WorldWideScience

Sample records for dynamics correction terms

  1. Dynamic term structure models

    DEFF Research Database (Denmark)

    Andreasen, Martin Møller; Meldrum, Andrew

    This paper studies whether dynamic term structure models for US nominal bond yields should enforce the zero lower bound by a quadratic policy rate or a shadow rate specification. We address the question by estimating quadratic term structure models (QTSMs) and shadow rate models with at most four...

  2. Quantum corrections to inflaton and curvaton dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Markkanen, Tommi [Helsinki Institute of Physics and Department of Physics, University of Helsinki, P.O. Box 64, FI-00014, Helsinki (Finland); Tranberg, Anders, E-mail: tommi.markkanen@helsinki.fi, E-mail: anders.tranberg@nbi.dk [Niels Bohr International Academy and Discovery Center, Niels Bohr Institute, Blegdamsvej 17, 2100 Copenhagen (Denmark)

    2012-11-01

    We compute the fully renormalized one-loop effective action for two interacting and self-interacting scalar fields in FRW space-time. We then derive and solve the quantum corrected equations of motion both for fields that dominate the energy density (such as an inflaton) and fields that do not (such as a subdominant curvaton). In particular, we introduce quantum corrected Friedmann equations that determine the evolution of the scale factor. We find that in general, gravitational corrections are negligible for the field dynamics. For the curvaton-type fields this leaves only the effect of the flat-space Coleman-Weinberg-type effective potential, and we find that these can be significant. For the inflaton case, both the corrections to the potential and the Friedmann equations can lead to behaviour very different from the classical evolution. Even to the point that inflation, although present at tree level, can be absent at one-loop order.

  3. Decay correction methods in dynamic PET studies

    International Nuclear Information System (INIS)

    Chen, K.; Reiman, E.; Lawson, M.

    1995-01-01

    In order to reconstruct positron emission tomography (PET) images in quantitative dynamic studies, the data must be corrected for radioactive decay. One of the two commonly used methods ignores physiological processes including blood flow that occur at the same time as radioactive decay; the other makes incorrect use of time-accumulated PET counts. In simulated dynamic PET studies using 11 C-acetate and 18 F-fluorodeoxyglucose (FDG), these methods are shown to result in biased estimates of the time-activity curve (TAC) and model parameters. New methods described in this article provide significantly improved parameter estimates in dynamic PET studies

  4. Assessing atmospheric bias correction for dynamical consistency using potential vorticity

    International Nuclear Information System (INIS)

    Rocheta, Eytan; Sharma, Ashish; Evans, Jason P

    2014-01-01

    Correcting biases in atmospheric variables prior to impact studies or dynamical downscaling can lead to new biases as dynamical consistency between the ‘corrected’ fields is not maintained. Use of these bias corrected fields for subsequent impact studies and dynamical downscaling provides input conditions that do not appropriately represent intervariable relationships in atmospheric fields. Here we investigate the consequences of the lack of dynamical consistency in bias correction using a measure of model consistency—the potential vorticity (PV). This paper presents an assessment of the biases present in PV using two alternative correction techniques—an approach where bias correction is performed individually on each atmospheric variable, thereby ignoring the physical relationships that exists between the multiple variables that are corrected, and a second approach where bias correction is performed directly on the PV field, thereby keeping the system dynamically coherent throughout the correction process. In this paper we show that bias correcting variables independently results in increased errors above the tropopause in the mean and standard deviation of the PV field, which are improved when using the alternative proposed. Furthermore, patterns of spatial variability are improved over nearly all vertical levels when applying the alternative approach. Results point to a need for a dynamically consistent atmospheric bias correction technique which results in fields that can be used as dynamically consistent lateral boundaries in follow-up downscaling applications. (letter)

  5. Global intensity correction in dynamic scenes

    NARCIS (Netherlands)

    Withagen, P.J.; Schutte, K.; Groen, F.C.A.

    2007-01-01

    Changing image intensities causes problems for many computer vision applications operating in unconstrained environments. We propose generally applicable algorithms to correct for global differences in intensity between images recorded with a static or slowly moving camera, regardless of the cause

  6. Does the Boltzmann Principle Need a Dynamical Correction?

    Science.gov (United States)

    Adib, Artur B.

    2004-11-01

    In an attempt to derive thermodynamics from classical mechanics, an approximate expression for the equilibrium temperature of a finite system has been derived (M. Bianucci, R. Mannella, B. J. West and P. Grigolini, Phys. Rev. E 51: 3002 (1995)) which differs from the one that follows from the Boltzmann principle S = kln Ω( E) via the thermodynamic relation 1/ T=∂ S / ∂ E by additional terms of "dynamical" character, which are argued to correct and generalize the Boltzmann principle for small systems (here Ω( E) is the area of the constant-energy surface). In the present work, the underlying definition of temperature in the Fokker-Planck formalism of Bianucci et al., is investigated and shown to coincide with an approximate form of the equipartition temperature. Its exact form, however, is strictly related to the "volume" entropy S = k ln Ф( E) via the thermodynamic relation above for systems of any number of degrees of freedom ( Ф( E) is the phase space volume enclosed by the constant-energy surface). This observation explains and clarifies the numerical results of Bianucci et al., and shows that a dynamical correction for either the temperature or the entropy is unnecessary, at least within the class of systems considered by those authors. Explicit analytical and numerical results for a particle coupled to a small chain ( N~10) of quartic oscillators are also provided to further illustrate these facts.

  7. Relativistic corrections to molecular dynamic dipole polarizabilities

    DEFF Research Database (Denmark)

    Kirpekar, Sheela; Oddershede, Jens; Jensen, Hans Jørgen Aagaard

    1995-01-01

    obtained from the use of the Darwin and mass-velocity operators to first order are included at both levels of approximation. We find that correlation and relativistic contributions are not even approximately additive for the two molecules. The importance of the relativistic corrections is smallest...

  8. Maintenance performance improvement with System Dynamics : A Corrective Maintenance showcase

    NARCIS (Netherlands)

    Deenen, R.E.M.; Van Daalen, C.E.; Koene, E.G.C.

    2008-01-01

    This paper presents a case study of an analysis of a Corrective Maintenance process to realize performance improvement. The Corrective Maintenance process is supported by SAP, which has indicated the performance realisation problem. System Dynamics is used in a Group Model Building process to

  9. Software for Correcting the Dynamic Error of Force Transducers

    Directory of Open Access Journals (Sweden)

    Naoki Miyashita

    2014-07-01

    Full Text Available Software which corrects the dynamic error of force transducers in impact force measurements using their own output signal has been developed. The software corrects the output waveform of the transducers using the output waveform itself, estimates its uncertainty and displays the results. In the experiment, the dynamic error of three transducers of the same model are evaluated using the Levitation Mass Method (LMM, in which the impact forces applied to the transducers are accurately determined as the inertial force of the moving part of the aerostatic linear bearing. The parameters for correcting the dynamic error are determined from the results of one set of impact measurements of one transducer. Then, the validity of the obtained parameters is evaluated using the results of the other sets of measurements of all the three transducers. The uncertainties in the uncorrected force and those in the corrected force are also estimated. If manufacturers determine the correction parameters for each model using the proposed method, and provide the software with the parameters corresponding to each model, then users can obtain the waveform corrected against dynamic error and its uncertainty. The present status and the future prospects of the developed software are discussed in this paper.

  10. Proton radius, Darwin-Foldy term and radiative corrections

    International Nuclear Information System (INIS)

    Jentschura, U.D.

    2011-01-01

    We discuss the role of the so-called Darwin-Foldy term in the evaluation of the proton and deuteron charge radii from atomic hydrogen spectroscopy and nuclear scattering data. The question of whether this term should be included or excluded from the nuclear radius has been controversially discussed in the literature. We attempt to clarify which literature values correspond to which conventions. A detailed discussion of the conventions appears useful because a recent experiment [R. Pohl et al., Nature 466, 213 (2010)] has indicated that there is a discrepancy between the proton charge radii inferred from ordinary ('electronic') atomic hydrogen and muonic hydrogen. We also investigate the role of quantum electrodynamic radiative corrections in the determination of nuclear radii from scattering data, and propose a definition of the nuclear self energy which is compatible with the subtraction of the radiative corrections in scattering experiments. (author)

  11. Surface terms and radiative corrections to the VVA triangle diagram

    International Nuclear Information System (INIS)

    Chowdhury, A.M.; McKeon, G.

    1986-01-01

    The two-loop radiative corrections to the divergence of the axial-vector current are analyzed in the context of spinor electrodynamics. It is found that the arbitrariness that occurs in the relevant Feynman diagrams due to the appearance of surface terms associated with linearly divergent integrals is sufficient to ensure that at two-loop order the Ward identity can be satisfied, irrespective of how the divergences that occur are parametrized. This indicates that the Adler-Bardeen theorem is satisfied

  12. Dynamic Written Corrective Feedback in Developmental Multilingual Writing Classes

    Science.gov (United States)

    Kurzer, Kendon

    2018-01-01

    This study investigated the role of dynamic written corrective feedback (DWCF; Evans, Hartshorn, McCollum, & Wolfersberger, 2010; Hartshorn & Evans, 2015; Hartshorn et al., 2010), a mode of providing specific, targeted, and individualized grammar feedback in developmental English as a second language (ESL) writing classes (pre-first year…

  13. Local field corrections in the lattice dynamics of chromium | Ndukwe ...

    African Journals Online (AJOL)

    This work extends the inclusion of local field corrections in the calculation of the phonon dispersion curves to the transition metal, chromium (Cr3+) using the formalism of lattice dynamics based on the transition metal model potential approach in the adiabatic and hatmonic approximations. The results obtained here have a ...

  14. Beam dynamics in rf guns and emittance correction techniques

    International Nuclear Information System (INIS)

    Serafini, L.

    1994-01-01

    In this paper we present a general review of beam dynamics in a laser-driven rf gun. The peculiarity of such an accelerating structure versus other conventional multi-cell linac structures is underlined on the basis of the Panofsky-Wenzel theorem, which is found to give a theoretical background for the well known Kim's model. A basic explanation for some proposed methods to correct rf induced emittance growth is also derived from the theorem. We also present three emittance correction techniques for the recovery of space-charge induced emittance growth, namely the optimum distributed disk-like bunch technique, the use of rf spatial harmonics to correct spherical aberration induced by space charge forces and the technique of emittance filtering by clipping the electron beam. The expected performances regarding the beam quality achievable with different techniques, as predicted by scaling laws and simulations, are analyzed, and, where available, compared to experimental results. (orig.)

  15. On the quantum dynamical foundations of collision terms

    International Nuclear Information System (INIS)

    Nemes, M.C.; Toledo Piza, A.F.R. de

    1981-08-01

    Collision terms are non-unitary corrections usually added to mean field descriptions in order to describe dissipative effects. Derivations of collision terms usually include assumptions which lack an explicit connection with a fully quantum dynamical description. Quantum dynamical foundations of collision terms are examined: they are shown to reflect the dynamics of quantum correlations. A careful study of the non-unitary aspects of the evolution of quantum correlations leads naturally to an unambiguous definition of a collision term. This collision term is shown to obey a non-linear pre-master equation, whose derivation is fully quantum-mechanical. Moreover, it is shown that quantum correlations also yield an unitary correction to the mean field description, which could be absorbed in a suitable redefinition of the mean field. Formal expressions for these corrections are derived and their connection with memory effects exhibited explicitely. The typical time of evaluation of quantum correlations allows for an analytical expression for the 'lifetime of mean field descriptions'. Finally, a quantum mechanical point of view for 'irreversibility' in deep inelastic is discussed. (Author) [pt

  16. Analysis of dynamical corrections to baryon magnetic moments

    International Nuclear Information System (INIS)

    Ha, Phuoc; Durand, Loyal

    2003-01-01

    We present and analyze QCD corrections to the baryon magnetic moments in terms of the one-, two-, and three-body operators which appear in the effective field theory developed in our recent papers. The main corrections are extended Thomas-type corrections associated with the confining interactions in the baryon. We investigate the contributions of low-lying angular excitations to the baryon magnetic moments quantitatively and show that they are completely negligible. When the QCD corrections are combined with the nonquark model contributions of the meson loops, we obtain a model which describes the baryon magnetic moments within a mean deviation of 0.04 μ N . The nontrivial interplay of the two types of corrections to the quark-model magnetic moments is analyzed in detail, and explains why the quark model is so successful. In the course of these calculations, we parametrize the general spin structure of the j=(1/2) + baryon wave functions in a form which clearly displays the symmetry properties and the internal angular momentum content of the wave functions, and allows us to use spin-trace methods to calculate the many spin matrix elements which appear in the expressions for the baryon magnetic moments. This representation may be useful elsewhere

  17. Correction

    DEFF Research Database (Denmark)

    Pinkevych, Mykola; Cromer, Deborah; Tolstrup, Martin

    2016-01-01

    [This corrects the article DOI: 10.1371/journal.ppat.1005000.][This corrects the article DOI: 10.1371/journal.ppat.1005740.][This corrects the article DOI: 10.1371/journal.ppat.1005679.].......[This corrects the article DOI: 10.1371/journal.ppat.1005000.][This corrects the article DOI: 10.1371/journal.ppat.1005740.][This corrects the article DOI: 10.1371/journal.ppat.1005679.]....

  18. Emergence of spacetime dynamics in entropy corrected and braneworld models

    International Nuclear Information System (INIS)

    Sheykhi, A.; Dehghani, M.H.; Hosseini, S.E.

    2013-01-01

    A very interesting new proposal on the origin of the cosmic expansion was recently suggested by Padmanabhan [arXiv:1206.4916]. He argued that the difference between the surface degrees of freedom and the bulk degrees of freedom in a region of space drives the accelerated expansion of the universe, as well as the standard Friedmann equation through relation ΔV = Δt(N sur −N bulk ). In this paper, we first present the general expression for the number of degrees of freedom on the holographic surface, N sur , using the general entropy corrected formula S = A/(4L p 2 )+s(A). Then, as two example, by applying the Padmanabhan's idea we extract the corresponding Friedmann equations in the presence of power-law and logarithmic correction terms in the entropy. We also extend the study to RS II and DGP braneworld models and derive successfully the correct form of the Friedmann equations in these theories. Our study further supports the viability of Padmanabhan's proposal

  19. Nonlinear Correction Schemes for the Phase 1 LHC Insertion Region Upgrade and Dynamic Aperture Studies

    CERN Document Server

    de Maria, R; Tomás, R

    2009-01-01

    The Phase 1 LHC Interaction Region (IR) upgrade aims at increasing the machine luminosity essentially by reducing the beam size at the Interaction Point (IP). This requires a total redesign of the full IR. A large set of options has been proposed with conceptually different designs. This paper reports on a general approach for the compensation of the multipolar errors of the IR magnets in the design phase. The goal is to use the same correction approach for the different designs. The correction algorithm is based on the minimization of the differences between the IR transfer map with errors and the design IR transfer map. Its performance is tested using the dynamic aperture as figure of merit. The relation between map coefficients and resonance terms is also given as a way to target particular resonances by selecting the right map coefficients. The dynamic aperture is studied versus magnet aperture using recently established relations between magnetic errors and magnet aperture.

  20. A Monte Carlo procedure for Hamiltonians with small nonlocal correction terms

    International Nuclear Information System (INIS)

    Mack, G.; Pinn, K.

    1986-03-01

    We consider lattice field theories whose Hamiltonians contain small nonlocal correction terms. We propose to do simulations for an auxiliarly polymer system with field dependent activities. If a nonlocal correction term to the Hamiltonian is small, it need to be evaluated only rarely. (orig.)

  1. A new dynamical downscaling approach with GCM bias corrections and spectral nudging

    Science.gov (United States)

    Xu, Zhongfeng; Yang, Zong-Liang

    2015-04-01

    To improve confidence in regional projections of future climate, a new dynamical downscaling (NDD) approach with both general circulation model (GCM) bias corrections and spectral nudging is developed and assessed over North America. GCM biases are corrected by adjusting GCM climatological means and variances based on reanalysis data before the GCM output is used to drive a regional climate model (RCM). Spectral nudging is also applied to constrain RCM-based biases. Three sets of RCM experiments are integrated over a 31 year period. In the first set of experiments, the model configurations are identical except that the initial and lateral boundary conditions are derived from either the original GCM output, the bias-corrected GCM output, or the reanalysis data. The second set of experiments is the same as the first set except spectral nudging is applied. The third set of experiments includes two sensitivity runs with both GCM bias corrections and nudging where the nudging strength is progressively reduced. All RCM simulations are assessed against North American Regional Reanalysis. The results show that NDD significantly improves the downscaled mean climate and climate variability relative to other GCM-driven RCM downscaling approach in terms of climatological mean air temperature, geopotential height, wind vectors, and surface air temperature variability. In the NDD approach, spectral nudging introduces the effects of GCM bias corrections throughout the RCM domain rather than just limiting them to the initial and lateral boundary conditions, thereby minimizing climate drifts resulting from both the GCM and RCM biases.

  2. Dynamic origins of fermionic D -terms

    Science.gov (United States)

    Hudson, Jonathan; Schweitzer, Peter

    2018-03-01

    The D -term is defined through matrix elements of the energy-momentum tensor, similarly to mass and spin, yet this important particle property is experimentally not known any fermion. In this work we show that the D -term of a spin 1/2 fermion is of dynamical origin: it vanishes for a free fermion. This is in pronounced contrast to the bosonic case where already a free spin-0 boson has a non-zero intrinsic D -term. We illustrate in two simple models how interactions generate the D -term of a fermion with an internal structure, the nucleon. All known matter is composed of elementary fermions. This indicates the importance to study this interesting particle property in more detail, which will provide novel insights especially on the structure of the nucleon.

  3. The Dynamics of Terms in Accounting

    DEFF Research Database (Denmark)

    Fuertes-Olivera, Pedro A.; Nielsen, Sandro

    2011-01-01

    . However, an analysis of online dictionaries shows that these cannot cope with the dynamic nature of accounting terminology. We discuss a network of internet dictionaries in English, Danish, and Spanish that was compiled using the functional approach to specialised lexicography. We show how terminologists...... can work in subject fields where culture and context play a key role in the development of nationally accepted and internationally recommended terms, and propose ways to remedy deficiencies identified in the dictionaries examined. Finally, we discuss strategies for translating English metaphorical......European accounting terminology is dynamic as term creation and formation occurs on national, European Union and international levels. Although English is the lingua franca of accounting, international accounting standards in English exist on a par with their translations into other languages...

  4. Implementation of dynamic cross-talk correction (DCTC) for MOX holdup assay measurements among multiple gloveboxes

    International Nuclear Information System (INIS)

    Nakamichi, Hideo; Nakamura, Hironobu; Mukai, Yasunobu; Kurita, Tsutomu; Beddingfield, David H.

    2012-01-01

    Plutonium holdup in gloveboxes (GBs) are measured by (passive neutron based NDA (HBAS) for the material control and accountancy (MC and A) at Plutonium Conversion Development Facility (PCDF). In the case that the GBs are installed close to one another, the cross-talk which means neutron double counting among GBs should be corrected properly. Though we used to use predetermined constants as the cross-talk correction, a new correction methodology for neutron cross-talk among the GBs with inventory changes is required for the improvement of MC and A. In order to address the issue of variable cross-talk contributions to holdup assay values, we applied a dynamic cross-talk correction (DCTC) method, based on the distributed source-term analysis approach, to obtain the actual doubles derived from the cross-talk between multiple GBs. As a result of introduction of DCTC for HBAS measurement, we could reduce source biases from the assay result by estimating the reliable doubles-counting derived from the cross-talk. Therefore, we could improve HBAS measurement uncertainty to a half of conventional system, and we are going to confirm the result. Since the DCTC methodology can be used to determine the cross-correlation among multiple inventories in small areas, it is expected that this methodology can be extended to the knowledge of safeguards by design. (author)

  5. Local Dynamic Reactive Power for Correction of System Voltage Problems

    Energy Technology Data Exchange (ETDEWEB)

    Kueck, John D [ORNL; Rizy, D Tom [ORNL; Li, Fangxing [ORNL; Xu, Yan [ORNL; Li, Huijuan [University of Tennessee, Knoxville (UTK); Adhikari, Sarina [ORNL; Irminger, Philip [ORNL

    2008-12-01

    Distribution systems are experiencing outages due to a phenomenon known as local voltage collapse. Local voltage collapse is occurring in part because modern air conditioner compressor motors are much more susceptible to stalling during a voltage dip than older motors. These motors can stall in less than 3 cycles (.05s) when a fault, such as on the sub-transmission system, causes voltage to sag to 70 to 60%. The reasons for this susceptibility are discussed in the report. During the local voltage collapse, voltages are depressed for a period of perhaps one or two minutes. There is a concern that these local events are interacting together over larger areas and may present a challenge to system reliability. An effective method of preventing local voltage collapse is the use of voltage regulation from Distributed Energy Resources (DER) that can supply or absorb reactive power. DER, when properly controlled, can provide a rapid correction to voltage dips and prevent motor stall. This report discusses the phenomenon and causes of local voltage collapse as well as the control methodology we have developed to counter voltage sag. The problem is growing because of the use of low inertia, high efficiency air conditioner (A/C) compressor motors and because the use of electric A/C is growing in use and becoming a larger percentage of system load. A method for local dynamic voltage regulation is discussed which uses reactive power injection or absorption from local DER. This method is independent, rapid, and will not interfere with conventional utility system voltage control. The results of simulations of this method are provided. The method has also been tested at the ORNL s Distributed Energy Communications and Control (DECC) Laboratory using our research inverter and synchronous condenser. These systems at the DECC Lab are interconnected to an actual distribution system, the ORNL distribution system, which is fed from TVA s 161kV sub-transmission backbone. The test results

  6. Dynamic retardation corrections to the mass spectrum of heavy quarkonia

    International Nuclear Information System (INIS)

    Kopalejshvili, T.; Rusetskij, A.

    1996-01-01

    In the framework of the Logunov-Tavkhelidze quasipotential approach the first-order retardation corrections to the heavy quarkonia mass spectrum are calculated with the use of the stationary wave boundary condition in the covariant kernel of the Bethe-Salpeter equation. As has been expected, these corrections turn out to be small for all low-lying heavy meson states and vanish in the heavy quark limit (m Q →∞). The comparison of the suggested approach to the calculation of retardation corrections with others, known in literature, is carried out. 22 refs., 1 tab

  7. Dynamic PET image reconstruction integrating temporal regularization associated with respiratory motion correction for applications in oncology

    Science.gov (United States)

    Merlin, Thibaut; Visvikis, Dimitris; Fernandez, Philippe; Lamare, Frédéric

    2018-02-01

    Respiratory motion reduces both the qualitative and quantitative accuracy of PET images in oncology. This impact is more significant for quantitative applications based on kinetic modeling, where dynamic acquisitions are associated with limited statistics due to the necessity of enhanced temporal resolution. The aim of this study is to address these drawbacks, by combining a respiratory motion correction approach with temporal regularization in a unique reconstruction algorithm for dynamic PET imaging. Elastic transformation parameters for the motion correction are estimated from the non-attenuation-corrected PET images. The derived displacement matrices are subsequently used in a list-mode based OSEM reconstruction algorithm integrating a temporal regularization between the 3D dynamic PET frames, based on temporal basis functions. These functions are simultaneously estimated at each iteration, along with their relative coefficients for each image voxel. Quantitative evaluation has been performed using dynamic FDG PET/CT acquisitions of lung cancer patients acquired on a GE DRX system. The performance of the proposed method is compared with that of a standard multi-frame OSEM reconstruction algorithm. The proposed method achieved substantial improvements in terms of noise reduction while accounting for loss of contrast due to respiratory motion. Results on simulated data showed that the proposed 4D algorithms led to bias reduction values up to 40% in both tumor and blood regions for similar standard deviation levels, in comparison with a standard 3D reconstruction. Patlak parameter estimations on reconstructed images with the proposed reconstruction methods resulted in 30% and 40% bias reduction in the tumor and lung region respectively for the Patlak slope, and a 30% bias reduction for the intercept in the tumor region (a similar Patlak intercept was achieved in the lung area). Incorporation of the respiratory motion correction using an elastic model along with a

  8. Importance of the CMAP Correction to the CHARMM22 Protein Force Field: Dynamics of Hen Lysozyme

    OpenAIRE

    Buck, Matthias; Bouguet-Bonnet, Sabine; Pastor, Richard W.; MacKerell, Alexander D.

    2005-01-01

    The recently developed CMAP correction to the CHARMM22 force field (C22) is evaluated from 25 ns molecular dynamics simulations on hen lysozyme. Substantial deviations from experimental backbone root mean-square fluctuations and N-H NMR order parameters obtained in the C22 trajectories (especially in the loops) are eliminated by the CMAP correction. Thus, the C22/CMAP force field yields improved dynamical and structural properties of proteins in molecular dynamics simulations.

  9. From M-theory higher curvature terms to α′ corrections in F-theory

    Directory of Open Access Journals (Sweden)

    Thomas W. Grimm

    2016-02-01

    Full Text Available We perform a Kaluza–Klein reduction of eleven-dimensional supergravity on a Calabi–Yau fourfold including terms quartic and cubic in the Riemann curvature and determine the induced corrections to the three-dimensional two-derivative N=2 effective action. We focus on the effective Einstein–Hilbert term and the kinetic terms for vectors. Dualizing the vectors into scalars, we derive the resulting Kähler potential and complex coordinates. The classical expressions for the Kähler coordinates are non-trivially modified by terms containing the third Chern form of the background Calabi–Yau fourfold, while the functional form of the Kähler potential is shown to be uncorrected. We omit terms proportional to the non-harmonic part of the third Chern form. For elliptically fibered Calabi–Yau fourfolds the corrections can be uplifted to a four-dimensional F-theory compactification. We argue that also the four-dimensional N=1 Kähler coordinates receive non-trivial corrections. We find a simple expression for the induced corrections for different Abelian and non-Abelian seven-brane configurations by scanning over many Calabi–Yau fourfolds with resolved singularities. The interpretation of this expression leads us to conjecture that the higher-curvature corrections correspond to α′2 corrections that arise from open strings at the self-intersection of seven-branes.

  10. Standard Model-like corrections to Dilatonic Dynamics

    DEFF Research Database (Denmark)

    Antipin, Oleg; Krog, Jens; Mølgaard, Esben

    2013-01-01

    the same non-abelian global symmetries as a technicolor-like theory with matter in a complex representation of the gauge group. We then embed the electroweak gauge group within the global flavor structure and add also ordinary quark-like states to mimic the effects of the top. We find that the standard...... model-like induced corrections modify the original phase diagram and the details of the dilatonic spectrum. In particular, we show that the corrected theory exhibits near-conformal behavior for a smaller range of flavors and colors. For this range of values, however, our results suggest that near...

  11. Dissipative dynamics with the corrected propagator method. Numerical comparison between fully quantum and mixed quantum/classical simulations

    International Nuclear Information System (INIS)

    Gelman, David; Schwartz, Steven D.

    2010-01-01

    The recently developed quantum-classical method has been applied to the study of dissipative dynamics in multidimensional systems. The method is designed to treat many-body systems consisting of a low dimensional quantum part coupled to a classical bath. Assuming the approximate zeroth order evolution rule, the corrections to the quantum propagator are defined in terms of the total Hamiltonian and the zeroth order propagator. Then the corrections are taken to the classical limit by introducing the frozen Gaussian approximation for the bath degrees of freedom. The evolution of the primary part is governed by the corrected propagator yielding the exact quantum dynamics. The method has been tested on two model systems coupled to a harmonic bath: (i) an anharmonic (Morse) oscillator and (ii) a double-well potential. The simulations have been performed at zero temperature. The results have been compared to the exact quantum simulations using the surrogate Hamiltonian approach.

  12. Correction

    CERN Multimedia

    2002-01-01

    Tile Calorimeter modules stored at CERN. The larger modules belong to the Barrel, whereas the smaller ones are for the two Extended Barrels. (The article was about the completion of the 64 modules for one of the latter.) The photo on the first page of the Bulletin n°26/2002, from 24 July 2002, illustrating the article «The ATLAS Tile Calorimeter gets into shape» was published with a wrong caption. We would like to apologise for this mistake and so publish it again with the correct caption.

  13. Optimal superadiabatic population transfer and gates by dynamical phase corrections

    Science.gov (United States)

    Vepsäläinen, A.; Danilin, S.; Paraoanu, G. S.

    2018-04-01

    In many quantum technologies adiabatic processes are used for coherent quantum state operations, offering inherent robustness to errors in the control parameters. The main limitation is the long operation time resulting from the requirement of adiabaticity. The superadiabatic method allows for faster operation, by applying counterdiabatic driving that corrects for excitations resulting from the violation of the adiabatic condition. In this article we show how to construct the counterdiabatic Hamiltonian in a system with forbidden transitions by using two-photon processes and how to correct for the resulting time-dependent ac-Stark shifts in order to enable population transfer with unit fidelity. We further demonstrate that superadiabatic stimulated Raman passage can realize a robust unitary NOT-gate between the ground state and the second excited state of a three-level system. The results can be readily applied to a three-level transmon with the ladder energy level structure.

  14. Dynamic stresses, coulomb failure, and remote triggering: corrected

    Science.gov (United States)

    Hill, David P.

    2012-01-01

    Dynamic stresses associated with crustal surface waves with 15–30 s periods and peak amplitudes Coulomb failure models based on a frictional strength threshold offer one explanation for instances of rapid‐onset triggered seismicity that develop during the surface‐wave peak dynamic stressing. Evaluation of the triggering potential of surface‐wave dynamic stresses acting on critically stressed faults using a Mohr’s circle representation together with the Coulomb failure criteria indicates that Love waves should have a higher triggering potential than Rayleigh waves for most fault orientations and wave incidence angles. That (1) the onset of triggered seismicity often appears to begin during the Rayleigh wave rather than the earlier arriving Love wave, and (2) Love‐wave amplitudes typically exceed those for Rayleigh waves suggests that the explanation for rapid‐onset dynamic triggering may not reside solely with a simple static‐threshold friction mode. The results also indicate that normal faults should be more susceptible to dynamic triggering by 20‐s Rayleigh‐wave stresses than thrust faults in the shallow seismogenic crust (<10  km) while the advantage tips in favor of reverse faults greater depths. This transition depth scales with wavelength and coincides roughly with the transition from retrograde‐to‐prograde particle motion. Locally elevated pore pressures may have a role in the observed prevalence of dynamic triggering in extensional regimes and geothermal/volcanic systems. The result is consistent with the apparent elevated susceptibility of extensional or transtensional tectonic regimes to remote triggering by Rayleigh‐wave dynamic stresses than compressional or transpressional regimes.

  15. Correction

    Directory of Open Access Journals (Sweden)

    2012-01-01

    Full Text Available Regarding Gorelik, G., & Shackelford, T.K. (2011. Human sexual conflict from molecules to culture. Evolutionary Psychology, 9, 564–587: The authors wish to correct an omission in citation to the existing literature. In the final paragraph on p. 570, we neglected to cite Burch and Gallup (2006 [Burch, R. L., & Gallup, G. G., Jr. (2006. The psychobiology of human semen. In S. M. Platek & T. K. Shackelford (Eds., Female infidelity and paternal uncertainty (pp. 141–172. New York: Cambridge University Press.]. Burch and Gallup (2006 reviewed the relevant literature on FSH and LH discussed in this paragraph, and should have been cited accordingly. In addition, Burch and Gallup (2006 should have been cited as the originators of the hypothesis regarding the role of FSH and LH in the semen of rapists. The authors apologize for this oversight.

  16. Correction

    CERN Multimedia

    2002-01-01

    The photo on the second page of the Bulletin n°48/2002, from 25 November 2002, illustrating the article «Spanish Visit to CERN» was published with a wrong caption. We would like to apologise for this mistake and so publish it again with the correct caption.   The Spanish delegation, accompanied by Spanish scientists at CERN, also visited the LHC superconducting magnet test hall (photo). From left to right: Felix Rodriguez Mateos of CERN LHC Division, Josep Piqué i Camps, Spanish Minister of Science and Technology, César Dopazo, Director-General of CIEMAT (Spanish Research Centre for Energy, Environment and Technology), Juan Antonio Rubio, ETT Division Leader at CERN, Manuel Aguilar-Benitez, Spanish Delegate to Council, Manuel Delfino, IT Division Leader at CERN, and Gonzalo León, Secretary-General of Scientific Policy to the Minister.

  17. Correction

    Directory of Open Access Journals (Sweden)

    2014-01-01

    Full Text Available Regarding Tagler, M. J., and Jeffers, H. M. (2013. Sex differences in attitudes toward partner infidelity. Evolutionary Psychology, 11, 821–832: The authors wish to correct values in the originally published manuscript. Specifically, incorrect 95% confidence intervals around the Cohen's d values were reported on page 826 of the manuscript where we reported the within-sex simple effects for the significant Participant Sex × Infidelity Type interaction (first paragraph, and for attitudes toward partner infidelity (second paragraph. Corrected values are presented in bold below. The authors would like to thank Dr. Bernard Beins at Ithaca College for bringing these errors to our attention. Men rated sexual infidelity significantly more distressing (M = 4.69, SD = 0.74 than they rated emotional infidelity (M = 4.32, SD = 0.92, F(1, 322 = 23.96, p < .001, d = 0.44, 95% CI [0.23, 0.65], but there was little difference between women's ratings of sexual (M = 4.80, SD = 0.48 and emotional infidelity (M = 4.76, SD = 0.57, F(1, 322 = 0.48, p = .29, d = 0.08, 95% CI [−0.10, 0.26]. As expected, men rated sexual infidelity (M = 1.44, SD = 0.70 more negatively than they rated emotional infidelity (M = 2.66, SD = 1.37, F(1, 322 = 120.00, p < .001, d = 1.12, 95% CI [0.85, 1.39]. Although women also rated sexual infidelity (M = 1.40, SD = 0.62 more negatively than they rated emotional infidelity (M = 2.09, SD = 1.10, this difference was not as large and thus in the evolutionary theory supportive direction, F(1, 322 = 72.03, p < .001, d = 0.77, 95% CI [0.60, 0.94].

  18. Limitations and corrections in measuring dynamic characteristics of structural systems

    International Nuclear Information System (INIS)

    Walter, P.L.

    1978-10-01

    The work deals with limitations encountered in measuring the dynamic characteristics of structural systems. Structural loading and response are measured by transducers possessing multiple resonant frequencies in their transfer function. In transient environments, the resultant signals from these transducers are shown to be analytically unpredictable in amplitude level and frequency content. Data recorded during nuclear effects simulation testing on structures are analyzed. Results of analysis can be generalized to any structure which encounters dynamic loading. Methods to improve the recorded data are described which can be implemented on a frequency selective basis during the measurement process. These improvements minimize data distortion attributable to the transfer characteristics of the measuring transducers

  19. Motion detection and correction for dynamic 15O-water myocardial perfusion PET studies

    International Nuclear Information System (INIS)

    Naum, Alexandru; Laaksonen, Marko S.; Oikonen, Vesa; Teraes, Mika; Jaervisalo, Mikko J.; Knuuti, Juhani; Tuunanen, Helena; Nuutila, Pirjo; Kemppainen, Jukka

    2005-01-01

    Patient motion during dynamic PET studies is a well-documented source of errors. The purpose of this study was to investigate the incidence of frame-to-frame motion in dynamic 15 O-water myocardial perfusion PET studies, to test the efficacy of motion correction methods and to study whether implementation of motion correction would have an impact on the perfusion results. We developed a motion detection procedure using external radioactive skin markers and frame-to-frame alignment. To evaluate motion, marker coordinates inside the field of view were determined in each frame for each study. The highest number of frames with identical spatial coordinates during the study were defined as ''non-moved''. Movement was considered present if even one marker changed position, by one pixel/frame compared with reference, in one axis, and such frames were defined as ''moved''. We tested manual, in-house-developed motion correction software and an automatic motion correction using a rigid body point model implemented in MIPAV (Medical Image Processing, Analysis and Visualisation) software. After motion correction, remaining motion was re-analysed. Myocardial blood flow (MBF) values were calculated for both non-corrected and motion-corrected datasets. At rest, patient motion was found in 18% of the frames, but during pharmacological stress the fraction increased to 45% and during physical exercise it rose to 80%. Both motion correction algorithms significantly decreased (p<0.006) the number of moved frames and the amplitude of motion (p<0.04). Motion correction significantly increased MBF results during bicycle exercise (p<0.02). At rest or during adenosine infusion, the motion correction had no significant effects on MBF values. Significant motion is a common phenomenon in dynamic cardiac studies during adenosine infusion but especially during exercise. Applying motion correction for the data acquired during exercise clearly changed the MBF results, indicating that motion

  20. Technicolor dynamics corrections to Wt-barb coupling

    International Nuclear Information System (INIS)

    Yue Chongxing; Huang Jinshu; Lu Gongru; Yang Zhengtao

    1998-01-01

    The authors consider the contributions of new gauge bosons to Wt-barb coupling in one generation technicolor (OGTC) model and topcolor assisted multiscale technicolor (TOPCMTC) model. The authors find that the exchange of diagonal extended technicolor (ETC) gauge boson has no contribution to Wt-barb coupling. Using the LEP value of R b , the authors calculate the corrections to the CKM matrix element V tb which arise from the sideways ETC gauge boson in OGTC model and the sideways ETC gauge bosons and color exchange in TOPCMTC model. The authors find that the δV tb is significantly large for a certain set of the parameters of either OGTC model or TOPCMTC model which might be detected in the Fermilab Tevatron Run 3 experiments

  1. Backtracking dynamics of RNA polymerase: pausing and error correction

    Science.gov (United States)

    Sahoo, Mamata; Klumpp, Stefan

    2013-09-01

    Transcription by RNA polymerases is frequently interrupted by pauses. One mechanism of such pauses is backtracking, where the RNA polymerase translocates backward with respect to both the DNA template and the RNA transcript, without shortening the transcript. Backtracked RNA polymerases move in a diffusive fashion and can return to active transcription either by diffusive return to the position where backtracking was initiated or by cleaving the transcript. The latter process also provides a mechanism for proofreading. Here we present some exact results for a kinetic model of backtracking and analyse its impact on the speed and the accuracy of transcription. We show that proofreading through backtracking is different from the classical (Hopfield-Ninio) scheme of kinetic proofreading. Our analysis also suggests that, in addition to contributing to the accuracy of transcription, backtracking may have a second effect: it attenuates the slow down of transcription that arises as a side effect of discriminating between correct and incorrect nucleotides based on the stepping rates.

  2. Angstrom analysis with dynamic in-situ aberration corrected electron microscopy

    International Nuclear Information System (INIS)

    Gai, P L; Boyes, E D

    2010-01-01

    Following the pioneering development of atomic resolution in-situ environmental TEM (ETEM) for direct probing of gas-solid reactions, recent developments are presented of dynamic real time in-situ studies at the Angstrom level in an aberration corrected electron microscope. The in-situ data from Pt-Pd nanoparticles on carbon with the corresponding FFT/optical diffractogram (OD) illustrate an achieved resolution of 0 C and higher, in a double aberration corrected JEOL 2200 FS TEM/STEM employing a wider gap objective pole piece and gas tolerant TMP column pumping system. Direct observations of dynamic biofuel catalysts under controlled calcinations conditions and quantified with catalytic reactivity and physico-chemical studies show the benefits in-situ aberration correction in unveiling the evolution of surface active sites necessary for the development efficient heterogeneous catalysts. The new results open up opportunities for dynamic studies of materials in an aberration corrected environment and direct future development activities.

  3. Understanding the dynamics of correct and error responses in free recall: evidence from externalized free recall.

    Science.gov (United States)

    Unsworth, Nash; Brewer, Gene A; Spillers, Gregory J

    2010-06-01

    The dynamics of correct and error responses in a variant of delayed free recall were examined in the present study. In the externalized free recall paradigm, participants were presented with lists of words and were instructed to subsequently recall not only the words that they could remember from the most recently presented list, but also any other words that came to mind during the recall period. Externalized free recall is useful for elucidating both sampling and postretrieval editing processes, thereby yielding more accurate estimates of the total number of error responses, which are typically sampled and subsequently edited during free recall. The results indicated that the participants generally sampled correct items early in the recall period and then transitioned to sampling more erroneous responses. Furthermore, the participants generally terminated their search after sampling too many errors. An examination of editing processes suggested that the participants were quite good at identifying errors, but this varied systematically on the basis of a number of factors. The results from the present study are framed in terms of generate-edit models of free recall.

  4. Physiologic noise regression, motion regression, and TOAST dynamic field correction in complex-valued fMRI time series.

    Science.gov (United States)

    Hahn, Andrew D; Rowe, Daniel B

    2012-02-01

    As more evidence is presented suggesting that the phase, as well as the magnitude, of functional MRI (fMRI) time series may contain important information and that there are theoretical drawbacks to modeling functional response in the magnitude alone, removing noise in the phase is becoming more important. Previous studies have shown that retrospective correction of noise from physiologic sources can remove significant phase variance and that dynamic main magnetic field correction and regression of estimated motion parameters also remove significant phase fluctuations. In this work, we investigate the performance of physiologic noise regression in a framework along with correction for dynamic main field fluctuations and motion regression. Our findings suggest that including physiologic regressors provides some benefit in terms of reduction in phase noise power, but it is small compared to the benefit of dynamic field corrections and use of estimated motion parameters as nuisance regressors. Additionally, we show that the use of all three techniques reduces phase variance substantially, removes undesirable spatial phase correlations and improves detection of the functional response in magnitude and phase. Copyright © 2011 Elsevier Inc. All rights reserved.

  5. Fermionic corrections to fluid dynamics from BTZ black hole

    Energy Technology Data Exchange (ETDEWEB)

    Gentile, L.G.C. [DISIT, Università del Piemonte Orientale,via T. Michel, 11, Alessandria, 15120 (Italy); Dipartimento di Fisica “Galileo Galilei”,Università di Padova, via Marzolo 8, 35131 Padova (Italy); INFN - Sezione di Padova,via Marzolo 8, 35131, Padova (Italy); Grassi, P.A. [DISIT, Università del Piemonte Orientale,via T. Michel, 11, Alessandria, 15120 (Italy); INFN - Gruppo Collegato di Alessandria, Sezione di Torino,Alessandria (Italy); PH-TH Department, CERN,CH-1211 Geneva 23 (Switzerland); Mezzalira, A. [Dipartimento di Fisica Teorica, Università di Torino,via P. Giuria, 1, Torino, 10125 (Italy); INFN - Gruppo Collegato di Alessandria, Sezione di Torino,Alessandria (Italy)

    2015-11-23

    We reconstruct the complete fermionic orbit of the non-extremal BTZ black hole by acting with finite supersymmetry transformations. The solution satisfies the exact supergravity equations of motion to all orders in the fermonic expansion and the final result is given in terms of fermionic bilinears. By fluid/gravity correspondence, we derive linearized Navier-Stokes equations and a set of new differential equations from Rarita-Schwinger equation. We compute the boundary energy-momentum tensor and we interpret the result as a perfect fluid with a modified definition of fluid velocity. Finally, we derive the modified expression for the entropy of the black hole in terms of the fermionic bilinears.

  6. Backtracking dynamics of RNA polymerase: pausing and error correction

    International Nuclear Information System (INIS)

    Sahoo, Mamata; Klumpp, Stefan

    2013-01-01

    Transcription by RNA polymerases is frequently interrupted by pauses. One mechanism of such pauses is backtracking, where the RNA polymerase translocates backward with respect to both the DNA template and the RNA transcript, without shortening the transcript. Backtracked RNA polymerases move in a diffusive fashion and can return to active transcription either by diffusive return to the position where backtracking was initiated or by cleaving the transcript. The latter process also provides a mechanism for proofreading. Here we present some exact results for a kinetic model of backtracking and analyse its impact on the speed and the accuracy of transcription. We show that proofreading through backtracking is different from the classical (Hopfield–Ninio) scheme of kinetic proofreading. Our analysis also suggests that, in addition to contributing to the accuracy of transcription, backtracking may have a second effect: it attenuates the slow down of transcription that arises as a side effect of discriminating between correct and incorrect nucleotides based on the stepping rates. (paper)

  7. Short-term Consumer Benefits of Dynamic Pricing

    OpenAIRE

    Dupont, Benjamin; De Jonghe, Cedric; Kessels, Kris; Belmans, Ronnie

    2011-01-01

    Consumer benefits of dynamic pricing depend on a variety of factors. Consumer characteristics and climatic circumstances widely differ, which forces a regional comparison. This paper presents a general overview of demand response programs and focuses on the short-term benefits of dynamic pricing for an average Flemish residential consumer. It reaches a methodology to develop a cost reflective dynamic pricing program and to estimate short-term bill savings. Participating in a dynamic pricing p...

  8. Dynamic Correction of Higher-Order Deflection Aberrations in the Environmental SEM

    Czech Academy of Sciences Publication Activity Database

    Oral, Martin; Neděla, Vilém

    2015-01-01

    Roč. 21, S4 (2015), s. 194-199 ISSN 1431-9276 R&D Projects: GA ČR(CZ) GA14-22777S; GA MŠk(CZ) LO1212 Institutional support: RVO:68081731 Keywords : environmental SEM * ESEM * shifted deflection pivot point * Higher order deflection aberrations * vignetting * dynamic focusing * dynamic stigmator * dynamic correction Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.730, year: 2015

  9. Fetal cardiac cine imaging using highly accelerated dynamic MRI with retrospective motion correction and outlier rejection.

    Science.gov (United States)

    van Amerom, Joshua F P; Lloyd, David F A; Price, Anthony N; Kuklisova Murgasova, Maria; Aljabar, Paul; Malik, Shaihan J; Lohezic, Maelene; Rutherford, Mary A; Pushparajah, Kuberan; Razavi, Reza; Hajnal, Joseph V

    2018-01-01

    Development of a MRI acquisition and reconstruction strategy to depict fetal cardiac anatomy in the presence of maternal and fetal motion. The proposed strategy involves i) acquisition and reconstruction of highly accelerated dynamic MRI, followed by image-based ii) cardiac synchronization, iii) motion correction, iv) outlier rejection, and finally v) cardiac cine reconstruction. Postprocessing entirely was automated, aside from a user-defined region of interest delineating the fetal heart. The method was evaluated in 30 mid- to late gestational age singleton pregnancies scanned without maternal breath-hold. The combination of complementary acquisition/reconstruction and correction/rejection steps in the pipeline served to improve the quality of the reconstructed 2D cine images, resulting in increased visibility of small, dynamic anatomical features. Artifact-free cine images successfully were produced in 36 of 39 acquired data sets; prolonged general fetal movements precluded processing of the remaining three data sets. The proposed method shows promise as a motion-tolerant framework to enable further detail in MRI studies of the fetal heart and great vessels. Processing data in image-space allowed for spatial and temporal operations to be applied to the fetal heart in isolation, separate from extraneous changes elsewhere in the field of view. Magn Reson Med 79:327-338, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine.

  10. Optimally combining dynamical decoupling and quantum error correction.

    Science.gov (United States)

    Paz-Silva, Gerardo A; Lidar, D A

    2013-01-01

    Quantum control and fault-tolerant quantum computing (FTQC) are two of the cornerstones on which the hope of realizing a large-scale quantum computer is pinned, yet only preliminary steps have been taken towards formalizing the interplay between them. Here we explore this interplay using the powerful strategy of dynamical decoupling (DD), and show how it can be seamlessly and optimally integrated with FTQC. To this end we show how to find the optimal decoupling generator set (DGS) for various subspaces relevant to FTQC, and how to simultaneously decouple them. We focus on stabilizer codes, which represent the largest contribution to the size of the DGS, showing that the intuitive choice comprising the stabilizers and logical operators of the code is in fact optimal, i.e., minimizes a natural cost function associated with the length of DD sequences. Our work brings hybrid DD-FTQC schemes, and their potentially considerable advantages, closer to realization.

  11. Meson exchange current corrections to magnetic moments in quantum hadro-dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Morse, T M; Price, C E; Shepard, J R [Colorado Univ., Boulder (USA). Dept. of Physics

    1990-11-15

    We have calculated pion exchange current corrections to the magnetic moments of closed shell {plus minus}1 particle nuclei near A=16 and 40 within the framework of quantum hadro-dynamics (QHD). We find that the correction is significant and that, in general, the agreement of the QHD isovector moments with experiment is worsened. Comparisons to previous non-relativistic calculations are also made. (orig.).

  12. Neural Network Based Real-time Correction of Transducer Dynamic Errors

    Science.gov (United States)

    Roj, J.

    2013-12-01

    In order to carry out real-time dynamic error correction of transducers described by a linear differential equation, a novel recurrent neural network was developed. The network structure is based on solving this equation with respect to the input quantity when using the state variables. It is shown that such a real-time correction can be carried out using simple linear perceptrons. Due to the use of a neural technique, knowledge of the dynamic parameters of the transducer is not necessary. Theoretical considerations are illustrated by the results of simulation studies performed for the modeled second order transducer. The most important properties of the neural dynamic error correction, when emphasizing the fundamental advantages and disadvantages, are discussed.

  13. A Phillips curve interpretation of error-correction models of the wage and price dynamics

    DEFF Research Database (Denmark)

    Harck, Søren H.

    -correction setting, which actually seems to capture the wage and price dynamics of many large- scale econometric models quite well, is fully compatible with the notion of an old-fashioned Phillips curve with finite slope. It is shown how the steady-state impact of various shocks to the model can be profitably...... This paper presents a model of employment, distribution and inflation in which a modern error correction specification of the nominal wage and price dynamics (referring to claims on income by workers and firms) occupies a prominent role. It is brought out, explicitly, how this rather typical error...

  14. A Phillips curve interpretation of error-correction models of the wage and price dynamics

    DEFF Research Database (Denmark)

    Harck, Søren H.

    2009-01-01

    -correction setting, which actually seems to capture the wage and price dynamics of many large- scale econometric models quite well, is fully compatible with the notion of an old-fashioned Phillips curve with finite slope. It is shown how the steady-state impact of various shocks to the model can be profitably......This paper presents a model of employment, distribution and inflation in which a modern error correction specification of the nominal wage and price dynamics (referring to claims on income by workers and firms) occupies a prominent role. It is brought out, explicitly, how this rather typical error...

  15. The generation algorithm of arbitrary polygon animation based on dynamic correction

    Directory of Open Access Journals (Sweden)

    Hou Ya Wei

    2016-01-01

    Full Text Available This paper, based on the key-frame polygon sequence, proposes a method that makes use of dynamic correction to develop continuous animation. Firstly we use quadratic Bezier curve to interpolate the corresponding sides vector of polygon sequence consecutive frame and realize the continuity of animation sequences. And then, according to Bezier curve characteristic, we conduct dynamic regulation to interpolation parameters and implement the changing smoothness. Meanwhile, we take use of Lagrange Multiplier Method to correct the polygon and close it. Finally, we provide the concrete algorithm flow and present numerical experiment results. The experiment results show that the algorithm acquires excellent effect.

  16. Error suppression and error correction in adiabatic quantum computation: non-equilibrium dynamics

    International Nuclear Information System (INIS)

    Sarovar, Mohan; Young, Kevin C

    2013-01-01

    While adiabatic quantum computing (AQC) has some robustness to noise and decoherence, it is widely believed that encoding, error suppression and error correction will be required to scale AQC to large problem sizes. Previous works have established at least two different techniques for error suppression in AQC. In this paper we derive a model for describing the dynamics of encoded AQC and show that previous constructions for error suppression can be unified with this dynamical model. In addition, the model clarifies the mechanisms of error suppression and allows the identification of its weaknesses. In the second half of the paper, we utilize our description of non-equilibrium dynamics in encoded AQC to construct methods for error correction in AQC by cooling local degrees of freedom (qubits). While this is shown to be possible in principle, we also identify the key challenge to this approach: the requirement of high-weight Hamiltonians. Finally, we use our dynamical model to perform a simplified thermal stability analysis of concatenated-stabilizer-code encoded many-body systems for AQC or quantum memories. This work is a companion paper to ‘Error suppression and error correction in adiabatic quantum computation: techniques and challenges (2013 Phys. Rev. X 3 041013)’, which provides a quantum information perspective on the techniques and limitations of error suppression and correction in AQC. In this paper we couch the same results within a dynamical framework, which allows for a detailed analysis of the non-equilibrium dynamics of error suppression and correction in encoded AQC. (paper)

  17. Short-term wind power combined forecasting based on error forecast correction

    International Nuclear Information System (INIS)

    Liang, Zhengtang; Liang, Jun; Wang, Chengfu; Dong, Xiaoming; Miao, Xiaofeng

    2016-01-01

    Highlights: • The correlation relationships of short-term wind power forecast errors are studied. • The correlation analysis method of the multi-step forecast errors is proposed. • A strategy selecting the input variables for the error forecast models is proposed. • Several novel combined models based on error forecast correction are proposed. • The combined models have improved the short-term wind power forecasting accuracy. - Abstract: With the increasing contribution of wind power to electric power grids, accurate forecasting of short-term wind power has become particularly valuable for wind farm operators, utility operators and customers. The aim of this study is to investigate the interdependence structure of errors in short-term wind power forecasting that is crucial for building error forecast models with regression learning algorithms to correct predictions and improve final forecasting accuracy. In this paper, several novel short-term wind power combined forecasting models based on error forecast correction are proposed in the one-step ahead, continuous and discontinuous multi-step ahead forecasting modes. First, the correlation relationships of forecast errors of the autoregressive model, the persistence method and the support vector machine model in various forecasting modes have been investigated to determine whether the error forecast models can be established by regression learning algorithms. Second, according to the results of the correlation analysis, the range of input variables is defined and an efficient strategy for selecting the input variables for the error forecast models is proposed. Finally, several combined forecasting models are proposed, in which the error forecast models are based on support vector machine/extreme learning machine, and correct the short-term wind power forecast values. The data collected from a wind farm in Hebei Province, China, are selected as a case study to demonstrate the effectiveness of the proposed

  18. A Hierarchical Bayes Error Correction Model to Explain Dynamic Effects of Price Changes

    NARCIS (Netherlands)

    D. Fok (Dennis); R. Paap (Richard); C. Horváth (Csilla); Ph.H.B.F. Franses (Philip Hans)

    2005-01-01

    textabstractThe authors put forward a sales response model to explain the differences in immediate and dynamic effects of promotional prices and regular prices on sales. The model consists of a vector autoregression rewritten in error-correction format which allows to disentangle the immediate

  19. Movement correction of the kidney in dynamic MRI scans using FFT phase difference movement detection

    NARCIS (Netherlands)

    Giele, ELW; de Priester, JA; Blom, JA; den Boer, JA; van Engelshoven, JMA; Hasman, A; Geerlings, M

    2001-01-01

    To measure cortical and medullary MR renograms, regions of interest (ROIs) are placed on the kidney in images acquired using dynamic MRI. Since native kidneys move with breathing, and breath-holding techniques are not feasible, movement correction is necessary. In this contribution we compare three

  20. Correction of the dynamic response of the ''Gamma thermometers'' using a digital filter

    International Nuclear Information System (INIS)

    Jacquot, J.P.; Lobert, J.P.

    1985-01-01

    The ''gamma thermometer'' is a sensor used to measure on line the local power inside a PWR nuclear reactor. During transients, this sensor based on thermal exchanges, obes not give a fast response. This paper describes a microprocessor device that allows using a digital filtering technique, a correction of the dynamic response [fr

  1. The dynamics of entry, exit and profitability: an error correction approach for the retail industry

    NARCIS (Netherlands)

    M.A. Carree (Martin); A.R. Thurik (Roy)

    1994-01-01

    textabstractWe develop a two equation error correction model to investigate determinants of and dynamic interaction between changes in profits and number of firms in retailing. An explicit distinction is made between the effects of actual competition among incumbants, new firms competition and

  2. How long-term dynamics of sediment subduction controls short-term dynamics of seismicity

    Science.gov (United States)

    Brizzi, S.; van Zelst, I.; van Dinther, Y.; Funiciello, F.; Corbi, F.

    2017-12-01

    Most of the world's greatest earthquakes occur along the subduction megathrust. Weak and porous sediments have been suggested to homogenize the plate interface and thereby promote lateral rupture propagation and great earthquakes. However, the importance of sediment thickness, let alone their physical role, is not yet unequivocally established. Based on a multivariate statistical analysis of a global database of 62 subduction segments, we confirm that sediment thickness is one of the key parameters controlling the maximum magnitude a megathrust can generate. Moreover, Monte Carlo simulations highlighted that the occurrence of great earthquakes on sediment-rich subduction segments is very unlikely (p-value≪0.05) related to pure chance. To understand how sediments in the subduction channel regulate earthquake size, this study extends and demystifies multivariate, spatiotemporally limited data through numerical modeling. We use the 2D Seismo-Thermo-Mechanical modeling approach to simulate both the long- and short-term dynamics of subduction and related seismogenesis (van Dinther et al., JGR, 2013). These models solve for the conservation of mass, momentum and energy using a visco-elasto-plastic rheology with rate-dependent friction. Results show that subducted sediments have a strong influence on the long-term evolution of the convergent margin. Increasing the sediment thickness on the incoming plate from 0 to 6 km causes a decrease of slab dip from 23° to 10°. This, in addition to increased radiogenic heating, extends isotherms, thereby widening the seismogenic portion of the megathrust from 80 to 150 km. Consequently, over tens of thousands of years, we observe that the maximum moment magnitude of megathrust earthquakes increases from 8.2 to 9.2 for these shallower and warmer interfaces. In addition, we observe more and larger splay faults, which could enhance vertical seafloor displacements. These results highlight the primary role of subducted sediments in

  3. Long-Term Dynamics of Autonomous Fractional Differential Equations

    Science.gov (United States)

    Liu, Tao; Xu, Wei; Xu, Yong; Han, Qun

    This paper aims to investigate long-term dynamic behaviors of autonomous fractional differential equations with effective numerical method. The long-term dynamic behaviors predict where systems are heading after long-term evolution. We make some modification and transplant cell mapping methods to autonomous fractional differential equations. The mapping time duration of cell mapping is enlarged to deal with the long memory effect. Three illustrative examples, i.e. fractional Lotka-Volterra equation, fractional van der Pol oscillator and fractional Duffing equation, are studied with our revised generalized cell mapping method. We obtain long-term dynamics, such as attractors, basins of attraction, and saddles. Compared with some existing stability and numerical results, the validity of our method is verified. Furthermore, we find that the fractional order has its effect on the long-term dynamics of autonomous fractional differential equations.

  4. A novel energy conversion based method for velocity correction in molecular dynamics simulations

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Hanhui [School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027 (China); Collaborative Innovation Center of Advanced Aero-Engine, Hangzhou 310027 (China); Liu, Ningning [School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027 (China); Ku, Xiaoke, E-mail: xiaokeku@zju.edu.cn [School of Aeronautics and Astronautics, Zhejiang University, Hangzhou 310027 (China); Fan, Jianren [State Key Laboratory of Clean Energy Utilization, Zhejiang University, Hangzhou 310027 (China)

    2017-05-01

    Molecular dynamics (MD) simulation has become an important tool for studying micro- or nano-scale dynamics and the statistical properties of fluids and solids. In MD simulations, there are mainly two approaches: equilibrium and non-equilibrium molecular dynamics (EMD and NEMD). In this paper, a new energy conversion based correction (ECBC) method for MD is developed. Unlike the traditional systematic correction based on macroscopic parameters, the ECBC method is developed strictly based on the physical interaction processes between the pair of molecules or atoms. The developed ECBC method can apply to EMD and NEMD directly. While using MD with this method, the difference between the EMD and NEMD is eliminated, and no macroscopic parameters such as external imposed potentials or coefficients are needed. With this method, many limits of using MD are lifted. The application scope of MD is greatly extended.

  5. A novel energy conversion based method for velocity correction in molecular dynamics simulations

    International Nuclear Information System (INIS)

    Jin, Hanhui; Liu, Ningning; Ku, Xiaoke; Fan, Jianren

    2017-01-01

    Molecular dynamics (MD) simulation has become an important tool for studying micro- or nano-scale dynamics and the statistical properties of fluids and solids. In MD simulations, there are mainly two approaches: equilibrium and non-equilibrium molecular dynamics (EMD and NEMD). In this paper, a new energy conversion based correction (ECBC) method for MD is developed. Unlike the traditional systematic correction based on macroscopic parameters, the ECBC method is developed strictly based on the physical interaction processes between the pair of molecules or atoms. The developed ECBC method can apply to EMD and NEMD directly. While using MD with this method, the difference between the EMD and NEMD is eliminated, and no macroscopic parameters such as external imposed potentials or coefficients are needed. With this method, many limits of using MD are lifted. The application scope of MD is greatly extended.

  6. Effect of correction of aberration dynamics on chaos in human ocular accommodation.

    Science.gov (United States)

    Hampson, Karen M; Cufflin, Matthew P; Mallen, Edward A H

    2013-11-15

    We used adaptive optics to determine the effect of monochromatic aberration dynamics on the level of chaos in the accommodation control system. Four participants viewed a stationary target while the dynamics of their aberrations were either left uncorrected, defocus was corrected, or all aberrations except defocus were corrected. Chaos theory analysis was used to discern changes in the accommodative microfluctuations. We found a statistically significant reduction in the chaotic nature of the accommodation microfluctuations during correction of defocus, but not when all aberrations except defocus were corrected. The Lyapunov exponent decreased from 0.71 ± 0.07 D/s (baseline) to 0.55 ± 0.03 D/s (correction of defocus fluctuations). As the reduction of chaos in physiological signals is indicative of stress to the system, the results indicate that for the participants included in this study, fluctuations in defocus have a more profound effect than those of the other aberrations. There were no changes in the power spectrum between experimental conditions. Hence chaos theory analysis is a more subtle marker of changes in the accommodation control system and will be of value in the study of myopia onset and progression.

  7. The Effect of Dynamic Written Corrective Feedback on Iranian Elementary Learners’ Writing

    Directory of Open Access Journals (Sweden)

    Amaneh Kamalian

    2014-09-01

    Full Text Available Error correction is probably the most widely used technique for responding to students’ writing. Although many studies have attempted to investigate the efficacy of providing error correction through different types of written corrective feedback (WCF, there has been relatively little research on any one new approach to writing pedagogy in foreign language learning which is called dynamic WCF. The purpose of the current research was to test the effect of WCF on the improvement of writing abilities of EFL learners. Two groups of EFL students who were learning English as a foreign language participated in this study. Both groups (A and B were given treatments. Core components of the treatment included having the students to write a composition every session (twice a week and the teacher providing the students with feedbacks (dynamic WCF or direct WCF on their writing tasks. Group A (n=24 was instructed through dynamic WCF because it was intended to improve L2 writing ability in general by raising linguistic awareness of learners through the error corrections performed by the teacher.  On the other hand, group B (n= 22 received direct WCF on their writings. Four essential characteristics were taken into consideration for the error correction, i.e. feedback needed to be manageable, meaningful, timely and constant. The data obtained for Group A and Group B was analyzed using paired sample test and the results indicated that both groups had improved on their writing abilities. Also, administrating an independent sample T-test the findings revealed that Group A which received dynamic WCF could outperform Group B.

  8. Automated movement correction for dynamic PET/CT images: evaluation with phantom and patient data.

    Science.gov (United States)

    Ye, Hu; Wong, Koon-Pong; Wardak, Mirwais; Dahlbom, Magnus; Kepe, Vladimir; Barrio, Jorge R; Nelson, Linda D; Small, Gary W; Huang, Sung-Cheng

    2014-01-01

    Head movement during a dynamic brain PET/CT imaging results in mismatch between CT and dynamic PET images. It can cause artifacts in CT-based attenuation corrected PET images, thus affecting both the qualitative and quantitative aspects of the dynamic PET images and the derived parametric images. In this study, we developed an automated retrospective image-based movement correction (MC) procedure. The MC method first registered the CT image to each dynamic PET frames, then re-reconstructed the PET frames with CT-based attenuation correction, and finally re-aligned all the PET frames to the same position. We evaluated the MC method's performance on the Hoffman phantom and dynamic FDDNP and FDG PET/CT images of patients with neurodegenerative disease or with poor compliance. Dynamic FDDNP PET/CT images (65 min) were obtained from 12 patients and dynamic FDG PET/CT images (60 min) were obtained from 6 patients. Logan analysis with cerebellum as the reference region was used to generate regional distribution volume ratio (DVR) for FDDNP scan before and after MC. For FDG studies, the image derived input function was used to generate parametric image of FDG uptake constant (Ki) before and after MC. Phantom study showed high accuracy of registration between PET and CT and improved PET images after MC. In patient study, head movement was observed in all subjects, especially in late PET frames with an average displacement of 6.92 mm. The z-direction translation (average maximum = 5.32 mm) and x-axis rotation (average maximum = 5.19 degrees) occurred most frequently. Image artifacts were significantly diminished after MC. There were significant differences (Pdynamic brain FDDNP and FDG PET/CT scans could improve the qualitative and quantitative aspects of images of both tracers.

  9. Short-Term Wind Speed Hybrid Forecasting Model Based on Bias Correcting Study and Its Application

    OpenAIRE

    Mingfei Niu; Shaolong Sun; Jie Wu; Yuanlei Zhang

    2015-01-01

    The accuracy of wind speed forecasting is becoming increasingly important to improve and optimize renewable wind power generation. In particular, reliable short-term wind speed forecasting can enable model predictive control of wind turbines and real-time optimization of wind farm operation. However, due to the strong stochastic nature and dynamic uncertainty of wind speed, the forecasting of wind speed data using different patterns is difficult. This paper proposes a novel combination bias c...

  10. Shepherd's Crook Deformity of Polyostotic Fibrous Dysplasia Treated with Corrective Osteotomy and Dynamic Hip Screw

    Directory of Open Access Journals (Sweden)

    Wei-Jen Chen

    2005-07-01

    Full Text Available Fibrous dysplasia, a condition in which the skeleton fails to develop normally, is characterized by fibroblastic stroma and immature bone. Bowing of the long bones occurs frequently in the polyostotic form, and stress fractures often result. Shepherd's crook deformity is a characteristic feature of fibrous dysplasia. The goal of its treatment is to obtain normal walking ability and relieve pain due to pathologic fracture secondary to the deformity; however, correction of the deformity is a surgical challenge. We present 2 cases of shepherd's crook deformity treated with corrective osteotomy and a dynamic hip screw. Both cases showed good bone healing and no recurrent deformity. The gross deformities were corrected, and both patients were pain-free after operation.

  11. Local-field correction in the lattice dynamics of b.b.c. transition metals

    International Nuclear Information System (INIS)

    Onwuagba, B.N.

    1984-01-01

    It is shown that the off-diagonal components of the inverse dielectric matrix which determine the local-field correction associated with s-d interactions, make contributions to the dynamical matrix for phonon dispersion in the body-centred cubic transition metals V, Nb and Ta which tend to cancel the Born-Mayer contribution, just as the diagonal components of the inverse dielectric matrix tend to cancel or screen the long-range (Coulombic) contribution. Numerical calculations show that the cancellation of the Born-Mayer contribution to the dynamical matrix by the local-field correction is such that the effective short-range interatomic potential turns out to be attractive rather than repulsive in these metals and accounts for some peculiar shapes of the major soft modes observed in these metals

  12. Correction for dynamic bias error in transmission measurements of void fraction

    International Nuclear Information System (INIS)

    Andersson, P.; Sundén, E. Andersson; Svärd, S. Jacobsson; Sjöstrand, H.

    2012-01-01

    Dynamic bias errors occur in transmission measurements, such as X-ray, gamma, or neutron radiography or tomography. This is observed when the properties of the object are not stationary in time and its average properties are assessed. The nonlinear measurement response to changes in transmission within the time scale of the measurement implies a bias, which can be difficult to correct for. A typical example is the tomographic or radiographic mapping of void content in dynamic two-phase flow systems. In this work, the dynamic bias error is described and a method to make a first-order correction is derived. A prerequisite for this method is variance estimates of the system dynamics, which can be obtained using high-speed, time-resolved data acquisition. However, in the absence of such acquisition, a priori knowledge might be used to substitute the time resolved data. Using synthetic data, a void fraction measurement case study has been simulated to demonstrate the performance of the suggested method. The transmission length of the radiation in the object under study and the type of fluctuation of the void fraction have been varied. Significant decreases in the dynamic bias error were achieved to the expense of marginal decreases in precision.

  13. Aphakia correction with retropupillary fixated iris-claw lens (Artisan – long-term results

    Directory of Open Access Journals (Sweden)

    Schallenberg M

    2013-12-01

    Full Text Available Maurice Schallenberg,1,2 Dirk Dekowski,1 Angela Hahn,1 Thomas Laube,1,3 Klaus-Peter Steuhl,1 Daniel Meller11Department of Ophthalmology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany; 2HELIOS Klinikum Wuppertal, Wuppertal, Germany; 3Zentrum für Augenheilkunde PD Dr Laube, Düsseldorf, GermanyPurpose: To evaluate the technique, safety, and efficacy of the retropupillary implantation of iris-claw intraocular lenses in a long-term follow-up study.Patients and methods: This retrospective study included 31 eyes of 31 patients who underwent an Artisan aphakic intraocular lens implantation between January 2006 and February 2011 at the University Hospital Essen, Essen, Germany and at the Zentrum für Augenheilkunde PD Dr Laube, Düsseldorf, Germany. Preoperative data collected included demographics, etiology of aphakia, previous surgeries, preoperative eye pathology, intraocular pressure, clinical signs of endothelial cell loss, and best corrected visual acuity. Operative data and postoperative outcomes included the best corrected visual acuity, lens position, intraocular pressure, pigment dispersion, clinical signs of endothelial cell loss, development of macular edema, and other complications.Results: Thirty-one patients were included. The mean follow-up was 25.2 months (range: 4–48 months. The mean best corrected visual acuity postoperatively was 0.64 logarithm of the minimum angle of resolution (logMAR and varied from 0 logMAR to 3 logMAR. Some patients had a low visual acuity preoperatively because of preoperative eye pathologies. In 22 patients the visual acuity improved, in two patients the visual acuity remained unchanged, and seven patients showed a decreased visual acuity. Complications were peaked pupils (n=10 and retinal detachment in one case. Four patients showed an iris atrophy and high intraocular pressure was observed only in one patient. Subluxation of the intraocular lens, endothelial cell loss, and

  14. Dynamic stability control in forward falls: postural corrections after muscle fatigue in young and older adults.

    Science.gov (United States)

    Mademli, Lida; Arampatzis, Adamantios; Karamanidis, Kiros

    2008-06-01

    Many studies report that muscle strength loss may alter the human system's capacity to generate rapid force for balance corrections after perturbations, leading to deficient recovery behaviours. Yet little is known regarding the effect of modifications in the neuromuscular system induced by fatigue on dynamic stability control during postural perturbations. This study investigates the effect of muscle strength decline induced by fatiguing contractions on the dynamic stability control of young and older adults during forward falls. Eleven young and eleven older male adults had to regain balance after sudden falls before and after submaximal fatiguing knee extension-flexion contractions. Young subjects had a higher margin of stability than older ones before and after the fatiguing task. This reflects their enhanced ability in using mechanisms for maintaining dynamic stability (i.e. a greater base of support). The margin of stability, the boundary of the base of support and the position of the extrapolated centre of mass, remained unaffected by the reduction in muscle strength induced by the fatiguing contractions, indicating an appropriate adjustment of the motor commands to compensate the deficit in muscle strength. Both young and older adults were able to counteract the decreased horizontal ground reaction forces after the fatiguing task by flexing their knee to a greater extent, leading to similar decreases in the horizontal velocity of centre of mass as in the pre fatigue condition. The results demonstrate the ability of the central nervous system to rapidly modify the execution of postural corrections including mechanisms for maintaining dynamic stability.

  15. Modeling long-term dynamics of electricity markets

    International Nuclear Information System (INIS)

    Olsina, Fernando; Garces, Francisco; Haubrich, H.-J.

