WorldWideScience

Sample records for ea final guidance

  1. Final OSWER Vapor Intrusion Guidance

    Science.gov (United States)

    EPA is preparing to finalize its guidance on assessing and addressing vapor intrusion, which is defined as migration of volatile constituents from contaminated media in the subsurface (soil or groundwater) into the indoor environment. In November 2002, EPA issued draft guidance o...

  2. 75 FR 62133 - Notice of Availability of Final Environmental Assessment (FINAL EA) and a Finding of No...

    Science.gov (United States)

    2010-10-07

    ... Availability of Final Environmental Assessment (FINAL EA) and a Finding of No Significant Impact (FONSI) for... Environmental Assessment (FINAL EA) for Land Purchase, Access Road Construction and Access Tunnel Construction... HUMAN SERVICES Centers for Disease Control and Prevention Notice of Availability of Final...

  3. 76 FR 71619 - Availability of the Final Environmental Assessment (EA) and Finding of No Significant Impact...

    Science.gov (United States)

    2011-11-18

    ... concluded that there would be no significant short-term, long-term, or cumulative effects to the environment... discussion of existing SpaceX activities. The resource areas considered in the Final EA include air quality..., and cultural resources; hazardous materials, pollution prevention, and solid waste; light...

  4. 76 FR 63676 - Final Division of Safety Systems Interim Staff Guidance DSS-ISG-2010-01: Staff Guidance Regarding...

    Science.gov (United States)

    2011-10-13

    ... COMMISSION Final Division of Safety Systems Interim Staff Guidance DSS-ISG- 2010-01: Staff Guidance Regarding... final Division of Safety Systems Interim Staff Guidance, (DSS-ISG) DSS- ISG-2010-01, ``Staff Guidance... guidance to the NRC staff reviewer to address the increased complexity of recent spent fuel pool...

  5. 78 FR 65606 - Availability of the Final Environmental Assessment (EA) and a Finding of No Significant Impact...

    Science.gov (United States)

    2013-11-01

    ... Significant Impact (FONSI) of the J. Phil Campbell, Sr., National Resource Conservaton Center (JPC-NRCC... land and real estate at the JPC-NRCC in Watkinsville, Georgia, to the Board of Regents of the... the FONSI. Copies of the Final EA and FONSI for the JPC-NRCC Land Transfer are also available...

  6. Final Environmental Assessment (EA) for Headquarters Building Construction and Main Gate Reconfiguration White Bluff, Spokane, Washington

    Science.gov (United States)

    2012-12-01

    falcon Falco peregrinus SOC S Mammals Long-eared myotis Myotis evotis SOC None Townsend’s big-eared bat Corynorhinus townsendii pallescens SOC C...noted during interviews with WB personnel. The underlayment and insulation in buildings that include flat gravel-style roofs was reported to include...Bluff Environmental Assessment (EA) Page 3-14 prove otherwise, it is generally considered that all building materials other than wood , steel, or glass

  7. 75 FR 63823 - Final Guidance, “Federal Greenhouse Gas Accounting and Reporting”

    Science.gov (United States)

    2010-10-18

    ... Leadership in Environmental, Energy, and Economic Performance.'' 74 FR 52117, Oct. 8, 2009. The purpose of... QUALITY Final Guidance, ``Federal Greenhouse Gas Accounting and Reporting'' AGENCY: Council on... agency operations. This Final Guidance, ``Federal Greenhouse Gas Accounting and Reporting,'' is...

  8. 76 FR 26177 - National Organic Program: Notice of Final Guidance for Accredited Certifying Agents and Certified...

    Science.gov (United States)

    2011-05-06

    ... four final guidance documents are entitled as follows: ``Compost and Vermicompost in Organic Crop... vermicompost, wild crop harvesting, outdoor access for poultry, commingling and contamination prevention, and... final: ``NOP 5021--Compost and Vermicompost in Organic Crop Production''; ``NOP 5022--Wild...

  9. TRIAL AND TESTING OF AN EXPERIMENTAL GUIDANCE CURRICULUM. FINAL REPORT.

    Science.gov (United States)

    SHERMAN, VIVIAN S.

    INNOVATIVE VOCATIONAL GUIDANCE CURRICULUM MATERIALS WERE DESIGNED TO INCREASE SELF-UNDERSTANDING AND MOTIVATION RELATIVE TO CAREER EXPLORATION AND PLANNING. THESE MATERIALS STEMMED ORIGINALLY FROM A SURVEY OF ATTITUDES AND PLANNING RELATIVE TO CAREER DEVELOPMENT IN THE PALO ALTO UNIFIED SCHOOL DISTRICT. THE RESEARCH DATA WAS USED AS CURRICULUM…

  10. 76 FR 41157 - Guidance for Industry: Questions and Answers Regarding the Final Rule, Prevention of Salmonella...

    Science.gov (United States)

    2011-07-13

    ... Answers Regarding the Final Rule, Prevention of Salmonella Enteritidis in Shell Eggs During Production... Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation'' (the draft guidance... rule entitled ``Prevention of Salmonella Enteritidis in Shell Eggs During Production, Storage,...

  11. FDA Issues Final Guidance Clarifying FDA and EPA Jurisdiction over Mosquito-Related Products

    Science.gov (United States)

    FDA finalized guidance to provide information on FDA and EPA jurisdiction over the regulation of mosquito-related products intended to function as pesticides, including those products intended to function as pesticides

  12. 76 FR 17160 - Office of New Reactors; Final Interim Staff Guidance on the Review of Nuclear Power Plant Designs...

    Science.gov (United States)

    2011-03-28

    ... COMMISSION Office of New Reactors; Final Interim Staff Guidance on the Review of Nuclear Power Plant Designs... Guidance (ISG) DC/COL-ISG-021 titled ``Interim Staff Guidance on the Review of Nuclear Power Plant Designs... Nuclear Power Plants,'' March 2007, Standard Review Plan (SRP), Section 8.3.1 and Sections 9.5.4 through...

  13. 77 FR 23713 - Pesticides; Final Guidance on Material Safety Data Sheets as Pesticide Labeling; Request for...

    Science.gov (United States)

    2012-04-20

    ... relationship between EPA-approved labels for pesticides registered under the Federal Insecticide, Fungicide... AGENCY Pesticides; Final Guidance on Material Safety Data Sheets as Pesticide Labeling; Request for.... SUMMARY: The Agency is announcing the availability of a Pesticide Registration Notice (PR Notice)...

  14. Audit and Evaluation of the Georgia Comprehensive Career Guidance Project, Grades 7-12. Final Report.

    Science.gov (United States)

    Walz, Garry R.; Benjamin, Libby

    An external evaluation was conducted to assess the training packages developed by the Georgia Comprehensive Career Guidance Project (see CE 018 130 for the final report of this project). Three secondary staff development training packages (Educational Environment, CE 018 154; Work and Leisure Environments, CE 018 161; and Human Relations, CE 018…

  15. 77 FR 65728 - Final Interim Staff Guidance Augmenting NUREG-1537, “Guidelines for Preparing and Reviewing...

    Science.gov (United States)

    2012-10-30

    ... COMMISSION Final Interim Staff Guidance Augmenting NUREG-1537, ``Guidelines for Preparing and Reviewing... Staff Guidance (ISG), that augments NUREG- 1537, Part 1, ``Guidelines for Preparing and Reviewing Applications for the Licensing of Non-Power Reactors: Format and Content,'' and NUREG- 1537, Part...

  16. 76 FR 56973 - Office of National Marine Sanctuaries Final Policy and Permit Guidance for Submarine Cable Projects

    Science.gov (United States)

    2011-09-15

    ... Policy and Permit Guidance for Submarine Cable Projects AGENCY: Office of National Marine Sanctuaries...) has developed final policy and permitting guidance for submarine cable projects proposed in national... install and maintain submarine cables in sanctuaries are reviewed consistently and in a manner...

  17. 76 FR 17159 - Office of New Reactors; Final Interim Staff Guidance on Standard Review Plan, Section 17.4...

    Science.gov (United States)

    2011-03-28

    .... SUMMARY: The NRC staff is issuing its Final Interim Staff Guidance (ISG) DC/COL-ISG-018 (Agencywide... of ] the design certification (DC) and combined license (COL) applications. The NRC staff issues DC/COL-ISGs to facilitate timely implementation of current staff guidance and to facilitate...

  18. Investigation of EAS cores

    Science.gov (United States)

    Shaulov, S. B.; Beyl, P. F.; Beysembaev, R. U.; Beysembaeva, E. A.; Bezshapov, S. P.; Borisov, A. S.; Cherdyntceva, K. V.; Chernyavsky, M. M.; Chubenko, A. P.; Dalkarov, O. D.; Denisova, V. G.; Erlykin, A. D.; Kabanova, N. V.; Kanevskaya, E. A.; Kotelnikov, K. A.; Morozov, A. E.; Mukhamedshin, R. A.; Nam, R. A.; Nesterova, N. M.; Nikolskaya, N. M.; Pavluchenko, V. P.; Piskal, V. V.; Puchkov, V. S.; Pyatovsky, S. E.; Ryabov, V. A.; Sadykov, T. Kh.; Schepetov, A. L.; Smirnova, M. D.; Stepanov, A. V.; Uryson, A. V.; Vavilov, Yu. N.; Vildanov, N. G.; Vildanova, L. I.; Zayarnaya, I. S.; Zhanceitova, J. K.; Zhukov, V. V.

    2017-06-01

    The development of nuclear-electromagnetic cascade models in air in the late forties have shown informational content of the study of cores of extensive air showers (EAS). These investigations were the main goal in different experiments which were carried out over many years by a variety of methods. Outcomes of such investigations obtained in the HADRON experiment using an X-ray emulsion chamber (XREC) as a core detector are considered. The Ne spectrum of EAS associated with γ-ray families, spectra of γ-rays (hadrons) in EAS cores and the Ne dependence of the muon number, ⟨Nμ⟩, in EAS with γ-ray families are obtained for the first time at energies of 1015-1017 eV with this method. A number of new effects were observed, namely, an abnormal scaling violation in hadron spectra which are fundamentally different from model predictions, an excess of muon number in EAS associated with γ-ray families, and the penetrating component in EAS cores. It is supposed that the abnormal behavior of γ-ray spectra and Ne dependence of the muon number are explained by the emergence of a penetrating component in the 1st PCR spectrum `knee' range. Nuclear and astrophysical explanations of the origin of the penetrating component are discussed. The necessity of considering the contribution of a single close cosmic-ray source to explain the PCR spectrum in the knee range is noted.

  19. Investigation of EAS cores

    Directory of Open Access Journals (Sweden)

    Shaulov S.B.

    2017-01-01

    Full Text Available The development of nuclear-electromagnetic cascade models in air in the late forties have shown informational content of the study of cores of extensive air showers (EAS. These investigations were the main goal in different experiments which were carried out over many years by a variety of methods. Outcomes of such investigations obtained in the HADRON experiment using an X-ray emulsion chamber (XREC as a core detector are considered. The Ne spectrum of EAS associated with γ-ray families, spectra of γ-rays (hadrons in EAS cores and the Ne dependence of the muon number, ⟨Nμ⟩, in EAS with γ-ray families are obtained for the first time at energies of 1015–1017 eV with this method. A number of new effects were observed, namely, an abnormal scaling violation in hadron spectra which are fundamentally different from model predictions, an excess of muon number in EAS associated with γ-ray families, and the penetrating component in EAS cores. It is supposed that the abnormal behavior of γ-ray spectra and Ne dependence of the muon number are explained by the emergence of a penetrating component in the 1st PCR spectrum ‘knee’ range. Nuclear and astrophysical explanations of the origin of the penetrating component are discussed. The necessity of considering the contribution of a single close cosmic-ray source to explain the PCR spectrum in the knee range is noted.

  20. International Conference on Vocational Guidance (6th, Hyogo, Japan, November 2-4, 1988). Final Report.

    Science.gov (United States)

    Ashiya Univ., Hyogo (Japan).

    This conference report contains the following papers: "Keynote Address" (Fukuyama); "Predictions Regarding the Nature and Significance of Vocational Guidance during the 21st Century in the United States" (Hoyt); "The Changing Workforce and Vocational Guidance" (Inaba); "The 6th International Conference on…

  1. 77 FR 50372 - Guidance for Industry: Questions and Answers Regarding the Final Rule, Prevention of Salmonella...

    Science.gov (United States)

    2012-08-21

    ... HUMAN SERVICES Food and Drug Administration 21 CFR Parts 16 and 118 Guidance for Industry: Questions and... rule, including questions and answers on compliance dates; coverage; definitions; SE prevention... confer any rights for or on any person and does not operate to bind FDA or the public. An alternate...

  2. Career Information System Project: "Supermarket" Guidance System Conceptual Model for Suburban Community Colleges. Final Report.

    Science.gov (United States)

    Foothill Coll., Los Altos Hills, CA.

    This publication documents one community college's experience in setting up a "supermarket" guidance system model. Its goals were to maximize the number and kinds of available services, and make them maximally accessible to all students. A commercial design firm was hired to analyze the school's present and future requirements. A computer…

  3. Online Trajectory Reshaping for a Launch Vehicle to Minimize the Final Error Caused by Navigation and Guidance

    Directory of Open Access Journals (Sweden)

    Tessy Thomas

    2013-05-01

    Full Text Available Autonomous launch vehicles, once lifted off from the launch pad, equipped with an onboard intelligence which aids in achieving the mission objectives with high accuracy. The accuracy of the mission depends basically on navigation and guidance errors caused at burnout condition, after which the vehicle follows an elliptical path upto impact. The paper describes how to handle the final impact and injection error caused by these navigation and guidance errors. In the current work the initial burnout conditions are tuned and corrected such that the terminal impact point is achieved within the desired tolerance bounds. A two point boundary value problem is solved using the gradient method, for determining the impact errors. The algorithm is validated by simulation studies for various burnout conditions.Defence Science Journal, 2013, 63(3, pp.254-261, DOI:http://dx.doi.org/10.14429/dsj.63.2414

  4. Online Trajectory Reshaping for a Launch Vehicle to Minimize the Final Error Caused by Navigation and Guidance

    Directory of Open Access Journals (Sweden)

    Tessy Thomas

    2013-05-01

    Full Text Available Autonomous launch vehicles, once lifted off from the launch pad, equipped with an onboard intelligence which aids in achieving the mission objectives with high accuracy. The accuracy of the mission depends basically on navigation and guidance errors caused at burnout condition, after which the vehicle follows an elliptical path upto impact. The paper describes how to handle the final impact and injection error caused by these navigation and guidance errors. In the current work the initial burnout conditions are tuned and corrected such that the terminal impact point is achieved within the desired tolerance bounds. A two point boundary value problem is solved using the gradient method, for determining the impact errors. The algorithm is validated by simulation studies for various burnout conditions.

  5. Specialty preferences among final year medical students in medical schools of southeast Nigeria: need for career guidance.

    Science.gov (United States)

    Ossai, Edmund Ndudi; Uwakwe, Kenechi Anderson; Anyanwagu, Uchenna Chidi; Ibiok, Ntat Charles; Azuogu, Benedict Ndubueze; Ekeke, Ngozi

    2016-10-04

    In resource-poor settings with low doctor-population ratio, there is need for equitable distribution of healthcare workforce. The specialty preferences of medical students determine the future composition of physician workforce hence its relevance in career guidance, healthcare planning and policy formulation. This study was aimed at determining the specialty preferences of final year medical students in medical schools of southeast Nigeria, the gender differences in choice of specialty and the availability of career guidance to the students during the period of training. A descriptive cross-sectional study was conducted among final year medical students in the six accredited medical schools in southeast Nigeria using self-administered semi-structured questionnaire. Information on reason for studying Medicine, specialty preference and career guidance were obtained. Chi-square test of statistical significance was used in the analysis. A total of 457 students participated in the study with a response rate of 86.7 %. The mean age was 25.5 ± 2.9 years and 57.1 % were male. Majority (51 %) opted to study Medicine in-order to save lives while 89.5 % intended to pursue postgraduate medical training. A higher proportion (51.8 %) made the decision during the period of clinical rotation. The five most preferred specialties among the students were Surgery (24.0 %); Paediatrics (18.8 %); Obstetrics and Gynaecology (15.6 %); Internal Medicine (11.0 %) and Community Medicine (6.8 %) while Pathology (2.0 %); Anaesthesia (0.7 %) and Ear, Nose and Throat (0.2 %), were the least preferred. Compared to females, a higher proportion of male students intended to specialise in Surgery (32.3 % vs 13.0 %, p career guidance during their stay in medical school and 11.2 % were undecided on choice of specialty. In spite of the high proportion of students willing to pursue specialist medical training after graduation, most opted for the four core clinical specialities of

  6. Comparison of US. Military and International Electromagnetic Compatibility Guidance. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Ewing, P. D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Wood, R. T. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Antonescu, C. E. [Nuclear Regulatory Commission (NRC), Washington, DC (United States)

    2003-08-31

    The Oak Ridge National Laboratory (ORNL) has been engaged by the U.S. Nuclear Regulatory Commission (NRC) Office of Nuclear Regulatory Research to assist in developing the technical basis for regulatory guidance on electromagnetic interference (EMI) and radio-frequency interference (RFI) immunity and power surge withstand capability (SWC). Previous research has provided recommendations on electromagnetic compatibility (EMC) design and installation practices, endorsement of EMII/RFI immunity and SWC test criteria and test methods, and determination of ambient electromagnetic conditions at nuclear power plants. These recommendations have been incorporated into the technical basis for guidance in addressing EMI/RFI and power surges in safety-related instrumentation and control (I&C) systems in nuclear power plants. The recommendations by the ORNL staff on test criteria, test methods, and operating envelopes were significantly influenced by the military standards issued by the U.S. Department of Defense (DOD). That is the case because until recently there were no comprehensive commercial standards that covered EMI/RFI immunity. The present research involves reviewing and assessing the commercial standards issued by the International Electrotechnical Commission (IEC) and endorsed by the European Union in the last few years. This document reports the results of a study performed by the ORNL staff comparing Regulatory Guide 1.180, the U.S. military standards, and international EMC guidance.

  7. EAS Telecommunications Certification Bodies (TCB)

    Data.gov (United States)

    Federal Communications Commission — EAS (Equipment Authorization System). A Telecommunication Certification Body (TCB) is an accredited product certification body with the authority to issue Grants of...

  8. 75 FR 75607 - Notice of Availability of Final Interpretative Guidance-Sharing Suspicious Activity Reports by...

    Science.gov (United States)

    2010-12-03

    ... organizational structure for purposes consistent with Title II of the BSA, as determined by regulation or... organizational structure for purposes consistent with Title II of the BSA, as determined by regulation or... their corporate organizational structure. In the final rule text published separately in today's Federal...

  9. 78 FR 6149 - Final Interim Staff Guidance Assessing the Radiological Consequences of Accidental Releases of...

    Science.gov (United States)

    2013-01-29

    ... supplements NUREG-0800 Standard Review Plan (SRP) Section 11.2 and Branch Technical Position 11-6 and ISG-014... contained in NUREG-0800, SRP dated March 2007. The NRC staff intends to incorporate these final ISGs into the next revision of RG 1.206 and NUREG-0800. On February 24, 2010 (75 FR 8411 and 75 FR 8412),...

  10. EAS Equipment Authorization Grantee Registrations

    Data.gov (United States)

    Federal Communications Commission — EAS (Equipment Authorization System). Radio Frequency (RF) devices are required to be properly authorized under 47 CFR Part 2 prior to being marketed or imported...

  11. EA 18G Growler Aircraft (EA 18G)

    Science.gov (United States)

    2015-12-01

    are no significant software-related issues with this program at this time. EA-18G December 2015 SAR March 17, 2016 12:07:44 UNCLASSIFIED 7 APB...quantities, and funding for each delivery or task order issued under this IDIQ contract are individually negotiated. This contract includes shared costs and...maintenance will follow the directives as EA-18G December 2015 SAR March 17, 2016 12:07:44 UNCLASSIFIED 37 published in the ILS, SCM and F414 support

  12. Nonlinear analysis of EAS clusters

    CERN Document Server

    Zotov, M Yu; Fomin, Y A; Fomin, Yu. A.

    2002-01-01

    We apply certain methods of nonlinear time series analysis to the extensive air shower clusters found earlier in the data set obtained with the EAS-1000 Prototype array. In particular, we use the Grassberger-Procaccia algorithm to compute the correlation dimension of samples in the vicinity of the clusters. The validity of the results is checked by surrogate data tests and some additional quantities. We compare our conclusions with the results of similar investigations performed by the EAS-TOP and LAAS groups.

  13. Issuance of Final Guidance: Ecological Risk Assessment and Risk Management Principles for Superfund Sites, October 7, 1999

    Science.gov (United States)

    This guidance is intended to help Superfund risk managers make ecological risk management decisions that are based on sound science, consistent across Regions, and present a characterization of site risks that is transparent to the public.

  14. Specifications of EA-BRACHI

    Energy Technology Data Exchange (ETDEWEB)

    Taguchi, Mitsumasa; Namba, Hideki; Aoki, Yasushi; Watanabe, Ritsuko; Matsumoto, Yuuichi; Watanabe, Hiroshi [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    1996-11-01

    EA-BRACHI (Experimental Apparatus for Basic study of Radiation Chemistry with Heavy Ions) has been constructed at a vertical port of AVF cyclotron in TIARA (Takasaki Ion Accelerators for Advanced Radiation Application) facility. This apparatus is used for measurement of the spatial distribution of energy deposited around the ion`s path, and the reaction of radicals and other intermediates produced by heavy ion irradiation in solid and liquid samples. This report detailed specifications and performance of this apparatus, including operational procedures and some basic data. (author)

  15. 77 FR 43405 - Final Standard Review Plan, Branch Technical Position 7-19 on Guidance for Evaluation of...

    Science.gov (United States)

    2012-07-24

    ... and Defense-in-Depth in Digital Computer-Based Instrumentation and Control Systems AGENCY: Nuclear... ``Guidance for Evaluation of Diversity and Defense-in-Depth in Digital Computer-Based Instrumentation and Control Systems.'' This BTP is to be cited as the acceptance criteria for Diversity and...

  16. 7 CFR 1955.136 - Environmental Assessment (EA) and Environmental Impact Statement (EIS).

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 14 2010-01-01 2009-01-01 true Environmental Assessment (EA) and Environmental Impact... Disposal of Inventory Property General § 1955.136 Environmental Assessment (EA) and Environmental Impact Statement (EIS). (a) Prior to a final decision on some disposal actions, an environmental assessment must be...

  17. OneVA EA Vision and Strategy

    Data.gov (United States)

    Department of Veterans Affairs — The outcomes/goals supported by effective use of an EA are: Improved Service Delivery, Functional Integration, Resource Optimization and Authoritative Reference. VA...

  18. Search Radar ECM/EA Simulator

    Data.gov (United States)

    Federal Laboratory Consortium — FUNCTION: Tests the effectiveness of electronic countermeasures/electronic attack (ECM/EA) equipment and techniques for jamming airborne search and targeting radars....

  19. EAS Test Firm Accrediting Bodies (TFAB)

    Data.gov (United States)

    Federal Communications Commission — EAS (Equipment Authorization System). The accreditation bodies for testing laboratories are referred to as Test Firm Accrediting Bodies (TFABs). They are responsible...

  20. 24 CFR 50.31 - The EA.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false The EA. 50.31 Section 50.31 Housing and Urban Development Office of the Secretary, Department of Housing and Urban Development PROTECTION AND ENHANCEMENT OF ENVIRONMENTAL QUALITY Environmental Assessments and Related Reviews § 50.31 The EA...

  1. EAS 2.948 Listed Test Firms

    Data.gov (United States)

    Federal Communications Commission — EAS (Equipment Authorization System). The following firms have submitted the information required by Section 2.948 of the FCC Rules for measuring devices subject to...

  2. Multiple shell shower fronts in EAS with ARGO-YBJ

    Directory of Open Access Journals (Sweden)

    Marsella G.

    2015-01-01

    Full Text Available The ARGO-YBJ experiment is an Extensive Air Shower array that has been operated at the high altitude Yangbajing Cosmic Ray Laboratory (Tibet, P.R. China 4300 m a.s.l. in its final configuration since December 2007 until February 2013. The detector consists of a dense layer of Resistive Plate Counters (RPCs covering an area of about 11000 m2. It has been designed to measure the temporal and spatial structure of Extensive Air Showers (EAS with high space-time resolution. The detector gives a quite highly detailed picture of shower footprints at ground. It is perfectly suitable to understand the EAS morphology. These detector characteristics have been used for seeking particles of large rest mass produced in cosmic rays by measuring the Multiple Shell Shower Fronts relative delays. The technique and preliminary results will be illustrated in the present work.

  3. The dependence of proton correlations on integral characteristics of eA interactions

    Energy Technology Data Exchange (ETDEWEB)

    Degtyarenko, P.V. (ITEP, Moscow (Russian Federation)); Doroshkevich, E.A. (ITEP, Moscow (Russian Federation)); Efremenko, Yu.V. (ITEP, Moscow (Russian Federation)); Gavrilov, V.B. (ITEP, Moscow (Russian Federation)); Kossov, M.V. (ITEP, Moscow (Russian Federation)); Leksin, G.A. (ITEP, Moscow (Russian Federation)); Stavinsky, A.V. (ITEP, Moscow (Russian Federation)); Vlassov, A.V. (ITEP, Moscow (Russian Federation))

    1994-12-01

    We report the results of analysis of correlations of the product protons from inelastic eA collisions at small Q[sup 2]. The experimental data were measured by the ARGUS detector. The correlation effect at small relative momenta q (interference and final state interaction) is closely associated with the angular correlations due to momentum conservation. The examined correlations in eA collisions also show features similar to correlations in hA collisions. (orig.)

  4. The dependence of proton correlations on integral characteristics of eA interactions

    Science.gov (United States)

    Degtyarenko, P. V.; Doroshkevich, E. A.; Efremenko, Yu. V.; Gavrilov, V. B.; Kossov, M. V.; Leksin, G. A.; Stavinsky, A. V.; Vlassov, A. V.

    1994-09-01

    We report the results of analysis of correlations of the product protons from inelastic eA collisions at small Q 2. The experimental data were measured by the ARGUS detector. The correlation effect at small relative momenta q (interference and final state interaction) is closely associated with the angular correlations due to momentum conservation. The examined correlations in eA collisions also show features similar to correlations in hA collisions.

  5. EA Training 2.0 Newsletter #3 - EA Active, Problem Based Learning Methodology

    DEFF Research Database (Denmark)

    Buus, Lillian; Ryberg, Thomas; Sroga, Magdalena

    2010-01-01

    The main products of the project are innovative, active problem-based learning methodology for EA education and training, EA courses for university students and private and public sector employees, and an Enterprise Architecture competence ontology including a complete specification of skills...

  6. Time dispersion of muons in EAS

    Energy Technology Data Exchange (ETDEWEB)

    Blake, P.R.; Collis, V.S.; Luksys, M.; Nash, W.F.; Sephton, A.J. (Nottingham Univ. (UK). Dept. of Physics)

    1990-05-01

    This paper describes the results and conclusions from an experiment set up to measure the time spread of muons in extensive air showers (EAS) detected at the Haverah Park EAS detector array, UK. The pulse risetimes (T{sub 70}) from 10% to 70% amplitude of the responses from 3 x 10 m{sup 2} muon detectors are studied, and the anomalous pulse structure is investigated. The mean T{sub 70} is studied as a function of shower size, zenith angle and core distance and its dependence on shower size is related to the elongation length of the EAS. Fluctuations in T{sub 70} are studied as a method of yielding the mass composition of the primary particles. (author).

  7. International Conference on Harmonisation; final recommendations on the revision of the permitted daily exposures for two solvents, n-methylpyrrolidone and tetrahydrofuran, according to the maintenance procedures for the guidance Q3C Impurities: Residual Solvents; Availability. Notice.

    Science.gov (United States)

    2003-11-13

    The Food and Drug Administration (FDA) is announcing final recommendations to revise the permitted daily exposures (PDEs) for two solvents, n-methylpyrrolidone (NMP) and tetrahydrofuran (THF), according to the maintenance procedures for the guidance for industry entitled "Q3C Impurities: Residual Solvents." The final recommendations were reached under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH).

  8. EAS selection in the EMMA underground array

    DEFF Research Database (Denmark)

    Sarkamo, J.; Bezrukov, L.; Enqvist, T.

    2013-01-01

    The first measurements of the Experiment with MultiMuon Array (EMMA) have been analyzed for the selection of the Extensive Air Showers (EAS). Test data were recorded with an underground muon tracking station and a satellite station separated laterally by 10 metres. Events with tracks distributed...

  9. Distribution of EAS arrival times according to data of the EAS-1000 prototype array

    CERN Document Server

    Fomin, Yu A; Kulikov, G V; Solovyeva, V I; Sulakov, V P; Vedeneev, O V; Zotov, M Yu; Fomin, Yu. A.

    2002-01-01

    We have analysed arrival times of extensive air showers (EAS) registered with the EAS-1000 prototype array during the period from August, 1997 till February, 1999. Our analysis has revealed that though the vast majority of samples of consecutive time intervals between EAS arrival times obey the exponential distribution, there are sequences of showers that have another distribution and thus violate the homogeneity hypothesis. The search for correlation between such events and clusters of showers and events with big delays between arrival times was also carried out.

  10. EAS data at the mountain level and a shape of the CR spectrum beyond the break

    CERN Document Server

    Shaulov, S B

    2016-01-01

    In the most works which deal with EAS the CR energy spectrum is deduced by means of the model defined dependence $E_0=a\\cdot{N_e}^{\\alpha}$. An electron total number $N_e$ is evaluated by integration of the NKG-function f(r). This algorithm breaks down for young EAS with age parameter $s\\sim0$. This work shows, that part of the young EAS becomes large in the range $N_e\\geq10^7$, it cause to divergency of the $N_e$ integral for them and distorts the shape of EAS (CR) spectrum. A final analysis of the experimental data permits to conclude that EAS spectrum has local maximum at $N_e\\sim10^9$, which results in a decrease of the EAS spectrum slope for $N_e\\geq10^7$ (inverse break or "knee"). A local maximum can arise because of the additional CR component in the range $E_0\\geq10$ PeV.

  11. EAS thermal neutron lateral and temporal distributions

    CERN Document Server

    Stenkin, Yu V; Petrukhin, A A; Shchegolev, O B; Stepanov, V I; Volchenko, V I; Yashin, I I; Zadeba, E A

    2015-01-01

    A novel type of EAS array (PRISMA-32) has been constructed on the base of NEVOD-DECOR experiment (MEPhI,Moscow) and is now taking data. It consists of 32 specially designed scintillator en-detectors able to measure two main EAS components: hadrons (n) and electrons (e). First results on thermal neutron lateral as well as temporal distributions are presented. Obtained exponential neutron lateral distributions are consistent with that expected for normal hadron production with exponential transverse momentum distribution. As there are no other experimental data on thermal neutron distributions and so, to compare results with other measurements, we additionally obtained electron lateral distribution function (using the same detectors) and compared it with NKG - function. Recorded neutron temporal distributions are very close to that obtained with data of our previous prototypes.

  12. Lifelong Guidance

    National Research Council Canada - National Science Library

    Noworol, Czesław

    2011-01-01

    .... Career guidance refers to services and activities intended to assist individuals, of any age and at any point throughout their lives, to make educational, training and occupational choices and to manage their careers...

  13. D1.1 Stakeholders Needs Regarding EA

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Eleftheriou, Paraskevi; Maglavera, Stavroula

    2009-01-01

    in a university course about EA. This deliverable commences with a detailed description of the methodology followed for the identification of stakeholders needs regarding Enterprise Architecture (EA) training and education. It then presents the results of the methodology application in terms of EA related...

  14. International Conference on Harmonisation; final recommendation for the revision of the permitted daily exposure for the solvent cumene according to the maintenance procedures for the guidance Q3C Impurities: Residual Solvents; availability. Notice.

    Science.gov (United States)

    2012-02-23

    The Food and Drug Administration (FDA) is announcing the availability of a final recommendation for the revision of the permitted daily exposure (PDE) for the solvent cumene according to the maintenance procedures for the guidance for industry entitled ``Q3C Impurities: Residual Solvents.'' The recommendation was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH).

  15. Clusters of EAS with electron number >~ 10^4

    CERN Document Server

    Fomin, Y A; Zotov, M Yu; Fomin, Yu. A.

    2002-01-01

    We perform cluster analysis of arrival times of extensive air showers (EAS) registered with the EAS-1000 Prototype array in the period from August, 1997 till February, 1999. We present twenty cluster events each consisting of one or several EAS clusters, study the dynamics of their development, and analyze the angular distribution of EAS in clusters. We find that there may be certain correlation between EAS clusters with mean electron number $\\sim10^5$ on the one hand and gamma-ray bursts and ultrahigh energy cosmic rays on the other.

  16. Ultrasonic versus sonic activation of the final irrigant in root canals instrumented with rotary/reciprocating files: An in-vitro scanning electron microscopy analysis

    National Research Council Canada - National Science Library

    Khalap, Neha Deepak; Kokate, Sharad; Hegde, Vibha

    2016-01-01

    ... (n = 20) where the final irrigant was activated using either Ultrasonics (Passive Ultrasonic Irrigation; PUI) or Sonics (EndoActivator; EA). Group 1: PTN + EA; Group 2: PTN + PUI; Group 3: WO + EA; and Group 4: WO + PUI...

  17. Improving Counselors' Delivery of Career Guidance/Instructional Services through Computer Technology: A. High School Study. B. University Study. Final Report.

    Science.gov (United States)

    Rozman, Frank E.; Kahl, Michael D.

    Six high schools and Millersville University implemented the microcomputerized Discover II Career Guidance system. Subjects for the high school study were 386 juniors in six high schools within a 25-mile radius of Millersville University. Subjects were divided into control, Discover/directive counseling, and Discover-only groups. Pre- and…

  18. 78 FR 25487 - Final License Renewal Interim Staff Guidance LR-ISG-2012-01: Wall Thinning Due to Erosion Mechanisms

    Science.gov (United States)

    2013-05-01

    ... Mechanisms AGENCY: Nuclear Regulatory Commission. ACTION: Interim staff guidance; issuance. SUMMARY: The U.S...), LR-ISG-2012-01, ``Wall Thinning Due to Erosion Mechanisms.'' This LR-ISG revises an NRC staff... Power Plants'' (SRP-LR), to address wall thinning due to various erosion mechanisms for piping...

  19. The Fundamental Planes of E+A galaxies and GALEX UV-excess early-type galaxies: revealing their intimate connection

    Science.gov (United States)

    Choi, Yumi; Goto, Tomotsugu; Yoon, Suk-Jin

    2009-05-01

    sequence in the final phase of the E+A to red early-type transition.

  20. Anticipatory guidance through DVD.

    Science.gov (United States)

    Franz, Sandra; McMahon, Pamela M; Calongne, Laurinda; Steele-Moses, Susan K

    2014-03-01

    The major purpose of the study was to determine if a 5-minute DVD is an effective method for communicating anticipatory guidance to parents at their child's 4-month well-child visit. A total of 84 caregivers were randomly assigned to receive anticipatory guidance through standard care (written anticipatory guidance handout and free talk) or DVD (DVD format + standard care). Participants completed a brief questionnaire immediately before and after their visit. As anticipated, knowledge scores improved significantly from pre-test to post-test. There was also a significant interaction between format used for anticipatory guidance and time. Specifically, there was greater improvement in knowledge over time for parents in the DVD group as compared with the standard care group. Additionally, the mean knowledge level of those in the DVD group as compared with those in the standard care group trended toward significance. Finally, visit length was shortened by nearly 3 minutes in the DVD group, and close to 100% of all respondents, regardless of anticipatory guidance format, indicated that they were very satisfied with their visit and amount of information learned.

  1. ERM 593 Applied Project_Guidance for Reviewing and Approving a Waste Stream Profile in the Waste Compliance and Tracking System_Final_05-05-15

    Energy Technology Data Exchange (ETDEWEB)

    Elicio, Andy U. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-05-05

    My ERM 593 applied project will provide guidance for the Los Alamos National Laboratory Waste Stream Profile reviewer (i.e. RCRA reviewer) in regards to Reviewing and Approving a Waste Stream Profile in the Waste Compliance and Tracking System. The Waste Compliance and Tracking system is called WCATS. WCATS is a web-based application that “supports the generation, characterization, processing and shipment of LANL radioactive, hazardous, and industrial waste.” The LANL generator must characterize their waste via electronically by filling out a waste stream profile (WSP) in WCATS. Once this process is completed, the designated waste management coordinator (WMC) will perform a review of the waste stream profile to ensure the generator has completed their waste stream characterization in accordance with applicable state, federal and LANL directives particularly P930-1, “LANL Waste Acceptance Criteria,” and the “Waste Compliance and Tracking System User's Manual, MAN-5004, R2,” as applicable. My guidance/applied project will describe the purpose, scope, acronyms, definitions, responsibilities, assumptions and guidance for the WSP reviewer as it pertains to each panel and subpanel of a waste stream profile.

  2. EAS-BUAP: Lateral Distribution and Performance

    Science.gov (United States)

    Salazar, H.; Martinez, O.; Cotzomi, J.; Moreno, E.; Aguilar, S.; Villaseñor, L.

    2003-07-01

    We describe the operation and performance of the first stage of the EAS-UAP extensive air shower array, as a detector of very high energy cosmic rays (Eo > 1014eV) after one year of operation. The array is located at the Campus of Puebla University, 2200 m above sea level. It consists of 10 liquid scintillator detectors, each with an active surface of 1 m2 and a detector spacing of 20 m in a square grid. One Auger Water Cherenkov detector is also included as part of the array. In this report we discuss the stability, the calibration and lateral distribution function reconstruction capabilities of the detector array. We also present the analysis of the shower size spectrum. In addition, the main characteristics of this array allow us to use it as an educational and training facility.

  3. Environmental Agents Service (EAS) Registry System of Records

    Data.gov (United States)

    Department of Veterans Affairs — The Environmental Agent Service (EAS) Registries is the information system encompassing the Ionizing Radiation Registry (IRR), the Agent Orange Registry (AOR), and...

  4. 47 CFR 11.44 - EAS message priorities.

    Science.gov (United States)

    2010-10-01

    ... Messages; second, State Messages; and third, National Information Center (NIC) Messages. (c) Key EAS... distribution of Presidential Messages. NIC messages received from national networks which are not broadcast...

  5. D1.1 Stakeholders Needs Regarding EA

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Eleftheriou, Paraskevi; Maglavera, Stavroula

    2009-01-01

    The objective of this deliverable is to identify and document the competences (skills and knowledge) that employees of both private and public sector organisations need to acquire in order to be capable of developing an EA as well as the competences that university students need to acquire...... in a university course about EA. This deliverable commences with a detailed description of the methodology followed for the identification of stakeholders needs regarding Enterprise Architecture (EA) training and education. It then presents the results of the methodology application in terms of EA related...

  6. Efficient PCA-driven EAs and metamodel-assisted EAs, with applications in turbomachinery

    Science.gov (United States)

    Kyriacou, Stylianos A.; Asouti, Varvara G.; Giannakoglou, Kyriakos C.

    2014-07-01

    This article presents methods to enhance the efficiency of Evolutionary Algorithms (EAs), particularly those assisted by surrogate evaluation models or metamodels. The gain in efficiency becomes important in applications related to industrial optimization problems with a great number of design variables. The development is based on the principal components analysis of the elite members of the evolving EA population, the outcome of which is used to guide the application of evolution operators and/or train dependable metamodels/artificial neural networks by reducing the number of sensory units. Regarding the latter, the metamodels are trained with less computing cost and yield more relevant objective function predictions. The proposed methods are applied to constrained, single- and two-objective optimization of thermal and hydraulic turbomachines.

  7. 47 CFR 11.15 - EAS Operating Handbook.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false EAS Operating Handbook. 11.15 Section 11.15... Operating Handbook. The EAS Operating Handbook states in summary form the actions to be taken by personnel.... It is issued by the FCC and contains instructions for the above situations. A copy of the Handbook...

  8. Thermophysical Properties and Spectral Characterization of EA 6043

    Science.gov (United States)

    2014-10-01

    15 3.7 FTIR Spectroscopy ................................................................................................... 18...and phosphorus-31 (31P) nuclear magnetic resonance (NMR); and Fourier transform infrared ( FTIR ) and Raman spectroscopy , were measured and are also...methylpyrophosphonate (VX pyro), a common synthesis impurity of EA 6043. Figure 12. 31P NMR spectrum of EA 6043. 18 3.7 FTIR Spectroscopy

  9. 36 CFR 1010.11 - Preparation of an EA.

    Science.gov (United States)

    2010-07-01

    ... specified in 40 CFR 1506.6. (d) Mitigated FONSI. If an EA is completed and the NEPA Compliance Coordinator... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Preparation of an EA. 1010.11 Section 1010.11 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY §...

  10. Research on Transport Properties of HFC-227ea

    Institute of Scientific and Technical Information of China (English)

    Lin Shi; Xiaojun Liu; Yuanyuan Duan; Lizhong Han; Mingshan Zhu

    2001-01-01

    HFC-227ea(1,1,1,2,3,3,3-heptafluoropropane) is considered as a promising refrigerant alternative, especially as a component in mixtures, to replace to CFC-12, HCFC-22 and R502. But reliable transport properties data for HFC-227ea are very limited. In this paper, experimental data of viscosity along the saturation line and gaseous thermal conductivity of HFC-227ea are given. The viscosity of HFC-227ea was measured with a capillary viscometer at temperatures between 263.15 K and 333.15 K along the saturation line and its uncertainty of the results is estimated to be no more than +3%. The thermal conductivity of gaseous HFC-227ea was also measured with a transient hot-wire instrument at temperatures between 259.28 K and 341.75 K and pressures up to 1.289MPa, and its uncertainty of the results is estimated to be less than +1%.

  11. 月球着陆器最终下降段的制导与控制方法研究%Guidance and Control Method for Lunar Lander's Final Descent Phase

    Institute of Scientific and Technical Information of China (English)

    胡锦昌; 张洪华

    2012-01-01

    对月球着陆器从约100m到30m之间高度的最终下降段的制导与控制方法进行了研究.提出了一种保证推力有界的简单制导方案,并从理论上严格证明了制导与姿态控制系统的几乎全局渐近稳定的性质.本文的创新之处在于:设计了嵌套饱和函数形式的特殊制导律,该制导律不仅满足主推力有界和可以防止姿态控制中的奇异问题,而且具有形式更为简单和调节着陆器的最大允许偏斜角等优点;得益于制导律的嵌套饱和函数形式,证明了目标角速度的全局有界性质,从而可以获得姿态子系统相对于制导子系统的分离性质.%A control method is investigated for lunar lander' s final descent phase, at about 100m to 30m altitude above the surface of the moon. A simple guidance law is proposed and it is proved rigorously that the combined guidance and attitude control system is almost globally asymptotically stable. The main contributions of the study are that based on the form of nested saturation function, the simple guidance law can not only guarantee the boundness of the main thrust force and avoid the singularity in the attitude control, but are simpler compared with existing literature and are flexible in adjusting the maximum permissible inclination angle of the lander; thanks to the guidance law in the form of nested saturation function, the desired angular velocity is proven to be globally bounded, and a separation property between the guidance and the attitude subsystems is also obtained.

  12. PROFESSIONAL GUIDANCE: EXPERIENCE REPORT

    Directory of Open Access Journals (Sweden)

    Fabiana Pinto de Almeida Bizarria

    2014-05-01

    Full Text Available This article presents an account of a career guidance with a group of five teenagers ( 16 and 19 , students of pre-university preparatory course offered by a public university in the state of Ceará . The work group dynamics was from a privileged form of performance by allowing a greater enrichment of the discussions , considering the heterogeneity and diversity of the group . To address relevant issues in career guidance based on the theory Socio-Historical , a roadmap of action process was constructed from three axes . Each axis has worked in two sessions that match a date. The first axis called " meaning of choice," worked on thematic choice process . With regard to the axis " World of Work " was discussed idealizations and representations about the professions , the labor market and the vestibular / ESMS . Emotional links with the professions , skills and ideas on skills and information professions : Finally , the " self " axis, which contains the themes was developed .

  13. (1+1) EA on Generalized Dynamic OneMax

    DEFF Research Database (Denmark)

    Kötzing, Timo; Lissovoi, Andrei; Witt, Carsten

    2015-01-01

    Evolutionary algorithms (EAs) perform well in settings involving uncertainty, including settings with stochastic or dynamic fitness functions. In this paper, we analyze the (1+1) EA on dynamically changing OneMax, as introduced by Droste (2003). We re-prove the known results on first hitting time....... We get tight bounds both for the case of bit strings, as well as for the case of more than two values per position. Surprisingly, in the latter setting, the expected quality of the search point maintained by the (1+1) EA does not depend on the number of values per dimension....

  14. Optimal terminal guidance for exoatmospheric interception

    Directory of Open Access Journals (Sweden)

    Yu Wenbin

    2016-08-01

    Full Text Available In this study, two optimal terminal guidance (OTG laws, one of which takes into account the final velocity vector constraint, are developed for exoatmospheric interception using optimal control theory. In exoatmospheric interception, because the proposed guidance laws give full consideration to the effect of gravity, they consume much less fuel than the traditional guidance laws while requiring a light computational load. In the development of the guidance laws, a unified optimal guidance problem is put forward, where the final velocity vector constraint can be considered or neglected by properly adjusting a parameter in the cost function. To make this problem analytically solvable, a linear model is used to approximate the gravity difference, the difference of the gravitational accelerations of the target and interceptor. Additionally, an example is provided to show that some achievements of this study can be used to significantly improve the fuel efficiency of the pulsed guidance employed by the interceptor whose divert thrust level is fixed.

  15. Optimal terminal guidance for exoatmospheric interception

    Institute of Scientific and Technical Information of China (English)

    Yu Wenbin; Chen Wanchun; Yang Liang; Liu Xiaoming; Zhou Hao

    2016-01-01

    In this study, two optimal terminal guidance (OTG) laws, one of which takes into account the final velocity vector constraint, are developed for exoatmospheric interception using optimal control theory. In exoatmospheric interception, because the proposed guidance laws give full consideration to the effect of gravity, they consume much less fuel than the traditional guidance laws while requiring a light computational load. In the development of the guidance laws, a unified optimal guidance problem is put forward, where the final velocity vector constraint can be consid-ered or neglected by properly adjusting a parameter in the cost function. To make this problem ana-lytically solvable, a linear model is used to approximate the gravity difference, the difference of the gravitational accelerations of the target and interceptor. Additionally, an example is provided to show that some achievements of this study can be used to significantly improve the fuel efficiency of the pulsed guidance employed by the interceptor whose divert thrust level is fixed.

  16. Noise properties and cascadability of SOA-EA regenerators

    DEFF Research Database (Denmark)

    Öhman, Filip; Bischoff, Svend; Tromborg, Bjarne;

    2002-01-01

    We suggest and analyse a new device containing concatenated pairs of semiconductor optical amplifiers (SOAs) and electroabsorption modulators (EAs). The device has regenerative properties and improves the cascadability of optical fibre links....

  17. Severo-Vostoku ot EAS perepadajet malo / Jekaterina Guzhvina

    Index Scriptorium Estoniae

    Guzhvina, Jekaterina

    2007-01-01

    Mitmel turismiga tegeleval Ida-Viru ettevõtjal polnud piisavalt infot Ettevõtluse Arendamise Sihtasutuse interneti-projeti "Puhka Eestis" võimaluste kohta. EAS leiab, et ettevõtjad peaksid ise aktiivsemad olema

  18. 32 CFR 651.33 - Actions normally requiring an EA.

    Science.gov (United States)

    2010-07-01

    ... wildlife habitat, or wild and scenic rivers. (f) Actions proposed during the life cycle of a weapon system... normally requiring an EA during the life cycle include, but are not limited to, testing,...

  19. QUEST: wide angle Cherenkov light measurements at EAS-TOP

    Science.gov (United States)

    EAS-Top Collaboration; Korosteleva, E. E.; Kuzmichev, L. A.; Prosin, V. V.; Lubsandorzhiev, B. K.

    Wide angle Cherenkov light detectors based upon the QUASAR-370 photo-multipliers have been installed on five Cherenkov telescopes of the EAS-TOP array to study the energy spectrum and composition of primary cosmic rays around the knee . The energy threshold of quasars array was close to that of EAS-TOP electromagnetic detectors array. The first results of joint analysis of Cherenkov and electromagnetic data together with the adequate CORSIKA simulation results are discussed.

