WorldWideScience

Sample records for e region

  1. Electrondynamics of the auroral E region

    International Nuclear Information System (INIS)

    Kirkwood, Sheila.

    1990-10-01

    This study concentrates on the signatures of the interaction process seen closest to the Earth - i.e. in the region where the visible aurora is produced. A number of experimental investigations are presented which look at details of the dynamics and electrodynamics of auroral ionisation features in the ionospheric E region. The studies are based primarily on measurement with the EISCAT UHF incoherent scatter radar which is located in northern Scandinavia. Initial calibration of the radar, and some measurements of the properties of the background atmosphere are described first. These are a necessary basis for the detailed studies which follow, which are of two aspects of auroral electrodynamics - substorms and aurorally-associated sporadic E layers. For the substorm studies, all-sky camera observations of the aurora over Scandinavia and ultra-violet images from the Viking satellite are used to identify the auroral forms corresponding to EISCAT measurements. This allows the determination of representative conductivities for the different auroral features which are characteristic of the substorm development. These conductivities are an important input for modelling studies of the electric current systems and have not previously been measured directly. Particle measurements from the Viking satellite are used together with EISCAT to determine the origin of the particles precipitated into the ionosphere during the energy-storage phase prior to the substorm. The sporadic E layers studies address the question of how ion layers and associated neutral sodium layers can be produced by some process which is common in association with auroral activity. Two candidates are considered - gravity waves and electric fields. (author)

  2. Celso Furtado e o desenvolvimento regional

    Directory of Open Access Journals (Sweden)

    Clélio Campolina Diniz

    2009-08-01

    Full Text Available This text analyzes the contributions by Celso Furtado to interpreting the determinants of regional inequalities and to the formulation of development policies for less developed regions. It uses a backdrop the theoretical antecedents and principal global experiences of regional development policies, which served as a reference for Celso Furtado. It shows Furtado's originality when he linked questions of regional inequality with the nature of underdeveloped structures. It shows the theoretical and empirical foundations in the analysis of the Northeast question, guidelines for the future SUDENE, political pressures and the insufficiencies in the way development policies for the Northeast are carried out. Finally, it shows how Furtado's positions are still relevant, whether in the formulations prior to the creation of SUDENE or in the later theoretical developments. In these, Furtado overcomes the notion of region and begins to examine spatial structures; he introduces the central role of urban nodes, of their hierarchies and articulations; in other words, the role of the urban network in the command and structuring of the territory; of the central role of technology and innovation processes, and finally, of the need for an interdisciplinary effort for both understanding regional problems as well as for the formulation of policies and their implementation.

  3. Medical e-commerce for regional Australia.

    Science.gov (United States)

    Kumar, D K; Mikelaitis, P

    2001-12-01

    The residents of rural and regional Australia have less access to health care services than in capital cities. There is a reluctance of General Practitioners to practice in the country. New information technology and government initiatives are now addressing this problem. High bandwidth videoconferencing is now being routinely used to provide psychiatric consultations to areas without this service. But this (like many other implementations of telecommunication technologies to health) has resulted in loss of revenue to regional Australia while benefiting capital cities. Thus, the current implementation of telecommunication technology to health has resulted in loss of revenue of the regions while increasing the bias towards the cities. Further, the system is not economically viable and requires the Government to inject funds for the smooth operation of the system. This paper proposes the use of telecommunication technology for enabling the communities of regional Australia to access health facilities via physical and virtual clinics. The proposed technique is self supporting and is based in the country with the intent to prevent the drain of resources from regional Australia. The technique attempts to eradicate the problem at the root level by providing a business opportunity that is based in and to cater for the needs of the remote communities. The proposed system would provide health services by physical and virtual clinics and while serving the communities would be profit centres- and thus attracting doctors and other resources to the remote communities.

  4. (e,2e) investigations in the autoionising region of helium

    International Nuclear Information System (INIS)

    Samardzic, O.; Brunger, M.J.; Weigold, E.

    1995-11-01

    In the present work values of the triple differential cross section parameters, which describe the shape and magnitude of the profile of each resonance r, along with values for the direct ionisation cross section and the post-collision interaction (PCI) related shift, were determined for the (2s 2 ) 1 S, (2p 2 ) 1 D and (2s2p) 1 P resonances in helium at E 0 = 94.6, 96.6 and 99.6 eV,θ sc =20 deg and -θ ej ranging from 30 deg to 135 deg. The results showed a strong dependence on the momenta of the ejected electrons, and also show strong interference between the direct and resonance amplitudes. In fact the interference, both constructive and destructive, between these amplitudes dominates the behaviour of the cross sections, producing quite marked oscillations in the resonance parameters. The theoretical calculations of Kheifets (1993) are also presented and generally fair agreement is found between theory and experiment. This indicates the theory is doing an adequate job in calculating both the direct ionisation and autoionisation amplitudes and consequently their interference. Where discrepancies between theory and experiment, for the resonance parameters, do exist they seem to occur at the same angles θ ej where PCI effects are observed. 13 refs., 1 tab., 10 figs

  5. Characteristics of low latitude ionospheric E-region irregularities ...

    Indian Academy of Sciences (India)

    154°E, dip angle = 37.3°, sub-ionospheric dip = 34°) have been analyzed to study the behaviour of ionospheric E-region irregularities during the active solar and magnetic periods. The autocorrelation functions, power spectral densities, signal de-correlation times are computed to study the temporal features of ionospheric ...

  6. CERVEJA ARTESANAL E DESENVOLVIMENTO REGIONAL EM SANTA CATARINA (BRASIL)

    OpenAIRE

    Valdinho Pellin; Oklinger Mantovaneli Jr.

    2016-01-01

    Discussões relacionadas ao fortalecimento do desenvolvimento regional tem estimulado um debate em relação a contribuições que Indicações Geográficas (IGs) podem oferecer ao desenvolvimento. IGs se constituem em elemento de identificação de produtos ou serviços com seus territórios e podem oferecer contribuições importantes para o desenvolvimento regional, agregando valor aos produtos, facilitando o acesso a novos mercados e valorizando tradições locais. Este artigo procura discutir a importân...

  7. Electron temperature in the E-region of the ionosphere

    International Nuclear Information System (INIS)

    Zalpuri, K.S.; Oyama, K.-I.

    1991-06-01

    Various heating and cooling mechanisms which are operative in the lower E-region are discussed and their relative importance in different altitude range is shown. These heating and cooling rates are then used to derive the electron temperature T e . The calculated values of electron temperature are found to be higher than neutral temperature through out the altitude range 100 ∼ 150 km, with the difference increasing with increase in altitude. However, compared to observed values of T e , the calculated values are still smaller below about 130 km. Above this altitude, the calculated values become larger. Estimation of T e for different, suggested values of heating efficiency due to dissociative recombination, show that T e profile obtained even be assuming a constant value of 1.3 eV is in fairly good agreement with those derived based on variable values of this parameter. (author)

  8. Brasil, Mercosul e a segurança regional

    Directory of Open Access Journals (Sweden)

    Amâncio Jorge de Oliveira

    2000-12-01

    Full Text Available O objetivo deste artigo é analisar a evolução de um regime hemisférico de segurança tendo em vista duas questões fundamentais: o impacto do Mercosul no equilíbrio geopolítico continental e o papel do Brasil como ator-chave na conformação deste arranjo hemisférico de segurança. Nossa hipótese é de que, tanto na dimensão regional, quanto global, o Brasil tem atuado no sentido de contrabalançar a hegemonia norte-americana, reforçando a correlação entre o status de potência regional e o cálculo de opções internacionais.The main purpose of this article is to analyse the evolution of a hemispheric regime of security using two basic issues: the impact of Mercosur in the regional geopolitical balance and the role of Brazil as a key-actor in the establishment of this agenda for regional security. Our hypothesis is that Brazil, as much in the regional, as in the global dimension, has acted so as to counterbalance the United States hegemony, strengthening the correlation between the status of regional power and the calculus of international options.

  9. CERVEJA ARTESANAL E DESENVOLVIMENTO REGIONAL EM SANTA CATARINA (BRASIL

    Directory of Open Access Journals (Sweden)

    Valdinho Pellin

    2016-12-01

    Full Text Available Discussões relacionadas ao fortalecimento do desenvolvimento regional tem estimulado um debate em relação a contribuições que Indicações Geográficas (IGs podem oferecer ao desenvolvimento. IGs se constituem em elemento de identificação de produtos ou serviços com seus territórios e podem oferecer contribuições importantes para o desenvolvimento regional, agregando valor aos produtos, facilitando o acesso a novos mercados e valorizando tradições locais. Este artigo procura discutir a importância da cerveja artesanal no contexto do desenvolvimento regional em Santa Catarina. Para tanto explora como objetivos específicos: (i caracterizar as discussões que estão ocorrendo em torno do reconhecimento da IG para chope e cerveja artesanal na região de Blumenau (SC; (ii identificar contribuições e desafios para o Desenvolvimento Regional de um possível reconhecimento da IG; e (iii caracterizar limites e potencialidades sinalizados pela iniciativa em curso. Metodologicamente trata-se de pesquisa analítica e descritiva baseada em estudo de caso de natureza exploratória. Como instrumento de coleta de dados se realizou entrevistas semiestruturadas com gestores de micro cervejarias artesanais da região e atores públicos e privados envolvidos diretamente nas discussões. Além destas fontes primárias o estudo fundamentou-se em fontes consubstanciadas pelos documentos produzidos nas reuniões de trabalho realizadas até o presente. Os principais resultados de análise destacam que um possível reconhecimento da IG poderia contribuir para o fortalecimento do setor, aumentando a competitividade, além de fortalecer a atividade turística na região. Entretanto para isso, alguns conflitos, surgidos no âmbito das discussões, precisam ser assumidos, superados ou mitigados

  10. SEE-GRID eInfrastructure for Regional eScience

    Science.gov (United States)

    Prnjat, Ognjen; Balaz, Antun; Vudragovic, Dusan; Liabotis, Ioannis; Sener, Cevat; Marovic, Branko; Kozlovszky, Miklos; Neagu, Gabriel

    In the past 6 years, a number of targeted initiatives, funded by the European Commission via its information society and RTD programmes and Greek infrastructure development actions, have articulated a successful regional development actions in South East Europe that can be used as a role model for other international developments. The SEEREN (South-East European Research and Education Networking initiative) project, through its two phases, established the SEE segment of the pan-European G ´EANT network and successfully connected the research and scientific communities in the region. Currently, the SEE-LIGHT project is working towards establishing a dark-fiber backbone that will interconnect most national Research and Education networks in the region. On the distributed computing and storage provisioning i.e. Grid plane, the SEE-GRID (South-East European GRID e-Infrastructure Development) project, similarly through its two phases, has established a strong human network in the area of scientific computing and has set up a powerful regional Grid infrastructure, and attracted a number of applications from different fields from countries throughout the South-East Europe. The current SEEGRID-SCI project, ending in April 2010, empowers the regional user communities from fields of meteorology, seismology and environmental protection in common use and sharing of the regional e-Infrastructure. Current technical initiatives in formulation are focusing on a set of coordinated actions in the area of HPC and application fields making use of HPC initiatives. Finally, the current SEERA-EI project brings together policy makers - programme managers from 10 countries in the region. The project aims to establish a communication platform between programme managers, pave the way towards common e-Infrastructure strategy and vision, and implement concrete actions for common funding of electronic infrastructures on the regional level. The regional vision on establishing an e

  11. Synchrotron Radiation in eRHIC Interaction Region

    CERN Document Server

    Beebe-Wang, Joanne; Montag, Christoph; Rondeau, Daniel J; Surrow, Bernd

    2005-01-01

    The eRHIC currently under study at BNL consists of an electron storage ring added to the existing RHIC complex. The interaction region of this facility has to provide the required low-beta focusing while accommodating the synchrotron radiation generated by beam separation close to the interaction point. In the current design, the synchrotron radiation caused by 10GeV electrons bent by low-beta triplet magnets will be guided through the interaction region and dumped 5m downstream. However, it is unavoidable to stop a fraction of the photons at the septum where the electron and ion vacuum system are separated. In order to protect the septum and minimize the backward scattering of the synchrotron radiation, an absorber and collimation system will be employed. In this paper, we first present the overview of the current design of the eRHIC interaction region with special emphasis on the synchrotron radiation. Then the initial design of the absorber and collimation system, including their geometrical and physical p...

  12. Electric field measurements in the auroral E region

    International Nuclear Information System (INIS)

    Mahon, H.P.; Smiddy, M.; Sagalyn, R.C.

    1975-01-01

    Dipole electric field, positive ion and electron densities and temperatures, vehicle potential, and plasma sheath measurements have been made in the auroral E region by means of rockets flown from Fort Churchill, Canada. These results are described and compared over the altitude region 100 to 165 km. On a rocket flight launched on 10 December 1969 during very quiet conditions, adjacent to a stable, low intensity auroral arc, the plasma density and temperatures are found to be high and the electric fields large and steady. Electric field components of the order of -17 mv m -1 to +6 mv m -1 were measured along the Earth's magnetic field. The plasma results indicate that these fields may be contributing to enhanced electron temperatures. On a flight of 9 March 1970 during a large magnetic storm with widespread auroral activity, lower plasma densities and temperatures and much smaller and more erratic electric fields were observed with no significant component parallel to the magnetic field. (auth)

  13. Energetics and structure of the lower E region associated with sporadic E layer

    Directory of Open Access Journals (Sweden)

    K.-I. Oyama

    2008-09-01

    Full Text Available The electron temperature (Te, electron density (Ne, and two components of the electric field were measured from the height of 90 km to 150 km by one of the sounding rockets launched during the SEEK-2 campaign. The rocket went through sporadic E layer (Es at the height of 102 km–109 km during ascent and 99 km–108 km during decent, respectively. The energy density of thermal electrons calculated from Ne and Te shows the broad maximum in the height range of 100–110 km, and it decreases towards the lower and higher altitudes, which implies that a heat source exists in the height region of 100 km–110 km. A 3-D picture of Es, that was drawn by using Te, Ne, and the electric field data, corresponded to the computer simulation; the main structure of Es is projected to a higher altitude along the magnetic line of force, thus producing irregular structures of Te, Ne and electric field in higher altitude.

  14. Evidence of the Dampening Effect of Dense E-region Structures on E-F Coupling

    Science.gov (United States)

    Helmboldt, J.

    2012-12-01

    Results from a combination of instruments including ionosondes, GPS receivers, the Very Large Array (VLA), and the Long Wavelength Array (LWA) are used to demonstrate the role structure within the E-region plays in coupling between instabilities within the E and F regions at midlatitudes. VLA observations of cosmic sources at 74 MHz during summer nighttime in 2002 detected northwest-to-southeast aligned wavefronts, consistent with medium-scale traveling ionospheric disturbances (MSTIDs). These waves were only found when contemporaneous observations from nearby ionosondes detected echoes from sporadic-E layers. However, when the peak density of these layers was high (foEs> 3 MHz), there were no MSTIDs detected. Similar results are presented using the first station of the LWA, LWA1, to perform all-sky imaging of dense E-region structures (sporadic-E "clouds") via coherent scattering of distant analog TV broadcasts at 55 MHz. These observations were conducted during summer/autumn 2012 and include simultaneous GPS-based observations of F-region disturbances.Left: LWA1 all-sky image of ionospheric echoes of analog TV transmissions at 55.25 MHz. Right: Doppler speed maps for the brightest echoes.

  15. Low-frequency electrostatic waves in the ionospheric E region

    Energy Technology Data Exchange (ETDEWEB)

    Krane, B [NDRE, Box 25, N-2027 Kjeller (Norway); Pecseli, H L; Sato, H [Physics Department, University of Oslo, PO Box 1048 Blindern, N-0316 Oslo (Norway); Trulsen, J [Institute of Theoretical Astrophysics, University of Oslo, PO Box 1029 Blindern, N-0315 Oslo (Norway); Wernik, A W, E-mail: hans.pecseli@fys.uio.n [Space Research Center, Polish Academy of Sciences, ul. Bartycka 18a, 00-716 Warsaw (Poland)

    2010-06-15

    Low-frequency electrostatic waves in the ionospheric E region are studied by analyzing data obtained by instrumented rockets. We identify the origin of the enhanced fluctuation level to be the Farley-Buneman instability. The basic information on instability, such as altitude varying spectra and speed of propagation are obtained. Comparison of power spectra for the fluctuations in plasma density and electrostatic potential, respectively, provides information on the electron dynamics. A bispectral analysis gives indications of phase-coherent couplings within the wave spectrum, while higher order structure functions indicate some intermittent features of the turbulence.

  16. E-region echo characteristics governed by auroral arc electrodynamics

    Directory of Open Access Journals (Sweden)

    S. E. Milan

    Full Text Available Observations of a pair of auroral arc features by two imagers, one ground- and one space-based, allows the associated field-aligned current (FAC and electric field structure to be inferred. Simultaneous observations of HF radar echoes provide an insight into the irregularity-generating mechanisms. This is especially interesting for the E-region echoes observed, which form the focus of our analysis, and from which several conclusions can be drawn, summarized as follows. Latitudinal variations in echo characteristics are governed by the FAC and electric field background. Particularly sharp boundaries are found at the edges of auroral arcs. Within regions of auroral luminosity, echoes have Doppler shifts below the ion-acoustic speed and are proportional to the electric field, suggesting scatter from gradient drift waves. Regions of downward FAC are associated with mixed high and low Doppler shift echoes. The high Doppler shift component is greatly in excess of the ion-acoustic speed, but seems to be commensurate with the driving electric field. The low Doppler shift component appears to be much depressed below expectations.

    Key words. Ionosphere (ionospheric irregularities; electric fields and currents

  17. E-region echo characteristics governed by auroral arc electrodynamics

    Directory of Open Access Journals (Sweden)

    S. E. Milan

    2003-07-01

    Full Text Available Observations of a pair of auroral arc features by two imagers, one ground- and one space-based, allows the associated field-aligned current (FAC and electric field structure to be inferred. Simultaneous observations of HF radar echoes provide an insight into the irregularity-generating mechanisms. This is especially interesting for the E-region echoes observed, which form the focus of our analysis, and from which several conclusions can be drawn, summarized as follows. Latitudinal variations in echo characteristics are governed by the FAC and electric field background. Particularly sharp boundaries are found at the edges of auroral arcs. Within regions of auroral luminosity, echoes have Doppler shifts below the ion-acoustic speed and are proportional to the electric field, suggesting scatter from gradient drift waves. Regions of downward FAC are associated with mixed high and low Doppler shift echoes. The high Doppler shift component is greatly in excess of the ion-acoustic speed, but seems to be commensurate with the driving electric field. The low Doppler shift component appears to be much depressed below expectations.Key words. Ionosphere (ionospheric irregularities; electric fields and currents

  18. Evolution of the hepatitis E virus hypervariable region.

    Science.gov (United States)

    Smith, Donald B; Vanek, Jeff; Ramalingam, Sandeep; Johannessen, Ingolfur; Templeton, Kate; Simmonds, Peter

    2012-11-01

    The presence of a hypervariable (HVR) region within the genome of hepatitis E virus (HEV) remains unexplained. Previous studies have described the HVR as a proline-rich spacer between flanking functional domains of the ORF1 polyprotein. Others have proposed that the region has no function, that it reflects a hypermutable region of the virus genome, that it is derived from the insertion and evolution of host sequences or that it is subject to positive selection. This study attempts to differentiate between these explanations by documenting the evolutionary processes occurring within the HVR. We have measured the diversity of HVR sequences within acutely infected individuals or amongst sequences derived from epidemiologically linked samples and, surprisingly, find relative homogeneity amongst these datasets. We found no evidence of positive selection for amino acid substitution in the HVR. Through an analysis of published sequences, we conclude that the range of HVR diversity observed within virus genotypes can be explained by the accumulation of substitutions and, to a much lesser extent, through deletions or duplications of this region. All published HVR amino acid sequences display a relative overabundance of proline and serine residues that cannot be explained by a local bias towards cytosine in this part of the genome. Although all published HVRs contain one or more SH3-binding PxxP motifs, this motif does not occur more frequently than would be expected from the proportion of proline residues in these sequences. Taken together, these observations are consistent with the hypothesis that the HVR has a structural role that is dependent upon length and amino acid composition, rather than a specific sequence.

  19. Evolution of the hepatitis E virus hypervariable region

    Science.gov (United States)

    Vanek, Jeff; Ramalingam, Sandeep; Johannessen, Ingolfur; Templeton, Kate; Simmonds, Peter

    2012-01-01

    The presence of a hypervariable (HVR) region within the genome of hepatitis E virus (HEV) remains unexplained. Previous studies have described the HVR as a proline-rich spacer between flanking functional domains of the ORF1 polyprotein. Others have proposed that the region has no function, that it reflects a hypermutable region of the virus genome, that it is derived from the insertion and evolution of host sequences or that it is subject to positive selection. This study attempts to differentiate between these explanations by documenting the evolutionary processes occurring within the HVR. We have measured the diversity of HVR sequences within acutely infected individuals or amongst sequences derived from epidemiologically linked samples and, surprisingly, find relative homogeneity amongst these datasets. We found no evidence of positive selection for amino acid substitution in the HVR. Through an analysis of published sequences, we conclude that the range of HVR diversity observed within virus genotypes can be explained by the accumulation of substitutions and, to a much lesser extent, through deletions or duplications of this region. All published HVR amino acid sequences display a relative overabundance of proline and serine residues that cannot be explained by a local bias towards cytosine in this part of the genome. Although all published HVRs contain one or more SH3-binding PxxP motifs, this motif does not occur more frequently than would be expected from the proportion of proline residues in these sequences. Taken together, these observations are consistent with the hypothesis that the HVR has a structural role that is dependent upon length and amino acid composition, rather than a specific sequence. PMID:22837418

  20. La financial education nella regione Puglia: analisi e prospettive di intervento

    OpenAIRE

    A. Garzoni; V. Nastasi

    2010-01-01

    Analisi del contesto e delle principali tematiche di financial education affrontate a livello internazionale e nazionale, valutazione delle opportunità e degli aspetti critici, il progetto pilota nella regione Puglia e le nuove idee di progetto da realizzare

  1. ENERGIA SOSTENIBILE: PIANIFICAZIONE STRATEGICA E PROGRAMMI ECONOMICI NELLA REGIONE LAZIO

    Directory of Open Access Journals (Sweden)

    Leonide Tocchi

    2017-06-01

    Full Text Available The new energy and regulatory scenarios on European and Italian level require a review of the regional energy strategies. Transitioning the global economy from fossil fuels to renewable energy sources has been identified as a key strategy for mitigating climate change. Energy sector transformation needs smart policies. The Lazio region is drawing up a new strategy for sustainable energy that aims to define the necessary conditions for development of a regional energy system increasingly turned to the use of renewable sources and efficient energy use as a means for greater environmental protection, in particular for the purpose of reduction of greenhouse gases (GHG. The strategy aims to facilitate the transition to a low carbon economy by increasing energy production from renewable sources, fostering a green economic recovery and the creation of green jobs in Lazio Region.

  2. A preliminary comparison of F region plasma drifts and E region irregularity drifts in the auroral zone

    International Nuclear Information System (INIS)

    Ecklund, W.L.; Balsley, B.B.; Carter, D.A.

    1977-01-01

    During several days in April--May 1976 the Chatanika, Alaska, incoherent scatter radar and a temporary Doppler auroral radar located at Aniak, Alaska, were directed toward ionospheric volumes along a common magnetic field line in order to compare E region and F region drifts and associated electric fields. The Chatanika radar measured F region plasma drifts via the incoherent scatter technique, while the Aniak radar measured the drifts of E region irregularities (i.e., the radar aurora). The radar geometry was arranged so that both radars measured approximately the same velocity component of a magnetically westward or eastward motion. Preliminary data show good agreement between the drift velocity components measured by the two techniques during most of the experimental period. This result indicates that relatively modest auroral radar systems may be used, with some qualifications, to determine auroral electric fields

  3. Banche, territorio e sviluppo (Banks, Regions and Development

    Directory of Open Access Journals (Sweden)

    Pietro Alessandrini

    2003-03-01

    Full Text Available From the 1980s onwards the banking sectors in all the industrialised countries have been experiencing intense restructuring, aggregation and consolidation, radically changing their ownership structures and geography. Whatever the reasons behind such restructuring processes, the globalisation of the credit markets, the consolidation of banking structures, the removal of barriers to the free location of banks and their penetration of peripheral markets pose two main questions. Will integration of the banking systems lead to a narrowing or a widening of the development gap between regions? What relations will there be between financial centres and the periphery, and how will financial labour be divided between national (international banks and local (regional banks? The aim of this paper is to address such questions in the light of recent developments in the theoretical and empirical literature on financial integration.

  4. Banche, territorio e sviluppo (Banks, Regions and Development

    Directory of Open Access Journals (Sweden)

    Pietro Alessandrini

    2012-04-01

    Full Text Available From the 1980s onwards the banking sectors in all the industrialised countries have been experiencing intense restructuring, aggregation and consolidation, radically changing their ownership structures and geography. Whatever the reasons behind such restructuring processes, the globalisation of the credit markets, the consolidation of banking structures, the removal of barriers to the free location of banks and their penetration of peripheral markets pose two main questions. Will integration of the banking systems lead to a narrowing or a widening of the development gap between regions? What relations will there be between financial centres and the periphery, and how will financial labour be divided between national (international banks and local (regional banks? The aim of this paper is to address such questions in the light of recent developments in the theoretical and empirical literature on financial integration.  JEL Codes: G21, G28, G34Keywords: Bank, Banking, Credit, Globalization, Restructuring

  5. Bienestar económico regional: un enfoque comparativo entre regiones españolas e italianas

    OpenAIRE

    Pilar Murias Fernández; Fidel Martínez Roget; Simone Novello

    2010-01-01

    Este trabajo propone una visión revisada del bienestar económico regional. Trabajos recientes en economía regional han mostrado su desacuerdo con la noción tradicional de bienestar económico que considera únicamente renta per cápita. A través de la comparación de regiones españolas e italianas y usando un enfoque basado en el Análisis Envolvente de Datos, este trabajo sugiere un indicador sintético de bienestar regional basado en las cuatro componentes de Osberg (1985): capacidad de consumo, ...

  6. Energetics and structure of the lower E region associated with sporadic E layer

    Directory of Open Access Journals (Sweden)

    K.-I. Oyama

    2008-09-01

    Full Text Available The electron temperature (Te, electron density (Ne, and two components of the electric field were measured from the height of 90 km to 150 km by one of the sounding rockets launched during the SEEK-2 campaign. The rocket went through sporadic E layer (Es at the height of 102 km–109 km during ascent and 99 km–108 km during decent, respectively. The energy density of thermal electrons calculated from Ne and Te shows the broad maximum in the height range of 100–110 km, and it decreases towards the lower and higher altitudes, which implies that a heat source exists in the height region of 100 km–110 km. A 3-D picture of Es, that was drawn by using Te, Ne, and the electric field data, corresponded to the computer simulation; the main structure of Es is projected to a higher altitude along the magnetic line of force, thus producing irregular structures of Te, Ne and electric field in higher altitude.

  7. Role of e-learning information systems in regional development

    Directory of Open Access Journals (Sweden)

    Maria ANDRONIE

    2010-09-01

    The Information Communication Technology – ICT, an useful strategy for the education system improvement, is a means enabling the students develop their fundamental knowledge and the necessary competences in various fields in a knowledge-based economy. Computer skills become a “must”. We need to understand the way to improve the education system of an institution by implementing these technologies, in general, and the e-Learning systems, in particular. In this context, the information systems are the driver of a global education.

  8. Cadenas de valor e instrumentos para el desarrollo regional

    OpenAIRE

    Victoria, María Adriana

    2013-01-01

    Partiendo de la cadena productiva se analiza sus diferencias con la “cadena de valor” y el “valor agregado” y se rescata la importancia de las “cadenas de valor” para el “desarrollo regional”, citándose algunas “cadenas de valor regionales”. A modo de conclusión se señala que se necesita: 1) la búsqueda de articulaciones para dar mayor valor agregado a aquellos productos que hoy se producen básicamente en muchas de las “economías regionales” que tiene nuestro país. 2) la generación e integrac...

  9. E qual o lugar da Geografia Regional no contexto atual da Geografia?

    OpenAIRE

    Serpa, Angelo

    2001-01-01

    Este artigo é uma revisão bibliográfica comentada sobre o papel da Geografia Regional no contexto da ciência geográfico contemporânea, resultado das reflexões e experiência como professor, desde 1997, das disciplinas Geografia Regional I e II (do curso de graduação em Geografia) e Evolução e Organização do Espaço Regional (do curso de Mestrado em Geografia), na Universidade Federal da Bahia.

  10. Effects of a conducting E layer on classical F region cross-field plasma diffusion

    International Nuclear Information System (INIS)

    Vickrey, J.F.; Kelley, M.C.

    1982-01-01

    The rate of cross-field plasma diffusion in the F region ionosphere is significantly increased when the magnetic field lines thread a highly conducting E region below. This reduces the lifetime of small-scale F region electron density irregularities in the polar ionosphere where the presence of a highly conducting E region is comonplace. A simple mmodel is developed to describe the effects of a conducting E layer on classical F region plasma diffusion. In the absence of an E region, the difference in ion and electron diffusion rates leads to a charge separation and, hence, to an electrostatic field that retards ion diffusion. When the highly conducting magnetic field lines are tied to a conducting E region, however, electrons can flow along B to reduce the ambipolar diffusion electric field, and ions can proceed perpendicular to B at a rate approaching their own (higher) diffusion velocity. It is shown that the enhanced total diffusion rate that results depends strongly on the height of the F layer and on the ratio of the E to F region Pedersen conductivities

  11. Equatorial E Region Electric Fields and Sporadic E Layer Responses to the Recovery Phase of the November 2004 Geomagnetic Storm

    Science.gov (United States)

    Moro, J.; Resende, L. C. A.; Denardini, C. M.; Xu, J.; Batista, I. S.; Andrioli, V. F.; Carrasco, A. J.; Batista, P. P.; Schuch, N. J.

    2017-12-01

    Equatorial E region electric fields (EEFs) inferred from coherent radar data, sporadic-E (Es) layers observed from a digital ionosonde data, and modeling results are used to study the responses of the equatorial E region over São Luís (SLZ, 2.3°S, 44.2°W, -7° dip angle), Brazil, during the super storm of November 2004. The EEF is presented in terms of the zonal (Ey) and vertical (Ez) components in order to analyze the corresponding characteristics of different types of Es seen in ionograms and simulated with the E region ionospheric model. We bring out the variabilities of Ey and Ez components with storm time changes in the equatorial E region. In addition, some aspects of the electric fields and Es behavior in three cases of weak, very weak, and strong Type II occurrences during the recovery phase of the geomagnetic storm are discussed. The connection between the enhanced occurrence and suppressions of the Type II irregularities and the q-type Es (Esq) controlled by electric fields, with the development or disruption of the blanketing sporadic E (Esb) layers produced by wind shear mechanism, is also presented. The mutual presence of Esq along with the Esb occurrences is a clear indicator of the secular drift of the magnetic equator and hence that of the equatorial electrojet (EEJ) over SLZ. The results show evidence about the EEJ and Es layer electrodynamics and coupling during geomagnetic disturbance time electric fields.

  12. Comparison of E-Commerce behaviour among women consumers of Balkan and Baltic Regions

    OpenAIRE

    Polychronidou Persefoni; Valsamidis Stavros; Florou Giannoula; Karasavvoglou Anastasios

    2011-01-01

    Nowadays, more and more consumers prefer to make their shopping via Internet. Researchers wish to study the e-commerce behaviour and the factors influencing consumer’s attitude while shopping on line. This paper investigates the differences and similarities of women’s behaviour toward e-commerce in two culturally different Europe regions; the Balkans and the Baltic regions. Some attributes such as trust in vendor, trust in transactions, language, culture, age or education and their possible i...

  13. Transcriptional activation by the E1A regions of adenovirus types 40 and 41

    NARCIS (Netherlands)

    Loon, A.E. van; Gilardi, P.; Perricaudet, M.; Rozijn, Th. H.; Sussenbach, J.S.

    In order to establish whether the poor growth of the two fastidious adenoviruses types 40 and 41 (Ad40 and Ad41) in HeLa cells is due to a reduced trans-activation by the early region to (E1A), we have determined the trans-activating effect of this region on the expression of the chloramphenicol

  14. Unequal distribution of RT-PCR artifacts along the E1-E2 region of Hepatitis C virus.

    Science.gov (United States)

    Domingo-Calap, Pilar; Sentandreu, Vicente; Bracho, Maria Alma; González-Candelas, Fernando; Moya, Andrés; Sanjuán, Rafael

    2009-10-01

    Although viral variability studies have focused traditionally on consensus sequences, the relevance of molecular clone sequences for studying viral evolution at the intra-host level is being increasingly recognized. However, for this approach to be reliable, RT-PCR artifacts do not have to contribute excessively to the observed variability. Molecular clone sequences were obtained from an in vitro transcript to estimate the maximum error rate associated to RT-PCR for the Hepatitis C virus (HCV) E1-E2 region. On average, the frequency of RT-PCR errors was one order of magnitude lower than the level of intra-host genetic variability observed in samples from an HCV outbreak. However, RT-PCR errors were not distributed evenly along the E1-E2 region and were concentrated heavily in the hypervariable region 2 (HVR 2). Although it is concluded that RT-PCR molecular clone sequences are reliable, these results warn against extrapolation of RT-PCR error rates to different genome regions. The data suggest that the RNA sequence context or secondary structure can determine the fidelity of in vitro transcription or reverse transcription. Potentially, these factors might also modify the fidelity of the viral polymerase.

  15. Human food chain contamination. Dairy products in 28 regions of the E.E.C. in 1977

    International Nuclear Information System (INIS)

    Obino, A.-M.; Garnier, Arlette; Brenot, Jean.

    1981-08-01

    Global and individual levels of contamination by cesium 137 and strontium 90 resulting from consumption of dairy products in 28 regions of the European Economical Community are evaluated. We begin with economical considerations: production, industry, distribution and consumption. Regional exchanges, using 1977 statistical data, are then established for the following products: crude milk, skim milk, consumption milk, fresh products, butter, cheese and powder. Finally, various contamination results are presented, associated with the observed concentrations of cesium 137 and strontium 90 in milk in the E.E.C. during 1977, and in the hypothesis of highly contaminated regions. Some results are expressed as concentrations in the various dairy products after transformations and exchanges, others are expressed as individual ingested activities. A sensitivity analysis is used to assess the exchange effect [fr

  16. 7 CFR Exhibit E to Subpart E of... - List of Regional Offices, Office of Federal Contract Compliance Programs (OFCCP), U.S. Department...

    Science.gov (United States)

    2010-01-01

    ... Compliance Programs (OFCCP), U.S. Department of Labor (USDL) E Exhibit E to Subpart E of Part 1901... REGULATIONS PROGRAM-RELATED INSTRUCTIONS Civil Rights Compliance Requirements Pt. 1901, Subpt. E, Exh. E Exhibit E to Subpart E of Part 1901—List of Regional Offices, Office of Federal Contract Compliance...

  17. Charmed baryon production in e/sup +/e/sup -/ annihilation in the upsilon region

    International Nuclear Information System (INIS)

    Mestayer, M.D.

    1985-01-01

    The author has observed the production of Λ/sub c/ baryons in e/sup +/e/sup -/ annihilation by reconstructing their mass from the decay mode Λ/sub c/ → Λπ/sup +/π/sup +/π/sup -/. They compare the production rates of the Λ/sub c/ with that of the D/sup +/ meson, which they detect through its K-bar 0 π/sup +/π/sup +/π/sup -/ decay mode. The similarity of the kinematics of the two decays implies that much of the systematic uncertainty in detection efficiency cancels in the ratio of the rates, thereby allowing a comparison of charmed baryon and meson hardonization

  18. A classification of spectral populations observed in HF radar backscatter from the E region auroral electrojets

    Directory of Open Access Journals (Sweden)

    S. E. Milan

    2001-02-01

    Full Text Available Observations of HF radar backscatter from the auroral electrojet E region indicate the presence of five major spectral populations, as opposed to the two predominant spectral populations, types I and II, observed in the VHF regime. The Doppler shift, spectral width, backscatter power, and flow angle dependencies of these five populations are investigated and described. Two of these populations are identified with type I and type II spectral classes, and hence, are thought to be generated by the two-stream and gradient drift instabilities, respectively. The remaining three populations occur over a range of velocities which can greatly exceed the ion acoustic speed, the usual limiting velocity in VHF radar observations of the E region. The generation of these spectral populations is discussed in terms of electron density gradients in the electrojet region and recent non-linear theories of E region irregularity generation.Key words. Ionosphere (ionospheric irregularities

  19. A classification of spectral populations observed in HF radar backscatter from the E region auroral electrojets

    Directory of Open Access Journals (Sweden)

    S. E. Milan

    Full Text Available Observations of HF radar backscatter from the auroral electrojet E region indicate the presence of five major spectral populations, as opposed to the two predominant spectral populations, types I and II, observed in the VHF regime. The Doppler shift, spectral width, backscatter power, and flow angle dependencies of these five populations are investigated and described. Two of these populations are identified with type I and type II spectral classes, and hence, are thought to be generated by the two-stream and gradient drift instabilities, respectively. The remaining three populations occur over a range of velocities which can greatly exceed the ion acoustic speed, the usual limiting velocity in VHF radar observations of the E region. The generation of these spectral populations is discussed in terms of electron density gradients in the electrojet region and recent non-linear theories of E region irregularity generation.

    Key words. Ionosphere (ionospheric irregularities

  20. Sporadic-E and spread-F in high latitude region

    International Nuclear Information System (INIS)

    Tao, Kazuhiko

    1974-01-01

    The heretofore made morphological studies of sporadic-E and spread-F as the typical irregularities of electron density are reviewed. These phenomena have close correlation with other geophysical phenomena which occur in the atmosphere of superhigh altitude in high latitude region. Many of these phenomena occur from same causes. Although the quantitative data are insufficient, the sporadic-E and spread-F in high latitude region are supposed to be caused by the precipitating charged particles falling from magnetosphere. A system, which can observe such phenomena simultaneously using the measuring instruments carried by satellites in the atmosphere of high altitude over high latitude region, is desirable to solve such problems. In detail, the morphological study on sporadic-E obtained from the observation of vertically projected ionosphere and the morphological study on sporadic-E from the observation of forward scattering and slanting entrance are reviewed. The correlation of the occurrence frequency of sporadic-E with solar activity, geomagnetic activity and other phenomena was studied. The morphological study on spread-F occurrence is reviewed. The observation of the spread-F in high latitude region by the application of top side sounding is reviewed. The correlation of the sporadic-E and spread-F in high latitude region with other geophysical phenomena is discussed. Finally, the discrete phenomenon and the diffuse phenomenon are discussed too. (Iwakiri, K.)

  1. XANTHOLININI DELLA CINA, DELLA REGIONE ORIENTALE E DELL’AUSTRALIA. NUOVE SPECIE E NUOVI DATI GEONEMICI (COLEOPTERA, STAPHYLINIDAE

    Directory of Open Access Journals (Sweden)

    Arnaldo Bordoni

    2009-10-01

    Full Text Available L’autore descrive Erymus sinicus n. sp. del Fujian, affine a E. dalianus Bordoni dello Yunnan; Atopolinus brunneus n. sp. del Sichuan, affine a A. mirandus Bordoni del Meghalaya. Vengono forniti nuovi dati geonemici sugli Xantholinini della Cina e della Corea. L’autore descrive inoltre Thyreocephalus nigricantis n. sp. della Penisola Malese, affine a T. perakensis Bordoni della stessa Malesia, T. catastrophicus n. sp. delle isole della Sonda, caratteristico per la forma e la punteggiatura del capo, e Symilla cardamonica n. sp. del Tamil Nadu (India, affine a S. pulchra Bordoni e S. deplumis Bordoni dell’India meridionale e fornisce nuovi dati geonemici per altri Xantholinini della Regione Orientale. L’autore descrive infine Australinus bispinosus n. sp. dell’Australia, affine a A. sexsulciceps (Lea della stessa isola e Mitomorphus habbemanus n. sp. dell’Irian Jaya, isolato dalle congeneri per dimensioni, colorazione e punteggiatura; sono elencati nuovi dati geonemici relativi ad altri Xantholinini dell’Australia. Le seguenti specie sono nuove per le regioni indicate: Stenistoderus sinicus (Corea, Thyreocephalus amphidaseus (Pakistan, Adhavara ferrugunea (Cina, Phacophallus japonicus (Cambogia, Xanthophius filum (Cambogia, Yunna micophora (Shaanxi.

  2. Elites técnicas, Estado e desenvolvimento regional em Minas Gerais na Era Vargas

    Directory of Open Access Journals (Sweden)

    Daniel Henrique Diniz Barbosa

    Full Text Available Este texto aborda o processo de desenvolvimento regional encetado em Minas Gerais, com particular ênfase na participação do corpo técnico regional ao longo das décadas de 1930 e 1940. Trata-se de um período de relevantes transformações no âmbito do poder público, sobretudo no tocante ao papel desempenhado pela ideologia e prática do planejamento e intervencionismo do Estado na esfera econômica, o que permitiu, no caso mineiro, a ascensão da categoria profissional do engenheiro às arenas decisórias do Estado, com repercussão na elaboração e tentativa de implantação de projetos voltados para o desenvolvimento econômico regional, notadamente nas áreas de agricultura e siderurgia. Este texto priorizará, para tanto, dois grupos específicos dentre essa elite técnica mineira: os ex-alunos da Escola de Minas de Ouro Preto e os alunos e professores da Escola Superior de Agricultura e Veterinária, de Viçosa.

  3. E-Government in the Asia-Pacific Region: Progress and Challenges

    Directory of Open Access Journals (Sweden)

    Clay Wescott

    2005-12-01

    Full Text Available This paper will focus on two issues: (i recent e-government progress and challenges, and (ii the practices regional organizations follow to cope with the challenges, while maximizing the benefits. Beginning with an overview of efforts to improve governance in the region, it then analyzes recent progress in the use of information and communication technology (ICT in the Asia-Pacific region to promote more efficient, cost-effective, and participatory government, facilitate more convenient government services, allow greater public access to information, and make government more accountable to citizens. Successful adoption of e-government presents major challenges. The paper concludes by examining the practices regional organizations follow to cope with the challenges, while maximizing the benefits.

  4. Memory and regional identity in Udihara’s cinema Memória e identidade regional no cinema de Udihara

    Directory of Open Access Journals (Sweden)

    Caio Júlio Cesaro

    2007-01-01

    Full Text Available The cinema produced by the Japanese immigrant Hikoma Udihara, for over 30 years, is a record of the first decades of colonization in Northern of Paraná. The content – a little more than 10 hours of images – constitutes essence of the memory and identity in the region. A file which, in spite of private and institutional efforts for its maintenance, is vanishing and deteriorating quickly. For this reason, urgent action is required for recuperation and preservation. O cinema produzido pelo imigrante japonês Hikoma Udihara, ao longo de mais de 30 anos, documenta as primeiras décadas da colonização do Norte do Paraná. O conteúdo – de pouco mais de dez horas de imagens – constitui-se essência da memória e da identidade da região. Um acervo que, apesar de esforços particulares e institucionais para sua manutenção, está esvaecendo e se desintegrando rapidamente. Em razão disso, necessita de ações urgentes de recuperação e preservação.

  5. Novo desenvolvimentismo e dinâmica urbano-regional no Brasil (2004-2012

    Directory of Open Access Journals (Sweden)

    Hipólita Siqueira

    2015-01-01

    Full Text Available As mudanças no contexto nacional e internacional impuseram novas questões ao debate sobre a dinâmica urbano-regional brasileira. Dentre elas, o aprofundamento da inserção internacional do País, tendo como base seu potencial de recursos naturais e sua articulação com o "efeito-China" na reconfiguração das relações internacionais, e o processo de desindustrialização, decorrente da especialização produtiva regressiva e da apreciação da taxa de câmbio. O objetivo deste artigo é examinar as lin-has gerais da dinâmica urbano-regional no âmbito das transformações na economia e sociedade brasileiras desde os anos 1980, especialmente no período pós-2004, em que ocorre uma retomada do crescimento econômico e dos gastos estatais. Entende-se que tal análise enfrenta desafios teórico-metodológicos importantes, sendo necessário o resgate de referenciais analíticos, como o da divisão espacial do trabalho para o entendimento das desigualdades regionais, e a (reformulação da questão regional brasileira.

  6. E-Business, the impact of regional growth on the improvement of Information and Communication Development

    Science.gov (United States)

    Setiawan, MI; Hasyim, C.; Kurniasih, N.; Abdullah, D.; Napitupulu, D.; Rahim, R.; Sukoco, A.; Dhaniarti, I.; Suyono, J.; Sudapet, IN; Nasihien, RD; Wulandari, DAR; Reswanda; Mudjanarko, SW; Sugeng; Wajdi, MBN

    2018-04-01

    ICT becomes a key element to improve industrial infrastructure efficiency and sustainable economic productivity. This study aims to analysis the impact of regional improvement on information and communication development in Indonesia. This research is a correlational study. Population of this research include 151 regions in Indonesia. By using a total sampling, there were 151 sample regions. The results show there are the strong impact of regional growth on increasing Gross Regional Domestic Product (GRDP) of information and communication. It can be seen from all regional improvement sub variables that have a high correlation in increasing GRDP of Information and Communication in Indonesia. Only two sub-variables that have low correlation to GRDP of Information and Communication variable i.e. GRDP of Agriculture, Forestry and Fishing (0.01) and GRDP of Mining and Quarrying (0.04). The correlation coefficient (R) is 0.981, means the variable of information and communication GRDP has a very strong correlation with regional growth variable. Thus the value of Adjusted R Square is 95.8%, means there are impact of regional growth variables in increasing GRDPof Information and Communication, while the increase of 4.2% of Information and Communication GRDP is influenced by other factors aside from regional improvement.

  7. E-commerce and territorial development in the Objective-1 spanish regions

    OpenAIRE

    Rodriguez Cohard, Juan Carlos; Bernal Jurado, Enrique

    2002-01-01

    The information and communication technologies constitute one of the main forces of the globalization. In this framework, the e-commerce takes advantage of Internet to improve the competitiveness of the companies and territories. In the nowadays scenario, the e-commerce opens development posibilities for the regions fewer developed, creating a virtual space that saves the geographical barriers. However, the use of its advantages requires infrastructures and equipment, organizational capacity ...

  8. Introduction of Open E-Learning System as a Factor of Regional Development

    OpenAIRE

    Tatiana Yuryevna Bystrova; Viola Anatoylevna Larionova; Michael Osborne; Anatoly Mikhaylovich Platonov

    2015-01-01

    The article analyses the economic and socio-cultural premises for introducing the open e-learning in the universities of the Ural region, as well as the potential economic effect of this type of educational activity. The article strives to prove a regular pattern of the universities’ transition to e-learning, also in connection with the changes of the educational paradigm and the nature of the educational system management. The hypothesis of the paper is connected with bringing the economic d...

  9. Geoestatística e avaliação Multicriterial no Processo de Planejamento e Desenvolvimento Local e Regional do Estado de São Paulo

    Directory of Open Access Journals (Sweden)

    Luís Eduardo Gregolin Grisotto

    2012-10-01

    Full Text Available O estudo teve como objetivo desenvolver procedimentos metodológicos, apoiando-se em ferramentas geoestatísticas e avaliação multicritério, para avaliar de forma integrada as condições de saúde, saneamento, ambiente e socioeconomia dos municípios do Estado de São Paulo. Foram efetuadas combinações entre análises espaciais, com base em Mapas de Kernel, e avaliação multicriterial para a demonstração de correlações entre índices de morbimortalidade e indicadores associados à cobertura por redes de água, esgoto e lixo, IDH, IPRS, PIB per capita, porte do município e taxa de urbanização. Os resultados indicaram que as ferramentas empregadas se mostraram eficazes na identificação das situações mais críticas e de maior complexidade, coincidentes com as áreas de menor dinamismo econômico situadas nas regiões sul, sudoeste e oeste do Estado. Conclui-se que o estado contribui para o aprimoramento do processo de planejamento municipal e regional, com vistas à redução das desigualdades e, também, ao desenvolvimento das áreas mais precárias.

  10. Multiple frequency radar observations of high-latitude E region irregularities in the HF modified ionosphere

    International Nuclear Information System (INIS)

    Noble, S.T.; Djuth, F.T.; Jost, R.J.

    1987-01-01

    In September 1983, experiments were conducted in Scandinavia using the high-power heating facility near Tromso, Norway. The purpose of the HF ionospheric modification experiments was to investigate the behavior of artificially produced E region irregularities at auroral latitudes. The majority of observations were made with backscatter radars operating at 46.9 and 143.8 MHz, but limited observations were also made at 21.4 and 140.0 MHz. These radars are sensitive to irregularities having scale lengths of between 1 and 7 m across the geomagnetic field lines. The growth and decay of the irregularities are scale length dependent with the shorter lengths growing and dissipating more rapidly than the longer lengths (e-folding growth times = 10 1 --10 2 ms; decay times = 10 2 --10 3 ms). During periods of full power ordinary mode heating, irregularities having peak cross sections of 10 4 m 2 at 46.9 MHz and 10 5 m 2 at 143.8 MHz are observed. However, the cross sections normally measured are 1 to 2 orders of magnitude smaller than the peak values. The cross sections are nonlinearly dependent on the HF power and begin to saturate at levels greater than 50--75 percent of full power. Past E and F region data from Arecibo are used in conjunction with the Tromso measurements to ascertain the relative roles played by various mechanisms in exciting irregularities. In the E region, the results tend to favor those instability processes which operate at the upper hybrid resonance level (e.g., thermal parametric and resonance instabilities) over those that operate at the reflection level (e.g., parametric decay instability). However, it is likely that anyh of the mechanisms studied could at times contribute to irregularity production in the E regions

  11. Ionospheric storm effects in the nighttime E region caused by neutralized ring current particles

    Directory of Open Access Journals (Sweden)

    R. Bauske

    1997-03-01

    Full Text Available During magnetic storms an anomalous increase in the ionization density of the nighttime E region is observed at low and middle latitudes. It has been suggested that this effect is caused by the precipitation of neutralized ring current particles. Here a coupled ring current decay-ionosphere model is used to confirm the validity of this explanation.

  12. Introduction of Open E-Learning System as a Factor of Regional Development

    Directory of Open Access Journals (Sweden)

    Tatiana Yuryevna Bystrova

    2015-12-01

    Full Text Available The article analyses the economic and socio-cultural premises for introducing the open e-learning in the Ural region, as well as the potential economic effect of this type of educational activity. The article strives to prove a regular pattern of the universities’ transition to e-learning, also in connection with the changes of the educational paradigm and the nature of the educational system management. The hypothesis of the paper is connected with bringing the economic dimension to a humanitarian concept of e-learning, which becomes more and more widespread. The methodology of the article is based on the recognition of the fact that the macroeconomic processes in the information society and the processes occurring in a particular industry — higher education — are of isomorphic nature. On the basis of the analysis of global experience and basic theoretical approaches to e-learning, including the Lifelong Learning concept, the authors make a conclusion of the progressive growth of interest in different countries and regions. The e-learning is treated primarily as a tool to improve quality and efficiency of the educational process. The accuracy of understanding functions and peculiarities of e-learning allows one to determine a positive economic effect of its application for the university, the region, and the employers. The article shows organisational mechanisms and financial model of implementing e-learning in the Ural Federal University. The description is made of the cost options for open-type e-learning course development, investment parameters for their establishment, as well as costs of implementing educational programmes with the application of e-learning. The analysis of the activities of Ural Federal University on implementing e-learning gives the opportunity to further imagine the effect from the introduction of e-learning in other universities in the region. The results of the research may be applied in the institutions of

  13. High Frequency Backscatter from the Polar and Auroral E-Region Ionosphere

    Science.gov (United States)

    Forsythe, Victoriya V.

    The Earth's ionosphere contains collisional and partially-ionized plasma. The electric field, produced by the interaction between the Earth's magnetosphere and the solar wind, drives the plasma bulk motion, also known as convection, in the F-region of the ionosphere. It can also destabilize the plasma in the E-region, producing irregularities or waves. Intermediate-scale waves with wavelengths of hundreds of meters can cause scintillation and fading of the Global Navigation Satellite System (GNSS) signals, whereas the small-scale waves (lambda Network (SuperDARN). The theoretical part of this work focuses on symmetry properties of the general dispersion relation that describes wave propagation in the collisional plasma in the two-stream and gradient-drift instability regimes. The instability growth rate and phase velocity are examined under the presence of a background parallel electric field, whose influence is demonstrated to break the spatial symmetry of the wave propagation patterns. In the observational part of this thesis, a novel dual radar setup is used to examine E-region irregularities in the magnetic polar cap by probing the E-region along the same line from opposite directions. The phase velocity analysis together with raytracing simulations demonstrated that, in the polar cap, the radar backscatter is primarily controlled by the plasma density conditions. In particular, when the E-region layer is strong and stratified, the radar backscatter properties are controlled by the convection velocity, whereas for a tilted E-layer, the height and aspect angle conditions are more important. Finally, the fundamental dependence of the E-region irregularity phase velocity on the component of the plasma convection is investigated using two new SuperDARN radars at high southern latitudes where plasma convection estimates are accurately deduced from all SuperDARN radars in the southern hemisphere. Statistical analysis is presented showing that the predominance of the

  14. RNA-Seq Mouse Brain Regions Expression Data Analysis: Focus on ApoE Functional Network

    Directory of Open Access Journals (Sweden)

    Babenko Vladimir N.

    2017-09-01

    Full Text Available ApoE expression status was proved to be a highly specific marker of energy metabolism rate in the brain. Along with its neighbor, Translocase of Outer Mitochondrial Membrane 40 kDa (TOMM40 which is involved in mitochondrial metabolism, the corresponding genomic region constitutes the neuroenergetic hotspot. Using RNA-Seq data from a murine model of chronic stress a significant positive expression coordination of seven neighboring genes in ApoE locus in five brain regions was observed. ApoE maintains one of the highest absolute expression values genome-wide, implying that ApoE can be the driver of the neighboring gene expression alteration observed under stressful loads. Notably, we revealed the highly statistically significant increase of ApoE expression in the hypothalamus of chronically aggressive (FDR < 0.007 and defeated (FDR < 0.001 mice compared to the control. Correlation analysis revealed a close association of ApoE and proopiomelanocortin (Pomc gene expression profiles implying the putative neuroendocrine stress response background of ApoE expression elevation therein.

  15. VHF and HF radar measurements of E and R region plasma drifts at the magnetic equator

    International Nuclear Information System (INIS)

    Viswanathan, K.S.; Namboothiri, S.P.; Rao, P.B.

    1992-01-01

    Simultaneous observations of E region horizontal irregularity drifts by VHF backscatter radar and of F region vertical plasma drift by HF Doppler radar conducted during daytime on a few magnetically quiet days at Trivandrum (dip 0.2 degree N) are presented. A comparative study of the two measurements indicates broadly (1) a resemblance in the daytime changes of the E-W component between the electric field and (2) evidence of quasi-periodic electric field variations with periods ranging mostly from 1 to 2 hours. The electric fields derived from HF Doppler radar observations are somewhat lower than those deduced by HVHF radar observations. The correlation coefficient for the variations of the electric fields measured by the two experimental techniques is found to be in the range of about 0.5 to 0.9. The observed difference in the E and F region electric fields at the magnetic equator is discussed in terms of the measurement uncertainties and the limitations involved in deriving E-W electric fields. The observations are suggestive of a latitudinal variation in the E-W component of the electric field in the equatorial ionosphere

  16. Citizen Perceptions of E-Government in the Kurdistan Region of Iraq

    Directory of Open Access Journals (Sweden)

    Khosro Mohammad Ahmed

    2015-11-01

    Full Text Available Despite increasing investment by governments globally, citizens in some countries are less willing to engage with e-government innovations. While previous studies have examined what might encourage citizens to adopt e-government services more broadly, further research is required to understand those factors that impede or enable e government adoption in countries that have, or are in the process of, transitioning to democratic self-rule. This study is the first to investigate citizen attitudes to e-government adoption in the Kurdistan Region of Iraq and thus provides insight into the factors affecting the adoption of e-government within an emerging democratic state. This study also distinguishes between two types of e-government services; informational and transactional. Thus a research model with two elements is developed and tested; one for intention to use informational e government and one for intention to use transactional e-government. Data were collected through a survey administered to university students and non-academic employees in Arbil the capital city of Kurdistan, and analysed using structural equation modelling. Perceived usefulness, social influence, trust in government and perceived risk were found to be significantly and directly associated with the intention to use both kinds of e-government services. However perceptions of ease of use, information quality and trust in the Internet were not significant.

  17. Vertical and longitudinal electron density structures of equatorial E- and F-regions

    Directory of Open Access Journals (Sweden)

    P. S. Brahmanandam

    2011-01-01

    Full Text Available From global soundings of ionospheric electron density made with FORMOSAT 3/COSMIC satellites for September 2006–August 2009, day-night variations in vertical and longitudinal structures of the electron densities in equatorial E- and F-regions for different seasons are investigated for the first time. The results reveal that the wavenumber-3 and wavenumber-4 patterns dominated the nighttime (22:00–04:00 LT F-region longitudinal structures in solstice and in equinox seasons, respectively. In daytime (08:00–18:00 LT F-region, the wavenumber-4 patterns governed the longitudinal structures in the September equinox and December solstice, and wavenumber-3 in March equinox and June solstice respectively. A comparison of the daytime and nighttime longitudinal electron density structures indicates that they are approximately 180° out of phase with each other. It is believed that this out of phase relation is very likely the result of the opposite phase relation between daytime and nighttime nonmigrating diurnal tidal winds that modulate background E-region dynamo electric field at different places, leading to the day-night change in the locations of the equatorial plasma fountains that are responsible for the formation of the F-region longitudinal structures. Further, a good consistency between the locations of the density structures in the same seasons of the different years for both daytime and nighttime epochs has been noticed indicating that the source mechanism for these structures could be the same.

  18. Long-term trends in the ionospheric E and F1 regions

    Directory of Open Access Journals (Sweden)

    J. Bremer

    2008-05-01

    Full Text Available Ground based ionosonde measurements are the most essential source of information about long-term variations in the ionospheric E and F1 regions. Data of such observations have been derived at many different ionospheric stations all over the world some for more than 50 years. The standard parameters foE, h'E, and foF1 are used for trend analyses in this paper. Two main problems have to be considered in these analyses. Firstly, the data series have to be homogeneous, i.e. the observations should not be disturbed by artificial steps due to technical reasons or changes in the evaluation algorithm. Secondly, the strong solar and geomagnetic influences upon the ionospheric data have carefully to be removed by an appropriate regression analysis. Otherwise the small trends in the different ionospheric parameters cannot be detected.

    The trends derived at individual stations differ markedly, however their dependence on geographic or geomagnetic latitude is only small. Nevertheless, the mean global trends estimated from the trends at the different stations show some general behaviour (positive trends in foE and foF1, negative trend in h'E which can at least qualitatively be explained by an increasing atmospheric greenhouse effect (increase of CO2 content and other greenhouse gases and decreasing ozone values. The positive foE trend is also in qualitative agreement with rocket mass spectrometer observations of ion densities in the E region. First indications could be found that the changing ozone trend at mid-latitudes (before about 1979, between 1979 until 1995, and after about 1995 modifies the estimated mean foE trend.

  19. More evidence for a planetary wave link with midlatitude E region coherent backscatter and sporadic E layers

    Directory of Open Access Journals (Sweden)

    K. Schlegel

    Full Text Available Measurements of midlatitude E region coherent backscatter obtained during four summers with SESCAT, a 50 MHz Doppler system operating in Crete, Greece, and concurrent ionosonde recordings from the same ionospheric volume obtained with a CADI for one of these summers, are used to analyse the long-term variability in echo and Es occurrence. Echo and Es layer occurrences, computed in percent of time over a 12-h nighttime interval, take the form of time sequences. Linear power spectrum analysis shows that there are dominant spectral peaks in the range of 2–9 days, the most commonly observed periods appearing in two preferential bands, of 2–3 days and 4–7 days. No connection with geomagnetic activity was found. The characteristics of these periodicities compare well with similar properties of planetary waves, which suggests the possibility that planetary waves are responsible for the observed long-term periodicities. These findings indicate also a likely close relation between planetary wave (PW activity and the well known but not well understood seasonal Es dependence. To test the PW postulation, we used simultaneous neutral wind data from the mesopause region around 95 km, measured from Collm, Germany. Direct comparison of the long-term periodicities in echo and Es layer occurrence with those in the neutral wind show some reasonable agreement. This new evidence, although not fully conclusive, is the first direct indication in favour of a planetary wave role on the unstable midlatitude E region ionosphere. Our results suggest that planetary waves observation is a viable option and a new element into the physics of midlatitude Es layers that needs to be considered and investigated.Key words: Ionosphere (ionosphere irregularities; mid-latitude ionosphere – Meteorology and atmospheric dynamics (waves and tides

  20. Propagation and dispersion of electrostatic waves in the ionospheric E region

    Directory of Open Access Journals (Sweden)

    K. Iranpour

    Full Text Available Low-frequency electrostatic fluctuations in the ionospheric E region were detected by instruments on the ROSE rockets. The phase velocity and dispersion of plasma waves in the ionospheric E region are determined by band-pass filtering and cross-correlating data of the electric-field fluctuations detected by the probes on the ROSE F4 rocket. The results were confirmed by a different method of analysis of the same data. The results show that the waves propagate in the Hall-current direction with a velocity somewhat below the ion sound speed obtained for ionospheric conditions during the flight. It is also found that the waves are dispersive, with the longest wavelengths propagating with the lowest velocity.

  1. Propagation and dispersion of electrostatic waves in the ionospheric E region

    Directory of Open Access Journals (Sweden)

    K. Iranpour

    1997-07-01

    Full Text Available Low-frequency electrostatic fluctuations in the ionospheric E region were detected by instruments on the ROSE rockets. The phase velocity and dispersion of plasma waves in the ionospheric E region are determined by band-pass filtering and cross-correlating data of the electric-field fluctuations detected by the probes on the ROSE F4 rocket. The results were confirmed by a different method of analysis of the same data. The results show that the waves propagate in the Hall-current direction with a velocity somewhat below the ion sound speed obtained for ionospheric conditions during the flight. It is also found that the waves are dispersive, with the longest wavelengths propagating with the lowest velocity.

  2. 30 MHz radar observations of artificial E region field-aligned plasma irregularities

    Directory of Open Access Journals (Sweden)

    D. L. Hysell

    2008-02-01

    Full Text Available Artificial E region field aligned irregularities (FAIs have been observed during heating experiments at the HAARP facility using a new 30 MHz coherent scatter radar imager deployed near Homer, Alaska. Irregularities were observed during brief experiments on three quiet days in July and August, 2007, when the daytime E region critical frequency was close to 3 MHz. Irregularities were consistently generated and detected during experiments with O-mode HF pumping on zenith with a 1-min on, 1-min off CW modulation. The scattering cross sections, rise, and fall times of the echoes were observed as well as their spectral properties. Results were found to be mainly in agreement with observations from other mid- and high-latitude sites with some discrepancies. Radar images of the irregularity-filled volume on one case exhibited clear variations in backscatter power and Doppler shift across the volume. The images furthermore show the emergence of a small irregularity-filled region to the south southwest of the main region in the approximate direction of magnetic zenith.

  3. Lipid fluidity at different regions in LDL and HDL of β-thalassemia/Hb E patients

    International Nuclear Information System (INIS)

    Morales, Noppawan Phumala; Charlermchoung, Chalermkhwan; Luechapudiporn, Rataya; Yamanont, Paveena; Fucharoen, Suthat; Chantharaksri, Udom

    2006-01-01

    Atherosclerosis-related vascular complications in β-thalassemia/hemoglobin E (β-thal/Hb E) patients may result from iron induced oxidation of lipoproteins. To identify the specific site of oxidative damage, changes in lipid fluidity at different regions in LDL and HDL particle were investigated using two fluorescence probes and two ESR spin probes. The magnitude of increased lipid fluidity in thalassemic lipoproteins was dependent on the location of the probes. In hydrophobic region, the rotational correlation times for 16-doxyl stearic acid and DPH anisotropy were markedly changed in LDL and HDL of the patients. In the surface region, there was only a slight change in the order parameter (S) for 5-doxyl stearic acid and TMA-DPH anisotropy. Lipid fluidity at the core of LDL and HDL showed good correlation with oxidative stress markers, the ratio of CL/CO, and the level of α-tocopherol, suggesting that hydrophobic region of thalassemic lipoprotein was a target site for oxidative damage

  4. First E- and D-region incoherent scatter spectra observed over Jicamarca

    Directory of Open Access Journals (Sweden)

    J. L. Chau

    2006-07-01

    Full Text Available We present here the first Jicamarca observations of incoherent scatter radar (ISR spectra detected from E- and D-region altitudes. In the past such observations have not been possible at Jicamarca due a combined effect of strong equatorial electrojet (EEJ clutter and hardware limitations in the receiving system. The observations presented here were made during weak EEJ conditions (i.e., almost zero zonal electric field using an improved digital receiving system with a wide dynamic range and a high data throughput. The observed ISR spectra from E- and D-region altitudes are, as expected, narrow and get even narrower with decreasing altitude due to increasing ion-neutral collision frequencies. Therefore, it was possible to obtain accurate spectral measurements using a pulse-to-pulse data analysis. At lower altitudes in the D-region where signal correlation times are relatively long we used coherent integration to improve the signal-to-noise ratio of the collected data samples. The spectral estimates were fitted using a standard incoherent scatter (IS spectral model between 87 and 120 km, and a Lorentzian function below 110 km. Our preliminary estimates of temperature and ion-neutral collisions frequencies above 87 km are in good agreement with the MSISE-90 model. Below 87 km, the measured spectral widths are larger than expected, causing an overestimation of the temperatures, most likely due to spectral distortions caused by atmospheric turbulence.

  5. An experimental study of the ion chemistry and thermal balance in the E- and F-regions above Wallops Island

    Science.gov (United States)

    Brace, L. H.; Mayr, H. G.; Pharo, M. W., III; Scott, L. R.; Taylor, H. A., Jr.

    1971-01-01

    E and F region positive ion composition, electron concentration and thermal balance vertical profile, discussing ionizing radiation spectrum, plasma cooling, primary chemical reaction rates and ionospheric formation

  6. eHealth for Remote Regions: Findings from Central Asia Health Systems Strengthening Project.

    Science.gov (United States)

    Sajwani, Afroz; Qureshi, Kiran; Shaikh, Tehniat; Sayani, Saleem

    2015-01-01

    Isolated communities in remote regions of Afghanistan, Kyrgyz Republic, Pakistan and Tajikistan lack access to high-quality, low-cost health care services, forcing them to travel to distant parts of the country, bearing an unnecessary financial burden. The eHealth Programme under Central Asia Health Systems Strengthening (CAHSS) Project, a joint initiative between the Aga Khan Foundation, Canada and the Government of Canada, was initiated in 2013 with the aim to utilize Information and Communication Technologies to link health care institutions and providers with rural communities to provide comprehensive and coordinated care, helping minimize the barriers of distance and time. Under the CAHSS Project, access to low-cost, quality health care is provided through a regional hub and spoke teleconsultation network of government and non-government health facilities. In addition, capacity building initiatives are offered to health professionals. By 2017, the network is expected to connect seven Tier 1 tertiary care facilities with 14 Tier 2 secondary care facilities for teleconsultation and eLearning. From April 2013 to September 2014, 6140 teleconsultations have been provided across the project sites. Additionally, 52 new eLearning sessions have been developed and 2020 staff members have benefitted from eLearning sessions. Ethics and patient rights are respected during project implementation.

  7. Partial wave analysis of KKPI system in D and E/IOTA region

    International Nuclear Information System (INIS)

    Chung, S.U.; Fernow, R.; Kirk, H.

    1985-01-01

    A partial wave analysis and a Dalitz plot analysis of high-statistics data from reaction π - p → K + K/sub S/π - n at 8.0 GeV/c show that the D(1285) is a J/sup PG/ = 1 ++ state and the E(1420) a J/sup PG/ = 0 -+ state both with a substantial deltaπ decay mode. The 1 ++ K*anti K wave exhibits a rapid rise near threshold but no evidence of a resonance in the E region. The assignment of J/sup PG/ = O -+ to the E is confirmed from a Dalitz-plot analysis of the reaction pp → K + K/sub S/π - X 0 . 11 refs., 5 figs

  8. Bem-estar social, mercado de trabalho e o desequilíbrio regional brasileiro

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Manso

    2010-06-01

    Full Text Available Este trabalho contribui para a literatura empírica sobre o desequilíbrio regional brasileiro, ao analisar, no período pós-Plano Real, o desempenho econômico de cada região do País em termos do crescimento pró-pobre - crescimento econômico acompanhado de redução na desigualdade - e do bem-estar social. Para tanto, utiliza-se metodologia presente em Kakwani, Neri e Son (2006 para avaliar o comportamento do bem-estar social a partir das distribuições da renda familiar e da renda salarial em cada região do País. Investiga-se também a contribuição de indicadores do mercado de trabalho nas performances das regiões. De uma forma geral, os resultados apontam que os maiores impactos na renda dos trabalhos e no bem-estar social deveram-se à taxa de participação de trabalhadores por família e, principalmente, aos ganhos de produtividade dos trabalhadores a partir de 2003, que, por sua vez, foram motivados principalmente pelos acréscimos nos retornos médios provenientes da educação das pessoas ocupadas. Porém, esses ganhos não foram suficientes para o estabelecimento de um padrão de crescimento mais intensamente pró-pobre no Norte e no Nordeste, o que poderia ter contribuído para uma maior aproximação em termos de renda e bem-estar social destas regiões em relação às outras do País.This paper contributes to the empirical literature about the Brazilian regional disequilibrium, once it examines, in the post-Real Plan period, the economic performance of each region of the country in terms of pro-poor growth - growth with reduced inequality - and of the social welfare. To this, it is used the methodology present in Kakwani, Neri and Son (2006 to evaluate the behavior of social welfare from the distributions of familiar income and wage income in each region. Furthermore, it is investigated the contribution of labor market indicators in the performance of regions. In general, the results indicate that the greatest impacts on

  9. A first comparison of irregularity and ion drift velocity measurements in the E-region

    Directory of Open Access Journals (Sweden)

    R. A. Makarevich

    2006-09-01

    Full Text Available E-region irregularity velocity measurements at large flow angles with the STARE Finland coherent VHF radar are considered in context of the ion and electron velocity data provided by the EISCAT tristatic radar system, CUTLASS Finland coherent HF radar, and IMAGE fluxgate magnetometers. The data have been collected during a special experiment on 27 March 2004 during which EISCAT was scanning between several E- and one F-region altitudes along the magnetic field line. Within the E-region, the EISCAT measurements at two altitudes of 110 and 115 km are considered while the electron velocity is inferred from the EISCAT ion velocity measurements at 278 km. The line-of-sight (l-o-s VHF velocity measured by STARE VHF los is compared to the ion and electron velocity components (Vi0 comp and Ve0 comp along the STARE l-o-s direction. The comparison with Ve0 comp for the entire event shows that the measurements exhibit large scatter and small positive correlation. The correlation with Ve0 comp was substantial in the first half of the interval under study when Ve0 comp was larger in magnitude. The comparison with Vi0 comp at 110 and 115 km shows a considerable positive correlation, with VHF velocity being typically larger (smaller in magnitude than Vi0 comp at 110 km (115 km so that VVHF los appears to be bounded by the ion velocity components at two altitudes. It is also demonstrated that the difference between VVHF los and Vi0 comp at 110 km can be treated, in the first approximation, as a linear function of the effective backscatter height heff also counted from 110 km; heff varies in the range 108–114 km due to the altitude integration effects in the scattering cross-section. Our results are consistent with the notion that VHF

  10. A nova configuração regional brasileira e sua geografia econômica

    Directory of Open Access Journals (Sweden)

    Mauro Borges Lemos

    2003-12-01

    Full Text Available O objetivo deste trabalho é identificar a nova configuração regional brasileira, procurando delimitar seus pólos econômicos e suas áreas de influência, como base para uma proposta de nova regionalização para o Brasil. Para isto, é construída uma metodologia específica, baseada na aplicação do Modelo Gravitacional, comumente usado em estudos espaciais, por meio do Sistema de Informações Geográficas - SIG. Este procedimento possibilita a identificação das regiões-pólos e suas áreas de influência, com base no potencial de interação econômica entre as unidades espaciais e na correspondente hierarquia de poder de atração econômica no espaço. As microrregiões geográficas (MRGs do IBGE constituem a unidade espacial básica deste estudo, que se baseia nos microdados do Censo Demográfico de 1991. A base cartográfica digital foi a Malha Municipal Digital do Brasil, convertida para o Mapinfo. A regionalização final incorpora, em seus resultados, uma qualificação da fricção espacial.The aim of this paper is to identify the new regional pattern of the Brazilian economy by defining its economic poles and their areas of polarization, which will provide an economic regionalization for Brazil. The methodological tools to assign this objective will be an adapted version of the gravitational model using the Geographic Information System - GIS. This procedure will allow the identification of the influence areas for each regional pole, based on the potential interaction among the spatial units and their hierarchy in terms of economic power of attraction. The microregion of the Brazilian Statistics Bureau (IBGE will be the spatial unit of this study, which will rely on microdata of the 1991 Demographic Census. The digital cartographic base is the Brazilian Municipal Digital Network converted into the MapInfo. The results will provide a hierarchical spatial structure of macro regions, mesoregions, microregions, and

  11. A Statistical Study of Eiscat Electron and Ion Temperature Measurements In The E-region

    Science.gov (United States)

    Hussey, G.; Haldoupis, C.; Schlegel, K.; Bösinger, T.

    Motivated by the large EISCAT data base, which covers over 15 years of common programme operation, and previous statistical work with EISCAT data (e.g., C. Hal- doupis, K. Schlegel, and G. Hussey, Auroral E-region electron density gradients mea- sured with EISCAT, Ann. Geopshysicae, 18, 1172-1181, 2000), a detailed statistical analysis of electron and ion EISCAT temperature measurements has been undertaken. This study was specifically concerned with the statistical dependence of heating events with other ambient parameters such as the electric field and electron density. The re- sults showed previously reported dependences such as the electron temperature being directly correlated with the ambient electric field and inversely related to the electron density. However, these correlations were found to be also dependent upon altitude. There was also evidence of the so called "Schlegel effect" (K. Schlegel, Reduced effective recombination coefficient in the disturbed polar E-region, J. Atmos. Terr. Phys., 44, 183-185, 1982); that is, the heated electron gas leads to increases in elec- tron density through a reduction in the recombination rate. This paper will present the statistical heating results and attempt to offer physical explanations and interpretations of the findings.

  12. Radar observations of artificial E-region field-aligned irregularities

    Directory of Open Access Journals (Sweden)

    E. Nossa

    2009-07-01

    Full Text Available Artificial E region field aligned plasma density irregularities (FAIs were generated using HAARP in four different experimental modes and observed with a coherent scatter radar imager located 450 km to the southwest where it could detect field-aligned backscatter. The experiments were conducted in July of 2008, during the Polar Aeronomy and Radio Science Summer School (PARS, during quiet conditions in the daytime when the E layer was dense and absorption was modest. The echoes observed during zenith and magnetic zenith heating experiments were deflected from their nominally anticipated horizontal positions toward the midpoint position. The occurrence of hysteresis when heating with amplitude modulated pulses implied the development of the resonance instability, although the threshold for the onset of instability appeared to be higher than what has been predicted theoretically. Heating experiments involving pump frequencies slightly above and below the second electron gyroharmonic frequency produced no significant differences in the observed echoes. Finally, heating with a pump frequency slightly above the E region critical frequency appears to have produced FAIs at two distinct altitudes where the upper-hybrid resonance condition could be satisfied.

  13. Possible interaction between thermal electrons and vibrationally excited N2 in the lower E-region

    Directory of Open Access Journals (Sweden)

    K.-I. Oyama

    2011-03-01

    Full Text Available As one of the tasks to find the energy source(s of thermal electrons, which elevate(s electron temperature higher than neutral temperature in the lower ionosphere E-region, energy distribution function of thermal electron was measured with a sounding rocket at the heights of 93–131 km by the applying second harmonic method. The energy distribution function showed a clear hump at the energy of ~0.4 eV. In order to find the reason of the hump, we conducted laboratory experiment. We studied difference of the energy distribution functions of electrons in thermal energy range, which were measured with and without EUV radiation to plasma of N2/Ar and N2/O2 gas mixture respectively. For N2/Ar gas mixture plasma, the hump is not clearly identified in the energy distribution of thermal electrons. On the other hand for N2/O2 gas mixture, which contains vibrationally excited N2, a clear hump is found when irradiated by EUV. The laboratory experiment seems to suggest that the hump is produced as a result of interaction between vibrationally excited N2 and thermal electrons, and this interaction is the most probable heating source for the electrons of thermal energy range in the lower E-region. It is also suggested that energy distribution of the electrons in high energy part may not be Maxwellian, and DC probe measures the electrons which are non Maxwellian, and therefore "electron temperature" is calculated higher.

