: The Nuclear Regulatory Commission (NRC or Commission) is publishing a major revision to its Enforcement Policy (Enforcement Policy or Policy) to...

[Revised practice guideline 'Anaemia in midwifery practice'

NARCIS (Netherlands)

Beentjes, M.; Jans, S.M.P.J.

2012-01-01

The practice guideline of the Royal Dutch Organization of Midwives 'Anaemia in primary care midwifery practice' published in 2000, has recently been revised. The revised guideline takes physiological haemodilution during pregnancy into consideration and provides gestation specific reference values

Analysis of NRC Regulatory Guide 1.21 Revision 2

Energy Technology Data Exchange (ETDEWEB)

Kim, Sung Il; Yook, Dae Sik; Lee, Byung Soo [KINS, Daejeon (Korea, Republic of)

2015-05-15

It is essential to have a degree of uniformity in the methods used for measuring, evaluating, recording, and reporting data on radioactive material in effluents and solid wastes. For this purpose, the U.S. Nuclear Regulatory Commission (NRC) released a revised version of the Regulatory Guide 1.21 'Measuring, evaluating, and reporting radioactive material in liquid and gaseous effluents and solid waste' (revision 2) in 2009, updating the revision 1 version released in 1974. This study compares the previous revision 1 (1974) version with the revision 2 (2009) version to elaborate on the application of the guidelines to Korea. This study consists of an analysis of the 2009 Revision 2 version of the U.S. NRC Regulatory Guidelines 1.21 and an exposition of methods for its application in the domestic environment. Major revisions were made to allow for the adoption of a risk informed approach. Radionuclides with lower than 1% contribution to emission or radiation levels can be selected as principal radionuclides. Requirements for analysis of leaks and spills have been reinforced, with additional groundwater monitoring and hydrological data analysis becoming necessary.

Description of the rates, trends and surgical burden associated with revision for prosthetic joint infection following primary and revision knee replacements in England and Wales: an analysis of the National Joint Registry for England, Wales, Northern Ireland and the Isle of Man.

Science.gov (United States)

Lenguerrand, Erik; Whitehouse, Michael R; Beswick, Andrew D; Toms, Andrew D; Porter, Martyn L; Blom, Ashley W

2017-07-10

To describe the prevalence rates of revision surgery for the treatment of prosthetic joint infection (PJI) for patients undergoing knee replacement, their time trends, the cumulative incidence function of revision for PJI and estimate the burden of PJI at health service level. We analysed revision knee replacements performed due to a diagnosis of PJI and the linked index procedures recorded in the National Joint Registry from 2003 to 2014 for England and Wales. The cohort analysed consisted of 679 010 index primary knee replacements, 33 920 index revision knee replacements and 8247 revision total knee replacements performed due to a diagnosis of PJI. The prevalence rates, their time trends investigated by time from index surgery to revision for PJI, cumulative incidence functions and the burden of PJI (total procedures) were calculated. Overall linear trends were investigated with log-linear regression. The incidence of revision total knee replacement due to PJI at 2 years was 3.2/1000 following primary and 14.4/1000 following revision knee replacement, respectively. The prevalence of revision due to PJI in the 3 months following primary knee replacement has risen by 2.5-fold (95% CI 1.2 to 5.3) from 2005 to 2013 and 7.5-fold (95% CI 1.0 to 56.1) following revision knee replacement. Over 1000 procedures per year are performed as a consequence of knee PJI, an increase of 2.8 from 2005 to 2013. Overall, 75% of revisions were two-stage with an increase in use of single-stage from 7.9% in 2005 to 18.8% in 2014. Although the risk of revision due to PJI following knee replacement is low, it is rising, and coupled with the established and further predicted increased incidence of both primary and revision knee replacements, this represents an increasing and substantial treatment burden for orthopaedic service delivery in England and Wales. This has implications for future service design and the funding of individual and specialist centres. © Article author

Nuclear power plant design characteristics. Structure of nuclear power plant design characteristics in the IAEA Power Reactor Information System (PRIS)

International Nuclear Information System (INIS)

2007-03-01

One of the IAEA's priorities has been to maintain the Power Reactor Information System (PRIS) database as a viable and useful source of information on nuclear reactors worldwide. To satisfy the needs of PRIS users as much as possible, the PRIS database has included also a set of nuclear power plant (NPP) design characteristics. Accordingly, the PRIS Technical Meeting, organized in Vienna 4-7 October 2004, initiated a thorough revision of the design data area of the PRIS database to establish the actual status of the data and make improvements. The revision first concentrated on a detailed review of the design data completion and the composition of the design characteristics. Based on the results of the review, a modified set and structure of the unit design characteristics for the PRIS database has been developed. The main objective of the development has been to cover all significant plant systems adequately and provide an even more comprehensive overview of NPP unit designs stored in the PRIS database

Belief Revision in the GOAL Agent Programming Language

DEFF Research Database (Denmark)

Spurkeland, Johannes Svante; Jensen, Andreas Schmidt; Villadsen, Jørgen

2013-01-01

Agents in a multiagent system may in many cases find themselves in situations where inconsistencies arise. In order to properly deal with these, a good belief revision procedure is required. This paper illustrates the usefulness of such a procedure: a certain belief revision algorithm is consider...... in order to deal with inconsistencies and, particularly, the issue of inconsistencies, and belief revision is examined in relation to the GOAL agent programming language....

Current Epidemiology of Revision Total Knee Arthroplasty in the United States.

Science.gov (United States)

Delanois, Ronald E; Mistry, Jaydev B; Gwam, Chukwuweike U; Mohamed, Nequesha S; Choksi, Ujval S; Mont, Michael A

2017-09-01

Revision surgery for failed total knee arthroplasty (TKA) continues to pose a substantial burden for the United States healthcare system. The predominant etiology of TKA failure has changed over time and may vary between studies. This report aims to update the current literature on this topic by using a large national database. Specifically, we analyzed: (1) etiologies for revision TKA; (2) frequencies of revision TKA procedures; (3) various demographics including payer type and region; and (4) the length of stay (LOS) and total charges based on type of revision TKA procedure. The Healthcare Cost and Utilization Project (HCUP) National Inpatient Sample (NIS) database was used to identify all revision TKA procedures performed between 2009 and 2013. Clinical, economic, and demographic data were collected and analyzed for 337,597 procedures. Patients were stratified according to etiology of failure, age, sex, race, US census region, and primary payor class. The mean LOS and total charges were also calculated. Infection was the most common etiology for revision TKA (20.4%), closely followed by mechanical loosening (20.3%). The most common revision TKA procedure performed was all component revision (31.3%). Medicare was the primary payor for the greatest proportion of revisions (57.7%). The South census region performed the most revision TKAs (33.2%). The overall mean LOS was 4.5 days, with arthrotomy for removal of prosthesis without replacement procedures accounting for the longest stays (7.8 days). The mean total charge for revision TKAs was $75,028.07. Without appropriate measures in place, the burden of revision TKAs may become overwhelming and pose a strain on providers and institutions. Continued insight into the etiology and epidemiology of revision TKAs may be the principle step towards improving outcomes and mitigating the need for future revisions. Copyright © 2017 Elsevier Inc. All rights reserved.

Planned revision to DOE Order 5820.2A, Radioactive Waste Management

Energy Technology Data Exchange (ETDEWEB)

Duggan, G.J. [Dept. of Energy, Washington, DC (United States); Williams, R.E.; Kudera, D.E. [EG and G Idaho, Inc., Idaho Falls, ID (United States). Idaho National Engineering Lab.; Bailey, D.E. [NJG, Inc. (United States)

1993-03-01

US Department of Energy Headquarters initiated efforts to revise DOE Order 5820.2A, ``Radioactive Waste Management``. The purpose of the revision is to enhance DOE waste management requirements, reflect new DOE organizational responsibilities, and consolidate requirements for management of all waste, under the responsibility of Environmental Restoration and Waste Management, into a single order. This paper discusses the revision philosophy, objectives of the revision, and strategy for the revision. Issues being considered for inclusion in the revision and recommended methods of resolving each issue are also discussed.

Descriptor revision belief change through direct choice

CERN Document Server

Hansson, Sven Ove

2017-01-01

This book provides a critical examination of how the choice of what to believe is represented in the standard model of belief change. In particular the use of possible worlds and infinite remainders as objects of choice is critically examined. Descriptors are introduced as a versatile tool for expressing the success conditions of belief change, addressing both local and global descriptor revision. The book presents dynamic descriptors such as Ramsey descriptors that convey how an agent’s beliefs tend to be changed in response to different inputs. It also explores sentential revision and demonstrates how local and global operations of revision by a sentence can be derived as a special case of descriptor revision. Lastly, the book examines revocation, a generalization of contraction in which a specified sentence is removed in a process that may possibly also involve the addition of some new information to the belief set.

Impact of revisions to the F-Tag 309 surveyors' interpretive guidelines on pain management among nursing home residents.