    2006-01-01

    In the last decade, many countries have restructured their electricity industries by introducing competition in their power generation sectors. Although some restructuring has been regarded as successful, the short experience accumulated with liberalized power markets does not allow making any founded assertion about their long-term behavior. Long-term prices and long-term supply reliability are now center of interest. This concerns firms considering investments in generation capacity and regulatory authorities interested in assuring the long-term supply adequacy and the stability of power markets. In order to gain significant insight into the long-term behavior of liberalized power markets, in this paper, a simulation model based on system dynamics is proposed and the underlying mathematical formulations extensively discussed. Unlike classical market models based on the assumption that market outcomes replicate the results of a centrally made optimization, the approach presented here focuses on replicating the system structure of power markets and the logic of relationships among system components in order to derive its dynamical response. The simulations suggest that there might be serious problems to adjust early enough the generation capacity necessary to maintain stable reserve margins, and consequently, stable long-term price levels. Because of feedback loops embedded in the structure of power markets and the existence of some time lags, the long-term market development might exhibit a quite volatile behavior. By varying some exogenous inputs, a sensitivity analysis is carried out to assess the influence of these factors on the long-run market dynamics

  16. Event-by-Event Continuous Respiratory Motion Correction for Dynamic PET Imaging.

    Science.gov (United States)

    Yu, Yunhan; Chan, Chung; Ma, Tianyu; Liu, Yaqiang; Gallezot, Jean-Dominique; Naganawa, Mika; Kelada, Olivia J; Germino, Mary; Sinusas, Albert J; Carson, Richard E; Liu, Chi

    2016-07-01

    Existing respiratory motion-correction methods are applied only to static PET imaging. We have previously developed an event-by-event respiratory motion-correction method with correlations between internal organ motion and external respiratory signals (INTEX). This method is uniquely appropriate for dynamic imaging because it corrects motion for each time point. In this study, we applied INTEX to human dynamic PET studies with various tracers and investigated the impact on kinetic parameter estimation. The use of 3 tracers-a myocardial perfusion tracer, (82)Rb (n = 7); a pancreatic β-cell tracer, (18)F-FP(+)DTBZ (n = 4); and a tumor hypoxia tracer, (18)F-fluoromisonidazole ((18)F-FMISO) (n = 1)-was investigated in a study of 12 human subjects. Both rest and stress studies were performed for (82)Rb. The Anzai belt system was used to record respiratory motion. Three-dimensional internal organ motion in high temporal resolution was calculated by INTEX to guide event-by-event respiratory motion correction of target organs in each dynamic frame. Time-activity curves of regions of interest drawn based on end-expiration PET images were obtained. For (82)Rb studies, K1 was obtained with a 1-tissue model using a left-ventricle input function. Rest-stress myocardial blood flow (MBF) and coronary flow reserve (CFR) were determined. For (18)F-FP(+)DTBZ studies, the total volume of distribution was estimated with arterial input functions using the multilinear analysis 1 method. For the (18)F-FMISO study, the net uptake rate Ki was obtained with a 2-tissue irreversible model using a left-ventricle input function. All parameters were compared with the values derived without motion correction. With INTEX, K1 and MBF increased by 10% ± 12% and 15% ± 19%, respectively, for (82)Rb stress studies. CFR increased by 19% ± 21%. For studies with motion amplitudes greater than 8 mm (n = 3), K1, MBF, and CFR increased by 20% ± 12%, 30% ± 20%, and 34% ± 23%, respectively. For (82)Rb

  17. Direct Parametric Reconstruction With Joint Motion Estimation/Correction for Dynamic Brain PET Data.

    Science.gov (United States)

    Jiao, Jieqing; Bousse, Alexandre; Thielemans, Kris; Burgos, Ninon; Weston, Philip S J; Schott, Jonathan M; Atkinson, David; Arridge, Simon R; Hutton, Brian F; Markiewicz, Pawel; Ourselin, Sebastien

    2017-01-01

    Direct reconstruction of parametric images from raw photon counts has been shown to improve the quantitative analysis of dynamic positron emission tomography (PET) data. However it suffers from subject motion which is inevitable during the typical acquisition time of 1-2 hours. In this work we propose a framework to jointly estimate subject head motion and reconstruct the motion-corrected parametric images directly from raw PET data, so that the effects of distorted tissue-to-voxel mapping due to subject motion can be reduced in reconstructing the parametric images with motion-compensated attenuation correction and spatially aligned temporal PET data. The proposed approach is formulated within the maximum likelihood framework, and efficient solutions are derived for estimating subject motion and kinetic parameters from raw PET photon count data. Results from evaluations on simulated [ 11 C]raclopride data using the Zubal brain phantom and real clinical [ 18 F]florbetapir data of a patient with Alzheimer's disease show that the proposed joint direct parametric reconstruction motion correction approach can improve the accuracy of quantifying dynamic PET data with large subject motion.

  18. Quantum corrections to scalar field dynamics in a slow-roll space-time

    Energy Technology Data Exchange (ETDEWEB)

    Herranen, Matti [Niels Bohr International Academy and Discovery Center, Niels Bohr Institute,University of Copenhagen,Blegdamsvej 17, 2100 Copenhagen (Denmark); Markkanen, Tommi [Helsinki Institute of Physics and Department of Physics,P.O. Box 64, FI-00014, University of Helsinki (Finland); Tranberg, Anders [Faculty of Science and Technology, University of Stavanger, 4036 Stavanger (Norway)

    2014-05-07

    We consider the dynamics of a quantum scalar field in the background of a slow-roll inflating Universe. We compute the one-loop quantum corrections to the field and Friedmann equation of motion, in both a 1PI and a 2PI expansion, to leading order in slow-roll. Generalizing the works of http://dx.doi.org/10.1016/j.nuclphysb.2006.04.029, http://dx.doi.org/10.1103/PhysRevLett.107.191103, http://dx.doi.org/10.1103/PhysRevD.76.103507 and http://dx.doi.org/10.1016/j.nuclphysb.2006.04.010, we then solve these equations to compute the effect on the primordial power spectrum, for the case of a self-interacting inflaton and a self-interacting spectator field. We find that for the inflaton the corrections are negligible due to the smallness of the coupling constant despite the large IR enhancement of the loop contributions. For a curvaton scenario, on the other hand, we find tension in using the 1PI loop corrections, which may indicate that the quantum corrections could be non-perturbatively large in this case, thus requiring resummation.

  19. Long-term treatment with calcium-alpha-ketoglutarate corrects secondary hyperparathyroidism.

    Science.gov (United States)

    Zimmermann, E; Wassmer, S; Steudle, V

    1996-01-01

    Calcium-alpha-ketoglutarate (Ca-ket) is known as a highly effective phosphate (P) binder in hemodialysis (HD) patients. In addition, alpha-ketoglutarate has been shown to improve metabolic alterations. We investigated the effect of long-term P-binding therapy with Ca-ket to determine whether P accumulation is the main reason of secondary hyperparathyroidism (HPT) in HD patients or not. Ca-ket was prescribed to 14 HD patients as a soluble preparation in a mean dosage of 4.5 g/day (0.975 g elemental Ca) for a period of 36 months. Serum P continuously dropped from prestudy 2.6 +/- 0.1 (mean +/- SEM) to 1.9 +/- 0.07 mmol/l (p < 0.001), whereas serum Ca increased from 2.2 +/- 0.1 to 2.47 +/- 0.08 mmol/l (p < 0.05). Thus, Ca/P ratio in serum converted significantly from 0.91 +/- 0.02 (prestudy) to 1.28 +/- 0.01 (p < 0.001). Intact parathyroid hormone (iPTH) continuously normalized in all patients from 29 +/- 5 to 8 +/- 2 pmol/l (p < 0.001). The present data show that long-term treatment with Ca-ket normalizes secondary HPT by simultaneously P binding and correcting Ca/P ratio in serum without vitamin D treatment.

  20. Correction of Dynamic Characteristics of SAR Cryogenic GTE on Consumption of Gasified Fuel

    Science.gov (United States)

    Bukin, V. A.; Gimadiev, A. G.; Gangisetty, G.

    2018-01-01

    When the gas turbine engines (GTE) NK-88 were developed for liquid hydrogen and NK-89 for liquefied natural gas, performance of the systems with a turbo-pump unitary was improved and its proved without direct regulation of the flow of a cryogenic fuel, which was supplied by a centrifugal pump of the turbo-pump unit (TPU) Command from the “kerosene” system. Such type of the automatic control system (SAR) has the property of partial “neutralization” of the delay caused by gasification of the fuel. This does not require any measurements in the cryogenic medium, and the failure of the centrifugal cryogenic pump does not lead to engine failure. On the other hand, the system without direct regulation of the flow of cryogenic fuel has complex internal dynamic connections, their properties are determined by the characteristics of the incoming units and assemblies, and it is difficult to maintain accurate the maximum boundary level and minimum fuel consumption due to the influence of a booster pressure change. Direct regulation of the consumption of cryogenic fuel (prior to its gasification) is the preferred solution, since for using traditional liquid and gaseous fuels this is the main and proven method. The scheme of correction of dynamic characteristics of a single-loop SAR GTE for the consumption of a liquefied cryogenic fuel with a flow rate correction in its gasified state, which ensures the dynamic properties of the system is not worse than for NK-88 and NK-89 engines.

  1. Dynamic Black-Level Correction and Artifact Flagging for Kepler Pixel Time Series

    Science.gov (United States)

    Kolodziejczak, J. J.; Clarke, B. D.; Caldwell, D. A.

    2011-01-01

    Methods applied to the calibration stage of Kepler pipeline data processing [1] (CAL) do not currently use all of the information available to identify and correct several instrument-induced artifacts. These include time-varying crosstalk from the fine guidance sensor (FGS) clock signals, and manifestations of drifting moire pattern as locally correlated nonstationary noise, and rolling bands in the images which find their way into the time series [2], [3]. As the Kepler Mission continues to improve the fidelity of its science data products, we are evaluating the benefits of adding pipeline steps to more completely model and dynamically correct the FGS crosstalk, then use the residuals from these model fits to detect and flag spatial regions and time intervals of strong time-varying black-level which may complicate later processing or lead to misinterpretation of instrument behavior as stellar activity.

  2. Simulation of dynamic pile-up corrections in the ATLAS level-1 calorimeter trigger

    Energy Technology Data Exchange (ETDEWEB)

    Narrias-Villar, Daniel; Wessels, Martin; Brandt, Oleg [Heidelberg University, Heidelberg (Germany)

    2015-07-01

    The Level-1 Calorimeter Trigger is a crucial part of the ATLAS trigger effort to select only relevant physics events out of the large number of interactions at the LHC. In Run II, in which the LHC will double the centre-of-mass energy and further increase the instantaneous luminosity, pile-up is a limiting key factor for triggering and reconstruction of relevant events. The upgraded L1Calo Multi-Chip-Modules (nMCM) will address this problem by applying dynamic pile-up corrections in real-time, of which a precise simulation is crucial for physics analysis. Therefore pile-up effects are studied in order to provide a predictable parametrised baseline correction for the Monte Carlo simulation. Physics validation plots, such as trigger rates and turn-on curves are laid out.

  3. Simulation of long-term dynamic behavior of runaway electrons

    International Nuclear Information System (INIS)

    Wang Yulei; Liu Jian; Zhang Ruili; He Yang

    2015-01-01

    The secular dynamics of runaway electrons in Tokamak electromagnetic field is studied. The radiation effect is added into a relativistic volume-preserving algorithm to gain long-term stability of calculation. The results shows that the method we used is able to reveal the behavior of a runaway electron in configuration space. (author)

  4. An Improved Dynamical Downscaling Method with GCM Bias Corrections and Its Validation with 30 Years of Climate Simulations

    KAUST Repository

    Xu, Zhongfeng; Yang, Zong-Liang

    2012-01-01

    An improved dynamical downscaling method (IDD) with general circulation model (GCM) bias corrections is developed and assessed over North America. A set of regional climate simulations is performed with the Weather Research and Forecasting Model

  5. Long Term Incentives for Residential Customers Using Dynamic Tariff

    DEFF Research Database (Denmark)

    Huang, Shaojun; Wu, Qiuwei; Nielsen, Arne Hejde

    2015-01-01

    This paper reviews several grid tariff schemes, including flat tariff, time-of-use, time-varying tariff, demand charge and dynamic tariff (DT), from the perspective of the long term incentives. The long term incentives can motivate the owners of flexible demands to change their energy consumption...... behavior in such a way that the power system operation issues, such as system balance and congestion, can be alleviated. From the comparison study, including analysis and case study, the DT scheme outperforms the other tariff schemes in terms of cost saving and network operation condition improving....

  6. Quantum corrected Langevin dynamics for adsorbates on metal surfaces interacting with hot electrons

    DEFF Research Database (Denmark)

    Olsen, Thomas; Schiøtz, Jakob

    2010-01-01

    We investigate the importance of including quantized initial conditions in Langevin dynamics for adsorbates interacting with a thermal reservoir of electrons. For quadratic potentials the time evolution is exactly described by a classical Langevin equation and it is shown how to rigorously obtain...... quantum mechanical probabilities from the classical phase space distributions resulting from the dynamics. At short time scales, classical and quasiclassical initial conditions lead to wrong results and only correctly quantized initial conditions give a close agreement with an inherently quantum...... mechanical master equation approach. With CO on Cu(100) as an example, we demonstrate the effect for a system with ab initio frictional tensor and potential energy surfaces and show that quantizing the initial conditions can have a large impact on both the desorption probability and the distribution...

  7. Lattice constants of pure methane and carbon dioxide hydrates at low temperatures. Implementing quantum corrections to classical molecular dynamics studies

    Energy Technology Data Exchange (ETDEWEB)

    Costandy, Joseph; Michalis, Vasileios K.; Economou, Ioannis G., E-mail: i.tsimpanogiannis@qatar.tamu.edu, E-mail: ioannis.economou@qatar.tamu.edu [Chemical Engineering Program, Texas A& M University at Qatar, P.O. Box 23874, Doha (Qatar); Tsimpanogiannis, Ioannis N., E-mail: i.tsimpanogiannis@qatar.tamu.edu, E-mail: ioannis.economou@qatar.tamu.edu [Chemical Engineering Program, Texas A& M University at Qatar, P.O. Box 23874, Doha (Qatar); Environmental Research Laboratory, National Center for Scientific Research NCSR “Demokritos,” 15310 Aghia Paraskevi, Attikis (Greece); Stubos, Athanassios K. [Environmental Research Laboratory, National Center for Scientific Research NCSR “Demokritos,” 15310 Aghia Paraskevi, Attikis (Greece)

    2016-03-28

    We introduce a simple correction to the calculation of the lattice constants of fully occupied structure sI methane or carbon dioxide pure hydrates that are obtained from classical molecular dynamics simulations using the TIP4PQ/2005 water force field. The obtained corrected lattice constants are subsequently used in order to obtain isobaric thermal expansion coefficients of the pure gas hydrates that exhibit a trend that is significantly closer to the experimental behavior than previously reported classical molecular dynamics studies.

  8. Impact of respiratory motion correction and spatial resolution on lesion detection in PET: a simulation study based on real MR dynamic data

    Science.gov (United States)

    Polycarpou, Irene; Tsoumpas, Charalampos; King, Andrew P.; Marsden, Paul K.

    2014-02-01

    The aim of this study is to investigate the impact of respiratory motion correction and spatial resolution on lesion detectability in PET as a function of lesion size and tracer uptake. Real respiratory signals describing different breathing types are combined with a motion model formed from real dynamic MR data to simulate multiple dynamic PET datasets acquired from a continuously moving subject. Lung and liver lesions were simulated with diameters ranging from 6 to 12 mm and lesion to background ratio ranging from 3:1 to 6:1. Projection data for 6 and 3 mm PET scanner resolution were generated using analytic simulations and reconstructed without and with motion correction. Motion correction was achieved using motion compensated image reconstruction. The detectability performance was quantified by a receiver operating characteristic (ROC) analysis obtained using a channelized Hotelling observer and the area under the ROC curve (AUC) was calculated as the figure of merit. The results indicate that respiratory motion limits the detectability of lung and liver lesions, depending on the variation of the breathing cycle length and amplitude. Patients with large quiescent periods had a greater AUC than patients with regular breathing cycles and patients with long-term variability in respiratory cycle or higher motion amplitude. In addition, small (less than 10 mm diameter) or low contrast (3:1) lesions showed the greatest improvement in AUC as a result of applying motion correction. In particular, after applying motion correction the AUC is improved by up to 42% with current PET resolution (i.e. 6 mm) and up to 51% for higher PET resolution (i.e. 3 mm). Finally, the benefit of increasing the scanner resolution is small unless motion correction is applied. This investigation indicates high impact of respiratory motion correction on lesion detectability in PET and highlights the importance of motion correction in order to benefit from the increased resolution of future

  9. Impact of respiratory motion correction and spatial resolution on lesion detection in PET: a simulation study based on real MR dynamic data

    International Nuclear Information System (INIS)

    Polycarpou, Irene; Tsoumpas, Charalampos; King, Andrew P; Marsden, Paul K

    2014-01-01

    The aim of this study is to investigate the impact of respiratory motion correction and spatial resolution on lesion detectability in PET as a function of lesion size and tracer uptake. Real respiratory signals describing different breathing types are combined with a motion model formed from real dynamic MR data to simulate multiple dynamic PET datasets acquired from a continuously moving subject. Lung and liver lesions were simulated with diameters ranging from 6 to 12 mm and lesion to background ratio ranging from 3:1 to 6:1. Projection data for 6 and 3 mm PET scanner resolution were generated using analytic simulations and reconstructed without and with motion correction. Motion correction was achieved using motion compensated image reconstruction. The detectability performance was quantified by a receiver operating characteristic (ROC) analysis obtained using a channelized Hotelling observer and the area under the ROC curve (AUC) was calculated as the figure of merit. The results indicate that respiratory motion limits the detectability of lung and liver lesions, depending on the variation of the breathing cycle length and amplitude. Patients with large quiescent periods had a greater AUC than patients with regular breathing cycles and patients with long-term variability in respiratory cycle or higher motion amplitude. In addition, small (less than 10 mm diameter) or low contrast (3:1) lesions showed the greatest improvement in AUC as a result of applying motion correction. In particular, after applying motion correction the AUC is improved by up to 42% with current PET resolution (i.e. 6 mm) and up to 51% for higher PET resolution (i.e. 3 mm). Finally, the benefit of increasing the scanner resolution is small unless motion correction is applied. This investigation indicates high impact of respiratory motion correction on lesion detectability in PET and highlights the importance of motion correction in order to benefit from the increased resolution of future

  10. Moduli stabilization and uplifting with dynamically generated F-terms

    International Nuclear Information System (INIS)

    Dudas, Emilian; Papineau, Chloe; Pokorski, Stefan

    2007-01-01

    We use the F-term dynamical supersymmetry breaking models with metastable vacua in order to uplift the vacuum energy in the KKLT moduli stabilization scenario. The main advantage compared to earlier proposals is the manifest supersymmetric treatment and the natural coexistence of a TeV gravitino mass with a zero cosmological constant. We argue that it is generically difficult to avoid anti de-Sitter supersymmetric minima, however the tunneling rate from the metastable vacuum with zero vacuum energy towards them can be very suppressed. We briefly comment on the properties of the induced soft terms in the observable sector

  11. Moduli stabilization and uplifting with dynamically generated F-terms

    Energy Technology Data Exchange (ETDEWEB)

    Dudas, Emilian [CERN Theory Division, CH-1211, Geneva 23 (Switzerland); Papineau, Chloe [CPhT, Ecole Polytechnique, F-91128 Palaiseau Cedex (France); Pokorski, Stefan [Institute of Theoretical Physics, Univ. of Warsaw, 00-681 Warsaw (Poland)

    2007-02-15

    We use the F-term dynamical supersymmetry breaking models with metastable vacua in order to uplift the vacuum energy in the KKLT moduli stabilization scenario. The main advantage compared to earlier proposals is the manifest supersymmetric treatment and the natural coexistence of a TeV gravitino mass with a zero cosmological constant. We argue that it is generically difficult to avoid anti de-Sitter supersymmetric minima, however the tunneling rate from the metastable vacuum with zero vacuum energy towards them can be very suppressed. We briefly comment on the properties of the induced soft terms in the observable sector.

  12. Dynamically sequestered F-term uplifting in extra dimension

    International Nuclear Information System (INIS)

    Abe, Hiroyuki; Higaki, Tetsutaro; Kobayashi, Tatsuo; Omura, Yuji

    2008-01-01

    We study moduli stabilization, the dynamical supersymmetry (SUSY) breaking, the uplifting of SUSY anti-de Sitter (AdS) vacuum and the sequestering of hidden sector in a five-dimensional supergravity model, where all modes of the visible sector and the hidden sector are originated from bulk fields. We clarify couplings between the visible and hidden sectors. The expressions for the visible sector soft SUSY breaking terms as well as the hidden sector potential are shown explicitly in our model. The sequestering is achieved dynamically by a wavefunction localization in extra dimension. We find that the tree-level soft scalar mass and the A-term can be suppressed at a SUSY breaking Minkowski minimum where the radius modulus is stabilized, while gaugino masses would be a mirage type

  13. Dynamic iterative beam hardening correction (DIBHC) in myocardial perfusion imaging using contrast-enhanced computed tomography.

    Science.gov (United States)

    Stenner, Philip; Schmidt, Bernhard; Allmendinger, Thomas; Flohr, Thomas; Kachelrie, Marc

    2010-06-01

    In cardiac perfusion examinations with computed tomography (CT) large concentrations of iodine in the ventricle and in the descending aorta cause beam hardening artifacts that can lead to incorrect perfusion parameters. The aim of this study is to reduce these artifacts by performing an iterative correction and by accounting for the 3 materials soft tissue, bone, and iodine. Beam hardening corrections are either implemented as simple precorrections which cannot account for higher order beam hardening effects, or as iterative approaches that are based on segmenting the original image into material distribution images. Conventional segmentation algorithms fail to clearly distinguish between iodine and bone. Our new algorithm, DIBHC, calculates the time-dependent iodine distribution by analyzing the voxel changes of a cardiac perfusion examination (typically N approximately 15 electrocardiogram-correlated scans distributed over a total scan time up to T approximately 30 s). These voxel dynamics are due to changes in contrast agent. This prior information allows to precisely distinguish between bone and iodine and is key to DIBHC where each iteration consists of a multimaterial (soft tissue, bone, iodine) polychromatic forward projection, a raw data comparison and a filtered backprojection. Simulations with a semi-anthropomorphic dynamic phantom and clinical scans using a dual source CT scanner with 2 x 128 slices, a tube voltage of 100 kV, a tube current of 180 mAs, and a rotation time of 0.28 seconds have been carried out. The uncorrected images suffer from beam hardening artifacts that appear as dark bands connecting large concentrations of iodine in the ventricle, aorta, and bony structures. The CT-values of the affected tissue are usually underestimated by roughly 20 HU although deviations of up to 61 HU have been observed. For a quantitative evaluation circular regions of interest have been analyzed. After application of DIBHC the mean values obtained deviate by

  14. Fault Detection and Correction for the Solar Dynamics Observatory Attitude Control System

    Science.gov (United States)

    Starin, Scott R.; Vess, Melissa F.; Kenney, Thomas M.; Maldonado, Manuel D.; Morgenstern, Wendy M.

    2007-01-01

    The Solar Dynamics Observatory is an Explorer-class mission that will launch in early 2009. The spacecraft will operate in a geosynchronous orbit, sending data 24 hours a day to a devoted ground station in White Sands, New Mexico. It will carry a suite of instruments designed to observe the Sun in multiple wavelengths at unprecedented resolution. The Atmospheric Imaging Assembly includes four telescopes with focal plane CCDs that can image the full solar disk in four different visible wavelengths. The Extreme-ultraviolet Variability Experiment will collect time-correlated data on the activity of the Sun's corona. The Helioseismic and Magnetic Imager will enable study of pressure waves moving through the body of the Sun. The attitude control system on Solar Dynamics Observatory is responsible for four main phases of activity. The physical safety of the spacecraft after separation must be guaranteed. Fine attitude determination and control must be sufficient for instrument calibration maneuvers. The mission science mode requires 2-arcsecond control according to error signals provided by guide telescopes on the Atmospheric Imaging Assembly, one of the three instruments to be carried. Lastly, accurate execution of linear and angular momentum changes to the spacecraft must be provided for momentum management and orbit maintenance. In thsp aper, single-fault tolerant fault detection and correction of the Solar Dynamics Observatory attitude control system is described. The attitude control hardware suite for the mission is catalogued, with special attention to redundancy at the hardware level. Four reaction wheels are used where any three are satisfactory. Four pairs of redundant thrusters are employed for orbit change maneuvers and momentum management. Three two-axis gyroscopes provide full redundancy for rate sensing. A digital Sun sensor and two autonomous star trackers provide two-out-of-three redundancy for fine attitude determination. The use of software to maximize

  15. Short-term mechanisms influencing volumetric brain dynamics

    Directory of Open Access Journals (Sweden)

    Nikki Dieleman

    2017-01-01

    Full Text Available With the use of magnetic resonance imaging (MRI and brain analysis tools, it has become possible to measure brain volume changes up to around 0.5%. Besides long-term brain changes caused by atrophy in aging or neurodegenerative disease, short-term mechanisms that influence brain volume may exist. When we focus on short-term changes of the brain, changes may be either physiological or pathological. As such determining the cause of volumetric dynamics of the brain is essential. Additionally for an accurate interpretation of longitudinal brain volume measures by means of neurodegeneration, knowledge about the short-term changes is needed. Therefore, in this review, we discuss the possible mechanisms influencing brain volumes on a short-term basis and set-out a framework of MRI techniques to be used for volumetric changes as well as the used analysis tools. 3D T1-weighted images are the images of choice when it comes to MRI of brain volume. These images are excellent to determine brain volume and can be used together with an analysis tool to determine the degree of volume change. Mechanisms that decrease global brain volume are: fluid restriction, evening MRI measurements, corticosteroids, antipsychotics and short-term effects of pathological processes like Alzheimer's disease, hypertension and Diabetes mellitus type II. Mechanisms increasing the brain volume include fluid intake, morning MRI measurements, surgical revascularization and probably medications like anti-inflammatory drugs and anti-hypertensive medication. Exercise was found to have no effect on brain volume on a short-term basis, which may imply that dehydration caused by exercise differs from dehydration by fluid restriction. In the upcoming years, attention should be directed towards studies investigating physiological short-term changes within the light of long-term pathological changes. Ultimately this may lead to a better understanding of the physiological short-term effects of

  16. An effective drift correction for dynamical downscaling of decadal global climate predictions

    Science.gov (United States)

    Paeth, Heiko; Li, Jingmin; Pollinger, Felix; Müller, Wolfgang A.; Pohlmann, Holger; Feldmann, Hendrik; Panitz, Hans-Jürgen

    2018-04-01

    Initialized decadal climate predictions with coupled climate models are often marked by substantial climate drifts that emanate from a mismatch between the climatology of the coupled model system and the data set used for initialization. While such drifts may be easily removed from the prediction system when analyzing individual variables, a major problem prevails for multivariate issues and, especially, when the output of the global prediction system shall be used for dynamical downscaling. In this study, we present a statistical approach to remove climate drifts in a multivariate context and demonstrate the effect of this drift correction on regional climate model simulations over the Euro-Atlantic sector. The statistical approach is based on an empirical orthogonal function (EOF) analysis adapted to a very large data matrix. The climate drift emerges as a dramatic cooling trend in North Atlantic sea surface temperatures (SSTs) and is captured by the leading EOF of the multivariate output from the global prediction system, accounting for 7.7% of total variability. The SST cooling pattern also imposes drifts in various atmospheric variables and levels. The removal of the first EOF effectuates the drift correction while retaining other components of intra-annual, inter-annual and decadal variability. In the regional climate model, the multivariate drift correction of the input data removes the cooling trends in most western European land regions and systematically reduces the discrepancy between the output of the regional climate model and observational data. In contrast, removing the drift only in the SST field from the global model has hardly any positive effect on the regional climate model.

  17. Position-Invariant Robust Features for Long-Term Recognition of Dynamic Outdoor Scenes

    Science.gov (United States)

    Kawewong, Aram; Tangruamsub, Sirinart; Hasegawa, Osamu

    A novel Position-Invariant Robust Feature, designated as PIRF, is presented to address the problem of highly dynamic scene recognition. The PIRF is obtained by identifying existing local features (i.e. SIFT) that have a wide baseline visibility within a place (one place contains more than one sequential images). These wide-baseline visible features are then represented as a single PIRF, which is computed as an average of all descriptors associated with the PIRF. Particularly, PIRFs are robust against highly dynamical changes in scene: a single PIRF can be matched correctly against many features from many dynamical images. This paper also describes an approach to using these features for scene recognition. Recognition proceeds by matching an individual PIRF to a set of features from test images, with subsequent majority voting to identify a place with the highest matched PIRF. The PIRF system is trained and tested on 2000+ outdoor omnidirectional images and on COLD datasets. Despite its simplicity, PIRF offers a markedly better rate of recognition for dynamic outdoor scenes (ca. 90%) than the use of other features. Additionally, a robot navigation system based on PIRF (PIRF-Nav) can outperform other incremental topological mapping methods in terms of time (70% less) and memory. The number of PIRFs can be reduced further to reduce the time while retaining high accuracy, which makes it suitable for long-term recognition and localization.

  18. Classifying genes to the correct Gene Ontology Slim term in Saccharomyces cerevisiae using neighbouring genes with classification learning

    Directory of Open Access Journals (Sweden)

    Tsatsoulis Costas

    2010-05-01

    Full Text Available Abstract Background There is increasing evidence that gene location and surrounding genes influence the functionality of genes in the eukaryotic genome. Knowing the Gene Ontology Slim terms associated with a gene gives us insight into a gene's functionality by informing us how its gene product behaves in a cellular context using three different ontologies: molecular function, biological process, and cellular component. In this study, we analyzed if we could classify a gene in Saccharomyces cerevisiae to its correct Gene Ontology Slim term using information about its location in the genome and information from its nearest-neighbouring genes using classification learning. Results We performed experiments to establish that the MultiBoostAB algorithm using the J48 classifier could correctly classify Gene Ontology Slim terms of a gene given information regarding the gene's location and information from its nearest-neighbouring genes for training. Different neighbourhood sizes were examined to determine how many nearest neighbours should be included around each gene to provide better classification rules. Our results show that by just incorporating neighbour information from each gene's two-nearest neighbours, the percentage of correctly classified genes to their correct Gene Ontology Slim term for each ontology reaches over 80% with high accuracy (reflected in F-measures over 0.80 of the classification rules produced. Conclusions We confirmed that in classifying genes to their correct Gene Ontology Slim term, the inclusion of neighbour information from those genes is beneficial. Knowing the location of a gene and the Gene Ontology Slim information from neighbouring genes gives us insight into that gene's functionality. This benefit is seen by just including information from a gene's two-nearest neighbouring genes.

  19. Crosstalk error correction through dynamical decoupling of single-qubit gates in capacitively coupled singlet-triplet semiconductor spin qubits

    Science.gov (United States)

    Buterakos, Donovan; Throckmorton, Robert E.; Das Sarma, S.

    2018-01-01

    In addition to magnetic field and electric charge noise adversely affecting spin-qubit operations, performing single-qubit gates on one of multiple coupled singlet-triplet qubits presents a new challenge: crosstalk, which is inevitable (and must be minimized) in any multiqubit quantum computing architecture. We develop a set of dynamically corrected pulse sequences that are designed to cancel the effects of both types of noise (i.e., field and charge) as well as crosstalk to leading order, and provide parameters for these corrected sequences for all 24 of the single-qubit Clifford gates. We then provide an estimate of the error as a function of the noise and capacitive coupling to compare the fidelity of our corrected gates to their uncorrected versions. Dynamical error correction protocols presented in this work are important for the next generation of singlet-triplet qubit devices where coupling among many qubits will become relevant.

  20. Can molecular dynamics simulations help in discriminating correct from erroneous protein 3D models?

    Directory of Open Access Journals (Sweden)

    Gibrat Jean-François

    2008-01-01

    Full Text Available Abstract Background Recent approaches for predicting the three-dimensional (3D structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potential functions and a reduced representation of the polypeptide chain. These simplifications facilitate the exploration of the protein conformational space but do not permit to capture entirely the subtle relationship that exists between the amino acid sequence and its native structure. It has been proposed that physics-based energy functions together with techniques for sampling the conformational space, e.g., Monte Carlo or molecular dynamics (MD simulations, are better suited to the task of modelling proteins at higher resolutions than those of models obtained with the former type of methods. In this study we monitor different protein structural properties along MD trajectories to discriminate correct from erroneous models. These models are based on the sequence-structure alignments provided by our fold recognition method, FROST. We define correct models as being built from alignments of sequences with structures similar to their native structures and erroneous models from alignments of sequences with structures unrelated to their native structures. Results For three test sequences whose native structures belong to the all-α, all-β and αβ classes we built a set of models intended to cover the whole spectrum: from a perfect model, i.e., the native structure, to a very poor model, i.e., a random alignment of the test sequence with a structure belonging to another structural class, including several intermediate models based on fold recognition alignments. We submitted these models to 11 ns of MD simulations at three different temperatures. We monitored along the corresponding trajectories the mean of the Root-Mean-Square deviations (RMSd with respect to the initial conformation, the RMSd fluctuations, the number of conformation clusters, the evolution of

  1. Development of a Regularized Dynamic System Response Curve for Real-Time Flood Forecasting Correction

    Directory of Open Access Journals (Sweden)

    Yiqun Sun

    2018-04-01

    Full Text Available The dynamic system response curve (DSRC is commonly applied as a real-time flood forecasting error correction method to improve the accuracy of real-time flood forecasting. It has been widely recognized that the least squares (OLS/LS method, employed by DSRC, breaks down ill-posed problems, and therefore, the DSRC method may lead to deterioration in performance caused by meaningless solutions. To address this problem, a diagnostically theoretical analysis was conducted to investigate the relationship between the numerical solution of the Fredholm equation of the first kind and the DSRC method. The analysis clearly demonstrates the derivation of the problem and has implications for an improved approach. To overcome the unstable problem, a new method using regularization techniques (Tikhonov regularization and L-Curve criterion is proposed. Moreover, in this study, to improve the performance of hydrological models, the new method is used as an error correction method to correct a variable from a hydrological model. The proposed method incorporates the information from a hydrological model structure. Based on the analysis of the hydrological model, the free water storage of the Xinanjiang rainfall-runoff (XAJ model is corrected to improve the model’s performance. A numerical example and a real case study are presented to compare the two methods. Results from the numerical example indicate that the mean Nash–Sutcliffe efficiency value (NSE of the regularized DSRC method (RDSRC decreased from 0.99 to 0.55, while the mean NSE of DSRC decreased from 0.98 to −1.84 when the noise level was increased. The overall performance measured by four different criteria clearly demonstrates the robustness of the RDSRC method. Similar results were obtained for the real case study. The mean NSE of 35 flood events obtained by RDSRC method was 0.92, which is significantly higher than the mean NSE of DSRC (0.7. The results demonstrate that the RDSRC method is much

  2. Study on the influence of stochastic properties of correction terms on the reliability of instantaneous network RTK

    Science.gov (United States)

    Próchniewicz, Dominik

    2014-03-01

    The reliability of precision GNSS positioning primarily depends on correct carrier-phase ambiguity resolution. An optimal estimation and correct validation of ambiguities necessitates a proper definition of mathematical positioning model. Of particular importance in the model definition is the taking into account of the atmospheric errors (ionospheric and tropospheric refraction) as well as orbital errors. The use of the network of reference stations in kinematic positioning, known as Network-based Real-Time Kinematic (Network RTK) solution, facilitates the modeling of such errors and their incorporation, in the form of correction terms, into the functional description of positioning model. Lowered accuracy of corrections, especially during atmospheric disturbances, results in the occurrence of unaccounted biases, the so-called residual errors. The taking into account of such errors in Network RTK positioning model is possible by incorporating the accuracy characteristics of the correction terms into the stochastic model of observations. In this paper we investigate the impact of the expansion of the stochastic model to include correction term variances on the reliability of the model solution. In particular the results of instantaneous solution that only utilizes a single epoch of GPS observations, is analyzed. Such a solution mode due to the low number of degrees of freedom is very sensitive to an inappropriate mathematical model definition. Thus the high level of the solution reliability is very difficult to achieve. Numerical tests performed for a test network located in mountain area during ionospheric disturbances allows to verify the described method for the poor measurement conditions. The results of the ambiguity resolution as well as the rover positioning accuracy shows that the proposed method of stochastic modeling can increase the reliability of instantaneous Network RTK performance.

  3. Von Bertalanffy's dynamics under a polynomial correction: Allee effect and big bang bifurcation

    Science.gov (United States)

    Leonel Rocha, J.; Taha, A. K.; Fournier-Prunaret, D.

    2016-02-01

    In this work we consider new one-dimensional populational discrete dynamical systems in which the growth of the population is described by a family of von Bertalanffy's functions, as a dynamical approach to von Bertalanffy's growth equation. The purpose of introducing Allee effect in those models is satisfied under a correction factor of polynomial type. We study classes of von Bertalanffy's functions with different types of Allee effect: strong and weak Allee's functions. Dependent on the variation of four parameters, von Bertalanffy's functions also includes another class of important functions: functions with no Allee effect. The complex bifurcation structures of these von Bertalanffy's functions is investigated in detail. We verified that this family of functions has particular bifurcation structures: the big bang bifurcation of the so-called “box-within-a-box” type. The big bang bifurcation is associated to the asymptotic weight or carrying capacity. This work is a contribution to the study of the big bang bifurcation analysis for continuous maps and their relationship with explosion birth and extinction phenomena.

  4. The dynamics of accounting terms in a globalized environment

    DEFF Research Database (Denmark)

    Fuertes-Olivera, Pedro A.; Nielsen, Sandro

    2014-01-01

    European accounting terminology is dynamic as term creation occurs on national, European Union and international levels. English is the lingua franca of accounting, which influences terminologies in other languages, usually through the work of translators, e.g. the translation of existing interna...... into Spanish; and the presence of novel metaphors in Spanish accounting. The data used in the discussion are taken from the accounting dictionaries, a collection of online dictionaries in three languages: Danish, English and Spanish.......European accounting terminology is dynamic as term creation occurs on national, European Union and international levels. English is the lingua franca of accounting, which influences terminologies in other languages, usually through the work of translators, e.g. the translation of existing...... international accounting standards. The combined influence of these forces is discussed in this chapter that explains the existence of a globalized trend towards a kind of cultural uniformity. This manifests itself in many ways, two of which are: the translation of English multiword accounting terms...

  5. Emulating short-term synaptic dynamics with memristive devices

    Science.gov (United States)

    Berdan, Radu; Vasilaki, Eleni; Khiat, Ali; Indiveri, Giacomo; Serb, Alexandru; Prodromakis, Themistoklis

    2016-01-01

    Neuromorphic architectures offer great promise for achieving computation capacities beyond conventional Von Neumann machines. The essential elements for achieving this vision are highly scalable synaptic mimics that do not undermine biological fidelity. Here we demonstrate that single solid-state TiO2 memristors can exhibit non-associative plasticity phenomena observed in biological synapses, supported by their metastable memory state transition properties. We show that, contrary to conventional uses of solid-state memory, the existence of rate-limiting volatility is a key feature for capturing short-term synaptic dynamics. We also show how the temporal dynamics of our prototypes can be exploited to implement spatio-temporal computation, demonstrating the memristors full potential for building biophysically realistic neural processing systems.

  6. Wormholes in higher dimensions with non-linear curvature terms from quantum gravity corrections

    Energy Technology Data Exchange (ETDEWEB)

    El-Nabulsi, Ahmad Rami [Neijiang Normal University, Neijiang, Sichuan (China)

    2011-11-15

    In this work, we discuss a 7-dimensional universe in the presence of a static traversable wormhole and a decaying cosmological constant and dominated by higher-order curvature effects expected from quantum gravity corrections. We confirmed the existence of wormhole solutions in the form of the Lovelock gravity. Many interesting and attractive features are discussed in some detail.

  7. Dynamical damping terms for symmetry-seeking shift conditions

    International Nuclear Information System (INIS)

    Alic, Daniela; Rezzolla, Luciano; Hinder, Ian; Moesta, Philipp

    2010-01-01

    Suitable gauge conditions are fundamental for stable and accurate numerical-relativity simulations of inspiralling compact binaries. A number of well-studied conditions have been developed over the last decade for both the lapse and the shift and these have been successfully used both in vacuum and non-vacuum spacetimes when simulating binaries with comparable masses. At the same time, recent evidence has emerged that the standard 'Gamma-driver' shift condition requires a careful and non-trivial tuning of its parameters to ensure long-term stable evolutions of unequal-mass binaries. We present a novel gauge condition in which the damping constant is promoted to be a dynamical variable and the solution of an evolution equation. We show that this choice removes the need for special tuning and provides a shift damping term which is free of instabilities in our simulations and dynamically adapts to the individual positions and masses of the binary black-hole system. Our gauge condition also reduces the variations in the coordinate size of the apparent horizon of the larger black hole and could therefore be useful when simulating binaries with very small mass ratios.

  8. CORRECTION OF FORECASTS OF INTERRELATED CURRENCY PAIRS IN TERMS OF SYSTEMS OF BALANCE RATIOS

    OpenAIRE

    Gertsekovich D. A.

    2015-01-01

    In this paper the problem of exchange rates forecast is logically considered a) traditionally as a task of forecast on the base of «stand-alone» equations of autoregression for each currency pair and b) as a result of forecast correction of autoregression equations system on the base of boundary conditions of balance ratios systems. As a criterion for quality of forecast constructed with empirical models we take the sum of deficiency quadrates of forecasts estimated for deductive currency pai...

  9. Medium-term dynamics of a middle Adriatic barred beach

    Directory of Open Access Journals (Sweden)

    M. Postacchini

    2017-09-01

    Full Text Available In recent years, attention has been paid to beach protection by means of soft and hard defenses. Along the Italian coast of the Adriatic Sea, sandy beaches are the most common landscape feature and around 70 % of the Marche region's coast (central Adriatic is protected by defense structures. The longest free-from-obstacle nearshore area in the region includes the beach of Senigallia, frequently monitored in the last decades and characterized by a multiple bar system, which represents a natural beach defense. The bathymetries surveyed in 2006, 2010, 2011, 2012 and 2013 show long-term stability, confirmed by a good adaptation of an analyzed stretch of the beach to the Dean-type equilibrium profile, though a strong short- to medium-term variability of the wave climate has been observed during the monitored periods. The medium-term dynamics of the beach, which deal with the evolution of submerged bars and are of the order of years or seasons, have been related to the wave climate collected, during the analyzed temporal windows, by a wave buoy located about 40 km off Senigallia. An overall interpretation of the hydrodynamics, sediment characteristics and seabed morphology suggests that the wave climate is fundamental for the morphodynamic changes of the beach in the medium term. These medium-term time ranges during which waves mainly come from NNE/ESE are characterized by a larger/smaller steepness and by a larger/smaller relative wave height, and seem to induce seaward/shoreward bar migration as well as bar smoothing/steepening. Moving southeastward, the bar dimension increases, while the equilibrium profile shape suggests the adaptation to a decreasing sediment size in the submerged beach. This is probably due to the presence of both the harbor jetty and river mouth north of the investigated area.

  10. Error correction in multi-fidelity molecular dynamics simulations using functional uncertainty quantification

    Energy Technology Data Exchange (ETDEWEB)

    Reeve, Samuel Temple; Strachan, Alejandro, E-mail: strachan@purdue.edu

    2017-04-01

    We use functional, Fréchet, derivatives to quantify how thermodynamic outputs of a molecular dynamics (MD) simulation depend on the potential used to compute atomic interactions. Our approach quantifies the sensitivity of the quantities of interest with respect to the input functions as opposed to its parameters as is done in typical uncertainty quantification methods. We show that the functional sensitivity of the average potential energy and pressure in isothermal, isochoric MD simulations using Lennard–Jones two-body interactions can be used to accurately predict those properties for other interatomic potentials (with different functional forms) without re-running the simulations. This is demonstrated under three different thermodynamic conditions, namely a crystal at room temperature, a liquid at ambient pressure, and a high pressure liquid. The method provides accurate predictions as long as the change in potential can be reasonably described to first order and does not significantly affect the region in phase space explored by the simulation. The functional uncertainty quantification approach can be used to estimate the uncertainties associated with constitutive models used in the simulation and to correct predictions if a more accurate representation becomes available.

  11. Stereoscopic 3D display with dynamic optical correction for recovering from asthenopia

    Science.gov (United States)

    Shibata, Takashi; Kawai, Takashi; Otsuki, Masaki; Miyake, Nobuyuki; Yoshihara, Yoshihiro; Iwasaki, Tsuneto

    2005-03-01

    The purpose of this study was to consider a practical application of a newly developed stereoscopic 3-D display that solves the problem of discrepancy between accommodation and convergence. The display uses dynamic optical correction to reduce the discrepancy, and can present images as if they are actually remote objects. The authors thought the display may assist in recovery from asthenopia, which is often caused when the eyes focus on a nearby object for a long time, such as in VDT (Visual Display Terminal) work. In general, recovery from asthenopia, and especially accommodative asthenopia, is achieved by focusing on distant objects. In order to verify this hypothesis, the authors performed visual acuity tests using Landolt rings before and after presenting stereoscopic 3-D images, and evaluated the degree of recovery from asthenopia. The experiment led to three main conclusions: (1) Visual acuity rose after viewing stereoscopic 3-D images on the developed display. (2) Recovery from asthenopia was particularly effective for the dominant eye in comparison with the other eye. (3) Interviews with the subjects indicated that the Landolt rings were particularly clear after viewing the stereoscopic 3-D images.

  12. Enabling full-field physics-based optical proximity correction via dynamic model generation

    Science.gov (United States)

    Lam, Michael; Clifford, Chris; Raghunathan, Ananthan; Fenger, Germain; Adam, Kostas

    2017-07-01

    As extreme ultraviolet lithography becomes closer to reality for high volume production, its peculiar modeling challenges related to both inter and intrafield effects have necessitated building an optical proximity correction (OPC) infrastructure that operates with field position dependency. Previous state-of-the-art approaches to modeling field dependency used piecewise constant models where static input models are assigned to specific x/y-positions within the field. OPC and simulation could assign the proper static model based on simulation-level placement. However, in the realm of 7 and 5 nm feature sizes, small discontinuities in OPC from piecewise constant model changes can cause unacceptable levels of edge placement errors. The introduction of dynamic model generation (DMG) can be shown to effectively avoid these dislocations by providing unique mask and optical models per simulation region, allowing a near continuum of models through the field. DMG allows unique models for electromagnetic field, apodization, aberrations, etc. to vary through the entire field and provides a capability to precisely and accurately model systematic field signatures.

  13. Unclassified Source Term and Radionuclide Data for Corrective Action Unit 98: Frenchman Flat Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    Farnham, Irene

    2005-09-01

    Frenchman Flat is one of several areas of the Nevada Test Site (NTS) used for underground nuclear testing (Figure 1-1). These nuclear tests resulted in groundwater contamination in the vicinity of the underground test areas. As a result, the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) is currently conducting a corrective action investigation (CAI) of the Frenchman Flat underground test areas. Since 1996, the Nevada Division of Environmental Protection (NDEP) has regulated NNSA/NSO corrective actions through the ''Federal Facility Agreement and Consent Order'' ([FFACO], 1996). Appendix VI of the FFACO agreement, ''Corrective Action Strategy'', was revised on December 7, 2000, and describes the processes that will be used to complete corrective actions, including those in the Underground Test Area (UGTA) Project. The individual locations covered by the agreement are known as corrective action sites (CASs), which are grouped into corrective action units (CAUs). The UGTA CASs are grouped geographically into five CAUs: Frenchman Flat, Central Pahute Mesa, Western Pahute Mesa, Yucca Flat/Climax Mine, and Rainier Mesa/Shoshone Mountain (Figure 1-1). These CAUs have distinctly different contaminant source, geologic, and hydrogeologic characteristics related to their location (FFACO, 1996). The Frenchman Flat CAU consists of 10 CASs located in the northern part of Area 5 and the southern part of Area 11 (Figure 1-1). This report documents the evaluation of the information and data available on the unclassified source term and radionuclide contamination for Frenchman Flat, CAU 98. The methodology used to estimate hydrologic source terms (HSTs) for the Frenchman Flat CAU is also documented. The HST of an underground nuclear test is the portion of the total inventory of radionuclides that is released over time into the groundwater following the test. The total residual inventory

  14. Unclassified Source Term and Radionuclide Data for Corrective Action Unit 98: Frenchman Flat Nevada Test Site, Nevada

    International Nuclear Information System (INIS)

    Farnham, Irene

    2005-01-01

    Frenchman Flat is one of several areas of the Nevada Test Site (NTS) used for underground nuclear testing (Figure 1-1). These nuclear tests resulted in groundwater contamination in the vicinity of the underground test areas. As a result, the U.S. Department of Energy (DOE), National Nuclear Security Administration Nevada Site Office (NNSA/NSO) is currently conducting a corrective action investigation (CAI) of the Frenchman Flat underground test areas. Since 1996, the Nevada Division of Environmental Protection (NDEP) has regulated NNSA/NSO corrective actions through the ''Federal Facility Agreement and Consent Order'' ([FFACO], 1996). Appendix VI of the FFACO agreement, ''Corrective Action Strategy'', was revised on December 7, 2000, and describes the processes that will be used to complete corrective actions, including those in the Underground Test Area (UGTA) Project. The individual locations covered by the agreement are known as corrective action sites (CASs), which are grouped into corrective action units (CAUs). The UGTA CASs are grouped geographically into five CAUs: Frenchman Flat, Central Pahute Mesa, Western Pahute Mesa, Yucca Flat/Climax Mine, and Rainier Mesa/Shoshone Mountain (Figure 1-1). These CAUs have distinctly different contaminant source, geologic, and hydrogeologic characteristics related to their location (FFACO, 1996). The Frenchman Flat CAU consists of 10 CASs located in the northern part of Area 5 and the southern part of Area 11 (Figure 1-1). This report documents the evaluation of the information and data available on the unclassified source term and radionuclide contamination for Frenchman Flat, CAU 98. The methodology used to estimate hydrologic source terms (HSTs) for the Frenchman Flat CAU is also documented. The HST of an underground nuclear test is the portion of the total inventory of radionuclides that is released over time into the groundwater following the test. The total residual inventory of radionuclides associated with one or

  15. Dynamics of heterogeneous oscillator ensembles in terms of collective variables

    Science.gov (United States)

    Pikovsky, Arkady; Rosenblum, Michael

    2011-04-01

    We consider general heterogeneous ensembles of phase oscillators, sine coupled to arbitrary external fields. Starting with the infinitely large ensembles, we extend the Watanabe-Strogatz theory, valid for identical oscillators, to cover the case of an arbitrary parameter distribution. The obtained equations yield the description of the ensemble dynamics in terms of collective variables and constants of motion. As a particular case of the general setup we consider hierarchically organized ensembles, consisting of a finite number of subpopulations, whereas the number of elements in a subpopulation can be both finite or infinite. Next, we link the Watanabe-Strogatz and Ott-Antonsen theories and demonstrate that the latter one corresponds to a particular choice of constants of motion. The approach is applied to the standard Kuramoto-Sakaguchi model, to its extension for the case of nonlinear coupling, and to the description of two interacting subpopulations, exhibiting a chimera state. With these examples we illustrate that, although the asymptotic dynamics can be found within the framework of the Ott-Antonsen theory, the transients depend on the constants of motion. The most dramatic effect is the dependence of the basins of attraction of different synchronous regimes on the initial configuration of phases.

  16. CORRECTION OF FORECASTS OF INTERRELATED CURRENCY PAIRS IN TERMS OF SYSTEMS OF BALANCE RATIOS

    Directory of Open Access Journals (Sweden)

    Gertsekovich D. A.

    2015-03-01

    Full Text Available In this paper the problem of exchange rates forecast is logically considered a traditionally as a task of forecast on the base of «stand-alone» equations of autoregression for each currency pair and b as a result of forecast correction of autoregression equations system on the base of boundary conditions of balance ratios systems. As a criterion for quality of forecast constructed with empirical models we take the sum of deficiency quadrates of forecasts estimated for deductive currency pairs. Practical approval confirmed that deductive models meet common requirements, provide accepted precision, show resistance to initial data and are free from series of deficiency of one index. However, extreme forecast errors tell that practical application of the approach offered needs further improvement.

  17. Complication Rates and Short-Term Outcomes After Operative Hammertoe Correction in Older Patients.

    Science.gov (United States)

    Mueller, Claire Mackenzie; Boden, Stephanie Ann; Boden, Allison Lee; Maidman, Samuel David; Cutler, Anya; Mignemi, Danielle; Bariteau, Jason

    2018-02-01

    Hammertoe deformities are the most common lesser toe deformity. To date, no studies have looked at outcomes of operative management in the geriatric population, which may be at greater risk for complications or functional compromise because of comorbidities. Data on 58 patients undergoing operative correction of hammertoe deformities were prospectively collected. Clinical outcomes were assessed using preoperative and postoperative visual analogue scale (VAS) and Short Form Health Survey (SF-36) scores with a minimum of 6-month follow-up. Patients were divided into 2 groups on the basis of age at the time of surgery: younger than 65 and 65 and older. Complication rates and mean VAS and SF-36 improvement were compared. Forty-seven patients met inclusion criteria (7 men, 40 women), with 26 patients (37 toes) in the younger cohort and 21 patients (39 toes) in the older cohort. Overall, patients demonstrated significant improvement from baseline to 6 and 12 months postoperatively in VAS ( P < .001 and P < .001) and SF-36 ( P < .001 and P < .001) scores. Mean improvement in VAS and SF-36 scores was not significantly different between the groups at 6 and 12 months postoperatively. Complications occurred in 13.5% and 10.3% of patients in the younger and older cohorts, respectively. Outcomes of operative correction of hammertoe deformities in older patients were similar to outcomes in younger patients after greater than 6 months of follow-up. Overall improvement in VAS and SF-36 was statistically significant for both cohorts. There was no associated increase in complications for older patients. Level, III comparative series.

  18. Complex dynamics in Josephson system with two external forcing terms

    International Nuclear Information System (INIS)

    Yang Jianping; Feng Wei; Jing Zhujun

    2006-01-01

    Josephson system with two external forcing terms is investigated. By applying Melnikov method, we prove that criterion of existence of chaos under periodic perturbation. By second-order averaging method and Melnikov method, we obtain the criterion of existence of chaos in averaged system under quasi-periodic perturbation for ω 2 =ω 1 +εν, and cannot prove the criterion of existence of chaos in averaged system under quasi-periodic perturbation for ω 2 =nω 1 +εν (n>=2 and n-bar N), where ν is not rational to ω 1 . We also study the effects of the parameters of system on dynamical behaviors by using numerical simulation. The numerical simulations, including bifurcation diagram of fixed points, bifurcation diagram of system in three- and two-dimensional space, homoclinic and heteroclinic bifurcation surface, Maximum Lyapunov exponent, phase portraits, Poincare map, are also plotted to illustrate theoretical analysis, and to expose the complex dynamical behaviors, including the period-n (n=1,2,5,7) orbits in different chaotic regions, cascades of period-doubling bifurcation from period-1, 2 and 5 orbits, reverse period-doubling bifurcation, onset of chaos which occurs more than once for two given external frequencies and chaos suddenly converting to periodic orbits, transient chaos with complex periodic windows and crisis, reverse period-5 bubble, non-attracting chaotic set and nice attracting chaotic set. In particular, we observe that the system can leave chaotic region to periodic motion by adjusting damping α, amplitude f 1 and frequency ω 2 of external forcing which can be considered as a control strategy

  19. Mid-term results of correction of Tetralogy of Fallot with absent pulmonary valve

    Directory of Open Access Journals (Sweden)

    Sachin Talwar

    2017-11-01

    Conclusions: In contrast to children and adults with TOF/APV, infants carry significant early mortality. But the mid-term outcome for patients who survive the initial repair of TOF/APV is acceptable. However, these patients require constant surveillance and irrespective of the methods of RVOT management, the reoperation rates are expected to be high as more of these patients survive into adulthood.

  20. Modelling the long-term vertical dynamics of salt marshes

    Science.gov (United States)

    Zoccarato, Claudia; Teatini, Pietro

    2017-04-01

    Salt marshes are vulnerable environments hosting complex interactions between physical and biological processes with a strong influence on the dynamics of the marsh evolution. The estimation and prediction of the elevation of a salt-marsh platform is crucial to forecast the marsh growth or regression under different scenarios considering, for example, the potential climate changes. The long-term vertical dynamics of a salt marsh is predicted with the aid of an original finite-element (FE) numerical model accounting for the marsh accretion and compaction and for the variation rates of the relative sea level rise, i.e., land subsidence of the marsh basement and eustatic rise of the sea level. The accretion term considers the vertical sedimentation of organic and inorganic material over the marsh surface, whereas the compaction reflects the progressive consolidation of the porous medium under the increasing load of the overlying younger deposits. The modelling approach is based on a 2D groundwater flow simulator, which provides the pressure evolution within a compacting/accreting vertical cross-section of the marsh assuming that the groundwater flow obeys the relative Darcy's law, coupled to a 1D vertical geomechanical module following Terzaghi's principle of effective intergranular stress. Soil porosity, permeability, and compressibility may vary with the effective intergranular stress according to empirically based relationships. The model also takes into account the geometric non-linearity arising from the consideration of large solid grain movements by using a Lagrangian approach with an adaptive FE mesh. The element geometry changes in time to follow the deposit consolidation and the element number increases in time to follow the sedimentation of new material. The numerical model is tested on different realistic configurations considering the influence of (i) the spatial distribution of the sedimentation rate in relation to the distance from the marsh margin, (ii

  1. Correcting for the free energy costs of bond or angle constraints in molecular dynamics simulations.

    Science.gov (United States)

    König, Gerhard; Brooks, Bernard R

    2015-05-01

    Free energy simulations are an important tool in the arsenal of computational biophysics, allowing the calculation of thermodynamic properties of binding or enzymatic reactions. This paper introduces methods to increase the accuracy and precision of free energy calculations by calculating the free energy costs of constraints during post-processing. The primary purpose of employing constraints for these free energy methods is to increase the phase space overlap between ensembles, which is required for accuracy and convergence. The free energy costs of applying or removing constraints are calculated as additional explicit steps in the free energy cycle. The new techniques focus on hard degrees of freedom and use both gradients and Hessian estimation. Enthalpy, vibrational entropy, and Jacobian free energy terms are considered. We demonstrate the utility of this method with simple classical systems involving harmonic and anharmonic oscillators, four-atomic benchmark systems, an alchemical mutation of ethane to methanol, and free energy simulations between alanine and serine. The errors for the analytical test cases are all below 0.0007kcal/mol, and the accuracy of the free energy results of ethane to methanol is improved from 0.15 to 0.04kcal/mol. For the alanine to serine case, the phase space overlaps of the unconstrained simulations range between 0.15 and 0.9%. The introduction of constraints increases the overlap up to 2.05%. On average, the overlap increases by 94% relative to the unconstrained value and precision is doubled. The approach reduces errors arising from constraints by about an order of magnitude. Free energy simulations benefit from the use of constraints through enhanced convergence and higher precision. The primary utility of this approach is to calculate free energies for systems with disparate energy surfaces and bonded terms, especially in multi-scale molecular mechanics/quantum mechanics simulations. This article is part of a Special Issue

  2. Improved UTE-based attenuation correction for cranial PET-MR using dynamic magnetic field monitoring

    International Nuclear Information System (INIS)

    Aitken, A. P.; Giese, D.; Tsoumpas, C.; Schleyer, P.; Kozerke, S.; Prieto, C.; Schaeffter, T.

    2014-01-01

    Purpose: Ultrashort echo time (UTE) MRI has been proposed as a way to produce segmented attenuation maps for PET, as it provides contrast between bone, air, and soft tissue. However, UTE sequences require samples to be acquired during rapidly changing gradient fields, which makes the resulting images prone to eddy current artifacts. In this work it is demonstrated that this can lead to misclassification of tissues in segmented attenuation maps (AC maps) and that these effects can be corrected for by measuring the true k-space trajectories using a magnetic field camera. Methods: The k-space trajectories during a dual echo UTE sequence were measured using a dynamic magnetic field camera. UTE images were reconstructed using nominal trajectories and again using the measured trajectories. A numerical phantom was used to demonstrate the effect of reconstructing with incorrect trajectories. Images of an ovine leg phantom were reconstructed and segmented and the resulting attenuation maps were compared to a segmented map derived from a CT scan of the same phantom, using the Dice similarity measure. The feasibility of the proposed method was demonstrated inin vivo cranial imaging in five healthy volunteers. Simulated PET data were generated for one volunteer to show the impact of misclassifications on the PET reconstruction. Results: Images of the numerical phantom exhibited blurring and edge artifacts on the bone–tissue and air–tissue interfaces when nominal k-space trajectories were used, leading to misclassification of soft tissue as bone and misclassification of bone as air. Images of the tissue phantom and thein vivo cranial images exhibited the same artifacts. The artifacts were greatly reduced when the measured trajectories were used. For the tissue phantom, the Dice coefficient for bone in MR relative to CT was 0.616 using the nominal trajectories and 0.814 using the measured trajectories. The Dice coefficients for soft tissue were 0.933 and 0.934 for the

  3. Long-term results of forearm lengthening and deformity correction by the Ilizarov method.

    Science.gov (United States)

    Orzechowski, Wiktor; Morasiewicz, Leszek; Krawczyk, Artur; Dragan, Szymon; Czapiński, Jacek

    2002-06-30

    Background. Shortening and deformity of the forearm is most frequently caused by congenital disorders or posttraumatic injury. Given its complex anatomy and biomechanics, the forearm is clearly the most difficult segment for lengthening and deformity correction. Material and methods. We analyzed 16 patients with shortening and deformity of the forearm, treated surgically, using the Ilizarov method in our Department from 1989 to 2001. in 9 cases 1-stage surgery was sufficient, while the remaining 7 patients underwent 2-5 stages of treatment. At total of 31 surgical operations were performed. The extent of forearm shortening ranged from 1,5 to 14,5 cm (5-70%). We development a new fixator based on Schanz half-pins. Results. The length of forearm lengthening per operative stage averaged 2,35 cm. the proportion of lengthening ranged from 6% to 48% with an average of 18,3%. The mean lengthening index was 48,15 days/cm. the per-patient rate of complications was 88% compared 45% per stage of treatment, mostly limited rotational mobility and abnormal consolidation of regenerated bone. Conclusions. Despite the high complication rate, the Ilizarov method is the method of choice for patients with forearm shortenings and deformities. Treatment is particularly indicated in patients with shortening caused by disproportionate length of the ulnar and forearm bones. Treatment should be managed so as cause the least possible damage to arm function, even at the cost of limited lengthening. Our new stabilizer based on Schanz half-pins makes it possible to preserve forearm rotation.

  4. Trans-sinusal maxillary distraction for correction of midfacial hypoplasia: long-term clinical results.

    Science.gov (United States)

    Nadjmi, N; Schutyser, F; Van Erum, R

    2006-10-01

    Maxillary distraction osteogenesis is indicated in severe angle class III malocclusions, and severe maxillary hypoplasia among some cleft patients and other craniofacial deformities. Twenty patients, aged 8-48 years (mean 17.8+/-10.5 SD) with maxillary and midfacial hypoplasia were treated. The follow-up period was 13-65 months (mean 35+/-16.3 SD). A trans-sinusal maxillary distractor was placed intraorally at each side of the maxilla. The distraction vector was predicted using specialist software, and was transferred to the patients using stereolithographic models and individual templates. A (high) Le Fort I type osteotomy was performed. The amount of activation varied from 8 to 17.5 mm (mean 13.1+/-2.9 SD). Soft and hard tissue formation resulted in complete healing across the distraction gaps. The distractors are almost completely submerged, and can be left in place as long as necessary to avoid relapse. Wit's appraisal was used to measure the stability of the long-term distraction results. Results up to 5 years after distraction showed considerable maxillary advancement with long-term stability. Ongoing growth of the facial skeleton must be considered when distraction osteogenesis is chosen in growing patients.

  5. A scatter-corrected list-mode reconstruction and a practical scatter/random approximation technique for dynamic PET imaging

    International Nuclear Information System (INIS)

    Cheng, J-C; Rahmim, Arman; Blinder, Stephan; Camborde, Marie-Laure; Raywood, Kelvin; Sossi, Vesna

    2007-01-01

    We describe an ordinary Poisson list-mode expectation maximization (OP-LMEM) algorithm with a sinogram-based scatter correction method based on the single scatter simulation (SSS) technique and a random correction method based on the variance-reduced delayed-coincidence technique. We also describe a practical approximate scatter and random-estimation approach for dynamic PET studies based on a time-averaged scatter and random estimate followed by scaling according to the global numbers of true coincidences and randoms for each temporal frame. The quantitative accuracy achieved using OP-LMEM was compared to that obtained using the histogram-mode 3D ordinary Poisson ordered subset expectation maximization (3D-OP) algorithm with similar scatter and random correction methods, and they showed excellent agreement. The accuracy of the approximated scatter and random estimates was tested by comparing time activity curves (TACs) as well as the spatial scatter distribution from dynamic non-human primate studies obtained from the conventional (frame-based) approach and those obtained from the approximate approach. An excellent agreement was found, and the time required for the calculation of scatter and random estimates in the dynamic studies became much less dependent on the number of frames (we achieved a nearly four times faster performance on the scatter and random estimates by applying the proposed method). The precision of the scatter fraction was also demonstrated for the conventional and the approximate approach using phantom studies

  6. Main corrective measures in an early phase of nuclear power plants’ preparation for safe long term operation

    Energy Technology Data Exchange (ETDEWEB)

    Krivanek, Robert, E-mail: r.krivanek@iaea.org [International Atomic Energy Agency (IAEA), Department of Nuclear Safety and Security, Operational Safety Section, Vienna 1400 (Austria); Fiedler, Jan, E-mail: fiedler@fme.vutbr.cz [University of Technology Brno, Faculty of Mechanical Engineering, Energy Institute, Technická 2896/2, 616 69 Brno (Czech Republic)

    2017-05-15

    Highlights: • Results of SALTO missions provide the most important issues for safe long term operation (LTO) of nuclear power plants. • The most important technical corrective measures in an early phase of preparation for safe LTO are described. • Their satisfactory resolution creates a basis for further activities to demonstrate preparedness for safe LTO. - Abstract: This paper presents the analysis of main technical deficiencies of nuclear power plants (NPPs) in preparedness for safe long term operation (LTO) and the main corrective measures in an early phase of preparation for safe LTO of NPPs. It focuses on technical aspects connected with management of physical ageing of NPP structures, systems and components (SSCs). It uses as a basis results of IAEA SALTO missions performed between 2005 and 2016 (see also paper NED8805 in Nuclear Engineering and Design in May 2016) and the personal experiences of the authors with preparation of NPPs for safe LTO. This paper does not discuss other important aspects of safe LTO of NPPs, e.g. national nuclear energy policies, compliance of NPPs with the latest international requirements on design, obsolescence, environmental impact and economic aspects of LTO. Chapter 1 provides a brief introduction of the current status of the NPP’ fleet in connection with LTO. Chapter 2 provides an overview of SALTO peer review service results with a focus on deficiencies related to physical ageing of safety SSCs and a demonstration that SSCs will perform their safety function during the intended period of LTO. Chapter 3 discusses the main corrective measures which NPPs typically face during the preparation for demonstration of safe LTO. Chapter 4 summarizes the current status of the NPP’ fleet in connection with LTO and outlines further steps needed in preparation for safe LTO.

  7. Relativistic corrections to the static energy in terms of Wilson loops at weak coupling

    Energy Technology Data Exchange (ETDEWEB)

    Peset, Clara [Technische Universitaet Muenchen, Physik Department T31, Garching (Germany); Pineda, Antonio [Universitat Autonoma de Barcelona, Grup de Fisica Teorica, Dept. Fisica y IFAE-BIST, Barcelona (Spain); Stahlhofen, Maximilian [Johannes Gutenberg University, PRISMA Cluster of Excellence, Institute of Physics, Mainz (Germany)

    2017-10-15

    We consider the O(1/m) and the spin-independent momentum-dependent O(1/m{sup 2}) quasi-static energies of heavy quarkonium (with unequal masses). They are defined nonperturbatively in terms of Wilson loops. We determine their short-distance behavior through O(α{sup 3}) and O(α{sup 2}), respectively. In particular, we calculate the ultrasoft contributions to the quasi-static energies, which requires the resummation of potential interactions. Our results can be directly compared to lattice simulations. In addition, we also compare the available lattice data with the expectations from effective string models for the long-distance behavior of the quasi-static energies. (orig.)

  8. Long-term results after atrial correction of complete transposition of the great arteries.

    Science.gov (United States)

    Merlo, M; de Tommasi, S M; Brunelli, F; Abbruzzese, P A; Crupi, G; Ghidoni, I; Casari, A; Pitì, A; Mamprin, F; Parenzan, L

    1991-02-01

    This study presents the late results for the first 104 consecutive patients surviving and atrial repair for transposition of the great arteries (TGA) between January 1971 and December 1978 (group 1). Mean follow-up was 12 years (range, 0.1 to 17.7 years). The actuarial survival rate at 18 years was 84.2% (70% confidence limits, 79% to 88%) for simple TGA and 93.7% (70% confidence limits, 84% to 97%) for complex TGA. Nine of the 11 deaths were sudden. Two (2.6%) of the 78 late survivors operated on for simple TGA are in New York Heart Association functional class III or IV versus 4 (26.7%) of the 15 survivors with complex TGA; the other patients are doing very well. To better assess long-term results, we report the findings for randomly obtained electrocardiograms, Holter monitor recordings, radionuclide angiographic studies, and cardiac catheterizations performed in 1987 in a larger group of 159 long-term survivors of atrial repair operated on at Ospedale Riuniti di Bergamo from January 1971 to December 1984 (group 2), which includes all of group 1. The findings confirm that the arterial switch repair is the procedure of choice for complex TGA and that there is a major incidence (approximately 10%) of systemic right ventricular dysfunction and rhythm disturbances after the atrial repair. On the other hand, our late survival rate at 18 years of 84% for simple TGA with 97.5% of the patients in functional class I is a result that should be kept in mind, especially in institutions where the arterial switch is a relatively new approach and presumably is a higher risk to cause early death.

  9. Study on fitness functions of genetic algorithm for dynamically correcting nuclide atmospheric diffusion model

    International Nuclear Information System (INIS)

    Ji Zhilong; Ma Yuanwei; Wang Dezhong

    2014-01-01

    Background: In radioactive nuclides atmospheric diffusion models, the empirical dispersion coefficients were deduced under certain experiment conditions, whose difference with nuclear accident conditions is a source of deviation. A better estimation of the radioactive nuclide's actual dispersion process could be done by correcting dispersion coefficients with observation data, and Genetic Algorithm (GA) is an appropriate method for this correction procedure. Purpose: This study is to analyze the fitness functions' influence on the correction procedure and the forecast ability of diffusion model. Methods: GA, coupled with Lagrange dispersion model, was used in a numerical simulation to compare 4 fitness functions' impact on the correction result. Results: In the numerical simulation, the fitness function with observation deviation taken into consideration stands out when significant deviation exists in the observed data. After performing the correction procedure on the Kincaid experiment data, a significant boost was observed in the diffusion model's forecast ability. Conclusion: As the result shows, in order to improve dispersion models' forecast ability using GA, observation data should be given different weight in the fitness function corresponding to their error. (authors)

  10. Measurement correction method for force sensor used in dynamic pressure calibration based on artificial neural network optimized by genetic algorithm

    Science.gov (United States)

    Gu, Tingwei; Kong, Deren; Shang, Fei; Chen, Jing

    2017-12-01

    We present an optimization algorithm to obtain low-uncertainty dynamic pressure measurements from a force-transducer-based device. In this paper, the advantages and disadvantages of the methods that are commonly used to measure the propellant powder gas pressure, the applicable scope of dynamic pressure calibration devices, and the shortcomings of the traditional comparison calibration method based on the drop-weight device are firstly analysed in detail. Then, a dynamic calibration method for measuring pressure using a force sensor based on a drop-weight device is introduced. This method can effectively save time when many pressure sensors are calibrated simultaneously and extend the life of expensive reference sensors. However, the force sensor is installed between the drop-weight and the hammerhead by transition pieces through the connection mode of bolt fastening, which causes adverse effects such as additional pretightening and inertia forces. To solve these effects, the influence mechanisms of the pretightening force, the inertia force and other influence factors on the force measurement are theoretically analysed. Then a measurement correction method for the force measurement is proposed based on an artificial neural network optimized by a genetic algorithm. The training and testing data sets are obtained from calibration tests, and the selection criteria for the key parameters of the correction model is discussed. The evaluation results for the test data show that the correction model can effectively improve the force measurement accuracy of the force sensor. Compared with the traditional high-accuracy comparison calibration method, the percentage difference of the impact-force-based measurement is less than 0.6% and the relative uncertainty of the corrected force value is 1.95%, which can meet the requirements of engineering applications.

  11. Long-term Correction in Sleep Disturbance Is Sustained After Arthroscopic Rotator Cuff Repair.

    Science.gov (United States)

    Horneff, John G; Tjoumakaris, Fotios; Wowkanech, Charles; Pepe, Matthew; Tucker, Bradford; Austin, Luke

    2017-06-01

    Sleep disturbance is a major complaint of patients with rotator cuff disease that often leads them to seek treatment. The authors previously reported a prospective analysis of patients who underwent rotator cuff repair and found that sleep disturbance significantly improved at 3 months after surgery. That improvement in sleep was maintained at 6 months. In the current study, the authors sought to gain medium-term data on this same population at greater than 2 years. The hypotheses were that improvement in sleep disturbance after arthroscopic rotator cuff repair is maintained at 2-year follow-up and that the continued use of narcotic pain medication has a negative effect on sleep quality at 2-year follow-up. Case series; Level of evidence, 4. The original cohort of patients was contacted at a minimum of 24 months after their surgery. Thirty-seven of the 56 patients (66%) involved in the original study were available. Patient outcomes were scored using the Pittsburgh Sleep Quality Index (PSQI), Simple Shoulder Test (SST), visual analog scale (VAS) for pain, and Single Assessment Numeric Evaluation (SANE). The newly obtained scores were compared with prior scores, which ranged from preoperatively to 6 months postoperatively. The statistically significant improvement of the PSQI score demonstrated in our prior analysis at 6 months postoperatively was maintained, with a mean PSQI score of 5.5 for the 37 patients followed beyond 24 months. Of those patients, 41% still had a PSQI score >5, indicative of sleep disturbance. However, even those patients in our study with a PSQI score >5, indicative of sleep disturbance, had an improved mean score of 9.3 at greater than 24 months compared with those patients with a PSQI score >5 at 6 months, who had a mean PSQI score of 11.5 ( P = .13). Both the SST and VAS scores displayed continued improvement at greater than 24 months, with both displaying moderate strength correlation to the PSQI score (VAS: Spearman rho = 0.479, P < .001

  12. Bias Correction in the Dynamic Panel Data Model with a Nonscalar Disturbance Covariance Matrix

    NARCIS (Netherlands)

    Bun, M.J.G.

