WorldWideScience

Sample records for dubnium 259

  1. Discovery of fermium-259

    CERN Document Server

    Hoffman, D C; Landrum, J H; Lougheed, R W; Weber, J; Wild, J F; Wilhelmy, J B

    1976-01-01

    A 1.5-sec spontaneous fission activity has been produced by irradiation of /sup 257/Fm with 16-MeV tritons at the Los Alamos Tandem Van de Graaff Facility. On the basis of cross section and fission systematics, this 1.5-sec activity has been attributed to /sup 259/Fm formed by the reaction, /sup 257/Fm(t, p)/sup 259/Fm. /sup 259 /Fm is the heaviest known isotope of fermium and has more neutrons than any other isotope so far identified. The mass distribution of the /sup 259/Fm is highly symmetric and the average total kinetic energy is very high, 230+or-2 MeV. These features continue the trend toward more symmetric mass distributions and higher total kinetic energies observed previously for the fermium isotopes as the number of neutrons is increased. (8 refs).

  2. 16 CFR 259.1 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Definitions. 259.1 Section 259.1 Commercial Practices FEDERAL TRADE COMMISSION GUIDES AND TRADE PRACTICE RULES GUIDE CONCERNING FUEL ECONOMY ADVERTISING FOR NEW AUTOMOBILES § 259.1 Definitions. For the purposes of this part, the following...

  3. 49 CFR 234.259 - Warning time.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Warning time. 234.259 Section 234.259..., Inspection, and Testing Inspections and Tests § 234.259 Warning time. Each crossing warning system shall be tested for the prescribed warning time at least once every 12 months and when the warning system...

  4. 14 CFR 259.2 - Applicability.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Applicability. 259.2 Section 259.2 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS ENHANCED PROTECTIONS FOR AIRLINE PASSENGERS § 259.2 Applicability. This rule applies to all the...

  5. 14 CFR 259.3 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Definitions. 259.3 Section 259.3 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS ENHANCED PROTECTIONS FOR AIRLINE PASSENGERS § 259.3 Definitions. Certificated air carrier means a...

  6. 16 CFR 259.2 - Advertising disclosures.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Advertising disclosures. 259.2 Section 259.2... ADVERTISING FOR NEW AUTOMOBILES § 259.2 Advertising disclosures. (a) No manufacturer or dealer shall make any express or implied representation in advertising concerning the fuel economy of any new automobile...

  7. Chemical isolation of dubnium (element 105) in fluoride media

    Energy Technology Data Exchange (ETDEWEB)

    Trubert, D.; Naour, C. le; Hussonnois, M.; Brillard, L.; Du, J.F. le [Paris-11 Univ., 91 - Orsay (France). Inst. de Physique Nucleaire Radiochimie; Guzman, F.M. [ININ, Carretera Mexico-Toluca, Ocoyoacac, Estado de Mexico (Mexico); Constantinescu, O. [JINR, Dubna (Russian Federation). Flerov Lab. of Nuclear Reactions; Gasparro, J.; Barci, V.; Weiss, B.; Ardisson, G. [Nice Univ. (France). Lab. de Radiochimie

    2002-07-01

    The isotope {sup 262}Db was produced by irradiation of a {sup 248}Cm target with 106-MeV {sup 19}F ions at the 15 MV MP Tandem accelerator of Orsay (France). The reaction products were continuously and rapidly transported with a KCl aerosol helium jet system to the chemistry setup. They were dissolved in HF medium and the solution was passed through three successive ion exchange columns, allowing a continuous high level purification of Db from actinides on a first cation exchange column, the isolation of Db on an anion exchange one, and the retention of the long-lived decay products of {sup 262}Db (3.24 h-{sup 254}Fm) on a second cation exchange column. Just after the end of irradiation, the decay products were desorbed from this column, purified and {alpha}-sources were prepared on carbon foil by electrospray. In 13 effective irradiation hours, 22 events corresponding to the {alpha}-decay of {sup 254}Fm were recorded. Almost 70 atoms of {sup 262}Db, produced in the reaction {sup 248}Cm + {sup 19}F were isolated in dilute HF medium. Like its homologues/analogues Nb, Ta and Pa, dubnium forms, with fluoride ions, negatively charged complexes which are strongly retained on anion exchanger. (orig.)

  8. 50 CFR 259.32 - Conditional fisheries.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Conditional fisheries. 259.32 Section 259.32 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE AID TO FISHERIES CAPITAL CONSTRUCTION FUND Capital Construction...

  9. 38 CFR 17.259 - Direct costs.

    Science.gov (United States)

    2010-07-01

    ... personnel or for fringe benefits, rent, publications, educational programs, training, research... Exchange of Information § 17.259 Direct costs. Direct costs to which grant funds may be applied may...

  10. Dicty_cDB: CHP259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHP259 (Link to dictyBase) - - - Contig-U16440-1 CHP259P (Link to Original site) CHP...259F 582 CHP259Z 651 CHP259P 1213 - - Show CHP259 Library CH (Link to library) Clone ID CHP...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CH/CHP2-C/CHP259Q.Seq.d/ Representative seq. ID CHP...259P (Link to Original site) Representative DNA sequence >CHP259 (CHP259Q) /CSM/CH/CHP2-C/CHP...nificant alignments: (bits) Value CHP259 (CHP259Q) /CSM/CH/CHP2-C/CHP259Q.Seq.d/

  11. Dicty_cDB: SLB259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLB259 (Link to dictyBase) - - - Contig-U16475-1 SLB259Z (Link... to Original site) - - SLB259Z 684 - - - - Show SLB259 Library SL (Link to library) Clone ID SLB259 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLB2-C/SLB259Q.Seq.d/ Representative seq. ID SLB25...9Z (Link to Original site) Representative DNA sequence >SLB259 (SLB259Q) /CSM/SL/SLB2-C/SLB259Q.Seq.d/ XXXXX...ucing significant alignments: (bits) Value SLB259 (SLB259Q) /CSM/SL/SLB2-C/SLB259

  12. Dicty_cDB: VHI259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available VH (Link to library) VHI259 (Link to dictyBase) - - - Contig-U11746-1 VHI259P (Link to Original site) VHI...259F 449 VHI259Z 200 VHI259P 629 - - Show VHI259 Library VH (Link to library) Clone ID VHI... URL http://dictycdb.biol.tsukuba.ac.jp/CSM/VH/VHI2-C/VHI259Q.Seq.d/ Representative seq. ID VHI...259P (Link to Original site) Representative DNA sequence >VHI259 (VHI259Q) /CSM/VH/VHI2-C/VHI2...nces producing significant alignments: (bits) Value VHI259 (VHI259Q) /CSM/VH/VHI2-C/VHI259Q.Seq.d/ 844 0.0 V

  13. 14 CFR 259.1 - Purpose.

    Science.gov (United States)

    2010-01-01

    ... and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS ENHANCED PROTECTIONS FOR AIRLINE PASSENGERS § 259.1 Purpose. The purpose of this part is to mitigate hardships for airline passengers during lengthy tarmac delays and otherwise to bolster air...

  14. Dicty_cDB: SFJ259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFJ259 (Link to dictyBase) - - - Contig-U16368-1 SFJ259P (Link to Original site) SF...J259F 505 SFJ259Z 702 SFJ259P 1207 - - Show SFJ259 Library SF (Link to library) Clone ID SF...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SF/SFJ2-C/SFJ259Q.Seq.d/ Representative seq. ID SF...J259P (Link to Original site) Representative DNA sequence >SFJ259 (SFJ259Q) /CSM/SF/SFJ2-C/SFJ...AASSAASSESSESSSATS*ik Translated Amino Acid sequence (All Frames) Frame A: hcwptgkfqilftlhsnfviikkgik*lyiyiki*kk*nenfifsfsf

  15. 25 CFR 700.259 - Records subject to Privacy Act.

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 2 2010-04-01 2010-04-01 false Records subject to Privacy Act. 700.259 Section 700.259 Indians THE OFFICE OF NAVAJO AND HOPI INDIAN RELOCATION COMMISSION OPERATIONS AND RELOCATION PROCEDURES Privacy Act § 700.259 Records subject to Privacy Act. The Privacy Act applies to all “records” as...

  16. 14 CFR 259.6 - Notice and contract of carriage.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Notice and contract of carriage. 259.6 Section 259.6 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS ENHANCED PROTECTIONS FOR AIRLINE PASSENGERS § 259.6 Notice and contract of...

  17. 14 CFR 259.5 - Customer service plan.

    Science.gov (United States)

    2010-01-01

    ... customer service from code-share partners; (11) Ensuring responsiveness to customer complaints; and (12... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Customer service plan. 259.5 Section 259.5... REGULATIONS ENHANCED PROTECTIONS FOR AIRLINE PASSENGERS § 259.5 Customer service plan. (a) Adoption of...

  18. Cold Fusion Production and Decay of Neutron-Deficient Isotopes of Dubnium and Development of Extraction Systems for Group V Elements

    Energy Technology Data Exchange (ETDEWEB)

    Gates, Jacklyn M. [Univ. of California, Berkeley, CA (United States)

    2008-07-31

    Excitation functions for the 1n and 2n exit channels of the 208Pb(51V,xn)259-xDb reaction were measured. A maximum cross section of the 1n exit channel of 2070$+1100\\atop{-760}$ pb was measured at an excitation energy of 16.0 ± 1.8 MeV. For the 2n exit channel, a maximum cross section of 1660$+450\\atop{-370}$ pb was measured at 22.0 ± 1.8 MeV excitation energy. The 1n excitation function for the 209Bi(50Ti,n)258Db reaction was remeasured, resulting in a cross section of 5480$+1730\\atop{-1370}$ pb at an excitation energy of 16.0 ± 1.6 MeV. Differences in cross section maxima are discussed in terms of the fusion probability below the barrier. The extraction of niobium (Nb) and tantalum (Ta) from hydrochloric acid and mixed hydrochloric acid/lithium chloride media by bis(2-ethylhexyl) hydrogen phosphate (HDEHP) and bis(2-ethylhexyl) hydrogen phosphite (BEHP) was studied. The goal of the experiments was to find a system that demonstrates selectivity among the members of group five of the Periodic Table and is also suitable for the study of dubnium (Db, Z = 105). Experiments with niobium and tantalum were performed with carrier (10-6 M), carrier free (10-10 M) and trace (10-16 M) concentrations of metal using hydrochloric acid solution with concentrations ranging from 1 - 11 M. The extraction of niobium and tantalum from mixed hydrochloric acid/lithium chloride media by HDEHP and BEHP as a function of hydrogen ion (H+) concentration was also investigated. The data obtained are used as the basis to discuss the speciation of niobium and tantalum under the conditions studied and to evaluate possible extraction mechanisms. The 74Se(18O,p3n)88gNb excitation function was measured to determine the best energy for producing the 88Nb used in chemistry experiments. A maximum cross section of 495 +- 5 mb was observed at an 18O energy of 74.0 Me

  19. Development of an extraction system for the separation of dubnium from rutherfordium using MIBK and HCl/HF solutions

    Energy Technology Data Exchange (ETDEWEB)

    Schumann, Dorothea; Dressler, Rugard [Paul Scherrer Institut (PSI), Villigen (Switzerland)

    2016-04-01

    A chemical separation system was developed to separate group 4 and 5 elements using extraction from HCl/HF solution into methyl-isobutyl-ketone (MIBK). The system is proposed to be applied for a confident assignment of the spontaneous fissioning radionuclide produced as decay product of element 115 either as dubnium (Db, Z = 105) or rutherfordium (Rf, Z = 104). Moreover, extraction systems are proposed allowing the investigation of chemical properties of Db in comparison to the properties of its lighter homologs Nb and Ta.

  20. 50 CFR 216.259 - Modifications to Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... in the Gulf of Mexico § 216.259 Modifications to Letters of Authorization. (a) Except as provided...

  1. 14 CFR 259.7 - Response to consumer problems.

    Science.gov (United States)

    2010-01-01

    ... PROCEEDINGS) ECONOMIC REGULATIONS ENHANCED PROTECTIONS FOR AIRLINE PASSENGERS § 259.7 Response to consumer... department in the airline with which to file a complaint about its scheduled service. This information shall... concerning a difficulty or problem which the person experienced when using or attempting to use an airline's...

  2. 37 CFR 2.59 - Filing substitute specimen(s).

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Filing substitute specimen(s..., DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Drawing § 2.59 Filing substitute specimen(s). (a... specimen(s), the applicant must: (1) For an amendment to allege use under § 2.76, verify by affidavit...

  3. 7 CFR 2.59 - Deputy Under Secretaries for Natural Resources and Environment.

    Science.gov (United States)

    2010-01-01

    ... Environment. 2.59 Section 2.59 Agriculture Office of the Secretary of Agriculture DELEGATIONS OF AUTHORITY BY... Under Secretary for Natural Resources and Environment § 2.59 Deputy Under Secretaries for Natural Resources and Environment. Pursuant to § 2.20(a), subject to reservations in § 2.20(b), and subject...

  4. 29 CFR 779.259 - What is included in annual gross volume.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false What is included in annual gross volume. 779.259 Section... Coverage Annual Gross Volume of Sales Made Or Business Done § 779.259 What is included in annual gross volume. (a) The annual gross volume of sales made or business done of an enterprise consists of its...

  5. 24 CFR 207.259a - Waiver of title objection; mortgages formerly Commissioner-held.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Waiver of title objection; mortgages formerly Commissioner-held. 207.259a Section 207.259a Housing and Urban Development Regulations... title objection; mortgages formerly Commissioner-held. If the Commissioner sells a mortgage and...

  6. AFM quantitative analysis and determination of shear angle of {259}f martensitic surface relief

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    An attentive observation and quantitative analysis of {259}f martensitic surface relief in an Fe-23Ni-0.55C alloy are made by means of an atomic force microscope (AFM), and different martensitic variants' shear angles are determined in this paper. The experiments show that {259}f martensitic surface relief exhibits regular shape in many cases, which is in agreement with the prediction of invariant plane strain (IPS). Generally, {259}f martensitic surface relief appears to be "N"-shaped, but it is tent-shaped in the case of zigzag-shaped martensite. The compressed deformation of parent phase diminishes the surface relief in size but with little change of its relief angle. {259}f martensitic surface relief, large or small, has approximately the same relief angles, exhibiting a good "self-similar fractal". The determined values of different {259}f martensitic variants' shear angles are in fine agreement with the prediction of Wechsler-Liberman-Read (W-L-R) theory, with only a slight difference of less than 3.65°.

  7. Characterization of Group V Dubnium Homologs on DGA Extraction Chromatography Resin from Nitric and Hydrofluoric Acid Matrices

    Energy Technology Data Exchange (ETDEWEB)

    Despotopulos, J D; Sudowe, R

    2012-02-21

    Studies of the chemical properties of superheavy elements (SHE) pose interesting challenges due to their short half-lives and low production rates. Chemical systems must have extremely fast kinetics, fast enough kinetics to be able to examine the chemical properties of interest before the SHE decays to another nuclide. To achieve chemistry on such time scales, the chemical system must also be easily automated. Most importantly however, a chemical system must be developed which provides suitable separation and kinetics before an on-line study of a SHE can be performed. Relativistic effects make studying the chemical properties of SHEs interesting due to the impact these effects could have on the SHEs chemical properties. Relativistic effects arise when the velocity of the s orbital electrons approach the speed of light. As this velocity increases, the Bohr radius of the inner electron orbitals decreases and there is an increase in the particles mass. This contraction results in a destabilization of the energy of the outer d and f electron orbitals (5f and 6d in the case of SHE), which can cause these to expand due to their increased shielding from the nuclear charge. Another relativistic effect is the spin-orbit splitting for p, d, and f orbitals into j = 1 {+-} 1/2 states. This can lead most interestingly to a possible increased stability of element 114, which due to large spin-orbit splitting of the 7p orbital and the relativistically stabilized 7p{sub 1/2} and 7s orbital gives rise to a closed shell ground state of 7s{sup 2}7p{sub 1/2}{sup 2}. The homologs of element 105, dubnium (Db), Ta and Nb and the pseudo-homolog Pa, are well known to hydrolyze and form both neutral and non-neutral monoatomic and polyatomic species that may cause issues with extraction from a given chemical system. Early ion-exchange and solvent-extraction studies show mixed results for the behavior of Db. Some studies show Db behaving most similar to Ta, while others show it behaving

  8. Yeast Interacting Proteins Database: YNL092W, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ey (1) YDR259C YAP6 Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium...ption Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithi...um tolerance; computational analysis suggests a role in regulation of expression of

  9. 20 CFR 1002.259 - How does USERRA protect an employee's pension benefits?

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false How does USERRA protect an employee's pension... REEMPLOYMENT RIGHTS ACT OF 1994 Reemployment Rights and Benefits Pension Plan Benefits § 1002.259 How does USERRA protect an employee's pension benefits? On reemployment, the employee is treated as not having a...

  10. Measurement of the 208Pb(52Cr, n)259Sg Excitation Function

    Energy Technology Data Exchange (ETDEWEB)

    Folden III, C.M.; Dragojevic, I.; Dullmann, Ch.E.; Eichler, R.; Garcia, M.A.; Gates, J.M.; Nelson, S.L.; Sudowe, R.; Gregorich, K.E.; Hoffman, D.C.; Nitsche, H.

    2010-03-19

    The excitation function for the 208Pb(52Cr, n)259Sg reaction has been measured using the Berkeley Gas-filled Separator at the Lawrence Berkeley National Laboratory 88-Inch Cyclotron. The maximum cross section of pb is observed at a center-of-target laboratory-frame energy of 253.0 MeV. In total, 25 decay chains originating from 259Sg were observed and the measured decay properties are in good agreement with previous reports. In addition, a partial excitation function for the 208Pb(52Cr, 2n)258Sg reaction was obtained, and an improved 258Sg half-life of ms was calculated by combining all available experimental data.

  11. The Nucleus of Main-Belt Comet 259P/Garradd

    CERN Document Server

    MacLennan, Eric

    2012-01-01

    We present observations of the main-belt comet 259P/Garradd, previously known as P/2008 R1 (Garradd), obtained in 2011 and 2012 using the Gemini North Telescope on Mauna Kea in Hawaii, and the SOAR Telescope at Cerro Pachon in Chile, with the goal of computing the object's phase function and nucleus size. We find an absolute magnitude of $H_R=19.71\\pm0.05$ mag and slope parameter of $G_R=-0.08\\pm0.05$ for the inactive nucleus, corresponding to an effective nucleus radius of $r_e=0.30\\pm0.02$ km, assuming an $R$-band albedo of $p_R=0.05$. We also revisit observations reported for 259P while it was active in 2008 to quantify the dust mass loss and compare the object with other known main-belt comets.

  12. THE NUCLEUS OF MAIN-BELT COMET 259P/GARRADD

    Energy Technology Data Exchange (ETDEWEB)

    MacLennan, Eric M.; Hsieh, Henry H., E-mail: hsieh@ifa.hawaii.edu, E-mail: emaclenn@utk.edu [Institute for Astronomy, University of Hawaii, 2680 Woodlawn Drive, Honolulu, HI 96822 (United States)

    2012-10-10

    We present observations of the main-belt comet 259P/Garradd, previously known as P/2008 R1 (Garradd), obtained in 2011 and 2012 using the Gemini North Telescope on Mauna Kea in Hawaii and the SOAR telescope at Cerro Pachon in Chile, with the goal of computing the object's phase function and nucleus size. We find an absolute magnitude of H{sub R} = 19.71 {+-} 0.05 mag and slope parameter of G{sub R} = -0.08 {+-} 0.05 for the inactive nucleus, corresponding to an effective nucleus radius of r{sub e} = 0.30 {+-} 0.02 km, assuming an R-band albedo of p{sub R} = 0.05. We also revisit observations reported for 259P while it was active in 2008 to quantify the dust mass loss and compare the object with other known main-belt comets.

  13. Survival of crimes of suspicion: the case of article 259 of the Argentine Penal Code

    OpenAIRE

    2011-01-01

    Los “delitos de sospecha”, se encuentran plenamente vigentes pese a ser tipos manifiestamente inconstitucionales por violar los principios de inocencia, culpabilidad, lesividad, legalidad y de acto. Para demostrar tal afirmación, luego de caracterizar a esta categoría, se verifican sus elementos analizando los delitos de admisión y ofrecimiento de dádivas a funcionarios públicos del artículo 259 del Código penal argentino. The “crimes of suspicion”, are effective totally in spite...

  14. Prognostic factorsin inoperable adenocarcinoma of the lung: A multivariate regression analysis of 259 patiens

    DEFF Research Database (Denmark)

    Sørensen, Jens Benn; Badsberg, Jens Henrik; Olsen, Jens

    1989-01-01

    The prognostic factors for survival in advanced adenocarcinoma of the lung were investigated in a consecutive series of 259 patients treated with chemotherapy. Twenty-eight pretreatment variables were investigated by use of Cox's multivariate regression model, including histological subtypes...... and degree of differentiation, the new international staging system for lung cancer, and seven laboratory parameters. Staging of the patients included bone marrow examination but were otherwise nonextensive without routine bone, liver, and brain scans. Factors predicting poor survival were low performance...... status, stage IV disease, no prior nonradical resection, liver metastases, high values of white blood cell count, and lactate dehydrogenase, and low values of aspartate aminotransaminase. The nonradical resection may not be a prognostic factor because of the resection itself but may rather serve...

  15. Advanced conceptual design report: T Plant secondary containment and leak detection upgrades. Project W-259

    Energy Technology Data Exchange (ETDEWEB)

    Hookfin, J.D.

    1995-05-12

    The T Plant facilities in the 200-West Area of the Hanford site were constructed in the early 1940s to produce nuclear materials in support of national defense activities. T Plant includes the 271-T facility, the 221-T facility, and several support facilities (eg, 2706-T), utilities, and tanks/piping systems. T Plant has been recommended as the primary interim decontamination facility for the Hanford site. Project W-259 will provide capital upgrades to the T Plant facilities to comply with Federal and State of Washington environmental regulations for secondary containment and leak detection. This document provides an advanced conceptual design concept that complies with functional requirements for the T Plant Secondary Containment and Leak Detection upgrades.

  16. The role of Glu259 in Escherichia coli elongation factor Tu in ternary complex formation

    DEFF Research Database (Denmark)

    Nautrup Pedersen, Gitte; Rattenborg, Thomas; Knudsen, Charlotte Rohde;

    1998-01-01

    Determination of the crystal structure of the ternary complex formed between elongation factor Tu:GTP and aminoacylated tRNA revealed three regions of interaction between elongation factor Tu and tRNA. The structure indicates that the conserved glutamic acid at position 271 in Thermus aquaticus EF......-Tu could be involved in the binding of the 3' CCA-Phe end of the aminoacylated tRNA. Therefore, the corresponding residue, Glu259, of Escherichia coli EF-Tu was mutated into alanine, aspartic acid, glutamine and tyrosine, in order to substantiate the crystallographic structural evidence and to obtain...... of interaction with tRNA, while mutation to tyrosine abolished completely the interaction with tRNA. Finally, mutation to glutamine resulted in an elongation factor Tu variant behaving like the wild type. In conclusion, the environment around the site binding the CCA-Phe end of the tRNA is very restricted...

  17. Residue 259 in protein-tyrosine phosphatase PTP1B and PTPα determines the flexibility of glutamine 262

    DEFF Research Database (Denmark)

    Peters, Günther H.j.; Iversen, L.F.; Andersen, H.S.

    2004-01-01

    To study the flexibility of the substrate-binding site and in particular of Gln262, we have performed adiabatic conformational search and molecular dynamics simulations on the crystal structure of the catalytic domain of wild-type protein-tyrosine phosphatase (PTP) 1B, a mutant PTP1B(R47V),(D48N...... and second step of the phosphate hydrolysis. Analyses of the trajectories revealed that in the cysteine-phosphor complex of PTP1B, Gln262 oscillates freely between the bound phosphate group and Gly259 frequently forming, as observed in the crystal structure, a hydrogen bond with the backbone oxygen of Gly259...

  18. 17 CFR 259.5s - Form U5S, for annual reports filed under section 5(c) of the Act.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form U5S, for annual reports filed under section 5(c) of the Act. 259.5s Section 259.5s Commodity and Securities Exchanges SECURITIES... 1935 Forms for Registration and Annual Supplements § 259.5s Form U5S, for annual reports filed under...

  19. The Lyα reference sample. I. Survey outline and first results for Markarian 259

    Energy Technology Data Exchange (ETDEWEB)

    Östlin, Göran; Hayes, Matthew; Duval, Florent; Sandberg, Andreas; Rivera-Thorsen, Thøger; Marquart, Thomas; Adamo, Angela; Melinder, Jens; Guaita, Lucia; Micheva, Genoveva [Department of Astronomy, Stockholm University, Oscar Klein Centre, AlbaNova, Stockholm SE-106 91 (Sweden); Orlitová, Ivana [Observatoire de Genève, Université de Genève, Chemin des Maillettes 51, 1290 Versoix (Switzerland); Atek, Hakim [Laboratoire d' Astrophysique, Ecole Polytechnique Fédérale de Lausanne, Observatoire de Sauverny, CH-1290 Versoix (Switzerland); Cannon, John M.; Pardy, Stephen A. [Department of Physics and Astronomy, Macalester College, 1600 Grand Avenue, Saint Paul, MN 55105 (United States); Gruyters, Pieter [Department of Physics and Astronomy, Division of Astronomy and Space Physics, Uppsala University, Box 516, 75120 Uppsala (Sweden); Herenz, Edmund Christian [Leibniz-Institute for Astrophysics Potsdam (AIP), innoFSPEC, An der Sternwarte 16, D-14482 Potsdam (Germany); Kunth, Daniel [Institut d' Astrophysique Paris, 98bis Bd Arago, F-75014 Paris (France); Laursen, Peter [Dark Cosmology Centre, Niels Bohr Institute, University of Copenhagen, DK-2100 Copenhagen (Denmark); Mas-Hesse, J. Miguel [Centro de Astrobiologa (CSIC-INTA), Departamento de Astrofsica, POB 78, E-28691, Villanueva de la Cañada (Spain); Otí-Floranes, Héctor [Instituto de Astronoma, Universidad Nacional Autnoma de Mxico, Apdo. Postal 106, Ensenada B. C. 22800 (Mexico); and others

    2014-12-10

    The Lyα Reference Sample (LARS) is a substantial program with the Hubble Space Telescope (HST) that provides a sample of local universe laboratory galaxies in which to study the detailed astrophysics of the visibility and strength of the Lyαline of neutral hydrogen. Lyα is the dominant spectral line in use for characterizing high-redshift (z) galaxies. This paper presents an overview of the survey, its selection function, and HST imaging observations. The sample was selected from the combined GALEX+Sloan Digital Sky Survey catalog at z = 0.028-0.19, in order to allow Lyα to be captured with combinations of long-pass filters in the Solar Blind Channel (SBC) of the Advanced Camera for Surveys (ACS) onboard HST. In addition, LARS utilizes Hα and Hβ narrowband and u, b, i broadband imaging with ACS and the Wide Field Camera 3 (WFC3). In order to study galaxies in which large numbers of Lyα photons are produced (whether or not they escape), we demanded an Hα equivalent width W(Hα) ≥100 Å. The final sample of 14 galaxies covers far-UV (FUV, λ ∼ 1500 Å) luminosities that overlap with those of high-z Lyα emitters (LAEs) and Lyman break galaxies (LBGs), making LARS a valid comparison sample. We present the reduction steps used to obtain the Lyα images, including our LARS eXtraction software (LaXs), which utilizes pixel-by-pixel spectral synthesis fitting of the energy distribution to determine and subtract the continuum at Lyα. We demonstrate that the use of SBC long-pass-filter combinations increase the signal-to-noise ratio by an order of magnitude compared to the nominal Lyα filter available in SBC. To exemplify the science potential of LARS, we also present some first results for a single galaxy, Mrk 259 (LARS #1). This irregular galaxy shows bright and extended (indicative of resonance scattering) but strongly asymmetric Lyα emission. Spectroscopy from the Cosmic Origins Spectrograph on board HST centered on the brightest UV knot shows a moderate

  20. Novel phosphorylation of aquaporin-5 at its threonine 259 through cAMP signaling in salivary gland cells.

    Science.gov (United States)

    Hasegawa, Takahiro; Azlina, Ahmad; Javkhlan, Purevjav; Yao, Chenjuan; Akamatsu, Tetsuya; Hosoi, Kazuo

    2011-09-01

    Aquaporin-5 (AQP5), a water channel, plays key roles in salivary secretion. The novel phosphorylation of AQP5 was investigated by using human salivary gland (HSG) cells and mouse salivary glands. In the HSG cells stably transfected with a wild-type mouse AQP5 construct, a protein band immunoreactive with antibody against phosphorylated PKA substrate was detected in the AQP5 immunoprecipitated sample, and its intensity was enhanced by short-term treatment of the cells with 8-bromo-cAMP, forskolin, or phorbol 12-myristate 13-acetate, but not by that with A23187 calcium ionophore. Such enhancement was inhibited in the presence of H-89, a PKA inhibitor. An AQP5 mutant (AQP5-T259A) expressed by transfection of HSG cells was not recognized by anti-phosphorylated PKA substrate antibody, even when the cells were stimulated with the protein kinase activators. Immunoblotting and immunofluorescence studies using a specific antibody detecting AQP5 phosphorylated at its Thr259 demonstrated that AQP5 was rapidly and transiently phosphorylated at the apical membrane of acinar cells in the submandibular and parotid glands after administration of isoproterenol, but not pilocarpine. Furthermore, both AQP5 and AQP5-T259A were constitutively localized at the plasma membrane in HSG cells under the resting and forskolin-stimulated conditions. These results suggest that AQP5 is phosphorylated at its Thr259 by PKA through cAMP, but not Ca(2+), signaling pathways, and that this phosphorylation does not contribute to AQP5 trafficking in the salivary gland cells.

  1. Fragrance material review on methyl-2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone.

    Science.gov (United States)

    Scognamiglio, J; Letizia, C S; Api, A M

    2013-12-01

    A toxicologic and dermatologic review of methyl 2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone when used as a fragrance ingredient is presented. Methyl 2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone is a member of the fragrance structural group Alkyl Cyclic Ketones. These fragrances can be described as being composed of an alkyl, R1, and various substituted and bicyclic saturated or unsaturated cyclic hydrocarbons, R2, in which one of the rings may include up to 12 carbons. Alternatively, R2 may be a carbon bridge of C2-C4 carbon chain length between the ketone and cyclic hydrocarbon. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. Available data for methyl 2,6,10-trimethylcyclododeca-2,5,9-trien-1-yl ketone were evaluated then summarized and includes physical properties, acute toxicity, skin irritation, mucous membrane (eye) irritation, skin sensitization, repeated dose, and genotoxicity data. A safety assessment of the entire Alkyl Cyclic Ketones will be published simultaneously with this document; please refer to Belsito et al. (Belsito, D., Bickers, D., Bruze, M., Calow, P., Dagli, M., Fryer, A.D., Greim, H., Miyachi, Y., Saurat, J.H., Sipes, I.G., 2013. A Toxicologic and Dermatologic Assessment of Alkyl Cyclic Ketones When Used as Fragrance Ingredients (submitted for publication)) for an overall assessment of the safe use of this material and all Alkyl Cyclic Ketones in fragrances. Copyright © 2013 Elsevier Ltd. All rights reserved.

  2. Measurement of the Erc .m .=259 keV resonance in the 14N(p ,γ )15O reaction

    Science.gov (United States)

    Daigle, S.; Kelly, K. J.; Champagne, A. E.; Buckner, M. Q.; Iliadis, C.; Howard, C.

    2016-08-01

    The 14N(p ,γ )15O reaction regulates the power generated by the CN cycle and thus impacts the structure and evolution of every star at some point in its life. The lowest positive-energy resonance in this reaction is located at Erc .m .=259 keV, too high in energy to strongly influence quiescent stellar burning. However, the strength of this resonance is used as a cross-section normalization for lower-energy measurements of this reaction. We report on new measurements of the energy, strength, and γ -ray branching ratios for the 259-keV resonance, using different detection and data-analysis schemes. We have also reevaluated previous results, where possible. Our new recommended strength of ω γ =12.6 (3 ) meV is in agreement with the previous value of 13.1(6) meV, but is more precise and thus provides a more reliable normalization for low-energy (p ,γ ) measurements.

  3. Characterization of the constituents and antioxidant activity of Brazilian green tea (Camellia sinensis var. assamica IAC-259 cultivar) extracts.

    Science.gov (United States)

    Saito, Samuel T; Gosmann, Grace; Saffi, Jenifer; Presser, Márcio; Richter, Marc F; Bergold, Ana M

    2007-11-14

    Freeze-dried extracts from Camellia sinensis var. assamica IAC-259 cultivar named Brazilian green tea were prepared by hot water and ultrasound-assisted extractions using leaves harvested in spring and summer. Their caffeine and catechin contents were measured by high performance liquid chromatography-diode array detector. The antioxidant activity of the major green tea compounds and Brazilian green tea extracts was evaluated using a 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. The levels of caffeine were higher in the summer samples (p extract not only epigallocatechin gallate but also epicatechin gallate (p Antioxidant activities of the Brazilian green tea extracts were not significantly different among seasons and extraction systems. The antioxidant data (IC50) of the Brazilian green tea extracts showed a significant correlation with their epigallocatechin gallate and epicatechin gallate contents (p < 0.05).

  4. 40 CFR 264.259 - Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27.

    Science.gov (United States)

    2010-07-01

    ... HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.259 Special requirements for hazardous wastes FO20, FO21, FO22, FO23, FO26, and FO27. (a) Hazardous Wastes FO20, FO21, FO22, FO23, FO26... with these wastes; and (4) The effectiveness of additional treatment, design, or monitoring techniques...

  5. 17 CFR 259.5a - Form U5A, for notification of registration filed under section 5(a) of the Act.

    Science.gov (United States)

    2010-04-01

    ...: For Federal Register citations affecting Form U5A, see the List of CFR Sections Affected, which... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Form U5A, for notification of... OF 1935 Forms for Registration and Annual Supplements § 259.5a Form U5A, for notification...

  6. Selected Bibliography (259 ref.) of Ojibwa and Other Native American Related Research Concerning Psychoeducational Assessment and Intervention (as well as Related Historical, Cultural, Legal, Economic, and Medical Factors).

    Science.gov (United States)

    McShane, Damian, Comp.

    Utilizing ERIC (Educational Resources Information Center), DAI (Dissertation Abstracts International), and APA (American Psychological Association) computer search resources and library resources in Tennessee, Minnesota, Wisconsin, and Canada, this bibliography contains 259 citations pertaining to Ojibwa (Chippewa) and other Native Americans.…

  7. Function of RSKS-1-AAK-2-DAF-16 signaling cascade in enhancing toxicity of multi-walled carbon nanotubes can be suppressed by mir-259 activation in Caenorhabditis elegans

    Science.gov (United States)

    Zhuang, Ziheng; Li, Min; Liu, Hui; Luo, Libo; Gu, Weidong; Wu, Qiuli; Wang, Dayong

    2016-08-01

    Caenorhabditis elegans is an important non-mammalian alternative assay model for toxicological study. Previous study has indicated that exposure to multi-walled carbon nanotubes (MWCNTs) dysregulated the transcriptional expression of mir-259. In this study, we examined the molecular basis for mir-259 in regulating MWCNTs toxicity in nematodes. Mutation of mir-259 induced a susceptible property to MWCNTs toxicity, and MWCNTs exposure induced a significant increase in mir-259::GFP in pharyngeal/intestinal valve and reproductive tract, implying that mir-259 might mediate a protection mechanisms for nematodes against MWCNTs toxicity. RSKS-1, a putative ribosomal protein S6 kinase, acted as the target for mir-259 in regulating MWCNTs toxicity, and mutation of rsks-1 suppressed the susceptible property of mir-259 mutant to MWCNTs toxicity. Moreover, mir-259 functioned in pharynx-intestinal valve and RSKS-1 functioned in pharynx to regulate MWCNTs toxicity. Furthermore, RSKS-1 regulated MWCNTs toxicity by suppressing the function of AAK-2-DAF-16 signaling cascade. Our results will strengthen our understanding the microRNAs mediated protection mechanisms for animals against the toxicity from certain nanomaterials.

  8. Acute Uncomplicated Febrile Illness in Children Aged 2-59 months in Zanzibar - Aetiologies, Antibiotic Treatment and Outcome.

    Directory of Open Access Journals (Sweden)

    Kristina Elfving

    Full Text Available Despite the fact that a large proportion of children with fever in Africa present at primary health care facilities, few studies have been designed to specifically study the causes of uncomplicated childhood febrile illness at this level of care, especially in areas like Zanzibar that has recently undergone a dramatic change from high to low malaria transmission.We prospectively studied the aetiology of febrile illness in 677 children aged 2-59 months with acute uncomplicated fever managed by IMCI (Integrated Management of Childhood Illness guidelines in Zanzibar, using point-of-care tests, urine culture, blood-PCR, chest X-ray (CXR of IMCI-pneumonia classified patients, and multiple quantitative (qPCR investigations of nasopharyngeal (NPH (all patients and rectal (GE swabs (diarrhoea patients. For comparison, we also performed NPH and GE qPCR analyses in 167 healthy community controls. Final fever diagnoses were retrospectively established based on all clinical and laboratory data. Clinical outcome was assessed during a 14-day follow-up. The utility of IMCI for identifying infections presumed to require antibiotics was evaluated.NPH-qPCR and GE-qPCR detected ≥1 pathogen in 657/672 (98% and 153/164 (93% of patients and 158/166 (95% and 144/165 (87% of controls, respectively. Overall, 57% (387/677 had IMCI-pneumonia, but only 12% (42/342 had CXR-confirmed pneumonia. Two patients were positive for Plasmodium falciparum. Respiratory syncytial virus (24.5%, influenza A/B (22.3%, rhinovirus (10.5% and group-A streptococci (6.4%, CXR-confirmed pneumonia (6.2%, Shigella (4.3% were the most common viral and bacterial fever diagnoses, respectively. Blood-PCR conducted in a sub-group of patients (n = 83 without defined fever diagnosis was negative for rickettsiae, chikungunya, dengue, Rift Valley fever and West Nile viruses. Antibiotics were prescribed to 500 (74% patients, but only 152 (22% had an infection retrospectively considered to require

  9. Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3ζ dimer.

    Science.gov (United States)

    Molzan, Manuela; Ottmann, Christian

    2012-11-02

    C-RAF kinase is a central component of the Ras-RAF-MEK (mitogen-activated protein kinase/extracellular signal-regulated kinase)-ERK (extracellular signal-regulated kinase) pathway, which has been shown to be activated in 30% of human tumors. 14-3-3 proteins inactivate C-RAF by binding to the two N-terminal phosphorylation-dependent binding sites surrounding S233 and S259. 14-3-3 proteins can bind two target sequences located on one polypeptide chain simultaneously, thereby increasing binding affinity compared to single-site binding and possibly allowing regulated 14-3-3 binding through gatekeeper phosphorylation. To date, it was unclear whether 14-3-3 proteins can bind the two N-terminal phosphorylation-dependent binding sites of C-RAF simultaneously. Fluorescence polarization using phosphorylated peptides demonstrated that S233 is the low-affinity and S259 is the high-affinity binding site, while simultaneous engagement of both sites by 14-3-3ζ enhances affinity compared to single-site binding. Determination of a 1:1 stoichiometry for the di-phosphorylated peptide binding to one 14-3-3ζ dimer with isothermal titration calorimetry was supported by the crystal structure of the 14-3-3ζ/C-RAFpS233,pS259 complex. Cellular localization studies validate the significance of these sites for cytoplasmic retention of C-RAF, suggesting an extended mechanism of RAF regulation by 14-3-3 proteins. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Biological, chemical and other data collected aboard the THOMAS G. THOMPSON during cruise TN259 in the North Pacific Ocean from 2010-11-23 to 2010-12-22 (NODC Accession 0117399)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC accession 0117399 includes biological, chemical, optical and physical data collected aboard the THOMAS G. THOMPSON during cruise TN259 in the North Pacific...

  11. Microbispora sp. LGMB259 Endophytic Actinomycete Isolated from Vochysia divergens (Pantanal, Brazil) Producing β-Carbolines and Indoles with Biological Activity

    Science.gov (United States)

    Savi, Daiani C.; Shaaban, Khaled A.; Vargas, Nathalia; Ponomareva, Larissa V.; Possiede, Yvelise M.; Thorson, Jon S.; Glienke, Chirlei; Rohr, Jürgen

    2014-01-01

    Endophytic actinomycetes encompass bacterial groups that are well known for the production of a diverse range of secondary metabolites. Vochysia divergens is a medicinal plant, common in the “Pantanal” region (Brazil) and was focus of many investigations, but never regarding its community of endophytic symbionts. During a screening program, an endophytic strain isolated from the V. divergens, was investigated for its potential to show biological activity. The strain was characterized as Microbispora sp. LGMB259 by spore morphology and molecular analyze using nucleotide sequence of the 16S rRNA gene. Strain LGMB259 was cultivated in R5A medium producing metabolites with significant antibacterial activity. The strain produced 4 chemically related β-carbolines, and 3 Indoles. Compound 1-Vinyl-β-carboline-3-carboxylic acid displayed potent activity against the Gram-positive bacterial strains Micrococcus luteus NRRL B-2618 and Kocuria rosea B-1106, and was highly active against two human cancer cell lines, namely the prostate cancer cell line PC3 and the non-small-cell lung carcinoma cell line A549, with IC50 values of 9.45 and 24.67 µM, respectively. 1-Vinyl-β-carboline-3-carboxylic acid also showed moderate activity against the yeast Saccharomyces cerevisiae ATCC204508, as well as the phytopathogenic fungiPhyllosticta citricarpa LGMB06 and Colletotrichum gloeosporioides FDC83. PMID:25385358

  12. Microbispora sp. LGMB259 endophytic actinomycete isolated from Vochysia divergens (Pantanal, Brazil) producing β-carbolines and indoles with biological activity.

    Science.gov (United States)

    Savi, Daiani C; Shaaban, Khaled A; Vargas, Nathalia; Ponomareva, Larissa V; Possiede, Yvelise M; Thorson, Jon S; Glienke, Chirlei; Rohr, Jürgen

    2015-03-01

    Endophytic actinomycetes encompass bacterial groups that are well known for the production of a diverse range of secondary metabolites. Vochysia divergens is a medicinal plant, common in the "Pantanal" region (Brazil) and was focus of many investigations, but never regarding its community of endophytic symbionts. During a screening program, an endophytic strain isolated from the V. divergens, was investigated for its potential to show biological activity. The strain was characterized as Microbispora sp. LGMB259 by spore morphology and molecular analyze using nucleotide sequence of the 16S rRNA gene. Strain LGMB259 was cultivated in R5A medium producing metabolites with significant antibacterial activity. The strain produced 4 chemically related β-carbolines, and 3 Indoles. Compound 1-vinyl-β-carboline-3-carboxylic acid displayed potent activity against the Gram-positive bacterial strains Micrococcus luteus NRRL B-2618 and Kocuria rosea B-1106, and was highly active against two human cancer cell lines, namely the prostate cancer cell line PC3 and the non-small-cell lung carcinoma cell line A549, with IC50 values of 9.45 and 24.67 µM, respectively. 1-Vinyl-β-carboline-3-carboxylic acid also showed moderate activity against the yeast Saccharomyces cerevisiae ATCC204508, as well as the phytopathogenic fungi Phyllosticta citricarpa LGMB06 and Colletotrichum gloeosporioides FDC83.