Science.gov (United States)

Lapane, Kate L; Quilliam, Brian J; Chow, Wing; Kim, Myoung S

2012-05-01

On 31 March 2009, the US Centers for Medicare & Medicaid Services (CMS) provided revised guidance for meeting compliance in the evaluation and management of pain in nursing home residents, known as F-Tag 309. The aim of the study was to estimate the extent to which implementation of revisions to the surveyors' interpretive guidelines for F-Tag 309 improved recognition and management of pain among nursing home residents. The impact of the revisions to guidance on F-Tag 309 on pain in nursing home residents was investigated. The study was quasi-experimental in design and included 174 for-profit nursing homes in 19 US states. Nursing home residents with ≥2 Minimum Data Set (MDS) assessments between 1 January 2007 and 30 March 2009 (before the revisions to the guidelines; n = 8449) and between 31 March 2009 and 31 December 2009 (after the revisions; n = 1400) were included. The MDS assessments provided information on pain, analgesic use and cognitive, functional and emotional status. Separate logistic regression models that adjusted for clustering effects of residents residing in nursing homes provided estimates of the relationship between the implementation of the revisions to F-Tag 309 and the prevalence of pain and its management. Pain was more likely to be documented in the period after the revisions were implemented. The odds of pain being documented on at least one of two consecutive MDS assessments increased after the revisions to the guidelines were implemented (adjusted odds ratio [OR] 1.15; 95% confidence interval [CI] 1.01, 1.31). Increases in scheduled analgesic prescription were observed in the post-revision era (adjusted OR 1.38; 95% CI 1.21,1.57). The implementation of revisions to the surveyors' interpretive guidelines for F-Tag 309 improved recognition and management of pain as well as analgesic use in nursing home residents with documented non-cancer pain. Use of directed language as part of the surveyors' interpretive guidelines may be a

Deep prosthetic joint infection: a qualitative study of the impact on patients and their experiences of revision surgery

Science.gov (United States)

Blom, Ashley W; Whitehouse, Michael R; Gooberman-Hill, Rachael

2015-01-01

Objectives Around 1% of patients who have a hip replacement have deep prosthetic joint infection (PJI) afterwards. PJI is often treated with antibiotics plus a single revision operation (1-stage revision), or antibiotics plus a 2-stage revision process involving more than 1 operation. This study aimed to characterise the impact and experience of PJI and treatment on patients, including comparison of 1-stage with 2-stage revision treatment. Design Qualitative semistructured interviews with patients who had undergone surgical revision treatment for PJI. Patients were interviewed between 2 weeks and 12 months postdischarge. Data were audio-recorded, transcribed, anonymised and analysed using a thematic approach, with 20% of transcripts double-coded. Setting Patients from 5 National Health Service (NHS) orthopaedic departments treating PJI in England and Wales were interviewed in their homes (n=18) or at hospital (n=1). Participants 19 patients participated (12 men, 7 women, age range 56–88 years, mean age 73.2 years). Results Participants reported receiving between 1 and 15 revision operations after their primary joint replacement. Analysis indicated that participants made sense of their experience through reference to 3 key phases: the period of symptom onset, the treatment period and protracted recovery after treatment. By conceptualising their experience in this way, and through themes that emerged in these periods, they conveyed the ordeal that PJI represented. Finally, in light of the challenges of PJI, they described the need for support in all of these phases. 2-stage revision had greater impact on participants’ mobility, and further burdens associated with additional complications. Conclusions Deep PJI impacted on all aspects of patients’ lives. 2-stage revision had greater impact than 1-stage revision on participants’ well-being because the time in between revision procedures meant long periods of immobility and related psychological distress

The Self-Concept. Volume 1, A Review of Methodological Considerations and Measuring Instruments. Revised Edition.

Science.gov (United States)

Wylie, Ruth C.

This volume of the revised edition describes and evaluates measurement methods, research designs, and procedures which have been or might appropriately be used in self-concept research. Working from the perspective that self-concept or phenomenal personality theories can be scientifically investigated, methodological flaws and questionable…

Multilayer stacks obtained by ion assisted EB PVD aimed at thermal barrier coating

Energy Technology Data Exchange (ETDEWEB)

Roos, E.; Maile, K.; Lyutovich, A. [Stuttgart Univ. (DE). Materialpruefungsanstalt (MPA)

2010-07-01

Thermal Barrier Coating (TBC) using Electron Beam Physical Vapour Deposition (EB PVD) is widely implemented, especially for aero-engine turbine blades. Generally, multilayer stacks are used for these aims. For the additional improvement of intermediate layers with graded transitions to the initial Ni-based alloy, the use of accelerated ions in the EBPVD-process is advantageous. The effect of the substrate bias potential, ion current density and deposition temperature on the structure and properties of Ti and Zr intermediate layers are investigated. The morphology of the films is studied using optical microscopy, scanning electron microscopy (SEM) and atomic force microscopy (AFM). It is found that the surface morphology becomes smoother with rising bias potential and decreasing ion current density. Measurements of Vicker's micro-hardness performed on these coatings have shown its increase with higher values of the bias and its reduction with the growing temperature. This effect is caused by the observed decrease in grain size and higher porosity of the films. A multilayer coating system Ni (based substrate)-Si-Si{sub x}Al{sub y}-Al with graded transitions between the layers is obtained using ion assisted EBPVD. Architecture of a multilayer stack for TBC with graded transitions is proposed. (orig.)

A Revision of the genus Ceratogyrus Pocock (Araneae: Theraphosidae

Directory of Open Access Journals (Sweden)

J.I. De Wet

1991-09-01

Full Text Available The African genus Ceratogyrus of the family Theraphosidae is revised, with notes of its natural history. Seven species are recognised and distinguished in a key. Six species, namely C. bechuanicus Pocock, C. brachycephalus Hewitt, C. darlingii Pocock, C. dolichocephalus Hewitt, C. marshalli Pocock and C. sanderi Strand are redescribed and figured, C. cornuatus is newly described and figured and C. schultzei Pocock is synonymized with C. bechuanicus. Lectotypes are designated for four species namely, C. brachycephalus, C. darlingii, C. dolichocephalus and C. marshalli. Distributional data is given for all seven species.

Evaluation of Students’ Perceptions Towards An Innovative Teaching-Learning Method During Pharmacology Revision Classes: Autobiography of Drugs

Science.gov (United States)

Ganjiwale, Jaishree

2015-01-01

Introduction Various studies in medical education have shown that active learning strategies should be incorporated into the teaching–learning process to make learning more effective, efficient and meaningful. Objectives The aim of this study was to evaluate student’s perceptions on an innovative revision method conducted in Pharmacology i.e. in form of Autobiography of Drugs. The main objective of study was to help students revise the core topics in Pharmacology in an interesting way. Settings and Design Questionnaire based survey on a newer method of pharmacology revision in two batches of second year MBBS students of a tertiary care teaching medical college. Materials and Methods Various sessions on Autobiography of Drugs were conducted amongst two batches of second year MBBS students, during their Pharmacology revision classes. Student’s perceptions were documented with the help of a five point likert scale through a questionnaire regarding quality, content and usefulness of this method. Statistical analysis used Descriptive analysis. Results Students of both the batches appreciated the innovative method taken up for revision. The median scores in most of the domains in both batches were four out of five, indicative of good response. Feedback from open-ended questions also revealed that the innovative module on “Autobiography of Drugs” was taken as a positive learning experience by students. Conclusions Autobiography of drugs has been used to help students recall topics that they have learnt through other teachings methods. Autobiography sessions in Pharmacology during revision slots, can be one of the interesting ways in helping students revise and recall topics which have already been taught in theory classes. PMID:26393138

Explanatory Coherence and Belief Revision in Naive Physics

Science.gov (United States)

1988-07-01

continental drift (Thagard & Nowak, 1988), and debates about why the dinosaurs became extinct . Application of ECHO to the belief revisions in Pat and Hal...rewono of nocuamy Idid 4onoly by bodck number) Students of reasoning have long tried to understand how people revise systems of beliefs. We maintain...Princeton University Students of reasoning have long tried to understand how people revise systems of beliefs (see Wertheimer, 1945, for example). We will

CDMS: CAD data set system design description. Revision 1

International Nuclear Information System (INIS)

Gray, E.L.

1994-01-01

This document is intended to formalize the program design of the CAD Data Set Management System (CDMS) and to be the vehicle to communicate the design to the Engineering, Design Services, and Configuration Management organizations and the WHC IRM Analysts/Programmers. The SDD shows how the software system will be structured to satisfy the requirements identified in the WHC-SD-GN-CSRS-30005 CDMS Software Requirement Specification (SRS). It is a description of the software structure, software components, interfaces, and data that make up the CDMS System. The design descriptions contained within this document will describe in detail the software product that will be developed to assist the aforementioned organizations for the express purpose of managing CAD data sets associated with released drawings, replacing the existing locally developed system and laying the foundation for automating the configuration management

RFID design principles

CERN Document Server

Lehpamer, Harvey

2012-01-01

This revised edition of the Artech House bestseller, RFID Design Principles, serves as an up-to-date and comprehensive introduction to the subject. The second edition features numerous updates and brand new and expanded material on emerging topics such as the medical applications of RFID and new ethical challenges in the field. This practical book offers you a detailed understanding of RFID design essentials, key applications, and important management issues. The book explores the role of RFID technology in supply chain management, intelligent building design, transportation systems, military

New development for low energy electron beam processor

International Nuclear Information System (INIS)

Takei, Taro; Goto, Hitoshi; Oizumi, Matsutoshi; Hirakawa, Tetsuya; Ochi, Masafumi

2003-01-01

Newly developed low-energy electron beam (EB) processors that have unique designs and configurations compared to conventional ones enable electron-beam treatment of small three-dimensional objects, such as grain-like agricultural products and small plastic parts. As the EB processor can irradiate the products from the whole angles, the uniform EB treatment can be achieved at one time regardless the complex shapes of the product. Here presented are two new EB processors: the first system has cylindrical process zone, which allows three-dimensional objects to be irradiated with one-pass treatment. The second is a tube-type small EB processor, achieving not only its compactor design, but also higher beam extraction efficiency and flexible installation of the irradiation heads. The basic design of each processor and potential applications with them will be presented in this paper. (author)

76 FR 40303 - Revisions to the California State Implementation Plan, South Coast Air Quality Management District

Science.gov (United States)

2011-07-08

... the California State Implementation Plan, South Coast Air Quality Management District AGENCY... limited disapproval of revisions to the South Coast Air Quality Management District (SCAQMD) portion of... designated nonattainment for the fine particulate matter (PM2.5) National Ambient Air Quality Standards...

