Comparative evaluation of cerebral aneurysms with selective arterially enhanced CT and DSA

International Nuclear Information System (INIS)

Vanderschelden, P.; Flandroy, P.; Dondelinger, R.F.; Martin, D.; Lenelle, J.

1998-01-01

The purpose of our study was to compare selective arterially enhanced spiral computed tomographs (ACT) with digital subtraction angiographies (DSA) in the presurgical assessment of cerebral aneurysms. A total of 24 aneurysms in 18 patients were explored in a prospective study by ACT and DSA, using an interactive combined CT-angiography suite. Dimensions of the aneurysm, its relation to the parent vessel, and the aneurysmal index were defined on DSA and on surface-shaded display of 3D reformatted images obtained from ACT. Results were correlated with surgical findings. Three aneurysms suspected on DSA were not confirmed by ACT. One fusiform aneurysm suspected on DSA corresponded to a sacciform aneurysm on ACT. Surgical findings confirmed 20 sacciform aneurysms. The aneurysmal index could be measured in all 20 cases of sacciform aneurysms on ACT and could not be determined with confidence in 55 % of the cases on DSA. DSA and ACT gave identical results in 35 % of cases. In 10 %, the index measured by ACT was superior to that determined by DSA for aneurysms which had a diameter of less than 3 mm. In conclusion, the combination of DSA and ACT improved the results of DSA alone. ACT is a reliable method to measure the aneurysmal index in aneurysms with a diameter superior to 3 mm. (orig.)

[Design and development of the DSA digital subtraction workstation].

Science.gov (United States)

Peng, Wen-Xian; Peng, Tian-Zhou; Xia, Shun-Ren; Jin, Guang-Bo

2008-05-01

According to the patient examination criterion and the demands of all related departments, the DSA digital subtraction workstation has been successfully designed and is introduced in this paper by analyzing the characteristic of video source of DSA which was manufactured by GE Company and has no DICOM standard interface. The workstation includes images-capturing gateway and post-processing software. With the developed workstation, all images from this early DSA equipment are transformed into DICOM format and then are shared in different machines.

Preoperative imaging in 78 living kidney donors using CE-MRA and DSA; Donor-Evaluation vor Lebendnierenspende: Vergleich von CE-MRA und DSA an 78 Patienten

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Lemke, U.; Taupitz, M.; Hamm, B.; Kroencke, T.J. [Inst. fuer Radiologie, Charite - Universitaetsmedizin Berlin (Germany); Kluener, C. [Inst. fuer Radiologie und Neuroradiologie, Evangelisches Krankenhaus Oldenburg (Germany); Giessing, M.; Schoenberger, B. [Urologische Klinik und Poliklinik, Charite - Universitaetsmedizin Berlin (Germany)

2008-01-15

Purpose: to evaluate contrast-enhanced 3D magnetic resonance angiography (CE-MRA) and digital subtraction angiography (DSA) in comparison with the intraoperative findings in living kidney donors. Materials and methods: a total of 156 kidneys in 78 potential kidney donors were prospectively examined using CE-MRA (0.2 mmol Gd/kg, voxel size 1.3 x 0.8 x 2.0) and DSA. Two experienced radiologists assessed the images in consensus regarding the renal vascular anatomy and variants. The results for the 67 candidates accepted for donation were compared to the intraoperative findings. In the other kidneys not accepted for donor nephrectomy, MRA and DSA were compared with each other. Results: nineteen arterial variants were identified intraoperatively, of which 11 (58%) were also detected by preoperative CE-MRA and 10 (53%) by preoperative DSA. Of the 10 venous variants found intraoperatively, CE-MRA detected 8 (80%) and DSA 3 (30%). The agreement (kappa test) between MRI and DSA for all 156 evaluated kidneys was 0.7 for arterial variants (McNemar p = 0.12) and 0.3 for venous variants (McNemar p = 0.01). The preoperative choice of kidney (right or left) made on the basis of the renal vascular anatomy seen on CE-MRA and DSA differed in 22% of the 78 potential donors (McNemar P = 0.3). (orig.)

The DSA findings and interventional therapy of hepatic alveolar echinococcus

International Nuclear Information System (INIS)

Ren Weixin; Xiao Xiangsheng; Chen Peng; Ma Jun

2004-01-01

Objective: To analyse the DSA findings of hepatic alveolar echinococcus (HAE) and evaluate the feasibility of the interventional therapy. Methods: Eight patients with HAE were all examined by DSA, CT and lab test. Three of them were performed the transcatheter arterial embolization by iodized oil. All of them were confirmed by surgical operation and followed-up for three months. Results: The DSA findings of HAE included hepatic arterial curling and enlargement with hypertrophied circled encircling as typical 'handed ball'. Eight cases presented the ring stain during the capillary stage. After embolization, the retention of iodized oil was revealed by DSA in 3 cases. CT three months later showed fine iodized oil retention and the enlarged necrosis. Ischemic necrosis around the lesion and the cut margins were clearly seen in operation biopsy. Conclusions: HAE possesses special DSA findings and interventional therapy is a new therapeutic method of choice. (authors)

Intra-arterial DSA of the mesenterico-spleno-portal vessels

Energy Technology Data Exchange (ETDEWEB)

Busch, H P; Hoevels, J; Prager, P; Strauss, L

1985-01-01

The article examines the application of i.a. DSA for the visualization of mesenterico-spleno-portal veins. Indications are portal hypertension and resectability assessment in pancreas tumours. Compared with conventional angiography, i.a. DSA yields a better demonstration of the splanchnic veins in about 50% of the cases. Advantages of i.a. DSA involve good-quality vessel visualization along with a reduction of examination time and cost. Its disadvantages are low-grade local resolution and strong dependence of picture quality on the patients' cooperation.

In vitro and clinical evaluation of DSA in acute gastrointestinal bleeding

International Nuclear Information System (INIS)

Rees, C.R.; Palmaz, J.C.; Alvarado, R.; Tyrrel, R.; Ciaravino, V.; Register, T.; Reuter, S.R.

1987-01-01

In an in vitro model of gastrointestinal (GI) bleeding, digital subtraction angiography (DSA) was found to be more accurate, more sensitive, and equally specific in the detection of extravasation compared to conventional screen-film angiography /sub chi//sup 2/, P < .05), DSA was used in the diagnosis and/or therapeutic management of 35 patients with GI bleeding (in the upper tract in 30, in the lower tract in five). When DSA results were negative (13 cases), results of conventional angiography were also negative. Upper GI bleeding episodes could be managed solely with DSA, which shortened examination times by 20% - 35%. The usefulness of DSA in lower GI bleeding was limited in the authors' series by a 9-inch image intensifier and misregistration caused by bowel motion

Pre-transplant soluble CD30 in combination with total DSA but not pre-transplant C1q-DSA predicts antibody-mediated graft loss in presensitized high-risk kidney transplant recipients.

Science.gov (United States)

Schaefer, S M; Süsal, C; Opelz, G; Döhler, B; Becker, L E; Klein, K; Sickmüller, S; Waldherr, R; Macher-Goeppinger, S; Schemmer, P; Beimler, J; Zeier, M; Morath, C

2016-02-01

Presensitized kidney transplant recipients are at high-risk for early antibody-mediated rejection. We studied the impact of pre- and post-transplant donor-specific human leukocyte antigen (HLA) antibodies (DSA) and T-cell-activation on the occurrence of antibody-mediated rejection episodes (AMR) and graft loss (AMR-GL) in a unique cohort of 80 desensitized high-risk kidney transplant recipients. Patients with pre-transplant DSA demonstrated more AMR episodes than patients without DSA, but did not show a significantly increased rate of AMR-GL. The rates of AMR and AMR-GL were not significantly increased in patients with complement split product (C1q)-binding pre-transplant DSA. Pre-transplant C1q-DSA became undetectable post-transplant in 11 of 13 (85%) patients; 2 (18%) of these 11 patients showed AMR but no AMR-GL. In contrast, the post-transplant presence of C1q-DSA was associated with significantly higher rates of AMR (86 vs 33 vs 0%; P transplant DSA without C1q-binding or the absence of DSA. Patients with both pre-transplant DSA and evidence of pre-transplant T-cell-activation as indicated by soluble CD30-positivity showed a significantly increased risk for AMR-GL [HR = 11.1, 95% confidence interval (CI) = 1.68-73.4; log-rank P = 0.013]. In these high-risk patients, AMR-GL was associated with total DSA in combination with T-cell-activation pre-transplant, and de novo or persistent C1q-binding DSA post-transplant. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Comparative analysis of CT and DSA in traumatic splenic salvage

International Nuclear Information System (INIS)

Liu Tie; Mao Xinfeng; Pan Feng

2005-01-01

Objective: To explore the better diagnostic method for acute splenic artery injury through comparative analysis of CT and DSA. Methods: Fifty-seven patients with acute splenic injury were examined by CT and DSA, treated with splenic arterial embolization and then undertook follow up. Results: CT examination possessed higher sensitivity and accuracy than DSA in demonstrating splenic parenchymal laceration, intrasplenic hematoma, subcapsular hematoma, rupture of splenic capsule and combined injury of intra-abdominal organs, especially in localizing splenic laceration. And there was a high significant difference statistically between the two kinds of examination (χ 2 =10.71, P 2 =12.57, P<0.005). Conclusions: CT and DSA are complementary in the diagnosis of splenic injury. After CT confirmation of splenic injury and the patient vital signs being stable, DSA should be referred to as soon as possible for further detail information as well as for possible interventional embolization and reduction of surgical complications. (authors)

Fundamental study of DSA images using gadolinium contrast agent

International Nuclear Information System (INIS)

Nagashima, Hiroyuki; Shiraishi, Akihisa; Igarashi, Hitoshi; Sakamoto, Hajime; Sano, Yoshitomo

2002-01-01

Most contrast agents used in digital subtraction angiography (DSA) are non-ionic iodinated contrast agents, which can cause severe side effects in patients with contraindications for iodine or allergic reactions to iodine. Therefore, DSA examinations using carbon dioxide gas or examinations done by magnetic resonance imaging (MRI) and ultrasound (US) were carried out in these patients. However, none of these examinations provided mages as clear as those of DSA with an iodinated contrast agent. We experienced DSA examination using a gadolinium contrast agent in a patient contraindicated for iodine. The patient had undergone MRI examination with a gadolinium contrast agent previously without side effects. The characteristics of gadolinium and the iodinated contrast agent were compared, and the DSA images obtained clinically using these media were also evaluated. The signal-to-noise (SN) ratio of the gadolinium contrast agent was the highest at tube voltages of 70 to 80 kilovolts and improved slightly when the image intensifier (I.I.) entrance dose was greater than 300 μR (77.4 nC/kg). The dilution ratios of five iodinated contrast agents showed the same S/N value as the undiluted gadolinium contrast agent. Clinically, the images obtained showed a slight decrease in contrast but provided the data necessary to make a diagnosis and made it possible to obtain interventional radiology (IVR) without any side effects. DSA examinations using a gadolinium contrast agent have some benefit with low risk and are thought to be useful for patients contraindicated for iodine. (author)

Peripheral occlusive vascular disease: Diagnostic performance of MRA and DSA

International Nuclear Information System (INIS)

Krug, B.; Kugel, H.; Harnischmacher, U.; Heindel, W.; Altenburg, A.; Fischbach, R.; Schmidt, R.

1995-01-01

In 59 patients with arterial flow disturbances 2-D inflow sequence of the abdominal and lower leg arteries were prospectively obtained on a 1.5 T MR-imager and were compared with additional DSA examinations. Supplementary Phase Contraste RSE ('Rapid Sequential Excitation') sequences were carried out in 29 patients. MRA and DSA angiograms were evaluated in random order by 4 readers using a questionnaire. The assessment of image quality were evaluated by variance analysis. Diagnostic performance of MRA and DSA was assessed by comparison of the readers' diagnostic assessments with reference diagnoses established by a radiologist and a vascular surgeon with full knowledge of all data concerning a patient. Image quality of inflow MRA was considered inferior to i.a. DSA (p [de

Coregistration of three dimensional DSA and MR angiography in neuronavigation for neurosurgery

International Nuclear Information System (INIS)

Tang Weijun; Jin Yi; Li Ke; Feng Xiaoyuan; Hong Yong

2007-01-01

Objective: To assess the accuracy of neuronavigation of 3D DSA and to evaluate the feasibility of 3D DSA neuronavigational neurosurgery through the coregistration of 3D DSA and MRI(A). Methods: A Peg-Board Phantom was used in our study. The phantom consisted of 32 rods which were used for target localization; the height and the location of the rods were in normal distribution. For 3D DSA (Infinix NS/VC, Toshiba), the raw data was reconstructed to 3D images on the DSA workstation, and transferred to a online PC workstation where it was converted to standard 2D DICOM image data using WFU DICOM T oolkit software. For MRI (A), the phantom was scanned with FSPGR sequence on the MRI scanner (GE Signa VH/i 3.0 T), and the DICOM images were also transferred to the online PC workstation. Using the software 3D Slicer registration was performed on the PC workstation by using the location and shape of the rods in the phantom. The localization error of the rods was measured in image space as the Euclidean distance between targets defined in image space and those detected in the physical space. Paired t test was used to evaluate the difference between the accuracy of neuronaviagtion of 3D DSA and that of MRI(A). Results: Through the coregistration of the rods in the phantom from different modality, all the images were better coregistrated. The mean localization error was (0.38 ± 0.24)mm (3D DSA) and (0.31 ± 0.12)mm[MRI(A)]. There was no significant statistical difference between the accuracy of neuronavigation of 3D DSA and MRI(A) (t=-0.601, P=0.55). Conclusion: 3D DSA images can be used in the neuronavigation system through the coregistration of 3D DSA and MRI(A). (authors)

Chronic thromboembolic pulmonary hypertension: diagnostic impact of multislice-CT and selective pulmonary-DSA

International Nuclear Information System (INIS)

Pitton, M.B.; Kemmerich, G.; Herber, S.; Schweden, F.; Thelen, M.; Mayer, E.

2002-01-01

Purpose: To evaluate the diagnostic impact of multislice-CT and selective pulmonary DSA in chronic thromboembolic pulmonary hypertension (CTEPH). Methods: 994 vessel segments of 14 consecutive patients with CTEPH were investigated with multislice-CT (slice thickness 3 mm, collimation 2.5 mm, reconstruction intervall 2 mm) and selective pulmonary DSA posterior-anterior, 45 oblique, and lateral projection. Analysis was performed by 2 investigators independently for CT and DSA. Diagnostic criteria were occlusions and non-occlusive changes like webs and bands, irregularities of the vessel wall, diameter reduction and thromboembolic depositions at different levels from central pulmonary arteries to subsegmental arteries. Reference diagnosis was made by synopsis of CT and DSA by consensus. Results: Concerning patency CT and DSA showed concordant findings overall in 88.9%, 92.9% for segmental arteries and 85.4% for subsegmental arteries. Concerning any thromboembolic changes, multislice-CT was significantly inferior to selective DSA (concordance 67.0% overall, 70.4% for segments and 63.6% for subsegments). Non-occlusive changes of the vessels were significantly underdiagnosed by CT (concordance of CT versus DSA: 23.1%). Conclusion: Multislice-CT and selective pulmonary DSA are equivalent for diagnosis of vessel occlusions at the level of segmental and subsegmental arteries. However, for visualisation of the non-occlusive thromboembolic changes of the vessel wall selective pulmonary DSA is still superior compared to multislice-CT. Multislice-CT and selective pulmonary DSA are complementary tools for diagnosis and treatment planning of chronic thromboembolic pulmonary hypertension (CTEPH). (orig.) [de

DSA diagnosis and interventional management of postoperative bleeding

International Nuclear Information System (INIS)

Li Yuwei; Zhang Fuqiang; Li Yunhui; Yuan Liang; Si Guangyan; Liu Lili

2009-01-01

Objective: To discuss the clinical application of DSA and interventional management in diagnosing and treating the bleeding after surgery. Methods: The clinical data and the interventional management of 14 patients with DSA-proved postoperative bleeding, encountered during the period of Aug. 2005-Jan. 2008, were retrospectively analyzed. The surgeries included subtotal gastrectomy (n=4), pancreatoduodenectomy (n=3), cesarean section (n=2), nephrolithotomy (n=3), heminephrectomy (n=1), internal hemorrhoidectomy (n=1). Results: Seventeen arterial bleeding sites were demonstrated, including gastroduodenal (n=2), left gastric (n=4), phrenic (n=1), short gastric (n=1), superior mesenteric (n=2), renal (n=4), uterine (n=2) and internal pudendal (n=1) artery. The diagnosis was confirmed with DSA in all 14 patients, of which embolization was successfully carried out in 13 in one session (92.8%). The remaining one case had to be operated again to stop the bleeding because of the failure of the superselective catheterization. No serious complications, such as organ necrosis or visceral dysfunction, occurred. Conclusion: As a safe, minimally-invasive and effective technique, DSA and interventional management are very helpful in diagnosing and treating the bleeding after surgery. (authors)

Value of infusion-DSA (Digital Subtraction Angiography) in diagnosis of primary hepatocellular carcinoma

International Nuclear Information System (INIS)

Kwon, Jeong Mi; Kim, So Sun; Huh, Jin Do; Kim, Ho Joon; Chun, Byung Hee; Joh, Young Duk

1991-01-01

In order to evaluate diagnostic effectiveness of the infusion-study, the authors prospectively evaluated hepatic digital subtraction angiography of bolus and infusion studies in 71 patients with hepatocellular carcinoma. In contrast to Bolus-DSA, which involves a 2 second injection of 10cc of contrast medium, the Infusion-DSA uses a protracted (10sec) injection, a lower injection rate, and larger total dose of contrast medium (20cc). The information yield of arterial and capillary phases of Infusion-DSA was compared with that of Bolus-DSA and graded as 'improved(+)', 'equivalent( ± )', or 'poor(-)'. Also, the contribution of Infusion-DSA to the diagnosis was classified into one of five in a graded system. In 29 hepatocellular patients, the Infusion-DSA was helpful in detecting daughter nodules, fibrous capsule and arteriovenous shunt. Infusion-DSA is a useful complementary technique in the diagnosis of hepatocellular carcinoma and was also helpful in determining the selection of the therapeutic modality of hepatocellular carcinoma

The analysis of cerebro-vascular circulation time using digital subtraction angiography (DSA)

International Nuclear Information System (INIS)

Han, D. G.; Kim, D. H.; Lee, H. K.; Kwon, K. H.; Kim, K. J.

1986-01-01

We analyzed the cerebral arterio-venous circulation time of 141 cases of cranial DSA in 136 patients, for the assessment of cerebral circulatory dynamics. IV-DSA was 111 cases, IA-DSA 30 cases. The results were as follows: 1. There was no significant difference in arterio-venous circulation time between IA-DSA and IV-DSA, if the disease pattern was not considered (P > 0.1). 2. Prolongation of arterio-venous circulation time was noted in the cases of cerebral (cerebellar) hemorrhage, subarachnoid hemorrhage, intracranial hematoma, brain abscess, acute stage of cerebra-vascular occlusive disease, acute stage of postoperative follow up, and acute stage of cerebral contusion (p > 0.05). 3. Compared the chronic stage of cerebra-vascular occlusive disease, postoperative follow up, and cerebral contusion with acute stage, significant decrement of arterio-venous circulation time was resulted (p > 0.05). 4. DSA was a useful modality for the assessment of circulatory dynamics, including measurement of arterio-venous circulation time.

Evaluation of the cerebral vasculature by intrarterial DSA - with emphasis on in vivo resolution

International Nuclear Information System (INIS)

Takahashi, M.; Bussaka, H.; Nakagawa, N.

1984-01-01

Comparative study was performed between IA DSA and stereoscopic magnification angiography in relation to small vessel resolution, image quality of the vessels and image quality of various pathologic lesions. The vessels of various diameters accurately measured by stereoscopic magnification angiography, were localized on IA DSA and their resolution was carefully assessed. The vessels more than 1 mm in diameter were equally visualized on IA DSA and conventional angiography. The vessels between 1 mm and 0.5 mm showed fair resolution on IA DSA, whereas IA DSA did not resolve the vessels smaller than 0.5 mm in diameter to good advantage. In addition, image quality of the vessels on IA DSA was compared with the conventional methods. Cerebral gyrus, venous sinuses, and intracerebral veins are often shown better on DSA. The small vessels such as lenticulostriate, small cortical, thalamoperforate and meningohypophyseal arteries were not defined on DSA. Equal or better image quality was obtained in more than 85% of cases with pathologic lesions. Examinations were performed faster with lower cost and lower complication rate. Information provided by DSA was often sufficient for managements of patients. Combined use of DSA and conventional angiography will improve diagnostic accuracy and decrease the complication rate. (orig.)

The possible critical role of T-cell help in DSA-mediated graft loss.

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Süsal, Caner; Slavcev, Antonij; Pham, Lien; Zeier, Martin; Morath, Christian

2018-06-01

In this review, we discuss a possible central role of T-cell help in severe forms of graft damage mediated by donor-specific HLA antibodies (DSA). Some kidney transplant recipients with pretransplant DSA show a high graft failure rate, whereas in other patients DSA do not harm the transplanted kidney and in most cases, disappear shortly after transplantation. Analyzing 80 desensitized highly immunized kidney transplant recipients and another multicenter cohort of 385 patients with pretransplant HLA antibodies, we reported recently that an ongoing T-cell help from an activated immune system, as measured by an increased level of soluble CD30 in serum, might be necessary for the DSA to exert a deleterious effect. Patients positive for both pretransplant DSA and sCD30 appear to require special measures, such as the elimination of DSA from the circulation, potent immunosuppression, good HLA-matching, and intense post-transplant monitoring, whereas exclusion of DSA-positive patients from transplantation in the absence of high sCD30 may not be justified in all cases, even if the pretransplant DSA are strong and complement-activating. © 2018 Steunstichting ESOT.

The DSA appearance and its clinical significance in renovascular hypertension

International Nuclear Information System (INIS)

Su Guoqiang; Zhu Yaoqing; Gao Chongjing

2000-01-01

Objective: To discuss the DSA appearance of renovascular hypertension and the feasible necessity of dilatation of stenotic renal artery. Methods: DSA data of bilateral renal arteries of 21 patients, with suspected renovascular hypertension were analyzed. Results: Among those 21 patients, 11 did have stenoses in renal artery or its branches. Balloon dilatation were performed successfully in 6 patients. The successful rate was 54.55%. Conclusions: DSA is the preferable method for the diagnosis of renovascular hypertension, and offers reliable clinical data for interventional therapy

Incidence and Factors Associated with De Novo DSA After BK Viremia in Renal Transplant Recipients.

Science.gov (United States)

Patel, Samir J; Kuten, Samantha A; Knight, Richard J; Graviss, Edward A; Nguyen, Duc; Gaber, A Osama

2016-01-01

BK polyomavirus infection and de novo donor-human leukocyte antigen (HLA) specific antibodies (dnDSA) are two well-known and distinct complications occurring after kidney transplantation. Recent literature suggests an association between the two events. This study aims to examine the relationship between BK viremia (BKV) and dnDSA and to identify potential risk factors for dnDSA following BKV in kidney transplant recipients. A retrospective review of 1019 recipients from Houston Methodist Hospital was conducted. All patients underwent routine screening for BKV and dnDSA. Median follow-up was 44 months. BKV was detected in 186 (18%) patients at a median of 107 (82-205) days post-transplant. dnDSA occurred in 283 (28%) patients at a median of 272 (62-575) days post-transplant. Of the 69 dnDSA-positive/BKV-positive patients, dnDSA detection occurred after BKV onset in 46 patients. Thus, 46 (28%) previously DSA-negative patients later became dnDSA-positive following BKV, not significantly different from the rate seen in BKV-negative patients (26%; p=0.5). Median time to DSA detection following BKV onset was 232 days (interquartile range, 119-460) post-BKV detection. Multivariate analysis revealed a greater number of HLA mismatches and viral clearance as risk factors for development of dnDSA following BKV, whereas delayed graft function was associated with a lower risk of dnDSA. In conclusion, despite being considered a result of over-immunosuppression, BKV can still be followed by dnDSA in a substantial proportion of patients. Monitoring for dnDSA in patients being managed for BKV may be warranted. Copyright© 2017 by the Terasaki Research Institute.

Carbon dioxide hepatic arterial DSA and CT angiography in swine model

International Nuclear Information System (INIS)

Tan Huaqiao; Hu Hongjie; Huang Wenxin; Zhang Shizheng; Dong Yonghua; Zhou Dachun

2005-01-01

Objective: To evaluate the imaging findings of carbon dioxide hepatic arterial DSA and CT angiography in normal swine. Methods: In general anaesthesia, hepatic arterial DSA was performed with 10 ml iodinated contrast medium (5 ml/s, 10 ml) in 5 normal swine, and then repeated hepatic arterial CO 2 -DSA was performed with a total of 30-50 ml CO 2 injected by manually operated syringe at the velocity of 5-8 ml/s, followed by CO 2 -CT angiography. All the swine were sacrificed after the procedure, the selective hepatic segments were removed, and pathological examination was carried out. The radiological features of hepatic arterial DSA with iodinated contrast medium and CO 2 and CT angiography with CO 2 were analyzed. The ability of showing the arterio-venous shunt was compared. Results: Hepatic arterio-portal shunt was found in the advanced arterial phase of CO 2 -DSA in three of five swine, which was furthermore demonstrated by CO 2 -CT angiography, but iodinated contrast medium DSA showed no arterio-portal shunt in all swine. The gaseous CO 2 in portal vein was absorbed within 1-3 minutes. No CO 2 shunted into the hepatic vein during CO 2 -DSA and CO 2 -CTA. Histology didn't reveal any abnormal changes caused by CO 2 shunt in the swine liver. Conclusion: (1) Hepatic arterial CO 2 -DSA and CO 2 -CTA can reveal arterio-portal shunt that isn't seen with iodinated contrast medium, the gaseous CO 2 in portal vein was absorbed within 1-3 minutes. (2) The gaseous CO 2 can't shunt into hepatic vein when the hepatic artery is perfused with CO 2 in normal swine. (authors)

The protection of radioactive nuclide and nursing management in DSA room

International Nuclear Information System (INIS)

Zhang Guimin

2009-01-01

Objective: To discuss the protection of radioactive nuclide and nursing management in DSA room. Methods: The clinical state of the protection of radioactive 131 I nuclide and nursing management in DSA room was retrospectively summarized. Results: The standard management for the protection of radioactive nuclide in DSA room was established. The main management schemas included the management of personnel, the management of professional skills and, specialty, the management of radioactive drugs and abandoned odds and ends, preoperative health education, etc. Conclusion: The standard management can ensure that the patients get a good radionuclide therapy in DSA room, and, at the same time, the working environment can be effectively protected and the professional nursing staff can be well trained. (authors)

Clinical application of digital subtraction angiography (DSA)

International Nuclear Information System (INIS)

Morimoto, Tadashi; Kaku, Suiei; Morikawa, Eiji

1984-01-01

Intra-arterial digital subtraction angiography (IA-DSA) by the direct puncture of the carotid artery was described with special reference to its techniques, and cases were presented. This method was safe and painless and could be performed repeatedly. Cerebral angiographic images obtained by this method were either superior or fully compatible to the conventional cerebral angiography. It is therefore of great diagnostic value and can replace the conventional method. Furthermore, since the pretreatment is unnecessary and the time required is short, IA-DSA can be used as an adjuvant method for emergency diagnosis. (Namekawa, K)

Indications for intravenous and intraarterial digital subtraction angiography (DSA) in the diagnosis of cerebrovascular insufficiency

International Nuclear Information System (INIS)

Neufang, K.F.R.; Friedmann, G.

1985-01-01

For screening of arteriosclerotic lesions of the carotid bifurcation duplex scanning (B-mode imaging plus doppler flow analysis) is the method of first choice, because it is really noninvasive and offers the same results as intravenous DSA (IV DSA). IV DSA should not be performed as a screening procedure unless ultrasound examinations are not available or are inadequate. Except for patients with isolated unilateral stenosis of the internal carotid artery near the bifurcation confirmed with both duplex scanning and IV DSA, arteriography is required for therapy planning. Aortic arch angiogram, selective extra- and intracranial carotid arteriography and - if necessary - vertebral and subclavian arteriography can be performed with intraarterial DSA (IA DSA). The application of DSA to catheter arteriography will help to reduce further the potential risk of adverse reactions related to high intravasal contrast does specially in the cerebral circulation, but will not turn arteriography into a risk-free procedure. Postoperative examinations of the carotid bifurcation can be performed with ultrasound as well as with IV DSA. Extracranial bypasses are best demonstrated with IV DSA. Extraintracranial bypasses can be demonstrated only with IA DSA. (orig.)

Preoperative imaging in 78 living kidney donors using CE-MRA and DSA

International Nuclear Information System (INIS)

Lemke, U.; Taupitz, M.; Hamm, B.; Kroencke, T.J.; Kluener, C.; Giessing, M.; Schoenberger, B.

2008-01-01

Purpose: to evaluate contrast-enhanced 3D magnetic resonance angiography (CE-MRA) and digital subtraction angiography (DSA) in comparison with the intraoperative findings in living kidney donors. Materials and methods: a total of 156 kidneys in 78 potential kidney donors were prospectively examined using CE-MRA (0.2 mmol Gd/kg, voxel size 1.3 x 0.8 x 2.0) and DSA. Two experienced radiologists assessed the images in consensus regarding the renal vascular anatomy and variants. The results for the 67 candidates accepted for donation were compared to the intraoperative findings. In the other kidneys not accepted for donor nephrectomy, MRA and DSA were compared with each other. Results: nineteen arterial variants were identified intraoperatively, of which 11 (58%) were also detected by preoperative CE-MRA and 10 (53%) by preoperative DSA. Of the 10 venous variants found intraoperatively, CE-MRA detected 8 (80%) and DSA 3 (30%). The agreement (kappa test) between MRI and DSA for all 156 evaluated kidneys was 0.7 for arterial variants (McNemar p = 0.12) and 0.3 for venous variants (McNemar p = 0.01). The preoperative choice of kidney (right or left) made on the basis of the renal vascular anatomy seen on CE-MRA and DSA differed in 22% of the 78 potential donors (McNemar P = 0.3). (orig.)

The availability of DSA used continuous intraarterial infusion tubes founded various malignancy

International Nuclear Information System (INIS)

Minakuchi, Kazuo; Kobayashi, Nobuyuki; Yamada, Tetsuya

1987-01-01

DSA was employed using continuous intraarterial infusion tubes for various malignancies (73 cases) which were examined a total of 135 times. In head and neck malignancy (50 cases), the general position of the infusion tube had been determined beforehand by dye infusion, but DSA from the tube showed that the tubes in 24 cases (48 %) were located in the wrong position, especially in tongue cancer (21 cases) where many tubes were discovered to be in an erroreous position (71 %) such as the common carotid artery. We were unable to determine the effect of chemotherapy and radiation using DSA only. In 9 cases of breast cancer for which fixation of the tube was not attempted under X-ray fluoroscopy, 7 (78 %) showed an unusual tube position such as the intraaortic arch. In 5 cases of abdominal malignancy, only the tube position for sigmoid colon cancer was unusual. We were able to observe the effect of chemotherapy by DSA in 2 cases. For DSA in one out of 3 hepatomas using a Port-A-Cath, we observed that infusion of anticancer drug with degradable starch microspheres caused a reduction in tumor size. However, in the two remaining cases, we were unable to observe any effect of infusion of these drugs by DSA for various mechanical reasons. DSA from an infusion tube revealed not only the location of the tube accurately and promptly, but also the effect of chemotherapy. (author)

The clinical application of inferior vena caval CO2-DSA

International Nuclear Information System (INIS)

Guo Jinhe; Teng Gaojun; Zhu Guangyu; Li Guozhao; Fang Wen; He Shicheng; Deng Tang

2007-01-01

Objective: To explore the feasibility and safety of inferior vena caval CO 2 -DSA and evaluate the results of inferior vena cavography using CO 2 -DSA or iodinated contrast media. Methods: 25 patients diagnosed as deep venous thrombosis of lower limb were prepared to conceive the implantation of inferior vena caval filter. The inferior vena cava and right renal vein CO 2 -DSA and iodinated contrast media DSA were carried out through jugular or femoral vein approach in all patients. Results: The inferior vena caval angiography with CO 2 -DSA or iodinated contrast media were carried out successfully in all patients. The quality of the inferior vena caval angiogram showed: with CO 2 as contrast media, 14 cases obtained excellent images and 11 cases had good images; with iodinated contrast media the images of 18 cases were excellent and 7 cases were good. No thrombus and variation of inferior vena cava were found by the two kinds of angiography. The diameter of inferior vena cava showed: (20.01 ± 0.83) mm with CO 2 contrast media and (20.15 ± 0.92) mm with iodinated contrast media, (P=0.006); having statistical significance between them. The safety of angiography with CO 2 presented only 1 case with transient slight decrease of O 2 saturation. No abnormal changes were found in blood pressure, heart rate and so on. Conclusions: Inferior vena caval CO 2 -DSA is feasible and safe, with statistical significance in the measurement of inferior vena caval diameter comparing with iodinated contrast material but with no influence on the implantation of filter. (authors)

Correlation between the clinical presentation and DSA of intracranial aneurysms

International Nuclear Information System (INIS)

Fang Chun; Hua Jia; Chen Kemin; Yin Yan; Ge Xin; Ying Yiping

2001-01-01

Objective: To evaluate the correlation between the clinical presentation and cerebral angiographic features of intracranial aneurysms. Methods: The authors retrospectively analyzed the relationship between the size, location and shape of 48 patient's cerebral aneurysms and their clinical presentations. Results: Clinical symptoms of cerebral aneurysms were related with their size, location and shape. Aneurysms in different location or at same location may cause similar symptoms or different symptoms. Rotation DSA is a useful examination supplemented to conventional DSA. Conclusions: The relationship between the location and the presentation of intracranial aneurysms is not specific. Rotation DSA plays important role in showing the characteristics of the cerebral aneurysms

Dsa examination and diagnosis of arteriovenous shunts in hepatic cavernous hemangiomas of adults

International Nuclear Information System (INIS)

Ouyang Yong; Ouyang Xuehui; Gu Subin; Zhou Qunhui

2000-01-01

Objective: To correct the misunderstanding that arteriovenous shunts (AVS) are rarely found in adult cavernous hemangiomas of the liver (CHL) and to increase its diagnosis rate by DSA. Methods: DSA examination and DSA images of thirty adults with definitely diagnostic CHL and without evidence of other hepatic diseases and hepatic injury were analyzed retrospectively. X-ray films of 21 cases with AVS taken immediately after transcatheter arterial embolization using lipiodol (L-TAE) were compared with the corresponding DSA images to check up those AVS opacified in DSA by observing sediment and distribution of iodized oil injected. Results: Definite diagnosis of AVS by DSA were obtained in 22 cases of this series (73%). All the AVS were located in the peritumoral parenchyma and appeared as parallel track sign, and early opacification of small draining veins, etc. during arterial phase of DSA. X-ray films taken immediately after L-TAE in 21 of 22 cases with AVS showed that few portal radicles or draining veins were refilled by iodized oil through incompletely occluded shunts in 11 cases, and no any vein was refilled by iodized oil resulted from complete occlusion of the present AVS in 10. No definite AVS was found in the other 8 cases of this series, and in 6 of them improper imaging factors of DSA were used. Conclusion: This study serves to emphasize that AVS is not a diagnosis of hepatic malignancy, but is frequently seen in the commonly benign CHL of adults. Proper imaging factors of DSA and superior images can be helpful to opacify small AVS of CHL. The formation of AVS in CHL may be closely related to the pathological changes of peritumoral parenchyma, however, its mechanism must be further studied

Complications of intravenous DSA: Results in 500 patients

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Gross-Fengels, W.; Neufang, K.F.R.; Beyer, D.; Steinbrich, W.

1987-01-01

500 patients were studied respectively for complications of intravenous digital subtraction angiography (IV-DSA) performed with non-ionic contrast media, using a central venous injection technique. In 21 patients (4,2%) during or shortly after the procedure 23 systemic, 1 neurologic, and 7 local complications occurred. In addition, 1 patient developed acute renal failure 26 hours after the IV-DSA, whereas 4 patients later showed on thromboses of the catheterised vein. No permanent neurologic or systemic complications and severe allergic reactions were seen. (orig.) [de

Measurements of image characteristics of DSA installations

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Busch, H.P.; Strauss, L.G.; Freimarck, R.D.

1984-01-01

Measurements for quantifying the image characteristics were carried out on three DSA installations (DVI 1 - Philips, Angiotron - Siemens and DF 3000 - General Eletric). Contrast resolution was measured with a vessel phantom (General Electric) and spatial resolution with a lead grid. A further parameter was the dose entering the image intensifier. The Angiotron was used with an intensifier with 53 cm. diameter and the DF 3000 with temporal subtraction of the video images and the subtraction of dual energy images (hybrid technique). These measurements can be carried out quickly and easily and are a step towards standardisation of measurements of image characteristics of DSA installations. (orig.) [de

Visceral angiography with intra-arterial DSA and a programmed 100 mm technique

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Triller, J.; Ackermann, B.; Jung, H.

1988-01-01

One hundred and seventy specially selected visceral angiograms were carried out of 96 patients using I-A DSA and 100 mm technique. 85.2% of the I-A DSA and 91.7% of the 100 mm images were of good quality. I-A DSA produced comparable or better quality than the 100 mm technique in 66% during the arterial phase, in 79% during the paranchymatous phase and in 70% during the venous phase. The 100 mm technique produced better quality in a third of the cases during the arterial phase and in a quarter of the cases during the parenchymal and venous phases. The indications for the 100 mm technique are failure of I-A DSA or the need for high spatial resolution. (orig.) [de

Prediction of tumor-brain adhesion in intracranial meningiomas by MR imaging and DSA

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Takeguchi, Takashi; Miki, Hitoshi; Shimizu, Teruhiko; Kikuchi, Keiichi; Mochizuki, Teruhito; Ohue, Shiro; Ohnishi, Takanori

2003-01-01

The purpose of this study was to evaluate the usefulness of MRI (magnetic resonance imaging) and DSA (digital subtraction angiography) by using preoperative MRI and DSA findings in the examination of meningiomas before excision. In particular, we focused on their usefulness in predicting tumor-brain adhesion during surgery. The subjects were 36 patients with intracranial meningioma who underwent tumor excision at which time neurosurgeons examined the tumor-brain adhesion. Two neurosurgeons evaluated the degree of tumor-brain adhesion from operation records and videotapes recorded during surgery. Two neuroradiologists retrospectively evaluated the preoperative MRI findings including tumor diameter, signal intensity of the tumor parenchyma obtained with T 2 -weighted imaging (T 2 WI), characteristics of the tumor-brain interface, and degree of peritumoral brain edema. The vascular supply was also evaluated from the preoperative DSA findings. The relationship between these MRI and DSA findings and the degree of tumor-brain adhesion during surgery as classified by the neurosurgeons was statistically analyzed. The degree of peritumoral brain edema and the shapes and characteristics of the tumor-brain interface, including the findings of FLAIR (fluid-attenuated inversion recovery) imaging and vascular supply observed by DSA, were significantly correlated with tumor-brain adhesion. In particular, the shapes and characteristics of the tumor-brain interface as observed by T 1 -weighted imaging (T 1 WI), T2WI, and FLAIR, respectively, as well as the vascular supply observed by DSA, were closely correlated with the degree of tumor-brain adhesion encountered during surgery. According to these results, we developed a method of predicting tumor-brain adhesion that considers the shape of the tumor-brain interface revealed by MRI and the vascular supply revealed by DSA. We retrospectively examined the findings of MRI and DSA performed before excision of meningioma and clarified

Adjusting the displaced tip of peripherally inserted central catheter under DSA guidance

International Nuclear Information System (INIS)

Mao Yanjun; Dong Huijuan; Zhang Lingjuan; Li Hongmei; Xu Lianqin

2009-01-01

Objective: To explore a new method to adjust the displaced tip of peripherally inserted central catheter (PICC) under DSA guidance. Methods: Under DSA guidance, the displaced tip of PICC was repositioned to the ideal junction area of superior vena cava with right atrium with proper manipulation. Results: Under DSA guidance, the displaced tip of PICC was successfully corrected in 13 cases. The mean operative time was 15.53 minutes, which was markedly shorter than that needed by blind adjusting beside the bed. Conclusion: The displacement of PICC tip is a common occurrence, which is hard to be avoided. Under DSA guidance, the adjusting manipulation of the displaced PICC tip is safe and time-saving with high successful rate. It is worth popularizing this technique in clinical practice. (authors)

Internal carotid artery stenosis or occlusion: study of collateral circulation pathways on DSA and MRA

International Nuclear Information System (INIS)

Zhao Yunhui; Ma Zhubin; Xu Yikai

2004-01-01

Objectives: To evaluate the collateral pathways of internal carotid artery (ICA) stenosis or occlusion on digital subtraction angiography (DSA) and magnetic resonance angiography (MRA), and to compare these two methods in the study for collateral pathways. Methods: Seventy-four patients with ICA stenosis or occlusion were included as the study group. Sixty persons with normal findings on DSA or MRA each served as the control group. DSA, MRA, MRI, CT findings, and clinicall materials were analyzed in the two groups. Results: Stenosis or occlusion over ICA bifurcation was showed clearly in all patients on DSA or MRA. On DSA, the presence rate of ipsilateral posterior communicating artery (PCoA) in the study group (82.5%) was lower significantly than that of the control group (94.2%) (P=0.025). On MRA (3D-TOF), the rate in the study group (59.3%) was higher significantly than that of the controls (30.0%) (P=0.000). On DSA and MRA, the diameter of ipsilateral PCoA in the study group was larger than that of the control group (P=0.000). On DSA, the presence rate of OPhA in the study group was significantly different from that of the control group, and its diameter was larger than that of the control group (P=0.003). On MRA, its presence rate was lower than that of the control group. The presence rate of anterior communicating artery (ACoA) in the study group showed no statistical difference between DSA and MRA. In the study group, the presence rate of PCoA on DSA was significantly higher than that on MRA (P 0.05). The diameters of the three arteries showed no significant differences between DSA and MRA (P>0.05). Conclusion: DSA is highly valuable for the evaluation of collateral pathways of ICA stenosis or occlusion, and it is necessary for preoperative examination. MRA is a non-invasive angiographic method and can evaluate collateral circulation in both morphology and function, and can be the preferred method for the disease. (authors)

Intra-arterial digital subtraction angiography (IA-DSA) with carbon dioxide

International Nuclear Information System (INIS)

Takeda, Toshiaki; Ido, Kunio; Yuasa, Yuji

1988-01-01

Intra-Arterial Digital Subtraction Angiography (IA-DSA) with Carbon Dioxide (CO 2 ) was performed on 41 patients mainly with liver or renal diseases, and its angiographic manifestation was compared with that of conventional angiography. Although the image quality of the arterial or capillary phase was inferior to that of conventional angiography with iodinated contrast media, the detectablity of arterio-venous shunting was excellent. In fact, DSA with CO 2 revealed the presence of A-V (A-P) shunt in 26 patients (26/41:63.4 % HCC, 13/15:86.7% metastatic liver tumor, 2/3:66.7 % RCC, 1/5:20 %). On the other hand, conventional angiography was able to show in only 5 cases. DSA with CO 2 will become an effective method for detecting minute arterio-venous shunting which can not be demonstrated with conventional angiography. (author)

Evaluation of DSA test phantoms commercially available in the UK

International Nuclear Information System (INIS)

Cowen, A.R.; Coleman, N.J.; HArtley, P.J.

1985-01-01

Several digital subtraction angiography systems have been installed in the United Kingdom. Many others will no doubt be installed over the next few years. Given the high cost and technical complexity of DSA systems it is natural that the purchasers of such equipment should be concerned that their machine has been adjusted correctly prior to clinical acceptance and continues to operate satisfactorily thereafter. In response to these concerns several companies in the U.K. are now selling DSA test phantoms. All DSA phantoms which are currently commercially available are manufactured in the U.S.A. Im order to assess the effectiveness of these phantoms the DHSS has initiated the assessment project described here. The findings are tabulated . Performance is indicated by a star rating system, based on the opinions of two X-ray engineers and one medical physicist. (author)

IV-DSA of vertigo patients

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Watanabe, Hiromi; Ito, Masatoshi; Takita, Kimio; Matsuzawa, Taiju.

1988-01-01

With IV-DSA(Intra-Venous Digital Subtraction Angiography), we examined the relations between vertigo or dizziness and asymmetries of cervical vertebral arteries. In this time, as the asymmetries we chose next three; hemi-stenosis, hemi-occulusion and hemi-strong tortuosity. In the appearance of the asymmetries, there was no differance between those who complain vertigo or dizziness and others. (author)

DSA volumetric 3D reconstructions of intracranial aneurysms: A pictorial essay

Science.gov (United States)

Cieściński, Jakub; Serafin, Zbigniew; Strześniewski, Piotr; Lasek, Władysław; Beuth, Wojciech

2012-01-01

Summary A gold standard of cerebral vessel imaging remains the digital subtraction angiography (DSA) performed in three projections. However, in specific clinical cases, many additional projections are required, or a complete visualization of a lesion may even be impossible with 2D angiography. Three-dimensional (3D) reconstructions of rotational angiography were reported to improve the performance of DSA significantly. In this pictorial essay, specific applications of this technique are presented in the management of intracranial aneurysms, including: preoperative aneurysm evaluation, intraoperative imaging, and follow-up. Volumetric reconstructions of 3D DSA are a valuable tool for cerebral vessels imaging. They play a vital role in the assessment of intracranial aneurysms, especially in evaluation of the aneurysm neck and the aneurysm recanalization. PMID:22844309

IV DSA in the diagnosis and follow-up of dissection of the thoracic aorta

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Hendrickx, P.; Luska, G.; Laas, J.; Haverich, A.

1986-05-01

Intravenous DSA was performed in 53 patients with suspected dissection of the thoracic aorta and in 13 patients following surgery for aortic dissection. In 36 patients, the suspected diagnosis could be excluded definitely and, in 14 cases out of 17, a dissection was correctly diagnosed. All 11 type B dissections were correctly diagnosed. Of six type A dissections, only three were adequately demonstrated by IV DSA. In type B dissections, IV DSA is reliable, but in type A dissection with massive aortic insufficiency or pericardial tamponade the findings are not reliable. In all 13 patients who had surgery for dissection, IV DSA proved suitable for showing the anastomosis and progress of the disease.

Study of DSA-guided percutaneous puncture location of foramen oval

International Nuclear Information System (INIS)

Zhao Xiaojun; He Jiawei; Bai Guanghui; Shi Jianjing; Xu Chongyong; Zhan Gonghao

2008-01-01

Objective: To study the technique of digital substraction angiography (DSA)-guided percutaneous puncture location of foramen oval. Methods: 39 cases of trigeminal neuralgia were included in the study from Feb. 2004 to Oct. 2006. The patients were punctured by the amending anterior position. The f0ramen oval was displayed by moving the tube tilted 20-28 degree to the caudal and 16-23 degree to the healthy side. The direction and depth of the needles was determined on the lateral view. Then, radio-frequency thermocoagulation therapy was performed. Results: The needles were located in oval foramen in all the patients. Pain disappeared in 36 cases, alleviated in other cases, and no serious complication occurred during therapy. Conclusions: Oval foramen locations by DSA can improve the successful rate of operation. The foramen oval can be clearly displayed by DSA-guided in amending position, with comfortable position for patients. (authors)

Advantages and limitation of intra-arterial digital subtraction angiography (i.a. DSA)

International Nuclear Information System (INIS)

Beduhn, D.

1986-01-01

Among 3000 digital subtraction angiographies which have been performed in our institute, 850 patients have been examined intraarterially. The advantage of i.a. DSA is due to the excellent demonstration of vessels in survey angiograms by small amounts of contrast medium (10-20 ml in the aorta), without risk of selective catheterisation into the neck vessels, the saving of expensive film series, the short duration of vessel examinations and the small complication rate. i.a. DSA can be carried out on outpatients also, using the 4/5 F-catheter, which saves hospital charges. Impressive examples show the advantages of i.a. DSA. (orig.) [de

The study of the value of applying the special functions of DSA during uterine artery embolization

International Nuclear Information System (INIS)

Wang Ting; Zhao Zhenhua; Lv Weigong

2007-01-01

Objective: To study the value of applying the special functions of DSA during uterine artery embolization. Methods: 122 cases were performed uterine artery embolization, including 67 cases with traditional operation and 55 cases with applying the special functions of DSA: rotary DSA angiography, the best work position and road map technology. We recorded the correlative operative indices to compare and analyse the mean exposure time, the mean operative time, the mean dosage of contrast medium, the probability of vasospasm and injury of blood vessel during operation. Results: The mean exposure time, mean operative time and the mean dosage of contrast medium were reduced with the special functions of DSA during uterine artery embolization. There is significant difference between traditional operation and the operation applying the special functions of DSA (P<0.01). Conclusion: Applying the special functions of DSA during uterine artery embolization can reduce the operative time, operative risk and economic burden. (authors)

Diagnostic value of digital subtraction angiography (DSA) using TOSHIBA DIGIFORMER X in the cerebrospinal vascular diseases

International Nuclear Information System (INIS)

Ishikawa, Tatsuya; Nakagawa, Yoku; Sawamura, Yutaka; Kobayashi, Nobuaki; Nagashima, Masafumi; Kitaoka, Ken-ichi; Kitagawa, Michio; Itoh, Terufumi; Ohsato, Takao.

1987-01-01

Using TOSHIBA Digiformer X, digital subtraction angiography (DSA) was performed in 286 patients, in whom 229 patients of cerebro-spinal vascular disease was included. The authors emphasize the usefulness of DSA in cerebro-spinal vascular disease in relation to conventional angiography. DSA taken by single small dose injection of contrast medium into the ascending aorta clearly demonstrates not only aortic arch and thoracic major vessels, but also cervical vessels and all intracranial vessels. Therefore, we could rapidly understand gross dynamics of the circulation and obtain useful informations prior to catheterization to the selective artery. This advantage of DSA was particularly useful for occlusive vascular diseases. Gradual injection of small dose of contrast medium obviously reduced recoiling of the catheter tip, which enabled the selective angiography with setting of the tip of the catheter at the entrance of cervical major vessels without its sufficient inserion into the selective vessels. This advantage is particularly beneficial for the patients with severe arteriosclerosis who was found to be difficult for selective catheterization. In our experience, demonstration of a presence of aneurysm by DSA was possible in almost all cases of subarachnoid hemorrhage, although spatial resolution of DSA is said to be inferior to the conventional angiography. Real time display of DSA decreased the time required for examination and enabled repeated angiography. This advantage of DSA is especially useful for the patients with spinal arterio-venous malformation and thoracic outlet syndrome. (author)

The clinical value of the special functions of DSA in interventional embolization for uterine fibroids

International Nuclear Information System (INIS)

He Yushen; Lu Dong; Lv Weifu; Zhang Jingsong

2009-01-01

Objective: To evaluate the special functions of DSA in interventional embolization therapy for uterine fibroids. Methods: The special functions of DSA, including 3D-DSA, the optimal working position and road-mapping technique, were utilized in performing interventional embolization therapy for uterine fibroids in twenty-six cases (experimental group). Routine DSA angiography was employed in twenty cases(control group). The volume of contrast media used, the time of completing the interventional procedure and the total fluoroscopic time in two groups were compared and the results were analyzed. Results: The difference in the volume of contrast agent used and in the total fluoroscopic time between two groups was statistically significant (P 0.05). Conclusion: In treating uterine fibroids with interventional embolization, the use of the special functions of DSA can reduce the manipulation time and lower the operation risk. Moreover, the technique of visible 3D reconstruction image is of great significance in guiding the procedure. (authors)

Clinical application of DSA and evaluation of its methods

International Nuclear Information System (INIS)

Ouyang, Yong; Ma, Heping; Gu, Shubing; Zhou, Qunhui; Zhang, Shulan; Liu, Pengzni; Zhang, Junyi.

1990-01-01

A total of 160 patients of two hospitals received 192 DSA examinations with different contrast administrations, and techniques of performing DSA were analyzed, compared, and evaluated with reference to the literature. It was concluded that (1) the peripheral injection of contrast material for IVDSA via cannula is simpler than that via a short catheter, but the incidences of contrast extravasation in both cases are higher than with central injection. (2) Both the lower part of the superior vena cava and the right atrial cavity are safe sites for central injection. With central injection for IVDSA, the arterial iodine concentration is approximately double that of peripheral injection, and consistent high quality examinations of the intracranial vessels may be obtained. However, neither peripheral nor central injections can visualize the small vessels clearly. (3) IVDSA may be substituted for conventional angiography only in examinations of the aorta and its main branches. (4) IADSA is becoming a superior angiographic technique and its clinical application is increasing. In addition, means of avoiding contrast extravasation during IVDSA and the main points of selecting the optimal technique for DSA are described in this paper. (author)

Biogenic Emission Inventory System (BEIS)

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Biogenic Emission Inventory System (BEIS) estimates volatile organic compound (VOC) emissions from vegetation and nitric oxide (NO) emission from soils. Recent BEIS development has been restricted to the SMOKE system

Assessment of hemodynamic changes in patients with renal artery stenosis by means of the cine MR phase-contrast technique; Einstufung haemodynamischer Veraenderungen bei Nierenarterienstenosen mittels MR-Cine-Phasenkontrastflussmessungen

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Schoenberg, S.O.; Knopp, M.V.; Bock, M.; Essig, M.; Hawighorst, H.; Zuna, I.; Schad, L.; Kaick, G. van [Deutsches Krebsforschungszentrum, Heidelberg (Germany). Forschungsschwerpunkt Radiologische Diagnostik und Therapie; Kallinowski, F.; Allenberg, J.R. [Chirurgische Universitaetsklinik, Heidelberg (Germany). Sektion Gefaesschirurgie; Just, A. [Heidelberg Univ. (Germany). 1. Physiologisches Inst.

1997-08-01

Purpose: To evaluate the use of high-temporal resolution cine MR phase-contrast flow measurements for assessment of flow dynamics in renal artery stenosis (RAS). Material and methods: In a dog model, cine MR flow measurements were validated by comparing the MR flow data to an invasive transit-time ultrasound reference technique for different degrees of RAS. Cardiac-gated MR flow curves were recorded in 56 renal arteries of 28 patients with a temporal resolution of at least 32 ms. In all cases RAS was confirmed by digital subtraction angiography (DSA). Abnormalities of flow dynamics were assessed in the calculated flow curves using the MR parameters mean flow, maximum velocity, and time to systolic maximum. Results: By means of the MR blood flow paremeters high-grade stenoses (>50%, n=23) were detected with sensitivity of 100% and specificity of 94% with reference to DSA. The overall differentiation between stenoses (n=37) and non-stenosed vessels (n=19) revealed a sensitivity of 87% and a specificity of 100%. Conclusion: Analysis of cardiac-gated MR flow curves provides a non-invasive method to assess the hemodynamic significance of RAS and thus allows a functional evaluation in relation to the morphologic characteristics of the stenosis. (orig.) [Deutsch] Ziel der Untersuchung war die Beurteilung der Haemodynamik bei Nierenarterienstenosen mittels Cine-MR-Phasenkontrastflussmessungen. In einem Hundemodell wurde die Cine-MR-Flussmessung validiert, indem fuer unterschiedliche Stenosegrade Vergleichsmessungen mit einer invasiven Transitzeit-Ultraschallreferenztechnik durchgefuehrt wurden. EKG-getriggerte MR-Flusskurven wurden bei 28 Patienten in 56 Nierenarterien mit einer Zeitaufloesung von mindestens 32 ms aufgenommen. Alle Nierenarterienstenosen wurden mittels digitaler Subtraktionsangiographie gesichert. Stoerungen in der renalen Haemodynamik wurden anhand der berechneten MR-Flusskurven mit Hilfe der Parameter `Mittelfluss, `maximale Geschwindigkeit` und `Zeit

Die Bandscheibenprothese bei schmerzhafter Diskusdegeneration

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Ogon M

2004-01-01

Full Text Available Bandscheibenprothesen sind indiziert bei Patienten mit einer schmerzhaften Bandscheibendegeneration, einer sogenannten DDD (degenerative disc disease, bei gut erhaltenen Facettengelenken. Kontraindikationen stellen eine Instabilität, eine Spondylarthrose, eine spinale Stenose und eine Osteoporose dar. Bei 19 Patienten mit einem Follow-up von mindestens 12 Monaten fand sich eine durchschnittliche Verbesserung des Oswestry Disability Index von präoperativ 50,8 auf 19,8. Der SF-36 Score zur Erfassung der Lebensqualität besserte sich von 31,5 auf 48,8 (Physical Component Summary Score bzw. von 37,8 auf 44,5 (Mental Component Summary Score im 1-Jahres-Follow-up. Nachhaltige Komplikationen traten nicht auf. Bandscheibenprothesen können heute bei Patienten mit therapieresistenten Kreuzschmerzen als gute Alternative zu einer Wirbelfusion angesehen werden.

CO2-DSA in lower extremity veins: a clinical application

International Nuclear Information System (INIS)

Guo Jinhe; Teng Gaojun; Zhu Guangyu; Liu Zhensheng; Li Guozhao; Ding Huijuan; Shen Zhiping; He Shicheng; Deng Gang; Fang Wen

2005-01-01

Objective: To explore the feasibility and usefulness of carbon dioxide digital subtraction angiography (CO 2 -DSA) in deep veins of lower extremity via the dorsal is pedis vein. Methods: CO 2 -DSA in lower extremity veins was performed in 15 patients (15 limbs affected, male 9, female 6) by injection of CO 2 via the dorsal is pedis vein. Among them, 8 patients were suspected with deep venous thrombosis (DVT), 6 patients with saphena magna dilation, and 1 patient with a follow-up after thrombolysis due to DVT. Results: Excellent image was obtained in 12 cases, which showed branches of the venous system clearly, as well as the details of DVT. Good image was obtained in 2 cases. Technical failure was encountered in one patient due to inaccessible puncture veins. Mild discomfort (transient pain at the percutaneous site) during the procedure was demonstrated in 11 patients. There was no severe side effects or complications in this series. Conclusion: CO 2 -DSA in lower extremity veins is feasible and safe, the preliminary result is satisfactory. (authors)

DSA findings and bronchial arterial embolization of bronchiectasis with massive hemoptysis

International Nuclear Information System (INIS)

Xu Guobin; Liu Junfang; Hu Jinxiang; Long Qingyun

2008-01-01

Objective: To explore DSA findings curative measures and effects of bronchial arterial embolization (BAE)of bronchiectasis with massive hemoptysis. Methods: 35 patients with massive hemoptysis due to bronchiectasis were performed selective bronchial arterial DSA and BAE referring to image data of chest plain film and CT. Embolic materials were polyvinyl alcohol (PVA)and/or gelatinum sponge particles. Curative effects were followed-up for 3 months to 3 years. Results: (1)DSA revealed bronchial artery as being the only abnormal vessel accounted for 74.3%, bronchial artry combined with nonbronchial systemic artery as 22.9% and only non-bronchial artery involved 2.9%. Abnormal vessel number was 1-5 (mean 1.8) per case; Direct and indirect bleeding sign was displayed as 25.7% and 100% respectively. (2)Curative and embolization effects were shown as 61 target vessels of 34 patients being embolized and total effective rate reaching 85.3%; of which 16 cases were adopted super-selective technique, 1 case was failure of stopping bleeding for two times within 3 days, 4 cases recurred within 3 months and 2 cases recurred over 3 months; with recurrent rate of 20.6%, but no serious complications such as spinal cord injury. Conclusions: DSA examination and selective BAE of bronchiectasis with massive hemoptysis could provide high positive angiographic features and reliable curative effect. (authors)

Hepatic VX2 tumor after portal vein occlusion in rabbits: evaluation with DSA

International Nuclear Information System (INIS)

Qi Yueyong; Zou Liguang; Dai Shuhua; Zhang Qichuan; Chen Lin; Huang Xiaobing; Huan Guangqiang

2006-01-01

Objective: To study the value of DSA for hepatic vascular anatomy, and to evaluate the efficacy of portal vein occlusion in rabbits with hepatic VX2 tumor. Methods: Twenty New Zealand white rabbits were randomly divided into two groups with 10 in each group, including test group A and positive control group B of ham operation. For the test group A, portal branch ligation (PBL) was performed for the left external branch after 3 weeks of the tumor implantation to the left external lobe. Two weeks later, the DSA of hepatic artery and portal vein were performed in all of the rabbits. Results: The total displaying effectiveness of the branches of hepatic artery by DSA was better than that by vascular perfusion. There was hypovascular blood supply to hepatic artery implantation of the tumor in the test group A, comparing with that of the group B. Conclusion: DSA can clearly display special details of the hepatic vascular anatomy in rabbits, and play an important role in post-procedural evaluation of the portal vein occlusion in rabbits. (authors)

Benign Prostatic Hyperplasia: Cone-Beam CT in Conjunction with DSA for Identifying Prostatic Arterial Anatomy.

Science.gov (United States)

Wang, Mao Qiang; Duan, Feng; Yuan, Kai; Zhang, Guo Dong; Yan, Jieyu; Wang, Yan

2017-01-01

Purpose To describe findings in prostatic arteries (PAs) at digital subtraction angiography (DSA) and cone-beam computed tomography (CT) that allow identification of benign prostatic hyperplasia and to determine the value added with the use of cone-beam CT. Materials and Methods This retrospective single-institution study was approved by the institutional review board, and the requirement for written informed consent was waived. From February 2009 to December 2014, a total of 148 patients (mean age ± standard deviation, 70.5 years ± 14.5) underwent DSA of the internal iliac arteries and cone-beam CT with a flat-detector angiographic system before they underwent prostate artery embolization. Both the DSA and cone-beam CT images were evaluated by two interventional radiologists to determine the number of independent PAs and their origins and anastomoses with adjacent arteries. The exact McNemar test was used to compare the detection rate of the PAs and the anastomoses with DSA and with cone-beam CT. Results The PA anatomy was evaluated successfully by means of cone-beam CT in conjunction with DSA in all patients. Of the 296 pelvic sides, 274 (92.6%) had only one PA. The most frequent PA origin was the common gluteal-pudendal trunk with the superior vesicular artery in 118 (37.1%), followed by the anterior division of the internal iliac artery in 99 (31.1%), and the internal pudendal artery in 77 (24.2%) pelvic sides. In 67 (22.6%) pelvic sides, anastomoses to adjacent arteries were documented. The numbers of PA origins and anastomoses, respectively, that could be identified were significantly higher with cone-beam CT (301 of 318 [94.7%] and 65 of 67 [97.0%]) than with DSA (237 [74.5%] and 39 [58.2%], P < .05). Cone-beam CT provided essential information that was not available with DSA in 90 of 148 (60.8%) patients. Conclusion Cone-beam CT is a useful adjunctive technique to DSA for identification of the PA anatomy and provides information to help treatment planning

Survey of DSA-certified digital repositories : Report on the findings in a survey of all DSA-certified digital repositories on investments in and benefits of acquiring the Data Seal of Approval (DSA)

NARCIS (Netherlands)

Waterman, Kees-Jan; Sierman, Barbara

2016-01-01

The Data Seal of Approval (DSA) has been in use as a certification instrument for trustworthy digital repositories (TDRs) since 2010. By March 2016 some 50 repositories had applied successfully for the seal. Whereas some organizations and repositories have published about their own experiences in

Value of digital angiography as a substitute for film angiography in comparison with DSA

International Nuclear Information System (INIS)

Langer, M.; Mitsch, E.; Zwicker, C.; Scholz, A.; Felix, R.; Langer, R.

1988-01-01

The authors performed a prospective study to evaluate whether digital angiography (DA) can provide diagnostic image quality to reduce the need for film studies. The study is based on more than 100 arterial DSA examinations that were intra- and interindividually compared with the DA studies of the same arteries. It was demonstrated that DA with the same quantity of contrast medium as DSA is diagnostic in 80% of cases for abdominal, pelvic, and femoral arteries and in 85% for brachial arteries but in only 56% for carotid arteries if an aortic arch injection is performed. For all examinations, image quality with DSA was excellent in 86%, good in 9%, and diagnostic in 5%, with DA, it was excellent in 5%, good in 49%, diagnostic in 22%, and bad in 24% (90% of these were supraaortic studies). The results of this study indicate that it is worth trying a DA study when DSA is nondiagnostic because of artifacts, if a selective intraarterial contrast medium injection can be performed

Precise Point Positioning with the BeiDou Navigation Satellite System

Directory of Open Access Journals (Sweden)

Min Li

2014-01-01

Full Text Available By the end of 2012, China had launched 16 BeiDou-2 navigation satellites that include six GEOs, five IGSOs and five MEOs. This has provided initial navigation and precise pointing services ability in the Asia-Pacific regions. In order to assess the navigation and positioning performance of the BeiDou-2 system, Wuhan University has built up a network of BeiDou Experimental Tracking Stations (BETS around the World. The Position and Navigation Data Analyst (PANDA software was modified to determine the orbits of BeiDou satellites and provide precise orbit and satellite clock bias products from the BeiDou satellite system for user applications. This article uses the BeiDou/GPS observations of the BeiDou Experimental Tracking Stations to realize the BeiDou and BeiDou/GPS static and kinematic precise point positioning (PPP. The result indicates that the precision of BeiDou static and kinematic PPP reaches centimeter level. The precision of BeiDou/GPS kinematic PPP solutions is improved significantly compared to that of BeiDou-only or GPS-only kinematic PPP solutions. The PPP convergence time also decreases with the use of combined BeiDou/GPS systems.

Precise point positioning with the BeiDou navigation satellite system.

Science.gov (United States)

Li, Min; Qu, Lizhong; Zhao, Qile; Guo, Jing; Su, Xing; Li, Xiaotao

2014-01-08

By the end of 2012, China had launched 16 BeiDou-2 navigation satellites that include six GEOs, five IGSOs and five MEOs. This has provided initial navigation and precise pointing services ability in the Asia-Pacific regions. In order to assess the navigation and positioning performance of the BeiDou-2 system, Wuhan University has built up a network of BeiDou Experimental Tracking Stations (BETS) around the World. The Position and Navigation Data Analyst (PANDA) software was modified to determine the orbits of BeiDou satellites and provide precise orbit and satellite clock bias products from the BeiDou satellite system for user applications. This article uses the BeiDou/GPS observations of the BeiDou Experimental Tracking Stations to realize the BeiDou and BeiDou/GPS static and kinematic precise point positioning (PPP). The result indicates that the precision of BeiDou static and kinematic PPP reaches centimeter level. The precision of BeiDou/GPS kinematic PPP solutions is improved significantly compared to that of BeiDou-only or GPS-only kinematic PPP solutions. The PPP convergence time also decreases with the use of combined BeiDou/GPS systems.

The internal carotid artery stenosis or occlusion. The evaluation for the posterior communicating artery on DSA and MRA

International Nuclear Information System (INIS)

Zhao Yunhui; Gao Xinjiang; Ma Zhubin; Xu Yikai

2003-01-01

Objective: To study the changes of the posterior communicating artery in patients with internal carotid artery (ICA) severe stenosis or occlusion on digital subtract angiography (DSA) and magnetic resonance angiography (MRA). Methods: DSA or MRA findings were analyzed in 74 patients with ICA stenosis or occlusion and in 120 persons selected in the control group, who were unremarkable on cerebral DSA or MRA. Results: On DSA, the presence rate of ipsilateral posterior communicating artery (PCoA) between the study group and the control group had no significant difference; on MRA the rate in the study group was significantly higher than the control group (P 0.05). In the study group, the presence rate of PCoA on DSA was significantly higher than that on MRA (P 0.05). The presence rate of PCoA shown no significant difference between the cases with unilateral ICA involved and cases with bilateral ICA involved. Conclusion: The posterior communicating artery is very important to the patients with the internal carotid artery stenosis or occlusion. Its dilatation on DSA and MRA or appearance on MRA shows its compensation. DSA is valuable in the evaluation of the posterior communicating artery. MRA is a noninvasive and functional imaging method for evaluation the posterior communicating artery

Mehrfacheffekt-Feuchtluftdestillation bei Umgebungsdruck

OpenAIRE

Müller-Holst, Hendrik

2007-01-01

Ein neuartiges Verfahren zur Feuchtluftdestillation mittels Verdunstung und Kondensation in einer einzigen Kammer wurde im Rahmen der Arbeit umfassend analysiert. Das Verfahren arbeitet bei Umgebungsdruck; der dadurch bei Temperaturen unter dem Siedepunkt verringerte Stoffübergang wird durch große Austauschflächen mit hoher Packungsdichte kompensiert. Der Transport der im Verdunster beladenen Feuchtluft zum Kondensator erfolgt innerhalb einer optimierten geometrischen Anordnung der Baueinheit...

Electrochemical treatment of tannery wastewater using DSA electrodes

International Nuclear Information System (INIS)

Costa, Carla Regina; Botta, Clarice M.R.; Espindola, Evaldo L.G.; Olivi, Paulo

2008-01-01

In this work we studied the electrochemical treatment of a tannery wastewater using dimensionally stable anodes (DSA) containing tin, iridium, ruthenium, and titanium. The electrodes were prepared by thermal decomposition of the polymeric precursors. The electrolyses were performed under galvanostatic conditions, at room temperature. Effects of the oxide composition, current density, and effluent conductivity were investigated, and the current efficiency was calculated as a function of the time for the performed electrolyses. Results showed that all the studied electrodes led to a decrease in the content of both total phenolic compounds and total organic carbon (TOC), as well as lower absorbance in the UV-vis region. Toxicity tests using Daphnia similis demonstrated that the electrochemical treatment reduced the wastewater toxicity. The use of DSA type electrodes in the electrochemical treatment of tannery wastewater proved to be useful since it can promote a decrease in total phenolic compounds, TOC, absorbance, and toxicity

Electrochemical treatment of tannery wastewater using DSA electrodes

Energy Technology Data Exchange (ETDEWEB)

Costa, Carla Regina [Departamento de Quimica, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Universidade de Sao Paulo, CEP 14049-901 Ribeirao Preto, SP (Brazil); Botta, Clarice M.R.; Espindola, Evaldo L.G. [Nucleo de Estudos em Ecossistemas Aquaticos, Centro de Recursos Hidricos e Ecologia Aplicada, Escola de Engenharia de Sao Carlos, Universidade de Sao Paulo, CP 292, CEP 13560-970 Sao Carlos, SP (Brazil); Olivi, Paulo [Departamento de Quimica, Faculdade de Filosofia, Ciencias e Letras de Ribeirao Preto, Universidade de Sao Paulo, CEP 14049-901 Ribeirao Preto, SP (Brazil)], E-mail: olivip@ffclrp.usp.br

2008-05-01

In this work we studied the electrochemical treatment of a tannery wastewater using dimensionally stable anodes (DSA) containing tin, iridium, ruthenium, and titanium. The electrodes were prepared by thermal decomposition of the polymeric precursors. The electrolyses were performed under galvanostatic conditions, at room temperature. Effects of the oxide composition, current density, and effluent conductivity were investigated, and the current efficiency was calculated as a function of the time for the performed electrolyses. Results showed that all the studied electrodes led to a decrease in the content of both total phenolic compounds and total organic carbon (TOC), as well as lower absorbance in the UV-vis region. Toxicity tests using Daphnia similis demonstrated that the electrochemical treatment reduced the wastewater toxicity. The use of DSA type electrodes in the electrochemical treatment of tannery wastewater proved to be useful since it can promote a decrease in total phenolic compounds, TOC, absorbance, and toxicity.

Efficacy of balloon temporary occlusion and intraoperative DSA in surgically difficult aneurysm

International Nuclear Information System (INIS)

Ezura, Masayuki; Mizoi, Kazuo; Yoshimoto, Takashi; Takahashi, Akira.

1993-01-01

A digital subtraction angiographic (DSA) apparatus has been installed in one of our operating rooms since April 1987. We performed intraoperative DSA in 42 aneurysmal surgeries in 38 patients and balloon temporary occlusion in 33 surgeries. The aneurysm was on an internal carotid artery in 26 cases and on the vertebro-basilar system in 16. A heparin-coated catheter (Anthron, Toray, Tokyo), 6 french in diameter, was inserted transfemorally and was put in a parent artery under general anesthesia. A balloon was temporarily inflated to determine inflation volume. The balloon catheter was soon deflated and was drawn back into the introducing catheter to avoid developing microembolus. The patients were not systemically heparinized but the introducing catheters were slowly flushed with heparinized saline during operation. Then a craniotomy was carried out. Next DSA was performed when temporary occlusion or confirmation of clipping was necessary. In cases of balloon temporary occlusion, the operating field was not obstructed as it is when a temporary clip is used, despite adequate flow reduction of the parent artery. After DSA for confirmation of clipping adjustment of it was performed in 12 cases out of 42. No complications occurred due to use of an introducing or a balloon catheter. We conclude that combined intravascular and neurosurgical approach, particularly for the large aneurysms with the difficulty of proximal control, can be a useful method of treatment. (author)

Digital Subtraction Angiography (DSA) "Road Map": An Angiographic Tool

Science.gov (United States)

Turski, P. A.; Stieghorst, M. F.; Strother, C. M.; Crummy, A. B.; Lieberman, R. P.; Mistretta, C. A.

1982-12-01

Continuous Digital subtraction combined with intraarterial injections of contrast medium permits the display of arterial structures during real time fluoroscopy. This DSA "road map" facilitates selective catheterization and has proved useful in interventional procedures.

[2011 Shanghai customer satisfaction report of DSA/X-ray equipment's after-service].

Science.gov (United States)

Li, Bin; Qian, Jianguo; Cao, Shaoping; Zheng, Yunxin; Xu, Zitian; Wang, Lijun

2012-11-01

To improve the manufacturer's medical equipment after-sale service, the fifth Shanghai zone customer satisfaction survey was launched by the end of 2011. The DSA/X-ray equipment was setup as an independent category for the first time. From the survey we can show that the DSA/X-ray equipment's CSI is higher than last year, the customer satisfaction scores of preventive maintenance and service contract are lower than others, and CSI of local brand is lower than imported brand.

A comparison between DART-MS and DSA-MS in the forensic analysis of writing inks.

Science.gov (United States)

Drury, Nicholas; Ramotowski, Robert; Moini, Mehdi

2018-05-23

Ambient ionization mass spectrometry is gaining momentum in forensic science laboratories because of its high speed of analysis, minimal sample preparation, and information-rich results. One such application of ambient ionization methodology includes the analysis of writing inks from questioned documents where colorants of interest may not be soluble in common solvents, rendering thin layer chromatography (TLC) and separation-mass spectrometry methods such as LC/MS (-MS) impractical. Ambient ionization mass spectrometry uses a variety of ionization techniques such as penning ionization in Direct Analysis in Real Time (DART), and atmospheric pressure chemical ionization in Direct Sample Analysis (DSA), and electrospray ionization in Desorption Electrospray Ionization (DESI). In this manuscript, two of the commonly used ambient ionization techniques are compared: Perkin Elmer DSA-MS and IonSense DART in conjunction with a JEOL AccuTOF MS. Both technologies were equally successful in analyzing writing inks and produced similar spectra. DSA-MS produced less background signal likely because of its closed source configuration; however, the open source configuration of DART-MS provided more flexibility for sample positioning for optimum sensitivity and thereby allowing smaller piece of paper containing writing ink to be analyzed. Under these conditions, the minimum sample required for DART-MS was 1mm strokes of ink on paper, whereas DSA-MS required a minimum of 3mm. Moreover, both techniques showed comparable repeatability. Evaluation of the analytical figures of merit, including sensitivity, linear dynamic range, and repeatability, for DSA-MS and DART-MS analysis is provided. To the forensic context of the technique, DART-MS was applied to the analysis of United States Secret Service ink samples directly on a sampling mesh, and the results were compared with DSA-MS of the same inks on paper. Unlike analysis using separation mass spectrometry, which requires sample

Progress of BeiDou time transfer at NTSC

Science.gov (United States)

Guang, Wei; Dong, Shaowu; Wu, Wenjun; Zhang, Jihai; Yuan, Haibo; Zhang, Shougang

2018-04-01

Time transfer using global navigation satellite system (GNSS) is a primary method of remote atomic clock comparisons. As of today, there are four operational GNSS systems, namely GPS, GLONASS, Galileo and BeiDou Navigation Satellite System (BDS or BeiDou). All of them can continuously provide position, navigation and time services. This paper mainly focuses on the progress of BeiDou time transfer at the National Time Service Center, Chinese Academy of Sciences (NTSC). In order to realize the BeiDou common view (CV) time comparison, we developed the Rinex2CGGTTS software according to the guidelines of the Common GNSS Generic Time Transfer Standard, Version 2E (CGGTTS V2E). By comparing the solutions of the Rinex2CGGTTS software to the solutions of the sbf2cggtts software provided by the manufacturer of our multi-GNSS receiver, we found the sbf2cggtts (version 1.0.5) solutions contained biases in measurements to different BeiDou satellites. The biases are most likely caused by sbf2cggtts’ timing group delay corrections in data processing. The noise of the observation data is analyzed by code multipath and common clock difference. Finally, the BeiDou CV results are compared to the GPS/GLONASS/Galileo CV results between NTSC and three European UTC(k) laboratories, including Royal Observatory of Belgium (ORB), Real Institute y Observatory de la Armada (ROA), Research Institutes of Sweden (RISE or SP). For the comparisons of each baseline, we aligned the BeiDou/Galileo/GLONASS links to the calibrated GPS link with the double-difference method. The results show that the performance of BeiDou CV is correlated to the number of BeiDou satellites available in common view. With the current BeiDou constellation, the standard deviation of the differences between all BeiDou CV satellites averaging result and the GPS PPP result is 2.03 ns, 2.90 ns and 4.06 ns for ORB-NTSC, SP-NTSC and ROA-NTSC links respectively.

Somatic and genetic radiation exposure of the patient in digital subtraction angiography (DSA)

International Nuclear Information System (INIS)

Neufang, K.F.R.; Ewen, K.

1986-01-01

The somatic and genetic radiation exposure of patients undergoing Digital Subtraction Angiography (DSA) and traditional Film Arteriography (FA) of cranial, cervical, thoracic and abdominal vascular territories are compared. The radiation doses absorbed within the critical organs - red bone marrow, lung, thyroid gland and female breast - and in the gonads were measured using an anthropomorphic Alderson phantom. A Somatic Dose Index was calculated in order to estimate the somatic radiation risk. The somatic radiation exposure depends upon the location of the critical organs with respect to the entrance site of the x-ray beam, and can be reduced by an appropriate choice of the angiographic projection. Under this condition, the radiation exposure of the patient during DSA can be lower than during FA. For renal DSA an a.p. projection, the use of an abdominal compression device and careful caudal shielding of the field are advocated. (orig.)

DSA diagnosis and embolization therapy of gastrointestinal hemorrhage

International Nuclear Information System (INIS)

Zhou Ruming; Qiu Shuibo; Liu Minhua; Yang Huijun; Zhuang Shaoyu

2006-01-01

Objective: To evaluate the effect of digital subtraction angiography and transcatheter embolization for gastrointestinal hemorrhage. Methods: Twenty patients with gastrointestinal hemorrhage received celiac arteries, superior mesenteric arteries and inferior mesenteric arteries angiography. Superselective angiography were performed when the arteries were suspicious by clinic or angiogrraphy. Ten patients with definite diagnosis and manifestation of hemorrhagic arteries by angiography were embolized after superselective catheterization with gelfoam particles, gelfoam particles and coils, polyvinyl alcohol particles. Results: The positive signs were observed in 13 cases. The DSA features including contrast medium accumulation in the gastrointestinal tract outside vascular, aneurysm, tumorous vascularization and staining, artery affect and local vasospasm. The bleedings were stopped immediately in 8 patients. No rebleeding and intestinal ischaemia or necrosis were observed in 30 days. One patient died in the second day after embolization from multiple organ failure. Rebleeding occurred 3 days after embolization in another patient, and was recovered after surgical operation. Conclusion: DSA is more effective for the diagnosis of gastrointestinal vascular malformation and tumors complicating acute bleeding. Transcatheter embolization is effective and safe to control the hemorrhage. (authors)

3D DSA findings of uterine artery and its optimal projection position

International Nuclear Information System (INIS)

Lu Weifu; Zhang Aiwu; Zhou Chunze; Lu Dong; Xiao Jingkun; Wang Weiyu; Zhang Xingming; Zhang Zhengfeng; Hou Changlong

2011-01-01

Objective: to observe the origin site, anatomic features of uterine artery with 3D DSA and to discuss the optimal projection position in order to improve the success rate of super-selective catheterization of uterine artery. Methods: Prospective pelvic angiography was performed in 42 adult females (a total of 84 uterine arteries). 3D DSA was carried out with 206 ° rotation. 3D reconstruction of the obtained images was performed and the angiographic manifestations of the uterine artery were analyzed. The optimal projection position for the displaying of uterine artery was discussed. The quality of images obtained with the projection angle of 15 °-25 °, 25 °-35 ° and 35 °-45 ° was determined and the results were compared with each other. Results: The orifices of all 84 uterine arteries could be well demonstrated on 3D DSA images. The uterine artery was originated from the anterior trunk of internal iliac artery (n=58, 69%), from main stem of internal iliac artery (n=16, 19.1%), from internal pudenda artery (n=8, 9.5%) and from inferior gluteal artery (n=2, 2.4%). The best projection position to show the opening and route of the uterine artery was contralateral oblique view of 25-35 degrees (P<0.05). Conclusion: 3D DSA can clearly display the anatomy of the uterine artery, which is very helpful for the management of super-selective catheterization of uterine artery. The optimal projection position for uterine artery is contralateral oblique view of 25-35 degrees. (authors)

The placement of naso-jejunal feeding tube under DSA guidance: its technology and skills

International Nuclear Information System (INIS)

Song Laichang; Wang Wenhui; Li Fenqiang; Su Dongjun; Li Bo

2009-01-01

Objective: To retrospectively analyze and summarize the manipulation and skills of the placement of naso-jejunal feeding tube under DSA guidance. Methods: After performing the spraying anesthesia of nasopharynx, the naso-jejunal feeding tube, with the help of guide wire and under DSA guidance, was placed into the proximal jejunum by passing it through the nose, pharynx, esophagus, stomach, pylorus and duodenum in order. The procedure was employed in 441 cases. Results: The mean time for performing the procedure was within five minutes. The procedure was successfully accomplished in all 441 cases and no complications occurred in this series. Conclusion: Under DSA guidance the placement of naso- jejunal feeding tube can be safely and quickly carried out with high successful rate and less sufferings to patient. It is worth popularizing this technique in clinical practice. (authors)

Application of DSA and ultrasonic blood rheography (Doppler) to benign paroxysmal positional vertigo

International Nuclear Information System (INIS)

Fujita, Nobuya; Wada, Yoshiro; Suzumura, Shigeo; Matsunaga, Takashi

1990-01-01

Fourteen cases of benign paroxysmal positional vertigo (BPPV) were studied with cervical circulation using DSA and Doppler. DSA study showed 7 abnormal cases out of 10 cases of BPPV. The abnormal findings included 5 cases of stenosis and 5 cases of coiling and kinking in cervical vertebral arteries. Doppler study showed that vertebral a. and also carotid a. had low volume and high laterality of cervical blood circulation in parameter of flow and velocity. These findings suggest the cervical circulation disorder was one of background factors in pathogenesis of BPPV. (author)

Application of DSA and ultrasonic blood rheography (Doppler) to benign paroxysmal positional vertigo

Energy Technology Data Exchange (ETDEWEB)

Fujita, Nobuya; Wada, Yoshiro; Suzumura, Shigeo; Matsunaga, Takashi (Nara Medical Univ., Kashihara (Japan))

1990-03-01

Fourteen cases of benign paroxysmal positional vertigo (BPPV) were studied with cervical circulation using DSA and Doppler. DSA study showed 7 abnormal cases out of 10 cases of BPPV. The abnormal findings included 5 cases of stenosis and 5 cases of coiling and kinking in cervical vertebral arteries. Doppler study showed that vertebral a. and also carotid a. had low volume and high laterality of cervical blood circulation in parameter of flow and velocity. These findings suggest the cervical circulation disorder was one of background factors in pathogenesis of BPPV. (author).

Osteoporose bei Spondylitis ankylosans - Einfluß von Lebensgewohnheiten

Directory of Open Access Journals (Sweden)

Aglas F

2004-01-01

Full Text Available Krankheitsbedingte Artefakte können bei der SpA (Spondylitis ankylosans; Mb. Bechterew die Sensitivität einer Knochendichtemessung im Lumbalbereich beeinträchtigen. Das bei dieser rheumatischen Erkrankung bekannte Osteoporoserisiko ist neben genetischen Faktoren und Entzündungsmechanismen auch von verschiedenen exogenen Einflüssen abhängig. An 47 SpA-Patienten wurde mittels DEXA eine vergleichende Knochendichtemessung (BMD an der Hüfte (Schenkelhals und Ward'sches Dreieck sowie im Bereich der Wirbelsäule (L1-L4 vorgenommen. Zusätzlich erfolgte eine Erhebung der Lebens-Ernährungsgewohnheiten der SpA-Patienten in bezug auf die BMD, um exogene Einflüsse erfassen zu können. Die Knochendichtemessungen ergaben an der LWS wesentlich häufiger eine BMD im Normbereich als am proximalen Femur. Besonders deutliche Unterschiede traten im höheren Lebensalter auf, bei dem aufgrund von Kalzifizierungsvorgängen und Syndesmophyten an der LWS fälschlicherweise eine Dichtezunahme vorgetäuscht wird. Es kann daher bei SpA empfohlen werden, die wesentlich sensitivere Dichtemessung am Schenkelhals durchzuführen. Die über einen Zeitraum von 3 Jahren beobachteten, signifikant erhöhten, medianen CRP-Spiegel zeigen, daß eine permanente Aktivierung von Entzündungsprozessen bei SpA auch einen negativen Faktor betreffend des Knochenmasseverlustes darstellt. Die Analyse der Lebensgewohnheiten ergab, daß SpA-Patienten mit normaler BMD ausnahmslos regelmäßig kalziumreiche Nahrungsmittel zu sich nehmen; bei verminderter BMD wurde in der Mehrheit ein fehlender Konsum an Milchprodukten beobachtet. Leider war auch mit abnehmender BMD eine Verminderung der bei SpA empfohlenen Bewegungsübungen festzustellen. Aufgrund der Resultate ergibt sich eine generelle Empfehlung zu regelmäßigen Bewegungsübungen plus Osteoporosediät bei allen Bechterew-Patienten.

Overcoming the Challenges of BeiDou Receiver Implementation

Directory of Open Access Journals (Sweden)

Mohammad Zahidul H. Bhuiyan

2014-11-01

Full Text Available Global Navigation Satellite System (GNSS-based positioning is experiencing rapid changes. The existing GPS and the GLONASS systems are being modernized to better serve the current challenging applications under harsh signal conditions. These modernizations include increasing the number of transmission frequencies and changes to the signal components. In addition, the Chinese BeiDou Navigation Satellite system (BDS and the European Galileo are currently under development for global operation. Therefore, in view of these new upcoming systems the research and development of GNSS receivers has been experiencing a new upsurge. In this article, the authors discuss the main functionalities of a GNSS receiver in view of BDS. While describing the main functionalities of a software-defined BeiDou receiver, the authors also highlight the similarities and differences between the signal characteristics of the BeiDou B1 open service signal and the legacy GPS L1 C/A signal, as in general they both exhibit similar characteristics. In addition, the authors implement a novel acquisition technique for long coherent integration in the presence of NH code modulation in BeiDou D1 signal. Furthermore, a simple phase-preserved coherent integration based acquisition scheme is implemented for BeiDou GEO satellite acquisition. Apart from the above BeiDou-specific implementations, a novel Carrier-to-Noise-density ratio estimation technique is also implemented in the software receiver, which does not necessarily require bit synchronization prior to estimation. Finally, the authors present a BeiDou-only position fix with the implemented software-defined BeiDou receiver considering all three satellite constellations from BDS. In addition, a true multi-GNSS position fix with GPS and BDS systems is also presented while comparing their performances for a static stand-alone code phase-based positioning.

BEI Resource Repository

Data.gov (United States)

U.S. Department of Health & Human Services — BEI Resources provides reagents, tools and information for studying Category A, B, and C priority pathogens, emerging infectious disease agents, non-pathogenic...

Gadolinium-DTPA (Magnevist) as a contrast medium for arterial DSA

International Nuclear Information System (INIS)

Schild, H.H.; Weber, W.; Boeck, E.; Mildenberger, P.; Strunk, H.; Dueber, C.; Grebe, P.; Schadmand-Fischer, S.; Thelen, M.

1994-01-01

16 DSA investigations using intra-arterial Gd-DTPA were performed on 12 patients. The contrast medium was administered either as a 0.5 molar gadolinium solution (commercially available) or diluted with distilled water to a 0.2 -0.4 molar gadolinium solution. The injection was made either by pressure injector or by hand. The aortic arch, abdominal aorta and pelvic and lower limb arteries were examined. 14 of the 16 procedures were diagnostically adequate, but compared with iodinated contrast materials, contrast was less marked. There were no cardiovascular, neurological or allergic side effects. Three patients suffered a feeling of heat and one patient had mild pain during the injection. Even large volumes rapidly injected (up to 20 ml/s of the commercially available solution) were well tolerated. DSA with intra-arterial Gd-DTPA seems to be a suitable alternative for vascular imaging if iodine-containing contrast materials are contraindicated. (orig.) [de

Selective transcervical tubal recanalisation using DSA

International Nuclear Information System (INIS)

Kelekis, D.; Fezoulidis, I.; Petsas, T.; Tsapalira, A.; Kelekis, N.

1991-01-01

The results of selective transcervical tubal recanalisation by means of a catheter in 20 patients with tubal occlusions are reported and discussed. The advantages of tubal recanalisation under DSA are stressed. In 18 (90%) of the 20 patients treated, it was possible to recanalise at least one tube. Nine of these 18 women (50%) became pregnant during the period of observation, averaging 12 months. Selective transcervical recanalisation of obstructive tubes is a rapid, reliable, cheap and hardly invasive treatment of sterility, when compared with laparoscopy or laparotomy. In the majority of patients it makes surgery unnecessary. (orig.) [de

Indications for intra-arterial digital subtraction angiography (DSA) in vascular disease

International Nuclear Information System (INIS)

Neufang, K.F.R.; Friedmann, G.; Peters, P.E.; Moedder, U.

1983-01-01

Digital subtraction angiography (DSA), using a direct arterial route, diminishes the risk of the examination by reducing the contrast dose by about 75%, making the examination more rapid and making it less likely that catheters will have to be changed. At the same time superimposition is avoided, one of the advantages of selective catheterisation. In view of the low contrast dose, it is possible to carry out several examinations at one time and to use additional projections for intracranial and peripheral disease, thereby improving the diagnostic value of the examination. For certain problems, intra-arterial DSA is already able to replace conventional angiography. The small field size and poor spatial resolution still make conventional angiography necessary as the basic form of investigation in most other circumstances. (orig.) [de

Comparison of CO2 DSA and conventional angiography using non-ionic contrast media in lower extremity angiography

International Nuclear Information System (INIS)

Kim, Jae Kyu; Park, Sung Jae; Koh, Seok Wan; Seo, Jeong Jin; Kang, Heoung Keun; Chung, Hyon De

1994-01-01

The purpose of this study is to compare CO 2 DSA and nonionic contrast media angiography in respect to the quality of the opacification of collaterals and incidence of side-effects in peripheral occlusive arterial disease. Sixteen patients who were suspected to have peripheral occlusive arterial disease were performed angiography with nonionic contrast media and CO 2 at the same location with the same catheter. The causes of the lesions were atherosclerosis(n=7) and Buerger's disease(n=9). CO 2 DSA was compared with nonionic contrast media angiography in respect to the quality of image in the diagnosis of the lesions, opacifications of collaterals and side-effects. In atherosclerosis; quality of the images of CO 2 DSA was same as that of nonionic contrast media angiography in 6 patients and was poor in 1 patient; opacifications of collaterals of CO 2 DSA were same as that of nonionic contrast media angiography in 5 patients and was poor in 2 patients. In Buerger's disease; quality of the images of CO 2 DSA was same as that of nonionic contrast media angiography in 2 patients and was poor in 7 patients; opacifications of collaterals of CO 2 DSA were same as that of nonionic contrast media angiography in 1 patient and was poor in 8 patients. Leg pain was the only side-effect after CO 2 injection occurring in 4 out of 16 patients. CO 2 could be used as safe contrast media in patient with risk factors for nonionic contrast media and for diagnosis of the atherosclerosis in lower extremity. For the procedures such as vascular intervention requiring large amount of contrast media CO 2 could effectively replace nonionic contrast media

A Method for Estimating BeiDou Inter-frequency Satellite Clock Bias

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LI Haojun

2016-02-01

Full Text Available A new method for estimating the BeiDou inter-frequency satellite clock bias is proposed, considering the shortage of the current methods. The constant and variable parts of the inter-frequency satellite clock bias are considered in the new method. The data from 10 observation stations are processed to validate the new method. The characterizations of the BeiDou inter-frequency satellite clock bias are also analyzed using the computed results. The results of the BeiDou inter-frequency satellite clock bias indicate that it is stable in the short term. The estimated BeiDou inter-frequency satellite clock bias results are molded. The model results show that the 10 parameters of model for each satellite can express the BeiDou inter-frequency satellite clock bias well and the accuracy reaches cm level. When the model parameters of the first day are used to compute the BeiDou inter-frequency satellite clock bias of the second day, the accuracy also reaches cm level. Based on the stability and modeling, a strategy for the BeiDou satellite clock service is presented to provide the reference of our BeiDou.

Conventional renal angiography versus renal digital subtraction angiography (DSA) in the study of renovascular hypertension

International Nuclear Information System (INIS)

Essinger, A.; Morsier, B. de; Narbel, M.; Raimondi, S.

