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Sample records for dyssomnias

  1. 缺血性脑卒中后睡眠障碍患者的多导睡眠图分析%Analysis of polysomnography in patients with post-ischemic stroke dyssomnia

    Institute of Scientific and Technical Information of China (English)

    李婷; 史丽娜; 范学文

    2015-01-01

    Objective:To investigate the sleep process and sleep structure of patients with post -ischemic stroke dyssomnia and the types of post-stroke dyssomnia, so as to provide the basis for the treatment of this disease.Methods:The whole night polosomnography(PSG) of 58 pa-tients of post-ischemic stroke dyssomnia and 42 normal subjects were monitored with PSG instruments .Results:The poloysomnography of patients with post-ischemic stroke dyssomnia showed prolonged sleep latency(SL), decreased total sleep duration (TST) , low sleep efficiency(SE %), increased light sleep (S1), decreased rapid eye movement (REM) and increased waking frequency.About 53% of patients were recorded as SRBD, among which one was REM sleep behavior disorder ( RBD) .Compared with the control group, TST、SE and REM in patients with post-ischemic stroke dyssomnia were significantly reduced ( P <0.05), and SL and S1 in them were significantly increased ( P <0.05).Conclu-sions:There are significant changes in the sleep process and sleep structure of patients with post -ischemic stroke dyssomnia, who are predisposed to complicate SRBD and RBD.The application of PSG in correctly assessing sleep quality and sleep type can improve these patients'prognosis.%目的:研究缺血性脑卒中后睡眠障碍患者的睡眠进程及睡眠结构,了解卒中后睡眠障碍的类型,为卒中后睡眠障碍的治疗提供依据。方法:应用多导睡眠监测仪对58例缺血性卒中后睡眠障碍患者及42例健康人进行整夜多导睡眠图( poly somnogram,PSG)监测。结果:缺血性脑卒中睡眠障碍患者PSG表现为睡眠潜伏期(sleep latency,SL)延长,总睡眠时间(total sleep time,TST)缩短,睡眠效率(sleep efficiency,SE%)低,浅睡眠(light sleep,S1)增多,快速动眼睡眠期(rapid eye movement,REM期)减少,觉醒(wake after sleep onset, WASO)次数及时间增多。约53%患者表

  2. Heat rate variability and dyssomnia and their correlations to neurological defects in cerebral infarction patients complicated by insomnia A concurrent non-randomized case-control study

    Institute of Scientific and Technical Information of China (English)

    Jianping Chu; Xueli Shen; Jun Fan; Changhai Chen; Shuyang Lin

    2008-01-01

    cerebral infarction patients with insomnia, the Pittsburgh Sleep Quality Index score was significantly positively correlated with neurological impairment (r = 0.54, P < 0.01). The low-frequency band, very low-frequency band, high-frequency band, R-R interval variance, total power, R-R interval, and the percentage of high-frequency were significantly negatively cor-related with the National Institutes of Health Stroke Scale score (r =–0.45 to –0.90, P < 0.05–0.01) and with the Pittsburgh Sleep Quality Index scores (r = –0.56 to –0.36, P < 0.05–0.01). CONCLUSION: Each heart rate variability parameter can be used as an index for assessing dyssomnia and neurologic impairment (r =–0.56 to –0.36, P < 0.05–0.01).

  3. Observations on the Therapeutic Effect of Acupuncture on Dyssomnia in Children with Mental Retardation%针刺治疗智力低下儿童睡眠障碍疗效观察

    Institute of Scientific and Technical Information of China (English)

    曾懿懿; 黄任秀; 邓梁琼; 刘芳坚

    2015-01-01

    目的:观察针刺治疗智力低下患者睡眠障碍的临床疗效。方法将60例智力低下患者(4~6岁)随机分为治疗组和对照组,每组30例。对照组采用常规康复治疗(指导家庭训练同时进行病因心理行为干预),治疗组在对照组治疗基础上采用针刺治疗。治疗12星期后,采用多导睡眠图监测两组患者睡眠潜伏期、快动眼睡眠状态(REM)、睡眠效率,并比较两组临床疗效。结果治疗组总有效率为93.3%,对照组为73.3%,两组比较差异具有统计学意义(P<0.05)。两组治疗后睡眠潜伏期、REM及睡眠效率与同组治疗前比较,差异均具有统计学意义(P<0.05)。治疗组治疗前后睡眠潜伏期、REM及睡眠效率差值与对照组比较,差异均具有统计学意义(P<0.05)。结论针刺是一种治疗智力低下患者睡眠障碍的有效方法。%Objective To investigate the clinical efficacy of acupuncture in treating dyssomnia in children with mental retardation. Methods Sixty patients with mental retardation (4-6 years old) were randomly allocated to treatment and control groups, 30 cases each. The control group received routine rehabilitation therapy (family training guidance, and aetiological, psychological and behavioral intervention) and the treatment group, acupuncture in addition. Sleep latency, rapid eye movement (REM) sleep state and sleep efficiency were monitored by polysomnography in the two groups of patients. The clinical therapeutic effects were compared between the two groups. Results The total efficacy rate was 93.3%in the treatment group and 73.3%in the control group;there was a statistically significant difference between the two groups (P<0.05). There were statistically significant differences in pre-/post-treatment sleep latency, REM sleep state and sleep efficiency difference values between the treatment and control groups (P<0.05). Conclusion Acupuncture is an effective way to treat dyssomnia in

  4. 老年高血压患者睡眠不良原因分析及针对性护理干预效果观察%Dyssomnias analysis of elderly hypertensive patients and effects of reason-directed nurse care

    Institute of Scientific and Technical Information of China (English)