  20. Perceived Impact of Guidance and Counseling Services on the Development of Entrepreneurial Skills for Sustainable Livelihood among Students

    Science.gov (United States)

    Chinedum, Ubah Anthony; Onwuasoanya, Paul; Eze, Justina

    2012-01-01

    This paper focused on finding out the opinions of three categories of educators viz.: EA (education administrators), GC (guidance counselors), and CT (classroom teachers) on the impact of guidance and counselling services in entrepreneurship development among secondary school students. Three research questions were drawn to ascertain the opinions…

  1. 77 FR 61417 - Guidance for Industry on Acute Bacterial Sinusitis: Developing Drugs for Treatment; Availability

    Science.gov (United States)

    2012-10-09

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry on Acute Bacterial Sinusitis... entitled ``Acute Bacterial Sinusitis: Developing Drugs for Treatment.'' This guidance addresses FDA's... an indication for the treatment of acute bacterial sinusitis (ABS). This guidance finalizes the...

  2. Vasorelaxation Effect of Estrone Derivate EA204 in Rabbit Aorta

    Directory of Open Access Journals (Sweden)

    Juan Li

    2016-01-01

    Full Text Available Estrogen and its derivatives exert vascular protective effects, but the underlying mechanisms remain to be studied fully. Objective. To investigate the vasorelaxation effect and related mechanisms of an estrone derivate EA204[3-(2-piperidin-1-yl-ethoxy-estra-1, 3, 5 (10-trien-17-one] on isolated arterial preparation from rabbit thoracic aorta. Methods. Aortic rings from rabbit thoracic aorta were prepared and held in small organ bath filled with Krebs solution; tension change was recorded by a multichannel physiological signal collection and handling system. Results. EA204 (10−5 to 10−3 M induced a concentration-dependent relaxation of aortic rings with endothelium and without endothelium. In denuded arterial preparations, EA204 had a potent relaxing effect on isolated arterial preparations contracted with phenylephrine, norepinephrine, and high-K+ solution or BaCl2. Mechanism study indicates that EA204 relaxes aortic rings by inhibiting Ca2+ channels (both receptor-operating Ca2+ channels and the voltage-dependent Ca2+ channels were involved to decrease extracellular Ca2+ influx and intracellular Ca2+ release. EA204 is different from verapamil, which is a noncompetitive inhibitor of Ca2+ channels. In addition, K+ channels opening may contribute to this vasorelaxation effect. Conclusion. EA204 had a potent endothelium-independent relaxing effect on isolated arterial preparation by inhibiting Ca2+ channels and opening K+ channels. The results suggest that EA204 is a potential compound for treatment of cardiovascular diseases in postmenopausal women.

  3. Launch flexibility using NLP guidance and remote wind sensing

    Science.gov (United States)

    Cramer, Evin J.; Bradt, Jerre E.; Hardtla, John W.

    1990-01-01

    This paper examines the use of lidar wind measurements in the implementation of a guidance strategy for a nonlinear programming (NLP) launch guidance algorithm. The NLP algorithm uses B-spline command function representation for flexibility in the design of the guidance steering commands. Using this algorithm, the guidance system solves a two-point boundary value problem at each guidance update. The specification of different boundary value problems at each guidance update provides flexibility that can be used in the design of the guidance strategy. The algorithm can use lidar wind measurements for on pad guidance retargeting and for load limiting guidance steering commands. Examples presented in the paper use simulated wind updates to correct wind induced final orbit errors and to adjust the guidance steering commands to limit the product of the dynamic pressure and angle-of-attack for launch vehicle load alleviation.

  4. The Tunka-133 EAS Cherenkov light array: Status of 2011

    Energy Technology Data Exchange (ETDEWEB)

    Berezhnev, S.F. [Skobeltsyn Institute of Nuclear Physics MSU, Moscow (Russian Federation); Besson, D. [Department of Physics and Astronomy, University of Kansas (United States); Budnev, N.M. [Institute of Applied Physics ISU, Irkutsk (Russian Federation); Chiavassa, A. [Dipartimento di Fisica Generale, Universiteta di Torino, Torino (Italy); INFN, Torino (Italy); Chvalaev, O.A.; Gress, O.A.; Dyachok, A.N. [Institute of Applied Physics ISU, Irkutsk (Russian Federation); Epimakhov, S.N. [Skobeltsyn Institute of Nuclear Physics MSU, Moscow (Russian Federation); Haungs, A. [Karlsruhe Institute of Technology, Institut fuer Kernphysik, Karlsruhe (Germany); Karpov, N.I.; Kalmykov, N.N. [Skobeltsyn Institute of Nuclear Physics MSU, Moscow (Russian Federation); Konstantinov, E.N.; Korobchenko, A.V. [Institute of Applied Physics ISU, Irkutsk (Russian Federation); Korosteleva, E.E.; Kozhin, V.A. [Skobeltsyn Institute of Nuclear Physics MSU, Moscow (Russian Federation); Kuzmichev, L.A., E-mail: kuz@dec1.sinp.msu.ru [Skobeltsyn Institute of Nuclear Physics MSU, Moscow (Russian Federation); Lubsandorzhiev, B.K.; Lubsandorzhiev, N.B. [Institute for Nuclear Research of RAS, Moscow (Russian Federation); Mirgazov, R.R. [Institute of Applied Physics ISU, Irkutsk (Russian Federation); Panasyuk, M.I. [Skobeltsyn Institute of Nuclear Physics MSU, Moscow (Russian Federation); and others

    2012-11-11

    A new EAS Cherenkov light array, Tunka-133, with {approx}1km{sup 2} geometrical area has been installed at the Tunka Valley (50 km from Lake Baikal) in 2009. The array permits a detailed study of cosmic ray energy spectrum and mass composition in the energy range 10{sup 16}-10{sup 18} eV with a uniform method. We describe the array construction, DAQ and methods of the array calibration. The method of energy reconstruction and absolute calibration of measurements are discussed. The analysis of spatial and time structure of EAS Cherenkov light allows to estimate the depth of the EAS maximum X{sub max}. The results on the all particles energy spectrum and the mean depth of the EAS maximum X{sub max} vs. primary energy derived from the data of two winter seasons (2009-2011) are presented. Preliminary results of joint operation of the Cherenkov array with antennas for the detection of EAS radio signals are shown. Plans for future upgrades - deployment of remote clusters, radioantennas and a scintillator detector network and a prototype of the HiSCORE gamma-telescope - are discussed.

  5. Fluctuations in the temporal dispersion of muons in EAS

    Energy Technology Data Exchange (ETDEWEB)

    Collis, V.S.

    1987-01-01

    This thesis is concerned with measured fluctuations in the temporal dispersion of muons within extensive air showers (EAS), initiated by primaries of energy, 10/sup 17/ to 10/sup 18/ eV, as deduced from the rise-time measurements made on the signals from the Nottingham muon fast-timing recording systems, operated within the Haverah Park EAS array. The study of muon rise times provides a unique instrument in the analysis of the first stages in the development of the nuclear cascade in EAS, and therefore is important in establishing constraints on the mass composition of the primary cosmic rays. EAS detected by two 5 m/sup 2/ co-located muon detectors have their muon risetimes characterized here by T/sub 70/, the time elapsed between the 10% level and the 70% level of the fully integrated muon signal from scintillators. It is established that approx.6.5% of the muon pulse profiles display structure and it is proposed that these features are not due to large-scale EAS phenomena. The two-fold T/sub 70/ measurements enable the fluctuation width around T/sub 70/, associated with differences in nuclear cascade development, to be separated and measured, from which the corresponding fluctuation width in depth of maximum electron cascade development is calculated.

  6. 47 CFR 11.52 - EAS code and Attention Signal Monitoring requirements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false EAS code and Attention Signal Monitoring... SYSTEM (EAS) Emergency Operations § 11.52 EAS code and Attention Signal Monitoring requirements. (a) EAS Participants must be capable of receiving the Attention Signal required by § 11.32(a)(9) and emergency...

  7. 47 CFR 11.51 - EAS code and Attention Signal Transmission requirements.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false EAS code and Attention Signal Transmission... SYSTEM (EAS) Emergency Operations § 11.51 EAS code and Attention Signal Transmission requirements. (a... messages and required tests by sending the EAS header codes, Attention Signal, emergency message and End...

  8. Extension of Cherenkov Light LDF Approximation for Yakutsk EAS Array

    Directory of Open Access Journals (Sweden)

    A. A. Al-Rubaiee

    2014-01-01

    Full Text Available The simulation of the Cherenkov light lateral distribution function (LDF in extensive air showers (EAS was performed using CORSIKA code for configuration of Yakutsk EAS array at high energy range for different primary particles (p, Fe, and O2 and different zenith angles. Depending on Breit-Wigner function a parameterization of Cherenkov light LDF was reconstructed on the basis of this simulation as a function of primary energy. A comparison of the calculated Cherenkov light LDF with that measured on the Yakutsk EAS array gives the possibility of identification of the particle initiating the shower and determination of its energy in the knee region of the cosmic ray spectrum. The extrapolation of approximated Cherenkov light LDF for high energies was obtained for primary proton and iron nuclei.

  9. 2 CFR 182.40 - How is the guidance maintained?

    Science.gov (United States)

    2010-01-01

    ... AND AGREEMENTS Reserved GOVERNMENTWIDE REQUIREMENTS FOR DRUG-FREE WORKPLACE (FINANCIAL ASSISTANCE) § 182.40 How is the guidance maintained? The OMB publishes proposed changes to the guidance in the... groups, and then issues any changes to the guidance in final form. ...

  10. 77 FR 71019 - Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-04; Guidance on...

    Science.gov (United States)

    2012-11-28

    ... COMMISSION Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-04; Guidance on...: Nuclear Regulatory Commission. ACTION: Japan Lessons-Learned Project Directorate Interim Staff Guidance issuance. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is issuing the Final Japan...

  11. Collimation of energetic neutrinos and muons inside EAS cores

    Directory of Open Access Journals (Sweden)

    Cherif Talai Mohammed

    2013-06-01

    Full Text Available High-energy muon and neutrino components are simulated inside cores of EAS generated by primary protons and heavy nuclei of energies 1014-1020 eV. The collimation of muons and neutrinos inside the core is compared with present penetrating beams generated by accelerators.

  12. Properties of tangential and radial angles of muons in EAS

    OpenAIRE

    Zabierowski, J.; Daumiller, K.; Doll, P.

    2002-01-01

    Tangential and radial angles of muons in EAS, a useful concept in investigation of the muon production height, can be used also for the investigation of the muon momenta. A parameter zeta, being a combination of tangential and radial angles, is introduced and its possible applications in investigation of muons in showers are presented.

  13. (1+1) EA on Generalized Dynamic OneMax

    DEFF Research Database (Denmark)

    Kötzing, Timo; Lissovoi, Andrei; Witt, Carsten

    2015-01-01

    using the modern tool of drift analysis. We extend these results to search spaces which allow for more than two values per dimension. Furthermore, we make an anytime analysis as suggested by Jansen and Zarges (2014), analyzing how closely the (1+1) EA can track the dynamically moving optimum over time...

  14. 7 CFR 1794.23 - Proposals normally requiring an EA.

    Science.gov (United States)

    2010-01-01

    ... boundaries. (12) Installing a heat recovery steam generator and steam turbine with a rating of more than 200... classification are: (1) Construction of fuel cell, combustion turbine, combined cycle, or diesel generating... be covered in the EA; (2) Construction of fuel cell, combustion turbine, combined cycle, or...

  15. On guidance and volatility

    NARCIS (Netherlands)

    Billings, M.B.; Jennings, R.; Lev, B.

    2013-01-01

    Survey evidence suggests that managers voluntarily disclose information, particularly earnings guidance, with an aim toward dampening share price volatility. Yet, consultants and influential institutions advise against providing guidance — citing fears of litigation and market penalties associated w

  16. Graphic Turbulence Guidance

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Forecast turbulence hazards identified by the Graphical Turbulence Guidance algorithm. The Graphical Turbulence Guidance product depicts mid-level and upper-level...

  17. Graphical Turbulence Guidance - Composite

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Forecast turbulence hazards identified by the Graphical Turbulence Guidance algorithm. The Graphical Turbulence Guidance product depicts mid-level and upper-level...

  18. 78 FR 12760 - Guidance for Industry on Labeling for Human Prescription Drug and Biological Products...

    Science.gov (United States)

    2013-02-25

    ... January 24, 2006 (71 FR 3998), FDA announced the availability of final guidances on the content and format... of March 23, 2010 (75 FR 13766), FDA announced the availability of final guidance on the content and..., 2011 (76 FR 63303), FDA announced the availability of final guidance on the content and format of the...

  19. Autonomous gliding entry guidance with

    Directory of Open Access Journals (Sweden)

    Guo Jie

    2015-10-01

    Full Text Available This paper presents a novel three-dimensional autonomous entry guidance for relatively high lift-to-drag ratio vehicles satisfying geographic constraints and other path constraints. The guidance is composed of onboard trajectory planning and robust trajectory tracking. For trajectory planning, a longitudinal sub-planner is introduced to generate a feasible drag-versus-energy profile by using the interpolation between upper boundary and lower boundary of entry corridor to get the desired trajectory length. The associated magnitude of the bank angle can be specified by drag profile, while the sign of bank angle is determined by lateral sub-planner. Two-reverse mode is utilized to satisfy waypoint constraints and dynamic heading error corridor is utilized to satisfy no-fly zone constraints. The longitudinal and lateral sub-planners are iteratively employed until all of the path constraints are satisfied. For trajectory tracking, a novel tracking law based on the active disturbance rejection control is introduced. Finally, adaptability tests and Monte Carlo simulations of the entry guidance approach are performed. Results show that the proposed entry guidance approach can adapt to different entry missions and is able to make the vehicle reach the prescribed target point precisely in spite of geographic constraints.

  20. Ad memoriam E.A. Begovatov (1937–2015

    Directory of Open Access Journals (Sweden)

    Anna F. Kochkina

    2015-12-01

    Full Text Available Evgeniy A. Begovatov obituary shows his significant contribution to the development of methods of mathematical statistics in relation to archaeological and archaeo-zoological materials of the Volga and cis-Urals areas. E.A. Begovatov is known also as skilled numismatist and discoverer of many sites, such as the burial grounds of Tenishevo (Aeneolithic Age, Murzikha 2 (Early Metal Epokh and others.

  1. Ad memoriam E.A. Begovatov (1937–2015

    Directory of Open Access Journals (Sweden)

    Anna F. Kochkina

    2016-12-01

    Full Text Available Evgeniy A. Begovatov obituary shows his significant contribution to the development of methods of mathematical statistics in relation to archaeological and archaeo-zoological materials of the Volga and cis-Urals areas. E.A. Begovatov is known also as skilled numismatist and discoverer of many sites, such as the burial grounds of Tenishevo (Aeneolithic Age, Murzikha 2 (Early Metal Epokh and others.

  2. Equivalent reliability polynomials modeling EAS and their geometries

    Directory of Open Access Journals (Sweden)

    Hassan Zahir Abdul Haddi

    2015-07-01

    Full Text Available In this paper we shall introduce two equivalent techniques in order to evaluate reliability analysis of electrical aircrafts systems (EAS: (i graph theory technique, and (ii simplifying diffeomorphism technique. Geometric modeling of reliability models is based on algebraic hypersurfaces, whose intrinsic properties are able to select those models which are relevant for applications. The basic idea is to cover the reliability hypersurfaces by exponentially decay curves. Most of the calculations made in this paper have used Maple and Matlab software.

  3. The array for investigations of EAS neutron component

    Directory of Open Access Journals (Sweden)

    Gromushkin D.M.

    2017-01-01

    Full Text Available The neutron component of EAS has not been practically studied for many years. Creation of the neutron detector arrays PRISMA-32 and PRISMA-YBJ demonstrated the effectiveness of such investigations. It is important to underline that recording the EAS neutron component is carried out over the whole array area. Development of a new larger scale neutron detector array (URAN in MEPhI will continue these studies. During the construction of the URAN array, a new design of en-detectors based on the scintillator with natural boron and new electronics was developed. The use of new electronics with a switchable sampling rate allows one to reach EAS fast timing accuracy up to 10 ns. The en-detectors of the URAN are located on the roofs of the buildings. The sensitive area of each detector is 0.36 m2, while the array's starting area is ∼ 103 m2. Total number of the initial array detectors is 72. They are subdivided into 6 independent clusters each of 12 en-detectors, connected with the central data acquisition station.

  4. The array for investigations of EAS neutron component

    Science.gov (United States)

    Gromushkin, D. M.; Ampilogov, N. V.; Barbashina, N. S.; Bogdanov, F. A.; Kokoulin, R. P.; Ovchinnikov, V. V.; Petrukhin, A. A.; Shulzhenko, I. A.; Stenkin, Yu. V.; Yashin, I. I.; Yurin, K. O.

    2017-06-01

    The neutron component of EAS has not been practically studied for many years. Creation of the neutron detector arrays PRISMA-32 and PRISMA-YBJ demonstrated the effectiveness of such investigations. It is important to underline that recording the EAS neutron component is carried out over the whole array area. Development of a new larger scale neutron detector array (URAN) in MEPhI will continue these studies. During the construction of the URAN array, a new design of en-detectors based on the scintillator with natural boron and new electronics was developed. The use of new electronics with a switchable sampling rate allows one to reach EAS fast timing accuracy up to 10 ns. The en-detectors of the URAN are located on the roofs of the buildings. The sensitive area of each detector is 0.36 m2, while the array's starting area is ˜ 103 m2. Total number of the initial array detectors is 72. They are subdivided into 6 independent clusters each of 12 en-detectors, connected with the central data acquisition station.

  5. A Low-redshift Sample of E+A Galaxies

    Science.gov (United States)

    Walker, K. M.; Bergmann, M. P.; Turner, J.

    2004-12-01

    We present the results of a low-redshift survey for E+A galaxies. These galaxies are spectroscopically classified as having strong Balmer and metallic absorption with the absence of any emission. The absorption lines indicate an abundance of A-type stars as well as an old stellar population, while the absence of emission, especially {O ii}, denotes the lack of current star formation. Essential in determining the evolution of early-type galaxies, a low-redshift sample will allow easier morphology observations and further spectroscopic study. Fourteen low-redshift E+A galaxies were found using the Sloan Digital Sky Survey Data Release One following similar criteria as the H-delta strong survey of Goto (2003), except that only galaxies with a redshift lower than z=0.05 were selected. Two of these E+A galaxies were observed with the Cerro Tololo Inter-American Observatory 1.5-m telescope and confirmed to have no emission anywhere along the longslit, including outside the 3" region sampled by the SDSS fibers. This work was supported by the NSF through the CTIO REU program.

  6. 76 FR 49772 - Guidance for Industry: Bar Code Label Requirements-Questions and Answers; Availability

    Science.gov (United States)

    2011-08-11

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry: Bar Code Label Requirements... Industry: Bar Code Label Requirements--Questions and Answers'' dated August 2011. The guidance announced in... finalizes the draft guidance entitled ``Guidance for Industry: Bar Code Label Requirements--Questions and...

  7. 77 FR 60126 - Guidance for Industry on Acute Bacterial Otitis Media: Developing Drugs for Treatment; Availability

    Science.gov (United States)

    2012-10-02

    ...; Formerly 2008N-0004] Guidance for Industry on Acute Bacterial Otitis Media: Developing Drugs for Treatment... Administration (FDA) is announcing the availability of a guidance for industry entitled ``Acute Bacterial Otitis... treatment of acute bacterial otitis media (ABOM). This guidance finalizes the revised draft guidance of the...

  8. 76 FR 55390 - Guidance on Exculpatory Language in Informed Consent, Draft

    Science.gov (United States)

    2011-09-07

    ... HUMAN SERVICES Guidance on Exculpatory Language in Informed Consent, Draft AGENCY: Office for Human... the availability of a draft guidance entitled, ``Guidance on Exculpatory Language in Informed Consent.'' The draft guidance, when finalized, will represent OHRP's and FDA's current thinking on this topic...

  9. 75 FR 35492 - Guidance for Industry on Lupus Nephritis Caused By Systemic Lupus Erythematosus-Developing...

    Science.gov (United States)

    2010-06-22

    ... availability of a guidance for industry entitled ``Lupus Nephritis Caused By Systemic Lupus Erythematosus... nephritis (LN) caused by systemic lupus erythematosus (SLE). This guidance finalizes the parts of the draft guidance entitled ``Systemic Lupus Erythematosus--Developing Drugs for Treatment'' (the draft guidance...

  10. 77 FR 1676 - EasTrans, LLC; Notice Granting Extension of Time

    Science.gov (United States)

    2012-01-11

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission EasTrans, LLC; Notice Granting Extension of Time On December 16, 2011, Eas... an extension of time for EasTrans to file its section 284.123 rate petition is granted to...

  11. 78 FR 46295 - Special Conditions: Eclipse, EA500, Certification of Autothrottle Functions Under Part 23

    Science.gov (United States)

    2013-07-31

    ... Federal Aviation Administration 14 CFR Part 23 Special Conditions: Eclipse, EA500, Certification of... proposed special conditions. SUMMARY: This action proposes special conditions for the Eclipse EA500.... The Eclipse Model EA500 was certificated under part 23 by the FAA on September 30, 2006...

  12. Study of the shower maximum depth by the method of detection of the EAS Cerenkov light pulse shape

    Science.gov (United States)

    Aliev, N.; Alimov, T.; Kakhkharov, M.; Khakimov, N.; Makhmudov, B. M.; Rakhimova, N.; Tashpulatov, R.; Khristiansen, G. B.; Prosin, V. V.; Zhukov, V. Y.

    1985-01-01

    The results of processing the data on the shape of the EAS Cerenkov light pulses recorded by the extensive air showers (EAS) array are presented. The pulse FWHM is used to find the mean depth of EAS maximum.

  13. Career guidance in communities

    DEFF Research Database (Denmark)

    Thomsen, Rie

    The aim of this paper is to inspire practitioners and professionals to leave their offices to bring career guidance into communities that might not identify with career guidance in the first instance. By making the effort to engage with communities, practitioners may bring about a critical change...

  14. Corporate information management guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    At the request of the Department of Energy`s (DOE) Information Management (IM) Council, IM representatives from nearly all Headquarters (HQ) organizations have been meeting over the past year as the Corporate Guidance Group (CGG) to develop useful and sound corporate information management (IM) guidance. The ability of the Department`s IM community to develop such unified guidance continues to be critical to the success of future Departmental IM planning processes and the establishment of a well-coordinated IM environment between Headquarters and field organizations. This report, with 26 specific corporate IM guidance items documented and unanimously agreed to, as well as 12 items recommended for further development and 3 items deferred for future consideration, represents a highly successful effort by the IM community. The effort has proven that the diverse DOE organizations can put aside individual preferences and work together towards a common and mutually beneficial goal. In examining most areas and issues associated with information management in the Department, they have developed specific, far-reaching, and useful guidance. The IM representatives recommend that the documented guidance items provided in this report and approved by the DOE IM Council be followed by all IM organizations. The representatives also strongly recommend that the guidance process developed by the CGG be the single process for developing corporate IM guidance.

  15. Shuttle entry guidance

    Science.gov (United States)

    Harpold, J. C.; Graves, C. A., Jr.

    1978-01-01

    This paper describes the design of the entry guidance for the Space Shuttle Orbiter. This guidance provides the steering commands for trajectory control from initial penetration of the earth's atmosphere until the terminal area guidance is activated at an earth-relative speed of 2500 fps. At this point, the Orbiter is at a distance of about 50 nmi from the runway threshold, and at an altitude of about 80,000 ft. The entry guidance design is based on an analytic solution of the equations of motion defining the drag acceleration profile that meets the terminal criteria of the entry flight while maintaining the flight within systems and operational constraints. Guidance commands, which are based on a control law that ensures damping of oscillatory type trajectory motion, are computed to steer the Orbiter to this drag acceleration profile.

  16. Shuttle entry guidance revisited

    Science.gov (United States)

    Mease, Kenneth D.; Kremer, Jean-Paul

    1992-08-01

    The Shuttle entry guidance concept is reviewed which is aimed at tracking a reference drag trajectory that leads to the specified range and velocity for the initiation of the terminal energy management phase. An approximate method of constructing the domain of attraction is proposed, and its validity is ascertained by simulation. An alternative guidance law yielding global exponential tracking in the absence of control saturation is derived using a feedback linearization method. It is noted that the alternative guidance law does not improve on the stability and performance of the current guidance law, for the operating domain and control capability of the Shuttle. It is suggested that the new guidance law with a larger operating domain and increased lift-to-drag capability would be superior.

  17. Shuttle entry guidance revisited

    Science.gov (United States)

    Mease, Kenneth D.; Kremer, Jean-Paul

    1992-01-01

    The Shuttle entry guidance concept is reviewed which is aimed at tracking a reference drag trajectory that leads to the specified range and velocity for the initiation of the terminal energy management phase. An approximate method of constructing the domain of attraction is proposed, and its validity is ascertained by simulation. An alternative guidance law yielding global exponential tracking in the absence of control saturation is derived using a feedback linearization method. It is noted that the alternative guidance law does not improve on the stability and performance of the current guidance law, for the operating domain and control capability of the Shuttle. It is suggested that the new guidance law with a larger operating domain and increased lift-to-drag capability would be superior.

  18. An Improved Model Facet Method to Support EA Alignment

    Directory of Open Access Journals (Sweden)

    Jonathan Pepin

    2016-12-01

    Full Text Available Information System evolution requires a well-structured Enterprise Architecture and its rigorous management. The alignment of the elements in the architecture according to various abstraction layers may contribute to the management but appropriate tools are needed. We propose improvements to the Facet technique and we develop accompanying tools to master the difficulties of the alignment of the models used to structure an Enterprise Architecture. This technique has been experimented on many real life cases to demonstrate the effectiveness of our EA alignment method. The tools are already integrated in the Eclipse EMF Facet project.

  19. EA-18G的测试与评估

    Institute of Scientific and Technical Information of China (English)

    杨曼; 王燕

    2013-01-01

    继2009年年初成功完成作战测试与评估后,EA-18G“咆哮者”机身及其系统的研发工作还在继续。这个过程被称作“后续测试与评估”(FOT&E),由美国海军航空系统司令部的VX-31“尘暴”(Dust Devils)和VX-23“咸狗”(Salty Dogs)空中测试与评估中队完成。

  20. Quality guidance and quality formation

    DEFF Research Database (Denmark)

    Poulsen, Carsten Stig; Juhl, Hans Jørn; Kristensen, Kai

    1996-01-01

    This paper presents an extension of the quality guidance model of Steenkamp and van Trijp that includes consumer quality formation processes. Quality expectations and quality experiences are seen as antecedents of perceived overall product quality conceptual model is applied using LISREL to a data...... set on Danish butter cookies. Five plausible models of the relation between expectation, experience and perceived product quality are estimated. Finally one model is selected on the basis of three criteria: chi-square, RMSEA and AIC: The results show a model where expectations are indirectly related...... to perceived quality through experience. Udgivelsesdato: APR...

  1. Quality guidance and quality formation

    DEFF Research Database (Denmark)

    Poulsen, Carsten Stig; Juhl, Hans Jørn; Kristensen, Kai

    1996-01-01

    This paper presents an extension of the quality guidance model of Steenkamp and van Trijp that includes consumer quality formation processes. Quality expectations and quality experiences are seen as antecedents of perceived overall product quality conceptual model is applied using LISREL to a data...... set on Danish butter cookies. Five plausible models of the relation between expectation, experience and perceived product quality are estimated. Finally one model is selected on the basis of three criteria: chi-square, RMSEA and AIC: The results show a model where expectations are indirectly related...... to perceived quality through experience. Udgivelsesdato: APR...

  2. Laser Guidance Analysis Facility

    Data.gov (United States)

    Federal Laboratory Consortium — This facility, which provides for real time, closed loop evaluation of semi-active laser guidance hardware, has and continues to be instrumental in the development...

  3. 76 FR 81513 - Guidance for Industry: Prevention of Salmonella

    Science.gov (United States)

    2011-12-28

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry: Prevention of Salmonella Enteritidis... availability of a guidance for industry entitled ``Prevention of Salmonella Enteritidis in Shell Eggs During... with certain provisions contained in FDA's final rule ``Prevention of Salmonella Enteritidis in...

  4. Hot deformation behavior of EA4T steel

    Institute of Scientific and Technical Information of China (English)

    Gang XU; Lina WANG; Shiqi LI; Le WANG

    2012-01-01

    The compressive deformation behavior of EA4T steel was investigated at temperatures ranging from 950 to 1150℃ and strain rates from 0.1 to 20 s-1 on Gleeble-1500 thermo-simulation machine.The work hardening rate versus stress curves were used to determine the characteristic points of flow curves.The application of constitutive equations to determine the hot working constants of this material was discussed.Furthermore,the effect of Zener-Hollomon parameter (Z) on the characteristic points of flow curves was studied using the power law relation.The deformation activation energy of this steel was determined as 309.5 kJ/mol.Some behaviors were compared to other steels.

  5. Modified EAS Tag Used as a Resistive Sensor Platform

    Directory of Open Access Journals (Sweden)

    Henrik Andersson

    2012-11-01

    Full Text Available In this article, a modified design of an RF Radio Frequency Electronic Article Surveillance (EAS tag, used as a sensor platform, is manufactured and characterized. EAS tags are passive devices consisting of a capacitor and coil, tuned to a resonance frequency readable by the detector equipment, in this case 8.2 MHz. They were originally used to detect whether merchandise was being moved through the detection gates at shop exits, in which case an alarm was triggered. If the capacitance is divided in two and a resistive sensor device inserted in between, the resonant Inductor-Capacitor (LC circuit becomes an Inductor-Capacitor-Capacitor-Resistor LCCR circuit and can be used as a sensor tag. A high sensor resistance means that one capacitor is decoupled, leading to one resonance frequency, while a low resistance will couple both capacitances into the circuit, resulting in a lower resonance frequency. Different types of resistive sensors exist that are able to detect properties such as pressure, moisture, light and temperature. The tag is manufactured in Aluminum foil on a polyetylentereftalat (PET substrate, resulting in a cost effective RF-platform for various resistive sensors. Two types of tags are designed and manufactured, one with parallel plate capacitors and the other with interdigital capacitors. To test the tags, a resistive tilt sensor is mounted and the tags are characterized using a network analyzer. It is shown that for high resistance, the tags have a resonance frequency of morethan 10 MHz while for low values the frequency approaches 8.2 MHz.

  6. Search for gamma-ray induced showers from the lateral distribution of electrons in EAS

    CERN Document Server

    Dey, R K

    2015-01-01

    Distinguishing $\\gamma$-ray and hadron initiated extensive air showers (EAS) based on lateral distribution of electrons has been studied by detailed Monte Carlo (MC) simulations. The possibility of using the local age parameter (LAP) of EAS for the gamma-hadron separation has been explored. It is found that separating $\\gamma$-ray and hadron induced EAS on the basis of LAP can be useful for surface detector experiments those have no reliable muon measurement facilities.

  7. Simultaneous and multiple EAS Events due to the Gerasimova-Zatsepin Effect with the LAAS Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Iyono, A. [Dept. of Fundamental Science, Okayama University of Science, Okayama 700-0005 (Japan); Matsumoto, H. [Graduate School of Informatics, Okayama University of Science, Okayama 700-0005 (Japan); Okei, K.; Tsuji, S. [Kawasaki Medical School, Kurashiki, Okayama 701-0192 (Japan); Ohara, S. [Nara University of Industry, Ikoma-gun, Nara 636-8503 (Japan); Ochi, N. [Yonago National College of Technology, Yonago, Tottori 683-8502 (Japan); Konishi, T. [Department of Physics, Kinki University, Higashi-Osaka, Osaka 577-8502 (Japan); Takahashi, N. [Department of Advanced Physics, Hirosaki University, Hirosaki, Aomori 036-8561 (Japan); Yamamoto, I. [Faculty of Engineering, Okayama University of Science, Okayama 700-0005 (Japan); Nakatsuka, T. [Okayama Shoka University, Okayama 700-8601 (Japan); Nakamura, T.; Ohmori, N. [Faculty of Science, Kochi University, Kochi 780-8520 (Japan); Saitoh, K. [Ashikaga Institute of Technology, Ashikaga 326-8558 (Japan)

    2009-12-15

    We have measured extensive air showers (EAS) with primary cosmic ray energies above PeV at multiple EAS observatories deployed in Japan since 1996. Each array has been located on the rooftops of buildings in the university campus, and has a GPS-disciplined 10 MHz oscillator to provide UTC time stamps for each EAS event with microsecond accuracies. We have carried out a search for simultaneous and parallel EAS events at multiple EAS sites, such as Gerasimova-Zatsepin events, by comparing the EAS arrival time stamp and directions between long baseline EAS arrays. We selected EAS pairs for which the time difference and angular distance were less than 15 deg. and 5 msec respectively and then examined the angular distances of these events from the solar and lunar directions. Consequently, we conclude that we do not find any excesses of these events in the solar direction so far, as expected in the theoretical prediction of GZ effects. We found deficiencies of EAS pairs in the lunar direction, but its deviation is not significant.

  8. Reliability and validity of the Euthanasia Attitude Scale (EAS) for Hong Kong medical doctors.

    Science.gov (United States)

    Tang, Wai-Kiu; Mak, Kwok-Kei; Kam, Philip Ming-Ho; Ho, Joanna Wing-Kiu; Chan, Denise Che-Ying; Suen, To-Lam; Lau, Michael Chak-Kwan; Cheng, Adrian Ka-Chun; Wan, Yuen-Ting; Wan, Ho-Yan; Hussain, Assad

    2010-08-01

    This study aimed to examine the reliability and validity of the Euthanasia Attitude Scale (EAS) in Hong Kong medical doctors. A total of 107 medical doctors (61.7% men) participated in a survey at clinical settings in 2008. The 21-item EAS was used to assess their attitudes toward euthanasia. The mean (standard deviation) and median of the EAS were 63.60 (60.31) and 63.00. Total EAS scores correlated well with ''Ethical Considerations,'' ''Practical Considerations,'' and ''Treasuring Life'' (Spearman rho =.37-.96, P Euthanasia Attitude Scale may be a reliable and valid measure for assessing the attitudes toward euthanasia in medical professionals.

  9. My view on occupation guidance

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    Occupation instruction needs to the support of theories,in the case of the occupation guidance theory is not very developed in our country,It has very important sense that absorbing and drawing lessons from the advanced occupation guidance theory,and targeting guidance to occupation guidance work,.

  10. Final Environmental Assessment (EA) for Replacement of the Wastewater Lift Station (Building 510)

    Science.gov (United States)

    2013-03-01

    approximately 432 square feet and contains two pumps, various valves , and electrical equipment necessary to pump wastewater from a lower to higher elevation... Butterfly Plant, or either of these species’ associated habitats. It is our understanding that this satisfies our responsibilities under Section ?(c) of

  11. Final Environmental Assessment (EA) for the Revitalization of Military Family Housing Keesler AFB, MS

    Science.gov (United States)

    2006-03-01

    to the following factors depending on the corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022...Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To...convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 Nox (tons/yr) = NOxE * DPYII/2000 PM10(tons/yr) = PM10E * DPYII/2000

  12. Guidance and dispersion studies of National Launch System ascent trajectories

    Science.gov (United States)

    Hanson, John M.; Shrader, M. W.; Chang, Hopen; Freeman, Scott E.

    1992-01-01

    The National Launch System (NLS) is a joint concept, between DoD and NASA, for building a family of new launch vehicles. Two of the many choices to be made are the trajectory shaping methods and the onboard guidance scheme. This paper presents results from some ongoing studies to address these issues. First, potential gains from new guidance concepts are listed. Next the paper gives a list of possible discriminators between different guidance schemes, lists a number of potential guidance schemes, and explains two in some detail. A reference scheme is tested to determine its performance versus the discriminators. Finally, results from some special studies using the reference guidance scheme are given, including the effects of closed-loop guidance initiation time, time of enforcement of sideslip, vehicle roll for engine out, time and location of an engine out, use of load relief control, and use of day of launch wind biasing.

  13. Guidance for UMTRA project surveillance and maintenance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1986-01-01

    The Guidance for UMTRA Project Surveillance and Maintenance describes the procedures that will be used to verify that Uranium Mill Tailings Remedial Action (UMTRA) Project disposal sites continue to function as designed. The approach of this guidance document is to identify surveillance requirements and maintenance procedures that will be used to comply with NRC license requirements. This document addresses five primary activities: Definition and characterization of final site conditions. Site inspections; Ground-water monitoring; Aerial photography; and Custodial maintenance and contingency repair. Final site conditions will be defined and characterized prior to the completion of remedial actions at a site. As-built drawings will be compiled, a final topographic survey will be performed, a vicinity map will be prepared, and ground and aerial photographs will be taken. Survey monuments, site markers, and signs will be established as will a network of monitoring wells.

  14. Searching saturation effects in inclusive and exclusive eA processes

    Directory of Open Access Journals (Sweden)

    Goncalves V. P.

    2016-01-01

    Full Text Available The searching of saturation effects in inclusive and exclusive eA collisions is reviewed. In particular, we present a comparison between the linear and non-linear predictions for the nuclear structure functions as well as for the Deep Virtual Compton Scattering and vector meson production in future eA colliders.

  15. 47 CFR 101.1317 - Competitive bidding procedures for mutually exclusive MAS EA applications.

    Science.gov (United States)

    2010-10-01

    ... exclusive MAS EA applications. 101.1317 Section 101.1317 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... License Requirements § 101.1317 Competitive bidding procedures for mutually exclusive MAS EA applications. Mutually exclusive initial applications for licenses in the portions of the MAS bands licensed on a...

  16. 47 CFR 73.4097 - EBS (now EAS) attention signals on automated programing systems.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 4 2010-10-01 2010-10-01 false EBS (now EAS) attention signals on automated programing systems. 73.4097 Section 73.4097 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... (now EAS) attention signals on automated programing systems. See Public Notice dated March 1, 1979....

  17. 36 CFR 1010.10 - Actions that normally require an EA.

    Science.gov (United States)

    2010-07-01

    ... an EA. 1010.10 Section 1010.10 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.10 Actions that normally require an EA. (a) General procedure. If a proposal or action is not one that normally requires an EIS, and does not qualify for a categorical exclusion under §...

  18. 36 CFR 1010.6 - Determination of requirement for EA or EIS.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Determination of requirement for EA or EIS. 1010.6 Section 1010.6 Parks, Forests, and Public Property PRESIDIO TRUST ENVIRONMENTAL QUALITY § 1010.6 Determination of requirement for EA or EIS. In deciding whether to require...

  19. MISCIBILITY, SOLUBILITY, VISCOSITY, AND DENSITY MEASUREMENTS FOR R-236EA WITH FOUR DIFFERENT EXXON LUBRICANTS

    Science.gov (United States)

    The report discusses miscibility, solubility, viscosity, and density data for the refrigerant hydrofluorocarbon (HFC)-236ea (or R-236ea) and four lubricants supplied by Exxon Corporation. Such data are needed to determine the suitability of refrigerant/lubricant combinations for ...

  20. 47 CFR 11.55 - EAS operation during a State or Local Area emergency.

    Science.gov (United States)

    2010-10-01

    .... At that time begin transmitting the common emergency message received from the above sources. (6...-level and geographically targeted EAS messages, as aggregated and delivered by the state governor or his... providers shall pass through all EAS messages aired on local television broadcast stations carried by...

  1. 78 FR 57470 - Special Conditions: Eclipse, EA500, Certification of Autothrottle Functions

    Science.gov (United States)

    2013-09-19

    ... Federal Aviation Administration 14 CFR Part 23 Special Conditions: Eclipse, EA500, Certification of.... SUMMARY: These special conditions are issued for the Eclipse EA500 airplane. This airplane as modified by... systems installed and under 14 CFR part 135 with additional equipment installed. The Eclipse Model...

  2. MODELING AND DESIGN STUDY USING HFC-236EA AS AN ALTERNATIVE REFRIGERANT IN A CENTRIFUGAL COMPRESSOR

    Science.gov (United States)

    The report gives results of an investigation of the operation of a centrifugal compressor--part of a chlorofluorocarbon (CFC)-114 chiller installation--with the new refrigerant hydrofluorocarbon (HFC)-236ea, a proposed alternative to CFC-114. A large set of CFC-236ea operating da...

  3. REDES TECNOLÓGICAS APLICADAS EM EaD

    Directory of Open Access Journals (Sweden)

    Suélly Lima dos Santos

    2011-08-01

    Full Text Available Com o advento da internet e o aparecimento das novas tecnologias educacionais, conjunto de informações e comunicações (telefone, internet, rádio, vídeo, computador e televisão, ultrapassaram as fronteiras das quatro paredes da sala de aula, surgindo ambientes virtuais direcionadas à ampliação da participação dos serviços públicos relacionados ao ensino. À educação e à formação técnica e profissional permitiu-se o aumento da interatividade através da tecnologia, promovendo maneiras de acesso ao aluno utilizando computadores e/ou dispositivos móveis que viabiliza a Educação à Distância (EaD. Devido o grande crescimento do ensino à distância, as instituições já utilizam redes de dados para ampliar o acesso de aprendizagem. Com este espantoso aumento das redes, e da acelerada transmissão de informações aprender como elas funcionam é muito importante, além do mais usando a própria tecnologia para este fim. Como conclusão deste trabalho as mudanças relâmpadas da grande disponibilidade de dados no ambiente virtual é de enorme valia para o processo ensino-aprendizado.

  4. 77 FR 24722 - Draft Guidance for Industry: Safety of Nanomaterials in Cosmetic Products; Availability

    Science.gov (United States)

    2012-04-25

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry: Safety of Nanomaterials in... ``Guidance for Industry: Safety of Nanomaterials in Cosmetic Products.'' The draft guidance, when finalized, will represent FDA's current thinking on the safety assessment of nanomaterials in cosmetic...

  5. EA follow-up in the Ghanaian mining sector: Challenges and opportunities

    Energy Technology Data Exchange (ETDEWEB)

    Appiah-Opoku, Seth, E-mail: sappiah@bama.ua.edu [Geography Department, University of Alabama, 230 Farrah Hall, Tuscaloosa, AL 35487 (United States); Bryan, Hobson C. [Geography Department, University of Alabama, 330 Farrah Hall, Tuscaloosa, AL 35487 (United States)

    2013-07-15

    Environmental assessment (EA) follow-up provides a means for monitoring and evaluating the implementation of environmental impact studies. It is integral to the success or failure of a project or program. In spite of its importance, very little attention is given to the need for follow-up programs in most jurisdictions in Africa. Using a case study in the Ghanaian mining sector, this paper explores the challenges and opportunities within the country's EA process for an effective follow-up program. The paper is based on informal interviews, content analysis of relevant publications, official EA documents, and internet searches. The authors suggest a standard EA follow-up program to be formalized as an integral part of Ghana's environmental assessment policy. They also propose a follow-up process that harnesses existing opportunities within the country's EA system. This approach can be replicated in other African countries.

  6. [Labelling of nif-plasmid pEA9 from Enterobacter agglomerans 339].

    Science.gov (United States)

    Liu, Cheng-jun; Klingmüller, Walter

    2002-07-01

    The authors describe the in vivo labelling of the plasmid pEA9 in Enterobacter agglomerans 339 with a kanamycin resistance gene. For labelling purposes the donor plasmid pST5 was constructed. This plasmid contains the nif ENX region from pEA9,in which a kanamycin resistance gene is cloned.pST5 was transformed into E.a.339 and subsequently cured from the host. Curing was achieved with AP medium. Fourty strains that had lost pST5,but retained the kanamycin resistance, could be isolated. It showed that none of these clones contained co-integrates of pST5 and pEA9. This is evident that in all clones the kanamycin resistance gene was integrated into pEA9 by homologous recombination.

  7. Runtime analysis of the (1+1) EA on computing unique input output sequences

    DEFF Research Database (Denmark)

    Lehre, Per Kristian; Yao, Xin

    2010-01-01

    Computing unique input output (UIO) sequences is a fundamental and hard problem in conformance testing of finite state machines (FSM). Previous experimental research has shown that evolutionary algorithms (EAs) can be applied successfully to find UIOs for some FSMs. However, before EAs can...... are provably better than random search strategies. This paper presents rigorous theoretical and numerical analyses of the runtime of the (1 + 1) EA and random search on several selected instance classes of this problem. The theoretical analysis shows firstly, that there are instance classes where the EA...... in the theoretical analysis, and the variability of the runtime. The numerical results fit well with the theoretical results, even for small problem instance sizes. Together, these results provide a first theoretical characterisation of the potential and limitations of the (1 + 1) EA on the problem of computing UIOs....

  8. Vocational Guidance for Everyone

    Science.gov (United States)

    Holland, John L.

    1974-01-01

    Describes some of the current problems of vocational guidance, summarizes relevant knowledge and theory in the field, and offers some practical plans for a coordinated, theoretically compatible group of vocational programs, services, and experiences for a high school. (Author/JM)

  9. PIV Logon Configuration Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Glen Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-04

    This document details the configurations and enhancements implemented to support the usage of federal Personal Identity Verification (PIV) Card for logon on unclassified networks. The guidance is a reference implementation of the configurations and enhancements deployed at the Los Alamos National Laboratory (LANL) by Network and Infrastructure Engineering – Core Services (NIE-CS).

  10. Regulatory guidance document

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-05-01

    The Office of Civilian Radioactive Waste Management (OCRWM) Program Management System Manual requires preparation of the OCRWM Regulatory Guidance Document (RGD) that addresses licensing, environmental compliance, and safety and health compliance. The document provides: regulatory compliance policy; guidance to OCRWM organizational elements to ensure a consistent approach when complying with regulatory requirements; strategies to achieve policy objectives; organizational responsibilities for regulatory compliance; guidance with regard to Program compliance oversight; and guidance on the contents of a project-level Regulatory Compliance Plan. The scope of the RGD includes site suitability evaluation, licensing, environmental compliance, and safety and health compliance, in accordance with the direction provided by Section 4.6.3 of the PMS Manual. Site suitability evaluation and regulatory compliance during site characterization are significant activities, particularly with regard to the YW MSA. OCRWM`s evaluation of whether the Yucca Mountain site is suitable for repository development must precede its submittal of a license application to the Nuclear Regulatory Commission (NRC). Accordingly, site suitability evaluation is discussed in Chapter 4, and the general statements of policy regarding site suitability evaluation are discussed in Section 2.1. Although much of the data and analyses may initially be similar, the licensing process is discussed separately in Chapter 5. Environmental compliance is discussed in Chapter 6. Safety and Health compliance is discussed in Chapter 7.

  11. Career guidance on the move

    DEFF Research Database (Denmark)

    Thomsen, Rie

    2013-01-01

    This article is about how the notion of place can be used in an analysis of career guidance practices and their development. It is about how a focus on the context of career guidance can develop an awareness of the place where guidance is practiced and support the development of career guidance...... in new places. In this article I introduce an analytical perspective on place; I give the example of the guidance café a practice development that took place into serious consideration because it was an attempt to develop career guidance practice through relocating it....

  12. Energy Efficiency/Renewable Energy Programs in State Implementation Plans - Guidance Documents

    Science.gov (United States)

    final document that provides guidance to States and local areas on quantifying and including emission reductions from energy efficiency and renewable energy measures in State Implementation Plans (SIPS).

  13. 75 FR 42819 - Notice of Availability of a Final Environmental Assessment (Final EA) and a Finding of No...

    Science.gov (United States)

    2010-07-22

    ... easement that would also contain underground utility lines. The access road and radar site together... Surveillance Radar, Model 9, West Chicago, IL AGENCY: Federal Aviation Administration (FAA), DOT. ACTION... Impact (FONSI)/Record of Decision (ROD) for the Proposed ORD Airport Surveillance Radar, Model 9,...

  14. Advances in spacecraft atmospheric entry guidance

    Science.gov (United States)

    Benito Manrique, Joel

    acceleration guidance approach successfully used in missions like the Space Shuttle. Based on this approach, a new planner has been developed that is computationally fast and provides trajectories with both high final altitude and high control authority. A new tracking law based on nonlinear predictive control has been developed to track the reference trajectory. The new tracking law accounts for control saturation, which is a common feature of trajectories in the thin Martian atmosphere with a low lift vehicle. Finally, a final position guidance algorithm that aligns the vehicle's heading towards the target and provides altitude and range control, has been developed. The new guidance algorithm provides increased accuracy as well as higher final altitude compared to an entry guidance algorithm representative of the current capabilities.