1988-01-01

A cost-benefit analysis comparing conventional renal angiography, IV and IA DSA and spot film cameras has been made in order to quantify the advantages and disadvantages of these techniques in screening for renal artery stenosis. DSA is the best modality of imaging, using very little films, easy to archive, with a spatial resolution inferior to conventional angiography but partially compensated by contrast resolution. The surface dose per image using a 512/512 matrix is two thirds less than a conventional film, giving thus an acceptable dose as long as technical personnel is well trained and thus the number of exposures is kept low. Spot film camera, due to its excellent spatial resolution, its low radiation dose and its low price, can also be used as a screening procedure but requires an arterial injection. DSA has furthermore the advantage of quantifying renal artery stenosis making future percutaneous transluminal angioplasty easier

Comparison of remnant size in embolized intracranial aneurysms measured at follow-up with DSA and MRA

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Serafin, Zbigniew; Strzesniewski, Piotr; Lasek, Wladyslaw [Nicolaus Copernicus University, Department of Radiology and Diagnostic Imaging, Collegium Medicum, Bydgoszcz (Poland); Beuth, Wojciech [University of Humanities and Economics in Wloclawek, Faculty of Health Sciences, Wloclawek (Poland)

2012-12-15

The possibility of recanalization and the need for retreatment are the most important limitations of intracranial aneurysm embolization. The purpose of the study was to compare the size of aneurysm remnants measured at follow-up with three-dimensional digital subtracted angiography (3D-DSA) and magnetic resonance angiography (MRA). Twenty-six aneurysms were found incompletely occluded in 72 consecutively examined patients at a follow-up after 3 months. The diameters and volume of aneurysm remnants were compared between 3D-DSA, time-of-flight MRA (TOF-MRA), contrast-enhanced TOF-MRA (CE-TOF-MRA), and contrast-enhanced MRA (CE-MRA) at 1.5 T. There was a significant correlation between remnant volumes calculated based on 3D-DSA and all MRA modalities. The intraobserver variability of the measurements ranged from 3.4 to 4.1 % and the interobserver variability from 5.8 to 7.3 %. There were no significant differences in the variability between the techniques. The mean residual filling volume ranged from 16.3 {+-} 19.0 mm{sup 3} in TOF-MRA to 30.5 {+-} 44.6 mm{sup 3} in 3D-DSA (P < 0.04). Significant differences were found in the volumes measured with 3D-DSA and CE-MRA as compared to TOF-MRA and CE-TOF-MRA (P < 0.01). There was a moderate significant correlation between the residual filling and the relative error of measurement in the case of TOF-MRA and CE-TOF-MRA. TOF-MRA seems to underestimate the size of aneurysm remnants detected at follow-up and should not be used as a sole imaging method to decide on re-embolization. (orig.)

Comparison of remnant size in embolized intracranial aneurysms measured at follow-up with DSA and MRA

International Nuclear Information System (INIS)

Serafin, Zbigniew; Strzesniewski, Piotr; Lasek, Wladyslaw; Beuth, Wojciech

2012-01-01

The possibility of recanalization and the need for retreatment are the most important limitations of intracranial aneurysm embolization. The purpose of the study was to compare the size of aneurysm remnants measured at follow-up with three-dimensional digital subtracted angiography (3D-DSA) and magnetic resonance angiography (MRA). Twenty-six aneurysms were found incompletely occluded in 72 consecutively examined patients at a follow-up after 3 months. The diameters and volume of aneurysm remnants were compared between 3D-DSA, time-of-flight MRA (TOF-MRA), contrast-enhanced TOF-MRA (CE-TOF-MRA), and contrast-enhanced MRA (CE-MRA) at 1.5 T. There was a significant correlation between remnant volumes calculated based on 3D-DSA and all MRA modalities. The intraobserver variability of the measurements ranged from 3.4 to 4.1 % and the interobserver variability from 5.8 to 7.3 %. There were no significant differences in the variability between the techniques. The mean residual filling volume ranged from 16.3 ± 19.0 mm 3 in TOF-MRA to 30.5 ± 44.6 mm 3 in 3D-DSA (P < 0.04). Significant differences were found in the volumes measured with 3D-DSA and CE-MRA as compared to TOF-MRA and CE-TOF-MRA (P < 0.01). There was a moderate significant correlation between the residual filling and the relative error of measurement in the case of TOF-MRA and CE-TOF-MRA. TOF-MRA seems to underestimate the size of aneurysm remnants detected at follow-up and should not be used as a sole imaging method to decide on re-embolization. (orig.)

Experimental research on local renal injury of dog with microwave ablation guided by DSA

International Nuclear Information System (INIS)

Lin Jianping; Xian Zhengyuan; Shi Rongshu; Zhang Gaofeng; Li Xianlang

2008-01-01

Objective: To explore the efficiency, complications and probability of preserving part renal function by local renal microwave ablation. Methods: The fresh pig renal pelvis full filled with 30% diatrizoate meglumine and the dogs kidney taken arterial pyelography were both ablated with microwave. Dogs were divided into three groups: measuring temperature after ablation group, single point ablation both on the two kidneys group and double points ablation on unilateral kidney group. In measuring temperature after ablation group, DSA and pathology were performed immediately after ablation. In the other groups, DSA with blood and urine samplings were taken for routine tests including renal function right after the ablation and 10 days later. Results: Experiment in vitro showed conspicuous renal pelvic contraction and convolution. The group under power rate of 70, 3 min produced urine leak easily. Preliminary test in vivo with DSA showed the disappearance of local kidney blood supply. The residual renal function was related to areas of necrosis. Acute stage pathology revealed acute renal cortex medulla and pelvic cells injury. DSA of chronic stage showed no change in size of the area of ablation. The blood supply of necrotic areas was not restored. The residual kidney possessed the excretion contrast medium with no urine leaks. Upper pole of right kidney adhered with adjacent tissue, together with thickened covering. Pathology revealed fibrous proliferation around the coagulative necrosis. Conclusion: Microwave ablation can inactivate the local renal tissue, and, effectively preserve the big blood vessels and function of residual kidney. No urine leaks occurred in chronic stage but easily to produce adhesions with adjacent tissue. (authors)

Gadofosveset-enhanced MR angiography of the pedal arteries in patients with diabetes mellitus and comparison with selective intraarterial DSA

International Nuclear Information System (INIS)

Roehrl, Boris; Kunz, Rainer Peter; Oberholzer, Katja; Pitton, Michael Bernhard; Dueber, Christoph; Kreitner, Karl-Friedrich; Neufang, Achim

2009-01-01

To compare gadofosveset-enhanced magnetic resonance angiography (MRA) of the pedal vasculature with selective intraarterial DSA. Eighteen patients with PAOD and type II diabetes were prospectively examined at 1.5 T. For contrast enhancement, 0.03 mmol/kg body weight gadofosveset was used. MR imaging consisted of dynamic and of high-resolution steady-state imaging. Selective digital subtraction angiography (DSA) was performed within 5 days and served as standard of reference. Image analysis was done by two observers. There were no differences between MRA and DSA regarding overall image quality. First-pass MRA detected significantly more patent vessel segments than did DSA (P < 0.001, kappa = 0.46). Interobserver agreement of MRA was very good with respect to the detection of patent vessel segments and the assessment of hemodynamically relevant stenoses (kappa = 0.97 and 0.89, respectively). Steady-state imaging depicted significantly more patent metatarsal arteries than did dynamic imaging, and delineated inflammatory complications including osteomyelitis, soft-tissue abscesses, and fistulas related to the diabetic foot. Gadofosveset-enhanced MRA of the pedal vasculature proved to be superior to DSA. It offered a long imaging time window, and allowed for better depiction of the pedal outflow. Steady-state imaging delineated inflammatory complications associated with the diabetic foot. (orig.)

Gadofosveset-enhanced MR angiography of the pedal arteries in patients with diabetes mellitus and comparison with selective intraarterial DSA

Energy Technology Data Exchange (ETDEWEB)

Roehrl, Boris; Kunz, Rainer Peter; Oberholzer, Katja; Pitton, Michael Bernhard; Dueber, Christoph; Kreitner, Karl-Friedrich [Johannes Gutenberg University Mainz, Department of Diagnostic and Interventional Radiology, Mainz (Germany); Neufang, Achim [Johannes Gutenberg University Mainz, Department of Cardiothoracic and Vascular Surgery, Mainz (Germany)

2009-12-15

To compare gadofosveset-enhanced magnetic resonance angiography (MRA) of the pedal vasculature with selective intraarterial DSA. Eighteen patients with PAOD and type II diabetes were prospectively examined at 1.5 T. For contrast enhancement, 0.03 mmol/kg body weight gadofosveset was used. MR imaging consisted of dynamic and of high-resolution steady-state imaging. Selective digital subtraction angiography (DSA) was performed within 5 days and served as standard of reference. Image analysis was done by two observers. There were no differences between MRA and DSA regarding overall image quality. First-pass MRA detected significantly more patent vessel segments than did DSA (P < 0.001, kappa = 0.46). Interobserver agreement of MRA was very good with respect to the detection of patent vessel segments and the assessment of hemodynamically relevant stenoses (kappa = 0.97 and 0.89, respectively). Steady-state imaging depicted significantly more patent metatarsal arteries than did dynamic imaging, and delineated inflammatory complications including osteomyelitis, soft-tissue abscesses, and fistulas related to the diabetic foot. Gadofosveset-enhanced MRA of the pedal vasculature proved to be superior to DSA. It offered a long imaging time window, and allowed for better depiction of the pedal outflow. Steady-state imaging delineated inflammatory complications associated with the diabetic foot. (orig.)

Assessment of chronic thromboembolic pulmonary hypertension by three-dimensional contrast-enhanced MR angiography - comparison with selective intraarterial DSA

International Nuclear Information System (INIS)

Kreitner, K.F.; Ley, S.; Kauczor, H.U.; Kalden, P.; Pitton, M.B.; Thelen, M.; Mayer, E.; Laub, G.

2000-01-01

Purpose: This study compares contrast-enhanced 3D-MR angiography (MRA) of the pulmonary arteries with selective intraarterial DSA in patients with chronic thromboembolic pulmonary hypertension. Materials and methods: 20 patients preoperatively underwent a contrast-enhanced 3D-MRA of the pulmonary arteries at 1.5 T using the phased-array body coil. For MRA, we used a 3D-Flash-sequence after bolus timing. 2 radiologists analyzed the acquired image material in consensus with respect to the detection of central thromboembolic material and the visualization of the pulmonary arterial tree. Finally, the MR angiograms were compared with selective DSA images using surgical findings as the definitive standard. Results: MRA demonstrated central thromboembolic material, vessel cut-offs and abnormal proximal-to-distal tapering in all patients. Compared to DSA, MRA depicted the pulmonary vessels up to the segmental level in all cases, it was inferior to DSA in delineation of the subsegmental arteries (sensitivity 87%, specificity 100%). The central beginning of the thromboembolic occlusions seen at MRA corresponded to the beginning of the deobliteration procedure during pulmonary thromboendarterectomy in every case. (orig.) [de

The DSA diagnosis, artery embolization combined with low dose of vasopressin infusion treatment for lower digestive tract hemorrhage

International Nuclear Information System (INIS)

Huang Guoxin; Dou Yongchong; Zhang Yanfang; Shen Xinying; Xu Jianmin

2005-01-01

Objective: To evaluate the clinical value of digital subtraction angiography (DSA) diagnosis and interventional treatment for lower digestive tract hemorrhage of unknown reasons. Methods: DSA was performed in 32 patients with unknown etiologic lower digestive tract hemorrhage. The locations and causes of hemorrhage were determined by angiography according to the demonstration of contrast medium extravasation, abnormal vasculature and tumor staining. Superselective arterial embolization was performed with retaining catheter of low dose vasopressin infusion for 12 hours of hemostasis. Results: Seventy-five percent of the lesions were identified by DSA with 2 cases of intestinal typhoid, 1 intestinal tuberculosis, 14 cases of vascular malformation and 7 cases of tumor. Hemostasis was succeeded in 20 of 24 patients. The rate of success was 83.3%. Conclusions: DSA and interventional therapy are of great value in diagnosing and treating patients with lower digestive tract hemorrhage of unknown reasons and even those undergone unsuccessful conservative treatment. Low dose vasopressin infusion through retained catheter is safe and efficient after superselective arterial embolization. (authors)

Phlebography of the upper extremity. Pt. 1. Technique and findings in 230 examinations; Die Phlebographie der oberen Extremitaet. T. 1. Technik und Befunde bei 230 Untersuchungen

Energy Technology Data Exchange (ETDEWEB)

Maas, R [Radiologische Klinik des Universitaets-Krankenhauses Hamburg-Eppendorf (Germany). Abt. Roentgendiagnostik; Nicolas, V [Radiologische Klinik des Universitaets-Krankenhauses Hamburg-Eppendorf (Germany). Abt. Roentgendiagnostik; Muegge-Hamann, U [Radiologische Klinik des Universitaets-Krankenhauses Hamburg-Eppendorf (Germany). Abt. Roentgendiagnostik; Steiner, P [Radiologische Klinik des Universitaets-Krankenhauses Hamburg-Eppendorf (Germany). Abt. Roentgendiagnostik

1995-01-01

We report on 230 phlebographic examinations in the shoulder arm region which were performed by conventional X-ray technique and/or digital subtraction angiography (DSA). The detailed method of examination as well as anatomical variants of the vessels are explained. The group of patients was analysed concerning its composition and was subdivided with regard to clinically relevant diagnoses. Contrary to statements in the literature, the number of pathological findings in men or women were equal. The main age was between 40 and 50 years. The brachial vein was found to be doubled so often that this might be accepted as a normal situation. Phlebographic examinations were performed in the right arm twice as often as in the left one. 172 primary examinations, more than 60% showed a pathological result. (orig.) [Deutsch] Es wird ueber 230 Phlebographien der Schulter-/Armregion berichtet, die bei 172 Patienten in konventioneller und/oder digitaler Technik (DSA) durchgefuehrt wurden. Die Untersuchungstechnik wird ebenso wie anatomische Gefaessvarianten dargestellt. Das Patientenkollektiv wurde sowohl hinsichtlich seiner Zusammensetzung analysiert als auch nach klinisch relevanten Diagnosegruppen hin aufgearbeitet. Entgegen den Literaturangaben waren Patienten mit pathologischen Armphlebographien gleichhaeufig maennlich oder weiblich. Der Altersgipfel lag zwischen 40 und 50 Jahren. Die V. brachialis war so haeufig doppelt angelegt, dass dieser Befund als Normsituation angesehen werden kann. Phlebographien wurden doppelt so oft am rechten als am linken Arm durchgefuehrt. Von 172 Erstuntersuchungen erbrachten mehr als 60% einen pathologischen Befund. (orig.)

Comparison of hepatic MDCT, MRI, and DSA to explant pathology for the detection and treatment planning of hepatocellular carcinoma

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Lauren M. Ladd

2016-12-01

Full Text Available Background/Aims The diagnosis and treatment plan for hepatocellular carcinoma (HCC can be made from radiologic imaging. However, lesion detection may vary depending on the imaging modality. This study aims to evaluate the sensitivities of hepatic multidetector computed tomography (MDCT, magnetic resonance imaging (MRI, and digital subtraction angiography (DSA in the detection of HCC and the consequent management impact on potential liver transplant patients. Methods One hundred and sixteen HCC lesions were analyzed in 41 patients who received an orthotopic liver transplant (OLT. All of the patients underwent pretransplantation hepatic DSA, MDCT, and/or MRI. The imaging results were independently reviewed retrospectively in a blinded fashion by two interventional and two abdominal radiologists. The liver explant pathology was used as the gold standard for assessing each imaging modality. Results The sensitivity for overall HCC detection was higher for cross-sectional imaging using MRI (51.5%, 95% confidence interval [CI]=36.2-58.4% and MDCT (49.8%, 95% CI=43.7-55.9% than for DSA (41.7%, 95% CI=36.2-47.3% (P=0.05. The difference in false-positive rate was not statistically significant between MRI (22%, MDCT (29%, and DSA (29% (P=0.67. The sensitivity was significantly higher for detecting right lobe lesions than left lobe lesions for all modalities (MRI: 56.1% vs. 43.1%, MDCT: 55.0% vs. 42.0%, and DSA: 46.9% vs. 33.9%; all P<0.01. The sensitivities of the three imaging modalities were also higher for lesions ≥2 cm vs. <2 cm (MRI: 73.4% vs. 32.7%, MDCT: 66.9% vs. 33.8%, and DSA: 62.2% vs. 24.1%; all P<0.01. The interobserver correlation was rated as very good to excellent. Conclusion The sensitivity for detecting HCC is higher for MRI and MDCT than for DSA, and so cross-sectional imaging modalities should be used to evaluate OLT candidacy.

Comparison of remnant size in embolized intracranial aneurysms measured at follow-up with DSA and MRA.

Science.gov (United States)

Serafin, Zbigniew; Strześniewski, Piotr; Lasek, Władysław; Beuth, Wojciech

2012-12-01

The possibility of recanalization and the need for retreatment are the most important limitations of intracranial aneurysm embolization. The purpose of the study was to compare the size of aneurysm remnants measured at follow-up with three-dimensional digital subtracted angiography (3D-DSA) and magnetic resonance angiography (MRA). Twenty-six aneurysms were found incompletely occluded in 72 consecutively examined patients at a follow-up after 3 months. The diameters and volume of aneurysm remnants were compared between 3D-DSA, time-of-flight MRA (TOF-MRA), contrast-enhanced TOF-MRA (CE-TOF-MRA), and contrast-enhanced MRA (CE-MRA) at 1.5 T. There was a significant correlation between remnant volumes calculated based on 3D-DSA and all MRA modalities. The intraobserver variability of the measurements ranged from 3.4 to 4.1 % and the interobserver variability from 5.8 to 7.3 %. There were no significant differences in the variability between the techniques. The mean residual filling volume ranged from 16.3 ± 19.0 mm(3) in TOF-MRA to 30.5 ± 44.6 mm(3) in 3D-DSA (P < 0.04). Significant differences were found in the volumes measured with 3D-DSA and CE-MRA as compared to TOF-MRA and CE-TOF-MRA (P < 0.01). There was a moderate significant correlation between the residual filling and the relative error of measurement in the case of TOF-MRA and CE-TOF-MRA. TOF-MRA seems to underestimate the size of aneurysm remnants detected at follow-up and should not be used as a sole imaging method to decide on re-embolization.

Comparison of X-ray radiation exposure during digital subtraction angiography (DSA) and multislice CT angiography (CTA)

International Nuclear Information System (INIS)

Bai, Mei; Liu, Bin; Zheng, Junzheng

2008-01-01

Full text: Purpose: To compare radiation risk during digital subtraction angiography (DSA) and CT angiography (CTA). Materials and methods: Eighty patients randomly divided into two groups of 40 patients each, were evaluated for coronary atherosclerotic heart disease with 64-slice spiral CT angiography and DSA respectively. For CTA group we divided patients into two subgroups: regular mode and ECG modulation mode. Matix of thermoluminescent dosimeters (TLDs) were placed on patients' skin surface during each examination to access peak skin dose (PSD). A male ART phantom was equipped with TLDs in six different positions to assess achievable organ dose. Effective dose was calculated by commercially available computer programs. Results: For DSA, PSD was 64mGy. Phantom organ dose for lung, heart, stomach, liver, kidney and brain were 11.07mGy, 5.87mGy, 1.42mGy, 2.11mGy, 6.76mGy and 0.001mGy respectively, and effective dose was 4mSv. For regular mode CTA, PSD was 74.5mGy, and CTD vol was 37.9mGy. Phantom organ dose for lung, heart, stomach, liver, kidney and brain were 58mGy, 64.2mGy, 6.6mGy, 9.9mGy, 2.7mGy, 0.072mGy respectively, and effective dose was 16mSv. For ECG modulation mode, PSD was 50.9mGy, and CTD vol was 26.3mGy. Conclusion: According to measured PSD value, deterministic radiation risk for regular mode CTA was little higher than DSA. However for stochastic radiation risk which can be indicated by organ dose and effective dose, regular mode CTA was much higher than DSA. Comparing with regular mode, ECG modulation mode can effectively reduce both stochastic and deterministic radiation risk. (author)

Innovative Development and Forecast of BeiDou System

Directory of Open Access Journals (Sweden)

TAN Shusen

2017-10-01

Full Text Available Due to the strong demand for satellite applications and rapid development of new space technology,the cross-integration of space-based radio systems has become a trend.BeiDou system started from two satellites to build China's first generation satellite navigation and positioning system with the features of fast location reporting(RDSSand short message communication(MSSservice.Then BeiDou technology frame combined with RNSS continuous navigation and RDSS location report,was constructed in eight years,and the coverage in Asia-Pacific was completed.Through effective satellite radio frequency compatible design and international coordination,BeiDou system is the first radio satellite system which includes RNSS,RDSS,MSS three major services,approved by International Telecommunication Union(ITUin the world.This paper expounds the development process,technical frame,main features and prospect of BeiDou system with three major services and four key functions,in the concept of innovation and transcendence.

Positron emission tomography in urological cancer; Positronenemissionstomographie bei urologischen Tumoren

Energy Technology Data Exchange (ETDEWEB)

Wit, M. de [Universitaetskrankenhaus Eppendorf, Hamburg (Germany). Abt. Onkologie/Haematologie, Medizinische Klinik; Kotzerke, J. [Universitaetsklinikum Ulm (DE). Radiologie III (Nuklearmedizin)

2000-09-01

In staging cancer of the urinary bladder, the kidneys and the prostate and of testicular cancer there is a need for detecting tumor involvement of the lymph nodes to avoid surgical exploration. Positron emission tomography (PET) using fluorodeoxyglucose (FDG) can detect tumorous lymph nodes (sensitivity: 70%, specificity: 85%) which is helpful for several patients. In carcinoma of the prostate, other radiotracers than FDG (e.g. C-11-choline) might be more sensitive to detect tumorous lymph nodes. Up to now no diagnostical benefit of PET in germ cell tumors could be demonstrated in the published small series. In principle FDG-PET is useful in diagnosis of recurrence. In germ cell cancer FDG-PET seems to identify effectively persistent vital tumor tissue after chemotherapy. A multicenter study was initiated to demonstrate the potential of FDG-PET in a sufficient number of patients with germ cell tumor. (orig.) [German] Bei Harnblasen-, Nieren-, Prostata- und Hodenkarzinomen besteht aus klinischer Sicht ein Bedarf an verbessertem Lymphknoten-Staging, um die operative Evaluation zu vermeiden. Die Positronenemissionstomographie (PET) mit Fluordeoxyglukose (FDG) kann daher im Einzelfall bei Harnblasen- und Nierenkarzinomen hilfreich sein (bei Sensitivitaet um 70% und Spezifitaet um 85%). Beim Prostatakarzinom koennten sich andere Radiotracer (z.B. C-11-Cholin) bei der Detektion von tumoroesen Lymphknoten ueberlegen erweisen. Bei Keimzelltumoren konnte ein Nutzen der PET im primaeren Staging bei den bisher publizierten kleinen Studien nicht nachgewiesen werden. Fuer die Rezidivdiagnostik ist bei den genannten Tumoren aus grundsaetzlicher Ueberlegung der Einsatz von DFG-PET sinnvoll. Die Erkennung von vitalem malignen Tumorgewebe nach Chemotherapie erscheint bei Keimzelltumoren mit FDG-PET weitgehend sicher zu gelingen. Eine multizentrische Studie wurde begonnen, die hierueber Aufschluss geben wird. (orig.)

Tumor vascularity of experimentally induced VX2 carcinoma in the rabbit thigh: evaluation with enhanced power doppler sonography and DSA correlated with histopathologic findings

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Kim, Young Hoon; Han, Joon Koo; Chung, Jin Wook; Lee, Kyoung Ho; Kim, Se Hyung; Kim, Seog Joon; Choi, Byung Ihn; Chang, Kee Hyun [College of Medicine, Seoul National Univ., Seoul (Korea, Republic of)

2002-05-01

To describe findings of enhanced power Doppler sonography and DSA in experimentally induced VX2 carcinomas in rabbit thigh and to correlate the imaging findings with the histopathologic features. A total of 30 VX2 carcinomas were implanted in rabbit thigh, and after conventional and enhanced power Doppler sonography and DSA, histopathologic examination was performed. Enhanced power Doppler sonography and DSA, were used to determine the distribution pattern of tumor vascularity; to assess its grade and the percentage of a tumor area occupied by vessels, conventional and enhanced power Doppler sonography, as well as DSA, were used. The grade of necrosis and the development of fibrovascular stroma and capsule were histopathologically determined. The findings of power Doppler sonography were compared with those of DSA and the imaging features were correlated with the histopathologic features. At enhanced power Doppler sonography, the signal was either avascular (n=9), peripheral (n=15) or diffuse (n=6), while at DSA, the corresponding totals were eight, fourteen and eight. There was statistically significant corelation between enhanced power Doppler sonogrpahy and DSA, both in their depiction of the distribution of patterns of tumor vascularity and as regards their findings of grade and percentage of vascular area. As determined by both conventional and enhanced power Doppler sonogrpahy, and by DSA, grade of necrosis and the development of fibrovascular stroma and a capsule correlated with grade and the percentage of vascular area. Experimentally induced VX2 carcinomas in rabbit thigh demonstrated various patterns of tumor vascularity, and the findings of enhanced power Doppler sonography correlated with those of DSA. Tumor vascularity, as demonstrated by two imaging modalities, correlated closely with grade of necrosis and the development of fibrovascular stroma and a capsule, as revealed by histopathologic examination.

Tumor vascularity of experimentally induced VX2 carcinoma in the rabbit thigh: evaluation with enhanced power doppler sonography and DSA correlated with histopathologic findings

International Nuclear Information System (INIS)

Kim, Young Hoon; Han, Joon Koo; Chung, Jin Wook; Lee, Kyoung Ho; Kim, Se Hyung; Kim, Seog Joon; Choi, Byung Ihn; Chang, Kee Hyun

2002-01-01

To describe findings of enhanced power Doppler sonography and DSA in experimentally induced VX2 carcinomas in rabbit thigh and to correlate the imaging findings with the histopathologic features. A total of 30 VX2 carcinomas were implanted in rabbit thigh, and after conventional and enhanced power Doppler sonography and DSA, histopathologic examination was performed. Enhanced power Doppler sonography and DSA, were used to determine the distribution pattern of tumor vascularity; to assess its grade and the percentage of a tumor area occupied by vessels, conventional and enhanced power Doppler sonography, as well as DSA, were used. The grade of necrosis and the development of fibrovascular stroma and capsule were histopathologically determined. The findings of power Doppler sonography were compared with those of DSA and the imaging features were correlated with the histopathologic features. At enhanced power Doppler sonography, the signal was either avascular (n=9), peripheral (n=15) or diffuse (n=6), while at DSA, the corresponding totals were eight, fourteen and eight. There was statistically significant corelation between enhanced power Doppler sonogrpahy and DSA, both in their depiction of the distribution of patterns of tumor vascularity and as regards their findings of grade and percentage of vascular area. As determined by both conventional and enhanced power Doppler sonogrpahy, and by DSA, grade of necrosis and the development of fibrovascular stroma and a capsule correlated with grade and the percentage of vascular area. Experimentally induced VX2 carcinomas in rabbit thigh demonstrated various patterns of tumor vascularity, and the findings of enhanced power Doppler sonography correlated with those of DSA. Tumor vascularity, as demonstrated by two imaging modalities, correlated closely with grade of necrosis and the development of fibrovascular stroma and a capsule, as revealed by histopathologic examination

[Affine transformation-based automatic registration for peripheral digital subtraction angiography (DSA)].

Science.gov (United States)

Kong, Gang; Dai, Dao-Qing; Zou, Lu-Min

2008-07-01

In order to remove the artifacts of peripheral digital subtraction angiography (DSA), an affine transformation-based automatic image registration algorithm is introduced here. The whole process is described as follows: First, rectangle feature templates are constructed with their centers of the extracted Harris corners in the mask, and motion vectors of the central feature points are estimated using template matching technology with the similarity measure of maximum histogram energy. And then the optimal parameters of the affine transformation are calculated with the matrix singular value decomposition (SVD) method. Finally, bilinear intensity interpolation is taken to the mask according to the specific affine transformation. More than 30 peripheral DSA registrations are performed with the presented algorithm, and as the result, moving artifacts of the images are removed with sub-pixel precision, and the time consumption is less enough to satisfy the clinical requirements. Experimental results show the efficiency and robustness of the algorithm.

Intravenous spiral CT angiography for assessment before orthotopic liver transplantation: Comparison between tomography, MIP, 3-dimensional surface imaging and intraarterial DSA

International Nuclear Information System (INIS)

Hidajat, N.; Vogl, T.J.; Moeller, M.; Bechstein, W.O.; Felix, R.

1996-01-01

Purpose: To analyse the efficacy of intravenous spiral CT angiography (SCTA) for the evaluation before orthotopic liver transplantation (oLT) compared with DSA. Methods: Spiral CT was performed on 31 potential recipients of a liver graft in order to examine hepatic vessels, coeliac axis, splenic artery and superior mesenteric artery. The arterial vessels were reconstructed in 'Maximum Intensity Projection (MIP)' and 'Shaded Surface Display (SSD)'-technique. The axial images, MIP and SSD were compared in 25 patients with DSA with regard to the visualisation of the vascular anatomy, detectability of stenosis and vascular diameters. Results: The type of arterial liver supply could be determined via SCTA in all patients. Stenosis of the coeliac axis was seen in ten patients on the DSA, MIP and SSD and in eight patients on the axial images. Occlusion of the hepatic artery was clearly visualised in two patients on the DSA, axial images and MIP and in one patient on the SSD. There was no false positive diagnosis with SCTA. SSD was seen as the best technique to visualise the vessels without overshadowing. There were no significant differences between the diamters measured from the axial images, MIP and SSD images in transversal direction and the DSA images (p>0.05). Conclusion: SCTA is a greatly promising method for the imaging of vessels supplying the liver before oLT, and may convey more diagnostic information than DSA. (orig.) [de

WDS/DSA Certification - International collaboration for a trustworthy research data infrastructure

Science.gov (United States)

Mokrane, Mustapha; Hugo, Wim; Harrison, Sandy

2016-04-01

, German Institute for Standardization (DIN) standard 31644, Trustworthy Repositories Audit and Certification (TRAC) criteria and the International Organization for Standardization (ISO) standard 16363. In addition, the Data Seal of Approval (DSA) and WDS have set up core certification mechanisms for trusted digital repositories in 2009, which are increasingly recognized as de facto standards. While DSA emerged in Europe in the Humanities and Social Sciences, WDS started as an international initiative with historical roots in the Earth and Space Sciences. Their catalogues of requirements and review procedures are based on the same principles of openness, transparency. A unique feature of the DSA and WDS certification is that it strikes a balance between simplicity, robustness and the effort required to complete. A successful international cross-project collaboration was initiated between WDS and DSA under the umbrella of the Research Data Alliance (RDA), an international initiative started in 2013 to promote data interoperability which provided a useful and neutral forum. A joint working group was established in early 2014 to reconcile and simplify the array of certification options and improve and stimulate core certification for scientific data services. The outputs of this collaboration are a Catalogue of Common Requirements (https://goo.gl/LJZqDo) and a Catalogue of Common Procedures (https://goo.gl/vNR0q1) which will be implemented jointly by WDS and DSA.

Initial assessment of the COMPASS/BeiDou-3: new-generation navigation signals

Science.gov (United States)

Zhang, Xiaohong; Wu, Mingkui; Liu, Wanke; Li, Xingxing; Yu, Shun; Lu, Cuixian; Wickert, Jens

2017-10-01

The successful launch of five new-generation experimental satellites of the China's BeiDou Navigation Satellite System, namely BeiDou I1-S, I2-S, M1-S, M2-S, and M3-S, marks a significant step in expanding BeiDou into a navigation system with global coverage. In addition to B1I (1561.098 MHz) and B3I (1269.520 MHz) signals, the new-generation BeiDou-3 experimental satellites are also capable of transmitting several new navigation signals in space, namely B1C at 1575.42 MHz, B2a at 1176.45 MHz, and B2b at 1207.14 MHz. For the first time, we present an initial characterization and performance assessment for these new-generation BeiDou-3 satellites and their signals. The L1/L2/L5 signals from GPS Block IIF satellites, E1/E5a/E5b signals from Galileo satellites, and B1I/B2I/B3I signals from BeiDou-2 satellites are also evaluated for comparison. The characteristics of the B1C, B1I, B2a, B2b, and B3I signals are evaluated in terms of observed carrier-to-noise density ratio, pseudorange multipath and noise, triple-frequency carrier-phase ionosphere-free and geometry-free combination, and double-differenced carrier-phase and code residuals. The results demonstrate that the observational quality of the new-generation BeiDou-3 signals is comparable to that of GPS L1/L2/L5 and Galileo E1/E5a/E5b signals. However, the analysis of code multipath shows that the elevation-dependent code biases, which have been previously identified to exist in the code observations of the BeiDou-2 satellites, seem to be not obvious for all the available signals of the new-generation BeiDou-3 satellites. This will significantly benefit precise applications that resolve wide-lane ambiguity based on Hatch-Melbourne-Wübbena linear combinations and other applications such as single-frequency precise point positioning (PPP) based on the ionosphere-free code-carrier combinations. Furthermore, with regard to the triple-frequency carrier-phase ionosphere-free and geometry-free combination, it is found

Wirksamkeit der Hypnose auf Schmerzen bei Erwachsenen: systematische Literaturreview

OpenAIRE

Pfaffen, Céline; Z`Brun-Schnyder, Silvia

2018-01-01

Das Ziel dieser systematischen Literaturreview ist es, die Wirksamkeit der Hypnose auf Schmerzen bei Erwachsenen zu überprüfen. Daraus ergibt sich folgende Forschungsfrage: "Wie wird die Wirksamkeit der Hypnose auf Schmerzen bei Erwachsenen in der wissenschaftlichen Literatur beschrieben?"

Digital subtraction angiography (DSA) for acute pulmonary emboli

International Nuclear Information System (INIS)

Witte, H.; Grabbe, E.; Buecheler, E.

1983-01-01

The results of 49 DSAs (in 29 patients) are presented; these were performed for the diagnosis or follow-up of pulmonary emboli. The direct or indirect signs of pulmonary emboli, known to occur during conventional pulmonary angiography, were used as diagnostic criteria. In 47 examinations it was possible to make or to exclude the diagnosis unequivocally. The advantages of DSA make it desirable to use this method as the first form of examination in the diagnosis of acute, but not immediately life-threatening, pulmonary emboli. (orig.) [de

Carotid DSA based CFD simulation in assessing the patient with asymptomatic carotid stenosis: a preliminary study.

Science.gov (United States)

Zhang, Dong; Xu, Pengcheng; Qiao, Hongyu; Liu, Xin; Luo, Liangping; Huang, Wenhua; Zhang, Heye; Shi, Changzheng

2018-03-12

Cerebrovascular events are frequently associated with hemodynamic disturbance caused by internal carotid artery (ICA) stenosis. It is challenging to determine the ischemia-related carotid stenosis during the intervention only using digital subtracted angiography (DSA). Inspired by the performance of well-established FFRct technique in hemodynamic assessment of significant coronary stenosis, we introduced a pressure-based carotid arterial functional assessment (CAFA) index generated from computational fluid dynamic (CFD) simulation in DSA data, and investigated its feasibility in the assessment of hemodynamic disturbance preliminarily using pressure-wired measurement and arterial spin labeling (ASL) MRI as references. The cerebral multi-delay multi-parametric ASL-MRI and carotid DSA including trans-stenotic pressure-wired measurement were implemented on a 65-year-old man with asymptomatic unilateral (left) ICA stenosis. A CFD simulation using simplified boundary condition was performed in DSA data to calculate the CAFA index. The cerebral blood flow (CBF) and arterial transit time (ATT) of ICA territories were acquired. CFD simulation showed good correlation (r = 0.839, P = 0.001) with slight systematic overestimation (mean difference - 0.007, standard deviation 0.017) compared with pressure-wired measurement. No significant difference was observed between them (P = 0.09). Though the narrowing degree of in the involved ICA was about 70%, the simulated and measured CAFA (0.942/0.937) revealed a functionally nonsignificant stenosis which was also verified by a compensatory final CBF (fronto-temporal/fronto-parietal region: 51.58/45.62 ml/100 g/min) and slightly prolonged ATT (1.23/1.4 s) in the involved territories, together with a normal left-right percentage difference (2.1-8.85%). The DSA based CFD simulation showed good consistence with invasive approach and could be used as a cost-saving and efficient way to study the relationship between

DSA analysis of the normal and variant hepatic arterial anatomy

International Nuclear Information System (INIS)

Lv Penghua; Wang Jie; Shi Haibing; Feng Yaoliang; Chen Huizhu; Chen Yuqin

2005-01-01

Objective: To observe and analyze the normal and variant hepatic arterial anatomy by DSA. Methods: One thousand and two hundreds patients with routine celiac and/or selective hepatic arteriography from November 1994 to March 2003 were retrospectively analyzed, some of them were further simultaneously undergone superior mesenteric arteriography, left gastric arteriography or inferior phrenic arteriography etc. Results: 873 (72.8%) patients had the standard hepatic arterial anatomy. 156(13.0%) patients had variant left hepatic arteries (LHAs), 120(10.0%) with variant right hepatic arteries (RHAs) and 21 (1.8%) of a variant anatomy involving both LHA and RHA. The common hepatic artery (CHA) of 1170 (97.5%) patients originated from the celiac artery. 92.0% proper hepatic artery (PHA) was the direct extension of CHA. The RHA was mainly (89.8%) derived from the PHA. There was some variation of the middle hepatic artery (MHA) with more than 62.2% arising from the LHA. The LHA was derived from the PHA (44.6%) or the RHA(30.2%) or other arteries (25.2%). Conclusions: The knowledge of normal and variant anatomy of hepatic vasculature by DSA may be very helpful for intervention therapy and hepatosurgery. (authors)

Entwicklungstrends bei landwirtschaftlichen Applikationen - ein Zwischenfazit

Directory of Open Access Journals (Sweden)

Christa Hoffmann

2014-10-01

Full Text Available Globalisierung, volatile Märkte und der vermehrte Rückzug der Agrarpolitik aus der Marktregulierung sorgen dafür, dass die Entscheidungsfindungsprozesse auf landwirtschaftlichen Betrieben an Komplexität zunehmen. Applikationen bieten durch ihre Mobilität und individuellen Ausgestaltungsmöglichkeiten Optionen, um den Landwirt bei seiner täglichen Arbeit zu unterstützen. In diesem Kontext nimmt diese Arbeit eine Bestandsaufnahme und Kategorisierung nativer Applikationen mit landwirtschaftlichem Bezug vor. Die Ergebnisse zeigen unter anderem einen Angebotsschwerpunkt im Produktionszweig Pflanzenbau und bei den Funktionen bestimmte häufig auftretende bedarfsbedingte Kombinationen (z. B. Planung und Analyse.

Knochenstoffwechsel bei malignen Erkrankungen

Directory of Open Access Journals (Sweden)

Keck A-V

2003-01-01

Full Text Available Bei malignen Erkrankungen, wie dem Mammakarzinom, dem Prostatakarzinom, dem Bronchialkarzinom oder dem multiplen Myelom ist der Knochen eines der am häufigsten von Metastasen betroffenen Organe. Das klinische Beschwerdebild ist durch das Auftreten pathologischer Frakturen, Schmerzen und Hyperkalzämien gekennzeichnet. Eine erhöhte Knochenresorptionsrate und Verlust an Knochenmasse im Sinne von osteoporoseartigen Veränderungen bedingt durch eine inadäquat überschießende Osteoklastendifferenzierung und -aktivierung sind ursächlich dafür verantwortlich. Durch jüngst publizierte Ergebnisse diverser Studien und Untersuchungen konnten die genauen Mechanismen der Rekrutierung und Aktivierung von Osteoklasten weiter aufgeklärt werden. Receptor activator of nuclear factor-kappa-B ligand (RANKL, ein Mitglied der Tumor necrosis factor (TNF Superfamilie konnte als entscheidender Faktor in der Osteoklastengenese identifiziert werden. Die Interaktion von RANKL mit seinem Rezeptor RANK (receptor activator of nuclear factor-kappa-B induziert die Entwicklung der osteoklastären Reihe aus dem hämatopoetischen Kompartment und fördert weiters die Differenzierung zu Osteoklastenvorstufen und die Aktivierung reifer Osteoklasten, ebenso wird eine verzögert einsetzende Apoptose bewirkt. Neben RANK und RANKL ist Osteoprotegerin (OPG als dritte Komponente in der Regulation der Knochenresorption involviert. Als Mitglied der TNF-Superfamilie bindet OPG an RANKL und blockiert somit alle stimulierenden Effekte von RANK auf die Osteoklastenentwicklung und neutralisiert so alle biologischen Effekte von RANKL. Diverse Hormone und Zytokine üben durch die Modifikation der Ratio von RANKL zu OPG einen regulatorischen Effekt auf die Knochenresorption aus. Diese ist bei osteolytischen Knochenmetastasen, beim multiplen Myelom und bei der malignen Hyperkalzämie erhöht. Das Gleichgewicht knochenaufbauender wie -abbauender Mechanismen scheint somit durch die Ratio von

Experiences from the LNPP-P and DSA review. Lessons learned from RBMK safety studies

International Nuclear Information System (INIS)

Mankamo, T.; Marttila, J.; Reponen, H.

2000-09-01

RBMK is the Russian acronym for 'Channelized Large Power Reactor'. The Soviet-designed RBMK plants deviate substantially from typical Western BWR or PWR plants. The safety of the RBMK plants has raised severe concerns since the major accident at Chernobyl Unit 4 in 1986. In addition, a fire destroyed the turbine hall of Chernobyl Unit 2 in 1991 resulting in a near-accident: the reactor cooling could only be maintained through improvised measures. Another well-known fire event is the control cable room fire at Ignalina Unit 2 in 1989, which led to a partial loss of the main control room functions. After the collapse of Soviet Union several multilateral safety programs were started to evaluate and improve the safety of the RBMK plants. A Probabilistic and Deterministic Safety Assessment (P and DSA) of the Leningrad Nuclear Power Plant (LNPP) Unit 2 was started in 1996. Phase 2 of the project was completed in January 1999. A Peer Review was performed by Russian and Western experts. This report describes the insights from the RBMK risk studies, especially from the LNPP P and DSA with emphasis on the deeper understanding of the risk-important design factors and identification of possible ways to increase safety. LNPP P and DSA has meant a significant progress in this respect. Despite of its certain limitations P and DSA Phase 2 could point out short-term measures, which substantially reduced the risk of identified weaknesses, mostly related to the reliability of the emergency feedwater function and its support systems. The findings of LNPP P and DSA and the review recommendations emphasise the extensions needed to the analysis scope. The spreading and other influences of fires and floods between connected spaces should be analysed because of incomplete separation and protection in these regards in the 16st generation RBMK plants. High priority should be given to the analysis of external hazards, which were found important at the Loviisa NPP on the Northern side of the

Experiences from the LNPP-P and DSA review. Lessons learned from RBMK safety studies

Energy Technology Data Exchange (ETDEWEB)

Mankamo, T. [Avaplan Oy (Finland); Marttila, J.; Reponen, H. [Radiation and Nuclear Safety Authority, Helsinki (Finland)

2000-09-01

RBMK is the Russian acronym for 'Channelized Large Power Reactor'. The Soviet-designed RBMK plants deviate substantially from typical Western BWR or PWR plants. The safety of the RBMK plants has raised severe concerns since the major accident at Chernobyl Unit 4 in 1986. In addition, a fire destroyed the turbine hall of Chernobyl Unit 2 in 1991 resulting in a near-accident: the reactor cooling could only be maintained through improvised measures. Another well-known fire event is the control cable room fire at Ignalina Unit 2 in 1989, which led to a partial loss of the main control room functions. After the collapse of Soviet Union several multilateral safety programs were started to evaluate and improve the safety of the RBMK plants. A Probabilistic and Deterministic Safety Assessment (P and DSA) of the Leningrad Nuclear Power Plant (LNPP) Unit 2 was started in 1996. Phase 2 of the project was completed in January 1999. A Peer Review was performed by Russian and Western experts. This report describes the insights from the RBMK risk studies, especially from the LNPP P and DSA with emphasis on the deeper understanding of the risk-important design factors and identification of possible ways to increase safety. LNPP P and DSA has meant a significant progress in this respect. Despite of its certain limitations P and DSA Phase 2 could point out short-term measures, which substantially reduced the risk of identified weaknesses, mostly related to the reliability of the emergency feedwater function and its support systems. The findings of LNPP P and DSA and the review recommendations emphasise the extensions needed to the analysis scope. The spreading and other influences of fires and floods between connected spaces should be analysed because of incomplete separation and protection in these regards in the 16st generation RBMK plants. High priority should be given to the analysis of external hazards, which were found important at the Loviisa NPP on the Northern

KRITIK SOSIAL DALAM KOMIK STRIP PAK BEI

Directory of Open Access Journals (Sweden)

Yudhi Novriansyah

2016-08-01

Full Text Available This research aimed to do interpret the marking which flange social criticism and know laboring ideology in story of Comic Strip Pak Bei. Research based on theory of structural semiotic according to Ferdinand De Saussure. Using analysis of Syntagmatic as first level of meaning to the text network and also picture, and analysis of Paradigmatic as second level of meaning or implicit meaning (connota-tion, myth, ideology Analysis done to six Comic choice edition of Strip Pak Bei period of November 2004 - Februari 2005 which tend to flange social criticism. At band of syntagmatic, result of research indicate that story theme lifted from social problems that happened in major society. The fact clear progressively when connected by Intertextual with information and texts which have preexisted. At band of Paradigmatic, social criticism tend to emerge dimly, is not transparent. Because of Comic Strip Pak Bei expand in the middle of Java cultural domination that developing myth of criticize as action menacing compatibility and orderliness of society. Story of Comic Strip Pak Bei also confirm dominant ideology in Java society culture, namely ideology of Patriarkhi and Feudalism which still go into effect until now. This prove ideology idea according to Louis Althusser which not again opposition between class, but have been owned and practiced by all social class.

DSA study of the effect of vasopressin on the small-bowel circulation before and after embolization

International Nuclear Information System (INIS)

Li Xueqin; Wang Qiaoxi; Guo Yuxin; Yang Xinhong; Hu Hongyao

2001-01-01

Objective: To study the effect of vasopressin (VS) on the small-bowel circulation and the safety of embolotherapy for the small intestinal hemorrhage by DSA. Methods: Ten dogs were divided into three groups. Vasa recta were ligated 30 min after VS infusion ended in group A (n = 4), and 2h after VS infusion ended in group B (n = 4), they were ligated without VS infusion in control group (n = 2). DSA were performed before and after VS infusion, before and after the ligation. The tested parts of intestine were resected to make the pathologic examination a week late. Results: All branches of mesenteric arteries contracted and the contrast developed light in the intestinal wall after VS infusion. Branches contraction recovered but the contrast developed still slight in the intestinal wall about 30 min after infusion ended. All manifestation of DSA recovered to normal 2h after infusion ended. In all groups, the blood vessel net can be seen but is fewer and scattered in the area of ligation. The collocate presented soon after the ligation. The pathologic examination proved that there was only mind mucosal ischemia in all groups. Conclusion: The repressive effect of VS to the circulation of intestine weakened and then disappeared rapidly after the infusion ended. VS infusion had no significant effect on the safety of embolotherapy for small intestinal bleeding when the infusion has been finished for more than 2hr. DSA can demonstrated the circulation state of the intestine before and after embolization

Digital substraction angiography (DSA) in a universal radiodiagnostic room with a novel multi-pulse high-frequency generator

International Nuclear Information System (INIS)

Ellegast, H.H.; Kloss, R.; Mayr, H.; Ammann, E.; Kuehnel, W.; Siemens A.G., Erlangen

1985-01-01

Application of digital subtraction angiography in a universal radiodiagnostic room can be implemented rapidly and reliably. The number of examinations could be increased without negative effects to conventional operations in this room. At optimum radiation hygiene and high-degree operational safety, the multipulse high-frequency generator with its DSA parameter automatic system guarantees a reproducibly good image quality equalling that of a special DSA facility. In this way, the examination room constitutes an economic solution for small-sized hospitals without any special angiography room, too. (orig.) [de

Krafttraining bei älteren "frail" Personen

Directory of Open Access Journals (Sweden)

Kapan A

2013-01-01

Full Text Available Aufgrund der demographischen Entwicklung in den westlichen Industrieländern kann bei einem Ausbleiben adäquater Präventionsmaßnahmen davon ausgegangen werden, dass in Österreich im Jahr 2050 356.000 gebrechliche („frail“ und 1,5 Millionen Personen mit Vorstufen erwartet werden können. Im Alter von 50–70 Jahren kann auch bei gesunder Ernährung und körperlicher Aktivität die Muskelkraft um bis zu 30 % nachlassen. Für den Erhalt der Mobilität und um dem Muskelabbau entgegenzuwirken nimmt das körperliche Training, vor allem das Krafttraining, einen wichtigen Stellenwert ein.

Intravenous digital subtraction angiography of the lower limbs combined with field movement (2-field DSA)

International Nuclear Information System (INIS)

Fritschy, P.; Terrier, F.

1988-01-01

We evaluated a bolus-chase technique designed to reduce the volume of contrast material and to shorten examination time during intravenous digital subtraction angiography (IV-DSA) of the lower limbs. With this technique, after a single injection of contrast material, two contiguous fields can be sequentially imaged (two-field DAS) using a step translated X-ray tube. 67 patients with peripheral vascular disease were studied. All examinations provided diagnostic information, so that in no instance additional intra-arterial injections were required. With the two-field DSA only 3.49 injections were needed in the average for five fields examined in each patient, resulting in a 30% reduction of contrast agent used. (orig.) [de

The application of DSA bolus chase technology in diagnosing the vascular disorders of lower extremities due to diabetes mellitus

International Nuclear Information System (INIS)

Ren Chongyang; Di Zhenhai; Mao Xuequn; Zou Rong; Zhang Jian; Wang Meirong; Li Quan

2010-01-01

Objective: To retrospectively evaluate the digital subtraction angiography (DSA) bolus chase technology in diagnosing the vascular disorders of lower extremities due to diabetes mellitus. Methods: From January 2004 to March 2010, DSA was performed in forty-five diabetes patients with suspicious vascular diseases of lower extremities. Among them, 24 cases (31 lower limbs)were examined with DSA bolus chase technology and the remaining 21 cases (21 lower limbs)were examined with traditional segmentational technique. The contrast dosage used in angiography, the total exposure time, the examination time and the imaging value for making diagnosis were analyzed and compared between two techniques. Results: For DSA bolus chase technology group, the contrast dosage used in angiography, the total exposure time and the examination time were 25.26 ml, 13.23 s and 37.26 min, respectively,with an average exposure of 101.65 pictures. For traditional segmentational technique group, the contrast dosage used in angiography, the total exposure time and the examination time were 130.00 ml, 52.38 s and 50.48 min, respectively, with an average exposure of 118.33 pictures. The percentage of high quality images in bolus chase technology group and in traditional segmentational technique group were 90.3% and 90.5%, respectively. All the images could meet the requirements for making a reliable diagnosis. Conclusion: Digital subtraction angiography by using bolus-chase technology can well demonstrate the vascular pathology of lower extremities caused by diabetes mellitus, obtain sufficient imaging information necessary for making a reliable diagnosis. DSA bolus chase technology is superior to traditional segmentational technique in shortening procedure time, reducing contrast medium dosage and decreasing radiation dose. (authors)

Osteoporose bei Mb. Bechterew - neue Ansätze

Directory of Open Access Journals (Sweden)

Obermayer-Pietsch B

1999-01-01

Full Text Available Eine axiale Osteoporose und daraus resultierende vertebrale Kompressionsfrakturen sind häufige Symptome eines Mb. Bechterew (MbB, Spondylarthritis ankylosans. Als ein möglicher genetischer Faktor der Osteoporose wurde eine Assoziation der Knochendichte (BMD mit BsmI- und FokI-Polymorphismen im Vitamin D-Rezeptor-(VDR-Gen publiziert. In der vorliegenden Studie wurden die Beziehungen zwischen diesen Polymorphismen, Knochenstoffwechsel, BMD und Aktivitätsindizes bei Patienten mit MbB untersucht. Bei 47 MbB-Patienten wurden Aktivitätsindizes und morphologische Parameter sowie BMD-Messungen (Dual-Röntgen-Absorptiometrie an Wirbelsäule und Schenkelhals im Vergleich zu 52 gesunden, altersgleichen Personen erhoben. Die Laborbestimmungen umfaßten biochemische Aktivitätsparameter, HLA-Typisierung sowie Knochenan- und -abbaumarker. Aus peripheren Leukozyten wurde genomische DNA präpariert und mittels Polymerase-Kettenreaktion (PCR und anschließender FokI- und BsmI-Restriktion der VDR-Genotyp nach vorhandenen bzw. fehlenden Schnittstellen (f/b bzw. F/B bestimmt. Bei MbB-Patienten fand sich eine Osteoporose deutlich häufiger als in der Kontrollgruppe. Eine Zuordnung von Aktivitätsindizes, BMD und Knochenstoffwechselparametern zu den Genotypen zeigte bei männlichen MbB-Patienten sowohl eine Assoziation der WS-Knochendichte als auch der Entzündungsmarker mit FokI-, nicht jedoch mit BsmI-Genotypen des VDR. Die pathophysiologischen Mechanismen dieser Assoziation, insbesondere mit der entzündlichen Aktivität des Mb. Bechterew, sind noch ungeklärt. Eine frühzeitige Erfassung des Osteoporoserisikos bei MbB-Patienten mittels molekularbiologischer Tests könnte eine rechtzeitige Prophylaxe und Therapie dieser Komplikation ermöglichen.

Two-phase summation imaging using transvenous DSA in subclavian steal syndrome

International Nuclear Information System (INIS)

Arlart, I.P.

1984-01-01

A simple method is reported to obtain a two-phase summation image in subclavian steal syndrome using digital subtraction angiography (DSA) via selection of a mask during the early arterial phase and the contrast image during delayed retrograde filling of the ipsilateral vertebral artery and the postocclusive subclavian artery. The summation image results by employing replay of the stored image information. (orig.) [de

Imaging of left ventricular wall motion via venous DSA

International Nuclear Information System (INIS)

Witte, G.; Roediger, W.; Buecheler, E.; Hamburg Univ.

1986-01-01

Until now, angiographical and nuclear medicine examination techniques for imaging left ventricular wall motion have been presenting with difficulties endemic to the methods themselves. For the first time in cardiological diagnostics, digital subtraction angiography (DSA) makes it possible to perform a fairly non-invasive examination with good spatial and temporal resolution. Functional analytic evaluation, however, still demands time-consuming, complicated post-processing. In this article we introduce a method that uses an additive window technique for the immediate generation of wall motion images. (orig.) [de

UMA PROSPOSTA DEDUTIVISTA PARA PRINCÍPIOS CONTÁBEIS

Directory of Open Access Journals (Sweden)

Paulo Schmidt

2009-09-01

Full Text Available A proposta deste estudo a apresentar um breve relato sobre a evolução do pensamento cientifico ocorrida na física com a substituição dos princípios contábeis e filosófico, desde a Antiguidade grega ate os dias de hoje, como forma de fundamentar o posicionamento contrario ao raciocínio indutivo para o estabelecimento de uma estrutura conceitual para a contabilidade e para o desenvolvimento dos princípios contábeis. Apos essa incursão pelo campo filosófico, será aduzido um dos trabalhos de D. R. Scott, ex-professor da Universidade de Michigan, que já na década de 1930 defendia o processo de raciocínio dedutivo e a necessidade de coerência e unidade para o estabelecimento dos princípios contábeis. Este estudo justifica-se, principalmente, porque ainda existem pesquisadores da área contábil que defendem o método indutivo com único procedimento cientifico capaz de levar a certeza, Como defendia Descartes. Alem disso, mesmo apos a revolução cientifica princípios teóricos de Newton, pelos princípios da teoria da relatividade de Einstein, alguns pesquisadores defendem a imutabilidade dos princípios contábeis, como sendo verdades indubitáveis, não aceitando o permanente desenvolvimento da teoria contábil e sua continua adaptabilidade a nova realidade ambiental. A contabilidade, assim como toda disciplina do conhecimento humano que postula um patamar cientifico, deve estruturar-se com base em um conjunto de princípios racionalmente dispostos. Diante desse panorama, faz-se mister inquirir se os princípios contábeis podem ser oniscientes e impassíveis as mudanças do mundo?

Pneumonia in immunosuppressed patients; Pneumonien bei immunsupprimierten Patienten

Energy Technology Data Exchange (ETDEWEB)

Solyanik, O.; Gaass, T.; Hellbach, K. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer klinische Radiologie, Muenchen (Germany); Dinkel, J. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer klinische Radiologie, Muenchen (Germany); Comprehensive Pneumology Center Munich (CPC-M), Muenchen (Germany)

2017-01-15

Pulmonary infections are a common complication in immunosuppressed patients with a frequently fatal prognosis despite modern prophylactic therapy. An early and correct diagnosis is important for initiation of the appropriate therapy. Chest radiography is the preferred initial imaging examination but is not accurate enough for the detection of pulmonary infections in immunosuppressed patients. Pneumonia is caused by a broad spectrum of pathogens in immunocompromised patients. In addition to imaging, the clinical history and epidemiology also play an important role in the diagnostics. Using epidemiological and anamnestic information, computed tomography (CT) shows a significantly better sensitivity and specificity particularly for the diagnosis of atypical forms of pneumonia. Due to the exact imaging of the different infiltration patterns CT provides an increased sensitivity with respect to the etiological classification of pulmonary infections. This article reviews in particular the radiological findings of commonly occurring pulmonary infections in immunosuppressed patients. (orig.) [German] Pneumonien bei immunsupprimierten Patienten sind haeufige Komplikationen, die trotzt moderner Prophylaxe toedlich verlaufen koennen. Eine korrekte Diagnose ist daher von entscheidender Bedeutung, um die richtige Therapie einleiten zu koennen. Die Roentgenthoraxaufnahme ist selten spezifisch genug fuer die genaue Einordnung atypischer Pneumonien in Folge einer Immunsuppression. Pneumonien unter Immunsuppression werden durch ein sehr breites Erregerspektrum verursacht. Eine wichtige Rolle bei der Diagnosefindung spielen neben der Bildgebung auch die klinische Anamnese und Epidemiologie. Mithilfe der klinischen Anamnese und Epidemiologie bietet die Computertomographie (CT) bei immunsupprimierten Patienten zum einen eine erhoehte Sensitivitaet bei der Detektion insbesondere atypischer Pneumonien. Zum anderen weist die CT durch die exakte Abbildung unterschiedlicher Infiltratmuster

The dose-area product in DSA

International Nuclear Information System (INIS)

Gfirtner, H.

1995-01-01

In DSA, the dose-area product shows a very good correlation with the maximum incidence dose. It may therefore serve as a reliable basis for the assessment of radiation doses to patients. The dose-area product is also a useful tool for the detection pf peak shifts in the radiation curves for certain investigations. In view of the considerable scatter of the values for the dose-area product these must, however, be subjected to an additional statistical analysis. Provided that this rule is observed, the dose-area product will considerably gain in importance for the monitoring of radiation exposures of patients. A very noteworthy learning effect could be achieved, if it would be made mandatory for those statistical analyses to be carried out not only on an investigation-specific but also an investigator-specific basis. The latter is particularly true of teaching hospitals. (orig./VHE) [de

PET in cerebrovascular disease; PET bei zerebrovaskulaeren Erkrankungen

Energy Technology Data Exchange (ETDEWEB)

Herholz, K. [Neurologische Universitaetsklinik der Univ. Koeln (Germany)]|[Max-Planck-Institut fuer Neurologische Forschung, Koeln (Germany)

1997-03-01

Tissue viability is of particular interest in acute cerebral ischemia because it may be preserved if reperfusion can be achieved rapidly, e.g. by acute thrombolysis. Measurements of regional cerebral blood flow (CBF) and oxygen consumption by PET can assess tissue viability, and they have substantially increased our knowledge of th pathophysiology of ischemic stroke and the associated penumbra. Widerspread clinical application in acute stroke, however, is unlikely because of the large logistic and personnel resources required. In chronic cerebrovascular disease, measurement of regional CBF and glucose metabolism, which is usually coupled, provide detailed insights in disturbance of cortical function, e.g. due to deafferentiation, and contribute to differentiation of dementia types. Chronic misery perfusion, i.e. reduced perfusion that does not match the metabolic demand of the tissue, can be demonstrated by PET. It may be found in some patients with high-grade arterial stenoses. Less severe impairment of brain perfusion can be demonstrated by measurement of the cerebrovascular reserve capacity. The most frequent clinical situations can be assessed by less demanding procedures, e.g. by SPECT. In conclusion, PET has its role in cerebrovascular disease primarily within scientific studies, where high resolution and absolute quantitation of physiological variables are essential. (orig.). 65 refs. [Deutsch] Beim akuten ischaemischen Insult ist die Vitalitaet des Gewebes von besonderem Interesse, da sie durch rasche Reperfusion, z.B. durch Thrombolyse, erhalten bleiben kann. Messungen der zerebralen Durchblutung und des Sauerstoffumsatzes mittels PET geben darueber wesentliche Aufschluesse, und sie sind wichtig fuer das Verstaendnis der Pathophysiologie ischaemischer Infarkte und der Penumbra mit kritischer Perfusion beim Menschen. Ihre breitere Anwendung in der klinischen Patientenversorgung kommt allerdings wegen des hohen Aufwandes derzeit kaum in Betracht. Bei

Development and Evaluation of the Biogenic Emissions Inventory System (BEIS) Model v3.6

Science.gov (United States)

We have developed new canopy emission algorithms and land use data for BEIS v3.6. Simulations with BEIS v3.4 and BEIS v3.6 in CMAQ v5.0.2 are compared these changes to the Model of Emissions of Gases and Aerosols from Nature (MEGAN) and evaluated the simulations against observati...

A comparative study of pulmonary hypoperfusion secondary to cancerous invasion of central pulmonary artery in lung cancer with CT and DSA

International Nuclear Information System (INIS)

Guo Dajing; Miao Jingtao; Lu Wusheng; Bai Hongli

2003-01-01

Objective: To study CT features of pulmonary hypoperfusion in lung cancer with cancerous invasion of central pulmonary artery (CICPA) and the diagnostic value of CT. Methods: The pre-operative pulmonary DSA and contrast-enhanced spiral CT (including HRCT) findings in 20 cases of lung cancer with CICPA were carried out prospectively and comparatively. On DSA and CT, the distribution and quantitative variation of subpleural terminal pulmonary arterioles (pulmonary vessel signs), the filling degree of lung capillary, the post-contrast density changes of lung parenchyma, and the fluctuations of the time-density curve (pulmonary parenchymal signs) were blindly observed. The CT and DSA findings and their consistence were analyzed statistically. The diagnostic values of CT in secondary pulmonary hypoperfusion in lung cancer with CICPA were evaluated. Results: There were 30 lobar arteries with cancerous invasion among the 20 cases and 90% (27/30) of them presented pulmonary hypoperfusion on DSA. For diagnosing pulmonary hypoperfusion, CT had a sensitivity of 78%(21/27), a specificity of 100% (3/3), and an accuracy of 80%(24/30). There were no statistical correlation between pulmonary hypoperfusion and the degree of central pulmonary artery (CPA) stenosis (r s =0.40, P=0.073). Pulmonary vessel signs on CT had a good consistence with that on DSA (Kappa=0.69, P<0.001), while that of pulmonary parenchymal signs was lower (Kappa=0.37, P=0.011). Conclusion: Pulmonary hypoperfusion is one of the common findings in lung cancer with CICPA. CT is of great value in qualitative diagnosis on it, while for quantitative diagnosis, its value is limited to a certain degree

An intercomparison of biogenic emissions estimates from BEIS2 and BIOME: Reconciling the differences

Energy Technology Data Exchange (ETDEWEB)

Wilkinson, J.G. [Alpine Geophysics, Pittsburgh, PA (United States); Emigh, R.A. [Alpine Geophysics, Boulder, CO (United States); Pierce, T.E. [Atmospheric Characterization and Modeling Division/NOAA, Research Triangle Park, NC (United States)

1996-12-31

Biogenic emissions play a critical role in urban and regional air quality. For instance, biogenic emissions contribute upwards of 76% of the daily hydrocarbon emissions in the Atlanta, Georgia airshed. The Biogenic Emissions Inventory System-Version 2.0 (BEIS2) and the Biogenic Model for Emissions (BIOME) are two models that compute biogenic emissions estimates. BEIS2 is a FORTRAN-based system, and BIOME is an ARC/INFO{reg_sign} - and SAS{reg_sign}-based system. Although the technical formulations of the models are similar, the models produce different biogenic emissions estimates for what appear to be essentially the same inputs. The goals of our study are the following: (1) Determine why BIOME and BEIS2 produce different emissions estimates; (2) Attempt to understand the impacts that the differences have on the emissions estimates; (3) Reconcile the differences where possible; and (4) Present a framework for the use of BEIS2 and BIOME. In this study, we used the Coastal Oxidant Assessment for Southeast Texas (COAST) biogenics data which were supplied to us courtesy of the Texas Natural Resource Conservation Commission (TNRCC), and we extracted the BEIS2 data for the same domain. We compared the emissions estimates of the two models using their respective data sets BIOME Using TNRCC data and BEIS2 using BEIS2 data.

Zeitlicher Verlauf der avaskulären Nekrose des Hüftkopfes bei Patienten mit Pemphigus vulgaris.

Science.gov (United States)

Balighi, Kamran; Daneshpazhooh, Maryam; Aghazadeh, Nessa; Saeidi, Vahide; Shahpouri, Farzam; Hejazi, Pardis; Chams-Davatchi, Cheyda

2016-10-01

Pemphigus vulgaris (PV) wird in der Regel mit systemischen Corticosteroiden und Immunsuppressiva behandelt. Avaskuläre Nekrose (AVN) des Hüftkopfes ist eine gut bekannte schwerere Komplikation einer Corticosteroid-Therapie. Die Charakteristika dieser schweren Komplikation bei PV sind nach wie vor unbekannt. Nicht kontrollierte, retrospektive Untersuchung aller PV-bedingten AVN-Fälle, die in einer iranischen Klinik für bullöse Autoimmunerkrankungen zwischen 1985 und 2013 diagnostiziert wurden. Anhand der Krankenakten von 2321 untersuchten PV-Patienten wurden 45 Fälle (1,93 %) von femoraler AVN identifiziert. Dreißig davon waren Männer. Das mittlere Alter bei der Diagnose der AVN betrug 47,4 ± 14,2 Jahre. Der mittlere Zeitraum zwischen der Diagnose des PV und dem Einsetzen der AVN lag bei 25,3 ± 18,3 Monaten. Mit Ausnahme von acht Fällen (17,8 %) setzte die AVN bei der Mehrheit der Patienten innerhalb von drei Jahren nach Diagnose des PV ein. Die mittlere kumulative Dosis von Prednisolon bei Patienten mit AVN betrug 13.115,8 ± 7041,1 mg. Zwischen der Prednisolon-Gesamtdosis und dem Zeitraum bis zum Einsetzen der AVN bestand eine starke Korrelation (p = 0,001). Bei Patienten mit Alendronateinnahme in der Vorgeschichte war dieser Zeitraum signifikant kürzer (p = 0,01). Die AVN ist eine schwere Komplikation einer Corticosteroid-Behandlung bei Patienten mit PV. Sie wird bei 2 % der Patienten beobachtet und tritt vor allem in den ersten drei Behandlungsjahren auf. Bei Patienten, die höhere Dosen von Prednisolon erhalten, setzt die AVN tendenziell früher ein. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

DSA-guided embolization in establishing different canine spinal cord ischemia models and relevant diffusion-weighted imaging study

International Nuclear Information System (INIS)

Zhang Jingsong; Sun Lijun; Huan Yi; He Hongde; Zhang Xuexin; Zhao Haitao; Zhang Jing; Zhang Xijing

2006-01-01

Objective: To evaluate DSA-guided embolization in establishing different spinal cord ischemia models of canine and relevant diffusion-weighted imaging (DWI) application. Methods: Nine canines were randomly divided into three groups with different matching of lipiodol and diatrizoate meglumine which were injected into bilateral intercostal arteries at 9-11 level guided by DSA monitor. Then observe the changes of motor function and pathologic findings, especially perform routine MRI and DWI by a 1.5 T MR system. Results: Except one case, 8 embolization models were established successfully. Among three groups, slight-group got slight injury and muscle power was about 3-5 grade and range of injury was about two vertebra distance; medium-group presented obvious paraplegia and muscle power was 0-1 grade and range of injury was between 3-4 vertebra distance; severe-group showed greater severity and larger range of injury. All lesions presented high signals at routine MRI and DWI. Conclusion: Using different matching of lipiodol and diatrizoate meglumine can establish different spinal cord ischemia models of canine by DSA- guided embolization and DWI can be performed successfully by 1.5 T MR system, which may be a good method for advanced study of spinal cord ischemia. (authors)

UMA PROSPOSTA DEDUTIVISTA PARA PRINCÍPIOS CONTÁBEIS

OpenAIRE

Paulo Schmidt

2009-01-01

A proposta deste estudo a apresentar um breve relato sobre a evolução do pensamento cientifico ocorrida na física com a substituição dos princípios contábeis e filosófico, desde a Antiguidade grega ate os dias de hoje, como forma de fundamentar o posicionamento contrario ao raciocínio indutivo para o estabelecimento de uma estrutura conceitual para a contabilidade e para o desenvolvimento dos princípios contábeis. Apos essa incursão pelo campo filosófico, será aduzido um dos trabalhos d...

Vitex-agnus-castus-Extrakt (Ze 440 zur Symptombehandlung bei Frauen mit menstruellen Zyklusstörungen

Directory of Open Access Journals (Sweden)

Eltbogen R

2015-01-01

Full Text Available Ziel: Diese nichtinterventionelle Beobachtungsstudie (NIS wurde von Schweizer Gynäkologen und Allgemeinmedizinern im Rahmen der üblichen ärztlichen Grundversorgung durchgeführt. Das Ziel der NIS war es, die Wirksamkeit und Sicherheit von Vitex-agnus-castus-(VAC Extrakt (Ze 440: premens, Zeller Medical AG, Romanshorn, Schweiz bei Frauen, die unter menstruellen Zyklusstörungen wie Polymenorrhö, Oligomenorrhö oder Amenorrhö litten, zu untersuchen. Methode: Insgesamt 211 Patientinnen nahmen an dieser NIS teil. Symptome, die mit menstruellen Zyklusstörungen („menstrual cycle irregularities“ [MCIs] und der Menstruationsblutung in Verbindung stehen, wurden bei einer Erstuntersuchung („baseline visit“ [BV] und einer Kontrolluntersuchung („follow-up visit“ [FV] nach Behandlung mit VAC-Extrakt über einen Zeitraum von 3 aufeinanderfolgenden Menstruationszyklen beurteilt. Ergebnisse: Der Anteil der Patientinnen, bei denen eine Beschwerdefreiheit oder eine Besserung der MCIs (insgesamt und spezifischer Beschwerdebilder wie Polymenorrhö, Oligomenorrhö und Amenorrhö erzielt werden konnte, lag bei der FV bei 79–85 %. Bei Symptomen im Zusammenhang mit der Menstruationsblutung wie Dysmenorrhö, Zwischenblutungen, Hypermenorrhö, Menometrorrhagie, Ovulationsblutung, präoder postmenstrueller Blutung betrug der Anteil der Patientinnen, bei denen ein Rückgang oder eine Besserung festgestellt wurde, bei der FV zwischen 60 und 88 %. Von 53 Patientinnen, die bei der BV von einem unerfüllten Kinderwunsch berichteten, wurden 12 Frauen (23 % während der Behandlung mit VAC-Extrakt schwanger. Bei der FV waren 91 % der Ärzte und 92 % der Patientinnen mit den erzielten Behandlungsergebnissen „zufrieden“ oder „sehr zufrieden“ und 80 % der Patientinnen bestätigten, dass sie gerne mit der Behandlung mit VAC-Extrakt fortfahren wollen. Fazit: Diese Beobachtungsstudie im Bereich der ärztlichen Grundversorgung ergab, dass die Behandlung mit VAC

Evolution und Funktionsvariabilität von bunodonten Molaren bei Primaten

OpenAIRE

Menz, Ulrike Maria (Doktor)

2017-01-01

In der vorliegenden Arbeit werden funktionale Details der Okklusion während der Mastikation bei ausgewählten fossilen und rezenten Primaten quantitativ vergleichend untersucht. Dazu wurden die Okklusionsflächen von antagonistischen Molarenpaaren mit modernen virtuellen Verfahren eingescannt und anhand von 3D Kronenmodellen kartiert und funktional ausgewertet. Die in der Forschergruppe DFG FOR 771 entwickelte Software „Occlusal Fingerprint Analyser“ (OFA) kam erstmals bei einer großen Stichpro...

Carbon dioxide DSA: An alternative to nonionic contrast material

International Nuclear Information System (INIS)

Hawkins, I.F.; Siragusa, R.; Mietling, S.; Storm, B.; Hawkins, M.; Hirko, R.; Colella, J.

1987-01-01

Over the past 6 years the authors have used CO/sub 2/ with DSA as a contrast agent in over 400 cases for arteriography, venography, portography, and opacification of the biliary and urinary tree. The compressibility of the CO/sub 2/ made consistent delivery difficult. Two injectors were designed which reliably delivered the exact amount of the inexpensive CO/sub 2/ which is required. This improved vascular opacification, collateral filling, and tumor AV shunting without any complications or discomfort. Selective renal artery injections were performed in over 20 patients with renal failure without any increase in creatinine. The authors' experience with animals, patients, and the new injectors are illustrated

Follow-up of intracranial aneurysms treated by a WEB flow disrupter: a comparative study of DSA and contrast-enhanced MR angiography.

Science.gov (United States)

Mine, Benjamin; Tancredi, Illario; Aljishi, Ali; Alghamdi, Faisal; Beltran, Margarita; Herchuelz, Maxime; Lubicz, Boris

2016-06-01

To compare contrast-enhanced MR angiography (CE-MRA) and DSA for the follow-up of intracranial aneurysms (IAs) treated with the Woven EndoBridge embolization system DL (WEB DL; Sequent Medical, Aliso Viejo, California, USA). We retrospectively identified all patients treated with a WEB DL between November 2010 and February 2013 in 2 hospitals. The IA occlusion was graded on follow-up CE-MRA and DSA by 4 independent readers and by 2 readers reaching a consensus, respectively. Interobserver agreement for MRA and intertechnique agreement was evaluated by calculating linear weighted κ. Fifteen patients with 16 IAs were included. Mean delay between MRA and DSA was 2 months (range 0-16 months). Interobserver agreement for MRA was substantial to almost perfect (κ=0.686-0.921; mean κ=0.809). Intertechnique agreement was moderate to substantial (κ=0.579-0.724; mean κ=0.669). Only three out of five inadequately occluded IAs were detected by MRA. CE-MRA is a useful tool for the follow-up of IAs treated with a WEB DL. However, early follow-up with DSA remains mandatory to detect inadequately occluded IAs. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Pilzinfektionen des Zentralnervensystems bei immunkompetentem Wirt

NARCIS (Netherlands)

Tintelnot, K.; de Hoog, G.S.; Haase, G.

2014-01-01

Die Mehrzahl von Pilzinfektionen, die zu mykotischen Tumoren führen und bei Patienten ohne jegliche prädisponierende Vorerkrankung auftreten, wird durch Cryptococcus gattii bzw. C. neoformans oder durch Schwärzepilze, insbesondere durch Cladophialophora bantiana, Ramichloridium mackenziei, Exophiala

Kontrastmittelverstärkte Magnet-Resonanz-Urographie unter forcierter Diurese - Stellenwert in der Differentialdiagnostik bei Obstruktionen des oberen Harntraktes

Directory of Open Access Journals (Sweden)

Jung P

2001-01-01

Full Text Available Die Magnet-Resonanz-Urographie (MRU ist ein relativ neues Verfahren in der Diagnostik des oberen Harntraktes. Das Ziel dieser Studie war der Vergleich der Aussagefähigkeit der MRU unter Gabe von Gadolinium und Furosemid und dem konventionellen Urogramm (IVU in der Diagnostik der Ursache von Obstruktionen im Bereich des Harnleiters. 82 Patienten mit im IVU nachgewiesener Obstruktion des oberen Harntraktes oder urographisch stummer Niere bei sonographisch nachgewiesener Dilatation wurden der MRU zugeführt. Die Bilder beider Untersuchungsmethoden wurden von voneinander unabhängigen Untersuchern befundet. Zwei Urologen befundeten die IVU-Bilder, zwei Radiologen die MRU-Bilder, die Radiologen kannten die IVU-Diagnose nicht. Bei unklarer Diagnose wurden weitere Untersuchungen wie Computertomographie, retrograde Pyelographie oder Ureteroskopie durchgeführt. Die Diagnosen waren: Harnleitersteine bei 72 Patienten, Harnleitertumore bei 8 Patienten und extraureterale Tumore bei 2 Patienten. Eine richtige Diagnose bei den Steinpatienten wurde durch IVU bei 49 von 72 Patienten und durch MRU bei 64 von 72 Patienten gestellt. In dieser Patientengruppe wurden durch die MRU zwei falsche Diagnosen gestellt. Fehlende Kontrastmittelausscheidung war der Hauptgrund für Versagen der IVU. 3 der 8 Patienten mit Harnleitertumoren wurden durch die IVU richtig dignostiziert, bei dreien wurde eine falsche Diagnose gestellt. Durch die MRU konnten in dieser Gruppe 7 von 8 Patienten korrekt diagnostiziert werden, es wurde keine falsche Diagnose erhoben. IVU wird zunächst die Standarduntersuchungstechnik zur Darstellung des oberen Harntraktes bleiben, aber durch diese Studie konnte die Möglichkeit gezeigt werden, die in der MRU in Kombination mit Gadolinium und Furosemid liegt. Die größte Bedeutung dieser Untersuchung liegt in der urographisch stummen Niere, bei Untersuchungen in der Schwangerschaft, bei Kindern und bei Patienten mit Kontrastmittelunverträglichkeit.

Kulturspezifische Elemente und ihre Problematik bei der Filmsynchronisierung

Directory of Open Access Journals (Sweden)

Prof. Dr. Carmen Cuéllar Lázaro

2013-07-01

Full Text Available Bei der Untersuchung der Übersetzungsproblematik von kulturspezifischen Elementen geht es darum, diese Konzepte begrifflich abzugrenzen, inhaltlich und sprachlich zu klassifizieren sowie die Problematik ihrer Übersetzung zu beschreiben. Bei der Filmsynchronisierung sind außerdem die Merkmale und besonderen Bedingungen des Mediums und des audiovisuellen Textes zu berücksichtigen. Die Zielsetzung dieser Studie ist, die Übersetzung von kulturspezifischen Elementen der Filmsynchronisierung (Deutsch-Spanisch zu analysieren. Wir schlagen ein Zwei-Ebenen-Modell vor: Die erste Ebene berücksichtigt die Art der erfahrenen sprachlichen Bearbeitung. Auf der zweiten Ebene wird die kulturelle Orientierung der Ergebnisse untersucht. Danach werden einige Schlussfolgerungen aus der spanischen Synchronfassung gezogen.

Kulturspezifische Elemente und ihre Problematik bei der Filmsynchronisierung

Directory of Open Access Journals (Sweden)

Prof. Dr. Carmen Cuéllar Lázaro

2013-07-01

Full Text Available Bei der Untersuchung der Übersetzungsproblematik von kulturspezifischen Elementen geht es darum, diese Konzepte begrifflich abzugrenzen, inhaltlich und sprachlich zu klassifizieren sowie die Problematik ihrer Übersetzung zu beschreiben. Bei der Filmsynchronisierung sind außerdem die Merkmale und besonderen Bedingungen des Mediums und des audiovisuellen Textes zu berücksichtigen.   Die Zielsetzung dieser Studie ist, die Übersetzung von kulturspezifischen Elementen der Filmsynchronisierung (Deutsch-Spanisch zu analysieren. Wir schlagen ein Zwei-Ebenen-Modell vor: Die erste Ebene berücksichtigt die Art der erfahrenen sprachlichen Bearbeitung. Auf der zweiten Ebene wird die kulturelle Orientierung der Ergebnisse untersucht. Danach werden einige Schlussfolgerungen aus der spanischen Synchronfassung gezogen.

Diagnosis of renal artery stenosis : spiral CTA vs. IA-DSA

International Nuclear Information System (INIS)

Kim, Tae Sung; Chung, Jin Wook; Park, Jae Hyung; Kim, Seung Hyup; Yeon, Kyung Mo; Han, Man Chung

1996-01-01

To evaluate the accuracy of spiral CT angiography(CTA) in the demonstration of accessory or multiple renal arteries and renal artery stenosis. We prospectively performed CTA in 50 patients (24 males and 26 females) between nine and 77 years old (mean 39.3) in whom renovascular hypertension was suspected (n=32), or who were potential renal donors (n=18). Within two days of CTA, intraarterial digital subtraction angiography(IA-DSA) was performed. Both spiral CTA and IA-DSA images were blindly compared by two radiologists with respect to the number of accessory renal arteries and the location and severity of renal artery stenosis. The severity of renal arterial stenosis was graded with a five-point scale (grades 0-4). CTA demonstrated 26 of total 27 accessory renal arteries (detection rate=96.5%). For the diagnosis of grade 2-4 stenosis (≥50% stenosis) (n=40 of a total of 127 renal arteries), the sensitivity, specificity, and accuracy of CTA were 90%, 96.5%, and 94.5%, respectively. For the detection of grade 3-4 stenoses (≥75% stenosis) (n=33), the sensitivity, specificity, and accuracy of CTA were 87.9%, 98.9%, and 96.1%, respectively. For the detection of grade 3-4 stenoses in the main renal artery (n=27), the sensitivity, specificity, and accuracy of CTA were 96.3%, 100%, and 99.0%, respectively. Spiral CTA is a reliable and accurate screening modality for the evaluation of renal artery in patients suspected to be suffering from renovascular hypertension, or who are potential renal donors

Hemodynamic study of cervical carotid arteries using DSA

International Nuclear Information System (INIS)

Kumashiro, Masayuki; Araki, Osamu; Matsunaga, Morio; Shigeyasu, Makio

1986-01-01

Although intravenous digital subtraction angiography (IVDSA) has been widely utilized as a means of morphological examination for the detection of intracranial or extracranial vascular lesions, it has thus for contributed little to quantitative assessment in hemodynamics. In the present study, a fundamental analysis of the hemodynamics on the cervical carotid artery was performed with a relative perfusion efficiency (Rath et al., 1979). This was not related to the measurement of time, such as the mean transit time, but was based on Sapirstein's principle. After the intravenous administration of the contrast material, dynamic DSA was performed using our equipment, Shimadzu DAR-100. After setting the region of interest in common carotid arteries on DSA images by means of a microdensitometer (Sakura PDS-15) combined with a computer (NEC ACOS-460), time-density curves were obtained on both sides. Thereafter, the RPE was calculated as a ratio of two integrals from the zero time to the earlier peak time of the time-density curves with respect to the time. The flow model with the hydro-dynamic system was used to detect the relationship between the RPEs and the ratios of the actual flows in the system. The results of this experiment showed a high correlation between the RPEs and the flows (r = 0.85, p < 0.001). In normal subjects (n = 28), the mean of the RPEs was 1.07 ± 0.27 (S.D.). The RPEs showed significantly lower values in the 5 patients with severe stenosis of the internal carotid artery (0.76 ± 0.15, p < 0.02), as well as even more significantly lower values in the 9 patients with a complete occlusion of the internal carotid artery (0.64 ± 0.19, p < 0.001). The RPE measurement with IVDSA has been shown to be useful for recognizing the cervical hemodynamic changes in patients with occlusive cervicovascular disease. (author)

Successive approximation algorithm for cancellation of artifacts in DSA images

International Nuclear Information System (INIS)

Funakami, Raiko; Hiroshima, Kyoichi; Nishino, Junji

2000-01-01

In this paper, we propose an algorithm for cancellation of artifacts in DSA images. We have already proposed an automatic registration method based on the detection of local movements. When motion of the object is large, it is difficult to estimate the exact movement, and the cancellation of artifacts may therefore fail. The algorithm we propose here is based on a simple rigid model. We present the results of applying the proposed method to a series of experimental X-ray images, as well as the results of applying the algorithm as preprocessing for a registration method based on local movement. (author)

Effects of spin-orbit coupling on laser cooling of BeI and MgI

Energy Technology Data Exchange (ETDEWEB)

Wan, Mingjie, E-mail: wanmingjie1983@sina.com; Huang, Duohui; Shao, Juxiang; Li, Yuanyuan [Computational Physics Key Laboratory of Sichuan Province, Yibin University, Yibin 644007 (China); Yu, You [College of Optoelectronic Technology, Chengdu University of Information Technology, Chengdu 610225 (China); Li, Song [College of Physical Science and Technology, Yangtze University, Jingzhou 434023 (China)

2015-10-28

We present the ab initio study of spin-orbit coupling effects on laser cooling of BeI and MgI molecules. Potential energy curves for the X{sup 2}Σ{sup +}{sub 1/2}, A{sup 2}Π{sub 1/2,3/2}, and 2{sup 2}Π{sub 3/2,1/2} states are calculated using multi-reference configuration interaction method plus Davidson corrections. Spectroscopic parameters of BeI and MgI are in excellent agreement with available experimental and theoretical values. The A{sup 2}Π{sub 3/2} state of MgI is a repulsive state. It is an unsuitable scheme for the A{sup 2}Π{sub 3/2}(υ′)← X{sup 2}Σ{sup +}{sub 1/2} (υ″) transition for laser cooling of MgI. Highly diagonally distributed Franck-Condon factors f{sub 00} for the A{sup 2}Π{sub 1/2,3/2} (υ′ = 0) ← X{sup 2}Σ{sup +}{sub 1/2} (υ″ = 0) transitions and suitable radiative lifetimes τ for the A{sup 2}Π{sub 1/2,3/2} (υ′ = 0) of BeI and MgI are obtained. Three laser wavelength drives are required for the A{sup 2}Π{sub 1/2,3/2}(υ′)←X{sup 2}Σ{sup +}{sub 1/2} (υ″) transitions of BeI and MgI. The proposed cooling wavelengths of BeI and MgI are both in the violet region. The results imply the feasibility of laser cooling of BeI and MgI, and that laser cooling of BeI is more possible.

Nagelbefall kann bei Patienten mit Psoriasis auf eine Enthesiopathie hinweisen.

Science.gov (United States)

Castellanos-González, Maria; Joven, Beatriz Esther; Sánchez, Julio; Andrés-Esteban, Eva María; Vanaclocha-Sebastián, Francisco; Romero, Pablo Ortiz; Díaz, Raquel Rivera

2016-11-01

Obwohl subklinische Enthesiopathie ein gut etabliertes diagnostisches Merkmal der Psoriasisarthritis (PsA) ist, wird sie häufig übersehen, da viele Patienten asymptomatisch sind. Gäbe es klinische Hinweise auf das Vorliegen einer Enthesiopathie, würde dies den Klinikern die Möglichkeit eröffnen, eine PsA frühzeitig zu diagnostizieren. Es wurde eine monozentrische prospektive Studie mit insgesamt 90 Psoriasis-Patienten durchgeführt, um mittels Ultraschall das Vorliegen von Enthesenanomalien zu untersuchen und eine Korrelation mit dem Befall der Nägel festzustellen. Enthesenanomalien wurden bei 23 Patienten (25,5 %) gefunden, von denen 19 (82,6 %) Nagelbefall aufwiesen. Bei 4 Patienten waren die Nägel nicht betroffen. Enthesiopathie lag bei 31,1 % (19/61) der Patienten mit Onychopathie vor, von den Patienten ohne Nagelbefall litten nur 13,8 % (4/29) an Enthesiopathie (p = 0,07). Zwischen dem Target-NAPSI-Score und dem Vorliegen einer Enthesiopathie bestand eine signifikante Korrelation. Eine signifikante Korrelation bestand darüber hinaus auch zwischen dem Vorliegen einer Enthesiopathie und der Anzahl der betroffenen Nägel (p = 0,035). Klinische Belege für eine Onychopathie können der Schlüssel für die frühe Diagnose einer Enthesiopathie bei Psoriasis-Patienten sein. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

The effect of the signal-to-noise ratio and window width on image information in intravenous DSA of various vascular regions

International Nuclear Information System (INIS)

Arlart, I.P.; Ertel, R.; Siemens A.G., Erlangen

1986-01-01

The diagnostic quality of DSA images depends on numerous factors related to the apparatus and the technique of examination. An improvement in image can be brought about by correct choice of the mask and injected frames, by subsequent correct manipulation of the images and by the choice of the signal-to-noise ratio and window width. In the present study, the effect of these factors was demonstrated on image quality of venous DSA studies in various vascular regions. Practical advice is given for the examination of particular regions and for various diagnostic problems. (orig.)

PET in diagnosing exocrine pancreatic cancer; PET bei Tumoren des exokrinen Pankreas

Energy Technology Data Exchange (ETDEWEB)

Bares, R.; Besenfelder, H.; Dohmen, B.M. [Abt. Nuklearmedizin, Radiologische Klinik des Universitaetsklinikums Tuebingen (Germany)

2003-06-01

Despite dramatic improvements in diagnostic imaging (ultrasonography, in particular endoscopic ultrasound, CT, MRI) treatment results of pancreatic cancer are still poor. Due to the lack of early symptoms, most tumors are diagnosed at an advanced stage of disease which excludes curative surgical treatment. FDG-PET has been shown to be effective in detecting pancreatic cancer as well as differentiating benign from malignant pancreatic tumors. Results might be further improved by applying quantitative analyses, in particular kinetic modelling of FDG metabolism. Nevertheless false negative as well as false positive findings may occur. Small lesions (lymphnode or liver metastases < 1 cm) might be missed, furthermore hyperglycemia often present in patients with pancreatic disease might reduce tumor uptake and subsequently tumor detectability by PET. False positive findings were reported in active pancreatitis and some benign tumors. Although PET proved to be superior to CT or ERCP in detecting cancer, clinical relevance of PET is limited due to the absence of therapeutic consequences to be derived from PET. As a consequence PET should only be used in patients with equivocal findings of morphological imaging (CT, ERCP) who are potential candidates for surgical treatment. (orig.) [German] Trotz verbesserter diagnostischer Moeglichkeiten (endoskopischer Ultraschall, Spiral-CT, MRT) sind die Behandlungsergebnisse bei Tumoren des exokrinen Pankreas nach wie vor unbefriedigend. Aufgrund der spaet einsetzenden klinischen Symptomatik wird die Diagnose meist erst bei lokaler Inoperabilitaet gestellt. Die FDG-PET has sich sowohl im Nachweis von Pankreaskarzinomen als auch bei der Differenzialdiagnose pankreatischer Raumforderungen bewaehrt und den etablierten bildgebenden Verfahren (Ultraschall, CT) als ueberlegen erwiesen. Weitere Verbesserungen erscheinen durch absolute Quantifizierung der FDG-Kinetik moeglich. Dennoch koennen falsch negative wie auch falsch positive Ergebnisse

Diagnostic accuracy of dual energy CT angiography in patients with diabetes mellitus; Diagnostische Genauigkeit der Dual-energy-CT-Angiographie bei Patienten mit Diabetes mellitus

Energy Technology Data Exchange (ETDEWEB)

Schabel, C.; Bongers, M.N.; Syha, R. [Klinikum der Eberhard-Karls-Universitaet, Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Klinikum der Eberhard-Karls-Universitaet, Sektion fuer Experimentelle Radiologie der Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Ketelsen, D.; Homann, G.; Notohamiprodjo, M.; Nikolaou, K.; Bamberg, F. [Klinikum der Eberhard-Karls-Universitaet, Abteilung fuer Diagnostische und Interventionelle Radiologie, Tuebingen (Germany); Thomas, C. [Universitaetsklinikum Duesseldorf, Abteilung fuer Diagnostische und Interventionelle Radiologie, Duesseldorf (Germany)

2015-04-01

Herausforderung dar. Ziel dieser Arbeit war die Ermittlung der diagnostischen Genauigkeit der Dual-energy-CT-Angiographie (DE-CTA) im Vergleich zum Goldstandard, der invasiven digitalen Subtraktionsangiographie (DSA) bei der Stenoseerkennung, da die DE-CTA potenziell eine Differenzierung von Verkalkungen und jodhaltigem Kontrastmittel ermoeglicht. Dreissig Patienten mit dem Verdacht auf das Vorliegen oder bekannter PAVK und zusaetzlich bestehendem Diabetes mellitus wurden retrospektiv in die Studie eingeschlossen. Bei allen Teilnehmern wurde eine DE-CTA (Somatom Definition Flash, Siemens Healthcare, Germany), gefolgt von einer invasiven Angiographie durchgefuehrt. Das Vorhandensein von Stenosen in gekruemmten multiplanaren Reformationen (MPR) und Projektionen maximaler Intensitaet (MIP) wurde verblindet evaluiert. Die diagnostische Genauigkeit wurde mit der Angiographie als Goldstandard errechnet. Bei den 30 in die Analyse eingeschlossenen diabetischen Patienten (83 % maennlich, 70,0 ± 10,5 Jahre alt, 83 % Diabetes mellitus Typ 2) war die Praevalenz behandlungsbeduerftiger Stenosen in 331 evaluierten Gefaesssegmenten hoch (30 %). Die DE-CTA detektierte kritische Stenosen mit einer hohen Sensitivitaet und guten Spezifitaet anhand gekruemmter MPR (100 und 93,1 %) und MIP (99 und 91,8 %). In einer Subanalyse war die diagnostische Genauigkeit am hoechsten fuer Stenosen im Bereich der Beckenstrombahn (gekruemmte MPR 97,1 % vs. MIP 100 %) und im Oberschenkelbereich (99,2 vs. 96,6 %) verglichen mit dem Unterschenkelkompartiment (90,9 vs. 88 %). Die DE-CTA weist eine hohe diagnostische Genauigkeit bei der Stenosenerkennung und -charakterisierung im Rahmen der PAVK bei Patienten mit Diabetes mellitus auf, hat jedoch eine eingeschraenkte Genauigkeit im Bereich des Unterschenkelkompartiments. (orig.)

MR spectroscopy in dementia; MR-Spektroskopie bei Demenz

Energy Technology Data Exchange (ETDEWEB)

Hauser, T.; Gerigk, L.; Giesel, F.; Schuster, L.; Essig, M. [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg, Abteilung E010, Radiologie, Heidelberg (Germany)

2010-09-15

With an increasingly aging population we are faced with the problem of an increasing number of dementia patients. In addition to clinical, neuropsychological and laboratory procedures, MRI plays an important role in the early diagnosis of dementia. In addition to various morphological changes functional changes can also help in the diagnosis and differential diagnosis of dementia. Overall the diagnosis of dementia can be improved by using parameters from MR spectroscopy. This article focuses on MR spectroscopic changes in the physiological aging process as well as on changes in mild cognitive impairment a precursor of Alzheimer's dementia, in Alzheimer's dementia, frontotemporal dementia, vascular dementia and Lewy body dementia. (orig.) [German] Angesichts einer immer aelter werdenden Bevoelkerung sind wir mit dem Problem einer zunehmenden Zahl an Demenzerkrankungen konfrontiert. Neben klinischen, neuropsychologischen und laborchemischen Verfahren spielt die MRT zur Fruehdiagnostik einer Demenz eine wichtige Rolle. Morphologische Veraenderungen wie auch verschiedene funktionelle Verfahren helfen bei der Diagnostik und Differenzialdiagnostik einer Demenz. Insgesamt kann mittels MR-spektroskopischer Parameter die Diagnostik einer Demenz verbessert werden. In diesem Artikel soll auf MR-spektroskopische Veraenderungen im Rahmen des physiologischen Alterungsprozesses eingegangen werden. Ferner werden speziell Veraenderungen bei leichter kognitiver Beeintraechtigung, einer Vorform der Alzheimer-Demenz, bei Alzheimer-, frontotemporaler, vaskulaerer und Lewy-Koerper-Demenz eroertert. (orig.)

