WorldWideScience

Sample records for du futur applications

  1. application du Global Entrepreneurship Monitor

    International Development Research Centre (IDRC) Digital Library (Canada)

    Promotion de la recherche sur l'entrepreneuriat en Asie du Sud-Est - application du Global Entrepreneurship Monitor ... Indonesia, Malaysia, Philippines, Viet Nam ... IDRC is pleased to announce a new funding opportunity aimed at fostering effective, long-term climate action to reduce social inequality, promote greater ...

  2. Sådan kan du bruge optioner og futures

    DEFF Research Database (Denmark)

    Kohl, Niklas

    2017-01-01

    Masterclass. Har du brug for at forsikre værdierne i din portefølje i en periode, hvor du forventer stor uro på finansmarkederne, kan du gøre det med optioner eller futures. Her kan du læse om de forskellige typer – og om de muligheder de giver dig.......Masterclass. Har du brug for at forsikre værdierne i din portefølje i en periode, hvor du forventer stor uro på finansmarkederne, kan du gøre det med optioner eller futures. Her kan du læse om de forskellige typer – og om de muligheder de giver dig....

  3. Une force venant du futur chercherait à saboter l'expérience du LHC...

    CERN Multimedia

    Scappaticci, Bruno

    2009-01-01

    "A quelques jours de la reprise de l'expérience du LHC, on ne parle plus de la menace d'un trou noir, mais deux physicines souteinnent aujourd'hui une tout autres hypothèse: la nature, depuis le futur, va continuer de contrarier les travaux du Cern, afin d'éviter à l'Homme de mettre le doigt là où il ne faut pas..." (1.5 pages)

  4. simulation du climat futur et des rendements agricoles en region

    African Journals Online (AJOL)

    ACSS

    2017, African Crop Science Society. African Crop Science Journal by African Crop Science Society is licensed under a Creative Commons Attribution 3.0 Uganda License. Based on a work at www.ajol.info/ and www.bioline.org.br/cs. DOI: http://dx.doi.org/10.4314/acsj.v25i4.2. SIMULATION DU CLIMAT FUTUR ET DES ...

  5. Future systems and strategies; Systemes du futur et strategies

    Energy Technology Data Exchange (ETDEWEB)

    David, S. [Institut de Physique Nucleaire CNRS/IN2P3, Universite Paris XI Orsay (France)

    2007-07-01

    This lecture deals with the different nuclear technologies which could be developed in the future. We present some physical aspects of future fission-based nuclear reactors. First, we give an overview of the energy problematic in the coming century, in order to define what could be requested from nuclear power. We describe the present reactors, based on the fission of U-235. They require around 200 tons of natural uranium to fission only 1 ton of fissile material. Regarding the estimated uranium resources, the question of the transition towards breeding reactors is discussed. Some simple calculations show that breeding of plutonium can be reached only with a fast neutron spectrum. For the thorium cycle, breeding with thermal neutrons requires the use of molten salt reactors. These two fuel cycles are compared in term of fissile inventory, ability of deployment, and R and D efforts. As a conclusion, we discuss some questions which showed up during the Joliot-Curie school, concerning the different strategies which could be chosen in the coming years. (author)

  6. Systems of the future; Les systemes du futur

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-01-15

    The world population growth will impact largely on the energy and electric power demand in the future. Facing the decrease of the hydrocarbons reserves, the international community decided to work together to develop a new generation of nuclear systems. In this context, coordinated researches are realized first with a short dated objective on the development of innovations for PWR type reactors and second with a middle dated on the development of new systems in an international framework (essentially Generation IV). Theses research programs are presented below. The first part is devoted to the different generation of reactors (I to IV) and to the third generation; the second part deals with the international framework of the researches, the french strategy and the european dimension. (A.L.B.)

  7. Computer Applications in Counselor Education: Developing Cultural Competencies Through Online Collaboration of Future School Counselors / L’informatique dans l’éducation des orienteurs : le développement du savoir-faire culturel par la collaboration en

    Directory of Open Access Journals (Sweden)

    Vessela Ilieva

    2012-07-01

    Full Text Available This study examined the applications of computer-mediated student collaboration in a graduate multicultural counseling course. The course work included a reflective cultural competency building assignment that utilized online communication and collaboration using a wiki to extend and improve students’ multicultural counseling and social justice advocacy skills. The online assignment design was aligned with the current call for utilizing technology in the counseling profession. It further considered the needs of the future counselors, the current levels of exposure to and experience with available technology of the class members, and the opportunities for utilization of a variety of online-based tools to extend in-class and out-of-class discussions. Students’ response to this new form of class work and communication confirmed the potential of the online component to other aspects of counselor preparation, and the data analysis showed that the computer-mediated assignment was a valuable addition to developing students’ skills as multiculturally competent professionals. Cette étude a examiné les applications de la collaboration entre étudiants par l’entremise de l’informatique dans le cadre d’un cours d’études supérieures sur l’orientation en contexte multiculturel. Les travaux du cours comprenaient un travail de réflexion pour renforcer le savoir-faire culturel grâce à la communication et à la collaboration en ligne, en utilisant un wiki pour accroître et améliorer les aptitudes des étudiants en orientation en contexte multiculturel et en défense de la justice sociale. La conception du travail en ligne s’alignait sur la tendance actuelle pour une utilisation accrue de la technologie dans le métier de conseiller en orientation. On y tenait également compte des besoins des futurs conseillers, de leur degré d’exposition à la technologie et de leur expérience avec celle-ci, ainsi que des occasions pour l

  8. Future applications of heterostructures

    Science.gov (United States)

    König, Ulf

    1996-01-01

    In this review the status and future of heterostructure devices is discussed. The author concentrates on III/V and Si/SiGe. Performance and applications are folded to the data and expectations of the micro- and opto-electronic market and to the traditional Si-mainstream. New trends, i.e. the SIA-roadmap, are checked how heterodevices can fit in. Only the most attractive candidates for applications are considered, i.e. the heterobipolar-, the hetero field effect-transistors, the resonant tunnel diode and to a less extent, some optoelectronic devices. Considered figures of merit are frequencies, transconductance, noise at high and low frequencies, threshold voltage, power delay, threshold current and quantum efficiencies. It is pointed out how to optimize those by material and design. Extrapolations to the future potential of heterodevices are made, just taking the claimed scaling of lateral dimensions into consideration. Field of applications are presented, where heterodevices offer exclusive qualities, i.e. high frequency transmission and sensors, and new mixed systems. In the case of logic the trend goes to nanoscaled devices and ICs targeting nanoelectronics beyond traditional electronics. Heterostructure layers allow a vertical nanoscaling and thus give an additional degree of freedom for designing and optimation. It is an attractive challenge for scientists and engineers to solve the related technological problems like thin, low thermal budget oxides, like defect free buffer layers etc. Special attention is put on Si/SiGe, which is now on an upswing in electronics and photonics.

  9. ESTIMATION DU MODELE LINEAIRE GENERALISE ET APPLICATION

    Directory of Open Access Journals (Sweden)

    Malika CHIKHI

    2012-06-01

    Full Text Available Cet article présente  le modèle linéaire généralisé englobant les  techniques de modélisation telles que la régression linéaire, la régression logistique, la régression  log linéaire et la régression  de Poisson . On Commence par la présentation des modèles  des lois exponentielles pour ensuite estimer les paramètres du modèle par la méthode du maximum de vraisemblance. Par la suite on teste les coefficients du modèle pour voir leurs significations et leurs intervalles de confiances, en utilisant le test de Wald qui porte sur la signification  de la vraie valeur du paramètre  basé sur l'estimation de l'échantillon.

  10. Recent and future developments at the Regie du gaz naturel

    International Nuclear Information System (INIS)

    Giroux, J.

    1995-01-01

    The history of the Quebec Regie du gaz naturel, dating back to 1932, and its role in distributing natural gas in Quebec was described. Among more recent developments construction of a natural gas distribution system on the south shore of Quebec City was discussed. Unlinked mini-systems were built in St-Romuald and Levis. Gas was delivered by truck until an underwater crossing was completed. The federal-provincial infrastructures program was also summarized. The most important ruling by the Regie was the D-94-19 decision on GMi's supply policy and the concept of u mbrella buy-sell . Although this policy was originally approved by the Regie, after consideration of all factors, it was decided that this system was not in line with the deregulation trend and that buyers and sellers could do without GMi's intrusion in their contractual agreements. Issues to be addressed by the Regie in the coming months included transportation service, unbundling, cost allocation and rate of return adjustments mechanism in regards to the recent National Energy Board (NEB) decision on the subject, and separation of (LDC) distribution activities from LDC sales

  11. Coronagraphy at Pic du Midi: Present state and future projects

    Science.gov (United States)

    Koechlin, L.

    2012-12-01

    The Pic du Midi coronagraph (CLIMSO) is a group of four instruments in parallel, taking images of the whole solar photosphere and low corona. It provides series of 2048*2048 pixels images taken nominally at 1 minute time intervals, all year long, weather permitting. A team of ≃q 60 persons, by groups of 2 or 3 each week, operate the instruments. Their work is programmed in collaboration with Institut de Recherches en astrophysique et planétologie (IRAP) of Observatoire Midi Pyrénées (OMP), and with Programme National Soleil Terre (PNST). The four instruments of CLIMSO (L1, C1, L2 and C2) collect images of the Sun as following: 1) L1 : photosphere in H-α (656.28 nm) ; 2) L2 : photosphere in Ca-II (393.37 nm) ; 3) C1 : prominences in H-α ; 4) C2 : prominences in He-I (1083.0 nm). The data taken are stored in fits format images and mpeg films. They are available publicly on data bases such as BASS 2000 Meudon ({http://bass2000.obspm.fr/home.php?lang=en} and BASS2000 Tarbes ({http://bass2000.bagn.obs-mip.fr/base/sun/index.php}). Several solar studies are carried in relation with these data. In addition to the raw fits images, new images will soon be sent to the data bases: they will be calibrated in solar surface emittance, expressed in W/m^2/nm/steradian. Series of mpeg films for each day are presented in superposed color layers, so as to visualize the multispectral information better. New instrumental developments are planned for the next years and already financed. They will use spectropolarimetry to measure the magnetic field and radial velocities in the photosphere and corona. The data will cover the entire solar disc and have a sample rate of one map per minute.

  12. L'application du droit penal islamique dans le Nord-Nigeria

    NARCIS (Netherlands)

    Dekker, A.J.; Ostien, P.

    2009-01-01

    Cet article etudie l'application du code penal islamique dans le Nord-Nigeria ainsi que les programmes de mise en oeuvre de la charia lances dans douze Etats du Nord en 1999-2000. Les nouvelles lois du Code penal islamique promulguees par les douze Etats pratiquant la charia sont detaillees pour

  13. Applications de l'optique diffractive dans le domaine du traitement de l'information

    OpenAIRE

    Roose, Stéphane

    1996-01-01

    Après une introduction résumant l'historique du mariage entre l'optique diffractive et le traitement de l'information, la synthèse d'optiques diffractives sera discuté, suivie par des exemples d'applications d'optique diffractive dans le domaine du traitement de l'information.

  14. Industrial applications of laser; Applications industrielles du laser

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    This technical dossier is a result of a collaboration between the CFE and the Power Laser club with the sustain of the French Ministry of Industry. It presents a catalogue of the industrial applications of the laser technology in France with about 80 technical files about companies using this technology in various domains such as: weapons industry, civil engineering, confection, automotive equipments, electrical equipments, medical applications, instrumentation, tools, sheet iron and steel plate industry etc.. (J.S.)

  15. Advanced Ceramic Materials for Future Aerospace Applications

    Science.gov (United States)

    Misra, Ajay

    2015-01-01

    With growing trend toward higher temperature capabilities, lightweight, and multifunctionality, significant advances in ceramic matrix composites (CMCs) will be required for future aerospace applications. The presentation will provide an overview of material requirements for future aerospace missions, and the role of ceramics and CMCs in meeting those requirements. Aerospace applications will include gas turbine engines, aircraft structure, hypersonic and access to space vehicles, space power and propulsion, and space communication.

  16. Future Health Applications of Genomics

    Science.gov (United States)

    McBride, Colleen M.; Bowen, Deborah; Brody, Lawrence C.; Condit, Celeste M.; Croyle, Robert T.; Gwinn, Marta; Khoury, Muin J.; Koehly, Laura M.; Korf, Bruce R.; Marteau, Theresa M.; McLeroy, Kenneth; Patrick, Kevin; Valente, Thomas W.

    2014-01-01

    Despite the quickening momentum of genomic discovery, the communication, behavioral, and social sciences research needed for translating this discovery into public health applications has lagged behind. The National Human Genome Research Institute held a 2-day workshop in October 2008 convening an interdisciplinary group of scientists to recommend forward-looking priorities for translational research. This research agenda would be designed to redress the top three risk factors (tobacco use, poor diet, and physical inactivity) that contribute to the four major chronic diseases (heart disease, type 2 diabetes, lung disease, and many cancers) and account for half of all deaths worldwide. Three priority research areas were identified: (1) improving the public’s genetic literacy in order to enhance consumer skills; (2) gauging whether genomic information improves risk communication and adoption of healthier behaviors more than current approaches; and (3) exploring whether genomic discovery in concert with emerging technologies can elucidate new behavioral intervention targets. Important crosscutting themes also were identified, including the need to: (1) anticipate directions of genomic discovery; (2) take an agnostic scientific perspective in framing research questions asking whether genomic discovery adds value to other health promotion efforts; and (3) consider multiple levels of influence and systems that contribute to important public health problems. The priorities and themes offer a framework for a variety of stakeholders, including those who develop priorities for research funding, interdisciplinary teams engaged in genomics research, and policymakers grappling with how to use the products born of genomics research to address public health challenges. PMID:20409503

  17. Les futurs possibles du dopage representés [sic] à l'aide de la cartographie de l'information

    OpenAIRE

    Gaffuri, Alessandra; Gauthier, Thomas

    2014-01-01

    Le but de ce travail est de comprendre quels seront les futurs possibles du dopage en utilisant la cartographie de l’information. Le travail comporte une recherche et une analyse de 150 articles de presse traitant de la pratique du dopage. Les informations répertoriées sur Internet seront représentées à l’aide de la cartographie de l’information. La visualisation sous forme de cartes permettra d’illustrer les principales tendances concernant le phénomène du dopage. Les quatre cartographies on...

  18. Les bourses du CRDI appuient les futurs chefs de file dans le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Par exemple, une étude propose un plan de gestion foncière visant à limiter les risques que posent les ouragans pour les forêts du Nicaragua, où un ouragan a détruit 400 000 hectares de forêt en 2007. Au Kenya, une étude a révélé que les agriculteurs modifient déjà leurs pratiques pour s'adapter aux changements ...

  19. Adjustable Speed Drives - Future Challenges and Applications

    DEFF Research Database (Denmark)

    Blaabjerg, Frede; Thoegersen, Paul

    2004-01-01

    are specified. Further on power architectures and motor types are discussed in a short term and long-term view. Possible drivers of the future development are identified, and the concept of an ?Electronic Motor? is discussed. A number of applications are presented where variable speed is attractive.......The main trends within Adjustable Drives in industrial and appliance applications for the next decade are discussed based on the newest developments seen on the market and a few historical trends. Different drive configurations are presented and the general demands to adjustable speed drives...

  20. Perspective d'avenir du marché de l'hydrogène Future Outlook of the Hydrogen Market

    Directory of Open Access Journals (Sweden)

    Ozmen S.

    2006-11-01

    Full Text Available L'hydrogène qui avait été jusqu'à présent produit à partir des hydrocarbures pour des usages chimiques devra dans les années futures, trouver un marché nouveau qui sera foncfion du développement des centrales nucléaires. Par utilisation de l'énergie électrique ou thermique disponible aux heures creuses, la décomposition de l'eau par voie électrolytique ou thermique (cycle d'oxydoréduction produirait l'hydrogène; gaz stockable et transportable. En plus de la consommation de l'hydrogène pour usage chimique-fabrication du méthanol, de l'ammoniac, hydrotraitement des fractions pétrolières, la métallurgie,... dont l'importance va croître, on envisage l'emploi de l'hydrogène comme véhicule d'énergie. Up to now, hydrogen has been produced from hydrocarbons for chemical uses. In the future, if will have to find a new market for itself which will depend on the development of nucleor power plants. Through the use of electric or thermal energy available during off-peak hours, water decomposition by electrolic or thermal methods (redox cycle could produce hydrogen, a storable and transportable gas. In addition to hydrogen consumption for chemical uses (manufacturing methanol, ammonia, hydrotreating petroleum fractions, metallurgy, etc. which will become greater, plans are being drawn up to use hydrogen as a vehicle for energy.

  1. Future information communication technology and applications

    CERN Document Server

    Kim, Jung; Sahama, Tony; Yang, Chung-Huang; 2013 International Conference on Future Information & Communication Engineering (ICFICE 2013)

    2013-01-01

    These proceedings are based on the 2013 International Conference on Future Information & Communication Engineering (ICFICE 2013), which will be held at Shenyang in China from June 24-26, 2013. The conference is open to all over the world, and participation from Asia-Pacific region is particularly encouraged. The focus of this conference is on all technical aspects of electronics, information, and communications ICFICE-13 will provide an opportunity for academic and industry professionals to discuss the latest issues and progress in the area of FICE. In addition, the conference will publish high quality papers which are closely related to the various theories and practical applications in FICE. Furthermore, we expect that the conference and its publications will be a trigger for further related research and technology improvements in this important subject.  "This work was supported by the NIPA (National IT Industry Promotion Agency) of Korea Grant funded by the Korean Government (Ministry of Science, ICT...

  2. The graphics future in scientific applications

    International Nuclear Information System (INIS)

    Enderle, G.

    1982-01-01

    Computer graphics methods and tools are being used to a great extent in scientific research. The future development in this area will be influenced both by new hardware developments and by software advances. On the hardware sector, the development of the raster technology will lead to the increased use of colour workstations with more local processing power. Colour hardcopy devices for creating plots, slides, or movies will be available at a lower price than today. The first real 3D-workstations appear on the marketplace. One of the main activities on the software sector is the standardization of computer graphics systems, graphical files, and device interfaces. This will lead to more portable graphical application programs and to a common base for computer graphics education. (orig.)

  3. The future of simulations for space applications

    Science.gov (United States)

    Matsumoto, H.

    Space development has been rapidly increasing and there will be huge investment by business markets for space development and applications such as space factory and Solar Power Station (SPS). In such a situation, we would like to send a warning message regarding the future space simulations. It is widely recognized that space simulation have been contributing to the quantitative understanding of various plasma phenomena occurring in the solarterrestrial environment. In the current century, however, in addition to the conventional contribution to the solar-terrestrial physics, we also have to pay our attention to the application of space simulation for human activities in space. We believe that space simulations can be a a powerful and helpful tool for the understanding the spacecraft-environment interactions occurring in space development and applications. The global influence by exhausted heavy ions from electric propulsion on the plasmasphere can be also analyzed by the combination of MHD and particle simulations. The results obtained in the simulations can provide us very significant and beneficial information so that we can minimize the undesirable effects in space development and applications. 1 Brief history of ISSS and contribution to the space plasma physics Numerical simulation has been largely recognized as a powerful tool in the advance of space plasma physics. The International School for Space Simulation (ISSS) series was set up in order to emphasize such a recognition in the early eighties, on the common initiative of M. Ashour-Abdalla, R. Gendrin, T. Sato and myself. The preceding five ISSS's (in Japan, USA, France, Japan, and Japan again) have greatly contributed to the promotion of and advance of computer simulations as well as the education of students trying to start the simulation study for their own research objectives.

  4. Applications of nuclear physics: Future trends

    International Nuclear Information System (INIS)

    Eichler, R.

    2005-01-01

    Nuclear physics and energy research depends on and advances science and technology outside of the nuclear field. Perhaps the most commonly perceived benefits to society from nuclear and particle physics are those derived from particle beam technology. Charged particle accelerators play an increasing role in applications in industry and medicine. Neutrons produced with a high power proton accelerator in a spallation process are used from basic research, radiography in automotive industry (example fuel cell development) to transmutation of highly radioactive fission products. Production and acceleration of ultra cold neutrons provide intense and almost mono-energetic neutrons to study soft matter. Heavier radioisotopes are used in a wide field ranging from medicine to semiconductor industry (ion implantation for doping or coating technologies). Concrete examples and future trends will be given. Detailed understanding of ion physics at low energy allows the design of compact accelerator mass spectroscopy (close to table top size). The ability to measure concentrations of specific radioactive isotopes even below the natural radioactivity widens the scope of applications from archaeology, climate research to food industry. Such a compact device is close to commercialisation. (author)

  5. Nuclear systems of the future - generation 4. Proposals of strategic orientations for the nuclear systems of the future; Les systemes nucleaires du futur - generation 4. Propositions d'orientations strategiques pour les systemes nucleaires du futur

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Several points, specific to France, must be taken into consideration for the long term strategic choice of future nuclear systems, in particular: taking the best profit of the progress potentialities of water reactors, optimizing the opportunities offered by the renewal of power plants in operation, integrating the consequences and the implementation of a strategy of optimized management of radioactive wastes, and looking for improvements that would make nuclear energy an active contributor to sustainable development. The prospective researches carried out by the CEA and its industrial partners have led to propose a R and D strategy with 3 complementary goals: search for innovations for water reactors, development of fast neutron reactors with closed fuel cycle (sodium fast reactor (SFR), gas fast reactor (GFR)), and development of key-technologies for nuclear hydrogen production (very high temperature reactor (VHTR)). The R and D effort concerns also the subcritical systems devoted to transmutation, the new cycle processes for a global management of actinides, and some other nuclear systems like the molten salt reactors (MSR) and the supercritical water reactors (SCWR). This paper presents the R and D strategy for each technology with its priorities, steps, financial means and collaborations. (J.S.)

  6. The future of the refining industry; L`avenir de l`industrie du raffinage

    Energy Technology Data Exchange (ETDEWEB)

    Favennec, J.P.; Guerard, P.; Freund, E.; Obe, P.; O`Brien, D.; Montanier, J.C.

    1995-12-31

    An analysis of the situation and of the future prospects of the refining industry in Europe is given and compared to the other world areas (USA, south-east Asian). Nowadays, the refining industry imposes to take into account of the environmental constraints, of the products qualities and of the refineries emissions. New possible technologies are described. (O.M.) 21 refs.

  7. Fragmentation des habitats et le devenir des lémuriens du Sud et du Sud-ouest de Madagascar Habitat fragmentation and the future of lemurs in the South and South-west of Madagascar

    Directory of Open Access Journals (Sweden)

    Germain Jules Spiral

    2011-10-01

    Full Text Available Qualifiée jadis d’île verte, Madagascar est aujourd’hui l’une des parties du monde la plus tragiquement érodée par l’action humaine sous toutes ses formes. Depuis l’arrivée de l’Homme sur la grande île, la dégradation progressive des forêts malgaches dont les causes sont nombreuses est à l’origine des conséquences alarmantes qui pèsent non seulement sur la population des lémuriens, mais aussi sur la nation toute entière, la région du Sud et du Sud-ouest en particulier : ce qui ne fait qu’hypothéquer le développement du pays. A cet égard, des mesures urgentes de protection et de préservation doivent figurer parmi les priorités régionales, voire nationales, pour réparer au moins partiellement les dégâts constatés et assurer un avenir meilleur aux générations futures.Once called "green island", Madagascar is now one of the most degraded part of the world due to all kinds of human activities. Since men arrived on the island, progressive degradation of forests became more and more alarming for the survival of lemur populations as well as the whole nation, particularly in the southern and south western regions leading to the handicap of the development of the country. Therefore, urgent rules of conservation and preservation must be undertaken as priority in the region or even in the country in order to limit at least partially the observed degradations and insure a better future for the next generations.

  8. Les bourses du CRDI appuient les futurs chefs de file dans le ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    13 mai 2015 ... Cependant, les recherches sont limitées dans ce domaine émergent, et il n'existe pas assez de données probantes pour éclairer les politiques et les pratiques. Le programme Applications novatrices des TIC pour l'atténuation des répercussions des changements climatiques sur les ressources en eau ...

  9. Future scientific applications for high-energy lasers

    Energy Technology Data Exchange (ETDEWEB)

    Lee, R.W. [comp.

    1994-08-01

    This report discusses future applications for high-energy lasers in the areas of astrophysics and space physics; hydrodynamics; material properties; plasma physics; radiation sources; and radiative properties.

  10. Next generation of energy production systems; Lancement pour les systemes du futur

    Energy Technology Data Exchange (ETDEWEB)

    Rouault, J.; Garnier, J.C. [CEA Saclay Dir. de l' Energie Nucleaire DEN, 91 - Gif sur Yvette (France); Carre, F. [CEA Saclay, Dir. du Developpement et de l' Innovation Nucleares - DDIN, 91 - Gif Sur Yvette (France)] [and others

    2003-07-01

    This document gathers the slides that have been presented at the Gedepeon conference. Gedepeon is a research group involving scientists from Cea (French atomic energy commission), CNRS (national center of scientific research), EDF (electricity of France) and Framatome that is devoted to the study of new energy sources and particularly to the study of the future generations of nuclear systems. The contributions have been classed into 9 topics: 1) gas cooled reactors, 2) molten salt reactors (MSBR), 3) the recycling of plutonium and americium, 4) reprocessing of molten salt reactor fuels, 5) behavior of graphite under radiation, 6) metallic materials for molten salt reactors, 7) refractory fuels of gas cooled reactors, 8) the nuclear cycle for the next generations of nuclear systems, and 9) organization of research programs on the new energy sources.

  11. Évaluation de l'application par l'Afrique du Sud d'une taxe d'accise ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Évaluation de l'application par l'Afrique du Sud d'une taxe d'accise sur les boissons sucrées. Les maladies non transmissibles, qui contribuent de façon marquée à la charge de morbidité de l'Afrique du Sud sont largement causées par l'obésité et les maladies associées. La prévalence de l'obésité a augmenté de 30 ...

  12. Applications of nuclear energy in future

    International Nuclear Information System (INIS)

    Sitek, J.; Necas, V.

    2012-01-01

    Concepts and international frames of generation IV nuclear reactors. A review of use of nuclear energy for non electric applications especially in areas such as seawater desalination, hydrogen production, district heating and other industrial applications. (Author)

  13. The - compromised? - future of natural gas; L'avenir - compromis? - du gaz naturel

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, Ph

    2009-05-15

    Will natural gas be the main loser of the January 2009 crisis between Ukraine and Russia? The demonstration is made that the European Union is not free from the risk of a severe supply disruption. This is a bad news considering that the power generation is the growth vector of natural gas. Even if the gas black-out cannot exist, the power black-out still can happen. As soon as the Russian-Ukrainian conflict has occurred, the other energy sources (nuclear and renewable) have been called for help in Europe while coal is in the expectation. Since some time now, gas has to face several trend changes. First, uncertainty is increasing considering its growth prospects. The new version of the gas pluri-annual indicative plan (PIP Gaz) would foresee a stagnation of gas consumption up to 2020 (consequence of the French environmental policy), while the previous plan had foreseen a 2.1% annual growth rate between 2005 and 2015. Second, the direct indexing of gas prices on oil prices can have undesirable effects. Finally, the u-turn of the USA with respect to liquefied natural gas (LNG) may penalize its development. What answers should the European Union give in front of these uncertainties? Have the companies modified their strategy? Is the future of gas still fine? These are the questions debated during a round table organized by the BIP, the French Bulletin of Petroleum Industry. (J.S.)

  14. Application and future of solid foams

    Science.gov (United States)

    Bienvenu, Yves

    2014-10-01

    To conclude this series of chapters on solid foam materials, a review of industrial current applications and of mid-term market perspectives centred on manmade foams is given, making reference to natural cellular materials. Although the polymeric foam industrial development overwhelms the rest and finds applications on many market segments, more attention will be paid to the emerging market of inorganic-especially metallic-foams (and cellular materials) and their applications, present or upcoming. It is shown that the final applications of solid foams are primarily linked to transport and the present-day development of the different classes of solid foams is contrasted between functional applications and structural applications. xml:lang="fr"

  15. Virtual Reality: Emerging Applications and Future Directions

    Science.gov (United States)

    Ludlow, Barbara L.

    2015-01-01

    Virtual reality is an emerging technology that has resulted in rapid expansion in the development of virtual immersive environments for use as educational simulations in schools, colleges and universities. This article presents an overview of virtual reality, describes a number of applications currently being used by special educators for…

  16. Future developments and applications of nitrogen-bearing steels ...

    Indian Academy of Sciences (India)

    M. Senthilkumar (Newgen Imaging) 1461 1996 Oct 15 13:05:22

    from the marketing of the new steel, as well as other new materials is vanishing dramatically. 4. Actual, future and possible applications. Industrial applications of existing austenitic, martensitic and duplex HNS have been described by Speidel in his book. HNS find applications in chemical industry, transportation, ship.

  17. Uprated OMS engine status and future applications

    Science.gov (United States)

    Boyd, W. C.; Brasher, W. L.

    1986-01-01

    The baseline Orbital Maneuvering Engine (OME) of the Space Shuttle has the potential for significant performance uprating, leading to increased Shuttle performance capability. The approach to uprating that is being pursued at the NASA Lyndon B. Johnson Space Center is the use of a gas generator-driven turbopump to increase OME operating pressure. A higher pressure engine can have a greater nozzle expansion ratio in the same envelope and at the same thrust level, giving increased engine Isp. The results of trade studies and analyses that have led to the preferred uprated OME configuration are described. The significant accomplishments of a pre-development component demonstration program are also presented, including descriptions of test hardware and discussion of test results. It is shown that testing to date confirms the capability of the preferred uprated OME configuration to meet or exceed performance and life requirements. Potential future activities leading up to a full-scale development program are described, and the capability for the uprated OME to be used in future storable propellant upper stages is discussed.

  18. Fuzzy technology present applications and future challenges

    CERN Document Server

    Fedrizzi, Mario; Kacprzyk, Janusz

    2016-01-01

    This book provides readers with a timely and comprehensive yet concise view on the field of fuzzy logic and its real-world applications. The chapters, written by authoritative scholars in the field, report on promising new models for data analysis, decision making, and systems modeling, with a special emphasis on their applications in management science. The book is a token of appreciation from the fuzzy research community to Professor Christer Carlsson for his long time research and organizational commitment, which have among other things resulted in the foundation and success of the Institute for Advanced Management Systems Research (IAMSR) at Åbo Akademi University, in Åbo (Turku), Finland. The book serves as timely guide for the fuzzy logic and operations research communities alike. .

  19. HTGR experience, programs, and future applications

    International Nuclear Information System (INIS)

    Moore, R.A.; Kantor, M.E.; Brey, H.L.; Olson, H.G.

    1982-01-01

    This paper reviews the current status of the programs for the development of high-temperature gas-cooled reactors (HTGRs) in the major industrial countries of the world. Existing demonstration plants and facilities are briefly described, and national programs for exploiting the unique high-temperature capabilities of the HTGR for commercial production of electricity and in process steam/heat application are discussed. (orig.)

  20. Artificial intelligence: contemporary applications and future compass.

    Science.gov (United States)

    Khanna, Sunali

    2010-08-01

    The clinical use of information technology in the dental profession has increased substantially in the past 10 to 20 years. In most developing countries an insufficiency of medical and dental specialists has increased the mortality of patients suffering from various diseases. Employing technology, especially artificial intelligence technology, in medical and dental application could reduce cost, time, human expertise and medical error. This approach has the potential to revolutionise the dental public health scenario in developing countries. Clinical decision support systems (CDSS) are computer programs that are designed to provide expert support for health professionals. The applications in dental sciences vary from dental emergencies to differential diagnosis of orofacial pain, radiographic interpretations, analysis of facial growth in orthodontia to prosthetic dentistry. However, despite the recognised need for CDSS, the implementation of these systems has been limited and slow. This can be attributed to lack of formal evaluation of the systems, challenges in developing standard representations, cost and practitioner scepticism about the value and feasibility of CDSS. Increasing public awareness of safety and quality has accelerated the adoption of generic knowledge based CDSS. Information technology applications for dental practice continue to develop rapidly and will hopefully contribute to reduce the morbidity and mortality of oral and maxillofacial diseases and in turn impact patient care.

  1. Wavelets and their applications past and future

    Science.gov (United States)

    Coifman, Ronald R.

    2009-04-01

    As this is a conference on mathematical tools for defense, I would like to dedicate this talk to the memory of Louis Auslander, who through his insights and visionary leadership, brought powerful new mathematics into DARPA, he has provided the main impetus to the development and insertion of wavelet based processing in defense. My goal here is to describe the evolution of a stream of ideas in Harmonic Analysis, ideas which in the past have been mostly applied for the analysis and extraction of information from physical data, and which now are increasingly applied to organize and extract information and knowledge from any set of digital documents, from text to music to questionnaires. This form of signal processing on digital data, is part of the future of wavelet analysis.

  2. L'effet tunnel dépendant du spin comme sonde du micromagnétisme et du transport d'électrons chauds : application aux capteurs

    OpenAIRE

    LACOUR, Daniel

    2002-01-01

    C. Chappert A. Fert M. Hehn F. Nguyen Van Dau A. Schuhl A. Thiaville; Studies of the spin dependent tunneling effect in ferromagnetic metal /insulating/ferromagnetic metal stacks are being actively pursued for their high application potential (magnetic sensors, random access memories, read heads... ). The resistance of these devices is directly link to the relative orientation of the electrode magnetizations. The high sensitivity of spin dependent tunneling effect to the electrodes magnetic c...

  3. Future applications of artificial intelligence to Mission Control Centers

    Science.gov (United States)

    Friedland, Peter

    1991-01-01

    Future applications of artificial intelligence to Mission Control Centers are presented in the form of the viewgraphs. The following subject areas are covered: basic objectives of the NASA-wide AI program; inhouse research program; constraint-based scheduling; learning and performance improvement for scheduling; GEMPLAN multi-agent planner; planning, scheduling, and control; Bayesian learning; efficient learning algorithms; ICARUS (an integrated architecture for learning); design knowledge acquisition and retention; computer-integrated documentation; and some speculation on future applications.

  4. Geomathematics theoretical foundations, applications and future developments

    CERN Document Server

    Agterberg, Frits

    2014-01-01

    This book provides a wealth of geomathematical case history studies performed by the author during his career at the Ministry of Natural Resources Canada, Geological Survey of Canada (NRCan-GSC). Several of the techniques newly developed by the author and colleagues that are described in this book have become widely adopted, not only for further research by geomathematical colleagues, but by government organizations and industry worldwide. These include Weights-of-Evidence modelling, mineral resource estimation technology, trend surface analysis, automatic stratigraphic correlation and nonlinear geochemical exploration methods. The author has developed maximum likelihood methodology and spline-fitting techniques for the construction of the international numerical geologic timescale. He has introduced the application of new theory of fractals and multifractals in the geostatistical evaluation of regional mineral resources and ore reserves and to study the spatial distribution of metals in rocks. The book also ...

  5. Superstructures: First Cold Test and Future Applications

    International Nuclear Information System (INIS)

    J. Sekutowicz; C Albrecht; V Ayvazyan; R Bandelmann; T Buttner; P Castro; S Choroba; J Eschke; B Faatz; A Gossel; K Honkavaara; B Horst; J Iverson; K Jensch; H Kaiser; R Kammering; G Kreps; D Kostin; J Lorkiewicz; R Lange; A Matheisen; W -D Moller; H -B Peters; D Proch; K Rehlich; H Schlarb; S Schrieber; D Reschke; S Simrock; W Singer; X Singer; K Twarowski; T Weichert; M Wojtkiewicz; G Wendt; K Zapfe; M Liepe; M Huening; M Ferrario; E Plawski; C Pagani; P Kneisel; G Wu; N Baboi; C Thomas; H Chen; W Huang; C Tang; S Zheng

    2003-01-01

    Superstructures, chains of superconducting multi-cell cavities (subunits) connected by e/2 long tube(s) have been proposed as an alternative layout for the TESLA main accelerator [1]. After three years of preparation, two superstructures, each made of two weakly coupled superconducting 7-cell subunits driven by a single Fundamental Power Coupler (FPC), have been installed in the Tesla Test Facility linac for beam tests. Energy stability, HOM damping, frequency and field adjustment methods were tested. The measured results confirme Superstructures, chains of superconducting multi-cell cavities (subunits) connected by e/2 long tube(s) have been proposed as an alternative layout for the TESLA main accelerator [1]. After three years of preparation, two superstructures, each made of two weakly coupled superconducting 7-cell subunits driven by a single Fundamental Power Coupler (FPC), have been installed in the Tesla Test Facility linac for beam tests. Energy stability, HOM damping, frequency and field adjustment methods were tested. The measured results confirmed expectation on the superstructure performance and proved that an alternative layout for the 800 GeV upgrade of the TESLA collider is feasible. We report on the test and give here an overview of its results. The tests confirmed very good damping of HOMs in superstructures and thus has opened a possible new application of this concept to high current energy recovery machines. We have built two 1.5 GHz copper models of two superstructures: 2x5-cells and 2x2-cells to prove further improvement of HOM damping. This contribution presents also measured results on these models. d expectations on the superstructure performance and proved that an alternative layout for the 800 GeV upgrade of the TESLA collider is feasible. We report on the test and give here an overview of its results

  6. Industrial Applications of the Surface-Enhanced Raman Spectroscopy Application industrielle du SERS

    Directory of Open Access Journals (Sweden)

    Nabiev I.

    2006-11-01

    Full Text Available Surface-enhanced Raman scattering (SERS spectroscopy is now a well-established phenomenon, which has been thoroughly characterized in a variety of interfacial and colloidal environments. Although some quantitative aspects of the underlying enhancement mechanisms apparently remain unresolved, attention is now shifting towards application of SERS to explore phenomena of chemical, physical, biological and industrial significance. The goal of this review is to appreciate the industrial value of innovative SERS technique on the basis of our experience in development of new SERS-active substrates and in their biomedical and biotechnological applications. Examples of diverse SERS analytical applications as well as some very recent facilities, as SERS microprobe analysis, SERS fiber optics probes, FT-SERS spectroscopy, SERS detection for high-performance liquid chromatography, etc. , are also discussed. Le SERS (Surface Enhanced Raman Spectroscopy est un phénomène aujourd'hui bien connu qui a été étudié dans toute une gamme de milieux interfaciaux et colloïdaux. Si certains aspects quantitatifs des mécanismes d'exaltation restent apparemment non résolus, l'attention se porte à présent vers l'application de la spectroscopie SERS à l'exploration de phénomènes présentant un intérêt chimique, physique, biologique et industriel. L'objectif de cet article est d'estimer la valeur industrielle des nouvelles techniques de spectroscopie SERS à partir de notre expérience dans le développement de nouveaux substrats actifs en SERS et leurs applications biomédicales et biotechnologiques. Les auteurs discutent également des exemples de diverses applications analytiques de la spectroscopie SERS ainsi que de quelques procédés très récents : analyse par microsonde SERS, sondes SERS à fibres optiques, spectroscopie FT-SERS, détection SERS pour la chromatographie haute performance en phase liquide, etc.

  7. The diverse applications of the nuclear power; Les diverses applications du nucleaire

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The three great categories of application in industry and environment of ionizing radiations are the use of ionizing radiation to transport energy in matter it is industrial irradiation, the use of radioactive sources of low activity to analyze and measure, it is the nucleonic instrumentation, the use of radioactive tracers to follow and study the matter transfer. Are explained the treatments to improve the plastic materials and the ionisation of food. (N.C.)

  8. RAPPORT DU SEMINAIRE DU 10 AVRIL 2013 A YAOUNDE

    Directory of Open Access Journals (Sweden)

    Bienvenu Denis Nizesete

    2015-02-01

    Full Text Available

    Rapport du séminaire du 10 Avril 2013 à Yaoundé

    Future and past historiography- gaps and silences in the archival record, and what we can say today about the future archival record

  9. Future of AI application to electric power field

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, Hideo; Sakaguchi, Toshiaki (The Tokyo Electric Power Co., Inc., Tokyo, Japan Mitsubishi Electric Corp., Tokyo (Japan))

    1989-08-20

    This report forecasts the future of applying ES (Expert System) to the power system based on the trend of an information treating technology and a social economy. The future power system will definitely find more advanced systems of the automatization and the business mechanization, and highly advanced communication and information system. Forecast tells that the 21st. Century will see the more highly informationalized system which may be called a computer-integrated power system. Then, the expert system will play an essential role. Up to this time, the front scene has been the application of ES to the power system, but the application of the robotics is also an important problem among the AI technologies. Application to the operation of monitoring, patrolling and operation is a problem of the future. Technical items to be researched and developed in the power system are a means of know-how expression and a large scale software system development. 8 refs., 1 fig.

  10. Nuclear systems of the future. Stakes, R and D strategy, and international cooperation; Les systemes nucleaires du futur. Enjeux, strategie de recherche et developpement, et cooperation internationale

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    As demonstrated by prospective studies, nuclear energy will represent a decisive contribution in the future energy mix. The long-term strategy of development of nuclear energy requires to foresee a new generation of nuclear systems, named generation 4. The goal of these new systems is to optimize the use of nuclear fuels, to minimize the generation of wastes and to enlarge the field of applications of nuclear energy to other applications like: hydrogen and synthetic fuels generation, heat generation for the industry etc. This document presents the French R and D strategy on nuclear systems of 4. generation that has been approved by the public authorities. This strategy follows three axes: a priority research on fast neutron systems with fuel recycle (sodium fast reactors (SFR) and gas fast reactors (GFR)), a research on key-technologies for the supply of very high temperature heat (very high temperature reactor (VHTR), fast and thermal neutron reactors, and water decomposition processes), and a continuation of researches on PWR reactors improvement. An integral recycling of all actinides in fast neutron reactors requires the development of new fuel reprocessing and fuel re-fabrication processes. A reference scenario for the progressive renewal of French nuclear facilities foresees the simultaneous development of fast neutron systems and the start-up of a new spent fuel reprocessing plant. France in involved in the development of the SFR, GFR and VHTR systems thanks to its participation to the Generation 4 international forum and to bilateral cooperation with other big nuclear partners like Russia and China. One of the main stakes of the French nuclear industry is to be able to invest in the R and D of future nuclear systems in order to valorize the experience gained so far in sodium FBR systems and in fuel cycle processes. (J.S.)

  11. Present and future applications of magnetic nanostructures grown by FEBID

    Science.gov (United States)

    De Teresa, J. M.; Fernández-Pacheco, A.

    2014-12-01

    Currently, magnetic nanostructures are routinely grown by focused electron beam induced deposition (FEBID). In the present article, we review the milestones produced in the topic in the past as well as the future applications of this technology. Regarding past milestones, we highlight the achievement of high-purity cobalt and iron deposits, the high lateral resolution obtained, the growth of 3D magnetic deposits, the exploration of magnetic alloys and the application of magnetic deposits for Hall sensing and in domain-wall conduit and magnetologic devices. With respect to future perspectives of the topic, we emphasize the potential role of magnetic nanostructures grown by FEBID for applications related to highly integrated 2D arrays, 3D nanowires devices, fabrication of advanced scanning-probe systems, basic studies of magnetic structures and their dynamics, small sensors (including biosensors) and new applications brought by magnetic alloys and even exchange biased systems.

  12. Present and future applications of magnetic nanostructures grown by FEBID

    Energy Technology Data Exchange (ETDEWEB)

    Teresa, J.M. de [CSIC-Universidad de Zaragoza, Departamento de Fisica de la Materia Condensada, Instituto de Ciencia de Materiales de Aragon (ICMA), Saragossa (Spain); Universidad de Zaragoza, Laboratorio de Microscopias Avanzadas (LMA), Instituto de Nanociencia de Aragon (INA), Saragossa (Spain); Fernandez-Pacheco, A. [University of Cambridge, TFM Group, Cavendish Laboratory, Cambridge (United Kingdom)

    2014-12-15

    Currently, magnetic nanostructures are routinely grown by focused electron beam induced deposition (FEBID). In the present article, we review the milestones produced in the topic in the past as well as the future applications of this technology. Regarding past milestones, we highlight the achievement of high-purity cobalt and iron deposits, the high lateral resolution obtained, the growth of 3D magnetic deposits, the exploration of magnetic alloys and the application of magnetic deposits for Hall sensing and in domain-wall conduit and magnetologic devices. With respect to future perspectives of the topic, we emphasize the potential role of magnetic nanostructures grown by FEBID for applications related to highly integrated 2D arrays, 3D nanowires devices, fabrication of advanced scanning-probe systems, basic studies of magnetic structures and their dynamics, small sensors (including biosensors) and new applications brought by magnetic alloys and even exchange biased systems. (orig.)

  13. Anticipating our future robot society : The evaluation of future robot applications from a user's perspective

    NARCIS (Netherlands)

    de Graaf, M.M.A.; Ben Allouch, Soumaya

    2016-01-01

    With an expected growth of robots in our future society, we believe that potential implications for robot applications should be addressed. Therefore, we conducted an online questionnaire among the general Dutch population (n= 1162) to map the societal impact of robots by identifying potential

  14. The electromagnetic spectrum: current and future applications in oncology.

    Science.gov (United States)

    Allison, Ron R

    2013-05-01

    The electromagnetic spectrum is composed of waves of various energies that interact with matter. When focused upon and directed at tumors, these energy sources can be employed as a means of lesion ablation. While the use of x-rays is widely known in this regard, a growing body of evidence shows that other members of this family can also achieve oncologic success. This article will review therapeutic application of the electromagnetic spectrum in current interventions and potential future applications.

  15. Plant retroviruses: structure, evolution and future applications | Zaki ...

    African Journals Online (AJOL)

    Until recently, retroviruses were thought to be restricted to vertebrates. Plant sequencing projects revealed that plant genomes contain retroviral-like sequences. This review aims to address the structure and evolution of plant retroviruses. In addition, it proposes future applications for these important key components of plant ...

  16. The FITTEST Tool Suite for Testing Future Internet Applications

    NARCIS (Netherlands)

    Vos, T.E.J.; Tonella, P.; Prasetya, I.S.W.B.; Kruse, P.M.; Shehory, O.; Bagnato, A.; Harman, M.

    2014-01-01

    Future Internet applications are expected to be much more complex and powerful, by exploiting various dynamic capabilities For testing, this is very challenging, as it means that the range of possible behavior to test is much larger, and moreover it may at the run time change quite frequently and

  17. DSP applications in advanced, intelligent motion control: the future

    Energy Technology Data Exchange (ETDEWEB)

    Beierke, S. [Texas Instruments Deutschland GmBh, Freising (Germany); Vas, P. [Univ. of Aberdeen, Dept. of Engineering (United Kingdom)

    2000-08-01

    Recently there has been a rapid increase in the number of DSPs for various motion control applications. However, in the future, further significant increase is expected due to wider applications in existing and new areas (e.g. household appliances, automotive auxiliaries, micro-electromechanical systems, military applications, etc.). The present paper discusses the state-of-art Texas Instruments fixed point and floating point DSPs used in motion control applications and will also focus on future activities. Currently new chip technologies are being developed which involve copper interconnects, silicon-on-insulator wafers, insulators with- low dielectric constants, etc. It is expected that future single-chip DSPs for advanced intelligent motion control will have higher performance, reduced costs, simpler designs, will incorporate various sensors, different modules for optimised PWM generation, efficiency control, vector and direct torque control (sensorless and quasisensorless solutions as well), condition monitoring, selfcommissioning, artificial-intelligence-based control, etc. A manufacturer's task of implementing sensorless and/or quasisensorless torque control schemes for induction, synchronous and switched reluctance motor drives will be significantly reduced by the application of the newly developed DSPs. The paper will discuss these issues and will also show some implementation results in various sensorless (classical DTC; DTC with torque-ripple reduction schemes; vector) and quasisensorless ac drives (e.g. a vector controlled induction motor drive). (orig.)

  18. Nanostructures: Current uses and future applications in food science.

    Science.gov (United States)

    Pathakoti, Kavitha; Manubolu, Manjunath; Hwang, Huey-Min

    2017-04-01

    Recent developments in nanoscience and nanotechnology intend novel and innovative applications in the food sector, which is rather recent compared with their use in biomedical and pharmaceutical applications. Nanostructured materials are having applications in various sectors of the food science comprising nanosensors, new packaging materials, and encapsulated food components. Nanostructured systems in food include polymeric nanoparticles, liposomes, nanoemulsions, and microemulsions. These materials enhance solubility, improve bioavailability, facilitate controlled release, and protect bioactive components during manufacture and storage. This review highlights the applications of nanostructured materials for their antimicrobial activity and possible mechanism of action against bacteria, including reactive oxygen species, membrane damage, and release of metal ions. In addition, an overview of nanostructured materials, and their current applications and future perspectives in food science are also presented. Copyright © 2017. Published by Elsevier B.V.

  19. Anatomie du nerf laryngé externe et ses applications chirurgicales ...

    African Journals Online (AJOL)

    Objectif : La lésion de la branche externe du nerf laryngé supérieur (BeNLS) , non rare lors de la chirurgie thyroïdienne, est responsable de modifications de la voix et de troubles de la déglutition. Mais ses différentes variantes anatomiques ainsi que les faibles taux de son identification ont découragé les chirurgiens de son ...

  20. 13 Facile application de la RMN du carbone-13 à l'identification et à ...

    African Journals Online (AJOL)

    AKA BOKO

    de bois [13] en utilisant l'analyse directe avec RMN du carbone-13 assistée par ordinateur sans séparation préalable ont démontré la facilité et fiabilité de cette méthode éminemment non invasive. Dans une étude antérieure, nous avons appliqué cette méthodologie dans l'analyse qualitative et quantitative des sucres.

  1. Application of adaptive antenna techniques to future commercial satellite communication

    Science.gov (United States)

    Ersoy, L.; Lee, E. A.; Matthews, E. W.

    1987-01-01

    The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further sub-divided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

  2. Transcranial brain stimulation: clinical applications and future directions.

    Science.gov (United States)

    Najib, Umer; Bashir, Shahid; Edwards, Dylan; Rotenberg, Alexander; Pascual-Leone, Alvaro

    2011-04-01

    Noninvasive brain stimulation is a valuable investigative tool and has potential therapeutic applications in cognitive neuroscience, neurophysiology, psychiatry, and neurology. Transcranial magnetic stimulation (TMS) is particularly useful to establish and map causal brain-behavior relations in motor and nonmotor cortical areas. Neuronavigated TMS is able to provide precise information related to the individual's functional anatomy that can be visualized and used during surgical interventions and critically aid in presurgical planning, reducing the need for riskier and more cumbersome intraoperative or invasive mapping procedures. This article reviews methodological aspects, clinical applications, and future directions of TMS-based mapping. Copyright © 2011 Elsevier Inc. All rights reserved.

  3. Nuclear systems of the future: international forum generation 4 and research and development projects at the Cea; Systemes nucleaires du futur: forum international generation 4 et projets de R et D du CEA

    Energy Technology Data Exchange (ETDEWEB)

    Carre, F

    2003-07-01

    To advance nuclear energy to meet future energy needs, ten countries have agreed to develop a future generation of nuclear energy systems, known as Generation 4. A technology road map to guide the Generation 4 effort was begun. This document presents the goals for these nuclear systems and the research programs of the Cea on the gas technology, GT-MHR, VHTR and GFR and the other systems as sodium Fast Neutron reactors, supercritical water and space nuclear. (A.L.B.)

  4. Radiation hard diamond sensors for future tracking applications

    International Nuclear Information System (INIS)

    Adam, W.; Boer, W. de; Borchi, E.

    2006-01-01

    Progress in experimental particle physics in the coming decade depends crucially upon the ability to carry out experiments in high-radiation areas. In order to perform these complex and expensive experiments, new radiation hard technologies must be developed. This paper discusses the use of diamond detectors in future tracking applications and their survivability in the highest radiation environments. We present results of devices constructed with the newest polycrystalline and single crystal Chemical Vapor Deposition diamond and their tolerance to radiation

  5. Technique du Micro-Enseignement: Une Approche Pour Enseigner La Pratique de La Lecture aux Apprenants de Niveau A2 et La Perception de Cette Technique Par Les Futurs Enseignants

    Directory of Open Access Journals (Sweden)

    Nurten ÖZÇELİK

    2017-09-01

    Full Text Available Cette étude a été préparée en vue de déterminer les difficultés rencontrées par les futurs enseignants lors de l’enseignement de la lecture aux apprenants de niveau A2 par la technique du micro-enseignement, et de mettre à jour leurs opinions concernant les avantages ainsi que les inconvénients de cette technique. Le groupe de travail est composé de 20 futurs enseignants (14 femmes, 6 hommes du Département de la Didactique du FLE de la Faculté Pédagogique de l’Université Gazi, pour le deuxième semestre de la période 2014-2015. Les données recueillies par les questions à réponses ouvertes ont été évaluées par la méthode de l’analyse descriptive, à la suite des calculs de fréquence. Selon les résultats obtenus, les futurs enseignants ont surtout du mal à prononcer le français, à gérer leurs émotions, à préparer une présentation, des activités de pré-lecture et du dossier de présentation. Augmenter la confiance en soi, apprendre à préparer un plan de cours, donner la possibilité de voir les aspects insuffisants sont les points positifs de la technique. L’insuffisance des participations au cours, l’artificialité du milieu de la classe, la subjectivité des critiques des pairs sont indiqués par les participants comme les inconvénients de cette technique.

  6. Application du concept de maillon faible à un critère d'endurance multiaxial

    Science.gov (United States)

    Flacelière, L.; Morel, F.; Palin-Luc, T.

    2002-12-01

    En fatigue à grand nombre de cycle, il est aujourd'hui admis que la distribution des contraintes, ainsi que la taille des composants, sont responsables de variations de la limite de fatigue. Sous chargement uniaxial ou multiaxial, on peut montrer qu'une approche statistique dite du maillon le plus faible, combiné à un critère multiaxial d'endurance basé sur une analyse micro plastique, permet de prédire la limite de fatigue de plusieurs matériaux métalliques. Quatre types de chargement sont analysés (traction-compression, torsion, flexion rotative et flexion plane), puis comparées aux résultats expérimentaux, pour une fonte et deux aciers haute résistance. L'approche statistique proposée permet d'intégrer un certain nombre d'aspects: la dispersion des données pour tous types de chargement, l'effet de gradient et l'influence de la présence de défauts matériaux. Enfin, ce modèle rend également compte de la diminution de la limite de fatigue avec l'augmentation du volume contraint. Les prédictions des probabilités de rupture sont raisonnables bien que seules des limites de fatigue relatives à des probabilités de rupture de 50% soient utilisées pour l'identification des paramètres du modèle.

  7. Nanotechnology: current uses and future applications in the food industry.

    Science.gov (United States)

    Thiruvengadam, Muthu; Rajakumar, Govindasamy; Chung, Ill-Min

    2018-01-01

    Recent advances in nanoscience and nanotechnology intend new and innovative applications in the food industry. Nanotechnology exposed to be an efficient method in many fields, particularly the food industry and the area of functional foods. Though as is the circumstance with the growth of any novel food processing technology, food packaging material, or food ingredient, additional studies are needed to demonstrate the potential benefits of nanotechnologies and engineered nanomaterials designed for use in foods without adverse health effects. Nanoemulsions display numerous advantages over conventional emulsions due to the small droplets size they contain: high optical clarity, excellent physical constancy against gravitational partition and droplet accumulation, and improved bioavailability of encapsulated materials, which make them suitable for food applications. Nano-encapsulation is the most significant favorable technologies having the possibility to ensnare bioactive chemicals. This review highlights the applications of current nanotechnology research in food technology and agriculture, including nanoemulsion, nanocomposites, nanosensors, nano-encapsulation, food packaging, and propose future developments in the developing field of agrifood nanotechnology. Also, an overview of nanostructured materials, and their current applications and future perspectives in food science are also presented.

  8. A Decomposition of Hospital Profitability: An Application of DuPont Analysis to the US Market.

    Science.gov (United States)

    Turner, Jason; Broom, Kevin; Elliott, Michael; Lee, Jen-Fu

    2015-01-01

    This paper evaluates the drivers of profitability for a large sample of U.S. hospitals. Following a methodology frequently used by financial analysts, we use a DuPont analysis as a framework to evaluate the quality of earnings. By decomposing returns on equity (ROE) into profit margin, total asset turnover, and capital structure, the DuPont analysis reveals what drives overall profitability. Profit margin, the efficiency with which services are rendered (total asset turnover), and capital structure is calculated for 3,255 U.S. hospitals between 2007 and 2012 using data from the Centers for Medicare & Medicaid Services' Healthcare Cost Report Information System (CMS Form 2552). The sample is then stratified by ownership, size, system affiliation, teaching status, critical access designation, and urban or non-urban location. Those hospital characteristics and interaction terms are then regressed (OLS) against the ROE and the respective DuPont components. Sensitivity to regression methodology is also investigated using a seemingly unrelated regression. When the sample is stratified by hospital characteristics, the results indicate investor-owned hospitals have higher profit margins, higher efficiency, and are substantially more leveraged. Hospitals in systems are found to have higher ROE, margins, and efficiency but are associated with less leverage. In addition, a number of important and significant interactions between teaching status, ownership, location, critical access designation, and inclusion in a system are documented. Many of the significant relationships, most notably not-for-profit ownership, lose significance or are predominately associated with one interaction effect when interaction terms are introduced as explanatory variables. Results are not sensitive to the alternative methodology. The results of the DuPont analysis suggest that although there appears to be convergence in the behavior of NFP and IO hospitals, significant financial differences remain

  9. Nanotechnology-enhanced orthopedic materials fabrications, applications and future trends

    CERN Document Server

    Yang, Lei

    2015-01-01

    Nanotechnology-Enhanced Orthopedic Materials provides the latest information on the emergence and rapid development of nanotechnology and the ways it has impacted almost every aspect of biomedical engineering. This book provides readers with a comprehensive overview of the field, focusing on the fabrication and applications of these materials, presenting updated, practical, and systematic knowledge on the synthesis, processing, and modification of nanomaterials, along with the rationale and methodology of applying such materials for orthopedic purposes. Topics covered include a wide range of orthopedic material formulations, such as ceramics, metals, polymers, biomolecules, and self-assemblies. Final sections explore applications and future trends in nanotechnology-enhanced orthopedic materials. Details practical information on the fabrication and modification of new and traditional orthopedic materials Analyzes a wide range of materials, designs, and applications of nanotechnology for orthopedics Investigate...

  10. Application of Mathematical Signal Processing Techniques to Mission Systems. (l’Application des techniques mathematiques du traitement du signal aux systemes de conduite des missions)

    Science.gov (United States)

    1999-11-01

    Acad. Sei. Paris A, 319, (1994), pp. 1317-1322. 6-12 [8] Joel H. Ferziger, Numerical Methods for Engi- neering Application, Wiley and Sons, New...pp. 202-207, June 1991. [37] A. Witkin , "Scale-space filtering," International Joint Conference on Artificial Intelligence, Karl- sruhe, pp. 1019

  11. Voyage au cœur d’un futur inconnu : analyse du genre dans le cinéma de science-fiction chinois du nouveau millénaire

    OpenAIRE

    Yang, Wei

    2017-01-01

    Cet article étudie le cinéma de science-fiction comme nouveau genre du cinéma chinois. Tout en empruntant largement à son équivalent hollywoodien – costumes, décor, intrigue, caractérisation, effets visuels, et ainsi de suite – le cinéma de science-fiction chinois met rarement en scène les conceptions ou explorations scientifiques qui ont marqué un grand nombre de films de science-fiction ambitieux en Occident. En partie à cause du monopole hollywoodien du genre, les films de science-fiction ...

  12. Nanomaterials in Food - Current and Future Applications and Regulatory Aspects

    International Nuclear Information System (INIS)

    Aschberger, K; Gottardo, S; Amenta, V; Arena, M; Moniz, F Botelho; Mech, A; Pesudo, L Quiros; Rauscher, H; Bouwmeester, H; Brandhoff, P; Peters, R; Schoonjans, R; Vettori, M Vittoria

    2015-01-01

    Nanotechnology can contribute to the development of innovative applications in the agriculture, food and feed sector by e.g. enabling improved delivery of nutrients or increased efficacy of agrichemicals. It is expected that applications will increase in the near future and may therefore become a relevant source of human exposure to nanomaterials (NM). To gain more up-to date information, RIKILT and the Joint Research Centre (JRC) were commissioned by the European Food Safety Authority (EFSA) to prepare an inventory of currently used and reasonably foreseen applications of NM in agriculture and food/feed production and carried out a review of regulatory aspects concerning NM in both EU and non-EU countries. An analysis of the information records in the inventory shows that nano-encapsulates, silver and titanium dioxide are the most frequent type of NM listed and that food additives and food contact materials are the most frequent types of application. A comparison between marketed applications and those in development indicates a trend from inorganic materials (e.g. silver) towards organic materials (nano-encapsulates, nanocomposites). Applications in novel food, feed additives, biocides and pesticides are currently mostly at a developmental stage. The review of EU and non-EU legislation shows that currently a few EU legal acts incorporate a definition of a nanomaterial and specific provisions for NM, whereas in many non-EU countries a broader approach is applied, which mainly builds on guidance for industry. (paper)

  13. Nanomaterials in Food - Current and Future Applications and Regulatory Aspects

    Science.gov (United States)

    Aschberger, K.; Gottardo, S.; Amenta, V.; Arena, M.; Botelho Moniz, F.; Bouwmeester, H.; Brandhoff, P.; Mech, A.; Quiros Pesudo, L.; Rauscher, H.; Schoonjans, R.; Vittoria Vettori, M.; Peters, R.