  15. A Terminal Guidance Law Based on Motion Camouflage Strategy of Air-to-Ground Missiles

    Directory of Open Access Journals (Sweden)

    Chang-sheng Gao

    2016-01-01

    Full Text Available A guidance law for attacking ground target based on motion camouflage strategy is proposed in this paper. According to the relative position between missile and target, the dual second-order dynamics model is derived. The missile guidance condition is given by analyzing the characteristic of motion camouflage strategy. Then, the terminal guidance law is derived by using the relative motion of missile and target and the guidance condition. In the process of derivation, the three-dimensional guidance law could be designed in a two-dimensional plane and the difficulty of guidance law design is reduced. A two-dimensional guidance law for three-dimensional space is derived by bringing the estimation for target maneuver. Finally, simulation for the proposed guidance law is taken and compared with pure proportional navigation. The simulation results demonstrate that the proposed guidance law can be applied to air-to-ground missiles.

  16. Islamic Guidance for Drug Addiction

    Directory of Open Access Journals (Sweden)

    Agus Supriyanto

    2016-10-01

    Full Text Available Islamic Guidance is social rehabilitation program for Drug Addiction (resident. The goal of this research to know the Islamic guidance for resident at the Center for Rehabilitation of the National Narcotics Agency Lido Bogor. The methodology in this research is qualitative descriptive, with a sample two religious counselor. Can be concluded that Islamic guidance is implemented with the classical format, group format, and individual formats. The goal of the Islamic Guidance to develop religious mentally.

  17. Islamic Guidance for Drug Addiction

    OpenAIRE

    Agus Supriyanto

    2016-01-01

    Islamic Guidance is social rehabilitation program for Drug Addiction (resident). The goal of this research to know the Islamic guidance for resident at the Center for Rehabilitation of the National Narcotics Agency Lido Bogor. The methodology in this research is qualitative descriptive, with a sample two religious counselor. Can be concluded that Islamic guidance is implemented with the classical format, group format, and individual formats. The goal of the Islamic Guidance to develop religio...

  18. Relaxant effect of an estrone derivate EA303 on isolated colonic smooth muscle of rabbits

    Institute of Scientific and Technical Information of China (English)

    ZHU Lan; FU Shou-ting; CHEN Guo-liang; ZHOU Qian-qian

    2008-01-01

    Objective To study the relaxant effect mechanism of an estrone derivate EA303 on isolate colonic smooth muscle of rabbits. Methods Preparations of the isolated colonic smooth muscle of rabbits were prepared. The effect of EA303 on potassium channel, β receptor and prostaglandin were studied by observing the difference of relaxant dose-effect curves of EA303 on preparations pre-contracted with BaCl3, High K+ solution and Acetylcholine chloride (ACh) in the absence or presence incubation with glibenclamide (10 μM), propranolol (0.1 μM) and Indometacin (10 μM). Results The relaxant effect of EA303 on contraction caused by BaCl2 and High K+ solution were weakened by glibenclamide inhibiting the opening of K+ channel while the relaxant effect of that on contraction caused by ACh was strengthened, after adding propranolol inhabiting β receptor, EA303 attenuated the relaxant action on contraction caused by BaCl2. EA303 had some relaxant impact on contraction induced by High K+ solution after adding indometacin inhabiting the synthesis the prostaglandin (PG). Conclusions The relaxant effect of EA303 on isolated colonic smooth muscle of rabbits may be related with PG synthesis enzyme, potassium channel and β receptor.

  19. 78 FR 69691 - Draft Guidance for Industry on Product Name Placement, Size, and Prominence in Advertising and...

    Science.gov (United States)

    2013-11-20

    ..., and Prominence in Advertising and Promotional Labeling; Availability AGENCY: Food and Drug... Advertising and Promotional Labeling.'' When finalized, the draft guidance will replace the guidance of the... placement, size, prominence, and frequency in promotional labeling and advertising for prescription...

  20. Pollution Control Guidance for Geothermal Energy Development

    Energy Technology Data Exchange (ETDEWEB)

    Hartley, Robert P.

    1978-06-01

    This report summarizes the EPA regulatory approach toward geothermal energy development. The state of knowledge is described with respect to the constituents of geothermal effluents and emissions, including water, air, solid wastes, and noise. Pollutant effects are discussed. Pollution control technologies that may be applicable are described along with preliminary cost estimates for their application. Finally discharge and emission limitations are suggested that may serve as interim guidance for pollution control during early geothermal development.

  1. Determination of the EAS Attenuation Length from Data of the ANI Experiment

    CERN Document Server

    Chilingarian, A A; Kazarian, S; Hovsepyan, G G; Mamidjanyan, E A; Melkumyan, L G; Sokhoyan, S H

    2000-01-01

    Using the EAS size spectra measured with the MAKET ANI array on Mt. Aragats,Armenia (3200m a.s.l.) in the range of the shower size 10^5 - 10^7 fordifferent angles-of-incidence, the EAS attenuation length has been determinedapplying different analysis methods. The analysis is based on a data sample of2.5*10^6 events collected in the period of June, 97 - April, 99. The resultsare compared with results deduced from data of the EAS TOP and KASCADEexperiments.

  2. Extended High-Gain Observer for Mars Entry Guidance

    Directory of Open Access Journals (Sweden)

    Pingyuan Cui

    2013-02-01

    Full Text Available To deliver a Mars entry vehicle to the prescribed parachute deployment point, active entry guidance is essential. This paper addresses the problem of Mars atmospheric entry guidance through drag tracking method with extended high gain observer. First, an extended high gain observer combined with feedback linearization is applied in drag tracking for Mars entry longitudinal guidance.  The observer estimates the drag and drag rate for drag tracking, estimates the perturbation due to model uncertainty and disturbance, and compensate for the perturbation by canceling its estimate. Then, bank reversal is adopted in the lateral plane to reduce the cross-range error. Finally, Mars entry simulation is performed to assess the performance of the adaptive guidance law. The results demonstrate that the proposed guidance law exhibits good performance.

  3. EAS põhjendab toetuseta jätmist: äriplaan on liiga ambitsioonikas / Holger Roonemaa

    Index Scriptorium Estoniae

    Roonemaa, Holger

    2009-01-01

    Pooljuhtelementide ja -struktuuride arendamise ning tootmisega tegelev AS Clifton, kelle toetusetaotluse EAS tagasi lükkas, esitas vaide majandus- ja kommunikatsiooniministeeriumile. Minister Juhan Parts tunnistas EAS-i otsuse kehtetuks. EAS-i põhjendus taotluse tagasilükkamise kohta

  4. Extension of Cherenkov Light LDF Parametrization for Tunka and Yakutsk EAS Arrays

    Indian Academy of Sciences (India)

    A. A. Al-Rubaiee

    2014-12-01

    The Cherenkov light Lateral Distribution Function (LDF) from particles initiated Extensive Air Showers (EAS) with ultrahigh energies ( > 1016 eV) was simulated using CORSIKA program for configuration of Tunka and Yakutsk EAS arrays for different primary particles (p, Fe and O2) and different zenith angles. By depending on the Breit–Wigner function, a parametrization of the Cherenkov light LDF was reconstructed on the basis of this simulation as a function of the primary energy. The comparison of the approximated Cherenkov light LDF with that measured on Tunka and Yakutsk EAS arrays gives the possibility of identification of energy spectrum and mass composition of particles initiating EAS about the knee region of the cosmic ray spectrum. The extrapolation of approximated Cherenkov light LDF for energies 20, 30 and 50 PeV was obtained for different primary particles and different zenith angles.

  5. Cosmic-ray chemical composition from the geomagnetic effect on EAS muons: A simulation study

    CERN Document Server

    Dey, Rajat K

    2016-01-01

    The effect of the geomagnetic Lorentz force on extensive air shower (EAS) charged muon components has been studied in a Monte Carlo (MC) generated simulated data sample. This geomagnetic field (GF) affects the paths of the secondary charged muons in the EAS, causing a local contrast or asymmetry in the abundance of positive and negative muons which is noticeable for some azimuthal and zenith angles. Consequent upon, a transverse separation of positive and negative muons cores of EAS is observed at different azimuthal positions through the EAS core. In the present study using a simulated data sample it is found that the transverse or lateral muon core separation (LMCS) and its maximum value (MLMCS) are quite sensitive to the nature of shower initiating particles, particularly for inclined showers and hence in principle the parameters can be exploited to the measurement of primary cosmic-ray (CR) chemical composition. Possibility of practical realization of the stated method in a real experiment is briefly disc...

  6. MISCIBILITY, SOLUBILITY, AND VISCOSITY MEASUREMENTS FOR R-236EA WITH POTENTIAL LUBRICANTS

    Science.gov (United States)

    The report gives results of miscibility, solubility, and viscosity measurements of refrigerant R-236ea with three potential lubricants. (NOTE: The data were needed to determine the suitability of refrigerant/lubricant combinations for use in refrigeration systems.) The lubricants...

  7. 47 CFR 11.54 - EAS operation during a National Level emergency.

    Science.gov (United States)

    2010-10-01

    ... licensees and DBS providers may choose their two EAS sources, one of which must be a PEP station. (2... operate under the procedures in the National Control Point Procedures. (13) The time of receipt of the EAN...

  8. A Sample of E+A Galaxy Candidates in LAMOST Data Released 2

    CERN Document Server

    Yang, Haifeng; Chen, Xiaoyan; Hou, Wen; Zhang, Jiannan; Du, Wei; Zhang, Jifu; Cai, Jianghui; Guo, Yanxin; Zhang, Shuo; Zhao, Yongheng; Wu, Hong; Wang, Tinggui; Shen, Shiyin; Yang, Ming; Zhang, Yong; Hou, Yonghui

    2015-01-01

    A sample of 70 E+A galaxies are selected from 37, 206 galaxies in the second data release (DR2) of Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) according to the criteria for E+A galaxies defined by Goto, and each of these objects is further visually identified. In this sample, most objects are low redshift E+A galaxies with z < 0.25, and locate in the high latitude sky area with magnitude among 14 to 18 mag in g, r and i bands. A stellar population analysis for the whole sample indicates that the E+A galaxies are characterized by both young and old stellar populations (SPs), and the metal-rich SPs have relatively higher contributions than the metal-poor ones. Additionally, a morphological classification for these objects is performed based on the images taken from the Sloan Digital Sky Survey (SDSS).

  9. Autonomous gliding entry guidance with geographic constraints

    Institute of Scientific and Technical Information of China (English)

    Guo Jie; Wu Xuzhong; Tang Shengjing

    2015-01-01

    This paper presents a novel three-dimensional autonomous entry guidance for relatively high lift-to-drag ratio vehicles satisfying geographic constraints and other path constraints. The guidance is composed of onboard trajectory planning and robust trajectory tracking. For trajectory planning, a longitudinal sub-planner is introduced to generate a feasible drag-versus-energy profile by using the interpolation between upper boundary and lower boundary of entry corridor to get the desired trajectory length. The associated magnitude of the bank angle can be specified by drag profile, while the sign of bank angle is determined by lateral sub-planner. Two-reverse mode is utilized to satisfy waypoint constraints and dynamic heading error corridor is utilized to satisfy no-fly zone constraints. The longitudinal and lateral sub-planners are iteratively employed until all of the path constraints are satisfied. For trajectory tracking, a novel tracking law based on the active disturbance rejection control is introduced. Finally, adaptability tests and Monte Carlo simulations of the entry guidance approach are performed. Results show that the proposed entry guidance approach can adapt to different entry missions and is able to make the vehicle reach the prescribed target point precisely in spite of geographic constraints.

  10. Slow and fast light in SOA-EA structures for phased-array antennas

    DEFF Research Database (Denmark)

    Sales, S.; Öhman, Filip; Bermejo, A.;

    We present an SOA-EA structure for controlling the phase and amplitude of optically fed phased-array antennas. Phase shifts of 40 degrees are obtained through slow and fast light effects by changing only the reverse voltage.......We present an SOA-EA structure for controlling the phase and amplitude of optically fed phased-array antennas. Phase shifts of 40 degrees are obtained through slow and fast light effects by changing only the reverse voltage....

  11. Guidance law based on piecewise constant control for hypersonic gliders

    Science.gov (United States)

    Hull, David G.; Seguin, Jean-Marie

    A midcourse guidance law is developed for the descent of a hypersonic glider to a fixed target on the ground. It is based on an optimal piecewise constant control (N intervals) obtained from an approximate physical model (flat earth, exponential atmosphere, parabolic drag polar, etc). The resulting optimal control equations can be integrated either analytically or by quadrature, and the guidance algorithm requires the solution of 2N+1 nonlinear algebraic equations. The guidance law is implemented in a realistic glider simulation, the intercept is achieved, and final velocities within 14 percent of the true values are obtained for the downrange and crossranges considered.

  12. Sporophytic control of pollen tube growth and guidance in maize.

    Science.gov (United States)

    Lausser, Andreas; Kliwer, Irina; Srilunchang, Kanok-orn; Dresselhaus, Thomas

    2010-03-01

    Pollen tube germination, growth, and guidance (progamic phase) culminating in sperm discharge is a multi-stage process including complex interactions between the male gametophyte as well as sporophytic tissues and the female gametophyte (embryo sac), respectively. Inter- and intra-specific crossing barriers in maize and Tripsacum have been studied and a precise description of progamic pollen tube development in maize is reported here. It was found that pollen germination and initial tube growth are rather unspecific, but an early, first crossing barrier was detected before arrival at the transmitting tract. Pollination of maize silks with Tripsacum pollen and incompatible pollination of Ga1s/Ga1s-maize silks with ga1-maize pollen revealed another two incompatibility barriers, namely transmitting tract mistargeting and insufficient growth support. Attraction and growth support by the transmitting tract seem to play key roles for progamic pollen tube growth. After leaving transmitting tracts, pollen tubes have to navigate across the ovule in the ovular cavity. Pollination of an embryo sac-less maize RNAi-line allowed the role of the female gametophyte for pollen tube guidance to be determined in maize. It was found that female gametophyte controlled guidance is restricted to a small region around the micropyle, approximately 50-100 microm in diameter. This area is comparable to the area of influence of previously described ZmEA1-based short-range female gametophyte signalling. In conclusion, the progamic phase is almost completely under sporophytic control in maize.

  13. PSD Increment Consumption Guidance

    Science.gov (United States)

    This document may be of assistance in applying the New Source Review (NSR) air permitting regulations including the Prevention of Significant Deterioration (PSD) requirements. This document is part of the NSR Policy and Guidance Database. Some documents in the database are a scanned or retyped version of a paper photocopy of the original. Although we have taken considerable effort to quality assure the documents, some may contain typographical errors. Contact the office that issued the document if you need a copy of the original.

  14. 76 FR 63303 - Guidance for Industry on Warnings and Precautions, Contraindications, and Boxed Warning Sections...

    Science.gov (United States)

    2011-10-12

    ... Federal Register of January 24, 2006 (71 FR 3999), FDA issued final guidances on the content and format of...-63304] [FR Doc No: 2011-26297] DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration... October 19, 2009 (74 FR 53507), FDA issued a final guidance on determining established pharmacologic...

  15. Imprint of the atmospheric attenuation process on electron distribution in EAS

    Science.gov (United States)

    Dey, R. K.; Dam, S.; Ray, S.

    2017-04-01

    The lateral density distribution (LDD) of shower particles in an extensive air shower (EAS) experiment is commonly approximated by a particular type of lateral density function (LDF). A standard perception is being used in air shower physics since long, according to which the LDD is assumed to be symmetric about the EAS axis, and the adopted LDF is adequate for the description of the LDD. However, the simulated electron density of a non-vertical EAS is asymmetric. In this work, such asymmetry in the LDD can be qualitatively explained as the atmospheric attenuation suffered by each shower particle. Quantitatively, the asymmetry can be roughly described in terms of a gap length (GL) between the EAS core and the center of the modified density pattern consisting of several equi-density ellipses. This study also validates the use of such a modeling of the atmospheric attenuation on the electromagnetic component in an EAS by investigating the so called GL in simulated density data. A modified LDF is proposed, based on these features of the simulated densities for the purpose of shower reconstruction in EAS experiments. The GL arises from attenuation effect is found to increase with the mass of the shower initiating particle. A different radial dependence of the local age parameter (LAP) is seen, if the modified LDF is applied to simulated electron densities. Primary cosmic-ray mass sensitivity of the LAP is also re-examined.

  16. Imprint of the atmospheric attenuation process on electron distribution in EAS

    Science.gov (United States)

    Dey, R. K.; Dam, S.; Ray, S.

    2016-09-01

    The lateral density distribution (LDD) of shower particles in an extensive air shower (EAS) experiment is commonly approximated by a particular type of lateral density function (LDF). A standard perception is being used in air shower physics since long, according to which the LDD is assumed to be symmetric about the EAS axis, and the adopted LDF is adequate for the description of the LDD. However, the simulated electron density of a non-vertical EAS is asymmetric. In this work, such asymmetry in the LDD can be qualitatively explained as the atmospheric attenuation suffered by each shower particle. Quantitatively, the asymmetry can be roughly described in terms of a gap length (GL) between the EAS core and the center of the modified density pattern consisting of several equi-density ellipses. This study also validates the use of such a modeling of the atmospheric attenuation on the electromagnetic component in an EAS by investigating the so called GL in simulated density data. A modified LDF is proposed, based on these features of the simulated densities for the purpose of shower reconstruction in EAS experiments. The GL arises from attenuation effect is found to increase with the mass of the shower initiating particle. A different radial dependence of the local age parameter (LAP) is seen, if the modified LDF is applied to simulated electron densities. Primary cosmic-ray mass sensitivity of the LAP is also re-examined.

  17. Guidance of Nonlinear Systems

    Science.gov (United States)

    Meyer, George

    1997-01-01

    The paper describes a method for guiding a dynamic system through a given set of points. The paradigm is a fully automatic aircraft subject to air traffic control (ATC). The ATC provides a sequence of way points through which the aircraft trajectory must pass. The way points typically specify time, position, and velocity. The guidance problem is to synthesize a system state trajectory which satisfies both the ATC and aircraft constraints. Complications arise because the controlled process is multi-dimensional, multi-axis, nonlinear, highly coupled, and the state space is not flat. In addition, there is a multitude of possible operating modes, which may number in the hundreds. Each such mode defines a distinct state space model of the process by specifying the state space coordinatization, the partition of the controls into active controls and configuration controls, and the output map. Furthermore, mode transitions must be smooth. The guidance algorithm is based on the inversion of the pure feedback approximations, which is followed by iterative corrections for the effects of zero dynamics. The paper describes the structure and modules of the algorithm, and the performance is illustrated by several example aircraft maneuvers.

  18. Increased cardiogenesis in P19-GFP teratocarcinoma cells expressing the propeptide IGF-1Ea

    Energy Technology Data Exchange (ETDEWEB)

    Poudel, Bhawana [Heart Science Centre, National Heart and Lung Institute, Imperial College, London (United Kingdom); Bilbao, Daniel [EMBL, Mouse Biology Unit, Monterotondo (Italy); Sarathchandra, Padmini; Germack, Renee [Heart Science Centre, National Heart and Lung Institute, Imperial College, London (United Kingdom); Rosenthal, Nadia [Heart Science Centre, National Heart and Lung Institute, Imperial College, London (United Kingdom); Australian Regenerative Medicine Institute, Monash University, Melbourne (Australia); Santini, Maria Paola, E-mail: m.santini@imperial.ac.uk [Heart Science Centre, National Heart and Lung Institute, Imperial College, London (United Kingdom)

    2011-12-16

    Highlights: Black-Right-Pointing-Pointer In this study, we explored the function of IGF-1Ea propeptide in inducing cardiogenesis of stem cells. Black-Right-Pointing-Pointer IGF-1Ea promoted cardiac mesodermal induction in uncommitted cells. Black-Right-Pointing-Pointer Under differentiation condition, IGF-1Ea increased expression of cardiac differentiation markers. Black-Right-Pointing-Pointer Furthermore, it promoted formation of finely organized sarcomeric structure. Black-Right-Pointing-Pointer IGF-1Ea propeptide may be a good candidate to improve production of cardiomyocytes from pluripotent cells. -- Abstract: The mechanism implicated in differentiation of endogenous cardiac stem cells into cardiomyocytes to regenerate the heart tissue upon an insult remains elusive, limiting the therapeutical goals to exogenous cell injection and/or gene therapy. We have shown previously that cardiac specific overexpression of the insulin-like growth factor 1 propeptide IGF-1Ea induces beneficial myocardial repair after infarct. Although the mechanism is still under investigation, the possibility that this propeptide may be involved in promoting stem cell differentiation into the cardiac lineage has yet to be explored. To investigate whether IGF-1Ea promote cardiogenesis, we initially modified P19 embryonal carcinoma cells to express IGF-1Ea. Taking advantage of their cardiomyogenic nature, we analyzed whether overexpression of this propeptide affected cardiac differentiation program. The data herein presented showed for the first time that constitutively overexpressed IGF-1Ea increased cardiogenic differentiation program in both undifferentiated and DMSO-differentiated cells. In details, IGF-1Ea overexpression promoted localization of alpha-actinin in finely organized sarcomeric structure compared to control cells and upregulated the cardiac mesodermal marker NKX-2.5 and the ventricular structural protein MLC2v. Furthermore, activated IGF-1 signaling promoted cardiac

  19. DECOVALEX-THMC Project. Task B. Understanding and characterizing the excavation disturbed zone (EDZ). Final Report (EDZ Guidance Document) Characterising and Modelling the Excavation Damaged Zone (EDZ) in Crystalline Rocks in the Context of Radioactive Waste Disposal

    Energy Technology Data Exchange (ETDEWEB)

    Hudson, John A. (Imperial College and Rock Engineering Consultants (United Kingdom)); Baeckstroem, Ann; Lanru Jing (Royal lnstitute of Technology, Stockholm (Sweden)); Rutqvist, Jonny (Lawrence Berkeley National Laboratory (United States)) (eds.) (and others)

    2008-06-15

    This report is intended as a Guidance Document explaining current knowledge about the nature of and potential for thermo-hydro-mechanical-chemical modelling of the Excavation Damaged Zone (EDZ) around the excavations for an underground radioactive waste repository. In Part 1 of the report, the disturbances associated with excavation are explained together with reviews of Workshops that have been held on the subject. The manifold aspects of the EDZ are discussed under the three headings of the rock mass response to tunnelling, the influence of the excavation method, and EDZ characterisation methods. The evolution of the repository over thousands of years is qualitatively described via the subjects of time-dependent effects and stress redistribution, thermal effects, hydrogeological effects, and chemical effects. The first part of the document concludes with a discussion of uncertainties and limitations in measuring and characterising the EDZ. In Part 2 of the report, the results of a DECOVALEX research programme on modelling the EDZ are presented. Initially, the research involved the physical testing and computer modelling of the failure behaviour of a rock specimen in uniaxial compression. Four research teams used four different models to simulate the complete stress-strain curve for Aevroe granite from the Swedish Aespoe Hard Rock Laboratory. Conclusions are then made concerning the overall capabilities of these models. Subsequent research extended the work to computer simulation of the evolution of the repository using a 'wall block model' and a 'near-field model'. This included assessing the evolution of stress, failure and permeability and time dependent effects during repository evolution. In both sets of computer modelling, the types of codes used were an Elasto-Plastic Cellular Automaton (EPCA), the FRACOD boundary element (BEM) code with discrete fracture propagation, the THAMES finite element (FEM) code, and PFC, a distinct element

  20. Terminal area automatic navigation, guidance and control research using the Microwave Landing System (MLS). Part 5: Design and development of a Digital Integrated Automatic Landing System (DIALS) for steep final approach using modern control techniques

    Science.gov (United States)

    Halyo, N.

    1983-01-01

    The design and development of a 3-D Digital Integrated Automatic Landing System (DIALS) for the Terminal Configured Vehicle (TCV) Research Aircraft, a B-737-100 is described. The system was designed using sampled data Linear Quadratic Gaussian (LOG) methods, resulting in a direct digital design with a modern control structure which consists of a Kalman filter followed by a control gain matrix, all operating at 10 Hz. DIALS uses Microwave Landing System (MLS) position, body-mounted accelerometers, as well as on-board sensors usually available on commercial aircraft, but does not use inertial platforms. The phases of the final approach considered are the localizer and glideslope capture which may be performed simultaneously, localizer and steep glideslope track or hold, crab/decrab and flare to touchdown. DIALS captures, tracks and flares from steep glideslopes ranging from 2.5 deg to 5.5 deg, selected prior to glideslope capture. Digital Integrated Automatic Landing System is the first modern control design automatic landing system successfully flight tested. The results of an initial nonlinear simulation are presented here.

  1. A Further Look at X-33 Entry Guidance and Beyond

    Science.gov (United States)

    Lu, Ping

    1999-01-01

    An entry guidance design developed at Iowa State University (ISU) for the X-33 advanced technology demonstrator is outlined and compared with the X-33 entry guidance algorithms developed at NASA Marshall. Both designs are based on the Space Shuttle entry guidance concept, but significant improvements have been made to enhance the performance and reduce the complexity. The ISU design was incorporated into MAVERIC, a high fidelity vehicle simulation software for the X-33, and evaluated in Monte Carlo simulations against random dispersions in propulsion system, wind and atmospheric properties, aerodynamic coefficients, interaction between propulsion and aerodynamics, and navigation data. The simulations clearly demonstrated the capability and precision of the ISU entry guidance design in successfully guiding the X-33 in some rather difficult flight scenarios. As the entry guidance development for the X-33 is completing, this report also offers some review of the strength and limitations of the current Shuttle-based entry guidance framework, and finally some potential candidates for next generation of more capable and cost-effective entry guidance designs are discussed.

  2. Guidance at the educational marketplace

    DEFF Research Database (Denmark)

    Lystbæk, Christian Tang

    in educational policies and institutions. As educational systems have expanded and, further, have been restructured with the expansion of choice opportunities since the 1980s, guidance has become prioritized as a form of counseling or coaching, which can support students. Thus, guidance has become an important...

  3. Guidance in the Secondary School

    Science.gov (United States)

    Kumar, V. Jurist Lional

    2010-01-01

    Secondary School Students face a lot of problems in their body as well as in mind due to puberty that tends to adolescence stage. Adolescence has peculiar characters of their own. They need proper Guidance and Counselling to tackle their own problems. Guidance is described as a counselling service to assist the individual in achieving self…

  4. Innovative Approaches to Career Guidance.

    Science.gov (United States)

    Freeman, Andrew R.

    A key part of a broad-based approach to career education in Australian schools is vocational/career guidance. Various vocational guidance programs have been developed for specific groups in Australian society, including work experience, caravans, and micrographics technology for the handicapped; pre-employment courses and a family education center…

  5. Interstitial guidance of cancer invasion.

    Science.gov (United States)

    Gritsenko, Pavlo G; Ilina, Olga; Friedl, Peter

    2012-01-01

    Cancer cell invasion into healthy tissues develops preferentially along pre-existing tracks of least resistance, followed by secondary tissue remodelling and destruction. The tissue scaffolds supporting or preventing guidance of invasion vary in structure and molecular composition between organs. In the brain, the guidance is provided by myelinated axons, astrocyte processes, and blood vessels which are used as invasion routes by glioma cells. In the human breast, containing interstitial collagen-rich connective tissue, disseminating breast cancer cells preferentially invade along bundled collagen fibrils and the surface of adipocytes. In both invasion types, physical guidance prompted by interfaces and space is complemented by molecular guidance. Generic mechanisms shared by most, if not all, tissues include (i) guidance by integrins towards fibrillar interstitial collagen and/or laminins and type IV collagen in basement membranes decorating vessels and adipocytes, and, likely, CD44 engaging with hyaluronan; (ii) haptotactic guidance by chemokines and growth factors; and likely (iii) physical pushing mechanisms. Tissue-specific, resticted guidance cues include ECM proteins with restricted expression (tenascins, lecticans), cell-cell interfaces, and newly secreted matrix molecules decorating ECM fibres (laminin-332, thrombospondin-1, osteopontin, periostin). We here review physical and molecular guidance mechanisms in interstitial tissue and brain parenchyma and explore shared principles and organ-specific differences, and their implications for experimental model design and therapeutic targeting of tumour cell invasion.

  6. Restructuring Guidance and Counseling Programs.

    Science.gov (United States)

    Snyder, Beverly A.; Daly, Timothy P.

    1993-01-01

    Briefly reviews counseling profession's call for revitalization and transformation in school counseling and guidance programs. Summarizes one school system's efforts during late 1980s and early 1990s to transform its program from services and crisis orientation into a comprehensive developmental model based on Myrick's developmental guidance and…

  7. Characterization of a new ViI-like Erwinia amylovora bacteriophage phiEa2809.

    Science.gov (United States)

    Lagonenko, Alexander L; Sadovskaya, Olga; Valentovich, Leonid N; Evtushenkov, Anatoly N

    2015-04-01

    Erwinia amylovora is a Gram-negative plant pathogenic bacteria causing fire blight disease in many Rosaceae species. A novel E. amylovora bacteriophage, phiEa2809, was isolated from symptomless apple leaf sample collected in Belarus. This phage was also able to infect Pantoea agglomerans strains. The genome of phiEa2809 is a double-stranded linear DNA 162,160 bp in length, including 145 ORFs and one tRNA gene. The phiEa2809 genomic sequence is similar to the genomes of the Serratia plymutica phage MAM1, Shigella phage AG-3, Dickeya phage vB DsoM LIMEstone1 and Salmonella phage ViI and lacks similarity to described E. amylovora phage genomes. Based on virion morphology (an icosahedral head, long contractile tail) and genome structure, phiEa2809 was classified as a member of Myoviridae, ViI-like bacteriophages group. PhiEa2809 is the firstly characterized ViI-like bacteriophage able to lyse E. amylovora.

  8. A method of observing cherenkov light from extensive air shower at Yakutsk EAS array

    Science.gov (United States)

    Timofeev, Lev; Anatoly, Ivanov

    2016-07-01

    Proposed a new method for measuring the cherenkov light from the extensive air shower (EAS) of cosmic rays (CR), which allows to determine not only the primary particle energy and angle of arrival, but also the parameters of the shower in the atmosphere - the maximum depth and "age". For measurements Cherenkov light produced by EAS is proposed to use a ground network of wide-angle telescopes which are separated from each other by a distance 100-300 m depending on the total number of telescopes operating in the coincidence signals, acting autonomously, or includes a detector of the charged components, radio waves, etc. as part of EAS. In a results such array could developed, energy measurement and CR angle of arrival data on the depth of the maximum and the associated mass of the primary particle generating by EAS. This is particularly important in the study of galactic cosmic ray in E> 10^14 eV, where currently there are no direct measurements of the maximum depth of the EAS.

  9. Cherry Valley National Wildlife Refuge Final Feasibility Study and Environmental Assessment

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — In accordance with the National Environmental Policy Act (NEPA), as amended, the Service has developed a Final EA in response to the Cherry Valley National Wildlife...

  10. Family-based association study of dopaminergic genes polymorphisms and EAS temperamental traits [Polimorfizmy w genach systemu dopaminergicznego a cechy temperamentu EAS – rodzinne badanie asocjacyjne

    Directory of Open Access Journals (Sweden)

    Dragan, Wojciech Ł.

    2013-04-01

    Full Text Available Aim. The aim of the present study was to identify relations between several polymorphisms in dopamine genes (DRD2,DRD3, DRD4, SNAP-25, ANKK1and DAT1 and temperamental traits distinguished in the EAS theory. In this study the family-based method was used.Method. The study was run on 149 biological families with one or two children aged 3-12. Temperamental data were obtained using Buss and Plomin EAS-C Temperament Questionnaire.Results. Significant associations between two SNPs in the SNAP-25 gene (rs363039 and rs363050 and shyness was found. Significant relationships of this trait with haplotypes in DAT1 and SNAP-25 genes was also identified. Conclusion. The data collected suggest that variability in dopamine genes may have impact on the development of temperamental shyness, which is recognized as a fear of strangers.

  11. Re-Entry Guidance Using an Energy-State Equation

    Science.gov (United States)

    Abe, Akio; Shimada, Yuzo; Uchiyama, Kenji

    This paper presents a new guidance and control system for a re-entry vehicle. In the conventional drag acceleration control system employed for the present space shuttles, the velocity is an unobservable state variable and the associated pole tends to be unstable. Therefore, in this study, a condition which allows all the states to be observable is introduced using a state-space linearization method. It is also shown that energy and its rate are appropriate for the state variables. A guidance law is analytically derived on the basis of the obtained state equation with respect to the energy by solving a two-point boundary-value problem. Furthermore, a tracking control system is designed to make the position, velocity, and flight path angle of the vehicle track the reference states generated in the guidance system. Finally, numerical simulation is performed to verify the validity of the obtained plant expression, and the effectiveness of the proposed guidance and control system.

  12. RH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2008-01-12

    The purpose of this program guidance document is to provide the technical requirements for use, operation, inspection, and maintenance of the RH-TRU 72-B Waste Shipping Package (also known as the "RH-TRU 72-B cask") and directly related components. This document complies with the requirements as specified in the RH-TRU 72-B Safety Analysis Report for Packaging (SARP), and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9212. If there is a conflict between this document and the SARP and/or C of C, the C of C shall govern. The C of C states: "...each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." It further states: "...each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP tasks the Waste Isolation Pilot Plant (WIPP) Management and Operating (M&O) Contractor with assuring the packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with Title 10 Code of Federal Regulations (CFR) §71.8, "Deliberate Misconduct." Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) shall be notified immediately. The CBFO will evaluate the issue and notify the NRC if required.In accordance with 10 CFR Part 71, "Packaging and Transportation of Radioactive Material," certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21, "Reporting of Defects and Noncompliance," regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a

  13. RH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions LLC

    2006-11-07

    The purpose of this program guidance document is to provide the technical requirements for use, operation, inspection, and maintenance of the RH-TRU 72-B Waste Shipping Package and directly related components. This document complies with the requirements as specified in the RH-TRU 72-B Safety Analysis Report for Packaging (SARP), and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9212. If there is a conflict between this document and the SARP and/or C of C, the C of C shall govern. The C of C states: "...each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, Operating Procedures, of the application." It further states: "...each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, Acceptance Tests and Maintenance Program of the Application." Chapter 9.0 of the SARP tasks the Waste Isolation Pilot Plant (WIPP) Management and Operating (M&O) Contractor with assuring the packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC-approved, users need to be familiar with 10 Code of Federal Regulations (CFR) §71.8, "Deliberate Misconduct." Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the U.S. Department of Energy (DOE) Carlsbad Field Office (CBFO) shall be notified immediately. CBFO will evaluate the issue and notify the NRC if required. In accordance with 10 CFR Part 71, "Packaging and Transportation of Radioactive Material," certificate holders, packaging users, and contractors or subcontractors who use, design, fabricate, test, maintain, or modify the packaging shall post copies of (1) 10 CFR Part 21, "Reporting of Defects and Noncompliance," regulations, (2) Section 206 of the Energy Reorganization Act of 1974, and (3) NRC Form 3, Notice to Employees. These documents must be posted in a conspicuous location where the activities subject to

  14. Separation,Purification and Insecticidal Activity of Cry8Ea2 Protein from Bacillus thuringiensis%苏云金杆菌Cry8Ea2蛋白的分离纯化及生物活性测定

    Institute of Scientific and Technical Information of China (English)

    王伟; 郭巍; 徐大庆; 孙伟明; 刘大群; 李瑞军

    2012-01-01

    Cry8 Ea2蛋白是一种新型苏云金杆菌杀虫晶体蛋白.通过穿梭载体pSXY422b将cry8Ea2导入Bt无晶体突变菌株中,获得工程菌HD8Ea2.Cry8Ea2蛋白在工程菌中获得表达.通过分子筛层析,成功获得纯化的130 kDa活性毒素蛋白.用改进的生物活性测定方法进行Cry8Ea2蛋白对华北大黑鳃金龟和暗黑鳃金龟一龄幼虫的杀虫活性测定,LC50分别为0.267 9μg/mL和0.071 9μg/mL.研究首次发现Cry8Ea2蛋白对华北大黑鳃金龟具有较高毒力,拓展了该蛋白的杀虫谱,为转基因工程提供了新资源.%Cry8Ea2 protein is a kind of insecticidal crystal protein of Bacillus thuringiensis. In this study, cry8Ea2 was cloned into E. coli- B. thuringiensist shuttle vector pSXY422b,resulting from recombinant pScry8Ea2, and pScry8Ea2 was transformed into the Bt, acrystalliferous mutant generating HD8Ea2 engineering strain. Cry8Ea2 protein was successfully expressed in HD8Ea2 stain. By anion exchange chromatography on molecular sieve chroma-tography,130 kDa of toxin protein Cry8Ea2 was purified. The activities of the Cry8Ea2 toxin were evaluated by improved bioassays, and the LC50 value to neonates of Holotrichia oblita and Holotrichia paralella was 0. 267 9 μg/mL and 0.071 9 μg/mL, respectively. Insecticidal activity of Cry8Ea2 to Holotrichia oblita was firstly reported in this study ,which will broaden the protein insecticidal spectrum and provide new resources for genetically modified project.

  15. International Conference on Harmonisation; S10 Photosafety Evaluation of Pharmaceuticals; guidance for industry; availability. Notice.

    Science.gov (United States)

    2015-01-27

    The Food and Drug Administration (FDA) is announcing the availability of a guidance for industry entitled "S10 Photosafety Evaluation of Pharmaceuticals.'' The guidance was prepared under the auspices of the International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH). This guidance outlines details on when photosafety testing is warranted and on possible assessment strategies; it should be read in conjunction with the ICH M3(R2) guidance, section XIV(14) Photosafety Testing. The purpose of the guidance is to recommend international standards for photosafety assessment and to harmonize such assessments that support human clinical trials and marketing authorization for pharmaceuticals. This guidance finalizes the draft guidance issued on February 4, 2013.

  16. Pandemic influenza guidance for corporations.

    Science.gov (United States)

    2011-06-01

    The purpose of this guidance document is to assist members of the American College of Occupational and Environmental Medicine (ACOEM), and the organizations for which they work, in managing the impact of a pandemic of influenza or other contagious respiratory disease on patients, employees, and business. This guidance document outlines actions to take before and during an influenza pandemic on the basis of two main strategies: (1) reducing the spread of the virus within facilities; and (2) providing medical care and medical surveillance to client/patient populations. Facilities in which ACOEM members serve include government agencies and the military, universities, and corporations, which generally have multiple locations/sites and their own medical staff, with members responsible for medical care and disease control. This guidance is for organizations with outpatient occupational medicine services, to be used as appropriate. Medical centers should also use guidance that addresses additional employee and external patient care needs.1–3 The ACOEM fully supports implementation of occupational influenza programs that conform with guidance from the Centers for Disease Control and Prevention (CDC), with other guidance from the US Department of Health and Human Services (DHHS), and Occupational Safety and Health Administration (OSHA) regulations and guidance.

  17. Hadronic interactions and EAS muon pseudorapidities investigated with the Muon Tracking Detector in KASCADE-Grande

    Energy Technology Data Exchange (ETDEWEB)

    Zabierowski, J., E-mail: janzab@zpk.u.lodz.p [Soltan Institute for Nuclear Studies, P.O. Box 447, 90950 Lodz (Poland); Apel, W.D. [Institut fuer Kernphysik, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany); Arteaga, J.C. [Institut fuer Experimentelle Kernphysik, Universitaet Karlsruhe D-76021 Karlsruhe (Germany); Badea, F.; Bekk, K. [Institut fuer Kernphysik, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany); Bertaina, M. [Dipartimento di Fisica Generale dell' Universita, 10125 Torino (Italy); Bluemer, H. [Institut fuer Experimentelle Kernphysik, Universitaet Karlsruhe D-76021 Karlsruhe (Germany); Institut fuer Kernphysik, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany); Bozdog, H. [Institut fuer Kernphysik, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany); Brancus, I.M. [National Institute of Physics and Nuclear Engineering, 7690 Bucharest (Romania); Brueggemann, M.; Buchholz, P. [Fachbereich Physik, Universitaet Siegen, 57068 Siegen (Germany); Cantoni, E. [Dipartimento di Fisica Generale dell' Universita, 10125 Torino (Italy); Istituto di Fisica dello Spazio Interplanetario, INAF, 10133 Torino (Italy); Chiavassa, A. [Dipartimento di Fisica Generale dell' Universita, 10125 Torino (Italy); Cossavella, F. [Institut fuer Experimentelle Kernphysik, Universitaet Karlsruhe D-76021 Karlsruhe (Germany); Daumiller, K. [Institut fuer Kernphysik, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany); Souza, V. de [Institut fuer Experimentelle Kernphysik, Universitaet Karlsruhe D-76021 Karlsruhe (Germany); Di Pierro, F. [Dipartimento di Fisica Generale dell' Universita, 10125 Torino (Italy); Doll, P.; Engel, R.; Engler, J. [Institut fuer Kernphysik, Forschungszentrum Karlsruhe, 76021 Karlsruhe (Germany)

    2009-12-15

    The Muon Tracking Detector in the KASCADE-Grande EAS experiment allows the precise measurement of shower muon directions up to 700 m distance from the shower center. This directional information is used to study the pseudorapidity of muons in EAS, closely related to the pseudorapidity of their parent mesons. Moreover, the mean value of muon pseudorapidity in a registered shower reflects the longitudinal development of its hadronic component. All of this makes it a good tool for testing hadronic interaction models. The possibilities of such tests given by the KASCADE-Grande experimental setup are discussed and an example of the obtained muon pseudorapidity spectrum is shown.

  18. Optimal mutation rates for the (1+λ) EA on OneMax

    DEFF Research Database (Denmark)

    Gießen, Christian; Witt, Carsten

    2016-01-01

    We study the (1 + λ) EA with mutation probability c/n, where c > 0 is a constant, on the ONEMAX problem. Using an improved variable drift theorem, we show that upper and lower bounds on the expected runtime of the (1+λ) EA obtained from variable drift theorems are at most apart by a small lower...... order term if the exact drift is known. This reduces the analysis of expected optimization time to finding an exact expression for the drift. We then give an exact closed-form expression for the drift and develop a method to approximate it very efficiently, enabling us to determine approximate optimal...

  19. A Combined group EA-PROMETHEE method for a supplier selection problem

    Directory of Open Access Journals (Sweden)

    Hamid Reza Rezaee Kelidbari

    2016-07-01

    Full Text Available One of the important decisions which impacts all firms’ activities is the supplier selection problem. Since the 1950s, several works have addressed this problem by treating different aspects and instances. In this paper, a combined multiple criteria decision making (MCDM technique (EA-PROMETHEE has been applied to implement a proper decision making. To this aim, after reviewing the theoretical background regarding to supplier selection, the extension analysis (EA is used to determine the importance of criteria and PROMETHEE for appraisal of suppliers based on the criteria. An empirical example illustrated the proposed approach.

  20. Comparison of EPOS and QGSJET-II in EAS Simulation using CORSIKA code

    CERN Document Server

    Thakuria, Chabin Ch

    2012-01-01

    In this work we compare the predictions of two representative hadronic interaction models, EPOS 1.99, and QGSJET II-03 with several extensive air showers (EAS) parameters for proton and iron primaries in the energy range $10^{17}$ - $10^{19} eV$ using CORSIKA-6990. The EAS parameters depth of shower maximum, shower size, size of muon shower, muon number distribution, electron number distribution,size of hadron shower, hadron energy sum, electron muon correlations, and, hadron energy spectra are studied in this paper.

  1. Sensitivity of EAS measurements to the energy spectrum of muons

    Science.gov (United States)

    Espadanal, J.; Cazon, L.; Conceição, R.

    2017-01-01

    We have studied how the energy spectrum of muons at production affects some of the most common measurements related to muons in extensive air shower studies, namely, the number of muons at the ground, the slope of the lateral distribution of muons, the apparent muon production depth, and the arrival time delay of muons at ground. We found that by changing the energy spectrum by an amount consistent with the difference between current models (namely EPOS-LHC and QGSJET-II.04), the muon surface density at ground increases 5% at 20° zenith angle and 17% at 60° zenith angle. This effect introduces a zenith angle dependence on the reconstructed number of muons which might be experimentally observed. The maximum of the muon production depth distribution at 40° increases ∼ 10 g/cm2 and ∼ 0 g/cm2 at 60°, which, from pure geometrical considerations, increases the arrival time delay of muons. There is an extra contribution to the delay due to the subluminal velocities of muons of the order of ∼ 3 ns at all zenith angles. Finally, changes introduced in the logarithmic slope of the lateral density function are less than 2%.

  2. RH Packaging Program Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Washington TRU Solutions, LLC

    2003-08-25

    The purpose of this program guidance document is to provide technical requirements for use, operation, inspection, and maintenance of the RH-TRU 72-B Waste Shipping Package and directly related components. This document complies with the requirements as specified in the RH-TRU 72-B Safety Analysis Report for Packaging (SARP), and Nuclear Regulatory Commission (NRC) Certificate of Compliance (C of C) 9212. If there is a conflict between this document and the SARP and/or C of C, the SARP and/or C of C shall govern. The C of C states: ''...each package must be prepared for shipment and operated in accordance with the procedures described in Chapter 7.0, ''Operating Procedures,'' of the application.'' It further states: ''...each package must be tested and maintained in accordance with the procedures described in Chapter 8.0, ''Acceptance Tests and Maintenance Program of the Application.'' Chapter 9.0 of the SARP tasks the Waste Isolation Pilot Plant (WIPP) Management and Operating (M&O) contractor with assuring the packaging is used in accordance with the requirements of the C of C. Because the packaging is NRC approved, users need to be familiar with 10 CFR {section} 71.11, ''Deliberate Misconduct.'' Any time a user suspects or has indications that the conditions of approval in the C of C were not met, the Carlsbad Field Office (CBFO) shall be notified immediately. CBFO will evaluate the issue and notify the NRC if required. This document details the instructions to be followed to operate, maintain, and test the RH-TRU 72-B packaging. This Program Guidance standardizes instructions for all users. Users shall follow these instructions. Following these instructions assures that operations are safe and meet the requirements of the SARP. This document is available on the Internet at: ttp://www.ws/library/t2omi/t2omi.htm. Users are responsible for ensuring they are using the current

  3. CAREER GUIDANCE EXPERIENCE ABROAD

    Directory of Open Access Journals (Sweden)

    Sergey N. Tolstoguzov

    2015-01-01

    Full Text Available The aim of this paper is to describe the experience of careeroriented activities carried out with students of schools in developed and developing countries. Career Guidance in Russia, despite the vast experience of its implementation, is experiencing serious difficulties. In this regard, it is important to take into account the international experience career-oriented activities, such as in the developed countries of North America and the European Union as well as in several Asian countries with rapidly growing economies and a large demographic potential, taking into account the best variants for the Russian education system. Methods. The experience of career-oriented work undertaken with pupils of the USA, Canada, Israel, France, UK, Germany, Denmark, Sweden, Japan, Singapore, China and India is shown on the basis of the comparative analysis of different publications and information sources. The author has made an attempt to generalize the principles of psycho-pedagogical and administrative assistance in professional self-determination of senior pupils abroad. Scientific novelty. The approaches to career-oriented activities in countries with different levels of economic development are compared for the first time. Some principles are revealed. Firstly, the higher the income level per capita in the country, the greater attention is given to vocational guidance. The politics in the developed countries is based on interests of the individual: children’s acquaintance with the world of professions begins already at younger school and the moment of definitive selfdetermination is postponed till the end of their senior stage of education; the possibility of direction change of professional preparation in case of detection of discrepancy of qualities of the pupil to originally selected profile is provided. Career-oriented activity in developing countries, on the contrary, is rigidly coordinated to requirements of economy and a labour market

  4. CDM Convective Forecast Planning guidance

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The CDM Convective Forecast Planning (CCFP) guidance product provides a foreast of en-route aviation convective hazards. The forecasts are updated every 2 hours and...

  5. Response to work activity guidance

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This memorandum is concerning the request from the FY95 Platte-Kansas Rivers Ecosystem Work Activity Guidance for refuge managers to review the purposes of refuges...

  6. TSCA Inventory Policy and Guidance

    Science.gov (United States)

    A list of numerous policy statements and guidance documents on how to identify certain chemical substances for the purpose of assigning unique and unambiguous descriptions tor each substance listed on the Inventory.