  14. Microeconomia Dinâmica e Desenvolvimento Regional à Luz da Teoria Evolucionária

    Directory of Open Access Journals (Sweden)

    Alexandre Magno de Melo Faria

    2011-05-01

    Full Text Available O presente artigo procura lançar luzes sobre a discussão da Teoria Evolucionária, teoria esta que visa encontrar os determinantes do desenvolvimento econômico e social das nações. Discute também as estruturas de mercado em ambientes competitivos e suas relações com a geração de tecnologia. A partir dos fatos estilizados, esta matriz teórica explicita que as firmas são as unidades básicas de acumulação de capital, complexas e especializadas, que estão constantemente sendo selecionadas em função de seu comportamento e sua tecnologia. Conclui-se o artigo afirmando que a evolução tecnológica é a principal variável no processo seletivo das firmas e que, em última instância, será essa que irá determinar o grau de desenvolvimento regional.

  15. E-Cigarettes: Implications for Health Promotion in the Asian Pacific Region.

    Science.gov (United States)

    Jancey, Jonine; Maycock, Bruce; McCausland, Kahlia; Howat, Peter

    2018-03-01

    Since their introduction to the United States in 2007, electronic cigarettes (e-cigarettes) use has grown exponentially. This rapid growth in e-cigarette use has been heralded by some as a potential important public health measure that could ultimately replace tobacco cigarettes, while others recommend a cautionary approach until there is clear evidence they will not become "new tobacco" bringing a possible myriad of other problems. E-cigarettes may have real benefits, however they do expose users and those nearby to organic compounds, solvents and particulate matter, with there being limited data relating to their health impact. It is unclear as to whether this relatively new device has the potential to exacerbate nicotine addictions, or play a part in reducing harm and smoking cessation. The fundamental requirement of public health practice is to do no harm and from the inconclusive evidence we have to date on e-cigarettes, it appears a cautious approach is warranted. This commentary reviews evidence that supports a cautious approach to e-cigarette availability in Australia and the Asian Pacific region.

  16. Crescimento e integração regional no Sudeste Asiático

    OpenAIRE

    Vendeirinho, Sónia Patrícia da Silva

    2014-01-01

    Mestrado em Desenvolvimento e Cooperação Internacional Esta dissertação tem como principal objectivo analisar a seguinte questão: "A Integração Regional (Triângulos de Crescimento) é um factor para o Crescimento Económico no Sudeste Asiático?". Para analisar esta hipótese apresenta-se um modelo de crescimento que inclui a variável Integração Regional. O modelo é testado a partir de um Panel Data dinâmico, usando os dados dos nove países escolhidos para o estudo - Austrália, Cambodja, Indon...

  17. Significance of scatter radar studies of E and F region irregularities at high latitudes

    International Nuclear Information System (INIS)

    Greenwald, R.A.

    1983-01-01

    This chapter considers the mechanisms by which electron density irregularities may be generated in the high latitude ionosphere and the techniques through which they are observed with ground base radars. The capabilities of radars used for studying these irregularities are compared with the capabilities of radars used for incoherent scatter measurements. The use of irregularity scatter techniques for dynamic studies of larger scale structured phenomena is discussed. Topics considered include E-region irregularities, observations with auroral radars, plasma drifts associated with a westward travelling surge, and ionospheric plasma motions associated with resonant waves. It is shown why high latitude F-region irregularity studies must be made in the HF frequency band (3-30 MHz). The joint use of the European Incoherent Scatter Association (EISCAT), STARE and SAFARI facilities is examined, and it is concluded that the various techniques will enhance each other and provide a better understanding of the various processes being studied

  18. E-region decameter-scale plasma waves observed by the dual TIGER HF radars

    Directory of Open Access Journals (Sweden)

    B. A. Carter

    2009-01-01

    Full Text Available The dual Tasman International Geospace Environment Radar (TIGER HF radars regularly observe E-region echoes at sub-auroral magnetic latitudes 58°–60° S including during geomagnetic storms. We present a statistical analysis of E-region backscatter observed in a period of ~2 years (late 2004–2006 by the TIGER Bruny Island and Unwin HF radars, with particular emphasis on storm-time backscatter. It is found that the HF echoes normally form a 300-km-wide band at ranges 225–540 km. In the evening sector during geomagnetic storms, however, the HF echoes form a curved band joining to the F-region band at ~700 km. The curved band lies close to the locations where the geometric aspect angle is zero, implying little to no refraction during geomagnetic storms, which is an opposite result to what has been reported in the past. The echo occurrence, Doppler velocity, and spectral width of the HF echoes are examined in order to determine whether new HF echo types are observed at sub-auroral latitudes, particularly during geomagnetic storms. The datasets of both TIGER radars are found to be dominated by low-velocity echoes. A separate population of storm-time echoes is also identified within the datasets of both radars with most of these echoes showing similar characteristics to the low-velocity echo population. The storm-time backscatter observed by the Bruny Island radar, on the other hand, includes near-range echoes (r<405 km that exhibit some characteristics of what has been previously termed the High Aspect angle Irregularity Region (HAIR echoes. We show that these echoes appear to be a storm-time phenomenon and further investigate this population by comparing their Doppler velocity with the simultaneously measured F- and E-region irregularity velocities. It is suggested that the HAIR-like echoes are observed only by HF radars with relatively poor geometric aspect angles when electron density is low and when the electric field is particularly

  19. Auroral E-region diagnosis by means of nonlinearly stabilized plasma waves

    International Nuclear Information System (INIS)

    Primdahl, F.; Bahnsen, A.

    1985-01-01

    Recently published comparative measurements indicate that the phase velocity of low frequency waves in the ionospheric E-region is often lower than the drift speed of the electrons that drive the waves unstable. This finding is in agreement with a rocket experiment that measured plasma waves ''in situ''. These data are reevaluated in the present paper. In order to understand these results, the linear instability theory is modified, following Sudan, to conform with zero growth rate even above threshold. The result is that the waves travel at the ion-acoustic velocity with an amplitude stabilized at a level which is found to agree with our observations

  20. Planetary and tidal wave-type oscillations in the ionospheric sporadic E layers over Tehran region

    Science.gov (United States)

    Karami, K.; Ghader, S.; Bidokhti, A. A.; Joghataei, M.; Neyestani, A.; Mohammadabadi, A.

    2012-04-01

    It is believed that in the lower ionosphere, particularly in the ionospheric sporadic E (Es) layers (90-130 km), the planetary and tidal wave-type oscillations in the ionized component indicate the planetary and tidal waves in the neutral atmosphere. In the present work, the presence of wave-type oscillations, including planetary and tidal waves in the ionospheric sporadic E layers over Tehran region is examined. Data measured by a digital ionosonde at the ionospheric station of the Institute of Geophysics, University of Tehran, from July 2006 to June 2007 are used to investigate seasonal variations of planetary and tidal waves activities. For the purpose of accurate comparison between different seasons, wavelet transform is applied to time series of foEs and h‧Es, namely, the critical frequency and virtual height of Es layers, respectively. The results show that the sporadic E layers over Tehran region are strongly under the influence of upward propagation of waves from below. More specifically, among diverse range of periodicities in the sporadic E layers, we found that diurnal (24 hours) and semidiurnal (12 hours) oscillations in all seasons for both parameters. Moreover, terdiurnal (8 hours) tide-like variation is observed during spring and summer for foEs parameter and summer and winter for h‧Es. Furthermore, the results show that diurnal tidal waves obtain their maximum activities during autumn and winter seasons, and their activities decrease during the late spring and summer. In addition, periods of about 2, 4, 6, 10, 14, and 16 days in our observation verifies the hypothesis of upward propagation of planetary waves from lower atmosphere to the ionosphere. Moreover, planetary waves have their maximum activities during equinox.

  1. Authentication Architecture for Region-Wide e-Health System with Smartcards and a PKI

    Science.gov (United States)

    Zúquete, André; Gomes, Helder; Cunha, João Paulo Silva

    This paper describes the design and implementation of an e-Health authentication architecture using smartcards and a PKI. This architecture was developed to authenticate e-Health Professionals accessing the RTS (Rede Telemática da Saúde), a regional platform for sharing clinical data among a set of affiliated health institutions. The architecture had to accommodate specific RTS requirements, namely the security of Professionals' credentials, the mobility of Professionals, and the scalability to accommodate new health institutions. The adopted solution uses short-lived certificates and cross-certification agreements between RTS and e-Health institutions for authenticating Professionals accessing the RTS. These certificates carry as well the Professional's role at their home institution for role-based authorization. Trust agreements between e-Health institutions and RTS are necessary in order to make the certificates recognized by the RTS. As a proof of concept, a prototype was implemented with Windows technology. The presented authentication architecture is intended to be applied to other medical telematic systems.

  2. Vaccinazione antinfluenzale nella ASL RMF della Regione Lazio: verifica dei risultati e dei costi sostenuti

    Directory of Open Access Journals (Sweden)

    L. Di Marzio

    2003-05-01

    Full Text Available

    Obiettivi: la vaccinazione antinfluenzale nella
    Regione Lazio dalla campagna 1999-2000 viene
    condotta sulla base di un protocollo regionale che,
    per favorire il raggiungimento degli obiettivi stabiliti
    dal Piano Sanitario Nazionale, coinvolge i
    Medici di Medicina Generale (MMG prevedendo
    una remunerazione aggiuntiva in parte fissa (a prestazione, in parte variabile (condizionata dal risultato
    del singolo medico e della ASL.
    Gli autori si propongono una verifica dei risultati raggiunti e dei costi sostenuti dall’ultima campagna eseguita con sole risorse aziendali del 1998-99 a quella del 2002-03.

    Metodi: il protocollo regionale prevede la raccolta
    delle informazioni per ciascun vaccinato presente
    nell’anagrafe informatizzata degli assistiti aziendali
    e ciò consente la valutazione delle coperture vaccinali
    aziendale e per ciascun MMG.
    Parallelamente sono considerati costi dei vaccini
    acquistati e retribuzione aggiuntiva dei MMG.

    Risultati: esaminati gli archivi dal 1998-99 al 2002-
    03, emerge il progressivo coinvolgimento dei MMG fino al recente 97%, l’aumento inequivocabile delle dosi di vaccino somministrate (da 9.406 a 36.692 e del tasso di copertura negli anziani (dal 24,2% al 66%. Invece la percentuale dei vaccini somministrati ai ›65 diminuisce dal 85,47% al 71,77% ed aumenta a favore dei più giovani così da risultare coperture negli ultrasessantacinquenni inferiori alle attese.Con gli anni l’integrazione dell’esperienza del servizio e dei MMG ha favorito un più oculato approvvigionamento
    con diminuzione degli sprechi passando dal 15,56% nel 2000-01 all’attuale 4,45%, ma contestualmente i costi risultano decuplicati (da 90 a 938 milioni di lire per maggior numero di dosi somministrate e costo delle prestazioni dei MMG

  3. Towards an e-Health Cloud Solution for Remote Regions at Bahia-Brazil.

    Science.gov (United States)

    Sarinho, V T; Mota, A O; Silva, E P

    2017-12-19

    This paper presents CloudMedic, an e-Health Cloud solution that manages health care services in remote regions of Bahia-Brazil. For that, six main modules: Clinic, Hospital, Supply, Administrative, Billing and Health Business Intelligence, were developed to control the health flow among health actors at health institutions. They provided database model and procedures for health business rules, a standard gateway for data maintenance between web views and database layer, and a multi-front-end framework based on web views and web commands configurations. These resources were used by 2042 health actors in 261 health posts covering health demands from 118 municipalities at Bahia state. They also managed approximately 2.4 million health service 'orders and approximately 13.5 million health exams for more than 1.3 million registered patients. As a result, a collection of health functionalities available in a cloud infrastructure was successfully developed, deployed and validated in more than 28% of Bahia municipalities. A viable e-Health Cloud solution that, despite municipality limitations in remote regions, decentralized and improved the access to health care services at Bahia state.

  4. The terminal region of the E. coli chromosome localises at the periphery of the nucleoid

    Directory of Open Access Journals (Sweden)

    Stouf Mathieu

    2011-02-01

    Full Text Available Abstract Background Bacterial chromosomes are organised into a compact and dynamic structures termed nucleoids. Cytological studies in model rod-shaped bacteria show that the different regions of the chromosome display distinct and specific sub-cellular positioning and choreographies during the course of the cell cycle. The localisation of chromosome loci along the length of the cell has been described. However, positioning of loci across the width of the cell has not been determined. Results Here, we show that it is possible to assess the mean positioning of chromosomal loci across the width of the cell using two-dimension images from wide-field fluorescence microscopy. Observed apparent distributions of fluorescent-tagged loci of the E. coli chromosome along the cell diameter were compared with simulated distributions calculated using a range of cell width positioning models. Using this method, we detected the migration of chromosome loci towards the cell periphery induced by production of the bacteriophage T4 Ndd protein. In the absence of Ndd production, loci outside the replication terminus were located either randomly along the nucleoid width or towards the cell centre whereas loci inside the replication terminus were located at the periphery of the nucleoid in contrast to other loci. Conclusions Our approach allows to reliably observing the positioning of chromosome loci along the width of E. coli cells. The terminal region of the chromosome is preferentially located at the periphery of the nucleoid consistent with its specific roles in chromosome organisation and dynamics.

  5. Wind effect on the motion of medium-scale travelling ionospheric disturbances in the E region of the ionosphere

    International Nuclear Information System (INIS)

    Kikvilashvili, G.B.; Sharadze, Z.S.; Mosashvili, N.V.

    1988-01-01

    Madium-scale travelling ionospheric disturbances (MSTID) in the ionosphere E region in Tbilisi area are investigated by means of spectral analysis of f 0 E s and f b E s variations, synchronously recorded in the three scattered points. The winds at the E s layers formation heights were measured simultaneously by D1 method in one of these points. It is established, that the MSTID motion direction in summer-time E region is controlled by the background thermospheric winds: disturbances mostly more across and against the wind. Tidal winds make the main contribution into the MSTID rate day variations

  6. Deletion mutants of region E1 a of AD12 E1 plasmids: Effect on oncogenic transformation

    NARCIS (Netherlands)

    Bos, J.L.; Jochemsen, A.G.; Bernards, R.A.; Schrier, P.I.; Ormondt, H. van; Eb, A.J. van der

    1983-01-01

    Plasmids containing the El region of Ad12 DNA can transform certain rodent cells into oncogenic cells. To study the role of the Ela subregion in the process of oncogenic transformation, Ad12 region El mutants carrying deletions in the Ela region were constructed. Deletion mutants pR7 and pR8 affect

  7. Neutralizing activities of caprine antibodies towards conserved regions of the HCV envelope glycoprotein E2

    Directory of Open Access Journals (Sweden)

    El-Shenawy Reem

    2011-08-01

    Full Text Available Abstract Anti HCV vaccine is not currently available and the present antiviral therapies fail to cure approximately half of the treated HCV patients. This study was designed to assess the immunogenic properties of genetically conserved peptides derived from the C-terminal region of HVR-1 and test their neutralizing activities in a step towards developing therapeutic and/or prophylactic immunogens against HCV infection. Antibodies were generated by vaccination of goats with synthetic peptides derived from HCV E2. Viral neutralizing capacity of the generated anti E2 antibodies was tested using in vitro assays. Goats immunized with E2 synthetic peptides termed p412 [a.a 412-419], p430 [a.a 430-447] and p517 [a.a 517-531] generated high titers of antibody responses 2 to 4.5 fold higher than comparable titers of antibodies to the same epitopes in chronic HCV patients. In post infection experiments of native HCV into cultured Huh7.5 cells anti p412 and anti p 517 were proven to be neutralizing to HCV genotype 4a from patients' sera (87.5% and 75% respectively. On the contrary anti p430 exhibited weak viral neutralization capacity on the same samples (31.25%. Furthermore Ab mixes containing anti p430 exhibited reduced viral neutralization properties. From these experiments one could predict that neutralization by Abs towards different E2-epitopes varies considerably and success in the enrichment of neutralization epitope-specific antibodies may be accompanied by favorable results in combating HCV infection. Also, E2 conserved peptides p517 and p412 represent potential components of a candidate peptide vaccine against HCV infection.

  8. Observation of electron biteout regions below sporadic E layers at polar latitudes

    Directory of Open Access Journals (Sweden)

    G. A. Lehmacher

    2015-03-01

    Full Text Available The descent of a narrow sporadic E layer near 95 km altitude over Poker Flat Research Range in Alaska was observed with electron probes on two consecutive sounding rockets and with incoherent scatter radar during a 2 h period near magnetic midnight. A series of four trimethyl aluminum chemical releases demonstrated that the Es layer remained just slightly above the zonal wind node, which was slowly descending due to propagating long-period gravity waves. The location of the layer is consistent with the equilibrium position due to combined action of the wind shear and electric fields. Although the horizontal electric field could not be measured directly, we estimate that it was ~ 2 mV m−1 southward, consistent with modeling the vertical ion drift, and compatible with extremely quiet conditions. Both electron probes observed deep biteout regions just below the Es enhancements, which also descended with the sporadic layers. We discuss several possibilities for the cause of these depletions; one possibility is the presence of negatively charged, nanometer-sized mesospheric smoke particles. Such particles have recently been detected in the upper mesosphere, but not yet in immediate connection with sporadic E. Our observations of electron depletions suggest a new process associated with sporadic E.

  9. Simulation of D and E region high-power microwave heating with HF ionospheric modification experiments

    International Nuclear Information System (INIS)

    Meltz, G.; Rush, C.M.; Violette, E.J.

    1981-01-01

    The microwave power beam from a Solar Power Satellite (SPS) is sufficiently intense to cause large changes in the properties of the lower ionosphere by ohmic heating of the plasma. Power is absorbed from the beam at a rate that is proportional to the ratio of the flux s and the square of an effective frequency f/sub e/. Throughout most of the lower ionosphere f/sub e/ = f -+ f/sub L/, where f is the wave frequency and f/sub L is a reduced electron gyrofrequency. It follows that SPS equivalent heating can be simulated at much lower power fluxes with HF radio waves. A detailed examination of the frequency scaling, based on fluid and kinetic theory estimates of the change in electron temperature and density, shows that the high-power HF facility at Platteville, CO, can simulate or exceed the ohmic effects of the SPS beam up to 90 km. This paper describes the results of a series of 5.2 and 9.9 MHz underdense heating experiments undertaken to study the effect of high-power microwaves on the lower ionosphere. A pulsed ionosonde probe, located nearly below the most intense portion of the high-power beam, was used to observe the changes in the D and lower E region. Both phase and amplitude measurements were recorded during CW and intermittent heating

  10. Roles of the conserved cytoplasmic region and non-conserved carboxy-terminal region of SecE in Escherichia coli protein translocase.

    Science.gov (United States)

    Kontinen, V P; Yamanaka, M; Nishiyama, K; Tokuda, H

    1996-06-01

    SecE, an essential membrane component of the Escherichia coli protein translocase, consists of 127 amino acid residues. Only a part of the second putative cytoplasmic region comprising some 13 residues is essential for the SecE function as long as the proper topological arrangement is retained. The Trp84 and Pro85 residues of this region are conserved in all eubacterial SecE homologues. The conservation of positively charged residues corresponding to Arg80 and Lys81 is also substantial. We deleted or replaced these residues to assess their roles in the SecE function. Deletion of the Arg80-Lys81 dipeptide did not abolish the SecE function whereas that of Trp84 or Pro85 caused a loss of the function. Strikingly, however, replacement of Pro85 with either Gly, Ser, or Ala, and that of Trp84 with Lys did not abolish the SecE function. These results indicate that the strong conservation of these residues does not reflect their obligatory requirement for the SecE function. A chimeric SecE possessing the cytoplasmic region of the E. coli SecE and the following region of the Bacillus subtilis SecE was able to form the translocation machinery together with SecA, SecY, and SecG. Although a Leu to Arg mutation at position 108 has been thought to cause a loss of signal recognition fidelity and thereby suppress a signal sequence defect, the same mutation at position 111 caused a complete loss of the function. The levels of SecY and SecG in the secEcsE501 mutant, which expresses SecE at a decreased level and is sensitive to low temperature, increased upon the expression of functional SecE derivatives, irrespective of the site of mutation, suggesting that the levels of SecY and SecG are co-operatively determined by the level of functional, but not non-functional, SecE. Based on these results, the SecE function in the translocase is discussed.

  11. Il SIT della Regione Puglia, uno strumento a beneficio dei comuni e degli enti locali della Regione

    Directory of Open Access Journals (Sweden)

    Valeria De Vecchi

    2009-03-01

    Full Text Available Puglia region's GIS: a tool in behalf of local public organizationsInnovaPuglia, together with ESRI Italia and Sinergis as technological partners, set up a Geographic Information Systemfor the italian Puglia region. It will help this public organization to better plan and manage the land and the environment of that part of Italy. The possibility to share land informations is one of the mail features of the system: this will be extremely helpful for the government activities and to fullfill land knowledge with precise and homogeneous data.

  12. Retornos da educação e o desequilíbrio regional no Brasil

    Directory of Open Access Journals (Sweden)

    Carlos Alberto Manso

    2010-06-01

    Full Text Available O problema do desequilíbrio regional brasileiro normalmente tem sido tratado na literatura nacional a partir de investigações que utilizam a renda e/ou PIB per capita como variáveis de análise. Para sociedades com baixos níveis de desigualdade, esse procedimento é uma boa representação do bem-estar social. Entretanto, para economias com elevados níveis de pobreza e desigualdade, a utilização da renda ou PIB pode não ser apropriada. Nesse sentido, esse artigo discute se a aproximação da renda per capita existente entre o Nordeste e o Sudeste brasileiro também vem ocorrendo em termos de bem-estar social. Para esse objetivo, duas medidas de bem-estar social são utilizadas: Sen (1977 e Kakwani e Son (2008. Os resultados apontam que, assim como ocorre com a renda per capita, também está havendo aproximação de bemestar considerando a medida de Sen. Entretanto, quando se leva em conta o movimento da renda dos mais pobres, presente no segundo índice, constata-se um afastamento entre as duas regiões. As análises são feitas para o período de 1995 a 2007. Por fim, identificou-se que foram os ganhos de produtividade dos trabalhadores pertencentes a famílias pobres no Sudeste os principais responsáveis por esse distanciamento.The problem of Brazilian regional disequilibrium has usually been treated in the national literature from investigations using income and/or GDP percapita as a variable of analysis. For communities with low levels of inequality, this procedure is a good representation of the social welfare. However, for economies with high levels of poverty and inequality, the use of income or GDP cannot be appropriate. Accordingly, this article discusses if the approximation of per capita income between the Northeast and Southeast Brazil has also occurred in terms of social welfare. To this, two measures of social welfare are used: Sen (1977 and Kakwani e Son (2008. The results suggest as occurs with per capita income, there

  13. Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization.

    Science.gov (United States)

    Ozawa, Akihiko; Brunori, Gloria; Mercatelli, Daniela; Wu, Jinhua; Cippitelli, Andrea; Zou, Bende; Xie, Xinmin Simon; Williams, Melissa; Zaveri, Nurulain T; Low, Sarah; Scherrer, Grégory; Kieffer, Brigitte L; Toll, Lawrence

    2015-08-19

    The nociceptin/orphanin FQ (NOP) receptor, the fourth member of the opioid receptor family, is involved in many processes common to the opioid receptors including pain and drug abuse. To better characterize receptor location and trafficking, knock-in mice were created by inserting the gene encoding enhanced green fluorescent protein (eGFP) into the NOP receptor gene (Oprl1) and producing mice expressing a functional NOP-eGFP C-terminal fusion in place of the native NOP receptor. The NOP-eGFP receptor was present in brain of homozygous knock-in animals in concentrations somewhat higher than in wild-type mice and was functional when tested for stimulation of [(35)S]GTPγS binding in vitro and in patch-clamp electrophysiology in dorsal root ganglia (DRG) neurons and hippocampal slices. Inhibition of morphine analgesia was equivalent when tested in knock-in and wild-type mice. Imaging revealed detailed neuroanatomy in brain, spinal cord, and DRG and was generally consistent with in vitro autoradiographic imaging of receptor location. Multicolor immunohistochemistry identified cells coexpressing various spinal cord and DRG cellular markers, as well as coexpression with μ-opioid receptors in DRG and brain regions. Both in tissue slices and primary cultures, the NOP-eGFP receptors appear throughout the cell body and in processes. These knock-in mice have NOP receptors that function both in vitro and in vivo and appear to be an exceptional tool to study receptor neuroanatomy and correlate with NOP receptor function. The NOP receptor, the fourth member of the opioid receptor family, is involved in pain, drug abuse, and a number of other CNS processes. The regional and cellular distribution has been difficult to determine due to lack of validated antibodies for immunohistochemical analysis. To provide a new tool for the investigation of receptor localization, we have produced knock-in mice with a fluorescent-tagged NOP receptor in place of the native NOP receptor. These

  14. Measuring the usability of e-banking in Special Region of Yogyakarta

    Directory of Open Access Journals (Sweden)

    Hadyanawati Anindyya Agripina

    2018-01-01

    Full Text Available Online shopping is become an option because customers do not need to go to the store. Internet banking is a bank facility to help customers in common. This research is aim to know usability aspect of e-commerce banking. Data collection was done by distributing questionnaires in Yogyakarta Special Region. The number of respondents is 140 with the range of age 17-22 years. Anova is used as method research. The results showed that in each group show significantly different. Post hoc analysis explained that learnability and efficiency variable has significantly different, with value p<0,05. The highest average value is in the learnability variable and the lowest is the memorability variable.

  15. Characterization of hepatitis C virus recombinants with chimeric E1/E2 envelope proteins and identification of single amino acids in the E2 stem region important for entry

    DEFF Research Database (Denmark)

    Carlsen, Thomas H R; Scheel, Troels K H; Ramirez, Santseharay

    2013-01-01

    The hepatitis C virus (HCV) envelope proteins E1 and E2 play a key role in host cell entry and represent important targets for vaccine and drug development. Here, we characterized HCV recombinants with chimeric E1/E2 complexes in vitro. Using genotype 1a/2a JFH1-based recombinants expressing 1a....../release. Studies of E1/E2 heterodimerization showed no differences in intracellular E1/E2 interaction for chimeric constructs with or without E2 stem region mutations. Interestingly, the E2 stem region mutations allowed efficient entry, which was verified in 1a-E1/1b-E2 HCV pseudoparticle assays. A CD81 inhibition...

  16. Politics in the Western Maya Region (I: Ajawil/Ajawlel and Ch'e'n

    Directory of Open Access Journals (Sweden)

    Péter Bíró

    2011-01-01

    Full Text Available In a series of articles I reflect on the use of various expressions which are connected to what we call the political in the inscriptions of the Classic Maya Western Region. These words express concepts which help to understand the intricate details of the interactions between the political entities and their internal organisations in the Classic Maya Lowlands. Words such as 7ajawil, 7ajawlel, the kennings built on the base of ch'e7n (cave, pond, the emblem glyphs and titles will be examined in light of what they tell us about the functioning of the political organisation of the Classic Period in a constrained region.En una serie de artículos como éste investigo el uso de varias palabras en las inscripciones mayas de la época Clásica de la Región Occidental vinculadas con lo que nosotros llamamos "política". Estas palabras expresan conceptos que ayudan a entender los matices de las relaciones entre las entidades políticas de las Tierras Bajas Mayas y su organización interna. Términos como ajaw'ü I ajawlel, los difrasismos con base ch'e'n (cueva, pozo, los glifos emblemas y los títulos serán examinados tomando en cuenta la información que nos proporcionan sobre el funcionamiento de la organización política de la época Clásica en una región restringida.

  17. Rocket observation of electron density irregularities in the lower E region

    International Nuclear Information System (INIS)

    Watanabe, Yuzo; Nakamura, Yoshiharu; Amemiya, Hiroshi.

    1990-01-01

    Local ionospheric electron density irregularities in the scale size of 3 m to 300 m have been measured on the ascending path from 74 km to 93 km by a fix biased Langmuir probe on board the S-310-16 sounding rocket. The rocket was launched at 22:40:00 on February 1, 1986 from Kagoshima Space Center in Japan. It is found from frequency analysis of the data that the spectral index of the irregularities is 0.9 to 1.8 and the irregularity amplitude is 1 to 15 %. The altitude where the amplitude reaches its maximum is 88 km. The generation mechanism of these irregularities is explained by the neutral turbulence theory, which indicates that the spectral index is 5/3 and has been confirmed by a chemical release experiment using rockets over India to be valid up to about 110 km. From frequency analysis of the data observed during the descent in the lower E region, we have found that the rocket-wake effect becomes larger when the probe is situated near the edge of the rocket-wake, and that this is also the case even when the rocket-wake effect does not clearly appear in the DC current signal which approximately changes in proportion to the electron density, where the probe is completely situated inside the rocket-wake region. (author)

  18. Auroral lights created by high-power radiowaves in the ionospheric E region

    International Nuclear Information System (INIS)

    Kagan, L M

    2008-01-01

    Artificial auroral lights are optical emissions induced by high-power radiowaves in a manner similar to the creation of natural auroral lights due to precipitation of superthermal electrons. Here the Earth's atmosphere itself plays the role of a plasma laboratory. A high-power radio-transmitter creates superthermal electrons in situ due to radiowave interactions with the ionospheric plasma. Low-altitude (85-125 km) artificial aurora is a relatively rare phenomenon observed for the first time about 10 years ago. Analysis of available observations shows that its intensity and structure, as well as the very possibility of its generation at these altitudes, depend largely on the presence and features of so-called sporadic ionization, best known for its effect on navigation and communication. Thus, all other parameters unchanged, a 20 times increase in the height-extent of sporadic ionization clouds could under certain circumstances result in a 27-fold increase in the intensity of the low-altitude artificial aurora. Understanding the morphology and typical features of sporadic ionization clouds for a given location would allow proper planning of experimental campaigns and noticeably extend our knowledge of the atmosphere and its use for human needs. Equally important is that low-altitude artificial auroras give information about the horizontal structure and dynamics of E-region sporadic ionization, the airglow-source region, the energy of superthermal electrons and perhaps the local atmospheric temperature and water vapor content at 80-90 km

  19. The earthquakes of stable continental regions. Volume 2: Appendices A to E. Final report

    International Nuclear Information System (INIS)

    Johnston, A.C.; Kanter, L.R.; Coppersmith, K.J.; Cornell, C.A.

    1994-12-01

    The objectives of the study were to develop a comprehensive database of earthquakes in stable continental regions (SCRs) and to statistically examine use of the database for the assessment of large earthquake potential. We identified nine major and several minor SCRs worldwide and compiled a database of geologic characteristics of tectonic domains within each SCR. We examined all available earthquake data from SCRs, from historical accounts of events with no instrumental ground-motion data to present-day instrumentally recorded events. In all, 1,385 events were analyzed. Using moment magnitude 4.5 as the lower bound threshold for inclusion in the database, 870 were assigned to an SCR, 124 were found to be transitional to an SCR, and 391 were examined, but rejected. We then performed a seismotectonic analysis to determine what distinguishes seismic activity in SCRs from other types of crust, such as active plate margins or active continental regions. General observations are: (1) SCRs comprise nearly two-thirds of all continental crust of which 25% is considered to be extended (i.e., rifted); (2) the majority of seismic energy release and the largest earthquakes in SCRs have occurred in extended crust; and (3) active plate margins release seismic energy at a rate per unit area approximately 7,000 times the average for non-extended SCRs. Finally, results of a statistical examination of distributions of historical maximum earthquakes between different crustal domain types indicated that additional information is needed in order to adequately constrain estimates of maximum earthquakes for any given region. Thus, a Bayesian approach was developed in which statistical constraints from the database were used to develop a prior distribution, which may then be combined with source-specific information to constrain maximum magnitude assessments for use in probabilistic seismic hazard analyses

  20. Measurement of the e+e- → π+π-π+π- cross section in the rho'(1600) energy region

    International Nuclear Information System (INIS)

    Bacci, C.; De Zorzi, G.; Penso, G.; Stella, B.; Baldini-Celio, R.; Battistoni, G.; Capon, G.; Del Fabbro, R.; Iarocci, E.; Murtas, G.P.

    1980-01-01

    The cross section for the reaction e + e - → π + π - π + π - has been measured at the e + e - storage ring Adone, in the total c.m. energy range 1.42-2.20 GeV. The peak and the following descent of the rho'(1600) resonance is observed. Using also lower energy data, and assuming that only one resonant amplitude contributes to the observed cross section, the parameters of the rho'(1600) are deduced. (orig.)

  1. Morbidade Materna Grave e Near Misses em Hospital de Referência Regional

    Directory of Open Access Journals (Sweden)

    Márcia Lait Morse

    2011-06-01

    Full Text Available OBJETIVO: Analisar perfil epidemiológico da morbidade materna grave/near miss em uma maternidade pública de referência regional, utilizando diferentes critérios identificadores. MÉTODOS: Trata-se de um estudo descritivo de corte transversal dos casos de morbidade materna grave/near miss realizado em Hospital de referência regional entre junho e outubro de 2009, identificados a partir dos livros de registro de internação da maternidade e análise dos prontuários clínicos. Foram estudadas mulheres que, durante a gestação, parto ou puerpério, apresentaram qualquer quadro clínico compatível com os critérios definidores de morbidade materna grave/near miss de Waterstone et al., Mantel et al. e Organização Mundial de Saúde. RESULTADOS: Entre as 1.544 internações foram identificadas 89 mulheres com morbidade materna grave, considerando os critérios adotados. As razões de morbidade materna grave/near miss variaram entre 81,4 a 9,4 por 1.000 NV, dependendo do critério utilizado. O índice de Mortalidade foi de 3,2%, chegando a 23% no critério da OMS. Das 89 mulheres, apenas 40% fizeram mais de seis consultas de pré-natal e 10% não realizaram qualquer consulta. Os marcadores mais encontrados foram a pré-eclâmpsia grave seguida de hemorragia grave, internação em UTI, Síndrome HELLP e eclâmpsia. Ocorreram três mortes maternas por causas obstétricas com RMM de 280/100.000 NV e uma morte tardia. O critério da OMS se mostrou mais específico, identificando os casos mais graves, enquanto o de Waterstone foi mais sensível. CONCLUSÃO: O estudo da morbidade materna grave/near miss em um hospital de referência regional pode contribuir para o conhecimento da magnitude deste evento, como também identificar suas características e condições clínicas mais frequentes, sendo extremamente importante para o enfrentamento da morbi-mortalidade materna.OBJECTIVE: To investigate severe maternal morbidity/near misses in a tertiary

  2. Southern high-latitude Digisonde observations of ionosphere E-region Bragg scatter during intense lacuna conditions

    Directory of Open Access Journals (Sweden)

    D. P. Monselesan

    2004-09-01

    Full Text Available During summer months at solar cycle minimum, F-region lacuna and slant-Es conditions (SEC are common features of daytime ionograms recorded around local magnetic noon at Casey, Antarctica. Digisonde measurements of drift velocity height profiles show that the occurrence of lacuna prevents the determination of F-region drift velocities and also affects E-region drift velocity measurements. Unique E-region spectral features revealed as intervals of Bragg scatter superimposed on typical background E-region reflection were observed in Digisonde Doppler spectra during intense lacuna conditions. Daytime E-region Doppler spectra recorded at carrier frequencies from 1.5 to 2.7MHz, below the E-region critical frequency foE, have two side-peaks corresponding to Bragg scatter at approximately ±1-2Hz symmetrically located on each side of a central-peak corresponding to near-zenith total reflections. Angle-of-arrival information and ray-tracing simulations show that echo returns are coming from oblique directions most likely resulting from direct backscatter from just below the total reflection height for each sounding frequency. The Bragg backscatter events are shown to manifest during polar lacuna conditions, and to affect the determination of E-region background drift velocities, and as such must be considered when using standard Doppler-sorted interferometry (DSI techniques to estimate ionospheric drift velocities. Given the Doppler and spatial separation of the echoes determined from high-resolution Doppler measurements, we are able to estimate the Bragg scatter phase velocity independently from the bulk E-region motion. The phase velocity coincides with the ExB direction derived from in situ fluxgate magnetometer records. When ionospheric refraction is considered, the phase velocity amplitudes deduced from DSI are comparable to the ion-acoustic speed expected in the E-region. We briefly consider the plausibility that these

  3. Il SIT della Regione Puglia, uno strumento a beneficio dei comuni e degli enti locali della Regione

    Directory of Open Access Journals (Sweden)

    Valeria De Vecchi

    2009-03-01

    for the italian Puglia region. It will help this public organization to better plan and manage the land and the environment of that part of Italy. The possibility to share land informations is one of the mail features of the system: this will be extremely helpful for the government activities and to fullfill land knowledge with precise and homogeneous data.

  4. The interaction between stratospheric monthly mean regional winds and sporadic-E

    International Nuclear Information System (INIS)

    Çetin, Kenan; Korlaelçi, Serhat; Özcan, Osman

    2017-01-01

    In the present study, a statistical investigation is carried out to explore whether there is a relationship between the critical frequency (foEs) of the sporadic-E layer that is occasionally seen on the E region of the ionosphere and the quasi-biennial oscillation (QBO) that flows in the east–west direction in the equatorial stratosphere. Multiple regression model as a statistical tool was used to determine the relationship between variables. In this model, the stationarity of the variables (foEs and QBO) was firstly analyzed for each station (Cocos Island, Gibilmanna, Niue Island, and Tahiti). Then, a co-integration test was made to determine the existence of a long-term relationship between QBO and foEs. After verifying the presence of a long-term relationship between the variables, the magnitude of the relationship between variables was further determined using the multiple regression model. As a result, it is concluded that the variations in foEs were explainable with QBO measured at 10 hPa altitude at the rate of 69%, 94%, 79%, and 58% for Cocos Island, Gibilmanna, Niue Island, and Tahiti stations, respectively. It is observed that the variations in foEs were explainable with QBO measured at 70 hPa altitude at the rate of 66%, 69%, 53%, and 47% for Cocos Island, Gibilmanna, Niue Island, and Tahiti stations, respectively. (paper)

  5. Southern high-latitude Digisonde observations of ionosphere E-region Bragg scatter during intense lacuna conditions

    Directory of Open Access Journals (Sweden)

    D. P. Monselesan

    2004-09-01

    Full Text Available During summer months at solar cycle minimum, F-region lacuna and slant-Es conditions (SEC are common features of daytime ionograms recorded around local magnetic noon at Casey, Antarctica. Digisonde measurements of drift velocity height profiles show that the occurrence of lacuna prevents the determination of F-region drift velocities and also affects E-region drift velocity measurements. Unique E-region spectral features revealed as intervals of Bragg scatter superimposed on typical background E-region reflection were observed in Digisonde Doppler spectra during intense lacuna conditions. Daytime E-region Doppler spectra recorded at carrier frequencies from 1.5 to 2.7MHz, below the E-region critical frequency foE, have two side-peaks corresponding to Bragg scatter at approximately ±1-2Hz symmetrically located on each side of a central-peak corresponding to near-zenith total reflections. Angle-of-arrival information and ray-tracing simulations show that echo returns are coming from oblique directions most likely resulting from direct backscatter from just below the total reflection height for each sounding frequency. The Bragg backscatter events are shown to manifest during polar lacuna conditions, and to affect the determination of E-region background drift velocities, and as such must be considered when using standard Doppler-sorted interferometry (DSI techniques to estimate ionospheric drift velocities. Given the Doppler and spatial separation of the echoes determined from high-resolution Doppler measurements, we are able to estimate the Bragg scatter phase velocity independently from the bulk E-region motion. The phase velocity coincides with the ExB direction derived from in situ fluxgate magnetometer records. When ionospheric refraction is considered, the phase velocity amplitudes deduced from DSI are comparable to the ion-acoustic speed expected in the E-region. We briefly consider the plausibility that these previously unreported polar

  6. E and F region study of the evening sector auroral oval: A Chatanika/Dynamics Explorer 2/NOAA 6 comparison

    International Nuclear Information System (INIS)

    Senior, C.; Sharber, J.R.; Winningham, J.D.; De La Beaujardiere, O.; Heelis, R.A.; Evans, D.S.; Sugiura, M.; Hoegy, W.R.

    1987-01-01

    Simultaneous data obtained with the Chatanika incoherent scatter radar and the Dynamics Explorer 2 (DE 2) and NOAA 6 satellites are used to relate the locations of the precipitating particles, field-aligned currents, and E and F region ionization structures in the evening-sector auroral oval. The auroral E layer observed by the radar extends about 2 degree equatorward of the electron precipitation region, and its equatorward edge coincides with the equatorward edges of the region 2 field-aligned current and intense convection region (E ≅ 50 mV/m). It is shown that precipitating protons are responsible for part of the E region ionization within the electron precipitation region as well as south of it. E region density profiles calculated from ion spectra measured by the DE 2 and NOAA 5 satellites are in fairly good agreement with the Chatanika data. in the F region, a channel of enhanced ionization density, elongated along the east-west direction and having a width of about 100 km, marks the poleward edge of the main trough. it is colocated with the equatorward boundary of the electron precipitation from the central plasma sheet. Although enhanced fluxes of soft electrons are observed at this boundary, the energy input to the ionospheric electron gas, calculated from the radar data, shows that this ionization channel is not locally produced by this soft precipitation, but that it is rather a convected feature. In fact, both the trough and the ionization channel are located in a region where the plasma flows sunward at high speed, but the flux tubes associated with theses two features have different convective time histories. Keeping in mind that several processes operate together in the F region, the data set is consistent with the included trough and ionization channel formation mechanisms

  7. Regionalism, Regionalization and Regional Development

    Directory of Open Access Journals (Sweden)

    Liviu C. Andrei

    2016-03-01

    Full Text Available Sustained development is a concept associating other concepts, in its turn, in the EU practice, e.g. regionalism, regionalizing and afferent policies, here including structural policies. This below text, dedicated to integration concepts, will limit on the other hand to regionalizing, otherwise an aspect typical to Europe and to the EU. On the other hand, two aspects come up to strengthen this field of ideas, i.e. the region (al-regionalism-(regional development triplet has either its own history or precise individual outline of terms.

  8. High-resolution backscatter power observations of 440-MHz E region coherent echoes at Millstone Hill

    International Nuclear Information System (INIS)

    Foster, J.C.; Tetenbaum, D.

    1991-01-01

    A 40-μs pulse length has been used to provide 10-s temporal and 6-km range resolution observations of E region coherent backscatter from the premidnight eastward electrojet region to the north of Millstone Hill. The observations can be divided into two categories: strong events in which the backscattered amplitude nears saturation and weak events in which spatial structure and large-amplitude variations are common. Calibrated observations find a typical volume scattering coefficient of ∼10 -11 m -1 at 440 MHz during strong events with a maximum level of 9 x 10 -10 m -1 observed for brief intervals. During less intense events the radar backscatter is modulated by ∼30dB in amplitude at Pc 5 frequencies (150-500 s) by waves with spatial wavelength 50-100 km. The observations support the premise that the weak irregularities grow linearly with electric field strength and reach a saturation amplitude beyond which the oscillating electric field of the Pc pulsation has little effect. The observed variation of backscattered power with range is interpreted using a geometrical model which accounts for the detailed antenna beam pattern, a magnetic aspect angle sensitivity of -10 dB per degree, and a thin layer of irregularities centered at 110 km altitude. For strongly driven conditions a comparison of the range variation of backscattered power with the thin layer model suggests that the signal power becomes increasingly dominated by strong scatters confined to a narrower altitude range. The apparent altitude extent of the strongest irregularities decreases by a factor of 2 as the amplitude of the backscattered signal increases by a factor of 10

  9. Calibration and validation of the advanced E-Region Wind Interferometer

    Directory of Open Access Journals (Sweden)

    S. K. Kristoffersen

    2013-07-01

    Full Text Available The advanced E-Region Wind Interferometer (ERWIN II combines the imaging capabilities of a CCD detector with the wide field associated with field-widened Michelson interferometry. This instrument is capable of simultaneous multi-directional wind observations for three different airglow emissions (oxygen green line (O(1S at a height of ~97 km, the PQ(7 and P(7 emission lines in the O2(0–1 atmospheric band at ~93 km and P1(3 emission line in the (6, 2 hydroxyl Meinel band at ~87 km on a three minute cadence. In each direction, for 45 s measurements for typical airglow volume emission rates, the instrument is capable of line-of-sight wind precisions of ~1 m s−1 for hydroxyl and O(1S and ~4 m s−1 for O2. This precision is achieved using a new data analysis algorithm which takes advantage of the imaging capabilities of the CCD detector along with knowledge of the instrument phase variation as a function of pixel location across the detector. This instrument is currently located in Eureka, Nunavut as part of the Polar Environment Atmospheric Research Laboratory (PEARL (80°N, 86° W. The details of the physical configuration, the data analysis algorithm, the measurement calibration and validation of the observations from December 2008 and January 2009 are described. Field measurements which demonstrate the capabilities of this instrument are presented. To our knowledge, the wind determinations with this instrument are the most accurate and have the highest observational cadence for airglow wind observations of this region of the atmosphere and match the capabilities of other wind-measuring techniques.

  10. Investigation of Electron Density Profile in the ionospheric D and E region by Kagoshima rocket experiment

    Science.gov (United States)

    Ashihara, Y.; Ishisaka, K.; Miyake, T.; Okada, T.; Nagano, I.; Abe, T.; Ono, T.

    2007-12-01

    The radio wave propagation characteristic in the lower ionosphere is important because of its effect on commercial radio communication, navigation, and broadcast services. The electron density is of primary interest in this region because the high ion-neutral collision frequencies result in radio wave absorption. In order to investigate the ionization structure in the ionospheric D and E region by using the propagation characteristics of MF-band and LF-band radio waves, S-310-37 and S-520-23 sounding rocket experiments have been carried out at Uchinoura Space Center (USC). S-310-37 sounding rocket was launched at 11:20 LT on January 16, 2007. The apex of rocket trajectory was about 138 km. Then S-520-23 sounding rocket was launched at 19:20 LT on September 2, 2007. The apex was about 279 km. As a common measurement, these sounding rockets measure the fields intensities and the waveform of radio waves from NHK Kumamoto broadcasting station (873kHz, 500kW) and JJY signals from Haganeyama LF radio station (60kHz, 50kW). The approximate electron density profile can be determined from the comparison between these experimental results and propagation characteristics calculated by the full wave method. We will get the most probable electron density profile in the ionosphere. In presentation, we will show the propagation characteristic of LF/MF radio waves measured by two sounding rocket experiments. Then we will discuss the analysis method and the estimated electron density profile in the ionosphere.

  11. Angular analysis of the B-0 -> K*(0) e(+) e(-) decay in the low-q(2) region

    NARCIS (Netherlands)

    Aaij, R.; Adeva, B.; Adinolfi, M.; Affolder, A.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; An, L.; Anderlini, L.; Andreassen, R.; Andreotti, M.; Andrews, J. E.; Appleby, R. B.; Gutierrez, O. Aquines; Archilli, F.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Batozskaya, V.; Battista, V.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Belogurov, S.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bertolin, A.; Bettler, M. -O.; van Beuzekom, M.; Bien, A.; Bifani, S.; Bird, T.; Bizzeti, A.; Blake, T.; Blanc, F.; Blouw, J.; Blusk, S.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Borsato, M.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Brett, D.; Britsch, M.; Britton, T.; Brodzicka, J.; Brook, N. H.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Calabrese, R.; Calvi, M.; Calvo Gomez, M.; Campana, P.; Perez, D. Campora; Capriotti, L.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carson, L.; Carvalho Akiba, K.; Casanova Mohr, R. C. M.; Casse, G.; Cassina, L.; Garcia, L. Castillo; Cattaneo, M.; Cauet, Ch.; Cenci, R.; Charles, M.; Charpentier, Ph.; Chefdeville, M.; Cheung, S. -F.; Chiapolini, N.; Chrzaszcz, M.; Vidal, X. Cid; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coco, V.; Cogan, J.; Cogneras, E.; Cogoni, V.; Cojocariu, L.; Collazuol, G.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombes, M.; Coquereau, S.; Corti, G.; Corvo, M.; Counts, I.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Crocombe, A. C.; Cruz Torres, M.; Cunliffe, S.; Currie, R.; D'Ambrosio, C.; Dalseno, J.; David, P.; David, P. N. Y.; Davis, A.; De Bruyn, K.; De Capua, S.; De Cian, M.; De Miranda, J. M.; De Paula, L.; De Silva, W.; De Simone, P.; Dean, C. -T.; Decamp, D.; Deckenhoff, M.; Del Buono, L.; Deleage, N.; Derkach, D.; Deschamps, O.; Dettori, F.; Dey, B.; Di Canto, A.; Di Domenico, A.; Di Ruscio, F.; Donleavy, S.; Dordei, F.; Dorigo, M.; Dosil Suarez, A.; Dossett, D.; Dovbnya, A.; Dreimanis, K.; Dujany, G.; Dupertuis, F.; Durante, P.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; El Rifai, I.; Elsasser, Ch.; Ely, S.; Esen, S.; Evans, H. M.; Evans, T.; Falabella, A.; Faerber, C.; Farinelli, C.; Farley, N.; Farry, S.; Fay, R.; Ferguson, D.; Fernandez Albor, V.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fiore, M.; Fiorini, M.; Firlej, M.; Fitzpatrick, C.; Fiutowski, T.; Fol, P.; Fontana, M.; Fontanelli, F.; Forty, R.; Francisco, O.; Frei, C.; Frosini, M.; Furfaro, E.; Gallas Torreira, A.; Galli, D.; Gallorini, S.; Gambetta, S.; Gandelman, M.; Gandini, P.; Garcia Pardinas, J.; Garofoli, J.; Tico, J. Garra; Garrido, L.; Gascon, D.; Gaspar, C.; Gastaldi, U.; Gauld, R.; Gavardi, L.; Gazzoni, G.; Geraci, A.; Gersabeck, E.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gianelle, A.; Giani, S.; Gibson, V.; Giubega, L.; Gligorov, V. V.; Goebel, C.; Golubkov, D.; Golutvin, A.; Gotti, C.; Gandara, M. Grabalosa; Graciani Diaz, R.; Cardoso, L. A. Granado; Grauges, E.; Graverini, E.; Graziani, G.; Grecu, A.; Greening, E.; Gregson, S.; Griffith, P.; Grillo, L.; Gruenberg, O.; Gui, B.; Gushchin, E.; Guz, Yu.; Gys, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hamilton, B.; Hampson, T.; Han, X.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; He, J.; Head, T.; Heijne, V.; Hennessy, K.; Henrard, P.; Henry, L.; Hernando Morata, J. A.; van Herwijnen, E.; Hess, M.; Hicheur, A.; Hill, D.; Hoballah, M.; Hombach, C.; Hulsbergen, W.; Hussain, N.; Hutchcroft, D.; Hynds, D.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jalocha, J.; Jans, E.; Jawahery, A.; Jing, F.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Jurik, N.; Kandybei, S.; Kanso, W.; Karacson, M.; Karbach, T. M.; Karodia, S.; Kelsey, M.; Kenyon, I. R.; Kenzie, M.; Ketel, T.; Khanji, B.; Khurewathanakul, C.; Klaver, S.; Klimaszewski, K.; Kochebina, O.; Kolpin, M.; Komarov, I.; Koppenburg, P.; Korolev, M.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kucewicz, W.; Kucharczyk, M.; Kudryavtsev, V.; Kurek, K.; Kvaratskheliya, T.; La Thi, V. N.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lambert, D.; Lambert, R. W.; Lanfranchi, G.; Langenbruch, C.; Langhans, B.; Latham, T.; Lazzeroni, C.; Le Gac, R.; van Leerdam, J.; Lees, J. -P.; Lefevre, R.; Leflat, A.; Lefrancois, J.; Leroy, O.; Lesiak, T.; Leverington, B.; Likhomanenko, T.; Liles, M.; Lindner, R.; Linn, C.; Lionetto, F.; Lohn, S.; Longstaff, I.; Lopes, J. H.; Lowdon, P.; Lucchesi, D.; Luo, H.; Lupato, A.; Luppi, E.; Lupton, O.; Machefert, F.; Machikhiliyan, I. V.; Maciuc, F.; Maev, O.; Malde, S.; Malinin, A.; Manca, G.; Mancinelli, G.; Manning, P.; Mapelli, A.; Maratas, J.; Marchand, J. F.; Marconi, U.; Marin Benito, C.; Marino, P.; Maerki, R.; Marks, J.; Martellotti, G.; Martinelli, M.; Santos, D. Martinez; Martinez Vidal, F.; Martins Tostes, D.; Massafferri, A.; Matev, R.; Mathe, Z.; Matteuzzi, C.; Maurin, B.; Mazurov, A.; McCann, M.; McCarthy, J.; McNab, A.; McNulty, R.; McSkelly, B.; Meadows, B.; Meier, F.; Merk, M.; Milanes, D. A.; Minard, M. -N.; Moggi, N.; Molina Rodriguez, J.; Monteil, S.; Morandin, M.; Morawski, P.; Morda, A.; Morello, M. J.; Moron, J.; Morris, A. -B.; Mountain, R.; Muheim, F.; Mueller, K.; Mussini, M.; Muster, B.; Naik, P.; Nakada, T.; Nandakumar, R.; Nasteva, I.; Needham, M.; Neri, N.; Neubert, S.; Neufeld, N.; Neuner, M.; Nguyen, A. D.; Nguyen-Mau, C.; Nicol, M.; Niess, V.; Niet, R.; Nikitin, N.; Nikodem, T.; Novoselov, A.; O'Hanlon, D. P.; Oblakowska-Mucha, A.; Obraztsov, V.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Onderwater, C. J. G.; Orlandea, M.; Osorio Rodrigues, B.; Otalora Goicochea, J. M.; Otto, A.; Owen, P.; Oyanguren, A.; Pal, B. K.; Palano, A.; Palombo, F.; Palutan, M.; Papanestis, A.; Pappagallo, M.; Pappalardo, L. L.; Parkes, C.; Parkinson, C. J.; Passaleva, G.; Patel, G. D.; Patrignani, C.; Pearce, A.; Pellegrino, A.; Penso, G.; Altarelli, M. Pepe; Perazzini, S.; Perret, P.; Pescatore, L.; Pesen, E.; Petridis, K.; Petrolini, A.; Picatoste Olloqui, E.; Pietrzyk, B.; Pilar, T.; Pinci, D.; Pistone, A.; Playfer, S.; Plo Casasus, M.; Polci, F.; Poluektov, A.; Polyakov, I.; Polycarpo, E.; Popov, A.; Popov, D.; Popovici, B.; Potterat, C.; Price, E.; Price, J. D.; Prisciandaro, J.; Pritchard, A.; Prouve, C.; Pugatch, V.; Navarro, A. Puig; Punzi, G.; Qian, W.; Quagliani, R.; Rachwal, B.; Rademacker, J. H.; Rakotomiaramanana, B.; Rama, M.; Rangel, M. S.; Raniuk, I.; Rauschmayr, N.; Raven, G.; Redi, F.; Reichert, S.; Reid, M. M.; dos Reis, A. C.; Ricciardi, S.; Richards, S.; Rihl, M.; Rinnert, K.; Rives Molina, V.; Rodrigues, A. B.; Rodrigues, E.; Perez, P. Rodriguez; Roiser, S.; Romanovsky, V.; Romero Vidal, A.; Rotondo, M.; Rouvinet, J.; Ruf, T.; Ruiz, H.; Ruiz Valls, P.; Saborido Silva, J. J.; Sagidova, N.; Sail, P.; Saitta, B.; Salustino Guimaraes, V.; Sanchez Mayordomo, C.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santovetti, E.; Sarti, A.; Satriano, C.; Satta, A.; Saunders, D. M.; Savrina, D.; Schindler, H.; Schlupp, M.; Schmelling, M.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M. -H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Semennikov, A.; Sepp, I.; Serra, N.; Serrano, J.; Sestini, L.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, V.; Shires, A.; Coutinho, R. Silva; Simi, G.; Sirendi, M.; Skidmore, N.; Skillicorn, I.; Skwarnicki, T.; Smith, N. A.; Snoek, H.; Sokoloff, M. D.; Soler, F. J. P.; Soomro, F.; Souza, D.; Souza De Paula, B.; Spaan, B.; Spradlin, P.; Sridharan, S.; Stagni, F.; Stahl, M.; Stahl, S.; Steinkamp, O.; Stenyakin, O.; Sterpka, F.; Stevenson, S.; Stone, S.; Storaci, B.; Stracka, S.; Straticiuc, M.; Straumann, U.; Stroili, R.; Sutcliffe, W.; Swientek, K.; Swientek, S.; Syropoulos, V.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Teklishyn, M.; Tellarini, G.; Teubert, F.; van Tilburg, J.; Tisserand, V.; Tobin, M.; Todd, J.; Tolk, S.; Tomassetti, L.; Tonelli, D.; Topp-Joergensen, S.; Torr, N.; Tournefier, E.; Tourneur, S.; Trabelsi, K.; Tresch, M.; Trisovic, A.; Tsaregorodtsev, A.; Tsopelas, P.; Tuning, N.; Garcia, M. Ubeda; Ukleja, A.; Ustyuzhanin, A.; Uwer, U.; Vacca, C.; Vagnoni, V.; Valenti, G.; Vallier, A.; Gomez, R. Vazquez; Vazquez Regueiro, P.; Vazquez Sierra, C.; Vecchi, S.; Velthuis, J. J.; Veltri, M.; Veneziano, G.; Vesterinen, M.; Barbosa, J. V. V. B. Viana; Viaud, B.; Vieira, D.; Vieites Diaz, M.; Vilasis-Cardona, X.; Vollhardt, A.; Volyanskyy, D.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voss, C.; Waldi, R.; Wallace, C.; Wallace, R.; Wandernoth, S.; Ward, D. R.; Watson, N. K.; Websdale, D.; Whitehead, M.; Wiedner, D.; Wilkinson, G.; Wilschut, H. W.; Wilson, F. F.; Wimberley, J.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wright, S.; Wyllie, K.; Xie, Y.; Xing, Z.; Yang, Z.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zavertyaev, M.; Zhang, W. C.; Zhelezov, A.; Zhokhov, A.; Zhong, L.

    2015-01-01

    An angular analysis of the B-0 -> K(*0)e(+) e(-) decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 fb(-1), collected by the LHCb experiment in pp collisions at centre-of-mass energies of 7 and 8TeV during 2011 and 2012. For the first time several observables

  12. CUTLASS HF radar observations of high-velocity E-region echoes

    Directory of Open Access Journals (Sweden)

    M. V. Uspensky

    Full Text Available A short event of high-velocity E-region echo observations by the Pykkvibaer HF radar is analysed to study echo parameters and the echo relation to the Farley-Buneman plasma instability. The echoes were detected in several beams aligned closely to the magnetic L-shell direction. Two echo groups were identified: one group corresponded to the classical type 1 echoes with velocities close to the nominal ion-acoustic speed of 400 ms1 , while the other group had significantly larger velocities, of the order of 700 ms1 . The mutual relationship between the echo power, Doppler velocity, spectral width and elevation angles for these two groups was studied. Plotting of echo parameters versus slant range showed that all ~700 ms1 echoes originated from larger heights and distances of 500–700 km, while all ~400 ms1 echoes came from lower heights and from farther distances; 700–1000 km. We argue that both observed groups of echoes occurred due to the Farley-Buneman plasma instability excited by strong ( ~70 mVm1 and uniformly distributed electric fields. We show that the echo velocities for the two groups were different because the echoes were received from different heights. Such a separation of echo heights occurred due to the differing amounts of ionospheric refraction at short and large ranges. Thus, the ionospheric refraction and related altitude modulation of ionospheric parameters are the most important factors to consider, when various characteristics of E-region decametre irregularities are derived from HF radar measurements.

    Key words. Ionosphere (ionospheric irregularities; plasma waves and instabilities; polar ionosphere

  13. The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif

    Directory of Open Access Journals (Sweden)

    Grishin Nick V

    2009-01-01

    Full Text Available Abstract Background Argonaute (Ago proteins interact with small regulatory RNAs to mediate gene regulatory pathways. A recent report by Kiriakidou et al. 1 describes an MC sequence region identified in Ago2 that displays similarity to the cap-binding motif in translation initiation factor 4E (eIF4E. In a cap-bound eIF4E structure, two important aromatic residues of the motif stack on either side of a 7-methylguanosine 5'-triphosphate (m7Gppp base. The corresponding Ago2 aromatic residues (F450 and F505 were hypothesized to perform the same cap-binding function. However, the detected similarity between the MC sequence and the eIF4E cap-binding motif was questionable. Results A number of sequence-based and structure-based bioinformatics methods reveal the reported similarity between the Ago2 MC sequence region and the eIF4E cap-binding motif to be spurious. Alternatively, the MC sequence region is confidently assigned to the N-terminus of the Ago piwi module, within the mid domain of experimentally determined prokaryotic Ago structures. Confident mapping of the Ago2 MC sequence region to the piwi mid domain results in a homology-based structure model that positions the identified aromatic residues over 20 Å apart, with one of the aromatic side chains (F450 contributing instead to the hydrophobic core of the domain. Conclusion Correct functional prediction based on weak sequence similarity requires substantial evolutionary and structural support. The evolutionary context of the Ago mid domain suggested by multiple sequence alignment is limited to a conserved hydrophobicity profile required for the fold and a motif following the MC region that binds guide RNA. Mapping of the MC sequence to the mid domain structure reveals Ago2 aromatics that are incompatible with eIF4E-like mRNA cap-binding, yet display some limited local structure similarities that cause the chance sequence match to eIF4E. Reviewers This article was reviewed by Arcady Mushegian

  14. A televisão na Amazônia e sua contribuição ao desenvolvimento regional

    Directory of Open Access Journals (Sweden)

    Berno, Geovani

    2005-01-01

    Full Text Available Este artigo procede de análise e observação da história da televisão na Amazônia brasileira, a acuidade dessa mídia para a miscigenação cultural, a construção de novos sentidos e a interferência na cultura local e sua contribuição para o desenvolvimento regional

  15. Out-of-hospital cardiac arrest: the prospect of E-CPR in the Maastricht region.

    Science.gov (United States)

    Sharma, A S; Pijls, R W M; Weerwind, P W; Delnoij, T S R; de Jong, W C; Gorgels, A P M; Maessen, J G

    2016-02-01

    The current outcome of out-of-hospital cardiac arrest (OHCA) patients in the Maastricht region was analysed with the prospect of implementing extracorporeal cardiopulmonary resuscitation (E-CPR). A retrospective analysis of adult patients who were resuscitated for OHCA during a 24-month period was performed. 195 patients (age 66 [57-75] years, 82 % male) were resuscitated for OHCA by the emergency medical services and survived to admission at the emergency department. Survival to hospital discharge was 46.2 %. Notable differences between non-survivors and survivors were observed and included: age (70 [58-79] years) vs. (63 [55-72] years, p = 0.01), chronic heart failure (18 vs. 7 %, p = 0.02), shockable rhythm (67 vs. 99 %, p < 0.01), and return of spontaneous circulation (ROSC) at departure from the site of the arrest (46 vs. 99 %, p < 0.01) and on arrival to the emergency department (43 vs. 98 %, p < 0.01), respectively. Acute coronary syndrome was diagnosed in 32 % of non-survivors vs. 59 % among survivors, p < 0.01. Therapeutic hypothermia was provided in non-survivors (20 %) vs. survivors (43 %), p < 0.01. Percutaneous coronary intervention (PCI) was performed in 14 % of non-survivors while 52 % of survivors received PCI (p < 0.01). No statistical significance was observed in terms of gender, witnessed arrest, bystander CPR, or automated external defibrillator deployed among the cohort. At hospital discharge, moderately severe neurological disability was present in six survivors. These observations are compatible with the notion that a shockable rhythm, ROSC, and post-arrest care improve survival outcome. Potentially, initiating E-CPR in the resuscitation phase in patients with a shockable rhythm and no ROSC might serve as a bridge to definite treatment and improve survival outcome.

  16. Search for narrow resonances in e+e- annihilation in the mass region 3.2 to 5.9 GeV

    International Nuclear Information System (INIS)

    Boyarski, A.M.; Breidenbach, M.; Bulos, F.

    1975-01-01

    The mass region 3.2 to 5.9 GeV was searched for evidence of narrow resonances in e + e - /sub f/ → hadron. No evidence was found for any such resonances other than the psi (3695) in this region with a sensitivity ranging from about 12 to 45 percent of the integrated cross section of the psi (3695). The more stringent bounds apply to resonances of a few MeV width, while the looser bounds apply to resonances of up to 20 MeV width. (U.S.)

  17. The equatorial E-region and its plasma instabilities: a tutorial

    Directory of Open Access Journals (Sweden)

    D. T. Farley

    2009-04-01

    Full Text Available In this short tutorial we first briefly review the basic physics of the E-region of the equatorial ionosphere, with emphasis on the strong electrojet current system that drives plasma instabilities and generates strong plasma waves that are easily detected by radars and rocket probes. We then discuss the instabilities themselves, both the theory and some examples of the observational data. These instabilities have now been studied for about half a century (!, beginning with the IGY, particularly at the Jicamarca Radio Observatory in Peru. The linear fluid theory of the important processes is now well understood, but there are still questions about some kinetic effects, not to mention the considerable amount of work to be done before we have a full quantitative understanding of the limiting nonlinear processes that determine the details of what we actually observe. As our observational techniques, especially the radar techniques, improve, we find some answers, but also more and more questions. One difficulty with studying natural phenomena, such as these instabilities, is that we cannot perform active cause-and-effect experiments; we are limited to the inputs and responses that nature provides. The one hope here is the steadily growing capability of numerical plasma simulations. If we can accurately simulate the relevant plasma physics, we can control the inputs and measure the responses in great detail. Unfortunately, the problem is inherently three-dimensional, and we still need somewhat more computer power than is currently available, although we have come a long way.

  18. Auroral zone E-region conductivities during solar minimum derived from EISCAT data

    International Nuclear Information System (INIS)

    Schlegel, K.

    1988-01-01

    From two years of EISCAT data (1985-1986, a period of low solar activity) 8337 E-region conductivity profiles have been calculated as 5-min averages. From these profiles the height of the conductivity maxima for the Hall and Pedersen conductivities (H max ), the height-integrated Hall and Pedersen conductivities and the ratio of both have been computed. Histograms as well as average values of these quantities are displayed as a function of K p and of magnetic local time. The former results showed quantitatively the increase of the conductivities and the decrease of H max with increasing magnetic activity. The latter results revealed that on the average the conductivities are maximal in the early morning hours due to hard particle precipitation, H max being affected both by the solar zenith angle and by particle precipitation. The solar zenith angle dependence of the conductivities is only significant for low K p -values. Latitudinal profiles of the height-integrated conductivities show quantitatively the southward shift of the average conductivity maximum with increasing magnetic activity

  19. Semidiurnal tide in the E region from incoherent scatter measurements at Arecibo

    International Nuclear Information System (INIS)

    Wand, R.H.

    1976-01-01

    A five-pulse technique was implemented for the 430 MHz incoherent scatter radar at Arecibo Observatory (18.3 0 N) to explore the detailed thermal structure of the E region from 105 to 130 km with an altitude resolution of 3 km. Five days of measurements in Sept-Oct 1970 showed long-period temperature fluctuations having a downward phase progression. The temperature oscillations are interpreted as manifestations of a semidiurnal tide which is quite stable over a 12-day period, together with a superimposed spectrum of shorter-period gravity waves which are randomly phased from day to day. The semidiurnal tide increased to a maximum amplitude of 17 percent of the mean temperature near 115 km and decreased above this altitude as dissipative effects became important. The vertical wavelength, deduced from the altitude variation of semidiurnal tidal phase, showed a smooth increase from about 20 km at an altitude of 109 km to about 50 km at an altitude of 127 km. No ready interpretation of the observed tidal characteristics was possible in terms of present theories for the semidiurnal tide. Altitude profiles of mean daytime temperature and ion-neutral collision frequency were also obtained from the measurements. The mean temperature gradient between 115 and 130 km was 15 K/km, which is somewhat larger than that given by current atmospheric models

  20. Temporal distribution of earthquakes using renewal process in the Dasht-e-Bayaz region

    Science.gov (United States)

    Mousavi, Mehdi; Salehi, Masoud

    2018-01-01

    Temporal distribution of earthquakes with M w > 6 in the Dasht-e-Bayaz region, eastern Iran has been investigated using time-dependent models. Based on these types of models, it is assumed that the times between consecutive large earthquakes follow a certain statistical distribution. For this purpose, four time-dependent inter-event distributions including the Weibull, Gamma, Lognormal, and the Brownian Passage Time (BPT) are used in this study and the associated parameters are estimated using the method of maximum likelihood estimation. The suitable distribution is selected based on logarithm likelihood function and Bayesian Information Criterion. The probability of the occurrence of the next large earthquake during a specified interval of time was calculated for each model. Then, the concept of conditional probability has been applied to forecast the next major ( M w > 6) earthquake in the site of our interest. The emphasis is on statistical methods which attempt to quantify the probability of an earthquake occurring within a specified time, space, and magnitude windows. According to obtained results, the probability of occurrence of an earthquake with M w > 6 in the near future is significantly high.

  1. Comparison of π±, K± and p, anti p production in the central rapidity region in hadron-hadron collisions and in e+e- annihilation

    International Nuclear Information System (INIS)

    Aihara, H.; Enomoto, R.; Fujii, T.; Kamae, T.; Takahashi, T.; Toge, N.; Alston-Garnjost, M.; Avery, R.E.; Barbaro-Galtieri, A.; Barnes, A.V.; Bolognese, T.S.; Bross, A.D.; Clark, A.R.; Cowan, G.D.; Dahl, O.L.; Derby, K.A.; Eastman, J.J.; Eberhard, P.H.; Edberg, T.K.; Gary, J.W.; Hofmann, W.; Huth, J.E.; Kaye, H.S.; Kenney, R.W.; Kerth, L.T.; Loken, S.C.; Lynch, G.R.; Madaras, R.J.; Marx, J.N.; Mathis, L.G.; Moses, W.; Nygren, D.R.; Oddone, P.J.; Pripstein, M.; Ronan, M.T.; Ross, R.R.; Rouse, F.R.; Shapiro, G.; Shapiro, M.D.; Stevenson, M.L.; Van Tyen, R.; Wagner, W.; Wang, E.M.; Wenzel, W.A.; Wolf, Z.R.; Yamamoto, H.; Barker, A.R.; Bauer, D.A.; Caldwell, D.O.; Lu, A.; Schwitkis, K.A.; Wang, Y.X.; Yellin, S.J.; Barnett, B.A.; Crane, D.A.; Hylen, J.; Lu, X.Q.; Matthews, J.A.J.; Zhang, W.M.; Bengtsson, H.U.; Buchanan, C.D.; Koda, R.I.; Park, D.A.; Slater, W.E.; Steinman, J.S.; Stork, D.H.; Strauss, M.G.; Van Daalen Wetters, R.R.; Wayne, M.R.; Bintinger, D.L.; Kees, K.H.; Masek, G.E.; Miller, E.S.; Thompson, J.R.; Vernon, W.; White, J.T.; Bobbink, G.J.; Buijs, A.; Erne, F.C.; Linde, F.L.; Paar, H.P.; Sens, J.C.; Uitert, B. van; Eisner, A.M.; Magnuson, B.D.; Sullivan, M.K.; Hauptman, J.M.; Park, S.K.; Ko, W.; Lander, R.L.; Maeshima, K.; McNeil, R.R.; Pellet, D.E.; Smith, J.R.; Williams, M.S.C.; Zeitlin, C.; Kofler, R.R.; Maxfield, S.J.; Toutounchi, S.; Nemethy, P.

    1987-01-01

    We compare the p T dependence of pion, kaon and proton production cross sections in the central rapidity region in e + e - annihilation events and in proton-proton collisions at ISR energies. We find similarities both in the p T dependence of cross sections and in the particle composition as a function of p T , in agreement with the hypothesis of a universal mechanism of particle production. (orig.)

  2. Search for tiny or transient sources in the Galaxy's central regions with H.E.S.S. - Application to the study of supernova W49B's remnant region

    International Nuclear Information System (INIS)

    Brun, F.

    2011-09-01

    H.E.S.S. (High Energy Stereoscopic System) is an array of four very-high energy (VHE) gamma-ray telescopes located in Namibia. These telescopes use the atmospheric Cherenkov imaging technique to detect gamma-rays between 100 GeV and a few tens of TeV. The H.E.S.S. cameras, each composed of 960 photomultiplier tubes and a fast electronics, need an accurate calibration of the shower to electronic signal conversion. A spurious capacitive coupling between the photomultiplier tubes and the data acquisition system (the common modes) was revealed and corrected during this thesis, resulting in data of better quality. H.E.S.S. is ideally located to observe the inner regions of the Galactic plane. Hence, the Galactic Plane Survey has been one of the primary goal since the beginning of the array operation in 2004 and led to unveiling the diversity of the VHE gamma-ray sources. This thesis presents the search for VHE gamma-ray sources in the inner regions of the Galactic plane using the most sensitive semi-analytical model based analysis currently available. A search for transient sources was also performed for these regions using powerful methods based on the time difference between consecutive events. These methods have been precisely characterized by simulation and didn't lead to the detection of significant variable sources. The very-high energy gamma-ray emission from the W49 region and the supernova remnant W49B in particular has been revealed during this thesis. The analysis of this region and the implications of this discovery are described in detail in this manuscript. (author)

  3. Integração regional e constitucionalismo: análise do Tratado de Lisboa e estudo comparativo das perspectivas para o Mercosul

    OpenAIRE

    Mineiro de Aguiar Barbosa Pereira, Amanda

    2010-01-01

    O presente trabalho oferece uma perspectiva interdisciplinar, abordando temas do direito constitucional, do direito internacional e das ciências econômicas, sendo o objeto desta pesquisa o estudo do desenvolvimento do direito constitucional comum nos processos de integração regional europeu e mercosulino. A partir desse tema, abordar-se-á a tese do Estado constitucional cooperativo e do direito constitucional comum como respostas ao enfraquecimento do Estado-nação tradicional. Tal análise per...

  4. Hepatitis E in liver transplant recipients in the Rhône-Alpes region in France.

    Science.gov (United States)

    Buffaz, C; Scholtes, C; Dron, A-G; Chevallier-Queyron, P; Ritter, J; André, P; Ramière, C

    2014-06-01

    In developed countries, hepatitis E virus (HEV) is considered an emerging pathogen, but prevalence seems highly variable according to previous European studies. As HEV can lead to chronic infections in immunosuppressed patients, it is thus essential to evaluate the prevalence and incidence of this infection. We determined retrospectively, in a cohort of 206 pediatric and adult liver transplant recipients from the Rhône-Alpes region in France, pre-transplant anti-HEV-IgG prevalence and incidence of HEV infections during post-transplant follow-up (HEV IgG and IgM ± HEV-RNA). Transplantations were carried out between 2005 and 2012 and mean post-transplant follow-up was 32.8 months. Global pre-transplant prevalence of anti-HEV IgG was 29%, increasing regularly with age from 7% for children under 15 to 49% for patients older than 60. From the 142 seronegative patients before transplant, 11 seroconversions (7.7%) were observed during follow-up (incidence of 2.83 cases per 100 person-years). HEV RNA-tested at transaminases peak or randomly-was detected in only one case of seroconversion. For at least 2 HEV-seropositive patients, who had negative RNAemia before transplantation, viral RNA was detected chronically during follow-up, suggesting reinfection with HEV. Acute infections were largely more frequent than chronic infections and were asymptomatic or misdiagnosed, suggesting that liver transplant patients may not be particularly prone to developing severe HEV hepatitis. In addition, the presence of IgG anti-HEV may not protect against re-infection. Serological testing, therefore, appears to be of limited interest for the diagnosis of HEV infections in liver transplant recipients.

  5. The potential of e-ticketing for public transport planning: the Piedmont region case study

    Energy Technology Data Exchange (ETDEWEB)

    Arnone, M.

    2016-07-01

    In the Piedmont region (Italy) the electronic ticketing system called BIP, is currently active across much of its territory, and thedata collected in the Province of Cuneo since the full activation of the system (2014) provide today a sound source ofinformation. Two different travel documents are available, travel passes and pay-per-use, with different validation rules: check-inonly for travel passes and check-in and check-out for pay-per-use. Data produced by this electronic ticketing system employingsmart cards allow to perform a detailed analysis of each user’s behaviour, and calculate time and space distributions of eachpassenger trip. In detail, data originating from smart card transactions allow to trace back the trip chains, establish journey originsand destinations, and produce a “travel diary” for each passenger. Based on this data, performance indicators (i.e. load factor) aswell as user mobility patterns and origin-destination matrices can be calculated in an automated and reliable way. This articlepresents a methodology for assessing the quality of the data collected when information about boarding and alighting stops isavailable from the (on board) validation system. It also presents an algorithm to assign a destination for each trip where only theboarding information is available. In the case study of the Province of Cuneo, it was found that 91% of the pay-per-use journeydata are reliable and can be used for further analysis, whereas with the use of the proposed algorithm it was possible to estimatethe destinations for 82% of the travel pass trips. (Author)

  6. Prevalence of Hepatitis A Virus and Hepatitis E Virus in Western Thar Region

    Directory of Open Access Journals (Sweden)

    Prabhat Kiran Khatri

    2017-10-01

    Full Text Available Introduction: Hepatitis A Virus (HAV and Hepatitis E Virus (HEV pose major health problems in India. Both viruses are enterically transmitted, resulting in Acute Viral Hepatitis (AVH in developing countries. This study was done to determine prevalence of HAV and HEV and their co-infection in patients presenting with AVH in a tertiary care hospital. Aim: To determine the prevalence of HAV and HEV and their co-infection among patients attending a Tertiary Care Hospital in Jodhpur presenting with symptoms of acute hepatitis. Materials and Methods: A cross-sectional study of one year duration was conducted in the Department of Microbiology, Dr S.N. Medical College, Jodhpur. A non random sampling of 174 patients presenting with AVH was considered in the study. On the basis of history, serum samples were analyzed for IgM anti-HAV and IgM anti-HEV for the detection of HAV and HEV, respectively using commercially available ELISA kits. Data collected was analysed by using Statistical Package for the Social Sciences (SPSS version 11 and p-value <0.05 was considered significant. Results: The seroprevalence of HAV and HEV positive patients were 13.79% and 4.02%, respectively. The seroprevalence of both HAV and HEV in patients with AVH was 1.15%. The prevalence of HAV and HEV among males (58.3% and 41.6% was higher than in females (7.97% and 14.28%. Conclusion: The prevalence of HAV is higher than that of HEV but screening of HEV should be done as there are cases of coinfections. In this region of country, these data will play a role in planning of vaccination strategies and for better sanitation programme in future.