Brain arteriovenous malformation diagnosis: value of time-resolved contrast-enhanced MR angiography at 3.0T compared to DSA

International Nuclear Information System (INIS)

Machet, A.; Kadziolka, K.; Robin, G.; Lanoix, O.; Pierot, L.; Portefaix, C.

2012-01-01

This study was conducted in order to evaluate the value of time-resolved contrast-enhanced magnetic resonance angiography (TR-CE-MRA) with a 3.0-T magnetic field compared to digital subtraction angiography (DSA) as the reference standard for the diagnosis of brain arteriovenous malformation (bAVM). Nineteen patients with 19 angiographically confirmed untreated bAVM were investigated with both DSA and TR-CE-MRA for the initial diagnosis. Examinations were compared by two independent readers. Interobserver agreement and intermodality agreement with respect to nidus size, arterial feeders, and venous drainage were determined using the K statistic test. Also, the quality of the TR-CE-MRA images was evaluated. Seventeen of the 19 bAVM (89.5%) detected with DSA were diagnosed with TR-CE-MRA. Interobserver agreement for TR-CE-MRA was good for nidus size, venous drainage, and arterial feeders (K = 0.75, 95% CI 0.50-1.00; K = 0.77, 95% CI 0.54-1.00; and K = 0.80, 95% CI 0.59-1.00 respectively). Intermodality agreement was good for nidus size and venous drainage (K = 0.75, 95% CI 0.49-1.00 and K = 0.77, 95% CI 0.54-1.00, respectively) and moderate for arterial feeders (K = 0.44, 95% CI 0.17-0.70). TR-CE-MRA at 3.0 T has a good sensitivity for bAVM detection and good agreement with DSA for determining nidus size and the type of venous drainage, suggesting that TR-CE-MRA is potentially a reliable tool for the diagnosis and assessment of bAVMs. However, it still suffers from low spatial resolution and vessel superposition, making differentiation of the arterial feeders of the nidus difficult at times. (orig.)

Behandlung von Herzrhythmusstörungen mit Magnesium bei Patienten mit Herzinsuffizienz

Directory of Open Access Journals (Sweden)

Wink K

2002-01-01

Full Text Available Die medikamentöse Behandlung von Herzrhythmusstörungen ist unbefriedigend, da bei guter Wirksamkeit durch die Proarrhythmie eine Verbesserung der Prognose gefährdet und nicht gesichert ist. Man kann davon ausgehen, daß Magnesiumsalze keine arrhythmogene Effekte aufweisen. Bei Patienten mit einer Herzinsuffizienz besteht häufig ein Mg-Mangel, der durch gastrointestinale Störungen, neurohormonale Regulationen, aber auch durch die Therapie (Diuretika,Digitalisbedingt ist. An Patienten mit einer Herzinsuffizienz müßte sich demnach zeigen lassen, ob die Mg-Substitution einen antiarrhythmischen Effekt aufweist. In fünf placebokontrollierten Studien konnte gezeigt werden, daß sich teil weise signifikant und mit ausreichen der Aussagekraft (PowerArrhythmien bei Patienten mit Herzinsuffizienz durch orale und parenterale Gabe von Mg-Salzen reduzieren lassen. Trotz Einschränkungen wie z.B. inadäquates Design, fehlende Vermeidung von Bias, ungenügende Vergleichbarkeit der Behandlungsgruppen, inadäquate Auswertung und ungenügende Berücksichtigung der Spontanvariation läßt sich aufgrund der Ergebnisse der Studien die Hypothese aufstellen, daß Magnesiumsalze bei Patienten mit Herzinsuffizienz Herzrhythmusstörungen günstig beeinflussen können. Prospektive, randomisierte,verblindete und kontrollierte konfirmatorische Studien mit ausreichenden Fallzahlen sind jedoch notwendig, um diese Hypothese zu bestätigen.

"Updates to Model Algorithms & Inputs for the Biogenic Emissions Inventory System (BEIS) Model"

Science.gov (United States)

We have developed new canopy emission algorithms and land use data for BEIS. Simulations with BEIS v3.4 and these updates in CMAQ v5.0.2 are compared these changes to the Model of Emissions of Gases and Aerosols from Nature (MEGAN) and evaluated the simulations against observatio...

Introduction to the principles of Digital Subtraction Angiography (DSA)

Energy Technology Data Exchange (ETDEWEB)

Kaplanis, P [Medical Physics Department, Nicosia General Hospital, Nicosia (Cyprus)

1998-12-31

Medical applications of advanced technology have rapidly become more sophisticated and more widespread. The field of diagnostic imaging is by no means an exception. There has been a number of breathtaking developments in the field of medical imaging in recent years. Today higher quality, greater clarity and more minute precision are considered not advantages but necessities. Hence new developments are concentrated in the data acquisition and image processing based on the microprocessor controlled modules interfaced with state of the art radiological imaging equipment. One such development is the subtraction of x-rays vis a computer for better visualization of blood vessels, cavities of the heart and of the coronary and pulmonary vascular system. This procedure is termed Digital Subtraction Angiography (DSA). (author). 5 refs, 3 figs.

Introduction to the principles of Digital Subtraction Angiography (DSA)

International Nuclear Information System (INIS)

Kaplanis, P.

1997-01-01

Medical applications of advanced technology have rapidly become more sophisticated and more widespread. The field of diagnostic imaging is by no means an exception. There has been a number of breathtaking developments in the field of medical imaging in recent years. Today higher quality, greater clarity and more minute precision are considered not advantages but necessities. Hence new developments are concentrated in the data acquisition and image processing based on the microprocessor controlled modules interfaced with state of the art radiological imaging equipment. One such development is the subtraction of x-rays vis a computer for better visualization of blood vessels, cavities of the heart and of the coronary and pulmonary vascular system. This procedure is termed Digital Subtraction Angiography (DSA). (author)

MRI for myocarditis; MRT bei Myokarditis

Energy Technology Data Exchange (ETDEWEB)

Gutberlet, M.; Luecke, C.; Krieghoff, C.; Hildebrand, L.; Steiner, J.; Adam, J.; Grotthoff, M.; Lehmkuhl, L. [Herzzentrum, Universitaet Leipzig, Abteilung fuer Diagnostische und Interventionelle Radiologie, Leipzig (Germany); Lurz, P.; Eitel, I.; Thiele, H. [Herzzentrum, Universitaet Leipzig, Abteilung Kardiologie, Leipzig (Germany)

2013-01-15

Cardiovascular magnetic resonance imaging (CMRI) has become the primary tool for the non-invasive assessment in patients with suspected myocarditis, especially after exclusion of acute coronary syndrome (ACS) for the differential diagnosis. Various MRI parameters are available which have different accuracies. Volumetric and functional ventricular assessment and the occurrence of pericardial effusion alone demonstrate only a poor sensitivity and specificity. The calculation of the T2-ratio (edema assessment), the early or global relative myocardial enhancement (gRE) and the late gadolinium enhancement (LGE), which represents irreversibly injured myocardium, are more specific parameters. All MRI parameters demonstrate the best accuracy in infarct-like acute myocarditis, whereas in chronic myocarditis sensitivity and specificity are less accurate. Therefore, a multisequential (at least two out of three parameters are positive) approach is recommended. The assessment of the value of newer, more quantitative MRI sequences, such as T1 and T2-mapping is still under investigation. (orig.) [German] Die kardiale MRT stellt die primaere nichtinvasive bildgebende Modalitaet bei Verdacht auf Myokarditis dar, insbesondere auch nach Ausschluss eines akuten Koronarsyndroms (ACS) zur Differenzialdiagnose. Verschiedene MR-Parameter mit unterschiedlicher Wertigkeit stehen zur Verfuegung. Die Beurteilung der Volumetrie und Ventrikelfunktion weisen ebenso wie der Nachweis eines Perikardergusses alleine nur eine geringe Sensitivitaet und Spezifitaet auf. Die spezifischeren MRT-Inflammationsparameter stellen die T2-Ratio (Oedemnachweis), die fruehe Kontrastmittelanreicherung bzw. das globale relative Enhancement (gRE) und die spaete Kontrastmittelanreicherung, das so genannte Late-Gadolinium-Enhancement (LGE) als Zeichen eines irreversiblen Myokardschadens dar. Alle MR-Parameter zeigen die beste diagnostische Genauigkeit bei einer ''infarktaehnlichen'' akuten

Radiotherapy for treatment of induratio penis plastica; Strahlentherapie bei Induratio penis plastica

Energy Technology Data Exchange (ETDEWEB)

Bruns, F.; Kardels, B.; Schaefer, U.; Schoenekaes, K.; Willich, N. [Westfaelische Wilhelms-Univ., Muenster (Germany). Klinik und Poliklinik fuer Strahlentherapie-Radioonkologie

1999-06-01

Radiotherapy is shown to be an effective, low-cost and non-invasive modality for treatment of induratio penis plastica. Its efficiency could be proven especially for inflammatory stages of the disease, or as an alternative after failure of conventional treatment. A total dose of no more than 20-25 Gy was found to achieve clear improvements in two thirds of the patients treated, while avoiding at the same time cosmetically disadvantageous late effects. (orig./CB) [Deutsch] Die Strahlentherapie ist eine wirksame, kostenguenstige und nicht-invasive Behandlungsmoeglichkeit bei Induratio penis plastica. Ihren Stellenwert konnte sie insbesondere im inflammatorischen Stadium und nach Versagen anderer konservativer Therapieansaetze zeigen. Eine Gesamteinstrahldosis von 20-25 Gy reicht aus, um bei 2/3 der Patienten eine deutliche Besserung der Symptomatik zu erzielen bei gleichzeitiger Vermeidung kosmetisch relevanter Spaetnebenwirkungen. (orig.)

Assessment and treatment planning of lateral intracranial dural arteriovenous fistulas in 3 T MRI and DSA: A detailed analysis under consideration of time-resolved imaging of contrast kinetics (TRICKS) and ce-MRA sequences

Energy Technology Data Exchange (ETDEWEB)

Ertl, L.; Brueckmann, H.; Patzig, M.; Brem, C.; Forbrig, R.; Fesl, G. [Ludwig-Maximilians-University, Grosshadern Campus, Department of Neuroradiology, Institute of Clinical Radiology, Munich (Germany); Kunz, M. [Ludwig-Maximilians-University, Grosshadern Campus, Department of Neurosurgery, Munich (Germany)

2016-12-15

The current gold standard in the assessment of lateral intracranial dural arteriovenous fistulas (LDAVF) is digital subtraction angiography (DSA). However, magnetic resonance imaging (MRI) is a non-invasive emerging tool for the evaluation of such lesions. The aim of our study was to compare the DSA to our 3 T MR-imaging protocol including a highly spatial resolved (ce-MRA) and a temporal resolved (''time-resolved imaging of contrast kinetics'', TRICKS) contrast-enhanced MR angiography to evaluate if solely DSA can remain the gold-standard imaging modality for the treatment planning of LDAVF. We retrospectively reviewed matched pairs of DSA and 3 T MRI examinations of 24 patients with LDAVF (03/2008-04/2014) by the same list of relevant criteria for an endovascular LDAVF treatment planning. In particular, we determined intermodality agreement for the Cognard classification, the identifeication of arterial feeders, and the detailed assessment of each venous drainage pattern. Intermodality agreement for the Cognard classification was excellent (k = 1.0). Whereas MRI failed in identifying small arterial feeders, it was superior to the DSA in the assessment of the sinus and the venous drainage pattern. The combination of MRI and DSA is the new gold standard in LDAVF treatment planning. (orig.)

Electrochemical oxidation of bio-refractory dye in a simulated textile industry effluent using DSA electrodes in a filter-press type FM01-LC reactor.

Science.gov (United States)

Rodríguez, Francisca A; Mateo, María N; Aceves, Juan M; Rivero, Eligio P; González, Ignacio

2013-01-01

This work presents a study on degradation of indigo carmine dye in a filter-press type FM01-LC reactor using Sb2O5-doped Ti/IrO2-SnO2 dimensionally stable anode (DSA) electrodes. Micro- and macroelectrolysis studies were carried out using solutions of 0.8 mM indigo carmine in 0.05 M NaCl, which resemble blue denim laundry industrial wastewater. Microelectrolysis results show the behaviour of DSA electrodes in comparison with the behaviour of boron-doped diamond (BDD) electrodes. In general, dye degradation reactions are carried out indirectly through active chlorine generated on DSA, whereas in the case of BDD electrodes more oxidizing species are formed, mainly OH radicals, on the electrode surface. The well-characterized geometry, flow pattern and mass transport of the FM01-LC reactor used in macroelectrolysis experiments allowed the evaluation of the effect of hydrodynamic conditions on the chlorine-mediated degradation rate. Four values of Reynolds number (Re) (93, 371, 464 and 557) at four current densities (50, 100, 150 and 200 A/m2) were tested. The results show that the degradation rate is independent of Re at low current density (50 A/m2) but becomes dependent on the Re at high current density (200 A/m2). This behaviour shows the central role of mass transport and the reactor parameters and design. The low energy consumption (2.02 and 9.04 kWh/m3 for complete discolouration and chemical oxygen demand elimination at 50 A/m2, respectively) and the low cost of DSA electrodes compared to BDD make DSA electrodes promising for practical application in treating industrial textile effluents. In the present study, chlorinated organic compounds were not detected.

Just in Time DSA-The Hanford Nuclear Safety Basis Strategy

Energy Technology Data Exchange (ETDEWEB)

Olinger, S. J.; Buhl, A. R.

2002-02-26

The U.S. Department of Energy, Richland Operations Office (RL) is responsible for 30 hazard category 2 and 3 nuclear facilities that are operated by its prime contractors, Fluor Hanford Incorporated (FHI), Bechtel Hanford, Incorporated (BHI) and Pacific Northwest National Laboratory (PNNL). The publication of Title 10, Code of Federal Regulations, Part 830, Subpart B, Safety Basis Requirements (the Rule) in January 2001 imposed the requirement that the Documented Safety Analyses (DSA) for these facilities be reviewed against the requirements of the Rule. Those DSA that do not meet the requirements must either be upgraded to satisfy the Rule, or an exemption must be obtained. RL and its prime contractors have developed a Nuclear Safety Strategy that provides a comprehensive approach for supporting RL's efforts to meet its long term objectives for hazard category 2 and 3 facilities while also meeting the requirements of the Rule. This approach will result in a reduction of the total number of safety basis documents that must be developed and maintained to support the remaining mission and closure of the Hanford Site and ensure that the documentation that must be developed will support: compliance with the Rule; a ''Just-In-Time'' approach to development of Rule-compliant safety bases supported by temporary exemptions; and consolidation of safety basis documents that support multiple facilities with a common mission (e.g. decontamination, decommissioning and demolition [DD&D], waste management, surveillance and maintenance). This strategy provides a clear path to transition the safety bases for the various Hanford facilities from support of operation and stabilization missions through DD&D to accelerate closure. This ''Just-In-Time'' Strategy can also be tailored for other DOE Sites, creating the potential for large cost savings and schedule reductions throughout the DOE complex.

Just in Time DSA-The Hanford Nuclear Safety Basis Strategy

International Nuclear Information System (INIS)

Olinger, S. J.; Buhl, A. R.

2002-01-01

The U.S. Department of Energy, Richland Operations Office (RL) is responsible for 30 hazard category 2 and 3 nuclear facilities that are operated by its prime contractors, Fluor Hanford Incorporated (FHI), Bechtel Hanford, Incorporated (BHI) and Pacific Northwest National Laboratory (PNNL). The publication of Title 10, Code of Federal Regulations, Part 830, Subpart B, Safety Basis Requirements (the Rule) in January 2001 imposed the requirement that the Documented Safety Analyses (DSA) for these facilities be reviewed against the requirements of the Rule. Those DSA that do not meet the requirements must either be upgraded to satisfy the Rule, or an exemption must be obtained. RL and its prime contractors have developed a Nuclear Safety Strategy that provides a comprehensive approach for supporting RL's efforts to meet its long term objectives for hazard category 2 and 3 facilities while also meeting the requirements of the Rule. This approach will result in a reduction of the total number of safety basis documents that must be developed and maintained to support the remaining mission and closure of the Hanford Site and ensure that the documentation that must be developed will support: compliance with the Rule; a ''Just-In-Time'' approach to development of Rule-compliant safety bases supported by temporary exemptions; and consolidation of safety basis documents that support multiple facilities with a common mission (e.g. decontamination, decommissioning and demolition [DD and D], waste management, surveillance and maintenance). This strategy provides a clear path to transition the safety bases for the various Hanford facilities from support of operation and stabilization missions through DD and D to accelerate closure. This ''Just-In-Time'' Strategy can also be tailored for other DOE Sites, creating the potential for large cost savings and schedule reductions throughout the DOE complex

Untersuchungen zum Riechvermögen bei Patienten mit schizophrenen Störungen

OpenAIRE

Minovi, A; Dombrowski, T; Brüne, M; Dazert, S; Juckel, G

2014-01-01

Einleitung: Riechstörungen werden bei Patienten mit einer Schizophrenie in vielen Studien beschrieben. Im Rahmen einer prospektiv angelegten Studie untersuchten wir das Riechvermögen von 18 Patienten mit einer Schizophrenie im Vergleich zu einer Kontrollgruppe (n=13). Weiterhin erfolgte eine immunhistochemische Untersuchung der Riechschleimhaut bei 8 Patienten mit einer Schizophrenie.Methoden: Die Riechprüfung erfolgte mit Hilfe der erweiterten Sniffin' Sticks-Testbatterie. Nach Biopsie der...

Automated tracking of the vascular tree on DSA images

International Nuclear Information System (INIS)

Alperin, N.; Hoffmann, K.R.; Doi, K.

1990-01-01

Determination of the vascular tree structure is important for reconstruction of three-dimensional vascular tree from biplane images, for assessment of the significance of a lesion, and for planning treatment for arteriovenous malformation. To automate these analyses, the authors of this paper are developing a method to determine the vascular tree structure from digital subtraction angiography (DSA) images. The authors have previously described a vessel tracking method, based on the double-square-box technique. To improve the tracking accuracy, they have developed and integrated with the previous method a connectivity test and guided-sector-search technique. The connectivity test, based on region growing techniques, eliminates tracking across nonvessel regions. The guided sector-search method incorporates information from a larger are of the image to guide the search for the next tracking point

Evaluation of the carotid and vertebral arteries: comparison of 3D SCTA and IA-DSA-work in progress

International Nuclear Information System (INIS)

Seemann, M.D.; Minx, C.; Heuck, A.; Reiser, M.F.; Englmeier, K.H.; Schuhmann, D.R.G.; Fuerst, H.

1999-01-01

Objective: The purpose of this study was to develop a method for three-dimensional (3D) visualization of the whole vascular system of the carotid and vertebral arteries using spiral computed tomographic angiography (SCTA), that allows accurate, qualitative and quantitative evaluation, of anatomical abnormalities, including detection of additional lesions, and estimation of degree of stenosis. Materials and methods: Fifteen patients with anatomical and pathological abnormalities of the arterial vascular system detected by color-coded duplex ultrasound were studied using intraarterial digital subtraction angiography (IA-DSA) with aortic arch injection, and SCTA. The carotid and vertebral arteries were segmented using an interactive threshold interval density volume-growing method and visualized with a color-coded shaded-surface display (SSD) rendering method. The adjacent bone structures were visualized using a transparent volume rendering method. Results: In all cases, the entire volume of the vascular system of the carotid and vertebral arteries could be visualized on SCTA, and the anatomical and pathological abnormalities on 3D SCTA correlated well with that seen on IA-DSA. Conclusion: Results of 3D SCTA had a high degree of correlation with results of IA-DSA in the evaluation of the vascular system of the carotid and vertebral arteries. The 3D SCTA with a subsecond spiral CT scanner is useful for the visualization of anatomical and pathological abnormalities in the circulation in the carotid and vertebral arteries and offer a promising minimally invasive alternative compared with other diagnostic procedures. (orig.) (orig.)

Die Rolle von RANK-Ligand und Osteoprotegerin bei Osteoporose

Directory of Open Access Journals (Sweden)

Hofbauer LC

2004-01-01

Full Text Available Receptor activator of nuclear factor (NF- κB ligand (RANKL, sein zellulärer Rezeptor RANK und der Decoy-Rezeptor Osteoprotegerin (OPG stellen ein essentielles Zytokinsystem für die Zellbiologie von Osteoklasten dar. Verschiedene Untersuchungen belegen die Bedeutung von Störungen des OPG/RANKL/RANK-Systems bei der Pathogenese metabolischer Knochenerkrankungen. In dieser Arbeit werden die wichtigsten Störungen des OPG/RANKL/RANK-Systems bei verschiedenen Osteoporoseformen dargestellt. Östrogenrezeptor- (ER- Agonisten wie 17 β-Östradiol, Raloxifen und Genistein stimulieren die osteoblastäre Produktion von OPG durch Aktivierung von ER- α in vitro, während Lymphozyten von Patientinnen mit Östrogenmangel RANKL überexprimieren. Die parenterale Gabe von OPG vermag den mit Östrogenmangel assoziierten Knochenverlust im Tiermodell und in einer kleineren klinischen Studie zu verhindern. Glukokortikoide und Immunsuppressiva steigern gleichzeitig die RANKL-Expression und hemmen die OPG-Produktion in osteoblastären Zellen in vitro. Glukokortikoide sind auch in vivo imstande, die OPG-Serumspiegel deutlich zu reduzieren. Dagegen hemmen biomechanische Reize in vitro die RANKL-Produktion und steigern die OPG-Produktion. Ein Fehlen dieser biomechanischen Reize bei längerer Immobilisierung kann daher den RANKL/OPG-Quotienten steigern, während die tierexperimentelle Immobilisierungs-Osteoporose durch die parenterale Gabe von OPG gemildert werden kann.

Clinical effectiveness of DSA-guided foam sclerotherapy for varicose veins of lower limbs

International Nuclear Information System (INIS)

Fu Jianhua; He Xu; Chen Guoping; Gu Jianping; Wang Yafei

2011-01-01

Objective: To investigate the clinical effect of DSA-guided foam sclerotherapy for varicose veins of lower limbs. Methods: A total of 25 diseased limbs in 20 patients with varicose veins were treated with foam sclerotherapy. The patients were followed up for six months. Sodium morrhuate, used as the sclerosant, was foamed with air by using Tessari's method, with liquid-gas ratio of 1 : 4. The clinical effectiveness was estimated by CEAP, clinical signs and symptoms. Results: A total of 25 limbs in 20 patients with varicose veins were successfully treated with foam sclerotherapy. The technical success rate was 100%. No serious complications such as pulmonary embolism occurred. Phlebitis was observed in two cases at 2 days 4 days after foam sclerotherapy respectively which was relieved after anti-inflammatory medication for 3 days. At the time of discharge, excellent result was seen in 12 (48%) limbs, good effect in 13 (52%) limbs. The total effective rate was 100%. Six months after the treatment, excellent effect was obtained in 15 (60%) limbs and good effect was seen in 10 (40%) limbs. The total effective rate was 100%. Conclusion: DSA-guided foam sclerotherapy is a safe, effective and micro-invasive treatment for varicose veins of lower limbs with high technical success rate, although the long-term clinical effect needs to be further evaluated. (authors)

Precise orbit determination and point positioning using GPS, Glonass, Galileo and BeiDou

Directory of Open Access Journals (Sweden)

Tegedor J.

2014-04-01

Full Text Available State of the art Precise Point Positioning (PPP is currently based on dual-frequency processing of GPS and Glonass navigation systems. The International GNSS Service (IGS is routinely providing the most accurate orbit and clock products for these constellations, allowing point positioning at centimeter-level accuracy. At the same time, the GNSS landscape is evolving rapidly, with the deployment of new constellations, such as Galileo and BeiDou. The BeiDou constellation currently consists of 14 operational satellites, and the 4 Galileo In-Orbit Validation (IOV satellites are transmitting initial Galileo signals. This paper focuses on the integration of Galileo and BeiDou in PPP, together with GPS and Glonass. Satellite orbits and clocks for all constellations are generated using a network adjustment with observation data collected by the IGS Multi-GNSS Experiment (MGEX, as well as from Fugro proprietary reference station network. The orbit processing strategy is described, and orbit accuracy for Galileo and BeiDou is assessed via orbit overlaps, for different arc lengths. Kinematic post-processed multi-GNSS positioning results are presented. The benefits of multiconstellation PPP are discussed in terms of enhanced availability and positioning accuracy.

Follow-up of intracranial aneurysms treated with detachable coils: comparison of 3D inflow MRA at 3T and 1.5T and contrast-enhanced MRA at 3T with DSA

International Nuclear Information System (INIS)

Ramgren, Birgitta; Siemund, Roger; Cronqvist, Mats; Undren, Per; Holtaas, Stig; Nilsson, Ola G.; Larsson, Elna-Marie

2008-01-01

The purpose of this prospective study was to compare 3T and 1.5T magnetic resonance angiography (MRA) with digital subtraction angiography (DSA) for the follow-up of endovascular treated intracranial aneurysms to assess the grade of occlusion. Thirty-seven patients with 41 aneurysms who had undergone endovascular treatment with detachable coils were included. MRA was performed on the same day using an eight-channel sensitivity encoding head-coil with 3D axial inflow technique. At 3T, a contrast-enhanced transverse 3D fast gradient echo acquisition was also performed. Most patients underwent DSA the following day. MRA scans and DSA were classified first independently by two neuroradiologists and an interventional neuroradiologist. Secondly, a consensus was done. Source images, maximum intensity projection, multiplanar reconstruction and volume rendering reconstructions were used for MRA evaluations. A modification of the Raymond classification, previously used for DSA evaluation of recanalization, was used. Statistical comparison of the consensus showed that 3T MRA with 3D axial inflow technique had better agreement with DSA (κ = 0.43) than 1.5T MRA(κ = 0.21) and contrast-enhanced MRA (CE-MRA) at 3T (κ = 0.17). The susceptibility artefacts from the coil mesh were significally smaller at 3T (p = 0.002-0.007) than at 1.5T. 3T MRA, using a sensitivity encoding head-coil, showed better agreement with DSA than 1.5T and CE-MRA at 3T for evaluation of aneurysms treated with endovascular coiling. (orig.)

Four-dimensional CT angiography (4D-CTA) in the evaluation of juvenile nasopharyngeal angiofibromas: comparison with digital subtraction angiography (DSA) and surgical findings.

Science.gov (United States)

Xiao, Zebin; Zheng, Yingyan; Li, Jian; Chen, Dehua; Liu, Fang; Cao, Dairong

2017-12-01

To explore the value of four-dimensional CT angiography (4D-CTA) in the preoperative evaluation of juvenile nasopharyngeal angiofibromas (JNAs) using 320-row volume CT. 4D-CTA and DSA data of 18 patients with histopathologically proven JNAs were retrospectively reviewed. The location, extent, feeding vessels and stage of JNAs were assessed by two radiologists independently and blindly. The agreements between both reviewers and between 4D-CTA and surgical findings for assessing the above indicators were analysed, respectively. The radiation dose and the number of feeding arteries between 4D-CTA and digital subtraction angiography (DSA) were also compared. 4D-CTA showed high diagnostic consistency with surgical pathology for JNAs with consistent rates of 96.2 and 100% in both reviewers, respectively. The effective dose of 4D-CTA was significantly less than that of DSA (p 0.05). 4D-CTA can provide a reliable preoperative diagnosis and assessment of JNAs, which is useful for determining the surgical strategy and management of this condition.

Treatment of malignant biliary obstructions via the percutaneous approach; Interventionen bei malignen Gallenwegstenosen

Energy Technology Data Exchange (ETDEWEB)

Radeleff, B.A.; Lopez-Benitez, R.; Hallscheidt, P.; Grenacher, L.; Libicher, M.; Richter, G.M.; Kauffmann, G.W. [Radiologische Klinik der Ruprecht-Karls-Universitaet Heidelberg (Germany). Abteilung fuer Radiodiagnostik

2005-11-01

This paper gives an overview of experience and success of percutaneous transhepatic interventions in malignant biliary obstruction. Even after exhaustion of surgical and endoscopic therapy options, the percutaneously inserted stents provide effective palliation. The palliative treatment of malignant jaundice using a stent is an established procedure in clinical practice, particularly whenever the endoscopic, transpapillary approach is not possible due to high obstructions or previous surgery. The technical success rate is very high (about 95-100%), and the complication rate is about 10-30%. Since the patency rate of stents is higher than that of plastic endoprostheses, their primary use is justified despite higher costs, provided the patients are adequately selected. (orig.) [German] Vorgelegt wird eine Uebersicht ueber den gegenwaertigen Stellenwert radiologischer Interventionen bei malignen Gallenwegstenosen, die nur bei 10-20% der Patienten heilbar sind. Wenn ein endoskopisch transpapillaerer Zugang nicht moeglich ist, z. B. bei hohen Obstruktionen oder nach frueheren Eingriffen, ermoeglichen die perkutane transhepatische Punktion und Implantation von Metallendoprothesen eine gute Palliation. Die perkutane Gallengangdrainage und Stentplatzierung sind fuer den erfahrenen, interventionell taetigen Radiologen wenig kompliziert und mit einer Erfolgsrate von 95-100% dem endoskopischen Vorgehen deutlich ueberlegen. Morbiditaet und Mortalitaet der endoskopischen Verfahren waren in aelteren Arbeiten noch geringer als die der perkutanen Methoden. Aktuellen Studien zufolge sind beide Verfahren gleichwertig, wahrscheinlich aufgrund technischer Verbesserungen der perkutanen Interventionen. Die technische Erfolgsrate bei der Stentapplikation liegt ueber 95%. Mittels perkutaner transhepatischer biliaerer Drainageneinlage (PTCD) eingelegte Metallstents bleiben haeufiger und laenger offen als Plastikstents. Bei entsprechender Lebenserwartung des Patienten ist ihr Einsatz daher

Laterale 10-fach-Biopsie der Prostata liefert bei Karzinomverdacht überlegene Detektionsraten

Directory of Open Access Journals (Sweden)

von Knobloch R

2012-01-01

Full Text Available Einleitung:Die Sextantenbiopsie der Prostata ist für eine verlässliche Karzinomdiagnostik nicht ausreichend. Vielerorts werden bereits bei der Erstbiopsie 12 Stanzen entnommen. In einer großen Serie von 10-fach-Biopsien unter bilateraler lokaler Leitungsanästhesie, wie bereits 2002 publiziert [1], überprüften wir die Qualität unserer Technik als Standard für die Erstbiopsie. Methode:Zwischen April 2005 und Dezember 2007 führten wir bei 736 Männern (Durchschnittsalter 67,5 ± 8,39 Jahre die Erstbiopsie der Prostata durch. Indikation für die Biopsie war entweder ein erhöhter PSA-Wert oder ein auffälliger Tastbefund. Bei allen Männern erfolgte die Biopsie der Prostata unter bilateraler lokaler Leitungsanästhesie. Es wurden nur Proben aus der peripheren Zone der Prostata unter transrektaler Ultraschallkontrolle entnommen. Ergebnisse:Durch die Biopsie wurde in 372 von 736 Fällen (50,5 % ein Karzinom identifiziert. Die Karzinomdetektionsrate war proportional zum PSA-Wert und indirekt proportional zum Organvolumen. Es zeigte sich eine eindeutige Korrelation zwischen der Anzahl positiver Stanzen bei der Biopsie mit dem pathologischen Stadium des Prostatektomiepräparates. 12 Männer (1,6 % mussten wegen akuter Prostatitis und 5 (0,7 % wegen rektaler Blutung wieder ins Krankenhaus eingewiesen werden. Von den 182 Patienten des Untersuchers R. v. K. wurde der durchschnittliche Schmerz der Biopsie mit 1,69 von maximal 10 angegeben. Die Detektions- und Komplikationsraten dieser Biopsietechnik unterschieden sich nicht nach Durchführung von Assistenz- oder Fachärzten. Schlussfolgerung: Die präsentierte Biopsietechnik liefert mit nur 10 Stanzen eine überlegene Detektionsrate und eine geringe Rate an Komplikationen. Sie sollte als Basis für die Definition eines Standards für die Erstbiopsie der Prostata bei Karzinomverdacht dienen.

Kyphoplastie als palliative Therapieoption bei pathologischen Frakturen der Brust- und Lendenwirbelsäule

Directory of Open Access Journals (Sweden)

Hartwig E

2004-01-01

Full Text Available Bedingt durch Fortschritte in der Behandlung von Tumoren hat sich die Lebenserwartung von Krebspatienten deutlich verbessert. Jedoch steigt hiermit auch die Inzidenz von Knochenmetastasen. Mit wenigen Ausnahmen, die primären Knochentumoren betreffend, ist die Art der Behandlung dieser Läsionen in der Regel palliativ. Durch operatives Intervenieren muß bei diesen Patienten ein maximaler palliativer Effekt bei minimaler Morbidität und Mortalität erzielt werden. Die vorwiegenden Ziele sind Schmerzreduktion unter Erhalt der Stabilität und Funktion. Durch die Kyphoplastie wurden Zementierungsverfahren an der Wirbelsäule auch für pathologische Frakturen auf dem Boden metastatischer Manifestationen elegibel. In einer telefonischen Evaluation von 10 Patienten konnte die Wertigkeit des Verfahrens in der palliativen Situation bei Patienten mit Wirbelsäulenmetastasen gezeigt werden.

DSA lifetime measurements in 21Ne at high recoil velocity

International Nuclear Information System (INIS)

Grawe, H.; Heidinger, F.; Kaendler, K.

1977-01-01

States in 21 Ne up to 5 MeV excitation energy have been populated using the inverted reaction 2 H( 20 Ne,pγ). The Doppler shift attenuation (DSA) analysis of the pγ coincidence spectra taken in a Ge(Li) detector at 45 0 and 135 0 and an annular silicon surface barrier detector near 0 0 yielded the lifetimes of 8 states in 21 Ne. Due to the large recoil of vi/c approximately equal to 4% three new lifetimes were determined for the short lived levels at 2.80, 4.68 and 4.73 MeV, namely 10 +- 4 fs, 16 +- 4 fs and 10 +- 4 fs, respectively. The results are compared with rotational and shell model calculations. (orig.) [de

Endokrinologische Behandlung der Geschlechtsdysphorie bei Menschen mit Geschlechtsinkongruenz

Directory of Open Access Journals (Sweden)

Flütsch N

2015-01-01

Full Text Available Es gibt Menschen, die die innere Gewissheit besitzen, dass ihre Geschlechtsidentität nicht zu ihrem biologischen Ursprungsgeschlecht passt. Durch die Entwicklungen in der Medizin in den letzten hundert Jahren ist es möglich geworden, die körperlichen Geschlechtsmerkmale an das innerlich erlebte Geschlecht anzupassen. Die Zahl der Hilfesuchenden in den ärztlichen Ambulanzen und Privatpraxen hat in den vergangenen Jahren deutlich zugenommen. Das Vorgehen bei der Diagnostik und Therapieeinleitung erlebt zurzeit eine deutliche Veränderung hin zu mehr Patientenzentriertheit und Individualisierung des Transitionsprozesses. Dabei bildet die geschlechtsangleichende Hormontherapie ein wesentliches Standbein in der körperlichen Angleichung an das Gegengeschlecht. Unter Beachtung von bestimmten Sicherheitsaspekten ist eine Hormontherapie mit Sexualhormonen sicher und einfach durchzuführen. Regelmäßige Verlaufskontrollen sowie der offene und affirmative Umgang mit den Betroffenen tragen zudem wesentlich zur Sicherheit in der Behandlung bei.

Evaluation of a regional real-time precise positioning system based on GPS/BeiDou observations in Australia

Science.gov (United States)

Ding, Wenwu; Tan, Bingfeng; Chen, Yongchang; Teferle, Felix Norman; Yuan, Yunbin

2018-02-01

The performance of real-time (RT) precise positioning can be improved by utilizing observations from multiple Global Navigation Satellite Systems (GNSS) instead of one particular system. Since the end of 2012, BeiDou, independently established by China, began to provide operational services for users in the Asia-Pacific regions. In this study, a regional RT precise positioning system is developed to evaluate the performance of GPS/BeiDou observations in Australia in providing high precision positioning services for users. Fixing three hourly updated satellite orbits, RT correction messages are generated and broadcasted by processing RT observation/navigation data streams from the national network of GNSS Continuously Operating Reference Stations in Australia (AUSCORS) at the server side. At the user side, RT PPP is realized by processing RT data streams and the RT correction messages received. RT clock offsets, for which the accuracy reached 0.07 and 0.28 ns for GPS and BeiDou, respectively, can be determined. Based on these corrections, an accuracy of 12.2, 30.0 and 45.6 cm in the North, East and Up directions was achieved for the BeiDou-only solution after 30 min while the GPS-only solution reached 5.1, 15.3 and 15.5 cm for the same components at the same time. A further improvement of 43.7, 36.9 and 45.0 percent in the three directions, respectively, was achieved for the combined GPS/BeiDou solution. After the initialization process, the North, East and Up positioning accuracies were 5.2, 8.1 and 17.8 cm, respectively, for the BeiDou-only solution, while 1.5, 3.0, and 4.7 cm for the GPS-only solution. However, we only noticed a 20.9% improvement in the East direction was obtained for the GPS/BeiDou solution, while no improvements in the other directions were detected. It is expected that such improvements may become bigger with the increasing accuracy of the BeiDou-only solution.

Shoulder injuries in overhead sports; Schultergelenkverletzungen bei Ueberkopfsportarten

Energy Technology Data Exchange (ETDEWEB)

Woertler, K. [Technische Universitaet Muenchen (Germany). Institut fuer Roentgendiagnostik

2010-05-15

Overhead sport places great demands on the shoulder joint. Shoulder pain in overhead athletes and throwers can in the majority of cases be attributed to lesions resulting from chronic overuse of tendons and capsuloligamentous structures or to sequels of microinstability and secondary impingement. Due to its great impact on therapeutic decisions, imaging in athletes with unclear shoulder pain is a challenge. In this connection, magnetic resonance (MR) arthrography represents the cross-sectional imaging modality of first choice, as it allows depiction and exclusion of pathologic alterations of all relevant joint structures with sufficient confidence. This article reviews the biomechanical and clinical aspects and MR arthrographic features of the most common shoulder pathologies in overhead athletes, including biceps tendinopathy, superior labral anterior-posterior (SLAP) lesions, rotator cuff lesions, as well as extrinsic and intrinsic impingement syndromes. (orig.) [German] Ueberkopfsportarten stellen grosse Anforderungen an das Schultergelenk. Schulterbeschwerden bei Ueberkopf- und Wurfsportlern koennen in der Mehrzahl der Faelle auf eine chronische Ueberlastung von Sehnen und Kapsel-Band-Strukturen oder auf die Folgen einer Mikroinstabilitaet und sekundaerer Impingementsyndrome zurueckgefuehrt werden. Wegen ihres grossen Einflusses auf die Therapieentscheidung stellt die Bildgebung bei Athleten mit unklaren Schulterbeschwerden eine Herausforderung dar. Die MR-Arthrographie ist in diesem Zusammenhang als Schnittbildverfahren der ersten Wahl anzusehen, da sie den Nachweis bzw. Ausschluss pathologischer Veraenderungen aller relevanten Gelenkstrukturen mit ausreichender Sicherheit ermoeglicht. Dieser Artikel gibt eine Uebersicht ueber biomechanische und klinische Aspekte sowie MR-arthrographische Befunde der haeufigsten Schultergelenkpathologien bei Ueberkopfsportlern, wie Bizepstendinopathie, Superior-labral-anterior-posterior- (SLAP-)Laesionen, Laesionen der

Working memory in volunteers and schizophrenics using BOLD fMRI; Das Arbeitsgedaechtnis bei Gesunden und bei Schizophrenen: Untersuchungen mit BOLD-fMRT

Energy Technology Data Exchange (ETDEWEB)

Giesel, F.L. [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg, Abteilung Radiologie (Germany); Deutsches Krebsforschungszentrum (DKFZ), Abteilung Radiologie, Heidelberg (Germany); Hohmann, N. [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg, Abteilung Radiologie (Germany); Psychiatrische Universitaetsklinik Heidelberg, Sektion Gerontopsychiatrie (Germany); Seidl, U.; Kress, K.R.; Schoenknecht, P.; Schroeder, J. [Psychiatrische Universitaetsklinik Heidelberg, Sektion Gerontopsychiatrie (Germany); Kauczor, H.-U.; Essig, M. [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg, Abteilung Radiologie (Germany)

2005-02-01

Functional magnetic resonance imaging uses the blood oxygen level-dependent effect (BOLD MRI) for noninvasive display of cerebral correlatives of cognitive function. The importance for the understanding of physiological and pathological processes is demonstrated by investigations of working memory in schizophrenics and healthy controls. Working memory is involved in processing rather than storage of information and therefore is linked to complex processes such as learning and problem solving. In schizophrenic psychosis, these functions are clearly restricted. Training effects in the working memory task follow an inverse U-shape function, suggesting that cerebral activation reaches a peak before economics of the brain find a more efficient method and activation decreases. (orig.) [German] Die funktionelle Magnetresonanztomographie (fMRT) nutzt den ''blood oxygen level dependent effect'' (BOLD-Effekt) zur nichtinvasiven Darstellung zerebraler Korrelate kognitiver Funktionen. Die Bedeutung dieses Verfahrens fuer das Verstaendnis physiologischer und pathologischer Prozesse wird anhand von Untersuchungen zum Arbeitsgedaechtnis bei Schizophrenen und gesunden Kontrollpersonen verdeutlicht. Das Arbeitsgedaechtnis dient weniger der Speicherung, sondern vielmehr der Verarbeitung von Informationen und ist deshalb in komplexe Prozesse wie Lernen und Problemloesen eingebunden. Im Rahmen schizophrener Psychosen kommt es zu einer deutlichen Einschraenkung dieser Funktionen. Erwartungsgemaess zeigen sich unter Durchfuehrung eines Arbeitsgedaechtnisparadigmas Unterschiede in der zerebralen Aktivitaet, die jedoch bei den Erkrankten unter Therapie prinzipiell reversibel sind. Von Interesse sind auch Trainingseffekte bei Gesunden, wobei eine verminderte Aktivierung nach Training auf eine ''Oekonomisierung'' schliessen laesst. (orig.)

Tryptophanabhängige Synthese von indolhaltigen Pigmenten bei verschiedenen humanpathogenen Asco- und Basidiomyceten

OpenAIRE

Nies, Silke Marie

2006-01-01

Der Begriff "Pigment" beschreibt in erster Linie farbige Substanzen. Pigmente sind aber darüber hinaus für wichtige metabolische oder physiologische Prozesse verantwortlich. Im Reich der Pilze gibt es eine Vielzahl von Pigmenten. Zu ihnen zählen die Melanine, die Carotenoide, die Naphthoquinone, die Phenoxazine, die Flavonoide sowie indolhaltige Pigmente. Gewisse Indolderivate wurden von einer Arbeitsgruppe um Prof. Mayser 1998 erstmals bei der Hefe Malassezia furfur beschrieben, bei der ...

Optimal space-energy splitting in MCNP with the DSA

International Nuclear Information System (INIS)

Dubi, A.; Gurvitz, N.

1990-01-01

The Direct Statistical Approach (DSA) particle transport theory is based on the possibility of obtaining exact explicit expressions for the dependence of the second moment and calculation time on the splitting parameters. This allows the automatic optimization of the splitting parameters by ''learning'' the bulk parameters from which the problem dependent coefficients of the quality function (second moment time) are constructed. The above procedure was exploited to implement an automatic optimization of the splitting parameters in the Monte Carlo Neutron Photon (MCNP) code. This was done in a number of steps. In the first instance, only spatial surface splitting was considered. In this step, the major obstacle has been the truncation of an infinite series of ''products'' of ''surface path's'' leading from the source to the detector. Encouraging results from the first phase led to the inclusion of full space/energy phase space splitting. (author)

Potenzielle Arzneimittelwechsel-wirkungen und unerwünschte Arzneimittelwirkungen bei stationären dermatologischen Patienten.

Science.gov (United States)

Koch, Lukas; Kränke, Birger; Aberer, Werner

2016-11-01

Informationen zur Häufigkeit von Arzneimittelwechselwirkungen und unerwünschten Arzneimittelwirkungen zu präsentieren und Hilfestellung zu leisten, wie diese wichtigen Probleme in der pharmakologischen Behandlung stationärer dermatologischer Patienten minimiert werden können. Die Medikation von 1 099 stationären dermatologischen Patienten wurde retrospektiv mittels einer Internet-basierten Software für Medikamenteninteraktionen (Diagnosia ® Check) auf Arzneimittelwechselwirkungen und unerwünschte Arzneimittelwirkungen analysiert. Wir beschreiben eine Gesamthäufigkeit relevanter Arzneimittelwechselwirkungen von 51,7 % mit durchschnittlich 3,2 Interaktionen pro betroffenem stationären Patienten. Arzneimittelkombinationen, die gemieden werden sollten, wurden bei 5,7 % der Studienpopulation festgestellt. Der wichtigste Risikofaktor war die Gesamtzahl der verabreichten Medikamente. Die Arzneimittelgruppen, die bei der Mehrzahl der Wechselwirkungen beteiligt waren, waren Analgetika, Herz-Kreislauf-Medikamente und gerinnungshemmende Medikamente sowie Antidepressiva. Das Risiko unerwünschte Arzneimittelwirkungen auszubilden wurde bei 53,1 % der stationären Patienten als "hoch" eingestuft. Die fünf wichtigsten unerwünschten Nebenwirkungen in dieser Patientengruppe waren Blutungen, Obstipation, anticholinerge Effekte, Sedierung und orthostatische Effekte. Potenzielle Arzneimittelwechselwirkungen sowie unerwünschte Arzneimittelwirkungen sind bei stationären dermatologischen Patienten alarmierend häufig. Bei jedem zweiten Patienten besteht die Gefahr, derartige Wechselwirkungen oder unerwünschte Nebenwirkungen zu erleiden und jeder zwanzigste Patient erhält eine Arzneimittelkombination, die nicht verabreicht werden sollte. Erhöhte Wachsamkeit ist erforderlich, um die gefährdeten Patienten zu erkennen. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Spinal metastases of malignant gliomas; Spinale Metastasierung bei malignen Gliomen. Zwei Fallbeschreibungen

Energy Technology Data Exchange (ETDEWEB)

Materlik, B; Steidle-Katic, U; Feyerabend, T; Richter, E [Medizinische Univ. Luebeck (Germany). Klinik fuer Strahlentherapie und Nuklearmedizin; Wauschkuhn, B [Medizinische Univ. Luebeck (Germany). Klinik fuer Neurologie

1998-09-01

Purpose: Extracranial metastases of malignant gliomas are rare. We report 2 cases with spinal metastases in patients suffering from glioma. Patients and Method: Two patients (33 and 57 years old) developed spinal canal metastases of a glioblastoma multiforme and anaplastic astrocytoma Grade III respectively 25 and 9 months after surgical resection and radiotherapy. Both metastases were confirmed pathohistologically. Results: Intraspinal metastases were irradiated with a total dose of 12.6 Gy and 50 Gy. Treatment withdrawal was necessary in one patient due to reduced clinical condition. Regression of neurological symptoms was observed in the second patient. Conclusions: Spinal spread of malignant glioma should be considered during care and follow-up in glioma patients with spinal symptoms. (orig.) [Deutsch] Hintergrund: Maligne Gliome metastasieren aeusserst selten extrakraniell. Wir stellen zwei Faelle einer spinalen Filialisierung bei Gliompatienten vor. Patientengut und Methode: Zwei Patienten (33 und 57 Jahre alt) entwickelten 25 bzw. neun Monate nach Resektion und postoperativer Radiatio eines Glioblastoma multiforme und eines anaplastischen Astrozytoms WHO-Grad III histologisch gesicherte intraspinale Metastasen, welche durch Sensibilitaetsstoerungen der Beine symptomatisch wurden. Ergebnisse: Die intraspinalen Filiae wurden mit 12,6 Gy bzw. 50 Gy bestrahlt. Bei einem Patienten musste die Radiatio wegen zunehmender Verschlechterung des Allgemeinzustandes abgebrochen werden, bei dem zweiten Patienten besserte sich die neurologische Symptomatik. Schlussfolgerung: Bei der Betreuung von Gliompatienten sollte, insbesondere in der Nachsorge, an die Moeglichkeit der spinalen Metastasierung mit entsprechender Symptomatik gedacht werden. (orig.)

Pulmonary manifestations in collagen vascular diseases; Pulmonale Manifestationen bei Kollagenosen

Energy Technology Data Exchange (ETDEWEB)

Vogel, M.N.A. [Thoraxklinik, Universitaetsklinikum Heidelberg, Abteilung fuer Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Heidelberg (Germany); Universitaetsklinikum Heidelberg, Translational Lung Research Center (TLRC), Heidelberg (Germany); Kreuter, M. [Thoraxklinik, Universitaetsklinikum Heidelberg, Zentrum fuer interstitielle und seltene Lungenerkrankungen, Pneumologie und Beatmungsmedizin, Heidelberg (Germany); Universitaetsklinikum Heidelberg, Translational Lung Research Center (TLRC), Heidelberg (Germany); Kauczor, H.U. [Radiologische Klinik, Universitaetsklinikum Heidelberg, Abteilung fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Universitaetsklinikum Heidelberg, Translational Lung Research Center (TLRC), Heidelberg (Germany); Heussel, C.P. [Thoraxklinik, Universitaetsklinikum Heidelberg, Abteilung fuer Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Heidelberg (Germany); Radiologische Klinik, Universitaetsklinikum Heidelberg, Abteilung fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Universitaetsklinikum Heidelberg, Translational Lung Research Center (TLRC), Heidelberg (Germany)

2016-10-15

Pulmonary complications are frequent in patients with collagen vascular diseases (CVD). Frequent causes are a direct manifestation of the underlying disease, side effects of specific medications and lung infections. The standard radiological procedure for the work-up of pulmonary pathologies in patients with CVD is multidetector computed tomography (MDCT) with thin-slice high-resolution reconstruction. The accuracy of thin-slice CT for the identification of particular disease patterns is very high. The pattern of usual interstitial pneumonia (UIP) representing the direct pulmonary manifestation of rheumatoid arthritis (RA) can be identified with a sensitivity of 45 % and a specificity of 96 %. Both direct pulmonary manifestations, drug-induced toxicity and certain infections can have a similar appearance in thin-slice MDCT in various forms of CVD. Knowledge of the patterns and causes contributes to the diagnostic certainty. At first diagnosis of a CVD and associated pulmonary symptoms thin-slice MDCT is recommended. Clinical, lung function and imaging follow-up examinations should be performed every 6-12 months depending on the results of the MDCT. In every case the individual CT morphological patterns of pulmonary involvement must be identified. The combination of information on the anamnesis, clinical and imaging results is a prerequisite for an appropriate disease management. (orig.) [German] Pulmonale Komplikationen sind bei Patienten mit Kollagenosen keine Seltenheit. Haeufig sind eine direkte Manifestation der Grunderkrankung, eine Nebenwirkung der medikamentoesen Therapie oder eine Lungeninfektion die Ursachen. Das radiologische Standardverfahren zur Klaerung pulmonaler Pathologien bei Patienten mit Kollagenosen ist die Multidetektorcomputertomographie mit duennschichtigen Rekonstruktionen (Duennschicht-MDCT). Die Treffsicherheit der Duennschicht-MDCT ist fuer die Identifikation eines Erkrankungsmusters sehr hoch. So kann beispielsweise das Muster einer

Die Rolle von Osteoklasten bei der arthritischen Knochenerosion

Directory of Open Access Journals (Sweden)

Schett G

2003-01-01

Full Text Available Knöcherne Erosionen stellen eine wesentliche Ursache für die funktionelle Einschränkung von Patienten mit rheumatoider Arthritis dar. Bis vor kurzem war über den Pathomechanismus dieser Veränderungen nur wenig bekannt. Dieser Review faßt die letzten Erkenntnisse über die Ausbildung einer Knochenschädigung bei entzündlichen Gelenkerkrankungen zusammen und fokussiert insbesondere die Rolle von Osteoklasten. Es wird ein Überblickzu den Hinweisen für eine Präsenz von Osteoklasten im entzündlich veränderten Gelenk gegeben. Weiters werden die Faktoren diskutiert, die die Osteoklastogenese im Rahmen einer Gelenkentzündung aktivieren können. Hier wird im besonderen auf die Rolle von Receptor-Activator of Nuclear Factor Kappa B Ligand (RANKL eingegangen. Im weiteren werden die Auswirkungen einer Osteoklastenhemmung in den verschiedenen Arthritismodellen zusammengefaßt und Möglichkeiten einer therapeutischen Nutzung bei rheumatoider Arthritis diskutiert.

Strahlungsfeldbedingungen bei der Ionisationsdosimetrie

Science.gov (United States)

Krieger, Hanno

Bei der Dosimetrie von Photonenstrahlungen mit luftgefüllten Ionisationskammern werden in diesem Kapitel zwei Grenzfälle unterschieden. Der eine Fall ist die Bedingung des so genannten Sekundärelektronengleichwichts im Kammervolumen. In diesem Fall bestimmen ausschließlich die Photonen im Messvolumen die dosimetrische Anzeige. Der zweite Grenzfall ist gegeben, wenn das Luftvolumen und die Kammer das Strahlungsfeld im Phantom so wenig stören, dass der Sekundärelektronenfluss unverändert bleibt. Diese Bedingungen nennt man BRAGG-GRAY-Bedingungen. Beide Grenzfälle sind in der Praxis nur näherungsweise zu verwirklichen. Abweichungen müssen durch entsprechende Korrekturen oder Kalibrierungen berücksichtigt werden.

Neuere Untersuchungen zur Prädiktion von EEG-Signalen bei Epilepsie

Directory of Open Access Journals (Sweden)

C. Niederhöfer

2007-06-01

Full Text Available Seit einigen Jahren ist die Analyse von EEG-Signalen bei Epilepsie Gegenstand zahlreicher wissenschaftlicher Arbeiten; Zielvorstellung ist dabei die Entwicklung von Verfahren zur Erkennung eines möglichen Voranfallszustandes. Im Vordergrund steht beispielsweise die Approximation einer so genannten effektiven Korrelationsdimension, die Bestimmung der maximalen Lyapunov-Exponenten, Detektionsverfahren für Muster bei Zellularen Nichtlinearen Netzwerken, die Bestimmung der mittleren Phasenkohärenz und Verfahren zur nichtlinearen Prädiktion von EEG-Signalen. Trotz umfangreicher Bemühungen kann bis heute eine Erkennung von Anfallsvorboten mit einer Sensitivität und Spezifität, die eine automatisierte Anfallsvorhersage ermöglichen würde, noch nicht durchgeführt werden. In diesem Beitrag werden neue Ergebnisse zur Prädiktion von EEG-Signalen bei Epilepsie vorgestellt. Dabei werden Signale, welche mittels intrakranieller electrocorticographischer (ECoG und stereoelectroencephalographischer (SEEG Ableitungen registriert wurden, segmentweise analysiert. Unter der Annahme, dass sich Änderungen des Systems ,,Gehirn" als Änderungen im Prädiktor, d.h. in seinen Systemparametern widerspiegeln, könnte eine nähere Betrachtung der Prädiktoreigenschaften zu einer Erkennung von Anfallsvorboten führen.

Pitfalls in magnetic resonance imaging of the hip; ``Pitfalls`` in der Kernspintomographie der Hueftgelenke

Energy Technology Data Exchange (ETDEWEB)

Schedel, H [Strahlenklinik und Poliklinik, Universtaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Wicht, L [Strahlenklinik und Poliklinik, Universtaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Kern, A [Strahlenklinik und Poliklinik, Universtaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Vogl, T [Strahlenklinik und Poliklinik, Universtaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Felix, R [Strahlenklinik und Poliklinik, Universtaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany)

1994-12-31

In the differential diagnosis of unspecific hip pain MRI becomes increasing importance. In particular it is useful in the diagnosis of avascular necrosis, primary and secondary bone tumors, osteomyelitis and synovial processes. According to the higher frequence of MR-examinations of the hip the number of nonpathological incidental findings rises. These `pitfalls` which were found in MRI of 152 patients with unspecific hip pain are demonstrated. Soft tissue penetrating cortical lesions of the femoral neck (herniation pit), physiological changes of bone marrow, synovial proliferation of the hip capsule, epiphyseal scares of the femoral head and the transient osteoporosis are some of the morphological changes of the hip, which may cause difficulties and misinterpretations in MRI of the hip. The knowledge of their radiological characteristics in MRI is important, especially in cases of unspecific hip pain. (orig.) [Deutsch] Die Magnetresonanztomographie gewinnt bei der Differentialdiagnose unspezifischer Hueftbeschwerden zunehmend an Bedeutung. Vor allem die avaskulaere Hueftkopfnekrose, primaere und sekundaere Knochentumoren, Osteomyelitis und synoviale Prozesse lassen sich kernspintomographisch gut differenzieren. Durch den haeufigeren Einsatz der Kernspintomographie im Hueftbereich werden aber auch vermehrt morphologische Veraenderungen nichtpathologischer Genese gefunden, die als physiologische Normvarianten bzw. benigne Veraenderungen von pathologischen Befunden abzugrenzen sind. In dieser Arbeit werden die bei der kernspintomographischen Untersuchung von 152 Patienten mit unklaren Hueftschmerzen gefundenen `pitfalls` vorgestellt. Durch kortikale Defekte des Schenkelhalses penetrierendes Weichteilgewebe (herniation pit), physiologische Knochenmarksveraenderungen der Acetabulum- und Femurregion, synoviale Proliferationen der Hueftgelenkskapsel, epiphysaere Narben des Femurkopfes und die transitorische Osteoporose sind einige der morphologischen Veraenderungen im

Studies on blood supply of liver metastasis with DSA, CT and portal vein perfusion CT during superior mesenteric arterial portography

International Nuclear Information System (INIS)

Li Zhigang; Shi Gaofeng; Huang Jingxiang; Li Shunzong; Liang Guoqing; Wang Hongguang; Han Pengyin; Wang Qi; Gu Tieshu

2008-01-01

Objective: To probe the blood supply of liver metastasis by celiac artery, proper hepatic artery DSA, portal vein perfusion CT during superior mesenteric arterial portography (PCTAP). Methods: One hundred patients with liver metastases were examined prospectively by plain CT scan, multiphase enhanced CT scan, celiac arteriography and proper hepatic arteriography. Of them, 56 patients were examined by PCTAP. All primary lesions were confirmed by operation and (or) pathology examination. In order to investigate the blood supply of metastasis lesions, the software of Photoshop was used to obtain the time-attenuation curves (TDC) of tumor center, tumor edge, portal vein and normal liver parenchyma adjacent to the tumor to calculate liver perfusion for DSA image analysis, while a deconvolution model from CT perfusion software was designed for the dual blood supply. Results: DSA findings: TDC of proper hepatic arteriography showed: the mean peak concentration (K value) in tumor centers was (67 ± 12)%, and it was (76 ± 15)% for peritumor tissue, (51 ± 10)% in normal liver parenchyma. TDC of celiac arteriogaphy showed that the contrast concentration of tumor centers and tumor edge increased fast in early stage, then maintained a slight upward plateau, in the meanwhile, the contrast concentration of normal liver parenchyma kept increasing slowly. PCTAP findings: tumors exhibited no enhancement during 30 s continued scans. Conclusion: The blood supply of liver metastasis mainly comes from hepatic artery, but barely from portal vein. (authors)

Anwendung der extrakorporalen Stoßwellentherapie bei kalzifizierender Periathropathia humeroscapularis, Fersensporn und Epicondylitis humeri - Erfahrungsbericht aus dem Wilhelminenspital

Directory of Open Access Journals (Sweden)

Feyertag J

2004-01-01

Full Text Available Die Stoßwellentherapie wird bei verschiedenen Indikationen, die unter konservativen Therapien schwer zu schwer zu behandeln sind, eingesetzt. Dazu zählen die kalzifizierenden Schultererkrankungen (Tendinitis calcarea, Epicondylitis humeri (EHR und die plantare Fasciitis mit/ohne plantarem Fersensporn (FSP. Berichtet werden die Ergebnisse von 147 Patienten (102 Frauen/45 Männer, mittleres Alter betrug 57,8 Jahre, die mittels einer einmaligen extrakorporalen Stoßwellentherapie (ESWT (Tend. calc. 82 %, FSP 11 % oder EHR 7 % mittels eines HMT-ReflecTron therapiert wurden. Verabreicht wurden im Mittel 1.800 Stoßwellen. Untersucht wurde die subjektive Verbesserung der Schmerzen anhand einer visuellen Analogskala vor und 6 Wochen nach der Therapie bei allen Patienten. Bei Patienten mit Tendinitis calcarea wurde auch eine Verbesserung der Funktion sowie Veränderungen der Kalzifizierungen untersucht. Bei allen Patienten konnte eine statistisch signifikante Verbesserung der Schmerzen sowie des Bewegungsumfanges beobachtet werden (p 0,0001. Röntgenaufnahmen ergaben eine partielle Verkleinerung der Kalkdepots bei ca. 80 % der Patienten. Aufgrund der geringen Zahl der Patienten fand sich für die EHR keine signifikante Verbesserung der Schmerzsymptomatik. Eine einmalige ESWT kann zu einer deutlichen Verbesserung der Schmerzsymptomatik und zu einer Verbesserung des Bewegungsumfanges führen. Bei 80 % der Patienten mit einer Tendinitis calcarea findet sich weiter eine partielle Verkleinerung der Kalkdepots 6 Wochen nach Therapie.

The value of MR angiography in the diagnosis of deep vein thrombosis of the lower limbs: comparative study with DSA

International Nuclear Information System (INIS)

Feng Min; Wang Shuzhi; Gu Jianping; Sun Jun; Mao Cunnan; Lu Lingquan; Yin Xindao

2007-01-01

Objective: To assess the clinical values of MR angiography (MRA) in the detection of deep vein thrombosis of the lower limbs. Methods: Two-dimensional time of flight (2D TOF) MRA was performed in thirty patients who were suspected of having deep vein thrombosis in the lower limbs. The findings of MRA were compared to that of digital subtraction angiography (DSA). Results: twenty-five cases showed deep vein thrombosis in the lower limbs, the MRA findings included venous filling defect (14 cases), occlusions and interruptions of veins (8 cases), venous recanalizations (3 cases), collateral veins (25 cases). Taking the results of DSA as a golden standard, MRA detected all of the affected cases with only one case as the false positive. Conclusion: 2D TOF MRA is a method of choice in the diagnosis of deep vein thrombosis of the lower limbs. (authors)

Neuroimaging of cerebral vasculitis; Bildgebung zerebraler Vaskulitiden

Energy Technology Data Exchange (ETDEWEB)

Wengenroth, M. [Universitaetsklinikum Schleswig-Holstein, Campus Luebeck, Institut fuer Neuroradiologie, Luebeck (Germany); Klinikum der Ludwig-Maximilians-Universitaet, Institut fuer klinische Radiologie, Muenchen (Germany); Saam, T. [Klinikum der Ludwig-Maximilians-Universitaet, Institut fuer klinische Radiologie, Muenchen (Germany); Haehnel, S. [Universitaetsklinikum Heidelberg, Abteilung Neuroradiologie, Heidelberg (Germany)

2016-01-15

Cerebral vasculitis can have a variety of origins. Furthermore, there are no vasculitis-specific symptoms or imaging signs and vasculitis of the CNS can mimic many other neurological diseases, which require different treatment approaches. Thus, the clinical and radiological diagnosis of cerebral vasculitis is challenging. Magnetic resonance imaging (MRI) and MR angiography (MRA) should be the radiological imaging methods of choice to assess the degree of parenchymal damage and to detect vessel wall changes. If the results are unclear digital subtraction angiography (DSA) should be pursued in order to also detect changes in medium sized vessels. Vasculitis of small vessels cannot be detected by vascular imaging and requires brain or leptomeningeal biopsy. In this review we present the current diagnostic approach and a variety of imaging findings in cerebral vasculitis and discuss the main radiological differential diagnoses. (orig.) [German] Die zerebrale Vaskulitis kann viele Ursachen haben. Daher ist die klinische und radiologische Diagnose schwierig, auch weil es etliche vaskulitistypische Symptome und MR-Befunde bei anderen Erkrankungen gibt. Die ZNS-Vaskulitis kann zahlreiche andere neurologische Erkrankungen imitieren, die unterschiedlicher Therapie beduerfen. MRT und MR-Angiographie (MRA) sind die Verfahren der Wahl, mit denen die radiologische Diagnostik begonnen werden sollte, um den Parenchymschaden und den Gefaessbefall zu beurteilen. Bei unklaren Befunden kann eine digitale Subtraktionsangiographie (DSA) ergaenzt werden, um auch mittelgrosse Gefaesse beurteilen zu koennen. Der Befall kleiner Gefaesse kann nur bioptisch nachgewiesen werden. In der folgenden Uebersicht stellen wir das diagnostische Herangehen bei zerebraler Vaskulitis vor, praesentieren zahlreiche Befunde und diskutieren die wichtigsten radiologischen Differenzialdiagnosen. (orig.)

Magnetic resonance tomography in eclampsia; Magetresonanztomographie bei Eklampsie

Energy Technology Data Exchange (ETDEWEB)

Uhlig, U. [St.-Vincentius-Krankenhaeuser, Karlsruhe (Germany). Radiologische Klinik

1995-05-01

Eclampsia is a rare but severe complication during the course of a pregnancy. The CT-findings at the brain are well known. Reports on MRT-findings are limited, however, especially in German literature. We describe the MRT picture of the cerebral changes caused by eclampsia and discuss the advantages of MRT in comparison with CT. The use of contrast agents with MRT shows breakdown of blood-brain barrier but does not provide any information of therapeutical consequences and should be avoided during pregnancy. An early and targeted use of MRT in any case of unclear or suspicious neurological symptoms during pregnancy is recommended. MRT supports differential diagnosis regarding non pregnancy-related cerebral disease and can be helpful for therapy planning in cases of preeclampsia. Additionally, MRT offers the possibility to control the effect of therapy with regard to brain damage. (orig.) [Deutsch] Die Eklampsie ist eine seltene aber erhebliche Komplikation im Verlauf einer Schwangerschaft. Die computertomographischen Veraenderungen im Gehirn sind bekannt. Mitteilungen von kernspintomographischen Befunden finden sich vor allem in der deutschen Literatur noch selten. Wir beschreiben das kernspintomographische Bild der zerebralen Veraenderungen bei Eklampsie und diskutieren die Vorteile der MRT im Vergleich zur CT. Die Gabe von Kontrastmittel bei der MRT weist zwar die Blut-Hirn-Schrankenstoerung nach, bringt aber keine therapeutisch relevanten Informationen. Sie sollte waehrend der Schwangerschaft vermieden werden. Ein frueher und gezielter Einsatz der MRT bei unklaren oder verdaechtigen neurologischen Symptomen waehrend der Schwangerschaft ist sinnvoll. Die MRT unterstuetzt die Differentialdiagnose in bezug auf nicht schwangerschaftsbezogene zerebrale Leiden und kann fuer die Therapie richtungweisend sein, wenn die Gestose noch nicht ausgepraegt ist. (orig.)

PENGARUH CORPORATE GOVERNANCE TERHADAP TAX AVOIDANCE (Perusahaan Pertambangan yang terdaftar di BEI

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Sri Mulyani

2018-05-01

Full Text Available he purpose of this research is to know the influence of institutional ownership, independent commissioner, audit committee and audit quality to tax avoidance at mining company listed on BEI year 2014-2016. The population of this study is mining companies listed on the BEI 2014-2016 as many as 46 companies. Sampling used in this research purposive sampling method. Data source is secondary data obtained from company website and BEI website (www.idx.co.id. This study uses multiple regression analysis to analyze data with the help of SPSS 21 edition program. The results of this study indicate that the variables of institutional ownership, audit committee and audit quality have significant influence on tax avoidance, while independent commissioner variable has no significant effect on tax avoidance. The results of this study are expected to be an additional consideration of the management in conducting tax avoidance is correct and efficient without violating applicable tax laws, and can provide additional information for users of financial statements in investment decision making.

Intravenous DSA as a screening method for cerebral aneurysms

International Nuclear Information System (INIS)

Fukaya, Hiroyuki; Sunami, Kaneo; Hoshi, Seiichiro; Komiya, Hirokazu; Saeki, Naokatsu.

1990-01-01

Intravenous DSA (IVDSA) was evaluated as a screening method for cerebral aneurysms. It was performed 390 times in 372 cases. Clinically useful images were obtained in 94.1% in all examinations. Nineteen aneurysms were visualized in cerebral angiography among 21 cases with SAH or 3rd nerve palsy, whereas in IVDSA 15 aneurysms were noted. Aneurysms not visualized in IVDSA were all 4 mm or less in size. Therefore, aneurysms, more than 4 mm in size, which have higher risks for rupture, were detectable in IVDSA. Based on these findings, IVDSA is considered to be clinically useful in screening for aneurysms. In all 372 cases, 33 aneurysms were suspected in IVDSA findings, whereas in cerebral angiography 21 of them turned to be aneurysms. Such 12 false positive cases were distributed mainly at anterior communicating and middle cerebral arteries. Improvement of image resolution, avoidance of vessel overlapping and proper selection of screened cases should be investigated for further development of this screening method. (author)

Nuclear lifetime measurements with the DSA coincidence method in inverse reactions

International Nuclear Information System (INIS)

Hermans, J.A.J.

1977-01-01

This thesis describes lifetime measurements with the DSA coincidence method in inverse reactions. Bombardment of 2 H and 3 H targets with heavy ions of energies up to 50 MeV produces nuclei recoiling at initial velocities of v(0) approximately equal to 0.05 c. Heavy-ion beams of 11 B, 12 C, 14 N, 16 O, 18 O, 19 F, 27 A1, 28 Si, 30 Si, 31 P, 32 S, 35 Cl and 37 Cl are at present available from the Utrecht 6 MV EN tandem accelerator. The recoil nuclei are slowed down in Mg, Al, Cu, Ag or Au and the γ-ray Doppler pattern is observed with a large Ge(Li) detector in coincidence with protons

Comparison between fast contrast-enhanced MR angiography and DSA in diagnosing spinal cord vascular malformations

International Nuclear Information System (INIS)

Wang Wu; Li Minghua; Fang Chun; Wang Jue; Xiao Yunfeng

2007-01-01

Objective: To evaluate the diagnostic and clinical value of fast contrast-enhanced MR angiography (CE-MRA) with elliptic centric phase-encoding in spinal cord vascular malformations. Methods Fast three-dimensional contrast-enhanced MR angiography with elliptic centric phase-encoding and superconducting 1.5T system was applied prospectively in twenty-five consecutive patients with clinically suspected of spinal cord vascular malformations. All cases were performed with selective spinal digital subtraction angiography, including 18 cases treated by surgery and 2 of them with embolization before surgery, MR angiography follow up were undertaken in ten patients after surgery. Comparing fast contrast-enhanced MR angiography with DSA in diagnosing spinal cord vascular malformations included the origin of feeding artery, the feeding artery, the fistula or the nidus, the draining vein, and the vessel image quality based on the gold standard of selective spinal digital subtraction angiography. Results: Surgically proven diseases included spinal arteriovenous malformations(3 cases), spinal cord perimedullary arteriovenous fistulas (5 cases), spinal dural arteriovenous fistulas (8 cases), paravertebral arteriovenous fistulas (1 case), and spontaneous spinal epidural hematomas (2 eases). Comparing with DSA, the accuracy of MR angiography in diagnosing spinal cord vascular malformations; and detecting the origin of the feeding artery, the feeding artery, the shunt or the nidus and the draining vein were 93.8%, 92%, 96.2%, 100% and 100%, respectively. Overall the degree vascular enhencement were judged to be similar(P>0.05), but the vessel continuity of MRA was inferior to DSA (P<0.05). However, 9 cases of MRA showed no abnormal vascular malformation coinciding with those of surgery. Posttreatment MR angiography did not depict any abnormal vessels again. Conclusions: Fast three-dimensional contrast-enhanced MR angiography with elliptic centric phase-encoding may provide

Einflussfaktoren auf den persönlichen Stress bei Studienanfängern in der Humanmedizin

OpenAIRE

Schulze, Johannes; Duderstadt, Monika; Hodjat, Beheshta; Wu, Yue-Ying

2013-01-01

Die derzeitige Regelung der Zulassung zum Medizinstudium berücksichtigt die Abiturnote und Wartezeiten; universitäre Parameter können diese Kriterien modifizieren. Hierzu zählen z.B. die Leistungskurswahl, wie es an der Goethe-Universität Frankfurt gehandhabt wird. Im Rahmen der Untersuchung zu Stress und Resilienz bei Medizinstudenten haben wir bei den Studenten des 1. vorklinischen Semesters soziodemographische Daten erhoben, die einen Kohortenvergleich erlauben. Die chronische Stressbelast...

PC-BEIS: a personal computer version of the biogenic emissions inventory system

International Nuclear Information System (INIS)

Pierce, T.E.; Waldruff, P.S.

1991-01-01

The US Environmental Protection Agency's Biogenic Emissions Inventory System (BEIS) has been adapted for use on IBM-compatible personal computers (PCs). PC-BEIS estimates hourly emissions of isoprene, α-pinene, other monoterpenes, and unidentified hydrocarbons for any county in the contiguous United States. To run the program, users must provide hourly data on ambient temperature, relative humidity, wind speed, cloud cover, and a code that identifies the particular county. This paper provides an overview of the method used to calculate biogenic emissions, shows an example application, and gives information on how to obtain a copy of the program

Bewältigungsstrategien der Oberwalliser Primarlehrpersonen und Massnahmen der Gesundheitsförderung an Oberwalliser Primarschulen bei Stress und Burnout

OpenAIRE

Imhof, Barbara; Mattig, Astrid

2009-01-01

Die vorliegende Studie befasst sich mit der Gesundheitsförderung bei Stress und Burnout an den Oberwalliser Primarschulen und der Bewältigungsstrategien der Oberwalliser Primarlehrpersonen bei Stress und Burnout. Der theoretische Teil befasst sich mit Stress und Burnout und der Bewältigung von Stress und Burnout. Verschiedene Aspekte des Lehrerberufs werden näher angeschaut und es werden mögliche Massnahmen der Gesundheitsförderung bei Stress und Burnout aufgeführt. Die Untersuchung zeigt, da...

Botulinumtoxin-A in der Behandlung neurogener Blasenfunktionsstörungen bei Kindern: Funktionelle und histomorphologische Langzeitergebnisse

Directory of Open Access Journals (Sweden)

Schulte-Baukloh H

2004-01-01

Full Text Available Die etablierte Therapie der neurogenen Detrusorhyperaktivität bei Kindern besteht in der Gabe von Anticholinergika und begleitendem intermittierendem Einmalkatheterismus. Eine hohe Nebenwirkungsrate der Anticholinergika oder eine nicht ausreichende Dämpfung der Detrusoraktivität limitiert jedoch die Anwendung und zwingt nicht selten zu einem operativen Vorgehen. Wir untersuchten deshalb die Wirksamkeit von Botulinumtoxin-A (BTX-A auf die neurogene Detrusorhyperaktivität bei Kindern mit neurogener Blasenfunktionsstörung. Hierzu wurden 24 Kinder (11 Mädchen, 13 Jungen; 2,5–20 (Ø 11,9 Jahre mit maximalem Detrusordruck 40 cm H2O trotz anticholinerger Medikation in die Studie eingeschlossen. Nach urodynamischer Evaluierung wurden gewichtsadaptiert 85–300 U BTX-A (Botox(R zystoskopisch an 30–40 Stellen in den M. detrusor injiziert. Urodynamische Kontrollen erfolgten nach 1, 3 und 6 Monaten. Urodynamisch fand sich ein erhöhtes Reflexvolumen nach 1 Monat um +84 %, nach 3 Monaten um +68 % und nach 6 Monaten um +23 %. Entsprechend verhielten sich die Maximalkapazitäten: +35 % (nach 1 Monat, +23 % (nach 3 Monaten und +36 % (nach 6 Monaten. Die Maximaldrücke veränderten sich im o.g. Zeitraum um –41 %, –22 % bzw. +4 %. Die korrespondierenden Veränderungen der Inkontinenzrate betrug –46 %, –15 % bzw. –13 %. Bei 5 Kindern konnte jedoch auch mit dieser Therapie keine zufriedenstellende Drucksituation sichergestellt werden; nach der daraufhin durchgeführten Blasenaugmentation fanden sich in den Blasenresektaten histomorphologisch typische BTX-A bedingte Veränderungen, die jedoch in ihrer Ausprägung keinen signifikanten Gradienten aufwiesen. Zusammenfassend läßt sich festhalten, daß es nach Botulinumtoxin-A-Injektion in den Detrusormuskel bei der Mehrzahl der Patienten zu einer ausgeprägten und therapeutisch relevanten Verbesserung sämtlicher urodynamischer Parameter bei sehr guter Verträglichkeit des Medikamentes kommt

Gadopentate dimeglumine enhanced MR angiography (MRA) for staging AAA: a correlation with DSA and CT

International Nuclear Information System (INIS)

Arlart, I.P.; Gerlach, A.; Kolb, M.; Erpenbach, S.; Wuerstlin, S.

1997-01-01

Purpose: To evaluate a contrast-enhanced (CE) MRA sequence for staging AAA. Methods: In 24 patients (male=20, female=4, age=44-81 y) with known AAA the abdominal aorta and its branches including the iliac arteries were imaged, using a 3D GRE-FISP sequence (1.5 T, T R /T E /FA=25/6/35, slab=100-140 mm, 32 part., FOV=440-450 mm, matrix=256x256) during an i.v. infusion of 40 ml of gadopentate dimeglumine. In addition, representative axial single slices (2D breathhold FLASH-sequence: T R /T E /FA=82/5/30) were acquired following contrast application. MR-results were correlated with i.a. DSA and CT studies. Results: With CE-MRA, AAA (n=24) and iliac aneurysms (n=17) could be evaluated in all cases (sens.=100%, spec.=100%) including luminal patency and mural thrombus. 50/54 renal arteries could be identified, 4/6 accessory renal arteries (sens=66,6%, spec.=100%), 8/9 renal artery stenoses>50% (sens.=88.8%, spec.=89.3%), 1/1 renal artery occlusion and 7/8 iliac artery stenoses>50% (sens.=87.5%, spec.=97.5%) were depicted correctly. Proximal portion of sup. mes. art. could be detected and evaluated in 21/24 cases. Quantitative determination of therapeutically relevant vascular paramters using MRA was comparable to DSA and CT. (orig./AJ) [de

Pasireotid: Eine neue Therapieoption bei Morbus Cushing

Directory of Open Access Journals (Sweden)

Luger A

2012-01-01

Full Text Available Im Behandlungsalgorithmus des Morbus Cushing war bisher keine zugelassene pharmakologische Behandlungsmöglichkeit verfügbar. Mit dem Multirezeptor-Somatostatinanalogon Pasireotid steht nun mit der im April 2012 erfolgten Zulassung die erste, spezifisch für die Therapie dieses Krankheitsbildes entwickelte Substanz zur Verfügung. Die Studienevidenz belegt eine schnelle und nachhaltige Reduktion der ACTH- und Kortisolproduktion mit klinischer Besserung bei einem Großteil der Patienten.

An accurate Kriging-based regional ionospheric model using combined GPS/BeiDou observations

Science.gov (United States)

Abdelazeem, Mohamed; Çelik, Rahmi N.; El-Rabbany, Ahmed

2018-01-01

In this study, we propose a regional ionospheric model (RIM) based on both of the GPS-only and the combined GPS/BeiDou observations for single-frequency precise point positioning (SF-PPP) users in Europe. GPS/BeiDou observations from 16 reference stations are processed in the zero-difference mode. A least-squares algorithm is developed to determine the vertical total electron content (VTEC) bi-linear function parameters for a 15-minute time interval. The Kriging interpolation method is used to estimate the VTEC values at a 1 ° × 1 ° grid. The resulting RIMs are validated for PPP applications using GNSS observations from another set of stations. The SF-PPP accuracy and convergence time obtained through the proposed RIMs are computed and compared with those obtained through the international GNSS service global ionospheric maps (IGS-GIM). The results show that the RIMs speed up the convergence time and enhance the overall positioning accuracy in comparison with the IGS-GIM model, particularly the combined GPS/BeiDou-based model.

Analytische Betrachtung des Quantisierungsfehlers bei grundlegenden Rechenoperationen der digitalen Signalverarbeitung

Directory of Open Access Journals (Sweden)

W. Schlecker

2005-01-01

Full Text Available Bei der Realisierung digitaler Schaltungen mit einem ASIC oder FPGA kann die Wortbreite der Berechnungen frei gewählt werden. Um die Fläche bzw. die benötigte Hardware zu minimieren, wird versucht, die Berechnungen mit minimaler Wortbreite zu implementieren. Dabei muss jedoch das Quantisierungsrauschen, das durch das Beschränken der Wortbreite entsteht, berücksichtigt werden. Häufig wird hierzu eine worst-case Abschätzung des Fehlers gemacht oder mit Simulationen die benötigte Wortbreite bestimmt. Der vorliegende Beitrag betrachtet die Auswirkungen der Quantisierung analytisch. Dabei wird von gleichverteilten Eingangssignalen ausgegangen. Es wird das Quantisierungsrauschen in Abhängigkeit von der Eingangs- und Ausgangswortbreite bei der Multiplikation und beim Skalarprodukt betrachtet. Die Untersuchungen wurden für Runden und für Abschneiden analytisch durchgeführt und durch Simulation bestätigt.

Probleme bei der Digitalisierung analoger Messwerte

Science.gov (United States)

Plaßmann, Wilfried

Messwerte liegen häufig in analoger Form als Spannungswerte vor. Sie werden in eine digital kodierte Form umgesetzt, wenn eine (nahezu) fehlerfreie Übertragung erforderlich ist, wenn Signalverläufe gespeichert werden sollen, wenn eine Weiterverarbeitung erfolgen soll oder wenn Messungen mit sehr geringem Messfehler notwendig sind. Hier soll auf einige Probleme, die durch die Umsetzung entstehen, aus messtechnischer Sicht eingegangen werden. Stichworte: Fehler bei der Digitalisierung; Signal-Quantisierungsgeräusch-Abstand; Verbesserung des Signal-Rausch-Verhältnisses; Abtast-Halte-Glied; Aliasing; Erfassung von Momentanwerten.

Solution Method and Precision Analysis of Double-difference Dynamic Precise Orbit Determination of BeiDou Navigation Satellite System

Directory of Open Access Journals (Sweden)

LIU Weiping

2016-02-01

Full Text Available To resolve the high relativity between the transverse element of GEO orbit and double-difference ambiguity, the classical double-difference dynamic method is improved and the method, which is to determine precise BeiDou satellite orbit using carrier phase and pseudo-range smoothed by phase, is proposed. The feasibility of the method is discussed and the influence of the method about ambiguity fixing is analyzed. Considering the characteristic of BeiDou, the method, which is to fix double-difference ambiguity of BeiDou satellites by QIF, is derived. The real data analysis shows that the new method, which can reduce the relativity and assure the precision, is better than the classical double-difference dynamic method. The result of ambiguity fixing is well by QIF, but the ambiguity fixing success rate is not high on the whole. So the precision of BeiDou orbit can't be improved clearly after ambiguity fixing.

Prognostische Bedeutung der physikalischen Streßechokardiographie bei 3329 ambulanten Patienten (5jährige Langzeitstudie)

OpenAIRE

Leischik R; Dworrak B; Gülker H; Littwitz H

2005-01-01

Hintergrund und Fragestellung: Die Risikoeinschätzung ambulanter Patienten mit thorakaler Schmerzsymptomatik ist ein wichtiges klinisches Problem. Über die prognostische Bedeutung der physikalischen Streßechokardiographie (SE) bei diesem Patientenkollektiv wurde bis jetzt nicht berichtet. Patienten und Methoden: Um die prognostische Bedeutung der physikalischen Streßechokardiographie bei rein ambulanten Patienten zu untersuchen, wurden 3329 Patienten bezüglich des Auftretens schwerer Erei...

Examination of the somatostatin receptor status in non-medullary thyroid cancer; Untersuchungen zum Somatostatinrezeptor-Status bei nicht-medullaeren Schilddruesenkarzinomen

Energy Technology Data Exchange (ETDEWEB)

Goerges, R.; Brandt-Mainz, K.; Bockisch, A. [Essen Univ. (Gesamthochschule) (Germany). Klinik und Poliklinik fuer Nuklearmedizin; Kahaly, G. [Mainz Univ. (Germany). Klinik und Poliklinik fuer Medizin - Endokrinologie und Stoffwechselerkrankungen; Mueller-Brand, J.; Maecke, H. [Kantonsspital Basel (Switzerland). Inst. fuer Nuklearmedizin; Walgenbach, S. [Mainz Univ. (Germany). Klinik und Poliklinik fuer Allgemein- und Abdominalchirurgie; Bruns, C. [Praeklinische Forschung Novartis, Basel (Switzerland); Andreas, J. [Universitaetsklinik Mainz (Germany). Klinik und Poliklinik fuer Nuklearmedizin

1999-06-01

Aim: Recent in-vitro and in-vivo studies demonstrated a somatostatin receptor expression in some non-medullary thyroid carcinomas. In this study we investigated the somatostatin receptor status for this particular tumor entity in a larger patient group. Subject and methods: We compared 131-iodine with 111-In-pentetreotide scans in 24 patients with metastasizing, non-medullary thyroid cancer. The findings were correlated with other imaging modalities. Additionally, we performed receptor autoradiography in one patient, octreotide therapy in another patient and administration of 90-Y- and 111-In-DOTATOC in 2 consecutive patients. Results: In the 15 patients with papillary or follicular carcinoma, 111-In-pentetreotide was inferior to 131-I in 8/15, equal in 1/15, and superior in 6/15 patients. In 8/9 of the patients with Huerthle cell cacinoma, metastases showed a 111-In-pentetreotide accumulation of various intensity, while 131-iodine scans were negative except for one patient. 111-In-pentetreotide was equal or superior compared to 201-Tl or 99m-Tc-sestamibi, but for the most part inferior in comparison with 18-F-FDG-PET. The findings of 111-In-pentetreotide scintigraphy correlated well with the receptor autoradiography and the accumulation of DOTATOC, but not with the therapeutic effect of `cold` octreotide on the thyroid cancer metastases. Conclusions: Several metastases of papillary and follicular carcinoma, and the majority of Huerthle cell cancer metastases can express somatostatin receptors. 111-In-pentetreotide scintigraphy is a promising tool for localization of metastases especially in Huerthle cell cancer or if PET is not available, and may be useful for selection of possible candidates, if therapeutic effective {beta}-emitting somatostatin analogues will be available for routine application. (orig.) [Deutsch] Ziel: in aktuellen In-vitro und In-vivo-Untersuchungen wurde eine Somatostatinrezeptor-Expression bei einigen nicht

Untersuchungen zum Fettsäurestoffwechsel bei koronarer Herzkrankheit

OpenAIRE

Richter, Wolf-Stefan

2001-01-01

Die nicht-invasive bildgebende Diagnostik hat bei koronarer Herzkrankheit einen wichtigen Stellenwert für die Diagnosestellung und Therapieplanung. In diesem Zusammenhang liefern nuklearmedizinische Verfahren wichtige Daten zur Gewebsperfusion und erlauben die bildliche Darstellung und Quantifizierung relevanter Details des kardiomyozytären Stoffwechsels. Die quantitativ bedeutendste Methode der nuklearmedizinischen Herzdiagnostik ist die Perfusionsszintigraphie mit Tl-201 oder einem der Tc-9...

New screening system for unruptured cerebral aneurysms; Combination of an expert system and DSA examination

Energy Technology Data Exchange (ETDEWEB)

Samejima, Hirotsugu; Ushikubo, Yukio; Mizokami, Toru [Toho Univ., Tokyo (Japan). School of Medicine; and others

1990-08-01

We have designed a screening system to diagnose unruptured aneurysms, including the use of digital subtraction angiography (DSA). We surveyed 115 patients who had undergone clipping procedures after subarachnoid hemorrhage (SAH) and questioned them with regard to the subjective symptoms. Sixty-eight of 92 patients who returned the questionnaire reported, prior to rupture, headache,eye pain, and neck pain most frequently, and also impairment of extraocular movements, ptosis, visual field defects, and motor and sensory disturbances. Nineteen (47.5%) of 40 patients who had complete pain relief after surgery complained of headache from 1 week to 1 month before SAH. In addition, nine patients (22.5%) complained of headache for several years, and were also pain-free after surgery. For the indication of DSA, we employed an expert system based on fuzzy set theory. Seven groups of parameters are: Group 1, a basic questionnaire concerning age, sex, and past and family histories; Group 2, 15 warning signs selected on the basis of retrospective study; and Groups 3-7, detailed questions concerning each sign. Scoring weights assigned to each condition based on the results of the retrospective study, and threshold values were determined by several neurosurgeons. The certainty factors for intermediate hypotheses were calculated from these weights and threshold values and summed up, from which the conclusion was obtained. Twelve new cases of unruptured cerebral aneurysm were diagnosed using this screening system. This system may improve the ability to diagnose cerebral aneurysms before rupture. (author).

The stepchild of intestinal diagnostics. Evaluation of radiological methods to diagnose leiomyomas of the small bowel; Das Stiefkind der Darmdiagnostik. Wertigkeit radiologischer Diagnosemoeglichkeiten von Leiomyomen im Duenndarm

Energy Technology Data Exchange (ETDEWEB)

Keberle, M.; Wittenberg, G.; Jenett, M.; Hahn, D. [Wuerzburg Univ. (Germany). Inst. fuer Roentgendiagnostik; Mueller, J.G. [Wuerzburg Univ. (Germany). Pathologisches Inst.

1998-11-01

Purpose: Various radiological methods to diagnose small bowel neoplasmas and problems of differential diagnosis specially considerating leiomyomas are discussed. Patients and methods: Two patients with leiomyoma of the ileum underwent enteroclysis, computed tomography of the abdomen, intra-arterial DSA and colour Doppler sonography. Another patient with leiomyosarcoma just underwent CT of the abdomen with CT-guided biopsy. Results: Due to the homogenous density and the smooth surface of the tumors in computed tomography and respectively enteroclysis and the presentation of the tumor vascularisation in the angiography and Colour Doppler sonography in both patients a leiomyoma of the small bowel was diagnosed. Postoperatively this diagnosis was histologically confirmed. The CT-findings of the patient with leiomyosarcoma were not suspicious of a malignant tumor. Conclusion: Radiologically it is not possible to determine the dignity of smooth muscle cell tumors safely. That is the reason why the diagnosis has to be achieved operatively. But the histopathological diagnosis based on the mitotic rate may be difficult. Therefore the after care has to be carried out thoroughly. (orig.) [Deutsch] Ziel: Es werden Diagnosemoeglichkeiten von Duenndarmtumoren und differentialdiagnostische Problemstellungen unter besonderer Beruecksichtigung des Leiomyoms diskutiert. Patienten und Methode: Bei zwei Patienten mit einem Leiomyom des Ileums wurde jeweils ein Enteroklysma nach Sellink, eine CT des Abdomens, eine intraarterielle DSA mit selektiver Darstellung der Art.mesenterica superior und eine farbkodierte Duplexsonographie (FKDS) durchgefuehrt. Bei einem Patienten mit Leiomyosarkom wurde lediglich eine CT des Abdomens mit CT-gesteuerter Biopsie durchgefuehrt. Ergebnisse: Aufgrund der homogenen Dichtewerte und der glatten Begrenzung der Tumoren in der CT bzw. dem Enteroklysma, ergaenzt durch die farbdopplersonographische und angiographische Darstellung der Tumorgefaesse, wurde bei

Furosemide urogram in patients with neobladder; Das Diureseurogramm bei Patienten mit Harnblasenersatz

Energy Technology Data Exchange (ETDEWEB)

Merkle, E.M. [Univ. Ulm (Germany). Abt. Radiologie; Aschoff, A.J. [Univ. Ulm (Germany). Abt. Radiologie; Bachor, R. [Univ. Ulm (Germany). Abt. fuer Urologie; Vogel, J. [Univ. Ulm (Germany). Abt. Radiologie; Merk, J. [Univ. Ulm (Germany). Abt. Radiologie; Brambs, H.J. [Univ. Ulm (Germany). Abt. Radiologie

1996-11-01

Purpose: To differentiate between urodynamically relevant obstruction and functionally unimportant dilation of the upper urinary tract in patients with neobladder using a modified furosemide urogram. Method: An excretory urogram with furosemide loading was carried out in 19 patients with neobladder and sonographically and urographically confirmed dilation of the upper urinary tract. Once strong contrasting of the renal pelves and calyces has been achieved, 20 mg of furosemide were applied and late radiographs were obtained at 15 min and 30 min, respectively. An obstruction was defined as increasing dilation of the renal pelves and calices during forced diuresis and lack of washout effect of the contrast medium. Results: In 32 cases, the renoureteral unit (RUU) was dilated on ultrasound. Of these, 25 RUU`s showed good emptyness of contrast medium upon stimulation of diuresis, six RUU`s returned a borderline findings, while one RUU was found to exhibit a decompensated anastomotic stenosis, which was dilated. Two further patients with bordeline findings were later treated surgically due to their pain symptoms. No patient required further preoperative diagnostic procedures. Conclusions: The modified furosemide urogram represents a cost-effective diagnostic orientation strategy in patients with neobladder and dilated renal pelves and calyses and is both well-tolerated by patients and meets with broad acceptance from the urologic staff. (orig.) [Deutsch] Ziel: Differenzierung zwischen urodynamisch relevanter Obstruktion und funktionell bedeutungsloser Dilatation des oberen Harntraktes bei Patienten mit Harnblasenersatz durch ein modifiziertes Diureseurogramm. Methodik: Bei 19 Patienten mit Harnableitung und sonographisch sowie urographisch nachgewiesener Erweiterung des oberen Harntraktes wurde ein Ausscheidungsurogramm mit Furosemidbelastung durchgefuehrt. Bei kraeftiger Kontrastierung des erweiterten Nierenbeckenkelchsystems (NBKS) wurden 20 mg Furosemid appliziert und

A Aderência dos Pronunciamentos Contábeis do CPC às Normas Internacionais de Contabilidade

Directory of Open Access Journals (Sweden)

Jorge Andrade Costa

2012-09-01

Full Text Available A convergência para os padrões contábeis internacionais tem se tornado um assunto relevante, com agenda definida para sua adesão em muitos países ao redor do mundo. No Brasil, coube ao CPC a responsabilidade de emitir pronunciamentos contábeis de acordo com as normas IFRS. Cada documento emitido pelo CPC corresponde a uma norma internacional de contabilidade emitida pelo IASB. Este trabalho tem como objetivo comparar os pronunciamentos do CPC com as normas do IASB e verificar a existência de diferenças entre os mesmos. Para tanto, realizou-se uma pesquisa documental aos pronunciamentos do CPC e às normas do IASB. Utilizou-se a técnica da análise de conteúdo, tendo o tema como unidade de significação. O universo de análise compreendeu os 65 pronunciamentos técnicos que estão sendo utilizados nas demonstrações contábeis das companhias brasileiras, emitidos pelo CPC entre os anos de 2007 a 2011. Os resultados apontaram para a existência de diferenças entre os pronunciamentos emitidos pelo CPC e as normas emitidas pelo IASB, as quais foram agrupadas em quatro categorias de análise. Após análise, concluiu-se que as diferenças apontadas não prejudicam a declaração de que as demonstrações contábeis consolidadas brasileiras, preparadas de acordo com os CPCs estão de acordo com as normas do IASB. Palavras-chave: CPC, IFRS, IASB, demonstrações contábeis

Mitbestimmung von Studierenden bei der Qualitätssicherung und Hochschulentwicklung

DEFF Research Database (Denmark)

Lippert, Ingmar

2005-01-01

Hochschule hat bestimmte Aufgaben. Sie soll durch Forschung und Lehre Wissen und Methoden in die Gesellschaft tragen. Sie soll auch direkt andere gesellschaftliche Institutionen beraten. Bei diesen Interaktionen soll aber – und das ist so spezifisch für Hochschulen – die gesellschaftliche Praxis ...