  7. Guidance Systems of Fighter Aircraft

    Directory of Open Access Journals (Sweden)

    K.N. Rajanikanth

    2005-07-01

    Full Text Available Mission performance of a fighter aircraft is crucial for survival and strike capabilities in todays' aerial warfare scenario. The guidance functions of such an aircraft play a vital role inmeeting the requirements and accomplishing the mission success. This paper presents the requirements of precision guidance for various missions of a fighter aircraft. The concept ofguidance system as a pilot-in-loop system is pivotal in understanding and designing such a system. Methodologies of designing such a system are described.

  8. Guidance Systems of Fighter Aircraft

    OpenAIRE

    K.N. Rajanikanth; Rao, R S; P. S. Subramanyam; Ajai Vohra

    2005-01-01

    Mission performance of a fighter aircraft is crucial for survival and strike capabilities in todays' aerial warfare scenario. The guidance functions of such an aircraft play a vital role inmeeting the requirements and accomplishing the mission success. This paper presents the requirements of precision guidance for various missions of a fighter aircraft. The concept ofguidance system as a pilot-in-loop system is pivotal in understanding and designing such a system. Methodologies of designing s...

  9. Guidance molecules in lung cancer

    OpenAIRE

    Nasarre, Patrick; Potiron, Vincent; Drabkin, Harry; Roche, Joëlle

    2010-01-01

    Guidance molecules were first described in the nervous system to control axon outgrowth direction. They are also widely expressed outside the nervous system where they control cell migration, tissue development and establishment of the vascular network. In addition, they are involved in cancer development, tumor angiogenesis and metastasis. This review is primarily focused on their functions in lung cancer and their involvement in lung development is also presented. Five guidance molecule fam...

  10. Data of evolutionary structure change: 1LCTA-1A8EA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available dbID> A 1LCTA LYLGS--GYFTA ...1LCTA-1A8EA 1LCT 1A8E A A -RSVQWCAVSNPEATKCFQWQRNMRKV---RGPPVSCIK...nt> 0 1LCT A 1LCT...A NMRKV---RGPPV ...ure>HHHH --- ure> ATOM 171 CA ASN A 25 4.724 22.416 67.259 1.

  11. HEAT TRANSFER EVALUATION OF HFC-236EA AND CFC-114 IN CONDENSATION AND EVAPORATION

    Science.gov (United States)

    The report gives results of a heat transfer evaluation of the refrigerants hexafluoropropane (HFC-236ea) and 1,1,2,2-dichloro-tetrafluoroethane (CFC-114). (NOTE: With the mandatory phase-out of chlorofluorocarbons (CFCs), as dictated by the Montreal Protocol and Clean Air Act Ame...

  12. HEAT TRANSFER EVALUATION OF HFC-236EA WITH HIGH PERFORMANCE ENHANCED TUBES IN CONDENSATION AND EVAPORATION

    Science.gov (United States)

    The report gives results of an evaluation of the heat transfer performance of pure hydrofluorocarbon (HFC)-236ea for high performance enhanced tubes which had not been previously used in Navy shipboard chillers. Shell-side heat transfer coefficient data are presented for condensa...

  13. MMAS Versus Population-Based EA on a Family of Dynamic Fitness Functions

    DEFF Research Database (Denmark)

    Lissovoi, Andrei; Witt, Carsten

    2015-01-01

    We study the behavior of a population-based EA and the Max–Min Ant System (MMAS) on a family of deterministically-changing fitness functions, where, in order to find the global optimum, the algorithms have to find specific local optima within each of a series of phases. In particular, we prove...

  14. MMAS vs. Population-based EA on a family of dynamic fitness functions

    DEFF Research Database (Denmark)

    Lissovoi, Andrei; Witt, Carsten

    2014-01-01

    We study the behavior of a population-based EA and the Max-Min Ant System (MMAS) on a family of deterministically-changing fitness functions, where, in order to find the global optimum, the algorithms have to find specific local optima within each of a series of phases. In particular, we prove...

  15. Utility of 64-row MDCT in assessment of neonates with congenital EA and distal TEF

    Directory of Open Access Journals (Sweden)

    Hosam El-Deen Galal Mohamed El-Malah

    2015-12-01

    Conclusion: Preoperative MDCT scan with MPVR, 3D TL-VR of 64-row MDCT which is a noninvasive technique could provide more accurate information about the assessment of the origin of the fistula, the distal esophageal pouches and inter-pouch distance in neonates with EA and distal TEF.

  16. 75 FR 45075 - Airworthiness Directives; Eclipse Aerospace, Inc. Model EA500 Airplanes

    Science.gov (United States)

    2010-08-02

    ... information system and the airplane flight manuals. The FAA incorrectly referenced the applicability for Model EA500 airplanes with certain serial numbers (SNs) of this proposed AD as ``000039 through 000104, 000113... incorporating changes to the electronic flight information system and the airplane flight manuals. In the...

  17. 47 CFR 90.691 - Emission mask requirements for EA-based systems.

    Science.gov (United States)

    2010-10-01

    ... frequency block greater than 37.5 kHz, the power of any emission shall be attenuated below the transmitter... 47 Telecommunication 5 2010-10-01 2010-10-01 false Emission mask requirements for EA-based systems... SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Regulations Governing Licensing and Use...

  18. Data of evolutionary structure change: 1D7EA-1OTAA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1D7EA-1OTAA 1D7E 1OTA A A ---VAFGSEDIENTLAKMDDGQLDGLAFGAIQLDGDGNI...ne>VAL CA 559 PHE CA 524 1OTA A 1OTAA KKALSGDSYWVF E EE...9981689453 7.820000171661377 tion> 0.8790000081062...1399 0.36500000953674316 -0.3330000042915344 -0.25200000405311584 -0.9089999794960022

  19. 75 FR 39472 - Airworthiness Directives; Eclipse Aerospace, Inc. Model EA500 Airplanes

    Science.gov (United States)

    2010-07-09

    ... Federal Aviation Administration 14 CFR Part 39 RIN 2120-AA64 Airworthiness Directives; Eclipse Aerospace... directive (AD) for certain Eclipse Aerospace, Inc. (Eclipse) Model EA500 airplanes. This proposed AD would... proposed AD, contact Eclipse Aerospace, Incorporated, 2503 Clark Carr Loop, SE., Albuquerque, New...

  20. D2.1 - An EA Active, Problem Based Learning Methodology - EAtrain2

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Georgsen, Marianne; Buus, Lillian

    This deliverable reports on the work undertaken in work package 2 with the key objective to develop a learning methodology for web 2.0 mediated Enterprise Architecture (EA) learning building on a problem based learning (PBL) approach. The deliverable reports not only on the methodology but also...

  1. A Conceptual Critique of the EA:es Comparison in the Comprehensive Rorschach System.

    Science.gov (United States)

    Kleiger, James H.; Exner, John E., Jr.

    1992-01-01

    The EA:es index (part of the Comprehensive Rorschach System) is discussed, demonstrating how conceptual difficulties and abstract jargon can result in misleading and contradictory inferences. The comments of J. E. Exner, Jr., and the response of J. H. Kleiger concern the importance of theory in Rorschach interpretation. (SLD)

  2. Self-Adaptive Operator Scheduling using the Religion-Based EA

    DEFF Research Database (Denmark)

    Thomsen, Rene; Krink, Thiemo

    2002-01-01

    The optimal choice of the variation operators mutation and crossover and their parameters can be decisive for the performance of evolutionary algorithms (EAs). Usually the type of the operators (such as Gaussian mutation) remains the same during the entire run and the probabilistic frequency of t...

  3. Self-Adaptive Operator Scheduling using the Religion-Based EA

    DEFF Research Database (Denmark)

    Thomsen, Rene; Krink, Thiemo

    2002-01-01

    The optimal choice of the variation operators mutation and crossover and their parameters can be decisive for the performance of evolutionary algorithms (EAs). Usually the type of the operators (such as Gaussian mutation) remains the same during the entire run and the probabilistic frequency of t...

  4. Revised analysis of the (1+1) EA for the minimum spanning tree problem

    DEFF Research Database (Denmark)

    Witt, Carsten

    2014-01-01

    We revisit the classical analysis of the (1+1) EA for the minimum spanning tree problem in the case that nothing is known about the weights of the underlying graph. Here the original upper bound on the expected running time by Neumann and Wegener [Theor. Comput. Sci. 378(1), 32-40, 2007], which...

  5. Differential expression of the Bombyx mori diapause-termination timer gene Ea4 in diapause-inducing temperature and photoperiod.

    Science.gov (United States)

    Xu, Li; Liang, Hui; Niu, Yanshan; Wang, Ying; Sima, Yanghu; Xu, Shiqing

    2012-03-01

    Diapause in Bombyx mori eggs is induced by temperature and photoperiod at the stage of embryonic development in the maternal generation. In those diapause eggs, Esterase-A4 is suggested to serve as a diapause-termination timer (TIME-EA4), because its ATPase activity shows an interval-timer elevation after acid treatment or chilling of eggs to break diapause. To clarify whether the timed ATPase activity of TIME-EA4 is related to its gene (Ea4) expression, we analyzed Ea4 mRNA of eggs in diapause-inducing environmental conditions. Reverse transcription PCR (RT-PCR) analysis showed that the level of Ea4 mRNA was lower in 15DD than in 25LL (P 0.05). Furthermore, expressed sequence tag profile and gene microarray analysis demonstrated that Ea4 showed stage-specific and tissue-specific expression during postembryonic stages, high Ea4 mRNA in the spinning and eclosion stages, and in integument and head, but low in gonads of fifth-instar day-3 larvae. Then we analyzed the relationship between TIME-EA4 ATPase activities and Ea4 gene expression. The ATPase activities in diapause eggs laid by the resultant adults transiently elevated after treatments to break diapause, that is, at 1.5 h after common-acid treatment and day 13 after chilling at 5°C. However, these elevations of enzyme activities were not accompanied by any increases in Ea4 mRNA levels. In conclusion, the termination of the Bombyx embryonic diapause is related to TIME-EA4 but not to its gene expression. © 2012 Wiley Periodicals, Inc.

  6. 75 FR 70011 - Guidance for Industry, Mammography Quality Standards Act Inspectors, and Food and Drug...

    Science.gov (United States)

    2010-11-16

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry, Mammography Quality Standards Act Inspectors, and Food and Drug Administration Staff; The Mammography Quality Standards Act Final Regulations: Modifications and Additions to Policy Guidance Help System 13; Availability AGENCY: Food and Drug...

  7. Project Closeout: Guidance for Final Evaluation of Building America Communities

    Energy Technology Data Exchange (ETDEWEB)

    Norton, P.; Burch, J.; Hendron, B.

    2008-03-01

    This report presents guidelines for Project Closeout. It is used to determine whether the Building America program is successfully facilitating improved design and practices to achieve energy savings goals in production homes. Its objective is to use energy simulations, targeted utility bill analysis, and feedback from project stakeholders to evaluate the performance of occupied BA communities.

  8. 77 FR 74194 - Issuance of Final Guidance Publication

    Science.gov (United States)

    2012-12-13

    ... entitled ``Preventing Occupational Respiratory Disease from Exposures Caused by Dampness in Office...: National Institute for Occupational Safety and Health (NIOSH) of the Centers for Disease Control and... Occupational Safety and Health, Centers for Disease Control and Prevention. BILLING CODE 4163-19-P...

  9. Optimal sliding guidance algorithm for Mars powered descent phase

    Science.gov (United States)

    Wibben, Daniel R.; Furfaro, Roberto

    2016-02-01

    Landing on large planetary bodies (e.g. Mars) with pinpoint accuracy presents a set of new challenges that must be addressed. One such challenge is the development of new guidance algorithms that exhibit a higher degree of robustness and flexibility. In this paper, the Zero-Effort-Miss/Zero-Effort-Velocity (ZEM/ZEV) optimal sliding guidance (OSG) scheme is applied to the Mars powered descent phase. This guidance algorithm has been specifically designed to combine techniques from both optimal and sliding control theories to generate an acceleration command based purely on the current estimated spacecraft state and desired final target state. Consequently, OSG yields closed-loop trajectories that do not need a reference trajectory. The guidance algorithm has its roots in the generalized ZEM/ZEV feedback guidance and its mathematical equations are naturally derived by defining a non-linear sliding surface as a function of the terms Zero-Effort-Miss and Zero-Effort-Velocity. With the addition of the sliding mode and using Lyapunov theory for non-autonomous systems, one can formally prove that the developed OSG law is globally finite-time stable to unknown but bounded perturbations. Here, the focus is on comparing the generalized ZEM/ZEV feedback guidance with the OSG law to explicitly demonstrate the benefits of the sliding mode augmentation. Results show that the sliding guidance provides a more robust solution in off-nominal scenarios while providing similar fuel consumption when compared to the non-sliding guidance command. Further, a Monte Carlo analysis is performed to examine the performance of the OSG law under perturbed conditions.

  10. Quality in career guidance: The Danish case

    DEFF Research Database (Denmark)

    Plant, Peter

    2011-01-01

    Quality assurance systems are introduced in career guidance to monitor, control and develop guidance interventions. The Danish case represents at centrally driven, top-down approach......Quality assurance systems are introduced in career guidance to monitor, control and develop guidance interventions. The Danish case represents at centrally driven, top-down approach...

  11. Current Trends in Tactical Missile Guidance

    Directory of Open Access Journals (Sweden)

    S. Vathsal

    2005-07-01

    Full Text Available The problem of tactical missile guidance is very challenging and has been treated using several basic metlfodologies in the past four decades. Major techniques can be grouped underclassical guidance laws, modern guidance laws, l'aws for manoeuvring targets, predictive guidance for endgame scenario, and guidance laws based on intelligent control methods. Each technique has some advantages and disadvantages while implementing in a practical system. Guidance law selection is dictated by nature of flight profile like boost, midcourse, terminal homing, etc, and also miss-distance and a single-shot kill probability. This paper presents a brief survey of the existing techniques and current trends in tactical missile guidance.

  12. Impact Time Guidance Law Considering Autopilot Dynamics Based on Variable Coefficients Strategy for Maneuvering Target

    Directory of Open Access Journals (Sweden)

    Wei Shang

    2015-01-01

    Full Text Available This paper investigates the terminal guidance problem for the missile intercepting a maneuvering target with impact time constraint. An impact time guidance law based on finite time convergence control theory is developed regarding the target motion as an unknown disturbance. To further improve the performance of the guidance law, an autopilot dynamics which is considered as a first-order lag is taken into consideration. In the proposed method, the coefficients change with the relative distance between missile and target. This variable coefficient strategy ensures that the missile impacts the target at the desired time with little final miss distance. Then it is proved that states of the guidance system converge to sliding mode in finite time under the proposed guidance law. Numerical simulations are presented to demonstrate the effectiveness of the impact time guidance law with autopilot dynamics (ITGAD.

  13. Information architecture. Volume 3: Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-04-01

    The purpose of this document, as presented in Volume 1, The Foundations, is to assist the Department of Energy (DOE) in developing and promulgating information architecture guidance. This guidance is aimed at increasing the development of information architecture as a Departmentwide management best practice. This document describes departmental information architecture principles and minimum design characteristics for systems and infrastructures within the DOE Information Architecture Conceptual Model, and establishes a Departmentwide standards-based architecture program. The publication of this document fulfills the commitment to address guiding principles, promote standard architectural practices, and provide technical guidance. This document guides the transition from the baseline or defacto Departmental architecture through approved information management program plans and budgets to the future vision architecture. This document also represents another major step toward establishing a well-organized, logical foundation for the DOE information architecture.

  14. Autonomous Guidance, Navigation and Control

    Science.gov (United States)

    Bordano, A. J.; Mcswain, G. G.; Fernandes, S. T.

    1991-01-01

    The NASA Autonomous Guidance, Navigation and Control (GN&C) Bridging program is reviewed to demonstrate the program plan and GN&C systems for the Space Shuttle. The ascent CN&C system is described in terms of elements such as the general-purpose digital computers, sensors for the navigation subsystem, the guidance-system software, and the flight-control subsystem. Balloon-based and lidar wind soundings are used for operations assessment on the day of launch, and the guidance software is based on dedicated units for atmospheric powered flight, vacuum powered flight, and abort-specific situations. Optimization of the flight trajectories is discussed, and flight-control responses are illustrated for wavelengths of 500-6000 m. Alternate sensors are used for load relief, and adaptive GN&C systems based on alternate gain synthesis are used for systems failures.

  15. Guidance on Radiochronometry

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Ross W. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Gaffney, Amy M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kristo, Michael J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-08-21

    Radiochronometry is the measurement of radioactive materials and their decay products to determine the “age” of the material. It differs from the practice of geochronology in that the materials (samples) are man-made, and in that the timespan of interest is confined to the nuclear era, i.e., since the discovery of fission in 1939. In radiochronometry, the “age” of the material ideally records the time when the sample was manufactured, or produced in the final form that is analyzed in the laboratory. It is an important predictive signature in a nuclear forensic investigation which can help in the attribution to a source. The calculation of this “age” can only be made if a model is invoked that allows simplification of the parent radionuclide to daughter isotope decay equation. The simplification required for this model is that the parent was purified completely from all traces of its daughter product at the time of sample preparation. Then, this “age” should be described as the “model age” from which a “model date” in the past can then be calculated. For this model date to represent the date of sample preparation, two other assumptions are required to be true. The first is that the material has remained a closed system since that time (i.e., that there has been no loss or gain of either parent or daughter), and the second is that the analyses are accurate.

  16. 78 FR 28873 - Availability of Final Environmental Assessment and Finding of No Significant Impact for the...

    Science.gov (United States)

    2013-05-16

    ... of availability. SUMMARY: This notice announces the availability of a Final Environmental Assessment (Final EA) which examines the reasonably foreseeable environmental impacts and socio-economic impacts of... SECURITY Coast Guard Availability of Final Environmental Assessment and Finding of No Significant...

  17. Agent Based Individual Traffic guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen Bundgaard

    2004-01-01

    When working with traffic planning or guidance it is common practice to view the vehicles as a combined mass. >From this models are employed to specify the vehicle supply and demand for each region. As the models are complex and the calculations are equally demanding the regions and the detail...... can be obtained through cellular phone tracking or GPS systems. This information can then be used to provide individual traffic guidance as opposed to the mass information systems of today -- dynamic roadsigns and trafficradio. The goal is to achieve better usage of road and time. The main topic...

  18. The e/a criterion of Zr-based bulk metallic glasses

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Y.M.; Xu, W.P.; Qiang, J.B.; Wong, C.H.; Shek, C.H.; Dong, C

    2004-07-15

    Bulk metallic glasses (BMGs) have been found in many Zr-based multi-component alloys. After discussions on the diffraction characteristics corresponding to the Fermi surfaces-Brillouin zone interaction effect in the Zr-based BMG-related phases, we point out that the 2k{sub f}{approx}k{sub p} rule is satisfied when the conduction electron concentration of Zr is 1.5. These BMG- and quasicrystal-related phases, sharing nearly the same conduction electron concentrations per atom (e/a), are e/a-constant phases in a given alloy system. Such an e/a-based criterion is then applied to the Zr-Al-Ni system and a series of BMGs with constant e/a ratio, equal to 1.5, are obtained by suction casting.

  19. Strength Pareto particle swarm optimization and hybrid EA-PSO for multi-objective optimization.

    Science.gov (United States)

    Elhossini, Ahmed; Areibi, Shawki; Dony, Robert

    2010-01-01

    This paper proposes an efficient particle swarm optimization (PSO) technique that can handle multi-objective optimization problems. It is based on the strength Pareto approach originally used in evolutionary algorithms (EA). The proposed modified particle swarm algorithm is used to build three hybrid EA-PSO algorithms to solve different multi-objective optimization problems. This algorithm and its hybrid forms are tested using seven benchmarks from the literature and the results are compared to the strength Pareto evolutionary algorithm (SPEA2) and a competitive multi-objective PSO using several metrics. The proposed algorithm shows a slower convergence, compared to the other algorithms, but requires less CPU time. Combining PSO and evolutionary algorithms leads to superior hybrid algorithms that outperform SPEA2, the competitive multi-objective PSO (MO-PSO), and the proposed strength Pareto PSO based on different metrics.

  20. MMAS Versus Population-Based EA on a Family of Dynamic Fitness Functions

    DEFF Research Database (Denmark)

    Lissovoi, Andrei; Witt, Carsten

    2015-01-01

    that a (2+1) EA with genotype diversity is able to find the global optimum of the Maze function, previously considered by Kötzing and Molter [9], in polynomial time. This is then generalized to a hierarchy result stating that for every μ , a ( μ +1) EA with genotype diversity is able to track a Maze...... function extended over a finite alphabet of μ symbols, whereas population size μ−1 is not sufficient. Furthermore, we show that MMAS does not require additional modifications to track the optimum of the finite-alphabet Maze functions, and, using a novel drift statement to simplify the analysis, reduce...... the required phase length of the Maze function....

  1. The adiabatic electron affinities (EAs) for the heteroatomic molecule SO 4: An MP2/CBS study

    Science.gov (United States)

    Zheng, Wenxu; Lau, Kai-Chung; Wong, Ning-Bew; Li, Wai-Kee

    2009-01-01

    An MP2/CBS approach has been proposed to calculate the adiabatic electron affinities (EAs) for the heteroatomic molecule SO 4. The method involves the approximation to the complete basis set (CBS) limit at the MP2 level. The zero-point vibrational energy correction, the diagonal Born-Oppenheimer correction, and the scalar relativistic effect correction have been also made in the calculations. The present MP2/CBS predictions are found to be in good accord with the available experimental values.

  2. The Dependence of the Age Parameter from EAS Size and Zenith Angle of Incidence

    CERN Document Server

    Chilingarian, A A; Kazarian, S; Hovsepyan, G G; Mamidjanyan, E A; Melkumyan, L G; Sokhoyan, S H

    2000-01-01

    The quality of the MAKET-ANI detector installation in view of the uniformityof the registration efficiency is demonstrated. Based on a data samplecollected by the MAKET-ANI array in the period of June 1997 - March 1999, thedependencies of the age parameter on the zenith angle and the EAS size(10^5-10^7) are studied. The variation of the age parameter with the showersize can be approximately related to the elongation rate.

  3. Molecular heterogeneity of TIME-EA4, a timer protein in silkworm diapause eggs.

    Science.gov (United States)

    Pitchayawasin-Thapphasaraphong, Suthasinee; Tani, Naoki; Isobe, Minoru; Kai, Hidenori; Kurahashi, Takuya; Kato, Junko; Trisunan, Saikwan

    2009-07-01

    TIME-EA4 is an ATPase that measures time intervals as a diapause-duration clock found in diapause eggs of the silkworm, Bombyx mori. In the current studies, we report the molecular heterogeneity of TIME-EA4 protein regarding not only amino acid L62V, but also the numbers and linkage patterns of the sugar chain attached to the Asn(22) residue. These sugar chain structures were determined in a pico-molar amount of the protein by combining the methods of chemical modification (Smith degradation) and nano-HPLC-electrospray ionization-quadrupole-time of fight-mass spectrometry (ESI-Q-TOF-MS) and -MS/MS. The Japanese and bi-voltine Thai silkworm strains were compared to show the heterogeneity represented by four kinds of molecular species. Judicious choice of the combination methods led us to find the first example of a linkage-position difference in the glycosidic bonds even in sugar moieties of the same molecular weight; thus, the Man(1-6)Man(1-4)GlcNAc(1-4)GlcNAc structure in the C108 pure strain and Man(1-3)Man(1-4)GlcNAc(1-4)GlcNAc structure in the Kinshu-Showa hybrid. A total of five kinds of molecular heterogeneity was determined, including the amino acids in TIME-EA4 protein. This paper describes the details for determining the sugar chain linkage in TIME-EA4 from the diapause eggs of various silkworm strains.

  4. 47 CFR 90.763 - EA, Regional and nationwide system operations.

    Science.gov (United States)

    2010-10-01

    ... on a case-by-case basis upon submission by the EA or Regional licensee of: (A) A technical analysis... using the F(50,50) field strength chart for Channels 7-13 in § 73.699 (Fig. 10) of this chapter, with a... F(50,10) field strength chart for Channels 7-13 in § 73.699 (Fig. 10a) of this chapter, with a 9 dB...

  5. Proton-pion and two-pion correlations in eA interactions

    Energy Technology Data Exchange (ETDEWEB)

    Degtyarenko, P.V. [ITEP, Moscow (Russian Federation); Doroshkevich, E.A. [ITEP, Moscow (Russian Federation); Kurzenkov, A.A. [ITEP, Moscow (Russian Federation); Leksin, G.A. [ITEP, Moscow (Russian Federation); Stavinsky, A.V. [ITEP, Moscow (Russian Federation); Vlassov, A.V. [ITEP, Moscow (Russian Federation)

    1997-05-01

    We report here the results on studying of proton-pion and two-pion correlations in eA interactions at 5 GeV. Kinematic correlations were studied as a function of the two-particle opening angle, their momenta and proton multiplicity. The universal properties of correlation functions were found with respect to different particle species. Interferometry method was used to determine the size of the interaction region. (orig.). With 2 figs.

  6. TobEA: an atlas of tobacco gene expression from seed to senescence

    Directory of Open Access Journals (Sweden)

    Mueller Lukas A

    2010-02-01

    Full Text Available Abstract Background Transcriptomics has resulted in the development of large data sets and tools for the progression of functional genomics and systems biology in many model organisms. Currently there is no commercially available microarray to allow such expression studies in Nicotiana tabacum (tobacco. Results A custom designed Affymetrix tobacco expression microarray was generated from a set of over 40k unigenes and used to measure gene expression in 19 different tobacco samples to produce the Tobacco Expression Atlas (TobEA. TobEA provides a snap shot of the transcriptional activity for thousands of tobacco genes in different tissues throughout the lifecycle of the plant and enables the identification of the biological processes occurring in these different tissues. 772 of 2513 transcription factors previously identified in tobacco were mapped to the array, with 87% of them being expressed in at least one tissue in the atlas. Putative transcriptional networks were identified based on the co-expression of these transcription factors. Several interactions in a floral identity transcription factor network were consistent with previous results from other plant species. To broaden access and maximise the benefit of TobEA a set of tools were developed to provide researchers with expression information on their genes of interest via the Solanaceae Genomics Network (SGN web site. The array has also been made available for public use via the Nottingham Arabidopsis Stock Centre microarray service. Conclusions The generation of a tobacco expression microarray is an important development for research in this model plant. The data provided by TobEA represents a valuable resource for plant functional genomics and systems biology research and can be used to identify gene targets for both fundamental and applied scientific applications in tobacco.

  7. Guidance for evidence-informed policies about health systems: rationale for and challenges of guidance development.

    Science.gov (United States)

    Bosch-Capblanch, Xavier; Lavis, John N; Lewin, Simon; Atun, Rifat; Røttingen, John-Arne; Dröschel, Daniel; Beck, Lise; Abalos, Edgardo; El-Jardali, Fadi; Gilson, Lucy; Oliver, Sandy; Wyss, Kaspar; Tugwell, Peter; Kulier, Regina; Pang, Tikki; Haines, Andy

    2012-01-01

    In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the challenges to developing such guidance.

  8. 78 FR 56752 - Interim Staff Guidance Specific Environmental Guidance for Integral Pressurized Water Reactors...

    Science.gov (United States)

    2013-09-13

    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Interim Staff Guidance Specific Environmental Guidance for Integral Pressurized Water Reactors... and operate integral pressurized water reactors (iPWR). This guidance applies to environmental reviews...

  9. A novel plasmid pEA68 of Erwinia amylovora and the description of a new family of plasmids.

    Science.gov (United States)

    Ismail, Emadeldeen; Blom, Jochen; Bultreys, Alain; Ivanović, Milan; Obradović, Aleksa; van Doorn, Joop; Bergsma-Vlami, Maria; Maes, Martine; Willems, Anne; Duffy, Brion; Stockwell, Virginia O; Smits, Theo H M; Puławska, Joanna

    2014-12-01

    Recent genome analysis of Erwinia amylovora, the causal agent of fire blight disease on Rosaceae, has shown that the chromosome is highly conserved among strains and that plasmids are the principal source of genomic diversity. A new circular plasmid, pEA68, was found in E. amylovora strain 692 (LMG 28361), isolated in Poland from Sorbus (mountain ash) with fire blight symptoms. Annotation of the 68,763-bp IncFIIa-type plasmid revealed that it contains 79 predicted CDS, among which two operons (tra, pil) are associated with mobility. The plasmid is maintained stably in E. amylovora and does not possess genes associated with antibiotic resistance or known virulence genes. Curing E. amylovora strain 692 of pEA68 did not influence its virulence in apple shoots nor amylovoran synthesis. Of 488 strains of E. amylovora from seventeen countries, pEA68 was only found in two additional strains from Belgium. Although the spread of pEA68 is currently limited to Europe, pEA68 comprises, together with pEA72 and pEA78 both found in North America, a new plasmid family that spans two continents.

  10. EA/G-GA for Single Machine Scheduling Problems with Earliness/Tardiness Costs

    Directory of Open Access Journals (Sweden)

    Yuh-Min Chen

    2011-06-01

    Full Text Available An Estimation of Distribution Algorithm (EDA, which depends on explicitly sampling mechanisms based on probabilistic models with information extracted from the parental solutions to generate new solutions, has constituted one of the major research areas in the field of evolutionary computation. The fact that no genetic operators are used in EDAs is a major characteristic differentiating EDAs from other genetic algorithms (GAs. This advantage, however, could lead to premature convergence of EDAs as the probabilistic models are no longer generating diversified solutions. In our previous research [1], we have presented the evidences that EDAs suffer from the drawback of premature convergency, thus several important guidelines are provided for the design of effective EDAs. In this paper, we validated one guideline for incorporating other meta-heuristics into the EDAs. An algorithm named “EA/G-GA” is proposed by selecting a well-known EDA, EA/G, to work with GAs. The proposed algorithm was tested on the NP-Hard single machine scheduling problems with the total weighted earliness/tardiness cost in a just-in-time environment. The experimental results indicated that the EA/G-GA outperforms the compared algorithms statistically significantly across different stopping criteria and demonstrated the robustness of the proposed algorithm. Consequently, this paper is of interest and importance in the field of EDAs.

  11. Galvanotactic migration of EA.Hy926 endothelial cells in a novel designed electric field bioreactor.

    Science.gov (United States)

    Long, Haiyan; Yang, Gang; Wang, Zhengrong

    2011-12-01

    Endogenous direct current electric fields (dcEFs) play a significant role in major biological processes such as embryogenesis, wound healing, and tissue regeneration. In this study, the galvanotaxis of human umbilical vein endothelial cell line EA.Hy926 was investigated by using a novel designed bioreactor. The physical features of the bioreactor were discussed and analyzed by both numerical simulation method and equivalent circuit model method. EA.Hy926 cells were cultured in the bioreactor for 10-24 h under 50-250 mV/mm dcEFs. Cell migration direction, distance, and velocity were recorded under an online time-lapse microscope. The effects of serum and growth factor on cell galvanotatic migration were investigated. To further explore the role of dcEFs in regulating endothelial cells, we analyzed the endothelial cell proliferation and secretion of nitric oxide (NO), endothelin-1 (ET-1) in response to dcEFs of physiological strength. Our results showed that EA.Hy926 cells had an obvious directional migration to the cathode, and the EF-directed migration was voltage dependent. The results also showed dcEFs did not affect cell proliferation, but affected the productions of NO and ET-1. Our study also showed the novel bioreactor, with a compact and planar style, makes it more convenient and more reasonable for EF stimulation experiments than earlier chamber designs.

  12. Guidance Compliance Behavior on VMS Based on SOAR Cognitive Architecture

    Directory of Open Access Journals (Sweden)

    Shiquan Zhong

    2012-01-01

    Full Text Available SOAR is a cognitive architecture named from state, operator and result, which is adopted to portray the drivers' guidance compliance behavior on variable message sign (VMS in this paper. VMS represents traffic conditions to drivers by three colors: red, yellow, and green. Based on the multiagent platform, SOAR is introduced to design the agent with the detailed description of the working memory, long-term memory, decision cycle, and learning mechanism. With the fixed decision cycle, agent transforms state through four kinds of operators, including choosing route directly, changing the driving goal, changing the temper of driver, and changing the road condition of prediction. The agent learns from the process of state transformation by chunking and reinforcement learning. Finally, computerized simulation program is used to study the guidance compliance behavior. Experiments are simulated many times under given simulation network and conditions. The result, including the comparison between guidance and no guidance, the state transition times, and average chunking times are analyzed to further study the laws of guidance compliance and learning mechanism.

  13. Atmospheric guidance techniques and performance

    Science.gov (United States)

    Harpold, J. C.; Gavert, D. E.

    1982-01-01

    The Orbiter entry guidance system controls the Space Shuttle Orbiter from the initial atmospheric penetration point to the point at which an earth relative velocity of 2500 feet/second is reached. At the latter point, control of the Orbiter is transferred to the terminal area energy management system. The entry guidance system is based on the concept that the range to be flown during entry is a unique function of the drag deceleration profile flown throughout the entry. The range prediction during entry is based on analytic equations which are simple drag deceleration functions of earth relative velocity above Mach 10.5 and energy with respect to the earth below Mach 10.5. Flight through the entry corridor is accomplished by linking these simple drag deceleration functions together in series in order to define a drag deceleration reference profile. The results of the first three Space Shuttle missions have not only verified the entry guidance concept but have also demonstrated the stability of the guidance system.

  14. Abortion Information: A Guidance Viewpoint

    Science.gov (United States)

    Wolleat, Patricia L.

    1975-01-01

    A number of questions relating to providing abortion information to teenagers can be raised from legal, ethical and philosophical standpoints. The purpose of this article is to examine abortion information-giving from the perspective of counseling and guidance theory and practice. (Author)

  15. Teacher Guidance of Knowledge Construction

    Science.gov (United States)

    Schwarz, Baruch; Dreyfus, Tommy; Hadas, Nurit; Hershkowitz, Rina

    2004-01-01

    This paper focuses on how teachers guide construction of knowledge in classrooms. We suggest that guidance hinges on the kind of dialogue teachers choose to engage students in. We propose several classroom dialogue types relevant for the construction of knowledge and suggest that critical dialogue is particularly effective for knowledge…

  16. Guidance: Interim Municipal Settlement Policy

    Science.gov (United States)

    Interim guidance and fact sheets regarding settlements involving municipalities or municipal waste under Section 122 CERCLA as amended by SARA. Interim policy sets forth the criteria by which EPA generally determines whether to exercise enforcement discretion to pursue MSW generators and transporters as PRPs.

  17. Agent Based Individual Traffic Guidance

    DEFF Research Database (Denmark)

    Wanscher, Jørgen

    This thesis investigates the possibilities in applying Operations Research (OR) to autonomous vehicular traffic. The explicit difference to most other research today is that we presume that an agent is present in every vehicle - hence Agent Based Individual Traffic guidance (ABIT). The next...

  18. DOE Waste Treatability Group Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Kirkpatrick, T.D.

    1995-01-01

    This guidance presents a method and definitions for aggregating U.S. Department of Energy (DOE) waste into streams and treatability groups based on characteristic parameters that influence waste management technology needs. Adaptable to all DOE waste types (i.e., radioactive waste, hazardous waste, mixed waste, sanitary waste), the guidance establishes categories and definitions that reflect variations within the radiological, matrix (e.g., bulk physical/chemical form), and regulated contaminant characteristics of DOE waste. Beginning at the waste container level, the guidance presents a logical approach to implementing the characteristic parameter categories as part of the basis for defining waste streams and as the sole basis for assigning streams to treatability groups. Implementation of this guidance at each DOE site will facilitate the development of technically defined, site-specific waste stream data sets to support waste management planning and reporting activities. Consistent implementation at all of the sites will enable aggregation of the site-specific waste stream data sets into comparable national data sets to support these activities at a DOE complex-wide level.

  19. Interstitial guidance of cancer invasion.

    NARCIS (Netherlands)

    Gritsenko, P.G.; Ilina, O.; Friedl, P.H.

    2012-01-01

    Cancer cell invasion into healthy tissues develops preferentially along pre-existing tracks of least resistance, followed by secondary tissue remodelling and destruction. The tissue scaffolds supporting or preventing guidance of invasion vary in structure and molecular composition between organs. In

  20. Final Environmental Assessment (EA) Addressing the Repair of Runway 05/23 at Fairchild Air Force Base, Washington

    Science.gov (United States)

    2009-11-01

    between the United States, Canada, Japan, Mexico , and the former Soviet Union for the protection of migratory birds. Unless otherwise permitted by...government’s compliance with its treaty obligations to Canada, Mexico , Russia, and Japan. EO 13186 provides broad guidelines on conservation responsibilities... IVA 99001 0¢M Mr. Brantli!n. llmnk you for your commc:nts pm\\’idcd on dte Drufl Em•iromuenwl .·lss’-’·\\’~’IW!III .-l<ldrt:s~·lng lite Rt~puir of

  1. Final Environmental Assessment (EA), Long-Term Integrated Management of Mission-Generated Solid Waste, Edwards Air Force Base, California

    Science.gov (United States)

    2016-11-28

    behind the hospital and resulted mainly from a continuous noise from an air conditioning system on the roof of the hospital ; • From 57 to 65 dB on...surrounding communities within the Antelope Valley. Major industries in the area include agriculture, mining, and tourism , in addition to aerospace...sensitive receptors, such as schools, hospitals or residential areas to substantial pollutant concentrations Since there are no sensitive receptors within

  2. Final Technical Report for Collaborative Research: CRI-EaSM Multiscale Modeling Aerosol Indirect Effects on Decadal Timescales

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sungsu [National Center for Atmospheric Research (NCAR), Boulder, CO (United States)

    2015-11-29

    Originally, the main role of the P.I. (Sungsu Park) in this project was to improve the treatment of cloud microphysics in the CAM5 shallow and deep convection scheme. During the progress of the project, however, the main research theme was changed to develop a new unified convection scheme (so called, UNICON) with the permission of the program manager.

  3. Cooperative Guidance for Multimissile Salvo Attack

    Institute of Scientific and Technical Information of China (English)

    Zhao Shiyu; Zhou Rui

    2008-01-01

    Cooperative guidance problems of multiple missiles are considered in this article. A cooperative guidance scheme, where coordi-nation algorithms and local guidance laws are combined together, is proposed. This scheme actually builds up a hierarchical cooperative guidance architecture, which may provide a general solution to the multimissile cooperative guidance problems. In the case of salvo attacks which require missiles to hit the target simultaneously, both centralized and distributed coordination algorithms are derived based on the impact-time-control guidance (ITCG) law. Numerical simulations are performed to demonstrate the effectiveness of the proposed approaches.

  4. Characterization of Coal Tar Pitch and Paving Pitch by UV, EA and NMR%Characterization of Coal Tar Pitch and Paving Pitch by UV,EA and NMR

    Institute of Scientific and Technical Information of China (English)

    XIAO Yan-hua; FENG Rui-jie; CAO Su-mei; LIU Xiang-yong; GAO Ting; PAN Zhi-quan

    2011-01-01

    In order to enlarge the use of coal tar pitch(CTP) in paving road, CTP and 60th paving pitch (PP) were extracted by n-heptane, toluene and ethanol step by step in a Soxhlet apparatus. The three fractions of CTP and PP were detected using UV-absorption(UV-A) ,elemental analyses(EA) and nuclear magnetic resonance (NMR) firstly as a whole unit after quality characterization of physical nature of CTP and PP were finished. The CTP had more saturate aliphatie and residue compounds dissolved in ethanol. On the other hand there were more continental type structures of aromatic ring than that of PP. There was almost no residue in PP after extracted by ethanol. The results explained why CTP was crisp in cold winter and was soften in summer. The following research will focus on how to change the chemical construction of CTP into the relative similar structures with those of PP through adding polymer.

  5. Technical guidance for siting criteria development

    Energy Technology Data Exchange (ETDEWEB)

    Aldrich, D.C.; Sprung, J.L.; Alpert, D.J.; Diegert, K.; Ostmeyer, R.M.; Ritchie, L.T.; Strip, D.R.; Johnson, J.D.; Hansen, K.; Robinson, J.

    1982-12-01

    Technical guidance to support the formulation and comparison of possible siting criteria for nuclear power plants has been developed in four areas: (1) consequences of hypothetical severe nuclear-power-plant accidents, (2) characteristics of population distributions about current reactor sites, (3) site availability within the continental United States, and (4) socioeconomic impacts of reactor siting. The impact on consequences of source-term magnitude, meteorology, population distribution, and emergency response have been analyzed. Population distributions about current sites were analyzed to identify statistical characteristics, time trends, and regional differences. A site-availability data bank was constructed for the continential United States. The data bank contains information about population densities, seismicity, topography, water availability, and land-use restrictions. Finally, the socioeconomic impacts of rural-industrialization projects, energy boomtowns, and nuclear power plants were examined to determine their nature, magnitude, and dependence on site demography and remoteness.

  6. δ15N measurement of organic and inorganic substances by EA-IRMS: a speciation-dependent procedure.

    Science.gov (United States)

    Gentile, Natacha; Rossi, Michel J; Delémont, Olivier; Siegwolf, Rolf T W

    2013-01-01

    Little attention has been paid so far to the influence of the chemical nature of the substance when measuring δ(15)N by elemental analysis (EA)-isotope ratio mass spectrometry (IRMS). Although the bulk nitrogen isotope analysis of organic material is not to be questioned, literature from different disciplines using IRMS provides hints that the quantitative conversion of nitrate into nitrogen presents difficulties. We observed abnormal series of δ(15)N values of laboratory standards and nitrates. These unexpected results were shown to be related to the tailing of the nitrogen peak of nitrate-containing compounds. A series of experiments were set up to investigate the cause of this phenomenon, using ammonium nitrate (NH(4)NO(3)) and potassium nitrate (KNO(3)) samples, two organic laboratory standards as well as the international secondary reference materials IAEA-N1, IAEA-N2-two ammonium sulphates [(NH(4))(2)SO(4)]-and IAEA-NO-3, a potassium nitrate. In experiment 1, we used graphite and vanadium pentoxide (V(2)O(5)) as additives to observe if they could enhance the decomposition (combustion) of nitrates. In experiment 2, we tested another elemental analyser configuration including an additional section of reduced copper in order to see whether or not the tailing could originate from an incomplete reduction process. Finally, we modified several parameters of the method and observed their influence on the peak shape, δ(15)N value and nitrogen content in weight percent of nitrogen of the target substances. We found the best results using mere thermal decomposition in helium, under exclusion of any oxygen. We show that the analytical procedure used for organic samples should not be used for nitrates because of their different chemical nature. We present the best performance given one set of sample introduction parameters for the analysis of nitrates, as well as for the ammonium sulphate IAEA-N1 and IAEA-N2 reference materials. We discuss these results considering the

  7. Recent results from Yakutsk experiment: development of EAS, energy spectrum and primary particle mass composition in the energy region of 10^15-10^19 eV

    CERN Document Server

    Knurenko, S P; Pravdin, M I; Sabourov, A V; Sleptsov, I Ye

    2006-01-01

    Experimental data obtained at the Yakutsk array after the modernization in 1993 are analyzed. The characteristics of EAS longitudinal and radial development found from the charged particle flux and EAS Cherenkov light registered at the Yakutsk complex array are presented. The energy spectrum of EAS obtained from Cherenkov light and an estimate of the PCR mass composition are presented.

  8. Career guidance and counselling for mobilities

    National Research Council Canada - National Science Library

    Zvariková, Mária

    2011-01-01

    In its first part, the article provides a basic overview on guidance and counselling for mobility issues at universities, focusing on the possibilities and role of guidance and counselling for both...

  9. A guidance concept for hypersonic aerospacecrafts

    Science.gov (United States)

    Ishimoto, Shinji

    In this paper a guidance concept for hypersonic re-entry flights is presented. The method uses a closed-form guidance technique based on a drag acceleration reference profile. A guidance law for range control is developed. It employs a physical relation between vehicle energy and range instead of a prediction-correction technique used for Shuttle entry guidance. Simulation results show that the algorithm provides good performance.

  10. 85 km Long Reach PON System Using a Reflective SOA-EA Modulator and Distributed Raman Fiber Amplification

    DEFF Research Database (Denmark)

    Tafur Monroy, Idelfonso; Öhman, Filip; Yvind, Kresten

    2006-01-01

    We report on a bidirectional 85 km long reach PON system supported by distributed fiber Raman amplification with a record 7.5 Gb/s remote carrier modulated upstream signal by employing a reflective SOA-EA monolithically integrated circuit......We report on a bidirectional 85 km long reach PON system supported by distributed fiber Raman amplification with a record 7.5 Gb/s remote carrier modulated upstream signal by employing a reflective SOA-EA monolithically integrated circuit...

  11. Report of the Regional Co-ordination Meeting for the North Sea and Eastern Arctic (RCM NS&EA) 2014

    OpenAIRE

    Armstrong, M.; van Beek, F; DALSKOV J.; Elliott, M; Elson, J.; Griuniene, V. (Vilda); M. Hansson; Janakakis, M. (Marta); Kjems-Nilsen, H. (Henrik); Knapp, A. (Amelie); Kunzlik, P. (Phil); Lorenzo-González, J. (José); Mahe, K (Kelig); Morgado, C.; Nimmegeers, S.

    2014-01-01

    Report of the Regional Co-ordination Meeting for the North Sea and Eastern Arctic (RCM NS&EA) 2014 Swedish University of Agriculture Sciences (SLU Aqua) Lysekil, Sweden 08-12 September 2014 The RCM NS&EA met in Lysekil (Sweden) between 8-12 September 2014. The main purpose of the RCM is coordinate the National Programmes (NP) of the Member States (MS) in the North Sea region for 2015.

  12. Quality Assurance in University Guidance Services

    Science.gov (United States)

    Simon, Alexandra

    2014-01-01

    In Europe there is no common quality assurance framework for the delivery of guidance in higher education. Using a case study approach in four university career guidance services in England, France and Spain, this article aims to study how quality is implemented in university career guidance services in terms of strategy, standards and models,…

  13. The Self in Guidance: Assumptions and Challenges.

    Science.gov (United States)

    Edwards, Richard; Payne, John

    1997-01-01

    Examines the assumptions of "self" made in the professional and managerial discourses of guidance. Suggests that these assumptions obstruct the capacity of guidance workers to explain their own practices. Drawing on contemporary debates over identity, modernity, and postmodernity, argues for a more explicit debate about the self in guidance. (RJM)

  14. 78 FR 53792 - Draft Guidance for Reciprocity

    Science.gov (United States)

    2013-08-30

    ...The U.S. Nuclear Regulatory Commission (NRC) is revising its licensing guidance for reciprocity. The NRC is requesting public comment on draft NUREG-1556, Volume 19, Revision 1, ``Consolidated Guidance about Materials Licenses: Guidance for Agreement State Licensees about NRC Form 241 `Report of Proposed Activities in Non- Agreement States, Areas of Exclusive Federal Jurisdiction, of Offshore......

  15. Providing Career Guidance for Young Women.

    Science.gov (United States)

    Colby, Pamela G.

    This module is directed at personnel working or planning to work in the areas of guidance, counseling, placement and follow-through in junior and senior high school settings, grades 7-12. The module topic is career guidance for young women of junior and senior high school age, aand the focus will be on providing nonbiased career guidance which…

  16. Quality Assurance in University Guidance Services

    Science.gov (United States)

    Simon, Alexandra

    2014-01-01

    In Europe there is no common quality assurance framework for the delivery of guidance in higher education. Using a case study approach in four university career guidance services in England, France and Spain, this article aims to study how quality is implemented in university career guidance services in terms of strategy, standards and models,…

  17. Reentry guidance for Space Shuttle

    Science.gov (United States)

    Causey, W.; Sohoni, V.

    1973-01-01

    An explicit guidance scheme is outlined which provides the appropriate energy management in order for the shuttle orbiter to reach any location within the required footprint. Considering the orbiter as entering the earth's atmosphere, expressions for the downrange, crossrange, and the time of the termination of the entry phase as functions of the control variables are developed. Performing an order-of-magnitude analysis of the terms in these expressions, only dominant terms are retained. Analytical expressions for the elements of the sensitivity matrix which represents the partial derivatives of the desired range with respect to control variables are formulated. Using the Gauss-Jordan inversion technique, the required change in guidance commands as a function of the deviations in the downrange and crossrange are explicitly computed.

  18. Reentry guidance for Space Shuttle

    Science.gov (United States)

    Causey, W.; Sohoni, V.