  7. Road Safety in Puglia Region La sicurezza stradale in Puglia: stato di fatto e ipotesi di intervento

    Directory of Open Access Journals (Sweden)

    Pierpaolo Bonerba

    2009-07-01

    association towards a safer and sustainable mobility. In addition, the enhancement of technical structures in charge of traffic and safety has been achieved. The expected results concern: – improvement of cooperation between all actors involved; – improvement of a local integrated culture about road safety; – availability of a powerful analysis tool and a Monitoring Centre; – development of some operational plans to improve safety and reduce crashes risks in the most critical points. – report progress in implementing the road safety strategy directed at reducing the number of accidents and casualties; – report the effectiveness of casualty reduction measures. – report on progress with road safety partnerships.L’articolo, partendo da una descrizione delle attività e delle principali funzioni del Centro Regionale di Monitoraggio della Sicurezza Stradale CReMSS della regione Puglia, vuole fornire un quadro sullo stato della sicurezza della rete stradale pugliese. In particolare lo studio vuole evidenziare le criticità e i punti di forza del caso della Puglia, mettendo in evidenza il sistema di interventi messi in atto e programmati. Il CReMSS, istituito con la legge regionale 18/2004, rappresenta uno strumento di raccolta e di analisi dei dati sull’incidentalità al fine di indirizzare le politiche e gli interventi in materia di sicurezza stradale, così come previsto nel Piano Nazionale della Sicurezza Stradale (PNSS legge 144/99. Le azioni del centro sono prevalentemente orientate al coordinamento e al raccordo con altri centri di monitoraggio (comunali, provinciali e nazionali in modo da assicurare un’integrazione delle basi conoscitive e valutative del fenomeno incidentalità viaria e con tutti gli enti, le scuole di ogni ordine grado, e le realtà del privato sociale per diffondere i saperi e condividere le buone pratiche in materia di sicurezza stradale.

  8. Remote sensing of auroral E region plasma structures by radio, radar, and UV techniques at solar minimum

    International Nuclear Information System (INIS)

    Basu, S.; Valladares, C.E.; Basu, S.; Eastes, R.; Huffman, R.E.; Daniell, R.E.; Chaturvedi, P.K.; Livingston, R.C.

    1993-01-01

    The unique capability of the Polar BEAR satellite to simultaneously image auroral luminosities at multiple ultraviolet (UV) wavelengths and to remote sense large-scale (hundreds to tens of kilometers) and small-scale (kilometers to hundreds of meters) plasma density structures with its multifrequency beacon package is utilized to probe the auroral E region in the vicinity of the incoherent scatter radar (ISR) facility near Sondrestrom. In particular, we present coordinated observations on two nights obtained during the sunspot minimum (sunspot number < 10) January-February 1987 period when good spatial and temporal conjunction was obtained between Polar BEAR overflights and Sondrestrom ISR measurements. With careful coordinated observations we were able to confirm that the energetic particle precipitation responsible for the UV emissions causes the electron density increases in the E region. The integrations up to the topside of these ISR electron density profiles were consistent with the total electron content (TEC) measured by the Polar BEAR satellite. An electron transport model was utilized to determine quantitatively the electron density profiles which could be produced by the particle precipitation, which also produced multiple UV emissions measured by the imager; these profiles were found to be in good agreement with the observed ISR profiles in the E region. This outer scale size is also consistent with the measured phase to amplitude scintillation ratio. An estimate of the linear growth rate of the gradient-drift instability in the E region shows that these plasma density irregularities could have been generated by this process. The mutual consistency of these different sets of measurements provides confidence in the ability of the different techniques to remote sense large- and small-scale plasma density structures in the E region at least during sunspot minimum when the convection-dominated high-latitude F region is fairly weak. 56 refs., 16 figs

  9. Functional analysis of the C-terminal region of human adenovirus E1A reveals a misidentified nuclear localization signal

    Energy Technology Data Exchange (ETDEWEB)

    Cohen, Michael J.; King, Cason R.; Dikeakos, Jimmy D. [Department of Microbiology and Immunology, The University of Western Ontario, A4-833 London Regional Cancer Centre, 800 Commissioners Road E., London, Ontario, N6A 4L6 Canada (Canada); Mymryk, Joe S., E-mail: jmymryk@uwo.ca [Department of Microbiology and Immunology, The University of Western Ontario, A4-833 London Regional Cancer Centre, 800 Commissioners Road E., London, Ontario, N6A 4L6 Canada (Canada); Department of Oncology, The University of Western Ontario, London Regional Cancer Centre, Ontario (Canada)

    2014-11-15

    The immortalizing function of the human adenovirus 5 E1A oncoprotein requires efficient localization to the nucleus. In 1987, a consensus monopartite nuclear localization sequence (NLS) was identified at the C-terminus of E1A. Since that time, various experiments have suggested that other regions of E1A influence nuclear import. In addition, a novel bipartite NLS was recently predicted at the C-terminal region of E1A in silico. In this study, we used immunofluorescence microscopy and co-immunoprecipitation analysis with importin-α to verify that full nuclear localization of E1A requires the well characterized NLS spanning residues 285–289, as well as a second basic patch situated between residues 258 and 263 ({sup 258}RVGGRRQAVECIEDLLNEPGQPLDLSCKRPRP{sup 289}). Thus, the originally described NLS located at the C-terminus of E1A is actually a bipartite signal, which had been misidentified in the existing literature as a monopartite signal, altering our understanding of one of the oldest documented NLSs. - Highlights: • Human adenovirus E1A is localized to the nucleus. • The C-terminus of E1A contains a bipartite nuclear localization signal (NLS). • This signal was previously misidentified to be a monopartite NLS. • Key basic amino acid residues within this sequence are highly conserved.

  10. Functional analysis of the C-terminal region of human adenovirus E1A reveals a misidentified nuclear localization signal

    International Nuclear Information System (INIS)

    Cohen, Michael J.; King, Cason R.; Dikeakos, Jimmy D.; Mymryk, Joe S.

    2014-01-01

    The immortalizing function of the human adenovirus 5 E1A oncoprotein requires efficient localization to the nucleus. In 1987, a consensus monopartite nuclear localization sequence (NLS) was identified at the C-terminus of E1A. Since that time, various experiments have suggested that other regions of E1A influence nuclear import. In addition, a novel bipartite NLS was recently predicted at the C-terminal region of E1A in silico. In this study, we used immunofluorescence microscopy and co-immunoprecipitation analysis with importin-α to verify that full nuclear localization of E1A requires the well characterized NLS spanning residues 285–289, as well as a second basic patch situated between residues 258 and 263 ( 258 RVGGRRQAVECIEDLLNEPGQPLDLSCKRPRP 289 ). Thus, the originally described NLS located at the C-terminus of E1A is actually a bipartite signal, which had been misidentified in the existing literature as a monopartite signal, altering our understanding of one of the oldest documented NLSs. - Highlights: • Human adenovirus E1A is localized to the nucleus. • The C-terminus of E1A contains a bipartite nuclear localization signal (NLS). • This signal was previously misidentified to be a monopartite NLS. • Key basic amino acid residues within this sequence are highly conserved

  11. Seasonal variation of low-latitude E-region plasma irregularities studied using Gadanki radar and ionosonde

    Directory of Open Access Journals (Sweden)

    D. V. Phanikumar

    2008-07-01

    Full Text Available In this paper, we present seasonal variation of E region field-aligned irregularities (FAIs observed using the Gadanki radar and compare them with the seasonal variation of Es observed from a nearby location SHAR. During daytime, FAIs occur maximum in summer and throughout the day, as compared to other seasons. During nighttime, FAIs occur equally in both summer and winter, and relatively less in equinoxes. Seasonal variations of Es (i.e. ftEs and fbEs show that the daytime activity is maximum in summer and the nighttime activity is maximum in equinoxes. No relation is found between FAIs occurrence/SNR and ftEs/fbEs. FAIs occurrence, however, is found to be related well with (ftEs−fbEs. This aspect is discussed in the light of the present understanding of the mid-latitude Es-FAIs relationship. The seasonal variations of FAIs observed at Gadanki are compared in detail with those of Piura, which show a significant difference in the daytime observations. The observed difference has been discussed considering the factors governing the generation of FAIs.

  12. Angular analysis of the $B^0 \\rightarrow K^{*0} e^+ e^-$ decay in the low-$q^2$ region

    CERN Document Server

    Aaij, Roel; Adinolfi, Marco; Affolder, Anthony; Ajaltouni, Ziad; Akar, Simon; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Anderson, Jonathan; Andreassen, Rolf; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Aquines Gutierrez, Osvaldo; Archilli, Flavio; Artamonov, Alexander; Artuso, Marina; Aslanides, Elie; Auriemma, Giulio; Baalouch, Marouen; Bachmann, Sebastian; Back, John; Badalov, Alexey; Baesso, Clarissa; Baldini, Wander; Barlow, Roger; Barschel, Colin; Barsuk, Sergey; Barter, William; Batozskaya, Varvara; Battista, Vincenzo; Bay, Aurelio; Beaucourt, Leo; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Belogurov, Sergey; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Benton, Jack; Berezhnoy, Alexander; Bernet, Roland; Bertolin, Alessandro; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bien, Alexander; Bifani, Simone; Bird, Thomas; Bizzeti, Andrea; Blake, Thomas; Blanc, Frédéric; Blouw, Johan; Blusk, Steven; Bocci, Valerio; Bondar, Alexander; Bondar, Nikolay; Bonivento, Walter; Borghi, Silvia; Borgia, Alessandra; Borsato, Martino; Bowcock, Themistocles; Bowen, Espen Eie; Bozzi, Concezio; Brett, David; Britsch, Markward; Britton, Thomas; Brodzicka, Jolanta; Brook, Nicholas; Bursche, Albert; Buytaert, Jan; Cadeddu, Sandro; Calabrese, Roberto; Calvi, Marta; Calvo Gomez, Miriam; Campana, Pierluigi; Campora Perez, Daniel; Capriotti, Lorenzo; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casanova Mohr, Raimon; Casse, Gianluigi; Cassina, Lorenzo; Castillo Garcia, Lucia; Cattaneo, Marco; Cauet, Christophe; Cenci, Riccardo; Charles, Matthew; Charpentier, Philippe; Chefdeville, Maximilien; Chen, Shanzhen; Cheung, Shu-Faye; Chiapolini, Nicola; Chrzaszcz, Marcin; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Cogan, Julien; Cogneras, Eric; Cogoni, Violetta; Cojocariu, Lucian; Collazuol, Gianmaria; Collins, Paula; Comerma-Montells, Albert; Contu, Andrea; Cook, Andrew; Coombes, Matthew; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Counts, Ian; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Crocombe, Andrew Christopher; Cruz Torres, Melissa Maria; Cunliffe, Samuel; Currie, Robert; D'Ambrosio, Carmelo; Dalseno, Jeremy; David, Pascal; David, Pieter; Davis, Adam; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Silva, Weeraddana; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Deckenhoff, Mirko; Del Buono, Luigi; Déléage, Nicolas; Derkach, Denis; Deschamps, Olivier; Dettori, Francesco; Dey, Biplab; Di Canto, Angelo; Di Domenico, Antonio; Di Ruscio, Francesco; Dijkstra, Hans; Donleavy, Stephanie; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Dossett, David; Dovbnya, Anatoliy; Dreimanis, Karlis; Dujany, Giulio; Dupertuis, Frederic; Durante, Paolo; Dzhelyadin, Rustem; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; El Rifai, Ibrahim; Elsasser, Christian; Ely, Scott; Esen, Sevda; Evans, Hannah Mary; Evans, Timothy; Falabella, Antonio; Färber, Christian; Farinelli, Chiara; Farley, Nathanael; Farry, Stephen; Fay, Robert; Ferguson, Dianne; Fernandez Albor, Victor; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fiore, Marco; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fol, Philip; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Francisco, Oscar; Frank, Markus; Frei, Christoph; Frosini, Maddalena; Fu, Jinlin; Furfaro, Emiliano; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; García Pardiñas, Julián; Garofoli, Justin; Garra Tico, Jordi; Garrido, Lluis; Gascon, David; Gaspar, Clara; Gastaldi, Ugo; Gauld, Rhorry; Gavardi, Laura; Gazzoni, Giulio; Geraci, Angelo; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Ghez, Philippe; Gianelle, Alessio; Gianì, Sebastiana; Gibson, Valerie; Giubega, Lavinia-Helena; Gligorov, V.V.; Göbel, Carla; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gotti, Claudio; Grabalosa Gándara, Marc; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graverini, Elena; Graziani, Giacomo; Grecu, Alexandru; Greening, Edward; Gregson, Sam; Griffith, Peter; Grillo, Lucia; Grünberg, Oliver; Gui, Bin; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hall, Samuel; Hamilton, Brian; Hampson, Thomas; Han, Xiaoxue; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Jonathan; He, Jibo; Head, Timothy; Heijne, Veerle; Hennessy, Karol; Henrard, Pierre; Henry, Louis; Hernando Morata, Jose Angel; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hill, Donal; Hoballah, Mostafa; Hombach, Christoph; Hulsbergen, Wouter; Hussain, Nazim; Hutchcroft, David; Hynds, Daniel; Idzik, Marek; Ilten, Philip; Jacobsson, Richard; Jaeger, Andreas; Jalocha, Pawel; Jans, Eddy; Jawahery, Abolhassan; Jing, Fanfan; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Kanso, Walaa; Karacson, Matthias; Karbach, Moritz; Karodia, Sarah; Kelsey, Matthew; Kenyon, Ian; Kenzie, Matthew; Ketel, Tjeerd; Khanji, Basem; Khurewathanakul, Chitsanu; Klaver, Suzanne; Klimaszewski, Konrad; Kochebina, Olga; Kolpin, Michael; Komarov, Ilya; Koopman, Rose; Koppenburg, Patrick; Korolev, Mikhail; Kravchuk, Leonid; Kreplin, Katharina; Kreps, Michal; Krocker, Georg; Krokovny, Pavel; Kruse, Florian; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kurek, Krzysztof; Kvaratskheliya, Tengiz; La Thi, Viet Nga; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lambert, Dean; Lambert, Robert W; Lanfranchi, Gaia; Langenbruch, Christoph; Langhans, Benedikt; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; van Leerdam, Jeroen; Lees, Jean-Pierre; Lefèvre, Regis; Leflat, Alexander; Lefrançois, Jacques; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Yiming; Likhomanenko, Tatiana; Liles, Myfanwy; Lindner, Rolf; Linn, Christian; Lionetto, Federica; Liu, Bo; Lohn, Stefan; Longstaff, Iain; Lopes, Jose; Lowdon, Peter; Lucchesi, Donatella; Luo, Haofei; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Machefert, Frederic; Machikhiliyan, Irina V; Maciuc, Florin; Maev, Oleg; Malde, Sneha; Malinin, Alexander; Manca, Giulia; Mancinelli, Giampiero; Manning, Peter Michael; Mapelli, Alessandro; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marino, Pietro; Märki, Raphael; Marks, Jörg; Martellotti, Giuseppe; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Martins Tostes, Danielle; Massafferri, André; Matev, Rosen; Mathe, Zoltan; Matteuzzi, Clara; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McCarthy, James; McNab, Andrew; McNulty, Ronan; McSkelly, Ben; Meadows, Brian; Meier, Frank; Meissner, Marco; Merk, Marcel; Milanes, Diego Alejandro; Minard, Marie-Noelle; Moggi, Niccolò; Molina Rodriguez, Josue; Monteil, Stephane; Morandin, Mauro; Morawski, Piotr; Mordà, Alessandro; Morello, Michael Joseph; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Müller, Katharina; Mussini, Manuel; Muster, Bastien; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Anh Duc; Nguyen, Thi-Dung; Nguyen-Mau, Chung; Nicol, Michelle; Niess, Valentin; Niet, Ramon; Nikitin, Nikolay; Nikodem, Thomas; Novoselov, Alexey; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Ogilvy, Stephen; Okhrimenko, Oleksandr; Oldeman, Rudolf; Onderwater, Gerco; Orlandea, Marius; Osorio Rodrigues, Bruno; Otalora Goicochea, Juan Martin; Otto, Adam; Owen, Patrick; Oyanguren, Maria Arantza; Pal, Bilas Kanti; Palano, Antimo; Palombo, Fernando; Palutan, Matteo; Panman, Jacob; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parkes, Christopher; Parkinson, Christopher John; Passaleva, Giovanni; Patel, Girish; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Penso, Gianni; Pepe Altarelli, Monica; Perazzini, Stefano; Perret, Pascal; Pescatore, Luca; Pesen, Erhan; Petridis, Konstantin; Petrolini, Alessandro; Picatoste Olloqui, Eduardo; Pietrzyk, Boleslaw; Pilař, Tomas; Pinci, Davide; Pistone, Alessandro; Playfer, Stephen; Plo Casasus, Maximo; Polci, Francesco; Poluektov, Anton; Polyakov, Ivan; Polycarpo, Erica; Popov, Alexander; Popov, Dmitry; Popovici, Bogdan; Potterat, Cédric; Price, Eugenia; Price, Joseph David; Prisciandaro, Jessica; Pritchard, Adrian; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Punzi, Giovanni; Qian, Wenbin; Quagliani, Renato; Rachwal, Bartolomiej; Rademacker, Jonas; Rakotomiaramanana, Barinjaka; Rama, Matteo; Rangel, Murilo; Raniuk, Iurii; Rauschmayr, Nathalie; Raven, Gerhard; Redi, Federico; Reichert, Stefanie; Reid, Matthew; dos Reis, Alberto; Ricciardi, Stefania; Richards, Sophie; Rihl, Mariana; Rinnert, Kurt; Rives Molina, Vincente; Robbe, Patrick; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Perez, Pablo; Roiser, Stefan; Romanovsky, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rouvinet, Julien; Ruf, Thomas; Ruiz, Hugo; Ruiz Valls, Pablo; Saborido Silva, Juan Jose; Sagidova, Naylya; Sail, Paul; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santovetti, Emanuele; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saunders, Daniel Martin; Savrina, Darya; Schiller, Manuel; Schindler, Heinrich; Schlupp, Maximilian; Schmelling, Michael; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sepp, Indrek; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seyfert, Paul; Shapkin, Mikhail; Shapoval, Illya; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shires, Alexander; Silva Coutinho, Rafael; Simi, Gabriele; Sirendi, Marek; Skidmore, Nicola; Skillicorn, Ian; Skwarnicki, Tomasz; Smith, Anthony; Smith, Edmund; Smith, Eluned; Smith, Jackson; Smith, Mark; Snoek, Hella; Sokoloff, Michael; Soler, Paul; Soomro, Fatima; Souza, Daniel; Souza De Paula, Bruno; Spaan, Bernhard; Spradlin, Patrick; Sridharan, Srikanth; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Steinkamp, Olaf; Stenyakin, Oleg; Sterpka, Christopher Francis; Stevenson, Scott; Stoica, Sabin; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Straticiuc, Mihai; Straumann, Ulrich; Stroili, Roberto; Sun, Liang; Sutcliffe, William; Swientek, Krzysztof; Swientek, Stefan; Syropoulos, Vasileios; Szczekowski, Marek; Szczypka, Paul; Szumlak, Tomasz; T'Jampens, Stephane; Teklishyn, Maksym; Tellarini, Giulia; Teubert, Frederic; Thomas, Christopher; Thomas, Eric; van Tilburg, Jeroen; Tisserand, Vincent; Tobin, Mark; Todd, Jacob; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Topp-Joergensen, Stig; Torr, Nicholas; Tournefier, Edwige; Tourneur, Stephane; Trabelsi, Karim; Tran, Minh Tâm; Tresch, Marco; Trisovic, Ana; Tsaregorodtsev, Andrei; Tsopelas, Panagiotis; Tuning, Niels; Ubeda Garcia, Mario; Ukleja, Artur; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagnoni, Vincenzo; Valenti, Giovanni; Vallier, Alexis; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vázquez Sierra, Carlos; Vecchi, Stefania; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Vesterinen, Mika; Viana Barbosa, Joao Vitor; Viaud, Benoit; Vieira, Daniel; Vieites Diaz, Maria; Vilasis-Cardona, Xavier; Vollhardt, Achim; Volyanskyy, Dmytro; Voong, David; Vorobyev, Alexey; Vorobyev, Vitaly; Voß, Christian; de Vries, Jacco; Waldi, Roland; Wallace, Charlotte; Wallace, Ronan; Walsh, John; Wandernoth, Sebastian; Wang, Jianchun; Ward, David; Watson, Nigel; Websdale, David; Whitehead, Mark; Wiedner, Dirk; Wilkinson, Guy; Wilkinson, Michael; Williams, Matthew; Williams, Mike; Wilschut, Hans; Wilson, Fergus; Wimberley, Jack; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wright, Simon; Wyllie, Kenneth; Xie, Yuehong; Xing, Zhou; Xu, Zhirui; Yang, Zhenwei; Yuan, Xuhao; Yushchenko, Oleg; Zangoli, Maria; Zavertyaev, Mikhail; Zhang, Liming; Zhang, Wen Chao; Zhang, Yanxi; Zhelezov, Alexey; Zhokhov, Anatoly; Zhong, Liang

    2015-04-14

    An angular analysis of the $B^0 \\rightarrow K^{*0} e^+ e^-$ decay is performed using a data sample, corresponding to an integrated luminosity of 3.0 ${\\mbox{fb}^{-1}}$, collected by the LHCb experiment in $pp$ collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared ($q^2$) interval between 0.002 and 1.120${\\mathrm{\\,Ge\\kern -0.1em V^2\\!/}c^4}$. The angular observables $F_{\\mathrm{L}}$ and $A_{\\mathrm{T}}^{\\mathrm{Re}}$ which are related to the $K^{*0}$ polarisation and to the lepton forward-backward asymmetry, are measured to be $F_{\\mathrm{L}}= 0.16 \\pm 0.06 \\pm0.03$ and $A_{\\mathrm{T}}^{\\mathrm{Re}} = 0.10 \\pm 0.18 \\pm 0.05$, where the first uncertainty is statistical and the second systematic. The angular observables $A_{\\mathrm{T}}^{(2)}$ and $A_{\\mathrm{T}}^{\\mathrm{Im}}$ which are sensitive to the photon polarisation in this $q^2$ range, are found to be $A_{\\mathrm{T}}^{(2)} = -0.23 \\pm 0.23 \\pm 0.05$ a...

  13. A relação inseparável entre o Regional e o Nacional: Monteiro Lobato e a Paulistanidade

    Directory of Open Access Journals (Sweden)

    Danyllo Di Giorgio Martins da Mota

    2012-12-01

    Full Text Available Esse artigo tem como objetivo discutir a definição conceitual da idéia de Paulistanidade e sua presença na obra de Monteiro Lobato durante a década de 1920, sobretudo no livro Mr. Slang e o Brasil de 1927. A valorização do estado de São Paulo como lugar de modernidade e modernização se relacionou, a partir do final do século XIX, com a construção de imagens do estado paulista como símbolo a ser seguido pelo Brasil. Nesses debates, o trabalho de Monteiro Lobato acaba por expor a relação indissociável entre as esferas regional e nacional.

  14. Globalização e desenvolvimento regional na Tríplice Fronteira

    Directory of Open Access Journals (Sweden)

    Eric Gustavo Cardin

    2009-01-01

    Full Text Available This paper discusses the relationship between the process of globalization and the opportunities for regional development. In order to do that, it theoretically discusses the concepts of globalization, governance and paradiplomacia, noting some of the conflicts and contradictions existing in some of the discussions between skeptical and globalistas. The article also presents empirical considerations by observing the socioeconomic development of the region known as the Triple Frontier (Brazil, Paraguay and Argentina, exploring the interdependence relationship and questioning the contributions that the conceptual discussions bring for the strengthening of reflections referring to local and regional growth.

  15. Possible experimental studies of the t anti t threshold region at 250--500 GeV e+e- collider

    International Nuclear Information System (INIS)

    Komamiya, Sachio.

    1991-01-01

    A possible measurement of the top quark mass by an energy scan of the t anti t threshold region at e + e - colliders of √s = 250--500 GeV is discussed. With an integrated luminosity of 1 fb -1 devoted to the energy scan, a top quark mass of about 150 GeV can be determined with an accuracy of ∼0.3 GeV, with a comparable systematic uncertainty arising from the few % errors in the α s measurement at LEP-I. The possibilities of studying Γ t and Higgs boson effects are also discussed. 10 refs., 12 figs., 4 tabs

  16. Desempenho organizacional e arranjo federativo: o slack da Sudene e o colapso na gest??o da pol??tica de planejamento regional

    OpenAIRE

    Fitipaldi, ??talo

    2009-01-01

    Este artigo procura explicar as raz??es do colapso na gest??o do sistema de planejamento regional no Brasil, debru??ando-se sobre a extin????o da Sudene no final da d??cada de 1990, como estudo de caso. Para tanto, utiliza-se o modelo de sa??da, voz e lealdade de Hirschman, para destacar o funcionamento dos mecanismos promotores do slack organizacional nessa ag??ncia de governo, e sua subsequente extin????o. Assim, sustenta-se o argumento de que a implementa????o de modelo federativo fortemen...

  17. Poisson-like shape and shoulder structure of hadron multiplicity distributions in e+e- annihilation at Z0 energy region

    International Nuclear Information System (INIS)

    Xie Yigang; Chai Yong

    1994-01-01

    The charged multiplicity distributions of hadron final states in the e + e - annihilation at the 91.2 GeV Z 0 energy region are fitted with Poisson shape in different rapidity windows for double and single hemisphere. The multiplicities which are in Poisson-like shapes can be got according to the parameter /D and fitting qualities are compared with the results derived from the relevant theoretical models. The relationship between the Poisson-like shape and KNO scaling is discussed. The connection between the parameters expressing the deviation from the Poisson shape and non-independent particle emission and multiplicity correlation strength is analyzed. The 'shoulder structure' is observed in the central rapidity region and analyzed with multi-jets by using the JADE jet analysis algorithm

  18. HLA-E regulatory and coding region variability and haplotypes in a Brazilian population sample.

    Science.gov (United States)

    Ramalho, Jaqueline; Veiga-Castelli, Luciana C; Donadi, Eduardo A; Mendes-Junior, Celso T; Castelli, Erick C

    2017-11-01

    The HLA-E gene is characterized by low but wide expression on different tissues. HLA-E is considered a conserved gene, being one of the least polymorphic class I HLA genes. The HLA-E molecule interacts with Natural Killer cell receptors and T lymphocytes receptors, and might activate or inhibit immune responses depending on the peptide associated with HLA-E and with which receptors HLA-E interacts to. Variable sites within the HLA-E regulatory and coding segments may influence the gene function by modifying its expression pattern or encoded molecule, thus, influencing its interaction with receptors and the peptide. Here we propose an approach to evaluate the gene structure, haplotype pattern and the complete HLA-E variability, including regulatory (promoter and 3'UTR) and coding segments (with introns), by using massively parallel sequencing. We investigated the variability of 420 samples from a very admixed population such as Brazilians by using this approach. Considering a segment of about 7kb, 63 variable sites were detected, arranged into 75 extended haplotypes. We detected 37 different promoter sequences (but few frequent ones), 27 different coding sequences (15 representing new HLA-E alleles) and 12 haplotypes at the 3'UTR segment, two of them presenting a summed frequency of 90%. Despite the number of coding alleles, they encode mainly two different full-length molecules, known as E*01:01 and E*01:03, which corresponds to about 90% of all. In addition, differently from what has been previously observed for other non classical HLA genes, the relationship among the HLA-E promoter, coding and 3'UTR haplotypes is not straightforward because the same promoter and 3'UTR haplotypes were many times associated with different HLA-E coding haplotypes. This data reinforces the presence of only two main full-length HLA-E molecules encoded by the many HLA-E alleles detected in our population sample. In addition, this data does indicate that the distal HLA-E promoter is by

  19. Origin of enhanced vibrational excitation in N2 by electron impact in the 15--35 eV region

    International Nuclear Information System (INIS)

    Dehmer, J.L.; Siegel, J.; Welch, J.; Dill, D.

    1980-01-01

    The authors calculate the integrated vibrational excitation cross section for e-N 2 scattering in the interval 0 --50 eV using the continuum multiple-scattering model with the Hara exchange approximation. Resonant enhancement is observed at 2.4 eV owing to the well-known π/sub g/ shape resonance. In addition, however, enhanced vibrational excitation is found centered at approx.26 eV, arising from a broad shape resonance in the sigma/sub u/ channel. The authors propose this one-electron feature as the main source of the enhanced vibrational excitation observed by Pavlovic et al. in the 15--35 eV region

  20. Low energy E0 transitions in odd-mass nuclei of the neutron deficient 180 < A < 200 region

    International Nuclear Information System (INIS)

    Zganjar, E.F.; Kortelahti, M.O.; Wood, J.L.; Papanicolopulos, C.D.

    1987-01-01

    The region of neutron-deficient nuclei near Z = 82 and N = 104 provides the most extensive example of low-energy shape coexistence anywhere on the mass surface. It is shown that E0 and E0 admixed transitions may be used as a fingerprint to identify shape coexistence in odd-mass nuclei. It is also shown that all the known cases of low energy E0 and E0 admixed transitions in odd-mass nuclei occur where equally low-lying O + states occur in neighboring even-even nuclei. A discussion of these and other relevant data as well as suggestions for new studies which may help to clarify and, more importantly, quantify the connection between E0 transitions and shape coexistence are presented. 60 refs., 7 figs., 4 tabs

  1. Sequence evolution of the hypervariable region in the putative envelope region E2/NS1 of hepatitis C virus is correlated with specific humoral immune responses.

    OpenAIRE

    van Doorn, L J; Capriles, I; Maertens, G; DeLeys, R; Murray, K; Kos, T; Schellekens, H; Quint, W

    1995-01-01

    Sequence evolution of the hypervariable region 1 (HVR1) in the N terminus of E2/NS1 of hepatitis C virus (HCV) was studied retrospectively in six chimpanzees inoculated with the same genotype 1b strain, containing a unique predominant HVR1 sequence. Immediately after inoculation, all animals contained the same HVR predominant sequence. Two animals developed an acute self-limiting infection. Anti-HVR1 immunoglobulin G (IgG) was produced 40 to 60 days after inoculation and rapidly disappeared a...

  2. As assimetrias entre as políticas setoriais e a política de planejamento regional no Brasil

    Directory of Open Access Journals (Sweden)

    João Mendes da Rocha Neto

    2011-12-01

    Full Text Available O modo de conduzir a formulação das políticas de desenvolvimento regional tem se constituído em ampla arena de embates acadêmicos e técnicos e levado a reflexões sobre os rumos das múltiplas políticas que acompanham esse processo de planejamento regional. Isso, em parte, decorre do processo de globalização e das políticas neoliberais que o acompanham, as quais possuem um forte apelo à competitividade. Essa estratégia de buscar espaços "privilegiados" se fez presente de uma forma intensa em alguns setores produtivos, que, ao usar o espaço como mercadoria, utilizam seu conjunto de atributos (naturais e artificiais para realizarem-se e reproduzirem-se como parte do sistema. Assim, a proposta de estudo pretende responder a questão: em que medida as políticas públicas setoriais têm dialogado com as políticas de planejamento e desenvolvimento regional no âmbito do governo federal? No caso das políticas de planejamento regional, o recorte espacial é visto como um instrumento que, ao ser aplicado, pode se mostrar capaz de viabilizar a integração de ações multissetorializadas, o que em certa dimensão apontaria para uma maior eficiência do Estado na busca por restabelecer o equilíbrio esgarçado, tornando mais eficiente o planejamento.

  3. Simultaneous VHF radar backscatter and ionosonde observations of low-latitude E region

    Directory of Open Access Journals (Sweden)

    A. K. Patra

    2005-03-01

    Full Text Available The first results of simultaneous observations made on the low-latitude field-aligned irregularities (FAI using the MST radar located at Gadanki (13.5° N, 79.2° E, dip 12.5° and the Es parameters using an ionosonde at a nearby station Sriharikota (13.7° N, 80.1° E, dip 12.6° are presented. The observations show that while the height of the most intense radar echoes is below the virtual height of Es (h'Es during daytime, it is found to be either below or above during nighttime. The strength of the FAI is better correlated with the top penetration frequency (ftEs and the blanketing frequency (fbEs during the night (r=0.4 in both cases as compared to the day (r=0.35 and -0.04, respectively. Furthermore, the signal strength of FAI is reasonably correlated with (ftEs-fbEs during daytime (r=0.59 while very poorly correlated during nighttime (r=0.18. While the radar observations in general appear to have characteristics close to that of mid-latitudes, the relationship of these with the Es parameters are poorer than that of mid-latitudes. The observations reported here, nevertheless, are quite consistent with the expectations based on the gradient drift instability mechanism.

  4. Prevalência de sobrepeso e obesidade nas regiões Nordeste e Sudeste do Brasil Overweight and obesity prevalence in Northeast and Southeast Regions of Brazil

    Directory of Open Access Journals (Sweden)

    Marcelo Militão Abrantes

    2003-06-01

    Full Text Available OBJETIVO: Avaliar a prevalência de sobrepeso e obesidade em crianças, adolescentes, adultos e idosos brasileiros das regiões Nordeste e Sudeste; MÉTODOS: Avaliação antropométrica de 17.184 pessoas, estudadas na Pesquisa sobre Padrões de Vida (PPV realizada pelo IBGE em 1996/97, através do índice de massa corporal sendo usados como limite para sobrepeso e obesidade os valores propostos por Cole et al. por permitirem uma continuidade de critério de sobrepeso e obesidade na infância, adolescência e idade adulta. RESULTADOS: Predomínio do sexo feminino, 53,1%, na população estudada. A média de idade foi de 29 anos e 5 meses (desvio padrão de ± 20 anos, a mediana foi de 25 anos e 6 meses. A prevalência de sobrepeso foi de 10,8% entre crianças, 9,9% nos adolescentes e 28,3% entre adultos e a de obesidade foi 7,3%, 1,8% e 9,7%, respectivamente. Observado um aumento gradativo da prevalência de sobrepeso e obesidade desde a infância até a idade adulta, com declínio entre os idosos. CONCLUSÕES: Prevalência conjunta de sobrepeso e obesidade na população brasileira é maior no sexo feminino sendo que mais da metade das mulheres das regiões Nordeste e Sudeste do Brasil, com idade entre 50 e 69 anos, têm sobrepeso e/ou obesidade. A comparação de estudos de prevalência de sobrepeso e obesidade na infância e adolescência é dificultada pela escassez de estudos populacionais nacionais e diversidade de critérios utilizados na avaliação nutricional.OBJECTIVE: to evaluate the prevalence of overweight and obesity in children, adolescents, adults and elderlies from Northeast and Southeast regions of Brazil. METHODS: anthropometric evaluation of 17.184 people, studied in Life Pattern Research conducted by Brazilian Institute of Geographic and Statistics in 1996/97, by body mass index. Overweight and obesity definitions according to body mass index values proposed by Cole et al. which are related to adult definition. RESULTS: It

  5. New global electron density observations from GPS-RO in the D- and E-Region ionosphere

    Science.gov (United States)

    Wu, Dong L.

    2018-06-01

    A novel retrieval technique is developed for electron density (Ne) in the D- and E-region (80-120 km) using the high-quality 50-Hz GPS radio occultation (GPS-RO) phase measurements. The new algorithm assumes a slow, linear variation in the F-region background when the GPS-RO passes through the D- and E-region, and extracts the Ne profiles at 80-130 km from the phase advance signal caused by Ne. Unlike the conventional Abel function, the new approach produces a sharp Ne weighting function in the lower ionosphere, and the Ne retrievals are in good agreement with the IRI (International Reference Ionosphere) model in terms of monthly maps, zonal means and diurnal variations. The daytime GPS-RO Ne profiles can be well characterized by the α-Chapman function of three parameters (NmE, hmE and H), showing that the bottom of E-region is deepening and sharpening towards the summer pole. At high latitudes the monthly GPS-RO Ne maps at 80-120 km reveal clear enhancement in the auroral zones, more prominent at night, as a result of energetic electron precipitation (EEP) from the outer radiation belt. The D-/E-region auroral Ne is strongly correlated with Kp on a daily basis. The new Ne data allow further comprehensive analyses of the sporadic E (Es) phenomena in connection with the background Ne in the E-region. The layered (2-10 km) and fluctuated (Layer than Ne_Pert, are extracted with respect to the background Ne_Region on a profile-by-profile basis. The Ne_Layer component has a strong but highly-refined peak at ∼105 km, with an amplitude smaller than Ne_Region approximately by an order of magnitude. The Ne_Pert component, which was studied extensively in the past, is ∼2 orders of magnitude weaker than Ne_Layer. Both Ne_Layer and Ne_Pert are subject to significant diurnal and semidiurnal variations, showing downward progression with local time in amplitude. The 11-year solar cycle dominates the Ne interannual variations, showing larger Ne_Region and Ne_Layer but smaller

  6. Agropecuária brasileira: desempenho regional e determinantes de produtividade

    Directory of Open Access Journals (Sweden)

    João Felema

    2013-09-01

    Full Text Available Este estudo teve por objetivo medir a produtividade líquida do trabalho e da terra no Brasil, em seus estados e municípios, e identificar os fatores que exercem influência sobre estas produtividades, com base nos dados do Censo Agropecuário de 2006, do IBGE. Tais produtividades podem ser não uniformes na agropecuária brasileira, dado que apresentam comportamentos diferentes à estrutura produtiva e às características intrínsecas a cada região. Utilizaram-se modelos de regressão linear múltipla para identificar a influência de fatores de produção no desempenho da agropecuária do País. Como resultado, observou-se que os melhores índices quanto à produtividade do trabalho e da terra estão localizados principalmente nas regiões Sul e Sudeste, havendo concentração dos mais altos valores em apenas alguns municípios do País. Por fim, a análise geral das estimativas demonstrou que as variáveis "insumos agropecuários" e "mecanização" apresentaram participação positiva na agropecuária da maioria dos estados brasileiros.

  7. The role of vibrationally excited oxygen and nitrogen in the D and E regions of the ionosphere

    Directory of Open Access Journals (Sweden)

    A. V. Pavlov

    1994-08-01

    Full Text Available In this paper we present the results of a study of the effect of vibrationally excited oxygen, O*2, and nitrogen, N*2, on the electron density, Ne, and the electron temperature, Te, in the D and E regions. The sources of O*2 are O-atom recombination, the photodissociation of O3, and the reaction of O3 with O at D region altitudes. The first calculations of O*2( j number densities, Nj, are obtained by solving continuity equations for the models of harmonic and anharmonic oscillator energy levels, j=1-22. It is found that day time values of Nj are less than nighttime values. We also show that the photoionization of O*2 ( j ≥ 11 by Lα-radiation has no influence on the D region Ne. In the nighttime D region the photoionization O*2 ( j ≥ 11 by scattered Lα-radiation can be a new source of O+2. We show that the N*2 and O*2 de-excitation effect on the electron temperature is small in the E region of the ionosphere and cannot explain experimentally observed higher electron temperatures.

  8. Overcoming Interoperability Weaknesses in e-Government Processes: Organizing and Sharing Knowledge in Regional Development Programs Using Ontologies

    Science.gov (United States)

    Scorza, Francesco; Casas, Giuseppe Las; Murgante, Beniamino

    European Regional Policy produced several generations of programmes at both National and Regional levels. Such a complex framework tends to increase multi-level governance in the period 2007-2013, promoting a wider participation of stakeholders (including Public Administration, Local Communities, Enterprises, etc). This process has been usually accompanied by e-tools for the management of bottom-up processes, with several instances related to common problems of participation processes. Communication between "programmer" and categories of beneficiaries always presented weakness due to the ineffective system of management knowledge within the process. Relevant issues in the framework of regional development programmes are: Do stakeholders understand the meaning of general and sectoral policies? Are citizens aware of technical instruments implementing such policies? Are they conscious of ex-ante comprehensive context analysis and/or can they share possible future scenarios? A way to tackle these problems is the use of ontologies. In this work we present the structural elements of the ontology of regional development programmes analyzing major steps of the ontology design and nodal phases of the ontology building (i.e. consensus on relations and restrictions, switch from glossary to taxonomy). The result of such an application is an ontology of regional development containing more than one hundred classes.

  9. Oligopolios mixtos, privatización e integración regional

    Directory of Open Access Journals (Sweden)

    José Méndez Naya

    2008-01-01

    Full Text Available Partiendo de un modelo sencillo de oligopolio internacional mixto, en que los países pueden aplicar aranceles discriminatorios, se analizan los efectos en las variables relevantes derivados de los procesos de privatización y liberación regional de la economía. En concreto se justifica, desde un punto de vista teórico, la evidencia empírica que nos muestra que los procesos de liberación regional de la economía y la privatización de las empresas públicas son procesos complementarios.

  10. E-health: Determinants, opportunities, challenges and the way forward for countries in the WHO African Region

    Directory of Open Access Journals (Sweden)

    Gatwiri Doris

    2005-12-01

    Full Text Available Abstract Background The implementation of the 58th World Health Assembly resolution on e-health will pose a major challenge for the Member States of the World Health Organization (WHO African Region due to lack of information and communications technology (ICT and mass Internet connectivity, compounded by a paucity of ICT-related knowledge and skills. The key objectives of this article are to: (i explore the key determinants of personal computers (PCs, telephone mainline and cellular and Internet penetration/connectivity in the African Region; and (ii to propose actions needed to create an enabling environment for e-health services growth and utilization in the Region. Methods The effects of school enrolment, per capita income and governance variables on the number of PCs, telephone mainlines, cellular phone subscribers and Internet users were estimated using a double-log regression model and cross-sectional data on various Member States in the African Region. The analysis was based on 45 of the 46 countries that comprise the Region. The data were obtained from the United Nations Development Programme (UNDP, the World Bank and the International Telecommunications Union (ITU sources. Results There were a number of main findings: (i the adult literacy and total number of Internet users had a statistically significant (at 5% level in a t-distribution test positive effect on the number of PCs in a country; (ii the combined school enrolment rate and per capita income had a statistically significant direct effect on the number of telephone mainlines and cellular telephone subscribers; (iii the regulatory quality had statistically significant negative effect on the number of telephone mainlines; (iv similarly, the combined school enrolment ratio and the number of telephone mainlines had a statistically significant positive relationship with Internet usage; and (v there were major inequalities in ICT connectivity between upper-middle, lower-middle and

  11. Integração regional e investimento estrangeiro direto, à exemplo do Mercosul

    Directory of Open Access Journals (Sweden)

    Amanda do Valle Correa Ramos

    2015-12-01

    Full Text Available A globalização e o contexto histórico mundial do pós segunda guerra, são, dentre outras, as principais causas pelo surgimento do regionalismo, sequenciando o desenvolvimento do Direito Internacional, chegando-se assim ao Investimento Direto Estrangeiro. Nesse emaranhado de situações e fatores econômico-político, o MERCOSUL atua como facilitador desse desenvolvimento comercial dos países latino americanos.

  12. Standardizzazione e validazione dei dati della pianificazione urbanistica locale nella regione del Veneto

    Directory of Open Access Journals (Sweden)

    Francesco Tomaello

    2013-06-01

    their GIS datasets using a web service so the data uploaded by Municipalities into the Central GeoDatabase of Region Veneto’s SDI will be ready for automated mosaicking , remodelling (using local data models and INSPIRE Land Use data model and SDI-sharing.

  13. Evaluation of methylation pattern in promoter region of E-cadherin ...

    African Journals Online (AJOL)

    The epithelial cadherin gene (CDH1) has been identified as a tumor suppressor gene located within the 16q22.1 region. The CDH1 gene encodes a transmembrane glycoprotein involved in cell to cell adhesion and loss of CDH1 expression contributes to increased proliferation, invasion and metastasis in breast carcinoma.

  14. Impact of E4 Training and Field Auditing of GSA Heartland Region Facilities

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez, Nicholas; Gowri, Krishnan; Underhill, Ronald M.; Goddard, James K.

    2012-04-01

    To assess the impact of energy efficiency expert evaluation (E4) training and field audits performed since 2007, the Federal Energy Management Program (FEMP) undertook a follow-up study on the implementation of E4 recommendations and an analysis of energy savings. The building property manager and O and M contractor of each facility were interviewed to obtain feedback and implementation status of the E4 recommendations. Overall, there were more than 160 recommendations documented in the E4 reports; about 50% of these recommendations were fully implemented and the remaining 50% either partially implemented or not implemented. In four buildings, the E4 recommendations were aligned with American Recovery and Reinvestment Act of 2009 (ARRA) projects replacing HVAC equipment or upgrading the building control system. The E4 recommendations were not followed-up in two buildings because of uncertainty of the long-term use of the facility or personnel changes. Results of this followon study are reported in this document.

  15. DRIVERS OF E-GOVERNMENT MATURITY IN TWO DEVELOPING REGIONS: FOCUS ON LATIN AMERICA AND SUB-SAHARAN AFRICA

    Directory of Open Access Journals (Sweden)

    Princely Ifinedo

    2012-04-01

    Full Text Available This research focuses on the determinants of e-government (E-gov maturity in two comparable regions of the world i.e. Latin America and Sub-Saharan Africa (LA&SSA. E-gov maturity refers to the growth levels in a country’s online services and its citizens’ online participation in governance. To date, few researchers have focused on the determinants of E-gov maturity in LA&SSA. Given the challenges faced by LA&SSA with regard to the implementations and deployment of technological innovations including E-gov, research such as this current one is needed to enrich insight in such contexts. Building on a prior framework and the modernization theory, the impacts of macro-environmental factors of political, economic, social, and technological dimensions on E-gov maturity in LA&SSA are examined. A 5-year panel data consisting of 160 observations or data points was used for analysis in conjunction with structural equation modeling. The data analysis underscored the pertinence of some of the factors on E-gov maturity in LA&SSA. The implications of the study’s findings for research and policy making are discussed.

  16. Cultivando sociologias públicas nos terrenos nacional, regional e global

    Directory of Open Access Journals (Sweden)

    Michael Burawoy

    2009-10-01

    Full Text Available Neste artigo o autor discute a posição do sociólogo e dos cientistas sociais como "intelectuais", cuja inserção política e institucional é variada, podendo ser profissional, crítica, pública ou voltada para políticas públicas. Em contraposição a um ideal wallersteiniano - de acordo com o qual o intelectual, por um lado, está mais próximo das camadas populares e mais distante do poder e, por outro lado, tem uma responsabilidade ao mesmo tempo analítica, moral e política -, o autor considera que os cientistas sociais podem adotar apenas uma dessas dimensões de cada vez, mas que as trocas entre os gêneros da prática sociológica integram, de maneira positiva, a sua dinâmica profissional. O artigo tem a seguinte estrutura: 1 situa o sociólogo no contexto da sua prática, dando especial atenção ao caráter disciplinar vigente; 2 o qual é ele próprio conformado por diferentes regimes políticos nacionais; 3 para finalmente tratar do âmbito global. A conclusão geral é que os sociólogos não orbitam em um espaço vazio além da economia, mas cumprem suas missões em terrenos ideológico e político, que são locais e nacionais antes de constituírem-se como globais. Reconhecer esses terrenos é a primeira tarefa para qualquer engajamento crítico ou projeto político, pois eles constituem os tijolos de qualquer Sociologia internacional.

  17. Venezuela e ALBA: regionalismo contra-hegemônico e ensino superior para todos Venezuela and the ALBA: counter-hegemonic regionalism and higher education for all

    Directory of Open Access Journals (Sweden)

    Thomas Muhr

    2010-08-01

    Full Text Available Partindo de um quadro teórico neo-gramsciano crítico à globalização, este artigo aplica a nova teoria do regionalismo (NTR e a teoria do regionalismo regulatório (TRR à sua análise e teorização dos tratados de comércio da Aliança Bolivariana para os Povos da Nossa América (ALBA-TCP como regionalismo contra-hegemônico na América Latina e Caribe (ALC. A ALBA está centrada na ideia de um Socialismo do Século XXI, que, como (inicialmente também a Revolução Bolivariana da Venezuela, substitui a 'vantagem competitiva' pela 'vantagem cooperativa'. Em seu caráter de conjunto de processos multidimensionais e transnacionais a ALBA-TCP opera dentro de/transversalmente a um número de setores e escalas, ao mesmo passo que as transformações estruturais são movidas pela interação de agentes do Estado e agentes não estatais. A política de Educação Superior para Todos (ESPT do governo venezuelano rejeita a agenda neoliberal globalizada de mercadorização, privatização e elitismo e reinvindica educação pública gratuita em todos os níveis como um direito humano fundamental. A ESPT está sendo regionalizado em um espaço educacional emergente da ALBA e assume um papel-chave nos processos de democracia direta e participatória, dos quais a construção popular (bottom-up da contra-hegemonia e a redefinição política e econômica da ALC dependem. Antes de produzir sujeitos empreendedores conformes ao capitalismo global, a ESPT procura formar subjetividades ao longo de valores morais de solidariedade e cooperação. Isso será ilustrado com referência a um estudo etnográfico de caso da Universidade Bolivariana da Venezuela (UBV.This paper employs new regionalism theory and regulatory regionalism theory in its analysis and theorisation of the Bolivarian Alliance for the Peoples of Our America (ALBA as a counter-hegemonic Latin American and Caribbean (LAC regionalism. As (initially the regionalisation of Venezuela's Bolivarian

  18. Sequence variation of koala retrovirus transmembrane protein p15E among koalas from different geographic regions

    Science.gov (United States)

    Ishida, Yasuko; McCallister, Chelsea; Nikolaidis, Nikolas; Tsangaras, Kyriakos; Helgen, Kristofer M.; Greenwood, Alex D.; Roca, Alfred L.

    2014-01-01

    The koala retrovirus (KoRV), which is transitioning from an exogenous to an endogenous form, has been associated with high mortality in koalas. For other retroviruses, the envelope protein p15E has been considered a candidate for vaccine development. We therefore examined proviral sequence variation of KoRV p15E in a captive Queensland and three wild southern Australian koalas. We generated 163 sequences with intact open reading frames, which grouped into 39 distinct haplotypes. Sixteen distinct haplotypes comprising 139 of the sequences (85%) coded for the same polypeptide. Among the remaining 23 haplotypes, 22 were detected only once among the sequences, and each had 1 or 2 non-synonymous differences from the majority sequence. Several analyses suggested that p15E was under purifying selection. Important epitopes and domains were highly conserved across the p15E sequences and in previously reported exogenous KoRVs. Overall, these results support the potential use of p15E for KoRV vaccine development. PMID:25462343

  19. Tracking the Global Distribution of Persistent Organic Pollutants Accounting for E-Waste Exports to Developing Regions.

    Science.gov (United States)

    Breivik, Knut; Armitage, James M; Wania, Frank; Sweetman, Andrew J; Jones, Kevin C

    2016-01-19

    Elevated concentrations of various industrial-use Persistent Organic Pollutants (POPs), such as polychlorinated biphenyls (PCBs), have been reported in some developing areas in subtropical and tropical regions known to be destinations of e-waste. We used a recent inventory of the global generation and exports of e-waste to develop various global scale emission scenarios for industrial-use organic contaminants (IUOCs). For representative IUOCs (RIUOCs), only hypothetical emissions via passive volatilization from e-waste were considered whereas for PCBs, historical emissions throughout the chemical life-cycle (i.e., manufacturing, use, disposal) were included. The environmental transport and fate of RIUOCs and PCBs were then simulated using the BETR Global 2.0 model. Export of e-waste is expected to increase and sustain global emissions beyond the baseline scenario, which assumes no export. A comparison between model predictions and observations for PCBs in selected recipient regions generally suggests a better agreement when exports are accounted for. This study may be the first to integrate the global transport of IUOCs in waste with their long-range transport in air and water. The results call for integrated chemical management strategies on a global scale.

  20. Artificial E-region field-aligned plasma irregularities generated at pump frequencies near the second electron gyroharmonic

    Directory of Open Access Journals (Sweden)

    D. L. Hysell

    2009-07-01

    Full Text Available E region ionospheric modification experiments have been performed at HAARP using pump frequencies about 50 kHz above and below the second electron gyroharmonic frequency. Artificial E region field-aligned plasma density irregularities (FAIs were created and observed using the imaging coherent scatter radar near Homer, Alaska. Echoes from FAIs generated with pump frequencies above and below 2Ωe did not appear to differ significantly in experiments conducted on summer afternoons in 2008, and the resonance instability seemed to be at work in either case. We argue that upper hybrid wave trapping and resonance instability at pump frequencies below the second electron gyroharmonic frequency are permitted theoretically when the effects of finite parallel wavenumbers are considered. Echoes from a sporadic E layer were observed to be somewhat weaker when the pump frequency was 50 kHz below the second electron gyroharmonic frequency. This may indicate that finite parallel wavenumbers are inconsistent with wave trapping in thin sporadic E ionization layers.

  1. Artificial E-region field-aligned plasma irregularities generated at pump frequencies near the second electron gyroharmonic

    Directory of Open Access Journals (Sweden)

    D. L. Hysell

    2009-07-01

    Full Text Available E region ionospheric modification experiments have been performed at HAARP using pump frequencies about 50 kHz above and below the second electron gyroharmonic frequency. Artificial E region field-aligned plasma density irregularities (FAIs were created and observed using the imaging coherent scatter radar near Homer, Alaska. Echoes from FAIs generated with pump frequencies above and below 2Ωe did not appear to differ significantly in experiments conducted on summer afternoons in 2008, and the resonance instability seemed to be at work in either case. We argue that upper hybrid wave trapping and resonance instability at pump frequencies below the second electron gyroharmonic frequency are permitted theoretically when the effects of finite parallel wavenumbers are considered. Echoes from a sporadic E layer were observed to be somewhat weaker when the pump frequency was 50 kHz below the second electron gyroharmonic frequency. This may indicate that finite parallel wavenumbers are inconsistent with wave trapping in thin sporadic E ionization layers.

  2. Inter-regional changes in the performance and interpretation of spirometry in Spain: 3E study.

    Science.gov (United States)

    López-Campos, José Luis; Soriano, Joan B; Calle, Myriam

    2014-11-01

    This report shows the results of a nation-wide survey on spirometry to assess regional differences. Observational cross-sectional study conducted by means of a telephone survey in 805 primary care (PC) and specialized centers (SC) in all regions. The survey contacted technicians in charge of spirometry and consisted of 36 questions related to the test. The results showed major differences between regions. Most centers had 1-2 spirometers. The number of spirometry tests per week ranged from 2 to 8.9 in PC and between 34.3 and 98.3 in SC. Some training had been given in most centers (63.6-100% in PC and 60.0-100% in SC) but not on a regular basis. Most centers used several short-acting bronchodilators for the bronchodilation test, but with insufficient inhalations (2.0-3.8 in PC and 2.0-3.3 in SC) and frequently incorrect waiting time (29.4-83.3% PC and 33.3-87.5% in SC). Daily calibration was not performed in all centers (0-100% in PC and 66.7-100% in SC). Significant inter-regional differences in spirometry quality criteria were observed, with 6 or more criteria met in 9.1-84.6% of PC centers and 37.5-100% in SC. Our results show the current situation of spirometry in primary and specialized care in Spain, highlighting considerable variability and areas for improvement. This information should be considered by health officials to improve the quality and accessibility of such tests. Copyright © 2014 SEPAR. Published by Elsevier Espana. All rights reserved.

  3. Public-Privat e Partnership in the System of Regional Healthcare Financing

    Directory of Open Access Journals (Sweden)

    Margarita Yur’evna Molchanova

    2016-05-01

    Full Text Available Healthcare financing reform in the Russian Federation, besides its positive consequences, has led to the emergence of several major organizational and economic problems that hinder the expansion of financing sources for this sphere, which also involves public-private partnership (PPP. The paper highlights the regional specifics of such healthcare projects compared to similar projects of other spheres of the national economy. The author describes the problems of PPP projects implementation in healthcare; they include the insufficiency of substantiation of public-private partnership application in healthcare, and the absence of typical models for establishment of relations between PPP participants. The paper presents the healthcare priorities put forward by the author; these priorities are based on the theory of the life cycle of a service. The author presents her own model for organizing a regional concession, which is the most common form of public-private partnership in healthcare so far. The cluster brings together on a voluntary basis the legally independent organizations that are interested in improving the quality and increasing the accessibility of health services. These can include medical institutions of various forms of ownership located in the region, clinics, facilities, institutions that train healthcare workers, authorities, etc. The author shows that a favorable environment for the formation and implementation of PPP projects can be created under the cluster approach to the organization of healthcare. When establishing the medical cluster, the main task is to organize interaction between all its subjects in the interest of the overall development of healthcare in the region and the implementation of one’s own interests

  4. OECD eXplorer: Making Regional Statistics Come Alive through a Geo-Visual Web-Tool

    Directory of Open Access Journals (Sweden)

    Monica Brezzi

    2011-06-01

    Full Text Available Recent advances in web-enabled graphics technologies have the potential to make a dramatic impact on developing highly interactive Geovisual Analytics applications for the Internet. An emerging and challenging application domain is geovisualization of regional (sub-national statistics. Higher integration drivenby institutional processes and economic globalisation is eroding national borders and creating competition along regional lines in the world market. Sound information at sub-national level and benchmark of regions across borders have gained importance in the policy agenda of many countries. In this paper, we introduce “OECD eXplorer” — an interactive tool for analyzing and communicating gained insights and discoveries about spatial-temporal and multivariate OECD regional data. This database is a potential treasure chest for policy-makers, researchers and citizens to gain a better understanding of a region’s structure and performance and to carry out analysis of territorial trends and disparities based on sound information comparableacross countries. Many approaches and tools have been developed in spatial-related knowledge discovery but generally they do not scale well with dynamic visualization of larger spatial data on the Internet. In this context, we introduce a web-compliant Geovisual Analytics toolkit that supports a broad collection offunctional components for analysis, hypothesis generation and validation. The same tool enables the communicationof results on the basis of a snapshot mechanism that captures, re-uses and shares task-related explorative findings. Further developments underway are in the creation of a generic highly interactive web “eXplorer” platform that can be the foundation for easy customization of similar web applications usingdifferent geographical boundaries and indicators. Given this global dimension, a “generic eXplorer” will be a powerful tool to explore different territorial dimensions

  5. Phase shift analysis of K anti Kπ system in the D and E/IOTA regions

    International Nuclear Information System (INIS)

    Chung, S.U.; Fernow, R.; Kirk, H.

    1985-01-01

    We have performed a high-statistics experiment on the reaction π - p → K + anti K 0 π - n at 8.0 GeV/c. A partial-wave analysis of the K + anti K 0 π - system finds that the D(1285) is mostly a J/sup PG/ = 1 ++ state coupling predominantly to a deltaπ decay channel, while the E(1420) peak consists mostly of a J/sup PG/ = 0 -+ wave with a substantial deltaπ decay mode. There is little evidence of a 1 ++ resonance at the E mass. 10 refs., 3 figs

  6. Louisiana: a model for advancing regional e-Research through cyberinfrastructure.

    Science.gov (United States)

    Katz, Daniel S; Allen, Gabrielle; Cortez, Ricardo; Cruz-Neira, Carolina; Gottumukkala, Raju; Greenwood, Zeno D; Guice, Les; Jha, Shantenu; Kolluru, Ramesh; Kosar, Tevfik; Leger, Lonnie; Liu, Honggao; McMahon, Charlie; Nabrzyski, Jarek; Rodriguez-Milla, Bety; Seidel, Ed; Speyrer, Greg; Stubblefield, Michael; Voss, Brian; Whittenburg, Scott

    2009-06-28

    Louisiana researchers and universities are leading a concentrated, collaborative effort to advance statewide e-Research through a new cyberinfrastructure: computing systems, data storage systems, advanced instruments and data repositories, visualization environments and people, all linked together by software programs and high-performance networks. This effort has led to a set of interlinked projects that have started making a significant difference in the state, and has created an environment that encourages increased collaboration, leading to new e-Research. This paper describes the overall effort, the new projects and environment and the results to date.

  7. Assessing the effects of data selection and representation on the development of reliable E. coli sigma 70 promoter region predictors.

    Directory of Open Access Journals (Sweden)

    Mostafa M Abbas

    Full Text Available As the number of sequenced bacterial genomes increases, the need for rapid and reliable tools for the annotation of functional elements (e.g., transcriptional regulatory elements becomes more desirable. Promoters are the key regulatory elements, which recruit the transcriptional machinery through binding to a variety of regulatory proteins (known as sigma factors. The identification of the promoter regions is very challenging because these regions do not adhere to specific sequence patterns or motifs and are difficult to determine experimentally. Machine learning represents a promising and cost-effective approach for computational identification of prokaryotic promoter regions. However, the quality of the predictors depends on several factors including: i training data; ii data representation; iii classification algorithms; iv evaluation procedures. In this work, we create several variants of E. coli promoter data sets and utilize them to experimentally examine the effect of these factors on the predictive performance of E. coli σ70 promoter models. Our results suggest that under some combinations of the first three criteria, a prediction model might perform very well on cross-validation experiments while its performance on independent test data is drastically very poor. This emphasizes the importance of evaluating promoter region predictors using independent test data, which corrects for the over-optimistic performance that might be estimated using the cross-validation procedure. Our analysis of the tested models shows that good prediction models often perform well despite how the non-promoter data was obtained. On the other hand, poor prediction models seems to be more sensitive to the choice of non-promoter sequences. Interestingly, the best performing sequence-based classifiers outperform the best performing structure-based classifiers on both cross-validation and independent test performance evaluation experiments. Finally, we propose a

  8. Study of midlatitude ionospheric irregularities and E- and F-region coupling based on rocket and radar observations from Japan

    Science.gov (United States)

    Yamamoto, M.

    2015-12-01

    We have been studying ionspheric irregularities in mid-latitude region by using radars, sounding rockets, etc. The mid-latitude ionosphere was considered much stable than those in the equatorial or polar region in the past, but our studies for years have revealed that there are much active variabilities. We found variety of wave-like structures that are specific in the mid-latitudes. One of the phenomena is quasi-periodic echoes (QP echoes) first observed by the MU radar that reflects horizontal plasma-density structures associated to sporadic-E layers. Another phenomenon is medium-scale traveling ionospheric disturbance (MSTID) in the F-region. In the generation mechanism we think that Ionospheric E- and F-region coupling process is important. In this presentation, we will discuss nature of mid-latitude ionosphere based on our observations; the MU radar, sounding rocket campaigns of SEEK-1/2, and recent MSTID rocket experiment from JAXA Uchinoura Space Center in July 2013.

  9. Evaluation of methylation pattern in promoter region of E-cadherin ...

    African Journals Online (AJOL)

    user

    2011-03-07

    Mar 7, 2011 ... promoter methylation in CDH1 gene inactivation in breast cancer, the CpG methylation status of E- ..... 5'CpG island of CDH1 in prostate, lung, liver, bladder, .... and estrogen receptor alpha from Sp1 sites to induce cell cycle.

  10. Binding labour and capital: moral obligation and forms of regulation in a regional economy Ligando o trabalho e o capital: obrigação moral e formas de regulação numa economia regional

    Directory of Open Access Journals (Sweden)

    Susana Narotzky

    2006-11-01

    Full Text Available The article is a critique of models of successful economic development in Europe based on the "economic region" idea. These models stress the usefulness of embedding economic relations in the social fabric ("social capital". The ethnography reveals, however, a conflict-laden space where increased embeddedness produces increased tension within the family and the community. In this "modelic" regional economy in Southern Alicante (Spain, recent violent events have involved local actors in the shoe-wear industry, with resident Chinese entrepreneurs. I will show how this confrontation underlines the rise of local modalities of conflict that build upon the organic and culturally bounded elements of economic production that the model stresses: local homogeneity and common interest. The ethnographic evidence shows the complexity of a "regional economy" in a globalized context where appeals to the State to strengthen and enforce some regulations coexist with appeals to de-regulate other areas of the economy.Este artigo é uma crítica aos modelos de sucesso de desenvolvimento económico na Europa baseados na ideia de "região económica". Estes modelos acentuam a utilidade do encastramento das relações económicas no tecido social ("capital social". No entanto, a etnografia mostra-nos um espaço de conflito onde um crescente encastramento produz um aumento da tensão na família e na comunidade. Nesta economia regional "modelar" do sul de Alicante (Espanha, episódios recentes de violência envolveram actores locais da indústria do calçado com empresários chineses aí residentes. Mostrarei como este confronto ilustra o surgimento de modalidades locais de conflito que se exprimem na base dos elementos orgânicos e de enraizamento cultural da produção económica sublinhados pelo modelo: a homogeneidade local e o interesse comum. A investigação etnográfica mostra a complexidade da "economia regional" num contexto globalizado, onde apelos dirigidos

  11. Variabilidade local e regional da evapotranspiração estimada pelo algoritmo SEBAL Local and regional variability of evapotranspiration estimated by SEBAL algorithm

    Directory of Open Access Journals (Sweden)

    Luis C. J. Moreira

    2010-12-01

    Full Text Available Em face da importância em conhecer a evapotranspiração (ET para uso racional da água na irrigação no contexto atual de escassez desse recurso, algoritmos de estimativa da ET a nível regional foram desenvolvidos utilizando-se de ferramentas de sensoriamento remoto. Este estudo objetivou aplicar o algoritmo SEBAL (Surface Energy Balance Algorithms for Land em três imagens do satélite Landsat 5, do segundo semestre de 2006. As imagens correspondem a áreas irrigadas, floresta nativa densa e a Caatinga do Estado do Ceará (Baixo Acaraú, Chapada do Apodi e Chapada do Araripe. Este algoritmo calcula a evapotranspiração horária a partir do fluxo de calor latente, estimado como resíduo do balanço de energia na superfície. Os valores de ET obtidos nas três regiões foram superiores a 0,60 mm h-1 nas áreas irrigadas ou de vegetação nativa densa. As áreas de vegetação nativa menos densa apresentaram taxa da ET horária de 0,35 a 0,60 mm h-1, e valores quase nulos em áreas degradadas. A análise das médias de evapotranspiração horária pelo teste de Tukey a 5% de probabilidade permitiu evidenciar uma variabilidade significativa local, bem como regional no Estado do Ceará.In the context of water resources scarcity, the rational use of water for irrigation is necessary, implying precise estimations of the actual evapotranspiration (ET. With the recent progresses of remote-sensed technologies, regional algorithms estimating evapotranspiration from satellite observations were developed. This work aimed at applying the SEBAL algorithm (Surface Energy Balance Algorithms for Land at three Landsat-5 images during the second semester of 2006. These images cover irrigated areas, dense native forest areas and caatinga areas in three regions of the state of Ceará (Baixo Acaraú, Chapada do Apodi and Chapada do Araripe. The SEBAL algorithm calculates the hourly evapotranspiration from the latent heat flux, estimated from the surface energy

  12. Acetylcholinesterase (AChE) gene modification in transgenic animals: functional consequences of selected exon and regulatory region deletion.

    Science.gov (United States)

    Camp, Shelley; Zhang, Limin; Marquez, Michael; de la Torre, Brian; Long, Jeffery M; Bucht, Goran; Taylor, Palmer

    2005-12-15

    AChE is an alternatively spliced gene. Exons 2, 3 and 4 are invariantly spliced, and this sequence is responsible for catalytic function. The 3' alternatively spliced exons, 5 and 6, are responsible for AChE disposition in tissue [J. Massoulie, The origin of the molecular diversity and functional anchoring of cholinesterases. Neurosignals 11 (3) (2002) 130-143; Y. Li, S. Camp, P. Taylor, Tissue-specific expression and alternative mRNA processing of the mammalian acetylcholinesterase gene. J. Biol. Chem. 268 (8) (1993) 5790-5797]. The splice to exon 5 produces the GPI anchored form of AChE found in the hematopoietic system, whereas the splice to exon 6 produces a sequence that binds to the structural subunits PRiMA and ColQ, producing AChE expression in brain and muscle. A third alternative RNA species is present that is not spliced at the 3' end; the intron 3' of exon 4 is used as coding sequence and produces the read-through, unanchored form of AChE. In order to further understand the role of alternative splicing in the expression of the AChE gene, we have used homologous recombination in stem cells to produce gene specific deletions in mice. Alternatively and together exon 5 and exon 6 were deleted. A cassette containing the neomycin gene flanked by loxP sites was used to replace the exon(s) of interest. Tissue analysis of mice with exon 5 deleted and the neomycin cassette retained showed very low levels of AChE expression, far less than would have been anticipated. Only the read-through species of the enzyme was produced; clearly the inclusion of the selection cassette disrupted splicing of exon 4 to exon 6. The selection cassette was then deleted in exon 5, exon 6 and exons 5 + 6 deleted mice by breeding to Ella-cre transgenic mice. AChE expression in serum, brain and muscle has been analyzed. Another AChE gene targeted mouse strain involving a region in the first intron, found to be critical for AChE expression in muscle cells [S. Camp, L. Zhang, M. Marquez, B

  13. D- and E-region effects in the auroral zone during a moderately active 24-h period in July 2005

    Directory of Open Access Journals (Sweden)

    J. K. Hargreaves

    2007-08-01

    Full Text Available The effects of energetic electron precipitation into the auroral region at a time of enhanced solar wind have been investigated during a continuous period of 24 h, using the European Incoherent Scatter (EISCAT radar, an imaging riometer, and particle measurements on an orbiting satellite. The relative effects in the E region (120 km and D region (90 km are found to vary during the day, consistent with a gradual hardening of the incoming electron spectrum from pre-midnight to morning. Whereas the night spectra are single peaked, the daytime spectra are found to be double peaked, suggesting the presence of two distinct populations.

    A comparison between the radiowave absorption observed with the riometer and values estimated from the radar data shows generally good agreement, but with some discrepancies suggesting the occurrence of some small-scale features. The height and thickness of the absorbing region are estimated. Two periods of enhanced precipitation and the related radio absorption, one near magnetic midnight and one in the early morning, are studied in detail, including their horizontal structure and movement of the absorption patches.

    A sharp reduction of electron flux recorded on a POES satellite is related to the edge of an absorption region delineated by the imaging riometer. The observed particle flux is compared with a value deduced from the radar data during the overpass, and found to be in general agreement.

  14. D- and E-region effects in the auroral zone during a moderately active 24-h period in July 2005

    Directory of Open Access Journals (Sweden)

    J. K. Hargreaves

    2007-08-01

    Full Text Available The effects of energetic electron precipitation into the auroral region at a time of enhanced solar wind have been investigated during a continuous period of 24 h, using the European Incoherent Scatter (EISCAT radar, an imaging riometer, and particle measurements on an orbiting satellite. The relative effects in the E region (120 km and D region (90 km are found to vary during the day, consistent with a gradual hardening of the incoming electron spectrum from pre-midnight to morning. Whereas the night spectra are single peaked, the daytime spectra are found to be double peaked, suggesting the presence of two distinct populations. A comparison between the radiowave absorption observed with the riometer and values estimated from the radar data shows generally good agreement, but with some discrepancies suggesting the occurrence of some small-scale features. The height and thickness of the absorbing region are estimated. Two periods of enhanced precipitation and the related radio absorption, one near magnetic midnight and one in the early morning, are studied in detail, including their horizontal structure and movement of the absorption patches. A sharp reduction of electron flux recorded on a POES satellite is related to the edge of an absorption region delineated by the imaging riometer. The observed particle flux is compared with a value deduced from the radar data during the overpass, and found to be in general agreement.

  15. The Resistance of E.coli in Child Patients in Bingöl Region

    Directory of Open Access Journals (Sweden)

    İlhan Geçit

    2012-07-01

    Full Text Available Aim: In this study, it has been aimed to put forward the resistance of the antibiotic in urinary infections caused by E.coli. Material and Method: The samples of the urine culture sent from 1412 patients who referred to Bingol State Hospital with the suspicion of urinary tract infection between 2007-2011 were retrospectively analyzed. Those who have recently used the antibiotic were excluded from the study. Results: Of the urine cultures sent from 1412 patients with the suspicion of urinary tract infection, there was reproduction in 113 (8%. E.coli was proliferated in 78 patients (69% detected the reproduction in their urine culture. The gender distribution of the patients proliferated E.coli in their urine culture was respectively 13 male (17% and 65 girls (83%. The age range of the children detected the urinary tract infection acquired from the community was under 7 years 39%. The resistance rates of antibiotic for E.coli were found to be 71% for ampicillin, 53% for amoksilin-clavulanate, 51% for co-trimaksazol, 48% for cephalothin, 37% for cefuroxime, 30% for ciprofloxacin, 25% for cefepime, % 21 for norfloxacin, 21% for gentamicin, 6% for sulbactam-seforazom, 2% for amikacin, and 0% for imipenem and meropenem. Discussion: The resistance rates occurring against the antibiotics are getting more and more important because there has been a longer life expectancy in the age group of the children. For this reason, potential uropathogens and antibiotic sensitivities in children should be considered in the treatment by following closely.

  16. Circular intensity differential scattering (CIDS) measurements in the soft x-ray region of the spectrum (∼16 eV to 500 eV)

    International Nuclear Information System (INIS)

    Maestre, M.F.; Bustamante, C.; Snyder, P.; Rowe, E.; Hansen, R.

    1991-03-01

    We propose the use of recently developed techniques of circular intensity differential scattering (CIDS), as extended to the soft x-ray region of the spectrum (16 eV to 500 eV), to study the higher order organization of the eukaryotic chromosome. CIDS is the difference in scattering power of an object when illuminated by right circularly polarized vs. left circularly polarized electromagnetic radiation of arbitrary wavelength. CIDS has been shown to be a very sensitive measure of the helical organization of the scattering object eg. the eukaryotic chromosome. Preliminary results of measurements of samples of bacteriophages and octopus sperm done at SRC, Wisconsin, show the technique to be very sensitive to the dimensional parameters of the particles interrogated by circularly polarized light. 7 refs., 5 figs

  17. SagE induces highly effective protective immunity against Streptococcus iniae mainly through an immunogenic domain in the extracellular region.