  13. ONKALO pose experiment. Geophysical logging and imaging of drillholes ONK-PP223, ONK-PP226, ONK-PP254 and ONK-PP259...261

    Energy Technology Data Exchange (ETDEWEB)

    Tarvainen, A.-M. (Suomen Malmi Oy, Espoo (Finland))

    2011-08-15

    Suomen Malmi Oy conducted geophysical drillhole logging as well as optical and acoustic imaging of shallow drillholes ONK-PP223, ONK-PP226, ONK-PP254, ONKPP259, ONK-PP260 and ONK-PP261 at ONKALO in the investigation niche ONKTKU- 3 (POSE) between December 2009 and June 2010. The survey is a part of Posiva Oy's detailed investigation program for the final disposal of spent nuclear fuel. The assignment included the field work and data processing. The report describes field operation, equipment as well as processing procedures and shows the obtained results and an analysis of their quality in the appendices. The raw and processed data are delivered digitally in WellCAD, PDF and Excel format. (orig.)

  14. First Parallax Measurements Towards a 6.7 GHz Methanol Maser with the Australian Long Baseline Array - Distance to G339.884-1.259

    CERN Document Server

    Krishnan, V; Reid, M J; Brunthaler, A; Sanna, A; McCallum, J; Reynolds, C; Bignall, H E; Phillips, C J; Dodson, R; Rioja, M; Caswell, J L; Chen, X; Dawson, J R; Fujisawa, K; Goedhart, S; Green, J A; Hachisuka, K; Honma, M; Menten, K; Shen, Z Q; Voronkov, M A; Walsh, A J; Xu, Y; Zhang, B; Zheng, X W

    2015-01-01

    We have conducted the first parallax and proper motion measurements of 6.7 GHz methanol maser emission using the Australian Long Baseline Array (LBA). The parallax of G339.884$-$1.259 measured from five epochs of observations is 0.48$\\pm $0.08 mas, corresponding to a distance of $2.1^{+0.4}_{-0.3}$ kpc, placing it in the Scutum spiral arm. This is consistent (within the combined uncertainty) with the kinematic distance estimate for this source at 2.5$\\pm $0.5 kpc using the latest Solar and Galactic rotation parameters. We find from the Lyman continuum photon flux that the embedded core of the young star is of spectral type B1, demonstrating that luminous 6.7 GHz methanol masers can be associated with high-mass stars towards the lower end of the mass range.

  15. 259 - 263_Umaru_Mastitis

    African Journals Online (AJOL)

    pc

    t of which 56.7% (55/97) were S. aureus and 12.3% (12/97) w hylococci (CONS). The high prevalence of both clinical and subclin e isolation of S. aureus and CONS are of great public health concern ..... of crottin goat cheese made in different.

  16. Eruption of the Continental Flood Basalts at ~259 Ma in the Emeishan Large Igneous Province, SW China: Evidence from Laser Microprobe 40Ar/39Ar Dating

    Institute of Scientific and Technical Information of China (English)

    HOU Zengqian; CHEN Wen; LU Jiren

    2006-01-01

    A suite of continental flood basalts sampled over a vast exposure and stratigraphic thickness in the Emeishan large igneous province (LLP), SW China was investigated for laser microprobe 40Ar/39Ar dating. There are two 40Ar/39Ar age groups for these basalts, corresponding to 259-246 Ma and 177-137 Ma, respectively. A well-defined isochron gives an eruption age of huge quantities of mafic magmas at 258.9±3.4 Ma, which is identical to previous dating and paleontological data. Much younger 40Ar/39Ar ages for some basalts with low-greenschist metamorphic facies probably recorded a late thermo-tectonic event caused by collision between the Yangtze and Qiangtang continental blocks during the Mesozoic, which resulted in the reset of argon isotope system. The 40Ar/39Ar age data, we present here, combined with previous dating and paleontological data, suggest relatively short duration (about 3 Ma) of mafic volcanism, which have important implication on mantle plume genesis of the Emeishan continental flood basalts in the LIP.

  17. Phosphorylation of the norepinephrine transporter at threonine 258 and serine 259 is linked to protein kinase C-mediated transporter internalization

    DEFF Research Database (Denmark)

    Jayanthi, Lankupalle D; Annamalai, Balasubramaniam; Samuvel, Devadoss J

    2006-01-01

    ester (beta-PMA)-induced phosphorylation of NET occurs on serine and threonine residues. Beta-PMA treatment inhibited NE transport, reduced plasma membrane hNET levels, and stimulated hNET phosphorylation in human placental trophoblast cells expressing the WT-hNET. Substance P-mediated activation...... of the G alpha(q)-coupled human neurokinin 1 (hNK-1) receptor coexpressed with the WT-hNET produced effects similar to beta-PMA via PKC stimulation. In striking contrast, an hNET double mutant harboring T258A and S259A failed to show NE uptake inhibition and plasma membrane redistribution by beta-PMA or SP....... Most interestingly, the plasma membrane insertion of the WT-hNET and hNET double mutant were not affected by beta-PMA. Although the WT-hNET showed increased endocytosis and redistribution from caveolin-rich plasma membrane domains following beta-PMA treatment, the hNET double mutant was completely...

  18. Jacobo-Velázquez, D.A and Cisneros-Zevallos, L. An Alternative Use of Horticultural Crops: Stressed Plants as Biofactories of Bioactive Phenolic Compounds. Agriculture 2012, 2, 259-271

    Directory of Open Access Journals (Sweden)

    Luis Cisneros-Zevallos

    2013-09-01

    Full Text Available The authors are sorry to report that some data in the text (Section 2, Section 2.1.1. and Section 2.1.2 and Table 1 were incorrect in reference [1], doi: 10.3390/agriculture2030259, website: http://www.mdpi.com/2077-0472/2/3/259. Our mistake was basically in the calculations of changes observed in the reported values in those references; unfortunately we did not detect the errors at the time of publication. However, since we saw them afterwards, we believed it was pertinent to make the corrections. The authors would, therefore, like to make the following corrections to the paper:

  19. PHOTOSYNTHETIC ACTIVE RADIATION (PAR) profile data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN262 and others as part of the GB project from 1995-01-12 to 1995-06-04 (NODC Accession 0106520)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0106520 includes profile and physical data collected aboard the ENDEAVOR during cruises EN259, EN262, EN264, EN266 and EN267I in the North Atlantic...

  20. CHLOROPHYLL A and PHAEOPIGMENTS profile data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN262 and others as part of the GB project from 1995-01-11 to 1995-06-16 (NODC Accession 0104395)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0104395 includes profile and biological data collected aboard the ENDEAVOR during cruises EN259, EN262, EN264, EN266 and EN267II in the North Atlantic...

  1. CONDUCTIVITY, WIND DIRECTION, SHORTWAVE IRRADIANCE, AIR TEMPERATURE and other underway - surface data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN260 and others as part of the GB project from 1995-01-10 to 1995-07-14 (NODC Accession 0104428)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0104428 includes underway - surface, meteorological, physical, chemical and optical data collected aboard the ENDEAVOR during cruises EN259, EN260,...

  2. CONDUCTIVITY, WIND DIRECTION, SHORTWAVE IRRADIANCE, AIR TEMPERATURE and other underway - surface data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN260 and others as part of the GB project from 1995-01-10 to 1995-07-14 (NODC Accession 0105305)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0105305 includes underway - surface, meteorological, chemical, physical and optical data collected aboard the ENDEAVOR during cruises EN259, EN260,...

  3. CONDUCTIVITY, WIND DIRECTION, SHORTWAVE IRRADIANCE, AIR TEMPERATURE and other underway - surface data collected in the North Atlantic Ocean on the ENDEAVOR cruises EN259, EN260 and others as part of the GB project from 1995-01-10 to 1995-07-14 (NODC Accession 0106342)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC Accession 0106342 includes underway - surface, meteorological, chemical, physical and optical data collected aboard the ENDEAVOR during cruises EN259, EN260,...

  4. 39 CFR 259.1 - Government.

    Science.gov (United States)

    2010-07-01

    ... as State governments. In establishing such fees and charges, the Postal Service considers the value of time of the personnel directly involved in the performance of the service, including direct...

  5. June2007 EAST AFRICAN MEDICAL JOURNAL 259

    African Journals Online (AJOL)

    2007-06-01

    Jun 1, 2007 ... 84 No. 6 Iune 2007. REFRACTIVE ERRORS IN TYPE 2 DIABETIC PATIENTS ... course of diabetic retinopathy, there were 88 eyes. E ' t' ' d' (N .= 190 ) ... diabetic medical clinic and had no prior knowledge of the study, hence ...

  6. 7 CFR 917.259 - Delinquent assessments.

    Science.gov (United States)

    2010-01-01

    ... balance and late payment charge for the number of days all or any part of the assessment specified in the... a late payment charge on any assessment that has not been received in the Peach Commodity Committee... on the handler's assessment statement. The late payment charge shall be 10 percent of the unpaid...

  7. 30 CFR 259.002 - Definitions.

    Science.gov (United States)

    2010-07-01

    ..., or develop, or produce (or to do any or all of these) oil and gas, coal, oil shale, tar sands, and...). Oil means a mixture of hydrocarbons that exists in a liquid or gaseous phase in an underground...

  8. Reference: 259 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available velopment in Arabidopsis. 1 163-73 16113228 2005 Sep Plant physiology Braybrook Siobhan A|Fischer Robert L|Fujioka Shozo|Goldberg Rob...ert B|Harada John J|Nagata Noriko|Pelletier Julie|Yamagishi Kazutoshi|Yee Kelly Matsudaira|Yoshida Shigeo

  9. The Analysis of the Basic features of Peasant Households with Different Income levels——A Case of 259 Peasant Households in Three Villages of Hebei Province,China

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    According to the urban and rural income levels and the national poverty line,peasant households are classified into poor households,middle-income households and wealthy households.Based on the investigation data of 259 peasant households in three villages of Hebei Province,the features of family structure,economy,ideology and communication of peasant households with different income levels in current status are analyzed.The result shows that there are great differences in family structure,ideology,economy and communication of peasant households with different income levels.The low-income households are featured by unreasonable family structure,heavy burden,conservative behavior and blocking information.While the middle and high income households are good at communicating and willing to take risk and armed with high skills.Based on this,relevant suggestions are put forward to promote the development of peasant households,such as optimizing family structure,cultivating the capacity of the core numbers of the family,guiding households to choose a suitable development path,encouraging farmers to work out,ensuring the legitimate rights and interests of migrant workers,flourishing rural culture,and setting up good platform for the communication of households.

  10. Atypical juvenile presentation of GM2 gangliosidosis AB in a patient compound-heterozygote for c.259G>T and c.164C>T mutations in the GM2A gene

    Directory of Open Access Journals (Sweden)

    Carla Martins

    2017-06-01

    Full Text Available GM2-gangliosidosis, AB variant is an extremely rare autosomal recessive inherited disorder caused by mutations in the GM2A gene that encodes GM2 ganglioside activator protein (GM2AP. GM2AP is necessary for solubilisation of GM2 ganglioside in endolysosomes and its presentation to β-hexosaminidase A. Conversely GM2AP deficiency impairs lysosomal catabolism of GM2 ganglioside, leading to its storage in cells and tissues. We describe a 9-year-old child with an unusual juvenile clinical onset of GM2-gangliosidosis AB. At the age of 3 years he presented with global developmental delay, progressive epilepsy, intellectual disability, axial hypertonia, spasticity, seizures and ataxia, but without the macular cherry-red spots typical for GM2 gangliosidosis. Brain MRI detected a rapid onset of diffuse atrophy, whereas whole exome sequencing showed that the patient is a compound heterozygote for two mutations in GM2A: a novel nonsense mutation, c.259G>T (p.E87X and a missense mutation c.164C>T (p.P55L that was recently identified in homozygosity in patients of a Saudi family with a progressive chorea-dementia syndrome. Western blot analysis showed an absence of GM2AP in cultured fibroblasts from the patient, suggesting that both mutations interfere with the synthesis and/or folding of the protein. Finally, impaired catabolism of GM2 ganglioside in the patient's fibroblasts was demonstrated by metabolic labeling with fluorescently labeled GM1 ganglioside and by immunohistochemistry with anti-GM2 and anti-GM3 antibodies. Our observation expands the molecular and clinical spectrum of molecular defects linked to GM2-gangliosidosis and suggests novel diagnostic approach by whole exome sequencing and perhaps ganglioside analysis in cultured patient's cells.

  11. 259名本专科护生职业成熟度特点及比较研究%Features of Vocational Maturity of College Nursing Students and Nursing Undergraduates

    Institute of Scientific and Technical Information of China (English)

    石海霞; 陈瑜

    2015-01-01

    目的:比较某医科大学本专科护生职业成熟度差异,为针对性地对护生进行就业指导和职业生涯规划提供依据。方法采用便利抽样的方法,使用职业成熟度量表对某医科大学259名本专科护生进行调查。结果本专科护生职业成熟度总均分为(2.54±0.18)分。本科护生职业成熟度得分为(2.55±0.18)分,专科护生职业成熟度得分为(2.54±0.17)分,不同年级及学历本专科护生职业成熟度总均分差异无统计学意义(P>0.05)。其中,专科护生职业选择的主动性显著高于本科护生(F=6.87,P0.05),大一专科护生职业选择的主动性高于大一本科护生(t=2.70,P0.05). Initiative of career choice of college nursing students was significantly higher than that of nursing undergraduates ( F=6.87,P0.05). Initiative of career choice of college nursing freshmen was significantly higher than that of undergraduate nursing freshmen ( t=2.70,P<0.05) and undergraduate nursing sophomores presented more professional self knowledge than nursing college sophomores ( t=3.44,P<0.05). Junior nursing undergraduates were more confident than junior college nursing students (t= 2.28,P< 0.05). The score of flexibility of junior nursing college students was higher than that of senior students (F=3.46,P<0.05) and the score of professional knowledge and professional self knowledge of students from different grades indicated statistical significance (F=3.99, 3.14; all P<0.05). Conclusion Career maturity of nursing students maintains in a medium and above level. Differences exist in professional knowledge, professional self knowledge, flexibility, utilitarian and initiative and we should pay attention to strengthening professional self knowledge, and flexibility of career choice of senior students and initiative of nursing undergraduates.

  12. Dicty_cDB: SLA259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 3 0.0 1 BD092935 |BD092935.1 Methods and compositions for synthesis of long chain... polyunsaturated fatty acids in plants. 1471 0.0 1 BD082645 |BD082645.1 Methods and compositions for synthes...is of long chain polyunsaturated fatty acids. 1471 0.0 1 BD082630 |BD082630.1 Methods and compositions for s

  13. 30 CFR 206.259 - Determination of washing allowances.

    Science.gov (United States)

    2010-07-01

    ... either a straight-line depreciation method based on the life of equipment or on the life of the reserves... as a separate line entry on the Form MMS-4430. (2) In conducting reviews and audits, MMS will examine... reporting it as a separate line entry on the Form MMS-4430. When necessary or appropriate, MMS may direct...

  14. 40 CFR 180.259 - Propargite; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ... byproducts 0.1 Lemon 5.0 Milk, fat (0.08 ppm in milk) 2.0 Nectarine 4.0 Orange 10.0 Peanut 0.1 Peppermint, tops 50.0 Poultry, fat 0.1 Potato 0.1 Sheep, fat 0.1 Sheep, meat 0.1 Sheep, meat byproducts 0.1...

  15. 14 CFR 171.259 - Performance requirements: General.

    Science.gov (United States)

    2010-01-01

    .../240 volt, 60 Hz, 3-wire single phase AC power source. (c) ISMLS ground equipment must meet the following service conditions: (1) AC line parameters, DC voltage, elevation, and duty: 120 V nominal value... V (±0.2 V).* AC line frequency (60 Hz), 57 Hz to 63 Hz (±0.2 Hz).* DC voltage (48 V), 44 V to 52...

  16. Dicty_cDB: SSI259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available F824319 |BF824319.1 NcEST3a21h12.y1 Nc 1314 Tachyzoite cDNA Neospora caninum cDNA...ST3a40b01.y1 Nc 1314 Tachyzoite cDNA Neospora caninum cDNA 5' similar to TR:Q9ZNS3 Q9ZNS3 RIBOSOMAL PROTEIN ...S27. ;, mRNA sequence. 36 0.10 2 BF249095 |BF249095.1 NcEST3a07a05.y1 Nc 1314 Tachyzoite cDNA Neospora

  17. Dicty_cDB: SLE259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 999. 1.19 Translated Amino Acid sequence ilhlkldekn*kfk*gyrkgkn*rlm**wqdqknvedvsvtd*k*yvtfnv*lti*v*tg krwimrvylqqitahggkskp*e*higs...dqknvedvsvtd*k*yvtfnv*lti*v*tg krwimrvylqqitahggkskp*e*higsradkk*wst*kgylrrreicdraifrrkastk epkkgvntfsekrk*k

  18. Dicty_cDB: SFH259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available QITNSIFKNNNAI--- ---NKFISNTALKSGGGLYTLAVADITSGILGSFII*fk*sn*w*wii***fgksil*cn iyfk*snrewwwiifirf*niyatiklsik...k--- ---NKFISNTALKSGGGLYTLAVADITSGILGSFII*fk*sn*w*wii***fgksil*cn iyfk*snrewwwiif

  19. Dicty_cDB: SSB259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SYNTHASE SUBUNIT AC39 ;, mRNA sequence. 76 3e-14 2 AI067312 |AI067312.1 EST208990 Schistosoma mansoni, Phil LoVerde/Joe...se vacuolar, 40 kDa subunit, mRNA sequence. 54 2e-04 2 AI067329 |AI067329.1 EST209007 Schistosoma mansoni, Phil LoVerde/Joe...unit, mRNA sequence. 54 3e-04 2 AI067953 |AI067953.1 EST209642 Schistosoma mansoni, Phil LoVerde/Joe... subunit, mRNA sequence. 54 3e-04 2 AI067936 |AI067936.1 EST209624 Schistosoma mansoni, Phil LoVerde/Joe Mer

  20. 1935 15' Quad #259 Aerial Photo Mosaic Index

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — Aerial Photo Reference Mosaics contain aerial photographs that are retrievable on a frame by frame basis. The inventory contains imagery from various sources that...

  1. Dicty_cDB: CHE259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available f75f12.y1 Gm-c1078 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1078-2184 ... sa37e09.y1 Gm-c1004 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1004-1505 5' similar to TR:O24653 O...HIBITOR. ;, mRNA sequence. 62 8e-06 1 BE800797 |BE800797.1 sq98c12.y1 Gm-c1049 Glycine max cDNA clone GENOME SYSTEMS.... 62 8e-06 1 AW397479 |AW397479.1 sg79d05.y1 Gm-c1007 Glycine max cDNA clone GENOME SYSTEMS...ce. 62 8e-06 1 BG790353 |BG790353.1 sae68c10.y1 Gm-c1064 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-

  2. Dicty_cDB: AFK259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available |AW306469.1 se51b09.y1 Gm-c1017 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1017-2418 5', mRNA seque...nce. 34 8e-04 3 BF008963 |BF008963.1 ss71e08.y1 Gm-c1062 Glycine max cDNA clone GENOME SYSTEMS... 0.001 3 AI899992 |AI899992.1 sb97c10.y1 Gm-c1012 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1012-6...ine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1017-3950 5', mRNA sequence. 34 0.002 3 AQ501049 |AQ501049.1

  3. 4 CFR 25.9 - Soliciting, vending, and debt collection.

    Science.gov (United States)

    2010-01-01

    ... the “Manual on Fund Raising Within the Federal Service,” issued by the U.S. Office of Personnel... Reform Act of 1978 (Pub. L. 95-454) or the General Accounting Office Personnel Act of 1980, Public Law 96-191 (31 U.S.C. sec. 732(e)); (d) Occupants of space leased for commercial purposes, or made...

  4. Dicty_cDB: VSJ259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available Frame B: fsrrcrshrin*krschqhhsin*flslplkermaky*dfirqnlygsitpcllrillvs ntpilg**eclilsfltlltfcfpsigs*kinl**kn...tlf*ykkk--- ---fsrrcrshrin*krschqhhsin*flslplkermaky*dfirqnlygsitpcllril lvsntpilg**eclilsfltlltfcfpsmeakklt

  5. Dicty_cDB: SFA259 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 1 Translated Amino Acid sequence llaywififsktp*qiiik*KMAKVGEGDPRWIVENREDGHNVNGWHWSEKDCLPWSKNT IGGLFDKKVIQET...TGIPIDEFEKTEEGWKRNILDRIKHTFXXXX Frame B: llaywififsktp*qiiik*KMAKVGEGDPRWIVENREDGHNVNGWHWSEKDCLPWSKNT IGGLFD

  6. Etiology of bacterial meningitis among children aged 2-59 months in Salvador, Northeast Brazil, before and after routine use of Haemophilus influenzae type b vaccine Etiologia da meningite bacteriana em crianças com idade entre 2 e 59 meses em Salvador, Nordeste do Brasil, antes e depois do uso rotineiro da vacina para Haemophilus influenzae tipo b

    Directory of Open Access Journals (Sweden)

    Cristiana M. Nascimento-Carvalho

    2004-06-01

    Full Text Available OBJECTIVE: To describe the frequency of etiologic agents of bacterial meningitis (BM among children aged 2-59 months in a sample of patients in Salvador, Northeast Brazil, with emphasis on the frequency of BM of unknown etiology (BMUE, just before, during and after the implementation of routine immunization of infants with Haemophilus influenzae type b (Hib vaccination. METHOD: Demographic, clinical and cerebrospinal fluid (CSF information was collected from the chart of every patient, aged 2-59 months, whose CSF exam was performed at the CSF Lab - José Silveira Foundation, between January 1989 and December 2001. Every CSF exam was completely performed according to standard methods. The etiologic diagnosis was based on either culture and/or latex-agglutination test. When the agent was only seen on Gram stained smear, the diagnosis was descriptive. BMUE was defined as: glucose 100 mg / dl, white blood cell count > 20 cells / mm³, percentage of neutrophils > 80%. RESULTS: Of 1519 patients, 894 (58.9% had normal exams and BM was diagnosed in 95 (6.2%. Etiologic agents were: Hib (44.2%, meningococcus (13.7%, Gram-negative bacilli (11.6%, Mycobacterium tuberculosis (6.3%, pneumococcus (4.2%, other agents (4.2%; BMUE was diagnosed in 15.8% of cases with BM. By analysing the frequency of BMUE and Hib among all exams performed yearly, the peaks were recorded in 1989 (5.3% and 1990 (16.9%, respectively, decreasing to 0.7% and 0% in 2001. CONCLUSION: It is possible that the implementation of the conjugate Hib vaccine during the 1990's has been decreasing not only the occurrence of Hib meningitis but also of BMUE.OBJETIVO: Descrever a freqüência dos agentes etiológicos de meningite bacteriana (MB em amostra das crianças com idade entre 2 e 59 meses, em Salvador, Nordeste do Brasil, com ênfase na freqüência de MB de etiologia indeterminada (MBEI, antes, durante e após a implementação da imunização rotineira de lactentes com vacina para

  7. 乌鲁木齐市5 259名少数民族大学生艾滋病相关性行为及吸毒行为调查分析%Study of sexual behavior and drug abuse behavior among minority students of university related to AIDS in Urumqi

    Institute of Scientific and Technical Information of China (English)

    李迎

    2010-01-01

    Objective To investigate sexual behavior and drug abuse behavior systematically among university minority students to provide evidence and reference for universities and relevant government bodies; to work out strategy for STD/HIV prevention. Methods A total of 5 259 minority undergraduates of comprehensive universities were investigated in Urumqi; an anonymous questionnaire was used to collect information about AIDS related practice from minority undergraduates random selected in a grade among four universities. Results 9.30% of minority undergraduates in their sex, 18.00% sexually active undergraduates used condom during their sex. 21.41% of male undergraduates with sexual experience had ever used condoms which was better than 8.96% of female undergraduates. Moreover, 1.65 % of mi nority undergraduates had a history of drug abuse in universities, 1.08% of minority undergraduates of universities had ever used intravenous drugs. Conclusions Sexually active undergraduates of universities have used condom less during their sex. The awareness of preventing STD/AIDS among university students is quite low, their self - protection awareness and condom using rate are low too. So systematic and scientific sex education and STD/AIDS health education and behavior intervention are pressing and urgent.%目的 了解少数民族大学生的性行为及吸毒行为状况,为学校和有关部门制订性病、艾滋病健康教育和行为干预措施提供参考依据.方法 采用多级分层整群抽样法对乌鲁木齐市4所综合性大学的5259名少数民族大学生采用统一凋查问卷进行调查.结果 9.30%的少数民族大学生发生过性行为,在发生过性行为的少数民族大学生中,仅有18.00%的学生采取了保护性措施,男大学生安全套的使用率(21.41%)高于女大学生(8.96%);另一方面,1.65%的少数民族大学生有吸毒史,1.08%的学生近6个月注射过毒品.结论 发生性行为的少数民族学生中较少采取保

  8. Chemical Identification of Dubnium as a Decay Product of Element 115 Produced in the Reaction $\\rm {^{48}Ca}+{^{243}Am}$

    CERN Document Server

    Dmitriev, S N; Utyonkov, V K; Shishkin, S V; Eremin, A V; Lobanov, Yu V; Chepigin, V I; Sokol, E A; Tsyganov, Yu S; Vostokin, G K; Aksenov, N V; Hussonnois, M; Itkis, M G; Aggeler, H W; Schumann, D; Bruchertseifer, H; Eichler, R; Shaughnessy, D A; Wilk, P A; Kenneally, J M; Stoyer, M A; Wild, J F

    2004-01-01

    The results of an experiment designed to identify $^{268}$Db as the terminal isotope in the $\\alpha $-decay chain of element 115 produced via the ${\\rm {^{243}Am}}({\\rm {^{48}Ca}},3n){\\rm {^{288}115}}$ reaction are presented. The $^{243}$Am target was bombarded with a beam dose of $3.4\\cdot 10^{18}$ $^{48}$Ca projectiles at an energy of 247 MeV at the center of the target. The reaction products were collected in the surface layer of a copper catcher block, which was removed with a lathe and then dissolved in concentrated HNO$_{3}$. The group-5 elements were separated by sorption onto Dowex $50{\\times} 8$ cation-exchange resin with subsequent desorption using 1 M HF, which forms anionic fluoride complexes of group-5 elements. The eluent was evaporated onto a 0.4 $\\mu$m thick polyethylene foil that was placed between a pair of semiconductor detectors surrounded by $^{3}$He neutron counters for measurement of $\\alpha$ particles, fission fragments, and neutrons. In the course of the experiment, we observed 15 spo...

  9. diarrhoea among 2-59 months children treated in Black Lion

    African Journals Online (AJOL)

    Diarrhoea is acommonly associated problem in children with Zinc deficiency and also leads to excess zinc - losses. ..... improved in the appetite scale, their care takers were also ... sanitation practice, identifying the cause of acute diarrhea.

  10. Yeast Interacting Proteins Database: YGL181W, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available rexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of ...gene name YAP6 Prey description Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithiu

  11. Yeast Interacting Proteins Database: YLR423C, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available cine zipper (bZIP) transcription factor; overexpression increases sodium and lithium...cription factor; overexpression increases sodium and lithium tolerance; computational analysis suggests a ro

  12. Yeast Interacting Proteins Database: YLR447C, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available or; overexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulat...erexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation of

  13. Yeast Interacting Proteins Database: YDR311W, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available rexpression increases sodium and lithium tolerance; computational analysis sugges... zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance; computational an

  14. Yeast Interacting Proteins Database: YGR066C, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ession increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expre...verexpression increases sodium and lithium tolerance; computational analysis suggests a role in regulation o

  15. Yeast Interacting Proteins Database: YDR259C, YLR423C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ion increases sodium and lithium tolerance; computational analysis suggests a role in regulation of expressi...tative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium toleran

  16. Prognostic factorsin inoperable adenocarcinoma of the lung: A multivariate regression analysis of 259 patiens

    DEFF Research Database (Denmark)

    Sørensen, Jens Benn; Badsberg, Jens Henrik; Olsen, Jens

    1989-01-01

    and degree of differentiation, the new international staging system for lung cancer, and seven laboratory parameters. Staging of the patients included bone marrow examination but were otherwise nonextensive without routine bone, liver, and brain scans. Factors predicting poor survival were low performance...... status, stage IV disease, no prior nonradical resection, liver metastases, high values of white blood cell count, and lactate dehydrogenase, and low values of aspartate aminotransaminase. The nonradical resection may not be a prognostic factor because of the resection itself but may rather serve...... in the former Cox model to be of importance (performance status, stage, surgical resection, WBC, aspartate aminotransaminase, and lactate dehydrogenase). This simplified model appears to be a feasible clinical tool, allowing for prognostic stratification of patients when first the inoperability of the patient...

  17. 14 CFR 259.4 - Contingency plan for lengthy tarmac delays.

    Science.gov (United States)

    2010-01-01

    ... considerations preclude such service; (4) For all flights, assurance of operable lavatory facilities, as well as... aircraft did not return to the gate by the 3-hour mark). (e) Unfair and Deceptive Practice. An air carrier... Plan for Lengthy Tarmac Delays will be considered an unfair and deceptive practice within the...

  18. SU-E-J-259: Quantification of Rotational Localization Offset in Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Y; Nguyen, N; Lee, S; Liu, F [Rhode Island Hospital / Warren Alpert Medical, Providence, RI (United States)

    2014-06-01

    Purpose: To verify the necessity of 6D localization detection and correction in radiation therapy. Methods: An anthropomorphic head and neck phantom was used to test the BrainLab ExacTrac x-ray imaging system. After initial positioning, both ExacTrac and the on-board kV CBCT were used to detect the offset at the same position, using both manual and automatic registration algorithms. Then 6D offset including rotational errors up to 5 degree were introduced. Both ExacTrac and CBCT were used to correct the offsets and the residual errors were evaluated. Finally, 6D offset detected by ExacTrac for a C-Spine patient was reported. Results: The differences in 3D offset detected by ExacTrac and CBCT were 1.5 ± 1.2(Lateral), 2.7 ± 2.7(Vertical), and 4.0 ± 6.3(longitudinal) mm with manual registration while the corresponding differences decreased to 0.6 ± 0.3, 1.0 ± 0.3, and 0.3 ± 0.3 when automatic registration were used. CBCT corrected the translational offset to within 0.5 mm but the rotational errors remained and detected by the ExacTrac system (Yaw=2.1, Roll=1.1, Pitch=1.4 degree). When similar offset was introduced and corrected using ExacTrac, the residual error detected by both CBCT and ExacTrac were within 0.5 mm / 0.5 degree. The average offset from the 112 ExacTrac x-ray corrections for the C-Spine patient was 0.6 ± 1.6 (lateral), 5.4 ± 8(vertical), 1.6±1.1(longitudinal) mm, and 0.7 ± 0.6 (pitch), 0.7 ± 0.4(roll), 1.2 ± 0.7 (yaw) degree. Larger rotational errors, with a maximum of 2.7 degree (corresponds to about 1.5 to 4.5 mm offset for a POI 10 to 30 cm away from the isocenter), were observed when couch rotational were involved. Conclusion: Rotational errors are common in patient localization, especially when couch rotation is involved. Both appropriate imaging system and 6D robotic couch are necessary to detect and correct the rotational localization errors.

  19. The Lyman-alpha Reference Sample: I. Survey outline and first results for Markarian 259

    CERN Document Server

    Östlin, Göran; Duval, Florent; Sandberg, Andreas; Rivera-Thorsen, Thoger; Marquart, Thomas; Orlitova, Ivana; Adamo, Angela; Melinder, Jens; Guaita, Lucia; Atek, Hakim; Cannon, John M; Gruyters, Pieter; Herenz, Edmund Christian; Kunth, Daniel; Laursen, Peter; Mas-Hesse, J Miguel; Micheva, Genoveva; Pardy, Hector Oti-Floranes Stephen A; Roth, Martin M; Schaerer, Daniel; Verhamme, Anne

    2014-01-01

    The Lyman-alpha reference sample (LARS) is a program with the Hubble Space Telescope (HST) that provides a sample of local universe laboratory galaxies in which to study the astrophysics of the visibility and strength of the Lyman-alpha (Lya) line of hydrogen. This article presents an overview of the survey, its selection function and HST imaging observations. The sample was selected from the GALEX+SDSS catalogue at z=0.028-0.19, in order to allow Lya to be captured with combinations of long pass filters in the Solar Blind Channel (SBC) of HST/ACS. In addition, LARS utilises Halpha and Hbeta narrow, and U, B, i broad-band imaging with ACS and WFC3. In order to study galaxies in which large numbers of Lya photons are produced we demanded an Halpha equivalent width > 100{\\AA}. The sample of 14 galaxies covers far UV (FUV) luminosities that overlaps with those of high-z Lya emitters and Lyman Break Galaxies (LBGs). We present the reduction steps used to obtain the Lya images, including our LARS eXtraction softwa...

  20. 259 “Team Pair Solo” Cooperative Learning and Personality Type ...

    African Journals Online (AJOL)

    User

    learning strategy and students' personality type on achievement and attitude to Chemistry. 175 SS2 .... business and political groups (Jung, 1971). Introversion is the focus on the ..... WETA's Educational website, or WETA, Washington D.C..

  1. Obesity, bariatric surgery and nutritional implications - doi:10.5020/18061230.2007.p259

    Directory of Open Access Journals (Sweden)

    Michele Novaes Ravelli

    2012-01-01

    Full Text Available Obesity is an important nutritional deviation that is exponentially increasing in Brazil and in the world, becoming a public health problem. The World Health Organization verified in 2005 that 1.6 billion people above 15 years old were overweight and 400 million were obese. Among children, 20 million were overweight. Amongst the different treatments for the obesity the bariatric surgery has been used very often nowadays, for being effective against weight excess and associated co-morbidities, both for the adult and youngster populations. The surgical techniques are divided in restrictive, disabsorptive and mixed procedures. Each technique promotes digestive and absorptive distinct alterations, needing, therefore, an exclusive multidisciplinary educational program, directed both to pre and postsurgery periods, emphasizing the habits of physical activity and the necessity to adhere to the restricted dietary recommendations. The surgeries promote a severe reduction in the consumption, which induces to the ingestion of diets that are hypocaloric and deficient in micronutrients, with consequent nutritional complications.

  2. Yeast Interacting Proteins Database: YBR270C, YDR259C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p, homolo... actin cytoskeletal dynamics during polarized growth and cell wall integrity; interacts with Slm1p and Slm2p

  3. SU-E-T-259: Particle Swarm Optimization in Radial Dose Function Fitting for a Novel Iodine-125 Seed

    Energy Technology Data Exchange (ETDEWEB)

    Wu, X [University of Alabama at Birmingham, Birmingham, Al (United States); Duan, J; Popple, R; Huang, M; Shen, S; Brezovich, I [University of Alabama Birmingham, Birmingham, AL (United States); Cardan, R [UAB University of Alabama, Birmingham, Birmingham, AL (United States); Benhabib, S [University of Alabama at Birmingham, Birmingham, AL (United States)

    2014-06-01

    Purpose: To determine the coefficients of bi- and tri-exponential functions for the best fit of radial dose functions of the new iodine brachytherapy source: Iodine-125 Seed AgX-100. Methods: The particle swarm optimization (PSO) method was used to search for the coefficients of the biand tri-exponential functions that yield the best fit to data published for a few selected radial distances from the source. The coefficients were encoded into particles, and these particles move through the search space by following their local and global best-known positions. In each generation, particles were evaluated through their fitness function and their positions were changed through their velocities. This procedure was repeated until the convergence criterion was met or the maximum generation was reached. All best particles were found in less than 1,500 generations. Results: For the I-125 seed AgX-100 considered as a point source, the maximum deviation from the published data is less than 2.9% for bi-exponential fitting function and 0.2% for tri-exponential fitting function. For its line source, the maximum deviation is less than 1.1% for bi-exponential fitting function and 0.08% for tri-exponential fitting function. Conclusion: PSO is a powerful method in searching coefficients for bi-exponential and tri-exponential fitting functions. The bi- and tri-exponential models of Iodine-125 seed AgX-100 point and line sources obtained with PSO optimization provide accurate analytical forms of the radial dose function. The tri-exponential fitting function is more accurate than the bi-exponential function.

  4. Formative Assessment and Elementary School Student Academic Achievement: A Review of the Evidence. REL 2017-259

    Science.gov (United States)

    Klute, Mary; Apthorp, Helen; Harlacher, Jason; Reale, Marianne

    2017-01-01

    Formative assessment is a process that engages teachers and students in gathering, interpreting, and using evidence about what and how students are learning in order to facilitate further student learning during a short period of time. The process offers the potential to guide educator decisions about midstream adjustments to instruction that…

  5. Speech therapy in peripheral facial palsy: an orofacial myofunctional approach - doi:10.5020/18061230.2009.p259

    Directory of Open Access Journals (Sweden)

    Hipólito Virgílio Magalhães Jr

    2012-01-01

    Full Text Available Objective: To delineate the contributions of speech therapy in the rehabilitation of peripheral facial palsy, describing the role of orofacial myofunctional approach in this process. Methods: A literature review of published articles since 1995, held from March to December 2008, based on the characterization of peripheral facial palsy and its relation with speechlanguage disorders related to orofacial disorders in mobility, speech and chewing, among others. The review prioritized scientific journal articles and specific chapters from the studied period. As inclusion criteria, the literature should contain data on peripheral facial palsy, quotes on the changes in the stomatognathic system and on orofacial miofunctional approach. We excluded studies that addressed central paralysis, congenital palsy and those of non idiopathic causes. Results: The literature has addressed the contribution of speech therapy in the rehabilitation of facial symmetry, with improvement in the retention of liquids and soft foods during chewing and swallowing. The orofacial myofunctional approach contextualized the role of speech therapy in the improvement of the coordination of speech articulation and in the gain of oral control during chewing and swallowing Conclusion: Speech therapy in peripheral facial palsy contributed and was outlined by applying the orofacial myofunctional approach in the reestablishment of facial symmetry, from the work directed to the functions of the stomatognathic system, including oralfacial exercises and training of chewing in association with the training of the joint. There is a need for a greater number of publications in this specific area for speech therapy professional.

  6. 美国调香师对若干食用香料的评价(259

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    (2533)环己甲酸乙酯 Ethyl Cyclohexane Carboxylate来源——PentaManufacturingCo.;FEMA#3544,CAS#3289.28—9;天然来源——咖啡;香气特征——@100%:果香,酵香,葡萄酒香和甜香;尝味特征——@lppm:甜的,糖果样的,果味和浆果样,

  7. 47 CFR 25.259 - Time sharing between NOAA meteorological satellite systems and non-voice, non-geostationary...

    Science.gov (United States)

    2010-10-01

    ... Atmospheric Administration (“NOAA”) satellite systems. When calculating the protection areas for a NOAA... contact person and telephone number so that claims of harmful interference into NOAA earth station users... Administration (“NTIA”) notifies the Commission that NOAA is receiving unacceptable interference from a...

  8. Changing picture of acute kidney injury in pregnancy: Study of 259 cases over a period of 33 years.

    Science.gov (United States)

    Prakash, J; Pant, P; Prakash, S; Sivasankar, M; Vohra, R; Doley, P K; Pandey, L K; Singh, U

    2016-01-01

    The incidence of acute kidney injury (AKI) in pregnancy is declining in developing countries but still remains a major cause of maternal and fetal morbidity and mortality. The aim of the study was to analyze the changing trends in pregnancy related AKI (PR-AKI) over a period of thirty-three years. Clinical characteristics of PR-AKI with respect to incidence, etiology and fetal and maternal outcomes were compared in three study periods, namely 1982-1991,1992-2002 and 2003-2014. The incidence of PR-AKI decreased to 10.4% in 1992-2002, from 15.2% in 1982-1991, with declining trend continuing in 2003-2014 (4.68%).Postabortal AKI decreased to 1.49% in 2003-2014 from 9.4% in 1982-1991of total AKI cases. The AKI related to puerperal sepsis increased to 1.56% of all AKI cases in 2003-2014 from 1.4% in 1982-1991. Preeclampsia/eclampsia associated AKI decreased from 3.5% of total AKI cases in 1982-1991 to 0.54% in 2003-2014. Pregnancy associated - thrombotic microangiopathy and acute fatty liver of pregnancy were uncommon causes of AKI. Hyperemesis gravidarum associated AKI was not observed in our study. Incidence of renal cortical necrosis (RCN) decreased to 1.4% in 2003-2014 from 17% in 1982-1991.Maternal mortality reduced to 5.79% from initial high value 20% in 1982-1991. The progression of PR-AKI to ESRD decreased to1.4% in 2003-2014 from 6.15% in 1982-1991. The incidence of PR-AKI has decreased over last three decades, mainly due to decrease in incidence of postabortal AKI. Puerperal sepsis and obstetric hemorrhage were the major causes of PR-AKI followed by preeclampsia in late pregnancy. Maternal mortality and incidence and severity of RCN have significantly decreased in PR-AKI. The progression to CKD and ESRD has decreased in women with AKI in pregnancy in recent decade. However, the perinatal mortality did not change throughout study period.

  9. Acute Uncomplicated Febrile Illness in Children Aged 2-59 months in Zanzibar – Aetiologies, Antibiotic Treatment and Outcome

    Science.gov (United States)

    Elfving, Kristina; Shakely, Deler; Andersson, Maria; Baltzell, Kimberly; Ali, Abdullah S.; Bachelard, Marc; Falk, Kerstin I.; Ljung, Annika; Msellem, Mwinyi I.; Omar, Rahila S.; Parola, Philippe; Xu, Weiping; Petzold, Max; Trollfors, Birger; Björkman, Anders; Lindh, Magnus; Mårtensson, Andreas

    2016-01-01

    Background Despite the fact that a large proportion of children with fever in Africa present at primary health care facilities, few studies have been designed to specifically study the causes of uncomplicated childhood febrile illness at this level of care, especially in areas like Zanzibar that has recently undergone a dramatic change from high to low malaria transmission. Methods We prospectively studied the aetiology of febrile illness in 677 children aged 2–59 months with acute uncomplicated fever managed by IMCI (Integrated Management of Childhood Illness) guidelines in Zanzibar, using point-of-care tests, urine culture, blood-PCR, chest X-ray (CXR) of IMCI-pneumonia classified patients, and multiple quantitative (q)PCR investigations of nasopharyngeal (NPH) (all patients) and rectal (GE) swabs (diarrhoea patients). For comparison, we also performed NPH and GE qPCR analyses in 167 healthy community controls. Final fever diagnoses were retrospectively established based on all clinical and laboratory data. Clinical outcome was assessed during a 14-day follow-up. The utility of IMCI for identifying infections presumed to require antibiotics was evaluated. Findings NPH-qPCR and GE-qPCR detected ≥1 pathogen in 657/672 (98%) and 153/164 (93%) of patients and 158/166 (95%) and 144/165 (87%) of controls, respectively. Overall, 57% (387/677) had IMCI-pneumonia, but only 12% (42/342) had CXR-confirmed pneumonia. Two patients were positive for Plasmodium falciparum. Respiratory syncytial virus (24.5%), influenza A/B (22.3%), rhinovirus (10.5%) and group-A streptococci (6.4%), CXR-confirmed pneumonia (6.2%), Shigella (4.3%) were the most common viral and bacterial fever diagnoses, respectively. Blood-PCR conducted in a sub-group of patients (n = 83) without defined fever diagnosis was negative for rickettsiae, chikungunya, dengue, Rift Valley fever and West Nile viruses. Antibiotics were prescribed to 500 (74%) patients, but only 152 (22%) had an infection retrospectively considered to require antibiotics. Clinical outcome was generally good. However, two children died. Only 68 (11%) patients remained febrile on day 3 and three of them had verified fever on day 14. An additional 29 (4.5%) children had fever relapse on day 14. Regression analysis determined C-reactive Protein (CRP) as the only independent variable significantly associated with CXR-confirmed pneumonia. Conclusions This is the first study on uncomplicated febrile illness in African children that both applied a comprehensive laboratory panel and a healthy control group. A majority of patients had viral respiratory tract infection. Pathogens were frequently detected by qPCR also in asymptomatic children, demonstrating the importance of incorporating controls in fever aetiology studies. The precision of IMCI for identifying infections requiring antibiotics was low. PMID:26821179

  10. Opposing effects of cAMP and T259 phosphorylation on plasma membrane diffusion of the water channel aquaporin-5 in Madin-Darby canine kidney cells

    DEFF Research Database (Denmark)

    Koffman, Jennifer Skaarup; Christensen, Eva Arnspang; Marlar, Saw

    2015-01-01

    Aquaporin-5 (AQP5) facilitates passive water transport in glandular epithelia in response to secretory stimuli via intracellular pathways involving calcium release, cAMP and protein kinase A (PKA). In epithelial plasma membranes, AQP5 may be acutely regulated to facilitate water transport in resp...