Results of revision anterior shoulder stabilization surgery in adolescent athletes.

Science.gov (United States)

Blackman, Andrew J; Krych, Aaron J; Kuzma, Scott A; Chow, Roxanne M; Camp, Christopher; Dahm, Diane L

2014-11-01

The purpose of this study was to determine failure rates, functional outcomes, and risk factors for failure after revision anterior shoulder stabilization surgery in high-risk adolescent athletes. Adolescent athletes who underwent primary anterior shoulder stabilization were reviewed. Patients undergoing subsequent revision stabilization surgery were identified and analyzed. Failure rates after revision surgery were assessed by Kaplan-Meier analysis. Failure was defined as recurrent instability requiring reoperation. Functional outcomes included the Marx activity score; American Shoulder and Elbow Surgeons score; and University of California, Los Angeles score. The characteristics of patients who required reoperation for recurrent instability after revision surgery were compared with those of patients who required only a single revision to identify potential risk factors for failure. Of 90 patients who underwent primary anterior stabilization surgery, 15 (17%) had failure and underwent revision surgery (mean age, 16.6 years; age range, 14 to 18 years). The mean follow-up period was 5.5 years (range, 2 to 12 years). Of the 15 revision patients, 5 (33%) had recurrent dislocations and required repeat revision stabilization surgery at a mean of 50 months (range, 22 to 102 months) after initial revision. No risk factors for failure were identified. The Kaplan-Meier reoperation-free estimates were 86% (95% confidence interval, 67% to 100%) at 24 months and 78% (95% confidence interval, 56% to 100%) at 48 months after revision surgery. The mean final Marx activity score was 14.8 (range, 5 to 20); American Shoulder and Elbow Surgeons score, 82.1 (range, 33 to 100); and University of California, Los Angeles score, 30.8 (range, 16 to 35). At 5.5 years' follow-up, adolescent athletes had a high failure rate of revision stabilization surgery and modest functional outcomes. We were unable to convincingly identify specific risk factors for failure of revision surgery. Level IV

Plan-Belief Revision in Jason

DEFF Research Database (Denmark)

Jensen, Andreas Schmidt; Villadsen, Jørgen

2015-01-01

When information is shared between agents of unknown reliability, it is possible that their belief bases become inconsistent. In such cases, the belief base must be revised to restore consistency, so that the agent is able to reason. In some cases the inconsistent information may be due to use of...... of incorrect plans. We extend work by Alechina et al. to revise belief bases in which plans can be dynamically added and removed. We present an implementation of the algorithm in the AgentSpeak implementation Jason....

Revised Huang-Yang multipolar pseudopotential

International Nuclear Information System (INIS)

Derevianko, Andrei

2005-01-01

A number of authors have recently pointed out inconsistencies of results obtained with the Huang-Yang multipolar pseudopotential for low-energy scattering [K. Huang and K. C. Yang, Phys. Rev. 105, 767 (1957); later revised by Huang, Statistical Mechanics (Wiley, New York, 1963)]. The conceptual validity of their original derivation has been questioned. Here I show that these inconsistencies are rather due to an algebraic mistake made by Huang and Yang. With the corrected error, I present the revised version of the multipolar pseudopotential

Design, performance, and calibration of the CMS hadron-outer calorimeter

International Nuclear Information System (INIS)

Abdullin, S.; Gavrilov, V.; Ilyina, N.; Kaftanov, V.; Kisselevich, I.; Kolossov, V.; Krokhotin, A.; Kuleshov, S.; Pozdnyakov, A.; Safronov, G.; Semenov, S.; Stolin, V.; Ulyanov, A.; Abramov, V.; Goncharov, P.; Kalinin, A.; Khmelnikov, A.; Korablev, A.; Korneev, Y.; Krinitsyn, A.; Kryshkin, V.; Lukanin, V.; Pikalov, V.; Ryazanov, A.; Talov, V.; Turchanovich, L.; Volkov, A.; Acharya, B.; Aziz, T.; Banerjee, Sudeshna; Banerjee, Sunanda; Bose, S.; Chendvankar, S.; Deshpande, P.V.; Dugad, S.; Ganguli, S.N.; Guchait, M.; Gurtu, A.; Kalmani, S.; Krishnaswamy, M.R.; Maity, M.; Majumder, G.; Mazumdar, K.; Mondal, N.; Nagaraj, P.; Narasimham, V.S.; Patil, M.; Reddy, L.; Satyanarayana, B.; Sharma, S.; Sudhakar, K.; Tonwar, S.; Verma, P.; Adam, N.; Fisher, W.; Halyo, V.; Hunt, A.; Jones, J.; Laird, E.; Landsberg, G.; Marlow, D.; Tully, C.; Werner, J.; Adams, M.; Bard, R.; Burchesky, K.; Qian, W.; Akchurin, N.; Berntzon, L.; Carrell, K.; Guemues, K.; Jeong, C.; Kim, H.; Lee, S.W.; Popescu, S.; Roh, Y.; Spezziga, M.; Thomas, R.; Volobouev, I.; Wigmans, R.; Yazgan, E.; Akgun, U.; Albayrak, E.; Ayan, S.; Clarida, W.; Debbins, P.; Duru, F.; Ingram, D.; Merlo, J.P.; Mestvirishvili, A.; Miller, M.; Moeller, A.; Norbeck, E.; Olson, J.; Onel, Y.; Ozok, F.; Schmidt, I.; Yetkin, T.; Anderson, E.W.; Hauptman, J.; Antchev, G.; Arcidy, M.; Hazen, E.; Heister, A.; Lawlor, C.; Lazic, D.; Machado, E.; Posch, C.; Rohlf, J.; Sulak, L.; Varela, F.; Wu, S.X.; Aydin, S.; Bakirci, M.N.; Cerci, S.; Dumanoglu, I.; Erturk, S.; Eskut, E.; Kayis-Topaksu, A.; Onengut, G.; Ozkurt, H.; Polatoz, A.; Sogut, K.; Topakli, H.; Vergili, M.; Baarmand, M.; Mermerkaya, H.; Ralich, R.M.; Vodopiyanov, I.; Babich, K.; Golutvin, I.; Kalagin, V.; Kosarev, I.; Ladygin, V.; Mescheryakov, G.; Moissenz, P.; Petrosyan, A.; Rogalev, E.; Smirnov, V.; Vishnevskiy, A.; Volodko, A.; Zarubin, A.; Baden, D.; Eno, S.; Grassi, T.; Jarvis, C.; Kellogg, R.; Kunori, S.; Skuja, A.; Wang, L.; Wetstein, M.; Barnes, V.; Laasanen, A.; Pompos, A.; Bawa, H.; Beri, S.; Bhandari, V.; Bhatnagar, V.; Kaur, M.; Kohli, J.; Kumar, A.; Singh, B.; Singh, J.B.; Baiatian, G.; Sirunyan, A.; Bencze, G.; Laszlo, A.; Pal, A.; Vesztergombi, G.; Zalan, P.; Bhatti, A.; Bodek, A.; Budd, H.; Chung, Y.; Barbaro, P. de; Haelen, T.; Bose, T.; Esen, S.; Vanini, A.; Camporesi, T.; Visser, T. de; Efthymiopoulos, I.; Cankocak, K.; Cremaldi, L.; Reidy, J.; Sanders, D.A.; Cushman, P.; Ma, Y.; Sherwood, B.; Damgov, J.; Piperov, S.; Deliomeroglu, M.; Guelmez, E.; Isiksal, E.; Kaya, M.; Kaya, O.; Ozkorucuklu, S.; Sonmez, N.; Demianov, A.; Ershov, A.; Gribushin, A.; Kodolova, O.; Petrushanko, S.; Sarycheva, L.; Teplov, K.; Vardanyan, I.; Diaz, J.; Gaultney, V.; Kramer, L.; Linn, S.; Lobolo, L.; Markowitz, P.; Martinez, G.; Dimitrov, L.; Genchev, V.; Vankov, I.; Elias, J.; Elvira, D.; Freeman, J.; Green, D.; Los, S.; Ronzhin, A.; Sergeyev, S.; Suzuki, I.; Vidal, R.; Whitmore, J.; Emeliantchik, I.; Mossolov, V.; Shumeiko, N.; Stefanovich, R.; Fenyvesi, A.; Gamsizkan, H.; Murat Gueler, A.; Ozkan, C.; Sekmen, S.; Serin, M.; Sever, R.; Zeyrek, M.; Gleyzer, S.; Hagopian, S.; Hagopian, V.; Johnson, K.; Grinev, B.; Lubinsky, V.; Senchishin, V.; Hashemi, M.; Mohammadi-Najafabadi, M.; Paktinat, S.; Heering, A.; Karmgard, D.; Ruchti, R.; Levchuk, L.; Sorokin, P.; Litvintsev, D.; Mans, J.; Penzo, A.; Podrasky, V.; Sanzeni, C.; Winn, D.; Vlassov, E.

2008-01-01

The Outer Hadron Calorimeter (HCAL HO) of the CMS detector is designed to measure the energy that is not contained by the barrel (HCAL HB) and electromagnetic (ECAL EB) calorimeters. Due to space limitation the barrel calorimeters do not contain completely the hadronic shower and an outer calorimeter (HO) was designed, constructed and inserted in the muon system of CMS to measure the energy leakage. Testing and calibration of the HO was carried out in a 300 GeV/c test beam that improved the linearity and resolution. HO will provide a net improvement in missing E T measurements at LHC energies. Information from HO will also be used for the muon trigger in CMS. (orig.)