PET activation in basal ganglia disorders: Parkinson`s disease and dystonia; PET-Aktivierungsstudien bei Basalganglienerkrankungen: Morbus Parkinson und Dystonien

Energy Technology Data Exchange (ETDEWEB)

Ceballos-Baumann, A.O. [Neurologische Klinik, Technische Univ. Muenchen (Germany); Boecker, H. [Neurologische Klinik, Technische Univ. Muenchen (Germany); Conrad, B. [Neurologische Klinik, Technische Univ. Muenchen (Germany)

1997-03-01

This article reviews PET activation studies with performance of different motor paradigms (joy-stick movements, imagination of movement, writing) in patients with movement disorders. The focus will be on Parkinson`s disease (PD) and dystonia. PET findings will be related to clinical and electrophysiological observations. PET activation studies before and after therapeutic interventions such as pallidotomy in Parkinson`s disease and botulinum toxin in writer`s cramp are described. The contribution of PET activation studies to the understanding of the pathophysiology of dystonia and PD is discussed. (orig.) [Deutsch] Der Beitrag beschreibt verschiedene PET-Aktivierungsstudien mit motorischen Paradigmen (`joystick`-Bewegungen, Vorstellung von Bewegung, Schreiben) bei Bewegungsstoerungen, im wesentlichen bei Patienten mit Dystonie, einer Hyperkinese, und Morbus Parkinson als Hypokinese. Die experimentellen Befunde werden mit der Klinik in Bezug gebracht. Neue Untersuchungen vor und nach therapeutischen Interventionen, wie die stereotaktische Pallidotomie bei Parkinson und die Botulinum-Toxin-Therapie bei Schreibkrampf, werden beschrieben. Der Beitrag von PET-Aktivierungsstudien zum Verstaendnis der Pathophysiologie von Bewegungsstoerungen wird diskutiert. (orig.)

TU-H-CAMPUS-IeP3-02: Neurovascular 4D Parametric Imaging Using Co-Registration of Biplane DSA Sequences with 3D Vascular Geometry Obtained From Cone Beam CT

Energy Technology Data Exchange (ETDEWEB)

Balasubramoniam, A; Bednarek, D; Rudin, S; Ionita, C [Toshiba Stroke and Vascular Research Centre, SUNY at Buffalo (United States)

2016-06-15

Purpose: To create 4D parametric images using biplane Digital Subtraction Angiography (DSA) sequences co-registered with the 3D vascular geometry obtained from Cone Beam-CT (CBCT). Methods: We investigated a method to derive multiple 4D Parametric Imaging (PI) maps using only one CBCT acquisition. During this procedure a 3D-DSA geometry is stored and used subsequently for all 4D images. Each time a biplane DSA is acquired, we calculate 2D parametric maps of Bolus Arrival Time (BAT), Mean Transit Time (MTT) and Time to Peak (TTP). Arterial segments which are nearly parallel with one of the biplane imaging planes in the 2D parametric maps are co-registered with the 3D geometry. The values in the remaining vascular network are found using spline interpolation since the points chosen for co-registration on the vasculature are discrete and remaining regions need to be interpolated. To evaluate the method we used a patient CT volume data set for 3D printing a neurovascular phantom containing a complete Circle of Willis. We connected the phantom to a flow loop with a peristaltic pump, simulating physiological flow conditions. Contrast media was injected with an automatic injector at 10 ml/sec. Images were acquired with a Toshiba Infinix C-arm and 4D parametric image maps of the vasculature were calculated. Results: 4D BAT, MTT, and TTP parametric image maps of the Circle of Willis were derived. We generated color-coded 3D geometries which avoided artifacts due to vessel overlap or foreshortening in the projection direction. Conclusion: The software was tested successfully and multiple 4D parametric images were obtained from biplane DSA sequences without the need to acquire additional 3D-DSA runs. This can benefit the patient by reducing the contrast media and the radiation dose normally associated with these procedures. Partial support from NIH Grant R01-EB002873 and Toshiba Medical Systems Corp.

TU-H-CAMPUS-IeP3-02: Neurovascular 4D Parametric Imaging Using Co-Registration of Biplane DSA Sequences with 3D Vascular Geometry Obtained From Cone Beam CT

International Nuclear Information System (INIS)

Balasubramoniam, A; Bednarek, D; Rudin, S; Ionita, C

2016-01-01

Purpose: To create 4D parametric images using biplane Digital Subtraction Angiography (DSA) sequences co-registered with the 3D vascular geometry obtained from Cone Beam-CT (CBCT). Methods: We investigated a method to derive multiple 4D Parametric Imaging (PI) maps using only one CBCT acquisition. During this procedure a 3D-DSA geometry is stored and used subsequently for all 4D images. Each time a biplane DSA is acquired, we calculate 2D parametric maps of Bolus Arrival Time (BAT), Mean Transit Time (MTT) and Time to Peak (TTP). Arterial segments which are nearly parallel with one of the biplane imaging planes in the 2D parametric maps are co-registered with the 3D geometry. The values in the remaining vascular network are found using spline interpolation since the points chosen for co-registration on the vasculature are discrete and remaining regions need to be interpolated. To evaluate the method we used a patient CT volume data set for 3D printing a neurovascular phantom containing a complete Circle of Willis. We connected the phantom to a flow loop with a peristaltic pump, simulating physiological flow conditions. Contrast media was injected with an automatic injector at 10 ml/sec. Images were acquired with a Toshiba Infinix C-arm and 4D parametric image maps of the vasculature were calculated. Results: 4D BAT, MTT, and TTP parametric image maps of the Circle of Willis were derived. We generated color-coded 3D geometries which avoided artifacts due to vessel overlap or foreshortening in the projection direction. Conclusion: The software was tested successfully and multiple 4D parametric images were obtained from biplane DSA sequences without the need to acquire additional 3D-DSA runs. This can benefit the patient by reducing the contrast media and the radiation dose normally associated with these procedures. Partial support from NIH Grant R01-EB002873 and Toshiba Medical Systems Corp.

Die Dankesrede bei der Preisverleihung

Directory of Open Access Journals (Sweden)

Elenmari Pletikos Olof

2012-12-01

Full Text Available Festliche Preisverleihungen sind Gelegenheiten, bei denen von den Preisträgerneine kurze Rede erwartet wird. Obwohl die Dankesrede eine kleinere Randgattung innerhalb des epideiktischen Genres ist, steht sie im Mittelpunkt des Ereignisses. Rhetorikhandbücher geben zahlreiche Ratschläge, wie eine gute Festrede vorbereitet werden soll, um zu unterhalten, zu bewegen und zu belehren. Ziel dieser Untersuchung ist es festzustellen, welche Eigenschaften der Dankesrede die Zuhörer als erwünscht oder unerwünscht wahrnehmen und welche Charakteristika am meisten zur Qualität festlicher Dankesreden beitragen. Das Korpus der gesprochenen Texte bilden 30 Dankesreden anlässlich kroatischer Preisverleihungen in den Bereichen Schauspiel, Sport, Musik, Fernsehen, Literatur und Wirtschaft. Die Audio-Aufnahmen der Dankesreden wurden einer Gruppe von Hörern zur Bewertung in folgenden Kategorien vorgelegt: interessant, geistreich, hoher Sprachstil, feierlich, emotiv, persönlich, originell, bescheiden, vorbereitet und spontan. Zusätzlich wurde zu jeder Rede die offene Frage gestellt, was dem Zuhörer an der Rede gefallen oder nicht gefallen habe. Die Resultate der Perzeptionsanalye lassen erkennen, dass die Interessantheit einer Rede mit der Eigenschaft des Geistreichen, des Originellen, des Emotionalen und des Persönlichen in Verbindung gebracht wird und die Eigenschaft des Festlichen im Wesentlichen nur mit dem hohen Sprachstil und der Vorbereitetheit des Textes korreliert. Einige Eigenschaften können sowohl erwünscht als auch unerwünscht sein, z. B. Dialekt, Persönliches und Kürze. Die besten Dankesreden haben Eigenschaften, die im Grunde schwer miteinander zu verbinden sind: Einerseits soll der Text vorbereitet sein (hoher Stil, Wortwahl, Figuren, Originalität der Geschichte, Humor, andererseits wird bei der Ausführung Spontaneität (Aufrichtigkeit, Emotionalität, Persönlichkeit erwartet.

Retrospektive Analyse von Zufallsbefunden, die bei Patienten mit kutanem malignen Malignom durch (18) F-Fluordeoxyglucose-PET/CT erhoben wurden.

Science.gov (United States)

Conrad, Franziska; Winkens, Thomas; Kaatz, Martin; Goetze, Steven; Freesmeyer, Martin

2016-08-01

Bei der (18) F-Fluordeoxyglucose-Positronenemissionstomographie/Computertomographie (FDG-PET/CT) ergeben sich häufig Zufallsbefunde. In der vorliegenden Studie konzentrierten wir uns auf mittels FDG-PET/CT erhaltene Zufallsbefunde bei Patienten mit kutanem Melanom und überprüften deren Relevanz hinsichtlich weiterer diagnostischer Maßnahmen und Interventionen. Die Krankenakten von 181 konsekutiven Melanom-Patienten wurden retrospektiv ausgewertet, um das Management von Zufallsbefunden zu dokumentieren. Der Schwerpunkt lag dabei auf den histologischen Befunden. Bei 33 von 181 (18 %) Patienten lagen 39 relevante Zufallsbefunde vor, und zwar im Kolorektalbereich (n = 15 Patienten), in der Schilddrüse (n = 8), der Prostata (n = 2), dem Bewegungsapparat (n = 2), in Lymphknoten (n = 2), der Parotis (n = 1), den Mandeln (n = 1), den Nieren (n = 1) und der Gallenblase (n = 1). Bei 25 Patienten schlossen sich weitere diagnostische Verfahren an, wobei in 21 Fällen ein klinisches Korrelat nachgewiesen wurde. Bei 16 von 21 Patienten ergab sich eine Neoplasie, darunter fünf maligne Läsionen (vier Kolonkarzinome und ein Prostatakarzinom). Die Malignome wurden frühzeitig diagnostiziert und in der Mehrzahl der Fälle erfolgreich entfernt. Der Einsatz der FDG-PET/CT als Routine-Diagnostik wird in den Leitlinien empfohlen und ist indiziert bei malignem Melanom ab Stadium IIC. In dieser Studie wurden auf effektive Weise ansonsten nicht erkannte Krebserkrankungen, insbesondere Kolonkarzinome, detektiert. In den meisten Fällen war eine frühe Intervention möglich. Zufallsbefunde durch FDG-PET/CT sollten, unter Berücksichtigung des Zustands und der Wünsche des Patienten, mit den geeigneten diagnostischen Maßnahmen abgeklärt werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Der Einfluss von Alitretinoin auf die Lebensqualität bei Patienten mit schwerem chronischen Handekzem: FUGETTA - Beobachtungsstudie unter Praxisbedingungen.

Science.gov (United States)

Augustin, Matthias; Thaçi, Diamant; Kamps, Anja

2016-12-01

Alitretinoin ist die einzige zugelassene Behandlung für schweres chronisches Handekzem (CHE), das refraktär gegenüber potenten topischen Corticosteroiden ist. Bei dieser Studie (FUGETTA) wurde die Wirksamkeit von leitliniengerecht angewendetem oralem Alitretinoin sowie dessen Einfluss auf die Lebensqualität (LQ) bei Patienten mit schwerem refraktärem CHE beurteilt. Multizentrische, offene, nichtinterventionelle Beobachtungsstudie, durchgeführt in Deutschland. Die Patienten wurden nach Ermessen ihres behandelnden Arztes mit Alitretinoin 10 mg oder 30 mg einmal täglich über maximal 24 Wochen behandelt. Die Wirksamkeit wurde anhand des Physician Global Assessment (PGA) und des Dermatology Life Quality Index (DLQI) bewertet. Zudem wurden unerwünschte Ereignisse (UE) erfasst. Die Studienpopulation bestand aus 658 Patienten (30 mg: n = 581; 10 mg: n = 77). Bei Beobachtungsbeginn litten die meisten Patienten (83 %) gemäß PGA an einem schweren CHE. Bei Beobachtungsende war das Handekzem bei 48 % der Patienten gemäß PGA vollständig oder fast vollständig abgeheilt (30 mg: 49 %; 10 mg: 43 %). Die mittlere Verbesserung des DLQI-Scores in Woche 24 betrug 58 % (30 mg: mittlere [SD] Veränderung gegenüber dem Ausgangswert -10,4 [8,04]) und 70 % (10 mg: mittlere [SD] Veränderung gegenüber dem Ausgangswert -10,8 [7,29]). Die Gesamtinzidenz von NW war niedrig und in den beiden Gruppen ähnlich. Alitretinoin führte zu einer schnellen, deutlichen Verbesserung der LQ bei Patienten mit schwerem CHE. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

MRI of the musculature in patients with myalgia - indications and imaging results; MRT der Muskulatur bei Myalgien - Indikationen und Bildbefunde

Energy Technology Data Exchange (ETDEWEB)

Beese, M.S. [Universitaetsklinik Hamburg-Eppendorf (Germany). Radiologische Klinik; Winkler, G. [Universitaetsklinik Hamburg-Eppendorf (Germany). Neurologische Klinik; Maas, R. [Universitaetsklinik Hamburg-Eppendorf (Germany). Radiologische Klinik; Buechler, E. [Universitaetsklinik Hamburg-Eppendorf (Germany). Radiologische Klinik

1996-05-01

241 patients suffering from myalgic symptoms were examined by axial scans of the muscular system with T1w and STIR-sequences. All patients underwent a complete neuromuscular examination, which included an MRI guided muscle-biopsy of 203 patients. The images were retrospectively analysed as to the typical characteristics of differential diagnosis. In cases of idiopathic or bacterial/viral induced myositis, primary vasculitis, and rhabdomyolysis, edematous changes of the muscles could always be found. Abscesses were only found in bacterial myositis. In cases of poly- and dermatomyositis as well as inclusion-body-myositis, MRI showed a uniform distribution pattern with emphasis on the quadriceps muscles. In contrast to other neuromuscular diseases in bacterial induced myositis, focal myositis, and rhabdomyolysis a strong contrast agent enhancement was seen. All patients with myalgic syndromes without any other additional neuropathological findings and 86% of the patients suffering from polymyalgia rheumatica had normal MR-findings. MRI allows a correct exclusion of an inflammatory, tumorous, or rhabdomyolitic cause of a myalgia and leads to pathognomonic findings for these diseases. Diseases belonging to the group of endocrine, toxic, or metabolic myopathies might be normal in MRI. (orig./MG) [Deutsch] Bei 241 Patienten mit myalgischen Beschwerden wurden axiale Aufnahmen der Muskulatur mit T1w- und STIR-Sequenzen angefertigt. Bei allen Patienten wurde eine vollstaendige neuromuskulaere Untersuchung durchgefuehrt, die bei 203 Patienten eine MRT-gezielte Muskelbiopsie beinhaltete. Das Bildmaterial wurde retrospektiv hinsichtlich differentialdiagnostischer Charakteristika analysiert. Bei idiopathischen und erregerbedingten Myositiden, primaeren Vaskulitiden und bei Rhabdomyolysen bestanden ohne Ausnahme oedematoese Veraenderungen der Muskulatur. Abszessformationen wurden nur bei erregerbedingten Myositiden vorgefunden. Bei Poly- und Dermatomyositiden sowie

Osteoporose bei Mb. Bechterew - neue Ansätze

OpenAIRE

Obermayer-Pietsch B; Aglas F; Hermann J; Leb G; Tauber G

1999-01-01

Eine axiale Osteoporose und daraus resultierende vertebrale Kompressionsfrakturen sind häufige Symptome eines Mb. Bechterew (MbB, Spondylarthritis ankylosans). Als ein möglicher genetischer Faktor der Osteoporose wurde eine Assoziation der Knochendichte (BMD) mit BsmI- und FokI-Polymorphismen im Vitamin D-Rezeptor-(VDR-)Gen publiziert. In der vorliegenden Studie wurden die Beziehungen zwischen diesen Polymorphismen, Knochenstoffwechsel, BMD und Aktivitätsindizes bei Patienten mit MbB untersuc...

Magnetic resonance spectroscopy in schizophrenia. Possibilities and limitations; Magnetresonanzspektroskopie bei Schizophrenie. Moeglichkeiten und Grenzen

Energy Technology Data Exchange (ETDEWEB)

Wobrock, T. [Universitaetsklinikum des Saarlandes, Homburg/Saar (Germany). Klinik fuer Psychiatrie und Psychotherapie; Universitaetsklinikum des Saarlandes, Klinik fuer Psychiatrie und Psychotherapie, Homburg/Saar (Germany); Scherk, H.; Falkai, P. [Universitaetsklinikum des Saarlandes, Homburg/Saar (Germany). Klinik fuer Psychiatrie und Psychotherapie

2005-02-01

Magnetic resonance spectroscopy is a noninvasive investigative technique for in vivo detection of biochemical changes in neuropsychiatric disorders for which especially proton ({sup 1}H-MRS) and phosphorus ({sup 31}P-MRS) magnetic resonance spectroscopy have been used. In this review we explain the principles of MRS and summarize the studies in schizophrenia. A systematic literature review was carried out for {sup 1}H-MRS studies investigating schizophrenic patients compared to controls. The inconsistent results in the cited studies may be due to different study population, specific neuroimaging technique, and selected brain regions. Frequent findings are decreased PME and increased PDE concentrations ({sup 31}P-MRS) linked to altered metabolism of membrane phospholipids and decreased N-acetylaspartate (NAA) or NAA/choline ratio ({sup 1}H-MRS) linked to neuronal damage in frontal (DLPFC) or temporal regions in patients with schizophrenia. These results contribute to the disturbed frontotemporal-thalamic network assumed in schizophrenia and are supported by additional functional neuroimaging, MRI morphometry, and neuropsychological evaluation. The combination of the described investigative techniques with MRS in follow-up studies may provide more specific clues for understanding the pathogenesis and disease course in schizophrenia. (orig.) [German] Die Magnetresonanzspektroskopie (MRS) stellt ein nichtinvasives Verfahren dar, mit dem in vivo biochemische Veraenderungen spezifischer Hirnregionen bei verschiedenen psychiatrischen Erkrankungen untersucht werden koennen. Dabei werden insbesondere die Protonenmagnetresonanzspektroskopie ({sup 1}H-MRS) sowie die Phosphormagnetresonanzspektroskopie ({sup 31}P-MRS) verwendet. In der vorliegenden Uebersichtsarbeit werden die methodischen Grundlagen erlaeutert sowie die Befundlage bei der Schizophrenie referiert. Fuer die Darstellung der Studien zur {sup 1}H-MRS bei schizophrenen Patienten im Vergleich zu einer Kontrollgruppe

HRCT of the lung in collagen vascular diseases; HRCT der Lunge bei Kollagenosen

Energy Technology Data Exchange (ETDEWEB)

Diederich, S. [Inst. fuer Klinische Radiologie, Westfaelische Wilhelms-Univ., Muenster (Germany); Roos, N. [Inst. fuer Klinische Radiologie, Westfaelische Wilhelms-Univ., Muenster (Germany); Schmitz-Linneweber, B. [Medizinische Klinik B, Westfaelische Wilhelms-Univ., Muenster (Germany); Gaubitz, M. [Medizinische Klinik B, Westfaelische Wilhelms-Univ., Muenster (Germany); Peters, P.E. [Inst. fuer Klinische Radiologie, Westfaelische Wilhelms-Univ., Muenster (Germany)

1996-07-01

bei progressiver Systemsklerose (PSS, Sklerodermie), systemischem Lupus erythematodes (SLE), `mixed connective tissue disease` (MCTD, Sharp-Syndrom), Sjoegren-Syndrom, Mischkollagenose (`Overlap`syndrom) und rheumatoider Arthritis (RA) werden dargestellt. Ausserdem werden fuer die einzelnen Krankheitsbilder jeweils spezifische Phaenomene erlaeutert wie die Oesophagusbeteiligung bei PSS, akute Pneumonitis oder pulmonale Haemorrhagie bei SLE, lymphoproliferative Erkrankungen beim Sjoegren-Syndrom und nekrobiotische Rundherde bei RA. (orig.)

Acute Antibody-Mediated Rejection in Presence of MICA-DSA and Successful Renal Re-Transplant with Negative-MICA Virtual Crossmatch.

Directory of Open Access Journals (Sweden)

Yingzi Ming

Full Text Available The presence of donor-specific alloantibodies (DSAs against the MICA antigen results in high risk for antibody-mediated rejection (AMR of a transplanted kidney, especially in patients receiving a re-transplant. We describe the incidence of acute C4d+ AMR in a patient who had received a first kidney transplant with a zero HLA antigen mismatch. Retrospective analysis of post-transplant T and B cell crossmatches were negative, but a high level of MICA alloantibody was detected in sera collected both before and after transplant. The DSA against the first allograft mismatched MICA*018 was in the recipient. Flow cytometry and cytotoxicity tests with five samples of freshly isolated human umbilical vein endothelial cells demonstrated the alloantibody nature of patient's MICA-DSA. Prior to the second transplant, a MICA virtual crossmatch and T and B cell crossmatches were used to identify a suitable donor. The patient received a second kidney transplant, and allograft was functioning well at one-year follow-up. Our study indicates that MICA virtual crossmatch is important in selection of a kidney donor if the recipient has been sensitized with MICA antigens.

A Modified Differential Coherent Bit Synchronization Algorithm for BeiDou Weak Signals with Large Frequency Deviation.

Science.gov (United States)

Han, Zhifeng; Liu, Jianye; Li, Rongbing; Zeng, Qinghua; Wang, Yi

2017-07-04

BeiDou system navigation messages are modulated with a secondary NH (Neumann-Hoffman) code of 1 kbps, where frequent bit transitions limit the coherent integration time to 1 millisecond. Therefore, a bit synchronization algorithm is necessary to obtain bit edges and NH code phases. In order to realize bit synchronization for BeiDou weak signals with large frequency deviation, a bit synchronization algorithm based on differential coherent and maximum likelihood is proposed. Firstly, a differential coherent approach is used to remove the effect of frequency deviation, and the differential delay time is set to be a multiple of bit cycle to remove the influence of NH code. Secondly, the maximum likelihood function detection is used to improve the detection probability of weak signals. Finally, Monte Carlo simulations are conducted to analyze the detection performance of the proposed algorithm compared with a traditional algorithm under the CN0s of 20~40 dB-Hz and different frequency deviations. The results show that the proposed algorithm outperforms the traditional method with a frequency deviation of 50 Hz. This algorithm can remove the effect of BeiDou NH code effectively and weaken the influence of frequency deviation. To confirm the feasibility of the proposed algorithm, real data tests are conducted. The proposed algorithm is suitable for BeiDou weak signal bit synchronization with large frequency deviation.

Taxonomia de distorções contábeis

Directory of Open Access Journals (Sweden)

José Humberto da Cruz Cunha

2017-05-01

Full Text Available http://dx.doi.org/10.5007/1518-2924.2017v22n49p127 Discute o uso de uma taxonomia de distorções contábeis provenientes de erros e fraudes, voltada para o uso dos auditores na análise dos riscos e escolha dos procedimentos de auditoria. Sua elaboração segue as orientações conceituais da classificação facetada, por meio de levantamento conceitual em pesquisa bibliográfica. A taxonomia apresentada possui como categorias fundamentais as fases da informação, aspectos essenciais, afirmações, ciclos de recursos, subciclos de recursos, distorções contábeis e afirmações (objetivos de auditoria. É apresentada a metodologia de elaboração da taxonomia, bem como a sua aplicabilidade na auditoria contábil como instrumento de organização da informação e do conhecimento. Conclui que, a partir dos exemplos utilizados, é possível afirmar que a taxonomia orienta a análise das distorções como uma trilha de auditoria, padronizando os conceitos identificados na linguagem natural em uma estrutura de classificação padronizada.

Imaging anatomy of dorsal pancreatic artery in patients with diabetes: a comparative study between CTA and DSA

International Nuclear Information System (INIS)

Lin Yuning; Li Hui; Yang Xizhang; Chen Ziqian; Tan Jianming; Zhong Qun; Yang Li; Wu Zhixian; Li Huimin; Huang Yisheng

2011-01-01

Objective: To investigate the clinical value of 64-section CT angiography (CTA) in detecting the origin of dorsal pancreatic artery (DPA). Methods: Ninety-seven consecutive patients with diabetes received transcatheter infusion of autologous bone marrow-derived stem cell transplantation into DPA. Abdominal CTA was performed in 42 patients before angiography. Celiac trunk, splenic, common hepatic and superior mesenteric arteries were reconstructed in order to locate the origin and traveling course of DPA. A routine angiography of both celiac and superior mesenteric arteries was performed for the demonstration of DPA. Further angiography of splenic and gastroduodenal arteries was carried out if necessary. Taking DSA images as the reference standard, the sensitivity, specificity and accuracy of CTA for DPA detection were calculated. Results: DPA was the main supply artery of pancreas in 85.7% patients (36/42). CTA demonstrated the origin of DPA in 35 cases, although one of which was confirmed to be misjudged (false positive). In seven cases CTA could not demonstrate DPA, and DSA proved that 2 of them was misjudged (false negative). The sensitivity,specificity and accuracy of CTA for DPA detection were 94.4%, 83.3% and 92.9%, respectively. Conclusion: 64-section CTA can accurately detect the origin of main supply artery of pancreas, which is of great value in guiding the interventional procedure for pancreatic diseases. (authors)

Adjuvant chemo- and radiotherapy in gastrointestinal tumors; Adjuvante Chemo- und Strahlentherapie bei gastrointestinalen Tumoren

Energy Technology Data Exchange (ETDEWEB)

Sendler, A. [Technische Univ. Muenchen (Germany). Chirurgische Klinik und Poliklinik; Feldmann, H.J. [Technische Univ. Muenchen (Germany). Inst. und Poliklinik fuer Strahlentherapie und Radiologische Onkologie; Fink, U. [Technische Univ. Muenchen (Germany). Chirurgische Klinik und Poliklinik; Molls, M. [Technische Univ. Muenchen (Germany). Inst. und Poliklinik fuer Strahlentherapie und Radiologische Onkologie; Siewert, J.R. [Technische Univ. Muenchen (Germany). Chirurgische Klinik und Poliklinik

1995-04-21

In modern surgical oncology, adjuvant therapies are important complementary strategies. In local advanced carcinomas of the gastrointestinal tract, 5-year survival data are still disappointing despite standardized surgery. In this context, it has to be differentiated between adjuvant therapy following complete tumor exstirpation (so-called UICC R{sub 0} resection) and additive therapies following incomplete tumor resections (UICC R{sub 1} or R{sub 2} resection). Modalities in the adjuvant setting are chemotherapy, radiotherapy or the combined radio-/chemotherapy. In esophageal and gastric cancer there is up to now no benefit of postoperative adjuvant therapy. In pancreatic cancer, there are studies indicating a benefit of combined radio-/chemotherapy after complete tumor resection. A standard adjuvant chemotherapeutic treatment is proven in colon cancer stage III (Dukes C) with levamisole and 5-FU. Completely resected rectal carcinoma should be treated postoperatively with combined radio-/chemotherapy. In the common clinical or practical setting, adjuvant therapy is indicated only in locally advanced gastrointestinal tumors following R{sub 0} resection. Postoperative therapy following incomplete tumor resection has its reason only in a palliative intention. (orig.) [Deutsch] Adjuvante Therapiestrategien sind wichtige flankierende Massnahmen der modernen onkologischen Chirurgie, da u.a. die 5-Jahres-Ueberlebensquoten bei lokal fortgeschrittenen Tumoren des Gastrointestinaltraktes nach wie vor unbefriedingend sind. Dabei muss grundsaetzlich zwischen adjuvanten Behandlungen nach kompletter Tumorexstirpation (UICC-R{sub 0}-Resektion) und der additiven Therapie nach palliativer Resektion (UICC-R{sub 1}- oder -R{sub 2}-Resektion) unterschieden werden. Als Modalitaeten kommen Chemotherapie, Strahlentherapie und ihre Kombination in Frage. Bei Oesophagus- und Magenkarzinomen kann derzeit keine gueltige Empfehlung zur adjuvanten Therapie gegeben werden. Die Radio

A Fast and High-precision Orientation Algorithm for BeiDou Based on Dimensionality Reduction

Directory of Open Access Journals (Sweden)

ZHAO Jiaojiao

2015-05-01

Full Text Available A fast and high-precision orientation algorithm for BeiDou is proposed by deeply analyzing the constellation characteristics of BeiDou and GEO satellites features.With the advantage of good east-west geometry, the baseline vector candidate values were solved by the GEO satellites observations combined with the dimensionality reduction theory at first.Then, we use the ambiguity function to judge the values in order to obtain the optical baseline vector and get the wide lane integer ambiguities. On this basis, the B1 ambiguities were solved. Finally, the high-precision orientation was estimated by the determinating B1 ambiguities. This new algorithm not only can improve the ill-condition of traditional algorithm, but also can reduce the ambiguity search region to a great extent, thus calculating the integer ambiguities in a single-epoch.The algorithm is simulated by the actual BeiDou ephemeris and the result shows that the method is efficient and fast for orientation. It is capable of very high single-epoch success rate(99.31% and accurate attitude angle (the standard deviation of pitch and heading is respectively 0.07°and 0.13°in a real time and dynamic environment.

The Design of Compass/BeiDou Navigation Satellite Terminal for Migrant Bird Research

Directory of Open Access Journals (Sweden)

Yaohui Li

2014-01-01

Full Text Available A terminal of Compass Navigation Satellite System (CNSS, which can not only support BeiDou-1 and BeiDou-2 but also support Global Positioning System (GPS, is designed to research the activities of the migrant birds, with our novel design of a multiband antenna. By a high-density integration, this terminal is designed with a compact size and light weight. When the terminal is assembled to a whooper swan, its flying trace is recorded by the CNSS, which is in agreement with that of GPS. The flying route map based on the CNSS is useful to check the situation and habit of the migrant bird, which is important for animal protection and bird flu outbreak prediction.

PET/CT in lymphoma patients; PET-CT bei Lymphompatienten

Energy Technology Data Exchange (ETDEWEB)

Steinert, H.C. [Universitaetsspital Zuerich, Klinik und Poliklinik fuer Nuklearmedizin (Switzerland)

2004-11-01

First results of PET/CT in Hodgkin's disease (HD) and aggressive non-Hodgkin's lymphoma (NHL) are reported. From March 2001 to August 2004 822 PET/CT were performed at our clinic in lymphoma patients for primary staging, restaging after therapy, and diagnosis of recurrence. For coregistration non contrast-enhanced low-dose CT were used. Due to the exact anatomic localization of {sup 18}F-FDG accumulating lesions equivocal or false positive PET findings are avoided. In comparison to contrast enhanced CT, PET/CT has a higher sensitivity and specificity in patients with HD and aggressive NHL. Integration of PET/CT in treatment planning of radiation therapy optimizes the field volume. Even in the initial phase of clinical evaluation, PET/CT has proven useful in staging and restaging of lymphoma. The exact anatomic localization of the PET findings is essential for a precise report, for treatment planning of radiation therapy, and for planning surgical biopsy. (orig.) [German] Erste Ergebnisse der PET-CT bei Morbus Hodgkin (HD) und den aggressiven Non-Hodgkin-Lymphomen (NHL) werden beschrieben. Von Maerz 2001 bis August 2004 wurden 822 PET-CT bei Lymphompatienten zum primaeren Staging, zum Restaging nach Therapie und zur Rezidivdiagnostik an unserer Klinik durchgefuehrt. Fuer die Koregistration wurde ein Low-dose-CT ohne i.v.-Kontrastmittel verwendet. Durch die exakte anatomische Zuordnung der {sup 18}F-FDG aufnehmenden Laesionen wurden unklare oder falsch-positive PET-Befunde vermieden. Die PET-CT erzielte im Vergleich zur KM-verstaerkten CT eine hoehere Sensitivitaet und Spezifitaet bei Patienten mit HD und aggressiven NHL. Die Integration der PET-CT in die Planung der Strahlentherapie fuehrte zu einer Optimierung der Feldgrenzen. Die PET-CT hat sich bereits in der Phase der initialen klinischen Evaluation als wertvoll beim Staging und Restaging von Lymphomen erwiesen. Die exakte anatomische Zuordnung der PET-Informationen ist fuer eine sichere Befundung

Modified double contrast-enhanced examination of the stomach of adipose patients after vertical gastroplasty; Modifizierte Doppelkontrast-Untersuchung des Magens bei adipoesen Patienten nach vertikaler Gastroplastie

Energy Technology Data Exchange (ETDEWEB)

Raissaki, M.T. [Institut fuer Bildgebende Diagnostik, Universitaetsklinik Heraklion (Greece); Prassopoulos, P. [Institut fuer Bildgebende Diagnostik, Universitaetsklinik Heraklion (Greece); Hatjidakis, A.A. [Institut fuer Bildgebende Diagnostik, Universitaetsklinik Heraklion (Greece); Christodoulakis, M. [Klinik fuer Chirurgische Onkologie der Universitaetsklinik Heraklion (Greece); Melissas, J. [Klinik fuer Chirurgische Onkologie der Universitaetsklinik Heraklion (Greece); Gourtsoyiannis, N.C. [Institut fuer Bildgebende Diagnostik, Universitaetsklinik Heraklion (Greece)

1995-11-01

The study reported covers 28 patients who were examined once by radiology before surgery, and twice after surgery. The first post-surgery examination was done on days 5-7, the second during the 4th until 6th month after surgery. For the first examination, water-soluble contrast agent was initially applied, then barium containing contrast agent. The second examination was done by modified double contrast technique. The most frequent, pre-surgery findings revealed gastro-esophageal reflux in 13 patients. The first post-surgery control detected a somastenosis in 2 patients, while the second control examination detected complications of various nature in 11 patients and gastro-esophageal reflux in 5 patients. In 6 patients, discrepancy between clinical and radiological findings was stated. The pouch size did not correlate with the frequency of complications, or with the body-to-mass index decrease. The examination method proposed in this article yields pre-surgery information on the anatomy of the stomach, more accurate dewscription of post-surgery complications, and better evaluation of the antireflux effect of the vertical gastroplasty. (orig.) [Deutsch] In der Studie wurden 28 Patienten einmal praeoperativ und zweimal postoperativ roentgenologisch kontrolliert. Die erste postoperative Kontrolle fand am 5.-7. Tag und die zweite im 4.-6. Monat nach dem Eingriff statt. Bei der ersten Kontrolle wurde zuerst wasserloesliches und anschliessend bariumhaltiges Kontrastmittel benutzt, waehrend bei der zweiten Kontrolle eine modifizierte Doppelkontrast-Untersuchung durchgefuehrt wurde. Der haeufigste praeoperative Befund war der gastrooesophageale Reflux bei 13 Patienten. Bei der ersten praeoperativen Kontrolle fand sich bei 2 Patienten eine Stomastenose, waehrend bei der zweiten verschiedene Komplikationen bei 11 sowie gastrooesophagealer Reflux bei 5 Patienten vorlagen. Eine Diskrepanz zwischen radiologischen und klinischen Befunden fanden wir bei 6 Patienten. Die

Intra- und postoperative Komplikationen bei Patienten mit roboterassistierter laparoskopischer radikaler Prostatektomie (RALP. Eine Analyse von 3000 konsekutiven Fällen

Directory of Open Access Journals (Sweden)

Zugor V

2012-01-01

Full Text Available Einleitung: Das Ziel dieser Studie ist es, die intra- und postoperativen Komplikationen bei Patienten mit roboterassistierter laparoskopischer radikaler Prostatektomie anhand von 3000 konsekutiven Fällen aufzuzeigen. Material und Methoden:3000 Männer, welche sich einer RALP unterzogen, wurden retrospektiv untersucht. Alle Patienten wurden sowohl hinsichtlich ihrer intra- als auch postoperativen Komplikationen beobachtet. Postoperative Komplikationen und Re-Interventionen wurden bis 30 Tage nach OP erfasst und anhand der Clavien-Klassifikation in „Minor“- (Clavien-Klassifikation I–IIIa und „Major“- Komplikationen (Clavien-Klassifikation IIIb–IVa eingeteilt. Ergebnisse: Die intraoperativen Komplikationen sind ebenso wie die „minor“ und „major“ postoperativen Komplikationen in Tabellen 3 und 4 aufgeführt. Das mediane Alter der Patienten betrug 64,1 Jahre, der mediane BMI 26,7 kg/m2 , das mediane Prostatagewicht 40,1 g und der mediane PSA-Wert 10,1 ng/ml. Der Gleason-Score bei Biopsie war in 65 % kleiner als 7, in 34,4 % gleich 7 und größer als 7 in 9,6 % der Fälle. Die Lymphknotendissektion wurde in 75,9 % durchgeführt. Ein organbeschränktes Stadium zeigte sich in 75 % und eine extraprostatische Ausbreitung in 25 %. Die gesamte intraoperative Komplikationsrate lag bei 5,1 %, die „minor“ postoperative Komplikationsrate bei 16,1 % und die „major“ bei 1,8 %. Zusammenfassung: Die RALP ist nicht komplikationslos. In erfahrenen Händen ist sie jedoch ein sicheres chirurgisches Verfahren mit einer niedrigen Morbidität und Mortalität.

T-Zell-Zytokinexpression bei gestillten vs. nicht-gestillten Kindern

OpenAIRE

Aulenbach, Julia

2015-01-01

Das Bestreben, den Aufbau, die Funktion sowie die Entwicklung des Immunsystems zu verstehen, steht schon lange Zeit im Zentrum des Interesses vieler Forschungsarbeiten, insbesondere um auf Grundlage der gewonnenen Erkenntnisse neue Behandlungsansätze für immunologisch relevante Krankheitsbilder zu entwickeln. Stillen könnte ein wichtiger Faktor sein, der bei der Entwicklung und Differenzierung von T-Zell-Subpopulationen und Zytokinmustern im Säuglings- und Kindesalter eine bedeutende Roll...

Experimental study on the precise orbit determination of the BeiDou navigation satellite system.

Science.gov (United States)

He, Lina; Ge, Maorong; Wang, Jiexian; Wickert, Jens; Schuh, Harald

2013-03-01

The regional service of the Chinese BeiDou satellite navigation system is now in operation with a constellation including five Geostationary Earth Orbit satellites (GEO), five Inclined Geosynchronous Orbit (IGSO) satellites and four Medium Earth Orbit (MEO) satellites. Besides the standard positioning service with positioning accuracy of about 10 m, both precise relative positioning and precise point positioning are already demonstrated. As is well known, precise orbit and clock determination is essential in enhancing precise positioning services. To improve the satellite orbits of the BeiDou regional system, we concentrate on the impact of the tracking geometry and the involvement of MEOs, and on the effect of integer ambiguity resolution as well. About seven weeks of data collected at the BeiDou Experimental Test Service (BETS) network is employed in this experimental study. Several tracking scenarios are defined, various processing schemata are designed and carried out; and then, the estimates are compared and analyzed in detail. The results show that GEO orbits, especially the along-track component, can be significantly improved by extending the tracking network in China along longitude direction, whereas IGSOs gain more improvement if the tracking network extends in latitude. The involvement of MEOs and ambiguity-fixing also make the orbits better.

Penile angiography and superselective embolization therapy in arterial priapism; Penisangiographie und superselektive Embolisationstherapie bei high-flow Priapismus

Energy Technology Data Exchange (ETDEWEB)

Dinkel, H.P.; Triller, J. [Inst. fuer Diagnostische Radiologie, Inselspital, Univ. Bern (Switzerland); Hochreiter, W. [Urologische Klinik, Inselspital, Univ. Bern (Switzerland)

2003-08-01

Purpose: To report feasibility, benefit and complications of penile angiography and superselective penile embolization in arterial priapism. Materials and Methods: Four consecutive patients (aged 28, 29, 40 and 49 years), who underwent penile angiography for arterial priapism (high-flow priapism) within a four-year period, were identified by a keyword search of our radiology information system. One patient had sustained a direct penile trauma (severe blow to the erected penis) and three patients suffered from recurrent spontaneous priapism. All patients had previously undergone corporeal aspiration and noradrenaline injection to achieve detumescence. Two patients had one or several unsuccessful spongiocavernous shunt procedures. Results: In three of the four patients, superselective pudendal and penile angiography demonstrated pathologic arteriocavernous shunting. In two of the three patients, superselective embolization using a coaxial micro-catheter was attempted. In one of the two patients, the cavernous artery became spastic before embolization material was actually injected, inducing immediate and lasting detumescence. In the other patient, unilateral Gelfoam embolization led to immediate detumescence but the priapism recurred 12 hours after the procedure. A subsequent contralateral Gelfoam embolization was successful. Erectile function was preserved in all cases. No procedure-related complications occurred. Conclusion: Our experience supports the prevailing opinion found in the current literature that superselective coaxial embolization constitutes the treatment of choice in patients with high-flow priapism. Prognosis is good with high probability of preserving the erectile function. (orig.) [German] Ziel: Untersuchung der Interventionsmoeglichkeiten bei arteriellem (high-flow) Priapismus durch endovaskulaere superselektive Embolisation der Penisarterien. Methode: Alle innerhalb eines Vierjahreszeitraums (1/99-5/2002) wegen Priapismus zur Angiographie

Rezidivierende Endometriose bei Kinderwunsch: Operieren oder stimulieren?

Directory of Open Access Journals (Sweden)

Brunbauer M

2012-01-01

Full Text Available Kurzfassung: Endometriose ist neben dem Tubenverschluss und dem PCO-Syndrom eine der Hauptursachen für reduzierte Fertilität bei der Frau. Zur eindeutigen Diagnosesicherung ist die operative Diagnostik Standard. Eine Sanierung ist in vielen Fällen in der gleichen Sitzung möglich. Um nichts unnötig zu (zer- stören, sei die Maxime: eher weniger als mehr. Ein Rezidiv bedeutet eine weitere Reduktion der Schwangerschaftsrate. Eine Zweitoperation kann zwar Beschwerden lindern, verbessert aber die Spontan-Schwangerschaftsrate nur gering. Der Zweiteingriff ist also bezüglich der reinen Schwangerschaftsrate einer modernen IVF-Behandlung eindeutig unterlegen.

Neurofunctional MRI at high magnetic fields; Neurofunktionelle MRT bei hohen Feldern

Energy Technology Data Exchange (ETDEWEB)

Speck, O. [Fakultaet fuer Naturwissenschaften, Otto-von-Guericke Universitaet Magdeburg, Abteilung Biomedizinische Magnetresonanz, Institut fuer Experimentelle Physik, Magdeburg (Germany); Leibniz Institut fuer Neurobiologie, Magdeburg (Germany); Deutsches Zentrum fuer Neurodegenerative Erkrankungen (DZNE), Magdeburg (Germany); Center for Behavioral Brain Sciences (CBBS), Magdeburg (Germany); Turner, R. [MPI fuer Kognitions- und Neurowissenschaften, Abteilung Neurophysik, Leipzig (Germany)

2013-05-15

group data without the need for voxel-based congruence. (orig.) [German] fMRT-Untersuchungen sind durch den geringen aktivierungsinduzierten Signalunterschied in ihrer Sensitivitaet limitiert und innerhalb kurzer tolerierbarer Messzeiten ist die raeumliche Aufloesung limitiert. fMRT bei 1,5 und mehr noch bei 3 T ist ein zuverlaessiges Werkzeug in der Neurowissenschaft und fuer klinische Anwendungen, wie etwa die praechirurgische Funktionslokalisierung. Die fMRT-Sensitivitaet steigt stark (mehr als linear) mit hoeherer Magnetfeldstaerke. Dies war seit Jahren einer der Hauptgruende fuer die Entwicklung zu hoeheren Feldern wie etwa 7 T. Der Sensitivitaetsgewinn von 7 gegenueber 3 T ist bei hoher raeumlicher Aufloesung am groessten und die fMRT mit sehr hoher isotroper Submillimeteraufloesung wird moeglich. Bisherige Resultate zeigen, dass die Blood-oxygenation-level-dependent(BOLD)-Lokalisierung deutlich praeziser ist als bislang angenommen. Mittels Hochfeld-fMRT werden nicht nur quantitativ bessere Ergebnisse erzielt, sondern Informationen neuer Qualitaet zugaenglich wie etwa die kolumnare und schichtabhaengige Struktur des Kortex. Somit wird der Weg zu weiteren Informationen, wie etwa die Richtung kortikaler Verbindungen, eroeffnet. Diese Moeglichkeiten bergen jedoch auch neue Herausforderungen. So muessen neue Verfahren zur Prozessierung derart hochaufgeloester Daten entwickelt werden, welche z. B. ohne Glaettung auskommen, um den Informationsgehalt der Daten nicht zu reduzieren. Standardaufloesungen von 2-3 mm sind weiterhin bei 3 T ''gut aufgehoben'' und profitieren von geringeren Signalausloeschungen, weniger Verzerrungen und geringerer Lautstaerke. Zum Erreichen hoechster Aufloesung bei 7 T sind parallele Bildgebung und Verzerrungskorrektur essenziell und ermoeglichen eine gute Uebereinstimmung mit anatomischen Aufnahmen. Die Echozeit sollte bei 7 T auf ca. 20-25 ms angepasst und die Datenauswertung fuer einzelne Probanden oder Patienten ohne

Kombinierte Hoch-/Niedrig-Dosis-Therapie mit systemischen Glukokor-tikoiden bei schweren Verlaufsformen der Alopecia areata im Kindesalter.

Science.gov (United States)

Jahn-Bassler, Karin; Bauer, Wolfgang Michael; Karlhofer, Franz; Vossen, Matthias G; Stingl, Georg

2017-01-01

Schwere Verlaufsformen der Alopecia areata (AA) im Kindesalter sind aufgrund limitierter Optionen therapeutisch herausfordernd. Systemische, hochdosierte Glukokortikoide weisen die schnellste Ansprechrate auf, nach dem Absetzen kommt es allerdings zu Rezidiven. Eine längerfristige Hochdosis-Anwendung ist aufgrund der zu erwartenden Nebenwirkungen nicht empfehlenswert. Eine dauerhafte Steroiderhaltungstherapie unterhalb der Cushing-Schwellen-Dosis nach Bolustherapie könnte die Krankheitsaktivität ohne Nebenwirkungen längerfristig unterdrücken. Im Rahmen einer offenen Anwendungsbeobachtung wurden 13 Kinder mit schweren Formen der AA in diese Studie eingeschlossen. Bei sieben Kindern lag eine AA totalis/universalis vor, bei sechs eine multifokale AA mit Befall von mehr als 50 % der Kopfhaut. Das Therapieregime sah eine initiale Prednisolon-Dosierung von 2 mg/kg Körpergeweicht (KG) vor und wurde innerhalb von neun Wochen auf eine Erhaltungsdosierung unter der individuellen Cushing-Schwelle reduziert. Der Nachbeobachtungszeitraum betrug ein bis drei Jahre. Wir beobachteten in 62 % aller Fälle ein komplettes Nachwachsen der Haare. Die mittlere Dauer bis zum Ansprechen lag bei 6,6 Wochen und konnte mit der Erhaltungstherapie über den gesamten Beobachtungszeitraum aufrechterhalten werden. An Nebenwirkungen wurden ausschließlich eine Gewichtszunahme (1-3 kg) bei allen Behandelten sowie eine milde Steroidakne in 23 % der Fälle beobachtet. Die kombinierte Hoch-/Niedrig-Dosis-Therapie mit systemischen Glukokortikoiden mittels Prednisolon zeigte eine hohe, dauerhafte Ansprechrate ohne signifikante Nebenwirkungen. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Wie schneiden Sie ab?: Studie über Kontroll- und Prüfungsaktivitäten bei mittelgrossen Unternehmen, Spitälern und Hochschulen in der Schweiz

OpenAIRE

Ruud, T F; Isufi, S; Friebe, P; Stebler, W; Seheri, F; Emmenegger, M

2008-01-01

Kontroll- und Prüfungsaktivitäten unterstützen den Verwaltungsrat und die Geschäftsleitung bei der Steuerung und Kontrolle des Unternehmens. Bei mittelgrossen Unternehmen ist aufgrund der begrenzten personellen und finanziellen Ressourcen ein effektiver und effizienter Einsatz dieser Aktivitäten unerlässlich. Auch bei Spitälern und Hochschulen gewinnen Kontroll- und Prüfungsaktivitäten infolge erhöhter Wettbewerbsintensität und steigenden Kostendrucks sowie zunehmender Unabhängigkeit diese...

Phenol removal from wastewaters by electrochemical oxidation using boron doped diamond (BDD) and Ti/Ti{sub 0.7}Ru{sub 0.3}O{sub 2} DSA Registered-Sign electrodes

Energy Technology Data Exchange (ETDEWEB)

Britto-Costa, P.H.; Ruotolo, L.A.M., E-mail: pluis@ufscar.br [Universidade Federal de Sao Carlos (UFSCAR), SP (Brazil). Dept. de Engenharia Quimica

2012-10-15

Industrial wastewater containing non-biodegradable organic pollutants consists of highly toxic effluents whose treatment is necessary due to environmental and economical restrictions. In order to treat these effluents, an electrochemical process using a dimensionally stable anode (DSA Registered-Sign ) and boron-doped diamond (BDD) electrode was studied. The performance of these electrodes for COD removal from aqueous phenol solution was evaluated in the absence and presence of different chloride concentrations. The results showed that DSA Registered-Sign could be successfully used to remove COD when high chloride concentration (3035 mg L{sup -1}Cl{sup -}) and mild current density are employed (50 mA cm{sup -2}). On the other hand, the presence of chloride did not have the same significant effect on the COD depletion rate using BDD; however, under mild conditions (50 mA cm{sup -2}, 0.190 m s{sup -1}), the addition of 607 mg L{sup -1} Cl{sup -} improved the COD removal by approximately 52% after 8 hours of electrolysis. The effect of current density (i) and flow velocity (v) were also studied, and it was verified that they have an important role on the process performance, especially when DSA Registered-Sign is used. (author)

Aderência das Demonstrações Contábeis dos Fundos de Pensão do Brasil aos Padrões Contábeis Internacionais: Uma Análise Comparativa à Luz da IAS 26

Directory of Open Access Journals (Sweden)

Roswelton Anjos de Paula

2014-08-01

Full Text Available Apesar de o processo de convergência aos padrões internacionais provocar discussões nos vários ramos da Contabilidade, no Brasil os fundos de pensão devem observar um padrão contábil próprio, respeitando a independência patrimonial de todos os planos de benefícios dos fundos de pensão e identificando, separadamente, os planos previdenciais e assistenciais administrados pelas entidades fechadas de previdência complementar (EFPC. Com o intuito de verificar em que medida a elaboração das demonstrações contábeis das EFPC se encontra aderente aos padrões contábeis internacionais, foi efetuada uma análise comparativa entre os elementos que compõem as estruturas da Demonstração da Mutação do Ativo Líquido (DMAL, da Demonstração do Ativo Líquido (DAL e da Demonstração das Obrigações Atuariais do Plano de Benefícios (DOAP, definidas pelo padrão próprio brasileiro, e os elementos estabelecidos pela IAS 26 - Accounting and Reporting by Retirement Benefit Plans, que se aplica às demonstrações contábeis dos planos de benefícios, relatando e fornecendo informações aos participantes sobre os recursos e os benefícios do plano ao longo do tempo. Trata-se de um estudo de natureza exploratória, com abordagem qualitativa e coleta de dados realizada de forma essencialmente documental. A justificativa para o estudo está na percepção de que o desenvolvimento de um padrão próprio pode comprometer a inserção da Contabilidade dos fundos de pensão do Brasil nas melhores práticas internacionais, e inibir a participação de eventuais investidores na capitalização desses fundos. Os resultados mostram que as estruturas dos elementos que compõem as demonstrações contábeis desses fundos se encontram, em sua maior parte, aderentes ao disposto na IAS 26, sendo observadas, contudo, divergências de caráter formal nas estruturas das demonstrações contábeis e na mensuração a valor justo dos investimentos, pass

Kyphoplasty and vertebroplasty for spinal trauma; Kyphoplastie und Vertebroplastie bei Wirbelsaeulentraumata

Energy Technology Data Exchange (ETDEWEB)

Ahlhelm, F. [Kantonsspital Baden AG, Abteilung fuer Neuroradiologie, Institut fuer Radiologie, Baden (Switzerland); Omidi, R. [Kantonsspital Baden AG, Interventionelle Radiologie, Institut fuer Radiologie, Baden (Switzerland)

2016-08-15

Minimally invasive treatment of spinal fractures. Conservative treatment versus spinal surgery. Minimally invasive stabilization techniques, such as percutaneous (assisted) cementoplasty have been introduced as new procedures. Magnetic resonance imaging (MRI), X-rays and computed tomography (CT) are the imaging techniques of first choice. The most important questions concern recent fractures, instability and indications for minimally invasive treatment. Vertebroplasty and kyphoplasty are established methods for the treatment of patients with osteoporosis. Cementoplasty techniques are promising treatment options for traumatic spinal injuries. The application of the techniques should best be carried out in individual cases within the framework of prospective controlled studies. (orig.) [German] Minimal-invasive Behandlung von Wirbelsaeulentraumata. Konservative Behandlung vs. Wirbelsaeulenchirurgie. Als neue Verfahren wurden minimal-invasive Stabilisationstechniken, z. B. perkutane (assistierte) Zementoplastien eingefuehrt. Roentgen, MRT und CT sind die bildgebenden Verfahren der ersten Wahl. Die wichtigsten Fragestellungen sind: Frische Fraktur? Instabilitaet? Indikation fuer minimal-invasive Behandlung ?Vertebroplastie und Kyphoplastie sind bei Osteoporosepatienten etabliert. Bei Wirbelsaeulentraumata sind Zementoplastietechniken vielversprechende Therapieoptionen. Die Anwendung der Techniken sollte im individuellen Fall am besten im Rahmen prospektiver kontrollierter Studien erfolgen. (orig.)

Mesa redonda: Argentina en proyectos globales de investigaciones espaciales y astronómicas. Uso científico de la Antena de Espacio Profundo DSA 3

Science.gov (United States)

Colazo, M.

2016-08-01

Argentine has 10 percent of the operative time available for the DSA 3 Antenna of the European Space Agency, installed in Malargüe, Mendoza. Here we present the history of the project and the current activities for the scientific use of the antenna.

Guidelines on {sup 99m}Tc-DMSA scintigraphy in children; Empfehlungen zur Durchfuehrung der DMSA-Szintigraphie bei Kindern

Energy Technology Data Exchange (ETDEWEB)

Piepsz, A. [CHU St. Pierre, Bruessel (Belgium); Colarinha, P. [Instituto Portugues de Oncologia, Lissabon (Portugal); Gordon, I. [Great Ormend Street Hospital for Children, London (United Kingdom); Hahn, K. [Muenchen Univ. (Germany). Klinik fuer Nuklearmedizin; Olivier, P. [CHU Vandoeuvre, Nancy (France); Roca, I.; Velzen, J. van [Hospital Vall d' Hebron, Barcelona (Spain); Sixt, R. [The Queen Silvia Children' s Hospital, Goeteborg (Sweden)

2000-11-01

The guidelines are intended to help nuclear medical teams in their daily routine. The guidelines give information relating to indications, imaging parameters, data evaluation and interpretation. The guidelines are in line with the opinions of the Paediatric Committee of EANM and hence focus on approaches adopted in Europe, e.g. as regards selection of the radiopharmaceuticals or activity levels applied. The guidelines should be seen in the context of local quality standards and regulatory requirements. (orig./CB) [German] Zweck dieser Empfehlung ist es, dem Nuklearmedizinischen Team bei Tc-DMSA-Szintigraphie von Kindern Hilfestellung fuer die taegliche Routinepraxis zu geben. Die Empfehlung enthaelt Informationen ueber Indikationen, Aufnahmeparameter, Auswertung und Interpretation der DMSA-Szintigraphie bei Kindern. Die vorliegende Empfehlung fasst die Meinung des Paediatric Committee der EANM zusammen und ist daher mehr auf die Europaeische Vorgehensweise, z.B. bei der Wahl des Radiopharmazeutikums und den verwendeten Aktivitaetsmengen, ausgerichtet. Sie sollte immer in Zusammenhang mit lokalen Qualitaetsstandards und Vorschriften gesehen werden. (orig.)

Diagnostik der Fatigue bei Multipler Sklerose [Assessment of fatigue in multiple sclerosis

NARCIS (Netherlands)

Sander, C.; Voelter, H.U.; Schlake, H.P.; Eling, P.A.T.M.; Hildebrandt, H.

2017-01-01

Hintergrund: Fatigue ist eines der häufigsten Symptome bei Multipler Sklerose (MS) und hat deutliche Auswirkungen auf die Lebensqualität sowie die Berufstätigkeit. Die adäquate Messung der erlebten Fatigue ist aber auch heutzutage noch mit erheblicher Unsicherheit behaftet. Ziel der Arbeit: In dem

Criteria for choice and use of contrast media in intra-arterial D.S.A

International Nuclear Information System (INIS)

Dalla-Palma, L.; Stacul, F.; Pozzi-Mucelli, R.

1985-01-01

The authors investigated the optimal characteristics of contrast media for use in intra-arterial DSA. 209 injections in 108 patients were evaluated, most of them in the abdominal and peripheral regions. In order to decrease contrast media osmolarity and obtain an adequate mixing with blood, contrast media with low iodine concentration were injected using the same volumes and flow rates of conventional arteriography. Good results were obtained with ionic contrast media, 100 and 150 mgI/ml. depending on the area investigated. The low concentrations allowed the use of ionic agents with an osmolarity very close to that of the non ionic contrast media: the pain has been eliminated and the heat sensation reduced. Furthermore the comparison with the cost of nonionic agents shows a great saving. (orig.)

Verlauf der zellulären Immunantwort bei Lebendnierenempfängern - Messung von IFN-γ und IL-17 im Elispot-Assay

OpenAIRE

Grehn, Conrad

2015-01-01

Die Nierentransplantation ermöglicht Patienten die Wiederherstellung der Nierenfunktion. Aufgrund der begrenzten Verfügbarkeit an Organen nimmt dabei die Zahl der Transplantationen von einem lebenden Spender stetig zu. Zudem ermöglichen die präzisen und genauen Vorbereitungen und Abläufe bei Lebendnierenspenden eine bessere 5-Jahres-Überlebensrate als bei Kadaverspenden. Die genetische Verschiedenheit zwischen Spender und Empfänger bedingt jedoch eine lebenslange immunsuppressive Therapie, um...

White matter alterations in neurodegenerative and vascular dementia; Marklagerveraenderungen bei neurodegenerativen und vaskulaeren Demenzerkrankungen

Energy Technology Data Exchange (ETDEWEB)

Supprian, T. [Arbeitsgruppe Gerontopsychiatrie, Universitaets-Nervenklinik Homburg (Germany); Arbeitsgruppe Gerontopsychiatrie, Universitaets-Nervenklinik, Psychiatrie und Psychotherapie, 66421, Homburg (Germany); Kessler, H.; Falkai, P. [Arbeitsgruppe Gerontopsychiatrie, Universitaets-Nervenklinik Homburg (Germany); Retz, W.; Roesler, M. [Arbeitsgruppe Gerontopsychiatrie, Universitaets-Nervenklinik Homburg (Germany); Institut fuer gerichtliche Psychologie und Psychiatrie, Universitaet des Saarlandes, Homburg (Germany); Grunwald, I.; Reith, W. [Abteilung fuer Neuroradiologie, Universitaetskliniken des Saarlandes, Homburg (Germany)

2003-07-01

Due to a significant overlap of the two syndromes, differentiation of degenerative dementia of the Alzheimer-type from vascular dementia may be difficult even when imaging studies are available. White matter changes occur in many patients suffering from Alzheimer's disease. Little is known about the impact of white matter changes on the course and clinical presentation of Alzheimer's disease. High sensitivity of MRI in the detection of white matter alterations may account for over-diagnosing vascular dementia. The clinical significance of white matter alterations in dementia is still a matter of debate. The article reviews current concepts about the role of white matter alterations in dementia. (orig.) [German] Die Zuordnung einer Demenzerkrankung zu einem neurodegenerativen Pathomechanismus, wie der Demenz vom Alzheimer-Typ (DAT) oder einem vaskulaeren Pathomechanismus, kann trotz der Verfuegbarkeit bildgebender Verfahren Probleme bereiten. Ueberlappungen neurodegenerativer und vaskulaerer Mechanismen sind haeufig. Mikroangiopathische Veraenderungen des Marklagers finden sich bei einem hohen Anteil von Patienten mit der klinischen Verlaufsform einer Demenz vom Alzheimer-Typ. Es ist unklar, ob es sich um eine Koinzidenz zweier Pathomechanismen handelt oder ob eine wechselseitige Beeinflussung stattfindet. Die hohe Sensitivitaet der Magnetresonanztomographie bei der Erfassung mikroangiopathischer Veraenderungen des Marklagers koennte dazu fuehren, dass zu vaskulaere Demenzerkrankungen haeufig diagnostiziert werden. Der Einfluss mikroangiopathischer Veraenderungen des Marklagers auf den Demenzverlauf wird kontrovers diskutiert. Die vorgelegte Arbeit gibt eine Uebersicht ueber die aktuellen Konzepte zum Stellenwert von Marklagerveraenderungen bei Demenzerkrankungen. (orig.)

Therapeutische Überlegungen bei sensomotorischer diabetischer Neuropathie

Directory of Open Access Journals (Sweden)

Bührlen M

2013-01-01

Full Text Available Der Begriff der sensomotorischen diabetischen Neuropathie beschreibt einen heterogenen Beschwerdekomplex, der auf einer diabetesbedingten Schädigung des peripheren Nervensystems beruht. Bis zu 50 % der Menschen mit Diabetes mellitus leiden im Verlauf ihrer Erkrankung an Symptomen einer sensomotorischen Neuropathie. Chronische Schmerzen, Dysund Parästhesien sowie die Komplikation des diabetischen Fußsyndroms stellen für die Betroffenen gravierende Folgen dar. Die Optimierung der metabolischen Kontrolle stellt eine wichtige Basismaßnahme dar. Andere, zweifelsfrei gesicherte Möglichkeiten der Prävention oder kausalen Therapie sind nicht bekannt. Bei Auftreten einer schmerzhaften Neuropathie sollte eine gezielte analgetische Therapie möglichst früh begonnen werden. Mit den trizyklischen Antidepressiva, Duloxetin, Gabapentin und Pregabalin stehen Wirkstoffe zur Verfügung, die eine spezifische Therapie neuropathischer Schmerzen ermöglichen. Dabei ist zu beachten, dass in der Regel keine Schmerzfreiheit erreicht werden kann. Entscheidend ist das Erreichen eines für den Patienten tolerablen Schmerzniveaus unter Minimierung medikamentenassoziierter Nebenwirkungen. Das individuelle Ansprechen auf ein Medikament und die optimale Dosis können nicht vorhergesagt, sondern müssen individuell erprobt werden. Bei leichten Schmerzen können die Nicht-Opioid- Analgetika Paracetamol und Metamizol eingesetzt werden. Fehlen Therapiealternativen, dann stellen Opioide eine weitere Möglichkeit der Therapie starker Schmerzen dar. Aufgrund einer zusätzlichen Monoamin-Wiederaufnahmehemmerwirkung nehmen Tramadol und Tapentadol in dieser Gruppe eine Sonderstellung ein. In der Risiko- Nutzen-Abwägung darf das Nebenwirkungs- und Abhängigkeitspotenzial der Opioide in der Langzeittherapie nicht unterschätzt werden. Für andere medikamentöse Therapien oder alternative Therapiemethoden liegt keine ausreichende wissenschaftliche Evidenz vor. Sie können aber im

Taxonomia de distorções contábeis

OpenAIRE

José Humberto da Cruz Cunha; Rogério Henrique de Araújo Júnior

2017-01-01

http://dx.doi.org/10.5007/1518-2924.2017v22n49p127 Discute o uso de uma taxonomia de distorções contábeis provenientes de erros e fraudes, voltada para o uso dos auditores na análise dos riscos e escolha dos procedimentos de auditoria. Sua elaboração segue as orientações conceituais da classificação facetada, por meio de levantamento conceitual em pesquisa bibliográfica. A taxonomia apresentada possui como categorias fundamentais as fases da informação, aspectos essenciais, afirmações, ci...

Diagnostic evaluatuin of gastrointestinal tumors; Diagnostik bei Tumoren im Gastrointestinaltrakt

Energy Technology Data Exchange (ETDEWEB)

Linke, R.; Tatsch, K. [Ludwig-Maximilians-Univ. Muenchen (Germany). Klinik und Poliklinik fuer Nuklearmedizin

1998-07-01

difficult to distinguish between chronic pancreatitis and pancreatic carcinoma. In such cases a PET scan may be helpful. For planning of surgery and for preoperative staging morphological imaging is essential, but in nearly 40% of the patients nonresectable tumors were detected intraoperatively, which were not diagnosed by preoperative CT or MRI. PET seems to be more accurate in this respect, too. (orig.) [Deutsch] Hauptaufgaben der radiologischen und nuklearmedizinischen Diagnostik bei gastrointestinalen Tumoren sind Diagnosesicherung sowie praeoperatives Staging. Die Hohlorgane des oberen und unteren GI-Traktes (Oesophagus, Magen, Duodenum, Kolon, Rektum) werden primaer endoskopisch und endosonographisch abgeklaert. CT oder MRT liefern Informationen ueber Ausdehnung des Tumors, eine Infiltration in umgebende Strukturen und das Vorliegen pathologischer Lymphknoten. Das sensitivste Verfahren zum Nachweis von Lymphknoten- oder Fernmetastasen ist die PET. Auch die Differenzierung eines Lokalrezidivs von postoperativer Narbenbildung, z.B. beim kolorektalen Karzinom, gelingt mit der PET fruehzeitiger als mit den konventionellen morphologischen Verfahren. Lebertumoren sollten primaer sonographisch und bei fraglicher Dignitaet anschliessend mittels MRT untersucht werden. In der Differentialdiagnostik von unklaren Leberherden ist die nuklearmedizinische Rezeptorszintigraphie wegweisend. Benigne Leberlaesionen koennen mit der Neogalaktoalbumin-(NGA-)Szintigraphie sicher von malignen Tumoren (Metastasen, hepatozellulaeres Karzinom [HCC]) abgegrenzt werden, da NGA-Rezeptoren nur auf funktionstuechtigen Hepatozyten experimentiert werden. Die Unterscheidung von Lebermetastasen und dem HCC gelingt mit der Insulinszintigraphie, da sich Insulin aufgrund einer Ueberexpression von Insulinrezeptoren mit HCC vermehrt anreichert. Ergeben die vorgeschalteten Untersuchungen den Verdacht auf einen malignen Prozess, sollte zusaetzlich eine CT-Arterioportographie durchgefuehrt werden, da dieses

Radiotherapy of heterotopic bone formation in patients with paraplegia. Preliminary results; Strahlentherapie heterotoper Ossifikationen bei Querschnittsgelaehmten. Praeliminaere Ergebnisse

Energy Technology Data Exchange (ETDEWEB)

Sautter-Bihl, M.L. [Klinik fuer Strahlentherapie, Staedtisches Klinikum Karlsruhe (Germany); Liebermeister, E. [Klinik fuer Strahlentherapie, Staedtisches Klinikum Karlsruhe (Germany); Heinze, H.G. [Klinik fuer Strahlentherapie, Staedtisches Klinikum Karlsruhe (Germany); Nanassy, A. [Klinik fuer Orthopaedie, Rehabilitationskrankenhaus Langensteinbach (Germany); Stoltze, D. [Klinik fuer Orthopaedie, Rehabilitationskrankenhaus Langensteinbach (Germany)

1995-08-01

In 20 patients with paralysis, 25 regions were irradiated with (mostly) 10 Gy in single fractions of 2 to 2.5 Gy using 8 MW photons. In 15 patients radiotherapy was performed as a primary treatment in the status of myositis; 7 patients were treated after (subtotal) resection of already manifest ossifications (2 patients were treated twice, primarily and postoperatively). In a minimum follow-up 12 weeks, none of the 20 irradiated patients showed any progression of the developing or already manifest ossification; thus mobilisation and rehabilitation could be carried out as desired. No side effects occurred. The preliminary results of the present study suggest that radiotherapy is an effective local treatment with minimal side effects for the prevention of heterotopic bone formation in patients with paraplegia. (orig.) [Deutsch] Bei 20 Patienten (18 Maenner, zwei Frauen, Alter 19 bis 62 Jahre) mit Querschnittssyndrom wurden 25 Regionen mit ueberwiegend 10 Gy a 2 bis 2,5 Gy Einzeldosis mit 8-MW-Photonen bestrahlt. Die Radiatio erfolgte bei 15 Patienten als Primaerprophylaxe im entzuendlichen Stadium, bei sieben Patienten sekundaer nach (subtotaler) Resektion von Ossifikationen (zwei Patienten wurden sowohl primaer als auch sekundaer bestrahlt). Bei einer Mindestnachbeobachtungszeit von zwoelf Wochen trat in keinem Fall eine Progression der sich entwickelnden bzw. bereits bestehenden heterotopen Ossifikationen auf: saemtliche Patienten konnten wunschgemaess mobilisiert und im Rahmen ihrer neurologischen Ausfaelle rehabilitiert werden. Nebenwirkungen traten nicht auf. Die vorliegende praeliminaeren Ergebnisse deuten hin, dass die Strahlentherapie eine effektive und nebenwirkungsarme lokale Therapie zur Verhinderung heterotoper Ossifikationen beim Querschnittssyndrom darstellt. (orig.)

MR arthrography of the shoulder: possible indications for clinical use; Einsatzmoeglichkeiten der MR-Arthrographie bei Erkrankungen des Schultergelenkes

Energy Technology Data Exchange (ETDEWEB)

Kreitner, K.F. [Mainz Univ. (Germany). Klinik mit Poliklinik fuer Radiologie; Grebe, P. [Mainz Univ. (Germany). Klinik mit Poliklinik fuer Radiologie; Kersjes, W. [Mainz Univ. (Germany). Klinik mit Poliklinik fuer Radiologie; Runkel, M. [Mainz Univ. (Germany). Klinik fuer Unfallchirurgie; Kirschner, P. [Elisabeth-Hospital, Mainz (Germany). Abt. fuer Unfall- und Wiederherstellungschirurgie St. Vincenz; Schild, H.H. [Mainz Univ. (Germany). Klinik mit Poliklinik fuer Radiologie

1994-02-01

In a prospective study possible indications for MR arthrography of the shoulder were evaluated. 37 patients were examined before and after intraarticular administration of a 2-mmolar solution of Gd-DTPA. MR arthrography was performed if there was no joint effusion and/or an uncertain finding concerning the rotator cuff or the capsulolabral complex on plain MR images. MR arthrography leads to a better demonstration of labrum pathology in 11/22 patients and to a superior delineation of the capsuloligamentous apparatus in 20/22 cases. In 9/15 patients with impingement lesions MR arthrography allowed a differentiation of severe tendinitis from partial and small full-thickness tears of the rotator cuff. MR arthrography of the shoulder joint enhances the accuracy of MR in case of an uncertain finding on plain MR images. (orig.) [Deutsch] In einer prospektiven Studie sollten Einsatzmoeglichkeiten der MR-Arthrographie bei Erkrankungen des Schultergelenkes herausgearbeitet werden. 37 Patienten wurden sowohl nativ als auch nach intraartikulaerer Gabe einer 2mmolaren Gd-DTPA-Loesung untersucht. Voraussetzungen fuer die KM-Gabe waren ein fehlender Gelenkerguss und/oder ein unklarer Befund des Labrum-Kapsel-Komplexes oder der Rotatorenmanschette in der Nativuntersuchung. Durch die MR-Arthrographie wurde bei 11/22 Patienten eine verbesserte Darstellung der Labrumpathologie erzielt; in 20/22 Faellen ergabe sich eine zuverlaessige Beurteilung der Gelenkkapsel. Bei 9/15 Patienten mit Erkrankungen der Rotatorenmanschette konnten Tendinitiden von partiellen und kleinen kompletten Rotatorenmanschettenrupturen sicher differenziert werden. Die MR-Arthrographie des Schultergelenkes fuehrt bei nicht eindeutigen Befunden in der Nativuntersuchung zu einer verbesserten Treffsicherheit der MR-Diagnostik. (orig.)

The operative cooperation and nursing in performing airway stent placement under DSA guidance for treating airway stenosis

International Nuclear Information System (INIS)

Yan Baojun; Wu Gang; Han Xinwei; Wang Nan; Shi Jin; Si Wenfeng; Wang Kai; Su Ning; Liu Jia; Hai Dandan

2011-01-01

Objective: To discuss the key points of the nursing care for effectively performing airway stent placement under DSA monitoring for airway stenosis. Methods: Corresponding nursing care measures were carried out for 118 patients with airway stenosis who were treated with airway stent placement. Results: The symptom of dyspnea was markedly relieved after stent implantation in all 118 patients with airway stenosis. Conclusion: To strengthen the preoperative psychological nursing and operative posture training, to make close postoperative watch on vital signs, to adopt some prevention measures for possible complications and to give necessary medical advises at the time of discharge are very helpful for patient's recovery after the surgery. (authors)

F-18-FDG PET of the thyroid in Graves` disease; F-18-FDG-PET der Schilddruese bei Morbus Basedow

Energy Technology Data Exchange (ETDEWEB)

Boerner, A.R.; Voth, E.; Schicha, H. [Klinik und Poliklinik fuer Nuklearmedizin, Koeln Univ. (Germany); Wienhard, K.; Wagner, R. [Max-Planck-Institut fuer Neurologische Forschung, Koeln (Germany)

1998-12-31

This study evaluates F-18-FDG PET of the thyroid in Graves` disease. Methods: Thirty patients were investigated the day before radioiodine therapy, 15 patients 3-10 days after radioiodine therapy. Twenty patients with cancer of the head or neck and normal thyroid function served as controls. Results: F-18-FDG uptake was higher in Graves` disease patients than in controls. Negative correlations of F-18-FDG uptake with half-life of radioiodine and absorbed radiation dose due to radioiodine therapy were found along with a positive correlation to autoantibody levels. Conclusion: Thus F-18-FDG PET is likely to give information on the biological activity of Graves` disease as well as on early radiation effects. (orig.) [Deutsch] Ziel: Diese Studie evaluiert F-18-Fluoro-Deoxy-Glukose (F-18-FDG) PET der Schilddruese bei Patienten mit M. Basedow. Methoden: 30 Patienten wurden am Tag vor Radioiod-Therapie, 15 Patienten am 3.-10. Tag nach Radioiodtherapie untersucht. 20 Patienten mit Kopf/Halstumoren und normaler Schilddruesenfunktion dienten als Kontrollgruppe. Ergebnisse: Die F-18-FDG-Aufnahme in der Schilddruese war signifikant hoeher bei Patienten mit M-Basedow im Vergleich zu den Kontrollen. Sie stieg mit hoeheren, antithyreoidalen Antikoerpern und sank bei laengerer I-131-Halbwertzeit. Es bestand eine Korrelation einer reduzierten Glukose-Utilisation bei hoeherer absorbierter Schilddruesendosis nach Radioiod-Therapie. Schlussfolgerung: Damit erscheint die F-18-FDG-PET-Untersuchung zur biologischen Aktivitaetsbeurteilung des M. Basedow und Darstellung von fruehen Strahleneffekten geeignet. (orig.)

Prognostic value of cardiovascular MRI in diabetics; Prognostischer Wert der kardiovaskulaeren MRT bei Diabetikern

Energy Technology Data Exchange (ETDEWEB)

Schlett, C.L.; Bertheau, R.C.; Kauczor, H.U.; Weckbach, S. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany)

2015-04-01

Risikostratifizierung von Noeten ist. Die klinische Untersuchung und die Bestimmung von Blutwerten dienen bei Diabetikern typischerweise zur Risikostratifizierung bzgl. kardio(zerebro)vaskulaerer Ereignisse in der Zukunft. Sowohl die Kardio- als auch die Ganzkoerper-MRT stellen standardisierte Verfahren in der klinischen Diagnostik dar. Deren Stellenwert bei der Vorhersage von Ereignissen mit entsprechender Risikostratifizierung bei Diabetikern gewinnt basierend auf aktuellen Studienergebnissen zunehmend an Bedeutung. Late Gadolinium Enhancement (LGE) im Kardio-MRT detektiert bei bis zu 30 % der Diabetiker stumme Myokardischaemien, die mit einer Hazard Ratio von 3-6 mit kardiovaskulaeren Ereignissen assoziiert sind. Ebenfalls zeigen linksventrikulaere Wandbewegungsstoerungen sowie eine erniedrigte Ejektionsfraktion einen prognostischen Wert. Im Ganzkoerper-MRT sind der Vessel-Score und Karotisstenosen zusaetzliche Praediktoren fuer kardio(zerebro)vaskulaere Ereignisse. Die MRT-basierte Vorhersage kardio(zerebro)vaskulaerer Ereignisse bietet einen signifikanten Mehrwert zur klassischen Risikostratifizierung bei Diabetikern. Jedoch erlaubt nur die umfassende Ganzkoerper-MRT-Untersuchung Patienten zu identifizieren, die ueber einen Zeitraum von 6 Jahren komplett frei von kardio(zerebro)vaskulaeren Ereignissen bleiben. Die Kardio-MRT, insbesondere die Erfassung von LGE, empfiehlt sich fuer die Vorhersage von Ereignissen. Die Ganzkoerper-MRT stellt einen prognostischen Mehrwert dar, deren klinische Relevanz in weiteren Studien geklaert werden muss. (orig.)

Comparative imaging study in ultrasound, MRI, CT, and DSA using a multimodality renal artery phantom

Energy Technology Data Exchange (ETDEWEB)

King, Deirdre M.; Fagan, Andrew J.; Moran, Carmel M.; Browne, Jacinta E. [Medical Ultrasound Physics and Technology Group, School of Physics, Dublin Institute of Technology, Dublin 8 (Ireland); Centre for Advanced Medical Imaging (CAMI), St James' s Hospital, Dublin 8 (Ireland); Department of Medical Physics, University of Edinburgh, Edinburgh EH16 4TJ (United Kingdom); Medical Ultrasound Physics and Technology Group, School of Physics, Dublin Institute of Technology, Dublin 8 (Ireland)

2011-02-15

Purpose: A range of anatomically realistic multimodality renal artery phantoms consisting of vessels with varying degrees of stenosis was developed and evaluated using four imaging techniques currently used to detect renal artery stenosis (RAS). The spatial resolution required to visualize vascular geometry and the velocity detection performance required to adequately characterize blood flow in patients suffering from RAS are currently ill-defined, with the result that no one imaging modality has emerged as a gold standard technique for screening for this disease. Methods: The phantoms, which contained a range of stenosis values (0%, 30%, 50%, 70%, and 85%), were designed for use with ultrasound, magnetic resonance imaging, x-ray computed tomography, and x-ray digital subtraction angiography. The construction materials used were optimized with respect to their ultrasonic speed of sound and attenuation coefficient, MR relaxometry (T{sub 1},T{sub 2}) properties, and Hounsfield number/x-ray attenuation coefficient, with a design capable of tolerating high-pressure pulsatile flow. Fiducial targets, incorporated into the phantoms to allow for registration of images among modalities, were chosen to minimize geometric distortions. Results: High quality distortion-free images of the phantoms with good contrast between vessel lumen, fiducial markers, and background tissue to visualize all stenoses were obtained with each modality. Quantitative assessments of the grade of stenosis revealed significant discrepancies between modalities, with each underestimating the stenosis severity for the higher-stenosed phantoms (70% and 85%) by up to 14%, with the greatest discrepancy attributable to DSA. Conclusions: The design and construction of a range of anatomically realistic renal artery phantoms containing varying degrees of stenosis is described. Images obtained using the main four diagnostic techniques used to detect RAS were free from artifacts and exhibited adequate contrast

Comparative imaging study in ultrasound, MRI, CT, and DSA using a multimodality renal artery phantom

International Nuclear Information System (INIS)

King, Deirdre M.; Fagan, Andrew J.; Moran, Carmel M.; Browne, Jacinta E.

2011-01-01

Purpose: A range of anatomically realistic multimodality renal artery phantoms consisting of vessels with varying degrees of stenosis was developed and evaluated using four imaging techniques currently used to detect renal artery stenosis (RAS). The spatial resolution required to visualize vascular geometry and the velocity detection performance required to adequately characterize blood flow in patients suffering from RAS are currently ill-defined, with the result that no one imaging modality has emerged as a gold standard technique for screening for this disease. Methods: The phantoms, which contained a range of stenosis values (0%, 30%, 50%, 70%, and 85%), were designed for use with ultrasound, magnetic resonance imaging, x-ray computed tomography, and x-ray digital subtraction angiography. The construction materials used were optimized with respect to their ultrasonic speed of sound and attenuation coefficient, MR relaxometry (T 1 ,T 2 ) properties, and Hounsfield number/x-ray attenuation coefficient, with a design capable of tolerating high-pressure pulsatile flow. Fiducial targets, incorporated into the phantoms to allow for registration of images among modalities, were chosen to minimize geometric distortions. Results: High quality distortion-free images of the phantoms with good contrast between vessel lumen, fiducial markers, and background tissue to visualize all stenoses were obtained with each modality. Quantitative assessments of the grade of stenosis revealed significant discrepancies between modalities, with each underestimating the stenosis severity for the higher-stenosed phantoms (70% and 85%) by up to 14%, with the greatest discrepancy attributable to DSA. Conclusions: The design and construction of a range of anatomically realistic renal artery phantoms containing varying degrees of stenosis is described. Images obtained using the main four diagnostic techniques used to detect RAS were free from artifacts and exhibited adequate contrast to allow

Antigranulocyte scintigraphy of septic loosening of hip prosthesis: influence of different analyzing methods; Antigranulozytenszintigraphie bei septischer Hueft-Endoprothesen-Lockerung: Einfluss unterschiedlicher Auswertemethoden

Energy Technology Data Exchange (ETDEWEB)

Klett, R.; Steiner, D.; Puille, M.; Khalisi, A.; Bauer, R. [Giessen Univ. (Germany). Klinik fuer Nuklearmedizin; Matter, H.P.; Stuerz, H. [Giessen Univ. (Germany). Orthopaedische Klinik

2001-06-01

Diagnosis of infection with help of antigranulocyte scintigraphy near body stem is difficult because of contemporary visualisation of bone marrow. Therefore, we investigated, whether it is possible to improve the accuracy in diagnosing septic loosening of hip endoprosthesis by changing the analyzing methods. Methods: In 28 patients, the results of a visual interpretation of late scan, a visual interpretation and a quantitative interpretation of time-activity-course were compared. These results were verified by histology respectively microbiology. Results: Histological and microbiological verification found 14 septic loosening and 14 aseptic loosening of the hip protheses. Therefore, sensitivity, specificity, negative and positive predictive value for the visual interpretation of late scan were 0.86, 0.57, 0.80 and 0.67. For visual and quantitative interpretation of time-activity-course we found 0.86, 0.79, 0.85 and 0.80 respectively 1, 0.93, 1, 0.93. For interobserver agreement we found kappa coefficients of 0.28 {+-} 0.2 for visual interpretation of late scan, 0.48 {+-} 0.17 for visual interpretation and 1.0 {+-} 0 for quantitative interpretation of time-activity-course. Conclusion: In all investigated values quantitative interpretation of time-activity-course was superior to the other analyzing methods. Therefore, antigranulocyte scintigraphy for septic loosening of hip endoprosthesis should be interpreted quantitatively. (orig.) [German] Bei der Entzuendungsdiagnostik mittels Antigranulozytenszintigraphie ergeben sich in der Naehe des Koerperstammes aufgrund der gleichzeitigen Knochenmarkdarstellung Beurteilungsschwierigkeiten, da nicht immer sicher zwischen entzuendlichen Fokus beziehungsweise Knochenmark zu unterscheiden ist. Es wurde daher untersucht, ob bei der Diagnostik der septischen Hueft-Endoprothesen-Lockerung durch Aenderung des Auswerteverfahrens eine Verbesserung der Aussage zu erzielen ist. Methode: Bei 28 Patienten wurden die Ergebnisse einer

Umgang mit Antithrombotika bei Operationen an der Haut vor und nach Publikation der entsprechenden S3-Leitlinie.

Science.gov (United States)

Gaskins, Matthew; Dittmann, Martin; Eisert, Lisa; Werner, Ricardo Niklas; Dressler, Corinna; Löser, Christoph; Nast, Alexander

2018-03-01

Laut einer Befragung im Jahre 2012 war der Umgang mit Antithrombotika bei dermatochirurgischen Eingriffen in Deutschland sehr heterogen. 2014 wurde erstmals eine evidenzbasierte Leitlinie zu diesem Thema veröffentlicht. Es wurde eine anonyme Befragung derselben Stichprobe zum Umgang mit Antithrombotika sowie zu Kenntnissen der Leitlinie durchgeführt. Die Ergebnisse wurden als relative Häufigkeiten berichtet und denen aus 2012 gegenübergestellt. 208 Antwortbögen wurden ausgewertet (Rücklaufquote: 36,6 %). Die große Mehrheit der Dermatologen erklärte, kleinere Eingriffe unter Fortführung der Therapie mit Phenprocoumon, niedrig dosierter Acetylsalicylsäure (≤ 100 mg) und Clopidogrel sowie mit direkten oralen Antikoagulanzien durchzuführen. Bei größeren Eingriffen war der Umgang hingegen weiterhin heterogen, insbesondere unter niedergelassenen Dermatologen. Der Anteil der Dermatologen, die Phenprocoumon, Acetylsalicylsäure und Clopidogrel leitlinienkonform verwendeten, hat sich insgesamt vergrößert. Führten 2012 beispielsweise 53,8 % der Klinikärzte bzw. 36,3 % der niedergelassenen Dermatologen eine große Exzision unter Fortführung der Therapie mit niedrig dosierter Acetylsalicylsäure durch, taten dies 2017 90,2 % bzw. 57,8 % (Phenprocoumon: 33,8 % bzw. 11,9 % auf 63,9 % bzw. 29,9 %; Clopidogrel: 36,9 % bzw. 23,2 % auf 63,9 % bzw. 30,6 %). Unter den Klinikärzten war ein hoher Anteil mit der Leitlinie vertraut und fand diese hilfreich. Eine Zunahme des leitlinienkonformen Verhaltens war bei allen Eingriffen zu verzeichnen. Bei größeren Eingriffen zeigte sich trotz deutlicher Verbesserung die Notwendigkeit verstärkter Anstrengungen zur Leitlinienumsetzung bzw. zur Identifizierung von Implementierungsbarrieren. © 2018 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Erkrankungen des Traumaspektrums bei ruandischen Waisen des Genozids : Epidemiologie und Behandlung

OpenAIRE

Schaal, Susanne

2006-01-01

Im Jahre 1994 kamen in Ruanda innerhalb von 100 Tagen fast eine Million Menschen auf brutalste Weise ums Leben. Vorliegende Studie untersuchte die Traumakonfrontation und mentalen Gesundheitseffekte dieses staatlich organisierten Genozids bei ruandischen Waisen (n = 118) 11 Jahre nach dem Völkermord. Die Stichprobe setzte sich aus Vollwaisen zusammen, die entweder in kindergeführten Haushalten oder in Waisenheimen der Hauptstadt Kigali lebten. Risikofaktoren wurden analysiert und die Wirksamk...

Craniocerebral trauma. Magnetic resonance imaging of diffuse axonal injury; Schaedel-Hirn-Trauma. MRT bei diffuser axonaler Verletzung

Energy Technology Data Exchange (ETDEWEB)

Mallouhi, A. [Medizinische Universitaet Wien, Allgemeines Krankenhaus, Abteilung fuer Neuro- und Muskuloskelettale Radiologie, Klinik fuer Radiologie und Nuklearmedizin, Wien (Austria)

2014-09-15

Acceleration-deceleration rotational brain trauma is a common cause of disability or death in young adults and often leads to a focal destruction of axons. The resulting pathology, axonal shear injury is referred to as diffuse axonal injury (DAI). The DAI-associated lesions occur bilaterally, are widely dispersed and have been observed in the surface and deep white matter. They are found near to and far from the impact site. When DAI is clinically suspected, magnetic resonance imaging (MRI) is the method of choice for further clarification, especially in patients where cranial computed tomography (CT) is inconspicuous. To investigate the presence of DAI after traumatic brain injury (TBI), a multimodal MRI approach is applied including the common structural and also functional imaging sequences. For structural MRI, fluid-attenuated inversion recovery (FLAIR) weighted and susceptibility contrast imaging (SWI) are the sequences mainly used. The SWI technique is extremely sensitive to blood breakdown products, which appear as small signal voids at three locations, at the gray-white interface, in the corpus callosum and in the brain stem. Functional MRI comprises a group of constantly developing techniques that have great potential in optimal evaluation of the white matter in patients after craniocerebral trauma. These imaging techniques allow the visualization of changes associated with shear injuries, such as functional impairment of axons and decreased blood flow and abnormal metabolic activity of the brain parts affected. The multimodal MRI approach in patients with DAI results in a more detailed and differentiated representation of the underlying pathophysiological changes of the injured nerve tracts and helps to improve the diagnostic and prognostic accuracy of MRI. When DAI is suspected multimodal MRI should be performed as soon as possible after craniocerebral injury. (orig.) [German] Das Rotationstrauma des Gehirns ist bei jungen Erwachsenen ein haeufiger Grund

Berechnung verkehrlicher Substitutionseffekte im Personenverkehr bei Online-Shopping

Science.gov (United States)

Nerlich, Mark R.; Schiffner, Felix; Vogt, Walter; Rauh, Jürgen; Breidenbach, Petra

Für Güter des täglichen, mittelfristigen und langfristigen Bedarfs sowie für das Beispiel Baumarktartikel wird das Potenzial für Personenverkehrsaufwand von Einkaufsaktivtäten quantitativ abgeschätzt. Die entwickelten Algorithmen behandeln die einkaufsvorbereitende Information und den eigentlichen Einkauf, d.h. den Erwerb eines Gutes, separat. Informationsaktivitäten haben insbesondere bei höherwertigen Gütern einen hohen Stellenwert und damit auch verkehrliche Relevanz. Wie Berechnungen zeigen, spart Online-Shopping Informations- und Einkaufsverkehrsaufwand im Pkw-Verkehr ein. Die notwendigen Eingangsdaten wie differenzierte Informations- und Einkaufshäufigkeiten sowie verkehrliche Parameter zu Verkehrsmittelwahl, Entfernungen und Wegekopplungen wurden aus eigenen Erhebungen gewonnen.

Application of the DSA preconditioned GMRES formalism to the method of characteristics - First results

International Nuclear Information System (INIS)

Le Tellier, R.; Hebert, A.

2004-01-01

The method of characteristics is well known for its slow convergence; consequently, as it is often done for SN methods, the Generalized Minimal Residual approach (GMRES) has been investigated for its practical implementation and its high reliability. GMRES is one of the most effective Krylov iterative methods to solve large linear systems. Moreover, the system has been 'left preconditioned' with the Algebraic Collapsing Acceleration (ACA) a variant of the Diffusion Synthetic Acceleration (DSA) based on I. Suslov's former works. This paper presents the first numerical results of these methods in 2D geometries with material discontinuities. Indeed, previous investigations have shown a degraded effectiveness of Diffusion Synthetic Accelerations with this kind of geometries. Results are presented for 9 x 9 Cartesian assemblies in terms of the speed of convergence of the inner iterations (fixed source) of the method of characteristics. It shows a significant improvement on the convergence rate. (authors)

Psychologie körperlicher Aktivität bei Patienten mit Rückenschmerzen

OpenAIRE

Leonhardt, Corinna

2008-01-01

Die vorliegende Arbeit setzt sich mit den psychologischen Determinanten und Fördermöglichkeiten von körperlicher Aktivität bei Rückenschmerzpatienten auseinander, wobei Daten einer multizentrischen cluster-randomisierten Studie (N= 1378) genutzt werden. Der theoretische Hintergrund aller Originalarbeiten gibt einen Überblick zu neuen Erkenntnissen zum Rückenschmerz und zur Aktivitätsförderung in der Gesundheitspsychologie und ...

High-precision GNSS ocean positioning with BeiDou short-message communication

Science.gov (United States)

Li, Bofeng; Zhang, Zhiteng; Zang, Nan; Wang, Siyao

2018-04-01

The current popular GNSS RTK technique would be not applicable on ocean due to the limited communication access for transmitting differential corrections. A new technique is proposed for high-precision ocean RTK, referred to as ORTK, where the corrections are transmitted by employing the function of BeiDou satellite short-message communication (SMC). To overcome the limitation of narrow bandwidth of BeiDou SMC, a new strategy of simplifying and encoding corrections is proposed instead of standard differential corrections, which reduces the single-epoch corrections from more than 1000 to less than 300 bytes. To solve the problems of correction delays, cycle slips, blunders and abnormal epochs over ultra-long baseline ORTK, a series of powerful algorithms were designed at the user-end software for achieving the stable and precise kinematic solutions on far ocean applications. The results from two long baselines of 240 and 420 km and real ocean experiments reveal that the kinematic solutions with horizontal accuracy of 5 cm and vertical accuracy of better than 15 cm are achievable by convergence time of 3-10 min. Compared to commercial ocean PPP with satellite telecommunication, ORTK is of much cheaper expense, higher accuracy and shorter convergence. It will be very prospective in many location-based ocean services.

Análise da relação entre as informações contábeis e o risco sistemático no mercado brasileiro

Directory of Open Access Journals (Sweden)

Ana Luísa Gambi Cavallari Amorim

2012-12-01

Full Text Available De acordo com a literatura existente, as informações contábeis representam um importante estimador dos fluxos de caixa futuros da empresa, servindo, portanto, para fins de avaliação do risco de um investimento em ações. Isso porque tais informações refletem a realidade econômico-financeira da empresa em um dado período, possuindo, consequentemente, relação com o risco sistemático de um investimento, o que justifica sua utilização para fins de decisões relacionadas à composição de um portfólio de ações. Dentro desse contexto, o presente trabalho busca apresentar evidências empíricas da relação entre as informações contábeis e o risco sistemático no mercado brasileiro. Mais especificamente, objetiva-se analisar a relação entre os betas contábeis e os betas de mercado de companhias no Brasil. Para isso, foram selecionadas 97 empresas, da Bolsa de Valores, Mercadorias e Futuros de São Paulo (BM&FBOVESPA, de 15 setores econômicos, entre o 1º trimestre de 1995 e o 3º trimestre de 2009. Foram utilizadas 468 variáveis contábeis. Para operacionalizar a relação entre as variáveis foi utilizado um modelo de regressão com dados em painel. Os resultados evidenciaram que alguns betas contábeis podem explicar o beta de mercado e podem fazê-lo de forma antecipada, podendo, ainda, melhorar a previsão do beta de mercado quando associados a betas de mercado históricos. Por outro lado, a maior parte das versões de betas contábeis apresentou relação pouco significativa ou mesmo inexistente.