    1973-01-01

    An explicit guidance scheme is outlined which provides the appropriate energy management in order for the shuttle orbiter to reach any location within the required footprint. Considering the orbiter as entering the earth's atmosphere, expressions for the downrange, crossrange, and the time of the termination of the entry phase as functions of the control variables are developed. Performing an order-of-magnitude analysis of the terms in these expressions, only dominant terms are retained. Analytical expressions for the elements of the sensitivity matrix which represents the partial derivatives of the desired range with respect to control variables are formulated. Using the Gauss-Jordan inversion technique, the required change in guidance commands as a function of the deviations in the downrange and crossrange are explicitly computed.

  19. Review of soil contamination guidance

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, M.A.; Kennedy, W.E. Jr.; Soldat, J.K.

    1981-08-01

    A review of existing and proposed radioactive soil contamination standards and guidance was conducted for United Nuclear Corporation (UNC), Office of Surplus Facilities Management. Information was obtained from both government agencies and other sources during a literature survey. The more applicable standards were reviewed, evaluated, and summarized. Information pertaining to soil contamination for both facility operation and facility decommissioning was obtained from a variety of sources. These sources included: the Code of Federal Regulations, regulatory guides, the Federal Register, topical reports written by various government agencies, topical reports written by national laboratories, and publications from the American National Standards Institute (ANSI). It was difficult to directly compare the standards and guidance obtained from these sources since each was intended for a specific situation and different units or bases were used. However, most of the information reviewed was consistent with the philosophy of maintaining exposures at levels as low as reasonably achievable (ALARA).

  20. Teleautonomous guidance for mobile robots

    Science.gov (United States)

    Borenstein, J.; Koren, Y.

    1990-01-01

    Teleautonomous guidance (TG), a technique for the remote guidance of fast mobile robots, has been developed and implemented. With TG, the mobile robot follows the general direction prescribed by an operator. However, if the robot encounters an obstacle, it autonomously avoids collision with that obstacle while trying to match the prescribed direction as closely as possible. This type of shared control is completely transparent and transfers control between teleoperation and autonomous obstacle avoidance gradually. TG allows the operator to steer vehicles and robots at high speeds and in cluttered environments, even without visual contact. TG is based on the virtual force field (VFF) method, which was developed earlier for autonomous obstacle avoidance. The VFF method is especially suited to the accommodation of inaccurate sensor data (such as that produced by ultrasonic sensors) and sensor fusion, and allows the mobile robot to travel quickly without stopping for obstacles.

  1. Microfluidic control of axonal guidance

    Science.gov (United States)

    Gu, Ling; Black, Bryan; Ordonez, Simon; Mondal, Argha; Jain, Ankur; Mohanty, Samarendra

    2014-10-01

    The precision of axonal pathfinding and the accurate formation of functional neural circuitry are crucial for an organism during development as well as during adult central and peripheral nerve regeneration. While chemical cues are believed to be primarily responsible for axonal pathfinding, we hypothesize that forces due to localized fluid flow may directly affect neuronal guidance during early organ development. Here, we report direct evidence of fluid flow influencing axonal migration, producing turning angles of up to 90°. Microfluidic flow simulations indicate that an axon may experience significant bending force due to cross-flow, which may contribute to the observed axonal turning. This method of flow-based guidance was successfully used to fasciculate one advancing axon onto another, showcasing the potential of this technique to be used for the formation of in vitro neuronal circuits.

  2. Application of MPVR and TL-VR with 64-row MDCT in neonates with congenital EA and distal TEF.

    Science.gov (United States)

    Wen, Yang; Peng, Yun; Zhai, Ren-You; Li, Ying-Zi

    2011-03-28

    To assess the application of multiple planar volume reconstruction (MPVR) and three-dimensional (3D) transparency lung volume rendering (TL-VR) with 64-row multidetector-row computed tomography (MDCT) in neonates with congenital esophageal atresia (EA) and distal tracheoesophageal fistula (TEF). Twenty neonates (17 boys, 3 girls) with EA and distal TEF at a mean age of 4.6 d (range 1-16 d) were enrolled in this study. A helical scan of 64-row MDCT was performed at the 64 mm × 0.625 mm collimation. EA and TEF were reconstructed with MPVR and TL-VR, respectively. Initial diagnosis of EA was made by chest radiography showing the inserted catheter in the proximal blind-ended esophageal pouch. Manifestations of MDCT images were compared with the findings at surgery. MDCT showed the proximal and distal esophageal pouches in 20 cases. No significant difference was observed in gaps between the proximal and distal esophageal pouches detected by MPVR and TL-VR. The lengths of gaps between the proximal and distal esophageal pouches detected by MPVR and TL-VR correlated well with the findings at surgery (R = 0.87, P VR images showed the orifice of TEF in 4 cases. EA and distal TEF can be reconstructed using MPVR and TL-VR of 64-row MDCT, which is a noninvasive technique to demonstrate the distal esophageal pouches and inter-pouch distance in neonates with EA and distal TEF.

  3. 2011 Army Strategic Planning Guidance

    Science.gov (United States)

    2011-03-25

    TESI ) of 22,000 Soldiers, the Army’s total force by the end of the mid-term period is programmed to be 520K (AC). We will achieve a more...dwell ratios, extending TESI authority to adequately man deploying units and sustain the All-Volunteer Force, right-sizing the generating force, and... TESI Temporary End-Strength Increase WMD Weapons of Mass Destruction 2011 ARMY STRATEGIC PLANNING GUIDANCE Page 19 2011

  4. Current materiality guidance for auditors

    OpenAIRE

    McKee, Thomas E.; Eilifsen, Aasmund

    2000-01-01

    Auditors have to make materiality judgments on every audit. This is a difficult process, as both quantitative and qualitative factors have to be evaluated. Additionally, there is no formal guidance for how to implement the materiality concepts discussed in the auditing standards. Although they are sometimes difficult to make, good materiality judgments are crucial for the conduct of a successful audit as poor judgments can result in an audit that is ineffective and/or inefficient. This report...

  5. Guidance for the Review of Changes to Human Actions

    Science.gov (United States)

    2004-02-01

    NUREG -1764 Guidance for the Review of Changes to Human Actions AA Final Report m 20100715129 •"eaii U.S. Nuclear Regulatory Commission...Material As of November 1999, you may electronically access NUREG -series publications and other NRC records at NRC’s Public Electronic Reading Room at...http://www.nrc.gov/readinq-rm.html. Publicly released records include, to name a few, NUREG -series publications; Federal Register notices

  6. 血清EBV VCA-IgA、EA-IgA与鼻咽癌TNM分期的相关性

    Institute of Scientific and Technical Information of China (English)

    钟琼; 吴仁瑞; 肖震宇; 钟豪; 邓江华; 曾爱群

    2012-01-01

    目的:通过对血清EBV壳蛋白抗体VCA-IgA、EA-IgA的滴度大小和鼻咽癌分期的分析,探讨血清EBVVCA-IgA、EA-IgA抗体滴度与鼻咽癌TNM分期、临床分期的相关性.方法:研究收集鼻咽癌患者76例(鼻咽癌组),健康体检者50例(正常对照组).取血清,采用免疫酶标法检测受试者血清EBV VCA-IgA、EA-IgA滴度,用t检验分析鼻咽癌患者与正常人血清EBV VCA-IgA、EA-IgA滴度的差异.对不同分期鼻咽癌患者的血清EBVVCA-IgA、EA-IgA滴度进行F与q检验,观察各分期患者血清EBV VCA-IgA、EA-IgA滴度的差异性.结果:(1)鼻因癌患者血清EBV VCA-IgA、EA-IgA滴度与正常人比较有统计学差异(P <0.001).(2)鼻咽癌患者TNM分期与血清EBV VCA-IgA、EA-IgA几何、对数平均滴度的研究表明,对T分期各分期组间、N分期各分期组间而言,血清EBV VCA-IgA、EA-IgA滴度比较均有统计学意义(P<0.01),而且随着分期的上升滴度也随之升高.T分期与N分期中血清EBV VCA-IgA、EA-IgA滴度组间比较,除T分期与N分期的VCA-IgA比较无统计学差异外,其他均有统计学差异(P<0.01,P<0.05).(3)鼻咽癌临床分期与血清EBV VCA-IgA、EA-IgA滴度的相关性分析研究提示,鼻咽癌临床分期与血清EBV VCA-IgA、EA-IgA滴度均呈正相关,显著性检验有统计学意义(P<0.01).结论:(1)鼻咽癌患者血清EBV VCA-IgA、EA-IgA滴度与正常人比较均有统计学差异,说明EBV感染与鼻咽癌发病有密切关系.(2)鼻咽癌分期与血清EBV VCA-IgA、EA-IgA滴度均呈正相关,说明血清EBV VCA-IgA、EA-IgA与肿瘤负荷关系密切,肿瘤负荷越大,滴度越高.

  7. Exotic geophysical phenomena observed in an environmental neutron flux study using EAS PRISMA detectors

    Directory of Open Access Journals (Sweden)

    Alekseenko Victor

    2017-01-01

    Full Text Available Some exotic geophysical events are observed by a global net of electron-neutron detectors (en-detectors developed in the framework of the PRISMA EAS project. Our en-detectors running both on the Earth's surface and underground are continuously measuring the environmental thermal neutron flux. Thermal neutrons are in equilibrium with media and are therefore sensitive to many geophysical phenomena, which are exotic for people studying ultra high-energy cosmic rays or carrying out low background experiments deep underground.

  8. Evaluation of a wide-sky survey method for EAS experiments

    Science.gov (United States)

    Li, Taoli; Liu, Maoyuan; Cui, Shuwang; Hou, Zhengtao

    2012-12-01

    Several ground-based extensive air shower (EAS) experiments such as As γ and Milagro have observed that CRs show large scale anisotropy in the TeV energy region with an amplitude of about 0.1%. The amplitude of anisotropy is so weak that we have to deal carefully with potential errors introduced by analysis methods. In this paper, we discuss a method based on χ2-iteration algorithm for wide sky survey analysis in the use of equi-zenith angle method with large sample data. The results show that χ2-iteration method leads to accurate and reasonable results in the case of large scale anisotropy in data samples.

  9. 2R-regeneration in a monolithically integrated four-section SOA-EA chip

    DEFF Research Database (Denmark)

    Vivero, Tania; Calabretta, Nicola; Tafur Monroy, Idelfonso

    2009-01-01

    are measured. Results show that by cascading two-pairs of SOA–EAs a steep static transfer function is achieved. Dynamical measurements show large improvements in extinction ratio as well as a large improvement in the receiver-sensitivity when used as a regenerator for NRZ signals at 10 Gb/s.......Optical regeneration using a monolithically integrated chip formed by a cascade of semiconductor optical amplifiers and saturable absorbers is investigated. Static transfer functions, signal reshaping, extinction ratio enhancement, noise dynamics and device dependence on operation conditions...

  10. Electron attachment rate constant measurement by photoemission electron attachment ion mobility spectrometry (PE-EA-IMS)

    Science.gov (United States)

    Su, Desheng; Niu, Wenqi; Liu, Sheng; Shen, Chengyin; Huang, Chaoqun; Wang, Hongmei; Jiang, Haihe; Chu, Yannan

    2012-12-01

    Photoemission electron attachment ion mobility spectrometry (PE-EA-IMS), with a source of photoelectrons induced by vacuum ultraviolet radiation on a metal surface, has been developed to study electron attachment reaction at atmospheric pressure using nitrogen as the buffer gas. Based on the negative ion mobility spectra, the rate constants for electron attachment to tetrachloromethane and chloroform were measured at ambient temperature as a function of the average electron energy in the range from 0.29 to 0.96 eV. The experimental results are in good agreement with the data reported in the literature.

  11. Population Size vs. Mutation Strength for the (1+λ) EA on OneMax

    DEFF Research Database (Denmark)

    Gießen, Christian; Witt, Carsten

    2015-01-01

    The (1+1) EA with mutation probability c/n, where c>0 is an arbitrary constant, is studied for the classical OneMax function. Its expected optimization time is analyzed exactly (up to lower order terms) as a function of c and λ. It turns out that 1/n is the only optimal mutation probability if λ=......, irrespectively of it being less than 1 or greater. The results are obtained by a careful study of order statistics of the binomial distribution and variable drift theorems for upper and lower bounds....

  12. Optimal guidance for reentry vehicles based on indirect Legendre pseudospectral method

    Science.gov (United States)

    Tian, Bailing; Zong, Qun

    2011-04-01

    Development of a feasible guidance scheme for reentry vehicles is a challenge because of its significant nonlinearity and multi-constraints. A method for the implementation of three-degree-of-freedom guidance for constrained reentry vehicle is presented in the paper. First, the constrained trajectory is generated by Legendre pseudospectral method (LPM) and then the feasibily of the trajectory is validated. Based on the obtained reference trajectory, the guidance problem is converted into a trajectory state regulation problem which is a linear time varying system. A robust state feedback guidance law is generated in real time using indirect Legendre pseudospectral feedback method. Finally, simulation results illustrate that the overall guidance scheme can lead to a very accurately controlled flight with all the constraints satisfied even in the presence of initial state uncertainty.

  13. Optimum PN Guidance Law for Maneuvering Target

    Institute of Scientific and Technical Information of China (English)

    SUN Bao-cai; QI Zai-kang

    2007-01-01

    An optimum PN guidance law for maneuvering target is developed using optimal control theory. By estimating the target position and setting the cost function, the guidance law can be deduced even without knowing the missile lateral acceleration. Since the quadratic cost function can make a compromise between the miss distance andthe control constraint, the optimum guidance law obtained is more general. Also, introduced line of sight rate as the input, a practical form of this guidance law is derived. The simulation results show the effectiveness of the guidance laws.

  14. 77 FR 33779 - Interim Staff Guidance JLD-ISG-2012-01; Compliance With Order EA-12-049, Order Modifying Licenses...

    Science.gov (United States)

    2012-06-07

    ... conducted public meetings to discuss enhanced mitigation strategies intended to maintain or restore core... Accession No. ML11353A008). FLEX is proposed as a strategy to fulfill the key safety functions of core... With Regard to Requirements for Mitigation Strategies for Beyond-Design-Basis External Events AGENCY...

  15. Dopaminergic axon guidance: which makes what?

    Directory of Open Access Journals (Sweden)

    Laetitia ePrestoz

    2012-07-01

    Full Text Available Mesotelencephalic pathways in the adult central nervous system have been studied in great detail because of their implication in major physiological functions as well as in psychiatric, neurological and neurodegenerative diseases. However, the ontogeny of these pathways and the molecular mechanisms that guide dopaminergic axons during embryogenesis have been only recently studied. This line of research is of crucial interest for the repair of lesioned circuits in adulthood following neurodegenerative diseases or common traumatic injuries. For instance, in the adult, the anatomic and functional repair of the nigrostriatal pathway following dopaminergic embryonic neuron transplantation suggests that specific guidance cues exist which govern embryonic fibers outgrowth, and suggests that axons from transplanted embryonic cells are able to respond to theses cues, which then guide them to their final targets. In this review, we first synthesize the work that has been performed in the last few years on developing mesotelencephalic pathways, and summarize the current knowledge on the identity of cellular and molecular signals thought to be involved in establishing mesotelencephalic dopaminergic neuronal connectivity during embryogenesis in the central nervous system of rodents. Then, we review the modulation of expression of these molecular signals in the lesioned adult brain and discuss their potential role in remodeling the mesotelencephalic dopaminergic circuitry, with a particular focus on Parkinson’s disease. Identifying guidance molecules involved in the connection of grafted cells may be useful for cellular therapy in Parkinsonian patients, as these molecules may help direct axons from grafted cells along the long distance they have to travel from the substantia nigra to the striatum.

  16. 75 FR 13766 - Guidance for Industry on the Content and Format of the Dosage and Administration Section of...

    Science.gov (United States)

    2010-03-23

    ..., 2006 (71 FR 3998), FDA issued final guidances on the format and content of the ``Adverse Reactions...,'' ``Contraindications,'' and ``Boxed Warning'' sections of labeling. In the Federal Register of March 3, 2009 (74 FR... of labeling. The labeling requirements (71 FR 3922) and these guidances are intended to...

  17. 77 FR 55230 - Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-01; Compliance With...

    Science.gov (United States)

    2012-09-07

    ... COMMISSION Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-01; Compliance With...-Learned Project Directorate interim staff guidance; issuance. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC or the Commission) is issuing the Final Japan Lessons-Learned Project Directorate...

  18. 77 FR 55232 - Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-03; Compliance With...

    Science.gov (United States)

    2012-09-07

    ... COMMISSION Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-03; Compliance With...: Nuclear Regulatory Commission (NRC). ACTION: Japan Lessons-Learned Project Directorate Interim Staff... Final Japan Lessons-Learned Project Directorate (JLD) Interim Staff Guidance (ISG),...

  19. 77 FR 55231 - Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-02; Compliance With...

    Science.gov (United States)

    2012-09-07

    ... COMMISSION Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2012-02; Compliance With...: Nuclear Regulatory Commission (NRC). ACTION: Japan Lessons-Learned Project Directorate interim staff... Final Japan Lessons-Learned Project Directorate Interim Staff Guidance (JLD-ISG),...

  20. 76 FR 81510 - Draft Guidance for Industry and Food and Drug Administration Staff; the 510(k) Program...

    Science.gov (United States)

    2011-12-28

    ... titled ``The New 510(k) Paradigm--Alternate Approaches to Demonstrating Substantial Equivalence in...) Paradigm Guidance. FDA recognizes and supports efforts for global convergence of regulatory systems, and in... draft guidance, when finalized, will represent the Agency's current thinking on the 510(k) decision...

  1. 76 FR 2681 - Amended Environmental Impact Statement Filing System Guidance for Implementing 40 CFR 1506.9 and...

    Science.gov (United States)

    2011-01-14

    ... AGENCY Amended Environmental Impact Statement Filing System Guidance for Implementing 40 CFR 1506.9 and... guidelines to implement its EIS filing responsibilities. The purpose of the EPA Filing System Guidelines is to provide guidance to Federal agencies on filing EISs, including draft, final, and supplemental...

  2. 77 FR 51530 - Amended Environmental Impact Statement Filing System Guidance for Implementing 40 CFR 1506.9 and...

    Science.gov (United States)

    2012-08-24

    ... AGENCY Amended Environmental Impact Statement Filing System Guidance for Implementing 40 CFR 1506.9 and... guidelines to implement its EIS filing responsibilities. The purpose of the EPA Filing System Guidelines is to provide guidance to Federal agencies on filing EISs, including draft, final, and supplemental...

  3. Technical bases and guidance for the use of composite soil sampling for demonstrating compliance with radiological release criteria

    Energy Technology Data Exchange (ETDEWEB)

    Vitkus, Timothy J. [Oak Ridge Institute for Science and Education, Oak Ridge, TN (United States). Independent Environmental Assessment and Verification Program

    2012-04-24

    This guidance provides information on methodologies and the technical bases that licensees should consider for incorporating composite sampling strategies into final status survey (FSS) plans. In addition, this guidance also includes appropriate uses of composite sampling for generating the data for other decommissioning site investigations such as characterization or other preliminary site investigations.

  4. 78 FR 14305 - Draft Guidance for Industry and Food and Drug Administration Staff; Types of Communication During...

    Science.gov (United States)

    2013-03-05

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry and Food and Drug Administration... and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and Drug Administration (FDA) is... efficiency of the review process. This draft guidance is not final nor is it in effect at this time....

  5. 78 FR 16286 - Neal Smith National Wildlife Refuge, Jasper County, IA; Final Comprehensive Conservation Plan and...

    Science.gov (United States)

    2013-03-14

    ... Fish and Wildlife Service Neal Smith National Wildlife Refuge, Jasper County, IA; Final Comprehensive... significant impact (FONSI) for the Environmental Assessment (EA) for Neal Smith National Wildlife Refuge... . Include ``Neal Smith Final CCP'' in the subject line of the message. U.S. Mail: Neal Smith...

  6. Europeanization through students’ lens: EU versus EaP citizens. Is there a collective identity?

    Directory of Open Access Journals (Sweden)

    Elena-Alexandra GORGOS

    2016-12-01

    Full Text Available The process of Europeanization has been intensively discussed and participation in debates has been vigorously tested by the academic world, mostly concerned with examining political personalities. This process is often seen through a political and economic view, ignoring the spiritual part pointing to a collective identity rationale. Hereby, our interest consists of finding how this concept is perceived through students’ lens. We aim at investigating students’ opinions, revealing young citizens’ points of view. The conducted research is qualitative, consisting of in-depth interviews, for discovering participants’ standpoints and attitudes towards admitting European bonds and becoming Europeans not just as frame, but in a substantial way, from the perspective of belongingness to a European Union (EU member state or to an Eastern Partnership (EaP member state. As the findings show, the bond with the European Union is seen through a political and cultural approach. Students’ understanding of the Europeanization process is varied, and so are their endeavours of spreading the importance to adhere to the European Union and to share the European spirit among students belonging to EaP states.

  7. Micro Extended[X] Enterprises & An Ea Framework Best Suited For Them.

    Directory of Open Access Journals (Sweden)

    Avinash R Padole

    2016-03-01

    Full Text Available “SMiXE’s – Small & Micro Extended Enterprises”, in automobile industry, though referred as Small & Micro, but forms a bulk or a huge base of the automobile Cluster/ Pyramid (see Fig 1 below in terms of people employed, work done by them in tot up. It compliments the auto industry in absorbing the cost pressure and at the same time facilitates the auto industry in segregating the less efficient routine as well as menial work towards the bottom of the pyramid. Freeing the OEM to focus on their core activities. By their very “Nature & Need”, SMiXE have to be very “Agile, Cost Competitive and Adaptive” by their “Nature”, as all OEM’s (Global & Local are being forced to adapt new, improved, environment friendly and fuel efficient standards. The environment in which they (SMiXE exist and to the very market (“Need” that they cater is very dynamic. Keeping the above mentioned points and the constraints mentioned below, in this paper we will be evaluating the best suited EA framework which will enable us in providing a viable EA solution for SMiXE’s.

  8. Ammonium acetate enhances solvent production by Clostridium acetobutylicum EA 2018 using cassava as a fermentation medium.

    Science.gov (United States)

    Gu, Yang; Hu, Shiyuan; Chen, Jun; Shao, Lijun; He, Huiqi; Yang, Yunliu; Yang, Sheng; Jiang, Weihong

    2009-09-01

    Cassava, due to its high starch content and low cost, is a promising candidate substrate for large-scale fermentation processes aimed at producing the solvents acetone, butanol and ethanol (ABE). However, the solvent yield from the fermentation of cassava reaches only 60% of that achieved by fermenting corn. We have found that the addition of ammonium acetate (CH(3)COONH(4)) to the cassava medium significantly promotes solvent production from cassava fermented by Clostridium acetobutylicum EA 2018, a mutant with a high butanol ratio. When cassava medium was supplemented with 30 mM ammonium acetate, the acetone, butanol and total solvent production reached 5.0, 13.0 and 19.4 g/l, respectively, after 48 h of fermentation. This level of solvent production is comparable to that obtained from corn medium. Both ammonium (NH(4) (+)) and acetate (CH(3)COO(-)) were required for increased solvent synthesis. We also demonstrated substantially increased acetic and butyric acid accumulation during the acidogenesis phase as well as greater acid re-assimilation during the solventogenesis period in ammonium acetate-supplemented cassava medium. Reverse transcription-polymerase chain reaction analysis indicated that the transcription of several genes encoding enzymes related to acidogenesis and solventogenesis in C. acetobutylicum EA 2018 were enhanced by the addition of ammonium acetate to the cassava medium.

  9. Differentiation of partial acylglycerols derived from different animal fats by EA-IRMS and GCMS techniques

    Energy Technology Data Exchange (ETDEWEB)

    Nina Naquiah, A.N.; Marikkar, J.M.N.; Shuhaimi, M.

    2016-07-01

    A study was carried out to compare partial acylglycerols of lard with those of chicken fat, beef fat and mutton fat using Gas Chromatography Mass Spectrometry (GC-MS) and Elemental Analysis–Isotope Ratio Mass Spectrometry (EA-IRMS). Mono- (MAG) and di-(DAG) acylglycerols of animal fats were prepared according to a chemical glycerolysis method and isolated using column chromatography. The fatty acid composition and δ13C carbon isotope ratio of MAG and DAG derived from individual animal fat were determined separately to establish their identity characteristics. The results showed that the δ13C values of MAG and DAG of lard were significantly different from those of MAG and DAG derived from chicken fat, beef fat and mutton fat. According to the loading plots based on a principle component analysis (PCA), fatty acids namely stearic, oleic and linoleic were the most discriminating parameters to distinctly identify MAG and DAG derived from different animal fats. This demonstrated that the EA-IRMS and the PCA of fatty acid data have considerable potential for discriminating MAG and DAG derived from lard from other animal fats for Halal authentication purposes. (Author)

  10. From Star-Forming Spirals to Passive Spheroids: Integral Field Spectroscopy of E+A Galaxies

    CERN Document Server

    Swinbank, Mark; Bower, Richard; Zabludoff, Ann; Lucey, John; McGee, Sean; Miller, Chris; Nichol, Robert

    2011-01-01

    We present three dimensional spectroscopy of eleven E+A galaxies, selected for their strong H-delta absorption but weak (or non-existent) [OII]3727 and H-alpha emission. This selection suggests that a recent burst of star-formation was triggered but subsequently abruptly ended. We probe the spatial and spectral properties of both the young (~1Gyr) and old (few Gyr) stellar populations. Using the H-delta equivalent widths we estimate that the burst masses must have been at least 10% by mass (Mburst~10^10Mo), which is also consistent with the star-formation history inferred from the broad-band SEDs. On average the A-stars cover ~33% of the galaxy image, extending over 2-15kpc^2, indicating that the characteristic E+A signature is a property of the galaxy as a whole and not due to a heterogeneous mixture of populations. In approximately half of the sample, we find that the A-stars, nebular emission, and continuum emission are not co-located, suggesting that the newest stars are forming in a different place than ...

  11. Numerical simulation of a sheet metal extrusion process by using thermal-mechanical coupling EAS FEM

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The thermal-mechanical coupling finite element method (FEM) was used to simulate a non-isothermal sheet metal extrusion process. On the basis of the finite plasticity consistent with multiplicative decomposition of the deformation gradient, the enhanced assumed strain (EAS) FEM was applied to carry out the numerical simulation. In order to make the computation reliable and avoid hourglass mode in the EAS element under large compressive strains, an alterative form of the original enhanced deformation gradient was employed. In addition, reduced factors were used in the computation of the element local internal parameters and the enhanced part of elemental stiffness. Numerical resultsshow that the hourglass can be avoided in compression region. In the thermal phase, the boundary energy dissipation due to heat convection was taken into account. As an example, a circular steel plate protruded by cylindrical punch was simulated. The step-wise decoupled strategyis adopted to handle coupling between mechanical deformation and the temperature variation. By comparing with the experimental results, thenumerical simulation was verified.

  12. Gamma-ray bounds from EAS detectors and heavy decaying dark matter constraints

    Energy Technology Data Exchange (ETDEWEB)

    Esmaili, Arman [INFN, Laboratori Nazionali del Gran Sasso,Assergi, AQ (Italy); Serpico, Pasquale Dario [LAPTh, Univ. de Savoie Mont Blanc, CNRS,B.P. 110, Annecy-le-Vieux, F-74941 (France)

    2015-10-07

    The very high energy Galactic γ-ray sky is partially opaque in the (0.1–10) PeV energy range. In the light of the recently detected high energy neutrino flux by IceCube, a comparable very high energy γ-ray flux is expected in any scenario with a sizable Galactic contribution to the neutrino flux. Here we elaborate on the peculiar energy and anisotropy features imposed upon these very high energy γ-rays by the absorption on the cosmic microwave background photons and Galactic interstellar light. As a notable application of our considerations, we study the prospects of probing the PeV-scale decaying DM scenario, proposed as a possible source of IceCube neutrinos, by extensive air shower (EAS) cosmic ray experiments. In particular, we show that anisotropy measurements at EAS experiments are already sensitive to τ{sub DM}∼O(10{sup 27}) s and future measurements, using better gamma/hadron separation, can improve the limit significantly.

  13. A randomized trial of 4-aminopyridine in EA2 and related familial episodic ataxias.

    Science.gov (United States)

    Strupp, M; Kalla, R; Claassen, J; Adrion, C; Mansmann, U; Klopstock, T; Freilinger, T; Neugebauer, H; Spiegel, R; Dichgans, M; Lehmann-Horn, F; Jurkat-Rott, K; Brandt, T; Jen, J C; Jahn, K

    2011-07-19

    The therapeutic effects of 4-aminopyridine (4AP) were investigated in a randomized, double-blind, crossover trial in 10 subjects with familial episodic ataxia with nystagmus. After randomization, placebo or 4AP (5 mg 3 times daily) was administered for 2 3-month-long treatment periods separated by a 1-month-long washout period. The primary outcome measure was the number of ataxia attacks per month; the secondary outcome measures were the attack duration and patient-reported quality of life (Vestibular Disorders Activities of Daily Living Scale [VDADL]). Nonparametric tests and a random-effects model were used for statistical analysis. The diagnosis of episodic ataxia type 2 (EA2) was genetically confirmed in 7 subjects. Patients receiving placebo had a median monthly attack frequency of 6.50, whereas patients taking 4AP had a frequency of 1.65 (p = 0.03). Median monthly attack duration decreased from 13.65 hours with placebo to 4.45 hours with 4AP (p = 0.08). The VDADL score decreased from 6.00 to 1.50 (p = 0.02). 4AP was well-tolerated. This controlled trial on EA2 and familial episodic ataxia with nystagmus demonstrated that 4AP decreases attack frequency and improves quality of life. This crossover study provides Class II evidence that 4AP decreases attack frequency and improves the patient-reported quality of life in patients with episodic ataxia and related familial ataxias.

  14. Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018

    Directory of Open Access Journals (Sweden)

    Wang Shengyue

    2011-02-01

    Full Text Available Abstract Background Clostridium acetobutylicum, a gram-positive and spore-forming anaerobe, is a major strain for the fermentative production of acetone, butanol and ethanol. But a previously isolated hyper-butanol producing strain C. acetobutylicum EA 2018 does not produce spores and has greater capability of solvent production, especially for butanol, than the type strain C. acetobutylicum ATCC 824. Results Complete genome of C. acetobutylicum EA 2018 was sequenced using Roche 454 pyrosequencing. Genomic comparison with ATCC 824 identified many variations which may contribute to the hyper-butanol producing characteristics in the EA 2018 strain, including a total of 46 deletion sites and 26 insertion sites. In addition, transcriptomic profiling of gene expression in EA 2018 relative to that of ATCC824 revealed expression-level changes of several key genes related to solvent formation. For example, spo0A and adhEII have higher expression level, and most of the acid formation related genes have lower expression level in EA 2018. Interestingly, the results also showed that the variation in CEA_G2622 (CAC2613 in ATCC 824, a putative transcriptional regulator involved in xylose utilization, might accelerate utilization of substrate xylose. Conclusions Comparative analysis of C. acetobutylicum hyper-butanol producing strain EA 2018 and type strain ATCC 824 at both genomic and transcriptomic levels, for the first time, provides molecular-level understanding of non-sporulation, higher solvent production and enhanced xylose utilization in the mutant EA 2018. The information could be valuable for further genetic modification of C. acetobutylicum for more effective butanol production.

  15. Comparative genomic and transcriptomic analysis revealed genetic characteristics related to solvent formation and xylose utilization in Clostridium acetobutylicum EA 2018

    Science.gov (United States)

    2011-01-01

    Background Clostridium acetobutylicum, a gram-positive and spore-forming anaerobe, is a major strain for the fermentative production of acetone, butanol and ethanol. But a previously isolated hyper-butanol producing strain C. acetobutylicum EA 2018 does not produce spores and has greater capability of solvent production, especially for butanol, than the type strain C. acetobutylicum ATCC 824. Results Complete genome of C. acetobutylicum EA 2018 was sequenced using Roche 454 pyrosequencing. Genomic comparison with ATCC 824 identified many variations which may contribute to the hyper-butanol producing characteristics in the EA 2018 strain, including a total of 46 deletion sites and 26 insertion sites. In addition, transcriptomic profiling of gene expression in EA 2018 relative to that of ATCC824 revealed expression-level changes of several key genes related to solvent formation. For example, spo0A and adhEII have higher expression level, and most of the acid formation related genes have lower expression level in EA 2018. Interestingly, the results also showed that the variation in CEA_G2622 (CAC2613 in ATCC 824), a putative transcriptional regulator involved in xylose utilization, might accelerate utilization of substrate xylose. Conclusions Comparative analysis of C. acetobutylicum hyper-butanol producing strain EA 2018 and type strain ATCC 824 at both genomic and transcriptomic levels, for the first time, provides molecular-level understanding of non-sporulation, higher solvent production and enhanced xylose utilization in the mutant EA 2018. The information could be valuable for further genetic modification of C. acetobutylicum for more effective butanol production. PMID:21284892

  16. Guidance document for structured reporting of diuresis renography.

    Science.gov (United States)

    Taylor, Andrew T; Blaufox, M Donald; De Palma, Diego; Dubovsky, Eva V; Erbaş, Belkis; Eskild-Jensen, Anni; Frøkiær, Jørgen; Issa, Muta M; Piepsz, Amy; Prigent, Alain

    2012-01-01

    This Guidance Document for structured reporting of diuresis renography in adults was developed by the International Scientific Committee of Radionuclides in Nephro-urology (ISCORN; http://www.iscorn.org). ISCORN chose diuresis renography for its first structured report Guidance Document because suspected obstruction is the most common reason for referral, most radionuclide renal studies are conducted at institutions that perform fewer than 3 studies per week, and a large percentage of studies are interpreted by physicians with limited training in nuclear medicine. Ten panelists were asked to categorize specific reporting elements as essential, recommended, optional (without sufficient data to support a higher ranking), and unnecessary (does not contribute to scan interpretation or quality assurance). The final document was developed through an iterative series of comments and questionnaires with a majority vote required to place an element in a specific category. The Guidance Document recommends a reporting structure organized into indications, clinical history, study procedure, findings and impression and specifies the elements considered essential or recommended in each category. The Guidance Document is not intended to be restrictive but, rather, to provide a basic structure and rationale so that the diuresis renography report will: (1) communicate the results to the referring physician in a clear and concise manner designed to optimize patient care; (2) contain the essential elements required to evaluate and interpret the study; (3) clearly document the technical components of the study necessary for accountability, quality assurance and reimbursement; and (4) encourage clinical research by facilitating better comparison and extrapolation of results between institutions.

  17. Hands-Free System for Bronchoscopy Planning and Guidance.

    Science.gov (United States)

    Khare, Rahul; Bascom, Rebecca; Higgins, William E

    2015-12-01

    Bronchoscopy is a commonly used minimally invasive procedure for lung-cancer staging. In standard practice, however, physicians differ greatly in their levels of performance. To address this concern, image-guided intervention (IGI) systems have been devised to improve procedure success. Current IGI bronchoscopy systems based on virtual bronchoscopic navigation (VBN), however, require involvement from the attending technician. This lessens physician control and hinders the overall acceptance of such systems. We propose a hands-free VBN system for planning and guiding bronchoscopy. The system introduces two major contributions. First, it incorporates a new procedure-planning method that automatically computes airway navigation plans conforming to the physician's bronchoscopy training and manual dexterity. Second, it incorporates a guidance strategy for bronchoscope navigation that enables user-friendly system control via a foot switch, coupled with a novel position-verification mechanism. Phantom studies verified that the system enables smooth operation under physician control, while also enabling faster navigation than an existing technician-assisted VBN system. In a clinical human study, we noted a 97% bronchoscopy navigation success rate, in line with existing VBN systems, and a mean guidance time per diagnostic site = 52 s. This represents a guidance time often nearly 3 min faster per diagnostic site than guidance times reported for other technician-assisted VBN systems. Finally, an ergonomic study further asserts the system's acceptability to the physician and long-term potential.

  18. Analysing Interplanetary Probe Guidance Accuracy

    Directory of Open Access Journals (Sweden)

    S. V. Sukhova

    2016-01-01

    Full Text Available The paper presents a guidance accuracy analysis and estimates delta-v budget required to provide the trajectory correction maneuvers for direct interplanetary flights (without midcourse gravity assists. The analysis takes into consideration the orbital hyperbolic injection errors (depend on a selected launch vehicle and ascent trajectory and the uncertainties of midcourse correction maneuvers.The calculation algorithm is based on Monte Carlo simulation and Danby’s matrix methods (the matrizant of keplerian motion. Danby’s method establishes a link between the errors of the spacecraft state vectors at different flight times using the reference keplerian orbit matrizant. Utilizing the nominal trajectory parameters and the covariance matrix of launch vehicle injection errors the random perturbed orbits are generated and required velocity corrections are calculated. The next step is to simulate midcourse maneuver performance uncertainty using the midcourse maneuver covariance matrix. The obtained trajectory correction impulses and spacecraft position errors are statistically processed to compute required delta-v budget and dispersions ellipse parameters for different prediction intervals.As an example, a guidance accuracy analysis has been conducted for a 2022 mission to Mars and a Venus mission in 2026. The paper considers one and two midcourse correction options, as well as utilization of two different launch vehicles.The presented algorithm based on Monte Carlo simulation and Danby’s methods provides preliminary evaluation for midcourse corrections delta-v budget and spacecraft position error. The only data required for this guidance accuracy analysis are a reference keplerian trajectory and a covariance matrix of the injection errors. Danby’s matrix method allows us to take into account also the other factors affecting the trajectory thereby increasing the accuracy of analysis.

  19. Denmark: Welfare Society, Social Justice and the Role of Career Guidance

    DEFF Research Database (Denmark)

    Thomsen, Rie

    Denmark: Welfare Society, Social Justice and the Role of Career Guidance Dr. Rie Thomsen, Aarhus University in Copenhagen, Denmark Denmark is a welfare state in Scandinavia and amongst the most equal countries in the world but it has dropped from being the most equal country in the world to number...... 11 in 10 years. This presentation considers what social justice means for educational and vocational guidance in Denmark. It covers the development in the Danish career guidance system for young people and show how the service has become more targeted towards marginalised youth. Finally different...

  20. Precision optical navigation guidance system

    Science.gov (United States)

    Starodubov, D.; McCormick, K.; Nolan, P.; Johnson, D.; Dellosa, M.; Volfson, L.; Fallahpour, A.; Willner, A.

    2016-05-01

    We present the new precision optical navigation guidance system approach that provides continuous, high quality range and bearing data to fixed wing aircraft during landing approach to an aircraft carrier. The system uses infrared optical communications to measure range between ship and aircraft with accuracy and precision better than 1 meter at ranges more than 7.5 km. The innovative receiver design measures bearing from aircraft to ship with accuracy and precision better than 0.5 mRad. The system provides real-time range and bearing updates to multiple aircraft at rates up to several kHz, and duplex data transmission between ship and aircraft.

  1. Orthobiologic Interventions Using Ultrasound Guidance.

    Science.gov (United States)

    Malanga, Gerard; Abdelshahed, Dena; Jayaram, Prathap

    2016-08-01

    The application of regenerative therapies for the treatment of musculoskeletal conditions has emerged over the last decade with recent acceleration. These include prolotherapy, platelet-rich plasma, and mesenchymal stem cell therapy. These strategies augment the body's innate physiology to heal pathologic processes. This article presents an overview of platelet-rich plasma and mesenchymal stem cell therapy for the treatment of musculoskeletal injuries. A brief literature review is included, as are techniques for the use of ultrasound guidance to assist with these procedures. Copyright © 2016 Elsevier Inc. All rights reserved.

  2. Research Progress on E+A (Post-Starburst) Galaxies%E+A星系的研究进展

    Institute of Scientific and Technical Information of China (English)

    李金荣; 林宣滨; 潘治政; 孔旭

    2011-01-01

    E+A星系的光谱具有很强的巴耳末吸收线,缺乏与恒星形成相关的发射线,将典型的椭圆星系(E)和A型恒星的光谱进行线性组合就能够拟合出这类星系的光谱.它们的颜色、形态、星族年龄等参数介于典型的早型和晚型星系之间.E+A星系近期经历了星暴活动,在星系演化进程中,它们处于晚型到早型的过渡阶段,可能在演变过程中扮演着重要角色.介绍了E+A星系的基本观测特征,并讨论了它们的形成机制、演化去向、所处的环境以及它们与AGN的关系.%The most typical characteristics of E+A galaxies are that their spectra show strong Balmer absorption lines but no significant emission lines associated with ongoing star formation. The spectra can be roughly fitted by a combination of an old elliptical galaxy (E) and a young A-type star spectrum, so named E+A galaxies. The existence of strong Balmer absorption lines indicates that E+A galaxies have undergone starburst activities, and the shortage of emission lines implies that they have quenched their star formation recently.Therefore, E+A galaxies are also interpreted as post-starburst galaxies.On the evolutionary path of some galaxies from gas-rich, stax-forming, disk-dominated blue ones into gas-poor, quiescent, bulge-dominated red ones, E+A galaxies, which are in the intermediate phase, play an important role in our understanding of galaxy formation and evolution. E+A galaxies originate mainly from merging/interaction in low density regions , especially wet merging between gas-rich galaxies, but a few cluster-related physical mechanisms also play some role, such as ram pressure stripping star-forming gas by hightemperature and high-density intracluster media. Many physical parameters of E+A galaxies are between typical early-type and late type galaxies, or close to early-type, which suggest they will eventually evolve into elliptical galaxies. Although poor groups and field environment are

  3. Search for Anti-EA(D Antibodies in Subjects with an “Isolated VCA IgG” Pattern

    Directory of Open Access Journals (Sweden)

    Massimo De Paschale

    2010-01-01

    Full Text Available The presence of an “isolated viral capsid antigen (VCA IgG” pattern in serum is not easy to interpret without the aid of further tests, such as specific immunoblotting or a virus genome search, that often give rise to organisational and economic problems. However, one alternative is to use an enzyme-linked immunosorbent assay (ELISA to detect anti-early antigen (EA antibodies, which can be found in about 85% of subjects with acute Epstein-Barr virus (EBV infections. The purpose of this work was to search for anti-EA(D antibodies in 130 samples with an isolated VCA IgG pattern at ELISA screening and classified as being indicative of past (102 cases or acute (28 cases infection on the basis of the immunoblotting results. Thirty-seven samples (28.5% were positive for anti-EA(D, of which 25 (89.3% had been classified by immunoblotting as indicating acute and 12 (11.8% past EBV infection. This difference was statistically significant (<.01. The results of our search for anti-EA(D antibodies correctly identified nearly 90% of acute (presence or past EBV infections (absence. When other tests are not available, the search for anti-EA antibodies may therefore be helpful in diagnosing patients with an isolated VCA IgG pattern at screening tests.

  4. Massively parallel DNA sequencing successfully identifies new causative mutations in deafness genes in patients with cochlear implantation and EAS.

    Directory of Open Access Journals (Sweden)

    Maiko Miyagawa

    Full Text Available Genetic factors, the most common etiology in severe to profound hearing loss, are one of the key determinants of Cochlear Implantation (CI and Electric Acoustic Stimulation (EAS outcomes. Satisfactory auditory performance after receiving a CI/EAS in patients with certain deafness gene mutations indicates that genetic testing would be helpful in predicting CI/EAS outcomes and deciding treatment choices. However, because of the extreme genetic heterogeneity of deafness, clinical application of genetic information still entails difficulties. Target exon sequencing using massively parallel DNA sequencing is a new powerful strategy to discover rare causative genes in Mendelian disorders such as deafness. We used massive sequencing of the exons of 58 target candidate genes to analyze 8 (4 early-onset, 4 late-onset Japanese CI/EAS patients, who did not have mutations in commonly found genes including GJB2, SLC26A4, or mitochondrial 1555A>G or 3243A>G mutations. We successfully identified four rare causative mutations in the MYO15A, TECTA, TMPRSS3, and ACTG1 genes in four patients who showed relatively good auditory performance with CI including EAS, suggesting that genetic testing may be able to predict the performance after implantation.

  5. Flight Guidance System Requirements Specification

    Science.gov (United States)

    Miller, Steven P.; Tribble, Alan C.; Carlson, Timothy M.; Danielson, Eric J.

    2003-01-01

    This report describes a requirements specification written in the RSML-e language for the mode logic of a Flight Guidance System of a typical regional jet aircraft. This model was created as one of the first steps in a five-year project sponsored by the NASA Langley Research Center, Rockwell Collins Inc., and the Critical Systems Research Group of the University of Minnesota to develop new methods and tools to improve the safety of avionics designs. This model will be used to demonstrate the application of a variety of methods and techniques, including safety analysis of system and subsystem requirements, verification of key properties using theorem provers and model checkers, identification of potential sources mode confusion in system designs, partitioning of applications based on the criticality of system hazards, and autogeneration of avionics quality code. While this model is representative of the mode logic of a typical regional jet aircraft, it does not describe an actual or planned product. Several aspects of a full Flight Guidance System, such as recovery from failed sensors, have been omitted, and no claims are made regarding the accuracy or completeness of this specification.

  6. Guidance on tiered risk assessment for plant protection products for aquatic organisms in edge‐of‐field surface waters

    National Research Council Canada - National Science Library

    EFSA Panel on Plant Protection Products and their Residues (PPR)

    2013-01-01

    ...) on Aquatic Ecotoxicology under Council Directive 91/414/EEC (SANCO/3268/2001 rev.4 (final), 17 October 2002). This Guidance of the PPR Panel is the first of three requested deliverables within this mandate...

  7. Oxygen isotope analysis of phosphate: improved precision using TC/EA CF-IRMS.

    Science.gov (United States)

    LaPorte, D F; Holmden, C; Patterson, W P; Prokopiuk, T; Eglington, B M

    2009-06-01

    Oxygen isotope values of biogenic apatite have long demonstrated considerable promise for paleothermometry potential because of the abundance of material in the fossil record and greater resistance of apatite to diagenesis compared to carbonate. Unfortunately, this promise has not been fully realized because of relatively poor precision of isotopic measurements, and exceedingly small size of some substrates for analysis. Building on previous work, we demonstrate that it is possible to improve precision of delta18O(PO4) measurements using a 'reverse-plumbed' thermal conversion elemental analyzer (TC/EA) coupled to a continuous flow isotope ratio mass spectrometer (CF-IRMS) via a helium stream [Correction made here after initial online publication]. This modification to the flow of helium through the TC/EA, and careful location of the packing of glassy carbon fragments relative to the hot spot in the reactor, leads to narrower, more symmetrically distributed CO elution peaks with diminished tailing. In addition, we describe our apatite purification chemistry that uses nitric acid and cation exchange resin. Purification chemistry is optimized for processing small samples, minimizing isotopic fractionation of PO4(-3) and permitting Ca, Sr and Nd to be eluted and purified further for the measurement of delta44Ca and 87Sr/86Sr in modern biogenic apatite and 143Nd/144Nd in fossil apatite. Our methodology yields an external precision of +/- 0.15 per thousand (1sigma) for delta18O(PO4). The uncertainty is related to the preparation of the Ag3PO4 salt, conversion to CO gas in a reversed-plumbed TC/EA, analysis of oxygen isotopes using a CF-IRMS, and uncertainty in constructing calibration lines that convert raw delta18O data to the VSMOW scale. Matrix matching of samples and standards for the purpose of calibration to the VSMOW scale was determined to be unnecessary. Our method requires only slightly modified equipment that is widely available. This fact, and the

  8. International governmental agencies and career guidance

    OpenAIRE

    Conger, Stuart

    1999-01-01

    The international Organization for Economic Cooperation and Development (OECD), like many national and international organizations concerned with economic development believes that career guidance has an important role in promoting the development of a country's human resources. (Mapping the future: Young People and career guidance OECD, 1996). Generally the economic development agencies always recommend that career guidance services should be strengthened. Too frequently, however, they do no...