  11. Ground state capture in $^{14}$N(p,$\\gamma$)$^{15}$O studied above the 259 keV resonance at LUNA

    CERN Document Server

    Trautvetter, H P; Bonetti, R; Broggini, C; Caciolli, A; Confortola, F; Corvisiero, P; Costantini, H; Elekes, Z; Formicola, A; Fülöp, Z; Gervino, G; Guglielmetti, A; Gyurky, Gy; Gustavino, C; Imbriani, G; Junker, M; Lemut, A; Limata, B; Marta, M; Mazzocchi, C; Menegazzo, R; Prati, P; Roca, V; Rolfs, C; Alvarez, C Rossi; Somorjai, E; Straniero, O; Strieder, F; Terrasi, F; Vezzu, S; Vomiero, A

    2007-01-01

    We report on a new measurement of $^{14}$N(p,$\\gamma$)$^{15}$O for the ground state capture transition at $E_p$ = 360, 380 and 400 keV, using the 400 kV LUNA accelerator. The true coincidence summing effect --the major source of error in the ground state capture determination-- has been significantly reduced by using a Clover--type gamma detector.

  12. 47 CFR 90.259 - Assignment and use of frequencies in the bands 216-220 MHz and 1427-1432 MHz.

    Science.gov (United States)

    2010-10-01

    ... COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PRIVATE LAND MOBILE RADIO SERVICES Standards for... applicants that establish eligibility in the Industrial/Business Pool. (2) All operation is secondary to the fixed and mobile services, including the Low Power Radio Service. (3) In the 216-217 MHz band, no...

  13. Reseña. James Torres, Minería y moneda en el Nuevo Reino de Granada (Bogotá: Instituto Colombiano de Antropología e Historia, 2013. Pp. 259. ISBN 978-958-8181-99-8

    Directory of Open Access Journals (Sweden)

    Óscar Granados

    2014-12-01

    Full Text Available Este libro es un estudio innovador de la minería y su vinculación con la estructura monetaria y el desempeño económico durante la segunda mitad del siglo XVIII. La obra busca agrupar las tres variables como parte de una renovación historiográfica, y para esto analiza al sector minero desde la perspectiva de los precios relativos, haciendo un profundo trabajo de archivo que fortalece la argumentación para resolver sus hipótesis. Torres vincula a la región con mayor producción de oro de la Nueva Granada, comparándola con otras regiones mineras como el Alto Perú y la Nueva España.

  14. Science and Technology of Nanostructured Magnetic Materials: Proceedings of a NATO Advanced Study Institute Conference Held in Aghia Pelaghia, Crete, Greece on 24 June -6 July 1990. NATO ASI Series B: Physics. Volume 259

    Science.gov (United States)

    1990-07-06

    this important advantage ,wer the Fresnel and Focault methods must be set the disadvantage that, in order to obtain an unobstructed reference wave, only... Focault methods - its linearity. It can be shown 19 that the ideal DPC detector is a first moment detector whose response is proportional to spatial... Focault and DPC images for an assumed variation of induction across a pair of 1800 domain walls, illustrating the linearity of DPC. Note the similarity

  15. Multibeam collection for TN259: Multibeam data collected aboard Thomas G. Thompson from 2010-11-23 to 2010-12-22, departing from Seattle, WA and returning to Honolulu, HI

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  16. Discovery of 5-Chloro-1-(5-chloro-2-(methylsulfonyl)benzyl)-2-imino-1,2-dihydropyridine-3-carboxamide (TAK-259) as a Novel, Selective, and Orally Active α1D Adrenoceptor Antagonist with Antiurinary Frequency Effects: Reducing Human Ether-a-go-go-Related Gene (hERG) Liabilities.

    Science.gov (United States)

    Sakauchi, Nobuki; Kohara, Yasuhisa; Sato, Ayumu; Suzaki, Tomohiko; Imai, Yumi; Okabe, Yuichi; Imai, Shigemitsu; Saikawa, Reiko; Nagabukuro, Hiroshi; Kuno, Haruhiko; Fujita, Hisashi; Kamo, Izumi; Yoshida, Masato

    2016-04-14

    A novel structural class of iminopyridine derivative 1 was identified as a potent and selective human α1D adrenoceptor (α1D adrenergic receptor; α1D-AR) antagonist against α1A- and α1B-AR through screening of an in-house compound library. From initial structure-activity relationship studies, we found lead compound 9m with hERG K(+) channel liability. To develop analogues with reduced hERG K(+) channel inhibition, a combination of site-directed mutagenesis and docking studies was employed. Further optimization led to the discovery of (R)-9s and 9u, which showed antagonistic activity by a bladder strip test in rats with bladder outlet obstruction, as well as ameliorated cystitis-induced urinary frequency in rats. Ultimately, 9u was selected as a clinical candidate. This is the first study to show the utility of iminopyridine derivatives as selective α1D-AR antagonists and evaluate their effects in vivo.

  17. Quaderni di filologia e lingue romanze 7 (1992, Supplemento Terza serie, Attidel Convegno "Relazione di viaggi fra Italia e Spagna" Macerata, Università degli Studi, 15-17 dicembre 1992, 259 pp.; 8(1993, 273 pp.; 9(1994, 285 pp.; 10(1995, 346 pp.

    Directory of Open Access Journals (Sweden)

    Pavao Tekavčić

    1996-12-01

    Full Text Available Il periodico maceratese, nato nel 1979, continua ad apparire a ritmo annuale re­ golare. Avendo recensito i voll. 1985-1992 nel numero 34 di «Linguistica», presen­ tiamo qui le annate citate nel titolo, concentrandoci sempre sui contributi di interesse linguistico (o almeno filologico, che continuano ad essere in minoranza di fronte a quelli di argomento letterario.

  18. Chemical studies of elements with Z ≥ 104 in liquid phase

    Energy Technology Data Exchange (ETDEWEB)

    Nagame, Yuichiro, E-mail: nagame.yuichiro@jaea.go.jp [Advanced Science Research Center, Japan Atomic Energy Agency (JAEA), Tokai, Ibaraki 319-1195 (Japan); Kratz, Jens Volker [Institut für Kernchemie, Johannes Gutenberg-Universität Mainz, Fritz-Straßmann-Weg 2, 55128 Mainz (Germany); Schädel, Matthias [Advanced Science Research Center, Japan Atomic Energy Agency (JAEA), Tokai, Ibaraki 319-1195 (Japan)

    2015-12-15

    Recent studies of the chemical separation and characterization experiments of the first three transactinide elements, rutherfordium (Rf), dubnium (Db), and seaborgium (Sg), conducted atom-at-a-time in liquid phases, are reviewed. A short description on experimental techniques based on partition methods, specifically automated rapid chemical separation systems, is also given. A newly developed experimental approach to investigate single atoms of the heaviest elements with an electrochemical method is introduced. Perspectives for liquid-phase chemistry experiments on heavier elements are briefly discussed.

  19. Moçambique e seu “diminuto número de habitantes”: recenseamentos da população da África oriental portuguesa, no último quartel do século XVIII - doi: 10.4025/dialogos.v11i1e2.59 Moçambique and its “decreasing inhabitants”: population censuses in portuguese east Africa in the second half of the 18th century - doi: 10.4025/dialogos.v11i1e2.59 Mozambique y su “diminuto número de habitantes”: los censos de población de los dominios portugueses en África oriental durante el último cuarto del siglo XVIII

    Directory of Open Access Journals (Sweden)

    Ana Paula Wagner

    2010-05-01

    Full Text Available Este texto tem por objetivo discutir uma política da coroa portuguesa que pretendia, na sua base, um melhor conhecimento das populações que habitavam seus domínios. A partir de ações político-administrativas iniciadas na década de 1770, foram realizados recenseamentos periódicos em diferentes localidades do Império Português. Discutimos, particularmente, a documentação produzida pelos administradores da região da África Oriental portuguesa. Ao privilegiar a situação da capitania de Moçambique e Rios de Senna, no último quartel do século XVIII, analisamos as estruturas demográficas e categorias sociais daquela região, e discutimos a importância da população no interior da política portuguesa da época.Current research on population censuses in Portuguese East Africa in the second half of the 18th Century discusses the policies of the Portuguese Crown. Portugal wanted to know better the populations living under its dominion. As from political and administrative activities in the 1770s, periodical censuses were undertaken in different parts of the Portuguese Empire. Documents produced by the administrators of Portuguese East Africa are investigated. Highlighting the situation of Mozambique and Rios de Senna, the demographic structures and social categories of that region and the importance of hinterland population within Portuguese policies of the period are discussed.Este texto tiene por objetivo discutir la política de la Corona portuguesa que pretendía conocer mejor las poblaciones que habitaban en sus territorios. A partir de acciones político-administrativas iniciadas durante la década de 1770, se realizaron varios censos en diferentes localidades del Imperio Portugués en forma periódica. En particular, aquí discutimos la documentación emanada de los administradores de la región portuguesa de África Oriental. Al privilegiar la situación de la Capitanía de Mozambique y Ríos de Senna durante el último cuarto del siglo XVIII, analizamos las estructuras demográficas y las categorías sociales de esta región, a la vez que discutimos la importancia de la población en el marco de la política portuguesa de aquella época

  20. 17 CFR 200.800 - OMB control numbers assigned pursuant to the Paperwork Reduction Act.

    Science.gov (United States)

    2010-04-01

    ... Commission that are rules and regulations and codified in 17 CFR either in full text or incorporated by... collection requirement 17 CFR part or section where identified and described Current OMB control No... Form U5A 259.5a 3235-0170 Form U5B 259.5b 3235-0170 Form U5S 259.5s 3235-0164 Form U-1 259.101...

  1. High-Temperature Ferromagnetism in Cr- and Mn-Implanted Al(sub x)Ga(sub 1-x)N

    Science.gov (United States)

    2007-09-23

    Uspenskii , E. Kulatov, H. Mariette, H. Nakayama, H. Ohta, J. Magnetism and Magnetic Mat. 258-259, 248 (2003). [4] T. Dietl, Semicon. Science and Tech...287 (2000) 1019–1022. [3] Y. Uspenskii , E. Kulatov, H. Mariette, H. Nakayama, H. Ohta, J. Magn. Magn. Mater. 258–259 (2003) 248–250. [4] T. Dietl

  2. Drug: D08420 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08420 Drug Primaquine (INN); Kanaprim (TN) C15H21N3O 259.1685 259.3467 D08420.gif Antiprotozoa...oquinolines P01BA03 Primaquine D08420 Primaquine (INN) USP drug classification [BR:br08302] Antiparasitics Antiprotozoa

  3. Gclust Server: 201699 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 201699 OSA_@259 Cluster Sequences - 111 no annotation 1 1.00e-50 14.29 0.0 0.0 0.0 0.0 0.0 Show 2016...99 Cluster ID 201699 Sequence ID OSA_@259 Link to cluster sequences Cluster Sequences Link

  4. GETDB: 112880 [GETDB

    Lifescience Database Archive (English)

    Full Text Available fb sg, cns internal semi lethal - comment1:A, comment2:59A1-A4 - - - - Show 11288... Also known as - Original Comments comment1:A, comment2:59A1-A4 Disc (Image) - Disc (number) 0 Embryo (Image

  5. NCBI nr-aa BLAST: CBRC-SCER-05-0001 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available CBRC-SCER-05-0001 ref|XP_001642400.1| hypothetical protein Kpol_259p5 [Vanderwaltoz...yma polyspora DSM 70294] gb|EDO14542.1| hypothetical protein Kpol_259p5 [Vanderwaltozyma polyspora DSM 70294] XP_001642400.1 0.0 78% ...

  6. Drug: D01591 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01591 Drug Ethyl 4-nitrophenyl ethylphosphonate (JAN); p-Nitrophenyl-o-ethyl ethyl...phosphonate C10H14NO5P 259.061 259.1956 D01591.gif Same as: C13048 CAS: 546-71-4 PubChem: 7848654 LigandBox: D01591

  7. Frequency and type of toenail tumors in the dromedary camel

    Directory of Open Access Journals (Sweden)

    M.I. Siddiqui

    2013-06-01

    Full Text Available A total of 275 dromedary camels (16 males and 259 females of local “Arabiyat” breed suffering from different types and degrees of severity of toenail tumors were surgically treated. Histopathological examination of the tissue samples removed from 50 tumor-like growths (2 males and 48 females revealed three types of tumors; squamous cell carcinoma (70%, spiny keratoderma (22% and fibroma (8%. An increased incidence of tumors was recorded in the medial when compared to the lateral toenails in both sexes. In females, the incidence in the medial toenails was 90/259 (34.75% and 71/259 (27.41% in the right and left forelimbs respectively when compared to the lateral toenails which was 25/259 (9.65% and 5/259 (1.93% for the respective right and left forelimbs. In the hind limbs, this ratio was 29/259 (11.20% and 20/259 (7.72% for right and left medial toenails respectively, whereas it was 17/259 (6.56% and 2/259 (0.77% for the right and left lateral toenails respectively. Similar to the observations in female camels, male camels also showed a higher incidence of these tumors in the medial when compared to the lateral toenails in both fore and hind limbs. Based on these findings, we conclude that in the dromedary camels, the medial toenails of the fore limbs are most commonly affected with tumors; with the most common tumor being the squamous cell carcinoma.

  8. Chemistry of the superheavy elements.

    Science.gov (United States)

    Schädel, Matthias

    2015-03-13

    The quest for superheavy elements (SHEs) is driven by the desire to find and explore one of the extreme limits of existence of matter. These elements exist solely due to their nuclear shell stabilization. All 15 presently 'known' SHEs (11 are officially 'discovered' and named) up to element 118 are short-lived and are man-made atom-at-a-time in heavy ion induced nuclear reactions. They are identical to the transactinide elements located in the seventh period of the periodic table beginning with rutherfordium (element 104), dubnium (element 105) and seaborgium (element 106) in groups 4, 5 and 6, respectively. Their chemical properties are often surprising and unexpected from simple extrapolations. After hassium (element 108), chemistry has now reached copernicium (element 112) and flerovium (element 114). For the later ones, the focus is on questions of their metallic or possibly noble gas-like character originating from interplay of most pronounced relativistic effects and electron-shell effects. SHEs provide unique opportunities to get insights into the influence of strong relativistic effects on the atomic electrons and to probe 'relativistically' influenced chemical properties and the architecture of the periodic table at its farthest reach. In addition, they establish a test bench to challenge the validity and predictive power of modern fully relativistic quantum chemical models.

  9. Browse Title Index

    African Journals Online (AJOL)

    Items 51 - 100 of 259 ... Vol 13, No 1 (2007), Changing the course of schizophrenia - predictors of treatment ... Cognitive functioning and associated factors in older adults in .... provision of mental health services and development of psychiatry in ...

  10. 75 FR 62061 - Proposed Flood Elevation Determinations

    Science.gov (United States)

    2010-10-07

    ..., these elevations, once finalized, will be used by insurance agents and others to calculate appropriate... Cecil County. Egypt Road. Approximately 977 feet +259 +260 downstream of Elbow Road. Dogwood Run At...

  11. Atomic physics: A strange kind of liquid

    Science.gov (United States)

    Laburthe-Tolra, Bruno

    2016-11-01

    Interactions between the magnetic dipoles of dysprosium atoms in an ultracold gas can produce a 'self-bound' droplet. This provides a useful isolated system for probing the quantum-mechanical properties of ultracold gases. See Letter p.259

  12. Drug: D02259 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 259.gif Antineoplastic; Diagnostic aid [thyroid function determination]; Radioactive agent [DS:H00032] Thera... affecting cellular function 43 Radioactive drugs 430 Radioactive drugs 4300 Radio

  13. InterProScan Result: FS813871 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS813871 FS813871_1_ORF2 0ACBAF36E259F207 SUPERFAMILY SSF103473 MFS general substra...te transporter 8e-29 T IPR016196 Major facilitator superfamily, general substrate transporter ...

  14. QTL Information Table: 369 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qET-6 Physiological trait Eating quality Endosperm translucency RFLP C)Interval BIL...tative trait loci underlying appearance quality of rice grains (Oryza sativa L.). Yi Chuan Xue Bao 30, 251-259. ...

  15. QTL Information Table: 368 [Q-TARO

    Lifescience Database Archive (English)

    Full Text Available qPGWC-6b Physiological trait Eating quality Percentages of grains with chalkiness R...3). Mapping quantitative trait loci underlying appearance quality of rice grains (Oryza sativa L.). Yi Chuan Xue Bao 30, 251-259. ...

  16. Alzheimer's Disease Facts and Figures

    Medline Plus

    Full Text Available ... expected to be $56 billion. Health care costs increase with the presence of dementia. People with Alzheimer's ... with Alzheimer's or other dementias are projected to increase from $259 billion in 2017 to more than $ ...

  17. A Good Image Model Eases Restoration

    Science.gov (United States)

    2002-02-06

    algorithms, and various classical as well as unexpected new applications of the BV ( bounded variation ) image model, first introduced into image processing by Rudin, Osher, and Fatemi in 1992 Physica D, 60:259-268.

  18. Human Estimation of Slope, Distance, and Height of Terrain in Simulated Lunar Conditions

    Science.gov (United States)

    2009-02-01

    9643 APPENDIX J DEVON ISLAND DISTANCE REFERENCE 259 Distance References NBA Basketball Court Width 15 meters 50 feet...Cockpit Hours: Simulator Airframe: Hours: Sports Baseball Years: Beginner Intermediate Advanced Basketball Years: Beginner

  19. EHR Incentive Programs - Data and Reports

    Data.gov (United States)

    U.S. Department of Health & Human Services — As of March 2013, more than 259,000 health care providers received payment for participating in the Medicare and Medicaid Electronic Health Record (EHR) Incentive...

  20. Drug: D04711 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04711 Drug Cernitin pollen extract (JAN); Cernilton; Cernilton (TN) Therapeutic ca...genital and anal organ agents 259 Miscellaneous 2590 Miscellaneous D04711 Cernitin pollen extract (JAN) CAS: 8054-43-1 PubChem: 17398147 ...

  1. Eesti raamatu isa Richard Antik / Hannes Oja

    Index Scriptorium Estoniae

    Oja, Hannes

    2002-01-01

    rets. rmt.: Raamatu valgusel: Richard Antik 100: [raamatukogutegelane ja bibliograaf : 1901-1998] : artikleid ja bibliograafia / Eesti Kirjandusmuuseum; [koostanud Merike Kiipus ja Piret Noorhani; toimetanud Tiina Saluvere]. Tartu, 2001. 259 lk.

  2. Sources Informing Undergraduate College Student Perceptions of Psychologists

    National Research Council Canada - National Science Library

    McDonald, Dana N; Wantz, Richard A; Firmin, Michael W

    2014-01-01

    ... psychologists from other HSPs.We surveyed 259 students enrolled in a general psychology class at a selective private comprehensive university in the Midwest in order to determine the sources that inform their perceptions...

  3. control of the cassava mealybug in africa: lessons from a

    African Journals Online (AJOL)

    All rights reserved O1994, African Crop Science Society. CONTROL OF THE ...... American Chemical Society, Washington, D. C. ... Bulletin of Entomological Society of. America 30:18-26 ... Proceedings Tall Timbers Conference 2:59-. 81. Hahn ...

  4. Elementõ polititsheskoi mifologii Tjuttsheva (kommentari k state 1844 g.) / Aleksandr Ospovat

    Index Scriptorium Estoniae

    Ospovat, Aleksandr

    1999-01-01

    Bibl. lk. 259-263. Kokkuvõte inglise k. lk. 321. Kiri ajalehe "Allgemeine Zeitung" (Augsburg) toimetajale Gustav Kolbile (1844, prantsuse k.). Artikli venek. versioon (pealk. "Venemaa ja Saksamaa") publitseeriti ajakirjas Russki arhiv (1873, nr. 10)

  5. Research Article

    African Journals Online (AJOL)

    2016-06-17

    Jun 17, 2016 ... Department of Physics, North Tehran Branch, Islamic Azad University, Tehran, Iran. Published online: 17 June ... INTRODUCTION. Magnetic .... receiver for nuclear magnetic resonance microscopy, Science, 1993, 259, 5-793.

  6. 'Transatlantic Print Culture, 1880-1940: Emerging Media, Emerging Modernisms', edited by Ann Ardis and Patrick Collier

    Directory of Open Access Journals (Sweden)

    Janet Floyd

    2009-11-01

    Full Text Available A review of 'Transatlantic Print Culture, 1880-1940: Emerging Media, Emerging Modernisms', edited by Ann Ardis and Patrick Collier (London: Palgrave Macmillan, 2008. Hardback, 259 pages, £50, ISBN 9780554269.

  7. Disease: H01134 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ) is familial cases of highly malignant, aggressive, embryonal neoplasms manifested in early infancy and child...yndrome--familial cancer syndromes in children. Radiology 259:298-302 (2011) PMID

  8. South African Journal for Research in Sport, Physical Education and ...

    African Journals Online (AJOL)

    Equine-assisted therapy as intervention for motor proficiency in children with autism spectrum ... Effects of exercise training on performance and function in individuals with cerebral palsy: A critical ... Estelle D. Watson, Yoga Coopoo, 259 - 267 ...

  9. Developing advanced units of learning using IMS Learning Design level B

    NARCIS (Netherlands)

    Koper, Rob; Burgos, Daniel

    2005-01-01

    Please cite the original publication: Koper, R., Burgos, D. (2005). Developing advanced units of learning using IMS Learning Design level B. International Journal on Advanced Technology for Learning, 2 (4), 252-259.

  10. EST Table: FS773374 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS773374 E_FL_fcaL_01E22_R_0 10/09/28 46 %/259 aa ref|XP_975194.1| PREDICTED: similar to something about.../265 aa gnl|Amel|GB19080-PA 10/09/10 46 %/259 aa gi|91081571|ref|XP_975194.1| PREDICTED: similar to something about silencing protein 10 [Tribolium castaneum] FS823506 fcaL ...

  11. Design of Novel Organic Thin Film Transistors for Wearable Electronics

    Science.gov (United States)

    2012-08-01

    Materials Engineering as of 2011 on the project of “Modelling of Phthalocyanine based thin film organic transistors”. Experimental data on output...Brunel University Wolfson Centre for Materials Processing Michael Sterling, 259 Uxbridge, United Kingdom UB8 3PH EOARD Grant 10-3056...NAME(S) AND ADDRESS(ES) Brunel University Wolfson Centre for Materials Processing Michael Sterling, 259 Uxbridge, United Kingdom UB8 3PH 8

  12. Drug: D03036 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D03036 Drug Azetepa (USAN/INN) C8H14N5OPS 259.0657 259.2684 D03036.gif Antineoplast...ic CAS: 125-45-1 PubChem: 17397191 LigandBox: D03036 NIKKAJI: J5.373B ATOM 16 1 P1a P 24.7722 -18.0161 2 N1y

  13. Domain Modeling: NP_009127.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_009127.1 chr19 Eukaryotic proteases d1brbe_ chr19/NP_009127.1/NP_009127.1_apo_33...-259.pdb d1co7e_ chr19/NP_009127.1/NP_009127.1_holo_33-259.pdb blast 85D,86H,87S,88L,89Q,90N,91K,92D,95E 73H,120D,210G,211D,212S _CA 1 ...

  14. Influence of Rolling Treatment on Interfacial Shear Strength of Steel-mushy Al-7graphite Bonding Plate

    Institute of Scientific and Technical Information of China (English)

    Peng ZHANG; Yunhui DU; Hanwu LIU; Daben ZENG; Jianzhong CUI; Limin BA

    2004-01-01

    At room temperature, the rolling treatment of steel-mushy Al-7graphite bonding plate was carried out under different relative reduction. The influence of rolling on interfacial mechanical property of this bonding plate was studied. The results show that, for steel-mushy Al-7graphite bonding plate which is made up of 1.2 mm in thickness 08Al steel plate and 2.0 mm in thickness Al-7graphite layer, there is a nonlinear relationship between interfacial shear strength of bonding plate and relative reduction of rolling. When relative reduction of rolling is smaller than 2.59%, with the increasing of relative reduction, interfacial shear strength of bonding plate increases gradually. When relative reduction of rolling is bigger than 2.59%, with the increasing of relative reduction, interfacial shear strength of bonding plate decreases continuously. When relative reduction of rolling is 2.59%, the largest interfacial shear strength 77.0 MPa can be obtained.

  15. Salvage radiation therapy following radical prostatectomy. A national Danish study

    DEFF Research Database (Denmark)

    Ervandian, Maria; Høyer, Morten; Petersen, Stine Elleberg

    2015-01-01

    BACKGROUND: The purpose of this observational cohort study was to evaluate the outcome and prognostic factors following salvage radiotherapy (SRT) in a consecutive national cohort. MATERIAL AND METHODS: Between 2006 and 2010, 259 patients received SRT in Denmark. Patient- and cancer-related chara......BACKGROUND: The purpose of this observational cohort study was to evaluate the outcome and prognostic factors following salvage radiotherapy (SRT) in a consecutive national cohort. MATERIAL AND METHODS: Between 2006 and 2010, 259 patients received SRT in Denmark. Patient- and cancer...

  16. Drug: D00925 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ibacterials J01XX01 Fosfomycin D00925 Fosfomycin tromethamine (USAN) USP drug classification [BR:br08302] Antibacterials Antibacteria...N) Antiinfectives [BR:br08307] Antibacterials Cell wall biosynthesis inhibitor Others UDP-N-acetylglucosamin...bacterial ATC code: J01XX01 UDP-N-acetylglucosamine 1-carboxyvinyltransferase inhib...D00925 Drug Fosfomycin tromethamine (USAN); Monurol (TN) C3H7O4P. C4H11NO3 259.0821 259.1941 D00925.gif Anti

  17. Inhibition of Raf/MAPK signaling in Xenopus oocyte extracts by Raf-1-specific peptides.

    Science.gov (United States)

    Radziwill, G; Steinhusen, U; Aitken, A; Moelling, K

    1996-10-01

    Raf-1 is an upstream element of the mitogen-activated protein kinase (MAPK) pathway which leads to cell proliferation and differentiation. In this study Raf-1 derived peptides comprising the conserved amino acid residues Arg89 and Ser259, involved in binding of activated Ras and 14-3-3 proteins, respectively, were shown to interfere with MAPK activation in extracts from immature Xenopus oocytes. Lipids prepared from oocyte extracts can stimulate MAPK in a Ras- and protein kinase C-independent manner. This lipid-induced MAPK activation is blocked by a Raf-1 derived peptide comprising Ser259.

  18. La inútil añoranza de la normalidad

    Directory of Open Access Journals (Sweden)

    Margarita Valencia

    2012-01-01

    Full Text Available Litchis de Madagascar. Aquiles Cuervo. Editorial Elfin de la noche. Buenos Aires, 2011, 91 págs. El ruido de las cosas al caer. Juan Gabriel Vásquez. Premio Alfaguara de novela 2011. Alfaguara. Bogotá. 2011, 259 págs. Tres ataúdes blancos. Antonio Ungar. Premio Herralde de Novela. Editorial Anagrama. Barcelona. 2010, 259 págs. Suicídame. Andrés Arias. Ediciones B. Bogotá, 2010, 261 págs. C.M. no récord. Juan Álvarez. Alfaguara. Bogotá, 2010, 262 págs.

  19. SCOR: a structural classification of RNA database.

    Energy Technology Data Exchange (ETDEWEB)

    Klosterman, Peter S.; Tamura, Makio; Holbrook, Stephen R.; Brenner, Steven E.

    2001-10-10

    The Structural Classification of RNA (SCOR) database provides a survey of the three-dimensional motifs contained in 259 NMR and X-ray RNA structures. In one classification, the structures are grouped according to function. The RNA motifs, including internal and external loops, are also organized in a hierarchical classification. The 259 database entries contain 223 internal and 203 external loops; 52 entries consist of fully complementary duplexes. A classification of the well-characterized tertiary interactions found in the larger RNA structures is also included along with examples. The SCOR database is accessible at http://scor.lbl.gov.

  20. Drug: D02689 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D02689 Drug Ramelteon (JAN/USAN/INN); Rozerem (TN) C16H21NO2 259.1572 259.3434 D026...sory organs 11 Agents affecting central nervous system 119 Miscellaneous 1190 Miscellaneous D02689 Ramelteon... N NERVOUS SYSTEM N05 PSYCHOLEPTICS N05C HYPNOTICS AND SEDATIVES N05CH Melatonin receptor agonists N05CH02 Ramelteon D02689 Ramelt...eon (JAN/USAN/INN) USP drug classification [BR:br08302] Sleep Disorder Agents Sleep Disorders, Other Ramelt...eon D02689 Ramelteon (JAN/USAN/INN) Target-based classificat

  1. La inútil añoranza de la normalidad

    OpenAIRE

    Margarita Valencia

    2012-01-01

    Litchis de Madagascar. Aquiles Cuervo. Editorial Elfin de la noche. Buenos Aires, 2011, 91 págs. El ruido de las cosas al caer. Juan Gabriel Vásquez. Premio Alfaguara de novela 2011. Alfaguara. Bogotá. 2011, 259 págs. Tres ataúdes blancos. Antonio Ungar. Premio Herralde de Novela. Editorial Anagrama. Barcelona. 2010, 259 págs. Suicídame. Andrés Arias. Ediciones B. Bogotá, 2010, 261 págs. C.M. no récord. Juan Álvarez. Alfaguara. Bogotá, 2010, 262 págs.

  2. International measures project for rational energy use (Survey project of the analysis tool of Asian energy consumption efficiency). List of errata; 1998 nendo kokusai energy shiyo gorika nado taisaku jigyo seigohyo. Asia energy shohi koritsuka bunseki tool chosa jigyo

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    The list of errata was prepared for the data book of the international measures project for rational energy use (Survey project of the analysis tool of Asian energy consumption efficiency). Corrected pages of the data book 1 (1990) are as follows: 187-190, 223-226, 259-262, 295- 298, 369-370, 387-388 and 405-406 on Malaysian data. Corrected pages of the data book 2 (1985) are as follows: 102-105 on Chinese data, 154 on common data, and 187-190, 223-226, 259-262, 295-298, 369-370, 387-388 and 405-406 on Malaysian data. (NEDO)

  3. AcEST: DK952604 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 0. 5' end sequence. DK952604 CL2982Contig1 Show DK952604 Clone id TST38A01NGRL0014_I20 Library TST38 Length ...647 Definition Adiantum capillus-veneris mRNA. clone: TST38A01NGRL0014_I20. 5' end sequence. Accession DK95260... generation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK952604|Adiantum c...ation of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK95260...SYLPGWQKP----YKVVPYEDLH 259 Query: 259 WRFSQRLLDLMWIPMKWLAIPVFALS 336 WR ++ W+PMKWLAI F L+ Sbjct: 260 WRVTRP

  4. SCOR: a Structural Classification of RNA database.

    Science.gov (United States)

    Klosterman, Peter S; Tamura, Makio; Holbrook, Stephen R; Brenner, Steven E

    2002-01-01

    The Structural Classification of RNA (SCOR) database provides a survey of the three-dimensional motifs contained in 259 NMR and X-ray RNA structures. In one classification, the structures are grouped according to function. The RNA motifs, including internal and external loops, are also organized in a hierarchical classification. The 259 database entries contain 223 internal and 203 external loops; 52 entries consist of fully complementary duplexes. A classification of the well-characterized tertiary interactions found in the larger RNA structures is also included along with examples. The SCOR database is accessible at http://scor.lbl.gov.

  5. AcEST: BP916642 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ides f... 35 0.20 sp|Q9NRI5|DISC1_HUMAN Disrupted in schizophrenia 1 protein OS=Ho... 34 0.34 sp|O94386|YGS9...EL----QAHADEVEELRRKMAQ-KISEYEEQLEALLNKCSSLEKQKSR 258 Query: 145 L 143 L Sbjct: 259 L 259 >sp|Q9NRI5|DISC1_HUMAN Disrupted in schizoph...renia 1 protein OS=Homo sapiens GN=DISC1 PE=1 SV=3 Length = 854 Score = 34.3 bits (

  6. Ultra-low gossypol cottonseed: gene-silencing opens up a vast, but underutilized protein resource for human nutrition

    Science.gov (United States)

    Cotton, grown mainly for its fiber, is a major crop in several developing and developed countries across the globe. In 2012, 48.8 million metric tons (MMT) of cottonseed was produced worldwide as a by-product of the 25.9 MMT of cotton lint production (FAO Production Statistics). This amount of cot...

  7. JPRS Report, Science & Technology, Europe & Latin America

    Science.gov (United States)

    1988-04-06

    QUADRO RIASSUNTIVO DEGLI IMPEGNI DEL PIANO SPAZIALE NAZIONALE (mrliardi di lire) Progr. (1) Fasi (2) (3) Totale ( h Fino a! progr. vn/1987...Marco D/L Gestione (27) Struttura Psn/Cnr (28) Supporto ( 29 ) Assistenza tecnica (30 ) Anticipation! (31 ) 1.912.32 172.50 259.50 2.344.33 410.83

  8. Northeast Artificial Intelligence Consortium (NAIC). Volume 7. Automatic Photointerpretation

    Science.gov (United States)

    1990-12-01

    of the shapes to the gray level image was carried out independently. Strategy Vertex Segement % of Correct Attributes Attributes Matches I Position...111 GabrielI. X .and oaR. R., "~Anewstatistical appach to geographic variation trlysis" Syst. Zool., Vol. 18, 1969, pp.259 -270. (121 Kim, S. M

  9. Immunogenicity of a 7-valent pneumococcal conjugate vaccine (PCV7) and impact on carriage in Venezuelan children at risk of invasive pneumococcal diseases

    NARCIS (Netherlands)

    Rivera-Olivero, I.A.; Nogal, B. del; Fuentes, M.; Cortez, R.; Bogaert, D.; Hermans, P.W.M.; Waard, J.H. de

    2014-01-01

    BACKGROUND AND AIMS: We evaluated the immunogenicity of the 7-valent pneumococcal conjugate vaccine (PCV7), and its impact on pneumococcal carriage in Venezuelan children at high risk for invasive pneumococcal disease (IPD). METHODS: 82 children (age 2-59 months) with sickle cell anemia (n=22), chro

  10. 77 FR 59901 - North Pacific Fishery Management Council; Public Meeting

    Science.gov (United States)

    2012-10-01

    ... potential management measures, using the status quo management measures of one fish less than 45 inches or... National Oceanic and Atmospheric Administration RIN 0648-XC259 North Pacific Fishery Management Council... Management Council (Council) Charter Management Implementation Committee will convene via a conference...

  11. Bullying in Students with and without Hearing Loss

    Science.gov (United States)

    Pinquart, Martin; Pfeiffer, Jens P.

    2015-01-01

    While bullying is a common phenomenon at schools in general, very few studies have addressed bullying in students with hearing impairment. This study assessed being bullied and bullying others in 181 adolescents from German schools for students who are deaf and hard of hearing, and in 259 hearing peers from regular schools. Students who are deaf…

  12. Antimicrobial activity of some endemic plant species from Turkey

    African Journals Online (AJOL)

    SERVER

    2007-08-06

    Aug 6, 2007 ... For the determination of antimicrobial activity, 3 g of ground plant parts were ... negative control, 1 ml of methanol – 5 ml of deionized water mixture ..... CAM. 2: 259-263. Dülger B, Ceyhan M, Alitsaous M, Uğurlu E (1999).

  13. Assessing Attitudes of White University Students toward Blacks in a Changing Context.

    Science.gov (United States)

    Minatoya, Lydia Yuriko; Sedlacek, William E.

    1984-01-01

    Measured the attitudes of 259 White college students toward Blacks using a revised version of the Situational Attitude Scale (SAS-14). Results showed students tended to react more negatively to situations where the word "Black" was inserted, compared with situations where race was not indicated. (JAC)

  14. p53 Over-expression and p53 mutations in colon carcinomas: Relation to dietary risk factors

    NARCIS (Netherlands)

    Voskuil, D.W.; Kampman, E.; Kraats, A.A. van; Balder, H.F.; Muijen, G.N.P. van; Goldbohm, R.A.; Veer, P. van 't

    1999-01-01

    Epidemiological studies have suggested that dietary factors may differently affect p53-dependent and p53-independent pathways to colon cancer. Results of such studies may depend on the method used to assess p53 status. This case-control study of 185 colon-cancer cases and 259 controls examines this

  15. Noninvasive assessment of esophageal-gastric varices by spleen stiffness in liver cirrhosis patients

    Institute of Scientific and Technical Information of China (English)

    李庭红

    2012-01-01

    Objective To investigate the value of spleen stiffness measured by transient elastography(FibroScan,FS) for diagnosing esophageal-gastric varices in liver cirrhosis patients. Methods A total of 259 cirrhotic patients in Tianjin Third Central Hospital rom Apr 2011 to Apr 2012,and 30 healthy controls were enrolled

  16. Better theory-of-mind skills in children hearing voices mitigate the risk of secondary delusion formation

    NARCIS (Netherlands)

    Bartels-Velthuis, A. A.; Blijd-Hoogewys, E. M. A.; van Os, J.

    2011-01-01

    Objective: To examine the social cognitive vulnerabilities mediating delusion formation in children presenting with hallucinatory experiences. Method: A sample of 259 12- and 13-year-old children, from a baseline case-control sample of children with and without auditory hallucinations (AH), were re-

  17. Validity of the Career Decision-Making Difficulties Questionnaire: Counselee versus Career Counselor Perceptions.

    Science.gov (United States)

    Gati, Itamar; Osipow, Samuel H.; Krausz, Mina; Saka, Noa

    2000-01-01

    Data from 95 career counseling clients and from their counselors supported the validity of the Career Decision Making Difficulties Questionnaire. Compared with a sample of 259 young adults, counselees had significantly fewer difficulties related to motivation but more difficulties in six other categories. (SK)

  18. Comparison of Biomass and Lipid Production under Ambient Carbon Dioxide Vigorous Aeration and 3% Carbon Dioxide Condition Among the Lead Candidate Chlorella Strains Screened by Various Photobioreactor Scales

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Naoko [Univ. of Nebraska, Lincoln, NE (United States); Barnes, Austin [Univ. of Nebraska, Lincoln, NE (United States); Jensen, Travis [Univ. of Nebraska, Lincoln, NE (United States); Noel, Eric [Univ. of Nebraska, Lincoln, NE (United States); Andlay, Gunjan [Synaptic Research, Baltimore, MD (United States); Rosenberg, Julian N. [Johns Hopkins Univ., Baltimore, MD (United States); Betenbaugh, Michael J. [Johns Hopkins Univ., Baltimore, MD (United States); Guarnieri, Michael T. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Oyler, George A. [Univ. of Nebraska, Lincoln, NE (United States); Johns Hopkins Univ., Baltimore, MD (United States); Synaptic Research, Baltimore, MD (United States)

    2015-09-01

    Chlorella species from the UTEX collection, classified by rDNA-based phylogenetic analysis, were screened based on biomass and lipid production in different scales and modes of culture. Lead candidate strains of C. sorokiniana UTEX 1230 and C. vulgaris UTEX 395 and 259 were compared between conditions of vigorous aeration with filtered atmospheric air and 3% CO2 shake-flask cultivation. We found that the biomass of UTEX 1230 produced 2 times higher at 652 mg L-1 dry weight under both ambient CO2 vigorous aeration and 3% CO2 conditions, while UTEX 395 and 259 under 3% CO2 increased to 3 times higher at 863 mg L-1 dry weight than ambient CO2 vigorous aeration. The triacylglycerol contents of UTEX 395 and 259 increased more than 30 times to 30% dry weight with 3% CO2, indicating that additional CO2 is essential for both biomass and lipid accumulation in UTEX 395 and 259.

  19. Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study

    DEFF Research Database (Denmark)

    Pott, Christiane; Hoster, Eva; Delfau-Larue, Marie-Helene

    2010-01-01

    The prognostic impact of minimal residual disease (MRD) was analyzed in 259 patients with mantle cell lymphoma (MCL) treated within 2 randomized trials of the European MCL Network (MCL Younger and MCL Elderly trial). After rituximab-based induction treatment, 106 of 190 evaluable patients (56...

  20. Gclust Server: 87070 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 87070 Pst_PSPTO_1187 Cluster Sequences Related Sequences(259) 306 oxidoreductase, s...hort chain dehydrogenase/reductase family 1 1.00e-19 0.0 0.0 0.0 0.0 3.23 0.0 Show 87070 Cluster ID 87070 Se

  1. China-ASEAN,More Potential to Explore

    Institute of Scientific and Technical Information of China (English)

    Yang Wei

    2008-01-01

    @@ China-ASEAN bilateral trade maintained rapid growth for many years.Trade volume between China and the Association of Southeast Asian Nations (ASEAN)hit US$202.6 billion in 2007, up 25.9 percent year-on-year, according to the statistics from the China-ASEAN Business Council.