    Science.gov (United States)

    Sun, Yun; Sun, Li; Xing, Ming-qing; Liu, Chun-sheng; Hu, Yong-hua

    2013-11-12

    Streptococcus iniae is a Gram-positive bacterium and a severe pathogen of a wide range of farmed fish. S. iniae possesses a virulence-associated streptolysin S cluster composed of several components, one of which is SagE. SagE a transmembrane protein with one major extracellular region named ECR. This study aimed to develop a SagE-based DNA candidate vaccine against streptococcosis and examine the immunoprotective mechanism of the vaccine. We constructed a DNA vaccine, pSagE, based on the sagE gene and examined its immunological property in a Japanese flounder (Paralichthys olivaceus) model. The results showed that at 7 days post-vaccination, expression of SagE at transcription and translation levels was detected in the tissues of the vaccinated fish. After challenge with S. iniae at one and two months post-vaccination, pSagE-vaccinated fish exhibited relative percent survival (RPS) of 95% and 88% respectively. Immunological analysis showed that (i) pSagE significantly upregulated the expression of a wide range of immune genes, (ii) pSagE induced the production of specific serum antibodies that bound whole-cell S. iniae, and (iii) treatment of S. iniae with pSagE-induced antibodies blocked bacterial invasion of host cells. To localize the immunoprotective domain of SagE, the ECR-expressing DNA vaccine pSagEECR was constructed. Immunization analysis showed that flounder vaccinated with pSagEECR exhibited a RPS of 68%, and that pSagEECR induced serum antibody production and immune gene expression in a manner similar to, though to lower magnitudes than, those induced by pSagE. We in this study developed a DNA vaccine, pSagE, which induces highly protective immunity against S. iniae. The protective effect of pSagE is probably due to its ability to elicit systemic immune response, in particular that of the humoral branch, which leads to production of specific serum antibodies that impair bacterial infection. These results add insights to the immunoprotective mechanism

  18. Spectroscopic research of Lambda hypernuclei up to medium-heavy mass region with the (e,e'K+) reaction

    Energy Technology Data Exchange (ETDEWEB)

    Gogami, Toshiyuki [Tohoku Univ., Sendai (Japan)

    2014-06-01

    In 2009 (August-November), the E05-115 experiment was carried out at JLab to investigate L hypernuclei in the wide mass region up to A = 52 ($7\\atop{Λ}$He, $10\\atop{Λ}$Be, $12\\atop{Λ}$B and $52\\atop{Λ}$V) with the (e,e'K+) reaction. This is the first attempt to investigate a medium heavy L hypernucleus with the (e,e'K+) reaction. Experimentally, it is difficult to measure heavier L hypernuclei as background rates of particles which originate from electromagnetic processes are roughly in proportion to Z2 (Z: target proton number) in the (e,e'K+) experiment. To perform the experiment, many experimental techniques have been developed and introduced such as optimization of the electron spectrometer configuration (tilt method), clean kaon identification, particle tracking under high multiplicity environment, precise energy scale calibration and so on. In the present thesis, experimental results of the elementary process of p(e,e'K+)L, L hypernuclei of $7\\atop{Λ}$He, $10\\atop{Λ}$Be, $12\\atop{Λ}$B and $52\\atop{Λ}$V are shown. Elementary processes of the electroproduction of L and Σ0, p(e,e'K+)L, Σ0 were used for the absolute energy scale calibration of our spectrometer systems. A careful Monte Carlo simulation shows that the binding energy can be obtained with a systematic error of 0.11 MeV with our energy scale calibration method. A study of the elementary process of L is important to understand L hypernuclei as it is essential for theoretical calculations of L hypernuclei. The differential cross section of the p(e,e'K+)L reaction at the small K+ scattering angle (theta-CM/gamma-K approx. 15.5°), the small Q2 (approx 0.01 [GeV/c]2) and the total energy of W = 1.92 GeV, where no experimental data exists was obtained to be 235 ± 13$+28\\atop{-24}$ nb/sr. The ground state (1/2+) binding energy

  19. A INTEGRAÇÃO REGIONAL NA ÁFRICA OCIDENTAL (1960-2015: BALANÇO E PERSPECTIVAS

    Directory of Open Access Journals (Sweden)

    Mamadou Alpha Diallo

    2016-05-01

    Full Text Available O presente artigo procura através de uma análise histórica dos processos de integração regional oeste africana, reafirmar o pioneirismo da região em termos de integração socioeconômica, política e cultural, mas também destacar a persistências das dificuldades e desafios da consolidação da unidade política na região principalmente depois da internalização das fronteiras coloniais. Fixou-se como objetivo entender porque, apesar dos enormes esforços e as diversas tentativas, o sonho pan-africanista de autonomia, união e desenvolvimento está ainda a quem do esperado? Parte-se da hipótese de que, as dificuldades são de natureza histórica (herança colonial e estrutural ligada a difícil relação entre os processos internos de construção do Estado e a inserção do mesmo no Sistema Internacional dominado pelo imperialismo capitalista dos países coloniais e neocoloniais. Ou seja, a baixa velocidade em que andam os processos de integração econômica, politica, sociocultural e principalmente a ausência de autonomia esta estreitamente atrelado aos processos de independência inacabada devido a fatores endógenos e exógenos.

  20. Regionalização e novos rumos para o SUS: a experiência de um colegiado regional Regionalization and new courses to SUS: the experience of a regional college

    Directory of Open Access Journals (Sweden)

    Emerson Assis

    2009-03-01

    Full Text Available Em que pese todos os avanços no Sistema Único de Saúde (SUS desde a sua implantação, são também notórias as suas fragilidades e seus limites. Um deles, não obstante a diretriz constitucional de regionalização, é que até recentemente não havia uma política concreta de estímulo de integração entre os municípios e, consequentemente, de regiões de saúde, tão necessárias à garantia da integralidade da atenção. Nos últimos três anos, entretanto, o Ministério da Saúde, com a implementação do Pacto pela Saúde, na sua dimensão da gestão, iniciou esse processo, que tem se mostrado promissor para o desenvolvimento e crescimento do SUS nacional. Este trabalho apresenta a experiência positiva de implantação de um Colegiado Regional no Estado de São Paulo, na região de Campinas, através da qual gestores e técnicos das secretarias de saúde estão se tornando sujeitos mais "empoderados" da construção da Saúde na região.Despite all the advances that have occurred in Sistema Único de Saúde (SUS - National Health System since its implementation, its weaknesses and limits are also remarkable. One of them, in spite of the constitutional guideline for regionalization, is that, until recently, there had been no concrete policy to stimulate integration between municipalities and, consequently, between health regions, which are necessary to ensure integral care. In the last three years, however, the Ministry of Health, with the implementation of the Health Pact in its management dimension, started this process, which has been promising to the development and growth of the national SUS. This study presents the positive experience of implementation of a Regional College in the State of São Paulo, in the region of Campinas, through which managers and technicians of the health departments are becoming empowered subjects of the construction of Health in the region.

  1. Migração e distribuição regional de renda no Brasil

    OpenAIRE

    Santos, Cézar Augusto Ramos

    2006-01-01

    O objetivo deste trabalho é analisar o impacto da migração interestadual sobre a distribuição de renda regional brasileira. Inicialmente, estima-se uma regressão minnceriana para o logaritmo do salário contra diversas variáveis de controle mais uma dummy de migração, usando dados da Pesquina Nacional de Amostra de Domicílios (PNAD). Em seguida, são construídos contrafactuais em que não há migração entre os estados brasileiros. A partir dessa análise contrafactual, observa-se que a migração pr...

  2. Numerical simulation of mid-latitude ionospheric E-region based on SEEK and SEEK-2 observations

    Directory of Open Access Journals (Sweden)

    T. Yokoyama

    2005-10-01

    Full Text Available Observational campaigns of the mid-latitude ionospheric E-region with sounding rockets and ground-based instruments were conducted in 1996 (SEEK and 2002 (SEEK-2. Both of them were successfully conducted to bring important findings about the mid-latitude E-region and quasi-periodic (QP VHF radar echoes. The observational results in the SEEK and the SEEK-2 are compared with numerical simulations and discussed in this paper. While sporadic-E (Es-layers are actually formed by the observed neutral wind, it is difficult for the constant wind shear to produce the sharp Es-layer gradient. However, once they are formed in the lower E-region, they cannot easily be dissipated by the simple diffusive motion. The polarization electric field, calculated under the condition at the rocket launch time, shows similar amplitude and structure to the measurement around the Es-layer altitude. The structure of the plasma density and the electric field above the Es-layer observed in the SEEK-2 showed a wave-like pattern up to an altitude of 150 km. Considering a mapping of the polarization electric field generated within the Es-layers, gravity waves are the possible source of the wave-like structure of the measured electric fields and sub-peaks of the electron density above the main Es-layers. Fluctuation of the measured magnetic field is reproduced by Hall or field-aligned current driven by the polarization electric field. The current theoretical models for QP echoes and the polarization electric field are basically verified by the discussion in this paper. Keywords. Ionospheric irregularities – Mid-latitude ionosphere – Numerical simulation studies

  3. First measurement of target and double spin asymmetries for polarized e- polarized p --> e p pi0 in the nucleon resonance region above the Delta(1232)

    Energy Technology Data Exchange (ETDEWEB)

    Biselli, Angela; Burkert, Volker; Amaryan, Moscov; Amaryan, Moskov; Asryan, Gegham; Avagyan, Harutyun; Baghdasaryan, Hovhannes; Baillie, Nathan; Ball, J.P.; Ball, Jacques; Baltzell, Nathan; Battaglieri, Marco; Bedlinskiy, Ivan; Bellis, Matthew; Benmouna, Nawal; Berman, Barry; Blaszczyk, Lukasz; Bookwalter, Craig; Boyarinov, Sergey; Bosted, Peter; Bradford, Robert; Branford, Derek; Briscoe, William; Brooks, William; Bultmann, S.; Bueltmann, Stephen; Butuceanu, Cornel; Calarco, John; Careccia, Sharon; Carman, Daniel; Casey, Liam; Chen, Shifeng; Cheng, Lu; Cole, Philip; Collins, Patrick; Coltharp, Philip; Crabb, Donald; Crede, Volker; Dale, Daniel; Dashyan, Natalya; De Masi, Rita; De Vita, Raffaella; De Sanctis, Enzo; Degtiarenko, Pavel; Deur, Alexandre; Dhamija, Seema; Dickson, Richard; Djalali, Chaden; Dodge, Gail; Doughty, David; Dugger, Michael; Dzyubak, Oleksandr; Egiyan, Hovanes; Elfassi, Lamiaa; Elouadrhiri, Latifa; Eugenio, Paul; Fedotov, Gleb; Feuerbach, Robert; Fersch, Robert; Forest, Tony; Fradi, Ahmed; Garcon, Michel; Gavalian, Gagik; Gevorgyan, Nerses; Gilfoyle, Gerard; Giovanetti, Kevin; Girod, Francois-Xavier; Goetz, John; Gohn, Wesley; Gothe, Ralf; Graham, Lewis; Griffioen, Keith; Guidal, Michel; Guler, Nevzat; Guo, Lei; Gyurjyan, Vardan; Hafidi, Kawtar; Hakobyan, Hayk; Hanretty, Charles; Hassall, Neil; Hicks, Kenneth; Hleiqawi, Ishaq; Holtrop, Maurik; Hyde, Charles; Ilieva, Yordanka; Ireland, David; Ishkhanov, Boris; Isupov, Evgeny; Ito, Mark; Jenkins, David; Jo, Hyon-Suk; Johnstone, John; Joo, Kyungseon; Juengst, Henry; Kalantarians, Narbe; Keller, Dustin; Kellie, James; Khandaker, Mahbubul; Kim, Wooyoung; Klein, Andreas; Klein, Franz; Kossov, Mikhail; Krahn, Zebulun; Kubarovsky, Valery; Kuhn, Joachim; Kuhn, Sebastian; Kuleshov, Sergey; Kuznetsov, Viacheslav; Lachniet, Jeff; Laget, Jean; Langheinrich, Jorn; Lawrence, David; Livingston, Kenneth; Lu, Haiyun; MacCormick, Marion; Markov, Nikolai; Mattione, Paul; McKinnon, Bryan; McNabb, John; Mecking, Bernhard; Mestayer, Mac; Meyer, Curtis; Mibe, Tsutomu; Mikhaylov, Konstantin; Mirazita, Marco; Mokeev, Viktor; Moreno, Brahim; Moriya, Kei; Morrow, Steven; Moteabbed, Maryam; Munevar Espitia, Edwin; Mutchler, Gordon; Nadel-Turonski, Pawel; Nasseripour, Rakhsha; Niccolai, Silvia; Niculescu, Gabriel; Niculescu, Maria-Ioana; Niczyporuk, Bogdan; Niroula, Megh; Niyazov, Rustam; Nozar, Mina; Osipenko, Mikhail; Ostrovidov, Alexander; Park, Kil; Park, Seungkyung; Pasyuk, Evgueni; Paterson, Craig; Pereira, Sergio; Pierce, Joshua; Pivnyuk, Nikolay; Pogorelko, Oleg; Pozdnyakov, Sergey; Price, John; Prok, Yelena; Protopopescu, Dan; Raue, Brian; Ricco, Giovanni; Ripani, Marco; Ritchie, Barry; Rosner, Guenther; Rossi, Patrizia; Sabatie, Franck; Saini, Mukesh; Salamanca, Julian; Salgado, Carlos; Santoro, Joseph; Sapunenko, Vladimir; Schott, Diane; Schumacher, Reinhard; Serov, Vladimir; Sharabian, Youri; Sharov, Dmitri; Shvedunov, Nikolay; Smith, Elton; Sober, Daniel; Sokhan, Daria; Stavinskiy, Aleksey; Stepanyan, Samuel; Stepanyan, Stepan; Stokes, Burnham; Stoler, Paul; Strakovski, Igor; Strauch, Steffen; Taiuti, Mauro; Tedeschi, David; Tkabladze, Avtandil; Tkachenko, Svyatoslav; Todor, Luminita; Ungaro, Maurizio; Vineyard, Michael; Vlassov, Alexander; Watts, Daniel; Weinstein, Lawrence; Weygand, Dennis; Williams, M.; Wolin, Elliott; Wood, Michael; Yegneswaran, Amrit; Yurov, Mikhail; Zana, Lorenzo; Zhang, Jixie; Zhao, Bo; Zhao, Zhiwen

    2008-10-01

    DOI: http://dx.doi.org/10.1103/PhysRevC.78.045204
    The exclusive channel polarized proton(polarized e,e prime p)pi0 was studied in the first and second nucleon resonance regions in the Q2 range from 0.187 to 0.770 GeV2 at Jefferson Lab using the CEBAF Large Acceptance Spectrometer (CLAS). Longitudinal target and beam-target asymmetries were extracted over a large range of center-of-mass angles of the pi0 and compared to the unitary isobar model MAID, the dynamic model by Sato and Lee, and the dynamic model DMT. A strong sensitivity to individual models was observed, in particular for the target asymmetry and in the higher invariant mass region. This data set, once included in the global fits of the above models, is expected to place strong constraints on the electrocoupling amplitudes A_{1/2} and S_{1/2} for the Roper resonance N(1400)P11, and the N(1535)S11 and N(1520)D13 states.

  4. Simultaneous VHF radar backscatter and ionosonde observations of low-latitude E region

    Directory of Open Access Journals (Sweden)

    A. K. Patra

    2005-03-01

    Full Text Available The first results of simultaneous observations made on the low-latitude field-aligned irregularities (FAI using the MST radar located at Gadanki (13.5° N, 79.2° E, dip 12.5° and the Es parameters using an ionosonde at a nearby station Sriharikota (13.7° N, 80.1° E, dip 12.6° are presented. The observations show that while the height of the most intense radar echoes is below the virtual height of Es (h'Es during daytime, it is found to be either below or above during nighttime. The strength of the FAI is better correlated with the top penetration frequency (ftEs and the blanketing frequency (fbEs during the night (r=0.4 in both cases as compared to the day (r=0.35 and -0.04, respectively. Furthermore, the signal strength of FAI is reasonably correlated with (ftEs-fbEs during daytime (r=0.59 while very poorly correlated during nighttime (r=0.18. While the radar observations in general appear to have characteristics close to that of mid-latitudes, the relationship of these with the Es parameters are poorer than that of mid-latitudes. The observations reported here, nevertheless, are quite consistent with the expectations based on the gradient drift instability mechanism.

  5. Conserved peptides within the E2 region of Hepatitis C virus induce humoral and cellular responses in goats

    Directory of Open Access Journals (Sweden)

    El Shenawy Reem

    2009-05-01

    Full Text Available Abstract The reason(s why human antibodies raised against hepatitis C virus (HCV E2 epitopes do not offer protection against multiple viral infections may be related to either genetic variations among viral strains particularly within the hypervariable region-1 (HVR-1, low titers of anti E2 antibodies or interference of non neutralizing antibodies with the function of neutralizing antibodies. This study was designed to assess the immunogenic properties of genetically conserved peptides derived from the C-terminal region of HVR-1 as potential therapeutic and/or prophylactic vaccines against HCV infection. Goats immunized with E2-conserved synthetic peptides termed p36 (a.a 430–446, p37(a.a 517–531 and p38 (a.a 412–419 generated high titers of anti-p36, anti-p37 and anti-P38 antibody responses of which only anti- p37 and anti- p38 were neutralizing to HCV particles in sera from patients infected predominantly with genotype 4a. On the other hand anti-p36 exhibited weak viral neutralization capacity on the same samples. Animals super-immunized with single epitopes generated 2 to 4.5 fold higher titers than similar antibodies produced in chronic HCV patients. Also the studied peptides elicited approximately 3 fold increase in cell proliferation of specific antibody-secreting peripheral blood mononuclear cells (PBMC from immunized goats. These results indicate that, besides E1 derived peptide p35 (a.a 315–323 described previously by this laboratory, E2 conserved peptides p37 and p38 represent essential components of a candidate peptide vaccine against HCV infection.

  6. Regional differences in prostaglandin E2 metabolism in human colorectal cancer liver metastases

    International Nuclear Information System (INIS)

    Young, Alastair L; Chalmers, Claire R; Hawcroft, Gillian; Perry, Sarah L; Treanor, Darren; Toogood, Giles J; Jones, Pamela F; Hull, Mark A

    2013-01-01

    Prostaglandin (PG) E 2 plays a critical role in colorectal cancer (CRC) progression, including epithelial-mesenchymal transition (EMT). Activity of the rate-limiting enzyme for PGE 2 catabolism (15-hydroxyprostaglandin dehydrogenase [15-PGDH]) is dependent on availability of NAD+. We tested the hypothesis that there is intra-tumoral variability in PGE 2 content, as well as in levels and activity of 15-PGDH, in human CRC liver metastases (CRCLM). To understand possible underlying mechanisms, we investigated the relationship between hypoxia, 15-PGDH and PGE 2 in human CRC cells in vitro. Tissue from the periphery and centre of 20 human CRCLM was analysed for PGE 2 levels, 15-PGDH and cyclooxygenase (COX)-2 expression, 15-PGDH activity, and NAD+/NADH levels. EMT of LIM1863 human CRC cells was induced by transforming growth factor (TGF) β. PGE 2 levels were significantly higher in the centre of CRCLM compared with peripheral tissue (P = 0.04). There were increased levels of 15-PGDH protein in the centre of CRCLM associated with reduced 15-PGDH activity and low NAD+/NADH levels. There was no significant heterogeneity in COX-2 protein expression. NAD+ availability controlled 15-PGDH activity in human CRC cells in vitro. Hypoxia induced 15-PGDH expression in human CRC cells and promoted EMT, in a similar manner to PGE 2 . Combined 15-PGDH expression and loss of membranous E-cadherin (EMT biomarker) were present in the centre of human CRCLM in vivo. There is significant intra-tumoral heterogeneity in PGE 2 content, 15-PGDH activity and NAD+ availability in human CRCLM. Tumour micro-environment (including hypoxia)-driven differences in PGE 2 metabolism should be targeted for novel treatment of advanced CRC

  7. HENA CLOTHING FROM S K O P J E REGION O F MACEDONIA

    Directory of Open Access Journals (Sweden)

    Melek TUFAN

    2015-08-01

    Full Text Available Anatolian society provided cultural interaction greatly from Asia to Anatolia, from Anatolian to Europa and Africa with the historical improvment and the basic great culture provided by that history. Turkish people sent to Macedonia from interior parts of Anatolia for the r purpose of adopting there, carried their own culture, constructed close relation ship with local people and they enabled to comeinto variety of practice especially with the interaction of Turksh culture and their own culture. After the cultural interaction, Turkish emigrants lernt the Macedonian traditional clothes and the techniques used for sewing and making clothes and they had the first examples of that way of wearing. The differances and specialities taking place in that fashion became the most special heritage of that society. The clothes worn in special events gave information about the people who had them. In the study the purpose was to examine some women clothing samples worn at henanights in Üsküp Region in terms of materials, color, cut, sewing and decorating and help carrying it tonext generations.

  8. GOVERNANÇA METROPOLITANA: DEBATE E EXPERIÊNCIA REGIONAL DA REGIÃO METROPOLITANA DE MARINGÁ

    Directory of Open Access Journals (Sweden)

    Paulo Romano Reschilian

    2011-12-01

    Full Text Available Maringá, município localizado no Norte do Paraná, diferencia-se de outros municípios brasileiros por seu planejamento urbano-regional caracterizar-se em sua organização espacial pelo modelo de cidade-jardim de inspiração inglesa. O artigo pretende abordar como constituíram as regiões metropolitanas brasileiras (instituição federal a estadual, partindo de um breve histórico da instituição da Região Metropolitana de Maringá e análises do processo de constituição dessa configuração regional. Verifica-se assim, que a cidade planejada reflete o “urbanismo à brasileira” e a urbanização desigual da maioria das cidades brasileiras, apresentando a realidade e os desafios quanto à questão metropolitana.

  9. Plasma Vitamin E and Blood Selenium Concentrations in Norwegian Dairy Cows: Regional Differences and Relations to Feeding and Health

    Directory of Open Access Journals (Sweden)

    Østerås O

    2005-12-01

    Full Text Available Plasma α-tocopherol (vit E and blood selenium (Se concentrations in February were determined in samples from 314 dairy cows in Norway, selected to provide a representative subset of the Norwegian dairy cow population. Each sample was followed by a questionnaire with information about feeding of the cow at the time of sampling. The results were correlated to herd data and to calving and health data for each cow from the Norwegian Dairy Herd Recording System and the Norwegian Cattle Health Recording System. The mean concentrations were 6.9 μg vit E per ml plasma and 0.16 μg Se per g blood. Both levels were highest in mid lactation. Plasma vit E varied with the amount of silage fed to the cow, while blood Se varied with the amount of concentrates and mineral supplements, and with geographical region. No differences in vit E or Se levels were found between cows with recorded treatments for mastitis, parturient paresis or reproductive disorders in the lactation during or immediately prior to sampling, and those without such treatments. For ketosis, a small difference in blood Se was found between the groups with or without recorded treatments. It is concluded that winter-fed lactating cows in Norway had an adequate plasma level of vit E and a marginal-to-adequate level of Se.

  10. Plasma Vitamin E and Blood Selenium Concentrations in Norwegian Dairy Cows: Regional Differences and Relations to Feeding and Health

    Directory of Open Access Journals (Sweden)

    Sivertsen T

    2006-12-01

    Full Text Available Plasma α-tocopherol (vit E and blood selenium (Se concentrations in February were determined in samples from 314 dairy cows in Norway, selected to provide a representative subset of the Norwegian dairy cow population. Each sample was followed by a questionnaire with information about feeding of the cow at the time of sampling. The results were correlated to herd data and to calving and health data for each cow from the Norwegian Dairy Herd Recording System and the Norwegian Cattle Health Recording System. The mean concentrations were 6.9 μg vit E per ml plasma and 0.16 μg Se per g blood. Both levels were highest in mid lactation. Plasma vit E varied with the amount of silage fed to the cow, while blood Se varied with the amount of concentrates and mineral supplements, and with geographical region. No differences in vit E or Se levels were found between cows with recorded treatments for mastitis, parturient paresis or reproductive disorders in the lactation during or immediately prior to sampling, and those without such treatments. For ketosis, a small difference in blood Se was found between the groups with or without recorded treatments. It is concluded that winter-fed lactating cows in Norway had an adequate plasma level of vit E and a marginal-to-adequate level of Se.

  11. A floristic study of Kuh-e Khom in Tang Shekan region of Arsanjan county in Fars province

    Directory of Open Access Journals (Sweden)

    Masumeh Zare

    2015-10-01

    Full Text Available A floristic study was done in Kuh-e Khom in east of Arsanjan county as part of the southern Zagros in Fars province. Altitude of the region is ranged from 1740 to 3270 m above sea level. The flora of the region with an emphasis on identifying habitats and the effect of altitude on vegetation were studied and sampling was done from 2010 to 2012. Totally, 440 plant specimens of vascular plant were collected which were belonging to 50 families, 198 genera and 287 species. The angiosperm plants were dominant and from them the dicot plants with 37 families, 167 genera and 246 species had the most diversity. The monocots plants with 9 families, 27 genera and 37 species were the second diversely group in the region. Gymnosperms and Pteridophyte each with two species had the lowest number of species. In respect to species richness, Asteraceae (43 species was the largest family and after that Breassicaceae (33 species, Poaceae (24 species, Fabaceae (24 species, Lamiaceae (22 species, Caryophyllaceae (19 species and Boraginaceae (13 species had the most species diversity. Half of species were therophyte and 68% of species were belonging to Irano-Turanian region.

  12. Monoclonal Antibodies Directed toward the Hepatitis C Virus Glycoprotein E2 Detect Antigenic Differences Modulated by the N-Terminal Hypervariable Region 1 (HVR1), HVR2, and Intergenotypic Variable Region.

    Science.gov (United States)

    Alhammad, Yousef; Gu, Jun; Boo, Irene; Harrison, David; McCaffrey, Kathleen; Vietheer, Patricia T; Edwards, Stirling; Quinn, Charles; Coulibaly, Fásseli; Poumbourios, Pantelis; Drummer, Heidi E

    2015-12-01

    Hepatitis C virus (HCV) envelope glycoproteins E1 and E2 form a heterodimer and mediate receptor interactions and viral fusion. Both E1 and E2 are targets of the neutralizing antibody (NAb) response and are candidates for the production of vaccines that generate humoral immunity. Previous studies demonstrated that N-terminal hypervariable region 1 (HVR1) can modulate the neutralization potential of monoclonal antibodies (MAbs), but no information is available on the influence of HVR2 or the intergenotypic variable region (igVR) on antigenicity. In this study, we examined how the variable regions influence the antigenicity of the receptor binding domain of E2 spanning HCV polyprotein residues 384 to 661 (E2661) using a panel of MAbs raised against E2661 and E2661 lacking HVR1, HVR2, and the igVR (Δ123) and well-characterized MAbs isolated from infected humans. We show for a subset of both neutralizing and nonneutralizing MAbs that all three variable regions decrease the ability of MAbs to bind E2661 and reduce the ability of MAbs to inhibit E2-CD81 interactions. In addition, we describe a new MAb directed toward the region spanning residues 411 to 428 of E2 (MAb24) that demonstrates broad neutralization against all 7 genotypes of HCV. The ability of MAb24 to inhibit E2-CD81 interactions is strongly influenced by the three variable regions. Our data suggest that HVR1, HVR2, and the igVR modulate exposure of epitopes on the core domain of E2 and their ability to prevent E2-CD81 interactions. These studies suggest that the function of HVR2 and the igVR is to modulate antibody recognition of glycoprotein E2 and may contribute to immune evasion. This study reveals conformational and antigenic differences between the Δ123 and intact E2661 glycoproteins and provides new structural and functional data about the three variable regions and their role in occluding neutralizing and nonneutralizing epitopes on the E2 core domain. The variable regions may therefore function to

  13. Entrepreneurial university and regional sustainable development: proposal of a model Universidade empreendedora e o desenvolvimento regional sustentável: proposta de um modelo

    Directory of Open Access Journals (Sweden)

    Frank Leonardo Casado

    2013-03-01

    Full Text Available Universities, are creators of knowledge, are potential actors of sustainable development practices and social responsibility. Even if it is evident the importance of effective actions that are being carried out within the framework of the universities, it is known that society expects much more than they've been doing. Highlights therefore following paradox: on the one hand, the universities, primarily the federal institutions of higher education (IFES, develop many social actions (extension, generate new technologies (search and form quality professionals (teaching. On the other hand, it is possible to say that a larger contribution is required to meet the demands of the population where are inserted, if making urgent greater participation in the process of sustainable development of their regions of comprehensiveness. The quest-to achieve these goals, it was the preparation of foundations for implementation of a program of innovative entrepreneurship. Which shows necessary for allowing the unification of isolated initiatives today, the search for financing of strategic projects, the definition and implementation of policy on entrepreneurship and innovation of institution and the consolidation of administrative structure capable of supporting the demands of teaching, research and extension.DOI: 10.5902/198346597755As universidades, como criadoras e disseminadoras de conhecimento, constituem-se em potenciais agentes de práticas de desenvolvimento sustentável e responsabilidade social. Mesmo que seja evidente a importância das ações efetivas que estão sendo realizadas no âmbito das universidades, sabe-se que a sociedade espera bem mais do que elas já vêm realizando. Evidencia-se, assim, o seguinte paradoxo: por um lado, as universidades, principalmente as Instituições Federais de Ensino (IFES, desenvolvem muitas ações sociais (extensão, geram novas tecnologias (pesquisa e formam profissionais de qualidade (ensino. Por outro lado,

  14. Criminalidad organizada transnacional en Asia-Pacífico: repercusiones para la seguridad regional e internacional

    Directory of Open Access Journals (Sweden)

    Daniel Sansó-Rubert Pascual

    2011-05-01

    Full Text Available Asia-Pacífico es un área de creciente importancia estratégica en clave de seguridad, caracterizada por la multiplicidad de actores con objetivos divergentes y por la naturaleza multiforme de los desafíos presentes. De entre todos ellos destaca una amenaza común e insidiosa: la criminalidad organizada transnacional. Un recorrido geográfico por Asia-Pacífico permite identificar una fecunda variedad de mercados criminales y una riqueza tipológica criminal amplia, hasta el punto de resultar fútil el tratar de establecer una estructura tipo reflejo de la realidad imperante. Las manifestaciones asiáticas del crimen organizado no configuran un fenómeno monolítico; más bien, presentan un panorama poliédrico, complejo y multidimensional, con importantes manifestaciones regionales y creciente proyección internacional. En conjunto, la criminalidad organizada en la región representa uno de los grandes desafíos actuales en términos de proliferación y exportación de crimen organizado. Inercia que se mantiene a comienzos del recientemente inaugurado siglo XXI.

  15. The Effort to Create Customer Engagement on Customer E_Banking (Empirical Studies on Bank BNI Regional Semarang)

    OpenAIRE

    Alimuddin Rizal Rivai; Wahyudi Wahyudi

    2016-01-01

                        This study focused on testing the effect of variable customer value, support systems and knowledge of the customer's products to customer satisfaction and its impact on customer engagement. This study selects the object user's e-banking customers of Bank BNI Regional Semarang. The number of samples in this study of 100 respondents, using purposive sampling technique sampling. Processing data using SPSS version 16.0. Based on a statistical test using linear regression appro...

  16. Quantitative explanation of some electron temperature profiles measured in situ in the high latitude ionospheric E-region

    International Nuclear Information System (INIS)

    Schlegel, K.; Oyama, Koh-ichiro; Hirao, Kunio

    1983-01-01

    E region electron temperature profiles obtained with a rocket experiment in the Antarctica are compared to theoretical electron temperatures calculated from a model. The main heat source in this model is the heating of the electron gas by unstable plasma waves. Very good agreement between both temperatures is obtained between 105 and 115 km altitude, where this heating mechanism is effective. The agreement is also good below this altitude range, after a refinement of the data analysis procedure for the measured temperatures. Several important consequences of the good agreement are pointed out. (author)

  17. The influence of tidal winds in the formation of blanketing sporadic e-layer over equatorial Brazilian region

    Science.gov (United States)

    Resende, Laysa Cristina Araujo; Batista, Inez Staciarini; Denardini, Clezio Marcos; Batista, Paulo Prado; Carrasco, Alexander José; Andrioli, Vânia Fátima; Moro, Juliano

    2018-06-01

    This work analysis the blanketing sporadic layers (Esb) behavior over São Luís, Brazil (2° 31‧ S, 44° 16‧ W, dip: -4.80) which is classified as a transition region between equatorial and low-latitude. Hence, some peculiarities can appear as Esb occurrence instead of the common Esq, which is a non-blanketing irregularity layer. The analysis presented here was obtained using a modified version of a theoretical model for the E region (MIRE), which computes the densities of the metallic ions (Fe+ and Mg+) and the densities of the main molecular ions (NO+, O2+, N2+) by solving the continuity and momentum equations for each one of them. In that model, the Es layer physics driven by both diurnal and semidiurnal tidal winds are taken into account and it was extended in height coverage by adding a novel neutral wind model derived from the all-sky meteor radar measurements. Thus, we provide more trustworthy results related to the Es layer formation in the equatorial region. We verified the contribution of each tidal wind component to the Esb layer formation in this equatorial region. Additionally, we compared the Es layer electron density computed by MIRE with the data obtained by using the blanketing frequency parameter (fbEs) deduced from ionograms. The results show that the diurnal component of the tidal wind is more important in the Esb layer formation whereas the semidiurnal component has a little contribution in our simulations. Finally, it was verified that the modified MIRE presented here can be used to study the Esb layers occurrence over the equatorial region in the Brazilian sector.

  18. AMERICA LATINA: UNA REGION EN RIESGO. POBREZA, INEQUIDAD E INSTITUCIONALIDAD SOCIAL

    Directory of Open Access Journals (Sweden)

    Bernardo Kliksberg

    2011-08-01

    Full Text Available El tema social se halla actualmente en el centro del escenario histórico de América Latina. Se suceden desde las más variadas fuentes los llamados de alerta sobre la magnitud y profundidad de los problemas que sacuden a la región en el campo social. La mayor reunión de Presidentes del Continente, la cumbre hemisférica (Santiago de Chile, 1998 consignó en su declaración final, suscrita por todos los mandatarios, que “superar la pobreza continúa siendo el mayor desafío confrontado por nuestro Hemisferio”. Caracterizando algunos de los principales problemas existentes, los Presidentes indicaron “estamos decididos a remover las barreras que deniegan a los pobres el acceso a nutrición adecuada, servicios sociales, un medio ambiente saludable, créditos y títulos legales sobre su propiedad”. El Secretario General de la CEPAL, José A. Ocampo resaltó (1998 sobre la situación que “siguen aumentando los niveles de pobreza absoluta, los niveles de desigualdad no muestran mejoría y sigue aumentando el empleo en el sector informal”. El Presidente del BID, Enrique V. Iglesias ha destacado (1997 que “el proceso de cambio ha dejado sin resolver en la gran mayoría de los países un tema central: la pobreza crítica y la mala distribución del ingreso”. El Banco Mundial ha hecho continuos señalamientos sobre la gravedad del problema: “América Latina es notable como una región en la que la pobreza, particularmente la pobreza absoluta, no registra mejora alguna” (Burki, 1996, e indicó en reciente conferencia internacional sobre la región (Chile, 1999, los riesgos que corría la democracia en tales condiciones.

  19. The E-domain region of mechano-growth factor inhibits cellular apoptosis and preserves cardiac function during myocardial infarction.

    Science.gov (United States)

    Mavrommatis, Evangelos; Shioura, Krystyna M; Los, Tamara; Goldspink, Paul H

    2013-09-01

    Insulin-like growth factor-1 (IGF-1) isoforms are expressed via alternative splicing. Expression of the minor isoform IGF-1Eb [also known as mechano-growth factor (MGF)] is responsive to cell stress. Since IGF-1 isoforms differ in their E-domain regions, we are interested in determining the biological function of the MGF E-domain. To do so, a synthetic peptide analog was used to gain mechanistic insight into the actions of the E-domain. Treatment of H9c2 cells indicated a rapid cellular uptake mechanism that did not involve IGF-1 receptor activation but resulted in a nuclear localization. Peptide treatment inhibited the intrinsic apoptotic pathway in H9c2 cells subjected to cell stress with sorbitol by preventing the collapse of the mitochondrial membrane potential and inhibition of caspase-3 activation. Therefore, we administered the peptide at the time of myocardial infarction (MI) in mice. At 2 weeks post-MI cardiac function, gene expression and cell death were assayed. A significant decline in both systolic and diastolic function was evident in untreated mice based on PV loop analysis. Delivery of the E-peptide ameliorated the decline in function and resulted in significant preservation of cardiac contractility. Associated with these changes were an inhibition of pathologic hypertrophy and significantly fewer apoptotic nuclei in the viable myocardium of E-peptide-treated mice post-MI. We conclude that administration of the MGF E-domain peptide may provide a means of modulating local tissue IGF-1 autocrine/paracrine actions to preserve cardiac function, prevent cell death, and pathologic remodeling in the heart.

  20. Aspect sensitive E- and F-region SPEAR-enhanced incoherent backscatter observed by the EISCAT Svalbard radar

    Directory of Open Access Journals (Sweden)

    R. S. Dhillon

    2009-01-01

    Full Text Available Previous studies of the aspect sensitivity of heater-enhanced incoherent radar backscatter in the high-latitude ionosphere have demonstrated the directional dependence of incoherent scatter signatures corresponding to artificially excited electrostatic waves, together with consistent field-aligned signatures that may be related to the presence of artificial field-aligned irregularities. These earlier high-latitude results have provided motivation for repeating the investigation in the different geophysical conditions that obtain in the polar cap ionosphere. The Space Plasma Exploration by Active Radar (SPEAR facility is located within the polar cap and has provided observations of RF-enhanced ion and plasma line spectra recorded by the EISCAT Svalbard UHF incoherent scatter radar system (ESR, which is collocated with SPEAR. In this paper, we present observations of aspect sensitive E- and F-region SPEAR-induced ion and plasma line enhancements that indicate excitation of both the purely growing mode and the parametric decay instability, together with sporadic E-layer results that may indicate the presence of cavitons. We note consistent enhancements from field-aligned, vertical and also from 5° south of field-aligned. We attribute the prevalence of vertical scatter to the importance of the Spitze region, and of that from field-aligned to possible wave/irregularity coupling.

  1. Structural region

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. Structural region. The two groups had 4 substitutions similar to Yawat strain. The Yawat strain had 5 unique mutations. 3 in the E2 region and 2 in the E1 region. The mutation, I702V (E2), though different from all the recent Indian and Reunion sequences was similar ...

  2. Experiments with the MD-1 detector at the e+e- collider VEPP-4 in the energy region of Υ mesons

    International Nuclear Information System (INIS)

    Baru, S.E.; Blinov, A.E.; Blinov, V.E.; Bondar, A.E.; Bukin, A.D.; Groshev, V.R.; Eidelman, Yu.I.; Kiselev, V.A.; Klimenko, S.G.; Kolachev, G.M.; Mishnev, S.I.; Onuchin, A.P.; Panin, V.S.; Petrov, V.V.; Protopopov, I.Ya.; Shamov, A.G.; Sidorov, V.A.; Skovpen, Yu.I.; Skrinsky, A.N.; Tayursky, V.A.; Telnov, V.I.; Tikhonov, Yu.A.; Tumaikin, G.M.; Undrus, A.E.; Vorobiov, A.I.; Zhilich, V.N.

    1996-01-01

    This paper reviews physical results obtained at the e + e - collider VEPP-4 with the MD-1 detector. The results of experiments on the Υ meson physics and study of the hadron production in continuum in the energy region 7.2-10.3 GeV as well as the results of study of the two photon reactions are presented. Among results obtained in the upsilon physics: the precise measurement of the Υ(1S), Υ(2S), Υ(3S) masses and the precise determination of the Υ(1S) and Υ(2S) electronic widths. In the experiments on study of the hadron production in continuum the precise measurement of the R was carried out. The peculiarity of the detector is the magnetic field transverse to the orbit plane which provided the possibility to study two photon reactions with tagging one or both scattered electrons even at zero emission angle. Among results on the γγ reactions is the measurement of the two photon total hadronic cross section performed in the double-tag mode. In the QED experiments a new QED effect - the impact parameter cut-off in single bremsstrahlung was discovered. (orig.)

  3. Polarized Structure Function $\\sigma_{LT'}$ for $p({\\vec e},e'K^+)\\Lambda$ in the Nucleon Resonance Region

    Energy Technology Data Exchange (ETDEWEB)

    Nasseripour, Rakhsha; Raue, Brian; Ambrozewicz, Pawel; Carman, Daniel; Amaryan, Moscov; Amaryan, Moskov; Anciant, Eric; Anghinolfi, Marco; Asavapibhop, Burin; Asryan, Gegham; Audit, Gerard; Auger, Thierry; Avagyan, Harutyun; Baghdasaryan, Hovhannes; Baillie, Nathan; Ball, J.P.; Ball, Jacques; Ball, J.P.; Ball, Jacques; Ball, J.P.; Ball, Jacques; Ball, J.P.; Ball, Jacques; Baltzell, Nathan; Barrow, Steve; Battaglieri, Marco; Beard, Kevin; Bedlinskiy, Ivan; Bektasoglu, Mehmet; Bellis, Matthew; Benmouna, Nawal; Berman, Barry; Biselli, Angela; Blaszczyk, Lukasz; Bonner, Billy; Bouchigny, Sylvain; Boyarinov, Sergey; Bradford, Robert; Branford, Derek; Briscoe, William; Brooks, William; Burkert, Volker; Butuceanu, Cornel; Calarco, John; Careccia, Sharon; Casey, Liam; Cetina, Catalina; Chen, Shifeng; Cheng, Lu; Cole, Philip; Collins, Patrick; Coltharp, Philip; Cords, Dieter; Corvisiero, Pietro; Crabb, Donald; Crede, Volker; Dale, Daniel; Dashyan, Natalya; De Masi, Rita; De Vita, Raffaella; De Sanctis, Enzo; Degtiarenko, Pavel; Dennis, Lawrence; Deur, Alexandre; Dhuga, Kalvir; Dickson, Richard; Djalali, Chaden; Dodge, Gail; Doughty, David; Dragovitsch, Peter; Dugger, Michael; Dytman, Steven; Dzyubak, Oleksandr; Egiyan, Hovanes; Egiyan, Kim; Elfassi, Lamiaa; Elouadrhiri, Latifa; Eugenio, Paul; Fatemi, Renee; Fedotov, Gleb; Feldman, Gerald; Feuerbach, Robert; Forest, Tony; Fradi, Ahmed; Funsten, Herbert; Garcon, Michel; Gavalian, Gagik; Gevorgyan, Nerses; Gilfoyle, Gerard; Giovanetti, Kevin; Girard, Pascal; Girod, Francois-Xavier; Goetz, John; Gothe, Ralf; Gothe, Ralf; Griffioen, Keith; Guidal, Michel; Guillo, Matthieu; Guler, Nevzat; Guo, Lei; Gyurjyan, Vardan; Hafidi, Kawtar; Hakobyan, Hayk; Hanretty, Charles; Hardie, John; Heddle, David; Hersman, F.; Hicks, Kenneth; Hleiqawi, Ishaq; Holtrop, Maurik; Hu, Jicun; Hyde, Charles; Ilieva, Yordanka; Ireland, David; Ishkhanov, Boris; Isupov, Evgeny; Ito, Mark; Jenkins, David; Jo, Hyon-Suk; Johnstone, John; Joo, Kyungseon; Juengst, Henry; Kalantarians, Narbe; Kellie, James; Khandaker, Mahbubul; Kim, Kui; Kim, Kyungmo; Kim, Wooyoung; Klein, Andreas; Klein, Franz; Kossov, Mikhail; Krahn, Zebulun; Kramer, Laird; Kubarovsky, Valery; Kuhn, Joachim; Kuhn, Sebastian; Kuleshov, Sergey; Kuznetsov, Viacheslav; Lachniet, Jeff; Laget, Jean; Langheinrich, Jorn; Lawrence, David; Livingston, Kenneth; Lu, Haiyun; Lukashin, Konstantin; MacCormick, Marion; Manak, Joseph; Markov, Nikolai; Mattione, Paul; McAleer, Simeon; McKinnon, Bryan; McNabb, John; Mecking, Bernhard; Mestayer, Mac; Meyer, Curtis; Mibe, Tsutomu; Mikhaylov, Konstantin; Minehart, Ralph; Mirazita, Marco; Miskimen, Rory; Mokeev, Viktor; Moreno, Brahim; Moriya, Kei; Morrow, Steven; Moteabbed, Maryam; Mueller, James; Munevar Espitia, Edwin; Mutchler, Gordon; Nadel-Turonski, Pawel; Niccolai, Silvia; Niculescu, Gabriel; Niculescu, Maria-Ioana; Niczyporuk, Bogdan; Niroula, Megh; Niyazov, Rustam; Nozar, Mina; Osipenko, Mikhail; Ostrovidov, Alexander; Park, Kijun; Pasyuk, Evgueni; Paterson, Craig; Pereira, Sergio; Peterson, Gerald; Philips, Sasha; Pierce, Joshua; Pivnyuk, Nikolay; Pocanic, Dinko; Pogorelko, Oleg; Pozdnyakov, Sergey; Preedom, Barry; Price, John; Procureur, Sebastien; Prok, Yelena; Protopopescu, Dan; Qin, Liming; Riccardi, Gregory; Ricco, Giovanni; Ripani, Marco; Ritchie, Barry; Rosner, Guenther; Rossi, Patrizia; Rubin, Philip; Sabatie, Franck; Salamanca, Julian; Salgado, Carlos; Santoro, Joseph; Sapunenko, Vladimir; Sayre, Donald; Schumacher, Reinhard; Serov, Vladimir; Shafi, Aziz; Sharabian, Youri; Sharov, Dmitri; Shvedunov, Nikolay; Simionatto, Sebastio; Skabelin, Alexander; Smith, Elton; Smith, Lee; Sober, Daniel; Sokhan, Daria; Stavinsky, Aleksey; Stepanyan, Samuel; Stepanyan, Stepan; Stokes, Burnham; Stoler, Paul; Strakovski, Igor; Strauch, Steffen; Taiuti, Mauro; Taylor, Shawn; Tedeschi, David; Thoma, Ulrike; Thompson, Richard; Tkabladze, Avtandil; Tkachenko, Svyatoslav; Ungaro, Maurizio; Vineyard, Michael; Vlassov, Alexander; Wang,

    2008-06-01

    The first measurements of the polarized structure function $\\sigma_{LT'}$ for the reaction $p(\\vec e,e'K^+)\\Lambda$ in the nucleon resonance region are reported. Measurements are included from threshold up to $W$=2.05 GeV for central values of $Q^2$ of 0.65 and 1.00 GeV$^2$, and nearly the entire kaon center-of-mass angular range. $\\sigma_{LT'}$ is the imaginary part of the longitudinal-transverse response and is expected to be sensitive to interferences between competing intermediate s-channel resonances, as well as resonant and non-resonant processes. The results for $\\sigma_{LT'}$ are comparable in magnitude to previously reported results from CLAS for $\\sigma_{LT}$, the real part of the same response. An intriguing sign change in $\\sigma_{LT'}$ is observed in the high $Q^2$ data at $W\\approx 1.9$ GeV. Comparisons to several existing model predictions are shown.

  4. Simulation of the Beam-Beam Effects in e+e- Storage Rings with a Method of Reducing the Region of Mesh

    Energy Technology Data Exchange (ETDEWEB)

    Cai, Yunhai

    2000-08-31

    A highly accurate self-consistent particle code to simulate the beam-beam collision in e{sup +}e{sup -} storage rings has been developed. It adopts a method of solving the Poisson equation with an open boundary. The method consists of two steps: assigning the potential on a finite boundary using the Green's function, and then solving the potential inside the boundary with a fast Poisson solver. Since the solution of the Poisson's equation is unique, the authors solution is exactly the same as the one obtained by simply using the Green's function. The method allows us to select much smaller region of mesh and therefore increase the resolution of the solver. The better resolution makes more accurate the calculation of the dynamics in the core of the beams. The luminosity simulated with this method agrees quantitatively with the measurement for the PEP-II B-factory ring in the linear and nonlinear beam current regimes, demonstrating its predictive capability in detail.

  5. Role Of E-Government In Delivery Of Public Services In Tanzania Electric Supply Company In Ruvuma Region Tanzania

    Directory of Open Access Journals (Sweden)

    Emmanuel Jackson Petro Gunda

    2015-06-01

    Full Text Available ABSTRACT E-government facilitates delivery of public services of relevant government information in electronic form to citizens in a timely manner and better service delivery to citizens. E-government is a kind of governmental administration which is based on Information Communication and Technology Services. Electronic government describes the use of technologies to facilitate the operation of government and disperse of government information and services. The scope of the work was limited to Tanzania Electric Supply Company Limited TANESCO in Ruvuma region. The population of thirty 31 were selected from a total population of 169 public servants use both purposive and stratified random sampling techniques applied. The major findings of study revealed that about 67.7 of response from respondents agree that ICT infrastructures specifically modern computer connected to internet reliable internet speed well organized organization website power availability in public operation contribute to efficient in delivery of services it also noted by respondents to faster decision making speeding up transaction processing and reduce cost. The study greatly recommends that capacity building to public servants on ICT install and strengthening ICT infrastructures to government organizational are inevitable to realise relevant role of e-government in delivery of public services.

  6. A Agenda Social do MERCOSUL: a Relação Estado Nacional e Integração Regional

    Directory of Open Access Journals (Sweden)

    Lúcia Cortes da Costa

    2010-05-01

    Full Text Available

    O artigo analisa o Estado nacional e suas transformações com a criação de espaços supranacionais, sugerindo possíveis desdobramentos do processo de integração regional para formulação e efetivação de políticas sociais. Parte da hipótese de que as transformações desencadeadas pela internacionalização da economia afetam os espaços políticos, redefinindo os Estados nacionais. A construção de mecanismos supranacionais já é identificada na área do comércio, porém no campo das políticas sociais ainda não se têm experiências de instituições supranacionais que operem na garantia dos direitos sociais. O MERCOSUL nasceu com claros objetivos comerciais. No entanto, avançou para uma agenda social que se propõe, ao menos no plano discursivo, à construção de um modelo comum de atuação na área social, com harmonização da legislação trabalhista, previdenciária, propondo a construção de uma cidadania comunitária. O estudo problematiza essa agenda social e conclui apresentando ponderações sobre a possibilidade de se pensar em um padrão de proteção social comum aos cidadãos do bloco regional e a necessidade de mecanismos para a garantia dos direitos sociais.

     

     

    Palavras-chave: Estado; proteção social; cidadania; MERCOSUL.

  7. The Cosmic Ray spectrum in the energy region between 1012 and 1016 eV measured by ARGO–YBJ

    Directory of Open Access Journals (Sweden)

    Montini Paolo

    2017-01-01

    Full Text Available The ARGO-YBJ experiment has been in full and stable data taking at the Yangbajing cosmic ray observatory (Tibet, P.R. China, 4300 m a.s.l. for more than five years. The detector has been designed in order to explore the Cosmic Ray (CR spectrum in an energy range from few TeV up to several PeV. The high segmentation of the detector allows a detailed measurement of the lateral particle distribution which can be exploited on order to identify showers produced by primaries of different mass. The results of the measurement of the all-particle and proton plus helium energy spectra in the energy region between 1012 and 1016 eV are discussed.

  8. Design and characterization for absolute x-ray spectrometry in the 100-10,000 eV region

    International Nuclear Information System (INIS)

    Henke, B.L.

    1986-08-01

    Reviewed here are the design and characterization procedures used in our program for developing absolute x-ray spectrometry in the 100 to 10,000 eV region. Described are the selection and experimental calibration of the x-ray filters, mirror momochromators, crystal/multilayer analyzers, and the photographic (time integrating) and photoelectric (time resolving) position-sensitive detectors. Analytical response functions have been derived that characterize the energy dependence of the mirror and crystal/multilayer reflectivities and of the photographic film and photocathode sensitivities. These response functions permit rapid, small-computer reduction of the experimental spectra to absolute spectra (measured in photons per stearadian from the source for radiative transitions at indicated photon energies). Our x-ray spectrographic systems are being applied to the diagnostics of pulsed, high temperature plasma sources in laser fusion and x-ray laser research. 15 refs., 27 figs

  9. Turbulent fluxes in atmospheric boundary layer of a semi-arid region of N-E Brazil

    International Nuclear Information System (INIS)

    Patel, S. R.; De Fatima Correia, M.; Da Silva, E. M.; Costa, A. M. N.

    2004-01-01

    The preliminary results of the Experiment 'Experimento de Microfisica de Nuvens-EmfiN' (Experiment of microphysics of clouds) conducted by Universidade Estatual de Ceara-UECE at Fortaleza, a semi-arid region of N-E Brazil, are presented. The mean kinematic fluxes of sensible heat and water vapor of the surface boundary layer are estimated by the thermodynamic energy and water vapor conservation equations; and by the Monin-Obukhov similarity theory. The results of the two methods are in good agreement. It is shown that in the absence of sophisticated fast-response turbulence instrumentation and wind data the conservations equations methods are better option for estimation of heat and water vapor fluxes. Further they are useful to study the turbulent fluxes in inhomogeneous condition in time like early morning and late evening boundary layer transitions

  10. E region neutral winds in the postmidnight diffuse aurora during the atmospheric response in aurora 1 rocket campaign

    International Nuclear Information System (INIS)

    Brinkman, D.G.; Walterscheid, R.L.; Lyons, L.R.

    1995-01-01

    Measured E region neutral winds from the Atmospheric Response in Aurora (ARIA 1) rocket campaign are compared with winds predicted by a high-resolution nonhydrostatic dynamical thermosphere model. The ARIA 1 rockets were launched into the postmidnight diffuse aurora during the recovery phase of a substorm. Simulations have shown that electrodynamical coupling between the auroral ionosphere and the thermosphere was expected to be strong during active diffuse auroral conditions. This is the first time that simulations using the time history of detailed specifications of the magnitude and latitudinal variation of the auroral forcing based on measurements have been compared to simultaneous wind measurements. Model inputs included electron densities derived from ground-based airglow measurements, precipitating electron fluxes measured by the rocket, electron densities measured on the rocket, electric fields derived from magnetometer and satellite ion drift measurements, and large-scale background winds from a thermospheric general circulation model. Our model predicted a strong jet of eastward winds at E region heights. A comparison between model predicted and observed winds showed modest agreement. Above 135 km the model predicted zonal winds with the correct sense, the correct profile shape, and the correct altitude of the peak wind. However, it overpredicted the magnitude of the eastward winds by more than a factor or 2. For the meridional winds the model predicted the general sense of the winds but was unable to predict the structure or strength of the winds seen in the observations. Uncertainties in the magnitude and latitudinal structure of the electric field and in the magnitude of the background winds are the most likely sources of error contributing to the differences between model and observed winds. Between 110 and 135 km the agreement between the model and observations was poor because of a large unmodeled jetlike feature in the observed winds

  11. Inclusive particle production in e+e- interactions in the 6 and 7 GeV center-of-mass energy regions

    International Nuclear Information System (INIS)

    Badtke, D.H.

    1978-01-01

    This dissertation describes a portion of the results from experiment SP19 conducted by the Maryland-Pavia-Princeton (MP 2 ) collaboration at the e + e - storage ring SPEAR II at the Stanford Linear Accelerator Center. The inclusive measurements described were obtained in the 6 and 7 GeV center-of-mass energy regions using a small solid angle (ΔΩ/sub MAX/ = 0.085 sr) magnetic spectrometer situated at 90 0 +- 13 0 with respect to the beams. The spectrometer and a conjugate detector opposite the spectrometer were used to measure back-to-back Bhabhas and muons, and the latter were used to normalize results. The inclusive muon signal at = 7.3 GeV with observed multiplicity n/sub CH/ = 2, acoplanarity par. delta/sub A/ > 20 0 and momentum p > 1.15 GeV/c is found to be in excess of QED and expected backgrounds. The background subtracted inclusive cross section is 10.1 +- 5.4 pb/sr. Both the momentum spectrum and the muon branching ratio of b/sub mu/ = 0.17 +- 0.09 are found to be consistent with the tau. An excess of events above expected backgrounds is also observed in those muons with n/sub CH/ > 2 and p > 1.15 GeV/c. The inclusive background subtracted cross section at = 7.3 GeV of 19.0 +- 6.3 pb/sr cannot be explained by the tau and may indicate the weak decays of charmed mesons. 5 references

  12. Chemical and structural analysis of Eucalyptus globulus and E. camaldulensis leaf cuticles: a lipidized cell wall region

    Directory of Open Access Journals (Sweden)

    Paula eGuzmán

    2014-09-01

    Full Text Available The plant cuticle has traditionally been conceived as an independent hydrophobic layer that covers the external epidermal cell wall. Due to its complexity, the existing relationship between cuticle chemical composition and ultra-structure remains unclear to date. This study aimed to examine the link between chemical composition and structure of isolated, adaxial leaf cuticles of Eucalyptus camaldulensis and E. globulus by the gradual extraction and identification of lipid constituents (cutin and soluble lipids, coupled to spectroscopic and microscopic analyses. The soluble compounds and cutin monomers identified could not be assigned to a concrete internal cuticle ultra-structure. After cutin depolymerization, a cellulose network resembling the cell wall was observed, with different structural patterns in the regions ascribed to the cuticle proper and cuticular layer, respectively. Our results suggest that the current cuticle model should be revised, stressing the presence and major role of cell wall polysaccharides. It is concluded that the cuticle may be interpreted as a modified cell wall region which contains additional lipids. The major heterogeneity of the plant cuticle makes it difficult to establish a direct link between cuticle chemistry and structure with the existing methodologies.

  13. Simulation of hadron multiple production by cosmic-ray protons in the incident energy region of 1015 eV

    International Nuclear Information System (INIS)

    Takatsuka, Ichiro

    1984-01-01

    The simulation studies of the unusual cosmic ray families found by the experiment at Mt. Chacaltaya were performed. Those families have a larger number of hadrons than the normal families, or are the families with big transverse extension. The former is called Centauro or Mini-centauro, and the latter is called Binocular and Chiron. In the first simulation, the process was calculated, in which the Lorentz transformation of π-meson multiple production (C-jet) in the energy region of 10 14 eV was made, and the jet with raised energy was combined, and the families were formed. The second simulation was made for the energy region more than 300 TeV, in which the nucleon-antinucleon multiple production with large transverse momentum and the B particle multiple production with larger transverse momentum were assumed. The data used were the C-jet data observed at Mt. Chacaltaya. For the simulation, all the primary particles were considered to be protons. The results of the present simulation study showed that the families with strong hadron components observed at Mt. Chacaltaya might be the new type hadron multiple production such as nucleon-antinucleon multiple production or B-particle multiple production. The total energy of all the families increased with the energy of the primary particles. There are a few families having the same extent of energy and spread as the Chiron. (Kato, T.)

  14. On the height variation of the E-region cowling conductivity – effect of charged dust particles

    Directory of Open Access Journals (Sweden)

    P. Muralikrishna

    2006-11-01

    Full Text Available Height profiles of the Cowling conductivity in the electrojet region, estimated using the atmospheric parameters given by the existing models like CIRA or MSIS and measured electron density profiles, consistently show the heights of the electrojet current intensity peak to be more than 3 km below those estimated from in-situ measurements using magnetometers on board sounding rockets. Kulkarni and Muralikrishna (2005 attempted to explain this to be due to the effect of neutral dust particles. They reported that neutral dust particles, when they exist in sufficient numbers, can modify the collision parameters, especially in the lower E-region, where dust particles of meteoric origin are known to exist in large numbers, and thereby can modify the Cowling conductivity profile in the electrojet region. This work is extended here to include the effect of charged dust particles. Dust particles can become charged negatively by the attachment of ambient free electrons, and can thus reduce the number density of free electrons especially below the electrojet peak. This can alter the vertical profile of the east-west Hall current driven by the vertical Hall polarization field, thereby causing a net reduction in the electrojet current. Such a decrease in the electrojet current may be observed on the ground magnetograms. This mechanism, as proposed here, can operate only during periods of strong meteor shower activity, when the dust particle density at the assumed deposit height of 103 km can reach extreme values (for example, 5×104 cm−3 of 1-µm diameter dust particles. Such a dense dust layer may even cause a reversal in the normally upward vertical Hall polarization field, within the dust layer, causing a reversal of the electrojet currents below the current peak.

  15. Seasonal variation of low-latitude E-region plasma irregularities studied using Gadanki radar and ionosonde

    Directory of Open Access Journals (Sweden)

    D. V. Phanikumar

    2008-07-01

    Full Text Available In this paper, we present seasonal variation of E region field-aligned irregularities (FAIs observed using the Gadanki radar and compare them with the seasonal variation of Es observed from a nearby location SHAR. During daytime, FAIs occur maximum in summer and throughout the day, as compared to other seasons. During nighttime, FAIs occur equally in both summer and winter, and relatively less in equinoxes. Seasonal variations of Es (i.e. ftEs and fbEs show that the daytime activity is maximum in summer and the nighttime activity is maximum in equinoxes. No relation is found between FAIs occurrence/SNR and ftEs/fbEs. FAIs occurrence, however, is found to be related well with (ftEs−fbEs. This aspect is discussed in the light of the present understanding of the mid-latitude Es-FAIs relationship. The seasonal variations of FAIs observed at Gadanki are compared in detail with those of Piura, which show a significant difference in the daytime observations. The observed difference has been discussed considering the factors governing the generation of FAIs.

  16. Aerogammaspectrometric anomalies (K, eU and eTh) from Araras region (SP) and its relations with pedogenetic processes and phosphate fertilizers; Anomalias aerogamaespectrometricas (K, eU e eTh) da quadricula de Araras (SP) e suas relacoes com processos pedogeneticos e fertilizantes fosfatos

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Jocelyn Lopes de; Ferreira, Francisco Jose Fonseca, E-mail: jocelyn_informatica@yahoo.com.br, E-mail: jocelyn.souza@utp.br, E-mail: francisco.ferreira@ufpr.br [Universidade Federal do Parana (LPGA/UFPR), Curitiba, PR (Brazil). Dept. de Geologia. Lab. de Pesquisas em Geofisica Aplicada

    2005-07-15

    Radionuclides are present in the raw materials utilized in the manufacturing of some fertilizers and, consequently, the redistribution of uranium, thorium and potassium by agricultural activities may lead to the contamination of intensively fertilized soils. Airborne gamma-ray data on K, eU and Th have shown the coincidence of aerogammaspectrometric anomalies and diabase sills in the Araras region (SP). This area is situated between the coordinates latitude 22 deg 00'/22 deg 30' South and longitude 47 deg 00' and 47 deg 30' West. As the contents of radionuclides in basic rocks are low and aerial gamma-ray surveys reveal gamma radiation from the 30 cm of the soil profile (coinciding with topsoil), interest has been raised to investigate which soils are included in the anomalies reported, as well as what sort of agricultural activity is carried out, in order to attest whether the source of radioactivity originated from the chemical fertilizers applied, thus establishing the main purpose of the present research. Integration by GIS has revealed that (1) eU and eTh anomalies occur on latossolos roxos massively fertilized with phosphates, on the level and elevated parts of the terrain; (2) high levels of uranium are associated with clay particle size in regoliths developed on diabase sills; (3) potassium and thorium anomalies follow Quaternary alluviums which extend along the banks of the Moji river, the occurrence of anomalous K accounting for the presence of feldspars in the included soils, and the occurrence of eTh related to local fertilization and to the transport of clays and iron oxides from the uppermost parts of the terrain, where the Latossolos Roxos under sugarcane are located. Radiochemical analyses of U and Th in fertilizers were in agreement with the literature, and it has been observed the influence of the geological genesis of the source of the raw material utilized in the production of the fertilizer, as well as the increase in

  17. O FENÔMENO TURISMO: REFLEXÕES SOBRE A COMPLEXIDADE DA CADEIA PRODUTIVA DO TURISMO E DO DESENVOLVIMENTO REGIONAL ENDÓGENO

    Directory of Open Access Journals (Sweden)

    Mary Sandra Guerra Ashton

    2008-01-01

    Full Text Available O artigo apresenta como objetivo principal uma reflexão em torno da problemática relacionada ao desenvolvimento regional endógeno e à cadeia produtiva do turismo. Apóia-se na necessidade de compreender como estas relações podem contribuir para o desempenho de sistemas sociais e econômicos. Para tanto, busca sustentação teórica nas noções de desenvolvimento regional endógeno, desenvolvida por Sen, Veiga e Barquero, e da cadeia produtiva do turismo, a partir de autores como Beni e Leiper, bem como na compreensão do fenômeno turismo conforme De La Torre e Fúster. Pressupõe-se que a atividade turística organizada por meio do enfoque sistêmico e sua implantação em nível municipal ou regional, a partir das potencialidades locais e do conjunto dessas relações, podem resultar em contribuições para o desenvolvimento das regiões. Palavras-chave: Turismo. Fenômeno Social. Cadeia Produtiva do Turismo. Desenvolvimento Regional. Endogenia.

  18. EAS spectrum in the primary energy region above 10 to the 15th power eV by the Akeno and Yakutsk array data

    Science.gov (United States)

    Krasilnikov, D. D.; Knurenko, S. P.; Krasilnikov, A. D.; Pavlov, V. N.; Sleptsov, I. Y.; Yegorova, V. P.

    1985-01-01

    The extensive air showers spectrum on scintillation desity Rko in primary energy region E sub approx. 10 to the 15th power - 10 to the 20th power eV on the Yakutsk array data and recent results of the Akeno is given.

  19. Gyrokinetic Studies of Turbulence in Steep Gradient Region: Role of Turbulence Spreading and E x B Shear

    Energy Technology Data Exchange (ETDEWEB)

    T.S. Hahm; Z. Lin; P.H. Diamond; G. Rewoldt; W.X. Wang; S. Ethier; O. Gurcan; W.W. Lee; W.M. Tang

    2004-12-21

    An integrated program of gyrokinetic particle simulation and theory has been developed to investigate several outstanding issues in both turbulence and neoclassical physics. Gyrokinetic particle simulations of toroidal ion temperature gradient (ITG) turbulence spreading using the GTC code and its related dynamical model have been extended to the case with radially increasing ion temperature gradient, to study the inward spreading of edge turbulence toward the core. Due to turbulence spreading from the edge, the turbulence intensity in the core region is significantly enhanced over the value obtained from simulations of the core region only. Even when the core gradient is within the Dimits shift regime (i.e., self-generated zonal flows reduce the transport to a negligible value), a significant level of turbulence and transport is observed in the core due to spreading from the edge. The scaling of the turbulent front propagation speed is closer to the prediction from our nonlinear diffusion model than one based on linear toroidal coupling. A calculation of ion poloidal rotation in the presence of sharp density and toroidal angular rotation frequency gradients from the GTC-Neo particle simulation code shows that the results are significantly different from the conventional neoclassical theory predictions. An energy conserving set of a fully electromagnetic nonlinear gyrokinetic Vlasov equation and Maxwell's equations, which is applicable to edge turbulence, is being derived via the phase-space action variational Lie perturbation method. Our generalized ordering takes the ion poloidal gyroradius to be on the order of the radial electric field gradient length.

  20. Mutational analysis of the hypervariable region of hepatitis e virus reveals its involvement in the efficiency of viral RNA replication.

    Science.gov (United States)

    Pudupakam, R S; Kenney, Scott P; Córdoba, Laura; Huang, Yao-Wei; Dryman, Barbara A; Leroith, Tanya; Pierson, F William; Meng, Xiang-Jin

    2011-10-01

    The RNA genome of the hepatitis E virus (HEV) contains a hypervariable region (HVR) in ORF1 that tolerates small deletions with respect to infectivity. To further investigate the role of the HVR in HEV replication, we constructed a panel of mutants with overlapping deletions in the N-terminal, central, and C-terminal regions of the HVR by using a genotype 1 human HEV luciferase replicon and analyzed the effects of deletions on viral RNA replication in Huh7 cells. We found that the replication levels of the HVR deletion mutants were markedly reduced in Huh7 cells, suggesting a role of the HVR in viral replication efficiency. To further verify the results, we constructed HVR deletion mutants by using a genetically divergent, nonmammalian avian HEV, and similar effects on viral replication efficiency were observed when the avian HEV mutants were tested in LMH cells. Furthermore, the impact of complete HVR deletion on virus infectivity was tested in chickens, using an avian HEV mutant with a complete HVR deletion. Although the deletion mutant was still replication competent in LMH cells, the complete HVR deletion resulted in a loss of avian HEV infectivity in chickens. Since the HVR exhibits extensive variations in sequence and length among different HEV genotypes, we further examined the interchangeability of HVRs and demonstrated that HVR sequences are functionally exchangeable between HEV genotypes with regard to viral replication and infectivity in vitro, although genotype-specific HVR differences in replication efficiency were observed. The results showed that although the HVR tolerates small deletions with regard to infectivity, it may interact with viral and host factors to modulate the efficiency of HEV replication.

  1. Continuous day-time time series of E-region equatorial electric fields derived from ground magnetic observatory data

    Science.gov (United States)

    Alken, P.; Chulliat, A.; Maus, S.

    2012-12-01

    The day-time eastward equatorial electric field (EEF) in the ionospheric E-region plays an important role in equatorial ionospheric dynamics. It is responsible for driving the equatorial electrojet (EEJ) current system, equatorial vertical ion drifts, and the equatorial ionization anomaly (EIA). Due to its importance, there is much interest in accurately measuring and modeling the EEF. However, there are limited sources of direct EEF measurements with full temporal and spatial coverage of the equatorial ionosphere. In this work, we propose a method of estimating a continuous day-time time series of the EEF at any longitude, provided there is a pair of ground magnetic observatories in the region which can accurately track changes in the strength of the EEJ. First, we derive a climatological unit latitudinal current profile from direct overflights of the CHAMP satellite and use delta H measurements from the ground observatory pair to determine the magnitude of the current. The time series of current profiles is then inverted for the EEF by solving the governing electrodynamic equations. While this method has previously been applied and validated in the Peruvian sector, in this work we demonstrate the method using a pair of magnetometers in Africa (Samogossoni, SAM, 0.18 degrees magnetic latitude and Tamanrasset, TAM, 11.5 degrees magnetic latitude) and validate the resulting EEF values against the CINDI ion velocity meter (IVM) instrument on the C/NOFS satellite. We find a very good 80% correlation with C/NOFS IVM measurements and a root-mean-square difference of 9 m/s in vertical drift velocity. This technique can be extended to any pair of ground observatories which can capture the day-time strength of the EEJ. We plan to apply this work to more observatory pairs around the globe and distribute real-time equatorial electric field values to the community.

  2. Gyrokinetic studies of turbulence in steep gradient region: Role of turbulence spreading and E x B shear

    International Nuclear Information System (INIS)

    Hahm, T.S.; Lin, Z.; Diamond, P.H.; Gurcan, O.; Rewoldt, G.; Wang, W.X.; Ethier, S.; Lee, W.W.; Lewandowski, J.L.V.; Tang, W.M.

    2005-01-01

    An integrated program of gyrokinetic particle simulation and theory has been developed to investigate several outstanding issues in both turbulence and neoclassical physics. Gyrokinetic particle simulations of toroidal ion temperature gradient (ITG) turbulence spreading using the GTC code and its related dynamical model have been extended to the case with radially increasing ion temperature gradient, to study the inward spreading of edge turbulence toward the core. Due to turbulence spreading from the edge, the turbulence intensity in the core region is significantly enhanced over the value obtained from simulations of the core region only. Even when the core gradient is within the Dimits shift regime (i.e., self-generated zonal flows reduce the transport to a negligible value), a significant level of turbulence and transport is observed in the core due to spreading from the edge. The scaling of the turbulent front propagation speed is closer to the prediction from our nonlinear diffusion model than one based on linear toroidal coupling. A calculation of ion poloidal rotation in the presence of sharp density and toroidal angular rotation frequency gradients from the GTC-Neo particle simulation code shows that the results are significantly different from the conventional neoclassical theory predictions. An energy conserving set of a fully electromagnetic nonlinear gyrokinetic Vlasov equation and Maxwell's equations, which is applicable to edge turbulence, is being derived via the phase-space action variational Lie perturbation method. Our generalized ordering takes the ion poloidal gyroradius to be on the order of the radial electric field gradient length. (author)

  3. Virulence profile of different phylogenetic groups of locally isolated community acquired uropathogenic E. coli from Faisalabad region of Pakistan

    Directory of Open Access Journals (Sweden)

    Bashir Saira

    2012-08-01

    Full Text Available Abstract Background Uropathogenic E.coli (UPEC are among major pathogens causing urinary tract infections. Virulence factors are mainly responsible for the severity of these emerging infections. This study was planned to investigate the distribution of virulence genes and cytotoxic effects of UPEC isolates with reference to phylogenetic groups (B2, B1, D and A to understand the presence and impact of virulence factors in the severity of infection in Faisalabad region of Pakistan. Methods In this study phylogenetic analysis, virulence gene identification and cytotoxicity of 59 uropathogenic E.coli isolates obtained from non-hospitalized patients was studied. Results Among 59 isolates, phylogenetic group B2 (50% was most dominant followed by groups A, B1 (19% each and D (12%. Isolates present in group D showed highest presence of virulence genes. The prevalence hlyA (37% was highest followed by sfaDE (27%, papC (24%, cnf1 (20%, eaeA (19% and afaBC3 (14%. Highly hemolytic and highly verotoxic isolates mainly belonged to group D and B2. We also found two isolates with simultaneous presence of three fimbrial adhesin genes present on pap, afa, and sfa operons. This has not been reported before and underlines the dynamic nature of these UPEC isolates. Conclusions It was concluded that in local UPEC isolates from non-hospitalized patients, group B2 was more prevalent. However, group D isolates were most versatile as all were equipped with virulence genes and showed highest level of cytotoxicity.

  4. Shape resonances and the excitation of helium autoionising states by electrons in the 57-66 eV region

    International Nuclear Information System (INIS)

    Burgt, P.J.M. van der; Eck, J. van; Heideman, H.G.M.

    1986-01-01

    Optical excitation functions of singly excited helium states are presented, measured by detecting the yield of emitted photons as a function of the incident electron energy from 56 to 66 eV. Many structures are observed, which are caused by negative-ion resonances and by the decay of autoionising states followed by post-collision interaction. Some of the structures are interpreted as being caused by hitherto unknown shape resonances lying very close to the thresholds of a particular class of autoionising states. As these shape resonances almost exclusively decay to their respective parent (autoionising) states, thereby considerably enhancing the threshold excitation cross sections of these states, they can only be observed via the PCI effect on the excitation functions of (higher lying) singly excited states. Using the recently introduced supermultiplet classification for doubly excited states a selection rule for the near-threshold excitation of doubly excited states by electron impact is deduced from the measurements. Only states with large probabilities in the Wannier region of configuration space (where the two electrons are at nearly equal distances and on opposite sides of the nucleus) are strongly excited. It is pointed out that these states are precisely the states that can support the above mentioned shape resonances at their thresholds. (author)

  5. Microbiological characterization of Serra da Estrela cheese throughout its Appellation d'Origine Protégée region.

    Science.gov (United States)

    Tavaria, F K; Malcata, F X

    1998-05-01

    The purpose of this study was to assess the typical microbiological quality of the most famous Portuguese traditional cheese, Serra da Estrela, and to assess its ripening time and geographical dependence. Ninety-six experimental cheeses manufactured from sixteen batches of milk on eight dairy farms scattered over the Appellation d' Origine Protégée (AOP) region were qualitatively and quantitatively evaluated microbiologically at various ripening times. Viable counts were performed after inoculation on appropriate selective media for aerobic mesophiles and proteolytic and lipolytic microflora, as well as lactococci, lactobacilli, species of Enterobacteriaceae, lactic streptococci, staphylococci, and yeasts. Members of the Enterobacteriaceae and lactic acid bacteria were the predominant microbial groups on all dairy farms throughout maturation; the latter are probably the microbial group responsible for most proteolytic and lipolytic breakdown in Serra da Estrela cheese. The microbial groups whose numbers were most affected by dairy-to-dairy variation were species of Enterobacteriaceae staphylococci, and enterococci, which are the most critical groups in terms of health hazards. It is therefore suggested that tighter control should be implemented at the level of choice of raw materials, in milk-handling practices, and in general throughout the manufacturing process in attempts to standardize production and consistently reduce microbiological risks (even though the distinctiveness of a few final organoleptic characteristics may somehow be reduced.

  6. The Effort to Create Customer Engagement on Customer E_Banking (Empirical Studies on Bank BNI Regional Semarang

    Directory of Open Access Journals (Sweden)

    Alimuddin Rizal Rivai

    2016-12-01

    Full Text Available                     This study focused on testing the effect of variable customer value, support systems and knowledge of the customer's products to customer satisfaction and its impact on customer engagement. This study selects the object user's e-banking customers of Bank BNI Regional Semarang. The number of samples in this study of 100 respondents, using purposive sampling technique sampling. Processing data using SPSS version 16.0. Based on a statistical test using linear regression approach, then of seven hypothesis there are two hypotheses were rejected. The hypothesis is rejected is the influence of customer value on customer engagement, and support systems to customer engagement. While five other hypotheses, namely: the influence of the customer value, support systems, knowledge products to the satisfaction of the customer, as well as the effect of product knowledge and customer satisfaction on customer involvement is proven. Based on the results of this study, it can be concluded that to build customer engagement should be created customer satisfaction. While such satisfaction can be created through providing better customer value, the support system is up to date and easy, and provides knowledge products to customers continuously and thoroughly.

  7. Study of sporadic E layers based on GPS radio occultation measurements and digisonde data over the Brazilian region

    Science.gov (United States)

    Resende, Laysa C. A.; Arras, Christina; Batista, Inez S.; Denardini, Clezio M.; Bertollotto, Thainá O.; Moro, Juliano

    2018-04-01

    This work presents new results about sporadic E-layers (Es layers) using GPS (global positioning system) radio occultation (RO) measurements obtained from the FORMOSAT-3/COSMIC satellites and digisonde data. The RO profiles are used to study the Es layer occurrence as well as its intensity of the signal-to-noise ratio (SNR) of the 50 Hz GPS L1 signal. The methodology was applied to identify the Es layer on RO measurements over Cachoeira Paulista, a low-latitude station in the Brazilian region, in which the Es layer development is not driven tidal winds only as it is at middle latitudes. The coincident events were analyzed using the RO technique and ionosonde observations during the year 2014 to 2016. We used the electron density obtained using the blanketing frequency parameter (fbEs) and the Es layer height (h'Es) acquired from the ionograms to validate the satellite measurements. The comparative results show that the Es layer characteristics extracted from the RO measurements are in good agreement with the Es layer parameters from the digisonde.

  8. Multiple frequency backscatter observations of heater-induced field-aligned striations in the auroral E region

    International Nuclear Information System (INIS)

    Noble, S.T.