    2003-01-01

    Approximation formulae are developed for the bias of ordinary and generalized Least Squares Dummy Variable (LSDV) estimators in dynamic panel data models. Results from Kiviet [Kiviet, J. F. (1995), on bias, inconsistency, and efficiency of various estimators in dynamic panel data models, J.

  13. Multi-atlas attenuation correction supports full quantification of static and dynamic brain PET data in PET-MR

    Science.gov (United States)

    Mérida, Inés; Reilhac, Anthonin; Redouté, Jérôme; Heckemann, Rolf A.; Costes, Nicolas; Hammers, Alexander

    2017-04-01

    In simultaneous PET-MR, attenuation maps are not directly available. Essential for absolute radioactivity quantification, they need to be derived from MR or PET data to correct for gamma photon attenuation by the imaged object. We evaluate a multi-atlas attenuation correction method for brain imaging (MaxProb) on static [18F]FDG PET and, for the first time, on dynamic PET, using the serotoninergic tracer [18F]MPPF. A database of 40 MR/CT image pairs (atlases) was used. The MaxProb method synthesises subject-specific pseudo-CTs by registering each atlas to the target subject space. Atlas CT intensities are then fused via label propagation and majority voting. Here, we compared these pseudo-CTs with the real CTs in a leave-one-out design, contrasting the MaxProb approach with a simplified single-atlas method (SingleAtlas). We evaluated the impact of pseudo-CT accuracy on reconstructed PET images, compared to PET data reconstructed with real CT, at the regional and voxel levels for the following: radioactivity images; time-activity curves; and kinetic parameters (non-displaceable binding potential, BPND). On static [18F]FDG, the mean bias for MaxProb ranged between 0 and 1% for 73 out of 84 regions assessed, and exceptionally peaked at 2.5% for only one region. Statistical parametric map analysis of MaxProb-corrected PET data showed significant differences in less than 0.02% of the brain volume, whereas SingleAtlas-corrected data showed significant differences in 20% of the brain volume. On dynamic [18F]MPPF, most regional errors on BPND ranged from -1 to  +3% (maximum bias 5%) for the MaxProb method. With SingleAtlas, errors were larger and had higher variability in most regions. PET quantification bias increased over the duration of the dynamic scan for SingleAtlas, but not for MaxProb. We show that this effect is due to the interaction of the spatial tracer-distribution heterogeneity variation over time with the degree of accuracy of the attenuation maps. This

  14. An Improved Dynamical Downscaling Method with GCM Bias Corrections and Its Validation with 30 Years of Climate Simulations

    KAUST Repository

    Xu, Zhongfeng

    2012-09-01

    An improved dynamical downscaling method (IDD) with general circulation model (GCM) bias corrections is developed and assessed over North America. A set of regional climate simulations is performed with the Weather Research and Forecasting Model (WRF) version 3.3 embedded in the National Center for Atmospheric Research\\'s (NCAR\\'s) Community Atmosphere Model (CAM). The GCM climatological means and the amplitudes of interannual variations are adjusted based on the National Centers for Environmental Prediction (NCEP)-NCAR global reanalysis products (NNRP) before using them to drive WRF. In this study, the WRF downscaling experiments are identical except the initial and lateral boundary conditions derived from the NNRP, original GCM output, and bias-corrected GCM output, respectively. The analysis finds that the IDD greatly improves the downscaled climate in both climatological means and extreme events relative to the traditional dynamical downscaling approach (TDD). The errors of downscaled climatological mean air temperature, geopotential height, wind vector, moisture, and precipitation are greatly reduced when the GCM bias corrections are applied. In the meantime, IDD also improves the downscaled extreme events characterized by the reduced errors in 2-yr return levels of surface air temperature and precipitation. In comparison with TDD, IDD is also able to produce a more realistic probability distribution in summer daily maximum temperature over the central U.S.-Canada region as well as in summer and winter daily precipitation over the middle and eastern United States. © 2012 American Meteorological Society.

  15. On one-loop corrections to matching conditions of lattice HQET including 1/m{sub b} terms

    Energy Technology Data Exchange (ETDEWEB)

    Korcyl, Piotr [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC

    2013-12-15

    HQET is an effective theory for QCD with N{sub f} light quarks and a massive valence quark if the mass of the latter is much bigger than LQCD. As any effective theory, HQET is predictive only when a set of parameters has been determined through a process called matching. The non-perturbative matching procedure including 1/m{sub b} terms, developed by the ALPHA collaboration, consists of 19 carefully chosen observables which are precisely computable in lattice QCD as well as in lattice HQET. The matching conditions are then a set of 19 equations which relate the QCD and HQET values of these observables. We present a study of one-loop corrections to two generic matching observables involving correlation function with an insertion of the A{sub 0} operator. Our results enable us to quantify the quality of the relevant observables in view of the envisaged nonperturbative implementation of this matching procedure.

  16. Nutritional and Hormonal Status of Premature Infants Born with Intrauterine Growth Restriction at the Term Corrected Age.

    Science.gov (United States)

    Belyaeva, I A; Namazova-Baranova, L S; Bombardirova, E P; Okuneva, M V

    Inadequate nutrition supply during the period of intrauterine growth and the first year of life leads to persistent metabolic changes and provokes development of various diseases. Тo compare physical development, body composition, and hormonal status (insulin, insulin-like growth factor-1 (IGF-1), somatotropic hormone (STH), C-Peptide, cortisol) indices in premature infants born with intrauterine growth restriction (IUGR) at the term corrected age with the same indices in mature infants with IUGR and premature infants with weight appropriate for their gestational age (GA). А crossover study of anthropometric measures, body composition and growth hormones changes assessment was carried out. It included 140 premature infants with weight appropriate for their GA, 58 premature infants with IUGR and 64 mature infants with IUGR. Anthropometric measures were assessed with Fenton and Anthro growth charts (WHO, 2009); body composition was studied with the air plethysmography method (РЕA POD, LMi, USA). Level of hormones in blood serum was assessed with biochemical methods. It is found that anthropometric measures in premature infants with weight appropriate for their GA and premature infants with IUGR at the term corrected age did not have any significant differences while premature infants with IUGR tended to have lower weight. Studying body composition we found that both groups of premature infants had slightly higher level of fat mass in comparison with mature infants. High concentration of insulin, cortisol, IGF-1, and C-peptide was found in premature and mature infants with IUGR. Instead, lower levels of STH was found in infants with IUGR. Formula fed premature infants (comparing to breastfed ones) had higher levels of fat mass, insulin, IGF-1, and C-peptide. Mature infants with IUGR did not tend to have the correlation between levels of fat mass, insulin, IGF-1, C-peptide, and type of feeding. Not only insufficient intrauterine growth but also nutrition pattern

  17. Implementing a generic method for bias correction in statistical models using random effects, with spatial and population dynamics examples

    DEFF Research Database (Denmark)

    Thorson, James T.; Kristensen, Kasper

    2016-01-01

    Statistical models play an important role in fisheries science when reconciling ecological theory with available data for wild populations or experimental studies. Ecological models increasingly include both fixed and random effects, and are often estimated using maximum likelihood techniques...... configurations of an age-structured population dynamics model. This simulation experiment shows that the epsilon-method and the existing bias-correction method perform equally well in data-rich contexts, but the epsilon-method is slightly less biased in data-poor contexts. We then apply the epsilon......-method to a spatial regression model when estimating an index of population abundance, and compare results with an alternative bias-correction algorithm that involves Markov-chain Monte Carlo sampling. This example shows that the epsilon-method leads to a biologically significant difference in estimates of average...

  18. Uncertainty of long-term CO2 flux estimates due to the choice of the spectral correction method

    Science.gov (United States)

    Ibrom, Andreas; Geißler, Simon; Pilegaard, Kim

    2010-05-01

    The eddy covariance system at the Danish beech forest long-term flux observation site at Sorø has been intensively examined. Here we investigate which systematic and non-systematic effects the choice of the spectral correction method has on long-term net CO2 flux estimates and their components. Ibrom et al. (2007) gave an overview over different ways to correct for low-pass filtering of the atmospheric turbulent signal by a closed path eddy covariance system. They used degraded temperature time series for spectral correction of low-pass filtered signals. In this new study, correction for high-pass filtering was also included, which made it anyway necessary to use model co-spectra. We compared different ways of adapting different kinds of model co-spectra to the wealth of 14 years high frequency raw data. As the trees grew, the distance between the sonic anemometer and the displacement height decreased over time. The study enabled us to compare the two approaches and different variants of them to give recommendations on their use. The analysis showed that model spectra should not be derived from co-spectra between the vertical wind speed (w) and the scalars measured with the closed path system, i.e. CO2 and H20 concentrations, but instead with sonic temperature (T) w cospectra, to avoid low-pass filtering effects on the estimation of the co-spectral peak frequency (fx). This concern was already expressed earlier in the above mentioned study, but here we show the quantitative effects. The wT co-spectra did not show any height effect on fx as it was suggested in generally used parameterizations. A possible reason for this difference is that measurements, like in all forest flux sites, took place in the roughness sub-layer and not in the inertial sub-layer. At the same time the shape of the relationship between fx and the stability parameter ? differed much from that of often used parameterizations (e.g. from Horst, 1997). The shift of fx towards higher frequencies at

  19. Surviving in Changing Seascapes: Sediment Dynamics as Bottleneck for Long-Term Seagrass Presence

    NARCIS (Netherlands)

    Suykerbuyk, W.; Bouma, T.J.; Govers, L.L.; Giesen, K.; de Jong, D.J.; Herman, P.M.J.; Hendriks, J.; van Katwijk, M.M.

    2016-01-01

    Changes in the seascape often result in altered hydrodynamics that lead to coinciding changes in sediment dynamics. Little is known on how altered sediment dynamics affect long-term seagrass persistence. We studied the thresholds of sediment dynamics in relation to seagrass presence by comparing

  20. Optimization of nonimaging focusing heliostat in dynamic correction of astigmatism for a wide range of incident angles.

    Science.gov (United States)

    Chong, Kok-Keong

    2010-05-15

    To overcome astigmatism has always been a great challenge in designing a heliostat capable of focusing the sunlight on a small receiver throughout the year. In this Letter, a nonimaging focusing heliostat with a dynamic adjustment of facet mirrors in a group manner has been analyzed for optimizing the astigmatic correction in a wide range of incident angles. This what is to the author's knowledge a new heliostat is not only designed to serve the purpose of concentrating sunlight to several hundreds of suns, but also to significantly reduce the variation of the solar flux distribution with the incident angle.

  1. Short-term mechanisms influencing volumetric brain dynamics

    NARCIS (Netherlands)

    Dieleman, Nikki; Koek, Huiberdina L.; Hendrikse, Jeroen

    2017-01-01

    With the use of magnetic resonance imaging (MRI) and brain analysis tools, it has become possible to measure brain volume changes up to around 0.5%. Besides long-term brain changes caused by atrophy in aging or neurodegenerative disease, short-term mechanisms that influence brain volume may exist.

  2. The importance of correct specification of tribological parameters in dynamical systems modelling

    Science.gov (United States)

    Alaci, S.; Ciornei, F. C.; Romanu, I. C.; Ciornei, M. C.

    2018-01-01

    When modelling the behaviour of dynamical systems, the friction phenomenon cannot be neglected. Dry and fluid friction may occur, but dry friction has more severe effects upon the behaviour of the systems, based on the fact that the introduced discontinuities are more important. In the modelling of dynamical systems, dry friction is the main cause of occurrence of the bifurcation phenomenon. These aspects become more complex if, in the case of dry friction, static and dynamic frictions are put forward. The behaviour of a simple dynamical system is studied, consisting in a prismatic body linked to the ground by a spring, placed on a conveyor belt. The theoretical model is described by a nonlinear differential equation which after numerical integration leads to the conclusion that the steady motion of the prism is an un-damped oscillatory motion. The system was qualitatively modelled using specialised software for dynamical analysis. It was impractical to obtain a steady uniform translational motion of a rigid, therefore the conveyor belt was replaced by a metallic disc in uniform rotation motion. The attempts to compare the CAD model to the theoretical model were unsuccessful because the efforts of selecting the tribological parameters directed to the conclusion that the motion of the prism is a damped oscillation. To decide which of the methods depicts reality, a test-rig was assembled and it indicated a sustained oscillation. The conclusion is that the model employed by the dynamical analysis software cannot describe the actual model and a more complex model is required in the description of the friction phenomenon.

  3. Analysis of positron annihilation lifetime data by numerical Laplace inversion: Corrections for source terms and zero-time shift errors

    International Nuclear Information System (INIS)

    Gregory, R.B.

    1991-01-01

    We have recently described modifications to the program CONTIN for the solution of Fredholm integral equations with convoluted kernels of the type that occur in the analysis of positron annihilation lifetime data. In this article, modifications to the program to correct for source terms in the sample and reference decay curves and for shifts in the position of the zero-time channel of the sample and reference data are described. Unwanted source components, expressed as a discrete sum of exponentials, may be removed from both the sample and reference data by modification of the sample data alone, without the need for direct knowledge of the instrument resolution function. Shifts in the position of the zero-time channel of up to half the channel width of the multichannel analyzer can be corrected. Analyses of computer-simulated test data indicate that the quality of the reconstructed annihilation rate probability density functions is improved by employing a refernce material with a short lifetime and indicate that reference materials which generate free positrons by quenching positronium formation (i.e. strong oxidizing agents) have lifetimes that are too long (400-450 ps) to provide reliable estimates of the lifetime parameters for the shortlived components with the methods described here. Well-annealed single crystals of metals with lifetimes less than 200 ps, such as molybdenum (123 ps) and aluminium (166 ps) do not introduce significant errors in estimates of the lifetime parameters and are to be preferred as reference materials. The performance of our modified version of CONTIN is illustrated by application to positron annihilation in polytetrafluoroethylene. (orig.)

  4. Modeling Long-Term Fluvial Incision : Shall we Care for the Details of Short-Term Fluvial Dynamics?

    Science.gov (United States)

    Lague, D.; Davy, P.

    2008-12-01

    Fluvial incision laws used in numerical models of coupled climate, erosion and tectonics systems are mainly based on the family of stream power laws for which the rate of local erosion E is a power function of the topographic slope S and the local mean discharge Q : E = K Qm Sn. The exponents m and n are generally taken as (0.35, 0.7) or (0.5, 1), and K is chosen such that the predicted topographic elevation given the prevailing rates of precipitation and tectonics stay within realistic values. The resulting topographies are reasonably realistic, and the coupled system dynamics behaves somehow as expected : more precipitation induces increased erosion and localization of the deformation. Yet, if we now focus on smaller scale fluvial dynamics (the reach scale), recent advances have suggested that discharge variability, channel width dynamics or sediment flux effects may play a significant role in controlling incision rates. These are not factored in the simple stream power law model. In this work, we study how these short- term details propagate into long-term incision dynamics within the framework of surface/tectonics coupled numerical models. To upscale the short term dynamics to geological timescales, we use a numerical model of a trapezoidal river in which vertical and lateral incision processes are computed from fluid shear stress at a daily timescale, sediment transport and protection effects are factored in, as well as a variable discharge. We show that the stream power law model might still be a valid model but that as soon as realistic effects are included such as a threshold for sediment transport, variable discharge and dynamic width the resulting exponents m and n can be as high as 2 and 4. This high non-linearity has a profound consequence on the sensitivity of fluvial relief to incision rate. We also show that additional complexity does not systematically translates into more non-linear behaviour. For instance, considering only a dynamical width

  5. Multi-exposure high dynamic range image synthesis with camera shake correction

    Science.gov (United States)

    Li, Xudong; Chen, Yongfu; Jiang, Hongzhi; Zhao, Huijie

    2017-10-01

    Machine vision plays an important part in industrial online inspection. Owing to the nonuniform illuminance conditions and variable working distances, the captured image tends to be over-exposed or under-exposed. As a result, when processing the image such as crack inspection, the algorithm complexity and computing time increase. Multiexposure high dynamic range (HDR) image synthesis is used to improve the quality of the captured image, whose dynamic range is limited. Inevitably, camera shake will result in ghost effect, which blurs the synthesis image to some extent. However, existed exposure fusion algorithms assume that the input images are either perfectly aligned or captured in the same scene. These assumptions limit the application. At present, widely used registration based on Scale Invariant Feature Transform (SIFT) is usually time consuming. In order to rapidly obtain a high quality HDR image without ghost effect, we come up with an efficient Low Dynamic Range (LDR) images capturing approach and propose a registration method based on ORiented Brief (ORB) and histogram equalization which can eliminate the illumination differences between the LDR images. The fusion is performed after alignment. The experiment results demonstrate that the proposed method is robust to illumination changes and local geometric distortion. Comparing with other exposure fusion methods, our method is more efficient and can produce HDR images without ghost effect by registering and fusing four multi-exposure images.

  6. Short-term memory in olfactory network dynamics

    OpenAIRE

    Stopfer, Mark; Laurent, Gilles

    1999-01-01

    Neural assemblies in a number of animal species display self-organized, synchronized oscillations in response to sensory stimuli in a variety of brain areas. In the olfactory system of insects, odour-evoked oscillatory synchronization of antennal lobe projection neurons (PNs) is superimposed on slower and stimulus-specific temporal activity patterns. Hence, each odour activates a specific and dynamic projection neuron assembly whose evolution during a stimulus is locked to the oscillation clo...

  7. Short-term memory in olfactory network dynamics

    Science.gov (United States)

    Stopfer, Mark; Laurent, Gilles

    1999-12-01

    Neural assemblies in a number of animal species display self-organized, synchronized oscillations in response to sensory stimuli in a variety of brain areas.. In the olfactory system of insects, odour-evoked oscillatory synchronization of antennal lobe projection neurons (PNs) is superimposed on slower and stimulus-specific temporal activity patterns. Hence, each odour activates a specific and dynamic projection neuron assembly whose evolution during a stimulus is locked to the oscillation clock. Here we examine, using locusts, the changes in population dynamics of projection-neuron assemblies over repeated odour stimulations, as would occur when an animal first encounters and then repeatedly samples an odour for identification or localization. We find that the responses of these assemblies rapidly decrease in intensity, while they show a marked increase in spike time precision and inter-neuronal oscillatory coherence. Once established, this enhanced precision in the representation endures for several minutes. This change is stimulus-specific, and depends on events within the antennal lobe circuits, independent of olfactory receptor adaptation: it may thus constitute a form of sensory memory. Our results suggest that this progressive change in olfactory network dynamics serves to converge, over repeated odour samplings, on a more precise and readily classifiable odour representation, using relational information contained across neural assemblies.

  8. Long-term 4D Geoelectrical Imaging of Moisture Dynamics in an Active Landslide

    Science.gov (United States)

    Uhlemann, S.; Chambers, J. E.; Wilkinson, P. B.; Maurer, H.; Meldrum, P.; Gunn, D.; Smith, A.; Dijkstra, T.

    2016-12-01

    Landslides are a major natural hazard, endangering communities and infrastructure worldwide. Mitigating landslide risk relies on understanding causes and triggering processes, which are often linked to moisture dynamics in slopes causing material softening and elevated pore water pressures. Geoelectrical monitoring is frequently applied to study landslide hydrology. However, its sensitivity to sensor movements has been a challenge for long-term studies on actively failing slopes. Although 2D data acquisition has previously been favoured, it provides limited resolution and relatively poor representation of important 3D landslide structures. We present a novel methodology to incorporate electrode movements into a time-lapse 3D inversion workflow, resulting in a virtually artefact-free time-series of resistivity models. Using temperature correction and laboratory hydro-geophysical relationships, resistivity models are translated into models of moisture content. The data span more than three years, enabling imaging of processes pre- and post landslide reactivation. In the two years before reactivation, the models showed surficial wetting and drying, drainage pathways, and deeper groundwater dynamics. During reactivation, exceptionally high moisture contents were imaged throughout the slope, which was confirmed by independent measurements. Preferential flow was imaged that stabilized parts of the landslide by diverting moisture, and thus dissipating pore pressures, from the slip surface. The results highlight that moisture levels obtained from resistivity monitoring may provide a better activity threshold than rainfall intensity. Based on this work, pro-active remediation measures could be designed and effective early-warning systems implemented. Eventually, resistivity monitoring that can account for moving electrodes may provide a new means for pro-active mitigation of landslide risk, especially for communities and critical infrastructure.

  9. Dynamical Response of Catalytic Systems in a CS Corrected Environmental Transmission Electron Microscope

    DEFF Research Database (Denmark)

    Hansen, Thomas Willum; Dunin-Borkowski, Rafal E.; Boothroyd, Chris

    2010-01-01

    . In a catalytic reactor, the particles tend to sinter under reaction conditions resulting in the formation of larger particles and a loss of catalytic activity. Several models of sintering in different systems have been put forward [4,5]. However, most investigations have been post mortem studies, revealing only...... energies and energy barriers for sintering processes can be studied. The surface structures of catalytic materials are highly dependent on the surrounding atmosphere. The combined capabilities of ETEM and image CS correction provide unique possibilities to study this relationship. However, in order...... as function of Ar pressure in the pole piece gap. References [1] I. Chorkendorff and J.W. Niemantsverdriet, Concepts of Modern Catalysis and Kinetics, Wiley-VCH, Weinheim, 2003. [2] www.nacatsoc.org [3] A.K. Datye, J. Catal. 216 (2003) 144. [4] J.T. Richardson and J.G. Crump, J. Catal. 56 (1979) 417. [5] C. H...

  10. Dynamics of Supported Metal Nanoparticles Observed in a CS Corrected Environmental Transmission Electron Microscope

    DEFF Research Database (Denmark)

    Hansen, Thomas Willum; Dunin-Borkowski, Rafal E.; Wagner, Jakob Birkedal

    resulting in the formation of larger particles and a loss of catalytic performance. Several models of sintering in different systems have been put forward [1,2]. However, most investigations have been post mortem studies, revealing only the final state of the catalyst. Transmission electron microscopy (TEM....... The combined capabilities of ETEM and image CS correction provide unique possibilities to study this relationship. However, in order to fully quantify image contrast from such experiments, a deeper understanding of the scattering of fast electrons in the presence of gas molecules in the pole piece gap...... of the microscope is needed. As industrial catalysts are usually complex high surface area materials, they are often not suited for fundamental studies. For this purpose, model systems consisting of gold nanoparticles on sheets of low surface area boron nitride and graphite supports were produced. Sheets...

  11. Correction of the kinetic blur and representation of heart dynamics in nuclear imagery

    International Nuclear Information System (INIS)

    Ignaszewski, A.; Vaillant, D.; Sabatier, J.P.; Fernandez, Y.

    1975-01-01

    In heart cavity studies the simplicity and harmlessness nuclear imagery are great advantages, but it is necessary to improve on the data obtainable by this technique. The usual image is faulty, owing to the presence of a kinetic softness, and deficient because it fails to account for the mobility of the walls. An attempt was made to correct the kinetic softness on an image and to reconstitute the film of a heart cycle, an aim achieved by combining a computer with the camera. The examination conditions generally adopted include storage of all data and a reconstitution of the entire cycle is programmed taking a multiple time unit of 20ms; this supplies a sequence of images which when observed in succession resembles the heat contractility film [fr

  12. Long-Term Monitoring of Water Dynamics in the Sahel Region Using the Multi-Sar

    Science.gov (United States)

    Bertram, A.; Wendleder, A.; Schmitt, A.; Huber, M.

    2016-06-01

    Fresh water is a scarce resource in the West-African Sahel region, seasonally influenced by droughts and floods. Particularly in terms of climate change, the importance of wetlands increases for flora, fauna, human population, agriculture, livestock and fishery. Hence, access to open water is a key factor. Long-term monitoring of water dynamics is of great importance, especially with regard to the spatio-temporal extend of wetlands and drylands. It can predict future trends and facilitate the development of adequate management strategies. Lake Tabalak, a Ramsar wetland of international importance, is one of the most significant ponds in Niger and a refuge for waterbirds. Nevertheless, human population growth increased the pressure on this ecosystem, which is now degrading for all uses. The main objective of the study is a long-term monitoring of the Lake Tabalak's water dynamics to delineate permanent and seasonal water bodies, using weather- and daytime-independent multi-sensor and multi-temporal Synthetic Aperture Radar (SAR) data available for the study area. Data of the following sensors from 1993 until 2016 are used: Sentinel-1A, TerraSARX, ALOS PALSAR-1/2, Envisat ASAR, RADARSAT-1/2, and ERS-1/2. All SAR data are processed with the Multi-SAR-System, unifying the different characteristics of all above mentioned sensors in terms of geometric, radiometric and polarimetric resolution to a consistent format. The polarimetric representation in Kennaugh elements allows fusing single-polarized data acquired by older sensors with multi-polarized data acquired by current sensors. The TANH-normalization guarantees a consistent and therefore comparable description in a closed data range in terms of radiometry. The geometric aspect is solved by projecting all images to an earth-fixed coordinate system correcting the brightness by the help of the incidence angle. The elevation model used in the geocoding step is the novel global model produced by the TanDEM-X satellite

  13. An Artificial Neural Network Based Short-term Dynamic Prediction of Algae Bloom

    Directory of Open Access Journals (Sweden)

    Yao Junyang

    2014-06-01

    Full Text Available This paper proposes a method of short-term prediction of algae bloom based on artificial neural network. Firstly, principal component analysis is applied to water environmental factors in algae bloom raceway ponds to get main factors that influence the formation of algae blooms. Then, a model of short-term dynamic prediction based on neural network is built with the current chlorophyll_a values as input and the chlorophyll_a values in the next moment as output to realize short-term dynamic prediction of algae bloom. Simulation results show that the model can realize short-term prediction of algae bloom effectively.

  14. A system dynamics analysis of energy consumption and corrective policies in Iranian iron and steel industry

    International Nuclear Information System (INIS)

    Ansari, Nastaran; Seifi, Abbas

    2012-01-01

    Iron and steel industry is the most energy intensive industrial sector in Iran. Long time subsidized energy has led to low energy efficiency in this industry. The sudden subsidy reform of energy prices in Iran is expected to have a great impact on steel production and energy consumption. A system dynamics model is presented in this paper to analyze steel demand, production and energy consumption in an integrated framework. A co-flow structure is used to show how subsidy reform affects energy consumption in the long run. The main focus of this paper is on direct and indirect natural gas consumption in the steel industry. Scrap based Electric Arc Furnace technology has been evaluated as an energy efficient way for steel making. The energy consumption in steel industry is estimated under various steel production and export scenarios while taking into account new energy prices to see the outlook of possible energy demand in steel industry over next 20 years. For example it is shown that under reference production scenario, potential reduction in gas consumption forced by complete removal of energy subsidy and utilizing scrap could lead to 85 billion cubic meters of gas saving over the next 20 years. -- Highlights: ► We develop a system dynamics model to analyze steel demand, production and energy consumption in Iran. ► Various scenarios have been simulated to see the energy demand of Iranian steel industry over the next 20 years. ► A co-flow structure is used to show how subsidy reform would affect energy consumption in the long run. ► A co-flow structure has been built into the SD model to formulate consumers' behavior in response to energy prices. ► Scrap based Electric Arc Furnace technology has been evaluated as an energy efficient alternative for steel making.

  15. Magnetospheric storm dynamics in terms of energy output rate

    International Nuclear Information System (INIS)

    Prigancova, A.; Feldstein, Ya.I.

    1992-01-01

    Using hourly values of both the global magnetospheric disturbance characteristic DR, and AE index of auroral ionospheric currents during magnetic storm intervals, the energy output rate dynamics is evaluated for a magnetic storm main/recovery phase and a whole storm interval. The magnetospheric response to the solar wind energy input rate under varying interplanetary and magnetospheric conditions is considered from the temporal variability point of view. The peculiarities of the response are traced separately. As far as quantitative characteristics of energy output rate are concerned, the time dependence pattern of the ring current decay parameter is emphasized to be fairly important. It is pointed out that more insight into the plasma processes, especially at L = 3 - 5, is needed for adequate evidence of the dependence. (Author)

  16. Bodily tides near the 1:1 spin-orbit resonance: correction to Goldreich's dynamical model

    Science.gov (United States)

    Williams, James G.; Efroimsky, Michael

    2012-12-01

    Spin-orbit coupling is often described in an approach known as " the MacDonald torque", which has long become the textbook standard due to its apparent simplicity. Within this method, a concise expression for the additional tidal potential, derived by MacDonald (Rev Geophys 2:467-541, 1994), is combined with a convenient assumption that the quality factor Q is frequency-independent (or, equivalently, that the geometric lag angle is constant in time). This makes the treatment unphysical because MacDonald's derivation of the said formula was, very implicitly, based on keeping the time lag frequency-independent, which is equivalent to setting Q scale as the inverse tidal frequency. This contradiction requires the entire MacDonald treatment of both non-resonant and resonant rotation to be rewritten. The non-resonant case was reconsidered by Efroimsky and Williams (Cel Mech Dyn Astron 104:257-289, 2009), in application to spin modes distant from the major commensurabilities. In the current paper, we continue this work by introducing the necessary alterations into the MacDonald-torque-based model of falling into a 1-to-1 resonance. (The original version of this model was offered by Goldreich (Astron J 71:1-7, 1996). Although the MacDonald torque, both in its original formulation and in its corrected version, is incompatible with realistic rheologies of minerals and mantles, it remains a useful toy model, which enables one to obtain, in some situations, qualitatively meaningful results without resorting to the more rigorous (and complicated) theory of Darwin and Kaula. We first address this simplified model in application to an oblate primary body, with tides raised on it by an orbiting zero-inclination secondary. (Here the role of the tidally-perturbed primary can be played by a satellite, the perturbing secondary being its host planet. A planet may as well be the perturbed primary, its host star acting as the tide-raising secondary). We then extend the model to a

  17. Predicting long-term and short-term tidal flat morphodynamics using a dynamic equilibrium theory

    NARCIS (Netherlands)

    Hu, Z.; Wang, Z.B.; Zitman, T.J.; Stive, M.J.F.; Bouma, T.J.

    2015-01-01

    Dynamic equilibrium theory is a fruitful concept, which we use to systematically explain the tidal flat morphodynamic response to tidal currents, wind waves, sediment supply, and other sedimentological drivers. This theory stems from a simple analytical model that derives the tide- or wave-dominated

  18. The dynamic effect of exchange-rate volatility on Turkish exports: Parsimonious error-correction model approach

    Directory of Open Access Journals (Sweden)

    Demirhan Erdal

    2015-01-01

    Full Text Available This paper aims to investigate the effect of exchange-rate stability on real export volume in Turkey, using monthly data for the period February 2001 to January 2010. The Johansen multivariate cointegration method and the parsimonious error-correction model are applied to determine long-run and short-run relationships between real export volume and its determinants. In this study, the conditional variance of the GARCH (1, 1 model is taken as a proxy for exchange-rate stability, and generalized impulse-response functions and variance-decomposition analyses are applied to analyze the dynamic effects of variables on real export volume. The empirical findings suggest that exchangerate stability has a significant positive effect on real export volume, both in the short and the long run.

  19. Correction of dynamic multipoles for APPLE-II undulator with flat wires

    International Nuclear Information System (INIS)

    Kikuchi, Y.; Hosaka, M.; Takashima, Y.; Yamamoto, N.; Adachi, M.; Zen, H.; Katoh, M.

    2010-01-01

    APPLE-II undulator can produce quasi-monochromatic light of different polarization though it is a relatively simple magnetic circuit. Therefore, it has been installed in many synchrotron radiation facilities and will be installed in Central Japan Synchrotron Radiation Research Facility under construction in Aichi prefecture. APPLE-II undulator also has been installed in UVSOR facility. When the undulator is operated in vertical polarization mode with narrower gap of 40 mm, the lifetime of electron beam through the storage ring significantly decreases.The reason is considered as dynamic multipole kicks in the undulator, which strongly depends on the undulator gap. Multi-wires, which are installed in the upper surface and the under surface of undulator beam duct, are candidate to compensate the multipole effects, because the multi-wires can generate arbitrary magnetic fields. This paper reports the result of numerical investigation on multipoles in the undulator by a three-dimensional magnetostatics computer code RADIA, the orbital calculation based on the numerical analysis and the preliminary experiment with flat wires. (author)

  20. Dynamic multi-coil tailored excitation for transmit B1 correction at 7 Tesla.

    Science.gov (United States)

    Umesh Rudrapatna, S; Juchem, Christoph; Nixon, Terence W; de Graaf, Robin A

    2016-07-01

    Tailored excitation (TEx) based on interspersing multiple radio frequency pulses with linear gradient and higher-order shim pulses can be used to obtain uniform flip angle in the presence of large radio frequency transmission (B 1+) inhomogeneity. Here, an implementation of dynamic, multislice tailored excitation using the recently developed multi-coil nonlinear shim hardware (MC-DTEx) is reported. MC-DTEx was developed and tested both in a phantom and in vivo at 7 T, and its efficacy was quantitatively assessed. Predicted outcomes of MC-DTEx and DTEx based on spherical harmonic shims (SH-DTEx) were also compared. For a planned 30 ° flip angle, in a phantom, the standard deviation in excitation improved from 28% (regular excitation) to 12% with MC-DTEx. The SD in in vivo excitation improved from 22 to 12%. The improvements achieved with experimental MC-DTEx closely matched the theoretical predictions. Simulations further showed that MC-DTEx outperforms SH-DTEx for both scenarios. Successful implementation of multislice MC-DTEx is presented and is shown to be capable of homogenizing excitation over more than twofold B 1+ variations. Its benefits over SH-DTEx are also demonstrated. A distinct advantage of MC hardware over SH shim hardware is the absence of significant eddy current effects, which allows for a straightforward, multislice implementation of MC-DTEx. Magn Reson Med 76:83-93, 2016. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

  1. Estimation of the Rotational Terms of the Dynamic Response Matrix

    Directory of Open Access Journals (Sweden)

    D. Montalvão

    2004-01-01

    Full Text Available The dynamic response of a structure can be described by both its translational and rotational receptances. The latter ones are frequently not considered because of the difficulties in applying a pure moment excitation or in measuring rotations. However, in general, this implies a reduction up to 75% of the complete model. On the other hand, if a modification includes a rotational inertia, the rotational receptances of the unmodified system are needed. In one method, more commonly found in the literature, a so called T-block is attached to the structure. Then, a force, applied to an arm of the T-block, generates a moment together with a force at the connection point. The T-block also allows for angular displacement measurements. Nevertheless, the results are often not quite satisfactory. In this work, an alternative method based upon coupling techniques is developed, in which rotational receptances are estimated without the need of applying a moment excitation. This is accomplished by introducing a rotational inertia modification when rotating the T-block. The force is then applied in its centroid. Several numerical and experimental examples are discussed so that the methodology can be clearly described. The advantages and limitations are identified within the practical application of the method.

  2. Long-term mercury dynamics in UK soils

    International Nuclear Information System (INIS)

    Tipping, E.; Wadsworth, R.A.; Norris, D.A.; Hall, J.R.; Ilyin, I.

    2011-01-01

    A model assuming first-order losses by evasion and leaching was used to evaluate Hg dynamics in UK soils since 1850. Temporal deposition patterns of Hg were constructed from literature information. Inverse modelling indicated that 30% of 898 rural sites receive Hg only from the global circulation, while in 51% of cases local deposition exceeds global. Average estimated deposition is 16 μg Hg m -2 a -1 to rural soils, 19 μg Hg m -2 a -1 to rural and non-rural soils combined. UK soils currently hold 2490 tonnes of reactive Hg, of which 2140 tonnes are due to anthropogenic deposition, mostly local in origin. Topsoil currently releases 5.1 tonnes of Hg 0 per annum to the atmosphere, about 50% more than the anthropogenic flux. Sorptive retention of Hg in the lower soil exerts a strong control on surface water Hg concentrations. Following decreases in inputs, soil Hg concentrations are predicted to decline over hundreds of years. - Highlights: → Spatial data for mercury in UK soils can be related to past atmospheric deposition. → The residence time of Hg (c. 400 years) depends on gaseous evasion and leaching. → UK soils currently contribute more Hg 0 to the atmosphere than human activities. → Sorption of Hg by deeper soil is a strong control on surface water concentrations. - Atmospherically-deposited anthropogenic mercury, mostly of local origin, has accumulated in UK soils, and is now a significant source of Hg 0 to the global circulation.

  3. Effect of Nondissipative Terms in Dynamical Phases of Vortex Matter in a Periodic Pinning Array

    Science.gov (United States)

    Arovas, Daniel

    2000-03-01

    The zero temperature dynamical phases of driven vortex lattices [1] are reconsidered, introducing a nondynamical term (proportional to the sine of the Hall angle) into the equations of motion. While such a term does not affect the static thermodynamic phases of the system, it may have a profound effect on the dynamics. We find that finite Hall angle tends to reduce the effect of pinning in certain dynamical phases. [1] C. Reichhardt, C. J. Olson, and F. Nori, Phys. Rev. B 58, 6534, 1998.

  4. Long term follow up after surgery in congenitally corrected transposition of the great arteries with a right ventricle in the systemic circulation

    NARCIS (Netherlands)

    A.J.J.C. Bogers (Ad); S.J. Head (Stuart); P.L. de Jong (Peter); M. Witsenburg (Maarten); A.P. Kappetein (Arie Pieter)

    2010-01-01

    textabstractAim of the study: To investigate the long-term outcome of surgical treatment for congenitally corrected transposition of the great arteries (CCTGA), in patients with biventricular repair with the right ventricle as systemic ventricle.Methods: A total of 32 patients with CCTGA were

  5. Long-term mercury dynamics in UK soils

    Energy Technology Data Exchange (ETDEWEB)

    Tipping, E., E-mail: et@ceh.ac.uk [Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP (United Kingdom); Wadsworth, R.A. [Centre for Ecology and Hydrology, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP (United Kingdom); Norris, D.A.; Hall, J.R. [Centre for Ecology and Hydrology, Environment Centre Wales, Deiniol Road, Bangor, Gwynedd LL57 2UW (United Kingdom); Ilyin, I. [Meteorological Synthesizing Centre - East, Krasina pereulok, 16/1, 123056 Moscow (Russian Federation)

    2011-12-15

    A model assuming first-order losses by evasion and leaching was used to evaluate Hg dynamics in UK soils since 1850. Temporal deposition patterns of Hg were constructed from literature information. Inverse modelling indicated that 30% of 898 rural sites receive Hg only from the global circulation, while in 51% of cases local deposition exceeds global. Average estimated deposition is 16 {mu}g Hg m{sup -2} a{sup -1} to rural soils, 19 {mu}g Hg m{sup -2} a{sup -1} to rural and non-rural soils combined. UK soils currently hold 2490 tonnes of reactive Hg, of which 2140 tonnes are due to anthropogenic deposition, mostly local in origin. Topsoil currently releases 5.1 tonnes of Hg{sup 0} per annum to the atmosphere, about 50% more than the anthropogenic flux. Sorptive retention of Hg in the lower soil exerts a strong control on surface water Hg concentrations. Following decreases in inputs, soil Hg concentrations are predicted to decline over hundreds of years. - Highlights: > Spatial data for mercury in UK soils can be related to past atmospheric deposition. > The residence time of Hg (c. 400 years) depends on gaseous evasion and leaching. > UK soils currently contribute more Hg{sup 0} to the atmosphere than human activities. > Sorption of Hg by deeper soil is a strong control on surface water concentrations. - Atmospherically-deposited anthropogenic mercury, mostly of local origin, has accumulated in UK soils, and is now a significant source of Hg{sup 0} to the global circulation.

  6. Correction for photobleaching in dynamic fluorescence microscopy: application in the assessment of pharmacokinetic parameters in ultrasound-mediated drug delivery

    International Nuclear Information System (INIS)

    Derieppe, M; Bos, C; De Greef, M; Moonen, C; Denis de Senneville, B

    2016-01-01

    We have previously demonstrated the feasibility of monitoring ultrasound-mediated uptake of a hydrophilic model drug in real time with dynamic confocal fluorescence microscopy. In this study, we evaluate and correct the impact of photobleaching to improve the accuracy of pharmacokinetic parameter estimates. To model photobleaching of the fluorescent model drug SYTOX Green, a photobleaching process was added to the current two-compartment model describing cell uptake. After collection of the uptake profile, a second acquisition was performed when SYTOX Green was equilibrated, to evaluate the photobleaching rate experimentally. Photobleaching rates up to 5.0 10 −3 s −1 were measured when applying power densities up to 0.2 W.cm −2 . By applying the three-compartment model, the model drug uptake rate of 6.0 10 −3 s −1 was measured independent of the applied laser power. The impact of photobleaching on uptake rate estimates measured by dynamic fluorescence microscopy was evaluated. Subsequent compensation improved the accuracy of pharmacokinetic parameter estimates in the cell population subjected to sonopermeabilization. (paper)

  7. Long-term dynamics of the hemiparasite Rhinanthus angustifolius and its relationship with vegetation structure

    NARCIS (Netherlands)

    Ameloot, Els; Verheyen, Kris; Bakker, Jan P.; De Vries, Yzaak; Hermy, Martin

    2006-01-01

    Questions: 1. How are the long-term dynamics of the root hemiparasite Rhinanthus angustifolius related to vegetation structure, grassland management and climate? 2. Does R. angustifolius have a long-term impact on standing crop and community composition? Location: A formerly fertilized grassland,

  8. Long-term Associations of an Early Corrected Ventricular Septal Defect and Stress Systems of Child and Mother at Primary School Age.

    Science.gov (United States)

    Stonawski, Valeska; Vollmer, Laura; Köhler-Jonas, Nicola; Rohleder, Nicolas; Golub, Yulia; Purbojo, Ariawan; Moll, Gunther H; Heinrich, Hartmut; Cesnjevar, Robert A; Kratz, Oliver; Eichler, Anna

    2017-01-01

    Ventricular septal defect (VSD) is the most common congenital heart defect, with larger VSDs typically being corrected with an open-heart surgery during infancy. Long-term consequences of a VSD-corrective surgery on stress systems of child and mother are still unknown. The aim of the present study is to investigate the associations of an early corrected VSD and diurnal cortisol release of child and mother. 26 children (12 boys) between 6 and 9 years old, who underwent surgery for an isolated VSD within the first 3 years of life, and their mothers participated in the study. Their diurnal cortisol profiles were compared to a sex-, age-, and socioeconomic status-matched healthy control group. Within the VSD group, associations between cortisol and characteristics of surgery and hospitalization were investigated. Child and mother psychopathological symptoms were considered as a possible interfering mechanism of altered cortisol profiles. Diurnal cortisol profiles of children with an early corrected VSD did not differ from those of controls. However, mothers of affected children exhibited higher cortisol levels in the morning ( p  early corrected VSD, in terms of comparable diurnal cortisol profiles with healthy controls, according to a comparable mother-rated psychopathology. Mothers of affected children reveal altered diurnal cortisol levels, without differences in self-rated psychopathology. This divergence should be clarified in future research.

  9. Comparative study of short-term cardiovascular autonomic control in cardiac surgery patients who underwent coronary artery bypass grafting or correction of valvular heart disease.

    Science.gov (United States)

    Shvartz, Vladimir A; Kiselev, Anton R; Karavaev, Anatoly S; Vulf, Kristina A; Borovkova, Ekaterina I; Prokhorov, Mikhail D; Petrosyan, Andrey D; Bockeria, Olga L

    2018-01-01

    Introduction: Our aim was to perform a comparative study of short-term cardiovascular autonomic control in cardiac surgery patients who underwent coronary artery bypass grafting (CABG) or surgical correction of valvular heart disease (SCVHD ). Methods: The synchronous 15 minutes records of heart rate variability (HRV) and finger's photoplethysmographic waveform variability (PPGV) were performed in 42 cardiac surgery patients (12 women) aged 61.8 ± 8.6 years (mean ± standard deviation), who underwent CABG, and 36 patients (16 women) aged 54.2 ± 14.9 years, who underwent SCVHD , before surgery and in 5-7 days after surgery. Conventional time and frequency domain measures of HRV and index S of synchronization between the slow oscillations in PPGV and HRV were analyzed. We also calculated personal dynamics of these indices after surgery. Results: We found no differences ( Р > 0.05) in all studied autonomic indices (preoperative and post-surgery) between studied patients' groups, except for the preoperative heart rate, which was higher in patients who underwent SCVHD ( P = 0.013). We have shown a pronounced preoperative and post-surgery variability (magnitude of inter-quartile ranges) of all autonomic indices in studied patients. In the cluster analysis based on cardiovascular autonomic indices (preoperative and post-surgery), we divided all patients into two clusters (38 and 40 subjects) which did not differ in all clinical characteristics (except for the preoperative hematocrit, P = 0.038), index S, and all post-surgery HRV indices. First cluster (38 patients) had higher preoperative values of the HR, TP, HF, and HF%, and lower preoperative values of the LF% and LF/HF. Conclusion: The variability of cardiovascular autonomic indices in on-pump cardiac surgery patients (two characteristic clusters were identified based on preoperative indices) was not associated with their clinical characteristics and features of surgical procedure (including cardioplegia).

  10. Exploiting short-term memory in soft body dynamics as a computational resource.

    Science.gov (United States)

    Nakajima, K; Li, T; Hauser, H; Pfeifer, R

    2014-11-06

    Soft materials are not only highly deformable, but they also possess rich and diverse body dynamics. Soft body dynamics exhibit a variety of properties, including nonlinearity, elasticity and potentially infinitely many degrees of freedom. Here, we demonstrate that such soft body dynamics can be employed to conduct certain types of computation. Using body dynamics generated from a soft silicone arm, we show that they can be exploited to emulate functions that require memory and to embed robust closed-loop control into the arm. Our results suggest that soft body dynamics have a short-term memory and can serve as a computational resource. This finding paves the way towards exploiting passive body dynamics for control of a large class of underactuated systems. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  11. Pedagogical terms of correction of motive sphere of persons of ripe years with the purchased blindness by facilities of playing activity

    Directory of Open Access Journals (Sweden)

    Kemkina V.I.

    2011-12-01

    Full Text Available The problem of correction of motive sphere of adults blind facilities of playing activity is considered. The pedagogical terms of correction of motive sphere of adults with the purchased blindness are considered. In experiment took part blind adults at the age 22-35 years. It is set that correction-developing teaching the motive actions of blind adults must be concertedly with the level of their development and the differentiated individual approach is foreseen. It is recommended to be oriented on the level of general development of these people, exposure of their potential and actual motive possibilities. It is well-proven that systematic application of facilities of motive activity is provided by the valuable mastering of vitally important motions, development of motive capabilities and capacity for an orientation in space.

  12. DYNAMICS OF THE ANXIETY DISORDERS IN THE COURSE OF SHORT-TERM PSYCHOTHERAPY

    Directory of Open Access Journals (Sweden)

    T.N. Hmylova

    2008-06-01

    Full Text Available The tendency of psychotherapy modern concepts referring to the short-term forms having been taken into account, we carried out the research aimed at the study of short-term form personality-oriented psychotherapy effect on the anxiety disorder dynamics. 103 patients with neurotic disorders were examined in the neurosis and psychotherapy department of the Bekhterev Psychoneurological Research Institute. The findings revealed the situational and personal anxiety level to be objectively decreased in the short-term group psychotherapy course. The short-term group psychotherapy was proved to bean effective method in anxiety disorders treatment considering indications and limitations.

  13. Explaining Macroeconomic and Term Structure Dynamics Jointly in a Non-linear DSGE Model

    DEFF Research Database (Denmark)

    Andreasen, Martin Møller

    This paper shows how a standard DSGE model can be extended to reproduce the dynamics in the 10 year yield curve for the post-war US economy with a similar degree of precision as in reduced form term structure models. At the same time, we are able to reproduce the dynamics of four key macro...... variables almost perfectly. Our extension of a standard DSGE model is to introduce three non-stationary shocks which allow us to explain interest rates with medium and long maturities without distorting the dynamics of the macroeconomy....

  14. Coordinated approaches to quantify long-term ecosystem dynamics in response to global change

    DEFF Research Database (Denmark)

    Liu, Y.; Melillo, J.; Niu, S.

    2011-01-01

    a coordinated approach that combines long-term, large-scale global change experiments with process studies and modeling. Long-term global change manipulative experiments, especially in high-priority ecosystems such as tropical forests and high-latitude regions, are essential to maximize information gain......Many serious ecosystem consequences of climate change will take decades or even centuries to emerge. Long-term ecological responses to global change are strongly regulated by slow processes, such as changes in species composition, carbon dynamics in soil and by long-lived plants, and accumulation...... to be the most effective strategy to gain the best information on long-term ecosystem dynamics in response to global change....

  15. An improved optimization algorithm of the three-compartment model with spillover and partial volume corrections for dynamic FDG PET images of small animal hearts in vivo

    Science.gov (United States)

    Li, Yinlin; Kundu, Bijoy K.

    2018-03-01

    The three-compartment model with spillover (SP) and partial volume (PV) corrections has been widely used for noninvasive kinetic parameter studies of dynamic 2-[18F] fluoro-2deoxy-D-glucose (FDG) positron emission tomography images of small animal hearts in vivo. However, the approach still suffers from estimation uncertainty or slow convergence caused by the commonly used optimization algorithms. The aim of this study was to develop an improved optimization algorithm with better estimation performance. Femoral artery blood samples, image-derived input functions from heart ventricles and myocardial time-activity curves (TACs) were derived from data on 16 C57BL/6 mice obtained from the UCLA Mouse Quantitation Program. Parametric equations of the average myocardium and the blood pool TACs with SP and PV corrections in a three-compartment tracer kinetic model were formulated. A hybrid method integrating artificial immune-system and interior-reflective Newton methods were developed to solve the equations. Two penalty functions and one late time-point tail vein blood sample were used to constrain the objective function. The estimation accuracy of the method was validated by comparing results with experimental values using the errors in the areas under curves (AUCs) of the model corrected input function (MCIF) and the 18F-FDG influx constant K i . Moreover, the elapsed time was used to measure the convergence speed. The overall AUC error of MCIF for the 16 mice averaged  -1.4  ±  8.2%, with correlation coefficients of 0.9706. Similar results can be seen in the overall K i error percentage, which was 0.4  ±  5.8% with a correlation coefficient of 0.9912. The t-test P value for both showed no significant difference. The mean and standard deviation of the MCIF AUC and K i percentage errors have lower values compared to the previously published methods. The computation time of the hybrid method is also several times lower than using just a stochastic

  16. An analysis of the 'semi-dissipative' terms in the plasma-dynamical equations

    Energy Technology Data Exchange (ETDEWEB)

    Story, L

    1979-01-01

    Consideration is given to the terms arising from collision corrections to the pressures and convective energy flows in the equation of state for the total and electrokinetic pressures and the convective part of the total and relative energy flows obtained by applying hydrodynamical projection techniques to a weakly coupled collisionless plasma near equilibrium. It is shown that the unusual semidissipative contributions to the total pressure deviation from equilibrium and to the convective portion of the total and relative energy flows are zero. The semidissipative contributions in the electrokinetic pressure deviation from equilibrium still remain, however, due to the inclusion of terms usually appearing in the friction vector.

  17. Shutterless non-uniformity correction for the long-term stability of an uncooled long-wave infrared camera

    Science.gov (United States)

    Liu, Chengwei; Sui, Xiubao; Gu, Guohua; Chen, Qian

    2018-02-01

    For the uncooled long-wave infrared (LWIR) camera, the infrared (IR) irradiation the focal plane array (FPA) receives is a crucial factor that affects the image quality. Ambient temperature fluctuation as well as system power consumption can result in changes of FPA temperature and radiation characteristics inside the IR camera; these will further degrade the imaging performance. In this paper, we present a novel shutterless non-uniformity correction method to compensate for non-uniformity derived from the variation of ambient temperature. Our method combines a calibration-based method and the properties of a scene-based method to obtain correction parameters at different ambient temperature conditions, so that the IR camera performance can be less influenced by ambient temperature fluctuation or system power consumption. The calibration process is carried out in a temperature chamber with slowly changing ambient temperature and a black body as uniform radiation source. Enough uniform images are captured and the gain coefficients are calculated during this period. Then in practical application, the offset parameters are calculated via the least squares method based on the gain coefficients, the captured uniform images and the actual scene. Thus we can get a corrected output through the gain coefficients and offset parameters. The performance of our proposed method is evaluated on realistic IR images and compared with two existing methods. The images we used in experiments are obtained by a 384× 288 pixels uncooled LWIR camera. Results show that our proposed method can adaptively update correction parameters as the actual target scene changes and is more stable to temperature fluctuation than the other two methods.

  18. Dynamic Analysis and Circuit Design of a Novel Hyperchaotic System with Fractional-Order Terms

    Directory of Open Access Journals (Sweden)

    Abir Lassoued

    2017-01-01

    Full Text Available A novel hyperchaotic system with fractional-order (FO terms is designed. Its highly complex dynamics are investigated in terms of equilibrium points, Lyapunov spectrum, and attractor forms. It will be shown that the proposed system exhibits larger Lyapunov exponents than related hyperchaotic systems. Finally, to enhance its potential application, a related circuit is designed by using the MultiSIM Software. Simulation results verify the effectiveness of the suggested circuit.

  19. Self-correcting Multigrid Solver

    International Nuclear Information System (INIS)

    Lewandowski, Jerome L.V.

    2004-01-01

    A new multigrid algorithm based on the method of self-correction for the solution of elliptic problems is described. The method exploits information contained in the residual to dynamically modify the source term (right-hand side) of the elliptic problem. It is shown that the self-correcting solver is more efficient at damping the short wavelength modes of the algebraic error than its standard equivalent. When used in conjunction with a multigrid method, the resulting solver displays an improved convergence rate with no additional computational work

  20. Coordinated approaches to quantify long-term ecosystem dynamics in response to global change

    Science.gov (United States)

    Yiqi Luo; Jerry Melillo; Shuli Niu; Claus Beier; James S. Clark; Aime E.T. Classen; Eric Dividson; Jeffrey S. Dukes; R. Dave Evans; Christopher B. Field; Claudia I. Czimczik; Michael Keller; Bruce A. Kimball; Lara M. Kueppers; Richard J. Norby; Shannon L. Pelini; Elise Pendall; Edward Rastetter; Johan Six; Melinda Smith; Mark G. Tjoelker; Margaret S. Torn

    2011-01-01

    Many serious ecosystem consequences of climate change will take decades or even centuries to emerge. Long-term ecological responses to global change are strongly regulated by slow processes, such as changes in species composition, carbon dynamics in soil and by long-lived plants, and accumulation of nutrient capitals. Understanding and predicting these processes...

  1. Crop rotations and poultry litter impact dynamic soil chemical properties and soil biota long-term

    Science.gov (United States)

    Dynamic soil physiochemical interactions with conservation agricultural practices and soil biota are largely unknown. Therefore, this study aims to quantify long-term (12-yr) impacts of cover crops, poultry litter, crop rotations, and conservation tillage and their interactions on soil physiochemica...

  2. Patient Specific Characteristic of Brain Dynamic in Interpretation of Long Term EEG Analysis

    Czech Academy of Sciences Publication Activity Database

    Komárek, V.; Paluš, Milan; Hrnčíř, Z.

    2004-01-01

    Roč. 45, Suppl. 3 (2004), s. 51 ISSN 0013-9580. [European Congress on Epileptology /6./. 30.05.2004-03.06.2004, Vienna] R&D Projects: GA MŠk ME 701 Institutional research plan: CEZ:AV0Z1030915 Keywords : brain dynamic * long term EEG analysis Subject RIV: FH - Neurology

  3. Long-Term Bacterial Dynamics in a Full-Scale Drinking Water Distribution System

    NARCIS (Netherlands)

    Prest, E.I.E.D.; Weissbrodt, D.G.; Hammes, F; van Loosdrecht, Mark C.M.; Vrouwenvelder, J.S.

    2016-01-01

    Large seasonal variations in microbial drinking water quality can occur in distribution networks, but are often not taken into account when evaluating results from short-term water sampling campaigns. Temporal dynamics in bacterial community characteristics were investigated during a two-year

  4. Short-term dynamics of second-growth mixed mesophytic forest strata in West Virginia

    Science.gov (United States)

    Cynthia C. Huebner; Steven L. Stephenson; Harold S. Adams; Gary W. Miller

    2007-01-01

    The short-term dynamics of mixed mesophytic forest strata in West Virginia were examined using similarity analysis and linear correlation of shared ordination space. The overstory tree, understory tree, shrub/vine, and herb strata were stable over a six year interval, whereas the tree seedling and sapling strata were unstable. All strata but the shrub/vine and tree...

  5. Optimization of mixed quantum-classical dynamics: Time-derivative coupling terms and selected couplings

    International Nuclear Information System (INIS)

    Pittner, Jiri; Lischka, Hans; Barbatti, Mario

    2009-01-01

    The usage of time-derivative non-adiabatic coupling terms and partially coupled time-dependent equations are investigated to accelerate non-adiabatic dynamics simulations at multireference configuration interaction (MRCI) level. The quality of the results and computational costs are compared against non-adiabatic benchmark dynamics calculations using non-adiabatic coupling vectors. In the comparison between the time-derivative couplings and coupling vectors, deviations in the adiabatic population of individual trajectories were observed in regions of rapid variation of the coupling terms. They, however, affected the average adiabatic population to only about 5%. For small multiconfiguration spaces, dynamics with time-derivative couplings are significantly faster than those with coupling vectors. This relation inverts for larger configuration spaces. The use of the partially coupled equations approach speeds up the simulations significantly while keeping the deviations in the population below few percent. Imidazole and the methaniminium cation are used as test examples

  6. Correction of the equilibrium temperature caused by slight evaporation of water in protein crystal growth cells during long-term space experiments at International Space Station.

    Science.gov (United States)

    Fujiwara, Takahisa; Suzuki, Yoshihisa; Yoshizaki, Izumi; Tsukamoto, Katsuo; Murayama, Kenta; Fukuyama, Seijiro; Hosokawa, Kouhei; Oshi, Kentaro; Ito, Daisuke; Yamazaki, Tomoya; Tachibana, Masaru; Miura, Hitoshi

    2015-08-01

    The normal growth rates of the {110} faces of tetragonal hen egg-white lysozyme crystals, R, were measured as a function of the supersaturation σ parameter using a reflection type interferometer under μG at the International Space Station (NanoStep Project). Since water slightly evaporated from in situ observation cells during a long-term space station experiment for several months, equilibrium temperature T(e) changed, and the actual σ, however, significantly increased mainly due to the increase in salt concentration C(s). To correct σ, the actual C(s) and protein concentration C(p), which correctly represent the measured T(e) value in space, were first calculated. Second, a new solubility curve with the corrected C(s) was plotted. Finally, the revised σ was obtained from the new solubility curve. This correction method successfully revealed that the 2.8% water was evaporated from the solution, leading to 2.8% increase in the C(s) and C(p) of the solution.

  7. How to correct for long-term externalities of large-scale wind power development by a capacity mechanism?

    International Nuclear Information System (INIS)

    Cepeda, Mauricio; Finon, Dominique

    2013-01-01

    This paper deals with the practical problems related to long-term security of supply in electricity markets in the presence of large-scale wind power development. The success of recent renewable promotion schemes adds a new dimension to ensuring long-term security of supply: it necessitates designing second-best policies to prevent large-scale wind power development from distorting long-run equilibrium prices and investments in conventional generation and in particular in peaking units. We rely upon a long-term simulation model which simulates electricity market players' investment decisions in a market regime and incorporates large-scale wind power development in the presence of either subsidized or market driven development scenarios. We test the use of capacity mechanisms to compensate for long-term effects of large-scale wind power development on prices and reliability of supply. The first finding is that capacity mechanisms can help to reduce the social cost of large scale wind power development in terms of decrease of loss of load probability. The second finding is that, in a market-based wind power deployment without subsidy, wind generators are penalised for insufficient contribution to the long term system's reliability. - Highlights: • We model power market players’ investment decisions incorporating wind power. • We examine two market designs: an energy-only market and a capacity mechanism. • We test two types of wind power development paths: subsidised and market-driven. • Capacity mechanisms compensate for the externalities of wind power developments

  8. How to correct long-term system externality of large scale wind power development by a capacity mechanism?

    International Nuclear Information System (INIS)

    Cepeda, Mauricio; Finon, Dominique

    2013-04-01

    This paper deals with the practical problems related to long-term security of supply in electricity markets in the presence of large-scale wind power development. The success of renewable promotion schemes adds a new dimension to ensuring long-term security of supply. It necessitates designing second-best policies to prevent large-scale wind power development from distorting long-run equilibrium prices and investments in conventional generation and in particular in peaking units. We rely upon a long-term simulation model which simulates electricity market players' investment decisions in a market regime and incorporates large-scale wind power development either in the presence of either subsidised wind production or in market-driven development. We test the use of capacity mechanisms to compensate for the long-term effects of large-scale wind power development on the system reliability. The first finding is that capacity mechanisms can help to reduce the social cost of large scale wind power development in terms of decrease of loss of load probability. The second finding is that, in a market-based wind power deployment without subsidy, wind generators are penalized for insufficient contribution to the long term system's reliability. (authors)

  9. Corrections of arterial input function for dynamic H215O PET to assess perfusion of pelvic tumours: arterial blood sampling versus image extraction

    International Nuclear Information System (INIS)

    Luedemann, L; Sreenivasa, G; Michel, R; Rosner, C; Plotkin, M; Felix, R; Wust, P; Amthauer, H

    2006-01-01

    Assessment of perfusion with 15 O-labelled water (H 2 15 O) requires measurement of the arterial input function (AIF). The arterial time activity curve (TAC) measured using the peripheral sampling scheme requires corrections for delay and dispersion. In this study, parametrizations with and without arterial spillover correction for fitting of the tissue curve are evaluated. Additionally, a completely noninvasive method for generation of the AIF from a dynamic positron emission tomography (PET) acquisition is applied to assess perfusion of pelvic tumours. This method uses a volume of interest (VOI) to extract the TAC from the femoral artery. The VOI TAC is corrected for spillover using a separate tissue TAC and for recovery by determining the recovery coefficient on a coregistered CT data set. The techniques were applied in five patients with pelvic tumours who underwent a total of 11 examinations. Delay and dispersion correction of the blood TAC without arterial spillover correction yielded in seven examinations solutions inconsistent with physiology. Correction of arterial spillover increased the fitting accuracy and yielded consistent results in all patients. Generation of an AIF from PET image data was investigated as an alternative to arterial blood sampling and was shown to have an intrinsic potential to determine the AIF noninvasively and reproducibly. The AIF extracted from a VOI in a dynamic PET scan was similar in shape to the blood AIF but yielded significantly higher tissue perfusion values (mean of 104.0 ± 52.0%) and lower partition coefficients (-31.6 ± 24.2%). The perfusion values and partition coefficients determined with the VOI technique have to be corrected in order to compare the results with those of studies using a blood AIF

  10. Crown lengthening procedure following intentional endodontic therapy for correction of supra-erupted posterior teeth: Case series with long-term follow-up

    Science.gov (United States)

    Patil, Shruti Arun; Kulkarni, Sudhindra; Thakur, Srinath; Naik, Balaram

    2016-01-01

    Context: The crown lengthening procedure (CLP) is routinely carried out to correct gingival levels and achieve esthetic contours and adequate crown lengths for restorative purposes. Though the short-term outcomes have been found to be stable, long-term results are not much reported. Aims: To evaluate the long-term stability of the marginal bone levels, gingival levels, and the status of the teeth, which underwent endodontic therapy, followed by CLP and final restorations. Settings and Design: Institutional setting, long-term case series. Materials and Methods: Case records of the patients who underwent CLP and endodontic therapy for corrections of the supra-erupted teeth to regain the lost interocclusal spaces were retrieved, and the cases with complete set of the clinical and radiographs were taken. All the cases were recalled and bone levels on the radiographs, bleeding on probing, probing pocket depths, and changes in the soft tissue margins were evaluated. Statistical Analysis Used: Descriptive analysis. Results: A total of 25 teeth had undergone CLP and endodontic therapy and final restorations for a minimum of 24 months. The mean post-restorative duration was 50.8 ± 22.48 months (range 24–96 months). All the teeth were functional and asymptomatic with 100% survival. Interdental bone loss of 1 mm, probing pockets of 5 mm, and 1 mm buccal recession were observed in 16% of the sites. The amount of interocclusal space regained was adequate to restore the missing teeth in the opposing arch. Conclusions: The CLP is a predictive procedure for correction of supra-erupted teeth. The survival of the teeth that underwent the procedure in the present study was 100% over 24–96 months. PMID:27041850

  11. DMPD: Type I interferon [corrected] gene induction by the interferon regulatory factorfamily of transcription factors. [Dynamic Macrophage Pathway CSML Database

    Lifescience Database Archive (English)

    Full Text Available 16979567 Type I interferon [corrected] gene induction by the interferon regulatory factorfamily...ng) (.svg) (.html) (.csml) Show Type I interferon [corrected] gene induction by the interferon regulatory factorfamily...orrected] gene induction by the interferon regulatory factorfamily of transcription factors. Authors Honda K

  12. Erratum: Correction to: Long- and Mid-Term Variations of the Soft X-ray Flare Character in Solar Cycles

    Science.gov (United States)

    Chertok, I. M.; Belov, A. V.

    2018-03-01

    Correction to: Solar Phys https://doi.org/10.1007/s11207-017-1169-1 We found an important error in the text of our article. On page 6, the second sentence of Section 3.2 "We studied the variations in soft X-ray flare characteristics in more detail by averaging them within the running windows of ± one Carrington rotation with a step of two rotations." should instead read "We studied the variations in soft X-ray flare characteristics in more detail by averaging them within the running windows of ± 2.5 Carrington rotations with a step of two rotations." We regret the inconvenience. The online version of the original article can be found at https://doi.org/10.1007/s11207-017-1169-1

  13. Endogeneity, Time-Varying Coefficients, and Incorrect vs. Correct Ways of Specifying the Error Terms of Econometric Models

    Directory of Open Access Journals (Sweden)

    P.A.V.B. Swamy

    2017-02-01

    Full Text Available Using the net effect of all relevant regressors omitted from a model to form its error term is incorrect because the coefficients and error term of such a model are non-unique. Non-unique coefficients cannot possess consistent estimators. Uniqueness can be achieved if; instead; one uses certain “sufficient sets” of (relevant regressors omitted from each model to represent the error term. In this case; the unique coefficient on any non-constant regressor takes the form of the sum of a bias-free component and omitted-regressor biases. Measurement-error bias can also be incorporated into this sum. We show that if our procedures are followed; accurate estimation of bias-free components is possible.

  14. Instrument Correction and Dynamic Site Profile Validation at the Central United States Seismic Observatory, New Madrid Seismic Zone

    Science.gov (United States)

    Brengman, C.; Woolery, E. W.; Wang, Z.; Carpenter, S.

    2016-12-01

    The Central United States Seismic Observatory (CUSSO) is a vertical seismic array located in southwestern Kentucky within the New Madrid seismic zone. It is intended to describe the effects of local geology, including thick sediment overburden, on seismic-wave propagation, particularly strong-motion. The three-borehole array at CUSSO is composed of seismic sensors placed on the surface, and in the bedrock at various depths within the 585 m thick sediment overburden. The array's deep borehole provided a unique opportunity in the northern Mississippi embayment for the direct geological description and geophysical measurement of the complete late Cretaceous-Quaternary sediment column. A seven layer, intra-sediment velocity model is interpreted from the complex, inhomogeneous stratigraphy. The S- and P-wave sediment velocities range between 160 and 875 m/s and between 1000 and 2300 m/s, respectively, with bedrock velocities of 1452 and 3775 m/s, respectively. Cross-correlation and direct comparisons were used to filter out the instrument response and determine the instrument orientation, making CUSSO data ready for analysis, and making CUSSO a viable calibration site for other free-field sensors in the area. The corrected bedrock motions were numerically propagated through the CUSSO soil profile (transfer function) and compared, in terms of both peak acceleration and amplitude spectra, to the recorded surface observations. Initial observations reveal a complex spectral mix of amplification and de-amplification across the array, indicating the site effect in this deep sediment setting is not simply generated by the shallowest layers.

  15. Exploring the dynamics of balance data - movement variability in terms of drift and diffusion

    Energy Technology Data Exchange (ETDEWEB)

    Gottschall, Julia [Institute of Physics, University of Oldenburg, D-26111 Oldenburg (Germany)], E-mail: julia.gottschall@uni-oldenburg.de; Peinke, Joachim [Institute of Physics, University of Oldenburg, D-26111 Oldenburg (Germany)], E-mail: peinke@uni-oldenburg.de; Lippens, Volker [Department of Human Movement, University of Hamburg, Moller Street 10, D-20148 Hamburg (Germany)], E-mail: vlippens@uni-hamburg.de; Nagel, Volker [Department of Human Movement, University of Hamburg, Moller Street 10, D-20148 Hamburg (Germany)

    2009-02-23

    We introduce a method to analyze postural control on a balance board by reconstructing the underlying dynamics in terms of a Langevin model. Drift and diffusion coefficients are directly estimated from the data and fitted by a suitable parametrization. The governing parameters are utilized to evaluate balance performance and the impact of supra-postural tasks on it. We show that the proposed method of analysis gives not only self-consistent results but also provides a plausible model for the reconstruction of balance dynamics.

  16. Exploring the dynamics of balance data - movement variability in terms of drift and diffusion

    International Nuclear Information System (INIS)

    Gottschall, Julia; Peinke, Joachim; Lippens, Volker; Nagel, Volker

    2009-01-01

    We introduce a method to analyze postural control on a balance board by reconstructing the underlying dynamics in terms of a Langevin model. Drift and diffusion coefficients are directly estimated from the data and fitted by a suitable parametrization. The governing parameters are utilized to evaluate balance performance and the impact of supra-postural tasks on it. We show that the proposed method of analysis gives not only self-consistent results but also provides a plausible model for the reconstruction of balance dynamics

  17. Short- and long-term variations in non-linear dynamics of heart rate variability

    DEFF Research Database (Denmark)

    Kanters, J K; Højgaard, M V; Agner, E

    1996-01-01

    OBJECTIVES: The purpose of the study was to investigate the short- and long-term variations in the non-linear dynamics of heart rate variability, and to determine the relationships between conventional time and frequency domain methods and the newer non-linear methods of characterizing heart rate...... rate and describes mainly linear correlations. Non-linear predictability is correlated with heart rate variability measured as the standard deviation of the R-R intervals and the respiratory activity expressed as power of the high-frequency band. The dynamics of heart rate variability changes suddenly...

  18. Stability Analysis on Sparsely Encoded Associative Memory with Short-Term Synaptic Dynamics

    Science.gov (United States)

    Xu, Muyuan; Katori, Yuichi; Aihara, Kazuyuki

    This study investigates the stability of sparsely encoded associative memory in a network composed of stochastic neurons. The incorporation of short-term synaptic dynamics significantly changes the stability with respect to synaptic properties. Various states including static and oscillatory states are found in the network dynamics. Specifically, the sparseness of memory patterns raises the problem of spurious states. A mean field model is used to analyze the detailed structure in the stability and show that the performance of memory retrieval is recovered by appropriate feedback.

  19. [Radiometers performance attenuation and data correction in long-term observation of total radiation and photosynthetically active radiation in typical forest ecosystems in China].

    Science.gov (United States)

    Zhu, Zhi-Lin; Sun, Xiao-Min; Yu, Gui-Rui; Wen, Xue-Fa; Zhang, Yi-Ping; Han, Shi-Jie; Yan, Jun-Hua; Wang, Hui-Min

    2011-11-01

    Based on the total radiation and photosynthetically active radiation (PAR) observations with net radiometer (CNR1) and quantum sensor (Li-190SB) in 4 ChinaFLUX forest sites (Changbaishan, Qianyanzhou, Dinghushan, and Xishuangbanna) in 2003-2008, this paper analyzed the uncertainties and the radiometers performance changes in long-term and continuous field observation. The results showed that the 98% accuracy of the total radiation measured with CNR1 (Q(cNR1)) could satisfy the technical criterion for the sites except Xishuangbanna where the Q(CNR1) was averagely about 7% lower than Q(CM11), the radiation measured with high accuracy pyranometer CM11. For most sites, though the temperature had definite effects on the performance of CNR1, the effects were still within the allowable range of the accuracy of the instrument. Besides temperature, the seasonal fog often occurred in tropical rain forests in Xishuangbanna also had effects on the performance of CNR1. Based on the long-term variations of PAR, especially its ratio to total radiation in the 4 sites, it was found that quantum sensor (Li-190SB) had obvious performance attenuation, with the mean annual attenuation rate being about 4%. To correct the observation error caused by Li-190SB, an attempt was made to give a post-correction of the PAR observations, which could basically eliminate the quantum sensor's performance attenuation due to long-term field measurement.