  2. Poverty as a Predictor of 4-Year-Olds' Executive Function: New Perspectives on Models of Differential Susceptibility

    Science.gov (United States)

    Raver, C. Cybele; Blair, Clancy; Willoughby, Michael

    2013-01-01

    In a predominantly low-income, population-based longitudinal sample of 1,259 children followed from birth, results suggest that chronic exposure to poverty and the strains of financial hardship were each uniquely predictive of young children's performance on measures of executive functioning. Results suggest that temperament-based vulnerability…

  3. Data of evolutionary structure change: 1LCTA-1JQFA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available Chain>A 1LCTA LYLGS--GYFTA ure...1LCTA-1JQFA 1LCT 1JQF A A -RSVQWCAVSNPEATKCFQWQRNMRKV---RGPPVSCIK...l> 0 1LCT A 1LCT...A NMRKV---RGPPV ure>...HHHH --- ure> ATOM 171 CA ASN A 25 4.724 22.416 67.259 1.00 20.95

  4. Data of evolutionary structure change: 1LCTA-1BP5D [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available A 1LCTA LFGSPSGQKDL ...1LCTA-1BP5D 1LCT 1BP5 A D RSVQWCAVSNPEATKCFQWQRNMRKV---RGPPVSCIKR...t> 0 1LCT A 1LCT...A NMRKV---RGPPV ...ure>HHHH --- ure> ATOM 171 CA ASN A 25 4.724 22.416 67.259 1.0

  5. Data of evolutionary structure change: 1LCTA-1A8EA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available dbID> A 1LCTA LYLGS--GYFTA ...1LCTA-1A8EA 1LCT 1A8E A A -RSVQWCAVSNPEATKCFQWQRNMRKV---RGPPVSCIK...nt> 0 1LCT A 1LCT...A NMRKV---RGPPV ...ure>HHHH --- ure> ATOM 171 CA ASN A 25 4.724 22.416 67.259 1.

  6. Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions.

    Science.gov (United States)

    Jaumot, M; Hancock, J F

    2001-07-01

    Raf-1 activation is a complex process which involves plasma membrane recruitment, phosphorylation, protein-protein and lipid-protein interactions. We now show that PP1 and PP2A serine-threonine phosphatases also have a positive role in Ras dependent Raf-1 activation. General serine-threonine phosphatase inhibitors such sodium fluoride, or ss-glycerophosphate and sodium pyrophosphate, or specific PP1 and PP2A inhibitors including microcystin-LR, protein phosphatase 2A inhibitor I(1) or protein phosphatase inhibitor 2 all abrogate H-Ras and K-Ras dependent Raf-1 activation in vitro. A critical Raf-1 target residue for PP1 and PP2A is S259. Serine phosphatase inhibitors block the dephosphorylation of S259, which accompanies Raf-1 activation, and Ras dependent activation of mutant Raf259A is relatively resistant to serine phosphatase inhibitors. Sucrose gradient analysis demonstrates that serine phosphatase inhibition increases the total amount of 14-3-3 and Raf-1 associated with the plasma membrane and significantly alters the distribution of 14-3-3 and Raf-1 across different plasma membrane microdomains. These observations suggest that dephosphorylation of S259 is a critical early step in Ras dependent Raf-1 activation which facilitates 14-3-3 displacement. Inhibition of PP1 and PP2A therefore causes plasma membrane accumulation of Raf-1/14-3-3 complexes which cannot be activated.

  7. The Relationship of Resilience with Attitude toward Grief in University Students

    Science.gov (United States)

    Celik, Seher Balci

    2013-01-01

    The purpose of this study is to reveal whether university students' level of resilience differ by gender and attitude toward grief, and to identify to what extent resilience predicts attitude toward grief. 259 students studying at Ondokuz Mayis University participated in the study. The average age of the participants was 20.27 plus or minus 1.19.…

  8. Results of the Cord Blood Transplantation Study (COBLT) : clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies

    NARCIS (Netherlands)

    Kurtzberg, Joanne; Prasad, Vinod K.; Carter, Shelly L.; Wagner, John E.; Baxter-Lowe, Lee Ann; Wall, Donna; Kapoor, Neena; Guinan, Eva C.; Feig, Stephen A.; Wagner, Elizabeth L.; Kernan, Nancy A.

    2008-01-01

    Outcomes of unrelated donor cord blood transplantation in 191 hematologic malignancy children (median age, 7.7 years; median weight, 25.9 kg) enrolled between 1999 and 2003 were studied (median follow-up, 27.4 months) in a prospective phase 2 multicenter trial. Human leukocyte antigen (HLA) matching

  9. Domain Modeling: NP_066574.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_066574.2 chr2 CRYSTAL STRUCTURE OF A DESIGNED ZINC FINGER PROTEIN BOUND TO DNA c1meyf_ chr2/NP_066574....2/NP_066574.2_holo_254-335.pdb blast 255K,259C,261E,262C,263G,264K,265A,266F,267F,268D

  10. EST Table: DN237655 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DN237655 EST00781 10/09/29 95 %/259 aa ref|NP_001037309.1| vitellogenin precursor [...s: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [Bombyx mori

  11. Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study

    DEFF Research Database (Denmark)

    Pott, Christiane; Hoster, Eva; Delfau-Larue, Marie-Helene;

    2010-01-01

    The prognostic impact of minimal residual disease (MRD) was analyzed in 259 patients with mantle cell lymphoma (MCL) treated within 2 randomized trials of the European MCL Network (MCL Younger and MCL Elderly trial). After rituximab-based induction treatment, 106 of 190 evaluable patients (56%) a...

  12. A matemática no projeto ciência na escola: a busca da autonomia dos alunos/The mathematics in the school science project...

    Directory of Open Access Journals (Sweden)

    Claudinei de Camargo Sant' Ana

    Full Text Available SANT’ANA, C. C. A matemática no projeto ciência na escola: a busca da autonomia dos alunos. 2008. 259fl. Tese (Doutorado em Educação – Faculdade de Educação, Universidade Estadual de Campinas, Campinas. 2008.

  13. Symptom Clusters among Young Adolescents.

    Science.gov (United States)

    Knishkowsky, Barry; And Others

    1995-01-01

    Examines recurrent psychosomatic symptoms and symptom clusters among Israeli school children (n=259). Results of a questionnaire that asked about the frequency of 8 psychosomatic and 8 organic complaints indicated that girls had a higher prevalence than boys for 8 of the symptoms, and that abdominal pain and headache were each reported as an…

  14. 76 FR 31467 - Guide Concerning Fuel Economy Advertising for New Automobiles

    Science.gov (United States)

    2011-06-01

    ... CFR Part 259 Guide Concerning Fuel Economy Advertising for New Automobiles AGENCY: Federal Trade... Advertising for New Automobiles (``Fuel Economy Guide'' or ``Guide'') pending completion of ongoing review by... prevent deceptive fuel economy advertising for new automobiles and to facilitate the use of fuel...

  15. Intentions to Participate in Counselling among Front-Line, At-Risk Irish Government Employees: An Application of the Theory of Planned Behaviour

    Science.gov (United States)

    Hyland, Philip E.; McLaughlin, Christopher G.; Boduszek, Daniel; Prentice, Garry R.

    2012-01-01

    The study set out to examine intentions to engage in counselling among at-risk Irish government employees and the differential utility of two alternative theory of planned behaviour (TPB) models of behaviour to explain intentions to participate in counselling. Individuals (N = 259) employed in a front-line, at-risk occupation for the Irish…

  16. Special Inspector General for Afghanistan Reconstruction. Quarterly Report to the United States Congress

    Science.gov (United States)

    2011-01-30

    quarter, Citibank announced that its Global Transaction Services division had entered into an agreement with the privately owned Afghanistan...fund transfers, according to Citibank .259 More than half of all Afghan civil servants now receive their salaries through electronic fund trans- fers

  17. Back-transformation of treatment differences - an approximate method

    DEFF Research Database (Denmark)

    Laursen, Rikke Pilmann; Dalskov, Stine-Mathilde; Damsgaard, Camilla Trab

    2014-01-01

    Background/Objectives:Transformation of outcomes is frequently used in the analysis of studies in clinical nutrition. However, back-transformation of estimated treatment means and differences is complicated by the nonlinear nature of the transformations. It is not straightforward to obtain an est...... publication, 11 December 2013; doi:10.1038/ejcn.2013.259....

  18. 76 FR 41150 - Notice Announcing Ten-Year Regulatory Review Schedule and Request for Public Comment on the...

    Science.gov (United States)

    2011-07-13

    ... the use of environmental marketing claims, in 2009 the Commission accelerated its review of its Guides for the Use of Environmental Marketing Claims, also known as the Green Guides, 16 CFR Part 260. In... Advertising for New Automobiles, 16 CFR Part 259; Guides for the Use of Environmental Marketing Claims, 16 CFR...

  19. Data of evolutionary structure change: 1MRUA-2BR1A [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1MRUA-2BR1A 1MRU 2BR1 A A TPSHLSDRYELGEILGFGGMSEVHLARDLRLHRDVAVKV... HHHHHHHHHH HHHH - HHHGGG- HHHH 0 1MRU... A 1MRUA EPPFT--GDSPV ARG CA 259 ARG CA 219 GLU CA 163 1MRU... A 1MRUA IVAVYDTG

  20. 76 FR 45181 - Enhancing Airline Passenger Protections: Limited Delay of Effective Date for Certain Provisions

    Science.gov (United States)

    2011-07-28

    ... Office of the Secretary 14 CFR Parts 244, 250, 253, 259 and 399 RIN No. 2105-AD92 Enhancing Airline... certain requirements adopted in an April 25, 2011 final rule on enhancing airline passenger protections... boarding compensation airlines must pay to passengers bumped from flights, and the requirement to disclose...

  1. 75 FR 36300 - Enhancing Airline Passenger Protections

    Science.gov (United States)

    2010-06-25

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF TRANSPORTATION Office of the Secretary 14 CFR Parts 234, 244, 250,253, 259, and 399 RIN 2105-AD92 Enhancing Airline... Airline Passenger Protections (75 FR 32318), which, among other things, solicits comment, without...

  2. Data of evolutionary structure change: 1CEVE-2RLAC [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1CEVE-2RLAC 1CEV 2RLA E C MKPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERL...A 241 TYR CA 259 SER CA 285 PRO CA 331 2RLA... C 2RLAC KFPDVPGFS...VAL CA 481 HIS CA 567 LEU CA 571 2RLA... C 2RLAC LLGRKKRPIHL

  3. Data of evolutionary structure change: 1CEVD-2RLAB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1CEVD-2RLAB 1CEV 2RLA D B MKPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERL...CA 242 TYR CA 259 SER CA 286 PRO CA 332 2RLA... B 2RLAB KFPDVPGF...e> VAL CA 481 HIS CA 562 LEU CA 570 2RLA... B 2RLAB LLGRKKRPIHL

  4. Data of evolutionary structure change: 1CEVE-2RLAB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1CEVE-2RLAB 1CEV 2RLA E B MKPISIIGVPMDLGQTRRGVDMGPSAMRYAGVIERLERL...A 241 TYR CA 259 SER CA 285 PRO CA 331 2RLA... B 2RLAB KFPDVPGFS...e> VAL CA 481 HIS CA 567 LEU CA 571 2RLA... B 2RLAB LLGRKKRPIHL

  5. The symmetry problem in $NaV_{2}O_{5}$

    NARCIS (Netherlands)

    Damascelli, A.; Marel, D. van der; Jegoudez, J.; Dhalenne, G.; Revcolevschi, A.

    1998-01-01

    Published in: Physica B 259-261 (1999) 978-980 citations recorded in [Science Citation Index] Abstract: We discuss the symmetry of NaV2O5 in the high temperature phase on the basis of optical conductivity data. Conclusive information cannot be obtained by studying the optically allowed lattice vibra

  6. Reading Motivation in Two Languages: An Examination of EFL College Students in Korea

    Science.gov (United States)

    Kim, Kyung Ja

    2011-01-01

    This study was designed to identify underlying factors that motivate language learners to read in a foreign language (L2) context. It also examined the relationships between L1 and L2 reading motivation and any differences in reading motivation based on the learners' academic majors and L2 reading proficiency. 259 Korean EFL college students…

  7. Eestlased riisusid Balti fotovõistlusel koore

    Index Scriptorium Estoniae

    2011-01-01

    Eesti, Läti ja Leedu fotovõistlusest, kus valiti Baltikumi parimad loodusfotod ja maaelu kajastavad fotod. Osales 259 fotograafi. Parim loodusfoto oli Kaido Haageni "Kus sa oled, mu sõber" ning parim foto maaelu kategoorias Arne Aderi "Jõuluks koju"

  8. Sublethal Ciprofloxacin Treatment Leads to Rapid Development of High-Level Ciprofloxacin Resistance during Long-Term Experimental Evolution of Pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    Jørgensen, Karin Meinike; Wassermann, Tina; Jensen, Peter Østrup

    2013-01-01

    lineages after 240 generations. The genetic basis of resistance was mutations in gyrA (C248T and G259T) and gyrB (C1397A). Cross-resistance to beta-lactam antibiotics was observed in the bacterial populations that evolved during exposure to sublethal concentrations of ciprofloxacin. Our study shows...

  9. Pneumococcal carriage in children in The Netherlands: a molecular epidemiological study

    NARCIS (Netherlands)

    D. Bogaert (Debby); M.N. Engelen (Marlene); A.J. Timmers-Reker; K.P. Elzenaar; P.G. Peerbooms; R.A. Coutinho (Roel); R. de Groot (Ronald); P.W.M. Hermans (Peter)

    2001-01-01

    textabstractIn 1999, Engelen and coworkers investigated colonization in Amsterdam among 259 children attending 16 day-care centers (DCCs) and among 276 children who did not attend day-care centers (NDCCs). A 1.6- to 3.4-fold increased risk for nasopharyngeal colonization was observ

  10. 40 CFR 35.250 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... ASSISTANCE Environmental Program Grants Pesticide Program Implementation (section 23(a)(1)) § 35.250 Purpose. (a) Purpose of section. Sections 35.250 through 35.259 govern Pesticide Program Implementation Cooperative Agreements to States (as defined in section 2 of Federal Insecticide, Fungicide, and...

  11. Risk factors for Clostridium difficile infection in the community

    DEFF Research Database (Denmark)

    Søes, Lillian Marie; Holt, H M; Böttiger, B

    2014-01-01

    SUMMARY To identify risk factors for Clostridium difficile infection (CDI) in Danish patients consulting general practice with gastrointestinal symptoms, a prospective matched case-control study was performed; cases (N = 259) had positive cultures for toxigenic C. difficile and controls (N = 455...

  12. How do lay people assess the quality of physicians' communicative responses to patients' emotional cues and concerns? An international multicentre study based on videotaped medical consultations.

    NARCIS (Netherlands)

    Mazzi, M.A.; Bensing, J.; Rimondini, M.; Fletcher, I.; Vliet, L. van; Zimmermann, C.; Deveugele, M.

    2013-01-01

    Objective: To establish which kind of physician communicative responses to patient cues and concerns are appreciated by lay people. Methods: A balanced sample (259 people) was recruited in public places to participate in a full day observation of four videotaped standardized medical consultations. I

  13. Sourcing in Professional Education: Do Text Factors Make Any Difference?

    Science.gov (United States)

    Bråten, Ivar; Strømsø, Helge I.; Andreassen, Rune

    2016-01-01

    The present study investigated the extent to which the text factors of source salience and emphasis on risk might influence readers' attention to and use of source information when reading single documents to make behavioral decisions on controversial health-related issues. Participants (n = 259), who were attending different bachelor-level…

  14. Jaan Tõnissoniga kakskümmend aastat tagasi : [art.] / Ain Kaalep

    Index Scriptorium Estoniae

    Kaalep, Ain, 1926-

    1997-01-01

    Ilm.: Edasi 1988, 12. november, nr. 259, lk. 4-5. Tekst ilmub täiendatult. A. Kaalep oma Jaan Tõnissonile pühendatud luuletustest "Romansid Don Quijotest, mis Cide Hamete Benengeli pühendas Don Juan de Trillo, Dianogada hertsogi õndsale mälestusele", ilmunud kogus "Klaasmaastikud" (Tallinn : Eesti Raamat, 1971)

  15. Distinguishing Complicated from Uncomplicated Bacteremia Caused by Staphylococcus aureus: The Value of "New" and "Old" Serological Tests

    NARCIS (Netherlands)

    H.A. Verbrugh (Henri); W.H.F. Goessens (Wil); M.F. Michel; R. Peters (Roel)

    1986-01-01

    textabstractAntibody responses to staphylococcal α-toxin, cell wall teichoic acid, and cell wall peptodoglycan were measured in 259 serum samples from 74 consecutive patients with Staphylococcus aureus bacteremia. All patients with complicated bacteremia were seropositive in at least one of three te

  16. The Predictive Value of Selected Extrinsic and Intrinsic Indicators of Overall Job Satisfaction in Diagnostic Radiological Technology, Radiation Therapy, and Nuclear Medicine Technology Allied Health Faculty

    Science.gov (United States)

    Beavers, Gregory S.

    2010-01-01

    Healthcare is the largest industry in the United States and 60 percent of its 14 million workers are in allied health jobs. The need to attract and retain allied health faculty is critical to preparing a competent workforce in healthcare. This study reports the results of a survey of 259 faculty members working in diagnostic radiologic technology,…

  17. Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older hispanics

    Science.gov (United States)

    Background: A common polymorphism, C776G, in the plasma B12 transport protein transcobalamin (TC), encodes for either proline or arginine at codon 259. This polymorphism may affect the affinity of TC for B12 and subsequent delivery of B12 to tissues. Methods: TC genotype and its associations with i...

  18. AcEST: DK961837 [AcEST

    Lifescience Database Archive (English)

    Full Text Available anio rerio GN=fam110b ... 31 6.8 sp|O88737|BSN_MOUSE Protein bassoon OS=Mus musculus GN=Bsn PE=1 ... 31 6.8 ... Sbjct: 259 ERE 261 >sp|O88737|BSN_MOUSE Protein bassoon OS=Mus musculus GN=Bsn PE=1 SV=3 Length = 3942 Scor

  19. A Methodological Approach for Conducting a Business Case Analysis (BCA) of the Global Observer Joint Capability Technology Demonstration (JCTD)

    Science.gov (United States)

    2007-12-01

    both the Allied and the Central Powers in scouting and observation roles . Airships were also deployed by the U.S. during World War II in Anti...John Wiley and Sons, Inc., 1995. 257-259. [37] L. Page, “US Special Ops Buys Hydrogen Droid Strato -comms Tech,” The Register, October 2, 2007

  20. Evaluation of antidiabetic potentials of Phyllanthus niruri in alloxan ...

    African Journals Online (AJOL)

    PRECIOUS

    African Journal of Biotechnology Vol. 9 (2), pp. 248-259, 11 January, 2010. Available ... The antidiabetic potentials of methanol extract (ME) of aerial parts of Phyllanthus niruri L ... against the control groups where there was evidence of necrosis. ... INTRODUCTION ...... hyperglycaemia in DM is a risk factor constantly fuelled.

  1. GETDB: 113428 [GETDB

    Lifescience Database Archive (English)

    Full Text Available iform epi, tr. proximal crescent in leg, initially ubiquitous. wg margin, leg - - comment1:C, comment2:59B2-...l crescent in leg, Adult GFP initially ubiquitous. wg margin, leg Lethality - Also known as - Original Comments comment1:C, comment

  2. Myers-Briggs Psychological Type and Achievement in Anatomy and Physiology.

    Science.gov (United States)

    Harasym, P. H.; And Others

    1995-01-01

    Results from the Myers-Briggs Type Indicator (MBTI) for 259 nursing students were compared with achievement on examinations in an anatomy and physiology course. Factor analysis demonstrated no relationship between examination scores and any of the individual personality traits purported to be measured by MBTI. Analysis of variance revealed no…

  3. Psycho-Social Influences on the Accomplishments of Mexican-American Students.

    Science.gov (United States)

    MacCorquodale, Patricia

    The accomplishments of Mexican American students have been limited by the level of education completed and by concentration in particular occupations. As part of a larger research project concerning this problem, 259 eighth grade students from Tucson were compared on the basis of sex and ethnicity, with a focus on attitudes toward science. No…

  4. Ground Combat Training Squadron Complex Final Environmental Assessment

    Science.gov (United States)

    2011-08-01

    Activities Areas of natural terrain with a thick understory and layers of heavy forest floor litter are important training components. Supervised...headquarters, aid and litter team, prisoner team, surveillance team, enroute recorder, compass person, and pace person. Description of the Proposed...Chapter 259 The proposed action would not affect Authorizes acquisition of Land Arquisitionfbr tourism and/or outdoor recreation. environmentally

  5. Production of secreted guar α-galactosidase by Lactococcus lactis

    NARCIS (Netherlands)

    Leenhouts, K.J.; Bolhuis, A.; Ledeboer, A.; Venema, G.; Kok, J.

    1995-01-01

    A plant α-galactosidase gene was inserted in the expression vector pGKV259. The resulting plasmid pGAL2 consisted of the replication functions of the broad-host-range lactococcal plasmid pWV01, the lactococcal promoter P59, and the DNA sequences encoding the α-amylase signal sequence from Bacillus a

  6. Production of secreted guar alpha-galactosidase by Lactococcus lactis

    NARCIS (Netherlands)

    Leenhouts, KJ; Bolhuis, A; Ledeboer, A; Venema, G; Kok, J

    1995-01-01

    A plant alpha-galactosidase gene was inserted in the expression vector pGKV259. The resulting plasmid pGAL2 consisted of the replication functions of the broad-host-range lactococcal plasmid pWVO1, the lactococcal promoter P59, and the DNA sequences encoding the alpha-amylase signal sequence from Ba

  7. Predictors of Success for Allied Health Students.

    Science.gov (United States)

    Jensen, Steven C.

    1989-01-01

    A study of 424 allied health students (259 dental hygiene, 104 radiologic technology, and 61 respiratory therapy) found that the greater predictors of their academic success were the natural science subscore on the American College Test (ACT), high school grade point average, and class rank, age, and composite ACT score. (SK)

  8. ROCKS & MINERALS DETERMINATION AND ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    <正>20070252 Chen Meilan (Biological and Environmental College, Zhejiang Shuren University, Hangzhou 310015, China); Li Li Study on Adsorption of Phenol by Modified Organobentonite (Rock and Mineral Analysis, ISSN0254-5357, CN11-2131/TD, 24(4), 2005, p.259-261, 267, 6 illus., 1 table, 11 refs.) Key words: bentonite, benzene, adsorption

  9. Current Trends in Educational Technology Research in Turkey in the New Millennium

    Science.gov (United States)

    Simsek, Ali; Ozdamar, Nilgun; Uysal, Omer; Kobak, Kadriye; Berk, Cem; Kilicer, Tugba; Cigdem, Harun

    2009-01-01

    This study examined 259 master's theses in the field of educational technology completed in Turkey during 2000-2007. The results suggested that quantity and quality of educational technology research varied according to years and universities. A great majority of the theses employed quantitative paradigm, and qualitative studies made about one…

  10. Domain Modeling: NP_958431.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NSTRUCTION OF AN ATOMIC MODEL FOR TROPOMYOSIN AND IMPLICATIONS FOR INTERACTIONS WITH ACTIN c2tmab_ chr17/NP_958431.2/NP_958431.2_apo_259-509.pdb psi-blast 0 ... ...NP_958431.2 chr17 TROPOMYOSIN CRYSTAL STRUCTURE AND MUSCLE REGULATION. APPENDIX. CO

  11. Gclust Server: 1988 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 1988 PTR_29658 Cluster Sequences Related Sequences(154) 259 estExt_Genewise1.C_chr_...180055 43 1.00e-99 85.71 66.67 0.0 0.0 0.0 87.5 Show 1988 Cluster ID 1988 Sequence ID PTR_29658 Link to clus

  12. Neurotransmitter Amines in Hemorrhagic Shock.

    Science.gov (United States)

    1984-03-02

    the vascular effect we have observed, nifedipine is preventing an influx of Ca++ into the cytosol. Lehninger 7) has called attention to the fact that...Neurochitur 63:259-265, 1982. 17. Lehninger AL: Role of phosphate and other proton donating cations in respiration-coupled transport of Ca++ by

  13. Carbon Tetrachloride Increases Intracellular Calcium in Rat Liver and Hepatocyte Cultures

    Science.gov (United States)

    1986-05-12

    Lehninger ~~., 1967). Although mitochondria provide a relatively high capacity Ca++ sink, the affinity of this pump for Ca ++ is much less that of the Ca... Lehninger , A. L., E. Carafoli, and c. s. Rossi. (1967) Energy-Linked Ion Movements in Mitochondrial Systems. Adv. Enzymology 29:259-320. Lowry, O. H

  14. Nasal Staphylococcus aureus and methicillin-resistant Staphylococcus aureus carriage among college student athletes in northern Taiwan

    Directory of Open Access Journals (Sweden)

    Hong-Kai Wang

    2017-08-01

    Full Text Available Of 259 college students in northern Taiwan surveyed, nasal carriage rate of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA was 22.4% and 1.54%, respectively and no significant difference was found between athlete students and non-athlete students. Three of four MRSA isolates belonged to sequence type 59, the endemic community clone.

  15. Myocardial scintigraphy. Clinical use and consequence in a non-invasive cardiological department

    DEFF Research Database (Denmark)

    Dümcke, Christine Elisabeth; Graff, J; Rasmussen, SPL

    2006-01-01

    to analyse the clinical use of MPI in a university hospital without invasive cardiological laboratory. MATERIAL AND METHODS: In the period 01.01.2002 to 31.12.2003, 259 patients (141 women, 118 men) were referred to MPI from our department of cardiology. RESULTS: Normal MPI was seen in 111 patients (43...

  16. Excellence in higher education: educational preferences of honours students in the Netherlands

    NARCIS (Netherlands)

    Kolster, Renze; van Dijk, Lisa; Jongbloed, Benjamin W.A.

    2016-01-01

    This paper researches excellence in higher education by looking into honours programmes (HPs) in Dutch higher education. HPs are selective and aimed at the brightest students, offering them a more challenging – often extra-curricular – study experience. Based on a survey (n=259) at Dutch

  17. 46 CFR 401.110 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... to provide pilotage services. (15) Comparable experience means experience that is similar to the... § 401.110 Definitions. (a) As used in this chapter: (1) Act means the Great Lakes Pilotage Act of 1960, as amended (Pub. L. 86-555, 74 Stat. 259-262; 46 U.S.C. 216 through 216i). (2) Commandant means...

  18. A Survey of Exemplar Teachers' Perceptions, Use, and Access of Computer-Based Games and Technology for Classroom Instruction

    Science.gov (United States)

    Proctor, Michael D.; Marks, Yaela

    2013-01-01

    This research reports and analyzes for archival purposes surveyed perceptions, use, and access by 259 United States based exemplar Primary and Secondary educators of computer-based games and technology for classroom instruction. Participating respondents were considered exemplary as they each won the Milken Educator Award during the 1996-2009…

  19. Surveying the Dynamic Radio Sky with the Long Wavelength Demonstrator Array

    Science.gov (United States)

    2010-10-01

    this observational program. As DeGroot (1986) discusses, the probability of ob- taining i detections in N trials, given that the de- tection probability...145; http://www.ece.vt.edu/swe/lwa/lwa0145.pdf Dagkesamanskij, R. D., & Zheleznykh, I. M. 1989, JETP Lett., 50, 259 (translated from Russian) DeGroot

  20. Operational test report for 2706-T complex liquid transfer system

    Energy Technology Data Exchange (ETDEWEB)

    BENZEL, H.R.

    1999-09-01

    This document is the Operational Test Report (OTR). It enters the Record Copy of the W-259 Operational Test Procedure (HNF-3610) into the document retrieval system. Additionally, the OTR summarizes significant issues associated with testing the 2706-T waste liquid transfer and storage system.

  1. Eestlased riisusid Balti fotovõistlusel koore

    Index Scriptorium Estoniae

    2011-01-01

    Eesti, Läti ja Leedu fotovõistlusest, kus valiti Baltikumi parimad loodusfotod ja maaelu kajastavad fotod. Osales 259 fotograafi. Parim loodusfoto oli Kaido Haageni "Kus sa oled, mu sõber" ning parim foto maaelu kategoorias Arne Aderi "Jõuluks koju"

  2. Escitalopram in the Treatment of Adolescent Depression: A Randomized Placebo-Controlled Multisite Trial

    Science.gov (United States)

    Emslie, Graham J.; Ventura, Daniel; Korotzer, Andrew; Tourkodimitris, Stavros

    2009-01-01

    A randomized, double-blind, placebo-controlled trial that involves 312 male and female patients aged 12-17 reveal the effectiveness of escitalopram in the treatment of depressed adolescents. Eighty-three percent of the participants or 259 participants completed the 8 weeks therapy period.

  3. AFRREV STECH, Vol. 3(2) May, 2014

    African Journals Online (AJOL)

    Toshiba

    2014-05-07

    May 7, 2014 ... ... 2014: 259-268. ISSN 2225-8612 (Print) ISSN 2227-5444 (Online) ... used in the educational technology sector, ICTs as a vehicle for economic ... Information and communication technology provides a platform for people to ...

  4. Domain Modeling: NP_776173.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE p2wita_ chr12/NP_776173.3/NP_776173.3_holo_80-636.pdb swppa 252L,254G,255L,256M,258G,259L,270T,335V,402L,403L,440L BET 0 ...

  5. Domain Modeling: NP_001254.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available BETP FROM CORYNEBACTERIUM GLUTAMICUM WITH BOUND SUBSTRATE p2wita_ chr4/NP_001254.2/NP_001254.2_holo_82-458.pdb swppa 147W,148Y,149F,150L,152C,169F,173E,186I,250I,259F,264G,265R BET 0 ...

  6. Featuring Old/New Recognition: The Two Faces of the Pseudoword Effect

    Science.gov (United States)

    Joordens, Steve; Ozubko, Jason D.; Niewiadomski, Marty W.

    2008-01-01

    In his analysis of the pseudoword effect, [Greene, R.L. (2004). Recognition memory for pseudowords. "Journal of Memory and Language," 50, 259-267.] suggests nonwords can feel more familiar that words in a recognition context if the orthographic features of the nonword match well with the features of the items presented at study. One possible…

  7. Parenting and Family Stress as Mediators of the Long-Term Effects of Child Abuse.

    Science.gov (United States)

    Wind, Tiffany Weissmann; Silvern, Louise

    1994-01-01

    Data on child physical/sexual abuse, family stress histories, perceived parental warmth, and current psychological functioning were gathered from 259 working women. Multiple regression analyses showed that parental warmth strongly influenced or mediated the relationship of intrafamilial child abuse to depression and self-esteem levels. However,…

  8. United States Air Force Research Initiation Program for 1987. Volume 3

    Science.gov (United States)

    1989-04-01

    mi-nutes. The mi-xtire tu- ned a very dark red (almost black). The ice bath was removed and the mixture was allowed -o warm to room zemneraure over 25...9, 395 (1973). 2. C. T. Sun, J. D. Achenbach and G. Herrmann , J. Appl. Mech. 35, 467 (1968). 3. A. H. Nayfeh, "Acoustic Wave Reflection from Water

  9. Protein structure of fetal antigen 1 (FA1). A novel circulating human epidermal-growth-factor-like protein expressed in neuroendocrine tumors and its relation to the gene products of dlk and pG2

    DEFF Research Database (Denmark)

    Jensen, Charlotte Harken; Krogh, Thomas N; Højrup, Peter

    1994-01-01

    -growth-factor motifs and contains up to ten O-glycosylation and N-glycosylation sites, six of which are differentially glycosylated. Alignment to the translated sequences of Mus. musculus dlk and human dlk revealed 86% and 99% identity, respectively, to a 259-amino-acid residue overlap, and this high similarity...

  10. AcEST: DK955214 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 1891|MO25_DROME Protein Mo25 OS=Drosophila melanogaster GN=... 173 6e-43 sp|Q9XFY6|DEE76_CHLPR Degreening-re... Sbjct: 259 MMNMLKE 265 >sp|Q9XFY6|DEE76_CHLPR Degreening-related gene dee76 prot

  11. Mapping of industrial effluent on coastal sediments using EDX

    CSIR Research Space (South Africa)

    Gregory, MA

    2003-01-01

    Full Text Available ?165. [11] G.J.M. Copeland (1992). Water Sci. and Technol., 25(9), 189?195. [12] A.S. Arcilla, A. Rodriguez and M. Mestres (1998). J. Mar. Environ. Eng., 4, 217?243. [13] C.M.G. Vivian(1986). Sci. Total Environ., 53, 5?40. [14] G. Courtois (1967...

  12. Dasatinib or imatinib in newly diagnosed chronic-phase chronic myeloid leukemia : 2-year follow-up from a randomized phase 3 trial (DASISION)

    NARCIS (Netherlands)

    Kantarjian, Hagop M.; Shah, Neil P.; Cortes, Jorge E.; Baccarani, Michele; Agarwal, Mohan B.; Soledad Undurraga, Maria; Wang, Jianxiang; Kassack Ipina, Juan Julio; Kim, Dong-Wook; Ogura, Michinori; Pavlovsky, Carolina; Junghanss, Christian; Milone, Jorge H.; Nicolini, Franck E.; Robak, Tadeusz; Van Droogenbroeck, Jan; Vellenga, Edo; Bradley-Garelik, M. Brigid; Zhu, Chao; Hochhaus, Andreas

    2012-01-01

    Dasatinib is a highly potent BCR-ABL inhibitor with established efficacy and safety in imatinib-resistant/-intolerant patients with chronic myeloid leukemia (CML). In the phase 3 DASISION trial, patients with newly diagnosed chronic-phase (CP) CML were randomized to receive dasatinib 100 mg (n = 259

  13. Rural Principal Leadership Skill Proficiency and Student Achievement

    Science.gov (United States)

    Winn, Pam; Erwin, Sue; Gentry, Jim; Cauble, Mary

    2009-01-01

    Because of the importance of developing highly skilled rural school leaders, statewide assessments of 259 rural Texas public school administrators were analyzed to determine principal confidence levels in leadership skill domains identified by the National Policy Board of Educational Administration (NPBEA). Important findings indicate differences…

  14. The compounds of phenolic nature - new opportunities for pharmacological correction of endothelial dysfunction.

    Directory of Open Access Journals (Sweden)

    Mikhail V. Korokin

    2016-09-01

    Full Text Available Investigation of endotelioprotective effects of phenolic compounds containing directly related heteroatom, and heterocyclic structural fragments under laboratory code KUD259, KUD970, KUD971, KUD972, KUD973, KUD974, KUD975 and KUD976 in modeling L-NAME induced endothelial dysfunction.

  15. 255 effects of some heavy metal pollutants on fertility characteristics ...

    African Journals Online (AJOL)

    DR. AMINU

    2010-06-01

    Jun 1, 2010 ... Bayero Journal of Pure and Applied Sciences, 3(1): 255 - 259. Received: October ... Grid sampling was employed in which ... ten equally sized grid cells of 10m2. Samples .... and the first week of June when irrigation activities.

  16. Browse Title Index

    African Journals Online (AJOL)

    Items 101 - 150 of 259 ... Vol 17, No 4 (2011), Excess of non-verbal cases of autism ... Kiran Sukeri, Orlando A. Betancourt, Robin Emsley, Mohammed Nagdee, Helmut Erlacher ... Vol 20, No 4 (2014), Magnetic resonance imaging study of corpus ...

  17. Prevalence of Demodex spp among alcohol-dependent patients

    Directory of Open Access Journals (Sweden)

    Mehmet Hanifi Kokacya

    2016-06-01

    Conclusion: Demodex spp. are more common in alcohol-dependent patients due conditions of reduced self-care and immunosuppression. Demodex parasites should be considered in alcohol-dependent patients with skin lesions, especially on the face, and should to be treated if needed. [Cukurova Med J 2016; 41(2.000: 259-263

  18. Associations between Adolescents' Situational Motivation and Objectively-Determined Physical Activity Levels in Physical Education

    Science.gov (United States)

    Ning, Weihong; Pope, Zachary; Gao, Zan

    2015-01-01

    Purpose: This study aimed to examine the predictive strength of adolescents' situational motivation to their physical activity levels in physical education. Method: A total of 259 middle school students ranging from 11 to 14 years old participated in the study. Participants completed the Situational Motivation Scale in one class. Their PA levels…

  19. 75 FR 26299 - Self-Regulatory Organizations; Notice of Filing and Immediate Effectiveness of Proposed Rule...

    Science.gov (United States)

    2010-05-11

    .... 157 AMLN Amylin Pharmaceuticals Inc. 158 CTIC Cell Therapeutics Inc. 159 MDT Medtronic Inc. 162 TIVO... Devices Inc. 259 STT State Street Corp. 260 BHP BHP Billiton Ltd. 261 NFLX NetFlix Inc. 262 LDK LDK Solar...-mail is used. To help the Commission process and review your comments more efficiently, please use...

  20. The Role of Personal Attributes and Social Support Factors on Passive Behaviour in Classroom among Secondary School Students: A Prospective Study

    Science.gov (United States)

    Murberg, Terje A.

    2010-01-01

    The present study prospectively explored the effects of personal attributes (self-esteem and introversion) and social support factors on passive behaviour in the classroom in a sample of 259 (132 females, 127 males) students in two secondary schools. In the longitudinal multivariate analysis, the student's perceived passive behaviour in the…

  1. The Contribution of Counseling Providers to the Success or Failure of Marriages

    Science.gov (United States)

    Ansah-Hughes, Winifred

    2015-01-01

    This study is an investigation into the contribution of counseling providers to the success or failure of marriages. The purposive and the simple random sampling methods were used to select eight churches and 259 respondents (married people) in the Techiman Municipality. The instrument used to collect data was a 26-item questionnaire including a…

  2. 76 FR 70413 - National Fire Protection Association (NFPA): Request for Comments on NFPA's Codes and Standards

    Science.gov (United States)

    2011-11-14

    ... Systems Code P NFPA 67 Guideline on Explosion Protection for Gaseous N Mixtures in Pipe Systems. NFPA 68 Standard on Explosion Protection by Deflagration P Venting. NFPA 70B Recommended Practice for Electrical.... NFPA 259 Standard Test Method for Potential Heat of Building P Materials. NFPA 260 Standard Methods...

  3. Excellence in higher education: educational preferences of honours students in the Netherlands

    NARCIS (Netherlands)

    Kolster, Renze; van Dijk, Lisa; Jongbloed, Benjamin W.A.

    2016-01-01

    This paper researches excellence in higher education by looking into honours programmes (HPs) in Dutch higher education. HPs are selective and aimed at the brightest students, offering them a more challenging – often extra-curricular – study experience. Based on a survey (n=259) at Dutch universitie

  4. Analysis of Fixed Asset Investments in the First Half of 2007

    Institute of Scientific and Technical Information of China (English)

    Dong Tao

    2007-01-01

    @@ Fixed asset investment in China picked up mildly overall in the first half of 2007. growing 25.9% from January to June - 3.9 percentage points lower than the same period of 2006 and 2.2 percentage points higher than the first quarter of this year.

  5. Developing Human Embryonic Stem Cells for Grafting in Parkinson’s Disease

    Science.gov (United States)

    2007-03-01

    markers Oligodendrocyte markers Gap43, Nfh, Eno2 Th, Aadc, Dat Ngf Hoxc6 S100β, Cd68 Gfap, Tapa1 Mag, Mobp, Omg V. Distinct markers Normal...Derivation, growth and applications of human embryonic stem cells. Reproduction 128:259-267. Y. Takagi, J. Takahashi, H. Saiki, A. Morizane, T

  6. 76 FR 30978 - Employment and Training Administration Program Year (PY) 2011 Workforce Investment Act (WIA...

    Science.gov (United States)

    2011-05-27

    ...,253,180 for State service area grants; $5,688,600 for migrant and seasonal farmworker housing... Mexico 946,732 New York 1,656,708 North Carolina 2,690,959 North Dakota 607,492 Ohio 1,259,904 Oklahoma...

  7. The Effects of Changes in Racial Identity and Self-Esteem on Changes in African American Adolescents' Mental Health

    Science.gov (United States)

    Mandara, Jelani; Gaylord-Harden, Noni K.; Richards, Maryse H.; Ragsdale, Brian L.

    2009-01-01

    This study assessed the unique effects of racial identity and self-esteem on 259 African American adolescents' depressive and anxiety symptoms as they transitioned from the 7th to 8th grades (ages 12-14). Racial identity and self-esteem were strongly correlated with each other for males but not for females. For both males and females, an increase…

  8. Occupancy Grid Map Merging Using Feature Maps

    Science.gov (United States)

    2010-11-01

    Gonzalez, “Toward a unified bayesian approach to hybrid metric-topological SLAM,” IEEE Transactions on Robotics , 24(2), April 2008, 259-270. [14] G...Risetti, C. Stachniss, and W. Burgard, “Improved Techniques for grid mapping with Rao-Blackwellized Particle Filter,” IEEE Transactions on Robotics , 23

  9. AcEST: BP917978 [AcEST

    Lifescience Database Archive (English)

    Full Text Available IC6|VGLG_LNYV Glycoprotein G OS=Lettuce necrotic yellows v... 29 9.4 sp|A6VMF8|MEND_ACTSZ 2-succinyl-5-enolp...SPQKVVIENSWAFRNGINY 259 Query: 218 WKD 210 W D Sbjct: 260 WND 262 >sp|Q9DIC6|VGLG_LNYV Glycoprotein G OS=Lettuce

  10. Bidirectional Influences between Maternal Parenting and Children's Peer Problems: A Longitudinal Monozygotic Twin Difference Study

    Science.gov (United States)

    Yamagata, Shinji; Takahashi, Yusuke; Ozaki, Koken; Fujisawa, Keiko K.; Nonaka, Koichi; Ando, Juko

    2013-01-01

    This twin study examined the bidirectional relationship between maternal parenting behaviors and children's peer problems that were not confounded by genetic and family environmental factors. Mothers of 259 monozygotic twin pairs reported parenting behaviors and peer problems when twins were 42 and 48 months. Path analyses on monozygotic twin…

  11. Visual Clarity with a Black-and-White Scene

    Science.gov (United States)

    1984-03-30

    another on the basis that it somehow better revealed the detail. as seen by the subject. For "near" observations, a stool was provided near the...259- 261, 1969. 2. R. G. Hopkinson and J. B, Collins, The Ergonomics of Lighting (MacDonald, London, 1970). 𔃽. William A. Thornton and E. Chen

  12. Recent advances in the diagnosis of Cushing’s syndrome in dogs

    NARCIS (Netherlands)

    Kooistra, H.S.|info:eu-repo/dai/nl/205285864; Galac, S.|info:eu-repo/dai/nl/304830860

    2010-01-01

    Vet Clin North Am Small Anim Pract. 2010 Mar;40(2):259-67. Recent advances in the diagnosis of Cushing's syndrome in dogs. Kooistra HS, Galac S. Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM Utrecht, The Netherlands.

  13. Longitudinal Study of Human Hearing: Its Relationship to Noise and Other Factors 2. Results from the First Three Years

    Science.gov (United States)

    1979-11-01

    rural Illinois school system. Am. J. Dis. Child., 80: 254-259. Eagles, E. 1., S. M. Wishik, L. G. Doerfler , W. Melnick, and H. S. Levine 1963 Hearing...sensitivity and related factors in children. Laryngoscope, Monograph Suppl., 1-143. Eagles, E. L., S. M. Wishik, and L. G. Doerfler 1967 Hearing

  14. Results of the Cord Blood Transplantation Study (COBLT) : clinical outcomes of unrelated donor umbilical cord blood transplantation in pediatric patients with hematologic malignancies

    NARCIS (Netherlands)

    Kurtzberg, Joanne; Prasad, Vinod K.; Carter, Shelly L.; Wagner, John E.; Baxter-Lowe, Lee Ann; Wall, Donna; Kapoor, Neena; Guinan, Eva C.; Feig, Stephen A.; Wagner, Elizabeth L.; Kernan, Nancy A.