    冯金葵; 汪峰

    2012-01-01

    Objective To evaluate the factors influencing the sleep quality of elderly hypertensive patients and to explore the effects of reason-directed nurse care on sleep quality and blood pressure. Methods Questionnaire was used to investigate the factors of dyssomnias of elderly hypertensive patients and Pittsburgh Sleep QuMity Index (PSQI) was used to evaluate the sleep quality. The factors of dyssomnias were analyzed and sleep quality and blood pressure changes before and after nurse care were compared. Results Dyssomnias was found in 55.7% of all cases. After dyssomnias factor analysis, 26 cases (66.7%) had the factors of mind and mood. In addition, 26 cases (66.7%) had pathology factors; 10 cases (25.6%) had environment factors; 9 cases (23.1%) had habit factors; 2 cases (5.1%) had the drug factors. After reason-directed nurse care, average PSQI score of dyssomnias patients was decreased. Moreover, systolic pressure and diastolic pressure were dropped from (173.86± 17.93) mmHg and (107.35± 13.55) mmHg to (149.67±15.45) mmHg and (88.75±11.68) mmHg, respectively (P<0.01). Conclusion Reason-directed nurse care can improve the sleep quality and treatment effect for elderly hypertensive patients.%目的 了解影响老年高血压患者睡眠质量的因素,探讨针对性护理干预对改善睡眠质量和控制血压的作用.方法 对在本院保健科就诊的老年高血压患者70例进行问卷调查并用匹兹堡睡眠质量指数(PSQI)评价睡眠质量.分析睡眠不良的原因并采用针对性护理干预,比较护理干预前后患者睡眠改善情况和血压变化.结果 55.7%的老年高血压患者存在睡眠不良.导致睡眠不良的原因中,精神情绪因素26例,占66.7%;其他依次为病理因素(17例,43.6%)、环境因素(10例,25.6%)、生活习惯因素(9例,23.1%)和药物因素(2例,5.1%).针对性护理干预后,睡眠不良患者PSQI评分下降,收缩压及舒张压分别从(173.86±17.93)mmHg和(107.35±13

  5. Perioperative Outcome of Dyssomnia Patients on Chronic Methylphenidate Use

    OpenAIRE

    Nicoleta Stoicea MD, PhD; Thomas Ellis MD; Kenneth Moran MD; Wiebke Ackermann MD; Thomas Wilson; Eduardo Quevedo MD; Sergio Bergese MD

    2014-01-01

    Methylphenidate is frequently prescribed for attention deficit hyperactivity disorder, narcolepsy, and other sleep disorders requiring psychostimulants. Our report is based on 2 different clinical experiences of patients with chronic methylphenidate use, undergoing general anesthesia. These cases contrast different strategies of taking versus withholding the drug treatment on the day of surgery. From the standpoint of anesthetic management and patient safety, the concerns for perioperative me...

  6. Perioperative Outcome of Dyssomnia Patients on Chronic Methylphenidate Use

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    Nicoleta Stoicea MD, PhD

    2014-01-01

    Full Text Available Methylphenidate is frequently prescribed for attention deficit hyperactivity disorder, narcolepsy, and other sleep disorders requiring psychostimulants. Our report is based on 2 different clinical experiences of patients with chronic methylphenidate use, undergoing general anesthesia. These cases contrast different strategies of taking versus withholding the drug treatment on the day of surgery. From the standpoint of anesthetic management and patient safety, the concerns for perioperative methylphenidate use are mainly related to cardiovascular stability and possible counteraction of sedatives and anesthetics.

  7. The observation of Tiapride curative effect on 60 mental disorder patients with anxiety and dyssomnia%泰必利治疗神经症患者焦虑及睡眠障碍 60例疗效观察

    Institute of Scientific and Technical Information of China (English)

    李文华; 苏建宁; 龚劭工

    2001-01-01

    @@Background:Tiapride is a kind of derivative with thiamphenicol and o- dianisidine. It mainly acts on mesencephalon limbic system, blocks dopamine receptor selectively, it also has antagonism on corpus striatum dopamine somatic abnormal. Thus the patients are made tranquilizer, calm and pain relieved. Generally it has a certain curative effect on mental disorder people. Objective:To discuss the curative effect of mental disorder people, and to find on which symptom it has the best curative effect.

  8. 低能量氦-氖激光血管内照射治疗老年人睡眠障碍26例%26 Cases of Senile Dyssomnia Treated by Low Energy Helium-neon Laser Irradiation into Blood Vessel

    Institute of Scientific and Technical Information of China (English)

    林丽珍

    2003-01-01

    @@ 老年人睡眠障碍是加速衰老并直接影响健康的常见病症,药物对症治疗效果多不满意[1].我科采用单盲法观察了低能量氦-氖激光血管内照射治疗老年人睡眠障碍取得了一定效果,现报告如下.

  9. Clinical Observation on Acupuncture Treatment of Depressive Neurosis in 30 Cases

    Institute of Scientific and Technical Information of China (English)

    Zhao Jiahui; Sang Peng

    2006-01-01

    @@ Depressive neurosis refers to a psychonosema disease,characterized by emotional depression with anxiety and dyssomnia. Usually antidepressants are used for this disease. However, they are slow in giving effects with more side-effects. The authors of this essay have adopted acupuncture for the treatment, and obtained good therapeutic results as reported in the following.

  10. 听觉耐受下降与耳鸣%Decreased sound tolerance and tinnitus

    Institute of Scientific and Technical Information of China (English)

    祝晓宇; 张剑宁; 李明

    2012-01-01

    Summary Decreased sound tolerance includes hyperacusis and/or misophonia (phonophobia). As a commonly subjective symptom, tinnitus is defined to be a sound perceived in the ear or head without corresponding sound or electrical stimulus in the surrounding environment. It is usually occured with or without hearing loss or harmful psychic reaction, which includes dyssomnia, annoy, rage, anxiety, depress, hard to concentrate, etc. Frequently, tinnitus is accompied by decreased sound tolerance, while this text is aimed to review the corelated concepts of decreased sound tolerance,and focus on the hyperacusis which is a more common symptom.

  11. Comparison of Sleep Disorder in Myocardial Infarction Patients with Their Healthy Relatives

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    AR Javan

    2007-10-01

    Full Text Available Introduction & Objective: Cardiovascular diseases are among the most common causes of mortality and sleep disturbances are common in today society. The purpose of the present study is to determine relationship between wide spectrum of sleep disorders including dyssomnias and parasomnias and occurrence of myocardial infarction. Materials & Methods: This is a prospective case control study which was performed on 65 patients with acute myocardial infarction and 65 cases of their healthy relatives. Data were collected by Epworth sleepiness scale and analyzed with SPSS software and using chi square, t-test and variance analysis. Results: For dyssomnias, frequency of early awakening in the morning, sleep duration at night, difficulty in falling asleep, sleep disruption and restless leg syndrome in case group were significantly higher than control group. For parasomnias, frequency of sleep paralysis, nightmare and sleep walking in case group were significantly higher than control group. Conclusion: Sleep disorders are more frequent among patients with myocardial infraction and can be considered as a risk factor for this disorder.