  20. In-situ Study of Dynamic Phenomena at Metal Nanosolder Interfaces Using Aberration Corrected Scanning Transmission Electron Microcopy.

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Ping

    2014-10-01

    Controlling metallic nanoparticle (NP) interactions plays a vital role in the development of new joining techniques (nanosolder) that bond at lower processing temperatures but remain viable at higher temperatures. The pr imary objective of this project is t o develop a fundamental understanding of the actual reaction processes, associated atomic mechanisms, and the resulting microstructure that occur during thermally - driven bond formation concerning metal - metal nano - scale (%3C50nm) interfaces. In this LDRD pr oject, we have studied metallic NPs interaction at the elevated temperatures by combining in - situ transmission electron microscopy (TEM ) using an aberration - corrected scanning transmission electron microscope (AC - STEM) and atomic - scale modeling such as m olecular dynamic (MD) simulations. Various metallic NPs such as Ag, Cu and Au are synthesized by chemical routines. Numerous in - situ e xperiments were carried out with focus of the research on study of Ag - Cu system. For the first time, using in - situ STEM he ating experiments , we directly observed t he formation of a 3 - dimensional (3 - D) epitaxial Cu - Ag core - shell nanoparticle during the thermal interaction of Cu and Ag NPs at elevated temperatures (150 - 300 o C). The reaction takes place at temperatures as low as 150 o C and was only observed when care was taken to circumvent the effects of electron beam irradiation during STEM imaging. Atomic - scale modeling verified that the Cu - Ag core - shell structure is energetically favored, and indicated that this phenomenon is a nano - scale effect related to the large surface - to - volume ratio of the NPs. The observation potentially can be used for developing new nanosolder technology that uses Ag shell as the "glue" that stic ks the particles of Cu together. The LDRD has led to several journal publications and numerous conference presentations, and a TA. In addition, we have developed new TEM characterization techniques and phase

  1. Synaptic scaling enables dynamically distinct short- and long-term memory formation.

    Directory of Open Access Journals (Sweden)

    Christian Tetzlaff

    2013-10-01

    Full Text Available Memory storage in the brain relies on mechanisms acting on time scales from minutes, for long-term synaptic potentiation, to days, for memory consolidation. During such processes, neural circuits distinguish synapses relevant for forming a long-term storage, which are consolidated, from synapses of short-term storage, which fade. How time scale integration and synaptic differentiation is simultaneously achieved remains unclear. Here we show that synaptic scaling - a slow process usually associated with the maintenance of activity homeostasis - combined with synaptic plasticity may simultaneously achieve both, thereby providing a natural separation of short- from long-term storage. The interaction between plasticity and scaling provides also an explanation for an established paradox where memory consolidation critically depends on the exact order of learning and recall. These results indicate that scaling may be fundamental for stabilizing memories, providing a dynamic link between early and late memory formation processes.

  2. Synaptic scaling enables dynamically distinct short- and long-term memory formation.

    Science.gov (United States)

    Tetzlaff, Christian; Kolodziejski, Christoph; Timme, Marc; Tsodyks, Misha; Wörgötter, Florentin

    2013-10-01

    Memory storage in the brain relies on mechanisms acting on time scales from minutes, for long-term synaptic potentiation, to days, for memory consolidation. During such processes, neural circuits distinguish synapses relevant for forming a long-term storage, which are consolidated, from synapses of short-term storage, which fade. How time scale integration and synaptic differentiation is simultaneously achieved remains unclear. Here we show that synaptic scaling - a slow process usually associated with the maintenance of activity homeostasis - combined with synaptic plasticity may simultaneously achieve both, thereby providing a natural separation of short- from long-term storage. The interaction between plasticity and scaling provides also an explanation for an established paradox where memory consolidation critically depends on the exact order of learning and recall. These results indicate that scaling may be fundamental for stabilizing memories, providing a dynamic link between early and late memory formation processes.

  3. Method and System for Dynamic Automated Corrections to Weather Avoidance Routes for Aircraft in En Route Airspace

    Science.gov (United States)

    McNally, B. David (Inventor); Erzberger, Heinz (Inventor); Sheth, Kapil (Inventor)

    2015-01-01

    A dynamic weather route system automatically analyzes routes for in-flight aircraft flying in convective weather regions and attempts to find more time and fuel efficient reroutes around current and predicted weather cells. The dynamic weather route system continuously analyzes all flights and provides reroute advisories that are dynamically updated in real time while the aircraft are in flight. The dynamic weather route system includes a graphical user interface that allows users to visualize, evaluate, modify if necessary, and implement proposed reroutes.

  4. Long-Term Outcome of Mustard/Senning Correction for Transposition of the Great Arteries in Sweden and Denmark

    DEFF Research Database (Denmark)

    Vejlstrup, Niels; Sørensen, Keld; Mattsson, Eva

    2015-01-01

    and leaves the right ventricle as the systemic ventricle. The Mustard and Senning cohort is now well into adulthood and we begin to see the long-term outcome. METHODS AND RESULTS: All the 6 surgical centers that performed Mustard and Senning operations in Sweden and Denmark identified all operated TGA...... patients. Information about death was obtained in late 2007 and early 2008 from the Danish and Swedish Centralised Civil Register by using the patients' unique national Civil Registration Numbers. Four hundred sixty-eight patients undergoing the atrial switch operation were identified. Perioperative 30-day...... of long-term outcome (hazard ratio, 1.90; 95% confidence interval, 1.05-3.46, P=0.04), once the TGA patient has survived the perioperative period. The risk of reoperation was correlated to the presence of associated defects and where the first Mustard/Senning operation was performed. CONCLUSIONS: The long...

  5. Dynamic sensorimotor planning during long-term sequence learning: the role of variability, response chunking and planning errors.

    Science.gov (United States)

    Verstynen, Timothy; Phillips, Jeff; Braun, Emily; Workman, Brett; Schunn, Christian; Schneider, Walter

    2012-01-01

    Many everyday skills are learned by binding otherwise independent actions into a unified sequence of responses across days or weeks of practice. Here we looked at how the dynamics of action planning and response binding change across such long timescales. Subjects (N = 23) were trained on a bimanual version of the serial reaction time task (32-item sequence) for two weeks (10 days total). Response times and accuracy both showed improvement with time, but appeared to be learned at different rates. Changes in response speed across training were associated with dynamic changes in response time variability, with faster learners expanding their variability during the early training days and then contracting response variability late in training. Using a novel measure of response chunking, we found that individual responses became temporally correlated across trials and asymptoted to set sizes of approximately 7 bound responses at the end of the first week of training. Finally, we used a state-space model of the response planning process to look at how predictive (i.e., response anticipation) and error-corrective (i.e., post-error slowing) processes correlated with learning rates for speed, accuracy and chunking. This analysis yielded non-monotonic association patterns between the state-space model parameters and learning rates, suggesting that different parts of the response planning process are relevant at different stages of long-term learning. These findings highlight the dynamic modulation of response speed, variability, accuracy and chunking as multiple movements become bound together into a larger set of responses during sequence learning.

  6. Regulatory competence and social communication in term and preterm infants at 12 months corrected age. Results from a randomized controlled trial.

    Science.gov (United States)

    Olafsen, Kåre S; Rønning, John A; Handegård, Bjørn Helge; Ulvund, Stein Erik; Dahl, Lauritz Bredrup; Kaaresen, Per Ivar

    2012-02-01

    Temperamental regulatory competence and social communication in term and preterm infants at 12 months corrected age was studied in a randomized controlled intervention trial aimed at enhancing maternal sensitive responsiveness. Surviving infants communication with the Early Social Communication Scales. Preterm intervention infants with low regulatory competence had higher responding to joint attention than preterm control infants. A sensitizing intervention may moderate the association between temperament and social communication, and thus allow an alternative functional outlet for preterm infants low in regulatory competence. The finding may have implications for conceptualizations of the role of early sensitizing interventions in promoting important developmental outcomes for premature infants. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. On The Ubiquity of Nonstationary Fluvial Suspended Sediment Dynamics: A Call for Long Term Monitoring and Dynamical Sediment Management Strategies

    Science.gov (United States)

    Gray, A. B.

    2017-12-01

    Watersheds with sufficient monitoring data have been predominantly found to display nonstationary suspended sediment dynamics, whereby the relationship between suspended sediment concentration and discharge changes over time. Despite the importance of suspended sediment as a keystone of geophysical and biochemical processes, and as a primary mediator of water quality, stationary behavior remains largely assumed in the context of these applications. This study presents an investigation into the time dependent behavior of small mountainous rivers draining the coastal ranges of the western continental US over interannual to interdecadal time scales. Of the 250+ small coastal (drainage area systems. Temporal patterns of non-stationary behavior provided some evidence for spatial coherence, which may be related to synoptic hydro-metrological patterns and regional scale changes in land use patterns. However, the results also highlight the complex, integrative nature of watershed scale fluvial suspended sediment dynamics. This underscores the need for in-depth, forensic approaches for initial processes identification, which require long term, high resolution monitoring efforts in order to adequately inform management. The societal implications of nonstationary sediment dynamics and their controls were further explored through the case of California, USA, where over 150 impairment listings have resulted in more than 50 sediment TMDLs, only 3 of which are flux based - none of which account for non-stationary behavior.

  8. Modeling the Interest Rate Term Structure: Derivatives Contracts Dynamics and Evaluation

    Directory of Open Access Journals (Sweden)

    Pedro L. Valls Pereira

    2005-06-01

    Full Text Available This article deals with a model for the term structure of interest rates and the valuation of derivative contracts directly dependent on it. The work is of a theoretical nature and deals, exclusively, with continuous time models, making ample use of stochastic calculus results and presents original contributions that we consider relevant to the development of the fixed income market modeling. We develop a new multifactorial model of the term structure of interest rates. The model is based on the decomposition of the yield curve into the factors level, slope, curvature, and the treatment of their collective dynamics. We show that this model may be applied to serve various objectives: analysis of bond price dynamics, valuation of derivative contracts and also market risk management and formulation of operational strategies which is presented in another article.

  9. An efficient approach to the evaluation of mid-term dynamic processes in power systems

    Energy Technology Data Exchange (ETDEWEB)

    Zivanovic, R M [Pretoria Technikon (South Africa); Popovic, D P [Nikola Tesla Inst., Belgrade (Yugoslavia). Power System Dept.

    1993-01-01

    This paper presents some improvements in the methodology for analysing mid-term dynamic processes in power systems. These improvements are: an efficient application of the hierarchical clustering algorithm to adaptive identification of coherent generator groups and a significant reduction of the mathematical model, on the basis of monitoring the state of only one generator in one of the established coherent groups. This enables a flexible, simple and fast transformation from the full to the reduced model and vice versa, a significant acceleration of the simulation while keeping the desired accuracy and the automatic use in continual dynamic analysis. Verification of the above mentioned contributions was performed on examples of the dynamic analysis of New England and Yugoslav power systems. (author)

  10. Long-term social dynamics drive loss of function in pathogenic bacteria

    DEFF Research Database (Denmark)

    Breum Andersen, Sandra; Marvig, Rasmus Lykke; Molin, Søren

    2015-01-01

    Laboratory experiments show that social interactions between bacterial cells can drive evolutionary change at the population level, but significant challenges limit attempts to assess the relevance of these findings to natural populations, where selection pressures are unknown. We have increasingly...... sophisticated methods for monitoring phenotypic and genotypic dynamics in bacteria causing infectious disease, but in contrast, we lack evidence-based adaptive explanations for those changes. Evolutionary change during infection is often interpreted as host adaptation, but this assumption neglects to consider...... social dynamics shown to drive evolutionary change in vitro. We provide evidence to show that long-term behavioral dynamics observed in a pathogen are driven by selection to outcompete neighboring conspecific cells through social interactions. We find that Pseudomonas aeruginosa bacteria, causing lung...

  11. Nonlinear Dynamical Modes as a Basis for Short-Term Forecast of Climate Variability

    Science.gov (United States)

    Feigin, A. M.; Mukhin, D.; Gavrilov, A.; Seleznev, A.; Loskutov, E.

    2017-12-01

    We study abilities of data-driven stochastic models constructed by nonlinear dynamical decomposition of spatially distributed data to quantitative (short-term) forecast of climate characteristics. We compare two data processing techniques: (i) widely used empirical orthogonal function approach, and (ii) nonlinear dynamical modes (NDMs) framework [1,2]. We also make comparison of two kinds of the prognostic models: (i) traditional autoregression (linear) model and (ii) model in the form of random ("stochastic") nonlinear dynamical system [3]. We apply all combinations of the above-mentioned data mining techniques and kinds of models to short-term forecasts of climate indices based on sea surface temperature (SST) data. We use NOAA_ERSST_V4 dataset (monthly SST with space resolution 20 × 20) covering the tropical belt and starting from the year 1960. We demonstrate that NDM-based nonlinear model shows better prediction skill versus EOF-based linear and nonlinear models. Finally we discuss capability of NDM-based nonlinear model for long-term (decadal) prediction of climate variability. [1] D. Mukhin, A. Gavrilov, E. Loskutov , A.Feigin, J.Kurths, 2015: Principal nonlinear dynamical modes of climate variability, Scientific Reports, rep. 5, 15510; doi: 10.1038/srep15510. [2] Gavrilov, A., Mukhin, D., Loskutov, E., Volodin, E., Feigin, A., & Kurths, J., 2016: Method for reconstructing nonlinear modes with adaptive structure from multidimensional data. Chaos: An Interdisciplinary Journal of Nonlinear Science, 26(12), 123101. [3] Ya. Molkov, D. Mukhin, E. Loskutov, A. Feigin, 2012: Random dynamical models from time series. Phys. Rev. E, Vol. 85, n.3.

  12. Long-term dynamics of chlorophyll concentration in the ocean surface layer (by space data)

    Science.gov (United States)

    Shevyrnogov, A.; Vysotskaya, G.

    To preserve the biosphere and to use it efficiently, it is necessary to gain a deep insight into the dynamics of the primary production process on our planet. Variability of chlorophyll concentration in the ocean is one of the most important components of this process. These investigations are, however, very labor-consuming, because of the difficulties related to the accessibility of the water surface and its large size. In this work long-term changes in chlorophyll concentration in the surface layer of the ocean have been analyzed on the basis of the CZCS data for 7.5 years from 1979 to 1986 and the SeaWiFS data from 1997 to 2004. It has been shown that the average chlorophyll concentration calculated in all investigated areas varies moderately. However, when analyzing spatially local trends, the areas have been detected that have significant rise and fall of chlorophyll concentrations. Some interesting features of the long-term dynamics of chlorophyll concentration have been found. The opposite directions of long-term trends (essential increase or decrease) cannot be explained only by large-scale hydrological phenomena in the ocean (currents, upwellings, etc.). The measured chlorophyll concentration results from the balance between production and destruction processes. Which process dominates is determined by various hydrophysical, hydrobiological, and climatic processes, leading to sharp rises or falls of the concentration. It is important to estimate the scale of the areas in which this or that process dominates. Therefore, the study addresses not only the dynamics of the mean value but also the dynamics of the areas in which the dominance of certain factors has led to a sharp fall or rise in chlorophyll concentration. Thus, the obtained results can be used to estimate long-term changes in the ocean biota.

  13. Dynamic and Long-term Linkages among Growth, Inequality and Poverty in Developing Countries

    OpenAIRE

    Katsushi S. Imai; Raghav Gaiha

    2014-01-01

    Abstract Drawing upon a cross-country panel data for developing countries, the present study sheds new empirical light on dynamic and long-term linkages among growth, inequality and poverty. First, agricultural sector growth is found to be consistently the most important factor in reducing inequality and poverty not only through its direct effects but also through its indirect effects. Second, there is a significant and negative association between inequality and GDP per capita, with macro in...

  14. Understanding long-term fruit fly (Diptera: Tephritidae) population dynamics: implications for areawide management.

    Science.gov (United States)

    Aluja, Martín; Ordano, Mariano; Guillén, Larissa; Rull, Juan

    2012-06-01

    Fruit flies (Diptera: Tephritidae) are devastating agricultural pests worldwide but studies on their long-term population dynamics are sparse. Our aim was to determine the mechanisms driving long-term population dynamics as a prerequisite for ecologically based areawide pest management. The population density of three pestiferous Anastrepha species [Anastrepha ludens (Loew), Anastrepha obliqua (Macquart), and Anastrepha serpentina (Wiedemann)] was determined in grapefruit (Citrus x paradisi Macfad.), mango (Mangifera indica L.), and sapodilla [Manilkara zapota (L.) P. Royen] orchards in central Veracruz, México, on a weekly basis over an 11-yr period. Fly populations exhibited relatively stable dynamics over time. Population dynamics were mainly driven by a direct density-dependent effect and a seasonal feedback process. We discovered direct and delayed influences that were correlated with both local (rainfall and air temperature) and global climatic variation (El Niño Southern Oscillation [ENSO] and North Atlantic Oscillation [NAO]), and detected differences among species and location of orchards with respect to the magnitude and nature (linear or nonlinear) of the observed effects, suggesting that highly mobile pest outbreaks become uncertain in response to significant climatic events at both global and local levels. That both NAO and ENSO affected Anastrepha population dynamics, coupled with the high mobility of Anastrepha adults and the discovery that when measured as rate of population change, local population fluctuations exhibited stable dynamics over time, suggests potential management scenarios for the species studied lie beyond the local scale and should be approached from an areawide perspective. Localized efforts, from individual growers will probably prove ineffective, and nonsustainable.

  15. Normal Cerebellar Growth by Using Three-dimensional US in the Preterm Infant from Birth to Term-corrected Age.

    Science.gov (United States)

    Benavente-Fernández, Isabel; Rodríguez-Zafra, Enrique; León-Martínez, Jesús; Jiménez-Gómez, Gema; Ruiz-González, Estefanía; Fernández-Colina, Rosalía Campuzano; Lechuga-Sancho, Alfonso M; Lubián-López, Simón P

    2018-04-03

    Purpose To establish cross-sectional and longitudinal reference values for cerebellar size in preterm infants with normal neuroimaging findings and normal 2-year neurodevelopmental outcome by using cranial ultrasonography (US). Materials and Methods This prospective study consecutively enrolled preterm infants admitted to a neonatal intensive care unit from June 2011 to June 2014 with a birth weight of less than or equal to 1500 g and/or gestational age (GA) of less than or equal to 32 weeks. They underwent weekly cranial US from birth to term-equivalent age and magnetic resonance (MR) imaging at term-equivalent age. The infants underwent neurodevelopmental assessments at age 2 years with Bayley Scales of Infant and Toddler Development, 3rd edition (BSID-III). Patients with adverse outcomes (death or abnormal neuroimaging findings and/or BSID-III score of growth in preterm infants, which may be included in routine cranial US. © RSNA, 2018 Online supplemental material is available for this article.

  16. Extended-Term Dynamic Simulations with High Penetrations of Photovoltaic Generation.

    Energy Technology Data Exchange (ETDEWEB)

    Concepcion, Ricky James [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Elliott, Ryan Thomas [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Donnelly, Matt [Montana Tech., Butte, MT (United States); Sanchez-Gasca, Juan [GE Energy, Schenectady, NY (United States)

    2016-01-01

    The uncontrolled intermittent availability of renewable energy sources makes integration of such devices into today's grid a challenge. Thus, it is imperative that dynamic simulation tools used to analyze power system performance are able to support systems with high amounts of photovoltaic (PV) generation. Additionally, simulation durations expanding beyond minutes into hours must be supported. This report aims to identify the path forward for dynamic simulation tools to accom- modate these needs by characterizing the properties of power systems (with high PV penetration), analyzing how these properties affect dynamic simulation software, and offering solutions for po- tential problems. We present a study of fixed time step, explicit numerical integration schemes that may be more suitable for these goals, based on identified requirements for simulating high PV penetration systems. We also present the alternative of variable time step integration. To help determine the characteristics of systems with high PV generation, we performed small signal sta- bility studies and time domain simulations of two representative systems. Along with feedback from stakeholders and vendors, we identify the current gaps in power system modeling including fast and slow dynamics and propose a new simulation framework to improve our ability to model and simulate longer-term dynamics.

  17. Long-term correction of obesity and diabetes in genetically obese mice by a single intramuscular injection of recombinant adeno-associated virus encoding mouse leptin

    Science.gov (United States)

    Murphy, John E.; Zhou, Shangzhen; Giese, Klaus; Williams, Lewis T.; Escobedo, Jaime A.; Dwarki, Varavani J.

    1997-01-01

    The ob/ob mouse is genetically deficient in leptin and exhibits a phenotype that includes obesity and non-insulin-dependent diabetes melitus. This phenotype closely resembles the morbid obesity seen in humans. In this study, we demonstrate that a single intramuscular injection of a recombinant adeno-associated virus (AAV) vector encoding mouse leptin (rAAV-leptin) in ob/ob mice leads to prevention of obesity and diabetes. The treated animals show normalization of metabolic abnormalities including hyperglycemia, insulin resistance, impaired glucose tolerance, and lethargy. The effects of a single injection have lasted through the 6-month course of the study. At all time points measured the circulating levels of leptin in the serum were similar to age-matched control C57 mice. These results demonstrate that maintenance of normal levels of leptin (2–5 ng/ml) in the circulation can prevent both the onset of obesity and associated non-insulin-dependent diabetes. Thus a single injection of a rAAV vector expressing a therapeutic gene can lead to complete and long-term correction of a genetic disorder. Our study demonstrates the long-term correction of a disease caused by a genetic defect and proves the feasibility of using rAAV-based vectors for the treatment of chronic disorders like obesity. PMID:9391128

  18. Dynamic analysis and electronic circuit implementation of a novel 3D autonomous system without linear terms

    Science.gov (United States)

    Kengne, J.; Jafari, S.; Njitacke, Z. T.; Yousefi Azar Khanian, M.; Cheukem, A.

    2017-11-01

    Mathematical models (ODEs) describing the dynamics of almost all continuous time chaotic nonlinear systems (e.g. Lorenz, Rossler, Chua, or Chen system) involve at least a nonlinear term in addition to linear terms. In this contribution, a novel (and singular) 3D autonomous chaotic system without linear terms is introduced. This system has an especial feature of having two twin strange attractors: one ordinary and one symmetric strange attractor when the time is reversed. The complex behavior of the model is investigated in terms of equilibria and stability, bifurcation diagrams, Lyapunov exponent plots, time series and Poincaré sections. Some interesting phenomena are found including for instance, period-doubling bifurcation, antimonotonicity (i.e. the concurrent creation and annihilation of periodic orbits) and chaos while monitoring the system parameters. Compared to the (unique) case previously reported by Xu and Wang (2014) [31], the system considered in this work displays a more 'elegant' mathematical expression and experiences richer dynamical behaviors. A suitable electronic circuit (i.e. the analog simulator) is designed and used for the investigations. Pspice based simulation results show a very good agreement with the theoretical analysis.

  19. Bentall and De Bono surgery for correction of valve and ascending aortic disease: long-term results.

    Science.gov (United States)

    Silva, Virgílio Figueiredo; Real, Daniel Sundfeld Spiga; Branco, João Nelson Rodrigues; Catani, Roberto; Kim, Hyong Chun; Buffolo, Enio; Fonseca, José Honório de Almeida Palma da

    2008-01-01

    A retrospective study was performed in a series of consecutive patients who underwent a Bentall and De Bono procedure. Data were removed of medical records and follow-up data were obtained from clinical records and direct contact with patients. A total of 39 patients were studied between January 1996 and December 2005. The median age was 47 years (range 14-70). There were 33 males and six females. Eleven (25.5%) patients presented Marfan syndrome and one (2.5%) Turner syndrome. Nineteen (48.5%) patients had hypertension, eight (20.5%) had history of smoking, six (15.5%) had history of alcoholism, eight (20.5%) had dyslipidemia, two (5.0%) had diabetes and one (2.56%) had myocardial infarct previously. Twenty-eight (72%) patients were in II-III NYHA class in the moment of the surgery. Annulo-aortic ecstasy was present in 14 (35.9%) patients and aortic aneurysms in 16 (41%). The median time in intensive care unit was 8.79 days with range 2-23 days. Four (10.0%) patients underwent an emergency operation and 35 (90%) elective. The overall hospital mortality was 5% (2/39). The event-free survival is 94.87% at 1 year and 84.61% at in 5 and 10. The median time of follow-up was 46.5 months (range 14-120 months). The Bentall and De Bono technique obtained excellent results in the short-term and long-term, which support the continued use of the compositive graft technique as the preferred method of treatment for patients with aortic root disease. Our findings confirm the current literature data.

  20. DFTBaby: A software package for non-adiabatic molecular dynamics simulations based on long-range corrected tight-binding TD-DFT(B)

    Science.gov (United States)

    Humeniuk, Alexander; Mitrić, Roland

    2017-12-01

    A software package, called DFTBaby, is published, which provides the electronic structure needed for running non-adiabatic molecular dynamics simulations at the level of tight-binding DFT. A long-range correction is incorporated to avoid spurious charge transfer states. Excited state energies, their analytic gradients and scalar non-adiabatic couplings are computed using tight-binding TD-DFT. These quantities are fed into a molecular dynamics code, which integrates Newton's equations of motion for the nuclei together with the electronic Schrödinger equation. Non-adiabatic effects are included by surface hopping. As an example, the program is applied to the optimization of excited states and non-adiabatic dynamics of polyfluorene. The python and Fortran source code is available at http://www.dftbaby.chemie.uni-wuerzburg.de.

  1. Nasal Duplication Combined with Cleft Lip and Palate: Surgical Correction and Long-Term Follow-Up.

    Science.gov (United States)

    Long, Kanharith; Yamaguchi, Kazuaki; Lonic, Daniel; Long, Vanna; Chhoeurn, Vuthy; Lo, Lun-Jou

    2017-10-01

    Diprosopus dirrhinus, or nasal duplication, is a rare entity of partial craniofacial duplication. The case we present is the first report of diprosopus dirrhinus associated with complete cleft lip and palate. The baby was born in Cambodia at full term by normal vaginal delivery with no significant perinatal and family history. Physical examination revealed significant facial deformity due to the duplicated nose and the left complete cleft lip/palate on the right subset. There were 4 nostrils; both medial apertures including the cleft site were found to be 10-15 mm deep cul-de-sac structures without communication to the nasopharynx. The upper third of the face was notable for hypertelorism with a duplication of the soft-tissue nasion and glabella. Between the 2 nasal dorsums, there was a small cutaneous depression with a lacrimal fistula in the midline. Surgical treatment included the first stage of primary lip and nose repair and the second stage of palatoplasty. The patient was followed up at the age of 10 years showing satisfactory results for both aesthetic and functional aspects. Further management in the future will be required for the hypertelorism and nasal deformity.

  2. Correction to: Dynamics of Total Microcystin LR Concentration in Three Subtropical Hydroelectric Generation Reservoirs in Uruguay, South America.

    Science.gov (United States)

    González-Piana, Mauricio; Fabián, Daniel; Piccardo, Andrea; Chalar, Guillermo

    2017-11-01

    The original version of this article contains mistakes. The author inadvertently mentioned units mg/L in all the places of first paragraph under "Results and discussion" section. The correct unit is µg/L. In second paragraph, 10th line under "Results and discussion" section, the value should read as (< 0.05-85.4 µg/mm 3 ) instead of (< 0.05-854.00 µg/mm 3 ). The units and value are corrected through this erratum.

  3. Mechanism for Corrective Action on Budget Imbalances

    Directory of Open Access Journals (Sweden)

    Ion Lucian CATRINA

    2014-02-01

    Full Text Available The European Fiscal Compact sets the obligation for the signatory states to establish an automatic mechanism for taking corrective action on budget imbalances. Nevertheless, the European Treaty says nothing about the tools that should be used in order to reach the desired equilibrium of budgets, but only that it should aim at correcting deviations from the medium-term objective or the adjustment path, including their cumulated impact on government debt dynamics. This paper is aiming at showing that each member state has to build the correction mechanism according to the impact of the chosen tools on economic growth and on general government revenues. We will also emphasize that the correction mechanism should be built not only exacerbating the corrective action through spending/ tax based adjustments, but on a high quality package of economic policies as well.

  4. Tuned resonant mass or inerter-based absorbers: unified calibration with quasi-dynamic flexibility and inertia correction

    DEFF Research Database (Denmark)

    Krenk, Steen; Høgsberg, Jan Becker

    2016-01-01

    effects are included via a flexibility and an inertia coefficient, accounting for the effect of the non-resonant modes. The design procedure starts from a selected level of dynamic amplification and then determines the device parameters for an equivalent dynamic system, in which the background flexibility...

  5. Short-term solar irradiation forecasting based on Dynamic Harmonic Regression

    International Nuclear Information System (INIS)

    Trapero, Juan R.; Kourentzes, Nikolaos; Martin, A.

    2015-01-01

    Solar power generation is a crucial research area for countries that have high dependency on fossil energy sources and is gaining prominence with the current shift to renewable sources of energy. In order to integrate the electricity generated by solar energy into the grid, solar irradiation must be reasonably well forecasted, where deviations of the forecasted value from the actual measured value involve significant costs. The present paper proposes a univariate Dynamic Harmonic Regression model set up in a State Space framework for short-term (1–24 h) solar irradiation forecasting. Time series hourly aggregated as the Global Horizontal Irradiation and the Direct Normal Irradiation will be used to illustrate the proposed approach. This method provides a fast automatic identification and estimation procedure based on the frequency domain. Furthermore, the recursive algorithms applied offer adaptive predictions. The good forecasting performance is illustrated with solar irradiance measurements collected from ground-based weather stations located in Spain. The results show that the Dynamic Harmonic Regression achieves the lowest relative Root Mean Squared Error; about 30% and 47% for the Global and Direct irradiation components, respectively, for a forecast horizon of 24 h ahead. - Highlights: • Solar irradiation forecasts at short-term are required to operate solar power plants. • This paper assesses the Dynamic Harmonic Regression to forecast solar irradiation. • Models are evaluated using hourly GHI and DNI data collected in Spain. • The results show that forecasting accuracy is improved by using the model proposed

  6. Short-term exposure to a synthetic estrogen disrupts mating dynamics in a pipefish.

    Science.gov (United States)

    Partridge, Charlyn; Boettcher, Anne; Jones, Adam G

    2010-11-01

    Sexual selection is responsible for the evolution of some of the most elaborate traits occurring in nature, many of which play a vital role in competition over access to mates and individual reproductive fitness. Because expression of these traits is typically regulated by sex-steroids there is a significant potential for their expression to be affected by the presence of certain pollutants, such as endocrine disrupting compounds. Endocrine disruptors have been shown to alter primary sexual traits and impact reproduction, but few studies have investigated how these compounds affect secondary sexual trait expression and how that may, in turn, impact mating dynamics. In this study we examine how short-term exposure to a synthetic estrogen impacts secondary sexual trait expression and mating dynamics in the Gulf pipefish, a species displaying sex-role reversal. Our results show that only 10days of exposure to 17α-ethinylestradiol results in adult male pipefish developing female-like secondary sexual traits. While these males are capable of reproduction, females discriminate against exposed males in mate choice trials. In natural populations, this type of discrimination would reduce male mating opportunities, thus potentially reducing their long-term reproductive success. Importantly, the effects of these compounds on mating dynamics and mating opportunity would not be observed using the current standard methods of assessing environmental contamination. However, disrupting these processes could have profound effects on the viability of exposed populations. Copyright © 2010 Elsevier Inc. All rights reserved.

  7. Long-term outcome of patients with multiple [corrected] myeloma-related advanced renal failure following auto-SCT.

    Science.gov (United States)

    Glavey, S V; Gertz, M A; Dispenzieri, A; Kumar, S; Buadi, F; Lacy, M; Hayman, S R; Kapoor, P; Dingli, D; McCurdy, A; Hogan, W J; Gastineau, D A; Leung, N

    2013-11-01

    Renal failure commonly complicates multiple myeloma (MM) and is associated with reduced survival. It is not clear whether auto-SCT results in improved renal function or attainment of independence from dialysis in patients with advanced renal impairment due to MM. We conducted a retrospective cohort study of all patients who underwent auto-SCT for MM complicated by advanced renal failure at our institution over a 10-year period (2000-2010). We aimed to assess the association between auto-SCT and renal outcome in patients with serum creatinine (SCr) over 3 mg/dL, attributable to MM, including those who were dialysis dependent. Thirty patients (2.8% of all auto-SCT patients) met inclusion criteria. Fourteen of 15 patients who were dialysis dependent before auto-SCT remained dialysis dependent in the long term despite hematological response (HR). Of the remaining 15 patients with SCr >3 mg/dL, an improvement in glomerular filtration rate (GFR) from 15 to 19.4 mL/min/1.73 m(2) was noted post auto-SCT (P=0.035); however, neither HR post auto-SCT or pre-existing renal function were independently associated with renal outcome. Auto-SCT was not associated with independence from dialysis in patients with renal failure due to MM at our institution. Although auto-SCT was associated with an improvement in GFR in patients with SCr >3 mg/dL, this improvement was not related to HR.

  8. Long-term Follow-up of a Randomized Controlled Trial Comparing Scarf to Chevron Osteotomy in Hallux Valgus Correction.

    Science.gov (United States)

    Jeuken, Ralph M; Schotanus, Martijn G M; Kort, Nanne P; Deenik, Axel; Jong, Bob; Hendrickx, Roel P M

    2016-07-01

    Hallux valgus is one of the most common foot deformities. This long-term follow-up study compared the results of 2 widely used operative treatments for hallux valgus: the scarf and chevron osteotomy. Conventional weight bearing anteroposterior (AP) radiographs of the foot were made for evaluating the intermetatarsal angle and hallux valgus angle. For clinical evaluation, the American Orthopaedic Foot & Ankle Society (AOFAS) rating system for the hallux metatarsophalangeal-interphalangeal scale was used together with physical examination of the foot. These data were compared with the results from the original study. The Short Form 36 questionnaire, the Manchester-Oxford Foot Questionnaire (MOXFQ), and a general questionnaire including a visual analog scale (VAS) pain score were used for subjective evaluation. The primary outcome measures were the radiologic recurrence of hallux valgus and reoperation rate of the same toe. Secondary outcome measures were the results from the radiographs and subjective and clinical evaluation. The response rate was 76% at the follow-up of 14 years; in the chevron group, 37 feet were included compared with 36 feet in the scarf group. Twenty-eight feet in the chevron group and 27 in the scarf group developed recurrence of hallux valgus (P = .483). One patient in the scarf group had a reoperation of the same toe compared with none in the chevron group (P = .314). Current VAS pain scores and results from the SF-36, MOXFQ, and AOFAS did not significantly differ between groups. Both techniques showed similar results after 2 years of follow-up. At 14 years of follow-up, neither technique was superior in preventing recurrence. Level II, randomized controlled trial. © The Author(s) 2016.

  9. Unclassified Source Term and Radionuclide Data for the Groundwater Flow and Contaminant Transport Model of Corrective Action Units 101 and 102: Central and Western Pahute Mesa, Nye County, Nevada, Revision 0

    Energy Technology Data Exchange (ETDEWEB)

    McCord, John

    2004-08-01

    This report documents the evaluation of the information and data available on the unclassified source term and radionuclide contamination for Central and Western Pahute Mesa: Corrective Action Units (CAUs) 101 and 102.

  10. Climate effects and feedback structure determining weed population dynamics in a long-term experiment.

    Science.gov (United States)

    Lima, Mauricio; Navarrete, Luis; González-Andujar, José Luis

    2012-01-01

    Pest control is one of the areas in which population dynamic theory has been successfully applied to solve practical problems. However, the links between population dynamic theory and model construction have been less emphasized in the management and control of weed populations. Most management models of weed population dynamics have emphasized the role of the endogenous process, but the role of exogenous variables such as climate have been ignored in the study of weed populations and their management. Here, we use long-term data (22 years) on two annual weed species from a locality in Central Spain to determine the importance of endogenous and exogenous processes (local and large-scale climate factors). Our modeling study determined two different feedback structures and climate effects in the two weed species analyzed. While Descurainia sophia exhibited a second-order feedback and low climate influence, Veronica hederifolia was characterized by a first-order feedback structure and important effects from temperature and rainfall. Our results strongly suggest the importance of theoretical population dynamics in understanding plant population systems. Moreover, the use of this approach, discerning between the effect of exogenous and endogenous factors, can be fundamental to applying weed management practices in agricultural systems and to controlling invasive weedy species. This is a radical change from most approaches currently used to guide weed and invasive weedy species managements.

  11. Climate Effects and Feedback Structure Determining Weed Population Dynamics in a Long-Term Experiment

    Science.gov (United States)

    Lima, Mauricio; Navarrete, Luis; González-Andujar, José Luis

    2012-01-01

    Pest control is one of the areas in which population dynamic theory has been successfully applied to solve practical problems. However, the links between population dynamic theory and model construction have been less emphasized in the management and control of weed populations. Most management models of weed population dynamics have emphasized the role of the endogenous process, but the role of exogenous variables such as climate have been ignored in the study of weed populations and their management. Here, we use long-term data (22 years) on two annual weed species from a locality in Central Spain to determine the importance of endogenous and exogenous processes (local and large-scale climate factors). Our modeling study determined two different feedback structures and climate effects in the two weed species analyzed. While Descurainia sophia exhibited a second-order feedback and low climate influence, Veronica hederifolia was characterized by a first-order feedback structure and important effects from temperature and rainfall. Our results strongly suggest the importance of theoretical population dynamics in understanding plant population systems. Moreover, the use of this approach, discerning between the effect of exogenous and endogenous factors, can be fundamental to applying weed management practices in agricultural systems and to controlling invasive weedy species. This is a radical change from most approaches currently used to guide weed and invasive weedy species managements. PMID:22272362

  12. Climate effects and feedback structure determining weed population dynamics in a long-term experiment.

    Directory of Open Access Journals (Sweden)

    Mauricio Lima

    Full Text Available Pest control is one of the areas in which population dynamic theory has been successfully applied to solve practical problems. However, the links between population dynamic theory and model construction have been less emphasized in the management and control of weed populations. Most management models of weed population dynamics have emphasized the role of the endogenous process, but the role of exogenous variables such as climate have been ignored in the study of weed populations and their management. Here, we use long-term data (22 years on two annual weed species from a locality in Central Spain to determine the importance of endogenous and exogenous processes (local and large-scale climate factors. Our modeling study determined two different feedback structures and climate effects in the two weed species analyzed. While Descurainia sophia exhibited a second-order feedback and low climate influence, Veronica hederifolia was characterized by a first-order feedback structure and important effects from temperature and rainfall. Our results strongly suggest the importance of theoretical population dynamics in understanding plant population systems. Moreover, the use of this approach, discerning between the effect of exogenous and endogenous factors, can be fundamental to applying weed management practices in agricultural systems and to controlling invasive weedy species. This is a radical change from most approaches currently used to guide weed and invasive weedy species managements.

  13. Long-term competitive dynamics of two cryptic rotifer species: diapause and fluctuating conditions.

    Directory of Open Access Journals (Sweden)

    Carmen Gabaldón

    Full Text Available Life-history traits may have an important role in promoting species coexistence. However, the complexity of certain life cycles makes it difficult to draw conclusions about the conditions for coexistence or exclusion based on the study of short-term competitive dynamics. Brachionus plicatilis and B. manjavacasare two cryptic rotifer species co-occurring in many lakes on the Iberian Peninsula. They have a complex life cycle in which cyclical parthenogenesis occurs with diapausing stages being the result of sexual reproduction. B. plicatilis and B. manjavacasare identical in morphology and size, their biotic niches are broadly overlapping, and they have similar competitive abilities. However, the species differ in life-history traits involving sexual reproduction and diapause, and respond differently to salinity and temperature. As in the case of certain other species that are extremely similar in morphology, a fluctuating environment are considered to be important for their coexistence. We studied the long-term competitive dynamics of B. plicatilis and B. manjavacas under different salinity regimes (constant and fluctuating. Moreover, we focused on the dynamics of the diapausing egg bank to explore how the outcome of the entire life cycle of these rotifers can work to mediate stable coexistence. We demonstrated that these species do not coexist under constant-salinity environment, as the outcome of competition is affected by the level of salinity-at low salinity, B. plicatilis excluded B. manjavacas, and the opposite outcome occurred at high salinity. Competitive dynamics under fluctuating salinity showed that the dominance of one species over the other also tended to fluctuate. The duration of co-occurrence of these species was favoured by salinity fluctuation and perhaps by the existence of a diapausing egg bank. Stable coexistence was not found in our system, which suggests that other factors or other salinity fluctuation patterns might act as

  14. Long-term competitive dynamics of two cryptic rotifer species: diapause and fluctuating conditions.

    Science.gov (United States)

    Gabaldón, Carmen; Carmona, María José; Montero-Pau, Javier; Serra, Manuel

    2015-01-01

    Life-history traits may have an important role in promoting species coexistence. However, the complexity of certain life cycles makes it difficult to draw conclusions about the conditions for coexistence or exclusion based on the study of short-term competitive dynamics. Brachionus plicatilis and B. manjavacasare two cryptic rotifer species co-occurring in many lakes on the Iberian Peninsula. They have a complex life cycle in which cyclical parthenogenesis occurs with diapausing stages being the result of sexual reproduction. B. plicatilis and B. manjavacasare identical in morphology and size, their biotic niches are broadly overlapping, and they have similar competitive abilities. However, the species differ in life-history traits involving sexual reproduction and diapause, and respond differently to salinity and temperature. As in the case of certain other species that are extremely similar in morphology, a fluctuating environment are considered to be important for their coexistence. We studied the long-term competitive dynamics of B. plicatilis and B. manjavacas under different salinity regimes (constant and fluctuating). Moreover, we focused on the dynamics of the diapausing egg bank to explore how the outcome of the entire life cycle of these rotifers can work to mediate stable coexistence. We demonstrated that these species do not coexist under constant-salinity environment, as the outcome of competition is affected by the level of salinity-at low salinity, B. plicatilis excluded B. manjavacas, and the opposite outcome occurred at high salinity. Competitive dynamics under fluctuating salinity showed that the dominance of one species over the other also tended to fluctuate. The duration of co-occurrence of these species was favoured by salinity fluctuation and perhaps by the existence of a diapausing egg bank. Stable coexistence was not found in our system, which suggests that other factors or other salinity fluctuation patterns might act as stabilizing

  15. Rich spectrum of neural field dynamics in the presence of short-term synaptic depression

    Science.gov (United States)

    Wang, He; Lam, Kin; Fung, C. C. Alan; Wong, K. Y. Michael; Wu, Si

    2015-09-01

    In continuous attractor neural networks (CANNs), spatially continuous information such as orientation, head direction, and spatial location is represented by Gaussian-like tuning curves that can be displaced continuously in the space of the preferred stimuli of the neurons. We investigate how short-term synaptic depression (STD) can reshape the intrinsic dynamics of the CANN model and its responses to a single static input. In particular, CANNs with STD can support various complex firing patterns and chaotic behaviors. These chaotic behaviors have the potential to encode various stimuli in the neuronal system.

  16. Simple and reliable procedure for the evaluation of short-term dynamic processes in power systems

    Energy Technology Data Exchange (ETDEWEB)

    Popovic, D P

    1986-10-01

    An efficient approach is presented to the solution of the short-term dynamics model in power systems. It consists of an adequate algebraic treatment of the original system of nonlinear differential equations, using linearization, decomposition and Cauchy's formula. The simple difference equations obtained in this way are incorporated into a model of the electrical network, which is of a low order compared to the ones usually used. Newton's method is applied to the model formed in this way, which leads to a simple and reliable iterative procedure. The characteristics of the procedure developed are demonstrated on examples of transient stability analysis of real power systems. 12 refs.

  17. Deviation from Trajectory Detection in Vision based Robotic Navigation using SURF and Subsequent Restoration by Dynamic Auto Correction Algorithm

    Directory of Open Access Journals (Sweden)

    Ray Debraj

    2015-01-01

    Full Text Available Speeded Up Robust Feature (SURF is used to position a robot with respect to an environment and aid in vision-based robotic navigation. During the course of navigation irregularities in the terrain, especially in an outdoor environment may deviate a robot from the track. Another reason for deviation can be unequal speed of the left and right robot wheels. Hence it is essential to detect such deviations and perform corrective operations to bring the robot back to the track. In this paper we propose a novel algorithm that uses image matching using SURF to detect deviation of a robot from the trajectory and subsequent restoration by corrective operations. This algorithm is executed in parallel to positioning and navigation algorithms by distributing tasks among different CPU cores using Open Multi-Processing (OpenMP API.

  18. SU-E-QI-03: Compartment Modeling of Dynamic Brain PET - The Effect of Scatter and Random Corrections On Parameter Errors

    International Nuclear Information System (INIS)

    Häggström, I; Karlsson, M; Larsson, A; Schmidtlein, C

    2014-01-01

    Purpose: To investigate the effects of corrections for random and scattered coincidences on kinetic parameters in brain tumors, by using ten Monte Carlo (MC) simulated dynamic FLT-PET brain scans. Methods: The GATE MC software was used to simulate ten repetitions of a 1 hour dynamic FLT-PET scan of a voxelized head phantom. The phantom comprised six normal head tissues, plus inserted regions for blood and tumor tissue. Different time-activity-curves (TACs) for all eight tissue types were used in the simulation and were generated in Matlab using a 2-tissue model with preset parameter values (K1,k2,k3,k4,Va,Ki). The PET data was reconstructed into 28 frames by both ordered-subset expectation maximization (OSEM) and 3D filtered back-projection (3DFBP). Five image sets were reconstructed, all with normalization and different additional corrections C (A=attenuation, R=random, S=scatter): Trues (AC), trues+randoms (ARC), trues+scatters (ASC), total counts (ARSC) and total counts (AC). Corrections for randoms and scatters were based on real random and scatter sinograms that were back-projected, blurred and then forward projected and scaled to match the real counts. Weighted non-linearleast- squares fitting of TACs from the blood and tumor regions was used to obtain parameter estimates. Results: The bias was not significantly different for trues (AC), trues+randoms (ARC), trues+scatters (ASC) and total counts (ARSC) for either 3DFBP or OSEM (p<0.05). Total counts with only AC stood out however, with an up to 160% larger bias. In general, there was no difference in bias found between 3DFBP and OSEM, except in parameter Va and Ki. Conclusion: According to our results, the methodology of correcting the PET data for randoms and scatters performed well for the dynamic images where frames have much lower counts compared to static images. Generally, no bias was introduced by the corrections and their importance was emphasized since omitting them increased bias extensively

  19. LONG-TERM MONITORING OF WATER DYNAMICS IN THE SAHEL REGION USING THE MULTI-SAR-SYSTEM

    Directory of Open Access Journals (Sweden)

    A. Bertram

    2016-06-01

    Full Text Available Fresh water is a scarce resource in the West-African Sahel region, seasonally influenced by droughts and floods. Particularly in terms of climate change, the importance of wetlands increases for flora, fauna, human population, agriculture, livestock and fishery. Hence, access to open water is a key factor. Long-term monitoring of water dynamics is of great importance, especially with regard to the spatio-temporal extend of wetlands and drylands. It can predict future trends and facilitate the development of adequate management strategies. Lake Tabalak, a Ramsar wetland of international importance, is one of the most significant ponds in Niger and a refuge for waterbirds. Nevertheless, human population growth increased the pressure on this ecosystem, which is now degrading for all uses. The main objective of the study is a long-term monitoring of the Lake Tabalak’s water dynamics to delineate permanent and seasonal water bodies, using weather- and daytime-independent multi-sensor and multi-temporal Synthetic Aperture Radar (SAR data available for the study area. Data of the following sensors from 1993 until 2016 are used: Sentinel-1A, TerraSARX, ALOS PALSAR-1/2, Envisat ASAR, RADARSAT-1/2, and ERS-1/2. All SAR data are processed with the Multi-SAR-System, unifying the different characteristics of all above mentioned sensors in terms of geometric, radiometric and polarimetric resolution to a consistent format. The polarimetric representation in Kennaugh elements allows fusing single-polarized data acquired by older sensors with multi-polarized data acquired by current sensors. The TANH-normalization guarantees a consistent and therefore comparable description in a closed data range in terms of radiometry. The geometric aspect is solved by projecting all images to an earth-fixed coordinate system correcting the brightness by the help of the incidence angle. The elevation model used in the geocoding step is the novel global model produced by the

  20. Limitless capacity: A dynamic object-oriented approach to short-term memory

    Directory of Open Access Journals (Sweden)

    Bill eMacken

    2015-03-01

    Full Text Available The notion of capacity-limited processing systems is a core element of cognitive accounts of limited and variable performance, enshrined within the short-term memory construct. We begin with a detailed critical analysis of the conceptual bases of this view and argue that there are fundamental problems – ones that go to the heart of cognitivism more generally – that render it untenable. In place of limited capacity systems, we propose a framework for explaining performance that focuses on the dynamic interplay of three aspects of any given setting: the particular task that must be accomplished, the nature and form of the material upon which the task must be performed, and the repertoire of skills and perceptual-motor functions possessed by the participant. We provide empirical examples of the applications of this framework in areas of performance typically accounted for by reference to capacity-limited short-term memory processes.

  1. Limitless capacity: a dynamic object-oriented approach to short-term memory.

    Science.gov (United States)

    Macken, Bill; Taylor, John; Jones, Dylan

    2015-01-01

    The notion of capacity-limited processing systems is a core element of cognitive accounts of limited and variable performance, enshrined within the short-term memory construct. We begin with a detailed critical analysis of the conceptual bases of this view and argue that there are fundamental problems - ones that go to the heart of cognitivism more generally - that render it untenable. In place of limited capacity systems, we propose a framework for explaining performance that focuses on the dynamic interplay of three aspects of any given setting: the particular task that must be accomplished, the nature and form of the material upon which the task must be performed, and the repertoire of skills and perceptual-motor functions possessed by the participant. We provide empirical examples of the applications of this framework in areas of performance typically accounted for by reference to capacity-limited short-term memory processes.

  2. Dynamic visual noise reduces confidence in short-term memory for visual information.

    Science.gov (United States)

    Kemps, Eva; Andrade, Jackie

    2012-05-01

    Previous research has shown effects of the visual interference technique, dynamic visual noise (DVN), on visual imagery, but not on visual short-term memory, unless retention of precise visual detail is required. This study tested the prediction that DVN does also affect retention of gross visual information, specifically by reducing confidence. Participants performed a matrix pattern memory task with three retention interval interference conditions (DVN, static visual noise and no interference control) that varied from trial to trial. At recall, participants indicated whether or not they were sure of their responses. As in previous research, DVN did not impair recall accuracy or latency on the task, but it did reduce recall confidence relative to static visual noise and no interference. We conclude that DVN does distort visual representations in short-term memory, but standard coarse-grained recall measures are insensitive to these distortions.

  3. Can the dynamics of the term structure of petroleum futures be forecasted? Evidence from major markets

    International Nuclear Information System (INIS)

    Skiadopoulos, George; Chantziara, Thalia

    2008-01-01

    We investigate whether the daily evolution of the term structure of petroleum futures can be forecasted. To this end, the principal components analysis is employed. The retained principal components describe the dynamics of the term structure of futures prices parsimoniously and are used to forecast the subsequent daily changes of futures prices. Data on the New York Mercantile Exchange (NYMEX) crude oil, heating oil, gasoline, and the International Petroleum Exchange (IPE) crude oil futures are used. We find that the retained principal components have small forecasting power both in-sample and out-of-sample. Similar results are obtained from standard univariate and vector autoregression models. Spillover effects between the four petroleum futures markets are also detected. (author)

  4. Sci-Fri AM: Imaging - 09: Serial estimation of cross-talk for correction in dual-isotope imaging with dynamic tracers.

    Science.gov (United States)

    Wells, R G; Lockwood, J; Wei, L; Duan, D; Fernando, P; Bensimon, C; Ruddy, T D

    2012-07-01

    The recent radioisotope shortage has led to interest in non-Tc99m-based tracers. We have developed a novel I-123-labelled myocardial perfusion imaging tracer. We compare the I123-tracer to the clinical standard of Tc99m tetrofosmin in vivo in a rat model using a small-animal SPECT/CT camera. SPECT distinguishes different isotopes based on the different energies of the emitted gamma rays and thus allows simultaneous comparison of two tracer distributions in the same animal. Dual-isotope imaging is complicated by cross-talk between the energy windows of the isotopes. Standard energy-window-based correction methods are difficult to employ because of the proximity in energy of Tc99m (140keV) and I123 (159keV). Imaging the second tracer's energy window prior to its injection provides an estimate of the cross-talk. However, this estimate is only accurate if the tracer distribution is static. We use serial imaging prior to the introduction of the second tracer to estimate the dynamics of the first tracer and interpolate the cross-talk images to provide a more accurate correction. We used rat models of myocardial disease (n=3). I123 tracer was injected and imaged for one hour at 20min intervals. The Tc99m tetrofosmin was then injected and 30min later, a dual-isotope image was obtained. The impact of this approach is assessed by comparing the differences in the Tc99m-tetrofosmin image using this method with correction by simple correction for physical decay. The interpolative approach improves the accuracy of the correction by 2%-5% and thereby enhances the comparison of the two tracers. © 2012 American Association of Physicists in Medicine.

  5. Cryopreservation of testicular tissue before long-term testicular cell culture does not alter in vitro cell dynamics

    NARCIS (Netherlands)

    Baert, Yoni; Braye, Aude; Struijk, Robin B.; van Pelt, Ans M. M.; Goossens, Ellen

    2015-01-01

    To assess whether testicular cell dynamics are altered during long-term culture after testicular tissue cryopreservation. Experimental basic science study. Reproductive biology laboratory. Testicular tissue with normal spermatogenesis was obtained from six donors. None. Detection and comparison of

  6. Electroweak corrections

    International Nuclear Information System (INIS)

    Beenakker, W.J.P.

    1989-01-01

    The prospect of high accuracy measurements investigating the weak interactions, which are expected to take place at the electron-positron storage ring LEP at CERN and the linear collider SCL at SLAC, offers the possibility to study also the weak quantum effects. In order to distinguish if the measured weak quantum effects lie within the margins set by the standard model and those bearing traces of new physics one had to go beyond the lowest order and also include electroweak radiative corrections (EWRC) in theoretical calculations. These higher-order corrections also can offer the possibility of getting information about two particles present in the Glashow-Salam-Weinberg model (GSW), but not discovered up till now, the top quark and the Higgs boson. In ch. 2 the GSW standard model of electroweak interactions is described. In ch. 3 some special techniques are described for determination of integrals which are responsible for numerical instabilities caused by large canceling terms encountered in the calculation of EWRC effects, and methods necessary to get hold of the extensive algebra typical for EWRC. In ch. 4 various aspects related to EWRC effects are discussed, in particular the dependence of the unknown model parameters which are the masses of the top quark and the Higgs boson. The processes which are discussed are production of heavy fermions from electron-positron annihilation and those of the fermionic decay of the Z gauge boson. (H.W.). 106 refs.; 30 figs.; 6 tabs.; schemes

  7. Computer simulation of yielding supports under static and short-term dynamic load

    Directory of Open Access Journals (Sweden)

    Kumpyak Oleg

    2018-01-01

    Full Text Available Dynamic impacts that became frequent lately cause large human and economic losses, and their prevention methods are not always effective and reasonable. The given research aims at studying the way of enhancing explosion safety of building structures by means of yielding supports. The paper presents results of numerical studies of strength and deformation property of yielding supports in the shape of annular tubes under static and short-term dynamic loading. The degree of influence of yielding supports was assessed taking into account three peculiar stages of deformation: elastic; elasto-plastic; and elasto-plastic with hardening. The methodology for numerical studies performance was described using finite element analysis with program software Ansys Mechanical v17.2. It was established that rigidity of yielding supports influences significantly their stress-strain state. The research determined that with the increase in deformable elements rigidity dependence between load and deformation of the support in elastic and plastic stages have linear character. Significant reduction of the dynamic response and increase in deformation time of yielding supports were observed due to increasing the plastic component. Therefore, it allows assuming on possibility of their application as supporting units in RC beams.

  8. Dynamical prediction and pattern mapping in short-term load forecasting

    Energy Technology Data Exchange (ETDEWEB)

    Aguirre, Luis Antonio; Rodrigues, Daniela D.; Lima, Silvio T. [Departamento de Engenharia Eletronica, Universidade Federal de Minas Gerais, Av. Antonio Carlos, 6627, 31270-901 Belo Horizonte, MG (Brazil); Martinez, Carlos Barreira [Departamento de Engenharia Hidraulica e Recursos Hidricos, Universidade Federal de Minas Gerais, Av. Antonio Carlos, 6627, 31270-901 Belo Horizonte, MG (Brazil)

    2008-01-15

    This work will not put forward yet another scheme for short-term load forecasting but rather will provide evidences that may improve our understanding about fundamental issues which underlay load forecasting problems. In particular, load forecasting will be decomposed into two main problems, namely dynamical prediction and pattern mapping. It is argued that whereas the latter is essentially static and becomes nonlinear when weekly features in the data are taken into account, the former might not be deterministic at all. In such cases there is no determinism (serial correlations) in the data apart from the average cycle and the best a model can do is to perform pattern mapping. Moreover, when there is determinism in addition to the average cycle, the underlying dynamics are sometimes linear, in which case there is no need to resort to nonlinear models to perform dynamical prediction. Such conclusions were confirmed using real load data and surrogate data analysis. In a sense, the paper details and organizes some general beliefs found in the literature on load forecasting. This sheds some light on real model-building and forecasting problems and helps understand some apparently conflicting results reported in the literature. (author)

  9. Long-term influence of asteroids on planet longitudes and chaotic dynamics of the solar system

    Science.gov (United States)

    Woillez, E.; Bouchet, F.

    2017-11-01

    Over timescales much longer than an orbital period, the solar system exhibits large-scale chaotic behavior and can thus be viewed as a stochastic dynamical system. The aim of the present paper is to compare different sources of stochasticity in the solar system. More precisely we studied the importance of the long term influence of asteroids on the chaotic dynamics of the solar system. We show that the effects of asteroids on planets is similar to a white noise process, when those effects are considered on a timescale much larger than the correlation time τϕ ≃ 104 yr of asteroid trajectories. We computed the timescale τe after which the effects of the stochastic evolution of the asteroids lead to a loss of information for the initial conditions of the perturbed Laplace-Lagrange secular dynamics. The order of magnitude of this timescale is precisely determined by theoretical argument, and we find that τe ≃ 104 Myr. Although comparable to the full main-sequence lifetime of the sun, this timescale is considerably longer than the Lyapunov time τI ≃ 10 Myr of the solar system without asteroids. This shows that the external sources of chaos arise as a small perturbation in the stochastic secular behavior of the solar system, rather due to intrinsic chaos.

  10. Long-term Seedling Dynamics of Tree Species in a Subtropical Rain Forest, Taiwan

    Directory of Open Access Journals (Sweden)

    Chia-Hao Chang-Yang

    2013-03-01

    Full Text Available Knowledge of demographical rates at seedling stage is critical for understanding forest composition and dynamics. We monitored the seedling dynamics of tree species in a subtropical rain forest in Fushan, northern Taiwan (24°45’ N, 121°35’ E during an 8-yr period (2003–2010. There were great temporal fluctuations in the seedling density, which might be largely driven by the pulses of seedling recruitment. Interspecific variation in the seedling abundance, however, was not related to the reproductive adult abundance. Previous studies showed that frequent typhoon disturbances contributed to the high canopy openness and high understory light availability at Fushan, which might benefit tree regeneration. But our results do not support this idea. Most of the newly recruited seedlings died within six months and only grew 1.55 ± 0.20 cm per year, which might be suppressed by the dense understory vegetation. Our results suggested that the majority of tree species in Fushan were recruitment limited, which might have important consequences for species coexistence. High temporal variability in recruitment density and low growth rates of seedlings emphasize the importance of long-term studies to our understandings of forest dynamics.

  11. Short-term wavelike dynamics of bacterial populations in response to nutrient input from fresh plant residues

    NARCIS (Netherlands)

    Zelenev, V.V.; Bruggen, van A.H.C.; Semenov, A.M.

    2005-01-01

    The objectives of the research were to investigate short-term dynamics of bacterial populations in soil after a disturbance in the form of fresh organic matter incorporation and to investigate how these dynamics are linked to those of some environmental parameters. To reach these objectives, soil

  12. Dynamic correction of the laser beam coordinate in fabrication of large-sized diffractive elements for testing aspherical mirrors

    Science.gov (United States)

    Shimansky, R. V.; Poleshchuk, A. G.; Korolkov, V. P.; Cherkashin, V. V.

    2017-05-01

    This paper presents a method of improving the accuracy of a circular laser system in fabrication of large-diameter diffractive optical elements by means of a polar coordinate system and the results of their use. An algorithm for correcting positioning errors of a circular laser writing system developed at the Institute of Automation and Electrometry, SB RAS, is proposed and tested. Highprecision synthesized holograms fabricated by this method and the results of using these elements for testing the 6.5 m diameter aspheric mirror of the James Webb space telescope (JWST) are described..

  13. [Posttraumatic disturbances in patients with light craniocerebral injury and their correction via various variants of dynamic magnetotherapy].

    Science.gov (United States)

    Cherevashchenko, L A; Moliavchikova, O V; Zhuravlev, M E

    2008-01-01

    Examination of 90 patients in intermediate period of slight craniocerebral injury before and after use of curative technologies with including of dynamic magnetotherapy suboccipitally or transcranially. It is established, that choosing rehabilitation methods, it is necessary to take into consideration clinical manifestation of disease, state of cerebral blood circulation, vegetative nervous system, bioelectrogenesis of cerebrum.

  14. Short- and long-term evolutionary dynamics of bacterial insertion sequences: insights from Wolbachia endosymbionts.

    Science.gov (United States)

    Cerveau, Nicolas; Leclercq, Sébastien; Leroy, Elodie; Bouchon, Didier; Cordaux, Richard

    2011-01-01

    Transposable elements (TE) are one of the major driving forces of genome evolution, raising the question of the long-term dynamics underlying their evolutionary success. Long-term TE evolution can readily be reconstructed in eukaryotes, thanks to many degraded copies constituting genomic fossil records of past TE proliferations. By contrast, bacterial genomes usually experience high sequence turnover and short TE retention times, thereby obscuring ancient TE evolutionary patterns. We found that Wolbachia bacterial genomes contain 52-171 insertion sequence (IS) TEs. IS account for 11% of Wolbachia wRi, which is one of the highest IS genomic coverage reported in prokaryotes to date. We show that many IS groups are currently expanding in various Wolbachia genomes and that IS horizontal transfers are frequent among strains, which can explain the apparent synchronicity of these IS proliferations. Remarkably, >70% of Wolbachia IS are nonfunctional. They constitute an unusual bacterial IS genomic fossil record providing direct empirical evidence for a long-term IS evolutionary dynamics following successive periods of intense transpositional activity. Our results show that comprehensive IS annotations have the potential to provide new insights into prokaryote TE evolution and, more generally, prokaryote genome evolution. Indeed, the identification of an important IS genomic fossil record in Wolbachia demonstrates that IS elements are not always of recent origin, contrary to the conventional view of TE evolution in prokaryote genomes. Our results also raise the question whether the abundance of IS fossils is specific to Wolbachia or it may be a general, albeit overlooked, feature of prokaryote genomes.

  15. Do leukocyte telomere length dynamics depend on baseline telomere length? An analysis that corrects for ‘regression to the mean’

    International Nuclear Information System (INIS)

    Verhulst, Simon; Aviv, Abraham; Benetos, Athanase; Berenson, Gerald S.; Kark, Jeremy D.

    2013-01-01

    Leukocyte telomere length (LTL) shortens with age. Longitudinal studies have reported accelerated LTL attrition when baseline LTL is longer. However, the dependency of LTL attrition on baseline LTL might stem from a statistical artifact known as regression to the mean (RTM). To our knowledge no published study of LTL dynamics (LTL and its attrition rate) has corrected for this phenomenon. We illustrate the RTM effect using replicate LTL measurements, and show, using simulated data, how the RTM effect increases with a rise in stochastic measurement variation (representing LTL measurement error), resulting in spurious increasingly elevated dependencies of attrition on baseline values. In addition, we re-analyzed longitudinal LTL data collected from four study populations to test the hypothesis that LTL attrition depends on baseline LTL. We observed that the rate of LTL attrition was proportional to baseline LTL, but correction for the RTM effect reduced the slope of the relationship by 57 % when measurement error was low (coefficient of variation ∼2 %). A modest but statistically significant effect remained however, indicating that high baseline LTL is associated with higher LTL attrition even when correcting for the RTM effect. Baseline LTL explained 1.3 % of the variation in LTL attrition, but this effect, which differed significantly between the study samples, appeared to be primarily attributable to the association in men (3.7 %)

  16. Wavefront correction for static and dynamic aberrations to within 1 second of the system shot in the NIF Beamlet demonstration facility

    International Nuclear Information System (INIS)

    Hartley, R.; Kartz, M.; Behrendt, W.

    1996-10-01

    The laser wavefront of the NIF Beamlet demonstration system is corrected for static aberrations with a wavefront control system. The system operates closed loop with a probe beam prior to a shot and has a loop bandwidth of about 3 Hz. However, until recently the wavefront control system was disabled several minutes prior to the shot to allow time to manually reconfigure its attenuators and probe beam insertion mechanism to shot mode. Thermally-induced dynamic variations in gas density in the Beamlet main beam line produce significant wavefront error. After about 5-8 seconds, the wavefront error has increased to a new, higher level due to turbulence- induced aberrations no longer being corrected- This implies that there is a turbulence-induced aberration noise bandwidth of less than one Hertz, and that the wavefront controller could correct for the majority of turbulence-induced aberration (about one- third wave) by automating its reconfiguration to occur within one second of the shot, This modification was recently implemented on Beamlet; we call this modification the t 0 -1 system

  17. Constraints on Dynamic Triggering from very Short term Microearthquake Aftershocks at Parkfield

    Science.gov (United States)

    Ampuero, J.; Rubin, A.

    2004-12-01

    The study of microearthquakes helps bridge the gap between laboratory experiments and data from large earthquakes, the two disparate scales that have contributed so far to our understanding of earthquake physics. Although they are frequent, microearthquakes are difficult to analyse. Applying high precision relocation techniques, Rubin and Gillard (2000) observed a pronounced asymmetry in the spatial distribution of the earliest and nearest aftershocks of microearthquakes along the San Andreas fault (they occur more often to the NW of the mainshock). It was suggested that this could be related to the velocity contrast across the fault. Preferred directivity of dynamic rupture pulses running along a bimaterial interface (to the SE in the case of the SAF) is expected on theoretical grounds. Our numerical simulations of crack-like rupture on such interfaces show a pronounced asymmetry of the stress histories beyond the rupture ends, and suggest two possible mechanisms for the observed asymmetry: First, that it results from an asymmmetry in the static stress field following arrest of the mainshock (closer to failure to the NW), or second, that it is due to a short-duration tensile pulse that propagates to the SE, which could reduce the number of aftershocks to the SE by dynamic triggering of any nucleation site close enough to failure to have otherwise produced an aftershock. To distinguish betwen these mechanisms we need observations of dynamic triggering in microseismicity. For small events triggered at a distance of some mainshock radii, triggering time scales are so short that seismograms of both events overlap. To detect the occurrence of compound events and very short term aftershocks in the HRSN Parkfield archived waveforms we have developed an automated search algorithm based on empirical Green's function (EGF) deconvolution. Optimal EGFs are first selected by the coherency of the cross-component convolution with respect to the target event. Then Landweber

  18. STUDY OF UNCONVENTIONAL TEXTILES USED AS INSERTION FOR CLOTHES IN TERMS OF ITS DYNAMIC TENSILE STREGHT

    Directory of Open Access Journals (Sweden)

    OANA Dorina

    2015-05-01

    Full Text Available Unconventional textiles are manufactured different from those obtained by the classic spinning weaving and knitting. They are obtained by mechanical or chemical consolidation of a textile backing up of fibrous layers or combinations of layers of fiber and yarn, fabrics and yarns, fabrics or knitted fabrics and fibers. For the apparel industry has expanded the use of unconventional fabrics especially in auxiliary materials they replace traditional materials such as woven tassel and buckram. Application of reinforcement layers have very important role in increasing the stability of form and material exploitation basic characteristics. Using unconventional fabrics used as insertions for clothing presents a desosibit advantage in terms of possible replacement joints bonded by heat sealed seam, thus saving time and using technology more accessible. For unconventional fabrics used as auxiliaries in the apparel industry is usually determined flexural stiffness, tensile strength, resistance to repeated stretches but more efficient in terms of proximity to the real conditions of the clothing is dynamic tensile resistance. Unconventional textile materials have a certain anisotropy in terms of the performed measurements. So, we followed the conducted research to highlight the anisotropy of several samples and characterization of best of unconventional materials in this regard, to be used under conditions effective as clothing industry.

  19. Surgical correction of Peyronie's disease via tunica albuginea plication or partial plaque excision with pericardial graft: long-term follow up.

    Science.gov (United States)

    Taylor, Frederick L; Levine, Laurence A

    2008-09-01

    Limited publications exist regarding long-term outcomes of surgical correction for Peyronie's Disease (PD). To report on long-term postoperative parameters including rigidity, curvature, length, sensation, function, and patient satisfaction in men with PD treated surgically via Tunica Albuginea Plication (TAP) or Partial Plaque Excision with Tutoplast Human Pericardial Grafting (PEG). Objective and subjective data regarding patients who underwent either TAP or PEG. We report on 142 patients (61 TAP and 81 PEG) with both objective data and subjective patient reports on their postoperative experience. Patients underwent either TAP or PEG following our previously published algorithm. Data was collected via chart review and an internally generated survey, in which patients were asked about their rigidity, straightness, penile length, sensation, sexual function and satisfaction. Average follow up for TAP patients was 72 months (range 8-147) and 58 months (range 6-185) for PEG patients. At survey time, 93% of TAP and 91% of PEG patients reported curvatures of less than 30o. Rigidity was reportedly as good as or better than preoperative in 81% of TAP and 68% of PEG patients, and was adequate for coitus in 90% of TAP and 79% of PEG patients with or without the use of PDE5i. Objective flaccid stretched penile length measurements obtained pre and postoperatively show an average overall length gain of 0.6 cm (range -3.5-3.5) for TAP and 0.2 cm (range -1.5-2.0) for PEG patients. Sensation was reportedly as good as or better than preoperative in 69% of both TAP and PEG patients; 98% of TAP patients and 90% of PEG are able to achieve orgasm. 82% of TAP patients and 75% of PEG patients were either very satisfied or satisfied. Our long-term results support both TAP and PEG as durable surgical therapy for men with clinically significant PD.

  20. Understanding the many-body expansion for large systems. III. Critical role of four-body terms, counterpoise corrections, and cutoffs.

    Science.gov (United States)

    Liu, Kuan-Yu; Herbert, John M

    2017-10-28

    Papers I and II in this series [R. M. Richard et al., J. Chem. Phys. 141, 014108 (2014); K. U. Lao et al., ibid. 144, 164105 (2016)] have attempted to shed light on precision and accuracy issues affecting the many-body expansion (MBE), which only manifest in larger systems and thus have received scant attention in the literature. Many-body counterpoise (CP) corrections are shown to accelerate convergence of the MBE, which otherwise suffers from a mismatch between how basis-set superposition error affects subsystem versus supersystem calculations. In water clusters ranging in size up to (H 2 O) 37 , four-body terms prove necessary to achieve accurate results for both total interaction energies and relative isomer energies, but the sheer number of tetramers makes the use of cutoff schemes essential. To predict relative energies of (H 2 O) 20 isomers, two approximations based on a lower level of theory are introduced and an ONIOM-type procedure is found to be very well converged with respect to the appropriate MBE benchmark, namely, a CP-corrected supersystem calculation at the same level of theory. Results using an energy-based cutoff scheme suggest that if reasonable approximations to the subsystem energies are available (based on classical multipoles, say), then the number of requisite subsystem calculations can be reduced even more dramatically than when distance-based thresholds are employed. The end result is several accurate four-body methods that do not require charge embedding, and which are stable in large basis sets such as aug-cc-pVTZ that have sometimes proven problematic for fragment-based quantum chemistry methods. Even with aggressive thresholding, however, the four-body approach at the self-consistent field level still requires roughly ten times more processors to outmatch the performance of the corresponding supersystem calculation, in test cases involving 1500-1800 basis functions.

  1. Understanding the many-body expansion for large systems. III. Critical role of four-body terms, counterpoise corrections, and cutoffs

    Science.gov (United States)

    Liu, Kuan-Yu; Herbert, John M.

