WorldWideScience

Sample records for dong quai angelica

  1. Dong Quai

    Science.gov (United States)

    ... who had a stroke. Allergies. Anemia. Constipation. Early orgasm in men (premature ejaculation). High blood pressure. Joint ... 3 months. APPLIED TO THE SKIN: For early orgasm in men (premature ejaculation): A specific cream containing ...

  2. Refinansieringsrisiko, DONG og Bankunionen

    DEFF Research Database (Denmark)

    Bechmann, Ken L.

    2014-01-01

    Denne leder indeholder primært redaktørens refleksioner og kommentarer i forlængelse af artiklerne om regulering af refinansieringsrisiko og om salget af aktier i DONG. Endvidere knyttes en række kommentarer til artiklen med Morningstars kritik af ”Om dygtighed, held og stjerner”, der blev bragt ...... Finans/Invest 1/14....

  3. Angelica Sinensis Polysaccharide Prevents Hematopoietic Stem Cells Senescence in D-Galactose-Induced Aging Mouse Model

    Directory of Open Access Journals (Sweden)

    Xinyi Mu

    2017-01-01

    Full Text Available Age-related regression in hematopoietic stem/progenitor cells (HSC/HPCs limits replenishment of the blood and immune system and hence contributes to hematopoietic diseases and declined immunity. In this study, we employed D-gal-induced aging mouse model and observed the antiaging effects of Angelica Sinensis Polysaccharide (ASP, a major active ingredient in dong quai (Chinese Angelica Sinensis, on the Sca-1+ HSC/HPCs in vivo. ASP treatment prevents HSC/HPCs senescence with decreased AGEs levels in the serum, reduced SA-β-Gal positive cells, and promoted CFU-Mix formation in the D-gal administrated mouse. We further found that multiple mechanisms were involved: (1 ASP treatment prevented oxidative damage as total antioxidant capacity was increased and levels of reactive oxygen species (ROS, 8-OHdG, and 4-HNE were declined, (2 ASP reduced the expression of γ-H2A.X which is a DNA double strand breaks (DSBs marker and decreased the subsequent ectopic expressions of effectors in p16Ink4a-RB and p19Arf-p21Cip1/Waf senescent pathways, and (3 ASP inhibited the excessive activation of Wnt/β-catenin signaling in aged HSC/HPCs, as the expressions of β-catenin, phospho-GSK-3β, and TCF-4 were decreased, and the cyto-nuclear translocation of β-catenin was inhibited. Moreover, compared with the positive control of Vitamin E, ASP exhibited a better antiaging effect and a weaker antioxidation ability, suggesting a novel protective role of ASP in the hematopoietic system.

  4. Quais os suplementos alimentares mais utilizados?

    Directory of Open Access Journals (Sweden)

    Alex Bisotto Ferreira

    2016-07-01

    Full Text Available O consumo de suplementos alimentares tem sido muito utilizado e difundido por praticantes de atividade física, em especial a musculação por pessoas com objetivos de melhora em desempenho, redução de gordura corporal, aumento de massa muscular entre outros. Esta pesquisa tem como objetivo revisar sobre quais os suplementos alimentares são utilizados na atualidade, e destacar o mais utilizado. A fonte dos dados é uma pesquisa bibliográfica realizada em média dos últimos 15 anos, foram examinados 232 estudos, sendo selecionados 48. Os suplementos alimentares discutidos nesse artigo foram: Carboidratos, vitaminas e minerais, l-carnitina, creatina, proteínas e aminoácidos. O principal motivo para a utilização de suplementos foi o aumento de massa muscular, predominantemente indicado por professores, instrutores e treinadores, apesar da grande variedade, os suplementos mais utilizados são as proteínas e aminoácidos, e, na maioria dos casos com o intuito de aumentar a massa muscular e melhorar sua recuperação.