    2015-05-01

    Nanotechnology can contribute to the development of innovative applications in the agriculture, food and feed sector by e.g. enabling improved delivery of nutrients or increased efficacy of agrichemicals. It is expected that applications will increase in the near future and may therefore become a relevant source of human exposure to nanomaterials (NM). To gain more up-to date information, RIKILT and the Joint Research Centre (JRC) were commissioned by the European Food Safety Authority (EFSA) to prepare an inventory of currently used and reasonably foreseen applications of NM in agriculture and food/feed production and carried out a review of regulatory aspects concerning NM in both EU and non-EU countries. An analysis of the information records in the inventory shows that nano-encapsulates, silver and titanium dioxide are the most frequent type of NM listed and that food additives and food contact materials are the most frequent types of application. A comparison between marketed applications and those in development indicates a trend from inorganic materials (e.g. silver) towards organic materials (nano-encapsulates, nanocomposites). Applications in novel food, feed additives, biocides and pesticides are currently mostly at a developmental stage. The review of EU and non-EU legislation shows that currently a few EU legal acts incorporate a definition of a nanomaterial and specific provisions for NM, whereas in many non-EU countries a broader approach is applied, which mainly builds on guidance for industry.

  14. Schumpeter, Marx et Walras. Entrepreneur et devenir du capitalisme Schumpeter, Marx and Walras. The entrepreneur and the future of capitalism

    Directory of Open Access Journals (Sweden)

    Sophie Boutillier

    2012-11-01

    Full Text Available Schumpeter invente l’entrepreneur pour conceptualiser l’acte d’innovation dont le modèle de l’économie pure de Walras est incapable de rendre compte. Ce faisant, il se rapproche de Marx. Dans cet article, nous proposons de revenir sur les deux économistes nodaux, Walras et Marx, qui ont en quelque sorte balisé l’œuvre de Schumpeter. Admiratif de l’œuvre de l’un et de l’autre, celui-ci a entrepris à les dépasser. Est-il vraiment parvenu à le faire? L’entrepreneur, d’une part, dans l’œuvre de Schumpeter reste une entité abstraite, alors qu’il avait pour ambition de pallier à l’abstraction walrasienne. De l’autre côté, il ne peut que constater la bureaucratisation, via la concentration, de la production capitaliste qui devient la norme du capitalisme managérial.Schumpeter invented the entrepreneur to conceptualize the innovation act that the model of pure economy of Walras was unable to explain. In doing so, he converged to Marx. In this paper, we propose to come back to the two nodal economists, Walras and Marx, who marked the work of Schumpeter. Admiring the work of the one and of the other, Schumpeter aimed to go further. Did he really succeed to do so? On the one hand, in Schumpeter’s work, the entrepreneur remains an abstract entity, although he had the ambition to find a solution to the Walrasian abstraction. On the other hand, he could only observe the bureaucracy - through the concentration process - of the capitalist production which had become the norm of managerial capitalism.

  15. Le futur prix de l'énergie : faut-il orienter les prix du pétrole vers la hausse? The Future Price of Energy. Should Oil Prices Be Allowed to Driff Upwards?

    Directory of Open Access Journals (Sweden)

    Desprairies P.

    2006-11-01

    Full Text Available II est à peu près universellement admis que les prix du pétrole vont augmenter d'ici la fin du siècle, du fait de l'épuisement des ressources de pétrole conventionnel à bon marché. L'évolution souhaitable des prix et leur niveau futur font par contre l'objet d'opinions variées. L'analyse du problème ne fait pas apparaître de raisons d'une hausse immédiate des prix au pétrole brut, ni de leur alignement à échéance rapide sur le prix des pétroles non-conventionnels les plus chers. Dans les prochaines années c'est l'offre et la demande de pétrole conventionnel qui commanderont les prix du pétrole, c'est-à-dire, le rythme d'investissements dans le pétrole conventionnel, le charbon, et l'électricité nucléaire. La hausse en prix constants peut difficilement reprendre avant qu'aient disparu les surplus de capacité de production, c'est-à-dire guère avant 1983/1985 si la croissance économique et l'offre de pétrole continuent d'évoluer aux allures actuellement prévisibles. Si l'on est tenté d'évaluer aux alentours du prix de vente actuel majoré de 50 %, soit une vingtaine de dollars (1978 le prix à long terme du pétrole, c'est beaucoup plus par référence aux souhaits supposés des pays producteurs et au pouvoir d'achat des pays acheteurs qu'au coct de production du pétrole non-conventionnel. Il est aujourd'hui peu probable que le dialogue entre pays exportateurs et acheteurs de pétrole, point de départ d'une hausse programmée des prix, se noue avant qu'une crise d'approvisionnements plus ou moins sévère n'ait rendu manifeste la nécessité d'un tel dialogue. It is almost universolly accepted that oil prices will rise between now and the end of the century on account of the depletion of cheop conventional oil resources. The evolution to be desired for prices and their future level, on the other hand, is the subiect of differing opinions. An onalysis of the problem does not reveal any raasons for an immediate

  16. Atlas tomodensitométrique avec injection de produit de contraste du grasset du chien : application à la rupture du ligament croisé crânial et comparaison aux autres techniques d'imagerie

    OpenAIRE

    Tran-Dac, Émilie

    2010-01-01

    L’objectif de cette étude est de réaliser un atlas de référence des coupes tomodensitométriques du grasset du chien sain, avec injection de produit de contraste, et d’étudier son intérêt dans des cas de rupture du ligament croisé crânial. Cette affection est souvent associée à des lésions méniscales, dont la détection est difficile. La radiographie ne montre que des images indirectes de dégénérescence articulaire. L’échographie et l’IRM permettent une exploration sensible et spécifique, mais ...

  17. Application du groupe de renormalisation aux conducteurs organiques quasi-unidimensionnels soumis a un champ magnetique

    Science.gov (United States)

    Hubert, Laurent

    Des conducteurs organiques fortement anisotropes presentent, sous l'effet d'un champ magnetique, une etonnante variete de proprietes physiques tel que: l'effet Shubnikov-de Haas, l'effet de Haas-van-Alphen, l'existence de cascades d'ondes de densite de spin apparentees a l'effet Hall quantique, reentrance vers la phase metallique pouvant provenir d'un 'breakdown' magnetique, et tout recemment la possibilite d'un confinement charge induit par le champ magnetique. A cela s'ajoute les nombreuses caracteristiques deja apparues en variant la pression hydrostatique ou la substitution chimique: separation spin-charge, localisation de la charge, transition spin-Peierls, antiferromagnetisme itinerant ou non, supraconductivite, et l'existence d'une frontiere commune entre les phases supraconductrice et antiferromagnetique. En vue de completer la description theorique du diagramme de phase generalise des conducteurs organiques, nous adaptons et elargissons la methode du groupe de renormalisation quantique (GRQ) au cas ou le champ magnetique est non nul. On sait deja que cette methode permet de resoudre le dilemme tout particulier des composes Q-1D, soit leur capacite de produire des transitions de phase malgre leur forte anisotropie et consequemment de leur faible dimensionalite. Cette methode est deja utilisee pour decrire le diagramme de phase temperature versus pression des sels de Bechgaard, de leurs analogues souffres et mixtes. Le GRQ permet aussi de comprendre comment des systemes anisotropes comme les conducteurs organiques peuvent se comporter comme des liquides de Luttinger a haute temperature et comme des liquides de Fermi ou condenses a basse temperature. Nous montrons que l'introduction d'un champ magnetique dans un regime de saut coherent interchai ne a deux particules n'apporte que de simples corrections aux lois d'echelles dans le canal zero son, alors qu'il introduit un mecanisme de brisure de paire dans le canal Cooper. Dans le regime de saut coherent a une

  18. Past and future fracturing in AECL Research areas in the superior province of the Canadian Precambrian Shield, with emphasis on the Lac du Bonnet Batholith

    International Nuclear Information System (INIS)

    Brown, A.; Everitt, R.A.; Martin, C.D.; Davison, C.C.

    1995-10-01

    The likelihood that future fracturing, arising from geologic causes, could occur in the vicinity of a nuclear fuel waste repository in plutonic rock of the Canadian Precambrian Shield, is examined. The report discusses the possible causes of fracturing (both past and future) in Shield rocks. The report then examines case histories of fracture formation in Precambrian plutonic rocks in AECL's Research Areas, especially the history of the Lac du Bonnet Batholith, in the Whiteshell Area, Manitoba. Initially, fractures can be introduced into intrusive plutonic rocks during crystallization and cooling of an intrusive magma. These fractures are found at all size scales; as late residual magma dyking, hydraulic fracturing by retrograde boiling off of hydrothermal fluids, and, in some cases, through local differential cooling. Subsequent fracturing is largely caused by changes in environmental temperature and stress field, rather than by alteration of the material behaviour of the rock. Pluton emplacement during orogeny is commonly accompanied by uplift and erosional exhumation, altering both the tectonic and the lithostatic stresses, the rock temperature gradient and the pore fluid characteristics

  19. Real cases study through computer applications for futures Agricultural Engineers

    Science.gov (United States)

    Moratiel, R.; Durán, J. M.; Tarquis, A. M.

    2010-05-01

    One of the huge concerns on the higher engineer education is the lag of real cases study that the future professionals need in the work and corporation market. This concern was reflected in Bologna higher education system including recommendations in this respect. The knowhow as why this or other methodology is one of the keys to resolve this problem. In the last courses given in Department of Crop Production, at the Agronomy Engineer School of Madrid (Escuela Técnica Superior de Ingenieros Agrónomos, UPM) we have developed more than one hundred applications in Microsoft Excel®. Our aim was to show different real scenarios which the future Agronomic Engineers can be found in their professional life and with items related to crop production field. In order to achieve our target, each application in Excel presents a file text in which is explained the theoretical concepts and the objectives, as well as some resources used from Excel syntax. In this way, the student can understand and use of such application, even they can modify and customize it for a real case presented in their context and/or master project. This electronic monograph gives an answer to the need to manage data in several real scenarios showed in lectures, calculus resolution, information analysis and manage worksheets in a professional and student level.

  20. Plantes tinctoriales des traditions et sociétés du Pacifique : de la sauvegarde des savoirs aux nouvelles perspectives d'application

    OpenAIRE

    Cardon, D.; Cabalion, Pierre; Blanc, B.; Boulanger-Penduff, M.; Hnawia, E.; Nowik, W.; Waikedre, Jean; Sam, C.

    2010-01-01

    Les colorants naturels, utilisés depuis les temps préhistoriques, sont principalement extraits du monde végétal. Les applications des plantes tinctoriales ont concerné non seulement textiles et vannerie, mais aussi la peinture ou teinture de la peau et des cuirs, des cheveux et poils, etc. Des exemples de leur importance dans le patrimoine culturel des sociétés du Pacifique sont présentés, en développant celui de recherches interdisciplinaires récentes, d'ordre botanique, chimique et anthropo...

  1. Radiant coolers - Theory, flight histories, design comparisons and future applications

    Science.gov (United States)

    Donohoe, M. J.; Sherman, A.; Hickman, D. E.

    1975-01-01

    Radiant coolers have been developed for application to the cooling of infrared detectors aboard NASA earth observation systems and as part of the Defense Meteorological Satellite Program. The prime design constraints for these coolers are the location of the cooler aboard the satellite and the satellite orbit. Flight data from several coolers indicates that, in general, design temperatures are achieved. However, potential problems relative to the contamination of cold surfaces are also revealed by the data. A comparison among the various cooler designs and flight performances indicates design improvements that can minimize the contamination problem in the future.

  2. Stir bar sorptive extraction: recent applications, limitations and future trends.

    Science.gov (United States)

    Camino-Sánchez, F J; Rodríguez-Gómez, R; Zafra-Gómez, A; Santos-Fandila, A; Vílchez, J L

    2014-12-01

    Stir bar sorptive extraction (SBSE) has generated growing interest due to its high effectiveness for the extraction of non-polar and medium-polarity compounds from liquid samples or liquid extracts. In particular, in recent years, a large amount of new analytical applications of SBSE has been proposed for the extraction of natural compounds, pollutants and other organic compounds in foods, biological samples, environmental matrices and pharmaceutical products. The present review summarizes and discusses the theory behind SBSE and the most recent developments concerning its effectiveness. In addition, the main results of recent analytical approaches and their applications, published in the last three years, are described. The advantages, limitations and disadvantages of SBSE are described and an overview of future trends and novel extraction sorbents and supports is given. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. Biopesticide Formulations, Possibility of Application and Future Trends

    Directory of Open Access Journals (Sweden)

    Slavica Gašić

    2013-01-01

    Full Text Available Biopesticides are the formulated form of active ingredients based on microorganismssuch as bacteria, viruses, fungi, nematodes or naturally-occurring substances, includingplant extracts and semiochemicals (e.g. insect pheromones. Application of biopesticides isstill limited to only a few percent of all pesticides used for crop protection. There are manyfactors contributing to that situation, such as expensive production methods, poor storagestability, susceptibility to environmental conditions, efficacy problems, etc. Some ofthese problems can be overcome by formulation improvements. With many pressures onproduct performance formulation is becoming the most important area to enhance andextend the activity of biopesticides. In this paper we reviewed different types of biopesticidesexisting on the market and discussed possibilities for their application and current status.The expected future trends in formulation development of biopesticides are explained

  4. Polythiophene nanocomposites for photodegradation applications: Past, present and future

    Directory of Open Access Journals (Sweden)

    Mohd Omaish Ansari

    2015-09-01

    Full Text Available Polythiophene (PTh has been the subject of considerable interest because of its good environmental stability, unique redox electrical behavior, stability in doped or neutral states, ease of synthesis, and wide range of applications in many fields. Apart from its applications in the electrical or electronic field, PTh has shown promising applications in photocatalytic degradation. The fabrication of a catalyst, metal oxides with PTh, extends the absorption range of the modified composite system, thereby enhancing the photocatalytic activity under UV or visible light irradiation. Substituted PTh, such as alkyl substitution, modifies the electronic properties of the polymer, thereby enlarging the potential for industrial applications. PTh or substituted PTh when combined with metal, metal oxide or a combination of both, can exhibit tailorable photocatalytic properties. This review focuses on the chemistry of the band gap engineering of PTh or PTh based systems and the mechanism of photocatalytic degradation. The major developments in the field of UV and visible light-assisted photocatalysis are discussed in terms of the parameters that affect the photocatalytic efficiency. On the other hand, some challenges still needs to be investigated experimentally, which are mentioned as the scope for future studies. For simplicity, the review has been classified under a major subheading depending on the type of composite system used for photocatalysis.

  5. The changing world of gas exploration present and future trends; Les evolutions dans le secteur de l'exploration du gaz tendances actuelles et futures

    Energy Technology Data Exchange (ETDEWEB)

    Duval, B.C. [Institut Francais du Petrole (IFP), 92 - Rueil-Malmaison (France); Maisonnier, G. [Gedigaz, France (France)

    2000-07-01

    The industry has, in the past decade, added much more gas than it has produced, resulting in a 36% increase in world reserves. Therefore the resource base is no longer considered a serious constraint in satisfying the industry's needs. Under such circumstances, one may ask the question: is exploration for gas still needed? One way in which we may deal with this major issue would be to analyse the changes that occur in the upstream world, in relation to technology, the general business context and industry's strategies and their potential impact on future trends. Dramatic advancements in exploration technologies have helped to improve success ratios and prediction of fluid, and to open new prospective areas, while also reducing costs. From a State point of view, exploration constitutes a long term objective to contend with natural gas consumption growth without depending too much on imports, or to develop resources for exports. From a company perception, exploration appears as a necessity not only for future growth but also for geographical or geopolitical opportunities. Gas reserve additions will come increasingly from a combination of exploration and production deals. The numerous new opportunities created by a more open business environment will facilitate such developments. (authors)

  6. The nuclear energy of the future: the researches and the objectives; L'energie nucleaire du futur: quelles recherches pour quels objectifs?

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    Today energy problems are global problems. That is why the new generation of energy production by nuclear power must be realized basely on serious forecasts at a world scale. The nuclear energy presents many trumps for an energetic answer, at long-dated, concerning the environment and the resources. This will be for two main conditions: the ability to answer the public opinion anxiety and the development of new systems more high- performance in terms of safety and economy in the framework of the sustainable development and the non proliferation policy. These subjects are at the earth of the CEA missions. This document proposes a detailed presentation of the nuclear origins, the fuel and its cycle, the radioactive wastes and their management,the dismantling and the decommissioning of the nuclear installations, the challenges of the nuclear safety, the energy in the world, the nuclear economy, the nuclear in the world, the researches of the future, the third generation reactors, the research on radioactive wastes, the fuel cycle of the nuclear systems of the future, the uranium resources, the generation four forum, the gas coolant reactors, the thorium, hybrid systems and the thermonuclear fusion. (A.L.B.)

  7. Wireless Technology Use Case Requirement Analysis for Future Space Applications

    Science.gov (United States)

    Abedi, Ali; Wilkerson, DeLisa

    2016-01-01

    This report presents various use case scenarios for wireless technology -including radio frequency (RF), optical, and acoustic- and studies requirements and boundary conditions in each scenario. The results of this study can be used to prioritize technology evaluation and development and in the long run help in development of a roadmap for future use of wireless technology. The presented scenarios cover the following application areas: (i) Space Vehicles (manned/unmanned), (ii) Satellites and Payloads, (iii) Surface Explorations, (iv) Ground Systems, and (v) Habitats. The requirement analysis covers two parallel set of conditions. The first set includes the environmental conditions such as temperature, radiation, noise/interference, wireless channel characteristics and accessibility. The second set of requirements are dictated by the application and may include parameters such as latency, throughput (effective data rate), error tolerance, and reliability. This report provides a comprehensive overview of all requirements from both perspectives and details their effects on wireless system reliability and network design. Application area examples are based on 2015 NASA Technology roadmap with specific focus on technology areas: TA 2.4, 3.3, 5.2, 5.5, 6.4, 7.4, and 10.4 sections that might benefit from wireless technology.

  8. Continuous cultivation of photosynthetic microorganisms: Approaches, applications and future trends.

    Science.gov (United States)

    Fernandes, Bruno D; Mota, Andre; Teixeira, Jose A; Vicente, Antonio A

    2015-11-01

    The possibility of using photosynthetic microorganisms, such as cyanobacteria and microalgae, for converting light and carbon dioxide into valuable biochemical products has raised the need for new cost-efficient processes ensuring a constant product quality. Food, feed, biofuels, cosmetics and pharmaceutics are among the sectors that can profit from the application of photosynthetic microorganisms. Biomass growth in a photobioreactor is a complex process influenced by multiple parameters, such as photosynthetic light capture and attenuation, nutrient uptake, photobioreactor hydrodynamics and gas-liquid mass transfer. In order to optimize productivity while keeping a standard product quality, a permanent control of the main cultivation parameters is necessary, where the continuous cultivation has shown to be the best option. However it is of utmost importance to recognize the singularity of continuous cultivation of cyanobacteria and microalgae due to their dependence on light availability and intensity. In this sense, this review provides comprehensive information on recent breakthroughs and possible future trends regarding technological and process improvements in continuous cultivation systems of microalgae and cyanobacteria, that will directly affect cost-effectiveness and product quality standardization. An overview of the various applications, techniques and equipment (with special emphasis on photobioreactors) in continuous cultivation of microalgae and cyanobacteria are presented. Additionally, mathematical modeling, feasibility, economics as well as the applicability of continuous cultivation into large-scale operation, are discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

  9. Study on the application of 3D modeling based on UAV photography in urban planning — Taking Yi Jiequ area in Du Jiangyan as an example

    Science.gov (United States)

    Zhang, Bingshuang; Zhang, Lingqing

    2017-08-01

    This paper proposed a new technique combining UAV (unmanned aerial vehicle) with 3D (three-dimension) modeling to integrate and analyze a large amount of information and to guide urban planning. This paper expounded the status and methods of UAV applying to 3D modeling, verified the practical values of this technique and summarized the future development trend by taking Yi Jiequ area in Du Jiangyan as an example.

  10. Future trends in the application of isotopes and radiation

    International Nuclear Information System (INIS)

    Glubrecht, H.

    1977-01-01

    medicine and biomedical research is radioimmunoassay (RIA). Measurement of elemental composition of human body samples also has a high diagnostic value for large-scale screening of infectious and non-infectious diseases. Strong increase is to be foreseen in the application of gauges and other radiation analytical methods. Promising techniques in the petrol industry are the quantitative determination of hydrocarbon saturation by the use of pulsed-neutron capture logs and logs based on measurements of gamma rays from inelastic neutron scattering. Mineral exploration and mining may strongly profit from the development of portable EDXRF instruments using isotopic sources and high resolution Si(Li) detectors. In basic studies of process dynamics, tracer techniques may play an increasing role, particularly in the optimization of low-grade ore exploitation. Ionizing radiation can produce cross-linking and grafting in plastic and rubber. It is to be expected that more attention will be paid to these energy-saving processes in the future. The use of ?natural? isotope measurements ( 14 C, 3 H) and of isotope ratios ( 2 H/ 1 H, 18 O/ 16 O) has probably reached the highest level of sophistication in its application to problems associated with the assessment of water resources. The world-wide energy problem has prompted a new assessment of the potential of geothermal sources of energy. Environmental isotopes are being used in the hydrological study of geothermal systems environmental control and monitoring without making use of nuclear methods. NAA and EDXRF allow fast screening of more than 30 elements of importance in environmental pollution control. Future trends can be described by extrapolating from the present situation. Although the trends discussed in this paper may change it is clear that isotopes and radiation have an increasingly wide field of application i and strong future developments

  11. Modelling of gecko foot for future robot application

    Science.gov (United States)

    Kamaruddin, A.; Ong, N. R.; Aziz, M. H. A.; Alcain, J. B.; Haimi, W. M. W. N.; Sauli, Z.

    2017-09-01

    Every gecko has an approximately million microscale hairs called setae which made it easy for them to cling from different surfaces at any orientation with the aid of Van der Waals force as the primary mechanism used to adhere to any contact surfaces. In this paper, a strain simulation using Comsol Multiphysic Software was conducted on a 3D MEMS model of an actuated gecko foot with the aim of achieving optimal sticking with various polymetric materials for future robots application. Based on the stress and strain analyses done on the seven different polymers, it was found that polysilicon had the best result which was nearest to 0%, indicating the strongest elasticity among the others. PDMS on the hand, failed in the simulation due to its bulk-like nature. Thus, PDMS was not suitable to be used for further study on gecko foot robot.

  12. PAST AND FUTURE APPLICATIONS OF 3-D (VIRTUAL REALITY TECHNOLOGY

    Directory of Open Access Journals (Sweden)

    Nigel Foreman

    2014-11-01

    Full Text Available Virtual Reality (virtual environment technology, VET has been widely available for twenty years. In that time, the benefits of using virtual environments (VEs have become clear in many areas of application, including assessment and training, education, rehabilitation and psychological research in spatial cognition. The flexibility, reproducibility and adaptability of VEs are especially important, particularly in the training and testing of navigational and way-finding skills. Transfer of training between real and virtual environments has been found to be reliable. However, input device usage can compromise spatial information acquisition from VEs, and distances in VEs are invariably underestimated. The present review traces the evolution of VET, anticipates future areas in which developments are likely to occur, and highlights areas in which research is needed to optimise usage.

  13. Medical beam monitor—Pre-clinical evaluation and future applications

    Science.gov (United States)

    Frais-Kölbl, Helmut; Griesmayer, Erich; Schreiner, Thomas; Georg, Dietmar; Pernegger, Heinz

    2007-10-01

    Future medical ion beam applications for cancer therapy which are based on scanning technology will require advanced beam diagnostics equipment. For a precise analysis of beam parameters we want to resolve time structures in the range of microseconds to nanoseconds. A prototype of an advanced beam monitor was developed by the University of Applied Sciences Wiener Neustadt and its research subsidiary Fotec in co-operation with CERN RD42, Ohio State University and the Jožef Stefan Institute in Ljubljana. The detector is based on polycrystalline Chemical Vapor Deposition (pCVD) diamond substrates and is equipped with readout electronics up to 2 GHz analog bandwidth. In this paper we present the design of the pCVD-detector system and results of tests performed in various particle accelerator based facilities. Measurements performed in clinical high energy photon beams agreed within 1.2% with results obtained by standard ionization chambers.

  14. Medical beam monitor—Pre-clinical evaluation and future applications

    CERN Document Server

    Frais-Kölbl, H; Schreiner, T; Georg, D; Pernegger, H

    2007-01-01

    Future medical ion beam applications for cancer therapy which are based on scanning technology will require advanced beam diagnostics equipment. For a precise analysis of beam parameters we want to resolve time structures in the range of microseconds to nanoseconds. A prototype of an advanced beam monitor was developed by the University of Applied Sciences Wiener Neustadt and its research subsidiary Fotec in co-operation with CERN RD42, Ohio State University and the Jožef Stefan Institute in Ljubljana. The detector is based on polycrystalline Chemical Vapor Deposition (pCVD) diamond substrates and is equipped with readout electronics up to 2 GHz analog bandwidth. In this paper we present the design of the pCVD-detector system and results of tests performed in various particle accelerator based facilities. Measurements performed in clinical high energy photon beams agreed within 1.2% with results obtained by standard ionization chambers.

  15. Future Translational Applications From the Contemporary Genomics Era

    Science.gov (United States)

    Fox, Caroline S.; Hall, Jennifer L.; Arnett, Donna K.; Ashley, Euan A.; Delles, Christian; Engler, Mary B.; Freeman, Mason W.; Johnson, Julie A.; Lanfear, David E.; Liggett, Stephen B.; Lusis, Aldons J.; Loscalzo, Joseph; MacRae, Calum A.; Musunuru, Kiran; Newby, L. Kristin; O’Donnell, Christopher J.; Rich, Stephen S.; Terzic, Andre

    2016-01-01

    The field of genetics and genomics has advanced considerably with the achievement of recent milestones encompassing the identification of many loci for cardiovascular disease and variable drug responses. Despite this achievement, a gap exists in the understanding and advancement to meaningful translation that directly affects disease prevention and clinical care. The purpose of this scientific statement is to address the gap between genetic discoveries and their practical application to cardiovascular clinical care. In brief, this scientific statement assesses the current timeline for effective translation of basic discoveries to clinical advances, highlighting past successes. Current discoveries in the area of genetics and genomics are covered next, followed by future expectations, tools, and competencies for achieving the goal of improving clinical care. PMID:25882488

  16. Spectral Matrix Filtering Applied to Vsp Processing Application du filtrage matriciel au traitement des profils sismiques verticaux

    Directory of Open Access Journals (Sweden)

    Glangeaud F.

    2006-11-01

    données et de séparer ces signaux. Nous montrons que les signaux peuvent être automatiquement séparés sans connaissance a priori sur leurs vitesses apparentes, en fonction du produit scalaire (calculé dans le domaine fréquentiel et de l'amplitude relative des signaux. Nous montrons des exemples d'application sur des données de sismique de puits. Le filtrage matriciel est effectué dans le domaine fréquentiel en utilisant la matrice spectrale construite à l'aide des intercorrélations des différents enregistrements constituant les données à traiter. Les méthodes d'estimation de la matrice spectrale sont des méthodes de moyenne : moyenne en fréquence (méthode du périodogramme lissé et/ou moyenne en distance (lissage réalisé le long des diagonales de la matrice spectrale. Le lissage en fréquence est obtenu par l'intermédiaire d'une fonction de pondération (par exemple fenêtre de Hanning élevée à une puissance donnée appliquée à chaque corrélation. Les moyennes sont utilisées pour décorréler les signaux et de ce fait favoriser la séparation. Une fois correctement estimée, la matrice spectrale est diagonalisée sur toutes les fréquences du spectre moyenné, et décomposée selon ses vecteurs propres qui sont orthogonaux entre eux et normalisés. Chaque vecteur propre a une valeur propre associée qui représente la répartition d'énergie en fonction de la fréquence du modèle lié au vecteur propre. Le filtrage est réalisé par projection des données sur les différents vecteurs propres issus de la matrice spectrale. Il est à noter cependant que la séparation des différents signaux (projection sur vecteur propre n'est réalisée en terme d'indicatrice sismique que si les événements sismiques sont naturellement orthogonaux et alignés sur les vecteurs propres. Glangeaud et al (1989 ont étudié l'influence des amplitudes relatives et du produit scalaire de deux ondes. Si la vitesse apparente d'une onde est connue, cette derni

  17. Laccase applications in biofuels production: current status and future prospects.

    Science.gov (United States)

    Kudanga, Tukayi; Le Roes-Hill, Marilize

    2014-08-01

    The desire to reduce dependence on the ever diminishing fossil fuel reserves coupled with the impetus towards green energy has seen increased research in biofuels as alternative sources of energy. Lignocellulose materials are one of the most promising feedstocks for advanced biofuels production. However, their utilisation is dependent on the efficient hydrolysis of polysaccharides, which in part is dependent on cost-effective and benign pretreatment of biomass to remove or modify lignin and release or expose sugars to hydrolytic enzymes. Laccase is one of the enzymes that are being investigated not only for potential use as pretreatment agents in biofuel production, mainly as a delignifying enzyme, but also as a biotechnological tool for removal of inhibitors (mainly phenolic) of subsequent enzymatic processes. The current review discusses the major advances in the application of laccase as a potential pretreatment strategy, the underlying principles as well as directions for future research in the search for better enzyme-based technologies for biofuel production. Future perspectives could include synergy between enzymes that may be required for optimal results and the adoption of the biorefinery concept in line with the move towards the global implementation of the bioeconomy strategy.

  18. Aux origines du mot 'transhumanisme'

    OpenAIRE

    Dard, Olivier; Moatti, Alexandre

    2016-01-01

    International audience; Article published in Futuribles.; Ceci est la « version auteur » d'un article publié dans la revue Futuribles n°413, juillet-août 2016. Le sommaire complet du numéro est ici : https://www.futuribles.com/fr/revue/413/ Extrait ci-après :

  19. Modelling and Designing Cryogenic Hydrogen Tanks for Future Aircraft Applications

    Directory of Open Access Journals (Sweden)

    Christopher Winnefeld

    2018-01-01

    Full Text Available In the near future, the challenges to reduce the economic and social dependency on fossil fuels must be faced increasingly. A sustainable and efficient energy supply based on renewable energies enables large-scale applications of electro-fuels for, e.g., the transport sector. The high gravimetric energy density makes liquefied hydrogen a reasonable candidate for energy storage in a light-weight application, such as aviation. Current aircraft structures are designed to accommodate jet fuel and gas turbines allowing a limited retrofitting only. New designs, such as the blended-wing-body, enable a more flexible integration of new storage technologies and energy converters, e.g., cryogenic hydrogen tanks and fuel cells. Against this background, a tank-design model is formulated, which considers geometrical, mechanical and thermal aspects, as well as specific mission profiles while considering a power supply by a fuel cell. This design approach enables the determination of required tank mass and storage density, respectively. A new evaluation value is defined including the vented hydrogen mass throughout the flight enabling more transparent insights on mass shares. Subsequently, a systematic approach in tank partitioning leads to associated compromises regarding the tank weight. The analysis shows that cryogenic hydrogen tanks are highly competitive with kerosene tanks in terms of overall mass, which is further improved by the use of a fuel cell.

  20. Innovative thermal energy harvesting for future autonomous applications

    Science.gov (United States)

    Monfray, Stephane

    2013-12-01

    As communicating autonomous systems market is booming, the role of energy harvesting will be a key enabler. As example, heat is one of the most abundant energy sources that can be converted into electricity in order to power circuits. Harvesting systems that use wasted heat open new ways to power autonomous sensors when the energy consumption is low, or to create systems of power generators when the conversion efficiency is high. The combination of different technologies (low power μ-processors, μ-batteries, radio, sensors...) with new energy harvesters compatible with large varieties of use-cases with allow to address this booming market. Thanks to the conjunction of ultra-low power electronic development, 3D technologies & Systems in Package approaches, the integration of autonomous sensors and electronics with ambient energy harvesting will be achievable. The applications are very wide, from environment and industrial sensors to medical portable applications, and the Internet of things may also represent in the future a several billions units market.

  1. Innovative thermal energy harvesting for future autonomous applications

    International Nuclear Information System (INIS)

    Monfray, Stephane

    2013-01-01

    As communicating autonomous systems market is booming, the role of energy harvesting will be a key enabler. As example, heat is one of the most abundant energy sources that can be converted into electricity in order to power circuits. Harvesting systems that use wasted heat open new ways to power autonomous sensors when the energy consumption is low, or to create systems of power generators when the conversion efficiency is high. The combination of different technologies (low power μ-processors, μ-batteries, radio, sensors...) with new energy harvesters compatible with large varieties of use-cases with allow to address this booming market. Thanks to the conjunction of ultra-low power electronic development, 3D technologies and Systems in Package approaches, the integration of autonomous sensors and electronics with ambient energy harvesting will be achievable. The applications are very wide, from environment and industrial sensors to medical portable applications, and the Internet of things may also represent in the future a several billions units market

  2. Ecologie du phytoplancton du lac Kivu

    Directory of Open Access Journals (Sweden)

    Sarmento, H.

    2008-01-01

    Full Text Available Speciation within the African Coffee Pathogen. Cet article analyse s'il est avantageux d'utiliser le compost au lieu de l'engrais minéral pour produire la laitue dans la zone urbaine et péri-urbaine de Yaoundé. Les résultats de terrain montrent l'obtention de rendements et profits plus élevés lorsqu'on utilise le compost. Les résultats de la fonction de production Cobb-Douglas prouvent que l'utilisation du compost est statistiquement significative pour expliquer la variation de rendement de la laitue et que le compost est l'intrant le plus productif. D'autres résultats montrent que le compost fournit la matière organique utile au sol et que les besoins d'irrigation en eau de la culture sont réduits grâce à l'utilisation du compost. Par conséquent, malgré le fait que l'application du compost demande une main-d'oeuvre beaucoup plus élevée, son utilisation est généralement bénéfique pour les agriculteurs vivant aux alentours de Yaoundé. Les programmes de vulgarisation de cet intrant pour encourager son adoption devraient donc figurer parmi les points prioritaires dans la politique agricole du gouvernement camerounais.

  3. High-sensitivity gamma spectroscopy for extended sources. Application to activity measurements on the human body, on glass, and on soil; Spectrographie gamma a grande sensibilite pour sources etendues. Application a la mesure de l'activite du corps humain, du verre et du sol

    Energy Technology Data Exchange (ETDEWEB)

    Jouve, B

    1962-07-01

    The measurement and location by gamma spectroscopy of human body internal contaminations at maximum permissible levels, and, in certain cases, at lower activities such as that due to {sup 40}K was investigated. The characteristics of the high-sensitivity apparatus used are given, and several assemblies using large-volume NaI(Tl) scintillators are described. The relatively light shielding required for natural radioactivity permitted construction of mobile assembly. Conditions of use are described, and the results are given. All gamma emitting elements were measured in 15 min at levels lower than the tolerance dose. Gamma spectroscopy was also used to determine fission products in the earth and to study radioactive elements in the presence of other emitters. (author) [French] La spectrographie gamma du corps humain permet la mesure et la localisation des contaminations internes au niveau des doses de tolerance et, dans certains cas, celle d'activites plus faibles comme la radioactivite naturelle due principalement au potassium 40. Les caracteristiques des appareils a grande sensibilite permettant ces mesures sont exposees et on decrit plusieurs realisations originales utilisant un scintillateur NaI(Tl) de grand volume. L'epaisseur du blindage a ete limitee a 5 cm de plomb, ainsi, pour une protection suffisante contre les rayonnements ambiants, les appareils sont relativement legers et l'une des realisations a pu etre installee dans un laboratoire mobile. Les conditions d'utilisation (mouvement propre, etalonnage) et les resultats obtenus sont donnes; tous les radioelements emetteurs gamma sont mesurables en 15 minutes a un niveau inferieur a la dose de tolerance. On presente enfin des applications a la spectrographie gamma d'echantillons volumineux (poudres ou liquides) et de tres faible activite: elles interessent des domaines tres varies comme, par exemple, la geophysique (etude des retombees radioactives) ou l'industrie chimique

  4. The Future of Petroleum As an Energy Resource L'avenir du pétrole comme source d'énergie

    Directory of Open Access Journals (Sweden)

    Erdman J. G.

    2006-10-01

    la production d'énergie ne dépasse plus l'énergie dépensée pour la production et l'utilisation. On peut admettre un bilan légèrement négatif dans les cas où des caractéristiques particulières le justifient, et où il y a compensation par un apport d'une source d'énergie moins demandée. Pendant ce siècle, le pétrole est devenu la source préférée d'énergie. Aujourd'hui, aux Etats-Unis, 750 % de l'énergie consommée est dérivée des hydrocarbures. La hausse rapide des prix mondiaux du pétrole est pour la plus grande partie une conséquence de facteurs politiques et économiques. De tels facteurs peuvent forcer certains pays consommateurs à s'orienter vers des énergies de remplacement. A l'échelle mondiale, l'utilisation future du pétrole, dans le temps et en fonction de l'abaissement des réserves, dépendra de la capacité des techniciens à ralentir le rapprochement des courbes de production d'énergie et des dépenses énergétiques de cette production. Pour suivre la trace des succès passés, il faudra développer de nouvelles idées et technologies en exploration, production et utilisation.

  5. Bulletin du CRDI #127

    International Development Research Centre (IDRC) Digital Library (Canada)

    Une application pour téléphone intelligent améliore l'élevage durable du bétail en Éthiopie En Éthiopie, l'élevage et les produits d'élevage contribuent au revenu de 75 % des familles. Cependant, la productivité de ce secteur est parmi la plus basse du continent en raison de l'accès limité aux services vétérinaires.

  6. La pratique du francais assiste par ordinateur (The Application of Computer-Assisted French).

    Science.gov (United States)

    Malandain, Jean-Louis

    1985-01-01

    Language teachers are urged to explore, develop, and use the entire range of applications made possible by the computer and to realize that the computer can do almost anything but generate ideas. (MSE)

  7. X-spectrographic method for plutonium detection. Application to contamination measurements in humans; Etude d'une methode de detection du plutonium par spectrographie X. Application a la mesure des contaminations sur l'homme

    Energy Technology Data Exchange (ETDEWEB)

    Michel Trouble [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    After reviewing the radio-toxicology of plutonium 239 and conventional detection methods using its {alpha}-radiation, the author considers the measurement of the X emission spectrum of plutonium 239 using a proportional counter filled with argon under pressure. This preliminary work leads to the third part of this research involving the detailed study of the possibilities of applying thin alkali halide crystal scintillators to the detection of soft plutonium X-rays; there follows a systematic study of all the parameters liable to render the detection as sensitive as possible: movement due to the photomultiplier itself and its accessory electronic equipment, nature and size of the crystal scintillator as well as its mode of preparation, shielding against external parasitic radiation. Examples of some applications to the measurement of contamination in humans give an idea of the sensitivity of this method. (author) [French] Apres un apercu de la radiotoxicologie du plutonium 239 et des methodes classiques de detection par son rayonnement {alpha}, on etudie le spectre d'emission X du plutonium 239 avec un compteur proportionnel rempli avec de l'argon sous pression. Ce travail preliminaire permet d'aborder la troisieme partie de cette etude dans laquelle nous examinons d'une fagon approfondie les possibilites d'application des cristaux scintillateurs minces d'halogenure alcalin a la detection du rayonnement X mou du plutonium; suit une etude systematique de tous les parametres susceptibles de rendre la detection aussi sensible que possible: mouvement propre du photomultiplicateur et de l'electronique associee, nature et dimensions du cristal scintillateur ainsi que son mode de fabrication, blindage contre les rayonnements parasites exterieurs. Quelques applications a la mesure des contaminations sur l'homme permettent d'apprecier la sensibilite de cette methode. (auteur)

  8. UTILISATION DU MODÈLE ÉCREVISSE COMME ESPÈCE BIOINDICATRICE DE POLLUTION. APPLICATION À L’ÉTUDE DES TRANSFERTS TROPHIQUES DU CADMIUM

    Directory of Open Access Journals (Sweden)

    SIMON O.

    2002-07-01

    Full Text Available La bioaccumulation des métaux par les organismes aquatiques est directement liée aux modalités d’exposition : contamination directe via le milieu ou contamination trophique via l’ingestion de proies contaminées. Pour appréhender les perturbations des écosystèmes, il apparaît important de déterminer des espèces « bioindicatrices » et de mesurer la part respective de ces deux voies d’exposition. Les travaux présentés concernent le transfert trophique du cadmium entre une proie, le bivalve benthique Corbicula fluminea, et un de ses prédateurs, l’écrevisse Astacus astacus. Afin d’insister sur l’importance des modalités de prédation de ce crustacé, nous avons réalisé 2 approches expérimentales complémentaires. La première concerne la consommation « naturelle » de proies contaminées pendant 30 jours d’exposition, la seconde consiste à introduire directement un bol alimentaire de proies contaminées dans l’estomac des écrevisses par une technique de gavage. Les résultats montrent une différence importante entre ces deux approches expérimentales.

  9. 20. Les transports du futur

    OpenAIRE

    Battin-Leclerc, Frédérique

    2017-01-01

    Les transports contribuent de façon significative à la consommation de pétrole et à l’émission dans l’atmosphère de gaz polluants. La combustion des carburants dans les moteurs conduit, en particulier, à la formation de gaz à effet de serre*, principalement de dioxyde de carbone (CO2) dont les émissions au niveau mondial sont en constante augmentation. Les moteurs sont aussi responsables de la formation de composés toxiques, soit directement, comme les aldéhydes* ou les particules de suies, s...

  10. Le futur du project LHC

    CERN Multimedia

    Heyoka

    2007-01-01

    Since 2004, and specitally during the long study in 2005, we used the results of the LHC Project to evaluate differents parameters of the machiene (LHC). The final choices for the design of the machine are based partly on these results. (1,5 page)

  11. La notion de zone de connexion biologique. Son application en aménagement du territoire

    Directory of Open Access Journals (Sweden)

    Philippe Ménard

    2001-12-01

    Full Text Available La notion de zone de connexion biologique a été définie comme un espace fonctionnel d'échange biologique permettant le maintien des biodiversités locales. Nous avons testé son intérêt et son application dans le cas d'un paysage complexe très fragmenté, traversé par un projet autoroutier.

  12. Chagas Disease Diagnostic Applications: Present Knowledge and Future Steps.

    Science.gov (United States)

    Balouz, V; Agüero, F; Buscaglia, C A

    2017-01-01

    Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating illness of major significance throughout Latin America and an emergent threat to global public health. Being a neglected disease, the vast majority of Chagasic patients have limited access to proper diagnosis and treatment, and there is only a marginal investment into R&D for drug and vaccine development. In this context, identification of novel biomarkers able to transcend the current limits of diagnostic methods surfaces as a main priority in Chagas disease applied research. The expectation is that these novel biomarkers will provide reliable, reproducible and accurate results irrespective of the genetic background, infecting parasite strain, stage of disease, and clinical-associated features of Chagasic populations. In addition, they should be able to address other still unmet diagnostic needs, including early detection of congenital T. cruzi transmission, rapid assessment of treatment efficiency or failure, indication/prediction of disease progression and direct parasite typification in clinical samples. The lack of access of poor and neglected populations to essential diagnostics also stresses the necessity of developing new methods operational in point-of-care settings. In summary, emergent diagnostic tests integrating these novel and tailored tools should provide a significant impact on the effectiveness of current intervention schemes and on the clinical management of Chagasic patients. In this chapter, we discuss the present knowledge and possible future steps in Chagas disease diagnostic applications, as well as the opportunity provided by recent advances in high-throughput methods for biomarker discovery. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Chagas disease diagnostic applications: present knowledge and future steps

    Science.gov (United States)

    Balouz, Virginia; Agüero, Fernán; Buscaglia, Carlos A.

    2017-01-01

    Chagas disease, caused by the protozoan Trypanosoma cruzi, is a life-long and debilitating illness of major significance throughout Latin America, and an emergent threat to global public health. Being a neglected disease, the vast majority of Chagasic patients have limited access to proper diagnosis and treatment, and there is only a marginal investment into R&D for drug and vaccine development. In this context, identification of novel biomarkers able to transcend the current limits of diagnostic methods surfaces as a main priority in Chagas disease applied research. The expectation is that these novel biomarkers will provide reliable, reproducible and accurate results irrespective of the genetic background, infecting parasite strain, stage of disease, and clinical-associated features of Chagasic populations. In addition, they should be able to address other still unmet diagnostic needs, including early detection of congenital T. cruzi transmission, rapid assessment of treatment efficiency or failure, indication/prediction of disease progression and direct parasite typification in clinical samples. The lack of access of poor and neglected populations to essential diagnostics also stress the necessity of developing new methods operational in Point-of-Care (PoC) settings. In summary, emergent diagnostic tests integrating these novel and tailored tools should provide a significant impact on the effectiveness of current intervention schemes and on the clinical management of Chagasic patients. In this chapter, we discuss the present knowledge and possible future steps in Chagas disease diagnostic applications, as well as the opportunity provided by recent advances in high-throughput methods for biomarker discovery. PMID:28325368

  14. Futurism.

    Science.gov (United States)

    Foy, Jane Loring

    The objectives of this research report are to gain insight into the main problems of the future and to ascertain the attitudes that the general population has toward the treatment of these problems. In the first section of this report the future is explored socially, psychologically, and environmentally. The second section describes the techniques…

  15. Contribution à l'utilisation de sous-produits industriels : application au cas du phosphogypse de Sfax ( Tunisie)

    OpenAIRE

    Rouis, Badreddine

    1991-01-01

    Le travail exposé dans ce mémoire est une approche pour la réutilisation d'un sous produit industriel: Le PHOSPHOGYPSE. Nous avons commencé par un rappel du cadre géo-politique de cette étude en précisant l'origine du matériau, son mode de stockage et son incidence sur l'environnement de la ville de SFAX (Tunisie). En deuxième partie, nous avons étudié la possibilité de l'utilisation du phosphogypse en remblai en effectuant une série d'essais géotechniques dont le paramètre principal est la t...

  16. Future developments and applications of nitrogen-bearing steels ...

    Indian Academy of Sciences (India)

    Abstract. After considerations related with the global frame of the demand of society in the field of materials and some recalling of basic properties and principles of nitrogen alloying, possible future developments are listed and discussed.

  17. The application of future workshops in a healthcare setting

    DEFF Research Database (Denmark)

    Sørensen, Natasha Lee; Johansen, Simon Kristoffer; Hansen, Louise

    Introduction: The future workshop (FW) is a method designed in the seventies by the Austrian Robert Jungk, and developed to create visions for the future in a problem-solving process. Initially, FW was applied as a tool in a political context to create social fantasies, and recently, FW has been...... part to form three groups, and the other for orthopaedic surgery (March 13th), where nine participants took part to also form three groups. Both FW achieved the desired aim of creating visions in a problem-solving process and audio was recorded with the purpose of future investigation through...... surgeons and general practitioners on the use of PRO within hip/knee OA suggests that FW may be used for elicitation of knowledge in a healthcare setting in the future....

  18. Ferroelectric thin films for future thermonuclear reactor diagnostic applications

    International Nuclear Information System (INIS)

    Zauls, V.; Kundzins, K.; Aulika, I.; Kundzins, M.; Stenbergs, A.

    2006-01-01

    Full text: General overview of active material selection requirements for use in bolometric radiation diagnostics systems of future nuclear fusion reactors in comparison with our results of ferroelectric material based elements will be presented. Under modulated thermal irradiation bolometric sensitivity with the range of few mili-Kelvin temperature resolution at 0,2 s time response constant has been demonstrated by thin ferroelectric film capacitive sensor model on thick substrate. Sample measurement system has been developed to be compatible with Wheatstone bridge type bolometric heads measurement concept of ASDEX or ToreSupra reactor sites for future tests

  19. Membrane technology applications in the food industry: Present and future

    Energy Technology Data Exchange (ETDEWEB)

    Leeper, S.A.; Mohr, C.M.; Engelgau, D.E.; Charboneau, B.L.

    1990-01-01

    This presentation provides an overview of present, near-term, and potential applications of membrane technology in the food industry. This presentation is based on a comprehensive survey of membrane applications and research in the food industry prepared by EG G Idaho, Inc. for the US Department of Energy, Office of Industrial Programs. 2 refs., 3 tabs.

  20. Robotics, Artificial Intelligence, Computer Simulation: Future Applications in Special Education.

    Science.gov (United States)

    Moore, Gwendolyn B.; And Others

    The report describes three advanced technologies--robotics, artificial intelligence, and computer simulation--and identifies the ways in which they might contribute to special education. A hybrid methodology was employed to identify existing technology and forecast future needs. Following this framework, each of the technologies is defined,…

  1. Present and future applications of analogue microwave photonics

    DEFF Research Database (Denmark)

    Tafur Monroy, Idelfonso

    2009-01-01

    Photonics may be even more suited for analog than for digital signal applications. Today, microwave photonics techniques are currently used in radio-over-fibre signal transmission and other commercial applications, but recent advances are widening the scope of application to new areas. The speakers...... will introduce present and emerging opportunities for analog photonics, among which microwave filters, arbitrary optical waveform control, THz radiation and UWB pulse generation. A panel discussion will contrast different views from company, academy and funding bodies, to identify the most promising ones...

  2. Physically unclonable functions (PUFs) applications, models, and future directions

    CERN Document Server

    Wachsmann, Christian

    2014-01-01

    Today, embedded systems are used in many security-critical applications, from access control, electronic tickets, sensors, and smart devices (e.g., wearables) to automotive applications and critical infrastructures. These systems are increasingly used to produce and process both security-critical and privacy-sensitive data, which bear many security and privacy risks. Establishing trust in the underlying devices and making them resistant to software and hardware attacks is a fundamental requirement in many applications and a challenging, yet unsolved, task. Solutions solely based on software ca

  3. Industrial applications of enzyme biocatalysis: Current status and future aspects.

    Science.gov (United States)

    Choi, Jung-Min; Han, Sang-Soo; Kim, Hak-Sung

    2015-11-15

    Enzymes are the most proficient catalysts, offering much more competitive processes compared to chemical catalysts. The number of industrial applications for enzymes has exploded in recent years, mainly owing to advances in protein engineering technology and environmental and economic necessities. Herein, we review recent progress in enzyme biocatalysis, and discuss the trends and strategies that are leading to broader industrial enzyme applications. The challenges and opportunities in developing biocatalytic processes are also discussed. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Nuclear model developments in FLUKA for present and future applications

    Directory of Open Access Journals (Sweden)

    Cerutti Francesco

    2017-01-01

    Full Text Available The FLUKAS code [1–3] is used in research laboratories all around the world for challenging applications spanning a very wide range of energies, projectiles and targets. FLUKAS is also extensively used for in hadrontherapy research studies and clinical planning systems. In this paper some of the recent developments in the FLUKAS nuclear physics models of relevance for very different application fields including medical physics are presented. A few examples are shown demonstrating the effectiveness of the upgraded code.

  5. Nuclear model developments in FLUKA for present and future applications

    Science.gov (United States)

    Cerutti, Francesco; Empl, Anton; Fedynitch, Anatoli; Ferrari, Alfredo; Ruben, GarciaAlia; Sala, Paola R.; Smirnov, George; Vlachoudis, Vasilis

    2017-09-01

    The FLUKAS code [1-3] is used in research laboratories all around the world for challenging applications spanning a very wide range of energies, projectiles and targets. FLUKAS is also extensively used for in hadrontherapy research studies and clinical planning systems. In this paper some of the recent developments in the FLUKAS nuclear physics models of relevance for very different application fields including medical physics are presented. A few examples are shown demonstrating the effectiveness of the upgraded code.

  6. Future trends in fracture mechanics: theory and applications

    International Nuclear Information System (INIS)

    Hosbons, R.R.

    1978-05-01

    A brief description of the current methods available for the analysis of fracture in ductile materials is given. Crack-opening displacement, R-curves and J-integrals are discussed and their future incorporation into structural codes assessed. The current areas of research which will probably influence code making bodies are also described. Emphasis is made on J-integral theory and a description of its limitations and extensions. Numerical techniques for calculating J for complicated structure are outlined. (author)

  7. Carbon The Future Material for Advanced Technology Applications

    CERN Document Server

    Messina, Giacomo

    2006-01-01

    Carbon-based materials and their applications constitute a burgeoning topic of scientific research among scientists and engineers attracted from diverse areas such as applied physics, materials science, biology, mechanics, electronics and engineering. Further development of current materials, advances in their applications, and discovery of new forms of carbon are the themes addressed by the frontier research in these fields. This book covers all the fundamental topics concerned with amorphous and crystalline C-based materials, such as diamond, diamond-like carbon, carbon alloys, carbon nanotubes. The goal is, by coherently progressing from growth - and characterisation techniques to technological applications for each class of material, to fashion the first comprehensive state-of-the-art review of this fast evolving field of research in carbon materials.

  8. VSAT network applications and services - Present and future

    Science.gov (United States)

    Lorent, Philippe

    This paper gives information on the VSAT network applications and services that can be expected especially in European countries. After general considerations, the situation of VSATs in USA is summarized with reference to the evolution of telecommunications organization in this country. The situation in Europe is different. The purpose of this paper is to present what could be the application field for VSATs in Europe and identify the niches where VSAT network are particularly adapted to the customer requirements. Examples are given as illustrations.

  9. Spéciation du cadmium, du chrome, du cuivre et du plomb dans les ...

    African Journals Online (AJOL)

    L'exploitation du minerai de phosphate au sud-est du Togo engendre des déchets miniers qui sont déversés dans la mer sans traitement. Cette étude a pour but l'estimation de la biodisponibilité du cadmium, du chrome, du cuivre et du plomb par leur spéciation. La caractérisation physicochimique des sédiments des ...

  10. Robotics, Artificial Intelligence, Computer Simulation: Future Applications in Special Education.

    Science.gov (United States)

    Moore, Gwendolyn B.; And Others

    1986-01-01

    Describes possible applications of new technologies to special education. Discusses results of a study designed to explore the use of robotics, artificial intelligence, and computer simulations to aid people with handicapping conditions. Presents several scenarios in which specific technological advances may contribute to special education…

  11. Digital Light Processing update: status and future applications

    Science.gov (United States)

    Hornbeck, Larry J.

    1999-05-01

    Digital Light Processing (DLP) projection displays based on the Digital Micromirror Device (DMD) were introduced to the market in 1996. Less than 3 years later, DLP-based projectors are found in such diverse applications as mobile, conference room, video wall, home theater, and large-venue. They provide high-quality, seamless, all-digital images that have exceptional stability as well as freedom from both flicker and image lag. Marked improvements have been made in the image quality of DLP-based projection display, including brightness, resolution, contrast ratio, and border image. DLP-based mobile projectors that weighted about 27 pounds in 1996 now weight only about 7 pounds. This weight reduction has been responsible for the definition of an entirely new projector class, the ultraportable. New applications are being developed for this important new projection display technology; these include digital photofinishing for high process speed minilab and maxilab applications and DLP Cinema for the digital delivery of films to audiences around the world. This paper describes the status of DLP-based projection display technology, including its manufacturing, performance improvements, and new applications, with emphasis on DLP Cinema.

  12. Phosphorene and Phosphorene-Based Materials - Prospects for Future Applications.

    Science.gov (United States)

    Batmunkh, Munkhbayar; Bat-Erdene, Munkhjargal; Shapter, Joseph G

    2016-10-01

    Phosphorene, a single- or few-layered semiconductor material obtained from black phosphorus, has recently been introduced as a new member of the family of two-dimensional (2D) layered materials. Since its discovery, phosphorene has attracted significant attention, and due to its unique properties, is a promising material for many applications including transistors, batteries and photovoltaics (PV). However, based on the current progress in phosphorene production, it is clear that a lot remains to be explored before this material can be used for these applications. After providing a comprehensive overview of recent advancements in phosphorene synthesis, advantages and challenges of the currently available methods for phosphorene production are discussed. An overview of the research progress in the use of phosphorene for a wide range of applications is presented, with a focus on enabling important roles that phosphorene would play in next-generation PV cells. Roadmaps that have the potential to address some of the challenges in phosphorene research are examined because it is clear that the unprecedented chemical, physical and electronic properties of phosphorene and phosphorene-based materials are suitable for various applications, including photovoltaics. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Heat pumping technologies in Sri Lanka: applications and future prospects

    Energy Technology Data Exchange (ETDEWEB)

    Tharumaratnam, V.; Mendis, D.L.O. [Mini Well Systems (pvt) Ltd. (Sri Lanka)

    1998-09-01

    New applications of heat pumping technologies have been introduced in Sri Lanka. These include manufacture of made tea, drying fruits and vegetables, and drying coconut for manufacture of export quality copra. Tea has been the backbone of the export economy for many years, and only recently has it been overtaken by garment exports. It also accounts for a large amount of energy, in terms of electricity supplied from the national grid, biomass in the form of firewood, and petroleum products , chiefly diesel oil. It has been demonstrated in pilot scale commercial trials by the company that application of heat pumping technology reduces the cost of energy in manufacture of tea from about Rs 5 per kilogram of made tea to about Rs 3. Mobile drying units have been manufactured to demonstrate the application of heat pumping technology for drying fruits, vegetables and other agricultural produce on a commercial scale. This has resulted in considerable interest in the CISIR, the Industrial Development Board, and various private sector organizations. Application of heat pumping to drying coconut for manufacture of copra has been very successful. The quality of copra has been consistently supra-grade, since there is no contamination as in the traditional method of manufacture using biomass fuels in the form of coconut shells, which causes discolouration. (author)

  14. Nanoparticles in medical applications – a direction of the future?

    Directory of Open Access Journals (Sweden)

    Anna Jung

    2014-06-01

    Full Text Available Methods of producing nanoparticles, called nanotechnologies, have inspired lively interest over the recent years due to the broad possibilities for application of nanoparticles in numerous fields, including electronics, information technology, biotechnology, medicine, pharmacy, cosmetology and others. Nanoparticles are defined as particles which may occur in various shapes and which have at least one dimension smaller than 100 nm. Depending on the process of creation we can differentiate between natural nanoparticles occurring in the environment and designed nanoparticles, which are man-made. Designed nanoparticles are characterised by special physical properties which make them suitable for biomedical applications, among others. An example of such an application is the use of silver nanocomposites, which in a micronised form display a strong bacteriostatic and bactericidal effect. Graphene, the latest achievement of nanotechnology with unique mechanical and physical properties, is another material which raises much interest among researchers. The dynamic development of numerous directions in modern technologies based on nanotechnologies is an indisputable sign of progress. The discovery of the unique properties of nanomaterials opens wide possibilities for numerous applications; however, it also requires comprehensive research to ensure they are safe to use.

  15. Plant cell engineering: current research, application and future prospects

    International Nuclear Information System (INIS)

    Wang Xunqing; Liu Luxiang

    2008-01-01

    This paper reviewed the current status of basic research in plant cell engineering, highlighted the application of embryo culture, double haploid (DH) technology, protoplast culture and somatic hybridization, somaclonal variation, rapid propagation, and bio-products production of plant-origin, and t he prospects. (authors)

  16. Nanomedicines for renal disease: current status and future applications

    DEFF Research Database (Denmark)

    Kamaly, Nazila; He, John C.; Ausiello, Dennis A.

    2016-01-01

    Treatment and management of kidney disease currently presents an enormous global burden, and the application of nanotechnology principles to renal disease therapy, although still at an early stage, has profound transformative potential. The increasing translation of nanomedicines to the clinic, a...

  17. Fulas: high energy laser source for future lidar applications

    Science.gov (United States)

    Hahn, S.; Weimer, P.; Wuehrer, Christian; Klein, J.; Luttmann, J.; Plum, H. D.

    2017-11-01

    For atmospheric LIDAR instruments in space, a manifold of scientific applications exists. But due to the lack of high energy laser sources providing the performance, reliability and lifetime necessary to operate such instruments in space, realization is currently seen as still very critical in the community.

  18. Potential diagnostic applications of biosensors: current and future directions

    OpenAIRE

    Song, Shiping; Xu, Hui; Fan, Chunhai

    2006-01-01

    This review describes recent advances in biosensors of potential clinical applications. Biosensors are becoming increasingly important and practical tools in pathogen detection, molecular diagnostics, environmental monitoring, food safety control as well as in homeland defense. Electrochemical biosensors are particularly promising toward these goals arising due to several combined advantages including low-cost, operation convenience, and miniaturized devices. We review the clinical applicatio...

  19. Industry approach to BE applications - Past and future

    International Nuclear Information System (INIS)

    Martin, R.P.