    1985-01-01

    In September 1983 a series of HF ionospheric modification experiments were conducted in Scandinavia using the heat facility near Tromosoe Norway. The purpose of these experiments was to examine the mechanisms by which high-power HF radio waves produce geomagnetic field-aligned striations (FAS) in the auroral E region. The vast majority of the backscatter observations were made with radars operating at 47 and 144 MHz (STARE Finland). Additionally, limited observations were conducted at 140 (STARE Norway) and 21 MHz (SAFARI). These radars are sensitive to irregularities having scale lengths between 1 and 7 m across the geomagnetic field lines. During periods of full power O-mode heating, striations having peak cross sections of 40 to 50 dBsm are observed. Striations are not detected during times of X-mode heating. When the heater output is varied, a corresponding change in the cross section is measured. The magnitude of the change is most pronounced for heater level changes in the range 12.5 to 50% of full power. These cross sections are significantly larger than those measured at midlatitudes using the Arecibo heater (approx.10 1 m 2 ). This is consistent with theoretical studies which indicate that it is easier to excite short-scale FAS at places where the geomagnetic dip angle is large. The growth and decay times of the striations are frequency dependent

  9. Highly potent antimicrobial peptides from N-terminal membrane-binding region of E. coli MreB.

    Science.gov (United States)

    Saikia, Karabi; Sravani, Yalavarthi Durga; Ramakrishnan, Vibin; Chaudhary, Nitin

    2017-02-23

    Microbial pathogenesis is a serious health concern. The threat escalates as the existing conventional antimicrobials are losing their efficacy against the evolving pathogens. Peptides hold promise to be developed into next-generation antibiotics. Antimicrobial peptides adopt amphipathic structures that could selectively bind to and disrupt the microbial membranes. Interaction of proteins with membranes is central to all living systems and we reasoned that the membrane-binding domains in microbial proteins could be developed into efficient antimicrobials. This is an interesting approach as self-like sequences could elude the microbial strategies of degrading the antimicrobial peptides, one of the mechanisms of showing resistance to antimicrobials. We selected the 9-residue-long membrane-binding region of E. coli MreB protein. The 9-residue peptide (C-terminal amide) and its N-terminal acetylated analog displayed broad-spectrum activity, killing Gram-negative bacteria, Gram-positive bacteria, and fungi. Extension with a tryptophan residue at the N-terminus drastically improved the activity of the peptides with lethal concentrations ≤10 μM against all the organisms tested. The tryptophan-extended peptides caused complete killing of C. albicans as well as gentamicin and methicillin resistant S. aureus at 5 μM concentration. Lipid-binding studies and electron microscopic analyses of the peptide-treated microbes suggest membrane disruption as the mechanism of killing.

  10. Evaluation of Enhanced High Resolution MODIS/AMSR-E SSTs and the Impact on Regional Weather Forecast

    Science.gov (United States)

    Schiferl, Luke D.; Fuell, Kevin K.; Case, Jonathan L.; Jedlovec, Gary J.

    2010-01-01

    Over the last few years, the NASA Short-term Prediction Research and Transition (SPoRT) Center has been generating a 1-km sea surface temperature (SST) composite derived from retrievals of the Moderate Resolution Imaging Spectroradiometer (MODIS) for use in operational diagnostics and regional model initialization. With the assumption that the day-to-day variation in the SST is nominal, individual MODIS passes aboard the Earth Observing System (EOS) Aqua and Terra satellites are used to create and update four composite SST products each day at 0400, 0700, 1600, and 1900 UTC, valid over the western Atlantic and Caribbean waters. A six month study from February to August 2007 over the marine areas surrounding southern Florida was conducted to compare the use of the MODIS SST composite versus the Real-Time Global SST analysis to initialize the Weather Research and Forecasting (WRF) model. Substantial changes in the forecast heat fluxes were seen at times in the marine boundary layer, but relatively little overall improvement was measured in the sensible weather elements. The limited improvement in the WRF model forecasts could be attributed to the diurnal changes in SST seen in the MODIS SST composites but not accounted for by the model. Furthermore, cloud contamination caused extended periods when individual passes of MODIS were unable to update the SSTs, leading to substantial SST latency and a cool bias during the early summer months. In order to alleviate the latency problems, the SPoRT Center recently enhanced its MODIS SST composite by incorporating information from the Advanced Microwave Scanning Radiometer-EOS (AMSR-E) instruments as well as the Operational Sea Surface Temperature and Sea Ice Analysis. These enhancements substantially decreased the latency due to cloud cover and improved the bias and correlation of the composites at available marine point observations. While these enhancements improved upon the modeled cold bias using the original MODIS SSTs

  11. Distribution of K, eU and Th and evaluation of annual radiation dose in the region of the Serra do Carambei Granite - PR; Distribuicao de K, eU e eTh e avaliacao da dose anual de radiacao na regiao do Granito Serra do Carambei - PR

    Energy Technology Data Exchange (ETDEWEB)

    Godoy, Luiz C., E-mail: luizcgodoy@brturbo.com.br [Departamento de Geociencias, Universidade Estadual de Ponta Grossa, PR (Brazil); Bittencourt, Andre V.L., E-mail: andre@ufpr.br [Laboratorio de Pesquisas Hidrogeologicas - LPH, Departamento de Geologia, Universidade Federal do Parana, Centro Politecnico, Curitiba, PR (Brazil); Santos, Leonardo J.C., E-mail: santos@ufpr.br [Laboratorio de Biogeografia e Solos - LABS, Departamento de Geografia, Universidade Federal do Parana, Centro Politecnico, Curitiba, PR (Brazil); Ferreira, Francisco J.F., E-mail: francisco.ferreira@ufpr.br [Laboratorio de Pesquisas em Geofisica Aplicada - LPGA, Departamento de Geologia, Universidade Federal do Parana, Centro Politecnico, Curitiba, PR (Brazil)

    2011-04-15

    is study was conducted in an area of 14 km in length oriented in the NNE direction by 7.3 km wide, covering the totality of the Serra do Carambei Granite and adjacent units. Located in the northern region of the Alagados dam, Parana State, this granite contains relatively high concentrations of K, eU and eTh, known since the 1970s through airborne and terrestrial gamma-ray spectrometry surveys. Recent radiochemical tests conducted on 61 samples of geological materials such as rocks (17 samples) and material of the weathering mantle and alluvial deposits (44 samples), confirmed the occurrence of radioactive anomalies in this granite, especially in thorium and uranium. The contents of K, eU and eTh obtained in gamma-ray spectrometry survey and radiochemical tests, converted to annual radiation dose (ARD), allowed to evaluate the intensity of natural radiation, whose levels relatively high in certain regions of the study area, can offer hazard to the local populations. The analysis and interpretation of data, as well the preparation of contour maps of K, eU and eTh were fundamental to understand the behavior and mobility of radionuclides in different environmental compartments of the area. (author)

  12. Água e integração regional na África ocidental: Papel dos rios na economia política oeste africana / Water and Regional Integration in West Africa: Role of rivers in the west

    OpenAIRE

    Diallo, Mamadou Alpha; Universidade Federal do Rio Grande do Sul

    2013-01-01

    Este artigo parte da descrição histórica dos diferentes processos sociopolíticos, econômicos e culturais que se desenvolvem no curso do rio Senegal, para avaliar os possíveis conflitos de interesses políticos e econômicos e suas consequências positivas ou negativas para a integração regional dos países da região. Conclui-se que os rios são elementos favoráveis à promoção da cooperação e da integração regional na África Ocidental, apesar de certas tensões existirem entre Estados separados por ...

  13. Development of a Geomagnetic Storm Correction to the International Reference Ionosphere E-Region Electron Densities Using TIMED/SABER Observations

    Science.gov (United States)

    Mertens, C. J.; Xu, X.; Fernandez, J. R.; Bilitza, D.; Russell, J. M., III; Mlynczak, M. G.

    2009-01-01

    Auroral infrared emission observed from the TIMED/SABER broadband 4.3 micron channel is used to develop an empirical geomagnetic storm correction to the International Reference Ionosphere (IRI) E-region electron densities. The observation-based proxy used to develop the storm model is SABER-derived NO+(v) 4.3 micron volume emission rates (VER). A correction factor is defined as the ratio of storm-time NO+(v) 4.3 micron VER to a quiet-time climatological averaged NO+(v) 4.3 micron VER, which is linearly fit to available geomagnetic activity indices. The initial version of the E-region storm model, called STORM-E, is most applicable within the auroral oval region. The STORM-E predictions of E-region electron densities are compared to incoherent scatter radar electron density measurements during the Halloween 2003 storm events. Future STORM-E updates will extend the model outside the auroral oval.

  14. Empirical Storm-Time Correction to the International Reference Ionosphere Model E-Region Electron and Ion Density Parameterizations Using Observations from TIMED/SABER

    Science.gov (United States)

    Mertens, Christoper J.; Winick, Jeremy R.; Russell, James M., III; Mlynczak, Martin G.; Evans, David S.; Bilitza, Dieter; Xu, Xiaojing

    2007-01-01

    The response of the ionospheric E-region to solar-geomagnetic storms can be characterized using observations of infrared 4.3 micrometers emission. In particular, we utilize nighttime TIMED/SABER measurements of broadband 4.3 micrometers limb emission and derive a new data product, the NO+(v) volume emission rate, which is our primary observation-based quantity for developing an empirical storm-time correction the IRI E-region electron density. In this paper we describe our E-region proxy and outline our strategy for developing the empirical storm model. In our initial studies, we analyzed a six day storm period during the Halloween 2003 event. The results of this analysis are promising and suggest that the ap-index is a viable candidate to use as a magnetic driver for our model.

  15. The flow of E-waste material in the Asian region and a reconsideration of international trade policies on E-waste

    International Nuclear Information System (INIS)

    Shinkuma, Takayoshi; Nguyen Thi Minh Huong

    2009-01-01

    End-of-life home appliances discarded in Japan are reused in Southeast Asia; end-of-life computers are reused in China. E-waste scrap generated in Asia is recycled in China, especially in Guangdong Province. The informal sector in that province has been recycling E-waste scrap and its improper recycling methods have caused serious pollution. In response to this problem, there is wide support for a total ban on E-waste trade, including secondhand items and E-waste scrap. Alternatively, we recommend the establishment of an alternative proper recycling system in Asia that needs cooperation among all Asian countries. First, China is urged to promote proper domestic recycling activities by providing a subsidy for proper recycling. Second, Japan, as a main exporter of E-waste, should establish a traceability system that ensures E-waste scrap exported from Japan will be recycled at proper recycling facilities in China

  16. Low-frequency electrostatic waves in the ionospheric E-region: a comparison of rocket observations and numerical simulations

    Directory of Open Access Journals (Sweden)

    L. Dyrud

    2006-11-01

    Full Text Available Low frequency electrostatic waves in the lower parts of the ionosphere are studied by a comparison of observations by instrumented rockets and of results from numerical simulations. Particular attention is given to the spectral properties of the waves. On the basis of a good agreement between the observations and the simulations, it can be argued that the most important nonlinear dynamics can be accounted for in a 2-D numerical model, referring to a plane perpendicular to a locally homogeneous magnetic field. It does not seem necessary to take into account turbulent fluctuations or motions in the neutral gas component. The numerical simulations explain the observed strongly intermittent nature of the fluctuations: secondary instabilities develop on the large scale gradients of the largest amplitude waves, and the small scale dynamics is strongly influenced by these secondary instabilities. We compare potential variations obtained at a single position in the numerical simulations with two point potential-difference signals, where the latter is the adequate representation for the data obtained by instrumented rockets. We can demonstrate a significant reduction in the amount of information concerning the plasma turbulence when the latter signal is used for analysis. In particular we show that the bicoherence estimate is strongly affected. The conclusions have implications for studies of low frequency ionospheric fluctuations in the E and F regions by instrumented rockets, and also for other methods relying on difference measurements, using two probes with large separation. The analysis also resolves a long standing controversy concerning the supersonic phase velocities of these cross-field instabilities being observed in laboratory experiments.

  17. Reaction rate prediction in the supercritical region of H · + OH"- → e"-_a_q + H_2O using μSR

    International Nuclear Information System (INIS)

    Du, T.; Liu, G.; Beninger, J.; Ghandi, K.

    2015-01-01

    Knowledge of reaction rates in the supercritical region for reactions caused by the radiolysis of water is needed to prevent damage to future Supercritical Water-Cooled reactors. In particular, the H · + OH"- → e"-_a_q + H_2O reaction is examined experimentally within the supercritical region by usage of muon spin rotation spectroscopy. Using the obtained data and the 'cage effect' theory, the reaction was modelled and plateau-like behaviour near the critical point was accounted for. (author)

  18. O enoturismo em Portugal : da "cultura" do vinho ao vinho como cultura : a oferta enoturística nacional e as suas implicações no desenvolvimento local e regional

    OpenAIRE

    Vaz, Ana Isabel Inácio Gomes da Silva Lopes, 1974-

    2008-01-01

    Tese de doutoramento, Geografia (Planeamento Regional e Urbano), 2009, Universidade de Lisboa, Faculdade de Letras O Enoturismo é um fenómeno característico de Modernidade, com uma dupla valência e significado: constitui-se como uma actividade turística complementar à oferta turística nacional, predominantemente balnear. Encerra produtos turísticos onde o interesse pelo conhecimento do vinho e da vinha nas suas dimensões material, cultural e gastronómica, ou seja, simbólica, se materializa...

  19. Interfaces da gestão ambiental urbana e gestão regional: análise da relação entre Planos Diretores Municipais e Planos de Bacia Hidrográfica

    OpenAIRE

    Renata Bovo Peres; Ricardo Siloto da Silva

    2013-01-01

    Este artigo relata uma pesquisa que discute como a questão ambiental vem sendo tratada nos instrumentos e práticas de gestão localizadas em dois recortes territoriais: municípios e bacias hidrográficas. Foi analisada a relação da dimensão ambiental com a gestão regional e municipal, por meio dos instrumentos Planos de Bacia Hidrográfica e Planos Diretores Municipais, tendo como locus a Unidade de Gerenciamento de Recursos Hídricos Tietê-Jacaré do Estado de São Paulo. Os objetos de pesquisa se...

  20. O Brasil frente ao conflito regional na América Central: oposição ao intervencionismo e apoio à solução negociada, justa, equilibrada e duradoura (1979-1996

    Directory of Open Access Journals (Sweden)

    Carlos Federico Domínguez Avila

    2003-06-01

    Full Text Available O artigo analisa alguns aspectos da percepção brasileira sobre o conflito regional imperante na América Central, entre 1979 e 1996. Na conclusão sugere-se que essa política fundamentou-se no que aqui se chama de a "tese brasileira" sobre a origem, a evolução e os possíveis mecanismos de resolução para o conflito regional.The article analyzes some aspects of the Brazilian perception about the regional conflict in Central America, between 1979 and 1996. The conclusion suggests that the foreign policy towards the conflict was based on the so-called "Brazilian thesis" about the origin, the evolution and the possible mechanisms of solution to the regional conflict.

  1. Structure of AscE and Induced Burial Regions in AscE and AscG upon Formation of the Chaperone Needle-subunit Complex of Type III Secretion System in Aeromonas Hydrophila

    Energy Technology Data Exchange (ETDEWEB)

    Tan, Y.; Yu, H; Leung, K; Sivaraman, J; Mok, Y

    2008-01-01

    In the type III secretion system (T3SS) of Aeromonas hydrophila, the putative needle complex subunit AscF requires both putative chaperones AscE and AscG for formation of a ternary complex to avoid premature assembly. Here we report the crystal structure of AscE at 2.7 A resolution and the mapping of buried regions of AscE, AscG, and AscF in the AscEG and AscEFG complexes using limited protease digestion. The dimeric AscE is comprised of two helix-turn-helix monomers packed in an antiparallel fashion. The N-terminal 13 residues of AscE are buried only upon binding with AscG, but this region is found to be nonessential for the interaction. AscE functions as a monomer and can be coexpressed with AscG or with both AscG and AscF to form soluble complexes. The AscE binding region of AscG in the AscEG complex is identified to be within the N-terminal 61 residues of AscG. The exposed C-terminal substrate-binding region of AscG in the AscEG complex is induced to be buried only upon binding to AscF. However, the N-terminal 52 residues of AscF remain exposed even in the ternary AscEFG complex. On the other hand, the 35-residue C-terminal region of AscF in the complex is resistant to protease digestion in the AscEFG complex. Site-directed mutagenesis showed that two C-terminal hydrophobic residues, Ile83 and Leu84, of AscF are essential for chaperone binding.

  2. GEOGRAFIA REGIONAL E A INFLUÊNCIA ECONÔMICA DO OURO E DA BORRACHA: dialética escalar na formação do espaço brasileiro

    Directory of Open Access Journals (Sweden)

    Antônia Márcia Duarte Queiroz

    2015-10-01

    Full Text Available O objetivo deste texto é tecer discussões sobre a Geografia Regional no Brasil. A análise está focada no estudo da base econômica do Brasil por meio dos seus períodos econômicos, em especial o do Ouro, efetivamente concretizado na porção centro-sul do país, e o da Borracha, pela extração do látex proveniente da Hevea brasiliensis, a Seringueira, distribuída sobre a vastidão amazônica. A metodologia principal foi realizada por meio de análise bibliográfica, trabalho de campo em Ouro Preto-MG, onde foram realizadas observações e fotografias e articulações em torno da análise comparativa e dialética escalar. O contexto da construção da sociedade brasileira permite inferir conexões paralelas e importantes à construção regional articulada às potencialidades econômicas distribuídas no espaço geográfico. Portanto, a análise empreendida permitiu verificar que as regiões do Brasil possuem uma lógica estruturada a partir do uso e da exploração dos recursos naturais em suas várias fases econômicas, as quais foram relevantes para a organização e formação regional no território.   REGIONAL GEOGRAPHY: ECONOMIC INFLUENCE AND DIALECTIC CLIMB ON THE FORMATION OF THE BRAZILIAN SPACE   Abstract The objective of this text is to weave discussions on the regional geography in Brasil. The analysis is focused on the study of Brasil's economic base through its economic periods, in particular gold, effectively realized in the Center-South of Brasil, and rubber based on the extraction of latex from the rubber tree, Hevea brasiliensis, distributed on the vast Amazon rainforest. The main methodology was performed by means of bibliographical analysis, field work in Ouro Preto-MG, where observations were carried out and photographs and joints around the comparative analysis and dialectic. The context of the construction of the Brazilian society allows inferring parallel connections and important to regional economic potential

  3. DEVELOPMENT OF HERITAGE E.I. KOLBASINA ON INTRODUCTION OF NON\\TRADITIONAL CROPS IN THE CENTRAL REGION OF THE RUSSIAN FEDERATION

    Directory of Open Access Journals (Sweden)

    A. Y. Pavlova

    2014-01-01

    Full Text Available The main direction of half a century of scientific activity of Dr. biol. of Sc. E.I. Kolbasina were the introduction of the Central Region of the Russian the Far Eastern and the study of fruit lianas: Actinidia and Schisandrachinensis.

  4. Beam-helicity associated electroproduction of real photons ep {yields} e{gamma}{pi}N in the {Delta}-resonance region

    Energy Technology Data Exchange (ETDEWEB)

    Airapetian, A. [Giessen Univ. (Germany). 2. Physikalisches Inst.; Michigan Univ., Ann Arbor, MI (United States). Randall Laboratory of Physics; Akopov, N. [Yerevan Physics Institute (Argentina); Aschenauer, E.C. [DESY Zeuthen (Germany)] [and others; Collaboration: HERMES Collaboration

    2013-10-15

    The beam-helicity asymmetry in associated electroproduction of real photons, ep {yields} e{gamma}{pi}N, in the {Delta}(1232)-resonance region is measured using the longitudinally polarized HERA positron beam and an unpolarized hydrogen target. Azimuthal Fourier amplitudes of this asymmetry are extracted separately for two channels, ep {yields} e{gamma}{pi}{sup 0}p and ep {yields} e{gamma}{pi}{sup +}n, from a data set collected with a recoil detector. All asymmetry amplitudes are found to be consistent with zero.

  5. Políticas Públicas de Ciência e Tecnologia no Rio Grande do Sul como um Instrumento de Desenvolvimento Regional

    OpenAIRE

    de Lima, Mário Jaime Gomes; de Oliverira Nascimento, Juliana

    2015-01-01

    As Políticas Públicas de Desenvolvimento Regional, no contexto de Promoção e Valorização das Externalidades da Competitividade Empresarial, proposta por Figueiredo (2009), são organizadas a partir do conceito de impactos externos (externalidades) nos problemas regionais, em especial, no que diz respeito à inovação e tecnologia. Diante disto, o poder estatal, procurando solucionar os impactos dessas externalidades, deve elaborar Políticas Públicas de Ciência e Tecnologia, visando o desenvolvim...

  6. Audiovisivi per línsegnamento e nuove tecnologie nelle classi 2.0 della regione Emilia-Romagna

    Directory of Open Access Journals (Sweden)

    Laura Corazza

    2015-01-01

    Full Text Available I bambini e i ragazzi nel nuovo millennio sono forse più avvezzi alla visione di un film o di una trasmissione televisiva che non alla lettura di un libro. Quello che è certo, è che sono sottoposti a un bombardamento mediatico senza precedenti grazie a canali televisivi specializzati nella produzione di programmi per l’infanzia e l’adolescenza, alla Rete Internet e ai dispositivi mobili di ultima generazione. E a scuola? Come cambia la didattica? Al laboratorio Mela abbiamo documentato con un video l’avvio della prima esperienza delle Cl@ssi 2.0 in Emilia-Romagna nelle scuole secondarie inferiori. Alla fine dei 3 anni di sperimentazione, durante i quali gli insegnanti hanno utilizzato LIM, computer in classe e Moodle per l’insegnamento a distanza, abbiamo invece cercato di capire, con un questionario, come e quanto vengano utilizzati i video per la didattica. Ne sono seguite alcune riflessioni.

  7. Regional power supply in 1998-1999. Progress report of the association of regional utilities - Arbeitsgemeinschaft regionaler Energieversorgungs-Unternehmen - ARE e.V.; Regionale Energieversorgung 1998-1999. Taetigkeitsbericht der Arbeitsgemeinschaft regionaler Energieversorgungs-Unternehmen - ARE - e.V.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-04-01

    The ARE progress report discusses the following issues: Economic development and its effects on power supply; Deregulation of the electricity and gas market; Competition between regional utilities; Energy policy of the new German government; European regulations; Legislation on energy supply; Energy supply and cartel law; Regional supply in the East German states. [German] Der Taetigkeitsbericht der ARE befasst sich mit folgenden Themen: Gesamtwirtschaftliche Entwicklung und ihre Auswirkung auf die Energiewirtschaft, Oeffnung des Monopoles fuer Strom und Gas, Wettbewerb der regionalen Energieversorger, Energiepolitik der neuen Bundesregierung, Europaeische Richtlininen, energiewirtschaftsrecht, Versorgungswirtschaft und Kartellrecht und der Regionalversorgung in den neuen Bundeslaendern.

  8. Limitations of the mean-field description for nuclei in the Pb-region, observed with the (e,e'p) reaction

    International Nuclear Information System (INIS)

    Quint, E.N.M.

    1988-01-01

    The aim of the high-resolution electron induced quasi-elastic proton knockout experiments is to determine absolute occupation numbers for the valence-proton orbits of 208 Pb and to check whether the predicted occupancies of 70 to 80% can be experimentally verified or that the general trend of the much lower spectroscopic factors observed in the lighter nuclei continues. Therefore the spectral function of 208 Pb is mapped out with the (e,e'p) reaction in a missing-momentum range between -50 and 300 MeV/c. The spectroscopic factors for the known discrete hole states in 207 Tl at excitation energies of 0.0 (1/2 + ), 0.35 (3/2 + ), 1.35 (11/2 - ), 1.67 (5/2 + ) and 3.48 MeV (7/2 + ) are determined by comparison with calculated (CDWIA) momentum densities and an l-decomposition is performed for the continuum. Since rather small spectroscopic factors were expected and bearing in mind the large implications for the theory, an additional calibration of the spectroscopic factors deduced from the (e,e'p) data was needed. Such a calibration possibility was found for the 3s 1/2 proton orbit in 208 Pb, which according to the shell-model picture is just filled. Two relative (e,e'p) experiments were performed on the pairs 205 Tl/ 206 Pb and 206 Pb/ 208 Pb which allowed the determination of the absolute 3s 1/2 proton occupation in 205 Tl, 206 Pb and 208 Pb. 47 refs.; 23 tabs

  9. Disputas Comerciais na OMC e no Mercosul: Divergências entre Brasil e Argentina sob a Perspectiva da Integração Regional

    Directory of Open Access Journals (Sweden)

    Caio Peixoto Chain

    2014-01-01

    Full Text Available International trade presents itself as an important form of internationalization of production that influences the growing movement towards regional integration, occurred mainly from the 80s. In the same way that trade relations between countries can boost regional integration, trade disagreements between them can negatively impact this process. This study aimed to analyze trade disputes between Brazil and Argentina triggered through the WTO; these disputes relate to the Dispute Settlement System of Mercosur when driven simultaneously, and verify the impact on Mercosur. Three cases were collected through literature: In the textile sector, agribusiness and petrochemicals. The research concluded that trade disputes between Brazil and Argentina were influenced by private companies that felt in disadvantage towards the bilateral trade agreements. However, for a dispute to be interna - tionally conducted, there is agreement by the national government is there some kind of violation in the international trade law. These situations tend to generate political consequences, usually negative, between the complainant and the respondent country that affect the process of regional integration.

  10. Phylogenetic relationships in Solanaceae and related species based on cpDNA sequence from plastid trnE-trnT region

    Directory of Open Access Journals (Sweden)

    Danila Montewka Melotto-Passarin

    2008-01-01

    Full Text Available Intergenic spacers of chloroplast DNA (cpDNA are very useful in phylogenetic and population genetic studiesof plant species, to study their potential integration in phylogenetic analysis. The non-coding trnE-trnT intergenic spacer ofcpDNA was analyzed to assess the nucleotide sequence polymorphism of 16 Solanaceae species and to estimate its ability tocontribute to the resolution of phylogenetic studies of this group. Multiple alignments of DNA sequences of trnE-trnT intergenicspacer made the identification of nucleotide variability in this region possible and the phylogeny was estimated by maximumparsimony and rooted with Convolvulaceae Ipomoea batatas, the most closely related family. Besides, this intergenic spacerwas tested for the phylogenetic ability to differentiate taxonomic levels. For this purpose, species from four other families wereanalyzed and compared with Solanaceae species. Results confirmed polymorphism in the trnE-trnT region at different taxonomiclevels.

  11. Grau de cobertura dos planos de saúde e distribuição regional do gasto público em saúde Level of private health insurance coverage and regional distribution of public health expenditure

    Directory of Open Access Journals (Sweden)

    Samuel Kilsztajn

    2001-12-01

    Full Text Available O artigo analisa o grau de cobertura dos planos de saúde segundo as classes de rendimento mensal familiar e por unidade da federação e a distribuição dos recursos da Rede-SUS e do gasto público total em saúde por usuário dos serviços públicos de saúde nas regiões Norte-Nordeste e Centro-Sul do país. São apresentados e discutidos também os indicadores do gasto público total em saúde como percentual do PIB gerado nas regiões.This paper analyses the level of private health insurance coverage by classes of income and by states in Brazil and the distribution of the total public health expenditure by public health users in the North-Northeast and Central-South regions of the country. The paper also presents and discusses the total public health expenditure as a percentage of regional GDP.

  12. Struttura produttiva e sviluppo regionale di lungo periodo in Italia (Production Structure and Long-Run Regional Development in Italy

    Directory of Open Access Journals (Sweden)

    Giulio Caianelli

    2012-04-01

    Full Text Available During the 1990s the link between specialisation and/or variety of the production structure and long-run local development has been widely studied both at theoretical and empirical level. Following this research line, the aim of this paper is twofold. First of all, we analyse, by means of transition matrices, the evolution of the model of specialisation/variety of manufacturing industries at regional level in Italy during the twentieth century. Secondly, we investigate, from an econometric point of view, the potential impact of specialisation and/or of variety on the different growth rates of manufacturing employment of the Italian regions during the period 1927-91. In order to carry out this kind of empirical investigation, we have built up a new and original historical data set which, using statistical information drawn from the Italian Industrial Census carried out from 1911 to 1991, provides data on the number of employees for 15 manufacturing industries and for 18 regions.           JEL Codes: R12, L60, R11, R23Keywords: Manufacturing, Regional Development, Regional

  13. Análisis de convergencia económica en el interior de Chiapas: municipios, regiones e inconsistencias aparentes

    Directory of Open Access Journals (Sweden)

    Jorge Alberto LÓPEZ ARÉVALO

    2012-06-01

    Full Text Available A partir de los datos de ingreso per cápita anual estimados por el Programa de las Naciones Unidas para el Desarrollo (PNUD en la elaboración del índice de desarrollo humano municipal en México, se comprueba que, en el interior de Chiapas durante el periodo 2000- 2005, se dio un proceso de fuerte convergencia a nivel municipal al tiempo que no hubo convergencia regional. Para explicar esta aparente inconsistencia, se reexamina el artículo «Regression towards mediocrity in hereditary stature» publicado por Galton en 1886, concluyendo que el nivel de agrupación de los datos (municipal o regional condiciona los resultados del análisis de convergencia, ya que la agrupación de los municipios en regiones origina pérdidas de información que pueden generar fenómenos de «regresión hacia la media» o justo lo contrario, como es el caso. En Chiapas, la convergencia municipal habría dado lugar a la convergencia dentro de las regiones, pero no entre regiones.

  14. A INDICAÇÃO GEOGRÁFICA COMO PROMOTORA DO DESENVOLVIMENTO LOCAL E REGIONAL: O CASO (EM POTENCIAL DO BORDADO DO SERIDÓ

    Directory of Open Access Journals (Sweden)

    Cínthia Kaline Vieira Silva

    2016-03-01

    Full Text Available Esse trabalho busca mostrar como surgiram as indicações geográficas, demonstrando seu potencial como ferramenta para o desenvolvimento regional e local, a partir do empoderamento das populações a partir das liberdades individuais. Com um grande potencial de promoção do desenvolvimento de produtos e processos frutos de um patrimônio cultural e conhecimentos tradicional das localidades, a Indicação Geográfica – IG – é um das formas, previstas na Lei de Propriedade Industrial Brasileira, de proteção dos produtos imateriais e dos princípios do mercado. Estabelecido seu potencial desenvolvimentista, demonstra-se, por meio de um estudo de caso de uma Indicação Geográfica em Potencial, no Seridó do Rio Grande do Norte, como a produção local dos Bordados, possibilita o desenvolvimento sócio econômico local e regional, e de que forma a concessão da IG potencializaria esse processo desenvolvimentista.

  15. The Link between e-Waste and GDP—New Insights from Data from the Pan-European Region

    Directory of Open Access Journals (Sweden)

    Sigrid Kusch

    2017-03-01

    Full Text Available Waste electrical and electronic equipment (WEEE is difficult to sustainably manage. One key issue is the challenge of planning for WEEE flows as current and future quantities of waste are difficult to predict. To address this, WEEE generation and gross domestic product (GDP data from 50 countries of the pan-European region were assessed. A high economic elasticity was identified, indicating that WEEE and GDP are closely interlinked. More detailed analyses revealed that GDP at purchasing power parity (GDP PPP is a more meaningful measure when looking at WEEE flows, as a linear dependency between WEEE generation and GDP PPP was identified. This dependency applies to the whole region, regardless of the economic developmental stage of individual countries. In the pan-European region, an increase of 1000 international $ GDP PPP means an additional 0.5 kg WEEE is generated that requires management.

  16. MOVIMIENTOS SOCIALES E INTEGRACIÓN REGIONAL: EL CASO DE LA ARTICULACIÓN DE MOVIMIENTOS SOCIALES HACIA EL ALBA

    Directory of Open Access Journals (Sweden)

    Karla Díaz Martínez

    2013-12-01

    ALBA (the Bolivarian Alliance for the Peoples of Our Americas is a regional integration entity created as an alternative to the US-proposed FTAA (Free Trade Area of the Americas, ALCA in Spanish. ALBA inaugurates a period that has been referred to as post-neoliberal regionalism. Since its origin, ALBA has been accompanied by social movements with an anti-imperialistic and anti-neoliberal stance. ALBA, itself, generated a social entity: the Social Movements Council. However, in a parallel and autonomous way, the social movements created the Articulation of Social Movements toward ALBA. This article describes the characteristics of this entity for social articulation based on theoretical proposals developed in Latin America, and presents a balance of the potentialities and challenges of social movements in Latin America and their incidence in regional integration.

  17. ANALYSIS OF THE EMPLOYMENT OPPORTUNITIES FOR THE WORKFORCE IN THE SOUTH-WEST OLTENIA REGION IN COMPLEMENTARY ACTIVITIES SUCH AS E-WORK

    Directory of Open Access Journals (Sweden)

    Daniela Enăchescu

    2013-06-01

    Full Text Available South West region covers an area of 29,212 km2, approximately 12.25% of the country (238391 km ² and includes five counties: Dolj, Olt, Valcea, Mehedinti and Gorj. It is bordered by Bulgaria, Serbia and South Muntenia, Central and West. From the total workforce of 828,900 people, 332,300 people are employed in farming, forestry and fishing (40% and only 4500 in the areas of information and communications, respectively in 6600 other activities. The regional unemployment rate was 7.7% in 2011 compared to 7.6% nationally, 7.1% for women respectively 8.3% for men, a level very close to the national average[5][7]. We presented these statistics to highlight the region's potential in the development of e-work activities that would increase employment levels both in urban population and especially in rural areas, low unemployment and thus the local population migration and support sustainable development of the region. This paper aims to analyze the opportunity to develop complementary activities of e-work employment for the South West region.

  18. Inovação, competitividade e desenvolvimento regional: os desafios da reestruturação produtiva do Estado

    OpenAIRE

    Quandt, Carlos Olavo; Universidade Federal do Paraná - UFPR

    2011-01-01

    Este artigo aborda os desafios enfrentados pelo Paraná e por outras regiões que estão em fase de reestruturação de suas bases produtivas no contexto atal de globalizaçãoe liberalização econômica, com a implantação de atividades industriais mais dinâmicias e vinculadas a setores onde predominam padrões tecnológicos e orgaanizacionais de classe mundial.

  19. Functional Requirements on the Design of the Detectors and the Interaction Region of an e+e- Linear Collider with a Push-Pull Arrangement of Detectors

    International Nuclear Information System (INIS)

    Markiewicz, T.

    2009-01-01

    The Interaction Region of the International Linear Collider is based on two experimental detectors working in a push-pull mode. A time efficient implementation of this model sets specific requirements and challenges for many detector and machine systems, in particular the IR magnets, the cryogenics and the alignment system, the beamline shielding, the detector design and the overall integration. This paper attempts to separate the functional requirements of a push pull interaction region and machine detector interface from any particular conceptual or technical solution that might have been proposed to date by either the ILC Beam Delivery Group or any of the three detector concepts. As such, we hope that it provides a set of ground rules for interpreting and evaluating the MDI parts of the proposed detector concept's Letters of Intent, due March 2009. The authors of the present paper are the leaders of the IR Integration Working Group within Global Design Effort Beam Delivery System and the representatives from each detector concept submitting the Letters Of Intent.

  20. Seasonal and Local Time Variations of E-Region Field-Aligned Irregularities Observed with 30.8-MHz Radar at Kototabang, Indonesia

    Directory of Open Access Journals (Sweden)

    Y. Otsuka

    2012-01-01

    Full Text Available A VHF backscatter radar with operating frequency 30.8 MHz has been operated at Kototabang (0.20°S, 100.32°E; dip latitude 10.36°S, Indonesia, since February 2006. We analyzed E-region field-aligned irregularities (FAIs observed by this radar through a year of 2007 and found that the E-region FAI observed at Kototabang can be classified into two groups. One is “descending FAI”. Altitude of the FAI echo region descends with time from 102 km to 88 km altitude during 0700–1000 and 1900–0000 LT in June solstice season. The other is “low-altitude FAI”, which is observed in an altitude range from 88 to 94 km mainly during nighttime. The observed Doppler velocity show distinct local time and altitude dependence. The seasonally averaged zonal velocity above (below approximately 94 km altitude is westward (eastward during daytime and eastward (westward during nighttime. Meridional/vertical velocity perpendicular to the geomagnetic fields is upward during daytime and downward during nighttime. The direction of the FAI velocity above approximately 94 km altitude is consistent with that of the background E × B plasma drifts reported previously.

  1. Nova técnica: operação de Norwood com perfusão regional cerebral e coronariana New technique: Norwood operation with regional cerebral and coronary perfusion

    Directory of Open Access Journals (Sweden)

    Gláucio Furlanetto

    2009-12-01

    Full Text Available OBJETIVO: Avaliar o resultado imediato da operação de Norwood modificado com nova técnica de perfusão regional cerebral (PRCeA anterógrada associado a perfusão regional coronariana (PRCoR retrógrada em substituição à parada circulatória total com hipotermia profunda em crianças portadoras da Síndrome da Hipoplasia do Coração Esquerdo (SHCE com aorta ascendente extremamente hipoplásica (AH. MÉTODOS: No período de dezembro de 2006 a fevereiro de 2008, a operação de Norwood modificado com tubo entre o ventrículo direito e as artérias pulmonares ou shunt tipo Sano foi realizada em oito crianças portadoras de SHCE e aorta ascendente com diâmetro inferior a 3 mm, (quatro do sexo masculino e quatro do sexo feminino com idade média de 9,2 dias (variando de 1 a 29 dias e peso médio de 3,3 kg (variando de 2,7 a 3,8 kg. Utilizada CEC e hipotermia a 25ºC com duas cânulas venosas e anastomose de um enxerto de politetrafluoretileno com a artéria inominada utilizado como linha arterial e para PRCeA. A PRCoR foi realizada por meio de um desvio na linha arterial e colocação de um cateter na aorta ascendente. Foram analisados o resultado cirúrgico imediato e a presença de alterações neurológicas nesse período. RESULTADOS: O resultado cirúrgico imediato revelou mortalidade de 25% e ausência de comprometimento neurológico ao exame clínico. CONCLUSÃO: A operação de Norwood modificado pode ser realizada com PRCeA e PRCoR em crianças com SHCE e AH com resultado cirúrgico imediato satisfatório e ausência de complicações neurológicas.OBJECTIVE: To assess the immediate result of the modified Norwood procedure with new technique of anterograde regional cerebral perfusion (ARCeP and retrograde regional coronary perfusion (RRCoP in substitution of profound hypothermia and circulatory arrest in children with hypoplastic left heart syndrome (HLHS with extremely hypoplastic ascending aorta (HA. METHODS: In the period of

  2. Optical properties of CaWO4 and CaMoO4 crystals in the 4-25 eV region

    International Nuclear Information System (INIS)

    Grasser, R.; Pitt, E.; Scharmann, A.; Zimmerer, G.

    1975-04-01

    The reflection spectra of CaWO 4 and CaMoO 4 single crystals were measured in the region between 4 and 25 eV. The measurements were performed using the electron synchrotron DESY as a light source. Both crystals show very similar spectral features. A relatively sharp, well separated low energy peak is accompanied on the high energy side by two groups of maxima, each group containing three broad main reflection bands which strongly overlap. Besides this, a less pronounced structure is observed over the whole spectral region. The experimental results are discussed in terms of semiempirical MO calculations of the anionic transition metal oxo complexes. (orig.) [de

  3. Reaction rate prediction in the supercritical region of H · + OH{sup -} → e{sup -}{sub aq} + H{sub 2}O using μSR

    Energy Technology Data Exchange (ETDEWEB)

    Du, T., E-mail: tdu@mta.ca [Mount Allison University, Sackville, NB (Canada); Liu, G., E-mail: gliu@mta.ca [Mount Allison University, Sackville, NB (Canada); Beninger, J., E-mail: jgbeninger@mta.ca [Mount Allison University, Sackville, NB (Canada); Ghandi, K., E-mail: kghandi@mta.ca [Mount Allison University, Sackville, NB (Canada)

    2015-07-01

    Knowledge of reaction rates in the supercritical region for reactions caused by the radiolysis of water is needed to prevent damage to future Supercritical Water-Cooled reactors. In particular, the H · + OH{sup -} → e{sup -}{sub aq} + H{sub 2}O reaction is examined experimentally within the supercritical region by usage of muon spin rotation spectroscopy. Using the obtained data and the 'cage effect' theory, the reaction was modelled and plateau-like behaviour near the critical point was accounted for. (author)

  4. Mutational Analysis of the Hypervariable Region of Hepatitis E Virus Reveals Its Involvement in the Efficiency of Viral RNA Replication ▿

    OpenAIRE

    Pudupakam, R. S.; Kenney, Scott P.; Córdoba, Laura; Huang, Yao-Wei; Dryman, Barbara A.; LeRoith, Tanya; Pierson, F. William; Meng, Xiang-Jin

    2011-01-01

    The RNA genome of the hepatitis E virus (HEV) contains a hypervariable region (HVR) in ORF1 that tolerates small deletions with respect to infectivity. To further investigate the role of the HVR in HEV replication, we constructed a panel of mutants with overlapping deletions in the N-terminal, central, and C-terminal regions of the HVR by using a genotype 1 human HEV luciferase replicon and analyzed the effects of deletions on viral RNA replication in Huh7 cells. We found that the replication...

  5. Improvement of the complex mechanism of state administration of E-government process on the regional level

    Directory of Open Access Journals (Sweden)

    K. G. Kondakov

    2017-03-01

    Suggested structure of the Department will contribute to the improvement of administrative relations between national and regional administration levels. According to the offered structure, main tasks of the structural sub-divisions in the above-mentioned Department have also been defined.

  6. EFICIENCIA TECNOLÓGICA Y MERCADO LABORAL. ESTUDIO E IMPLICACIONES EN EL CRECIMIENTO ECONÓMICO REGIONAL

    Directory of Open Access Journals (Sweden)

    José Luis Alfaro Navarro

    2009-06-01

    Full Text Available Actually, in the information society where we are situated, there are many analyses and approaches that emphasize the relationship between the installation of the information and communications technologies with the economic growth of the territories. The technological change and the capacity to educate and to investigate in a country, has conformed basically, in the last times, what is known as intangible capitals or components of the intellectual capital, associated to the productivity and, in addition, with the growth of a country or region through variations in the production function. In this work, it is emphasized in the treatment of this relationship starting from the indicator of regional technological efficiency to determine if this factor bears a better answer before actual scenario of economic deceleration. So, we project and analyze the relationships of this indicator with the regional labour market, fixing the strong impacts taken place in employment destruction in those regions and sectors with lower scores in generator of technological intellectual capital.

  7. Escalas de poder e gestão e a implementação de políticas de desenvolvimento regional no estado do Rio Grande do Sul

    Directory of Open Access Journals (Sweden)

    Antônio Paulo Cargnin

    2014-01-01

    Full Text Available Este artigo tem como objetivo discutir como se comportam e interagem os atores envolvidos na implementação de políticas públicas destinadas à redução das desigualdades regionais nas diferentes escalas de poder e gestão, tomando como caso empírico algumas ações desenvolvidas no estado do Rio Grande do Sul. Para tanto, é destacada a atuação dos principais atores em diferentes políticas, sempre levando em consideração os referenciais teóricos que fundamentam as discussões sobre a questão regional no Brasil e também os documentos produzidos acerca dos pressupostos, resultados e repercussões territoriais dessas políticas. O esforço aqui realizado tem como propósito identificar como as escalas de poder e gestão, consideradas estratégicas para a compreensão das repercussões territoriais das políticas de desenvolvimento regional, influenciam o processo de construção e implementação dessas mesmas políticas.

  8. Oiapoque, aqui começa o Brasil: a fronteira em construção e os desafios do Desenvolvimento Regional

    Directory of Open Access Journals (Sweden)

    Carina Santos de Almeida

    2016-12-01

    Full Text Available O Município de iapoque é a única fronteira brasileira com um território europeu ultramarino, a Guiana Francesa. Particularmente, essa região e sua condição de fronteira se depara com desafios para sua efetiva inserção no processo de desenvolvimento regional, uma vez que apresenta condições distintas das outras fronteiras brasileiras com países autônomos, independentes e envolvidos em acordos transfronteiriços. O Brasil e a Guiana Francesa vivem em descompasso diplomático de restrições que limitam a migração, a cooperação, a solidariedade e as relações comerciais. Nesse sentido, as práticas socioespaciais e econômicas, pautadas nessas dinâmicas de relações restritivas à livre circulação de pessoas e ao comércio, constroem-se muitas vezes à revelia do Estado. Os desafios regionais para o desenvolvimento de Oiapoque abordados neste artigo evidenciam que a invisibilidade social, o isolamento territorial e a condição “marginal” de fronteira são contextos que estão sendo rompidos pelas novas dinâmicas da organização socioeconômica e política emergidas nas últimas décadas.

  9. SU-E-J-272: Auto-Segmentation of Regions with Differentiating CT Numbers for Treatment Response Assessment

    International Nuclear Information System (INIS)

    Yang, C; Noid, G; Dalah, E; Paulson, E; Li, X; Gilat-Schmidt, T

    2015-01-01

    Purpose: It has been reported recently that the change of CT number (CTN) during and after radiation therapy (RT) may be used to assess RT response. The purpose of this work is to develop a tool to automatically segment the regions with differentiating CTN and/or with change of CTN in a series of CTs. Methods: A software tool was developed to identify regions with differentiating CTN using K-mean Cluster of CT numbers and to automatically delineate these regions using convex hull enclosing method. Pre- and Post-RT CT, PET, or MRI images acquired for sample lung and pancreatic cancer cases were used to test the software tool. K-mean cluster of CT numbers within the gross tumor volumes (GTVs) delineated based on PET SUV (standard uptake value of fludeoxyglucose) and/or MRI ADC (apparent diffusion coefficient) map was analyzed. The cluster centers with higher value were considered as active tumor volumes (ATV). The convex hull contours enclosing preset clusters were used to delineate these ATVs with color washed displays. The CTN defined ATVs were compared with the SUV- or ADC-defined ATVs. Results: CTN stability of the CT scanner used to acquire the CTs in this work is less than 1.5 Hounsfield Unit (HU) variation annually. K-mean cluster centers in the GTV have difference of ∼20 HU, much larger than variation due to CTN stability, for the lung cancer cases studied. The dice coefficient between the ATVs delineated based on convex hull enclosure of high CTN centers and the PET defined GTVs based on SUV cutoff value of 2.5 was 90(±5)%. Conclusion: A software tool was developed using K-mean cluster and convex hull contour to automatically segment high CTN regions which may not be identifiable using a simple threshold method. These CTN regions were reasonably overlapped with the PET or MRI defined GTVs

  10. Caratterizzazione di ceppi Listeria monocytogenes isolati da formaggi a pasta molle e semi-molle prelevati nella regione Abruzzo

    Directory of Open Access Journals (Sweden)

    Vicdalia A. Acciari

    2011-01-01

    Full Text Available Sono stati caratterizzati 47 ceppi di Listeria monocytogenes isolati in un’indagine condotta su formaggi prelevati al dettaglio. Cinque formaggi (gorgonzola, taleggio, asiago, crescenza e brie sono stati selezionati tra quelli a pasta semi molle e molle di maggior consumo su scala nazionale e più frequentemente contaminati da Listeria monocytogenes. Per ogni ceppo è stato determinato il sierotipo, il pattern di resistenza agli antibiotici e il profilo di macrorestrizione con la Pulsed Field Gel Electrophoresis (PFGE. I principali sierotipi rilevati sono risultati l’1/2a (76,6% e l’1/2c (21,3% mentre il sierotipo 1/2b è stato rilevato solo in 1 campione. Il 97,9% dei ceppi è risultato resistente all’oxicillina, l’80,9% alla lincomicina e il 78,7% alla clindamicina. La resistenza a 2 antibiotici è stata rilevata nel 17% dei ceppi con due diversi pattern (OXCC, OXL mentre a 3 nel 70,2% con un unico profilo (OXCCL. Non sono stati rilevati ceppi sensibili a tutte le molecole testate. Con l’analisi combinata dei profili di macrorestrizione di AscI e ApaI, sono stati identificati 11 pulsotipi suddivisi in 3 cluster. Due pulsotipi sono risultati prevalenti raggruppando rispettivamente il 57,4% e il 21,3% dei ceppi isolati. L’analisi dei profili PFGE non ha rilevato relazioni tra pulsotipo e tipo di formaggio, ditta produttrice o punto vendita. La valutazione della distribuzione temporale dei pulsotipi ha messo in evidenza la presenza di un profilo persistente durante tutto il periodo di studio, ad eccezione dei mesi di agosto e settembre in cui è stato rilevato un pulsotipo diverso. Pertanto l’indagine ha permesso di rilevare la variabilità nel tempo della prevalenza di alcuni specifici pulsotipi che ha fatto ipotizzare l’intervento di fattori che hanno influenzato le dinamiche di contaminazione di questi prodotti. Studi su larga scala potrebbero contribuire al chiarimento di tale fenomeno.

  11. Cooperativity in virus neutralization by human monoclonal antibodies to two adjacent regions located at the amino terminus of hepatitis C virus E2 glycoprotein

    DEFF Research Database (Denmark)

    Keck, Zhenyong; Wang, Wenyan; Wang, Yong

    2013-01-01

    A challenge for hepatitis C virus (HCV) vaccine development is defining conserved epitopes that induce protective antibodies against this highly diverse virus. An envelope glycoprotein (E2) segment located at amino acids (aa) 412 to 423 contains highly conserved neutralizing epitopes. While...... at higher concentrations. However, the overall effect was additive neutralization. A similar pattern was observed when these antibodies were combined to block E2 binding to the HCV coreceptor, CD81. These findings demonstrate that both of these E2 regions participate in epitopes mediating virus...... (HCVcc) with various activities. Although nonneutralizing HC33 HMAbs were isolated, they had lower binding affinities than neutralizing HC33 HMAbs. These antibodies could be converted to neutralizing antibodies by affinity maturation. Unidirectional competition for binding to E2 was observed between HC33...

  12. Acordos bilaterais de comércio como estratégia de inserção regional e internacional do Chile Bilateral trade agreements as Chile's strategy for regional and international insertion

    Directory of Open Access Journals (Sweden)

    Renata Rossetto Lopes

    2010-12-01

    Full Text Available O trabalho analisa a mudança na estratégia de inserção regional e internacional do Chile no começo dos anos 1990, com ênfase em acordos comerciais bilaterais, depois de ter praticado a abertura comercial generalizada desde meados da década de 1970. A opção por acordos bilaterais foi adotada pelo primeiro governo democrático, como parte da orientação de manter e aprofundar a abertura externa empreendida pela ditadura, e conseguiu ampliar as vendas externas e diversificar produtos e destinos. As exportações têm papel decisivo na economia chilena, aberta e pequena, e os 24 acordos bilaterais de comércio com diferentes países e regiões, além de outros em negociação, podem ser explicados pelo esgotamento das possibilidades de ampliar o comércio por meio de reduções adicionais da tarifa externa unilateral, hoje em 6% para quase todos os produtos. A formação de uma rede de acordos bilaterais ampla e diversificada, contudo, tem também interesses políticos, estratégicos e de segurança em relação a vizinhos e a países próximos, além de evitar que o Chile precise se integrar, como membro pleno, a blocos regionais para garantir seus interesses, o que amplia as possibilidades de lidar com diferentes e importantes parceiros no âmbito internacional.The paper analysis the change of Chile's regional and international strategy of insertion through bilateral trade agreements in the beginning of the 90s, after a generalized trade opening since the middle of the 70s. The bilateral trade agreements strategy was set up by the democratic governments as part of the direction of maintaining and deepening the unilateral trade liberalization undertaken by the dictatorship, enlarging exports and diversifying products and markets. Exports have a decisive role in Chile's economy, open and small. The 24 bilateral trade agreements already signed with different countries and regions (besides others under negotiation can be explained by the

  13. Época de nascimento sobre a composição regional e tecidual da carcaça de cordeiros da raça Texel Birth season on regional and tissue carcass composition in Texel breed lambs

    Directory of Open Access Journals (Sweden)

    Gilson de Mendonça

    2008-06-01

    Full Text Available Foram avaliados os efeitos de épocas alternativas de nascimento sobre a composição regional e tecidual da carcaça em ovinos. Quarenta e nove cordeiros machos não-castrados da raça Texel, nascidos em duas épocas (agosto e novembro, foram mantidos em regime de pastagem e abatidos com média de idade de 129 e 164 dias, respectivamente. Previamente aos abates foi feita a avaliação da produção forrageira do campo pelo método Botanal. Foram verificadas melhores condições forrageiras para os cordeiros nascidos em agosto, que apresentaram maior peso e proporção na maioria dos cortes, assim como menor proporção de músculo na paleta e perna; apresentando maior conteúdo de tecido adiposo na maioria dos cortes da carcaça. Para os cordeiros nascidos em novembro, ocorreu maior relação músculo:gordura e músculo:osso na paleta e na perna, assim como maior relação músculo:gordura no costilhar. As condições nutricionais são responsáveis pelas diferenças nos pesos e rendimentos dos cortes, assim como na composição tecidual da carcaça, em cordeiros mantidos em regime de pasto, viabilizando o uso de época alternativa de nascimentos para incrementar a oferta de animais para o abate.The effect of alternative birth season on regional and tissue carcass composition of sheep was evaluated. Forty nine (49 Texel intact male lambs, born in two seasons (August and November, were kept under grazing and slaughtered with an average age of 129 and 164 days, respectively. Prior to slaughter forage production was measured using Botanal method. Lambs born in August had more favorable forage conditions, showing higher body weight and proportion in the majority of cuts, as well as lower proportion of shoulder and leg muscles showing higher adipose tissue content in the majority of carcass cuts. For lambs born in November, a higher muscle:fat and muscle:bone rate in shoulder and leg, as well as a higher ribcut muscle:fat rate. Nutritional

  14. Meaurement of the target single-spin asymmetry in quasi-elastic region from the reaction {sup 3}He{up_arrow}(e,e')

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yawei [Rutgers

    2013-10-01

    A measurement of the inclusive target single-spin asymmetry has been performed using the quasi-elastic {sup 3}He{up_arrow}(e,e') reaction with a vertically polarized {sup 3}He target at Q{sup 2} values of 0.13, 0.46 and 0.97 GeV{sup 2}. This asymmetry vanishes under the one photon exchange assumption. But the interference between two-photon exchange and one-photon exchange gives rise to an imaginary amplitude, so that a non-zero A{sub y} is allowed. The experiment, conducted in Hall A of Jefferson Laboratory in 2009, used two independent spectrometers to simultaneously measure the target single-spin asymmetry. Using the effective polarization approximation, the neutron single-spin asymmetries were extracted from the measured {sup 3}He asymmetries. The measurement is to establish a non-vanishing A{sub y}. Non-zero asymmetries were observed at all Q{sup 2} points, and the overall precision is an order of magnitude improved over the existing proton data. The data provide new constraints on Generalized Parton Distribution (GPD) models and new information on the dynamics of the two-photon exchange process.

  15. Angular analysis of the $B^0 \\to K^{*0} e^+ e^-$ decay in the low-$q^2$ region at LHCb

    CERN Multimedia

    Borsato, Martino

    2015-01-01

    An angular analysis of the $B^0 \\rightarrow K^{*0} e^+ e^-$ decay is performed using a data sample, corresponding to an integrated luminosity of 3.0${\\mbox {fb}^{-1}}$, collected by the LHCb experiment in $pp$ collisions at centre-of-mass energies of 7 and 8 TeV during 2011 and 2012. For the first time several observables are measured in the dielectron mass squared ($q^2$) interval between 0.002 and 1.120${\\mathrm{\\,Ge\\kern -0.1em V^2\\!/}c^4}$. The angular observables $F_{\\mathrm{L}}$ and $A_{\\mathrm{T}}^{\\mathrm{Re}}$ which are related to the \\Kstarz polarisation and to the lepton forward-backward asymmetry, are measured to be $F_{\\mathrm{L}}= 0.16 \\pm 0.06 \\pm0.03$ and $A_{\\mathrm{T}}^{\\mathrm{Re}} = 0.10 \\pm 0.18 \\pm 0.05$, where the first uncertainty is statistical and the second systematic. The angular observables $A_{\\mathrm{T}}^{(2)}$ and $A_{\\mathrm{T}}^{\\mathrm{Im}}$ which are sensitive to the photon polarisation in this $q^2$ range, are found to be $A_{\\mathrm{T}}^{(2)} = -0.23 \\pm 0.23 \\pm...

  16. Processamento do queijo coalho regional empregando leite pasteurizado e cultura lática endógena Manufacture of regional coalho type cheese by using pasteurized and standardized cow milk added with endogenous lactic acid culture

    Directory of Open Access Journals (Sweden)

    José Fernando Mourão Cavalcante

    2007-03-01

    Full Text Available O objetivo deste trabalho foi estabelecer uma proposta para o processamento do queijo Coalho regional seguindo-se os procedimentos adequados para a obtenção de um produto final de qualidade. Empregou-se leite de vaca padronizado e pasteurizado e culturas láticas endógenas. Foram isoladas, identificadas e caracterizadas culturas láticas endógenas de leite de vaca cru e de queijos Coalho artesanais. Algumas culturas foram avaliadas para a fabricação do queijo Coalho, seguindo-se o fluxograma de fabricação estabelecido neste estudo. O produto final foi submetido a análises físico-químicas, teste de aceitação e teste de fritura. Os resultados obtidos mostraram que é viável a padronização do produto tradicional, proporcionando redução de custos, qualidade microbiológica e a manutenção das características sensoriais do queijo Coalho regional, com o uso de culturas láticas nacionais.The main objective of this work is to propose a manufacturing procedure to make a safe artisan Coalho type cheese. Pasteurized and standardized cow´s milk added with endogenous lactic acid culture was used in the procedure. Endogenous lactic cultures were identified and characterized after being isolated from raw cow´s milk and artisan cheeses. The selected cultures were used in the manufacturing procedure designed for Coalho type cheese. Cheese made with added endogenous lactic acid culture underwent physic-chemical analysis, sensory acceptance and fritter tests. Results showed that it is feasible to make such cheese in a standardized process, with improved microbiological quality, keeping sensory properties of traditional cheese made with raw milk and a reduced cost using suppression on imports of starter cultures.

  17. Interfaces da gestão ambiental urbana e gestão regional: análise da relação entre Planos Diretores Municipais e Planos de Bacia Hidrográfica

    Directory of Open Access Journals (Sweden)

    Renata Bovo Peres

    2013-12-01

    Full Text Available Este artigo relata uma pesquisa que discute como a questão ambiental vem sendo tratada nos instrumentos e práticas de gestão localizadas em dois recortes territoriais: municípios e bacias hidrográficas. Foi analisada a relação da dimensão ambiental com a gestão regional e municipal, por meio dos instrumentos Planos de Bacia Hidrográfica e Planos Diretores Municipais, tendo como locus a Unidade de Gerenciamento de Recursos Hídricos Tietê-Jacaré do Estado de São Paulo. Os objetos de pesquisa selecionados foram o Plano de Bacia Hidrográfica Tietê-Jacaré e os Planos Diretores de Araraquara e São Carlos. A pesquisa abordou as seguintes categorias de análise: unidades de planejamento, instrumentos ambientais contidos no Plano de Bacia e nos Planos Diretores, instâncias de gestão e grau de influência entre os planos analisados. O método se pautou em levantamentos, análises bibliográficas e documentais, entrevistas semiestruturadas e questionários. Os resultados obtidos apontaram que o Plano de Bacia Hidrográfica ainda apresenta lacunas e dificuldades para uma atuação mais ampliada. Não reconhece os conflitos de uso da terra e de organização territorial como uma vulnerabilidade que precisa ser enfrentada. Mostraram, ainda, que os Planos Diretores Municipais concentram-se na aplicação dos instrumentos voltados ao parcelamento e ao zoneamento urbano. Nesses planos, as condições e os aspectos ambientais e regionais se apresentam como uma temática periférica e pouco articulada com as demais políticas. As análises procuraram demonstrar a complexa relação entre políticas, instrumentos e instâncias de planejamento e gestão, explicitando os obstáculos que dificultam a aplicação do conceito de gestão territorial integrada.

  18. Satisfação no serviço público: um estudo na Superintendência Regional do Trabalho e Emprego no Ceará

    Directory of Open Access Journals (Sweden)

    Isac de Freitas Brandão

    Full Text Available A satisfação no trabalho é vista como um aspecto que, quando presente, motiva os empregados, e afeta positivamente a produtividade destes. Nesta perspectiva, o presente estudo buscou identificar os fatores preponderantes para satisfação no trabalho na Superintendência Regional do Trabalho e Emprego (SRTE/CE, à luz da teoria bifatorial de Herzberg (1997. Foi realizada uma survey com três grupos distintos de agentes públicos: auditores fiscais do trabalho, servidores administrativos e estagiários. Os dados foram analisados por meio de métodos quantitativos e análise de conteúdo. O questionário continha uma escala de satisfação tipo Likert de cinco pontos, versando sobre o nível de satisfação dos pesquisados, com cinco fatores motivacionais e seis fatores higiênicos, além de duas perguntas abertas sobre outros aspectos relativos à satisfação ou insatisfação dos respondentes com o trabalho. Os resultados revelaram que os fatores motivacionais que predominaram na geração da satisfação nos três grupos investigados foram a realização profissional, as atividades desempenhadas e a responsabilidade atribuída. Entre os fatores higiênicos, os servidores e estagiários do Ministério do Trabalho e Emprego mostraram-se mais satisfeitos, de forma geral, com a supervisão e com os relacionamentos interpessoais. Estes resultados corroboram pesquisas anteriores realizadas em outras entidades governamentais. Adicionalmente, análises de correlação e testes não paramétricos mostraram que as características do perfil do respondente podem influenciar na satisfação com alguns fatores motivacionais e higiênicos analisados.

  19. Nucleotide sequence of the Escherichia coli pyrE gene and of the DNA in front of the protein-coding region

    DEFF Research Database (Denmark)

    Poulsen, Peter; Jensen, Kaj Frank; Valentin-Hansen, Poul

    1983-01-01

    leader segment in front of the protein-coding region. This leader contains a structure with features characteristic for a (translated?) rho-independent transcriptional terminator, which is preceded by a cluster of uridylate residues. This indicates that the frequency of pyrE transcription is regulated......Orotate phosphoribosyltransferase (EC 2.4.2.10) was purified to electrophoretic homogeneity from a strain of Escherichia coli containing the pyrE gene cloned on a multicopy plasmid. The relative molecular masses (Mr) of the native enzyme and its subunit were estimated by means of gel filtration...

  20. Influência regional no consumo precoce de alimentos diferentes do leite materno em menores de seis meses residentes nas capitais brasileiras e Distrito Federal

    OpenAIRE

    Saldiva,Silvia Regina Dias Medici; Venancio,Sonia Isoyama; Gouveia,Ana Gabriela Cepeda; Castro,Ana Lucia da Silva; Escuder,Maria Mercedes Loureiro; Giugliani,Elsa Regina Justo

    2011-01-01

    Objetivou-se avaliar a influência regional no consumo precoce de alimentos diferentes do leite materno em menores de seis meses residentes nas capitais brasileiras. Analisaram-se dados de 18.929 crianças da II Pesquisa de Prevalência de Aleitamento Materno nas Capitais Brasileiras - 2008. As frequências do consumo de chá, sucos, leite artificial e mingau/papa foram calculadas para as capitais das cinco regiões brasileiras. Curvas do consumo foram obtidas pela análise de logitos e estimativas ...

  1. Tecnologia, especialização regional e produtividade: um estudo da pecuária leiteira em Minas Gerais

    Directory of Open Access Journals (Sweden)

    Mauro Borges Lemos

    2003-01-01

    Full Text Available Este trabalho pretende estabelecer um comparativo entre algumas microrregiões mineiras produtoras de leite, enfocando, sobretudo, características tecnológicas e de especialização. Trabalha-se com a idéia de que estas variáveis explicam em grande medida o diferencial de produção e produtividade do setor leiteiro, sendo importante o seu entendimento dentro do contexto de intensas mudanças as quais o setor vem passando nos últimos anos no Brasil. Desenvolvendo um estudo de dimensão espacial, pretende-se traçar um perfil da atividade em Minas Gerais, apontando os principais "gargalos" para o seu desenvolvimento e as perspectivas para a redução das desigualdades no setor.

  2. A resposta das politécnicas finlandesas aos desafios das políticas de inovação e de desenvolvimento regional

    Directory of Open Access Journals (Sweden)

    Anu Lyytinen

    Full Text Available Este trabalho apresenta uma análise do desenvolvimento recente de uma parte do ensino superior na Finlândia. Seu objetivo é analisar como as politécnicas finlandesas reagiram às novas exigências para que se tornassem responsivas às necessidades regionais e como elas construíram as competências necessárias para esse engajamento regional. O quadro de referência teórica central são os elementos de mudança institucional descritos por Burton Clark (1998 em sua análise sobre as universidades empreendedoras. Em particular, o artigo focaliza os canais e interfaces que essas instituições estabeleceram com outros atores no âmbito regional.

  3. Análisis de convergencia económica en el interior de Chiapas: municipios, regiones e inconsistencias aparentes

    OpenAIRE

    López Arévalo, Jorge Alberto; Peláez Herreros, Óscar

    2012-01-01

    The data of annual per capita income estimated by the United Nations Development Programme (UNDP) for the municipal human development index in Mexico shows that, in Chiapas, during the period 2000-2005, there was a strong convergence at the municipal level while there was no regional convergence. To explain this apparent inconsistency, the article «Regression towards mediocrity in hereditary stature», published by Galton in 1886, is examined, concluding that the clustering level of the data (...

  4. A arquitetura e o planejamento urbano-regional emface do processo de mundialização

    OpenAIRE

    Alessandro Ventura; Carlos Eduardo Zahn; José Luiz Ronca Caruso

    2003-01-01

    1. Main characteristics of the current process ofglobalization; instability created by the formation ofthe global society; changes in the relations of space-time in architecture and urbanism; 2. The physical planning in the face of changes;contributions of four Chartes Atenas, LaTourrette, Andes and UIA / Beijing-, of geographersand economists for the field of regional planning andarchitecture; the current changes and theirconsequences in the process of physical planning; 3. The modular prod...

  5. Regional energy supply in 1996/1997. Progress report of the working pool of regional power supply companies (ARE e.V.); Regionale Energieversorgung 1996-1997. Taetigkeitsbericht der Arbeitsgemeinschaft regionaler Energieversorgungs-Unternehmen - ARE - e.V

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-04-01

    Generally speaking the present report deals with the regional power supply as part of the whole economy. In this connection it also addresses issues of economic development. The following topics are covered in its report on the activities of ARE since the annual meeting of 1996; energy policy, regional supply in the new Laender, European common market for electricity and natural gas, energy-economic law, special provisions under cartel law concerning public utilities. The report concludes with a description of the organisation of ARE (tasks and aims, members, executive board, management, committees, headquarters). (RHM) [Deutsch] Gegenstand des Berichtes ist zunaechst die regionale Energieversorgung im Rahmen der Gesamtwirtschaft. Dabei wird sowohl auf die wirtschaftliche Entwicklung als auf die regionale Energieversorgung eingegangen. Anschliessend wird ein Ueberblick ueber die Taetigkeit des ARE seit der Jahrestagung 1996 gegeben. Dabei werden Aktivitaeten in den Bereichen Energiepolitik, Regionalversorgung in den neuen Bundeslaendern, europaeischer Binnenmarkt fuer Elektrizitaet und Gas, Energiewirtschaftsrecht sowie kartellrechtlicher Ausnahmebereich Versorgungswirtschaft behandelt. Abschliessend wird die Organisation der ARE (Aufgaben und Ziele, Mitglieder, Vorstand, Geschaeftsfuehrung, Ausschuesse, Geschaeftsstelle) beschrieben. (RHM)

  6. Regional energy supply in 1994/1995. Progress report of the working pool of regional power supply companies (ARE e.V.); Regionale Energieversorgung 1994/1995. Taetigkeitsbericht der Arbeitsgemeinschaft regionaler Energieversorgungs-Unternehmen - ARE - e.V

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-04-01

    Generally speaking the present report deals with the regional power supply as part of the whole economy. In this connection it also addresses issues of economic development. The following topics are covered in its report on the activities of ARE since the annual meeting of 1994; energy policy, regional supply in the new Laender, European common market for electricity, energy-economic law, special provisions under cartel law concerning public utilities. The report concludes with a description of the organisation of ARE (tasks and aims, members, executive board, management, committees, headquarters). (RHM) [Deutsch] Gegenstand des Berichtes ist zunaechst die regionale Energieversorgung im Rahmen der Gesamtwirtschaft. Dabei wird sowohl auf die wirtschaftliche Entwicklung als auf die regionale Energieversorgung eingegangen. Anschliessend wird ein Ueberblick ueber die Taetigkeit des ARE seit der Jahrestagung 1994 gegeben. Dabei werden Aktivitaeten in den Bereichen Energiepolitik, Regionalversorgung in den neuen Bundeslaendern, europaeischer Binnenmarkt fuer Elektrizitaet, Energiewirtschaftsrecht sowie kartellrechtlicher Ausnahmebereich Versorgungswirtschaft behandelt. Abschliessend wird die Organisation der ARE (Aufgaben und Ziele, Mitglieder, Vorstand, Geschaeftsfuehrung, Ausschuesse, Geschaeftsstelle) beschrieben. (RHM)

  7. E-Business, The impact of the Regional Government Development (APBD) on Information and Communication Development in Indonesia

    Science.gov (United States)

    Setiawan, M. I.; Hasyim, C.; Kurniasih, N.; Abdullah, D.; Napitupulu, D.; Rahim, R.; Sukoco, A.; Dhaniarti, I.; Suyono, J.; Sudapet, IN; Nasihien, RD; Wulandari, DAR; Reswanda; Mudjanarko, SW; Sugeng; Wajdi, MBN

    2018-04-01

    The decline of development delived from natural resources in several regions in Indonesia requires local governments to make a breakthrough in increasing revenues beyond natural resources, including through increased revenue in the field of information technology. The purpose of this study is to analyze the impact of the regional government development (APBD) on information and communication development in Indonesia. By using correlational research, it is known that all of APBD sub variables have a high correlation in increasing Gross Regional Domestic Product (GRDP) of Information and Communication in Indonesia, only sub-variable of surplus/deficit development, unexpected development sub-variable, subvariable of development aid to province/regency/city and village government, and sub-variable of development special allocations that have not a significant correlation to increase of GRDP of Information and Communication in Indonesia. There is 86,7% of APBD variable influence the increase of GRDP of Information and Communication, while the increase of 15,3% of Information and Communication GRDP influenced by other factors aside from APBD. It shows the strong impact of APBD on increasing GRDP of Information and Communication

  8. ¿Mercosur o Alca? Clase dominante, gobierno e inserción regional en los inicios del Kirchnerismo

    Directory of Open Access Journals (Sweden)

    Julián Kan

    2013-10-01

    Full Text Available El objetivo de este trabajo es analizar la relación entre gobierno, corporaciones empresarias de la clase dominante y los proyectos MERCOSUR y ALCA en los inicios del gobierno de Kirchner. La hipótesis principal es que los cambios en la inserción regional de Argentina desde 2003 (reconstrucción del MERCOSUR y rechazo al ALCA, tuvieron entre una de sus causas a las acciones de corporaciones como la Unión Industrial Argentina (UIA y la Sociedad Rural Argentina (SRA. Como afirma Katz (2006 aquella reconfiguración regional, además de estar influenciada por las protestas sociales antineoliberales, también respondió a la demanda de una diferente inserción regional por parte de las clases dominantes locales. Mediante el análisis de la prensa escrita y de documentación de las corporaciones, observaremos los posicionamientos sobre el ALCA y el MERCOUSR, el tipo de intervención del gobierno que reclaman y por qué apoyan o rechazan las negociaciones entre 2003 y 2004, en la reunión de la Ronda Doha de Cancún de la Organización mundial de Comercio (OMC y en las Minicumbres del ALCA de Miami y Puebla, donde quedaron trabadas las negociaciones del ALCA y se produjo la reorientación del MERCOSUR

  9. Electromobility in metropolitan regions. The case study MINI E Berlin powered by Vattenfall; Elektromobilitaet in Metropolregionen. Die Feldstudie MINI E Berlin powered by Vattenfall

    Energy Technology Data Exchange (ETDEWEB)

    Krems, Josef F.; Weinmann, Oliver; Weber, Julian; Westermann, Dirk; Albayrak, Sahin (eds.)

    2013-04-01

    One promising option of the reduction of the emission of greenhouse gases and the promotion of the climate protection is the utilization of electric-powered vehicles. The customer acceptance and practical suitability of electric-powered vehicles are essential factors of success which are investigated within the Berlin field test 'MINI E 1.0 powered by Vattenfall' from the perspective of energy industry, vehicle manufacturer and the science. Beside the hurdles up to the establishment in the mass market, it is shown how the users with aspects specific for electric-powered vehicles interact, and how the controlled loading facilitates the optimal integration of wind power. The comprehensive collection of subjective and objective data as well as detailed information on the conception of the case study complete the contribution under consideration.

  10. Meteor radar measurements of MLT winds near the equatorial electro jet region over Thumba (8.5° N, 77° E: comparison with TIDI observations

    Directory of Open Access Journals (Sweden)

    S. R. John

    2011-07-01

    Full Text Available The All-Sky interferometric meteor (SKYiMET radar (MR derived winds in the vicinity of the equatorial electrojet (EEJ are discussed. As Thumba (8.5° N, 77° E; dip lat. 0.5° N is under the EEJ belt, there has been some debate on the reliability of the meteor radar derived winds near the EEJ height region. In this regard, the composite diurnal variations of zonal wind profiles in the mesosphere-lower thermosphere (MLT region derived from TIMED Doppler Interferometer (TIDI and ground based meteor radar at Thumba are compared. In this study, emphasis is given to verify the meteor radar observations at 98 km height region, especially during the EEJ peaking time (11:00 to 14:00 LT. The composite diurnal cycles of zonal winds over Thumba are constructed during four seasons of the year 2006 using TIDI and meteor radar observations, which showed good agreement especially during the peak EEJ hours, thus assuring the reliability of meteor radar measurements of neutral winds close to the EEJ height region. It is evident from the present study that on seasonal scales, the radar measurements are not biased by the EEJ. The day-time variations of HF radar measured E-region drifts at the EEJ region are also compared with MR measurements to show there are large differences between ionospheric drifts and MR measurements. The significance of the present study lies in validating the meteor radar technique over Thumba located at magnetic equator by comparing with other than the radio technique for the first time.

  11. Calibração regional e local da equação de Hargreaves para estimativa da evapotranspiração de referência Regional and local calibration of Hargreaves equation for estimating reference evapotranspiration

    Directory of Open Access Journals (Sweden)

    Diego Simões Fernandes

    2012-06-01

    Full Text Available A equação de Penman-Monteith FAO-56 (EToPM tem sido recomendada pela FAO, Organização para a Alimentação e Agricultura das Nações Unidas (ONU, como padrão para estimar a evapotranspiração de referência (ETo. Essa equação requer muitas variáveis que não estão disponíveis na maioria das estações meteorológicas no Brasil central. Por outro lado, a equação de Hargreaves é considerada simples e demanda somente dados de temperatura máxima e mínima para estimar a ETo. Entretanto, essa equação requer um ajuste local. Esse estudo analisa a possibilidade de utilizar a equação de Hargreaves ajustada para estimar a ETo no estado de Goiás. Para isso, os parâmetros empíricos, HC (coeficiente empírico de Hargreaves e HE (expoente empírico de Hargreaves, da equação de Hargreaves foram ajustados considerando dois processos, ajuste local (HGR - Hargreaves ajuste local e ajuste regional (HGL - Hargreaves ajuste regional. Para o HGL, os parâmetros empíricos foram ajustados para cada estação meteorológica. Já, para o HGR, os parâmetros empíricos foram ajustados considerando conjuntamente os dados de todas as estações meteorológicas. A equação de Hargreaves ajustada para ambos os processos, local e regional, apresentou valores de ERQM de 17,95 e 21,93%, respectivamente, considerando o conjunto total de dados climáticos. A equação de Hargreaves ajustada localmente ou regionalmente é uma opção para estimar os valores diários de ETo no Estado de Goiás em locais em que a disponibilidade de dados climáticos é limitada.The FAO-56 Penman-Monteith equation (EToPM has been recommended by the Food and Agriculture Organization (FAO of the United Nations as the standard equation for estimating reference evapotranspiration (ETo. The FAO-56 PM equation requires numerous weather data that are not available in most of the stations of Brazil central. On the other hand, the Hargreaves equation is a more simple equation for

  12. Multiple drug resistance patterns in various phylogenetic groups of uropathogenic E.coli isolated from Faisalabad region of Pakistan

    Directory of Open Access Journals (Sweden)

    Saira Bashir

    2011-12-01

    Full Text Available The objective of this work was the phylogenetic characterization of local clinical isolates of uropathogenic E. coli with respect to drug resistance. A total of 59 uropathogenic E. coli responsible for community acquired urinary tract infections were included in this study. A triplex PCR was employed to segregate each isolate into four different phylogenetic groups (A, B1, B2 and D. Drug resistance was evaluated by disc diffusion method. The drugs used were ampicillin, aztreonam, cefixime, cefoperazone, ceftriaxone, cephradine among β-lactam group; amikacin, gentamicin, and streptomycin among aminoglycosides; nalidixic acid and ciprofloxacin from quinolones; trimethoprim-sulfomethoxazole, and tetracycline. Among 59 uropathogenic E. coli isolates majority belonged to phylogenetic group B2 (50% where as 19% each belonged to groups A and B1, and 12% to group D. All the isolates were multiple drug resistant (MDR. Most effective drugs against Group A, B1, and B2 were gentamicin, amikacin and cefixime; ceftriaxone and quinolones; and ceftriaxone and amikacin, respectively. Group D isolates were found to be highly resistant to all drugs. Our results have shown emergence of MDR isolates among uropathogenic E. coli with dominance of phylogenetic group B2. However, it was found that group D isolates were though less frequent, more drug resistant as compared with group B2. Groups A and B1 were relatively uncommon. Amikacin, ceftriaxone and gentamicin were the most effective drugs in general.