Design, performance, and calibration of the CMS hadron-outer calorimeter

Energy Technology Data Exchange (ETDEWEB)

Abdullin, S.; Gavrilov, V.; Ilyina, N.; Kaftanov, V.; Kisselevich, I.; Kolossov, V.; Krokhotin, A.; Kuleshov, S.; Pozdnyakov, A.; Safronov, G.; Semenov, S.; Stolin, V.; Ulyanov, A. [ITEP, Moscow (Russian Federation); Abramov, V.; Goncharov, P.; Kalinin, A.; Khmelnikov, A.; Korablev, A.; Korneev, Y.; Krinitsyn, A.; Kryshkin, V.; Lukanin, V.; Pikalov, V.; Ryazanov, A.; Talov, V.; Turchanovich, L.; Volkov, A. [IHEP, Protvino (Russian Federation); Acharya, B.; Aziz, T.; Banerjee, Sudeshna; Banerjee, Sunanda; Bose, S.; Chendvankar, S.; Deshpande, P.V.; Dugad, S.; Ganguli, S.N.; Guchait, M.; Gurtu, A.; Kalmani, S.; Krishnaswamy, M.R.; Maity, M.; Majumder, G.; Mazumdar, K.; Mondal, N.; Nagaraj, P.; Narasimham, V.S.; Patil, M.; Reddy, L.; Satyanarayana, B.; Sharma, S.; Sudhakar, K.; Tonwar, S.; Verma, P. [Tata Inst. of Fundamental Research, Mumbai (India); Adam, N.; Fisher, W.; Halyo, V.; Hunt, A.; Jones, J.; Laird, E.; Landsberg, G.; Marlow, D.; Tully, C.; Werner, J. [Princeton Univ., NJ (United States); Adams, M.; Bard, R.; Burchesky, K.; Qian, W. [Univ. of Illinois, Chicago, IL (United States); Akchurin, N.; Berntzon, L.; Carrell, K.; Guemues, K.; Jeong, C.; Kim, H.; Lee, S.W.; Popescu, S.; Roh, Y.; Spezziga, M.; Thomas, R.; Volobouev, I.; Wigmans, R.; Yazgan, E. [Texas Tech Univ., Lubbock, TX (United States); Akgun, U.; Albayrak, E.; Ayan, S.; Clarida, W.; Debbins, P.; Duru, F.; Ingram, D.; Merlo, J.P.; Mestvirishvili, A.; Miller, M.; Moeller, A.; Norbeck, E.; Olson, J.; Onel, Y.; Ozok, F.; Schmidt, I.; Yetkin, T. [Univ. of Iowa, Iowa City, IA (United States); Anderson, E.W.; Hauptman, J. [Iowa State Univ., Ames, IA (United States); Antchev, G.; Arcidy, M.; Hazen, E.; Heister, A.; Lawlor, C.; Lazic, D.; Machado, E.; Posch, C.; Rohlf, J.; Sulak, L.; Varela, F.; Wu, S.X. [Boston Univ., MA (United States); Aydin, S.; Bakirci, M.N.; Cerci, S.; Dumanoglu, I.; Erturk, S.; Eskut, E.; Kayis-Topaksu, A.; Onengut, G.; Ozkurt, H.; Polatoz, A.; Sogut, K. [and others

2008-10-15

The Outer Hadron Calorimeter (HCAL HO) of the CMS detector is designed to measure the energy that is not contained by the barrel (HCAL HB) and electromagnetic (ECAL EB) calorimeters. Due to space limitation the barrel calorimeters do not contain completely the hadronic shower and an outer calorimeter (HO) was designed, constructed and inserted in the muon system of CMS to measure the energy leakage. Testing and calibration of the HO was carried out in a 300 GeV/c test beam that improved the linearity and resolution. HO will provide a net improvement in missing E{sub T} measurements at LHC energies. Information from HO will also be used for the muon trigger in CMS. (orig.)

Revision surgery due to magnet dislocation in cochlear implant patients: an emerging complication.

Science.gov (United States)

Hassepass, Frederike; Stabenau, Vanessa; Maier, Wolfgang; Arndt, Susan; Laszig, Roland; Beck, Rainer; Aschendorff, Antje

2014-01-01

To analyze the cause and effect of magnet dislocation in cochlear implant (CI) recipients requiring magnet revision surgery for treatment. Retrospective study. Tertiary referral center. Case reports from 1,706 CI recipients consecutively implanted from January 2000 to December 2011 were reviewed. The number of cases requiring magnet revision surgery was assessed. Revision surgery involving magnet removal or replacement was indicated in 1.23% (21/1,706), of all CI recipients. Magnet dislocation occurring during magnetic resonance tomography (MRI), at 1.5 Tesla (T), with the magnet in place and with the application of compression bandaging around the head, was the main cause for revision surgery in 47.62% (10/21) of the affected cases. All 10 cases were implanted with Cochlear Nucleus cochlear implants. These events occurred, despite adherence to current recommendations of the manufacturer. The present study underlines that MRI examination is the main cause of magnet dislocation. The use of compressive bandaging when using 1.5-T MRI does not eliminate the risk of magnet dislocation. Additional cautionary measures are for required for conditional MRI. We recommend X-ray examination after MRI to determine magnet dislocation and avoid major complications in all cases reporting pain during or after MRI. Additional research regarding silicon magnet pocket design for added retention is needed. Effective communication of guidelines for precautionary measures during MRI examination in CI patients is mandatory for all clinicians involved. MRI in CI recipients should be indicated with caution.

Trends in Revision Elbow Ulnar Collateral Ligament Reconstruction in Professional Baseball Pitchers.

Science.gov (United States)

Wilson, Alexander T; Pidgeon, Tyler S; Morrell, Nathan T; DaSilva, Manuel F

2015-11-01

To determine the frequency of revision elbow ulnar collateral ligament (UCL) reconstruction in professional baseball pitchers. Data were collected on 271 professional baseball pitchers who underwent primary UCL reconstruction. Each player was evaluated retrospectively for occurrence of revision UCL reconstructive surgery to treat failed primary reconstruction. Data on players who underwent revision UCL reconstruction were compiled to determine total surgical revision incidence and revision rate by year. The incidence of early revision was analyzed for trends. Average career length after primary UCL reconstruction was calculated and compared with that of players who underwent revision surgery. Logistic regression analysis was performed to assess risk factors for revision including handedness, pitching role, and age at the time of primary reconstruction. Between 1974 and 2014, the annual incidence of primary UCL reconstructions among professional pitchers increased, while the proportion of cases being revised per year decreased. Of the 271 pitchers included in the study, 40 (15%) required at least 1 revision procedure during their playing career. Three cases required a second UCL revision reconstruction. The average time from primary surgery to revision was 5.2 ± 3.2 years (range, 1-13 years). The average length of career following primary reconstruction for all players was 4.9 ± 4.3 years (range, 0-22 years). The average length of career following revision UCL reconstruction was 2.5 ± 2.4 years (range, 0-8 years). No risk factors for needing revision UCL reconstruction were identified. The incidence of primary UCL reconstructions among professional pitchers is increasing; however, the rate of primary reconstructions requiring revision is decreasing. Explanations for the decreased revision rate may include improved surgical technique and improved rehabilitation protocols. Therapeutic IV. Copyright © 2015 American Society for Surgery of the Hand. Published by

The nuclear liability conventions revised

International Nuclear Information System (INIS)

Reyners, P.

2004-01-01

The signature on 12 February 2004 of the Protocols amending respectively the 1960 Paris Convention and the 1963 Brussels Supplementary Convention was the second step of the process of modernisation of the international nuclear liability regime after the adoption in September 1997 of a Protocol revising the 1963 Vienna Convention and of a new Convention on Supplementary Compensation for Nuclear Damage. The common objective of the new instruments is to provide more funds to compensate a larger number of potential victims in respect of a broader range of damage. Another goal of the revision exercise was to maintain the compatibility between the Paris and Vienna based systems, a commitment enshrined in the 1988 Joint Protocol, as well as to ascertain that Paris/Brussels countries could also become a Party to the Convention on Supplementary Compensation. However, while generally consistent vis a vis the Joint Protocol, the provisions of the Paris and Vienna Conventions, as revised, differ on some significant aspects. Another remaining issue is whether the improved international nuclear liability regime will succeed in attracting in the future a larger number of countries, particularly outside Europe, and will so become truly universal. Therefore, the need for international co-operation to address these issues, to facilitate the adoption of new implementing legislation and to ensure that this special regime keeps abreast of economic and technological developments, is in no way diminished after the revision of the Conventions.(author)

Revising an Engineering Design Rubric: A Case Study Illustrating Principles and Practices to Ensure Technical Quality of Rubrics

Science.gov (United States)

Goldberg, Gail Lynn

2014-01-01

This article provides a detailed account of a rubric revision process to address seven common problems to which rubrics are prone: lack of consistency and parallelism; the presence of "orphan" and "widow" words and phrases; redundancy in descriptors; inconsistency in the focus of qualifiers; limited routes to partial credit;…

Recent developments in the IAEA safety standards: design and operation of nuclear power plants

International Nuclear Information System (INIS)

Saito, Takehiko

2004-01-01

The IAEA has been publishing a wide variety of safety standards for nuclear and radiation related facilities and activities since 1978. In 1996, a more rigorously structured approach for the preparation and review of its safety standards was introduced. Currently, based on the approach, revision of most of the standards is in completion or near completion. The latest versions of the Safety Requirements for ''Design'' and ''Operation'' of nuclear power plants were respectively published in 2000. Currently, along with this revision of the Safety Requirements, many Safety Guides have been revised. In order to clarify the complicated revision procedure, an example of the entire revision process for a Safety Guide is provided. Through actual example of the revision process, enormous amount of work involved in the revision work is clearly indicated. The current status of all of the Safety Standards for Design and that for Operation of nuclear power plants are summarized. Summary of other IAEA safety standards currently revised and available related IAEA publications, together with information on the IAEA Web Site from where these documents can be downloaded, is also provided. The standards are reviewed to determine whether revision (or new issue) is necessary in five years following publication. The IAEA safety standards will continue to be updated through comprehensive and structured approach, collaboration of many experts of the world, and reflecting good practices of the world. The IAEA safety standards will serve to provide high level of safety assurance. (author)