  12. Sleep problems in primary school children: comparison between mainstream and special school children.

    Science.gov (United States)

    Quine, L

    2001-05-01

    This paper reports on a study of the prevalence and social correlates of dyssomnias, features associated with obstructive sleep apnoea, and parasomnias in primary school children aged 4-12. Head teachers of schools selected randomly from lists of local primary and special schools were contacted by telephone and asked to distribute a questionnaire package to the parents of all pupils aged 4-12 years. In all, 890 parents of children from mainstream schools and 300 from special schools were approached. The response rates were 64.7% and 60%, respectively. The results showed that significantly higher proportions of children in special schools than in mainstream schools presented four of the five dyssomnias investigated and all of the features associated with obstructive sleep apnoea. In contrast, only two of the seven parasomnias were presented by higher proportions of the children in special schools. Age and gender differences for the two groups of children are presented. Finally, multiple correlations were computed between a range of child, family, and environmental characteristics and the three problems most frequently reported: frequency of settling problems; sleeping in the parents' bed; and night waking. The findings are discussed with reference to other studies of children's sleep problems, and the implications for treatment are considered.

  13. Structure of comorbid psychopathological disorders in patients with type 2nd diabetes mellitus

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    V. V. Chugunov

    2017-04-01

    Full Text Available Aim: to identify and explore the structure of comorbid psychopathological disorders in patients with type 2nd diabetes mellitus (DM. Materials and methods: 543 patients with type 2nd DM were included into the study. The average age of patients was (56.2 ± 0.65 years. The patients were divided into three groups according to the severity of DM. The first clinical group (CG-1 included 57 patients with type 2nd DM of mild severity, who was treated in outpatient department; the average age in the group was (51.8 ± 1.28 years. The second clinical group (CG-2 made up of 312 patients with type 2nd DM, moderate severity, they were in inpatient department; the median age of the group was (55.1 ± 1.12 years. The third clinical group (CG-3 included 174 patients with type 2nd DM, severe degrees of severity, they undergone inpatient treatment too; average age in the group was (61.8 ± 0.85 years. Research methods: clinical-anamnesis, clinical- psychopathological, statistical. Research results. The study established the incidence of non-psychotic mental disorders of varying severity in patients with type 2nd DM at the level of 94.11 %, among them, for 91.16 % – of psychogenic origin. Proportional correlation between the severity of type 2nd DM and the absence of comorbid psychopathological manifestations was detected (rs = -0.3416, p < 0.01. It is revealed that the dominant psychopathological syndromes among all patients with type 2nd DM were psychoorganic (62.43 %, dyssomnia (60.86 %, asthenic (55.58 % and anxiety (43.05 % syndromes. Structure of the dominant psychopathological syndromes was established depending on severity of type 2nd DM: in CG-1 dominated dyssomnia (36.84 %, anxiety (31.58 %, psychoorganic (21.05 % syndromes; in CG-2 – psychoorganic (65.38 %, asthenic (40.38 %, dyssomnia (38.46 %, anxiety (37, and 82 % syndromes; in CG-3 – dyssomnia (97.70 %, asthenic (89.08 %, organic mental (70.69 %, anxious 48.28 % syndromes. Significant

  14. 发作性睡眠障碍

    Institute of Scientific and Technical Information of China (English)

    王德生; 王晔

    2004-01-01

    国际睡眠疾病分类将睡眠障碍分为4类:睡眠失调(dyssomnia)、异态睡眠(parasomnia)、器质性或精神病性睡眠疾病和建议的睡眠疾病。与睡眠相关的神经系统疾病包括痴呆、神经变性病、帕金森综合征、家族性致死性失眠症、睡眠相关性癫疴、睡眠癫疴放电状态、睡眠相关性头痛。异态睡眠为睡眠中发生的主要是自主神经和骨骼肌活动,是

  15. The nocturnal panic attacks: polysomnographic features and comorbidities

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    LI Yan-lin

    2013-05-01

    Full Text Available Background Panic disorder refers to the repeated or unexpected anxiety or panic attacks. It makes patients feel extreme pain. Although the episodes of most patients with panic disorder happen at daytime, the nocturnal panic attacks (NPA are quite common. Paients pay more attention to NPA. Insomnia is more serious in patients with NPA than those patients with panic disorder attack at daytime. Many patients may occur anxiety and avoidance behavior after NPA. Patients are often afraid of sleeping, or even do not sleep. The aim of this study is to analyze polysomnographic (PSG parameter changes and clinical concomitant symptoms of patietns with NPA, to explore the characteristics of sleep, in order to provide better diagnosis, differential diagnosis and treatment for these patients. Methods The features of sleep of 20 NPA patients and 23 healthy controls were monitored by video-PSG. Hamilton Anxiety Rating Scale (HAMA and Hamilton Depression Rating Scale (HAMD were used to assess the state of anxiety, depression, and dyssomnia of the patients. Results In comparison with normal control group, the NPA group showed shortened total sleep time (TST, decreased sleep efficiency (SE and sleep maintenance rate, delayed arousal time, increased number of arousal and number of arousal episode longer than 5 minutes, increased percentage of non-rapid eye movement (NREM sleep stage Ⅰ, decreased percentage of NREM sleep stageⅢ and percentage of rapid eye movement (REM sleep (P 0.05, for all. In NPA group, there were 13 cases (13/20 with anxiety, 17 (17/20 with depression, 13 cases/times (13/20 with difficulty of falling asleep, 17 cases/times (17/20 with difficulties in maintaining sleep (frequent arousals and difficult to fall asleep again and 7 cases/times (7/20 with wake up early. Conclusion NPA patients present decreased deep sleep, increased shallow sleep and poor sleep quality, and are mostly accompanied with mild or moderate depression and (or anxiety

  16. Clinical Uses of Melatonin in Pediatrics

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    Emilio J. Sánchez-Barceló

    2011-01-01

    Full Text Available This study analyzes the results of clinical trials of treatments with melatonin conducted in children, mostly focused on sleep disorders of different origin. Melatonin is beneficial not only in the treatment of dyssomnias, especially delayed sleep phase syndrome, but also on sleep disorders present in children with attention-deficit hyperactivity, autism spectrum disorders, and, in general, in all sleep disturbances associated with mental, neurologic, or other medical disorders. Sedative properties of melatonin have been used in diagnostic situations requiring sedation or as a premedicant in children undergoing anesthetic procedures. Epilepsy and febrile seizures are also susceptible to treatment with melatonin, alone or associated with conventional antiepileptic drugs. Melatonin has been also used to prevent the progression in some cases of adolescent idiopathic scoliosis. In newborns, and particularly those delivered preterm, melatonin has been used to reduce oxidative stress associated with sepsis, asphyxia, respiratory distress, or surgical stress. Finally, the administration of melatonin, melatonin analogues, or melatonin precursors to the infants through the breast-feeding, or by milk formula adapted for day and night, improves their nocturnal sleep. Side effects of melatonin treatments in children have not been reported. Although the above-described results are promising, specific studies to resolve the problem of dosage, formulations, and length of treatment are necessary.