  5. Angelica Gets the Spirit Out: Improvisation, Epiphany and Transformation

    Science.gov (United States)

    Pignato, Joseph

    2013-01-01

    This article presents excerpts from a case study describing Angelica Dawson, a New York State music educator. Angelica makes improvisation a central part of her curricula in ways that transcend traditional offerings prevalent in American public schools. Qualitative research methods were used to document Angelica's work over the course of an…

  6. A fluorescence spectroscopy study of traditional Chinese medicine Angelica

    Science.gov (United States)

    Zhao, Hongyan; Song, Feng; Liu, Shujing; Chen, Guiyang; Wei, Chen; Liu, Yanling; Liu, Jiadong

    2013-10-01

    By measuring the fluorescence spectra of Chinese medicine (CM) Angelica water solutions with different concentrations from 0.025 to 2.5 mg/mL, results showed that the fluorescence intensity was proportional to the concentration. Through fluorescence spectra of Angelica solution under different pH values, results indicated coumarin compounds were the active ingredients of Angelica. We also observed fluorescence quenching of the Angelica solution in the presence of spherical silver nanoparticles with radius of 12 nm. Keeping a certain value for the volume of the silver nanoparticles, the fluorescence intensity at 402 nm was linearly proportional to the Angelica in the range of 1-3 mg/mL.

  7. Parigi, Quai Branly. Il dialogo delle nature e delle culture Quai Branly, Paris: The dialogue between natures and cultures

    Directory of Open Access Journals (Sweden)

    Isabella Pezzini

    2012-01-01

    Full Text Available Quai Branly (Museo Nazionale delle Arti e Civilt dAfrica, dAsia, dOceania e delle Americhe a Parigi, inaugurato nel 2006, analizzato da un punto di vista semiotico come un grande dispositivo di riconoscimento e di comunicazione culturale, nelle sue diverse componenti: architettonica, paesaggistica, di allestimento. Si tratta di uno spazio che si vuole fortemente innovativo, e che investe nellintegrazione fra la collezione e le nuove tecnologie della comunicazione. Il museo vuole affermare il valore della diversit delle culture, e costruire uno spazio di possibile dialogo fra di loro, oltre che di esposizione esemplare di artefatti eccezionali. Non solo museo ma anche centro per linsegnamento e la ricerca, nonch spazio a disposizione di diversi pubblici potenziali, compreso quello alla ricerca di intrattenimento: dunque un nuovo museo nel pieno senso del termine.Quai Branly (Africa, Asia, Oceania and Americas Arts and Civilization National Museum in Paris, opened in 2006 is analyzed from a semiotic point of view as a great device for cultural recognition and communication in its different components - architectural, landscape and exhibitions display. Its about a space that builds itself as innovative and that invests on the integration among collections and new communication technologies. The museum aims to state the value of cultures diversity and build a space for possible dialogues among them - besides the exhibition of exceptional artifacts copies. Not only the museum - but also a center for teaching and researching, - the space is available for several potential audiences, including that one that searches for entertainment: therefore, a new museum on its definitions strict sense.

  8. Molecular and Phytochemical Investigation of Angelica dahurica and Angelica pubescentis Essential Oils and Their Biological Activity against Aedes aegypti, Stephanitis pyrioides, and Colletotrichum Species

    Science.gov (United States)

    2014-08-18

    Molecular and Phytochemical Investigation of Angelica dahurica and Angelica pubescentis Essential Oils and Their Biological Activity against Aedes ...against yellow fever mosquito, Aedes aegypti, and azalea lace bugs, Stephanitis pyrioides, than A. pubescentis root oil. The major compounds in the A...dahurica, Angelica pubescentis, internal transcribed spacer region, Colletotrichum species, Aedes aegypti, Stephanitis pyrioides, 1-dodecanol, 1

  9. Ethnobotany of dye plants in Dong communities of China.

    Science.gov (United States)

    Liu, Yujing; Ahmed, Selena; Liu, Bo; Guo, Zhiyong; Huang, Weijuan; Wu, Xianjin; Li, Shenghua; Zhou, Jiangju; Lei, Qiyi; Long, Chunlin