    2004-01-01

    With each passing year the nuclear industry, like all private industry, becomes more reliant on computer-based analysis tools. While this is primarily driven by competition and the natural advancement of computing power, computer analysis tools are also an excellent way to capture engineering know-how. As the average age of nuclear industry personnel approaches 50 years, this becomes increasingly important. The engineers that are retiring today have witnessed a remarkable evolution of computational tools during their tenure. For some, it is the difference between a pencil-and slide- rule and a desktop supercomputer. A curious aspect of this evolution is the question How has industry capitalized on all this advancement? Of course, the answer depends on who is being asked. Part of the answer must come from a historical review. This paper takes an engineer's approach to assessing history. In contrast, a mathematician's approach might be to look at where we have started and where we are today and fit a plausible story to the data. Engineers, on the other hand, have to consider other motivations. Webster Dictionary defines engineering as the application of scientific and mathematical principles to practical ends such as the design, manufacture, and operation of efficient and economical structures, machines, processes, and systems. Clearly, the engineers approach to any problem begins with science and math. The key difference to how an engineer approaches a problem is that 'practical', 'efficient', and 'economical' are on equal footing with 'scientific and mathematical principles'. Basically, engineers go through the same 'curve fitting' approach to every problem, but include more unknowns. Hence, the standard engineers' model is y = C 1 (science) + C 2 (math) + C 3 (practicality) + C 4 (efficiency) C 5 (economics). Computer codes used in the nuclear industry represent a broad spectrum of engineering applications including computer-aided design, structural and mechanical

  20. Military applications of the laser weapons in the future battlefield

    Science.gov (United States)

    Celik, Hasan; Adana, Saban; Yahsi, Erhan

    2013-05-01

    Contemporary operating environment requires a wide range of tools to respond to a myriad of regular and irregular threats. Accordingly, conventional weapons do not suffice in some cases. As technology improves exponentially, the dominance of conventional weapons is slowly fading away by the advances in laser technology. This study first outlines the characteristics of laser weapons, then provides the military applications of them in land, maritime, air and space domains and finally exhibits implications for battlefield functions. This study concludes that any country that is seeking primacy in military terms must allocate extra time and resources to obtain this emerging technology. Since it seems that there are not adequate studies about the military applications and operational concepts of the laser weapons, this study tries to increase awareness about their potential advantages.

  1. Future developments in laser technology and their applications

    International Nuclear Information System (INIS)

    Boyer, K.

    1979-01-01

    One of the many areas in which lasers are beginning to play an important role is that of chemistry. One application of great significance is the use of low average power tunable lasers as an analytical tool to measure or study reaction kinetics and products. The other application of equal or greater importance is the use of high average power tunable lasers as a manipulative tool to control or drive chemical reactions in industrial processes. Here the cost of photons is the most important factor and a new device called the 'Free Electron Laser' is under development which promises to reduce the photon cost to less than one dollar per pound of material, thus including a wide range of industrial products

  2. Current Applications and Future Prospects of Stem Cells in Dentistry.

    Science.gov (United States)

    Surendran, Sharmila; Sivamurthy, Gautham

    2015-01-01

    Stem cells are defined as clonogenic, unspecialized cells capable of both selt-renewal and multi-lineage differentiation, contributing to regenerating specific tissues. For years, restorative treatments have exploited the lifelong regenerative potential of dental pulp stem cells to give rise to tertiary dentine, which is therapeutically employed for direct and indirect pulp capping. Current applications of stem cells in endodontic research have revealed their potential to continue root development in necrotic immature teeth and transplanted/replanted teeth. Successful application of pulp revascularization is highlighted here with support of a clinical case report. This article also discusses the role of dental stem cells as a promising tool for regeneration of individual tissue types like dentine, pulp and even an entire functional tooth.

  3. 3-D transponder antennas for future SHF RFID applications

    Science.gov (United States)

    Zichner, R.; Baumann, R. R.

    2011-12-01

    The radio frequency identification (RFID) technology is omnipresent since a few years. Some of the most popular fields of application are the use for security tasks, for logistics and for the consumer segment. For example, chip card or key ring sized RFID transponders can allow wireless access to secured rooms. The number of applications for wireless data transmission for the identification and tracking of objects increases every year. There is a large development need for highly functional and inexpensive RFID transponders due to the ever-increasing demand on improved reliability, higher data rates and read and write ranges of the RFID systems. Therefore, research was performed on new 3-D transponder antennas for the Super High Frequency Band around 5.8 GHz. Additionally, wave propagation effects and the influence of different dielectric environments were considered. Parallel to the design of the novel antenna structures, the printing process for inexpensive manufacturing was investigated. The gained results are the basis for prospective RFID applications.

  4. Health Physics Innovations Developed During Cassini for Future Space Applications

    Science.gov (United States)

    Nickell, Rodney E.; Rutherford, Theresa M.; Marmaro, George M.

    1999-01-01

    The long history of space flight includes missions that used Space Nuclear Auxiliary Power devices, starting with the Transit 4A Spacecraft (1961), continuing through the Apollo, Pioneer, Viking, Voyager, Galileo, Ulysses, Mars Pathfinder, and most recently, Cassini (1997). All Major Radiological Source (MRS) missions were processed at Kennedy Space Center/Cape Canaveral Air Station (KSC/CCAS) Launch Site in full compliance with program and regulatory requirements. The cumulative experience gained supporting these past missions has led to significant innovations which will be useful for benchmarking future MRS mission ground processing. Innovations developed during ground support for the Cassini mission include official declaration of sealed-source classifications, utilization of a mobile analytical laboratory, employment of a computerized dosimetry record management system, and cross-utilization of personnel from related disciplines.

  5. Application de l'A.D.L, pour la mesure du champ de vitesses instationnaires de llecoulement a Ilechappement d'un moteur a combustion interne

    Science.gov (United States)

    Boutrif, M. S.; Thelliez, M.

    1993-01-01

    We present experimental results of instantaneous velocity measurement, which were obtained by application of the laser Doppler anemometry (L.D.A.) at the exhaust pipe of a reciprocating engine under real working conditions. First of all, we show that the instantaneous velocity is monodimensional along a straight exhaust pipe, and that the boundary layer develops within a 2mm thickness. We also show that the cylinder discharges in two phases : the blow down period and the final part of exhaust stroke. We also make obvious, that the flow escapes very quickly : its velocity varies between - 100m/s and 200m/s within a period shorter than 1ms ; thereby, we do record the acoustic resonance phenomenon, when the engine speed is greater than 3 000rpm. Finally, we show that in the exhaust pipe the apparent fluctuation - i.e. the cyclic dispersion and the actual turbulence - may reach 15%. Nous présentons des résultats expérimentaux du champ de vitesses instationnaires, obtenus par adaptation et application de la vélocimétrie laser interférentielle communément appelée à effet Doppler (L.D.A.), à l'échappement d'un moteur altematif à combustion inteme en fonctionnement nominal. Tout d'abord, nous montrons que dans un tube d'échappement long et droit, la vitesse instantanée est bien monodimensionnelle et que l'écoulement occupe la quasitotalité de la section droite géométrique du tube (une couche limite d'épaisseur inférieure à 2mm se développe très près de la paroi du tube). Nous pouvons également décrire la vidange du cylindre du moteur étudié en deux phases principales : bouffée d'échappement et refoulement des gaz brûlés par le piston. Nous mettons de même en évidence l'état très pulsé de l'écoulement, puisqu'en un intervalle de temps inférieur à 1ms, la vitesse de l'écoulement varie de - 100m/s à 200m/s ; nous enregistrons ainsi l'apparition du phénomène de résonance acoustique à des vitesses de rotation supérieures à 3 500

  6. FUTURES

    DEFF Research Database (Denmark)

    Pedersen, Michael Haldrup

    2017-01-01

    Currently both design thinking and critical social science experience an increased interest in speculating in alternative future scenarios. This interest is not least related to the challenges issues of global sustainability present for politics, ethics and design. This paper explores the potenti......Currently both design thinking and critical social science experience an increased interest in speculating in alternative future scenarios. This interest is not least related to the challenges issues of global sustainability present for politics, ethics and design. This paper explores...... the potentials of speculative thinking in relation to design and social and cultural studies, arguing that both offer valuable insights for creating a speculative space for new emergent criticalities challenging current assumptions of the relations between power and design. It does so by tracing out discussions...... of ‘futurity’ and ‘futuring’ in design as well as social and cultural studies. Firstly, by discussing futurist and speculative approaches in design thinking; secondly by engaging with ideas of scenario thinking and utopianism in current social and cultural studies; and thirdly by showing how the articulation...

  7. The gammaTuRC Nanomachine Mechanism and Future Applications

    Science.gov (United States)

    Riehlman, Timothy D.

    The complexity and precision of the eukaryotic cell's cytoskeletal network is unrivaled by any man-made systems, perfected by billions of years of evolution, mastering elegant processes of self-assembly, error correction, and self-repair. Understanding the capabilities of these networks will have important and far reaching applications in human medicine by aiding our understanding of developmental processes, cellular division, and disease mechanisms, and through biomimicry will provide insights for biosynthetic manufacturing at the nanoscale and across scales. My research utilizes cross species techniques from Human to the model organism of Fission Yeast to investigate the structure and mechanisms of the g-tubulin ring complex (gTuRC). The gTuRC is a highly conserved eukaryotic multiprotein complex serving as a microtubule organizing center (MTOC) responsible for microtubule nucleation through templating, regulation of dynamics, and establishment of microtubule polarity. Microtubules are 25 nm diameter dynamic flexible polymers of a/b-tubulin heterodimers that function as scaffolds, force generators, distributors, and intracellular highways. The microtubule cytoskeleton is essential for numerous fundamental cellular processes such as mitotic division of chromosomes and cell division, organelle distribution within the cell, cell signaling, and cell shape. This incredible diversity in functions is made possible in part due to molecular motor Kinesin-like proteins (Klps), which allow expansion into more specialized neural, immune, and ciliated cell functions. Combined, the MTOC, microtubules, and Klps represent ideal microtubule cytoskeleton protein (MCP) modular components for in vitro biomimicry towards generation of adaptable patterned networks for human designed applications. My research investigates the hypothesis that a mechanistic understanding of conserved MTOC gTuRC mechanisms will help us understand dynamic cellular nanomachines and their ability to self

  8. Machine learning for epigenetics and future medical applications.

    Science.gov (United States)

    Holder, Lawrence B; Haque, M Muksitul; Skinner, Michael K

    2017-07-03

    Understanding epigenetic processes holds immense promise for medical applications. Advances in Machine Learning (ML) are critical to realize this promise. Previous studies used epigenetic data sets associated with the germline transmission of epigenetic transgenerational inheritance of disease and novel ML approaches to predict genome-wide locations of critical epimutations. A combination of Active Learning (ACL) and Imbalanced Class Learning (ICL) was used to address past problems with ML to develop a more efficient feature selection process and address the imbalance problem in all genomic data sets. The power of this novel ML approach and our ability to predict epigenetic phenomena and associated disease is suggested. The current approach requires extensive computation of features over the genome. A promising new approach is to introduce Deep Learning (DL) for the generation and simultaneous computation of novel genomic features tuned to the classification task. This approach can be used with any genomic or biological data set applied to medicine. The application of molecular epigenetic data in advanced machine learning analysis to medicine is the focus of this review.

  9. Adaptive coded aperture imaging: progress and potential future applications

    Science.gov (United States)

    Gottesman, Stephen R.; Isser, Abraham; Gigioli, George W., Jr.

    2011-09-01

    Interest in Adaptive Coded Aperture Imaging (ACAI) continues to grow as the optical and systems engineering community becomes increasingly aware of ACAI's potential benefits in the design and performance of both imaging and non-imaging systems , such as good angular resolution (IFOV), wide distortion-free field of view (FOV), excellent image quality, and light weight construct. In this presentation we first review the accomplishments made over the past five years, then expand on previously published work to show how replacement of conventional imaging optics with coded apertures can lead to a reduction in system size and weight. We also present a trade space analysis of key design parameters of coded apertures and review potential applications as replacement for traditional imaging optics. Results will be presented, based on last year's work of our investigation into the trade space of IFOV, resolution, effective focal length, and wavelength of incident radiation for coded aperture architectures. Finally we discuss the potential application of coded apertures for replacing objective lenses of night vision goggles (NVGs).

  10. Aggregate Interview Method of ranking orthopedic applicants predicts future performance.

    Science.gov (United States)

    Geissler, Jacqueline; VanHeest, Ann; Tatman, Penny; Gioe, Terence

    2013-07-01

    This article evaluates and describes a process of ranking orthopedic applicants using what the authors term the Aggregate Interview Method. The authors hypothesized that higher-ranking applicants using this method at their institution would perform better than those ranked lower using multiple measures of resident performance. A retrospective review of 115 orthopedic residents was performed at the authors' institution. Residents were grouped into 3 categories by matching rank numbers: 1-5, 6-14, and 15 or higher. Each rank group was compared with resident performance as measured by faculty evaluations, the Orthopaedic In-Training Examination (OITE), and American Board of Orthopaedic Surgery (ABOS) test results. Residents ranked 1-5 scored significantly better on patient care, behavior, and overall competence by faculty evaluation (Porthopedic resident candidates who scored highly on the Accreditation Council for Graduate Medical Education resident core competencies as measured by faculty evaluations, performed above the national average on the OITE, and passed the ABOS part 1 examination at rates exceeding the national average. Copyright 2013, SLACK Incorporated.

  11. Chitinases from Bacteria to Human: Properties, Applications, and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Abhishek Singh Rathore

    2015-01-01

    Full Text Available Chitin is the second most plenteous polysaccharide in nature after cellulose, present in cell walls of several fungi, exoskeletons of insects, and crustacean shells. Chitin does not accumulate in the environment due to presence of bacterial chitinases, despite its abundance. These enzymes are able to degrade chitin present in the cell walls of fungi as well as the exoskeletons of insect. They have shown being the potential agents for biological control of the plant diseases caused by various pathogenic fungi and insect pests and thus can be used as an alternative to chemical pesticides. There has been steady increase in demand of chitin derivatives, obtained by action of chitinases on chitin polymer for various industrial, clinical, and pharmaceutical purposes. Hence, this review focuses on properties and applications of chitinases starting from bacteria, followed by fungi, insects, plants, and vertebrates. Designing of chitinase by applying directed laboratory evolution and rational approaches for improved catalytic activity for cost-effective field applications has also been explored.

  12. Multi-Sensor Data Fusion for Future Telematics Application

    Directory of Open Access Journals (Sweden)

    Seong-Baek Kim

    2003-12-01

    Full Text Available In this paper, we present multi-sensor data fusion for telematics application. Successful telematics can be realized through the integration of navigation and spatial information. The well-determined acquisition of vehicle's position plays a vital role in application service. The development of GPS is used to provide the navigation data, but the performance is limited in areas where poor satellite visibility environment exists. Hence, multi-sensor fusion including IMU (Inertial Measurement Unit, GPS (Global Positioning System, and DMI (Distance Measurement Indicator is required to provide the vehicle's position to service provider and driver behind the wheel. The multi-sensor fusion is implemented via algorithm based on Kalman Filtering technique. Navigation accuracy can be enhanced using this filtering approach. For the verification of fusion approach, land vehicle test was performed and the results were discussed. Results showed that the horizontal position errors were suppressed around 1 meter level accuracy under simulated Non-GPS availability environment. Under normal GPS environment, the horizontal position errors were under 40 cm in curve trajectory and 27cm in linear trajectory, which are definitely depending on vehicular dynamics.

  13. Carbon Nanotube Membranes: Synthesis, Properties, and Future Filtration Applications

    Directory of Open Access Journals (Sweden)

    Md. Harun-Or Rashid

    2017-05-01

    Full Text Available Over the course of the past decade, there has been growing interest in the development of different types of membranes composed of carbon nanotubes (CNTs, including buckypapers and composite materials, for an ever-widening range of filtration applications. This article provides an overview of how different types of CNT membranes are prepared and the results obtained from investigations into their suitability for different applications. The latter involve the removal of small particles from air samples, the filtration of aqueous solutions containing organic compounds and/or bacteria, and the separation of individual liquids present in mixtures. A growing number of reports have demonstrated that the incorporation of CNTs into composite membranes confers an improved resistance to fouling caused by biomacromolecules and bacteria. These results are discussed, along with evidence that demonstrates it is possible to further reduce fouling by taking advantage of the inherent conductivity of composite membranes containing CNTs, as well as by using different types of electrochemical stimuli.

  14. HPC Application Performance and Scaling: Understanding Trends and Future Challenges with Application Benchmarks on past, Present and Future Tri-Lab Computing Systems

    Science.gov (United States)

    Rajan, Mahesh; Doerfler, Douglas

    2010-09-01

    In this paper HPC architectural characteristics and their impact on application performance and scaling are investigated. Performance data gathered over several generations of very large HPC systems like: ASC Red Storm, ASC Purple, and a large InfiniBand cluster—Red Sky, are analyzed. As the number of cache coherent cores and number of NUMA domains at a compute node keeps increasing, we analyze their impact with a few simple benchmarks and several applications. We present bottlenecks and remedies examining production applications. We conclude with preliminary early-hardware performance data from the ASC Cielo, a petaFLOPS class future capability system.

  15. Application de la spectroscopie de fluorescence a l'étude du pétrole : le défi de la complexité Application of Fluorescence Spectroscopy to the Study of Petroleum: Challenging Complexity

    OpenAIRE

    Ellingsen G.; Fery-Forgues S.

    2006-01-01

    Grâce à sa sensibilité et à sa sélectivité, la spectroscopie de fluorescence est de plus en plus employée dans l'étude du pétrole. Dans un premier temps, les principes fondamentaux de cette technique sont rappelés, en mettant l'accent sur les difficultés inhérentes à la complexité du milieu et sur les développements récents comme la spectroscopie de fluorescence par excitation synchrone et la détection à distance. Par la suite, les principaux domaines d'application de la fluorescence à la tec...

  16. Application of the chemical properties of ruthenium to decontamination processes; L'application des proprietes chimiques du ruthenium a des procedes de decontamination

    Energy Technology Data Exchange (ETDEWEB)

    Fontaine, A.; Berger, D. [Commissariat a l' Energie Atomique, Centre de Production de Plutonium, Marcoule (France). Centre d' Etudes Nucleaires

    1965-07-01

    The chemical properties of ruthenium in the form of an aqueous solution of the nitrate and of organic tributylphosphate solution are reviewed. From this data, some known examples are given: they demonstrate the processes of separation or of elimination of ruthenium from radioactive waste. (authors) [French] Les proprietes chimiques du ruthenium en solutions aqueuses nitriques et en solutions organiques de tributylphosphate, sont passees en revue. A partir de ces donnees, quelques exemples connus sont cites: ils exposent des procedes de separation ou d'elimination du ruthenium de dechets radioactifs. (auteurs)

  17. Overview of linac applications at future radioactive beam facilities

    International Nuclear Information System (INIS)

    Nolen, Jerry A.

    1996-01-01

    There is considerable interest worldwide in the research which could be done at a next generation, advanced radioactive beam facility. To generate high quality, intense beams of accelerated radionuclides via the 'isotope separator on-line' (ISOL) method requires two major accelerator components: a high power (100 kW) driver device to produce radionuclides in a production target/ion source complex, and a secondary beam accelerator to produce beams of radioactive ions up to energies on the order of 10 MeV per nucleon over a broad mass range. In reviewing the technological challenges of such a facility, several types of modern linear accelerators appear well suited. This paper reviews the properties of the linacs currently under construction and those proposed for future facilities for use either as the driver device or the radioactive beam postaccelerator. Other choices of accelerators, such as cyclotrons, for either the driver or secondary beam devices of a radioactive beam complex will also be compared. Issues to be addressed for the production accelerator include the choice of ion beam types to be used for cost-effective production of radionuclides. For the post-accelerator the choice of ion source technology is critical and dictates the charge-to-mass requirements at the injection stage. (author)

  18. Overview of linac applications at future radioactive beam facilities

    International Nuclear Information System (INIS)

    Nolen, J.A.

    1996-01-01

    There is considerable interest worldwide in the research which could be done at a next generation, advanced radioactive beam facility. To generate high quality, intense beams of accelerated radionuclides via the open-quotes isotope separator on-lineclose quotes (ISOL) method requires two major accelerator components: a high power (100 kW) driver device to produce radionuclides in a production target/ion source complex, and a secondary beam accelerator to produce beams of radioactive ions up to energies on the order of 10 MeV per nucleon over a broad mass range. In reviewing the technological challenges of such a facility, several types of modem linear accelerators appear well suited. This paper reviews the properties of the linacs currently under construction and those proposed for future facilities for use either as the driver device or the radioactive beam post-accelerator. Other choices of accelerators, such as cyclotrons, for either the driver or secondary beam devices of a radioactive beam complex will also be compared. Issues to be addressed for the production accelerator include the choice of ion beam types to be used for cost-effective production of radionuclides. For the post-accelerator the choice of ion source technology is critical and dictates the charge-to-mass requirements at the injection stage

  19. Feasibility study of an image slicer for future space application

    Science.gov (United States)

    Calcines, A.; Ichimoto, K.

    2014-08-01

    This communication presents the feasibility study of an image slicer for future space missions, especially for the integral field unit (IFU) of the SUVIT (Solar UV-Visible-IR telescope) spectro-polarimeter on board the Japanese-led solar space mission Solar-C as a backup option. The MuSICa (Multi-Slit Image slicer based on collimator-Camera) image slicer concept, originally developed for the European Solar Telescope, has been adapted to the SUVIT requirements. The IFU will reorganizes a 2-D field of view of 10 x 10 arcsec2 into three slits of 0.18 arcsec width by 185.12 arcsec length using flat slicer mirrors of 100 μm width. The layout of MuSICa for Solar-C is telecentric and offers an optical quality limited by diffraction. The entrance for the SUVIT spectro-polarimeter is composed by the three IFU slits and one ordinal long slit to study, using high resolution spectro-polarimetry, the solar atmosphere (Photosphere and Chromosphere) within a spectral range between 520 nm (optionally 280 nm) and 1,100 nm.

  20. Current and future applications of high nitrogen steels

    International Nuclear Information System (INIS)

    Stein, G.; Hucklenbroich, I.; Feichtinger, H.

    1999-01-01

    For any new development there are just two gateways into the market: either it does relevant things never done before - in this case the market is ready to pay a considerable price. Or it does the usual things, but at a very competitive price. And of course, there is any combination of these two prerequisites. With nitrogen steels both concepts apply. On one hand there is the idea of substitution, i.e. replacing the expensive nickel by nitrogen. On the other hand there is a production of steels with an unprecedented combination of usually conflicting properties such as superior strength, toughness and corrosion resistance, as represented by the austenitic Cr-Mn-steel P900, which is used for retaining rings. In a way, success of a material and its usages, which become feasible, can be explained by looking at two things: property potential of a new material and process technology for the production of such material. HNS steels are already indispensable in some fields and we can be sure that they will grow to further importance in the near future. This contribution just makes a little round trip through the field of HNS leads from the technology of large scale generators to the world of fashion, from high tech building and wear resistant aircraft bearings and finally even to the world of medicine. (orig.)

  1. The application demand analysis of advanced photoelectric technology in the future unmanned vehicle loads

    Science.gov (United States)

    Zhang, Lei; Cao, Wei; Li, Shengcai; Lu, Peng

    2018-01-01

    Introduced some unmanned vehicles development present situation, points out that the main development trend of photoelectric technology, analyzes the basic ability requirement of unmanned vehicles, in the future war system demonstrates the photoelectric information transmission, battlefield situational awareness, photoelectric integrated optoelectronic technology such as against the application of the unmanned vehicles demand in the future.

  2. Stem cells in orthopedics: current concepts and possible future applications.

    Science.gov (United States)

    Bagaria, Vaibhav; Patil, Nilesh; Sapre, Vikram; Chadda, Anshul; Singrakia, Manoj

    2006-04-01

    Stem cells are the cells that have the ability to divide for indefinite periods in culture and to give rise to specialized cells. Sources of these cells include embryo, umbilical cord and certain sites in adults such as the central nervous system [CNS] and bone marrow. Its use hold promise of wide spread applications particularly in areas of spinal cord injury, difficult non-unions, critical bone defects, spinal fusions, augmentation of ligament reconstructions, cartilage repair and degenerative disc disorders. This review article contains current information derived from Medline searches on the use in various orthopedic subspecialties. Some issues remain at the forefront of the controversy involving stem cell research - legislation, ethics and public opinion, cost and concentration methods. As is true with any new technology, the enthusiasm for this technology that has potential to influence virtually every orthopedic case management, must be balanced by subjecting it to stringent clinical and basic research investigations.

  3. Current and future industrial application of electron accelerators in Thailand

    Energy Technology Data Exchange (ETDEWEB)

    Siri-Upathum, Chyagrit [Chulalongkorn Univ., Faculty of Engineering, Bangkok (Thailand)

    2003-02-01

    Industrial applications of electron accelerators in Thailand, first introduced in 1997 for radiation sterilized products such as doctor gown, pampas, feminine napkin etc followed by installation of accelerators, one with energies at 20 MV and the other at 5 MV to produce new value added products like gem stones, topaz, tourmaline and zircon. The machines operate in pulse mode and is also used for irradiation services for food and sterilized products treatment. The need for low and medium energy accelerators in radiation technology is stressed. They are to be used for crosslinking of electrical wire and cable, heat shrinkable materials, low protein concentrated rubber latex, rubber wood furniture and parts, and silk protein degradation. The role of governmental organizations like Nuclear Research Institute (OAEP) and universities in stimulating the utilization of radiation processing in Thailand is strengthened. (S. Ohno)

  4. Mathematical modelling of anaerobic digestion processes: applications and future needs

    DEFF Research Database (Denmark)

    Batstone, Damien J.; Puyol, Daniel; Flores Alsina, Xavier

    2015-01-01

    of the role of the central carbon catabolic metabolism in anaerobic digestion, with an increased importance of phosphorous, sulfur, and metals as electron source and sink, and consideration of hydrogen and methane as potential electron sources. The paradigm of anaerobic digestion is challenged by anoxygenic...... phototrophism, where energy is relatively cheap, but electron transfer is expensive. These new processes are commonly not compatible with the existing structure of anaerobic digestion models. These core issues extend to application of anaerobic digestion in domestic plant-wide modelling, with the need......Anaerobic process modelling is a mature and well-established field, largely guided by a mechanistic model structure that is defined by our understanding of underlying processes. This led to publication of the IWA ADM1, and strong supporting, analytical, and extension research in the 15 years since...

  5. Current and future industrial application of electron accelerators in Thailand

    International Nuclear Information System (INIS)

    Siri-Upathum, Chyagrit

    2003-01-01

    Industrial applications of electron accelerators in Thailand, first introduced in 1997 for radiation sterilized products such as doctor gown, pampas, feminine napkin etc followed by installation of accelerators, one with energies at 20 MV and the other at 5 MV to produce new value added products like gem stones, topaz, tourmaline and zircon. The machines operate in pulse mode and is also used for irradiation services for food and sterilized products treatment. The need for low and medium energy accelerators in radiation technology is stressed. They are to be used for crosslinking of electrical wire and cable, heat shrinkable materials, low protein concentrated rubber latex, rubber wood furniture and parts, and silk protein degradation. The role of governmental organizations like Nuclear Research Institute (OAEP) and universities in stimulating the utilization of radiation processing in Thailand is strengthened. (S. Ohno)

  6. Contribution to the study of the geophysical behaviour of lead-210 by application of alpha spectrometry; Contribution a l'etude du comportement geophysique du plomb 210 par application de la spectrometrie alpha

    Energy Technology Data Exchange (ETDEWEB)

    Nezami, M. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1965-06-01

    A study of the changes in the lead-210 contents of rain-water and of water produced by melting polar ice has required the development of a method for dosing lead-210, an {alpha} emitter. This method is 40 times more sensitive than that which measures the lead-210 by bismuth-210, a ({beta} emitter. The first part of the report presents the study of a spectrometry using semiconductor detectors; a catalogue of a spectra shows the advantages of this method. In the second part will be found at first a new chemical separation method for polonium-210 and the results obtained with this method. The main results obtained on the geophysical behaviour of lead-210 are the following: - the monthly lead-210 and polonium-210 contents in rain water are approximately constant with time. - in the Gif-sur-Yvette region, the clean-up by 'dry fall-out' can attain 40 to 50 per cent of the total fall-out. - a study of Antarctic ice samples makes it possible to determine an annual accumulation rate equivalent to 13.8 cm of water and to show discrepancies in the periodic concentrations which correspond to the latest maxima of solar activity. - a balance is drawn up between the radon produced by the continents and the lead-210 fall-out. (author) [French] Une etude sur les variations de la teneur en plomb 210 des eaux de pluie et des eaux de fusion des glaces polaires a necessite la mise au point d'une methode de dosage du plomb 210 emetteur {alpha}. Cette methode permet d'obtenir une sensibilite quarante fois superieure a celle dosant le plomb 210 par le bismuth 210 emetteur {beta}. La premiere partie du travail presente l'etude de la spectrometrie {alpha} par detecteur a semiconducteurs, un catalogue de spectres {alpha} met en evidence les avantages de cette methode. Dans la deuxieme partie on trouvera en premier lieu une nouvelle methode chimique de separation du polonium 210 ainsi que les resultats obtenus grace a cette methode. Les principaux resultats sur le

  7. Préparation et carectérisation du vanadium supporté sur la bentonite activée par acide. Application à l'oxydation du cyclohexane et à l'épxydation de cyclohexene.

    OpenAIRE

    AMIRI, ABDELALI

    2014-01-01

    Pa ge 26 Notre étude avait pour but la préparation des catalyseurs à base de vanadium supporté sur Montmorillonite activé par acide. Ces matériaux sont caractérisés par UV-vis et IR, ils sont testés ensuite dans l’oxydation du cyclohexane et désoxydation du cyclo hexene.L’analyse par UV- vis à réflexion diffuse du catalyseur V/H-Mont montre un pic autour 320 nm attribué à l’espèce du vanadium tétraédrique.La caractérisation par IR montre la présence des ponts entre le support et le vana...

  8. Évaluation de l'application par l'Afrique du Sud d'une taxe d'accise ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les maladies non transmissibles, qui contribuent de façon marquée à la charge de morbidité de l'Afrique du Sud sont largement causées par l'obésité et les maladies associées. La prévalence de l'obésité a augmenté de 30 % pendant la dernière décennie, tandis que la consommation d'aliments à haute teneur en énergie ...

  9. Vacuum deposited polymer films: Past, present, and future applications

    Energy Technology Data Exchange (ETDEWEB)

    Affinito, J.; Martin, P.; Gross, M.; Bennett, W.

    1994-11-01

    Two extremely high rate processes have been developed for the vacuum deposition of polymer thin films. Dubbed the PML (for Polymer Multi-Layer) and LML (for Liquid Multi-Layer) processes, the PML technique was originally developed for the manufacture of polymer/aluminum surface mount capacitors while the LML method arose from a need to fabricate lithium polymer batteries. These processes have since been found to be compatible with most other vacuum deposition techniques in, integrated, in-line coating processes. Battelle has developed an extensive program, and a great deal of hardware, to pursue a wide variety of PML and LML applications which integrate these two process technologies with other, conventional, vacuum deposition methods. The historical development of the technologies is reviewed and the Battelle PML/LML facilities are described. Current Battelle work involving solar thermal control films, PML QWOTs, and polymer/metal high reflectors are also discussed. Battelle PML work that is just starting, involving non-linear optical materials/devices, lithium polymer battery fabrication, electrochromic devices, and polymer/oxide multilayers, is discussed as well.

  10. LIGHT - from laser ion acceleration to future applications

    Science.gov (United States)

    Roth, Markus; Light Collaboration

    2013-10-01

    Creation of high intensity multi-MeV ion bunches by high power lasers became a reliable tool during the last 15 years. The laser plasma source provides for TV/m accelerating field gradients and initially sub-ps bunch lengths. However, the large envelope divergence and the continuous exponential energy spectrum are substential drawbacks for many possible applications. To face this problem, the LIGHT collaboration was founded (Laser Ion Generation, Handling and Transport). The collaboration consists of several university groups and research centers, namely TU Darmstadt, JWGU Frankfurt, HI Jena, HZDR Dresden and GSI Darmstadt. The central goal is building a test beamline for merging laser ion acceleration with conventional accelerator infrastructure at the GSI facility. In the latest experiments, low divergent proton bunches with a central energy of up to 10 MeV and containing >109 particles could be provided at up to 2.2 m behind the plasma source, using a pulsed solenoid. In a next step, a radiofrequency cavity will be added to the beamline for phase rotation of these bunches, giving access to sub-ns bunch lengths and reaching highest intensities. An overview of the LIGHT objectives and the recent experimental results will be given. This work was supported by HIC4FAIR.

  11. The biotechnology of ethanol. Classical and future applications

    Energy Technology Data Exchange (ETDEWEB)

    Roehr, M. [ed.] [Technische Univ., Vienna (Austria). Inst. fuer Biochemische Technologie und Mikrobiologie; Kosaric, N. [Western Ontario Univ., London, ON (Canada). Dept. of Chemical and Biochemical Engineering; Vardar-Sukan, F [Ege Univ., Izmir (Turkey). Dept. of Chemical Engineering; Pieper, H.J.; Senn, T. [Hohenheim Univ., Stuttgart (Germany). Inst. fuer Lebensmitteltechnologie

    2001-07-01

    Focusing on the biotechnology of ethanol, this book highlights its industrial relevance as one of the most important products of primary metabolism. The text covers the most advanced developments among classical methods as well as more unconventional techniques, before going on to outline various aspects of new applications and the increasing importance of ethanol as a renewable resource. Topics covered in this unique volume include alternative raw materials, such as municipal waste and waste paper or particular crops, innovative methods of production using genetically engineered microorganisms, and the role of ethanol as both a source of energy and a valuable commodity. The book is an indispensable reference in that it combines biotechnological and economic aspects, while also providing an overview of the state of the art in the production and use of ethanol. Throughout, special emphasis has been placed on a balanced presentation between developments in Europe as well as in North and South America. With contributions of T. Senn and H.J. Pieper and of N. Kosaric and F. Vardar-Sukan. (orig.)

  12. Human dental pulp stem cells: Applications in future regenerative medicine.

    Science.gov (United States)

    Potdar, Pravin D; Jethmalani, Yogita D

    2015-06-26

    Stem cells are pluripotent cells, having a property of differentiating into various types of cells of human body. Several studies have developed mesenchymal stem cells (MSCs) from various human tissues, peripheral blood and body fluids. These cells are then characterized by cellular and molecular markers to understand their specific phenotypes. Dental pulp stem cells (DPSCs) are having a MSCs phenotype and they are differentiated into neuron, cardiomyocytes, chondrocytes, osteoblasts, liver cells and β cells of islet of pancreas. Thus, DPSCs have shown great potentiality to use in regenerative medicine for treatment of various human diseases including dental related problems. These cells can also be developed into induced pluripotent stem cells by incorporation of pluripotency markers and use for regenerative therapies of various diseases. The DPSCs are derived from various dental tissues such as human exfoliated deciduous teeth, apical papilla, periodontal ligament and dental follicle tissue. This review will overview the information about isolation, cellular and molecular characterization and differentiation of DPSCs into various types of human cells and thus these cells have important applications in regenerative therapies for various diseases. This review will be most useful for postgraduate dental students as well as scientists working in the field of oral pathology and oral medicine.

  13. Endophytic nitrogen fixation in sugarcane: Present knowledge and future applications

    International Nuclear Information System (INIS)

    Boddey, Robert M.; Urquiaga, Segundo; Alves, Bruno J.R.; Reis, Veronica

    2001-01-01

    In Brazil the long-term continuous cultivation of sugarcane with low N fertiliser inputs, without apparent depletion of soil-N reserves, led to the suggestion that N 2 -fixing bacteria associated with the plants may be the source of agronomically significant N inputs to this crop. From the 1950s to 1970s, considerable numbers of N 2 -fixing bacteria were found to be associated with the crop, but it was not until the late 1980s that evidence from N balance and 15 N dilution experiments showed that some Brazilian varieties of sugarcane were able to obtain significant contributions from this source. The results of these studies renewed the efforts to search for N 2 -fixing bacteria, but this time the emphasis was on those diazotrophs that infected the interior of the plants. Within a few years several species of such 'endophytic diazotrophs' were discovered including Gluconacetobacter diazotrophicus, Herbaspirillum seropedicae, H. rubrisubalbicans and Burkholderia sp. Work has continued on these endophytes within sugarcane plants, but to date little success has been attained in elucidating which endophyte is responsible for the observed BNF and in what site, or sites, within the cane plants the N 2 fixation mainly occurs. Until such important questions are answered further developments or extension of this novel N 2 -fixing system to other economically important non-legumes (e.g. cereals) will be seriously hindered. As far as application of present knowledge to maximise BNF with sugarcane is concerned, molybdenum is an essential micronutrient. An abundant water supply favours high BNF inputs, and the best medium term strategy to increase BNF would appear to be based on cultivar selection on irrigated N deficient soils fertilised with Mo. (author)

  14. L'hydrogène : maillon essentiel du raffinage de l'avenir Hydrogen: an Essential Link in Refining of the Future

    Directory of Open Access Journals (Sweden)

    Raimbault C.

    2006-11-01

    Full Text Available L'hydrogène est déjà largement utilisé dans le raffinage du pétrole brut. L'évolution de la demande et de l'approvisionnement moyen augmentent les besoins en hydrogène. Un déficit éventuel peut être comblé par la purification ou la récupération de l'hydrogène de divers effluents ou par des unités de production autonomes alimentées par des fractions difficilement valorisables sur le marché. Hydrogen is already widely used in crude-oil refining. The evolution of the demand and mean supply is increasing the needs for hydrogen. An eventual deficit could be overcome by the purification or recovery of hydrogen from various effluents or by independent production plants fed with fractions that are difficult to upgrade on the market.

  15. Two Oil Types on the North Slope of Alaska. Implications for Future Exploration Les deux types d'huile du versant septentrional de l'Alaska. Implications pour l'exploration future

    Directory of Open Access Journals (Sweden)

    Magoon L. B.

    2006-10-01

    Full Text Available Forty oil samples from across the North Slope of Alaska have been analyzed by the US Bureau of Mines and the Us Geological Survey. Results of these analyses suggest two separate genetic oil types. The first type, the Simpson-Umiat oil type, occurs in reservoir rocks of Cretaceous and Quaternary age and includes oils from seeps in the Skull Cliff, Cape Simpson, Manning Point, and Ungoon Point areas; the Wolf Creek test well 3, and the Umiat oil field. These are higher gravity, low-sulfur oils with no, or slight, odd-numbered n-alkane predominance and pristane to phytane ratios greater than 1. 5. The second type, the Barrow-Prudhoe oil type, occurs in reservoir rocks of Carboniferous to Cretataceous age and includes ails from South Barrow gas field, Prudhoe Bay oil field, and the Fish Creek test well 1. Physical properties of Barrow-Prudhoe oils are variable, but in general the oils are medium-gravity, high-sulfur oils with a slight even-numbered n-alkane predominance and pristane to phytane ratio of less thon 1. 5. The two types are believed to originated from different source rocks; the Barrow-Prudhoe type may have originated from a carbonate or other iron-deficient source rock, and the Simpson-Umiat type from asiliciclastic source rock. Occurrences of fine two oil types, when outlined on a map, indicate atleast two exploration fairways. The fairway for the Barrow-Prudhoe type is along the Barrow arch, and the fairway, for the Simpson-Umiat type is the area of the best reservoir development for the Nanushuk Group. Quarante échantillons d'huile prélevés à travers le versant septentrional de l'Alaska ont été analysés par l'US Bureau of Mines et l'US Geological Survey. Les résultats de ces analyses suggèrent deux types séparés d'huile. Le premier, le type d'huile Simpson-Umiat, se trouve dans des roches magasins du Crétacé au Quaternaire et comprend des huiles des suintements des régions de la falaise Skull, du cap Simpson, de Point

  16. Contributions and Future of Radioisotopes in Medical, Industrial and Space Applications

    Science.gov (United States)

    Tingey, G. L.; Dix, G. P.; Wahlquist, E. J.

    1990-11-01

    There are 333 isotopes that have a half-life between 1 day and 100,000 years that have a wide variety of applications including public health, medicine,industrial technology, food technology and packaging, agriculture, energy supply, and national security. This paper provides an overview of some of the most extensive applications of radioisotopes including some observations of future uses. Examples are discussed that indicate that the use of radioisotopes is almost unlimited and will continue to grow. There is a growing need for future applications development and production. 12 refs., 1 tab. (BM)

  17. Contributions and future of radioisotopes in medical, industrial, and space applications

    Science.gov (United States)

    Tingey, G. L.; Dix, G. P.; Wahlquist, E. J.

    1990-11-01

    There are 333 isotopes that have a half-life between 1 day and 100,000 years that have a wide variety of applications including public health, medicine, industrial technology, food technology and packaging, agriculture, energy supply, and national security. This paper provides an overview of some of the most extensive applications of radioisotopes including some observations of future uses. Examples are discussed that indicate that the use of radioisotopes is almost unlimited and will continue to grow. There is a growing need for future applications development and production.

  18. Contributions and future of radioisotopes in medical, industrial and space applications

    International Nuclear Information System (INIS)

    Tingey, G.L.; Dix, G.P.; Wahlquist, E.J.

    1990-11-01

    There are 333 isotopes that have a half-life between 1 day and 100,000 years that have a wide variety of applications including public health, medicine,industrial technology, food technology and packaging, agriculture, energy supply, and national security. This paper provides an overview of some of the most extensive applications of radioisotopes including some observations of future uses. Examples are discussed that indicate that the use of radioisotopes is almost unlimited and will continue to grow. There is a growing need for future applications development and production. 12 refs., 1 tab. (BM)

  19. L’apprentissage du bien-être animal chez de futures professionnels animaliers : des éthiques animals malmenées

    Directory of Open Access Journals (Sweden)

    Vidal Michel

    2015-01-01

    Full Text Available Les débats dont le bien-être animal est l’objet entre chercheurs, professionnels et associations en font une question socialement vive scientifico-éthique. Ils en interrogent l’éducabilité alors que cette notion est prise en compte dans les curricula de l’enseignement agricole. Envisageant son enseignement au travers d’une éducation à l’empathie interspécifique, nous questionnons les facteurs susceptibles de l’influencer. Nous nous fondons sur le discours de sept élèves en baccalauréat professionnel relevant de l’élevage d’animaux de production ou d’animaux de compagnie durant deux années de formation. Six élèves, quelle que soit leur filière de formation, souhaitent créer une relation affective sans nécessairement développer une attitude empathique durant la formation. Parmi les facteurs responsables, nous distinguons (1 un manque de confiance en soi de l’élève, (2 des motivations égocentrées primant sur des motivations zoocentrées, (3 la loyauté et les habitudes acquises à l’égard des pratiques parentales, (4 la conformation aux pratiques et idéologies dominantes du monde professionnel, (5 des facteurs associés aux situations d’enseignement (savoirs et pratiques de référence qui font autorité, valeurs de conformité primant sur des valeurs éthiques, dissociation de la dimension relationnelle et productive de l’élevage, jugements négatifs portés par l’enseignant et les élèves originaires du monde agricole. Ces facteurs généreraient des mécanismes de défense chez l’élève nuisibles au développement d’un raisonnement affectivo-éthique critique.

  20. Rapport du Département fédéral de l'intérieur concernant la structure actuelle et le développement futur de la conception helvétique des trois piliers de la prévoyance vieillesse, survivants et invalidité Aspects de la Sécurité Sociale

    CERN Document Server

    Suisse. Département fédéral de l'intérieur

    1995-01-01

    Rapport du Département fédéral de l'intérieur concernant la structure actuelle et le développement futur de la conception helvétique des trois piliers de la prévoyance vieillesse, survivants et invalidité

  1. L'éco-conception dans le génie électrique : application au cas du transformateur

    OpenAIRE

    Debusschere , Vincent; BEN AHMED , Hamid; Multon , Bernard

    2007-01-01

    National audience; Ce papier présente les premiers résultats de la problématique de l'éco-conception dans le cas du plus simple des convertisseurs électromagnétiques : le transformateur monophasé connecté à un réseau à tension et fréquence fixes. L'optimisation de ses dimensions s'obtient par la minimisation de deux objectifs contradictoires, la masse des parties actives et le coût énergétique global sur cycle de vie. Nous comparons dans un premier temps ces résultats d'optimisation à ceux d'...

  2. The future of breast cancer radiotherapy: From one size fits all to taylor-made treatment; L'avenir de la radiotherapie du cancer du sein: de la taille unique au sur-mesure

    Energy Technology Data Exchange (ETDEWEB)

    Hennequin, C. [Service de cancerologie-radiotherapie, hopital Saint-Louis, 1, avenue Claude-Vellefaux, 75475 Paris (France); Azria, D. [Departement de cancerologie radiotherapie, CRLC Val-d' Aurelle-Paul-Lamarque, rue Croix-Verte, 34298 Montpellier cedex 5 (France); Universite de Montpellier I, 5, boulevard Henri-IV, CS 19044, 34967 Montpellier cedex 2 (France); Inserm U896, institut de recherche en cancerologie de Montpellier, CRLC Val-d' Aurelle-Paul-Lamarque, rue Croix-Verte, 34298 Montpellier cedex 5 (France)

    2011-10-15

    Various subgroups of breast tumours have been identified during the last 10 years according to the risk of local relapse. Prognostic factors for local relapse are age, surgical margins, tumour size, Her2 expression and hormonal receptors status. For tumours with a high risk of local relapse, an increased in boost dose or the addition of new drugs (trastuzumab, anti-angiogenics, PARP inhibitors) could be considered. For low risk tumours, hypo-fractionated, accelerated partial breast and intraoperative radiotherapy are being evaluated. The classical schedule (45-50 Gy to the whole gland followed by a boost dose of 16 Gy) is no longer the universal rule. Treatment individualization, according to clinical and biological characteristics of the tumour and - possibly - to the radiobiological profile of the patient, is likely to be the future of breast cancer radiotherapy. (authors)

  3. Google Livres et le futur des bibliothèques numériques historique du projet, techniques documentaires, alternatives et controverses

    CERN Document Server

    Jacquesson, Alain

    2010-01-01

    En 2004, le monde du livre apprend le projet fou de deux jeunes illuminés : construire en cinq ans une bibliothèque numérique universelle. Six ans plus tard, une gigantesque bibliothèque numérique de plus de 12 millions de volumes a vu le jour. Des collections, que des générations de conservateurs ont mis des siècles à constituer, sont avalées par Google Livres. Jamais une collaboration d'une telle envergure entre les secteurs publics et privés n'avait été entreprise dans le domaine patrimonial. Dans le monde entier, les chercheurs comme le grand public s'habituent peu à peu à utiliser Google Livres, qui dit viser maintenant 30 millions de livres numériques. Cette réalisation a nécessité l'élaboration de compétences informatiques spécifiques, notamment en ce qui concerne la numérisation de masse. L'efficacité de ce savoir-faire a suscité l'intérêt de nombreuses bibliothèques qui ont choisi de participer au projet. Cette appropriation des biens publics soulève aussi de nombreuses c...

  4. Advanced remote handling for future applications: The advanced integrated maintenance system

    International Nuclear Information System (INIS)

    Herndon, J.N.; Kring, C.T.; Rowe, J.C.

    1986-01-01

    The Consolidated Fuel Reprocessing Program at Oak Ridge National Laboratory has been developing advanced techniques for remote maintenance of future US fuel reprocessing plants. The developed technology has a wide spectrum of application for other hazardous environments. These efforts are based on the application of teleoperated, force-reflecting servomanipulators for dexterous remote handling with television viewing for large-volume hazardous applications. These developments fully address the nonrepetitive nature of remote maintenance in the unstructured environments encountered in fuel reprocessing. This paper covers the primary emphasis in the present program; the design, fabrication, installation, and operation of a prototype remote handling system for reprocessing applications, the Advanced Integrated Maintenance System

  5. Application de la spectroscopie de fluorescence a l'étude du pétrole : le défi de la complexité Application of Fluorescence Spectroscopy to the Study of Petroleum: Challenging Complexity

    Directory of Open Access Journals (Sweden)

    Ellingsen G.

    2006-12-01

    Full Text Available Grâce à sa sensibilité et à sa sélectivité, la spectroscopie de fluorescence est de plus en plus employée dans l'étude du pétrole. Dans un premier temps, les principes fondamentaux de cette technique sont rappelés, en mettant l'accent sur les difficultés inhérentes à la complexité du milieu et sur les développements récents comme la spectroscopie de fluorescence par excitation synchrone et la détection à distance. Par la suite, les principaux domaines d'application de la fluorescence à la technologie du pétrole sont successivement passés en revue, en particulier la détection de la pollution, la caractérisation rapide des bruts, l'information pour l'exploration et le forage, et enfin l'analyse fine des constituants. Les réactifs fluorogéniques ne sont utilisés qu'après minéralisation de l'échantillon et essentiellement pour détecter les traces de métaux. Due to its sensitivity and selectivity, fluorescence spectroscopy is increasingly used in petroleum technology. Firstly, the fundamentals of fluorescence are briefly presented, emphasizing the many difficulties encountered because of the medium complexity and the recent developments of methods like synchronously excited fluorescence spectroscopy and remote detection. Then, the main application fields are successively reviewed, that is identification of pollutant sources, crude oils fingerprinting, information for drilling and exploration and finally the analysis of petroleum constituents. Fluorogenic reactants are only used for trace metal detection after sample mineralization.

  6. Cri du chat syndrome

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/001593.htm Cri du chat syndrome To use the sharing features on this page, please enable JavaScript. Cri du chat syndrome is a group of symptoms that result ...

  7. formes histologiques particulieres du cancer du nasopharynx

    African Journals Online (AJOL)

    19 déc. 2007 ... tique. Nous avons étudié le profil thérapeutique et évolutif de ces formes rares. J. TUN ORL - N° 19 DÉCEMBRE 2007. 47. FORMES HISTOLOGIQUES PARTICULIERES. DU CANCER DU NASOPHARYNX. H. DHOUIB, M. MNEJJA, W. BOUAYED, A.CHAKROUN, T. BOUDAWARA*,. I. CHARFEDDINE, M.

  8. Bulletin du CRDI #123

    International Development Research Centre (IDRC) Digital Library (Canada)

    Dans ce numéro, découvrez comment les travaux de recherche que nous finançons contribuent à l'autonomisation des femmes. Apprenez-en plus sur notre nouveau partenariat avec Cancer Research UK, et n'oubliez pas de participer à notre Assemblée publique annuelle. Logo du Bulletin du CRDI Bulletin du CRDI ...

  9. Present status and future trends of industrial radioisotopes application in Sudan

    International Nuclear Information System (INIS)

    Salih, A.S.

    2008-06-01

    Radioisotopes continue to play an important role in better management of natural resources, industrial growth and environmental preservation. The success of radioisotope applications is due primarily to the ability, conferred by the unique properties of radioactive materials, to collect data, where conventional methods fail or become uneconomical. These are prompt, on-line, in-situ and do not disturb the main industrial process in any way. In Sudan, the application of these nuclear techniques has considerable economic and environmental impact. This paper casts light on the present application of radioisotopes and future trends in the country.(Author)

  10. Elsevier's Article of the Future enhancing the user experience and integrating data through applications

    Directory of Open Access Journals (Sweden)

    IJsbrand Jan Aalbersberg

    2012-03-01

    Full Text Available In a world where our levels of knowledge advance rapidly, so should the communication of research. In partnership with the world's research community, Elsevier investigates the future of research communication with the ‘Article of the Future’. An intuitive online article format, this proposes the next generation in research publishing, with a simple-to-read online layout and enriched content, allowing true immersion in the subject matter. In addition, through the use of SciVerse® Applications, the Article of the Future connects the formal scientific record with associated external data sets and other contextual information that is available elsewhere on the web. In this article, we present the outcomes of the second phase of the Article of the Future project, with an emphasis on its final designs, user feedback collected, and how the Article of the Future handles the rising need of connecting the formal scientific record with associated discipline-specific data sets.

  11. La gouvernance du CRDI

    International Development Research Centre (IDRC) Digital Library (Canada)

    d'assurer l'intégrité des systèmes d'information de gestion et de contrôle interne;. · de suivre de près le rendement du Centre en fonction du cadre stratégique et des plans .... Adjointe spéciale principale auprès du président du Nigeria chargée des objectifs du Millénaire pour le développement. A assisté à 1 réunion sur 3.

  12. Contributions and future of radioisotopes in medical industrial, and space applications

    International Nuclear Information System (INIS)

    Tingey, G.L.; Wahlquist, E.J.

    1991-01-01

    Of the over 2300 isotopes identified to data, more than 1700 are short-lived with half-lives less than one day, 283 are stable, and 333 have a half-life between 1 day and 100,000 years. It is on this last group that the authors focus for the isotopes with useable radioactivity. Radioisotopes are used in a wide variety of applications including public health, medicine, industrial technology, food technology and packaging, agriculture, energy supply, and national security. The purpose of this paper is to provide an overview of some of the most extensive applications of radioisotopes including some observations of future uses. As for the future, we expect radioisotopes to contribute to a myriad of diverse applications to improve technological, scientific, and industrial endeavors, which include improving the length and quality of life through improved diagnosis and treatment of the human ills

  13. Richard Lavenham on Future Contingents

    DEFF Research Database (Denmark)

    Øhrstrøm, Peter

    1983-01-01

    ‘Richard Lavenham on Future Contingents’, Cahiers de l’Institut du Moyen-âge Grec et Latin, 44 (1983), p.180-186.......‘Richard Lavenham on Future Contingents’, Cahiers de l’Institut du Moyen-âge Grec et Latin, 44 (1983), p.180-186....

  14. Micro-reactor for heterogeneous catalysis. Application: hydrogen production from methyl-cyclohexane; Microreacteur pour la catalyse heterogene. Application: production d'hydrogene a partir du methylcyclohexane

    Energy Technology Data Exchange (ETDEWEB)

    Roumanie, M.; Pijolat, C. [Ecole des Mines de Saint Etienne, Centre SPIN (DMICC/LPMG/URA/CNRS-D2021), 42 - Saint Etienne (France); Meille, V.; Bellefon, C. de [Centre National de la Recherche Scientifique (CNRS/CPE), Lab. de Genie des Procedes Catalytiques, 69 - Villeurbanne (France); Pouteau, P.; Delattre, C. [CEA Grenoble, Lab. d' Electronique et de Technologie de l' Informatique (LETI), 38 (France)

    2004-07-01

    First developed by the pharmaceutical industry to find new drugs (combinatorial analysis), the lab on chip is also extremely interesting for the catalysis field. This major interest comes from the miniaturize size and the high surface on volume ratio which lead to improve mass and heat transfer but also the safety in regards of industrial application. The use of micro-technology and the miniaturization of various systems such as micro-fuel cell is also a current field of activity. So for the future research the production of hydrogen is a point to develop in order to supply a micro-fuel cell. The aim of this work is to study and to realize an autonomous catalytic micro-reactor for hydrogen production from methyl-cyclohexane. For this reaction of dehydrogenation, the common catalyst is platinum supported on alumina. Consequently, the general objectives of this work are: 1)to develop a micro-reactor with its heaters, sensors...2)to deposit catalysts in the micro-reactor 3)to study the catalytic conversion of this system.

  15. Nanocellulose as a sustainable biomass material: structure, properties, present status and future prospects in biomedical applications.

    Science.gov (United States)

    Xue, Yan; Mou, Zihao; Xiao, Huining

    2017-10-12

    Nanocellulose, extracted from the most abundant biomass material cellulose, has proved to be an environmentally friendly material with excellent mechanical performance owing to its unique nano-scaled structure, and has been used in a variety of applications as engineering and functional materials. The great biocompatibility and biodegradability, in particular, render nanocellulose promising in biomedical applications. In this review, the structure, treatment technology and properties of three different nanocellulose categories, i.e., nanofibrillated cellulose (NFC), nanocrystalline cellulose (NCC) and bacterial nanocellulose (BNC), are introduced and compared. The cytotoxicity, biocompatibility and frontier applications in biomedicine of the three nanocellulose categories were the focus and are detailed in each section. Future prospects concerning the cytotoxicity, applications and industrial production of nanocellulose are also discussed in the last section.

  16. The refining industry and the future of the fuel oils; L'industrie du raffinage et le devenir des fiouls lourds

    Energy Technology Data Exchange (ETDEWEB)

    Soleille, S

    2004-01-15

    The fuel oils consumption decrease in France since 1970, because of the two petroleum crisis, the nuclear energy competition and the air pollution. The fuel oils industry is then looking other export possibilities. This report aims to offer a first approach of the problem and presents the main challenges. The first part is devoted to the technical context (definition, production and outlet. The second part presents the environmental context and the fuel oils market. In the third part the market is studied at the world scale, in the fourth at the french scale and in the fifth at the scale of other countries as United States, Japan and european Union. A synthesis tables is given in the last part to compare and propose some hypothesis concerning the future of fuel oils and the french refining industry. (A.L.B.)

  17. Social Gaming and Learning Applications: A Driving Force for the Future of Virtual and Augmented Reality?

    Science.gov (United States)

    Dörner, Ralf; Lok, Benjamin; Broll, Wolfgang

    Backed by a large consumer market, entertainment and education applications have spurred developments in the fields of real-time rendering and interactive computer graphics. Relying on Computer Graphics methodologies, Virtual Reality and Augmented Reality benefited indirectly from this; however, there is no large scale demand for VR and AR in gaming and learning. What are the shortcomings of current VR/AR technology that prevent a widespread use in these application areas? What advances in VR/AR will be necessary? And what might future “VR-enhanced” gaming and learning look like? Which role can and will Virtual Humans play? Concerning these questions, this article analyzes the current situation and provides an outlook on future developments. The focus is on social gaming and learning.

  18. Application of adaptive antenna techniques to future commercial satellite communications. Executive summary

    Science.gov (United States)

    Ersoy, L.; Lee, E. A.; Matthews, E. W.

    1987-01-01

    The purpose of this contract was to identify the application of adaptive antenna technique in future operational commercial satellite communication systems and to quantify potential benefits. The contract consisted of two major subtasks. Task 1, Assessment of Future Commercial Satellite System Requirements, was generally referred to as the Adaptive section. Task 2 dealt with Pointing Error Compensation Study for a Multiple Scanning/Fixed Spot Beam Reflector Antenna System and was referred to as the reconfigurable system. Each of these tasks was further subdivided into smaller subtasks. It should also be noted that the reconfigurable system is usually defined as an open-loop system while the adaptive system is a closed-loop system. The differences between the open- and closed-loop systems were defined. Both the adaptive and reconfigurable systems were explained and the potential applications of such systems were presented in the context of commercial communication satellite systems.

  19. Fiche technique du spermogramme et du spermocytogramme ...

    African Journals Online (AJOL)

    En Afrique la stérilité du couple constitue un drame social. Selon l'OMS, environ 8 à 12 % des couples africains sont touchés par une infertilité. La responsabilité masculine dans la stérilité est comprise entre 30 à 40%. Les causes de l'infertilité masculine peuvent être l'impuissance et/ ou l'altération du sperme. L'étude de ...

  20. HTML5 May Provide Vital Link for Friendly Future Mobile Applications

    Science.gov (United States)

    2012-01-01

    31Army Communicator HTML5 may provide vital link for friendly future mobile applications By LTC Gregory Motes An important thread that has exist...would be accomplished with the maturation of HTML5 . To fully grasp the opportunity, one needs to be aware of the history of Hy- perText Markup...number of devices in both on-line and off-line states. To many, this would be accomplished with the maturation of HTML5 . (Continued on page 32

  1. The single photon diagnosis and the therapy applications in nuclear oncology: past, present and future

    International Nuclear Information System (INIS)

    Giammarile, F.

    2005-01-01

    The principal applications of the nuclear medicine concern the diagnosis. It can be added the information in the evaluation of the therapy response and in the evaluation of a future risk. The potential of development in nuclear medicine is in new radiopharmaceuticals, especially new pathophysiologic information can be gotten every time a new molecule is discovered and one of the principal aims of diagnostic imaging is the in vivo tissue characterization. (N.C.)

  2. Effets diffractifs et fonction de transfert de l'atmosphère à grande distance: Application au 'rumble' du bang sonique

    OpenAIRE

    Delorme, Philippe

    2010-01-01

    National audience; La propagation dans l'atmosphère du bang sonique est un phénomène complexe. Du point de vue des résultats expérimentaux fondés sur le bang sonique du Concorde, on peut distinguer quatre zones: champ proche (quelques longueurs du mobile), champ moyen (trace au sol dans la carpette primaire, fin des effets non-linéaires), champ lointain ( entre 50 et 500 kilomètres ), champ très lointain ( au delà de 500 kilomètres). La première zone se modélise avec les équations de la mécan...

  3. Dans la future société du coût marginal zéro, les imprimantes 3D rendront-elles serviles ?

    OpenAIRE

    Becar, Jean-Paul; Vareille, Jean

    2017-01-01

    International audience; 1 LAMAV, CNRS 2956, IUT Valenciennes, UVHC-Campus Mont Houy-59313 VALENCIENNES 2 Lab-STICC UMR 6285-Université de Brest, IUT de Brest-Morlaix, département GMP, CS 93837 29238 BREST CEDEX 3 THEMATIQUE – Energie-Environnement CNU 27 et CNU 60 RESUME-L'impression 3D constitue un sujet phare de ces dernières années. L'industrie, l'éducation et les particuliers sont tous concernés par cette nouvelle technologie. Les applications sont à la fois prometteuses et ambitieuses, n...