    2008-01-01

    Outcomes of unrelated donor cord blood transplantation in 191 hematologic malignancy children (median age, 7.7 years; median weight, 25.9 kg) enrolled between 1999 and 2003 were studied (median follow-up, 27.4 months) in a prospective phase 2 multicenter trial. Human leukocyte antigen (HLA) matching

  15. Reference: ACGTROOT1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available ACGTROOT1 Kim JC, Lee SH, Cheong YH, Yoo CM, Lee SI, Chun HJ, Yun DJ, Hong JC, Lee ...SY, Lim CO, Cho MJ A novel cold-inducible zinc finger protein from soybean, SCOF-1, enhances cold tolerance in transgenic plants Plant J 25: 247-259 (2001) PubMed: 11208017; ...

  16. Family Functioning Predictors of Self-Concept and Self-Esteem in Children at Risk for Learning Disabilities in Oman: Exclusion of Parent and Gender Contribution

    Science.gov (United States)

    Emam, Mahmoud Mohamed; Abu-Serei, Usama Saad

    2014-01-01

    The study investigated whether family functioning can predict the self-concept and self-esteem of normally achieving (NA) and at risk for learning disabilities (LD) students in Oman regardless of parent education level and gender status. A total of 259 elementary school students were selected from schools in the main districts of Muscat, the…

  17. Domain Modeling: NP_057507.2 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_057507.2 chr14 Aart, a six finger zinc finger designed to recognize ANN triplets... c2i13b_ chr14/NP_057507.2/NP_057507.2_holo_27-178.pdb psi-blast 254R,256A,257T,258P,259T,260P,263A,265P,276

  18. Domain Modeling: NP_001001662.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001001662.1 chr9 Aart, a six finger zinc finger designed to recognize ANN triple...ts c2i13b_ chr9/NP_001001662.1/NP_001001662.1_holo_111-259.pdb psi-blast 315Y,317K,318S,319F,320N,321R,322N,

  19. AJINT

    African Journals Online (AJOL)

    Key 1words: Anemia; CKD', Renal insufiiciencyi'enous thromboembolism. ... have L's-'T-I and that prevalence tended to reach 259i: by the initiation of the dialysis ... decline in kidney fimctionand the resulting heart failure can be devastating ...

  20. NEUROBEHAVIORAL RELATIONSHIPS AFTER THE ONSET OF PUBERTY

    NARCIS (Netherlands)

    SOORANILUNSING, RJ; HADDERSALGRA, M; HUISJES, HJ; TOUWEN, BCL

    1994-01-01

    The behavioural and cognitive development were studied of 68 children with and 259 without minor neurological function (MND) at 14 years, when the majority of children showed three or more physical signs of puberty. MND was differentiated into fine manipulative disability, co-ordination problems, ch

  1. Teenage Marriage and Marital Stability.

    Science.gov (United States)

    Bahr, Stephen J.; Galligan, Richard J.

    1984-01-01

    Hypothetically, earlier marriages are more likely to dissolve, but reasons for this are as yet unclear. A longitudinal analysis of a cohort of 259 couples revealed that those who married later, had more education, and did not experience unemployment, were more likely to remain in a stable marriage. (KH)

  2. An Investigation of Hope, Academics, Environment, and Motivation as Predictors of Persistence in Higher Education Online Programs

    Science.gov (United States)

    Holder, Bruce

    2007-01-01

    Predictors of persistence previously found useful in distinguishing successful from unsuccessful distance learners were assembled in a 60-item survey. The survey was completed by 259 learners enrolled in associate's, bachelor's, or master's level distance learning courses in accounting, business administration, information services, criminal…

  3. Youth Experience of Trying to Get off the Street: What Has Helped and Hindered

    Science.gov (United States)

    Brown, Tracy L.; Amundson, Norman E.

    2010-01-01

    This qualitative study involved 20 youth (18 males, 1 female, 1 transgender, ages 19-24) living in Vancouver, British Columbia, who reported 259 critical incidents of what helped or hindered their experiences as they tried to get off the street. What helped included (a) taking responsibility, (b) engaging in constructive activities, (c) friends…

  4. Better theory-of-mind skills in children hearing voices mitigate the risk of secondary delusion formation

    NARCIS (Netherlands)

    Bartels-Velthuis, A. A.; Blijd-Hoogewys, E. M. A.; van Os, J.

    Objective: To examine the social cognitive vulnerabilities mediating delusion formation in children presenting with hallucinatory experiences. Method: A sample of 259 12- and 13-year-old children, from a baseline case-control sample of children with and without auditory hallucinations (AH), were

  5. SALT spectroscopic classification of PS16fbb (= Gaia16bvg = SN 2016ick) as a type-Ia supernova at maximum light

    Science.gov (United States)

    Jha, S. W.; Dettman, K.; Pan, Y.-C.; Foley, R. J.; Rest, A.; Scolnic, D.; Kotze, M.

    2016-11-01

    We obtained SALT (+RSS) spectroscopy of PS16fbb (= Gaia16bvg = SN 2016ick) on 2016 Nov 25.9 UT, covering the wavelength range 340-920 nm. Emission and absorption lines from the anonymous host galaxy give a redshift z = 0.0525.

  6. Hepatoprotective Effect of Pandanus odoratissimus L Inflorescence ...

    African Journals Online (AJOL)

    Tropical Journal of Pharmaceutical Research February 2016; 15 (2): 259-266. ISSN: 1596-5996 (print); .... Malaysia; known by locals in India as Ketaki, is used in Ayurvedic .... Cobas C 311 analyzer (Roche Diagnostics -. GmbH, D-68298 ...

  7. European survey on sterigmatocystin in cereals, cereals-based products, beer and nuts

    NARCIS (Netherlands)

    Mol, H.G.J.; MacDonald, S.J.; Anagnostopoulos, C.; Spanjer, M.; Bertuzzi, T.; Pietri, A.

    2016-01-01

    Based on the EFSA proposal 'Survey on sterigmatocystin in food' (GP/EFSA/CONTAM/2013/02), this study provides a survey on the occurrence of this mycotoxin. A total of 1,259 samples of cereal grains (429), cereal products (713), beer (53) and nuts (64) were analysed for the presence of sterigmatoc

  8. Understanding the Roles of Design and Interaction Elements in the Context of Promoting Sustained Health App Usage | Smokefree.gov

    Science.gov (United States)

    As mobile technologies continue to advance and grow, the world of mobile health (mHealth) is seeing parallel growth. As of 2016, there are roughly 259,000 mHealth related apps available1.  Last year, Pew Research Center published a report on U.S.

  9. 75 FR 16493 - Announcement of Funding Awards for the Public and Indian Housing Family Self-Sufficiency Program...

    Science.gov (United States)

    2010-04-01

    ... Authority of Greene P.O. Box 336 325 White Hall...... IL 62092 45,910 County. North Carr. Housing Authority.... Parkway. Mobile Housing Board......... 151 South Claiborne Mobile AL 36602 47,259 Street. Tuscaloosa... P.O. Box 27210 310 Tucson AZ 85726 68,000 North Commerce Park Loop. Housing Authority City of...

  10. Ego Identity Status: A Step in the Differentiation Process.

    Science.gov (United States)

    Johnson, Patrick; Buboltz, Walter C., Jr.; Seemann, Eric

    2003-01-01

    Examines the relationship between identity development and differentiation levels in young adults. A total of 259 participants completed the Extended Version of the Objective Measure of Ego Identity Status, the Differentiation of Self Inventory, and demographic questions. Results showed that each identity status had a unique effect on the various…

  11. Does Eating Breakfast Affect the Performance of College Students on Biology Exams?

    Science.gov (United States)

    Phillips, Gregory W.

    2005-01-01

    This study examined the breakfast eating habits of 1,259 college students over an eleven year period to determine if eating breakfast had an impact upon their grade on a General Biology exam. The study determined that there was a significant difference in the performance on the exam with a higher percent of the participants, who had eaten…

  12. Overcoming alienation in Africanising theological education

    African Journals Online (AJOL)

    2016-02-22

    Feb 22, 2016 ... location of theology, secular philosophy and scientific reason and simultaneously .... the 'source' for the construction of that knowledge. Ramose ..... in the Room: Ethical Reflections on White Privilege and. Other Systems of .... epistemic intervention', South African Review of Sociology 37(2), 241–259. http://.

  13. Intentions to Participate in Counselling among Front-Line, At-Risk Irish Government Employees: An Application of the Theory of Planned Behaviour

    Science.gov (United States)

    Hyland, Philip E.; McLaughlin, Christopher G.; Boduszek, Daniel; Prentice, Garry R.

    2012-01-01

    The study set out to examine intentions to engage in counselling among at-risk Irish government employees and the differential utility of two alternative theory of planned behaviour (TPB) models of behaviour to explain intentions to participate in counselling. Individuals (N = 259) employed in a front-line, at-risk occupation for the Irish…

  14. Genetic Variation in the Leptin Receptor Gene, Leptin, and Weight Gain in Young Dutch Adults

    NARCIS (Netherlands)

    Rossum, van C.T.M.; Hoebee, B.; Baak, van M.A.; Mars, M.; Saris, W.H.M.; Seidell, J.C.

    2003-01-01

    Objective: To investigate the association between leptin levels, polymorphisms in the leptin receptor (LEPR) gene, and weight gain. Research Methods and Procedures: From two large prospective cohorts in The Netherlands (n = 17, 500), we compared the baseline leptin of 259 subjects who had gained an

  15. Paradoxical Effects of Warning in the Production of Children's False Memories

    Science.gov (United States)

    Del Prete, Francesco; Mirandola, Chiara; Konishi, Mahiko; Cornoldi, Cesare; Ghetti, Simona

    2014-01-01

    The effects of warning on false recognition and associated subjective experience of false recollection and familiarity were investigated in 7-to 13-year-old children and young adults (N = 259) using the Deese-Roediger-McDermott (DRM) paradigm. Two warning conditions (warning with an example of a critical lure and warning without an example of a…

  16. HANSENULA WICKERHAMII SP. N., A NEW YEAST FROM FINNISH SOIL

    Science.gov (United States)

    Capriotti, Augusto

    1961-01-01

    Capriotti, Augusto (l'Università di Perugia, Perugia, Italy). Hansenula wickerhamii sp. n., a new yeast from Finnish soil. J. Bacteriol. 82:259–360. 1961.—Hansenula wickerhamii sp. n. is described; it was isolated from a Finnish soil, and is named in honor of Lynferd J. Wickerham. Images PMID:13690638

  17. European activities in civil applications of drones: an overview of remotely piloted aircraft systems (RPAS)

    Science.gov (United States)

    Creutzburg, Reiner

    2015-05-01

    The aim of this paper is to give an overview of recent research, development and civil application of remotely piloted aircraft systems (RPAS) in Europe. It describes a European strategy for the development of civil applications of Remotely Piloted Aircraft Systems (RPAS) and reflects most of the contents of the European staff working document SWD(2012) 259 final.

  18. Sickness absence and return to work rates in women with breast cancer

    NARCIS (Netherlands)

    Roelen, Corne A. M.; Koopmans, Petra C.; de Graaf, Jan H.; Balak, Fulya; Groothoff, Johan W.

    2009-01-01

    Most women are diagnosed with breast cancer when they are of working age. How long are breast cancer patients absent? How many of them return to work? ArboNed Occupational Health Services documents sickness absence data of 1 million workers of whom 40% were women. Between 2001 and 2005, 2,259 women

  19. Relationship between Tobacco Advertising and Youth Smoking: Assessing the Effectiveness of a School-Based Antismoking Intervention Program.

    Science.gov (United States)

    Beltramini, Richard F.; Bridge, Patrick D.

    2001-01-01

    The Hazards of Tobacco (C) program, which focuses on smoking prevention among youth, was completed by 259 suburban sixth graders (199 controls) and 166 urban fifth through seventh graders. Participation significantly changed understanding of the role of tobacco advertising and the intention to smoke in both samples. (Contains 49 references.) (SK)

  20. Genetic Variation in the Leptin Receptor Gene, Leptin, and Weight Gain in Young Dutch Adults

    NARCIS (Netherlands)

    Rossum, van C.T.M.; Hoebee, B.; Baak, van M.A.; Mars, M.; Saris, W.H.M.; Seidell, J.C.

    2003-01-01

    Objective: To investigate the association between leptin levels, polymorphisms in the leptin receptor (LEPR) gene, and weight gain. Research Methods and Procedures: From two large prospective cohorts in The Netherlands (n = 17, 500), we compared the baseline leptin of 259 subjects who had gained an

  1. Cotton Demand Dropping in China

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    The ICAC claimed, global cotton market outlook is bleak in the 2012/2013 annual. Global cotton production is estimated at 25.9 million tons and cotton usage is estimated at 23.4 million tons. Cotton supply will exceed demand; the excess volume will reach 2.4 million tons.

  2. Browse Title Index

    African Journals Online (AJOL)

    Items 1 - 50 of 259 ... Vol 23, No 1 (2017), Adult attention-deficit hyperactivity disorder: A ... Vol 23, No 1 (2017), Alcohol use disorder and tuberculosis treatment: A longitudinal ... Book Review: Origins of Phobias and Anxiety Disorders: Why More ...

  3. Relationship between Tobacco Advertising and Youth Smoking: Assessing the Effectiveness of a School-Based Antismoking Intervention Program.

    Science.gov (United States)

    Beltramini, Richard F.; Bridge, Patrick D.

    2001-01-01

    The Hazards of Tobacco (C) program, which focuses on smoking prevention among youth, was completed by 259 suburban sixth graders (199 controls) and 166 urban fifth through seventh graders. Participation significantly changed understanding of the role of tobacco advertising and the intention to smoke in both samples. (Contains 49 references.) (SK)

  4. Neural Stem Cell Delivery of Therapeutic Antibodies to Treat Breast Cancer Brain Metastases

    Science.gov (United States)

    2009-10-01

    and Engineering Neural Stem Cells for Delivery of Genetically Encoded 259 References 1. Snyder, EY., Deichter, DL., Walsh, C., Arnold- Aldea , S...acquired with a Zeiss Axio Imager M1m microscope equipped with a digital camera, using 10x or 20x air objectives. Digital images were analyzed using

  5. Domain Modeling: NP_037512.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_037512.3 chr19 Aart, a six finger zinc finger designed to recognize ANN triplets... c2i13b_ chr19/NP_037512.3/NP_037512.3_holo_250-425.pdb blast 257Y,259K,261F,262S,264D,265S,266S,268E,270H,2

  6. Sleepless in Chicago: Tracking the Effects of Adolescent Sleep Loss During the Middle School Years

    Science.gov (United States)

    Fredriksen, Katia; Rhodes, Jean; Reddy, Ranjini; Way, Niobe

    2004-01-01

    The influence of the sleep patterns of 2,259 students, aged 11 to 14 years, on trajectories of depressive symptoms, self-esteem, and grades was longitudinally examined using latent growth cross-domain models. Consistent with previous research, sleep decreased over time. Students who obtained less sleep in sixth grade exhibited lower initial…

  7. Identification of Species Related to Anopheles (Nyssorhynchus) albitarsis by Random Amplified Polymorphic DNA-Polymerase Chain Reaction (Diptera: Culicidae)

    Science.gov (United States)

    1995-11-01

    of dif- ferences between whiteflies using RAPD-PCR. Insect Mol Biol2: 33-38. Hadrys H, Balick M, Schierwater B 1992. Apphca- tions of random...Bellows TS 1993. Identification of a whitefly spe- cies by genomic and behavioral studies. Science 259: 74-77. Peyton EL, Wilkerson RC, Harbach RE

  8. Data of evolutionary structure change: 1BWMA-2NTSP [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1BWMA-2NTSP 1BWM 2NTS A P AVTQSPRNKVAVTGGKVTLSCNQTNNHNNMYWYRQDTGH...LY CA 452 ARG CA 529 ALA CA 544 GLU CA 635 2NTS P 2NTSP CASSL...> LYS CA 357 ARG CA 259 2NTS P 2NTSP NGKEVHSGVSTD

  9. Brown bear surveys of Becharof National Wildlife Monument, summer of 1980

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — A total of 347 bears were classified (Table I). The composition of the population surveyed was 90 cubs (25.9 %), 155 yearlings (15.9 %), 178 sows with young (22.5...

  10. Distinguishing Complicated from Uncomplicated Bacteremia Caused by Staphylococcus aureus: The Value of "New" and "Old" Serological Tests

    NARCIS (Netherlands)

    H.A. Verbrugh (Henri); W.H.F. Goessens (Wil); M.F. Michel; R. Peters (Roel)

    1986-01-01

    textabstractAntibody responses to staphylococcal α-toxin, cell wall teichoic acid, and cell wall peptodoglycan were measured in 259 serum samples from 74 consecutive patients with Staphylococcus aureus bacteremia. All patients with complicated bacteremia were seropositive in at least one of three

  11. An Annotated Bibliography of Literature Integrating Organizational and Systems Theory

    Science.gov (United States)

    1985-09-01

    discussed. The remainder of the book is devoted to dis- cussions of relationships between selected organizational characteris- tics and organizational...irrationality, it is suggested, can be replaced by the behavioral notions of error and 4L. ignorance. -259- V,% coodmran, . . King, D. C. Organizacional

  12. Kinetic speciation of mercury–humate complexes in aqueous solutions by using competing ligand exchange method

    Digital Repository Service at National Institute of Oceanography (India)

    Vudamala, K.; Chakraborty, P.

    river emptying into Cochin backwaters, Indian J. Mar. Sci. 15 (1986) 253–259. http://cat.inist.fr/?aModele=afficheN&cpsidt=8219806 (accessed September 4, 2015). [25] P.K. Krishnakumar, V.K. Pillai, Mercury Near a Caustic Soda plant at karwar,India, Mar...

  13. ADHD Medication Vacations and Parent-Child Interactions by Gender

    Science.gov (United States)

    Barnard-Brak, Lucy; Schmidt, Marcelo; Sulak, Tracey

    2013-01-01

    Objective: The purpose of the current study was to examine medication vacations among children with ADHD according to parent-child dyads (e.g., mother-son, father-daughter, mother-daughter, and father-son). Method: In a survey study of 259 parents of children with ADHD, the use of medication vacations according to parent-child sex dyads was…

  14. Production of secreted guar α-galactosidase by Lactococcus lactis

    NARCIS (Netherlands)

    Leenhouts, K.J.; Bolhuis, A.; Ledeboer, A.; Venema, G.; Kok, J.

    1995-01-01

    A plant α-galactosidase gene was inserted in the expression vector pGKV259. The resulting plasmid pGAL2 consisted of the replication functions of the broad-host-range lactococcal plasmid pWV01, the lactococcal promoter P59, and the DNA sequences encoding the α-amylase signal sequence from Bacillus

  15. Production of secreted guar alpha-galactosidase by Lactococcus lactis

    NARCIS (Netherlands)

    Leenhouts, KJ; Bolhuis, A; Ledeboer, A; Venema, G; Kok, J

    1995-01-01

    A plant alpha-galactosidase gene was inserted in the expression vector pGKV259. The resulting plasmid pGAL2 consisted of the replication functions of the broad-host-range lactococcal plasmid pWVO1, the lactococcal promoter P59, and the DNA sequences encoding the alpha-amylase signal sequence from

  16. Galaxy number counts and implications for strong lensing

    NARCIS (Netherlands)

    Fassnacht, C. D.; Koopmans, L. V. E.; Wong, K. C.

    2011-01-01

    We compare galaxy number counts in Advanced Camera for Surveys (ACS) fields containing moderate-redshift (0.2 259 ACS fields and (2) 20 ‘pure-parallel’ fields randomly

  17. Ranking of Prophylactic Efficacy of Poly(ICLC) against Rift Valley Fever Virus Infection in Mice by Incremental Relative Risk of Death

    Science.gov (United States)

    1987-08-01

    days by stimulation of the immune response (2. 14) and with 0.1 ml (250 PFU) of virus. induction of interferon production (7. 8). Interferon and the...mice of polyinos~lnic-polycytidylic 259. acid complexed with poly-L-lysine and carboxymethylcellulose . 9. Levy. H. B., and F. L. Riley. 1983. A

  18. The Effects of Changes in Racial Identity and Self-Esteem on Changes in African American Adolescents' Mental Health

    Science.gov (United States)

    Mandara, Jelani; Gaylord-Harden, Noni K.; Richards, Maryse H.; Ragsdale, Brian L.

    2009-01-01

    This study assessed the unique effects of racial identity and self-esteem on 259 African American adolescents' depressive and anxiety symptoms as they transitioned from the 7th to 8th grades (ages 12-14). Racial identity and self-esteem were strongly correlated with each other for males but not for females. For both males and females, an increase…

  19. Social Desirability as a Predictor of Argumentativeness, Communication Apprehension, and Communication Competence.

    Science.gov (United States)

    Chen, Guo-Ming

    A study investigated the relationships between social desirability (the tendency to seek socially and culturally approved behaviors) and argumentativeness, communication apprehension, and communication competence. Using R. Strahan and K. C. Gerbasi's Social Desirability Scales, from a pool of 259 undergraduate students, 70 students were identified…

  20. Wages and Productivity in Mexican Manufacturing. Policy Research Working Paper.

    Science.gov (United States)

    Lopez-Acevedo, Gladys

    A study examined determinants of wages and productivity in Mexico from 1993 and 1999 using two national surveys. In 1993, 7,619 employees from 575 firms were interviewed. In 1999, 6,259 employees from 722 firms were interviewed. Findings indicate that wage premiums and productivity increased with years of schooling, but workers had higher benefits…

  1. Are Chileans exposed to dietary furan?

    DEFF Research Database (Denmark)

    Mariotti, Maria; Toledo, Carla; Hevia, Karen

    2013-01-01

    ) and low moisture starchy products like crisps and “soda”-type crackers showed the highest furan concentrations (259 and 91 ng g−1, respectively). Furthermore, furan was also found in samples of breakfast cereals (approximately 20 ng g−1), jarred fruit baby foods (8.5 ng g−1) and orange juice (7.0 ng g−1...

  2. Noninvasive Spatially Offset and Transmission Raman Mapping of Breast Tissue: A Multimodal Approach Towards the In Vivo Assessment of Tissue Pathology

    Science.gov (United States)

    2013-06-01

    Appl. Phys. Lett. 2003, 82, 257−259. (13) Alvarez- Puebla , R. A. Effects of the Excitation Wavelength on the SERS Spectrum. J. Phys. Chem. Lett. 2012...Pieczonka, N. P. W.; Aroca, R. F. Single Molecule Analysis by Surfaced-Enhanced Raman Scattering. Chem. Soc. Rev. 2008, 37, 946− 954. (7) Alvarez- Puebla , R

  3. 77 FR 54947 - Unblocking of Specially Designated Nationals and Blocked Persons Pursuant to the Foreign...

    Science.gov (United States)

    2012-09-06

    ... CRIADERO LAS CABANAS LTDA., Bogota, Colombia; Calle 137 No. 52-37, Rincon Iberia, Bogota, Colombia; San... Jardin Balbuena, Delegacion Venustiano Carranza, Mexico City, Distrito Federal, Mexico; Martin Luis... Venustiano Carranza, Mexico City, Distrito Federal, Mexico; Martin Luis Guzman No. 259, Colonia Villa...

  4. Stress among Secondary School Teachers in Ebonyi State, Nigeria: Suggested Interventions in the Worksite Milieu

    Science.gov (United States)

    Nwimo, Ignatius O.; Onwunaka, Chinagorom

    2015-01-01

    The aim of the study was to determine the level of stress experienced by secondary school teachers in Ebonyi State. The dimensions of stress studied included physical stress, mental stress, emotional stress and social stress. The study adopted the cross-sectional survey design using a sample of 660 (male 259, female 401) teachers randomly drawn…

  5. Data of evolutionary structure change: 1GADO-3CIFB [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1GADO-3CIFB 1GAD 3CIF O B TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLL-DAD...ine> ASP CA 257 TYR CA 259 MET CA 367 3CIF... B 3CIFB ...ine> ILE CA 419 VAL CA 453 SER CA 509 3CIF... B 3CIFB TEYDPSKFNVIS

  6. Data of evolutionary structure change: 1GADO-3CIFD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1GADO-3CIFD 1GAD 3CIF O D TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLL-DAD...ine> ASP CA 257 TYR CA 259 MET CA 367 3CIF... D 3CIFD ...n> 3CIF D 3CIFD NTEY...01 TRP CA 190 ARG CA 258 GLY CA 288 3CIF

  7. Data of evolutionary structure change: 1GAEO-3CIFD [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1GAEO-3CIFD 1GAE 3CIF O D TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLL-DAD...17 ASP CA 257 TYR CA 254 MET CA 368 3CIF... D 3CIFD 3CIF D 3CIFD ...YS CA 137 ASP CA 200 TRP CA 189 ARG CA 259

  8. Data of evolutionary structure change: 1GAEO-3CIFA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1GAEO-3CIFA 1GAE 3CIF O A TIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDL-LDAD...P CA 250 ALA CA 317 ASP CA 257 TYR CA 254 3CIF... A 3CIFA 3CIF A 3CIFA NTEY...ne> ASP CA 200 TRP CA 189 ARG CA 259 3CIF

  9. Myocardial scintigraphy. Clinical use and consequence in a non-invasive cardiological department

    DEFF Research Database (Denmark)

    Dümcke, Christine Elisabeth; Graff, J; Rasmussen, SPL

    2006-01-01

    to analyse the clinical use of MPI in a university hospital without invasive cardiological laboratory. MATERIAL AND METHODS: In the period 01.01.2002 to 31.12.2003, 259 patients (141 women, 118 men) were referred to MPI from our department of cardiology. RESULTS: Normal MPI was seen in 111 patients (43...

  10. Examining the Relationship between Teacher Leadership and School Climate

    Science.gov (United States)

    Kilinc, Ali Çagatay

    2014-01-01

    Teacher leadership has recently become the centre of educational research on improving educational practices. The purpose of this study was to examine the relationships between primary school teachers' perceptions of school climate and teacher leadership. The study sample consisted of 259 primary school teachers who participated in an…

  11. Developing cDNA Libraries of Receptors Involved in the Recruitment of the Biofouling Tubeworm Hydroides elegans

    Science.gov (United States)

    2014-06-12

    protein complex that controls the transcription of DNA (transcription factor) in response to stimuli such as stress and/or viral or bacterial...Plasmids (14) Membrane Transport (148) Iron acquisibon and metabolism (37) RNA Metabolism (186) Nudeosides and Nucleotides (88) Protein... Carbohydrates (259) Figure 2: RAST analysis of Pseudoalteromonas luteoviolacea Subsystem Category Distribution Subsystem Feature Counts Cofactors, Vitamins

  12. Success Factors in New Ventures: A Meta-analysis

    NARCIS (Netherlands)

    Song, Michael; Podoynitsyna, Ksenia; Bijl, van der Hans; Halman, Johannes I.M.

    2008-01-01

    Technology entrepreneurship is key to economic development. New technology ventures (NTVs) can have positive effects on employment and could rejuvenate industries with disruptive technologies. However, NTVs have a limited survival rate. In our most recent empirical study of 11,259 NTVs established b

  13. 77 FR 16091 - Order Modifying Licenses With Regard to Requirements for Mitigation Strategies for Beyond-Design...

    Science.gov (United States)

    2012-03-19

    ..., and Title 10 of the Code of Federal Regulations (10 CFR) Part 50, ``Domestic Licensing of Production... Authority, Docket Nos. 50-259, 50-260 and 50-296, License Nos. DPR-33, DPR-52 and DPR-68 Mr. Preston D... Operating Company, Inc., Edwin I. Hatch Nuclear Plant, 11028 Hatch Parkway North, Baxley, GA 31513 Fermi...

  14. Extraction and Configuration of an Isolate from Chrysanthellum ...

    African Journals Online (AJOL)

    MBI

    2014-09-23

    Sep 23, 2014 ... 1Department of chemistry, Federal University Dutse. 2Department of Pure and ... to the isolation of a white chrystaline compound which melted at a temperature range of (257-259°C) with .... Mutagenicity of Cigarette Smoke.

  15. Productivity convergence across industries and countries : The importance of theory-based measurement

    NARCIS (Netherlands)

    Inklaar, R.; Timmer, M.P.

    Cross-country studies of economic growth have been hampered by the scarcity of reliable data on productivity at the industry level; see Bernard and Jones [American Economic Review, 91 (4) (2001) 1168-1169] and Rogerson [Journal of Political Economy, 116 (2) (2008), 235-259]. We bring together

  16. Magnetic-Field-Assisted Assembly of Ordered Multifunctional Ceramic Nanocomposites for Extreme Environments

    Science.gov (United States)

    2016-04-01

    processing mullite films, poly( ethylene oxide ) (or PEO), polyvinyl alcohol (or PVA) and polyvinylpyrrolidone (or PVP) were added in the precursor to... Synthesis and characterization of nickel nanoparticles by hydrazine reduction in ethylene glycol. Journal of Colloid and Interface Science 259, 282...Specific tasks ........................................................................................................................... 4 1.1 Synthesis

  17. The Predictive Value of Selected Extrinsic and Intrinsic Indicators of Overall Job Satisfaction in Diagnostic Radiological Technology, Radiation Therapy, and Nuclear Medicine Technology Allied Health Faculty

    Science.gov (United States)

    Beavers, Gregory S.

    2010-01-01

    Healthcare is the largest industry in the United States and 60 percent of its 14 million workers are in allied health jobs. The need to attract and retain allied health faculty is critical to preparing a competent workforce in healthcare. This study reports the results of a survey of 259 faculty members working in diagnostic radiologic technology,…

  18. Identification of two novel nodule-specific genes from Astragalus sinicus L. by suppressive subtractive hybridization

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    To identify the genes involved in nodule formation and to increase usable molecular probes, a cDNA library of Astragalus sinicus genes specifically expressed in infected roots by Mesorhizobium huakuii 7653R is generated using a PCR-based suppressive subtractive hybridization (SSH) technique with two mRNA populations of infected and uninfected control roots. Two nodule-specific genes, AsIIC259 and AsG2511, are identified from infected roots of A. sinicus. The amino acid sequences deduced from the open reading frames (ORFs) reveal that AsIIC259 and AsG2511 encodes a polypeptide with 134 and 58 amino acids, respectively. A signal peptide sequence is predicted with high probability at the N-termini of the AsIIC259 and AsG2511. The motif searches show that the deduced polypeptide of AsIIC259 contains two N-glycosylation sites, a cAMP- and cGMP-dependent protein kinase phosphorylation site and a casein kinase II phosphorylation site. BLASTP searches reveal that AsIIC259 putative protein displays a low degree of similarity to a unique nodulin from Lupinus luteus nodules. No significant identity is displayed over the predicted polypeptides of AsG2511 with any published sequences. Virtual Northern blot and semi-quantitative reverse transcription-polymerase chain reaction (RT-PCR) analyses indicate that the two genes are expressed exclusively in inoculated roots and that their expression is 2-4 d later than that of the leghaemoglobin (Lb) gene during nodule development.

  19. Revisão de literatura em enfermagem sobre hipertensão arterial na gravidez Revision de la literatura en enfermería sobre la hipertensión arterial en el embarazo Nursing literature review on pregnancy induced hypertension

    Directory of Open Access Journals (Sweden)

    Sonia Maria Junqueira V de Oliveira

    2001-09-01

    Full Text Available Revisão de literatura em enfermagem relativa à hipertensão arterial na gravidez, entre 1980 a 1999, com o objetivo de identificar as tendências dessas publicações. Foram encontradas 58 publicações nos idiomas inglês, português e espanhol, sendo 52 artigos de periódicos e 6 monografias, dissertações e teses. A maioria dos artigos foi publicada em periódicos de enfermagem (84,6%, predominando os de língua inglesa (73,1%, redigidos por docentes, com autoria única. Predominaram os enfoques assistência de enfermagem (25,9% e tratamento medicamentoso (25,9%. A partir de 1985, observou-se um incremento nas publicações, no entanto, ainda são incipientes as publicações nacionais.Revisión de la literatura en enfermería, relativa a la hipertensión arterial en el embarazo, entre 1980 y 1999, con el objetivo de identificar las tendencias de esas publicaciones. Fueron encontradas 58 publicaciones en los idiomas ingles, portugués y español, siendo 52 artículos de periódicos y 6 monografias y tesis. La mayoría de los artículos fue publicada en periódicos de enfermería (84,6%, predominando los de lengua inglesa (73,1%, redactados por docentes, con autoria única. Predominaron los enfoques de la atención en enfermería (25,9% y tratamiento medicamentoso (25,9%. Se observó un incremento en las publicaciones a partir de 1985, más las publicaciones nacionales sobre la hipertensión arterial en el embarazo son aún incipientes.Nursing literature review, related to pregnancy induced hypertension, from 1980 to 1999, with the objective of identifying the tendencies of those publications. 58 publications were found in the English, Portuguese and Spanish languages, being 52 articles from periodicals and 6 monographs, dissertations and thesis. Most of the articles was published in nursing periodicals (84,6%, prevailing the English ones (73,1%, written by academicians, with sole writing. The focuses nursing care (25,9% and pharmacological

  20. Developments for transactinide chemistry experiments behind the gas-filled separator TASCA

    Energy Technology Data Exchange (ETDEWEB)

    Even, Julia

    2011-12-13

    synthesised carbonyl complexes were identified by nuclear decay spectroscopy. Some complexes were studied with isothermal chromatography or thermochromatography methods. The chromatograms were compared with Monte Carlo Simulations to determine the adsorption enthalpyrnon silicon dioxide and on gold. These simulations based on existing codes, that were modified for the different geometries of the chromatography channels. All observed adsorption enthalpies (on silcon oxide as well as on gold) are typical for physisorption. Additionally, the thermalstability of some of the carbonyl complexes was studied. This showed that at temperatures above 200 C therncomplexes start to decompose. It was demonstrated that carbonyl-complex chemistry is a suitable method to study rutherfordium, dubnium, seaborgium, bohrium, hassium, and meitnerium. Until now, only very simple, thermally stable compounds have been synthesized in the gas-phase chemistry of the transactindes. With the synthesis of transactinide-carbonyl complexes a new compound class would be discovered. Transactinide chemistry would reach the border between inorganic and metallorganic chemistry. Furthermore, the in-situ synthesised carbonyl complexes would allow nuclear spectroscopy studies under low background conditions making use of chemically prepared samples. [German] Die vorliegende Arbeit befasst sich mit der Entwicklung von Experimenten hinter dem gasgefuellten Separator TASCA (TransActinide Separator and Chemistry Apparatus) zur Studie des chemischen Verhaltens der Transactinide. Zum einen wurde die Moeglichkeit der elektrochemischen Abscheidung kurzlebiger Isotope der Elemente Ruthenium und Osmium auf Goldelektroden im Hinblick auf ein Experiment mit Hassium untersucht. Aus der Literatur ist bekannt, dass bei der elektrochemischen Abscheidung einzelner Atome das Abscheidepotential signifikant vom Nernst-Potential abweicht. Die Verschiebung des Potentials haengt von der Adsorptionsenthalpie des abzuscheidenden Elements

  1. Estructura y funcionamiento de un servicio de cirugía mayor ambulatoria y de corta hospitalización

    Directory of Open Access Journals (Sweden)

    Juan Carlos Domínguez Lanuza

    1999-04-01

    Full Text Available Se realizó estudio de la estructura y funcionamiento del Servicio de Cirugía Ambulatoria y de Corta Hospitalización del Hospital Clinicoquirúrgico Docente "Miguel Enríquez", desde su creación en abril de 1989 hasta diciembre de 1995, donde se analizaron el total de intervenciones mayores (12 259 por las diferentes especialidades quirúrgicas, así como el organigrama de trabajo, y se constató un bajo índice de complicaciones (4,7 %A study of the structure and functioning of the Service of Ambulatory Surgery and of Short Hospitalization of the "Miguel Enríquez" Clinical and Surgical Teaching Hospital since its creation in April, 1989, to December, 1995, was conducted. The total amount of major procedures (12 259 by different surgical specialities and the working flowchart were analyzed. A low index of complications (4.7 % was obtained

  2. Prevalence and etiology of nosocomial diarrhoea in children hospital.

    Science.gov (United States)

    Alrifai, S B; Alsaadi, A; Mahmood, Y A; Ali, A A; Al-Kaisi, L A

    2009-01-01

    A cross-sectional hospital-based study was carried out at Tikrit teaching hospital, Iraq, from October 2004 to September 2005, to identify the prevalence and etiology of nosocomial infectious diarrhoea among children under 5 years of age. Of 259 children admitted to the paediatric ward for reasons other than diarrhoea and hospitalized for more than 3 days, clinical and laboratory analysis of stool samples showed nosocomial diarrhoea in 84 children (32.4%). The most common causative agents were enteropathogenic Escherichia coli (25.9%), Clostridium difficile (21.0%) and rotavirus (18.5%). Single infectious agents caused 63.1% of the cases, while mixed infections were detected in 16.7%; in 20.2% of children the cause remained unknown.

  3. The Role of BRCA1 in Lethal Prostate Cancer

    Science.gov (United States)

    2013-08-01

    c 3 + 4 198 (37.4) 17 (28.3) 4 + 3 137 (25.9) 20 (33.3) ≥ 8 100 (18.9) 17 (28.3) Pathologic TNM stage e , n (%) pT2 342 (68.7) 35 (72.9) 0.34 c pT3...correlation between BRCA1 expression and pathologic TNM stage was found. Compared to BRCA1-negative tumors, tumors expressing BRCA1 exhibited a...Gleason score, n (%) ≤ 6 94 (17.8) 6 (10.0) 0.01c 3 + 4 198 (37.4) 17 (28.3) 4 + 3 137 (25.9) 20 (33.3) ≥ 8 100 (18.9) 17 (28.3) Pathologic TNM stage

  4. Thoracic spinal trauma associated with closed thoraco-abdominal injury

    Institute of Scientific and Technical Information of China (English)

    路磊; 吴立文; 范广宇

    2003-01-01

    Objective: To explore the management of thoracic spinal trauma (TST) associated with closed thoraco-abdominal injuries (CTAI). Methods: A retrospective study was made on 259 patients with TST admitted to our department as an emergency treatment from January 1996 to June 2001. We summarized the clinical features of TST associated with CTAI. Results: Among 259 patients with thoracic spinal trauma, 112 were associated with CTAI. Traffic accident was the most common cause. The force causing upper TST was more violent than that causing the lower. Pulmonary complications were the leading cause of death in this group. Surgery could not improve neurological function for completely paraplegic patients.Conclusions: The reason that upper TST has the tendency to be associated with CTAI is its special anatomical feature. Routine ultrasonic examination can avoid misdiagnosis of latent closed abdominal injuries associated with spinal injury. The presence of potential injuries, especially CTAI, should be considered when deciding whether or not to perform surgery early.

  5. ERG and VEP in predicting postoperative vision of cataract patients%ERG及VEP对白内障術後视力的预測

    Institute of Scientific and Technical Information of China (English)

    王升; 郭潔; 王引俠

    2002-01-01

    目的探討ERG及VEP封白内障術後视力的预測作用.方法應用ERG及VEP封259祗白内障眼進行檢查并舆術後視力進行分析.結果259祗眼中VEP表现爲潜伏期延長66眼,P1OO及N75振幅降低73祗眼,正常183祗眼,ERG潜伏期延遲66眼,振幅降低67眼.結論VEP及ERG潜伏期延遲,振幅降低,術後視力差,它們能較好的预測白内障的術後視力.

  6. ERG及VEP对白内障术后视力的预测

    Institute of Scientific and Technical Information of China (English)

    王升; 郭洁; 等

    2002-01-01

    目的:探讨ERG及VEP对白内障术后视力的预测作用。方法:应用ERG及VEP对259只白内障眼进行检查并与术后视力进行分析,结果:259只眼中VEP表现为潜伏期延长66眼,P100及N75振幅降低73只眼,正常183只眼,ERG潜伏期管迟66眼,振幅降低67眼,结论:VEP及ERG潜伏期延迟,振幅降低,术后视力差,它们能较好的预测白内障的术后视力。

  7. Human platelet specical antigen-17bw (HPA-17bw) genotyping and genetic frequency study%血小板特异性抗原HPA-17bw基因分型及基因频率调查

    Institute of Scientific and Technical Information of China (English)

    刘衍春; 薛敏; 吴敏慧; 许剑锋; 唐荣才

    2009-01-01

    目的 对HPA-17bw基因分型并调查其在部分汉族人群中的分布.方法 采用PCR-SSP方法 对无亲缘关系的健康无偿献血者HPA-17bw进行基因分型,采用基因计数法进行基因频率、基因型频率的计算.结果 259名正常人的HPA-17bw基因频率为0.000; HPA-17 bw/bw的基因型频率为0.000.结论 HPA-17bw为低频抗原,259份汉族样本中尚检测不出HPA-17bw.

  8. Amino Acids in Nectar Enhance Longevity of Female Culex quinquefasciatus

    Science.gov (United States)

    2010-01-01

    Culicidae) fed aqueous extracts of pollen. Annals of the Entomological Society of America 76, 661–663. Foster,W.A., 1995.Mosquito feeding and reproductive...different diets. Annals of the Entomological Society of America 53, 277–280. Martin, O.Y., Hosken, D.A., 2004. Copulation reduces male but not female...Verbenaceae]), Notorious weed and popular garden flower; some cases of poisoning in Florida. Economic Botany 48, 259–270. Nasci, R.S., 1991. Influence of

  9. Characterization of HIV Transmission in South-East Austria.

    Directory of Open Access Journals (Sweden)

    Martin Hoenigl

    Full Text Available To gain deeper insight into the epidemiology of HIV-1 transmission in South-East Austria we performed a retrospective analysis of 259 HIV-1 partial pol sequences obtained from unique individuals newly diagnosed with HIV infection in South-East Austria from 2008 through 2014. After quality filtering, putative transmission linkages were inferred when two sequences were ≤1.5% genetically different. Multiple linkages were resolved into putative transmission clusters. Further phylogenetic analyses were performed using BEAST v1.8.1. Finally, we investigated putative links between the 259 sequences from South-East Austria and all publicly available HIV polymerase sequences in the Los Alamos National Laboratory HIV sequence database. We found that 45.6% (118/259 of the sampled sequences were genetically linked with at least one other sequence from South-East Austria forming putative transmission clusters. Clustering individuals were more likely to be men who have sex with men (MSM; p<0.001, infected with subtype B (p<0.001 or subtype F (p = 0.02. Among clustered males who reported only heterosexual (HSX sex as an HIV risk, 47% clustered closely with MSM (either as pairs or within larger MSM clusters. One hundred and seven of the 259 sequences (41.3% from South-East Austria had at least one putative inferred linkage with sequences from a total of 69 other countries. In conclusion, analysis of HIV-1 sequences from newly diagnosed individuals residing in South-East Austria revealed a high degree of national and international clustering mainly within MSM. Interestingly, we found that a high number of heterosexual males clustered within MSM networks, suggesting either linkage between risk groups or misrepresentation of sexual risk behaviors by subjects.

  10. High-Throughput Sequencing of Germline and Tumor From Men with Early-Onset Metastatic Prostate Cancer

    Science.gov (United States)

    2016-12-01

    specimens as initially proposed. Concurrently, Dr. Tomlins developed state of the art technologies to use FFPE prostate cancer specimens for molecular...capture based NGS and qPCR approaches, and multiplexed PCR NGS based approaches. Therefore, we modified our approach to use archived FFPE biopsy and...tissue, we had the opportunity to molecularly profile both the initial prostate cancer (PR-259, DOD_03a) and the liver biopsy which contained

  11. Clarifying Boundaries of Binge Eating Disorder and Psychiatric Comorbidity: A Latent Structure Analysis

    OpenAIRE

    Hilbert, Anja; Denise E. Wilfley; Dohm, Faith-Anne; Pike, Kathleen M; Fairburn, Christopher G.; Striegel-Moore, Ruth H.