  9. Stochastically optimized monocular vision-based navigation and guidance

    Science.gov (United States)

    Watanabe, Yoko

    -effort guidance (MEG) law for multiple target tracking is applied for a guidance design to achieve the mission. Through simulations, it is shown that the control effort can be reduced by using the MEG-based guidance design instead of a conventional proportional navigation-based one. The navigation and guidance designs are implemented and evaluated in a 6 DoF UAV flight simulation. Furthermore, the vision-based obstacle avoidance system is also tested in a flight test using a balloon as an obstacle. For monocular vision-based control problems, it is well-known that the separation principle between estimation and control does not hold. In other words, that vision-based estimation performance highly depends on the relative motion of the vehicle with respect to the target. Therefore, this thesis aims to derive an optimal guidance law to achieve a given mission under the condition of using the EKF-based relative navigation. Unlike many other works on observer trajectory optimization, this thesis suggests a stochastically optimized guidance design that minimizes the expected value of a cost function of the guidance error and the control effort subject to the EKF prediction and update procedures. A suboptimal guidance law is derived based on an idea of the one-step-ahead (OSA) optimization, in which the optimization is performed under the assumption that there will be only one more final measurement at the one time step ahead. The OSA suboptimal guidance law is applied to problems of vision-based rendezvous and vision-based obstacle avoidance. Simulation results are presented to show that the suggested guidance law significantly improves the guidance performance. The OSA suboptimal optimization approach is generalized as the n-step-ahead (nSA) optimization for an arbitrary number of n. Furthermore, the nSA suboptimal guidance law is extended to the p %-ahead suboptimal guidance by changing the value of n at each time step depending on the current time. The nSA (including the OSA) and

  10. Hybrid Guidance System for Relative Navigation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Future NASA architectures and missions will involve many distributed platforms that must work together. This in turn requires guidance, navigation and control...

  11. Using AHP Method for Educational and Vocational Guidance

    Directory of Open Access Journals (Sweden)

    Essaid EL HAJI

    2017-01-01

    Full Text Available This work focuses on the use of multi-criteria decision-making method AHP for using in educational and vocational guidance. Analytical Hierarchy Process (AHP, proposed by the mathematician Thomas Saaty in 1980, is a method of analysis greatly used in the context of a multi-criteria analysis; it allows the comparison and the choice between the preset options. To achieve this goal, a vital work, preceded the use of the AHP method, which consists in doing a prototyping of trades according to the guidance criteria and sub-criteria. The IT system based on this method allows the student to find, firstly, the activities' sectors which are the most appropriate to his/her profile, to choose subsequently the trades and finally, to identify, the potential training paths

  12. Gamma-ray bounds from EAS detectors and heavy decaying dark matter constraints

    CERN Document Server

    Esmaili, Arman

    2015-01-01

    The very high energy Galactic gamma-ray sky is partially opaque in the (0.1-10) PeV energy range. In the light of the recently detected high energy neutrino flux by IceCube, a comparable very high energy gamma-ray flux is expected in any scenario with a sizable Galactic contribution to the neutrino flux. Here we elaborate on the peculiar energy and anisotropy features imposed upon these very high energy gamma-rays by the absorption on the cosmic microwave background photons and Galactic interstellar light. As a notable application of our considerations, we study the prospects of probing the PeV-scale decaying DM scenario, proposed as a possible source of IceCube neutrinos, by extensive air shower (EAS) cosmic ray experiments.

  13. A Study of E+A Galaxies Through SDSS-MaNGA Integral Field Spectroscopy

    Science.gov (United States)

    Wally, Muhammad; Weaver, Olivia A.; Anderson, Miguel Ricardo; Liu, Allen; Falcone, Julia; Wallack, Nicole Lisa; James, Olivia; Liu, Charles

    2017-01-01

    We outline the selection process and analysis of sixteen E+A galaxies observed by the Mapping Nearby Galaxies at the Apache Point Observatory (MaNGA) survey as a part of the fourth generation of the Sloan Digital Sky Survey (SDSS-IV). We present their Integral field spectroscopy and analyze their spatial distribution of stellar ages, metallicities and other stellar population properties. We can potentially study the variation in these properties as a function of redshift. This work was supported by the Alfred P. Sloan Foundation via the SDSS-IV Faculty and Student Team (FAST) initiative, ARC Agreement #SSP483 to the CUNY College of Staten Island. This work was also supported by grants to The American Museum of Natural History, and the CUNY College of Staten Island through The National Science Foundation.

  14. The array of scintillation detectors with natural boron for EAS neutrons investigations

    Science.gov (United States)

    Gromushkin, D. M.; Bogdanov, F. A.; Khokhlov, S. S.; Kokoulin, R. P.; Kompaniets, K. G.; Petrukhin, A. A.; Shulzhenko, I. A.; Stenkin, Yu. V.; Yashin, I. I.; Yurin, K. O.

    2017-07-01

    The new URAN array has been constructed in the National Research Nuclear University MEPhI (Moscow, Russia). It is aimed at studying of primary cosmic rays in the "knee" region of energy spectrum and detects neutrons produced in interactions of EAS particles with nuclei of atmosphere or matter. The array consists of 72 detectors based on the scintillator with natural boron. Scintillator represents a silicon plate with the granules of ZnS(Ag) and B2O3 mixture. The area of the detector is 0.36 sq. m. Detectors are located on two roofs of the MEPhI laboratory buildings and are combined into clusters of 12 detectors. The structure and the main elements of the URAN array are described.

  15. Multigap resistive plate chambers for EAS study in the EEE Project

    CERN Document Server

    An, S; Badalà, A; Zichichi, A

    2007-01-01

    The EEE (Extreme Energy Events) Project, conceived by its leader Antonino Zichichi, is an experiment to study very high-energetic air showers (EAS) through the detection of the shower's muon component using a network of tracking detectors, installed in Italian high schools. The single tracking telescope is composed of three large area () Multi-gap Resistive Plate Chambers (MRPCs). The data collected by the telescopes will be used for studies of air showers and also for the search of time correlations between sites which are far apart. The first telescope, recently installed in the Liceo B. Touschek in Grottaferrata (Rome), is successfully running, and other telescopes are going to be installed in a short time in other towns, opening up the way for the first search of long-distance coincidences over a total area of .

  16. A Comparison of Radio-loud and Radio-quiet E+A Galaxies

    Science.gov (United States)

    Camacho, Yssavo; Wallack, Nicole; Learis, Anna; Liu, Charles

    2015-01-01

    E+A galaxies are systems undergoing an important evolutionary transition. Their optical spectra show significant numbers of A-type stars in an elliptical galaxy that has little to no star formation (SF). These galaxies have likely experienced a recent starburst (types. We find that the radio-loud and radio-quiet samples exhibit statistically insignificant differences in the optical, near-infrared, and mid-infrared bands. We also compare the two samples on a (J-H) vs. (H-K) color-color diagram. This work was supported by the National Science Foundation via grant AST-1004583 to the CUNY College of Staten Island, and grant AST-1004591 to the American Museum of Natural History.

  17. Application of MPVR and TL-VR with 64-row MDCT in neonates with congenital EA and distal TEF

    Institute of Scientific and Technical Information of China (English)

    Yang Wen; Yun Peng; Ren-You Zhai; Ying-Zi Li

    2011-01-01

    AIM: To assess the application of multiple planar volume reconstruction (MPVR) and three-dimensional (3D) transparency lung volume rendering (TL-VR) with 64-row multidetector-row computed tomography (MDCT) in neonates with congenital esophageal atresia (EA) and distal tracheoesophageal fistula (TEF). METHODS: Twenty neonates (17 boys, 3 girls) with EA and distal TEF at a mean age of 4.6 d (range 1-16 d) were enrolled in this study. A helical scan of 64-row MDCT was performed at the 64 mm × 0.625 mm collimation. EA and TEF were reconstructed with MPVR and TL-VR, respectively. Initial diagnosis of EA was made by chest radiography showing the inserted catheter in the proximal blind-ended esophageal pouch. Manifestations of MDCT images were compared with the findings at surgery. RESULTS: MDCT showed the proximal and distal esophageal pouches in 20 cases. No significant difference was observed in gaps between the proximal and distal esophageal pouches detected by MPVR and TLVR. The lengths of gaps between the proximal and distal esophageal pouches detected by MPVR and TL-VR correlated well with the findings at surgery (R = 0.87, P < 0.001). The images of MPVR revealed the orifice of TEF in 13 cases, while TL-VR images showed the orifice of TEF in 4 cases. CONCLUSION: EA and distal TEF can be reconstructed using MPVR and TL-VR of 64-row MDCT, which is a noninvasive technique to demonstrate the distal esophageal pouches and inter-pouch distance in neonates with EA and distal TEF.

  18. Sailuotong Prevents Hydrogen Peroxide (H2O2)-Induced Injury in EA.hy926 Cells

    Science.gov (United States)

    Seto, Sai Wang; Chang, Dennis; Ko, Wai Man; Zhou, Xian; Kiat, Hosen; Bensoussan, Alan; Lee, Simon M. Y.; Hoi, Maggie P. M.; Steiner, Genevieve Z.; Liu, Jianxun

    2017-01-01

    Sailuotong (SLT) is a standardised three-herb formulation consisting of Panax ginseng, Ginkgo biloba, and Crocus sativus designed for the management of vascular dementia. While the latest clinical trials have demonstrated beneficial effects of SLT in vascular dementia, the underlying cellular mechanisms have not been fully explored. The aim of this study was to assess the ability and mechanisms of SLT to act against hydrogen peroxide (H2O2)-induced oxidative damage in cultured human vascular endothelial cells (EAhy926). SLT (1–50 µg/mL) significantly suppressed the H2O2-induced cell death and abolished the H2O2-induced reactive oxygen species (ROS) generation in a concentration-dependent manner. Similarly, H2O2 (0.5 mM; 24 h) caused a ~2-fold increase in lactate dehydrogenase (LDH) release from the EA.hy926 cells which were significantly suppressed by SLT (1–50 µg/mL) in a concentration-dependent manner. Incubation of SLT (50 µg/mL) increased superoxide dismutase (SOD) activity and suppressed the H2O2-enhanced Bax/Bcl-2 ratio and cleaved caspase-3 expression. In conclusion, our results suggest that SLT protects EA.hy916 cells against H2O2-mediated injury via direct reduction of intracellular ROS generation and an increase in SOD activity. These protective effects are closely associated with the inhibition of the apoptotic death cascade via the suppression of caspase-3 activation and reduction of Bax/Bcl-2 ratio, thereby indicating a potential mechanism of action for the clinical effects observed. PMID:28067784

  19. Sailuotong Prevents Hydrogen Peroxide (H2O2-Induced Injury in EA.hy926 Cells

    Directory of Open Access Journals (Sweden)

    Sai Wang Seto

    2017-01-01

    Full Text Available Sailuotong (SLT is a standardised three-herb formulation consisting of Panax ginseng, Ginkgo biloba, and Crocus sativus designed for the management of vascular dementia. While the latest clinical trials have demonstrated beneficial effects of SLT in vascular dementia, the underlying cellular mechanisms have not been fully explored. The aim of this study was to assess the ability and mechanisms of SLT to act against hydrogen peroxide (H2O2-induced oxidative damage in cultured human vascular endothelial cells (EAhy926. SLT (1–50 µg/mL significantly suppressed the H2O2-induced cell death and abolished the H2O2-induced reactive oxygen species (ROS generation in a concentration-dependent manner. Similarly, H2O2 (0.5 mM; 24 h caused a ~2-fold increase in lactate dehydrogenase (LDH release from the EA.hy926 cells which were significantly suppressed by SLT (1–50 µg/mL in a concentration-dependent manner. Incubation of SLT (50 µg/mL increased superoxide dismutase (SOD activity and suppressed the H2O2-enhanced Bax/Bcl-2 ratio and cleaved caspase-3 expression. In conclusion, our results suggest that SLT protects EA.hy916 cells against H2O2-mediated injury via direct reduction of intracellular ROS generation and an increase in SOD activity. These protective effects are closely associated with the inhibition of the apoptotic death cascade via the suppression of caspase-3 activation and reduction of Bax/Bcl-2 ratio, thereby indicating a potential mechanism of action for the clinical effects observed.

  20. Computed tomography guidance for spinal intervention: basics of technique, pearls, and avoiding pitfalls.

    Science.gov (United States)

    Timpone, Vincent M; Hirsch, Joshua A; Gilligan, Christopher J; Chandra, Ronil V

    2013-01-01

    The utilization of spinal interventional pain techniques has grown rapidly over the last decade. However, practitioners use widely different techniques in these procedures, particularly in the use of image guidance. The importance of image guidance was highlighted by the fact that in recent systematic reviews on therapeutic effectiveness of epidural steroid injections and facet joint interventions, only studies that used image guidance were included. The choice of image guidance remains a matter of physician preference with conventional fluoroscopic or Computed Tomography (CT) guidance most common. There are many advantages to CT guidance for certain spinal interventional pain procedures, mainly due to increased needle tip positioning accuracy. CT guidance provides greater anatomical detail that facilitates accurate needle trajectory planning, monitoring and final placement. Unlike conventional fluoroscopy that may be hindered by tissue overlap and lack of surrounding anatomical detail CT guidance offers direct visualization of the entire needle trajectory and the surrounding soft tissue and bone structures. Large osteophytes and adjacent vascular structures can be identified and safely avoided. The goals of this narrative review are to provide a basic overview of CT techniques available for spinal interventional pain procedures, to discuss the potential advantages and disadvantages of CT guidance, to provide a simple step-by-step approach to use of CT guidance, to share technical pearls, and to discuss methods to avoid potential pitfalls. This review will provide interventional pain physicians with knowledge of relevant CT image acquisition techniques and appropriate radiation dose reduction strategies. This will contribute to increased technical success rates while reducing radiation dose to the patient and staff.

  1. Minisatellite Attitude Guidance Using Reaction Wheels

    Directory of Open Access Journals (Sweden)

    Ion STROE

    2015-06-01

    Full Text Available In a previous paper [2], the active torques needed for the minisatellite attitude guidance from one fixed attitude posture to another fixed attitude posture were determined using an inverse dynamics method. But when considering reaction/momentum wheels, instead of this active torques computation, the purpose is to compute the angular velocities of the three reaction wheels which ensure the minisatellite to rotate from the initial to the final attitude. This paper presents this computation of reaction wheels angular velocities using a similar inverse dynamics method based on inverting Euler’s equations of motion for a rigid body with one fixed point, written in the framework of the x-y-z sequence of rotations parameterization. For the particular case A=B not equal C of an axisymmetric minisatellite, the two computations are compared: the active torques computation versus the computation of reaction wheels angular velocities ̇x , ̇y and ̇z. An interesting observation comes out from this numerical study: if the three reaction wheels are identical (with Iw the moment of inertia of one reaction wheel with respect to its central axis, then the evolutions in time of the products between Iw and the derivatives of the reaction wheels angular velocities, i.e. ̇ , ̇ and ̇ remain the same and do not depend on the moment of inertia Iw.

  2. RE170、RE170/R227ea与矿物油的互溶性评价%Miscibility evaluation of RE170 and RE170/R227ea with a mineral oil

    Institute of Scientific and Technical Information of China (English)

    田田; 杨昭; 吴曦; 余壮壮

    2015-01-01

    Refrigerant R22 is scheduled to be phased out and new and environmentally friendly refrigerants RE170 and RE170/R227ea have promising application. Miscibility of these refrigerants with lubricants has a large influence on working effect of the refrigerating system. For this reason, an experimental apparatus for testing miscibility of new refrigerants with lubricants was established based on standard SH/T 0699—2000. The miscibility values of promising refrigerants RE170 and mixed refrigerant RE170/R227ea with a mineral oil were studied. RE170 and the mineral oil were completely miscible at−50℃, as oil proportion changed from 10%to 60%. When R227ea mass fraction in mixed refrigerant RE170/R227ea changed from 35% to 60% and oil proportion was specified at 14.6%±0.5%, low phase separation temperature increased with increasing R227ea. When R227ea mass fraction was below 38%, the mixed refrigerant and mineral oil became miscible even at−50℃. When R227ea mass fraction was over 55%, the mixed refrigerant and mineral oil were immiscible even at room temperature. Finally, by combining the methods of empirical equation and solubility parameter, a new evaluation method was proposed to evaluate the miscibility of pure refrigerants and binary refrigerant mixtures with the mineral oil.%随着制冷剂R22逐步淘汰,RE170、RE170/R227ea新型环保制冷剂有应用前景,其和润滑油能否互溶直接影响制冷系统的使用效果。根据标准SH/T 0699—2000建立了一套制冷剂和润滑油的互溶性测试系统,对RE170、RE170/R227ea和矿物油的互溶性进行了试验研究。结果表明:RE170的矿物油溶液在含油率为10%~60%时,当温度低至−50℃时没有出现分层或絮状物,二者互溶性非常好;混合制冷剂RE170/R227ea的矿物油溶液在含油率为14.6%±0.5%的基准情况下,当R227ea的质量分数在35%~60%变动时RE170/R227ea和矿物油的低温两相分离温度随R227ea含量增加而

  3. 78 FR 37231 - Guidance for Industry; Guidance on Abbreviated New Drug Applications: Stability Testing of Drug...

    Science.gov (United States)

    2013-06-20

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry; Guidance on Abbreviated New Drug... the availability of a guidance for industry entitled ``ANDAs: Stability Testing of Drug Substances and... generic drug review, FDA is recommending that the generic drug industry follow the approach in...

  4. Guidance for evidence-informed policies about health systems: rationale for and challenges of guidance development.

    Directory of Open Access Journals (Sweden)

    Xavier Bosch-Capblanch

    Full Text Available In the first paper in a three-part series on health systems guidance, Xavier Bosch-Capblanch and colleagues examine how guidance is currently formulated in low- and middle-income countries, and the challenges to developing such guidance.

  5. Guidance for performing preliminary assessments under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1991-09-01

    EPA headquarters and a national site assessment workgroup produced this guidance for Regional, State, and contractor staff who manage or perform preliminary assessments (PAs). EPA has focused this guidance on the types of sites and site conditions most commonly encountered. The PA approach described in this guidance is generally applicable to a wide variety of sites. However, because of the variability among sites, the amount of information available, and the level of investigative effort required, it is not possible to provide guidance that is equally applicable to all sites. PA investigators should recognize this and be aware that variation from this guidance may be necessary for some sites, particularly for PAs performed at Federal facilities, PAs conducted under EPA`s Environmental Priorities Initiative (EPI), and PAs at sites that have previously been extensively investigated by EPA or others. The purpose of this guidance is to provide instructions for conducting a PA and reporting results. This guidance discusses the information required to evaluate a site and how to obtain it, how to score a site, and reporting requirements. This document also provides guidelines and instruction on PA evaluation, scoring, and the use of standard PA scoresheets. The overall goal of this guidance is to assist PA investigators in conducting high-quality assessments that result in correct site screening or further action recommendations on a nationally consistent basis.

  6. Driving change : sustainable development action plans Guidance

    OpenAIRE

    Sustainable Development Commission

    2008-01-01

    This guidance builds upon the Sustainable Development Commission’s previous guidance, Getting Started (August 2005), which set out the basic elements that the Sustainable Development Commission would expect to see in a good Sustainable Development Action Plan. Publisher PDF Original published August 2005.

  7. Minimum variation guidance laws for interceptor missiles

    NARCIS (Netherlands)

    Weiss, M.; Shima, T.

    2014-01-01

    This paper introduces a new approach to guidance law design using linear quadratic optimal control theory, minimizing throughout the engagement the variation of the control input as well as the integral control effort. The guidance law is derived for arbitrary order missile dynamics and target maneu

  8. Career Guidance and Public Mental Health

    Science.gov (United States)

    Robertson, Peter J.

    2013-01-01

    Career guidance may have the potential to promote public health by contributing positively to both the prevention of mental health conditions and to population level well-being. The policy implications of this possibility have received little attention. Career guidance agencies are well placed to reach key target groups. Producing persuasive…

  9. 75 FR 53023 - Sound Incentive Compensation Guidance

    Science.gov (United States)

    2010-08-30

    ... principles and the guidance are consistent with the Principles for Sound Compensation Practices adopted by... of Management and Budget (OMB) for review, as required by the Paperwork Reduction Act. Today, OTS is.... Description: The guidance is based on three key principles that are designed to ensure that incentive...

  10. Driving change : sustainable development action plans Guidance

    OpenAIRE

    Sustainable Development Commission

    2008-01-01

    This guidance builds upon the Sustainable Development Commission’s previous guidance, Getting Started (August 2005), which set out the basic elements that the Sustainable Development Commission would expect to see in a good Sustainable Development Action Plan. Publisher PDF Original published August 2005.

  11. Anti-inflammation activity of sinomenine-induced autophagy in EA.hy926 cells%盐酸青藤碱诱导EA.hy926细胞自噬及其在抗炎中的作用

    Institute of Scientific and Technical Information of China (English)

    杨亭; 倪振洪; 龚薇; 何凤田

    2013-01-01

    Objective To investigate the underlying mechanism of sinomenine,a traditional Chinese herb extract monomer,in inducing autophagy and its anti-inflammation activity in EA.hy926 cells.Methods Western blotting was taken to detect the expression of autophagic markers LC3 Ⅱ,ERK2,phosphorylation ERK2 and inflammatory cytokine HMGB1 in the EA.hy926 cells after the treatment of sinomenine at 50 or 100 μg/mL for 12 h.Acridine orange staining was used to observe the formation of acidic vesicular organelles in the cells by fluorescence microscopy.Results Western blotting revealed that the expression of LC3 Ⅱ(0.67 ± 0.05) and phosphorylation ERK2 (1.08 ± 0.05) were remarkably increased after the treatment of sinomenine at 100 μg/mL (P < 0.05).Autophagic vesicles were induced by sinomenine,while both LC3 Ⅱ and autophagic vesicles were partially decreased by ERK-specific inhibitor U0126 (P < 0.05).LPS-induced HMGB1 expression could be reduced by sinomenine,which was partially reversed by autophagy inhibitor CQ (P < 0.05).Conclusion It may be one of the mechanisms of anti-inflammation activity of sinomenine that can reduce HMGB1 by promoting autophagy through the ERK pathway in EA.hy926 cells.%目的 探讨中药单体提取物盐酸青藤碱诱导人内皮细胞EA.hy926自噬的机制及其在抗炎中发挥的作用.方法 Western blot检测分别以终浓度为50、100 μg/mL的盐酸青藤碱处理12 h后的EA.hy926细胞中自噬相关蛋白LC3Ⅱ、ERK2、磷酸化ERK2及炎症细胞因子HMGB1表达变化情况;荧光显微镜观察吖啶橙染色的经盐酸青藤碱诱导后EA.hy926细胞酸性小体变化情况.结果 经终浓度为50、100 μg/mL的盐酸青藤碱处理EA.hy926细胞后,与对照组比较,100 μg/mL的盐酸青藤碱可使自噬相关蛋白LC3Ⅱ表达(0.67±0.05)及ERK2的磷酸化水平(1.08 ±0.05)上调(P<0.05),ERK抑制剂U0126可使LC3Ⅱ表达下调(P<0.05)及EA.hy926细胞中酸性小体减少;盐酸青藤碱可抑制EA

  12. A novel guidance law using fast terminal sliding mode control with impact angle constraints.

    Science.gov (United States)

    Sun, Lianghua; Wang, Weihong; Yi, Ran; Xiong, Shaofeng

    2016-09-01

    This paper is concerned with the question of, for a missile interception with impact angle constraints, how to design a guidance law. Firstly, missile interception with impact angle constraints is modeled; secondly, a novel guidance law using fast terminal sliding mode control based on extended state observer is proposed to optimize the trajectory and time of interception; finally, for stationary targets, constant velocity targets and maneuvering targets, the guidance law and the stability of the closed loop system is analyzed and the stability of the closed loop system is analyzed, respectively. Simulation results show that when missile and target are on a collision course, the novel guidance law using fast terminal sliding mode control with extended state observer has more optimized trajectory and effectively reduces the time of interception which has a great significance in modern warfare.

  13. A novel biased proportional navigation guidance law for close approach phase

    Institute of Scientific and Technical Information of China (English)

    Su Wenshan; Yao Dangnai; Li Kebo; Chen Lei

    2016-01-01

    A novel biased proportional navigation guidance (BPNG) law is proposed for the close approach phase, which aims to make the spacecraft rendezvous with the target in specific relative range and direction. Firstly, in order to describe the special guidance requirements, the concept of zero effort miss vector is proposed and the dangerous area where there exists collision risk for safety consideration is defined. Secondly, the BPNG, which decouples the range control and direc-tion control, is designed in the line-of-sight (LOS) rotation coordinate system. The theoretical anal-ysis proves that BPNG meets guidance requirements quite well. Thirdly, for the consideration of fuel consumption, the optimal biased proportional navigation guidance (OBPNG) law is derived by solving the Schwartz inequality. Finally, simulation results show that BPNG is effective for the close approach with the ability of evading the dangerous area and OBPNG consumes less fuel compared with BPNG.

  14. 77 FR 33972 - Channel Spacing and Bandwidth Limitations for Certain Economic Area (EA)-based 800 MHz...

    Science.gov (United States)

    2012-06-08

    .... Further, pursuant to a request by Concepts to Operations, Inc. (CTO), we modify our original proposal to....'' 17. The Association of Public-Safety Communications Officials- International, Inc. (APCO) and CTO..., largely duplicative requirements on EA-based 800 MHz SMR licensees. 20. CTO urges us to adopt an...

  15. 77 FR 14855 - Notice of Availability and Request for Comment on the Draft Environmental Assessment (EA) for the...

    Science.gov (United States)

    2012-03-13

    ... include any construction activities. The Mojave Air and Space Port's existing infrastructure would be used... Assessment (EA) for the Launch and Reentry of SpaceShipTwo Reusable Suborbital Rockets at the Mojave Air and Space Port AGENCY: Federal Aviation Administration (FAA), lead Federal agency and United States...

  16. 76 FR 13078 - Airworthiness Directives; Eclipse Aerospace, Inc. Model EA500 Airplanes Equipped With a Pratt and...

    Science.gov (United States)

    2011-03-10

    ...-005-AD; Amendment 39-16631; AD 2011-06-06] RIN 2120-AA64 Airworthiness Directives; Eclipse Aerospace..., we issued AD 2008-24-07, amendment 39-15747 (73 FR 70866, November 24, 2008), for certain Eclipse Aviation Corporation (Eclipse) Model EA500 airplanes equipped with a Pratt and Whitney Canada, Corp....

  17. Accelerating growth of HFC-227ea (1,1,1,2,3,3,3-heptafluoropropane) in the atmosphere

    NARCIS (Netherlands)

    Laube, J.C.; Martinerie, P.; Witrant, E.; Brenninkmeijer, C.A.M.; Bolder, M.; Rockmann, T.; van der Veen, C; Sturges, W.T.

    2010-01-01

    We report the first measurements of 1,1,1,2,3,3,3-heptafluoropropane (HFC-227ea), a substitute for ozone depleting compounds, in air samples originating from remote regions of the atmosphere and present evidence for its accelerating growth. Observed mixing ratios ranged from below 0.01 ppt in deep f

  18. Mineral fertilizers improve the sensory quality of East African Highland bananas (Musa AAA-EA, cv. Kisansa)

    NARCIS (Netherlands)

    Taulya, G.; Asten, van P.J.A.; Nowakunda, K.; Kaddu-Mukasa, P.

    2010-01-01

    Some farmers in Uganda believe that fertilizers negatively affect the sensory attributes of cooking type bananas. This belief may hamper the adoption of fertilizers. To verify the validity of this belief, bunches (Musa AAA-EA, cv. ‘Kisansa’) from fertilized (i.e. N-P-K-Mg-Zn-S-B-Mo) and non-fertiliz

  19. 78 FR 54635 - Notice of Intent To Prepare an Environmental Impact Statement for EA-18G Growler Airfield...

    Science.gov (United States)

    2013-09-05

    ... to the DoN to identify specific issues or topics of environmental concern that the commenter believes... Department of the Navy Notice of Intent To Prepare an Environmental Impact Statement for EA-18G Growler... National Environmental Policy Act (NEPA) of 1969, as implemented by the Council on Environmental...

  20. Mineral fertilizers improve the sensory quality of East African Highland bananas (Musa AAA-EA, cv. Kisansa)

    NARCIS (Netherlands)

    Taulya, G.; Asten, van P.J.A.; Nowakunda, K.; Kaddu-Mukasa, P.

    2010-01-01

    Some farmers in Uganda believe that fertilizers negatively affect the sensory attributes of cooking type bananas. This belief may hamper the adoption of fertilizers. To verify the validity of this belief, bunches (Musa AAA-EA, cv. ‘Kisansa’) from fertilized (i.e. N-P-K-Mg-Zn-S-B-Mo) and

  1. Space shuttle guidance, navigation, and control design equations. Volume 3: Guidance

    Science.gov (United States)

    1973-01-01

    Space shuttle guidance, navigation, and control design equations are presented. The space-shuttle mission includes three relatively distinct guidance phases which are discussed; atmospheric boost, which is characterized by an adaptive guidance law; extra-atmospheric activities; and re-entry activities, where aerodynamic surfaces are the principal effectors. Guidance tasks include pre-maneuver targeting and powered flight guidance, where powered flight is defined to include the application of aerodynamic forces as well as thruster forces. A flow chart which follows guidance activities throughout the mission from the pre-launch phase through touchdown is presented. The main guidance programs and subroutines used in each phase of a typical rendezvous mission are listed. Detailed software requirements are also presented.

  2. The origin, evolution, and current status of student guidance competencies in the United States = Origen, evolución y estado actual de las competencias de orientación educativa en EE. UU.

    OpenAIRE

    Gysbers, Norman C.; Henderson, Patricia

    2003-01-01

    The authors provide an exposition of the origin, evolution, and current status of student guidance competencies as a part of comprehensive guidance programs in the United States. The ways in which student guidance competencies are selected, organized, and delivered are described. Finally, examples of how student mastery of guidance competencies is being assessed are presented. El artículo presenta el origen, la evolución y el estado de la cuestión respecto a las competencias orientadoras a...

  3. Guidance law with impact time and impact angle constraints

    Institute of Scientific and Technical Information of China (English)

    Zhang Youan; Ma Guoxin; Liu Aili

    2013-01-01

    A novel closed-form guidance law with impact time and impact angle constraints is proposed for salvo attack of anti-ship missiles,which employs missile's normal acceleration (not jerk) as the control command directly.Firstly,the impact time control problem is formulated as tracking the designated time-to-go (the difference between the designated impact time and the current flight time) for the actual time-to-go of missile,and the impact angle control problem is formulated as tracking the designated heading angle for the actual heading angle of missile.Secondly,a biased proportional navigation guidance (BPNG) law with designated heading angle constraint is constructed,and the actual time-to-go estimation for this BPNG is derived analytically by solving the system differential equations.Thirdly,by adding a feedback control to this constructed BPNG to eliminate the time-to-go error-the difference between the standard time-to-go and the actual time-to-go,a guidance law with adjustable coefficients to control the impact time and impact angle simultaneously is developed.Finally,simulation results demonstrate the performance and feasibility of the proposed approach.

  4. A semi-analytical guidance algorithm for autonomous landing

    Science.gov (United States)

    Lunghi, Paolo; Lavagna, Michèle; Armellin, Roberto

    2015-06-01

    One of the main challenges posed by the next space systems generation is the high level of autonomy they will require. Hazard Detection and Avoidance is a key technology in this context. An adaptive guidance algorithm for landing that updates the trajectory to the surface by means of an optimal control problem solving is here presented. A semi-analytical approach is proposed. The trajectory is expressed in a polynomial form of minimum order to satisfy a set of boundary constraints derived from initial and final states and attitude requirements. By imposing boundary conditions, a fully determined guidance profile is obtained, function of a restricted set of parameters. The guidance computation is reduced to the determination of these parameters in order to satisfy path constraints and other additional constraints not implicitly satisfied by the polynomial formulation. The algorithm is applied to two different scenarios, a lunar landing and an asteroidal landing, to highlight its general validity. An extensive Monte Carlo test campaign is conducted to verify the versatility of the algorithm in realistic cases, by the introduction of attitude control systems, thrust modulation, and navigation errors. The proposed approach proved to be flexible and accurate, granting a precision of a few meters at touchdown.

  5. Optofluidic control of axonal guidance

    Science.gov (United States)

    Gu, Ling; Ordonez, Simon; Black, Bryan; Mohanty, Samarendra K.

    2013-03-01

    Significant efforts are being made for control on axonal guidance due to its importance in nerve regeneration and in the formation of functional neuronal circuitry in-vitro. These include several physical (topographic modification, optical force, and electric field), chemical (surface functionalization cues) and hybrid (electro-chemical, photochemical etc) methods. Here, we report comparison of the effect of linear flow versus microfluidic flow produced by an opticallydriven micromotor in guiding retinal ganglion axons. A circularly polarized laser tweezers was used to hold, position and spin birefringent calcite particle near growth cone, which in turn resulted in microfluidic flow. The flow rate and resulting shear-force on axons could be controlled by a varying the power of the laser tweezers beam. The calcite particles were placed separately in one chamber and single particle was transported through microfluidic channel to another chamber containing the retina explant. In presence of flow, the turning of axons was found to strongly correlate with the direction of flow. Turning angle as high as 90° was achieved. Optofluidic-manipulation can be applied to other types of mammalian neurons and also can be extended to stimulate mechano-sensing neurons.

  6. Augmented Reality Repair Guidance System

    Directory of Open Access Journals (Sweden)

    Sidharth Bhatia

    2012-07-01

    Full Text Available The daily life of a common man revolves around various forms of appliances/gadgets he uses throughout the day such as a mobile phone, laptop, printer, microwave oven, washing machine, etc. Although these appliances/gadgets are taken by most of the people for granted, the problem occurs when any of these things do not work as they are expected to. Getting them to the repair shops for every small glitch is expensive as well as time consuming. Although most of the companies which produce these appliances/gadgets do supply them with basic manuals, which deal with how to solve these minor issues, but reading them and at the same time repairing the corresponding appliance/gadget can be a frustrating task at times. These problems can be reduced to a large extent if some kind of live guidance is available. In this paper we propose a method to do so with the help of an augmented reality based system that will guide the user to carry out small scale repair jobs on these gadgets. All that is required is a decent webcam and a computing device, with a processor of 1 GHz or more and a display screen.

  7. Surface-water interface induces conformational changes critical for protein adsorption: Implications for monolayer formation of EAS hydrophobin

    Directory of Open Access Journals (Sweden)

    Kamron eLey

    2015-11-01

    Full Text Available The class I hydrophobin EAS is part of a family of small, amphiphilic fungal proteins best known for their ability to self-assemble into stable monolayers that modify the hydrophobicity of a surface to facilitate further microbial growth. These proteins have attracted increasing attention for industrial and biomedical applications, with the aim of designing surfaces that have the potential to maintain their clean state by resisting non-specific protein binding. To gain a better understanding of this process, we have employed all-atom molecular dynamics to study initial stages of the spontaneous adsorption of monomeric EAS hydrophobin on fully hydroxylated silica, a commonly used industrial and biomedical substrate. Particular interest has been paid to the Cys3-Cys4 loop, which has been shown to exhibit disruptive behavior in solution, and the Cys7-Cys8 loop, which is believed to be involved in the aggregation of EAS hydrophobin at interfaces. Specific and water mediated interactions with the surface were also analyzed. We have identified two possible binding motifs, one which allows unfolding of the Cys7-Cys8 loop due to the surfactant-like behavior of the Cys3-Cys4 loop, and another which has limited unfolding due to the Cys3-Cys4 loop remaining disordered in solution. We have also identified intermittent interactions with water which mediate the protein adsorption to the surface, as well as longer lasting interactions which control the diffusion of water around the adsorption site. These results have shown that EAS behaves in a similar way at the air-water and surface-water interfaces, and have also highlighted the need for hydrophilic ligand functionalization of the silica surface in order to prevent the adsorption of EAS hydrophobin.

  8. Spectral Analysis, Synthesis, & Energy Distributions of Nearby E+A Galaxies Using SDSS-IV MaNGA

    Science.gov (United States)

    Weaver, Olivia A.; Anderson, Miguel Ricardo; Wally, Muhammad; James, Olivia; Falcone, Julia; Liu, Allen; Wallack, Nicole; Liu, Charles; SDSS Collaboration

    2017-01-01

    Utilizing data from the Mapping Nearby Galaxies at APO (MaNGA) Survey (MaNGA Product Launch-4, or MPL-4), of the latest generation of the Sloan Digital Sky Survey (SDSS-IV), we identified nine post-starburst (E+A) systems that lie within the Green Valley transition zone. We identify the E+A galaxies by their SDSS single fiber spectrum and u-r color, then confirmed their classification as post-starburst by coding/plotting methods and spectral synthesis codes (FIREFLY and PIPE3D), as well as with their Spectral Energy Distributions (SEDs) from 0.15 µm to 22 µm, using GALEX, SDSS, 2MASS, and WISE data. We produced maps of gaussian-fitted fluxes, equivalent widths, stellar velocities, metallicities and age. We also produced spectral line ratio diagrams to classify regions of stellar populations of the galaxies. We found that our sample of E+As retain their post-starburst properties across the entire galaxy, not just at their center. We detected matching a trend line in the ultraviolet and optical bands, consistent with the expected SEDs for an E+A galaxy, and also through the J, H and Ks bands, except for one object. We classified one of the nine galaxies as a luminous infrared galaxy, unusual for a post-starburst object. Our group seeks to further study stellar population properties, spectral energy distributions and quenching properties in E+A galaxies, and investigate their role in galaxy evolution as a whole. This work was supported by the Alfred P. Sloan Foundation via the SDSS-IV Faculty and Student Team (FAST) initiative, ARC Agreement #SSP483 to the CUNY College of Staten Island. This work was also supported by grants to The American Museum of Natural History, and the CUNY College of Staten Island through from National Science Foundation.

  9. An approximate atmospheric guidance law for aeroassisted plane change maneuvers

    Science.gov (United States)

    Speyer, Jason L.; Crues, Edwin Z.

    1988-01-01

    An approximate optimal guidance law for the aeroassisted plane change problem is presented which is based upon an expansion of the Hamilton-Jacobi-Bellman equation with respect to the small parameter of Breakwell et al. (1985). The present law maximizes the final velocity of the reentry vehicle while meeting terminal constraints on altitude, flight path angle, and heading angle. The integrable zeroth-order solution found when the small parameter is set to zero corresponds to a solution of the problem where the aerodynamic forces dominate the inertial forces. Higher order solutions in the expansion are obtained from the solution of linear partial differential equations requiring only quadrature integration.

  10. 78 FR 54949 - Major Project Financial Plan Guidance

    Science.gov (United States)

    2013-09-06

    ... TRANSPORTATION Federal Highway Administration Major Project Financial Plan Guidance AGENCY: Federal Highway... Major Project Financial Plan Guidance outlining the procedures the FHWA will follow when reviewing and approving Financial Plans. The proposed Major Project Financial Plan Guidance incorporates changes required...

  11. The experimental cascade curves of EAS at E sub 0 10(17) eV obtained by the method of detection of Cherenkov pulse shape

    Science.gov (United States)

    Fomin, Y. A.; Kalmykov, G. B.; Khristiansen, M. V.; Motova, M. V.; Nechin, Y. A.; Prosin, V. V.; Zhukov, V. Y.; Efimov, N. N.; Grigoriev, V. M.; Nikiforova, E. S.

    1985-01-01

    The individual cascade curves of EAS with E sub 0 10 to the 17th power eV/I to 3/ were studied by detection of EAS Cherenkov light pulses. The scintillators located at the center of the Yakutsk EAS array within a 500-m radius circle were used to select the showers and to determine the main EAS parameters. The individual cascade curves N(t) were obtained using the EAS Cherenkov light pulses satisfying the following requirements: (1) the signal-to-noise ratio fm/delta sub n 15, (2) the EAS axis-detector distance tau sub 350 m, (3) the zenith angle theta 30 deg, (4) the probability for EAS to be detected by scintillators W 0.8. Condition (1) arises from the desire to reduce the amplitude distortion of Cherenkov pulses due to noise and determines the range of EAS sizes, N(t). The resolution times of the Cherenkov pulse shape detectors are tau sub 0 approx. 23 ns which results in distortion of a pulse during the process of the detection. The distortion of pulses due to the finiteness of tau sub 0 value was estimated. It is shown that the rise time of pulse becomes greater as tau sub 0.5/tau sub 0 ratio decreases.

  12. A Multi-Level Investigation into the Antecedents of Enterprise Architecture (EA) Assimilation in the U.S. Federal Government: A Longitudinal Mixed Methods Research Study

    Science.gov (United States)

    Makiya, George K.

    2012-01-01

    This dissertation reports on a multi-dimensional longitudinal investigation of the factors that influence Enterprise Architecture (EA) diffusion and assimilation within the U.S. federal government. The study uses publicly available datasets of 123 U.S. federal departments and agencies, as well as interview data among CIOs and EA managers within…

  13. A Multi-Level Investigation into the Antecedents of Enterprise Architecture (EA) Assimilation in the U.S. Federal Government: A Longitudinal Mixed Methods Research Study

    Science.gov (United States)

    Makiya, George K.

    2012-01-01

    This dissertation reports on a multi-dimensional longitudinal investigation of the factors that influence Enterprise Architecture (EA) diffusion and assimilation within the U.S. federal government. The study uses publicly available datasets of 123 U.S. federal departments and agencies, as well as interview data among CIOs and EA managers within…

  14. EA-MC Neutronic Calculations on IAEA ADS Benchmark 3.2

    Energy Technology Data Exchange (ETDEWEB)

    Dahlfors, Marcus [Uppsala Univ. (Sweden). Dept. of Radiation Sciences; Kadi, Yacine [CERN, Geneva (Switzerland). Emerging Energy Technologies

    2006-01-15

    The neutronics and the transmutation properties of the IAEA ADS benchmark 3.2 setup, the 'Yalina' experiment or ISTC project B-70, have been studied through an extensive amount of 3-D Monte Carlo calculations at CERN. The simulations were performed with the state-of-the-art computer code package EA-MC, developed at CERN. The calculational approach is outlined and the results are presented in accordance with the guidelines given in the benchmark description. A variety of experimental conditions and parameters are examined; three different fuel rod configurations and three types of neutron sources are applied to the system. Reactivity change effects introduced by removal of fuel rods in both central and peripheral positions are also computed. Irradiation samples located in a total of 8 geometrical positions are examined. Calculations of capture reaction rates in {sup 129}I, {sup 237}Np and {sup 243}Am samples and of fission reaction rates in {sup 235}U, {sup 237}Np and {sup 243}Am samples are presented. Simulated neutron flux densities and energy spectra as well as spectral indices inside experimental channels are also given according to benchmark specifications. Two different nuclear data libraries, JAR-95 and JENDL-3.2, are applied for the calculations.

  15. Future Small x Physics with ep and eA Colliders

    CERN Document Server

    Frankfurt, L L; Frankfurt, Leonid; Strikman, Mark

    1999-01-01

    The interaction of spatially small dipoles with nucleons, nuclei is calculated in the DGLAP approximation at the top of HERA energies and found to be close to the $S$-channel unitarity limit in the case of the color octet dipoles. The DGLAP analyses of the current diffractive data appear to support this conclusion as they indicate a $\\sim 30-40%$ probability of the gluon induced diffraction for $Q^2\\sim 4 $GeV$^2$. The need for the high-precision measurements of the $t$-dependence of inclusive and exclusive diffraction for pinpointing higher twist effects in the gluon sector is emphasized.The $eA$ collisions at HERA would provide a strong amplification of the gluon densities allowing to reach deep into the regime of nonlinear QCD evolution. Connection between the leading twist nuclear shadowing and leading twist diffraction in $ep$ scattering is explained. The presented model independent results for the nuclear shadowing for light nuclei indicate much larger shadowing for the gluon sector than for the sea qua...

  16. A New Parallel Processing Scheme Enabling Full Monte Carlo EAS Simulation in the GZK Energy Region

    Science.gov (United States)

    Kasahara, K.; Cohen, F.

    We developed a new parallel processing method enabling full M.C EAS simulation (say, with minimum energy of 500 keV) without using thin sampling even at 1019 eV. Normally, distributed-parallel processing needs a specific software and programs must be organized to match with such system. During the computation such a scheme also requires complex communications among many computer hosts. Our scheme first creates a skeleton of a shower, and smashes it into n-peaces and distributes the peaces to n- cpu to flesh them. After each peace is completely fleshed, they are assembled to make a complete picture of the shower. Thus, during the computation need no communication. With n=50, a 1019 eV shower can be simulated in ~10 days. For a 1020 eV shower, we may randomly sample a fraction of n-peases (say, 100 for n=1000), and safely econstruct whole picture of the shower. The scheme dose not use any weight on each particle and very much stable. The scheme has been implemented in Cosmos code. To produce a number of showers with full fluctuations, we have also developed a new method which utilizes the present result. The latter is used for the TA experiment and is described in an accompanying paper.

  17. Array for measurement of the EAS pulse temporal structure at distances R>500 m

    Science.gov (United States)

    Fernandez, Arturo

    Indications of the existence of temporal structure in the signals of Extensive Air Showers (EAS) of energies 10 greater than 17 eV at core distances of about 500 m (Atrashkevich et al ,1997, J.Phys.G, Nucl. Part. Phys., v.23,p. 237 and papers cited there) and the preliminary analysis of the Auger Water Cherenkov Detector (WCD) signal traces (Fernandez et al, this conference) stimulated us to intensify the temporal signal studies. For this aim we started to construct a hybrid array of one WCD plus an array of seven Air Cherenkov Detectors (ACD) one near the WCD and six in a regular hexagonal network centered on the WCD. Separation between ACDs is of about 750 m. The correlation in the temporal structure of the WCD signals and the position of the maximum obtained from the ACD array is studied. This hybrid array is located at the campus of the University of Puebla which is inside the city. Evidence that such an array can be successfully used to detect EASs with 10 primary energies above 16 eV in conditions of moderate to heavy light pollution environment such as the city of Puebla is presented.

  18. Extensive Air Shower Array at the University of Puebla (EAS-BUAP)

    Science.gov (United States)

    Salazar, H.; Martinez, O.; Moreno, E.; Cotzomi, J.; Villaseñor, L.

    2003-06-01

    We describe the design and operation of the first stage of the EAS-UAP extensive air shower array, as a detector of very high energy cosmic rays (1016 > Eo > 1014eV). The array is located at the Campus of Puebla University. It consist of 18 liquid scintillator detectors, with an active surface of 1 m2 each and a detector spacing of 20 m in a square grid. One Auger Water Cherenkov detector is also included as part of the array. In this report we discuss the stability, the calibration, the arrival direction and lateral distribution function reconstruction capabilities of the detector array, as derived from the 10 detectors in operation in the first stage. Our results shows that the angular accuracy in arrival direction is less than 5.5° in the range from 20° to 60°. The measurements in the Water Cherenkov Detector show us the possibility to separete electromagnetic and muon component. The main characteristics of the array allow us also to use it as educational and training facility.

  19. Guidance of magnetic space tug

    Science.gov (United States)

    Fabacher, Emilien; Lizy-Destrez, Stéphanie; Alazard, Daniel; Ankersen, Finn; Profizi, Alexandre

    2017-07-01

    Magnetic tugging of a target satellite without thrust capacity can be interesting in various contexts, as for example End-Of-Life management, or to complete launchers capabilities. The aim is to gradually modify the orbit of the target by constantly exerting on it a magnetic force. To do so, the chaser is assumed equipped with a steerable magnetic dipole, able to create both forces and torques on the magnetic torque rods carried by the target. The chaser is also supposed to carry electric thrusters, creating a continuous force which modifies the orbit of the whole formation composed of chaser and target. The relative motions of both satellites are derived, in order to assess the feasibility of such a concept. Relative configuration (attitudes and position) trajectories are derived, which are compliant with the dynamics, and enable the chaser to tug the target. Considering targets in Low Earth Orbit (LEO), the magnetic field of the Earth is taken into account, modeled by the International Geomagnetic Reference Field (IGRF). The position of the magnetic torque rod of the target may not be located at its center of mass. This lever-arm is taken into account in the dynamics. As for every Electro-Magnetic Formation Flight concept developed in the literature, satellites involved in magnetic tugging are constantly subjected to torques, created by the Earth magnetic field and by the magnetic fields created by the other satellites in the formation. In this study, the solution chosen to face this problem is to take into account the attitude equilibrium of the satellites early in the guidance phase, in order to avoid having to wave the dipole, as it is generally done. Promising results are presented for different types of orbit, showing that the concept could be feasible in many different scenarios.

  20. Significant Guidance Issued by the Federal Highway Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  1. Significant Guidance Issued by the Federal Aviation Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  2. Significant Guidance Issued by the Federal Transit Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  3. Significant Guidance Issued by the Federal Motor Carrier Safety Administration

    Data.gov (United States)

    Department of Transportation — A list of Significant Guidance documents, which include guidance document disseminated to regulated entities or the general public that may reasonably be anticipated...