  4. Envisioning the Future of Aquatic Animal Tracking: Technology, Science, and Application

    Energy Technology Data Exchange (ETDEWEB)

    Lennox, Robert J.; Aarestrup, Kim; Cooke, Steven J.; Cowley, Paul D.; Deng, Zhiqun D.; Fisk, Aaron T.; Harcourt, Robert G.; Heupel, Michelle; Hinch, Scott G.; Holland, Kim N.; Hussey, Nigel E.; Iverson, Sara J.; Kessel, Steven T.; Kocik, John F.; Lucas, Martyn C.; Flemming, Joanna Mills; Nguyen, Vivian M.; Stokesbury, Michael J. W.; Vagle, Svein; VanderZwaag, David L.; Whoriskey, Frederick G.; Young, Nathan

    2017-09-13

    Electronic tags have proven to be extremely useful for broadening our understanding of aquatic animals by answering diverse questions about their behaviours, physiologies, and life histories fundamental to ecology. Simultaneously, many applied conservation and management efforts are informed by animals tagged with electronic tags. In spite of the many advances in tracking software and hardware, an uncertain future in the world’s aquatic ecosystems portends great challenges for science. Aquatic animal tracking with electronic tags represents both the present and future of integrative biology and ecology in aquatic ecosystems. Here we identify what we regard as the future of aquatic animal tracking in a horizon scanning exercise. We submit that the future of aquatic animal tracking will include opportunities for multi-platform tracking systems for simultaneously monitoring position, activity, physiology, and microhabitat of animals, improved data collection and accessibility with new infrastructure (e.g. tags, receivers) and cyberinfrastructure, and integrated tagging information with animal traits derived from biopsy during tagging. We discuss parallel needs and opportunities in areas related to the application of animal tracking in the future such as knowledge mobilization and governance.

  5. Une méthode pour estimer l’interception du rayonnement par un couvert bas : application au colza avant montaison

    Directory of Open Access Journals (Sweden)

    Denoroy Pascal

    2002-01-01

    Full Text Available Dans les modèles de simulation du fonctionnement des cultures, l’interception du rayonnement est une variable cruciale pour la prévision de la productivité en biomasse. D’autre part, la connaissance de l’interception du rayonnement par une culture permet de mieux analyser la réponse à un traitement en autorisant la distinction entre les effets morphogénétique et physiologique du traitement. Par exemple, dans l’étude de la fertilisation azotée du colza [1] on a pu faire la part de l’effet morphogénétique (accroissement de l’indice foliaire, donc de l’interception et de l’amélioration de la conversion photosynthétique du rayonnement absorbé. Dans un cas comme dans l’autre, une estimation correcte de l’interception du rayonnement est essentielle. Très souvent, un formalisme dérivé de la loi de Beer-Lambert est utilisé pour quantifier la part interceptée du rayonnement : PARi = epsiloni PAR (1 et epsiloni = 1 - e- k.IF (2, PAR représentant le rayonnement photosynthétiquement actif incident (exprimé en Joules ou en moles de photons, PARi la part de ce dernier interceptée par le couvert, epsiloni le coefficient (sans dimension d’interception, IF l’indice foliaire et k le coefficient d’extinction du rayonnement. Un formalisme un peu plus complexe doit être utilisé si on veut considérer le rayonnement absorbé [1, 2]. Pour des cultures couvrantes, la sensibilité de ces modèles à la valeur de k est faible pour les IF élevés, c’est pourquoi ces modèles sont souvent utilisés avec succès. Mais aux faibles IF, les modèles sont sensibles à k, d’où l’importance de l’estimation de ce paramètre pour les cultures présentant une longue période de faible couverture du sol, tel le colza peu fertilisé en phase hivernale. De plus, pour les cultures discontinues, c’est-à-dire présentant des zones où le sol n’est pas du tout couvert par la végétation, comme les inter-rangs, on doit

  6. Les Cahiers du CREAD

    African Journals Online (AJOL)

    Admin

    cette économie. Cette technique d'estimation permet de connaître la taille relative de l'économie informelle et d'en suivre l'évolution au cours du temps. ..... Mémoire de Magister en Sciences économiques, Université de Tlemcen. Bounoua C, (1992). Une lecture critique du secteur informel dans les pays du tiers monde, ...

  7. Bulletin du CRDI #124

    International Development Research Centre (IDRC) Digital Library (Canada)

    Les femmes jouent un rôle important dans les exploitations minières artisanales et à petite échelle en Afrique subsaharienne. De concert ... Couverture du livre: Une vie saine pour les femmes et les enfants vulnérables · Couverture du livre: Entre el activismo y la intervención · Couverture du livre: Revitalizing Health for All.

  8. Panorama et futur de la filière du soja français

    Directory of Open Access Journals (Sweden)

    Labalette Françoise

    2010-11-01

    Full Text Available Soybean is cultivated in Europe as a GM free cultivation. In spite of a growing demand in identity preserved (IP seeds and of the high environmental benefit of the soybean in the crop rotations,a great decrease of the soybean acreage has been observed in France and in Europe since 2002. That’s why in 2007, Cetiom and Onidol, two bodies of the French oilseed crop organisation decided to carry out a comprehensive survey on the different actors of the soybean production chain from the farmers until the feed and food soybean users. The study showed that 12% of the total acreage is planted under organic farming and that most surfaces are still grown under IP process. It also highlighted that the decrease of soybean’s surfaces till 2008 was mainly due to an insufficient economic competitiveness compared to other crops. The survey proved that the French production gained market shares between 2002 and 2007 for the soyfood industry supply (from 5 to 25% of the total acreage. The remaining production is processed in small or medium extrusion plants for the local animal raising. The needs of the industry were described in details showing that the main asset of the French production is the good control of the whole production chain, the high quality management by the farmers, the good protein content and shorter logistic chains compared to the imported soybean. For the future, the increasing environmental constraints and the larger demand of European soyfood industry but also of local high-quality feed and animal raising could lead soybean to recover between 100 000 and 150 000 hectares in France.

  9. Introduction du principe du pollueur-payeur au sein des services publics de la commune de Randogne

    OpenAIRE

    Renna, Giovanna; Barbey, Valérie

    2014-01-01

    Ce travail a pour objectif d’aider la commune de Randogne à approfondir le sujet des taxes, respectant le principe du pollueur-payeur, applicables aux domaines du traitement des déchets, de la distribution d’eau potable et du traitement des eaux usées. De plus, il expose différents systèmes de taxation possibles afin de lui permettre de choisir celui qui est le mieux adapté à ses besoins.

  10. Superconducting Radio-Frequency Technology R&D for Future Accelerator Applications

    Science.gov (United States)

    Reece, Charles E.; Ciovati, Gianluigi

    2012-01-01

    Superconducting rf (SRF) technology is evolving rapidly, as are its applications. While there is active exploitation of what one may call the current state-of-the-practice, there is also rapid progress in expanding in several dimensions the accessible and useful parameter space. While state-of-the-art performance sometimes outpaces thorough understanding, the improving scientific understanding from active SRF research is clarifying routes to obtain optimum performance from present materials and opening avenues beyond the standard bulk niobium. The improving technical basis understanding is enabling process engineering to improve both performance confidence and reliability and also unit implementation costs. Increasing confidence in the technology enables the engineering of new creative application designs. We attempt to survey this landscape to highlight the potential for future accelerator applications.

  11. Recent Advances and Future Challenges for Artificial Neural Systems in Geotechnical Engineering Applications

    Directory of Open Access Journals (Sweden)

    Mohamed A. Shahin

    2009-01-01

    Full Text Available Artificial neural networks (ANNs are a form of artificial intelligence that has proved to provide a high level of competency in solving many complex engineering problems that are beyond the computational capability of classical mathematics and traditional procedures. In particular, ANNs have been applied successfully to almost all aspects of geotechnical engineering problems. Despite the increasing number and diversity of ANN applications in geotechnical engineering, the contents of reported applications indicate that the progress in ANN development and procedures is marginal and not moving forward since the mid-1990s. This paper presents a brief overview of ANN applications in geotechnical engineering, briefly provides an overview of the operation of ANN modeling, investigates the current research directions of ANNs in geotechnical engineering, and discusses some ANN modeling issues that need further attention in the future, including model robustness; transparency and knowledge extraction; extrapolation; uncertainty.

  12. ÉTUDE DU TRAITEMENT DES SILOXANES PAR ADSORPTION SUR MATÉRIAUX POREUX : APPLICATION AU TRAITEMENT DES BIOGAZ

    OpenAIRE

    Ricaurte Ortega, Deyanira

    2009-01-01

    Study of a treatment of siloxane by adsorption process into porous materials: treatment application to biogas Biogases have strong content of methane used in the production of heat or electricity. They contain more or less important quantities of siloxanes, which are forbidden for numerous uses of biogases. The possibility of siloxanes elimination by adsorption process is studied. The study in batch reactors allows us to evaluate the adsorption capacities of different materials as activated c...

  13. Effect of Experience of Internal Medicine Residents during Infectious Disease Elective on Future Infectious Disease Fellowship Application

    Science.gov (United States)

    2017-10-04

    Experience of !ntcrnal Medicine Residents during Infectious Disease Elective on Future lntCctious Di~casc Fcllo\\vship Application Sb. GRANT N_UMBER...Internal Medidne Residents during Infectious Disease Elective on Future Infectious Disease Fello\\\\/shlp Application Blyth Dl’vl, Barsournian 1\\E, Yun I-IC...Medicine Residents during Infectious Disease Elective on Fut ure Infectious Disease Fellowship Application ~ Poeter# 1440 .,...._,: OVfil"S~ ti

  14. Jeux vidéo éducatifs et motivation: application à l'enseignement du jazz

    OpenAIRE

    Denis , Guillaume

    2006-01-01

    This Ph.D. thesis introduces what we believe to be the first musical educational video game: Pads'n'Swing. Indeed, even though video game have been raising concerns for years, their integration in the very fabric of society and the ever increasing breadth of their use pave the way to positive applications such as serious games, which rely on players' interaction and social networking and the design and simulation of virtual worlds. Building upon this approach, we suggest to put fun at the for...

  15. Automatic-Control Challenges in Future Urban Vehicles: A Blend of Chassis, Energy and Networking Management Les défis de la commande automatique dans les futurs véhicules urbains : un mélange de gestion de châssis, d’énergie et du réseau

    Directory of Open Access Journals (Sweden)

    Savaresi S.M.

    2012-10-01

    Full Text Available The topic of this paper is the discussion of new challenges that the scientific field of automatic-control will face in the next decades, in the area of vehicles control. The focus is on urban vehicles for personal mobility, since this type of vehicles will be subject to the biggest changes in the next decades. The paper is articulated in three sections – in a top-down framework – briefly addressing and discussing the following items: the main drivers, which will force a change in urban personal mobility; the main types of vehicles, which are expected to address at best such drivers; the main automatic-control challenges on such type of vehicles. The scope of this paper is purposely non-technical. Its aim is mainly to discuss the emerging new challenges from the perspective of the automatic-control scientists and practitioners. The goal of the paper is to establish a discussion framework on the problems and opportunities, which will arise in this field, in the near future. Le sujet du présent article est une discussion sur les nouveaux défis auxquels le domaine scientifique de la commande automatique des véhicules va faire face dans les prochaines décennies. L’accent est mis sur les véhicules urbains destinés à une mobilité individuelle, puisque c’est ce type de véhicules qui va faire l’objet des plus grands changements dans les prochaines décennies. Le présent article s’articule, selon une démarche descendante, en trois sections abordant et discutant brièvement les éléments suivants : les principaux moteurs qui vont imposer un changement en matière de mobilité individuelle; les principaux types de véhicules qui sont attendus pour répondre au mieux à de tels moteurs et les principaux défis de la commande automatique sur un tel type de véhicules. À dessein, la portée du présent article est non technique. Son but est principalement de discuter les nouveaux défis émergeants, à partir de perspectives des

  16. Simulation du mouvement humain en vue d'applications ergonomiques - Vers une approche de simulation basée sur données et assistée par connaissances

    OpenAIRE

    WANG, X

    2003-01-01

    Le mannequin numérique, comme outil de conception, a pour objectif de permettre aux ingénieurs de prendre en compte des facteurs humains dans la conception de produits ou de postes de travail. Il doit être capable de représenter le futur opérateur ou l'utilisateur du produit, de simuler son activité, d'évaluer ses interactions avec son environnement et d'en déduire des informations sur les astreintes subies. Si les avancées technologiques, notamment dans le domaine informatique, permettent un...

  17. [Therapeutic applications and promises of cellular and tissue engineering. What strategic choice for the Etablissement Français du Sang?].

    Science.gov (United States)

    Hervé, Patrick

    2007-05-01

    A new medical field, known as regeneration medicine, is developing and attracting more and more researchers and practitioners. Whereas hematopoietic cell-based therapies have already proven their efficacy in numerous--malignant or not--diseases, non-hematopoietic cell-based therapies have not. They can be useful to dozens, if not hundreds, of patients with various disorders, such as cardiopathy, diabetes, some types of cancer, osteoarticular and neurodegenerative disorders. In these fields, numerous clinical applications are possible for mesenchymal stem cells. Cell and tissue (corneas, bone, skin) therapy products require the definition of pharmaceutical standards with new European requirements in terms of quality and safety. The legitimacy of the Etablissement Français du Sang (EFS) in cell and tissue engineering activities is established, it is recognized by most specialists and by regulatory authorities and has been asserted by the orientations of its "contrat d'objectifs et de moyens". An independent committee has been set up by the EFS President to define an EFS-specific strategy. This committee made up of qualified specialists was required to draw up a rational organization plan for these activities, in order for EFS to be in a position to produce cells and tissues according to pharmaceutical standards. The committee proposals are based on economic data and an inventory of existing cell and tissue engineering activities. Public/private partnerships are required and efforts must focus towards the industrial valorization of EFS expertise in R&D activities and staff know-how. Implementing such a new organization requires national management and the cooperation of institutional actors (university hospitals, cancer treatment centers, universities). For the success of this approach, EFS personnel must be convinced of its legitimacy and new skills must be encouraged. With its numerous assets, EFS can be ambitious and assert itself as a major actor in cell and

  18. The automobile of the future: engine technologies and automotive fuels developed by IFP; l'automobile du futur: les technologies moteurs et carburants developpes par l'IFP

    Energy Technology Data Exchange (ETDEWEB)

    Appert, O.; Pinchon, Ph.

    2004-07-01

    In front of the challenges of climate change and depletion of petroleum reserves, in front of the continuous strengthening of pollution regulations applied to automobile (Euro IV and V) and the advances of R and D, several ways of research can be explored to answer the mobility needs of the coming decades. The IFP takes stock of these topics in this press kit which comprises 11 documents: the synthesis of O. Appert and P. Pinchon's talk about 'the cleaner and multi-energies automobile of the future', the slides of this presentation, the future evolutions of automobiles motorizations, the long-term evolutions of engines/fuels (brief for the Panorama 2004 colloquium), diesel fuel in the USA (brief for the Panorama 2004 colloquium), bio-fuels in Europe (brief for the Panorama 2004 colloquium), diesel pollution abatement: efficient results from the IFP's diesel combustion process 'NADI'(TM), the presentation of the IFP scientific meeting of September 22-23, 2004 'which fuels for low CO{sub 2} engines?', the strategic positioning of IFP in the world energy and environmental context, the brochures 'IFP engines and fuels: a competitive advantage' and 'innovating for a sustainable development in the domain of energy'. (J.S.)

  19. PCMs for Residential Building Applications: A Short Review Focused on Disadvantages and Proposals for Future Development

    Directory of Open Access Journals (Sweden)

    Ashley Bland

    2017-08-01

    Full Text Available Phase change materials (PCMs offer great potential as a latent heat energy storage technique to provide energy efficient systems in new and existing residential buildings. Due to their unique characteristic of high storage densities and latent heat properties, PCMs provide opportunities for greater energy storage in many applications for residential buildings. These applications include, but are not limited to, solar water heating, space heating/cooling, and waste heat recovery. This study reviews PCM systems in residential building applications, with a focus on their major disadvantages and concludes with proposals for future development. Several disadvantages of PCM use in the given application have been identified and include; super cooling, low thermal conductivity, phase segregation, fire safety, and cost. The issues caused by super cooling and phase segregation lead to thermal cycling degradation, limiting the useful lifecycle of the material. These issues could limit their potential in building applications, which require systems of a long lifespan. Low thermal conductivities can slow down the rate at which heat is distributed or absorbed from the building, which affect the occupants comfort and as well as the efficiency of the system. Ideas based on the current research on ways to limit these disadvantages are included in the study. This study also identifies that further research is required on novel maintenance ways for the PCM systems after they have been installed.

  20. Developments of large-area APD arrays for future applications to PET technology

    International Nuclear Information System (INIS)

    Kataoka, Jun

    2010-01-01

    Silicon avalanche photodiodes (APD) are solid-state devices which have internal gain. Since the good features of both photodiodes (PDs) and photomultiplier tubes (PMTs) are shared in a single device, APD offers new design for physics experiments and devices for nuclear medicine. In particular, thanks to its high quantum efficiency (QE) and low noise, reverse-type APDs generally show much better energy resolution than traditional PMTs when coupled to various scintillators. Most recently, we have developed various large area reverse-type APDs with Hamamatsu Photonics, up to 32 x 32 mm 2 square area. Such large dimensions have been awaited by researchers world-wide, and further extend the potential of APDs for various application such as in space science and nuclear medicine. For example, the use of APDs in space experiments is now validated thanks to successful launch of the Cute 1.7+APD II, which has measured both electron/proton distributions in Low Earth Orbit at E >9 keV. Moreover, the mission successfully demonstrated an active gain control system to keep the APD gain stable under moderate temperature variations. In other aspects, an APD is a compact, high performance light sensor that could be used in the strong magnetic field MRIs. An ultimate spatial resolution as better as sub-mm will be possible by adopting small pixel, high density APD pixels. Future PET detectors with time-of-flight (TOF) capability may be expected thanks to very fast time response of the APD devices. As a first step, we have developed a versatile APD-based positron emission tomography (PET) modules for future applications in high resolution, fast medical imaging. We will also discuss future use of digital (Geiger-mode) APDs, such as multi-pixel photon counter (MPPCs) in similar medical imaging applications. (author)

  1. Environmental application research and future plans in plasma arc technology at the georgia institute of technology

    International Nuclear Information System (INIS)

    Nemeth, J.

    1996-01-01

    This paper summarizes the facilities and past, current, and future research efforts at the georgia institute of technology plasma Arc research facility established in 1992. This research facility was established specifically to develop and test applications related to waste management and various remediation concepts. The results of research programs in the vitrification of asbestos materials, municipal incinerator ash, and in situ testing programs, including soil remediation, waste to energy research, landfill remediation and capacity management. The presentation will also include conference and symposium announcements and invitations. 9 tabs

  2. A Compact Design of Planar Array Antenna with Fractal Elements for Future Generation Applications

    DEFF Research Database (Denmark)

    Ojaroudiparchin, Naser; Shen, Ming; Pedersen, Gert F.

    2016-01-01

    In this paper, a planar phased array fractal antenna for the future fifth generation (5G) applications is presented. The proposed array antenna is designed to operate at 22 GHz. 64 patch antenna elements with coaxial-probe feeds have been used for the proposed design. The antenna elements are based...... on Vicsek fractal geometry where the third iteration patches operate over a wide bandwidth and contribute to improve the efficiency and realized gain performance. The designed planar array has more than 22 dB realized gain and -0.3 dB total efficiency when its beam is tilted to 0 degrees elevation...

  3. Emulation of long-term changes in global climate: application to the late Pliocene and future

    KAUST Repository

    Lord, Natalie S.

    2017-11-16

    Multi-millennial transient simulations of climate changes have a range of important applications, such as for investigating key geologic events and transitions for which high-resolution palaeoenvironmental proxy data are available, or for projecting the long-term impacts of future climate evolution on the performance of geological repositories for the disposal of radioactive wastes. However, due to the high computational requirements of current fully coupled general circulation models (GCMs), long-term simulations can generally only be performed with less complex models and/or at lower spatial resolution. In this study, we present novel long-term

  4. Emulation of long-term changes in global climate: Application to the late Pliocene and future

    KAUST Repository

    Lord, Natalie S.

    2017-04-26

    Multi-millennial transient simulations of climate changes have a range of important applications, such as for investigating key geologic events and transitions for which high-resolution palaeoenvironmental proxy data are available, or for projecting the long-term impacts of future climate evolution on the performance of geological repositories for the disposal of radioactive wastes. However, due to the high computational requirements of current fully coupled general circulation models (GCMs), long-term simulations can generally only be performed with less complex models and/or at lower spatial resolution. In this study, we present novel long-term

  5. Shaping laser accelerated ions for future applications – The LIGHT collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Busold, S., E-mail: s.busold@gsi.de [Institut für Kernphysik, Technische Universität Darmstadt, Schloßgartenstraße 9, D-64289 Darmstadt (Germany); Almomani, A. [Institut für angewandte Physik, Johann-Wolfgang-Goethe-Universität Frankfurt, Max von Laue Straße 1, D-60438 Frankfurt (Germany); Bagnoud, V. [GSI Helmholtzzentrum für Schwerionenforschung, Planckstraße 1, D-64291 Darmstadt (Germany); Helmholtz Institut Jena, Fröbelstieg 3, D-07734 Jena (Germany); Barth, W. [GSI Helmholtzzentrum für Schwerionenforschung, Planckstraße 1, D-64291 Darmstadt (Germany); Bedacht, S. [Institut für Kernphysik, Technische Universität Darmstadt, Schloßgartenstraße 9, D-64289 Darmstadt (Germany); Blažević, A. [GSI Helmholtzzentrum für Schwerionenforschung, Planckstraße 1, D-64291 Darmstadt (Germany); Helmholtz Institut Jena, Fröbelstieg 3, D-07734 Jena (Germany); Boine-Frankenheim, O. [GSI Helmholtzzentrum für Schwerionenforschung, Planckstraße 1, D-64291 Darmstadt (Germany); Institut für Theorie Elektromagnetischer Felder, Technische Universität Darmstadt, Schloßgartenstraße 8, D-64289 Darmstadt (Germany); and others

    2014-03-11

    The generation of intense ion beams from high-intensity laser-generated plasmas has been the focus of research for the last decade. In the LIGHT collaboration the expertise of heavy ion accelerator scientists and laser and plasma physicists has been combined to investigate the prospect of merging these ion beams with conventional accelerator technology and exploring the possibilities of future applications. We report about the goals and first results of the LIGHT collaboration to generate, handle and transport laser driven ion beams. This effort constitutes an important step in research for next generation accelerator technologies.

  6. modelisation du comportement hydrologique du bassin versant

    African Journals Online (AJOL)

    LGE

    paramètres sont vérifiés sur la (s) période (s) de contrôle afin de s‟assurer que la modélisation n‟était pas ... critère est très utilisé en hydrologie pour évaluer les performances des modèles pluie-débit. .... Cela exprime la bonne performance et la meilleure applicabilité du modèle CEQUEAU au bassin versant du. Boubo.

  7. DuSK: A Dual Structure-preserving Kernel for Supervised Tensor Learning with Applications to Neuroimages

    Science.gov (United States)

    He, Lifang; Kong, Xiangnan; Yu, Philip S.; Ragin, Ann B.; Hao, Zhifeng; Yang, Xiaowei

    2015-01-01

    With advances in data collection technologies, tensor data is assuming increasing prominence in many applications and the problem of supervised tensor learning has emerged as a topic of critical significance in the data mining and machine learning community. Conventional methods for supervised tensor learning mainly focus on learning kernels by flattening the tensor into vectors or matrices, however structural information within the tensors will be lost. In this paper, we introduce a new scheme to design structure-preserving kernels for supervised tensor learning. Specifically, we demonstrate how to leverage the naturally available structure within the tensorial representation to encode prior knowledge in the kernel. We proposed a tensor kernel that can preserve tensor structures based upon dual-tensorial mapping. The dual-tensorial mapping function can map each tensor instance in the input space to another tensor in the feature space while preserving the tensorial structure. Theoretically, our approach is an extension of the conventional kernels in the vector space to tensor space. We applied our novel kernel in conjunction with SVM to real-world tensor classification problems including brain fMRI classification for three different diseases (i.e., Alzheimer's disease, ADHD and brain damage by HIV). Extensive empirical studies demonstrate that our proposed approach can effectively boost tensor classification performances, particularly with small sample sizes. PMID:25927014

  8. DuSK: A Dual Structure-preserving Kernel for Supervised Tensor Learning with Applications to Neuroimages.

    Science.gov (United States)

    He, Lifang; Kong, Xiangnan; Yu, Philip S; Ragin, Ann B; Hao, Zhifeng; Yang, Xiaowei

    With advances in data collection technologies, tensor data is assuming increasing prominence in many applications and the problem of supervised tensor learning has emerged as a topic of critical significance in the data mining and machine learning community. Conventional methods for supervised tensor learning mainly focus on learning kernels by flattening the tensor into vectors or matrices, however structural information within the tensors will be lost. In this paper, we introduce a new scheme to design structure-preserving kernels for supervised tensor learning. Specifically, we demonstrate how to leverage the naturally available structure within the tensorial representation to encode prior knowledge in the kernel. We proposed a tensor kernel that can preserve tensor structures based upon dual-tensorial mapping. The dual-tensorial mapping function can map each tensor instance in the input space to another tensor in the feature space while preserving the tensorial structure. Theoretically, our approach is an extension of the conventional kernels in the vector space to tensor space. We applied our novel kernel in conjunction with SVM to real-world tensor classification problems including brain fMRI classification for three different diseases ( i.e ., Alzheimer's disease, ADHD and brain damage by HIV). Extensive empirical studies demonstrate that our proposed approach can effectively boost tensor classification performances, particularly with small sample sizes.

  9. A Bright Future for Precision Medicine: Advances in Fluorescent Chemical Probe Design and Their Clinical Application.

    Science.gov (United States)

    Garland, Megan; Yim, Joshua J; Bogyo, Matthew

    2016-01-21

    The Precision Medicine Initiative aims to use advances in basic and clinical research to develop therapeutics that selectively target and kill cancer cells. Under the same doctrine of precision medicine, there is an equally important need to visualize these diseased cells to enable diagnosis, facilitate surgical resection, and monitor therapeutic response. Therefore, there is a great opportunity for chemists to develop chemically tractable probes that can image cancer in vivo. This review focuses on recent advances in the development of optical probes, as well as their current and future applications in the clinical management of cancer. The progress in probe development described here suggests that optical imaging is an important and rapidly developing field of study that encourages continued collaboration among chemists, biologists, and clinicians to further refine these tools for interventional surgical imaging, as well as for diagnostic and therapeutic applications. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Inclusion and Functionalization of Polymers with Cyclodextrins: Current Applications and Future Prospects

    Directory of Open Access Journals (Sweden)

    Christian Folch-Cano

    2014-09-01

    Full Text Available The numerous hydroxyl groups available in cyclodextrins are active sites that can form different types of linkages. They can be crosslinked with one another, or they can be derivatized to produce monomers that can form linear or branched networks. Moreover, they can form inclusion complexes with polymers and different substrates, modifying their physicochemical properties. This review shows the different applications using polymers with cyclodextrins, either by forming inclusion complexes, ternary complexes, networks, or molecularly imprinted polymers (MIPs. On one hand, the use of cyclodextrins enhances the properties of each polymer, and on the other the use of polymers decreases the amount of cyclodextrins required in different formulations. Both cyclodextrins and polymers contribute synergistically in several applications such as pharmacological, nutritional, environmental, and other industrial fields. The use of polymers based on cyclodextrins is a low cost easy to use potential tool with great future prospects.

  11. Advanced power converters for universal and flexible power management in future electricity network - Converter applications in future European electricity network

    DEFF Research Database (Denmark)

    Iov, Florin; Blaabjerg, Frede

    The present report summarizes the work done in the Work Package 2 where the main goal is to provide essential data for the other workpackages in the UNIFLEX-PM project and determines in detail the performance requirements that will be placed upon power converters to make the Future European...

  12. An assessment of advanced displays and controls technology applicable to future space transportation systems

    Science.gov (United States)

    Hatfield, Jack J.; Villarreal, Diana

    1990-01-01

    The topic of advanced display and control technology is addressed along with the major objectives of this technology, the current state of the art, major accomplishments, research programs and facilities, future trends, technology issues, space transportation systems applications and projected technology readiness for those applications. The holes that may exist between the technology needs of the transportation systems versus the research that is currently under way are addressed, and cultural changes that might facilitate the incorporation of these advanced technologies into future space transportation systems are recommended. Some of the objectives are to reduce life cycle costs, improve reliability and fault tolerance, use of standards for the incorporation of advancing technology, and reduction of weight, volume and power. Pilot workload can be reduced and the pilot's situational awareness can be improved, which would result in improved flight safety and operating efficiency. This could be accomplished through the use of integrated, electronic pictorial displays, consolidated controls, artificial intelligence, and human centered automation tools. The Orbiter Glass Cockpit Display is an example examined.

  13. Rapport annuel 2012 Chapitre VI des Statut et Règlement du Personnel

    CERN Document Server

    Schepens, A

    2013-01-01

    Le rapport annuel 2012 concernant l’application du Chapitre VI (Règlement des différends et discipline) des Statut et Règlement du personnel a pour objet de rendre compte des demandes de réexamen, des recours internes, des recours auprès du Tribunal administratif de l’Organisation internationale du travail (TAOIT) et des cas où une sanction disciplinaire a été prise.

  14. Rapport annuel 2011 Chapitre VI des Statut et Règlement du Personnel

    CERN Document Server

    Schepens, A

    2012-01-01

    Le rapport annuel 2012 concernant l’application du Chapitre VI (Règlement des différends et discipline) des Statut et Règlement du personnel a pour objet de rendre compte des demandes de réexamen, des recours internes, des recours auprès du Tribunal administratif de l’Organisation internationale du travail (TAOIT) et des cas où une sanction disciplinaire a été prise.

  15. Evaluation of the applicability in the future climate of a statistical downscaling method in France

    Science.gov (United States)

    Dayon, G.; Boé, J.; Martin, E.

    2013-12-01

    compared to the magnitude of observed trends. Moreover some spurious trends in downscaled precipitation associated with temporal inconsistencies in reanalyses variables as surface humidity are noted. It is therefore difficult to assess the applicability of the downscaling methods in the future climate and their respective skill based on trends. Because of those difficulties, a perfect model approach is developed. In the surrogate world of a regional climate model (RCM), the statistical downscaling relation is established in its present climate and then applied to downscale its future projection. It is finally possible to compare future climate change simulated by the RCM and the result of the SD to test the stationarity hypothesis. To obtain robust results, the perfect model framework is applied to 12 RCMs from the ENSEMBLES project. Several analogs methods using different combination of predictors are tested. Some methods, very skillful for present-day interannual variability, are unable to reproduce correctly changes simulated by the RCMs. Another method with similar skill in the present climate, which only differs by the inclusion of the specific humidity at 850 hPa as predictor, is generally applicable in the future climate.

  16. A peek into the future of radiology using big data applications.

    Science.gov (United States)

    Kharat, Amit T; Singhal, Shubham

    2017-01-01

    Big data is extremely large amount of data which is available in the radiology department. Big data is identified by four Vs - Volume, Velocity, Variety, and Veracity. By applying different algorithmic tools and converting raw data to transformed data in such large datasets, there is a possibility of understanding and using radiology data for gaining new knowledge and insights. Big data analytics consists of 6Cs - Connection, Cloud, Cyber, Content, Community, and Customization. The global technological prowess and per-capita capacity to save digital information has roughly doubled every 40 months since the 1980's. By using big data, the planning and implementation of radiological procedures in radiology departments can be given a great boost. Potential applications of big data in the future are scheduling of scans, creating patient-specific personalized scanning protocols, radiologist decision support, emergency reporting, virtual quality assurance for the radiologist, etc. Targeted use of big data applications can be done for images by supporting the analytic process. Screening software tools designed on big data can be used to highlight a region of interest, such as subtle changes in parenchymal density, solitary pulmonary nodule, or focal hepatic lesions, by plotting its multidimensional anatomy. Following this, we can run more complex applications such as three-dimensional multi planar reconstructions (MPR), volumetric rendering (VR), and curved planar reconstruction, which consume higher system resources on targeted data subsets rather than querying the complete cross-sectional imaging dataset. This pre-emptive selection of dataset can substantially reduce the system requirements such as system memory, server load and provide prompt results. However, a word of caution, "big data should not become "dump data" due to inadequate and poor analysis and non-structured improperly stored data. In the near future, big data can ring in the era of personalized and

  17. A peek into the future of radiology using big data applications

    Directory of Open Access Journals (Sweden)

    Amit T Kharat

    2017-01-01

    Full Text Available Big data is extremely large amount of data which is available in the radiology department. Big data is identified by four Vs – Volume, Velocity, Variety, and Veracity. By applying different algorithmic tools and converting raw data to transformed data in such large datasets, there is a possibility of understanding and using radiology data for gaining new knowledge and insights. Big data analytics consists of 6Cs – Connection, Cloud, Cyber, Content, Community, and Customization. The global technological prowess and per-capita capacity to save digital information has roughly doubled every 40 months since the 1980's. By using big data, the planning and implementation of radiological procedures in radiology departments can be given a great boost. Potential applications of big data in the future are scheduling of scans, creating patient-specific personalized scanning protocols, radiologist decision support, emergency reporting, virtual quality assurance for the radiologist, etc. Targeted use of big data applications can be done for images by supporting the analytic process. Screening software tools designed on big data can be used to highlight a region of interest, such as subtle changes in parenchymal density, solitary pulmonary nodule, or focal hepatic lesions, by plotting its multidimensional anatomy. Following this, we can run more complex applications such as three-dimensional multi planar reconstructions (MPR, volumetric rendering (VR, and curved planar reconstruction, which consume higher system resources on targeted data subsets rather than querying the complete cross-sectional imaging dataset. This pre-emptive selection of dataset can substantially reduce the system requirements such as system memory, server load and provide prompt results. However, a word of caution, “big data should not become “dump data” due to inadequate and poor analysis and non-structured improperly stored data. In the near future, big data can ring in the

  18. A peek into the future of radiology using big data applications

    Science.gov (United States)

    Kharat, Amit T.; Singhal, Shubham

    2017-01-01

    Big data is extremely large amount of data which is available in the radiology department. Big data is identified by four Vs – Volume, Velocity, Variety, and Veracity. By applying different algorithmic tools and converting raw data to transformed data in such large datasets, there is a possibility of understanding and using radiology data for gaining new knowledge and insights. Big data analytics consists of 6Cs – Connection, Cloud, Cyber, Content, Community, and Customization. The global technological prowess and per-capita capacity to save digital information has roughly doubled every 40 months since the 1980's. By using big data, the planning and implementation of radiological procedures in radiology departments can be given a great boost. Potential applications of big data in the future are scheduling of scans, creating patient-specific personalized scanning protocols, radiologist decision support, emergency reporting, virtual quality assurance for the radiologist, etc. Targeted use of big data applications can be done for images by supporting the analytic process. Screening software tools designed on big data can be used to highlight a region of interest, such as subtle changes in parenchymal density, solitary pulmonary nodule, or focal hepatic lesions, by plotting its multidimensional anatomy. Following this, we can run more complex applications such as three-dimensional multi planar reconstructions (MPR), volumetric rendering (VR), and curved planar reconstruction, which consume higher system resources on targeted data subsets rather than querying the complete cross-sectional imaging dataset. This pre-emptive selection of dataset can substantially reduce the system requirements such as system memory, server load and provide prompt results. However, a word of caution, “big data should not become “dump data” due to inadequate and poor analysis and non-structured improperly stored data. In the near future, big data can ring in the era of personalized

  19. UV-curable hybrid polymers for optical applications: technical challenges, industrial solutions, and future developments

    Science.gov (United States)

    Gruetzner, G.; Klein, J.; Vogler, M.; Schleunitz, A.

    2014-03-01

    Advanced micro- and nanofabrication processes are constantly evolving from academic R&D environment towards real production technology. Therefore, the availability of suitable polymers for optical applications plays a crucial role to satisfy not only application based requirements but also the compatibility to industrial production technologies. In this context, UV-curable hybrid polymers, i.e. inorganic-organic materials obtained by sol-gel chemistry, were recently implemented into mass production environment, e.g. for micro-lenses in mobile device applications. In this contribution, we report on the development of innovative hybrid polymers and their tailoring towards an easy and fast processing with reliable and reproducible performance output for industrial large-scale production. Based on a discussion on standard process parameters with respect to optimize the material's performance, the technical demands of industrial manufacture to the hybrid polymers will be subsequently reviewed by giving selective examples. This will be complemented by a brief description of current R&D activities adapting hybrid polymers to future patterning technologies.

  20. Human iPSC for Therapeutic Approaches to the Nervous System: Present and Future Applications

    Directory of Open Access Journals (Sweden)

    Maria Giuseppina Cefalo

    2016-01-01

    Full Text Available Many central nervous system (CNS diseases including stroke, spinal cord injury (SCI, and brain tumors are a significant cause of worldwide morbidity/mortality and yet do not have satisfying treatments. Cell-based therapy to restore lost function or to carry new therapeutic genes is a promising new therapeutic approach, particularly after human iPSCs became available. However, efficient generation of footprint-free and xeno-free human iPSC is a prerequisite for their clinical use. In this paper, we will first summarize the current methodology to obtain footprint- and xeno-free human iPSC. We will then review the current iPSC applications in therapeutic approaches for CNS regeneration and their use as vectors to carry proapoptotic genes for brain tumors and review their applications for modelling of neurological diseases and formulating new therapeutic approaches. Available results will be summarized and compared. Finally, we will discuss current limitations precluding iPSC from being used on large scale for clinical applications and provide an overview of future areas of improvement. In conclusion, significant progress has occurred in deriving iPSC suitable for clinical use in the field of neurological diseases. Current efforts to overcome technical challenges, including reducing labour and cost, will hopefully expedite the integration of this technology in the clinical setting.

  1. Étude anatomique d'une espèce de lémurien (Eulemur fulvus) : coupes topographiques et tomodensitométriques du thorax, de l'abdomen et du bassin. Application à la pratique de l'échographie du cœur et des reins

    OpenAIRE

    Raharison, Fidiniaina

    2008-01-01

    L'objectif de notre étude est d'élaborer un document de référence mettant en relation l'anatomie, l'imagerie et la clinique du lémurien brun (Eulemur fulvus) et débouchant sur des mesures échographiques normales des reins et du cœur. Les études anatomique et tomodensitométrique ont été effectuées sur deux lémuriens et l'étude échographique sous différents modes sur 16 animaux après anesthésie. Les coupes anatomiques et tomodensitométriques nous ont permis de préciser la position et la conform...

  2. Piquet Caroline, Histoire du canal de Suez, Paris, Perrin, 2009, 372 p.

    Directory of Open Access Journals (Sweden)

    Claudine Piaton

    2011-01-01

    Full Text Available Les études sur l'histoire du canal de Suez connaissent un regain d'intérêt chez les historiens français. Nathalie Montel avait ouvert la voie en 1998 en publiant un ouvrage passionnant sur le percement du canal, Le chantier du canal de Suez, 1859-1869. Une histoire des pratiques techniques. L'étude s'arrêtait à l'ouverture du canal en 1869, laissant le champ libre à de futurs travaux. La publication en 2008 de l'ouvrage de Caroline Piquet, La Compagnie du canal de Suez, une concession françai...

  3. Rupture traumatique du diaphragme

    OpenAIRE

    Nordback, P.L.G.

    2006-01-01

    Résumé Rupture traumatique du diaphragme La rupture traumatique du diaphragme a été décrite la première fois par Sennertus en 1541. Ambroise Paré, en 1579, décrivit le premier cas de rupture traumatique du diaphragme diagnostiqué à l'autopsie. Une rupture traumatique du diaphragme existe chez 3 à 5% des patients polytraumatisés. En général la réparation chirurgicale est simple. La mortalité globale atteint 20 à 25%, elle est en général liée aux lésions associées, à la sévérité de la ...

  4. Du Pont de Nemours

    NARCIS (Netherlands)

    Ros JPM; LAE

    1994-01-01

    Dit rapport over Du Pont de Nemours (produktie van o.a. chemische stoffen) is gepubliceerd binnen het Samenwerkingsproject Procesbeschrijvingen Industrie Nederland (SPIN). In het kader van dit project is informatie verzameld over industriele bedrijven of industriele processen ter ondersteuning

  5. Structured Multi-level Data Fusion and Modelling of Heterogeneous Environmental Data for Future Internet Applications

    Science.gov (United States)

    Sabeur, Zoheir; Chakravarthy, Ajay; Bashevoy, Maxim; Modafferi, Stefano

    2013-04-01

    important approach provides a strong basis for the delivery of environmental observations at desired spatial and temporal scales to multiple users with various needs of spatial and temporal resolutions. It has also led to building robust future internet specific enablers on data fusion, which can indeed be used for multiple usage areas above and beyond the environmental domains of the Future Internet. In this paper, data and processing workflow scenarios shall be described. The fucntionalities of the multi-level fusion services shall be demonstrated and made accessible to the wider communities of the Fututre Internet. [1] The Environmental Observation Web and its Service Applications within the Future Internet. ENVIROFI IP. FP7-2011-ICT-IF Pr.No: 284898 http://www.envirofi.eu/

  6. Bulletin du CRDI #122

    International Development Research Centre (IDRC) Digital Library (Canada)

    24 sept. 2017 ... Des Népalaises utilisent un égrenoir à maïs manuel pour retirer les grains de maïs des épis · Une simple trousse d'agriculture vient faciliter la vie des paysans cultivant les terrasses au Népal La vie des paysans cultivant les terrasses du centre du Népal n'est pas facile. L'introduction de nouvelles pratiques ...

  7. Estimation of Cyclic Interstory Drift Capacity of Steel Framed Structures and Future Applications for Seismic Design

    Directory of Open Access Journals (Sweden)

    Edén Bojórquez

    2014-01-01

    Full Text Available Several studies have been devoted to calibrate damage indices for steel and reinforced concrete members with the purpose of overcoming some of the shortcomings of the parameters currently used during seismic design. Nevertheless, there is a challenge to study and calibrate the use of such indices for the practical structural evaluation of complex structures. In this paper, an energy-based damage model for multidegree-of-freedom (MDOF steel framed structures that accounts explicitly for the effects of cumulative plastic deformation demands is used to estimate the cyclic drift capacity of steel structures. To achieve this, seismic hazard curves are used to discuss the limitations of the maximum interstory drift demand as a performance parameter to achieve adequate damage control. Then the concept of cyclic drift capacity, which incorporates information of the influence of cumulative plastic deformation demands, is introduced as an alternative for future applications of seismic design of structures subjected to long duration ground motions.

  8. Effects of cosmetic formulations containing hydroxyacids on sun-exposed skin: current applications and future developments.

    Science.gov (United States)

    Kornhauser, Andrija; Coelho, Sergio G; Hearing, Vincent J

    2012-01-01

    This paper describes recent data on the effects of various skin formulations containing hydroxyacids (HAs) and related products on sun-exposed skin. The most frequently used classes of these products, such as α- and β-hydroxyacids, polyhydroxy acids, and bionic acids, are reviewed, and their application in cosmetic formulations is described. Special emphasis is devoted to the safety evaluation of these formulations, particularly on the effects of their prolonged use on sun-exposed skin. We also discuss the important contribution of cosmetic vehicles in these types of studies. Data on the effects of HAs on melanogenesis and tanning are also included. Up-to-date methods and techniques used in those explorations, as well as selected future developments in the cosmetic area, are presented.

  9. Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association.

    Science.gov (United States)

    Fox, Caroline S; Hall, Jennifer L; Arnett, Donna K; Ashley, Euan A; Delles, Christian; Engler, Mary B; Freeman, Mason W; Johnson, Julie A; Lanfear, David E; Liggett, Stephen B; Lusis, Aldons J; Loscalzo, Joseph; MacRae, Calum A; Musunuru, Kiran; Newby, L Kristin; O'Donnell, Christopher J; Rich, Stephen S; Terzic, Andre

    2015-05-12

    The field of genetics and genomics has advanced considerably with the achievement of recent milestones encompassing the identification of many loci for cardiovascular disease and variable drug responses. Despite this achievement, a gap exists in the understanding and advancement to meaningful translation that directly affects disease prevention and clinical care. The purpose of this scientific statement is to address the gap between genetic discoveries and their practical application to cardiovascular clinical care. In brief, this scientific statement assesses the current timeline for effective translation of basic discoveries to clinical advances, highlighting past successes. Current discoveries in the area of genetics and genomics are covered next, followed by future expectations, tools, and competencies for achieving the goal of improving clinical care. © 2015 American Heart Association, Inc.

  10. Application of hot melt extrusion for poorly water-soluble drugs: limitations, advances and future prospects.

    Science.gov (United States)

    Lu, Ming; Guo, Zhefei; Li, Yongcheng; Pang, Huishi; Lin, Ling; Liu, Xu; Pan, Xin; Wu, Chuanbin

    2014-01-01

    Hot melt extrusion (HME) is a powerful technology to enhance the solubility and bioavailability of poorly water-soluble drugs by producing amorphous solid dispersions. Although the number of articles and patents about HME increased dramatically in the past twenty years, there are very few commercial products by far. The three main obstacles limiting the commercial application of HME are summarized as thermal degradation of heat-sensitive drugs at high process temperature, recrystallization of amorphous drugs during storage and dissolving process, and difficulty to obtain products with reproducible physicochemical properties. Many efforts have been taken in recent years to understand the basic mechanism underlying these obstacles and then to overcome them. This article reviewed and summarized the limitations, recent advances, and future prospects of HME.

  11. Orbit Correction Methods - Basic Formulation, Current Applications at Jefferson Lab, and Future Possibilities

    International Nuclear Information System (INIS)

    A. Orbit Correction System Optimization: Recipes for optimizing an orbit correction system configuration at the design level are presented. Linear algebraic tools are applied to various flavors of response matrices to uniformly control unobservability, uncorrectability, and response matrix singularity. Application at Jefferson Lab is discussed. B. Orbit Correction at Jefferson Lab: Unique challenges posed by orbit correction, as well as algorithms and tools developed at the CEBAF accelerator at Jefferson Lab are discussed. C. Orbit Interpretation and Virtual Monitors: A new approach to developing an orbit correction package with software structural, algorithmic and operational advantages is introduced. It consists of an orbit interpretation module, a virtual monitor module, and a generic steering engine. Mathematical formulation, algorithms prototyped and tested on simulated and real data, and future possibilities are discussed

  12. Application of an estimation model to predict future transients at US nuclear power plants

    International Nuclear Information System (INIS)

    Hallbert, B.P.; Blackman, H.S.

    1987-01-01

    A model developed by R.A. Fisher was applied to a set of Licensee Event Reports (LERs) summarizing transient initiating events at US commercial nuclear power plants. The empirical Bayes model was examined to study the feasibility of estimating the number of categories of transients which have not yet occurred at nuclear power plants. An examination of the model's predictive ability using an existing sample of data provided support for use of the model to estimate future transients. The estimate indicates that an approximate fifteen percent increase in the number of categories of transient initiating events may be expected during the period 1983--1993, assuming a stable process of transients. Limitations of the model and other possible applications are discussed. 10 refs., 1 fig., 3 tabs

  13. Application of Quantum Dots-Based Biotechnology in Cancer Diagnosis: Current Status and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Chun-Wei Peng

    2010-01-01

    Full Text Available The semiconductor nanocrystal quantum dots (QDs have excellent photo-physical properties, and the QDs-based probes have achieved encouraging developments in cellular and in vivo molecular imaging. More and more researches showed that QDs-based technology may become a promising approach in cancer research. In this review, we focus on recent application of QDs in cancer diagnosis and treatment, including early detection of primary tumor such as ovarian cancer, breast cancer, prostate cancer and pancreatic cancer, as well as regional lymph nodes and distant metastases. With the development of QDs synthesis and modification, the effect of QDs on tumor metastasis investigation will become more and more important in the future.

  14. Application of x-ray lasers to current and future experiments in atomic and molecular physics

    International Nuclear Information System (INIS)

    Caldwell, C. Denise

    1995-01-01

    The use of intrinsically narrow-banded, intense x-ray lasers has the potential for a significant impact in atomic and molecular physics. As with any new technology, it is impossible to predict all the new information which may emerge as the technology develops. At least at the beginning it will be important for these lasers to have applicability to existing experimental methods, which can then exploit the new tool for experiments which are currently barely feasible with existing and planned sources of radiation in the high-energy regime. Examples of these are: resonant Auger decay, particularly of dilute species, studied with electron spectrometry; multi-photon processes involving the simultaneous utilization of two laser photons; and fragmentation experiments in which the high-energy photon is one of a pump-probe pair. Results from these experiments will go a long way to suggesting directions for future study

  15. Permanent magnet Hall Thrusters development and applications on future brazilian space missions

    Science.gov (United States)

    Ferreira, Jose Leonardo; Martins, Alexandre A.; Miranda, Rodrigo; Schelling, Adriane; de Souza Alves, Lais; Gonçalves Costa, Ernesto; de Oliveira Coelho Junior, Helbert; Castelo Branco, Artur; de Oliveira Lopes, Felipe Nathan

    2015-10-01

    The Plasma Physics Laboratory (PPLUnB) has been developing a Permanent Magnet Hall Thruster (PHALL) for the Space Research Program for Universities (UNIESPAÇO), part of the Brazilian Space Activities Program (PNAE) since 2004. The PHALL project consists on a plasma source design, construction and characterization of the Hall type that will function as a plasma propulsion engine and characterized by several plasma diagnostics sensors. PHALL is based on a plasma source in which a Hall current is generated inside a cylindrical annular channel with an axial electric field produced by a ring anode and a radial magnetic field produced by permanent magnets. In this work it is shown a brief description of the plasma propulsion engine, its diagnostics instrumentation and possible applications of PHALL on orbit transfer maneuvering for future Brazilian geostationary satellite space missions.

  16. Elevated temperature properties of ferritic/martensitic steels for application to future nuclear reators

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Ji Hyun; Kim, Sung Ho; Ryu, Woo Seog; Chang, Jong Hwa

    2005-12-15

    The future nuclear systems such as nuclear hydrogen production reactors and fusion reactor require low activation and radiation embrittlement resistance in addition to excellent high temperature properties because their operating temperature are even higher than those of the light water reactors. The R and D of ferritic-martensitic steels in nuclear leading centuries like USA, Japan and EU has been continued for decades of years nuclear and they commercialized several steels. Korea consider modified 9Cr-1Mo steel as a candidate materials for reactor pressure vessel of very high temperature reactor. This state-of-the art report aimed to provide informations about the applicabilities of high Cr steels and low Cr steels through the analyses of their microstructures, mechanical properties and radiation characteristics. The metallurgical understanding of background of alloy evolutions might be helpful for the establishment of research orientation.

  17. An overview on the future trend of nuclear energy application and development in Indonesia

    International Nuclear Information System (INIS)

    Subki, M.H.; Aritomi, M.

    2001-01-01

    The purpose of this paper is to discuss the recent circumstances in Indonesia concerning nuclear energy program and try to anticipate the challenges and the future trend on the application of nuclear power for electricity generation. It is indispensable for Indonesia with regard to development of industries and improvement of the quality of life to establish sufficient and stable electric power supply. A national energy policy has been adopted, in its way to secure the continuity of energy supply at affordable price; to enhance the people's quality of life, and to reserve an adequate supply of oil and gas as important sources to fund national development program. It is expected that nuclear energy will reduce the dependence on a single type of fuel, economize energy utilization, as well as to support environmental program by applying clean-energy technology. (author)

  18. Essentials of single-cell analysis concepts, applications and future prospects

    CERN Document Server

    Santra, Tuhin

    2016-01-01

    This book provides an overview of single-cell isolation, separation, injection, lysis and dynamics analysis as well as a study of their heterogeneity using different miniaturized devices. As an important part of single-cell analysis, different techniques including electroporation, microinjection, optical trapping, optoporation, rapid electrokinetic patterning and optoelectronic tweezers are described in detail. It presents different fluidic systems (e.g. continuous micro/nano-fluidic devices, microfluidic cytometry) and their integration with sensor technology, optical and hydrodynamic stretchers etc., and demonstrates the applications of single-cell analysis in systems biology, proteomics, genomics, epigenomics, cancer transcriptomics, metabolomics, biomedicine and drug delivery systems. It also discusses the future challenges for single-cell analysis, including the advantages and limitations. This book is enjoyable reading material while at the same time providing essential information to scientists in acad...

  19. From wind ensembles to probabilistic information about future wind power production - results from an actual application

    DEFF Research Database (Denmark)

    Nielsen, Henrik Aalborg; Nielsen, Torben Skov; Madsen, Henrik

    2006-01-01

    horizon we aim at supplying quantiles of the wind power production conditional on the information available at the time at which the forecast is generated. This involves: (i) transformation of meteorological ensemble forecasts into wind power ensemble forecasts and (ii) calculation of quantiles based......Meteorological ensemble forecasts aim at quantifying the uncertainty of the future development of the weather by supplying several possible scenarios of this development. Here we address the use of such scenarios in probabilistic forecasting of wind power production. Specifically, for each forecast...... on the wind power ensemble forecasts. Given measurements of power production, representing a region or a single wind farm, we have developed methods applicable for these two steps. While (ii) should in principle be a simple task we found that the probabilistic information contained in the wind power ensembles...

  20. Current applications and future developments of positron emission tomography in head and neck cancer

    International Nuclear Information System (INIS)

    Lonneux, M.

    2005-01-01

    Positron emission tomography (PET-scan) is a well-established imaging modality in oncology. Using FDG, PET has also a wide range of applications in head and neck tumors for diagnosis, staging, monitoring of response to therapy, and detection of relapse. After a short technical introduction, the current indications of PET-FDG in head and neck tumors are reviewed. Present and future developments of PET are twofold: the use of new tracers for protein synthesis, cellular proliferation or detection of hypoxia etc., and the introduction of metabolic imaging as a adjunct to CT and MRI to determine target-volumes in radiation treatment planning. However, it has to be emphasized that a thorough clinical validation of the methods used is mandatory before their implementation in routine practice. (author)

  1. Estimation of cyclic interstory drift capacity of steel framed structures and future applications for seismic design.

    Science.gov (United States)

    Bojórquez, Edén; Reyes-Salazar, Alfredo; Ruiz, Sonia E; Terán-Gilmore, Amador

    2014-01-01

    Several studies have been devoted to calibrate damage indices for steel and reinforced concrete members with the purpose of overcoming some of the shortcomings of the parameters currently used during seismic design. Nevertheless, there is a challenge to study and calibrate the use of such indices for the practical structural evaluation of complex structures. In this paper, an energy-based damage model for multidegree-of-freedom (MDOF) steel framed structures that accounts explicitly for the effects of cumulative plastic deformation demands is used to estimate the cyclic drift capacity of steel structures. To achieve this, seismic hazard curves are used to discuss the limitations of the maximum interstory drift demand as a performance parameter to achieve adequate damage control. Then the concept of cyclic drift capacity, which incorporates information of the influence of cumulative plastic deformation demands, is introduced as an alternative for future applications of seismic design of structures subjected to long duration ground motions.

  2. Three-dimensional imaging and scanning: Current and future applications for pathology

    Directory of Open Access Journals (Sweden)

    Navid Farahani

    2017-01-01

    Full Text Available Imaging is vital for the assessment of physiologic and phenotypic details. In the past, biomedical imaging was heavily reliant on analog, low-throughput methods, which would produce two-dimensional images. However, newer, digital, and high-throughput three-dimensional (3D imaging methods, which rely on computer vision and computer graphics, are transforming the way biomedical professionals practice. 3D imaging has been useful in diagnostic, prognostic, and therapeutic decision-making for the medical and biomedical professions. Herein, we summarize current imaging methods that enable optimal 3D histopathologic reconstruction: Scanning, 3D scanning, and whole slide imaging. Briefly mentioned are emerging platforms, which combine robotics, sectioning, and imaging in their pursuit to digitize and automate the entire microscopy workflow. Finally, both current and emerging 3D imaging methods are discussed in relation to current and future applications within the context of pathology.

  3. Status and future application of pilot lead-bismuth target circuit TC-1 for ADS

    International Nuclear Information System (INIS)

    Ignatiev, S.; Leonchuk, M.; Orlov, Y.; Pankratov, D.; Reshetnikova, O.; Suvorov, G.; Zabudko, A.; Stepanov, V.; Klimov, N.; Hechanova, A.; Ma, J.; Li, N.; Gudowski, W.

    2007-01-01

    A complicated evolution, status and future application of the pilot molten lead-bismuth target circuit of 1 MW proton beam power (TC-1) as an important part of a target-blanket accelerator driven system (ADS), that has been developed, created and twice tested under the auspice of the International Science and Technology Center (ISTC), is analyzed. The target complex TC-1 is a circulation lead-bismuth loop whose beam window is made of ferritic steel EP-823 (this steel was used in the past as material of fuel rods cladding in reactors cooled with lead-bismuth). At present TC-1 is operating at coolant temperature up to 300 C degrees and will be used to study different issues linked to the use of lead-bismuth: -) interaction with air, water and hydrogen, -) different regimes of flow, -) corrosion, -) filtering, or -) slag formation

  4. Effects of Cosmetic Formulations Containing Hydroxyacids on Sun-Exposed Skin: Current Applications and Future Developments

    Directory of Open Access Journals (Sweden)

    Andrija Kornhauser

    2012-01-01

    Full Text Available This paper describes recent data on the effects of various skin formulations containing hydroxyacids (HAs and related products on sun-exposed skin. The most frequently used classes of these products, such as α- and β-hydroxyacids, polyhydroxy acids, and bionic acids, are reviewed, and their application in cosmetic formulations is described. Special emphasis is devoted to the safety evaluation of these formulations, particularly on the effects of their prolonged use on sun-exposed skin. We also discuss the important contribution of cosmetic vehicles in these types of studies. Data on the effects of HAs on melanogenesis and tanning are also included. Up-to-date methods and techniques used in those explorations, as well as selected future developments in the cosmetic area, are presented.

  5. Can the Future EnMAP Mission Contribute to Urban Applications? A Literature Survey

    Directory of Open Access Journals (Sweden)

    Andreas Müller

    2011-08-01

    Full Text Available With urban populations and their footprints growing globally, the need to assess the dynamics of the urban environment increases. Remote sensing is one approach that can analyze these developments quantitatively with respect to spatially and temporally large scale changes. With the 2015 launch of the spaceborne EnMAP mission, a new hyperspectral sensor with high signal-to-noise ratio at medium spatial resolution, and a 21 day global revisit capability will become available. This paper presents the results of a literature survey on existing applications and image analysis techniques in the context of urban remote sensing in order to identify and outline potential contributions of the future EnMAP mission. Regarding urban applications, four frequently addressed topics have been identified: urban development and planning, urban growth assessment, risk and vulnerability assessment and urban climate. The requirements of four application fields and associated image processing techniques used to retrieve desired parameters and create geo-information products have been reviewed. As a result, we identified promising research directions enabling the use of EnMAP for urban studies. First and foremost, research is required to analyze the spectral information content of an EnMAP pixel used to support material-based land cover mapping approaches. This information can subsequently be used to improve urban indicators, such as imperviousness. Second, we identified the global monitoring of urban areas as a promising field of investigation taking advantage of EnMAP’s spatial coverage and revisit capability. However, owing to the limitations of EnMAPs spatial resolution for urban applications, research should also focus on hyperspectral resolution enhancement to enable retrieving material information on sub-pixel level.

  6. Engaging the Applications Community of the future Surface Water and Ocean Topography (SWOT) Mission

    Science.gov (United States)

    Srinivasan, M.; Andral, A.; Dejus, M.; Hossain, F.; Peterson, C.; Beighley, E.; Pavelsky, T.; Chao, Y.; Doorn, B.; Bronner, E.; Houpert, L.