    2010-01-01

    Binge eating disorder (BED) presents with substantial psychiatric comorbidity. This latent structure analysis sought to delineate boundaries of BED given its comorbidity with affective and anxiety disorders. A population-based sample of 151 women with BED, 102 women with affective or anxiety disorders, and 259 women without psychiatric disorders was assessed with clinical interviews and self-report questionnaires. Taxometric analyses were conducted using DSM-IV criteria of BED and of affectiv...

  12. Kidney function

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    2010356 Association of risk factors for cardiovascular disease and the rate of glomerular filtration:a cross-sectional study in the population from certain areas of Beijing. WANG Fan(王凡),et al.Dept Geriat Cardiol,Chin PLA General Hosp,Beijing 100853.Chin J Epidemiol 2010;31(3):256-259. Objective To explore the correlation between risks factors of cardiovascular

  13. Space Storms and Space Weather Hazards

    Science.gov (United States)

    2007-11-02

    work has been supported by the Research Contract BL/10/B07 from the Belgian “Services Fédéraux des Affaires Scientifiques, Techniques et Culturelles ...Ionospshere Solar Wind Earth Sun Magnetosphere X Z Figure 1. Schematic of the Sun and geospace. Plasma coupling between the Sun and Earth, mediated by the...Rev., 94, 259-278. Yu, F. and Turco, R. (2000) Ultrafine aerosol formation via ion- mediated nucleation, Geophys. Res. Lett. 27, 883-886. Chapter 10

  14. Office of Naval Research Graduate Fellowship Program

    Science.gov (United States)

    1994-07-29

    II Biological/Bioredical Sciences - Dupont I Carolyn Cousin, University of the District of Columbia Vito DelVecchio, University of Scranton Richard...performance semiconductor devices. Penetration-resistant alloys. Ms. Alice Man 259 Saint Paul Street Brookline, MA 02146 617-734-9211 MIT Materials science...than research experience. Her referees also described her potential rather than research involvement. Sylvia Howard had a 3.48 from Saint Paul’s

  15. Genetic diversity of Mycobacterium tuberculosis isolates from foreign-born and Japan-born residents in Tokyo.

    Science.gov (United States)

    Kato-Miyazawa, M; Miyoshi-Akiyama, T; Kanno, Y; Takasaki, J; Kirikae, T; Kobayashi, N

    2015-03-01

    Sequences of the full genomes of 259 clinical isolates of Mycobacterium tuberculosis, obtained from foreign-born and Japan-born patients in Tokyo, Japan, were determined, and a phylogenetic tree constructed by concatenated single-nucleotide polymorphism (SNP) sequences. The 259 isolates were clustered into four clades: Lineage 2 (East Asian or "Beijing" genotype; n = 182, 70.3%), Lineage 4 (Euro-American, n = 46, 17.8%), Lineage 1 (Indo-Oceanic, n = 23, 8.9%), and Lineage 3 (East African-Indian, n = 8, 3.1%). Of the 259, 36 (13.9%) were resistant to at least one drug. There was no multi-drug-resistant isolate. Drug resistance was greater for the strains in Lineage 2 than the non-Lineage 2. The proportion of Lineage 2 isolates was significantly smaller in foreign-born (n = 43/91, 47.3%) than in Japan-born (n = 139/168, 82.7%) patients, whereas the proportion of Lineage 1 isolates was significantly larger in foreign-born (n = 19/91, 20.9%) than in Japan-born (n = 4/168, 2.4%) patients. We also found eight SNPs specific to the typical Beijing sub-genotype in Lineage 2, including 4 non-synonymous SNPs. Of the 259 isolates, 244 had strain-specific SNP(s) and small (1-30-bp) insertions and deletions (indels). The numbers of strain-specific SNPs and indels per isolate were significantly larger from foreign-born (median 89, range 0-520) than from Japan-born (median 23, range 0-415) (p 3.66E-15) patients. These results suggested that M. tuberculosis isolates from foreign-born patients had more genetic diversity than those from Japan-born patients.

  16. Inserting Agility in System Development

    Science.gov (United States)

    2012-07-01

    Agile IT Acquisition, IT Box, Scrum Inserting Agility in System Development Matthew R. Kennedy and Lt Col Dan Ward, USAF With the fast-paced nature...1,700 individuals and 71 countries, found Scrum and eXtreme Programming to be the most widely followed method- ologies (VersionOne, 2007). Other...University http://www.dau.mil 259 Defense ARJ, July 2012, Vol. 19 No. 3 : 249–264 Scrum Scrum is a framework used for project management, which is

  17. The Evaluation of Post-Exposure Prophylaxis Models for Use in the Event of an Aerosolized Anthrax Attack

    Science.gov (United States)

    2014-09-01

    providing a 10-day antibacterial drug supply for first responders to keep in their homes. The letter listed three oral antibacterial drugs...Equivalent Professional.” 167 Clare Stroud et al., “Commissioned Paper : A Cost and Speed Analysis of Strategies,” National Center for Biotechnology...would reduce the burden on those 170 Stroud et al., ed., Prepositioning Antibiotics for Anthrax, 257–259. 171 Stroud et al., “Commissioned Paper : A

  18. East Europe Report, Economic and Industrial Affairs.

    Science.gov (United States)

    2007-11-02

    machinery for sugar beet cultivation and har- vesting in 1982 and of 55 units in 1983 satisfied the demand for the time being. Last year our beet growers...also acquired 259 3-row diggers, 235 SC-031 self- propelled beet toppers and 141 KS 6B self-propelled harvesters. Last year our agricultural...the state was replaced by one which bore within itself elements of market economy. We also introduced suitable new agrarian policies, which, with a

  19. The Economic Cost of Methamphetamine Use in the United States, 2005

    Science.gov (United States)

    2009-01-01

    Department of Defense xviii The Economic Cost of Methamphetamine Use in the United States, 2005 DSM-IV Diagnostic and Statistical Manual for Mental...so we turn to the NSDUH. Each year, the NSDUH reports the number of people meeting Diagnostic and Statistical Manual for Mental Disorders (DSM-IV...Acta Obstetricia et Gynecologica Scandinavica, Vol. 60, No. 3, 1981, pp. 253–259. Eriksson, M., and R. Zetterström, “Amphetamine Addiction During

  20. Why Some People Live and Some People Die in the Same Emergencies and Disasters: Can the General Public Be Taught to Save Themselves?

    Science.gov (United States)

    2013-03-01

    actually be slowing down the decision-making process. Klein (1999) refers to this as “analysis by paralysis ” (p. 259). Newer employees may need to follow...evacuate. Figure 6 shows the leading activities during fire fatalities ( sleeping and escaping) and compares them with the age groups of those killed...slightly more victims in residential structure fires (35.9%) died attempting to escape while slightly less (34.3%) died in their sleep (see Figure 8). With

  1. Bibliography of Ice Properties and Forecasting Related to Transportation in Ice-Covered Waters.

    Science.gov (United States)

    1980-09-01

    tests, usually reacted suits are given for tests made in uniaxial tension and more strongly in tension than the course -grained uniaxial compression at... course of development over various time scales; 1967, 35 pp. 5) identification of the effects of volcanic (and other The ice program conducted by the...September 1966. 259 pp. satellite. Journal at Geophysical Research. Vol. 78. The Spacecraft Oceanography Project ( SPOC ) No. 9, 20 March 1973. pp 1427-1448

  2. Frequency of human toxocariasis in Jos, Plateau State, Nigeria

    Directory of Open Access Journals (Sweden)

    OO Ajayi

    2000-04-01

    Full Text Available The enzyme-linked immunosorbent assay (Elisa was used to examine sera of 104 children and adults in Jos, Plateau State, Nigeria for anti-toxocaral antibodies, out of which 31 (29.8% were reactive. The seropositive rates were 30.4% for adults, 29.6% for children, 34% for females and 25.9% for males. However, the differences were not significant by age and sex. A highly significant association (p 0.05.

  3. Annual Research Progress Report, FY 1991

    Science.gov (United States)

    1991-09-30

    Powder. Ann Allergy 66:301-304, 1991. Larsen LV, Copeland TA, Weber RW, Vaughan TR: Allergen Extraction Methods: Effects of Time, Temperature, Buffer...Subretinal Hemorrhage: A Case Report. Ann Ophthalmol 22:259-262, 1990. Weston B, Enzenauer RW, Kraft SP, Gayowky GR: Stability of the Postoperative Alignment...Teresa Copeland , CPT, MC (11) Key Words: David L. Goodman, LTC, MC migraine food hypersensitivity mediators (12) Accumulative MEDCASE:* (13) Est Accum OMA

  4. AcEST: DK955655 [AcEST

    Lifescience Database Archive (English)

    Full Text Available in OS=Betula verrucosa PE=2 SV=1 259 4e-68 tr|A9QVH4|A9QVH4_9CONI Alpha tubulin OS=Picea wilsonii GN=TUA1 P....A9QVH4|A9QVH4_9CONI Alpha tubulin OS=Picea wilsonii GN=TUA1 PE=2 SV=1 Length = 45

  5. Effects of a Multimodule Curriculum of Palliative Care on Medical Students

    OpenAIRE

    Stanley S.L. Tsai; Wen-Yu Hu; Hao-Hsiang Chang; Shan-Chwen Chang; Chin-Yu Chen; Tai-Yuan Chiu

    2008-01-01

    The objective of this study was to investigate the effects of educational intervention using a multimodule curriculum of palliative care on medical students, and to explore significant factors that influence improvement in beliefs of ethical decision-making. Methods: A total of 259 medical students enrolled in the “Family, Society and Medicine” course, and accepted a multimodule palliative care curriculum that included a 1-hour lecture, 1 hour of patient contact, 1 hour of literature readi...

  6. The Falls City Engineers: A History of the Louisville District Corps of Engineers United States Army

    Science.gov (United States)

    1974-12-24

    General Butler , and Colonel Clay , were side-wheelers designed for sen’ice in the Gulf of ~lexico.23 Activities of the Louiscille Office, 1849-1852...131 Gary, Ind. , 241 Gates , Ralph F ., 259 General Butler , steamboat, 96 324 General Hamer, steamboat, 96 General Hanna , steamboat, 138...of Ohio, Snags, and names of rivers Octavia , dredge, 118 Office of Chief of Engineers (OCE), see Chief of Engineers Office of Emergency

  7. Test plan for measuring ventilation rates and combustible gas levels in RPP active catch tanks

    Energy Technology Data Exchange (ETDEWEB)

    NGUYEN, D.M.

    1999-06-03

    T Plant is the primary decontamination facility for the Hanford Site, and also performs waste handling, verification, and repackaging. This Interim Operational Safety Requirement (IOSR) document provides required limits, programs, and administrative controls at the T Plant Complex. It is to be used in conjunction with HNF-SD-WM-ISB-006, Interim Safety Basis (ISB) for Solid Waste Facilities (T Plant), and HNF-2896, Safety Assessment for Project W-259, which is an addendum to the ISB.

  8. Northeast Artificial Intelligence Consortium Annual Report. Volume 2. 1988 Discussing, Using, and Recognizing Plans (NLP)

    Science.gov (United States)

    1989-10-01

    Encontro Portugues de Inteligencia Artificial (EPIA), Oporto, Portugal, September 1985. [15] N. J. Nilsson. Principles Of Artificial Intelligence. Tioga...FI1 F COPY () RADC-TR-89-259, Vol II (of twelve) Interim Report October 1969 AD-A218 154 NORTHEAST ARTIFICIAL INTELLIGENCE CONSORTIUM ANNUAL...7a. NAME OF MONITORING ORGANIZATION Northeast Artificial Of p0ilcabe) Intelligence Consortium (NAIC) Rome_____ Air___ Development____Center

  9. European Scientific Notes. Volume 34. Number 5,

    Science.gov (United States)

    1980-05-31

    Lafayette, IN) in which in conjunction with a hypodermic 259 A __ ____ ____ ESN 34-S (1980) needle guided by B-scan visualization, to measure the...Oceanography 4 Meteorology Mr. T.C. Cheston Underwater Acoustics 4 Radar Dr. P. Pire Communications and Information Theory Dr. N.A. Greenfield Radiological...Research 4 Systems Analysis CDR R.D. Matulka Aerospace Systems Dr. J. Neighbours Physics CDR S.E. Sokol Weapons Systems LCDR C.H. Spikes Environmental

  10. Damage Mechanics Model Development for Monocrystalline Superalloys (PREPRINT)

    Science.gov (United States)

    2010-02-01

    R. Wheeler, D.M. Dimiduk, Ultramicroscopy, in press. [5] Groeber, Ghosh, Haley , Uchic, Dimiduk, Materials Characterization 57 (2006) 259-273. [6...of Microscopy 201 (2001) 388-394. [4] M.D. Uchic, M. De Graef, R. Wheeler, D.M. Dimiduk, Ultramicroscopy, in press. [5] Groeber, Ghosh, Haley , Uchic...were measured using the Laue x-ray with the help of Jay Tiley and Paul Shade. 79 (a) (b) Figure 3.6.1. Images of the butterfly coil

  11. Influence of sedimentation on the geomorphology of the northwestern continental margin of India

    Digital Repository Service at National Institute of Oceanography (India)

    Chauhan, O.S.; Almeida, F.; Suneethi, J.

    milliontonsofsedimentsannually.Thereareotherbullet6uvialsources(Figure1)alongthestudyarea;prominentamongthemaretheTapi,Narmada,Mahi,andSabarmatiRiversintheKhambhatregion.TheregionalphysiographyoftheslopeofftheNWcontinentalmarginofIndia(Gujarat –Maharashtra...Director,NationalInstituteofOceanography,DonaPaula,Goaforprovidingfacilities.ThanksarealsoduetoDr.R.R.Nairforfruitfuldiscussionsandcommentsonthemanuscript.ThisarticlewasoriginallypresentedasapaperatIGCP369,Goa. AddresscorrespondencetoDr.OnkarS.Chauhan,NationalInstituteofOceanography,DonaPaula,Goa403004,India.E-mail:onkar@csnio.ren.nic.in 259 260 O.S.Chauhanetal. FIGURE1Locationofthesurveytracksinthestudyarea.toseparateouttheinbullet6uencesofbullet6...

  12. Secular trends in seasonal variation in birth weight

    DEFF Research Database (Denmark)

    B. Jensen, Camilla; Gamborg, Michael; Raymond, Kyle

    2015-01-01

    - June) and became the highest from 1964 to 1989. The amplitude of the fall peak started at 25.5 (95%CI 24.6; 25.9) grams and gradually disappeared. The amplitude of the early summer peak gradually arose from nothing to a peak of 18.6 (95%CI 17.7; 19.6) grams in the mid 1980s where it started to decrease...

  13. Crystal structure of ethyl 2-[2-((1E-{(1E-2-[2-(2-ethoxy-2-oxoethoxybenzylidene]hydrazin-1-ylidene}methylphenoxy]acetate

    Directory of Open Access Journals (Sweden)

    Joel T. Mague

    2015-01-01

    Full Text Available The complete molecule of the title compound, C22H24N2O6, is generated by crystallographic inversion symmetry and is approximately planar (r.m.s. deviation of the non-H atoms = 0.134 Å. The packing consists of inter-digitated sheets inclined at 25.9 (4° to one another and linked by short C—H...O hydrogen bonds.

  14. [Increasing incidence of community-acquired pneumonia caused by atypical microorganisms].

    Science.gov (United States)

    Tazón-Varela, M A; Alonso-Valle, H; Muñoz-Cacho, P; Gallo-Terán, J; Piris-García, X; Pérez-Mier, L A

    2017-09-01

    Knowing the most common microorganisms in our environment can help us to make proper empirical treatment decisions. The aim is to identify those microorganisms causing community-acquired pneumonia. An observational, descriptive and prospective study was conducted, including patients over 14 years with a clinical and radiographic diagnosis of community-acquired pneumonia during a 383 consecutive day period. A record was made of sociodemographic variables, personal history, prognostic severity scales, progress, and pathogenic agents. The aetiological diagnosis was made using blood cultures, detection of Streptococcus pneumoniae and Legionella pneumophila urinary antigens, sputum culture, influenza virus and Streptococcus pyogenes detection. Categorical variables are presented as absolute values and percentages, and continuous variables as their means and standard deviations. Of the 287 patients included in the study (42% women, mean age 66±22 years), 10.45% died and 70% required hospital admission. An aetiological diagnosis was achieved in 43 patients (14.98%), with 16 microorganisms found in 59 positive samples. The most frequently isolated pathogen was Streptococcus pneumonia (24/59, 41%), followed by gram-negative enteric bacilli, Klebsiella pneumonia, Escherichia coli, Serratia marcescens and Enterobacter cloacae isolated in 20% of the samples (12/59), influenza virus (5/59, 9%), methicillin-resistant Staphylococcus aureus (3/59, 5%), Pseudomonas aeruginosa (2/59, 3%), Moraxella catarrhalis (2/59, 3%), Legionella pneumophila (2/59, 3%), and Haemophilus influenza (2/59, 3%). Polymicrobial infections accounted for 14% (8/59). A high percentage of atypical microorganisms causing community-acquired pneumonia were found. Copyright © 2016 Sociedad Española de Médicos de Atención Primaria (SEMERGEN). Publicado por Elsevier España, S.L.U. All rights reserved.

  15. Jet-Lag Syndrome

    Science.gov (United States)

    2002-11-01

    Hampton SM, Morgan LM, Lawrence L et al., Postprandial and metabolic responses in simulated shift work. J. Endocrinol. 1996, 151 : 259-267. Klein KE... metabolic responses , some of which may be long term risk factors for heart disease (Hampton et al., 1996). These symptoms are obviously undesirable...interaction with the environment. For example sleep lowers body temperature and exercise raises body temperature. Therefore the rhythm which we observe

  16. Interspecifc hybrid plants obtained from cultivars (AA) crossed with wild Oryza species (CC)

    Institute of Scientific and Technical Information of China (English)

    TANGShengxiang; YANHuthuang; HuHulying

    1994-01-01

    Wild dee O.officinalis(CNW 258, CNW 259) and O. eichingeri (CNW 260, CNW 261) have CC genome and high resistance to brown planthopper (BPH) and whitebacked planthopper (WBPH). To transfer the resistant gene(s) of the wild rice into Asian cultivated rice, the interspecific crosses between O. sativa L. (AA) and O. officinafis and O.eiclungeri (CC) was made in present study.

  17. 新闻(英文)

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Garment&Accessories Export in May Increased0.52%from Previous Month According to Customs Bureau,theireport and export of China were 164.127billion USD in May,down 25.9%from sameperiod last year.The accumulated importand export from Jan.to May reached763.491 billion USD.down 24.7%.The accumulated export of textiles(excluded those in Chaper 94)in first five

  18. Proceedings of the Department of Defense Breast Cancer Research Program Meeting for Era of Hope, Held in Baltimore, Maryland on 25-28 June 2008

    Science.gov (United States)

    2008-06-01

    invasiveness. Addition of breast myoepithelial cells [a kind gift of K. Polyak (Dana-Farber)] reduces the prote- olysis and reverses the invasive phenotypes of...Gelman and K. Polyak . 2007. Molecular definition of breast tumor heterogeneity. Cancer Cell 11: 259-73. This work was supported by the U.S. Army...Sonenshein1 1Boston University School of Medicine and 2Boston University Goldman School of Dental Medicine Lysyl oxidase is an extracellular enzyme

  19. Feasibility of SH2 Binding as a Prognostic and Diagnostic Indicator: Probing the Tyrosine Phosphorylation State in Breast Cancer by Src Homology 2 Domain Binding

    Science.gov (United States)

    2005-08-01

    binding preferences by peptide library screening . This proteomic approach permits the rapid and comprehensive analysis of global patterns of SH2...described above were determined by combinatorial phosphopeptide library screening [6,7,59,61.109,165,255----258], mutagenesis [259.266] or structural...mediating specific interactions. Phosphopeptide not yet been identified in these species [46.48]. Until three- library screening indicated the consensus

  20. Crystal Structure of the Urokinase Receptor in a Ligand-Free Form

    DEFF Research Database (Denmark)

    Xu, Xiang; Gårdsvoll, Henrik; Yuan, Cai;

    2012-01-01

    . The crystal structure of human uPAR in its ligand-free state would clarify this issue, but such information remains unfortunately elusive. We now report the crystal structures of a stabilized, human uPAR (H47C/N259C) in its ligand-free form to 2.4 Å and in complex with amino-terminal fragment (ATF) to 3.2 Å...

  1. Air Power and Maneuver Warfare

    Science.gov (United States)

    1994-07-01

    der Luftwaffe, Wehrwissenschaftliche Abteilung, "Der Einsatz der Operativen Luftwaffe gegen Polen ," ibid., T-971J19/000877ff./25-9. 40. Richard...1968), 140; Herhudt von Rohden, "Die Plannung and Vorbereitung des Luftkriegs gegen Polen 1939," Luftkrieg, no. 5, appendix 6, 1946. 41 . Ibid., 49...Kriegswissenschaftliche) Abteilung, "Vortrag ueber der Luftkrieg in Polen 1939: 23 July 1944," GMR, T-971/18/00264/21 . 46 . "Der Einsatz der Operativen

  2. Main: 3SC2 [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 3SC2 小麦 Bread Wheat Triticum aestivum Serine Carboxypeptidase Ii Chains A And B Nam... 1WHS; X-ray; A=6-260, B=266-418.|PDB; 1WHT; X-ray; A=5-260, B=266-418.|PDB; 3SC2; X-ray; A=1-259, B=266-417...WHDAPRSMLPIYRELIAAGLRIWVFSGDTDAVVPLTATRYSIGALGLPTTTSWYPWYDDQEVGGWSQVYKGLTLVSVRGAGHEVPLHRPRQALVLFQYFLQGKPMPGQTKNAT wheat_3SC2.jpg ...

  3. The Philippine Insurrection: The U.S. Navy in a Military Operation Other Than War, 1899-1902

    Science.gov (United States)

    2004-12-01

    under General Antonio Luna presented formable defenses around Calumpit, and again in conjunction with the terrain and weather, took a toll on the...opening through the CINC Asiatic to naval vessels. The ports of Nueva Caceres and Pasacao on Luzon were opened for coastal trade on February 28, 1900. On...capital of Nueva Caceres, the army was greatly aided by the gunboat’s efforts, and took the capital on the 22nd.259 On February 23, 1900, the town of

  4. ANALYSIS OF FACTORS DEPENDING INNOVATIVE ACTIVITY OF ORGANIZATIONS OF MOSCOW REGION

    Directory of Open Access Journals (Sweden)

    Svetlana N. Zhuravlev

    2015-01-01

    Full Text Available The article gives a detailed analysis ofthe views of the organizations surveyedby economic activity. Due to the fact that the share of the manufacturing sector ofthe Moscow region in 2012. It accountedfor 23.1% of the GRP it is advisable to start with the sector. Manufacturing in accordance with the approved classification are divided into high-tech (110 surveyed organizations, high-medium technology(259 organizations and low-level andlow-tech.

  5. Domain Modeling: NP_001074911.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001074911.1 chr19 EXTRACELLULAR REGION OF THE HUMAN RECEPTOR NKP46 c1p6fa_ chr19/NP_001074911....1/NP_001074911.1_apo_218-419.pdb c1olla_ chr19/NP_001074911.1/NP_001074911.1_holo_218-419.pdb blast 256Y,257K,258E,259G,292Q,293Y,294R,296Y EDO 1 ...

  6. Phasic Dopaminergic Signaling and the Presymptomatic Phase of Parkinson’s Disease

    Science.gov (United States)

    2005-07-01

    anatomy and headinjury, ni magerostheintria do n s behavior. Behavioural Brain Research 28:259-274. head injury, damage to the intrinsic neurons Lindner...Gilliam P, Vaughn D, Wilcox RE (1982) nidate. Behavioural Brain Research , in press. Tactile extinction: Distinguishing between sensori- Fleming SM...test. Behavioural Brain Research , in press. decorticate rats. Behavioral Neuroscience 98:518-540. Greenough WT, Pass B, DeVoogd T (1976) The influ

  7. Proceedings of the International Congress (12th), Corrosion Control for Low-Cost Reliability, Held in Houston, Texas on September 19 -24, 1993. Volume 6. Electric Power Industry

    Science.gov (United States)

    1993-09-24

    Resistance of Alumina Coated Iron to Alkali Carbonate at 700*C M. Okuyama, T. Noshiro, and S. Kambe ........................ 259 Paper # Page # Paper...Acid Pretreatments when S. Granese, A. Fernandez, and B. Rosales ........................... 652 Activated with Aluminium Hydroxide E. Almeida and 0...deposit comprised of lake sediment and biomass formed on the surface of the sample. RESULTS AND DISCUSSION Hypochlorination Experiments ii) Type 304L

  8. The Prospective Contribution of Childhood Maltreatment to Low Self-Worth, Low Relationship Quality, and Symptomatology Across Adolescence: A Developmental-Organizational Perspective

    OpenAIRE

    Flynn, Megan; Cicchetti, Dante; Rogosch, Fred

    2014-01-01

    This research investigated the prospective contribution of childhood maltreatment to low self-worth, low relationship quality, and symptoms during adolescence. Further, the stability and cross-lagged effects of these sequelae of maltreatment were examined over time. History of maltreatment during childhood was obtained, and youth (407 maltreated, 228 nonmaltreated; 376 males, 259 females) completed two subsequent assessments spaced approximately two years apart during early-mid and mid-late a...

  9. A Laboratory Study of the Effects of Diet and Bright Light Countermeasures to Jet Lag

    Science.gov (United States)

    1990-03-01

    within a food group using the nutrition handbook for diabetics as a reference (14]. At dinner on the day before the shift occurred (Day 7), a subject in...publication. 34 References [1] Lewy AJ, Wehr TA, Goodwin FK, Newsome DA and Markey SP. Light suppresses melatonin secretion in humans. Science 210:1267-1269... Melatonin Production: Shifting "Dawn" and "Dusk" Shifts the Dim Light Melatonin Onset (DLUMO). Annals New York Academy of Sciences 453:253-259, 1985

  10. Youth Attitude Tracking Study: Spring 1980.

    Science.gov (United States)

    1980-08-01

    recall content 29.0 25.9 -3.1 No Have Not Seen/Heard Advertising .7.8 33.4 -4.4 No Base:* (1050) (1010) Source: Question 6a * The reduced bases . efle ...YOU!RSELF AND PURPOSE Or THE SURVEY IF TALKING WITH A NEW RESPONDENT:) lie’lo 1c,mi of Mr.ket Facts, Incorporated. Nay ! please speak with Wle are con*1

  11. A Structured Reasoning Space for Design of Complex, Socio-Technical Systems

    Science.gov (United States)

    2006-10-01

    is desirable. 46 JFC Guidance I JFACC Director triategy C ombat Plans Combat Intelience , Air Mobilitystm~yB•.• ~ er ir ttck•m Operations Survelll=ie...Science and Engineering, 12), New York: Elsevier Science Ltd. 73 Sacerdoti, E. D. (1974). Planning in a hierarchy of abstraction spaces. Artificial ... Artificial Intelligence, 8, 259-283. Lintern, Gavan (2004). Dissensions in Work Domain Analysis. Workshop on Cognitive Work Analysis, Seattle, WA

  12. Composite augmentation phalloplasty: personal experience after 275 patients

    OpenAIRE

    Juan Monreal

    2015-01-01

    Aim: To report the author's experience in augmentation phalloplasty by studying a retrospective series of patients who underwent fat grafting for girth enhancement or a composite technique based on suspensory ligament release plus fat grafting performed simultaneously. Methods: The author analyzed retrospectively the outcomes of 275 augmentation phalloplasty procedures performed in 259 patients until November 2013. Of these, 127 correspond to girth augmentation with fat grafting and 148 to co...

  13. Perturbation and Pitch Normalization as Enhancements to Speaker Recognition

    Science.gov (United States)

    2009-04-01

    Representation", Proc. ICASSP 2003, vol. I, pp.256-259, 2003. [4] Marrero, V. et al. "Identifying speaker-dependent acoustic parameters in Spanish vowels ...Meeting of the Acoustical Society of America, June 4-8, 2007 [8] Reynolds, D. A. “ Comparison of Background Normalization Methods for Text...improvements across disparate conditions. This paper demonstrates that acoustic perturbation, in this case analysis, distortion, and resynthesis of

  14. [Epidemiological survey of dysphonia in children at primary school entry].

    Science.gov (United States)

    Lecoq, M; Drape, F

    1996-01-01

    The study of 259 children in primary school revealed a prevalence of dysphonia of 10%, often undiagnosed, untreated or considered as benign. It would seem desirable to draw attention to this symptom, which may be an indication of organic pathology or of psychological problems, the early treatment of which may avoid later sequelae. It is sometimes necessary to allow a period for reflection in order to gain the cooperation of the child and his parents.

  15. Annotated Bibliography for Lake Erie. Volume IV. Physical,

    Science.gov (United States)

    1974-10-01

    chlorine and alka- lis, and organic mercury compounds. The latter are as slimi- cides used in the pulping industry. Mercury is incorporated and...livestock and poultry production is concentrated are also potential sources of serious pollution. In Ohio, animal-waste pollu- tion problems are being...bridge between Huron and Ontario. (BU) 235. Farwell, Oliver A. 1925. Botanical gleanings in Michigan. Am. Mid. Nat. 9(7):259. 102 Brief account of

  16. Analysis of Investigational Drugs in Biological Fluids. Method Development and Routine Assay. Appendix A.

    Science.gov (United States)

    2007-11-02

    simultaneously on eleven projects (I-WR 238,605, 2-halofantrine (and its metabolite), 3-WR 6026 (and its metabolites), 4- mefloquine (and its metabolite), 5...chloroquine (and its metabolites), and 11-a multiple drug interaction study in dog plasma for WR 238,605, mefloquine , chloroquine, quinine,, doxycycline...245 Study Report 18, WR 6026 in Plasma ................................................................ 259 Study Report 19, Mefloquine (Free Base

  17. High-Throughput Sequencing of Germline and Tumor From Men with Early-Onset Metastatic Prostate Cancer

    Science.gov (United States)

    2015-10-01

    molecularly profile both the initial prostate cancer (PR-259) and the liver biopsy which contained histologically-confirmed small cell/neuroendocrine...Therefore, we modified our approach to use archived FFPE biopsy and prostatectomy tumor specimen and to analyze these specimens using a qPCR...number alterations are indicated. 4 with small cell carcinoma of the liver and eventually succumbed from this disease approximately one year from

  18. Measuring Noncommissioned Officer Knowledge and Experience to Enable Tailored Training

    Science.gov (United States)

    2011-11-01

    robustly predictive of broad psychological constructs (Goska & Ackerman, 1996; Gottfredson, 1998; Jensen, 1998; Thorndike , 1985). However, general...An aptitude-treatment interaction approach to transfer within training. Journal of Educational Psychology , 88 (2), 249-259. Gottfredson, L. S... Educational Psychology , 96 (3), 558-568. McNamara, D. S., Kintsch, E., Songer, N. B., & Kintsch, W. (1996). Are good texts always better? Interactions of

  19. Do Capacity Coupled Electric Fields Accelerate Tibial Stress Fracture Healing

    Science.gov (United States)

    2006-12-01

    MJ, Goll SR, Nichols CE, 3rd, Pollack SR: Prevention and treatment of sciatic denervation disuse osteoporosis in the rat tibia with capacitively...the healing of fractures. J Bone Joint Surg Am 83-A:259-70, 2001 40. Rubin CT, McLeod KJ, Lanyon LE: Prevention of osteoporosis by pulsed...USA Corresponding author Belinda R. Beck, Ph.D. Griffith University School of Physiotherapy and Exercise Science, PMB 50 Gold Coast Mail Centre Q

  20. Improving the Tools of Symbolic Learning.

    Science.gov (United States)

    1987-09-01

    FUNDING/SPONSORING 8b OFFICE SYMBOL 9. PROCUREMENT INSTRUMENT IDENTIFICATION NUMBER OR ’iNIZATIONI Of applicable) USARDSG(UK) ERO DAJA45-85-c-0014 k...UPCPEANV WOPKJ.VG SESSION ON LEA.RNING :E’WSL 86 283-4/02/2986 (260 pages) Aor 25.9 COMPTE RENDUS DE LA jOURNEE FR%;ANCALSE SUp L ’ APPRENTISSAGE JFA 86 5

  1. Defense Acquisition Research Journal. Volume 19, Number 3, Issue 63, July 2012

    Science.gov (United States)

    2012-07-01

    Acquisition University http://www.dau.mil Keywords: Agile, Systems Engineering, Information Technology (IT), DoD Agile IT Acquisition, IT Box, Scrum ...individuals and 71 countries, found Scrum and eXtreme Programming to be the most widely followed method- ologies (VersionOne, 2007). Other common...http://www.dau.mil 259 Defense ARJ, July 2012, Vol. 19 No. 3 : 249–264 Scrum Scrum is a framework used for project management, which is designed for

  2. Purifying and Testing Gecko Skin Compounds, a Promising Attractant for Small Brown Treesnakes

    Science.gov (United States)

    2012-03-13

    499. Keiser, D., D. Keiser, and B. H. Brattstrom. 2011. Coluber (=Masticophis) flagellum (Coachwhip). Unusual feeding behavior. Herpetological ...juvenile Brown Treesnakes (Boiga irregularis). Herpetological Conservation and Biology 4:313-323. Rodda, G. H., K. Dean-Bradley, and T. H. Fritts...2005. Glueboards for estimating lizard abundance. Herpetological Review 36:252–259. Rodda, G. H., Fritts, T. H., Clark, C. S., Gotte, S. W. and Chiszar

  3. Muramyl Peptide-Enhanced Sleep: Pharmacological Optimization of Performance

    Science.gov (United States)

    1988-06-01

    tious challenges. For example, in human infants, mild upper respiratory tract infections, which were associated with rhinitis but not with fever, did not...wakefulness in the rat. Neuroendocrinology 18: 1-18, 1975. 34. von Economoc, C.V. Sleep as a problem of localization. J. Nerv. Mental Dis. 71: 249-259, 1930. 35...N. Ling, and W.B. Wehrenberg. Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly . Science 218: 585-587, 1982. 52

  4. Data of evolutionary structure change: 1CNYA-1RJ5B [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available -7.732 14.011 15.259 1.00 14.49 C -map> PHE ASP GLY TYR LYS THR ... PHE CA -map> VAL CA 540 HIS CA 529 TR... ATOM 3045 CA LEU B 131 19.494 9.945 -22.868 1.00 53.30 C ... CA 3.79 LEU CA -map> VAL CA 537 -map>

  5. Powerplant lubricant selection for improved efficiency and environmental impact reduction

    OpenAIRE

    Simmons, Gregory F; Kuznetsov, Evgeny; Glavatskih, Sergei

    2012-01-01

    Computational models were used to optimize bearing performance by adjusting a number of lubricant properties. This computational optimization showed that the most beneficial characteristics to hydrodynamic bearing operation were high viscosity index (VI) and high specific heat capacity. Four environmentally adapted synthetic lubricants were developed to provide these characteristics including: ISO VG32 with 259 VI, ISO VG22 with 245 VI, ISO VG22 with 336 VI, and ISO VG15 with 226 VI. A full s...

  6. In Search of an Effective in vivo Reactivator for Organophosphorus Nerve Agent-Inhibited Acetylcholinesterase in the Central Nervous System

    Science.gov (United States)

    2012-01-01

    Berends, D.M.W. Elskamp, L.A. Kepner, E. Meeter and R.P.L.S. Visser, The prophylactic value of oximes against organophosphate poisoning , In: SIPRI...new antidote drug combination (Atropine-HI-6-prodiazepam) for treatment of organophosphate poisoning , Eur. J. Pharm. Sci., 9(2000), 259–263. [9] J...Clement, Efficacy of pro-PAM (N-methyl-1,6-dihydropyridine-2- carbaldoxime hydrochloride) as a prophylaxis against organophosphate poisoning

  7. Tertiary Oximes on Brain Acetylcholinesterase and Central Excitatory Effects of Nerve Agents

    Science.gov (United States)

    2012-01-01

    quences of Organophosphate Poisoning in the CNS, Transworld Research Network: Kerala, India, pp. 111-133. 18. Shih T-M, Skovira JW, O’Donnell, JC and...Benschop HP, De Jong LRA, Vink JAJ, et al. 1976. The prophylactic value of oximes against organophosphate poisoning . In: SIPRI, Medical Protection...for treatment of organophosphate poisoning , Eur. J. Pharm. Sci. 9: 259–263. 24. Vallejo-Freire AA. 1951. A simple technique for repeated collection

  8. INTEGRAL detection of high energy emission from XMMSL1 J171900.4-353217

    DEFF Research Database (Denmark)

    Ishibashi, W.; Bozzo, Enrico; Terrier, Mereghetti, Paizis, Ducci, Gotz, Bazzano, Fiocchi, De Rosa, Tarana, Del Santo, Natalucci, Panessa, Capitanio, Sguer, Bianchin, Watanabe, Kuiper, Barragan, -

    2010-01-01

    the IBIS/ISGRI FOV for a total exposure time of 170 ks and was detected at a significance level of 6.5 sigma (20-40 keV energy band). The best fit position obtained from the OSA software is at RA: 259.738 DEC: -35.508 (J2000), with an associated error of 3.9 arcmin. The ISGRI spectrum is best fit...

  9. Medical Surveillance Monthly Report (MSMR). Volume 10, Number 2, April 2004

    Science.gov (United States)

    2004-04-01

    6,118 (66) 964 (51) Osteoarthritis 9,882 (68) 6,576 (64) 523 (71) Other shoulder disorders 8,064 (72) 4,898 (72) 270 (86) Rheumatoid arthritis 2,857...malignant neoplasms 4,225 (82) 1,159 (91) 1,631 (40) Oral conditions Dental caries 1,259 (106) 985 (95) 23 (112) Periodontal disease 881 (109) 755 (99

  10. Bibliography of Technical Publications and Papers October 1977 - September 1978

    Science.gov (United States)

    1978-11-01

    hydrolysis . Third Enzyme Conference, US:USSR Technical Exchange, Tallin, Latvia, November 1977. 259. RICHMOND, R. C., and M. SIMIC. Mechanisms of...193. SPANO, L. A., T. H. TASSINARI, C. F. MACY, and E. D. BLACK. Pretreatments and substrate evaluation for the enzymatic hydrolysis of cellulosic... triglyceride . J. Amer. Oil Chem. Soc., 54(11): 502-505 (1977). 213. _, W. W. NAWAR, W. G. YEOMANS, and C. MERRITT, JR. The identification of radiolytic

  11. Exercise and Osteoporosis: A Dose-Response Meta-Analysis

    Science.gov (United States)

    2011-05-01

    derived from our proposed work will have the potential to reduce and/or delay (1) the incidence and prevalence of osteopenia and osteoporosis, (2...perimenopausal women]. Saluda Publica De Mexico 2005 July;47(4):259-67. Ref ID: 332 (56) Ahn S, Song R. Bone mineral density and perceived menopausal...arterial hypertension and osteoporosis:impact of antihypertensive treatment on extracellular metabolism of calcium]. Revista Clinica Espanola 1999

  12. Introduction pages

    OpenAIRE

    2015-01-01

    Introduction Pages and Table of Contents Research ArticlesInsulin Requirements in Relation to Insulin Pump Indications in Type 1 DiabetesPDFGabriela GHIMPEŢEANU, Silvia Ş. IANCU, Gabriela ROMAN, Anca M. ALIONESCU259-263Comparative Antibacterial Efficacy of Vitellaria paradoxa (Shea Butter Tree) Extracts Against Some Clinical Bacterial IsolatesPDFKamoldeen Abiodun AJIJOLAKEWU, Fola Jose AWARUN264-268A Murine Effort Model for Studying the Influence of Trichinella on Muscular Activity of MicePDF...

  13. Investigation of Solidification of High Strength Steel Castings

    Science.gov (United States)

    1961-12-01

    2U9-259. 23. A. Kohn: "Etude de I’homogeneisation des segregations dendritiques de phosphore et ’ rsenic dans les aciers ...de la structure en bandes dans 1’ acier forge", Memoires Scientifiques de la Revue de Metallurgie, v. «j£, 6, I96I, pp. 423-^3...dans les aciers ". Revue de Metallurgie, February i960, pp. 117-134. 35. R. Castro and A. Gueussier: "La fragilite des aciers speciaux

  14. Cohort study of predictive value of urinary albumin excretion for atherosclerotic vascular disease in patients with insulin dependent diabetes

    DEFF Research Database (Denmark)

    Deckert, T; Yokoyama, H; Mathiesen, E

    1996-01-01

    up. SETTING: Diabetes centre in Denmark. SUBJECTS: 259 patients aged 19-51 with insulin dependent diabetes of 6-34 years' duration and without atherosclerotic vascular disease or diabetic nephropathy at baseline. MAIN OUTCOME MEASURES: Baseline variables: urinary albumin excretion, blood pressure......OBJECTIVE: To examine whether slightly elevated urinary albumin excretion precedes development of atherosclerotic vascular disease in patients with insulin dependent diabetes independently of conventional atherogenic risk factors and of diabetic nephropathy. DESIGN: Cohort study with 11 year follow...

  15. Carbohydrate Supplementation and Immune Responses After Acute Exhaustive Resistance Exercise

    Science.gov (United States)

    2008-01-01

    marathon race. Journal of Applied Physiology, 91, 109–114. Nieman, D.C., & Pedersen, B.K. (2000). Nutrition and exercise immunology. Boca Raton, FL...247 International Journal of Sport Nutrition and Exercise Metabolism, 2008, 18, 247-259 © 2008 Human Kinetics, Inc. Carlson is with the Dept. of...similar for the 2 days before the testing sessions. Diet analyses were calculated using the Nutrition III diet-analysis software by N-Square Computing

  16. Are Students with High Ability in Math More Motivated in Math and Science than Other Students?

    Science.gov (United States)

    Andersen, Lori; Cross, Tracy L.

    2014-01-01

    Expectancy-value motivation profiles were identified in a sample of US ninth-grade students in 2009 (n = 19,259) using latent profile analysis. Of four distinct profiles, two were high, one typical, and one low in math and in science. In each area, the two high profiles were distinguished by (1) high self-efficacy with lower utility value and (2)…

  17. Hypokalemia-induced long QT syndrome with an underlying novel missense mutation in S4-S5 linker of KCNQ1.

    Science.gov (United States)

    Kubota, T; Shimizu, W; Kamakura, S; Horie, M

    2000-09-01

    Congenital long QT syndrome (LQTS) is caused by mutations in at least five genes coding for cardiac potassium or sodium channels that regulate the duration of ventricular action potentials. Acquired LQTS often is associated with drugs or metabolic abnormalities. A 47-year-old woman who presented with marked QT prolongation (QTc = 620 msec(1/2)) and repeated episodes of torsades de pointes associated with hypokalemia (2.6 mEq/L) was screened for mutations in LQTS genes using polymerase chain reaction/single-strand conformation polymorphism (PCR/SSCP). We identified a novel missense mutation in the intracellular linker of S4-S5 domains of KCNQ1, resulting in an amino acid substitution of cysteine for arginine at position 259 (R259C). Whole cell, patch clamp experiments were conducted on COS7 cells transfected with wild-type and/or R259C KCNQ1 with or without KCNE1. Functional analyses of the mutant KCNQ1 subunit on COS7 cells revealed its functional channels in the homozygous state, producing a significantly smaller current than the KCNQ1 channels and a less severe dominant-negative effect on I(Ks). The novel KCNQ1 mutation R259C is the molecular basis for I(Ks) dysfunction underlying an apparently sporadic case of hypokalemia-induced LQTS, consistent with a mild mutation likely to disclose the clinical manifestation of LQTS in a context of severe hypokalemia. Our findings suggest that gene carriers with such mild mutations might not be so rare as commonly expected in patients with acquired LQTS, and stress the importance of mutational analysis for detecting either "silent" forms of congenital LQTS or de novo mutations.