  4. Ultrasound guidance system for prostate biopsy

    Science.gov (United States)

    Hummel, Johann; Kerschner, Reinhard; Kaar, Marcus; Birkfellner, Wolfgang; Figl, Michael

    2017-03-01

    We designed a guidance system for prostate biopsy based on PET/MR images and 3D ultrasound (US). With our proposed method common inter-modal MR-US (or CT-US in case of PET/CTs) registration can be replaced by an intra-modal 3D/3D-US/US registration and an optical tracking system (OTS). On the pre-operative site, a PET/MR calibration allows to link both hybrid modalities with an abdominal 3D-US. On the interventional site, another abdominal 3D US is taken to merge the pre-operative images with the real-time 3D-US via 3D/3D-US/US registration. Finally, the images of a tracked trans-rectal US probe can be displayed with the pre-operative images by overlay. For PET/MR image fusion we applied a point-to-point registration between PET and OTS and MR and OTS, respectively. 3D/3D-US/US registration was evaluated for images taken in supine and lateral patient position. To enable table shifts between PET/MR and US image acquisition a table calibration procedure is presented. We found fiducial registration errors of 0.9 mm and 2.8 mm, respectively, with respect to the MR and PET calibration. A target registration error between MR and 3D US amounted to 1.4 mm. The registration error for the 3D/3D-US/US registration was found to be 3.7 mm. Furthermore, we have shown that ultrasound is applicable in an MR environment.

  5. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Gurney, Kevin R

    2015-01-12

    This document constitutes the final report under DOE grant DE-FG-08ER64649. The organization of this document is as follows: first, I will review the original scope of the proposed research. Second, I will present the current draft of a paper nearing submission to Nature Climate Change on the initial results of this funded effort. Finally, I will present the last phase of the research under this grant which has supported a Ph.D. student. To that end, I will present the graduate student’s proposed research, a portion of which is completed and reflected in the paper nearing submission. This final work phase will be completed in the next 12 months. This final workphase will likely result in 1-2 additional publications and we consider the results (as exemplified by the current paper) high quality. The continuing results will acknowledge the funding provided by DOE grant DE-FG-08ER64649.

  6. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    DeTar, Carleton [P.I.

    2012-12-10

    This document constitutes the Final Report for award DE-FC02-06ER41446 as required by the Office of Science. It summarizes accomplishments and provides copies of scientific publications with significant contribution from this award.

  7. Quasi-steady flight to quasi-steady flight transition in a windshear - Trajectory optimization and guidance

    Science.gov (United States)

    Miele, A.; Wang, T.; Melvin, W. W.

    1987-01-01

    The near-optimum guidance of an aircraft from quasi-steady flight to quasi-steady flight in a windshear is studied. The take-off problem is considered with reference to flight in a vertical plane; allowance is made for the presence of a downdraft as well as horizontal shear. It is assumed that the power setting is held at the maximum value and that the aircraft is controlled through the angle of attack. While the shear guidance and the initial aftershear guidance use constant gain coefficients, the final aftershear guidance employs a variable gain coefficient. The results show that the guidance scheme for quasi-steady flight recovery yields a transition from quasi-steady flight to quasi-steady flight which is close to that of the optimal trajectory; it guarantees the restoration of the initial quasi-steady state and has good stability properties.

  8. “Into the dwelling of the hermit”: Imaginative Space in E.A. Poe’s The Fall of the House of Usher

    Directory of Open Access Journals (Sweden)

    Jana Speth

    2011-07-01

    Full Text Available L’article analyse, à l’aide de notions tirées de la psychologie cognitive, tels que les “scripts”, les “concepts” et la “transformation mentale”, la tendance naturelle du lecteur à la construction de sens, c’est-à-dire son aptitude à inférer par l’imagination les informations manquantes d’une architecture imaginaire lacunaire donnée. La narration La chute de la maison d’Usher de E.A. Poe, grâce à une mise en abyme, évoque deux réalités imaginaires différentes qui finalement chutent pour faire place à un seul espace focalisé. Les méthodes de Poe qui stimulent la construction des espaces imaginaires aussi bien que leur déconstruction seront analysées avec les outils que nous fournit la neuropsychologie.A hermit lives in complete seclusion from the outer world, and the fictional hermit in E.A. Poe’s narrative enjoys the twofold seclusion of a doubly imaginative space constructed by the reader. Only the deconstruction of the mise en abyme, along with its superordinate fictional space – carefully staged by the author and executed by the reader – poses a threat to his existence, and will finally lead to The Fall of the House of Usher.El artículo analiza con ayuda de nociones extraídas de la psicología cognitiva, como los “scripts”, los “conceptos” y la “transformación mental”, la tendencia natural del lector a construir sentido, es decir, su aptitud para inferir mediante la imaginación las informaciones ausentes en una determinada arquitectura imaginaria y de carácter fragmentario. La narración La caída de la casa Usher, gracias a una mise en abyme, evoca dos realidades imaginarias diferentes que finalmente caen para dar lugar a un único espacio focalizado. Los métodos de Poe que estimulan la construcción de espacios imaginarios tanto como su deconstrucción serán analizados con los instrumentos que nos proporciona la neuropsicología.

  9. Integrated Entry Guidance for Reusable Launch Vehicle

    Institute of Scientific and Technical Information of China (English)

    NING Guo-dong; ZHANG Shu-guang; FANG Zhen-ping

    2007-01-01

    A method for the implementation of integrated three-degree-of-freedom constrained entry guidance for reusable launch vehicle is presented. Given any feasible entry conditions, terminal area energy management interface conditions, and the reference trajectory generated onboard then, the method can generate a longitudinal guidance profile rapidly, featuring linear quadratic regular method and a proportional-integral-derivative tracking law with time-varying gains, which satisfies all the entry corridor constraints and meets the requirements with high precision. Afterwards, by utilizing special features of crossrange parameter, establishing bank-reversal corridor,and determining bank-reversals according to dynamically adjusted method, the algorithm enables the lateral entry guidance system to fly a wide range of missions and provides reliable and good performance in the presence of significant aerodynamic modeling uncertainty.Fast trajectory guidance profiles and simulations with a reusable launch vehicle model for various missions and aerodynamic uncertainties are presented to demonstrate the capacity and reliability of this method.

  10. Optimal guidance for the space shuttle transition

    Science.gov (United States)

    Stengel, R. F.

    1974-01-01

    A guidance method for the space shuttle's transition from hypersonic entry to subsonic cruising flight is presented. The method evolves from a numerical trajectory optimization technique in which kinetic energy and total energy (per unit weight) replace velocity and time in the dynamic equations. This allows the open end-time problem to be transformed to one of fixed terminal energy. In its ultimate form, E-Guidance obtains energy balance (including dynamic-pressure-rate damping) and path length control by angle-of-attack modulation and cross-range control by roll angle modulation. The guidance functions also form the basis for a pilot display of instantaneous maneuver limits and destination. Numerical results illustrate the E-Guidance concept and the optimal trajectories on which it is based.

  11. RCRA Programmatic Information Policy and Guidance

    Data.gov (United States)

    U.S. Environmental Protection Agency — This asset includes program policy and guidance documents that are used by the EPA regions, states, tribes and private parties to implement the hazardous waste...

  12. Tests and Guidance: What Students Need.

    Science.gov (United States)

    Krumboltz, John D.

    1982-01-01

    Innovations in testing and guidance which can integrate assessment to facilitate learning, help develop practical wisdom in behavior, and correct students' faulty cognitions in career decisions are described. (CM)

  13. Beyond Black: An Alternative to Ethnocentric Guidance

    Science.gov (United States)

    Goldman, Robert C.

    1977-01-01

    This article is a clarification of the author's personal philosophy in the guidance and counseling of youth and adults, and clarification of commonalities that form the raison d'etre of all student personnel services. (Author)

  14. Much more than just another guidance document.

    Science.gov (United States)

    Kulkarni, K

    2016-11-01

    As a pediatric hematologist oncologist with clinical and research interests in thrombosis in high-risk pediatric populations, and also as a member of the ISTH Early Career Task Force, I had the opportunity to develop a guidance document on 'Thromboprophylaxis for central venous catheters in the pediatric population' for the 'Guidelines and Guidance Documents' committee. In this communication, I share my experiences to date; I discuss my excitement and initial success, the steep learning curve required to build research acumen, the lessons learnt, and the opportunities and challenges faced. My experience with preparing the guidance document was much more than writing 'just another guidance document'. © 2016 International Society on Thrombosis and Haemostasis.

  15. ROUTE PLAN DESIGNER FOR TRACTOR GUIDANCE SYSTEMS

    DEFF Research Database (Denmark)

    Sveistrup, Daniel; Jørgensen, Rasmus Nyholm; Green, Ole

    2010-01-01

    Earlier works have shown field trial designs to be very labor extensive, even when combining autoguidancesystems with conventional machinery.Designing routes for semi-automated systems in a controlled manner is both resource demandingand complicated. Different types of auto-guidance systems vary...... was outlined, it took less thanone hour entering the design into the software and generating the auto-guidance files.KeywordsGIS, Auto steering systems, plot trial design, full-scale field trials, Java...

  16. Ergonomic concerns with lightbar guidance displays.

    Science.gov (United States)

    Ima, C S; Mann, D D

    2004-05-01

    This article reviews some ergonomic factors associated with agricultural guidance displays. Any technology or management decision that improves the efficiency of an agricultural operation can be considered an aspect of precision farming. Agricultural guidance displays are one such tool because they help to reduce guidance error (i.e., skipping and overlapping of implements within the field), which result in improper application of crop inputs at increased cost. Although each of the guidance displays currently available functions using a different principle, their key objective is to communicate useful guidance information to the operator of the agricultural machine. The case with which the operator obtains the required information depends on a number of ergonomic factors, such as color perceptibility, flash rate, attentional demand, display size, viewing distance, and height of placement of the display in the cab. Ergonomics can be defined as the application of knowledge to create a safe, comfortable, and effective work environment. Consequently, it is critical to consider ergonomics when designing guidance displays or when locating a display in the tractor cab. Without considering ergonomics, it is unlikely that the efficiency of the human-machine system can be optimized.

  17. 75 FR 49913 - Draft Guidance, “Federal Greenhouse Gas Accounting and Reporting”

    Science.gov (United States)

    2010-08-16

    ..., Energy, and Economic Performance (74 FR 52117) in order to establish an integrated strategy toward... QUALITY Draft Guidance, ``Federal Greenhouse Gas Accounting and Reporting'' AGENCY: Council on... and accounting procedures. On April 5, 2010, DOE-FEMP submitted the final recommendations on...

  18. Blind range influence on guidance loop performance: An adjoint-based analysis

    NARCIS (Netherlands)

    Bucco, D.; Weiss, M.

    2013-01-01

    In this paper, we investigate the use of adjoint simulation for assessing the miss distance performance of a generic guidance system under the influence of a blind range condition. The term "blind range" refers to that final portion of the missile trajectory for which sensor data are not available.

  19. [Evolution of the social autonomy scale (EAS) in schizophrenic patients depending on their management].

    Science.gov (United States)

    Leguay, D; Rouillon, F; Azorin, J-M; Gasquet, I; Loze, J-Y; Arnaud, R; Dillenschneider, A

    2010-10-01

    It is becoming clear to clinicians that functional prognosis is the issue that should be guiding their choice of therapeutic strategy offered to people with schizophrenic disorders. An individual's degree of social autonomy is one of the principal factors determining functional prognosis, and it has become essential to identify the variables that influence it. The ESPASS survey was set up to follow a cohort of 6000 schizophrenic patients in a naturalistic setting, and was conducted over six months by 1170 psychiatrists. Patients were required to meet DSM-IV TR criteria for schizophrenia, with the exception of those suffering from an acute psychotic episode, and to either need a change in their antipsychotic treatment or its initiation. Data collected included patients' sociodemographical characteristics, types of treatment (pharmacological and non-pharmacological), illness characteristics (as determined by the DSM-IV TR criteria), degree of social autonomy (EAS), effectiveness (IAQ scale), overall severity of the illness (CGI - S scale) and patient satisfaction with medical treatment (PASAP self-questionnaire). Concerning the non-pharmacological aspects of treatment that offer patients programmes to increase their autonomy, the survey made it possible to collect data describing real practices and to measure the actual availability of rehabilitation services. It has been verified that the sample of psychiatrists included in this survey, as well as the schizophrenic patients under evaluation, were representative of the French psychiatrist and patient populations. Most importantly, the survey made it possible to objectively evaluate the healthcare services available in France. It seems that the vast majority of public-service psychiatrists have access to hospital and ambulatory facilities for treatment (medical-psychological centers, day-care hospitals and rest centers), as well as access to facilities providing simulated real-life activities. Psychiatrists who are

  20. Two particular EA-type binaries in the globular cluster ω Centauri

    Institute of Scientific and Technical Information of China (English)

    Kai Li; Sheng-Bang Qian

    2013-01-01

    We analyzed the B and V light curves of two EA-type binaries V211 and NV358 for the first time using the Wilson-Devinney code.Our analysis shows that V211 is a typical Algol-type binary and NV358 is a well detached binary system.As the two binaries are definite members of ω Centauri due to their proper motion,we estimated their physical parameters,obtaining M1 =1.13 ± 0.03 M⊙,R1 =0.98 ± 0.01 R⊙,M2 =0.33 ± 0.01 M⊙ and R2 =0.92 ± 0.01 R⊙ for V211;M1 =1.30±0.05 M⊙,R1 =1.03±0.01 R⊙,M2 =0.58±0.02 M⊙ and R2 =0.78±0.01 R⊙ for NV358.On the color-magnitude diagram of ω Centauri,V211 is located in the faint blue straggler region and its primary component is more massive than a star at the main-sequence turnoff.Therefore,V211 is a blue straggler and was formed by mass transfer from the secondary component to the primary.The age of NV358is less than 1.93 Gyr,indicating that it is much younger than the first generation of stars in ω Centauri.Like NV364 in ω Centauri,NV358 should be a second-generation binary.

  1. EstratÃgias de Aprendizagem de InglÃs como LÃngua Estrangeira em EaD.

    OpenAIRE

    Francisco TarcÃzio Cavalcante Benevides Junior

    2012-01-01

    Esta pesquisa tem como objetivo estudar as estratÃgias de aprendizagem (EA) utilizadas por aprendizes de inglÃs como lÃngua estrangeira em EaD. Adotamos a conceituaÃÃo de Oxford (1990), de acordo com a qual estratÃgias sÃo ―passos tomados pelo aluno para melhorar o prÃprio aprendizado‖. As estratÃgias agrupam-se em dois grandes conjuntos â o das diretas e o das indiretas, que se subdividem em: estratÃgias de memÃria; de compensaÃÃo; estratÃgias cognitivas; metacognitivas; afetivas...

  2. Liminality in cultural transition: applying ID-EA to advance a concept into theory-based practice.

    Science.gov (United States)

    Baird, Martha B; Reed, Pamela G

    2015-01-01

    As global migration increases worldwide, nursing interventions are needed to address the effects of migration on health. The concept of liminality emerged as a pivotal concept in the situation-specific theory of well-being in refugee women experiencing cultural transition. As a relatively new concept in the discipline of nursing, liminality is explored using a method, called ID-EA, which we developed to advance a theoretical concept for application to nursing practice. Liminality in the context of cultural transition is further developed using the five steps of inquiry of the ID-EA method. The five steps are as follows: (1) inductive inquiry: qualitative research, (2) deductive inquiry: literature review, (3) synthesis of inductive and deductive inquiry, (4) evaluation inquiry, and (5) application-to-practice inquiry. The overall goal of this particular work was to develop situation-specific, theory-based interventions that facilitate cultural transitions for immigrants and refugees.

  3. A robust and high precision optimal explicit guidance scheme for solid motor propelled launch vehicles with thrust and drag uncertainty

    Science.gov (United States)

    Maity, Arnab; Padhi, Radhakant; Mallaram, Sanjeev; Mallikarjuna Rao, G.; Manickavasagam, M.

    2016-10-01

    A new nonlinear optimal and explicit guidance law is presented in this paper for launch vehicles propelled by solid motors. It can ensure very high terminal precision despite not having the exact knowledge of the thrust-time curve apriori. This was motivated from using it for a carrier launch vehicle in a hypersonic mission, which demands an extremely narrow terminal accuracy window for the launch vehicle for successful initiation of operation of the hypersonic vehicle. The proposed explicit guidance scheme, which computes the optimal guidance command online, ensures the required stringent final conditions with high precision at the injection point. A key feature of the proposed guidance law is an innovative extension of the recently developed model predictive static programming guidance with flexible final time. A penalty function approach is also followed to meet the input and output inequality constraints throughout the vehicle trajectory. In this paper, the guidance law has been successfully validated from nonlinear six degree-of-freedom simulation studies by designing an inner-loop autopilot as well, which enhances confidence of its usefulness significantly. In addition to excellent nominal results, the proposed guidance has been found to have good robustness for perturbed cases as well.

  4. Autonomous and cooperative multi-UAV guidance in adversarial environment

    Science.gov (United States)

    Zengin, Ugur

    The research presented in this dissertation is aimed at developing rule-based autonomous and cooperative guidance strategies for UAVs to perform missions such as path planning, target tracking and rendezvous while reducing their risk/threat exposure level, and avoiding threats and/or obstacles by utilizing measurement information provided by sensors. First, a mathematical formulation is developed to represent the area of operation that contains various types of threats, obstacles, and restricted areas, in a single framework. Once constructed, there will be no need to distinguish between threats, obstacles and restricted areas as the framework already contains the information on what needs to be avoided and the level of penalty for a given position in the area. This framework provides the mathematical foundation for the guidance strategies to make intelligent decisions during the execution of the mission and also provides scalar metrics to assess the performance of a guidance strategy in a given mission. The autonomous guidance strategies are developed by using a rule-based expert system approach with the requirements of completing assigned mission or task, avoiding obstacle/restricted-areas, minimizing threat exposure level, considering the dynamic and communication constraints of the UAVs and avoiding collision. All these requirements and objectives are quantified and prioritized to facilitate the development of guidance algorithms that can be executed in real-time. The strategies consist of a set of "decision states", which contain rules to determine how the host UAV should move by generating heading and speed signals. Cooperation of multiple UAVs is modeled by minimizing a cost function, which is constructed based on the level of threat exposure for each UAV and distance of each UAV relative to the target. This improves the performance of the system in the terms of increasing the total area of coverage of the sensors onboard the UAVs, increasing the flexibility

  5. Structural, thermal and optical properties of Cu$^{2+}$ doped methacrylic acid–ethyl acrylate (MAA:EA) copolymer films

    Indian Academy of Sciences (India)

    Y MADHAVA KUMAR; N O GOPAL; Ch RAMU; S BABU; J LAKSHMANA RAO; H NAGABHUSHANA; S C SHARMA

    2017-09-01

    Pure and Cu$^{2+}$ doped methacrylic acid–ethyl acrylate (MAA:EA) copolymer films were prepared using thesolution cast technique. The amorphous feature of the copolymer was depicted using X-ray diffraction scans and degreeof crystallinity was found to vary with increasing doping content. UV–Vis absorption spectra in the wavelength region200–900 nm were used to evaluate the optical properties like direct band gap, indirect band gap and absorption edge. Theoptical band gap decreased with the increase of mol% of Cu$^{2+}$ ions. Fourier transform infrared spectral studies on pureMAA:EA and Cu$^{2+}$ ions-doped films revealed the vibrational changes that occurred due to the effect of dopant salt inthe copolymer. Thermal properties of these films were investigated by employing differential scanning calorimetry andthermogravimetric analysis. The variation in film morphology was examined by scanning electron microscopy. Electronparamagnetic resonance (EPR) spectra of all the doped samples exhibited signals due to Cu2+ ions with the effective$g$-values $g_{\\parallel} = 2.177$ and $g_{\\perp} = 2.058$. The observed variation in the EPR signal intensity is due to the isolated and aggregated copper ions. The photoluminescence spectra of Cu$^{2+}$ ions-doped MAA:EA copolymer exhibited four emissionpeaks at 480 (blue), 579 (yellow), 604 (red) and 671nm (red).

  6. Resistin impairs glucose permeability in EA.hy926 cells by down-regulating GLUT1 expression.

    Science.gov (United States)

    Li, Qiang; Cai, Yuxi; Huang, Jing; Yu, Xiaolan; Sun, Jun; Yang, Zaiqing; Zhou, Lei

    2016-10-15

    Type 2 diabetes mellitus (T2DM) is a chronic disease which is now affecting the health of more and more people in the world. Resistin, discovered in 2001, is considered to be closely related to metabolic dysfunction and obesity. Previous study showed that hyperglycemia is always accompanied by a high serum resistin concentration. We therefore investigated whether resistin can mediate glucose transfer across the blood-tissue barrier. Here, we employed a transwell system to analyze glucose permeability in EA.hy926 human endothelial cells treated without or with human resistin. In EA.hy926 cells treated with resistin, the permeability to glucose was heavily impaired. This was due to the down-regulation of GLUT1 expression as a result of the treatment, rather than regulation of tight junctions. In addition, overexpression of GLUT1 in EA.hy926 cells was able to recover the blocking effect of resistin on glucose permeability. We further found that resistin could inhibit the expression of peroxisome proliferator-activated receptor gamma (PPARγ) and consequently impede the transcription of GLUT1. The results of the present study suggested that resistin could cause glucose retention in serum and thus result in hyperglycemia. This provides a novel explanation for hyperglycemia and a potential new way of treating type 2 diabetes mellitus. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. Study of the muon content of very high-energy EAS measured with the KASCADE-Grande observatory

    CERN Document Server

    Arteaga-Velazquez, J C; Bekk, K; Bertaina, M; Bluemer, J; Bozdog, H; Brancus, I M; Cantoni, E; Chiavassa, A; Cossavella, F; Curcio, C; Daumiller, K; de Souza, V; Di Pierro, F; Doll, P; Engel, R; Engler, J; Fuchs, B; Fuhrmann, D; Gils, H J; Glasstetter, R; Grupen, C; Haungs, A; Heck, D; Hoerandel, J R; Huber, D; Huege, T; Kampert, K -H; Kang, D; Klages, H O; Link, K; Luczak, P; Ludwig, M; Mathes, H J; Mayer, H J; Melissas, M; Milke, J; Mitrica, B; Morello, C; Oehlschlaeger, J; Ostapchenko, S; Palmieri, N; Petcu, M; Pierog, T; Rebel, H; Roth, M; Schieler, H; Schoo, S; Schroeder, F G; Sima, O; Toma, G; Trinchero, G C; Ulrich, H; Weindl, A; Wochele, D; Wochele, J

    2013-01-01

    The KASCADE-Grande detector is an air-shower array devoted to the study of primary cosmic rays with very high-energies (E = 10^{16} - 10^{18} eV). The instrument is composed of different particle detector systems suitable for the detailed study of the properties of Extensive Air Showers (EAS) developed by cosmic rays in the atmosphere. Among the EAS observables studied with the detector, the charged number of particles, the muon content (at different energy thresholds), and the number of electrons are found. By comparing the measurements of these air-shower parameters with the expectations from MC simulations, different hadronic interaction models can be tested at the high-energy regime with the KASCADE-Grande experiment. In this work, the results of a study on the evolution of the muon content of EAS with zenith angle, performed with the KASCADE-Grande instrument, is presented. Measurements are compared with predictions from MC simulations based on the QGSJET II, QGSJET II-04, SIBYLL 2.1 and EPOS 1.99 hadron...

  8. The Development of a Lifelong Guidance System in Hungary

    Science.gov (United States)

    Watts, A. G.; Borbely-Pecze, Bors Tibor

    2011-01-01

    The development of a lifelong guidance system in Hungary Systematic work is currently being undertaken in Hungary to develop a lifelong guidance system, in line with principles outlined by leading international organisations. The origins of career guidance in Hungary, and the nature of the current career guidance system, are outlined. The main…

  9. The voice of users in adult career guidance

    DEFF Research Database (Denmark)

    Plant, Peter

    2012-01-01

    Is the voice of users heard in adult career guidance? Pan-Nordic Research shows that users are seen as recipients rather than agents i adult career guidance.......Is the voice of users heard in adult career guidance? Pan-Nordic Research shows that users are seen as recipients rather than agents i adult career guidance....

  10. Constituent Aspects of Workplace Guidance in Secondary VET

    Science.gov (United States)

    Swager, Robert; Klarus, Ruud; van Merriënboer, Jeroen J. G.; Nieuwenhuis, Loek F. M.

    2015-01-01

    Purpose: This paper aims to present an integrated model of workplace guidance to enhance awareness of what constitutes good guidance, to improve workplace guidance practices in vocational education and training. Design/methodology/approach: To identify constituent aspects of workplace guidance, a systematic search of Web of Science was conducted,…

  11. The voice of users in adult career guidance

    DEFF Research Database (Denmark)

    Plant, Peter

    2012-01-01

    Is the voice of users heard in adult career guidance? Pan-Nordic Research shows that users are seen as recipients rather than agents i adult career guidance.......Is the voice of users heard in adult career guidance? Pan-Nordic Research shows that users are seen as recipients rather than agents i adult career guidance....

  12. Non-Participation in Guidance: An Opportunity for Development?

    Science.gov (United States)

    Thomsen, Rie

    2014-01-01

    This article discusses how new opportunities for guidance can emerge from an analysis of the interplay between the participation (or lack of participation) of the individuals in career guidance, and the career guidance practitioner's response. The article suggests critical psychology as a framework for career guidance research and presents…

  13. The Development of a Lifelong Guidance System in Hungary

    Science.gov (United States)

    Watts, A. G.; Borbely-Pecze, Bors Tibor

    2011-01-01

    The development of a lifelong guidance system in Hungary Systematic work is currently being undertaken in Hungary to develop a lifelong guidance system, in line with principles outlined by leading international organisations. The origins of career guidance in Hungary, and the nature of the current career guidance system, are outlined. The main…

  14. Final Report

    DEFF Research Database (Denmark)

    Heiselberg, Per; Brohus, Henrik; Nielsen, Peter V.

    This final report for the Hybrid Ventilation Centre at Aalborg University describes the activities and research achievement in the project period from August 2001 to August 2006. The report summarises the work performed and the results achieved with reference to articles and reports published...

  15. Raising the Profile of Career Guidance: Educational and Vocational Guidance Practitioner

    Science.gov (United States)

    Hiebert, Bryan

    2009-01-01

    In 2007 the International Association for Educational and Vocational Guidance (IAEVG) launched the Educational and Vocational Guidance Practitioner credential (EVGP) as one means of formally acknowledging the knowledge, skills, and personal attributes that practitioners need in order to provide quality career development services to clients. This…

  16. A New Concept for Atmospheric Reentry Optimal Guidance: An Inverse Problem Inspired Approach

    Directory of Open Access Journals (Sweden)

    Davood Abbasi

    2013-01-01

    Full Text Available This paper presents a new concept for atmospheric reentry online optimal guidance and control using a method called MARE G&C that exploits the different time scale featured by reentry dynamics. The new technique reaches a quasi-analytical solution and simplified computations, even considering both lift-to-drag ratio and aerodynamic roll as control variables; in addition, the paper offers a solution for the challenging path constraints issue, getting inspiration from the inverse problem methodology. The final resulting algorithm seems suitable for onboard predictive guidance, a new need for future space missions.

  17. Safety of magnetic fusion facilities: Guidance

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    This document provides guidance for the implementation of the requirements identified in DOE-STD-6002-96, Safety of Magnetic Fusion Facilities: Requirements. This guidance is intended for the managers, designers, operators, and other personnel with safety responsibilities for facilities designated as magnetic fusion facilities. While the requirements in DOE-STD-6002-96 are generally applicable to a wide range of fusion facilities, this Standard, DOE-STD-6003-96, is concerned mainly with the implementation of those requirements in large facilities such as the International Thermonuclear Experimental Reactor (ITER). Using a risk-based prioritization, the concepts presented here may also be applied to other magnetic fusion facilities. This Standard is oriented toward regulation in the Department of Energy (DOE) environment as opposed to regulation by other regulatory agencies. As the need for guidance involving other types of fusion facilities or other regulatory environments emerges, additional guidance volumes should be prepared. The concepts, processes, and recommendations set forth here are for guidance only. They will contribute to safety at magnetic fusion facilities.

  18. Guidance Trade-off for Aerocapture Missions

    Science.gov (United States)

    Vernis, P.; Gelly, G.; Ferreira, E.; da Costa, R.; Ortega, G.

    In the very late 90's, EADS-ST began home funded studies on aerocapture problems. The objectives of these studies were at that time to prepare a possible cooperation within the NASA/Cnes MSR-Orbiter program by investigating this new orbital insertion technique studying different algorithmic solutions from a guidance point of view. According to these preliminary studies, EADS-ST was retained in 2002 by ESA to study insertion techniques such as aerocapture, aero-gravity assist or aerobraking techniques within the frame of Technological Research Program able to bring solutions to Aurora program. In the frame of the ATPE (Aeroassist Technologies for Planetary Exploration) TRP program, EADS-ST, led by Astrium-Gmbh (now part of EADS-ST), developed and implemented an efficient and simple guidance scheme able to cope with mission requirements for aerocapture on Mars, Venus or the Earth: the Feedback Trajectory Control, or FTC. The development of this guidance scheme was made according to a preliminary trade-off analysis using different guidance schemes. Among those ones was an original predictor-corrector guidance scheme, already analyzed within the frame of the MSR-O mission. But, the FTC algoritm was prefered because of its good results and high simplicity. This paper presents an upgrade of the original Apoapsis Predictor, or AP, with the improvement of its robustness woth respect to off-nomonal flight conditions and its process simplification. A new trade-off analysis is then detailed on a Mars Sample return mission.

  19. Measuring Integrated Socioemotional Guidance at School: Factor Structure and Reliability of the Socioemotional Guidance Questionnaire (SEG-Q)

    Science.gov (United States)

    Jacobs, Karen; Struyf, Elke

    2013-01-01

    Socioemotional guidance of students has recently become an integral part of education, however no instrument exists to measure integrated socioemotional guidance. This study therefore examines the factor structure and reliability of the Socioemotional Guidance Questionnaire. Psychometric properties of the Socioemotional Guidance Questionnaire and…

  20. 78 FR 48201 - Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2013-01; Guidance for...

    Science.gov (United States)

    2013-08-07

    ... COMMISSION Japan Lessons-Learned Project Directorate Interim Staff Guidance JLD-ISG-2013-01; Guidance for... Lessons-Learned Project Directorate Interim Staff Guidance (JLD-ISG), JLD-ISG-2013-01, ``Guidance for... to http://www.nrc.gov/reading-rm/doc-collections/isg/japan-lessons-learned.html and refer to...

  1. E2C(R2) Periodic Benefit-Risk Evaluation Report and E2C(R2) Periodic Benefit-Risk Evaluation Report--Questions and Answers; International Council for Harmonisation; Guidances for Industry; Availability. Notice.

    Science.gov (United States)

    2016-07-19

    The Food and Drug Administration (FDA or Agency) is announcing the availability of guidances for industry entitled ``E2C(R2) Periodic Benefit-Risk Evaluation'' (E2C(R2) guidance) and ``E2C(R2) Periodic Benefit-Risk Evaluation Report--Questions and Answers'' (E2C(R2) Q&A guidance). These guidances were prepared under the auspices of the International Council for Harmonisation (ICH), formerly the International Conference on Harmonisation. The E2C(R2) draft guidance, issued April 11, 2012, updated and combined two ICH guidances, ``E2C Clinical Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (E2C guidance) and ``Addendum to E2C Clinical Safety Data Management: Periodic Safety Update Reports for Marketed Drugs'' (addendum to the E2C guidance). The E2C(R2) guidance is intended to describe the format, content, and timing of a Periodic Benefit-Risk Evaluation Report (PBRER) for an approved drug or biologic, and it finalizes the draft guidance. The E2C(R2) Q&A guidance is a supplementary guidance that is intended to clarify key issues in the E2C(R2) guidance.

  2. Recent results from the Yakutsk experiment: The development of EAS and the energy spectrum and primary particle mass composition in the energy region of 10{sup 15}-10{sup 19} eV

    Energy Technology Data Exchange (ETDEWEB)

    Knurenko, S.P. [Yu. G. Shafer Institute for Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Ivanov, A.A.; Pravdin, M.P.; Sabourov, A.V.; Sleptsov, I.Ye

    2008-01-15

    Experimental data obtained at the Yakutsk array after the modernization in 1993 are analyzed. The characteristics of EAS longitudinal and radial development found from the charged particle flux and EAS Cerenkov light registered at the Yakutsk array complex are presented. The energy spectrum of EAS obtained from Cerenkov light and an estimate of the mass composition of primary cosmic rays are presented.

  3. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Stinis, Panos [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-08-07

    This is the final report for the work conducted at the University of Minnesota (during the period 12/01/12-09/18/14) by PI Panos Stinis as part of the "Collaboratory on Mathematics for Mesoscopic Modeling of Materials" (CM4). CM4 is a multi-institution DOE-funded project whose aim is to conduct basic and applied research in the emerging field of mesoscopic modeling of materials.

  4. Human Genetic Disorders of Axon Guidance

    Science.gov (United States)

    Engle, Elizabeth C.

    2010-01-01

    This article reviews symptoms and signs of aberrant axon connectivity in humans, and summarizes major human genetic disorders that result, or have been proposed to result, from defective axon guidance. These include corpus callosum agenesis, L1 syndrome, Joubert syndrome and related disorders, horizontal gaze palsy with progressive scoliosis, Kallmann syndrome, albinism, congenital fibrosis of the extraocular muscles type 1, Duane retraction syndrome, and pontine tegmental cap dysplasia. Genes mutated in these disorders can encode axon growth cone ligands and receptors, downstream signaling molecules, and axon transport motors, as well as proteins without currently recognized roles in axon guidance. Advances in neuroimaging and genetic techniques have the potential to rapidly expand this field, and it is feasible that axon guidance disorders will soon be recognized as a new and significant category of human neurodevelopmental disorders. PMID:20300212

  5. Ultrastructural changes in the membrane system of isolated chloroplasts of spinach under the influence of carbonic anhydrase inhibitors AA and EA

    Directory of Open Access Journals (Sweden)

    Marina V. Vodka

    2013-04-01

    Full Text Available The effects of carbonic anhydrase inhibitors (АА and EA on the membrane system of isolated chloroplasts of spinach were investigated. Under the influence of AA the considerable alterations in granal structure occurred, the thickness of the granal thylakoids increased by 36% and the interspace between thylakoids by 10% comparable with the control. As a result of EA treatment, the thickness of granal thylakoids enhanced by 31% and the interspace between thylakoids increased by 8% in comparison to the control. It was shown that structure of the granal system of the chloroplast was more sensitive to AA than EA. The data obtained can indicate a decrease in the activity of the thylakoid carbonic anhydrase, inhibition of electron transport and photosynthetic process as a whole in the presence of carbonic anhydrase inhibitors (AA and EA.

  6. Characteristics of EAS and primary particle mass composition in the energy region of 10{sup 17}-3.10{sup 19} eV by Yakutsk data

    Energy Technology Data Exchange (ETDEWEB)

    Knurenko, S.P. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Egorova, V.P. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Ivanov, A.A. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Kolosov, V.A. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Makarov, I.T. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Petrov, Z.E. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Sleptsov, I.Ye. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation); Struchkov, G.G. [Yu.G. Shafer Institute of Cosmophysical Research and Aeronomy, 31 Lenin Ave., 677980 Yakutsk (Russian Federation)

    2006-01-15

    In this work the data of the Yakutsk complex EAS array and their comparison with calculation in the case of primary nuclei of different chemical elements are presented. The calculation by QGSJET model have been used interpreting experimental data.

  7. Aerospace plane guidance using geometric control theory

    Science.gov (United States)

    Van Buren, Mark A.; Mease, Kenneth D.

    1990-01-01

    A reduced-order method employing decomposition, based on time-scale separation, of the 4-D state space in a 2-D slow manifold and a family of 2-D fast manifolds is shown to provide an excellent approximation to the full-order minimum-fuel ascent trajectory. Near-optimal guidance is obtained by tracking the reduced-order trajectory. The tracking problem is solved as regulation problems on the family of fast manifolds, using the exact linearization methodology from nonlinear geometric control theory. The validity of the overall guidance approach is indicated by simulation.

  8. Active evacuation guidance using sensor agent robot

    Science.gov (United States)

    Ise, Daiki; Mita, Akira

    2012-04-01

    Evacuation systems for buildings are designed based on event scenarios, so they are not prepared for unexpected events that are not included in the scenarios. In this paper, we propose a new active evacuation guidance system using sensor agent robots. We first introduce a Structural Health Monitoring (SHM) system to be used in conjunction with sensor agent robots for active evacuation guidance. Then the role of sensor agent robots is explained. An algorithm to immediately access the safety of the building after a large earthquake is also proposed using only the information taken by a sensor agent robot.

  9. Virtual Ultrasound Guidance for Inexperienced Operators

    Science.gov (United States)

    Caine, Timothy; Martin, David

    2012-01-01

    Medical ultrasound or echocardiographic studies are highly operator-dependent and generally require lengthy training and internship to perfect. To obtain quality echocardiographic images in remote environments, such as on-orbit, remote guidance of studies has been employed. This technique involves minimal training for the user, coupled with remote guidance from an expert. When real-time communication or expert guidance is not available, a more autonomous system of guiding an inexperienced operator through an ultrasound study is needed. One example would be missions beyond low Earth orbit in which the time delay inherent with communication will make remote guidance impractical. The Virtual Ultrasound Guidance system is a combination of hardware and software. The hardware portion includes, but is not limited to, video glasses that allow hands-free, full-screen viewing. The glasses also allow the operator a substantial field of view below the glasses to view and operate the ultrasound system. The software is a comprehensive video program designed to guide an inexperienced operator through a detailed ultrasound or echocardiographic study without extensive training or guidance from the ground. The program contains a detailed description using video and audio to demonstrate equipment controls, ergonomics of scanning, study protocol, and scanning guidance, including recovery from sub-optimal images. The components used in the initial validation of the system include an Apple iPod Classic third-generation as the video source, and Myvue video glasses. Initially, the program prompts the operator to power-up the ultrasound and position the patient. The operator would put on the video glasses and attach them to the video source. After turning on both devices and the ultrasound system, the audio-video guidance would then instruct on patient positioning and scanning techniques. A detailed scanning protocol follows with descriptions and reference video of each view along with

  10. A Multiconstrained Ascent Guidance Method for Solid Rocket-Powered Launch Vehicles

    Directory of Open Access Journals (Sweden)

    Si-Yuan Chen

    2016-01-01

    Full Text Available This study proposes a multiconstrained ascent guidance method for a solid rocket-powered launch vehicle, which uses a hypersonic glide vehicle (HGV as payload and shuts off by fuel exhaustion. First, pseudospectral method is used to analyze the two-stage launch vehicle ascent trajectory with different rocket ignition modes. Then, constraints, such as terminal height, velocity, flight path angle, and angle of attack, are converted into the constraints within height-time profile according to the second-stage rocket flight characteristics. The closed-loop guidance method is inferred by different spline curves given the different terminal constraints. Afterwards, a thrust bias energy management strategy is proposed to waste the excess energy of the solid rocket. Finally, the proposed method is verified through nominal and dispersion simulations. The simulation results show excellent applicability and robustness of this method, which can provide a valuable reference for the ascent guidance of solid rocket-powered launch vehicles.

  11. A guidance and navigation system for continuous low thrust vehicles. M.S. Thesis

    Science.gov (United States)

    Tse, C. J. C.

    1973-01-01

    A midcourse guidance and navigation system for continuous low thrust vehicles is described. A set of orbit elements, known as the equinoctial elements, are selected as the state variables. The uncertainties are modelled statistically by random vector and stochastic processes. The motion of the vehicle and the measurements are described by nonlinear stochastic differential and difference equations respectively. A minimum time nominal trajectory is defined and the equation of motion and the measurement equation are linearized about this nominal trajectory. An exponential cost criterion is constructed and a linear feedback guidance law is derived to control the thrusting direction of the engine. Using this guidance law, the vehicle will fly in a trajectory neighboring the nominal trajectory. The extended Kalman filter is used for state estimation. Finally a short mission using this system is simulated. The results indicate that this system is very efficient for short missions.

  12. The Alterations of IL-1Beta, IL-6, and TGF-Beta Levels in Hippocampal CA3 Region of Chronic Restraint Stress Rats after Electroacupuncture (EA) Pretreatment

    OpenAIRE

    Tianwei Guo; Zhuo Guo; Xinjing Yang; Lan Sun; Sihan Wang; A. Yingge; Xiaotian He; Tu Ya

    2014-01-01

    Immunological reactions induced by proinflammatory cytokines have been involved in the pathogenesis of depressive disorders. Recent studies showed that Electroacupuncture (EA) was able to reduce depressive symptoms; however, the underlying mechanism and its potential targets remain unknown. In the present study, we used a 21-day chronic restraint stress rats as a model to investigate how EA could alleviate depression. Open field test was carried out to evaluate the depressive symptoms at sel...

  13. P(EA-MAn-APTES)/二氧化硅有机无机杂化材料的合成和表征%Synthesis and characterization of hybrid organic-inorganic materials based on EA-Man-APTES and silica

    Institute of Scientific and Technical Information of China (English)

    邱凤仙; 周钰明; 刘举正; 张旭苹

    2005-01-01

    采用γ氨丙基三乙氧基硅烷 (APTES)作为偶联剂,以丙烯酸乙酯(EA)、顺丁烯二酸酐(MAn)和正硅酸乙酯(TEOS)为原料,通过自由基溶液聚合和溶胶凝胶过程制得了P(EA-MAn-APTES)/二氧化硅有机无机杂化材料,其中TEOS的质量分数从0变化至25%.利用傅立叶红外(FT-IR)光谱、溶胶抽取、扫描电子显微镜(SEM)、透射电子显微镜(TEM)、示差扫描量热法(DSC)和热重分析(TGA)性能测试装置对材料的结构、凝胶含量、表面形貌、粒子大小和热性能进行了表征.结果表明:有机相与无机相之间是以共价键结合的,杂化材料中凝胶的含量较高,聚合物基体中SiO2是纳米复合的,具有较好的分散性和热稳定性.%Poly (EA-Man-APTES)/silica hybrid materials were successfully prepared from Ethyl acrylate (EA),maleic anhydride (Man) and tetraethoxysilane (TEOS) in the presence of a coupling agent 3-aminopropyltriethoxysilane (APTES),by free-radical solution polymerization and in situ sol-gel process.The mass fraction of TEOS varied from 0 to 25%.The hybrid materials were characterized by the methods of FT-IR spectra,solvent extraction,scanning electron microscope (SEM),transmission electron microscope (TEM),differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) measuring apparatus to get their structures,gel contents,morphologies,particle sizes and thermal performances.The results show that the covalent bonds are between organic and inorganic phases,gel contents in the hybrid materials are much higher,the SiO2 phase is well dispersed in the polymer matrix,silicon dioxide exist at nanoscale in the composites and have excellent thermal stability.

  14. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    R Paul Drake

    2004-01-12

    OAK-B135 This is the final report from the project Hydrodynamics by High-Energy-Density Plasma Flow and Hydrodynamics and Radiation Hydrodynamics with Astrophysical Applications. This project supported a group at the University of Michigan in the invention, design, performance, and analysis of experiments using high-energy-density research facilities. The experiments explored compressible nonlinear hydrodynamics, in particular at decelerating interfaces, and the radiation hydrodynamics of strong shock waves. It has application to supernovae, astrophysical jets, shock-cloud interactions, and radiative shock waves.

  15. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Jarillo-Herrero, Pablo [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2017-02-07

    This is the final report of our research program on electronic transport experiments on Topological Insulator (TI) devices, funded by the DOE Office of Basic Energy Sciences. TIbased electronic devices are attractive as platforms for spintronic applications, and for detection of emergent properties such as Majorana excitations , electron-hole condensates , and the topological magneto-electric effect . Most theoretical proposals envision geometries consisting of a planar TI device integrated with materials of distinctly different physical phases (such as ferromagnets and superconductors). Experimental realization of physics tied to the surface states is a challenge due to the ubiquitous presence of bulk carriers in most TI compounds as well as degradation during device fabrication.

  16. Terminal Multiple Surface Sliding Guidance for Planetary Landing: Development, Tuning and Optimization via Reinforcement Learning

    Science.gov (United States)

    Furfaro, Roberto; Wibben, Daniel R.; Gaudet, Brian; Simo, Jules

    2015-03-01

    The problem of achieving pinpoint landing accuracy in future space missions to planetary bodies such as the Moon or Mars presents many challenges, including the requirements of higher accuracy and degree of flexibility. These new challenges may require the development of a new class of guidance algorithms. In this paper, a nonlinear guidance algorithm for planetary landing is proposed and analyzed. Based on Higher-Order Sliding Control (HOSC) theory, the Multiple Sliding Surface Guidance (MSSG) algorithm has been specifically designed to take advantage of the ability of the system to reach multiple sliding surfaces in a finite time. As a result, a guidance law that is both globally stable and robust against unknown, but bounded perturbations is devised. The proposed MSSG does not require any off-line trajectory generation, but the acceleration command is instead generated directly as function of the current and final (target) state. However, after initial analysis, it has been noted that the performance of MSSG critically depends on the choice in guidance gains. MSSG-guided trajectories have been compared to an open-loop fuel-efficient solution to investigate the relationship between the MSSG fuel performance and the selection of the guidance parameters. A full study has been executed to investigate and tune the parameters of MSSG utilizing reinforcement learning in order to truly optimize the performance of the MSSG algorithm in powered descent scenarios. Results show that the MSSG algorithm can indeed generate closed-loop trajectories that come very close to the optimal solution in terms of fuel usage. A full comparison of the trajectories is included, as well as a further Monte Carlo analysis examining the guidance errors of the MSSG algorithm under perturbed conditions using the optimized set of parameters.

  17. Compact E+A Galaxies as a Progenitor of Massive Compact Quiescent Galaxies at 0.2

    CERN Document Server

    Zahid, H Jabran; Geller, Margaret J; Damjanov, Ivana; Chillingarian, Igor; Sohn, Jubee; Salmi, Fadia; Hwang, Ho Seong

    2016-01-01

    We search the Sloan Digital Sky Survey and the Baryon Oscillation Sky Survey to identify ~5500 massive compact quiescent galaxy candidates at 0.2E+A galaxies based on their spectral properties and make this catalog publicly available. We examine sizes, stellar population ages and kinematics of galaxies in the sample and show that the physical properties of compact E+A galaxies suggest that they are a progenitor of massive compact quiescent galaxies. Thus, two separate classes of objects-compact E+A and compact quiescent galaxies-may be linked by a common evolutionary sequence. The typical stellar population age of compact E+A galaxies is <1 Gyr. The existence of compact E+A galaxies with young stellar populations at 0.2E+A galaxies. Assuming passive evolution, we convert this number density into an app...

  18. The genome of the Erwinia amylovora phage PhiEaH1 reveals greater diversity and broadens the applicability of phages for the treatment of fire blight.

    Science.gov (United States)

    Meczker, Katalin; Dömötör, Dóra; Vass, János; Rákhely, Gábor; Schneider, György; Kovács, Tamás

    2014-01-01

    The enterobacterium Erwinia amylovora is the causal agent of fire blight. This study presents the analysis of the complete genome of phage PhiEaH1, isolated from the soil surrounding an E. amylovora-infected apple tree in Hungary. Its genome is 218 kb in size, containing 244 ORFs. PhiEaH1 is the second E. amylovora infecting phage from the Siphoviridae family whose complete genome sequence was determined. Beside PhiEaH2, PhiEaH1 is the other active component of Erwiphage, the first bacteriophage-based pesticide on the market against E. amylovora. Comparative genome analysis in this study has revealed that PhiEaH1 not only differs from the 10 formerly sequenced E. amylovora bacteriophages belonging to other phage families, but also from PhiEaH2. Sequencing of more Siphoviridae phage genomes might reveal further diversity, providing opportunities for the development of even more effective biological control agents, phage cocktails against Erwinia fire blight disease of commercial fruit crops.