Hyperonenproduktion in C+C- und Si+Si-Kollisionen bei 158 GeV pro Nukleon

CERN Document Server

Kraus, Ingrid

2004-01-01

Ultrarelativistische Schwerionenstöße werden seit etwa 15 Jahren untersucht, um Kernmaterie unter extremen Bedingungen zu erforschen; in Kollisionen schwerer Atomkerne kann bei hohen Einschußenergien Kernmaterie stark komprimiert und aufgeheizt werden. Die Bedeutung dieser Experimente wird durch Berechnungen der Quanten-Chromo-Dynamik auf raumzeitlichen Gittern hervorgehoben, die bei ausreichend hoher Energiedichte eine Phase voraussagen, in der die Quarks nicht mehr in Hadronen gebunden sind, sondern zusammen mit den Gluonen ein partonisches System ausbilden. Ist das System hinreichend groß und equilibriert, wird es als Quark-Gluon-Plasma bezeichnet. Die als Signatur für das Überschreiten der Phasengrenze vorgeschlagene erhöhte Produktion Seltsamkeit tragender Teilchen wurde in der Gegenüberstellung von elementaren Proton+Proton-Interaktionen und Kern+Kern-Stößen experimentell über einen weiten Energiebereich bestätigt. Eine solche Überhöhung kann aber auch durch rein hadronische Phänomene her...

Transdermales Testosterongel verbessert die Parameter Sexualfunktion, Stimmung, Muskelkraft und Körperzusammensetzung bei hypogonadalen Männern

Directory of Open Access Journals (Sweden)

Wang C

2003-01-01

Full Text Available Eine Testosterontherapie bei hypogonadalen Männern sollte die klinisch manifesten Symptome eines Testosteronmangels im Sinne der Verbesserung der Sexualfunktion, der Vermehrung der Muskelmasse und -kraft sowie der Verringerung des Körperfettanteils korrigieren, ohne gleichzeitig nennenswerte Nebenwirkungen hervorzurufen. Wir haben bereits gezeigt, daß die Verabreichung eines neuen transdermalen Testosterongels an Männer mit Hypogonadismus zu dosisabhängigen Erhöhungen des Serumtestosteronspiegels in den Normalbereich erwachsener Männer führt. Wir berichten nun über die Auswirkungen einer 6-monatigen Behandlung mit diesem 1 %igen Testosterongel (50 bzw. 100 mg Testosteron pro Tag, enthalten in 5 bzw. 10 g Gel im Vergleich zu einem Penetrationsvermittler enthaltenden Testosteronpflaster (5 mg/Tag auf bestimmte Wirksamkeitsparameter bei 227 Männern mit Hypogonadismus. In den mit Testosterongel behandelten Gruppen wurde die Dosis am Studientag 90 auf 75 mg/Tag (enthalten in 7,5 g Gel erhöht oder gesenkt, wenn die Serumtestosteronspiegel über oder unter dem Normalbereich für erwachsene Männer lagen. In der Gruppe mit Testosteronpflaster wurde keine Dosisanpassung vorgenommen. Die Sexualfunktion und Stimmungsveränderungen wurden anhand eines Fragebogens, die Körperzusammensetzung anhand der DEXA-Methode und die Muskelkraft mit einer speziellen Technik("one repetitive maximum technique" durch Pressen der Beine und Arme ermittelt. Sexualfunktion und Stimmung verbesserten sich bereits am Tag 30 der Behandlung maximal, ohne Unterschied zwischen den Gruppen, und zeigten bei Fortsetzung der Therapie keine weitere Besserung. Die mittlere Muskelkraft bei der Beinpreßübung erhöhte sich in allen Gruppen nach 90 Behandlungstagen um 11 bis 13 kg und verbesserte sich anschließend bis zum Ende der Behandlung am Tag 180 nicht weiter. Zu mäßigen Steigerungen der Kraftentwicklung kam es auch an der Schulter- und Armmuskulatur. Nach 90 Tagen

Cytoprotection with amifostine in the simultaneous radio-chemotherapy of recurrent head and neck cancer; Zytoprotection mit Amifostin im Rahmen der Radiochemotherapie bei vorbestrahlten Kopf-Hals-Karzinomen

Energy Technology Data Exchange (ETDEWEB)

Buentzel, J.; Weinaug, R.; Kuettner, K. [Zentralklinikum gGmbH Suedthueringen, Suhl (Germany). Klinik fuer Hals-Nasen-Ohren-Heilkunde, Plastische Operationen; Glatzel, M.; Froehlich, D. [Zentralklinikum gGmbH Suedthueringen, Suhl (Germany). Klinik fuer Strahlentherapie; Schuth, J. [Essex Pharma, Muenchen (Germany)

1999-11-01

Purpose: The radiotherapeutic possibilities are limited for patients with a recurrent or second head and neck cancer if the patient was already irradiated in the first therapy. In the presented study we investigated the changes of this situation due to the usage of amifostine in the case of re-irradiation (simultaneous radio-chemotherapy). Patients and methods: Between 1995 and 1997 we treated 14 patients with a recurrent or second malignancy of the head and neck region by a simultaneous radio-chemotherapy (20x1.5 Gy, Carboplatin 70 mg/m{sup 2} BSA on days 1 to 5 and 16 to 20, 500 mg amifostine prior to every carboplatin infusion). Six out of 14 patients got an additional brachytherapy (10 to 15 Gy) to increase the local dose because of a residual tomor. In 4 cases the treatment was an adjunctive one, following the surgical tumor debulking. Results: We have seen 3 complete remissions (21.4%), and 8 partial remissions (57.1%). The median time of observation in 13 months now. Three out of 14 patients died, 2 because of the tumor. Hematological toxicities: Side effects Grade 2 WHO were seen only in 1 patient. Acute non-hematological toxicities: Mucositis Grade 0/1 in 7 patients, mucositis Grade 2 in 7 patients, dysphagia Grade 0/1 in 9 patients, dysphagia Grade 2 in 5 patients, xerostomia Grade 1 in 9 patients, xerostomia Grade 2 in 3 patients. We registrated only 1 serious late toxicity due to radio-chemotherapy: 4 months after brachytherapy a patient (with laryngectomy) developed a submental fistula. Conclusion: These first results suggest that the usage of amifostine offers new potential ways for re-irradiation of patients with recurrent or second malignancies in the head neck region. (orig.) [German] Ziel: Bei einem Rezidiv- oder Zweitkarzinom im Kopf-Hals-Bereich sind die radiotherapeutischen Moeglichkeiten bei bereits vorbestrahlten Patienten sehr begrenzt. Inwieweit die Integration des selektiven Zytoprotektivums Amifostin in eine nochmalige Radiochemotherapie

Pediatric radiological diagnostics in suspected child abuse; Kinderradiologische Diagnostik bei Verdacht auf Kindesmisshandlung

Energy Technology Data Exchange (ETDEWEB)

Erfurt, C.; Schmidt, U. [Technische Universitaet Dresden, Institut fuer Rechtsmedizin, Medizinische Fakultaet, Dresden (Germany); Hahn, G. [Universitaetsklinikum Carl Gustav Carus, Dresden, Abteilung Kinderradiologie, Institut und Poliklinik fuer Radiologische Diagnostik, Dresden (Germany); Roesner, D. [Universitaetsklinikum Carl Gustav Carus, Dresden, Klinik und Poliklinik fuer Kinderchirurgie, Dresden (Germany)

2009-10-15

Advanced and specialized radiological diagnostics are essential in the case of clinical suspicion of pediatric injuries to the head, thorax, abdomen, and extremities when there is no case history or when ''battered child syndrome'' is assumed on the basis of inadequate trauma. In particular, the aim of this sophisticated diagnostic procedure is the detection of lesions of the central nervous system (CNS) in order to initiate prompt medical treatment. If diagnostic imaging shows typical findings of child abuse, accurate documented evidence of the diagnostic results is required to prevent further endangerment of the child's welfare. (orig.) [German] Klinisch diagnostizierte Verletzungen an Kopf, Thorax, Abdomen oder Extremitaeten eines Kindes bei scheinbar leerer Anamnese oder Angabe eines inadaequaten Traumas erfordern beim Verdacht auf ein Battered-Child-Syndrom eine erweiterte und spezialisierte radiologische Diagnostik. Diese soll insbesondere im Bereich des ZNS Verletzungsfolgen erfassen, um therapeutische Massnahmen einleiten zu koennen. Bei typischen, auf eine Misshandlung hinweisenden radiologischen Befunden ist eine praezise beweissichere Befunddokumentation erforderlich, um eine weitere Kindeswohlgefaehrdung zu vermeiden. (orig.)

A comparabilidade das escolhas contábeis na mensuração subsequente de ativos imobilizados, de ativos intangíveis e de propriedades para investimento

OpenAIRE

Souza, Flaida êmine Alves de

2014-01-01

A expertise comparabilidade, escolhas contábeis e valor justo é um dos temas mais controvertidos e carentes de discussões no cenário contábil atual. As escolhas contábeis são necessárias para que seja garantida a representação fidedigna, ao mesmo tempo em que seu uso discricionário pode diminuir a comparabilidade, que é esperada pelo IASB. Quando as escolhas contábeis se referem à opção entre os métodos do custo histórico e do valor justo, as controvérsias são ainda maiores. Em decorrência di...

Instrumentos para determinação do índice de evidenciação de informações contábeis

Directory of Open Access Journals (Sweden)

Ilse Maria Beuren

2015-04-01

Full Text Available Este estudo descreve as características de instrumentos citados na literatura para apuração do índice de evidenciação de informações contábeis. Pesquisa descritiva foi realizada por meio de análise documental, com abordagem qualitativa. Os resultados focalizam cinco temáticas que exprimem os cuidados necessários ao elaborar uma métrica de mensuração de evidenciação de informações contábeis: público-alvo e definição de informação coercitiva e voluntária; escolha da base de dados; extensão do instrumento de coleta de dados; fatores que interferem na métrica; e testes de confiabilidade. O estudo pode contribuir na identificação de métricas para mensurar a extensão da evidenciação de informações contábeis pelas empresas.

Paradoxical effects of radioiodine therapy in functional thyroid autonomy and mild immunothyropathy; Paradoxe Effekte der Radiojodtherapie bei funktioneller Schilddruesenautonomie und milder Immunthyreopathie

Energy Technology Data Exchange (ETDEWEB)

Dunkelmann, S.; Rudolph, F.; Prillwitz, A.; Groth, P.; Schuemichen, C. [Rostock Univ. (Germany). Klinik und Poliklinik fuer Nuklearmedizin

1998-01-01

Aim: To examine all cases with Graves` disease after radioiodine therapy of autonomously functioning thyroid tissue (AFFT) in order to find the cause. Methods: We retrospectively studied 1428 pts who were treated between 11/93 and 3/97 with radioiodine for AFTT and who underwent at least one control examination. Results: 15 (1.1%) of all pts developed Graves` disease 8.4 (4-13) months after radioiodine therapy. There was no direct suggestion of Graves` disease (TRAK negative, no endocrine ophthalmopathy) in any pt at the time of radioiodine therapy. More detailed analysis of anamnestic data, however, revealed evidence that immunothyropathy predated radioiodine therapy in 11 of the 15 pts. Paradoxical effects of radioiodine therapy manifested as an increase in immunothyropathy 14 pts, a deterioration in metabolism in 11 pts and a first occurrence of endocrine ophthalmopathy in 5 pts. Conclusion: Exacerbation of preexisting, functional primarily insignificant immunothyropathia is held responsible in most cases for the observed paradoxical effects after radioiodine therapy, resulting in radiation-induced manifest Graves` disease; however no therapeutical consequences are recommended. (orig.) [Deutsch] Ziel: Erfassung von Pat. mit einer nach Radiojodtherapie wegen einer funktionellen Autonomie aufgetretenen Immunhyperthyreose sowie deren Ursachen. Methoden: Wir untersuchten in einer retrospektiven Studie 1428 Pat., die im Zeitraum 11/93 bis 3/97 wegen einer funktionellen Autonomie mit Radiojod behandelt wurden und die sich mindestens einer Kontrolluntersuchung unterzogen hatten. Ergebnisse: 15 (1,1%) der Pat. entwickelten 8,4 (4-13) Monate nach Radiojodtherapie eine postradiogene Immunhyperthyreose. Bei allen 15 Pat. lag zum Zeitpunkt der Radiojodtherapie kein direkter Hinweis auf eine Immunhyperthyreose vor (TRAK neg., keine endokrine Orbitopathie). Bei einer genauen Analyse anamnestischer Daten fanden sich jedoch bei 11 der 15 Pat. erste Hinweise auf das Vorliegen

Wirksamkeit und Verträglichkeit von Mepartricin (Iperplasin® bei benigner Prostatahyperplasie: Ergebnisse eine Anwendungsbeobachtung

Directory of Open Access Journals (Sweden)

Madersbacher H

2000-01-01

Full Text Available Ziel der Studie: Das Ziel dieser Anwendungsbeobachtung war es, Wirksamkeit und Verträglichkeit von Mepartricin-Filmtabletten (Iperplasin® bei der Behandlung von Patienten mit benigner Prostatahyperplasie (BPH bzw. Prostatavergrößerung (BPE zu untersuchen. Patienten und Methoden: Im Rahmen einer österreichweiten Anwendungsbeobachtung wurden Patienten mit unterer Harntraktsymptomatik (LUTS, verursacht durch eine BPH/BPE, untersucht. Die wichtigsten Einschlußkriterien waren eine reduzierte maximale Harnflußrate (Qmax von 6-15 ml/sec und ein Restharn 100 ml. Als Studienmedikation erhielten die Patienten 3 x 1 Tbl. Iperplasin®. Ein, drei und sechs Monate nach Studienbeginn wurden die Patienten nachkontrolliert. Die wichtigsten Zielparameter waren eine Verbesserung des Internationalen Prostata Symptomen Scores (IPSS, der Lebensqualitätsfrage des IPSS (IPSS-Ql sowie des Qmax. Ein Einfluß auf die Sexualität wurde anhand des GRISS-Scores erhoben. Ergebnisse: Insgesamt wurden 130 Patienten (67,4 ± 8,4 Jahre; Durchschnitt ± Standardabweichung in diese Studie aufgenommen. Der IPSS sank von 16,4 ± 5,0 zu Studienbeginn auf 9,4 ± 6,0 (-41 %; p 0,0001 nach 6 Monaten Therapie, der IPSS-Ql von 3,3 ± 0,8 auf 2,0 ± 1,1 (-39 %; p 0,0001. Im gleichen Zeitraum stieg der Qmax von 11,3 ± 6,0 auf 12,5 ± 6,4 ml/sec (+11 %; p 0,0001, der Restharn sank von 49 ± 36 ml auf 33 ± 35 ml (-33 %; p 0,0001. Insgesamt war die Therapie mit Iperplasin® gut verträglich, bei 10 % traten im Rahmen der Studie unerwünschte Ereignisse oder interkurrente Erkrankungen auf, bei zwei Patienten mußte eine TURP durchgeführt werden. Der GRISS-Score blieb über den gesamten Studienzeitraum konstant. Schlußfolgerung: Diese Anwendungsbeobachtung belegt die Sicherheit von Iperplasin® bei Patienten mit LUTS und BPH/BPE, vor allem kommt zu keiner Beeinträchtigung der Vita sexualis. Obwohl eine signifikante Verbesserung von subjektiven und objektiven Parametern in dieser

MRI in cardiac sarcoidosis and amyloidosis; MRT bei kardialer Sarkoidose und Amyloidose

Energy Technology Data Exchange (ETDEWEB)

Bauner, K.U. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany); Wintersperger, B. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany); University of Toronto, Department of Medical Imaging, Toronto General Hospital, Toronto, ON (Canada)

2013-01-15

Sarcoidosis and amyloidosis are both multisystem disorders, which may involve the heart; however, isolated cardiac disease is rare. Diagnosis of cardiac sarcoidosis and amyloidosis is crucial because the patient prognosis is dependent on cardiac involvement and early treatment. Echocardiography is the first line imaging modality in the diagnostic work-up of both diseases, possibly giving hints towards the correct diagnosis. Besides myocardial biopsy and radionuclide studies cardiac magnetic resonance imaging (MRI) is routinely performed in patients suspect of having infiltrative cardiomyopathy. The T1 mapping procedure is currently being evaluated as a new technique for detection and quantification of global myocardial enhancement, as seen in cardiac amyloidosis. Sensitivities and specificities for detection of cardiac sarcoidosis and amyloidosis can be significantly improved by MRI, especially with late gadolinium enhancement (LGE) imaging. In cardiac sarcoidosis the use of LGE is outcome-related while in amyloidosis analysis of T1-mapping may be of prognostic value. If cardiac involvement in sarcoidosis or amyloidosis is suspected cardiac MRI including LGE should be performed for establishing the diagnosis. (orig.) [German] Die Sarkoidose und Amyloidose sind Multisystemerkrankungen, in deren Verlauf es zu einer kardialen Beteiligung kommen kann. Bildgebend wird als primaeres Verfahren die Echokardiographie eingesetzt. Zur weiteren Diagnostik wird neben der Biopsie und nuklearmedizinischen Verfahren v. a. die MRT herangezogen. Als neuere Technik zur Darstellung globaler diffuser Kontrastmittelanreicherungen, wie sie im Rahmen der Amyloidose vorkommen, wird z. Z. das T1-Mapping evaluiert. Durch den Einsatz der MRT, insbesondere des Late-Gadolinium-Enhancements (LGE), koennen die Sensitivitaet und Spezifitaet in der Diagnostik der kardialen Sarkoidose und Amyloidose entscheidend verbessert werden. Bei der Sarkoidose stellt das Vorhandensein eines LGE einen

Somatostatin receptor scintigraphy in endocrine ophthalmopathy; Somatostatin-Rezeptor-Szintigraphie bei endokriner Orbitopathie

Energy Technology Data Exchange (ETDEWEB)

Diaz, M. [Klinik und Poliklinik fuer Nuklearmedizin, Univ. Mainz (Germany); Kahaly, G. [3. Medizinische Klinik und Poliklinik, Innere Medizin - Endokrinologie, Univ. Mainz (Germany); Muehlbach, A. [3. Medizinische Klinik und Poliklinik, Innere Medizin - Endokrinologie, Univ. Mainz (Germany); Bockisch, A. [Klinik und Poliklinik fuer Nuklearmedizin, Univ. Mainz (Germany); Beyer, J. [3. Medizinische Klinik und Poliklinik, Innere Medizin - Endokrinologie, Univ. Mainz (Germany); Hahn, K. [Klinik und Poliklinik fuer Nuklearmedizin, Univ. Mainz (Germany)

1994-12-01

Somatostatin receptor scintigraphy with {sup 111}In-labeled octreotide proves to be a very sensitive diagnostic tool for evaluation of inflammative activity in endocrine ophthalmopathy (EO). The results of somatostatin receptor scintigraphy (SRS) in 40 patients with EO show a high orbital accumulation of {sup 111}In-octreotide in clinically active EO (4h-median/orbit-brain-ratio: 12.6; controls 4h-median: 5.8) Patients with clinically inactive EO (4h-median: 7.1) show a similar orbital accumulation of radioactivity compared to controls. 5 patients with active orbital myositis also revealed an even higher orbital accumulation of radioactivity (4h-median: 42.3). The diagnostic value of SRS lies in its ability to act as a measure of inflammation and an be useful as an activity parameter when planning therapeutic procedure as well as for EO follow-up. The results in patients with orbital myositis nevertheless do not permit a differential diagnosis with this method. The therapeutic value of {sup 111}In-octreotide in Graves` disease has yet to be established. (orig.) [Deutsch] Die Somatostatin-Rezeptor-Szintigraphie (SRS) mit dem {sup 111}Indium-markierten Somatostatinanalogon Octreotid stellt ein sensitives Verfahren zur Einschaetzung der entzuendlichen Aktivitaet bei endokriner Orbitopathie (EO) dar. Die Untersuchungen an 40 Patienten mit EO ergaben eine im Vergleich zur Kontrollgruppe signifikant hoehere orbitale Octreotidanreicherung bei klinisch aktiver Erkrankung (4h-Median/Orbita-Hirn-Quotient: 12,6; Kontrollgruppe 4h-Median: 5,8; p=0,0032). Patienten mit klinisch nicht aktiver Erkrankung (4h-Median: 7,1) unterschieden sich bezueglich der orbitalen Octreotidanreicherung nicht wesentlich von der Kontrollgruppe. Auch 5 Patienten mit florider orbitaler Myositis zeigten eine deutlich gesteigerte orbitale Aktivitaetsanreicherung (4h-Median: 42,3). Der diagnostische Nutzen der SRS liegt somit in ihrer Eigenschaft als Aktivitaets- und Entzuendungsparameter und kann mit

The MR imaging and DSA features and embolization therapy of spinal dural arteriovenous fistulae

International Nuclear Information System (INIS)

Zhang Hua; Hu Jinqing; Lin Dong; Wu Daming; Wang Dengbin; Yang Yanmin; Cheng Kemin

2005-01-01

Objective: To investigate the MR imaging and DSA features together with endovascular embolization of spinal dural arteriovenous fistulae (SDAVF). Methods: Twelve patients with SDAVF underwent both MR imaging and angiography of spinal cord, 4 of them received endovascular embolization. The imaging findings of MRI and angiography in all patients were analyzed. Results: Among 12 cases with SDAVF, 11 cases showed diffuse long T 2 signal, 2 cases demonstrated inhomogeneous maculate enhancement in the spinal cord and 6 cases revealed abnormal vessels in the dorsal spaces of spinal cord on MRI. Angiography of spinal cord showed orifices of all fistulae, draining veins, the extent of lesions, amount of feeding vessels and the angiographic features in all the 12 cases. 4 cases with embolization treatment showed improvement clinically. Conclusions: Angiography of spinal cord is the main method and MRI provides important assistance for diagnosing SDAVF while endovascular embolization is an effective method for the treatment. (authors)

Characterization of arterial stenosis using 3D imaging: comparison between three imaging techniques (MRA, spiral CTA and 3D DSA) and four display methods (MIP, SR, MPVR, VA) in a phantom study

International Nuclear Information System (INIS)

Bendib, K.; Poirier, C.; Croisille, P.; Roux, J.P.; Devel, D.; Amiel, M.

1999-01-01

Introduction: accurate assessment of arterial stenosis is a major public health issue for the diagnosis and treatment of cardiovascular diseases. The number of imaging techniques and types of software for display of imaging data is increasing. Few studies that compare these different techniques are available in the literature. Materials and methods: using phantoms to reproduce the main types of arterial stenosis, the authors compared three 3D acquisition techniques (MRA, CTA, and 3D DSA) and four types of display methods (MIP, SR, MPVR, and VA). The degree, the shape, and the location of different types of stenoses were analyzed by three experienced observers during two successive readings. Intra- and inter-observer reproducibility were assessed. The results of the various acquisition techniques and display methods also were compared to the digital reference data (CFAO) of the physical phantoms. Results: the degree of intra- and inter-observer reproducibility for the assessment of shape and location of the stenoses was good. Visual assessment of the degree of stenosis showed significant differences between two observers as well as in two readings by one observer. The 3D DSA was the most accurate technique for assessing the degree of stenosis. CTA provided better results than MRA. MPVR provided an accurate assessment of the degree of the stenosis. 3D DSA and CTA assessed stenosis form and localization adequately, with no significant difference; both methods appeared to be more accurate than MRA. SR provided the best information on the eccentric nature of the stenosis. The shape was very well assessed by VA and MPVR. Conclusions: even though 3D DSA is the most accurate acquisition technique for visualization, the combined use of SR and MPVR appears to be the best compromise to describe the morphology and degree of stenosis. Further improvements in automatic 3D image processing could offer a better understanding and increased possibilities for assessing arterial

PET in patients with clear-cut multiple chemical sensitivity (MCS); PET bei Patienten mit klar definierter multipler chemischer Sensibilitaet (MCS)

Energy Technology Data Exchange (ETDEWEB)

Bornschein, S. [Toxikologische Abt. der II. Medizinischen Klinik und Poliklinik der Technischen Univ. Muenchen, Klinikum rechts der Isar, Muenchen (Germany); Klinik und Poliklinik fuer Psychiatrie und Psychotherapie der Technischen Univ. Muenchen, Klinikum rechts der Isar, Muenchen (Germany); Hausteiner, C.; Foerstl, H. [Klinik und Poliklinik fuer Psychiatrie und Psychotherapie der Technischen Univ. Muenchen, Klinikum rechts der Isar, Muenchen (Germany); Drzezga, A.; Schwaiger, M. [Nuklearmedizinische Klinik und Poliklinik der Technischen Univ. Muenchen, Klinikum rechts der Isar, Muenchen (Germany); Bartenstein, P. [Klinik und Poliklinik fuer Nuklearmedizin, Universitaetsklinikum Mainz (Germany); Zilker, Th. [Toxikologische Abt. der II. Medizinischen Klinik und Poliklinik der Technischen Univ. Muenchen, Klinikum rechts der Isar, Muenchen (Germany)

2002-12-01

Aim: Multiple chemical sensitivity (MCS) is a controversially discussed symptom complex. Patients afflicted by MCS react to very low and generally non-toxic concentrations of environmental chemicals. It has been suggested that MCS leads to neurotoxic damage or neuroimmunological alteration in the brain detectable by positron emission tomography (PET) and single photon emission computer tomography (SPECT). These methods are often applied to MCS patients for diagnosis, although they never proved appropriate. Method: We scanned 12 MCS patients with PET, hypothesizing that it would reveal abnormal findings. Results: Mild glucose hypometabolism was present in one patient. In comparison with normal controls, the patient group showed no significant functional brain changes. Conclusion: This first systematic PET study in MCS patients revealed no hint of neurotoxic or neuroimmunological brain changes of functional significance. (orig.) [German] Ziel: Multiple chemische sensibilitaet (MCS) ist ein umstrittenes Krankheitsbild, das durch Reaktionen auf geringe, fueer Normalpersonen unschaedliche Mengen an Umweltchemikalien gekennzeichnet ist. Es wurde postuliert, dass MCS zu neurotoxischer Schaedigung bzw. neuroimmunologischer Veraenderung im Gehirn fuehrt, die mittels funktioneller bildgebender Verfahren, z. B. positronenemissionstomographie (PET), single-photon-emissions-computer-tomographie (SPECT) dargestellt werden koennte. Obwohl hierfuer kein wissenschaftlicher Beleg erbracht wurde, werden diese Methoden vielfach diagnostisch bei MCS-Patienten eingesetzt. Methode: Wir untersuchten 12 MCS-Patienten mit PET, um etwaige funktionelle Hirnveraenderungen nachzuweisen. Ergebnisse: Im Einzelvergleich war bei einem Patienten ein diskreter Glukose-Hypometabolismus in einzelnen Hirnregionen vorhanden. Im Gruppenvergleich konnte keine signifikante Abweichung von der Norm gefunden werden. Schlussfolgerung: Diese erste systematische PET-Studie bei MCS-Patienten erbrachte keinen

Shortcomings of the industrial quality assurance of {sup 106}Ru ophthalmic plaques; Therapierelevante Schwachstellen bei der industriellen Qualitaetssicherung von {sup 106}Ru-Augenapplikatoren

Energy Technology Data Exchange (ETDEWEB)

Kaulich, T.W.; Nuesslin, F. [Universitaetsklinik fuer Radioonkologie, Tuebingen (Germany). Abt. Medizinische Physik; Zurheide, J. [BrainLAB AG, Heimstetten (Germany); Fluehs, D. [Abt. Strahlentherapie, Bereich klinische Strahlenphysik, Universitaetsklinikum Essen (Germany); Haug, T. [Isotopenlabor der Univ. Tuebingen (Germany); Bamberg, M. [Abt. Radioonkologie, Universitaetsklinik fuer Radioonkologie, Tuebingen (Germany)

2001-11-01

Background: Beta emitting {sup 106}Ru applicators manufactured by Bebig GmbH (Berlin, Germany) are widely used to treat intraocular tumors. The applicators are fixed to the bulbus and removed after several days. The following therapy relevant defects have been detected by an internal clinical acceptance test: risk of leakage and inconsistent dose-rate specifications by the manufacturer. In the meantime, components of the internal clinical acceptance test have been adopted successfully by the manufacturer of the {sup 106}Ru ophthalmic plaques. Material and Method: {sup 106}Ru ophthalmic plaques were tested with the following internal clinical acceptance tests: visual inspection, surface contamination, leakage, and dose-rate verification. The surface contamination test consists of a wet wipe test at moderate pressure. For the leakage test of the {sup 106}Ru ophthalmic plaques a clinically relevant scenario was developed in which the contact of the applicator with human tissue is simulated. In the course of it the applicator is inserted into Ringer's solution for several days. The certified energy dose-rate statements of the manufacturer are examined with a 1 mm{sup 3} plastic scintillator for consistency. (orig.) [German] Hintergrund: {sup 106}Ru-Augenapplikatoren der Fa. Bebig (Berlin) werden zur strahlentherapeutischen Behandlung von intraokularen Tumoren eingesetzt. Die Applikatoren werden sklerakontaktierend am Bulbus fixiert und nach mehreren Tagen wieder entfernt. Durch eine klinikinterne Eingangspruefung wurden folgende therapierelevante Maengel bei den Augenapplikatoren entdeckt: mangelhafte Dichtheit und inkonsistente Dosisleistungsangaben des Herstellers. Ein Teil dieser klinikinternen Eingangspruefung wurde inzwischen vom Hersteller der {sup 106}Ru-Augenapplikatoren uebernommen und erfolgreich eingesetzt. Material und Methode: Es wurden {sup 106}Ru-Augenapplikatoren durch folgende klinikinterne Eingangspruefungen getestet: optische Inspektion

An automated computerized methodology for the segmentation of in vivo acquired DSA images: application in the New Zealand hindlimb ischemia model

International Nuclear Information System (INIS)

Kagadis, G C; Daskalakis, A; Spyridonos, P; Nikiforidis, G C; Diamantopoulos, A; Samaras, N; Katsanos, K; Karnabatidis, D; Siablis, D; Sourgiadaki, E; Cavouras, D

2009-01-01

In-vivo dynamic visualization and accurate quantification of vascular networks is a prerequisite of crucial importance in both therapeutic angiogenesis and tumor anti-angiogenesis studies. A user independent computerized tool was developed, for the automated segmentation and quantitative assessment of in-vivo acquired DSA images. Automatic vessel assessment was performed employing the concept of image structural tensor. Initially, vasculature was estimated according to the largest eigenvalue of the structural tensor. The resulted eigenvalue matrix was treated as gray-matrix from which the vessels were gradually segmented and then categorized in three main sub-groups; large, medium and small-size vessels. The histogram percentiles, corresponding to 85%, 65% and 47% of prime eigenvalue gray-matrix were optimally found to give the thresholds T1, T2 and T3 respectively, for extracting vessels of different size. The proposed methodology was tested on a series of DSA images in both normal rabbits (group A) and in rabbits with experimental induced chronic hindlimb ischemia (group B). As a result an automated computerized tool was developed to process images without any user intervention in either experimental or clinical studies. Specifically, a higher total vascular area and length were calculated in group B compared to group A (p=0.0242 and p=0.0322 respectively), which is in accordance to the fact that significantly more collateral arteries are developed during the physiological response to the stimuli of ischemia.

Determinanten der beruflichen Belastung bei jungen Lehrerinnen und Lehrern: Eine Längsschnittstudie

OpenAIRE

Candova, Antonia

2005-01-01

In der vorliegenden Arbeit wird geprüft, ob berufliche Belastung bei jungen Lehrerinnen und Lehrern von Personenmerkmalen (Top-down-Ansatz), Umweltmerkmalen (Bottom-up-Ansatz) und/oder der Interaktion zwischen Merkmalen der Person und Situation beeinflusst wird. Die Daten stammen aus der prospektiven Längsschnittsstudie "Berufsverläufe in der Mathematik", die sich mit der beruflichen Entwicklung von Mathematikabsolvierenden (Diplom und Lehramt) befasst. Hier werden Daten von 266 aktuell beruf...

Electrochemical degradation of reactive dyes at different DSA compositions

Energy Technology Data Exchange (ETDEWEB)

Silva, Rodrigo G. da; Aquino Neto, Sydney; Andrade, Adalgisa R. de, E-mail: ardandra@ffclrp.usp.b [Universidade de Sao Paulo (FFCLRP/USP), Ribeirao Preto, SP (Brazil). Fac. de Filosofia Ciencias e Letras. Dept. de Quimica

2011-07-01

This paper investigates the electrochemical oxidation of the reactive dyes reactive blue 4 (RB-4) and reactive orange 16 (RO-16) on RuO{sub 2} dimensionally stable anode (DSA) electrodes. Electrolysis was achieved under galvanostatic control as a function of supporting electrolyte and electrode composition. The electrolyses, performed in either the presence or absence of NaCl, were able to promote efficient color removal; moreover, at low chloride concentration (0.01 mol L{sup -1}), total color removal was obtained after just 10 min of electrolysis, and a significant increase in total dye combustion was achieved for all the studied anodes in chloride medium (reaching ca. 80% - chemical oxygen demand - COD removal). No significant enhancement in dye color removal or mineralization was observed upon increasing chloride concentration. The influence of oxide composition on dye elimination seems to be significant in both media (with or without chloride), being Ti/Ru{sub 0.30}Ti{sub 0.70}O{sub 2}, the most active material for organic compound oxidation. The oxygen evolution reaction was shown to be a limiting reaction in both supporting electrolytes; i.e., NaCl and Na{sub 2}SO{sub 4}, and its competition with organic compound oxidation remained an obstacle. The adsorbable organo halogens formation study revealed that there is slight consumption of the undesirable species formed within the first minutes of the electrolysis, being Ti/(RuO{sub 2}){sub 0.70}(Ta{sub 2}O{sub 5}){sub 0.30} the most environmentally friendly composition. Both anode composition and chloride concentration affect the formation of these undesirable compounds. (author)

MRI in dementia-type diseases; MRT bei demenziellen Erkrankungen

Energy Technology Data Exchange (ETDEWEB)

Bodea, S.V.; Muehl-Benninghaus, R. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg (Germany)

2015-05-01

Dementia-inducing conditions represent a leading cause of disability and are a major health concern in industrialized countries. The burden these conditions put on society is certain to rise in the context of an ever-increasing elderly population. As these conditions feature an insidious onset and overlapping clinical features, imaging is a powerful tool in refining the diagnosis and assessing the progression of dementing conditions. The radiologist needs to be aware of and be able to detect underlying pathologies which could be reversible. Furthermore, imaging is important not only in excluding other pathologies but also in improving diagnostic accuracy. This article presents the typical clinical presentations as well as magnetic resonance imaging (MRI) features of the degenerative and the non-degenerative causes of dementia. The focus is on the core knowledge for MRI diagnostics in dementing conditions and a brief presentation of the latest MRI techniques which may become a part of standard imaging protocols in the future. (orig.) [German] Demenzielle Erkrankungen gehoeren in den Industrielaendern zu den haeufigsten Ursachen fuer Beeintraechtigungen im Alltag. Durch eine stetig alternde Population nimmt auch die Belastung fuer die Gesellschaft immer weiter zu. Bei haeufig schleichendem Symptombeginn sowie sich ueberlappender Klinik mit anderen Krankeitsbildern kann die Bildgebung ein gutes Werkzeug zur Praezisierung der Diagnose und Beurteilung eines Progresses sein. Der Radiologe sollte andere und reversible Pathologien erkennen und von demenztypischen Veraenderungen abgrenzen koennen. Dieser Artikel beschreibt typische klinische Symptome und auch bildmorphologische Veraenderungen verschiedener Demenzformen, die durch neurodegenerative und nichtdegenerative Ursachen bedingt sein koennen. Ausserdem werden aktuellste MRT-Techniken vorgestellt. Diese koennten kuenftig im Standartprotokoll zur Bildgebung bei der Abklaerung demenzieller Syndrome verankert sein. (orig.)

Exact measurement of vascular lumina in digital subtraction arteriography (DSA) during stent implantations and percutaneous transluminal angioplasty (PTA)

Energy Technology Data Exchange (ETDEWEB)

Pfluger, T [Dept. of Radiology, Univ. of Munich (Germany); Kueffer, G [Dept. of Radiology, Univ. of Munich (Germany); Hahn, D [Dept. of Radiology, Univ. of Munich (Germany)

1992-06-01

There are inherent difficulties in using high-resolution DSA in interventional radiology for measuring vascular luminal diameter since enlargement ratios are not constant. We present a system that permits accurate determination of vascular lumen diameters by means of a special angiographic catheter with predefined marking points. The accuracy of this measuring method was explored in tests using phantoms. In vivo practicability of the method was proved in PTA and stent implantations in 39 patients. This method with a maximum error of measurement of 5% appears to provide adequate safety in the choice of suitable dilating balloons and stents in interventional vascular procedures. In follow-up, it permits the accurate measurement of neo-intimal thickness. (orig.)

MR volumetry of the trigeminal nerve in patients with unilateral facial pain; MR-Volumetrie des N. trigeminus bei Patienten mit einseitigen Gesichtsschmerzen

Energy Technology Data Exchange (ETDEWEB)

Kress, B.; Fiebach, J.; Sartor, K.; Stippich, C. [Abt. Neuroradiologie, Neurologische Klinik, Universitaetsklinikum Heidelberg (Germany); Rasche, D.; Tronnier, V. [Neurochirurgische Klinik, Universitaetsklinikum Heidelberg (Germany)

2004-05-01

Purpose: to assess whether MRI can detect atrophy of the trigeminal nerve in patients with trigeminal neuralgia. Materials and methods: a prospective MRI study was conducted in 39 patients (trigeminal neuralgia, trigeminal neuropathy, or atypical facial pain) and 25 volunteers. Using a coronal orientation (T1 flash 3D; T2 CISS 3D), regions of interest were delineated in the cisternal part of the trigeminal nerve along the border of the nerve to calculate the volume of the nerve. The volume of the nerve was compared side-by-side in each patient (t-test, p < 0.05) and the volume difference compared between patients and volunteers. Results: the volume of the compromised trigeminal nerve in patients with trigeminal neuralgia was lower than on the contralateral healthy side, with the difference between healthy and compromised side statistically significant (p < 0.05). In all other patients and in all volunteers, no significant difference was found between the volume of the healthy and compromised nerve. The volume difference between the healthy and compromised side in patients with trigeminal neuralgia was significantly higher (p < 0.05) than in all other patients and volunteers. Conclusion: atrophy of the trigeminal nerve caused by a nerve-vessel conflict can be detected by MRI. Only patients with trigeminal neuralgia show this unilateral atrophy. Therefore, it is possible to demonstrate the result of the nerve-vessel conflict and to determine the consequences of such a conflict. (orig.) [German] Ziel: Die Studie wurde mit der Frage durchgefuehrt, ob die bei Patienten mit Trigeminusneuralgie durch einen Gefaess-Nerven-Konflikt bedingte Atrophie des Nervs magnetresonanztomographisch darstellbar ist. Methodik: 39 Patienten (Trigeminusneuralgie, Trigeminusneuropathie, atypischer Gesichtsschmerz) und 25 Probanden wurden prospektiv magnetresonanztomographisch untersucht. In koronaren T1- und T2-Gradientenechosequenzen wurde der zisternale Abschnitt des N. trigeminus mittels

Prospektive Entwicklung des postoperativen Sprachverstehens nach Tympanoplastik bei chronischer Otitis media

OpenAIRE

Knof, B; Plotz, K; Krack, A; Stumper, J; Schönfeld, R

2013-01-01

Einleitung: Tympanoplastiken I/III bei chron. Otitis media COM (mesotympanalis CMOM und epitympanalis CEOM). In der Literatur werden erfolgreiche operative Behandlungen mit Verringerung der Schallleitungskomponente (air-bone gap) belegt (Gierke et al. 2011). Aus Sicht des Patienten steht die Verbesserung des Hörvermögens und des Sprachverstehens im Alltag im Vordergrund. Das Ziel war die Untersuchung der Entwicklung des Hörvermögens in Ruhe sowie im Störgeräusch.Methoden: An den Hör- und Sp...

CONTROLE GERENCIAL: UMA ANÁLISE NAS EMPRESAS CONTÁBEIS DA CIDADE DE CAICÓ/RN.

Directory of Open Access Journals (Sweden)

Hugo Azevedo Rangel de Morais

2016-07-01

Full Text Available O controle gerencial de uma empresa é necessário para um eficiente desenvolvimento interno. Com as mudanças constantes das legislações e a evolução da tecnologia de informação nas empresas contábeis, é essencial o controle gerencial eficiente, através dele será possível identificar como está a vida da empresa no seu dia a dia. Neste trabalho é mostrada a importância do controle gerencial para as empresas contábeis, situada na cidade de Caicó/RN, demonstrando a sua importância para auxiliar nas tomadas de decisões. O presente estudo tem como objetivo geral de analisar se nas empresas contábeis da cidade de Caicó existe um controle gerencial que os auxiliem nas tomadas de decisões, verificando se existem a prestação de serviço de contabilidade gerencial e analisando a importância do controle gerencial para os empresários. A contextualização do tema trata-se de pesquisas bibliográficas. A metodologia desenvolvida na pesquisa é classificada como descritiva, do ponto de vista de sua natureza é uma pesquisa aplicada, tendo uma abordagem qualitativa por ter caráter exploratório, já no que se refere aos procedimentos técnicos trata-se de um levantamento. Observou que os empresários tem conhecimento em relação à importância do controle gerencial, a maioria coloca em pratica obtendo uma boa classificação dos controles com confiabilidade para auxiliar nas tomadas de decisões, foi detectado que a maioria das empresas faz um planejamento dos objetivos a serem controlados.

Role of radiotherapy in age-related macular degeneration. A prospective study; Photonentherapie der subfovealen choroidalen Neovaskularisation bei altersabhaengiger Makuladegeneration. Ergebnisse einer prospektiven Studie an 40 Patienten

Energy Technology Data Exchange (ETDEWEB)

Prettenhofer, U.; Mayer, R.; Oechs, A.; Pakisch, B.; Stranzl, H.; Willfurth, P.; Hackl, A. [Univ. Graz (Austria). Abt. fuer Strahlentherapie; Haas, A. [Univ. Graz (Austria). Universitaets-Augenklinik

1998-12-01

Aim: To determine the effect of external beam radiotherapy on subfoveal choroidal neovascularization in age-related macular degeneration. Patients and methods: Between September 1995 and July 1996, 40 patients (9 males and 31 females; mean age 74 years, range 61 to 83 years) were included in a prospective study. Eight patients had classic, well defined neovascularisations, 32 patients had occult lesions. Complete ophthalmic investigations included visual acuity contrast sensitivity as well as fluorescein and indocyanine green angiographic examinations prior to treatment and 1, 3, 6, and 12 months after radiotherapy. External beam radiotherapy (8-MV photons) was delivered with a total dose of 14.4 Gy in 8 fractions of 1.8 Gy per day. The field size averaged 5.5x4.5 cm. Results: No treatment related morbidity during or after treatment was obtained. After 6 months follow-up the visual acuity was improved in 2 (5%) patients and maintained at pretreatment level in 17 (42%) patients. However, 12 months post treatment a stable situation was found in 6 (15%) patients and a decrease in visual acuity in 34 (85%) patients. The central visual fields deteriorated significantly from 16.5 decibel (dB) to 12.4 dB. The enlargement of exsudats and neovascular membranes increased 5- to 7-fold. At 12 months after treatment, 3 (7.5%) patients stated that they had improved vision subjectively, 12 (30%) patients had no change and 25 (62.5%) patients suffered from subjective decrease in visual acuity. Conclusions: Using a total dose of 14.4 Gy/1.8 Gy no difference concerning visual acuity and exsudative changes in comparison to the natural history on age-related macular degeneration was obtained after 12 months. However, the results of multicenter studies are to be awaited. (orig.) [Deutsch] Ziel: Ueberpruefung der Effektivitaet der Strahlentherapie als Therapieansatz in der Behandlung subfovealer choroidaler Neovaskularisation bei altersabhaengiger Makuladegeneration. Patienten und

Radiotherapy for treatment of bursitis. Indication, technique, own results, literature survey; Strahlentherapie bei der Periarthropathia humeroscapularis (PHS). Indikation, Technik, eigene Ergebnisse, Literaturuebersicht

Energy Technology Data Exchange (ETDEWEB)

Heyd, R. [Staedtische Kliniken Offenbach am Main (Germany). Strahlenklinik]|[Frankfurt Univ. (Germany). Klinik fuer Strahlentherapie und Onkologie; Schopohl, B.; Boettcher, H.D. [Frankfurt Univ. (Germany). Klinik fuer Strahlentherapie und Onkologie

1998-12-31

Our own experience covers 41 primarily chronic cases. The patients have been irradiated with a telecobalt device with isocentric opposing fields, receiving 4x1.0 Gy within two weeks; 15 patients (36.6%) received a second radiation treatment (8 Gy), and one patient (2.4%) a third (12 Gy). After a follow-up period of 44 months on the average, the results were: Complete remittence of pain in 44%, abatement of pain in 44%, and no effect in 12%. Improvement of shoulder joint motility was achieved in 78%. The rate of recidivation was as low as 3%. A statistical evaluation of data acquired revealed that the prognosis is worst in case of a long period of pain preceding commencement of radiotherapy, combined with intensive prior therapy. (orig./CB) [Deutsch] In einer eigenen Untersuchung wurden 41 ueberwiegend chronische Faelle mit 4x1,0 Gy in 2 Wochen an einem Telekobaltgeraet mit isozentrischen Gegenfeldern behandelt, 15 (36,6%) erhielten eine 2. Bestrahlungsserie (8 Gy), ein Fall (2,4%) eine Dritte (12 Gy). Nach einem Nachbeobachtungszeitraum von median 44 Monaten fand sich bei 44% eine komplette Schmerzremission, bei 44% eine Linderung und 12% waren ohne einen Einfluss der Behandlung. Eine Verbesserung der Motilitaet des Schultergelenkes wurde bei 78% erreicht. Die Rezidivrate lag bei nur 3%. Nach statistischer Bearbeitung der Daten erwies sich die Kombination einer langen Beschwerdedauer vor Einleitung der Radiotherapie und intensiver Vortherapie als prognostisch unguenstiger (p=0,02). (orig.)

Technical and marketing aspects of power use in industry and trade; Technik- und Marketingaspekte bei der industriellen und gewerblichen Stromanwendung

Energy Technology Data Exchange (ETDEWEB)

Mann, E.W.; Duenkelberg, R.

1997-02-01

Using electric power permits energetic optimization of production processes in industry and trade. Because of the trend towards qualitatively high-grade products, the energy form electric power plays a key role. Increased power demand on the part of industrial customers coincides with increased competition in the energy supply sector at the national and international levels. Within short, therefore, these industrial customers may prompt a change in preferences at the supplier side. Utilities will adopt suitable marketing concepts in order to gain profile with their customers as service providers. Operating close to customers will essentially influence customer satisfaction and, thereby, customer loyalty. (orig./RHM) [Deutsch] Durch die Stromanwendung koennen Produktionsprozesse in Industrie und Gewerbe energetisch optimiert werden. Bei dem Trend zu qualitativ hochwertigen Produkten nimmt die Energieform Strom eine Schluesselstellung ein. Die erhoehte Stromnachfrage der Industriekunden trifft auf zunehmenden Wettbewerb bei der Energieversorgung auf nationaler und internationaler Ebene, wodurch in Kuerze Industriekunden andere Praeferenzen bei den Energielieferanten setzen koennen. Durch geeignete Marketingkonzepte werden sich die Energieversorgungsunternehmen (EVU) als Energiedienstleister ihrer Kunden profilieren. Die Naehe zum Kunden wird wesentlich die Kundenzufriedenheit und damit letztlich auch die Kundenloyalitaet beeinflussen. (orig./RHM)

Beckenbodenbeschwerden bei Fahrradfahrerinnen und mögliche Therapieansätze

Directory of Open Access Journals (Sweden)

Lyatoshinsky P

2016-01-01

Full Text Available Einleitung und Hypothese: Fahrradfahren ist nicht nur ein immer beliebter werdender Freizeitsport, sondern auch ein immer intensiver genutztes Fortbewegungsmittel. Somit ist es mittlerweile von großer Bedeutung, herauszufinden, welchen negativen Einfluss das Fahrradfahren auf den menschlichen Körper hat. Dieser Review fasst die aktuelle Evidenz zur Epidemiologie, Therapie und Prävention der Genital- und Beckenbodenbeschwerden bei weiblichen Fahrradfahrerinnen zusammen.brMethoden: Zwei Metadatenbanken, OvidSP und Deutsches Institut für Medizinische Dokumentation und Information (DIMDI, wurden auf Studien durchsucht, die über Genital- und Beckenbodenbeschwerden bei weiblichen Fahrradfahrerinnen berichteten und mögliche Therapie- oder Prophylaxeansätze untersuchten. Für die Literaturrecherche wurden folgende Schlagwörter verwendet: „female“, „bicycling“, „pelvic floor“, „lower urinary tract symptoms“ und „vulvar diseases“.brErgebnis: Die Suche ergab 1219 Artikel. Nach Entfernen der Duplikate aus dem Ergebnispool wurden 763 Publikationen nach relevanten Titeln untersucht. Letztendlich konnten 12 Fachartikel für unser Review herangezogen werden. 10 Studien waren Beobachtungsstudien und 2 experimentell. Symptome, die hierbei mit Fahrradfahren assoziiert wurden, waren: Schmerz und Neuropathien in der Beckenbodenregion sowie urologische Dysfunktionen und Hautverletzungen. Breitere und konventionelle Sättel führten zu einer geringeren Symptomatik als Sättel mit einer Lochung sowie schmälere Sportsättel.brZusammenfassung: Die Qualität der gegenwärtigen Studien war im Allgemeinen niedrig. Dennoch gibt es Evidenz dafür, dass Radfahrerinnen unter sehr ähnlichen Symptomen leiden wie Radfahrer: von kleineren Hautläsionen bis hin zu neurologischen Beschwerden.

Valuasi Harga Wajar Saham Sektor Perbankan Yang Go Public Di BEI

OpenAIRE

Khairi, Sherly Emita

2011-01-01

Investment on stock needs analyisis about valuation of stocks to calculate the intrinsic value of each stocks based on the its fundamental data. The aim of this research is to calculate the intrinsic stock prices of the two company which included in financial sectors and to see whether the stocks of the companies is in the undervalued or overvalued conditions. This research takes samples of financial sectors which are got IPO in BEI from 2005 to 2010. As the samples, it is chosen two banks...

Effects of traction on the blood circulation of femoral head: DSA study on a canine model

International Nuclear Information System (INIS)

Yang Xiujun; Xiao Jian; Ren Qile; Fu Shiping; Li Wei; Xiao Xiangsheng

2010-01-01

Objective: To study the influence of traction on the blood circulation of femur head and its evaluation by DSA. Methods: Using micro-catheter, transfemoral selective femoral circumflex arteriography in 22 healthy dogs was performed in unilateral hip before (Group A, n=22) and immediately (Group B, n=22), 30 (Group D, n=22), 60 (Group E, n=20), 90 (Group F, n=10), 120 (Group G, n= 10) minutes during 2 kg skin hip traction, and immediately after traction removal (Group H, I, J, L and O) , and 30 minutes after traction removal with 60, 90 and 120 minutes continuous traction (Group K, M and P) , and 60 minutes after traction removal with 90 and 120 minutes continuous traction (Group N and Q). DSA was also performed immediately during 4 kg weight traction before continuous traction in 12 hips (Group C). Blood circulation of the femoral head was evaluated mainly by observing its perfusion and time of circulation. Femur head perfusion was assessed as good scoring 3, poor scoring 2 and extremely poor scoring 1. Femur head circulation time was assessed as normal scoring 3, prolonged scoring 2 and remarkably prolonged scoring 1. Analysis of variance was employed for analysis of the angiographic findings between different groups. Results: Good femoral head perfusion in Group A to Q was 22, 0, 0, 0, 0, 0, 0, 22, 22, 1, 18, 0, 0, 8, 0, 0 and 1 hips respectively, poor one was 0, 22, 8, 22, 15, 4, 1, 0, 0, 15, 2, 4, 6, 2, 1, 3 and 8 hips, respectively, extremely poor one was 0, 0, 4, 0, 5, 6, 9, 0, 0, 4, 0, 6, 4, 0, 9, 7 and 1 hips, respectively; and normal femoral head blood circulation time was 22, 0, 0, 0, 0, 0, 0, 22, 22, 1, 18, 0, 0, 8, 0, 0 and 1 hips, respectively, prolonged one was 0, 22, 9, 22, 15, 4, 2, 0, 0, 15, 2, 5, 7, 2, 2, 4 and 8 hips, respectively, remarkably prolonged one was 0, 0, 3, 0, 5, 6, 8, 0, 0, 4, 0, 5, 3, 0, 8, 6 and 1 hips, respectively. F value of femoral head perfusion among group A and B,group B and C, group B, D, E, F and G, Group H, I, J, L and O

USER'S GUIDE TO THE PERSONAL COMPUTER VERSION OF THE BIOGENIC EMISSIONS INVENTORY SYSTEM (PC-BEIS2)

Science.gov (United States)

The document is a user's guide for an updated Personal Computer version of the Biogenic Emissions Inventory System (PC-BEIS2), allowing users to estimate hourly emissions of biogenic volatile organic compounds (BVOCs) and soil nitrogen oxide emissions for any county in the contig...

Betriebseigenschaften der CEDARs für Likelihood-Teilchenidentifikation bei COMPASS

CERN Document Server

Gensler, Armin

Die CEDAR Detektoren bei COMPASS können genutzt werden um Teilchen zu identifizieren. In dieser Arbeit wird eine Unregelmäßigkeit untersucht, die in den Daten der Photomultiplier der CEDARs auftritt. Insbesondere wird ermittelt, welche Daten davon betroffen sind und wie diese identifiziert und herausgefiltert werden können. Dabei zeigt sich, dass etwa 10% aller Events betroffen sind. Anschließend werden die Auswirkungen auf das in [4] beschriebene Likelihod-Identifikationsverfahren für Pionen und Kaonen analysiert, wobei sich heraus stellt, dass sich die Effizienz der Verfahrens dadurch deutlich verbessern lässt.

Prognose und Verlauf der Posttraumatischen Belastungsstörung bei Soldaten der Bundeswehr. Längsschnittstudie zur Neuvalidierung des Kölner Risikoindex-Bundeswehr (KRI-Bw)

OpenAIRE

Dunker, Sibylle

2009-01-01

In einer Längsschnittuntersuchung werden Ausmaß und Verlauf der Posttraumatischen Belastungsstörung (PTBS) bei deutschen Soldaten nach einem Auslandseinsatz erfasst. Die Stichprobe besteht aus 650 Afghanistan-Rückkehrern, die 2-4 Monate und 6 Monate nach dem Auslandseinsatz befragt wurden. Die PTBS-Prävalenz beträgt 6 Monate nach der Rückkehr für die Gesamtstichprobe 1.9-7.5%, für traumatisierte Soldaten 3.7-12.1%. Die intraindividuelle Auswertung zeigt heterogene Symptomverläufe bei traumati...

Evaluation of angiographic delayed vasospasm due to ruptured aneurysm in comparison with cerebral circulation time measured by IA-DSA

Energy Technology Data Exchange (ETDEWEB)

Okada, Yoshikazu; Shima, Takeshi; Nishida, Masahiro; Yamane, Kanji; Okita, Shinji; Hatayama, Takashi; Yoshida, Akira; Naoe, Yasutaka; Shiga, Naoko (Chugoku Rosai Hospital, Hiroshima (Japan))

1994-05-01

Delayed vasospasm due to ruptured aneurysm has been basically evaluated by angiographic changes in contrast to clinical features such as delayed ischemic neurological deficits (DIND). However, the discrepancies between angiographic and clinical findings have been pointed out. In this study, angiographic changes and cerebral circulation time in ruptured aneurysms were simultaneously investigated with IA-DSA. Thirty-two patients, who had ruptured aneurysms at the anterior circle of Willis and neck clippings at the acute stage, were investigated. Carotid angiogram was performed with IA-DSA on the 7-13th day after the attack. Angiographic changes were evaluated by Fischer's classification and circulation time was calculated in the following way. A time-density curve was obtained at the two ROI's: the C3-C4 portion and the rolandic vein. Circulation time was defined by the difference between the time showing peak optical density at the carotid and the venous portion. The control value of this circulation time obtained from 20 cases with non-rupture aneurysm and epilepsy was 3.4 sec (53 year old) on the average. X-ray CT scan examination was performed at the same time and clinical features were observed every day. Angiographically, 3 cases were free from vasospasm, 18 cases were found to present slight to moderate vasospasm, and 11 cases showed severe vasospasm. Circulation time in patients with no spasm was 3.6 seconds, in patients with slight to moderate vasospasm it was 4.3 seconds and in patients with severe vasospasm it was 6.8 seconds. Ten patients showing cerebral infarction on CT scans demonstrated significantly long circulation time, 7.0 seconds on the average. And all patients having severe vasospasm with circulation time more than 6 seconds presented DIND such as hemiparesis. (author).

MRI for therapy planning in patients with atrial septum defects; MRT zur Therapieplanung bei Patienten mit Vorhofseptumdefekt

Energy Technology Data Exchange (ETDEWEB)

Huber, A.; Rummeny, E. [Klinikum rechts der Isar, Technische Universitaet Muenchen, Institut fuer Radiologie, Muenchen (Germany); Prompona, M.; Reiser, M.; Theisen, D. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany); Kozlik-Feldmann, R. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Klinik und Poliklinik fuer Kinderkardiologie, Muenchen (Germany); Muehling, O. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Medizinische Klinik I, Muenchen (Germany)

2011-01-15

The aim of this study was to determine the value of a combined magnetic resonance imaging (MRI) protocol including steady-state free precession (SSFP) imaging, phase-contrast measurements and contrast-enhanced MR angiography (CE-MRA) for presurgical or preinterventional diagnostic imaging in patients with suspected atrial septum defects. Out of 65 MRI studies of patients with suspected atrial septum defects, 56 patients were included in the study. The atrial septum defects were identified on cine images. Velocity encoded flow measurements were used to determine shunt volumes, which were compared with invasive oxymetry in 24 patients. Contrast-enhanced MRI was used to assess the thoracic vessels in order to detect vascular anomalies. The findings were compared with the intraoperative results. A total of 24 patients with high shunt volumes were treated either surgically (16 patients) or interventionally (8 patients) and 32 patients with low shunt volumes did not require surgical or interventional treatment. The vascular anomaly, which in all cases was anomalous pulmonary venous return, was confirmed by the intraoperative findings. The type and location of atrial septal defects which required treatment, were confirmed intraoperatively or during the intervention. The results of shunt quantification by MRI showed a good correlation with the results of invasive oximetry (r=0.91, p <0.0001). A combined MRI protocol including cine SSFP images, velocity-encoded flow measurements and CE-MRA is an accurate method for preoperative and preinterventional evaluation of atrial septum defects. (orig.) [German] Ziel war es, die Wertigkeit eines kombinierten MRT-Protokolls aus Funktionsuntersuchung, Flussmessung und MR-Angiographie zur praeoperativen oder -interventionellen Abklaerung bei Patienten mit Vorhofseptumdefekt zu evaluieren. Ingesamt wurden 56 Patienten mit Vorhofseptumdefekt aus einem Kollektiv von 65 Patienten mit Verdacht auf Vorhofseptumdefekt, die im MRT untersucht

Magnetic resonance spectroscopy for inflammatory brain diseases; Magnetresonanzspektroskopie bei entzuendlichen Hirnerkrankungen

Energy Technology Data Exchange (ETDEWEB)

Papanagiotou, P.; Grunwald, I.Q.; Hartmann, K.M.; Politi, M.; Roth, C.; Reith, W. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar (Germany); Farmakis, G. [Universitaetsklinikum des Saarlandes, Klinik fuer Nuklearmedizin, Homburg/Saar (Germany)

2008-06-15

Magnetic resonance spectroscopy (MRS) is a non-invasive method for investigation of cerebral metabolite concentrations in various pathologic conditions. The clinical use of MRS for intracranial disorders is well established. In this review the characteristic MRS findings for the most important inflammatory brain diseases will be discussed. (orig.) [German] Die Magnetresonanzspektroskopie (MRS) ist eine nichtinvasive Methode, die die Messung der Konzentration zerebraler Metaboliten erlaubt. Die Verwendung der MRS bei verschiedenen intrakraniellen Erkrankungen ist gut etabliert. In diesem Review werden die MRS-Charakteristiken der wichtigsten entzuendlichen Hirnerkrankungen diskutiert. (orig.)

Global Ionospheric Modelling using Multi-GNSS: BeiDou, Galileo, GLONASS and GPS.

Science.gov (United States)

Ren, Xiaodong; Zhang, Xiaohong; Xie, Weiliang; Zhang, Keke; Yuan, Yongqiang; Li, Xingxing

2016-09-15

The emergence of China's Beidou, Europe's Galileo and Russia's GLONASS satellites has multiplied the number of ionospheric piercing points (IPP) offered by GPS alone. This provides great opportunities for deriving precise global ionospheric maps (GIMs) with high resolution to improve positioning accuracy and ionospheric monitoring capabilities. In this paper, the GIM is developed based on multi-GNSS (GPS, GLONASS, BeiDou and Galileo) observations in the current multi-constellation condition. The performance and contribution of multi-GNSS for ionospheric modelling are carefully analysed and evaluated. Multi-GNSS observations of over 300 stations from the Multi-GNSS Experiment (MGEX) and International GNSS Service (IGS) networks for two months are processed. The results show that the multi-GNSS GIM products are better than those of GIM products based on GPS-only. Differential code biases (DCB) are by-products of the multi-GNSS ionosphere modelling, the corresponding standard deviations (STDs) are 0.06 ns, 0.10 ns, 0.18 ns and 0.15 ns for GPS, GLONASS, BeiDou and Galileo, respectively in satellite, and the STDs for the receiver are approximately 0.2~0.4 ns. The single-frequency precise point positioning (SF-PPP) results indicate that the ionospheric modelling accuracy of the proposed method based on multi-GNSS observations is better than that of the current dual-system GIM in specific areas.

Aspects of radiation protection during chest X-radiography; Strahlenhygienische Aspekte bei der Roentgenuntersuchung des Thorax

Energy Technology Data Exchange (ETDEWEB)

Seidenbusch, M.C.; Schneider, K. [Dr. von Haunersches Kinderspital, Klinikum der Universitaet Muenchen, Institut fuer Klinische Radiologie - Kinderradiologie, Muenchen (Germany)

2015-07-15

Radiation safety in conventional X-ray diagnostics is based on the concepts of justification, optimization of an X-ray examination and limitation of the radiation exposure achieved during the examination. Optimization of an X-ray examination has to be considered as a multimodal process in which all technical components of the X-ray equipment have to be adapted to each other and also have to be adapted to the anthropometric characteristics of patients and the clinical indications. In this article the technical components of a conventional pediatric chest X-radiograph are presented, and recommendations for optimizing chest X-rays in children are provided. The following measures are of prime importance: correct x-ray beam limitation, using the posteroanterior projection when possible and not using anti-scatter grids in children under approximately 8 years old. In pediatric radiology chest x-rays that are taken not at the peak of inspiration can also be of some diagnostic significance. Optimization of an X-ray examination inevitably results in the limitation of radiation exposure. (orig.) [German] Die Strahlenhygiene in der konventionellen radiologischen Diagnostik basiert auf der Trias Rechtfertigung, Optimierung bzw. Limitierung der Roentgenuntersuchung bzw. Strahlenexposition. Die Optimierung einer Roentgenuntersuchung ist als multimodaler Prozess aufzufassen, in welchem saemtliche technische Komponenten der Roentgeneinrichtung sowohl miteinander als auch mit den anthropometrischen Eigenschaften des Patienten und der klinischen Fragestellung abzustimmen sind. Im vorliegenden Beitrag werden die technischen Komponenten bei der konventionellen Roentgenuntersuchung des paediatrischen Thorax in ihrer Beziehung zueinander dargestellt und Empfehlungen fuer eine Optimierung der konventionellen Thoraxaufnahme bei Kindern ausgesprochen. Die wichtigsten Massnahmen bestehen in einer korrekten Einblendung, in der Anfertigung der Aufnahmen im posteroanterioren Strahlengang und im

Hints on cost- and energy saving during lime-sand brick production; Hinweise zur Kosten- und Energieeinsparung bei der Kalksandstein-Produktion

Energy Technology Data Exchange (ETDEWEB)

Eden, W.

2001-05-01

The publication contains hints for reduction of energy consumption and cost in lime-sand brick production. The information was compiled by Bundesverband Kalksandsteinindustrie e.V. and was derived from technical discussions of the master seminars on production technology of the years 1995 - 2000, consultations form member organizations, or from other sources. [German] Diese Arbeit ist eine Zusammenstellung von Hinweisen zur Reduzierung des Energieverbrauchs und der Kostensenkung bei der KS-Produktion und soll eine Hilfestellung bei entsprechenden Rationalisierungsmassnahmen in den Mitgliedsunternehmen sein. Die hier aufgefuehrten Hinweise und Anregungen entstammen den Fachdiskussionen der Meisterseminare zur Produktionstechnik aus den Jahren 1995 bis 2000, Beratungsgespraechen fuer Mitgliedsunternehmen oder wurden dem Bundesverband Kalksandsteinindustrie eV freundlicherweise fuer die Gemeinschaftsarbeit zur Verfuegung gestellt. (orig.)

Modeling and Assessment of Precise Time Transfer by Using BeiDou Navigation Satellite System Triple-Frequency Signals

Science.gov (United States)

Zhang, Pengfei; Zhang, Rui; Liu, Jinhai; Lu, Xiaochun

2018-01-01

This study proposes two models for precise time transfer using the BeiDou Navigation Satellite System triple-frequency signals: ionosphere-free (IF) combined precise point positioning (PPP) model with two dual-frequency combinations (IF-PPP1) and ionosphere-free combined PPP model with a single triple-frequency combination (IF-PPP2). A dataset with a short baseline (with a common external time frequency) and a long baseline are used for performance assessments. The results show that IF-PPP1 and IF-PPP2 models can both be used for precise time transfer using BeiDou Navigation Satellite System (BDS) triple-frequency signals, and the accuracy and stability of time transfer is the same in both cases, except for a constant system bias caused by the hardware delay of different frequencies, which can be removed by the parameter estimation and prediction with long time datasets or by a priori calibration. PMID:29596330

Pathophysiologie des Kollagenstoffwechsels bei Patienten mit Induratio penis plastica (IPP

Directory of Open Access Journals (Sweden)

Lahme S

2000-01-01

Full Text Available Die Pathogenese der IPP ist bis heute nicht geklärt. Histopathologische Untersuchungen zeigen, daß der Kollagenstoffwechsel eine Rolle spielt. Dies veranlaßte uns zur genauen Analyse der Kollagenstoffwechselparameter bei IPP. Bei 11 Patienten mit IPP und 11 Kontrollpersonen wurden Kollagenstoffwechselparameter (Prokollagen III [PIIIP], PMN-Elastase [PMN-E], Fibronektin [FN], Fibronektinrezeptor [FN-R] und alpha1-Proteinase-Inhibitor [alpha1-PI] im cavernösen und peripheren Blut bestimmt. PMN-E, PIIIP, FN und FN-R waren in den beiden Untersuchungsgruppen nicht unterschiedlich. Die peripher venösen unterschieden sich nicht von den cavernösen Blutproben. Sowohl im peripher venös (158,55 mg/dl als auch im cavernös entnommenen Blut (168,29 mg/dl war die Konzentration des a1-PI signifikant niedriger als in der Kontrollgruppe (214,82 mg/dl. An einem zweiten Kollektiv von 23 Patienten wurden Analysen des Phänotyps für alpha1-PI im Hinblick auf das Vorliegen von genetisch determinierten Mangelallelen vorgenommen. Hier zeigte sich kein signifikanter Unterschied zu einem Kontrollkollektiv von 19 gesunden Probanden. Die alpha1-PI Erniedrigung der IPP-Patienten ist signifikant und liegt unterhalb des Normalwertbereichs für die gesunde Population. Ein Mangel an alpha1-PI kann zur Aktivitätserhöhung der Proteasen und zum Umbau des Kollagengewebes führen. Möglicherweise kommt es zusammen mit einem lokal wirksamen Einflußfaktor schließlich zur dystrophen Kalzifikation. Die humangenetischen Untersuchungen sprechen nicht für eine genetische Determinierung des alpha1-PI-Mangels, sondern legen eine erworbene hepatische Störung nahe.

Combined PET/MRI in cerebral and paediatric diagnostics; Kombinierte PET/MRT-Diagnostik bei zerebralen und paediatrischen Fragestellungen

Energy Technology Data Exchange (ETDEWEB)

Pfluger, T.; Vollmar, C.; Porn, U.; Schmid, R.; Dresel, S.; Leinsinger, G.; Schmid, I.; Winkler, P.; Fischer, S.; Hahn, K. [Klinik und Poliklinik fuer Nuklearmedizin, Ludwig-Maximilians-Univ. Muenchen (Germany)

2002-07-01

The aim of this overview is presentation of MRI and PET as synergistic modalities for combined analysis of morphology and function. For operative planning in epilepsy surgery, definition of the epileptogenic focus based on functional PET diagnostics and morphological MRI is decisive. For staging and follow-up examinations in oncology, MRI should be complemented by PET for the assessment of tumor vitality. In paediatric oncology patients we could demonstrate a therapy relevant increase of sensitivity/specificity with combined PET/MRI in contrast to single modalities. In the brain, full spectrum of digital image registration and three-dimensional reconstruction should be used. In extracranial cases, image fusion is disturbing due to a partial loss of image information of single modalities by the fusion process. (orig.) [German] Ziel dieser Uebersicht ist die Darstellung der MRT und PET als synergistische Verfahren zur Analyse von Morphologie und Funktion. Zur Resektionsplanung im Rahmen der Epilepsiechirurgie ist die Definition des Epilepsiefokus anhand der funktionellen PET-Diagnostik und die exakte Kenntnis der zerebralen Morphologie aus der MRT ganz entscheidend. Im Rahmen des onkologischen Stagings und bei Verlaufskontrollen ist wegen der geringeren Spezifitaet der MRT die additive PET zur Beurteilung der Tumorvitalitaet erforderlich. Anhand eines paediatrisch-onkologischen Patientengutes konnten wir zeigen, dass mit der kombinierten PET/MRT-Diagnostik eine therapierelevante Steigerung der Sensitivitaet/Spezifitaet gegenueber den Einzeluntersuchungen moeglich ist. Bei zerebralen Fragestellungen sollte das gesamte Spektrum der digitalen Bildfusion mit direkter Ueberlagerung mehrerer Modalitaeten und anschliessender dreidimensionaler Rekonstruktion ausgeschoepft werden. Bei extrakraniellen Fragestellungen ist die direkte Bildueberlagerung eher hinderlich, da die Bildinformation der Einzelmodalitaeten durch die Fusion teilweise verloren geht. (orig.)

Gibt es geschlechtsspezifische Unterschiede im Training bei älteren Personen?

Directory of Open Access Journals (Sweden)

Vonbank K

2010-01-01

Full Text Available Die Lebenserwartung hat sich im vergangenen Jahrhundert in etwa verdoppelt. Zu den Faktoren, die die Lebenserwartung beeinflussen, zählen neben den sozialen Umweltfaktoren und der genetischen Veranlagung auch die Bewegung und Ernährung. Die mittlere Lebenserwartung der Frauen ist um durchschnittlich 4,2 Jahre länger als die der Männer. Training kann bis ins hohe Alter durchgeführt werden und führt neben einer Verbesserung der Lebenserwartung und der -qualität auch zu einer signifikanten Abnahme der Sturzhäufigkeit bei älteren Personen. In diesem Artikel sollen geschlechtsspezifische Unterschiede bezogen auf die Leistungsfähigkeit und das Training angesprochen werden.

Europe CERN recherche - Pret de 300 millions d'euros de la BEI pour l'accelerateur de particules

CERN Multimedia

2002-01-01

"La Banque europeenne d'investissement (BEI) va preter 300 millions d'euros pour financer la phase finale de la construction du grand accelerateur de particules LHC (Large Hadron Collider) du CERN, a indique jeudi l'organisation europeenne pour la recherche nucleaire" (1/2 page).

Clean Slate Environmental Remediation DSA for 10 CFR 830 Compliance

International Nuclear Information System (INIS)

James L. Traynor, Stephen L. Nicolosi, Michael L. Space, Louis F. Restrepo

2006-01-01

Clean Slate Sites II and III are scheduled for environmental remediation (ER) to remove elevated levels of radionuclides in soil. These sites are contaminated with legacy remains of non-nuclear yield nuclear weapons experiments at the Nevada Test Site, that involved high explosive, fissile, and related materials. The sites may also hold unexploded ordnance (UXO) from military training activities in the area over the intervening years. Regulation 10 CFR 830 (Ref. 1) identifies DOE-STD-1120-98 (Ref. 2) and 29 CFR 1910.120 (Ref. 3) as the safe harbor methodologies for performing these remediation operations. Of these methodologies, DOE-STD-1120-98 has been superseded by DOE-STD-1120-2005 (Ref. 4). The project adopted DOE-STD-1120-2005, which includes an approach for ER projects, in combination with 29 CFR 1910.120, as the basis documents for preparing the documented safety analysis (DSA). To securely implement the safe harbor methodologies, we applied DOE-STD-1027-92 (Ref. 5) and DOE-STD-3009-94 (Ref. 6), as needed, to develop a robust hazard classification and hazards analysis that addresses non-standard hazards such as radionuclides and UXO. The hazard analyses provided the basis for identifying Technical Safety Requirements (TSR) level controls. The DOE-STD-1186-2004 (Ref. 7) methodology showed that some controls warranted elevation to Specific Administrative Control (SAC) status. In addition to the Evaluation Guideline (EG) of DOE-STD-3009-94, we also applied the DOE G 420.1 (Ref. 8) annual, radiological dose, siting criterion to define a controlled area around the operation to protect the maximally exposed offsite individual (MOI)

Cryotherapy in rheumatic disorders; Kryotherapie bei rheumatischen Erkrankungen

Energy Technology Data Exchange (ETDEWEB)

Soerensen, H. [Rheumaklinik Immanuel-Krankenhaus, Berlin (Germany). Innere Rheumatologische Abt.

1994-12-31

When applied locally, cold therapy (cryotherapy) has the effect of inhibiting inflammation, occluding blood vessels, and stopping bleeding. Active rheumatic inflammation, activated arthrosis, and swelling after injury can be alleviated by local cold application, while heat application would worsen the situation. In whole-body cryotherapy the whole patient, wearing only a bathing suit, is exposed to a temperature of -100 C. The present paper descrcribes the cold room of the Immanuel Hospital in Berlin-Wannsee. (BWI) [Deutsch] Kaeltetherapie (Kryotherapie) wirkt lokal angewendet entzuendungshemmend, blutgefaessabdichtend und blutstillend. Eine aktive rheumatische Entzuendung, aktivierte Arthrose und Schwellungsreaktionen bei Verletzungen werden durch lokale Kaelteanwendungen gedaempft, wogegen Waerme den akuten Zustand verschlimmern wuerde. In der Ganzkoerperkaeltetherapie wird der ganze Mensch in Badebekleidung einer realen Temperatur von -100 C ausgesetzt. Der vorliegende Beitrag beschreibt die Kaeltekammer des Immanuel Krankenhauses in Berlin Wannsee. (BWI)

Measures to enhance rational energy use in electric drives. Final report; Massnahmen zur Foerderung der rationellen Energienutzung bei elektrischen Antrieben. Endbericht

Energy Technology Data Exchange (ETDEWEB)

Reichert, J.; Schleich, J.; Herzer, G.; Toensing, E. [Fraunhofer-Institut fuer Systemtechnik und Innovationsforschung (ISI), Karlsruhe (Germany); Rath, U.; Hellmann, R. [Ingenieurbuero fuer Energieberatung, Haustechnik und Oekologische Konzepte GbR (eboek), Tuebingen (Germany)

1999-05-01

Electric drives account for nearly 60 % of the total power consumption in Germany (70 % in the industrial sector and about 44 % in the small consumer sector). There is a high potential for savings (Landwehr et al. 1996, ISR et al. 1996, Nadel et al. 1992) but it is little used so far. The study attempts to identify and systematize the limits set by the market to the application of energy conservation measures in electric motors. This is followed by an outline of strategies to overcome these obstacles. Experience from other countries are integrated where efforts were made to put the potential savings into practice. [German] Der Kraftstrombedarf fuer elektrische Antriebe betraegt in Deutschland knapp 60% des gesamten Stromeinsatzes (ca. 70% des Industriestrombedarfs und ca. 44% des Strombedarfs im Sektor Kleinverbrauch). Trotz dieser hohen Anteile ist bisher bei keinem der Marktteilnehmer (Motoren- und Anlagenhersteller, Haendler und Endanwender) grosses Interesse an Stromsparmassnahmen im Bereich Elektromotoren zu erkennen. Zudem zeigen erste grobe Schaetzungen (Landwehr et al. 1996, ISR et al. 1996, Nadel et al. 1992), dass im Bereich Elektromotoren erhebliche wirtschaftliche Einsparpotentiale bestehen. Durch eine Erhoehung des Wirkungsgrades allein lassen sich ca. 3% einsparen. Groessere Potentiale koennen durch Drehzahlregelung - ca. 10% - und vor allem bei Optimierung des gesamten Systems (Stromuebertragung - Motor - Regelung - Kraftuebertragung - Arbeitsmaschine) - ueber 20% - erschlossen werden. Ziel dieser Studie ist es, zunaechst die Marktbeschraenkungen bei der Umsetzung von Massnahmen zur rationellen Energienutzung bei Elektromotoren zu identifizieren und zu systematisieren. Im Anschluss daran werden moegliche Strategien zur Ueberwindung dieser Marktbeschraenkungen aufgezeigt, systematisiert und analysiert. In diesem Zusammenhang werden auch Erfahrungen aus anderen Laendern, in denen von politischer und wirtschaftlicher Seite zum Teil betraechtliche

Hochaufgelöste Magnetresonanz-Bildgebung der Mäuseaorta zur Bestimmung der Dynamik funktioneller Parameter durch Laufrad-Training bei ApoE-Knock-Out-Mäusen

OpenAIRE

Offenberger, Wolfgang

2009-01-01

Einführung: Atherosklerose ist eine führende Ursache von Morbidität und Mortalität weltweit. Die ApoE-Knock-Out-Maus (ApoE-/-) ist das wichtigste Tiermodell für das Studium der Atherosklerose und von Interventionen auf diese Erkrankung. Mittels hochaufgelöster Magnet-Resonanz-Bildgebung ist es möglich, eine nicht-invasive in-vivo Gefäß-Charakterisierung bei Mäusen durchzuführen. In dieser Arbeit wurden die Auswirkungen von Sport auf die Gefäßfunktion der Aorta ascendens und abdominalis bei Ap...

Analysis of fallopian tube recanalization in 37 cases with Foley catheter infusion under pressure through DSA

International Nuclear Information System (INIS)

Huang Qiuli; Song Kankan; Wu Anle; Shu Jing

2000-01-01

Objective: To investigate the safe, effective, simple and direct method in the re-canalization of fallopian tubal obstruction. Methods: Fallopian tubal obstructive infertility in 37 cases were re-canalized with Foley catheter under pressure infusion through DSA, including primary infertility in 17 cases and secondary infertility in 20 cases. The average infertility term was 4 years. Results: In the 37 cases, 18 cases were treated once, twice in 16 cases, and thrice in 3 cases. The oviduct recanalization rate was 95% (35/37) with one failure and another unsatisfactory. After several times of recanalization in 19 cases, the pelvic cavity adhesion were reduced in 15 cases (79%), no change in 3 cases (16%), and aggravated in one case (5%). Conclusions: This method is simple, cheap, safety, effective and low in X-ray exposure. The authors insist on the pelvic cavity adhesion is still the chief cause of infertility after recanalization and still need other kind of treatment

Die Symmelie (Sirenomelie) bei Mensch und Tier : ein komplexes Fehlbildungs-Syndrom ; dargestellt an vier neuen Fällen unter Berücksichtigung der gesamten bisher bekannten Literatur

OpenAIRE

Plendl, Philipp Johannes

2002-01-01

Der Begriff Symmelie (Sirenomelie, Sympodie oder Meerjungfrauensyndrom) steht für eine Fehlbildung im Bereich des Beckens und der unteren Extremitäten, welche ganz oder teilweise miteinander verschmelzen. Diese seltene Missbildung tritt bei 1 von 100.000 Geburten in Erscheinung und sie ist in den meisten Fällen nicht mit dem Leben vereinbar. Das Synonym »Sirenomelie« findet seinen Ursprung bei den wohl bekannten Sirenen der griechischen Mythology. In dieser Arbeit werden vier bisher unver...

A FORMAÇÃO COMPORTAMENTAL DE AUDITORES CONTÁBEIS INDEPENDENTES: UM ESTUDO MULTICASO

Directory of Open Access Journals (Sweden)

Luiz Alberton

2002-11-01

Full Text Available RESUMO
O presente artigo tem como objetivo apresentar uma proposta de um modelo de formação comportamental para auditores contábeis independentes. Deste modo, inicialmente, discorre-se sobre os aspectos que devem ser considerados pelo profissional responsável pela gestão das pessoas nas organizações que prestam serviços de auditoria contábil independente, e do perfil destas pessoas requerido pelas empresas. Em seguida são identificadas as teorias que tratam da gestão de pessoas nas organizações, especificamente nos processos de recrutamento e seleção, capacitação e avaliação de desempenho. As empresas buscam profissionais com talentos e, principalmente, que saibam manter o equilíbrio entre a razão e a emoção no ambiente de trabalho. Na literatura que versa sobre a profissão do auditor contábil, é dada muita ênfase aos aspectos técnicos, tratando superficialmente ou renegando os aspectos comportamentais considerados importantes ao desempenho destes profissionais. Para confirmar essas afirmações e dar suporte ao delineamento do modelo, é realizada uma pesquisa de campo com os responsáveis pela gestão de pessoas em quatro empresas internacionais de auditoria contábil independente, que fazem parte das big five, e em uma empresa nacional. Assim, para o delineamento do modelo de formação, a ênfase desta pesquisa recai sobre os aspectos de liderança, comunicação, motivação, negociação, coaching, mentoring, administração de conflitos, trabalho em equipe, técnica de entrevista, análise transacional e de programação neurolingüística, que podem ser utilizados para o desenvolvimento de auditores contábeis independentes, de forma que possam melhorar suas condições de competitividade e empregabilidade. Portanto, são incorporados esses conceitos como ponto de partida para o delineamento de um modelo de formação comportamental

Revisiting the Continuing Bonds Theory: The Cultural Uniqueness of the Bei Dao Phenomenon in Taiwanese Widows/Widowers.

Science.gov (United States)

Lee, Wan-Lin; Hou, Yi-Chen; Lin, Yaw-Sheng

2017-10-01

In the present study, we used the phenomenological approach to rediscover the ontological meaning of relationships with the deceased in Taiwanese widows/widowers. We first revised the original Western definitions of grief, bereavement, and mourning to fit Taiwanese culture. We used the word bei dao to indicate the mixed nature of grief and mourning in the Taiwanese bereavement process. Then we reanalyzed data from a previous study, which was conducted in 2006. In the previous qualitative research, each subject was interviewed 3 to 4 times in the mourning state over an 18-month interval that began at the point of the spouse's death. Results showed that two main themes emerged in the present analysis: (a) a blurred boundary of life and death and (b) a transformation of ethical bonds. The present study reveals the culturally unique aspects of the Taiwanese bei dao process. Limitations of the present study and future directions are discussed and reflected.

Modeling and Assessment of Precise Time Transfer by Using BeiDou Navigation Satellite System Triple-Frequency Signals

Directory of Open Access Journals (Sweden)

Rui Tu

2018-03-01

Full Text Available This study proposes two models for precise time transfer using the BeiDou Navigation Satellite System triple-frequency signals: ionosphere-free (IF combined precise point positioning (PPP model with two dual-frequency combinations (IF-PPP1 and ionosphere-free combined PPP model with a single triple-frequency combination (IF-PPP2. A dataset with a short baseline (with a common external time frequency and a long baseline are used for performance assessments. The results show that IF-PPP1 and IF-PPP2 models can both be used for precise time transfer using BeiDou Navigation Satellite System (BDS triple-frequency signals, and the accuracy and stability of time transfer is the same in both cases, except for a constant system bias caused by the hardware delay of different frequencies, which can be removed by the parameter estimation and prediction with long time datasets or by a priori calibration.

Planungsunterstützung für Pankreasoperationen bei Hyperinsulinismus von Kindern

Science.gov (United States)

Dornheim, J.; Preim, B.; Preim, U.; Mohnike, K.; Blankenstein, O.; Füchtner, F.; Mohnike, W.; Empting, S.; Mohnike, K.

Auf Basis von sechs PET/CT-Datensätzen des Pankreas wird eine Computerunterstützung für die Teilresektion der Bauchspeicheldr üse (Pankreas) bei fokalem Hyperinsulinismus von Kindern entwickelt. Ziel ist es, die Lokalisation des krankhaften Fokus im Pankreasgewebe präoperativ dreidimensional zu visualisieren, um so die Sicherheit des Eingriffs zu erhöhen. Die relevanten anatomischen Strukturen werden im CT segmentiert und anschließend dreidimensional visualisiert. Der im PET erkennbare Fokus wird in diese anatomische 3D-Visualisierung eingeblendet. Es zeigt sich eine klare Erkennbarkeit des Fokus in allen sechs Fällen.

Molekulargenetische Studie zur Verbreitung und Interaktion von PCV-2 bei Haus- und Wildschweinen

OpenAIRE

Bronnert, Bastian Balthasar Marcel

2014-01-01

Im Rahmen der vorliegenden Arbeit wurden Wild- und Hausschweingewebeproben aus den Jahren 2005 bis 2008 mittels nested PCR auf das Vorkommen von PCV-2 untersucht und die positiv getesteten Proben mittels Realtime PCR quantifiziert. Zusätzlich wurden die Proben im Institut für Pathologie der Justus-Liebig-Universität histologisch und immunhistologisch untersucht (Dissertation Hohloch). Ziel war es das Vorkommen von PCV-2 und die Häufigkeit von PCV-2 assoziierter Erkankungen bei Haus- und Wilds...

Retrospektive Studie zur Ermittlung der Effizienz sprechunterstützender Operationen bei velopharyngealer Insuffizienz

OpenAIRE

Wellmann, S.S. (Sandra)

2013-01-01

In der vorliegenden Studie wurde retrospektiv an einem Patientenkollektiv die Effizienz der vier sprechunterstützenden Operationen Velopharyngoplastik mit kaudal gestieltem Lappen (VPP kaudal), Push back - Verfahren, VPP kaudal und Push - back kombiniert und die Levatorplastik anhand der Hypernasalitaät prä - und postoperativ untersucht. Die durch die Logopäden ermittelten Erfolgsquoten lagen für VPP kaudal, VPP kaudal mit Push back, Push back und Levatorplastik bei 89%, 88%, 43% und 75% (p>...

Magnetic resonance maging of epidural and subdural spinal hematomas; Magnetresonanztomographie bei epiduralen und subduralen spinalen Haematomen

Energy Technology Data Exchange (ETDEWEB)

Felber, S. [Universitaetskliniken Innsbruck (Austria). Klinik fuer Neurologie]|[Universitaetskliniken Innsbruck (Austria). Inst. fuer Magnetresonanz]|[Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie; Langmaier, J. [Universitaetskliniken Innsbruck (Austria). Klinik fuer Neurochirurgie; Judmaier, W. [Universitaetskliniken Innsbruck (Austria). Inst. fuer Magnetresonanz]|[Universitaetskliniken Innsbruck (Austria). Klinik fuer Radiologie; Dessl, A. [Universitaetskliniken Innsbruck (Austria). Klinik fuer Radiologie; Ortler, M. [Universitaetskliniken Innsbruck (Austria). Klinik fuer Neurochirurgie; Birbamer, G. [Universitaetskliniken Innsbruck (Austria). Klinik fuer Neurologie]|[Universitaetskliniken Innsbruck (Austria). Inst. fuer Magnetresonanz; Piepgras, U. [Universitaetskliniken des Saarlandes, Homburg/Saar (Germany). Inst. fuer Neuroradiologie

1994-11-01

wurde. Wir berichten ueber 9 Patienten, die primaer magnetresonanztomographisch diagnostiziert wurden. Bei allen Patienten wurden T1, Spindichte und T2-gewichtete Bilder erzeugt. Zusaetzlich wurden T2*-gewichtete Gradientenechosequenzen angewendet. Die Magnetresonanztomographien wurden mit dem intraoperativen Situs korreliert. Computertomographische Befunde waren bei 4 und myelographische Befunde waren bei 2 Patienten vorhanden. Die Haematome komprimierten in 2 Faellen das Zervikalmark, bei 6 Patienten das Thorakalmark und bei 2 Patienten Konus und Cauda. Die Magnetresonanztomographie ergab 6 epidurale und 3 subdurale Haematome, operativ handelte es sich um 5 epidural und 4 subdurale Blutungen. In einem Fall konnte die Kernspintomographie nicht zwischen epi- und subduraler Lokalisation unterscheiden. Perakute Haematome (<24 h) waren isointens auf T1-gewichteten Bildern und hatten gemischte Signalintensitaet auf T2- und T*-gewichteten Bildern (n=3). Akute Blutungen (24 h bis 3 Tage) waren ebenfalls isointens auf T1 aber hypointens auf T- und T2*-gewichteten Bildern (n=4). Erst nach 7 Tagen fand sich die methaemoglobintypische Hyperintensitaet auf T1- und T2-gewichteten Bildern (n=2). Diese Ergebnisse unterstreichen, dass die Magnetresonanztomographie perakute und akute spinale Blutungen adaequat diagnostizieren kann. Die exakte Beurteilung der kraniokaudalen Ausdehnung verbessert die Operationsplanung. (orig.)

BNP ist ANP, Endothelin und Noradrenalin als Prognoseindikator bei chronisch herzinsuffizienten Patienten überlegen

OpenAIRE

Zugck C; Gerhards A; Haass M; Katz N; Kell R; Krüger C; Schellberg D

2001-01-01

Zu den etablierten Prognoseindikatoren bei Patienten mit chronischer Herzinsuffizienz zählen der Herz-Thorax-Quotient in der Röntgen-Thoraxaufnahme (HTQ), die linksventrikuläre Ejektionsfraktion (LVEF) und die maximale Sauerstoffaufnahme unter Belastung (VO2max). Darüber hinaus wird zahlreichen neurohumoralen Parametern eine prognostische Wertigkeit zugeschrieben. An 166 Patienten mit chronischer Herzinsuffizienz (Alter 54 ± 9 Jahre; 70 % dilatative Kardiomyopathie; 30 % KHK; LVEF 21 ± 9 %) ...

Hollywood Megaplex cinema building at Pasching near Linz, Austria; Hollywood Megaplex. Grosskino in Pasching bei Linz

Energy Technology Data Exchange (ETDEWEB)

Anon.

1996-08-01

The contribution describes the projecting and construction of a large cinema building at Pasching near Linz. It goes into detail about heating systems, air conditioning systems, and energy conservation measures. (HW) [Deutsch] Es wird berichtet ueber die Planung und die Ausfuehrung der Baumassnahmen Grosskino in Pasching bei Linz. Im Einzelnen: Heizungssysteme; Klimaanlage; Energiesparmassnahmen. (HW)

Late results after intertrochanteric varus angulation in aseptic femoral head necrosis in adults. Spaetergebnisse nach intertrochanterer Varisierungsosteotomie bei der aseptischen Hueftkopfnekrose Erwachsener

Energy Technology Data Exchange (ETDEWEB)

Schneider, E.; Ahrendt, J.; Niethard, F.U.; Blaesius, K. (Heidelberg Univ. (Germany, F.R.). Orthopaedische Klinik und Poliklinik)

1989-04-01

25 patients suffering from femoral head necrosis in 30 hip joints were radiologically studied for an average of 11.6 years following intertrochanteric varus angulation osteotomy. Preoperatively only stages 2 and 3 according to Meyers were seen. The follow-up results could be distributed into 4 groups. At best the osteonecrosis was reconstructed within 6 to 9 years while the trabeculae started to become rearranged within 2 to 4 years. At worst, rapid destruction in absence of bony reaction was observed. The ability of the bone outside the osteonecrosis to react to changed circumstances following angulation osteotomy correlates with long-term results. This may indicate a general osteopathy even outside the necrotic area. (orig.).

Scintigraphic examinations after stent implantation in central airways; Szintigraphische Untersuchungen bei Stents in den zentralen Atemwegen

Energy Technology Data Exchange (ETDEWEB)

Richter, W.S.; Kettner, B.I.; Munz, D.L. [Klinik und Poliklinik fuer Nuklearmedizin, Universitaetsklinikum Charite, Medizinische Fakulteat der Humboldt-Univ. zu Berlin (Germany)

1998-03-01

Endotracheal and endobronchial stent implantation has been developed as an effective treatment of benign and malignant airway stenosis and of tracheo- or bronchoesophageal fistulas. The selection of the stent type depends on the kind and site of disease. Chest X-ray and bronchoscopy are the procedures of choice for monitoring of stent position, structure, and function. However, with scintigraphic methods the effects of stent implantation on pulmonary ventilation and perfusion can be assessed non-invasively. The validation of the effect of a stent implantation on mucociliary and tussive clearance remains to be elucidated. (orig.) [Deutsch] Die endotracheale und -bronchiale Stentimplantation wurde in den letzten Jahren als effektive Massnahme bei benignen und malignen Stenosen der Atemwege, drohendem Atemwegsverschluss und bei tracheo- bzw. bronchooesophagealen Fisteln eingefuehrt. Der gewaehlte Stenttyp richtet sich nach dem Implantationsort und den krankheitsbedingten Veraenderungen. Zum Monitoring von Lage, Struktur und Funktion eines Stents dienen Thoraxroentgenaufnahmen und die Bronchoskopie. Nuklearmedizinische Verfahren koennen nicht-invasiv den Effekt der Stenteinlage auf Lungenventilation und -perfusion belegen. Die Validierung des Effekts einer Stentimplantation auf die mukoziliaere und tussive Clearance steht noch aus. (orig.)