Clinical and Radiological Results over the Medium Term of Isolated Acetabular Revision

Directory of Open Access Journals (Sweden)

Nicola Piolanti

2014-01-01

Full Text Available Acetabular cup loosening is associated with pain, reduced function, and instability of the implant. If such event happens while the femoral implant is in a satisfactory position and is well fixed to the bone, isolated acetabular revision surgery is indicated. The aim of this single-center retrospective study was to evaluate the clinical and radiological results over the medium term (12-month follow-up mean 36, max 60 of isolated acetabular revisions surgery using a porous hemispheric revision shell matched with a cemented all-poly cup and large diameter femoral head (>32. 33 patients were enrolled. We collect any relevant data from the clinical board. Routine clinical and radiographic examinations were performed preoperatively; the postoperative follow-up was made at 1, 3, and 6 months and yearly thereafter. At the last available follow-up, we report satisfactory improvement of functional scores in all the patients; 2 patients (6.1% showed thigh pain and only 4 hips (12.11% presented mild groin pain; all the femoral components are well fixed and there were no potential or pending rerevisions. With bias due to the follow-up and to the retrospective design of the study, we report clinical, functional, and radiological satisfactory results.

Sequenced Peer Revision: Creating Competence and Community

Science.gov (United States)

Bowman, Ingrid K.; Robertson, John

2013-01-01

Mastering techniques of self- and peer revision is a valuable tool for all writers, especially US-educated Generation 1.5 students, whose near fluency enables them to dialogue successfully about their writing. Using action research, 2 academic writing instructors systematically trained students to more responsibly and effectively revise their…

Quantum interaction. Revised selected papers

International Nuclear Information System (INIS)

Song, Dawei; Zhang, Peng; Wang, Lei; Arafat, Sachi

2011-01-01

This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Symposium on Quantum Interaction, QI 2011, held in Aberdeen, UK, in June 2011. The 26 revised full papers and 6 revised poster papers, presented together with 1 tutorial and 1 invited talk were carefully reviewed and selected from numerous submissions during two rounds of reviewing and improvement. The papers show the cross-disciplinary nature of quantum interaction covering topics such as computation, cognition, mechanics, social interaction, semantic space and information representation and retrieval. (orig.)

Quantum interaction. Revised selected papers

Energy Technology Data Exchange (ETDEWEB)

Song, Dawei; Zhang, Peng; Wang, Lei [Aberdeen Univ. (United Kingdom). School of Computing; Melucci, Massimo [Padua Univ., Padova (Italy). Dept. of Information Engineering; Frommholz, Ingo [Bedfordshire Univ. (United Kingdom); Arafat, Sachi (eds.) [Glasgow Univ. (United Kingdom). School of Computing Science

2011-07-01

This book constitutes the thoroughly refereed post-conference proceedings of the 5th International Symposium on Quantum Interaction, QI 2011, held in Aberdeen, UK, in June 2011. The 26 revised full papers and 6 revised poster papers, presented together with 1 tutorial and 1 invited talk were carefully reviewed and selected from numerous submissions during two rounds of reviewing and improvement. The papers show the cross-disciplinary nature of quantum interaction covering topics such as computation, cognition, mechanics, social interaction, semantic space and information representation and retrieval. (orig.)

Medical writing, revising and editing

DEFF Research Database (Denmark)

Pilegaard, Morten

2006-01-01

The globalization of science makes medical writing, editing and revision a rapidly growing field of linguistic study and practice. Medical science texts are written according to uniform, general guidelines and medical genres have become highly conventionalized in terms of structure and linguistic...... form. Medical editing often takes the form of peer review and mainly addresses issues of contents and overall validity. Medical revision incorporates the checking of the macrostructure and the microstructure of the text, its language and style and its suitability for the target reader or client...

Cold in-place recycle phase III, mix design.

Science.gov (United States)

2014-10-01

This projects purpose is to revise the UDOT accepted design methods for Cold In-Place Recycling so that they : better reflect field behavior and target the desirable attributes of the material. The previous design process failed to : adequately pr...

Physical and Chemical Environmental Abstraction Model

International Nuclear Information System (INIS)

Nowak, E.

2000-01-01

As directed by a written development plan (CRWMS M and O 1999a), Task 1, an overall conceptualization of the physical and chemical environment (P/CE) in the emplacement drift is documented in this Analysis/Model Report (AMR). Included are the physical components of the engineered barrier system (EBS). The intended use of this descriptive conceptualization is to assist the Performance Assessment Department (PAD) in modeling the physical and chemical environment within a repository drift. It is also intended to assist PAD in providing a more integrated and complete in-drift geochemical model abstraction and to answer the key technical issues raised in the U.S. Nuclear Regulatory Commission (NRC) Issue Resolution Status Report (IRSR) for the Evolution of the Near-Field Environment (NFE) Revision 2 (NRC 1999). EBS-related features, events, and processes (FEPs) have been assembled and discussed in ''EBS FEPs/Degradation Modes Abstraction'' (CRWMS M and O 2000a). Reference AMRs listed in Section 6 address FEPs that have not been screened out. This conceptualization does not directly address those FEPs. Additional tasks described in the written development plan are recommended for future work in Section 7.3. To achieve the stated purpose, the scope of this document includes: (1) the role of in-drift physical and chemical environments in the Total System Performance Assessment (TSPA) (Section 6.1); (2) the configuration of engineered components (features) and critical locations in drifts (Sections 6.2.1 and 6.3, portions taken from EBS Radionuclide Transport Abstraction (CRWMS M and O 2000b)); (3) overview and critical locations of processes that can affect P/CE (Section 6.3); (4) couplings and relationships among features and processes in the drifts (Section 6.4); and (5) identities and uses of parameters transmitted to TSPA by some of the reference AMRs (Section 6.5). This AMR originally considered a design with backfill, and is now being updated (REV 00 ICN1) to address

The design of the acetabular component and size of the femoral head influence the risk of revision following 34 721 single-brand cemented hip replacements: a retrospective cohort study of medium-term data from a National Joint Registry.

Science.gov (United States)

Jameson, S S; Baker, P N; Mason, J; Gregg, P J; Brewster, N; Deehan, D J; Reed, M R

2012-12-01

Despite excellent results, the use of cemented total hip replacement (THR) is declining. This retrospective cohort study records survival time to revision following primary cemented THR using the most common combination of components that accounted for almost a quarter of all cemented THRs, exploring risk factors independently associated with failure. All patients with osteoarthritis who had an Exeter V40/Contemporary THR (Stryker) implanted before 31 December 2010 and recorded in the National Joint Registry for England and Wales were included in the analysis. Cox's proportional hazard models were used to analyse the extent to which risk of revision was related to patient, surgeon and implant covariates, with a significance threshold of p brand of cement/presence of antibiotic, femoral head material (stainless steel/alumina) and stem taper size/offset. However, the risk of revision for dislocation was significantly higher with a 'plus' offset head (HR 2.05, p = 0.003) and a hooded acetabular component (HR 2.34, p designs of acetabular component and sizes of femoral head after adjustment for a range of covariates.

Human Work Interaction Design

DEFF Research Database (Denmark)

Lopes, Arminda; Ørngreen, Rikke

This book constitutes the thoroughly refereed post-conference proceedings of the Third IFIP WG 13.6 Working Conference on Human Work Interaction Design, HWID 2012, held in Copenhagen, Denmark, in December 2012. The 16 revised papers presented were carefully selected for inclusion in this volume...

Revision of the Neotropical genus Protoconnus Franz (Coleoptera: Staphylinidae: Scydmaeninae).

Science.gov (United States)

JaŁoszyŃski, PaweŁ

2018-03-07

The Neotropical genus Protoconnus Franz, belonging to the tribe Glandulariini, is revised. Protoconnus is redefined based on detailed morphological study, and all known species are revised, including 10 originally placed in Protoconnus, one transferred from Euconnus, and 14 described as new. The following species are treated: P. andicola Franz (Peru), P. peruensis Franz (Peru), P. minutus Franz (Peru), P. minutissimus Franz (Peru), P. venezolanus Franz (Venezuela), P. araguanus Franz (Venezuela), P. bolivianus Franz (Bolivia), P. comarapae Franz (Bolivia), P. robustus Franz (Bolivia), P. paraguayanus Franz (Paraguay), P. princeps (Franz), comb. n. (ex Euconnus) (Peru), P. quillabambanus sp. n. (Peru), P. ecuadoranus sp. n. (Ecuador), P. napoanus sp. n. (Ecuador), P. magnus sp. n. (Ecuador), P. impressifrons sp. n. (Bolivia), P. angustus sp. n. (Bolivia), P. acutus sp. n. (Bolivia), P. tunarianus sp. n. (Bolivia), P. apaapa sp. n. (Bolivia), P. maximus sp. n. (Costa Rica), P. minusculus sp. n. (Costa Rica), P. costaricanus sp. n. (Costa Rica), P. inexpectatus sp. n. (Costa Rica), and P. volcanbaru sp. n. (Panama). Lectotypes are designated for P. andicola and P. peruensis.

The New Design Handbook for School Food Service. Revised.