  17. Sleep problems and internet addiction among children and adolescents: a longitudinal study.

    Science.gov (United States)

    Chen, Yi-Lung; Gau, Susan Shur-Fen

    2016-08-01

    Although the literature has documented associations between sleep problems and internet addiction, the temporal direction of these relationships has not been established. The purpose of this study is to evaluate the bidirectional relationships between sleep problems and internet addiction among children and adolescents longitudinally. A four-wave longitudinal study was conducted with 1253 children and adolescents in grades 3, 5 and 8 from March 2013 to January 2014. The sleep problems of the student participants were measured by parental reports on the Sleep Habit Questionnaire, which catalogues early insomnia, middle insomnia, disturbed circadian rhythm, periodic leg movements, sleep terrors, sleepwalking, sleep talking, nightmares, bruxism, snoring and sleep apnoea. The severity of internet addiction was measured by students' self-reports on the Chen Internet Addiction Scale. Based on the results of time-lag models, dyssomnias (odds ratio = 1.31), especially early and middle insomnias (odds ratio = 1.74 and 2.24), sequentially predicted internet addiction, and internet addiction sequentially predicted disturbed circadian rhythm (odds ratio = 2.40), regardless of adjustment for gender and age. This is the first study to demonstrate the temporal relationship of early and middle insomnia predicting internet addiction, which subsequently predicts disturbed circadian rhythm. These findings imply that treatment strategies for sleep problems and internet addiction should vary according to the order of their occurrence.

  18. Functional neuroimaging of sleep.

    Science.gov (United States)

    Nofzinger, Eric A

    2005-03-01

    Sleep and sleep disorders have traditionally been viewed from a polysomnographic perspective. Although these methods provide information on the timing of various stages of sleep and wakefulness, they do not provide information regarding function in brain structures that have been implicated in the generation of sleep and that may be abnormal in different sleep disorders. Functional neuroimaging methods provide information regarding changes in brain function across the sleep-wake cycle that provides information for models of sleep dysregulation in a variety of sleep disorders. Early studies show reliable increases in function in limbic and anterior paralimbic cortex in rapid eye movement (REM) sleep and decreases in function in higher-order cortical regions in known thalamocortical networks during non-REM sleep. Although most of the early work in this area has been devoted to the study of normal sleep mechanisms, a collection of studies in diverse sleep disorders such as sleep deprivation, depression, insomnia, dyssomnias, narcolepsy, and sleep apnea suggest that functional neuroimaging methods have the potential to clarify the pathophysiology of sleep disorders and to guide treatment strategies.

  19. 组织工程修复肩袖损伤促进腱骨愈合的研究进展%Progress in tissue-engineering for tendon-to-bone healing after rotator cuff repair

    Institute of Scientific and Technical Information of China (English)

    赵晨; 王蕾

    2015-01-01

    Rotator cuff injury, considered as a resource of pain, disability and dyssomnia to serious decline in the quality of life, is a common disorder of the shoulder joint. Basic principles of rotator cuff repair aim at achieving high initial ifxation strength, maintaining mechanical stability and restoring the anatomic healing of the cuff tendon. After the routine surgical procedure for rotator cuff repair, the biology and histology of the normal enthesis are not restored. Tendon-to-bone healing occurs with a ifbrovascular scar tissue interface that is mechanically inferior to the native insertion site, which may lead to high re-rupture rate. For these reasons, new approaches are required to improve structural healing. Tissue engineering strategies have been suggested to improve the biological environment around the bone-tendon interface and to promote regeneration of the native insertion site. Although experimental applications of growth factors and scaffolds on animal models demonstrate promising results, techniques which can be used in human rotator cuff repair are still very limited. Tissue engineering to improve tendon-to-bone healing has bright future and requires more research before its clinical applications. This review will outline therapies of growth factors, scaffolds and stem cells in tendon healing and rotator cuff repair.

  20. Hypocalcemia and Hypomagnesemia in Perioperative Period of Congenital Hypertrophic Pyloric Stenosis%先天性肥厚性幽门狭窄围手术期低钙低镁血症

    Institute of Scientific and Technical Information of China (English)

    傅红茹; 连贵新; 李新房

    1994-01-01

    32例肥厚性幽门狭窄患儿,因长期大量呕吐、摄入不足及吸收障碍等原因,均有不同程度的低钙、低镁血症,其中低钙24例,低镁18例,钙、镁均低者16例.临床表现为易惊、睡眠不安、夜哭、四肢震颤、头向后仰、背肌紧张、面部抽搐,严重者出现喉痉挛.经使用钙、镁制剂后得到控制.%Because of persistent vomiting,inadequate intake and malabsorption,32 cases of pyloric stenosis had vari ous degrees of hypocalcemia and hypomagnesemia.Of them,hypocalcemia was in 24,hypomagnesemia was in 18,and hypocalcemia and hypomagnesemia were in 16.The presentation was to be frightened easily,dyssomnia,night crying,tremor,hypsokinesis and facial of glottic spasm.With the application of pharmaceutical calcium and magnesium,the symptom has been under control.

  1. [Bibliometrics analysis on researches of illness spectrum for acu-moxibustion therapy and prospect].

    Science.gov (United States)

    Yang, Ming-Xiao; Zhao, Ling; Yang, Jie; Cao, Xin-Xin; Yu, Zu-Nian; Liang, Fan-Rong

    2014-06-01

    The research on indications of acu-moxibustion is very important for effectively guiding clinical practice. In the present paper, the authors retrieved domestic literature about researches on the disease-spectrum or indications of acu-moxibustion therapy in recent 10 years, and made a bibliometrics analysis according to the described research methods, publishing year, quantity and their proportionate relationship. A total of 18 qualified original papers involving 414 illnesses or clinical conditions were included in the present paper. Among the 414 kinds of clinical conditions or illnesses, 72 were considered to be suitable candidates for acu-moxibustion therapy, including functional dyspepsia, herpes zoster, irritable bowel syndrome, gastrointestinal dysfunction, scapulohumeral periarthritis, cervical syndrome, dyssomnia, acne (cyst type), chronic urticaria, regional neurodermatitis, pain, itching, etc. which belong to illness-spectrum grade-I. Generally, the acu-moxibustion therapy is, in clinical effects, relatively poorer for structural diseases which are attributed to grade-II or grade-III type. Nevertheless, the diversity of clinical indications of acu-moxibustion has been confirmed nowadays. Current studies on illness-spectrum are of certain uniformity and comprehensiveness, but need further extending and perfecting, and need more standardized methods corresponding to principles of the evidence-based medicine.