    2015-04-01

    NASA and the French space agency, CNES, with contributions from the Canadian Space Agency (CSA) and United Kingdom Space Agency (UKSA) are developing new wide swath altimetry technology that will cover most of the world's ocean and surface freshwater bodies. The proposed Surface Water and Ocean Topography (SWOT) mission will have the capability to make observations of surface water (lakes, rivers, wetland) heights and measurements of ocean surface topography with unprecedented spatial coverage, temporal sampling, and spatial resolution compared to existing technologies. These data will be useful for monitoring the hydrologic cycle, flooding, and characterizing human impacts on a changing environment. The applied science community is a key element in the success of the SWOT mission, demonstrating the high value of the science and data products in addressing societal issues and needs. The SWOT applications framework includes a working group made up of applications specialists, SWOT science team members, academics and SWOT Project members to promote applications research and engage a broad community of potential SWOT data users. A defined plan and a guide describing a program to engage early adopters in using proxies for SWOT data, including sophisticated ocean and hydrology simulators, an airborne analogue for SWOT (AirSWOT), and existing satellite datasets, are cornerstones for the program. A user survey is in development and the first user workshop was held in 2015, with annual workshops planned. The anticipated science and engineering advances that SWOT will provide can be transformed into valuable services to decision makers and civic organizations focused on addressing global disaster risk reduction initiatives and potential science-based mitigation activities for water resources challenges of the future. With the surface water measurements anticipated from SWOT, a broad range of applications can inform inland and coastal managers and marine operators of

  7. Applications of the automatic meter reading techniques at the Brazilian gas domestic market; Application des techniques de releve automatique des compteurs sur le marche domestique Bresilien du gaz

    Energy Technology Data Exchange (ETDEWEB)

    Venancio, J.; Monteiro, F. [Comgas, Sao Paulo (Brazil); D' Oliveira, R.D. [ORBIS, Curitiba (Brazil)

    2000-07-01

    This article will describe applications of the automation and automatic meter reading techniques at the internal gas pipes installations design, considering residential and commercial buildings, and taking in account the tendency of rapid growth of the activities related to the natural gas industry in Brazil, as well as the recently development of new technologies that can be applied with affordable prices. It will be analysed the application of an automatic meter reading technology in a building of several floors in Sao Paulo, which gas installations design is being carried up, with be purpose of making a comparative cost-effectiveness study with the traditional constructive methods applied in Brazil. As a result, it will be purposed a new commercialization model for the gas in Brazil at the residential and commercial market. (authors)

  8. Associations between Otolaryngology Applicant Characteristics and Future Performance in Residency or Practice: A Systematic Review.

    Science.gov (United States)

    Bowe, Sarah N; Laury, Adrienne M; Gray, Stacey T

    2017-06-01

    Objective This systematic review aims to evaluate which applicant characteristics available to an otolaryngology selection committee are associated with future performance in residency or practice. Data Sources PubMed, Scopus, ERIC, Health Business, Psychology and Behavioral Sciences Collection, and SocINDEX. Review Methods Study eligibility was performed by 2 independent investigators in accordance with the PRISMA protocol (Preferred Reporting Items for Systematic Reviews and Meta-analyses). Data obtained from each article included research questions, study design, predictors, outcomes, statistical analysis, and results/findings. Study bias was assessed with the Quality in Prognosis Studies tool. Results The initial search identified 439 abstracts. Six articles fulfilled all inclusion and exclusion criteria. All studies were retrospective cohort studies (level 4). Overall, the studies yielded relatively few criteria that correlated with residency success, with generally conflicting results. Most studies were found to have a high risk of bias. Conclusion Previous resident selection research has lacked a theoretical background, thus predisposing this work to inconsistent results and high risk of bias. The included studies provide historical insight into the predictors and criteria (eg, outcomes) previously deemed pertinent by the otolaryngology field. Additional research is needed, possibly integrating aspects of personnel selection, to engage in an evidence-based approach to identify highly qualified candidates who will succeed as future otolaryngologists.

  9. CRISPR-Cas9 for medical genetic screens: applications and future perspectives.

    Science.gov (United States)

    Xue, Hui-Ying; Ji, Li-Juan; Gao, Ai-Mei; Liu, Ping; He, Jing-Dong; Lu, Xiao-Jie

    2016-02-01

    CRISPR-Cas9 (clustered regularly interspaced short palindromic repeats-CRISPR associated nuclease 9) systems have emerged as versatile and convenient (epi)genome editing tools and have become an important player in medical genetic research. CRISPR-Cas9 and its variants such as catalytically inactivated Cas9 (dead Cas9, dCas9) and scaffold-incorporating single guide sgRNA (scRNA) have been applied in various genomic screen studies. CRISPR screens enable high-throughput interrogation of gene functions in health and diseases. Compared with conventional RNAi screens, CRISPR screens incur less off-target effects and are more versatile in that they can be used in multiple formats such as knockout, knockdown and activation screens, and can target coding and non-coding regions throughout the genome. This powerful screen platform holds the potential of revolutionising functional genomic studies in the near future. Herein, we introduce the mechanisms of (epi)genome editing mediated by CRISPR-Cas9 and its variants, introduce the procedures and applications of CRISPR screen in functional genomics, compare it with conventional screen tools and at last discuss current challenges and opportunities and propose future directions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  10. Recent Development Activities and Future Mission Applications of NASA's Evolutionary Xenon Thruster (NEXT)

    Science.gov (United States)

    Patterson, Michael J.; Pencil, Eric J.

    2014-01-01

    NASAs Evolutionary Xenon Thruster (NEXT) project is developing next generation ion propulsion technologies to enhance the performance and lower the costs of future NASA space science missions. This is being accomplished by producing Engineering Model (EM) and Prototype Model (PM) components, validating these via qualification-level and integrated system testing, and preparing the transition of NEXT technologies to flight system development. This presentation is a follow-up to the NEXT project overviews presented in 2009-2010. It reviews the status of the NEXT project, presents the current system performance characteristics, and describes planned activities in continuing the transition of NEXT technology to a first flight. In 2013 a voluntary decision was made to terminate the long duration test of the NEXT thruster, given the thruster design has exceeded all expectations by accumulating over 50,000 hours of operation to demonstrate around 900 kg of xenon throughput. Besides its promise for upcoming NASA science missions, NEXT has excellent potential for future commercial and international spacecraft applications.

  11. Application of stem cell-derived retinal pigmented epithelium in retinal degenerative diseases: present and future.

    Science.gov (United States)

    Luo, Mingyue; Chen, Youxin

    2018-01-01

    As a constituent of blood-retinal barrier and retinal outer segment (ROS) scavenger, retinal pigmented epithelium (RPE) is fundamental to normal function of retina. Malfunctioning of RPE contributes to the onset and advance of retinal degenerative diseases. Up to date, RPE replacement therapy is the only possible method to completely reverse retinal degeneration. Transplantation of human RPE stem cell-derived RPE (hRPESC-RPE) has shown some good results in animal models. With promising results in terms of safety and visual improvement, human embryonic stem cell-derived RPE (hESC-RPE) can be expected in clinical settings in the near future. Despite twists and turns, induced pluripotent stem cell-derived RPE (iPSC-RPE) is now being intensely investigated to overcome genetic and epigenetic instability. By far, only one patient has received iPSC-RPE transplant, which is a hallmark of iPSC technology development. During follow-up, no major complications such as immunogenicity or tumorigenesis have been observed. Future trials should keep focusing on the safety of stem cell-derived RPE (SC-RPE) especially in long period, and better understanding of the nature of stem cell and the molecular events in the process to generate SC-RPE is necessary to the prosperity of SC-RPE clinical application.

  12. Future of clip-on weapon sights: pros and cons from an applications perspective

    Science.gov (United States)

    Knight, C. Reed; Greenslade, Ken; Francisco, Glen

    2015-05-01

    US Domestic, International, allied Foreign National Warfighters and Para-Military First Responders (Police, SWAT, Special Operations, Law Enforcement, Government, Security and more) are put in harm's way all the time. To successfully complete their missions and return home safely are the primary goals of these professionals. Tactical product improvements that affect mission effectiveness and solider survivability are pivotal to understanding the past, present and future of Clip-On in-line weapon sights. Clip-On Weapon Sight (WS) technology was deemed an interim solution by the US Government for use until integrated and fused (day/night multi-sensor) Weapon Sights (WSs) were developed/fielded. Clip-On has now become the solution of choice by Users, Warriors, Soldiers and the US Government. SWaP-C (size, weight and power -cost) has been improved through progressive advances in Clip-On Image Intensified (I2), passive thermal, LL-CMOS and fused technology. Clip-On Weapon Sights are now no longer mounting position sensitive. Now they maintain aim point boresight, so they can be used for longer ranges with increased capabilities while utilizing the existing zeroed weapon and daysight optic. Active illuminated low-light level (both analog I2 and digital LL-CMOS) imaging is rightfully a real-world technology, proven to deliver daytime and low-light level identification confidence. Passive thermal imaging is also a real-world technology, proven to deliver daytime, nighttime and all-weather (including dirty battlefield) target detection confidence. Image processing detection algorithms with intelligent analytics provide documented promise to improve confidence by reducing Users, Warriors and Soldiers' work-loads and improving overall system engagement solution outcomes. In order to understand the future of Clip-On in-line weapon sights, addressing pros and cons, this paper starts with an overview of historical weapon sight applications, technologies and stakeholder decisions

  13. Study of beam spin asymmetry during photon electro-production near the CLAS spectrometer at the Jefferson Lab and development of Micromegas sensors for the future CLAS12 spectrometer; Etude de l'asymetrie de spin du faisceau dans l'electroproduction de photons aupres du spectrometre CLAS au Jefferson Lab et developpement de detecteurs Micromegas pour le futur spectrometre CLAS12

    Energy Technology Data Exchange (ETDEWEB)

    Konczykowski, Piotr

    2010-12-17

    After having discussed the theoretical aspects of the study of the nucleon structure with the introduction of the Generalized Parton Distributions, this research thesis proposes an overview of the Jefferson Lab and describes the different components of the CLAS spectrometer. The author details the experiment, the calibration of the different apparatus. He analyzes the obtained data and comments the beam spin asymmetries. He details the energy rise project for the Jefferson Lab, presents the future spectrometer and the expected results. He finally reports the development of Micromegas sensors for this new spectrometer, and results obtained in magnetic fields (1, 5 T in Saclay and 4, 5 T in the Jefferson Lab) which validate the use of Micromegas in a high transverse magnetic field

  14. Établissements recevant du public

    CERN Document Server

    2014-01-01

    Synthèse pour les installations électriques, des règles de sécurité contre les risques d’incendie et de panique dans les établissements recevant du public (ERP), selon l’arrêté du 25 juin 1980 modifié. L'ouvrage traite à la fois des dispositions communes aux établissements du 1er groupe (1ère à 4ème catégorie), du 2ème groupe (5ème catégorie) et des règles particulières applicables aux différents types d'établissements (structures d'accueil pour personnes âgées ou handicapées, hôtels, magasins de vente, restaurants et débit de boisson, établissements de soins, administration, châpiteaux, etc...) Sont ainsi notamment traités, dans le cadre des dispositions communes aux établissements du 1er groupe, pour les installations électriques normales : les installations des appareils, tableaux et canalisations, les locaux électriques et installation de machines, l'éclairage normal des locaux accessibles au public, le chauffage et la ventilation, l'installation d'eau chaude sanita...

  15. Theory and application for the promotion of wheat production in China: past, present and future.

    Science.gov (United States)

    Xu, Zhenzhu; Yu, Zhenwen; Zhao, Junye

    2013-08-15

    Food security is becoming a crucial concern worldwide. In this study, we focus on wheat - a staple crop in China - as a model to review its history, status quo and future scenarios, with regard to key production technologies and management practices for wheat production and associated food security issues since the new era in China: the post-1949 era. First, the dominant technologies and management practices over the past 60 years are reviewed. Secondly, we outline several key innovative technologies and their theoretical bases over the last decade, including (i) prohibiting excessively early senescence at a later growth stage to maintain viable leaves with higher photosynthetic capacity, (ii) postponing top dressing nitrogen application to balance carbon and nitrogen nutrition, and (iii) achieving both high yield and better grain quality mainly by increasing soil productivity and balancing the ratio of nutrient elements. Finally, concerns such as water shortages and excessive application of chemical fertilizers are presented. Nevertheless, under high negative conditions, including global warming, rapid population growth, decreasing amounts of arable land, increasing competition with cash crops and severe environmental pollution, we conclude that domestic food production will be able to meet Chinese demand in the mid to long term, because increasingly innovative technologies and improved management practices have been and may continue to be applied appropriately. © 2013 Society of Chemical Industry.

  16. The future of diode pumped solid state lasers and their applicability to the automotive industry

    Science.gov (United States)

    Solarz, R.; Beach, R.; Hackel, L.

    1994-03-01

    The largest commercial application of high power lasers is for cutting and welding. Their ability to increase productivity by introducing processing flexibility and integrated automation into the fabrication process is well demonstrated. This paper addresses the potential importance of recent developments in laser technology to further impact their use within the automotive industry. The laser technology we will concentrate upon is diode laser technology and diode-pumped solid-state laser technology. We will review present device performance and cost and make projections for the future in these areas. Semiconductor laser arrays have matured dramatically over the last several years. They are lasers of unparalleled efficiency (greater than 50%), reliability (greater than 10,000 hours of continuous operation), and offer the potential of dramatic cost reductions (less than a dollar per watt). They can be used directly in many applications or can be used to pump solid-state lasers. When used as solid-state laser pump arrays, they simultaneously improve overall laser efficiency, reduce size, and improve reliability.

  17. Potential applications of advanced remote handling and maintenance technology to future waste handling facilities

    International Nuclear Information System (INIS)

    Kring, C.T.; Herndon, J.N.; Meacham, S.A.

    1987-01-01

    The Consolidated Fuel Reprocessing Program (CFRP) at the Oak Ridge National Laboratory (ORNL) has been advancing the technology in remote handling and remote maintenance of in-cell systems planned for future US nuclear fuel reprocessing plants. Much of the experience and technology developed over the past decade in this endeavor are directly applicable to the in-cell systems being considered for the facilities of the Federal Waste Management System (FWMS). The ORNL developments are based on the application of teleoperated force-reflecting servomanipulators controlled by an operator completely removed from the hazardous environment. These developments address the nonrepetitive nature of remote maintenance in the unstructured environments encountered in a waste handling facility. Employing technological advancements in dexterous manipulators, as well as basic design guidelines that have been developed for remotely maintained equipment and processes, can increase operation and maintenance system capabilities, thereby allowing the attainment of two Federal Waste Management System major objectives: decreasing plant personnel radiation exposure and increasing plant availability by decreasing the mean-time-to-repair in-cell maintenance and process equipment

  18. Potential applications of advanced remote handling and maintenance technology to future waste handling facilities

    International Nuclear Information System (INIS)

    Kring, C.T.; Herndon, J.N.; Meacham, S.A.

    1987-01-01

    The Consolidated Fuel Reprocessing Program (CFRP) at the Oak Ridge National Laboratory (ORNL) has been advancing the technology in remote handling and remote maintenance of in-cell systems planned for future U.S. nuclear fuel reprocessing plants. Much of the experience and technology developed over the past decade in this endeavor are directly applicable to the in-cell systems being considered for the facilities of the Federal Waste Management System (FWMS). The ORNL developments are based on the application of teleoperated force-reflecting servomanipulators controlled by an operator completely removed from the hazardous environment. These developments address the nonrepetitive nature of remote maintenance in the unstructured environments encountered in a waste handling facility. Employing technological advancements in dexterous manipulators, as well as basic design guidelines that have been developed for remotely maintained equipment and processes, can increase operation and maintenance system capabilities, thereby allowing the attainment of two Federal Waste Management System major objectives: decreasing plant personnel radiation exposure and increasing plant availability by decreasing the mean-time-to-repair in-cell maintenance and process equipment

  19. Kelvin probe force microscopy for characterizing doped semiconductors for future sensor applications in nano- and biotechnology

    International Nuclear Information System (INIS)

    Schmidt, Heidemarie; Habicht, Stefan; Feste, Sebastian; Müller, Anne-Dorothea; Schmidt, Oliver G.

    2013-01-01

    Kelvin probe force microscopy (KPFM) is one of the most promising non-contact electrical nanometrology techniques to characterize doped semiconductors. By applying a recently introduced explanation of measured KPFM signals, we show the applicability of KPFM to determine and control surface-near electrostatic forces in planar doped silicon and in doped silicon nanostructures. Surface-near electrostatic forces may be used for the immobilization of nano- and biomaterials in future sensor applications in nano- and biotechnology. Additionally, the influence of the electrostatic potential distribution in doped semiconductor nanostructures, e.g. in horizontal Si nanowires, and its influence on the surface-near electrostatic forces are discussed. It is explained how drift and diffusion of injected electrons and holes in intrinsic electric fields influence the detected KPFM signal. For example KPFM is successfully employed to locate p + p and n + p junctions along B-doped and As-doped p-Si nanowires, respectively. As an outlook the physical immobilization and the transport of biomaterials above arrays of separately addressable doped semiconductor cells will be discussed.

  20. Thermoluminescent properties of CVD diamond: applications to ionising radiation dosimetry; Proprietes thermoluminescentes du diamant CVD: applications a la dosimetrie des rayonnements ionisants

    Energy Technology Data Exchange (ETDEWEB)

    Petitfils, A

    2007-09-15

    Remarkable properties of synthetic diamond (human soft tissue equivalence, chemical stability, non-toxicity) make this material suitable for medical application as thermoluminescent dosimeter (TLD). This work highlights the interest of this material as radiotherapy TLD. In the first stage of this work, we looked after thermoluminescent (TL) and dosimetric properties of polycrystalline diamond made by Chemically Vapor Deposited (CVD) synthesis. Dosimetric characteristics are satisfactory as TLD for medical application. Luminescence thermal quenching on diamond has been investigated. This phenomenon leads to a decrease of dosimetric TL peak sensitivity when the heating rate increases. The second part of this work analyses the use of synthetic diamond as TLD in radiotherapy. Dose profiles, depth dose distributions and the cartography of an electron beam obtained with our samples are in very good agreement with results from an ionisation chamber. It is clearly shown that CVD) diamond is of interest to check beams of treatment accelerators. The use of these samples in a control of treatment with Intensity Modulated Radiation Therapy underlines good response of synthetic diamond in high dose gradient areas. These results indicate that CVD diamond is a promising material for radiotherapy dosimetry. (author)

  1. APPLICATION DU MODELE "DEFECT POOL" POUR LA SIMULATION DE LA PHOTOCONDUCTIVITE TRANSITOIRE DANS LE a-Si:H INTRINSEQUE ET DOPE PAR LE PHOSPHORE

    Directory of Open Access Journals (Sweden)

    A.F MEFTAH

    2004-06-01

    Full Text Available Le profil d'énergie de la densité des états le long du gap du a-Si:H est déterminé conjointement par le modèle defect pool (MDP et la queue de bande de conduction (QBC calculée par la transformé de Fourier de la photoconductivité transitoire (PCT. La PCT obtenue par la simulation numérique est comparée avec les données expérimentales pour le cas du a-Si:H intrinsèque et le a-Si:H dopé par le phosphore. Les caractéristiques observées dans les courbes de la PCT à différentes températures permettent de calculer la fréquence d'émission au bord de la mobilité, le minimum de la queue de la QBC dans le a-Si:H intrinsèque et le pic de la bande des donneur dans le a-Si:H dopé .

  2. Industrial applications of solar energy: deserts, seas, the Alps; Les applications industrielles de l'energie solaire: du desert aux Alpes en passant par la mer

    Energy Technology Data Exchange (ETDEWEB)

    Allani, Y.

    2008-07-01

    In this set of presentation slides, after a review of worldwide energy resources the author presents his innovative technical solution aimed at contributing to future energy supply. An extra-flat solar concentrator was developed to produce industrial steam in the temperature range 150 to 300 {sup o}C. A prototype was operated on the site of the Federal Institute of Technology (EPFL) in Lausanne, Switzerland, for power generation at 12 kW{sub el}. In Ras al Khaimah, United Arab Emirates, the concept of the so-called Solar Island is to be tested. Construction work is underway. A floating circular platform will be equipped with parallel rows of extra-flat solar concentrators. The platform will rotate to follow the sun apparent movement and enhance the power output of the concentrators. A second project is presented that should be realised in the Swiss Alps. In this case the extra-flat concentrators will be mounted on existing steel constructions that prevent snow avalanches on steep grounds. The basic technical data of the two projects are given.

  3. Modelization, fabrication and evaluation avalanche photodiodes polarized in Geiger mode for the single photon in astrophysics applications; Modelisation, fabrication et evaluation des photodiodes a avalanche polarisees en mode Geiger pour la detection du photon unique dans les applications Astrophysiques

    Energy Technology Data Exchange (ETDEWEB)

    Pellion, D

    2008-12-15

    The genesis of the work presented in this this is in the field of very high energy astrophysics. One century ago, scientists identified a new type of messenger coming from space: cosmic rays. This radiation consists of particles (photons or other) of very high energy which bombard the Earth permanently. The passage of cosmic radiations in the Earth's atmosphere results in the creation of briefs luminous flashes (5 ns) of very low intensity (1 pW), a Cherenkov flash, and then becomes visible on the ground. In the current state of the art the best detector of light today is the Photomultiplier tube (PMT), thanks to its characteristics of sensitivity and speed. But there are some drawbacks: low quantum efficiency, cost, weight etc. We present in this thesis a new alternative technology: silicon photon counters, made of photodiodes polarized in Geiger mode. This operating mode makes it possible to obtain an effect of multiplication comparable to that of the PMT. A physical and electrical model was developed to reproduce the behaviour of this detector. We then present in this thesis work an original technological process allowing the realization of these devices in the Center of Technology of LAAS-CNRS, with the simulation of each operation of the process. We developed a scheme for the electric characterization of the device, from the static mode to the dynamic mode, in order to check conformity with SILVACO simulations and to the initial model. Results are already excellent, given this is only a first prototype step, and comparable with the results published in the literature. These silicon devices can intervene in all the applications where there is a photomultiplier and replace it. The applications are thus very numerous and the growth of the market of these detectors is very fast. We present a first astrophysical experiment installed at the 'Pic du Midi' site which has detected Cherenkov flashes from cosmic rays with this new semiconductor technology

  4. Effet du Pediococcus acidilactici sur le bilan lipidique sanguin du ...

    African Journals Online (AJOL)

    Les résultats relatifs aux performances zootechniques ont montré que l'addition du probiotique a amélioré significativement le gain de poids pendant la phase de croissance se traduisant par un indice de consommation meilleur. Les dosages du cholestérol total, des triglycérides, du HDL et du LDL ont été déterminés à la ...

  5. Emulation of long-term changes in global climate: application to the late Pliocene and future

    Directory of Open Access Journals (Sweden)

    N. S. Lord

    2017-11-01

    Full Text Available Multi-millennial transient simulations of climate changes have a range of important applications, such as for investigating key geologic events and transitions for which high-resolution palaeoenvironmental proxy data are available, or for projecting the long-term impacts of future climate evolution on the performance of geological repositories for the disposal of radioactive wastes. However, due to the high computational requirements of current fully coupled general circulation models (GCMs, long-term simulations can generally only be performed with less complex models and/or at lower spatial resolution. In this study, we present novel long-term continuous projections of climate evolution based on the output from GCMs, via the use of a statistical emulator. The emulator is calibrated using ensembles of GCM simulations, which have varying orbital configurations and atmospheric CO2 concentrations and enables a variety of investigations of long-term climate change to be conducted, which would not be possible with other modelling techniques on the same temporal and spatial scales. To illustrate the potential applications, we apply the emulator to the late Pliocene (by modelling surface air temperature – SAT, comparing its results with palaeo-proxy data for a number of global sites, and to the next 200 kyr (thousand years (by modelling SAT and precipitation. A range of CO2 scenarios are prescribed for each period. During the late Pliocene, we find that emulated SAT varies on an approximately precessional timescale, with evidence of increased obliquity response at times. A comparison of atmospheric CO2 concentration for this period, estimated using the proxy sea surface temperature (SST data from different sites and emulator results, finds that relatively similar CO2 concentrations are estimated based on sites at lower latitudes, whereas higher-latitude sites show larger discrepancies. In our second illustrative application, spanning the next

  6. QUELLE EVOLUTION DE LA SITUATION DU MARCHE DU ...

    African Journals Online (AJOL)

    Moun

    industrie et de l'énergie. Ces projets renfermaient un poten- tiel puissant de dynamique de ...... marché du travail segmenté : une analyse appliquée au cas du Maroc»,. Document de travail n°18. Groupe d'Economie du Développement de.

  7. Results of experimental testing of system of future physical culture teachers’ training for art pedagogic means’ application in pedagogic functioning

    Directory of Open Access Journals (Sweden)

    T.V. Nizhevska

    2015-10-01

    Full Text Available Purpose: the research is devoted to seeking of ways to rising of quality of future physical culture teachers. Material: in experiment 436 students and 29 teachers participated. Results: it was found that readiness of future physical culture teachers for application of art pedagogic means in professional functioning is achieved through realization of appropriate block system. Such system ensures mastering by students of the following: theoretical principles of art pedagogic; mastering of art pedagogic skills in teaching and quasi professional functioning; acquiring of practical experience of art means’ application in period of pedagogic practice at schools. It was also determined that training system of future teachers includes the following three blocks: conceptual-target, knowledge-procedural; control-correcting. Conclusions: it is recommended to use such criteria of students’ readiness for application of art means in pedagogic functioning: motivation-axiological, cognitive-active, personality’s-reflexive.

  8. E-learning tools for education: regulatory aspects, current applications in radiology and future prospects.

    Science.gov (United States)

    Pinto, A; Selvaggi, S; Sicignano, G; Vollono, E; Iervolino, L; Amato, F; Molinari, A; Grassi, R

    2008-02-01

    E-learning, an abbreviation of electronic learning, indicates the provision of education and training on the Internet or the World Wide Web. The impact of networks and the Internet on radiology is undoubtedly important, as it is for medicine as a whole. The Internet offers numerous advantages compared with other mass media: it provides access to a large amount of information previously known only to individual specialists; it is flexible, permitting the use of images or video; and it allows linking to Web sites on a specific subject, thus contributing to further expand knowledge. Our purpose is to illustrate the regulatory aspects (including Internet copyright laws), current radiological applications and future prospects of e-learning. Our experience with the installation of an e-learning platform is also presented. We performed a PubMed search on the published literature (without time limits) dealing with e-learning tools and applications in the health sector with specific reference to radiology. The search included all study types in the English language with the following key words: e-learning, education, teaching, online exam, radiology and radiologists. The Fiaso study was referred to for the regulatory aspects of e-learning. The application of e-learning to radiology requires the development of a model that involves selecting and creating e-learning platforms, creating and technologically adapting multimedia teaching modules, creating and managing a unified catalogue of teaching modules, planning training actions, defining training pathways and Continuing Education in Medicine (CME) credits, identifying levels of teaching and technological complexity of support tools, sharing an organisational and methodological model, training the trainers, operators' participation and relational devices, providing training, monitoring progress of the activities, and measuring the effectiveness of training. Since 2004, a platform--LiveLearning--has been used at our

  9. Étude du profil cytokinique de patients atteints d’hydatidose : une possible application en matière d’immunosurveillance

    Directory of Open Access Journals (Sweden)

    Mezioug D.

    2009-03-01

    Full Text Available L’hydatidose est une zoonose endémique en Algérie et dans les pays du Maghreb. L’objectif de notre travail a porté sur l’exploration des cytokines exprimées dans le parcours des réponses immunitaires au cours de l’infection par Echinococcus granulosus. Cette étude a été réalisée en vue de situer l’implication du rapport Th1/Th2 dans l’évolution de la pathologie en fonction de la localisation anatomique du kyste, le stade et l’évolution clinique. Un dosage de l’interféron-γ (IFN-γ, de l’interleukine-12 (Il-12, de l’interleukine-16 (Il-16, de l’interleukine-18 (Il-18, de l’interleukine-4 (Il-4, de l’interleukine-5 (Il-5, de l’interleukine-10 (Il-10 et de l’interleukine-13 (Il-13 dans les sérums de patients algériens (n = 177 porteurs de kystes hydatiques au niveau hépatique, pulmonaire, hépatique et pulmonaire associés, splénique, rénale, osseux, cardiaque et multiples a été entrepris. L’analyse du profil des cytokines a été également réalisée chez les patients présentant des formes à complication (fissuration du kyste, rupture, calcification du kyste et les patients en phase de récidive et selon le stade clinique (pré- et post-opératoire. L’identification et l’évaluation des activités des cytokines considérées ont été réalisées par un dosage immuno-enzymatique (ELISA sandwich selon les méthodes préconisées par immunotech (France. Des teneurs significatives en IFN-γ, Il-12, Il-16, Il-18, Il-4, Il-5, Il-10 et Il-13 ont été détectées dans les sérums des patients en comparaison aux sujets “contrôles” (p < 0,001, suggérant la coexistence des deux voies Th1 et Th2 dans le mécanisme de défense mis en jeu par l’homme au cours de l’évolution de la parasitose. La comparaison des niveaux de production de ces médiateurs en fonction de la localisation anatomique des kystes montre que les teneurs sériques en IFN-γ, Il-12, Il-16 et Il-18, mesurées chez

  10. Cone beam computed tomographic imaging: perspective, challenges, and the impact of near-trend future applications.

    Science.gov (United States)

    Cavalcanti, Marcelo Gusmão Paraiso

    2012-01-01

    Cone beam computed tomography (CBCT) can be considered as a valuable imaging modality for improving diagnosis and treatment planning to achieve true guidance for several craniofacial surgical interventions. A new concept and perspective in medical informatics is the highlight discussion about the new imaging interactive workflow. The aim of this article was to present, in a short literature review, the usefulness of CBCT technology as an important alternative imaging modality, highlighting current practices and near-term future applications in cutting-edge thought-provoking perspectives for craniofacial surgical assessment. This article explains the state of the art of CBCT improvements, medical workstation, and perspectives of the dedicated unique hardware and software, which can be used from the CBCT source. In conclusion, CBCT technology is developing rapidly, and many advances are on the horizon. Further progress in medical workstations, engineering capabilities, and improvement in independent software-some open source-should be attempted with this new imaging method. The perspectives, challenges, and pitfalls in CBCT will be delineated and evaluated along with the technological developments.

  11. Insights into cerumen and application in diagnostics: past, present and future prospective.

    Science.gov (United States)

    Shokry, Engy; Filho, Nelson Roberto Antoniosi

    2017-10-15

    Cerumen or earwax is an emerging bio-fluid in clinical diagnosis that has been very little exploited during the past decades in spite of its high diagnostic potential. It is highly abundant in diagnostic biomarkers such as genetic material, lipids, proteins, chemical elements, internal and external metabolites ( e.g. hormones, volatile organic compounds, amino acids, xenobiotics etc. ) reaching earwax from the blood circulation. Thus, it is able to reflect not only physiology, pathophysiology of the human body but can also detect recent and long term exposure to environmental pollutants, without the need of invasive blood tests and in the same time overcoming many disadvantages faced by using other diagnostic biological fluids. This review discusses the biology, functions, chemistry of earwax, past and current approaches for the study of its chemical composition, emphasizing how a detected variation in its composition can offer information of high clinical value, which can be useful in diagnosis of many diseases such as metabolic disorders and tumours as well as in forensic applications. It also presents details about techniques of sample collection, storage, and analysis. Moreover, it highlights concerns about the use of earwax for diagnostic purposes, which should be addressed to make earwax diagnostics a reality in the future.

  12. Current and Future Applications of Biomedical Engineering for Proteomic Profiling: Predictive Biomarkers in Neuro-Traumatology

    Directory of Open Access Journals (Sweden)

    Mario Ganau

    2018-02-01

    Full Text Available This systematic review aims to summarize the impact of nanotechnology and biomedical engineering in defining clinically meaningful predictive biomarkers in patients with traumatic brain injury (TBI, a critical worldwide health problem with an estimated 10 billion people affected annually worldwide. Data were collected through a review of the existing English literature performed on Scopus, MEDLINE, MEDLINE in Process, EMBASE, and/or Cochrane Central Register of Controlled Trials. Only experimental articles revolving around the management of TBI, in which the role of new devices based on innovative discoveries coming from the field of nanotechnology and biomedical engineering were highlighted, have been included and analyzed in this study. Based on theresults gathered from this research on innovative methods for genomics, epigenomics, and proteomics, their future application in this field seems promising. Despite the outstanding technical challenges of identifying reliable biosignatures for TBI and the mixed nature of studies herein described (single cells proteomics, biofilms, sensors, etc., the clinical implementation of those discoveries will allow us to gain confidence in the use of advanced neuromonitoring modalities with a potential dramatic improvement in the management of those patients.

  13. Management and control applications in Agriculture domain via a Future Internet Business-to-Business platform

    Directory of Open Access Journals (Sweden)

    Sokratis Barmpounakis

    2015-05-01

    Full Text Available The Agriculture business domain, as a vital part of the overall supply chain, is expected to highly evolve in the upcoming years via the developments, which are taking place on the side of the Future Internet. This paper presents a novel Business-to-Business collaboration platform from the agri-food sector perspective, which aims to facilitate the collaboration of numerous stakeholders belonging to associated business domains, in an effective and flexible manner. The contemporary B2B collaboration schemes already place the requirements for swift deployment of cloud applications, capable of both integrating diverse legacy systems, as well as developing in a rapid way new services and systems, which will be able to instantly communicate and provide complete, “farm-to-fork” solutions for farmers, agri-food and logistics service providers, ICT companies, end-product producers, etc. To this end, this conceptual paper describes how these requirements are addressed via the FIspace B2B platform, focusing on the Greenhouse Management & Control scenarios.

  14. Fluorescence detection, enumeration and characterization of single circulating cells in vivo: technology, applications and future prospects

    Science.gov (United States)

    Hartmann, Carolin; Patil, Roshani; Lin, Charles P.; Niedre, Mark

    2018-01-01

    There are many diseases and biological processes that involve circulating cells in the bloodstream, such as cancer metastasis, immunology, reproductive medicine, and stem cell therapies. This has driven significant interest in new technologies for the study of circulating cells in small animal research models and clinically. Most currently used methods require drawing and enriching blood samples from the body, but these suffer from a number of limitations. In contrast, ‘in vivo flow cytometry’ (IVFC) refers to set of technologies that allow study of cells directly in the bloodstream of the organism in vivo. In recent years the IVFC field has grown significantly and new techniques have been developed, including fluorescence microscopy, multi-photon, photo-acoustic, and diffuse fluorescence IVFC. In this paper we review recent technical advances in IVFC, with emphasis on instrumentation, contrast mechanisms, and detection sensitivity. We also describe key applications in biomedical research, including cancer research and immunology. Last, we discuss future directions for IVFC, as well as prospects for broader adoption by the biomedical research community and translation to humans clinically.

  15. Smartphone applications with sensors used in a tertiary hospital-current status and future challenges.

    Science.gov (United States)

    Park, Yu Rang; Lee, Yura; Lee, Guna; Lee, Jae Ho; Shin, Soo-Yong

    2015-04-27

    Smartphones have been widely used recently to monitor heart rate and activity, since they have the necessary processing power, non-invasive and cost-effective sensors, and wireless communication capabilities. Consequently, healthcare applications (apps) using smartphone-based sensors have been highlighted for non-invasive physiological monitoring. In addition, several healthcare apps have received FDA clearance. However, in spite of their potential, healthcare apps with smartphone-based sensors are mostly used outside of hospitals and have not been widely adopted for patient care in hospitals until recently. In this paper, we describe the experience of using smartphone apps with sensors in a large medical center in Korea. Among >20 apps developed in our medical center, four were extensively analyzed ("My Cancer Diary", "Point-of-Care HIV Check", "Blood Culture" and "mAMIS"), since they use smartphone-based sensors such as the camera and barcode reader to enter data into the electronic health record system. By analyzing the usage patterns of these apps for data entry with sensors, the current limitations of smartphone-based sensors in a clinical setting, hurdles against adoption in the medical center, benefits of smartphone-based sensors and potential future research directions could be evaluated.

  16. Smartphone Applications with Sensors Used in a Tertiary Hospital—Current Status and Future Challenges

    Directory of Open Access Journals (Sweden)

    Yu Rang Park

    2015-04-01

    Full Text Available Smartphones have been widely used recently to monitor heart rate and activity, since they have the necessary processing power, non-invasive and cost-effective sensors, and wireless communication capabilities. Consequently, healthcare applications (apps using smartphone-based sensors have been highlighted for non-invasive physiological monitoring. In addition, several healthcare apps have received FDA clearance. However, in spite of their potential, healthcare apps with smartphone-based sensors are mostly used outside of hospitals and have not been widely adopted for patient care in hospitals until recently. In this paper, we describe the experience of using smartphone apps with sensors in a large medical center in Korea. Among >20 apps developed in our medical center, four were extensively analyzed (“My Cancer Diary”, “Point-of-Care HIV Check”, “Blood Culture” and “mAMIS”, since they use smartphone-based sensors such as the camera and barcode reader to enter data into the electronic health record system. By analyzing the usage patterns of these apps for data entry with sensors, the current limitations of smartphone-based sensors in a clinical setting, hurdles against adoption in the medical center, benefits of smartphone-based sensors and potential future research directions could be evaluated.

  17. fibrosarcome du larynx

    African Journals Online (AJOL)

    pie du lit tumoral est employée comme complément thé- rapeutique [9] alors que la chimiothérapie est générale- ment indiquée dans les formes métastatiques. Le pronos- tic dépend essentiellement du degré de différentiation his- tologique. En fait, le fibrosarcome bien différencié est caractérisé par la fréquence de récidive ...

  18. Petit guide du ciel

    CERN Document Server

    Pellequer, Bernard

    2014-01-01

    Pour partir à la découverte du ciel nocturne, un petit guide simple, sûr et complet. Le tour du ciel en 32 cartes, pour apprendre à reconnaître les étoiles, mais d'abord à les observer - avec le meilleur des instruments : l'oeil. Des conseils pratiques d'observation, des cartes imprimées avec une encre fluorescente, les constellations visibles des deux hémisphères, Nord et Sud - de quoi mettre le ciel dans sa poche.

  19. La fabrique du droit.

    Directory of Open Access Journals (Sweden)

    Bénédicte Goussault

    2003-03-01

    Full Text Available Avec La fabrique du droit, Bruno Latour poursuit son anthropologie du monde moderne dont il écrit que la tâche consiste « à décrire de la même manière comment s'organisent toutes les branches de notre gouvernement, y compris celle de la nature et des sciences exactes, et d'expliquer comment et pourquoi ces branches se séparent, ainsi que les multiples arrangements qui les rassemblent » (Latour, 1991, p. 25 L'auteur, ethnologue ignorant de la chose, accompagne le ...

  20. Cartographie numérique en géologie de surface. Application aux altérites à silex de l'Ouest du bassin de Paris

    OpenAIRE

    Quesnel , Florence

    1997-01-01

    Thèse publiée. Document du BRGM, 263, 268 p et 160 p d'annexes.; The compilation of data from 50 geological maps (1:50,000 scale), 2,500 boreholes and their combination in the creation of thematic maps using G.I.S. software, has enabled the anatomy of the flint alterites (termed RS, residu à silex or "clay-with-flints") of the western Paris Basin to be established. Geostatistical treatment of the thickness variable of superficial plateau formations (RS + plateau loams + Cenozoic residuals) an...

  1. les cahiers du cread

    African Journals Online (AJOL)

    Our Journal “les cahiers du cread” is a quarterly economic review publishing original findings of empirical research and theoretical debates on fields pertaining to our mission coverage (Macro Economics, Industrial Economics and Firms, Human Development & Social Economics, Agriculture & Environment). Other websites ...

  2. Digital Story-Based Problem Solving Applications: Preservice Primary Teachers' Experiences and Future Integration Plans

    Science.gov (United States)

    Kilic, Çigdem; Sancar-Tokmak, Hatice

    2017-01-01

    This case study investigates how preservice primary school teachers describe their experiences with digital story-based problem solving applications and their plans for the future integration of this technology into their teaching. Totally 113 preservice primary school teachers participated in the study. Data collection tools included a…

  3. Renforcement des capacités du comité économique de l'Assemblée ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Promotion de la recherche sur l'entrepreneuriat en Asie du Sud-Est - application du Global Entrepreneurship Monitor. L'entrepreneuriat a été un facteur déterminant de la croissance et de la création d'emplois en Asie du Sud-Est. Voir davantagePromotion de la recherche sur l'entrepreneuriat en Asie du Sud-Est ...

  4. Systems Thinking for Life Cycle Sustainability Assessment: A Review of Recent Developments, Applications, and Future Perspectives

    Directory of Open Access Journals (Sweden)

    Nuri Cihat Onat

    2017-04-01

    Full Text Available Tracking the environmental impacts of production, use, and disposal of products (e.g., goods, and services have been an important issue in the global economy. Although Life Cycle Assessment (LCA is a widely applied method to track these environmental impacts and support policies, it has certain limitations and an isolated way of evaluating the environmental impacts with no consideration of social and economic impacts and mechanisms. To overcome the limits of current LCA, three mechanisms have been proposed in the literature: (1 broadening the indicators by including social and economic indicators in addition to the environmental impacts; (2 broadening the scope of analysis from product-level assessment to national and global levels; (3 deepening the assessment by inclusion of more mechanisms to account for interrelations among the system elements, uncertainty analysis, stakeholder involvement, etc. With these developments, LCA has been evolving into a new framework called Life Cycle Sustainability Assessment (LCSA. Practical application of LCSA requires integration of various methods, tools, and disciplines. In this study, a comprehensive literature review is conducted to investigate recent developments, current challenges, and future perspectives in the LCSA literature. According to the review, a high number (40% of LCSA studies are from the environmental science discipline, while contributions from other disciplines such as economics (3% and social sciences (9% are very low. On broadening the scope of analysis, 58% of the studies are product-level works, while 37% quantified the impacts at national level and achieved an economy-wide analysis, and only 5% of the studies were able to quantify the global impacts of products using LCSA framework. Furthermore, current applications of LCSA have not considered the rebound effects, feedback mechanisms, and interrelations of the system of interest sufficiently. To address these challenges, we present a

  5. Advanced thermal-hydraulic and neutronic codes: current and future applications. Summary and conclusions

    International Nuclear Information System (INIS)

    2001-05-01

    An OECD Workshop on Advanced Thermal-Hydraulic and Neutronic Codes Applications was held from 10 to 13 April 2000, in Barcelona, Spain, sponsored by the Committee on the Safety of Nuclear Installations (CSNI) of the OECD Nuclear Energy Agency (NEA). It was organised in collaboration with the Spanish Nuclear Safety Council (CSN) and hosted by CSN and the Polytechnic University of Catalonia (UPC) in collaboration with the Spanish Electricity Association (UNESA). The objectives of the Workshop were to review the developments since the previous CSNI Workshop held in Annapolis [NEA/CSNI/ R(97)4; NUREG/CP-0159], to analyse the present status of maturity and remnant needs of thermal-hydraulic (TH) and neutronic system codes and methods, and finally to evaluate the role of these tools in the evolving regulatory environment. The Technical Sessions and Discussion Sessions covered the following topics: - Regulatory requirements for Best-Estimate (BE) code assessment; - Application of TH and neutronic codes for current safety issues; - Uncertainty analysis; - Needs for integral plant transient and accident analysis; - Simulators and fast running codes; - Advances in next generation TH and neutronic codes; - Future trends in physical modeling; - Long term plans for development of advanced codes. The focus of the Workshop was on system codes. An incursion was made, however, in the new field of applying Computational Fluid Dynamic (CFD) codes to nuclear safety analysis. As a general conclusion, the Barcelona Workshop can be considered representative of the progress towards the targets marked at Annapolis almost four years ago. The Annapolis Workshop had identified areas where further development and specific improvements were needed, among them: multi-field models, transport of interfacial area, 2D and 3D thermal-hydraulics, 3-D neutronics consistent with level of details of thermal-hydraulics. Recommendations issued at Annapolis included: developing small pilot/test codes for

  6. Proceedings of the workshop on advanced thermal-hydraulic and neutronic codes: current and future applications

    International Nuclear Information System (INIS)

    2001-01-01

    An OECD Workshop on Advanced Thermal-Hydraulic and Neutronic Codes Applications was held from 10 to 13 April 2000, in Barcelona, Spain, sponsored by the Committee on the Safety of Nuclear Installations (CSNI) of the OECD Nuclear Energy Agency (NEA). It was organised in collaboration with the Spanish Nuclear Safety Council (CSN) and hosted by CSN and the Polytechnic University of Catalonia (UPC) in collaboration with the Spanish Electricity Association (UNESA). The objectives of the Workshop were to review the developments since the previous CSNI Workshop held in Annapolis [NEA/CSNI/ R(97)4; NUREG/CP-0159], to analyse the present status of maturity and remnant needs of thermal-hydraulic (TH) and neutronic system codes and methods, and finally to evaluate the role of these tools in the evolving regulatory environment. The Technical Sessions and Discussion Sessions covered the following topics: - Regulatory requirements for Best-Estimate (BE) code assessment; - Application of TH and neutronic codes for current safety issues; - Uncertainty analysis; - Needs for integral plant transient and accident analysis; - Simulators and fast running codes; - Advances in next generation TH and neutronic codes; - Future trends in physical modeling; - Long term plans for development of advanced codes. The focus of the Workshop was on system codes. An incursion was made, however, in the new field of applying Computational Fluid Dynamic (CFD) codes to nuclear safety analysis. As a general conclusion, the Barcelona Workshop can be considered representative of the progress towards the targets marked at Annapolis almost four years ago. The Annapolis Workshop had identified areas where further development and specific improvements were needed, among them: multi-field models, transport of interfacial area, 2D and 3D thermal-hydraulics, 3-D neutronics consistent with level of details of thermal-hydraulics. Recommendations issued at Annapolis included: developing small pilot/test codes for

  7. Virtual reality training in neurosurgery: Review of current status and future applications

    Science.gov (United States)

    Alaraj, Ali; Lemole, Michael G.; Finkle, Joshua H.; Yudkowsky, Rachel; Wallace, Adam; Luciano, Cristian; Banerjee, P. Pat; Rizzi, Silvio H.; Charbel, Fady T.

    2011-01-01

    Background: Over years, surgical training is changing and years of tradition are being challenged by legal and ethical concerns for patient safety, work hour restrictions, and the cost of operating room time. Surgical simulation and skill training offer an opportunity to teach and practice advanced techniques before attempting them on patients. Simulation training can be as straightforward as using real instruments and video equipment to manipulate simulated “tissue” in a box trainer. More advanced virtual reality (VR) simulators are now available and ready for widespread use. Early systems have demonstrated their effectiveness and discriminative ability. Newer systems enable the development of comprehensive curricula and full procedural simulations. Methods: A PubMed review of the literature was performed for the MESH words “Virtual reality, “Augmented Reality”, “Simulation”, “Training”, and “Neurosurgery”. Relevant articles were retrieved and reviewed. A review of the literature was performed for the history, current status of VR simulation in neurosurgery. Results: Surgical organizations are calling for methods to ensure the maintenance of skills, advance surgical training, and credential surgeons as technically competent. The number of published literature discussing the application of VR simulation in neurosurgery training has evolved over the last decade from data visualization, including stereoscopic evaluation to more complex augmented reality models. With the revolution of computational analysis abilities, fully immersive VR models are currently available in neurosurgery training. Ventriculostomy catheters insertion, endoscopic and endovascular simulations are used in neurosurgical residency training centers across the world. Recent studies have shown the coloration of proficiency with those simulators and levels of experience in the real world. Conclusion: Fully immersive technology is starting to be applied to the practice of

  8. Nuclear medicine imaging in clinical practice: Current applications and future trends

    International Nuclear Information System (INIS)

    Galli, G.; Maini, C.L.

    1985-01-01

    The following conclusions can be drawn: 1) Even though developments in data digitalization enable also other imaging techniques to extract functional information, it is likely that nuclear medicine will keep and possibly increase its key role for functional studies requiring quantitative data analyses. This statement is true at present and it will probably remain true for a long time to come. 2) Nuclear medicine is and will remain an important clinical tool also for morphological or morphodynamic studies in selected situations. Of course the integration of nuclear medicine studies with other diagnostic procedures is highly desirable. The highest clinical yield of multi-test diagnostic protocols will be anyway obtained by the wisest physician as sophysticated technology is no substitution for intelligent clinical judgment. 3) The development of new radiopharmaceuticals with well characterized biokinetic features allowing precise tissue characterization opens new frontiers to be exploited by nuclear medicine centers equipped with conventional technology (digital gammacameras, SPECT). 4) Positron emission tomography is the most important new development of nuclear medicine imaging. Not only PET has already shown its enormous possibilities for physiological and pathophysiological studies, but the clinical relevance of selected applications has been proved. More experience is however needed to assess systematically the whole impact of PET studies in clinical practice and to perform dependable cost/benefit studies. 5) Among all other imaging techniques NMR is the closest to nuclear medicine because of a strict ''compatibility of aptitudes, training and methodology'' (4). Accordingly future improvements of both methods will be better achieved if they could be integrated and the results compared with the same institutions

  9. Subscale Winged Rocket Development and Application to Future Reusable Space Transportation

    Directory of Open Access Journals (Sweden)

    Koichi YONEMOTO

    2018-03-01

    Full Text Available Kyushu Institute of Technology has been studying unmanned suborbital winged rocket called WIRES (WInged REusable Sounding rocket and its research subjects concerning aerodynamics, NGC (Navigation, Guidance and Control, cryogenic composite tanks etc., and conducting flight demonstration of small winged rocket since 2005. WIRES employs the original aerodynamic shape of HIMES (HIghly Maneuverable Experimental Sounding rocket studied by ISAS (Institute of Space and Astronautical Science of JAXA (Japan Aerospace Exploration Agency in 1980s. This paper presents the preliminary design of subscale non-winged and winged rockets called WIRES#013 and WIRES#015, respectively, that are developed in collaboration with JAXA, USC (University of Southern California, UTEP (University of Texas at El Paso and Japanese industries. WIRES#013 is a conventional pre-test rocket propelled by two IPA-LOX (Isopropyl Alcohol and Liquid Oxygen engines under development by USC. It has the total length of 4.6m, and the weight of 1000kg to reach the altitude of about 6km. The flight objective is validation of the telemetry and ground communication system, recovery parachute system, and launch operation of liquid engine. WIRES#015, which has the same length of WIRES#013 and the weight of 1000kg, is a NGC technology demonstrator propelled by a fully expander-cycle LOX-Methane engine designed and developed by JAXA to reach the altitude more than 6km. The flight tests of both WIRES#013 and WIRES#015 will be conducted at the launch facility of FAR (Friends of Amateur Rocketry, Inc., which is located at Mojave Desert of California in United States of America, in May 2018 and March 2019 respectively. After completion of WIRES#015 flight tests, the suborbital demonstrator called WIRES-X will be developed and its first flight test well be performed in 2020. Its application to future fully reusable space transportation systems, such as suborbital space tour vehicles and two

  10. New design of cable-in-conduit conductor for application in future fusion reactors

    Science.gov (United States)

    Qin, Jinggang; Wu, Yu; Li, Jiangang; Liu, Fang; Dai, Chao; Shi, Yi; Liu, Huajun; Mao, Zhehua; Nijhuis, Arend; Zhou, Chao; Yagotintsev, Konstantin A.; Lubkemann, Ruben; Anvar, V. A.; Devred, Arnaud

    2017-11-01

    The China Fusion Engineering Test Reactor (CFETR) is a new tokamak device whose magnet system includes toroidal field, central solenoid (CS) and poloidal field coils. The main goal is to build a fusion engineering tokamak reactor with about 1 GW fusion power and self-sufficiency by blanket. In order to reach this high performance, the magnet field target is 15 T. However, the huge electromagnetic load caused by high field and current is a threat for conductor degradation under cycling. The conductor with a short-twist-pitch (STP) design has large stiffness, which enables a significant performance improvement in view of load and thermal cycling. But the conductor with STP design has a remarkable disadvantage: it can easily cause severe strand indentation during cabling. The indentation can reduce the strand performance, especially under high load cycling. In order to overcome this disadvantage, a new design is proposed. The main characteristic of this new design is an updated layout in the triplet. The triplet is made of two Nb3Sn strands and one soft copper strand. The twist pitch of the two Nb3Sn strands is large and cabled first. The copper strand is then wound around the two superconducting strands (CWS) with a shorter twist pitch. The following cable stages layout and twist pitches are similar to the ITER CS conductor with STP design. One short conductor sample with a similar scale to the ITER CS was manufactured and tested with the Twente Cable Press to investigate the mechanical properties, AC loss and internal inspection by destructive examination. The results are compared to the STP conductor (ITER CS and CFETR CSMC) tests. The results show that the new conductor design has similar stiffness, but much lower strand indentation than the STP design. The new design shows potential for application in future fusion reactors.

  11. Engineered skeletal muscle tissue for soft robotics: fabrication strategies, current applications, and future challenges.

    Science.gov (United States)

    Duffy, Rebecca M; Feinberg, Adam W

    2014-01-01

    Skeletal muscle is a scalable actuator system used throughout nature from the millimeter to meter length scales and over a wide range of frequencies and force regimes. This adaptability has spurred interest in using engineered skeletal muscle to power soft robotics devices and in biotechnology and medical applications. However, the challenges to doing this are similar to those facing the tissue engineering and regenerative medicine fields; specifically, how do we translate our understanding of myogenesis in vivo to the engineering of muscle constructs in vitro to achieve functional integration with devices. To do this researchers are developing a number of ways to engineer the cellular microenvironment to guide skeletal muscle tissue formation. This includes understanding the role of substrate stiffness and the mechanical environment, engineering the spatial organization of biochemical and physical cues to guide muscle alignment, and developing bioreactors for mechanical and electrical conditioning. Examples of engineered skeletal muscle that can potentially be used in soft robotics include 2D cantilever-based skeletal muscle actuators and 3D skeletal muscle tissues engineered using scaffolds or directed self-organization. Integration into devices has led to basic muscle-powered devices such as grippers and pumps as well as more sophisticated muscle-powered soft robots that walk and swim. Looking forward, current, and future challenges include identifying the best source of muscle precursor cells to expand and differentiate into myotubes, replacing cardiomyocytes with skeletal muscle tissue as the bio-actuator of choice for soft robots, and vascularization and innervation to enable control and nourishment of larger muscle tissue constructs. © 2013 Wiley Periodicals, Inc.

  12. Virtual reality training in neurosurgery: Review of current status and future applications.

    Science.gov (United States)

    Alaraj, Ali; Lemole, Michael G; Finkle, Joshua H; Yudkowsky, Rachel; Wallace, Adam; Luciano, Cristian; Banerjee, P Pat; Rizzi, Silvio H; Charbel, Fady T

    2011-01-01

    Over years, surgical training is changing and years of tradition are being challenged by legal and ethical concerns for patient safety, work hour restrictions, and the cost of operating room time. Surgical simulation and skill training offer an opportunity to teach and practice advanced techniques before attempting them on patients. Simulation training can be as straightforward as using real instruments and video equipment to manipulate simulated "tissue" in a box trainer. More advanced virtual reality (VR) simulators are now available and ready for widespread use. Early systems have demonstrated their effectiveness and discriminative ability. Newer systems enable the development of comprehensive curricula and full procedural simulations. A PubMed review of the literature was performed for the MESH words "Virtual reality, "Augmented Reality", "Simulation", "Training", and "Neurosurgery". Relevant articles were retrieved and reviewed. A review of the literature was performed for the history, current status of VR simulation in neurosurgery. Surgical organizations are calling for methods to ensure the maintenance of skills, advance surgical training, and credential surgeons as technically competent. The number of published literature discussing the application of VR simulation in neurosurgery training has evolved over the last decade from data visualization, including stereoscopic evaluation to more complex augmented reality models. With the revolution of computational analysis abilities, fully immersive VR models are currently available in neurosurgery training. Ventriculostomy catheters insertion, endoscopic and endovascular simulations are used in neurosurgical residency training centers across the world. Recent studies have shown the coloration of proficiency with those simulators and levels of experience in the real world. Fully immersive technology is starting to be applied to the practice of neurosurgery. In the near future, detailed VR neurosurgical modules

  13. Investigations of binary and ternary phase change alloys for future memory applications

    International Nuclear Information System (INIS)

    Rausch, Pascal

    2012-01-01

    The understanding of phase change materials is of great importance because it enables us to predict properties and tailor alloys which might be even better suitable to tackle challenges of future memory applications. Within this thesis two topics have been approached: on the one hand the understanding of the alloy In 3 Sb 1 Te 2 and on the other hand the so called resistivity drift of amorphous Ge-Sn-Te phase change materials. The main topic covers an in depth discussion of the ternary alloy In 3 Sb 1 Te 2 . At first glance, this alloy does not fit into the established concepts of phase alloys: e.g. the existence of resonant bonding in the crystalline phase is not obvious and the number of p-electrons is very low compared to other phase change alloys. Furthermore amorphous phase change alloys with high indium content are usually not discussed in literature, an exception being the recent work by Spreafico et al. on InGeTe 2 . For the first time a complete description of In 3 Sb 1 Te 2 alloy is given in this work for the crystalline phase, amorphous phase and crystallization process. In addition comparisons are drawn to typical phase change materials like Ge 2 Sb 2 Te 5 /GeTe or prototype systems like AgInTe 2 and InTe. The second topic of this thesis deals with the issue of resistivity drift, i.e. the increase of resistivity of amorphous phase change alloys with aging. This drift effect greatly hampers the introduction of multilevel phase change memory devices into the market. Recently a systematic decrease of drift coefficient with stoichiometry has been observed in our group going from GeTe over Ge 3 Sn 1 Te 4 to Ge 2 Sn 2 Te 4 . These alloys are investigated with respect to constraint theory.

  14. Univariate time series modeling and an application to future claims amount in SOCSO's invalidity pension scheme

    Science.gov (United States)

    Chek, Mohd Zaki Awang; Ahmad, Abu Bakar; Ridzwan, Ahmad Nur Azam Ahmad; Jelas, Imran Md.; Jamal, Nur Faezah; Ismail, Isma Liana; Zulkifli, Faiz; Noor, Syamsul Ikram Mohd

    2012-09-01

    The main objective of this study is to forecast the future claims amount of Invalidity Pension Scheme (IPS). All data were derived from SOCSO annual reports from year 1972 - 2010. These claims consist of all claims amount from 7 benefits offered by SOCSO such as Invalidity Pension, Invalidity Grant, Survivors Pension, Constant Attendance Allowance, Rehabilitation, Funeral and Education. Prediction of future claims of Invalidity Pension Scheme will be made using Univariate Forecasting Models to predict the future claims among workforce in Malaysia.

  15. Caractéristiques morphologiques et optiques du silicium ...

    African Journals Online (AJOL)

    L'anodisation du silicium dans des solutions d'acide hydrofluorique HF est une méthode acquise dans la préparation du silicium poreux avec des applications potentielles dans les domaines tels l'électronique, l'optique ainsi que la technologie chimique et celle des capteurs de gaz et des biocapteurs. Le contrôle de la ...

  16. Caractéristiques morphologiques et optiques du silicium ...

    African Journals Online (AJOL)

    L'anodisation du silicium dans des solutions d'acide hydrofluorique HF est une méthode acquise dans la préparation du silicium poreux avec des applications potentielles dans les domaines tels l'électronique, l'optique ainsi que la technologie chimique et celle des capteurs de gaz et des biocapteurs. Le contrôle de la.

  17. Using Digital Technologies in Clinical HIV Research: Real-World Applications and Considerations for Future Work.

    Science.gov (United States)

    Andriesen, Jessica; Bull, Sheana; Dietrich, Janan; Haberer, Jessica E; Van Der Pol, Barbara; Voronin, Yegor; Wall, Kristin M; Whalen, Christopher; Priddy, Frances

    2017-07-31

    Digital technologies, especially if used in novel ways, provide a number of potential advantages to clinical research in trials related to human immunodeficiency virus (HIV) and acquired immune deficiency syndrome (AIDS) and may greatly facilitate operations as well as data collection and analysis. These technologies may even allow answering questions that are not answerable with older technologies. However, they come with a variety of potential concerns for both the participants and the trial sponsors. The exact challenges and means for alleviation depend on the technology and on the population in which it is deployed, and the rapidly changing landscape of digital technologies presents a challenge for creating future-proof guidelines for technology application. The aim of this study was to identify and summarize some common themes that are frequently encountered by researchers in this context and highlight those that should be carefully considered before making a decision to include these technologies in their research. In April 2016, the Global HIV Vaccine Enterprise surveyed the field for research groups with recent experience in novel applications of digital technologies in HIV clinical research and convened these groups for a 1-day meeting. Real-world uses of various technologies were presented and discussed by 46 attendees, most of whom were researchers involved in the design and conduct of clinical trials of biomedical HIV prevention and treatment approaches. After the meeting, a small group of organizers reviewed the presentations and feedback obtained during the meeting and categorized various lessons-learned to identify common themes. A group of 9 experts developed a draft summary of the findings that was circulated via email to all 46 attendees for review. Taking into account the feedback received, the group finalized the considerations that are presented here. Meeting presenters and attendees discussed the many successful applications of digital

  18. Comparaison du filtre adaptatif RIF et du filtre a base de reseau de ...

    African Journals Online (AJOL)

    Comparaison du filtre adaptatif RIF et du filtre a base de reseau de neurones pour le filtrage du courant de reference pour la commande du filtre actif parallele. C Benachaiba, A Bassou, B Mazari ...