Aspekte der Osteoporosetherapie und Frakturprävention bei geriatrischen Patienten

Directory of Open Access Journals (Sweden)

Gosch M

2010-01-01

Full Text Available Aktuell beträgt der Anteil der Personen 65 Jahre in Österreich 17 %. Nach Schätzungen der WHO wird sich dieser Anteil bis 2025 verdoppeln. Parallel mit der demographischen Veränderung steigt auch die Inzidenz der Oberschenkelhalsfraktur von zurzeit 16.000/Jahr auf 25.000 im Jahr 2050. Mit einer jährlichen Inzidenz von 19,7/100.000 Einwohner weist Österreich innerhalb der EU eine der höchsten Zahlen auf. Die hüftnahen Frakturen sowie die Wirbelkörperfrakturen treten überwiegend als Folge einer bestehenden Osteoporose auf. Die Qualität der Osteoporosebehandlung stellt die Grundvoraussetzung für einen erfolgreichen präventiven Behandlungsansatz dar. Eine ausreichende Kalzium- und Vitamin-D-Zufuhr hat gerade im höheren Alter große Bedeutung, insbesondere auch im Hinblick auf die Sturzprävention. Für einzelne Bisphosphonate, Teriparatid und Strontiumranelat konnte eine signifikante Reduktion des Frakturrisikos bei geriatrischen Patienten nachgewiesen werden. Aus aktuellen Studien wissen wir, dass wir bei Patienten mit einem hohen Risiko eine „number needed to treat“ (NNT von 1:15 erreichen können. Trotz zahlreicher therapeutischer Möglichkeiten steigt die Inzidenz weiter an. Aus verschiedenen internationalen Studien sind uns mögliche Ursachen für diese Entwicklung bekannt. Neben der ungenügenden Compliance der Patienten ist auch die fehlende Awareness der Ärzte problematisch. Eine weitere Herausforderung in der Behandlung der Osteoporose und deren Folgen stellt beim älteren Patienten das Sturzrisiko dar. Screeninguntersuchungen werden in vielen Leitlinien empfohlen, sind im klinischen Alltag jedoch eher die Ausnahme. Wissenschaftliche Daten für geriatrische Patienten bestätigen die Wirksamkeit einer Therapie auch in dieser Altersgruppe. Bedauerlicherweise fließen die vorliegenden Erkenntnisse kaum in die klinische Praxis ein.

Molecular imaging in neurological diseases; Molekulare Bildgebung bei neurologischen Erkrankungen

Energy Technology Data Exchange (ETDEWEB)

Reimold, M.; Fougere, C. la [Universitaetsklinikum Tuebingen, Abteilung Nuklearmedizin und Klinische Molekulare Bildgebung, Department Radiologie, Tuebingen (Germany)

2016-07-15

In neurodegeneration and in neuro-oncology, the standard imaging procedure, magnetic resonance imaging (MRI), shows limited sensitivity and specificity. Molecular imaging with specific positron-emission tomography (PET) and single-photon emission computed tomography (SPECT) tracers allows various molecular targets and metabolic processes to be assessed and is thus a valuable adjunct to MRI. Two important examples are referred to here: amino acid transport for neuro-oncological issues, and the recently approved PET tracers for detecting amyloid depositions during the preclinical stage of Alzheimer's disease. This review discusses the clinical relevance and indications for the following nuclear medicine imaging procedures: amyloid PET, {sup 18}F-fluorodeoxyglucose (FDG)-PET, and dopamine transporter (DaT)-SPECT for the diagnosis of dementia and the differential diagnosis of Parkinson's disease, in addition to amino acid PET for the diagnosis of brain tumors and somatostatin receptor imaging in meningioma. (orig.) [German] Die Magnetresonanztomographie (MRT) weist als Standardverfahren bei neurodegenerativen und neuroonkologischen Fragestellungen eine eingeschraenkte Sensitivitaet und Spezifitaet auf. Die nuklearmedizinische molekulare Bildgebung mit spezifischen Positronenemissionstomographie(PET)- und single-photon-emission-computed-tomography(SPECT)-Tracern ermoeglicht die Darstellung verschiedener molekularer Targets bzw. Stoffwechselprozesse und stellt damit eine wichtige Ergaenzung zur MRT dar. Hier sei exemplarisch auf die Darstellung des Aminosaeuretransports im Rahmen neuroonkologischer Fragestellungen verwiesen, sowie auf die bereits im praeklinischen Stadium der Alzheimer-Demenz nachweisbaren Amyloidablagerungen mit hierfuer seit Kurzem zugelassenen PET-Tracern. Dieser Uebersichtsbeitrag bespricht die klinische Bedeutung bzw. die Indikationen der folgenden nuklearmedizinischen Untersuchungsverfahren: der Amyloid-PET, der {sup 18}F

Mineralogical investigations of the role of the clay fraction in geothermal energy use; Mineralogische Untersuchungen zur Rolle der Tonfraktion bei der Gewinnung geothermischer Energie

Energy Technology Data Exchange (ETDEWEB)

Althaus, E; Frosch, G [Karlsruhe Univ. (T.H.) (Germany). Mineralogisches Inst.

1997-12-01

Authigenic clay minerals strongly influence the quality of geothermal reservoir systems. Their precipitation may drastically change the properties of reservoir sandstones. They interact more strongly with non-equilibrium fluids than most other mineral phases. The most abundant clay minerals in geothermal wells of Northeastern Germany are kaolinite, illite and mixed-layer minerals. Experiments are being carried out to study the dissolution rates of these minerals in NaCl brines at different pH-values. (orig.) [Deutsch] Im Rahmen des BMBF-Projektes `Evaluierung geowissenschaftlicher und wirtschaftlicher Bedingungen fuer die Nutzung hydrogeothermaler Ressourcen` werden am Mineralogischen Institut der Universitaet Karlsruhe (T.H.) Experimente zur Stabilitaet von Tonmineralen in geothermischen Systemen durchgefuehrt. Die Untersuchungen beziehen sich auf Gesteine und Solen, wie sie durch die nordostdeutschen Geothermiebohrungen Neustadt-Glewe, Rheinsberg und Neubrandenburg aufgeschlossen sind. Die Untersuchten Gesteinsproben enstammen der oberen Trias und dem Jura. Die vergleichbaren stratigraphischen Einheiten sind in den Bohrungen in unterschiedlicher Teufe und Maechtigkeit anzutreffen: So finden sich die Contorta-Schichten (Raetkeuper) bei Neustadt-Glewe in ca. 2200 m, bei Rheinsberg in ca. 1680 m und bei Neubrandenburg in ca. 1250 m Tiefe. (orig.)

Anzeichen einer linearen dosis-effekt beziehung bei sehr kleinen bestrahlungsdosen

CERN Document Server

Diehl, I.

1980-01-01

Zur Aufstellung einer Strahlungsdosis - Effekt - Kurve bei kleinen Dosen wurde der Mikrokerntest verwendet, da er relativ einfach und gleich- zeitig sehr empfindlich ist. Die Bohne Vicia Faba (Fillbasket) wurde mit 60Co Gammastrahlen und mit hochenergetischen Neutronen bestrahlt. Die Neutronen wurden von 600 MeV Protonen, die auf ein Be—Target auftrafen produziert und unter einem Winkel von 0 Grad extrahiert. Informationen fiber Dosimetrie und Eigenschaften der verwandeten Strahlung wurder bereits an anderer Stelle beschriebenl) des gleichen auch Einzelheiten fiber die Aufzucht der BORE Vicia Fabaz). Nach der Bestrahlung wurden jeweils 5 Bohnen zu bestimmten Zeitpunkten fixiert und danach die Prfiparate herge— stellt. Pro Préparat wurden 1000 Zellen ausgewertet.

Radiotherapy for solitary plasmacytoma and multiple myeloma; Strahlentherapie bei solitaerem Plasmozytom und multiplem Myelom

Energy Technology Data Exchange (ETDEWEB)

Schmaus, M.C. [Universitaetsklinikum Heidelberg, Klinik fuer Radioonkologie und Strahlentherapie, Heidelberg (Germany); Neuhof, D. [MVZ Strahlentherapie und Nuklearmedizin Weinheim, Weinheim (Germany)

2014-06-15

Solitary plasmacytoma and multiple myeloma require a differentiated radiotherapy. The irradiation for plasmacytoma with an adequate total dose (medullary 40-50 Gy or extramedullary 50-60 Gy) leads to a high degree of local control with a low rate of side effects. In cases of multiple myeloma radiotherapy will achieve effective palliation, both in terms of recalcification as well as reduction of neurological symptoms and analgesia. In terms of analgesia the rule is the higher the single dose fraction the faster the reduction of pain. As part of a conditioning treatment prior to stem cell transplantation radiotherapy contributes to the establishment of a graft versus myeloma effect (GVM). (orig.) [German] Das solitaere Plasmozytom und das multiple Myelom fordern eine differenzierte Strahlenbehandlung. Bei Plasmozytomen fuehrt eine Bestrahlung mit ausreichender Gesamtdosis (medullaer 40-50 Gy oder extramedullaer 50-60 Gy) zu einer hohen Lokalkontrolle mit einer geringen Rate an Nebenwirkungen. Beim multiplen Myelom kann die Strahlentherapie eine effektive Palliation sowohl hinsichtlich Rekalzifikation als auch Reduktion neurologischer Symptomatik und Analgesie erzielen. Hinsichtlich der Analgesie gilt: Je hoeher die Einzeldosis, desto schneller der Wirkeintritt. Im Rahmen einer Konditionierungstherapie vor Stammzelltransplantation traegt die Strahlentherapie zur Etablierung eines Graft-versus-Myelom-Effekts (GvM) bei. (orig.)

Comparison of Ultra-Rapid Orbit Prediction Strategies for GPS, GLONASS, Galileo and BeiDou.

Science.gov (United States)

Geng, Tao; Zhang, Peng; Wang, Wei; Xie, Xin

2018-02-06

Currently, ultra-rapid orbits play an important role in the high-speed development of global navigation satellite system (GNSS) real-time applications. This contribution focuses on the impact of the fitting arc length of observed orbits and solar radiation pressure (SRP) on the orbit prediction performance for GPS, GLONASS, Galileo and BeiDou. One full year's precise ephemerides during 2015 were used as fitted observed orbits and then as references to be compared with predicted orbits, together with known earth rotation parameters. The full nine-parameter Empirical Center for Orbit Determination in Europe (CODE) Orbit Model (ECOM) and its reduced version were chosen in our study. The arc lengths of observed fitted orbits that showed the smallest weighted root mean squares (WRMSs) and medians of the orbit differences after a Helmert transformation fell between 40 and 45 h for GPS and GLONASS and between 42 and 48 h for Galileo, while the WRMS values and medians become flat after a 42 h arc length for BeiDou. The stability of the Helmert transformation and SRP parameters also confirmed the similar optimal arc lengths. The range around 42-45 h is suggested to be the optimal arc length interval of the fitted observed orbits for the multi-GNSS joint solution of ultra-rapid orbits.

Just in Time DSA the Hanford Nuclear Safety Basis Strategy

Energy Technology Data Exchange (ETDEWEB)

JACKSON, M.W.

2002-06-01

The U.S. Department of Energy, Richland Operations Office (RL) is responsible for 30 hazard category 2 and 3 nuclear facilities that are operated by its prime contractors, Fluor Hanford, Incorporated (FHI), Bechtel Hanford, Incorporated (BHI) and Pacific Northwest National Laboratory (PNNL). The publication of Title 10, Code of Federal Regulations, Part 830, Subpart B, Safely Basis Requirements (the Rule) in January 2001 requires that the Documented Safety Analyses (DSA) for these facilities be reviewed against the requirements of the Rule. Those DSAs that do not meet the requirements must either be upgraded to satisfy the Rule, or an exemption must be obtained. RL and its prime contractors have developed a Nuclear Safety Strategy that provides a comprehensive approach for supporting RL's efforts to meet its long-term objectives for hazard category 2 and 3 facilities while also meeting the requirements of the Rule. This approach will result in a reduction of the total number of safety basis documents that must be developed and maintained to support the remaining mission and closure of the Hanford Site and ensure that the documentation that must be developed will support: Compliance with the Rule; A ''Just-In-Time'' approach to development of Rule-compliant safety bases supported by temporary exemptions; and Consolidation of safety basis documents that support multiple facilities with a common mission (e.g. decontamination, decommissioning and demolition [DD&D], waste management, surveillance and maintenance). This strategy provides a clear path to transition the safety bases for the various Hanford facilities from support of operation and stabilization missions through DD&D to accelerate closure. This ''Just-In-Time'' Strategy can also be tailored for other DOE Sites, creating the potential for large cost savings and schedule reductions throughout the DOE complex.

Just in Time DSA the Hanford Nuclear Safety Basis Strategy

International Nuclear Information System (INIS)

JACKSON, M.W.

2002-01-01

The U.S. Department of Energy, Richland Operations Office (RL) is responsible for 30 hazard category 2 and 3 nuclear facilities that are operated by its prime contractors, Fluor Hanford, Incorporated (FHI), Bechtel Hanford, Incorporated (BHI) and Pacific Northwest National Laboratory (PNNL). The publication of Title 10, Code of Federal Regulations, Part 830, Subpart B, Safely Basis Requirements (the Rule) in January 2001 requires that the Documented Safety Analyses (DSA) for these facilities be reviewed against the requirements of the Rule. Those DSAs that do not meet the requirements must either be upgraded to satisfy the Rule, or an exemption must be obtained. RL and its prime contractors have developed a Nuclear Safety Strategy that provides a comprehensive approach for supporting RL's efforts to meet its long-term objectives for hazard category 2 and 3 facilities while also meeting the requirements of the Rule. This approach will result in a reduction of the total number of safety basis documents that must be developed and maintained to support the remaining mission and closure of the Hanford Site and ensure that the documentation that must be developed will support: Compliance with the Rule; A ''Just-In-Time'' approach to development of Rule-compliant safety bases supported by temporary exemptions; and Consolidation of safety basis documents that support multiple facilities with a common mission (e.g. decontamination, decommissioning and demolition [DD and D], waste management, surveillance and maintenance). This strategy provides a clear path to transition the safety bases for the various Hanford facilities from support of operation and stabilization missions through DD and D to accelerate closure. This ''Just-In-Time'' Strategy can also be tailored for other DOE Sites, creating the potential for large cost savings and schedule reductions throughout the DOE complex

Use of MRI in interventions in head and neck surgery; Die Nutzung der Magnetresonanztomographie bei Interventionen auf dem Gebiet der HNO-Heilkunde

Energy Technology Data Exchange (ETDEWEB)

Schulz, T.; Schneider, J.P.; Schmidt, F.; Kahn, T. [Leipzig Univ. (Germany). Klinik und Poliklinik fuer Diagnostische Radiologie; Bootz, F.; Weber, A. [Leipzig Univ. (Germany). Klinik und Poliklinik fuer HNO-Heilkunde; Weidenbach, H. [Leipzig Univ. (Germany). Inst. fuer Pathologie; Heinke, W. [Leipzig Univ. (Germany). Klinik fuer Anaesthesie und Intensivmedizin; Koehler-Brock, A. [Leipzig Univ. (Germany). Klinik und Poliklinik fuer Strahlentherapie und Radioonkologie

2001-05-01

Presentation of new concepts and applications of MR-guided head and neck surgery are presented. Examples of diagnostic and therapeutic procedures such as evaluation of transseptal tumor biopsies, placement of afterloading catheters for brachytherapy, and microscopic surgery of paranasal sinuses in the open MRI are discussed. Material and Methods: 24 MRI-guided ENT-procedures (14 transsphenoidal biopsies, one transnasal biopsy, 6 placements of brachytherapy catheters, and 3 operations of the paranasal sinuses) were performed in an open 0.5 T MR system. Results: localisation and/or extension of all lesions as well as the placement of biopsy needles or catheters were determined with great precision during the interventions. Conclusions: surgical risk and postoperative morbidity are significantly reduced in MR-guided surgery of the petroclival region and the region of head and neck compared to other, conventional methods. Thus, interventional MRI-guidance optimizes minimal invasive surgery and catheter placement in difficult anatomical regions like the petroclival region. (orig.) [German] Vorstellung neuer Konzepte und Anwendungen der interventionellen MRT in der HNO-Heilkunde und Erlaeuterung am Beispiel diagnostischer und therapeutischer Interventionen. Evaluierung transseptaler Tumorbiopsien der petroclivalen Region, der Platzierung von Afterloadingsonden zur Brachytherapie und der Durchfuehrbarkeit mikroskopgestuetzter Nasennebenhoehlenoperationen. Material und Methoden: bei 24 Patienten wurden MR-gestuetzte Prozeduren im offenen MRT Signa SP/i durchgefuehrt (14 transsphenoidale Biopsien, eine transnasale Biopsie, 6 Afterloadingkatheter-Platzierungen und 3 Nasennebenhoehlenoperationen). Ergebnisse: bei allen Operationen war die Lokalisation des zu bioptierenden Tumors bzw. des Ausma paragraph es der Polyposis und seiner Umgebung moeglich. Sowohl die Biopsien als auch die Sondenplatzierungen und die Nasennebenhoehlenoperationen waren mit gro paragraph er Praezision

PENGARUH GOOD CORPORATE GOVERNANCE DAN LEVERAGE TERHADAP KINERJA KEUANGAN (STUDI PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI TAHUN 2011-2012

Directory of Open Access Journals (Sweden)

Wuryaningsih Dwi Lestari

2016-08-01

Full Text Available Penelitian ini bertujuan untuk menganalisis pengaruh good corporategovernance terdiri dari kepemilikan institusional, proporsi dewan komisaris independen, komite audit dan leverage terhadapkinerja keuangan pada perusahaan manufaktur yang terdaftar di BEI tahun 2011-2012.Sampel penelitian ini adalah 134 perusahaan manufaktur yang terdaftar di BEI tahun 2011-2012. Data laporan keuangan diperoleh dari annual report masing-masing perusahaan yang didapat dari situs resmi Bursa Efek Indonesia (www.idx.co.id dan Indonesian Capital Market Directory (ICMD. Metode pengambilan sampel yang digunakan adalah purposive sampling.Sedangkan Metode analisis yang digunakan adalah metode analisis regresi linear berganda. Hasil pengujian hipotesis menunjukkan bahwa kepemilikan institusional berpengaruh terhadap kinerja keuangan. Proporsi dewan komisaris independen dan komite audit tidak berpengaruh terhadap kinerja keuangan. Serta leverage berpengaruh terhadap kinerja keuangan

Imaging of nasopharyngeal diseases; Bildgebung bei Erkrankungen des Nasopharynx

Energy Technology Data Exchange (ETDEWEB)

Koesling, S.; Hofmockel, T. [Martin-Luther-Universitaet Halle-Wittenberg, Klinik und Poliklinik fuer Diagnostische Radiologie, Halle (Germany); Knipping, S. [Martin-Luther-Universitaet Halle-Wittenberg, Klinik und Poliklinik fuer Hals-, Nasen-, Ohrenheilkunde, Kopf- und Halschirurgie, Halle (Germany)

2009-01-15

This article gives an overview about the main nasopharyngeal pathologies and incidental findings, which a radiologist could be confronted with in daily practice. These include nasopharyngeal cysts, lymphoid hyperplasia, juvenile angiofibroma, carcinomas and non-Hodgkin lymphoma. Typical radiological findings, possibilities for making a specific diagnosis, differential diagnosis and description of the spread of a neoplasm are the central points. Investigation techniques and clinical signs are briefly summarized. (orig.) [German] Dieser Beitrag gibt einen Ueberblick ueber nasopharyngeale Erkrankungen und Zufallsbefunde, mit denen der Radiologe haeufig und weniger haeufig konfrontiert werden kann. Dazu zaehlen zystische Raumforderungen, die hyperplastische Rachenmandel, das juvenile Nasenrachenfibrom, Nasopharynxkarzinom und Non-Hodgkin-Lymphom. Im Vordergrund stehen dabei das radiologische Erscheinungsbild, Moeglichkeiten einer artdiagnostischen Zuordnung, differenzialdiagnostische Aspekte und bei Neoplasien Aussagen zur Ausbreitungsdiagnostik. Untersuchungstechnische und klinische Aspekte sowie die Diagnosesicherung werden kurz erwaehnt. (orig.)

Multimodal imaging in the elastase-induced aneurysm model in rabbits: a comparative study using serial DSA, MRA and CTA

International Nuclear Information System (INIS)

Doerfler, A.; Becker, W.; Wanke, I.; Goericke, S.; Oezkan, N.; Forsting, M.

2004-01-01

Background and Purpose: The elastase-induced aneurysm model in rabbits has proved to be suitable for testing new endovascular occlusion devices. The purpose of this study was to evaluate different imaging modalities for the depiction of anatomy and size of elastase-induced aneurysms and for serial follow-up imaging. Materials and Methods: Elastase-induced aneurysms were created in eight Chinchilla bastard rabbits by endoluminal incubation of porcine elastase. Serial imaging was performed using intravenous DSA (IVDSA), contrast-enhanced MRA (CEMRA), and time-of-flight MRA (TOF) 14 days, 4 weeks and 3 months after aneurysm creation. Intraarterial DSA (IADSA) and CT angiography (CTA) were performed after 3 months. Aneurysm size and geometry (height H, width W, neck width N) were compared. Results: On IVDSA after two weeks mean aneurysm height was 6.2 mm (range 2.8-11.0 mm), mean aneurysm neck width was 2.7 mm (range 2.0-4.2 mm) and mean aneurysm neck width was 2.7 mm (range 2.0-4.2 mm). We did not observed any statistically significant change in aneurysm dimensions during follow-up at 4 weeks (CEMRA: H: 5.4, W: 2.4, N: 2.4; TOF: H: 5.7, W: 2.4, N: 2.7) and 3 months (CEMRA: H: 5.8, W: 2.6, N: 2.6; TOF: H: 6.9, W: 2.8, N: 3.0). Aneurysm dimensions could be best seen on IADSA (H: 6.2, W: 3.0, N: 2.7) with good correlation to CTA (r=0.94; H: 6.1, W: 2.8, N: 2.6), CE-MRA (r=0.92), and TOF (r=0.97). TOF was superior to CEMRA in delineating the aneurysm wall. Conclusions: Serial imaging using MRA, CTA or intravenous and intraarterial angiography is feasible in the elastase-induced aneurysm model. Contrast-enhanced MRA, TOF-MRA and CTA showed good correlation to IADSA and are all suitable for non-invasive pretherapeutic measurement of aneurysm size. (orig.) [de

Digitised and intervention radiology in cardiovascular disorders. Digitale und interventionelle Radiologie bei Herz- und Gefaesskrankheiten

Energy Technology Data Exchange (ETDEWEB)

Richter, K. (Herz-Kreislaufklinik, Berlin-Buch (Germany)) (ed.)

1992-01-01

This volume offers a selection of scientific assessments and data contributed by numerous experts that were based on recent experience in various fields, which include in particular: contrast echocardiography, quantitative characterisation of myocardial tissue, filmless cardangiography, quantitative DSA, digitised luminescence radiology of the thorax, on-line computer-aided cardiac evaluations, automatic recognition of image characteristics, ROC analysis, trends in PACS development, contrast media including their influences on microcirculation, recent developments and trends of non-surgical angioplasty, newly devised stents, atherectomy, the use of excimer lasers in coronaries and other vessels and of microcoils in neuroradiology. (MG).

Zur Ätiologie und Bekämpfung der Lumpy Jaw Disease bei Kängurus

OpenAIRE

Asperger, Michael

2004-01-01

In der vorliegenden Arbeit sollten die in der veterinärmedizinischen Literatur bisher diskutierten Ursachen für LJD bei Makropoden hinsichtlich ihrer tatsächlichen Bedeutung abgeklärt und die Eignung einer formalininaktivierten, bestandsspezifischen Adsorbatvakzine zur Prophylaxe von LJD getestet werden. Da LJD eine parodontale Erkrankung darstellt, wurden auch die für Entstehung einer humanen Parodontitis prädisponierenden Faktoren mit in die Untersuchung einbezogen. Es wurden Tupferproben z...

Zur Konstruktion von ''Männlichkeit'' bei ''Ultras'' : eine empirische Untersuchung zur Fanszene in Bremen

OpenAIRE

Guth, Oliver

2014-01-01

''Männliche'' Herrschaftsstrukturen sind innerhalb der gesamten Gesellschaft stark verbreitet. Dies spiegelt sich dementsprechend auch in Fußballfanszenen wider. Diese Arbeit untersucht daher die Konstruktion von Männlichkeit bei ''Ultras'', da diese mit ihrer starken Präsens und ihren aufwendigen Choreographien in Stadien großen Einfluss vor allem auf Jugendliche haben. Ziel der Untersuchung ist es, Mechanismen innerhalb der Fanszene aufzuzeigen um somit pädagogisch zu intervenieren, damit g...

Effect of radiosynovectomy in patients with inflammatory joint disorders not caused by rheumatoid arthritis; Wirksamkeit der Radiosynoviorthese bei degenerativ-entzuendlichen und chronisch-entzuendlichen Gelenkerkrankungen

Energy Technology Data Exchange (ETDEWEB)

Kroeger, S.; Klutmann, S.; Bohuslavizki, K.H.; Clausen, M. [Universitaetskrankenhaus Eppendorf, Hamburg (Germany). Abt. fuer Nuklearmedizin; Sawula, J.A.; Brenner, W.; Henze, E. [Kiel Univ. (Germany). Klinik fuer Nuklearmedizin

1999-07-01

Aim: Effect of radiosynovectomy (RS) should be evaluated both by subjective and objective parameters in patients with osteoarthritis and in patients with inflammatory joint disorders not caused by rheumatoid arthritis. Methods: A total of 98 joints in 61 patients were investigated. Patients were divided into two groups. The first group included 35 patients with therapy-resistant effusions caused by severe osteoarthritis (46 joints). The second group consisted of 26 patients (52 joints) with ankylosing spondylitis, reactive arthritis, undifferentiated spondylarthropathy, psoriatic arthritis, pigmented villo-nodular synovitis, and recurrent synovitis following surgery. Effect of RS was evaluated by a standardized questionnaire and quantified by T/B-ratios derived from blood pool images prior to and after RS. Results: Within the first patient group suffering from osteoarthritis, 40% showed a good or excellent improvement of clinical symptoms, 51% were unchanged, and in 9% symptoms worsened. Similar results were found in the second patient group. The majority of unchanged results were small finger joints. In contrast, wrist and knee joints showed a better improvement. Good correlation between results of bone scan and patients subjective impression was found in 38% and 67% in the first and the second patient group, respectively. Conclusion: Radiosynovectomy might be an effective treatment in osteoarthritis and inflammatory joint disorders not caused by rheumatoid arthritis. (orig.) [German] Ziel: Der Therapieerfolg der Radiosynoviorthese (RSO) sollte bei aktivierter Arthrose und anderen chronisch-entzuendlichen Gelenkerkrankungen anhand der subjektiven Befindlichkeit und objektiver Parameter evaluiert werden. Methoden: Es wurden insgesamt 98 Gelenke bei 61 Patienten behandelt. Entsprechend der Grunderkrankung umfasste die erste Gruppe 35 Patienten mit einer therapieresistenten, aktivierten Arthrose (46 Gelenke). Die zweite Patientengruppe beinhaltete 26 Patienten (52

Padrões Contábeis internacionais do IASB: Um estudo comparativo com as normas contábeis brasileiras e sua aplicação

Directory of Open Access Journals (Sweden)

L. Nelson Carvalho

2009-10-01

Full Text Available Atribui-se a Jonh Kennteh Galbraith a afirmativa de que os economistas deveriam se preocupar em medir "Felicidade Nacional Bruta" do que "Produto Nacional Bruto" e que "Felicidade", objetivamente considerada , é o pai da família ou jovem em idade de trabalho a encontratem emprego e oportunidades. Isso se dá, em grande parte, por um setor empresarial empreendedor, e este mostra sua vitalidade por meio de mecanismos de comunicação que espelhem suas virtudes. O melhor, o mais clássico e universal - conquanto não é o único- mecanismo de comunicação de desempenho empresarial com credores , investidores, governo, fornecedores é o conjunto das demonstrações contábeis.

Selective embolisation of posttraumatic intractable epistaxis; Selektive Embolisation bei posttraumatisch unstillbarer Epistaxis

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Nickel, J.; Andresen, R. [Abt. fuer Diagnostische Bildgebung und Interventionelle Radiologie, Guestrower Krankenhaus (Germany); Sachs, W. [Klinik fuer Hals-Nasen-Ohrenerkrankungen, Guestrower Krankenhaus (Germany)

2003-07-01

We report on a patient who developed hemodynamically relevant epistaxis due to splanchnocranial injuries after falling from his bicycle. Spiral-CT showed a fracture of the posterior nasal septum and of the inferior nasal concha. Despite anterior and posterior nasal tamponade, anemia occurred requiring transfusion and resulting in the interdisciplinary decision to perform transcatheter embolization. Via a trans femoral incision, a 5 F Vitek catheter was introduced into the maxillary artery, and a tracker system was then advanced through the catheter supraselectively and placed in the peripheral branches of the vascular system of the sphenopalatine artery. Selective DSA clearly showed the source of bleeding to be the area supplying the sphenopalatine artery. Following documentation of the localization of bleeding, a total of six (3/30 mm) complex heliacal mini-coils were inserted. After intravascular occlusion of the sphenopalatine artery, bleeding completely stopped within a few minutes. This shows that supraselective embolization is an easily conducted, effective and low-complication method for the definitive treatment of severe posttraumatic nose-bleeds, even in emergency situations. (orig.) [German] Wir berichten ueber einen Patienten, welcher mit Eingeweideschaedelverletzungen nach Fahrradsturz eine haemodynamisch relevante Epistaxis entwickelte. In der durchgefuehrten Spiral-CT zeigte sich eine Fraktur des hinteren Nasenseptums und der Concha nasalis inferior. Trotz vorderer und hinterer Nasentamponade kam es zu einer transfusionsbeduerftigen Anaemie, so dass interdisziplinaer die Entscheidung zur Transkatheterembolisation getroffen wurde. Ueber einen transfemoralen Zugang erfolgte mit einem 5 F Vitek-Katheter der Eingang bis in die A. maxillaris, ueber den liegenden Katheter wurde dann supraselektiv ein Trackersystem bis in die peripheren Aeste des Stromgebietes der A. sphenopalatina platziert. Mittels selektiver DSA liess sich die Blutungsquelle eindeutig dem

Magnetic resonance spectroscopy of brain tumors; MR-Spektroskopie bei Hirntumoren

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Ditter, P.; Hattingen, E. [Universitaetsklinikum Bonn, FE Neuroradiologie, Radiologische Klinik, Bonn (Germany)

2017-06-15

Conventional magnetic resonance imaging (MRI) under consideration of clinical information enables the correct diagnosis and therapy for the majority of cerebral space-occupying lesions. Some important differential diagnoses, e. g. low vs. high-grade tumors, require additional MRI methods. This article critically discusses the importance of magnetic resonance spectroscopy ({sup 1}H-MRS) in brain tumors. The concentration of normal and pathological brain metabolites can be non-invasively measured by {sup 1}H-MRS. It is based on the principle that chemical proton compounds of certain brain metabolites focally attenuate the external magnetic field and change the proton resonance frequency according to typical patterns. In addition, parameter maps of MRS imaging (MRSI) can show the tumor heterogeneity as well as changes in the surrounding brain tissue. In this context, the patterns of N-acetylaspartate, total choline (tCho) and creatine are relatively robust, whereas the patterns of other metabolites, such as myoinositol, glutamate, lactate or lipids greatly depend on the external field strength and echo time. The signal intensity of tCho in vital tumor tissue increases with the WHO grade of the brain tumor, i.e. increases with the level of malignancy. The use of MRSI facilitates the WHO grading of gliomas by determining target points in biopsies. Different distribution patterns and specific metabolite signals enable a better differentiation between abscesses, metastases, central nervous system (CNS) lymphomas and gliomas. The use of {sup 1}H-MRS provides valuable information on the differential diagnosis and graduation of brain tumors; however, so far artefacts, signal strength, parameter selection and a lack of standardization impede the establishment of {sup 1}H-MRS for use in clinical routine diagnostics. (orig.) [German] Die konventionelle MRT ermoeglicht unter Beruecksichtigung klinischer Information bei einem Grossteil zerebraler Raumforderungen die richtige

The pulmonary artery does not participate in the blood supply of lung cancer: experimental and DSA study

International Nuclear Information System (INIS)

Han Mingjun; Feng Gansheng; Yang Jianyong; Su Hongying; Zhao Zhongchun

2000-01-01

Objective: To investigate whether or not the pulmonary artery participates in the blood supply of lung cancer and its change of morphology and blood flow in lung cancer. Methods: Two different colors of silicone were injected separately into the bronchial and pulmonary arteries of 33 rat models with squamous cell carcinoma of lung. The origin of blood supply of lung cancer and the morphologic change of pulmonary artery were observed under a stereo-microscope. The DSA of bronchial and pulmonary artery were performed simultaneously in 28 patients with lung cancer. Results: The pulmonary branch of rat and patients were reduced,thinned and occluded in the affected lung. The pulmonary artery did not form tumor vessel,and pulmonary blood flow and perfusion were reduced or absent in the affected area. Conclusion: The pulmonary artery did not participate in the blood supply of lung cancer. It is unreasonable to perform transcatheter chemo-embolization for lung cancer via pulmonary artery

ANALISIS RASIO ALTMAN MODIFIKASI PADA PREDIKSI KEBANGKRUTAN PERUSAHAAN PROPERTY DAN REAL ESTATE YANG TERDAFTAR DI BEI

OpenAIRE

Anita Tri Widiyawati; Supri Wahyudi Utomo; Nik Amah

2015-01-01

Penelitian ini bertujuan untuk mengetahui pengaruh rasio Altman Modifikasi terhadap prediksi kebangkrutan. Jenis penelitian ini termasuk penelitian kuantitatif. Populasi dalam penelitian ini adalah perusahaan property dan real estate yang terdaftar di BEI. Teknik pengambilan sampel menggunakan purposive sampling sehingga diperoleh sampel sejumlah 32 perusahaan property dan real estate yang menerbitkan laporan keuangannya selama tahun 2011-2013. Teknik analisis data menggunakan regresi logisti...

MR of the liver in Wilson`s disease; MRT der Leber bei Morbus Wilson

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Vogl, T.J. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Steiner, S. [Klinikum Grosshadern, Radiologische Klinik und Poliklinik, Univ. Muenchen (Germany); Hammerstingl, R. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Schwarz, S. [Klinikum Grosshadern, Neurologische Klinik, Univ. Muenchen (Germany); Kraft, E. [Klinikum Grosshadern, Neurologische Klinik, Univ. Muenchen (Germany); Weinzierl, M. [Klinikum Grosshadern, 2. Medizinische Klinik, Univ. Muenchen (Germany); Felix, R. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany)

1994-01-01

To show that Wilson`s disease is one likely cause of multiple low-intensity nodules of the liver we obtained MR images in 16 patients with clinically and histopathologically confirmed Wilson`s disease. Corresponding to morphological changes MRI enabled the subdivision of the patients into two groups. Using a T{sub 2}-weighted spin-echo sequence (TR/TE=2000/45-90) liver parenchyma showed multiple tiny low-intensity-nodules surrounded by high-intensity septa in 10 out of 16 patients. 5 patients had also low-intensity nodules in T{sub 1}-weighted images (TR/TE=600/20). In patients of this group histopathology revealed liver cirrhosis (n=7) and fibrosis (n=2). Common feature of this patient group was marked inflammatory cell infiltration into fibrous septa, increase of copper concentration in liver parenchyma and distinct pathological changes of laboratory data. In the remaining 6 patients no pathological change of liver morphology was demonstrated by MRI corresponding to slight histopathological changes of parenchyma and normal laboratory data. As low-intensity nodules surrounded by high intensity septa can be demonstrated in patients with marked inflammatory infiltration of liver parenchyma MRI may help to define Wilson patients with poorer prognosis. In patients with low-intensity nodules of the liver and unknown cause of liver cirrhosis laboratory data and histopathology should be checked when searching for disorders of copper metabolism. (orig.) [Deutsch] Im Rahmen einer prospektiven Studie wurde die Leber bei 16 Patienten mit klinisch gesichertem Morbus Wilson magnetresonanztomographisch untersucht. Zum Einsatz kamen T{sub 1}- und T{sub 2}-gewichtete Spin-Echo-Sequenzen vor und nach Applikation von Gd-DTPA (0,1 mmol/kg KG). Anhand der MRT-Befunde konnten zwei unterschiedliche Patientenkollektive definiert werden. 10 Patienten wiesen in der T{sub 2}-gewichteten Sequenz hypointense Regeneratknoten auf und zeigten histopathologisch ausgepraegte Befunde einer

Fractures of the cervical spine. Diagnostic procedures in patients with severe cranio-cervical trauma; HWS-Frakturen. Diagnostik bei polytraumatisierten Patienten

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Link, T.M. [Inst. fuer Klinische Radiologie, Univ. Muenster (Germany); Schuierer, G. [Inst. fuer Klinische Radiologie, Univ. Muenster (Germany); Hufendiek, A. [Inst. fuer Klinische Radiologie, Univ. Muenster (Germany); Peters, P.E. [Inst. fuer Klinische Radiologie, Univ. Muenster (Germany)

1994-12-01

The purpose of our study was to analyze diagnostic procedures of the cervical spine in severely traumatized patients. Findings in plain radiographs and computer radiography of 234 patients were evaluated. The image quality of the plain radiographs was examined. Casualty reports were evaluated retrospectively. Frequency, distribution and morphology of cervical spine fractures were analyzed: 44 fractures in 35 patients were diagnosed, most of the fractures were located in C2 (20/44). Twenty of the fractures diagnosed in CT were not diagnosed in plain radiography and 7 fractures were uncertain findings; 5 fractures were not detected at the casualty site. A new screening procedure in patients with severe head injury is introduced. (orig.) [Deutsch] Ziel der vorliegenden Studie war, die Diagnostik der HWS beim polytraumatisierten Patienten zu analysieren. Retrospektiv wurden Roentgenaufnahmen und Computertomogramme der HWS von 234 polytraumatisierten Patienten analysiert. Konventionelle HWS-Aufnahmen wurden in bezug auf ihre Qualitaet untersucht und der Befund der konventionellen Aufnahmen mit dem der Computertomographie verglichen. Die Befunde vom Unfalltag wurden den retrospektiv validierten Befunden gegenuebergestellt. Haeufigkeit, Verteilung und Morphologie von HWS-Frakturen bei polytraumatisierten Patienten wurden untersucht: 44 Frakturen bei 35 Patienten waren nachweisbar, am haeufigsten Frakturen von HWK 2 (21/44). 20 der Frakturen konnten konventionelle radiologisch nicht und 7 nur fraglich diagnostiziert werden. 5 Frakturen wurden am Unfalltag nicht erkannt. Ein neues Untersuchungsprotokoll mit routinemaessiger computertomographischer Untersuchung von HWK 1 und 2 bei Schaedel-Hirn-Traumata wird vorgestellt. (orig.)

Toward Electoral Security: Experiences from KwaZulu-Natal Höhere Sicherheit bei Wahlen: Erfahrungen aus KwaZulu-Natal

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Kristine Höglund

2011-01-01

Full Text Available There is a growing recognition of the dangers of electoral violence. Yet, the theoretical foundation for systematic research and for adequate policy is still underdeveloped. This article aims to develop the theoretical understandings of strategies to manage and prevent electoral violence. This is accomplished by integrating research conducted within the two academic discourses on democratization and conflict management and also by drawing on the experiences from the conflict-ridden province KwaZulu-Natal in South Africa. The five strategies identified are monitoring, mediation, legal measures, law enforcement and self-regulating practices. In the article, the functions and mechanisms of the strategies are discussed. In addition, we analyse the limitations and usefulness of each of the strategies in turn and also provide suggestions on how to improve electoral security.Gewaltsame Auseinandersetzungen bei Wahlen werden zunehmend als Gefahr erkannt. Dennoch sind die theoretischen Grundlagen systematischer Forschungen zu diesem Phänomen, die zu angemessenen politischen Handlungsweisen beitragen könnten, immer noch ungenügend entwickelt. Dieser Beitrag zielt darauf ab, einen theoretischen Hintergrund für Strategien zum Umgang mit Gewalt bei Wahlen und zur Prävention zu entwickeln. Zu diesem Zweck kombinieren die Autorinnen Ergebnisse zweier Forschungsbereiche – der Demokratisierungsforschung und der Forschung zum Konfliktmanagement – und ziehen außerdem Erfahrungen aus der konfliktbeladenen südafrikanischen Provinz KwaZulu-Natal heran. Sie identifizieren fünf Strategien: Monitoring, Mediation, gesetzliche Maßnahmen, Sanktionierung und Selbsthilfepraktiken. Die Autorinnen diskutieren die Wirkungsweisen und Erfolgsaussichten, aber auch die Grenzen dieser Strategien und machen einige konkrete Vorschläge zur Erhöhung der Sicherheit bei Wahlen.

[Osteopathie bei gastroösophagealem Reflux mit Hiatushernie: Ein Fallbericht gemäß der CARE-Leitlinie].

Science.gov (United States)

Rotter, Gabriele; Brinkhaus, Benno

2017-01-01

Hintergrund: Das Vorhandensein einer Hiatushernie kann das Auftreten einer gastroösophagealen Refluxerkrankung (GERD) als Komplikation bedingen. Konventionelle medizinische Therapiemaßnahmen können zu unerwünschten Ereignissen und Rezidiven führen. Bisher sind die Effekte von osteopathischen Behandlungen bei Hiatushernie und GERD nicht bekannt. Fallbericht: Eine 59-jährige Patientin mit endoskopisch diagnostizierter chronischer Gastritis, GERD und Hiatushernie beklagte einen persistierenden gastroösophagealen Reflux trotz konventionell-medizinischer konservativer Therapie. Die osteopathische Diagnostik ergab eine funktionelle Störung im Bereich des Magens und der Kardia mit einer Beteiligung zugehöriger Reflexzonen. Nach einer osteopathischen Behandlung als individuelle, befundorientierte Therapie ließen die Beschwerden erheblich nach. Die Hiatushernie war nach einer dieser Behandlung endoskopisch nicht mehr nachweisbar. Schlussfolgerungen: Dieser Fallbericht schildert die Symptomreduktion einer GERD nach osteopathischer Behandlung. In der endoskopischen Folgeuntersuchung fand sich die initial diagnostizierte Hiatushernie nicht mehr, diese Befund änderung könnte jedoch auf die unterschiedlichen Untersucher zurückgeführt werden. Prospektive kontrollierte klinische Studien sind notwendig, um den Stellenwert von osteopathischen Behandlungen bei GERD mit Hiatushernie zu untersuchen. © 2017 The Author(s). Published by S. Karger GmbH, Freiburg.

MR-guided biopsies of undetermined liver lesions: technique and results; MRT-gezielte perkutane Biopsie bei unklaren fokalen Leberlaesionen: Technik und Ergebnisse

Energy Technology Data Exchange (ETDEWEB)

Zangos, S.; Kiefl, D.; Eichler, K.; Engelmann, K.; Heller, M.; Herzog, C.; Mack, M.G.; Jacobi, V.; Vogl, T.J. [Inst. fuer Diagnostische und Interventionelle Radiologie, Johann-Wolfgang-Goethe-Univ. Frankfurt (Germany)

2003-05-01

Purpose: To evaluate safety and precision of liver tumor biopsies performed in an open low field system using different sequence techniques. Materials and Methods: In 47 patients with liver tumors, MR-guided biopsies were performed in a low field system (0.2 Tesla, Magnetom Open, Siemens) using two different sequences. The procedure was monitored with T1-weighted FLASH sequences (TR/TE = 100/9; 70 ) in all patients and with FISP-Rotated-Keyhole-sequence (TR/TE = 18/8; 90 ) in additional 20 patients. After positioning of the needle tip in the tumors, 166 biopsy specimens were acquired with 16 G cutting needles (Somatex{sup *}). The diameter of the biopsied lesions ranged from 1 to 10 cm (mean diameter 3.2 cm). Visibility of the needles and precision of the biopsies were evaluated. Results: All interventional biopsies were performed without vascular or organ injuries. Adequate specimens for histologic interpretation were obtained in 42 cases (89.3%). The biopsy results were non-specific in 2 patients (4.2%) and the lesions missed in 3 patients (6.3%). Mean in-room time was 35 minutes and the intervention time was 8.3 minutes. T1-weighted FLASH images proved optimal for confirming needle-tip placement during the biopsies or punctures. Organs, tumors and vessels were easily identified. The FISP sequence proved to be inferior in visualizing vessels and tumors. Conclusion: MR-guided liver biopsies are safely and precisely performed using T1-weighted FLASH-sequences with sufficient visualization of the lesions and might be complementary to US- or CT-guided biopsies. (orig.) [German] Zielsetzung: Evaluierung der Sicherheit und Genauigkeit MRT-gezielter Leberbiopsien unter Verwendung verschiedener Sequenzen. Methoden: Bei 47 Patienten mit unklaren Leberlaesionen wurden in einem offenen 0,2-Tesla-MR-System (Magnetom Open, Siemens) bildgesteuerte Biopsien unter Verwendung von zwei verschiedenen Sequenzen durchgefuehrt. Die Bildgebung erfolgte bei allen Patienten mittels T

Comparison of Ultra-Rapid Orbit Prediction Strategies for GPS, GLONASS, Galileo and BeiDou

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Tao Geng

2018-02-01

Full Text Available Currently, ultra-rapid orbits play an important role in the high-speed development of global navigation satellite system (GNSS real-time applications. This contribution focuses on the impact of the fitting arc length of observed orbits and solar radiation pressure (SRP on the orbit prediction performance for GPS, GLONASS, Galileo and BeiDou. One full year’s precise ephemerides during 2015 were used as fitted observed orbits and then as references to be compared with predicted orbits, together with known earth rotation parameters. The full nine-parameter Empirical Center for Orbit Determination in Europe (CODE Orbit Model (ECOM and its reduced version were chosen in our study. The arc lengths of observed fitted orbits that showed the smallest weighted root mean squares (WRMSs and medians of the orbit differences after a Helmert transformation fell between 40 and 45 h for GPS and GLONASS and between 42 and 48 h for Galileo, while the WRMS values and medians become flat after a 42 h arc length for BeiDou. The stability of the Helmert transformation and SRP parameters also confirmed the similar optimal arc lengths. The range around 42–45 h is suggested to be the optimal arc length interval of the fitted observed orbits for the multi-GNSS joint solution of ultra-rapid orbits.

Clinically relevant incidental cardiovascular findings in CT examinations; Klinisch relevante kardiovaskulaere Zufallsbefunde bei CT-Untersuchungen

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Voigt, P.; Fahnert, J.; Kahn, T.; Surov, A. [Universitaetsklinikum Leipzig, Klinik fuer Diagnostische und Interventionelle Radiologie, Leipzig (Germany); Schramm, D.; Bach, A.G. [Universitaetsklinikum Halle (Saale), Klinik fuer Radiologie, Halle (Germany)

2017-04-15

Incidental cardiovascular findings are a frequent phenomenon in computed tomography (CT) examinations. As the result of a dedicated PubMed search this article gives a systemic overview of the current literature on the most important incidental cardiovascular findings, their prevalence and clinical relevance. The majority of incidental cardiovascular findings are of only low clinical relevance; however, highly relevant incidental findings, such as aortic aneurysms, thromboses and thromboembolic events can also occasionally be found, especially in oncology patients. The scans from every CT examination should also be investigated for incidental findings as they can be of decisive importance for the further clinical management of patients, depending on their clinical relevance. (orig.) [German] Inzidentelle kardiovaskulaere Befunde sind ein haeufiges Phaenomen bei CT-Untersuchungen. Mit dieser Arbeit soll nach gezielter PubMed-Recherche ein systematischer Literaturueberblick ueber die wichtigsten kardiovaskulaeren Zufallsbefunde sowie deren Haeufigkeit und klinische Relevanz gegeben werden. Die Mehrzahl der inzidentellen kardiovaskulaeren Befunde sind klinisch nur von untergeordneter Bedeutung, allerdings werden immer wieder auch hochgradig relevante Zufallsbefunde wie beispielsweise Aortenaneurysmata oder - gerade bei onkologischen Patienten - Thrombosen und thrombembolische Ereignisse detektiert. Jede CT-Untersuchung sollte gezielt nach inzidentellen Befunden durchsucht werden, da diese je nach klinischer Relevanz von entscheidender Bedeutung fuer das weitere klinische Management des Patienten sein koennen. (orig.)

Os controles internos e contábeis na gestão de tesouraria

OpenAIRE

Pereira, Marcos Augusto Assi

2010-01-01

As atividades de Controles Internos e Contábeis fazem parte da gestão do negócio, mas ainda existe muita dificuldade no entendimento da aplicabilidade da matéria seja por ignorância dos benefícios, seja pela ausência de cultura de controle. Essas atividades exigem multiplicidade de conhecimentos de gestão, controle e governança corporativa, além da permanente atualização profissional. O controle contábil é derivado do controle interno, que determina as políticas e procedi...

EXCESS CASH HOLDINGS DAN KEPEMILIKAN INSTITUSIONAL PADA PERUSAHAAN MANUFAKTUR YANG TERDAFTAR DI BEI

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Yessica Tria Christina

2014-02-01

Full Text Available This research provides an empirical evidence about the effect of institutional ownerships as a proxy of information transparancy on excess cash holdings. Manufacture companies listed on BEI from years 2002 to 2011 are employed. The results show that the higher the proportion of institutional ownership, the lower the excess cash holdings. Informational transparancy, as one of the requirements of good corporate governance, can in fact lower the chance of aggrevating the manager’s behavior to practice excess cash holdings that can lower the company’s efficiency.

Komplexitätsbeherrschung in der wertschöpfungspartnerschaftsübergreifenden Produktspezifikationserstellung bei unvollkommenen Informationen durch Simplifizierungsregeln

OpenAIRE

Ludwig, Ralf

2005-01-01

Probleme/Forschungsfragen: Ein stetiger Komplexitätsanstieg des Produktes und der Produktentwicklungsumgebung erschweren in Wertschöpfungspartnerschaften das Erreichen einer gemeinsamen Win-Win-Situation. Bei der frühen Erarbeitung der Produktauslegung oder im Rahmen der Produktspezifikationserstellung ist durch die hohe Komplexität von Entwicklungsaufgabe und -umgebung eine umfassende gesamtheitliche Berücksichtigung der wirtschaftlichen Erfolgsdeterminanten nur sehr begrenzt möglich. Ein...

Anwendung des Traumatherapieverfahrens -Narrative Expositionstherapie- bei komplex traumatisierten Patienten unter besonderer Berücksichtigung des Schlafes

OpenAIRE

Scharff, Anna-Lena

2016-01-01

Die Studie sollte aufgrund der häufigen Komorbidität einer Posttraumatischen Belastungsstörung mit der Borderline Persönlichkeitsstörung die Frage untersuchen, ob die Narrative Expositionstherapie einen Therapieerfolg bei komplex traumatisierten Patienten hat. Desweiteren sollte der Effekt der Therapie auf den Schlaf untersucht werden und eventuell prädiktive Zusammenhänge zwischen Schlafqualität und Therapieerfolg herausgestellt werden.

Desempenho acadêmico em métodos quantitativos nos cursos de Ciências Contábeis

Directory of Open Access Journals (Sweden)

Manoel Raimundo Santana Farias

2015-08-01

Full Text Available Este estudo investigou variáveis que explicam o desempenho acadêmico (academic achievement nas disciplinas de métodos quantitativos no curso de ciências contábeis. Realizou-se uma pesquisa empírica na Universidade Federal do Pará com objetivo de encontrar proxies associadas à variável dependente desempenho acadêmico. Assim, com a finalidade de ratificar os achados desta pesquisa, foi realizado teste estatístico de análise de regressão por meio do software SPSS®. A análise inferencial conjecturou oito variáveis que explicariam o desempenho dos discentes, quais sejam: desempenho anterior em matemática e/ou estatística, índice de participação do discente na realização das disciplinas, turno de estudo, idade, gênero, estado civil, possuir ou não renda e origem escolar. Após a realização da análise de regressão com essas variáveis, o modelo mais adequado para representação do desempenho dos discentes foi o que considerou apenas as seguintes variáveis: desempenho anterior em matemática e/ ou estatística, índice de participação do discente na realização das disciplinas, o turno de estudo e a idade, as quais apresentaram significância estatística. Esses resultados ratificam que características pessoais determinam o desempenho de discentes de ciências contábeis, como afirmado por Santos (2012, referenciada neste estudo. Futuras pesquisas podem ratificar as variáveis aqui trabalhadas e expandir tal estudo a fim de obter um modelo mais representativo sobre o desempenho dos discentes em métodos quantitativos nos cursos de ciências contábeis.

Migration measurement of acetabular components in cementless total hip arthroplasty; Messung der Pfannenwanderung bei zementfreien Hueftimplantaten

Energy Technology Data Exchange (ETDEWEB)

Eckardt, A.; Karbowski, A.; Schwitalle, M.; Vogel, J.; Boden, F.; Seeleitner, C. [Mainz Univ. (Germany). Orthopaedische Klinik und Poliklinik; Schunk, K. [Mainz Univ. (Germany). Klinik und Poliklinik fuer Radiologie; Mayrhofer, P. [Innsbruck Univ. (Austria). Inst. fuer Mathematik und Geometrie

1998-08-01

Migration measurements of acetabular components using a special computer aided method (EBRA = abbrevation for the German term ``Ein-Bild-Roentgenanalyse``) were performed to evaluate early results of the implants and predict aseptic loosening. Methods: Standard ap-radiographs of the pelvis were marked, specific points were digitised. Simulating the spatial situation the programme computes lengitudinal and vertical migration of the cup. 74 acetabular components in 71 patients could be studied by migration measurements. Results: 14 patients showed migration of more than 1 mm, which is the confidence limit of this method. Each of these patients showed diverse reasons for the migration, i.e. osteoporosis of the acetabular bone stock or problems concerning the surgical technique which means malposition of the cup or insufficient reaming of the bone. There were some patients with severe congenital dysplasia of the hip and in some cases the inclination angle of the cup was too great. Conclusion: The technique applied for measuring migration of acetabular components can be useful for evaluating early instability of the implant and can be helpful in detecting problems concerning the surgical technique. (orig.) [Deutsch] Mittels der Ein-Bild-Roentgenanalyse wurden Pfannenwanderungen nach Implantation von zementfreien, sphaerischen Hueftgelenkspfannen erfasst, um Praediktoren fuer die langfristige Prognose der Implantate zu evaluieren. Methoden: Nach Markierung von Referenzpunkten in den Beckenuebersichtsaufnahmen wurden diese digitalisiert, vom Programm verrechnet und die Wanderung des Implantats im Verlauf angegeben. Bei 71 Patienten wurden von 74 Pfannen ueber einen Mindestnachuntersuchungszeitraum von 12 Monaten Migrationsmessungen durchgefuehrt. Das Konfidenzintervall der Methode liegt bei <1 mm. Bei jedem dieser Patienten fanden sich Hinweise entweder auf ein schlechtes Knochenlager, auf operationsbedingte Probleme, wenn keine ausreichende Primaerstabilitaet der Pfanne

Multimodal diagnosis of multiple and heterogeneous liver lesions in a young patient; Multimodale Bildgebung multipler Leberlaesionen bei einem jungen Patienten

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Kiessling, F.; Schlemmer, H.-P. [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg (Germany). Abteilung fuer onkologische Diagnostik und Therapie

2005-10-01

The classification of liver lesions is often problematic in particular if they are multiple and show an heterogeneous shape. Here we report of a young patient with multiple liver lesions of up to 3 cm size. Using ultrasound, the lesions were hyper-, hypoechogen or mixed. In serial contrast enhanced CT scans some of the lesions showed the typical enhancement pattern of hemangiomas, however, the diagnosis could still not be faithfully determined for all lesions. Therefore, the patient was conducted to contrast enhanced MRI (Gd-DTPA and MnDPDP). While with Gd-DTPA some of the lesions showed a strong enhancement, they remained hypointense after administration of MnDPDP. Finally to exclude a metastatic disease a {sup 99m}Tc-erythrocyte SPECT was performed confirming the diagnosis of hemangiomas for most of the lesions. Diagnosis was not assessed by biopsy because this would only clarify the diagnosis for one or few of the lesions. The patient was subsequently followed up for 3 years and all lesions remained unchanged. This case clearly illustrates the difficulty to get a certain diagnosis of multiple liver lesions with heterogeneous appearance despite the multimodal diagnostic conduct. (orig.) [German] Bei einer Routineuntersuchung wurden bei einem jungen Patienten sonographisch multiple Leberrundherde mit hyper-, hypoechogener und gemischter Echogenitaet detektiert. Auch mittels triphasischer kontrastmittelverstaerkter CT gelang nur bei einem Teil der Herde die Einstufung als Haemangiome anhand ihres Irisblendenphaenomens. MRT-Untersuchungen unter Verwendung von Gd-DTPA und MnDPDP wurden angeschlossen. Mit Gd-DTPA zeigten einige Herde ein kraeftiges Enhancement, unter Verwendung von MnDPDP jedoch blieben sie hypointens. Auf eine Biopsie wurde verzichtet, da diese nur bei einem oder wenigen Herden die Diagnose liefern wuerde, die anderen Herde aber unter Beruecksichtigung ihrer Heterogenitaet unklar geblieben waeren. Eine Sicherung der Diagnose gelang fuer die meisten

Clinical implications of a new TSH-receptor-antibody-assay (DYNOtest {sup trademark} TRAKhuman) in autoimmune thyroid diseases; Klinische Implikationen eines neuen TSH-Rezeptor-Antikoerper-Assays (DYNOtest {sup trademark} TRAKhuman) bei autoimmunen Schilddruesenerkrankungen

Energy Technology Data Exchange (ETDEWEB)

Meller, J.; Schreivogel, I.; Becker, W. [Goettingen Univ. (Germany). Abt. fuer Nuklearmedizin; Bergmann, A.; Morgenthaler, N. [B.R.A.H.M.S Diagnostica, Berlin (Germany); Huefner, M. [Goettingen Univ. (Germany). Abt. Innere Medizin

2000-07-01

Aim: Conventional radioreceptor-antibody-assays (RAAs) fail in the detection of TSH-receptor antibodies (TRAKs) in 10-30% of patients with Graves' disease (GD). The aim of this study was the evaluation of the diagnostic and clinical impact of a new RRA (DYNOtest {sup trademark} TRAKhuman) which uses the human recombinant TSH-Receptor in the diagnosis of autoimmune thyroid disease. Methods: Sera from 142 consecutive patients (GD: n=50, autoimmune thyroiditis/AIT: n=92) and from 55 controls (31 patients without any thyroid disease and 14 with euthyroid goiter) were evaluated both with the DYNOtest {sup trademark} TRAKhuman-assay and a conventional RRA (TRAK-Assay {sup trademark}). Thyroid in vitro parameters and thyroid sonography were performed in all patients. Results: The DYNOtest {sup trademark} TRAK-assay was significantly superior to the conventional RRA in the diagnosis of GD (p<0,00012), especially in those who were treated by thionamides (p<0,003) and in the diagnosis of TRAK-positive patients with AIT (p<0,003). The majority of TRAK-positive AIT-patients suffered from hypothyroidism. One false positive result in patients with euthyroid goiter was found in the TRAK-Assay {sup trademark} as well as in the DYNOtest {sup trademark} TRAKhuman-Assay. Therefore the specifity of the DYNOtest {sup trademark} TRAKhuman was not inferior compared with the conventional assay. Conclusion: The DYNOtest {sup trademark} TRAK-assay is superior in the diagnostic work up of Graves' disease compared with a conventional TRAK-assay and offers an equal specifity. (orig.) [German] Ziel: Bei konventionellen Radiorezeptor-Antikoerper-Assays (RRAs) misslingt der Nachweis von TSH-Rezeptor Antikoerpern (TRAKS) bei 10-30% der immunogenen Hyperthyreosen (IH). Ziel der Studie war es, den diagnostischen und klinischen Stellenwertes eines neuen RRA (DYNOtest {sup trademark} TRAKhuman) bei autoimmunen Schilddruesenerkrankungen zu evaluieren. Methoden: Serumproben von 142

Passado, presente e futuro dos princípios contábeis norte-americanos - US GAAP Lições para contabilidade brasileira

Directory of Open Access Journals (Sweden)

João Henrique Pederiva

2009-10-01

Full Text Available Como se estruturam as normas contábeis adotadas para registrar as atividades econômicas norte-americanas - United States Generally Accepted Accounting Principles - US GAAP (Princípios Contábeis Geralmente Aceitos Norte Americanos, quais os seus principais eixos de desenvolvimento doutrinário e que interesse há nesse conhecimento para a contabilidade brasileira? A relevância de obter respostas a esses questionamentos resulta da importância econômica dos Estados Unidos da America para as demais nações. Afinal, os recentes problemas nos mercados de capitais norte-americanos comprometeram, em dois anos e meio, US$ 7,7 trilhões da poupança destinada a aposentadoria dos trabalhadores daquele país. Atente-se que muitos países, inclusive o Brasil, buscam recursos nesses mercados de capitais.

Suche nach Charginos in 4 Jet Ereignissen bei LEP2

CERN Document Server

AUTHOR|(CDS)2086503

1997-01-01

Zum heutigen Tag sind der Hochenergiephysik einige Hundert Teilchen und Teilchenzustände bekannt, die dem Anschein nach auf sehr komplexe Weise wechselwirken und so die beobachtbare Welt konstituieren. Bei näherer Betrachtung sind jedoch nur wenige Teilchen und Wechselwirkungen elementar, in dem Sinne, dass die übrigen sich als aus ihnen zusammengesetzt ansehen lassen. Die Frage, wie man diese elementaren Teilchen und ihre fundamentalen Wechselwirkungen systematisch beschreiben kann, beantwortet das Standardmodell der Elementarteilchenphysik. Es verwendet das Spektrum der fundamentalen Materie, die inneren Symmetrieeigenschaften dieses Spektrums und das Eichprinzip, um eine Beschreibung im Rahmen der Quantenfeldtheorie zu formalisieren. Das Standardmodell leistet so eine prinzipielle Beschreibung der bis heute betrachteten Hochenergiephysik. Dabei treten allerdings einige Probleme auf, die es attraktiv erscheinen lassen, das Standardmodell um eine weitere Symmetrieeigenschaft zu erweitern, nämlich um die ...

Logfile-Analysen: Möglichkeiten und Grenzen ihrer Nutzung bei Untersuchungen zur Mensch-Maschine-Interaktion

Directory of Open Access Journals (Sweden)

Burkhard Priemer

2004-06-01

Full Text Available Die Aufzeichnung der Computernutzung in automatisch generierten elektronischen Protokollen – so genannten Logfiles – entwickelt sich zu einer zunehmend genutzten Erfassungsmethode bei Untersuchungen der Interaktion zwischen Mensch und Computer. Dieser Beitrag bietet einen einführenden Überblick über Verfahren der Logfile-Aufzeichnung und der Analyse der Daten. Neben einer Erläuterung der Begrifflichkeiten werden sowohl Vor- und Nachteile von Logfile-Auswertungen als auch grundlegende Methoden, mathematische Beschreibungen des Nutzerverhaltens und Ansätze der Typisierung von Nutzeraktivitäten dargestellt.

Capability of a SOFC-APU to optimise the fuel consumption of motor vehicles; Potenzial einer SOFC-APU bei der Verbrauchsoptimierung von Kraftfahrzeugen

Energy Technology Data Exchange (ETDEWEB)

Diegelmann, Christian B.

2008-04-28

recuperating function) and in numerous driving cycles. The evaluated SOFC-APU has a nominal power of 1.5 kW (orig.) [German] Bei der Analyse des Energiesystems Kraftfahrzeug werden in dieser Arbeit verschiedene Anwendungsmoeglichkeiten einer SOFC-APU (Auxiliary Power Unit) zur Reduktion des Kraftstoffverbrauchs identifiziert. Neben der reinen Stromversorgung kann die APU Funktionen wie Motor- Stopp-Automatik (MSA) oder elektrisches Fahren (Hybridfahrzeug) unterstuetzen. Des weiteren erzeugt eine SOFC-APU Abwaerme auf einem hohen Temperaturniveau. Die Abwaerme kann zum Heizen des Fahrgastraums oder zur Vorwaermung des Verbrennungsmotors verwendet werden. Fuer die Bewertung der Einsparpotenziale wurden mehrere Methoden betrachtet. Eine einfache Abschaetzung des Kraftstoffverbrauchs ueber mittlere Wirkungsgrade und Leistungen ist bereits ausreichend, um die Haupteinfluesse zu identifizieren und zu bewerten. Die Einsparpotenziale einer SOFC-APU haengen in erster Linie von drei Faktoren ab, dem Startup-Verbrauch der APU, der Betriebsdauer und der angeforderten elektrischen Leistung. Eine kalte APU muss zunaechst auf eine Betriebstemperatur von 700 C bis 800 C erwaermt werden. Dieser Aufheizvorgang benoetigt Energie, so dass zunaechst ein Mehrverbrauch besteht. Erst nach laengerer Betriebsdauer kompensiert sich dieser Mehrverbrauch durch die hohe Effizienz der SOFC-APU. Die Dauer ist stark abhaengig von der elektrischen Leistung. Bei hoeherer elektrischer Leistung besteht prinzipiell eine hoehere Einsparrate durch die APU. Besonders interessant ist eine APU bei Standanwendungen mit hohem Energiebedarf, da hier durch die APU ein Betrieb des Verbrennungsmotors im extremen Teillastbereich vermieden wird. Bei einer 30-minuetigen Standklimatisierung koennen so z.B. Kraftstoffeinsparung von ca. 36 % erreicht werden, inklusive Startup-Verbrauch. Waehrend der Fahrt sind Einsparpotenziale beim Kraftstoffverbrauch nur bei betriebsbereiter APU oder bei laengerer Betriebsdauer zu erwarten. Der

Long-term follow up MRI in children with severe head injury; Kernspintomographische Verlaufskontrolle bei Kindern nach Schaedel-Hirn-Trauma

Energy Technology Data Exchange (ETDEWEB)

Dinter, D.; Schmidt, B.; Neff, K.W.; Georgi, M. [Heidelberg Univ., Mannheim (Germany). Fakultaet fuer Klinische Medizin; Koelfen, W. [Elisabeth-Krankenhaus, Rheydt (Germany). Paediatrische Klinik; Freund, M.C. [Universitaetsklinik fuer Radiodiagnostik, Innsbruck (Austria)

1999-10-01

Purpose: A prospective study was initiated for the correlation of the findings in the initial cranial CT with the long-term follow-up MRI in children with severe head injury. Another aim was the evaluation of frequency and location of lesions, found only in MRI. Methods: 70 children with severe head injury and initially performed pathological CCT were followed up (mean time 3 years) by MRI. Results: 71% of the children had a pathological MRI. In 43% of the children with subdural bleeding could be found parenchymal lesions in the underlying cortex. All 15 children with epidural bleeding had unsuspicious findings at the former hematoma. All of the contusions were found as parenchymal residual lesions. 44% of the children had evidence of parenchymal lesions in the follow-up MRI initially and retrospectively not revealable. 16 lesions in the corpus callosum were only revealed by MRI. Conclusion: This study shows the higher sensitivity of magnetic resonance imaging in non-hemorrhagic parenchymal lesions and in 'diffuse axonal injury'. A MRI-examination is recommended in children with severe head injury, especially in patients with normal CCT and posttraumatic neurological deficits. (orig.) [German] Fragestellung: Im Rahmen einer prospektiven Studie wurden die Befunde initial durchgefuehrter Computertomographien bei Kindern mit schwerem SHT mit den Ergebnissen einer MR-Nachuntersuchung korreliert und zusaetzlich eine Evaluation der Haeufigkeit und Lokalisation ausschliesslich kernspintomographisch nachweisbarer Laesionen durchgefuehrt. Methodik: 70 Kinder mit initial nach SHT durchgefuehrtem und pathologischem CT wurden im Rahmen eines Follow-up im zeitlichen Abstand von durchschnittlich 3 Jahren kernspintomographisch nachuntersucht. Ergebnisse: Bei 71% der nachuntersuchten Kinder konnten pathologische MRT-Befunde erhoben werden. 43% der Kinder mit einer subduralen Blutung wiesen kortikal, der ehemaligen Blutung anliegende, Parenchymlaesionen auf, dagegen

Beschreibung des Korngrößenwachstums bei der Wirbelschicht-Sprühgranulation mittels statistischer Modelle

OpenAIRE

Schinzinger, Oliver

2004-01-01

Ein wichtiger Schritt bei der Herstellung von Tabletten ist die Aufarbeitung eines meist sehr feinen, schlecht fließfähigen Pulvers zu einem besser fließenden Granulat. Da die Granulation aus den drei Teilprozessen Mischen, Granulieren und Trocknen besteht, werden heutzutage Granulationen in der Wirbelschicht durchgeführt. Eine Wirbelschichtapparatur vereint die drei Teilprozesse in einem Gerät. Die Wirbelschichtgranulation wird durch eine große Anzahl an Parametern beeinflusst, die in Prozes...

Importância das informações contábeis nas unidades de negócio: estudo exploratório em uma empresa de Jaraguá do Sul

OpenAIRE

Bruch, Ilario

2005-01-01

O presente trabalho tem como objetivo analisar a importância de informações contábeis, claras e precisas, disponíveis para as unidades estratégicas de negócios na tomada de decisões administrativas. Como as unidades de negócio são, teoricamente, em menor ou maior grau, autônomas em se tratando de gerenciamento de lucros, despesas e investimentos, é fundamental que seus gestores e executivos tenham acesso a informações contábeis precisas e detalhadas, com linguagem acessiva e co...

Die Verwendung von Isoenzym-Polymorphismen - eine Herausforderungen bei der Züchtung neuer Baldriansorten (Valeriana officinalis L. s.l.

Directory of Open Access Journals (Sweden)

Penzkofer, Michael

2014-09-01

Full Text Available Mit Hilfe von Isoenzym-Polymorphismen sollte versucht werden, biochemische Unterschiede (Fingerprint zwischen verschiedenen Baldrianherkünften darzustellen, um im Anschluss diejenigen Individuen zu finden, die durch Kreuzung und nicht durch Selbstung entstanden sind. Bei Baldrian konnte für diese Methode kein Verfahrensprotokoll etabliert werden, womit auch eine Untersuchung von Kreuzungsnachkommen nicht erfolgte.

Quantitative analysis of artifacts in 4D DSA: the relative contributions of beam hardening and scatter to vessel dropout behind highly attenuating structures

Science.gov (United States)

Hermus, James; Szczykutowicz, Timothy P.; Strother, Charles M.; Mistretta, Charles

2014-03-01

When performing Computed Tomographic (CT) image reconstruction on digital subtraction angiography (DSA) projections, loss of vessel contrast has been observed behind highly attenuating anatomy, such as dental implants and large contrast filled aneurysms. Because this typically occurs only in a limited range of projection angles, the observed contrast time course can potentially be altered. In this work, we have developed a model for acquiring DSA projections that models both the polychromatic nature of the x-ray spectrum and the x-ray scattering interactions to investigate this problem. In our simulation framework, scatter and beam hardening contributions to vessel dropout can be analyzed separately. We constructed digital phantoms with large clearly defined regions containing iodine contrast, bone, soft issue, titanium (dental implants) or combinations of these materials. As the regions containing the materials were large and rectangular, when the phantoms were forward projected, the projections contained uniform regions of interest (ROI) and enabled accurate vessel dropout analysis. Two phantom models were used, one to model the case of a vessel behind a large contrast filled aneurysm and the other to model a vessel behind a dental implant. Cases in which both beam hardening and scatter were turned off, only scatter was turned on, only beam hardening was turned on, and both scatter and beam hardening were turned on, were simulated for both phantom models. The analysis of this data showed that the contrast degradation is primarily due to scatter. When analyzing the aneurysm case, 90.25% of the vessel contrast was lost in the polychromatic scatter image, however only 50.5% of the vessel contrast was lost in the beam hardening only image. When analyzing the teeth case, 44.2% of the vessel contrast was lost in the polychromatic scatter image and only 26.2% of the vessel contrast was lost in the beam hardening only image.

Receptor imaging of schizophrenic patients under treatment with typical and atypical neuroleptics; Nuklearmedizinische Rezeptordiagnostik bei schizophrenen Patienten unter Therapie mit typischen und atypischen Neuroleptika

Energy Technology Data Exchange (ETDEWEB)

Dresel, S.; Tatsch, K. [Klinik und Poliklinik fuer Nuklearmedizin der Ludwig-Maximilians-Univ. Muenchen (Germany); Meisenzahl, E. [Psychiatrische Klinik der Ludwig-Maximilians-Univ. Muenchen (Germany); Scherer, J. [Bezirkskrankenhaus Haar (Germany)

2002-09-01

-motorische Nebenwirkungen hervorzurufen. Die Besetzung postsynaptischer Dopamin-D2-Rezeptoren wird als ein wesentlicher Aspekt der antipsychotischen Wirksamkeit der Neuroleptika angesehen. Diese koennen nuklearmedizinisch durch [I-123]IBZM-SPECT dargestellt werden. Fuer das typische Neuroleptikum Haloperidol wurde eine dosisabhaengige, exponentielle Besetzung der Dopamin-D2-Rezeptoren nachgewiesen. Ab einem Schwellenwert des spezifischen Bindungsindex von 0,4 (Norm: >0,95) zeigten mit einer Ausnahme alle untersuchten Patienten extrapyramidal-motorische Nebenwirkungen. Auch unter Therapie mit dem atypischen Neuroleptikum Clozapin ergab sich eine exponentielle Dosis-Wirkungsbeziehung mit jedoch einem deutlich flacheren Kurvenverlauf im Vergleich zu Haloperidol. Extrapyramidalmotorische Nebenwirkungen traten bei diesen Patienten nicht auf. Neuere, als atypisch eingestufte Neuroleptika wie Risperidon und Olanzapin zeigten ebenfalls eine exponenzielle Dosis-Wirkungsbeziehung, wobei deren Kurvenverlaeufe zwischen denen von Haloperidol und Clozapin lagen. Extrapyramidal-motorische Nebenwirkungen traten bei den letzteren Neuroleptika seltener als bei Haloperidol, bei Olanzapin nur bei einem Patienten in unserem eigenen Patientengut auf. Das pharmakologische Profil atypischer Neuroleptika zeichnet sich neben der Bindung an die postsynaptischen Dopamin-D2-Rezeptoren auch durch Bindung an Rezeptoren diverser anderer Neurotransmittersysteme, insbesondere des serotonergen Systems, aus. Somit ist wahrscheinlich, dass die niedrigere Inzidenz fuer extrapyramidal-motorische Nebenwirkungen bei atypischen Neuroleptika durch (orig.)

Konzepte und Methoden zur Qualitätssicherung bei der Produktion von hypertextuellen Online-Lernumgebungen

Directory of Open Access Journals (Sweden)

Christian Swertz

2002-04-01

Full Text Available Die didaktische Ontologie der Webdidaktik ermöglicht die Qualitätssicherung von Prozessen und Ergebnissen bei der Produktion von Online- Lernumgebungen. Die Qualität wird durch die am pädagogischen Prozess beteiligten Menschen bestimmt. Der Qualitätssicherungsprozess kann durch Software unterstützt werden. Für diese Prozesse der Qualitätssicherung bringt der Autor Beispiele aus dem Lerndorf (www.lerndorf.de und der Lernumgebung des von der Deutschen Bundesstiftung Umwelt geförderten Forschungs- und Entwicklungsprojekt «Zentrum für Umweltwissen und Bildung» (ZUB.

Azelainsäure 20 % Creme: Auswirkung auf Lebensqualität und Krankheitsaktivität bei erwachsenen Patientinnen mit Acne vulgaris.

Science.gov (United States)

Kainz, Julius Thomas; Berghammer, Gabriele; Auer-Grumbach, Piet; Lackner, Verena; Perl-Convalexius, Sylvia; Popa, Rodica; Wolfesberger, Barbara

2016-12-01

Zur Wirksamkeit von Aknetherapien und deren Auswirkungen auf die Lebensqualität erwachsener Patienten liegen kaum Daten vor. ZIEL: Erhebung der Wirkung von Azelainsäure 20 % Creme (Skinoren ® ) auf Akne-Schweregrad und krankheitsbedingte Lebensqualität. Nichtinterventionelle Studie bei erwachsenen Patientinnen mit leichter bis mittelschwerer Akne. Wirksamkeitsparameter waren DLQI sowie Akne-Schweregrad im Gesicht, am Dekolleté sowie am Rücken im Gesamturteil des Prüfarztes (IGA-Skala: Grad 1 = annähernd reine Haut; 2 = leichte Akne; 3 = mittelschwere Akne). Visiten waren zu Studienbeginn sowie nach 4-8 und zwölf Wochen geplant. Von den 251 eingeschlossenen Patientinnen lag zu Studienbeginn bei 59 %, 31 % bzw. 10 % ein IGA-Grad von 1, 2 bzw. 3 vor; die am häufigsten betroffene Hautpartie war das Gesicht (IGA-Grad 2 oder 3: 79 %). Nach zwölf Behandlungswochen war eine signifikante Besserung der Acne vulgaris im Gesicht (IGA-Grad 0 oder 1: 82 %) sowie auf Dekolleté und Rücken feststellbar. Der mediane DLQI-Wert sank von neun zu Studienbeginn auf fünf nach zwölf Behandlungswochen. Neunzig Prozent der behandelnden Ärzte und Patientinnen beurteilten die Verträglichkeit der Behandlung als sehr gut oder gut. Die Anwendung von 20%iger Azelainsäure-Creme führt bei erwachsenen Frauen zu einer signifikanten Besserung der Acne vulgaris und der krankheitsbedingten Lebensqualität. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

Magnetic resonance imaging for ankylosing spondylitis; Magnetresonanztomographie bei ankylosierender Spondylitis (Morbus Struempell-Marie-Bechterew)

Energy Technology Data Exchange (ETDEWEB)

Bollow, M. [Augusta-Kranken-Anstalt, Inst. fuer Radiologie, Bochum (Germany)

2002-12-01

] Die ankylosierende Spondylitis (AS) gilt als Prototyp der Spondylarthropathien, welche mit einer Praevalenz von 2% zu den haeufigsten rheumatischen Erkrankungen gerechnet werden. Die Spondylarthropathie umfasst die 5 Entitaeten AS, reaktive Arthritis, Psoriasis arthropathica, enteropathische Arthritis bei Morbus Crohn und Colitis ulcerosa und die undifferenzierte Spondylarthropathie. Bei 99% der Patienten mit AS sind die ersten pathologischen Befunde an den Sakroiliakalgelenken zu finden. Die zur Diagnose einer AS geforderten Roentgenbefunde treten erst mit einer Latenz von 5-9 Jahren nach Beginn der klinischen Symptome in Erscheinung. Mit Hilfe der MRT der Sakroiliakalgelenke lassen sich sowohl chronisch-entzuendliche Veraenderungen (Erosionen, Sklerosierungen, Knochenbruecken) als auch akut-entzuendliche Veraenderungen (Synovitiden, Kapsulitiden, Osteitiden) sicher nachweisen und bezueglich ihrer Chronizitaet und Akuitaet graduieren. Enthesitiden der Ligamenta interossea des Spatium retroarticulare gehoeren zum Bild der AS. Eine Spondylodiszitis (Andersson 1937) kann als entzuendliche und als nichtentzuendliche Form (transdiskaler Ermuedungsbruch) auftreten. Zur Ankylosierung fuehrende Entzuendungen der Facetten- und der kostospinalen Gelenke sind fuer die AS typisch. Veraenderungen der Wirbelkoerper finden sich als Spondylitis anterior (Romanus 1952), posterior und marginalis. Charakteristisch fuer alle Spondylarthropathien sind darueberhinaus asymmetrische Synovitiden an den grossen Gelenken vor allem der unteren Extremitaet (Gonarthritis, Coxitis, Tarsitis, periphere Oligoarthritis), die Fibroostitis rheumatica (pelvine Enthesitis, Calcaneopathia rheumatica) und die Peri- und Synchondritiden der Symphysis pubica und der Synchondrosis sternalis. Da sich bei der AS fruehe entzuendliche Veraenderungen an der Wirbelsaeule und an den extravertebralen Manifestationsorten in der MRT vor deren Auftreten im Roentgenbild nachweisen lassen und damit die diagnostische Luecke

Neural correlates of working memory deficits in schizophrenic patients. Ways to establish neurocognitive endophenotypes of psychiatric disorders; Neuronale Korrelate gestoerter Arbeitsgedaechtnisfunktionen bei schizophrenen Patienten. Ansaetze zur Etablierung neurokognitiver Endophaenotypen psychiatrischer Erkrankungen

Energy Technology Data Exchange (ETDEWEB)

Gruber, O. [Universitaet des Saarlandes, Klinik fuer Psychiatrie und Psychotherapie, Homburg (Saar) (Germany); Max-Planck-Institut fuer Kognitions- und Neurowissenschaften, Leipzig (Germany); Gruber, E.; Falkai, P. [Universitaet des Saarlandes, Klinik fuer Psychiatrie und Psychotherapie, Homburg (Saar) (Germany)

2005-02-01

This article briefly reviews some methodological limitations of functional neuroimaging studies in psychiatric patients. We argue that the investigation of the neural substrates of cognitive deficits in psychiatric disorders requires a combination of functional neuroimaging studies in healthy subjects with corresponding behavioral experiments in patients. In order to exemplify this methodological approach we review recent findings regarding the functional neuroanatomy of distinct components of human working memory and provide evidence for selective dysfunctions of cortical networks that underlie specific working memory deficits in schizophrenia. This identification of subgroups of schizophrenic patients according to neurocognitive parameters may facilitate the establishment of behavioral and neurophysiological endophenotypes and the development of a neurobiological classification of psychiatric disorders. (orig.) [German] Dieser Beitrag befasst sich mit einigen methodischen Problemen funktionell-bildgebender Studien mit psychiatrischen Patienten, aufgrund derer die Untersuchung der neuronalen Korrelate kognitiver Defizite bei psychiatrischen Erkrankungen einer Kombination funktionell-bildgebender Studien bei gesunden Normalprobanden mit Verhaltensuntersuchungen bei Patienten bedarf. Dieser methodische Ansatz wird am Beispiel von Arbeitsgedaechtnisfunktionen erlaeutert, wobei zunaechst neuere Erkenntnisse zur funktionellen Neuroanatomie verschiedener Komponenten des menschlichen Arbeitsgedaechtnisses referiert werden. Anschliessend werden bei schizophrenen Patienten erhobene Befunde vorgestellt, die auf spezifische Stoerungen der funktionellen Integritaet neuronaler Netzwerke mit Arbeitsgedaechtnisfunktionen hinweisen. Die damit verbundene Identifikation von Subgruppen schizophrener Patienten koennte zur Etablierung verhaltensneurophysiologisch definierter Endophaenotypen psychiatrischer Stoerungsbilder fuehren und die Entwicklung einer neurowissenschaftlich

Einsatzmöglichkeiten eines Verriegelungsnagelsystems für die Katze inklusive der Bestimmung der Durchleuchtungszeiten bei der Implantation

OpenAIRE

Fiedler, Angelika Marion

2016-01-01

Im prospektiven Studienteil wurden Anwendbarkeit, Operationszeiten, Durchleuchtungseinsatz, Heilungsverlauf und Komplikationen bei der Versorgung von 25 Humerus-, Femur- und Tibiafrakturen der Katze mit dem MarMed Verriegelungsnagel(VN)-System untersucht. Die Röntgenbeurteilung fand durch 2 Beurteiler unabhängig voneinander statt. Zwischen den Beurteilern und den Wiederholungen der Knochenmessungen bestand eine sehr gute Übereinstimmung. Für Achsenabweichungen, Implantatsitz und Heilungsphase...

Erstellung eines multimedialen Lernprogramms über die Grundlagen der EKG-Aufzeichnung und Auswertung bei Hund und Katze

OpenAIRE

Weigel-Ossiander, Fiona Sarah

2016-01-01

Mit EKG Basics wurde ein detailliertes multimediales Lernprogramm über die Grundlagen der Elektrokardiographie bei Hund und Katze erstellt unter besonderer Berücksichtigung von didaktischen und ergonomischen Gesichtspunkten. Da vielen Veterinärmedizinerinnen/Veterinärmedizinern das Erlernen, Verstehen und Interpretieren der Elektrokardiographie schwer fällt, war das Ziel der vorliegenden Arbeit, sowohl Studierenden der Tiermedizin als auch interessierten Tierärztinnen/Tierärzten die Thema...

Calculation and Analysis of Differential Corrections for BeiDou

Science.gov (United States)

Yang, Sainan; Chen, Junping; Zhang, Yize

2015-04-01

BeiDou Satellite Navigation System has been providing service forAsia-Pacific area. BeiDou uses observations of regional monitoring network to determine satellite orbit, which limits the satellite orbit accuracy. And the satellite clock error is produced by time synchronization system. The time synchronization delay of antenna device is general obtained through prior Calibration, and the residual calibration error is included in the satellite clock, which affects the prediction accuracy of satellite clock error. In this paper, we study the algorithms of Beidou differential corrections to improve the accuracy of satellite signals to improve the user positioning accuracy. In this algorithm, both pseudo-range and phase observations are used to calculate differential corrections. We process pseudo-range observations to obtain equivalent satellite clock error, which include satellite clock errors and orbit radial errors, as well as the average projection of orbit tangential and normal errors in combination. And the epoch-difference of phase observations are processed to eliminate the ambiguity which simplifies algorithms and ensure the relative accuracy (corrections variety between the epochs). Observations more than 10 stations in China are processed, and the equivalent clock error calculation results are analyzed, which shows that the satellite UDRE are significantly reduced and user location accuracy improves when the equivalent clock error corrections are applied. The residuals deducting equivalent satellite clock error contains the projection difference of satellite orbit error in all station (tangential and normal errors are main). We utilize the residuals to solve the tangential and normal orbit errors which cause the projection difference. The same observation data is processed. The results show that after calculating three-dimensional corrections, the satellite UDRE doesn't improve significantly compared to equivalent satellite clock error corrections and user

Spontaneous aliquorrhea syndrome due to cervicothoracic liquor leak; Spontanes Liquorunterdrucksyndrom bei zervikothorakalem Liquorleck

Energy Technology Data Exchange (ETDEWEB)

Kuhl, V.; Thoemke, F.; Hopf, H.C. [Klinik und Poliklinik fuer Neurologie, Johannes-Gutenberg-Univ. Mainz (Germany); Andreas, J. [Klinik und Poliklinik fuer Nuklearmedizin, Johannes-Gutenberg-Univ. Mainz (Germany); Mueller-Forell, W. [Institut fuer Neuroradiologie, Johannes-Gutenberg-Univ. Mainz (Germany)

2000-07-01

The radiological and nuclear medicine methods applied for diagnostic evaluation in the case reported (MRI, myelography, liquor myeloscintigraphy) were the key modalities for diagnosis, explanation of causes, and follow-up and are described in this report. In case of recurrent headaches during therapy, a CCT examination should be performed in order to exclude the presence of subdural hematoma.(orig./CB) [German] Die radiologischen und nuklearmedizinischen Untersuchungsmethoden (MRT, Myelographie, Liquormyeloszintigraphie) nehmen zur Diagnosestellung, Ursachenabklaerung und Verlaufsbeurteilung eine zentrale Schluesselposition ein und wurden anhand unseres Fallbeispieles demonstriert und beschrieben. Bei Wiederauftreten von Kopfschmerzen im Verlauf der Erkrankung sollte zum Ausschluss subduraler Haematome eine CCT-Untersuchung erfolgen. (orig.)

Peripheral involvement of the joint in seronegative spondylarthritis; Periphere Gelenkbeteiligung bei seronegativen Spondarthritiden

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Lingg, G.; Soltesz, I. [Rheumazentrum Bad Kreuznach (Germany). Zentrales Roentgeninstitut

1997-10-01

The subjects of this contributions have been restricted to the peripheral manifestations of seronegative spondylarthrosis, for reasons of conciseness and clearness. The most frequent occurrences discussed are psoriasis arthritis and, a little bit less frequent, peripheral involvement of the joint in ancylosing spondylitis and Reiter syndrome, as well as enteropathic spondylarthrosis. (orig./AJ) [Deutsch] Als Thema dieser Veroeffentlichung wurden aus Gruenden der Kuerze und der Uebersichtlichkeit aber nur die peripheren Manifestationen der seronegativen Spondarthropathien gewaehlt. Hier wiederum haben wir es am haeufigsten mit der Psoriasisarthritis und etwas seltener mit der peripheren Gelenkbeteiligung bei der Bechterew`schen Erkrankung und der Reiter`schen Erkrankung sowie der enteropathischen Spondarthritiden zu tun. (orig./AJ)

Efficiencies of different flue gas purification systems in waste incinerators. Experimental report; Untersuchungen zur Effizienz von unterschiedlichen Systemen zur Rauchgasreinigung bei Muellverbrennungsanlagen. Untersuchungsbericht

Energy Technology Data Exchange (ETDEWEB)

Berghoff, R. (comp.)

2001-07-01

This investigation was carried out on behalf of the Environmental Office of the state of Nordrhein-Westfalen. Apart from the current and projected exhaust purification systems, also three exemplary systems were analyzed from the ecological and economic point of view. Effects on pollutant freights were established in consideration of energy consumption and the specific cost of waste treatment for each technology. [German] Das konkrete Ziel dieser vom Landesumweltamt NRW vergebenen Untersuchung war es, neben einer Uebersicht ueber die zzt. eingesetzten und auch geplanten Abgasreinigungssysteme (RGR) bei Muellverbrennungsanlagen, die Vor- und die Nachteile von 3 beispielhaft ausgewaehlten Systemen in einem oekologischen und oekonomischen Vergleich knapp und begrenzt darstellen zu lassen. Als Ergebnis wurden die Auswirkungen der unterschiedlichen Verfahren auf die Frachten der emittierten Schadstoffe unter Beruecksichtigung der unterschiedlichen Energieverbraeuche ermittelt und dargestellt. Darueber hinaus wurden die spezifischen Muellbehandlungskosten bei den jeweiligen Gasreinigungstechniken errechnet. (orig.)

Analysis of conservativity analysis for clearance levels. Final report; Konservativitaetsanalysen bei Freigabegrenzwerten. Schlussbericht

Energy Technology Data Exchange (ETDEWEB)

Deckert, A; Thierfeldt, S

1997-07-01

, raising the clearance levels would not lead to an increase of the material quantities because other nuclides of the respective nuclide vectors are limiting. In conclusion, the effort to alter the clearance levels of the 1995 SSK recommendation for conventional disposal does not seem worthwhile. (orig.) [Deutsch] Bei der Herleitung von Freigabewerten fuer Reststoffe/Abfaelle werden grundsaetzlich radiologisch notwendige Konservativitaeten einbezogen. Diese koennen fuer verschiedene Saetze von Freigabewerten allerdings stark differieren, was zu Inkompatibilitaeten zwischen Freigabepfaden fuehrt. Ziel ist daher der Vergleich der Konservativitaetsniveaus verschiedener Wertesaetze, wozu Konservativitaeten fuer Freigabewerte fuer Abfaelle zur Deponierung und fuer metallische Reststoffe analysiert werden. Es wurden Methoden erarbeitet, um den Grad an Konservativitaet quantitativ zu erfassen. Die Situation bei der Freigabe zur konventionellen Deponierung wurde analysiert, indem die aktuelle und zukuenftige Situation des Abfallaufkommens hinsichtlich Massen, Nuklidvektoren, geographischer Verteilung und Deponierung probabilistisch modelliert und die resultierende Dosisverteilung berechnet wurden. Als Freigabekriterium wurden die Grenzwerte fuer die Freigabe zur konventionellen Deponierung gemaess des SSK-Empfehlungsentwurfs von 1995 angesetzt. Auf der Basis realistischer Szenarien fuer die Exposition des Deponiepersonals und bei Zugrundelegung der Grenzwerte des SSK-Empfehlungsentwurfs wurde eine Dosisverteilung ermittelt, die zeigt, dass der Bereich des radiologischen Schutzziels im Bereich von 10 {mu}Sv/a nicht verlassen wird, auch wenn groessere Massen als 100 Mg/a freigegebenen Materials deponiert werden. Eine Beschraenkung der jaehrlich freigegebenen Masse oder Aktivitaet ist daher nicht erforderlich. Die Freigabewerte, die durch die Belastungspfade externe Bestrahlung und Inhalation bei Deponierpersonal bestimmt werden, weisen ein aehnliches Mass an Konservativitaet auf wie

Imaging diagnostics of breast metastases from extramammary tumors; Bildgebende Diagnostik bei Brustmetastasen extramammaerer Tumoren

Energy Technology Data Exchange (ETDEWEB)

Wienbeck, S.; Lotz, J. [Georg-August-Universitaet Goettingen, Institut fuer Diagnostische und Interventionelle Radiologie, Goettingen (Germany); Nemat, S. [Universitaet Homburg/Saar, Institut fuer Diagnostische und Interventionelle Radiologie, Homburg/Saar (Germany); Surov, A. [Universitaet Leipzig, Institut fuer Diagnostische und Interventionelle Radiologie, Leipzig (Germany)

2017-06-15

klinischen Merkmale und die unterschiedlichen Bildgebungsbefunde intramammaerer Metastasen solider extramammaerer Tumoren aufgezeigt. Brustmetastasen werden haeufig zufaellig in Zusammenhang mit einer Computertomographie (CT) oder Positronenemissionstomographie-Computertomographie (PET-CT) entdeckt. Mammographisch weisen Brustmetastasen 2 unterschiedliche bildgebende Erscheinungsmuster im Sinne von Herdbefunden oder aber einer Architekturstoerung mit Kutisverdickung auf. Diese kommen in der Regel als solitaere, seltener als multiple runde Herdbefunde mit glatter Randbegrenzung zur Darstellung. Assoziierter Mikrokalk tritt selten auf. Eine diffuse Architekturstoerung mit Kutisverdickung kommt gehaeuft bei Brustmetastasen der meisten Magenkarzinome, Ovarialkarzinome und Rhabdomyosarkome vor. Sonographisch stellen sich die Befunde hypoechogen, oval oder rund mit glatter Randbegrenzung und dorsaler Schallverstaerkung dar. Die MR-Kriterien bei Brustmetastasen sind dagegen inkonstant und koennen nicht sicher als benigne oder maligne klassifiziert werden. Die erhobenen radiologischen Befunde imponieren hierbei eher benigne, sodass bei bekannter Malignomerkrankung stets an das Vorliegen von Brustmetastasen gedacht werden sollte. (orig.)