  2. Magnitude and influencing factors of parasomnia in schoolchildren

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    Choudhury Habibur Rasul

    2013-11-01

    Full Text Available Background Parasomnias are undesirable events occurring in the sleep-wake transition period. Several predisposing factors are reported to induce parasomnia in preschool children. Objective To estimate the magnitude of parasomnia in school children and to evaluate its relationship with possible predisposing factors. Methods Five hundred children aged 5-16 years from a boys’ school and a girls’ school in Khulna City, Bangladesh, were randomly selected for the study conducted from July to December 2011. The survey was done in two steps: self-administered questionnaire and clinical interviews of affected students and their parents. Apart from demographic features, questionnaires included details of perinatal and personal factors as well as familial and socioeconomic factors. The diagnoses of variants of parasomnias was based on the criteria for category-based classification by the American Academy of Sleep Mmedicine. Results Seven hundred thirteen filled questionnaires revealed parasomnia in 187 (26.2% children. Most parasomnias were accompanied by other sleep disorders, in which 23 (12.3% having primary dyssomnias including 18 (9.3% obstructive sleep apnea, and 10 (5.3% parasomnias with hypersomnias. Nightmares (7.4% were highest among the parasomnias followed by nocturnal enuresis (4.1% and sleep terrors (3.4%. More girls experienced parasomnias than boys (107/360 vs. 80/353, respectively; P=0.039. Perinatal factors such as problems during pregnancy (17.1% or eventful delivery (25.7%, and socioeconomic factors such as familial disharmony (11.8% and low socioeconomic level (31.6% had positive associations with parasomnia. Conclusion One-quarter of school children experience parasomnia. We found perinatal factors particularly problem during pregnancy, and socioeconomic factors particularly familial disharmony have significant influences on this condition. [Paediatr Indones. 2013;53:339-45.].

  3. Lucid Dreaming in Narcolepsy

    Science.gov (United States)

    Dodet, Pauline; Chavez, Mario; Leu-Semenescu, Smaranda; Golmard, Jean-Louis; Arnulf, Isabelle

    2015-01-01

    Objective: To evaluate the frequency, determinants and sleep characteristics of lucid dreaming in narcolepsy Settings: University hospital sleep disorder unit Design: Case-control study Participants: Consecutive patients with narcolepsy and healthy controls Methods: Participants were interviewed regarding the frequency and determinants of lucid dreaming. Twelve narcolepsy patients and 5 controls who self-identified as frequent lucid dreamers underwent nighttime and daytime sleep monitoring after being given instructions regarding how to give an eye signal when lucid. Results: Compared to 53 healthy controls, the 53 narcolepsy patients reported more frequent dream recall, nightmares and recurrent dreams. Lucid dreaming was achieved by 77.4% of narcoleptic patients and 49.1% of controls (P sleep paralysis, dyssomnia, HLA positivity, and the severity of sleepiness were similar in narcolepsy with and without lucid dreaming. Seven of 12 narcoleptic (and 0 non-narcoleptic) lucid dreamers achieved lucid REM sleep across a total of 33 naps, including 14 episodes with eye signal. The delta power in the electrode average, in delta, theta, and alpha powers in C4, and coherences between frontal electrodes were lower in lucid than non-lucid REM sleep in spectral EEG analysis. The duration of REM sleep was longer, the REM sleep onset latency tended to be shorter, and the percentage of atonia tended to be higher in lucid vs. non-lucid REM sleep; the arousal index and REM density and amplitude were unchanged. Conclusion: Narcoleptics have a high propensity for lucid dreaming without differing in REM sleep characteristics from people without narcolepsy. This suggests narcolepsy patients may provide useful information in future studies on the nature of lucid dreaming. Citation: Dodet P, Chavez M, Leu-Semenescu S, Golmard JL, Arnulf I. Lucid dreaming in narcolepsy. SLEEP 2015;38(3):487–497. PMID:25348131

  4. Survey and analysis on postoperative sleep quality and influencing factors for orthopedics patients%骨科患者术后睡眠质量及影响因素的调查与分析

    Institute of Scientific and Technical Information of China (English)

    王爱平; 梅卫婷; 王桂平

    2012-01-01

    Objective To observe the postoperative sleep quality and influencing factors for orthopedics patients. Method Investigate 350 patients by Pittsburgh Sleep Quality Index (PSQI) and self-designed questionnaire on risking factors of sleep quality. Analyze the underlying factors by Logistic regression model. Result The average score of PSQI is (8. 38 + 3. 52). 57. 4% patients suffering from dyssomnia. Risking factors of sleep quality arc pain, compulsive position, concern on prognosis, economic burden, noise in wards and change in living habits. Conclusion Orthopedics patients have poor sleep quality. Countermcasurcs on nursing should be taken to improve their sleep quality.%目的 调查骨科患者术后的睡眠质量及影响因素.方法 采用匹兹堡睡眠质量指数量表和自制的影响睡眠因素调查表,对350例患者进行问卷调查,对潜在影响因素应用Logistic 回归模型进行分析.结果 患者匹兹堡睡眠质量指数平均得分(8.38±3.52)分,57.4%患者睡眠不良,影响睡眠的因素分别为疼痛、被迫体位、担心预后、经济负担、病房噪声、生活习惯改变.结论 骨科患者术后睡眠质量差,需采取相应护理对策,改善患者睡眠质量.