  19. Droit du dommage corporel systèmes d'indemnisation

    CERN Document Server

    Lambert-Faivre, Yvonne

    2015-01-01

    Le Droit du dommage corporel est aujourd'hui une spécialité reconnue, à la convergence du droit civil et du droit pénal, du droit de la consommation et du droit de l'environnement, du droit de la sécurité sociale et du droit des transports, etc. La sécurité et l'intégrité de la personne humaine sont des droits fondamentaux où l'exigence éthique et l'équité confortent la règle juridique pour tenter d'indemniser les victimes de dommages corporels avec efficacité et transparence. Dans tous ces domaines, cette 8e édition rend compte de l'actualité du droit du dommage corporel : jurisprudence détaillée sur la nomenclature des préjudices réparables, à l'heure où sa consécration par décret reste en suspens, évaluation médicale et monétaire des préjudices, actualité jurisprudentielle du recours des tiers payeurs (article 25 de la loi du 21 décembre 2006 et ses difficultés d'application), sécurité sociale, responsabilité médicale et indemnisations des victimes d'accidents médica...

  20. Quantification statistique et étude expérimentale de mouvements sismiques : application à l'évaluation du risque

    OpenAIRE

    Caillot , Veronique

    1992-01-01

    Dans les réglementations parasismiques, les mouvements forts sont caractérisés par des spectres réglementaires adaptés aux conditions de site. Les formes spectrales ainsi spècifiées dans les règlements en vigueur de par le monde sont trés dispersées. Ce travail est donc une analyse critique et une réactualisalion des méthodes de caractérisation des mouvements forts pour l'évaluation de l'aléa sismique. Une étude préliminaire basée sur les données accélérométriques du réseau dense SMARTI (Taiw...

  1. Classification multisource via la théorie des fonctions de croyance : application à l'estimation du temps de parcours

    OpenAIRE

    BEN-AISSA, A; EL-FAOUZI, NE; LEFEVRE, E

    2009-01-01

    L'estimation du temps de parcours en présence de plusieurs sources de données hétérogènes est abordée comme un problème de fusion de classifieurs. Dans ce travail, la méthodologie de la fusion, opérée par la théorie des fonctions de croyance, est présentée et plusieurs solutions techniques sont abordées. Les résultats de ces différentes propositions sont illustrés dans le cadre de l'estimation des temps de parcours sur un réseau routier. Ces schémas montrent la propension de la fusion de clas...

  2. La mobilité quotidienne dans les grandes villes du monde : application de la théorie des réseaux bayésiens

    Directory of Open Access Journals (Sweden)

    Giovanni Fusco

    2004-02-01

    Full Text Available À la frontière entre statistiques multivariées et intelligence artificielle, les réseaux bayésiens sont un puissant outil de modélisation de connaissance systémique. Une utilisation particulièrement intéressante est celle de la recherche des liens causaux entre variables dans une base de données. Dans cet article, nous analysons une base de données urbaines sur la mobilité quotidienne couvrant plus de cent grandes villes mondiales. À l'aide d'algorithmes de génération de réseaux bayésiens, nous avons produit deux réseaux reliant les variables et traduisant deux hypothèses différentes sur la hiérarchie causale entre elles. Si l’on introduit l’hypothèse que la mobilité détermine la structure urbaine, on crée alors un réseau qui  identifie la motorisation de la population comme étant une variable cruciale. Ce réseau s’avère plus probable que celui résultant de l’hypothèse opposée. En revanche, les deux réseaux concordent sur l’importance de l’offre de voirie rapide urbaine et de la vitesse moyenne du réseau routier dans l’explication du partage modal et des coûts et des externalités des transports urbains.

  3. The TRIDEC Project: Future-Saving FOSS GIS Applications for Tsunami Early Warning

    Science.gov (United States)

    Loewe, P.; Wächter, J.; Hammitzsch, M.

    2011-12-01

    The Boxing Day Tsunami of 2004 killed over 240,000 people in 14 countries and inundated the affected shorelines with waves reaching heights up to 30m. This natural disaster coincided with an information catastrophy, as potentially life-saving early warning information existed, yet no means were available to deliver it to the communities under imminent threat. Tsunami Early Warning Capabilities have improved in the meantime by continuing development of modular Tsunami Early Warning Systems (TEWS). However, recent tsunami events, like the Chile 2010 and the Tohoku 2011 tsunami demonstrate that the key challenge for ongoing TEWS research on the supranational scale still lies in the timely issuing of reliable early warning messages. Since 2004, the GFZ German Research Centre for Geosciences has built up expertise in the field of TEWS. Within GFZ, the Centre for GeoInformation Technology (CEGIT) has focused its work on the geoinformatics aspects of TEWS in two projects already: The German Indonesian Tsunami Early Warning System (GITEWS) funded by the German Federal Ministry of Education and Research (BMBF) and the Distant Early Warning System (DEWS), a European project funded under the sixth Framework Programme (FP6). These developments are continued in the TRIDEC project (Collaborative, Complex, and Critical Decision Processes in Evolving Crises) funded under the European Union's seventh Framework Programme (FP7). This ongoing project focuses on real-time intelligent information management in Earth management and its long-term application. All TRIDEC developments are based on Free and Open Source Software (FOSS) components and industry standards where-ever possible. Tsunami Early Warning in TRIDEC is also based on mature system architecture models to ensure long-term usability and the flexibility to adapt to future generations of Tsunami sensors. All open source software produced by the project consortium are foreseen to be published on FOSSLAB, a publicly available

  4. Co-evolutionary scenarios: An application to prospecting futures of the responsible development of nanotechnology

    NARCIS (Netherlands)

    Robinson, D.K.R.

    2009-01-01

    Potentially breakthrough science and technologies promise applications which may radically affect society. Nanotechnology is no exception, promising many benefits through nano-enabled applications across multiple sectors and with the potential of affecting many parts of our society. At present,

  5. Investigations of binary and ternary phase change alloys for future memory applications

    Energy Technology Data Exchange (ETDEWEB)

    Rausch, Pascal

    2012-09-13

    The understanding of phase change materials is of great importance because it enables us to predict properties and tailor alloys which might be even better suitable to tackle challenges of future memory applications. Within this thesis two topics have been approached: on the one hand the understanding of the alloy In{sub 3}Sb{sub 1}Te{sub 2} and on the other hand the so called resistivity drift of amorphous Ge-Sn-Te phase change materials. The main topic covers an in depth discussion of the ternary alloy In{sub 3}Sb{sub 1}Te{sub 2}. At first glance, this alloy does not fit into the established concepts of phase alloys: e.g. the existence of resonant bonding in the crystalline phase is not obvious and the number of p-electrons is very low compared to other phase change alloys. Furthermore amorphous phase change alloys with high indium content are usually not discussed in literature, an exception being the recent work by Spreafico et al. on InGeTe{sub 2}. For the first time a complete description of In{sub 3}Sb{sub 1}Te{sub 2} alloy is given in this work for the crystalline phase, amorphous phase and crystallization process. In addition comparisons are drawn to typical phase change materials like Ge{sub 2}Sb{sub 2}Te{sub 5}/GeTe or prototype systems like AgInTe{sub 2} and InTe. The second topic of this thesis deals with the issue of resistivity drift, i.e. the increase of resistivity of amorphous phase change alloys with aging. This drift effect greatly hampers the introduction of multilevel phase change memory devices into the market. Recently a systematic decrease of drift coefficient with stoichiometry has been observed in our group going from GeTe over Ge{sub 3}Sn{sub 1}Te{sub 4} to Ge{sub 2}Sn{sub 2}Te{sub 4}. These alloys are investigated with respect to constraint theory.

  6. Prospects for the future development and application of the sterile insect technique

    International Nuclear Information System (INIS)

    Robinson, A.S.; Hendrichs, J.

    2005-01-01

    Science-based modern agriculture and international trade in agricultural commodities have achieved that, even though the world population has doubled in the last 40 years, the absolute number of people in poverty and hunger has been falling steadily. The major challenge in the immediate future is to consolidate these positive gains, while simultaneously expanding environment-friendly agricultural practices. Within this context, the sterile insect technique (SIT), as part of area-wide integrated pest management (AW-IPM) programmes, will continue to gain momentum for application against certain key insect pests. This is in response to the demands for cleaner food and a better environment, the need to facilitate increasing international trade by overcoming pest related trade barriers to the movement of agricultural commodities, and the imperative of dealing with the increasing invasion of exotic pests. As the use of the technology increases, changes will continue to be made to improve the overall efficiency of the technique for those species where the SIT is already being used, and to expand the use of the technique to new key species. Modem biotechnology may also contribute to improving efficiency and, even though there are as yet no transgenic strains of pest insects that could be used in AW-IPM programmes, transgenic technology may eventually benefit these programmes in terms of strain marking, genetic sexing, molecular sterilization, and disease refractoriness; however, first the regulatory hurdle to allow their use will have to be overcome. There appears to be much promise in improving sterile male performance by exposing male insects to hormonal, nutritional, microbial, and semiochemical supplements. Furthermore, the management of mother colonies will be significantly improved to reduce the effects of colonization and to slow down mass-rearing effects on key behavioural parameters that often result in rapid colony deterioration. Progress will also need to be

  7. La fin du risque zéro : du homegrown jihadism au terrorisme du loup solitaire

    Directory of Open Access Journals (Sweden)

    Rémi Baudouï

    2015-09-01

    Full Text Available Le risque zéro représente un moment historique particulier dans la conceptualisation de la socio-politique du risque. Son application repose au début des années 1980 sur l’hypothèse de la possibilité de progresser dans le domaine de l’anticipation et de la gestion sécuritaire des crises potentielles au point de pouvoir prémunir les populations contre toute forme de menace. Il fut employé dans les domaines de la protection civile et de la sécurité militaire. Comme élément de gouvernance politique, il réfutait l’idée selon laquelle le risque existe en préalable comme catégorie d’acceptabilité collective de la menace.

  8. Caracterisation du rajeunissement du noyer (Juglans sp.) pour une etude spectrophotometrique globale du contenu polyphenolique

    OpenAIRE

    Jay Allemand, Christian; Cornu, D.; Macheix, J.J.

    1987-01-01

    Cette étude a eu pour objet de rechercher des marqueurs biochimiques de la juvénilité chez le Noyer pour permettre d’apprécier l’état d’aptitude à la multiplication végétative des boutures et des microboutures avant et pendant l’application des traitements (température, lumière, milieux de culture...). A partir d’analyses spectrophotométriques effectuées sur des extraits purifiés de composés phénoliques de différentes catégories de pousses annuelles (selon l’âge du pied-mère, la taille, ...

  9. Aux origines du monde

    CERN Multimedia

    2004-01-01

    "C'est l'histoire d'une aventure humaine, scientifique, international qui a vu le jour il y a cinquante ans, aux confins de la Suisse et du département de l'Ain. Le plus grand laboratoire de physique des particules du monde, le Cern, a été fondé en 1954. Les festivités organisées à l occasion de cet anniversaire connaîtront leur point d'orgue le 16 octobre prochain, avec portes-ouvertes, accueil de personallités et inauguration d'un monumnet spécifique, le Globe de l'innovation" (2 pages)

  10. Le sens du portrait.

    Directory of Open Access Journals (Sweden)

    Christophe Apprill

    2007-01-01

    Full Text Available À l’entrée du vieux port de Marseille, le projet Euroméditerranée prévoit la construction d’un musée, le Musée des Civilisations de l’Europe et de la Méditerranée (M ucem . Il accueillera les anciennes collections du Musée National des Arts et Traditions Populaires (M natp que les badauds en promenade au jardin d’acclimatation croisaient sans le savoir. Un concours d’architecture a été lancé, remporté par un architecte de la région, Rudy Riccioti. Son projet ...

  11. CHOEUR DU CERN

    CERN Multimedia

    CHOEUR DU CERN

    2010-01-01

    Les répétitions du chœur du CERN reprendront le mercredi 15 septembre à 20.00 heures à l’amphithéâtre principal – bâtiment 500. Au programme la préparation de notre concert de Noël avec la Missa Brevis, KV115, de Léopold Mozart et de la musique de Noël d’Europe. Les personnes qui aiment chanter, notamment des sopranes et des ténors, sont les bienvenues. Pour tout contact s’adresser à : Baudouin Bleus - (tél.CERN 767 82 44) -(baudouin.bleus@cern.ch) ou Martin Gatehouse ( martin.gatehouse@wanadoo.fr) ou Jean-Paul Diss (jean-pauldiss@wanadoo.fr).  

  12. Portage vaginal du streptocoque du groupe B chez la femme ...

    African Journals Online (AJOL)

    Introduction: le streptocoque du groupe B est le principal agent impliqué dans les infections materno-fœtales, les septicémies et les méningites du nouveau-né à terme. L'objectif est de déterminer le taux de portage maternel du streptocoque du groupe B (SGB) à terme. Méthodes: un prélèvement vaginal a été réalisé de ...

  13. Afrique du Sud

    International Development Research Centre (IDRC) Digital Library (Canada)

    Cathy Egan

    fonction, en 1994, plus de la moitié des membres qui ont constitué le nouveau cabinet sud-africain avaient déjà participé à ... pour présenter une proposition de politique au Conseil des gouverneurs et, à l'automne de la même année, le Conseil approuvait des lignes directrices pour la programmation du CRDI en Afrique ...

  14. Cri du Chat syndrome

    OpenAIRE

    Cerruti Mainardi, Paola

    2006-01-01

    Abstract The Cri du Chat syndrome (CdCS) is a genetic disease resulting from a deletion of variable size occurring on the short arm of chromosome 5 (5p-). The incidence ranges from 1:15,000 to 1:50,000 live-born infants. The main clinical features are a high-pitched monochromatic cry, microcephaly, broad nasal bridge, epicanthal folds, micrognathia, abnormal dermatoglyphics, and severe psychomotor and mental retardation. Malformations, although not very frequent, may be present: cardiac, neur...

  15. Bulletin du CRDI #121

    International Development Research Centre (IDRC) Digital Library (Canada)

    Dans ce numéro, nous vous proposons des articles de CRDI.ca et nous vous invitons à visionner les faits saillants de notre participation à la Conférence de Montréal 2017. De plus, il reste encore du temps ... Demande de manifestations d'intérêt : renforcer la recherche et la formation en génie en Afrique Date butoir : le 24 ...

  16. Phytoextraction du cadmium, du cuivre, du plomb et du zinc par ...

    African Journals Online (AJOL)

    La phytorémediation est une technique alternative d'extraction des métaux lourds dans les sols contaminés. La capacité de Vetiveria nigritana à accumuler le cadmium (Cd), cuivre (Cu), plomb (Pb) et zinc (Zn) a été étudiée dans les sols ferrugineux tropicaux et les sols vertiques du Burkina Faso. L'étude a été conduite ...

  17. Hvad siger du, Oskar?

    DEFF Research Database (Denmark)

    Thurah, Thomas

    der Kong Ødipus, der stak sine øjne ud. Og Faust, der væddede med djævelen. Og Don Quixote og Huckleberry Finn og Dante og Candide. Og Romeo og Julie. Og en lille håndfuld til. Hvad siger du, Oskar? er en introduktion til tolv litterære hovedværker - i børnehøjde. Og så giver bogen sit eget bud på...

  18. Les Cahiers du CREAD

    African Journals Online (AJOL)

    Admin

    améliorer la réputation de Numericable-qui est en déficit. Accès du Numericable à des compétences marketing de SFR de mobile plus réactif, et agressif. Optimisation des dépenses marketing en unifiant toutes les offres autour de la seule marque SFR. L'offre quadruple play permet de fidéliser les clients des deux entités ...

  19. La mesure du danger

    CERN Document Server

    Manceron, Vanessa; Revet, Sandrine

    2014-01-01

    La mesure du danger permet d’explorer des dangers de nature aussi diverse que la délinquance, la pollution, l’écueil maritime, la maladie ou l’attaque sorcellaire, l’extinction d’espèces animales ou végétales, voire de la Planète tout entière. Au croisement de la sociologie, de l’anthropologie et de l’histoire, les différents articles analysent les pratiques concrètes de mesure pour tenter de comprendre ce qui se produit au cours de l’opération d’évaluation du danger sans préjuger de la nature de celui-ci. L’anthropologie a contribué à la réflexion sur l’infortune en s’intéressant aux temporalités de l’après : maladies, catastrophes, pandémies, etc. et en cherchant à rendre compte de l’expérience des victimes, de leur vie ordinaire bouleversée, de la recomposition du quotidien. Elle s’intéresse aussi aux autres types de mesures, les savoirs incorporés, qui reposent sur l’odorat, la vue ou le toucher et ceux qui ressortent d’une épistémologie « non ...

  20. Bilan du contrat Renco

    CERN Document Server

    Principe, R

    2005-01-01

    Durant les dernières années la section TS/CV-LHC a été concernée par un grand nombre de contrats de fourniture et installation pour le LHC. Aujourd’hui tous les principaux systèmes hydrauliques ont été rénovés et quelques deux cents kilomètres de nouvelle tuyauterie ont été installé dans le tunnel. Cette intense activité, comprenant l’installation d’un certain nombre de lignes cryogéniques, a augmentée l’expérience du groupe, tant du point de vue technique, que du point de vue de la gestion des situations complexes qui caractérisent un tel scénario. Cet article passe en revue un certain nombre de statistiques relatives au principal contrat de fourniture et installation de la tuyauterie pour LHC, le F467, de manière à en extraire un bilan utile à l’identification des possibles axes d’amélioration.

  1. Effets du charbon actif dans le milieu de culture sur l'induction de la ...

    African Journals Online (AJOL)

    SARAH

    30 avr. 2014 ... Conclusion et application de la recherche : L'ajout du charbon actif est bénéfique pour le développement .... développement du système racinaire et de ..... génotypes sélectionnés. Compte rendu. Premier séminaire maghrébin sur la génétique de la résistance du palmier dattier. Projet de lutte contre le.

  2. 86 Optimisation du dimensionnement des systèmes photovoltaïques ...

    African Journals Online (AJOL)

    REMI

    Introduction. Avec la montée du prix du pétrole, les centrales thermiques ne sont plus rentables et les énergies renouvelables deviennent des domaines d'étude privilégiés. Le rayonnement solaire fait partie de ces sources d'énergies remises récemment au goût du jour et dont les applications les plus récentes sont celles.

  3. Connaissances et usages traditionnels des plantes médicinales du ...

    African Journals Online (AJOL)

    Les plantes citées pourraient contenir pour la plupart des alcaloïdes, les tanins et les flavonoïdes. Conclusion et Application des résultats : La valorisation de ces plantes et la détermination du profil de santé des populations locales du département du Haut-Nyong nécessite la mise en place des unités de transformations ...

  4. Har du sikret din alderdom?

    DEFF Research Database (Denmark)

    Kiens, Bente; Aagaard, Peter Gjerndrup

    2006-01-01

    Daglig fysisk aktivitet kan betragtes som indbetaling op din personlige helbredspension. Jo mere du sætter ind på kontoen, og jo oftere du gør det, jo større er sandsynligheden for, at du lever længere og får et sundere helbred. Og det er aldrig for sent at starte med indbetalingerne....

  5. The biokinetics of uranium migrating from embedded DU fragments

    International Nuclear Information System (INIS)

    Leggett, R.W.; Pellmar, T.C.

    2003-01-01

    Military uses of depleted uranium (DU) munitions have resulted in casualties with embedded DU fragments. Assessment of radiological or chemical health risks from these fragments requires a model relating urinary U to the rate of migration of U from the fragments, and its accumulation in systemic tissues. A detailed biokinetic model for U has been published by the International Commission on Radiological Protection (ICRP), but its applicability to U migrating from embedded DU fragments is uncertain. Recently, ) conducted a study at the Armed Forces Radiobiology Research Institute (AFRRI) on the redistribution and toxicology of U in rats with implanted DU pellets, simulating embedded fragments. This paper compares the biokinetic data from that study with the behavior of commonly studied forms of U in rats (e.g., intravenously injected U nitrate). The comparisons indicate that the biokinetics of U migrating from embedded DU is similar to that of commonly studied forms of U with regard to long-term accumulation in kidneys, bone, and liver. The results provide limited support for the application of the ICRP's model to persons with embedded DU fragments. Additional information is needed with regard to the short-term behavior of migrating U and its accumulation in lymph nodes, brain, testicles, and other infrequently studied U repositories

  6. Future Talks,

    Directory of Open Access Journals (Sweden)

    Catherine Defeyt

    2010-11-01

    Full Text Available La conservation des matériaux modernes et les difficultés qui la caractérisent étaient l’objet du colloque international Future Talks, organisé par Die Neue Sammlung, The International Design Museum, les 22 et 23 octobre 2009 à Munich. Conservateurs-restaurateurs spécialisés, représentants des  institutions muséales les plus prestigieuses d’Europe et d’outre-Atlantique ainsi que chercheurs en sciences appliquées y ont présenté leurs travaux et recherches. En matière de design, d’art moderne e...

  7. Learning about Cri du Chat Syndrome

    Science.gov (United States)

    Skip to main content Learning About Cri du Chat Enter Search Term(s): Español Research Funding An Overview ... An NHGRI fact sheet Learning About Cri du Chat Syndrome What is cri du chat syndrome? What ...

  8. Tourisme et communautés rurales au Venezuela : vers une application des principes du Développement Durable

    Directory of Open Access Journals (Sweden)

    Olivier Dehoorne

    2008-02-01

    Full Text Available L’évolution récente du tourisme international au Venezuela est particulièrement intéressante : l'activité touristique qui reste très largement concentrée sur la côte caribéenne, et notamment l’île de Margarita, se diversifie au profit de nouveaux centres d’intérêt dans les régions intérieures. L’affichage de nouvelles volontés politiques sur la scène régionale et internationale, sous l’impulsion du président Chavez, a perturbé le marché touristique national qui était dominé pour les clientèles nord-américaines ; le Venezuela apparaît désormais aux yeux des Etats-Unis comme un pays à risque, instable. C’est dans ce contexte que s’inscrit le « Programa Andes Tropicales » [PAT] qui soutient le  développement rural dans les parcs nationaux ; ce programme repose sur la participation des populations locales et leur implication dans les politiques de conservation des ressources naturelles et culturelles sources de revenus. Le soutien financier des microprojets familiaux et communautaires doivent permettent de lutter contre la pauvreté.The recent evolution of international tourism in Venezuela is particularly interesting. Even if tourism activity remains heavily concentrated on the Caribbean coast, in particular on the island of Margarita, it is nevertheless diversifying gradually to make way for new areas of interest in the country’s interior. The display of new political will on the regional and international scene, under the leadership of President Chavez, has disrupted the national tourism market which was dominated by North American customers. Venezuela now appears in the eyes of the United States as a country that is at risk,and therefore unstable. It is in this context that the “Programa Andes Tropicales" [PAT] was developed to promote rural development in national parks; This program is based on the participation and involvement of local populations in the development of appropriate

  9. Etude par résonance paramagnétique électronique et activation neutronique du comportement d'ions lanthanides dans la fluorine : application à l'étude géochimique des filons de Montroc et du Burc (Tarn)

    OpenAIRE

    Meary, Alain

    1983-01-01

    Comprend : Bulletin du Bureau de recherches géologiques et minières. Section 2, Géologie des gîtes minéraux. - ; 4, 1982, p. 359-364 Mineralium deposita. - ; 17, 1982, p. 411-422; Dans le but de préciser les conditions, de formation des gisements de fluorine, des analyses de lanthanides ont été effectuées' dans une quarantaine d'échantillons provenant de coupes' transversales' de filons hydrothermaux de basse température (mines du Burc et de Montroc du district de l'Albigeois'dans le Tarn). D...

  10. Superconductivity Engineering and Its Application for Fusion 3.Superconducting Technology as a Gateway to Future Technology

    Science.gov (United States)

    Asano, Katsuhiko

    Hopes for achieving a new source of energy through nuclear fusion rest on the development of superconducting technology that is needed to make future equipments more energy efficient as well as increase their performance. Superconducting technology has made progress in a wide variety of fields, such as energy, life science, electronics, industrial use and environmental improvement. It enables the actualization of equipment that was unachievable with conventional technology, and will sustain future “IT-Based Quality Life Style”, “Sustainable Environmental” and “Advanced Healthcare” society. Besides coil technology with high magnetic field performance, superconducting electoronics or device technology, such as SQUID and SFQ-circuit, high temperature superconducting material and advanced cryogenics technology might be great significance in the history of nuclear fusion which requires so many wide, high and ultra technology. Superconducting technology seems to be the catalyst for a changing future society with nuclear fusion. As society changes, so will superconducting technology.

  11. Application and Development of Energy System Optimisation Models to Meet Challenges of the Future

    DEFF Research Database (Denmark)

    Balyk, Olexandr

    Climate change, security of supply and local air pollution are among the challenges that are shaping the future of energy systems worldwide. In response to these challenges, various goals are set nationally and internationally that energy systems are supposed to fulfil. These include e.g. EU 20...... them. The challenges of climate change, security of supply, and local air pollution are addressed in the papers by focusing on renewable energy systems, demand side management options, climate change mitigation and resource potentials. In the process of the study the energy system optimisation models...... upon in the Copenhagen Accord and the importance of large emerging economies in this context, and the role of district heating in the future Danish renewable energy system.The outcomes of this work illustrate the potential of energy system optimisation models to address challenges of the future...

  12. Where to from here? Future applications of mental models of complex performance

    International Nuclear Information System (INIS)

    Hahn, H.A.; Nelson, W.R.; Blackman, H.S.

    1988-01-01

    The purpose of this paper is to raise issues for discussion regarding the applications of mental models in the study of complex performance. Applications for training, expert systems and decision aids, job selection, workstation design, and other complex environments are considered. 1 ref

  13. Evaluating the future of HCI: challenges for the evaluation of emerging applications

    NARCIS (Netherlands)

    Poppe, Ronald Walter; Rienks, R.J.

    2007-01-01

    Current evaluation methods are inappropriate for emerging HCI applications. In this paper, we give three examples of these applications and show that traditional evaluation methods fail. We identify trends in HCI development and discuss the issues that arise with evaluation. We aim at achieving

  14. Evaluating the Future of HCI : Challenges for the Evaluation of Emerging Applications

    NARCIS (Netherlands)

    Poppe, Ronald Walter; Rienks, R.J.; van Dijk, Elisabeth M.A.G.; Huang, T.S; Nijholt, Antinus; Pantic, Maja; Pentland, A.

    2007-01-01

    Current evaluation methods are inappropriate for emerging HCI applications. In this paper, we give three examples of these applications and show that traditional evaluation methods fail. We identify trends in HCI development and discuss the issues that arise with evaluation. We aim at achieving

  15. Air Force Digital Technical Orders: Technologies and Applications for the Future

    Science.gov (United States)

    2002-12-01

    digital technical orders and assorted logistics applications in a field environment. The ability of electronic books (e-books), palm reader (e-reader...RESEARCH OBJECTIVE Determine if electronic books are a suitable document format for equipment manuals? Can they support weapon system... electronic books are a suitable document format for equipment manuals? IITA research has found that there are suitable software applications for

  16. Some applications of nanometer scale structures for current and future X-ray space research

    DEFF Research Database (Denmark)

    Christensen, Finn Erland; Abdali, S; Frederiksen, P K

    1994-01-01

    Nanometer scale structures such as multilayers, gratings and natural crystals are playing an increasing role in spectroscopic applications for X-ray astrophysics. A few examples are briefly described as an introduction to current and planned applications pursued at the Danish Space Research Insti...

  17. EFFET DU TUNGSTÈNE 0-8wt. % SUR LA MICROSTRUCTURE DES ALLIAGES Co-Cr UTILISES DANS DES APPLICATIONS ODONTOLOGIQUES

    Directory of Open Access Journals (Sweden)

    A KARAALI

    2004-06-01

    Full Text Available Les éléments d’addition tels que : W, Mo, Mn …, jouent un rôle  important dans la préoxydation des alliages dentaires et par conséquent,  sur la qualité de la liaison céramique /métal. Cette étude porte sur l'effet de l’addition de tungstène sur l'état microstructural des alliages Co-Cr, avant le processus de céramisation. Ces alliages ont été obtenus par solidification dirigée. Leur caractérisation, au moyen essentiellement la microscopie électronique à transmission (MET et la diffraction des rayons X, montre que l’addition du tungstène jusqu'à 8 % en poids implique des transformations structurales, intimement liées au pourcentage de cet élément contenu dans l’alliage.

  18. A new generation of optical diagnostics for bladder cancer: technology, diagnostic accuracy, and future applications

    NARCIS (Netherlands)

    Cauberg, Evelyne C. C.; de Bruin, Daniël M.; Faber, Dirk J.; van Leeuwen, Ton G.; de La Rosette, Jean J. M. C. H.; de Reijke, Theo M.

    2009-01-01

    CONTEXT: New developments in optical diagnostics have a potential for less invasive and improved detection of bladder cancer. OBJECTIVE: To provide an overview of the technology and diagnostic yield of recently developed optical diagnostics for bladder cancer and to outline their potential future

  19. A Third Note on Ageing in a Library Circulation Model: Applications to Future Use and Relegation.

    Science.gov (United States)

    Burrell, Quentin L.

    1987-01-01

    Describes a circulation model for academic research libraries which uses the mixed Poisson model, incorporating ageing of library materials, to predict future use of monographs and to suggest weeding procedures based on frequency of circulation. Longitudinal studies are examined and statistical details are appended. (Author/LRW)

  20. NanoString, a novel digital color-coded barcode technology: current and future applications in molecular diagnostics.

    Science.gov (United States)

    Tsang, Hin-Fung; Xue, Vivian Weiwen; Koh, Su-Pin; Chiu, Ya-Ming; Ng, Lawrence Po-Wah; Wong, Sze-Chuen Cesar

    2017-01-01

    Formalin-fixed, paraffin-embedded (FFPE) tissue sample is a gold mine of resources for molecular diagnosis and retrospective clinical studies. Although molecular technologies have expanded the range of mutations identified in FFPE samples, the applications of existing technologies are limited by the low nucleic acids yield and poor extraction quality. As a result, the routine clinical applications of molecular diagnosis using FFPE samples has been associated with many practical challenges. NanoString technologies utilize a novel digital color-coded barcode technology based on direct multiplexed measurement of gene expression and offer high levels of precision and sensitivity. Each color-coded barcode is attached to a single target-specific probe corresponding to a single gene which can be individually counted without amplification. Therefore, NanoString is especially useful for measuring gene expression in degraded clinical specimens. Areas covered: This article describes the applications of NanoString technologies in molecular diagnostics and challenges associated with its applications and the future development. Expert commentary: Although NanoString technology is still in the early stages of clinical use, it is expected that NanoString-based cancer expression panels would play more important roles in the future in classifying cancer patients and in predicting the response to therapy for better personal therapeutic care.

  1. 'Maintain FENDL library for fusion applications'. FENDL-2 library for fusion applications - Status and future developments. Summary report

    International Nuclear Information System (INIS)

    Forrest, R.; Trkov, A.

    2003-11-01

    The discussions and conclusions of the meeting to 'Maintain FENDL library for Fusion Applications' are summarized in this report. A presentation was made by each of the participants, followed by a review of FENDL-2: evaluations and recommendations, and discussions on the special purpose libraries and processed files, with relevant further action thereon being determined. (author)

  2. Current Status and Future Research Opportunities for Electrochemical Capacitors: Relevance for Naval and Civilian Applications

    National Research Council Canada - National Science Library

    Long, Jeffrey W

    2008-01-01

    ... energy density of batteries. As such, ECs will ultimately enable technologies and applications, ranging from microelectronics to hybrid- and all-electric vehicle platforms, where current energy-storage devices are not sufficient...

  3. Evolving PBPK applications in regulatory risk assessment: current situation and future goals

    Science.gov (United States)

    The presentation includes current applications of PBPK modeling in regulatory risk assessment and discussions on conflicts between assuring consistency with experimental data in current situation and the desire for animal-free model development.

  4. AnnAGNPS Model Application for Nitrogen Loading Assessment for the Future Midwest Landscape Study

    Directory of Open Access Journals (Sweden)

    Michael A. Jackson

    2011-02-01

    Full Text Available The Future Midwest Landscape (FML project is part of the US Environmental Protection Agency (EPA’s new Ecosystem Services Research Program, undertaken to examine the variety of ways in which landscapes that include crop lands, conservation areas, wetlands, lakes, and streams affect human well-being. The goal of the FML project is to quantify current and future ecosystem services across the region and to examine changes expected to occur as a result of the growing demand for biofuels. This study is one of several pilots taking place under the umbrella of the FML research project. In this study, the USDA Annualized Agricultural Non-Point Source Pollution (AnnAGNPS model was applied to the East Fork Kaskaskia River watershed (289.3 km2 located in the Kaskaskia River Basin within the Upper Mississippi River Basin in Illinois. The effect of different spatial resolutions on model performance was investigated by comparing the observed runoff with the AnnAGNPS simulated results. Alternative future scenarios such as meeting future biofuel target were also simulated and analyzed. All delineations of the study area (coarser to finer produced satisfactory results in simulating monthly and annual runoff. However, the size of the delineation does impact the simulation results. Finer delineations better represented the actual landscape and captured small critical areas that would be homogenized in coarser delineation. Those small critical areas are important to target to achieve maximum environment benefit. Simulations of alternative future scenarios showed that as corn production increases to meet future biofuel needs, total nitrogen loss increases. For this watershed, total N loss would be more than doubled if converting all corn/soybean rotation (15,871.2 ha to continuous corn comparing with the base year total N loss which is 11.2 kg/ha. Conservation practices are needed to reduce total nitrogen loss from the watershed. This study provides an important

  5. Examples of Current and Future Uses of Neural-Net Image Processing for Aerospace Applications

    Science.gov (United States)

    Decker, Arthur J.

    2004-01-01

    Feed forward artificial neural networks are very convenient for performing correlated interpolation of pairs of complex noisy data sets as well as detecting small changes in image data. Image-to-image, image-to-variable and image-to-index applications have been tested at Glenn. Early demonstration applications are summarized including image-directed alignment of optics, tomography, flow-visualization control of wind-tunnel operations and structural-model-trained neural networks. A practical application is reviewed that employs neural-net detection of structural damage from interference fringe patterns. Both sensor-based and optics-only calibration procedures are available for this technique. These accomplishments have generated the knowledge necessary to suggest some other applications for NASA and Government programs. A tomography application is discussed to support Glenn's Icing Research tomography effort. The self-regularizing capability of a neural net is shown to predict the expected performance of the tomography geometry and to augment fast data processing. Other potential applications involve the quantum technologies. It may be possible to use a neural net as an image-to-image controller of an optical tweezers being used for diagnostics of isolated nano structures. The image-to-image transformation properties also offer the potential for simulating quantum computing. Computer resources are detailed for implementing the black box calibration features of the neural nets.

  6. La naissance du Purgatoire

    OpenAIRE

    Laura Mello e Souza

    1983-01-01

    Le Goff, Jacques. La naissance du Purgatoire. Paris, Gallimard, 1981, 509 p. (primeiro parágrafo do texto) Desde o período áureo dos Annales e dos escritos de Marc Bloch, Febvre e Braudel, responsáveis por novos rumos na historiografia con-temporânea, os anglo-saxões vêm empanando o brilho dos mestres france-ses . Hobsbawm e Thompson dedicaram estudos clássicos à sociedade pré-industrial e ao mundo da indústria nascente; Wallerstein e Perry Anderson repensaram o absolutismo e a consti...

  7. discours du Directeur General

    CERN Multimedia

    CERN. Geneva

    2007-01-01

    L'année 2007 est une année très spéciale pour le CERN. Je vous propose de nous retrouver pour faire le point sur les activités en cours. Rendez-vous le mercredi 27 juin à 15h00 dans l'amphithéâtre principal. La transmission simultanée sera assurée dans les amphithéâtres IT, AT, AB Prevessin et dans la Salle du Conseil. Robert Aymar

  8. Bulletin du CRDI #126

    International Development Research Centre (IDRC) Digital Library (Canada)

    26 févr. 2018 ... Dans ce numéro, découvrez comment la recherche financée par le CRDI permet d'améliorer la santé des mères et des enfants dans les pays du Sud et comment les innovations techniques et sociales de l'initiative SEARCH permettent de surmonter les défis liés à la cybersanté. N'oubliez pas non plus de ...

  9. Les Cahiers du CREAD

    African Journals Online (AJOL)

    Admin

    choix entre les options de gestion des déchets n'est pas aussi facile aise à hiérarchiser notamment lorsque les gouvernements cherchent à minimiser les coûts. 1.4. Hiérarchie des modes d'élimination de déchets. Idéalement, le choix stratégique du mode d'élimination des déchets devrait être fondé sur des estimations des ...

  10. Radiographie du lobbying en France

    OpenAIRE

    Courty, Guillaume

    2004-01-01

    Les résultats de l'enquête présentée ici proviennent des recherches coordonnées dans le séminaire de sociologie du lobbying du DESS de Droit de la vie politique de l'université Paris X Nanterre durant l'année 2003-2004.

  11. Cri-du-chat syndrome

    Directory of Open Access Journals (Sweden)

    Eka Agustia Rini

    2007-07-01

    there is no cure for cri-du-chat syndrome. The most successful approach in the management of children with CDCS requires a multidisciplinary team approach. 4 The case presented below will remind us how to reveal, suspect and diagnose Cri-Du-Chat syndrome, a rare case in pediatric.

  12. Archives: les cahiers du cread

    African Journals Online (AJOL)

    Items 1 - 24 of 24 ... Archives: les cahiers du cread. Journal Home > Archives: les cahiers du cread. Log in or Register to get access to full text downloads. Username, Password, Remember me, or Register · Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives. 1 - 24 of 24 Items. 2016 ...

  13. NASA advanced space photovoltaic technology-status, potential and future mission applications

    Science.gov (United States)

    Flood, Dennis J.; Piszczor, Michael, Jr.; Stella, Paul M.; Bennett, Gary L.

    1989-01-01

    The NASA program in space photovoltaic research and development encompasses a wide range of emerging options for future space power systems, and includes both cell and array technology development. The long range goals are to develop technology capable of achieving 300 W/kg for planar arrays, and 300 W/sq m for concentrator arrays. InP and GaAs planar and concentrator cell technologies are under investigation for their potential high efficiency and good radiation resistance. The Advanced Photovoltaic Solar Array (APSA) program is a near term effort aimed at demonstrating 130 W/kg beginning of life specific power using thin (62 micrometer) silicon cells. It is intended to be technology transparent to future high efficiency cells and provides the baseline for development of the 300 W/kg array.

  14. Basics of Compounding: 3D Printing: Pharmacy Applications, Part 3: Compounding, Formulation Considerations, and the Future.

    Science.gov (United States)

    Allen, Loyd V

    2017-01-01

    3D printing is a standard tool in the automotive, aerospace, and consumer goods in industry and is gaining traction in pharmaceutical manufacturing, which has introduced a new element into dosage form development. This article, which represents part 3 of a 3-part article on the topic of 3D printing, discusses the compounding, formulation considerations, and the future of 3D printing. Copyright© by International Journal of Pharmaceutical Compounding, Inc.

  15. Envisioning the future of aquatic animal tracking: Technology, science, and application

    DEFF Research Database (Denmark)

    Lennox, Robert J.; Aarestrup, Kim; Cooke, Steven J.

    2017-01-01

    Electronic tags are significantly improving our understanding of aquatic animal behavior and are emerging as key sources of information for conservation and management practices. Future aquatic integrative biology and ecology studies will increasingly rely on data from electronic tagging. Continued...... of animals and the environment through which they are moving. Improved data collection will be accompanied by greater data accessibility and analytical tools for processing data, enabled by new infrastructure and cyberinfrastructure. To operationalize advances and facilitate integration into policy...

  16. Applications de la résonance magnétique nucléaire (RMN en milieu poreux Lissage des courbes de relaxation RMN du domaine du temps par une méthode discrète et continue Nuclear Magnetic Resonance (Nmr Applications in Porous Media Time-Dependent Nmr Relaxation Curve Smoothing Using a Discrete Continuous Method

    Directory of Open Access Journals (Sweden)

    Le Botlan D.

    2006-12-01

    Full Text Available Dans un champ magnétique hétérogène, le signal RMN de précession libre (FID suit une évolution gaussienne. Le traitement du signal par une méthode discrète peut donner des composantes qui ne correspondent pas à un état physique réel. Par contre l'utilisation d'une méthode de déconvolution continue nous a donné des résultats quantitatifs tout à fait satisfaisants permettant de déterminer les distributions de temps de relaxation correspondant à des états intermédiaires entre les phases solides et liquides. La RMN du domaine du temps peut ainsi être considérée comme une méthode analytique complémentaire des techniques habituellement utilisées pour l'étude de composés complexes hétérogènes ATD, ACD, isothermes de sorption, etc. In a heterogeneous magnetic field, the freely precessing NMR signal (FID describes a Gaussian curve. Processing the signal using a discrete method can give rise to components that do not correspond to a real physical state. However, with a continuous deconvolution method, which gives quite satisfactory quantitative results, it is possible to determine the distributions of relaxation times that correspond to intermediate states between solid and liquid phases. Time-dependent NMR can thus be used to supplement the usual analytical methods, such as DTA, DCA and sorption isotherms, for studying complex heterogeneous compounds.

  17. Contribution à l'analyse et à l'interprétation du mouvement humain: application à la reconnaissance de postures

    OpenAIRE

    Girondel, Vincent

    2006-01-01

    This Ph.D. thesis research work is dedicated to the analysis and the interpretation of human motion with an application to posture recognition. Human motion analysis and interpretation in computer vision have numerous applications domains such as videosurveillance, mixed-reality applications and advanced man-machine interfaces. We propose here a real-time system that allows human motion analysis and interpretation.Human motion analysis includes several processing steps of image processing suc...

  18. Estimation of the Source Apportionment of Phosphorus and Its Responses to Future Climate Changes Using Multi-Model Applications

    Directory of Open Access Journals (Sweden)

    Jian Sha

    2018-04-01

    Full Text Available The eutrophication issue in the Yangtze Basin was considered, and the phosphorus loads from its tributary, the Modaoxi River, were estimated. The phosphorus flux and source apportionment of the Modaoxi River watershed were modeled and quantified, and their changes with respect to future projected climate scenarios were simulated with multiple model applications. The Regional Nutrient Management (ReNuMa model based on Generalized Watershed Loading Functions (GWLF was employed as a tool to model the hydrochemical processes of the watershed and thereby estimate the monthly streamflow and the phosphorus flux as well as its source apportionment. The Long Ashton Research Station Weather Generator (LARS-WG was used to predict future daily weather data through the statistical downscaling of the general circulation model (GCM outputs based on projected climate scenarios. The synthetic time series of daily precipitation and temperatures generated by LARS-WG were further used as input data for ReNuMa to estimate the responses of the watershed hydrochemical processes to future changed climate conditions. The results showed that both models could be successfully applied and that the future wetter and warmer climate trends would have generally positive impacts on the watershed phosphorus yields, with greater contributions coming from runoff. These results could provide valuable support for local water environmental management.

  19. Nuclear data for medical applications: An overview of present status and future needs

    Science.gov (United States)

    Syed, M. Qaim

    2017-09-01

    A brief overview of nuclear data required for medical applications is given. The major emphasis is on radionuclides for internal applications, both for diagnosis and therapy. The status of the presently available data is discussed and some of the emerging needs are outlined. Most of the needs are associated with the development of non-standard positron emitters and novel therapeutic radionuclides. Some new developments in application of radionuclides, e.g. theranostic approach, multimode imaging, radionanoparticles, etc. are described and the related nuclear data needs are discussed. The possible use of newer irradiation technologies for medical radionuclide production, e.g. intermediate energy charged-particle accelerators, high-power electron accelerators for photon production, and spallation neutron sources, will place heavy demands on nuclear data.

  20. Management of cyber physical objects in the future Internet of Things methods, architectures and applications

    CERN Document Server

    Loscri, Valeria; Rovella, Anna; Fortino, Giancarlo

    2016-01-01

    This book focuses on new methods, architectures, and applications for the management of Cyber Physical Objects (CPOs) in the context of the Internet of Things (IoT). It covers a wide range of topics related to CPOs, such as resource management, hardware platforms, communication and control, and control and estimation over networks. It also discusses decentralized, distributed, and cooperative optimization as well as effective discovery, management, and querying of CPOs. Other chapters outline the applications of control, real-time aspects, and software for CPOs and introduce readers to agent-oriented CPOs, communication support for CPOs, real-world deployment of CPOs, and CPOs in Complex Systems. There is a focus on the importance of application of IoT technologies for Smart Cities.

  1. Nuclear data for medical applications: An overview of present status and future needs

    Directory of Open Access Journals (Sweden)

    Syed M.Qaim

    2017-01-01

    Full Text Available A brief overview of nuclear data required for medical applications is given. The major emphasis is on radionuclides for internal applications, both for diagnosis and therapy. The status of the presently available data is discussed and some of the emerging needs are outlined. Most of the needs are associated with the development of non-standard positron emitters and novel therapeutic radionuclides. Some new developments in application of radionuclides, e.g. theranostic approach, multimode imaging, radionanoparticles, etc. are described and the related nuclear data needs are discussed. The possible use of newer irradiation technologies for medical radionuclide production, e.g. intermediate energy charged-particle accelerators, high-power electron accelerators for photon production, and spallation neutron sources, will place heavy demands on nuclear data.

  2. Advances in Silver Nanotechnology: An Update on Biomedical Applications and Future Perspectives.

    Science.gov (United States)

    Aziz, Shiva Gholizadeh-Ghaleh; Aziz, Sara Gholizadeh-Ghaleh; Akbarzadeh, Abolfazl

    2017-04-01

    Nanotechnology is one of the most promising fields for producing new applications in nanotechnology, biotechnology, and medicine. However, only a few products have been used for nanotechnology, biotechnology, and medical purposes. Nanoparticles have been among the most usually applied nanomaterial in our health care system for hundreds of years. The most prominent nano product is nano silver which generally present at 1-100 nm in size in at least one dimension. Silver nanoparticles reveal remarkably unusual chemical, physical and biological properties and have been used for many different applications which detailed in this review. This review is focusing on the different form of silver nanoparticles and its nanotechnological, biotechnological and medical applications. © Georg Thieme Verlag KG Stuttgart · New York.

  3. Present status and future prospects of industrial applications of isotopes in Bangladesh

    International Nuclear Information System (INIS)

    Ullah, M.D.S.

    1997-01-01

    Ionising radiation is used for quality assurance and quality control of many industrial products. Bangladesh is actively working on the industrial application of isotopes in the fields of non-destructive testing (NDT) of material, nuclear analytical technique, radiation technology, tracer technology through the participation in the UNDP/IAEA/RCA Project for Asia and the Pacific on the industrial application of isotopes and radiation technology. Bangladesh is developing NDT technology to such an extent and standard that the country is attaining self-reliance in this field for service and human resource development and the foreign dependence is becoming greatly reduced. Examples of recent achievements are given

  4. Present status and future prospects of industrial applications of isotopes in Bangladesh

    Energy Technology Data Exchange (ETDEWEB)

    Ullah, M.D.S. [Bangladesh Atomic Energy Commission, Ramna Dhaka (Bangladesh)

    1997-10-01

    Ionising radiation is used for quality assurance and quality control of many industrial products. Bangladesh is actively working on the industrial application of isotopes in the fields of non-destructive testing (NDT) of material, nuclear analytical technique, radiation technology, tracer technology through the participation in the UNDP/IAEA/RCA Project for Asia and the Pacific on the industrial application of isotopes and radiation technology. Bangladesh is developing NDT technology to such an extent and standard that the country is attaining self-reliance in this field for service and human resource development and the foreign dependence is becoming greatly reduced. Examples of recent achievements are given

  5. Les risques du travail

    CERN Document Server

    Thébaud-Mony, Annie

    2015-01-01

    Depuis les années 1990, les conditions de travail se sont peu à peu imposées dans le débat social. Néanmoins, la situation reste critique. Les risques traditionnels n'ont pas disparu : les manutentions lourdes, l'exposition professionnelle aux cancérogènes, au bruit ou aux vibrations demeurent répandues... De plus, certaines " améliorations " n'ont fait que déplacer et dissimuler les problèmes, telle l'externalisation des risques grâce à la sous-traitance. Dans le même temps, les transformations du travail et des modalités de gestion de la main-d'œuvre ont fragilisé les collectifs et accru l'isolement des salariés, conduisant à une montée visible de la souffrance psychique. Face à ces évolutions, il est plus que jamais nécessaire que tous les acteurs concernés, en particulier les salariés eux-mêmes et leurs représentants, s'approprient les connaissances indispensables pour améliorer la protection de la santé sur les lieux du travail. Tel est le but de ce livre, qui renouvelle int�...

  6. Les formes du fond

    Directory of Open Access Journals (Sweden)

    Michel Maffesoli

    2004-12-01

    Full Text Available Il n'est pas vrai que la nature a horreur du vide. Peut-être même s'y complait-elle. Le creux est aussi une modalité de l'être. Il est possible de s'y nicher, de s'y lover paresseusement et, ainsi, de se protéger contre l'angoisse du temps qui passe. Le creux des apparences est, à certains moments, une des formes d'expression de la vie sociale. Encore faut-il savoir le reconnaître. Certes, nous avons tous une existence personnelle, mais nous sommes, également, les représentants, parfois même les victimes, d'un "esprit commun", peut-être même d'un "inconscient collectif" qui s'est constitué de siècle en siècle. Et, très souvent, là où nous croyons exprimer nos propres idées, nous ne sommes que les porte-voix, les figurants d'un vaste "theatrum mundi" aux dimensions infinies.

  7. Choeur du CERN : Concert

    CERN Document Server

    CERN Choir

    2017-01-01

    Une œuvre à découvrir! La grande Missa pro defunctis de François-Joseph Gossec (1734-1829) est le chef-d’œuvre tôt venu (à vingt-cinq ans) d’un compositeur qui vivra encore 70 ans après sa création. Elle a connu la gloire, puis s’est fait un peu oublier. Pas du tout le monde cependant : des musicologues ont montré ce que le Requiem de Mozart lui devait ; et il suffit de l’avoir entendue pour comprendre pourquoi Berlioz (qui avait vingt-six ans à la mort de Gossec) en a été impressionné : les nombreux cuivres et bois répartis dans des endroits plus ou moins cachés de la salle de concert pour exprimer les frayeurs du Jugement dernier annoncent son Requiem – et celui de Verdi. Mais « plus encore que par...

  8. Harmful effects of DU in the offspring of the military personnel employed in DU contaminated regions

    International Nuclear Information System (INIS)

    Atlagic, N.; Lisov, Lj.; Barjaktarovic, V.; Djurovic, B.; Spasic, Jokic V.

    2008-01-01

    Full text: In 1999, during the NATO attacks on Kosovo, from AT-10 aircraft has been shot over 50000 30-mm projectiles which contained approximately 15 tones of DU. Besides DU, projectiles contained products of DU radioactive decay as well as americium, neptunium, plutonium and technetium. Due to DU contamination military personnel employed near hit targets could be contaminated and irradiated. Besides the harmful effects in exposed military personnel, harmful effects were noticed in their offsprings, too. DU can cause genetic and teratogenic harmful effects in the embryos/fetus. It is concentrated in semen of contaminated males and also can contaminate the embryo/fetus through placenta. DU, as a toxic and radioactive element, can cause variety of harmful effects, but the most important are the effects on DNA which are the cause of many diseases. The aim of this paper is to examine is there any change in the incidence in heritable effects, congenital malformations, malignant diseases, endocrine and immune disorders. For that reason we compared the incidence of these diseases in the offspring's of military personnel born from 1995-1999 (1204) with the children born from 2000-2004 (1131) / and 2005-2008. Our results showed higher incidence of congenital malformations and chromosomal abnormalities (12.55 % vs 4.57 %), with highest incidence of foot deformity-52.04 % and hip deformity. These abnormalities were followed with immunological disorders and dysfunction of the urine bladder. Endocrine diseases were increased too(2.16 % :1.63 %). In this period higher incidence of malignant diseases was not noticed, but in the second period (from 5-9 year) after 1999, higher incidence of malignant hematological diseases was noticed, as well as Down Sy. During the conflicts future parents as well as embryo/fetus are exposed to many harmfulness and it is very hard to separate the influence of each. Considering the fact that the effects of DU, could be delayed and synergistic with

  9. Radiation education for secondary school level in Asia-application of Japanese experiences and future mission

    International Nuclear Information System (INIS)

    Iimoto, Takeshi; Kakefu, Tomohisa; Takahashi, Itaru; Takaki, Rieko

    2015-01-01

    A mission on the development of nuclear science and technology education program for secondary school students in the Asia-Pacific Ocean area by the IAEA (2012 - 2015 years) is in progress. Attractive educational programs covering fields of science, technology, engineering and mathematics (STEM) have been developed. Selected pilot countries (the Philippines, Malaysia, Indonesia, UAE) use the programs and education tools as their trial under their own circumstances. Background and trends of this activity, Japanese support to the activity, and its future scope are introduced. (author)

  10. Current development and future perspectives of the application of radioisotopes and radiation in Japan

    International Nuclear Information System (INIS)

    Umezawa, H.

    1994-01-01

    Development of the use of radioisotopes and radiation is reviewed over the last thirty years based on the statistics on the distribution of radioisotopes and generators in Japan. The prosperity and decline of radioisotopes are discussed accompanying the technological and sociological environment of their use. There is a tendency to substitute non-radio technology for the use of radioisotope and radiation. Future perspectives are studied on the use of major radioisotopes. Status of the use of radiation generators is also described. 2 refs., 2 tabs., 7 figs

  11. Hydrogen as Future Energy Carrier: The ENEA Point of View on Technology and Application Prospects

    Directory of Open Access Journals (Sweden)

    Marina Ronchetti

    2009-03-01

    Full Text Available Hydrogen and fuel cells should reduce costs and increase reliability and durability to compete in the energy market. A considerable long term effort is necessary for research, development and demonstration of adequate solutions; important programs in this sense are carried out in the main industrialized countries, with the involvement of many industries, research structures and stakeholders. In such framework a relevant role is played in Italy by ENEA (Italian Agency for New Technologies, Energy and Environment. In the paper the main aspects related to the possible hydrogen role in the future society are addressed, according to ENEA perspectives.

  12. Agent Technology in Supply Chains and Networks: An exploration of high potential future applications

    NARCIS (Netherlands)

    van Hillegersberg, Jos; Verduijn, Thierry; Becker, Justus

    2004-01-01

    This paper reports on an ongoing research project that is aimed at evaluating how software agents can improve performance of supply chains and networks. To conduct this evaluation, first a framework is developed to classify potential applications of software agents to supply networks. The framework

  13. Village Stability Operations in Afghanistan: Comparing Past Counterinsurgencies for Future Applications

    Science.gov (United States)

    2013-12-13

    support, understanding, and patience provided me the time to conduct the necessary research and compose this thesis. I am grateful for her sacrifices and...in more money coming into the village. Common application of successful micro-grants can be found in chicken farming, animal husbandry, local

  14. Two-Dimensional Nanomaterials for Biomedical Applications: Emerging Trends and Future Prospects.

    Science.gov (United States)

    Chimene, David; Alge, Daniel L; Gaharwar, Akhilesh K

    2015-12-02

    Two-dimensional (2D) nanomaterials are ultrathin nanomaterials with a high degree of anisotropy and chemical functionality. Research on 2D nanomaterials is still in its infancy, with the majority of research focusing on elucidating unique material characteristics and few reports focusing on biomedical applications of 2D nanomaterials. Nevertheless, recent rapid advances in 2D nanomaterials have raised important and exciting questions about their interactions with biological moieties. 2D nanoparticles such as carbon-based 2D materials, silicate clays, transition metal dichalcogenides (TMDs), and transition metal oxides (TMOs) provide enhanced physical, chemical, and biological functionality owing to their uniform shapes, high surface-to-volume ratios, and surface charge. Here, we focus on state-of-the-art biomedical applications of 2D nanomaterials as well as recent developments that are shaping this emerging field. Specifically, we describe the unique characteristics that make 2D nanoparticles so valuable, as well as the biocompatibility framework that has been investigated so far. Finally, to both capture the growing trend of 2D nanomaterials for biomedical applications and to identify promising new research directions, we provide a critical evaluation of potential applications of recently developed 2D nanomaterials. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. The future of the profession--a survey of dental school applicants.

    Science.gov (United States)

    Stewart, F M J; Drummond, J R; Carson, L; Hoad Reddick, G

    2004-11-13

    To gather background information about applicants to the dental undergraduate course, and ascertain the factors involved in their decision to study dentistry. Applicants attending for interview at Dundee and Manchester Dental Schools completed anonymous questionnaires. The useable response rate was 94% (n = 436). There were equal numbers of male and female applicants to the two schools as a whole. Although there was a much broader ethnic mix in the applicants to Manchester, the overall proportion of minority ethnic groups was considerably greater than in the UK population as a whole. Seventy-five per cent came from professional backgrounds, although marked differences were apparent between ethnic groups. A quarter had family relations who were dentists, and 30% were related to doctors. Over half (53%) decided to apply within the last year, with popular motivating factors including a general interest in dentistry, a desire to help people and to work with their hands. Dentistry was the first choice of career of 89%, with medicine the most popular alternative. Valuable information was gathered from these prospective dental students regarding their backgrounds and the decision process involved in their career selection. This will prove beneficial when developing the recruitment process and allow appropriate tailoring to the target audience.

  16. Microsystems and Nanoscience for Biomedical Applications: A View to the Future

    Science.gov (United States)

    Pilarski, Linda M.; Mehta, Michael D.; Caulfield, Timothy; Kaler, Karan V. I. S.; Backhouse, Christopher J.

    2004-01-01

    At present there is an enormous discrepancy between our nanotechnological capabilities (particularly our nanobiotechnologies), our social wisdom, and consensus on how to apply them. To date, cost considerations have greatly constrained our application of nanotechnologies. However, novel advances in microsystem platform technologies are about to…

  17. The use of concept mapping in measurement development and evaluation: Application and future directions.

    Science.gov (United States)

    Rosas, Scott R; Ridings, John W

    2017-02-01

    The past decade has seen an increase of measurement development research in social and health sciences that featured the use of concept mapping as a core technique. The purpose, application, and utility of concept mapping have varied across this emerging literature. Despite the variety of uses and range of outputs, little has been done to critically review how researchers have approached the application of concept mapping in the measurement development and evaluation process. This article focuses on a review of the current state of practice regarding the use of concept mapping as methodological tool in this process. We systematically reviewed 23 scale or measure development and evaluation studies, and detail the application of concept mapping in the context of traditional measurement development and psychometric testing processes. Although several limitations surfaced, we found several strengths in the contemporary application of the method. We determined concept mapping provides (a) a solid method for establishing content validity, (b) facilitates researcher decision-making, (c) insight into target population perspectives that are integrated a priori, and (d) a foundation for analytical and interpretative choices. Based on these results, we outline how concept mapping can be situated in the measurement development and evaluation processes for new instrumentation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Workshop AccessibleTV "Accessible User Interfaces for Future TV Applications"

    Science.gov (United States)

    Hahn, Volker; Hamisu, Pascal; Jung, Christopher; Heinrich, Gregor; Duarte, Carlos; Langdon, Pat

    Approximately half of the elderly people over 55 suffer from some type of typically mild visual, auditory, motor or cognitive impairment. For them interaction, especially with PCs and other complex devices is sometimes challenging, although accessible ICT applications could make much of a difference for their living quality. Basically they have the potential to enable or simplify participation and inclusion in their surrounding private and professional communities. However, the availability of accessible user interfaces being capable to adapt to the specific needs and requirements of users with individual impairments is very limited. Although there are a number of APIs [1, 2, 3, 4] available for various platforms that allow developers to provide accessibility features within their applications, today none of them provides features for the automatic adaptation of multimodal interfaces being capable to automatically fit the individual requirements of users with different kinds of impairments. Moreover, the provision of accessible user interfaces is still expensive and risky for application developers, as they need special experience and effort for user tests. Today many implementations simply neglect the needs of elderly people, thus locking out a large portion of their potential users. The workshop is organized as part of the dissemination activity for the European-funded project GUIDE "Gentle user interfaces for elderly people", which aims to address this situation with a comprehensive approach for the realization of multimodal user interfaces being capable to adapt to the needs of users with different kinds of mild impairments. As application platform, GUIDE will mainly target TVs and Set-Top Boxes, such as the emerging Connected-TV or WebTV platforms, as they have the potential to address the needs of the elderly users with applications such as for home automation, communication or continuing education.