    2017-10-01

    Papers I and II in this series [R. M. Richard et al., J. Chem. Phys. 141, 014108 (2014); K. U. Lao et al., ibid. 144, 164105 (2016)] have attempted to shed light on precision and accuracy issues affecting the many-body expansion (MBE), which only manifest in larger systems and thus have received scant attention in the literature. Many-body counterpoise (CP) corrections are shown to accelerate convergence of the MBE, which otherwise suffers from a mismatch between how basis-set superposition error affects subsystem versus supersystem calculations. In water clusters ranging in size up to (H2O)37, four-body terms prove necessary to achieve accurate results for both total interaction energies and relative isomer energies, but the sheer number of tetramers makes the use of cutoff schemes essential. To predict relative energies of (H2O)20 isomers, two approximations based on a lower level of theory are introduced and an ONIOM-type procedure is found to be very well converged with respect to the appropriate MBE benchmark, namely, a CP-corrected supersystem calculation at the same level of theory. Results using an energy-based cutoff scheme suggest that if reasonable approximations to the subsystem energies are available (based on classical multipoles, say), then the number of requisite subsystem calculations can be reduced even more dramatically than when distance-based thresholds are employed. The end result is several accurate four-body methods that do not require charge embedding, and which are stable in large basis sets such as aug-cc-pVTZ that have sometimes proven problematic for fragment-based quantum chemistry methods. Even with aggressive thresholding, however, the four-body approach at the self-consistent field level still requires roughly ten times more processors to outmatch the performance of the corresponding supersystem calculation, in test cases involving 1500-1800 basis functions.

  2. A novel method for calculating the dynamic capillary force and correcting the pressure error in micro-tube experiment.

    Science.gov (United States)

    Wang, Shuoliang; Liu, Pengcheng; Zhao, Hui; Zhang, Yuan

    2017-11-29

    Micro-tube experiment has been implemented to understand the mechanisms of governing microcosmic fluid percolation and is extensively used in both fields of micro electromechanical engineering and petroleum engineering. The measured pressure difference across the microtube is not equal to the actual pressure difference across the microtube. Taking into account the additional pressure losses between the outlet of the micro tube and the outlet of the entire setup, we propose a new method for predicting the dynamic capillary pressure using the Level-set method. We first demonstrate it is a reliable method for describing microscopic flow by comparing the micro-model flow-test results against the predicted results using the Level-set method. In the proposed approach, Level-set method is applied to predict the pressure distribution along the microtube when the fluids flow along the microtube at a given flow rate; the microtube used in the calculation has the same size as the one used in the experiment. From the simulation results, the pressure difference across a curved interface (i.e., dynamic capillary pressure) can be directly obtained. We also show that dynamic capillary force should be properly evaluated in the micro-tube experiment in order to obtain the actual pressure difference across the microtube.

  3. Dynamics of Hippocampal Protein Expression During Long-term Spatial Memory Formation*

    Science.gov (United States)

    Borovok, Natalia; Nesher, Elimelech; Levin, Yishai; Reichenstein, Michal; Pinhasov, Albert

    2016-01-01

    Spatial memory depends on the hippocampus, which is particularly vulnerable to aging. This vulnerability has implications for the impairment of navigation capacities in older people, who may show a marked drop in performance of spatial tasks with advancing age. Contemporary understanding of long-term memory formation relies on molecular mechanisms underlying long-term synaptic plasticity. With memory acquisition, activity-dependent changes occurring in synapses initiate multiple signal transduction pathways enhancing protein turnover. This enhancement facilitates de novo synthesis of plasticity related proteins, crucial factors for establishing persistent long-term synaptic plasticity and forming memory engrams. Extensive studies have been performed to elucidate molecular mechanisms of memory traces formation; however, the identity of plasticity related proteins is still evasive. In this study, we investigated protein turnover in mouse hippocampus during long-term spatial memory formation using the reference memory version of radial arm maze (RAM) paradigm. We identified 1592 proteins, which exhibited a complex picture of expression changes during spatial memory formation. Variable linear decomposition reduced significantly data dimensionality and enriched three principal factors responsible for variance of memory-related protein levels at (1) the initial phase of memory acquisition (165 proteins), (2) during the steep learning improvement (148 proteins), and (3) the final phase of the learning curve (123 proteins). Gene ontology and signaling pathways analysis revealed a clear correlation between memory improvement and learning phase-curbed expression profiles of proteins belonging to specific functional categories. We found differential enrichment of (1) neurotrophic factors signaling pathways, proteins regulating synaptic transmission, and actin microfilament during the first day of the learning curve; (2) transcription and translation machinery, protein

  4. Dynamics of Hippocampal Protein Expression During Long-term Spatial Memory Formation.

    Science.gov (United States)

    Borovok, Natalia; Nesher, Elimelech; Levin, Yishai; Reichenstein, Michal; Pinhasov, Albert; Michaelevski, Izhak

    2016-02-01

    Spatial memory depends on the hippocampus, which is particularly vulnerable to aging. This vulnerability has implications for the impairment of navigation capacities in older people, who may show a marked drop in performance of spatial tasks with advancing age. Contemporary understanding of long-term memory formation relies on molecular mechanisms underlying long-term synaptic plasticity. With memory acquisition, activity-dependent changes occurring in synapses initiate multiple signal transduction pathways enhancing protein turnover. This enhancement facilitates de novo synthesis of plasticity related proteins, crucial factors for establishing persistent long-term synaptic plasticity and forming memory engrams. Extensive studies have been performed to elucidate molecular mechanisms of memory traces formation; however, the identity of plasticity related proteins is still evasive. In this study, we investigated protein turnover in mouse hippocampus during long-term spatial memory formation using the reference memory version of radial arm maze (RAM) paradigm. We identified 1592 proteins, which exhibited a complex picture of expression changes during spatial memory formation. Variable linear decomposition reduced significantly data dimensionality and enriched three principal factors responsible for variance of memory-related protein levels at (1) the initial phase of memory acquisition (165 proteins), (2) during the steep learning improvement (148 proteins), and (3) the final phase of the learning curve (123 proteins). Gene ontology and signaling pathways analysis revealed a clear correlation between memory improvement and learning phase-curbed expression profiles of proteins belonging to specific functional categories. We found differential enrichment of (1) neurotrophic factors signaling pathways, proteins regulating synaptic transmission, and actin microfilament during the first day of the learning curve; (2) transcription and translation machinery, protein

  5. Factors in Outcomes of Short-Term Dynamic Psychotherapy for Chronic vs. Nonchronic Major Depression

    Science.gov (United States)

    LUBORSKY, LESTER; DIGUER, LOUIS; CACCIOLA, JOHN; BARBER, JACQUES P.; MORAS, KARLA; SCHMIDT, KELLY; DERUBEIS, ROBERT J.

    1996-01-01

    The benefits, and variables influencing the benefits, of short-term dynamic psychotherapy for chronic major depression versus nonchronic major depression were examined for 49 patients. The two diagnostic groups started at the same level on the Beck Depression Inventory (BDI) and Global Assessment of Functioning Scale (GAF) and benefited similarly. The bases for the benefits were examined by linear models explaining 35% of termination BDI variance and 47% of termination GAF scores. By far the largest contributor to outcome was initial GAF, followed by presence of more than one comorbid Axis I diagnosis. Initial level of depression on the BDI was not a significant predictor of termination BDI. The chronic/ nonchronic distinction accounted for less than 1% of explained variance, and little was added by personality disorder, age, or gender. PMID:22700274

  6. Long-term WWER-440 dynamics in cyclic power output changes

    International Nuclear Information System (INIS)

    Petruzela, I.

    1989-01-01

    Xenon poisoning is one of the main factors limiting the operation of a nuclear power plant with a WWER-440 reactor in the variable load mode, when long-term dynamics applies to cyclic power output changes. An analysis of the xenon poisoning linearized transfer shows that a phase shift of 180deg takes place between the summed-up reactivity change due to a power change and the reactivity change due to xenon poisoning, this for a sine-wave power change with a period of 24 hours. Thus, the requirements are minimized for the change in reactivity of the control elements, and the maximum value can be achieved of released reactivity that can be utilized before the end of the campaign. (B.S.). 6 figs., 4 tabs., 9 refs

  7. Equipartition terms in transition path ensemble: Insights from molecular dynamics simulations of alanine dipeptide

    Science.gov (United States)

    Li, Wenjin

    2018-02-01

    Transition path ensemble consists of reactive trajectories and possesses all the information necessary for the understanding of the mechanism and dynamics of important condensed phase processes. However, quantitative description of the properties of the transition path ensemble is far from being established. Here, with numerical calculations on a model system, the equipartition terms defined in thermal equilibrium were for the first time estimated in the transition path ensemble. It was not surprising to observe that the energy was not equally distributed among all the coordinates. However, the energies distributed on a pair of conjugated coordinates remained equal. Higher energies were observed to be distributed on several coordinates, which are highly coupled to the reaction coordinate, while the rest were almost equally distributed. In addition, the ensemble-averaged energy on each coordinate as a function of time was also quantified. These quantitative analyses on energy distributions provided new insights into the transition path ensemble.

  8. Long-term stable time integration scheme for dynamic analysis of planar geometrically exact Timoshenko beams

    Science.gov (United States)

    Nguyen, Tien Long; Sansour, Carlo; Hjiaj, Mohammed

    2017-05-01

    In this paper, an energy-momentum method for geometrically exact Timoshenko-type beam is proposed. The classical time integration schemes in dynamics are known to exhibit instability in the non-linear regime. The so-called Timoshenko-type beam with the use of rotational degree of freedom leads to simpler strain relations and simpler expressions of the inertial terms as compared to the well known Bernoulli-type model. The treatment of the Bernoulli-model has been recently addressed by the authors. In this present work, we extend our approach of using the strain rates to define the strain fields to in-plane geometrically exact Timoshenko-type beams. The large rotational degrees of freedom are exactly computed. The well-known enhanced strain method is used to avoid locking phenomena. Conservation of energy, momentum and angular momentum is proved formally and numerically. The excellent performance of the formulation will be demonstrated through a range of examples.

  9. Long-term and seasonal dynamics of dengue in Iquitos, Peru.

    Directory of Open Access Journals (Sweden)

    Steven T Stoddard

    2014-07-01

    Full Text Available Long-term disease surveillance data provide a basis for studying drivers of pathogen transmission dynamics. Dengue is a mosquito-borne disease caused by four distinct, but related, viruses (DENV-1-4 that potentially affect over half the world's population. Dengue incidence varies seasonally and on longer time scales, presumably driven by the interaction of climate and host susceptibility. Precise understanding of dengue dynamics is constrained, however, by the relative paucity of laboratory-confirmed longitudinal data.We studied 10 years (2000-2010 of laboratory-confirmed, clinic-based surveillance data collected in Iquitos, Peru. We characterized inter and intra-annual patterns of dengue dynamics on a weekly time scale using wavelet analysis. We explored the relationships of case counts to climatic variables with cross-correlation maps on annual and trimester bases.Transmission was dominated by single serotypes, first DENV-3 (2001-2007 then DENV-4 (2008-2010. After 2003, incidence fluctuated inter-annually with outbreaks usually occurring between October and April. We detected a strong positive autocorrelation in case counts at a lag of ∼ 70 weeks, indicating a shift in the timing of peak incidence year-to-year. All climatic variables showed modest seasonality and correlated weakly with the number of reported dengue cases across a range of time lags. Cases were reduced after citywide insecticide fumigation if conducted early in the transmission season.Dengue case counts peaked seasonally despite limited intra-annual variation in climate conditions. Contrary to expectations for this mosquito-borne disease, no climatic variable considered exhibited a strong relationship with transmission. Vector control operations did, however, appear to have a significant impact on transmission some years. Our results indicate that a complicated interplay of factors underlie DENV transmission in contexts such as Iquitos.

  10. A wearable wireless ECG monitoring system with dynamic transmission power control for long-term homecare.

    Science.gov (United States)

    Wang, Yishan; Doleschel, Sammy; Wunderlich, Ralf; Heinen, Stefan

    2015-03-01

    This paper presents a wearable wireless ECG monitoring system based on novel 3-Lead electrode placements for long-term homecare. The experiment for novel 3-Lead electrode placements is carried out, and the results show that the distance between limb electrodes can be significantly reduced. Based on the new electrode position, a small size sensor node, which is powered by a rechargeable battery, is designed to detect, amplify, filter and transmit the ECG signals. The coordinator receives the data and sends it to PC. Finally the signals are displayed on the GUI. In order to control the power consumption of sensor node, a dynamic power adjustment method is applied to automatically adjust the transmission power of the sensor node according to the received signal strength indicator (RSSI), which is related to the distance and obstacle between sensor node and coordinator. The system is evaluated when the user, who wears the sensor, is walking and running. A promising performance is achieved even under body motion. The power consumption can be significantly reduced with this dynamic power adjustment method.

  11. An agar gel membrane-PDMS hybrid microfluidic device for long term single cell dynamic study.

    Science.gov (United States)

    Wong, Ieong; Atsumi, Shota; Huang, Wei-Chih; Wu, Tung-Yun; Hanai, Taizo; Lam, Miu-Ling; Tang, Ping; Yang, Jian; Liao, James C; Ho, Chih-Ming

    2010-10-21

    Significance of single cell measurements stems from the substantial temporal fluctuations and cell-cell variability possessed by individual cells. A major difficulty in monitoring surface non-adherent cells such as bacteria and yeast is that these cells tend to aggregate into clumps during growth, obstructing the tracking or identification of single-cells over long time periods. Here, we developed a microfluidic platform for long term single-cell tracking and cultivation with continuous media refreshing and dynamic chemical perturbation capability. The design highlights a simple device-assembly process between PDMS microchannel and agar membrane through conformal contact, and can be easily adapted by microbiologists for their routine laboratory use. The device confines cell growth in monolayer between an agar membrane and a glass surface. Efficient nutrient diffusion through the membrane and reliable temperature maintenance provide optimal growth condition for the cells, which exhibited fast exponential growth and constant distribution of cell sizes. More than 24 h of single-cell tracking was demonstrated on a transcription-metabolism integrated synthetic biological model, the gene-metabolic oscillator. Single cell morphology study under alcohol toxicity allowed us to discover and characterize cell filamentation exhibited by different E. coli isobutanol tolerant strains. We believe this novel device will bring new capabilities to quantitative microbiology, providing a versatile platform for single cell dynamic studies.

  12. "Is political behavior a viable coping strategy to perceived organizational politics? Unveiling the underlying resource dynamics": Correction to Sun and Chen (2017).

    Science.gov (United States)

    2017-10-01

    Reports an error in "Is Political Behavior a Viable Coping Strategy to Perceived Organizational Politics? Unveiling the Underlying Resource Dynamics" by Shuhua Sun and Huaizhong Chen ( Journal of Applied Psychology , Advanced Online Publication, May 22, 2017, np). In the article, Table 1 contained a formatting error. Correlation coefficient values in the last four cells of column 6 were misplaced with correlation coefficient values in the last four cells of column 7. All versions of this article have been corrected. (The following abstract of the original article appeared in record 2017-22542-001.) We conduct a theory-driven empirical investigation on whether political behavior, as a coping strategy to perceived organizational politics, creates resource trade-offs in moderating the relationship between perceived organizational politics and task performance. Drawing on conservation of resources theory, we hypothesize that political behavior mitigates the adverse effect of perceived organizational politics on task performance via psychological empowerment, yet exacerbates its adverse effect on task performance via emotional exhaustion. Three-wave multisource data from a sample of 222 employees and their 75 supervisors were collected for hypothesis testing. Findings supported our hypotheses. Our study enhances understandings of the complex resource dynamics of using political behavior to cope with perceived organizational politics and highlights the need to move stress-coping research from a focus on the stress-buffering effect of coping on outcomes to a focus on the underlying competing resource dynamics. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  13. Single-step transepithelial ASLA (SCHWIND) with mitomycin-C for the correction of high myopia: long term follow-up.

    Science.gov (United States)

    Aslanides, Ioannis M; Georgoudis, Panagiotis N; Selimis, Vasilis D; Mukherjee, Achyut N

    2015-01-01

    We wanted to compare the outcomes of single-step modified transepithelial photorefractive keratectomy (tPRK) termed a SCHWIND all surface laser ablation (ASLA) versus conventional alcohol-assisted photorefractive keratectomy (PRK) and laser-assisted in situ keratomileusis (LASIK) for the correction of higher myopia of 6.00 diopters (D) or more, in an area with high risk of haze due to high intensity of sunlight. We used a prospective interventional cohort with matched retrospective control groups. Patients with >6 D myopia and 0.05). Mean logMAR (logarithm of the minimum angle of resolution) uncorrected distance visual acuity at 12 months was 0.00 (SD: 0.05), 0.06 (SD: 0.1), and 0.05 (SD: 0.09) in the ASLA, PRK, and LASIK groups, with significantly better vision in the tPRK group versus LASIK (P=0.01) and PRK (P=0.01) groups. ASLA (SCHWIND) tPRK with mitomycin C for high myopia demonstrates comparable refractive outcomes to LASIK and PRK, with relatively favorable visual acuity outcomes. There was no increased incidence of haze in the ASLA group.

  14. Customized versus population-based growth curves: prediction of low body fat percent at term corrected gestational age following preterm birth.

    Science.gov (United States)

    Law, Tameeka L; Katikaneni, Lakshmi D; Taylor, Sarah N; Korte, Jeffrey E; Ebeling, Myla D; Wagner, Carol L; Newman, Roger B

    2012-07-01

    Compare customized versus population-based growth curves for identification of small-for-gestational-age (SGA) and body fat percent (BF%) among preterm infants. Prospective cohort study of 204 preterm infants classified as SGA or appropriate-for-gestational-age (AGA) by population-based and customized growth curves. BF% was determined by air-displacement plethysmography. Differences between groups were compared using bivariable and multivariable linear and logistic regression analyses. Customized curves reclassified 30% of the preterm infants as SGA. SGA infants identified by customized method only had significantly lower BF% (13.8 ± 6.0) than the AGA (16.2 ± 6.3, p = 0.02) infants and similar to the SGA infants classified by both methods (14.6 ± 6.7, p = 0.51). Customized growth curves were a significant predictor of BF% (p = 0.02), whereas population-based growth curves were not a significant independent predictor of BF% (p = 0.50) at term corrected gestational age. Customized growth potential improves the differentiation of SGA infants and low BF% compared with a standard population-based growth curve among a cohort of preterm infants.

  15. Task set induces dynamic reallocation of resources in visual short-term memory.

    Science.gov (United States)

    Sheremata, Summer L; Shomstein, Sarah

    2017-08-01

    Successful interaction with the environment requires the ability to flexibly allocate resources to different locations in the visual field. Recent evidence suggests that visual short-term memory (VSTM) resources are distributed asymmetrically across the visual field based upon task demands. Here, we propose that context, rather than the stimulus itself, determines asymmetrical distribution of VSTM resources. To test whether context modulates the reallocation of resources to the right visual field, task set, defined by memory-load, was manipulated to influence visual short-term memory performance. Performance was measured for single-feature objects embedded within predominantly single- or two-feature memory blocks. Therefore, context was varied to determine whether task set directly predicts changes in visual field biases. In accord with the dynamic reallocation of resources hypothesis, task set, rather than aspects of the physical stimulus, drove improvements in performance in the right- visual field. Our results show, for the first time, that preparation for upcoming memory demands directly determines how resources are allocated across the visual field.

  16. Comparison of the long-term trends in stratospheric dynamics of four reanalyses

    Directory of Open Access Journals (Sweden)

    M. Kozubek

    2017-02-01

    Full Text Available Since the long-term trends of different atmospheric parameters have been already studied separately in many papers, this study is focused on the stratospheric wind (zonal and meridional components and temperature over the whole globe at 10 hPa during 1979–2015. We present the trends for the whole winter (October–March, for each individual month of winter and separately for the period before and after the ozone trend turnaround during the mid-1990s. The change of ozone trends has a clear impact on trends in other investigated stratospheric parameters. Four reanalyses (MERRA, ERA-Interim, JRA-55 and NCEP-DOE are used for comparison. Every grid point is analysed, not zonal averages. The comparison of trends in meridional wind, which is closely connected with Brewer–Dobson circulation, shows a good agreement for all four reanalyses (main features and amplitudes of the trends in terms of winter averages, but there are some differences in individual months, particularly in trend amplitude. These results could be important for studying dynamics (transport in the whole stratosphere.

  17. Effects of motion correction for dynamic [{sup 11}C]Raclopride brain PET data on the evaluation of endogenous dopamine release in striatum

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jae Sung; Kim, Yu Kyeong; Cho, Sang Soo; Lee, Dong Soo; Chung, June Key; Lee, Myung Chul; Kim, Sang Eun [Seoul National University College of Medicine, Seoul (Korea, Republic of); Choe, Yearn Seong [Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of); Kang, Eun Joo [Kangwon University, Chunchon (Korea, Republic of)

    2005-10-15

    Neuroreceptor PET studies require 60-120 minutes to complete and head motion of the subject during the PET scan increases the uncertainty in measured activity. In this study, we investigated the effects of the data-driven head motion correction on the evaluation of endogenous dopamine release (DAR) in the striatum during the motor task which might have caused significant head motion artifact. [{sup 11}C]raclopride PET scans on 4 normal volunteers acquired with bolus plus constant infusion protocol were retrospectively analyzed. Following the 50 min resting period, the participants played a video game with a momentary reward for 40 min. Dynamic frames acquired during the equilibrium condition (pre-task: 30-50 min, task: 70-90 min, post-task:110-120 min) were realigned to the first frame in pre-task condition. Intra-condition registrations between the frames were performed, and average image for each condition was created and registered to the pre-task image (inter-condition registration). Pre-task PET image was then co-registered to own MRI of each participant and transformation parameters were reapplied to the others. Volumes of interest (VOI) for dorsal putamen (PU) and caudate (CA), ventral striatum (VS), and cerebellum were defined on the MRI. Binding potential (BP) was measured and DAR was calculated as the percent change of BP during and after the task. SPM analyses on the BP parametric images were also performed to explore the regional difference in the effects of head motion on BP and DAR estimation. Changes in position and orientation of the striatum during the PET scans were observed before the head motion correction. BP values at pre-task condition were not changed significantly after the intra-condition registration. However, the BP values during and after the task and DAR were significantly changed after the correction. SPM analysis also showed that the extent and significance of the BP differences were significantly changed by the head motion

  18. Effects of motion correction for dynamic [11C]Raclopride brain PET data on the evaluation of endogenous dopamine release in striatum

    International Nuclear Information System (INIS)

    Lee, Jae Sung; Kim, Yu Kyeong; Cho, Sang Soo; Lee, Dong Soo; Chung, June Key; Lee, Myung Chul; Kim, Sang Eun; Choe, Yearn Seong; Kang, Eun Joo

    2005-01-01

    Neuroreceptor PET studies require 60-120 minutes to complete and head motion of the subject during the PET scan increases the uncertainty in measured activity. In this study, we investigated the effects of the data-driven head motion correction on the evaluation of endogenous dopamine release (DAR) in the striatum during the motor task which might have caused significant head motion artifact. [ 11 C]raclopride PET scans on 4 normal volunteers acquired with bolus plus constant infusion protocol were retrospectively analyzed. Following the 50 min resting period, the participants played a video game with a momentary reward for 40 min. Dynamic frames acquired during the equilibrium condition (pre-task: 30-50 min, task: 70-90 min, post-task:110-120 min) were realigned to the first frame in pre-task condition. Intra-condition registrations between the frames were performed, and average image for each condition was created and registered to the pre-task image (inter-condition registration). Pre-task PET image was then co-registered to own MRI of each participant and transformation parameters were reapplied to the others. Volumes of interest (VOI) for dorsal putamen (PU) and caudate (CA), ventral striatum (VS), and cerebellum were defined on the MRI. Binding potential (BP) was measured and DAR was calculated as the percent change of BP during and after the task. SPM analyses on the BP parametric images were also performed to explore the regional difference in the effects of head motion on BP and DAR estimation. Changes in position and orientation of the striatum during the PET scans were observed before the head motion correction. BP values at pre-task condition were not changed significantly after the intra-condition registration. However, the BP values during and after the task and DAR were significantly changed after the correction. SPM analysis also showed that the extent and significance of the BP differences were significantly changed by the head motion correction

  19. Dynamic response of land use and river nutrient concentration to long-term climatic changes.

    Science.gov (United States)

    Bussi, Gianbattista; Janes, Victoria; Whitehead, Paul G; Dadson, Simon J; Holman, Ian P

    2017-07-15

    The combined indirect and direct impacts of land use change and climate change on river water quality were assessed. A land use allocation model was used to evaluate the response of the catchment land use to long-term climatic changes. Its results were used to drive a water quality model and assess the impact of climatic alterations on freshwater nitrate and phosphorus concentrations. Climatic projections were employed to estimate the likelihood of such response. The River Thames catchment (UK) was used as a case-study. If land use is considered as static parameter, according to the model results, climate change alone should reduce the average nitrate concentration, although just by a small amount, by the 2050s in the Lower Thames, due to reduced runoff (and lower export of nitrate from agricultural soils) and increased instream denitrification, and should increase the average phosphorus concentration by 12% by the 2050s in the Lower Thames, due to a reduction of the effluent dilution capacity of the river flow. However, the results of this study also show that these long-term climatic alterations are likely to lead to a reduction in the arable land in the Thames, replaced by improved grassland, due to a decrease in agriculture profitability in the UK. Taking into account the dynamic co-evolution of land use with climate, the average nitrate concentration is expected to be decreased by around 6% by the 2050s in both the upper and the lower Thames, following the model results, and the average phosphorus concentration increased by 13% in the upper Thames and 5% in the lower Thames. On the long term (2080s), nitrate is expected to decrease by 9% and 8% (upper and lower Thames respectively) and phosphorus not to change in the upper thames and increase by 5% in the lower Thames. Copyright © 2017 Elsevier B.V. All rights reserved.

  20. Linear versus Nonlinear Filtering with Scale-Selective Corrections for Balanced Dynamics in a Simple Atmospheric Model

    KAUST Repository

    Subramanian, Aneesh C.

    2012-11-01

    This paper investigates the role of the linear analysis step of the ensemble Kalman filters (EnKF) in disrupting the balanced dynamics in a simple atmospheric model and compares it to a fully nonlinear particle-based filter (PF). The filters have a very similar forecast step but the analysis step of the PF solves the full Bayesian filtering problem while the EnKF analysis only applies to Gaussian distributions. The EnKF is compared to two flavors of the particle filter with different sampling strategies, the sequential importance resampling filter (SIRF) and the sequential kernel resampling filter (SKRF). The model admits a chaotic vortical mode coupled to a comparatively fast gravity wave mode. It can also be configured either to evolve on a so-called slow manifold, where the fast motion is suppressed, or such that the fast-varying variables are diagnosed from the slow-varying variables as slaved modes. Identical twin experiments show that EnKF and PF capture the variables on the slow manifold well as the dynamics is very stable. PFs, especially the SKRF, capture slaved modes better than the EnKF, implying that a full Bayesian analysis estimates the nonlinear model variables better. The PFs perform significantly better in the fully coupled nonlinear model where fast and slow variables modulate each other. This suggests that the analysis step in the PFs maintains the balance in both variables much better than the EnKF. It is also shown that increasing the ensemble size generally improves the performance of the PFs but has less impact on the EnKF after a sufficient number of members have been used.

  1. Linear versus Nonlinear Filtering with Scale-Selective Corrections for Balanced Dynamics in a Simple Atmospheric Model

    KAUST Repository

    Subramanian, Aneesh C.; Hoteit, Ibrahim; Cornuelle, Bruce; Miller, Arthur J.; Song, Hajoon

    2012-01-01

    This paper investigates the role of the linear analysis step of the ensemble Kalman filters (EnKF) in disrupting the balanced dynamics in a simple atmospheric model and compares it to a fully nonlinear particle-based filter (PF). The filters have a very similar forecast step but the analysis step of the PF solves the full Bayesian filtering problem while the EnKF analysis only applies to Gaussian distributions. The EnKF is compared to two flavors of the particle filter with different sampling strategies, the sequential importance resampling filter (SIRF) and the sequential kernel resampling filter (SKRF). The model admits a chaotic vortical mode coupled to a comparatively fast gravity wave mode. It can also be configured either to evolve on a so-called slow manifold, where the fast motion is suppressed, or such that the fast-varying variables are diagnosed from the slow-varying variables as slaved modes. Identical twin experiments show that EnKF and PF capture the variables on the slow manifold well as the dynamics is very stable. PFs, especially the SKRF, capture slaved modes better than the EnKF, implying that a full Bayesian analysis estimates the nonlinear model variables better. The PFs perform significantly better in the fully coupled nonlinear model where fast and slow variables modulate each other. This suggests that the analysis step in the PFs maintains the balance in both variables much better than the EnKF. It is also shown that increasing the ensemble size generally improves the performance of the PFs but has less impact on the EnKF after a sufficient number of members have been used.

  2. Space-based passive microwave soil moisture retrievals and the correction for a dynamic open water fraction

    Directory of Open Access Journals (Sweden)

    B. T. Gouweleeuw

    2012-06-01

    Full Text Available The large observation footprint of low-frequency satellite microwave emissions complicates the interpretation of near-surface soil moisture retrievals. While the effect of sub-footprint lateral heterogeneity is relatively limited under unsaturated conditions, open water bodies (if not accounted for cause a strong positive bias in the satellite-derived soil moisture retrieval. This bias is generally assumed static and associated with large, continental lakes and coastal areas. Temporal changes in the extent of smaller water bodies as small as a few percent of the sensor footprint size, however, can cause significant and dynamic biases. We analysed the influence of such small open water bodies on near-surface soil moisture products derived from actual (non-synthetic data from the Advanced Microwave Scanning Radiometer for the Earth Observing System (AMSR-E for three areas in Oklahoma, USA. Differences between on-ground observations, model estimates and AMSR-E retrievals were related to dynamic estimates of open water fraction, one retrieved from a global daily record based on higher frequency AMSR-E data, a second derived from the Moderate Resolution Imaging Spectroradiometer (MODIS and a third through inversion of the radiative transfer model, used to retrieve soil moisture. The comparison demonstrates the presence of relatively small areas (<0.05 of open water in or near the sensor footprint, possibly in combination with increased, below-critical vegetation density conditions (optical density <0.8, which contribute to seasonally varying biases in excess of 0.2 (m3 m−3 soil water content. These errors need to be addressed, either through elimination or accurate characterisation, if the soil moisture retrievals are to be used effectively in a data assimilation scheme.

  3. Is correction necessary when clinically determining quantitative cerebral perfusion parameters from multi-slice dynamic susceptibility contrast MR studies?

    International Nuclear Information System (INIS)

    Salluzzi, M; Frayne, R; Smith, M R

    2006-01-01

    Several groups have modified the standard singular value decomposition (SVD) algorithm to produce delay-insensitive cerebral blood flow (CBF) estimates from dynamic susceptibility contrast (DSC) perfusion studies. However, new dependences of CBF estimates on bolus arrival times and slice position in multi-slice studies have been recently recognized. These conflicting findings can be reconciled by accounting for several experimental and algorithmic factors. Using simulation and clinical studies, the non-simultaneous measurement of arterial and tissue concentration curves (relative slice position) in a multi-slice study is shown to affect time-related perfusion parameters, e.g. arterial-tissue-delay measurements. However, the current clinical impact of relative slice position on amplitude-related perfusion parameters, e.g. CBF, can be expected to be small unless any of the following conditions are present individually or in combination: (a) high concentration curve signal-to-noise ratios, (b) small tissue mean transit times, (c) narrow arterial input functions or (d) low temporal resolution of the DSC image sequence. Recent improvements in magnetic resonance (MR) technology can easily be expected to lead to scenarios where these effects become increasingly important sources of inaccuracy for all perfusion parameter estimates. We show that using Fourier interpolated (high temporal resolution) residue functions reduces the systematic error of the perfusion parameters obtained from multi-slice studies

  4. Long-term dynamics of OH * temperatures over central Europe: trends and solar correlations

    Directory of Open Access Journals (Sweden)

    C. Kalicinsky

    2016-12-01

    Full Text Available We present the analysis of annual average OH* temperatures in the mesopause region derived from measurements of the Ground-based Infrared P-branch Spectrometer (GRIPS at Wuppertal (51° N, 7° E in the time interval 1988 to 2015. The new study uses a temperature time series which is 7 years longer than that used for the latest analysis regarding the long-term dynamics. This additional observation time leads to a change in characterisation of the observed long-term dynamics. We perform a multiple linear regression using the solar radio flux F10.7 cm (11-year cycle of solar activity and time to describe the temperature evolution. The analysis leads to a linear trend of (−0.089 ± 0.055 K year−1 and a sensitivity to the solar activity of (4.2 ± 0.9 K (100 SFU−1 (r2 of fit 0.6. However, one linear trend in combination with the 11-year solar cycle is not sufficient to explain all observed long-term dynamics. In fact, we find a clear trend break in the temperature time series in the middle of 2008. Before this break point there is an explicit negative linear trend of (−0.24 ± 0.07 K year−1, and after 2008 the linear trend turns positive with a value of (0.64 ± 0.33 K year−1. This apparent trend break can also be described using a long periodic oscillation. One possibility is to use the 22-year solar cycle that describes the reversal of the solar magnetic field (Hale cycle. A multiple linear regression using the solar radio flux and the solar polar magnetic field as parameters leads to the regression coefficients Csolar = (5.0 ± 0.7 K (100 SFU−1 and Chale = (1.8 ±  0.5 K (100 µT−1 (r2 = 0.71. The second way of describing the OH* temperature time series is to use the solar radio flux and an oscillation. A least-square fit leads to a sensitivity to the solar activity of (4.1 ± 0.8 K (100 SFU−1, a period P  =  (24.8 ± 3.3 years, and

  5. Imaging groundwater infiltration dynamics in the karst vadose zone with long-term ERT monitoring

    Science.gov (United States)

    Watlet, Arnaud; Kaufmann, Olivier; Triantafyllou, Antoine; Poulain, Amaël; Chambers, Jonathan E.; Meldrum, Philip I.; Wilkinson, Paul B.; Hallet, Vincent; Quinif, Yves; Van Ruymbeke, Michel; Van Camp, Michel

    2018-03-01

    Water infiltration and recharge processes in karst systems are complex and difficult to measure with conventional hydrological methods. In particular, temporarily saturated groundwater reservoirs hosted in the vadose zone can play a buffering role in water infiltration. This results from the pronounced porosity and permeability contrasts created by local karstification processes of carbonate rocks. Analyses of time-lapse 2-D geoelectrical imaging over a period of 3 years at the Rochefort Cave Laboratory (RCL) site in south Belgium highlight variable hydrodynamics in a karst vadose zone. This represents the first long-term and permanently installed electrical resistivity tomography (ERT) monitoring in a karst landscape. The collected data were compared to conventional hydrological measurements (drip discharge monitoring, soil moisture and water conductivity data sets) and a detailed structural analysis of the local geological structures providing a thorough understanding of the groundwater infiltration. Seasonal changes affect all the imaged areas leading to increases in resistivity in spring and summer attributed to enhanced evapotranspiration, whereas winter is characterised by a general decrease in resistivity associated with a groundwater recharge of the vadose zone. Three types of hydrological dynamics, corresponding to areas with distinct lithological and structural features, could be identified via changes in resistivity: (D1) upper conductive layers, associated with clay-rich soil and epikarst, showing the highest variability related to weather conditions; (D2) deeper and more resistive limestone areas, characterised by variable degrees of porosity and clay contents, hence showing more diffuse seasonal variations; and (D3) a conductive fractured zone associated with damped seasonal dynamics, while showing a great variability similar to that of the upper layers in response to rainfall events. This study provides detailed images of the sources of drip

  6. Imaging groundwater infiltration dynamics in the karst vadose zone with long-term ERT monitoring

    Directory of Open Access Journals (Sweden)

    A. Watlet

    2018-03-01

    Full Text Available Water infiltration and recharge processes in karst systems are complex and difficult to measure with conventional hydrological methods. In particular, temporarily saturated groundwater reservoirs hosted in the vadose zone can play a buffering role in water infiltration. This results from the pronounced porosity and permeability contrasts created by local karstification processes of carbonate rocks. Analyses of time-lapse 2-D geoelectrical imaging over a period of 3 years at the Rochefort Cave Laboratory (RCL site in south Belgium highlight variable hydrodynamics in a karst vadose zone. This represents the first long-term and permanently installed electrical resistivity tomography (ERT monitoring in a karst landscape. The collected data were compared to conventional hydrological measurements (drip discharge monitoring, soil moisture and water conductivity data sets and a detailed structural analysis of the local geological structures providing a thorough understanding of the groundwater infiltration. Seasonal changes affect all the imaged areas leading to increases in resistivity in spring and summer attributed to enhanced evapotranspiration, whereas winter is characterised by a general decrease in resistivity associated with a groundwater recharge of the vadose zone. Three types of hydrological dynamics, corresponding to areas with distinct lithological and structural features, could be identified via changes in resistivity: (D1 upper conductive layers, associated with clay-rich soil and epikarst, showing the highest variability related to weather conditions; (D2 deeper and more resistive limestone areas, characterised by variable degrees of porosity and clay contents, hence showing more diffuse seasonal variations; and (D3 a conductive fractured zone associated with damped seasonal dynamics, while showing a great variability similar to that of the upper layers in response to rainfall events. This study provides detailed images of

  7. Predicting long-term organic carbon dynamics in organically amended soils using the CQESTR model

    Energy Technology Data Exchange (ETDEWEB)

    Plaza, Cesar; Polo, Alfredo [Consejo Superior de Investigaciones Cientificas, Madrid (Spain). Inst. de Ciencias Agrarias; Gollany, Hero T. [Columbia Plateau Conservation Research Center, Pendleton, OR (United States). USDA-ARS; Baldoni, Guido; Ciavatta, Claudio [Bologna Univ. (Italy). Dept. of Agroenvironmental Sciences and Technologies

    2012-04-15

    Purpose: The CQESTR model is a process-based C model recently developed to simulate soil organic matter (SOM) dynamics and uses readily available or easily measurable input parameters. The current version of CQESTR (v. 2.0) has been validated successfully with a number of datasets from agricultural sites in North America but still needs to be tested in other geographic areas and soil types under diverse organic management systems. Materials and methods: We evaluated the predictive performance of CQESTR to simulate long-term (34 years) soil organic C (SOC) changes in a SOM-depleted European soil either unamended or amended with solid manure, liquid manure, or crop residue. Results and discussion: Measured SOC levels declined over the study period in the unamended soil, remained constant in the soil amended with crop residues, and tended to increase in the soils amended with manure, especially with solid manure. Linear regression analysis of measured SOC contents and CQESTR predictions resulted in a correlation coefficient of 0.626 (P < 0.001) and a slope and an intercept not significantly different from 1 and 0, respectively (95% confidence level). The mean squared deviation and root mean square error were relatively small. Simulated values fell within the 95% confidence interval of the measured SOC, and predicted errors were mainly associated with data scattering. Conclusions: The CQESTR model was shown to predict, with a reasonable degree of accuracy, the organic C dynamics in the soils examined. The CQESTR performance, however, could be improved by adding an additional parameter to differentiate between pre-decomposed organic amendments with varying degrees of stability. (orig.)

  8. Long-term population dynamics of a managed burrowing owl colony

    Science.gov (United States)

    Barclay, John H.; Korfanta, Nicole M.; Kauffman, Matthew J.

    2011-01-01

    We analyzed the population dynamics of a burrowing owl (Athene cunicularia) colony at Mineta San Jose International Airport in San Jose, California, USA from 1990-2007. This colony was managed by using artificial burrows to reduce the occurrence of nesting owls along runways and within major airport improvement projects during the study period. We estimated annual reproduction in natural and artificial burrows and age-specific survival rates with mark-recapture techniques, and we estimated the relative contribution of these vital rates to population dynamics using a life table response experiment. The breeding colony showed 2 distinct periods of change: high population growth from 7 nesting pairs in 1991 to 40 pairs in 2002 and population decline to 17 pairs in 2007. Reproduction was highly variable: annual nesting success (pairs that raised =1 young) averaged 79% and ranged from 36% to 100%, whereas fecundity averaged 3.36 juveniles/pair and ranged from 1.43 juveniles/pair to 4.54 juveniles/pair. We estimated annual adult survival at 0.710 during the period of colony increase from 1996 to 2001 and 0.465 during decline from 2002 to 2007, but there was no change in annual survival of juveniles between the 2 time periods. Long-term population growth rate (lambda) estimated from average vital rates was lambdaa=1.072 with lambdai=1.288 during colony increase and lambdad=0.921 (DELTA lambda=0.368) during decline. A life table response experiment showed that change in adult survival rate during increasing and declining phases explained more than twice the variation in growth rate than other vital rates. Our findings suggest that management and conservation of declining burrowing owl populations should address factors that influence adult survival.

  9. Rebuilding after collapse: evidence for long-term cohort dynamics in the native Hawaiian rain forest

    Science.gov (United States)

    Boehmer, Hans Juergen; Wagner, Helene H.; Jacobi, James D.; Gerrish, Grant C.; Mueller-Dombois, Dieter

    2013-01-01

    Questions: Do long-term observations in permanent plots confirm the conceptual model of Metrosideros polymorpha cohort dynamics as postulated in 1987? Do regeneration patterns occur independently of substrate age, i.e. of direct volcanic disturbance impact? Location: The windward mountain slopes of the younger Mauna Loa and the older Mauna Kea volcanoes (island of Hawaii, USA). Methods: After widespread forest decline (dieback), permanent plots were established in 1976 in 13 dieback and 13 non-dieback patches to monitor the population structure of M. polymorpha at ca. 5-yr intervals. Within each plot of 20 × 20 m, all trees with DBH >2.5 cm were individually tagged, measured and tree vigour assessed; regeneration was quantified in 16 systematically placed subplots of 3 × 5 m. Data collected in the subplots included the total number of M. polymorpha seedlings and saplings (five stem height classes). Here we analyse monitoring data from six time steps from 1976 to 2003 using repeated measures ANOVA to test specific predictions derived from the 1987 conceptual model. Results: Regeneration was significantly different between dieback and non-dieback plots. In dieback plots, the collapse in the 1970s was followed by a ‘sapling wave’ that by 2003 led to new cohort stands of M. polymorpha. In non-dieback stands, seedling emergence did not result in sapling waves over the same period. Instead, a ‘sapling gap’ (i.e. very few or no M. polymorpha saplings) prevailed as typical for mature stands. Canopy dieback in 1976, degree of recovery by 2003 and the number of living trees in 2003 were unrelated to substrate age. Conclusions: Population development of M. polymorpha supports the cohort dynamics model, which predicts rebuilding of the forest with the same canopy species after dieback. The lack of association with substrate age suggests that the long-term maintenance of cohort structure in M. polymorpha does not depend on volcanic disturbance but may be related to

  10. SU-G-JeP2-10: On the Need for a Dynamic Model for Patient-Specific Distortion Corrections for MR-Only Pelvis Treatment Planning

    Energy Technology Data Exchange (ETDEWEB)

    Glide-Hurst, C; Zheng, W [Henry Ford Health System, Detroit, MI (United States); Stehning, C; Weiss, S; Renisch, S [Philips Research Laboratories, Hamburg (Germany)

    2016-06-15

    Purpose: Patient-specific distortions, particularly near tissue/air interfaces, require assessment and possible corrections for MRI-only radiation treatment planning (RTP). However, patients are dynamic due to changes in physiological status and motion during imaging sessions. This work investigated the need for dynamic patient-specific distortion corrections to support pelvis MR-only RTP. Methods: The pelvises of healthy volunteers were imaged at 1.0T, 1.5T, and 3.0T. Patient-specific distortion field maps were generated using a dual-echo gradient-recalled echo (GRE) sequence with B0 field maps obtained from the phase difference between the two echoes acquired at two timepoints: empty and full bladders. To quantify changes arising from respiratory state, end-inhalation and end-expiration data were acquired. Distortion map differences were computed between the empty/full bladder and inhalation/expiration to characterize local changes. The normalized frequency distortion distributions in T2-weighted TSE images were characterized, particularly for simulated prostate planning target volumes (PTVs). Results: Changes in rectal and bowel air location were observed, likely due to changes in bladder filling. Within the PTVs, displacement differences (mean ± stdev, range) were −0.02 ± 0.02 mm (−0.13 to 0.07 mm) for 1.0T, −0.1 ± 0.2 mm (−0.92 to 0.74 mm) for 1.5T, and −0.20 ± 0.03 mm (−0.61 to 0.38 mm) for 3.0T. Local changes of ∼1 mm at the prostate-rectal interface were observed for an extreme case at 1.5T. For end-inhale and end-exhale scans at 3.0T, 99% of the voxels had Δx differences within ±0.25mm, thus the displacement differences due to respiratory state appear negligible in the pelvis. Conclusion: Our work suggests that transient bowel/rectal gas due to bladder filling may yield non-negligible patient-specific distortion differences near the prostate/rectal interface, whereas respiration had minimal effect. A temporal patient model for patient

  11. Long-Term Bacterial Dynamics in a Full-Scale Drinking Water Distribution System.

    Directory of Open Access Journals (Sweden)

    E I Prest

    Full Text Available Large seasonal variations in microbial drinking water quality can occur in distribution networks, but are often not taken into account when evaluating results from short-term water sampling campaigns. Temporal dynamics in bacterial community characteristics were investigated during a two-year drinking water monitoring campaign in a full-scale distribution system operating without detectable disinfectant residual. A total of 368 water samples were collected on a biweekly basis at the water treatment plant (WTP effluent and at one fixed location in the drinking water distribution network (NET. The samples were analysed for heterotrophic plate counts (HPC, Aeromonas plate counts, adenosine-tri-phosphate (ATP concentrations, and flow cytometric (FCM total and intact cell counts (TCC, ICC, water temperature, pH, conductivity, total organic carbon (TOC and assimilable organic carbon (AOC. Multivariate analysis of the large dataset was performed to explore correlative trends between microbial and environmental parameters. The WTP effluent displayed considerable seasonal variations in TCC (from 90 × 103 cells mL-1 in winter time up to 455 × 103 cells mL-1 in summer time and in bacterial ATP concentrations (<1-3.6 ng L-1, which were congruent with water temperature variations. These fluctuations were not detected with HPC and Aeromonas counts. The water in the network was predominantly influenced by the characteristics of the WTP effluent. The increase in ICC between the WTP effluent and the network sampling location was small (34 × 103 cells mL-1 on average compared to seasonal fluctuations in ICC in the WTP effluent. Interestingly, the extent of bacterial growth in the NET was inversely correlated to AOC concentrations in the WTP effluent (Pearson's correlation factor r = -0.35, and positively correlated with water temperature (r = 0.49. Collecting a large dataset at high frequency over a two year period enabled the characterization of previously

  12. Long-Term Bacterial Dynamics in a Full-Scale Drinking Water Distribution System

    KAUST Repository

    Prest, E. I.; Weissbrodt, D. G.; Hammes, F.; Van Loosdrecht, M. C M; Vrouwenvelder, Johannes S.

    2016-01-01

    Large seasonal variations in microbial drinking water quality can occur in distribution networks, but are often not taken into account when evaluating results from short-term water sampling campaigns. Temporal dynamics in bacterial community characteristics were investigated during a two-year drinking water monitoring campaign in a full-scale distribution system operating without detectable disinfectant residual. A total of 368 water samples were collected on a biweekly basis at the water treatment plant (WTP) effluent and at one fixed location in the drinking water distribution network (NET). The samples were analysed for heterotrophic plate counts (HPC), Aeromonas plate counts, adenosine-tri-phosphate (ATP) concentrations, and flow cytometric (FCM) total and intact cell counts (TCC, ICC), water temperature, pH, conductivity, total organic carbon (TOC) and assimilable organic carbon (AOC). Multivariate analysis of the large dataset was performed to explore correlative trends between microbial and environmental parameters. The WTP effluent displayed considerable seasonal variations in TCC (from 90 × 103 cells mL-1 in winter time up to 455 × 103 cells mL-1 in summer time) and in bacterial ATP concentrations (<1–3.6 ng L-1), which were congruent with water temperature variations. These fluctuations were not detected with HPC and Aeromonas counts. The water in the network was predominantly influenced by the characteristics of the WTP effluent. The increase in ICC between the WTP effluent and the network sampling location was small (34 × 103 cells mL-1 on average) compared to seasonal fluctuations in ICC in the WTP effluent. Interestingly, the extent of bacterial growth in the NET was inversely correlated to AOC concentrations in the WTP effluent (Pearson’s correlation factor r = -0.35), and positively correlated with water temperature (r = 0.49). Collecting a large dataset at high frequency over a two year period enabled the characterization of previously

  13. Long-Term Bacterial Dynamics in a Full-Scale Drinking Water Distribution System.

    Science.gov (United States)

    Prest, E I; Weissbrodt, D G; Hammes, F; van Loosdrecht, M C M; Vrouwenvelder, J S

    2016-01-01

    Large seasonal variations in microbial drinking water quality can occur in distribution networks, but are often not taken into account when evaluating results from short-term water sampling campaigns. Temporal dynamics in bacterial community characteristics were investigated during a two-year drinking water monitoring campaign in a full-scale distribution system operating without detectable disinfectant residual. A total of 368 water samples were collected on a biweekly basis at the water treatment plant (WTP) effluent and at one fixed location in the drinking water distribution network (NET). The samples were analysed for heterotrophic plate counts (HPC), Aeromonas plate counts, adenosine-tri-phosphate (ATP) concentrations, and flow cytometric (FCM) total and intact cell counts (TCC, ICC), water temperature, pH, conductivity, total organic carbon (TOC) and assimilable organic carbon (AOC). Multivariate analysis of the large dataset was performed to explore correlative trends between microbial and environmental parameters. The WTP effluent displayed considerable seasonal variations in TCC (from 90 × 103 cells mL-1 in winter time up to 455 × 103 cells mL-1 in summer time) and in bacterial ATP concentrations (water temperature variations. These fluctuations were not detected with HPC and Aeromonas counts. The water in the network was predominantly influenced by the characteristics of the WTP effluent. The increase in ICC between the WTP effluent and the network sampling location was small (34 × 103 cells mL-1 on average) compared to seasonal fluctuations in ICC in the WTP effluent. Interestingly, the extent of bacterial growth in the NET was inversely correlated to AOC concentrations in the WTP effluent (Pearson's correlation factor r = -0.35), and positively correlated with water temperature (r = 0.49). Collecting a large dataset at high frequency over a two year period enabled the characterization of previously undocumented seasonal dynamics in the distribution

  14. Long-Term Bacterial Dynamics in a Full-Scale Drinking Water Distribution System

    KAUST Repository

    Prest, E. I.

    2016-10-28

    Large seasonal variations in microbial drinking water quality can occur in distribution networks, but are often not taken into account when evaluating results from short-term water sampling campaigns. Temporal dynamics in bacterial community characteristics were investigated during a two-year drinking water monitoring campaign in a full-scale distribution system operating without detectable disinfectant residual. A total of 368 water samples were collected on a biweekly basis at the water treatment plant (WTP) effluent and at one fixed location in the drinking water distribution network (NET). The samples were analysed for heterotrophic plate counts (HPC), Aeromonas plate counts, adenosine-tri-phosphate (ATP) concentrations, and flow cytometric (FCM) total and intact cell counts (TCC, ICC), water temperature, pH, conductivity, total organic carbon (TOC) and assimilable organic carbon (AOC). Multivariate analysis of the large dataset was performed to explore correlative trends between microbial and environmental parameters. The WTP effluent displayed considerable seasonal variations in TCC (from 90 × 103 cells mL-1 in winter time up to 455 × 103 cells mL-1 in summer time) and in bacterial ATP concentrations (<1–3.6 ng L-1), which were congruent with water temperature variations. These fluctuations were not detected with HPC and Aeromonas counts. The water in the network was predominantly influenced by the characteristics of the WTP effluent. The increase in ICC between the WTP effluent and the network sampling location was small (34 × 103 cells mL-1 on average) compared to seasonal fluctuations in ICC in the WTP effluent. Interestingly, the extent of bacterial growth in the NET was inversely correlated to AOC concentrations in the WTP effluent (Pearson’s correlation factor r = -0.35), and positively correlated with water temperature (r = 0.49). Collecting a large dataset at high frequency over a two year period enabled the characterization of previously

  15. Long-term dynamics of dissolved organic carbon: implications for drinking water supply.

    Science.gov (United States)

    Ledesma, José L J; Köhler, Stephan J; Futter, Martyn N

    2012-08-15

    Surface waters are the main source of drinking water in many regions. Increasing organic carbon concentrations are a cause for concern in Nordic countries since both dissolved and particulate organic carbon can transport contaminants and adversely affect drinking water treatment processes. We present a long-term study of dynamics of total (particulate and dissolved) organic carbon (TOC) concentrations in the River Fyris. This river supplies drinking water to approximately 200000 people in Uppsala, Sweden. The River Fyris is a main tributary to Lake Mälaren, which supplies drinking water to approximately 2 million people in the greater Stockholm area. Utilities responsible for drinking water supply in both Uppsala and Stockholm have expressed concerns about possible increases in TOC. We evaluate organic carbon dynamics within the Fyris catchment by calculating areal mass exports using observed TOC concentrations and modeled flows and by modeling dissolved organic carbon (as a proxy for TOC) using the dynamic, process based INCA-C model. Exports of TOC from the catchment ranged from 0.8 to 5.8 g m(-2) year(-1) in the period 1995-2010. The variation in annual exports was related to climatic variability which influenced seasonality and amount of runoff. Exports and discharge uncoupled at the end of 2008. A dramatic increase in TOC concentrations was observed in 2009, which gradually declined in 2010-2011. INCA-C successfully reproduced the intra- and inter-annual variation in concentrations during 1996-2008 and 2010-2011 but failed to capture the anomalous increase in 2009. We evaluated a number of hypotheses to explain the anomaly in 2009 TOC values, ultimately none proved satisfactory. We draw two main conclusions: there is at least one unknown or unmeasured process controlling or influencing surface water TOC and INCA-C can be used as part of the decision-making process for current and future use of rivers for drinking water supply. Copyright © 2012 Elsevier B

  16. Molecular outflows driven by low-mass protostars. I. Correcting for underestimates when measuring outflow masses and dynamical properties

    Energy Technology Data Exchange (ETDEWEB)

    Dunham, Michael M. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, MS 78, Cambridge, MA 02138 (United States); Arce, Héctor G. [Department of Astronomy, Yale University, P.O. Box 208101, New Haven, CT 06520 (United States); Mardones, Diego [Departamento de Astronomía, Universidad de Chile, Casilla 36-D, Santiago (Chile); Lee, Jeong-Eun [Department of Astronomy and Space Science, Kyung Hee University, Yongin, Gyeonggi 446-701 (Korea, Republic of); Matthews, Brenda C. [National Research Council of Canada, Herzberg Astronomy and Astrophysics, 5071 W. Saanich Road, Victoria, BC V9E 2E7 (Canada); Stutz, Amelia M. [Max-Planck-Institut für Astronomie, Königstuhl 17, D-69117, Heidelberg (Germany); Williams, Jonathan P., E-mail: mdunham@cfa.harvard.edu [Institute for Astronomy, University of Hawaii, Honolulu, HI 96822 (United States)

    2014-03-01

    We present a survey of 28 molecular outflows driven by low-mass protostars, all of which are sufficiently isolated spatially and/or kinematically to fully separate into individual outflows. Using a combination of new and archival data from several single-dish telescopes, 17 outflows are mapped in {sup 12}CO (2-1) and 17 are mapped in {sup 12}CO (3-2), with 6 mapped in both transitions. For each outflow, we calculate and tabulate the mass (M {sub flow}), momentum (P {sub flow}), kinetic energy (E {sub flow}), mechanical luminosity (L {sub flow}), and force (F {sub flow}) assuming optically thin emission in LTE at an excitation temperature, T {sub ex}, of 50 K. We show that all of the calculated properties are underestimated when calculated under these assumptions. Taken together, the effects of opacity, outflow emission at low velocities confused with ambient cloud emission, and emission below the sensitivities of the observations increase outflow masses and dynamical properties by an order of magnitude, on average, and factors of 50-90 in the most extreme cases. Different (and non-uniform) excitation temperatures, inclination effects, and dissociation of molecular gas will all work to further increase outflow properties. Molecular outflows are thus almost certainly more massive and energetic than commonly reported. Additionally, outflow properties are lower, on average, by almost an order of magnitude when calculated from the {sup 12}CO (3-2) maps compared to the {sup 12}CO (2-1) maps, even after accounting for different opacities, map sensitivities, and possible excitation temperature variations. It has recently been argued in the literature that the {sup 12}CO (3-2) line is subthermally excited in outflows, and our results support this finding.

  17. Analytical Modeling of Transient Process In Terms of One-Dimensional Problem of Dynamics With Kinematic Action

    Directory of Open Access Journals (Sweden)

    Kravets Victor V.

    2016-05-01

    Full Text Available One-dimensional dynamic design of a component characterized by inertia coefficient, elastic coefficient, and coefficient of energy dispersion. The component is affected by external action in the form of time-independent initial kinematic disturbances and varying ones. Mathematical model of component dynamics as well as a new form of analytical representation of transient in terms of one-dimensional problem of kinematic effect is provided. Dynamic design of a component is being carried out according to a theory of modal control.

  18. Short-Term Gains, Long-Term Pains: How Cues about State Aid Learning in Dynamic Environments

    Science.gov (United States)

    Gureckis, Todd M.; Love, Bradley C.

    2009-01-01

    Successful investors seeking returns, animals foraging for food, and pilots controlling aircraft all must take into account how their current decisions will impact their future standing. One challenge facing decision makers is that options that appear attractive in the short-term may not turn out best in the long run. In this paper, we explore…

  19. The response of future projections of the North American monsoon when combining dynamical downscaling and bias correction of CCSM4 output

    Science.gov (United States)

    Meyer, Jonathan D. D.; Jin, Jiming

    2017-07-01

    A 20-km regional climate model (RCM) dynamically downscaled the Community Climate System Model version 4 (CCSM4) to compare 32-year historical and future "end-of-the-century" climatologies of the North American Monsoon (NAM). CCSM4 and other phase 5 Coupled Model Intercomparison Project models have indicated a delayed NAM and overall general drying trend. Here, we test the suggested mechanism for this drier NAM where increasing atmospheric static stability and reduced early-season evapotranspiration under global warming will limit early-season convection and compress the mature-season of the NAM. Through our higher resolution RCM, we found the role of accelerated evaporation under a warmer climate is likely understated in coarse resolution models such as CCSM4. Improving the representation of mesoscale interactions associated with the Gulf of California and surrounding topography produced additional surface evaporation, which overwhelmed the convection-suppressing effects of a warmer troposphere. Furthermore, the improved land-sea temperature gradient helped drive stronger southerly winds and greater moisture transport. Finally, we addressed limitations from inherent CCSM4 biases through a form of mean bias correction, which resulted in a more accurate seasonality of the atmospheric thermodynamic profile. After bias correction, greater surface evaporation from average peak GoC SSTs of 32 °C compared to 29 °C from the original CCSM4 led to roughly 50 % larger changes to low-level moist static energy compared to that produced by the downscaled original CCSM4. The increasing destabilization of the NAM environment produced onset dates that were one to 2 weeks earlier in the core of the NAM and northern extent, respectively. Furthermore, a significantly more vigorous NAM signal was produced after bias correction, with >50 mm month-1 increases to the June-September precipitation found along east and west coasts of Mexico and into parts of Texas. A shift towards more

  20. LONG-TERM DYNAMIC MONITORING OF THE HISTORICAL MASONRY FAÇADE: THE CASE OF PALAZZO DUCALE IN VENICE, ITALY

    Directory of Open Access Journals (Sweden)

    J. Noh

    2017-08-01

    Full Text Available Long-term dynamic monitoring of the masonry façade of Palazzo Ducale known as Doge’s palace in Venice, Italy was performed from September 2010 to October 2012. This article demonstrates the results of preliminary analysis on the data set of the first 12-month long monitoring campaign for out-of-plumb dynamic responses of the medieval façade of the monument. The aim of the analysis of the dynamic signals is to validate the data set and investigate dynamic characteristics of the vibration signature of the historical masonry wall in the long-term. Palazzo Ducale is a heavily visited heritage due to its high cultural importance and architectural value. Nevertheless, little is known about the dynamic behaviour of the double-leaf masonry façade. In this study, the dynamic properties of the structure are presented by dynamic identification carried out with the effect of the ambient vibration measured at four different locations on the façade and portico level. The trend and intensity of the vibration at each measurement locations are identified over the year. In addition, the issue on eliminating the noise blended in the signals for reliable analysis are also discussed.

  1. Long-Term Dynamic Monitoring of the Historical Masonry FAÇADE: the Case of Palazzo Ducale in Venice, Italy

    Science.gov (United States)

    Noh, J.; Russo, S.

    2017-08-01

    Long-term dynamic monitoring of the masonry façade of Palazzo Ducale known as Doge's palace in Venice, Italy was performed from September 2010 to October 2012. This article demonstrates the results of preliminary analysis on the data set of the first 12-month long monitoring campaign for out-of-plumb dynamic responses of the medieval façade of the monument. The aim of the analysis of the dynamic signals is to validate the data set and investigate dynamic characteristics of the vibration signature of the historical masonry wall in the long-term. Palazzo Ducale is a heavily visited heritage due to its high cultural importance and architectural value. Nevertheless, little is known about the dynamic behaviour of the double-leaf masonry façade. In this study, the dynamic properties of the structure are presented by dynamic identification carried out with the effect of the ambient vibration measured at four different locations on the façade and portico level. The trend and intensity of the vibration at each measurement locations are identified over the year. In addition, the issue on eliminating the noise blended in the signals for reliable analysis are also discussed.

  2. Long-Term Forest Dynamics and Land-Use Abandonment in the Mediterranean Mountains, Corsica, France

    Directory of Open Access Journals (Sweden)

    Almudena San Roman Sanz

    2013-06-01

    Full Text Available Human practices have had an impact on Mediterranean ecosystems for millennia, particularly through agricultural and pastoral activities. Since the mid-19th century, land-use abandonment has led to the expansion of shrubland and forest, especially in the mountainous areas of the northern Mediterranean basin. Knowledge of these factors is vital to understanding present forest patterns and predicting future forest dynamics in the Mediterranean mountains. We aimed to analyze and understand how land-use abandonment affected spatial modifications of landscapes in two study areas, 44,000 ha and 60,000 ha, located on the island of Corsica, France, representing a typical Mediterranean environment with chestnut forests. Our approach used land-cover archive documents from 1774, 1913, 1975, and 2000, and human population history, 1770 to present day, to describe landscape patterns following land-use abandonment. This research showed that dramatic changes in landscape at the two study areas were caused by the suspension of human influence and the interruption of traditional farming practices. Over the study period, both study sites showed significant reforestation of shrubland and cultivated areas marked by the presence of Quercus ilex forests (+3.40% yr-1 between 1975 and 2000 and by Pinus pinaster (+3.00% yr-1 between 1975 and 2000 at one study site that had experienced heavy rural exodus. At the same time, areas containing chestnut forests decreased by 50% between 1774 and 2000 (-0.09% yr-1 between 1774 and 1975 and -1.42% yr-1 between 1975 and 2000. Shrubland expansion remained limited at both study sites. Our study highlights the value of small-scale approaches for understanding the ecological consequences of land-use abandonment and present and future land-management decisions. Discussion concludes on the importance of working with long-term series for studies on resilience in social-ecological systems and on the consequences in terms of provision of

  3. The importance of the relationship between scale and process in understanding long-term DOC dynamics.

    Science.gov (United States)

    Clark, J M; Bottrell, S H; Evans, C D; Monteith, D T; Bartlett, R; Rose, R; Newton, R J; Chapman, P J

    2010-06-01

    Concentrations of dissolved organic carbon have increased in many, but not all, surface waters across acid impacted areas of Europe and North America over the last two decades. Over the last eight years several hypotheses have been put forward to explain these increases, but none are yet accepted universally. Research in this area appears to have reached a stalemate between those favouring declining atmospheric deposition, climate change or land management as the key driver of long-term DOC trends. While it is clear that many of these factors influence DOC dynamics in soil and stream waters, their effect varies over different temporal and spatial scales. We argue that regional differences in acid deposition loading may account for the apparent discrepancies between studies. DOC has shown strong monotonic increases in areas which have experienced strong downward trends in pollutant sulphur and/or seasalt deposition. Elsewhere climatic factors, that strongly influence seasonality, have also dominated inter-annual variability, and here long-term monotonic DOC trends are often difficult to detect. Furthermore, in areas receiving similar acid loadings, different catchment characteristics could have affected the site specific sensitivity to changes in acidity and therefore the magnitude of DOC release in response to changes in sulphur deposition. We suggest that confusion over these temporal and spatial scales of investigation has contributed unnecessarily to the disagreement over the main regional driver(s) of DOC trends, and that the data behind the majority of these studies is more compatible than is often conveyed. Copyright (c) 2010 Elsevier B.V. All rights reserved.

  4. Simulating the Effects of Short-Term Synaptic Plasticity on Postsynaptic Dynamics in the Globus Pallidus

    Directory of Open Access Journals (Sweden)

    Moran eBrody

    2013-08-01

    Full Text Available The rat globus pallidus (GP is one of the nuclei of the basal ganglia and plays an important role in a variety of motor and cognitive processes. In vivo studies have shown that repetitive stimulation evokes complex modulations of GP activity. In vitro and computational studies have suggested that short-term synaptic plasticity (STP could be one of the underlying mechanisms. The current study used simplified single compartment modeling to explore the possible effect of STP on the activity of GP neurons during low and high frequency stimulation. To do this we constructed a model of a GP neuron connected to a small network of neurons from the three major input sources to GP neurons: striatum (Str, subthalamic nucleus (STN and GP collaterals. All synapses were implemented with a kinetic model of STP. The in vitro recordings of responses to low frequency repetitive stimulation were highly reconstructed, including rate changes and locking to the stimulus. Mainly involved were fast forms of plasticity which have been found at these synapses. . The simulations were qualitatively compared to a data set previously recorded in vitro in our lab. Reconstructions of experimental responses to high frequency stimulation required adding slower forms of plasticity to the STN and GP collateral synapses, as well as adding metabotropic receptors to the STN-GP synapses. These finding suggest the existence of as yet unreported slower short-term dynamics in the GP. The computational model made additional predictions about GP activity during low and high frequency stimulation that may further our understanding of the mechanisms underlying repetative stimulation of the GP.

  5. Long-term ultrasound appearance of concomitant autologous blood and dextranomer/hyaluronic acid copolymer implants: is it associated with successful correction of vesicoureteral reflux?

    Science.gov (United States)

    Kajbafzadeh, Abdol-Mohammad; Aryan, Zahra; Tourchi, Ali; Alizadeh, Houman

    2013-02-01

    To find the association between mound appearance on ultrasound imaging and successful correction of vesicoureteral reflux (VUR). We retrospectively reviewed the ultrasound and voiding cystourethrogram (VCUG) results of patients who underwent dextranomer/hyaluronic acid injection via the hydrodistention injection technique (HIT) or HIT with concomitant autologous blood injection (HABIT) for 5 years postoperatively. VUR resolution at postoperative VCUG was considered as a success. Retained volumes of implants were measured and compared between HABIT and HIT and successful and failed treatments. Presence of mound on ultrasound imaging was also evaluated as a predictor of VUR resolution on VCUG. Measured mound volume was significantly higher in treatments that were successful than in those that were failures (P <.05). During 5-year follow-up, measured mound volumes in the HABIT group were significantly higher than in the HIT group (P <.05). Sensitivity, specificity, positive predictive value, and negative predictive value of mound visualization on the first-month sonography to predict success were 97.7%, 21.5%, 89.6%, and 60%, respectively. These results were dramatically changed for the 50 patients with further VCUG after 1 year of follow-up, with 95.7% sensitivity, 37.0% specificity, 54.0% positive predictive value, and 90.9% negative predictive value. Reduction or absence of the mound after implantation is more frequent among failed treatments in which visualization of the mound on postoperative sonography can predict VUR resolution. Autologous blood injection concomitant with dextranomer/hyaluronic acid implantation results in better immediate and long-term mound preservation, which could possibly be the reason for the higher success rate in HABIT group. Copyright © 2013 Elsevier Inc. All rights reserved.

  6. The Dynamics of the Scientific Potential of Personnel in Terms of the Regions of Ukraine

    Directory of Open Access Journals (Sweden)

    Zhuravka Andrey V.

    2017-11-01

    Full Text Available Innovation development as well as economic growth of the country and its regions depend on the availability of scientific potential of personnel and its effective use. A brief review on this issue has been undertaken. The dynamics of scientific potential of personnel for the period of independence of Ukraine (1991–2015 in all its regions was studied. The scientific potential of personnel is considered in the context of all specialists, performing research and advanced development, and also separately in terms of candidates and doctors of sciences. It has been shown that the number of specialists, performing research and advanced development, across all Ukraine considering the period under review has decreased more than five times. During the same period, the decline in the number of candidates of science was 3,7 times, and in the doctors of science – 1.6 times. A forecast calculation of the number of specialists, performing research and advanced development, on the regression exponential dependence at the level of 2020 showed that it will reach 43,3 thousand persons, which is less than the considered number at the beginning of the «Dobrov period» (46,7 thousand people in 1960.

  7. The metabolic dynamics of cartilage explants over a long-term culture period

    Directory of Open Access Journals (Sweden)

    E.K Moo

    2011-01-01

    Full Text Available INTRODUCTION: Although previous studies have been performed on cartilage explant cultures, the generalized dynamics of cartilage metabolism after extraction from the host are still poorly understood due to differences in the experimental setups across studies, which in turn prevent building a complete picture. METHODS: In this study, we investigated the response of cartilage to the trauma sustained during extraction and determined the time needed for the cartilage to stabilize. Explants were extracted aseptically from bovine metacarpal-phalangeal joints and cultured for up to 17 days. RESULTS: The cell viability, cell number, proteoglycan content, and collagen content of the harvested explants were analyzed at 0, 2, 10, and 17 days after explantation. A high percentage of the cartilage explants were found to be viable. The cell density initially increased significantly but stabilized after two days. The proteoglycan content decreased gradually over time, but it did not decrease to a significant level due to leakage through the distorted peripheral collagen network and into the bathing medium. The collagen content remained stable for most of the culture period until it dropped abruptly on day 17. CONCLUSION: Overall, the tested cartilage explants were sustainable over long-term culture. They were most stable from day 2 to day 10. The degradation of the collagen on day 17 did not reach diseased levels, but it indicated the potential of the cultures to develop into degenerated cartilage. These findings have implications for the application of cartilage explants in pathophysiological fields.

  8. Patient affect experiencing following therapist interventions in short-term dynamic psychotherapy.

    Science.gov (United States)

    Town, Joel M; Hardy, Gillian E; McCullough, Leigh; Stride, Chris

    2012-01-01

    The aim of this research was to examine the relationship between therapist interventions and patient affect responses in Short-Term Dynamic Psychotherapy (STDP). The Affect Experiencing subscale from the Achievement of Therapeutic Objectives Scale (ATOS) was adapted to measure individual immediate affect experiencing (I-AES) responses in relation to therapist interventions coded within the preceding speaking turn, using the Psychotherapy Interaction Coding (PIC) system. A hierarchical linear modelling procedure was used to assess the change in affect experiencing and the relationship between affect experiencing and therapist interventions within and across segments of therapy. Process data was taken from six STDP cases; in total 24 hours of video-taped sessions were examined. Therapist interventions were found to account for a statistically significant amount of variance in immediate affect experiencing. Higher levels of immediate affect experiencing followed the therapist's use of Confrontation, Clarification and Support compared to Questions, Self-disclosure and Information interventions. Therapist Confrontation interventions that attempted to direct pressure towards either the visceral experience of affect or a patient's defences against feelings led to the highest levels of immediate affect experiencing. The type of therapist intervention accounts for a small but significant amount of the variation observed in a patient's immediate emotional arousal. Empirical findings support clinical theory in STDP that suggests strategic verbal responses promote the achievement of this specific therapeutic objective.

  9. Neural dynamics underlying attentional orienting to auditory representations in short-term memory.

    Science.gov (United States)

    Backer, Kristina C; Binns, Malcolm A; Alain, Claude

    2015-01-21

    Sounds are ephemeral. Thus, coherent auditory perception depends on "hearing" back in time: retrospectively attending that which was lost externally but preserved in short-term memory (STM). Current theories of auditory attention assume that sound features are integrated into a perceptual object, that multiple objects can coexist in STM, and that attention can be deployed to an object in STM. Recording electroencephalography from humans, we tested these assumptions, elucidating feature-general and feature-specific neural correlates of auditory attention to STM. Alpha/beta oscillations and frontal and posterior event-related potentials indexed feature-general top-down attentional control to one of several coexisting auditory representations in STM. Particularly, task performance during attentional orienting was correlated with alpha/low-beta desynchronization (i.e., power suppression). However, attention to one feature could occur without simultaneous processing of the second feature of the representation. Therefore, auditory attention to memory relies on both feature-specific and feature-general neural dynamics. Copyright © 2015 the authors 0270-6474/15/351307-12$15.00/0.

  10. CQESTR Simulation of Soil Organic Matter Dynamics in Long-term Agricultural Experiments across USA

    Science.gov (United States)

    Gollany, H.; Liang, Y.; Albrecht, S.; Rickman, R.; Follett, R.; Wilhelm, W.; Novak, J.