    2014-02-19

    Dyes derived from plants have an extensive history of use for coloring food and clothing in Dong communities and other indigenous areas in the uplands of China. In addition to use as coloring agents, Dong communities have historically utilized dye plants for their value for enhancing the nutritive, medicinal and preservative properties of foods. However, the persistence of plant-derived dyes and associated cultural practices and traditional knowledge is threatened with rapid socio-economic change in China. Research is needed to document the ethnobotany of dye plants in indigenous communities towards their conservation and potential commercialization as a sustainable means of supporting local development initiatives. Semi-structured surveys on plants used for coloring agents and associated traditional knowledge were conducted in fifteen Dong villages of Tongdao County in Hunan Province of South Central China during 2011-2012. Transect walks were carried out with key informants identified from semi-structured surveys to collect samples and voucher specimens for each documented plant species for taxonomic identification. Dong households at the study sites utilize the flowers, bark, stems, tubers and roots of 13 plant species from 9 families as dyes to color their customary clothing and food. Out of the documented plants, a total of 7 are used for coloring food, 3 for coloring clothing and 3 for both food and clothing. Documented plants consist of 3 species that yield black pigments, 3 for brownish red/russet pigments, 3 for red pigments, 2 for dark blue pigments and 2 for yellow pigments. In addition to dyes, the plants have multiple uses including medicinal, ornamental, sacrificial, edible, and for timber. The use of dyes derived from plants persists at the study sites for their important role in expressing Dong cultural identity through customary clothing and food. Further research is needed to evaluate the safety of dye plants, their efficacy in enhancing food

  10. Jagten på afkast, DONG, illikviditet og performanceevaluering

    DEFF Research Database (Denmark)

    Bechmann, Ken L.

    2014-01-01

    I denne leder diskuteres alternative investeringer i lyset af de forskellige artikler, der haves i dette nummer af Finans/Invest. Med udgangspunkt i artiklen om jagten på afkast samt en rapport fra Finanstilsynet om alternative investeringer starter lederen med at beskrive omfanget og den stigende...... fokus, der er på alternative investeringer, og diskuterer endvidere de udfordringer som investorerne har i forhold til specielt risikoen. Lederen nævner her politisk risiko som ét eksempel på en kompliceret risiko og fremhæver her blandt andet hele forløbet omkring DONG som et aktuelt eksempel....... Illikviditet er en anden central risiko, som investorerne må forholde sig til i forbindelse med alternative investeringer. Artiklen om illikviditet i dette nummer viser, at det også er behæftet med udfordringer at behandle illikviditet i forbindelse med værdiansættelse....

  11. Anti-inflammatory and cytotoxic effects of methanol, ethanol, and water extracts of Angelicae Dahuricae Radix.

    Science.gov (United States)

    Wang, Myeong-Hyeon; Jeong, Su-Hyeon; Guo, Huifang; Park, Jun-Beom

    2016-01-01

    Angelicae Dahuricae Radix has been used for the treatment of headaches, rhinitis, and colds in traditional medicine. Methanol, ethanol, and water extracts of Angelicae Dahuricae Radix were collected. A statistically significant reduction in the cellular viability of the mouse leukemic monocyte macrophage cell line was noted after treatment with water extracts of Angelicae Dahuricae Radix. Stimulation with lipopolysaccharides (LPS) for 24 h led to a robust increase in nitric oxide production, but Angelicae Dahuricae Radix at 400 μg/mL concentration significantly suppressed nitric oxide produced by the LPS-stimulated RAW 264.7 cells in 70% ethanol, absolute ethanol, 70% methanol, absolute methanol, and boiling water groups (P ethanol extract of Angelicae Dahuricae Radix suppressed the LPS-stimulated inducible nitric oxide synthase, interleukin-1β, and cycloxygenase-2 expression. Angelicae Dahuricae Radix showed significant cytotoxic effects on the human adenocarcinoma cell line and keratin-forming cell line. (J Oral Sci 58, 125-131, 2016).

  12. Phenolic Compounds of Fresh Roots and Rhizomes of Garden Angelica Angelica Archangelica L.

    Directory of Open Access Journals (Sweden)