  19. Study of the behaviour of artificial radioactive aerosols. Applications to some problems of atmospheric circulation (1963); Etude du comportement dcs aerosols radioactifs artificiels. Applications a quelques problemes de circulation atmospherique (1963)

    Energy Technology Data Exchange (ETDEWEB)

    Lambert, G. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1963-11-15

    The aim of this work, consists in the examination of the behaviour of radioactive aerosols produced in the atmosphere by nuclear explosions, in order to deduce the most general laws governing atmospheric circulation and diffusion. After having given a general table of the radioactive aerosols present the authors consider the validity and the precision of the measurement methods and the concentration of the aerosols at ground level and in the upper atmosphere, as well as their deposition on the ground. The existence is thus demonstrated of a tropospheric equatorial barrier and of discontinuous and seasonal aspects of stratosphere-troposphere transfers. The role is shown of precipitations and dry auto-filtration in the lower atmosphere cleaning processes. This work makes it possible to describe the general behaviour of dust from the stratosphere, and to improve the total radioactive contamination of the globe. (author) [French] L'objectif de ce travail consiste a examiner le comportement des aerosols radioactifs introduits dans l'atmosphere par les explosions nucleaires, pour en deduire les lois les plus generals de la circulation et diffusion atmospheriques. Apres avoir dresse un tableau d'ensemble des aerosols radioactifs presents, on examine la validite et la precision des methodes de mesure de leur concentration, au niveau du sol et en haute atmosphere, ainsi que de leur depot a la surface du sol. On met ainsi en evidence l'existence d'une barriere equatoriale tropospherique; l'aspect discontinu et saisonnier des transferts stratosphere-troposphere; le role des precipitations et de l'auto-filtration seche, dans les processus de nettoyage de la basse atmosphere. Ces etudes permettent de decrire le comportement general des poussieres d'origine stratospherique et d'ameliorer le bilan de la contamination radioactive du globe. (auteur)

  20. Therapeutic drug monitoring in pediatric IBD: current application and future perspectives.

    Science.gov (United States)

    Lega, Sara; Bramuzzo, Matteo; Dubinsky, Marla

    2017-09-11

    As the paradigm for IBD management is evolving from symptom control to the more ambitious goal of complete deep remission, the concept of personalized medicine, as a mean to deliver individualized treatment with the best effectiveness and safety profile, is becoming paramount. Therapeutic drug monitoring (TDM) is an essential part of personalized medicine wherein serum drug concentrations are used to guide drug dosing on an individual basis. The concept of TDM has been introduced in the field of IBD along with thiopurines, over a decade ago, and evolved around anti-TNFs therapies. In the era of biologics, TDM entered the clinical field to assist clinicians managing anti-TNF failure and its role is now moving toward the concept of "proactive" TDM with the goal to optimize drug exposure and prevent loss of response. Research in TDM is rapidly expanding: while the role of TDM with new biologics is under investigation, preliminary data suggest that software-systems support tools could be an opportunity to guide dosing choices and maximize the cost-benefit profile of therapies in the near future. The review discusses the current knowledge that poses the rationale for the use of TDM and the present and future role of TDM-based approaches in the management of pediatric IBD. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  1. [Application prospect of human-artificial intelligence system in future manned space flight].

    Science.gov (United States)

    Wei, Jin-he

    2003-01-01

    To make the manned space flight more efficient and safer, a concept of human-artificial (AI) system is proposed in the present paper. The task of future manned space flight and the technique requirement with respect to the human-AI system development were analyzed. The main points are as follows: 1)Astronaut and AI are complementary to each other functionally; 2) Both symbol AI and connectionist AI should be included in the human-AI system, but expert system and Soar-like system are used mainly inside the cabin, the COG-like robots are mainly assigned for EVA either in LEO flight or on the surface of Moon or Mars; 3) The human-AI system is hierarchical in nature with astronaut at the top level; 4) The complex interfaces between astronaut and AI are the key points for running the system reliably and efficiently. As the importance of human-AI system in future manned space flight and the complexity of related technology, it is suggested that the R/D should be planned as early as possible.

  2. The Application of the Logo Language for Future Astronomical PocketQubes and CubeSats

    Science.gov (United States)

    Jernigan, J. Garrett

    2014-06-01

    The PocketQube T-LogoQube was a successful test of a Logo based system for future astronomical CubeSats. The flight and ground software for T-LogoQube is based on the Logo programing language. This flight software is the first use of the Logo language for the control of any satellite. The T-LogoQube team is compised of ~50 people (professional mentors, faculty, and students). The T-LogoQube uLogo based flight system acheived the following goals:(1) Transmission of fours types of packet data with the RFM22B transceiver.(2) Ability to control T-LogoQube with a "one line uLogo program".(3) The uLogo VM includes a unigue time stamp for all data.(4) Past beacon packets are telemetered for a history of T-LogoQube.(5) Realtime flight analysis of the Magnetometer to measure spin rate on orbit(6) Ability to upload new uLogo code to extend the on orbit operation.(7) Single torque coil to point the T-LogoQube spin axis in any direction(8) Detection and ability to correct SEUsWe will present evolution of Logo for future CubeSats for space based astronomy projects.

  3. Green biocides, a promising technology: current and future applications to industry and industrial processes.

    Science.gov (United States)

    Ashraf, Muhammad Aqeel; Ullah, Saleem; Ahmad, Irshad; Qureshi, Ahmad Kaleem; Balkhair, Khaled S; Abdur Rehman, Muhammad

    2014-02-01

    The study of biofilms has skyrocketed in recent years due to increased awareness of the pervasiveness and impact of biofilms. It costs the USA literally billions of dollars every year in energy losses, equipment damage, product contamination and medical infections. But biofilms also offer huge potential for cleaning up hazardous waste sites, filtering municipal and industrial water and wastewater, and forming biobarriers to protect soil and groundwater from contamination. The complexity of biofilm activity and behavior requires research contributions from many disciplines such as biochemistry, engineering, mathematics and microbiology. The aim of this review is to provide a comprehensive analysis of emerging novel antimicrobial techniques, including those using myriad organic and inorganic products as well as genetic engineering techniques, the use of coordination complex molecules, composite materials and antimicrobial peptides and the use of lasers as such or their modified use in combination treatments. This review also addresses advanced and recent modifications, including methodological changes, and biocide efficacy enhancing strategies. This review will provide future planners of biofilm control technologies with a broad understanding and perspective on the use of biocides in the field of green developments for a sustainable future. © 2013 Society of Chemical Industry.

  4. CO{sub 2} direct cycles suitable for AGR type reactors; Cycles directs de gaz carbonique applicables aux reacteurs du genre AGR

    Energy Technology Data Exchange (ETDEWEB)

    Maillet, E. [Commissariat a l' Energie Atomique. Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

    1967-10-01

    The perspectives given by the gas turbines under pressure, to build simple nuclear power plants and acieving significantly high yield, are specified. The CO{sub 2} is characterised by by good efficiency under moderate temperature (500 to 750 Celsius degrees), compactness and the simpleness of machines and the safe exploitation (supply, storage, relief cooling, thermosyphon). The revision of thermal properties of the CO{sub 2} and loss elements show that several direct cycles would fit in particular to the AGR type reactors. Cycles that would diverge a little from classical models and able to lead to power and heat generation can lead by simple means to the best results. Several satisfying solutions present for the starting up, the power regulation and the stopping. The nuclear power plant components and the functioning safety are equally considered in the present report. The conclusions stimulate the studies and realizations of carbon dioxide gas turbines in when approprite. [French] Les perspectives offertes par la turbine a gaz sous pression, pour construire des centrales nucleaires simples et de rendement progressivement eleve, se precisent actuellement. le CO{sub 2} se distingue par sa bonne efficacite a temperature moderee (500 a 750 degres celsius), la compacite et la simplicite des machines, et la surete qu'il apporte a l'exploitation ( approvisionnement, stockage, refroidissement de secours, thermosiphon). La revision des proprietes thermophysiques du CO{sub 2} et des elements de pertes montre que divers cycles directs conviendraient en particulier aux reacteurs agr ou derives. Des cycles s'ecartant peu des modeles classiques, et se pretant ulterieurement a la production simultanee d'electricite et de chaleur, peuvent conduire par des moyens simples aux meilleurs resultats d'ensemble. Plusieurs solutions satisfaisantes se presentent pour le demarrage, le reglage de la puissance et l'arret. Les composants de la centrale et la

  5. USAGE OF ANKI SPECIALISED PROGRAM APPLICATION DURING FUTURE BORDER GUARD OFFICERS’ INDEPENDENT FOREIGN LANGUAGE PROFESSIONAL TRAINING FOR PASSING STATE EXAMINATION

    Directory of Open Access Journals (Sweden)

    Ihor H. Bloshchynskyi

    2017-04-01

    Full Text Available Usage of Anki specialised program application during cadets’ independent foreign language professional training at the National Academy of the State Border Guard Service of Ukraine named after Bohdan Khmelnytskyi who study on specialty «State border security and protection» according to the first (bachelor level of training of higher education for passing state examinations has been revealed in the article. Special attention is given to working out of teaching material (vocabulary decks and cards for the future border guard officers` training according to the following sections of Anki program: studying of nouns, adjectives, pronouns, verbs, word combinations, expressions for interviewing of foreign citizens, etc.

  6. Effet de l'application d'engrais minéral complet NPK et de biochar sur les performances de la culture pure du manioc et de l'association manioc - maïs dans les conditions du plateau des Batéké en République Démocratique du Congo (RDC

    Directory of Open Access Journals (Sweden)

    Lele, B.

    2016-01-01

    Full Text Available Soil Characteristics Under Savanna and Natural Forest on the Bateke Plateau in the Democratic Republic of Congo. In order to develop a sustainable farming system adapted to the conditions of the Batéké plateau, a preliminary trial was conducted between January 2012 and March 2013 at the Ibi agro-forestry domain after a fallow of 10 years (the last three years without destruction of the vegetation by bush fires in sandy soil according to a randomized complete block design with four replications. Five treatments were compared: the cassava sole cropping (Maribuata variety with and without application of 40 kg N, 40 kg P2O5 and 40 kg K2O ha-1, cassava and maize (Samaru variety intercropping with and without application of 40 kg N, 40 kg P2O5 and 40 kg K2O ha-1, and cassava and maize intercropping with application of 40 kg N, 40 kg P2O5, 40 kg K2O ha-1 and 15 t ha-1 of biochar. The results show that in the edaphic and climatic conditions of the test, the simultaneous installation of cassava and maize at the start of short rains provides a gross added value significantly higher than that of cassava sole cropping. The application of mineral fertilizers hardly improves the gross value added for cassava sole cropping while they however benefits to maize when it is associated with cassava in absence of biochar application. The combined application of mineral fertilizer and biochar make it possible to almost double cassava yield and triple the one of maize compared to the no-input control. Gross profit generated by the combination of cassava and maize with mineral fertilizers and biochar application is about twice higher than what is obtained for the control. The combined application of biochar and mineral fertilizer resulted in a significant increase in pH. This should have been accompanied by improved availability of Phosphorus, Calcium and Magnesium in the soil.

  7. Advances for prosthetic technology from historical perspective to current status to future application

    CERN Document Server

    LeMoyne, Robert

    2016-01-01

    This book focuses on the advances in transtibial prosthetic technology and targets research in the evolution of the powered prosthesis such as the BiOM, which was derived from considerable research and development at the Massachusetts Institute of Technology. The concept of the book spans the historical evolution of prosthetic applications from passive to new and futuristic robotic prosthetic technologies.  The author describes the reasons for amputation, surgical procedures, and an historical perspective of the prosthesis for the lower limb. He also addresses the phases and sub-phases of gait and compensatory mechanisms arising for a transtibial prosthesis and links the compensatory mechanisms to long-term morbidities.  The general technologies for gait analysis central to prosthetic design and the inherent biomechanics foundations for analysis are also explored.  The book reports on recent-past to current-term applications with passive elastic prostheses.  The core of the book deals with futuristic robo...

  8. Current and future applications of nanotechnology in plastic and reconstructive surgery

    Directory of Open Access Journals (Sweden)

    Dana K Petersen

    2014-09-01

    Full Text Available Although nanotechnology is a relatively young field, there are countless biomedical applications in use or under investigation. Many specialties have benefitted from nanoscale refinements of diagnostic and therapeutic techniques. Plastic and reconstructive surgery is an incredibly diverse specialty, encompassing craniofacial and hand surgery; trauma, oncologic and congenital reconstruction; burn care, and aesthetic surgery. Advances in nanotechnology have significantly impacted wound management, topical skin care, implant and prosthetic design, tissue engineering, and drug delivery systems. Currently, plastic surgeons are researching the utility of nanoscale tools for bone regeneration, bone prosthetics, and drug delivery. Nanotechnology will continue to build upon preceding discoveries, and its biomedical applications in the field of plastic and reconstructive surgery will expand significantly.

  9. Grid requirements applicable to future NPPs in the new European Electricity Framework

    International Nuclear Information System (INIS)

    Beato Castro, D.; Padill, C. M.

    2000-01-01

    With a view to keeping nuclear energy as an option for future power generation in a competitive market and taking advantage of the current operating experience, a group of European electric utilities have come together to define common requirements for the design and supply of future Light Water Reactor (LWR) plants connected to the electrical system. These requirements, defined with the aim of standardizing and adapting design to the conditions of the new electricity framework, are being included in the European Utility Requirements (EUR) document. Although there are different types of power plants operating appropriately in large electrical systems, the idea is to find the minimum requirements that will allow growth of this type of energy in the European electricity industry without reducing quality, safety and reliability of interconnected electrical systems. It is therefore necessary to take into account the features of the existing power systems and the operating characteristics and design of nuclear power plants so as to harmonize their respective technical peculiarities in the framework of the deregulated electricity sector. The definition of these grid requirements is based primarily on the operating conditions of the Union pour la Coordination de la Production et le Transport de L'Electricite (UCPTE) grid and takes into account the current Grid Code of the main European countries, for the forthcoming Issue C. This paper sets outs the most relevant aspects of the grid requirements, included in Chapter 2.3 of the EUR document Grid Requirements, Issue B, for the connection of future nuclear power plants in the European electricity system, and others that are being considered in the preparation of the new issue of the document that will take into account the deregulated electricity market situation and deal with the following aspects: General characteristics. Operation of a plant under normal grid conditions. Operation of a plant under disturbed grid

  10. Graphene Field Effect Transistors for Biomedical Applications: Current Status and Future Prospects

    Directory of Open Access Journals (Sweden)

    Rhiannan Forsyth

    2017-07-01

    Full Text Available Since the discovery of the two-dimensional (2D carbon material, graphene, just over a decade ago, the development of graphene-based field effect transistors (G-FETs has become a widely researched area, particularly for use in point-of-care biomedical applications. G-FETs are particularly attractive as next generation bioelectronics due to their mass-scalability and low cost of the technology’s manufacture. Furthermore, G-FETs offer the potential to complete label-free, rapid, and highly sensitive analysis coupled with a high sample throughput. These properties, coupled with the potential for integration into portable instrumentation, contribute to G-FETs’ suitability for point-of-care diagnostics. This review focuses on elucidating the recent developments in the field of G-FET sensors that act on a bioaffinity basis, whereby a binding event between a bioreceptor and the target analyte is transduced into an electrical signal at the G-FET surface. Recognizing and quantifying these target analytes accurately and reliably is essential in diagnosing many diseases, therefore it is vital to design the G-FET with care. Taking into account some limitations of the sensor platform, such as Debye–Hükel screening and device surface area, is fundamental in developing improved bioelectronics for applications in the clinical setting. This review highlights some efforts undertaken in facing these limitations in order to bring G-FET development for biomedical applications forward.

  11. Engineering carbon nanomaterials for future applications: energy and bio-sensor

    Science.gov (United States)

    Das, Santanu; Lahiri, Indranil; Kang, Chiwon; Choi, Wonbong

    2011-06-01

    This paper presents our recent results on carbon nanomaterials for applications in energy storage and bio-sensor. More specifically: (i) A novel binder-free carbon nanotubes (CNTs) structure as anode in Li-ion batteries. The interfacecontrolled CNT structure, synthesized through a two-step chemical vapor deposition (CVD) and directly grown on copper current collector, showed very high specific capacity - almost three times as that of graphite, excellent rate capability. (ii) A large scale graphene film was grown on Cu foil by thermal chemical vapor deposition and transferred to various substrates including PET, glass and silicon by using hot press lamination and etching process. The graphene/PET film shows high quality, flexible transparent conductive structure with unique electrical-mechanical properties; ~88.80 % light transmittance and ~ 100 Ω/sq sheet resistance. We demonstrate application of graphene/PET film as flexible and transparent electrode for field emission displays. (iii) Application of individual carbon nanotube as nanoelectrode for high sensitivity electrochemical sensor and device miniaturization. An individual CNT is split into a pair of nanoelectrodes with a gap between them. Single molecular-level detection of DNA hybridization was studied. Hybridization of the probe with its complementary strand results in an appreciable change in the electrical output signal.

  12. Psychrotolerant Sphingobacterium kitahiroshimense LT-2 Isolated from Dhundi Glacier, Himachal Pradesh: Origin Prediction and Future Application.

    Science.gov (United States)

    Sharma, Shivika; Chatterjee, Subhankar

    2018-06-01

    A psychrotolerant bacterium, isolated from Dhundi Glacier, Himachal Pradesh (India) was identified as Sphingobacterium kitahiroshimense LT-2 on the basis of biochemical, molecular and phylogenetic analysis. Sphingobacterium kitahiroshimense was first reported from Japan and was isolated from the city of Kitahiroshima, Hokkaido, Japan. In this report we have discussed about the origin of our strain and predicted that air masses and dust associated microbial cells transportation phenomena may be applicable for the origin of this species in this region. Enzymes and secondary metabolites secreted by the genus Sphingobacterium have enormous potentiality regarding their biotechnological application. Preliminary study of our strain based on metabolic profiling through HPLC showed many new metabolites were secreted by the bacterium when grown in presence of different sugar medium at 28 °C. As far as our knowledge this is the first report about Sphingobacterium species isolated from this region. This preliminary finding will help to draw an idea about the bacterial population in this Himalayan Glaciers (in HP) as well as biotechnological application of this strain can be explored further.

  13. Laser Induced Breakdown Spectroscopy in archeometry: A review of its application and future perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Spizzichino, Valeria, E-mail: valeria.spizzichino@enea.it; Fantoni, Roberta

    2014-09-01

    Laser Induced Breakdown Spectroscopy (LIBS) in the last decades has been more and more applied to the field of Cultural Heritage with great results obtained either alone or in combination with complementary laser techniques. Its ability to analyze, with a minimal loss, different kinds of materials in laboratory, in situ and even in hostile environments has been highly appreciated. The main aim of this paper is to present a review of LIBS applications in the interdisciplinary field of archeometry. The LIBS technique is shortly described both from a theoretical and practical point of view, discussing the instrumental setup, also in comparison with typical features of laser induced fluorescence (LIF) and Raman spectroscopy apparata. The complementary with multivariate analysis, a method that can help in reducing data set dimensions and in pulling out effective information, is stressed. In particular the role of LIBS in Cultural Heritage material characterization, recognition of fakes and indirect dating is described, reporting general considerations and case studies on metal alloys, mural paintings, decorated ceramics, glasses, stones and gems. - Highlights: • Applications of LIBS to archeometry are reviewed. • Complementary among LIBS, LIF, Raman and multivariate analysis is highlighted. • Three major areas of successful LIBS application in archeometry are identified. • Significant results have been presented for several different materials.

  14. Investigations of vapour-phase deposited transition metal dichalcogenide films for future electronic applications

    Science.gov (United States)

    Gatensby, Riley; Hallam, Toby; Lee, Kangho; McEvoy, Niall; Duesberg, Georg S.

    2016-11-01

    Two-dimensional (2D) transitional metal dichalcogenides (TMDs) are of major interest to the research and electrical engineering community. A number of TMDs are semiconducting and have a wide range of bandgaps, they can exhibit n- or p-type behaviour, and the electronic structure changes with the number of layers. These exceptional properties hold much promise for a host of electrical applications including low- or high power field-effect transistors, sensors and diodes. Moreover, the unique optical properties of TMDs make them attractive for optoelectronic applications such as light-emitting diodes, photodiodes, and photovoltaic cells. A prerequisite for all of these applications is a synthesis route which is well controlled, scalable, reproducible and compatible with semiconductor industry process flows. Thermally assisted conversion (TAC), a variant of chemical vapour deposition, shows much promise for meeting these requirements. Herein we review the current progress and challenges of research on 2D semiconducting materials for electronics with a special focus on TAC produced TMD thin films.

  15. Present Status and Future Perspective of Bismuth-Based High-Temperature Superconducting Wires Realizing Application Systems

    Science.gov (United States)

    Sato, Ken-ichi; Kobayashi, Shin-ichi; Nakashima, Takayoshi

    2012-01-01

    Among a series of high-temperature superconducting materials that have been discovered to date, (Bi,Pb)2Sr2Ca2Cu3O10-x is the best candidate for superconducting wires that are long with commercial productivity, and critical current performance. In particular, the controlled overpressure (CT-OP) sintering technique gave us a 100% density of (Bi,Pb)2Sr2Ca2Cu3O10-x portion, which leads to robustness, increase in critical current, and mechanical tolerance. Many application prototypes are already verified and are being evaluated worldwide. Current leads for large magnets and magnetic billet heaters are already commercial products. Commercial applications for power cables, motors for ship propulsion and electric vehicles, and many kinds of magnets are promising in the near future.

  16. The application of computerized content analysis of natural language in psychotherapy research now and in the future.

    Science.gov (United States)

    Gottschalk, L A

    2000-01-01

    For many years the author and his colleagues have been involved in studying the roots and processes of the conveyance of semantic messages via spoken language and verbal texts. After establishing that reliable and valid measurements of highly relevant neuropsychiatric categories, such as anxiety, depression, and cognitive impairment, can be made by identifying and counting the occurrence per grammatical clause of language content and form categories typifying specific content-analysis scales, the research focus has turned towards computerizing this process of content analysis. This report summarizes the achievements and applications of the current empirical status of this method of computerized content analysis of natural language to psychotherapy research, and it speculates on possible future applications in the millennium.

  17. MYRRHA. A European experimental ADS for R and D applications status at mid-2005 and prospective towards future

    International Nuclear Information System (INIS)

    Aiet Abderrahim, Hamid; D'hondt, Pierre

    2005-01-01

    Since 1998, SCK/CEN in partnership with many European research laboratories, is designing a multipurpose ADS for R and D applications - MYRRHA - and is conducting an associated R and D support program. MYRRHA is an Accelerator Driven System (ADS) under development at Mol in Belgium and aiming to serve as a basis for the European experimental ADS to provide protons and neutrons for various R and D applications. It consists of a linac proton accelerator delivering a 350 MeV*5 mA proton beam to a windowless liquid Pb-Bi spallation target that in turn couples to a Pb-Bi cooled, subcritical fast core of 50 MWth. In this paper we report on the status of the MYRRHA project at mid-2005 and prospective towards the future. (author)

  18. Jouer du piano

    Directory of Open Access Journals (Sweden)

    Fériel Kaddour

    2011-04-01

    Full Text Available La réflexion s’appuie dans un premier temps sur une opposition entre deux attitudes de pianistes  à l’égard du travail à l’instrument : Gould, qui revendique une séparation d’avec le clavier pour ne privilégier que la lecture; Arrau, dont la technique au contraire vise à « faire corps » avec son piano. L’étude de ces deux démarches d’interprètes conduit à une conclusion croisée : l’abstraction gouldienne n’est rien d’autre qu’un déplacement du jeu vers d’autres instruments (ceux qui servent à la prise de son et au montage de ses enregistrements ; le « faire-corps » hérité de la culture pianistique romantique est plus dialectique que fusionnel, et en cela implique une capacité de mise à distance. A partir de cette double conclusion, on tâche enfin de repenser la place du jeu à l’instrument dans la mise en œuvre d’une interprétation, en interrogeant le dialogue qui s’instaure entre la partition telle qu’elle s’écrit et le geste tel qu’il se joue.Our study leans on an opposition between two pianists' attitudes about their work with the instrument. Gould claims a necessary separation from the keyboard in order to prioritize reading. Arrau, on the contrary, relies on a technique which consists in “being one” with his piano. The analysis of these two interprets’ behaviours leads to a crossed conclusion: the gouldian abstraction is nothing else than a displacement of the playing towards another kind of instruments, the ones he uses in sound recording and cut up; Arrau’s “being one” is more dialectic than at first sight, and it therefore implies a real distancing from the piano. This constatation leads to rethink the place of the piano playing in the setting of an interpretation, and to highlight the real dialogue which develops itself between the score as it has been written and the gesture as it is played.

  19. Clinical applications for magnetic resonance guided high intensity focused ultrasound (MRgHIFU): present and future

    International Nuclear Information System (INIS)

    Ellis, Samatha; Rieke, Viola; Kohi, Maureen; Westphalen, Antonio C.

    2013-01-01

    It has been well known for decades that high intensity focused ultrasound (HIFU) generates heat in tissues resulting in coagulative necrosis. Implementation, however, has been slow, due to difficulties with finding an appropriate imaging modality that could not only guide treatment, but also provide real-time thermal feedback. These problems have been overcome with the newest magnetic resonance-guided high intensity focused ultrasound systems (MRgHIFU). With its superior spatial resolution enabling accurate image guidance coupled with its ability to provide real-time thermography during treatments, MRI is moving further into the realm of therapeutics for oncologic patient care. This article will discuss the implementation of an MR-guided HIFU system, current clinical indications and touch on future directions.

  20. Super-Resolving Toraldo Pupils for Radio Astronomical Applications: Current Status and Future Prospects

    Science.gov (United States)

    Olmi, Luca

    2017-11-01

    More than half a century ago, in 1952, Giuliano Toraldo di Francia suggested that the resolving power of an optical instrument could be improved using a filter consisting of finite-width concentric coronae of different amplitude and phase transmittance, now known as Toraldo Pupils (TPs). The concept of 'super- resolution' was born, and in the cur- rent literature it is generally associated with various meth- ods for improving the angular resolution of an optical imag- ing system beyond the classical diffraction limit. In the mi- crowave range, the first successful laboratory test of TPs was performed in 2003. These first results suggested that TPs could represent a viable approach to achieve super- resolution in Radio Astronomy. We have therefore started a project devoted to an exhaustive study of TPs and how they could be implemented on a radio telescope. In this work we present a summary of the status of this project, and then we will describe our future plans.

  1. Alginate: Current Use and Future Perspectives in Pharmaceutical and Biomedical Applications

    Directory of Open Access Journals (Sweden)

    Marta Szekalska

    2016-01-01

    Full Text Available Over the last decades, alginates, natural multifunctional polymers, have increasingly drawn attention as attractive compounds in the biomedical and pharmaceutical fields due to their unique physicochemical properties and versatile biological activities. The focus of the paper is to describe biological and pharmacological activity of alginates and to discuss the present use and future possibilities of alginates as a tool in drug formulation. The recent technological advancements with using alginates, issues related to alginates suitability as matrix for three-dimensional tissue cultures, adjuvants of antibiotics, and antiviral agents in cell transplantation in diabetes or neurodegenerative diseases treatment, and an update on the antimicrobial and antiviral therapy of the alginate based drugs are also highlighted.

  2. GigaFitter: Performance at CDF and perspective for future applications

    International Nuclear Information System (INIS)

    Amerio, S.; Annovi, A.; Basile, M.; Bettini, M.; Bucciantonio, M.; Catastini, P.; Cenni, J.; Crescioli, F.; Dell'Orso, M.; Giannetti, P.; Giuliani, E.; Lucchesi, D.; Nicoletto, M.; Piendibene, M.; Rafanelli, N.; Volpi, G.

    2010-01-01

    The Silicon Vertex Trigger (SVT) at CDF is made of two pipelined processors: the Associative Memory finding low precision tracks and the Track Fitter refining the track quality with high-precision fits. We will describe the performance of a next generation track fitter, the GigaFitter, that performs more than a fit per nanosecond. It is going to be inserted parasitically in SVT to study its capabilities to improve data taking during the high luminosity CDF runs. This device is based on modern FPGA technology, rich of powerful DSP arrays, to reduce the track parameter reconstruction to few clock cycles and perform many fits in parallel. The goal of the design was to reduce significantly the processing time required for fitting and thus allow more time for the subsequent high resolution track-fitting. Preliminary results on the algorithm latency are presented. A future more power-full version of the GigaFitter intended for LHC experiments is also discussed.

  3. The application of Big Data in medicine: current implications and future directions.

    Science.gov (United States)

    Austin, Christopher; Kusumoto, Fred

    2016-10-01

    Since the mid 1980s, the world has experienced an unprecedented explosion in the capacity to produce, store, and communicate data, primarily in digital formats. Simultaneously, access to computing technologies in the form of the personal PC, smartphone, and other handheld devices has mirrored this growth. With these enhanced capabilities of data storage and rapid computation as well as real-time delivery of information via the internet, the average daily consumption of data by an individual has grown exponentially. Unbeknownst to many, Big Data has silently crept into our daily routines and, with continued development of cheap data storage and availability of smart devices both regionally and in developing countries, the influence of Big Data will continue to grow. This influence has also carried over to healthcare. This paper will provide an overview of Big Data, its benefits, potential pitfalls, and the projected impact on the future of medicine in general and cardiology in particular.

  4. [Digital luminescence radiography . 2: Technical implementation and clinical application--future developments].

    Science.gov (United States)

    Döhring, W; Urbach, D

    1991-10-30

    In the previously published Part 1 of this paper the basic principle of digital luminescence radiography (DLR) was presented and the technical implementation of the data acquisition system with its advantages and disadvantages as compared with conventional radiography were described [3]. Part 2 covers processing, display, archiving and communication of image data; in addition, suggestions for future improvements in the technique are made. Image processing research is directed towards optimal presentation of the detected data by spatial frequency filtering with unsharp masking and by gradation enhancement. Additional information can be acquired by means of dual energy investigations. The image is displayed on either monitor or transparent X-ray film. Picture archiving requires large storage capacities, and picture communication needs fast transfer rates. At present, about 450 installations for digital luminescence radiography are in clinical use worldwide. Routine use can be expected when technical improvements have been implemented.

  5. The Future of Futures

    DEFF Research Database (Denmark)

    Frankel, Christian; Ossandón, José

    2013-01-01

    Review of Elena Esposito: The Future of Futures. The Time of Money in Financing and Society Cheltenham. Edward Elgar, 2011.......Review of Elena Esposito: The Future of Futures. The Time of Money in Financing and Society Cheltenham. Edward Elgar, 2011....

  6. Advanced ceramic matrix composite materials for current and future propulsion technology applications

    Science.gov (United States)

    Schmidt, S.; Beyer, S.; Knabe, H.; Immich, H.; Meistring, R.; Gessler, A.

    2004-08-01

    Current rocket engines, due to their method of construction, the materials used and the extreme loads to which they are subjected, feature a limited number of load cycles. Various technology programmes in Europe are concerned, besides developing reliable and rugged, low cost, throwaway equipment, with preparing for future reusable propulsion technologies. One of the key roles for realizing reusable engine components is the use of modern and innovative materials. One of the key technologies which concern various engine manufacturers worldwide is the development of fibre-reinforced ceramics—ceramic matrix composites. The advantages for the developers are obvious—the low specific weight, the high specific strength over a large temperature range, and their great damage tolerance compared to monolithic ceramics make this material class extremely interesting as a construction material. Over the past years, the Astrium company (formerly DASA) has, together with various partners, worked intensively on developing components for hypersonic engines and liquid rocket propulsion systems. In the year 2000, various hot-firing tests with subscale (scale 1:5) and full-scale nozzle extensions were conducted. In this year, a further decisive milestone was achieved in the sector of small thrusters, and long-term tests served to demonstrate the extraordinary stability of the C/SiC material. Besides developing and testing radiation-cooled nozzle components and small-thruster combustion chambers, Astrium worked on the preliminary development of actively cooled structures for future reusable propulsion systems. In order to get one step nearer to this objective, the development of a new fibre composite was commenced within the framework of a regionally sponsored programme. The objective here is to create multidirectional (3D) textile structures combined with a cost-effective infiltration process. Besides material and process development, the project also encompasses the development of

  7. Rainfall simulators in hydrological and geomorphological sciences: benefits, applications and future research directions

    Science.gov (United States)

    Iserloh, Thomas; Cerdà, Artemi; Fister, Wolfgang; Seitz, Steffen; Keesstra, Saskia; Green, Daniel; Gabriels, Donald

    2017-04-01

    Rainfall simulators are used extensively within the hydrological and geomorphological sciences and provide a useful investigative tool to understand many processes, such as: (i) plot-scale runoff, infiltration and erosion; (ii) irrigation and crop management, and; (iii) investigations into flooding within a laboratory setting. Although natural rainfall is desirable as it represents actual conditions in a given geographic location, data acquisition relying on natural rainfall is often hindered by its unpredictable nature. Furthermore, rainfall characteristics such as the intensity, duration, drop size distribution and kinetic energy cannot be spatially or temporally regulated or repeated between experimentation. Rainfall simulators provide a suitable method to overcome the issues associated with depending on potentially erratic and unpredictable natural rainfall as they allow: (i) multiple measurements to be taken quickly without waiting for suitable natural rainfall conditions; (ii) the simulation of spatially and/or temporally controlled rainfall patterns over a given plot area, and; (iii) the creation of a closed environment, allowing simplified measurement of input and output conditions. There is no standardisation of rainfall simulation and as such, rainfall simulators differ in their design, rainfall characteristics and research application. Although this impedes drawing meaningful comparisons between studies, this allows researchers to create a bespoke and tailored rainfall simulator for the specific research application. This paper summarises the rainfall simulators used in European research institutions (Universities of Trier, Valencia, Basel, Tuebingen, Wageningen, Loughborough and Ghent) to investigate a number of hydrological and geomorphological issues and includes details on the design specifications (such as the extent and characteristics of simulated rainfall), as well as a discussion of the purpose and application of the rainfall simulator.

  8. La naissance du Purgatoire

    Directory of Open Access Journals (Sweden)

    Laura Mello e Souza

    1983-12-01

    Full Text Available Le Goff, Jacques. La naissance du Purgatoire. Paris, Gallimard, 1981, 509 p. (primeiro parágrafo do texto Desde o período áureo dos Annales e dos escritos de Marc Bloch, Febvre e Braudel, responsáveis por novos rumos na historiografia con-temporânea, os anglo-saxões vêm empanando o brilho dos mestres france-ses . Hobsbawm e Thompson dedicaram estudos clássicos à sociedade pré-industrial e ao mundo da indústria nascente; Wallerstein e Perry Anderson repensaram o absolutismo e a constituição do sistema capitalista, todos eles ilustrando a fecundidade que pode ter a historiografia marxista.

  9. Le sacre du printemps

    Directory of Open Access Journals (Sweden)

    Denise Pumain

    2002-03-01

    Full Text Available Cybergeo aura six ans en avril : dans la réalité du virtuel, dans l'univers récent et fluctuant de la publication en ligne, cela fait de nous, tout à la fois, des pionniers et des vétérans. De façon plus surprenante, il se trouve que nous sommes aussi uniques : parmi toutes les revues électroniques de sciences sociales, aucune ne combine comme Cybergeo ancienneté, publication exclusivement électronique, liberté d'accès au texte intégral, édition et gestion par des chercheurs, et comité de lec...

  10. Today's and future challenges in applications of renewable energy technologies for desalination

    KAUST Repository

    Goosen, Mattheus F A

    2013-08-28

    Recent trends and challenges in applications of renewable energy technologies for water desalination are critically reviewed with an emphasis on environmental concerns and sustainable development. After providing an overview of wind, wave, geothermal, and solar renewable energy technologies for fresh water production, hybrid systems are assessed. Then scale-up and economic factors are considered. This is followed with a section on regulatory factors, environmental concerns, and globalization, and a final segment on selecting the most suitable renewable energy technology for conventional and emerging desalination processes. © 2014 Copyright Taylor & Francis Group, LLC.

  11. Utilisation du semoir philippin, une alternative au repiquage du riz ...

    African Journals Online (AJOL)

    Les avantages tirés de l'utilisation de cet outil sont multiples : économie du temps de travail, homogénéité de répartition des semences, levée uniforme des plantules de riz. En plus, l'utilisation du semoir philippin permet d'économiser les semences de près de 50 % par rapport au repiquage, et d'environ 75 % par rapport ...

  12. Atomic scale engineering of HfO2-based dielectrics for future DRAM applications

    International Nuclear Information System (INIS)

    Dudek, Piotr

    2011-01-01

    Modern dielectrics in combination with appropriate metal electrodes have a great potential to solve many difficulties associated with continuing miniaturization process in the microelectronic industry. One significant branch of microelectronics incorporates dynamic random access memory (DRAM) market. The DRAM devices scaled for over 35 years starting from 4 kb density to several Gb nowadays. The scaling process led to the dielectric material thickness reduction, resulting in higher leakage current density, and as a consequence higher power consumption. As a possible solution for this problem, alternative dielectric materials with improved electrical and material science parameters were intensively studied by many research groups. The higher dielectric constant allows the use of physically thicker layers with high capacitance but strongly reduced leakage current density. This work focused on deposition and characterization of thin insulating layers. The material engineering process was based on Si cleanroom compatible HfO 2 thin films deposited on TiN metal electrodes. A combined materials science and dielectric characterization study showed that Ba-added HfO 2 (BaHfO 3 ) films and Ti-added BaHfO 3 (BaHf 0.5 Ti 0.5 O 3 ) layers are promising candidates for future generation of state-of-the-art DRAMs. In especial a strong increase of the dielectric permittivity k was achieved for thin films of cubic BaHfO 3 (k∝38) and BaHf 0.5 Ti 0.5 O 3 (k∝90) with respect to monoclinic HfO 2 (k∝19). Meanwhile the CET values scaled down to 1 nm for BaHfO 3 and ∝0.8 nm for BaHf 0.5 Ti 0.5 O 3 with respect to HfO 2 (CET=1.5 nm). The Hf 4+ ions substitution in BaHfO 3 by Ti 4+ ions led to a significant decrease of thermal budget from 900 C for BaHfO 3 to 700 C for BaHf 0.5 Ti 0.5 O 3 . Future studies need to focus on the use of appropriate metal electrodes (high work function) and on film deposition process (homogeneity) for better current leakage control. (orig.)

  13. Atomic scale engineering of HfO{sub 2}-based dielectrics for future DRAM applications

    Energy Technology Data Exchange (ETDEWEB)

    Dudek, Piotr

    2011-02-14

    Modern dielectrics in combination with appropriate metal electrodes have a great potential to solve many difficulties associated with continuing miniaturization process in the microelectronic industry. One significant branch of microelectronics incorporates dynamic random access memory (DRAM) market. The DRAM devices scaled for over 35 years starting from 4 kb density to several Gb nowadays. The scaling process led to the dielectric material thickness reduction, resulting in higher leakage current density, and as a consequence higher power consumption. As a possible solution for this problem, alternative dielectric materials with improved electrical and material science parameters were intensively studied by many research groups. The higher dielectric constant allows the use of physically thicker layers with high capacitance but strongly reduced leakage current density. This work focused on deposition and characterization of thin insulating layers. The material engineering process was based on Si cleanroom compatible HfO{sub 2} thin films deposited on TiN metal electrodes. A combined materials science and dielectric characterization study showed that Ba-added HfO{sub 2} (BaHfO{sub 3}) films and Ti-added BaHfO{sub 3} (BaHf{sub 0.5}Ti{sub 0.5}O{sub 3}) layers are promising candidates for future generation of state-of-the-art DRAMs. In especial a strong increase of the dielectric permittivity k was achieved for thin films of cubic BaHfO{sub 3} (k{proportional_to}38) and BaHf{sub 0.5}Ti{sub 0.5}O{sub 3} (k{proportional_to}90) with respect to monoclinic HfO{sub 2} (k{proportional_to}19). Meanwhile the CET values scaled down to 1 nm for BaHfO{sub 3} and {proportional_to}0.8 nm for BaHf{sub 0.5}Ti{sub 0.5}O{sub 3} with respect to HfO{sub 2} (CET=1.5 nm). The Hf{sup 4+} ions substitution in BaHfO{sub 3} by Ti{sup 4+} ions led to a significant decrease of thermal budget from 900 C for BaHfO{sub 3} to 700 C for BaHf{sub 0.5}Ti{sub 0.5}O{sub 3}. Future studies need to focus

  14. Fractals in the neurosciences, Part II: clinical applications and future perspectives.

    Science.gov (United States)

    Di Ieva, Antonio; Esteban, Francisco J; Grizzi, Fabio; Klonowski, Wlodzimierz; Martín-Landrove, Miguel

    2015-02-01

    It has been ascertained that the human brain is a complex system studied at multiple scales, from neurons and microcircuits to macronetworks. The brain is characterized by a hierarchical organization that gives rise to its highly topological and functional complexity. Over the last decades, fractal geometry has been shown as a universal tool for the analysis and quantification of the geometric complexity of natural objects, including the brain. The fractal dimension has been identified as a quantitative parameter for the evaluation of the roughness of neural structures, the estimation of time series, and the description of patterns, thus able to discriminate different states of the brain in its entire physiopathological spectrum. Fractal-based computational analyses have been applied to the neurosciences, particularly in the field of clinical neurosciences including neuroimaging and neuroradiology, neurology and neurosurgery, psychiatry and psychology, and neuro-oncology and neuropathology. After a review of the basic concepts of fractal analysis and its main applications to the basic neurosciences in part I of this series, here, we review the main applications of fractals to the clinical neurosciences for a holistic approach towards a fractal geometry model of the brain. © The Author(s) 2013.

  15. Current status and future direction of nanomedicine: Focus on advanced biological and medical applications

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Mi; Jeong, Hwan Jeong [Dept. of Nuclear Medicine, Molecular Imaging and Therapeutic Medicine Research Center, Cyclotron Research Center, Institute for Medical Science, Chonbuk National University Medical School and Hospital, Jeonju (Korea, Republic of)

    2017-06-15

    Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles, with sizes generally ranging from 1 to 20 nm. These nanotechnologies have been researched tremendously in the last decade and this has led to a new area of “nanomedicine” which is the application of nanotechnology to human health-care for diagnosis, monitoring, treatment, prediction and prevention of diseases. Recently progress has been made in overcoming some of the difficulties in the human use of nanomedicines. In the mid-1990s, Doxil was approved by the FDA, and now various nanoconstructs are on the market and in clinical trials. However, there are many obstacles in the human application of nanomaterials. For translation to clinical use, a detailed understanding is needed of the chemical and physical properties of particles and their pharmacokinetic behavior in the body, including their biodistribution, toxicity, and biocompatibility. In this review, we provide a broad introduction to nanomedicines and discuss the preclinical and clinical trials in which they have been evaluated.

  16. T2* mapping for articular cartilage assessment: principles, current applications, and future prospects.

    Science.gov (United States)

    Hesper, Tobias; Hosalkar, Harish S; Bittersohl, Daniela; Welsch, Götz H; Krauspe, Rüdiger; Zilkens, Christoph; Bittersohl, Bernd

    2014-10-01

    With advances in joint preservation surgery that are intended to alter the course of osteoarthritis by early intervention, accurate and reliable assessment of the cartilage status is critical. Biochemically sensitive MRI techniques can add robust biomarkers for disease onset and progression, and therefore, could be meaningful assessment tools for the diagnosis and follow-up of cartilage abnormalities. T2* mapping could be a good alternative because it would combine the benefits of biochemical cartilage evaluation with remarkable features including short imaging time and the ability of high-resolution three-dimensional cartilage evaluation-without the need for contrast media administration or special hardware. Several in vitro and in vivo studies, which have elaborated on the potential of cartilage T2* assessment in various cartilage disease patterns and grades of degeneration, have been reported. However, much remains to be understood and certain unresolved questions have become apparent with these studies that are crucial to the further application of this technique. This review summarizes the principles of the technique and current applications of T2* mapping for articular cartilage assessment. Limitations of recent studies are discussed and the potential implications for patient care are presented.

  17. Elevated-Temperature Ferritic and Martensitic Steels and Their Application to Future Nuclear Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Klueh, RL

    2005-01-31

    In the 1970s, high-chromium (9-12% Cr) ferritic/martensitic steels became candidates for elevated-temperature applications in the core of fast reactors. Steels developed for conventional power plants, such as Sandvik HT9, a nominally Fe-12Cr-1Mo-0.5W-0.5Ni-0.25V-0.2C steel (composition in wt %), were considered in the United States, Europe, and Japan. Now, a new generation of fission reactors is in the planning stage, and ferritic, bainitic, and martensitic steels are again candidates for in-core and out-of-core applications. Since the 1970s, advances have been made in developing steels with 2-12% Cr for conventional power plants that are significant improvements over steels originally considered. This paper will review the development of the new steels to illustrate the advantages they offer for the new reactor concepts. Elevated-temperature mechanical properties will be emphasized. Effects of alloying additions on long-time thermal exposure with and without stress (creep) will be examined. Information on neutron radiation effects will be discussed as it applies to ferritic and martensitic steels.

  18. Leaf venation: structure, function, development, evolution, ecology and applications in the past, present and future.

    Science.gov (United States)

    Sack, Lawren; Scoffoni, Christine

    2013-06-01

    The design and function of leaf venation are important to plant performance, with key implications for the distribution and productivity of ecosystems, and applications in paleobiology, agriculture and technology. We synthesize classical concepts and the recent literature on a wide range of aspects of leaf venation. We describe 10 major structural features that contribute to multiple key functions, and scale up to leaf and plant performance. We describe the development and plasticity of leaf venation and its adaptation across environments globally, and a new global data compilation indicating trends relating vein length per unit area to climate, growth form and habitat worldwide. We synthesize the evolution of vein traits in the major plant lineages throughout paleohistory, highlighting the multiple origins of individual traits. We summarize the strikingly diverse current applications of leaf vein research in multiple fields of science and industry. A unified core understanding will enable an increasing range of plant biologists to incorporate leaf venation into their research. © 2013 The Authors New Phytologist © 2013 New Phytologist Trust.

  19. NASA's Modern Era Retrospective-Analysis for Research and Applications (MERRA): Early Results and Future Directions

    Science.gov (United States)

    Schubert, Siegfried

    2008-01-01

    This talk will review the status and progress of the NASA/Global Modeling and Assimilation Office (GMAO) atmospheric global reanalysis project called the Modern Era Retrospective-Analysis for Research and Applications (MERRA). An overview of NASA's emerging capabilities for assimilating a variety of other Earth Science observations of the land, ocean, and atmospheric constituents will also be presented. MERRA supports NASA Earth science by synthesizing the current suite of research satellite observations in a climate data context (covering the period 1979-present), and by providing the science and applications communities with of a broad range of weather and climate data with an emphasis on improved estimates of the hydrological cycle. MERRA is based on a major new version of the Goddard Earth Observing System Data Assimilation System (GEOS-5), that includes the Earth System Modeling Framework (ESMF)-based GEOS-5 atmospheric general circulation model and the new NOAA National Centers for Environmental Prediction (NCEP) unified grid-point statistical interpolation (GST) analysis scheme developed as a collaborative effort between NCEP and the GMAO. In addition to MERRA, the GMAO is developing new capabilities in aerosol and constituent assimilation, ocean, ocean biology, and land surface assimilation. This includes the development of an assimilation capability for tropospheric air quality monitoring and prediction, the development of a carbon-cycle modeling and assimilation system, and an ocean data assimilation system for use in coupled short-term climate forecasting.

  20. Current Status and Future Direction of Nanomedicine: Focus on Advanced Biological and Medical Applications.

    Science.gov (United States)

    Kim, Eun-Mi; Jeong, Hwan-Jeong

    2017-06-01

    Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles, with sizes generally ranging from 1 to 20 nm. These nanotechnologies have been researched tremendously in the last decade and this has led to a new area of "nanomedicine" which is the application of nanotechnology to human health-care for diagnosis, monitoring, treatment, prediction and prevention of diseases. Recently progress has been made in overcoming some of the difficulties in the human use of nanomedicines. In the mid-1990s, Doxil was approved by the FDA, and now various nanoconstructs are on the market and in clinical trials. However, there are many obstacles in the human application of nanomaterials. For translation to clinical use, a detailed understanding is needed of the chemical and physical properties of particles and their pharmacokinetic behavior in the body, including their biodistribution, toxicity, and biocompatibility. In this review, we provide a broad introduction to nanomedicines and discuss the preclinical and clinical trials in which they have been evaluated.

  1. Application of habitat thresholds in conservation: Considerations, limitations, and future directions

    Directory of Open Access Journals (Sweden)

    Yntze van der Hoek

    2015-01-01

    Full Text Available Habitat thresholds are often interpreted as the minimum required area of habitat, and subsequently promoted as conservation targets in natural resource policies and planning. Unfortunately, several recent reviews and messages of caution on the application of habitat thresholds in conservation have largely fallen on deaf ears, leading to a dangerous oversimplification and generalization of the concept. We highlight the prevalence of oversimplification/over-generalization of results from habitat threshold studies in policy documentation, the consequences of such over-generalization, and directions for habitat threshold studies that have conservation applications without risking overgeneralization. We argue that in order to steer away from misapplication of habitat thresholds in conservation, we should not focus on generalized nominal habitat values (i.e., amounts or percentages of habitat, but on the use of habitat threshold modeling for comparative exercises of area-sensitivity or the identification of environmental dangers. In addition, we should remain focused on understanding the processes and mechanisms underlying species responses to habitat change. Finally, studies could that focus on deriving nominal value threshold amounts should do so only if the thresholds are detailed, species-specific, and translated to conservation targets particular to the study area only.

  2. Current status and future direction of nanomedicine: Focus on advanced biological and medical applications

    International Nuclear Information System (INIS)

    Kim, Eun Mi; Jeong, Hwan Jeong

    2017-01-01

    Nanotechnology is the engineering and manipulation of materials and devices with sizes in the nanometer range. Colloidal gold, iron oxide nanoparticles and quantum dot semiconductor nanocrystals are examples of nanoparticles, with sizes generally ranging from 1 to 20 nm. These nanotechnologies have been researched tremendously in the last decade and this has led to a new area of “nanomedicine” which is the application of nanotechnology to human health-care for diagnosis, monitoring, treatment, prediction and prevention of diseases. Recently progress has been made in overcoming some of the difficulties in the human use of nanomedicines. In the mid-1990s, Doxil was approved by the FDA, and now various nanoconstructs are on the market and in clinical trials. However, there are many obstacles in the human application of nanomaterials. For translation to clinical use, a detailed understanding is needed of the chemical and physical properties of particles and their pharmacokinetic behavior in the body, including their biodistribution, toxicity, and biocompatibility. In this review, we provide a broad introduction to nanomedicines and discuss the preclinical and clinical trials in which they have been evaluated

  3. Development and application of neuropsychology in Hong Kong: implications of its value and future advancement.

    Science.gov (United States)

    Chan, Agnes S; Sze, Sophia L; Cheung, Mei-Chun; Han, Yvonne M Y

    2016-11-01

    To review the development, application, and value of neuropsychology, and the standard education and training pathway for neuropsychologists or clinical neuropsychologists in Hong Kong. The information provided here was gathered via a literature review of the status of neuropsychology and the validity of commonly adopted neuropsychological tests in Hong Kong. Additional details were acquired via the internet about local tertiary education curricula and the related requirements, the availability of professional associations for licensure or board certification, and relevant statistics/surveys conducted by the government. Some information about the clinical practice of neuropsychology was collected through personal communication with local clinical psychologists. The development of neuropsychology in Hong Kong over the past 20 years is rapid and productive, given the increasing application of advanced neuroimaging techniques, neuropsychological tests, and opportunities for exchanging up-to-date neuropsychological knowledge and professional training through international conferences, workshops, and seminars. Given that neuropsychology services are often provided by clinical psychologists who are master's degree graduates in clinical psychology, the relatively limited training in neuropsychological knowledge and skills and the lack of division for membership or mandatory registration as a neuropsychologist/clinical neuropsychologist may have an impact on the quality of clinical neuropsychological services and the development of this specialty. These findings signify a need for further improvement or refinement of educational and training pathways for neuropsychologist or clinical neuropsychologist along with the recognition of its value in clinical practice through registration of different disciplines of psychology in Hong Kong.

  4. Magnetic resonance angiography with blood-pool contrast agents: future applications

    International Nuclear Information System (INIS)

    Fink, C.; Goyen, M.; Lotz, J.

    2007-01-01

    Blood pool agents remain in the intravascular space for a longer time period. Therefore the optimal imaging window for vascular structures is widened to about 30 minutes. Gadofosveset trisodium (Vasovist, Bayer Schering Pharma AG, Berlin, Germany) is the first blood-pool contrast agent approved in Europe for contrast-enhanced magnetic resonance angiography (MRA) of vessels in the abdomen, pelvis and lower extremity in adults. Other possible applications of blood-pool agents are now being considered, such as assessment of venous thromboembolism, coronary artery disease or sinus venous thrombosis. Perfusion MR imaging holds promise for detecting lung perfusion defects with higher spatial resolution and reduced scan time compared with radionuclide scintigraphy. In coronary artery disease, blood-pool agents enable a substantial increase in the quality of coronary artery imaging. Quantitative myocardial perfusion and myocardial viability seem to be possible, although modifications in protocols and sequence design are necessary for optimal results. Other novel applications of blood-pool agents include monitoring of inflammatory changes in systemic lupus erythematosus and evaluation of tumour invasion into lymph nodes and more reliable assessment of cerebral venous and sinus thrombosis. (orig.)

  5. Hydrogéologie en zone de socle cristallin et cristallophyllien du Sénégal oriental : application de la méthode électrique 1D et 2D à la localisation et à la caractérisation des aquifères du batholite de Saraya et ses environs

    OpenAIRE

    Diouf, Same

    1999-01-01

    Dans la zone du socle cristallin et cristallophyllien du Sénégal oriental, et plus particulièrement dans le secteur du batholite de Saraya, diverses approches conjointes ont été mises en oeuvre en vue de localiser et de caractériser les aquifères, zones favorables à des captages hydrauliques. Il s'agit de la télédétection satellitaire SPOT, de la géologie, de la géophysique (l'électrique 1D et la multiélectrode 2D), de la piézomètrie et de l'hydrochimie. Ces travaux ont permis de : localiser ...

  6. Alimentation du nouveau-ne et du nourrisson dans la region ...

    African Journals Online (AJOL)

    Alimentation du nouveau-ne et du nourrisson dans la region centrale du togo : pratiques familiales et communautaires avant la mise en oeuvre de la strategie « prise en charge integree des maladies de l'enfant »

  7. Future Perspectives of ERAS: A Narrative Review on the New Applications of an Established Approach

    Directory of Open Access Journals (Sweden)

    Dario Bugada

    2016-01-01

    Full Text Available ERAS approach (Enhanced Recovery After Surgery is a multimodal, perioperative pathway designed to achieve early recovery after surgery. ERAS has shown documented efficacy in elective surgery, and the concept of “multimodal” and “multidisciplinary” approach seems still to be of higher importance than each single item within ERAS protocols. New perspectives include the use of ERAS in emergency surgery, where efficacy and safety on outcome have been documented, and flexibility of traditional items may add benefits for traditionally high-risk patients. Obstetric surgery, as well, may open wide horizons for future research, since extremely poor data are currently available, and ERAS benefits may translate even on the baby. Finally, the concept of “outcome” may be extended when considering the specific setting of cancer surgery, in which variables like cancer recurrence, early access to adjuvant therapies, and, finally, long-term survival are as important as the reduced perioperative complications. In this perspective, different items within ERAS protocols should be reinterpreted and eventually integrated towards “protective” techniques, to develop cancer-specific ERAS approaches keeping pace with the specific aims of oncologic surgery.

  8. Neuroprosthetics of the upper extremity--clinical application in spinal cord injury and future perspectives.

    Science.gov (United States)

    Rupp, R; Gerner, H J

    2004-04-01

    Within the last couple of years, partial restoration of lost motor functions in a larger number of spinal cord injured patients has become possible by the introduction of neuroprostheses into the clinical environment. The Freehand system in particular is the first implantable neuroprosthesis from which a certain group of tetraplegic patients with stable shoulder function, but missing or weak grasp and hold function of the hand do benefit. The system is based on the combination of electrical stimulation and operative tendon transfers and thus represents a multicomponent concept for long-term restoration of the grasp function. The crucial prerequisites for successful use of an implantable neuroprosthesis are the right indication, careful preoperative muscle stimulation, differentiated planning of the surgery and functional training adopted to the individual residual functions. After successful completion of an extensive rehabilitation program, patients are able to use the system for activities of daily living without the need for special additional aids, which enhances their quality of life and independency. In order to extend the group of potential users of neuroprostheses in the future, new technological developments will have to take into account that nowadays the majority of spinal cord injured patients suffer from an incomplete lesion of the spinal cord. For these particular patients who still possess residual functions, modular, "naturally" controllable systems for supporting these functions are needed rather than complex systems to substitute them.

  9. High magnetic field science and its application in the United States current status and future directions

    CERN Document Server

    National Research Council of the National Academies

    2013-01-01

    The Committee to Assess the Current Status and Future Direction of High Magnetic Field Science in the United States was convened by the National Research Council in response to a request by the National Science Foundation. This report answers three questions: (1) What is the current state of high-field magnet science, engineering, and technology in the United States, and are there any conspicuous needs to be addressed? (2) What are the current science drivers and which scientific opportunities and challenges can be anticipated over the next ten years? (3) What are the principal existing and planned high magnetic field facilities outside of the United States, what roles have U.S. high field magnet development efforts played in developing those facilities, and what potentials exist for further international collaboration in this area? A magnetic field is produced by an electrical current in a metal coil. This current exerts an expansive force on the coil, and a magnetic field is "high" if it challenges the str...

  10. Advancing vector biology research: a community survey for future directions, research applications and infrastructure requirements.

    Science.gov (United States)

    Kohl, Alain; Pondeville, Emilie; Schnettler, Esther; Crisanti, Andrea; Supparo, Clelia; Christophides, George K; Kersey, Paul J; Maslen, Gareth L; Takken, Willem; Koenraadt, Constantianus J M; Oliva, Clelia F; Busquets, Núria; Abad, F Xavier; Failloux, Anna-Bella; Levashina, Elena A; Wilson, Anthony J; Veronesi, Eva; Pichard, Maëlle; Arnaud Marsh, Sarah; Simard, Frédéric; Vernick, Kenneth D

    2016-01-01

    Vector-borne pathogens impact public health, animal production, and animal welfare. Research on arthropod vectors such as mosquitoes, ticks, sandflies, and midges which transmit pathogens to humans and economically important animals is crucial for development of new control measures that target transmission by the vector. While insecticides are an important part of this arsenal, appearance of resistance mechanisms is increasingly common. Novel tools for genetic manipulation of vectors, use of Wolbachia endosymbiotic bacteria, and other biological control mechanisms to prevent pathogen transmission have led to promising new intervention strategies, adding to strong interest in vector biology and genetics as well as vector-pathogen interactions. Vector research is therefore at a crucial juncture, and strategic decisions on future research directions and research infrastructure investment should be informed by the research community. A survey initiated by the European Horizon 2020 INFRAVEC-2 consortium set out to canvass priorities in the vector biology research community and to determine key activities that are needed for researchers to efficiently study vectors, vector-pathogen interactions, as well as access the structures and services that allow such activities to be carried out. We summarize the most important findings of the survey which in particular reflect the priorities of researchers in European countries, and which will be of use to stakeholders that include researchers, government, and research organizations.

  11. Pediatric Fear-Avoidance Model of Chronic Pain: Foundation, Application and Future Directions

    Directory of Open Access Journals (Sweden)

    Gordon JG Asmundson

    2012-01-01

    Full Text Available The fear-avoidance model of chronic musculoskeletal pain has become an increasingly popular conceptualization of the processes and mechanisms through which acute pain can become chronic. Despite rapidly growing interest and research regarding the influence of fear-avoidance constructs on pain-related disability in children and adolescents, there have been no amendments to the model to account for unique aspects of pediatric chronic pain. A comprehensive understanding of the role of fear-avoidance in pediatric chronic pain necessitates understanding of both child/adolescent and parent factors implicated in its development and maintenance. The primary purpose of the present article is to propose an empirically-based pediatric fear-avoidance model of chronic pain that accounts for both child/adolescent and parent factors as well as their potential interactive effects. To accomplish this goal, the present article will define important fear-avoidance constructs, provide a summary of the general fear-avoidance model and review the growing empirical literature regarding the role of fear-avoidance constructs in pediatric chronic pain. Assessment and treatment options for children with chronic pain will also be described in the context of the proposed pediatric fear-avoidance model of chronic pain. Finally, avenues for future investigation will be proposed.

  12. Current applications and potential future role of wireless capsule technology in Crohn's disease.

    Science.gov (United States)

    Hall, Barry; Holleran, Grainne; McNamara, Deirdre

    2014-11-01

    The development of capsule technology has modified our approach to the diagnosis of gastrointestinal disease. The relatively rapid uptake of capsule endoscopy as an important clinical tool can be largely ascribed to a number of key factors, including the fact that it is a relatively easy examination to perform in an outpatient setting. It has been established as an integral part of the investigation pathway for obscure gastrointestinal bleeding and suspected small bowel Crohn's disease (CD). CURRENT USE OF CAPSULE ENDOSCOPY: Small bowel CD can be a challenging entity to diagnose. Capsule endoscopy has been shown to be both useful and safe in patients with both suspected and established small bowel CD. In suspected disease, capsule endoscopy has both a high diagnostic yield and negative predictive value. Capsule findings lead to changes in management in up to 73% of patients with established CD. However, while the technology appears capable of detecting subtle mucosal changes not readily apparent on alternate imaging modalities, the question of what actually constitutes small bowel CD as described by capsule is an issue that remains unresolved to date. Thus, capsule endoscopy is best utilised in tandem with advanced imaging and endoscopic techniques such as balloon- assisted enteroscopy. The development of a capsule capable of viewing the colon coupled with improvements in image quality and battery life are likely to lead to the increasing uptake of this technology. In the future, 'interactive' capsules with the ability to view the entire gastrointestinal tract may be a reality.