Science.gov (United States)

Silberberg, Susan Crowl

A handbook, created for both designers and users of food service facilities in schools, provides reference information and guidance for making sure schools can provide quality food service. The handbook's first six chapters include explanations on how to start a school food service design project; required space, including kitchen work flow and…

Microbiological diagnosis in revision of infected knee arthroplasties in Denmark

DEFF Research Database (Denmark)

Lindberg-Larsen, Martin; Pitter, Frederik Taylor; Voldstedlund, Marianne

2017-01-01

. METHODS: One hundred and two partial revisions (open debridement and exchange of tibial insert) and 213 two-stage procedures performed due to infection in 275 patients from 1 July 2011 to 30 June 2013 were included and analysed by linkage to data from a nationwide registry on microbiological test results....... RESULTS: 78 (24.8%) revisions were culture negative, 192 (60.9%) showed monomicrobial growth and 43 (14.3%) polymicrobial growth. Staphylococcus aureus was the most frequent isolate in mono-culture in 70 (22.2%) revisions and in polymicrobial culture in 15 revisions with a total frequency of 27.0%. Only...... one case (1.4%) of methicillin-resistance was registered. Coagulase-negative staphylococci (CoNS) were frequent, sole pathogen in 65 revisions and in polymicrobial cultures in 28 revisions with a total frequency of 29.5%. A pre-operative knee aspiration was performed in 50% and preoperative blood...

Developing an Engineering Design Process Assessment using Mixed Methods.

Science.gov (United States)

Wind, Stefanie A; Alemdar, Meltem; Lingle, Jeremy A; Gale, Jessica D; Moore, Roxanne A

Recent reforms in science education worldwide include an emphasis on engineering design as a key component of student proficiency in the Science, Technology, Engineering, and Mathematics disciplines. However, relatively little attention has been directed to the development of psychometrically sound assessments for engineering. This study demonstrates the use of mixed methods to guide the development and revision of K-12 Engineering Design Process (EDP) assessment items. Using results from a middle-school EDP assessment, this study illustrates the combination of quantitative and qualitative techniques to inform item development and revisions. Overall conclusions suggest that the combination of quantitative and qualitative evidence provides an in-depth picture of item quality that can be used to inform the revision and development of EDP assessment items. Researchers and practitioners can use the methods illustrated here to gather validity evidence to support the interpretation and use of new and existing assessments.

Identification of the IGF-1 processing product human Ec/rodent Eb peptide in various tissues: Evidence for its differential regulation after exercise-induced muscle damage in humans.

Science.gov (United States)

Vassilakos, George; Philippou, Anastassios; Koutsilieris, Michael

2017-02-01

Insulin-like growth factor-1 (IGF-1) is a pleiotropic factor expressed in various tissues and plays a critical role in skeletal muscle physiology. Alternative splicing of the IGF-1 gene gives rise to different precursor polypeptides (isoforms) which could undergo post-translational cleavage, generating the common mature IGF-1 peptide and different carboxyl terminal extension (E-) peptides, with the fate of the latter being, so far, unknown. The objective if this study was to identify the IGF-1Ec forms or processing product(s), other than mature IGF-1, generated in different human and rodent tissues and particularly in human skeletal muscle after exercise-induced damage. Protein lysates from a wide range of human and rodent tissues were immunoblotted with a rabbit anti-human Ec polyclonal antibody raised against the last 24 amino acids of the C-terminal of the Ec peptide. This antibody can recognize the Ec peptide, both as part of IGF-1Ec and alone, and also the corresponding rodent forms, due to the high homology that the human Ec shares with the rodent Eb. We were able to confirm, for the first time, that the human Ec peptide and its rodent homologous Eb peptide are produced simultaneously with their precursor protein (pro-IGF-1Ec/Eb) in vivo, in a wide range of tissues (e.g. muscle, liver, heart). Proprotein convertase furin digestion of human muscle and liver protein lysates confirmed that the higher molecular form, pro-IGF-1Ec, can be cleaved to produce the free Ec peptide. Furthermore, initial evidence is provided that Ec peptide is differentially regulated during the process of muscle regeneration after exercise-induced damage in humans. The findings of this study possibly imply that the post-translational modification of the IGF-1Ec pro-peptide may regulate the bioavailability and activity of the processing product(s). Copyright © 2016. Published by Elsevier Ltd.

Pain and Function Following Revision Cubital Tunnel Surgery.

Science.gov (United States)

Davidge, Kristen M; Ebersole, Gregory C; Mackinnon, Susan E

2017-11-01

The purpose of this study was to determine pain and functional outcomes following revision cubital tunnel surgery and to identify predictors of poor postoperative outcome. A retrospective cohort study was conducted of all patients undergoing revision cubital tunnel surgery over a 5-year period at a high-volume peripheral nerve center. Intraoperative findings, demographic and injury factors, and outcomes were reviewed. Average pain, worst pain, and impact of pain on self-perceived quality of life were each measured using a 10-cm visual analog scale (VAS). Function was evaluated using pinch and grip strength, as well as the Disabilities of the Arm, Shoulder and Hand (DASH) questionnaire. Differences in preoperative and postoperative pain, strength, and DASH were analyzed using nonparametric tests. Predictors of postoperative average pain were evaluated using odds ratios and linear regression analyses. The final cohort consisted of 50 patients (mean age: 46.3 ± 12.5 years; 29 [68%] male) undergoing 52 revision ulnar nerve transpositions (UNTs). Pain VAS scores decreased significantly following revision UNT. Strength and DASH scores demonstrated nonsignificant improvements postoperatively. Worse preoperative pain and greater than 1 prior cubital tunnel procedure were significant predictors of worse postoperative average pain VAS scores. Patients can and do improve following revision cubital tunnel surgery, particularly as it relates to pain. Intraoperative findings during the revision procedure suggest that adherence to specific principles in the primary operation is key to prevention of secondary cubital tunnel syndrome.

Fabrication drawings of fuel pins for FUJI project among PSI, JNC and NRG. Revised version 2

International Nuclear Information System (INIS)

Ozawa, Takayuki; Nakazawa, Hiroaki; Abe, Tomoyuki; Nagayama, Masahiro

2002-10-01

Irradiation tests and post-irradiation examinations in the framework of JNC-PSI-NRG collaboration project will be performed in 2003-2005. Irradiation fuel pins will be fabricated by the middle of 2003. The fabrication procedure for irradiation fuel pins has been started in 2001. Several fabrication tests and qualification tests in JNC and PSI (Paul Scherrer Institut, Switzerland) have been performed before the fuel pin fabrication. According to the design assignment between PSI and JNC in the frame of this project, PSI should make specification documents for the fuel pellet, the sphere-pac fuel particles, the vipac fuel fragments, and the fuel segment fabrication. JNC should make the fabrication drawings for irradiation pins. JNC has been performed the fuel design in cooperation with PSI and NRG (Nuclear Research and Consultancy Group, Holland). In this project, the pelletized fuel, the sphere-pac fuel, and the vipac fuel will be simultaneously irradiated on HFR (High Flux Reactor, Holland). The fabrication drawings have been made under the design assignment with PSI, and consist of the drawings of MOX pellet, thermal insulator pellet, pin components, fuel segments, and the constructed pin. The fabrication drawings were approved in October 2001, but after that, the optimization of specifications was discussed and agreed among all partners. According to this agreement, the fabrication drawings were revised in January 2002. After the earlier revision, the shape of particle retainer to be made by PSI was modified from its drawing beforehand delivered. In this report, the fabrication drawings revised again will be shown, and the fabrication procedure (welding Qualification Tests) will be modified in accordance with the result of discussion on the 3rd technical meeting held in September 2002. These design works have been performed in Fuel Design and Evaluation Group, Plutonium Fuel Fabrication Division, Plutonium Fuel Center under the commission of Plutonium Fuel

Revision hip preservation surgery with hip arthroscopy: clinical outcomes.

Science.gov (United States)

Domb, Benjamin G; Stake, Christine E; Lindner, Dror; El-Bitar, Youseff; Jackson, Timothy J

2014-05-01

To analyze and report the clinical outcomes of a cohort of patients who underwent revision hip preservation with arthroscopy and determine predictors of positive and negative outcomes. During the study period from April 2008 to December 2010, all patients who underwent revision hip preservation with arthroscopy were included. This included patients who had previous open surgery and underwent revision with arthroscopy. Patient-reported outcome (PRO) scores were obtained preoperatively and at 3-month, 1-year, 2-year, and 3-year follow-up time points. Any revision surgeries and conversions to total hip arthroplasty were noted. A multiple regression analysis was performed to look for positive and negative predictive factors for improvement in PROs after revision hip arthroscopy. Forty-seven hips in 43 patients had completed 2 years' follow-up or needed total hip arthroplasty. The mean length of follow-up was 29 months (range, 24 to 47 months). Of the hips, 31 (66%) had either unaddressed or incompletely treated femoroacetabular impingement. There was a significant improvement in all PRO scores at a mean of 29 months after revision (P arthroscopy can achieve moderately successful outcomes and remains a viable treatment strategy after failed primary hip preservation surgery. Preoperative predictors of success after revision hip arthroscopy include segmental labral defects, unaddressed or incompletely addressed femoroacetabular impingement, heterotopic ossification, and previous open surgery. Level IV, therapeutic case series. Copyright © 2014 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

HEDR modeling approach: Revision 1

International Nuclear Information System (INIS)

Shipler, D.B.; Napier, B.A.