    2009-04-01

    Soil organic matter (SOM) has important chemical (supplies nutrients, buffers and adsorbs harmful chemical compounds), biological (supports the growth of microorganisms and micro fauna), and physical (improves soil structure and soil tilth, stores water, and reduces surface crusting, water runoff) functions. The loss of 20 to 50% of soil organic carbon (SOC) from USA soils after converting native prairie or forest to production agriculture is well documented. Sustainable management practices for SOC is critical for maintaining soil productivity and responsible utilization of crop residues. As crop residues are targeted for additional uses (e.g., cellulosic ethanol feedstock) developing C models that predict change in SOM over time with change in management becomes increasingly important. CQESTR, pronounced "sequester," is a process-based C balance model that relates organic residue additions, crop management and soil tillage to SOM accretion or loss. The model works on daily time-steps and can perform long-term (100-year) simulations. Soil organic matter change is computed by maintaining a soil C budget for additions, such as crop residue or added amendments like manure, and organic C losses through microbial decomposition. Our objective was to simulate SOM changes in agricultural soils under a range of soil parent materials, climate and management systems using the CQESTR model. Long-term experiments (e.g. Champaign, IL, >100 yrs; Columbia, MO, >100 yrs; Lincoln, NE, 20 yrs) under various tillage practices, organic amendments, crop rotations, and crop residue removal treatments were selected for their documented history of the long-term effects of management practice on SOM dynamics. Simulated and observed values from the sites were significantly related (r2 = 94%, P management issue. CQESTR successfully simulated a substantial decline in SOM with 90% of crop residue removal for 50 years under various rotations at Columbia, MO and Champaign, IL. An increase in SOM

  11. Modification of the quantum-mechanical equations for the system of charged Dirac particles by including additional tensor terms of the Pauli type. Pt. 1. [Amplified Bethe-Salpeter, radiative corrections, fine structure

    Energy Technology Data Exchange (ETDEWEB)

    Janyszek, H [Uniwersytet Mikolaja Kopernika, Torun (Poland). Instytut Fizyki

    1974-01-01

    A new modified quasirelativistic equation (different from that of Breit) for N charged Dirac particles in the external stationary electromagnetic field is proposed. This equation is an amplified quantum-mechanical Bethe-Salpeter equation obtained by adding (in a semi-phenomenological manner) terms which take into account radiative corrections. The application of this approximate equations is limited to third order terms in the fine structure constant ..cap alpha...

  12. Fixed versus dynamic co-occurrence windows in TextRank term weights for information retrieval

    DEFF Research Database (Denmark)

    Lu, Wei; Cheng, Qikai; Lioma, Christina

    2012-01-01

    iteratively is a score for each vertex, i.e. a term weight, that can be used for information retrieval (IR) just like conventional term frequency based term weights. So far, when computing TextRank term weights over co-occurrence graphs, the window of term co-occurrence is always fixed. This work departs from...

  13. Publisher Correction

    DEFF Research Database (Denmark)

    Turcot, Valérie; Lu, Yingchang; Highland, Heather M

    2018-01-01

    In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article.......In the published version of this paper, the name of author Emanuele Di Angelantonio was misspelled. This error has now been corrected in the HTML and PDF versions of the article....

  14. Author Correction

    DEFF Research Database (Denmark)

    Grundle, D S; Löscher, C R; Krahmann, G

    2018-01-01

    A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper.......A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has not been fixed in the paper....

  15. The SR Approach: a new Estimation Method for Non-Linear and Non-Gaussian Dynamic Term Structure Models

    DEFF Research Database (Denmark)

    Andreasen, Martin Møller; Christensen, Bent Jesper

    This paper suggests a new and easy approach to estimate linear and non-linear dynamic term structure models with latent factors. We impose no distributional assumptions on the factors and they may therefore be non-Gaussian. The novelty of our approach is to use many observables (yields or bonds p...

  16. Nonparametric modeling of US interest rate term structure dynamics and implications on the prices of derivative securities

    NARCIS (Netherlands)

    Jiang, GJ

    1998-01-01

    This paper develops a nonparametric model of interest rate term structure dynamics based an a spot rate process that permits only positive interest rates and a market price of interest rate risk that precludes arbitrage opportunities. Both the spot rate process and the market price of interest rate

  17. Developmental Dynamics of Intergroup Contact and Intergroup Attitudes: Long-Term Effects in Adolescence and Early Adulthood

    NARCIS (Netherlands)

    Wölfer, R.; van Zalk, M.H.W.; Schmid, K.; Hewstone, M.

    2016-01-01

    Intergroup contact represents a powerful way to improve intergroup attitudes and to overcome prejudice and discrimination. However, long-term effects of intergroup contact that consider social network dynamics have rarely been studied at a young age. Study 1 validated an optimized social network

  18. Cotrel-dubousset instrumentation for the correction of adolescent idiopathic scoliosis. Long-term results with an unexpected high revision rate

    Directory of Open Access Journals (Sweden)

    Mueller Franz J

    2012-06-01

    Full Text Available Abstract Background For many years, the CD instrumentation has been regarded as the standard device for the surgical correction of adolescent idiopathic scoliosis (AIS. Nevertheless, scientific long-term results on this procedure are rare. Therefore, we conducted a retrospective follow-up study of patients treated for AIS with CD instrumentation and spondylodesis. Methods A total of 40 patients with AIS underwent CD instrumentation in our department within 3 years and between 1990 and 1992. For the retrospective analysis, first all the patient documents were reviewed, and pre-/postoperative X-ray images as well as those at the latest follow-up were analysed. Furthermore, it was attempted to conduct a clinical survey using the SRS-24 questionnaire, which was sent to the patients after a preceding announcement on the phone. Results Radiologically, the frontal main curvature was improved from a preoperative angle of 69.2° to a postoperative angle of 35.4°, and the secondary curvature was improved from a preoperative angle of 42.6° to a postoperative angle of 20.5°. The latest radiological follow-up at average 57.4 months post surgery showed an average loss of correction of 9.6° (main curvature and 4.6° (secondary curvature, respectively. Within the first 30 days post surgery, 3 out of 40 patients (7.5% received early operative revision for the dislocation of hooks or rods. At an average of 45.7 months (range 11 to 142 months, 19 out of 40 patients (47.5%; including 2 patients with early revision received late operative revisions: The reasons were late infection (10 out of 40 patients; 25% with the development of fistulae (7 cases or putrid secretion (3 cases, which was resolved with the complete removal of instrumentation after all. The average time until revision was 35.5 months (range 14 to 56 months after CD instrumentation. Furthermore, complete implant removal was necessary in 8 out of 40 patients (20% for late operate site

  19. Long-term spatial dynamics of Succisa pratensis in a changing rural landscape: linking dynamical modeling with historical maps

    Czech Academy of Sciences Publication Activity Database

    Herben, Tomáš; Münzbergová, Zuzana; Mildén, M.; Ehrlén, J.; Cousins, S.A.O.; Eriksson, O.

    2006-01-01

    Roč. 94, - (2006), s. 131-143 ISSN 0022-0477 R&D Projects: GA ČR GD206/03/H137 Institutional research plan: CEZ:AV0Z60050516 Keywords : spatial * dynamics * Succisa Subject RIV: EF - Botanics Impact factor: 4.239, year: 2006

  20. Long-term dynamics emerging in floodplains and deltas from the interactions between hydrology and society in a changing climate

    Science.gov (United States)

    Di Baldassarre, Giuliano; Viglione, Alberto; Yan, Kun; Brandimarte, Luigia; Blöschl, Günter

    2014-05-01

    Economic losses and fatalities associated to flood events have increased dramatically over the past decades. This situation might worsen in the near future because of rapid urbanization of many floodplains and deltas, along with enhancement of flood water levels as a result of human interventions, climate variability or sea level rise. To explore future dynamics, we developed a novel approach, which takes into account the dynamic nature of flood risk by an explicit treatment of the interactions and feedbacks between the hydrological and social components of flood risk (i.e. probability of flooding, and potential adverse consequences). In particular, we developed a socio-hydrological model that allows considering how the frequency and magnitude of flooding shapes the evolution of societies, while, at the same time, dynamic societies shape the frequency and magnitude of flooding. We then use this model to simulate long-term dynamics of different types of societies under hydrological change, e.g. increasing flood frequency. Based on the study of long-term dynamics of different floodplains and deltas around the world (e.g. Netherlands, Bangladesh), we identify two main typologies of flood-shaped societies: i) techno-societies, which "fight floods", and typically deal with risk by building and strengthening flood protection structures, such as levees or dikes; and ii) green-societies, which "lives with floods", and mainly cope with risk via adaptation measures, such as resettling out of flood prone areas. The outcomes of this study are relevant for the management of deltas and floodplains as they allow a comparison of long-term dynamics between diverse types of societies in terms of robustness to hydrological change.

  1. Long-term disturbance dynamics and resilience of tropical peat swamp forests.

    Science.gov (United States)

    Cole, Lydia E S; Bhagwat, Shonil A; Willis, Katherine J

    2015-01-01

    1. The coastal peat swamp forests of Sarawak, Malaysian Borneo, are undergoing rapid conversion, predominantly into oil palm plantations. This wetland ecosystem is assumed to have experienced insignificant disturbance in the past, persisting under a single ecologically-stable regime. However, there is limited knowledge of the past disturbance regime, long-term functioning and fundamentally the resilience of this ecosystem to changing natural and anthropogenic perturbations through time. 2. In this study, long-term ecological data sets from three degraded peatlands in Sarawak were collected to shed light on peat swamp forest dynamics. Fossil pollen and charcoal were counted in each sedimentary sequence to reconstruct vegetation and investigate responses to past environmental disturbance, both natural and anthropogenic. 3. Results demonstrate that peat swamp forest taxa have dominated these vegetation profiles throughout the last c . 2000-year period despite the presence of various drivers of disturbance. Evidence for episodes of climatic variability, predominantly linked to ENSO events, and wildfires is present throughout. However, in the last c . 500 years, burning and indicators of human disturbance have elevated beyond past levels at these sites, concurrent with a reduction in peat swamp forest pollen. 4. Two key insights have been gained through this palaeoecological analysis: (i) peat swamp forest vegetation has demonstrated resilience to disturbance caused by burning and climatic variability in Sarawak in the late Holocene, however (ii) coincident with increased fire combined with human impact c . 500 years ago, these communities started to decline. 5. Synthesis . Sarawak's coastal peat swamps have demonstrated resilience to past natural disturbances, with forest vegetation persisting through episodes of fire and climatic variability. However, palaeoecological data presented here suggest that recent, anthropogenic disturbances are of a greater magnitude

  2. Litter quality impacts short- but not long-term soil carbon dynamics in soil aggregate fractions.

    Science.gov (United States)

    Gentile, Roberta; Vanlauwe, Bernard; Six, Johan

    2011-04-01

    Complex molecules are presumed to be preferentially stabilized as soil organic carbon (SOC) based on the generally accepted concept that the chemical composition of litter is a major factor in its rate of decomposition. Hence, a direct link between litter quality and SOC quantity has been assumed, accepted, and ultimately incorporated in SOC models. Here, however, we present data from an incubation and field experiment that refutes the influence of litter quality on the quantity of stabilized SOC. Three different qualities of litter (Tithonia diversifolia, Calliandra calothyrsus, and Zea mays stover; 4 Mg C x ha(-1) yr(-1)) with and without the addition of mineral N fertilizer (0 or 120 kg N x ha(-1)season(-1) were added to a red clay Humic Nitisol in a 3-yr field trial and a 1.5-yr incubation experiment. The litters differed in their concentrations of N, lignin, and polyphenols with the ratio of (lignin + polyphenols): N ranging from 3.5 to 9.8 for the field trial and from 2.3 to 4.0 for the incubation experiment in the order of T. diversifolia stabilized after three annual additions in the field trial. Even within the most sensitive soil aggregate fractions, SOC contents and C:N ratios did not differ with litter quality, indicating that litter quality did not influence the mechanisms by which SOC was stabilized. While increasing litter quality displayed faster decomposition and incorporation of C into soil aggregates after 0.25 yr in the incubation study, all litters resulted in equivalent amounts of C stabilized in the soil after 1.5 yr, further corroborating the results of the field trial. The addition of N fertilizer did not affect SOC stabilization in either the field or the incubation trial. Thus, we conclude that, while litter quality controls shorter-term dynamics of C decomposition and accumulation in the soil, longer-term SOC patterns cannot be predicted based on initial litter quality effects. Hence, the formation and stabilization of SOC is more

  3. Influence of the partial volume correction method on (18)F-fluorodeoxyglucose brain kinetic modelling from dynamic PET images reconstructed with resolution model based OSEM.

    Science.gov (United States)

    Bowen, Spencer L; Byars, Larry G; Michel, Christian J; Chonde, Daniel B; Catana, Ciprian

    2013-10-21

    Kinetic parameters estimated from dynamic (18)F-fluorodeoxyglucose ((18)F-FDG) PET acquisitions have been used frequently to assess brain function in humans. Neglecting partial volume correction (PVC) for a dynamic series has been shown to produce significant bias in model estimates. Accurate PVC requires a space-variant model describing the reconstructed image spatial point spread function (PSF) that accounts for resolution limitations, including non-uniformities across the field of view due to the parallax effect. For ordered subsets expectation maximization (OSEM), image resolution convergence is local and influenced significantly by the number of iterations, the count density, and background-to-target ratio. As both count density and background-to-target values for a brain structure can change during a dynamic scan, the local image resolution may also concurrently vary. When PVC is applied post-reconstruction the kinetic parameter estimates may be biased when neglecting the frame-dependent resolution. We explored the influence of the PVC method and implementation on kinetic parameters estimated by fitting (18)F-FDG dynamic data acquired on a dedicated brain PET scanner and reconstructed with and without PSF modelling in the OSEM algorithm. The performance of several PVC algorithms was quantified with a phantom experiment, an anthropomorphic Monte Carlo simulation, and a patient scan. Using the last frame reconstructed image only for regional spread function (RSF) generation, as opposed to computing RSFs for each frame independently, and applying perturbation geometric transfer matrix PVC with PSF based OSEM produced the lowest magnitude bias kinetic parameter estimates in most instances, although at the cost of increased noise compared to the PVC methods utilizing conventional OSEM. Use of the last frame RSFs for PVC with no PSF modelling in the OSEM algorithm produced the lowest bias in cerebral metabolic rate of glucose estimates, although by less than 5% in

  4. Dissecting long-term adjustments of photoprotective and photo-oxidative stress acclimation occurring in dynamic light environments

    Directory of Open Access Journals (Sweden)

    Shizue Matsubara

    2016-11-01

    Full Text Available Changes in light intensity directly affect the performance of the photosynthetic apparatus. Light energy absorbed in excess of cells’ needs leads to production of reactive oxygen species and photo-oxidative damage. Excess light in both constant and dynamic environments induces photoprotective acclimation in plants. Distinct sets of signals and regulatory mechanisms are involved in acclimatory adjustment of photoprotection and photosynthesis under constant and dynamic (fluctuating light conditions. We are still far away from drawing a comprehensive picture of acclimatory signal transduction pathways, particularly in dynamic environments. In this perspective article, we propose the use of Arabidopsis plants that produce H2O2 in chloroplasts (GO plants under atmospheric CO2 levels as a tool to study the mechanisms of long-term acclimation to photo-oxidative stress. In our opinion there are new avenues to future investigations on acclimatory adjustments and signal transduction occurring in plants under dynamic light environments.

  5. Single-step transepithelial ASLA (SCHWIND with mitomycin-C for the correction of high myopia: long term follow-up

    Directory of Open Access Journals (Sweden)

    Aslanides IM

    2014-12-01

    Full Text Available Ioannis M Aslanides, Panagiotis N Georgoudis, Vasilis D Selimis, Achyut N Mukherjee Emmetropia Mediterranean Eye Institute, Heraklion, Crete, Greece Purpose: We wanted to compare the outcomes of single-step modified transepithelial photorefractive keratectomy (tPRK termed a SCHWIND all surface laser ablation (ASLA versus conventional alcohol-assisted photorefractive keratectomy (PRK and laser-assisted in situ keratomileusis (LASIK for the correction of higher myopia of 6.00 diopters (D or more, in an area with high risk of haze due to high intensity of sunlight.Methods: We used a prospective interventional cohort with matched retrospective control groups. Patients with >6 D myopia and <3.5 D of astigmatism were included. All treatments were performed with the SCHWIND Amaris system using aspheric ablation profiles. Mitomycin C was used in all PRK and ASLA cases. Outcomes were postoperative refraction, visual acuity, stability, and complications. The follow-up period was up to 12 months.Results: In total, 101 eyes were included after exclusions. Mean preoperative spherical equivalent refraction was −7.9 D, −8.2 D, and −7.4 D in the ASLA (n=41, PRK (n=29, and LASIK (n=31 groups. Mean postoperative spherical equivalent at 12 months postoperatively was −0.1 (standard deviation [SD]: 0.34, −0.2 (SD: 0.59, and −0.08 (SD: 0.36 in the ASLA, PRK, and LASIK groups, with 91.4%, 85.7%, and 83.9% within 0.5 D of target, respectively. Refractive outcomes and regression at 12 months did not vary among groups (P>0.05. Mean logMAR (logarithm of the minimum angle of resolution uncorrected distance visual acuity at 12 months was 0.00 (SD: 0.05, 0.06 (SD: 0.1, and 0.05 (SD: 0.09 in the ASLA, PRK, and LASIK groups, with significantly better vision in the tPRK group versus LASIK (P=0.01 and PRK (P=0.01 groups.Conclusion: ASLA (SCHWIND tPRK with mitomycin C for high myopia demonstrates comparable refractive outcomes to LASIK and PRK, with relatively

  6. Predicting nitrogen and acidity effects on long-term dynamics of dissolved organic matter

    International Nuclear Information System (INIS)

    Rowe, E.C.; Tipping, E.; Posch, M.; Oulehle, F.; Cooper, D.M.; Jones, T.G.; Burden, A.; Hall, J.; Evans, C.D.

    2014-01-01

    Increases in dissolved organic carbon (DOC) fluxes may relate to changes in sulphur and nitrogen pollution. We integrated existing models of vegetation growth and soil organic matter turnover, acid–base dynamics, and organic matter mobility, to form the ‘MADOC’ model. After calibrating parameters governing interactions between pH and DOC dissolution using control treatments on two field experiments, MADOC reproduced responses of pH and DOC to additions of acidifying and alkalising solutions. Long-term trends in a range of acid waters were also reproduced. The model suggests that the sustained nature of observed DOC increases can best be explained by a continuously replenishing potentially-dissolved carbon pool, rather than dissolution of a large accumulated store. The simulations informed the development of hypotheses that: DOC increase is related to plant productivity increase as well as to pH change; DOC increases due to nitrogen pollution will become evident, and be sustained, after soil pH has stabilised. -- Highlights: • A model of dissolved organic carbon (DOC) was developed by integrating simple models • MADOC simulates effects of sulphur and nitrogen deposition and interactions with pH. • Responses of DOC and pH to experimental acidification and alkalisation were reproduced. • The persistence of DOC increases will depend on continued supply of potential DOC. • DOC fluxes are likely determined by plant productivity as well as soil solution pH. -- Effects of changes in sulphur and nitrogen pollution on dissolved organic carbon fluxes are predicted by simulating soil organic matter cycling, the release of potentially-dissolved carbon, and interactions with soil pH

  7. Short term outcome of posterior dynamic stabilization system in degenerative lumbar diseases.

    Science.gov (United States)

    Yang, Mingyuan; Li, Chao; Chen, Ziqiang; Bai, Yushu; Li, Ming

    2014-11-01

    Decompression and fusion is considered as the 'gold standard' for the treatment of degenerative lumbar diseases, however, many disadvantages have been reported in several studies, recently like donor site pain, pseudoarthrosis, nonunion, screw loosening, instrumentation failure, infection, adjacent segment disease (ASDis) and degeneration. Dynamic neutralization system (Dynesys) avoids many of these disadvantages. This system is made up of pedicle screws, polyethylene terephthalate cords, and polycarbonate urethane spacers to stabilize the functional spinal unit and preserve the adjacent motion after surgeries. This was a retrospective cohort study to compare the effect of Dynesys for treating degenerative lumbar diseases with posterior lumbar interbody fusion (PLIF) based on short term followup. Seventy five consecutive patients of lumbar degenerative disease operated between October 2010 and November 2012 were studied with a minimum followup of 2 years. Patients were divided into two groups according to the different surgeries. 30 patients underwent decompression and implantation of Dynesys in two levels (n = 29) or three levels (n = 1) and 45 patients underwent PLIF in two levels (n = 39) or three levels (n = 6). Clinical and radiographic outcomes between two groups were reviewed. Thirty patients (male:17, female:13) with a mean age of 55.96 ± 7.68 years were included in Dynesys group and the PLIF group included 45 patients (male:21, female:24) with a mean age of 54.69 ± 3.26 years. The average followup in Dynesys group and PLIF group was 2.22 ± 0.43 year (range 2-3.5 year) and 2.17 ± 0.76 year (range 2-3 year), respectively. Dynesys group showed a shorter operation time (141.06 ± 11.36 min vs. 176.98 ± 6.72 min, P degenerative disease showed clinical benefits with motion preservation of the operated segments, but does not have the significant advantage on motion preservation at adjacent segments, to avoid the degeneration of adjacent intervertebral disk.

  8. Long term picoplankton dynamics in a warm-monomictic, tropical high altitude lake

    Directory of Open Access Journals (Sweden)

    Alfonso LUGO VÁZQUEZ

    2009-08-01

    Full Text Available Long term analyses of the microbial loop, centred on the picoplankton dynamics, were carried out over a five-year (1998 to 2002 period in Lake Alchichica (Puebla, Mexico, a high altitude tropical athalassohaline lake. The hydrodynamics of the lake followed a warm-monomictic pattern with mixing at a minimum temperature during the early dry season while the stratification was pronounced in the late dry season and throughout the rainy season; anoxic conditions in the hypolimnion lasted <9 months. The annual mean concentrations of chlorophyll-a were below 4 μg L-1 in 1998, 1999 and 2001, however, 6.1 and 5.2 μg L-1 in 2000 and 2002, respectively. Total picoplankton, TPP, displayed a temporal pattern that followed the mixing-stratification cycle. The highest TPP values (the whole water column ≥5×106 cells mL-1 were found during mixing and early stratification (January-March. The minimum numbers were present during late stratification (October-November. The maximum TPP numbers were observed within the layer 0-20 m, which corresponded to the epilimnion during the stratification period. Neither the thermocline nor the deep chlorophyll maximum showed an elevated TPP concentration. In the hypolimnion, TPP numbers were low (frequently <1×106 cells mL-1 apparently as a result of the long period of anoxia. Notwithstanding autotrophic picoplankton (APP contributed even ≥30% of TPP (2001 to 2002; no significant correlation was found between TPP and chlorophyll-a.

  9. THE LONG-TERM DYNAMICAL EVOLUTION OF DISK-FRAGMENTED MULTIPLE SYSTEMS IN THE SOLAR NEIGHBORHOOD

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yun [Department of Astronomy, School of Physics, Peking University, Yiheyuan Lu 5, Haidian Qu, Beijing 100871 (China); Kouwenhoven, M. B. N. [Department of Mathematical Sciences, Xi’an Jiaotong-Liverpool University, 111 Ren’ai Road, Suzhou Dushu Lake Science and Education Innovation District, Suzhou Industrial Park, Suzhou 215123 (China); Stamatellos, D. [Jeremiah Horrocks Institute for Mathematics, Physics and Astronomy, University of Central Lancashire, Preston PR1 2HE (United Kingdom); Goodwin, Simon P., E-mail: t.kouwenhoven@xjtlu.edu.cn [Department of Physics and Astronomy, The University of Sheffield, Hicks Building, Hounsfield Road, Sheffield S3 7RH (United Kingdom)

    2016-11-10

    The origin of very low-mass hydrogen-burning stars, brown dwarfs (BDs), and planetary-mass objects (PMOs) at the low-mass end of the initial mass function is not yet fully understood. Gravitational fragmentation of circumstellar disks provides a possible mechanism for the formation of such low-mass objects. The kinematic and binary properties of very low-mass objects formed through disk fragmentation at early times (<10 Myr) were discussed in our previous paper. In this paper we extend the analysis by following the long-term evolution of disk-fragmented systems up to an age of 10 Gyr, covering the ages of the stellar and substellar populations in the Galactic field. We find that the systems continue to decay, although the rates at which companions escape or collide with each other are substantially lower than during the first 10 Myr, and that dynamical evolution is limited beyond 1 Gyr. By t = 10 Gyr, about one third of the host stars are single, and more than half have only one companion left. Most of the other systems have two companions left that orbit their host star in widely separated orbits. A small fraction of companions have formed binaries that orbit the host star in a hierarchical triple configuration. The majority of such double-companion systems have internal orbits that are retrograde with respect to their orbits around their host stars. Our simulations allow a comparison between the predicted outcomes of disk fragmentation with the observed low-mass hydrogen-burning stars, BDs, and PMOs in the solar neighborhood. Imaging and radial velocity surveys for faint binary companions among nearby stars are necessary for verification or rejection of the formation mechanism proposed in this paper.

  10. The solenoidal transport option: IFE drivers, near term research facilities, and beam dynamics

    International Nuclear Information System (INIS)

    Lee, E.P.; Briggs, R.J.

    1997-09-01

    Solenoidal magnets have been used as the beam transport system in all the high current electron induction accelerators that have been built in the past several decades. They have also been considered for the front end transport system for heavy ion accelerators for Inertial Fusion Energy (IFE) drivers, but this option has received very little attention in recent years. The analysis reported here was stimulated mainly by the recent effort to define an affordable open-quotes Integrated Research Experimentclose quotes (IRE) that can meet the near term needs of the IFE program. The 1996 FESAC IFE review panel agreed that an integrated experiment is needed to fully resolve IFE heavy ion driver science and technology issues; specifically, open-quotes the basic beam dynamics issues in the accelerator, the final focusing and transport issues in a reactor-relevant beam parameter regime, and the target heating phenomenologyclose quotes. The development of concepts that can meet these technical objectives and still stay within the severe cost constraints all new fusion proposals will encounter is a formidable challenge. Solenoidal transport has a very favorable scaling as the particle mass is decreased (the main reason why it is preferred for electrons in the region below 50 MeV). This was recognized in a recent conceptual study of high intensity induction linac-based proton accelerators for Accelerator Driven Transmutation Technologies, where solenoidal transport was chosen for the front end. Reducing the ion mass is an obvious scaling to exploit in an IRE design, since the output beam voltage will necessarily be much lower than that of a full scale driver, so solenoids should certainly be considered as one option for this experiment as well

  11. The Use of a Statistical Model of Storm Surge as a Bias Correction for Dynamical Surge Models and its Applicability along the U.S. East Coast

    Directory of Open Access Journals (Sweden)

    Haydee Salmun

    2015-02-01

    Full Text Available The present study extends the applicability of a statistical model for prediction of storm surge originally developed for The Battery, NY in two ways: I. the statistical model is used as a biascorrection for operationally produced dynamical surge forecasts, and II. the statistical model is applied to the region of the east coast of the U.S. susceptible to winter extratropical storms. The statistical prediction is based on a regression relation between the “storm maximum” storm surge and the storm composite significant wave height predicted ata nearby location. The use of the statistical surge prediction as an alternative bias correction for the National Oceanic and Atmospheric Administration (NOAA operational storm surge forecasts is shownhere to be statistically equivalent to the existing bias correctiontechnique and potentially applicable for much longer forecast lead times as well as for storm surge climate prediction. Applying the statistical model to locations along the east coast shows that the regression relation can be “trained” with data from tide gauge measurements and near-shore buoys along the coast from North Carolina to Maine, and that it provides accurate estimates of storm surge.

  12. Long-term dynamic characterization of aeolian desertification in northwest Shanxi, China.

    Science.gov (United States)

    Xue, Zhanjin; Qin, Zuodong; Cheng, Fangqin; Ding, Guangwei; Li, Hongjian

    2017-07-01

    Northwest Shanxi is located on the farming-pastoral ecotone of northern China, where aeolian desertification is one of the most serious environmental and socioeconomic issues. The remote sensing image and geostatistical approach were implemented to estimate aeolian desertified land (ADL) dynamic variations from 1975 to 2015. Results showed that the ADL covered 11,685.21 km 2 (82.29%) of the study area in 2015, the majority of which was classified as a light or moderate degree. The area of ADL gradually expanded at an increasing rate of 87.37 km 2 a -1 during the 1975-2000 periods. More specifically, the area of ADL has increased by 1259.23 km 2 from 1975 to 1990 and by 924.96 km 2 from 1990 to 2000, respectively. In contrast, spatial transfer of ADL areas has dwindled by 2365.85 km 2 with a net decrease of 157.72 km 2 a -1 , and the mitigated areas of aeolian desertification were 10,602.24 km 2 between 2000 and 2015. During the past 40 years, the gravity center of ADL migrated to southeast until 2000 and moved northwest in 2000-2015. From 1975 to 2000, the migration distance of severe ADL was the largest, migrated toward the northwest by 19.03 km in 1975-1990 and by 20.16 km in 1990-2000, respectively. From 2000 to 2015, the migration distance of light ADL was the largest, 27.54 km migrated to the northwest. Aeolian desertification rapidly expanded from 1975 to 2000 under the combination of climate change and intensive human activities. Since the year of 2000, ecological engineering strategy initiated by the governments has been the dominant contributor to the aeolian desertification severity reversal. Aeolian desertification prevention is a complicated process. Both the central and local government should play a critical role in the rehabilitation of ADL in the long term.

  13. Lentiviral-Mediated Gene Therapy in Fanconi Anemia-A Mice Reveals Long-Term Engraftment and Continuous Turnover of Corrected HSCs.

    Science.gov (United States)

    Molina-Estevez, F Javier; Nowrouzi, Ali; Lozano, M Luz; Galy, Anne; Charrier, Sabine; von Kalle, Christof; Guenechea, Guillermo; Bueren, Juan A; Schmidt, Manfred

    2015-01-01

    Fanconi anemia is a DNA repair-deficiency syndrome mainly characterized by cancer predisposition and bone marrow failure. Trying to restore the hematopoietic function in these patients, lentiviral vector-mediated gene therapy trials have recently been proposed. However, because no insertional oncogenesis studies have been conducted so far in DNA repair-deficiency syndromes such as Fanconi anemia, we have carried out a genome-wide screening of lentiviral insertion sites after the gene correction of Fanca(-/-) hematopoietic stem cells (HSCs), using LAM-PCR and 454-pyrosequencing. Our studies first demonstrated that transduction of Fanca(-/-) HSCs with a lentiviral vector designed for clinical application efficiently corrects the phenotype of Fanconi anemia repopulating cells without any sign of toxicity. The identification of more than 6,500 insertion sites in primary and secondary recipients showed a polyclonal pattern of reconstitution, as well as a continuous turnover of corrected Fanca(-/-) HSC clones, without evidences of selection towards specific common integration sites. Taken together our data show, for the first time in a DNA repair-deficiency syndrome, that lentiviral vector-mediated gene therapy efficiently corrects the phenotype of affected HSCs and promotes a healthy pattern of clonal turnover in vivo. These studies will have a particular impact in the development of new gene therapy trials in patients affected by DNA repair syndromes, particularly in Fanconi anemia.

  14. Strength of tensed and compressed concrete segments in crack spacing under short-term dynamic load

    Directory of Open Access Journals (Sweden)

    Galyautdinov Zaur

    2018-01-01

    Full Text Available Formation of model describing dynamic straining of reinforced concrete requires taking into account the basic aspects influencing the stress-strain state of structures. Strength of concrete segments in crack spacing is one of the crucial aspects that affect general strain behavior of reinforced concrete. Experimental results demonstrate significant change in strength of tensed and compressed concrete segments in crack spacing both under static and under dynamic loading. In this case, strength depends on tensile strain level and the slope angle of rebars towards the cracks direction. Existing theoretical and experimental studies estimate strength of concrete segments in crack spacing under static loading. The present work presents results of experimental and theoretical studies of dynamic strength of plates between cracks subjected to compression-tension. Experimental data was analyzed statistically; the dependences were suggested to describe dynamic strength of concrete segments depending on tensile strain level and slope angle of rebars to cracks direction.

  15. Short term outcome of posterior dynamic stabilization system in degenerative lumbar diseases

    Directory of Open Access Journals (Sweden)

    Mingyuan Yang

    2014-01-01

    Conclusion: Dynamic stabilization system treating lumbar degenerative disease showed clinical benefits with motion preservation of the operated segments, but does not have the significant advantage on motion preservation at adjacent segments, to avoid the degeneration of adjacent intervertebral disk.

  16. Long-Term Rotational Dynamics of Defunct Earth-Orbiting Satellites

    Data.gov (United States)

    National Aeronautics and Space Administration — While extensive research has been conducted to predict the trajectories of defunct high altitude satellites, the attitude dynamics of these objects are not well...

  17. Short-term observation of beach dynamics using cross-shore profiles and foreshore sediment

    Digital Repository Service at National Institute of Oceanography (India)

    Dora, G.U.; SanilKumar, V.; Johnson, G.; Philip, C.S.; Vinayaraj, P.

    Cross-shore beach profiles and textural characteristics of foreshore sediment were analyzed for understanding an annual cycle of intertidal beach dynamics at Devbag, an Island sheltered estuarine coast. Cross-shore transects were monitored in a...

  18. Analysis of the long-term availability of uranium: The influence of dynamic constraints and market competition

    International Nuclear Information System (INIS)

    Monnet, Antoine; Gabriel, Sophie; Percebois, Jacques

    2017-01-01

    Abstract: The availability of natural uranium has a direct impact on the global capability to sustain the demand from nuclear power plants in the coming decades. Therefore, the expansion scenarios of nuclear power should be analysed in conjunction with long-term dynamics of the uranium market. This paper presents three forms of a partial-equilibrium model of the uranium market. All forms consider global demand as exogenous (input scenarios from the literature) and regional estimates of the quantities and the costs of ultimate resources (results obtained from previous work). The three forms differ by the market constraints and the market structure considered. Comparing them highlights the role of the market structure and the impact of some key parameters of the market dynamics on the long-term availability of uranium. An important finding is the influence of two constraints: the anticipation of demand and the significant role played by the correlation between price and exploration expenses in shaping the price trends. In addition, results from simulations highlight different long-term dynamics when the producers are allocated into a limited number of regions (to simulate an oligopoly) compared to a single region (undefined number of players to simulate perfect competition). - Highlights: • The growth rate of demand during the 21st century is a key driver of price trends. • Uncertainties on ultimate resources have a limited impact in expansion scenarios. • The price-exploration correlation is a first-order dynamic constraint. • The anticipation of demand is a strong dynamic constraint related to scarcity rent. • The uranium market is better represented by a constrained oligopoly.

  19. Fractional-order leaky integrate-and-fire model with long-term memory and power law dynamics.

    Science.gov (United States)

    Teka, Wondimu W; Upadhyay, Ranjit Kumar; Mondal, Argha

    2017-09-01

    Pyramidal neurons produce different spiking patterns to process information, communicate with each other and transform information. These spiking patterns have complex and multiple time scale dynamics that have been described with the fractional-order leaky integrate-and-Fire (FLIF) model. Models with fractional (non-integer) order differentiation that generalize power law dynamics can be used to describe complex temporal voltage dynamics. The main characteristic of FLIF model is that it depends on all past values of the voltage that causes long-term memory. The model produces spikes with high interspike interval variability and displays several spiking properties such as upward spike-frequency adaptation and long spike latency in response to a constant stimulus. We show that the subthreshold voltage and the firing rate of the fractional-order model make transitions from exponential to power law dynamics when the fractional order α decreases from 1 to smaller values. The firing rate displays different types of spike timing adaptation caused by changes on initial values. We also show that the voltage-memory trace and fractional coefficient are the causes of these different types of spiking properties. The voltage-memory trace that represents the long-term memory has a feedback regulatory mechanism and affects spiking activity. The results suggest that fractional-order models might be appropriate for understanding multiple time scale neuronal dynamics. Overall, a neuron with fractional dynamics displays history dependent activities that might be very useful and powerful for effective information processing. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Publisher Correction

    DEFF Research Database (Denmark)

    Stokholm, Jakob; Blaser, Martin J.; Thorsen, Jonathan

    2018-01-01

    The originally published version of this Article contained an incorrect version of Figure 3 that was introduced following peer review and inadvertently not corrected during the production process. Both versions contain the same set of abundance data, but the incorrect version has the children...

  1. Publisher Correction

    DEFF Research Database (Denmark)

    Flachsbart, Friederike; Dose, Janina; Gentschew, Liljana

    2018-01-01

    The original version of this Article contained an error in the spelling of the author Robert Häsler, which was incorrectly given as Robert Häesler. This has now been corrected in both the PDF and HTML versions of the Article....

  2. Correction to

    DEFF Research Database (Denmark)

    Roehle, Robert; Wieske, Viktoria; Schuetz, Georg M

    2018-01-01

    The original version of this article, published on 19 March 2018, unfortunately contained a mistake. The following correction has therefore been made in the original: The names of the authors Philipp A. Kaufmann, Ronny Ralf Buechel and Bernhard A. Herzog were presented incorrectly....

  3. Effects of dynamical paths on the energy gap and the corrections to the free energy in path integrals of mean-field quantum spin systems

    Science.gov (United States)

    Koh, Yang Wei

    2018-03-01

    In current studies of mean-field quantum spin systems, much attention is placed on the calculation of the ground-state energy and the excitation gap, especially the latter, which plays an important role in quantum annealing. In pure systems, the finite gap can be obtained by various existing methods such as the Holstein-Primakoff transform, while the tunneling splitting at first-order phase transitions has also been studied in detail using instantons in many previous works. In disordered systems, however, it remains challenging to compute the gap of large-size systems with specific realization of disorder. Hitherto, only quantum Monte Carlo techniques are practical for such studies. Recently, Knysh [Nature Comm. 7, 12370 (2016), 10.1038/ncomms12370] proposed a method where the exponentially large dimensionality of such systems is condensed onto a random potential of much lower dimension, enabling efficient study of such systems. Here we propose a slightly different approach, building upon the method of static approximation of the partition function widely used for analyzing mean-field models. Quantum effects giving rise to the excitation gap and nonextensive corrections to the free energy are accounted for by incorporating dynamical paths into the path integral. The time-dependence of the trace of the time-ordered exponential of the effective Hamiltonian is calculated by solving a differential equation perturbatively, yielding a finite-size series expansion of the path integral. Formulae for the first excited-state energy are proposed to aid in computing the gap. We illustrate our approach using the infinite-range ferromagnetic Ising model and the Hopfield model, both in the presence of a transverse field.

  4. Global long-term cost dynamics of offshore wind electricity generation

    NARCIS (Netherlands)

    Gernaat, David E H J; Van Vuuren, Detlef P.; Van Vliet, Jasper; Sullivan, Patrick; Arent, Douglas J.

    2014-01-01

    Using the IMAGE/TIMER (The Targets IMage Energy Regional) long-term integrated assessment model, this paper explores the regional and global potential of offshore wind to contribute to global electricity production. We develop long-term cost supply curve for offshore wind, a representation of the

  5. Factors influencing long term dynamics of health care supply and demand

    NARCIS (Netherlands)

    Smits, M.T.; Roos, E.; Pries-Heje, J.; Chiasson, M.; Wareham, J.; Busquets, X.; Valor, J.

    2012-01-01

    Governments and other policy makers use long-term planning models to support workforce planning decisions for regulating care markets and to ensure accurate balancing between care supply and demand. Our aim is to understand long-term effects of workforce planning decisions on care markets, in order

  6. Correctness of concurrent processes

    NARCIS (Netherlands)

    E.R. Olderog (Ernst-Rüdiger)

    1989-01-01

    textabstractA new notion of correctness for concurrent processes is introduced and investigated. It is a relationship P sat S between process terms P built up from operators of CCS [Mi 80], CSP [Ho 85] and COSY [LTS 79] and logical formulas S specifying sets of finite communication sequences as in

  7. Estimation of dynamic reactivity using an H∞ optimal filter with a nonlinear term

    International Nuclear Information System (INIS)

    Suzuki, Katsuo; Watanabe, Koiti

    1996-01-01

    A method of nonlinear filtering is applied to the problem of estimating the dynamic reactivity of a nonlinear reactor system. The nonlinear filtering algorithm developed is a simple modification of a linear H ∞ optimal filter with a nonlinear feedback loop added. The linear filter is designed on the basis of a linearized dynamical system model that consists of linearized point reactor kinetic equations and a reactivity state equation driven by a fictitious signal. The latter is artificially introduced to deal with the reactivity as a state variable. The results of the computer simulation show that the nonlinear filtering algorithm can be applied to estimate the dynamic reactivity of the nonlinear reactor system, even under relatively large reactivity disturbances

  8. Towards self-correcting quantum memories

    Science.gov (United States)

    Michnicki, Kamil

    This thesis presents a model of self-correcting quantum memories where quantum states are encoded using topological stabilizer codes and error correction is done using local measurements and local dynamics. Quantum noise poses a practical barrier to developing quantum memories. This thesis explores two types of models for suppressing noise. One model suppresses thermalizing noise energetically by engineering a Hamiltonian with a high energy barrier between code states. Thermalizing dynamics are modeled phenomenologically as a Markovian quantum master equation with only local generators. The second model suppresses stochastic noise with a cellular automaton that performs error correction using syndrome measurements and a local update rule. Several ways of visualizing and thinking about stabilizer codes are presented in order to design ones that have a high energy barrier: the non-local Ising model, the quasi-particle graph and the theory of welded stabilizer codes. I develop the theory of welded stabilizer codes and use it to construct a code with the highest known energy barrier in 3-d for spin Hamiltonians: the welded solid code. Although the welded solid code is not fully self correcting, it has some self correcting properties. It has an increased memory lifetime for an increased system size up to a temperature dependent maximum. One strategy for increasing the energy barrier is by mediating an interaction with an external system. I prove a no-go theorem for a class of Hamiltonians where the interaction terms are local, of bounded strength and commute with the stabilizer group. Under these conditions the energy barrier can only be increased by a multiplicative constant. I develop cellular automaton to do error correction on a state encoded using the toric code. The numerical evidence indicates that while there is no threshold, the model can extend the memory lifetime significantly. While of less theoretical importance, this could be practical for real

  9. Field estimates of gravity terrain corrections and Y2K-compatible method to convert from gravity readings with multiple base stations to tide- and long-term drift-corrected observations

    Science.gov (United States)

    Plouff, Donald

    2000-01-01

    Gravity observations are directly made or are obtained from other sources by the U.S. Geological Survey in order to prepare maps of the anomalous gravity field and consequently to interpret the subsurface distribution of rock densities and associated lithologic or geologic units. Observations are made in the field with gravity meters at new locations and at reoccupations of previously established gravity "stations." This report illustrates an interactively-prompted series of steps needed to convert gravity "readings" to values that are tied to established gravity datums and includes computer programs to implement those steps. Inasmuch as individual gravity readings have small variations, gravity-meter (instrument) drift may not be smoothly variable, and acommodations may be needed for ties to previously established stations, the reduction process is iterative. Decision-making by the program user is prompted by lists of best values and graphical displays. Notes about irregularities of topography, which affect the value of observed gravity but are not shown in sufficient detail on topographic maps, must be recorded in the field. This report illustrates ways to record field notes (distances, heights, and slope angles) and includes computer programs to convert field notes to gravity terrain corrections. This report includes approaches that may serve as models for other applications, for example: portrayal of system flow; style of quality control to document and validate computer applications; lack of dependence on proprietary software except source code compilation; method of file-searching with a dwindling list; interactive prompting; computer code to write directly in the PostScript (Adobe Systems Incorporated) printer language; and high-lighting the four-digit year on the first line of time-dependent data sets for assured Y2K compatibility. Computer source codes provided are written in the Fortran scientific language. In order for the programs to operate, they first

  10. Short Term Strategies for a Dynamic Multi-Period Routing Problem

    NARCIS (Netherlands)

    Angelelli, E.; Bianchessi, N.; Mansini, R.; Speranza, M. G.

    2009-01-01

    We consider a Dynamic Multi-Period Routing Problem (DMPRP) faced by a company which deals with on-line pick-up requests and has to serve them by a fleet of uncapacitated vehicles over a finite time horizon. When a request is issued, a deadline of a given number of days d ≤ 2 is associated to it: if

  11. Long-term dynamics of Coxiella burnetii in farmed red deer (Cervus elaphus

    Directory of Open Access Journals (Sweden)

    David eGonzález-Barrio

    2015-12-01

    Full Text Available Several aspects of the dynamics of Coxiella burnetii that are relevant for the implementation of control strategies in ruminant herds with endemic Q-fever are unknown. We designed a longitudinal study to monitor the dynamics of exposure to C. burnetii in a red deer herd with endemic infection in order to allow the design of Q fever specific control approaches. Other relevant aspects of the dynamics of C. burnetii - the effect of herd immune status, age, season and early infection on exposure, the average half-life of antibodies, the presence and duration of maternal humoral immunity and the age of first exposure - were analysed. The dynamics of C. burnetii in deer herds seems to be modulated by host herd and host individual factors and by particular host life history traits. Red deer females become exposed to C. burnetii at the beginning of their second year since maternal antibodies protect them after birth and during the main pathogen shedding season - at the end of spring-early summer. Infection pressure varies between years, probably associated to herd immunity effects, determining inter-annual variation in the risk of exposure. These results suggest that any strategy applied to control C. burnetii in deer herds should be designed to induce immunity in their first year of life immediately after losing maternal antibodies. The short average life of C. burnetii antibodies suggests that any protection based upon humoral immunity would require re-vaccination every 6 months.

  12. Firm Size and Short-Term Dynamics in Aggregate Entry and Exit

    NARCIS (Netherlands)

    Manjon, M.C.

    2004-01-01

    Much of the research on industry dynamics focuses on the interdependence between the sectorial rates of entry and exit.This paper argues that the size of firms and the reaction-adjustment period are important conditions missed in this literature.I illustrate the effects of this omission using data

  13. Comparison of ReLEx SMILE and PRK in terms of visual and refractive outcomes for the correction of low myopia.

    Science.gov (United States)

    Ganesh, Sri; Brar, Sheetal; Patel, Utsav

    2018-06-01

    To compare the objective and subjective quality of vision after femtosecond laser-assisted small incision lenticule extraction (SMILE) and photorefractive keratectomy (PRK) for low myopia. One hundred and twenty eyes from 60 patients (34 females, 26 males) undergoing bilateral correction of low myopia (≤-4 D SE) with either ReLEx SMILE or PRK were included. Visual acuity, contrast sensitivity and higher-order aberrations were recorded preoperatively and compared postoperatively. A quality of vision questionnaire was scored and analyzed 3 months postoperatively. At 3 months, the SMILE group had significantly better uncorrected and corrected distant visual acuity (CDVA), compared to PRK group (p = 0.01). Post-op spherical equivalent (SE) was comparable in both groups (SMILE = -0.15 ± 0.19 D, PRK = -0.14 ± 0.23 D, p = 0.72). However, SE predictability was better in SMILE group with 97% eyes within ±0.05 D compared to 93% eyes in the PRK group. Total higher-order aberrations (HOAs) were significantly higher in PRK compared to the SMILE group (p = 0.022). The SMILE group demonstrated slightly better contrast sensitivity, which was significant at spatial frequency of 12 cpd (p = 0.03). Four eyes in the PRK group had loss of CDVA by one line due to mild haze. Both SMILE and PRK were effective procedures for correction of low myopia. However, SMILE offered superior quality of vision and patient satisfaction due to better postoperative comfort and lower induction of aberrations at 3 months.

  14. Corrective Jaw Surgery

    Medline Plus

    Full Text Available ... out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment of jaws ... out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment of jaws ...

  15. Long-term cognitive outcome of very low birth-weight Saudi preterm infants at the corrected age of 24-36 months.

    Science.gov (United States)

    Sobaih, Badr H

    2018-04-01

    To assess infants' cognitive function at the corrected age of 24-36 months, and to identify factors associated with adverse outcome and examine the correlation between Bayley Infants Neurodevelopmental Screener (BINS) score and Gesell Schedule of Child Development (GSCD). Methods: This retrospective study was performed on Saudi very low birth-weight (VLBW)  infants born   in King Khalid University Hospital, Riyadh, Saudi Arabia between 1997 and 2014 by the use of BINS as screening test and GSCD as definitive test. Results: Of 561 enrolled infants, 367 (65.4%) continued to follow-up. Three-hundred and fifteen infants (85.6%) had a normal cognitive function. In addition to lower birth weight (beta = -0.003) (p less than 0.001), male gender (OR =3.9) (p=0.001)and cerebral palsy (OR =33.9) (p less than 0.001) were the strongest factors associated with poor cognitive outcome. Approximately 75.4% of infants with normal BINS score had normal cognitive function and 7.6% of total infants had sever cognitive impairment. Conclusion: The majority of VLBW infants in our center have  normal cognitive function at the corrected age of 24-36 months. Male gender, lower birth weight, and cerebral palsy are major predictors of poor outcome. The BINS scores were correlated with GSCD as a valid predictor for future developmental outcome.

  16. Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector.

    Science.gov (United States)

    Herzog, R W; Yang, E Y; Couto, L B; Hagstrom, J N; Elwell, D; Fields, P A; Burton, M; Bellinger, D A; Read, M S; Brinkhous, K M; Podsakoff, G M; Nichols, T C; Kurtzman, G J; High, K A

    1999-01-01

    Hemophilia B is a severe X-linked bleeding diathesis caused by the absence of functional blood coagulation factor IX, and is an excellent candidate for treatment of a genetic disease by gene therapy. Using an adeno-associated viral vector, we demonstrate sustained expression (>17 months) of factor IX in a large-animal model at levels that would have a therapeutic effect in humans (up to 70 ng/ml, adequate to achieve phenotypic correction, in an animal injected with 8.5x10(12) vector particles/kg). The five hemophilia B dogs treated showed stable, vector dose-dependent partial correction of the whole blood clotting time and, at higher doses, of the activated partial thromboplastin time. In contrast to other viral gene delivery systems, this minimally invasive procedure, consisting of a series of percutaneous intramuscular injections at a single timepoint, was not associated with local or systemic toxicity. Efficient gene transfer to muscle was shown by immunofluorescence staining and DNA analysis of biopsied tissue. Immune responses against factor IX were either absent or transient. These data provide strong support for the feasibility of the approach for therapy of human subjects.

  17. Management of premature rupture of membranes at term: the need to correct a recurring mistake in articles, chapters, and recommendations of professional organizations.

    Science.gov (United States)

    Krispin, Eyal

    2017-12-01

    Recommendations about the management of premature rupture of membranes at term are based, in part, on a large, randomized controlled trial published in 1996: the TERMPROM trial. The original article contained an error in Table 1, in which "Interval from membrane rupture to delivery" was listed instead of "Interval from membrane rupture to study entry." While the authors and journal corrected this error, the mistake published in the original paper has made its way into subsequent publications and even in guidelines or practice bulletins issued by professional organizations, textbooks, and other publications around the world. The mistake, that half of women with premature rupture of membranes at term who were managed expectantly delivered within 5 hours and 95% delivered within 28 hours of membrane rupture, should be replaced with the actual fact that half of women with premature rupture of membranes at term who were managed expectantly delivered within 33 hours, and 95% delivered within 94-107 hours of membrane rupture. Correcting this error in contemporary health care information and publications is important to counsel patients accurately and to optimize the clinical care of women with premature rupture of membranes at term. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. RNA-Seq reveals dynamic changes of gene expression in key stages of intestine regeneration in the sea cucumber Apostichopus japonicus. [corrected].

    Directory of Open Access Journals (Sweden)

    Lina Sun

    Full Text Available BACKGROUND: Sea cucumbers (Holothuroidea; Echinodermata have the capacity to regenerate lost tissues and organs. Although the histological and cytological aspects of intestine regeneration have been extensively studied, little is known of the genetic mechanisms involved. There has, however, been a renewed effort to develop a database of Expressed Sequence Tags (ESTs in Apostichopus japonicus, an economically-important species that occurs in China. This is important for studies on genetic breeding, molecular markers and special physiological phenomena. We have also constructed a library of ESTs obtained from the regenerative body wall and intestine of A. japonicus. The database has increased to ~30000 ESTs. RESULTS: We used RNA-Seq to determine gene expression profiles associated with intestinal regeneration in A. japonicus at 3, 7, 14 and 21 days post evisceration (dpe. This was compared to profiles obtained from a normally-functioning intestine. Approximately 5 million (M reads were sequenced in every library. Over 2400 up-regulated genes (>10% and over 1000 down-regulated genes (~5% were observed at 3 and 7dpe (log2Ratio ≥ 1, FDR ≤ 0.001. Specific "Go terms" revealed that the DEGs (Differentially Expressed Genes performed an important function at every regeneration stage. Besides some expected pathways (for example, Ribosome and Spliceosome pathway term, the "Notch signaling pathway," the "ECM-receptor interaction" and the "Cytokine-cytokine receptor interaction" were significantly enriched. We also investigated the expression profiles of developmental genes, ECM-associated genes and Cytoskeletal genes. Twenty of the most important differentially expressed genes (DEGs were verified by Real-time PCR, which resulted in a trend concordance of almost 100% between the two techniques. CONCLUSION: Our studies demonstrated dynamic changes in global gene expression during intestine regeneration and presented a series of candidate genes and enriched

  19. Dynamic visual noise affects visual short-term memory for surface color, but not spatial location.

    Science.gov (United States)

    Dent, Kevin

    2010-01-01

    In two experiments participants retained a single color or a set of four spatial locations in memory. During a 5 s retention interval participants viewed either flickering dynamic visual noise or a static matrix pattern. In Experiment 1 memory was assessed using a recognition procedure, in which participants indicated if a particular test stimulus matched the memorized stimulus or not. In Experiment 2 participants attempted to either reproduce the locations or they picked the color from a whole range of possibilities. Both experiments revealed effects of dynamic visual noise (DVN) on memory for colors but not for locations. The implications of the results for theories of working memory and the methodological prospects for DVN as an experimental tool are discussed.

  20. Long-term dynamic loading improves the mechanical properties of chondrogenic mesenchymal stem cell-laden hydrogel

    Directory of Open Access Journals (Sweden)

    AH Huang

    2010-02-01

    Full Text Available Mesenchymal stem cells (MSCs are an attractive cell source for cartilage tissue engineering given their ability to undergo chondrogenesis in 3D culture systems. Mechanical forces play an important role in regulating both cartilage development and MSC chondrogenic gene expression, however, mechanical stimulation has yet to enhance the mechanical properties of engineered constructs. In this study, we applied long-term dynamic compression to MSC-seeded constructs and assessed whether varying pre-culture duration, loading regimens and inclusion of TGF-beta3 during loading would influence functional outcomes and these phenotypic transitions. Loading initiated before chondrogenesis decreased functional maturation, although chondrogenic gene expression increased. In contrast, loading initiated after chondrogenesis and matrix elaboration further improved the mechanical properties of MSC-based constructs, but only when TGF-beta3 levels were maintained and under specific loading parameters. Although matrix quantity was not affected by dynamic compression, matrix distribution, assessed histologically and by FT-IRIS analysis, was significantly improved on the micro- (pericellular and macro- (construct expanse scales. Further, whole genome expression profiling revealed marked shifts in the molecular topography with dynamic loading. These results demonstrate, for the first time, that dynamic compressive loading initiated after a sufficient period of chondro-induction and with sustained TGF-beta exposure enhances matrix distribution and the mechanical properties of MSC-seeded constructs.

  1. Predicting nitrogen and acidity effects on long-term dynamics of dissolved organic matter

    OpenAIRE

    Rowe, E.C.; Tipping, E.; Posch, M.; Oulehle, Filip; Cooper, D.M.; Jones, T.G.; Burden, A.; Hall, J.; Evans, C.D.

    2014-01-01

    Increases in dissolved organic carbon (DOC) fluxes may relate to changes in sulphur and nitrogen pollution. We integrated existing models of vegetation growth and soil organic matter turnover, acid-base dynamics, and organic matter mobility, to form the ‘MADOC’ model. After calibrating parameters governing interactions between pH and DOC dissolution using control treatments on two field experiments, MADOC reproduced responses of pH and DOC to additions of acidifying and alkalising solutions. ...

  2. The Dynamic Relationship between Growth and Profitability under Long-Term Recession: The Case of Korean Construction Companies

    Directory of Open Access Journals (Sweden)

    Seungkyu Yoo

    2015-12-01

    Full Text Available We conducted an empirical analysis of the dynamic relationship between growth and profitability for small- and medium-sized construction companies that faced long-term economic stagnation in Korea. The period of the analysis spanned 2000 to 2014, and the full period was divided into two halves: before the 2008 global financial crisis and after it. Our empirical model was based on the system generalized method of moments model, and 264 construction companies were used as the study sample. The results of the empirical analysis are as follows. (1 A profitability-driven management strategy limits company growth, thus prolonging the economic downturn; (2 When the macroeconomic environment is relatively stable, high growth in the previous period fosters profitability in the current period. This implies that the phenomenon of dynamic increasing returns is present in the Korean construction industry, and learning through growth enhances productivity and profitability. Consequentially, a strategy oriented towards short-term profitability (popular with small- and medium-sized Korean construction companies makes the corporate management less resilient, causing them to select “de-growth” during the long-term stagnation by decreasing their scale of operations. Accordingly, it is important for companies to maintain the balance between growth and profitability.

  3. The relation between short-term emotion dynamics and psychological well-being: A meta-analysis.

    Science.gov (United States)

    Houben, Marlies; Van Den Noortgate, Wim; Kuppens, Peter

    2015-07-01

    Not only how good or bad people feel on average, but also how their feelings fluctuate across time is crucial for psychological health. The last 2 decades have witnessed a surge in research linking various patterns of short-term emotional change to adaptive or maladaptive psychological functioning, often with conflicting results. A meta-analysis was performed to identify consistent relationships between patterns of short-term emotion dynamics-including patterns reflecting emotional variability (measured in terms of within-person standard deviation of emotions across time), emotional instability (measured in terms of the magnitude of consecutive emotional changes), and emotional inertia of emotions over time (measured in terms of autocorrelation)-and relatively stable indicators of psychological well-being or psychopathology. We determined how such relationships are moderated by the type of emotional change, type of psychological well-being or psychopathology involved, valence of the emotion, and methodological factors. A total of 793 effect sizes were identified from 79 articles (N = 11,381) and were subjected to a 3-level meta-analysis. The results confirmed that overall, low psychological well-being co-occurs with more variable (overall ρ̂ = -.178), unstable (overall ρ̂ = -.205), but also more inert (overall ρ̂ = -.151) emotions. These effect sizes were stronger when involving negative compared with positive emotions. Moreover, the results provided evidence for consistency across different types of psychological well-being and psychopathology in their relation with these dynamical patterns, although specificity was also observed. The findings demonstrate that psychological flourishing is characterized by specific patterns of emotional fluctuations across time, and provide insight into what constitutes optimal and suboptimal emotional functioning. (PsycINFO Database Record (c) 2015 APA, all rights reserved).

  4. The Analysis of the Dynamics of the Marketing Services Market in Terms of Strategic Management of Crisis

    Directory of Open Access Journals (Sweden)

    Ivanova Natalya

    2016-12-01

    Full Text Available The aim of the study is to determine the basic modern marketing services according to the dynamics data of the media market of Ukraine. Thus, marketing services are considered as tools that provide crisis man-agement in strategic business development perspective. Scientific and practical significance of the study lies in the results of trend analysis of the dynamics of the media market of Ukraine and its components, the results of which led to the conclusion about the importance of Internet advertising as a modern marketing tool in terms of anti-crisis policy. The study predicted the values of the obtained volumes and market share of Internet advertising in the media market structure in Ukraine for the next period.

  5. Non-minimally coupled quintessence dark energy model with a cubic galileon term: a dynamical system analysis

    Science.gov (United States)

    Bhattacharya, Somnath; Mukherjee, Pradip; Roy, Amit Singha; Saha, Anirban

    2018-03-01

    We consider a scalar field which is generally non-minimally coupled to gravity and has a characteristic cubic Galilean-like term and a generic self-interaction, as a candidate of a Dark Energy model. The system is dynamically analyzed and novel fixed points with perturbative stability are demonstrated. Evolution of the system is numerically studied near a novel fixed point which owes its existence to the Galileon character of the model. It turns out that demanding the stability of this novel fixed point puts a strong restriction on the allowed non-minimal coupling and the choice of the self-interaction. The evolution of the equation of state parameter is studied, which shows that our model predicts an accelerated universe throughout and the phantom limit is only approached closely but never crossed. Our result thus extends the findings of Coley, Dynamical systems and cosmology. Kluwer Academic Publishers, Boston (2013) for more general NMC than linear and quadratic couplings.

  6. Climate change and population dynamics at the tree line: the importance of long-term studies

    Directory of Open Access Journals (Sweden)

    Anfodillo T

    2007-01-01

    Full Text Available Temperature-limited ecosystems are believed to be extremely sensitive to global warming and the upward treeline migration is one of the most relevant phenomenon. Long term monitoring of demographic trends appears essential in order to understand possible effects of higher temperatures on cold ecosystems. Long-term monitoring of natality and mortality of a Pinus sylvestris population in the Swedish Scandes from 1973 to 2005 (Kullman 2007 showed that number of trees increased in the study plots due to higher natality rate, especially in the last decade. This reverses a natural trend of treeline decline and recession occurred in the past.

  7. Correction of dynamic time-activity curves for gamma-camera dead time, radiotracer delivery, and radioactive decay: special considerations with ultrashort-lived radioisotopes

    International Nuclear Information System (INIS)

    Kuruc, A.; Zimmerman, R.E.; Treves, S.

    1985-01-01

    Time-vs.-activity curves obtained by using ultrashort-lived radioisotopes often need to be corrected for the effects of gamma-camera dead time and physical decay. Count loss due to gamma-camera dead time can be monitored by using an electronic oscillator incorporated into the gamma camera. Two algorithms that use this information to correct time-activity curves are discussed. It is also shown that the effect of physical decay on a time-activity curve is dependent on the time course of delivery of the radioisotope to the organ of interest. A mathematical technique that corrects physical decay is described

  8. Behavior control in the sensorimotor loop with short-term synaptic dynamics induced by self-regulating neurons

    Directory of Open Access Journals (Sweden)

    Hazem eToutounji

    2014-05-01

    Full Text Available The behavior and skills of living systems depend on the distributed control provided by specialized and highly recurrent neural networks. Learning and memory in these systems is mediated by a set of adaptation mechanisms, known collectively as neuronal plasticity. Translating principles of recurrent neural control and plasticity to artificial agents has seen major strides, but is usually hampered by the complex interactions between the agent's body and its environment. One of the important standing issues is for the agent to support multiple stable states of behavior, so that its behavioral repertoire matches the requirements imposed by these interactions. The agent also must have the capacity to switch between these states in time scales that are comparable to those by which sensory stimulation varies. Achieving this requires a mechanism of short-term memory that allows the neurocontroller to keep track of the recent history of its input, which finds its biological counterpart in short-term synaptic plasticity. This issue is approached here by deriving synaptic dynamics in recurrent neural networks. Neurons are introduced as self-regulating units with a rich repertoire of dynamics. They exhibit homeostatic properties for certain parameter domains, which result in a set of stable states and the required short-term memory. They can also operate as oscillators, which allow them to surpass the level of activity imposed by their homeostatic operation conditions. Neural systems endowed with the derived synaptic dynamics can be utilized for the neural behavior control of autonomous mobile agents. The resulting behavior depends also on the underlying network structure, which is either engineered, or developed by evolutionary techniques. The effectiveness of these self-regulating units is demonstrated by controlling locomotion of a hexapod with eighteen degrees of freedom, and obstacle-avoidance of a wheel-driven robot.

  9. Integrated modeling of long-term vegetation and hydrologic dynamics in Rocky Mountain watersheds

    Science.gov (United States)

    Robert Steven Ahl

    2007-01-01

    Changes in forest structure resulting from natural disturbances, or managed treatments, can have negative and long lasting impacts on water resources. To facilitate integrated management of forest and water resources, a System for Long-Term Integrated Management Modeling (SLIMM) was developed. By combining two spatially explicit, continuous time models, vegetation...

  10. Time Perspective and Identity Formation: Short-Term Longitudinal Dynamics in College Students

    Science.gov (United States)

    Luyckx, Koen; Lens, Willy; Smits, Ilse; Goossens, Luc

    2010-01-01

    Planning for the future and developing a personalized identity are conceived of as important developmental tasks that adolescents and emerging adults are confronted with on the pathway to adulthood. The present study set out to examine whether both tasks develop in tandem by using a short-term longitudinal dataset consisting of 371 college…

  11. Short- and long-term tannin induced carbon, nitrogen and phosphorus dynamics in Corsican pine litter

    NARCIS (Netherlands)

    Nierop, K.G.J.; Verstraten, J.M.; Tietema, A.; Westerveld, J.W.; Wartenbergh, P.E.

    2006-01-01

    Pine litter amended with either tannic acid (TA) or condensed tannins (CTs) was studied to assess the effects on C, N and P mineralization in relation to the fate of tannins by incubation experiments during various time intervals. TA induced a rapid short-term effect resulting in high C respiration

  12. A method for the automated long-term monitoring of three-spined stickleback Gasterosteus aculeatus shoal dynamics.

    Science.gov (United States)

    Kleinhappel, T K; Al-Zoubi, A; Al-Diri, B; Burman, O; Dickinson, P; John, L; Wilkinson, A; Pike, T W

    2014-04-01

    This paper describes and evaluates a flexible, non-invasive tagging system for the automated identification and long-term monitoring of individual three-spined sticklebacks Gasterosteus aculeatus. The system is based on barcoded tags, which can be reliably and robustly detected and decoded to provide information on an individual's identity and location. Because large numbers of fish can be individually tagged, it can be used to monitor individual- and group-level dynamics within fish shoals. © 2014 The Fisheries Society of the British Isles.

  13. A fast network solution by the decoupled procedure during short-term dynamic processes in power systems

    Energy Technology Data Exchange (ETDEWEB)

    Popovic, D P; Stefanovic, M D [Nikola Tesla Inst., Belgrade (YU). Power System Dept.

    1990-01-01

    A simple, fast and reliable decoupled procedure for solving the network problems during short-term dynamic processes in power systems is presented. It is based on the Newton-Raphson method applied to the power balance equations, which include the effects of generator saliency and non-impedance loads, with further modifications resulting from the physical properties of the phenomena under study. The good convergence characteristics of the developed procedure are demonstrated, and a comparison is made with the traditional method based on the current equation and the triangularized admittance matrix, using the example of stability analysis of the Yugoslav power grid. (author).

  14. The dynamical structure of the MEO region: long-term stability, chaos, and transport

    Science.gov (United States)

    Daquin, Jérôme; Rosengren, Aaron J.; Alessi, Elisa Maria; Deleflie, Florent; Valsecchi, Giovanni B.; Rossi, Alessandro

    2016-04-01

    It has long been suspected that the Global Navigation Satellite Systems exist in a background of complex resonances and chaotic motion; yet, the precise dynamical character of these phenomena remains elusive. Recent studies have shown that the occurrence and nature of the resonances driving these dynamics depend chiefly on the frequencies of nodal and apsidal precession and the rate of regression of the Moon's nodes. Woven throughout the inclination and eccentricity phase space is an exceedingly complicated web-like structure of lunisolar secular resonances, which become particularly dense near the inclinations of the navigation satellite orbits. A clear picture of the physical significance of these resonances is of considerable practical interest for the design of disposal strategies for the four constellations. Here we present analytical and semi-analytical models that accurately reflect the true nature of the resonant interactions, and trace the topological organization of the manifolds on which the chaotic motions take place. We present an atlas of FLI stability maps, showing the extent of the chaotic regions of the phase space, computed through a hierarchy of more realistic, and more complicated, models, and compare the chaotic zones in these charts with the analytical estimation of the width of the chaotic layers from the heuristic Chirikov resonance-overlap criterion. As the semi-major axis of the satellite is receding, we observe a transition from stable Nekhoroshev-like structures at three Earth radii, where regular orbits dominate, to a Chirikov regime where resonances overlap at five Earth radii. From a numerical estimation of the Lyapunov times, we find that many of the inclined, nearly circular orbits of the navigation satellites are strongly chaotic and that their dynamics are unpredictable on decadal timescales.

  15. Herbivore Impact on Tundra Plant Community Dynamics Using Long-term Remote Sensing Observation

    Science.gov (United States)

    Yu, Q.; Engstrom, R.; Shiklomanov, N. I.

    2014-12-01

    Arctic tundra biome is now experiencing dramatic environmental changes accentuated by summer sea-ice decline, permafrost thaw, and shrub expansion. Multi-decadal time-series of the Normalized Difference Vegetation Index (NDVI, a spectral metric of vegetation productivity) shows an overall "greening" trend across the Arctic tundra biome. Regional trends in climate plausibly explain large-scale patterns of increasing plant productivity, as diminished summer sea-ice extent warms the adjacent land causing tundra vegetation to respond positively (increased photosynthetic aboveground biomass). However, at more local scales, there is a great deal of spatial variability in NDVI trends that likely reflects differences in hydrology and soil conditions, disturbance history, and use by wildlife and humans. Particularly, habitat use by large herbivores, such as reindeer and caribou, has large impacts on vegetation dynamics at local and regional scales, but the role of herbivores in modulating the response of vegetation to warming climate has received little attention. This study investigates regional tundra plant community dynamics within inhabits of different sizes of wild caribou/reindeer herds across the Arctic using GIMMS NDVI (Normalized Difference Vegetation Index) 3g data product. The Taimyr herd in Russia is one of the largest herds in the world with a population increase from 450,000 in 1975 to about 1 million animals in 2000. The population of the porcupine caribou herd has fluctuated in the past three decades between 100,000 and 180,000. Time-series of the maximum NDVI within the inhabit area of the Taimyr herd has increased about 2% per decade over the past three decades, while within the inhabit area of the Porcupine herd the maximum NDVI has increased about 5% per decade. Our results indicate that the impact of large herbivores can be detected from space and further analyses on seasonal dynamics of vegetation indices and herbivore behavior may provide more

  16. Comparison of the long-term trends in stratospheric dynamics of four reanalyses

    Czech Academy of Sciences Publication Activity Database

    Kozubek, Michal; Križan, Peter; Laštovička, Jan

    2017-01-01

    Roč. 35, č. 2 (2017), s. 279-294 ISSN 0992-7689 R&D Projects: GA ČR(CZ) GA15-03909S; GA ČR(CZ) GA15-24688S Institutional support: RVO:68378289 Keywords : climatology * general circulation * middle atmosphere dynamic Subject RIV: DG - Athmosphere Sciences, Meteorology OBOR OECD: Meteorology and atmospheric sciences Impact factor: 1.610, year: 2016 http://www.ann-geophys.net/35/279/2017/angeo-35-279-2017.html

  17. Unclassified Source Term and Radionuclide Data for Corrective Action Unit 97: Yucca Flat/Climax Mine, Nevada Test Site, Nevada, Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Peter Martian

    2009-05-01

    This report documents the evaluation of the information and data available on the unclassified source term and radionuclide contamination for CAU 97: Yucca Flat/Climax Mine. The total residual inventory of radionuclides associated with one or more tests is known as the radiologic source term (RST). The RST is comprised of radionuclides in water, glass, or other phases or mineralogic forms. The hydrologic source term (HST) of an underground nuclear test is the portion of the total RST that is released into the groundwater over time following the test. In this report, the HST represents radionuclide release some time after the explosion and does not include the rapidly evolving mechanical, thermal, and chemical processes during the explosion. The CAU 97: Yucca Flat/Climax Mine has many more detonations and a wider variety of settings to consider compared to other CAUs. For instance, the source term analysis and evaluation performed for CAUs 101 and 102: Central and Western Pahute Mesa and CAU 98: Frenchman Flat did not consider vadose zone attenuation because many detonations were located near or below the water table. However, the large number of Yucca Flat/Climax Mine tests and the location of many tests above the water table warrant a more robust analysis of the unsaturated zone.

  18. Generalised Batho correction factor

    International Nuclear Information System (INIS)

    Siddon, R.L.

    1984-01-01

    There are various approximate algorithms available to calculate the radiation dose in the presence of a heterogeneous medium. The Webb and Fox product over layers formulation of the generalised Batho correction factor requires determination of the number of layers and the layer densities for each ray path. It has been shown that the Webb and Fox expression is inefficient for the heterogeneous medium which is expressed as regions of inhomogeneity rather than layers. The inefficiency of the layer formulation is identified as the repeated problem of determining for each ray path which inhomogeneity region corresponds to a particular layer. It has been shown that the formulation of the Batho correction factor as a product over inhomogeneity regions avoids that topological problem entirely. The formulation in terms of a product over regions simplifies the computer code and reduces the time required to calculate the Batho correction factor for the general heterogeneous medium. (U.K.)