  13. The explanatory power of Schema Theory: theoretical foundations and future applications in Ergonomics.

    Science.gov (United States)

    Plant, Katherine L; Stanton, Neville A

    2013-01-01

    Schema Theory is intuitively appealing although it has not always received positive press; critics of the approach argue that the concept is too ambiguous and vague and there are inherent difficulties associated with measuring schemata. As such, the term schema can be met with scepticism and wariness. The purpose of this paper is to address the criticisms that have been levelled at Schema Theory by demonstrating how Schema Theory has been utilised in Ergonomics research, particularly in the key areas of situation awareness, naturalistic decision making and error. The future of Schema Theory is also discussed in light of its potential roles as a unifying theory in Ergonomics and in contributing to our understanding of distributed cognition. We conclude that Schema Theory has made a positive contribution to Ergonomics and with continued refinement of methods to infer and represent schemata it is likely that this trend will continue. This paper reviews the contribution that Schema Theory has made to Ergonomics research. The criticisms of the theory are addressed using examples from the areas of situation awareness, decision making and error.

  14. Novel applications of the temporal kernel method: Historical and future radiative forcing

    Science.gov (United States)

    Portmann, R. W.; Larson, E.; Solomon, S.; Murphy, D. M.

    2017-12-01

    We present a new estimate of the historical radiative forcing derived from the observed global mean surface temperature and a model derived kernel function. Current estimates of historical radiative forcing are usually derived from climate models. Despite large variability in these models, the multi-model mean tends to do a reasonable job of representing the Earth system and climate. One method of diagnosing the transient radiative forcing in these models requires model output of top of the atmosphere radiative imbalance and global mean temperature anomaly. It is difficult to apply this method to historical observations due to the lack of TOA radiative measurements before CERES. We apply the temporal kernel method (TKM) of calculating radiative forcing to the historical global mean temperature anomaly. This novel approach is compared against the current regression based methods using model outputs and shown to produce consistent forcing estimates giving confidence in the forcing derived from the historical temperature record. The derived TKM radiative forcing provides an estimate of the forcing time series that the average climate model needs to produce the observed temperature record. This forcing time series is found to be in good overall agreement with previous estimates but includes significant differences that will be discussed. The historical anthropogenic aerosol forcing is estimated as a residual from the TKM and found to be consistent with earlier moderate forcing estimates. In addition, this method is applied to future temperature projections to estimate the radiative forcing required to achieve those temperature goals, such as those set in the Paris agreement.

  15. A review on alum sludge reuse with special reference to agricultural applications and future challenges.

    Science.gov (United States)

    Dassanayake, K B; Jayasinghe, G Y; Surapaneni, A; Hetherington, C

    2015-04-01

    Alum salts are commonly used in the water industry to promote coagulation in the production of clean drinking water, which results in the generation and accumulation of 'waste' by-product 'alum sludge' in large volumes. Effective and efficient management of alum sludge in an economically and environmentally sustainable manner remains a significant social and environmental concern with ever increasing demand for potable water as a result of rapidly escalating world population and urban expansion. Various intensive practices have been employed to reuse the alum sludge in an attempt to figure out how to fill the gap between successful drinking water treatment process and environmentally friendly alum sludge management for over the years. This paper primarily aimed at comprehensive review of the existing literature on alum sludge characteristics, its environmental concerns and their potential utilization, especially in agricultural and horticultural sectors leading to update our recent state of knowledge and formulate a compendium of present and past developments. Different types of alum sludge utilizations in various fields were recognized and examined. The strengths, weaknesses, opportunities and potential risks of alum sludge reuse options with particular reference to agriculture were highlighted and knowledge gaps were identified. Research priorities and future challenges that will support in the development of effective alumsludgemanagement practices in agriculture with multi-prong strategies were discussed. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. The application of radiation technology in industrial processes: current and future perspectives

    International Nuclear Information System (INIS)

    Silverman, J.

    1975-01-01

    The development of nuclear power has been responsible for many by-products, among them radioactive fission products. In the late 1940's and early 1950's considerable efforts were made to develop industrial processes that could make use of the fission products in large quantities. Although some fission products are utilized today, the scale does not approach the quantities that will be produced in a nuclear economy. The efforts have not been a failure, however, and the research to develop industrial processes has created markets, not for the fission products as one had hoped, but for the radioisotope Cobalt-60 produced by neutron capture in a nuclear reactor, and for accelerators - machines that produce radiation in a controlled manner. Success in finding uses for the major fission products may yet come, as research continues in the radiation chemistry and radiation biology fields. Radiation processing is now a vigorously expanding area because of sharp increases in the reliability of electron beam generators, sharp drops in the unit cost of both electron beam power and electron beam energy, significant advances in radiation chemistry leading to lower dose requirements and increased engineering knowledge and practical experience. he principal reasons for its bright future promise arise from expectations of further sharp decreases in the unit cost of electron beam energy and from the recent successful adoption of radiation on a large scale for cross linking of telephone wire insulation in the United States. (author)

  17. Future sustainability forecasting by exchange markets: basic theory and an application.

    Science.gov (United States)

    Malyshkina, Nataliya; Niemeier, Deb

    2010-12-01

    Setting sustainability targets and evaluating systems progress are of great importance nowadays due to threats to the human society, to economic development and to ecosystems, posed by unsustainable human activities. This research establishes a probabilistic theoretical approach based on market expectations reflected in prices of publicly traded securities to estimate the time horizon until the appearance of new technologies related to replacement of nonrenewable resources, for example, crude oil and oil products. To assess time T when technological innovations are likely to appear, we apply advanced pricing equations, based on a stochastic discount factor to those traded securities whose future cash flows critically depend on appearance of such innovations. In a simple approximation of the proposed approach applied to replacement of crude oil and oil products, we obtain T ≈ (P(0)(oil)/C(0))·ln (Δ·P(0)(oil)/P(0)(alt)), where P(0)(oil) and P(0)(alt) are the current aggregate market capitalizations of oil and alternative-energy companies, C(0) is the annual aggregate dividends that oil companies pay to their shareholders at the present, and Δ is the fraction of the oil (oil products) replaced at time T. This formula gives T ≈ 131 years for replacement of gasoline and diesel. The proposed market-expectations approach may allow policymakers to effectively develop policies and plan for long-term changes.

  18. ASAS centennial paper: net energy systems for beef cattle--concepts, application, and future models.

    Science.gov (United States)

    Ferrell, C L; Oltjen, J W

    2008-10-01

    Development of nutritional energetics can be traced to the 1400s. Lavoisier established relationships among O(2) use, CO(2) production and heat production in the late 1700s, and the laws of thermodynamics and law of Hess were discovered during the 1840s. Those discoveries established the fundamental bases for nutritional energetics and enabled the fundamental entity ME = retained energy + heat energy to be established. Objectives became: 1) to establish relationships between gas exchange and heat energy, 2) to devise bases for evaluation of foods that could be related to energy expenditures, and 3) to establish causes of energy expenditures. From these endeavors, the basic concepts of energy partitioning by animals were developed, ultimately resulting in the development of feeding systems based on NE concepts. The California Net Energy System, developed for finishing beef cattle, was the first to be based on retained energy as determined by comparative slaughter and the first to use 2 NE values (NE(m) and NE(g)) to describe feed and animal requirements. The system has been broadened conceptually to encompass life cycle energy requirements of beef cattle and modified by the inclusion of numerous adjustments to address factors known to affect energy requirements and value of feed to meet those needs. The current NE system remains useful but is empirical and static in nature and thus fails to capture the dynamics of energy utilization by diverse animals as they respond to changing environmental conditions. Consequently, efforts were initiated to develop dynamic simulation models that captured the underlying biology and thus were sensitive to variable genetic and environmental conditions. Development of a series of models has been described to show examples of the conceptual evolution of dynamic, mechanistic models and their applications. Generally with each new system, advances in prediction accuracy came about by adding new terms to conceptually validated models

  19. Machine learning applications in proteomics research: how the past can boost the future.

    Science.gov (United States)

    Kelchtermans, Pieter; Bittremieux, Wout; De Grave, Kurt; Degroeve, Sven; Ramon, Jan; Laukens, Kris; Valkenborg, Dirk; Barsnes, Harald; Martens, Lennart

    2014-03-01

    Machine learning is a subdiscipline within artificial intelligence that focuses on algorithms that allow computers to learn solving a (complex) problem from existing data. This ability can be used to generate a solution to a particularly intractable problem, given that enough data are available to train and subsequently evaluate an algorithm on. Since MS-based proteomics has no shortage of complex problems, and since publicly available data are becoming available in ever growing amounts, machine learning is fast becoming a very popular tool in the field. We here therefore present an overview of the different applications of machine learning in proteomics that together cover nearly the entire wet- and dry-lab workflow, and that address key bottlenecks in experiment planning and design, as well as in data processing and analysis. © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. POTENTIAL AND FUTURE TRENDS ON INDUSTRIAL RADIATION PROCESSING TECHNOLOGY APPLICATION IN EMERGING COUNTRY - BRAZIL

    Energy Technology Data Exchange (ETDEWEB)

    Sampa, M.H.O.; Omi, N.M.; Rela, C.S.; Tsai, D.

    2004-10-06

    Brazil started the use of radiation technology in the seventies on crosslinking polyethylene for insulation of wire and electronic cables and sterilization of medical care devices. The present status of industrial applications of radiation shows that the use of this technology is increasing according to the economical development and the necessity to become the products manufactured in the local industries competitive in quality and price for internal and external market. The on going development activities in this area are concentrated on polymers processing (materials modification), foodstuff treatment and environmental protection. The development, the promotion and the technical support to consolidate this technology to the local industries is the main attribution of Institute for Energetic and Nuclear Research-IPEN, a governmental Institution.

  1. Advances in Gammalloy Materials-Processes-Application Technology: Successes, Dilemmas, and Future

    Science.gov (United States)

    Kim, Young-Won; Kim, Sang-Lan

    2018-04-01

    For the last several years, gamma titanium aluminide ( γ-TiAl)-based alloys, called "gammalloys," in specific alloy-microstructure forms began to be implemented in civil aero-engines as cast or wrought low-pressure turbine (LPT) blades and in select ground vehicle engines as cast turbocharger rotors and wrought exhaust valves. Their operation temperatures are approximately up to 750°C for LPT blades and around 1000°C for turbocharger rotors. This article critically assesses current engineering gammalloys and their limitations and introduces eight strengthening pathways that can be adopted immediately for the development of advanced, higher temperature gammalloys. Intelligent integration of the pathways into the emerging application-specific research and development processes is emphasized as the key to the advancement of the gammalloy technology to the next higher engineering performance levels.

  2. Unmanned aircraft systems in wildlife research: Current and future applications of a transformative technology

    Science.gov (United States)

    Christie, Katherine S.; Gilbert, Sophie L.; Brown, Casey L.; Hatfield, Michael; Hanson, Leanne

    2016-01-01

    Unmanned aircraft systems (UAS) – also called unmanned aerial vehicles (UAVs) or drones – are an emerging tool that may provide a safer, more cost-effective, and quieter alternative to traditional research methods. We review examples where UAS have been used to document wildlife abundance, behavior, and habitat, and illustrate the strengths and weaknesses of this technology with two case studies. We summarize research on behavioral responses of wildlife to UAS, and discuss the need to understand how recreational and commercial applications of this technology could disturb certain species. Currently, the widespread implementation of UAS by scientists is limited by flight range, regulatory frameworks, and a lack of validation. UAS are most effective when used to examine smaller areas close to their launch sites, whereas manned aircraft are recommended for surveying greater distances. The growing demand for UAS in research and industry is driving rapid regulatory and technological progress, which in turn will make them more accessible and effective as analytical tools.

  3. Advances in Gammalloy Materials-Processes-Application Technology: Successes, Dilemmas, and Future

    Science.gov (United States)

    Kim, Young-Won; Kim, Sang-Lan

    2018-02-01

    For the last several years, gamma titanium aluminide (γ-TiAl)-based alloys, called "gammalloys," in specific alloy-microstructure forms began to be implemented in civil aero-engines as cast or wrought low-pressure turbine (LPT) blades and in select ground vehicle engines as cast turbocharger rotors and wrought exhaust valves. Their operation temperatures are approximately up to 750°C for LPT blades and around 1000°C for turbocharger rotors. This article critically assesses current engineering gammalloys and their limitations and introduces eight strengthening pathways that can be adopted immediately for the development of advanced, higher temperature gammalloys. Intelligent integration of the pathways into the emerging application-specific research and development processes is emphasized as the key to the advancement of the gammalloy technology to the next higher engineering performance levels.

  4. Rhamnolipid biosurfactants: evolutionary implications, applications and future prospects from untapped marine resource.

    Science.gov (United States)

    Kiran, George Seghal; Ninawe, Arun Shivanth; Lipton, Anuj Nishanth; Pandian, Vijayalakshmi; Selvin, Joseph

    2016-01-01

    Rhamnolipid-biosurfactants are known to be produced by the genus Pseudomonas, however recent literature reported that rhamnolipids (RLs) are distributed among diverse microbial genera. To integrate the evolutionary implications of rhamnosyl transferase among various groups of microorganisms, a comprehensive comparative motif analysis was performed amongst bacterial producers. Findings on new RL-producing microorganism is helpful from a biotechnological perspective and to replace infective P. aeruginosa strains which ultimately ensure industrially safe production of RLs. Halotolerant biosurfactants are required for efficient bioremediation of marine oil spills. An insight on the exploitation of marine microbes as the potential source of RL biosurfactants is highlighted in the present review. An economic production process, solid-state fermentation using agro-industrial and industrial waste would increase the scope of biosurfactants commercialization. Potential and prospective applications of RL-biosurfactants including hydrocarbon bioremediation, heavy metal removal, antibiofilm activity/biofilm disruption and greener synthesis of nanoparticles are highlighted in this review.

  5. POTENTIAL AND FUTURE TRENDS ON INDUSTRIAL RADIATION PROCESSING TECHNOLOGY APPLICATION IN EMERGING COUNTRY - BRAZIL

    International Nuclear Information System (INIS)

    Sampa, M.H.O.; Omi, N.M.; Rela, C.S.; Tsai, D.

    2004-01-01

    Brazil started the use of radiation technology in the seventies on crosslinking polyethylene for insulation of wire and electronic cables and sterilization of medical care devices. The present status of industrial applications of radiation shows that the use of this technology is increasing according to the economical development and the necessity to become the products manufactured in the local industries competitive in quality and price for internal and external market. The on going development activities in this area are concentrated on polymers processing (materials modification), foodstuff treatment and environmental protection. The development, the promotion and the technical support to consolidate this technology to the local industries is the main attribution of Institute for Energetic and Nuclear Research-IPEN, a governmental Institution

  6. Applications of ECH on the DIII-D tokamak and projections for future ECH upgrades

    Directory of Open Access Journals (Sweden)

    Solomon W.M.

    2012-09-01

    Full Text Available Electron Cyclotron Heating and Current Drive plays an important role in the DIII-D program. In high performance discharges EC power contributes greatly to MHD stability, and this is particularly important for discharges with low rotational torque applied, as will be the case for ITER. Off-axis EC current drive also plays a key role in the actualization of steady-state scenarios by supporting the desired current profile. In order to carry out these applications at higher beta and higher field, an upgrade of the EC power to 15 MW is needed, and the best gyrotron frequency for the DIII-D program is 117.5 GHz.

  7. Present stage, applications and future prospects of on-line control in spent fuel processing plants

    International Nuclear Information System (INIS)

    Edeline, J.C.

    1977-01-01

    Apparatus more currently used in France for on-line control in spent fuel processing plants are presented. Most of such apparatus were developed from the 'Services d'Electronique de Saclay' of the French Atomic Energy Commission (CEA), for physical, physico-chemical, and radiometric measurements. The applications of on-line sensors are illustrated by the automatic control system of the third stage of purification in the pilot plant at Marcoule. Some devices in project or on testing are also described, which are intended for isotope determination in decontaminated uranium solutions (0.4mCiγ/kg), or determination of U and Pu contents in solutions or of U trace amounts in wastes (1mgl -1 ) [fr

  8. Poly(Lactic-co-Glycolic Acid: Applications and Future Prospects for Periodontal Tissue Regeneration

    Directory of Open Access Journals (Sweden)

    Xiaoyu Sun

    2017-06-01

    Full Text Available Periodontal tissue regeneration is the ultimate goal of the treatment for periodontitis-affected teeth. The success of regenerative modalities relies heavily on the utilization of appropriate biomaterials with specific properties. Poly (lactic-co-glycolic acid (PLGA, a synthetic aliphatic polyester, has been actively investigated for periodontal therapy due to its favorable mechanical properties, tunable degradation rates, and high biocompatibility. Despite the attractive characteristics, certain constraints associated with PLGA, in terms of its hydrophobicity and limited bioactivity, have led to the introduction of modification strategies that aimed to improve the biological performance of the polymer. Here, we summarize the features of the polymer and update views on progress of its applications as barrier membranes, bone grafts, and drug delivery carriers, which indicate that PLGA can be a good candidate material in the field of periodontal regenerative medicine.

  9. The Application and Future of Big Database Studies in Cardiology: A Single-Center Experience.

    Science.gov (United States)

    Lee, Kuang-Tso; Hour, Ai-Ling; Shia, Ben-Chang; Chu, Pao-Hsien

    2017-11-01

    As medical research techniques and quality have improved, it is apparent that cardiovascular problems could be better resolved by more strict experiment design. In fact, substantial time and resources should be expended to fulfill the requirements of high quality studies. Many worthy ideas and hypotheses were unable to be verified or proven due to ethical or economic limitations. In recent years, new and various applications and uses of databases have received increasing attention. Important information regarding certain issues such as rare cardiovascular diseases, women's heart health, post-marketing analysis of different medications, or a combination of clinical and regional cardiac features could be obtained by the use of rigorous statistical methods. However, there are limitations that exist among all databases. One of the key essentials to creating and correctly addressing this research is through reliable processes of analyzing and interpreting these cardiologic databases.

  10. Sustainability Assessment of Future Scenarios: Methodology and Application to Mountain Areas of Europe

    Science.gov (United States)

    Sheate, William R.; Partidário, Maria Rosário Do; Byron, Helen; Bina, Olivia; Dagg, Suzan

    2008-02-01

    BioScene (scenarios for reconciling biodiversity conservation with declining agriculture use in mountain areas in Europe) was a three-year project (2002 2005) funded by the European Union’s Fifth Framework Programme, and aimed to investigate the implications of agricultural restructuring and decline for biodiversity conservation in the mountain areas of Europe. The research took a case study approach to the analysis of the biodiversity processes and outcomes of different scenarios of agri-environmental change in six countries (France, Greece, Norway, Slovakia, Switzerland, and the United Kingdom) covering the major biogeographical regions of Europe. The project was coordinated by Imperial College London, and each study area had a multidisciplinary team including ecologists and social and economic experts, which sought a comprehensive understanding of the drivers for change and their implications for sustainability. A key component was the sustainability assessment (SA) of the alternative scenarios. This article discusses the development and application of the SA methodology developed for BioScene. While the methodology was objectives-led, it was also strongly grounded in baseline ecological and socio-economic data. This article also describes the engagement of stakeholder panels in each study area and the use of causal chain analysis for understanding the likely implications for land use and biodiversity of strategic drivers of change under alternative scenarios for agriculture and rural policy and for biodiversity management. Finally, this article draws conclusions for the application of SA more widely, its use with scenarios, and the benefits of stakeholder engagement in the SA process.

  11. Current and future applications of protons in medical imaging and treatment

    International Nuclear Information System (INIS)

    Schulte, Reinhard W.

    2011-01-01

    Protons have a more than 50-year history of applications in medical therapy and more recently also in imaging. Therapy with protons became possible after proton accelerators capable of accelerating protons to energies higher than 150 MeV had been built during the 1940s in a few places around the world. Proton radiography experiments started at the Harvard Cyclotron in the early 1960s. Physicist Allan Cormack, who shared the Nobel Prize for laying the foundation of computed tomography together with Sir Godfrey Hounsfield in 1979, suggested that protons can be used for tomographic imaging for the first time in 1963. Proton CT requires a rotating proton gantry, which did not become available until 1991, at our institution. The interest in proton CT has been renewed due to the fact that exact proton treatment planning is only possible with accurate knowledge of the relative proton stopping power distribution (with respect to water) of the patient, which is best derived by using protons for imaging. Early attempts to do proton CT were hampered by the lack of high-resolution particle trackers, fast data acquisition electronics, and sufficient computing power. Also, efficient proton CT reconstruction algorithms had to be developed that can handle reconstruction based on a large number of proton histories, taking into account the non-straight probabilistic paths of multiply scattered protons. Most of these challenges have been or are about to be solved with the help of high-energy and particle physicists, computer science engineers, and applied mathematicians. In this talk, I will give an update on the development of proton CT for applications in proton therapy. This is an update from a talk I gave at the Annual Brazilian Physics Meeting in 2001, when I first suggested that physicists should contribute to the development of modern proton CT. Brazilian physicists have provided many valuable ideas and discussions for this exciting development. (author)

  12. Application of current and future satellite missions to hydrologic prediction in transboundary rivers

    Science.gov (United States)

    Biancamaria, S.; Clark, E.; Lettenmaier, D. P.

    2010-12-01

    temporal repeat (10 days for current satellites) and to gaps in the water mask, water volume estimates are meaningful only at the monthly scale. Furthermore, this information is limited to channels with wider than 250-500 m. The future Surface Water and Ocean Topography (SWOT) mission, which is intended to be launched in 2020, will provide global maps of water elevations, with a spatial resolution of 100 m and errors on the water elevation equal to or below 10 cm. The SWOT Ka band interferometric Synthetic Aperture Radar (SAR), will not be affected by cloud cover (aside from infrequent heavy rain); therefore, estimation of the water volume change on the Ganges and on the Brahmaputra upstream to the Bangladesh provided by SWOT should be much more accurate in space and time than can currently be achieved. We discuss the implications of future SWOT observations in the context of our preliminary work on the Ganges-Brahmaputra Rivers using current generation satellite data.

  13. Implementation of comparative effectiveness research in personalized medicine applications in oncology: current and future perspectives

    Directory of Open Access Journals (Sweden)

    IJzerman MJ

    2015-11-01

    Full Text Available Maarten J IJzerman,1,3 Andrea Manca,2,3 Julia Keizer,1 Scott D Ramsey4 1Department of Health Technology and Services Research, University of Twente, Enschede, the Netherlands; 2Centre for Health Economics, University of York, York, UK; 3Department of Population Health, Luxembourg Institute of Health, Strassen, Luxembourg, 4Fred Hutchinson Cancer Research Center, Seattle, WA, USAAbstract: Personalized medicine (PM or precision medicine has been defined as an innovative approach that takes into account individual differences in people's genes, environments, and lifestyles in prevention and treatment of disease. In PM, genomic information may contribute to the molecular understanding of disease, to optimize preventive health care strategies, and to fit the best drug therapies to the patient's individual characteristics. Evidence development in the era of genomic medicine is extremely challenging due to a number of factors. These include the rapid technological innovation in molecular diagnostics and targeted drug discoveries, and hence the large number of mutations and multiple ways these may influence treatment decisions. Although the evidence base for PM is evolving rapidly, the main question to be explored in this article is whether existing evidence is also fit for comparative effectiveness research (CER. As a starting point, this paper therefore reflects on the evidence required for CER and the evidence gaps preventing decisions on market access and coverage. The paper then discusses challenges and potential barriers for applying a CER paradigm to PM, identifies common methodologies for designing clinical trials in PM, discusses various approaches for analyzing clinical trials to infer from population to individual level, and presents an example of a clinical trial in PM (The RxPONDER TRIAL demonstrating good practice. The paper concludes with a future perspective, including modeling approaches for evidence synthesis.Keywords: personalized

  14. rive gauche du fleuve Rimac

    International Development Research Centre (IDRC) Digital Library (Canada)

    vaux du projet, malgré le fait qu'il n'existe pas d'auto- rités locales propres à la rive gauche du fleuve Rímac, qui est plutôt desservie par diverses instances municipa- les (direction, sous-direction ou programme) ou la ges- tion décentralisée de Lima. La population ne peut donc établir une relation continue, soutenue et ...

  15. Perception de la gestion du paysage

    Directory of Open Access Journals (Sweden)

    Martin Coy

    2009-03-01

    Full Text Available Complex landscape management instruments based on a dynamic, innovative land-conservation paradigm and spatial zoning to provide for graded intensity of protection and human use are being implemented in the newer generation of biosphere reserves and biosphere parks. The multifunctionality of these exemplary landscapes with sustainable development is a great challenge; it also offers considerable potential for conflict. This paper intends to demonstrate the extent to which multifunctionality has been realised in the alpine Großes Walsertal Biosphere Park, and how the local population perceive the quality of their park five years after it was created. Landscape management efforts in the Großes Walsertal were monitored by accompanying regional-economic and perceptional studies, resulting in a discussion of required future actions.Des instruments complexes de gestion du paysage, fondés sur un paradigme dynamique et innovant de conservation ainsi que sur un zonage de l’espace visant à réguler la protection du territoire et son utilisation par l’homme, ont été mis en œuvre dans la dernière génération de réserves de biosphère et de parcs. La multifonctionnalité de ces paysages exemplaires du développement durable constitue un défi majeur, mais représente également une importante source de conflits. L’objectif de cet article est de démontrer dans quelle mesure la notion de multifonctionnalité a été appliquée à la réserve de biosphère alpine de Grosse Walsertal et d’évaluer comment la population locale perçoit la qualité de son parc, cinq ans après sa création. Les efforts de gestion du paysage dans la réserve de Grosse Walsertal ont été évalués par des études économiques régionales et par des enquêtes de perception, à l’origine d’un débat sur les actions futures à mettre en place.

  16. Simulation study of Rydberg atomic states interacting with electromagnetic radiation for use in future technological applications

    Science.gov (United States)

    Zou, Yi

    The present work involves the study of a simplified atomic system to gain better understanding of controlling and manipulating Rydberg-like systems. Detailed simulations of the classical hydrogen atom have been carried out using, first, the nonrelativistic Lorentz-Dirac classical equation of motion for a charged point particle under the action of a Coulombic binding force, plus applied radiation, then progressing to include the effects of the classical electromagnetic zero-point (ZP) radiation spectrum. This work has been carried out under the guide of the theory called stochastic electrodynamics (SED). Many applications involving atoms in excited Rydberg states can be developed, based on the work described here, to aid in carefully controlled thin film deposition, ion implantation, etching, and sputtering in micro and nanoelectronics, as well as optical instrumentation related applications, via applied electromagnetic fields. The improved simulation code for the long-term numerical integration of non-linear differential equations for tracking particles, should be helpful for a number of other closely related areas. Specifically, investigations into astronomy, including the Kepler problem treated in satellite and planetary orbit simulations in celestial mechanics, as well as problems in such areas as atomic and molecular dynamic studies, may well find benefit from the investigations here. As shown in the present study, very nonlinear behavior occurs for such Rydberg-like system, making a numerical study of the system nearly essential. Little of this work has been explored before in the literature. Resonances, rapid transitions, very long decay times, all influenced by applied radiation, are described and analyzed in detail here. Such results are expected to have significant bearing on recent experiments reported in the literature on "kicked Rydberg" atoms. Moreover, as reported here, the ZP field was included in very lengthy numerical simulations, resulting in a

  17. Palaeozoic stromatoporoid futures: A discussion of their taxonomy, mineralogy and applications in palaeoecology and palaeoenvironmental analysis

    Directory of Open Access Journals (Sweden)

    Steve Kershaw

    2013-04-01

    Full Text Available Palaeozoic stromatoporoids are calcified sponges common between Middle Ordovician and Late Devonian times in reefs and related facies. Taxonomic work is well known, but controversial because of conflict between classification schemes based on the calcareous skeleton versus spicules (which are almost completely lacking in Palaeozoic stromatoporoids; however, lower-level taxonomy (at genus-level of the calcareous skeleton is considered reliable to be applied in palaeobiological study. Knowledge of stromatoporoid ecology is poorly developed, such that comprehensive information is available for only a few case studies, in some Silurian and Devonian examples. Thus an overall understanding of stromatoporoid responses to environmental conditions has not yet been achieved, although stromatoporoids were likely able to deal with fine-grained sediment where they mostly occur. Many stromatoporoid genera have only certain growth forms, so future focus on the use of low-level taxonomy in ecological studies, by comprehensive sampling in high-resolution studies, may establish the relationships between stromatoporoids and their environments. Intergrown organisms and growth banding in stromatoporoids are aspects that have great potential in such work. Mineralogy of stromatoporoids remains poorly understood. Regardless of their apparent state of preservation (ranging from apparently well-preserved to complete loss of calcareous skeleton features all stromatoporoids are in fact substantially recrystallized. They underwent a peculiar diagenesis, whereby the calcareous skeleton and gallery cements of all stromatoporoids are overprinted by irregular elongated calcite crystals arranged normal to the growth laminations, most clearly visible in cross-polarized light. Stromatoporoids co-occur with mollusc shells that are always either fully recrystallized or dissolved (present as internal and external moulds; this difference means that while molluscs are likely under

  18. The Controlled Cortical Impact Model: Applications, Considerations for Researchers, & Future Directions

    Directory of Open Access Journals (Sweden)

    Nicole D. Osier

    2016-08-01

    Full Text Available The cControlled cortical impact model (CCI is a mechanical model of traumatic brain injury (TBI that was developed nearly 30 years ago with the goal of creating a testing platform to determine the biomechanical properties of brain tissue exposed to direct mechanical deformation. Initially used to model TBIs produced by automotive crashes, the CCI model rapidly transformed into a standardized technique to study TBI mechanisms and evaluate therapies. CCI is most commonly produced using a device that rapidly accelerates a rod to impact the surgically exposed cortical dural surface. The tip of the rod can be varied in size and geometry to accommodate scalability to difference species. Typically, the rod is actuated by a pneumatic piston or electro-mechanic actuator. With some limits, CCI devices can control the velocity, depth, duration, and site of impact. The CCI model produces morphologic and cerebrovascular injury responses that resemble certain aspects of human TBI. Commonly observed are graded histologic and axonal derangements, disruption of the blood-brain barrier, subdural and intra-parenchymal hematoma, edema, inflammation, and alterations in cerebral blood flow. The CCI model also produces neurobehavioral and cognitive impairments similar to those observed clinically. In contrast to other TBI models, the CCI device induces a significantly pronounced cortical contusion, but is limited in the extent to which it models the diffuse effects of TBI; a related limitation is that not all clinical TBI cases are characterized by a contusion. Another perceived limitation is that a non-clinically relevant craniotomy is performed. Biomechanically, this is irrelevant at the tissue level. However, craniotomies are not atraumatic and the effects of surgery should be controlled by including surgical sham control groups. CCI devices have also been successfully used to impact closed skulls to study mild and repetitive TBI. Future directions for CCI research

  19. Present status and future prospect of coated conductor development and its application in Japan

    Science.gov (United States)

    Shiohara, Y.; Yoshizumi, M.; Izumi, T.; Yamada, Y.

    2008-03-01

    The current national project on coated conductors using Y-system superconductors has been carried out over the project period (FY2003-FY2007). In this paper, the current status and the future prospect of this project are reviewed. The high performance tape development group, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting layers on PLD-CeO2/IBAD-GZO buffered substrates. A high product of Ic and L, higher than 112 166 A m, was achieved in a 368 m-304.8 A GdBCO tape whose Ic value is mostly above 350 A/cm in width. The performance under magnetic field was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO2. 61 m long GdBCO tape with ZrO2 doping showed a high Ic value of 220 A at self field and 30 A at 3 T. On the other hand, another group focusing on low production cost has worked on TFA-MOD and MOCVD processes. The extremely high Ic value of 735 A/cm-w was obtained in TFA-MOD films on PLD-CeO2/IBAD-GZO/Hastelloy substrate due to the effect of Ba-poor nominal composition. In efforts towards long tape production by the SWCC group, a 200 m long tape with a high Ic value of 200 A/cm-w was obtained using a batch-type furnace. The Ic × L value of this tape was 40 000 A m, which is the highest value in the world obtained by the TFA-MOD process. Based on the above achievements in coated conductor process development, two new additional goals were set in the project. One is the development of extremely low cost tape and the other is the development of the basic technologies for making electric power devices of cables, transformers, motors, current-limiters and cryocoolers. Some of the new investigations have already revealed marvellous results, such as a 15 kW motor, low AC loss coils, low AC loss cables, etc.

  20. Current status and future prospects of Japanese national project on coated conductor development and its applications

    Science.gov (United States)

    Shiohara, Y.; Yoshizumi, M.; Izumi, T.; Yamada, Y.

    2008-09-01

    Four years of the current five-year national project since 2003 for development of coated conductors using Y-system superconductors have passed and lots of remarkable results have been achieved. In this paper, the current status and the future prospect of this project are reviewed. The current national project comprises several groups of national laboratories, universities and private companies. The group of high performance tape development, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting tapes on the PLD-CeO 2/IBAD-GZO buffered substrates. The high product of Ic and L equal to 112,166 A m was achieved in the 368 m-304.8 A GdBCO tape whose Ic value is mostly above 350 A/cm-w. The performance under the magnetic fields was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO 2. About 61 m long GdBCO tape with ZrO 2 doping showed a high Ic value of 220 A at self field and 30 A at 3 T. On the other hand, the other group focusing on the low production cost has worked on processes of TFA-MOD and MOCVD, etc. The extremely high Ic value of 735 A/cm-w was attained in the TFA-MOD films on PLD-CeO 2/IBAD-GZO/Hastelloy C276 substrate by means of using the effect of Ba-poor nominal composition. In the efforts for long tape production, 200 m long tapes with high Ic values of 200 A/cm-w and 205 A/cm-w were obtained by MOD-YBCO/PLD-CeO 2/IBAD-GZO/Hastelloy C276 and PLD-HoBCO on buffered NiW substrate, respectively. The Ic × L value of the MOD-derived tape was 40,000 A m, which is the highest value in the world by the MOD process. Based on the above achievements on the coated conductor process development, two new additional goals were set in the project. One is the development for the extremely low cost tape and another is the development of the basic technologies for making the electric power devices including cables, transformers, motors, current-limiters and cryocoolers. Some of the new themes already revealed the

  1. Effectiveness and Future Prospects of Telemedicine/Remote Health Care Management Applications in Pakistan

    Directory of Open Access Journals (Sweden)

    SHAHID IQBAL

    2017-10-01

    Full Text Available Medical/Health care system is spraining in Pakistan because of innovative technology, activities and services as per their financial cost (position which is increasing day by day. This research is intended for the assessment of Telemedicine/Remote Health Care Management practices (system, which encompasses usability, acceptance and impact in public/private hospitals. To improve the existing remote health care/telemedicine practices in Pakistan by using EM (Engineering Management based approach. It has been widely and successfully implemented and is considered as a strategic and operational tool. In the 21stcentury due to the Technological advancements the mode of operation of service and business sector have been changed drastically. In the same way the health sectors activities also have been altered, new methods and techniques have also been devised for the treatment of the patients that were never even thought before. In the health sector Telemedicine/Remote Health Care Management is one of the development which was experienced lately. Telemedicine/Remote Health Careistaken exactly,? medicine at a distance?. Therefore, hypothetically, some procedures performed with medication which does not take place ?face-to-face? and ?in person? which can be considered as Telemedicine/Remote Health Care. In the industrialized world telemedicine is being used in full capacity to provide the health care services to remote and un-accessible areas. But Telemedicine/Remote Health Care Management is not very popular and admired in Pakistan; few applications are being functional presently.

  2. State of the Art and Future Trends in Grid Codes Applicable to Isolated Electrical Systems

    Directory of Open Access Journals (Sweden)

    Julia Merino

    2014-11-01

    Full Text Available Isolated electrical systems lack electrical interconnection to other networks and are usually placed in geographically isolated areas—mainly islands or locations in developing countries. Until recently, only diesel generators were able to assure a safe and reliable supply in exchange for very high costs for fuel transportation and system operation. Transmission system operators (TSOs are increasingly seeking to replace traditional energy models based on large groups of conventional generation units with mixed solutions where diesel groups are held as backup generation and important advantages are provided by renewable energy sources. The grid codes determine the technical requirements to be fulfilled by the generators connected in any electrical network, but regulations applied to isolated grids are more demanding. In technical literature it is rather easy to find and compare grid codes for interconnected electrical systems. However, the existing literature is incomplete and sparse regarding isolated grids. This paper aims to review the current state of isolated systems and grid codes applicable to them, specifying points of comparison and defining the guidelines to be followed by the upcoming regulations.

  3. PRESENT-DAY AND FUTURE APPLICATIONS OF NANOTECHNOLOGIES IN THE PRODUCTION OF BUILDING MATERIALS

    Directory of Open Access Journals (Sweden)

    Shuyskiy Anatoliy Ivanovich

    2012-12-01

    Full Text Available The authors have made an overview of the status of production of cement concrete using nanotechnologies. The authors also provide their analysis of domestic and foreign researches into the application of nanotechnologies in the field of building materials. The authors have picked out positive examples of introduction of nano-scale particles into the concrete mix. The process needs continuous monitoring for the composition and the mixing time to be adjustable. The findings have been solely made by local developers of nano-materials and technologies. The authors propose their method of cement consumption reduction through the introduction of nanoparticles and simultaneous grinding of cement. The authors provide a new procedure of treatment of materials that contemplates enhanced mixing processes accompanied by simultaneous grinding of materials and their exposure to the electromagnetic treatment. The experiments completed by the team of authors have proven the efficiency of a combination of two nanotechnologies within one process, including the treatment of wet cement at the final grinding stage of processing to ensure specific cement properties for a specific surface area of 8,000 cm2/g, and the introduction of nano-scale particles into the process of manufacturing of cement compositions. The use of carbon nanotubes in the process of manufacturing of cement concrete can improve its physical and mechanical properties and reduce the cement consumption rate while maintaining the design strength of concrete.

  4. Clinical applications of urinary cell-free DNA in cancer: current insights and promising future.

    Science.gov (United States)

    Lu, Tian; Li, Jinming

    2017-01-01

    Liquid biopsy is gaining significant attention as a tool for unveiling the molecular landscape of tumor and holds great promise for individualized medicine for cancer. Cell-free DNA serves as an extremely important component of liquid biopsy for cancer, and cell-free DNA in urine is even promising due to the remarkable advantage of urine as an ultra-noninvasive sample source over tissue and blood. Compared with the widely studied cell-free DNA in blood, less is known about the role of urinary cell-free DNA. Urinary cell-free DNA has the ability to give comprehensive and crucial information on cancer as it carries genetic messages from cells shedding directly into urine as well as transporting from circulation. As an indispensable component of liquid biopsy, urinary cell-free DNA is believed to have the potential of being a useful and ultra-noninvasive tool for cancer screening, diagnosis, prognosis, and monitoring of cancer progression and therapeutic effect. In this review, we provide the current insights into the clinical applications of urinary cell-free DNA in cancer. We also introduce the basic biological significance and some technical issues in the detection of urinary cell-free DNA.

  5. Cooperation and Competition with Hyperscanning Methods: Review and Future Application to Emotion Domain

    Directory of Open Access Journals (Sweden)

    Michela Balconi

    2017-09-01

    Full Text Available Cooperation and competition, as two common and opposite examples of interpersonal dynamics, are thought to be reflected by different cognitive, neural, and behavioral patterns. According to the conventional approach, they have been explored by measuring subjects' reactions during individual performance or turn-based interactions in artificial settings, that don't allow on-line, ecological enactment of real-life social exchange. Considering the importance of these factors, and accounting for the complexity of such phenomena, the hyperscanning approach emerged as a multi-subject paradigm since it allows the simultaneous recording of the brain activity from multiple participants interacting. In this view, the present paper aimed at reviewing the most significant work about cooperation and competition by EEG hyperscanning technique, which proved to be a promising tool in capturing the sudden course of social interactions. In detail, the review will consider and group different experimental tasks that have been developed so far: (1 paradigms that used rhythm, music and motor synchronization; (2 card tasks taken from the Game Theory; (3 computerized tasks; and (4 possible real-life applications. Finally, although highlighting the potential contribution of such approach, some important limitations about these paradigms will be elucidated, with a specific focus on the emotional domain.

  6. An Overview of Small Unmanned Aerial Vehicles for Air Quality Measurements: Present Applications and Future Prospectives

    Directory of Open Access Journals (Sweden)

    Tommaso Francesco Villa

    2016-07-01

    Full Text Available Assessment of air quality has been traditionally conducted by ground based monitoring, and more recently by manned aircrafts and satellites. However, performing fast, comprehensive data collection near pollution sources is not always feasible due to the complexity of sites, moving sources or physical barriers. Small Unmanned Aerial Vehicles (UAVs equipped with different sensors have been introduced for in-situ air quality monitoring, as they can offer new approaches and research opportunities in air pollution and emission monitoring, as well as for studying atmospheric trends, such as climate change, while ensuring urban and industrial air safety. The aims of this review were to: (1 compile information on the use of UAVs for air quality studies; and (2 assess their benefits and range of applications. An extensive literature review was conducted using three bibliographic databases (Scopus, Web of Knowledge, Google Scholar and a total of 60 papers was found. This relatively small number of papers implies that the field is still in its early stages of development. We concluded that, while the potential of UAVs for air quality research has been established, several challenges still need to be addressed, including: the flight endurance, payload capacity, sensor dimensions/accuracy, and sensitivity. However, the challenges are not simply technological, in fact, policy and regulations, which differ between countries, represent the greatest challenge to facilitating the wider use of UAVs in atmospheric research.

  7. Laser Induced Breakdown Spectroscopy in archeometry: A review of its application and future perspectives

    Science.gov (United States)

    Spizzichino, Valeria; Fantoni, Roberta

    2014-09-01

    Laser Induced Breakdown Spectroscopy (LIBS) in the last decades has been more and more applied to the field of Cultural Heritage with great results obtained either alone or in combination with complementary laser techniques. Its ability to analyze, with a minimal loss, different kinds of materials in laboratory, in situ and even in hostile environments has been highly appreciated. The main aim of this paper is to present a review of LIBS applications in the interdisciplinary field of archeometry. The LIBS technique is shortly described both from a theoretical and practical point of view, discussing the instrumental setup, also in comparison with typical features of laser induced fluorescence (LIF) and Raman spectroscopy apparata. The complementary with multivariate analysis, a method that can help in reducing data set dimensions and in pulling out effective information, is stressed. In particular the role of LIBS in Cultural Heritage material characterization, recognition of fakes and indirect dating is described, reporting general considerations and case studies on metal alloys, mural paintings, decorated ceramics, glasses, stones and gems.

  8. Future health applications of genomics: priorities for communication, behavioral, and social sciences research.

    Science.gov (United States)

    McBride, Colleen M; Bowen, Deborah; Brody, Lawrence C; Condit, Celeste M; Croyle, Robert T; Gwinn, Marta; Khoury, Muin J; Koehly, Laura M; Korf, Bruce R; Marteau, Theresa M; McLeroy, Kenneth; Patrick, Kevin; Valente, Thomas W

    2010-05-01

    Despite the quickening momentum of genomic discovery, the communication, behavioral, and social sciences research needed for translating this discovery into public health applications has lagged behind. The National Human Genome Research Institute held a 2-day workshop in October 2008 convening an interdisciplinary group of scientists to recommend forward-looking priorities for translational research. This research agenda would be designed to redress the top three risk factors (tobacco use, poor diet, and physical inactivity) that contribute to the four major chronic diseases (heart disease, type 2 diabetes, lung disease, and many cancers) and account for half of all deaths worldwide. Three priority research areas were identified: (1) improving the public's genetic literacy in order to enhance consumer skills; (2) gauging whether genomic information improves risk communication and adoption of healthier behaviors more than current approaches; and (3) exploring whether genomic discovery in concert with emerging technologies can elucidate new behavioral intervention targets. Important crosscutting themes also were identified, including the need to: (1) anticipate directions of genomic discovery; (2) take an agnostic scientific perspective in framing research questions asking whether genomic discovery adds value to other health promotion efforts; and (3) consider multiple levels of influence and systems that contribute to important public health problems. The priorities and themes offer a framework for a variety of stakeholders, including those who develop priorities for research funding, interdisciplinary teams engaged in genomics research, and policymakers grappling with how to use the products born of genomics research to address public health challenges. 2010. Published by Elsevier Inc.

  9. An Overview of Small Unmanned Aerial Vehicles for Air Quality Measurements: Present Applications and Future Prospectives.

    Science.gov (United States)

    Villa, Tommaso Francesco; Gonzalez, Felipe; Miljievic, Branka; Ristovski, Zoran D; Morawska, Lidia

    2016-07-12

    Assessment of air quality has been traditionally conducted by ground based monitoring, and more recently by manned aircrafts and satellites. However, performing fast, comprehensive data collection near pollution sources is not always feasible due to the complexity of sites, moving sources or physical barriers. Small Unmanned Aerial Vehicles (UAVs) equipped with different sensors have been introduced for in-situ air quality monitoring, as they can offer new approaches and research opportunities in air pollution and emission monitoring, as well as for studying atmospheric trends, such as climate change, while ensuring urban and industrial air safety. The aims of this review were to: (1) compile information on the use of UAVs for air quality studies; and (2) assess their benefits and range of applications. An extensive literature review was conducted using three bibliographic databases (Scopus, Web of Knowledge, Google Scholar) and a total of 60 papers was found. This relatively small number of papers implies that the field is still in its early stages of development. We concluded that, while the potential of UAVs for air quality research has been established, several challenges still need to be addressed, including: the flight endurance, payload capacity, sensor dimensions/accuracy, and sensitivity. However, the challenges are not simply technological, in fact, policy and regulations, which differ between countries, represent the greatest challenge to facilitating the wider use of UAVs in atmospheric research.

  10. An Overview of Small Unmanned Aerial Vehicles for Air Quality Measurements: Present Applications and Future Prospectives

    Science.gov (United States)

    Villa, Tommaso Francesco; Gonzalez, Felipe; Miljievic, Branka; Ristovski, Zoran D.; Morawska, Lidia

    2016-01-01

    Assessment of air quality has been traditionally conducted by ground based monitoring, and more recently by manned aircrafts and satellites. However, performing fast, comprehensive data collection near pollution sources is not always feasible due to the complexity of sites, moving sources or physical barriers. Small Unmanned Aerial Vehicles (UAVs) equipped with different sensors have been introduced for in-situ air quality monitoring, as they can offer new approaches and research opportunities in air pollution and emission monitoring, as well as for studying atmospheric trends, such as climate change, while ensuring urban and industrial air safety. The aims of this review were to: (1) compile information on the use of UAVs for air quality studies; and (2) assess their benefits and range of applications. An extensive literature review was conducted using three bibliographic databases (Scopus, Web of Knowledge, Google Scholar) and a total of 60 papers was found. This relatively small number of papers implies that the field is still in its early stages of development. We concluded that, while the potential of UAVs for air quality research has been established, several challenges still need to be addressed, including: the flight endurance, payload capacity, sensor dimensions/accuracy, and sensitivity. However, the challenges are not simply technological, in fact, policy and regulations, which differ between countries, represent the greatest challenge to facilitating the wider use of UAVs in atmospheric research. PMID:27420065

  11. Marine current energy devices: Current status and possible future applications in Ireland

    Energy Technology Data Exchange (ETDEWEB)

    Rourke, Fergal O.; Boyle, Fergal; Reynolds, Anthony [Department of Mechanical Engineering, Dublin Institute of Technology, Bolton Street, Dublin 1 (Ireland)

    2010-04-15

    There is a growing demand for the use of renewable energy technologies to generate electricity due to concerns over climate change. The oceans provide a huge potential resource of energy. Energy extraction using marine current energy devices (MCEDs) offers a sustainable alternative to conventional sources and a predictable alternative to other renewable energy technologies. A MCED utilises the kinetic energy of the tides as opposed to the potential energy which is utilised by a tidal barrage. Over the past decade MCEDs have become an increasingly popular method of energy extraction. However, marine current energy technology is still not economically viable on a large scale due to its current stage of development. Ireland has an excellent marine current energy resource as it is an island nation and experiences excellent marine current flows. This paper reviews marine current energy devices, including a detailed up-to-date description of the current status of development. Issues such as network integration, economics, and environmental implications are addressed as well as the application and costs of MCEDs in Ireland. (author)

  12. Advances in defining a closed brayton conversion system for future ARIANE 5 space nuclear power applications

    International Nuclear Information System (INIS)

    Tilliette, Z.P.

    1986-06-01

    The present European ARIANE space program will expand into the large ARIANE 5 launch vehicle from 1995. It is assumed that important associated missions would require the generation of 200 kWe or more in space during several years at the very beginning of the next century. It is the reason why, in 1983, the French C.N.E.S. (Centre National d'Etudes Spatiales) and C.E.A. (Commissariat a l'Energie Atomique) have initiated preliminary studies of a space nuclear power system. The currently selected conversion system is a closed Brayton cycle. Reasons for this choice are given: high efficiency of a dynamic system; monophasic, inert working fluid; extensive turbomachinery experience, etc... A key aspect of the project is the adaptation to the heat rejection conditions, namely to the radiator geometry which depends upon the dimensions of the ARIANE 5 spacecraft. In addition to usual concepts already studied for space applications, another cycle arrangement is being investigated which could offer satisfactory compromises among many considerations, increase the efficiency of the system and make it more attractive as far as the specific mass (kg/kWe), the specific radiator area (m 2 /kWe) and various technological aspects are concerned. Comparative details are presented

  13. Biochar-based functional materials in the purification of agricultural wastewater: Fabrication, application and future research needs.

    Science.gov (United States)

    Wei, Dongning; Li, Bingyu; Huang, Hongli; Luo, Lin; Zhang, Jiachao; Yang, Yuan; Guo, Jiajun; Tang, Lin; Zeng, Guangming; Zhou, Yaoyu

    2018-04-01

    Nowadays, agricultural contamination is becoming more and more serious due to the rapid growth of agricultural industry, which discharged antibiotics, pesticides or toxic metals into farmlands. A large number of researchers have applied biochar-based functional materials to the treatment of agricultural wastewater contamination. Meanwhile, biochar has also proved to be a very promising and effective technology in water purification field due to its various beneficial properties (e.g., cost effective, high specific surface area, and surface reactive groups). The focus of this review is to highlight the fabrication methods and application of biochar-based functional materials with the removal of different agricultural contaminants, and discuss the underlying mechanisms. However, the application of biochar-based functional materials is currently under its infancy, with the main hindrance is identified as the gap between laboratory scale and field application, immaturity of engineered biochar production technologies, and lack of quality standards. In order to fill these knowledge gaps, more efforts should be made to pay for the relevant research in future studies. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Analyse biomécanique et simulation du mouvement de préhension : application aux mouvements altérés

    OpenAIRE

    Rezzoug , Nasser

    2014-01-01

    Prehension and upper-limb movements are of paramount importance in the repertoire of goal directed movements. As such, they are associated to a wide range of applications in biomechanics, rehabilitation, computer assisted ergonomics, robotics or animation. Moreover, their study and simulation in different populations such as young, middle aged, and elderly people or persons that suffer from a pathology allow to gain insight into human movement control and motor redundancy. The presented resea...

  15. Advanced simulation capability for environmental management - current status and future applications

    International Nuclear Information System (INIS)

    Freshley, Mark; Scheibe, Timothy; Robinson, Bruce; Moulton, J. David; Dixon, Paul; Marble, Justin; Gerdes, Kurt; Stockton, Tom; Seitz, Roger; Black, Paul

    2013-01-01

    The U.S. Department of Energy (US DOE) Office of Environmental Management (EM), Office of Soil and Groundwater (EM-12), is supporting development of the Advanced Simulation Capability for Environmental Management (ASCEM). ASCEM is a state-of-the-art scientific tool and approach that is currently aimed at understanding and predicting contaminant fate and transport in natural and engineered systems. ASCEM is a modular and open source high-performance computing tool. It will be used to facilitate integrated approaches to modeling and site characterization, and provide robust and standardized assessments of performance and risk for EM cleanup and closure activities. The ASCEM project continues to make significant progress in development of capabilities, with current emphasis on integration of capabilities in FY12. Capability development is occurring for both the Platform and Integrated Tool-sets and High-Performance Computing (HPC) multi-process simulator. The Platform capabilities provide the user interface and tools for end-to-end model development, starting with definition of the conceptual model, management of data for model input, model calibration and uncertainty analysis, and processing of model output, including visualization. The HPC capabilities target increased functionality of process model representations, tool-sets for interaction with Platform, and verification and model confidence testing. The integration of the Platform and HPC capabilities were tested and evaluated for EM applications in a set of demonstrations as part of Site Applications Thrust Area activities in 2012. The current maturity of the ASCEM computational and analysis capabilities has afforded the opportunity for collaborative efforts to develop decision analysis tools to support and optimize radioactive waste disposal. Recent advances in computerized decision analysis frameworks provide the perfect opportunity to bring this capability into ASCEM. This will allow radioactive waste

  16. Computational intelligence in gait research: a perspective on current applications and future challenges.

    Science.gov (United States)

    Lai, Daniel T H; Begg, Rezaul K; Palaniswami, Marimuthu

    2009-09-01

    Our mobility is an important daily requirement so much so that any disruption to it severely degrades our perceived quality of life. Studies in gait and human movement sciences, therefore, play a significant role in maintaining the well-being of our mobility. Current gait analysis involves numerous interdependent gait parameters that are difficult to adequately interpret due to the large volume of recorded data and lengthy assessment times in gait laboratories. A proposed solution to these problems is computational intelligence (CI), which is an emerging paradigm in biomedical engineering most notably in pathology detection and prosthesis design. The integration of CI technology in gait systems facilitates studies in disorders caused by lower limb defects, cerebral disorders, and aging effects by learning data relationships through a combination of signal processing and machine learning techniques. Learning paradigms, such as supervised learning, unsupervised learning, and fuzzy and evolutionary algorithms, provide advanced modeling capabilities for biomechanical systems that in the past have relied heavily on statistical analysis. CI offers the ability to investigate nonlinear data relationships, enhance data interpretation, design more efficient diagnostic methods, and extrapolate model functionality. These are envisioned to result in more cost-effective, efficient, and easy-to-use systems, which would address global shortages in medical personnel and rising medical costs. This paper surveys current signal processing and CI methodologies followed by gait applications ranging from normal gait studies and disorder detection to artificial gait simulation. We review recent systems focusing on the existing challenges and issues involved in making them successful. We also examine new research in sensor technologies for gait that could be combined with these intelligent systems to develop more effective healthcare solutions.

  17. The South African National Vegetation Database: History, development, applications, problems and future

    Directory of Open Access Journals (Sweden)

    Leslie W. Powrie

    2012-01-01

    Full Text Available Southern Africa has been recognised as one of the most interesting and important areas of the world from an ecological and evolutionary point of view. The establishment and development of the National Vegetation Database (NVD of South Africa enabled South Africa to contribute to environmental planning and conservation management in this floristically unique region. In this paper, we aim to provide an update on the development of the NVD since it was last described, near its inception, more than a decade ago. The NVD was developed using the Turboveg software environment, and currently comprises 46 697 vegetation plots (relevés sharing 11 690 plant taxa and containing 968 943 species occurrence records. The NVD was primarily founded to serve vegetation classification and mapping goals but soon became recognised as an important tool in conservation assessment and target setting. The NVD has directly helped produce the National Vegetation Map, National Forest Type Classification, South African National Biodiversity Assessment and Forest Type Conservation Assessment. With further development of the NVD and more consistent handling of the legacy data (old data sets, the current limitations regarding certain types of application of the data should be significantly reduced. However, the use of the current NVD in multidisciplinary research has certainly not been fully explored. With the availability of new pools of well-trained vegetation surveyors, the NVD will continue to be purpose driven and serve the needs of biological survey in pursuit of sustainable use of the vegetation and flora resources of the southern African subcontinent.

  18. Recycle of scrap plutonium-238 oxide fuel to support future radioisotope applications

    International Nuclear Information System (INIS)

    Schulte, L.D.; Espinoza, J.M.; Ramsey, K.B.; Rinehart, G.H.; Silver, G.L.; Purdy, G.M.; Jarvinen, G.D.

    1997-11-01

    The Nuclear Materials Technology (NMT) Division of Los Alamos National Laboratory has initiated a development program to recover and purify plutonium-238 oxide from impure feed sources in a glove box environment. A glove box line has been designed and a chemistry flowsheet developed to perform this recovery task at large scale. The initial demonstration effort focused on purification of 238 PuO 2 fuel by HNO 3 /HF dissolution, followed by plutonium(III) oxalate precipitation and calcination to an oxide. Decontamination factors for most impurities of concern in the fuel were very good, producing 238 PuO 2 fuel significantly better in purity than specified by General Purpose Heat Source (GPHS) fuel powder specifications. The results are encouraging for recycle of relatively impure plutonium-238 oxide and scrap residue items into fuel for useful applications. A sufficient quantity of purified 238 PuO 2 fuel was recovered from the process to allow fabrication of a GPHS unit for testing. The high specific activity of plutonium-238 magnifies the consequences and concerns of radioactive waste generation. This work places an emphasis on development of waste minimization technologies to complement the aqueous processing operation. Results from experiments allowing more time for neutralized solutions of plutonium-238 to precipitate resulted in decontamination to about 1 millicurie/L. Combining ultrafiltration treatment with addition of a water-soluble polymer designed to coordinate Pu, allowed solutions to be decontaminated to about 1 microcurie/L. Efforts continue to develop a capability for efficient, safe, cost-effective, and environmentally acceptable methods to recover and purify 238 PuO 2 fuel

  19. Recycle of scrap plutonium-238 oxide fuel to support future radioisotope applications

    Energy Technology Data Exchange (ETDEWEB)

    Schulte, L.D.; Espinoza, J.M.; Ramsey, K.B.; Rinehart, G.H.; Silver, G.L.; Purdy, G.M.; Jarvinen, G.D.

    1997-11-01

    The Nuclear Materials Technology (NMT) Division of Los Alamos National Laboratory has initiated a development program to recover and purify plutonium-238 oxide from impure feed sources in a glove box environment. A glove box line has been designed and a chemistry flowsheet developed to perform this recovery task at large scale. The initial demonstration effort focused on purification of {sup 238}PuO{sub 2} fuel by HNO{sub 3}/HF dissolution, followed by plutonium(III) oxalate precipitation and calcination to an oxide. Decontamination factors for most impurities of concern in the fuel were very good, producing {sup 238}PuO{sub 2} fuel significantly better in purity than specified by General Purpose Heat Source (GPHS) fuel powder specifications. The results are encouraging for recycle of relatively impure plutonium-238 oxide and scrap residue items into fuel for useful applications. A sufficient quantity of purified {sup 238}PuO{sub 2} fuel was recovered from the process to allow fabrication of a GPHS unit for testing. The high specific activity of plutonium-238 magnifies the consequences and concerns of radioactive waste generation. This work places an emphasis on development of waste minimization technologies to complement the aqueous processing operation. Results from experiments allowing more time for neutralized solutions of plutonium-238 to precipitate resulted in decontamination to about 1 millicurie/L. Combining ultrafiltration treatment with addition of a water-soluble polymer designed to coordinate Pu, allowed solutions to be decontaminated to about 1 microcurie/L. Efforts continue to develop a capability for efficient, safe, cost-effective, and environmentally acceptable methods to recover and purify {sup 238}PuO{sub 2} fuel.

  20. Biomedical engineering strategies for peripheral nerve repair: surgical applications, state of the art, and future challenges.

    Science.gov (United States)

    Pfister, Bryan J; Gordon, Tessa; Loverde, Joseph R; Kochar, Arshneel S; Mackinnon, Susan E; Cullen, D Kacy

    2011-01-01

    Damage to the peripheral nervous system is surprisingly common and occurs primarily from trauma or a complication of surgery. Although recovery of nerve function occurs in many mild injuries, outcomes are often unsatisfactory following severe trauma. Nerve repair and regeneration presents unique clinical challenges and opportunities, and substantial contributions can be made through the informed application of biomedical engineering strategies. This article reviews the clinical presentations and classification of nerve injuries, in addition to the state of the art for surgical decision-making and repair strategies. This discussion presents specific challenges that must be addressed to realistically improve the treatment of nerve injuries and promote widespread recovery. In particular, nerve defects a few centimeters in length use a sensory nerve autograft as the standard technique; however, this approach is limited by the availability of donor nerve and comorbidity associated with additional surgery. Moreover, we currently have an inadequate ability to noninvasively assess the degree of nerve injury and to track axonal regeneration. As a result, wait-and-see surgical decisions can lead to undesirable and less successful "delayed" repair procedures. In this fight for time, degeneration of the distal nerve support structure and target progresses, ultimately blunting complete functional recovery. Thus, the most pressing challenges in peripheral nerve repair include the development of tissue-engineered nerve grafts that match or exceed the performance of autografts, the ability to noninvasively assess nerve damage and track axonal regeneration, and approaches to maintain the efficacy of the distal pathway and targets during the regenerative process. Biomedical engineering strategies can address these issues to substantially contribute at both the basic and applied levels, improving surgical management and functional recovery following severe peripheral nerve injury.