1994-05-01

This report is a revision of the previous Hanford Environmental Dose Reconstruction (HEDR) Project modeling approach report. This revised report describes the methods used in performing scoping studies and estimating final radiation doses to real and representative individuals who lived in the vicinity of the Hanford Site. The scoping studies and dose estimates pertain to various environmental pathways during various periods of time. The original report discussed the concepts under consideration in 1991. The methods for estimating dose have been refined as understanding of existing data, the scope of pathways, and the magnitudes of dose estimates were evaluated through scoping studies

Steel designers' handbook

CERN Document Server

Gorenc, Branko; Tinyou, Ron

2012-01-01

The Revised 7th Edition of Steel Designers' Handbook is an invaluable tool for all practising structural, civil and mechanical engineers as well as engineering students at university and TAFE in Australia and New Zealand. It has been prepared in response to changes in the design Standard AS 4100, the structural Design Actions Standards, AS /ANZ 1170, other processing Standards such as welding and coatings, updated research as well as feedback from users. This edition is based on Australian Standard (AS) 4100: 1998 and subsequent amendments. The worked numerical examples in the book have been e

Formal methods in the design of Ada 1995

Science.gov (United States)

Guaspari, David

1995-01-01

Formal, mathematical methods are most useful when applied early in the design and implementation of a software system--that, at least, is the familiar refrain. I will report on a modest effort to apply formal methods at the earliest possible stage, namely, in the design of the Ada 95 programming language itself. This talk is an 'experience report' that provides brief case studies illustrating the kinds of problems we worked on, how we approached them, and the extent (if any) to which the results proved useful. It also derives some lessons and suggestions for those undertaking future projects of this kind. Ada 95 is the first revision of the standard for the Ada programming language. The revision began in 1988, when the Ada Joint Programming Office first asked the Ada Board to recommend a plan for revising the Ada standard. The first step in the revision was to solicit criticisms of Ada 83. A set of requirements for the new language standard, based on those criticisms, was published in 1990. A small design team, the Mapping Revision Team (MRT), became exclusively responsible for revising the language standard to satisfy those requirements. The MRT, from Intermetrics, is led by S. Tucker Taft. The work of the MRT was regularly subject to independent review and criticism by a committee of distinguished Reviewers and by several advisory teams--for example, the two User/Implementor teams, each consisting of an industrial user (attempting to make significant use of the new language on a realistic application) and a compiler vendor (undertaking, experimentally, to modify its current implementation in order to provide the necessary new features). One novel decision established the Language Precision Team (LPT), which investigated language proposals from a mathematical point of view. The LPT applied formal mathematical analysis to help improve the design of Ada 95 (e.g., by clarifying the language proposals) and to help promote its acceptance (e.g., by identifying a

A reliability analysis of the revised competitiveness index.

Science.gov (United States)

Harris, Paul B; Houston, John M

2010-06-01

This study examined the reliability of the Revised Competitiveness Index by investigating the test-retest reliability, interitem reliability, and factor structure of the measure based on a sample of 280 undergraduates (200 women, 80 men) ranging in age from 18 to 28 years (M = 20.1, SD = 2.1). The findings indicate that the Revised Competitiveness Index has high test-retest reliability, high inter-item reliability, and a stable factor structure. The results support the assertion that the Revised Competitiveness Index assesses competitiveness as a stable trait rather than a dynamic state.

Manufacturing process design for multi commodities in agriculture

Science.gov (United States)

Prasetyawan, Yudha; Santosa, Andrian Henry

2017-06-01

High-potential commodities within particular agricultural sectors should be accompanied by maximum benefit value that can be attained by both local farmers and business players. In several cases, the business players are small-medium enterprises (SMEs) which have limited resources to perform added value process of the local commodities into the potential products. The weaknesses of SMEs such as the manual production process with low productivity, limited capacity to maintain prices, and unattractive packaging due to conventional production. Agricultural commodity is commonly created into several products such as flour, chips, crackers, oil, juice, and other products. This research was initiated by collecting data by interview method particularly to obtain the perspectives of SMEs as the business players. Subsequently, the information was processed based on the Quality Function Deployment (QFD) to determine House of Quality from the first to fourth level. A proposed design as the result of QFD was produced and evaluated with Technology Assessment Model (TAM) and continued with a revised design. Finally, the revised design was analyzed with financial perspective to obtain the cost structure of investment, operational, maintenance, and workers. The machine that performs manufacturing process, as the result of revised design, was prototyped and tested to determined initial production process. The designed manufacturing process offers IDR 337,897, 651 of Net Present Value (NPV) in comparison with the existing process value of IDR 9,491,522 based on similar production input.

High temperature oxidation behavior of hafnium modified NiAl bond coat in EB-PVD thermal barrier coating system

Energy Technology Data Exchange (ETDEWEB)

Guo Hongbo; Sun Lidong; Li Hefei [Department of Material Science and Engineering, Beijing University of Aeronautics and Astronautics, No.37 Xueyuan Road, Beijing 100083 (China); Gong Shengkai [Department of Material Science and Engineering, Beijing University of Aeronautics and Astronautics, No.37 Xueyuan Road, Beijing 100083 (China)], E-mail: gongsk@buaa.edu.cn

2008-06-30

NiAl coatings doped with 0.5 at.% and 1.5 at.% Hf were produced by co-evaporation of NiAl and Hf ingots by electron beam physical vapor deposition (EB-PVD), respectively. The addition of 0.5 at.% Hf significantly improved the cyclic oxidation resistance of the NiAl coating. The TGO layer in the 1.5 at.% Hf doped NiAl coating is straight; while that in the 0.5 at.% Hf doped coating became undulated after thermal cycling. The doped NiAl thermal barrier coatings (TBCs) revealed improved thermal cycling lifetimes at 1423 K, compared to the undoped TBC. Failure of the 0.5 at.% Hf doped TBC occurred by cracking at the interface between YSZ topcoat and bond coat, while the 1.5 at.% Hf doped TBC cracked at the interface between bond coat and substrate.

Designing with the mind in mind simple guide to understanding user interface design guidelines

CERN Document Server

Johnson, Jeff

2014-01-01

In this completely updated and revised edition of Designing with the Mind in Mind, Jeff Johnson provides you with just enough background in perceptual and cognitive psychology that user interface (UI) design guidelines make intuitive sense rather than being just a list or rules to follow. Early UI practitioners were trained in cognitive psychology, and developed UI design rules based on it. But as the field has evolved since the first edition of this book, designers enter the field from many disciplines. Practitioners today have enough experience in UI design that they have been exposed to

Descriptive epidemiology of the Multicenter ACL Revision Study (MARS) cohort.

Science.gov (United States)

Wright, Rick W; Huston, Laura J; Spindler, Kurt P; Dunn, Warren R; Haas, Amanda K; Allen, Christina R; Cooper, Daniel E; DeBerardino, Thomas M; Lantz, Brett Brick A; Mann, Barton J; Stuart, Michael J

2010-10-01

Revision anterior cruciate ligament (ACL) reconstruction has worse outcomes than primary reconstructions. Predictors for these worse outcomes are not known. The Multicenter ACL Revision Study (MARS) Group was developed to perform a multisurgeon, multicenter prospective longitudinal study to obtain sufficient subjects to allow multivariable analysis to determine predictors of clinical outcome. To describe the formation of MARS and provide descriptive analysis of patient demographics and clinical features for the initial 460 enrolled patients to date in this prospective cohort. Cross-sectional study; Level of evidence, 2. After training and institutional review board approval, surgeons began enrolling patients undergoing revision ACL reconstruction, recording patient demographics, previous ACL reconstruction methods, intra-articular injuries, and current revision techniques. Enrolled subjects completed a questionnaire consisting of validated patient-based outcome measures. As of April 1, 2009, 87 surgeons have enrolled a total of 460 patients (57% men; median age, 26 years). For 89%, the reconstruction was the first revision. Mode of failure as deemed by the revising surgeon was traumatic (32%), technical (24%), biologic (7%), combination (37%), infection (MARS Group has been able to quickly accumulate the largest revision ACL reconstruction cohort reported to date. Traumatic reinjury is deemed by surgeons to be the most common single mode of failure, but a combination of factors represents the most common mode of failure. Allograft graft choice is more common in the revision setting than autograft. Concomitant knee injury is extremely common in this population.

Guidelines for sea dumping packages of radioactive waste. Revised version.

International Nuclear Information System (INIS)

Anon.

1979-04-01

The purpose of these Guidelines is to establish general requirements and provide practical information for the design and manufacture of packages for sea dumping of radioactive waste, in accordance with the terms of the OECD Council Decision establishing a Multilateral Consultation and Surveillance Mechanism for Sea Dumping of Radioactive Waste. These Guidelines are in compliance with the IAEA Revised Definition and Recommendations of 1978, for applying the London Dumping Convention to radioactive waste, and are intended for application under the responsibility of the appropriate national authorities of countries participating in the NEA Mechanism

Letter of Map Revision

Data.gov (United States)

Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

Revision without ordinals

NARCIS (Netherlands)

Rivello, Edoardo

2013-01-01

We show that Herzberger’s and Gupta’s revision theories of truth can be recast in purely inductive terms, without any appeal neither to the transfinite ordinal numbers nor to the axiom of Choice. The result is presented in an abstract and general setting, emphasising both its validity for a wide

Smoking is associated with earlier time to revision of total knee arthroplasty.

Science.gov (United States)

Lim, Chin Tat; Goodman, Stuart B; Huddleston, James I; Harris, Alex H S; Bhowmick, Subhrojyoti; Maloney, William J; Amanatullah, Derek F

2017-10-01

Smoking is associated with early postoperative complications, increased length of hospital stay, and an increased risk of revision after total knee arthroplasty (TKA). However, the effect of smoking on time to revision TKA is unknown. A total of 619 primary TKAs referred to an academic tertiary center for revision TKA were retrospectively stratified according to the patient smoking status. Smoking status was then analyzed for associations with time to revision TKA using a Chi square test. The association was also analyzed according to the indication for revision TKA. Smokers (37/41, 90%) have an increased risk of earlier revision for any reason compared to non-smokers (274/357, 77%, p=0.031). Smokers (37/41, 90%) have an increased risk of earlier revision for any reason compared to ex-smokers (168/221, 76%, p=0.028). Subgroup analysis did not reveal a difference in indication for revision TKA (p>0.05). Smokers are at increased risk of earlier revision TKA when compared to non-smokers and ex-smokers. The risk for ex-smokers was similar to that of non-smokers. Smoking appears to have an all-or-none effect on earlier revision TKA as patients who smoked more did not have higher risk of early revision TKA. These results highlight the need for clinicians to urge patients not to begin smoking and encourage smokers to quit smoking prior to primary TKA. Copyright © 2017 Elsevier B.V. All rights reserved.