  5. 不同养生功法对2型糖尿病伴失眠患者睡眠质量的影响%Influences of different qigong practices on sleep quality in patients with type 2 diabetes accompanied by insomnia

    Institute of Scientific and Technical Information of China (English)

    王芳; 岸太一; 辻内琢也; 铃木晶夫; 春木丰; 汪卫东; 张容瑞; 林颖娜; 洪兰; 赵阳; 倪青; 石井康智; 越川房子

    2009-01-01

    Qigong. The Pittsburgh Sleep Quality Index (PSQI) was used to detect the sleep quality, and the actual time to fall asleep and actual sleep time were recorded in all patients before treatment and 2 months and 4 months after treatment respectively. The data obtained were analyzed statistically by SPSS statistical software. Results There were 78 patients enclosed in the analysis and the expulsion rate was 13.3%. After 4 months the comparison among groups showed that the total score of PSQI, factor of subjective sleep quality and factor of dyssomnia were higher significantly in group 1 than those in group 3 (P<0.05). The comparison in difference among groups showed that the factor of subjective sleep quality was higher in group 1 and 2 than that in group 3 (P<0.05), while the total score of PSQI and factor of dyssomnia were higher in group 1 than those in group 3 (P<0.05). The comparison within a group showed that the total score of PSQI and other five factors, except the factor of sleep time, were promoted significantly in group 1 (P<0.05). The total score of PSQI and other four factors, except the factor of sleep time and dyssomnia, were promoted significantly in group 2 (P<0.05). The actual time to fall asleep and actual sleep time were improved significantly in group 1 and 2 (P<0.05). Conclusion The Health Preserving Qigong of TCM can improve the sleep quality in the patients with type 2 diabetes accompanied by insomnia. Baduanjin Qigong is different from Liuzijue Qigong in practice methods, and their effects are different too after combined with Relaxation Qigong.

  6. Ambient Light Intensity, Actigraphy, Sleep and Respiration, Circadian Temperature and Melatonin Rhythms and Daytime Performance of Crew Members During Space Flight on STS-90 and STS-95 Missions

    Science.gov (United States)

    Czeisler, Charles A.; Dijk, D.-J.; Neri, D. F.; Hughes, R. J.; Ronda, J. M.; Wyatt, J. K.; West, J. B.; Prisk, G. K.; Elliott, A. R.; Young, L. R.

    1999-01-01

    Sleep disruption and associated waking sleepiness and fatigue are common during space flight. A survey of 58 crew members from nine space shuttle missions revealed that most suffered from sleep disruption, and reportedly slept an average of only 6.1 hours per day of flight as compared to an average of 7.9 hours per day on the ground. Nineteen percent of crewmembers on single shift missions and 50 percent of the crewmembers in dual shift operations reported sleeping pill usage (benzodiazepines) during their missions. Benzodiazepines are effective as hypnotics, however, not without adverse side effects including carryover sedation and performance impairment, anterograde amnesia, and alterations in sleep EEG. Our preliminary ground-based data suggest that pre-sleep administration of 0.3 mg of the pineal hormone melatonin may have the acute hypnotic properties needed for treating the sleep disruption of space flight without producing the adverse side effects associated with benzodiazepines. We hypothesize that pre-sleep administration of melatonin will result in decreased sleep latency, reduced nocturnal sleep disruption, improved sleep efficiency, and enhanced next-day alertness and cognitive performance both in ground-based simulations and during the space shuttle missions. Specifically, we have carried out experiments in which: (1) ambient light intensity aboard the space shuttle is assessed during flight; (2) the impact of space flight on sleep (assessed polysomnographically and actigraphically), respiration during sleep, circadian temperature and melatonin rhythms, waking neurobehavioral alertness and performance is assessed in crew members of the Neurolab and STS-95 missions; (3) the effectiveness of melatonin as a hypnotic is assessed independently of its effects on the phase of the endogenous circadian pacemaker in ground-based studies, using a powerful experimental model of the dyssomnia of space flight; (4) the effectiveness of melatonin as a hypnotic is

  7. Circadian Entrainment, Sleep-Wake Regulation and Neurobehavioral Performance During Extended Duration Space Flight

    Science.gov (United States)

    Czeisler, Charles A.

    1999-01-01

    synchronization of the human circadian pacemaker will be disturbed in men and women by the reduction in LD cycle strength. (2) test the hypothesis that this disturbed circadian synchronization will result in the secretion of the sleep-promoting hormone melatonin during the waking day, disturbed sleep, reduced growth hormone secretion, and impaired performance and daytime alertness; (3) as a countermeasure, test the hypothesis that brief daily exposures to bright light (10,000 lux) will reestablish normal entrained circadian phase, resulting in improved sleep consolidation, normalized sleep structure and endogenous growth hormone secretion and enhanced daytime performance. To date, we have carried out twelve experiments to address Hypotheses I and 2 and data analyses are in progress. The results of the current research may have important implications for the treatment of circadian rhythm sleep disorders, such as delayed sleep phase syndrome and shift-work dyssomnia, which are anticipated to have a high incidence and prevalence during extended duration space flight such as planned for the International Space Station and manned missions to Mars.

  8. 综合医院老年住院患者谵妄影响因素及临床特点分析%Analysis on clinical features and influence factors of elderly in-patients' delirium in general hospitals

    Institute of Scientific and Technical Information of China (English)

    周敏; 刘中华; 佘子瑜; 梁群娣; 周霭婷

    2014-01-01

    目的 探讨综合医院老年住院患者发生谵妄的相关因素及临床特点.方法 回顾性分析2011年1月至2012年12月收治的年龄≥65岁、住院期间发生谵妄的33例患者的临床资料,同期年龄≥65岁的住院患者40例为对照组,将单因素分析差异有统计学意义的指标进行logistic回归分析,研究谵妄发生的影响因素并分析临床特点.结果 研究显示,低氧、机械通气、睡眠障碍、疼痛、电解质紊乱、低血压、重症监护室治疗≥24 h是发生谵妄的主要危险因素(P<0.05),两种以上疾病同时存在时谵妄发生的风险增加.结论 老年患者谵妄发生风险高,综合医院老年住院患者发生谵妄与多重因素相关,同时存在2种或2种以上疾病时风险明显增加,早期识别、控制危险因素、药物治疗是治疗谵妄的有效措施,尽早处理,多数患者可以改善,临床医生对高风险患者及低觉醒型谵妄应给予重视.%Objective To investigate the clinical features and relative factors of elderly inpatients' delirium in general hospitals.Methods A total of 73 elderly in-patients aged over 65 years from our hospital from January 2011 to December 2012 were randomly enrolled in the study.33 cases with the episode of delirium were assigned to the observation group,and 40 cases without delirium were subjected in the control group.The significant influencing factors from single factor analysis for delirium were investigated by logistic regression analysis.Results Multiple logistic repression analysis showed that the major risk factors for delirium were as follows:hypoxia,mechanical ventilation,dyssomnia,pain,electrolyte disorder,and hypotension intensive care time over 24 hours.Moreover,the risk of delirium was increased in the cases with more than one risk factor concurrently.Conclusion The elderly in-patients in general hospital are with higher risk of delirium related to multiple factors.When it comes more than one risk