  19. Dynamics of entropy perturbations in assisted dark energy with mixed kinetic terms

    International Nuclear Information System (INIS)

    Karwan, Khamphee

    2011-01-01

    We study dynamics of entropy perturbations in the two-field assisted dark energy model. Based on the scenario of assisted dark energy, in which one scalar field is subdominant compared with the other in the early epoch, we show that the entropy perturbations in this two-field system tend to be constant on large scales in the early epoch and hence survive until the present era for a generic evolution of both fields during the radiation and matter eras. This behaviour of the entropy perturbations is preserved even when the fields are coupled via kinetic interaction. Since, for assisted dark energy, the subdominant field in the early epoch becomes dominant at late time, the entropy perturbations can significantly influence the dynamics of density perturbations in the universe. Assuming correlations between the entropy and curvature perturbations, the entropy perturbations can enhance the integrated Sachs-Wolfe (ISW) effect if the signs of the contributions from entropy perturbations and curvature perturbations are opposite after the matter era, otherwise the ISW contribution is suppressed. For canonical scalar field the effect of entropy perturbations on ISW effect is small because the initial value of the entropy perturbations estimated during inflation cannot be sufficiently large. However, in the case of k-essence, the initial value of the entropy perturbations can be large enough to affect the ISW effect to leave a significant imprint on the CMB power spectrum

  20. An analysis of the long-term stability of the particle dynamics in hadron storage rings

    International Nuclear Information System (INIS)

    Bruening, O.S.

    1994-05-01

    This thesis extends the stability analysis of the particle motion in a storage ring and estimates the diffusion rates well inside the dynamic aperture. The calculation of the drift and diffusion coefficients focuses on an application to the proton storage ring in HERA, where the proton beam lifetime drops considerably after the proton and electron beams are brought to collision. The analysis shows that the combined effect of slow and fast modulation frequencies leads to an increased emittance growth in the storage ring. HERA the slow frequency components are caused by ground motion in the HERA tunnel and the fast frequency components by ripples in the power supplies. The thesis provides upper limits for the modultion depths of a fast tune modulation which result in tolerable growth rates for the proton emittance. The analytically calculated drift coefficients agree numerical simulations for the particle dynamics. A comparison of the calculated drift coefficients with those measured in the HERA proton storage ring shows that the analyzed mechanism can lead to growth rates of the same order of magnitude as the ones measured during the luminosity operation in the HERA storage ring. Analytical estimates for the proton growth rates predict a high sensitivity to the particle diffusion on the frequency components of the fast fast tune modulation. This prediction was confirmed by a subsequent modulation experiment in the proton storage ring of HERA, where an external tune modulation with fast frequency components led to a drastic increase in the growth rates

  1. Geometrical modified nesbit corporoplasty to correct different types of penile curvature: description of the surgical procedure based on geometrical principles and long-term results.

    Science.gov (United States)

    Vicini, P; Di Nicola, S; Antonini, G; De Berardinis, E; Gentile, V; De Marco, F

    2016-11-01

    We present the use of a modified corporoplasty, based on geometrical principles, to determine the exact site for the incision in the tunica or plaque and the exact amount of albuginea for overlaying to correct with extreme precision the different types of congenital or acquired penile curvature due to Peyronie's disease. To describe our experience with a new surgical procedure for the enhancement of penile curvature avoiding any overcorrection or undercorrection. Between March 2004 and April 2013, a total of 74 patients underwent the geometrical modified corporoplasty. All patients had congenital curvature until 90° or acquired stable penile curvature 'less' than 60°, that made sexual intercourse very difficult or impossible, normal erectile function, absence of hourglass or hinge effect. Preoperative testing included a physical examination, 3 photographs (frontal, dorsal and lateral) of penis during erection, a 10 mcg PGE1-induced erection and Doppler ultrasound, administration of the International Index of Erectile Function (IIEF-15) questionnaire. A follow-up with postoperative evaluation at 12 weeks, 12 and 24 months, included the same preoperative testing. Satisfaction rates were better assessed with the use of validated questionnaire such as the International Erectile Dysfunction Inventory of the Treatment Satisfaction (EDITS). Statistical analysis with Student's t-test was performed using commercially available, personal computer software. A total of 25 patients had congenital penile curvature with a mean deviation of 46.8° (range 40-90), another 49 patients had Peyronie's disease with a mean deviation of 58.4 (range 45-60). No major complications were reported. Postoperative correction of the curvature was achieved in all patients (100%). Neither undercorrection nor overcorrection were recorded. No significant relapse (curvature>15°) occurred in our patients. Shortening of the penis was reported by 74% but did not influence the high overall

  2. Unclassified Sources Term and Radionuclide Data for Corrective Action Unit 97: Yucca Flat/Climax Mine, Nevada Test Site, Nevada, Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    Peter Martian

    2009-08-01

    This report documents the evaluation of the information and data available on the unclassified source term and radionuclide contamination for CAU 97: Yucca Flat/Climax Mine. The total residual inventory of radionuclides associated with one or more tests is known as the radiologic source term (RST). The RST is comprised of radionuclides in water, glass, or other phases or mineralogic forms. The hydrologic source term (HST) of an underground nuclear test is the portion of the total RST that is released into the groundwater over time following the test. In this report, the HST represents radionuclide release some time after the explosion and does not include the rapidly evolving mechanical, thermal, and chemical processes during the explosion. The CAU 97: Yucca Flat/Climax Mine has many more detonations and a wider variety of settings to consider compared to other CAUs. For instance, the source term analysis and evaluation performed for CAUs 101 and 102: Central and Western Pahute Mesa and CAU 98: Frenchman Flat did not consider vadose zone attenuation because many detonations were located near or below the water table. However, the large number of Yucca Flat/Climax Mine tests and the location of many tests above the water table warrant a more robust analysis of the unsaturated zone. The purpose of this report is to develop and document conceptual models of the Yucca Flat/Climax Mine HST for use in implementing source terms for the Yucca Flat/Climax Mine models. This document presents future plans to incorporate the radionuclide attenuation mechanisms due to unsaturated/multiphase flow and transport within the Yucca Flat CAU scale modeling. The important processes that influence radionuclide migration for the unsaturated and saturated tests in alluvial, volcanic, and carbonate settings are identified. Many different flow and transport models developed by Lawrence Livermore National Laboratory (LLNL) and Los Alamos National Laboratory (LANL), including original

  3. The (lack of) effect of dynamic visual noise on the concreteness effect in short-term memory.

    Science.gov (United States)

    Castellà, Judit; Campoy, Guillermo

    2018-05-17

    It has been suggested that the concreteness effect in short-term memory (STM) is a consequence of concrete words having more distinctive and richer semantic representations. The generation and storage of visual codes in STM could also play a crucial role on the effect because concrete words are more imaginable than abstract words. If this were the case, the introduction of a visual interference task would be expected to disrupt recall of concrete words. A Dynamic Visual Noise (DVN) display, which has been proven to eliminate the concreteness effect on long-term memory (LTM), was presented along encoding of concrete and abstract words in a STM serial recall task. Results showed a main effect of word type, with more item errors in abstract words, a main effect of DVN, which impaired global performance due to more order errors, but no interaction, suggesting that DVN did not have any impact on the concreteness effect. These findings are discussed in terms of LTM participation through redintegration processes and in terms of the language-based models of verbal STM.

  4. Long-term clinical outcomes with the retropubic tension-free vaginal tape (TVT) procedure compared to Burch colposuspension for correcting stress urinary incontinence (SUI).

    Science.gov (United States)

    Holdø, Bjørn; Verelst, Margareta; Svenningsen, Rune; Milsom, Ian; Skjeldestad, Finn Egil

    2017-11-01

    The retropubic tension-free vaginal tape (TVT) procedure replaced Burch colposuspension as the primary surgical method for stress urinary incontinence (SUI) and mixed urinary incontinence (MUI) in women in our department in 1998. In this study we compared the short-term and long-term clinical outcomes of these surgical procedures. Using a case series design, we compared the last 5 years of the Burch procedure (n = 127, 1994-1999) with the first 5 years of the retropubic TVT procedure (n = 180, 1998-2002). Information from the medical records was transferred to a case report form comprising data on perioperative and long-term complications as well as recurrence of UI, defined as bothersome UI or UI in need of repeat surgery. Other endpoints were rates of perioperative and late complications and the rates of prolapse surgery after primary surgery. The data were analyzed with the chi-squared and t tests and survival analysis using SPSS. The cumulative recurrence rate of SUI in women with preoperative SUI was significantly higher after the Burch procedure, but no difference was observed in women with MUI. There were no significant differences in rates of perioperative and late complications. At 12 years there was a significant increase in rates of repeat surgery for incontinence and prolapse in women after the Burch procedure. The long-term efficacy of TVT surgery was superior to that of Burch colposuspension in women with SUI. In addition, the rate of late prolapse surgery was significantly higher after the Burch procedure.

  5. THE BASIC LAWS AND FEATURES OF CYTOKINE DYNAMICS IN PROCESS AND EARLY TERMS AFTER CARDIOPULMONARY BYPASS

    Directory of Open Access Journals (Sweden)

    S. I. Suskov

    2011-01-01

    Full Text Available The basic variants of cytokines reactions defining type of organ dysfunctions are revealed in the course of car- diopulmonary bypass and in the early postoperative period. Their character and expression, depends on gravity preoperative an immunodeficiency and initial degree of heart insufficiency. Diphasic dynamics of development of system inflammatory reaction is confirmed after cardiopulmonary bypass: increase of levels proinflammatory cytokines is in the first phase and anti-inflammatory cytokines with development immunodepression and cellular anergy in is the second phase. Also, key role IL-1Ra is revealed in restraint of hyperactivation of system inflam- matory reaction. Blood whey levels IL-6, IL-8, G-CSF, TNF-α and IL-1Ra should be defined to cardiopulmonary bypass, in 10–12 hours, 24 hours and 3 days after cardiopulmonary bypass and may be used as prognostic criteria of development of postoperative complications. 

  6. Short-term poverty dynamics of rural households: Evidence from Central Sulawesi, Indonesia

    Directory of Open Access Journals (Sweden)

    Stefan Schwarze

    2011-12-01

    Full Text Available The understanding of poverty dynamics is crucial for the design of appropriate poverty reduction strategies. Taking the case of Central Sulawesi, we investigate the determinants of both chronic and transitory poverty using data from 264 randomly selected households interviewed in 2005 and 2007. Regarding the US 1$/day poverty line, the headcount index declined from 19.3% in 2005 to 18.2% in 2007. However, we observed an increasing number of people living on less than US 2$/day expressed in purchasing power parity (PPP. The results of the estimated multinomial logit model applied in this study indicate that a lack of non-agricultural employment opportunities and low endowment of social capital are major determinants of chronic as well as transitory poverty in this province of Indonesia. These results are used to draw policy conclusions with respect to the alleviation of transitory and chronic poverty in Central Sulawesi.

  7. An Examination of Long-Term Environmental-Social Dynamics in the Balkans

    Science.gov (United States)

    Kulkarni, C.; Boger, R. A.

    2015-12-01

    This study examines the interactions of environmental and social dynamics in Central Balkans over the past millennium, a period that experienced three major climatic phases (Medieval Climate Anomaly, Little Ice Age, and the warm 20th century). Meanwhile, the same period witnessed a complex human history with the emergence-rise-decline of the Ottoman Empire and subsequent socio-political events (e.g. wars, famines, migrations). Environmental datasets for the analysis include biological proxies (pollen, spores, and charcoal), geochemical signals through X-ray fluorescence (XRF), and a detailed chronology based on AMS 14C dating of two western and central Serbian lakes while social datasets include historic population data, land use, settlement patterns, and critical historic events derived from a review of the literature and local archives. Among the environmental datasets, indigenous tree and herbaceous pollen from these Central Balkans records demonstrate fluctuations in woodland-grassland dynamics whereas potassium and titanium counts obtained through XRF act as a proxy for surface erosion and clastic input into the lakes. Microscopic charcoal, cereal pollen and subordinate anthropogenic pollen (e.g. cultivated fruits and vegetables) are used to distinguish strong human impact over the landscape. These key anthropogenic indicators create a more thorough social component of the analysis in association with the social datasets. After reconstructing the individual time series for each environmental and social dataset, the two Central Balkan records are correlated in order to identify the environmental and social homogeneity and heterogeneity patterns occurring at shorter and longer timescales during the period. Results provide insights on how a region responds to social and environmental stressors and our approach demonstrates ways to integrate natural and social science system research.

  8. The dynamics of long-term transgene expression in engrafted neural stem cells.

    Science.gov (United States)

    Lee, Jean-Pyo; Tsai, David J; In Park, Kook; Harvey, Alan R; Snyder, Evan Y

    2009-07-01

    To assess the dynamics and confounding variables that influence transgene expression in neural stem cells (NSCs), we generated distinct NSC clones from the same pool of cells, carrying the same reporter gene transcribed from the same promoter, transduced by the same retroviral vector, and transplanted similarly at the same differentiation state, at the same time and location, into the brains of newborn mouse littermates, and monitored in parallel for over a year in vivo (without immunosuppression). Therefore, the sole variables were transgene chromosomal insertion site and copy number. We then adapted and optimized a technique that tests, at the single cell level, persistence of stem cell-mediated transgene expression in vivo based on correlating the presence of the transgene in a given NSC's nucleus (by fluorescence in situ hybridization [FISH]) with the frequency of that transgene's product within the same cell (by combined immunohistochemistry [IHC]). Under the above-stated conditions, insertion site is likely the most contributory variable dictating transgene downregulation in an NSC after 3 months in vivo. We also observed that this obstacle could be effectively and safely counteracted by simple serial infections (as few as three) inserting redundant copies of the transgene into the prospective donor NSC. (The preservation of normal growth control mechanisms and an absence of tumorigenic potential can be readily screened and ensured ex vivo prior to transplantation.) The combined FISH/IHC strategy employed here for monitoring the dynamics of transgene expression at the single cell level in vivo may be used for other types of therapeutic and housekeeping genes in endogenous and exogenous stem cells of many organs and lineages. Copyright 2009 Wiley-Liss, Inc.

  9. Long-term composition dynamics of PAH-containing NAPLs and implications for risk assessment

    International Nuclear Information System (INIS)

    Peters, C.A.; Knightes, C.D.; Brown, D.G.

    1999-01-01

    Subsurface contaminants such as coal tar, creosote, diesel fuel, and other petroleum-derived materials typically exist as very complex chemical mixtures. Risk assessment is useful for site management if a single metric can represent the composition-dependent risk profile of the mixture. This paper examines the factors governing human health risk assessment for multicomponent nonaqueous phase liquids (NAPLs) containing polycyclic aromatic hydrocarbons (PAHs). A model is presented describing the interdependence of the dissolution rates of individual compounds and the shifts in the NAPL composition that occur due to the large differences in aqueous solubilities. The model also accounts for solidification of the less soluble NAPL constituents. Thirty-year numerical simulations describe composition dynamics for natural environmental processes as well as three remediation processes: pump-and-treat, bioremediation, and solvent extraction. Carcinogenic risk due to ingestion of contaminated groundwater at the source is estimated, and its dependence on contaminant removal and NAPL composition shifts is described. When composition dynamics are slow, a compound like naphthalene has great potential to contribute to risk because it may persist in groundwater. When there is significant depletion of the lower molecular weight compounds, the risk is dominated by contributions from compounds such as benzo[a]pyrene. Remediation technologies have the greatest potential for risk reduction if they are effective in removing the more carcinogenic, high molecular weight compounds. Because PAHs can contribute to risk for different reasons and because of the interdependence of their behaviors, compositional approaches lead to better risk predictions for PAHs than simple lumped metrics such as total petroleum hydrocarbon (TPH)

  10. Quantifying and Modelling Long Term Sediment Dynamics in Catchments in Western Europe

    Science.gov (United States)

    Notebaert, B.; De Brue, H.; Verstraeten, G.; Broothaerts, N.

    2015-12-01

    Quantification of sediment dynamics allows to get insight in driving forces and internal dynamics of the sediment cascade system. A useful tool to achieve this is the sediment budget approach, which encompasses the quantification of different sinks and sources. A Holocene time-differentiated sediment budget has been constructed for the Belgian Dijle River catchment (720 km²), based on a large set of field data. The results show how soil erosion is driven by land use changes over longer timescales. Sediment redistribution and the relative importance of the different sinks also vary over time, mainly as a result of changing land use and related landscape connectivity. However, the coarse temporal resolution typically associated with Holocene studies complicates the understanding of sub-millennial scale processes. In a second step, the field-based sediment budget was combined with a modeling approach using Watem/Sedem, a spatially distributed model that simulates soil erosion and colluvial deposition. After validation of the model calibration against the sediment budget, the model was used in a sensitivity analysis. Results confirm the overwhelming influence of human land use on both soil erosion and landscape connectivity, whereas the climatic impact is comparatively small. In addition to catchment-wide simulations, the model also served to test the relative importance of lynchets and dry valleys in different environments. Finally, the geomorphic model was used to simulate past land use, taking into account equifinality. For this purpose, a large series of hypothetical time-independent land use maps of the Dijle catchment were modeled based on a multi-objective allocation algorithm, and applied in Watem/Sedem. Modeled soil erosion and sediment deposition outcomes for each scenario were subsequently compared with the field-based record, taking into account uncertainties. As such, the model allows to evaluate and select realistic land use scenarios for the Holocene.

  11. Dynamics of microbial community during the extremely long-term fermentation process of a traditional soy sauce.

    Science.gov (United States)

    Yang, Yang; Deng, Yue; Jin, Yulan; Liu, Yanxi; Xia, Baixue; Sun, Qun

    2017-08-01

    Soy sauce produced by long-term natural fermentation is a traditional specialty in Asia, with a reputation for superior quality and rich flavour. In this study, both culture-dependent and culture-independent approaches were used to investigate the microbial diversity and community dynamics during an extremely long-term (up to 4 years) natural fermentation of Xianshi Soy Sauce, a national intangible cultural heritage. Genera of Bacillus, Aspergillus and Cladosporium were detected by both methods above. The relative abundance of the genera Bacillus and Weissella was significantly higher in the late stage than in the early one, while the genera Klebsiella and Shimwellia were opposite (P fermentation time, while there was a fair homogeneousness among samples of the same year, especially during the late fermentation stage. The clustering analysis tended to separate the fermented mashes of the 4th year from the earlier stages, suggesting the necessity of the long fermentation period for developing distinctive microbiota and characteristic quality-related compounds. This is the first report to explore the temporal changes in microbial dynamics over a period of 4 years in traditional fermentation of soy sauce, and this work illustrated the importance of isolation of appropriate strains to be used as starter cultures in brewing processes. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  12. A Portable Dynamic Laser Speckle System for Sensing Long-Term Changes Caused by Treatments in Painting Conservation.

    Science.gov (United States)

    Pérez, Alberto J; González-Peña, Rolando J; Braga, Roberto; Perles, Ángel; Pérez-Marín, Eva; García-Diego, Fernando J

    2018-01-11

    Dynamic laser speckle (DLS) is used as a reliable sensor of activity for all types of materials. Traditional applications are based on high-rate captures (usually greater than 10 frames-per-second, fps). Even for drying processes in conservation treatments, where there is a high level of activity in the first moments after the application and slower activity after some minutes or hours, the process is based on the acquisition of images at a time rate that is the same in moments of high and low activity. In this work, we present an alternative approach to track the drying process of protective layers and other painting conservation processes that take a long time to reduce their levels of activity. We illuminate, using three different wavelength lasers, a temporary protector (cyclododecane) and a varnish, and monitor them using a low fps rate during long-term drying. The results are compared to the traditional method. This work also presents a monitoring method that uses portable equipment. The results present the feasibility of using the portable device and show the improved sensitivity of the dynamic laser speckle when sensing the long-term process for drying cyclododecane and varnish in conservation.

  13. A Portable Dynamic Laser Speckle System for Sensing Long-Term Changes Caused by Treatments in Painting Conservation

    Science.gov (United States)

    Pérez, Alberto J.; Braga, Roberto; Perles, Ángel; Pérez–Marín, Eva; García-Diego, Fernando J.

    2018-01-01

    Dynamic laser speckle (DLS) is used as a reliable sensor of activity for all types of materials. Traditional applications are based on high-rate captures (usually greater than 10 frames-per-second, fps). Even for drying processes in conservation treatments, where there is a high level of activity in the first moments after the application and slower activity after some minutes or hours, the process is based on the acquisition of images at a time rate that is the same in moments of high and low activity. In this work, we present an alternative approach to track the drying process of protective layers and other painting conservation processes that take a long time to reduce their levels of activity. We illuminate, using three different wavelength lasers, a temporary protector (cyclododecane) and a varnish, and monitor them using a low fps rate during long-term drying. The results are compared to the traditional method. This work also presents a monitoring method that uses portable equipment. The results present the feasibility of using the portable device and show the improved sensitivity of the dynamic laser speckle when sensing the long-term process for drying cyclododecane and varnish in conservation. PMID:29324692

  14. Long-term spatiotemporal stability and dynamic changes in helminth infracommunities of bank voles (Myodes glareolus) in NE Poland.

    Science.gov (United States)

    Grzybek, Maciej; Bajer, Anna; Bednarska, Małgorzata; Al-Sarraf, Mohammed; Behnke-Borowczyk, Jolanta; Harris, Philip D; Price, Stephen J; Brown, Gabrielle S; Osborne, Sarah-Jane; Siński, Edward; Behnke, Jerzy M

    2015-12-01

    Parasites are considered to be an important selective force in host evolution but ecological studies of host-parasite systems are usually short-term providing only snap-shots of what may be dynamic systems. We have conducted four surveys of helminths of bank voles at three ecologically similar woodland sites in NE Poland, spaced over a period of 11 years, to assess the relative importance of temporal and spatial effects on helminth infracommunities. Some measures of infracommunity structure maintained relative stability: the rank order of prevalence and abundance of Heligmosomum mixtum, Heligmosomoides glareoli and Mastophorus muris changed little between the four surveys. Other measures changed markedly: dynamic changes were evident in Syphacia petrusewiczi which declined to local extinction, while the capillariid Aonchotheca annulosa first appeared in 2002 and then increased in prevalence and abundance over the remaining three surveys. Some species are therefore dynamic and both introductions and extinctions can be expected in ecological time. At higher taxonomic levels and for derived measures, year and host-age effects and their interactions with site are important. Our surveys emphasize that the site of capture is the major determinant of the species contributing to helminth community structure, providing some predictability in these systems.

  15. PROCEEDINGS OF THE WORKSHOP ON LHC INTERACTION REGION CORRECTION SYSTEMS

    International Nuclear Information System (INIS)

    FISCHER, W.; WEI, J.

    1999-01-01

    The Workshop on LHC Interaction Region Correction Systems was held at Brookhaven National Laboratory, Upton, New York, on 6 and 7 May 1999. It was attended by 25 participants from 5 institutions. The performance of the Large Hadron Collider (LHC) at collision energy is limited by the field quality of the interaction region quadrupoles and dipoles. In three sessions the workshop addressed the field quality of the these magnets, reviewed the principles and efficiency of global and local correction schemes and finalized a corrector layout. The session on Field Quality Issues, chaired by J. Strait (FNAL), discussed the progress made by KEK and FNAL in achieving the best possible field quality in the interaction region quadrupoles. Results of simulation studies were presented that assess the effects of magnetic field errors with simulation studies. Attention was given to the uncertainties in predicting and measuring field errors. The session on Global Correction, chaired by J.-P. Koutchouk (CERN), considered methods of reducing the nonlinear detuning or resonance driving terms in the accelerator one-turn map by either sorting or correcting. The session also discussed the crossing angle dependence of the dynamic aperture and operational experience from LEP. The session on Local Correction, chaired by T. Taylor (CERN), discussed the location, strength and effectiveness of multipole correctors in the interaction regions for both proton and heavy ion operation. Discussions were based on technical feasibility considerations and dynamic aperture requirements. The work on linear corrections in the interaction regions was reviewed

  16. Testing resiliency of hydrologic dynamics of a paired forested watershed after a hurricane in Atlantic coastal plain using long-term data

    Science.gov (United States)

    Devendra Amatya; Herbert Ssegane; Charles Andy Harrison; Carl Trettin

    2016-01-01

    Hurricanes are infrequent but influential disruptors of ecosystem processes, including streamflow and evapotranspiration dynamics in the southeastern Atlantic and Gulf coasts. However, literature on hurricane effects on long-term streamflow dynamics is lacking in this highly urbanizing region characterized by a poorly drained low-gradient forested landscape.

  17. Status epilepticus after prolonged umbilical cord occlusion is associated with greater neural injury in [corrected] fetal sheep at term-equivalent.

    Directory of Open Access Journals (Sweden)

    Paul P Drury

    Full Text Available The majority of pre-clinical studies of hypoxic-ischemic encephalopathy at term-equivalent have focused on either relatively mild insults, or on functional paradigms of cerebral ischemia or hypoxia-ischemia/hypotension. There is surprisingly little information on the responses to single, severe 'physiological' insults. In this study we examined the evolution and pattern of neural injury after prolonged umbilical cord occlusion (UCO. 36 chronically instrumented fetal sheep at 125-129 days gestational age (term = 147 days were subjected to either UCO until mean arterial pressure was < = 8 mmHg (n = 29, or sham occlusion (n = 7. Surviving fetuses were killed after 72 hours for histopathologic assessment with acid-fuchsin thionine. After UCO, 11 fetuses died with intractable hypotension and 5 ewes entered labor and were euthanized. The remaining 13 fetuses showed marked EEG suppression followed by evolving seizures starting at 5.8 (6.8 hours (median (interquartile range. 6 of 13 developed status epilepticus, which was associated with a transient secondary increase in cortical impedance (a measure of cytotoxic edema, p<0.05. All fetuses showed moderate to severe neuronal loss in the hippocampus and the basal ganglia but mild cortical cell loss (p<0.05 vs sham occlusion. Status epilepticus was associated with more severe terminal hypotension (p<0.05 and subsequently, greater neuronal loss (p<0.05. In conclusion, profound UCO in term-equivalent fetal sheep was associated with delayed seizures, secondary cytotoxic edema, and subcortical injury, consistent with the predominant pattern after peripartum sentinel events at term. It is unclear whether status epilepticus exacerbated cortical injury or was simply a reflection of a longer duration of asphyxia.

  18. Chernobyl radiocesium in freshwater fish: Long-term dynamics and sources of variation

    Energy Technology Data Exchange (ETDEWEB)

    Sundbom, M [Uppsala Univ., Dept. of Limnology, Uppsala (Sweden)

    2002-04-01

    The aim of this thesis was to investigate both the long-term temporal pattern and sources of individual variation for radiocesium in freshwater fish. The basis for the study is time series of {sup 137}Cs activity concentrations in fish from three lakes in the area North-west of Uppsala, Sweden that received considerable amounts of {sup 137}Cs from Chernobyl in may 1986. The lakes were Lake Ekholmssjoen, Lake Flatsjoen and Lake Siggeforasjoen, all small forest lakes, but with different morphometrical and chemical characteristics. The data were collected regularly, usually several times per year, during 1986-2000, using consistent methods. More than 7600 fish individuals from 7 species covering wide size ranges and feeding habits were analysed for {sup 137}Cs. For each fish was the length, weight, sex, and often the stomach contend recorded. The evaluation on long-term trends were based on data from all three lakes, while the study on sources of variation evaluated data from Lake Flatsjoen only. (au)

  19. Chernobyl radiocesium in freshwater fish: Long-term dynamics and sources of variation

    International Nuclear Information System (INIS)

    Sundbom, M.

    2002-01-01

    The aim of this thesis was to investigate both the long-term temporal pattern and sources of individual variation for radiocesium in freshwater fish. The basis for the study is time series of 137 Cs activity concentrations in fish from three lakes in the area North-west of Uppsala, Sweden that received considerable amounts of 137 Cs from Chernobyl in may 1986. The lakes were Lake Ekholmssjoen, Lake Flatsjoen and Lake Siggeforasjoen, all small forest lakes, but with different morphometrical and chemical characteristics. The data were collected regularly, usually several times per year, during 1986-2000, using consistent methods. More than 7600 fish individuals from 7 species covering wide size ranges and feeding habits were analysed for 137 Cs. For each fish was the length, weight, sex, and often the stomach contend recorded. The evaluation on long-term trends were based on data from all three lakes, while the study on sources of variation evaluated data from Lake Flatsjoen only. (au)

  20. Functional hoarseness in children: short-term play therapy with family dynamic counseling as therapy of choice.

    Science.gov (United States)

    Kollbrunner, Jürg; Seifert, Eberhard

    2013-09-01

    Children with nonorganic voice disorders (NVDs) are treated mainly using direct voice therapy techniques such as the accent method or glottal attack changes and indirect methods such as vocal hygiene and voice education. However, both approaches tackle only the symptoms and not etiological factors in the family dynamics and therefore often enjoy little success. The aim of the "Bernese Brief Dynamic Intervention" (BBDI) for children with NVD was to extend the effectiveness of pediatric voice therapies with a psychosomatic concept combining short-term play therapy with the child and family dynamic counseling of the parents. This study compares the therapeutic changes in three groups where different procedures were used, before intervention and 1 year afterward: counseling of parents (one to two consultations; n = 24), Brief Dynamic Intervention on the lines of the BBDI (three to five play therapy sessions with the child plus two to four sessions with the parents; n = 20), and traditional voice therapy (n = 22). A Voice Questionnaire for Parents developed by us with 59 questions to be answered on a four-point Likert scale was used to measure the change. According to the parents' assessment, a significant improvement in voice quality was achieved in all three methods. Counseling of parents (A) appears to have led parents to give their child more latitude, for example, they stopped nagging the child or demanding that he/she should behave strictly by the rules. After BBDI (B), the mothers were more responsive to their children's wishes and the children were more relaxed and their speech became livelier. At home, they called out to them less often at a distance, which probably improved parent-child dialog. Traditional voice therapy (C) seems to have had a positive effect on the children's social competence. BBDI seems to have the deepest, widest, and therefore probably the most enduring therapeutic effect on children with NVD. Copyright © 2013 The Voice Foundation

  1. Reduced short term adaptation to robot generated dynamic environment in children affected by Cerebral Palsy.

    Science.gov (United States)

    Masia, Lorenzo; Frascarelli, Flaminia; Morasso, Pietro; Di Rosa, Giuseppe; Petrarca, Maurizio; Castelli, Enrico; Cappa, Paolo

    2011-05-21

    It is known that healthy adults can quickly adapt to a novel dynamic environment, generated by a robotic manipulandum as a structured disturbing force field. We suggest that it may be of clinical interest to evaluate to which extent this kind of motor learning capability is impaired in children affected by cerebal palsy. We adapted the protocol already used with adults, which employs a velocity dependant viscous field, and compared the performance of a group of subjects affected by Cerebral Palsy (CP group, 7 subjects) with a Control group of unimpaired age-matched children. The protocol included a familiarization phase (FA), during which no force was applied, a force field adaptation phase (CF), and a wash-out phase (WO) in which the field was removed. During the CF phase the field was shut down in a number of randomly selected "catch" trials, which were used in order to evaluate the "learning index" for each single subject and the two groups. Lateral deviation, speed and acceleration peaks and average speed were evaluated for each trajectory; a directional analysis was performed in order to inspect the role of the limb's inertial anisotropy in the different experimental phases. During the FA phase the movements of the CP subjects were more curved, displaying greater and variable directional error; over the course of the CF phase both groups showed a decreasing trend in the lateral error and an after-effect at the beginning of the wash-out, but the CP group had a non significant adaptation rate and a lower learning index, suggesting that CP subjects have reduced ability to learn to compensate external force. Moreover, a directional analysis of trajectories confirms that the control group is able to better predict the force field by tuning the kinematic features of the movements along different directions in order to account for the inertial anisotropy of arm. Spatial abnormalities in children affected by cerebral palsy may be related not only to disturbance in

  2. Reduced short term adaptation to robot generated dynamic environment in children affected by Cerebral Palsy

    Directory of Open Access Journals (Sweden)

    Di Rosa Giuseppe

    2011-05-01

    Full Text Available Abstract Background It is known that healthy adults can quickly adapt to a novel dynamic environment, generated by a robotic manipulandum as a structured disturbing force field. We suggest that it may be of clinical interest to evaluate to which extent this kind of motor learning capability is impaired in children affected by cerebal palsy. Methods We adapted the protocol already used with adults, which employs a velocity dependant viscous field, and compared the performance of a group of subjects affected by Cerebral Palsy (CP group, 7 subjects with a Control group of unimpaired age-matched children. The protocol included a familiarization phase (FA, during which no force was applied, a force field adaptation phase (CF, and a wash-out phase (WO in which the field was removed. During the CF phase the field was shut down in a number of randomly selected "catch" trials, which were used in order to evaluate the "learning index" for each single subject and the two groups. Lateral deviation, speed and acceleration peaks and average speed were evaluated for each trajectory; a directional analysis was performed in order to inspect the role of the limb's inertial anisotropy in the different experimental phases. Results During the FA phase the movements of the CP subjects were more curved, displaying greater and variable directional error; over the course of the CF phase both groups showed a decreasing trend in the lateral error and an after-effect at the beginning of the wash-out, but the CP group had a non significant adaptation rate and a lower learning index, suggesting that CP subjects have reduced ability to learn to compensate external force. Moreover, a directional analysis of trajectories confirms that the control group is able to better predict the force field by tuning the kinematic features of the movements along different directions in order to account for the inertial anisotropy of arm. Conclusions Spatial abnormalities in children affected

  3. Forward induction reasoning and correct beliefs

    NARCIS (Netherlands)

    Perea y Monsuwé, Andrés

    2017-01-01

    All equilibrium concepts implicitly make a correct beliefs assumption, stating that a player believes that his opponents are correct about his first-order beliefs. In this paper we show that in many dynamic games of interest, this correct beliefs assumption may be incompatible with a very basic form

  4. The Correction of a Secondary Bilateral Cleft Lip Nasal Deformity Using Refined Open Rhinoplasty with Reverse-U Incision, V-Y Plasty, and Selective Combination with Composite Grafting: Long-term Results

    Directory of Open Access Journals (Sweden)

    Byung Chae Cho

    2012-05-01

    Full Text Available Background This article presents long-term outcomes after correcting secondary bilateralcleft lip nasal deformities using a refined reverse-U incision and V-Y plasty or in combinationwith a composite graft in order to elongate the short columella.Methods A total of forty-six patients underwent surgery between September 1996 andDecember 2008. The age of the patients ranged from 3 to 19 years of age. A bilateral reverse-Uincision and V-Y plasty were used in 24 patients. A composite graft from the helical rootwas combined with a bilateral reverse-U incision in the 22 patients who possessed a severelyshortened columella. The follow-up period ranged between 2 and 10 years.Results A total of 32 patients out of 46 were evaluated postoperatively. The average columellalength was significantly improved from an average of 3.7 mm preoperatively to 8.5 mmpostoperatively. The average ratio of the columella height to the alar base width was 0.18preoperatively and 0.29 postoperatively. The postoperative basal and lateral views revealed abetter shape of the nostrils and columella. The elongated columella, combined with a compositegraft, presented good maintenance of the corrected position with no growth disturbance. Acomposite graft showed color mismatching in several patients. Twenty-six patients demonstratedno alar-columella web deformity and satisfactory symmetry of the nostrils. Four patientsexperienced a drooping and overhanging of the corrected alar-columella web.Conclusions A bilateral reverse-U incision with V-Y plasty or in combination with acomposite graft was effective in correcting secondary bilateral cleft lip nasal deformity.

  5. The Correction of a Secondary Bilateral Cleft Lip Nasal Deformity Using Refined Open Rhinoplasty with Reverse-U Incision, V-Y Plasty, and Selective Combination with Composite Grafting: Long-term Results

    Directory of Open Access Journals (Sweden)

    Byung Chae Cho

    2012-05-01

    Full Text Available BackgroundThis article presents long-term outcomes after correcting secondary bilateral cleft lip nasal deformities using a refined reverse-U incision and V-Y plasty or in combination with a composite graft in order to elongate the short columella.MethodsA total of forty-six patients underwent surgery between September 1996 and December 2008. The age of the patients ranged from 3 to 19 years of age. A bilateral reverse-U incision and V-Y plasty were used in 24 patients. A composite graft from the helical root was combined with a bilateral reverse-U incision in the 22 patients who possessed a severely shortened columella. The follow-up period ranged between 2 and 10 years.ResultsA total of 32 patients out of 46 were evaluated postoperatively. The average columella length was significantly improved from an average of 3.7 mm preoperatively to 8.5 mm postoperatively. The average ratio of the columella height to the alar base width was 0.18 preoperatively and 0.29 postoperatively. The postoperative basal and lateral views revealed a better shape of the nostrils and columella. The elongated columella, combined with a composite graft, presented good maintenance of the corrected position with no growth disturbance. A composite graft showed color mismatching in several patients. Twenty-six patients demonstrated no alar-columella web deformity and satisfactory symmetry of the nostrils. Four patients experienced a drooping and overhanging of the corrected alar-columella web.ConclusionsA bilateral reverse-U incision with V-Y plasty or in combination with a composite graft was effective in correcting secondary bilateral cleft lip nasal deformity.

  6. The role of reconsolidation and the dynamic process of long-term memory formation and storage

    Directory of Open Access Journals (Sweden)

    Cristina M Alberini

    2011-03-01

    Full Text Available It is becoming increasingly clear that the processes of memory formation and storage are exquisitely dynamic. Elucidating the nature and temporal evolution of the biological changes that accompany encoding, storage and retrieval is key to understand memory formation. For explicit or medial temporal lobe-dependent memories that form after a discrete event and are stored for a long time, the physical changes underlying the encoding and processing of the information (memory trace or engram remain in a fragile state for some time. However, over time, the new memory becomes increasingly resistant to disruption until it is consolidated. Retrieval or reactivation of an apparently consolidated memory can render the memory labile again, and reconsolidation is the process that occurs to mediate its restabilization. Reconsolidation also evolves with the age of the memory: Young memories are sensitive to postreactivation disruption, but older memories are more resistant. Why does a memory become labile again if it is retrieved or reactivated? Here I suggest that the main function of reconsolidation is to contribute to the lingering consolidation process and mediate memory strengthening. I also discuss the literature and results regarding the influence of the passage of time on the reconsolidation of memory. These points have important implications for the use of reconsolidation in therapeutic settings.

  7. Difference between the vocalizations of two sister species of pigeons explained in dynamical terms.

    Science.gov (United States)

    Alonso, R Gogui; Kopuchian, Cecilia; Amador, Ana; Suarez, Maria de Los Angeles; Tubaro, Pablo L; Mindlin, Gabriel B

    2016-05-01

    Vocal communication is an unique example, where the nonlinear nature of the periphery can give rise to complex sounds even when driven by simple neural instructions. In this work we studied the case of two close-related bird species, Patagioenas maculosa and Patagioenas picazuro, whose vocalizations differ only in the timbre. The temporal modulation of the fundamental frequency is similar in both cases, differing only in the existence of sidebands around the fundamental frequency in the P. maculosa. We tested the hypothesis that the qualitative difference between these vocalizations lies in the nonlinear nature of the syrinx. In particular, we propose that the roughness of maculosa's vocalizations is due to an asymmetry between the right and left vibratory membranes, whose nonlinear dynamics generate the sound. To test the hypothesis, we generated a biomechanical model for vocal production with an asymmetric parameter Q with which we can control the level of asymmetry between these membranes. Using this model we generated synthetic vocalizations with the principal acoustic features of both species. In addition, we confirmed the anatomical predictions by making post mortem inspection of the syrinxes, showing that the species with tonal song (picazuro) has a more symmetrical pair of membranes compared to maculosa.

  8. Early short-term management of control-actuator failures in a linear dynamic system

    International Nuclear Information System (INIS)

    Ben-Haim, Y.

    1989-01-01

    Early short-term management of malfunction attempts to maintain system stability during the early development stages of a failure. This is achieved in two stages. First, the failure is partially diagnosed by comparing observed system behavior against the performance expected for each of the selected set of hypothesized malfunctions. Second, the normal controller is replaced by a compensatory controller whose aim is to maintain system stability while compensating for the failure. Malfunctions involving control actuators are studied here. The aim of this study is to develop a technique for choosing the set of hypothesized failures and compensatory controllers which assure that the state of the system remains within specified bounds for a given duration after initiation of failure, regardless of the precise temporal development of the failure

  9. Lagoon Sediment Dynamics: A Coupled Model to Study a Medium-Term Silting of Tidal Channels

    Directory of Open Access Journals (Sweden)

    Marco Petti

    2018-04-01

    Full Text Available The silting of tidal channels is a natural process that affects several shallow lagoons and makes it difficult to navigate, requiring regular maintenance interventions. This phenomenon is the result of the complex non-linear interaction between tidal currents and wave motion. In this work, the morphodynamic evolution of the Marano and Grado lagoon is investigated by means of a two-dimensional horizontal (2DH morphological-hydrodynamic and a spectral coupled model. An innovative procedure to reproduce the overall bathymetric changes in the medium term and, in particular, the volumes deposited inside channels, is presented. An average year with a sequence of winds and tides acting over that time was reconstructed, carrying out cross correlation techniques and spectral analyses of measured data. The predicted morphological evolution matches the annual dredged volumes in the lagoon critical branches and shows the distribution of erosion and deposition of cohesive sediments according to spatially variable values of critical shear stress.

  10. Assessment of dynamic and long-term performance of an innovative multi-story timber building via structural monitoring and dynamic testing

    Science.gov (United States)

    Omenzetter, Piotr; Morris, Hugh; Worth, Margaret; Gaul, Andrew; Jager, Simon; Desgeorges, Yohann

    2012-04-01

    An innovative three-story timber building, using self-centering, post-tensioned timber shear walls as the main horizontal load resisting system and lightweight non-composite timber-concrete floors, has recently been completed in Nelson, New Zealand. It is expected to be the trailblazer for similar but taller structures to be more widely adopted. Performance based standards require an advanced understanding of building responses and in order to meet the need for in-situ performance data the building has been subjected to forced vibration testing and instrumented for continuous monitoring using a total of approximately 90 data channels to capture its dynamic and long-term responses. The first part of the paper presents a brief discussion of the existing research on the seismic performance of timber frame buildings and footfall induced floor vibrations. An outline of the building structural system, focusing on the novel design solutions, is then discussed. This is followed by the description of the monitoring system. The analysis of monitoring results starts with a discussion of the monitoring of long-term deformations. Next, the assessment of the floor vibration serviceability performance is outlined. Then, the forced vibration tests conducted on the whole building at different construction stages are reviewed. The system identification results from seismic shaking records are also discussed. Finally, updating of a finite element model of the building is conducted.

  11. Implantable fiber-optic interface for parallel multisite long-term optical dynamic brain interrogation in freely moving mice

    Science.gov (United States)

    Doronina-Amitonova, L. V.; Fedotov, I. V.; Ivashkina, O. I.; Zots, M. A.; Fedotov, A. B.; Anokhin, K. V.; Zheltikov, A. M.

    2013-01-01

    Seeing the big picture of functional responses within large neural networks in a freely functioning brain is crucial for understanding the cellular mechanisms behind the higher nervous activity, including the most complex brain functions, such as cognition and memory. As a breakthrough toward meeting this challenge, implantable fiber-optic interfaces integrating advanced optogenetic technologies and cutting-edge fiber-optic solutions have been demonstrated, enabling a long-term optogenetic manipulation of neural circuits in freely moving mice. Here, we show that a specifically designed implantable fiber-optic interface provides a powerful tool for parallel long-term optical interrogation of distinctly separate, functionally different sites in the brain of freely moving mice. This interface allows the same groups of neurons lying deeply in the brain of a freely behaving mouse to be reproducibly accessed and optically interrogated over many weeks, providing a long-term dynamic detection of genome activity in response to a broad variety of pharmacological and physiological stimuli. PMID:24253232

  12. Statistical modeling of the Internet traffic dynamics: To which extent do we need long-term correlations?

    Science.gov (United States)

    Markelov, Oleg; Nguyen Duc, Viet; Bogachev, Mikhail

    2017-11-01

    Recently we have suggested a universal superstatistical model of user access patterns and aggregated network traffic. The model takes into account the irregular character of end user access patterns on the web via the non-exponential distributions of the local access rates, but neglects the long-term correlations between these rates. While the model is accurate for quasi-stationary traffic records, its performance under highly variable and especially non-stationary access dynamics remains questionable. In this paper, using an example of the traffic patterns from a highly loaded network cluster hosting the website of the 1998 FIFA World Cup, we suggest a generalization of the previously suggested superstatistical model by introducing long-term correlations between access rates. Using queueing system simulations, we show explicitly that this generalization is essential for modeling network nodes with highly non-stationary access patterns, where neglecting long-term correlations leads to the underestimation of the empirical average sojourn time by several decades under high throughput utilization.

  13. Impact of surgical correction of tetralogy of fallot on short-term right and left ventricular function as determined by 2-dimensional speckle tracking echocardiography

    Science.gov (United States)

    Li, Yuman; Wang, Xinfang; Lv, Qing; Wang, Jing; Yang, YaLi; He, Lin; Yuan, Li; Zhang, Li; Xie, Mingxing

    2016-01-01

    Abstract Right ventricular (RV) and left ventricular (LV) dysfunction is an important determinant of poor clinical status in repaired patients with tetralogy of Fallot (TOF). The purpose of our study is to assess the impact of surgical repair on short-term RV and LV function by 2-dimensional speckle tracking echocardiography (STE). Sixty-seven patients (median age 12 months) with TOF before and 6 months after repair and 35 healthy subjects were studied. The patients were divided into the younger (age at surgery ≤12 months) and older (age at surgery >12 months) subgroups. RV and LV global longitudinal systolic strain and strain rate (SR), and LV global circumferential and radial systolic strain and SR were measured by STE. After repair, RV longitudinal strain and SR increased in the younger patients, whereas RV longitudinal SR was decreased in the older patients. LV deformation parameters were unchanged in all patients. In the multivariate analysis, patients with better RV and LV deformation parameters preoperatively were identified to have better RV and LV strain and SR postoperatively (P < 0.05 for all). The surgical approach of the pulmonary valve ring was predictive of RV and LV systolic function postoperatively (P < 0.05 for all). After TOF repair, short-term RV function improvement is identified in the younger but not in the older patients, whereas LV function is unchanged in all patients. The preoperative RV and LV deformational indices are the determinant of postoperative biventricular function improvement. STE appears to be a valuable tool for assessment of biventricular function after congenital heart disease surgery. PMID:27495064

  14. Long-term tritium monitoring to study river basin dynamics: case of the Danube River basin

    Science.gov (United States)

    Aggarwal, Pradeep; Araguas, Luis; Groening, Manfred; Newman, Brent; Kurttas, Turker; Papesch, Wolfgang; Rank, Dieter; Suckow, Axel; Vitvar, Tomas

    2010-05-01

    During the last five decades, isotope concentrations (O-18, D, tritium) have been extensively measured in precipitation, surface- and ground-waters to derive information on residence times of water in aquifers and rivers, recharge processes, and groundwater dynamics. The unique properties of the isotopes of the water molecule as tracers are especially useful for understanding the retention of water in river basins, which is a key parameter for assessing water resources availability, addressing quality issues, investigating interconnections between surface- and ground-waters, and for predicting possible hydrological shifts related to human activities and climate change. Detailed information of the spatial and temporal changes of isotope contents in precipitation at a global scale was one of the initial aims of the Global Network of Isotopes in Precipitation (GNIP), which has provided a detailed chronicle of tritium and stable isotope contents in precipitation since the 1960s. Accurate information of tritium contents resulting of the thermonuclear atmospheric tests in the 1950s and 1960s is available in GNIP for stations distributed world-wide. Use of this dataset for hydrological dating or as an indicator of recent recharge has been extensive in shallow groundwaters. However, its use has been more limited in surface waters, due to the absence of specific monitoring programmes of tritium and stable isotopes in rivers, lakes and other surface water bodies. The IAEA has recently been compiling new and archival isotope data measured in groundwaters, rivers, lakes and other water bodies as part of its web based Water Isotope System for Data Analysis, Visualization and Electronic Retrieval (WISER). Recent additions to the Global Network of Isotopes in Rivers (GNIR) contained within WISER now make detailed studies in rivers possible. For this study, we are re-examining residence time estimates for the Danube in central Europe. Tritium data are available in GNIR from 15

  15. Dynamics of short-term acclimation to UV radiation in marine diatoms.

    Science.gov (United States)

    Fouqueray, Manuela; Mouget, Jean-Luc; Morant-Manceau, Annick; Tremblin, Gérard

    2007-11-12

    In order to investigate the dynamics of the acclimation of marine diatoms to ultraviolet radiation (UVR), Amphora coffeaeformis, Odontella aurita and Skeletonema costatum were exposed for 5 h per day to a combination of UVA and UVB (UVBR/UVAR ratio 4.5%) with a total UVR daily dose of 110 kJ m(-2), which is equivalent to that observed in the natural environment. This treatment was applied in the middle of the photoperiod and was repeated on five successive days. During the UVR treatment, chlorophyll fluorescence parameters were monitored, damage and repair constants were calculated from effective quantum yield values (phi(PSII)), and rapid light curves (electron transport rate versus irradiance curves using short light steps of different intensity) were plotted to determine the maximum relative electron transport rate (rETR(max)) and maximum light use efficiency (alpha). In all species the growth rate was lower than control from day 1-3, but increased thereafter, except for S. costatum. The cellular chlorophyll a content increased significantly with repeated daily exposure to UVR for A. coffeaeformis only. In all species, the fluorescence parameters (F(m), the maximum fluorescence level measured in the dark, phi(PSII), rETR(max) and alpha) decreased during UVR exposure, in contrast to F(0) (the minimum fluorescence level measured in the dark). The response to UVR stress was species-specific. S. costatum was very sensitive, and failed to survive for more than three days, whereas A. coffeaeformis and O. aurita were able to acclimate to UVR stress. These two species used different strategies. In A. coffeaeformis, the repair constant was lower than the damage constant, but phi(PSII) values returned to baseline values at the beginning of each experimental day, indicating that an effective active recovery process occurred after stress. In O. aurita, the repair processes took place during the stress, and could account for the UVR tolerance of this species.

  16. Distinguishing patterns in the dynamics of long-term medication use by Markov analysis: beyond persistence

    Directory of Open Access Journals (Sweden)

    Lammers Jan-Willem J

    2007-07-01

    Full Text Available Abstract Background In order to accurately distinguish gaps of varying length in drug treatment for chronic conditions from discontinuation without resuming therapy, short-term observation does not suffice. Thus, the use of inhalation corticosteroids (ICS in the long-term, during a ten-year period is investigated. To describe medication use as a continuum, taking into account the timeliness and consistency of refilling, a Markov model is proposed. Methods Patients, that filled at least one prescription in 1993, were selected from the PHARMO medical record linkage system (RLS containing >95% prescription dispensings per patient originating from community pharmacy records of 6 medium-sized cities in the Netherlands. The probabilities of continuous use, the refilling of at least one ICS prescription in each year of follow-up, and medication free periods were assessed by Markov analysis. Stratified analysis according to new use was performed. Results The transition probabilities of the refilling of at least one ICS prescription in the subsequent year of follow-up, were assessed for each year of follow-up and for the total study period. The change of transition probabilities in time was evaluated, e.g. the probability of continuing ICS use of starters in the first two years (51% of follow-up increased to more than 70% in the following years. The probabilities of different patterns of medication use were assessed: continuous use (7.7%, cumulative medication gaps (1–8 years 69.1% and discontinuing (23.2% during ten-year follow-up for new users. New users had lower probability of continuous use (7.7% and more variability in ICS refill patterns than previous users (56%. Conclusion In addition to well-established methods in epidemiology to ascertain compliance and persistence, a Markov model could be useful to further specify the variety of possible patterns of medication use within the continuum of adherence. This Markov model describes variation in

  17. The long-term impact of urbanization on nitrogen patterns and dynamics in Shanghai, China

    International Nuclear Information System (INIS)

    Gu Baojing; Dong Xiaoli; Peng Changhui; Luo Weidong; Chang Jie; Ge Ying

    2012-01-01

    Urbanization is an important process that alters the regional and global nitrogen biogeochemistry. In this study, we test how long-term urbanization (1952–2004) affects the nitrogen flows, emissions and drivers in the Greater Shanghai Area (GSA) based on the coupled human and natural systems (CHANS) approach. Results show that: (1) total nitrogen input to the GSA increased from 57.7 to 587.9 Gg N yr −1 during the period 1952–2004, mainly attributing to fossil fuel combustion (43%), Haber–Bosch nitrogen fixation (31%), and food/feed import (26%); (2) per capita nitrogen input increased from 13.5 to 45.7 kg N yr −1 , while per gross domestic product (GDP) nitrogen input reduced from 22.2 to 0.9 g N per Chinese Yuan, decoupling of nitrogen with GDP; (3) emissions of reactive nitrogen to the environment transformed from agriculture dominated to industry and human living dominated, especially for air pollution. This study provides decision-makers a novel view of nitrogen management. - Highlights: ► Major Nr emission source shifts from agriculture to industry alongside urbanization. ► Decoupling of nitrogen with GDP and urban expansion arises alongside urbanization. ► Nitrogen fluxes increase with population growth and living standard promotion. - Major nitrogen emission source shifts from agriculture to industry and human, and decoupling of nitrogen with GDP and urban expansion arises alongside urbanization.

  18. Locating Temporal Functional Dynamics of Visual Short-Term Memory Binding using Graph Modular Dirichlet Energy

    Science.gov (United States)

    Smith, Keith; Ricaud, Benjamin; Shahid, Nauman; Rhodes, Stephen; Starr, John M.; Ibáñez, Augustin; Parra, Mario A.; Escudero, Javier; Vandergheynst, Pierre

    2017-02-01

    Visual short-term memory binding tasks are a promising early marker for Alzheimer’s disease (AD). To uncover functional deficits of AD in these tasks it is meaningful to first study unimpaired brain function. Electroencephalogram recordings were obtained from encoding and maintenance periods of tasks performed by healthy young volunteers. We probe the task’s transient physiological underpinnings by contrasting shape only (Shape) and shape-colour binding (Bind) conditions, displayed in the left and right sides of the screen, separately. Particularly, we introduce and implement a novel technique named Modular Dirichlet Energy (MDE) which allows robust and flexible analysis of the functional network with unprecedented temporal precision. We find that connectivity in the Bind condition is less integrated with the global network than in the Shape condition in occipital and frontal modules during the encoding period of the right screen condition. Using MDE we are able to discern driving effects in the occipital module between 100-140 ms, coinciding with the P100 visually evoked potential, followed by a driving effect in the frontal module between 140-180 ms, suggesting that the differences found constitute an information processing difference between these modules. This provides temporally precise information over a heterogeneous population in promising tasks for the detection of AD.

  19. The long-term impact of urbanization on nitrogen patterns and dynamics in Shanghai, China.

    Science.gov (United States)

    Gu, Baojing; Dong, Xiaoli; Peng, Changhui; Luo, Weidong; Chang, Jie; Ge, Ying

    2012-12-01

    Urbanization is an important process that alters the regional and global nitrogen biogeochemistry. In this study, we test how long-term urbanization (1952-2004) affects the nitrogen flows, emissions and drivers in the Greater Shanghai Area (GSA) based on the coupled human and natural systems (CHANS) approach. Results show that: (1) total nitrogen input to the GSA increased from 57.7 to 587.9 Gg N yr(-1) during the period 1952-2004, mainly attributing to fossil fuel combustion (43%), Haber-Bosch nitrogen fixation (31%), and food/feed import (26%); (2) per capita nitrogen input increased from 13.5 to 45.7 kg N yr(-1), while per gross domestic product (GDP) nitrogen input reduced from 22.2 to 0.9 g N per Chinese Yuan, decoupling of nitrogen with GDP; (3) emissions of reactive nitrogen to the environment transformed from agriculture dominated to industry and human living dominated, especially for air pollution. This study provides decision-makers a novel view of nitrogen management. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Short-term dynamics of culturable bacteria in a soil amended with biotransformed dry olive residue.

    Science.gov (United States)

    Siles, J A; Pascual, J; González-Menéndez, V; Sampedro, I; García-Romera, I; Bills, G F

    2014-03-01

    Dry olive residue (DOR) transformation by wood decomposing basidiomycetes (e.g. Coriolopsis floccosa) is a possible strategy for eliminating the liabilities related to the use of olive oil industry waste as an organic soil amendment. The effects of organic fertilization with DOR on the culturable soil microbiota are largely unknown. Therefore, the objectives of this study were to measure the short-term effects of DOR and C. floccosa-transformed DOR on the culturable bacterial soil community, while at the same time documenting the bacterial diversity of an agronomic soil in the southeastern Iberian Peninsula. The control soil was compared with the same soil treated with DOR and with C. floccosa-transformed DOR for 0, 30 and 60 days. Impact was measured from total viable cells and CFU counts, as well as the isolation and characterization of 900 strains by fatty acid methyl ester profiles and 16S rRNA partial sequencing. The bacterial diversity was distributed between Actinobacteria, Alphaproteobacteria, Gammaproteobacteria, Betaproteobacteria, Bacilli, Sphingobacteria and Cytophagia. Analysis of the treatments and controls demonstrated that soil amendment with untransformed DOR produced important changes in bacterial density and diversity. However, when C. floccosa-transformed DOR was applied, bacterial proliferation was observed but bacterial diversity was less affected, and the distribution of microorganisms was more similar to the unamended soil. Copyright © 2013 Elsevier GmbH. All rights reserved.

  1. Short-Term Dynamics of Behavioral Thermoregulation by Adults of the Grasshopper Melanoplus sanguinipes

    Science.gov (United States)

    O'Neill, Kevin M.; Rolston, Marni G.

    2007-01-01

    The short-term behavioral responses of adult grasshoppers, Melanoplus sanguinipes (F.) (Orthoptera: Acrididae), were examined after they experienced changes in microclimate when beingforced to change positions in their habitat. It was also determined if and when behavioral tactics allowed adults to achieve body temperatures within their preferred range. The preferred or set-point range, here taken as the interquartile range of temperatures selected on a laboratory thermal gradient, was estimated to be 37.4–40.5°C. In the field, adults progressed through a relatively consistent daily sequence of behaviors, basking on the soil early in the day, but moving onto vegetation as temperatures increased. Although basking allowed grasshoppers to maximize body temperature within the available range, as much as 7°C in excess of air temperature, they could not attain preferred body temperatures until soil surface temperatures reach about 35°C. Basking was more effective in grazed than ungrazed pastures due to a lower degree of shading of the soil surface. As soil surface temperatures exceeded 35°C, grasshoppers could achieve body temperatures within the preferred range by moving to the appropriate height on vegetation. These results illustrate the advantage of assessing behavior in the field in relation to preferred body temperatures determined in the laboratory. PMID:20302531

  2. Iron oxides dynamics in a subtropical Brazilian Paleudult under long-term no-tillage management

    Directory of Open Access Journals (Sweden)

    Alberto Vasconcellos Inda

    2013-02-01

    Full Text Available Replacing conventional tillage (CT with no-tillage (NT management alters the pedoenvironment and the rate of topsoil processes, with possible effects on dissolution processes associated with iron oxides and therefore soil mineralogy. This study aimed to determine the effect of NT on the content and distribution of types of iron oxides in a Rhodic Paleudult in southern Brazil. Soil samples were collected at eight depths within the 0.00-0.80 m layer under CT and NT in a long-term experiment (21 years. Mineralogical identification was conducted by X-ray diffraction (XRD, and the Fe content related to specific types of iron oxides determined by selective dissolution and diffuse-reflectance spectroscopy. Kaolinite, quartz, goethite, hematite, and maghemite were identified in the clay fraction. In the NT-managed soil, there was a decrease in the content of crystalline iron oxides and an increase in the content of poorly crystalline iron oxides with increasing proximity to the soil surface. These results suggest that iron oxides are rearranged in this soil by reductive dissolution of the crystalline types and neoformation of metastable ferrihydrite in topsoil layers, which should be assessed further in laboratory studies.

  3. From pre-storm activity to magnetic storms: a transition described in terms of fractal dynamics

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    G. Balasis

    2006-12-01

    Full Text Available We show that distinct changes in scaling parameters of the Dst index time series occur as an intense magnetic storm approaches, revealing a gradual reduction in complexity. The remarkable acceleration of energy release – manifested in the increase in susceptibility – couples to the transition from anti-persistent (negative feedback to persistent (positive feedback behavior and indicates that the occurence of an intense magnetic storm is imminent. The main driver of the Dst index, the VBSouth electric field component, does not reveal a similar transition to persistency prior to the storm. This indicates that while the magnetosphere is mostly driven by the solar wind the critical feature of persistency in the magnetosphere is the result of a combination of solar wind and internal magnetospheric activity rather than solar wind variations alone. Our results suggest that the development of an intense magnetic storm can be studied in terms of "intermittent criticality" that is of a more general character than the classical self-organized criticality phenomena, implying the predictability of the magnetosphere.

  4. Binding neutral information to emotional contexts: Brain dynamics of long-term recognition memory.

    Science.gov (United States)

    Ventura-Bort, Carlos; Löw, Andreas; Wendt, Julia; Moltó, Javier; Poy, Rosario; Dolcos, Florin; Hamm, Alfons O; Weymar, Mathias

    2016-04-01

    There is abundant evidence in memory research that emotional stimuli are better remembered than neutral stimuli. However, effects of an emotionally charged context on memory for associated neutral elements is also important, particularly in trauma and stress-related disorders, where strong memories are often activated by neutral cues due to their emotional associations. In the present study, we used event-related potentials (ERPs) to investigate long-term recognition memory (1-week delay) for neutral objects that had been paired with emotionally arousing or neutral scenes during encoding. Context effects were clearly evident in the ERPs: An early frontal ERP old/new difference (300-500 ms) was enhanced for objects encoded in unpleasant compared to pleasant and neutral contexts; and a late central-parietal old/new difference (400-700 ms) was observed for objects paired with both pleasant and unpleasant contexts but not for items paired with neutral backgrounds. Interestingly, objects encoded in emotional contexts (and novel objects) also prompted an enhanced frontal early (180-220 ms) positivity compared to objects paired with neutral scenes indicating early perceptual significance. The present data suggest that emotional--particularly unpleasant--backgrounds strengthen memory for items encountered within these contexts and engage automatic and explicit recognition processes. These results could help in understanding binding mechanisms involved in the activation of trauma-related memories by neutral cues.

  5. Declines revisited: Long-term recovery and spatial population dynamics oftailed frog larvae after wildfire

    Science.gov (United States)

    Hossack, Blake R.; Honeycutt, Richard

    2017-01-01

    Drought has fueled an increased frequency and severity of large wildfires in many ecosystems. Despite an increase in research on wildfire effects on vertebrates, the vast majority of it has focused on short-term (effects and there is still little information on the time scale of population recovery for species that decline in abundance after fire. In 2003, a large wildfire in Montana (USA) burned the watersheds of four of eight streams that we sampled for larval Rocky Mountain tailed frogs (Ascaphus montanus) in 2001. Surveys during 2004–2005 revealed reduced abundance of larvae in burned streams relative to unburned streams, with greater declines associated with increased fire extent. Rocky Mountain tailed frogs have low vagility and have several unusual life-history traits that could slow population recovery, including an extended larval period (4 years), delayed sexual maturity (6–8 years), and low fecundity (negative effects of burn extent on larval abundance weakened> 58% within 12 years after the fire. We also found moderate synchrony among populations in unburned streams and negative spatial autocorrelation among populations in burned streams. We suspect negative spatial autocorrelation among spatially-clustered burned streams reflected increased post-fire patchiness in resources and different rates of local recovery. Our results add to a growing body of work that suggests populations in intact ecosystems tend to be resilient to habitat changes caused by wildfire. Our results also provide important insights into recovery times of populations that have been negatively affected by severe wildfire.

  6. Proteome dynamics and physiological responses to short-term salt stress in Leymus chinensis leaves.

    Directory of Open Access Journals (Sweden)

    Jikai Li

    Full Text Available Salt stress is becoming an increasing threat to global agriculture. In this study, physiological and proteomics analysis were performed using a salt-tolerant grass species, Leymus chinensis (L. chinensis. The aim of this study is to understand the potential mechanism of salt tolerance in L. chinensis that used for crop molecular breeding. A series of short-term (<48 h NaCl treatments (0 ~ 700 mM were conducted. Physiological data indicated that the root and leaves growth were inhibited, chlorophyll contents decreased, while hydraulic conductivity, proline, sugar and sucrose were accumulated under salt stress. For proteomic analysis, we obtained 274 differentially expressed proteins in response to NaCl treatments. GO analysis revealed that 44 out of 274 proteins are involved in the biosynthesis of amino acids and carbon metabolism. Our findings suggested that L. chinensis copes with salt stress by stimulating the activities of POD, SOD and CAT enzymes, speeding up the reactions of later steps of citrate cycle, and synthesis of proline and sugar. In agreement with our physiological data, proteomic analysis also showed that salt stress depress the expression of photosystem relevant proteins, Calvin cycle, and chloroplast biosynthesis.

  7. RELATIONSHIP OF LIPID PROFILE AND IMMUNE STATUS IN THE DYNAMICS OF LONG-TERM EXPOSURE TO COAL-ROCK DUST ON THE BODY (EXPERIMENTAL STUDIES

    Directory of Open Access Journals (Sweden)

    Анастасия Сергеевна Казицкая

    2017-10-01

    Full Text Available Subject. The relationship between lipid metabolism and immune reactivity in the dynamics of long-term exposure to coal-rock dust (CRD on the body. Objective. In the experiment to examine the impact of the changes in the lipid profile on immune status under the conditions of long-term exposure to CRD on the body. Methods. The experiments were carried out on 110 white male rats weighing 200-250 g. The inhalation method was used for modeling that best fits the conditions of coal-mine production. Animals were divided into 2 groups: the control (n = 30; the experiment (n = 80, that are the rats who inhaled CRD with a particle size of up to 5 microns in an average concentration of 50 mg/m3 for 4 hours daily for 12 weeks. Main results. Early terms of the CRD impact are characterized by the activation of the immune system against the background of metabolic shifts as well as by morphological changes of the immune nature in the bronchopulmonary system and liver of the rats that can be regarded as compensatory-adaptive. Prolonged exposure to the dust factor leads to an increase in dyslipidemia, which contributes to the development of immune imbalance as well as morphological changes that are indicative of the chronic inflammation and disturbance of compensatory mechanisms. Field of application. The results of the conducted experimental studies broaden the fundamental ideas about the mechanisms of immune body defense. The detection of pathogenetic mechanisms underlying the formation and course of occupational diseases allows assessing the functional state of the organism at the stage of pre-existing disease, revealing the initial signs of developing pathology and determining the ways of their correction. Conclusions. CRD intake is characterized by the development of metabolic changes, which are closely related to immune reactivity. An integrated approach to the study of occupational and industrially-caused pathology makes it possible to assess the

  8. Dynamics and cultural specifics of information needs under conditions of long-term space flight

    Science.gov (United States)

    Feichtinger, Elena; Shved, Dmitry; Gushin, Vadim

    Life in conditions of space flight or chamber study with prolonged isolation is associated with lack of familiar stimuli (sensory deprivation), monotony, significant limitation of communication, and deficit of information and media content (Myasnikov V.I., Stepanova S.I. et al., 2000). Fulfillment of a simulation experiment or flight schedule implies necessity of performance of sophisticated tasks and decision making with limited means of external support. On the other hand, the “stream” of information from the Mission Control (MC) and PI’s (reminders about different procedures to be performed, requests of reports, etc.) is often inadequate to communication needs of crewmembers. According to the theory of “information stress” (Khananashvili M.M., 1984), a distress condition could be formed if: a) it’s necessary to process large amounts of information and make decisions under time pressure; b) there is a prolonged deficit of necessary (e.g. for decision making) information. Thus, we suppose that one of the important goals of psychological support of space or space simulation crews should be forming of favorable conditions of information environment. For that purpose, means of crew-MC information exchange (quantitative characteristics and, if possible, content of radiograms, text and video messages, etc.) should be studied, as well as peculiarities of the crewmembers’ needs in different information and media content, and their reactions to incoming information. In the space simulation experiment with 520-day isolation, communication of international crew with external parties had been studied. Dynamics of quantitative and content characteristics of the crew’s messages was related to the experiment’s stage, presence of “key” events in the schedule (periods of high autonomy, simulated “planetary landing”, etc.), as well as to events not related to the experiment (holidays, news, etc.). It was shown that characteristics of information exchange

  9. Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality.

    Science.gov (United States)

    Kravchenko, Julia; Akushevich, Igor; Abernethy, Amy P; Holman, Sheila; Ross, William G; Lyerly, H Kim

    2014-01-01

    The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina was associated with reduced rates of death from respiratory diseases in local populations. We analyzed the trends of emphysema, asthma, and pneumonia mortality and changes of the levels of ozone, sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and particulate matters (PM2.5 and PM10) using monthly data measurements from air-monitoring stations in North Carolina in 1993-2010. The log-linear model was used to evaluate associations between air-pollutant levels and age-adjusted death rates (per 100,000 of population) calculated for 5-year age-groups and for standard 2000 North Carolina population. The studied associations were adjusted by age group-specific smoking prevalence and seasonal fluctuations of disease-specific respiratory deaths. Decline in emphysema deaths was associated with decreasing levels of SO2 and CO in the air, decline in asthma deaths-with lower SO2, CO, and PM10 levels, and decline in pneumonia deaths-with lower levels of SO2. Sensitivity analyses were performed to study potential effects of the change from International Classification of Diseases (ICD)-9 to ICD-10 codes, the effects of air pollutants on mortality during summer and winter, the impact of approach when only the underlying causes of deaths were used, and when mortality and air-quality data were analyzed on the county level. In each case, the results of sensitivity analyses demonstrated stability. The importance of analysis of pneumonia as an underlying cause of death was also highlighted. Significant associations were observed between decreasing death rates of emphysema, asthma, and pneumonia and decreases in levels of ambient air pollutants in North Carolina.

  10. LTS and FS inhibitory interneurons, short-term synaptic plasticity, and cortical circuit dynamics.

    Directory of Open Access Journals (Sweden)

    Itai Hayut

    2011-10-01

    Full Text Available Somatostatin-expressing, low threshold-spiking (LTS cells and fast-spiking (FS cells are two common subtypes of inhibitory neocortical interneuron. Excitatory synapses from regular-spiking (RS pyramidal neurons to LTS cells strongly facilitate when activated repetitively, whereas RS-to-FS synapses depress. This suggests that LTS neurons may be especially relevant at high rate regimes and protect cortical circuits against over-excitation and seizures. However, the inhibitory synapses from LTS cells usually depress, which may reduce their effectiveness at high rates. We ask: by which mechanisms and at what firing rates do LTS neurons control the activity of cortical circuits responding to thalamic input, and how is control by LTS neurons different from that of FS neurons? We study rate models of circuits that include RS cells and LTS and FS inhibitory cells with short-term synaptic plasticity. LTS neurons shift the RS firing-rate vs. current curve to the right at high rates and reduce its slope at low rates; the LTS effect is delayed and prolonged. FS neurons always shift the curve to the right and affect RS firing transiently. In an RS-LTS-FS network, FS neurons reach a quiescent state if they receive weak input, LTS neurons are quiescent if RS neurons receive weak input, and both FS and RS populations are active if they both receive large inputs. In general, FS neurons tend to follow the spiking of RS neurons much more closely than LTS neurons. A novel type of facilitation-induced slow oscillations is observed above the LTS firing threshold with a frequency determined by the time scale of recovery from facilitation. To conclude, contrary to earlier proposals, LTS neurons affect the transient and steady state responses of cortical circuits over a range of firing rates, not only during the high rate regime; LTS neurons protect against over-activation about as well as FS neurons.

  11. Long-term dynamics of a lake ecosystem and the implications for radiation exposure

    International Nuclear Information System (INIS)

    Sundblad, B.; Bergstroem, U.; Evan, S.; Puigdomenech, I.