Hanford Site technical baseline database. Revision 1

International Nuclear Information System (INIS)

Porter, P.E.

1995-01-01

This report lists the Hanford specific files (Table 1) that make up the Hanford Site Technical Baseline Database. Table 2 includes the delta files that delineate the differences between this revision and revision 0 of the Hanford Site Technical Baseline Database. This information is being managed and maintained on the Hanford RDD-100 System, which uses the capabilities of RDD-100, a systems engineering software system of Ascent Logic Corporation (ALC). This revision of the Hanford Site Technical Baseline Database uses RDD-100 version 3.0.2.2 (see Table 3). Directories reflect those controlled by the Hanford RDD-100 System Administrator. Table 4 provides information regarding the platform. A cassette tape containing the Hanford Site Technical Baseline Database is available

Publishing and Revising Content

Science.gov (United States)

Editors and Webmasters can publish content without going through a workflow. Publishing times and dates can be set, and multiple pages can be published in bulk. Making an edit to published content created a revision.

Development and Psychometric Validation of the Family Outcomes Survey-Revised

Science.gov (United States)

Bailey, Donald B., Jr.; Raspa, Melissa; Olmsted, Murrey G.; Novak, Scott P.; Sam, Ann M.; Humphreys, Betsy P.; Nelson, Robin; Robinson, Nyle; Guillen, Chelsea

2011-01-01

Few psychometrically valid scales exist to assess family outcomes and the helpfulness of early intervention. This article describes the development and psychometric properties of the Family Outcomes Survey-Revised. The revision was prompted by the need to (a) create a new format that would be easier for parents to understand, (b) revise and expand…

Age and Early Revision After Primary Total Hip Arthroplasty for Osteoarthritis.

Science.gov (United States)

Meyer, Zachary; Baca, Geneva; Rames, Richard; Barrack, Robert; Clohisy, John; Nam, Denis

2017-11-01

Prior reports have noted an increased risk of early revision among younger patients undergoing total hip arthroplasty (THA) but have been confounded by the inclusion of various diagnoses. The purpose of this study was to assess the revision rate and the time to revision for patients undergoing THA for osteoarthritis based on age. Patients with a diagnosis of osteoarthritis who underwent both primary and revision THA at the same institution were identified. The time between primary and revision surgery and the indication for revision were collected. Patients were stratified into 2 groups based on age at the time of primary THA: 64 years or younger (group 1) or 65 years or older (group 2). Between 1996 and 2016, a total of 4662 patients (5543 hips) underwent primary THA for a diagnosis of osteoarthritis. Of these, 100 patients (104 hips) received a revision THA (62 in group 1 and 42 in group 2). Mean age was 52.7±8.4 years in group 1 vs 73.4±6.3 years in group 2 (Pprimary to revision surgery was 3.0±3.2 years for group 1 and 1.1±2.1 years for group 2 (P=.001). Among patients undergoing primary THA for a diagnosis of osteoarthritis, younger age is not associated with an increased rate of early failure or revision. [Orthopedics. 2017; 40(6):e1069-e1073.]. Copyright 2017, SLACK Incorporated.

Revision washout decreases implant capsule tissue culture positivity: a multicenter study.

Science.gov (United States)

Henry, Gerard D; Carson, Culley C; Wilson, Steven K; Wiygul, Jeremy; Tornehl, Chris; Cleves, Mario A; Simmons, Caroline J; Donatucci, Craig F

2008-01-01

Positive cultures, visible biofilm and confocal micrography confirm bacterial presence on clinically uninfected inflatable penile prostheses at revision surgery. Salvage irrigation has been proved to rescue patients with clinically infected inflatable penile prostheses. Similar washout at revision for noninfectious reasons significantly lowers subsequent infection rates. We investigated a larger series of patients for positive culture rates and evaluated implant capsule tissue culture rates before and after revision washout. At 4 institutions a total of 148 patients with inflatable penile prostheses underwent revision surgery for noninfectious reasons between June 2001 and September 2005. Swab cultures of the fluid around the pump and visible biofilm were obtained. Also, in 65 patients a wedge of tissue from the capsule that forms around the pump was cultured. After implant removal revision washout of the implant spaces was performed and a second wedge of tissue was cultured. Of the 148 patients 97 (66%) had positive bacterial swab cultures of the fluid around the pump or biofilm. A total of 124 isolates were cultured. Of the 65 implant capsule tissue cultures obtained before washout 28 (43%) were positive for bacteria, while 16 (25%) obtained after revision washout were positive. Positive cultures and visible bacterial biofilm are present on clinically uninfected inflatable penile prostheses at revision surgery in most patients. Revision washout appears to decrease the bacterial load on implant capsule tissue at revision surgery of inflatable penile prostheses for noninfectious reasons.

High proximal migration in cemented acetabular revisions operated with bone impaction grafting; 47 revision cups followed with RSA for 17 years.

Science.gov (United States)

Mohaddes, Maziar; Herberts, Peter; Malchau, Henrik; Johanson, Per-Erik; Kärrholm, Johan

2017-05-12

Bone impaction grafting is a biologically and mechanically appealing option in acetabular revision surgery, allowing restitution of the bone stock and restoration of the biomechanics. We analysed differences in proximal migration of the revision acetabular components when bone impaction grafting is used together with a cemented or an uncemented cup. 43 patients (47 hips), revised due to acetabular loosening and judged to have less than 50% host bone-implant contact were included. The hips were randomised to either an uncemented (n = 20) or a cemented (n = 27) revision cup. Radiostereometry and radiography was performed postoperatively, at 3 and 6 months, 1, 2, 3, 5, 7, 10 and 13 and 17 years postoperatively. Clinical follow-up was performed at 1, 2 and 5 years postoperatively and thereafter at the same interval as in the radiographic follow-up. There were no differences in the base line demographic data between the 2 groups. At the last follow-up (17 years) 14 hips (10 cemented, 4 uncemented) had been re-revised due to loosening. 3 additional cups (1 uncemented and 2 cemented) were radiographically loose. There was a higher early proximal migration in the cemented cups. Cups operated on with cement showed a higher early migration measured with RSA and also a higher number of late revisions. The reason for this is not known, but factors such as inclusion of cases with severe bone defects, use of smaller bone chips and issues related to the impaction technique might have had various degrees of influence.

RCBI-II: The Second Revision of the Revised Cyber Bullying Inventory

Science.gov (United States)

Topcu, Çigdem; Erdur-Baker, Özgür

2018-01-01

The aim of this study is to update the Turkish version of the Revised Cyber Bullying Inventory (RCBI) and eliminate specific technology names. Validity and reliability tests were carried out with 1,803 high school students. The updated version of the RCBI yields valid and reliable scores measuring cyberbullying and victimization.

Tumor Suppressor RARRES1 Regulates DLG2, PP2A, VCP, EB1, and Ankrd26

Directory of Open Access Journals (Sweden)

Ziad J. Sahab, Michael D. Hall, Lihua Zhang, Amrita K. Cheema, Stephen W. Byers

2010-01-01

Full Text Available Retinoic Acid Receptor Responder (RARRES1 initially identified as a novel retinoic acid receptor regulated gene in the skin is a putative tumor suppressor of unknown function. RARRES1 was knocked down in immortalized human prostatic epithelial cell line PWR-1E cells and differential protein expression was identified using differential in-gel electrophoresis (DIGE followed by matrix-assisted laser desorption ionization (MALDI mass spectrometry and western Blot analysis excluding highly abundant proteins routinely identified in almost all proteomics projects. Knock-down of RARRES1: 1- down-regulates PP2A, an enzyme involved in the negative regulation of the growth hormone-stimulated signal transduction pathways; 2- down-regulates Valosin-containing protein causing impaired autophagy; 3- up-regulates the tumor suppressor disks large 2; 4- up-regulates Ankrd26 that belongs to the POTE family of genes that are highly expressed in cancer patients with poor outcome; and 5- down-regulates EB1, a protein that is involved in spindle dynamics and chromosome alignment during mitosis.

Methods for implementing revisions to emergency operating procedures. Final report

International Nuclear Information System (INIS)

Myers, L.B.; Bell, A.J.

1984-05-01

In response to the Three Mile Island (TMI) accident, the US Nuclear Regulatory Commission (NRC) has published the TMI Action Plan. The TMI Action Plan Item I.C.1 called for the upgrading of Emergency Operating Procedures (EOPs) at nuclear power plants. The program developed from this Action Plan item has resulted in utility efforts to: (1) revise EOPs; (2) train personnel in the use of the EOPs; and (3) implement the revised EOPs. The NRC supported the study presented in this report to identify factors which influence the effectiveness of training and implementation of revised EOPs. The NRC's major concern was the possible effects of negative transfer of training. The report includes a summary of existing methods for implementing revisions to procedures based on interviews of plant personnel, a review of the training literature applicable to the effect of previously learned procedures on the learning of and performance with revised procedures (i.e., negative transfer) and recommendations of methods and schedules for implementing revised EOPs. While the study found that the concern over negative transfer of training was not as great as anticipated, several recommendations were made. These include: (1) overtraining of operators to reduce the effect of observed negative transfer; and (2) implementation of the revised EOPs as soon as possible after training to minimize the time operators must rely upon the old EOPs after having been trained on the revised EOPs. The results of the study should be useful both to the utilities and the NRC in the development and review of EOP implementation programs