  19. The Fundamental Planes of E+A galaxies and GALEX UV-excess early-type galaxies: Revealing their intimate connection

    CERN Document Server

    Choi, Yumi; Yoon, Suk-Jin

    2009-01-01

    Strong Balmer absorption lines and the lack of Ha and [OII] emission lines signify that E+As are post-starburst systems. Recent studies suggest that E+As may undergo the transition from the `blue cloud' to the `red sequence' and eventually migrate to red sequence ETGs. An observational validation of this scenario is to identify the intervening galaxy population between E+As and the red-sequence. Motivated by recent findings with GALEX that a large fraction of ETGs exhibit UV-excess as a sign of RSF, we investigate the possible connection of the UV-excess galaxies to E+As. In particular, we examine the FP scaling relations of the largest sample of ~1,000 E+As selected from the SDSS and ~20,000 morphologically-selected SDSS ETGs with GALEX UV data. The FP parameters, combined with stellar population indicators, reveal a certain group of UV-excess ETGs that bridges between E+As and quiescent red galaxies. The newly identified galaxies are the post-starburst systems characterized by UV-excess but no Ha emission. ...

  20. Radioactive waste from non-licensed activities - identification of waste, compilation of principles and guidance, and proposed system for final management; Radioaktivt avfall fraan icke tillstaandsbunden verksamhet (RAKET) - identifiering av aktuellt avfall, sammanstaellning av relevanta regler och principer, foerslag paa system foer omhaendertagande

    Energy Technology Data Exchange (ETDEWEB)

    Jones, C.; Pers, K. [Kemakta Konsult AB, Stockholm (Sweden)

    2001-07-01

    Presently national guidelines for the handling of radioactive waste from non-licensed activities are lacking in Sweden. Results and information presented in this report are intended to form a part of the basis for decisions on further work within the Swedish Radiation Protection Institute on regulations or other guidelines on final management and final disposal of this type of waste. An inventory of radioactive waste from non-licensed activities is presented in the report. In addition, existing rules and principles used in Sweden - and internationally - on the handling of radioactive and toxic waste and non-radioactive material are summarized. Based on these rules and principles a system is suggested for the final management of radioactive material from non-licensed activities. A model is shown for the estimation of dose as a consequence of leaching of radio-nuclides from different deposits. The model is applied on different types of waste, e.g. peat ashes, light concrete and low-level waste from a nuclear installation.

  1. Remedial Investigation/Feasibility Study (RI/FS) process, elements and techniques guidance

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-01

    This manual provides detailed guidance on Remedial Investigation/Feasibility Studies (RI/FSs) conducted pursuant to the Comprehensive Environmental Response, Compensation, and Liability Act (CERCLA) at Department of Energy (DOE) facilities. The purpose of the RI/FS, to assess the risk posed by a hazardous waste site and to determine the best way to reduce that risk, and its structure (site characterization, risk assessment, screening and detailed analysis of alternatives, etc.) is defined in the National Oil and Hazardous Substances Pollution Contingency Plan (NCP) and further explained in the Environmental Protection Agency`s (EPA`s) Guidance for Conducting Remedial Investigations and Feasibility Studies Under CERCLA (Interim Final) 540/G-89/004, OSWER Directive 9355.3-01, October 1988. Though issued in 1988, the EPA guidance remains an excellent source of information on the conduct and structure of an RI/FS. This document makes use of supplemental RI/FS-related guidance that EPA has developed since its initial document was issued in 1988, incorporates practical lessons learned in more than 12 years of experience in CERCLA hazardous site remediation, and drawing on those lessons, introduces the Streamlined Approach For Environmental Restoration (SAFER), developed by DOE as a way to proceed quickly and efficiently through the RI/FS process at DOE facilities. Thus as its title implies, this guidance is intended to describe in detail the process and component elements of an RI/FS, as well as techniques to manage the RI/FS effectively.

  2. Simulating an underwater vehicle self-correcting guidance system with Simulink

    Institute of Scientific and Technical Information of China (English)

    FAN Hui; ZHANGYu-wen; LI Wen-zhe

    2008-01-01

    Underwater vehicles have already adopted self-correcting directional guidance algorithms based on multi-beam self-guidance systems, not waiting for research to determine the most effective algorithms. The main challenges facing research on these guidance systems have been effective modeling of the guidance algorithm and a means to analyze the simulation results. A simulation structure based on Simulink that dealt with both issues was proposed. Initially, a mathematical model of relative motion between the vehicle and the target was developed, which was then encapsulated as a subsystem. Next,steps for constructing a model of the self-correcting guidance algorithm based on the Stateflow module were examined in detail. Finally, a 3-D model of the vehicle and target was created in VRML, and by processing mathematical results, the model was shown moving in a visual environment. This process gives more intuitive results for analyzing the simulation. The results showed that the simulation structure performs well. The simulation program heavily used modularization and encapsulation, so has broad applicability to simulations of other dynamic systems.

  3. Guidance for performing site inspections under CERCLA

    Energy Technology Data Exchange (ETDEWEB)

    1992-09-01

    This guidance presents EPA`s site inspection (SI) strategy. The strategy discusses procedural guidelines to investigate potential Superfund (CERCLA) sites for evaluation pursuant to the Hazard Ranking System (HRS), revised in accordance with the Superfund Amendments and Reauthorization Act of 1986. The HRS is the primary means by which EPA evaluates sites for superfund`s National Priorities List (NPL).

  4. Cannabinoid receptor CB2 modulates axon guidance

    DEFF Research Database (Denmark)

    Duff, Gabriel; Argaw, Anteneh; Cecyre, Bruno

    2013-01-01

    Navigation of retinal projections towards their targets is regulated by guidance molecules and growth cone transduction mechanisms. Here, we present in vitro and in vivo evidences that the cannabinoid receptor 2 (CB2R) is expressed along the retino-thalamic pathway and exerts a modulatory action ...

  5. Hypermedia Authoring with Writing Process Guidance

    Science.gov (United States)

    Chang, Kuo-En; Sung, Yao-Ting; Zheng, Jie-Wen

    2007-01-01

    A writing process of five stages, setting the topic and goals, planning the outline, organising the structure, building the content, and reviewing, is proposed to guide hypermedia authoring. To explore the effects of the system designed with writing-process guidance, this study enrolled 108 seventh graders at a junior high school as experimental…

  6. guidance and behaviour management in early childhood

    African Journals Online (AJOL)

    Elizabeth

    development and the general behaviour manifestation of children under the childcare ... given by care givers to infants in the pre-primary school classes). Guidance means an .... aids, such as films, recorders, video, TV., children play; ... Simulation and games: These are teaching techniques in which real life situations and ...

  7. MR Thermometry for guidance of thermal therapy

    NARCIS (Netherlands)

    Sprinkhuizen, S.M.

    2010-01-01

    The research described in this thesis has aimed to further investigate magnetic resonance (MR) thermometry (MRT) techniques as to become a reliable guidance tool for thermal therapy. The various physical processes allowing for temperature measurements based upon the MR signal are described. It is de

  8. The Guidance Counselor and the Reading Curriculum.

    Science.gov (United States)

    Ediger, Marlow

    There are many ways guidance counselors can help teachers achieve more optimal reading instruction. Counselors first may have to ascertain the kinds of problems faced by a student in learning to read. Assessing a student's ability to use picture clues to decipher words may be necessary with primary grade students. Knowledge about phonics, using…

  9. Research Requirements for Future Visual Guidance Systems

    Science.gov (United States)

    1994-02-01

    20591. 5. FAA Advisory Circular 150/5340-18, Standards for Airport Sign Systems, latest edition, Washington, DC 20591. 6. Bonaventura , Vincent...Dunlap and Associates, March 1952, New York. 8. Bonaventura , Vincent E., A Proposed Method of Color Coding Airport Taxi Guidance-Sins, The Port of New

  10. Museum Personnel's Opinions on Mobile Guidance Systems

    Science.gov (United States)

    Yoshimura, Hirokazu; Sekiguchi, Hiromi; Yabumoto, Yoshitaka

    2007-01-01

    While opinions from the general public are certainly important, opinions from the museum staff are also necessary to improve user service systems. this article introduces two groups of museum staff who have evaluated the usability of mobile guidance systems in Japanese museums. One group is the research team who used the PDA system in the National…

  11. 33 CFR 385.5 - Guidance memoranda.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Guidance memoranda. 385.5 Section 385.5 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE PROGRAMMATIC REGULATIONS FOR THE COMPREHENSIVE EVERGLADES RESTORATION PLAN General...

  12. Epilepsy in the Classroom: Guidance for Educators.

    Science.gov (United States)

    Lassner, Lee M.

    This paper for educators, school psychologists, and counselors attempts to provide guidance for meeting the needs of students with epilepsy. Stressed throughout the paper are ways to provide for the child's special needs while fostering his/her self esteem and full participation in classroom activities. The paper addresses the following topics:…

  13. Designing Schoolwide Programs. Non-Regulatory Guidance

    Science.gov (United States)

    US Department of Education, 2006

    2006-01-01

    This guidance offers a renewed vision for the use of the schoolwide program, both as a reform strategy and as a means of realizing the high standards for student achievement envisioned by the No Child Left Behind Act of 2001 (NCLB). It is intended to be used as a companion document to the statute and regulations, as well as a technical assistance…

  14. "Telling Tales": Using Narrative in Career Guidance

    Science.gov (United States)

    Reid, Hazel; West, Linden

    2011-01-01

    In this article the authors argue for the importance of narrative-based approaches in career guidance work in an uncertain, unpredictable world. This requires a paradigmatic shift in thinking that can be too difficult, at present, for some practitioners. The article reports on the first phase of a collaborative project with a group of…

  15. A Leading Role for Career Guidance Counselors

    Science.gov (United States)

    Reese, Susan

    2010-01-01

    Without structured guidance activities, students may drift through high school without learning about all of the career opportunities available and without gaining the skills that can help them take advantage of those opportunities. They may also be in danger of failing to continue on to postsecondary education, or even worse, of dropping out of…

  16. Effective Child Guidance: An Educator's Guidebook.

    Science.gov (United States)

    Hill, Brent Mathews

    This guidebook is designed to assist educators in becoming more effective child guidance leaders within the school system. Sections discuss the following areas: (1) indicators of current emotional problems; (2) children's common emotional problems, including fears, separation and loss, misbehavior motivations, aggressiveness, stealing, lying,…

  17. Athletics Guidance Aims for Level Field

    Science.gov (United States)

    Samuels, Christina A.

    2013-01-01

    A document from the U.S. Department of Education intended to clarify schools' responsibility to make sure students with disabilities have access to extracurricular sports has drawn sharply different opinions. Disability-rights advocates welcome the guidance, while critics say federal officials are pushing requirements that could place new…

  18. Angiogenesis related gene expression profiles of EA.hy926 cells induced by irbesartan: a possible novel therapeutic approach

    Institute of Scientific and Technical Information of China (English)

    MA Cong; LU Xue-chun; LUO Yun; CAO Jian; YANG Bo; GAO Yan; LIU Xian-feng; FAN Li

    2012-01-01

    Background Angiogenesis occurs commonly in various physiological and pathological processes.Improving blood supply through promoting angiogenesis is a novel approach for treating ischemic diseases.Angiotensin Ⅱ type 1 receptor blockers (ARBs) dominate the management of hypertension,but evidence of their role in angiogenesis is contradictory.Here we explored the angiogenic effects of ARBs through characterizing gene expression of the human umbilical vein endothelial cell line EA.hy926 exposed to irbesartan.Methods The human umbilical vein endothelial cell line EA.hy926 was grown for 72 hours after treatment with different concentrations of irbesartan.The cell proliferative capacity was assessed by CCK8 assay at 24,48 and 72 hours.Gene expression levels in EA.hy926 cells responding to irbesartan were measured under optimal proliferation conditions by microarray analysis using Affymetrix U133 plus 2.0.The differential expression of genes involved in angiogenesis was identified through cluster analysis of the resulting microarray data.Quantitative RT-PCR and Western blotting analyses were used to validate differential gene expression related to the angiogenesis process.Results In the 10-4,10-5,10-6 mol/L treatment groups,cell proliferation studies revealed significantly increased proliferation in EA.hy926 cells after 24 hours of irbesartan treatment.However,after 48 and 72 hours of treatment with different concentrations of irbesartan,there was no significant difference in cell proliferation observed in any treatment group.We selected the group stimulated with irbersartan at a concentration of 10-6 mol/L for microarray experiments.Statistical analysis of the microarray data resulted in the identification of 56 gene transcripts whose expression patterns were significantly correlated,negatively or positively,with irbesartan treatment.Cluster analysis showed that these genes were involved in angiogenesis,extracellular stimulus,binding reactions and skeletal system

  19. Application of Bayesian Neural Networks to Energy Reconstruction in EAS Experiments for ground-based TeV Astrophysics

    CERN Document Server

    Bai, Ying; Lan, JieQin; Gao, WeiWei

    2016-01-01

    A toy detector array has been designed to simulate the detection of cosmic rays in Extended Air Shower(EAS) Experiments for ground-based TeV Astrophysics. The primary energies of protons from the Monte-Carlo simulation have been reconstructed by the algorithm of Bayesian neural networks (BNNs) and a standard method like the LHAASO experiment\\cite{lhaaso-ma}, respectively. The result of the energy reconstruction using BNNs has been compared with the one using the standard method. Compared to the standard method, the energy resolutions are significantly improved using BNNs. And the improvement is more obvious for the high energy protons than the low energy ones.

  20. Accelerating growth of HFC-227ea (1,1,1,2,3,3,3-heptafluoropropane) in the atmosphere

    DEFF Research Database (Denmark)

    Laube, J.C.; Martinerie, P.; Witrant, E.

    2010-01-01

    We report the first measurements of 1,1,1,2,3,3,3-heptafluoropropane (HFC-227ea), a substitute for ozone depleting compounds, in air samples originating from remote regions of the atmosphere and present evidence for its accelerating growth. Observed mixing ratios ranged from below 0.01 ppt in deep...... firn air to 0.59 ppt in the current northern mid-latitudinal upper troposphere. Firn air samples collected in Greenland were used to reconstruct a history of atmospheric abundance. Year-on-year increases were deduced, with acceleration in the growth rate from 0.029 ppt per year in 2000 to 0.056 ppt per...

  1. Low modulation bias InGaN-based integrated EA-modulator-laser on semipolar GaN substrate

    KAUST Repository

    Shen, Chao

    2015-10-04

    In summary, we demonstrated the monolithic integration of electroabsorption modulator with laser diode and measured DC and AC modulation characteristics of the device, which is grown on (2021̅) plane GaN substrate. By alternating the modulation voltage at −3.5 V and 0 V, we achieve the laser output power of < 1.5 mW to > 9 mW, respectively, leading to ∼8.1 dB On/Off ratio. Our results clearly show that a low power consumption modulator can be achieved with semipolar EA-modulator compared to that of the c-plane devices.

  2. Crafting Final Impressions: When It's Time to Say Good-Bye.

    Science.gov (United States)

    Alexander, Nancy P.

    1997-01-01

    Presents guidance for child care administrators when customers, parents, children, or employees depart. Argues that a positive final impression is achieved by providing closure, maintaining service levels, and creating a plan for withdrawal. Provides guidance for helping children say good-bye, obtaining referrals from former customers, and…

  3. Behavioral. Physiological, and Biochemical Characterization of EA6033 in African Green Monkeys

    Science.gov (United States)

    2017-03-01

    Suite 1204, Arlington, VA 22202-4302. Respondents should be aware that notwithstanding any other provision of law , no person shall be subject to... euthanasia was performed at the end of the evaluation period to minimize potential animal suffering while also providing supplementary information...exposure days with the exception of euthanasia following the final behavioral testing component. Blood Collection and Processing Approximately

  4. The cosmic ray proton, helium and CNO fluxes in the 100 TeV energy region from TeV muons and EAS atmospheric Cherenkov light observations of MACRO and EAS-TOP

    CERN Document Server

    Aglietta, M; Ambrosio, M; Antolini, R; Antonioli, P; Arneodo, F; Baldini, A; Barbarino, G C; Barish, B C; Battistoni, G; Becherini, Y; Bellotti, R; Bemporad, C; Bergamasco, L; Bernardini, P; Bertaina, M; Bilokon, H; Bower, C; Brigida, M; Bussino, S; Cafagna, F; Calicchio, M; Campana, D; Carboni, M; Caruso, R; Castagnoli, C; Castellina, A; Cecchini, S; Cei, F; Chiarella, V; Chiarusi, T; Chiavassa, A; Choudhary, B C; Cini, G; Coutu, S; Cozzi, M; De Cataldo, G; De Marzo, C; De Mitri, I; De Vincenzi, M; Dekhissi, H; Derkaoui, J; Di Credico, A; Di Sciascio, G; Erriquez, O; Favuzzi, C; Forti, C; Fulgione, W; Fusco, P; Galeotti, P; Ghia, P L; Giacomelli, G; Giannini, G; Giglietto, N; Giorgini, M; Grassi, M; Grillo, A; Guarino, F; Gustavino, C; Habig, A; Hanson, K; Heinz, R; Iacovacci, M; Iarocci, E; Katsavounidis, E; Katsavounidis, I; Kearns, E; Kim, H; Kyriazopoulou, S; Lamanna, E; Lane, C; Levin, D S; Lipari, P; Longley, N P; Longo, M J; Loparco, F; Maaroufi, F; Mancarella, G; Mandrioli, G; Mannocchi, G; Margiotta, A; Marini, A; Martello, D; Marzari-Chiesa, A; Mazziotta, M N; Michael, D G; Monacelli, P; Montaruli, T; Monteno, M; Morello, C; Mufson, S; Musser, J; Navarra, G; Nicolò, D; Nolty, R; Orth, C; Osteria, G; Palamara, O; Patera, V; Patrizii, L; Pazzi, R; Peck, C W; Perrone, L; Petrera, S; D'Ettorre-Piazzoli, B; Popa, V; Rainó, A; Reynoldson, J; Ronga, F; Saavedra, O; Satriano, C; Scapparone, E; Scholberg, K; Sciubba, A; Sioli, M; Sirri, G; Sitta, M; Spinelli, P; Spinetti, M; Spurio, M; Stamerra, A; Steinberg, R; Stone, J L; Sulak, L R; Surdo, A; Tarle, G; Togo, V; Trinchero, G C; Vakili, M; Valchierotti, S; Vallania, P; Vernetto, S; Vigorito, C; Walter, C W; Webb, R; 10.1016/j.astropartphys.2004.01.005

    2004-01-01

    The primary cosmic ray (CR) proton, helium and CNO fluxes in the energy range 80-300 TeV are studied at the National Gran Sasso Laboratories by means of EAS-TOP (Campo Imperatore, 2005 m a.s.l.) and MACRO (deep underground, 3100 m w.e., the surface energy threshold for a muon reaching the detector being E/sub mu //sup th/ approximately=1.3 TeV). The measurement is based on: (a) the selection of primaries based on their energy/nucleon (i.e., with energy/nucleon sufficient to produce a muon with energy larger than 1.3 TeV) and the reconstruction of the shower geometry by means of the muons recorded by MACRO in the deep underground laboratories; (b) the detection of the associated atmospheric Cherenkov light (C.l.) signals by means of the C.l. detector of EAS-TOP. The C.l. density at core distance r>100 m is directly related to the total primary energy E/sub 0/. Proton and helium ("p+He") and proton, helium and CNO ("p +He+CNO") primaries are thus selected at E/sub 0/ approximately=80 Te V, and at E/sub 0/ appro...

  5. Nematicidal activity of Cry1Ea11 from Bacillus thuringiensis BRC-XQ12 against the pine wood nematode (Bursaphelenchus xylophilus).

    Science.gov (United States)

    Huang, Tianpei; Lin, Qunxin; Qian, Xiaoli; Zheng, Ying; Yao, Junmin; Wu, Huachuan; Li, Mengmeng; Jin, Xin; Pan, Xiaohong; Zhang, Lingling; Guan, Xiong

    2017-09-12

    The nematicidal activity of 92 Bacillus thuringiensis (Bt) strains against the pine wood nematode Bursaphelenchus xylophilus, one of the world's top 10 plant-parasitic nematodes, was determined. The insecticidal crystal proteins (ICPs) from Bt BRC-XQ12 were the most toxic to B. xylophilus with an LC50 of 32.13 μg/mL. Since the ICPs expressed by Bt BRC-XQ12 were closest to Cry1Ea6 and Bt BRC-XQ12 contained four kinds of cry1 subgenes (cry1Aa, cry1Cb, cry1Ea and cry1Ia), Cry1Ea was most likely to be the key active component against the nematode. The 3516 bp cry1Ea11 gene from Bt BRC-XQ12, as designated by the Bt delta-endotoxin nomenclature committee, was expressed in Escherichia coli. Purified Cry1Ea11 showed an LC50 of 32.53 μg/mL and 23.23 μg/mL at 24 h and 48 h with corresponding virulence equations of Y=32.15X + 1.38 (R(2)=0.9951) and Y=34.29X + 3.16 (R(2)=0.9792), respectively. In order to detect the pathway of Bt Cry1Ea11 entering into B. xylophilus, the nematode was fed with NHS-rhodamine-labeled GST-Cry1Ea11. The results of confocal laser scanning microscopy (CLSM) showed that the 159 kDa GST-Cry1Ea11 could be detected in the stylet and the esophageal lumen of the pine wood nematode, indicating that GST-Cry1Ea11 could enter into the nematode through the stylet. As far as we know, no Cry1 proteins have activity against plant-parasitic nematodes before. These results demonstrate that Cry1Ea11 is a promising nematicidal protein for controlling pine wilt disease (PWD) rendered by B. xylophilus, further dramatically broadening the spectrum of Bt ICPs.

  6. 76 FR 12373 - Notice of Availability of Final Supplement to the Environmental Assessment for the Proposed Pa...

    Science.gov (United States)

    2011-03-07

    ... Hawaii, LLC Irradiator in Honolulu, HI AGENCY: Nuclear Regulatory Commission. ACTION: Notice of... Final Supplement to the Environmental Assessment (EA) for the irradiator proposed by Pa'ina Hawaii, LLC... from earthquakes, tsunamis, and hurricanes at the alternative locations will be small....

  7. 75 FR 5757 - Notice of Availability of Final Environmental Assessment and Finding of No Significant Impact for...

    Science.gov (United States)

    2010-02-04

    ... concentrations of organic matter and some woody debris. Using the berm material has numerous benefits as a planting medium. The high concentration of organic matter provides both soil fertility and moisture...: Copies of the Final EA and FONSI, or additional information on matters related to the project, can be...

  8. 78 FR 36743 - Adoption of Final Environmental Assessment (UT-040-09-03) Prepared for the Upper Kanab Creek...

    Science.gov (United States)

    2013-06-19

    ... Natural Resources Conservation Service Adoption of Final Environmental Assessment (UT-040-09-03) Prepared... Lake City, Utah 84138; email at gary.mcrae@ut.usda.gov . SUPPLEMENTARY INFORMATION: NRCS announces its intent to adopt the Kanab Creek Watershed Vegetation Management Project EA (UT-040-09-03) prepared by...

  9. A Formal Investigation of the Organization of Guidance Behavior: Implications for Humans and Autonomous Guidance

    Science.gov (United States)

    Kong, Zhaodan

    Guidance behavior generated either by artificial agents or humans has been actively studied in the fields of both robotics and cognitive science. The goals of these two fields are different. The former is the automatic generation of appropriate or even optimal behavior, while the latter is the understanding of the underlying mechanism. Their challenges, though, are closely related, the most important one being the lack of a unified, formal and grounded framework where the guidance behavior can be modeled and studied. This dissertation presents such a framework. In this framework, guidance behavior is analyzed as the closed-loop dynamics of the whole agent-environment system. The resulting dynamics give rise to interaction patterns. The central points of this dissertation are that: first of all, these patterns, which can be explained in terms of symmetries that are inherent to the guidance behavior, provide building blocks for the organization of behavior; second, the existence of these patterns and humans' organization of their guidance behavior based on these patterns are the reasons that humans can generate successful behavior in spite of all the complexities involved in the planning and control. This dissertation first gives an overview of the challenges existing in both scientific endeavors, such as human and animal spatial behavior study, and engineering endeavors, such as autonomous guidance system design. It then lays out the foundation for our formal framework, which states that guidance behavior should be interpreted as the collection of the closed-loop dynamics resulting from the agent's interaction with the environment. The following, illustrated by examples of three different UAVs, shows that the study of the closed-loop dynamics should not be done without the consideration of vehicle dynamics, as is the common practice in some of the studies in both autonomous guidance and human behavior analysis. The framework, the core concepts of which are

  10. Downstream of guidance receptors: entering the baroque period of axon guidance signaling.

    Science.gov (United States)

    Schmucker, Dietmar

    2003-09-25

    The Roundabout ("Robo") family of transmembrane proteins are the receptors and mediators of the repellent axon guidance signal Slit. However, the molecular mechanisms by which Robo signaling leads to growth cone or neuron repulsion are still poorly understood. A study by Fan et al. in this issue of Neuron expands the repertoire of Robo pathway components and stimulates a new look at axon guidance signaling in general.

  11. 78 FR 4848 - Social Media: Consumer Compliance Risk Management Guidance

    Science.gov (United States)

    2013-01-23

    ... more interactive. Financial institutions may use social media in a variety of ways, including marketing... INSTITUTIONS EXAMINATION COUNCIL Social Media: Consumer Compliance Risk Management Guidance AGENCY: Federal... this proposed guidance entitled ``Social Media: Consumer Compliance Risk Management...

  12. 75 FR 48973 - Draft Guidance for Industry: Prevention of Salmonella

    Science.gov (United States)

    2010-08-12

    ... HUMAN SERVICES Food and Drug Administration Draft Guidance for Industry: Prevention of Salmonella... availability of a draft guidance entitled ``Prevention of Salmonella Enteritidis in Shell Eggs During... ``Prevention of Salmonella Enteritidis in Shell Eggs During Production, Storage, and Transportation''...

  13. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Webb, Robert C. [Texas A& M University; Kamon, Teruki [Texas A& M University; Toback, David [Texas A& M University; Safonov, Alexei [Texas A& M University; Dutta, Bhaskar [Texas A& M University; Dimitri, Nanopoulos [Texas A& M University; Pope, Christopher [Texas A& M University; White, James [Texas A& M University

    2013-11-18

    Overview The High Energy Physics Group at Texas A&M University is submitting this final report for our grant number DE-FG02-95ER40917. This grant has supported our wide range of research activities for over a decade. The reports contained here summarize the latest work done by our research team. Task A (Collider Physics Program): CMS & CDF Profs. T. Kamon, A. Safonov, and D. Toback co-lead the Texas A&M (TAMU) collider program focusing on CDF and CMS experiments. Task D: Particle Physics Theory Our particle physics theory task is the combined effort of Profs. B. Dutta, D. Nanopoulos, and C. Pope. Task E (Underground Physics): LUX & NEXT Profs. R. Webb and J. White(deceased) lead the Xenon-based underground research program consisting of two main thrusts: the first, participation in the LUX two-phase xenon dark matter search experiment and the second, detector R&D primarily aimed at developing future detectors for underground physics (e.g. NEXT and LZ).

  14. Improvement of solvent production from xylose mother liquor by engineering the xylose metabolic pathway in Clostridium acetobutylicum EA 2018.

    Science.gov (United States)

    Li, Zhilin; Xiao, Han; Jiang, Weihong; Jiang, Yu; Yang, Sheng

    2013-10-01

    Xylose mother liquor (XML) is a by-product of xylose production through acid hydrolysis from corncobs, which can be used potentially for alternative fermentation feedstock. Sixteen Clostridia including 13 wild-type, 1 industrial strain, and 2 genetically engineered strains were screened in XML, among which the industrial strain Clostridium acetobutylicum EA 2018 showed the highest titer of solvents (12.7 g/L) among non-genetic populations, whereas only 40% of the xylose was consumed. An engineered strain (2018glcG-TBA) obtained by combination of glcG disruption and expression of the D-xylose proton-symporter, D-xylose isomerase, and xylulokinase was able to completely utilize glucose and L-arabinose, and 88% xylose in XML. The 2018glcG-TBA produced total solvents up to 21 g/L with a 50% enhancement of total solvent yield (0.33 g/g sugar) compared to that of EA 2018 (0.21 g/g sugar) in XML. This XML-based acetone-butanol-ethanol fermentation using recombinant 2018glcG-TBA was estimated to be economically promising for future production of solvents.

  15. Solar Wind Electron Strahl - Preparations for Measurement with Solar Orbiter's SWA/EAS Sensor after Lessons from Helios and Cluster.

    Science.gov (United States)

    Owen, C. J.

    2014-12-01

    The nature of the electron strahl population in the solar wind is a key diagnostic of the connectivity of the magnetic field to the solar atmosphere. As such, its measurement is fundamental to the success of the Solar Orbiter mission, with its scientific goals largely focussed around making the link between physical processes observed remotely in the near-Sun environment and the fields and particle populations detected in situ at the spacecraft. The Electron Analyser System (EAS) is part of the Solar Wind Analysers (SWA) suite of sensors which will be flown on the mission. It will make measurements of the 3D velocity distribution of electrons in the energy range of a few eV up to ~5 keV. In this presentation we first briefly review the expected capabilities of EAS. We then describe the strategies being developed to accurately categorize the electron strahl population with the sensor, with particular reference to our ongoing studies of relevant existing datasets from the Helios and Cluster missions.

  16. Spatially Resolved Spectroscopic Observations of a Possible E+A Progenitor SDSS J160241.00+521426.9

    CERN Document Server

    Matsubayashi, Kazuya; Goto, Tomotsugu; Akita, Akira; Sugai, Hajime; Kawai, Atsushi; Shimono, Atsushi; Hattori, Takashi

    2011-01-01

    In order to investigate the evolution of E+A galaxies, we observed a galaxy SDSS J160241.00+521426.9, a possible E+A progenitor which shows both emission and strong Balmer absorptions, and its neighbor galaxy. We used the integral field spectroscopic mode of the Kyoto Tridimensional Spectrograph (Kyoto3DII), mounted on the University of Hawaii 88-inch telescope located on Mauna Kea, and the slit-spectroscopic mode of the Faint Object Camera and Spectrograph (FOCAS) on the Subaru Telescope. We found a strong Balmer absorption region in the center of the galaxy and an emission-line region located 2 kpc from the center, in the direction of its neighbor galaxy. The recession velocities of the galaxy and its neighbor galaxy differ only by 100 km s^-1, which suggests that they are a physical pair and would have been interacting. Comparing observed Lick indices of Balmer lines and color indices with those predicted from stellar population synthesis models, we find that a suddenly quenched star-formation scenario is ...

  17. School Guidance and Discipline: teachers’ and students’ construction of classroom knowledge in two Hong Kong secondary schools

    Directory of Open Access Journals (Sweden)

    Ming-Tak Hue

    2006-04-01

    Full Text Available Most Hong Kong secondary schools have two teams of guidance and discipline teachers to manage students’ misbehaviour. The guidance team is mainly responsible for providing a personal counselling service and for carrying out guidance programmes, such as sex education. The discipline team works with students who have been identified as having behavioural problems. They are also responsible for enforcing discipline policy, such as the wearing of school uniform. Most teachers and school managers are concerned with the difficulty of integrating guidance and discipline into schooling. Many studies have shown that guidance teachers are described as ‘soft’ whereas discipline teachers as described as ‘strict’ and ‘tough’. Each team of teachers has a contrasting rationale as to how best to help students resolve their difficulties. However, no research has yet been completed into how guidance and discipline are implemented in the classroom. This article focuses on this area and reports a study of what classroom knowledge teachers and students construct, with respect to the relationship between guidance and discipline. The qualitative methods for data collection are described and two case studies are presented. The analysis shows that such a relationship differs from school to school, and that teachers’ construct of classroom knowledge of guidance and discipline is closely linked to the features of school organisation of the schools to which these teachers belong. Finally, the paper looks at the implication of this study in drawing school managers’ and policy makers’ attention to the impact of school organisation on guidance and discipline in the classroom.

  18. [Auditory guidance systems for the visually impaired people].

    Science.gov (United States)

    He, Jing; Nie, Min; Luo, Lan; Tong, Shanbao; Niu, Jinhai; Zhu, Yisheng

    2010-04-01

    Visually impaired people face many inconveniences because of the loss of vision. Therefore, scientists are trying to design various guidance systems for improving the lives of the blind. Based on sensory substitution, auditory guidance has become an interesting topic in the field of biomedical engineering. In this paper, we made a state-of-technique review of the auditory guidance system. Although there have been many technical challenges, the auditory guidance system would be a useful alternative for the visually impaired people.

  19. Effect of Autopilot Structure on Proportional Navigation Guidance

    Institute of Scientific and Technical Information of China (English)

    XIA Qun-li; LIU Yi-ying; QI Zai-kang

    2007-01-01

    The dynamic characteristics of acceleration autopilot and attitude autopilot are discussed in detail.Also, a comparison study was made between these two different types of control schemes for guidance loop.By means of simulation, it is concluded that the guidance accuracy is mainly determined by the slowest subsystem among different system dynamics.For air-to-ground missiles, with limited terminal guidance time, the control scheme of acceleration autopilot combined with proportional navigation guidance (PNG) law is the better choice.

  20. 10 CFR 430.4 - Sources for information and guidance.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Sources for information and guidance. 430.4 Section 430.4... Provisions § 430.4 Sources for information and guidance. (a) General. The standards listed in this paragraph... reference. These sources are given here for information and guidance. (b) IESNA. Illuminating Engineering...

  1. Acid rain compliance: The need for regulatory guidance

    Energy Technology Data Exchange (ETDEWEB)

    Solomon, B.D. [Environmental Protection Agency, Washington, DC (United States)

    1993-07-01

    This article presents a broad view of the need for regulatory guidance when confronting the problem of acid rain. The two major topics addressed are (1) Why is guidance needed and (2) What kind of guidance is needed. Discussion of rate and accounting treatment of allowances, acid rain compliance planning, and allowance trading and energy efficiency are included.

  2. 76 FR 75771 - Emergency Planning Guidance for Nuclear Power Plants

    Science.gov (United States)

    2011-12-05

    ... Part 52 RIN 3150-AI10 Emergency Planning Guidance for Nuclear Power Plants AGENCY: Nuclear Regulatory... Regulatory Commission (NRC) is issuing Supplement 3, ``Guidance for Protective Action Strategies,'' to NUREG... Guidance Emergency Planning for Nuclear Power Plants;'' and NUREG/CR-7002, ``Criteria for Development of...

  3. Managing Student Behavior during Large Group Guidance: What Works Best?

    Science.gov (United States)

    Quarto, Christopher J.

    2007-01-01

    Participants provided information pertaining to managing non-task-related behavior of students during large group guidance lessons. In particular, school counselors were asked often how often they provide large group guidance, the frequency of which students exhibit off-task and/or disruptive behavior during guidance lessons, and techniques they…

  4. Tobaccofree Sports Stadia: European Policies and Guidance

    Directory of Open Access Journals (Sweden)

    Matthew Philpott

    2016-03-01

    Full Text Available Over 20 million people – including many children and young people - attend professional football matches across Europe each week, with many more attending other professional and amateur sports fixtures. The vast majority of European sports venues take place in semi-enclosed structures with roofed stands, and yet there are still very low levels of smokefree and tobaccofree policies in operation. Building on research findings that only 10 out of UEFA’s 54 European countries have football stadia that operate tobaccofree policies, Healthy Stadia has worked with UEFA and World Heart Federation to develop new guidance materials for clubs, multi-purpose stadium operators and governing bodies of sport to assist in the development and enforcement of strong tobacco control policies. This presentation will give a benchmark of current policies in place, support offered through the new guidance materials, and advice on how sports organisations can go beyond national tobacco control legislation to implement tobaccofree policies.

  5. ROUTE PLAN DESIGNER FOR TRACTOR GUIDANCE SYSTEMS

    DEFF Research Database (Denmark)

    Sveistrup, Daniel; Jørgensen, Rasmus Nyholm; Green, Ole

    2010-01-01

    Earlier works have shown field trial designs to be very labor extensive, even when combining autoguidancesystems with conventional machinery.Designing routes for semi-automated systems in a controlled manner is both resource demandingand complicated. Different types of auto-guidance systems vary....... The software works in conjunction with Google Earth to import field boundaries,and for viewing, validating and georeferencing completed field trial designs. The software isplatform independent and online distributed by means of the Java development environment.Two case studies were applied for demonstrating...... was outlined, it took less thanone hour entering the design into the software and generating the auto-guidance files.KeywordsGIS, Auto steering systems, plot trial design, full-scale field trials, Java...

  6. Practical guidance on undertaking a service evaluation.

    Science.gov (United States)

    Moule, Pam; Armoogum, Julie; Dodd, Emily; Donskoy, Anne-Laure; Douglass, Emma; Taylor, Julie; Turton, Pat

    2016-07-06

    This article describes the basic principles of evaluation, focusing on the evaluation of healthcare services. It emphasises the importance of evaluation in the current healthcare environment and the requirement for nurses to understand the essential principles of evaluation. Evaluation is defined in contrast to audit and research, and the main theoretical approaches to evaluation are outlined, providing insights into the different types of evaluation that may be undertaken. The essential features of preparing for an evaluation are considered, and guidance provided on working ethically in the NHS. It is important to involve patients and the public in evaluation activity, offering essential guidance and principles of best practice. The authors discuss the main challenges of undertaking evaluations and offer recommendations to address these, drawing on their experience as evaluators.

  7. [Problems of reception in a guidance center].

    Science.gov (United States)

    Mattelaer, P

    1975-01-01

    The aim of this communication is not to criticise the work of guidance, but to analyse its efficiency and validity in order to formulate concrete proposals. One can distinguish three periods in the evolution of the work in a guidance center. In the first period, it is a methodological concern which presided to this type of work. In the second period, one thought that there was to many preliminary investigations and it was decided to take the child in treatment more rapidly. During the third period, the attention has primarily be centered on the child's problems. The author suggests some solutions. He considers it is necessary to abandon the multidisciplinary approach. He advises to always consider one case at the time within a therapeutic and diagnostic frame. Therapy has to be conducted by one person, even if this person has to treat the whole family.

  8. GUIDANCE DOCUMENT ON IMPLEMENTATION OF THE ...

    Science.gov (United States)

    The Agreement in Principle for the Stage 2 M-DBP Federal Advisory Committee contains a list of treatment processes and management practices for water systems to use in meeting additional Cryptosporidium treatment requirements under the LT2ESWTR. This list, termed the microbial toolbox, includes watershed control programs, alternative intake locations, pretreatment processes, additional filtration barriers, inactivation technologies, and enhanced plant performance. The intent of the microbial toolbox is to provide water systems with broad flexibility in selecting cost-effective LT2ESWTR compliance strategies. Moreover, the toolbox allows systems that currently provide additional pathogen barriers or that can demonstrate enhanced performance to receive additional Cryptosporidium treatment credit. Provide guidance to utilities with surface water supplies and to state drinking water programs on the use of different treatment technologies to reduce the level of Cryptosporidium in drinking water. Technologies included in the guidance manual may be used to achieve compliance with the requirements of the LT2ESWTR.

  9. Taxonometric guidance for developing quality assurance.

    Science.gov (United States)

    Thomadsen, Bruce; Lin, She-Woei

    2008-01-01

    A taxonomy is an ordered classification system. In error reduction analysis, an examination of the human failures that lead to an event often uses a taxonomy to classify the failures according to some aspect of their characteristics. These classifications provide insights into the forces that kept the persons involved from achieving their intended actions. They also can provide guidance for changing the situation to prevent failure in the future. For example, the corrective action would be different if a therapist pressed the wrong button because several buttons looked alike or they forgot which button to press. Different types of failures lead to particular types of remediation. Taxonomies can provide guidance in selecting between possible corrective actions.

  10. 76 FR 43690 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Science.gov (United States)

    2011-07-21

    ... HUMAN SERVICES Food and Drug Administration (Formerly 2007D-0309) Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document: Electrocardiograph Electrodes; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY: The Food and...

  11. 75 FR 54637 - Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance...

    Science.gov (United States)

    2010-09-08

    ... HUMAN SERVICES Food and Drug Administration Guidance for Industry and Food and Drug Administration Staff; Class II Special Controls Guidance Document for Certain Percutaneous Transluminal Coronary Angioplasty (PTCA) Catheters; Availability AGENCY: Food and Drug Administration, HHS. ACTION: Notice. SUMMARY:...

  12. Orbital maneuvering vehicle guidance, navigation and control

    Science.gov (United States)

    Huber, W. G.; Finnell, W., III

    1985-01-01

    This paper describes the Orbital Maneuvering Vehicle (OMV) concept and its intended role. It recaps the past activities leading up to the current concept and summarizes the present status and plans. The various types of missions and operating modes required by the OMV are described as the basis of the guidance, navigation and control (GN&C) requirements. The general GN&C problem is outlined with potential hardware solutions.

  13. Dynamic Route Guidance Using Improved Genetic Algorithms

    Directory of Open Access Journals (Sweden)

    Zhanke Yu

    2013-01-01

    Full Text Available This paper presents an improved genetic algorithm (IGA for dynamic route guidance algorithm. The proposed IGA design a vicinity crossover technique and a greedy backward mutation technique to increase the population diversity and strengthen local search ability. The steady-state reproduction is introduced to protect the optimized genetic individuals. Furthermore the junction delay is introduced to the fitness function. The simulation results show the effectiveness of the proposed algorithm.

  14. Puncture of thoracic lesions under sonographic guidance.

    OpenAIRE

    Afschrift, M; Nachtegaele, P; Voet, D; Noens, L.; Van Hove, W; Van der Straeten, M; Verdonk, G

    1982-01-01

    Thirty-six punctures of thoracic lesions have been performed with a compound B-scanner or a real-time linear-array scanner for guidance. Twenty-three fluid collections were punctured and aspiration biopsies were performed on 13 echogenic lesions. All the punctures were successful at the first attempt. No complications occurred. The results confirm the usefulness of sonography for guiding punctures of thoracic fluid effusions and solid masses. Usually a static B-scanner is sufficient, but when...

  15. Human Genetic Disorders of Axon Guidance

    OpenAIRE

    Engle, Elizabeth C

    2010-01-01

    This article reviews symptoms and signs of aberrant axon connectivity in humans, and summarizes major human genetic disorders that result, or have been proposed to result, from defective axon guidance. These include corpus callosum agenesis, L1 syndrome, Joubert syndrome and related disorders, horizontal gaze palsy with progressive scoliosis, Kallmann syndrome, albinism, congenital fibrosis of the extraocular muscles type 1, Duane retraction syndrome, and pontine tegmental cap dysplasia. Gene...

  16. Education, consultation, guidance, students, advisor, teacher

    Directory of Open Access Journals (Sweden)

    M Seyedmajidi

    2013-09-01

    Full Text Available Introduction: Student counseling and supervision play an important role to overcome learning problems and to achieve educational goals. The present study is intended to investigate viewpoints of students regarding educational guidance and advice studying at Babol University of Medical Sciences. Methods: In this descriptive cross-sectional survey, viewpoints of 480 students were collected by a questionnaire. The validity and reliability of the questionnaire had been approved before. Data were analyzed using SPSS version 17 software. Chi- square and ANOVA tests were administered. Results: 61.2% of all participants were female and 38.8% were males with mean age of 21.3±4.0. 37.2% of these students lacked sufficient knowledge and information on how to request from their advisors for help and guidance. Half of students (50.3% reported attendance of advisors and holding routine consultation is inappropriate. Advisors made more educational files for females compare to males (P=0.001. No difference observed regarding educational disciplines of the advisors regarding students were dissatisfied with help and guidance received from paramedics and dentistry students in most fields (87.3% and 81.5% respectively. Conclusion: It seems that either student has no sufficient information about tasks of advisors and/or advisors may not do their tasks properly. It is recommended the students to be acquainted with advisors’ tasks upon their entrance into the university. Training classes for new academics would be helpful.

  17. Blind guidance system based on laser triangulation

    Science.gov (United States)

    Wu, Jih-Huah; Wang, Jinner-Der; Fang, Wei; Lee, Yun-Parn; Shan, Yi-Chia; Kao, Hai-Ko; Ma, Shih-Hsin; Jiang, Joe-Air

    2012-05-01

    We propose a new guidance system for the blind. An optical triangulation method is used in the system. The main components of the proposed system comprise of a notebook computer, a camera, and two laser modules. The track image of the light beam on the ground or on the object is captured by the camera and then the image is sent to the notebook computer for further processing and analysis. Using a developed signal-processing algorithm, our system can determine the object width and the distance between the object and the blind person through the calculation of the light line positions on the image. A series of feasibility tests of the developed blind guidance system were conducted. The experimental results show that the distance between the test object and the blind can be measured with a standard deviation of less than 8.5% within the range of 40 and 130 cm, while the test object width can be measured with a standard deviation of less than 4.5% within the range of 40 and 130 cm. The application potential of the designed system to the blind guidance can be expected.

  18. EPA guidance on cultural competence training.

    Science.gov (United States)

    Schouler-Ocak, Meryam; Graef-Calliess, Iris T; Tarricone, Ilaria; Qureshi, Adil; Kastrup, Marianne C; Bhugra, Dinesh

    2015-03-01

    The stress of migration as well as social factors and changes related to the receiving society may lead to the manifestation of psychiatric disorders in vulnerable individuals after migration. The diversity of cultures, ethnicities, races and reasons for migration poses a challenge for those seeking to understand how illness is experienced by immigrants whose backgrounds differ significantly from their clinicians. Cultural competence represents good clinical practice and can be defined as such that a clinician regards each patient in the context of the patient's own culture as well as from the perspective of the clinician's cultural values and prejudices. The EPA Guidance on cultural competence training outlines some of the key issues related to cultural competence and how to deal with these. It points out that cultural competence represents a comprehensive response to the mental health care needs of immigrant patients and requires knowledge, skills and attitudes which can improve the effectiveness of psychiatric treatment. To reach these aims, both individual and organizational competence are needed, as well as teaching competence in terms of educational leadership. The WPA Guidance on Mental Health and Mental Health Care for Migrants and the EPA Guidance on Mental Health Care for Migrants list a series of recommendations for policy makers, service providers and clinicians; these are aimed at improving mental health care for immigrants. The authors of this paper would like to underline these recommendations and, focusing on cultural competency and training, believe that they will be of positive value. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  19. NRC ARDC Guidance Support Status Report

    Energy Technology Data Exchange (ETDEWEB)

    Holbrook, Mark R. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-07-01

    This report provides a summary that reflects the progress and status of proposed regulatory design criteria for advanced non-light water reactor (LWR) designs in accordance with the Level 3 milestone M3AT-17IN2001013 in work package AT-17IN200101. These criteria have been designated as advanced reactor design criteria (ARDC) and they provide guidance to future applicants for addressing the general design criteria (GDC) that are currently applied specifically to LWR designs. This report provides a summary of Phase 2 activities related to the various tasks associated with ARDC development and the subsequent development of ARDC regulatory guidance for sodium fast reactor (SFR) and modular high-temperature gas-cooled reactor (HTGR) designs. Status Report Organization: Section 2 discusses the origin of the GDC and their application to LWRs. Section 3 addresses the objective of this initiative and how it benefits the advanced non-LWR reactor vendors. Section 4 discusses the scope and structure of the initiative. Section 5 provides background on the U.S. Department of Energy (DOE) ARDC team’s original development of the proposed ARDC that were submitted to the NRC for consideration. Section 6 provides a summary of recent ARDC Phase 2 activities. Appendices A through E document the DOE ARDC team’s public comments on various sections of the NRC’s draft regulatory guide DG–1330, “Guidance for Developing Principal Design Criteria for Non-Light Water Reactors.”

  20. Reliability history of the Apollo guidance computer

    Science.gov (United States)

    Hall, E. C.

    1972-01-01

    The Apollo guidance computer was designed to provide the computation necessary for guidance, navigation and control of the command module and the lunar landing module of the Apollo spacecraft. The computer was designed using the technology of the early 1960's and the production was completed by 1969. During the development, production, and operational phase of the program, the computer has accumulated a very interesting history which is valuable for evaluating the technology, production methods, system integration, and the reliability of the hardware. The operational experience in the Apollo guidance systems includes 17 computers which flew missions and another 26 flight type computers which are still in various phases of prelaunch activity including storage, system checkout, prelaunch spacecraft checkout, etc. These computers were manufactured and maintained under very strict quality control procedures with requirements for reporting and analyzing all indications of failure. Probably no other computer or electronic equipment with equivalent complexity has been as well documented and monitored. Since it has demonstrated a unique reliability history, it is important to evaluate the techniques and methods which have contributed to the high reliability of this computer.