    R. M. BASHIROVA

    2014-06-01

    Full Text Available Because in the process of drying and storage of plant materials is a change of genuine compounds, we studied the content of phenolic compounds in freshly drawn angelica roots and rhizomes of the drug Angelica archangelica L. samples had been taken on the territory of the Bashkir State University experimental plot a few days before soil freezing. Fresh rhizomes and roots were ground at room temperature and poured with 96% ethanol. The first portion of the extract containing the glycosides was kept at +5 ° C to precipitate the polysaccharides, and the residual plant material was extracted repeatedly during the day of 96% ethanol to isolate coumarins.After two hours, the first portion of the extract containing glycosides was frozen in a refrigerator, and the remaining part was re-extracted by 96% ethanol for coumarin isolation next day. The second portion representing 80% of the ethanol extract was evaporated to a "tar" state under vacuum at room temperature. Then it was dissolved in CHCl3 and placed in the refrigerator. After a day of keeping the chloroform extract at -10°C, its separation into two fractions was observed: a yellow-orange top and a poor-colored bottom.After separation a gas chromatography-mass spectrometer Thermo Finnigan, 800-Finnigan chromatograph and mass spectrometer of high resolution MAT-95XP "Delta" with “Data System” processing were used.In the alcohol fraction (50% 6.45% there were found catechol, methylcatechol 0.61%, 4.23% 2-methoxy-4-vinylphenol, xanthyletine 0.78%, 4.21% osthol, 10.47% 2,2-dimethyl-3,4-dihydro-2H,5H-pyrano[2,3-b]chromen-5-one, 1.35% kvannin, isoangenomalin 0.37%, 0.8% psoralen and 1.32% prangenin.In the colored fractions 0.41 % bergaptol, 0.41 % marmesin, 0.20 % oroselonе, and 0.07 % neobyakangelikol have been found. High levels of ethyl α-D-glucopyranoside amounting to 35 % were observed in this fraction as well. furocoumarin glycosides are entirely possible to be hydrolysed during the

  13. Effects of an angelica extract on human erythrocyte aggregation, deformation and osmotic fragility.

    Science.gov (United States)

    Wang, X; Wei, L; Ouyang, J P; Muller, S; Gentils, M; Cauchois, G; Stoltz, J F

    2001-01-01

    In Chinese traditional medicine, angelica is widely used for its known clinical effects of ameliorating blood microcirculation. But the mechanism of these beneficial effects still remains unclear. In this work the rheological behaviour of human erythrocytes treated by angelica was studied in vitro. Normal RBCs incubated with an angelica extract at different concentrations (5, 10 or 20 mg/ml) for 60 min at 37 degrees C and then their aggregation, deformation and osmotic fragility were measured with different recently developed optical techniques, namely Erythroaggregometer (Regulest, Florange, France), LORCA (Mechatronics, Amsterdam) and Fragilimeter (Regulest, Florange, France). Experimental results show that angelica (20 mg/ml) significantly decreased normal RBCs' aggregation speed (p<0.01) and could inhibit the hyperaggregability caused by dextran 500. However, the strength of normal RBCs aggregates were not influenced by angelica. When a calcium ionophore A23187 (1.9 microM) was used to harden cell membrane, angelica (20 mg/ml) could significantly (p<0.01) protect erythrocytes against the loss of their deformability even it had no effects on normal RBCs deformation. Finally angelica (5 and 10 mg/ml) decreased significantly (p<0.01) normal RBCs osmotic fragility. In conclusion angelica plays a rheologically active role on human erythrocytes, and this study suggests a possible mechanism for angelica's positive effects against certain cardiovascular diseases.

  14. A reality in the infantile education centre Ding-Dong

    Directory of Open Access Journals (Sweden)

    Isabel García-Baquero Urbiola

    2013-05-01

    Full Text Available The infant education centre Ding-Dong since 1983 –that inaugurated its first infant centre– and now at present –with the Quality and Environmental Certification– continues to be faithful to its pedagogical ideology “the future of the social and environmental economy depends on the quality of the education in the first years of life (0-6 years”. This quality needs to be reinforced and complete don a daily basis and advance towards a sustainable management. To elaborate a report of sustainability is without doubt, an excellent reference of quality and gives a wide credibility of the educative centre. The transparency of the sustainability of the activities of the organisations has a priority of interests for a wide range of interested groups, amongst which are included the educative organisations. One of the most important objectives that sustainable development holds is the demand for innovative alternatives and new ways of thinking, something that should be inherent in any entity which dedicates itself to teaching and training. The present article manifests that the management of the sustainable educational centres have to set up the priority objective of any advanced educational policy.