    1988-09-01

    Long-term ageing and physical transformation of ecosystems may occur while a continuous leakage of radionuclides from a repository is going on. This will imply additional uncertainties as regards the consequences for exposure to man. The turnover of nuclides during the ageing of a lake ecosystem and its successive development into agricultural land is simulated using a multicompartment system. Parameters of a major importance for the distribution and reconcentration of radionuclides supplied into the lake as surface inflow are identified. Seven radioniclides occuring in high-level waste aer treated. These are I-129, Cs-135, Ra-226, Pa-231, U-234, Np-237 and Pu-239. The activity distribution is highly dependent on the sorption behaviour of the radionuclides. The major pools for radionuclide distribution are lake outflows 15-97% (Pu-239 - I-129) and deeo lake sediment 2-84% (I-129 - Pu-239). Performed dose calculations for different time periods of the lake evolution showed that the individual doses increase with a factor of hundred for Pu-239 during the life-time of the lake. For comparison doses have also been calculated for two differenct well scenarios in order to discuss the possibility of generic conversion factors from release to the biosphere and resulting individual doses. However, for all nuclides the obtained doses from exposure from a well situated in the discharge area to the lake were higher than for those obtained from the turnover of lake. For rough estimates the obtained doses can be used as standards when studying the impact on man from the turnover of long-lived radionuclides during the evolution of this type of ecosystem. (authors)

  12. Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality

    Science.gov (United States)

    Kravchenko, Julia; Akushevich, Igor; Abernethy, Amy P; Holman, Sheila; Ross, William G; Lyerly, H Kim

    2014-01-01

    Background The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina was associated with reduced rates of death from respiratory diseases in local populations. Materials and methods We analyzed the trends of emphysema, asthma, and pneumonia mortality and changes of the levels of ozone, sulfur dioxide (SO2), nitrogen dioxide (NO2), carbon monoxide (CO), and particulate matters (PM2.5 and PM10) using monthly data measurements from air-monitoring stations in North Carolina in 1993–2010. The log-linear model was used to evaluate associations between air-pollutant levels and age-adjusted death rates (per 100,000 of population) calculated for 5-year age-groups and for standard 2000 North Carolina population. The studied associations were adjusted by age group-specific smoking prevalence and seasonal fluctuations of disease-specific respiratory deaths. Results Decline in emphysema deaths was associated with decreasing levels of SO2 and CO in the air, decline in asthma deaths–with lower SO2, CO, and PM10 levels, and decline in pneumonia deaths–with lower levels of SO2. Sensitivity analyses were performed to study potential effects of the change from International Classification of Diseases (ICD)-9 to ICD-10 codes, the effects of air pollutants on mortality during summer and winter, the impact of approach when only the underlying causes of deaths were used, and when mortality and air-quality data were analyzed on the county level. In each case, the results of sensitivity analyses demonstrated stability. The importance of analysis of pneumonia as an underlying cause of death was also highlighted. Conclusion Significant associations were observed between decreasing death rates of emphysema, asthma, and pneumonia and decreases in levels of ambient air pollutants in North Carolina. PMID:25018627

  13. The dynamics of blood biochemical parameters in cosmonauts during long-term space flights

    Science.gov (United States)

    Markin, Andrei; Strogonova, Lubov; Balashov, Oleg; Polyakov, Valery; Tigner, Timoty

    Most of the previously obtained data on cosmonauts' metabolic state concerned certain stages of the postflight period. In this connection, all conclusions, as to metabolism peculiarities during the space flight, were to a large extent probabilistic. The purpose of this work was study of metabolism characteristics in cosmonauts directly during long-term space flights. In the capillary blood samples taken from a finger, by "Reflotron IV" biochemical analyzer, "Boehringer Mannheim" GmbH, Germany, adapted to weightlessness environments, the activity of GOT, GPT, CK, gamma-GT, total and pancreatic amylase, as well as concentration of hemoglobin, glucose, total bilirubin, uric acid, urea, creatinine, total, HDL- and LDL cholesterol, triglycerides had been determined. HDL/LDL-cholesterol ratio also was computed. The crewmembers of 6 main missions to the "Mir" orbital station, a total of 17 cosmonauts, were examined. Biochemical tests were carryed out 30-60 days before lounch, and in the flights different stages between the 25-th and the 423-rd days of flights. In cosmonauts during space flight had been found tendency to increase, in compare with basal level, GOT, GPT, total amylase activity, glucose and total cholesterol concentration, and tendency to decrease of CK activity, hemoglobin, HDL-cholesterol concentration, and HDL/LDL — cholesterol ratio. Some definite trends in variations of other determined biochemical parameters had not been found. The same trends of mentioned biochemical parameters alterations observed in majority of tested cosmonauts, allows to suppose existence of connection between noted metabolic alterations with influence of space flight conditions upon cosmonaut's body. Variations of other studied blood biochemical parameters depends on, probably, pure individual causes.

  14. Introducing litter quality to the ecosystem model LPJ-GUESS: Effects on short- and long-term soil carbon dynamics

    Science.gov (United States)

    Portner, Hanspeter; Wolf, Annett; Rühr, Nadine; Bugmann, Harald

    2010-05-01

    Many biogeochemical models have been applied to study the response of the carbon cycle to changes in climate, whereby the process of carbon uptake (photosynthesis) has usually gained more attention than the equally important process of carbon release by respiration. The decomposition of soil organic matter is driven by a combination of factors like soil temperature, soil moisture and litter quality. We have introduced dependence on litter substrate quality to heterotrophic soil respiration in the ecosystem model LPJ-GUESS [Smith et al.(2001)]. We were interested in differences in model projections before and after the inclusion of the dependency both in respect to short- and long-term soil carbon dynamics. The standard implementation of heterotrophic soil respiration in LPJ-GUESS is a simple carbon three-pool model whose decay rates are dependent on soil temperature and soil moisture. We have added dependence on litter quality by coupling LPJ-GUESS to the soil carbon model Yasso07 [Tuomi et al.(2008)]. The Yasso07 model is based on an extensive number of measurements of litter decomposition of forest soils. Apart from the dependence on soil temperature and soil moisture, the Yasso07 model uses carbon soil pools representing different substrate qualities: acid hydrolyzable, water soluble, ethanol soluble, lignin compounds and humus. Additionally Yasso07 differentiates between woody and non-woody litter. In contrary to the reference implementation of LPJ-GUESS, in the new model implementation, the litter now is divided according to its specific quality and added to the corresponding soil carbon pool. The litter quality thereby differs between litter source (leaves, roots, stems) and plant functional type (broadleaved, needleleaved, grass). The two contrasting model implementations were compared and validated at one specific CarboEuropeIP site (Lägern, Switzerland) and on a broader scale all over Switzerland. Our focus lay on the soil respiration for the years 2006

  15. Dynamic Regulation of Circulating microRNAs During Acute Exercise and Long-Term Exercise Training in Basketball Athletes

    Directory of Open Access Journals (Sweden)

    Yongqin Li

    2018-03-01

    Full Text Available Emerging evidence indicates the beneficial effects of physical exercise on human health, which depends on the intensity, training time, exercise type, environmental factors, and the personal health status. Conventional biomarkers provide limited insight into the exercise-induced adaptive processes. Circulating microRNAs (miRNAs, miRs are dynamically regulated in response to acute exhaustive exercise and sustained rowing, running and cycling exercises. However, circulating miRNAs in response to long-term basketball exercise remains unknown. Here, we enrolled 10 basketball athletes who will attend a basketball season for 3 months. Specifically, circulating miRNAs which were involved in angiogenesis, inflammation and enriched in muscle and/or cardiac tissues were analyzed at baseline, immediately following acute exhaustive exercise and after 3-month basketball matches in competitive male basketball athletes. Circulating miR-208b was decreased and miR-221 was increased after 3-month basketball exercise, while circulating miR-221, miR-21, miR-146a, and miR-210 were reduced at post-acute exercise. The change of miR-146a (baseline vs. post-acute exercise showed linear correlations with baseline levels of cardiac marker CKMB and the changes of inflammation marker Hs-CRP (baseline vs. post-acute exercise. Besides, linear correlation was observed between miR-208b changes (baseline vs. after long-term exercise and AT VO2 (baseline. The changes of miR-221 (baseline vs. after long-term exercise were significantly correlated with AT VO2, peak work load and CK (after 3-month basketball matches. Although further studies are needed, present findings set the stage for defining circulating miRNAs as biomarkers and suggesting their physiological roles in long-term exercise training induced cardiovascular adaptation.

  16. Dynamic Regulation of Circulating microRNAs During Acute Exercise and Long-Term Exercise Training in Basketball Athletes.

    Science.gov (United States)

    Li, Yongqin; Yao, Mengchao; Zhou, Qiulian; Cheng, Yan; Che, Lin; Xu, Jiahong; Xiao, Junjie; Shen, Zhongming; Bei, Yihua

    2018-01-01

    Emerging evidence indicates the beneficial effects of physical exercise on human health, which depends on the intensity, training time, exercise type, environmental factors, and the personal health status. Conventional biomarkers provide limited insight into the exercise-induced adaptive processes. Circulating microRNAs (miRNAs, miRs) are dynamically regulated in response to acute exhaustive exercise and sustained rowing, running and cycling exercises. However, circulating miRNAs in response to long-term basketball exercise remains unknown. Here, we enrolled 10 basketball athletes who will attend a basketball season for 3 months. Specifically, circulating miRNAs which were involved in angiogenesis, inflammation and enriched in muscle and/or cardiac tissues were analyzed at baseline, immediately following acute exhaustive exercise and after 3-month basketball matches in competitive male basketball athletes. Circulating miR-208b was decreased and miR-221 was increased after 3-month basketball exercise, while circulating miR-221, miR-21, miR-146a, and miR-210 were reduced at post-acute exercise. The change of miR-146a (baseline vs. post-acute exercise) showed linear correlations with baseline levels of cardiac marker CKMB and the changes of inflammation marker Hs-CRP (baseline vs. post-acute exercise). Besides, linear correlation was observed between miR-208b changes (baseline vs. after long-term exercise) and AT VO 2 (baseline). The changes of miR-221 (baseline vs. after long-term exercise) were significantly correlated with AT VO 2 , peak work load and CK (after 3-month basketball matches). Although further studies are needed, present findings set the stage for defining circulating miRNAs as biomarkers and suggesting their physiological roles in long-term exercise training induced cardiovascular adaptation.

  17. Dynamic Modeling and Very Short-term Prediction of Wind Power Output Using Box-Cox Transformation

    Science.gov (United States)

    Urata, Kengo; Inoue, Masaki; Murayama, Dai; Adachi, Shuichi

    2016-09-01

    We propose a statistical modeling method of wind power output for very short-term prediction. The modeling method with a nonlinear model has cascade structure composed of two parts. One is a linear dynamic part that is driven by a Gaussian white noise and described by an autoregressive model. The other is a nonlinear static part that is driven by the output of the linear part. This nonlinear part is designed for output distribution matching: we shape the distribution of the model output to match with that of the wind power output. The constructed model is utilized for one-step ahead prediction of the wind power output. Furthermore, we study the relation between the prediction accuracy and the prediction horizon.

  18. Dynamical behaviors of the shock compacton in the nonlinearly Schrödinger equation with a source term

    International Nuclear Information System (INIS)

    Yin, Jiuli; Zhao, Liuwei

    2014-01-01

    In this paper, the dynamics from the shock compacton to chaos in the nonlinearly Schrödinger equation with a source term is investigated in detail. The existence of unclosed homoclinic orbits which are not connected with the saddle point indicates that the system has a discontinuous fiber solution which is a shock compacton. We prove that the shock compacton is a weak solution. The Melnikov technique is used to detect the conditions for the occurrence from the shock compacton to chaos and further analysis of the conditions for chaos suppression. The results show that the system turns to chaos easily under external disturbances. The critical parameter values for chaos appearing are obtained analytically and numerically using the Lyapunov exponents and the bifurcation diagrams

  19. Long-term dynamics of death rates of emphysema, asthma, and pneumonia and improving air quality

    Directory of Open Access Journals (Sweden)

    Kravchenko J

    2014-06-01

    Full Text Available Julia Kravchenko,1 Igor Akushevich,2 Amy P Abernethy,3 Sheila Holman,4 William G Ross Jr,5 H Kim Lyerly1,6 1Department of Surgery, 2Center for Population Health and Aging, 3Duke Clinical Research Institute, Duke University Medical Center, Duke University, Durham, 4Division of Air Quality, North Carolina Department of Environment and Natural Resources, Raleigh, 5Nicholas School of the Environment, 6Department of Pathology, Duke University Medical Center, Duke University, Durham, NC, USA Background: The respiratory tract is a major target of exposure to air pollutants, and respiratory diseases are associated with both short- and long-term exposures. We hypothesized that improved air quality in North Carolina was associated with reduced rates of death from respiratory diseases in local populations. Materials and methods: We analyzed the trends of emphysema, asthma, and pneumonia mortality and changes of the levels of ozone, sulfur dioxide (SO2, nitrogen dioxide (NO2, carbon monoxide (CO, and particulate matters (PM2.5 and PM10 using monthly data measurements from air-monitoring stations in North Carolina in 1993–2010. The log-linear model was used to evaluate associations between air-pollutant levels and age-adjusted death rates (per 100,000 of population calculated for 5-year age-groups and for standard 2000 North Carolina population. The studied associations were adjusted by age group-specific smoking prevalence and seasonal fluctuations of disease-specific respiratory deaths. Results: Decline in emphysema deaths was associated with decreasing levels of SO2 and CO in the air, decline in asthma deaths–with lower SO2, CO, and PM10 levels, and decline in pneumonia deaths–with lower levels of SO2. Sensitivity analyses were performed to study potential effects of the change from International Classification of Diseases (ICD-9 to ICD-10 codes, the effects of air pollutants on mortality during summer and winter, the impact of approach when only

  20. Study of the intermediate-energy nucleon-nucleus reactions in terms of the quantum molecular dynamics

    International Nuclear Information System (INIS)

    Chiba, Satoshi; Niita, Koji; Maruyama, Toshiki; Fukahori, Tokio; Takada, Hiroshi; Iwamoto, Akira

    1995-01-01

    The double-differential (p,xp') and (p,xn) reaction cross sections of 58 Ni and 90 Zr in the energy range from 120 to 200 MeV have been studied in terms of the Quantum Molecular Dynamics. It was found that the present calculation could give a quantitative explanation of experimentally observed values of both channels simultaneously without adjusting any parameter, showing the usefulness of the QMD approach to study the pre-equilibrium process in this energy region. Comparisons were also made with prediction of other theories such as Antisymmetrized Molecular Dynamics (AMD) and semiclassical distorted wave theory. Effect of the anti-symmetrization, which is in AMD but not in QMD, was found surprisingly small, being the result of QMD even slightly better. At the same time, it was found that the present calculation does not give the quasi-free peak of the 1-step cross sections similar to the semiclassical model, due probably to different treatment of the refraction and acceleration effects caused by the mean field. (author)

  1. NUMERICAL SIMULATION OF YIELDING SUPPORTS IN THE SHAPE OF ANNULAR TUBES UNDER STATIC AND SHORT-TERM DYNAMIC LOADING

    Directory of Open Access Journals (Sweden)

    Oleg G. Kumpyak

    2017-12-01

    Full Text Available Occurrence of extreme man-made impacts on buildings and structures has become frequent lately as a consequence of condensed explosives or explosive combustion of gas- vapor or air-fuel mixtures. Such accidents involve large human and economic losses, and their prevention methods are not always effective and reasonable. The given research aims at studying the way of enhancing explosion safety of building structures by means of yielding supports. The paper presents results of numerical studies (finite element, 3D nonlinear of strength and deformability of yielding supports in the shape of annular tubes under static and short-term dynamic loading. The degree of influence of yielding supports was assessed taking into account three peculiar stages of deformation: elastic; elasto-plastic; elasto-plastic with hardening. The methodology for numerical studies performance was described. It was established that rigidity of yielding supports influences significantly their stress-strain state. The research determined that with increase of deformable elements rigidity dependency between load and deformation of yielding supports in elastic and plastic stages have linear character. Significant reduction of dynamic response and increase of deformation time of yielding supports was observed by increasing the plastic component. Therefore it allows assuming on possibility of their application as supporting units in reinforced concrete constructions

  2. Modelling and forecasting long-term dynamics of Western Baltic macrobenthic fauna in relation to climate signals and environmental change

    Science.gov (United States)

    Gröger, Joachim; Rumohr, Heye

    2006-05-01

    Long-term macrobenthos data from Kiel Bight in the Western Baltic collected between 1968 and 2000 have been correlated with the winter NAO index (North Atlantic Oscillation Index) and other environmental data such as temperature, salinity and oxygen content in the bottom water in order to detect systematic patterns related to so far unexplained abiotic signals in the dynamics of zoobenthic species assemblages. The benthos data come from a cluster of five stations (Süderfahrt/ Millionenviertel) in Kiel Bay. Our investigations concentrated on the macrobenthic dynamics with a focus on the number of species m - 2 (species richness). Using logarithms and the time series analysis approach of Box/Jenkins (ARIMA modelling, transfer function modelling) it was shown that species richness was strongly influenced by the winter NAO (adjusted for a linear time trend within the 1968-2000 period) and salinity (with a shift/lag of four years). Bootstrapping experiments (i.e. sampling from the error process) and analysis of prediction power (by means of the one- or more-years leaving-out method) showed that the parameter estimates behaved in a stable way, leading to a relatively robust model.

  3. Stochastic Dynamic AC Optimal Power Flow Based on a Multivariate Short-Term Wind Power Scenario Forecasting Model

    Directory of Open Access Journals (Sweden)

    Wenlei Bai

    2017-12-01

    Full Text Available The deterministic methods generally used to solve DC optimal power flow (OPF do not fully capture the uncertainty information in wind power, and thus their solutions could be suboptimal. However, the stochastic dynamic AC OPF problem can be used to find an optimal solution by fully capturing the uncertainty information of wind power. That uncertainty information of future wind power can be well represented by the short-term future wind power scenarios that are forecasted using the generalized dynamic factor model (GDFM—a novel multivariate statistical wind power forecasting model. Furthermore, the GDFM can accurately represent the spatial and temporal correlations among wind farms through the multivariate stochastic process. Fully capturing the uncertainty information in the spatially and temporally correlated GDFM scenarios can lead to a better AC OPF solution under a high penetration level of wind power. Since the GDFM is a factor analysis based model, the computational time can also be reduced. In order to further reduce the computational time, a modified artificial bee colony (ABC algorithm is used to solve the AC OPF problem based on the GDFM forecasting scenarios. Using the modified ABC algorithm based on the GDFM forecasting scenarios has resulted in better AC OPF’ solutions on an IEEE 118-bus system at every hour for 24 h.

  4. Examination of the rheological properties of stirred joghurt during the long-term storage by using dynamic oscillation method

    Directory of Open Access Journals (Sweden)

    Milica Vilušić

    2003-07-01

    Full Text Available In this work the rheological properties of stirred yoghurt during the longterm storage at 4 and 8°C were investigated. The optimal quantity of additives, in order to increase dry matter content (whole milk powder and whey protein-lactalbumin, was preliminary determined and the fermentation was performed. During 42 days, i.e., 1st, 7th, 14th, 21st, 28th, 35th and 42nd day of storage of stirred yoghurt, in refrigerator at 4 and 8°C, the changes of pH value, acidity and rheological properties by using of dynamic oscillation method were observed. Results of this work indicated that an addition of whole milk powder and whey protein have an influence on rheological properties of stirred yoghurt. The long-term storage of stirred yoghurt and the results of dynamic oscilations showed permanently higher G’storage (elasticity modulus, where elastic properties of viscoelastic products dominate, in comparison with the G” loss (viscosity modulus. Increased moduls of elasticy and viscosity, as function of time, permanently occurs at pH value 4.00 and lower, as an indication of alteration of long casein chains in the coagulum structure. Different temperatures of storage had no influence on changes of rheological properties of examinated types of stirred yoghur. The relation of above mentioned moduls of elasticy and viscosity kept the same increasing tendency.

  5. Long-term evaluation of orbital dynamics in the Sun-planet system considering axial-tilt

    Science.gov (United States)

    Bakhtiari, Majid; Daneshjou, Kamran

    2018-05-01

    In this paper, the axial-tilt (obliquity) effect of planets on the motion of planets’ orbiter in prolonged space missions has been investigated in the presence of the Sun gravity. The proposed model is based on non-simplified perturbed dynamic equations of planetary orbiter motion. From a new point of view, in this work, the dynamic equations regarding a disturbing body in elliptic inclined three-dimensional orbit are derived. The accuracy of this non-simplified method is validated with dual-averaged method employed on a generalized Earth-Moon system. It is shown that the neglected short-time oscillations in dual-averaged technique can accumulate and propel to remarkable errors in the prolonged evolution. After validation, the effects of the planet’s axial-tilt on eccentricity, inclination and right ascension of the ascending node of the orbiter are investigated. Moreover, a generalized model is provided to study the effects of third-body inclination and eccentricity on orbit characteristics. It is shown that the planet’s axial-tilt is the key to facilitating some significant changes in orbital elements in long-term mission and short-time oscillations must be considered in accurate prolonged evaluation.

  6. Impacts of Insufficient Observations on the Monitoring of Short- and Long-Term Suspended Solids Variations in Highly Dynamic Waters, and Implications for an Optimal Observation Strategy

    Directory of Open Access Journals (Sweden)

    Qu Zhou

    2018-02-01

    Full Text Available Coastal water regions represent some of the most fragile ecosystems, exposed to both climate change and human activities. While remote sensing provides unprecedented amounts of data for water quality monitoring on regional to global scales, the performance of satellite observations is frequently impeded by revisiting intervals and unfavorable conditions, such as cloud coverage and sun glint. Therefore, it is crucial to evaluate the impacts of varied sampling strategies (time and frequency and insufficient observations on the monitoring of short-term and long-term tendencies of water quality parameters, such as suspended solids (SS, in highly dynamic coastal waters. Taking advantage of the first high-frequency in situ SS dataset (at 30 min sampling intervals from 2007 to 2008, collected in Deep Bay, China, this paper presents a quantitative analysis of the influences of sampling strategies on the monitoring of SS, in terms of sampling frequency and time of day. Dramatic variations of SS were observed, with standard deviation coefficients of 48.9% and 54.1%, at two fixed stations; in addition, significant uncertainties were revealed, with the average absolute percent difference of approximately 13%, related to sampling frequency and time, using nonlinear optimization and random simulation methods. For a sampling frequency of less than two observations per day, the relative error of SS was higher than 50%, and stabilized at approximately 10%, when at least four or five samplings were conducted per day. The optimal recommended sampling times for SS were at around 9:00, 12:00, 14:00, and 16:00 in Deep Bay. The “pseudo” MODIS SS dataset was obtained from high-frequency in situ SS measurements at 10:30 and 14:00, masked by the temporal gap distribution of MODIS coverage to avoid uncertainties propagated from atmospheric correction and SS models. Noteworthy uncertainties of daily observations from the Terra/Aqua MODIS were found, with mean relative

  7. Climate projections and extremes in dynamically downscaled CMIP5 model outputs over the Bengal delta: a quartile based bias-correction approach with new gridded data

    Science.gov (United States)

    Hasan, M. Alfi; Islam, A. K. M. Saiful; Akanda, Ali Shafqat

    2017-11-01

    In the era of global warning, the insight of future climate and their changing extremes is critical for climate-vulnerable regions of the world. In this study, we have conducted a robust assessment of Regional Climate Model (RCM) results in a monsoon-dominated region within the new Coupled Model Intercomparison Project Phase 5 (CMIP5) and the latest Representative Concentration Pathways (RCP) scenarios. We have applied an advanced bias correction approach to five RCM simulations in order to project future climate and associated extremes over Bangladesh, a critically climate-vulnerable country with a complex monsoon system. We have also generated a new gridded product that performed better in capturing observed climatic extremes than existing products. The bias-correction approach provided a notable improvement in capturing the precipitation extremes as well as mean climate. The majority of projected multi-model RCMs indicate an increase of rainfall, where one model shows contrary results during the 2080s (2071-2100) era. The multi-model mean shows that nighttime temperatures will increase much faster than daytime temperatures and the average annual temperatures are projected to be as hot as present-day summer temperatures. The expected increase of precipitation and temperature over the hilly areas are higher compared to other parts of the country. Overall, the projected extremities of future rainfall are more variable than temperature. According to the majority of the models, the number of the heavy rainy days will increase in future years. The severity of summer-day temperatures will be alarming, especially over hilly regions, where winters are relatively warm. The projected rise of both precipitation and temperature extremes over the intense rainfall-prone northeastern region of the country creates a possibility of devastating flash floods with harmful impacts on agriculture. Moreover, the effect of bias-correction, as presented in probable changes of both bias-corrected

  8. Dynamics and Structure of Dispute in Open Group of Facebook Social Networking Service in Terms of Teenagers’ Homosexual Relations Education

    Directory of Open Access Journals (Sweden)

    Sergei V. Kharitonov

    2014-05-01

    Full Text Available The article considers the results of discussions in the group of Facebook social networking service, dealing with the problem of teenagers’ homosexual relations education. The goal of the research is to study the dynamics of the dispute in Facebook social networking service on the example of the closed group “Teenagers’ Sexual Orientation”. As a whole, 72 people participated in the discussion, involving both representatives, sharing the views of the LGBT community, concerning homosexual relations and teenagers’ heterosexual parents. As a result of the dispute, conducted within Facebook website 230 comments were left. Resulting from the content analysis of the message texts, the estimation of a number of parameters was made. The estimation showed that the parties of the virtual discussion are in deficit of decisions in terms of virtual disputes conduct. The declared wish to argue out doesn’t lead to the real activity, relevant to evidence-based disputes. Thus, we can consider that the participants of the virtual discussion are in deficit of the decisions in terms of virtual disputes conduct.

  9. Sampling strategies and stopping criteria for stochastic dual dynamic programming: a case study in long-term hydrothermal scheduling

    Energy Technology Data Exchange (ETDEWEB)

    Homem-de-Mello, Tito [University of Illinois at Chicago, Department of Mechanical and Industrial Engineering, Chicago, IL (United States); Matos, Vitor L. de; Finardi, Erlon C. [Universidade Federal de Santa Catarina, LabPlan - Laboratorio de Planejamento de Sistemas de Energia Eletrica, Florianopolis (Brazil)

    2011-03-15

    The long-term hydrothermal scheduling is one of the most important problems to be solved in the power systems area. This problem aims to obtain an optimal policy, under water (energy) resources uncertainty, for hydro and thermal plants over a multi-annual planning horizon. It is natural to model the problem as a multi-stage stochastic program, a class of models for which algorithms have been developed. The original stochastic process is represented by a finite scenario tree and, because of the large number of stages, a sampling-based method such as the Stochastic Dual Dynamic Programming (SDDP) algorithm is required. The purpose of this paper is two-fold. Firstly, we study the application of two alternative sampling strategies to the standard Monte Carlo - namely, Latin hypercube sampling and randomized quasi-Monte Carlo - for the generation of scenario trees, as well as for the sampling of scenarios that is part of the SDDP algorithm. Secondly, we discuss the formulation of stopping criteria for the optimization algorithm in terms of statistical hypothesis tests, which allows us to propose an alternative criterion that is more robust than that originally proposed for the SDDP. We test these ideas on a problem associated with the whole Brazilian power system, with a three-year planning horizon. (orig.)

  10. Impact of human milk pasteurization on the kinetics of peptide release during in vitro dynamic term newborn digestion.

    Science.gov (United States)

    Deglaire, Amélie; De Oliveira, Samira C; Jardin, Julien; Briard-Bion, Valérie; Emily, Mathieu; Ménard, Olivia; Bourlieu, Claire; Dupont, Didier

    2016-07-01

    Holder pasteurization (62.5°C, 30 min) ensures sanitary quality of donor's human milk but also denatures beneficial proteins. Understanding whether this further impacts the kinetics of peptide release during gastrointestinal digestion of human milk was the aim of the present paper. Mature raw (RHM) or pasteurized (PHM) human milk were digested (RHM, n = 2; PHM, n = 3) by an in vitro dynamic system (term stage). Label-free quantitative peptidomics was performed on milk and digesta (ten time points). Ascending hierarchical clustering was conducted on "Pasteurization × Digestion time" interaction coefficients. Preproteolysis occurred in human milk (159 unique peptides; RHM: 91, PHM: 151), mostly on β-casein (88% of the endogenous peptides). The predicted cleavage number increased with pasteurization, potentially through plasmin activation (plasmin cleavages: RHM, 53; PHM, 76). During digestion, eight clusters resumed 1054 peptides from RHM and PHM, originating for 49% of them from β-casein. For seven clusters (57% of peptides), the kinetics of peptide release differed between RHM and PHM. The parent protein was significantly linked to the clustering (p-value = 1.4 E-09), with β-casein and lactoferrin associated to clusters in an opposite manner. Pasteurization impacted selectively gastric and intestinal kinetics of peptide release in term newborns, which may have further nutritional consequences. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  11. Local Seismicity Recorded by ChilePEPPER: Implications for Dynamic Accretionary Prism Response and Long-term Prism Evolution

    Science.gov (United States)

    de Moor, A.; Trehu, A. M.; Tryon, M. D.

    2015-12-01

    To investigate the dynamic response of the outer accretionary wedge updip from the patch of greatest slip during the Mw8.8 2010 Maule earthquake, 10 Ocean Bottom Seismometers (OBS) were deployed from May 2012 to March 2013 in a small array with an inter-instrument spacing of ~12 km . Nine instruments were recovered, with 4 recording data on 3 intermediate-band 3-component seismometers and a differential pressure gauge and 5 recording data from absolute pressure gauges. [note: All instruments were also equipped with a fluid flow meter sensitive to flow rates as low as 0.0001 cm/yr in or out of the sediments. However, no flow signal was detected.] Here we present hypocenters for 569 local events that have S-P times less than 17 seconds (i.e. within ~125 km of the array) using hand-picked arrival times and a 1D velocity model derived from a 2D seismic refraction profile through the region (Moscoso et al 2011, EPSL). We analyze the distribution of seismicity in the context of published slip models, ChilePEPPER high-resolution seismic reflection data, critical taper analysis done by Cubas et al 2013 (EPSL), and offshore gravity data. The data show distinct segmentation within the outer prism. The northern section of the study area is characterized by a lack of seismicity, accretion of nearly all incoming sediment and a prism at critical taper. In contrast, abundant seismicity, significant sediment underthrusting at the deformation front and a prism below critical taper angle characterize the southern part of the study area. Both coseismic slip and post-rupture local seismicity can be related to density anomalies within the upper plate as revealed by free air gravity data corrected for the effects of bathymetry and the subducting plate. [ChilePEPPER - Project Evaluating Prism Post-Earthquake Response

  12. Dynamic Strength and Accumulated Plastic Strain Development Laws and Models of the Remolded Red Clay under Long-Term Cyclic Loads: Laboratory Test Results

    Directory of Open Access Journals (Sweden)

    Li Jian

    2015-09-01

    Full Text Available The dynamic strength and accumulated plastic strain are two important parameters for evaluating the dynamic response of soil. As a special clay, the remolded red clay is often used as the high speed railway subgrade filling, but studies on its dynamic characteristics are few. For a thorough analysis of the suitability of the remolded red clay as the subgrade filling, a series of long-term cyclic load triaxial test under different load histories are carried out. Considering the influence of compactness, confining pressure, consolidation ratio, vibration frequency and dynamic load to the remolded red clay dynamic property, the tests obtain the development curves of the dynamic strength and accumulated plastic strain under different test conditions. Then, through curve fitting method, two different hyperbolic models respectively for the dynamic strength and accumulated plastic strain are built, which can match the test datum well. By applying the dynamic strength model, the critical dynamic strength of the remolded red clay are gained. Meanwhile, for providing basic datum and reference for relevant projects, all key parameters for the dynamic strength and accumulated plastic strain of the remolded red clay are given in the paper.

  13. Evaluation of the global orbit correction algorithm for the APS real-time orbit feedback system

    International Nuclear Information System (INIS)

    Carwardine, J.; Evans, K. Jr.

    1997-01-01

    The APS real-time orbit feedback system uses 38 correctors per plane and has available up to 320 rf beam position monitors. Orbit correction is implemented using multiple digital signal processors. Singular value decomposition is used to generate a correction matrix from a linear response matrix model of the storage ring lattice. This paper evaluates the performance of the APS system in terms of its ability to correct localized and distributed sources of orbit motion. The impact of regulator gain and bandwidth, choice of beam position monitors, and corrector dynamics are discussed. The weighted least-squares algorithm is reviewed in the context of local feedback

  14. System-size corrections for self-diffusion coefficients calculated from molecular dynamics simulations: The case of CO{sub 2}, n-alkanes, and poly(ethylene glycol) dimethyl ethers

    Energy Technology Data Exchange (ETDEWEB)

    Moultos, Othonas A.; Economou, Ioannis G. [Chemical Engineering Program, Texas A& M University at Qatar, P.O. Box 23847, Doha (Qatar); Zhang, Yong; Maginn, Edward J., E-mail: ed@nd.edu [Department of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556 (United States); Tsimpanogiannis, Ioannis N. [Chemical Engineering Program, Texas A& M University at Qatar, P.O. Box 23847, Doha (Qatar); Environmental Research Laboratory, National Center for Scientific Research “Demokritos,” 15310 Aghia Paraskevi Attikis (Greece)

    2016-08-21

    Molecular dynamics simulations were carried out to study the self-diffusion coefficients of CO{sub 2}, methane, propane, n-hexane, n-hexadecane, and various poly(ethylene glycol) dimethyl ethers (glymes in short, CH{sub 3}O–(CH{sub 2}CH{sub 2}O){sub n}–CH{sub 3} with n = 1, 2, 3, and 4, labeled as G1, G2, G3, and G4, respectively) at different conditions. Various system sizes were examined. The widely used Yeh and Hummer [J. Phys. Chem. B 108, 15873 (2004)] correction for the prediction of diffusion coefficient at the thermodynamic limit was applied and shown to be accurate in all cases compared to extrapolated values at infinite system size. The magnitude of correction, in all cases examined, is significant, with the smallest systems examined giving for some cases a self-diffusion coefficient approximately 15% lower than the infinite system-size extrapolated value. The results suggest that finite size corrections to computed self-diffusivities must be used in order to obtain accurate results.

  15. Long-term simulations of water and isoproturon dynamics in a heterogeneous soil receiving different urban waste composts

    Science.gov (United States)

    Filipović, Vilim; Coquet, Yves; Pot, Valérie; Romić, Davor; Benoit, Pierre; Houot, Sabine

    2016-04-01

    Implementing various compost amendments and tillage practices has a large influence on soil structure and can create heterogeneities at the plot/field scale. While tillage affects soil physical properties, compost application influences also chemical properties like pesticide sorption and degradation. A long-term field experiment called "QualiAgro" (https://www6.inra.fr/qualiagro_eng/), conducted since 1998 aims at characterizing the agronomic value of urban waste composts and their environmental impacts. A modeling study was carried out using HYDRUS-2D for the 2004-2010 period to confront the effects of two different compost types combined with the presence of heterogeneities due to tillage in terms of water and isoproturon dynamics in soil. A municipal solid waste compost (MSW) and a co-compost of sewage sludge and green wastes (SGW) have been applied to experimental plots and compared to a control plot without any compost addition (CONT). Two wick lysimeters, 5 TDR probes, and 7 tensiometers were installed per plot to monitor water and isoproturon dynamics. In the ploughed layer, four zones with differing soil structure were identified: compacted clods (Δ), non-compacted soil (Γ), interfurrows (IF), and the plough pan (PP). These different soil structural zones were implemented into HYDRUS-2D according to field observation and using measured soil hydraulic properties. Lysimeter data showed (2004 -2010 period) that the CONT plot had the largest cumulative water outflow (1388 mm) compared to the MSW plot (962 mm) and SGW plot (979 mm). HYDRUS-2D was able to describe cumulative water outflow after calibration of soil hydraulic properties, for the whole 2004-2010 period with a model efficiency value of 0.99 for all three plots. Isoproturon leaching showed had the largest cumulative value in the CONT plot (21.31 μg) while similar cumulated isoproturon leachings were measured in the SGW (0.663 μg) and MSW (0.245 μg) plots. The model was able to simulate

  16. Reoperation after radical correction tetralogy of Fallot: results and prospects

    Directory of Open Access Journals (Sweden)

    M.F. Zinkovskyi

    2017-06-01

    Full Text Available The aim – to present experience, results and prospects of repeated interventions in the remote period after radical correction of tetralogy of Fallot. Materials and methods. Results of the repeated 65 surgeries in 62 patients after radical correction of tetralogy of Fallot with long-term follow-up for the period from 1981 to 2014 are presented. The interval between the radical tetralogy of Fallot correction and re-operation ranged from 1 month to 30 years (average – 8.54 ± 6.3 years. Results. Depending on the predominance of one or other complications and its causes we observed: 1 residual defects – 25 (40.4 % cases; right ventricular dysfunction – 23 (37.0 % cases; valve pathology – 5 (8.0 % cases; other rare complications – 9 (14.6 % cases. In total, 100 complications were identified and eliminated in 62 patients. The most frequent complications that required second surgical correction were: recanalization of ventricular septal defect (36.0 %, right ventricular aneurysm (19.0 %, tricuspid valve insufficiency (13.0 %, the residual obstruction of the outflow tract of the right ventricle (9.0 %, right ventricular dysfunction caused by pulmonary valve insufficiency (6.0 % and pulmonary trunk aneurysm (5.0 %. Conclusion. Hospital mortality after surgical correction of long-term complications was 8.0 %. All discharged patients with echocardiographic evaluation revealed a positive dynamics of volume and functional parameters of the right and left ventricles

  17. Short-term dissolved organic carbon dynamics reflect water management and precipitation patterns in a subtropical estuary

    Directory of Open Access Journals (Sweden)

    Peter Regier

    2016-12-01

    a better understanding of short-term DOC dynamics and associated hydrological drivers and indicates the importance of high-frequency measurements to accurately constraining coastal carbon processes and budgets, particularly in coastal systems increasingly altered by hydrologic restoration and climate change.

  18. Cosmological dynamics of spatially flat Einstein-Gauss-Bonnet models in various dimensions: high-dimensional Λ-term case

    Energy Technology Data Exchange (ETDEWEB)

    Pavluchenko, Sergey A. [Universidade Federal do Maranhao (UFMA), Programa de Pos-Graduacao em Fisica, Sao Luis, Maranhao (Brazil)

    2017-08-15

    In this paper we perform a systematic study of spatially flat [(3+D)+1]-dimensional Einstein-Gauss-Bonnet cosmological models with Λ-term. We consider models that topologically are the product of two flat isotropic subspaces with different scale factors. One of these subspaces is three-dimensional and represents our space and the other is D-dimensional and represents extra dimensions. We consider no ansatz of the scale factors, which makes our results quite general. With both Einstein-Hilbert and Gauss-Bonnet contributions in play, D = 3 and the general D ≥ 4 cases have slightly different dynamics due to the different structure of the equations of motion. We analytically study the equations of motion in both cases and describe all possible regimes with special interest on the realistic regimes. Our analysis suggests that the only realistic regime is the transition from high-energy (Gauss-Bonnet) Kasner regime, which is the standard cosmological singularity in that case, to the anisotropic exponential regime with expanding three and contracting extra dimensions. Availability of this regime allows us to put a constraint on the value of Gauss-Bonnet coupling α and the Λ-term - this regime appears in two regions on the (α, Λ) plane: α < 0, Λ > 0, αΛ ≤ -3/2 and α > 0, αΛ ≤ (3D{sup 2} - 7D + 6)/(4D(D-1)), including the entire Λ < 0 region. The obtained bounds are confronted with the restrictions on α and Λ from other considerations, like causality, entropy-to-viscosity ratio in AdS/CFT and others. Joint analysis constrains (α, Λ) even further: α > 0, D ≥ 2 with (3D{sup 2} - 7D + 6)/(4D(D-1)) ≥ αΛ ≥ -(D+2)(D+3)(D{sup 2} + 5D + 12)/(8(D{sup 2} + 3D + 6){sup 2}). (orig.)

  19. Role of short-term dispersal on the dynamics of Zika virus in an extreme idealized environment

    Directory of Open Access Journals (Sweden)

    Victor M. Moreno

    2017-02-01

    Full Text Available In November 2015, El Salvador reported their first case of Zika virus (ZIKV infection, an event followed by an explosive outbreak that generated over 6000 suspected cases in a period of two months. National agencies began implementing control measures that included vector control and recommending an increased use of repellents. Further, in response to the alarming and growing number of microcephaly cases in Brazil, the importance of avoiding pregnancies for two years was stressed. In this paper, we explore the role of mobility within communities characterized by extreme poverty, crime and violence. Specifically, the role of short term mobility between two idealized interconnected highly distinct communities is explored in the context of ZIKV outbreaks. We make use of a Lagrangian modeling approach within a two-patch setting in order to highlight the possible effects that short-term mobility, within highly distinct environments, may have on the dynamics of ZIKV outbreak when the overall goal is to reduce the number of cases not just in the most affluent areas but everywhere. Outcomes depend on existing mobility patterns, levels of disease risk, and the ability of federal or state public health services to invest in resource limited areas, particularly in those where violence is systemic. The results of simulations in highly polarized and simplified scenarios are used to assess the role of mobility. It quickly became evident that matching observed patterns of ZIKV outbreaks could not be captured without incorporating increasing levels of heterogeneity. The number of distinct patches and variations on patch connectivity structure required to match ZIKV patterns could not be met within the highly aggregated model that is used in the simulations. Keywords: Vector-borne diseases, Zika virus, Residence times, Multi-patch model

  20. Long-term dynamics of investment decisions in electricity markets with variable renewables development and adequacy objectives

    International Nuclear Information System (INIS)

    Petitet, Marie

    2016-01-01

    In liberalised electricity systems, power markets are expected to ensure the long-term coordination of investments in order to guarantee security of supply, sustainability and competitiveness. In the reference energy-only market, it relies on the ability of power markets - where the hourly price is aligned with the marginal cost of the system - to provide an adequate price-signal for investors. However, in practice, questions have been raised about its ability to trigger investments in Low-Carbon Technologies (LCT) including in particular Renewable Energy Sources of Electricity (RES-E), and its ability to ensure capacity adequacy. After a characterisation of these market failures, this dissertation tackles the two research topics within a methodological framework based on a System Dynamics model developed to simulate private investment decisions in power markets. First, the results show that substituting out-of-market support mechanisms for RES-E by market-based investments helped by the sole implementation of a carbon price appears as a feasible solution to trigger RES-E development providing that there is a political commitment on a high carbon price. Second, it also appears that the energy-only market with price cap is ineffective to ensure capacity adequacy in a context of mature markets with conventional thermal power plants under transition paths which involve a stable electricity demand thank to energy efficiency efforts and the exogenous development of RES-E thanks to support mechanisms in the absence of a high and fixed carbon price. Adding a capacity market or removing the price cap both bring benefits in terms of Loss Of Load Expectation (LOLE) and social welfare. Moreover, considering two various energy transition scenarios and different assumptions about the risk aversion of private investors, the capacity market is identified as the best option for regulators among the considered market designs. (author) [fr

  1. Quantum corrections to nonlinear ion acoustic wave with Landau damping

    Energy Technology Data Exchange (ETDEWEB)

    Mukherjee, Abhik; Janaki, M. S. [Saha Institute of Nuclear Physics, Calcutta (India); Bose, Anirban [Serampore College, West Bengal (India)

    2014-07-15

    Quantum corrections to nonlinear ion acoustic wave with Landau damping have been computed using Wigner equation approach. The dynamical equation governing the time development of nonlinear ion acoustic wave with semiclassical quantum corrections is shown to have the form of higher KdV equation which has higher order nonlinear terms coming from quantum corrections, with the usual classical and quantum corrected Landau damping integral terms. The conservation of total number of ions is shown from the evolution equation. The decay rate of KdV solitary wave amplitude due to the presence of Landau damping terms has been calculated assuming the Landau damping parameter α{sub 1}=√(m{sub e}/m{sub i}) to be of the same order of the quantum parameter Q=ℏ{sup 2}/(24m{sup 2}c{sub s}{sup 2}L{sup 2}). The amplitude is shown to decay very slowly with time as determined by the quantum factor Q.

  2. Revisiting short-term price and volatility dynamics in day-ahead electricity markets with rising wind power

    International Nuclear Information System (INIS)

    Li, Yuanjing

    2015-01-01

    This paper revisits the short-term price and volatility dynamics in day-ahead electricity markets in consideration of an increasing share of wind power, using an example of the Nord Pool day-ahead market and the Danish wind generation. To do so, a GARCH process is applied, and market coupling and the counterbalance effect of hydropower in the Scandinavian countries are additionally accounted for. As results, we found that wind generation weakly dampens spot prices with an elasticity of 0.008 and also reduces price volatility with an elasticity of 0.02 in the Nordic day-ahead market. The results shed lights on the importance of market coupling and interactions between wind power and hydropower in the Nordic system through cross-border exchanges, which play an essential role in price stabilization. Additionally, an EGARCH specification confirms an asymmetric influence of the price innovations, whereby negative shocks produce larger volatility in the Nordic spot market. While considering heavy tails in error distributions can improve model fits significantly, the EGARCH model outperforms the GARCH model on forecast evaluations. (author)

  3. Long-term monitoring of streambed sedimentation and scour in a dynamic stream based on streambed temperature time series.

    Science.gov (United States)

    Sebok, Eva; Engesgaard, Peter; Duque, Carlos

    2017-08-24

    This study presented the monitoring and quantification of streambed sedimentation and scour in a stream with dynamically changing streambed based on measured phase and amplitude of the diurnal signal of sediment temperature time series. With the applied method, changes in streambed elevation were estimated on a sub-daily scale with 2-h intervals without continuous maintenance of the measurement system, thus making both high temporal resolution and long-term monitoring of streambed elevations possible. Estimates of streambed elevation showed that during base flow conditions streambed elevation fluctuates by 2-3 cm. Following high stream stages, scouring of 2-5 cm can be observed even at areas with low stream flow and weak currents. Our results demonstrate that weather variability can induce significant changes in the stream water and consequently sediment temperatures influencing the diurnal temperature signal in such an extent that the sediment thickness between paired temperature sensors were overestimated by up to 8 cm. These observations have significant consequences on the design of vertical sensor spacing in high-flux environments and in climates with reduced diurnal variations in air temperature.

  4. Identifying ecological "sweet spots" underlying cyanobacteria functional group dynamics from long-term observations using a statistical machine learning approach

    Science.gov (United States)

    Nelson, N.; Munoz-Carpena, R.; Phlips, E. J.

    2017-12-01

    Diversity in the eco-physiological adaptations of cyanobacteria genera creates challenges for water managers who are tasked with developing appropriate actions for controlling not only the intensity and frequency of cyanobacteria blooms, but also reducing the potential for blooms of harmful taxa (e.g., toxin producers, N2 fixers). Compounding these challenges, the efficacy of nutrient management strategies (phosphorus-only versus nitrogen-and-phosphorus) for cyanobacteria bloom abatement is the subject of an ongoing debate, which increases uncertainty associated with bloom mitigation decision-making. In this work, we analyze a unique long-term (17-year) dataset composed of monthly observations of cyanobacteria genera abundances, zooplankton abundances, water quality, and flow from Lake George, a bloom-impacted flow-through lake of the St. Johns River (FL, USA). Using the Random Forests machine learning algorithm, an assumption-free ensemble modeling approach, the dataset was evaluated to quantify and characterize relationships between environmental conditions and seven cyanobacteria groupings: five genera (Anabaena, Cylindrospermopsis, Lyngbya, Microcystis, and Oscillatoria) and two functional groups (N2 fixers and non-fixers). Results highlight the selectivity of nitrogen in describing genera and functional group dynamics, and potential for physical effects to limit the efficacy of nutrient management as a mechanism for cyanobacteria bloom mitigation.

  5. Mainstream upflow nitritation-anammox system with hybrid anaerobic pretreatment: Long-term performance and microbial community dynamics.

    Science.gov (United States)

    Li, Xiaojin; Sun, Shan; Yuan, Heyang; Badgley, Brian D; He, Zhen

    2017-11-15

    Mainstream nitritation-anammox is of strong interest to energy- and resource-efficient domestic wastewater treatment. However, there lack in-depth studies of pretreatment, tests of actual wastewater, and examination of long-term performance. Herein, an upflow nitritation-anammox granular reactor has been investigated to treat primary effluent with a hybrid anaerobic reactor (HAR) as pretreatment for more than 300 days. This system achieved 92% of COD removal, 75% of which was accomplished by the HAR, and had an average final effluent COD concentration of 22 mg L -1 . More than 90% of ammonium was removed in the nitritation-anammox reactor, achieving a nitrogen removal rate of 81.0 g N m -3  d -1 in the last stage. The accumulation of sulfate-reducing bacteria in the HAR evidenced the effect of sulfate on COD removal and subsequent nitrogen removal. Anammox bacteria (predominantly Ca. Jettenia asiatica) accounted for up to 40.2% of total granular communities, but their abundance decreased over time in the suspended communities. The dynamics of major metabolisms and functional genes involved in nitrogen conversion were predicted by PICRUSt based on the taxonomic data, providing more insights into the functions of the microbial communities. These results have demonstrated the effectiveness and importance of anaerobic pretreatment to successful mainstream nitritation-anammox. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Brane cosmology with curvature corrections

    International Nuclear Information System (INIS)

    Kofinas, Georgios; Maartens, Roy; Papantonopoulos, Eleftherios

    2003-01-01

    We study the cosmology of the Randall-Sundrum brane-world where the Einstein-Hilbert action is modified by curvature correction terms: a four-dimensional scalar curvature from induced gravity on the brane, and a five-dimensional Gauss-Bonnet curvature term. The combined effect of these curvature corrections to the action removes the infinite-density big bang singularity, although the curvature can still diverge for some parameter values. A radiation brane undergoes accelerated expansion near the minimal scale factor, for a range of parameters. This acceleration is driven by the geometric effects, without an inflation field or negative pressures. At late times, conventional cosmology is recovered. (author)

  7. Automatic Correction of Betatron Coupling in the LHC Using Injection Oscillations

    CERN Document Server

    Persson, T; Jacquet, D; Kain, V; Levinsen, Y; McAteer, M-J; Maclean, E; Skowronski, P; Tomas, R; Vanbavinckhove, G; Miyamoto, R

    2013-01-01

    The control of the betatron coupling at injection and during the energy ramp is critical for the safe operation of the tune feedback and for the dynamic aperture. In the LHC every fill is preceded by the injection of a pilot bunch with low intensity. Using the injection oscillations from the pilot bunch we are able to measure the coupling at each individual BPM. The measurement is used to calculate a global coupling correction. The correction is based on the use of two orthogonal knobs which correct the real and imaginary part of the difference resonance term f1001, respectively. This method to correct the betatron coupling has been proven successful during the normal operation of the LHC. This paper presents the method used to calculate the corrections and its performance.

  8. Dynamics

    CERN Document Server

    Goodman, Lawrence E

    2001-01-01

    Beginning text presents complete theoretical treatment of mechanical model systems and deals with technological applications. Topics include introduction to calculus of vectors, particle motion, dynamics of particle systems and plane rigid bodies, technical applications in plane motions, theory of mechanical vibrations, and more. Exercises and answers appear in each chapter.

  9. Corrective Jaw Surgery

    Medline Plus

    Full Text Available ... and Craniofacial Surgery Cleft Lip/Palate and Craniofacial Surgery A cleft lip may require one or more ... find out more. Corrective Jaw Surgery Corrective Jaw Surgery Orthognathic surgery is performed to correct the misalignment ...

  10. The Achievement of Therapeutic Objectives Scale: Interrater Reliability and Sensitivity to Change in Short-Term Dynamic Psychotherapy and Cognitive Therapy

    Science.gov (United States)

    Valen, Jakob; Ryum, Truls; Svartberg, Martin; Stiles, Tore C.; McCullough, Leigh

    2011-01-01

    This study examined interrater reliability and sensitivity to change of the Achievement of Therapeutic Objectives Scale (ATOS; McCullough, Larsen, et al., 2003) in short-term dynamic psychotherapy (STDP) and cognitive therapy (CT). The ATOS is a process scale originally developed to assess patients' achievements of treatment objectives in STDP,…

  11. Bäcklund transformation and soliton solutions in terms of the Wronskian for the Kadomtsev-Petviashvili-based system in fluid dynamics

    Science.gov (United States)

    Du, Zhong; Tian, Bo; Xie, Xi-Yang; Chai, Jun; Wu, Xiao-Yu

    2018-04-01

    In this paper, investigation is made on a Kadomtsev-Petviashvili-based system, which can be seen in fluid dynamics, biology and plasma physics. Based on the Hirota method, bilinear form and Bäcklund transformation (BT) are derived. N-soliton solutions in terms of the Wronskian are constructed, and it can be verified that the N-soliton solutions in terms of the Wronskian satisfy the bilinear form and Bäcklund transformation. Through the N-soliton solutions in terms of the Wronskian, we graphically obtain the kink-dark-like solitons and parallel solitons, which keep their shapes and velocities unchanged during the propagation.

  12. Medium-term effects of Dynesys dynamic stabilization versus posterior lumbar interbody fusion for treatment of multisegmental lumbar degenerative disease.

    Science.gov (United States)

    Wu, Haiting; Pang, Qingjiang; Jiang, Guoqiang

    2017-10-01

    Objective To compare the medium-term clinical and radiographic outcomes of Dynesys dynamic stabilization and posterior lumbar interbody fusion (PLIF) for treatment of multisegmental lumbar degenerative disease. Methods Fifty-seven patients with multisegmental lumbar degenerative disease underwent Dynesys stabilization (n = 26) or PLIF (n = 31) from December 2008 to February 2010. The mean follow-up period was 50.3 (range, 46-65) months. Clinical outcomes were evaluated using a visual analogue scale (VAS) and the Oswestry disability index (ODI). Radiographic evaluations included disc height and range of motion (ROM) of the operative segments and proximal adjacent segment on lumbar flexion-extension X-rays. The intervertebral disc signal change was defined by magnetic resonance imaging, and disc degeneration was classified by the Pfirrmann grade. Results The clinical outcomes including the VAS score and ODI were significantly improved in both groups at 3 months and the final follow-up, but the difference between the two was not significant. At the final follow-up, the disc height of stabilized segments in both groups was significantly increased; the increase was more notable in the Dynesys than PLIF group. The ROM of stabilized segments at the final follow-up decreased from 6.20° to 2.76° and 6.56° to 0.00° in the Dynesys and PLIF groups, respectively. There was no distinct change in the height of the proximal adjacent segment in the two groups. The ROM of the proximal adjacent segment in both groups increased significantly at the final follow-up; the change was significantly greater in the PLIF than Dynesys group. Only one case of adjacent segment degeneration occurred in the PLIF group, and this patient underwent a second operation. Conclusions Both Dynesys stabilization and PLIF can improve the clinical and radiographic outcomes of multisegmental lumbar degenerative disease. Compared with PLIF, Dynesys stabilization can maintain the mobility of the

  13. Generators of dynamical symmetries and the correct gauge transformation in the Landau level problem: use of pseudomomentum and pseudo-angular momentum

    Science.gov (United States)

    Konstantinou, Georgios; Moulopoulos, Konstantinos

    2016-11-01

    Due to the importance of gauge symmetry in all fields of physics, and motivated by an article written almost three decades ago that warns against a naive handling of gauge transformations in the Landau level problem (a quantum electron moving in a spatially uniform magnetic field), we point out a proper use of the generators of dynamical symmetries combined with gauge transformation methods to easily obtain exact analytical solutions for all Landau level-wavefunctions in arbitrary gauge. Our method is different from the old argument and provides solutions in an easier manner and in a broader set of geometries and gauges; in so doing, it eliminates the need for extra procedures (i.e. a change of basis) pointed out as a necessary step in the old literature, and gives back the standard simple result, provided that an appropriate use is made of the dynamical symmetries of the system and their generators. In this way the present work will at least be useful for university-level education, i.e. in advanced classes in quantum mechanics and condensed matter physics. In addition, it clarifies the actual role of the gauge in the Landau level problem, which often appears confusing in the usual derivations provided in textbooks. Finally, we go further by showing that a similar methodology can be made to apply to the more difficult case of a spatially non-uniform magnetic field (where closed analytical results are rare), in which case the various generators (pseudomomentum and pseudo-angular momentum) appear as line integrals of the inhomogeneous magnetic field; we give closed analytical solutions for all cases, and show how the old and rather forgotten Bawin-Burnel gauge shows up naturally as a ‘reference gauge’ in all solutions.

  14. The long-term dynamics of mortality benefits from improved water and sanitation in less developed countries.

    Science.gov (United States)

    Jeuland, Marc A; Fuente, David E; Ozdemir, Semra; Allaire, Maura C; Whittington, Dale

    2013-01-01

    The problem of inadequate access to water, sanitation and hygiene (WASH) in less-developed nations has received much attention over the last several decades (most recently in the Millennium Development Goals), largely because diseases associated with such conditions contribute substantially to mortality in poor countries. We present country-level projections for WASH coverage and for WASH-related mortality in developing regions over a long time horizon (1975-2050) and provide dynamic estimates of the economic value of potential reductions in this WASH-related mortality, which go beyond the static results found in previous work. Over the historical period leading up to the present, our analysis shows steady and substantial improvements in WASH coverage and declining mortality rates across many developing regions, namely East Asia and the Pacific, Latin America and the Caribbean, Eastern Europe and the Middle East. The economic value of potential health gains from eliminating mortality attributable to poor water and sanitation has decreased substantially, and in the future will therefore be modest in these regions. Where WASH-related deaths remain high (in parts of South Asia and much of Sub-Saharan Africa), if current trends continue, it will be several decades before economic development and investments in improved water and sanitation will result in the capture of these economic benefits. The fact that health losses will likely remain high in these two regions over the medium term suggests that accelerated efforts are needed to improve access to water and sanitation, though the costs and benefits of such efforts in specific locations should be carefully assessed.

  15. Trial-to-trial dynamics of selective long-term-memory retrieval with continuously changing retrieval targets.

    Science.gov (United States)

    Kizilirmak, Jasmin M; Rösler, Frank; Khader, Patrick H

    2014-10-01

    How do we control the successive retrieval of behaviorally relevant information from long-term memory (LTM) without being distracted by other potential retrieval targets associated to the same retrieval cues? Here, we approach this question by investigating the nature of trial-by-trial dynamics of selective LTM retrieval, i.e., in how far retrieval in one trial has detrimental or facilitatory effects on selective retrieval in the following trial. Participants first learned associations between retrieval cues and targets, with one cue always being linked to three targets, forming small associative networks. In successive trials, participants had to access either the same or a different target belonging to either the same or a different cue. We found that retrieval times were faster for targets that had already been relevant in the previous trial, with this facilitatory effect being substantially weaker when the associative network changed in which the targets were embedded. Moreover, staying within the same network still had a facilitatory effect even if the target changed, which became evident in a relatively higher memory performance in comparison to a network change. Furthermore, event-related brain potentials (ERPs) showed topographically and temporally dissociable correlates of these effects, suggesting that they result from combined influences of distinct processes that aid memory retrieval when relevant and irrelevant targets change their status from trial to trial. Taken together, the present study provides insight into the different processing stages of memory retrieval when fast switches between retrieval targets are required. Copyright © 2014 Elsevier Inc. All rights reserved.

  16. The long-term dynamics of mortality benefits from improved water and sanitation in less developed countries.

    Directory of Open Access Journals (Sweden)

    Marc A Jeuland

    Full Text Available The problem of inadequate access to water, sanitation and hygiene (WASH in less-developed nations has received much attention over the last several decades (most recently in the Millennium Development Goals, largely because diseases associated with such conditions contribute substantially to mortality in poor countries. We present country-level projections for WASH coverage and for WASH-related mortality in developing regions over a long time horizon (1975-2050 and provide dynamic estimates of the economic value of potential reductions in this WASH-related mortality, which go beyond the static results found in previous work. Over the historical period leading up to the present, our analysis shows steady and substantial improvements in WASH coverage and declining mortality rates across many developing regions, namely East Asia and the Pacific, Latin America and the Caribbean, Eastern Europe and the Middle East. The economic value of potential health gains from eliminating mortality attributable to poor water and sanitation has decreased substantially, and in the future will therefore be modest in these regions. Where WASH-related deaths remain high (in parts of South Asia and much of Sub-Saharan Africa, if current trends continue, it will be several decades before economic development and investments in improved water and sanitation will result in the capture of these economic benefits. The fact that health losses will likely remain high in these two regions over the medium term suggests that accelerated efforts are needed to improve access to water and sanitation, though the costs and benefits of such efforts in specific locations should be carefully assessed.

  17. Long-term dynamics of a high-latitude coral reef community at Sodwana Bay, South Africa

    Science.gov (United States)

    Porter, S. N.; Schleyer, M. H.

    2017-06-01

    Dynamics in reef cover, mortality and recruitment success of a high-latitude coral community in South Africa were studied over 20 yr with the aim to detect the effects of climate change. Coral communities at this locality are the southernmost on the African continent, non-accretive, attain high biodiversity and are dominated by soft corals. Long-term monitoring within fixed transects on representative reef was initiated in 1993 and has entailed annual photo-quadrat surveys and hourly temperature logging. Although sea temperatures rose by 0.15 °C p.a. at the site up to 2000, they have subsequently been decreasing, and the overall trend based on monthly means has been a significant decrease of 0.03 °C p.a. Despite this, minor bleaching was encountered in the region during the 1998 El Niño-Southern Oscillation event, again in the summer of 2000/2001 and in 2005. A significant decreasing trend of 0.95% p.a. in soft coral cover has been evident throughout the monitoring period, attributable to significant decreases in Sinularia and Lobophytum spp. cover. In contrast, hard coral cover gradually and significantly increased up to 2005, this being largely attributable to increases in cover by Acropora spp. Recruitment success and mortality of both soft and hard corals has displayed high inter-annual variability with increasing but non-significant trends in the last 5 yr. The reduction in soft coral cover has been more consistent and greater than that of hard corals, but it is difficult at this stage to attribute this to changes in water quality, acidification-linked accretion or temperature.

  18. Dynamics of COX-2 Content in Mucosa of the Stomach and Duodenum on the Background of Medical Correction of NSAID Gastropathy

    Directory of Open Access Journals (Sweden)

    Yu.M. Stepanov

    2013-02-01

    Full Text Available The results of immune histochemical study of cyclooxygenase type 2 (COX-2 level in 120 patients with inflammatory and erosive lesions of the stomach and duodenum on the background of long-term use of non-steroid anti-inflammatory drugs (NSAIDs before and after treatment of damages of gastroduodenal zone are presented. Average level of COX-2 in patients with gastroduodenal lesions, caused by NSAIDs, decreased by 1.5 times and made up (2.02 ± 0.11 c.u. before treatment and (1.27 ± 0.09 c.u after treatment by the regimen № 1; it decreased by 2 times and made up (2.00 ± 0.16 c.u and (0.95 ± 0.09 c.u. relatively before and after the treatment by regimen № 2. Findings indicate the decrease of protective properties of the stomach and duodenum mucosa in case of a long-term use of NSAIDs.

  19. Dynamical downscaling with the fifth-generation Canadian regional climate model (CRCM5) over the CORDEX Arctic domain: effect of large-scale spectral nudging and of empirical correction of sea-surface temperature

    Science.gov (United States)

    Takhsha, Maryam; Nikiéma, Oumarou; Lucas-Picher, Philippe; Laprise, René; Hernández-Díaz, Leticia; Winger, Katja

    2017-10-01

    As part of the CORDEX project, the fifth-generation Canadian Regional Climate Model (CRCM5) is used over the Arctic for climate simulations driven by reanalyses and by the MPI-ESM-MR coupled global climate model (CGCM) under the RCP8.5 scenario. The CRCM5 shows adequate skills capturing general features of mean sea level pressure (MSLP) for all seasons. Evaluating 2-m temperature (T2m) and precipitation is more problematic, because of inconsistencies between observational reference datasets over the Arctic that suffer of a sparse distribution of weather stations. In our study, we additionally investigated the effect of large-scale spectral nudging (SN) on the hindcast simulation driven by reanalyses. The analysis shows that SN is effective in reducing the spring MSLP bias, but otherwise it has little impact. We have also conducted another experiment in which the CGCM-simulated sea-surface temperature (SST) is empirically corrected and used as lower boundary conditions over the ocean for an atmosphere-only global simulation (AGCM), which in turn provides the atmospheric lateral boundary conditions to drive the CRCM5 simulation. This approach, so-called 3-step approach of dynamical downscaling (CGCM-AGCM-RCM), which had considerably improved the CRCM5 historical simulations over Africa, exhibits reduced impact over the Arctic domain. The most notable positive effect over the Arctic is a reduction of the T2m bias over the North Pacific Ocean and the North Atlantic Ocean in all seasons. Future projections using this method are compared with the results obtained with the traditional 2-step dynamical downscaling (CGCM-RCM) to assess the impact of correcting systematic biases of SST upon future-climate projections. The future projections are mostly similar for the two methods, except for precipitation.

  20. Biogeochemical cycles of Chernobyl-born radionuclides in the contaminated forest ecosystems: long-term dynamics of the migration processes

    Science.gov (United States)

    Shcheglov, Alexey; Tsvetnova, Ol'ga; Klyashtorin, Alexey

    2013-04-01

    Biogeochemical migration is a dominant factor of the radionuclide transport through the biosphere. In the early XX century, V.I. Vernadskii, a Russian scientist known, noted about a special role living things play in transport and accumulation of natural radionuclide in various environments. The role of biogeochemical processes in migration and redistribution of technogenic radionuclides is not less important. In Russia, V. M. Klechkovskii and N.V. Timofeev-Ressovskii showed some important biogeochemical aspects of radionuclide migration by the example of global fallout and Kyshtym accident. Their followers, R.M. Alexakhin, M.A. Naryshkin, N.V. Kulikov, F.A. Tikhomirov, E.B. Tyuryukanova, and others also contributed a lot to biogeochemistry of radionuclides. In the post-Chernobyl period, this area of knowledge received a lot of data that allowed building the radioactive element balance and flux estimation in various biogeochemical cycles [Shcheglov et al., 1999]. Regrettably, many of recent radioecological studies are only focused on specific radionuclide fluxes or pursue some applied tasks, missing the holistic approach. Most of the studies consider biogeochemical fluxes of radioactive isotopes in terms of either dose estimation or radionuclide migration rates in various food chains. However, to get a comprehensive picture and develop a reliable forecast of environmental, ecological, and social consequences of radioactive pollution in a vast contaminated area, it is necessary to investigate all the radionuclide fluxes associated with the biogeochemical cycles in affected ecosystems. We believe such an integrated approach would be useful to study long-term environmental consequences of the Fukushima accident as well. In our long-term research, we tried to characterize the flux dynamics of the Chernobyl-born radionuclides in the contaminated forest ecosystems and landscapes as a part of the integrated biogeochemical process. Our field studies were started in June of

  1. Analyzing the term structure of interest rates using the dynamic Nelson-Siegel model with time-varying parameters

    NARCIS (Netherlands)

    Koopman, S.J.; Mallee, M.I.P.; van der Wel, M.

    2010-01-01

    In this article we introduce time-varying parameters in the dynamic Nelson-Siegel yield curve model for the simultaneous analysis and forecasting of interest rates of different maturities. The Nelson-Siegel model has been recently reformulated as a dynamic factor model with vector autoregressive

  2. Dynamics of Gauge Fields at High Temperature

    NARCIS (Netherlands)

    Nauta, B.J.

    2000-01-01

    An effective description of dynamical Bose fields is provided by the classical (high-temperature) limit of thermal field theory. The main subject of this thesis is to improve the ensuing classical field theory, that is, to include the dominant quantum corrections and to add counter terms for the

  3. Long-term dynamics of the state of the fouling community in the Odessa Bay (Black Sea

    Directory of Open Access Journals (Sweden)

    A. Y. Varigin

    2017-04-01

    Full Text Available This article examines the long-term dynamics of the qualitative and quantitative characteristics of the coastal fouling community of OdessaBay(Black Sea for the last 40 years. It compares the data on this community obtained by different researchers in 1976, 1994 and 2016 . The number of species included in the fouling community decreased from 103 (1976 to 43 (1994 and then rose to 62 by 2016. As a possible reason for this reduction in the species composition of the community the influence of large-scale anthropogenic eutrophication, which was already strongly evident in the north-western part of the Black Seain the 1970s, is proposed. This phenomenon was accompanied by periodic outbreaks of mass abundance of planktonic algae, secondary water pollution, the development of hypoxia and a frequent suffocation effect on the benthos, which caused the disappearance from the community of 41 species of invertebrates. The reduction in the number of species affected representatives of the following taxons: Polychaeta, Amphipoda, Gastropoda and Bivalvia. Currently, the core of the community includes the same species of invertebrates as in the past. It is based on Bivalvia mussels Mytilus galloprovincialis. Among the attached forms , Mytilaster lineatus (Bivalvia and Amphibalanus improvisus (Cirripedia play a leading role, and among mobile – representatives of Polychaeta, Isopoda, Amphipoda and Gastropoda. It is shown that 10 of the 25 species, recorded the first time for this community in the 1970s, have become abundant in modern conditions. The primacy in the relative density in the composition of the community at the present time has passed from the amphipod crustaceans to bivalve molluscs. The highest relative biomass, both in the past and in the present-day conditions was observed in representatives of Bivalvia. The structure of the resistance of the fouling community to the effects of unstable environmental factors specific to the coastal zone is

  4. Population Dynamics and Cost-Benefit Analysis. An Attempt to Relate Population Dynamics via Lifetime Reproductive Success to Short-Term Decisions

    NARCIS (Netherlands)

    Tinbergen, J.M.; Balen, J.H. van; Drent, P.J.; Cavé, A.J.; Mertens, J.A.L.; Boer-Hazewinkel, J. den

    1987-01-01

    1. The aim of this article is to explore whether cost-benefit analysis of behaviour may help to understand the population dynamics of a species. The Great Tit is taken as an example. 2. The lifetime reproductive success in different populations of Great Tits amounts from 0.7 (Hoge Veluwe, Wytham) to

  5. Sorting chromatic sextupoles for easily and effectively correcting second order chromaticity in the Relativistic Heavy Ion Collider

    International Nuclear Information System (INIS)

    Luo, Y.; Tepikian, S.; Fischer, W.; Robert-Demolaize, G.; Trbojevic, D.

    2009-01-01

    Based on the contributions of the chromatic sextupole families to the half-integer resonance driving terms, we discuss how to sort the chromatic sextupoles in the arcs of the Relativistic Heavy Ion Collider (RHIC) to easily and effectively correct the second order chromaticities. We propose a method with 4 knobs corresponding to 4 pairs of chromatic sextupole families to online correct the second order chromaticities. Numerical simulation justifies this method, showing that this method reduces the unbalance in the correction strengths of sextupole families and avoids the reversal of sextupole polarities. Therefore, this method yields larger dynamic apertures for the proposed RHIC 2009 100GeV polarized proton run lattices

  6. On the dynamics of k-essence models

    International Nuclear Information System (INIS)

    Jorge, Pedro; Mimoso, Jose P; Wands, David

    2007-01-01

    We investigate cosmological dynamics of models with higher-order corrections to the canonical (second-order) kinetic lagrangian for a scalar field, which have been termed k -essence . We study the qualitative dynamics of simple purely kinetic k-essence models and find that the simplest attempts to construct non-singular cosmological models by including higher-order terms in the kinetic lagrangian fail because of a different type of singularity where the scalar field theory becomes ill-defined

  7. Identifying attachment ruptures underlying severe music performance anxiety in a professional musician undertaking an assessment and trial therapy of Intensive Short-Term Dynamic Psychotherapy (ISTDP).

    Science.gov (United States)

    Kenny, Dianna T; Arthey, Stephen; Abbass, Allan

    2016-01-01

    Kenny has proposed that severe music performance anxiety that is unresponsive to usual treatments such as cognitive-behaviour therapy may be one manifestation of unresolved attachment ruptures in early life. Intensive Short-Term Dynamic Psychotherapy specifically targets early relationship trauma. Accordingly, a trial of Intensive Short-Term Dynamic Psychotherapy with severely anxious musicians was implemented to assess whether resolution of attachment ruptures resulted in clinically significant relief from music performance anxiety. Volunteer musicians participating in a nationally funded study were screened for MPA severity. Those meeting the critical cut-off score on the Kenny Music Performance Anxiety Inventory were offered a trial of Intensive Short-Term Dynamic Psychotherapy. In this paper, we present the theoretical foundations and rationale for the treatment approach, followed by sections of a verbatim transcript and process analysis of the assessment phase of treatment that comprised a 3-h trial therapy session. The 'case' was a professional orchestral musician (male, aged 55) who had suffered severe music performance anxiety over the course of his entire career, which spanned more than 30 years at the time he presented for treatment following his failure to secure a position at audition. The participant was able to access the pain, rage and grief associated with unresolved attachment ruptures with both parents that demonstrated the likely nexus between early attachment trauma and severe music performance anxiety. Intensive Short-Term Dynamic Psychotherapy is a potentially cost-effective treatment for severe music performance anxiety. Further research using designs with higher levels of evidence are required before clinical recommendations can be made for the use of this therapy with this population.

  8. Multisoliton solutions in terms of double Wronskian determinant for a generalized variable-coefficient nonlinear Schroedinger equation from plasma physics, arterial mechanics, fluid dynamics and optical communications

    International Nuclear Information System (INIS)

    Lue Xing; Zhu Hongwu; Yao Zhenzhi; Meng Xianghua; Zhang Cheng; Zhang Chunyi; Tian Bo

    2008-01-01

    In this paper, the multisoliton solutions in terms of double Wronskian determinant are presented for a generalized variable-coefficient nonlinear Schroedinger equation, which appears in space and laboratory plasmas, arterial mechanics, fluid dynamics, optical communications and so on. By means of the particularly nice properties of Wronskian determinant, the solutions are testified through direct substitution into the bilinear equations. Furthermore, it can be proved that the bilinear Baecklund transformation transforms between (N - 1)- and N-soliton solutions

  9. Nonlinear Recurrent Dynamics and Long-Term Nonstationarities in EEG Alpha Cortical Activity: Implications for Choosing Adequate Segment Length in Nonlinear EEG Analyses.

    Science.gov (United States)

    Cerquera, Alexander; Vollebregt, Madelon A; Arns, Martijn

    2018-03-01

    Nonlinear analysis of EEG recordings allows detection of characteristics that would probably be neglected