  13. Modelos nacionais e regionais de família no pensamento social brasileiro National and Regional Family Patterns in Brazilian Social Thought

    Directory of Open Access Journals (Sweden)

    CANDICE VIDAL E SOUZA

    2001-01-01

    Full Text Available As revisões sobre os estudos clássicos de família no Brasil convergem na crítica ao patriarcalismo como modelo genérico e fixo de descrição dessa instituição, propondo que a família brasileira era uma pluralidade dispersa de experiências. Sugerimos que já nas narrativas ensaísticas sobre a identidade nacional existem modelos plurais de família brasileira, diversificados em termos da compreensão dos arranjos locais de relações familiares. Com esse objetivo, relemos, sob o eixo família-nação-região, dois conjuntos de ensaístas significativos para a construção de identidades regionais particulares (primeiro, Alfredo Ellis Jr. e Cassiano Ricardo; segundo, Alceu Amoroso Lima e Sylvio de Vasconcellos, pensadores/produtores de visões de São Paulo e de Minas Gerais, respectivamente, enquanto culturas e sociedades em grande parte caracterizadas por suas experiências de organização familiar própria.Revisions of classical studies of the family in Brazil agree in criticizing patriarchalism as a general and fixed model describing this institution, arguing that the Brazilian family was a plurality of dispersed experiences. We suggest that in the essay narratives of national identity there are already plural models of the Brazilian family, which are diversified according to local arrangements of family relations. Considering the themes family-nation-region, we review the work of two groups of important essayists on the construction of particular regional identities: Alfredo Ellis Jr. e Cassiano Ricardo; Alceu Amoroso Lima e Sylvio de Vasconcellos. We argue that these essayists articulated visions of São Paulo and Minas Gerais as cultures and societies characterized in a significant way by experiences of a proper family organization.

  14. Association between the MHC gene region and variation of serum IgE levels against specific mould allergens in the horse

    Directory of Open Access Journals (Sweden)

    Curik Ino

    2003-06-01

    Full Text Available Abstract To investigate whether the equine major histocompatibility complex (MHC gene region influences the production of mould-specific immunoglobulin E antibodies (IgE, alleles of the equine leukocyte antigen (ELA-A locus and three microsatellite markers (UM-011, HTG-05 and HMS-42 located on the same chromosome as the equine MHC were determined in 448 Lipizzan horses. Statistical analyses based on composite models, showed significant associations of the ELA-A and UM-011 loci with IgE titres against the recombinant Aspergillus fumigatus 7 antigen (rAsp f 7. UM-011 was also significantly associated with IgE titres against the recombinant Aspergillus fumigatus 8 antigen (rAsp f 8. In addition to the loci mentioned above, the MHC class II DQA and DRA loci were determined in 76 Lipizzans from one stud. For IgE levels against rAsp f 7, the composite model showed the strongest association for DQA (P rAsp f 8 specific IgE levels, similarly to the results found with all 448 horses, the strongest association was found with UM-011 (P = 0.01, which is closely linked with the MHC class II DRB locus. These results suggest that the equine MHC gene region and possibly MHC class II loci, influence the specific IgE response in the horse. However, although the strongest associations were found with DQA and UM-011, this study did not distinguish if the observed effects were due to the MHC itself or to other tightly linked genes.

  15. Heavy metals and organic compounds contamination in soil from an e-waste region in South China.

    Science.gov (United States)

    Liu, Ming; Huang, Bo; Bi, Xinhui; Ren, Zhaofang; Sheng, Guoying; Fu, Jiamo

    2013-05-01

    Heavy metals and persistent organic pollutants polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (PBDEs) were analyzed in 34 surface soil samples collected from farmland and 7 soil or dust samples collected from the workshops in South China, where e-waste was dismantled using primitive techniques. The results show that Cd, Cu and Hg were the most abundant metals, in particular Cd pollution was serious in farmland soils, and the median concentrations in farmland soils were beyond the environmental quality standard for soils (China Grade II). A correlation between Cd, Cu, Zn, Pb and PCBs or PBDEs was significant indicating similar sources. Among the PCB congeners, high relative similarity was observed between the e-waste dump site soil (EW1) and Aroclor 1254, implying that the technical product Aroclor 1254 was one of the major sources of PCB contamination. High concentrations of PCBs in workshop dusts (D2 and D3) (1958 and 1675 μg kg(-1)) demonstrated that the workshops dismantling electrical wires and cables, electrical motors, compressors and aluminum apparatus containing PCBs in lubricants represent strong PCB emission sources to this area. Principal component analysis (PCA) and PBDE homologue patterns verify that farmland soils surrounding the e-waste recycling sites were enriched with lower brominated congeners, and the major source of PBDEs in dust samples might potentially be associated with the extensive use of deca-mix technical products as a flame retardant. The difference between e-waste soils, dusts and farmland soils can be observed in the PCA score plot of PCBs and PBDEs, and E-waste soils and dusts exhibited more diversity than farmland soils. Furthermore, a prediction of the particular kinds of pollution from different recycling activities through the analysis of each contamination and the connections between them was investigated.

  16. The development of the conditionally replication-competent adenovirus: replacement of E4 orf1-4 region by exogenous gene.

    Science.gov (United States)

    Nam, Jae-Kook; Lee, Mi-Hyang; Seo, Hae-Hyun; Kim, Seok-Ki; Lee, Kang-Huyn; Kim, In-Hoo; Lee, Sang-Jin

    2010-05-01

    Tumor or tissue specific replicative adenovirus armed with a therapeutic gene has shown a promising anti-cancer therapeutic modality. However, because the genomic packaging capacity is constrained, only a few places inside it are available for transgene insertion. In the present study, we introduce a novel strategy utilizing the early E4 region for the insertion of therapeutic gene(s). We constructed the conditionally replication-competent adenovirus (CRAd), Ad5E4(mRFP) by: (i) replacing the E4/E1a promoter by the prostate-specific enhancer element; (ii) inserting mRFP inside the E4orf1-4 deletion region; and (iii) sub-cloning enhanced green fluorescent protein controlled by cytomegalovirus promoter in the left end of the viral genome. Subsequently, we evaluated its replication abilities and killing activities in vitro, as well as its in vivo anti-tumor efficacy in CWR22rv xenografts. When infected with Ad5E4(mRFP), the number and intensity of the mRFP gene products increased in a prostate cancer cell-specific manner as designed, suggesting that the mRFP gene and E4orfs other than E4orf1-4 were well synthesized from one transcript via alternative splicing as the recombinant adenovirus replicated. As expected from the confirmed virus replication capability, Ad5E4(mRFP) induced cell lysis as potent as the wild-type adenovirus and effectively suppressed tumor growth when tested in the CWR22rv xenografts in nude mice. Furthermore, Ad5E4(endo/angio) harboring an endostatin-angiostatin gene in E4orf1-4 was able to enhance CRAd by replacing mRFP with a therapeutic gene. The approach employed in the present study for the insertion of a therapeutic transgene in CRAd should facilitate the construction of CRAd containing multiple therapeutic genes in the viral genome that may have the potential to serve as highly potent cancer therapeutic reagents. Copyright (c) 2010 John Wiley & Sons, Ltd.

  17. SU-E-T-104: An Examination of Dose in the Buildup and Build-Down Regions

    International Nuclear Information System (INIS)

    Tome, W; Kuo, H; Phillips, J

    2015-01-01

    Purpose: To examine dose in the buildup and build-down regions and compare measurements made with various models and dosimeters Methods: Dose was examined in a 30×30cm 2 phantom of water-equivalent plastic with 10cm of backscatter for various field sizes. Examination was performed with radiochromic film and optically-stimulated-luminescent-dosimeter (OSLD) chips, and compared against a plane-parallel chamber with a correction factor applied to approximate the response of an extrapolation chamber. For the build-down region, a correction factor to account for table absorption and chamber orientation in the posterior-anterior direction was applied. The measurement depths used for the film were halfway through their sensitive volumes, and a polynomial best fit curve was used to determine the dose to their surfaces. This chamber was also compared with the dose expected in a clinical kernel-based computer model, and a clinical Boltzmann-transport-equation-based (BTE) computer model. The two models were also compared against each other for cases with air gaps in the buildup region. Results: Within 3mm, all dosimeters and models agreed with the chamber within 10% for all field sizes. At the entrance surface, film differed in comparison with the chamber from +90% to +15%, the BTE-model by +140 to +3%, and the kernel-based model by +20% to −25%, decreasing with increasing field size. At the exit surface, film differed in comparison with the chamber from −10% to −15%, the BTE-model by −53% to −50%, the kernel-based model by −55% to −57%, mostly independent of field size. Conclusion: The largest differences compared with the chamber were found at the surface for all field sizes. Differences decreased with increasing field size and increasing depth in phantom. Air gaps in the buildup region cause dose buildup to occur again post-gap, but the effect decreases with increasing phantom thickness prior to the gap

  18. The socioeconomic scenario and opportunities for mature production regions; O cenario socioeconomico e oportunidades de desenvolvimento para regioes produtoras maduras

    Energy Technology Data Exchange (ETDEWEB)

    Reis, Andrea Campos; Lima, Regina Celia Palacio

    2009-07-01

    It is shown that production of oil and gas in mature fields provides good conditions for the economic and social development of the producing regions. This article presents the current social-economic scenery in areas of mature production. The authors provide a comparison between collected royalties and human development indicator in some countries with analysis of socio-economic data and comparison of results with and without the collection of royalties. Additionally, this papers offers a study of the socio-economic motivations for production in mature fields and describes several initiatives for improving living conditions for the local population. (author)

  19. Indústria e desenvolvimento regional: a trajetória da perfumarias Phebo em Belém

    OpenAIRE

    CHIACCHIO, Marcílio Alves

    2010-01-01

    O atual trabalho é a construção de um estudo cuja área de conhecimento se encontra nos fundamentos da história de empresas, tendo como estudo de caso a Perfumarias Phebo, uma empresa paraense, que se destacou no mercado de perfumaria nacional. O método da pesquisa consistiu no levantamento de informações arquivística referentes a implantação, trajetória histórica e evolução administrativa-financeira da Phebo, no período de 1936 a 1988, realizada a partir de informações disponibilizadas pela e...

  20. Da Região ao Território: uma análise estilizada sobre abordagens debates e novos desafios do desenvolvimento urbano-regional

    Directory of Open Access Journals (Sweden)

    Silvia Gorenstein

    2014-01-01

    Full Text Available O artigo procura entender as mudanças teóricas relacionadas à questão regional, que se altera de acordo com o ambiente ou momento histórico, econômico e político considerados. Assim, são analisados termos característicos desse campo do conhecimento, mais especificamente em relação ao maior uso de “território” em detrimento de “região” nas últimas décadas. São acompanhadas, ainda, as abordagens e as sucessivas ideias que vêm redefinindo-as. Enfatiza-se também a perspectiva regional nos países da América Latina e os futuros desafios na nova geopolítica mundial, pontuando algumas recomendações em relação à reformulação de estratégias e políticas.

  1. EDUCAÇÃO E ETNICIDADE NA REGIÃO DE SANTA CRUZ DO SUL- RS. EDUCATION AND ETHNICITY IN THE REGION OF SANTA CRUZ DO SUL - RS

    Directory of Open Access Journals (Sweden)

    Mozart Linhares da Silva

    2012-11-01

    Full Text Available O objetivo deste artigo é analisar as relações entre educação, etnicidade e mobilidade social em região de colonização alemã no Rio Grande do Sul, sobretudo em Santa Cruz do Sul, Brasil, cidade com forte discurso identitário germânico. Em que pese ser uma cidade caracterizada pelo germanismo, o que se constatou nas pesquisas até aqui realizadas, abrangendo os últimos seis anos, é que a região em questão possui significativa população de não-brancos, embora invisibilizada socialmente e excluída do processo de pertencimento identitário da comunidade regional. As pesquisas realizadas nas escolas municipais, estaduais e privadas na região de Santa Cruz do Sul permitem uma análise pontual das relações entre a educação e a imobilidade social, cujo resultado pode ser avaliado na dinâmica da visibilidade/invisibilidade identitária e processos de exclusão comunitário destes grupos, nomeadamente dos afrodescendentes.The objective of this article is to analyze the relations among education, ethnicity and social mobility in the region of German colonization in Rio Grande do Sul, and mainly in Santa Cruz do Sul, Brazil, a city with strong German identity speech. Taking into consideration that it is a city characterized by Germanism, what was observed in the researches accomplished until now, including the last six years, is that the region in question has a significant population of non-white people, though socially invisible and excluded from the identitary inclusion process of the region community. The researches that were carried out in the private and public – municipal and state – schools in the region of Santa Cruz do Sul permit sharp analysis of the relations between education and social immobility, which result can be evaluated in the identitary visibility/invisibility dynamic and processes of community exclusion of those groups, nominally of Afro-descendants.

  2. Rocket in situ observation of equatorial plasma irregularities in the region between E and F layers over Brazil

    Directory of Open Access Journals (Sweden)

    S. Savio Odriozola

    2017-03-01

    Full Text Available A two-stage VS-30 Orion rocket was launched from the equatorial rocket launching station in Alcântara, Brazil, on 8 December 2012 soon after sunset (19:00 LT, carrying a Langmuir probe operating alternately in swept and constant bias modes. At the time of launch, ground equipment operated at equatorial stations showed rapid rise in the base of the F layer, indicating the pre-reversal enhancement of the F region vertical drift and creating ionospheric conditions favorable for the generation of plasma bubbles. Vertical profiles of electron density estimated from Langmuir probe data showed wave patterns and small- and medium-scale plasma irregularities in the valley region (100–300 km during the rocket upleg and downleg. These irregularities resemble those detected by the very high frequency (VHF radar installed at Jicamarca and so-called equatorial quasi-periodic echoes. We present evidence suggesting that these observations could be the first detection of this type of irregularity made by instruments onboard a rocket.

  3. In vitro neutralization of HCV by goat antibodies against peptides encompassing regions downstream of HVR-1 of E2 glycoprotein.

    Science.gov (United States)

    Tabll, Ashraf A; Atef, Khaled; Bader El Din, Noha G; El Abd, Yasmine S; Salem, Ahmed; Sayed, Ahmed A; Dawood, Reham M; Omran, Moataza H; El-Awady, Mostafa K

    2014-01-01

    This article aims at testing several in vitro systems with various viral sources and cell lines for propagation of HCV to evaluate goat antibodies raised against three E2 epitopes in viral neutralization experiments. Four human cell lines (Huh-7, Huh-7.5, HepG2, and CaCo2) were tested using two different HCV viral sources; Genotype 4 infected sera and J6/JFH HCV cc particles. Neutralization capacity of goat Abs against conserved E2 epitopes; p412 (a.a 412-419), p517 (a.a 517-531), and p430 (a.a 430-447) were examined in the above mentioned in vitro systems. Although infection with patients' sera seems to mimic the in vitro situation, it has limited replication rates as compared with HCV cc particularly in Huh7.5 cells. Non-HCV adapted Huh-7 cells were also found susceptible for transfection with J6/JFH virus but at much slower kinetics. The results of the neutralization assay showed that anti p412 and anti p517 were highly neutralizing to HCVcc. Our data demonstrate that antibodies directed against the viral surface glycoprotein E2 reduced the infectivity of the J6/JFH virus and are promising agents for immunotherapy and HCV vaccine development.

  4. Microclones derived from the mouse chromosome 7 D-E bands map within the proximal region of the c14CoS deletion in albino mutant mice

    International Nuclear Information System (INIS)

    Toenjes, R.R.W.; Weith, A.; Rinchik, E.M.; Winking, H.; Carnwath, J.W.; Kaliner, B.; Paul, D.

    1991-01-01

    A group of radiation-induced perinatal-lethal deletions that include the albino (c) locus on mouse chromosome 7 causes failure of expression of various hepatocyte-specific genes when homozygous. The transcription of such genes could be controlled in trans by a regulatory gene(s) located within the proximal region of the C14CoS deletion. To identify this potential regulatory gene, a microclone library was established from microdissected D and E bands of chromosome 7. Three nonoverlapping microclones (E305, E336B, and E453B) hybridizing with wildtype but not with C14CoS/C14CoS DNA were isolated. E336B represents a single-copy DNA fragment, whereas E305 and E453B hybridized with 3 and 10 EcoRI DNA restriction fragments, respectively. All fragments map exclusively within the deletion. The microclones hybridized to DNA of viable C6H/C14CoS deletion heterozygotes but not to DNA of homozygotes for the lethal mutation c10R75M, which belongs to the same complementation group as c14CoS. DNA of viable homozygous mutant C62DSD, which carries a deletion breakpoint proximal to that of c6H, hybridized only with E453B. This microclone identified 6 EcoRI restriction fragments in C62DSD/C62DSD DNA. The results demonstrate that of the isolated microclones, E453B identifies a locus (D7RT453B) that maps closest to the hsdr-1 (hepatocyte-specific developmental regulation) locus, which maps between the proximal breakpoints of deletions c10R75M and c62DSD

  5. Regional variation in the prevalence of E. coli O157 in cattle: a meta-analysis and meta-regression.

    Science.gov (United States)

    Islam, Md Zohorul; Musekiwa, Alfred; Islam, Kamrul; Ahmed, Shahana; Chowdhury, Sharmin; Ahad, Abdul; Biswas, Paritosh Kumar

    2014-01-01

    Escherichia coli O157 (EcO157) infection has been recognized as an important global public health concern. But information on the prevalence of EcO157 in cattle at the global and at the wider geographical levels is limited, if not absent. This is the first meta-analysis to investigate the point prevalence of EcO157 in cattle at the global level and to explore the factors contributing to variation in prevalence estimates. Seven electronic databases- CAB Abstracts, PubMed, Biosis Citation Index, Medline, Web of Knowledge, Scirus and Scopus were searched for relevant publications from 1980 to 2012. A random effect meta-analysis model was used to produce the pooled estimates. The potential sources of between study heterogeneity were identified using meta-regression. A total of 140 studies consisting 220,427 cattle were included in the meta-analysis. The prevalence estimate of EcO157 in cattle at the global level was 5.68% (95% CI, 5.16-6.20). The random effects pooled prevalence estimates in Africa, Northern America, Oceania, Europe, Asia and Latin America-Caribbean were 31.20% (95% CI, 12.35-50.04), 7.35% (95% CI, 6.44-8.26), 6.85% (95% CI, 2.41-11.29), 5.15% (95% CI, 4.21-6.09), 4.69% (95% CI, 3.05-6.33) and 1.65% (95% CI, 0.77-2.53), respectively. Between studies heterogeneity was evidenced in most regions. World region (p<0.001), type of cattle (p<0.001) and to some extent, specimens (p = 0.074) as well as method of pre-enrichment (p = 0.110), were identified as factors for variation in the prevalence estimates of EcO157 in cattle. The prevalence of the organism seems to be higher in the African and Northern American regions. The important factors that might have influence in the estimates of EcO157 are type of cattle and kind of screening specimen. Their roles need to be determined and they should be properly handled in any survey to estimate the true prevalence of EcO157.

  6. Characterization of limestone of region South and Southeast of Para; Caracterizacao de calcario da regiao Sul e Sudeste do Para

    Energy Technology Data Exchange (ETDEWEB)

    Marinho, A.R.O.; Vieira, J.H.A.; Antunes Junior, L.V.; Medeiros, A.C.; Souza, G.P., E-mail: marabaonline@gmail.com [Universidade Federal do Sul e Sudeste do Para (FEMAT/UNIFESSPA), Maraba, PA (Brazil)

    2014-07-01

    Limestone is used in daily activities, and it is common the use of products containing calcium carbonate in various applications, from construction to food production, air purification to sewage treatment, the sugar refining materials for the toothpaste, the manufacture of glass and steel in the manufacture of paper, plastics, paints, ceramics and many others. The Limestone present in the region of south and southeast of Para is presented in deposits that have not been explored on a large scale, being justified a deepening in characteristics thereof. For the characterization of the material, gross samples were comminuted by crushing and ball mill, sieved and then separated into aliquots. In the end were used fluorescence analysis of X-ray, diffraction X-rays, determination of the moisture and loss on ignition of the material at 950 °C for one hour, obtaining results of a dolomitic limestone. (author)

  7. Perceptions on hospitality when visiting secluded communities of guaranis, caiçaras e quilombolas in Paraty region

    Directory of Open Access Journals (Sweden)

    Luis Alberto Beares

    2008-10-01

    Full Text Available Tourism in secluded communities puts different cultures in contact with each other and must be handled carefully not to cause environmental damage as well as cultural loss which might jeopardize the local development and create hostile relationships. The proposal of in sito tourism, considering the local memory and patrimony as a hospitality potential, was observed during technical visitations to three communities located in the Paraty region and surroundings: Guarani, Caiçara (fishermen and Quilombola(African slaves descendants. Through field work involving visitations to communities and interviews with locals, information regarding cultural differences and the importance of the land occupation in the history of each of the communities was assessed. The common link in the history of these peoples is the struggle for the right of land possession. During visits when people shared their territory various forms of hospitality in each community were verified, issued from different cultures and cultural values.

  8. Squilibri regionali e dualismo finanziario in Italia: alcune riflessioni (Regional imbalances and financial dualism in Italy: some reflections

    Directory of Open Access Journals (Sweden)

    P. ALESSANDRINI

    2013-10-01

    Full Text Available The article provides brief reflections on the real and financial division of labor at the local level, with particular reference to Italy’s dualistic situation. The starting point is the finding of a large and persistent territorial divarication, across large subnational areas, between savings and investment. Important implications are drawn for the Italian financial structure, which has a decisive role in the processes of finance and adjustment of real imbalances not only among operators in surplus and deficit - something commonly taken into account - but also between regions. In this context, it is certainly relevant to ask whether the dualism in levels of development between the South and the rest of the country coexists and interacts with a corresponding financial dualism. Furthermore, how does the territorial distribution of productive activities and of the financial structure evolve? The author addresses these central questions. JEL Codes: O16, O52 

  9. Relación entre educación e ingresos en las regiones geográficas de Argentina

    OpenAIRE

    Gabriela Liliana GALASSI; Marcos Javier ANDRADA

    2011-01-01

    Como propone la teoría del capital humano, la educación es uno de los principales determinantes de los ingresos de los individuos. Además, es importante controlar las características socioeconómicas y demográfi cas, porque la calidad de vida y los hábitos afectan el modo de inserción en el mercado laboral y, en consecuencia, los ingresos. En este trabajo se indaga la relación empírica entre el ingreso y la educación recibida, para los trabajadores de las seis regiones de Argentina para el año...

  10. Storm/Quiet Ratio Comparisons Between TIMED/SABER NO (sup +)(v) Volume Emission Rates and Incoherent Scatter Radar Electron Densities at E-Region Altitudes

    Science.gov (United States)

    Fernandez, J. R.; Mertens, C. J.; Bilitza, D.; Xu, X.; Russell, J. M., III; Mlynczak, M. G.

    2009-01-01

    Broadband infrared limb emission at 4.3 microns is measured by the TIMED/SABER instrument. At night, these emission observations at E-region altitudes are used to derive the so called NO+(v) Volume Emission Rate (VER). NO+(v) VER can be derived by removing the background CO2(v3) 4.3 microns radiance contribution using SABER-based non-LTE radiation transfer models, and by performing a standard Abel inversion on the residual radiance. SABER observations show that NO+(v) VER is significantly enhanced during magnetic storms in accordance with increased ionization of the neutral atmosphere by auroral electron precipitation, followed by vibrational excitation of NO+ (i.e., NO+(v)) from fast exothermic ion-neutral reactions, and prompt infrared emission at 4.3 m. Due to charge neutrality, the NO+(v) VER enhancements are highly correlated with electron density enhancements, as observed for example by Incoherent Scatter Radar (ISR). In order to characterize the response of the storm-time E-region from both SABER and ISR measurements, a Storm/Quiet ratio (SQR) quantity is defined as a function of altitude. For SABER, the SQR is the ratio of the storm-to-quiet NO+(v) VER. SQR is the storm-to-quiet ratio of electron densities for ISR. In this work, we compare SABER and ISR SQR values between 100 to 120 km. Results indicate good agreement between these measurements. SQR values are intended to be used as a correction factor to be included in an empirical storm-time correction to the International Reference Ionosphere model at E-region altitudes.

  11. Economic globalisation. Regional integration and protection of foreign investments in Brazil Globalização econômica. Integração regional e proteção de inversões estrangeiras no Brasil

    Directory of Open Access Journals (Sweden)

    Luis Maria Chamorro Coronado

    2009-12-01

    Full Text Available Economic globalization poses a challenge to enterprises looking for new markets. These enterprises search for new markets in countries that belong to regional integration organizations whose regulations- as well as those of the internal system of each country - shape the legal framework for foreign investments. Foreign enterprises investing in Brazil, for instance, are affected by Brazilian law as well as by Mercosur regulations. This article focuses on the Multilateral Investment Guarantee Agency and its insurance schemes - an institution that protects foreign investment in Brazil - as well as on a description of the Multilateral Conventions which rule the treatment and protection of foreign investments. This article concludes with a review of Mercosur´s main legal documents to protect investments and their interaction with Bilateral Investment Treaties, containing the new international law on foreign investments. To this day, Brazil has signed some bilateral investment treaties but has not yet ratified them.A globalização econômica tem posto um desafio às empresas que buscam novos mercados. Introduzem-se em países que pertencem a Organizações de integração regional, cujas normas, além das internas de cada país, configuram o marco jurídico de suas intervenções. As empresas estrangeiras que investem no Brasil ficam, portanto, afetadas pelo Direito brasileiro e à sua pertinência ao MERCOSUL. Como passo prévio ao estudo do sistema mais adequado à proteção dos investimentos no Brasil, e do Organismo Multilateral de garantia de Investimento, e seus esquemas de asseguramento, o presente trabalho contém a descrição dos Convênios multilaterais que regulam o tratamento e proteção dos investimentos exteriores. O artigo conclui com o estudo dos intrumentos legais para a proteção dos investimentos no MERCOSUL e sua interação com os Acordos de Promoção e Proteção Recíproca de Investimento (APPRIs, que contêm o novo

  12. Sporadic potassium layers and their connection to sporadic E layers in the mesopause region at Beijing, China

    Directory of Open Access Journals (Sweden)

    Jing Jiao

    2017-06-01

    Full Text Available A double-laser beam lidar to measure potassium (K layer at Beijing (40.5° N, 116.2° E was successfully developed in 2010. The parameters of sporadic Ks layers and their distributions were given. The seasonal distribution of Ks occurrence frequency was obtained, with two maxima in July and January. The seasonal distributions of sporadic Es layer occurrence frequency over Beijing differ from those of Ks. However, the good correlation between Es and Ks in the case-by-case studies supports the mechanism of neutralization of metal ions in a descending Es layer.

  13. A influência da proximidade tecnológica e geográfica sobre a inovação regional no Brasil The influence of the technological proximity and the geographical proximity on Brazilian regional innovation

    Directory of Open Access Journals (Sweden)

    Eduardo Gonçalves

    2011-04-01

    Full Text Available O objetivo deste trabalho é verificar a influência da proximidade geográfica e da proximidade tecnológica sobre a inovação regional no Brasil, medida por depósitos de patentes no período 1999-2001 para mesorregiões geográficas. Para tanto, utilizaram-se técnicas de Análise Exploratória de Dados Espaciais (AEDE e de econometria espacial. Os dados de patentes foram organizados em quatro clusters tecnológicos segundo critérios de proximidade cognitiva, como biofarmacêutico, desenvolvimento de novos materiais, bens mecânicos e de consumo e tecnologias eletroeletrônicas, revelando um padrão de concentração da atividade tecnológica em poucas mesorregiões brasileiras. Além disso, foi calculada a medida de proximidade tecnológica de Jaffe para ponderar a vizinhança geográfica pelo grau de similaridade tecnológica das mesorregiões. Os resultados confirmam a hipótese de transbordamentos de conhecimento mediados tecnológica e geograficamente.The aim of this paper is to determine the influence of technological proximity and geographical proximity on Brazilian regional innovation, measured by patent applications over the period 1999-2001 for Brazilian geographical mesoregions. First, the paper undertakes an Exploratory Spatial Data Analysis (ESDA and then uses spatial econometric techniques. According with procedures based on cognitive proximity the patent data are organized into four technological clusters such as chemical and bio-pharmaceutical, new materials, mechanical and process technologies and electrical and electronic technologies. The four aforementioned clusters exhibit a concentrated regional pattern of technological activity over few Brazilian mesoregions. Moreover, the paper uses a Jaffe's measure of technological distance in order to construct a matrix in which the technological similarity is weighted by the geographical proximity. The results corroborate the hypothesis of geographically and technologically

  14. Epidemiology of Extended-Spectrum β-Lactamase-Producing E. coli and Vancomycin-Resistant Enterococci in the Northern Dutch-German Cross-Border Region.

    Science.gov (United States)

    Zhou, Xuewei; García-Cobos, Silvia; Ruijs, Gijs J H M; Kampinga, Greetje A; Arends, Jan P; Borst, Dirk M; Möller, Lieke V; Holman, Nicole D; Schuurs, Theo A; Bruijnesteijn van Coppenraet, Lesla E; Weel, Jan F; van Zeijl, Jan H; Köck, Robin; Rossen, John W A; Friedrich, Alexander W

    2017-01-01

    Objectives: To reveal the prevalence and epidemiology of extended-spectrum β-lactamase (ESBL)- and/or plasmid AmpC (pAmpC)- and carbapenemase (CP) producing Enterobacteriaceae and vancomycin-resistant enterococci (VRE) across the Northern Dutch-German border region. Methods: A point-prevalence study on ESBL/pAmpC/CP producing Enterobacteriaceae and VRE was carried out in hospitalized patients in the Northern Netherlands ( n = 445, 2012-2013) and Germany ( n = 242, 2012). Healthy individuals from the Dutch community ( n = 400, 2010-2012) were also screened. In addition, a genome-wide gene-by-gene approach was applied to study the epidemiology of ESBL- Escherichia coli and VRE. Results: A total of 34 isolates from 27 patients (6.1%) admitted to Dutch hospitals were ESBL/pAmpC positive and 29 ESBL- E. coli , three pAmpC- E. coli , one ESBL- Enterobacter cloacae , and one pAmpC- Proteus mirabilis were found. In the German hospital, 18 isolates (16 E. coli and 2 Klebsiella pneumoniae ) from 17 patients (7.7%) were ESBL positive. In isolates from the hospitalized patients CTX-M-15 was the most frequently detected ESBL-gene. In the Dutch community, 11 individuals (2.75%) were ESBL/pAmpC positive: 10 ESBL - E. coli (CTX-M-1 being the most prevalent gene) and one pAmpC E. coli . Six Dutch (1.3%) and four German (3.9%) hospitalized patients were colonized with VRE. Genetic relatedness by core genome multi-locus sequence typing (cgMLST) was found between two ESBL- E. coli isolates from Dutch and German cross-border hospitals and between VRE isolates from different hospitals within the same region. Conclusion: The prevalence of ESBL/pAmpC- Enterobacteriaceae was similar in hospitalized patients across the Dutch-German border region, whereas VRE prevalence was slightly higher on the German side. The overall prevalence of the studied pathogens was lower in the community than in hospitals in the Northern Netherlands. Cross-border transmission of ESBL- E. coli and VRE seems

  15. Epidemiology of Extended-Spectrum β-Lactamase-Producing E. coli and Vancomycin-Resistant Enterococci in the Northern Dutch–German Cross-Border Region

    Directory of Open Access Journals (Sweden)

    Xuewei Zhou

    2017-10-01

    Full Text Available Objectives: To reveal the prevalence and epidemiology of extended-spectrum β-lactamase (ESBL- and/or plasmid AmpC (pAmpC- and carbapenemase (CP producing Enterobacteriaceae and vancomycin-resistant enterococci (VRE across the Northern Dutch–German border region.Methods: A point-prevalence study on ESBL/pAmpC/CP producing Enterobacteriaceae and VRE was carried out in hospitalized patients in the Northern Netherlands (n = 445, 2012–2013 and Germany (n = 242, 2012. Healthy individuals from the Dutch community (n = 400, 2010–2012 were also screened. In addition, a genome-wide gene-by-gene approach was applied to study the epidemiology of ESBL-Escherichia coli and VRE.Results: A total of 34 isolates from 27 patients (6.1% admitted to Dutch hospitals were ESBL/pAmpC positive and 29 ESBL-E. coli, three pAmpC-E. coli, one ESBL-Enterobacter cloacae, and one pAmpC-Proteus mirabilis were found. In the German hospital, 18 isolates (16 E. coli and 2 Klebsiella pneumoniae from 17 patients (7.7% were ESBL positive. In isolates from the hospitalized patients CTX-M-15 was the most frequently detected ESBL-gene. In the Dutch community, 11 individuals (2.75% were ESBL/pAmpC positive: 10 ESBL-E. coli (CTX-M-1 being the most prevalent gene and one pAmpC E. coli. Six Dutch (1.3% and four German (3.9% hospitalized patients were colonized with VRE. Genetic relatedness by core genome multi-locus sequence typing (cgMLST was found between two ESBL-E. coli isolates from Dutch and German cross-border hospitals and between VRE isolates from different hospitals within the same region.Conclusion: The prevalence of ESBL/pAmpC-Enterobacteriaceae was similar in hospitalized patients across the Dutch–German border region, whereas VRE prevalence was slightly higher on the German side. The overall prevalence of the studied pathogens was lower in the community than in hospitals in the Northern Netherlands. Cross-border transmission of ESBL-E. coli and VRE seems unlikely

  16. Development of Three PCR Assays for the Differentiation between Echinococcus shiquicus, E. granulosus (G1 genotype), and E. multilocularis DNA in the Co-Endemic Region of Qinghai-Tibet plateau, China

    Science.gov (United States)

    Boufana, Belgees; Umhang, Gérald; Qiu, Jiamin; Chen, Xingwang; Lahmar, Samia; Boué, Franck; Jenkins, David; Craig, Philip

    2013-01-01

    To investigate echinococcosis in co-endemic regions, three polymerase chain reaction (PCR) assays based on the amplification of a fragment within the NADH dehydrogenase subunit 1 (ND1) mitochondrial gene were optimized for the detection of Echinococcus shiquicus, Echinococcus granulosus G1, and Echinococcus multilocularis DNA derived from parasite tissue or canid fecal samples. Specificity using parasite tissue-derived DNA was found to be 100% except for E. shiquicus primers that faintly detected E. equinus DNA. Sensitivity of the three assays for DNA detection was between 2 and 10 pg. Ethanol precipitation of negative PCR fecal samples was used to eliminate false negatives and served to increase sensitivity as exemplified by an increase in detection from 0% to 89% of E. shiquicus coproDNA using necropsy-positive fox samples. PMID:23438764

  17. Os diferentes papéis, propósitos e resultados dos modelos nacionais e regionais de educação Different roles, purposes and outcomes of national and regional models of education

    Directory of Open Access Journals (Sweden)

    Roger Dale

    2009-10-01

    Full Text Available Este artigo discute a natureza e as posturas, atualmente variáveis, da educação por meio da distinção entre os papéis, propósitos e resultados de modelos educativos em níveis nacional e regional (supranacional, não subnacional. Propõe também o surgimento de um novo tipo de modelo regional de educação, que difere dos modelos nacionais em termos de conteúdo, papel e objetivo, e mantém com eles uma relação que não é de hierarquia, de convergência nem de escala. Comparam-se seus papéis no contrato social pela educação, tendo o Sistema Nacional de Educação como modelo-"padrão". Embora ambos sejam parte das contribuições da educação para os meios de produção e distribuição de bem-estar, desempenham papéis diferentes. Como exemplos, o artigo examina o processo Bolonha, na União Europeia (UE, e a natureza e as possíveis consequências do projeto que busca "exportá-lo" para a América Latina. Esses dois casos sugerem que os resultados-chave envolvem a "re-construção" tanto da região quanto, e mais particularmente, da educação superior como setor. O artigo conclui propondo que esses desenvolvimentos podem culminar em divisões funcionais, escalares e setoriais do trabalho educacional.This paper discusses the currently changing nature and roles of education through distinguishing between the roles, purposes and outcomes of educational models at national and regional (supra- rather than sub-national levels. It proposes the emergence of a new kind of regional model of education, that differs from national models in content, role and purpose, and where the relationship between the two models is neither hierarchical, converging or scaled-up. The two models are compared in terms of their role in the social contract for education, and the national education system is taken as the 'default' model. While both models are part of education's contribution to the means of production and distribution of well-being, they play

  18. Cineturismo e valorizzazione del territorio: il caso Puglia / Cine-tourism and territory enhancement: the case of Puglia region

    Directory of Open Access Journals (Sweden)

    Michele Vigilante

    2016-05-01

    Full Text Available Il cineturismo rappresenta un fenomeno socio-culturale recente e in forte diffusione in Italia. Il suo legame con la valorizzazione del territorio è inscindibile dal momento in cui lo spettatore sceglie un determinato luogo da visitare, stimolato dalla visione di un film, di una fiction o di un cortometraggio. La valorizzazione del territorio attraverso il cinema non è automatica. Vi sono luoghi che grazie a dei film di successo hanno riscontrato un afflusso esponenziale di turisti e altri luoghi dove questo non è avvenuto. Predisporre spazi per l'accoglienza di produzioni cinematografiche o finanziare le produzioni cinematografiche in uno specifico territorio consente un maggiore interesse, da parte dei registi, nei confronti di quelle location che di quel territorio fanno parte.  The film tourism is a socio-cultural phenomenon recently and rapidly spread in Italy. His connection with the development of the area is inseparable from the moment when the viewer chooses a certain place to visit, stimulated by watching a movie, a drama or a short film. The development of the area through cinema is not automatic. There are places that thanks to the hit movie found an exponential influx of tourists and other places where this has not happened. Provide space for the reception of film productions or finance film productions in a specific area allows a greater interest on the part of directors, in respect of those locations that are part of that territory.

  19. Determinantes espaciais e socioeconômicos do suicídio no Brasil: uma abordagem regional

    Directory of Open Access Journals (Sweden)

    Ludmilla R. C. Gonçalves

    2012-01-01

    Full Text Available A Organização Mundial da Saúde avalia o suicídio como um problema de saúde pública, estando entre as dez causas mais frequentes de morte, além de ser a segunda ou terceira causa de morte entre 15 e 34 anos de idade. Estimativas mostram que para cada suicídio, existem pelo menos dez tentativas suficientemente sérias que exigem atenção médica e para cada tentativa de suicídio registrada, existem quatro não conhecidas. O objetivo desse artigo é avaliar os determinantes socioeconômicos das taxas de suicídio por microrregiões brasileiras, levando em consideração aspectos espaciais do problema. A hipótese desse artigo é que existe um “efeito contágio” espacial para o suicídio, ou seja, as taxas de suicídio dos vizinhos de uma microrregião são importantes determinantes do comportamento dessa variável em outra microrregião. Para tal, são usadas técnicas de econometria espacial que permitem avaliar se existe dependência espacial entre as taxas de suicídio das microrregiões.

  20. n+235U resonance parameters and neutron multiplicities in the energy region below 100 eV

    Directory of Open Access Journals (Sweden)

    Pigni Marco T.

    2017-01-01

    Full Text Available In August 2016, following the recent effort within the Collaborative International Evaluated Library Organization (CIELO pilot project to improve the neutron cross sections of 235U, Oak Ridge National Laboratory (ORNL collaborated with the International Atomic Energy Agency (IAEA to release a resonance parameter evaluation. This evaluation restores the performance of the evaluated cross sections for the thermal- and above-thermal-solution benchmarks on the basis of newly evaluated thermal neutron constants (TNCs and thermal prompt fission neutron spectra (PFNS. Performed with support from the US Nuclear Criticality Safety Program (NCSP in an effort to provide the highest fidelity general purpose nuclear database for nuclear criticality applications, the resonance parameter evaluation was submitted as an ENDF-compatible file to be part of the next release of the ENDF/B-VIII.0 nuclear data library. The resonance parameter evaluation methodology used the Reich-Moore approximation of the R-matrix formalism implemented in the code SAMMY to fit the available time-of-flight (TOF measured data for the thermal induced cross section of n+235U up to 100 eV. While maintaining reasonably good agreement with the experimental data, the validation analysis focused on restoring the benchmark performance for 235U solutions by combining changes to the resonance parameters and to the prompt resonance v̅ below 100 eV.

  1. AVALIAÇÃO DOS BENEFÍCIOS SECUNDÁRIOS DE PROJETOS MDL: CONTRIBUIÇÃO AO CONTROLE DE POLUIÇÃO E AO DESENVOLVIMENTO LOCAL E REGIONAL

    Directory of Open Access Journals (Sweden)

    Pedro Camargo Amaral

    2011-05-01

    Full Text Available Considerando o aumento da importância de poluentes locais, regionais e globais nas atividades humanas, notados os acordos internacionais para controlar e reduzir as emissões de gases de efeito estufa destaca-se o Mecanismo de Desenvolvimento Limpo do Protocolo de Kyoto, como ferramenta para promover a redução de emissões de GEE e contribuir para o controle de poluição e desenvolvimento local e regional. Dentro do processo de aprovação de projetos de MDL no Brasil, existe a necessidade de se atender aos critérios relacionados à sustentabilidade local, definidos pelo governo brasileiro no documento denominado Anexo III. O presente estudo busca avaliar o processo que culminou com a definição dos critérios de sustentabilidade para projetos de MDL no Brasil e avaliar o impacto local e regional de projetos aprovados pelo governo brasileiro, no que concerne os poluentes ambientais CO, NOx, SOx, MP e hidrocarbonetos, assim como impactos diretos à fauna, flora e recursos hídricos. Para a avaliação dos projetos foi proposta uma metodologia, baseada em metodologias previamente sugeridas para avaliação de projetos de MDL. Concluí-se que os critérios estabelecidos para o Anexo III contemplam, em essência, os critérios sugeridos nos trabalhos que antecederam sua definição. Por outro lado, é notável a diminuição do peso de benefícios secundários no mecanismo, como critérios obrigatórios ou classificatórios, quando se comparam as idéias originais àquelas que de fato foram implementadas. Ao mesmo tempo, devem ser valorizados os impactos secundários positivos advindos dos projetos de MDL, notados àqueles apresentados neste trabalho. Ressalta-se que os impactos ambientais positivos são extremamente relacionados ao menor consumo de combustíveis fósseis (não desconsiderando também a menor necessidade de produção dos mesmos e aos impactos associados a estes combustíveis.

  2. Internet use, eHealth literacy and attitudes toward computer/internet among people with schizophrenia spectrum disorders: a cross-sectional study in two distant European regions.

    Science.gov (United States)

    Athanasopoulou, Christina; Välimäki, Maritta; Koutra, Katerina; Löttyniemi, Eliisa; Bertsias, Antonios; Basta, Maria; Vgontzas, Alexandros N; Lionis, Christos

    2017-09-20

    Individuals with schizophrenia spectrum disorders use the Internet for general and health-related purposes. Their ability to find, understand, and apply the health information they acquire online in order to make appropriate health decisions - known as eHealth literacy - has never been investigated. The European agenda strives to limit health inequalities and enhance mental health literacy. Nevertheless, each European member state varies in levels of Internet use and online health information-seeking. This study aimed to examine computer/Internet use for general and health-related purposes, eHealth literacy, and attitudes toward computer/Internet among adults with schizophrenia spectrum disorders from two distant European regions. Data were collected from mental health services of psychiatric clinics in Finland (FI) and Greece (GR). A total of 229 patients (FI = 128, GR = 101) participated in the questionnaire survey. The data analysis included evaluation of frequencies and group comparisons with multiple linear and logistic regression models. The majority of Finnish participants were current Internet users (FI = 111, 87%, vs. GR = 33, 33%, P eHealth literacy of Internet users (previous and current Internet users) was found significantly higher in the Finnish group (FI: Mean = 27.05, SD 5.36; GR: Mean = 23.15, SD = 7.23, P eHealth literacy and Interest. The Finnish group of Internet users scored higher in eHealth literacy, while the Greek group of never Internet users had a higher Interest in computer/Internet. eHealth literacy is either moderate (Finnish group) or low (Greek group). Thus, exposure to ICT and eHealth skills training are needed for this population. Recommendations to improve the eHealth literacy and access to health information among these individuals are provided.

  3. Integração regional e coesão social no Mercosul: uma análise à luz da teoria da dependência

    Directory of Open Access Journals (Sweden)

    Jonatan Pozzobon Müller

    2011-06-01

    Full Text Available A história da América Latina ocorreu de forma paralela ao sistema capitalista internacional. O continente inaugurou, já no século XV, uma relação histórica de dependência com o centro do sistema mundial, fato que condicionou o modelo de desenvolvimento econômico e social ao fracasso. Com a colaboração nefasta da globalização neoliberal das últimas décadas, a região mergulhou em um caos social generalizado. A fim de reverter essa situação, instigaram-se os debates acerca dos processos de integração regional e de como eles poderiam viabilizar uma inserção autônoma na disputa capitalista internacional. Conforme o concebido pelos intelectuais da teoria da dependência da década de 1960, a ação integrada dos agentes sociais, parlamentares, partidários e sindicais alavancaria o pleno desenvolvimento regional. O objetivo deste artigo é situar a integração regional como pré-requisito para se alcançar a coesão social no âmbito do Mercosul, garantindo, dessa forma, uma inserção adequada dos Estados-membros no sistema mundial. Assim, primeiramente, será explanado o processo histórico da América Latina. Na sequência, será abordada a integração regional, segundo a teoria da dependência de Ruy Mauro Marini, como mecanismo capaz de assegurar o bem-estar social e a inserção autônoma no sistema internacional. Por fim, abre-se espaço para as reflexões sobre a coesão social no âmbito do Mercosul. Utilizando-se, portanto, do método dedutivo de pesquisa, o presente texto encaminhar-se-á dentro do rol de discussões acadêmicas vinculadas ao estudo do aprofundamento do modelo de integração e coesão social no Mercosul.

  4. Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix

    DEFF Research Database (Denmark)

    Heim, Joel B; Squirewell, Edwin J; Neu, Ancilla

    2017-01-01

    Focal adhesion kinase (FAK) is a nonreceptor tyrosine kinase involved in development and human disease, including cancer. It is currently thought that the four-point one, ezrin, radixin, moesin (FERM)-kinase domain linker, which contains autophosphorylation site tyrosine (Y) 397, is not required...... for in vivo FAK function until late midgestation. Here, we directly tested this hypothesis by generating mice with FAK Y397-to-phenylalanine (F) mutations in the germline. We found that Y397F embryos exhibited reduced mesodermal fibronectin (FN) and osteopontin expression and died during mesoderm development...... and other FN-type matrix in both mouse embryonic fibroblasts and human melanoma. Our data support a model in which FAK Y397 autophosphorylation is required for FAK function in vivo and is positively regulated by MYO1E....

  5. Magnetic rotation spectra of Co/Pt and Co/Cu multilayers in 50-90 eV region

    International Nuclear Information System (INIS)

    Saito, K.; Igeta, M.; Ejima, T.; Hatano, T.; Arai, A.; Watanabe, M.

    2005-01-01

    Faraday rotation spectra of Co/Pt multilayers were obtained in the region including Co M 2,3 and Pt N 6,7 absorption edges by using multilayer polarizers, and were transformed to magnetic circular dichroism (MCD) spectra by Kramers-Kronig analysis (KKA). From the dependence of the rotation angle on the layer thickness, it was suggested that the magnetization of Co tends to be uniform in Co layers and that of Pt is localized at Co/Pt interfaces. The orbital magnetic moment of Co was estimated to be about 0.17 μ B /Co. The similarity of electronic states around magnetized Pt site between Co/Pt multilayers and CoPt 3 alloy is suggested by the resemblance of the MCD spectra of both materials around Pt N 6,7 edges. In addition, magnetic Kerr rotation of Co/Cu multilayer was measured and was observed around Co M 2,3 and Cu M 2,3 absorption edges

  6. Ground-based measurements of the vertical E-field in mountainous regions and the "Austausch" effect

    Science.gov (United States)

    Yaniv, Roy; Yair, Yoav; Price, Colin; Mkrtchyan, Hripsime; Lynn, Barry; Reymers, Artur

    2017-06-01

    Past measurements of the atmospheric vertical electric field (Ez or potential gradient) at numerous land stations showed a strong response of the daily electric field to a morning local effect known as ;Austausch; - the transport of electrical charges due to increased turbulence. In mountainous regions, nocturnal charge accumulation, followed by an attachment process to aerosols near the surface in valleys, known as the electrode effect, is lifted as a charged aerosol layer by anabatic (upslope) winds during the morning hours due to solar heating. Ground-based measurements during fair weather days were conducted at three mountain stations in Israel and Armenia. We present results of the mean diurnal variation of Ez and make comparisons with the well-known Carnegie curve and with past measurements of Ez on mountains. We report a good agreement between the mean diurnal curves of Ez at various mountain stations and the time of local sunrise when the Ez is found to increase. We attribute this morning maximum to the Austausch (or exchange) layer effect. We support our findings with conduction and turbulent current measurements showing high values of ions and charged aerosols being transported by winds from morning to noon local time, and by model simulations showing the convergence of winds in the early morning hours toward the mountain peak.

  7. A arquitetura e o planejamento urbano-regional emface do processo de mundialização

    Directory of Open Access Journals (Sweden)

    Alessandro Ventura

    2003-01-01

    Full Text Available 1. Main characteristics of the current process ofglobalization; instability created by the formation ofthe global society; changes in the relations of space-time in architecture and urbanism; 2. The physical planning in the face of changes;contributions of four Chartes – Atenas, LaTourrette, Andes and UIA / Beijing-, of geographersand economists for the field of regional planning andarchitecture; the current changes and theirconsequences in the process of physical planning; 3. The modular production in the globalization; timeof construction of buildings in view of thetransformations; the immobility submits thebuilding to its urban context; the mobility in theconstruction process of buildings is fundamental fornew configurations of the city; 4. The environmental factors in the process of lobalization and the introduction of safeguards ofterritorial character; the scattering of activities and theconsequent conversion of the local in a commonplace;the global architecture and its foreign elementsdisrespect cultural and environmental values; 5. Preservation of human dimension and theincreased value of the local must give an outstandingplace to the social sector and guarantee the ways forthe development of architecture and planning.

  8. Relación entre educación e ingresos en las regiones geográficas de Argentina

    Directory of Open Access Journals (Sweden)

    Gabriela Liliana GALASSI

    2011-01-01

    Full Text Available Como propone la teoría del capital humano, la educación es uno de los principales determinantes de los ingresos de los individuos. Además, es importante controlar las características socioeconómicas y demográfi cas, porque la calidad de vida y los hábitos afectan el modo de inserción en el mercado laboral y, en consecuencia, los ingresos. En este trabajo se indaga la relación empírica entre el ingreso y la educación recibida, para los trabajadores de las seis regiones de Argentina para el año 2010, empleando los datos de la Encuesta Permanente de Hogares. Se emplea la conocida especifi cación de la Ecuación de Mincer, incorporando dos refi namientos: la corrección de Heckman por sesgo de selección, y la introducción de una serie de variables socioeconómicas y demográfi cas mutuamente correlacionadas en el modelo.

  9. INDICAÇÕES GEOGRÁFICAS (IGS COMO FERRAMENTA PARA DESENVOLVIMENTO REGIONAL: UMA PROSPECÇÃO TECNOLÓGICA SOBRE IGS RELACIONADAS À FARINHA E MANDIOCA

    Directory of Open Access Journals (Sweden)

    Nina Paloma Neves Calmon de Siqueira Branco

    2014-07-01

    Full Text Available As Indicações Geográficas são qualificações para produtos e serviços atribuídas por características genuínas que os vinculam à sua região produtora de origem. No mercado global, que intensificou as relações culturais, turísticas e econômicas entre os diversos continentes do mundo, as IG vêm emergindo como ferramenta de desenvolvimento em nível local, regional, nacional e internacional. No Nordeste brasileiro, a Rede dos Núcleos de Inovação Tecnológica (Rede NIT-NE, presentes  em instituições de pesquisa, desenvolveu atividades de disseminação de Propriedade Intelectual, dentre as quais as IG. Nesse cenário, foi estabelecido o Edital de Apoio à Caracterização de Indicações Geográficas na Bahia, pela Fundação de Amparo a Pesquisa do Estado da Bahia­ (FAPESB. Este artigo trata da prospecção tecnológica em IG para farinhas e mandioca, no mundo, e da implantação de um dos projetos aprovados nesse Edital: o potencial de IG para a farinha de mandioca de Copioba, do Recôncavo Baiano.

  10. Using eHealth to engage and retain priority populations in the HIV treatment and care cascade in the Asia-Pacific region: a systematic review of literature.

    Science.gov (United States)

    Purnomo, Julianita; Coote, Katherine; Mao, Limin; Fan, Ling; Gold, Julian; Ahmad, Raghib; Zhang, Lei

    2018-02-17

    The exponential growth in the reach and development of new technologies over the past decade means that mobile technologies and social media play an increasingly important role in service delivery models to maximise HIV testing and access to treatment and care. This systematic review examines the impact of electronic and mobile technologies in medical care (eHealth) in the linkage to and retention of priority populations in the HIV treatment and care cascade, focussing on the Asia-Pacific region. The review was informed by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement from the Cochrane Collaboration guidelines. Both grey and published scientific literature from five different databases were searched for all original articles in English published from 2010 to 2017. Studies conducted outside the Asia-Pacific region or not including HIV priority populations were excluded. The methodological quality of studies included in the review was assessed using the Quality Assessment Tool for Quantitative Studies. The database search identified 7309 records. Of the 224 peer-reviewed articles identified for full text review, 16 studies from seven countries met inclusion criteria. Six cross sectional studies found evidence to support the use of eHealth, via text messages, instant messaging, social media and health promotion websites, to increase rates of HIV testing and re-testing among men who have sex with men (MSM). Evidence regarding the efficacy of eHealth interventions to improve antiretroviral treatment (ART) adherence was mixed, where one randomised controlled trial (RCT) showed significant benefit of weekly phone call reminders on improving ART adherence. Three further RCTs found that biofeedback eHealth interventions that provided estimated ART plasma concentration levels, showed promising results for ART adherence. This review found encouraging evidence about how eHealth can be used across the HIV treatment and care cascade in

  11. Prevalence of immunoglobulin E-mediated food allergy in 6-9-year-old urban schoolchildren in the eastern Black Sea region of Turkey.

    Science.gov (United States)

    Orhan, F; Karakas, T; Cakir, M; Aksoy, A; Baki, A; Gedik, Y

    2009-07-01

    The prevalence of adverse reactions to food in childhood in Turkey is not known. We aimed to investigate the prevalence and characteristics of IgE-mediated food allergies (FAs) in 6-9-year-old urban schoolchildren. This cross-sectional study recruited 3500 of the randomly selected 6-9-year-old urban schoolchildren from the eastern Black Sea region of Turkey during 2006. Following a self-administered questionnaire completed by the parents and the child, consenting children were invited for skin prick tests (SPTs) and oral food challenges. Children with suspected IgE-mediated FA were skin prick tested with a predefined panel of food allergens (milk, hen's egg, soy, wheat, peanut, fish, and hazelnut), aeroallergens (Dermatophagoides pteronyssinus, Dermatophagoides farinae, cat, dog, Alternaria, grass pollen mix, weed pollen mix, and tree pollen mix), and food allergens reported in the questionnaire. All children with a positive SPT to any food were invited for a double-blind, placebo-controlled food challenge (DBPCFC). The prevalence of IgE-mediated FA was established using DBPCFCs. The response rate to the questionnaire was 78.2% (2739/3500). The estimated prevalence of parental-reported IgE-mediated FA was 5.7% (156/2739) [95% confidence interval (CI), 4.83-6.57%]. The rate of sensitization to the food allergens was 33.1% (48/145) in the parental-reported group. The confirmed prevalence of IgE-mediated FA by means of DBPCFC in 6-9-year-old urban schoolchildren living in the eastern Black Sea region of Turkey was 0.80% (22/2739) (95% CI, 0.47-1.13%). The most common allergenic foods were beef (31.8%), cow's milk (18.1%), cocoa (18.1%), hen's egg (13.6%), and kiwi (13.6%). The rate of reported IgE-mediated FA was significantly higher than clinically confirmed FA by means of DBPCFC (odds ratio, 7.46; 95% CI, 4.67-12.01; Pfoods was different and somewhat unique to the eastern Black Sea region of Turkey when compared with western countries.

  12. A computational approach identifies two regions of Hepatitis C Virus E1 protein as interacting domains involved in viral fusion process

    Directory of Open Access Journals (Sweden)

    El Sawaf Gamal

    2009-07-01

    Full Text Available Abstract Background The E1 protein of Hepatitis C Virus (HCV can be dissected into two distinct hydrophobic regions: a central domain containing an hypothetical fusion peptide (FP, and a C-terminal domain (CT comprising two segments, a pre-anchor and a trans-membrane (TM region. In the currently accepted model of the viral fusion process, the FP and the TM regions are considered to be closely juxtaposed in the post-fusion structure and their physical interaction cannot be excluded. In the present study, we took advantage of the natural sequence variability present among HCV strains to test, by purely sequence-based computational tools, the hypothesis that in this virus the fusion process involves the physical interaction of the FP and CT regions of E1. Results Two computational approaches were applied. The first one is based on the co-evolution paradigm of interacting peptides and consequently on the correlation between the distance matrices generated by the sequence alignment method applied to FP and CT primary structures, respectively. In spite of the relatively low random genetic drift between genotypes, co-evolution analysis of sequences from five HCV genotypes revealed a greater correlation between the FP and CT domains than respect to a control HCV sequence from Core protein, so giving a clear, albeit still inconclusive, support to the physical interaction hypothesis. The second approach relies upon a non-linear signal analysis method widely used in protein science called Recurrence Quantification Analysis (RQA. This method allows for a direct comparison of domains for the presence of common hydrophobicity patterns, on which the physical interaction is based upon. RQA greatly strengthened the reliability of the hypothesis by the scoring of a lot of cross-recurrences between FP and CT peptides hydrophobicity patterning largely outnumbering chance expectations and pointing to putative interaction sites. Intriguingly, mutations in the CT

  13. Assessing CO2 emissions of electric vehicles for e-sharing and home care. Two cases developed at Valencian region

    Energy Technology Data Exchange (ETDEWEB)

    Iacono Ferreira, V.G. Lo; Torregrosa Lopez, J.I.; Colomer Ferrandiz, J.V.

    2016-07-01

    Assessing the environmental impact of transport has been an issue over the last decade. The general framework is established and the followings factors must be considered to obtain results as accurate as possible. Among others (a) the study should considered the entire life cycle if possible: building & materials, usage phase and waste treatment and (b) usage phase assessment must be developed under real conditions in addition to lab tests. When the object of study is urban private transport, some extra lines can be taken into account considering the high impact that environmental initiatives makes in society. The information that local authorities and community receives about the initiative is as relevant as the environmental benefits obtain of the implementation of the project. In this paper, we present the methodology developed to assess CO2 emissions of electric vehicles intendent to car-sharing and home care; two projects developed at Valencian region. We deepen in the relevance and type of information obtain and manage for both studies with a life cycle vision. As a result of usage phase assessment, field test proves to be revealing giving a more realistic vision of the benefits of the project. Theoretical assessments were useful to consider the implementation of a certain project and the necessary support complementing the entity of the study. Resources needed to develop field test might skew results by biasing the study. Attention need to be paid in order to manage resources to set up field tests and avoid setting up field tests due to available resources. Bibliographic studies have shown building, materials and waste treatment depends on available data. Life cycle assessment seems to be the most adequate tool to obtain accurate results although the cost of the assessment is high and might not show significant differences between cars of similar characteristics. (Author)

  14. Global MYCN transcription factor binding analysis in neuroblastoma reveals association with distinct E-box motifs and regions of DNA hypermethylation.

    LENUS (Irish Health Repository)

    Murphy, Derek M

    2009-01-01

    BACKGROUND: Neuroblastoma, a cancer derived from precursor cells of the sympathetic nervous system, is a major cause of childhood cancer related deaths. The single most important prognostic indicator of poor clinical outcome in this disease is genomic amplification of MYCN, a member of a family of oncogenic transcription factors. METHODOLOGY: We applied MYCN chromatin immunoprecipitation to microarrays (ChIP-chip) using MYCN amplified\\/non-amplified cell lines as well as a conditional knockdown cell line to determine the distribution of MYCN binding sites within all annotated promoter regions. CONCLUSION: Assessment of E-box usage within consistently positive MYCN binding sites revealed a predominance for the CATGTG motif (p<0.0016), with significant enrichment of additional motifs CATTTG, CATCTG, CAACTG in the MYCN amplified state. For cell lines over-expressing MYCN, gene ontology analysis revealed enrichment for the binding of MYCN at promoter regions of numerous molecular functional groups including DNA helicases and mRNA transcriptional regulation. In order to evaluate MYCN binding with respect to other genomic features, we determined the methylation status of all annotated CpG islands and promoter sequences using methylated DNA immunoprecipitation (MeDIP). The integration of MYCN ChIP-chip and MeDIP data revealed a highly significant positive correlation between MYCN binding and DNA hypermethylation. This association was also detected in regions of hemizygous loss, indicating that the observed association occurs on the same homologue. In summary, these findings suggest that MYCN binding occurs more commonly at CATGTG as opposed to the classic CACGTG E-box motif, and that disease associated over expression of MYCN leads to aberrant binding to additional weaker affinity E-box motifs in neuroblastoma. The co-localization of MYCN binding and DNA hypermethylation further supports the dual role of MYCN, namely that of a classical transcription factor affecting the

  15. Regional differences associated with drinking and driving in Brazil Diferenças regionais entre os fatores associados ao beber e dirigir no Brasil

    Directory of Open Access Journals (Sweden)

    Raquel De Boni

    2012-10-01

    Full Text Available OBJECTIVE: To evaluate regional differences and similarities associated with drinking and driving (DUI in the five Brazilian macro-regions. METHOD: A roadside survey was conducted in the 27 Brazilian state capitals. A total of 3,398 drivers were randomly selected and given a structured interview and a breathalyzer test. To determine the predictors of positive blood alcohol concentration (BAC in each region, a MANOVA was performed, and 3 groups were used as follows: 1 North and Northeast, 2 South and Midwest, and 3 Southeast. A Poisson robust regression model was performed to assess the variables associated with positive BAC in each group. RESULTS: Of all surveyed drivers, 2,410 had consumed alcohol in the previous 12 months. Most were male, with a median age of 36. Leisure as the reason for travel was associated with positive BAC in all 3 groups. Low schooling, being older than 30, driving cars or motorcycles and having been given a breathalyzer test at least once in their lives predicted DUI in at least two different groups. CONCLUSIONS: Factors , especially low schooling and leisure as a reason for travel, associated with drinking and driving were similar among regions, although certain region-specific features were observed. This information is important for aiming to reduce DUI in the country.OBJETIVO: Avaliar diferenças e similaridades em relação a beber e dirigir (DUI nas cinco macroregiões brasileiras. MÉTODO: Um roadside survey foi realizado nas 27 capitais brasileiras. Foram selecionados aleatoriamente 3.398 condutores que responderam a uma entrevista estruturada e foram testados com uso de etilômetro. Para a construção de modelos preditivos de alcoolemia positiva (BAC, as regiões foram agrupadas de acordo com sua similaridade, obtida por MANOVA, em: 1 Norte e Nordeste; 2 Sul e Centro-Oeste; 3 Sudeste. Em cada grupo foi realizado um modelo de regressão robusta para estimar as variáveis associadas a BAC. RESULTADOS: Dentre os

  16. Analysis of fracturing in the basalts of the Serra Geral Aquifer and the potential regional recharge of the Guarani Aquifer System; Analise de fraturas dos basaltos do Aquifero Serra Geral e o potencial de recarga regional do Sistema Aquifero Guarani

    Energy Technology Data Exchange (ETDEWEB)

    Fernandes, A. J.; Assis Negri, F. de; Azevedo Sobrino, J. M.; Varnier, C.

    2012-11-01

    The Geological Institute, belonging to the Ministry for the Environment of the State of Sao Paulo, is currently undertaking regional research into vertical groundwater flow through the basalts in the Serra Geral Aquifer (ASG), which influences recharge of the sandstones in the underlying Guarani Aquifer System (SAG) and therefore the quantity of groundwater available and its susceptibility to pollution. The study area corresponds to the outcropping region of the ASG, an area of the state of Sao Paulo that contains important urban centres. The methods used included: (1) field work, focused on characterizing the vertical tectonic structures and the stresses responsible for their origin; and (2) an analysis of the structural data collected, aimed at identifying brittle tectonic events and their influence on groundwater flow. Distinguishing between cooling and tectonic fractures is a relevant aspect of the field work as only the tectonic events are capable of cutting across the vesicular beds, which otherwise form a barrier against vertical flow and block any connection between the aquifers. Three tectonic strike-slip events have been identified, each having generated hybrid tectonic fractures, which, because they involve extension as well as shearing, potentially favour flow. Diagnostic features suggest the occurrence in the south-western zone of the study area of preferential flow along fractures in the direction N70-80W and N60-80E, and secondary ones trending N20W and N20E; in the northeastern zone there is flow along secondary fractures in the direction N15W and N5-10E and in the central zone N40-65W. (Author)

  17. Health assessment for E. I. Dupont Newport Plant Landfill, Newport, Delaware, Region 3. CERCLIS No. DED980555122. Preliminary report

    International Nuclear Information System (INIS)

    1988-01-01

    The E.I. Dupont Newport Plant Landfill, a seven acre site located adjacent to the Dupont Pigment Plant in Newport, Delaware, was used to bury paint pigments (heavy metals and chlorinated solvents) and radioactive materials from 1902 to 1975. The site was closed in 1975, the surface covered, graded and vegetated, and groundwater monitoring wells installed on- and off-site. Heavy metals (cadmium, barium, lead, zinc), and chlorinated solvents (trichloroethylene, tetrachloroethylene) have been measured in groundwater on-site. Radiation levels appear to be close to background. The site is considered to be of potential public health concern because of the risk to human health caused by the possibility of exposure to hazardous substances via groundwater. More information is needed concerning levels of contamination in private wells and the Christina River, the direction of groundwater flow, the size and extent of the groundwater contamination plume, the location of the private wells and the public water supply wells, and the composition of the population down gradient of the site

  18. Sniffer patch laser uncaging response (SPLURgE): an assay of regional differences in allosteric receptor modulation and neurotransmitter clearance.

    Science.gov (United States)

    Christian, Catherine A; Huguenard, John R

    2013-10-01

    Allosteric modulators exert actions on neurotransmitter receptors by positively or negatively altering the effective response of these receptors to their respective neurotransmitter. γ-Aminobutyric acid (GABA) type A ionotropic receptors (GABAARs) are major targets for allosteric modulators such as benzodiazepines, neurosteroids, and barbiturates. Analysis of substances that produce similar effects has been hampered by the lack of techniques to assess the localization and function of such agents in brain slices. Here we describe measurement of the sniffer patch laser uncaging response (SPLURgE), which combines the sniffer patch recording configuration with laser photolysis of caged GABA. This methodology enables the detection of allosteric GABAAR modulators endogenously present in discrete areas of the brain slice and allows for the application of exogenous GABA with spatiotemporal control without altering the release and localization of endogenous modulators within the slice. Here we demonstrate the development and use of this technique for the measurement of allosteric modulation in different areas of the thalamus. Application of this technique will be useful in determining whether a lack of modulatory effect on a particular category of neurons or receptors is due to insensitivity to allosteric modulation or a lack of local release of endogenous ligand. We also demonstrate that this technique can be used to investigate GABA diffusion and uptake. This method thus provides a biosensor assay for rapid detection of endogenous GABAAR modulators and has the potential to aid studies of allosteric modulators that exert effects on other classes of neurotransmitter receptors, such as glutamate, acetylcholine, or glycine receptors.

  19. Amino acid changes within the E protein hinge region that affect dengue virus type 2 infectivity and fusion

    International Nuclear Information System (INIS)

    Butrapet, Siritorn; Childers, Thomas; Moss, Kelley J.; Erb, Steven M.; Luy, Betty E.; Calvert, Amanda E.; Blair, Carol D.; Roehrig, John T.; Huang, Claire Y.-H.

    2011-01-01

    Fifteen mutant dengue viruses were engineered and used to identify AAs in the molecular hinge of the envelope protein that are critical to viral infection. Substitutions at Q52, A54, or E133 reduced infectivity in mammalian cells and altered the pH threshold of fusion. Mutations at F193, G266, I270, or G281 affected viral replication in mammalian and mosquito cells, but only I270W had reduced fusion activity. T280Y affected the pH threshold for fusion and reduced replication in C6/36 cells. Three different mutations at L135 were lethal in mammalian cells. Among them, L135G abrogated fusion and reduced replication in C6/36 cells, but only slightly reduced the mosquito infection rate. Conversely, L135W replicated well in C6/36 cells, but had the lowest mosquito infection rate. Possible interactions between hinge residues 52 and 277, or among 53, 135, 170, 186, 265, and 276 required for hinge function were discovered by sequence analysis to identify compensatory mutations.

  20. Aplicación e información del derecho extranjero en el ámbito interamericano, regional y en el Uruguay

    Directory of Open Access Journals (Sweden)

    Eduardo Tellechea Bergman

    2014-03-01

    Full Text Available El actual incremento de las relaciones privadas internacionales consecuencia, entre otras variables, del desarrollo de los medios de comunicación internacional en sus distintas modalidades y de una paralela flexibilización de las fronteras nacionales, es determinante a nivel jurisdiccional del planteo de diversas cuestiones vinculadas a la aplicación e información del derecho extranjero, que el presente trabajo aborda en su regulación a nivel interamericano y regional, así como en el Derecho Internacional Privado uruguayo.

  1. Study of quasiexclusive neutral meson production in pN interactions at E{sub p} = 70 GeV in the deep fragmentation region

    Energy Technology Data Exchange (ETDEWEB)

    Golovkin, S.V.; Kozhevnikov, A.P.; Kubarovsky, V.P. [Institute for High Energy Physics (IHEP), Protvino (Russian Federation)] [and others; SPHINX Collaboration (IHEP-ITEP)

    1997-11-01

    Quasiexclusive neutral meson production in pN-interactions is studied in experiments with the SPHINX facility operating in a proton beam from the IHEP accelerator (E{sub p}=70 GeV). The cross sections and the parameters of the differential distributions for {pi}{sup 0}, {omega}, {eta} and K{sup 0} production in the deep fragmentation region (x{sub F}>0.79/0.86) are presented. The results show that such proton quasiexclusive reactions with baryon exchange may be promising in searches for exotic mesons. (orig.) 20 refs.

  2. O Brasil e a cooperação em defesa: a construção de uma identidade regional no Atlântico Sul

    Directory of Open Access Journals (Sweden)

    Adriana Erthal Abdenur

    2014-01-01

    Full Text Available O artigo analisa a cooperação que o Brasil vem desenvolvendo ao longo do Atlântico Sul, mostrando que o País vem desempenhando o papel de region-builder na construção de uma identidade sul-atlântica com posição de destaque para si. Tais esforços começam a ser contestados por outros atores de dentro e fora da região.

  3. Nuclear law in motion. Report on the 15th regional meeting of the German section of AIDN/INLA e.V

    International Nuclear Information System (INIS)

    Feldmann, Ulrike

    2017-01-01

    For the 15th time the German National Group of the Association Internationale du Droit Nucleaire/International Nuclear Law Association (AIDN/IN-LA) e.V. organised a regional conference. 90 participants from 15 countries, including representatives of Euratom and OECD/NEA, met in Bonn on 28 and 29 September to exchange views on current issues of nuclear law. The Rhine, which was in sight of the conference centre and connects countries, provided an excellent backdrop not only for the conference that connects nations, but also for the title of the conference ''Atomic Energy Law in Motion'' and for various lectures on nuclear transport.

  4. Contestação de normas e ameaça à paz e à segurança regional e internacional: a facilidade excessiva de acesso a armas Norm contestation and threat to regional and international peace and security: excessive ease of access to arms

    Directory of Open Access Journals (Sweden)

    Denise Garcia

    2011-12-01

    Full Text Available A facilidade de acesso a armas, pelos governos e atores não governamentais afins, exacerba os conflitos, destrói os acordos de paz frágeis e facilita a perpetração de violações dos direitos humanos e crimes hediondos contra a humanidade. Agravando isso, o comércio de armas está fora do alcance do direito internacional, ou seja, não existe um tratado global internacional juridicamente vinculativo que regulamente todos os aspectos da transferência de armas. A prática de transferência de armas para atores não estatais sem critérios em relação aos usuários finais é uma característica recorrente do comércio mundial de armas e, geralmente, tem consequências deletérias. Estas são percebidas nos conflitos prolongados no Afeganistão, na República Democrática do Congo, no Sudão, no Chifre da África, no Oriente Médio e mais recentemente na Síria e na Líbia, entre muitos outros. O presente artigo analisa uma tentativa contestada na construção de normas internacionais para conter uma prática internacional de longa data - a da transferência de armas para atores não estatais - e suas implicações para a segurança internacional, direito internacional e formulação de políticas a nível multilateral. No entanto, diferente dos construtivistas, examina uma norma que, apesar de difundida em diferentes contextos regionais, não conseguiu encontrar validade jurídica como uma realidade normativa internacional.The ease of access to arms, by governments and non-government actors alike, exacerbates conflicts, destroys fragile peace agreements, and facilitates the perpetration of violations of human rights and egregious crimes against humanity. Compounding this, the arms trade is out of the purview of International Law; that is, there is no comprehensive legally binding international treaty regulating all aspects of arms transfers. The practice of transferring arms to non-state actors with no criteria regarding the end users is a

  5. Nuclear law in motion. Report on the 15th regional meeting of the German section of AIDN/INLA e.V; Atomrecht in Bewegung. Bericht ueber die 15. Regionaltagung der Deutschen Landesgruppe der AIDN/INLA e.V.

    Energy Technology Data Exchange (ETDEWEB)

    Feldmann, Ulrike

    2017-11-15

    For the 15th time the German National Group of the Association Internationale du Droit Nucleaire/International Nuclear Law Association (AIDN/IN-LA) e.V. organised a regional conference. 90 participants from 15 countries, including representatives of Euratom and OECD/NEA, met in Bonn on 28 and 29 September to exchange views on current issues of nuclear law. The Rhine, which was in sight of the conference centre and connects countries, provided an excellent backdrop not only for the conference that connects nations, but also for the title of the conference ''Atomic Energy Law in Motion'' and for various lectures on nuclear transport.

  6. Energy model in regional energy system; Modello computazionale dei flussi di enegia, massa e materia in un sistema energetico regionale per la valutazione delle emissioni

    Energy Technology Data Exchange (ETDEWEB)

    Mura, P.G.; Baccoli, R.; Carlini, U.; Innamorati, R.; Mariotti, S. [Cagliari Univ., Cagliari (Italy). Sezione Fisica Tecnica ed Energetica Facolta' d' Ingegneria

    2005-09-01

    In this report is presented a computational model for analysis of energy, materials and mass flux in a complex energy system, at regional scale level. Specifically is described a calculation model of electric power generation for emission forecasting of CO{sub 2}, SO{sub x}, NO{sub x}, particulate matter, ashes, limestone, chalks. [Italian] Dopo aver ricordato che nel campo della Fisica Tecnica ambientale acquista sempre piu' importanza l'analisi dei processi che interessano l'ambiente esterno in stretto rapporto con i processi di conversione ed uso dell'energia e con le condizioni di benessere nell'ambiente interno, in questa memoria viene presentato un modello computazionale per l'analisi dei flussi di energia, massa e materia che hanno luogo in un sistema energetico complesso esteso al territorio di una regione. In particolare viene descritto il modello di calcolo del sottosistema di generazione elettrica finalizzato alla previsione delle emissioni nocive riversate nell'ambiente naturale quali CO{sub 2}, SO{sub x}, NO{sub x}, polveri, ceneri, calcare, gessi.

  7. Polarized BRDF measurement of steel E235B in the near-infrared region: Based on a self-designed instrument with absolute measuring method

    Science.gov (United States)

    Liu, Yanlei; Yu, Kun; Liu, Zilong; Zhao, Yuejin; Liu, Yufang

    2018-06-01

    The spectral bidirectional reflectance distribution (BRDF) offers a complete description of the optical properties of the opaque material. Numerous studies on BRDF have been conducted for its important role in scientific research and industrial production. However, most of these studies focus on the visible region and unpolarized BRDF, and the spectral polarized BRDF in the near-infrared region is rarely reported. In this letter, we propose an absolute method to measure the spectral BRDF in the near-infrared region, and the detailed derivation is presented. A self-designed instrument is set up for the absolute measurement of BRDF. The reliability of this method is verified by comparing the experimental data of the three metal (aluminum, silver and gold) mirrors with the reference data. The in-plane polarized BRDF of steel E235B are measured, and the influence of incident angle and roughness on the BRDF are discussed. The degree of linear polarization (DOLP) are determined based on the polarized BRDF. The results indicate that both the roughness and incident angle have distinct influence on the BRDF and DOLP.