  9. Fatigue status of elderly patients with COPD and its related factors%老年COPD患者疲乏状况及其相关因素分析

    Institute of Scientific and Technical Information of China (English)

    李慧; 龙纳; 陈茜

    2016-01-01

    目的:了解老年COPD患者疲乏状况及其相关因素,为临床干预提供依据。方法采用疲乏程度量表( FSS)对老年科142例老年COPD患者进行调查。结果老年COPD患者FSS疲乏平均分为(4.4±2.2)分,69.0%存在疲乏,且不同心功能、自理能力、卧床、睡眠障碍、呼吸困难程度者疲乏发生情况不同,有心力衰竭、自理能力障碍、卧床、睡眠障碍、呼吸困难指数高的老年COPD患者疲乏发生率较高,差异有统计学意义(P<0.05);多因素分析结果表明睡眠质量差、呼吸困难指数高及合并心力衰竭是影响老年COPD患者疲乏的主要因素。结论多数老年COPD患者存在疲乏症状,应该加强对患者睡眠障碍呼吸困难指数高及合并心力衰竭患者的临床干预,以减轻患者疲乏症状,从而提高其生活质量。%Objective To learn the fatigue conditions and the related factors of the patients with chronic obstructive pulmonary disease ( COPD ) and provide an evidence for clinical intervention .Methods We used fatigue severity scale ( FSS) to investigate 142 patients who had COPD in our geriatric department .Results The average scores of the FSS in those patients were (4.4 ±2.2).69.0% of them felt fatigued, and their fatigue conditions differ in their heart functions, self-care abilities, sleep qualities, dyspnea degrees when patients, who had heart failure, poor self-care abilities, dyssomnia or high score of dyspnea index, occurred the higher fatigue incidences (P<0.05).The results of multifactor analysis had shown poor sleep ability, high score of dyspnea index and complicated heart failure were the major factors of the fatigue in the patients with COPD.Conclusions Most COPD patients have fatigue .We should strengthen the clinical intervention of sleep quality , high score of dyspnea index and heart failure to decrease the fatigue of the patients , thus to increase their living quality .

  10. Correlation study betWeen Sleep Quality and Microinflammation status in maintenance hemodialysis patients%维持性血液透析患者睡眠质量与微炎性反应状态的相关性研究

    Institute of Scientific and Technical Information of China (English)

    曾艳

    2015-01-01

    目的:研究维持性血液透析患者睡眠质量与微炎性反应状态等因素的相关性,寻求改善睡眠质量的关键点。方法:将入组的147例维持性血液透析患者作为研究对象,根据匹兹堡睡眠质量指数量表( PSQI)将研究对象分为睡眠良好组( PSQI评分≤5分)和睡眠不良组( PSQI评分>5分),收集两组的一般资料及实验室资料为观察项目,通过统计学方法分析观察项目与睡眠质量的相关性。结果:147例维持性血液透析患者睡眠不良的发生率为58.5%。其中年龄、透析龄、BDI评分、SAG评分、hsCRP、血红蛋白、肌酐、血钙、血磷、iPTH比较,差异有统计学意义(P1。结论:微炎性反应状态、透析龄、抑郁、营养不良、血磷、iPTH为睡眠不良的独立危险因素。改善微炎性反应状态、调节iPTH水平及钙磷代谢对睡眠质量至关重要。抑郁对睡眠影响显著,精神层面的治疗与躯体治疗有一样重要的临床意义。%Objective To Study on the correlation between Sleep Quality and Microinflammation status and the other factors in mainte-nance hemodialysis patients for seejing the jey point to improve the quality of sleep. Method The group of 147 maintenance hemodialysis pa-tients as the research object,according to the Pittsburgh Sleep Quality Index( PSQI),they were divided into sleep good group( PSQI score≤5)and poor sleep group(PSQI score > 5),the general information and laboratory data of two groups were collected and analysed by statisti-cal method to investigate the correlation between observed projects and sleepquality. Results The dyssomnia currence rate of 147 maintenance hemodialysis patients was 58. 5%. Signicant differences were shown in age,dialysis duration,BDI score,SAG score,hsCRP,hemoglobin,serum creatinine,serum calcium,serum phosphorus and iPTH,the diffevence was statistically significant( P 1. Conclusion The microinflammatory status

  11. Insônia primária: diagnóstico diferencial e tratamento Primary insomnia: differential diagnosis and treatment

    Directory of Open Access Journals (Sweden)

    Jaime M Monti

    2000-03-01

    Full Text Available A insônia primária é uma dissonia caracterizada pela dificuldade em iniciar e/ou manter o sono e pela sensação de não ter um sono reparador durante um período não inferior a 1 mês. Do ponto de vista polissonográfico, é acompanhada de alterações na indução, na continuidade e na estrutura do sono. Geralmente aparece no adulto jovem, é mais freqüente na mulher e tem um desenvolvimento crônico. A insônia primária é observada de 12,5% a 22,2% dos pacientes portadores de insônia crônica, sendo precedida em freqüência somente na insônia de depressão maior. A insônia primária crônica deve se diferenciar da insônia vinculada a uma higiene inadequada do sono, uma síndrome depressiva ou um transtorno de ansiedade generalizado. O tratamento da insônia primária inclui: higiene adequada do sono, terapia cognitiva e de conduta e uso de fármacos hipnóticos. Entre esses últimos, se destacam o zolpidem e a zopiclona, que melhoram significativamente o sono sem alterar sua estrutura ou induzir a uma reincidência da insônia logo após uma interrupção brusca. Além disso, o desenvolvimento de fármaco-dependência e de vício é muito pouco freqüente.Primary insomnia is a dyssomnia characterized by a complaint of difficulty in initiating or maintaining sleep and the absence of restorative sleep that lasts for at least 1 month. The polysomnographic test shows alterations in the induction, continuity and structure of sleep. Primary insomnia typically begins in young adulthood, has a chronic course, and it is more prevalent among women. Its prevalence among patients with chronic insomnia ranges from 12.5% to 22.2%. Primary insomnia must be distinguished from insomnia related to inadequate sleep hygiene or another mental disorder, such as generalized anxiety disorder or a mood disorder. The treatment of primary insomnia consists of nonpharmacological strategies (sleep hygiene, behavior-cognitive therapy and sleep

  12. Enfermedades del sueño en el recién nacido Sleep disorders in the newborn

    Directory of Open Access Journals (Sweden)