  18. Workloads and occupational accidents in a rural environment

    OpenAIRE

    Laurelize Pereira Rocha; Marta Regina Cezar-Vaz; Marlise Capa Verde de Almeida; Anelise Miritz Borges; Mara Santos da Silva; Janaína Sena-Castanheira

    2015-01-01

    Se tuvo como objetivo verificar los tipos de cargas de trabajo recurrentes del trabajo de la agricultura, conforme reconocimiento de los trabajadores e identificar los accidentes de trabajo ocurridos entre los agricultores de dos ambientes rurales. Estudio cuantitativo, exploratorio y descriptivo realizado con 259 agricultores en Río Grande del Sur, por medio de cuestionario semiestructurado. Se utilizo el análisis descriptivo, y los testes Chi cuadrado de Pearson y Coeficiente de Contingenci...

  19. The 98th Canton Fair Ended with Ample Fruits

    Institute of Scientific and Technical Information of China (English)

    Bai Yifeng

    2005-01-01

    @@ The 98th Canton Fair was held in Guangzhou, Canton province from October 15 to October 20. The exhibition site was about 259 thousand sq.meters, more than 12 thousand outstanding domestic suppliers participated in the fair. 150 thousand kinds of high-quality Chinese goods,including industry type, textile and garment type, pharmaceutical and health-care type, daily consumption commodities type and gift type, which were shown in 34 exhibition areas.

  20. The 98th Canton Fair Ended with Ample Fruits

    Institute of Scientific and Technical Information of China (English)

    Bai; Yifeng

    2005-01-01

      The 98th Canton Fair was held in Guangzhou, Canton province from October 15 to October 20. The exhibition site was about 259 thousand sq.meters, more than 12 thousand outstanding domestic suppliers participated in the fair. 150 thousand kinds of high-quality Chinese goods,including industry type, textile and garment type, pharmaceutical and health-care type, daily consumption commodities type and gift type, which were shown in 34 exhibition areas.……

  1. Associations between belief in conspiracy theories and the maladaptive personality traits of the personality inventory for DSM-5

    OpenAIRE

    Swami, V.; Weis, L.; Ley, A.; Barron, D.; Furnham, A.

    2015-01-01

    Conspiracy theories can be treated as both rational narratives of the world as well as outcomes of underlying maladaptive traits. Here, we examined associations between belief in conspiracy theories and individual differences in personality disorders. An Internet-based sample (N=259) completed measures of belief in conspiracy theories and the 25 facets of the Personality Inventory for DSM-5 (PID-5). Preliminary analyses showed no significant differences in belief in conspiracy theories across...

  2. The Unreliable M/M/1 Retrial Queue in a Random Environment

    Science.gov (United States)

    2012-01-01

    quasi-toeplitz markov chains and their application in queueing theory. Queueing Systems: Theory and Applications, 54:245– 259, 2006. [26] V. G. Kulkarni...assume the environment is an ergodic continuous-time Markov chain (CTMC) on a finite state space. We analyze this system using classical matrix...process can be viewed as an asymptotically quasi-Toeplitz Markov chain . Using results from [25], they determine the stability condition and devise an

  3. Domain Modeling: NP_060272.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_060272.3 chr7 Crystal structure of a protein phosphatase 2A (PP2A) holoenzyme. p2pf4d_ chr7/NP_060272.3.../NP_060272.3_apo_209-817.pdb p2iaea_ chr7/NP_060272.3/NP_060272.3_holo_209-817.pdb psi-blast 259P,260Q,298V MLL 1 ...

  4. File list: NoD.PSC.20.AllAg.hESC_derived_mesendodermal_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.PSC.20.AllAg.hESC_derived_mesendodermal_cells hg19 No description Pluripotent s...tem cell hESC derived mesendodermal cells SRX142799,SRX088771,SRX142789,SRX088893,SRX259074,SRX142792,SRX259...e.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.PSC.20.AllAg.hESC_derived_mesendodermal_cells.bed ...

  5. File list: NoD.PSC.50.AllAg.hESC_derived_mesendodermal_cells [Chip-atlas[Archive

    Lifescience Database Archive (English)

    Full Text Available NoD.PSC.50.AllAg.hESC_derived_mesendodermal_cells hg19 No description Pluripotent s...tem cell hESC derived mesendodermal cells SRX142799,SRX088771,SRX142789,SRX088893,SRX259074,SRX142792,SRX259...e.biosciencedbc.jp/kyushu-u/hg19/assembled/NoD.PSC.50.AllAg.hESC_derived_mesendodermal_cells.bed ...

  6. Rational Design of Therapeutic and Diagnostic Against Botulinum Neurotoxin

    Science.gov (United States)

    2006-12-01

    Gram-positive bacilli bacterium, Clostridium botulinum, which can be found worldwide in soil. Clostridium tetani is a similar bacterium to C...B: Biological Sciences, 354, 259-268. 6. Nantel, A.J. (1999). Clostridium Botulinum. WHO international programme on chemical safety poisons...of Clostridium botulinum C1 neurotoxin. Nucleic Acids Research, 18, 4924. 20. Binz, T., Kurazono, H., Popoff, M.R., Eklund, M.W., Sakaguchi, G

  7. Great III - Cultural Resource Inventory. Volume 2

    Science.gov (United States)

    1982-05-01

    Historical Sketch of St. Louis University. Patrick Fox, • St. Louis. Historical look at the St. Louis mound complex. Holmes, Nathaniel 1868 Loess...Saint Louis to Me. St. Louis, Missouri: Hawthorn Pub- lishing Company, 1978. 305 p., illus. £ates, Giwendolyn Lewis 1976 Historic Sites Inventory for...Watercolors by Marilynne Bradley. St. Louis: Hawthorn Publishing Company, c. 1977. 259 p., illus. (part color). Includes: Old Courthouse, Old

  8. A cereal-based evening meal rich in indigestible carbohydrates increases plasma butyrate the next morning

    DEFF Research Database (Denmark)

    Nilsson, Anne C; Östman, Elin M; Knudsen, Knud Erik Bach

    2010-01-01

    , mean ± SD: 25.9 ± 3.2 y, BMI consumed all test meals in a random order on separate evenings. At a standardized breakfast following evening test meals...... concentrations the following morning compared with an evening meal with white wheat bread (P involving colonic fermentation and generation of SCFA, where in particular...... butyric acid may be involved. This mechanism may be one explanation by which whole grain is protective against type 2 diabetes and cardiovascular disease....

  9. Diketopiperazines and Sesquilignans from the Branches and Leaves of Claoxylon polot.

    Science.gov (United States)

    Gu, Hong-Shun; Ma, Shuang-Gang; Li, Li; Qu, Jing; Liu, Yun-Bao; Yu, Shi-Shan

    2015-06-01

    Six new diketopiperazines (1-6), two new sesquilignans (7-8), and ten known compounds (9-18) were isolated from the branches and leaves of Claoxylon polot. Their structures were elucidated by extensive spectroscopic analysis. The absolute configurations of 1-3 were assigned by computational methods. Compounds 1 and 2 exhibited antiviral activity against Coxsackie B3 virus with IC50 values of 14.6 and 25.9 µM, respectively.

  10. Extended-spectrum-beta-lactamase-producing Enterobacteriaceae in Yaounde, Cameroon

    OpenAIRE

    Gangoue Pieboji, Joseph; Bedenic, B.; Koulla-Shiro, S.; Randegger, C.; Adiogo, D.; Ngassam, P.; Ndumbe, P; Hachler, H.

    2005-01-01

    Organisms producing extended-spectrum beta-lactamases (ESBLs) have been reported in many countries, but there is no information on the prevalence of ESBL-producing members of the family Enterobacteriaceae in Cameroon. A total of 259 Enterobacteriaceae strains were isolated between 1995 and 1998 from patients at the Yaounde Central Hospital in Cameroon. Enterobacterial isolates resistant to extended-spectrum cephalosporin and monobactam were screened for ESBL production by the double-disk (DD)...

  11. Extended-Spectrum-β-Lactamase-Producing Enterobacteriaceae in Yaounde, Cameroon

    OpenAIRE

    Gangoué-Piéboji, Joseph; Bedenic, Branka; Koulla-Shiro, Sinata; Randegger, Corinne; Adiogo, Dieudonné; Ngassam, Pierre; Ndumbe, Peter; Hächler, Herbert

    2005-01-01

    Organisms producing extended-spectrum β-lactamases (ESBLs) have been reported in many countries, but there is no information on the prevalence of ESBL-producing members of the family Enterobacteriaceae in Cameroon. A total of 259 Enterobacteriaceae strains were isolated between 1995 and 1998 from patients at the Yaounde Central Hospital in Cameroon. Enterobacterial isolates resistant to extended-spectrum cephalosporin and monobactam were screened for ESBL production by the double-disk (DD) sy...

  12. Book Review Imaginary modernity and tradition. Architecture of the twentieth century in Latin America / Reseña del Libro Imaginarios de modernidad y tradición. Arquitectura del siglo XX en América Latina

    Directory of Open Access Journals (Sweden)

    Adolfo Benito Narváez Tijerina

    2016-10-01

    Full Text Available Book Review Imaginary modernity and tradition. Architecture of the twentieth century in Latin America Reseña del Libro Imaginarios de modernidad y tradición. Arquitectura del siglo XX en América Latina. Ettinger, Catherine R. (coord. (2015. Imaginarios de modernidad y tradición. Arquitectura del siglo XX en América Latina. México: Miguel Ángel Porrúa, 259 páginas. ISBN: 978-6074019681.

  13. Real Options in Defense R and D: A Decision Tree Analysis Approach for Options to Defer, Abandon, and Expand

    Science.gov (United States)

    2016-12-01

    1995). The options approach to capital investment. Harvard Business Review , 73(3), 105–15. Retrieved from https://hbr.org Ehrhardt, M. C., & Brigham...options. Financial Management, 22(3), 259–270. doi:10.2307/3665943 Kester, W. C. (1984). Today’s options for tomorrow’s growth. Harvard Business Review ...Getting started on the numbers. Harvard Business Review , 76(4), 51–67. Magee, J. F. (1964a). Decision trees for decision making. Harvard Business

  14. Upgrade of RIBLL

    Institute of Scientific and Technical Information of China (English)

    SunZhiyu; ZhanWenlong; XiaoGuoqing; GuoZhongyan; XuHushan

    2003-01-01

    The synthesis of the super-heavy nuclei and the study of their properties attract more and more attentions in recent years. The He-jet+MG wheel technique with which 259Db and 265Bh were synthesized at IMP has reached its limits due to the short life-time and rare amount of the products. In order to identify the nuclei with higher Z, a device for separating the interested nuclei from the heavy background is definitely needed.

  15. Characterization and Modulation of Proteins Involved in Sulfur Mustard Vesication

    Science.gov (United States)

    2000-06-01

    p53 may negatively regulate p53-mediated transcriptional activation of genes important in the cell cycle and apoptosis ( Malanga and Althaus, 1997...differentiation in vitro. J. Cell. Physiol. 163, 105-114. Malanga , M., and Althaus, F. (1997). Poly(ADP-ribose): a negative regulator of p53 functions. In The 12th...Aggarwal, B. (1996) J. Interferon ribosylation Reactions, Cancun, Mexico Cytokine Res. 16, 259-267 59. Malanga , M., and Althaus, F. (1997) in The

  16. Leukemoid reaction in a patient with acute lymphoblastic leukemia following the

    Directory of Open Access Journals (Sweden)

    Osman Yokuş

    2013-06-01

    Full Text Available The occurrence of persistent neutrophilic leukocytosisabove 50,000 cells/μL for reasons other thanleukemia is defined as leukemoid reaction. Chronicmyelogenous leukemia (CML and chronic neutrophilicleukemia (CNL should be excluded, and underlyingdiseases or causes should be examined,in differential diagnosis. The most commonly observedcauses of leukemoid reactions are severeinfections, intoxications, malignancies, severe hemorrhage,or acute hemolysis [1]. J Clin Exp Invest2013; 4 (2: 258-259

  17. Functions and Mechanisms of Sleep in Flies and Mammals

    Science.gov (United States)

    2009-10-01

    International Mass Spectrom etry Conference; Bremen, Germany: Oral presentation, September 2009. th Tissue Prep aration for the in situ MALDI MS Im...Muscarinic and GABAA receptors modulate acetylcholine release in feline basal forebrain. Eur J Neurosci 17:249-259. Birren Personnel Susan Birren...Vertes, 2004; McDermott et al. 2003). Secondly, gene expression studies of sleep were limited by the use of tissue homogenates that dilute changes in

  18. Schutz vor AIDS in neuen Partnerschaften

    OpenAIRE

    Elbers, Klaus; Montada, Leo

    1990-01-01

    Wer schützt sich vor AIDS in einer neuen Partnerschaft durch Kondombenutzung? Hierzu wurde eine Fragebogenuntersuchung an 259 Studenten aus verschiedenen Fachbereichen durchgeführt. Die zentrale Frage betraf die Kondombenutzung bei Gelegenheit des zeitlich letzten sexuellen Erstkontaktes mit einer neuen Partnerin, einem neuen Partner und die Erfassung von Motiven und Barrieren, die gegen eine Kondombenutzung bestehen. Darüber hinaus wurden viele AIDS-relevante Überzeugungen, Motive, Verantwor...

  19. Pericardium-6 Acupressure for the Prevention of Postoperative Nausea and Vomiting

    Science.gov (United States)

    1999-10-01

    conducted to provide information to the anesthesia community on the use of acupressure for the prevention of postoperative nausea and vomiting. It was...that is expected in this study (Dr. Levine, personal communication , Feb 13, 1998). An attempt was made to recruit approximately 50 subjects into the...background . Journal of Nurse- Midwifery , 37(4), 254-259. Beal, M. (1992b). Acupuncture and related treatment modalities part II: Applications to

  20. Proceedings of Biological Actions of Extracellular ATP Conference Held in Philadelphia, Pennsylvania on 27-19 November 1990. (Annals of the New York Academy of Sciences. Volume 603)

    Science.gov (United States)

    1990-12-16

    Daly & V. C. ManganmellS. Eds: 254-259. Springer.Verlag New York. NY. 25. BLACK. J W 1987 In Perspecttves on Receptor Clasification J W. Black, D H...noctratides on the cyclic adenosine 3,5’-phosphate content of guirma pig cerebral caries slices Mot Phar- macal 6: 13-23 39 BRUNiS, R F & J It FERGoUS 1989

  1. Rab3 interacting molecule 3 mutations associated with autism alter regulation of voltage-dependent Ca²⁺ channels.

    Science.gov (United States)

    Takada, Yoshinori; Hirano, Mitsuru; Kiyonaka, Shigeki; Ueda, Yoshifumi; Yamaguchi, Kazuma; Nakahara, Keiko; Mori, Masayuki X; Mori, Yasuo

    2015-09-01

    Autism is a neurodevelopmental psychiatric disorder characterized by impaired reciprocal social interaction, disrupted communication, and restricted and stereotyped patterns of interests. Autism is known to have a strong genetic component. Although mutations in several genes account for only a small proportion of individuals with autism, they provide insight into potential biological mechanisms that underlie autism, such as dysfunction in Ca(2+) signaling, synaptic dysfunction, and abnormal brain connectivity. In autism patients, two mutations have been reported in the Rab3 interacting molecule 3 (RIM3) gene. We have previously demonstrated that RIM3 physically and functionally interacts with voltage-dependent Ca(2+) channels (VDCCs) expressed in neurons via the β subunits, and increases neurotransmitter release. Here, by introducing corresponding autism-associated mutations that replace glutamic acid residue 176 with alanine (E176A) and methionine residue 259 with valine (M259V) into the C2B domain of mouse RIM3, we demonstrate that both mutations partly cancel the suppressive RIM3 effect on voltage-dependent inactivation of Ba(2+) currents through P/Q-type CaV2.1 recombinantly expressed in HEK293 cells. In recombinant N-type CaV2.2 VDCCs, the attenuation of the suppressive RIM3 effect on voltage-dependent inactivation is conserved for M259V but not E176A. Slowing of activation speed of P/Q-type CaV2.1 currents by RIM3 is abolished in E176A, while the physical interaction between RIM3 and β subunits is significantly attenuated in M259V. Moreover, increases by RIM3 in depolarization-induced Ca(2+) influx and acetylcholine release are significantly attenuated by E176A in rat pheochromocytoma PC12 cells. Thus, our data raise the interesting possibility that autism phenotypes are elicited by synaptic dysfunction via altered regulation of presynaptic VDCC function and neurotransmitter release.

  2. Immunoproteomic analysis of bacterial proteins of Actinobacillus pleuropneumoniae serotype 1

    Directory of Open Access Journals (Sweden)

    Wu Zongfu

    2011-06-01

    Full Text Available Abstract Background Actinobacillus pleuropneumoniae (APP is one of the most important swine pathogens worldwide. Identification and characterization of novel antigenic APP vaccine candidates are underway. In the present study, we use an immunoproteomic approach to identify APP protein antigens that may elicit an immune response in serotype 1 naturally infected swine and serotype 1 virulent strain S259-immunized rabbits. Results Proteins from total cell lysates of serotype 1 APP were separated by two-dimensional electrophoresis (2DE. Western blot analysis revealed 21 immunoreactive protein spots separated in the pH 4-7 range and 4 spots in the pH 7-11 range with the convalescent sera from swine; we found 5 immunoreactive protein spots that separated in the pH 4-7 range and 2 in the pH 7-11 range with hyperimmune sera from S259-immunized rabbits. The proteins included the known antigens ApxIIA, protective surface antigen D15, outer membrane proteins P5, subunit NqrA. The remaining antigens are being reported as immunoreactive proteins in APP for the first time, to our knowledge. Conclusions We identified a total of 42 immunoreactive proteins of the APP serotype 1 virulent strain S259 which represented 32 different proteins, including some novel immunoreactive factors which could be researched as vaccine candidates.

  3. Factors Influencing Residency Program Selection by Medical Students Pursuing Obstetrics and Gynecology.

    Science.gov (United States)

    Alston, Meredith J; Metz, Torri D; Fothergill, Russell; Meg Autry, Amy; Wagner, Sarah A; Allshouse, Amanda A; Stephenson-Famy, Alyssa

    2017-02-01

    Little is known about the factors that influence medical student selection of obstetrics and gynecology (ob-gyn) residency programs. We assessed the factors influencing residency program selection by fourth-year medical students pursuing ob-gyn training. A voluntary, anonymous, 19-question survey of residency selection factors was distributed to all fourth-year medical students interviewing at 1 of 5 academic ob-gyn departments for a residency position during the 2013-2014 interview season. Participants were surveyed about the relative importance (not important, somewhat important, important) of various residency selection factors, including operative experience, exposure to subspecialties, curricular experience, access to fellowships, and administrative aspects of residency, including adherence to duty hour restrictions. Of 322 potential respondents, 262 (81%) completed the survey. Surgical training and training in laparoscopic surgery were deemed "important" by nearly all respondents (98%, 258 of 262, and 97%, 253 of 262, respectively). Factors that were considered "not important" by a significant group of respondents included maternity/paternity leave policies (22%, 58 of 259); opportunity for international rotations/electives (20%, 51 of 259); exposure to quality and safety initiatives (13%, 34 of 259); and training in abortion (13%, 34 of 262). Fourth-year medical students identified surgical training as the most important factor in selecting an ob-gyn residency, a finding that is particularly relevant as decreasing and changing surgical volumes affect residency training in this specialty.

  4. Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling▿

    Science.gov (United States)

    Molzan, Manuela; Schumacher, Benjamin; Ottmann, Corinna; Baljuls, Angela; Polzien, Lisa; Weyand, Michael; Thiel, Philipp; Rose, Rolf; Rose, Micheline; Kuhenne, Philipp; Kaiser, Markus; Rapp, Ulf R.; Kuhlmann, Jürgen; Ottmann, Christian

    2010-01-01

    The Ras-RAF-mitogen-activated protein kinase (Ras-RAF-MAPK) pathway is overactive in many cancers and in some developmental disorders. In one of those disorders, namely, Noonan syndrome, nine activating C-RAF mutations cluster around Ser259, a regulatory site for inhibition by 14-3-3 proteins. We show that these mutations impair binding of 14-3-3 proteins to C-RAF and alter its subcellular localization by promoting Ras-mediated plasma membrane recruitment of C-RAF. By presenting biophysical binding data, the 14-3-3/C-RAFpS259 crystal structure, and cellular analyses, we indicate a mechanistic link between a well-described human developmental disorder and the impairment of a 14-3-3/target protein interaction. As a broader implication of these findings, modulating the C-RAFSer259/14-3-3 protein-protein interaction with a stabilizing small molecule may yield a novel potential approach for treatment of diseases resulting from an overactive Ras-RAF-MAPK pathway. PMID:20679480

  5. Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.

    Science.gov (United States)

    Molzan, Manuela; Schumacher, Benjamin; Ottmann, Corinna; Baljuls, Angela; Polzien, Lisa; Weyand, Michael; Thiel, Philipp; Rose, Rolf; Rose, Micheline; Kuhenne, Philipp; Kaiser, Markus; Rapp, Ulf R; Kuhlmann, Jürgen; Ottmann, Christian

    2010-10-01

    The Ras-RAF-mitogen-activated protein kinase (Ras-RAF-MAPK) pathway is overactive in many cancers and in some developmental disorders. In one of those disorders, namely, Noonan syndrome, nine activating C-RAF mutations cluster around Ser(259), a regulatory site for inhibition by 14-3-3 proteins. We show that these mutations impair binding of 14-3-3 proteins to C-RAF and alter its subcellular localization by promoting Ras-mediated plasma membrane recruitment of C-RAF. By presenting biophysical binding data, the 14-3-3/C-RAFpS(259) crystal structure, and cellular analyses, we indicate a mechanistic link between a well-described human developmental disorder and the impairment of a 14-3-3/target protein interaction. As a broader implication of these findings, modulating the C-RAFSer(259)/14-3-3 protein-protein interaction with a stabilizing small molecule may yield a novel potential approach for treatment of diseases resulting from an overactive Ras-RAF-MAPK pathway.

  6. 犬新孢子虫NcAMA1基因重组腺病毒穿梭质粒的构建及其真核表达%Construction and eukaryotic expression of the recombinant adenovirus shuttle plasmid with NcAMA1 gene of Neospora caninum

    Institute of Scientific and Technical Information of China (English)

    郭焕平; 贾立军; 于龙政; 薛书江; 高洋; 李男礼; 张守发

    2014-01-01

    为构建犬新孢子虫NcAMA1基因重组腺病毒穿梭质粒,并在真核细胞中表达,以重组质粒pVAX1-NcAMA1为模板,PCR扩增了NcAMA1基因,以此构建了pMD18T-NcAMA1重组克隆质粒;对该重组克隆质粒进行双酶切鉴定后,将其亚克隆至腺病毒穿梭载体pCR259中.应用脂质体介导转染法将经PCR鉴定和酶切鉴定正确的pCR259-NcAMA1重组穿梭质粒转染293细胞,应用IFAT和Western-blot技术检测了AMA1基因在293细胞中的表达情况.结果显示,扩增的NcAMA1基因长度为1 695 bp,构建的重组腺病毒穿梭质粒pCR259-NcAMA1能在293细胞中获得瞬时表达,表达蛋白的分子质量约为68 ku.

  7. Initial thoracic involvement in lymphoma. CT assessment; Afectacion toracica inicial en el linfom. Valoracion con TC

    Energy Technology Data Exchange (ETDEWEB)

    Bustos, A.; Corredoira, J.; Ferreiros, J.; Cabeza, B.; Jorquera, M.; Pedrosa, I.; Martinez, R.; Fernandez, C. [Hospital Clinico San Carlos. Madrid (Spain)

    2002-07-01

    To analyze the initial thoracic involvement by CT in a consecutive series of patients with lymphoma. A retrospective analysis was made of thoracic CT studies made at the time of diagnosis of 259 patients with lymphoma. Mediastinal pulmonary, pleural, pericardial and chest wall involvement was assessed by CT. Of 259 patients (129 men y 130 women), 56 had Hodgkin's disease (HD) and 203 had non-Hodgkin lymphoma (NHL). Forty-two percent (42.5%, 110/259) of the patients had chest involvement on CT: 33 of 56 patients with HD (58.9%) and 77 of 203 patients with NHL (37.9%). All the patients with thoracic HD and 71.4% of patients with thoracic NHL, had mediastinal lymph node involvement. of the patients with thoracic involvement 12.1% (4/33) of the patient with HD and 23.3% (18/77) of the patients with NHL had pulmonary involvement. Thoracic involvement on CT was more frequent in HD. Mediastinal lymph node involvement was the most common finding fundamentally in HD. Pulmonary disease always occurred in the presence of mediastinal lymph node involvement in HD but could occur as an isolated finding in NHL. (Author) 24 refs.

  8. Characterization of HIV Transmission in South-East Austria.

    Science.gov (United States)

    Hoenigl, Martin; Chaillon, Antoine; Kessler, Harald H; Haas, Bernhard; Stelzl, Evelyn; Weninger, Karin; Little, Susan J; Mehta, Sanjay R

    2016-01-01

    To gain deeper insight into the epidemiology of HIV-1 transmission in South-East Austria we performed a retrospective analysis of 259 HIV-1 partial pol sequences obtained from unique individuals newly diagnosed with HIV infection in South-East Austria from 2008 through 2014. After quality filtering, putative transmission linkages were inferred when two sequences were ≤1.5% genetically different. Multiple linkages were resolved into putative transmission clusters. Further phylogenetic analyses were performed using BEAST v1.8.1. Finally, we investigated putative links between the 259 sequences from South-East Austria and all publicly available HIV polymerase sequences in the Los Alamos National Laboratory HIV sequence database. We found that 45.6% (118/259) of the sampled sequences were genetically linked with at least one other sequence from South-East Austria forming putative transmission clusters. Clustering individuals were more likely to be men who have sex with men (MSM; pAustria had at least one putative inferred linkage with sequences from a total of 69 other countries. In conclusion, analysis of HIV-1 sequences from newly diagnosed individuals residing in South-East Austria revealed a high degree of national and international clustering mainly within MSM. Interestingly, we found that a high number of heterosexual males clustered within MSM networks, suggesting either linkage between risk groups or misrepresentation of sexual risk behaviors by subjects.

  9. Integrating tuberculosis and HIV care in rural Rwanda

    Science.gov (United States)

    Gasana, M.; Vandebriel, G.; Kabanda, G.; Tsiouris, S. J.; Justman, J.; Sahabo, R.; Kamugundu, D.; El-Sadr, W. M.

    2016-01-01

    SETTING Rwanda has generalised human immunodeficiency virus (HIV) and tuberculosis (TB) epidemics. The Rwandan Ministry of Health approved a policy on TB-HIV collaborative activities in 2005. The present study is a report on the results of the integrated TB and HIV activities at a rural health care site between July 2005 and June 2006. METHODS Activities included provider-initiated HIV testing and counselling (PITC) of TB patients and the implementation of a standardised TB screening questionnaire for in-patients on medical wards and HIV-infected out-patients. RESULTS Of a total 259 TB patients registered, 87% with unknown HIV status or who were HIV-negative accepted PITC. Overall, 48% (125/259) of TB patients were HIV-infected. The proportion of TB patients ever tested for HIV increased from 82% (138/169) in 2004–2005 to 93% (240/259) in 2005–2006 (P < 0.001). Of the 770 in-patients screened for TB, 162 (21%) tested positive, of whom 53 (33%) were diagnosed with TB; 39 (76%) of these were HIV co-infected. Three hundred out-patients with HIV were screened for TB; 80 (27%) tested positive, of whom 11 (14%) were diagnosed with TB. DISCUSSION Activities integrating TB and HIV were feasible in a rural health care setting. PITC was successful in TB patients and unrecognised TB was common, particularly among HIV-infected in-patients. PMID:18302821

  10. Discovery of the Coolest Extreme Subdwarf

    CERN Document Server

    Burgasser, A J; Burgasser, Adam J.

    2006-01-01

    We report the discovery of LEHPM 2-59 as the coolest extreme M subdwarf (esdM) found to date. Optical and near infrared spectroscopy demonstrate that this source is of later spectral type than the esdM7 APMPM 0559-2903, with the presence of strong alkali lines (including Rb I), VO absorption at 7400 A and H2O absorption at 1.4 microns. Current optical classification schemes yield a spectral type of esdM8, making LEHPM 2-59 one of only two ultracool esdMs known. The substantial space velocity of this object (V_galactic ~ -180 km/s) identifies it as a halo star. Spectral model fits to the optical and near infrared spectral data for this and four other late-type esdMs indicate that LEHPM 2-59 is the coolest esdM currently known, with Teff = 2800-3000 K and -1.5 <~ [M/H] <~ -2.0. Comparison of Teff determinations for M dwarfs and esdMs based on spectral model fits from this study and the literature demonstrate a divergence in Teff scales beyond spectral types M5/esdM5, as large as 600-800 K by types M8/esdM...

  11. A replication study of GWAS-derived lipid genes in Asian Indians: the chromosomal region 11q23.3 harbors loci contributing to triglycerides.

    Directory of Open Access Journals (Sweden)

    Timothy R Braun

    Full Text Available Recent genome-wide association scans (GWAS and meta-analysis studies on European populations have identified many genes previously implicated in lipid regulation. Validation of these loci on different global populations is important in determining their clinical relevance, particularly for development of novel drug targets for treating and preventing diabetic dyslipidemia and coronary artery disease (CAD. In an attempt to replicate GWAS findings on a non-European sample, we examined the role of six of these loci (CELSR2-PSRC1-SORT1 rs599839; CDKN2A-2B rs1333049; BUD13-ZNF259 rs964184; ZNF259 rs12286037; CETP rs3764261; APOE-C1-C4-C2 rs4420638 in our Asian Indian cohort from the Sikh Diabetes Study (SDS comprising 3,781 individuals (2,902 from Punjab and 879 from the US. Two of the six SNPs examined showed convincing replication in these populations of Asian Indian origin. Our study confirmed a strong association of CETP rs3764261 with high-density lipoprotein cholesterol (HDL-C (p = 2.03×10(-26. Our results also showed significant associations of two GWAS SNPs (rs964184 and rs12286037 from BUD13-ZNF259 near the APOA5-A4-C3-A1 genes with triglyceride (TG levels in this Asian Indian cohort (rs964184: p = 1.74×10(-17; rs12286037: p = 1.58×10(-2. We further explored 45 SNPs in a ∼195 kb region within the chromosomal region 11q23.3 (encompassing the BUD13-ZNF259, APOA5-A4-C3-A1, and SIK3 genes in 8,530 Asian Indians from the London Life Sciences Population (LOLIPOP (UK and SDS cohorts. Five more SNPs revealed significant associations with TG in both cohorts individually as well as in a joint meta-analysis. However, the strongest signal for TG remained with BUD13-ZNF259 (rs964184: p = 1.06×10(-39. Future targeted deep sequencing and functional studies should enhance our understanding of the clinical relevance of these genes in dyslipidemia and hypertriglyceridemia (HTG and, consequently, diabetes and CAD.

  12. 高碳水化合物条件下鼠肌 GLUT4表达与CaMK/HDAC5关系的研究%Relationship between GLUT4 Expression and CaMK/HDAC5 in Rat Skeletal Muscle under Different Carbohydrates

    Institute of Scientific and Technical Information of China (English)

    刘建武; 万家川; 李良刚

    2013-01-01

    To find out whether the effect of Caffeine on regulating the GLUT4 expression was related with Caffeine-Ca2+-CaMKⅡ-HDAC5 signal pathway.48 male Wistar rats which were 8-week-old were randomly divided into four groups ( n=12 ) , named as HGC group, HGK group, LGC group and LGK group.The rats were fed with different diet and induced by Caffeine or KN62.And CaMKⅡ(Thr286)、HDAC5(Ser498) and HDAC5(Ser259)phosphorylation and GLUT4 protein expression were tested by western blotting.Compared with the LGK group, both CaMKⅡ(Thr286) and HDAC5(Ser259) and HDAC5(Ser498)phosphorylation increased significantly in skeletal muscle cells in LGC group.Compared with the LGK and LGC group, CaMKⅡ(Thr286)、HDAC5(Ser498) and HDAC5(Ser259)phosphorylation decreased obviously in HGC and HGK group. Meanwhile, the changes of CaMKⅡ(Thr286)、HDAC5(Ser498) and HDAC5(Ser259)phosphorylation in HGC group had no significant difference with that in HGK group.Therefore (1) Caffeine could remarkably increase the expression of GLUT4, and increase the CaMKⅡ(Thr286)、HDAC5 (Ser498) and HDAC5(Ser259)phosphorylation and exist a remarkably positive correlation.While KN62 could significantly decrease the CaMKⅡ(Thr286)、HDAC5(Ser498) and HDAC5(Ser259)phosphorylation and the expression GLUT4.They demonstrated that the effect of Ca2+signal which was induced by Caffeine on increasing the expression of GLUT4 was possibly related with Caffeine-Ca2+-CaMKⅡ-HDAC5 signal pathway. (2) Whatever the rats were fed with, the expression of GLUT4 was corresponded with CaMKⅡ(Thr286)、HDAC5(Ser498) and HDAC5(Ser259) in skeletal muscle cells.So the effect of CaMKⅡon regulating the expression of GLUT4 in skeletal muscle was related with inducing HDAC5 and regulating its (Ser 498) site and(Ser 259)site.%观察Caffeine诱导骨骼肌细胞GLUT4表达的潜在分子调控机制是否是Caffeine-Ca2+-CaMKⅡ-HDAC5信号通路。8周龄雄性Wistar大鼠42只,随机分为高碳Caffeine 组( HGC

  13. 曲面体层X线、CT和MRI在髁突骨折诊断中的应用比较%The value of paronamic radiograph, CT and MRI for the diagnosis of condylar fracture

    Institute of Scientific and Technical Information of China (English)

    黄国伟; 郑吉驷; 张善勇; 杨驰

    2014-01-01

    Objective To retrospectively analyze the advantages and disadvantages of radiographic methods commonly used for diagnostic of condylar fractures.Methods From Jan 2002 to Nov 2013,290 patients (405 condylars) in the temporomandibular joint (TMJ) division of Ninth People's Hospital Shanghai Jiao Tong University School of Medicine were diagnosed as condylar fractures.Panoramic films and CT were taken in all patients to check and count the amount of condylar fractures,including intracapsular condyle fracture (type A,B,C and M),condylar neck fracture and subcondylar fracture.MRI was also taken in 119 patients with 174 condylar fractures to check the position of TMJ disc.The data were analyzed and compared among the three examinations in the diagnosis of the condylar fractures.Results Panoramic films showed 79.8% (323/405) condylar fractures.Among condylar fractures,intracapsular condylar fractures,condylar neck fractures and subcondylar fractures accounted for 48.9%(198/405),20.3%(82/405) and 10.6%(43/405)respectively.CT showed 64.0% (259/405) intracapsular condylar fractures,24.0% (97/405) condylar neck fractures and 12.1%(49/405) subcondylar fractures.Among intracapsular condylar fractures,Type A fracture was the most common type of ICF,which accounted for 48.7%(126/259),followed by Type B fracture,which accounted for 30.9%(80/259) and Type M fracture,12.4%(32/259).Type C fracture was the least type which accounted for 8.1% (21/259).According to the diagnostic criteria of CT,there were 10 condylar neck fractures misdiagnosed with intracapsular condylar fractures.MRI showed 94.9% (129/136) TMJ disc displacement in intracapsular condylar fractures,53.6% (15/28) in condylar neck fractures and 60.0% (6/10) in subcondylar fractures.Among intracapsular condylar fractures,there were 95.3%(61/64) TMJ disc displacement in type A,95.2%(40/42) in type B,89.0%(8/9) in type C,and 95.2%(20/21) in type M.There was significant difference of TMJ

  14. The Effect of 17β-Estradiol to Gobiocypris rarus Juvenile Growth and Its Sex Differentiation %17β-雌二醇对稀有鮈鲫(Gobiocypris rarus)幼鱼生长及性分化的影响

    Institute of Scientific and Technical Information of China (English)

    王星; 汤保华; 蔡磊明; 赵玉艳; 于保青; 王捷

    2012-01-01

    [方法]通过51dph(days post hatch)稀有鮈鲫幼鱼在不同质量浓度17β-雌二醇(E2)中经过28 d的流水式暴露研究,观察了E2对稀有鮈鲫幼鱼生长状态、卵黄蛋白原(VTG)含量、性别比率和性腺组织学的影响.[结果]观察发现,与对照组相比,259、1180 ng/LE2处理组中的稀有鮈鲫幼鱼体长生长受到显著性抑制(P≤0.05,P≤0.01);8、48、259 ng/L处理组雌鱼VTG含量水平显著降低(P≤0.01),而雄鱼在1180 ng/L处理组中VTG含量水平显著升高(P≤0.0 1 );通过组织病理学观察,E2对稀有鮈鲫幼鱼雌雄性别比率未产生显著影响,但在48 ng/L处理组出现雌雄间体现象,同时,在259、1180 ng/L处理组中,雄鱼精巢出现明显的萎缩.[结论]17β-雌二醇对51 dph的稀有鮈鲫性腺分化产生了雌激素效应,但用稀有鮈鲫作为筛选和评价内分泌干扰物的活体试验模型还需要进一步研究.%[Methods] In present study, 51 days post hatch (dph) juveniles of rare minnows (Gobiocypris raws) were exposed to various concentrations of 17β-estradiol for 28 days in flow-through conditions. Growth performance, vitellogenin, sex ratio and gonadal histopathology were analyzed. [Results] Compared with control, the results showed that the length increase was inhibited at 259 and 1180 ng/L (P≤0.05, P≤0.01). And VTG concentrations in female fishes were decreased significantly at 8, 48 and 259 ng/L E2 treated groups (p≤0.01), and in male fishes were increased significantly at 1180 ng/L E2 treated group (P≤0.01) compared with control. Based on histopathologic examination, no obviously difference in sex ratio was found between the treatment and control groups, however, intersex was found at 48 ng/L E2 treatment group, and at 259, 1180 ng/L E2 treatment groups, male fishes spermaries appeared visibly depauperate. [Conclusions] 17β-Estradiol performed estrogenic effects on gonads differentiation of the 51 dph juveniles of rare minnows, and it need to

  15. 牛新孢子虫NcSRS2基因腺病毒穿梭载体的构建及在293细胞中的表达%Construction of bovine Neospora caninum NcSRS2 adenovirus shuttle vector and expression of NcSRS2 gene in 293 cells

    Institute of Scientific and Technical Information of China (English)

    贾立军; 张守发; 刘明明

    2012-01-01

    应用PCR技术扩增牛新孢子虫NcSRS2基因,纯化PCR产物后与克隆载体pMD18-T Simple Vector连接,将PCR、酶切鉴定及测序分析正确的pMD-18T-NcSRS2重组质粒进行EcoRⅠ和XbaⅠ双酶切,克隆至相同酶切回收后的腺病毒穿梭载体pCR259中,再将PCR、酶切鉴定正确的pCR259-NcSRS2重组质粒转染293细胞,应用IF-AT和Western-blotting技术检测重组质粒在293细胞中的表达情况。结果显示,扩增的牛新孢子虫NcSRS2基因长度为1 227bp,与GenBank中发表的NcSRS2(AF061249)核苷酸序列同源性为99%,构建的pCR259-NcSRS2重组质粒在293细胞中得到瞬时表达,表达蛋白的相对分子质量为43 000,具有较好的反应原性。本试验为新孢子虫病腺病毒载体疫苗的构建奠定了基础。%In this research,bovine Neospora caninum NcSRS2 gene was amplified by PCR.The purified PCR products were ligated with pMD18-T simple vector.After enzyme digestion and sequence analysis,the correct pMD-18T-NcSRS2 gene was digested by EcoRⅠand XbaⅠ,and cloned into the adenovirus shuttle vector pCR259 which was digested by the same enzymes.The correct pCR259-NcSRS2 recombinant plasmid was transfected into 293 cells.The expression of recombinant plasmid in 293 cells was detected by IFAT and Western-blotting.The result shows that the length of bovine Neospora caninum NcSRS2 gene is 1 227 bp.which has 99% homology with sequence and sequence in GenBank.The pCR259-NcSRS2 recombinant plasmid could transiently express in 293 cells.The molecular weight of the expressed protein which has good reactionogenicity is 43 000.This research laid the foundation for the construction of Neospora caninum vector-adenovirus vaccine

  16. Complicações e óbitos nas operações para tratar a obesidade mórbida Complications and deaths in operations to treat morbid obesity

    Directory of Open Access Journals (Sweden)

    Aluísio Stol

    2011-12-01

    Full Text Available RACIONAL: A cirurgia bariátrica, apesar de complexa, apresenta baixa morbimortalidade; contudo, quando presente apresenta graves conseqüências. OBJETIVO: Avaliar a presença de complicações e óbitos nos pacientes portadores de obesidade mórbida submetidos a tratamento cirúrgico. MÉTODOS: Análise retrospectiva de 656 pacientes submetidos a procedimento cirúrgico bariátrico. Foram analisados: sexo, idade, peso pré-operatório, índice de massa corporal pré-operatório, procedimento realizado, tempo de internação, complicações pós-operatórias e mortalidade. RESULTADOS: A idade variou entre 16 a 68 anos (média de 36,6 anos. Do total, 80,7% eram do sexo feminino. O índice de massa corporal médio foi de 42,8 kg/m2 (35 e 68 kg/m2 O tempo médio de internação foi de 4,5 dias (1 a 125 dias. O bypass gástrico foi realizado em 370 pacientes (56,40% e a operação de Capella em 236 casos (35,97%. A principal complicação encontrada foi fístula, em 17 pacientes (2,59%. Houve necessidade de reoperação em 17 pacientes (2,59%. Oito pacientes morreram (1,21%, três foram submetidos à operação de Capella, três à bypass, um à opração de Scopinaro e um à gastrectomia vertical. CONCLUSÃO: A principal complicação foi a fístula digestiva, que ocorreu em 2,59% e a mortalidade foi de 1,21%.BACKGROUND: Bariatric surgery, although complex, has low morbidity and mortality, but when they happen, serious consequences are expected in patients evolution. AIM:To evaluate the presence of complications and deaths in patients with morbid obesity who underwent surgical treatment. METHODS: Retrospective analysis of 656 patients undergoing bariatric surgery. Were analyzed: sex, age, pre-operative weight, body mass index before surgery, procedure performed, length of hospital stay, post-operative complications and mortality. RESULTS: The age ranged from 16 to 68 years (mean 36.6 years. Of the total, 80.7% were female. The mean body mass index

  17. Circadian Behavioral Study: LED vs Cool White Fluorescent - 0.1, 1, 10, 40, 80 lux. Part 2

    Science.gov (United States)

    Holley, Daniel C.; Syrkin, N.; Mele, G.