  8. Regional climate modeling over the Maritime Continent: Assessment of RegCM3-BATS1e and RegCM3-IBIS

    Science.gov (United States)

    Gianotti, R. L.; Zhang, D.; Eltahir, E. A.

    2010-12-01

    Despite its importance to global rainfall and circulation processes, the Maritime Continent remains a region that is poorly simulated by climate models. Relatively few studies have been undertaken using a model with fine enough resolution to capture the small-scale spatial heterogeneity of this region and associated land-atmosphere interactions. These studies have shown that even regional climate models (RCMs) struggle to reproduce the climate of this region, particularly the diurnal cycle of rainfall. This study builds on previous work by undertaking a more thorough evaluation of RCM performance in simulating the timing and intensity of rainfall over the Maritime Continent, with identification of major sources of error. An assessment was conducted of the Regional Climate Model Version 3 (RegCM3) used in a coupled system with two land surface schemes: Biosphere Atmosphere Transfer System Version 1e (BATS1e) and Integrated Biosphere Simulator (IBIS). The model’s performance in simulating precipitation was evaluated against the 3-hourly TRMM 3B42 product, with some validation provided of this TRMM product against ground station meteorological data. It is found that the model suffers from three major errors in the rainfall histogram: underestimation of the frequency of dry periods, overestimation of the frequency of low intensity rainfall, and underestimation of the frequency of high intensity rainfall. Additionally, the model shows error in the timing of the diurnal rainfall peak, particularly over land surfaces. These four errors were largely insensitive to the choice of boundary conditions, convective parameterization scheme or land surface scheme. The presence of a wet or dry bias in the simulated volumes of rainfall was, however, dependent on the choice of convection scheme and boundary conditions. This study also showed that the coupled model system has significant error in overestimation of latent heat flux and evapotranspiration from the land surface, and

  9. The first coordinated observations of mid-latitude E-region quasi-periodic radar echoes and lower thermospheric 557.7-nm airglow

    Directory of Open Access Journals (Sweden)

    T. Ogawa

    2005-10-01

    Full Text Available We present the first coordinated observations of quasi-periodic (QP radar echoes from sporadic-E (Es field-aligned irregularities (FAIs, OI 557.7-nm airglow, and neutral winds in a common volume over Shigaraki, Japan (34.9° N, 136.1° E on the night of 5 August 2002 during the SEEK-2 campaign. QP echo altitudes of 90-110 km were lower than usual by 10 km, enabling us to make a detailed comparison among QP echoes, airglow intensity, and neutral wind at around 96 km altitude. Eastward movement of the QP echo regions is consistent with the motions of neutral winds, airglow structures, and FAIs, suggesting that the electrodynamics of Es-layers is fundamentally controlled by the neutral atmospheric dynamics. During the QP echo event, the echo altitudes clearly went up (down in harmony with an airglow enhancement (subsidence that also moved to the east. This fact suggests that the eastward-moving enhanced airglow region included an upward (downward component of neutral winds to raise (lower the altitude of the wind-shear node responsible for the Es formation. The airglow intensity, echo intensity, and Doppler velocity of FAIs at around 96 km altitude fluctuated with periods from 10 min to 1h, indicating that these parameters were modulated with short-period atmospheric disturbances. Some QP echo regions below 100km altitude contained small-scale QP structures in which very strong neutral winds exceeding 100 m/s existed. The results are compared with recent observations, theories, and simulations of QP echoes. Keywords. Ionosphere (Ionosphere-atmosphere interactions; Ionospheric irregularities; Mid-latitude ionosphere

  10. Termorregulação e desempenho de tourinhos Sindi e Guzerá, no agreste paraibano Thermoregulation and performance of Sind and Guzera young bulls in 'Agreste' region of Paraiba state

    Directory of Open Access Journals (Sweden)

    Dermeval A. Furtado

    2012-09-01

    Full Text Available Neste trabalho objetivou-se avaliar os índices bioclimáticos que influenciam as varáveis fisiológicas, desempenho e consumo de nutrientes de tourinhos das raças Gir e Guzerá. O estudo foi realizado na Estação Experimental de Alagoinha/EMEPA-PB, no município de Alagoinha, no agreste paraibano, Brasil, utilizando-se 16 tourinhos das raças Sindi e Guzerá (8 animais de cada raça, com média de 31,5 ± 1,5 meses de idade, mantidos confinados. O delineamento estatístico utilizado foi o de blocos inteiramente casualizados, com 8 repetições, em parcelas subdivididas, com raça na parcela principal e horários (6, 12 e 16 h na subparcela. A temperatura retal, frequência respiratória e temperatura superficial dos animais se mantiveram dentro da faixa considerada normal para a espécie bovina. Não houve influência negativa no consumo de nutrientes e os animais tiveram um desempenho em ganho de peso acima do esperado, demonstrando que estão adaptados às condições de Nordeste brasileiro, já que não houve alterações em seus parâmetros fisiológicos, considerados dentro da faixa normal e ainda apresentaram excelente desempenho produtivo e de consumo de nutrientes.The objective of this study was to evaluate the bioclimatic indices that influence physiological variables, performance and nutrient intake by Gir and Guzera young bulls. The work was conducted at the Experimental Station of Alagoinha/EMEPA-PB in Alagoinha town in 'Agreste' region of Paraiba state, Brazil, using 16 young bulls of Sind and Guzera breeds (8 animals of each breed, with a mean 31.5 ± 1.5 months of age, kept under confined conditions. The statistical design used was randomized blocks with eight replications in split plot with breed in the main plot and time (6, 12 and 16 h as subplots. Rectal temperature, respiratory rate and surface temperature of the animals remained within the normal range for the bovine species. There was no negative influence on food

  11. A Influência da Imersão Institucional e Regional na Cooperação entre Pesquisadores no Brasil.

    Directory of Open Access Journals (Sweden)

    Rossoni, Luciano

    2009-06-01

    Full Text Available A análise do campo científico como uma rede social vem ampliando o entendimento das relações entre pesquisadores como atividade social. Além do significado dado pelos relacionamentos entre pares, questões estruturais emergem, fomentando explicações sobre como níveis sociais mais amplos condicionam as relações de co-autoria. Buscando contribuir para essa linha de estudos, o objetivo do presente artigo é analisar como as relações entre pesquisadores da área de administração da informação no Brasil são condicionadas pela imersão institucional e regional. Para tanto, foi utilizado o método da análise de redes sociais, mais especificamente a técnica de generalized blockmodels para testar modelos relacionais de homofilia e centro-periferia. Verificou-se que todos os modelos relacionados ao padrão de homofilia foram significativos e que o condicionamento devido à instituição foi mais homogêneo do que o decorrente das unidades federativas. Diferentemente do esperado, os padrões do tipo centro-periferia mostraram-se pouco significativos. Mas, pautando-se no resultado que foi significativo, verifica-se que existe algum mecanismo de seleção privilegiado por pesquisadores que fazem parte de algumas regiões, seja pelo acesso a recursos e informações, seja pela existência de programas mais tradicionais. Adicionalmente, o estudo aponta para implicações teóricas e práticas, destacando possibilidades de estudos futuros.

  12. Measurement of target and double-spin asymmetries for the e ⃗p ⃗→e π+(n ) reaction in the nucleon resonance region at low Q2

    Science.gov (United States)

    Zheng, X.; Adhikari, K. P.; Bosted, P.; Deur, A.; Drozdov, V.; El Fassi, L.; Kang, Hyekoo; Kovacs, K.; Kuhn, S.; Long, E.; Phillips, S. K.; Ripani, M.; Slifer, K.; Smith, L. C.; Adikaram, D.; Akbar, Z.; Amaryan, M. J.; Anefalos Pereira, S.; Asryan, G.; Avakian, H.; Badui, R. A.; Ball, J.; Baltzell, N. A.; Battaglieri, M.; Batourine, V.; Bedlinskiy, I.; Biselli, A. S.; Briscoe, W. J.; Bültmann, S.; Burkert, V. D.; Carman, D. S.; Celentano, A.; Chandavar, S.; Charles, G.; Chen, J.-P.; Chetry, T.; Choi, Seonho; Ciullo, G.; Clark, L.; Colaneri, L.; Cole, P. L.; Compton, N.; Contalbrigo, M.; Crede, V.; D'Angelo, A.; Dashyan, N.; De Vita, R.; De Sanctis, E.; Djalali, C.; Dodge, G. E.; Dupre, R.; Egiyan, H.; El Alaoui, A.; Elouadrhiri, L.; Eugenio, P.; Fanchini, E.; Fedotov, G.; Fersch, R.; Filippi, A.; Fleming, J. A.; Gevorgyan, N.; Ghandilyan, Y.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Gleason, C.; Golovach, E.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guler, N.; Guo, L.; Hanretty, C.; Harrison, N.; Hattawy, M.; Hicks, K.; Holtrop, M.; Hughes, S. M.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Jenkins, D.; Jiang, H.; Jo, H. S.; Joosten, S.; Keller, D.; Khachatryan, G.; Khandaker, M.; Kim, A.; Kim, W.; Klein, F. J.; Kubarovsky, V.; Lanza, L.; Lenisa, P.; Livingston, K.; MacGregor, I. J. D.; Markov, N.; McKinnon, B.; Mirazita, M.; Mokeev, V.; Movsisyan, A.; Munevar, E.; Munoz Camacho, C.; Murdoch, G.; Nadel-Turonski, P.; Net, L. A.; Ni, A.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Osipenko, M.; Ostrovidov, A. I.; Paolone, M.; Paremuzyan, R.; Park, K.; Pasyuk, E.; Peng, P.; Pisano, S.; Pogorelko, O.; Price, J. W.; Puckett, A. J. R.; Raue, B. A.; Rizzo, A.; Rosner, G.; Rossi, P.; Roy, P.; Sabatié, F.; Salgado, C.; Schumacher, R. A.; Sharabian, Y. G.; Skorodumina, Iu.; Smith, G. D.; Sokhan, D.; Sparveris, N.; Stankovic, I.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tian, Ye; Ungaro, M.; Voskanyan, H.; Voutier, E.; Walford, N. K.; Watts, D. P.; Wei, X.; Weinstein, L. B.; Wood, M. H.; Zachariou, N.; Zhang, J.; Zonta, I.; CLAS Collaboration

    2016-10-01

    We report measurements of target- and double-spin asymmetries for the exclusive channel e ⃗p ⃗→e π+(n ) in the nucleon resonance region at Jefferson Lab using the CEBAF Large Acceptance Spectrometer (CLAS). These asymmetries were extracted from data obtained using a longitudinally polarized NH3 target and a longitudinally polarized electron beam with energies 1.1, 1.3, 2.0, 2.3, and 3.0 GeV. The new results are consistent with previous CLAS publications but are extended to a low Q2 range from 0.0065 to 0.35 (GeV/c ) 2 . The Q2 access was made possible by a custom-built Cherenkov detector that allowed the detection of electrons for scattering angles as low as 6∘. These results are compared with the unitary isobar models JANR and MAID, the partial-wave analysis prediction from SAID, and the dynamic model DMT. In many kinematic regions our results, in particular results on the target asymmetry, help to constrain the polarization-dependent components of these models.

  13. Initial results from SKiYMET meteor radar at Thumba (8.5°N, 77°E): 2. Gravity wave observations in the MLT region

    Science.gov (United States)

    Kumar, Karanam Kishore; Antonita, T. Maria; Shelbi, S. T.

    2007-12-01

    In the present communication, allSKy interferometric METeor (SKiYMET) radar observations of gravity wave activity in the mesosphere lower thermosphere (MLT) region over Thumba (8.5°N, 77°E) are presented. The present meteor radar system provides hourly zonal and meridional winds in the MLT region, which can be readily used for studying the tides, planetary waves, gravity waves of periods 2-6 hours, and other long period oscillations in this region. However, these hourly winds are not sufficient for studying short period gravity waves having periods less than an hour, which demand high temporal resolution measurements. Even though the winds are estimated on an hourly basis, information such as zenith angle, azimuth angle, and radial velocity of each detected meteor are archived. Using these details of the meteor, an algorithm is developed to obtain the 15-min temporal resolution wind data. The output of the algorithm is compared with hourly wind data, and it showed a good agreement during the high meteor shower periods. Most of the times high meteor counts are observed during late night and early morning hours (local) over this latitude. Continuous wind measurements during the high meteor shower periods are used for studying the gravity wave activity in the MLT region. As the wave activity is intermittent and nonstationary, wavelet analysis has been used for delineating the wave features. The results showed the upward propagating intermittent gravity waves with periods 1-2 and 4-5 hours. The new aspect of the present communication is the usage of meteor radar for gravity wave studies for the first time over this latitude and studying their seasonal variability.

  14. L' influenza nella regione Lazio dal 1999 al 2003: casi di sindrome influenzale, ricoveri ospedalieri per malattie respiratorie e coperture vaccinali

    Directory of Open Access Journals (Sweden)

    A. Pasquarella

    2003-05-01

    Full Text Available

    Obiettivi: 1 Descrivere l’andamento dei ricoveri ospedalieri per patologie respiratorie acute e croniche concomitanti alle epidemie stagionali da virus influenzale dal 1999 al 2003, in relazione con la segnalazione dei casi di sindrome influenzale (ILI da parte dei medici sentinella. 2 Misurare l’eccesso dell’ospedalizzazione influenza-correlata nelle diverse fasce di età rispetto ai periodi non epidemici. 3 Analizzare le modificazioni del ricorso al ricovero ospedaliero in relazione al tasso di copertura della vaccinazione antinfluenzale nella popolazione anziana, su scala regionale e nelle diverse ASL.

    Metodi: sono stati estratti dal Sistema Informativo
    Ospedaliero i ricoveri per patologie respiratorie
    influenza-correlate (codici ICD9-CM: 480-487; 460-
    466; 490-496 relativi agli anni 1999-2003.
    L’incidenza di ILI è stata stimata sulla base delle
    segnalazioni dei medici sentinella afferenti alla
    rete FLU-ISS dell’Istituto Superiore di Sanità.

    Per il calcolo dei tassi di copertura è stato utilizzato l’archivio
    nominativo dei soggetti vaccinati contro l’influenza,
    attivo nella regione Lazio dal 1999. Nel periodo considerato sono stati messi in relazione i tassi di ospedalizzazione età-specifici, le incidenze di ILI e le coperture vaccinali. L’eccesso di ospedalizzazione è stato misurato confrontando i tassi relativi ai periodi epidemici e non epidemici.

    Risultati: i tassi di ospedalizzazione per malattie respiratorie sono risultati costantemente superiori nei periodi di maggiore circolazione virale, in particolare negli ultrasessantaquattrenni. Con il progressivo aumento del tasso di copertura vaccinale regionale (da circa il 25% della stagione 1999-2000 a oltre il 60% della stagione 2002-2003 non si è registrata una corrispondente diminuzione dei ricoveri ospedalieri per patologie influenza-correlate.
    L

  15. Teaching Astronomy through e-learning in Poland: Astronomical Education in teacher training conducted by the Regional Teacher Training Center in Skierniewice

    Science.gov (United States)

    Dabrowska, A. E.

    2014-12-01

    Regional Teacher Training Centre (RTTC) in Skierniewice is one of 49 public, accredited institutions in Poland carrying out it statutory goals at the regional level. It has been operating since 1989 and is responsible for organizing of support of schools, institutions, networks of teachers for cooperation and self-education, organizing various forms of in-service training and disseminating examples of good practice. It also has rich experience in teaching by using modern Interactive Computer Technology (ICT) tools and e-learning platform. I present examples about teaching of Astronomical issues through teacher training both as hands on workshops as well as through e-learning. E-learning is playing an important role in organizing educational activities not only in the field of modern didactic but also in learning Science subjects. Teachers find e-learning as a very economical, easy and convenient way of learning and developing their knowledge and skills. Moreover, they are no longer afraid of using new ICT tools and programs which help them to cooperate with students effectively. Since 2011 RTTC in Skierniewice has been an organizer of many on-line in-service programs for teachers, in learning Science. Some of them are organized as blended-learning programs which allow teachers to participate first in hands on activities then continue learning on the Moodle platform. These courses include two 15 and 30-hours of Astronomical topics. Teachers have the opportunity to gain knowledge and receive materials not only about the Universe and the Solar System but also can learn to use tools like Stellarium, Celestia, WorldWide Telescope, Your Sky and other tools. E-learning modules consist of both publishing learning materials in various forms, eg. PowerPoint Presentations, Word & PDF materials, web sites, publications, working sheets as well as practical duties like participation in chats, forums, tasks, Wiki, group workshop. Teachers use these materials for extending their

  16. Impact of improved Greenland ice sheet surface representation in the NASA GISS ModelE2 GCM on simulated surface mass balance and regional climate

    Science.gov (United States)

    Alexander, P. M.; LeGrande, A. N.; Fischer, E.; Tedesco, M.; Kelley, M.; Schmidt, G. A.; Fettweis, X.

    2017-12-01

    Towards achieving coupled simulations between the NASA Goddard Institute for Space Studies (GISS) ModelE2 general circulation model (GCM) and ice sheet models (ISMs), improvements have been made to the representation of the ice sheet surface in ModelE2. These include a sub-grid-scale elevation class scheme, a multi-layer snow model, a time-variable surface albedo scheme, and adjustments to parameterization of sublimation/evaporation. These changes improve the spatial resolution and physical representation of the ice sheet surface such that the surface is represented at a level of detail closer to that of Regional Climate Models (RCMs). We assess the impact of these changes on simulated Greenland Ice Sheet (GrIS) surface mass balance (SMB). We also compare ModelE2 simulations in which winds have been nudged to match the European Center for Medium-Range Weather Forecasts (ECMWF) ERA-Interim reanalysis with simulations from the Modèle Atmosphérique Régionale (MAR) RCM forced by the same reanalysis. Adding surface elevation classes results in a much higher spatial resolution representation of the surface necessary for coupling with ISMs, but has a negligible impact on overall SMB. Implementing a variable surface albedo scheme increases melt by 100%, bringing it closer to melt simulated by MAR. Adjustments made to the representation of topography-influenced surface roughness length in ModelE2 reduce a positive bias in evaporation relative to MAR. We also examine the impact of changes to the GrIS surface on regional atmospheric and oceanic climate in coupled ocean-atmosphere simulations with ModelE2, finding a general warming of the Arctic due to a warmer GrIS, and a cooler North Atlantic in scenarios with doubled atmospheric CO2 relative to pre-industrial levels. The substantial influence of changes to the GrIS surface on the oceans and atmosphere highlight the importance of including these processes in the GCM, in view of potential feedbacks between the ice sheet

  17. Identification of highly deformed even–even nuclei in the neutron- and proton-rich regions of the nuclear chart from the B(E2)↑ and E2 predictions in the generalized differential equation model

    International Nuclear Information System (INIS)

    Nayak, R.C.; Pattnaik, S.

    2015-01-01

    We identify here the possible occurrence of large deformations in the neutron- and proton-rich (n-rich and p-rich) regions of the nuclear chart from extensive predictions of the values of the reduced quadrupole transition probability B(E2)↑ for the transition from the ground state to the first 2 + state and the corresponding excitation energy E2 of even–even nuclei in the recently developed generalized differential equation (GDE) model exclusively meant for these physical quantities. This is made possible from our analysis of the predicted values of these two physical quantities and the corresponding deformation parameters derived from them such as the quadrupole deformation β 2 , the ratio of β- 2 to the Weisskopf single-particle β 2(sp) and the intrinsic electric quadrupole moment Q 0 , calculated for a large number of both known as well as hitherto unknown even–even isotopes of oxygen to fermium (0 to FM; Z = 8 – 100). Our critical analysis of the resulting data convincingly support possible existence of large collectivity for the nuclides 30,32 Ne, 34 Mg, 60 Ti, 42,62,64 Cr, 50,68 Fe, 52,72 Ni, 72,70,96 Kr, 74,76 Sr, 78,80,106,108 Zr, 82,84,110,112 Mo, 140 Te, 144 Xe, 148 Ba, 122 Ce, 128,156 Nd, 130,132,158,160 Sm and 138,162,164,166 Gd, whose values of β 2 are found to exceed 0.3 and even 0.4 in some cases. Our findings of large deformations in the exotic n-rich regions support the existence of another “island of inversion” in the heavy-mass region possibly caused by breaking of the N = 70 subshell closure. (author)

  18. Modulation of thyroid hormone receptor transactivation by the early region 1A (E1A-like inhibitor of differentiation 1 (EID1

    Directory of Open Access Journals (Sweden)

    Diana Vargas

    2008-01-01

    Full Text Available Transcriptional activation (TA mediated by the effect of thyroid hormones on target genes requires co-activator proteins such as the early region 1A (E1A associated 300 kDa binding protein (p300 and the cAMP response element binding protein (CREB binding protein (CBP, known as the p300/CBP complex, which acetylate histones 3 and 4 to allow transcriptional machinery access to the target gene promoter. Little is known on the role of p300 in thyroid hormone receptor (TR mediated TA but the E1A-like inhibitor of differentiation 1 (EID1, an inhibitor of p300 histone acetyltransferase (HAT, is a functional homolog of E1A and may inhibit myogenic differentiation factor D (MyoD transcriptional activity and reduces muscle cell differentiation. We evaluated the influence of EID1 on TR-mediated transcriptional activity using transfection and mammalian two-hybrid studies to show that EID1 may partially reduces TA activity of the TR receptor, probably due to p300 blockage since EID1 mutants cannot reduce TR-mediated TA. The EID1 does not affect the function of p160 co-activator proteins (160 kDa proteins of steroid receptor co-activators and is functionally independent of co-repressor proteins or TR binding. Summarizing, EID1 reduces TR-mediated transcriptional activity by blocking p300 and may play an important role in thyroid receptor activity in muscle and other tissues.

  19. Critical Parameters and Critical-Region (p,ρ ,T) Data of trans-1,1,1,3-Tetrafluorobut-2-ene [HFO-1354mzy(E)

    Science.gov (United States)

    Kimura, Takeru; Kayukawa, Yohei; Miyamoto, Hiroyuki; Saito, Kiyoshi

    2017-08-01

    This study presents the experimental measurement of the pρ T properties and critical parameters of a low GWP type refrigerant, trans-1,1,1,3-Tetrafluorobut-2-ene (HFO-1354mzy(E)). The sample purity of the substance was 99 area %. p ρ T property measurements and visual observations of the meniscus of HFO-1354mzy(E) were carried out using a metal-bellows volumometer with an optical cell. The critical temperature was determined by observation of the critical opalescence. The critical pressure and critical density were determined as the inflection point of the isothermal p ρ T property data at the critical temperature. For more precise clarification of the thermodynamic surface in the vicinity of the critical point, additional p ρ T property measurements were carried out on three isotherms in the supercritical region. The expanded uncertainties (k = 2) in the temperature, pressure, and density measurements were estimated to be less than 3 mK, 1.2 kPa, and 0.32 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. The expanded uncertainties of the critical parameters were estimated to be less than 13 mK, 1.4 kPa, and 2.3 \\hbox {kg} \\cdot \\hbox {m}^{-3}, respectively. These values are the first reported for HFO-1354mzy(E) and are necessary for the development of its equation of state in the near future.

  20. Fatores associados com o comportamento sexual e reprodutivo entre adolescentes das regiões Sudeste e Nordeste do Brasil Factors associated with sexual and reproductive behavior among adolescents from the Northeast and Southeast regions of Brazil

    Directory of Open Access Journals (Sweden)

    Iúri da Costa Leite

    2004-04-01

    Full Text Available Neste artigo são analisados os fatores associados com o comportamento sexual e reprodutivo das adolescentes das regiões Nordeste e Sudeste do Brasil. A análise é implementada focando três dimensões deste processo: a iniciação sexual, o uso de métodos anticoncepcionais na primeira relação sexual e fecundidade. Modelos hierárquicos são implementados, pois adolescentes selecionadas de uma mesma comunidade devem ter comportamento sexual e reprodutivo mais semelhantes do que adolescentes selecionadas de áreas diferentes. O nível educacional da adolescente revelou-se o fator de risco mais importante nas três análises implementadas. Adolescentes com cinco ou mais anos de escolaridade são menos prováveis de ter a primeira relação sexual na adolescência; mais propensas a usar métodos anticoncepcionais nesta relação e apresentam menores riscos de ter filhos, quando comparadas com adolescentes com menos de cinco anos de escolaridade.This article calls attention to factors associated with sexual and reproductive behavior among adolescents from the Northeast and Southeast regions of Brazil. The analyses focus on three dimensions of this process: sexual initiation, use of contraceptives in the first sexual relationship, and fertility. Hierarchical models are implemented, because adolescents selected from the same community are more likely to have similar sexual and reproductive behavior than those from different communities. Level of schooling was the most important risk factor in the three analyses. Girls with 5 or more years of schooling were less likely to have their first sexual relationship during adolescence and more likely to use contraceptive methods in this relationship, besides demonstrating less risk of having children than their counterparts with less than 5 years of schooling.

  1. Son huasteco e identidad regional

    Directory of Open Access Journals (Sweden)

    Rosa María Bonilla Burgos

    2013-04-01

    Full Text Available La población de la región Huasteca es partícipe de manifestaciones musicales en diferentes ámbitos, lo cual permite reconocer que entre todos los géneros utilizados destaca el son huasteco y su correspondiente bailable llamado huapango. Dichas expresiones musicales se impregnan de los ambientes tanto físico como social que viven constantemente. Es a través de las letras de los sones huastecos que se desarrolla el mecanismo para reflejar el mundo natural que perciben, y los acontecimientos que les suceden, cobrando una importancia que deriva en una identificación que trasciende. Conciben su entorno y lo refieren con sentido de pertenencia-apropiación, que les permite recrear su vida y fundirse en una identificación cultural a la que se le llamará “identidad regional”. La relevancia de considerar una expresión musical de estas características radica en que se preserva y enriquece constantemente unificando un área de México que no necesariamente corresponde a límites políticos establecidos en las diferentes etapas históricas.

  2. Diffuse alopecia areata is associated with intense inflammatory infiltration and CD8+ T cells in hair loss regions and an increase in serum IgE level

    Directory of Open Access Journals (Sweden)

    Ying Zhao

    2012-01-01

    Full Text Available Background: Mechanism leading to an abrupt hair loss in diffuse alopecia areata (AA remains unclear. Aims: To explore the characteristics of diffuse AA and possible factors involved in its pathogenesis. Methods: Clinical and laboratory data of 17 diffuse AA patients and 37 patchy AA patients were analyzed retrospectively. Serum IgE level was evaluated in all diffuse and patchy AA patients, as well as 27 healthy subjects without hair loss to serve as normal control. Univariate analysis was performed using Fisher′s exact test and Wilcoxon rank-sum test. Associations between inflammatory cell infiltration and laboratory values were analyzed using Spearman rank correlation test. Results: The mean age of patients with diffuse AA was 27 years with a mean disease duration of 1.77 months. All of them presented in spring or summer with an acute onset of diffuse hair loss preceded by higher incidence of scalp pruritus. Although no statistically significant difference on the incidence of atopic disease among three groups has been found, serum IgE level in diffuse AA was higher than that in healthy controls, but was comparable to that in patchy AA group. Histopathology of lesional scalp biopsies showed more intense infiltration comprising of mononuclear cells, eosinophils, CD3 + , and CD8 + T cells around hair bulbs in diffuse AA group than in patchy AA group. Moreover, IgE level in diffuse AA patients positively correlated with intensity of infiltration by mononuclear cells, eosinophils, and CD8 + T cells. Conclusions: Hypersensitivity may be involved in pathogenesis of diffuse AA. The acute onset of diffuse AA may be related to intense local inflammatory infiltration of hair loss region and an increase in serum IgE level.

  3. Self-organization of large-scale ULF electromagnetic wave structures in their interaction with nonuniform zonal winds in the ionospheric E region

    International Nuclear Information System (INIS)

    Aburjania, G. D.; Chargazia, Kh. Z.

    2011-01-01

    A study is made of the generation and subsequent linear and nonlinear evolution of ultralow-frequency planetary electromagnetic waves in the E region of a dissipative ionosphere in the presence of a nonuniform zonal wind (a sheared flow). Hall currents flowing in the E region and such permanent global factors as the spatial nonuniformity of the geomagnetic field and of the normal component of the Earth’s angular velocity give rise to fast and slow planetary-scale electromagnetic waves. The efficiency of the linear amplification of planetary electromagnetic waves in their interaction with a nonuniform zonal wind is analyzed. When there are sheared flows, the operators of linear problems are non-self-conjugate and the corresponding eigenfunctions are nonorthogonal, so the canonical modal approach is poorly suited for studying such motions and it is necessary to utilize the so-called nonmodal mathematical analysis. It is shown that, in the linear evolutionary stage, planetary electromagnetic waves efficiently extract energy from the sheared flow, thereby substantially increasing their amplitude and, accordingly, energy. The criterion for instability of a sheared flow in an ionospheric medium is derived. As the shear instability develops and the perturbation amplitude grows, a nonlinear self-localization mechanism comes into play and the process ends with the self-organization of nonlinear, highly localized, solitary vortex structures. The system thus acquires a new degree of freedom, thereby providing a new way for the perturbation to evolve in a medium with a sheared flow. Depending on the shape of the sheared flow velocity profile, nonlinear structures can be either purely monopole vortices or vortex streets against the background of the zonal wind. The accumulation of such vortices can lead to a strongly turbulent state in an ionospheric medium.

  4. eEcoLiDAR, eScience infrastructure for ecological applications of LiDAR point clouds: reconstructing the 3D ecosystem structure for animals at regional to continental scales

    Directory of Open Access Journals (Sweden)

    W. Daniel Kissling

    2017-07-01

    Full Text Available The lack of high-resolution measurements of 3D ecosystem structure across broad spatial extents impedes major advancements in animal ecology and biodiversity science. We aim to fill this gap by using Light Detection and Ranging (LiDAR technology to characterize the vertical and horizontal complexity of vegetation and landscapes at high resolution across regional to continental scales. The newly LiDAR-derived 3D ecosystem structures will be applied in species distribution models for breeding birds in forests and marshlands, for insect pollinators in agricultural landscapes, and songbirds at stopover sites during migration. This will allow novel insights into the hierarchical structure of animal-habitat associations, into why animal populations decline, and how they respond to habitat fragmentation and ongoing land use change. The processing of these massive amounts of LiDAR point cloud data will be achieved by developing a generic interactive eScience environment with multi-scale object-based image analysis (OBIA and interpretation of LiDAR point clouds, including data storage, scalable computing, tools for machine learning and visualisation (feature selection, annotation/segmentation, object classification, and evaluation, and a PostGIS spatial database. The classified objects will include trees, forests, vegetation strata, edges, bushes, hedges, reedbeds etc. with their related metrics, attributes and summary statistics (e.g. vegetation openness, height, density, vertical biomass distribution etc.. The newly developed eScience tools and data will be available to other disciplines and applications in ecology and the Earth sciences, thereby achieving high impact. The project will foster new multi-disciplinary collaborations between ecologists and eScientists and contribute to training a new generation of geo-ecologists.

  5. Polybrominated diphenyl ethers in road and farmland soils from an e-waste recycling region in Southern China: Concentrations, source profiles, and potential dispersion and deposition

    International Nuclear Information System (INIS)

    Luo Yong; Luo Xiaojun; Lin Zhen; Chen Shejun; Liu Juan; Mai Bixian; Yang Zhongyi

    2009-01-01

    The present study analyzed road soils collected near the dismantling workshops of an e-waste recycling region in South China to determine the PBDE profiles. Farmland soils at a distance of about 2 km from the dismantling workshops were also collected to evaluate the potential dispersion and deposition of PBDEs in the surrounding environment. Total PBDE concentrations ranged from 191 to 9156 ng/g dry weight in road soils and from 2.9 to 207 ng/g dry weight in farmland soils, respectively. Three PBDE source profiles were observed from the road soils by principal component analysis, and were compared with the congener patterns in different technical products. Elevated abundances of octa- and nona-congeners were found in the 'deca-' derived PBDEs as compared with the deca-BDE products. The results in this study suggest that debromination of BDE 209 may have occurred during the use of electric and electronic equipment and/or another technical formulation (Bromkal 79-8DE) was also likely the source of octa- and nona-congeners in e-wastes. Comparison of the PBDE patterns in road and farmland soils implied that the PBDEs in farmland soils have been subject to complex environmental processes

  6. Distribuição regional e socioeconômica da disponibilidade domiciliar de alimentos no Brasil em 2008-2009 Distribución regional y socioeconómica de la disponibilidad domiciliaria de alimentos en Brasil, 2008-2009 Regional and socioeconomic distribution of household food availability in Brazil, in 2008-2009

    Directory of Open Access Journals (Sweden)

    Renata Bertazzi Levy

    2012-02-01

    Full Text Available OBJETIVO: Descrever a distribuição regional e socioeconômica da disponibilidade domiciliar de alimentos no Brasil. MÉTODOS: Estudo com dados secundários da Pesquisa de Orçamentos Familiares 2008-2009, realizada pelo Instituto Brasileiro de Geografia e Estatística sobre aquisições de alimentos e bebidas para consumo domiciliar. As quantidades de alimentos, registradas durante sete dias consecutivos nos 55.970 domicílios brasileiros amostrados, foram transformadas em calorias e nutrientes. Indicadores de qualidade da dieta foram construídos e analisados segundo estratos socioeconômicos e regionais da população brasileira. RESULTADOS: O teor protéico da disponibilidade alimentar mostrou-se adequado em todos os estratos regionais e econômicos. Em contrapartida, observou-se excesso de açúcares livres e de gorduras em todas as regiões, especialmente nas regiões Sul e Sudeste. A proporção de gorduras saturadas foi elevada no meio urbano e consistente com a maior participação de produtos de origem animal. A presença insuficiente de frutas, legumes e verduras foi comum em todas as regiões. Intensificação do teor de gorduras e diminuição do teor de carboidratos da dieta foram observadas com o aumento da renda. CONCLUSÕES: As características negativas da qualidade da dieta da população brasileira observadas ao final da primeira década do século XXI conferem alta prioridade para políticas públicas de promoção da alimentação saudável.OBJETIVO: Describir la distribución regional y socioeconómica de la disponibilidad domiciliaria de alimentos en Brasil. MÉTODOS: Estudio con datos secundarios de la Investigación de Presupuestos Familiares 2008-2009, realizada por el Instituto Brasileño de Geografía y Estadística sobre adquisiciones de alimentos y bebidas para consumo domiciliario. Las cantidades de alimentos, registradas durante siete días consecutivos en los 55.970 domicilios brasileños muestreados, fueron

  7. Avaliação do modelo regional eta utilizando as análises do CPTEC e NCEP Evaluation of the eta regional model using the analysis of CPTEC and NCEP

    Directory of Open Access Journals (Sweden)

    Rildo Gonçalves de Moura

    2010-03-01

    Full Text Available Os modelos numéricos de tempo são ferramentas essenciais para a previsão de curto e longo prazo, permitindo realizar a previsão com vários dias de antecedência. O conhecimento do desempenho dos modelos e dos erros sistemáticos a eles associados, é de suma importância, pois permite avaliar a capacidade dos mesmos em captar os processos físicos da atmosfera. Com intuito de melhorar a qualidade da previsão de tempo na América do Sul, disponibilizada no Centro de Previsão de Tempo e Estudos Climáticos (CPTEC, este trabalho avaliou as previsões de precipitação e pressão ao nível médio do mar para o prazo de até 120 horas, utilizando o erro médio (EM e a raiz do erro médio quadrático (REMQ no período de dezembro de 2007 a fevereiro de 2008. O modelo utilizado foi o ETA (40 km, com duas entradas distintas de dados, as análises do Physical-space Statistical Analysis System (PSAS (ETA-I e do National Centers for Environmental Predictions (NCEP (ETA-II. Os resultados mostraram, para ambas as análises, uma tendência de superestimativa (valores positivos do erro médio da precipitação sobre a Região Norte do Brasil, principalmente para 24 horas de previsão. Em relação à pressão ao nível médio do mar (PNMM foi possível verificar claramente que o ETA-I apresenta melhores resultados em comparação com o ETA-II, cujos valores de pressão se aproximaram bastante do observado, principalmente nas primeiras horas de integração.The numerical weather models are essential tools for predicting short and long term, allowing the prediction of weather conditions several days in advance. The knowledge of models performance and the systematic errors associated with them is extremely important because it allows to evaluate the ability to capture the physical processes of the atmosphere. In order to improve the quality of weather forecast in South America, available at Center for Weather Forecast and Climate Studies (CPTEC, this study

  8. Flexibilidade e crise do emprego industrial - sindicatos, regiões e novas ações empresariais Flexibility and the industrial employment crisis - unions, regions and new business actions

    Directory of Open Access Journals (Sweden)

    José Ricardo Ramalho

    2010-12-01

    Full Text Available Flexibilidade é uma palavra chave que sintetiza as mudanças decorrentes da reestruturação pelas quais passou a indústria nas últimas décadas. A redução do emprego industrial e suas consequências sociais e econômicas, são o foco da crítica social dirigida aos projetos baseados no padrão flexível, exigindo cada vez mais das empresas a elaboração de argumentos e ações para justificar e legitimar essa nova faceta do processo produtivo. O projeto AutoVision da montadora multinacional de veículos Volkswagen, aplicado em duas regiões - Wolfsburg, na Alemanha e ABC paulista, no Brasil, chama a atenção pelas características de uma intervenção social que veio acompanhada de um discurso mais elaborado de justificação. A hipótese a ser testada é a de que as iniciativas mais recentes das empresas globalizadas com base na flexibilidade, apontam para um protagonismo político na formulação de propostas com o objetivo de minorar os efeitos da redução do emprego na indústria e para a construção de uma retórica que naturaliza o emprego flexível. Teoricamente, esse caso permite também discutir os diferentes arranjos sociais com base na flexibilidade, que são criados regionalmente pelas empresas multinacionais e os modos como estas justificam suas ações¹.Flexibility is a key word that summarizes the changes that resulted from the restructuring of the industry in the recent decades. The decrease in industrial employment, as well as its social and economic consequences, is the focus of the social criticism directed at projects based on the flexible pattern, which require more and more actions from the part of the companies to justify and legitimize this new facet of the production process. The AutoVision project of the multinational automobile manufacturer Volkswagen - implemented in two regions: Wolfsburg, in Germany, and the ABC Region in the state of São Paulo, Brazil - presents the characteristics of a social

  9. The South American energy policies: regional problems and national logics; As politicas energeticas Sul-Americanas: problemas regionais e logicas nacionais

    Energy Technology Data Exchange (ETDEWEB)

    Le Prioux, Bruna [Centro de Pesquisa e Documentacao da America Latina (CREDAL) (France)

    2010-07-01

    sustainable development, interdependence and energy governance, to relate the national and international energy policies. Energy national policies are relevant factors to be considered when a regional integration is studied. In fact, energy advantages and deficiencies emerge in regional scenario, showing that the interdependences depend on national logics and strategies. In this sense, we consider that the effect of energy integration in South America is unsatisfying because national policies do not converge. The advantages of integration (i.e. commerce increase, ensuring supplies and reducing price volatility) are neutralized without this countries' coordination. (author)

  10. Persistent replication of a hepatitis C virus genotype 1b-based chimeric clone carrying E1, E2 and p6 regions from GB virus B in a New World monkey.

    Science.gov (United States)

    Suzuki, Saori; Mori, Ken-Ichi; Higashino, Atsunori; Iwasaki, Yuki; Yasutomi, Yasuhiro; Maki, Noboru; Akari, Hirofumi

    2016-01-01

    The development of effective hepatitis C virus (HCV) vaccines is essential for the prevention of further HCV dissemination, especially in developing countries. Therefore the aim of this study is to establish a feasible and immunocompetent surrogate animal model of HCV infection that will help in evaluation of the protective efficacy of newly developing HCV vaccine candidates. To circumvent the narrow host range of HCV, an HCV genotype 1b-based chimeric clone carrying E1, E2 and p6 regions from GB virus B (GBV-B), which is closely related to HCV, was generated. The chimera between HCV and GBV-B, named HCV/G, replicated more efficiently as compared with the HCV clone in primary marmoset hepatocytes. Furthermore, it was found that the chimera persistently replicated in a tamarin for more than 2 years after intrahepatic inoculation of the chimeric RNA. Although relatively low (chimeric RNA was found in the pellet fraction obtained by ultracentrifugation of the plasma at 73 weeks, indicating production of the chimeric virus. Our results will help establish a novel non-human primate model for HCV infection on the basis of the HCV/G chimera in the major framework of the HCV genome. © 2015 The Societies and John Wiley & Sons Australia, Ltd.

  11. Investigation of Regional Fractures and Cu Mineralization Relationships in the Khezrabad and Shahr-e-Babak Area: Using Fry and Fractal analysis

    Directory of Open Access Journals (Sweden)

    Alireza Zarasvandi

    2015-10-01

    Full Text Available Introduction Two main principal aspects for the genesis of porphyry copper deposits have been determined. The first genetic model concerns the petrologic and geochemical processes and the other relates the genesis to crustal deformation and geodynamic conditions (Kesler, 1997. Recent studies (e.g., Padilla Garza et al., 2001 show that the generation and emplacement of porphyry copper deposits may not only be dependent on magmatic and hydrothermal processes, but also that the regional and local tectonic setting plays an important role. Therefore in determining the suitable setting for emplacement of copper and other porphyry intrusions, determination of location of partial melting of the lower crust, generation of batholiths, and their volatile-rich derivative intrusions in the crust seems to be necessary (Carranza and Hale, 2002. Almost all porphyry copper deposits in Iran are located in the Urumieh-Dokhtar magmatic belt. These deposits show distinct spatial and temporal relationship with Miocene granodiorite plutonic rocks emplaced along strike slip faults (Mehrabi et al., 2005. Accordingly, the tectonic setting of ore deposits seem to be the most important factor for regional exploration of porphyry copper systems (Vearncombe and Vearncombe, 1999. There are several methods for analysis of distribution of ore deposits. In this research the role of structural control in the spatial distribution of porphyry deposits has been studied using Fry and Fractal methods. Here, the Fry method is used as a complementary method for Fractal analysis. Materials and methods Fry analysis is a self-adaptive method that is used for point objects. Fry analysis offers a visual approach to quantify the spatial trends in groups of point objects. Fry analysis can also be used to search for anisotropies in the distribution of point objects. More specifically it can be used to investigate whether a distribution of point objects occurs along linear trends, and whether

  12. Classificação e tendências climáticas em Lavras, MG Climatic classification and tendencies in Lavras region, MG

    Directory of Open Access Journals (Sweden)

    Antonio Augusto Aguilar Dantas

    2007-12-01

    Full Text Available Objetivou-se com este trabalho avaliar a tendência de dados climáticos nos últimos 14 anos, na região de Lavras, MG, comparando-os com aqueles da série histórica do período de 1961 a 1990. Foi utilizado o método do balanço hídrico de Thornthwaite & Mather (1955para os dados do período de 1961-1990 e para os dados recentemente observados de 1991-2004. O método do balanço hídrico de Thornthwaite considera a evapotranspiração potencial, a precipitação pluvial, o armazenamento de água no solo e seu subsequente uso. Este método também apresenta os períodos de excesso e deficiência hídrica, então utilizados no método de classificação climática de Thornthwaite para determinar os índices de umidade e de aridez. Os índices resultaram na fórmula climática de Thornthwaite que nesta comparação, mudou de B3 r B'3 a' para B2 r B'3 a' no período mais recente. A classificação climática de Köppen, também utilizada neste trabalho não apresentou diferenças para ambos os períodos, permanecendo Cwa.The purpose of this study was to evaluate the climatic data tendency in the last 14 years of monthly rainfall and temperatures in Lavras region, MG state , compared to those of the historical series of 1961-1990 period. The Thornthwaite's water balance method was employed for the climatological data of 1961-1990 and for the last observed data of 1991-2004. The Thornthwaite's & Mather´s water balance method considers the potential evapotranspiration, the rainfall, the storage of water in the ground and its subsequent use. This method also shows hidric excess and deficiency periods, then used on the Thornthwaite's climatic classification method to determine the moisture and aridity index of the climate. The index resulted on the Thornthwaite's climatic formula wich changed from B3 r B'3 a' to B2 r B'3 a' in the most recent reiod. The Köppen climatic classification method, also employed in this work, showed no changes, remaining

  13. Epidemiologia e diferenças regionais da retinopatia diabética em Pernambuco, Brasil Epidemiology and regional differences of diabetic retinopathy in Pernambuco, Brazil

    Directory of Open Access Journals (Sweden)

    Paulo Henrique Gonçalves Escarião

    2008-04-01

    Full Text Available OBJETIVOS: Avaliar os dados de freqüência e estadiamento da retinopatia diabética em Pernambuco, Brasil, comparando a região metropolitana com cidades do interior do estado. MÉTODOS: Os prontuários de 2.223 pacientes diabéticos (1.568 mulheres e 655 homens; idade média de 58,4 ± 12,0 anos; duração média do diabetes de 8,1 ± 6,3 anos, que fizeram parte de um programa de triagem para retinopatia diabética na Fundação Altino Ventura entre os meses de junho de 2004 e junho de 2005, foram revistos quanto à presença de retinopatia. Os pacientes foram divididos em dois grupos quanto à origem: grupo I, pacientes residentes em Recife e região metropolitana; grupo II, pacientes residentes no interior do estado de Pernambuco. RESULTADOS: No grupo I, 477 (24,2% pacientes apresentavam retinopatia diabética ao passo que no grupo II, 89 (39,4% pacientes (pPURPOSE: To evaluate the prevalence and severity of diabetic retinopathy among patients cared for in a screening program in Pernambuco, Brazil, comparing regional differences between urban and rural zones. METHODS: The charts of 2,223 diabetic patients (1,568 females and 655 males; mean age 59.3 ± 12.0 years; mean duration of diabetes 8.1 ± 6.3 years that took part in a screening program for diabetic retinopathy at Altino Ventura Foundation from June 2004 to June 2005 were reviewed for the presence of the disease. Patients were divided into two groups: group I, patients living in Recife and the metropolitan area; group II, patients living in the interior of Pernambuco state. RESULTS: In group I, 477 (24.2% patients had diabetic retinophathy, while in group II, 89 (39.4% patients (p<0.0001. The frequency of proliferative diabetic retinophathy, macular edema, vitreous hemorrhage and retinal detachment was higher in group II patients (p<0.05. CONCLUSIONS: Patients living in the interior of Pernambuco state have a higher incidence of diabetic retinophathy and the advanced forms than

  14. Mutational Analysis of the Hypervariable Region of Hepatitis E Virus Reveals Its Involvement in the Efficiency of Viral RNA Replication ▿

    Science.gov (United States)

    Pudupakam, R. S.; Kenney, Scott P.; Córdoba, Laura; Huang, Yao-Wei; Dryman, Barbara A.; LeRoith, Tanya; Pierson, F. William; Meng, Xiang-Jin

    2011-01-01

    The RNA genome of the hepatitis E virus (HEV) contains a hypervariable region (HVR) in ORF1 that tolerates small deletions with respect to infectivity. To further investigate the role of the HVR in HEV replication, we constructed a panel of mutants with overlapping deletions in the N-terminal, central, and C-terminal regions of the HVR by using a genotype 1 human HEV luciferase replicon and analyzed the effects of deletions on viral RNA replication in Huh7 cells. We found that the replication levels of the HVR deletion mutants were markedly reduced in Huh7 cells, suggesting a role of the HVR in viral replication efficiency. To further verify the results, we constructed HVR deletion mutants by using a genetically divergent, nonmammalian avian HEV, and similar effects on viral replication efficiency were observed when the avian HEV mutants were tested in LMH cells. Furthermore, the impact of complete HVR deletion on virus infectivity was tested in chickens, using an avian HEV mutant with a complete HVR deletion. Although the deletion mutant was still replication competent in LMH cells, the complete HVR deletion resulted in a loss of avian HEV infectivity in chickens. Since the HVR exhibits extensive variations in sequence and length among different HEV genotypes, we further examined the interchangeability of HVRs and demonstrated that HVR sequences are functionally exchangeable between HEV genotypes with regard to viral replication and infectivity in vitro, although genotype-specific HVR differences in replication efficiency were observed. The results showed that although the HVR tolerates small deletions with regard to infectivity, it may interact with viral and host factors to modulate the efficiency of HEV replication. PMID:21775444

  15. Gamma-Ray Emission of the Kes 73/1E 1841-045 Region Observed with the Fermi Large Area Telescope

    Energy Technology Data Exchange (ETDEWEB)

    Yeung, Paul K. H.; Kong, Albert K. H. [Institute of Astronomy and Department of Physics, National Tsing Hua University, Hsinchu, Taiwan (China); Tam, P. H. Thomas [Institute of Astronomy and Space Science, Sun Yat-Sen University, Guangzhou 510275 (China); Hui, C. Y. [Department of Astronomy and Space Science, Chungnam National University, Daejeon 305-764 (Korea, Republic of); Takata, Jumpei [School of physics, Huazhong University of Science and Technology, Wuhan 430074 (China); Cheng, K. S., E-mail: paul2012@connect.hku.hk, E-mail: akong@phys.nthu.edu.tw, E-mail: tanbxuan@mail.sysu.edu.cn [Department of Physics, University of Hong Kong, Pokfulam Road (Hong Kong)

    2017-03-01

    The supernova remnant (SNR) Kes 73 and/or the magnetar 1E 1841-045 at its center can deposit a large amount of energy to the surroundings and is potentially responsible for particle acceleration. Using the data taken with the Fermi Large Area Telescope (LAT), we confirmed the presence of an extended source whose centroid position is highly consistent with this magnetar/SNR pair. Its emission is intense from 100 MeV to >100 GeV. Its LAT spectrum can be decoupled into two components, which are respectively governed by two different mechanisms. According to the young age of this system, the magnetar is seemingly a necessary and sufficient source for the downward-curved spectrum below 10 GeV, as the observed <10 GeV flux is too high for the SNR to account for. On the other hand, the SNR is reasonably responsible for the hard spectrum above 10 GeV. Further studies of this region in the TeV regime is required so that we can perform physically meaningful comparisons of the >10 GeV spectrum and the TeV spectrum.

  16. Effect of Corm Density on Yield and Qualitative Traits of Saffron (Crocus sativus L. under Different Urea and Biological Fertilizers in Shahr-e-Rey Region

    Directory of Open Access Journals (Sweden)

    Alireza pazoki

    2017-07-01

    Full Text Available To study the effect of corm density on yield and qualitative traits of saffron (Crocus sativus L. under different biological and chemical nitrogen fertilizers, a factorial experiment based on completely randomized block design with 3 replications was done in 2014 at Shahr-e-Rey region (Ghomi Abad. The experimental factors were: corm density in 3 levels (60, 120 and 180 corm per square meter and biological and chemical nitrogen fertilizers in 4 levels (without fertilizer application, 150 kg.ha-1 of Urea, 5 L.ha-1 of Nitroxin and 75 kg.ha-1 of Urea +5 L.ha-1 of Nitroxin. The results indicated that the corm density affects number of daughter corm, fresh daughter corm weight, corm diameter, dry stigma and style weight, dry and fresh flower weight significantly. Mean comparisons also indicated that by increasing corm density from 6o to 180, saffron dry yield of saffron improved by 2.7 fold. However, increasing corm density reduced corm diameter, fresh corm daughter weight and their numbers per square meter. It can be concluded that nitroxin as an organic fertilizer, increases vegetative traits and saffron dry yield (stigma + style weight to 2.08 kg.ha-1 and highly improves in qualitative traits like Safranal, Picrocrocin, and Crocin. It can be also said that combined use of nitroxin and urea would be an alternative method to reduce application of urea.

  17. Photoelectron spectroscopy in a wide hν region from 6 eV to 8 keV with full momentum and spin resolution

    International Nuclear Information System (INIS)

    Suga, Shigemasa; Tusche, Christian

    2015-01-01

    Highlights: • Full two-dimensional angle resolved photoelectron spectroscopy (2D-ARPES). • Spin-resolved ARPES (SP-ARPES) with very high spin detection efficiency. • Aberration corrected double hemispherical deflection analyzers (HDAs). • Momentum microscopy (M.M.) with high energy and momentum resolutions. • Spin resolved momentum microscopy with capability of micro-nano region detection. - Abstract: High resolution photoelectron spectroscopy is recognized to be a very powerful approach to study surface and bulk electronic structures of various solids by employing different photon energies (hν). In particular, angle resolved photoelectron spectroscopy (ARPES) has progressed dramatically in the last few decades providing useful information on Fermi surface (FS) topology and band dispersions. The information of the electron spin is often decisive to fully understand the electronic properties of many material classes. However, spin-resolved studies by photoelectron spectroscopy were strongly hindered by the low detection efficiency of spin detectors. In the case of surface electronic structures, possible surface degradation with time is a serious problem to discuss intrinsic electronic effects. Therefore rather fast and high efficiency detection is required in the case of surface sensitive spin-resolved ARPES. Two-dimensional (2D) detection is nowadays widely employed in ARPES. In the use of a conventional hemispherical deflection analyzer (HDA), one direction on the 2D detector corresponds to the binding energy E_B and the other direction to the emission angle. The novel concept of momentum microscopy, however, directly provides 2D (k_x,k_y) maps of the photoemission intensities. The reciprocal space image directly represents the cross section through the valence band structure of the sample at a selected energy. By scanning E_B, very high resolution three-dimensional E_B(k_x,k_y) maps of the band-dispersion can be obtained with high efficiency. If

  18. Photoelectron spectroscopy in a wide hν region from 6 eV to 8 keV with full momentum and spin resolution

    Energy Technology Data Exchange (ETDEWEB)

    Suga, Shigemasa, E-mail: ssmsuga@gmail.com [Institute of Scientific and Industrial Research, Osaka University, Osaka (Japan); Max-Planck-Institute für Mikrostrukturphysik, Weinberg 2, 06120 Halle (Germany); Tusche, Christian [Max-Planck-Institute für Mikrostrukturphysik, Weinberg 2, 06120 Halle (Germany)

    2015-04-15

    Highlights: • Full two-dimensional angle resolved photoelectron spectroscopy (2D-ARPES). • Spin-resolved ARPES (SP-ARPES) with very high spin detection efficiency. • Aberration corrected double hemispherical deflection analyzers (HDAs). • Momentum microscopy (M.M.) with high energy and momentum resolutions. • Spin resolved momentum microscopy with capability of micro-nano region detection. - Abstract: High resolution photoelectron spectroscopy is recognized to be a very powerful approach to study surface and bulk electronic structures of various solids by employing different photon energies (hν). In particular, angle resolved photoelectron spectroscopy (ARPES) has progressed dramatically in the last few decades providing useful information on Fermi surface (FS) topology and band dispersions. The information of the electron spin is often decisive to fully understand the electronic properties of many material classes. However, spin-resolved studies by photoelectron spectroscopy were strongly hindered by the low detection efficiency of spin detectors. In the case of surface electronic structures, possible surface degradation with time is a serious problem to discuss intrinsic electronic effects. Therefore rather fast and high efficiency detection is required in the case of surface sensitive spin-resolved ARPES. Two-dimensional (2D) detection is nowadays widely employed in ARPES. In the use of a conventional hemispherical deflection analyzer (HDA), one direction on the 2D detector corresponds to the binding energy E{sub B} and the other direction to the emission angle. The novel concept of momentum microscopy, however, directly provides 2D (k{sub x},k{sub y}) maps of the photoemission intensities. The reciprocal space image directly represents the cross section through the valence band structure of the sample at a selected energy. By scanning E{sub B}, very high resolution three-dimensional E{sub B}(k{sub x},k{sub y}) maps of the band-dispersion can be

  19. AGRIEMAS project. Pilot project for promotion of environmental management system in the small and medium industries alimentary of region Abruzzo (Italy); Il progetto AGRIEMAS: un progetto pilota per la promozione di un sistema comunitario di ecogestione e audit nelle piccole e medie imprese del settore agroindustriale della regione Abruzzo

    Energy Technology Data Exchange (ETDEWEB)

    Luciani, R.; Andriola, L.; Brunetti, N. [ENEA Centro Ricerche Casaccia, S. Maria di Galeria, RM (Italy). Dipt. Ambiente; Vignati, S. [ENEA Centro Ricerche Casaccia, S. Maria di Galeria, RM (Italy). Dipt. Energia; Paci, S. [ENEA Centro Ricerche Casaccia, S. Maria di Galeria, RM (Italy). Dipt. Innovazione; Iacoboni, S.; Bonfitto, E. [ARSAA - Agenzia Regionale per i Servizi di Sviluppo Agricolo (Italy)

    1999-07-01

    The topic discussed in this report can be inserted within the context of case studies carried out by ENEA (National Agency for New Technology, Energy and the Environment) in the promotion of environmental management systems (EMAS - ISO14000). EMAS has a voluntary character; it intends to replace conflicting relations between control authority and firm with relations centred on a dialogue and action agreed upon by the parties, on the basis of impartial and reliable information. The report about AGRIEMAS pilot project illustrates the procedure for applying this regulation to the small and medium food industries of Region Abruzzo. [Italian] L'argomento del rappprto si inserisce nel contesto degli studi effettuati dall'ENEA nell'ambito della promozione dei sistemi di gestione ambientale (EMAS-ISO14000). Lo strumento EMAS, che ha carattere di volontarieta', intende sostituire un rapporto di tipo conflittuale fra autorita' di controllo e impresa con un rapporto centrato su un dialogo ed un'azione concertata tra le parti, sulle basi di un'informativa obiettiva ed affidabile. Il rapporto sul progetto pilota AGRIEMAS illustra il percorso per l'applicazione del regolamento EMAS nelle piccole e medie imprese del settore agroindustriale della regione Abruzzo.

  20. THE INFLUENCE OF E.U. INTEGRATION ON THE OVERALL DEVELOPMENT IN THE REGIONS NORTH-EAST OF ROMANIA, SUBCARPATHIA OF POLAND AND CENTRAL SLOVAKIA

    Directory of Open Access Journals (Sweden)

    Adrian Liviu SCUTARIU

    2013-06-01

    Full Text Available The existence of some notable development differences in EU at interstate and interregional level imposed the elaboration of a regional development policy aimed at reducing such disparities. The financial assistance provided by the EU is to help the underdeveloped regions. In this article we highlight the overall level of development and its evolution in Romania, Poland and Slovakia, at regional level, in the context of EU accession. Our attention will be focused on the North-East region of Romania, achieving a comparative analysis with two other similar regions from Poland and Slovakia: Subcarpathia and Central Slovakia, respectively.

  1. Source Estimation of Wintertime Soot Particles for an Urban Site Varanasi (25.30 N, 83.00 E) in Central Indo-Gangetic Plain Region

    Science.gov (United States)

    Singh, A. K.; Srivastava, M. K.; Dumka, U. C.; Singh, R. K.; Singh, R. S.; Tiwari, S.; Mehrotra, B. J.; Srivastava, A. K.

    2017-12-01

    Black carbon particles (BC: also called Soot) are formed by incomplete combustion of hydrocarbon based fuels (fossil fuel: coal, diesel, petrol, etc.) as well as due to burning of biomass and bio-fuels (wood, shrubs, dry leaves, etc.). Soot particles are warming agent to the atmosphere that gained wide attention in recent years due to their direct and indirect impacts on local, regional as well as global climate. The climatic effects due to soot are not well understood as indicated by large uncertainties in their climate forcing estimation, particularly in South and East Asian region, possibly due to unavailability of adequate database and information about the source. Measurement of wintertime BC mass concentrations for urban site in central IGP, `Varanasi' (25.30 N, 83.00 E), using a seven wavelength Aethalometer is reported in this work. Delta-C (=BC370 - BC880), which is an indicator of biomass/bio-fuels or residential coal burning is used to understand the source. Aethalometer based source apportionment model "Aethalometer model" was used to apportion the fossil fuel/traffic and wood/biomass burning mass concentration to the total BC mass. The preliminary results for representative month (January-2015) show that daily-average BC mass ranged from 4.47 to 20.70 μg m-3 (Average: 9.45 ± 4.15 μg m-3). The daily Absorption Ångström Exponent (AAE) and the ratio of BCff/BC and BCff/BCwb varied between 1.09 - 1.32, 0.67 - 0.92 and 2 - 40, respectively, due to the changes in BC emissions rates. The total BC, BC from fossil fuel (BCff) and BC from wood/biomass burning (BCwb) behaved in the remarkable diurnal pattern, behaving opposite to the mixing layer heights (MLHs). During daytime, MLHs are higher due to surface based solar warming and causes more volume of atmosphere for the BC dispersion. This phenomenon causes the surface measurement of lower BC mass during the daytime. The data is, however, still being processed for multi-year wintertime observations and the

  2. Características de identidade, qualidade e estabilidade da manteiga de garrafa. Parte II - estabilidade The stability of a Brazilian regional butter "Manteiga de Garrafa"

    Directory of Open Access Journals (Sweden)

    Carmem Lygia Burgos Ambrósio

    2003-12-01

    Full Text Available Com vistas a estabelecer o tempo de vida útil da manteiga de garrafa, duas marcas deste produto (A e B de ampla comercialização na cidade do Recife foram avaliadas quanto a estabilidade durante o armazenamento a 25ºC a intervalos de 0, 30, 60, 90 e 120 dias através da determinação do índice de peróxido, acidez, análise cromatográfica de ácidos graxos e análise sensorial. Segundo os resultados, a acidez apresentou uma elevação acentuada nos primeiros 30 dias de armazenamento estabilizando-se a seguir até 120 dias. O índice de peróxido aumentou ao longo do tempo sendo acompanhado pela intensificação do "flavour" de ranço para ambas amostras que a partir dos 90 dias de armazenamento foi referido como extremamente forte por 50% dos provadores. Quanto aos ácidos graxos, foi constatada diminuição do percentual do linoléico (18:2 na manteiga A embora nenhuma mudança tenha ocorrido no conteúdo de ácidos graxos trans para as duas manteigas. Os resultados demonstram que o tempo de armazenamento não exerce influência significativa e que a manteiga de garrafa apresenta uma curta vida-de-prateleira face a oxidação lipídica que a torna inadequada para consumo após 60 dias a partir da data de fabricação.Trying to establish the time of shelf-life of "manteiga de garrafa" (a kind of regional Brazilian butter, two brands of this product (A and B of wide commercialization in the city of Recife were analyzed as the stability during the storage at 25ºC to intervals of 0, 30, 60, 90 and 120 days through the determination of the peroxide value,% free fattty acid, fatty acid composition and sensorial evaluation. According to the results, acidity increased in the first 30 days of storage being stabilized up to 120 days, the peroxide value increased along the time being accompanied by the intensification of the "flavour" of rancidity for both samples that it was referred as extremely strong for 50% of the panelists starting from the

  3. Domains of apolipoprotein E contributing to triglyceride and cholesterol homeostasis in vivo. Carboxyl-terminal region 203-299 promotes hepatic very low density lipoprotein-triglyceride secretion

    NARCIS (Netherlands)

    Kypreos, K.E.; Dijk, K.W. van; Zee, A. van der; Havekes, L.M.; Zannis, V.I.

    2001-01-01

    Apolipoprotein (apo) E has been implicated in cholesterol and triglyceride homeostasis in humans. At physiological concentration apoE promotes efficient clearance of apoE-containing lipoprotein remnants. However, high apoE plasma levels correlate with high plasma triglyceride levels. We have used

  4. Climatology of mesopause region nocturnal temperature, zonal wind, and sodium density observed by sodium lidar over Hefei, China (32°N, 117°E)

    Science.gov (United States)

    Li, T.; Ban, C.; Fang, X.; Li, J.; Wu, Z.; Xiong, J.; Feng, W.; Plane, J. M. C.

    2017-12-01

    The University of Science and Technology of China narrowband sodium temperature/wind lidar, located in Hefei, China (32°N, 117°E), was installed in November 2011 and have made routine nighttime measurements since January 2012. We obtained 154 nights ( 1400 hours) of vertical profiles of temperature, sodium density, and zonal wind, and 83 nights ( 800 hours) of vertical flux of gravity wave (GW) zonal momentum in the mesopause region (80-105 km) during the period of 2012 to 2016. In temperature, it is likely that the diurnal tide dominates below 100 km in spring, while the semidiurnal tide dominates above 100 km throughout the year. A clear semiannual variation in temperature is revealed near 90 km, likely related to the tropical mesospheric semiannual oscillation (MSAO). The variability of sodium density is positively correlated with temperature, suggesting that in addition to dynamics, the chemistry may also play an important role in the formation of sodium atoms. The observed sodium peak density is 1000 cm-3 higher than that simulated by the model. In zonal wind, the diurnal tide dominates in both spring and fall, while semidiurnal tide dominates in winter. The observed semiannual variation in zonal wind near 90 km is out-of-phase with that in temperature, consistent with tropical MSAO. The GW zonal momentum flux is mostly westward in fall and winter, anti-correlated with eastward zonal wind. The annual mean flux averaged over 87-97 km is -0.3 m2/s2 (westward), anti-correlated with eastward zonal wind of 10 m/s. The comparisons of lidar results with those observed by satellite, nearby radar, and simulated by model show generally good agreements.

  5. Anestesia regional e trombocitopenia não pré-eclâmptica; hora de repensar o nível seguro de plaquetas Anestesia regional y trombocitopenia no preclámptica; es hora de pensar de nuevo sobre el nivel seguro de plaquetas Regional anesthesia and non-preeclamptic thrombocytopenia: time to re-think the safe platelet count

    Directory of Open Access Journals (Sweden)

    Motoshi Tanaka

    2009-04-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Apesar de a anestesia regional ser amplamente utilizada no controle da dor em obstetrícia, seu uso pode não ser apropriado nas pacientes com trombocitopenia por causa do risco de hematoma no neuroeixo. Não existem fortes evidências sugerindo número mínimo de plaquetas necessário para garantir a segurança na realização da anestesia regional. O objetivo deste estudo foi rever a segurança da anestesia regional em pacientes com trombocitopenia não pré-eclâmptica na instituição durante período de cinco anos. MÉTODO: Foi realizada revisão retrospectiva dos prontuários médicos de todas as pacientes obstétricas não pré-eclâmpticas cujo parto foi realizado na instituição entre abril de 2001 e março de 2006 e que apresentaram contagem de plaquetas JUSTIFICATIVA Y OBJETIVOS: A pesar de que la anestesia regional esté siendo muy utilizada en el control del dolor en obstetricia, su uso puede no ser muy apropiado en las pacientes con trombocitopenia, debido al riesgo de hematoma en el neuro eje. No existen fuertes evidencias que sugieran un número mínimo de plaquetas necesario para garantizar la seguridad en la realización de la anestesia regional. El objetivo de este estudio fue analizar la seguridad de la anestesia regional en pacientes con trombocitopenia no preeclámptica en la institución durante un período de cinco años. MÉTODO: Fue realizada revisión retrospectiva de las historias clínicas médicas de todas las pacientes obstétricas no preeclámpticas cuyo parto fue realizado en la institución entre abril de 2001 y marzo de 2006 y que presentaron BACKGROUND AND OBJECTIVES: Although regional anesthesia is widely used for pain control in obstetrics, it may not be appropriate for patients with thrombocytopenia due to the risk of neuraxial hematoma. There is no strong evidence to suggest the minimum platelet count that is necessary to ensure the safe practice of regional anesthesia. The

  6. Regionální disparity v míře nezaměstnanosti na příkladu ČR

    OpenAIRE

    Nezbeda, Jaroslav

    2015-01-01

    The thesis analyzes factors, which affect regional unemployment rate in districts of the Czech Republic. It analyzes panel data of fourteen districts of the Czech Republic from years 2000-2012. It works with method of fixed effects. Next thesis covers two alternativ models, first model analyzes impact of the economic crisis between years 2000-2012 on determinants of regional unemployment rate. Second alternativ model compares factors affecting regional unemployment rate in districts of the Sl...

  7. Analysis of economic convergence within Chiapas municipalities, regions and apparent inconsistencies Análisis de convergencia económica en el interior de Chiapas: municipios, regiones e inconsistencias aparentes

    Directory of Open Access Journals (Sweden)

    Óscar PELÁEZ HERREROS

    2012-06-01

    Full Text Available The data of annual per capita income estimated by the United Nations Development Programme (UNDP for the municipal human development index in Mexico shows that, in Chiapas, during the period 2000-2005, there was a strong convergence at the municipal level while there was no regional convergence. To explain this apparent inconsistency, the article «Regression towards mediocrity in hereditary stature», published by Galton in 1886, is examined, concluding that the clustering level of the data (municipal or regional determines the convergence analysis results, because the grouping of municipalities in regions causes loss of information that can generate phenomena of «regression towards the mean» or just the opposite, as is the case. In Chiapas, the municipal convergence would have led to convergence within the regions but not between regions.A partir de los datos de ingreso per cápita anual estimados por el Programa de las Naciones Unidas para el Desarrollo (PNUD en la elaboración del índice de desarrollo humano municipal en México, se comprueba que, en el interior de Chiapas durante el periodo 2000- 2005, se dio un proceso de fuerte convergencia a nivel municipal al tiempo que no hubo convergencia regional. Para explicar esta aparente inconsistencia, se reexamina el artículo «Regression towards mediocrity in hereditary stature» publicado por Galton en 1886, concluyendo que el nivel de agrupación de los datos (municipal o regional condiciona los resultados del análisis de convergencia, ya que la agrupación de los municipios en regiones origina pérdidas de información que pueden generar fenómenos de «regresión hacia la media» o justo lo contrario, como es el caso. En Chiapas, la convergencia municipal habría dado lugar a la convergencia dentro de las regiones, pero no entre regiones.

  8. Usability evaluation of an eLearning course presenting a regional destination: the case of “Ticino Switzerland Travel Specialist”

    OpenAIRE

    Kalbaska, Nadzeya; Jovic, Angelina; Cantoni, Lorenzo

    2013-01-01

    In recent years Destination Management Organizations (DMOs) have started to offer eLearning courses, which train travel agents and tour operators to promote better tourism destinations. eLearning courses increase marketing activities of a DMO also they meet the needs of travel agents, who are in search of new unique selling points in the threatening context of eTourism disintermediation. Nevertheless, the user-friendly appearance of these eLearning courses and their easiness of use are stil...

  9. Capacidade de inovação regional: o papel de instituições e empresas de base tecnológica em Juiz de Fora Regional innovation capacity: the role of institutions and firms in Juiz de Fora

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    Eduardo Gonçalves

    2002-01-01

    Full Text Available The starting point of this paper is the interrelation between learning, innovation, regional and local development in the 'Knowledge or Learning Economy'. Along with the traditional economic factors that have been considered in the literature on regional development, other factors such as trust, co-operation, innovative networks, institutions and other elements that are immaterial produce the regional development in the context of the 'Learning Economy'. The main aim of this paper is to investigate the attempts to build a collective and regional learning process by innovative, technology based, small sized enterprises, together with other institutions in the city of Juiz de Fora. It highlights the local institutional environment and the characteristics of some information and knowledge intensive firms, supported by the Regional Center for Innovation and Technology Transference at the Federal University of Juiz de Fora. Moreover, special emphasis is given to some evidence about co-operation, innovative networks and external sources of information that are used to innovate.

  10. Reframing political violence and mental health outcomes: outlining a research and action agenda for Latin America and the Caribbean region Reformulando a violência política e efeitos na saúde mental: esboçando uma agenda de pesquisa e ação para a América Latina e região do Caribe

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    Duncan Pedersen

    2006-06-01

    Full Text Available In recent decades, the number of people exposed to traumatic events has significantly increased as various forms of violence, including war and political upheaval, engulf civilian populations worldwide. In spite of widespread armed conflict, guerrilla warfare and political violence in the Latin American and Caribbean region, insufficient attention had been paid in assessing the medium and long-term psychological impact and additional burden of disease, death, and disability caused by violence and wars amongst civilian populations. Following a review of the literature, a few central questions are raised: What is the short, medium and long-term health impact of extreme and sustained forms of violence in a given population? How political violence is linked to poor mental health outcomes at the individual and collective levels? Are trauma-related disorders, universal outcomes of extreme and sustained violence? These questions lead us to reframe the analysis of political violence and mental health outcomes, and reexamine the notions of trauma, after which a research and action agenda for the region is outlined. In the concluding sections, some basic principles that may prove useful when designing psychosocial interventions in post-conflict situations are reviewed.Em décadas recentes, o número de pessoas expostas a eventos traumáticos tem aumentado significativamente, bem como formas de violência como guerras e revoluções políticas, que subjugam populações civis em todo o mundo. Apesar da dispersão dos conflitos armados, guerrilhas e violência política na América Latina e Caribe, atenção insuficiente tem sido dada para avaliar o impacto psicológico a médio e longo prazo e o peso das doenças, mortes, e invalidez provocadas pela violência e guerra contra populações civis. Algumas perguntas centrais são levantadas, a partir de revisão da literatura: qual o impacto na saúde da população, a curto, médio e longo prazo, ao

  11. Reformulando a violência política e efeitos na saúde mental: esboçando uma agenda de pesquisa e ação para a América Latina e região do Caribe Reframing political violence and mental health outcomes: outlining a research and action agenda for Latin America and the Caribbean region

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    Duncan Pedersen

    2006-01-01

    Full Text Available Em décadas recentes, o número de pessoas expostas a eventos traumáticos tem aumentado significativamente, bem como formas de violência como guerras e revoluções políticas, que subjugam populações civis em todo o mundo. Apesar da disseminação dos conflitos armados, guerrilhas e violência política na América Latina e Caribe, atenção insuficiente tem sido dada para avaliar o impacto psicológico a médio e longo prazo e o peso das doenças, mortes, e invalidez provocadas pela violência e guerra contra populações civis. Algumas perguntas centrais são levantadas, a partir de revisão da literatura: qual o impacto na saúde da população, a curto, médio e longo prazo, por vivenciar violências extremas e continuadas? Como a violência política se relaciona com pobre saúde mental individual e coletiva? As desordens relacionadas aos traumas são conseqüências universais da violência extrema e continuada? Essas perguntas nos levam a reformular a análise da violência política e de suas conseqüências sobre a saúde mental e a reexaminar as noções de trauma e a agenda da pesquisa e ação para a região. Ao fim, são apresentados alguns princípios básicos que podem ser úteis ao se projetar intervenções psicosociais.In recent decades, the number of people exposed to traumatic events has significantly increased as various forms of violence, including war and political upheaval, engulf civilian populations worldwide. In spite of widespread armed conflict, guerrilla warfare and political violence in the Latin American and Caribbean region, insufficient attention had been paid in assessing the medium and long-term psychological impact and additional burden of disease, death, and disability caused by violence and wars amongst civilian populations. Following a review of the literature, a few central questions are raised: What is the short, medium and long-term health impact of extreme and sustained forms of violence in a

  12. Prevalência e fatores associados a sobrepeso e obesidade em adolescentes de 15 a 19 anos das regiões Nordeste e Sudeste do Brasil,1996 a 1997 Prevalence of overweight and obesity and associated factors among adolescents in the Northeast and Southeast regions of Brazil, 1996 to 1997

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    Vera Cristina Magalhães

    2003-01-01

    Full Text Available O estudo objetivou avaliar a prevalência de sobrepeso e obesidade (S/O e fatores associados, em adolescentes de duas regiões do Brasil, segundo o Índice de Massa Corporal. Baseou-se nos dados da Pesquisa sobre Padrões de Vida, inquérito domiciliar realizado pelo IBGE (1998a, entre 1996 e 1997, nas regiões Nordeste e Sudeste do Brasil e incluiu 1.027 e 854 adolescentes de 15 a 19 anos, respectivamente. A análise estatística considerou os fatores de expansão e o desenho da amostra. A prevalência de S/O foi de 8,45% no Nordeste e 11,53% no Sudeste. No Nordeste, observou-se maior risco de S/O para meninas (RP = 3,00, na área urbana (RP = 3,21 e na rural (RP = 2,27. Observou-se menor risco de S/O para meninas do Sudeste (RP = 0,58, também na área urbana (RP = 0,51, mas não na rural (RP = 1,86. O aumento da renda per capita domiciliar mensal se associou ao risco de S/O em meninos do Nordeste (chi2 de tendência linear: p = 0,002 e Sudeste (chi2 de tendência linear: p = 0,006. Concluiu-se a necessidade de programas de prevenção a S/O que incluam reeducação alimentar e estímulo à atividade física, considerando as diferenças sócio-econômicas e culturais regionais da população alvo.The purpose of this study was to assess the prevalence and factors associated with overweight and obesity (OW/O among Brazilian adolescents, based on the Living Standards Survey conducted in 1996 and 1997 (IBGE, 1998a. The sample included 1,027 and 854 adolescents aged 15 to 19 years from the Northeast and Southeast regions, respectively. Body Mass Index (w/h2 was calculated. Statistical analysis considered expansion factors and sample design. Prevalence of OW/O was 8.45% in the Northeast and 11.53% in the Southeast. In the Northeast there was a higher risk of OW/O for girls (PR = 3.00, with the same situation in both urban (PR = 3.21 and rural areas (PR = 2.27. In the Southeast, the risk of OW/O was lower among girls (PR = 0.58. The same situation

  13. Povos indígenas fronteiriços da Venezuela: aspectos da segurança e o desenvolvimento de integração regional

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    Jenny Gonzáles Muñoz

    2017-08-01

    Full Text Available Este artigo tem como objetivo geral analisar os fatores de risco e da força dos povos indígenas na fronteira da Venezuela, em relação à vulnerabilidade dessas áreas e seu impacto sobre a segurança da nação, este estudo concluído em 2016, leva em conta a diversidade étnica, o multiculturalismo e a convivência cívica na horizontalidade, onde as culturas de conhecimento e existência do "outro" desempenha um papel significativo em áreas de vida, especialmente quando se fala de "desenvolvimento" e suas implicações sociais subseqüentes. No século XX e XXI a situação dos povos indígenas que vivem em áreas de fronteira da Venezuela (Colômbia, Brasil, Guiana com fatores como a coexistência com forças armadas nacionais e estrangeiras, e outros setores não indígenas, combinado com a força alinhando a sua presença no assentamento da fronteira e do Desenvolvimento Integral da Nação. Metodologicamente, uma abordagem transdisciplinar está, portanto, ligada cultural, social e militarmente, com base em uma perspectiva holística da abordagem da legislação.