Multicenter study of radiosynoviorthesis. Clinical outcome in osteoarthritis and other disorders with concomitant synovitis in comparison with rheumatoid arthritis; Multizenterstudie zur Radiosynoviorthese: Klinische Ergebnisse bei aktivierten Arthrosen und anderen Gelenkerkrankungen mit chronischer Synovialitis im Vergleich zur rheumatoiden Arthritis

Energy Technology Data Exchange (ETDEWEB)

Rau, H.; Lohmann, K.; Spitz, J. [Praxis fuer Nuklearmedizin, am Staedtischen Klinikum Wiesbaden (Germany); Franke, C. [Praxis fuer Nuklearmedizin, Hamburg (Germany); Goretzki, G. [Praxis fuer Nuklearmedizin, Bielefeld (Germany); Lemb, M.A. [Praxis fuer Nuklearmedizin, Bremen (Germany); Mueller, J. [Klinik fuer Nuklearmedizin, Kantonspital St. Gallen (Switzerland); Panholzer, P.J. [Abt. fuer Nuklearmedizin und Endokrinologie, PET-Zentrum, Krankenhaus der Barmherzigen Schwestern, Linz (Austria); Stelling, E. [Praxis fuer diagnostische und therapeutische Nuklearmedizin, Berlin (Germany)

2004-04-01

Aim: evaluation of the effectiveness of radiosynoviorthesis (RSO) in osteoarthritis and other disorders with concomitant synovitis versus rheumatoid arthritis by means of a standardized questionnaire. Patients, methods: 803 RSO treatments were monitored in 691 patients by standardized questionnaires of 7 centers in 3 countries. Patients were assigned to 3 groups according to their age (20-40, 41-60, 61-80 years). Additionally, the data were analyzed separately for patients with rheumatoid arthritis (group A) and those with osteoarthritis, psoriasis arthritis, pigmental villonodular synovitis or persistent effusions after joint replacement (group B). Results: ameliorations of joint pain, swelling/effusion or flexibility were found in 80% of group A and 56% of group B (p <0.01). Quality of life improved in 78% of group A and 59% of group B (p <0.01). The response rate was similar for small- and large-sized joints in group A, but significantly higher for large-sized joints in group B (p <0.01). The positive effects on joint pain, swelling/effusion or flexibility lasted longer in group A (p <0.01). Repeated RSOs were as effective as initial ones. The clinical outcome was neither influenced by age, nor gender, nor transient immobilisation for 48 hours after RSO. Conclusion: although slightly more efficient in rheumatoid arthritis, RSO represents an effective treatment option also in osteoarthritis and other disorders with concomitant synovitis. (orig.) [German] Ziel: Effektivitaetsvergleich der Radiosynoviorthese (RSO) bei aktivierter Arthrose und anderen Gelenkerkrankungen mit chronischer Synovialitis versus rheumatoider Arthritis. Ueberpruefung der Eignung eines standardisierten Fragebogens fuer Multizenterstudien. Patienten, Methoden: Bei 691 Patienten wurden 803 RSO-Behandlungsverlaeufe von 7 Zentren in 3 Laendern mit Hilfe eines standardisierten Fragebogens erfasst. Die Patienten wurden 3 Alterskategorien (20-40, 41-60 und 61-80 Jahre) zugeordnet. Ausserdem wurden

{sup 1}H-MR spectroscopy in anorexia nervosa. Reversible cerebral metabolic changes; {sup 1}H-MR-Spektroskopie bei Anorexia nervosa: Reversible zerebrale Metabolitenaenderungen

Energy Technology Data Exchange (ETDEWEB)

Moeckel, R.; Schlemmer, H.P.; Becker, G.; Koepke, J.; Georgi, M. [Heidelberg Univ. (Germany). Inst. fuer Klinische Radiologie; Gueckel, C.; Goepel, C.; Schmidt, M. [Zentralinstitut fuer Seelische Gesundheit, Mannheim (Germany). Klinik fuer Kinder- und Jugendpsychiatrie; Hentschel, F. [Zentralinstitut fuer Seelische Gesundheit, Mannheim (Germany). Neuroradiologie

1999-04-01

Purpose: By using localized {sup 1}H-MR spectroscopy in the brain of patients with anorexia nervosa we wanted to verify our preliminary results and to look for a reversibility of the metabolic changes under therapy. Methods: In 22 patients and 17 healthy volunteers (11 follow-up examinations) single voxel {sup 1}H-MR spectroscopy (TE=50 ms, TM=30 ms, TR=1500 ms, voxel (2 cm){sup 3}, acq.: 256) was used in two different localizations (thalamus and parieto-occipital region). The first examination of the patients was performed before therapy, the follow-up examination at the end of therapy. Results: In both regions of the brain we found a statistically significant elevation of the Cho/Cr-ratio in comparison to normal controls. The follow-up examinations revealed reversibility of the metabolic changes under successful therapy. Conclusion: {sup 1}H-MR spectroscopy reveals metabolic changes in the brain of patients with anorexia nervosa, which are reversible under successful therapy. These metabolic changes can be conclusively explained using a biochemical model. (orig.) [Deutsch] Ziel: Im Rahmen dieser weiterfuehrenden Studie sollten die bisherigen Ergebnisse der lokalisierten {sup 1}H-MR-Spektroskopie des Gehirns an Patienten mit Anorexia nervosa verifiziert werden. Weiter sollte ueberprueft werden, ob die von uns nachgewiesenen metabolischen Veraenderungen unter Therapie reversibel sind. Methode: Die {sup 1}H-MR-Spektren wurden bei 22 Patientinnen und 17 Probanden (11 Verlaufskontrollen) in Einzelvolumentechnik (TE=50 ms, TM=30 ms, TR=1500 ms, Voxel: (2 cm){sup 3}, Acq.: 256) in zwei unterschiedlichen Hirnregionen (Thalamus, parieto-okzipitale Region) durchgefuehrt. Die erste Untersuchung der Patienten erfolgte bei Aufnahme und die Verlaufskontrolle zum Abschluss der stationaeren Behandlung. Ergebnisse: Bei den Patienten wurde in beiden Hirnregionen ein statistisch signifikant erhoehter Wert fuer das Cho/Cr-Verhaeltnis im Vergleich zu dem Normalkollektiv nachgewiesen

Einfluss der Lage des aktiven Kontaktes innerhalb des Nucleus subthalamicus auf den Effekt der tiefen Hirnstimulation bei Parkinson Patienten- Eine MRT-basierte Untersuchung

OpenAIRE

Wodarg, Fritz

2013-01-01

Anhand Prä- und postoperativer MRT-Bilder wird die Lage der Elektroden zur Hochfrequenzstimulation innerhalb des N. subthalamicus bestimmt und mit dem klinischen Ergebnis der Stimulation bei 30 Parkinson Patienten korreliert. Eine Stimulation in lateralen Anteilen des STN bringt signifikant bessere klinische Ergebnisse.

Dissection or irradiation of the axilla in postmenopausal patients with breast cancer? Long-term results and late effects in 655 patients; Axilladissektion oder Axillabestrahlung bei postmenopausalen Patientinnen mit Mammakarzinom?

Energy Technology Data Exchange (ETDEWEB)

Albrecht, M.R.; Zink, K.; Ruehl, U. [Abt. fuer Strahlentherapie, Klinikum im Friedrichshain, Standort Moabit, Berlin (Germany); Busch, W. [Abt. fuer Gynaekologie, Krankenhaus Moabit Berlin (Germany)

2002-09-01

Patients and methods: From 1986 to 1993 we irradiated 655 patients with breast cancer after breast conserving surgery (BET). In all 144 cN1- and all 209 premenopausal cNO-patients axillary dissection was recommended. Of 302 postmenopausal cNO-patients 129 had breast surgery in our institution. In a total of 129 patients axillary dissection was replaced by irradiation (AxRT-group). They were compared with all 173 patients referred from other hospitals for irradiation after both breast conserving surgery and axillary dissection (AxOP-group). Dissected patients with gross tumor involvement of the axilla or less than eight nodes removed had additional axillary irradiation. Patients age, tumor size, vessel-, muscle- or skin invasion and grading were similar in both groups. However, in the AxRT-group there were more patients with negative hormon receptors, multifocal and medial sited tumors. Late complications after dissection and/or irradiation of the axilla were evaluated in 502 patients free of locoregional relapse and with a minimal follow up of 3 years (media 9,5 years). Results: After 5, 10 and 15 years tumor free survival rated were 90%, 82% and 79% in the AxOP-group vs 91%, 82% and 80% in the AxRT-group, respectively (p = 0.95). Overall survival (p = 0.98) local (p = 0.47) and axillary control (p = 0.12) were equal in both groups. However, serious problems like lymphedema of the arm, pain, mobility impairment occured in 26% patients following axillary dissection but only in 1% after axillary irradiation. No difference in late sequelae after axillary dissection with or without irradiation could be detected (26 vs 27%). (orig.) [German] Patientinnen und Methoden: Von 1986 bis 1993 wurden 655 Patientinnen mit Mammakarzinom nach brusterhaltender Operation (BET) bestrahlt. Davon waren praeoperativ 144 cN1- und 511 cNO-Patientinnen. Bei allen 144 cN1- und allen 209 praemenopausalen cNO-Patientinnen war eine Axilladissektion vorgesehen. Von 302 postmenopausalen c

MR-Guided vacuum biopsy of 206 contrast-enhancing breast lesions; MRT-gefuehrte Vakuumbiopsie bei 206 Kontrastmittel anreichernden Laesionen der Mamma

Energy Technology Data Exchange (ETDEWEB)

Perlet, C.; Schneider, P.; Sittek, H.; Reiser, M.F. [Klinikum der Universitaet Grosshadern, Muenchen (Germany). Inst. fuer Klinische Radiologie; Amaya, B.; Grosse, A.; Heywang-Koebrunner, S.H. [Martin-Luther-Universitaet, Halle (Germany). Klinik fuer Diagnostische Radiologie

2002-01-01

Purpose: To determine the accuracy and clinical use of MR-guided vacuum biopsy (VB) of enhancing breast lesions. Material and Methods: 254 lesions were referred to MR-guided vacuum-assisted breast biopsy. In 43 (16%) patients the indication was dropped because the lesions could not be identified at the time VB was scheduled. This was due to hormonal influences (n=37), to too strong compression (n=3) or to misinterpretation of the initial diagnostic MRI. In 5 cases (2%) VB was not performed due to obesity (n=2); problems of access (n=2) or a defect of the MR-unit (n=1). VB was performed on altogether 206 lesions. In 4 cases (2%) VB was unsuccessful. This was immediately realized on the post-interventional images. Thus a false negative diagnosis was avoided. Verification included excision of the cavity in cases with proven malignancy or atypical ductal hyperplasia (ADH) and (for benign lesions) retrospective correlation of VB-histology with pre- and postinterventional MRI and subsequent follow-up. Results: 51/202 successful biopsies proved malignancy. In 7 cases ADH and in 144 cases a benign lesion was diagnosed. One DCIS was underestimated as ADH. All other benign or malignant diagnoses proved to be correct. Conclusion: MR-guided VB allows reliable histological work-up of contrast-enhancing small lesions which are not visible by any other modality. (orig.) [German] Zielsetzung: Evaluation der Wertigkeit und klinischen Anwendbarkeit der MRT-gefuehrten Vakuumbiopsie (VB) bei anreichernden Mammalaesionen. Material und Methoden: Insgesamt wurden 254 Laesionen der MRT-gefuehrten VB zugewiesen. Hiervon entfiel bei 43 Patientinnen (16%) die Biopsieindikation beim Planungs-MRT, da die urspruengliche Anreicherung hormonell (n=37), durch zu starke Kompression (n=3) oder durch eine Fehlinterpretation des vorausgegangenen diagnostischen MRT (n=3) nicht mehr abgrenzbar war. Bei 5 weiteren Laesionen (2%) war die Biopsie nicht moeglich (Adipositas n=2; Zugangsprobleme n=2; MRT

PENGARUH AUDIT TENURE, UKURAN AUDITOR, SPESIALISASI AUDIT DAN AUDIT CAPACITY STRESS TERHADAP MANAJEMEN LABA (Studi Empiris pada Perusahaan Manufaktur yang listed di BEI tahun 2010-2015

Directory of Open Access Journals (Sweden)

Deddy Kurniawansyah

2016-11-01

Full Text Available The purpose for this research is to test audit tenure, auditor size, audit specialization industry, and audit capacity stress to earning management manufacture industry listed in the BEI in 2010-2015. In this research, we use leverage, firms size, and ROA as Control variable. This study population was manufacture industry listed in the BEI in 2010-2015. This population use criteria population by 703 annual reports manufacture industy. The sampling used in this study a sensus method. Source of data is secondary data, obtained from annual reports of manufacture industry in BEI. This study used multiple regretion analysis to analysis data with the help of the program Partial Last Square (PLS. The results obtained in this study is audit tenure, and audit capacity stress has a positive effect on earning management manufacture industry. Auditor size, and audit specialization industry has a negative effect on earning management manufacture industry. For control variable, the results obtained is leverage, firms size, and ROA has a positive effect on earning management manufacture industry. The results provide more informed basis for investors to be more selective in investing their funds. To reduce earnings management practices in companies should principals switched auditors periodically or less than 3 years, and using scale big four auditors, and has specialized audit industry.

A HARMONIZAÇÃO DOS PADRÕES CONTÁBEIS INTERNACIONAIS NO CONTEXTO DA GLOBALIZAÇAO E SUA EVOLUÇAO NO BRASIL

Directory of Open Access Journals (Sweden)

Danival Sousa Cavalcante

2012-06-01

Full Text Available O fenômeno da globalização, em grande medida, implica a homogeneização de estratégias e práticas, em busca de maior eficiência e/ou legitimidade. No contexto atual, diversos tipos de organizações inserem-se no mercado global. Todas assumem, assim, a obrigação de prestar contas acerca de suas operações e resultados, para um amplo conjunto de stakeholders. Neste cenário, a contabilidade assume papel informacional estratégico, através de técnicas que retratem a posição econômica e a financeira das organizações para os diversos usuários. Verifica-se, porém, um paradoxo, pois, apesar da necessidade de os relatórios contábeis serem cada vez mais globalizados, cada país tem práticas contábeis próprias. O estudo tem como objetivo analisar a relação entre a globalização e o processo de harmonização contábil internacional. A metodologia alinha-se ao modelo de compilação, quando se busca compulsar criticamente parte significativa da literatura pertinente disponível e expô-la de forma clara. Conclui-se que a globalização atua como mecanismo de isomorfismo. O início do processo de harmonização contábil se deu sob o choque da globalização, no início da década de 1990. Como sistema normativo, a governança corporativa constitui, também, um mecanismo de isomorfismo, contribuindo para a convergência das normas contábeis.

AS ESTRATÉGIAS UTILIZADAS NO PROCESSO DE ENSINO-APRENDIZAGEM: CONCEPÇÕES DE ALUNOS E PROFESSORES DE CIÊNCIAS CONTÁBEIS

Directory of Open Access Journals (Sweden)

Sady Mazzioni

2013-06-01

Full Text Available As diretrizes curriculares nacionais propõem ao curso de Ciências Contábeis uma formação que contemple os aspectos específicos da atuação do futuro profissional, mas recomenda também a inclusão de discussões que permitam a consciência cidadã e o enfrentamento dos problemas sociais. A construção das habilidades e competências designadas no perfil do egresso desejado se dá, em certa medida, no uso de estratégias de ensino-aprendizagem condizentes. O uso de formas e procedimentos de ensino deve considerar que o modo pelo qual o aluno aprende não é um ato isolado, escolhido ao acaso, sem análise dos conteúdos trabalhados, sem considerar as habilidades necessárias para a execução e dos objetivos a serem alcançados. O objetivo central da pesquisa é compreender as estratégias de ensino-aprendizagem mais significativas a partir das perspectivas dos alunos com aquelas utilizadas pelos professores do curso de graduação em Ciências Contábeis. Os procedimentos metodológicos utilizados caracterizam o estudo quanto aos objetivos como pesquisa descritiva; quanto aos procedimentos, pesquisa de levantamento; quanto à abordagem do problema, a pesquisa apresenta aspectos de natureza qualitativa e quantitativa. A coleta de dados foi realizada com o uso de questionários com perguntas abertas e fechadas, direcionadas a docentes e discentes do curso de graduação em Ciências Contábeis. Os resultados apontam para uma convergência de estratégias preferidas pelos universitários pesquisados com aquelas utilizadas pelos docentes.

[Cardiodoron® bei Patienten mit Schlafstörungen - Ergebnisse einer prospektiven Beobachtungsstudie].

Science.gov (United States)

Rother, Claudia; Schnelle, Martin

Hintergrund: Schlafstörungen gehören zu den häufigsten gesundheitlichen Problemen der heutigen Zeit. Stress und die dadurch bedingte innere Anspannung sowie eine unrhythmische Lebensführung z.B. durch Schichtarbeit sind bekannte auslösende Faktoren. Weniger bekannt ist, dass auch funktionelle Herz-Kreislauf-Beschwerden zu Störungen des Schlafs führen können und dass deren Behandlung zu einer Verbesserung der Schlafqualität beiträgt. Ganzheitlich betrachtet geht es daher um die Wiederherstellung einer gesunden Rhythmik, insbesondere des Herz-/Atem- sowie des Schlaf-Wach-Rhythmus, die Cardiodoron®, eine Heilpflanzenkomposition aus Primula veris, Hyoscyamus niger und Onopordum acanthium, unterstützt. Patienten und Methoden: Mittels einer prospektiven, multizentrischen Beobachtungsstudie sollte ermittelt werden, wie sich funktionelle Herz-Kreislauf-Beschwerden und/oder Schlafstörungen unter der Behandlung mit Cardiodoron® (Dilution) über 3-6 Monate entwickeln. Im Zeitraum von September 2009 bis März 2012 dokumentierten 92 Ärzte 501 Patienten, von denen 380 über Schlafstörungen klagten und deren Daten in dieser Publikation näher betrachtet werden. Nach einer Aufnahmeuntersuchung erfolgte nach 90 Tagen eine Abschlussuntersuchung und bei Fortführung der Therapie nach nochmals 90 Tagen eine Follow-up-Untersuchung. Neben 30 ärztlicherseits bewerteten Symptomen beurteilten die Patienten ihr Befinden mittels Pittsburgh Sleep Quality Index (PSQI) nach Buysse und der Beschwerden-Liste nach von Zerssen (B-L und B-L'). Ergebnisse: Unter der Cardiodoron®-Therapie gingen bei guter Verträglichkeit sowohl die Ausprägung der Schlafstörungen (um 65% von 2,0 auf 0,7 Punkte) als auch die erfassten 30 Symptome (um 59% von 24,3 auf 9,9 Punkte) deutlich zurück (p mit Schlafstörungen (mit oder ohne funktionelle Herz-Kreislauf-Beschwerden) kann die Ausprägung der Beschwerden mit Cardiodoron® deutlich gesenkt werden. Cardiodoron® ist gut verträglich. © 2016 S

Evaluation eines Intensivtherapie-Programms zur Behandlung schwerer Verhaltensstörungen bei geistig Behinderten mit autistischen oder psychotischen Verhaltensweisen

OpenAIRE

Elbing, Ulrich; Rohmann, Ulrich H.

1993-01-01

Die vorliegende Studie dokumentiert den Verlauf schwerer Verhaltensstörungen und erwünschten Zielverhaltens bei Geistigbehinderten mit z. T. autistischen oder psychotischen Verhaltensweisen, die vor, während und nach der Durchführung eines Intensivtherapie Programms in einem Heim fur Geistig- und Mehrfachbehinderte beobachtet wurden. Der Artikel faßt sieben Einzelfallstudien zusammen, die als Längsschnitt-Beobachtungen das Verhalten zwischen 18 und 33 Wochen überwiegend in multiple baseline d...

Naturwissenschaftliche Bildung fördern Indikatoren und Zusammenhänge bei Entwicklungsprozessen in SWiSE

CERN Document Server

Felchlin, Irene; Labudde, Peter

2016-01-01

PISA und TIMSS führten zu einem vermehrten Kompetenzdiskurs in Schule, Unterricht und Bildungspolitik. SWiSE versucht kompetenzorientierten Unterricht durch die Einführung bzw. Weiterentwicklung des selbstständigen Lernens, offener Lehr-Lernformen und Lehrerkooperation zu fördern. Doch stellt sich die Frage, wie unterrichtsrelevant solche Entwicklungsversuche sind. Die Buchbeiträge widmen sich der praxistauglichen Förderung von naturwissenschaftlichem Unterricht. Sie zeigen die Bedeutung von Schule als integrierendem System für alle Beteiligten bei Entwicklungsprozessen. Anhand empirischer Daten aus der Projektevaluation ergeben sich Ansätze zur Umsetzung auf den Ebenen Schule, Lehrpersonen und Lernende.

An Improved BeiDou-2 Satellite-Induced Code Bias Estimation Method

Directory of Open Access Journals (Sweden)

Jingyang Fu

2018-04-01

Full Text Available Different from GPS, GLONASS, GALILEO and BeiDou-3, it is confirmed that the code multipath bias (CMB, which originate from the satellite end and can be over 1 m, are commonly found in the code observations of BeiDou-2 (BDS IGSO and MEO satellites. In order to mitigate their adverse effects on absolute precise applications which use the code measurements, we propose in this paper an improved correction model to estimate the CMB. Different from the traditional model which considering the correction values are orbit-type dependent (estimating two sets of values for IGSO and MEO, respectively and modeling the CMB as a piecewise linear function with a elevation node separation of 10°, we estimate the corrections for each BDS IGSO + MEO satellite on one hand, and a denser elevation node separation of 5° is used to model the CMB variations on the other hand. Currently, the institutions such as IGS-MGEX operate over 120 stations which providing the daily BDS observations. These large amounts of data provide adequate support to refine the CMB estimation satellite by satellite in our improved model. One month BDS observations from MGEX are used for assessing the performance of the improved CMB model by means of precise point positioning (PPP. Experimental results show that for the satellites on the same orbit type, obvious differences can be found in the CMB at the same node and frequency. Results show that the new correction model can improve the wide-lane (WL ambiguity usage rate for WL fractional cycle bias estimation, shorten the WL and narrow-lane (NL time to first fix (TTFF in PPP ambiguity resolution (AR as well as improve the PPP positioning accuracy. With our improved correction model, the usage of WL ambiguity is increased from 94.1% to 96.0%, the WL and NL TTFF of PPP AR is shorten from 10.6 to 9.3 min, 67.9 to 63.3 min, respectively, compared with the traditional correction model. In addition, both the traditional and improved CMB model have

MRI of aseptic osteonecrosis in children with acute lymphoblastic leukemia; Kernspintomographie von aseptischen Osteonekrosen bei Kindern und Jugendlichen mit einer akuten lymphoblastischen Leukaemie

Energy Technology Data Exchange (ETDEWEB)

Engelbrecht, V.; Scherer, A.; Moedder, U. [Duesseldorf Univ. (Germany). Inst. fuer Diagnostische Radiologie; Bruder, M. [Duesseldorf Univ. (Germany). Kinderklinik; Koerholz, D. [Leipzig Univ. (Germany). Kinderonkologie

2000-04-01

Purpose: To evaluate the incidence, localisation, and course of symptomatic aseptic osteonecrosis (AON) in children undergoing treatment for acute lymphoblastic leukemia (ALL). Methods: 72 MRI examinations obtained from 26 children with bone pain selected from a group of 121 children with ALL were evaluated retrospectively. The area of the AON was determined by computer assisted planimetry. Follow-up examinations after 2-5 years were considered. Results: 10/121 (8.3%) of the children had symptomatic AON, the number of lesions varied between 1 and 24 per child. 62/66 lesions were localized within the lower extremities. 58% of the AON were positioned in the epiphysis and 42% in the meta- and diaphysis. The mean area of AON was 7.6 cm{sup 2} with a range of 0.5 to 50 cm{sup 2}. Follow-up examinations revealed a regression in 19 AON, no change in 43 and a progression in 4 lesions. AON within the epiphysis with joint involvement or lesions greater than 9 cm{sup 2} more frequently showed a progression of AON with final joint destruction. An elevated risk for AON was seen in children older than 10 years and in children with intensified chemotherapy due to high-risk ALL. Conclusion: AON is a common complication in ALL-children under chemotherapy. Most frequently, the course is benign but large AON with joint involvement have an elevated risk for progression of AON with final joint destruction. (orig.) [German] Ziel: Erfassung von Haeufigkeit, Lokalisation und Verlauf von symptomatischen aseptischen Osteonekrosen (AON) bei Kindern und Jugendlichen unter der Therapie einer akuten lymphoblastischen Leukaemie (ALL). Methoden: In einer Gruppe von 121 Kindern mit ALL (Alter 1-17 Jahre) wurden retrospektiv 72 MRT der Extremitaeten bei 26 Kindern mit Knochenschmerzen bezueglich der Zahl, Groesse und Lokalisation von AON ausgewertet. Die Flaeche von AON wurde planimetrisch bestimmt. Verlaufskontrollen erstreckten sich ueber 2-5 Jahre. Ergebnisse: 10/121 (8,3%) der Kinder wiesen

AS INFORMAÇÕES CONTÁBEIS E O AMBIENTE ECONÔMICO

Directory of Open Access Journals (Sweden)

Amaro Luiz de Oliveira Gomes

2009-09-01

Full Text Available As demonstrações financeiras, balanços patrimoniais, demonstrações do resultado, demonstrações de fluxo de caixa, acompanhadas das respectivas notas explicativas são a principal fonte de informações sobre as atividades econômicas relacionadas a uma determinada empresa. Tais fontes são utilizadas freqüentemente para avaliar o desempenho de uma instituição e de seus administradores, bem como para inferir sobre as perspectivas futuras do negocio. Embora sirva a uma variedade de usuários e para uma serie de utilidades, reconhece-se que as informações contábeis são basicamente utilizadas por aqueles que estão fora da empresa, tais como fornecedores, financiadores, os investidores, os quais estão preocupados principalmente com o destino dado pela gerencia da empresa aos recursos investidos.

A FORMAÇÃO COMPORTAMENTAL DE AUDITORES CONTÁBEIS INDEPENDENTES: UM ESTUDO MULTICASO [doi: 10.5329/RECADM.20020102004

Directory of Open Access Journals (Sweden)

Luiz Alberton

2002-11-01

Full Text Available RESUMO O presente artigo tem como objetivo apresentar uma proposta de um modelo de formação comportamental para auditores contábeis independentes. Deste modo, inicialmente, discorre-se sobre os aspectos que devem ser considerados pelo profissional responsável pela gestão das pessoas nas organizações que prestam serviços de auditoria contábil independente, e do perfil destas pessoas requerido pelas empresas. Em seguida são identificadas as teorias que tratam da gestão de pessoas nas organizações, especificamente nos processos de recrutamento e seleção, capacitação e avaliação de desempenho. As empresas buscam profissionais com talentos e, principalmente, que saibam manter o equilíbrio entre a razão e a emoção no ambiente de trabalho. Na literatura que versa sobre a profissão do auditor contábil, é dada muita ênfase aos aspectos técnicos, tratando superficialmente ou renegando os aspectos comportamentais considerados importantes ao desempenho destes profissionais. Para confirmar essas afirmações e dar suporte ao delineamento do modelo, é realizada uma pesquisa de campo com os responsáveis pela gestão de pessoas em quatro empresas internacionais de auditoria contábil independente, que fazem parte das big five, e em uma empresa nacional. Assim, para o delineamento do modelo de formação, a ênfase desta pesquisa recai sobre os aspectos de liderança, comunicação, motivação, negociação, coaching, mentoring, administração de conflitos, trabalho em equipe, técnica de entrevista, análise transacional e de programação neurolingüística, que podem ser utilizados para o desenvolvimento de auditores contábeis independentes, de forma que possam melhorar suas condições de competitividade e empregabilidade. Portanto, são incorporados esses conceitos como ponto de partida para o delineamento de um modelo de formação comportamental de auditores contábeis independentes.

Functional imaging of neurocognitive dysfunction in attention deficit hyperactivity disorder; Bildgebende Darstellung neurokognitiver Dysfunktionen bei der Aufmerksamkeitsdefizit-/Hyperaktivitaetsstoerung

Energy Technology Data Exchange (ETDEWEB)

Wolf, I [Klinik fuer Psychiatrie und Psychotherapie des Kindes- und Jugendalters der Universitaet Heidelberg, Zentralinstitut fuer Seelische Gesundheit, Mannheim (Germany); NMR-Forschung der Universitaet Heidelberg (Germany). Klinik fuer Psychiatrie und Psychotherapie; Klinik fuer Psychiatrie und Psychotherapie des Kindes- und Jugendalters, Zentralinstitut fuer Seelische Gesundheit, Mannheim (Germany); Tost, H; Ruf, M; Ende, G [NMR-Forschung der Universitaet Heidelberg (Germany). Klinik fuer Psychiatrie und Psychotherapie; Schmidt, M H [Klinik fuer Psychiatrie und Psychotherapie des Kindes- und Jugendalters der Universitaet Heidelberg, Zentralinstitut fuer Seelische Gesundheit, Mannheim (Germany)

2005-02-01

vorwiegend vererbte neurobiologisch begruendete Erkrankung hinweisen. Die Entwicklung nichtinvasiver bildgebender Verfahren in den letzten 15 Jahren hat die paediatrische Forschung auf diesem Gebiet entscheidend bereichert. Funktionell bildgebende Studien konnten deutliche Hinweise auf die neurobiologischen Korrelate gestoerter Exekutivfunktionen, mangelhafter Impulskontrolle und auffaelliger Psychomotorik erbringen. Die hierbei gefundenen Dysfunktionen frontostriataler Regelkreise stehen in Einklang mit den frueher beschriebenen Volumenminderungen frontaler Hirnstrukturen und pathologischer Veraenderungen der Basalganglien und des Cerebellums. Insbesondere die Steuerung visueller Aufmerksamkeit ist von Stoerungen dieser beschriebenen Hirnregionen beeintraechtigt. Aktuelle Untersuchungen konnten zeigen, dass bei ADHS-Kranken ebenfalls haeufig eine mangelhafte Kontrolle visuomotorischer Faehigkeiten vorliegt. Die vorliegende Arbeit gibt einen Ueberblick zum aktuellen Forschungsstand funktioneller Bildgebung bei ADHS und geht dabei speziell auf okulomotorische Dysfunktionen und deren Erfassung bei kernspintomographischen Untersuchungen ein. (orig.)

Multivariate analysis of factors influencing the effect of radiosynovectomy; Multivariate Analyse der Einflussfaktoren auf die Wirkung der Radiosynoviorthese bei entzuendlichen Gelenkerkrankungen

Energy Technology Data Exchange (ETDEWEB)

Farahati, J.; Schulz, G.; Koerber, C.; Geling, M.; Schmeider, P.; Reiners, Chr. [Wuerzburg Univ. (Germany). Klinik fuer Nuklearmedizin; Wendler, J. [Erlangen-Nuernberg Univ. (Germany). Klinik fuer Innere Medizin III; Kenn, W. [Wuerzburg Univ. (Germany). Inst. fuer Roentgendiagnostik; Reidemeister, C. [Wuerzburg Univ. (Germany). Klinik fuer Innere Medizin

2002-04-01

Objective: In this prospective study, the time to remission after radiosynovectomy (RSV) was analyzed and the influence of age, sex, underlying disease, type of joint, and duration of illness on the success rate of RSV was determined. Methods: A total number of 57 patients with rheumatoid arthritis (n = 33) and arthrosis (n = 21) with a total number of 130 treated joints (36 knee, 66 small and 28 medium-size joints) were monitored using visual analogue scales (VAS) from one week before RSV up to four to six months after RSV. The patients had to answer 3 times daily for pain intensity of the treated joint. The time until remission was determined according to the Kaplan-Meier survivorship function. The influence of the prognosis parameters on outcome of RSV was determined by multivariate discriminant analysis. Results: After six months, the probability of pain relief of more than 20% amounted to 78% and was significantly dependent on the age of the patient (p = 0.02) and the duration of illness (p = 0.05), however not on sex (p = 0.17), underlying disease (p = 0.23), and type of joint (p = 0.69). Conclusion: Irrespective of sex, type of joint and underlying disease, a measurable pain relief can be achieved with RSV in 78% of the patients with synovitis, whereby effectiveness is decreasing with increasing age and progress of illness. (orig.) [German] Ziel: In dieser prospektiven Studie wurde die Zeit bis zur Remission nach einer Radiosynoviorthese (RSO) untersucht. Ebenso wurde der Einfluss von Alter, Geschlecht, Grunderkrankung, Gelenktyp und Erkrankungsdauer auf die Erfolgsrate der RSO ermittelt. Methodik: Bei insgesamt 57 Patienten mit rheumatoider Arthritis (n = 33) und Arthritis bei aktivierter Arthrose (n = 24) wurden 130 Gelenke (36 Kniegelenke, 66 kleine und 28 mittelgrosse Gelenke) behandelt. Die Patienten wurden unter Verwendung so genannter visueller Analogskalen eine Woche vor RSO und vier bis sechs Monate danach 3-mal taeglich zur Schmerzintensitaet des

Retrospective results of radiation therapy of the Eustachian tube in chronic otitis media; Retrospektive Ergebnisse der perkutanen Strahlentherapie der Tuba Eustachii bei chronischer Otitis media

Energy Technology Data Exchange (ETDEWEB)

Schultze, J.; Reinke, C.; Kimmig, B. [Klinik fuer Strahlentherapie (Radioonkologie), Universitaetsklinikum Kiel (Germany); Frese, K.A. [Klinik fuer Hals-, Nasen- und Ohrenheilkunde, Kopf- und Halschirurgie, Universitaetsklinikum Kiel (Germany)

2003-01-01

Background: The treatment results of symptomatic radiation therapy of the Eustachian tube in chronic otitis media had to be evaluated retrospectively. Patients and Methods: Between 1980 and 1997, 66 patients were referred for therapy. The median age was 58 years. In the clinical presentation, all the patients had a hearing impairment, 35 patients complained of pain, 21 had otorrhea. In their history, 20 patients indicated chronic recurrent infections. The complaints lasted for 4.7 years in the median, primary conservative (adstringentia, antibiotics) and surgical treatment (paracentesis, tympanic tubule, tympanoplastic) did not lead to lasting cure. In 40 of 66 patients, finally radiation therapy was done of both Eustachian tubes. With opposed fields and cobalt-60 photons a total dose of 6 Gy at single doses of 1 Gy, three times a week, was applied. Under the causes for exclusion of radiation therapy were non-acceptance of the patients (nine), prior radiation therapies (six) or spontaneous improvement after initial presentation in our department. The treatment results were evaluated by interviews of the patients and regular otorhinolaryngological examinations. Results: There were no side effects noticed. 28 of 40 (70%) patients reported a significant improvement that could be verified by objective otorhinolaryngological examinations. In the group of 26 nonirradiated patients, 22 could be interviewed indicating in 16 cases (72%) that the complaints were unchanged and chronic otitis media was lasting. In a subgroup analysis concerning the duration of otitis media radiation therapy proved more effective in an acute and subacute stadium of disease of up to 5 years duration, while the patients resistant to radiation therapy were entirely in a chronic stage of disease exceeding 5 years duration. (orig.) [German] Hintergrund: Die Behandlungsergebnisse der symptomatischen Radiotherapie bei chronischer Otitis media sollten retrospektiv evaluiert werden. Patienten und

Analysis on coverage ability of BeiDou navigation satellite system for manned spacecraft

Science.gov (United States)

Zhao, Sihao; Yao, Zheng; Zhuang, Xuebin; Lu, Mingquan

2014-12-01

To investigate the service ability of the BeiDou Navigation Satellite System (BDS) for manned spacecraft, both the current regional and the future-planned global constellations of BDS are introduced and simulated. The orbital parameters of the International Space Station and China's Tiangong-1 spacelab are used to create the simulation scenario and evaluate the performance of the BDS constellations. The number of visible satellites and the position dilution (PDOP) of precision at the spacecraft-based receiver are evaluated. Simulation and analysis show quantitative results on the coverage ability and time percentages of both the current BDS regional and future global constellations for manned-space orbits which can be a guideline to the applications and mission design of BDS receivers on manned spacecraft.

Monitoring of organic loads at waste water treatment plant with due consideration of factual necessity, technical feasibility and statutory requirements; Erfassung der organischen Belastung bei Abwasserreinigungsanlagen unter Beachtung der fachlichen Notwendigkeit, der technischen Moeglichkeiten und der gesetzlichen Auflagen

Energy Technology Data Exchange (ETDEWEB)

Baumann, P. [Stuttgart Univ. (Germany). Inst. fuer Siedlungswasserbau, Wasserguete- und Abfallwirtschaft

1999-07-01

Between the statutory requirement and factual necessity for monitoring organic loads in waste water discharged to municipal and industrial waste water treatment plant and effluents from these there are substantial discrepancies. The paper points out the different approaches and gives recommendations on how to proceed in the future. At plant with stable nitrification, self and external monitoring for BOD{sub 5} can be distinctly reduced without fear of impaired process transparency or water quality. Monitoring organic loads online is little expedient technically, especially where effluent from municipal sewage treatment plants is concerned. But in the industrial sector there exist the most diverse applications with a view to carbon elimination. (orig.) [German] Zwischen den gesetzlichen Anforderungen und der fachlichen Notwendigkeit bei der Erfassung der organischen Belastung im Zu- und Ablauf von kommunalen und industriellen Klaeranlagen bestehen erhebliche Diskrepanzen. In diesem Beitrag werden die unterschiedlichen Ansaetze aufgezeigt und Empfehlungen fuer die zukuenftige Vorgehensweise gegeben. Bei Anlagen mit stabiler Nitrifikation ist die Selbst- wie Fremdueberwachung bezueglich BSB{sub 5} deutlich zu reduzieren, ohne dass Einbussen fuer Prozesstransparenz und Gewaesserqualitaet zu erwarten sind. Die online-Ueberwachung der organischen Belastung ist insbesondere bei Ablaeufen in kommunalen Klaeranlagen fachlich wenig sinnvoll, im Bereich der industriellen Abwasserreinigung ergeben sich dafuer bei dem Reinigungsziel der Kohlenstoffelimination dagegen verschiedenste Anwendungsmoeglichkeiten. (orig.)

Transvenous DSA: ECG-controlled cardial effects and venous complications after pre-atrial injection of nonionic contrast media

International Nuclear Information System (INIS)

Arlart, I.P.; Sigel, H.

1986-01-01

Transvenous DSA is a diagnostic technique for ambulatory examination that is well tolerated by patients, although it is commonly known that bolus injection of contrast medium for examination of the cardiovascular system may affect the cardiovascular hemodynamic process. The prospective study described was intended to reveal in 100 patients the effects on ECG data, as well as clinical symptoms of non-tolerance of contrast medium (nonionic, with high iodine content, Iopamidol 370), applied by central pre-atrial injection. In addition, catheterization-induced complications in the venous system of the arm were studied in 130 patients. Change of heart rate was the most frequent effect observed (increase in 49% of patients pretreated with Buscopan, decrease in 36% of non-pretreated patients). The second next effects were supraventricular and ventricular ES (20%), minor prolongations of PQ and QRS intervals (14%), and ST lowering (3%), without clinical symptons. In one case, an attack of Angina pectoris was observed, another patient developed a cutane allergy. After catheterization of brachial vein, thromboses were observed in 3% of patients, as well as local inflammations in 6%, short attacks of fever in 2.3%. The complications were observed for the most part in cases where re-sterilised catheters had been used. (orig.) [de

Attenuation corrections through energy spectra analysis of whole body and partial body measurements applying gamma spectroscopy; Schwaechungskorrektur bei gammaspektroskopischen Ganz- und Teilkoerpermessungen durch Analyse der Energiespektren

Energy Technology Data Exchange (ETDEWEB)

Schelper, L.F.; Lassmann, M.; Haenscheid, H.; Reiners, C. [Wuerzburg Univ. (Germany). Klinik und Poliklinik fuer Nuklearmedizin

1997-12-01

The study was carried out within the framework of activities for testing means of direct determination of radioactivity levels in the human body due to incorporated, inhomogenously distributed radionuclides. A major task was to derive the average depth of activity distributions, particularly from photon radiation at energies below 500 keV, for the purpose of making suitable attenuation corrections. The paper presents two applicable methods which yield information on the mean depths of activity distributions, obtained through additional analyses of the energy spectra. The analyses are based on measuring the dependence of intensity of the Compton radiation on the length of pathways of the photons penetrating the soft tissue, or on measuring the energy-dependent absorption effects with photons. (orig./CB) [Deutsch] Im Rahmen der direkten Aktivitaetsbestimmung bei inhomogener Radionukliddeposition im menschlichen Koerper mittels Ganz- oder Teilkoerpermessanlagen im klinischen Bereich oder im Strahlenschutz sollte besonders bei Photonenstrahlung mit Energien von weniger als 500 keV eine Ermittlung der mittleren Tiefe der Aktivitaetsverteilung zur Schwaechungskorrektur erfolgen. Im klinischen Umfeld ist es haeufig moeglich, zur Tiefenkorrektur die mittlere Organtiefe und damit die schwaechende Gewebsschicht mittels Ultraschall zu bestimmen. Ergaenzend hierzu werden im Folgenden zwei Methoden vorgestellt, welche Aussagen ueber die mittlere Tiefe von Aktivitaetsverteilungen durch Gewinnung von Zusatzinformationen aus dem Energiespektrum im Rahmen von gamma-spektroskopischen Personenmessungen ermoeglichen. Dazu werden einerseits die Abhaengigkeit der Intensitaet der Comptonstrahlung von der Laenge der Wegstrecke von Photonen durch Weichgewebe und andererseits energieabhaengige Absorptionseffekte bei Photonen als Grundlage herangezogen. (orig.)

Radiotherapy of degenerative joint disorders. Indication, technique and clinical results; Radiotherapie bei schmerzhaften degenerativ-entzuendlichen Gelenkerkrankungen. Indikation, Technik und klinische Ergebnisse

Energy Technology Data Exchange (ETDEWEB)

Keilholz, L.; Sauer, R. [Erlangen-Nuernberg Univ. (Germany). Strahlentherapeutische Klinik und Poliklinik; Seegenschmiedt, M.H. [Erlangen-Nuernberg Univ. (Germany). Strahlentherapeutische Klinik und Poliklinik]|[Alfred-Krupp-Krankenhaus, Essen (Germany). Klinik fuer Strahlentherapie und Radioonkologie

1998-05-01

Gelenke) konnten langfristig untersucht werden, 17 Patienten mit Omarthrose (27 Gelenke), 19 mit Rhizarthrose (20 Gelenke), 31 mit Gonarthrose (49 Gelenke) und sechs Patienten mit Koxarthrose (sieben Gelenke). Die Patienten waren lange und intensiv vorbehandelt mit einer mittleren Symptomdauer von vier Jahren. Die Strahlentherapie erfolgte je nach Gelenk mit geringen technischen Unterschieden in zwei Serien (6 x 0,5 bzw. 1 Gy pro Serie in drei Fraktionen pro Woche). Die zweite Serie erfolgte sechs Wochen nach der ersten. Die mittlere Nachbeobachtungszeit betrug vier (ein bis zehn) Jahre. Vor Radiotherapie, sechs Monate danach und zum aktuellen Zeitpunkt wurde das Schmerzprofil beurteilt. 46 (63%) Patienten (64 Gelenke) sprachen auf die Therapie an; 16 dieser Patienten waren `wesentlich gebessert`, 14 `beschwerdefrei`, Knie und Schulter sprachen besser an (je 64%) als die Rhizarthrose (53%). Alle Schmerzkategorien und -grade und deren Summenscore waren ruecklaeufig. Der staerkste Rueckgang trat bei `Ruheschmerzen` ein. Alle orthopaedischen Scores korrelierten gut mit den subjektiven Angaben der Patienten. Der Daumenscore besserte sich bei elf Faellen (57%), der Schulter-Score nach Constant et al. bei 16 (59%), der Knie-Score nach Sasaki et al. bei 33 (67%), der Hueft-Score nach Harris bei fuenf (71%). 9/19 Faelle, die zur Vermeidung der Operation bestrahlt wurden, mussten operiert werden, drei davon mit Totalendoprothese. In multivariater Analyse fuer das Zielkriterium `komplette Beschwerdefreiheit` bzw. `wesentliche Besserung` der Beschwerden war die lange Symtomdauer einziger Parameter mit negativer prognostischer Bedeutung. (orig./MG)

Imaging of demyelinating and neoplastic diseases of the spinal cord; Bildgebung bei demyelinisierenden und tumoroesen Erkrankungen des Rueckenmarks

Energy Technology Data Exchange (ETDEWEB)

Mueller-Mang, C. [Institut fuer CT und MRT Gaenserndorf, Gaenserndorf (Austria)

2010-12-15

The clinical symptoms of myelopathy are variable and non-specific. Demyelinating as well as neoplastic spinal cord diseases can cause paresthesia, progressive sensomotoric deficits and bowel and bladder dysfunction. Imaging of the spine, especially with magnetic resonance imaging (MRI), is an essential component in the diagnostic assessment of myelopathy and makes a substantial contribution to achieving the correct diagnosis. Although intramedullary neoplasms are far less common than demyelinating spinal cord diseases, radiologists should be familiar with the three most common entities, astrocytoma, ependymoma and hemangioblastoma, which represent over 70% of all spinal cord neoplasms. An early diagnosis and therapy is essential with neoplastic and demyelinating spinal cord diseases to hold residual neurological deficits as low as possible. (orig.) [German] Die klinische Symptomatik von Myelopathien ist aeusserst variabel und unspezifisch. Sowohl demyelinisierende als auch tumoroese Rueckenmarkerkrankungen koennen Paraesthesien, progrediente sensomotorische Ausfaelle und eine Sphinkterdysfunktion hervorrufen. Bildgebende Untersuchungen, und hier allen voran die MRT, sind ein unerlaesslicher Bestandteil zur Abklaerung von Myelopathien und tragen wesentlich zur korrekten Diagnose bei. Intramedullaere Tumoren sind zwar weitaus seltener als demyelinisierende Rueckenmarkerkrankungen, dennoch sollte der Radiologe mit den Bildmerkmalen der 3 haeufigsten Tumorarten, dem Astrozytom, Ependymom und Haemangioblastom vertraut sein, die ueber 70% aller Rueckenmarktumoren verursachen. Eine moeglichst fruehe Diagnostik und Therapie sind bei tumoroesen und demyelinisierenden Rueckenmarkerkrankungen essenziell, um bleibende neurologische Defizite moeglichst gering zu halten. (orig.)

Nitrogen emissions during pyrolysis and combustion; Einfluesse auf die Stickstofffreisetzung bei der Pyrolyse und Verbrennung

Energy Technology Data Exchange (ETDEWEB)

Koepsel, R F; Friebel, J; Halang, S [Technische Univ. Bergakademie Freiberg (Germany). Inst. IEC

1998-09-01

Reduction of nitric oxide emissions during brown coal combustion is an important contribution to clean utilisation of this very important domestic primary energy source. In modern processes, the nitrogen contained in the fuels is the main source of oxides. The distribution of this nitrogen in the products can be influenced by modifying the degassing parameters especially in the first phase of combustion, i.e. pyrolysis. The heat-up rate, pressure, as well as the genesis and mineral content of the coal were found to be the main influencing paramters. Depending on the fuel characteristics (degree of coalification, concentration of volatile matter, ash composition), the nitrogen released during pyrolysis and the nitrogen retained in the solid residue contribute to the total emissions of nitric oxides in different degrees. (orig.) [Deutsch] Die Verminderung der Stickoxidemission bei der Verbrennung von Braunkohle stellt einen wichtigen Beitrag zur sauberen Verwertung dieses bedeutendsten einheimischen Primaerenergietraegers dar. In modernen Prozessen bildet dabei der im Brennstoff gebundene Stickstoff die Hauptquelle der Oxide. Insbesondere durch Einflussnahme auf die Entgasungsbedingungen waehrend der ersten Phase der Verbrennung - der Pyrolyse - kann die Verteilung dieses Stickstoffes auf die Produkte beeinflusst werden. Als wesentliche Einflussgroessen auf die Einbindung in den verbleibenden Koks und die Freisetzung fluechtiger N-haltiger Gase (HCN, NH{sub 3}) wurden die Aufheizgeschwindigkeit, der Druck und die Mineralsubstanz der Kohle gefunden. Eine wesentliche Einflussgroesse stellt daneben auch die Herkunft der Kohlen dar. In Abhaengigkeit von den Brennstoffeigenschaften (Inkohlungsgrad, Gehalt an fluechtigen Bestandteilen, Aschezusammensetzung) tragen der waehrend der Pyrolyse freigesetzte und der im festen Rueckstand verbleibende Stickstoff in unterschiedlichem Masse zur Gesamtemission an Stickoxiden bei. (orig.)

Rigiscan®-Monitoring der Erektion unter audiovisueller sexueller Stimulation ohne/mit Viagra™ bei Patienten mit erektiler Dysfunktion

Directory of Open Access Journals (Sweden)

Perabo FGE

2000-01-01

zwischen negativem Pharmakoduplex (keine oder geringe Erektion, ungenügende Perfusion und Mißerfolg der Viagra™-Medikation. Patienten mit einer negativen Pharmako-Testung sprachen in 60 % auf Viagra™ an. Bei positivem Pharmakoduplex ist die Wahrscheinlichkeit groß, daß auch Viagra™ erfolgreich ist. Die RigiScan®-Messung unter visueller Stimulation ohne/mit Viagra™ trägt zur einfachen Differenzierung zwischen organischer und psychogener Erektionsstörung bei. Die aufwendige Diagnostik bei der erektilen Dysfunktion kann deshalb zugunsten des RigiScan®-Monitorings unter audiovisueller Stimulation ohne/mit 50 mg Viagra™ verlassen werden.

Einsatz und Wirksamkeit von Systemtherapien bei Erwachsenen mit schwerer Neurodermitis: Erste Ergebnisse des deutschen Neurodermitis-Registers TREATgermany.

Science.gov (United States)

Schmitt, Jochen; Abraham, Susanne; Trautmann, Freya; Stephan, Victoria; Fölster-Holst, Regina; Homey, Bernhard; Bieber, Thomas; Novak, Natalija; Sticherling, Michael; Augustin, Matthias; Kleinheinz, Andreas; Elsner, Peter; Weidinger, Stephan; Werfel, Thomas

2017-01-01

Versorgungsregister dienen der Erfassung des Einsatzes und der Wirksamkeit von Therapien unter realen Versorgungsbedingungen und sind als Basis einer evidenzbasierten Gesundheitsversorgung unverzichtbar. Das deutsche Neurodermitis-Register TREATgermany wurde als weltweit erstes Register für Patienten mit schwerer Neurodermitis 2011 initiiert. Erwachsene mit schwerer Neurodermitis (aktuelle/frühere antientzündliche Systemtherapie und/oder objektiver SCORAD ≥ 40) werden über einen Zeitraum von 24 Monaten prospektiv beobachtet. Anhand validierter Erhebungsinstrumente werden die klinische Erkrankungsschwere (EASI, SCORAD), Lebensqualität (DLQI), Symptome, globale Erkrankungsschwere sowie die Patientenzufriedenheit erfasst und die durchgeführten Therapien dokumentiert. Die vorliegende Analyse beschreibt die Charakteristika, Therapiewahl und Wirksamkeit der eingesetzten antiinflammatorischen Systemtherapien der bis Oktober 2014 eingeschlossenen Patienten. An fünf Zentren wurden insgesamt 78 Patienten (Durchschnittsalter 39 Jahre, 61 % männlich) eingeschlossen. Bei den Patienten besteht eine hohe Inanspruchnahme ambulanter und stationärer Leistungen. Ciclosporin war das am häufigsten eingesetzte Systemtherapeutikum und zeigte die höchste klinische Effektivität (EASI-50-Ansprechrate 51 %; EASI-75-Ansprechrate 34 % nach zwölfwöchiger Therapie). Azathioprin, Methotrexat (MTX), Prednisolon oral, Mycophenolat, Alitretinoin und Leflunomid wurden ebenfalls bei einzelnen Patienten eingesetzt. Die vorliegende Registerauswertung gibt wichtige Hinweise zur derzeitigen Versorgung von Erwachsenen mit schwerer Neurodermitis in Deutschland, dokumentiert die hohe Erkrankungslast, den Nutzen vorhandener Therapien und den Bedarf an weiteren, effektiven und in der Langzeitanwendung sicheren Therapieoptionen. © 2017 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

PET and SPECT investigations in Alzheimer's disease; Nuklearmedizin und Demenz - Anwendung bei Morbus Alzheimer

Energy Technology Data Exchange (ETDEWEB)

Asenbaum, S. [Universitaetsklinik fuer Nuklearmedizin, Universitaetsklinik fuer Neurologie, Wien (Austria); Abteilung fuer klinische Neurologie, Universitaetsklinik fuer Neurologie, Waehringer Guertel 18-20, 1090, Wien (Austria)

2003-07-01

Nuclear medicine offers a wide range of possibilities to investigate dementia. Various SPECT and PET tracers will be introduced in this article first. Different questions concerning evaluation of dementia are discussed taking Alzheimer's disease (AD) as an example. It is important to perform nuclear medicine investigations on high technical level, using standardized methods as statistical parametric mapping (SPM) for evaluation. If neuroprotective therapies are available, an early diagnosis, the determination of risk factors and longitudinal investigations will be the focus of interest and the main goal of nuclear medicine. Apart from measuring cerebral perfusion and glucose metabolism the development of new ligands, concerning the cholinergic system and the visualization of amyloid plaques, is of great importance. (orig.) [German] Nuklearmedizin bietet bei der Erfassung und Beurteilung eines dementiellen Prozesses eine Vielzahl von Untersuchungsmoeglichkeiten. Anhand des Morbus Alzheimer (DAT) werden in dem vorliegenden Artikel neben einer kurzen Schilderung der zur Verfuegung stehenden Methoden die verschiedenen nuklearmedizinisch relevante Fragestellungen angefuehrt, zu deren Beantwortung die funktionelle Bildgebung Informationen liefern kann. Durch den Einsatz bestimmter, standardisierter Auswerteverfahren wie statistical parametric mapping (SPM) ist es moeglich, entscheidende Hinweise zur Diagnose und Differenzialdiagnose der DAT zu erlangen. In Zukunft werden, insbesondere bei einer Verfuegbarkeit neuroprotektiver Therapien, eine moeglichst fruehe Diagnosestellung und die Erfassung von Risikofaktoren sowie die Moeglichkeit einer Verlaufsbeobachtung in den Mittelpunkt des Interesses und in das Zentrum nuklearmedizinischer Untersuchungen ruecken. Vor allem fuer diese Anforderungen ist neben der qualitaetsvollen Untersuchung von zerebraler Perfusion und Glukosestoffwechsel eine Weiterentwicklung spezieller Liganden v. a. das cholinerge System betreffend und

Functional-anatomic evaluation of dilated uropathies in children using combined MR-nephrography and MR-urography compared to renal scintigraphy; Funktionell-anatomische Diagnostik dilatierter Uropathien bei Kindern mit kombinierter MR-Nephrographie und MR-Urographie im Vergleich zur renalen Isotopennephrographie

Energy Technology Data Exchange (ETDEWEB)

Reither, M. [Abt. fuer bildgebende Diagnostik am Kinderkrankenhaus Park Schoenfeld, Kassel (Germany); Tuerkay, S. [GE Medical Systems Deutschland GmbH, Solingen (Germany)

2004-02-01

Purpose: to evaluate MR-tomographic assessment of split renal function and degree of obstruction compared to diuretic renal scintigraphy, and pathoanatomic imaging of the urinary tract as all in one exam. Patients and methods: in a prospective study 62 children, aged 1 month to 9.5 years, mean 2.8 years, underwent diuretic renal scintigraphy and dynamic MR-nephrography at the same day except for 7 patients with a time interval of 1 day. In all patients we did T2w (water-technique) MR-urography additionally. Results: comparing spilt renal function we found a very close correlation in 54 out of 62 patients (correlation coefficient = 0.95). Due to technical failures 8 cases couldn't be calculated. Comparing degrees of obstruction there was an agreement in 57 out of 62 patients, 3 studies were gradually over-, 2 underestimated. All but one morphologic diagnoses in advance obtained by ultrasound and completed by other imaging modalities later on were confirmed MR-urographically. Though correctly imaged the functionless upper moiety in a renal duplication with ureterocele was misinterpreted at a first glance. (orig.) [German] Ziel: Es sollte geprueft werden, ob die Berechnung der seitengetrennten Nierenfunktion, die Bestimmung des Obstruktionsgrades und die pathoanatomische Darstellung des Harntraktes im Vergleich zur Diurese-Szintigraphie in einem Untersuchungsgang MR-tomographisch zuverlaessig moeglich ist. Patienten und Methode: In einer prospektiven Studie wurden bei 62 Kindern im Alter von 1 Monat bis 9,5 Jahren, Mittelwert 2,8 Jahre, ein Diurese-Szintigramm und eine dynamische MR-Nephrographie am gleichen Tag durchgefuehrt; lediglich bei 7 Patienten lag 1 Tag zwischen beiden Untersuchungen. Alle Patienten erhielten zusaetzlich eine T2w-MR-Urographie in ''Wasserbild''-Technik. Ergebnisse: Beim Vergleich der seitengetrennten Nierenfunktion fand sich eine sehr enge Korrelation bei 54 von insgesamt 62 Patienten (Korrelationskoeffizient = 0

Sociodemografinių charakteristikų bei organizacinių veiksnių reikšmė darbuotojų seksualinio priekabiavimo supratimui

OpenAIRE

Salygienė, Audronė

2012-01-01

Tyrimo tikslas: įvertinti sociodemografinių charakteristikų bei organizacinių veiksnių sąsajas su darbuotojų seksualinio priekabiavimo supratimu. Tyrime dalyvavo 195 tirimieji: 136 moterys ir 59 vyrai, nuo 17 iki 75 metų amžiaus (amžiaus vidurkis (28,98). Seksualinio priekabiavimo vertinimui buvo naudojama Mccabe, Hardman, (2005) adaptuota, Mazer, Percival (1989) kurta požiurio į seksualinį priekabiavimą skalė (Sexual Harassment Attitude Scale, SHAS), kuri Mccabe, Hardman, (2005) buvo p...

Malignant and benign diseases of the breast in 41 male patients: mammography, sonography and pathological correlations; Maligne und benigne Erkrankungen der Brust bei 41 maennlichen Patienten: Mammographie und Sonographie mit histopathologischer Korrelation

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Partik, B.; Mallek, R.; Pokieser, P.; Wunderbaldinger, P.; Helbich, T.H. [Vienna Univ. (Austria). Klinik fuer Radiodiagnostik; Rudas, M. [Vienna Univ. (Austria). Inst. fuer Klinische Pathologie

2001-11-01

Aim: The goal of our study was to evaluate findings in mammography and sonography in male patients with pathohistologically proven diseases of the breast. Material and Methods: Mammographies and sonographies, which were obtained in 41 male patients in a 6-year period, were retrospectively evaluated in accordance with the BI-RADS trademark classification. Results: Histologically 13 carcinomas, 21 gynecomastias, 3 pseudogynecomastias, 2 epithelial inclusion cysts and 2 other benign lesions were diagnosed. The sensitivity, specificity, positive predictive value, negative predictive value and accuracy of mammography in differentiation of benign versus malignant disease were 92%, 89%, 80%, 96% and 90%, respectively. Additional sonography did not change these results. However, sonography increased diagnostic confidence in 18.2% (2/11) of suspicious lesions. Conclusion: In our study the invasive ductal carcinoma of male patients was a predominantly lobulated, ill-defined lesion in mammography and sonography. The differentiation of carcinoma to pseudogynecomastia and diffuse or dendritic gynecomastia was securely feasible. However, we could not reliably distinguish between carcinoma and some benign mass lesions. In cases of mammographically diagnosed masses or unclear mammography, additional sonography should be performed to increase the diagnostic confidence. (orig.) [German] Ziel: Die Befunde von Mammographie und Sonographie bei histologisch gesicherten malignen und benignen Mammaerkrankungen maennlicher Patienten zu evaluieren. Material und Methode: Retrospektiv wurden die in einem Zeitraum von 6 Jahren durchgefuehrten Mammographien und Sonographien bei 41 maennlichen Patienten in Anlehnung an die BI-RADS trademark Klassifikation ausgewertet. Resultate: Es wurden 13 Karzinome, 21 Gynaekomastien, 3 Pseudogynaekomastien, 2 Atherome und 2 weitere benigne Laesionen histologisch diagnostiziert. Die Mammographie zeigte in der Differenzierung maligne versus benigne Laesion

Dominanzverhalten bei Przewalskipferden in seminatürlicher Haltung im Kölner Zoo unter besonderer Berücksichtigung der Körpersprache

OpenAIRE

Herberz, S.

2011-01-01

Dominanzverhalten sichert die soziale Rangordnung innerhalb einer Pferdeherde und trägt so zur friedlichen Konfliktlösung bei. Die Körpersprache ist hierbei mit festgelegten Droh- und Unterwerfungsgesten ein wichtiges Kommunikationsmittel. Im Rahmen dieser Arbeit wurden Beobachtungen an der Przewalskipferd-Herde des Kölner Zoos durchgeführt. Dabei wurde die Körpersprache der Wildpferde analysiert und ihr Dominanzverhalten auf Abhängigkeit von Situation und Alterskonstellation untersucht.

Individuelle Migrationsentscheidungen am Beispiel polnischer Migranten in Baden-Württemberg : eine Untersuchung zum individuellen Entscheidungsverhalten bei transnationaler Mobilität

OpenAIRE

Seyffer, Silke

2013-01-01

Die vorliegende Studie behandelt die Frage, wie sich Individuen für eine nicht nur kurzzeitige transnationale Migration entscheiden: Geschieht dies nach rationalen Gesichtspunkten, nach objektivierbaren Kriterien mit einer Fülle von Informationen und durchdachtem Plan oder handelt es sich um spontane, subjektive Entscheidungen, bei denen Informationssuche und strukturierte Überlegungen im Vorfeld keine wichtige Rolle spielen? Eingangs werden für die Studie relevante Entscheidungs- und Mig...

UMA ANÁLISE CRÍTICA ENTRE OS CURRÍCULOS DOS CURSOS DE CIÊNCIAS CONTÁBEIS NOS PAÍSES DO MERCOSUL E O PROPOSTO PELA ONU/UNCTAD/ISAR

Directory of Open Access Journals (Sweden)

Giovanna Tonetto Segantini

2013-07-01

Full Text Available A harmonização das normas contábeis tornou-se uma necessidade dos usuários externos e in-ternos da informação contábil, uma vez que passaram a atuar em diversos mercados e a prestar contas aos usuários com necessidades variadas, pois o mercado cada vez mais globalizado exige profissionais preparados para atuar dentro e fora do seu país. Visando isso, a ONU/UNCTAD/ISAR desenvolveu um Currículo Mundial para servir de referência para os cursos de Ciências Contábeis, buscando prover conhecimentos internacionais de normas contábeis independentemente do país responsável pela formação do profissional. Assim, o objetivo geral do artigo foi analisar e comparar a adequação dos currículos dos cursos de ciências contá-beis de quatro universidades do MERCOSUL, sendo uma de cada país, com o currículo proposto pela ONU/UNCTAD/ISAR. As universidades selecionadas foram: Facultad de Ciencias Econômicas de la Universidad de Buenos Aires (Argentina; Faculdade de Economia, Administração e Con-tabilidade da Universidade de São Paulo (Brasil; Universidad Nacional de Asunción (Paraguai; e Facultad de Ciências Econômicas y de Administración de la Universidad de la República (Uruguai, e suas matrizes curriculares foram comparadas com o Currículo Mundial proposto pela ONU/UNCTAD/ISAR. Os resultados indicam que a similaridade entre os currículos das quatro universidades selecionadas com o proposto pela ONU/UNCTAD/ISAR é alta, existindo, em mé-dia, 76,71% de semelhança entre as matérias dos currículos. Por ser apenas uma recomendação, as universidades pesquisadas demonstraram possuir certa flexibilidade na elaboração de seus currículos.

MRI of interstitial lung diseases. What is possible?; MRT bei interstitiellen Lungenerkrankungen. Was ist moeglich

Energy Technology Data Exchange (ETDEWEB)

Biederer, J. [Kreisklinik Gross-Gerau, Radiologie Darmstadt, Gross-Gerau (Germany); Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Deutsches Zentrum fuer Lungenforschung (DZL), Translational Lung Research Center (TLRC) Heidelberg, Heidelberg (Germany); Thoraxklinik, Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Heidelberg (Germany); Wielpuetz, M.O.; Jobst, B.J.; Dinkel, J. [Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie, Heidelberg (Germany); Deutsches Zentrum fuer Lungenforschung (DZL), Translational Lung Research Center (TLRC) Heidelberg, Heidelberg (Germany); Thoraxklinik, Universitaetsklinikum Heidelberg, Klinik fuer Diagnostische und Interventionelle Radiologie mit Nuklearmedizin, Heidelberg (Germany)

2014-12-15

interstitieller Lungenerkrankungen die groesste Herausforderung dar. Zusammenfassung des aktuellen Stands zu Moeglichkeiten und Perspektiven der MRT fuer die Diagnostik interstitieller Lungenerkrankungen. Zusammenfassung einer aktuellen Literaturrecherche und Bewertung der Ergebnisse vor dem Hintergrund eigener Erfahrungen mit der Lungen-MRT. Allein aufgrund der geringeren Detailaufloesung und der deutlich groesseren Anfaelligkeit fuer Artefakte ist die MRT der CT bei der Diagnostik interstitieller Lungenerkrankungen (''interstitial lung diseases'', ILD) bei feinen Mustern (feinnetzige Fibrose, Mikronoduli) unterlegen, kann aber groebere Fibrosen (Honigwabenmuster) detektieren. Zudem wurde an kleinen Fallgruppen gezeigt, dass die MRT diagnostisch wertvolle Informationen zur regionalen Lungenfunktion (Ventilation, Perfusion, mechanische Eigenschaften) und Entzuendungsaktivitaet (natives Signal, Kontrastmitteldynamik) liefern kann. Aktuell kann die morphologische Lungen-MRT ergaenzend zur kardialen Diagnostik bei Sarkoidose fuer die umfassende kardiothorakale Bildgebung in einer Sitzung oder fuer Verlaufsbeobachtungen eingesetzt werden. Wenn sich die Moeglichkeiten der MRT-basierten Lungenfunktionsdiagnostik und Beurteilung der Entzuendungsaktivitaet klinisch robust umsetzen lassen, ist von einer deutlichen Erweiterung des Anwendungsspektrums auszugehen. (orig.)

Value of breast MRI as supplement to mammography and sonography for high risk breast cancer patients; Wertigkeit der Mamma-MRT als Ergaenzung zu Mammographie und Sonographie bei Patientinnen mit erhoehtem Mammakarzinomrisiko

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Schlossbauer, T.; Hellerhoff, K.; Reiser, M. [Klinikum Grosshadern der Ludwig-Maximilians-Universitaet Muenchen, Institut fuer Klinische Radiologie, Muenchen (Germany)

2008-04-15

The aim of this study is to give an overview on early detection of breast cancer in patients with an increased risk of breast cancer. Sensitivities and diagnostic accuracies of breast MRI, mammography and ultrasound were compared. A systematic literature search of the past 3 years was performed. Studies which compared breast imaging modalities and used image-guided biopsy results as standard of reference were included. Patients included had to have had an increased lifetime risk for breast cancer (>15%). Regarding sensitivity and diagnostic accuracy, breast MRI performed best in comparison to the other modalities within this collective of patients. Sensitivities ranged from 71-100%, 0-78%, and 13-65%, for MRI, mammography, and ultrasound, respectively Breast MRI is a well established tool for screening in patients at high risk for developing breast cancer and is a valuable supplement to mammography and ultrasound within this selected cohort of patients. (orig.) [German] Ziele der Arbeit sind die inhaltliche Einfuehrung in das Thema Frueherkennung des Mammakarzinoms bei Patientinnen mit erhoehtem Risiko und eine systematische Analyse der Wertigkeit von MRT und anderen bildgebenden Verfahren in diesem Zusammenhang. Es wurde eine systematische Literaturrecherche ueber die letzten 3 Jahre durchgefuehrt. Dabei wurden Vergleichsstudien der verschiedenen bildgebenden Verfahren in der Mammadiagnostik beruecksichtigt, bei denen die bildgesteuerte Biopsie als Goldstandard angegeben wurde. Von allen bildgebenden Verfahren zeigt die Mamma-MRT bei Patientinnen mit familiaerem Risiko die hoechste Sensitivitaet und diagnostische Genauigkeit bei der Detektion des Mammakarzinoms. Fuer MRT, Mammographie und Sonographie werden Sensitivitaeten zwischen 71 und 100%, 0 und 78% sowie 13 und 65% angegeben. Die Mamma-MRT ist ein etabliertes Verfahren zum Screening von Risikopatientinnen. Uebereinstimmend wird der diagnostische Nutzen der Mamma-MRT als ergaenzendes Verfahren zu Mammographie

Hydro-MRI for abdominal diagnostics in children; Hydro-MRT in der Darmdiagnostik bei Kindern

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Kern, A.; Schunk, K.; Oberholzer, K.; Thelen, M. [Mainz Univ. (Germany). Klinik und Poliklinik fuer Radiologie; Kessler, M. [Mainz Univ. (Germany). Klinik und Poliklinik fuer Kinderchirurgie

2001-11-01

A clinical evaluation of hydro-MRI as an alternative method to barium studies in children with abdominal pain of unknown origin is presented. Patients and Methods: 20 children with abdominal pain of unknown origin aged from 9 - 16 years were examined after oral bowel opacification using 1000 ml of 2.5% mannitol solution with a 1.0T MRI system. The investigation was done in 2 planes (coronal and axial) under breath-hold conditions. Imaging procedures included various sequences (T2W HASTE + FS, contrast-enhanced T1W FLASH FS). Suspicious findings in bowel segments and extra-intestinal changes were assessed. Results: In 21/24 examinations the small bowel was completely visualized, in 15/24 cases colon segments were identified. An accurate assessment of the terminal ileum was not possible in 3/24 procedures. Breathing artefacts occurred in 3/24 examinations. Signs of Crohn's disease were found in 4 examinations, inflammatory changes of the ileum were detected in 3 cases. Inflammation of the colon was demonstrated in 2 children. Furthermore, pathological findings included constipation in one child and inflammation of the ileo-colic and mesenterial lymph nodes were found in another child. Extra-intestinal changes in 3 children were caused by ovarian cysts, and in one case by pleural effusion. In 4 examinations we detected ascites in the absence of other pathological findings. In 5 children there was no pathological correlation in the bowel or extra-intestinal region for the complaints. The children tolerated the hydro-MRI very well. There were no side effects using oral mannitol. (orig.) [German] Ziel: Klinische Evaluation der Hydro-MRT bei Kindern mit unklarer abdomineller Symptomatik als alternative Methode zur fraktionierten Magen-Darm-Passage. Patienten und Methoden: 20 Kinder und Jugendliche im Alter von 9 bis 16 Jahren mit unklaren abdominellen Beschwerden bzw. mit Verdacht auf eine chronisch entzuendliche Darmerkrankung wurden nach einer oralen

Possibilities for exposure reduction in computed tomography examination of acute chest pain; Moeglichkeiten der Dosisreduktion bei CT-Untersuchungen des akuten Thoraxschmerzes

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Becker, H.C. [Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Campus Grosshadern, Institut fuer Klinische Radiologie, Muenchen (Germany)

2012-10-15

Electrocardiogram-gated (ECG) computed tomography (CT) investigations can be accompanied by high amounts of radiation exposure. This is particularly true for the investigation of patients with unclear and acute chest pain. The common approach in patients with acute chest pain is standard spiral CT of the chest. The chest pain or triple-rule-out CT protocol is a relatively new ECG-gated protocol of the entire chest. This article reviews and discusses different techniques for the CT investigation of patients with acute chest pain. By applying the appropriate scan technique, the radiation exposure for an ECG-gated protocol must not necessarily be higher than a standard chest CT scan Aortic pathologies are far better depicted by ECG-gated scan protocols and depending on the heart rate coronary artery disease can also be detected at the same time. The use of ECG-triggered scans will not support the diagnostics of the pulmonary arteries. However, in unspecific chest pain an ECG-triggered scan protocol can provide information on the differential diagnosis. (orig.) [German] EKG-getriggerte CT-Untersuchungen koennen mit einer relativ hohen Strahlenexposition einhergehen. Dies gilt im besonderen Masse fuer die Untersuchung des gesamten Thorax bei Patienten mit unklarem akutem Thoraxschmerz. Bisher wurden Untersuchungen bei Patienten mit akutem Thoraxschmerz in Spiraltechnik ohne EKG-Triggerung durchgefuehrt. Das ''Chest-pain-'' oder ''Triple-rule-out''-Protokoll ist ein neues EKG-getriggertes Untersuchungsprotokoll des gesamten Thorax. Im vorliegenden Artikel werden verschiedene Techniken zur CT-Untersuchung von Patienten mit akutem Thoraxschmerz vorgestellt und besprochen. Mit der richtigen Untersuchungstechnik muss die Strahlenexposition fuer ein EKG-getriggertes Untersuchungsprotokoll nicht hoeher sein als eine Standarduntersuchung ohne EKG. Mit einem EKG-getriggerten Untersuchungsprotokoll laesst sich die Aorta in Hinblick auf

MR-myelography in patients with spinal canal stenosis; MR-Myelographie bei Spinalkanalstenosen

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Freund, M.; Hutzelmann, A.; Steffens, J.C.; Heller, M. [Klinik fuer Radiologische Diagnostik, Christian-Albrechts-Universitaet zu Kiel (Germany); Buhl, R. [Klinik fuer Neurochirurgie, Christian-Albrechts-Universitaet zu Kiel (Germany)

1997-11-01

Purpose: The purpose of this prospective study was to evaluate the clinical value of 3D-MR-myelography (3D-MRM) in comparison to myelography and intra-operative findings. Material and Methods: 25 patients with suspected lumbar spinal canal stenosis were studied via myelography and 3D-MRM (volume-data set, 3D-FISP sequenz, T{sub R} 73 ms, T{sub E} 21 ms, flipangle 7 , sagittal slices) besides the routinely acquired sagittal and axial T{sub 1}- and T{sub 2}-weighted images. Diagnoses were made by two radiologists and one neurosurgeon without knowing the clinical history and symptoms, in two separate sessions. Results were compared to intraoperative findings. Results: 3D-MRM has the same diagnostic sensitivity (25/25=100%) as conventional X-ray myelography (25/25=100%) compared to intraoperative findings, but is not invasive and shows more diagnostic details than myelography. Especially in cases of high-grade spinal canal stenosis there is often a lack of intrathecal contrast medium distally of the stenosis. (orig./AJ) [Deutsch] Ziel: Bewertung der 3D-MR-Myelographie (3D-MRM) in der Diagnostik lumbaler Spinalkanalstenosen im Vergleich zu Myelographie und Korrelation mit intraoperativem Befund. Material und Methode: In einer fortlaufenden, prospektiven Studie wurden 25 Patienten mit den Symptomen einer lumbalen Spinalkanalstenose kernspintomographisch untersucht. Neben den ueblichen sagittalen und axialen T{sub 1}- und T{sub 2}-gewichteten Aufnahmen wurde ein Volumendatensatz mit einer 3D-FISP Sequenz (T{sub R} 73 ms, T{sub E} 21 ms, Flipwinkel 7 ) akquisiert. Die Nachverarbeitung erfolgte mittels Maximum Intensitaets-Projektion (MIP): 18 Projektionen von 0 -180 . Die 3D-MRM wurde der Myelographie gegenuebergestellt, beide Untersuchungen wurden getrennt von drei Untersuchern blind ausgewertet. Ergebnisse: Sowohl die 3D-MRM als auch die der Myelographie zeigten bei Patienten mit lumbaler Spinalkanalstenose in Korrelation zum intraoperativen Befund eine Uebereinstimmung

O Valor Adicionado dos Cursos de Ciências Contábeis: um Estudo na Região Sudeste do Brasil

Directory of Open Access Journals (Sweden)

Silvana Cristina dos Santos

2015-01-01

Full Text Available Nos últimos anos, a profissão contábil tem passado por diversasmudanças. O papel do contador na sociedade tem evoluído,tornando a sua função mais sofisticada e sua formaçãoacadêmica primordial para a execução das tarefas das empresas.Nesse contexto, este artigo busca identificar os fatores queexplicam o Valor Adicionado pelas Instituições de EnsinoSuperior aos alunos do curso de Ciências Contábeis. Para tanto,utiliza-se os resultados da prova de conhecimentos específicosdo Exame Nacional de Desempenho de Estudantes (Enade2009, tendo como amostra 251 cursos de Ciências Contábeis daregião Sudeste. Na análise empírica dos dados, fez-se uso dasestatísticas descritivas e de modelos de regressão linear. Combase na metodologia do valor adicionado, aplicou-se a teoria daFunção de Produção, controlando-se características individuaise socioeconômicas dos alunos. Os resultados sugerem que osprincipais determinantes do Valor Adicionado são os seguintes:a existência de um plano de ensino, a quantidade de alunos querecebem bolsas de estudos e o tamanho do corpo discente.

Familienbezogene Lebensqualität bei Müttern von Jungen mit Fragilem-X-Syndrom im frühen Kindesalter

OpenAIRE

Sarimski, Klaus

2010-01-01

Die Erfassung familienbezogener Lebensqualität bei Müttern behinderter Kinder richtet sich sowohl auf Einschränkungen, die mit der Erziehung und Versorgung des Kindes für das eigene Leben verbunden sind, wie auch mögliche positive Veränderungen der eigenen Perspektiven. Es ist davon auszugehen, dass die Lebensqualität u. a. vom Alter des Kindes und der Art seiner Behinderung abhängt. Es wird über eine Untersuchung mit dem Fragebogen zur familienbezogenen Lebensqualität (FLQ) berichtet, in der...

Pre- and post-operative evaluation of ventricular function, muscle mass and valve morphology by MR tomography in Ebstein's anomaly; Prae- und postoperative Beurteilung der ventrikulaeren Funktion, Muskelmasse und Klappenmorphologie bei der Ebstein-Anomalie mit der Magnetresonanztomographie

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Gutberlet, M.; Oellinger, H.; Amthauer, H.; Hoffmann, T.; Felix, R. [Charite-Campus Virchow, Berlin (Germany). Klinik fuer Strahlenheilkunde; Ewert, P.; Nagdyman, N.; Lange, P. [Deutsches Herzzentrum Berlin (Germany). Abt. fuer Angeborene Herzfehler/Kinderkardiologie; Hetzer, R. [Deutsches Herzzentrum Berlin (Germany). Abt. fuer Herz-, Thorax- und Gefaesschirurgie

2000-05-01

Purpose: To evaluate the value of MRT with spin echo (SE) and CINE gradient echo (GE) sequences for the pre- and postoperative assessment of patients with Ebstein's anomaly. Methods: Twelve patients within the ages of four to 49 years (mean 22{+-}12 years) were examined pre- (n=5) or postoperatively (n=7) after tricuspid valve reconstruction with a 1.5 T scanner. For the anatomical assessment, an ECG-gated transverse SE-sequence, for the assessment of valve morphology and function as well as for volumetry a CINE GE-sequence with retrospective gating was used. With the use of the multislice-multiphase technique, after summing up the manually outlined epi- and endocardial areas, endsystolic (ESV) and enddiastolic volumes (EDV), ejection fraction (EF), stroke volume (SV), and muscle mass (MM) were calculated for both ventricles. Results: The differentiation of the displaced parts of the tricuspid valve (TV) was insufficient with static SE, but was possible in all patients with CINE-MRT. Like in Doppler echocardiography, a qualitative assessment of tricuspid insufficiency was possible in CINE-MRT, the mean incompetence grade preoperative was 1.8 ({+-}0.8), postoperative 0.7 ({+-}0.5). The mean RV-EF in the preoperative group was 41.8% ({+-}6.4), in the postoperative group 47.9% ({+-}10.6), the mean LV-EF preoperative 47.4% ({+-}8.5%), postoperative 63,0% ({+-}9.4). Conclusion: CINE-MRT should rather be used than SE for the assessment of valve morphology. EF, muscle mass and tricuspid incompetence can also be calculated pre- and postoperative with CINE-MRT. (orig.) [German] Zielsetzung: Zu ermitteln, welchen Beitrag die MRT mit der Spin-Echo-(SE) bzw. CINE-Gradienten-Echo-Sequenz (GE) zur prae- und postoperativen Beurteilung bei Patienten mit Ebstein-Anomalie leisten kann. Material und Methode: Es wurden 12 Patienten im Alter zwischen 4 und 49 Jahren (im Mittel 22{+-}12 Jahre) prae- (n=5) oder postoperativ (n=7) nach einer Trikuspidalklappenkonstruktion an einem 1

Pengaruh Pengungkapan Intellectual Capital (IC dan Economic Value Added (EVA terhadap Harga Saham Perusahaan Manufaktur yang terdaftar di BEI

Directory of Open Access Journals (Sweden)

Achmad Fauzi

2015-07-01

Full Text Available This study aims at finding out if The Influence of Intellectual Capital (ICand Economic Value Added (EVA on Stock Price of Manufacturing Companies listed on the Indonesia Stock Exchange (BEI in 2012. The hypothesis of this study is : There is Influence of Intellectual Capital (IC and Economic Value Added (EVA on Stock Price of Manufacturing Company listed on the Indonesia Stock Exchange (BEI in 2012. The method used is the author of the survey method with a quantitative approach . This study population is the entire manufacturing companies listed on the Stock Exchange in 2012 his sampling technique is random sampling as many as 36 samples .. Correlation Coefficient significance test ( Test A of 0.512 , indicating that there is a middle relationship between IC and EVA on Stock Price. The results of the coefficient of determination ( R2 Test stated that R2 is 0.262 or 26.2% . This shows that the percentage contribution of the effect of independent variables ( IC and EVA on the dependent variable ( stock price of 26.2 % . Or variations of the independent variables used in the model ( IC and EVA are able to explain 26.2% of variation in the dependent variable ( stock price . While the remaining 73.8 % are influenced or explained by other variables not included in this research model .

Conventional X-ray examination and computed tomography in inflammatory rheumatic diseases; Roentgendiagnostik und Computertomographie bei entzuendlich-rheumatischen Erkrankungen

Energy Technology Data Exchange (ETDEWEB)

Lingg, G. [Rheumazentrum Bad Kreuznach (Germany). Zentrales Roentgeninstitut

1996-08-01

Plain-film radiography is an important and basic element in the assessment of inflammatory rheumatic diseases. Its various uses include assessment of inflammatory osseous destruction and the activity of inflammatory changes. Furthermore, the inflammatory collateral phenomena can indicate an acute clinical phase, and the articular soft tissue swelling and tenosynovitis are shown directly and indirectly very clearly. On the other hand, high-resolution computed tomography is very capable of showing cortical structures of bone complementary to MR. In some special clinical questions and anatomical regions, especially the axial skeleton, it delivers information of high specifity, partly for definitive diagnosis and partly for planning surgical procedures. The assessment of changes in the sacroiliac joints, sternoclavicular joints and craniocervical junction are domains of computed tomography. (orig.) [Deutsch] Das konventionelle Roentgenbild muss auch heute noch bei klinischer Frage nach entzuendlich-rheumatischer Erkrankung als Basisuntersuchung angesehen werden. Sein Informationspotential umfasst nicht nur knoecherne entzuendliche Destruktionen, sondern es laesst auch deren derzeitige Aktivitaet beurteilen. Weiterhin vermag das Roentgenbild ueber die Kollateralphaenomene auf eine klinische Schubsituation hinzuweisen und die entzuendliche Volumenvermehrung der Gelenke und Sehnenscheiden direkt und indirekt darzustellen. Darueber hinaus bietet die hochaufloesende Computertomographie, insbesondere durch die detaillierte Darstellung kortikaler knoecherner Strukturen - komplementaer zur MR -, bei einigen speziellen Fragestellungen, insbesondere am Stammskelett und an einzelnen grossen Gelenken, hochspezifische Informationen, teils zur definitiven Diagnosestellung, teils auch fuer die Operationsplanung. Dies gilt u.a. fuer die Kreuzdarmbeingelenke, die Sternoklavikulargelenke und die obere HWS. (orig.)

Gerbstoffe aus Potentilla officinalis wirken entzündungshemmend im UV-Erythem-Test und bei Anwendung auf atopischer Haut.

Science.gov (United States)

Hoffmann, Julia; Wölfle, Ute; Schempp, Christoph M; Casetti, Federica

2016-09-01

Das Rhizom von Potentilla officinalis (PO) ist reich an Gerbstoffen und wird traditionell zur äußerlichen Behandlung von Entzündungen der Haut und der Schleimhäute verwendet. Ziel der vorliegenden Arbeit war die Bestätigung der antiinflammatorischen Eigenschaften von PO mittels eines UV-Erythem-Tests und einer klinischen Anwendungsstudie bei atopischer Haut. Die antiinflammatorische Wirkung eines PO-Extrakts (standardisiert auf 2 % Trockensubstanz) wurde in einer prospektiven, randomisierten, placebokontrollierten Doppelblindstudie mit 40 gesunden Erwachsenen im UV-Erythem-Test im Vergleich zu 1 % Hydrocortisonacetat untersucht. Im Rahmen einer prospektiven nicht kontrollierten Studie wurde die Wirkung und Verträglichkeit der 2 % PO-Creme an zwölf Erwachsenen und zwölf Kindern mit atopischer Haut nach Anwendung über zwei Wochen in einem definierten Testareal anhand eines Teil-SCORAD untersucht. Zusätzlich wurde die Beeinflussung der Hautrötung im Testareal photometrisch gemessen. Im UV-Erythem-Test zeigte die PO-Creme eine signifikante Reduktion des Erythemindex im Vergleich zum Vehikel. Die antiinflammatorische Wirkung des Verums entsprach der der 1 % Hydrocortisonacetat-Creme. Die klinische Studie bei Atopikern zeigte eine signifikante Abnahme des Teil-SCORAD und des Erythems im Testareal. Es wurden keine Unverträglichkeitsreaktionen beobachtet. PO als 2%ige Zubereitung besitzt entzündungshemmende Eigenschaften und ist wirksam und gut verträglich auf atopischer Haut. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

CT urography in women with primary or recurrent pelvic tumors. Background and initial experiences; CT-Urographie bei Frauen mit primaeren oder rezidivierenden Beckentumoren. Hintergrund und erste Erfahrungen

Energy Technology Data Exchange (ETDEWEB)

Seifert, S.; Mueller-Lisse, U.G.; Degenhart, C.; Mourched, F.; Reiser, M.F. [Klinikum der Ludwig-Maximilians-Universitaet, Campus Innenstadt, Institut fuer Klinische Radiologie, Muenchen (Germany); Jundt, K. [Klinikum der Ludwig-Maximilians-Universitaet, Campus Innenstadt, Klinik und Poliklinik fuer Gynaekologie und Geburtshilfe, Muenchen (Germany); Stief, C.G.; Mueller-Lisse, U.L. [Klinikum der Ludwig-Maximilians-Universitaet, Campus Innenstadt, Klinik und Poliklinik fuer Urologie, Muenchen (Germany)

2011-07-15

Malignant tumors of the female pelvis account for 12-13% of newly diagnosed solid neoplasms among women in the USA and Germany. German guidelines advocate diagnostic imaging for local recurrence and metastasis while there are no recommendations for primary tumors. As excretory urography has been replaced by the excretory phase of computed tomography urography (CTU) in many institutions, two independent observers retrospectively evaluated CTUs of primary or recurrent female pelvic tumors to rule out associations between CTU findings and subsequent urologic measures. Among 31 CTUs of 27 women (age 29-84 years, mean 57 years) with 15 primary and 13 recurrent tumors, 83-100% of unremarkable proximal, middle and distal ureter segments were completely delineated in the excretory phase (delay 6-29 min, mean 16 min). The most common pathological findings included distal ureter obstruction (n=19, 61%), bladder compression (n=13, 42%) and bladder invasion (n=8, 26%). Out of 20 pathologically altered urinary tracts 8 were subsequently subjected to urologic measures (2-tailed Fisher exact test, p=0.0215) but none of the 10 unremarkable urinary tracts were treated. It appears that CTU is a sensible pre-therapeutic test for the urinary tract for primary and recurrent female pelvic tumors. (orig.) [German] Maligne Beckentumoren stellen 12-13% aller neu diagnostizierten soliden Neoplasien bei Frauen in den USA und in Deutschland dar. Deutsche Leitlinien befuerworten bildgebende Untersuchungen bei Lokalrezidiven und Metastasen; fuer Primaertumoren gibt es keine einschlaegigen Empfehlungen. Da das Ausscheidungsurogramm durch die Ausscheidungsaufnahme der CT-Urographie (CTU) weitgehend abgeloest ist, wurde bei weiblichen Beckentumoren oder deren Rezidive der Zusammenhang zwischen CTU-Befunden und nachfolgenden operativen urologischen Massnahmen retrospektiv von 2 unabhaengigen Auswertern geprueft. Bei 31 CTUs von 27 Frauen (Alter 29-84, Median 57 Jahre) mit 15 Primaertumoren und 13

External therapy with radioactive urine: a pitfall during sceletal scintigraphy; Heisse Eigenurintherapie: ein ueberraschender Befund bei der Skelettszintigraphie

Energy Technology Data Exchange (ETDEWEB)

Scheidhauer, K.; Urbannek, V. [Klinik und Poliklinik fuer Nuklearmedizin, Univ. Koeln (Germany)

1997-12-01

A 41-year old male patient suffering from psoriasis arthropathica underwent a two-phase bone scan for activity of joint affections. Extensive diffuse skin contamination of the extremities in the delayed images was due to the use of the patient`s own radioactive urine as an embrocation for psoriasis exanthema. (orig.) [Deutsch] Bei einem 41jaehrigen Patienten mit Psoriasisarthropathie fiel in der Skelettszintigraphie in den Aufnahmen der Mineralisationsphase eine flaechige Aktivitaetsbelegung der Beine auf. Als Ursache stellte sich das zwischenzeitliche Einreiben der Extremitaeten durch den Patienten mit dem radioaktiven Eigenurin wegen eines Exantherms heraus. (orig.)

Dust abatement in mining and tunnelling - status report; Stand der Technik bei der Staubbekaempfung im Berg- und Tunnelbau

Energy Technology Data Exchange (ETDEWEB)

Mikki, P. [CFT GmbH, Compact-Filtertechnik, Gladbeck (Germany)

2005-02-01

Health and safety have priority in underground mining, especially dust and silicosis prevention in mining and tunnelling. While silicosis is not considered as an occupational disease in the strict sense, it is well known that most silicosis cases occur in these industries. (orig.) [German] Im Untertagebau sind die Probleme des Gesundheitsschutzes von vorrangiger Bedeutung, insbesondere im Bereich der Staub- und Silikosebekaempfung im Berg- und Tunnelbau. Wenn auch bei der Silikose nicht ausschliesslich von einer unter Tagespezifischen Berufskrankheit gesprochen werden kann, so entfaellt doch der ueberwiegende Teil der auftretenden Krankheitsfaelle auf diese Industriezweige. (orig.)

Temporary balloon occlusion as therapy for uncontrollable arterial hemorrhage in multiply injured patients; Temporaere Ballonokklusion als Therapie unkontrollierbarer arterieller Blutungen bei Polytraumapatienten

Energy Technology Data Exchange (ETDEWEB)

Rieger, J.; Linsenmaier, U.; Rock, C.; Pfeifer, K.J. [Abt. fuer Radiologie, Klinikum Innenstadt, Ludwig-Maximilian-Univ., Muenchen (Germany); Euler, E. [Chirurgische Klinik und Poliklinik, Klinikum Innenstadt, Ludwig-Maximilian-Univ., Muenchen (Germany)

1999-01-01

Purpose: Presentation of temporary balloon occlusion as an interventional radiological method for managing hemorrhage in multiply injured patients with uncontrollable loss of blood. Method: Temporary, non-selective arterial occlusion by introduction of a balloon catheter contralaterally to the source of bleeding has been performed since 1992 on 7 patients with multiple injuries, hemorrhagic shock requiring reanimation, and angiographic demonstration of an arterial hemorrhage in the supply region of the internal iliac artery with complex pelvic fracture. In each case a PTA balloon catheter was introduced transfemorally, non-selectively positioned proximal to the bleeding source, and left in place for 24-48 h under manometric control. Control angiographies were performed prior to catheter removal. Results: The bleeding was stopped immediately in all 7 patients. The hemodynamic stability made transport and thus further surgical management and/or a short-term treatment in the intensive-care station possible. Control angiographies confirmed that the bleeding had stopped in all patients. Conclusions: We recommend temporary balloon occlusion as a rapid and effective method for the management of bleeding in otherwise uncontrollable traumatic hemorrhages in the supply region of the internal iliac artery. (orig.) [Deutsch] Ziel: Vorstellung der temporaeren Ballonokklusion als interventionell-radiologischer Methode zur Blutungskontrolle bei Polytraumapatienten mit unkontrollierbarem Blutverlust. Methode: Temporaerer, nicht-selektiver arterieller Gefaessverschluss mit kontralateral der Blutungsquellen eingefuehrten PTA-Ballonkathetern bei seit 1992 insgesamt 7 Patienten mit Polytrauma, reanimationspflichtigem haemorrhagischem Schock und angiographischem Nachweis einer arteriellen Blutung im Versorgungsgebiet der A. iliaca interna im Rahmen einer komplexen Beckenfraktur. Transfemoral wurde jeweils ein PTA-Ballonkatheter eingefuehrt, nicht selektiv proximal der Blutungsquelle

Gas hydrates in gas storage caverns; Gashydrate bei der Gaskavernenspeicherung

Energy Technology Data Exchange (ETDEWEB)

Groenefeld, P. [Kavernen Bau- und Betriebs-GmbH, Hannover (Germany)

1997-12-31

Given appropriate pressure and temperature conditions the storage of natural gas in salt caverns can lead to the formation of gas hydrates in the producing well or aboveground operating facilities. This is attributable to the stored gas becoming more or less saturated with water vapour. The present contribution describes the humidity, pressure, and temperature conditions conducive to gas hydrate formation. It also deals with the reduction of the gas removal capacity resulting from gas hydrate formation, and possible measures for preventing hydrate formation such as injection of glycol, the reduction of water vapour absorption from the cavern sump, and dewatering of the cavern sump. (MSK) [Deutsch] Bei der Speicherung von Erdgas in Salzkavernen kann es unter entsprechenden Druck- und Temperaturverhaeltnissen zur Gashydratbildung in den Foerdersonden oder obertaegigen Betriebseinrichtungen kommen, weil sich das eingelagerte Gas mehr oder weniger mit Wasserdampf aufsaettigt. Im Folgenden werden die Feuchtigkeits-, Druck- und Temperaturbedingungen, die zur Hydratbildung fuehren erlaeutert. Ebenso werden die Verringerung der Auslagerungskapazitaet durch die Hydratbildung, Massnahmen zur Verhinderung der Hydratbildung wie die Injektion von Glykol, die Verringerung der Wasserdampfaufnahme aus dem Kavernensumpf und die Entwaesserung der Kavernensumpfs selbst beschrieben.