    2000-01-01

    Currently, the light source most commonly used in animal habitat lighting is cool white fluorescent (CWF) light. It was the objective of this study to evaluate a novel LED light source for use in animal habitat lighting by comparing its effectiveness to CWF light in producing and maintaining a normal circadian entrainment. The LED and CWF lights had similar spectral power distributions. Sprague-Dawley rats (175-350 g) were kept individually in metabolic cages, under a strict lighting control: 4 days of acclimation at 12:12 LD, 14 days of 12:12 LD, 14 days of 24:0 LD (free-run), and finally 12:12 LD. Food and water were provided ad libitum. Three behavioral parameters were monitored continuously: gross locomotor activity, drinking, and feeding. Combined mean free run periods (tau) were (mean +/- SEM): 24.6 +/- 0.1 and 24.7 +/- 0.2 at 0.1 lux, 25.5 +/- 0.1 and 25.7 +/- 0.1 at 1.0 lux, 25.3 +/- 0.2 and 25.4 +/- 0.2 at 10 lux, 25.8 +/- 0.1 and 25.9 +/- 0.1 at 40 lux, and 25.9 +/- 0.1 and 25.9 +/- 0.1 at 80 lux, CWF and LED respectively. ANOVA found a significant effect (p lux). LED light sources may be a suitable replacement for conventional light sources used in animal habitat lighting while providing many mechanical and economical advantages.

  18. Efecto del encalado en la respuesta vegetal y fijación simbiótica del nitrógeno en frijol común

    Directory of Open Access Journals (Sweden)

    Aurelio Garc\\u00EDa

    2003-01-01

    Full Text Available En casa de cristales se evaluó mediante el método de valor A, utilizando el isótopo estable 15N, el efecto del encalado de un suelo Rhodic ferralsol sobre la fijación simbiótica de nitrógeno (FSN de los genotipos de frijol común (Phaseolus vulgaris L. BAT 58, BAT 477, DOR 364, CC 25-9 (N. La isolínea NN 125, genotipo de frijol no nodulante, fue utilizado como cultivo de referencia. El efecto del encalado incrementó la fracción de nitrógeno en planta derivado del aire, principalmente en CC 25-9 (N que posee muy poca capacidad de fijación de N atmosf érico cuando no se encala el suelo. Además, se encontró un efecto beneficioso del encalado sobre las reservas de N del suelo, visto que los incrementos de las extracciones totales de N por las plantas provienen del N del aire, e incluso, la cantidad de N en planta derivado del suelo disminuyó para todos los genotipos, principalmente en DOR 364 y CC 25-9(N. Por otra parte, la relación %Nddf/%Ndds, por ciento de N en planta derivado del fertilizante y por ciento de N en planta derivado del suelo respectivamente, varió debido a la aplicación de cal. Por consiguiente, es necesario utilizar dos tratamientos con el cultivo de referencia para evaluar acertadamente la FSN: cultivo de referencia con y sin suelo encalado. Se discute la interpretación del parámetro Eficiencia de Uso del N.

  19. Interaction between O-GlcNAc modification and tyrosine phosphorylation of prohibitin: implication for a novel binary switch.

    Directory of Open Access Journals (Sweden)

    Sudharsana R Ande

    Full Text Available Prohibitin (PHB or PHB1 is an evolutionarily conserved, multifunctional protein which is present in various cellular compartments including the plasma membrane. However, mechanisms involved in various functions of PHB are not fully explored yet. Here we report for the first time that PHB interacts with O-linked beta-N-acetylglucosamine transferase (O-GlcNAc transferase, OGT and is O-GlcNAc modified; and also undergoes tyrosine phosphorylation in response to insulin. Tyrosine 114 (Tyr114 and tyrosine 259 (Tyr259 in PHB are in the close proximity of potential O-GlcNAc sites serine 121 (Ser121 and threonine 258 (Thr258 respectively. Substitution of Tyr114 and Tyr259 residues in PHB with phenylalanine by site-directed mutagenesis results in reduced tyrosine phosphorylation as well as reduced O-GlcNAc modification of PHB. Surprisingly, this also resulted in enhanced tyrosine phosphorylation and activity of OGT. This is attributed to the presence of similar tyrosine motifs in PHB and OGT. Substitution of Ser121 and Thr258 with alanine and isoleucine respectively resulted in attenuation of O-GlcNAc modification and increased tyrosine phosphorylation of PHB suggesting an association between these two dynamic modifications. Sequence analysis of O-GlcNAc modified proteins having known O-GlcNAc modification site(s or known tyrosine phosphorylation site(s revealed a strong potential association between these two posttranslational modifications in various proteins. We speculate that O-GlcNAc modification and tyrosine phosphorylation of PHB play an important role in tyrosine kinase signaling pathways including insulin, growth factors and immune receptors signaling. In addition, we propose that O-GlcNAc modification and tyrosine phosphorylation is a novel previously unidentified binary switch which may provide new mechanistic insights into cell signaling pathways and is open for direct experimental examination.

  20. 护理差错调查分析及防范%Investigation and Analysis caused by nursing mistakes bases on 116 cases and preventive measure

    Institute of Scientific and Technical Information of China (English)

    刘显峰

    2012-01-01

    Objective: Improving the nursing quality and effectively avoiding and preventing the potential nursing mistakes from happening. Methods: We summoned and analysed the cause of nursing mistakes which happened in the hospital in 2010. Results: Nursing error category are accounted for in the first place was check error 72 cases (62.07%) ,the second is the implementation of physiciarrorder error 17 cases (14.65% ), operation error 3 cases (2. 59% ),sample error 3 cases (2.59% ), other 21 cases (18.10% ). Conclusion, We must tighten up the management for the cause of nursing mistakes which happened to the dangerous crowds and in the weak period of time, dangerous offices and dangerous medicine and emergency preplan can be avioded and prevented by nursing mistakes.%[目的]:为了更好地提高护理质量,有效地避免护理差错,防止潜在护理差错的发生.[方法]:针对2010年某院发生的护理差错进行总结、分析.[结果]:护理差错发生类别中占首位的是查对错误72起(62.07%),其次是执行医嘱错误17起(14.65%),操作错误3起(2.59%),标本错误3起(2.59%),其他有21起(18.10%).[结论]:加强对危险人群、薄弱时段、高危科室、高风险药物等的管理及有效的应急预案是避免差错的有效措施.

  1. Evaluation of Flygt Mixers for Application in Savannah River Site Tank Summary of Test Results from Phase A, B, and C Testing

    Energy Technology Data Exchange (ETDEWEB)

    BK Hatchell; H Gladki; JR Farmer; MA Johnson; MR Poirier; MR Powell; PO Rodwell

    1999-10-21

    Staff from the Savannah River Site (SRS), Pacific Northwest National Laboratory (PNNL), Oak Ridge National Laboratory (ORNL), and ITT Flygt Corporation in Trumbull, Connecticut, are conducting a joint mixer testing program to evaluate the applicability of Flygt mixers to SRS Tank 19 waste retrieval and waste retrieval in other U.S. Department of Energy (DOE) tanks. This report provides the results of the Phase C Flygt mixer testing and summarizes the key findings from the Phase A and B tests. Phase C Flygt mixer testing used full-scale, Model 4680 Flygt mixers (37 kW, 51-cm propeller) installed in a fall-scale tank (25.9-m diameter) at SRS. Phase A testing used a 0.45-m tank and Flygt mixers with 7.8-cm diameter propellers. Phase B testing used Model 4640 Flygt mixers (3 kW, 37-cm propeller) installed in 1.8-m and 5.7-m tanks. Powell et al. (1999z4 1999b) provide detailed descriptions of the Phase A and B tests. In Phase C, stationary submerged jet mixers manufactured by ITT Flygt Corporation were tested in the 25.9-m diameter tank at the SRS TNX facility. The Model 4680 mixers used in Phase C have 37-kW (50-hp) electric motors that drive 51-cm (20-in.) diameter propellers at 860 rpm. Fluid velocity was measured at selected locations with as many as four Model 4680 mixers operating simultaneously in the 25.9-m tank, which was filled with water to selected levels. Phase C involved no solids suspension or sludge mobilization tests.

  2. Human mast cells express multiple EP receptors for prostaglandin E2 that differentially modulate activation responses.

    Science.gov (United States)

    Feng, Chunli; Beller, Elizabeth M; Bagga, Savita; Boyce, Joshua A

    2006-04-15

    Prostaglandin E2 (PGE2) blocks mast-cell (MC)-dependent allergic responses in humans but activates MCs in vitro. We assessed the functions of the EP receptors for PGE2 on cultured human MCs (hMCs). hMCs expressed the EP3, EP2, and EP4 receptors. PGE2 stimulated the accumulation of cyclic adenosine monophosphate (cAMP), and suppressed both Fc epsilonRI-mediated eicosanoid production and tumor necrosis factor-alpha (TNF-alpha) generation. PGE2 also caused phosphorylation of extracellular signal-regulated kinase (ERK), exocytosis, and production of prostaglandin D2 (PGD2), as well as leukotriene C4 (LTC4) when protein kinase A (PKA) was inhibited. An EP3 receptor-selective agonist, AE-248, mimicked PGE2-mediated ERK phosphorylation, exocytosis, and eicosanoid formation. Selective agonists of both EP2 and EP4 receptors (AE1-259-01 and AE-329, respectively) stimulated cAMP accumulation. No selective agonist, alone or in combination, was as effective as PGE2. AE-248, AE1-259-01, and AE-329 all inhibited Fc epsilonRI-mediated TNF-alpha generation, while AE1-259-01 blocked eicosanoid production. PGE2 caused the expression of inducible cAMP early repressor (ICER) by a pathway involving PKA and ERK. Thus, while PGE2 activates MCs through EP3 receptors, it also counteracts Fc epsilonRI-mediated eicosanoid production through EP2 receptors and PKA, and blocks cytokine transcription. These functions explain the potency of PGE2 as a suppressor of early- and late-phase allergic responses.

  3. Administrative environmental proceedings in the electromagnetic pollution field; Procedure autorizzatorie nel settore dell'inquinamento da campi elettromagnetici

    Energy Technology Data Exchange (ETDEWEB)

    Fracchia, Fabrizio [Bocconi Univ., Milano (Italy). IDC Istituto di diritto comparato

    2005-05-15

    The aim of the research at issue is to understand the general aspects of administrative environmental proceedings in the electromagnetic pollution field, as they are regulated in Italy both by the Law of February 22, 2001, No. 36 and by the art. 87 of the Legislative Decree of August 1, 2003, No. 259 (by means of this decree, Italy implemented a package of EU Directives -2002/19/EC, 2002/20/EC, 2002/21/EC and 2002/22/EC - in the TLC sector; entered into force on September 16, 2003, it introduced the so-called Unique Code on Electronic Communications) [Italian] Il lavoro ha ad oggetto l'analisi delle procedure autorizzatorie nel settore dell'inquinamento da campi elettromagnetici disciplinate dalla legge 22 febbraio 2001, n. 36 e dall'art. 87, d.lgs. 1 agosto 2003, n. 259 (codice delle comunicazioni elettroniche). Dopo aver registrato la presenza, all'interno di siffatti procedimenti, delle tradizionali funzioni assegnate al procedimento amministrativo, l'indagine individua nel dettaglio i principi stabiliti dalla normativa e i caratteri dell'autorizzazione, indugiando in particolare sul profilo del margine di discrezionalita sussistente in capo all'amministrazione. L'angustia di questo spazio di discrezionalita viene tra l'altro collegato alla rilevanza che, nel settore in esame, risulta avere il principio di precauzione. Specifica attenzione e dedicata al procedimento delineato dall'art. 87, d.lgs. 259/2003, cit.: vengono analizzati i titoli di legittimazione ivi disciplinati, i rapporti con l'istituto della valutazione di impatto ambientale, le fasi procedimentali, la conferenza di servizi e i limiti di applicabilita del meccanismo del silenzio assenso, il tutto avendo come riferimento essenziale il tema della precauzione, il principio di doverosita e la loro valenza normativa.

  4. Characterisation of clinical Staphylococcus aureus isolates harbouring mecA or Panton-Valentine leukocidin genes from four tertiary care hospitals in Indonesia.

    Science.gov (United States)

    Santosaningsih, Dewi; Santoso, Sanarto; Budayanti, Nyoman S; Suata, Ketut; Lestari, Endang S; Wahjono, Hendro; Djamal, Aziz; Kuntaman, Kuntaman; van Belkum, Alex; Laurens, Mitchell; Snijders, Susan V; Willemse-Erix, Diana; Goessens, Wil H; Verbrugh, Henri A; Severin, Juliëtte A

    2016-05-01

    To determine the prevalence, antimicrobial susceptibility profiles and clonal distribution of either methicillin-resistant Staphylococcus aureus (MRSA) or Panton-Valentine leukocidin (PVL)-positive S. aureus obtained from clinical cultures in Indonesian hospitals. S. aureus isolates from clinical cultures of patients in four tertiary care hospitals in Denpasar, Malang, Padang and Semarang were included. We assessed the antimicrobial susceptibility profiles using the Vitek2(®) system, determined the presence of the mecA gene and genes encoding PVL using PCR and analysed the clonal relatedness with Raman spectroscopy. SCCmec typing was performed for all MRSA isolates. Multilocus sequence typing (MLST) was performed for a subset of isolates. In total, 259 S. aureus strains were collected. Of these, 17/259 (6.6%) and 48/259 (18.5%) were MRSA and PVL-positive methicillin-susceptible S. aureus (MSSA), respectively. The prevalence of MRSA and PVL-positive MSSA ranged between 2.5-8.9% and 9.5-29.1%, respectively and depended on geographic origin. PVL-positive MRSA were not detected. Raman spectroscopy of the strains revealed multiple Raman types with two predominant clusters. We also showed possible transmission of a ST239-MRSA-SCCmec type III strain and a ST121 PVL-positive MSSA in one of the hospitals. We showed that MRSA and PVL-positive MSSA are of clinical importance in Indonesian hospitals. A national surveillance system should be set-up to further monitor this. To reduce the prevalence of MRSA in Indonesian hospitals, a bundle of intervention measures is highly recommended. © 2016 John Wiley & Sons Ltd.

  5. 高碳水化合物条件下鼠肌GLUT4表达与CaMK/HDAC5关系的研究

    Institute of Scientific and Technical Information of China (English)

    刘建武; 万家川; 李良刚

    2013-01-01

    观察Caffeine诱导骨骼肌细胞GLUT4表达的潜在分子调控机制是否是Caffeine—Ca2+-CaMKII—HDAC5信号通路。8周龄雄性Wistar大鼠42只,随机分为高碳Caffeine组(HGC)、高碳KN62组(HGK)、低碳Caffeine组(LGC)和低碳KN62组(LGK),每组12只。分别给予不同饮食加Caffeine或KN62刺激。检测caMKⅡ(Thr286)位点、HDAC5(sel498)位点和HDAC5(Ser259)位点磷酸化水平以及GLUT4蛋白表达水平。与HGc组相比LGC组GLUT4蛋白表达、CaMKⅡ(Thr286)、HDAC5(Se-98)HDAC5(Ser259)磷酸化水平都显著增加性高于HGC组和LGK组。无论是在低碳还是在高碳浓度下骨骼肌细胞GLUT4蛋白表达变化都对应着上游caMKⅡ蛋白位点(Thr286)磷酸化水平和下游HDAC5蛋白位点(Ser498)和(Ser259)磷酸化的变化,所以CaMKⅡ调节GLUT4表达的机制至少涉及到CaMKⅡ征用转录抑制子HDAC5。

  6. Toward Incentives for Military Transformation: A Review of Economic Models of Compensation

    Science.gov (United States)

    2005-01-01

    Economic Organization,” The American Economic Review , Vol. 62, No. 5, 1972, pp. 777–795. Asch, Beth J., “Do Incentives Matter? The Case of Navy...Bengt Holmstrom, “Internal Labor Markets: Too Many Theories, Too Few Facts,” The American Economic Review , Vol. 85, No. 2, 1995, pp. 255–259. Baker...Economics, Vol. 18, No. 1, 2000, pp. 1–19. Che, Yeon-Koo, and Seung-Weon Yoo, “Optimal Incentives for Teams,” The American Economic Review , Vol. 91, No. 3

  7. Branching fractions for chi_cJ -> p p-bar pi^0, p p-bar eta, and p p-bar omega

    CERN Document Server

    Onyisi, P U E; Alexander, J P; Cassel, D G; Das, S; Ehrlich, R; Fields, L; Gibbons, L; Gray, S W; Hartill, D L; Heltsley, B K; Hunt, J M; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Sun, W M; Yelton, J; Rubin, P; Lowrey, N; Mehrabyan, S; Selen, M; Wiss, J; Adams, S; Kornicer, M; Mitchell, R E; Shepherd, M R; Tarbert, C M; Besson, D; Pedlar, T K; Xavier, J; Cronin-Hennessy, D; Hietala, J; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Xiao, T; Tomaradze, A; Brisbane, S; Libby, J; Martin, L; Powell, A; Spradlin, P; Wilkinson, G; Mendez, H; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Hu, D; Moziak, B; Napolitano, J; Ecklund, K M; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Ricciardi, S; Thomas, C; Artuso, M; Blusk, S; Mountain, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Lincoln, A; Smith, M J; Zhou, P; Zhu, J; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Randrianarivony, K; Robichaud, A N; Tatishvili, G; White, E J; Briere, R A; Vogel, H

    2010-01-01

    Using a sample of 25.9 million psi(2S) decays acquired with the CLEO-c detector at the CESR e^+e^- collider, we report branching fractions for the decays chi_cJ -> p p-bar pi^0, p p-bar eta, and p p-bar omega, with J=0,1,2. Our results for B(chi_cJ-> p p-bar pi^0) and B(chi_cJ-> p p-bar eta) are consistent with, but more precise than, previous measurements. Furthermore, we include the first measurement of B(chi_cJ-> p p-bar omega).

  8. Exclusive Baryon-Antibaryon Decays of the chi_cJ Mesons

    CERN Document Server

    Naik, P; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A G; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; Méndez, H; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A

    2008-01-01

    Using a sample of 2.59 \\times 10^7 psi(2S) decays collected by the CLEO--c detector, we present results of a study of chi_{cJ} (J=0,1,2) decays into baryon-antibaryon final states. We present the world's most precise measurements of the chi_cJ -> p-pbar and chi_cJ -> Lambda-Lambdabar branching fractions, and the first measurements of chi_c0 decays to other hyperons. These results illuminate the decay mechanism of the chi_c states.

  9. Vibration responses of two house structures during the Edwards Air Force Base phase of the national sonic boom program

    Science.gov (United States)

    Hubbard, Harvey H.

    1990-08-01

    The data are reproduced from NSBEO-1-67, which contains some preliminary results of the test program, and from NASA-Langley working papers 259 and 288 which are now out of print. Included are sample acceleration and strain recordings from F-104, B-58, and XB-70 sonic boom exposures, along with tabulations of the maximum acceleration and strain values measured for each one of about 130 flight tests. These data are compared with similar measurements for engine noise exposures of the building during simulated landing approaches and takeoffs of KC-135 aircraft.

  10. Parámetros genéticos y fenotípicos para peso al año, circunferencia escrotal y talla en ganado Simmental y Simbrah en México

    OpenAIRE

    José Antonio Torres-Vázquez; Coralia Inés Valentina Manzanilla Pech; Aurelio Borrayo Zepeda; Ángel Ríos-Utrera; Vicente Eliezer Vega-Murillo; Guillermo Martínez-Velázquez; Juan José Baeza Rodríguez; Moisés Montaño-Bermúdez

    2012-01-01

    El objetivo fue estimar los componentes de (co)varianza, heredabilidades y correlaciones genéticas y fenotípicas para peso al año (YW), circunferencia escrotal (SC) y talla (FS) en toros jóvenes Simmental y Simbrah de México. Todas las características se ajustaron a 305 días acorde a los lineamientos descritos por la Federación para el Mejoramiento Genético de los Bovinos de Carne (BIF). El archivo final de datos incluyó 1,949 registros Simmental y 1,259 Simbrah. Para estimar los compones de ...

  11. AcEST: DK945247 [AcEST

    Lifescience Database Archive (English)

    Full Text Available 6. 5' end sequence. DK945247 CL259Contig1 Show DK945247 Clone id YMU02A01NGRL0008_L06 Library YMU02 Length 7...63 Definition Adiantum capillus-veneris mRNA. clone: YMU02A01NGRL0008_L06. 5' end sequence. Accession DK945247...s. 25:3389-3402. Query= DK945247|Adiantum capillus-veneris mRNA, clone: YMU02A01NGRL0008_L06, 5' (736 letter...atabase search programs, Nucleic Acids Res. 25:3389-3402. Query= DK945247|Adiantum capillus-veneris mRNA, cl

  12. Phenolic Compounds and Antioxidant Activity of Juices from Ten Iranian Pomegranate Cultivars Depend on Extraction

    OpenAIRE

    Hamidreza Akhavan; Mohsen Barzegar; Helmut Weidlich; Zimmermann, Benno F.

    2015-01-01

    Phenolic compounds and antioxidant activities of ten juices from arils and whole pomegranate cultivars grown in Iran were studied. Phenolic contents and antioxidant activities of juices from whole pomegranate fruit were significantly higher than juices from pomegranate arils, but the variety has a greater influence than the processing method. The main phenolics in the studied juices were punicalagin A (5.40–285 mg/L), punicalagin B (25.9–884 mg/L), and ellagic acid (17.4–928 mg/L). The major ...

  13. American Neutrality in The 20th Century: The Impossible Dream

    Science.gov (United States)

    1995-01-01

    Digest oflnternationalLaw 11, 180; Robert W. Tucker, ILS XLX (sic) (1955), 197, 199n, 258-259. See also Hans Kelsen , ILS XLIX (1954), 157 for a summary...the Modem System of International Law," Recueil des Cours 80 (1952), i:482; also quoted at Whiteman, 11, 150; see also Hans Kelsen , ILS XLIX (1954...N A T I O N A L S T R A T E G I C STUDIES [] Director: Hans A. Birmendijk Publications Directorate & NDU Press [] Fort Lesley I. McNair

  14. PREPARATION OF MONODISPERSE CROSSLINKED POLYMER MICROSPHERES HAVING CHLOROMETHYL GROUP BY DISTILLATION-PRECIPITATION POLYMERIZATION

    Institute of Scientific and Technical Information of China (English)

    Shu-Feng Li; Xin-Lin Yang; Wen-Qiang Huang

    2005-01-01

    Monodisperse crosslinked poly(chloromethylstyrene-co-divinylbenzene) (poly(CMSt-co-DVB)) microspheres were prepared by distillation-precipitation copolymerization of chloromethylstyrene (CMSt) and divinylbenzene (DVB) in neat acetonitrile. The polymer particles had clean surfaces due to the absence of any added stabilizer. The size of the particles ranges from 2.59 μm to 3.19 μm and with mono-dispersity around 1.002-1.014. The effects of monomer feed in copolymerization on the microsphere formation were described. The polymer microspheres were characterized by SEM and chlorinity elemental analysis.

  15. Functionality of a bacillus cereus biological agent in response to physiological variables encountered in cyprinus carpio aquaculture

    CSIR Research Space (South Africa)

    Lalloo, R

    2008-05-01

    Full Text Available (2000) The use and selection of probiotic bacteria for 14 use in the culture of larval aquatic organisms. Aquaculture 191:259-270 15 Gross A, Nemirovsky A, Zilberg D, Khaimov A, Brenner A, Snir E, Ronen Z, Nejidat A 16 (2003) Soil nitrifying... Mechanisms of Disease 20 Suppresion. Phytopathology 92:976-985 21 Hong HA, Duc LH, Cutting SM (2005) The use of bacterial spore formers as probiotics. 22 FEMS Microbiol Rev 29:813-835 23 Irianto A, Austin B (2002) Probiotics in Aquaculture. J. Fish Dis...

  16. Are larger effect sizes in experimental studies good predictors of higher citation rates?

    DEFF Research Database (Denmark)

    Schneider, Jesper Wiborg; Henriksen, Dorte

    2013-01-01

    Effect sizes are perhaps the most important quantitative information in statistical inferential studies. Recently, the hypothesis that rational citation behaviour in general ought to give credit to studies that successfully apply a treatment and detect greater effects, resulting in such studies...... areas and with a more credible model selection procedure. Using meta-analyses, we identify comparable individual experimental studies (n=259) from five different research specialties. Effect sizes are compared to the citation rates of the individual studies and impact factors for the journals where...

  17. Drug: D01007 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01007 Drug Propiverine hydrochloride (JP16); Bup-4 (TN); Mictonorm (TN) C23H29NO3.... HCl 403.1914 403.9422 D01007.gif Parasympatholytic Therapeutic category: 2590 ATC code: G04BD06 muscarinic ...2 Agents affecting individual organs 25 Urogenital and anal organ agents 259 Miscellaneous 2590 Miscellaneous D0100...rinary antispasmodics G04BD06 Propiverine D01007 Propiverine hydrochloride (JP16) Target-based classificatio...holinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133] Propiverine [ATC:G04BD06] D0100

  18. The Effect of Velocity on the Sliding Behaviors of Copper Alloys

    Science.gov (United States)

    1982-11-01

    161 (1981). 1 There has been little work reported on the effect of sliding velocity on metal transfer. Rabinowicz and Tabor 8 studied the pickup of...pe.-A o.a Metallic Weru," Proc. Royal Soc. (London) 259, p. 228 (1960). 8 Rabinowicz , E. and Tabor, D., "MIetallic Transfer Retween Sliding Metals...used in the present study. Their properties are given in Table I. "l1 Carignan, F. J. and Rabinowicz , E., "Friction and Wear at High Slidiog Speeds

  19. CLINICAL STATISTICAL STUDIES ON HEMATURIA IN OUTPATIENTS

    OpenAIRE

    青木, 正治; 熊本, 悦明

    1982-01-01

    Clinical statistical studies on hematuria were performed in outpatients who were seen at our Department, during the 7-year period from 1974 through 1980. Of the 11,574 outpatients studied, the total number of outpatients with hematuria 1,705; macroscopic hematuria was found in 446 cases (3.9%) and microscopic hematuria was in 1,259 cases (10.9%). The most frequent cause of macroscopic hematuria was malignant urinary tumors and that of microscopic hematuria was urinary tract infections. Macros...

  20. Photoluminescence Enhancement in Nanotextured Fluorescent SiC Passivated by Atomic Layer Deposited Al2O3 Films

    DEFF Research Database (Denmark)

    Lu, Weifang; Ou, Yiyu; Jokubavicius, Valdas

    2016-01-01

    The influence of thickness of atomic layer deposited Al2O3 films on nano-textured fluorescent 6H-SiC passivation is investigated. The passivation effect on the light emission has been characterized by photoluminescence and time-resolved photoluminescence at room temperature. The results show...... that 20nm thickness of Al2O3 layer is favorable to observe a large photoluminescence enhancement (25.9%) and long carrier lifetime (0.86ms). This is a strong indication for an interface hydrogenation that takes place during post-thermal annealing. These results show that an Al2O3 layer could serve...

  1. A ponderosa pine natural area reveals its secrets

    Science.gov (United States)

    Allen, Craig D.

    1998-01-01

    Monument Canyon Research Natural Area preserves an unlogged 259- hectare stand of old-growth ponderosa pine in the Jemez Mountains of New Mexico. This preserve, established in 1932, is the oldest research natural area in the state. This two-tiered forest displays an old-growth density of 100 stems per hectare (Muldavin et al. 1995), with an understory thicket of stagnant saplings and poles that raises the total stand density to an average of 5,954 stems per hectare, with concentrations as high as 21,617 stems per hectare (Fig. 1).

  2. Aspectos reprodutivos do camarão de água doce Macrobrachium potiuna (Müller (Crustacea, Decapoda, Palaemonidae na Serra do Piloto, Mangaratiba, Rio de Janeiro, Brasil Reproductive aspects of freshwater shrimp Macrobrachium potiuna (Müller (Crustacea, Decapoda, Palaemonidade in Serra do Piloto, Mangaratiba, Rio de Janeiro, Brazil

    Directory of Open Access Journals (Sweden)

    Luciana dos Santos Antunes

    2004-06-01

    Full Text Available Exemplares de Macrobrachium potiuna (Müller, 1880 foram coletados mensalmente de julho/2001 a junho/2002. No laboratório os camarões foram separados por sexo e mensurados. Fêmeas ovígeras foram separadas e seus ovos contados e mensurados. Foram capturados um total de 1162 indivíduos, dos quais 50% eram fêmeas, 47% machos e 3% juvenis. O período reprodutivo ocorreu durante a primavera-verão. Fêmeas ovígeras apresentaram comprimento total variando de 25,9 a 40,3 mm. A fecundidade média foi de 24,0 ± 9,0 ovos. A primeira maturação sexual ocorreu aos 25,9 mm de comprimento total. As dimensões médias dos ovos foram iguais a 1,56 e 2,08 mm para os eixos menor e maior, respectivamente, durante o estágio inicial de desenvolvimento embrionário e 1,70 e 2,46 mm, respectivamente, para os eixos menor e maior durante o estágio final de desenvolvimento.Samples of Macrobrachium potiuna (Müller, 1880 were collected monthly from July/2001 to June/2002. At the laboratory, shrimps were separated by sex and measured. The ovigerous females were separated and theirs eggs measured and counted. A total of 1162 shrimps were collected, 50% was females, 47% was males and 3% juveniles. The reproductive period occurred during the spring-summer. The ovigerous female showed total length from 25.9 to 40.3 mm. The mean fecundity was 24,0 ± 9,0 eggs. The first sexual maturation occurred at 25.9 mm total length. The eggs showed means dimensions from 1.56 and 2.08 mm, respectively, for the short and the long axis during the initial stage of development and from 1.70 and 1.89 mm, respectively, for the short and long axis during the final stage of development.

  3. Poor performance of BACTEC NR 730 blood culture system in early detection of Neisseria meningitidis.

    OpenAIRE

    1989-01-01

    During an 8-month period at Children's Hospital, Oakland, Calif., a 9% rate for positive blood culture for children with Neisseria meningitidis meningitis was identified. The blood culture system used in each case was the BACTEC NR 730. This rate seemed significantly lower than previous rates (33 to 55%) (P.R. Dodge and M.N. Swartz, N. Engl. J. Med. 272:1003-1010, 1965; A.L. Hoyne and R.H. Brown, Ann. Intern. Med. 28:248-259, 1948; S. Levin and M.B. Painter, Ann. Intern. Med. 64:1049-1057, 19...

  4. Ionic Precursors of Soot - A Combined Experimental-Theoretical Approach

    Science.gov (United States)

    1988-06-01

    1984. 85. Dannacher, J., Helbronner, E., Stadelmann , J.-P. and Vogt, J. Helvetica Chimica Acta, Vol. 62, p. 2186, 1979. 86. Baer, T., Willett, G. D...104-8, 1979. 125. Bombach, R., Dannacher, J., and Stadelmann , JP., J. Am. Chem. Soc., Vol. 105, pp. 4205-11, 1983. 126. Bombach, R., Dannacher, J...and Stadelmann , JP., Chem. Phys. Lett., Vol. 95, pp. 259-61, 1983. 127. Jackson, J-A. A., Diss. Abstr. Int. B, Vol. 38, p. 2691, 1977. 128. Shen, J

  5. Using Exenatide Twice Daily or Insulin in Clinical Practice

    DEFF Research Database (Denmark)

    Mathieu, Chantal; Ostenson, Claes-Göran; Matthaei, Stephan;

    2013-01-01

    were recruited; 1,114 patients in the exenatide BID cohort and 1,274 patients in the insulin cohort were eligible for the 24-month analysis. During the study, 42.2% and 36.0% of patients from each cohort, respectively, had a significant treatment change. By 24 months, improved mean glycated hemoglobin...... BID cohort and 36.8% of the insulin cohort; 25.9% of the exenatide BID cohort and 10.0% of the insulin cohort had met the secondary endpoint of glycated hemoglobin

  6. Ultrafast Molecular Imaging by Laser Induced Electron Diffraction

    CERN Document Server

    Peters, Michel; Cornaggia, Christian; Saugout, Sébastien; Charron, Eric; Keller, Arne; Atabek, Osman

    2010-01-01

    We address the feasibility of imaging geometric and orbital structure of a polyatomic molecule on an attosecond time-scale using the Laser Induced Electron Diffraction, LIED, technique [T. Zuo \\textit{et al.}, Chem. Phys. Lett. \\textbf{259}, 313 (1996)]. We present numerical results obtained for the CO$_2$ molecule using a single active electron model. The molecular geometry (bond-lengths) is determined within 3% of accuracy from a diffraction pattern which also reflects the nodal properties of the initial molecular orbital. Robustness of the structure determination is discussed with respect to vibrational and rotational motions with a complete interpretation of the laser-induced mechanisms.

  7. 4-Bromoselenoanisole

    Directory of Open Access Journals (Sweden)

    Henning Osholm Sørensen

    2009-07-01

    Full Text Available The title compound, 1-bromo-4-methylselenobenzene, C7H7BrSe, was prepared by methylation of 4-bromoselenophenolate with methyl iodide, and crystals suitable for structure determination were obtained by sublimation. The molecule is essentially planar; the Se—Me bond is rotated by only 2.59 (19° out of the least-squares plane of the benzene ring. The most pronounced intermolecular interactions are two hydrogen bonds of the type C—H...π, which determine a herring-bone pattern in the crystal packing.

  8. Luminaolide, a novel metamorphosis-enhancing macrodiolide for scleractinian coral larvae from crustose coralline algae.

    Science.gov (United States)

    Kitamura, Makoto; Schupp, Peter J; Nakano, Yoshikatsu; Uemura, Daisuke

    2009-11-25

    A new metamorphosis-enhancing macrodiolide, luminaolide (1), was isolated from the crustose coralline algae (CCA) Hydrolithon reinboldii. Its structure was determined by spectroscopic analysis. A fraction (1.30 mug/mL) eluted with 80% aqueous MeOH by ODS gel column chromatography of the same CCA extract induced larval metamorphosis (25.9 +/- 7.4%) against Leptastrea purpurea, and its metamorphosis-inducing activity was further enhanced to 92.6 +/- 2.9% with the addition of 1 (25.6 ng/mL).

  9. Beaked Whale Strandings and Naval Exercises

    Science.gov (United States)

    2009-01-01

    1892). Observations anatomiques sur l’Hyperoodon rostratus Lilljeborg. Annales de Sciences Naturelles, Zoologie, 13(7), 259-320. Brasil , L. (1909...Department of the Navy (U.S. DoN). (2002a). Marine resources assessment for the Gulf of Mexico operating area. Prepared by Geo-Marine, Inc., Plano, TX...Zealand n/a Oliver, 1922 29 Aug 1891 Ha 5 France n/a Jouan, 1891; Bouvier, 1892; Brasil , 1909d 16 June 1903 Bb 2 US (AK) n/a True, 1910 20 Sept 1927 Ha 4

  10. Mucinous gastric hyperplasia in a colony of rhesus monkeys (Macaca mulatta) induced by polychlorinated biphenyl (Aroclor 1254)

    Energy Technology Data Exchange (ETDEWEB)

    Geistfeld, J.G.; Bond, M.G.; Bullock, B.C.; Varian, M.C.

    1982-02-01

    Since 1971, 45 of 259 male rhesus monkeys housed in a primate building have died of a chronic and progressive disease characterized by diarrhea, dehydration, weakness, gingivitis, emaciation, and alopecia. The principal necropsy finding in these monkeys, and in eight others killed for experimental purposes, was hypertrophic and hyperplastic mucinous gastropathy involving both the mucosa and submucosa. The toxic agent involved was identified as the polychlorinated biphenyl (PCB), Aroclor 1254. The suspected source of the toxic agent was a concrete sealer used during building construction.

  11. Preliminary Identification of Causal Organisms of Rice Wilt%寒地水稻立枯病病原真菌的分离鉴定

    Institute of Scientific and Technical Information of China (English)

    郑雯; 刘立新; 辛惠普

    2002-01-01

    1999~2001年从黑龙江省不同地区832株水稻立枯病病苗样品中分离获得1 318个分离物,经鉴定归属7个属12个种,其中Fusarium oxysporum占19.7%,Fusarium solani占25.9%,Fusarium graminearum占17.1%,Fusarium moniliforme占8.2%,Fusarium semitectum占9.4%,Rhizoctonia solani占16.5%.对分离频率较高的种类进行回接验证,均能引起水稻立枯病.

  12. Drug: D01965 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D01965 Drug Silodosin (JAN/INN); KMD 3213; Rapaflo (TN); Urief (TN) C25H32F3N3O4 49...nal organ agents 259 Miscellaneous 2590 Miscellaneous D01965 Silodosin (JAN/INN) ...04 UROLOGICALS G04C DRUGS USED IN BENIGN PROSTATIC HYPERTROPHY G04CA Alpha-adrenoreceptor antagonists G04CA04 Silodosin D01965 Silodo...ourinary Agents Benign Prostatic Hypertrophy Agents Silodosin D01965 Silodosin (JAN/INN) Target-based classi...eptor [HSA:146 147 148] [KO:K04137 K04136 K04135] Silodosin [ATC:G04CA04] D01965 Silodosin (JAN/INN) CAS: 16

  13. Multi-Scale Microstructure and Mechanical Properties of High Carbon Eutectic Tantalum Carbide Reinforced with Carbon Nanotubes

    Science.gov (United States)

    2012-07-02

    of 5 vol.% of MoSi2 helped in densification up to 98% [29]. Hafnium carbide [22,23] and zirconium carbide [23] powders have been successfully...244–250. [2] O. Khyzhun, J. Alloys Compd. 259 (1997) 47–58. [3] J.G. Choi, Appl. Catal. A 184 (1999) 189–201. [4] R.W. Bartlett, C.W. Smith, J. Appl...Hulbert, A. Anders, J. Andersson, E.J. Lavernia, A.K. Mukherjee, Scripta Mater. 60 (2009) 835–838. [20] F. Monteverde, J. Alloys Compd. 428 (2007

  14. EST Table: FS913761 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS913761 E_FL_fufe_30E02_F_0 10/09/28 79 %/252 aa ref|NP_001040215.1| stathmin [Bom...byx mori] gb|ABD36259.1| stathmin [Bombyx mori] 10/09/12 51 %/192 aa FBpp0078829|stai-PA 10/08/29 n.h 10/09/...B18507-PA 10/09/10 49 %/259 aa gi|91083957|ref|XP_975021.1| PREDICTED: similar to stathmin [Tribolium castaneum] FS915193 fufe ...

  15. Three-phase tectonic evolution of the Andaman backarc basin

    Digital Repository Service at National Institute of Oceanography (India)

    KameshRaju, K.A.

    . Lett ., 2001, 185 , 253 ? 264. 13. Parson, L. M. and Hawkin s, J. W., Two - stage ridge propagation and the geological history of the Lau backarc basin. In Proc. Ocean Drill. Pr o gramme Sci. Results , 1995, vol. 135, pp. 819 ? 828. 14...: a new seismotectonic i nsight. Earth Planet. Sci. Lett ., 2005, 229 , 259 ? 271. 18. Curray, J. R., Tectonics and history of the Andaman Sea region. J. Asian Earth Sci. , 2005, 25 , 187 ? 232. 19. Smith, W. H. F. and Sandwell, D. T...

  16. Impact of benthic disturbance on megafauna in Central Indian Basin

    Digital Repository Service at National Institute of Oceanography (India)

    Rodrigues, N.; Sharma, R.; Nath, B.N.

    .PhilosophicalTransactionsoftheRoyalSocietyofLondonA 307, 377–403. Amos, A.F., Roels, O.A., Garside, C., Malone, T.C., Paul, A.Z., 1977. Environmental aspects of nodule mining. In: Galsby, G.P. (Ed.), Marine Manganese Deposits. Elsevier Oceanography Series 15, Elsevier, Amsterdam, pp. 523. Billet, D.S.M...., 1986. The rise and fall of the sea cucumber. New Scientist 19 (1500), 48–51. Billet, D.S.M., 1991. Deep-sea holothurians. Oceanography and Marine BiologyFAnnual Review 29, 259–317. Bischoff,J.L.,Piper, D.Z.(Eds.), 1979.Marine...

  17. An extended doubly-adaptive quadrature method based on the combination of the Ninomiya and the FLR schemes

    Science.gov (United States)

    Hasegawa, Takemitsu; Hibino, Susumu; Hosoda, Yohsuke; Ninomiya, Ichizo

    2007-08-01

    An improvement is made to an automatic quadrature due to Ninomiya (J. Inf. Process. 3:162?170, 1980) of adaptive type based on the Newton?Cotes rule by incorporating a doubly-adaptive algorithm due to Favati, Lotti and Romani (ACM Trans. Math. Softw. 17:207?217, 1991; ACM Trans. Math. Softw. 17:218?232, 1991). We compare the present method in performance with some others by using various test problems including Kahaner?s ones (Computation of numerical quadrature formulas. In: Rice, J.R. (ed.) Mathematical Software, 229?259. Academic, Orlando, FL, 1971).

  18. Libros colombianos raros y curiosos: octubre de 1963

    Directory of Open Access Journals (Sweden)

    Ignacio Rodríguez Guerrero

    1963-10-01

    Full Text Available NAVIA MIGUEL (1872-1913. Por Honor de Colombia. Refutación del libro INRI.-Colección de artículos y documentos relativos a la candidatura del señor General Rafael Reyes.-Bogotá, Imprenta Nacional, 1905. XXX-259 págs.  No son abundantes los datos que hemos logrado averiguar con referencia al autor de este libro. Sabemos únicamente, a través del Diccionario Biográfico y Genealógico del antiguo Departamento del Cauca, de Gustavo Arboleda, que nació en Cali el 4 de mayo de 1872.

  19. Prediction of acute in vivo toxicity of some amine and amide drugs to rats by multiple linear regression, partial least squares and an artificial neural network.

    Science.gov (United States)

    Mahani, Mohamad Khayatzadeh; Chaloosi, Marzieh; Maragheh, Mohamad Ghanadi; Khanchi, Ali Reza; Afzali, Daryoush

    2007-09-01

    The oral acute in vivo toxicity of 32 amine and amide drugs was related to their structural-dependent properties. Genetic algorithm-partial least-squares and stepwise variable selection was applied to select of meaningful descriptors. Multiple linear regression (MLR), artificial neural network (ANN) and partial least square (PLS) models were created with selected descriptors. The predictive ability of all three models was evaluated and compared on a set of five drugs, which were not used in modeling steps. Average errors of 0.168, 0.169 and 0.259 were obtained for MLR, ANN and PLS, respectively.

  20. Air-Sea Interaction Studies of the Indian and Pacific Oceans

    Science.gov (United States)

    2014-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. Air-Sea Interaction Studies of the Indian and Pacific...2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Air-Sea Interaction Studies of the Indian and Pacific Oceans...applied to ship- generated waves in the 1989 Loch Linnhe experiment, J. Geophys. Res., 98, 10,259-10,269. Wikipedia, 2013: “Crow’s Nest”, http://en.wikipedia.org/wiki/ Crow %27s_nest, Referenced May 30, 2013.