  14. A PRODUÇÃO VITIVINÍCOLA DA SERRA GAÚCHA – BRASIL E DE MENDONZA - ARGENTINA: UMA ANÁLISE COMPARATIVA A LUZ DAS TEORIAS DE DESENVOLVIMENTO REGIONAL

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    Cilane Vieira

    2008-08-01

    Full Text Available A importância da localização das atividades produtivas e da população, bem como dos seus determinantes, tem recebido atenção crescente na literatura nas últimas décadas e, com isso, tornado ainda mais evidente a necessidade de um melhor entendimento da complexidade envolvida nesse debate. Desde os modelos pioneiros de Von Thunen e Weber até os mais recentes desdobramentos da Nova Geografia Econômica (NGE, muitos elementos tais como localização da mão-de-obra, minimização de custos, proximidade do mercado consumidor, etc. foram considerados “fundamentais” pelos teóricos envolvidos neste debate para explicar a localização das atividades e o desenvolvimento das regiões. Este estudo perseguiu dois objetivos principais. O primeiro deles foi discutir a aplicabilidade/adaptabilidade das teorias de desenvolvimento regional para explicar a realidade em foco. O segundo buscou analisar, comparativamente, as regiões escolhidas identificando os elementos determinantes que caracterizam o desenvolvimento das mesmas. Os resultados mostram que os modelos acompanharam a complexidade dos mercados de cada época e, portanto, servem como instrumento para analisar e entender o contexto de uma região em um dado momento e nortear as políticas públicas que visem o desenvolvimento regional.

  15. Governança para a territorialidade e sustentabilidade: a construção do senso de regionalidade Governance towards territorial sustainable development: building a sense of regionality

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    Luciano Marcelo França

    2012-12-01

    Full Text Available No atual contexto das abordagens multiescalares, espacial e setorial das propostas de gestão pública, a regionalidade vêm ganhando destaque na medida em que a complexidade administrativa aumenta por conta da modificação das demandas sociais. Neste contexto, torna-se desafiadora a correlação entre governança, territorialidade e sustentabilidade. Inspirados neste contexto e a partir de uma pesquisa bibliográfica sobre os temas, realizou-se uma análise das relações políticas entre os integrantes do Conselho de Desenvolvimento da Secretaria de Desenvolvimento Regional (SDR de Blumenau. A pesquisa é descritiva, baseada em entrevistas semiestruturadas realizadas com membros do conselho da SDR no período de sua criação, 2003, até 2008. O modo como a SDR está estruturada, bem como a forma que seus municípios enxergam a si mesmos e aos outros neste contexto, produzem propostas de intervenção e prática institucional que assimilam demandas individuais e coletivas, mas também transformam em certo grau a organização política e econômica da região de sua abrangência. Como uma política que se declara em busca da descentralização, inicia-se em Santa Catarina a experimentação de uma dinâmica desenvolvimentista que busca a homogeneidade e o nivelamento da região em questão esta lógica é perceptível na medida em que os municípios pertencentes a uma regional assumem seus problemas, sobretudo de educação e saúde, por tratarem de atividades de natureza pública, e aqueles dos municípios vizinhos com potencialidades e representatividades políticas diversas. Isto foi explorado a partir das ideias de sustentabilidade política e administrativa que conduza a um desenvolvimento inclusivo e harmonizador propiciado pelas instâncias formalizadas e legitimadas pela institucionalidade que os suporta.The goal of this article is to present an analysis of the politic relations between the participants of the Secretary of Regional

  16. Desarrollo de la Hematología en Cuba. Perspectivas y posibilidades de colaboración regional e internacional: Perspectives and possibilities of regional and international cooperation Development of the Hematology in Cuba

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    José M. Ballester-Santovenia

    2011-03-01

    Full Text Available Desde la fundación en 1966, del Instituto de Hematología e Inmunología (IHI, centro rector de la especialidad en Cuba, se ha trabajado intensamente en la búsqueda y aplicación de los protocolos de tratamiento más actuales y la introducción de innovaciones tecnológicas para el diagnóstico y tratamiento de pacientes con hemopatías, lo que ha permitido alcanzar niveles de curación similares a los de países desarrollados, en enfermedades como la leucemia linfoide aguda en niños, y se ha logrado la aplicación de estos protocolos en todos los servicios de hematología del país. Con la atención integral a los pacientes hemofílicos y con anemia drepanocítica, se ha elevado su expectativa de vida con una calidad de vida superior. Se han formado especialistas para todo el Sistema Nacional de Salud (SNS, así como enfermeras, técnicos y otros profesionales vinculados con la especialidad, que también realizan colaboración en diversos países. El nivel alcanzado ha permitido la contribución, de manera relevante, en el desarrollo del trasplante de médula ósea, y en el campo de la Medicina Regenerativa se ha logrado introducir el autotrasplante con células madre en varias enfermedades, en lo que ya participan diferentes centros del país. La seguridad de la sangre y la garantía de su calidad ha sido objetivo determinante en la Medicina Transfusional, que es vital para todas las ramas de las ciencias médicas. Esta labor y los resultados exitosos obtenidos, han posibilitado la integración de una red nacional de servicios de hematología que contribuye decisivamente al fortalecimiento del SNS y es ejemplo destacado de los logros de la medicina revolucionaria. Esta experiencia abre posibilidades para incrementar la colaboración internacional y fundamentalmente, para la integración con otros países, principalmente de nuestra región, que contribuya a optimizar los niveles de salud y mejorar la calidad de vida de nuestros pueblos

  17. A Inovação Tecnológica na Sociedade do Conhecimento e o Papel Social da Embrapa no Desenvolvimento Regional

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    Fabiana Cunha Viana Leonelli

    2011-06-01

    Full Text Available Em um ambiente caracterizado, cada vez mais, pelo acesso a informação e, principalmente, pela transversalidade do conhecimento, faz-se necessário compreender como a inovação tecnológica pode ter reflexos tangíveis e intangíveis na organização.A inovação pode ser entendida como a capacidade que a empresa tem em gerar novas idéias, identificar oportunidades e transformar esforços em produtos comercializáveis, buscando vincular a inovação com a geração de valor para a empresa, quase sempre, financeiro. No caso da Empresa Brasileira de Pesquisa Agropecuária – Embrapa, a geração de valor advinda das inovações se expressa não apenas pela arrecadação de royalties, mas, sobretudo, pelo avanço do conhecimento e pelos benefícios sociais e ambientais que uma tecnologia pode gerar para quem a adota, para o entorno e para a sociedade. Neste sentido, pensar a inovação tecnológica nesta dimensão é complexo e envolve elementos que extrapolam os fatores tradicionais de produção. A capacidade inovadora é formada por uma sinergia entre cultura organizacional, processos internos e relacionamentos inter-organizacionais.

  18. Leptomeningite e tumor da região optoquiasmática Meningitis and tumor of the opto-chiasmatic region. Report of two cases

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    J. A. Gonçalves da Silva

    1967-03-01

    Full Text Available São registrados dois casos de tumores situados no assoalho da fossa craniana média (carcinoma sólido da hipófise e craniofaringeoma acompanhados de leptomeningite de etiologia não determinada. Especialmente no segundo caso esta se caracterizava pela ocorrência de repetidos surtos de exacerbação. Em ambos o diagnóstico inicial foi de leptomeningite, tendo sido o insucesso das medidas terapêuticas adotadas que levou a estudos radiológicos, na tentativa de evidenciar focos que pudessem estar mantendo a infecção. Em ambos os casos o exame radiológico forneceu dados que permitiram orientar o diagnóstico de tumor do assoalho da fossa craniana média. As condições clínicas, no entanto, impediram que fossem adotadas em tempo útil medidas terapêuticas que visassem diretamente o tumor, vindo os pacientes a falecer. A possibilidade da ocorrência de meningites em tumores dessa região é discutida, bem como a natureza séptica ou asséptica da reação inflamatória. Os casos apresentados permitem concluir que, em processos meningíticos de evolução longa, acompanhados de surtos de agudização, nos quais nem mesmo durante os surtos agudos é encontrado o agente etiológico no LCR, a possibilidade da ocorrência de tumores do assoalho da fossa média do crânio deve ser estudada. O estudo deve ser feito precocemente, para permitir a adoção de medidas terapêuticas adequadas, visando diretamente o tumor, em tempo hábil, na tentativa de evitar que os surtos meningíticos venham a comprometer a vida do paciente.A study was made of a patient with carcinoma of the hypophisis which invaded the sphenoid bone and made protrusion under the nasopharyngeal mucosa, and that of a patient with craniopharyngeoma. The patients had no symptoms proper to the tumors but presented several episodes of meningitis. The presence of the tumor, in both cases, was evidenced lately, when the failure of the antibiotic therapy became patent leading to the

  19. Seroprevalence for hepatitis E virus (HEV infection among volunteer blood donors of the Regional Blood Bank of Londrina, State of Paraná , Brazil Soroprevalência da infecção pelo virus da hepatite E (VHE em candidatos a doadores de sangue voluntários do Hemocentro Regional de Londrina, Londrina, Estado do Paraná, Brasil

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    André Luiz Bortoliero

    2006-04-01

    Full Text Available A cross-sectional study was carried out among 996 volunteer blood donors enrolled from May 1999 to December 1999 to determine the seroprevalence of hepatitis E virus (HEV infection among volunteer blood donors of the Regional Blood Bank of Londrina, State of Paraná, Brazil, and to evaluate whether the rate of seroprevalence of IgG anti-HEV antibodies is associated with sociodemographic variables and with seropositivity for hepatitis A virus (HAV infection. All participants answered the questionnaire regarding the sociodemographic characterisitcs. Serum samples were tested for IgG antibodies to HEV (anti-HEV by an enzyme linked immunoassay (ELISA. All serum samples positive for anti-HEV IgG and 237 serum samples negative for anti-HEV were also assayed for IgG anti-HAV antibodies by ELISA. Anti-HEV IgG was confirmed in 23/996 samples, resulting in a seroprevalence of 2.3% for HEV infection, similar to previous results obtained in developed countries. No significant association was found between the presence of anti-HEV IgG antibodies and the sociodemographic variables including gender, age, educational level, rural or urban areas, source of water, and sewer system (p > 0.05. Also, no association with seropositivity for anti-HAV IgG antibodies was observed (p > 0.05. Although this study revealed a low seroprevalence of HEV infection in the population evaluated, the results showed that this virus is circulating among the population from Londrina, South Brazil, and point out the need of further studies to define the clinical and epidemiological importance of HEV infection and to identify additional risk factors involved in the epidemiology and pathogenesis of this infection in this population.Os objetivos do estudo foram determinar a soroprevalência da infecção pelo vírus da hepatite E (VHE em candidatos a doadores de sangue voluntários do Hemocentro Regional de Londrina, Paraná, e avaliar se essa soroprevalência está associada com vari

  20. Capacidade de inovação regional: o papel de instituições e empresas de base tecnológica em Juiz de Fora

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    Eduardo Gonçalves

    2009-05-01

    Full Text Available The starting point of this paper is the interrelation between learning, innovation, regional and local development in the “Knowledge or Learning Economy”. Along with the traditional economic factors that have been considered in the literature on regional development, other factors such as trust, co-operation, innovative networks, institutions and other elements that are immaterial produce the regional development in the context of the “Learning Economy”. The main aim of this paper is to investigate the attempts to build a collective and regional learning process by innovative, technology based, small sized enterprises, together with other institutions in the city of Juiz de Fora. It highlights the local institutional environment and the characteristics of some information and knowledge intensive firms, supported by the Regional Center for Innovation and Technology Transference at the Federal University of Juiz de Fora. Moreover, special emphasis is given to some evidence about co-operation, innovative networks and external sources of information that are used to innovate.

  1. Uso de combustíveis e emissões de CO2 no Brasil: um modelo inter-regional de insumo-produto

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    Emerson Martins Hilgemberg

    2006-04-01

    Full Text Available This study quantifies CO2 emissions caused by consumption of natural gas, alcohol and petroleum derivatives for six Brazilian regions, and evaluates the impact of possible policies for emission control. The connection between the level of activity and CO2 emissions for each energy input is presented for the six regions considered, detailing the portion of the total emissions caused by final demand, inter-industry consumption and household consumption. The model was also used to make simulations in order to evaluate the economic effects of a hypothetical restriction on emissions and the effects that an emission tax would cause.

  2. Bupivacaína racêmica, levobupivacaína e ropivacaína em anestesia loco-regional para oftalmologia: um estudo comparativo Racemic bupivacaine, levobupi vacaine and ropivacaine in regional anesthesia for ophtalmology: a comparative study

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    Edno Magalhães

    2004-04-01

    Full Text Available OBJETIVO: A bupivacaína racêmica, utilizada largamente em anestesia peribulbar devido à boa qualidade de bloqueio motor, apresenta menor margem de segurança para cardiotoxicidade em relação a ropivacaína e bupivacaína levógira. O objetivo deste estudo foi comparar o grau de bloqueio motor e alteração da pressão intra-ocular (PIO em anestesia peribulbar produzida pela bupivacaína racêmica, levobupivacaína e ropivacaína. MÉTODOS: Noventa e sete pacientes, estado físico I e II da classificação da Sociedade Americana de Anestesiologistas, submetidos a anestesia peribulbar, foram divididos em três grupos: grupo A-(n=16 bupivacaína racêmica 0,75% com adrenalina 1:200.000; grupo B -(n=16 bupivacaína levógira 0,75% com adrenalina 1:200.000; grupo C -(n=15 ropivacaína 0,75%. Utilizou-se 7ml da solução anestésica com 280 UI de hialuronidase, em punção única no rebordo orbital inferior. Foram registrados a PIO e grau de bloqueio motor 5 minutos antes da punção e 1, 2, 3, 4, 5 e 10 minutos após a punção. O bloqueio motor foi avaliado pela escala de Nicoll. Para a análise estatística, foram utilizados os testes de Wilcoxon, análise de freqüência simples e t de Student. Foi considerado significativo pBACKGROUND AND OBJECTIVE: Racemic bupivacaine, used in peribulbar anesthesia owing to its high potential to promote motor blockade, presents a smaller safety margin for cardiotoxicity in relation to ropivacaine and levobupivacaine. The objective of this study was to compare the degree of motor blockade and alteration of intraocular pressure (IOP produced by racemic bupivacaine, levobupivacaine and ropivacaine in peribulbar block. METHOD: Ninety seven patients, ASA physical status I and II, submitted to peribulbar anesthesia, were randomly allocated into three groups: group A-(n=16 receiving racemic bupivacaine 0.75% with epinephrine 1:200.000; group B -(n=16 levobupivacaine 0.75% with epinephrine 1:200.000; group C -(n=15

  3. Serviço público e regiões: reflexões em torno da informação de âmbito regional

    OpenAIRE

    Ascensão, Patrícia

    2017-01-01

    A reflexão sobre o serviço público de rádio e de televisão insere-se num campo de discussão muito mais extenso e que se inter-relaciona com outros domínios e contextos da sociedade contemporânea. São vários os autores que consideram que o serviço público está em crise e que é crucial encontrar soluções que possam contrariar este cenário, fortemente influenciado pelas leis do mercado bem como pelas políticas definidas para o setor dos media, quer a nível nacional quer a nível europeu. Daí que ...

  4. Microrregião Pajeú: economia, clima e desenvolvimento da agricultura através de modelo digital do terreno | Micro region Pajeú: economy, climate and development of agriculture through model digital terrain

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    Nina Iris Verslype

    2016-04-01

    precipitation, population, Human Development Index and Gross Domestic Product, in order to view the development of the region studied. Municipalities analyzed were: Afogados da Ingazeira, Brejinho, Calumbi, Carnaíba, Flores, Iguaraci, Ingazeira, Itapetim, Quixaba, Santa Cruz da Baixa Verde, Santa Terezinha, São José do Egito, Serra Talhada, Solidão, Tabira, Triunfo e Tuparetama. With climate analysis was possible to realize that the micro region has presents a hot climate with long periods of drought and irregular precipitation alternating between the months of January and May, yet the local economy stands out in livestock is the most developed activity of the Brazilian wilderness

  5. Additions To The Lichen Biota Of SE Siberia: Records From The Stanovoye Nagor’e Highlands (Trans-Baikal Region, Russia

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    Chesnokov Sergey

    2015-12-01

    Full Text Available This paper reports 120 species of lichens and one lichenicolous fungus from the Stanovoye Nagor’e Highlands in southeastern Siberia, including 64 species new for the area. Some of the newly recorded species are extremely rare in Russia [e.g., Bryonora curvescens (Mudd Poelt, Gyalideopsis alnicola Noble & Vězda and Pilophorus strumaticus Nyl. ex Cromb.]. The distribution and habitat preferences of several rare species are briefly discussed.

  6. Epidemiology of Extended-Spectrum beta-Lactamase-Producing E-coli and Vancomycin-Resistant Enterococci in the Northern Dutch-German Cross-Border Region

    NARCIS (Netherlands)

    Zhou, Xuewei; Garcia-Cobos, Silvia; Ruijs, Gijs J. H. M.; Kampinga, Greetje A.; Arends, Jan P.; Borst, Dirk M.; Moller, Lieke V.; Holman, Nicole D.; Schuurs, Theo A.; van Coppenraet, Lesla E. Bruijnesteijn; Weel, Jan F.; van Zeijl, Jan H.; Koeck, Robin; Rossen, John W. A.; Friedrich, Alexander W.

    2017-01-01

    Objectives: To reveal the prevalence and epidemiology of extended-spectrum β-lactamase (ESBL)- and/or plasmid AmpC (pAmpC)- and carbapenemase (CP) producing Enterobacteriaceae and vancomycin-resistant enterococci (VRE) across the Northern Dutch-German border region. Methods: A point-prevalence study

  7. Navegando pelas ondas do desenvolvimento: Baixada Santista em busca de um porto seguro - desenvolvimento, metropolização e os (des) compassos da gestão urbano-regional em múltiplos olhares sociais

    OpenAIRE

    Viana, Mônica Antonia

    2010-01-01

    Este trabalho é uma reflexão sobre o fenômeno urbano da metropolização das cidades contemporâneas no contexto do modo de produção capitalista, em especial no estágio atual, diante dos impactos da globalização econômica e da reestruturação produtiva do capital. Assim, busca-se analisar de forma crítica as diferentes dimensões, (inter)conexões e contradições existentes entre Desenvolvimento, Metropolização e Planejamento e Gestão do espaço urbano-regional, diante da realidade das...

  8. Absolute photoabsorption oscillator strengths by electron energy loss methods: the valence and S 2p and 2s inner shells of sulphur dioxide in the discrete and continuum regions (3.5-260 eV)

    International Nuclear Information System (INIS)

    Feng, R.; Cooper, G.; Burton, G.R.; Brion, C.E.; Avaldi, L.

    1999-01-01

    Absolute photoabsorption oscillator strengths (cross-sections) for the valence shell discrete and continuum regions of sulphur dioxide from 3.5 to 51 eV have been measured using high resolution (∼0.05 eV FWHM) dipole (e,e) spectroscopy. A wide-range spectrum, covering both the valence shell and the S 2p and 2s inner shells, has also been obtained from 5 to 260 eV at low resolution (∼1 eV FWHM), and this has been used to determine the absolute oscillator strength scale using valence shell TRK (i.e., S(0)) sum-rule normalization. The present measurements have been undertaken in order to investigate the recently discovered significant quantitative errors in our previously published low resolution dipole (e,e) work on sulphur dioxide (Cooper et al., Chem. Phys. 150 (1991) 237; 150 (1991) 251). These earlier measurements were also in poor agreement with other previously published direct photoabsorption measurements. We now report new absolute photoabsorption oscillator strengths using both high and low resolution dipole (e,e) spectroscopies. These new measurements cover a wider energy range and are much more consistent with the previously published direct photoabsorption measurements. The accuracy of our new measurements is confirmed by an S(-2) dipole sum-rule analysis which gives a static dipole polarizability for sulphur dioxide in excellent agreement (within 3.5%) with previously reported polarizability values. Other dipole sums S(u) (u=-1,-3 to -6,-8,-10) and logarithmic dipole sums L(u) (u=-1 to -6) are also determined from the presently reported absolute oscillator strength distributions. (Copyright (c) 1999 Elsevier Science B.V., Amsterdam. All rights reserved.)

  9. Caracteristicas demográficas e epidemiológicas de doadores aptos e inaptos clinicamente em um banco de sangue regional de Santa Cruz do Sul-RS

    Directory of Open Access Journals (Sweden)

    Cézane Priscila Reuter

    2011-11-01

    Full Text Available Analisar o perfil de doadores (aptos clínicos e não doadores (inaptos clínicos, com relação às características demográficas e socioeconômicas, o tipo de doação predominante, bem como os principais motivos para a inaptidão clínica. O estudo, de caráter transversal, contou com 2.876 sujeitos, de ambos os sexos. De acordo com os resultados, observa-se que os homens apresentam porcentagem bastante superior (65,0% em relação às mulheres (35,0%, quanto à aptidão clínica para a doação; já, as mulheres, apresentam maior porcentagem de inaptidão clínica (53,8%. De maneira geral, o perfil dos sujeitos, tanto aptos, quanto inaptos clinicamente, demonstra que, quanto às características demográficas e sócio-econômicas, a faixa etária predominante é de 18 a 29 anos, com ensino médio completo, solteiros e de etnia branca, sendo a maior parte semi-qualificado profissionalmente; quanto ao tipo de doação, há um destaque para a voluntária e, quanto ao motivo de inaptidão clínica, observam-se diferenças entre os sexos, onde os homens apresentam maior porcentagem de hematócrito elevado e hipertensão arterial e as mulheres, hematócrito baixo, gripe e hipotensão. Assim, pode-se concluir que a determinação do perfil do doador é importante para formular estratégias especificas para a captação de doadores de sangue.

  10. The role of natural E-region plasma turbulence in the enhanced absorption of HF radio waves in the auroral ionosphere:Implications for RF heating of the auroral electrojet

    Directory of Open Access Journals (Sweden)

    T. R. Robinson

    1994-03-01

    Full Text Available Physical processes which affect the absorption of radio waves passing through the auroral E-region when Farley-Buneman irregularities are present are examined. In particular, the question of whether or not it is legitimate to include the anomalous wave-enhanced collision frequency, which has been used successfully to account for the heating effects of Farley-Buneman waves in the auroral E-region, in the usual expression for the radio-wave absorption coefficient is addressed. Effects also considered are those due to wave coupling between electromagnetic waves and high-frequency electrostatic waves in the presence of Farley-Buneman irregularities. The implications for radio-wave heating of the auroral electrojet of these processes are also discussed. In particular, a new theoretical model for calculating the effects of high-power radio-wave heating on the electron temperature in an electrojet containing Farley-Buneman turbulence is presented.

  11. The role of natural E-region plasma turbulence in the enhanced absorption of HF radio waves in the auroral ionosphere:Implications for RF heating of the auroral electrojet

    Directory of Open Access Journals (Sweden)

    T. R. Robinson

    Full Text Available Physical processes which affect the absorption of radio waves passing through the auroral E-region when Farley-Buneman irregularities are present are examined. In particular, the question of whether or not it is legitimate to include the anomalous wave-enhanced collision frequency, which has been used successfully to account for the heating effects of Farley-Buneman waves in the auroral E-region, in the usual expression for the radio-wave absorption coefficient is addressed. Effects also considered are those due to wave coupling between electromagnetic waves and high-frequency electrostatic waves in the presence of Farley-Buneman irregularities. The implications for radio-wave heating of the auroral electrojet of these processes are also discussed. In particular, a new theoretical model for calculating the effects of high-power radio-wave heating on the electron temperature in an electrojet containing Farley-Buneman turbulence is presented.

  12. The risk of perinatal hepatitis B virus transmission: hepatitis B e antigen (HBeAg prevalence estimates for all world regions

    Directory of Open Access Journals (Sweden)

    Ott Jördis J

    2012-06-01

    Full Text Available Abstract Background HBeAg presence in childbearing-age women is a major determinant of perinatal hepatitis B virus (HBV transmission. The risk of developing chronic HBV infection and liver disease is highest at young age. Our aim was to assess perinatal HBV transmission risk by means of estimating age- and region-specific HBeAg prevalence. Methods Based on observed HBeAg seroprevalence data obtained from a systematic literature review, we modeled HBeAg prevalence using an empirical Bayesian hierarchical model. Age- and region-specific estimates were generated for 1990 and 2005. Results Globally, highest HBeAg prevalence of over 50 % was found in 0–9 years old girls. At reproductive age, HBeAg prevalence was 20-50 %. Prevalence was highest in young females in East Asia in 1990 (78 %, the infection was less common in Sub-Saharan and North Africa. Regional differences in prevalence were smaller in 2005. There was an overall decrease in HBeAg between 1990 and 2005, which was strongest among girls in Oceania (23.3 % decline, South and South-East Asia (14 % decline. However, in these regions, prevalence remained high at 67 % among young females in 2005. Smaller decreases were observed in women at reproductive age, at which 24-32 % of all HBsAg-positive women were HBeAg-positive in 2005, with lowest prevalence in Southern Sub-Saharan Africa and highest prevalence in Oceania and South-East Asia. Conclusions HBeAg estimates are crucial for understanding the epidemiology of HBV and for prioritizing implementation of WHO`s prevention recommendations for all infants to receive the first dose of hepatitis B vaccine within 24 hours of birth. Results will have importance as access to treatment for chronic HBV infection is expanded.

  13. A Study of the Energy Dependence of the Th 232 Capture Cross Section in the Energy Region 0.1 to 3.4 eV

    Energy Technology Data Exchange (ETDEWEB)

    Lundgren, G

    1967-11-15

    Using the fast chopper at the Stockholm reactor R1 a comparison between the (n, {gamma}) cross sections for thorium and copper has been made in the energy interval 0.1 to 3.4 eV. The (n, {gamma}) cross section for copper follows the 1/v law sufficiently well in this energy interval to be used as a 1/v standard. The deviation at 3.4 eV does not exceed 5 %. The capture cross section, {sigma}, for thorium decreases more rapidly than 1/v and the deviation is found to be close to 60 % at 3.4 eV. If one assumes that the deviation is caused essentially by a single negative resonance this should be located at 5.1 {+-} 0.5 eV. Furthermore, if a value of 24 meV for {gamma}{sub {gamma}}, the radiation width for the negative resonance, is used one finds that {gamma}{sub n}{sup 0}, the reduced neutron width for the same resonance, amounts to 1.82 {+-} 0.25 meV. Using these parameters together with the resonance parameters for the positive resonances a value of the total microscopic scattering cross section at 0.025 eV has been calculated as 12.2 {+-} 0.4 b. A value of the contributions above 0.5 eV to the resonance integral from the 'tail' of the negative resonance and the 1/v - parts of the positive resonances has also been calculated giving the result 1.6 b. Finally, the g-factor (Westcott's nomenclature) for a Maxwellian spectrum at 20 deg C becomes 0.994.

  14. Characterization of the regions from E. coli 16 S RNA covalently linked to ribosomal proteins S4 and S20 after ultraviolet irradiation

    International Nuclear Information System (INIS)

    Ehresmann, B.; Backendorf, C.; Ehresmann, C.; Ebel, J.P.

    1977-01-01

    The use of ultraviolet irradiation to form photochemical covalent bonds between the 16 S RNA and a ribosomal protein is a reliable method to check RNA regions which are interacting with the protein. This technique was successfully used to covalently link RNA or DNA and specific proteins in several cases. In the case of ribosome, it has been shown that the irradiation of 30 S and 50 S subunits using high doses of ultraviolet light allowed the covalent binding of almost all of the ribosomal proteins to the 16 S or 23 S RNAs. Using mild conditions, only proteins S7 and L4 could be covalently linked to the 16 S and 23 S RNAs, respectively, and the 16 S RNA region linked to protein S7 has now been characterized. The specificity of the photoreaction was demonstrated earlier and the tryptic peptides from proteins S4 and S7, photochemically linked to the 16 S RNA complexes, were identified. A report is presented on the sequences of the RNA regions which can be photochemically linked to proteins S4 and S7 after ultraviolet irradiation of the specific S4-16 S RNA and 20 S-16 S RNA complexes

  15. Balto-Chernomor'e v dvojnoj sisteme Evropa-Evrazija [The Baltic-Pontic region in the Europe-Eurasia dual system

    Directory of Open Access Journals (Sweden)

    Ilyin Mikhail

    2012-01-01

    Full Text Available This article considers the Baltic-Pontic Sea region not only as a geographical space of Intermarium (Międzymorze, Tarpjūris etc. but also as Intermundium or the interface of European and Russian (Eurasian civilization. The study sets out to clarify the logic of changing patterns shaping this geopolitical area. To this end, the concept of the Baltic-Pontic conflict system proposed by Vadim Tsymbursky is applied and further developed. In contrast to his agent-focused vehicle of analysis disclosing the power interactions in Intermarium, the authors advance an alternative structure-focused model of the Baltic-Pontic system (BPS as a multidimensional evolving space of heterogeneous interactions, which include cooperation. The authors suggest applying the BPS models in interpreting and clarifying historical developments in the area from the late 14th century until the present. The article analyses the spatial, geopolitical and geochronopolitical characteristics of the region, as well as the models of intercivilisational interaction between Europe and Eurasia. The author addresses the issue of the political identity of the region and its ability to play an independent role in the world politics.

  16. Convergência na variação local e regional da riqueza de espécies de insetos galhadores

    OpenAIRE

    Carneiro, Marco A.A.; Fernandes, G.W.; De Souza, O.F.F.

    2005-01-01

    Foram investigados os determinantes locais e regionais da riqueza de insetos indutores de galhas sobre o arbusto dióico Baccharis concinna Barroso (Asteraceae) na porção sudeste da Cadeia do Espinhaço, MG. O número total de espécies de insetos indutores de galhas e a riqueza de Cecidomyiidae (Diptera) foram influenciados pelo sexo da planta. Plantas masculinas apresentaram maior riqueza de insetos indutores de galhas do que plantas femininas, corroborando a hipótese da herbivoria mediad...

  17. Measurement of the average number of prompt neutrons emitted per fission of 235U relative to 252Cf for the energy region 500 eV to 10 MeV

    International Nuclear Information System (INIS)

    Gwin, R.; Spencer, R.R.; Ingle, R.W.; Todd, J.H.; Weaver, H.

    1980-01-01

    The average number of prompt neutrons emitted per fission ν/sub p/-bar(E), was measured for 235 U relative to ν/sub p/-bar for the spontaneous fission of 252 Cf over the neutron energy range from 500 eV to 10 MeV. The samples of 235 U and 252 Cf were contained in fission chambers located in the center of a large liquid scintillator. Fission neutrons were detected by the large liquid scintillator. The present values of ν/sub p/-bar(E) for 235 U are about 0.8% larger than those measured by Boldeman. In earlier work with the present system, it was noted that Boldeman's value of ν/sub p/-bar(E) for thermal energy neutrons was about 0.8% lower than obtained at ORELA. It is suggested that the thickness of the fission foil used in Boldeman's experiment may cause some of the discrepancy between his and the present values of ν/sub p/-bar(E). For the energy region up to 700 keV, the present values of ν/sub p/-bar(E) for 235 U agree, within the uncertainty, with those given in ENDF/B-V. Above 1 MeV the present results for ν/sub p/-bar(E) range about the ENDF/B-V values with differences up to 1.3%. 6 figures, 1 table

  18. Neutron capture cross section measurement of 238U at the n TOF CERN facility with C6D6 scintillation detectors in the energy region from 1 eV to 700 keV

    CERN Document Server

    Mingrone, F.

    2017-01-01

    The aim of this work is to provide a precise and accurate measurement of the 238U(n,g) reaction cross section in the energy region from 1 eV to 700 keV. This reaction is of fundamental importance for the design calculations of nuclear reactors, governing the behaviour of the reactor core. In particular, fast reactors, which are experiencing a growing interest for their ability to burn radioactive waste, operate in the high energy region of the neutron spectrum. In this energy region most recent evaluations disagree due to inconsistencies in the existing measurements of up to 15%. In addition, the assessment of nuclear data uncertainty performed for innovative reactor systems shows that the uncertainty in the radiative capture cross-section of 238U should be further reduced to 1-3% in the energy region from 20 eV to 25 keV. To this purpose, addressed by the Nuclear Energy Agency as a priority nuclear data need, complementary experiments, one at the GELINA and two at the n_TOF facility, were proposed and carrie...

  19. Neutron capture cross section measurement of $^{238}$U at the n_TOF CERN facility in the energy region from 1 eV to 700 keV

    CERN Document Server

    Mingrone, F; Vannini, G; Colonna, N; Gunsing, F; Zugec, P; Altstadt, S; Andrzejewski, J; Audouin, L; Barbagallo, M; Becares, V; Becvavr, F; Belloni, F; Berthoumieux, E; Billowes, J; Bosnar, D; Brugger, M; Calviani, M; Calvino, F; Cano-Ott, D; Carrapico, C; Cerutti, F; Chiaveri, E; Chin, M; Cortes, G; Cortes-Giraldo, M A; Diakaki, M; Domingo-Pardo, C; Duran, I; Dressler, R; Eleftheriadis, C; Ferrari, A; Fraval, K; Ganesan, S; Garcia, A R; Giubrone, G; Goncalves, I F; Gonzalez-Romero, E; Griesmayer, E; Guerrero, C; Hernandez-Prieto, A; Jenkins, D G; Jericha, E; Kadi, Y; Kappeler, F; Karadimos, D; Kivel, N; Koehler, P; Kokkoris, M; Krticka, M; Kroll, J; Lampoudis, C; Langer, C; Leal-Cidoncha, E; Lederer, C; Leeb, H; Leong, L S; Lo Meo, S; Losito, R; Mallick, A; Manousos, A; Marganiec, J; Martinez, T; Mastinu, P F; Mastromarco, M; Mendoza, E; Mengoni, A; Milazzo, P M; Mirea Horia, M; Mondalaers, W; Paradela, C; Pavlik, A; Perkowski, J; Plompen, A; Praena, J; Quesada, J M; Rauscher, T; Reifarth, R; Riego, A; Robles, M S; Rubbia, C; Sabate-Gilarte, M; Sarmento, R; Saxena, A; Schillebeeckx, P; Schmidt, S; Schumann, D; Tagliente, G; LTain, J; Tarrio, D; Tassan-Got, L; Tsinganis, A; Valenta, S; Variale, V; Vaz, P; Ventura, A; Vermeulen, M J; Vlachoudis, V; Vlastou, R; Wallner, A; Ware, T; Weigand, M; Weiss, C; Wright, T

    2016-01-01

    The aim of this work is to provide a precise and accurate measurement of the $^{238}$U(n,$\\gamma$) reaction cross section in the energy region from 1 eV to 700 keV. This reaction is of fundamental importance for the design calculations of nuclear reactors, governing the behaviour of the reactor core. In particular, fast reactors, which are experiencing a growing interest for their ability to burn radioactive waste, operate in the high energy region of the neutron spectrum. In this energy region most recent evaluations disagree due to inconsistencies in the existing measurements of up to 15%. In addition, the assessment of nuclear data uncertainty performed for innovative reactor systems shows that the uncertainty in the radiative capture cross-section of $^{238}$U should be further reduced to 1-3% in the energy region from 20 eV to 25 keV. To this purpose, addressed by the Nuclear Energy Agency as a priority nuclear data need, complementary experiments, one at the GELINA and two at the n_TOF facility, were pr...

  20. Teores de As, Pb, Cd e Hg e fertilidade de solos da região do Vale do Alto Guaporé, sudoeste do estado de Mato Grosso Contents of As, Pb, Cd e Hg and fertility of soils of Vale do Alto Guapore region, south-west of Mato Grosso state

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Pereira Pierangeli

    2009-03-01

    Full Text Available O diagnóstico da fertilidade e teores de elementos-traço (ETs em solos é importante, pois estes dados são escassos na literatura para áreas de transição Pantanal-Cerrado-Floresta Amazônica. Esse trabalho avaliou diversos parâmetros relacionados à fertilidade, teores biodisponíveis de Fe, Mn, Zn, Cu e B e semitotais de As, Cd, Hg e Pb de solos do Vale do Alto Guaporé, região sudoeste do estado de Mato Grosso. Foram coletadas amostras de solos (0-0,20 e 0,20-0,40 m de profundidade em áreas de vegetação nativa (VN, pastagem (AP, cultura anual (CA e garimpo de ouro (G. As amostras foram analisadas conforme métodos de rotina para avaliação da fertilidade do solo e ETs pelo método SW-3051A e os resultados médios comparados com os valores de referência de qualidade (VRQ para solos estipulados pela Companhia de Tecnologia de Saneamento Ambiental (CETESB. Teores mais elevados de As e Hg foram verificados em VN e G com médias, respectivamente, iguais a 43,9 e 101,13 para o As; e 0,12 e 0,14 mg kg-1 para o Hg. Exceto Pb, vários locais de amostragem apresentaram teores dos ETs superiores ao VRQ: 46% em VN; 60% em G; 28% em CA; e 44% em AP, para o As; 20,8; 50; 55; e 22% em VN, G, CA e AP, respectivamente, para o Cd; 75; 65 e 67% das áreas de VN, G e CA e AP, respectivamente, para o Hg. A saturação por bases foi alta (60-80% em 51,5% das amostras, enquanto o P foi baixo em todas áreas. Valores de referência de qualidade de solo para o As e Hg devem ser estipulados para solos dessa região, tendo em vista que os teores observados em áreas nativas foram superiores ao VRQ.The fertility and trace elements diagnosis of soils is important for agricultural and environmental purposes, because there is little data available on the Pantanal-Cerrado-Floresta Amazônica transitional areas. This work evaluated many parameters relative to the fertility, Fe, Mn, Zn, Cu and B bioavailability, and total content of As, Cd, Hg and Pb in soils of

  1. I massimali di crescita: effetti territoriali e sulla struttura del sistema bancario. (Growth limits on bank assets: regional effects and the structure of the banking system.

    Directory of Open Access Journals (Sweden)

    A. NICCOLI

    2013-12-01

    Full Text Available Negli ultimi anni , la politica monetaria italiana è stata basata sempre più sui controlli amministrativi . Tra le tesi , i più significativi sono i limiti della crescita e vincoli della composizione del portafoglio. Questo articolo ha esaminato l' effetto dei limiti di crescita , ossia il loro effetto , da un punto di vista geografico della struttura e sul sul bancario italiano .In recent years, Italian monetary policy has become increasingly based on administrative controls. Among theses, the most important are the limits of growth and constraints of the portfolio composition. The former impose a maximum growth rate of total loans in lire on banks, while the latter obliges them to invest a given amount of the increases in deposits in securities with specific characteristics. The present article examines a side effect of growth limits, namely their effect from a geographical point of view and on the structure of the Italian banking system. In particular, the author shows that the occurrence of growth ceilings for a given bank is greater the more rapid the increase in its deposits and the smaller the geographical area in which it operates. JEL: E51, E52, G21

  2. Desarrollo social y mortalidad infantil, 1977-1986, Cuba: un análisis regional Desenvolvimento social e mortalidade infantil, 1977-1986, Cuba: análise regional Social development and infant mortality, 1977-1986, Cuba: a regional analysis

    Directory of Open Access Journals (Sweden)

    Guillermo Gonzalez Perez

    1990-06-01

    Full Text Available En Cuba, la tasa de mortalidad infantil (TMI se redujo entre 1970 y 1986 en un 65%. La TMI alcanzada en 1986 -13,6%o - ubica al país a la vanguardia de Latinoamérica en cuanto a salud materno-infantil. Sin embargo, subsisten diferencias interprovinciales en la mortalidad durante el primer año de vida. Mediante el empleo de técnicas de regresión múltiples, se intenta identificar los factores sociodemográficos o relacionados con los servicios de salud que más han incidido en el descenso de la TMI en Cuba y provincias en el decenio estudiado, así como las variables que mejor explican las diferencias interprovinciales en cada año. Son factores sociodemográficos los que mayoritariamente explican la evolución de la TMI; por otra parte, si bien la proporción de nacidos vivos con bajo peso y la tasa bruta de natalidad explican en primera instancia las diferencias interprovinciales en el nivel de la mortalidad infantil en cada año, un análisis más cuidadoso permite establecer que son variables eminentemente socieconómicas las que están detrás de tales diferencias.Em Cuba, entre os anos de 1970 a 1986 a taxa de mortalidade infantil (TMI reduziu em 65%. A TMI obtida em 1986 -13,6%o - foi a mais baixa no contexto lationamericano, embora a nível regional o comportamento da taxa não tem sido homogêneo. Com o emprego da técnica de regressão múltipla, pretendeu-se identificar aqueles fatores socio-demográficos e dos serviços de saúde que mais têm incidido no declínio da mortalidade infantil em Cuba, no período acima descrito, bem como as variáveis que melhor explicam as diferenças inter-regionais do referido indicador. Os fatores socio-demográficos explicam a evolução da TMI em Cuba. Embora a queda da natalidade e a redução da proporção de recém-nascidos com baixo peso ao nascer expliquem - em princípios - as diferenças inter-regionais quanto a TMI, outros fatores socio-econômicos podem explicar tais diferen

  3. Economia, agricultura e clima através de modelo digital do terreno na microrregião Vale do Ipanema | Economy, agriculture and climate through model digital terrain in micro region Vale of Ipanema

    Directory of Open Access Journals (Sweden)

    Nina Iris Verslype

    2016-04-01

    Full Text Available Partindo da ideia que a agricultura está amplamente ligada aos fatores climáticos como temperatura e umidade relativa do ar, e que ela pode contribuir para o aumento de renda, geração de emprego, inclusive de verificar novas fronteiras agrícolas e consequentemente o aumento do PIB e IDH, que é considerado baixo na microrregião. Nesse estudo, foi feita a modelagem digital do terreno da microrregião Vale do Ipanema e de seus municípios, para os parâmetros de precipitação, temperatura, PIB, IDH e população. Os municípios analisados foram: Águas Belas, Buíque, Itaíba, Pedra, Tupanatinga e Venturosa.Com as análises climáticas foi possível perceber que a microrregião apresenta uma baixa capacidade hídrica, devido aos períodos longos de estiagem e as chuvas irregulares, mas mesmo assim a economia local se destaca com a maior produção leiteira pernambucana e como um grande contribuinte à agricultura familiar. Starting from the idea that agriculture is largely linked to climatic factors such as temperature and relative humidity, and it can contribute to increased income, employment generation, including checking new agricultural frontiers and hence the increase in GDP and HDI, which is considered low in the micro. In this study, was made the digital terrain modeling of the micro region of Ipanema Valley, and its municipalities for the precipitation parameters, temperature, GDP, HDI and population, in order to view the development of the region studied. Municipalities analyzed were: Águas Belas, Buíque, Itaíba, Pedra, Tupanatinga and Venturosa. With climate analysis was possible to realize that the micro-region has a low water capacity due to long periods of drought and erratic rainfall, yet the economy site stands out with the highest milk production Pernambuco and as a major contributor to family farming.

  4. A Contribuição da universidade pública para a inovação e o desenvolvimento regional: a percepção de gestores e pesquisadores

    Directory of Open Access Journals (Sweden)

    Maria Antonieta Leopoldi

    2013-01-01

    Full Text Available This article presents a case study about the Polo Universitário de Volta Redonda (PUVR-UFF, a new campus of Federal Fluminense University (UFF, located in the Médio Paraíba Fluminense Region (RMP-RJ. The aim is to identify the limits and possibilities of contribution of a public university for innovation and regional development. The theoretical framework is based on the concept of entrepreneurial university. We conducted a qualitative study with 5 managers of the central structure of UFF (UFF-Sede and 14 managers and researchers of PUVR-UFF. The mains results indicate that are incipient efforts undertaken by PUVR-UFF to stimulate innovative activities among its faculty, as well as actions that stimulate regional development. Interviewees perceived that the major barriers of PUVR-UFF are related to the improvement of bureaucratic processes of the university, the expanding the work with the society and the establishment of mechanisms to encourage the transformation of basic research in technology and innovation. The survey data also indicate the importance of academic leaders capable of mobilizing the university in conducting activities of interaction with society, encouraging an entrepreneurial university.

  5. Ophiuroidea das regiões antártica e subantártica: 1. sobre três espécies de Gorgonocephalidae e Ophiacanthidae Ophiuroidea from antarctic and subantarctic regions: 1. on three species of Gorgonocephalidae and Ophiacanthidae

    Directory of Open Access Journals (Sweden)

    Ana Maria Gouveia Monteiro

    1983-01-01

    Full Text Available É estudada a distribuição geográfica e a variação de caracteres morfológicos de três espécies de ofiuroides (OpiLacantha antartica, Astrotoma agassizzi e Gorgonecephalus chilensis das regiões Antártica e Subantãrtica. São também apresentadas observações sobre biologia reprodutiva.The geographical distribution and the variation of morphological characters of three (Gorgonecephalus chilensis, Astroma agassizii, Ophiacantha antartica from the Antarctic and Subantarctic regions are studied. Observations on reproductive biology are presented.

  6. Efeito da temperatura, pH e vestígios de Hg2+ e Pb2+ na acti­vidade de desidrogenases e urease num solo da região de Évora Effect of temperature, pH and Hg2+ and Pb2+ traces in dehydrogenaseand urease activities of a soil from Évora region

    Directory of Open Access Journals (Sweden)

    M. R. Martins

    2010-01-01

    Full Text Available As actividades das enzimas no solo são um importante indicador da sua qualida­de. Neste estudo procedeu-se à caracteri­zação da actividade enzimática de desi­drogenases (EC 1.1.1 e da urease (EC 3.5.1.5 de um solo sob Olea europeae L. da região de Évora. As constantes cinéti­cas Km e Vmáx, foram determinadas usando como substratos o cloreto de p­-iodonitrotetrazolio (INT e a ureia, res­pectivamente. Foi avaliado o efeito nas referidas actividades provocado pelo pH, temperatura e vestígios de Hg2+ e de Pb2+. As actividades máximas obtiveram-se a pH = 8,5 e 40 ºC, com Km= 0,5 mM e Vmáx = 5,4 µmol min-1 g-1, para a activida­de de desidrogenases e a pH = 10 e 37 ºC, com Km = 25,7 mM e Vmáx = 2,0x10-2 µmol min-1 g-1, para a urease. Estas acti­vidades foram inibidas por diferentes concentrações de Hg2+, mas apenas a acti­vidade da urease foi inibida pelo Pb2+. Estes resultados são comparáveis com os referidos na literatura para estes enzimas.Enzyme activities are often used as in­dicator of soil quality. This study reports on dehydrogenase (EC 1.1.1 and urease (EC 3.5.1.5 activities of a soil under Olea europaea L. from Évora region. Kinetic constants Km and Vmax were determined using p-iodonitrotetrazolium chloride (INT and urea, respectively. Effects of pH, temperature and Hg2+ and Pb2+ traces on both activities were determined. Maximal activity was obtained at pH = 8.5 and 40ºC, Km = 0.5 mM and Vmax=5,4µmol min-1 g-1 , for dehydro­genase and at pH = 10 and 37 ºC, Km = 25.7 mM and Vmax = 2.0x10-2 µmol min-1 g-1, for urease. These activities were in­hibited by different concentrations of Hg2+, but only the urease activity was in­hibited by Pb2+. Results of this study are comparable to those reported in the litera­ture for these enzymes.

  7. Influência regional no consumo precoce de alimentos diferentes do leite materno em menores de seis meses residentes nas capitais brasileiras e Distrito Federal Regional influence on early consumption of foods other than breast milk in infants less than 6 months of age in Brazilian State capitals and the Federal District

    Directory of Open Access Journals (Sweden)

    Silvia Regina Dias Medici Saldiva

    2011-11-01

    Full Text Available Objetivou-se avaliar a influência regional no consumo precoce de alimentos diferentes do leite materno em menores de seis meses residentes nas capitais brasileiras. Analisaram-se dados de 18.929 crianças da II Pesquisa de Prevalência de Aleitamento Materno nas Capitais Brasileiras - 2008. As frequências do consumo de chá, sucos, leite artificial e mingau/papa foram calculadas para as capitais das cinco regiões brasileiras. Curvas do consumo foram obtidas pela análise de logitos e estimativas das razões de prevalência (RP por modelos de Poisson. O consumo de leite artificial foi maior quando comparado aos demais alimentos em todas as capitais. As capitais do Sul apresentaram a maior razão de prevalência para o consumo de chá (RP = 2,37 e as do Nordeste e Sudeste, para o consumo de outros tipos de leite (RP = 1,50 e 1,47 e de suco (RP = 1,57 e 1,55. Nas capitais do Nordeste, o consumo precoce de mingau/papa foi maior (RP = 3,0. A região tem influência no consumo precoce de alimentos, o que deve ser levado em consideração na elaboração de políticas públicas.The aim was to assess regional influences on food consumption in infants less than six months of age. A cross-sectional study was conducted in a sample of 18,929 infants participating in the Second Survey on Breastfeeding Prevalence in Brazilian State Capitals and the Federal District in 2008. Consumption rates for tea, fruit juices, formula milk, and porridge were calculated for the State capitals from the five geographic regions of the country. Food consumption was estimated by logit analyses and Poisson models. Differences in food consumption profile were observed between the different regions: tea was more common in State capitals in the South (RP = 2.37, while non-maternal milk (RP = 1.50 and 1.47 and juices (RP = 1.57 and 1.55 were more frequent in the Northeast and Southeast, respectively. Porridge was more common in the Northeast (RP = 3.0. Brazil's geographic regions

  8. General epidemiological parameters of viral hepatitis A, B, C, and E in six regions of China: a cross-sectional study in 2007.

    Science.gov (United States)

    Lu, Jian; Zhou, Yongdong; Lin, Xiaojing; Jiang, Yongzhen; Tian, Ruiguang; Zhang, Yonghui; Wu, Jia; Zhang, Fengwei; Zhang, Yong; Wang, Yue; Bi, Shengli

    2009-12-24

    Viral hepatitis is a serious health burden worldwide. To date, few reports have addressed the prevalence of hepatitis A, B, C, and E in China. Therefore, the general epidemiological parameters of viral hepatitis remain unknown. In this cross-sectional study, we performed a serological prevalence analysis of viral hepatitis A, B, C, and E in 8,762 randomly selected Chinese subjects, which represented six areas of China. The overall prevalence of anti-Hepatitis C virus antibody (anti-HCV) was 0.58%, which was much lower than was estimated by WHO. The prevalences of Hepatitis B virus surface antigen (HBsAg), anti-Hepatitis B virus surface protein antibody (HBsAb), and anti-Hepatitis B virus core protein antibody (HBcAb) were 5.84%, 41.31%, and 35.92%, respectively, whereas in the group of subjects less than 5 years old, these prevalences were 1.16%, 46.77%, and 8.69% respectively, which suggests that the Hepatitis B virus (HBV)-carrier population is decreasing, and the nationwide HBV vaccine program has contributed to the lowered HBV prevalence in the younger generation in China. Meanwhile, a large deficit remains in coverage provided by the national HBV immune program. In addition, our data suggested the possibility that HBsAb may not last long enough to protect people from HBV infection throughout life. The overall prevalence of anti-Hepatitis A virus antibody (anti-HAV) and anti-Hepatitis E virus antibody (anti-HEV) were as high as 72.87% and 17.66%, respectively. The indices increased with age, which suggests that a large proportion of Chinese adults are protected by latent infection. Furthermore, the pattern of HEV infection was significantly different among ethnic groups in China. Our study provided much important information concerning hepatitis A, B, C, and E prevalence in China and will contribute to worldwide oversight of viral hepatitis.

  9. Compensation of Handicap and Autonomy Loss through e-Technologies and Home Automation for Elderly People in Rural Regions: An Actual Need for International Initiatives Networks

    Science.gov (United States)

    Billonnet, Laurent; Dumas, Jean-Michel; Desbordes, Emmanuel; Lapôtre, Bertrand

    To face the problems of elderly and disabled people in a rural environment, the district of Guéret (department of Creuse, France) has set up the "Home automation and Health Pole". In association with the University of Limoges, this structure is based on the use of e-technologies together with home automation techniques. In this frame, many international collaborations attempts have started through a BSc diploma. This paper sums up these different collaborations and directions.

  10. Avaliação da qualidade de correctivos orgânicos comercializados na região de Entre Douro e Minho Quality evaluation of organic composts commercialized in the region of Entre Douro e Minho

    Directory of Open Access Journals (Sweden)

    J. Oliveira

    2009-01-01

    Full Text Available Quando não devidamente maturados, os compostos orgânicos podem causar fitotoxicidade, prejudicando o desenvolvimento das culturas e a produção. Esse efeito está frequentemente relacionado com a libertação de ácidos orgânicos de baixo peso molecular, de azoto na forma amoniacal e de dióxido de carbono. Este estudo tem como objectivo avaliar a qualidade de correctivos orgânicos em comercialização no Entre Douro e Minho. Para tal, procedeu-se a uma amostragem dos correctivos orgânicos disponíveis em treze cooperativas agrícolas da região do Entre Douro e Minho, e à elaboração de um pequeno inquérito. Na apreciação da qualidade, utilizaram-se os métodos químicos e biológicos. Os resultados obtidos permitem concluir que a qualidade dos compostos deve ser melhorada. Importa referir que, embora os resultados da apreciação da qualidade dos compostos efectuados com base na proposta de norma para a apreciação da qualidade do composto orgânico de Souteiro & Baptista (2001 indiquem que todos os compostos avaliados apresentam parâmetros químicos limitativos, os resultados da avaliação biológica revelam-se mais positivos.The maturity degree is a basic parameter in the apreciation of the quality of organic composts. When unstable or without enough maturity the organic amendment can cause phytotoxity by liberation of volatile organic acids, ammonium or carbon dioxide. With the present work we attempt to quantify the effective quality of composts in comercialization at Entre-Douro-e Minho farmers associations. Quality of composts were evaluated by chemical and biological methods. The results allow us to conclude that the quality of the organic composts must be improved. While the results of the chemical evaluation classify all samples as bad, biological evaluations bellow a better judgement.

  11. [Inheritable phenotypic normalization of rodent cells transformed by simian adenovirus SA7 E1 oncogenes by singled-stranded oligonucleotides complementary to a long region of integrated oncogenes].

    Science.gov (United States)

    Grineva, N I; Borovkova, T V; Sats, N V; Kurabekova, R M; Rozhitskaia, O S; Solov'ev, G Ia; Pantin, V I

    1995-08-01

    G11 mouse cells and SH2 rat cells transformed with simian adenovirus SA7 DNA showed inheritable oncogen-specific phenotypic normalization when treated with sense and antisense oligonucleotides complementary to long RNA sequences, plus or minus strands of the integrated adenovirus oncogenes E1A and E1B. Transitory treatment of the cells with the oligonucleotides in the absence of serum was shown to cause the appearance of normalized cell lines with fibroblastlike morphology, slower cell proliferation, and lack of ability to form colonies in soft agar. Proliferative activity and adhesion of the normalized cells that established cell lines were found to depend on the concentration of growth factors in the cultural medium. In some of the cell lines, an inhibition of transcription of the E1 oncogenes was observed. The normalization also produced cells that divided 2 - 5 times and died and cells that reverted to a transformed phenotype in 2 - 10 days. The latter appeared predominantly upon the action of the antisense oligonucleotides.

  12. Variabilidade de goethita e hematita via dissolução redutiva em solos de região tropical e subtropical Goethite and hematite variability via reductive dissolution in soils from tropical and subtropical regions

    Directory of Open Access Journals (Sweden)

    Alberto Vasconcellos Inda Junior

    2005-12-01

    Full Text Available Dezenove amostras de horizontes B latossólicos, uma de B plíntico, uma de B incipiente e uma de horizonte Cr foram submetidas a dissoluções seletivas da goethita e da hematita por ditionito-citratro-bicarbonato de sódio a 20 ºC em intervalos de tempo entre 5 e 3.840 minutos. O diâmetro médio do cristal (DMC, área superficial específica (ASE e substituição do ferro por Al (substituição por Al3+ da goethita e da hematita nas amostras foram estimados, por difratometria de raios X (DRX, em subamostras não tratadas e em subamostras tratadas selecionadas ao longo das dissoluções seletivas. O controle das fases de goethita e hematita que persistiram após cada etapa da dissolução seletiva foi realizado pelo método da difratometria diferencial de raios X (DDRX. A cinética dissolutiva dos cristais foi descrita por meio da segmentação das curvas de dissolução do ferro no tempo em intervalos em que o comportamento dissolutivo foi linear. As taxas de dissolução nos diferentes segmentos lineares foram estimadas a partir do coeficiente angular da reta relativa a cada segmento. Em amostras goethíticas latossólicas, a metodologia discriminou diferentes fases de goethita (populações heterogêneas quanto à substituição por Al3+, DMC e ASE e ofereceu condições para classificar o grau de estabilidade da goethita em baixa, média, alta e muito alta estabilidade. Amostras goethíticas oriundas de ambientes pedogênicos jovens e amostras hematíticas latossólicas caracterizaram-se pela maior homogeneidade de seus cristais, classificados como de baixa e média estabilidade. Nas amostras goethíticas, a proporção de cristais com maior estabilidade (alta substituição por Al3+ e cristalinidade em cada população mostrou associação positiva com a proporção de gibbsita em relação a caulinita nas amostras. A hematita apresentou menor resistência à dissolução por redução em relação à goethita, exceto quando a última

  13. O diagnóstico das zonas mortas na cóclea e sua importância no processo de reabilitação auditiva Diagnosing cochlear "dead" regions and its importance in the auditory rehabilitation process

    Directory of Open Access Journals (Sweden)

    Cristiane Padilha

    2007-08-01

    Full Text Available Cada vez mais na prática da audiologia é indispensável um bom diagnóstico audiológico, para que se tenha conhecimento das necessidades do paciente para seleção e adaptação de próteses auditivas. OBJETIVO: Expor literaturas recentes que referem conceitos de zonas mortas na cóclea, estratégias de diagnóstico e a importância deste no processo de seleção e adaptação de próteses auditivas. METODOLOGIA: Realizou-se um levantamento bibliográfico sobre zonas mortas na cóclea. As zonas mortas na cóclea foram descritas como regiões onde as células ciliadas internas e/ou neurônios adjacentes não se encontram funcionais. Assim, nessas regiões a informação gerada pela vibração da membrana basilar não é transmitida ao sistema nervoso central. Porém, um tom com freqüência correspondente a zona morta, desde que suficientemente intenso, pode ser percebido em regiões próximas a esta zona, onde às células ciliadas internas e/ou fibras nervosas ainda apresentam-se funcionais. CONCLUSÃO: A identificação das zonas mortas na cóclea está sendo utilizada visando melhores resultados no processo de seleção e adaptação de próteses auditivas, pois as informações geradas pelas CCI ao nervo auditivo são importantes para um melhor reconhecimento dos sons, principalmente os sons da fala.A good audiologic diagnosis is increasingly more important in the practice of audiology, in order to understand patients’ needs for selection and fitting of hearing aid devices. AIM: Show recent literature that mention the concept of cochlear dead regions, diagnostic strategies and its relevance in the process of selection and fitting of hearing aids. METHODS: to carry out a bibliographical survey on dead cochlear regions. Dead cochlear regions were described as regions where inner hair cells and/or adjacent neurons do not work. Therefore, in these regions, the information generated by basilar membrane vibration is not transmitted to the

  14. O ENSINO DE GEOGRAFIA REGIONAL DA PARAÍBA: ESPAÇO AGRÁRIO, USO DO SOLO E DIFUSÃO DA INFORMAÇÃO – APRESENTAÇÃO

    OpenAIRE

    Emilia Moreira

    2003-01-01

    Este número da revista “Cadernos do LOGEPA – Série Texto Didático” tem por objetivo divulgar os resultados do Projeto “O Ensino de Geografia Regional da Paraíba: espaço agrário, uso do solo e difusão da informação”, desenvolvido no âmbito dos Laboratórios de Geografia da Paraíba (LOGEPA) e de Ensino e Pesquisa em Análise Espacial (LEPAN) do Departamento de Geociências da UFPB, com o apoio do Programa de Iniciação à Docência (PROLICEN –UFPB). Ele reuniu um grupo de cinco docentes do Departamen...

  15. Difusão do agronegócio e reestruturação urbano-regional no Oeste Baiano

    Directory of Open Access Journals (Sweden)

    Camila Dutra dos Santos

    2016-07-01

    Full Text Available As redes agroindustriais, com apoio deliberado do Estado, vêm se estabelecendo nos lugares e produzindo uma reestruturação produtiva condizente com seus interesses, atingindo tanto a base técnica quanto a econômica e social do setor agrícola, e promovendo a formação e/ou a reestruturação de regiões que passam a encarnar especializações territoriais. O Oeste Baiano se configura como um desses exemplos de região funcional ao agronegócio, contendo, principalmente a partir da década de 1980, condições favoráveis à expansão dessa atividade, com investimento maciço de capital público e privado na tecnificação do território. Essa região tem sua organização socioespacial atual pautada por redes agroindustriais que participam dos circuitos espaciais de produção e círculos de cooperação da produção moderna de grãos, principalmente da soja. Os conteúdos urbanos e os papéis regionais das principais cidades do Oeste Baiano resultam de uma crescente integração entre o agronegócio e os circuitos da economia urbana, transformando tais cidades em espaços funcionais às exigências produtivas do campo moderno. Nessa região, a difusão do agronegócio tem-se processado de forma conservadora e excludente, traduzindo-se no reforço de históricas desigualdades socioespaciais, bem como na criação de novas. Résumé LA DIFFUSION DE L’AGROBUSINESS ET RESTRUCTURATION URBAINE-RÉGIONALE DANS L’OUEST BAIANO Les réseaux agro-industrielles, avec le soutien delibere de l’Etat, sont établis dans des lieux et provoquent une restructuration productive compatible avec leurs intérêts, changeant la base technique et aussi économique et sociale du secteur agricole, et provoquant la formation e/ou la restructuration des régions qui viennent à incarner des spécialisations territoriales. L’Ouest de Bahia, situé au Nordeste du Brésil, est configuré comme un exemple de ces régions fonctionnels au l

  16. Characteristics of the E - and F -region field-aligned irregularities in middle latitudes: Initial results obtained from the Daejeon 40.8 MHz VHF radar in South Korea

    Directory of Open Access Journals (Sweden)

    Young-Sil Kwak

    2014-03-01

    Full Text Available We present preliminary observations of the field-aligned-irregularities (FAIs in the E and F regions during the solar minimum (2009 - 2010 using the 40.8 MHz coherent backscatter radar at Daejeon (36.18°N, 127.14°E, 26.7°N dip latitude in South Korea. The radar, which consists of 24 Yagi antennas, observes the FAIs using a single beam with a peak power of 24 kW. The radar has been continuously operated since December 2009. Depending on the manner of occurrence of the backscatter echoes, the E-region echoes are largely divided into two types: quasi-periodic (QP and continuous echoes. Our observations show that the QP echoes occur frequently above an altitude of 105 km in the post-sunset period and continuous echoes occur preferentially around an altitude of 105 km in the post-sunrise period. QP echoes appear as striated discrete echoes for a period of about 10 - 20 min. The QP-type echoes occur more frequently than the continuoustype echoes do and the echo intensity of the QP type is stronger than that of the continuous type. In the F region, the FAIs occur at night at an altitude interval of 250 - 450 km. As time proceeds, the occurrence height of the FAIs gradually increases until early in the morning and then decreases. The duration of the F-region FAIs is typically a few hours at night, although, in rare cases, FAIs persist throughout the night or appear even after sunrise. We discuss the similarities and differences of the FAIs observed by the Daejeon radar in comparison with other radar observations.

  17. A identidade territorial enogastronômica como elemento de sustentação turística regional : a experiência do Tirol e Südtirol = Territorial enogastronony identity as a point of regional touristic development : Tyrol and Soul Tyrol experience

    OpenAIRE

    do Nascimento e Silva, Roberto

    2016-01-01

    No que diz respeito ao turismo, percebe-se que, espaços antes isolados, ou então com relações restritas em escala regional, tornam-se partes de um sistema de abrangência global que acaba por sofrer influências da padronização de produtos e da redefinição de territórios. Todavia a enogastronomia busca oportunizar a reação regional através do oferecimento de produtos particulares, impregnados de cultura, em que sociedades reconhecem suas identidades e atraem visitantes para a localidade, fazend...

  18. SU-E-I-48: The Behavior of AEC in Scan Regions Outside the Localizer Radiograph FOV: An In Phantom Study of CT Systems From Four Vendors

    Energy Technology Data Exchange (ETDEWEB)

    Supanich, M [Rush University Medical Center, Chicago, IL (United States); Bevins, N [Henry Ford Health System, Detroit, MI (United States)

    2014-06-01

    Purpose: This review of scanners from 4 major manufacturers examines the clinical impact of performing CT scans that extend into areas of the body that were not acquired in the CT localizer radiograph. Methods: Anthropomorphic chest and abdomen phantoms were positioned together on the tables of CT scanners from 4 different vendors. All of the scanners offered an Automatic Exposure Control (AEC) option with both lateral and axial tube current modulation. A localizer radiograph was taken covering the entire extent of both phantoms and then the scanner's Chest-Abdomen-Pelvis (CAP) study was performed with the clinical AEC settings employed and the scan and reconstruction range extending from the superior portion of the chest phantom through the inferior portion of the abdomen phantom. A new study was then initiated with a localizer radiograph extending the length of the chest phantom (not covering the abdomen phantom). The same CAP protocol and AEC settings were then used to scan and reconstruct the entire length of both phantoms. Scan parameters at specific locations in the abdomen phantom from both studies were investigated using the information contained in the DICOM metadata of the reconstructed images. Results: The AEC systems on all scanners utilized different tube current settings in the abdomen phantom for the scan completed without the full localizer radiograph. The AEC system behavior was also scanner dependent with the default manual tube current, the maximum tube current and the tube current at the last known position observed as outcomes. Conclusion: The behavior of the AEC systems of CT scanners in regions not covered by the localizer radiograph is vendor dependent. To ensure optimal image quality and radiation exposure it is important to include the entire planned scan region in the localizer radiograph.

  19. SU-E-T-570: Management of Radiation Oncology Patients with Cochlear Implant and Other Bionic Devices in the Brain and Head and Neck Regions

    Energy Technology Data Exchange (ETDEWEB)

    Guo, F.Q; Chen, Z; Nath, R [Yale New Haven Hospital, New Haven, CT (United States); Yale UniversitySchool of Medicine, New Haven, CT (United States)

    2014-06-01

    Purpose: To investigate the current status of clinical usage of cochlear implant (CI) and other bionic devices (BD) in the brain and head and neck regions (BH and N) and their management in patients during radiotherapy to ensure patient health and safety as well as optimum radiation delivery. Methods: Literature review was performed with both CIs and radiotherapy and their variants as keywords in PubMed, INSPEC and other sources. The focus was on CIs during radiotherapy, but it also included other BDs in BHȦN, such as auditory brainstem implant, bionic retinal implant, and hearing aids, among others. Results: Interactions between CIs and radiation may cause CIs malfunction. The presence of CIs may also cause suboptimum dose distribution if a treatment plan was not well designed. A few studies were performed for the hearing functions of CIs under irradiations of 4 MV and 6 MV x-rays. However, x-rays with higher energies (10 to 18 MV) broadly used in radiotherapy have not been explored. These higher energetic beams are more damaging to electronics due to strong penetrating power and also due to neutrons generated in the treatment process. Modern CIs are designed with more and more complicated integrated circuits, which may be more susceptible to radiation damage and malfunction. Therefore, careful management is important for safety and treatment outcomes. Conclusion: Although AAPM TG-34, TG-63, and TG-203 (update of TG-34, not published yet) reports may be referenced for management of CIs and other BDs in the brain and H and N regions, a site- and device-specified guideline should be developed for CIs and other BDs. Additional evaluation of CI functions under clinically relevant set-ups should also be performed to provide clinicians with better knowledge in clinical decision making.

  20. SU-E-I-48: The Behavior of AEC in Scan Regions Outside the Localizer Radiograph FOV: An In Phantom Study of CT Systems From Four Vendors

    International Nuclear Information System (INIS)

    Supanich, M; Bevins, N

    2014-01-01

    Purpose: This review of scanners from 4 major manufacturers examines the clinical impact of performing CT scans that extend into areas of the body that were not acquired in the CT localizer radiograph. Methods: Anthropomorphic chest and abdomen phantoms were positioned together on the tables of CT scanners from 4 different vendors. All of the scanners offered an Automatic Exposure Control (AEC) option with both lateral and axial tube current modulation. A localizer radiograph was taken covering the entire extent of both phantoms and then the scanner's Chest-Abdomen-Pelvis (CAP) study was performed with the clinical AEC settings employed and the scan and reconstruction range extending from the superior portion of the chest phantom through the inferior portion of the abdomen phantom. A new study was then initiated with a localizer radiograph extending the length of the chest phantom (not covering the abdomen phantom). The same CAP protocol and AEC settings were then used to scan and reconstruct the entire length of both phantoms. Scan parameters at specific locations in the abdomen phantom from both studies were investigated using the information contained in the DICOM metadata of the reconstructed images. Results: The AEC systems on all scanners utilized different tube current settings in the abdomen phantom for the scan completed without the full localizer radiograph. The AEC system behavior was also scanner dependent with the default manual tube current, the maximum tube current and the tube current at the last known position observed as outcomes. Conclusion: The behavior of the AEC systems of CT scanners in regions not covered by the localizer radiograph is vendor dependent. To ensure optimal image quality and radiation exposure it is important to include the entire planned scan region in the localizer radiograph

  1. Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women

    DEFF Research Database (Denmark)

    Stengård, Jari H; Dyson, Greg; Frikke-Schmidt, Ruth

    2010-01-01

    that acknowledges the complex pathobiology of IHD, we identified a subsample of 764 elderly women (> or =65 years) with hypertriglyceridemia who had a history of smoking, a history of hypertension, or a history of both in which the A(560)T(832)/A(560)T(832) and A(560)T(832)/A(560)G(832) 5' 2-SNP genotypes had...... a higher cumulative incidence of IHD (172/1000) compared to the incidence of 70/1000 in the total sample of women. CONCLUSIONS: Our study validates that 5' apolipoprotein E genotypes improve the prediction of IHD and documents that the improvement is greatest in a subset defined by a particular combination...

  2. Auditoria financeira e a sua importância para os stakeholders na Liga Portuguesa Contra o Cancro-Núcleo Regional do Norte

    OpenAIRE

    Marques, Filipe André da Costa

    2016-01-01

    Nota: 15 valores Na sequência da crise financeira e de valores existentes na sociedade, o Estado não consegue suprir as crescentes desigualdades sociais. As instituições de carácter social aparecem como suporte a esta realidade. Estas sobrevivem de apoios da sociedade civil, sob a forma de donativos, heranças, doações, legados, entre outras. Deste modo, é fundamental que estas Instituições disponham de uma auditoria financeira realizada por entidade independente, uma vez que há a necess...

  3. Identification and analysis of local and regional impacts from the introduction of biodiesel production in the state of Piaui, Brazil; Identificacao e analise dos impactos locais e regionais da introducao da producao de biodiesel no estado do Piaui

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Omar Inacio Benedetti; Rathmann, Regis [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Coordenacao dos Programas de Pos-Graduacao de Engenharia (COPPE). Programa de Planejamento Energetico; Padula, Antonio Domingos [Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, RS (Brazil)

    2008-07-01

    The recent moves towards the insertion of biofuels in the energy matrix of a number of countries are opening new prospects for agricultural production and for agroindustrial chains. This study aims at understanding the mechanisms taking place within a production system geared towards biodiesel production. The emergence of this new productive base raises new research issues: in what circumstances are the structuring, organization and implementation of these biodiesel productive chains taking place in Brazil? What are the effects of biodiesel production on local economies? Hence, the central objective of this study is the development and validation of an analytical structure capable of characterizing the biodiesel productive arrangements and identifying their economic and social impacts at the regions where they are installed. A preliminary analysis identified that a biodiesel productive arrangement is emerging in the State of Piaui, Northeastern Brazil, Our theoretical basis comprises elements from the regional economy, biorefineries, local production arrangements and innovation. For the analyses, we employed the methods of input-output, local quotient and shift-share. It can be said that a new social-economic dynamics is taking place in Piaui; however, the company needs to assess its interaction with local institutions as well as its castor bean production strategies. (author)

  4. La Macroregione Adriatico-Ionica: passato e presente – Eventi, problematiche e testimonianze, per costruire un futuro migliore (The Adriatic-Ionian Macro-Region, Past and Present, Events, Problems and Witness for the Construction of a Better Future

    Directory of Open Access Journals (Sweden)

    Simona Paula DOBRESCU

    2016-09-01

    Full Text Available he Adriatic-Ionian region (EUSAIR covers an outstanding area of maritime countries, of which four are member states of the European Union (Italy, Slovenia, Croatia and Greece and four non-members (Albania, Serbia, Montenegro and Bosnia-Herzegovina. It is a crossroad meeting place of peoples, religions and cultures that are often at loggerheads, sometimes on speaking terms. Religion has contributed to widening the division. However, in the last decades progress has been made towards an inter-religious dialogue. The lessons of the remote past and recent times have brought home the need to strengthen relations, to extend friendship, to prepare to defend the common values of liberty, peace and justice. The problems in the Balkans, but also those world-wide, need a positive and coherent approach. Prosperity, security and harmony of the various ethnic- religious components in the macro-region must develop peacefully. Unfortunately, the threat of war and hatred are destabilizing many parts of the world and every religion is called upon to defend peace. It is time for the individual illuminated voices to be supported by the body of the people of God, that is, God, the common father of all men who has given humanity the great gift of choosing between Good and Evil.

  5. Reestruturação urbano-Regional em São Paulo: falácias e fantasias do apocalipse industrial metropolitano

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    Rogério dos Santos Acca

    2003-01-01

    Full Text Available Este artigo busca discutir com a literatura recentemente produzida para dar conta dos padrões de reestruturação urbano-industrial em São Paulo. Entendendo as metrópoles como espaços de produção pós-industrial, a literatura sobre as cidades globais observa uma tendência de crescimento vertiginoso do setor de serviços na esteira da intensificação do papel do capital financeiro como elemento dinâmico basilar de uma nova economia. Assim, as cidades globais centralizariam os grandes conglomerados do setor financeiro que se tornam extremamente dependentes da infra-estrutura, da mão-de-obra altamente especializada e da disponibilidade de informações presentes nos grandes centros urbanos. Nesse sentido, o setor de serviços - dinamizado pelo setor financeiro, basicamente - tenderia a superar a indústria em termos de geração de dinamismo econômico e social nos conglomerados urbanos. Contudo, os padrões recentes da produção metropolitana paulista indicam que a indústria continua sendo o elemento central na dinâmica territorial da RMSP, evidenciando que estamos distantes de um apocalipse da indústria, possibilitado pelo deslocamento dos setores-chave da economia.

  6. Espaço, cidades e escalas territoriais: novas implicações de políticas de desenvolvimento regional

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    Ana Carolina da Cruz Lima

    2014-04-01

    Full Text Available O papel do espaço no processo de desenvolvimento socioeconômico constitui um objeto de estudo bastante complexo. Os teóricos da Escola Francesa de Sociologia Urbana elaboraram uma série de estudos nesta área com o intuito de esclarecer as relações entre a forma espacial e os processos sociais. O objetivo do artigo é destacar os principais argumentos desta Escola de Pensamento, o papel desempenhado pelas cidades neste processo e as principais recomendações de políticas de desenvolvimento que surgem a partir de então. A análise sugere que as escalas territoriais tornam-se fundamentais para a dinâmica das economias nacionais, o que lhes concede papel de destaque como objeto de política: medidas intervencionistas devem ser combinadas nas diversas escalas territoriais, considerando a localidade como parte do todo. É preciso repensar a espacialidade, o que contribuirá para o desenvolvimento socioeconômico integrado.

  7. Biomassa microbiana e atividade enzimática em solos sob vegetação nativa e sistemas agrícolas anuais e perenes na região de Primavera do Leste (MT Microbial biomass and enzyme activities in soils under native vegetation and under annual and perennial cropping systems at the Primavera do Leste region - Mato Grosso State

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    M. Matsuoka

    2003-06-01

    Full Text Available Primavera do Leste é um dos pólos de produção de grãos e fibras do M