    Israel Alfonso

    2007-01-01

    Full Text Available Las enfermedades del sueño se clasifican en disomnias, parasomnias, enfermedades del sueño asociadas con enfermedades médicas y psiquiátricas, y las propuestas enfermedades del sueño. Solo las parasomnias han sido estudiadas como tales en el recién nacido. Las parasomnias que ocurren en el recién nacido son el síndrome de apnea infantil del sueño, el síndrome de hipoventilación congénita central, el síndrome de muerte infantil súbita, y el mioclono neonatal benigno del sueño. Bajo el término de síndrome de apnea infantil del sueño se agrupan tres entidades: (1 el síndrome de apnea del prematuro, (2 el síndrome de evento que pone en peligro la vida del niño asociado con apnea, y (3 la apnea obstructiva del sueño. El síndrome de hipoventilación central congénito puede estar asociado a otras enfermedades del sistema autónomo tales como la enfermedad de Hirschsprung (síndrome de Haddad y la dismotilidad esofágica, y a tumores del sistema nervioso simpático, especialmente al neuroblastoma. La implementación de la posición supina para dormir y el no fumar en los hogares ha disminuido la frecuencia del síndrome de muerte súbita infantil a 0.85 por 1.000 nacimientos. El mioclono neonatal benigno del sueño debe considerarse en todo recién nacido con un examen normal entre los episodios de mioclonia cuyos episodios sólo ocurren durante el sueño. Esta entidad puede confundirse con status epilepticus, porque los eventos pueden asociarse a aumentos de la frecuencia cardíaca. El uso de las benzodiazepinas puede prolongar la duración de los eventos mioclónicos.Sleep disorders are classified in dyssomnias, parasomnias, sleep disorder associated with medical and psychiatric disorders and proposed sleep disorders. Only the parasomnias have been studied as such in the newborn period. The parasomnias that occur in this age group are infant sleep apnea, congenital central hypoventilation syndrome, sudden infant death syndrome

  13. 汶川地震安置点灾民抑郁症状及影响因素分析%An analysis on depression and influence factors of victims of Wenchuan earthquake in temporary settlements

    Institute of Scientific and Technical Information of China (English)

    陶炯; 王相兰; 温盛霖; 甘照宇; 李雷俊; 郑俩荣; 单鸿; 张晋碚; 李凌江

    2008-01-01

    Objective To investigate the symptoms of depression and influence factors of victims of Wen-chuan Earthquake in temporary settlements in the second week.Method A random sample of 225 cases were as-sessed by using Hamilton Rating Scale for Depression (HRSD),Stanford Acute Stress Reaction Questionnaire (SASRQ),Stress Reaction Questionnaire(SRQ) and a self-designed questionnaire.Result 29.33% of the vic-rims had symptoms of depression,11.11% of the victims had suicidal idea.The total score of HRSD(15.67±11.12) had positive correlation with SASRQ (r=0.725,P<0.01) and SRQ (r=0.767,P<0.01).There were statistical differences of the total score of HRSD(F=4.94,P<0.001),anxiety and somatization,blockade,dys-somnia and feeling of despair among 6 age groups by analysis of variance(ANOVA).The children had lower score of HRSD(10.35±9.17) than the adolescent(16.86±11.82),the middle age(19.31±11.94) and the preseni-urn (P<0.05).The dyssomnia of the female victims(3.27±2.25) was worse than the male(2.59±2.27) (t=2.145,P=0.033).The victims who had lost a loved one had higher scores of HRSD(22.82±13.99) than those with property loss only(14.51±10.06) (t=3.308,P=0.002).According to regression model,SRQ,disturbing degree,and SASRQ significantly explained HRSD variance.(R=0.870,F=95.307,P<0.01).Conclusion The victims had obvious symptoms of depression in the second week after the Wenchuan earthquake.The symptoms of depression had positive correlation with the symptoms of acute stress reaction.The symptoms of depression of children were milder.The female victims and the victims who had lost a loved one in the earthquake should be pay more attention to psychological intervention in the after-disaster.%目的 评估汶川地震后第2周安置点灾民的抑郁症状及影响因素.方法 对江油市太平镇安置点灾民随机抽样后,利用汉密尔顿抑郁量表(HRSD)、斯坦福急性应激反应量表(SASRQ)、应激反应问卷(SRQ)及自编调查问卷进行评估,225

  14. 百乐眠联合坦度螺酮治疗高血压病伴焦虑障碍的疗效及安全性%Effects and safety of Bailemian combined with tandospirone on hypertension patients with anxiety disorder

    Institute of Scientific and Technical Information of China (English)

    钟卓袁; 吕瑞妍; 肖颂华; 杨炼红; 刘军; 刘中霖

    2016-01-01

    with anxiety disorder .Methods Totals of 128 hypertension patients with anxiety disorder were randomly divided into 4 groups as A ,B ,C ,D .Every group received amlodipine 5 mg/d ,group A only received conventional anti -hypertension therapy ,group B received Bailemian 1 .08 g b .i .d ., group C received tandospirone 10 mg t .i .d .,group D received Bailemian 1 .08 g b .i .d .and tandospirone 10mg t .i .d .,all lasted for 12 weeks .Changes from baseline to 4 ,8 and 12 weeks in blood pressure , Hamilton Anxiety Scale (HAMA) and Pittsburgh Sleep Quality Index (PSQI) scores were measured to assess the effects .Treatment Emergent Symptom Scale (TESS) and laboratory tests were used to evalu‐ate the safety .Results The anti-hypertensive effective rates of group C and D were higher than group A at 4 weeks after treatment ,meanwhile which of group B ,C and D were higher than group A at 8 weeks and 12 weeks after treatment .Reduction rate of HAMA and PSQI reflected the improvement of anxiety disorder and dyssomnia separately .Reduction rates of HAMA scores of group B ,C and D were higher than group A at 4 weeks after treatment ,which of group B ,C and D were higher than group A , meanwhile ,which of group C、D were higher than group B .PSQI reduction rates of group B and D were higher than group A at 4 ,8 and 12 weeks after treatment ,which of group C were higher than group A at 8 and 12 weeks after treatment .It was found that the efficiency of treatment at 12 weeks was significant‐ly higher than that at 4 weeks after treatment in group B and D .Response rates for blood pressure ,HA‐MA and PSQI of group D was significantly higher than that of group A ,B and C at 12 weeks after treat‐ment .The differences in all comparison above were statistically significant (P< 0 .05) .The numbers of adverse recation were 15 in A group ,19 in B group ,16 in C group and 26 in D group .Conclusions Bail‐emian can effectively improve the sleep disorders and the curative effect is