Identificação de indicadores contábeis relevantes para previsão e projeção de rentabilidade

Directory of Open Access Journals (Sweden)

Andrei Aparecido de Albuquerque

2010-12-01

Full Text Available Vários estudos utilizando indicadores contábeis para a previsão de insolvência têm sido desenvolvidos desde as décadas de sessenta e setenta. Esses trabalhos buscam prever um possível estado de deterioração do desempenho financeiro das empresas, utilizando-se de modelos estatísticos. A presente pesquisa buscou identificar quais os indicadores contábeis mais significativos para a previsão de rentabilidade das empresas, propondo uma função que utilize indicadores passados como base para prever rentabilidade futura. Foram empregadas informações de todas as empresas não financeiras que estavam ativas e possuíam ações negociadas na Bolsa de Valores de São Paulo (Bovespa nos anos de 2004, 2003 e 2002. Utilizando-se a análise descritiva e empregando o modelo de regressão linear múltipla, verificaram-se quais foram as variáveis mais significativas com suas respectivas Ponderações. Conclui-se com uma função de previsão de ROA, contendo cinco variáveis independentes estatisticamente significantes ao nível de 5% (cinco porcento das doze selecionadas para o modelo inicial.

Power plant investment cycles in liberalised markets. A model of the German electricity generation market; Zyklen bei Kraftwerksinvestitionen in liberalisierten Maerkten. Ein Modell des deutschen Stromerzeugungsmarktes

Energy Technology Data Exchange (ETDEWEB)

Gaidosch, Lars

2008-07-01

In the course of the next ten to fifteen years almost half of Germany's installed power plant capacity will need to be replaced by the construction of new facilities. The power plant investments required for this will be made in an environment marked by liberalisation and competition. This is the context of the present article, which analyses the causes behind the cyclical behaviour of power plant investment and identifies factors that influence it. Cycles in this connection are defined as recurring oscillations in power plant capacity and electricity prices. The authors also propose measures that could dampen the cyclical course of power plant investment over time. One of the major outcomes of the present model calculations is that the power production market, similarly to other capital-intensive branches of industry, is expected to experience strong price fluctuations in the future as well. As it has been framed up to now, the German electricity wholesale market will not be able to prevent the occurrence investment cycles in power plant construction. One way to counteract investment cycles would be to greatly expand the time horizon of the liquid spot market through greater activity on the part of trading firms. [German] In den naechsten 10 bis 15 Jahren sind in Deutschland und Europa sowie weltweit knapp die Haelfte der installierten Kraftwerksleistung zu ersetzen bzw. neu zu errichten. Die hierfuer erforderlichen Kraftwerksinvestitionen finden heute unter den veraenderten Rahmenbedingungen der Liberalisierung und des Wettbewerbs statt. In diesem Zusammenhang werden Ursachen von Zyklen bei Kraftwerksinvestitionen analysiert und deren Einflussfaktoren aufgezeigt. Zyklen werden als wiederkehrende Schwankungen der Kraftwerkskapazitaeten und Strompreise definiert. Zusaetzlich werden Massnahmen vorgeschlagen, die eine Zyklenbildung bei Kraftwerksinvestitionen abschwaechen koennen. Zunaechst erfolgt eine Untersuchung unter welchen Bedingungen

Einfluss physiologischer Faktoren auf die Gehstrecke und prognostische Aussagekraft des 6 Minuten Gehtestes bei Patienten mit dilatativer Kardiomyopathie und ihren Angehörigen

OpenAIRE

Temath, Christoph

2013-01-01

Ein Vergleich biometrischer Faktoren wie Alter, Geschlecht, BMI, Ejektionsfraktion, SF und linksventrikulärer enddistolischer Durchmesser, sowie dem NYHA Stadium bei Patienten mit dilatativer Kardiomyopathie und gesunden Probanden auf die während des 6-Minuten-Gehtest gelaufene Distanz ergab, dass Frauen mit dilatativer Kardiomyopathie eine kürzere Gehstrecke zurücklegen als Männer gleichen Alters und gleicher Erkrankung. Zudem la...

Magnetic resonance imaging in acute intractional tuberculosis; Magnetresonanztomographie bei akuter intrakranieller Tuberkulose

Energy Technology Data Exchange (ETDEWEB)

Venz, S. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Sander, B. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Benndorf, G. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Terstegge, K. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Podrabsky, P. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Cordes, M. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany); Felix, R. [Strahlenklinik und Poliklinik, Universitaetsklinikum Rudolf Virchow, Freie Univ. Berlin (Germany)

1994-12-31

We reported three cases of acute intracranial tuberculosis including miliary tuberculosis, basal meningitis, tuberculomas and neuritis of cranial nerves. All patients had native and contrast enhanced CT and MRI scans. MRI revealed more granulomas and a better imaging contrast in the detection of basal meningitis. Neuritis was diagnosed only with the MRI. MRI scans should be prefered as the imaging procedure in clinically presumed intracranial tuberculosis. (orig.) [Deutsch] Die Befunde von drei Patienten mit intrakranieller Tuberkulose (intrakranielle Miliartuberkulose, Meningitis tuberculosa, Neuritis und Tuberkulome) in der Magnetresonanztomographie (MRT) wurden mit der Computertomographie (CT) verglichen. Sowohl die MRT als auch die CT wurden nativ und nach Kontrastmittelgabe durchgefuehrt. Die MRT zeigte sich im Nachweis von Granulomen insbesondere im Bereich des Hirnstamms ueberlegen. Ebenso wurde ein hoeherer Bildkontrast bei der Darstellung der Meningitis beobachtet. Eine Neuritis der Hirnnerven war nur mit der MRT nachweisbar. Die kontrastmittelunterstuetzte MRT sollte in der bildgebenden Diagnostik einer intrakraniellen Turberkulose primaer zum Einsatz gelangen. (orig.)

Business combinations e consolidação das demonstrações contábeis: uma abordagem comparativa entre os pronunciamentos e normas dos US-GAAP, IASC e Brasil

Directory of Open Access Journals (Sweden)

Zaina Said El Hajj

2001-12-01

Full Text Available Este estudo apresenta uma abordagem comparativa entre os pronunciamentos e normas contábeis do IASB, US-GAAP e Brasil (BR-GAAP para as operações de business combinations (fusão, incorporação ou aquisição de controle e para a consolidação das demonstrações contábeis. Inicialmente, focaliza-se o tratamento contábil, contemplando-se os métodos de avaliação: pooling, que mantém os valores contábeis; e purchase, que modifica os valores contábeis das empresas fruto de business combination. Define-se business combinations de acordo com os conceitos contidos nos US-GAAP, IASB e nos pronunciamentos brasileiros para, em seguida, apresentar a definição adotada neste estudo. São destacadas algumas estatísticas das operações de business combinations e as principais dificuldades relacionadas ao tema, assim como a questão a ser investigada. Na análise comparativa, são tratados os principais pronunciamentos e normas contábeis emitidos, destacando-se as definições, o tratamento contábil, os métodos de avaliação, a consolidação e as evidenciações exigidas. O estudo inclui uma análise dos mais significativos procedimentos de consolidação e as evidenciações exigidas. Finalmente, são esclarecidas as principais similaridades e diferenças abordadas e as constatações do estudo.This study presents a comparative analysis among the IASB, US-GAAP and Brazilian (BR-GAAP accounting pronouncements for the transactions of business combinations (consolidation, merger or control acquisition and for the consolidation of financial statements. Initially, it focalizes the accounting treatment and contemplates the methods of evaluation: pooling, that carry on the book values; and purchase, that modify the book values of remaining entities of business combination. It reviews the definition of business combinations according to the concepts of IASB, US-GAAP and Brazilian pronouncements and, subsequently, the definition used in this study

[Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu] / Ago Künnap

Index Scriptorium Estoniae

Künnap, Ago, 1941-

2010-01-01

Arvustus: Gao Jingyi. Han yu yu bei Ou yu yan : Han yu yu Wula'er yu yan ji Yin Ou yu yan tong yuan tan jiu = Chinese language and languages of northern Europe. Beijing : Zhongguo she hui ke xue chu ban she, 2008

Bariumexaminations of the small intestine and the colon in inflammatory bowel disease; Konventionelle Duenn- und Dickdarmdiagnostik bei entzuendlichen Darmerkrankungen

Energy Technology Data Exchange (ETDEWEB)

Antes, G. [Abteilung fuer Radiologie, Klinikum Kempten-Oberallgaeu g, GmbH, Kempten (Germany)

2003-01-01

This article gives an overview of the possibilities of conventional radiography in the diagnosis of inflammatory bowel disease of the small intestine and colon.Material and methods For more than 25 years we examine the small bowel employing enteroclysis with barium and methylcellulose and the colon with the usual double-contrast method. In the last 152 months 1560 small bowel enemas were performed. In the last 40 months 410 examinations of the colon were performed. There is a thirty percent decrease in enteroclysis examinations within the past 5 years,however, the rate of examinations with positive results increased from 46 to 57%.The proportion of the inflammatory small intestinal diseases (not only Crohn's disease) remained constant with 18%.Concerning the examinations of the colon for inflammatory disease we confirmed the diagnosis in seven cases.The radiation exposure for the enteroclysis in inflammatory diseases was 7mSv, for colon examinations 14 mSv. Barium examinations, especially of the stomach and colon are decreasing in frequency.Therefore the art of performance and interpretation might get lost.Enteroclysis, however, is still the method of reference for the other imaging methods.The advantages compared to the other imaging methods are the excellent presentation of the details of the mucosal surface and the observation of functional disorders. (orig.) [German] Zielsetzung Diese Uebersichtsarbeit soll die Moeglichkeiten der konventionellen Roentgendiagnostik an Duenndarm und Kolon bei entzuendlichen Darmerkrankungen aufzeigen.Material und Methoden Seit mehr als 25 Jahren untersuchen wir den Duenndarm mit dem Enteroklysma mit Barium und Methylzellulose und das Kolon mit der ueblichen Doppelkontrastmethode. In den letzten 152 Monaten wurden 1560 Duenndarmuntersuchungen durchgefuehrt. In den letzten 40 Monaten erfolgten 410 Kolonuntersuchungen.Ergebnisse Bei den Duenndarmuntersuchungen wurde in den letzten 5 Jahren ein Rueckgang um 30% beobachtet

Applanationstonometrie zur nichtinvasiven kontinuierlichen Blutdruckmessung:Vergleich mit der Fingerlichtplethysmographie bei der Kipptisch-Orthostase Testung und Anwendbarkeit für die ergometrische Blutdruckmessung

OpenAIRE

Lammers, D. (Dirk)

2005-01-01

Die Applanationstonometrie wird mit der Fingerlichtplethysmographie während der Kipptisch-Testung verglichen und die Nutzbarkeit für die Ergometrie geprüft. 31 Patienten wurden einem Kipptisch Orthostase Test unterzogen. Der Patient erhielt kontinuierliches Blutdruckmonitoring durch Colin CBM 7000 am einen und Ohmeda Finapres am anderen Arm. Gleichzeitig wurden Referenzmessungen mittels Oszillometrie durchgeführt. Bei 22 weiteren Patienten wurden Belastungs-EKG’s durchgeführt. Die applanatio...

Gebrauch von Komplementärmedizin bei Patienten mit metastasierendem Melanom unter Therapie mit Ipilimumab innerhalb einer klinischen Studie.

Science.gov (United States)

Huebner, Jutta; Mohr, Peter; Simon, Jan-Christoph; Fluck, Michael; Berking, Carola; Zimmer, Lisa; Loquai, Carmen

2016-05-01

In Deutschland wenden 40-90 % aller Krebspatienten Methoden der komplementären and alternativen Medizin (KAM) an. Bis dato gibt es kein Datenmaterial zum Einsatz der KAM bei Melanompatienten. Das Ziel unserer Studie war es, Daten über den Gebrauch, die Informationsquellen und Ziele von Patienten mit metastasierendem Melanom zu erfassen. Einhundertsechsundfünfzig Patienten aus 25 Studienzentren nahmen an der DecOG-MM-PAL Multibasket Studie teil. Die beteiligten Personen wurden auch gebeten, an einer Nebenstudie teilzunehmen, die ihren Gebrauch von KAM erfassen sollte. Dazu wurde während der Behandlung ein standardisierter Fragebogen zu genau festgelegten Zeitpunkten ausgeteilt. Insgesamt gingen 55 Fragebögen von 32 (21 %) Melanompatienten ein. Von diesen gaben 17 (53 %) ein Interesse an KAM an, und sieben (22 %) machten von KAM Gebrauch. Die Hauptinformationsquellen (31 %) waren Familienmitglieder und Freunde, gefolgt von Ärzten (19 %). Die Hauptgründe für die Anwendung von KAM waren die Stärkung des Immunsystems (41 %) und des Körpers (34 %). Nahrungsergänzungsmittel (Vitamine und Spurenelemente) wurden am häufigsten angewendet (28 %). Eine relativ hohe Anzahl an Patienten mit metastasierendem Melanom machte trotz Teilnahme an einer klinischen Studie von KAM Gebrauch. Wechselwirkungen könnten durch biologisch basierte KAM auftreten, und hier besonders bei immunmodulierenden KAM- Strategien. Um Risiken zu vermeiden, sollte die Kommunikation zwischen den Ärzten und den Patienten verbessert werden. © 2016 Deutsche Dermatologische Gesellschaft (DDG). Published by John Wiley & Sons Ltd.

The involvement of splenic artery in the blood supply of hepatomas: its DSA findings and interventional treatment

International Nuclear Information System (INIS)

Duan Xuhua; Liang Huiming; Feng Gansheng; Zheng Chuangsheng; Ren Jianzhuang

2009-01-01

Objective: To investigate the DSA manifestations of the involvement of splenic artery in supplying blood to hepatomas and to assess the therapeutic value of super-selective interventional embolization. Methods: During the period of March 2005-June 2008, 897 patients with hepatoma underwent angiography and the involvement of splenic artery in the blood supply of hepatoma was confirmed in 7 cases. Splenic arteriography was performed by means of super-selective catheterization with 5 F Yashiro catheter together with 3 F SP catheter. The splenic arteries which supplied blood to hepatomas were embolized with hyper-liquid iodized-oil emulsion mixed with chemotherapy drug, which was followed by the injection of sufficient gelatin sponge or ethanol. The clinical results were analyzed. Results: Splenic arteriography revealed that the splenic artery was the main supplying vessel of the hepatoma in two cases, and was not the main supplying vessel of the hepatoma in five cases. The splenic supplying vessels were completely embolized in all 7 cases. After the procedure, AFP level was decreased over 50%, and in two patients it dropped to normal. CT checkup 4-6 weeks after the surgery revealed that the diameter of tumor decreased to 2.5 - 4.6 cm. Conclusion: The involvement of splenic artery in supplying blood to hepatomas is not common. Super-selective catheterization and sufficient embolization of the splenic supplying vessels are very important for improving the interventional effectiveness. (authors)

Clinical value of MRI concerning dissection of the supraaortic vessels; Wertigkeit der MRT bei posttraumatischer Dissektion supraaortaler Gefaesse

Energy Technology Data Exchange (ETDEWEB)

Pauls, S.; Goerich, J.; Kraemer, S. [Abt. fuer Diagnostische Radiologie, Univ. Ulm (Germany); Hartwig, E. [Unfall- und Wiederherstellungschirurgie, Univ. Ulm (Germany)

2002-03-01

Angiographien erstellt. Die Befundung der Schnittbilder erfolgte durch zwei erfahrene Radiologen im Konsens. Ergebnisse: Es fanden sich 7 Patienten (4,7%) mit insgesamt 9 posttraumatischen Dissektionen der A. vertebralis und/oder A. carotis interna; zur Diagnosestellung fuehrten folgende Schnittbilder: TOF-Sequenzen, kontrastgestuetzte MR-Angiographie, transversale T{sub 1}- und T{sub 2}-gewichtete Sequenzen sowie T{sub 1}-Sequenzen nach Kontrastmittelgabe. Hierdurch aenderte sich bei 4 Patienten das Therapieregime und es wurde eine Antikoagulation eingeleitet. Schlussfolgerungen: Bei zervikalen Verletzungen sollte bei allen Patienten eine MRT einschliesslich Angiographie- und T{sub 1}-Sequenzen mit und ohne KM durchgefuehrt werden, um eine Gefaessdissektion sicher zu diagnostizieren und die Ausdehnung praezise beurteilen zu koennen. Die MRT erwies sich in unserem Patientengut als hervorragendes diagnostisches Verfahren. (orig.)

Einsatz von E-Portfolios bei der Qualifizierung pädagogischer Professionals in restriktiven Settings

Directory of Open Access Journals (Sweden)

Dirk Jahn

2010-05-01

Full Text Available Der Beitrag zeigt den Einsatz von E-Portfolios bei der Qualifizierung pädagogischer Professionals in der beruflichen Bildung auf. Dabei werden als Referenz die Theorie der Selbstreflexion, des kritischen Denkens sowie des Konzeptwandels zugrunde gelegt. Es werden Möglichkeiten aufgezeigt, wie E-Portfolios auch in restriktiven Settings eingesetzt werden können. Bislang dominiert in der Literatur der Einsatz von E-Portfolios in der Schule bzw. in der Bildung von Lehrkräften. Restriktive Settings sind Settings, die für das formale Lernen nur kurze Zeiträume eröffnen, mit heterogenen Zielgruppen verbunden sind und die zum Teil ungünstige motivationale und kognitive Ausgangsvoraussetzungen mitbringen. Die dargestellten Ergebnisse fussen auf der Entwicklung, Erprobung und Erforschung eines solchen Settings, nämlich der Erprobung eines Qualifizierungskonzepts für pädagogische Professionals im Einzelhandel.

Presença do Gênero Feminino entre os Discentes dos Programas de Pós-Graduação de Ciências Contábeis no Brasil

Directory of Open Access Journals (Sweden)

Daniele Cristina Bernd

2017-01-01

Full Text Available Objetivo: apesar de existirem movimentos em direção à igualdade de gêneros quanto ao acesso à educação e às oportunidades no mercado de trabalho, a escassa presença da mulher em profissões que no passado eram, predominantemente, masculinas ainda pode persistir. Assim, este estudo objetiva verificar a presença do gênero feminino entre os discentes dos programas de pós-graduação em Ciências Contábeis do Brasil, no período de 2010 a 2016. Método: na Plataforma Sucupira, foram selecionados os 26 cursos de mestrado acadêmico, os 5 de mestrado profissional e os 13 de doutorado em Ciências Contábeis credenciados pela Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES, e com dados disponíveis para a pesquisa até 2016. Nesses, identificou-se um total de 3.013 discentes ingressantes, 2.058 de mestrado acadêmico, 530 de mestrado profissional e 451 de doutorado. Resultados: os resultados da pesquisa indicam que o número de discentes do gênero feminino ingressantes nos programas de pós-graduação em Ciências Contábeis no Brasil são inferiores ao de discentes do gênero masculino, no período analisado, com visíveis diferenças regionais. Contribuições: conclui-se que a presença do gênero feminino entre os discentes dos programas pesquisados tem evoluído, mas ainda há um longo caminho a ser percorrido para alcançar a igualdade de gêneros, o que é especialmente relevante se for considerado que isso pode se refletir em posteriores oportunidades de trabalho, uma lacuna de pesquisa a ser investigada.

[Postoperative adjuvante Therapie mit einem Mistelextrakt (Viscum album ssp. album) bei Hündinnen mit Mammatumoren].

Science.gov (United States)

Biegel, Ulrike; Stratmann, Nina; Knauf, Yvonne; Ruess, Katja; Reif, Marcus; Wehrend, Axel

2017-01-01

Hintergrund: Canine Mammatumoren (CMT) sind wegen ihrer Häufigkeit und hohen Malignitätsrate eine Herausforderung für die Veterinärmedizin. Bisher ist noch keine postoperative adjuvante Therapie als wirksamer Standard etabliert und in den nächsten Jahren wohl auch nicht zu erwarten. Zusätzlich ist die Frage nach der Verträglichkeit einer adjuvanten Therapie mit Erhaltung oder Verbesserung der Lebensqualität (LQ) wichtig. Die Therapie mit Mistelextrakten (Viscum album L.; VAE) ist in der Humanonkologie nach adjuvanter Tumorbasistherapie (Chemotherapie und Bestrahlung) eine sehr häufig verwendete, zusätzliche adjuvante Behandlungsmethode. Auch bei verschiedenen Tierarten werden inzwischen Mistelpräparate in der Onkologie erfolgreich angewendet. Methoden: Überprüfung von Wirkung und Nutzen einer postoperativen, adjuvanten Misteltherapie beim CMT sowie Erfassung der LQ unter der VAE-Behandlung. Ausgewertet wurden 56 Hündinnen mit Mammaadenokarzinom, 33 ausschließlich operierte Kontrolltiere und 23 operierte Tiere, die adjuvant VAE erhielten. Ergebnisse: Die mediane Überlebenszeit (MST) aller Tiere (n = 56) betrug 32 Monate (Interquartilbereich 13-51 Monate). Im deskriptiven Vergleich der Überlebenszeiten (ST) nach Kaplan-Meier waren nach 12, 24, 36 bzw. 48 Monaten noch 24, 20, 15 bzw. 5 Hündinnen (entsprechend 72,7%, 60,6%, 45,1%, 12,4%) der Kontrollgruppe sowie 19, 14, 11 und 1 Hündin (82,6%, 60,9%, 47,8%, 4,3%) der VAE-Gruppe am Leben. Die VAE-Therapie führte zu einem geringeren Gesamtversterberisiko, das statistisch nicht signifikant war (Hazard Ratio (HR) 0,530, 95%-Konfidenzintervall (KI) 0,222-1,262; p = 0,15). Tendenziell (p = 0,07) zeigte sich eine Verringerung des tumorbedingten Sterberisikos auf 25% (HR 0,251, 95%-KI 0,056-1,122). Schlussfolgerungen: Es kann eine Tendenz zur Senkung des tumorbedingten Sterberisikos der VAE-Gruppe bei guter Verträglichkeit der Therapie angenommen werden. Die LQ der Tiere blieb über die gesamte

Contabilidade pública: a evidenciação em notas explicativas das informações contábeis provenientes do reconhecimento dos bens de uso comum nos municípios da região metropolitana de São Paulo

OpenAIRE

Seraphim, Paulo Rogerio

2011-01-01

A Contabilidade Pública Brasileira está a caminho da convergência as Normas Internacionais de Contabilidade. Este trabalho abordou o estudo da evidenciação das informações contábeis oriundas do reconhecimento dos bens de uso comum como pontes, ruas, estradas, viadutos e praças pela Administração Pública através das notas explicativas. O objetivo geral foi validar uma proposta de estrutura de nota explicativa que promova a evidenciação das informações contábeis a seus usuários, em apoio ao pro...

Contribution of BeiDou satellite system for long baseline GNSS measurement in Indonesia

Science.gov (United States)

Gumilar, I.; Bramanto, B.; Kuntjoro, W.; Abidin, H. Z.; Trihantoro, N. F.

2018-05-01

The demand for more precise positioning method using GNSS (Global Navigation Satellite System) in Indonesia continue to rise. The accuracy of GNSS positioning depends on the length of baseline and the distribution of observed satellites. BeiDou Navigation Satellite System (BDS) is a positioning system owned by China that operating in Asia-Pacific region, including Indonesia. This research aims to find out the contribution of BDS in increasing the accuracy of long baseline static positioning in Indonesia. The contributions are assessed by comparing the accuracy of measurement using only GPS (Global Positioning System) and measurement using the combination of GPS and BDS. The data used is 5 days of GPS and BDS measurement data for baseline with 120 km in length. The software used is open-source RTKLIB and commercial software Compass Solution. This research will explain in detail the contribution of BDS to the accuracy of position in long baseline static GNSS measurement.

COMPORTAMENTO DOS DEZ MAIORES BANCOS BRASILEIROS DURANTE A CRISE DO SUBPRIME: UMA ANÁLISE POR MEIO DE INDICADORES CONTÁBEIS

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Rosane Maria Pio da Silva

Full Text Available O presente artigo tem por objetivo demonstrar o comportamento dos dez maiores bancos brasileiros no período de junho de 2008 a de setembro de 2009, a partir da análise de indicadores contábeis. Para tanto, foram calculados 16 índices com periodicidade trimestral, extraídos a partir das informações contidas nos relatórios contábeis, caracterizando a pesquisa como documental. Os índices foram separados em cinco categorias: liquidez, capital, rentabilidade, receita e mercado. Os resultados obtidos apontaram que a maioria das instituições financeiras da amostra teve capacidade de gerir seus recursos de forma a obter condições de manter o crédito inicialmente, para então, a partir do primeiro trimestre de 2009, impulsionada pelos bancos públicos, elevar suas operações de crédito. Além disso, a maioria dos bancos apresentou uma tendência anticíclica de fomentar as atividades produtivas, com preferência às atividades de maior liquidez em detrimento da rentabilidade, tendo dessa forma uma postura mais conservadora. Por fim, verificou-se que as iniciativas adotadas pelo governo, o equilíbrio econômico brasileiro e os recursos oferecidos pelos bancos ajudaram a produzir um ambiente para o reaquecimento das atividades empresariais durante o período mais agudo da crise do subprime.

Guidelines for MIBG-scintigraphy in children; Empfehlungen zur Durchfuehrung der MIBG-Szintigraphie bei Kindern. Leitlinie uebernommen vom Paediatric Committee der European Association of Nuclear Medicine (EANM)

Energy Technology Data Exchange (ETDEWEB)

Olivier, P. [CHU Nancy (France); Colarinha, P. [Inst. Portugues de Oncologia, Lisbon (Portugal); Fettich, J. [Univ. Medical Centre Ljubljana (Slovenia); Fischer, S.; Hahn, K.; Porn, U. [Klinik fuer Nuklearmedizin, Univ. of Munich (Germany); Froekier, J. [Aarhus Univ. Hospital - Skejby (Denmark); Giammarile, F. [Centre Leon Berard, Lyon (France); Gordon, I. [Great Ormond Street Hospital for Children, London (United Kingdom); Kabasakal, L. [Cerraphasa Tipp Fakultesi, Nukleer Tipp Ana Bilim Dali, Aksaray (Turkey); Mann, M. [Red Cross Hospital Cape Town (South Africa); Mitjavila, M. [Hospital Universitario de Getafe, Madrid (Spain); Piepsz, A. [AZ VUB and CHU St Pierre, Brussels (Belgium); Sixt, R. [Sahlgrenska Univ. Hospital Oestra, Goeteborg (Sweden); Velzen, J. van [ARPES (Netherlands)

2002-07-01

These ''Empfehlungen'' are the german translation of the Guidelines on MIBG-Scintigraphy in Children, which were published by the Paediatric Committee of the European Association of Nuclear Medicine. (orig.) [German] Bei den vorliegenden Empfehlungen handelt es sich um die deutsche Uebersetzung der vom Paediatric Committee der European Association of Nuclear Medicine (EANM) publizierten Guidelines. (orig.)

Guidelines for direct radionuclide cystography; Empfehlungen zur Durchfuehrung der direkten Radionuklid-Zystographie bei Kindern. Richtlinie uebernommen vom Paediatric Committee der European Association of Nuclear Medicine (EANM)

Energy Technology Data Exchange (ETDEWEB)

Fettich, J. [Univ. Medical Centre Ljubljana (Slovenia); Colarinha, P. [Inst. Portugues de Oncologia, Lisboa (Portugal); Fischer, S.; Hahn, K.; Porn, U. [Klinik fuer Nuklearmedizin, LMU Muenchen (Germany); Froekier, J. [Aarhus Univ. Hospital - Skejby (Denmark); Gordon, I. [Great Ormond Street Hospital for Children, London (United Kingdom); Kabasakal, L. [Cerraphasa Tip Fakultesi, Nukleer Tip Ana Bilim Dali, Aksaray (Turkey); Mann, M. [Inst. of Child Health, Rondebosh, Red Cross Hospital, Capetown (South Africa); Mitjavila, M. [Hospital Universitario de Getafe, Madrid (Spain); Olivier, P. [CHU Nancy (France); Piepsz, A. [CHU St Pierre (Belgium); Roca, I. [Hospital Vall d' Hebron, Barcelona (Spain); Sixt, R. [The Queen Silvia Children' s Hospital, Goeteborg (Sweden); Velzen, J. van [ARPES (Netherlands)

2002-07-01

These ''Empfehlungen'' are the german translation of the Guidelines on MIBG-Scintigraphy in Children, which were published by the Paediatric Committee of the European Association of Nuclear Medicine. (orig.) [German] Bei den vorliegenden Empfehlungen handelt es sich um die deutsche Uebersetzung der vom Paediatric Committee der European Association of Nuclear Medicine (EANM) publizierten Guidelines. (orig.)

UTILIZAÇÃO DOS INDICADORES CONTÁBEIS NO PROCESSO DE AVALIAÇÃO DE EMPRESAS: A PERCEPÇÃO DE PROFESSORES DE CONTABILIDADE E DE ANALISTAS DE INVESTIMENTO

Directory of Open Access Journals (Sweden)

Glauber de Castro Barbosa

2014-12-01

Full Text Available A Contabilidade tem como uma de suas funções subsidiar o processo de Avaliação de Empresas e o pode fazê-lo por intermédio de indicadores contábeis. Dessa maneira, o presente trabalho teve o objetivo de testar por meio de um questionário se esses indicadores realmente são relevantes no processo de avaliação. O questionário foi encaminhado a Professores do curso de Ciências Contábeis e para Analistas de Investimento. Houve 174 respondentes, sendo a maior parte de professores (79%. Constatou-se que a Contabilidade é tida como importante no processo de avaliação para ambos os grupos, com destaque à Demonstração do Resultado do Exercício (DRE, a Demonstração dos Fluxos de Caixa (DFC e ao Balanço Patrimonial, que foram considerados, nessa ordem, os demonstrativos mais importantes no processo de avaliação. Da mesma forma, os 24 indicadores contábeis analisados também foram bem avaliados, sendo que o pior avaliado foi o Índice de Liquidez Imediata (média de 6,4971 em uma escala de 0 a 10 e o que foi tido como mais importante foi o Retorno Sobre o Patrimônio Líquido (ROE, com média 8,6244. Não foram observadas diferenças nos padrões de respostas entre Analistas de Investimento e professores; no entanto, a titulação foi uma variável relevante na respostas.

Medical-oncological aspects in the treatment of pancreatic cancer; Internistisch-onkologische Aspekte bei der Behandlung des Pankreaskarzinoms

Energy Technology Data Exchange (ETDEWEB)

Heinemann, V. [Klinikum Grosshadern, Ludwig-Maximilians-Universitaet Muenchen (Germany). Medizinische Klinik und Poliklinik III

2009-02-15

Pancreatic cancer is a highly malignant disease and despite progress in systemic therapy survival is still short. For patients with R0/R1 resected disease, adjuvant chemotherapy with gemcitabine has been established as the standard treatment. More controversy exists with regard to optimal treatment of locally advanced non-metastatic pancreatic cancer. However, there is evidence to suggest that patients who respond to an initial phase of chemotherapy may be those who benefit most from sequential chemoradiotherapy. Specifically, in the treatment of advanced and metastatic disease chemotherapy or radiotherapy cannot stand alone but must be accompanied by multidisciplinary treatment approaches involving pain management, weight control, psychooncological care and palliative care. Monotherapy with gemcitabine and the combined use of gemcitabine with erlotinib are established standards for treatment of metastatic pancreatic cancer. Patients in a good general condition but where the gemcitabine-based therapy failed should be offered second-line treatment. (orig.) [German] Das Pankreaskarzinom ist eine hochmaligne Erkrankung, die trotz nachweisbarer klinischer Fortschritte weiterhin mit einem meist kurzen Ueberleben verbunden ist. Bei R0/R1-resezierten Patienten gilt eine adjuvante Behandlung mit Gemcitabin gegenwaertig als etablierter Behandlungsstandard. Weniger eindeutig ist die optimale Therapie des lokal fortgeschrittenen, nichtmetastasierten Pankreaskarzinoms (LAPC). Es gibt aber Hinweise dafuer, dass Patienten, die auf eine initiale Chemotherapiephase ansprachen, von einer nachgeschalteten Radiochemotherapie profitieren koennen. Gerade zur Behandlung des metastasierten Pankreaskarzinoms sollten die Chemo- oder die Radiochemotherapie nicht allein stehen, sondern durch multidisziplinaere Behandlungsansaetze unterstuetzt werden. Dazu gehoeren die Schmerz- und Ernaehrungstherapie, Psychoonkologie und Palliativmedizin. Bei der Behandlung des metastasierten

Follow-up after embolization of ruptured intracranial aneurysms: A prospective comparison of two-dimensional digital subtraction angiography, three-dimensional digital subtraction angiography, and time-of-flight magnetic resonance angiography

International Nuclear Information System (INIS)

Serafin, Zbigniew; Strzesniewski, Piotr; Lasek, Wladyslaw; Beuth, Wojciech

2012-01-01

To prospectively compare of the diagnostic value of digital subtraction angiography (DSA) and time-of-flight magnetic resonance angiography (TOF-MRA) in the follow-up of intracranial aneurysms after endovascular treatment. Seventy-two consecutive patients were examined 3 months after the embolization. The index tests included: two-dimensional DSA (2D-DSA), three-dimensional DSA (3D-DSA), and TOF-MRA. The reference test was a retrospective consensus between 2D-DSA images, 3D-DSA images, and source rotational DSA images. The evaluation included: detection of the residual flow, quantification of the flow, and validity of the decision regarding retreatment. Intraobserver agreement and interobserver agreement were determined. The sensitivity and specificity of residual flow detection ranged from 84.6 % (2D-DSA and TOF-MRA) to 92.3 % (3D-DSA) and from 91.3 % (TOF-MRA) to 97.8 % (3D-DSA), respectively. The accuracy of occlusion degree evaluation ranged from 0.78 (2D-DSA) to 0.92 (3D-DSA, Cohen's kappa). The 2D-DSA method presented lower performance in the decision on retreatment than 3D-DSA (P < 0.05, ROC analysis). The intraobserver agreement was very good for all techniques (κ = 0.80-0.97). The interobserver agreement was moderate for TOF-MRA and very good for 2D-DSA and 3D-DSA (κ = 0.72-0.94). Considering the invasiveness of DSA and the minor difference in the diagnostic performance between 3D-DSA and TOF-MRA, the latter method should be the first-line modality for follow-up after aneurysm embolization. (orig.)

La Lavagna Interattiva Multimediale a supporto degli studenti disabili e con DSA all’Università di Modena e Reggio Emilia

Directory of Open Access Journals (Sweden)

Giacomo Guaraldi

2013-03-01

Full Text Available Negli ultimi anni l’introduzione delle moderne tecnologie ha consentito agli studenti con disabilità di raggiungere un maggior grado di autonomia e ha favorito un mutamento nella didattica che è diventata sempre più una «didattica inclusiva», incentrata sui bisogni educativi speciali di tali soggetti e soprattutto sulle potenzialità nascoste in essi. I software per l’apprendimento, le sintesi vocali, le lavagne interattive multimediali (LIM, i netbook, i tablets, gli Ipad creano una «rete integrata» che permette, grazie a linguaggi diversi e multimodali, di accrescere l’autostima dei soggetti con disabilità e favorire la loro autonomia. La lavagna è uno strumento che stimola l’apprendimento, in quanto utilizza un linguaggio più vicino alla modalità comunicativa delle nuove generazioni, riducendo così la distanza docente e discente. Questo è tanto più importante nel caso di studenti con disabilità o con disturbo specifico dell’apprendimento: il disabile sensoriale può utilizzare la modalità comunicativa residua, il disabile motorio può «sfogliare» un testo, farselo leggere, prendere appunti, il ragazzo con DSA può usufruire della sintesi vocale per la lettura e/o per il supporto alla scrittura.

Precise positioning with current multi-constellation Global Navigation Satellite Systems: GPS, GLONASS, Galileo and BeiDou.

Science.gov (United States)

Li, Xingxing; Zhang, Xiaohong; Ren, Xiaodong; Fritsche, Mathias; Wickert, Jens; Schuh, Harald

2015-02-09

The world of satellite navigation is undergoing dramatic changes with the rapid development of multi-constellation Global Navigation Satellite Systems (GNSSs). At the moment more than 70 satellites are already in view, and about 120 satellites will be available once all four systems (BeiDou + Galileo + GLONASS + GPS) are fully deployed in the next few years. This will bring great opportunities and challenges for both scientific and engineering applications. In this paper we develop a four-system positioning model to make full use of all available observations from different GNSSs. The significant improvement of satellite visibility, spatial geometry, dilution of precision, convergence, accuracy, continuity and reliability that a combining utilization of multi-GNSS brings to precise positioning are carefully analyzed and evaluated, especially in constrained environments.

Uma Análise Crítica Entre os Currículos dos Cursos de Ciências Contábeis nos Países do Mercosul e o Proposto Pela ONU/UNCTAD/ISAR

Directory of Open Access Journals (Sweden)

Giovanna Tonetto Segantini

2013-07-01

Full Text Available A harmonização das normas contábeis tornou-se uma necessidade dos usuários externos e internos da informação contábil, uma vez que passaram a atuar em diversos mercados e a prestar contas aos usuários com necessidades variadas, pois o mercado cada vez mais globalizado exige profissionais preparados para atuar dentro e fora do seu país. Visando isso, a ONU/UNCTAD/ISAR desenvolveu um Currículo Mundial para servir de referência para os cursos de Ciências Contábeis, buscando prover conhecimentos internacionais de normas contábeis independentemente do país responsável pela formação do profissional. Assim, o objetivo geral do artigo foi analisar e comparar a adequação dos currículos dos cursos de ciências contábeis de quatro universidades do MERCOSUL, sendo uma de cada país, com o currículo proposto pela ONU/UNCTAD/ISAR. As universidades selecionadas foram: Facultad de Ciencias Econômicas de la Universidad de Buenos Aires (Argentina; Faculdade de Economia, Administração e Contabilidade da Universidade de São Paulo (Brasil; Universidad Nacional de Asunción (Paraguai; e Facultad de Ciências Econômicas y de Administración de la Universidad de la República (Uruguai, e suas matrizes curriculares foram comparadas com o Currículo Mundial proposto pela ONU/UNCTAD/ISAR. Os resultados indicam que a similaridade entre os currículos das quatro universidades selecionadas com o proposto pela ONU/UNCTAD/ISAR é alta, existindo, em média, 76,71% de semelhança entre as matérias dos currículos. Por ser apenas uma recomendação, as universidades pesquisadas demonstraram possuir certa flexibilidade na elaboração de seus currículos.

Sacroiliitis in children with spondyloarthropathy: therapeutic effect of CT-guided intra-articular corticosteroid injection; Sakroiliitis bei Kinder mit Spondylarthropathie: Therapeutischer Effekt der CT-gestuetzten intraartikulaeren Kortikosteroid-Injektionen

Energy Technology Data Exchange (ETDEWEB)

Fischer, T.; Hermann, K.G.A.; Diekmann, F.; Hamm, B. [Humboldt-Universitaet, Berlin (Germany). Universitaetsklinikum Charite, Inst. fuer Radiologie; Biedermann, T. [HELIOS Klinikum Berlin (Germany). II. Klinik fuer Kinderheilkunde und Jugendmedizin, Abt. Kinderrheumatologie; Braun, J. [Rheumazentrum Ruhrgebiet, St. Josefs-Krankenhaus (Germany); Bollow, M. [Augusta-Krankenhaus, Bochum (Germany). Inst. fuer Radiologie

2003-06-01

. The follow-up dynamic MRI (0.1 mmol/kg body weight) during therapy showed a statistically significant lower contrast-enhancement in both groups (group 1: 117{+-}43% versus 38{+-}24%, p<0.05; group 2: 127{+-}59% versus 38{+-}22%, p<0.05). One third of the patients of group 2 showed progression of joint destruction despite absence of subjective complaints. (orig.) [German] Ziel: Prospektive Pruefung des therapeutischen Effektes der CT-gesteuerten intraartikulaeren Kortikosteroid-Injektion entzuendlicher Sakroiliakalgelenke (SIG) bei Kindern mit juveniler Spondylarthropathie (jSpA) im Vergleich zur konventionellen Therapie mit nichtsteroidalen Antirheumatika (NSAR) sowie Bestimmung der Wertigkeit der Magnetresonanztomographie (MRT) bei der Indikationsstellung und der Therapieverlaufskontrolle. Material und Methode: Bei 89 Kindern mit bekannter jSpA wurden mittels dynamischer MRT uni- oder bilaterale Sakroiliitiden diagnostiziert. Bei allen 89 Patienten wurde daraufhin eine Therapie mit NSAR eingeleitet bzw. bereits bestehende Therapien fortgesetzt. Vier Wochen nach der diagnostischen MRT wurden zwei Gruppen definiert: 33 Patienten mit klinischem Response auf NSAR (Gruppe 1) und 56 Nonresponder (Gruppe 2). Die Patienten der Gruppe 2 wurden unter Belassung der NSAR zusaetzlich einer CT-gestuetzten (Low-Dose-Technik) intraartikulaeren Kortikosteroid-Injektion zugefuehrt, wobei insgesamt 83 SIG punktiert und infiltriert wurden (27 bilateral, 29 unilateral). Die Indikationsstellung zur Intervention beruhte auf der zuvor MR-tomographisch gesicherten Entzuendungsaktivitaet. Klinische Therapieverlaufskontrollen erfolgten in 8- bis 12-woechigen Intervallen ueber einen Zeitraum von 20 Monaten. MRT-Verlaufskontrollen wurden bei allen 56 Kindern der Gruppe 2 und bei 15 von 33 Kindern der Gruppe 1 in einem Zeitraum von 8{+-}4 Monaten nach der Erstuntersuchung durchgefuehrt. Ergebnisse: Ingesamt 87,5% der komplikationslos punktierten Kinder der Gruppe 2 (Standardtherapie

Informatividade dos lucros contábeis e divulgação dos ativos biológicos: evidências brasileiras

OpenAIRE

Holanda, Allan Pinheiro

2013-01-01

A pesquisa tem o objetivo de investigar a influência exercida pela divulgação dos ativos biológicos na informatividade dos lucros contábeis nas firmas brasileiras listadas na BM&FBovespa, considerando-se o período de 2010 a 2011. Para a investigação da informatividade dos ativos biológicos foi utilizada a adaptação dos modelos propostos por Easton e Harris (1991) e Francis e Schipper (1999). Os ativos biológicos, por sua vez, foram mensurados de duas maneiras, pela simples existência da c...

PENGUKURAN KINERJA KEUANGAN DENGAN METODE EAGLES (Studi Kasus Pada Bank BUMN Yang Listing Di BEI Tahun 2011 - 2013

Directory of Open Access Journals (Sweden)

Arif Hartono

2016-03-01

Full Text Available Kinerja keuangan bank biasanya diukur dengan indikator kecukupan modal, likuiditas dan profitabilitas bank. Penelitian ini menggunakan analisis EAGLES, untuk mengukur dan membandingkan kinerja bank secara lebih tepat, obyektif dan konsisten. Populasi yang digunakan adalah semua bank BUMN yang listing di BEI tahun 2011-2013. Hasil penelitian diketahui bahwa kinerja keuangan bank BUMN ditinjau dari rasio ROA (Return On Asset, Asset Quality, DGR (Deposite Growth Rate, CCR (Core Capital Ratio, SRQ by Out Interest, menunjukan nilai normal. Sedangkan bank BUMN ditinjau dari aspek, ROE (Return On Equity , LGR (loan growth rate, liquidity, CAR (capital adequacy ratio SRQ by Personalia, menunjukan kinerja keuangan yang kurang baik.

MR spectroscopy in metabolic disorders of the brain; MR-Spektroskopie bei Stoffwechselerkrankungen des Gehirns

Energy Technology Data Exchange (ETDEWEB)

Yilmaz, U. [Universitaetsklinikum des Saarlandes, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar (Germany)

2017-06-15

Metabolic disorders of the brain often present a particular challenge for the neuroradiologist, since the disorders are rare, changes on conventional MR are often non-specific and there are numerous differential diagnoses for the white substance lesions. As a complementary method to conventional brain MRI, MR spectroscopy may help to reduce the scope of the differential diagnosis. Entities with specific MR spectroscopy patterns are Canavan disease, maple syrup urine disease, nonketotic hyperglycinemia and creatine deficiency. (orig.) [German] Die Diagnostik metabolischer Erkrankungen des Gehirns stellt eine besondere Herausforderung in der Neuroradiologie dar, da die Erkrankungen insgesamt selten, die bildmorphologischen Befunde haeufig unspezifisch sind und es eine Vielzahl von Differenzialdiagnosen fuer die Veraenderungen der weissen Substanz gibt. Als zusaetzliche Technik kann die MR-Spektroskopie bei Stoffwechselerkrankungen helfen, die Diagnose einzugrenzen. Krankheitsentitaeten, die spezifische Veraenderungen in der Spektroskopie aufweisen, sind der Morbus Canavan, die Ahornsirupkrankheit, die nichtketotische Hyperglyzinaemie und Kreatinmangelsyndrome. (orig.)

Follow-up after embolization of ruptured intracranial aneurysms: a prospective comparison of two-dimensional digital subtraction angiography, three-dimensional digital subtraction angiography, and time-of-flight magnetic resonance angiography.

Science.gov (United States)

Serafin, Zbigniew; Strześniewski, Piotr; Lasek, Władysław; Beuth, Wojciech

2012-11-01

To prospectively compare of the diagnostic value of digital subtraction angiography (DSA) and time-of-flight magnetic resonance angiography (TOF-MRA) in the follow-up of intracranial aneurysms after endovascular treatment. Seventy-two consecutive patients were examined 3 months after the embolization. The index tests included: two-dimensional DSA (2D-DSA), three-dimensional DSA (3D-DSA), and TOF-MRA. The reference test was a retrospective consensus between 2D-DSA images, 3D-DSA images, and source rotational DSA images. The evaluation included: detection of the residual flow, quantification of the flow, and validity of the decision regarding retreatment. Intraobserver agreement and interobserver agreement were determined. The sensitivity and specificity of residual flow detection ranged from 84.6 % (2D-DSA and TOF-MRA) to 92.3 % (3D-DSA) and from 91.3 % (TOF-MRA) to 97.8 % (3D-DSA), respectively. The accuracy of occlusion degree evaluation ranged from 0.78 (2D-DSA) to 0.92 (3D-DSA, Cohen's kappa). The 2D-DSA method presented lower performance in the decision on retreatment than 3D-DSA (P < 0.05, ROC analysis). The intraobserver agreement was very good for all techniques (κ = 0.80-0.97). The interobserver agreement was moderate for TOF-MRA and very good for 2D-DSA and 3D-DSA (κ = 0.72-0.94). Considering the invasiveness of DSA and the minor difference in the diagnostic performance between 3D-DSA and TOF-MRA, the latter method should be the first-line modality for follow-up after aneurysm embolization.

Follow-up after embolization of ruptured intracranial aneurysms: A prospective comparison of two-dimensional digital subtraction angiography, three-dimensional digital subtraction angiography, and time-of-flight magnetic resonance angiography

Energy Technology Data Exchange (ETDEWEB)

Serafin, Zbigniew; Strzesniewski, Piotr; Lasek, Wladyslaw [Nicolaus Copernicus University, Collegium Medicum, Department of Radiology and Diagnostic Imaging, Bydgoszcz (Poland); Beuth, Wojciech [Nicolaus Copernicus University, Collegium Medicum, Department of Neurosurgery and Neurotraumatology, Bydgoszcz (Poland)

2012-11-15

To prospectively compare of the diagnostic value of digital subtraction angiography (DSA) and time-of-flight magnetic resonance angiography (TOF-MRA) in the follow-up of intracranial aneurysms after endovascular treatment. Seventy-two consecutive patients were examined 3 months after the embolization. The index tests included: two-dimensional DSA (2D-DSA), three-dimensional DSA (3D-DSA), and TOF-MRA. The reference test was a retrospective consensus between 2D-DSA images, 3D-DSA images, and source rotational DSA images. The evaluation included: detection of the residual flow, quantification of the flow, and validity of the decision regarding retreatment. Intraobserver agreement and interobserver agreement were determined. The sensitivity and specificity of residual flow detection ranged from 84.6 % (2D-DSA and TOF-MRA) to 92.3 % (3D-DSA) and from 91.3 % (TOF-MRA) to 97.8 % (3D-DSA), respectively. The accuracy of occlusion degree evaluation ranged from 0.78 (2D-DSA) to 0.92 (3D-DSA, Cohen's kappa). The 2D-DSA method presented lower performance in the decision on retreatment than 3D-DSA (P < 0.05, ROC analysis). The intraobserver agreement was very good for all techniques ({kappa} = 0.80-0.97). The interobserver agreement was moderate for TOF-MRA and very good for 2D-DSA and 3D-DSA ({kappa} = 0.72-0.94). Considering the invasiveness of DSA and the minor difference in the diagnostic performance between 3D-DSA and TOF-MRA, the latter method should be the first-line modality for follow-up after aneurysm embolization. (orig.)

Static-dynamic MR urography. Comparison with excretory urography and scintigraphy in experimentally induced urinary tract obstruction (UTO); Statisch-dynamische MR-Urographie. Vergleich mit Ausscheidungsurographie und Szintigraphie bei experimentell induzierter Harntransportstoerung (HTS)

Energy Technology Data Exchange (ETDEWEB)

Rohrschneider, W.K.; Wunsch, R.; Troeger, J. [Paediatrische Radiologie, Univ. Heidelberg (Germany); Hoffend, J. [Nuklearmedizinische Klinik, Univ. Heidelberg (Germany); Becker, K. [Inst. fuer Versuchstierkunde, Univ. Heidelberg (Germany); Darge, K.; Clorius, J.H. [Kooperationseinheit Nuklearmedizin, Deutsches Krebsforschungszentrum, Heidelberg (Germany); Kooijman, H. [Philips Medizin-Systeme, Hamburg (Germany)

2001-02-01

Purpose: To assess the diagnostic value of combined static-dynamic MR urography (MRU) for the functional-morphological evaluation of experimentally induced urinary tract obstruction. Methods: Static-dynamic MRU - combination study with a respiratory-triggered 3D-IR-TSE sequence and a dynamic 2D-FFE sequence after Gd-DTPA and furosemide - was obtained in comparison with {sup 99m}Tc-MAG3 diuretic renal scintigraphy (DRS), excretory urography (EU) and ultrasound (US) in 29 healthy piglets and in 20 piglets with surgically induced ureteric stenosis (total of 50 postoperative examination blocks). Results: MRU allowed complete depiction of the urinary tract in all controls, in operated piglets the stenosis was always correctly identified. Quality of MRU was superior to EU in 36 to 43 comparative studies. Calculation of single kidney function from parenchymal renograms, and assessment of urinary excretion from whole-kidney renograms resulted in a highly significant agreement of MRU with DRS. Conclusion: Static-dynamic MR urography allows excellent depiction of experimentally induced urinary tract obstruction, and reliable assessment of individual renal function and urinary excretion. Two advantages of the method stand out, it does not require radiation and it permits a functional-morphological correlation. (orig.) [German] Ziel: Einschaetzung der Wertigkeit der kombinierten statisch-dynamischen MR-Urographie (MRU) zur umfassenden funktionell-morphologischen Diagnostik tierexperimentell induzierter Harntransportstoerungen. Methodik: Die statisch-dynamische MRU-Kombination aus einer atemgetriggerten 3D-IR-TSE-Sequenz und einer dynamischen 2D-FFE-Sequenz nach Gd-DTPA und Furosemid - wurde im Vergleich zu {sup 99m}Tc-MAG3-Diurese-Nierenszintigraphie (DNS), Ultraschall (US) und Ausscheidungsurographie (AUG) bei 29 gesunden Ferkeln sowie bei 20 Ferkeln mit operativ indizierter Harnwegsstenose (insgesamt 50 postoperative Untersuchungsbloecke) durchgefuehrt. Ergebnisse: Die MRU

Radiochemotherapy with gemcitabine and cisplatin in pancreatic cancer - feasible and effective; Radiochemotherapie mit Gemcitabin und Cisplatin bei Pankreaskarzinom - durchfuehrbar und effektiv

Energy Technology Data Exchange (ETDEWEB)

Wilkowski, R.; Thoma, M.; Duehmke, E. [Klinik und Poliklinik fuer Strahlentherapie, Klinikum Grosshadern, Ludwig-Maximilians-Univ. Muenchen (Germany); Heinemann, V. [Medizinische Klinik III, Klinikum Grosshadern, Ludwig-Maximilians-Univ. Muenchen (Germany); Rau, H.G. [Abt. fuer Viszeralchirurgie, Klinikum Dachau (Germany); Wagner, A. [Medizinische Klinik II, Klinikum Grosshadern, Ludwig-Maximilians-Univ. Muenchen (Germany); Stoffregen, C. [Lilly Deutschland GmbH, Bad Homburg (Germany)

2003-02-01

sequential gemcitabine and cisplatin with radiation is feasible with justifiable side effects. To evaluate the promising remission and survival rates, randomized trials of neoadjuvant and primary chemoradiation are started. (orig.) [German] Hintergrund: Die simultane Radiochemotherapie unter Verwendung von Gemcitabin scheint bei der Behandlung des Pankreaskarzinoms ein hoffnungsvoller Ansatz, da Gemcitabin als Monosubstanz oder in Kombination mit anderen Zytostatika eine verbesserte Wirksamkeit beim (metastasierten) Pankreaskarzinom im Vergleich zu 5-FU-haltigen Therapieschemata zeigt und zudem strahlensensibilisierendes Potential besitzt. In der vorliegenden Arbeit werden die Pilotdaten einer sequentiellen und simultanen Radiochemotherapie unter Verwendung von Gemcitabin und Cisplatin vorgestellt. Patienten und Methode: 57 Patienten (w/m 23/34) mit Pankreaskarzinom wurden insgesamt behandelt, davon 33 Patienten mit inoperablem Tumor, 19 Patienten nach Tumorresektion (R1-Resektion und/oder pN+) sowie fuenf Patienten mit Lokalrezidiv. Die Strahlentherapie wurde in konventioneller Fraktionierung bis zu einer Dosis von 45,0 Gy im Referenzpunkt nach ICRU (50 Patienten 1,8 Gy ED) bzw. 50,0 Gy im Zielvolumen I. Ordnung (sieben Patienten, 45,0 Gy im ZV II. Ordnung, 1,8/2,0 Gy ED) durchgefuehrt. Simultan zur Bestrahlung wurden Cisplatin 30 mg/m{sup 2} und Gemcitabin 300 mg/m{sup 2} an den Tagen 1, 8, 22 und 29 verabreicht. Nach Abschluss der simultanen Radiochemotherapie wurden sequentiell zwei Zyklen Gemcitabin/Cisplatin (1000 mg/m{sup 2}/50 mg/m{sup 2} d 1, 15) verabreicht. Ergebnisse: Bei einer medianen Nachbeobachtungszeit von 8,2 Monaten betraegt die aktuelle mediane Ueberlebenszeit 14,8 Monate (inoperable Patienten 10,3 Monate, postoperative Patienten 15,1 Monate). Bei 19 bzw. vier der 33 inoperablen Patienten trat eine partielle bzw. komplette Remission auf. Insgesamt konnten 14 Patienten sekundaer operiert werden. Unter adaequater Antiemese mit Ondansetron und Dexamethason

Emission reduction in thermal processes for sewage sludge disposal; Emissionsreduzierung bei thermischen Verfahren zur Klaerschlammentsorgung

Energy Technology Data Exchange (ETDEWEB)

Nethe, L.P. [Maerker Umwelttechnik GmbH, Hamburg (Germany)

1998-09-01

Owing to the intensification of treatment processes and the construction of new sewage plants sewage arisings are due to rise considerably. The thermal treatment of sewage sludge which it has not been possible to avoid or utilise is an important and indispensable part of any sewage sludge disposal concept. If equipped with a state-of-the-art flue gas purification process that uses carbonaceous adsorbents (Sorbalit trademark), thermal treatment of sewage sludge can be regarded as an environmentally safe process technique. [Deutsch] Die anfallenden Klaerschlammengen werden durch die Intensivierung der Klaerprozesse und der Bau neuer Klaeranlagen deutlich zunehmen. Die thermische Behandlung nicht vermiedener oder verwerteter Klaerschlaemme stellt einen bedeutenden und unverzichtbaren Teil der Klaerschlamm-Entsorgungskonzepte dar. Bei Installation einer - dem Stand der Technik - entsprechenden Rauchgasreinigung mit dem Einsatz kohlenstoffhaltiger Adsorbentien (Sorbalit {sup trademark}) ist die thermische Behandlung von Klaerschlamm eine umweltsichere Verfahrenstechnik. (orig.)

Supportive treatment with megestrol acetate during radio-(chemo-)therapy. A randomized trial; Supportive Behandlung mit Megestrolacetat waehrend der Radio-(Chemo-)Therapie bei Patienten mit Tumoren im Kopf-Hals-Bereich. Eine randomisierte Studie

Energy Technology Data Exchange (ETDEWEB)

Fietkau, R [Erlangen-Nuernberg Univ., Erlangen (Germany). Strahlentherapeutische Klinik; Riepl, M [Erlangen-Nuernberg Univ., Erlangen (Germany). Strahlentherapeutische Klinik; Kettner, H [Bristol Arzneimittel GmbH, Muenchen (Germany). Medizinische Abt.; Hinke, A [Wissenschaftlicher Service Pharma, Monheim (Germany); Sauer, R [Erlangen-Nuernberg Univ., Erlangen (Germany). Strahlentherapeutische Klinik

1996-03-01

Tumoranorexie und -kachexie bei Patienten mit infauster Prognose ist bekannt. Ob sich ein supportiver Effekt von Megestrolacetat waehrend einer intensiven Radio-(Chemo-)Therapie ergibt, wurde bislang noch nicht untersucht. Dies erfolgte jetzt bei Patienten mit fortgeschritten Tumoren im Kopf-Hals-Bereich. Waehrend und bis sechs Wochen nach der Strahlentherapie erhielten die Patienten des Therapiearmes 160 mg/d Megestrolacetat. Vor, waehrend und nach der Strahlentherapie wurden anthropometrische und laborchemische Parameter bestimmt sowie die subjektive Lebensqualitaet der Patienten mittels des `Quality of life`-Index nach Padilla et al. erfasst. Ergebnisse: Zur endgueltigen Auswertung standen 61 Patienten (Kontrollarm: n=30, Therapiearm: n=31) zur Verfuegung. Ein Patient lehnte nach Randomisation die weitere Teilnahme ab. Je ein Patient im Kontroll- und Placeboarm schieden bei Verdacht auf Nebenwirkungen (Impotenz, Diarrhoe) aus. Weitere Nebenwirkungen wurden nicht beobachtet. Im Kontrollarm verschlechterten sich die Ernaehrungsparameter (Koerpergewicht, Trizepshautfaltendicke) und das subjektive Befinden unter der Bestrahlung sehr schnell und erholten sich anschliessend kaum. Im Gegensatz dazu konnten die mit Megestrolacetat behandelten Patienten diese Werte auf dem Ausgangsniveau stabiliseren. Dieser Unterschied zeigt sich am deutlichsten bei den ausschliesslich oral ernaehrten Patienten (Gewichtsverlust waehrend der Therapie im Kotrollarm: -4,1 kg; im Therapiearm: -0,8 kg; p=0,004), weniger bei den mittels perkutaner endoskopisch kontrollierten Gastrostomie (PEG) versorgten Patienten (Gewichtsverlust im Kontrollarm: -2,4 kg; im Therapiearm: -0,8 kg; p=0,14). Schlussfolgerungen: Die prophylaktische Gabe von Megestrolacetat kann bei Patienten mit Kopf-Hals-Tumoren waehrend einer Radio/(Chemo-)Therapie eine Verschlechterung des Ernaehrungszustands und tendenziell der Lebensqualitaet verhindern.

Cost-effectiveness-analysis: radioiodine or antithyroid drugs as first-line therapy of hyperthyroidism due to Graves` disease; Kosten-Effektivitaets-Analyse: Radioiod oder thyreostatische Medikation bei der Primaerbehandlung der Immunhyperthyreose

Energy Technology Data Exchange (ETDEWEB)

Dietlein, M.; Moka, D.; Dederichs, B.; Schicha, H. [Koeln Univ. (Germany). Klinik und Poliklinik fuer Nuklearmedizin; Hunsche, E.; Lauterbach, K.W. [Koeln Univ. (Germany). Inst. fuer Gesundheitsoekonomie, Medizin und Gesellschaft

1999-06-01

-Effektivitaet. Lebenszeitbezogen wurden die medizinischen Leistungen auf 30 Patientenjahre hochgerechnet. Die Kosten der RITh basierten auf 300 Patienten, deren Entlassung bei 250 MBq Iod-131-Restaktivitaet angenommen wurde. Ergebnis: Kosteneffektivitaet der konservativen Behandlung war bei einer Rezidivrate von 50% oder guenstiger, bei einem Leistungsumfang gemaess den Empfehlungen der Fachgesellschaften und bei einem Zeiteinsatz des Patienten fuer eine ambulante Untersuchung von einem Viertel seines Arbeitstages oder kuerzer zu erwarten. Sofern diese Annahmen nicht vorlagen, wurde die primaere RITh in 1593 von 1944 durchgefuehrten Modellrechnungen zur kosteneffektiven Entscheidung. Konservative Therapieversuche der Rezidivhyperthyreose besassen eine stark kostenhebende Wirkung. Schlussfolgerung: Fuer die Patienten mit erhoehter Rezidivwahrscheinlichkeit im Falle der konservativen Behandlung (Struma, juengeres Lebensalter, persistierend erhoehte TSH-Rezeptor-Antikoerper beziehungsweise erhoehter Technetium-Uptake) bedeutet die primaere RITH eine kosteneffektive Entscheidung. (orig.)

1H-MR-spectroscopy in Anorexia nervosa; characteristic differences between patients and normal controls; 1H-MR-Spektroskopie bei Anorexia nervosa: Charakteristische Unterschiede zwischen Patienten und gesunden Probanden

Energy Technology Data Exchange (ETDEWEB)

Hentschel, F. [ZI Mannheim (Germany). Abt. fuer Neuroradiologie; Moeckel, R.; Schlemmmer, H.P.; Gueckel, F.; Koepke, J.; Georgi, M. [Universitaetsklinik Mannheim (Germany). Inst. fuer Klinische Radiologie; Markus, A.; Goepel, C.; Schmidt, M.H. [ZI Mannheim (Germany). Klinik fuer Kinder- und Jugendpsychiatrie

1999-03-01

Results: The ratio of NAA/PCr in both voxels were not significantly different when comparing patients vs. controls. Patients showed significantly higher ratios of choline-containing components (Cho) or, respectively Cho/PCr and NAA/PCr in the white matter. Distinct, but not significant differences were detected both for m-Ino and m-Ino/PCr in the parieto-occipital region and for the Cho- and m-Ino cotained ratios in the thalamus. Conclusion: AN is not associated with neuronal damage. The ratio of Cho/PCr and NAA/Cho may reflect the disturbance of membrane-turnover. It is possible that the increase of membrane catabolism leads to a hyperosmolar state. The change of m-Ino/PCr ratio may reflect the regulation of osmolarity. (orig.) [Deutsch] Ergebnisse: In den beiden Voxeln wies N-acetylspartat (NAA) als NAA/PCr keine relevanten Unterschiede zwischen Patienten mit AN und Kontrollen auf. Signifikante Unterschiede wurden ausschliesslich fuer Cholin (Cho) resp. die Quotienten Cho/PCr und NAA/Cho in der POR gefunden. Die Ergebnisse fuer myo-Inositol (m-Ino) resp. den Quotienten m-Ino/PCr in der POR und beider relevanter Cho-Metabolitenratios in der ThR unterschieden sich z.T. deutlich, aber nicht signifikant. Diskussion: Unveraendertes NAA als NAA/PCr spricht in Korrelation mit den reversiblen klinischen und hirnmorphologischen Befunden dafuer, dass es bei der AN nicht zu einem neuronalen Untergang kommt. Als Ursache fuer die Erhoehung des Peaks von Cho/PCr ist ein vermehrter Membrankatabolismus bei der AN zu diskutieren, der zu einer Veraenderung des osmotischen Druckes im Gewebe fuehrt. In diesem Zusammenhang ist auch die Bedeutung des m-Ino als Osmolyt zu eroertern, wenngleich die Ergebnisse bei differierenden Einzelwerten fuer m-Ino/PCr noch keine einheitliche Interpretation zulassen. (orig.)

Verwendung von Polypropylen/Polyglactin 910- (PP910- und Polypropylen/Polyglecapron 25 (PP25- Netzen bei Beckenbodenprolaps - eine retrospektive Analyse

Directory of Open Access Journals (Sweden)

Schwegler Ch

2009-01-01

Full Text Available Die Entwicklung von Polypropylen- Implantaten zur Behandlung von Bauchwandhernien stellt einen Meilenstein in der Geschichte der Chirurgie dar. Mit einigen Jahren Verzug folgten die Urogynäkologen den Chirurgen und begannen, Polypropylen-Netze zur Behebung von Beckenbodenvorfällen einzusetzen. PP910-Netze (Vypro II®, Ethicon und PP25-Netze (Ultrapro®, Ethicon werden seit Langem mit gutem Erfolg bei Hernien-Operationen eingesetzt. Das Ziel dieser Studie war herauszufinden, inwieweit sich diese beiden Netze auch für den Einsatz beim Beckenbodenprolaps eignen. Hierzu wurden Fragebögen an Patientinnen versandt, denen in den Jahren 2003 und 2004 diese Netze im Beckenboden implantiert wurden. Die Hauptfragestellungen waren hierbei, inwiefern sich die Symptome des Vorfalles nach der Behandlung verändert hatten und welche Komplikationen nach der Operation aufgetreten waren. Beide Gruppen zeigten nach dem Netzeinsatz deutliche Verbesserungen der Symptomatik bei einer geringen Komplikationsquote. Beim Einsatz von PP910 zeigten sich in 6 % der Fälle Komplikationen, die auf die Implantation des Netzes zurückgeführt werden konnten. Beim Einsatz von PP25 zeigten sogar nur 1,5 % der operierten Frauen netzbedingte Komplikationen. Somit hat sich gezeigt, dass beide Netze gut für die Verwendung im Beckenboden geeignet sind. Vergleicht man die beiden Netze mit anderen Produkten, die derzeit als Implantate im Beckenboden genutzt werden, so zeigt sich ein sehr positives Ergebnis mit signifikant weniger postoperativen Komplikationen unter der Verwendung von PP25-Netzen. Im Rahmen dieser Analyse konnte festgestellt werden, dass PP25 ein sehr sicheres Netz mit ausgesprochen guten Ergebnissen für die Therapie des Beckenbodenprolaps ist.

A QUALIDADE DOS SERVIÇOS CONTÁBEIS COMO FERRAMENTA DE GESTÃO PARA OS ESCRITÓRIOS DE CONTABILIDADE

Directory of Open Access Journals (Sweden)

Tânia Regina Zunino Shigunov

2003-05-01

Full Text Available RESUMO
Sobreviver num mercado competitivo representa o grande desafio das empresas nos dias de hoje, justificando assim corresponder às necessidades e expectativas dos clientes. O presente trabalho tem como tema a qualidade na prestação de serviços contábeis como ferramenta de gestão, procurando munir o escritório de condições que atendam às exigências dos clientes. A contabilidade deixou de ser apenas a escrituração das mutações do patrimônio, passando a ser usada como um instrumento de gestão para o planejamento, controle e tomada de decisões. A contabilidade afim de acompanhar o desenvolvimento das empresas e abertura dos mercados, passou a se preocupar com a questão da qualidade das informações, permitindo aos usuários acompanhar e avaliar a evolução das empresas através da correta aplicação das normas brasileiras de contabilidade e princípios fundamentais de contabilidade como meio para atingir estes fins. Com o advento da tecnologia da informação, permite-se que o contador ofereça excelência nos serviços prestados, pois através das informações contábeis pode fazer parte ativamente do processo decisório das empresas. Adotar a gestão pela qualidade dentro de uma organização contábil significa passar por mudanças significativas, adotar a qualidade através do programa 5 "S" e o ciclo PDCA, cria-se um ambiente de trabalho dinâmico, estimulando trabalho em equipe, motivando os funcionários, atendendo às necessidades dos clientes e tornando a empresa cada vez mais competitiva.

Importance of SPECT/CT for knee and hip joint prostheses; Stellenwert der SPECT/CT bei Knie- und Hueftgelenkprothesen

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Strobel, K.; Steurer-Dober, I.; Huellner, M.W.; Veit-Haibach, P.; Allgayer, B. [Luzerner Kantonsspital (Switzerland). Institut fuer Nuklearmedizin und Roentgendiagnostik

2012-07-15

Complications, such as loosening or infections are common problems after hip or knee arthroplasty. If conventional X-rays are equivocal bone scintigraphy is the classical second-line imaging modality. Single photon emission computed tomography/computed tomography (SPECT/CT) offers metabolic and morphologic information in one imaging step and is becoming increasingly more available in larger hospitals. The SPECT/CT procedure is a promising method and is increasingly being used in daily routine to evaluate joint arthroplasty. The additional benefit compared with classical conventional bone scintigraphy has to be evaluated in further prospective studies. In our hospital SPECT/CT regularly gives important additional information regarding prosthetic joint complications. SPECT/CT is increasingly being used as the second step imaging standard modality if conventional X-rays are equivocal. (orig.) [German] Komplikationen wie Lockerung und Infekt stellen ein haeufiges Problem nach Hueft- und Kniegelenkprothesen dar. Wenn die konventionelle Roentgenaufnahme nicht zum Ziel fuehrt, ist die klassische konventionelle Skelettszintigraphie die am haeufigsten verwendete ''Second-line''-Bildgebung. Die ''single photon emission computed tomography''/CT (SPECT/CT) bietet metabolische und morphologische Informationen bzgl. Prothesenkomplikationen in einem Untersuchungsgang und ist zunehmend in groesseren Kliniken verfuegbar. Die SPECT/CT ist eine viel versprechende Methode und wird im klinischen Alltag bei der Evaluation von Gelenkprothesen zunehmend eingesetzt. Es sind noch mehr prospektive Studien noetig, um die Leistungsfaehigkeit und den Zusatznutzen gegenueber der klassischen Szintigraphie zu evaluieren. In unserer Klinik wird die Knochenszintigraphie bei der Abklaerung von Prothesenkomplikationen zumeist mit einer SPECT/CT kombiniert und liefert regelmaessig wichtige Zusatzinformationen. Die SPECT/CT entwickelt sich zunehmend zum Standard

Preoperative examination of potential renal transplant donors: value of gadolinium-enhanced 3D-MR-angiography in comparison with DSA and urography

International Nuclear Information System (INIS)

Winterer, J.T.; Paul, G.; Einert, A.; Altehoefer, C.; Uhrmeister, P.; Laubenberger, J.

2000-01-01

Purpose: To assess a contrast-enhanced standardized MRA protocol for the presurgical evaluation of potential renal transplant donors. Methods: Twenty-three potential donors for renal transplantations were examined with gadolinium-enhanced, two-phase MR angiograms (1.5 T) and DSA/urography for the number of renal arteries, the presence of aberrant arterial and venous branches, renal artery stenoses and anatomy of the renal collecting system and ureters. The diagnostic value was assessed by evaluating different image processing modalities and interobserver variability. Results: Using maximum intensity projections (MIP) together with multiplanar reformatting (MPR), accessory arteries were detected with a sensitivity/specificity of 100%/98%. Depending on diagnostic experience, exclusive evaluation of MIP yielded a sensitivitiy/specificity of 67-100%/95-100%. Using MIP/MPR, venous depiction was good in 80%, with MIP solely in 30-40%. At least the proximal third of the ureter was visible in 67%. Conclusion: MPR/MIP evaluation of two-phase, contrast-enhanced MRA provides an excellent depiction of renal vessel anatomy for presurgical evaluation of renal transplant donors. Exclusive MIP assessment is less reliable and depends strongly on the examiner's experience. For sufficient visualization of the ureters, either additional measurements or low-dose diuretic injection have to be performed. (orig.) [de

O ensino da contabilidade internacional nos cursos de graduação em ciências contábeis do Brasil

OpenAIRE

Echternacht, Tiago Henrique de Souza

2010-01-01

Esta pesquisa teve como objetivo avaliar a inserção da Contabilidade Internacional nos cursos de graduação em Ciências Contábeis na forma da resolução nº10 do Conselho Nacional de Educação do MEC, nas 87 (oitenta e sete) universidades/faculdades brasileiras, por meio de levantamento de dados visando: conhecer os métodos e meios de ensino utilizados na disciplina, bem como avaliar o estágio atual quanto a sua adoção quer como disciplina específica ou como parte integrante de outra disciplina, ...

Effects of iodine and thyroid hormones in inducing and treating Hashimoto's thyroiditis; Effekte von Iodid und Schilddruesenhormonen bei der Induktion und Therapie einer Thyreoiditis Hashimoto

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Rink, T.; Schroth, H.J.; Holle, L.H.; Garth, H. [Stadtkrankenhaus Hanau (Germany). Abt. fuer Nuklearmedizin

1999-07-01

. der Verlauf der Thyreoglobulin- (Tg-) und Peroxidase-(TPO)-Antikoerper bei bestehender Thyreoiditis Hashimoto unter verschiedenen Therapieformen. Methode: Eine Gruppe von 375 Personen mit weitgehend unauffaelliger Schilddruese erhielt taeglich 200 {mu}g Iod, woechentlich einmalig 1,53 mg Iod oder keine Medikation. In einem zweiten Kollektiv von 377 Patienten mit Thyreoiditis Hashimoto erfolgte eine nichtsuppressive Hormonmedikation, eine suppressive Hormonmedikation, die kombinierte Gabe einer nichtsuppressiven Hormondosis mit Iod (50-150 {mu}g/d), eine reine Iodmedikation mit taeglich 200 {mu}g bzw. keine Therapie. Die mittlere Beobachtungszeit dieser beiden Gruppen lag bei 860 bzw. 848 Tagen. Ergebnisse: Im ersten Kollektiv zeigte sich weder unter Medikation mit taeglich 200 {mu}g Iod noch bei den unbehandelten Patienten ein klarer Anstieg der Antikoerpertiter. Unter Prophylaxe mit woechentlich 1,53 mg Iod fand sich hingegen eine signifikante Erhoehung sowohl der Tg- als auch der TPO-AK-Spiegel, und die Inzidenz einer Thyreoiditis Hashimoto war vierfach hoeher als in den beiden anderen Untergruppen. Die Patienten des zweiten Kollektivs zeigten einen signifikanten Abfall der Tg-AK unter taeglicher Medikation mit bis zu 200 {mu}g Iod, waehrend der Rueckgang der TPO-AK vom TSH-Titer abhing und in der supprimierten Gruppe am ausgepraegtesten war (p<0,0001). Schlussfolgerung: Zur Verringerung der Inzidenz einer Autoimmunthyreopathie ist bei disponierten Patienten eine taeglich zugefuehrte Iodprophylaxe ggf. guenstiger als hochdosierte woechentliche Applikationen. Diese Medikation in Kombination mit einer Hormontherapie kann selbst bei einer bestehenden Thyreoiditis Hashimoto sowohl die Tg- als auch die TPO-AK signifikant senken. (orig.)

Energy saving by enhanced temperature measurement of stock materials of heat- and heat treatment process. Final report; Energieeinsparung durch verbesserte Nutzguttemperaturbestimmung bei Waerm- und Waermebehandlungsprozessen. Schlussbericht

Energy Technology Data Exchange (ETDEWEB)

Ley, I.; Klima, R.

1999-06-01

The essential source of errors for stock temperature measurement in industrial furnaces is the not well enough known emissivity and the reflected radiation. The examined pyrometers turned out to be not precise enough especially in case of reflected radiation. Measures trying to compensate the reflected radiation by measuring it separately or shielding the pyrometer from reflected radiation did not show satisfactory results. The most important result of the project was the development and operational test of a thermoelectric measurement by a so-called thermocouple probe. This probe measures by a thermocouple which is positioned to have a very intensive radiation exchange with the surface of the stock. Thus it can measure the surface temperature almost independently from emissivity. The advantages of the thermocouple probe where shown by installations at a heat treating and a reheating furnace. Because of the continuous measurement the furnaces could be optimised for energy saving or better product quality. The thermocouple probe enables strict optimisation of model aided furnace control and leads to improved quality and energy savings. (orig.) [German] Die wesentlichen Fehlerquellen bei der Messung der Nutzgutoberflaechentemperatur sind der haeufig nicht genau genug bekannte Nutzgut-Emissionsgrad und die an der Nutzgutoberflaeche reflektierte Fremdstrahlung. Die untersuchten auf dem Markt befindlichen Pyrometer erwiesen sich bei vorhandener Fremdstrahlung in Oefen als nicht genau und verlaesslich genug. Sowohl Versuche zur Abschirmung der Fremdstrahlung wie auch zur separaten Messung und Beruecksichtigung der Fremdstrahlung liefern bei wechselnden Prozesszustaenden jedoch keine befriedigenden Ergebnisse. In dieser Arbeit wurde als wichtigstes Ergebnis ein thermoelektrisches Temperaturmessverfahren mittels einer sogenannten Thermoelementsonde entwickelt und betrieblich erprobt. Mit der Thermoelementsonde wird die Nutzgutoberflaechentemperatur mittels eines

First MRI results of the therapeutic course of avascular femoral head necrosis after femoral core decompression; Erste kernspintomographische Ergebnisse des Therapieverlaufs bei avaskulaerer Femurkopfnekrose nach Femurkerndekompression

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Mueller, H.F. [Strahlenklinik und Poliklinik, Virchow Klinikum, Humboldt Univ, Berlin (Germany); Schedel, H. [Strahlenklinik und Poliklinik, Virchow Klinikum, Humboldt Univ, Berlin (Germany); Schneller, A. [Strahlenklinik und Poliklinik, Virchow Klinikum, Humboldt Univ, Berlin (Germany); Eisenschenk, A. [Universitaetsklinikum Benjamin Franklin, Berlin (Germany). Orthopaedische Klinik und Poliklinik; Wicht, L. [Strahlenklinik und Poliklinik, Virchow Klinikum, Humboldt Univ, Berlin (Germany); Siekmann, R. [Strahlenklinik und Poliklinik, Virchow Klinikum, Humboldt Univ, Berlin (Germany); Felix, R. [Strahlenklinik und Poliklinik, Virchow Klinikum, Humboldt Univ, Berlin (Germany)

1997-03-01

The vascular femoral head necrosis is a serious illness, especially when appearing in patients aged 30 to 50 years. Many etiologic factors cause a femoral head necrosis such as, for example, high-dose steroids, abuse of alcohol, defect of bone marrow and trauma of the hip. Often the X-ray photograph leads to the diagnosis in the second stage (ARCO 1992) or in the third stage, when the femoral head has begun to collapse. The stage IIc and III shows an evident enhancement in contrast media in MRI. Contrast enhancement is demonstrated by STIR, FATSAT, T1-weighted and dynamic screening sequence. The characteristics of the contrast media enhancement argue for an active concomitant process of destruction and regeneration. This stage has the best chances for a drug or a surgical therapy. The evaluation of the signal intensity by the dynamic screening sequence is considered as an objective contribution for the staging of the femoral head necrosis. This enables one to differentiate between the curable stage IIc and the stage III, showing the beginning of breakdown of the femoral head. (orig.) [Deutsch] Die avaskulaere Femurkopfnekrose (AVN) ist eine schwerwiegende Erkrankung, die insbesondere bei Patienten im Alter zwischen 30 und 50 Jahren auftritt. Ein Vielzahl von aetiologischen Faktoren wie Einnahme von hohen Dosen Steroiden ueber mehrere Monate, Alkoholmissbrauch, Knochenmarkschaeden und Huefttraumata spielen unabhaengig voneinander eine Rolle. Die Diagnose erfolgt ueblicherweise im zweiten Stadium (ARCO 1992) auf dem Roentgenbild oder im Stadium III, wenn der Femurkopf begonnen hat mechanisch nachzugeben. Eine deutliche kernspintomographisch nachweisbare Kontrastmittelaufnahme zeigen die Stadien ARCO IIc und III, wie die Werte der Dynamic Screening Sequence, der STIR-, der FATSAT und der T{sub 1}-gewichteten Sequenzen belegen. Das Kontrastmittelaufnahmeverhalten spricht fuer einen gleichzeitig aktiven destruierenden und regenerativen Prozess, der fuer einen operativen

Fractures of the atlantoaxial complex in the elderly: assessment of radiological spectrum of fractures and factors influencing imaging diagnosis; Frakturen des Atlas und Axis bei aelteren Patienten: Untersuchung des Radiologischen Spektrums der Frakturen und bedeutsamer Faktoren fuer die Bildgebende Diagnostik

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Lomoschitz, F.M. [Universitaetsklinik fuer Radiodiagnostik, AKH Wien, Wien (Germany); Dept. of Radiology, Harborview Medical Center, Univ. of Washington, Seattle, WA (United States); Blackmore, C.C.; Linnau, K.F.; Mann, F.A. [Dept. of Radiology, Harborview Medical Center, Univ. of Washington, Seattle, WA (United States); Stadler, A. [Universitaetsklinik fuer Radiodiagnostik, AKH Wien, Wien (Germany)

2004-02-01

-axialen Komplexes. Material und Methode: Retrospektive Auswertung von 123 Frakturen des atlanto-axialen Komplexes bei 95 konsekutiven aelteren Patienten (65-102 Jahre, mittleres Alter 79 Jahre). Die atlanto-axialen Frakturen wurden anhand der initial durchgefuehrten bildgebenden Untersuchungen der Halswirbelsaeule klassifiziert. Klinische Angaben einschliesslich neurologischer Status bei Aufnahme und Unfallmechanismus wurden fuer jeden Patienten herangezogen. Die Daten wurden hinsichtlich Frakturtypus sowie Assoziation mit klinischen Veraenderungen und Unfallmechanismus ausgewertet. Ergebnisse: Die Mehrzahl der Patienten hatte Frakturen des Axis (95%), zumeist Dens-Frakturen (74%). Isolierte Frakturen des Atlas (5%) und Kombination mit Frakturen der occipitalen Kondylen (3%) oder der Wirbel C3-C7 (8%) waren selten. Ueberwiegende Unfallursache waren Stuerze (59%). Aeltere Patienten, die bei Verkehrsunfaellen verletzt wurden, hatten signifikant haeufiger isolierte Axis-Frakturen und Typ III Dens-Frakturen (p < 0,02). Zusammenfassung: C2 ist bei atlanto-axialen Frakturen bei aelteren Patienten nahezu immer mitbetroffen. Die Unfallursache hat Einfluss auf den Typ atlantoaxialer Frakturen bei aelteren Patienten. (orig.)

Behaviour of metals during the thermal conversion of Chinese reed; Verhalten von Metallen bei der thermischen Nutzung von Schilfgras

Energy Technology Data Exchange (ETDEWEB)

Klensch, S.; Reimert, R. [Karlsruhe Univ. (T.H.) (Germany). Engler-Bunte-Institut Bereich 1 - Gas, Erdoel und Kohle

1998-12-31

limit values shows that a returning of the fly ash on forest areas is generally possible. Due to the high content of Zn of 1100 mg/kg in the fly ash a returning to agricultural areas is not allowed. (orig.) [Deutsch] Bei den Konversionsverfahren (Vergasung und Verbrennung) zur thermischen Nutzung von Biomasse sollen die anfallenden Rueckstaende (Aschen) moeglichst als Duengemittel auf Forst- oder Agrarflaechen zurueckgefuehrt aber keinesfalls deponiert werden. Hierzu duerfen insbesondere die Schwermetallkonzentrationen in den Aschen gewisse Grenzwerte nicht ueberschreiten. Zur Untersuchung des Schwermetallverhaltens bei der Umwandlung von Biomassen werden Messungen zum Einfluss der Konversionstemperatur (1000-1300 C), der Gasatmosphaere (reduzierend, oxidierend) und der Entstaubungstemperatur (300-750 C) in einer halbtechnischen Anlage bei einem Systemdruck von 1,2 bar durchgefuehrt. Kernstuecke der Anlage sind ein Flugstromreaktor (Reaktionslaenge 2500 mm, Innendruchmesser 70 mm) und ein Kerzenfilter mit 6 Filterelementen vom Typ DIA-Schumalith 10-20 (60/40 x 1500). Der Biomassestrom betraegt 6 kg/h. Die Ergebnisse der Schilfgrasvergasung werden als Mittelwerte ueber den Temperaturbereich von 1000 bis 1160 C bei einer konstanten Filtertemperatur von 550 C in Form von Metallkonzentrationen der Elemente Si, Al, Ca, Fe, Mg, Na, K, Pb, Zn, Cr, Cu und Ni in Schilfgrasasche, Schlacke, Flugasche und Produktgas angegeben. Die Angabe von An- und Abreicherungsfaktoren fuer die verschiedenen Elemente in Flugasche und Schlacke verdeutlichen das Verhalten der Metalle waehrend des Konversionsprozesses. Die Konzentrationen der nichtfluechtigen bzw. schwerfluechtigen Elemente Si, Al, Ca, Fe, Mg und K sind in der Schilfgrasasche, in der Schlacke und in der Flugasche nahezu gleich. Die Konzentrationen der umweltrelevanten Schwermetalle Cr, Pb und Zn sind jeweils in der Schlacke zum Teil deutlich niedriger als in der Schilfgrasasche. Diese Schwermetalle reichern sich in der Flugasche an

Nuclear medicine for treatment of thyroid diseases. Diagnostic evaluation and imaging of the intrathyroid metabolism; Einsatz der Nuklearmedizin bei Schilddruesenerkrankungen. Diagnostik und bildliche Darstellung des intrathyreoidalen Stoffwechsels

Energy Technology Data Exchange (ETDEWEB)

Maul, F.D. [Klinik fuer Nuklearmedizin, Staedtisches Klinikum, Karlsruhe (Germany)

1996-05-01

The diagnostic interest of nuclear medicine is focussed on the imaging and quantification of intrathyroidal iodine metabolism. Most frequently the various forms of autonomy will be investigated by functional scintigraphy. Cold nodules and the differential diagnosis of Graves disease are further indications. In the case of a sufficient iodine uptake hyperthyroidism can be treated by 1311. Severe hyperthyroidism requires a medical pretreatment before radioiodine therapy. A rigid age limit for radioiodine therapy is not necessary. Pregnancy and the suspicion of malignancy are contraindications of a radioiodine therapy. The after-treatment depends on the nature of the treated hyperthyroidism and the posttreatment result. If a focal autonomy could be eliminated a sufficient amount of iodine should be supplied. To prevent the development of hypothyroidism clinical and thyroid hormon controls, and if necessary a substitution with thyroxin is necessary. (orig.) [Deutsch] Bei der Diagnostik und Therapie von Schilddruesenerkrankungen steht die Diagnostik und bildliche Darstellung der intrathyreoidalen Stoffwechselstoerung im Zentrum. Am haeufigsten wird die Schilddruesenfunktionsszintigraphie bei den verschiedenen Formen der autonomen Schilddruesenerkrankungen eingesetzt. Sie dient aber auch der Diagnostik kalter Knoten und der Differenzierung von Autoimmunthyreopathien. Ausreichende Iodspeicherung vorausgesetzt, koennen hyperthyreote Erkrankungen der Schilddruese mit {sup 131}I behandelt werden. (orig./MG)

Comparison of the reliability of subjective evaluation and quantitative measurements of MR signal intensity in inflammations of the intratemporal facial nerve; Vergleich der Reliabilitaet von subjektiver Beurteilung und quantitativer Messung der MR-Signalintensitaet bei Entzuendungen des intratemporalen N. facialis

Energy Technology Data Exchange (ETDEWEB)

Kress, B. [Universitaetsklinikum Heidelberg, Abt. Neuroradiologie (Germany); Abt. Neuroradiologie, Neurologische Klinik, Universitaetsklinik Heidelberg (Germany); Griesbeck, F. [Abt. Neurologie/Psychiatrie, Bundeswehrkrankenhaus Ulm (Germany); Stippich, C.; Sartor, K. [Abt. Neuroradiologie, Neurologische Klinik, Universitaetsklinik Heidelberg (Germany); Baehren, W. [Universitaetsklinikum Heidelberg, Abt. Neuroradiologie (Germany)

2003-01-01

Purpose: To compare in a single-blind study the reliability of quantitative measurements and subjective evaluations of contrast enhancement of the facial nerve in patients with idiopathic facial paralysis. Materials and Methods: Magnetic resonance images with a 0.7 mm slice thickness (surface coil) were obtained in patients with idiopathic facial paralysis before and after administration of Gd-DTPA, 0.1 mmol/kg. The five intratemporal segments of the facial nerve were quantitatively measured and subjectively assessed by five radiologists as to the degree of enhancement. The results were compared as to the reliability of both methods. Results: Using the quantitative measuring method, 175 measurements were calculated from a total of 350 regions of interest. At all 35 measured sites, the five quantitative measurements produced identical results. In contrast, the subjective assessment of the five radiologists arrived at a majority consensus in only 16 sites. A complete agreement was not reached for any measured site. Conclusion: The measured quantitative increase in signal intensity after administration of contrast medium is more reliable than subjective assessment. The quantitative method enables reproducible signal intensity measurements even for different window settings and can be easily and swiftly performed at the workstation. (orig.) [German] Untersuchungsziel: In einer einfach geblindeten Untersuchung sollte geprueft werden, wie hoch die Reliabilitaet der quantitativen Messung des Kontrastmittelanstieges im N. facialis bei idiopathischer Fazialisparese im Vergleich zur subjektiven Einschaetzung ist. Methodik: Bei 7 Patienten mit idiopathischer Fazialisparese wurde eine MRT in Duennschichttechnik (0,7 mm, nativ und nach Gabe von 0,1 mmol GdDTPA/kg) unter Verwendung einer Oberflaechenspule durchgefuehrt. 5 intratemporale Abschnitte des N. facialis wurden sowohl quantitativ als auch subjektiv durch 5 Radiologen beurteilt, und die Methoden wurden im Hinblick auf

Polyzystisches Ovarsyndrom – ein aktueller Überblick über therapeutische Ansätze bei Kinderwunsch und metabolischen Komorbiditäten // PCOS – A Current Overview of Therapeutic Options for Infertility and Metabolic Co-Morbidities

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Lunger F

2017-01-01

resistance.p bKurzfassung: /bDie Diagnose des polyzystischen Ovarsyndroms (PCOS wird anhand der Rotterdam-Kriterien von 2003 gestellt und beinhaltet Oligo- oder Anovulation, Hyperandrogenämie und/oder klinische Zeichen einer Androgenisierung sowie polyzystische Ovarien im Ultraschall. Die Diagnose ist allerdings nicht immer klar. Bei unklarem Ovulationsstatus kann eine Progesteron-Bestimmung in der Mittlutealphase herangezogen werden. Klinische Zeichen einer Hyperandrogenämie werden durch Ethnizität maßgeblich beeinflusst und sollten in der Diagnosestellung berücksichtigt werden. Eine Kombinationsbestimmung von AMH und LH kann herangezogen werden, um Frauen mit sonographischer PCO-Morphologie von Frauen mit PCOS zu unterscheiden. Bei bestehendem Kinderwunsch ist ein erster wichtiger therapeutischer Schritt eine Gewichtsreduktion und Lifestyle- Management. Medikamentöse Therapieansätze beinhalten Clomifen, niedrig dosierte Gonadotropine sowie Metformin. Clomifen stellt aufgrund der hohen Schwangerschaftsraten immer noch die Erstlinientherapie dar. Anstatt mehrfacher Zyklen mit Clomifen sollten Gonadotropine eingesetzt werden, insbesondere bei Clomifen-resistenten Frauen, da eine höhere Ovulation- und Schwangerschaftsrate nachgewiesen wurde. Metabolische Komorbiditäten bei PCOS kommen gehäuft vor und sollten dementsprechend großzügig diagnostiziert und behandelt werden, um Spätfolgen zu reduzieren und/ oder zu vermeiden. Konsensbeschlüsse internatio naler Fachgesellschaften empfehlen ein metabolisches Screening mittels Nüchternblutzucker-Bestimmung sowie oGTT bei allen Frauen mit PCOS oder zumindest bei PCOS-Patientinnen mit zusätzlicher Adipositas, Anovulation oder positiver Familienanamnese. Nüchtern- Insulin und HOMA-Index können eine IR dia gnostizieren. Gezielte Therapien für die metabolische Komorbiditäten beinhalten Diät und adäquate körperliche Betätigung sowie die Einstellung von Hypertonie und Stoffwechselstörungen mit cholesterinsenkenden

ANALISIS RASIO ALTMAN MODIFIKASI PADA PREDIKSI KEBANGKRUTAN PERUSAHAAN PROPERTY DAN REAL ESTATE YANG TERDAFTAR DI BEI

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Anita Tri Widiyawati

2015-10-01

Full Text Available Penelitian ini bertujuan untuk mengetahui pengaruh rasio Altman Modifikasi terhadap prediksi kebangkrutan. Jenis penelitian ini termasuk penelitian kuantitatif. Populasi dalam penelitian ini adalah perusahaan property dan real estate yang terdaftar di BEI. Teknik pengambilan sampel menggunakan purposive sampling sehingga diperoleh sampel sejumlah 32 perusahaan property dan real estate yang menerbitkan laporan keuangannya selama tahun 2011-2013. Teknik analisis data menggunakan regresi logistik (logistic regression. Hasil penelitian menunjukkan bahwa: (1 working capital/total asset tidak berpengaruh terhadap prediksi kebangkrutan; (2 retained earning/total asset tidak berpengaruh terhadap prediksi kebangkrutan; (3 earning before interest and tax/total asset berpengaruh terhadap prediksi kebangkrutan; (4 market value of equity/book value of equity tidak berpengaruh terhadap prediksi kebangkrutan; (5 rasio Altman Modifikasi secara simultan berpengaruh terhadap prediksi kebangkrutan. Rasio Altman Modifikasi terbukti secara bersama-sama dapat digunakan untuk memprediksi kebangkrutan.

Redes de Pesquisa Entre os Egressos do Doutorado em Ciências Contábeis da FEA/USP

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Ilse Maria Beuren

2010-02-01

Full Text Available O estudo objetiva analisar as redes de pesquisa dos egressos do curso de Doutorado em Ciências Contábeis da FEA/USP. A pesquisa documental foi realizada nos currículos Lattes dos doutores em controladoria e contabilidade, formados pela Universidade de São Paulo, no período de 1962 a 2008. Da população de 185 doutores do Doutorado de Ciências Contábeis da FEA/USP, uma amostra de 158 foi selecionada, pois 27 currículos Lattes não estavam disponíveis. Na análise dos dados, utilizou-se estatística descritiva para quantificação da produção científica dos doutores, conforme informações disponíveis nos currículos Lattes. Para análise das redes de pesquisa entre os egressos, utilizou-se o software UNICET®. Os resultados da pesquisa evidenciam as instituições que os egressos estão vinculados atualmente, as funções que exercem nestas instituições, a produção científica dos egressos no período de 1998 a 2008 e as redes de pesquisa predominantes entre os egressos. Constatou-se que a Universidade de São Paulo concentra o maior número de docentes egressos e que a produção científica dos doutores pesquisados está predominantemente publicada em anais de congressos. Quanto às redes, observou-se que estabelecem redes de cooperação com predomínio de ligações fracas em livros, capítulos de livros e textos de revistas/jornais, porém relações de cooperação fortes na publicação de artigos em periódicos. Conclui-se que há ainda necessidade de um fortalecimento nas redes estabelecidas entre os egressos analisados para proporcionar um aprimoramento científico na área contábil.