  15. Metabonomic Analysis of Water Extracts from Different Angelica Roots by 1H-Nuclear Magnetic Resonance Spectroscopy

    Directory of Open Access Journals (Sweden)

    Pui Hei Chan

    2014-03-01

    Full Text Available Angelica Radix, the roots of the genus Angelica, has been used for more than 2,000 years as a traditional medicine in Eastern Asia. The Chinese Pharmacopoeia records more than 100 herbal formulae containing Angelica roots. There are two common sources of Angelica roots, Angelica sinensis from China and A. gigas from Korea. The two species of Angelica roots differ in their chemical compositions, pharmacological properties and clinical efficacy. 1H-NMR metabolic profiling has recently emerged as a promising quality control method for food and herbal chemistry. We explored the use of 1H-NMR metabolic profiling for the quality control of Angelica Radix. Unlike previous work, we performed the metabolic profiling on hot water extracts, so as to mimic the clinically relevant preparation method. Unsupervised principle component analyses of both the full spectral profile and a selection of targeted molecules revealed a clear differentiation of three types of Angelica roots. In addition, the levels of 13 common metabolites were measured. Statistically significant differences in the levels of glucose, fructose and threonine were found between different sources of Angelica. Ferulic acid, a marker commonly used to evaluate Angelica root, was detected in our samples, but the difference in ferulic acid levels between the samples was not statistically significant. Overall, we successfully applied 1H-NMR metabolic profiling with water extraction to discriminate all three sources of Angelica roots, and obtained quantitative information of many common metabolites.

  16. 'The Strange Case of Angelica': affinity between Fantastic and Documental

    Directory of Open Access Journals (Sweden)

    Rita Benis

    2017-01-01

    Full Text Available In 2010, Manoel de Oliveira films The Strange Case of Angélica, a project from the early fifties of the past century. In it, the confrontation between the documentary side of the film (the sequences where the protagonist, Isaac, photographs the workers in the vineyards and the fantastic sequences (the episodes with the ghost of Angelica seems to indicate an affinity. That "shadow of resemblance" Petrarch spoke about to his close friend Giovanni Boccaccio: "... he who imitates must proceed in such a way that what he does is similar but not equal, and that the likeness is not that which exists between the original and the copy, that the more similar the more it is praiseworthy, but instead a likeness which one finds in the similarities between a father and a son, among which, though much difference is made in the aspect, there is, however, as a shadow of resemblance, which the painters call 'aire' (... "(apud Rodrigues 2003: 5. A "family air" as a living correlation that comes to our encounter and which is felt as an immediate understanding (and not as definable evidence. In the film, the shiver that assaults us through the apparition of Angelica seems to announce something that goes beyond this same vision: the eminence of the disappearance of the vineyard workers and their gestures, a loss of connection between Man and Nature. The present affinity - Angelica / diggers - is mirrored in Isaac's immense melancholy, the only person apparently capable of perceiving the landscape, the "air" that this relationship evokes. The whole film is crossed by the glimpse of this indefinable kinship, by the porosity between the sensitive world and the spectral world, the permanent interweaving of visibilities / invisibilities that allow us access to this other cinematographic space-time, more percept than visible, in which, according to Manoel de Oliveira, the phantom of physical reality reveals itself "more real, however, than reality itself" (Baecque and

  17. A Review of the Composition of the Essential Oils and Biological Activities of Angelica Species

    Directory of Open Access Journals (Sweden)

    Kandasamy Sowndhararajan

    2017-09-01

    Full Text Available A number of Angelica species have been used in traditional systems of medicine to treat many ailments. Especially, essential oils (EOs from the Angelica species have been used for the treatment of various health problems, including malaria, gynecological diseases, fever, anemia, and arthritis. EOs are complex mixtures of low molecular weight compounds, especially terpenoids and their oxygenated compounds. These components deliver specific fragrance and biological properties to essential oils. In this review, we summarized the chemical composition and biological activities of EOs from different species of Angelica. For this purpose, a literature search was carried out to obtain information about the EOs of Angelica species and their bioactivities from electronic databases such as PubMed, Science Direct, Wiley, Springer, ACS, Google, and other journal publications. There has been a lot of variation in the EO composition among different Angelica species. EOs from Angelica species were reported for different kinds of biological activities, such as antioxidant, anti-inflammatory, antimicrobial, immunotoxic, and insecticidal activities. The present review is an attempt to consolidate the available data for different Angelica species on the basis of major constituents in the EOs and their biological activities.

  18. Lõuna-Korea õpetab ettevaatlikkust / Dong Hyeon ; intervjueerinud Ave-Lii Idavain

    Index Scriptorium Estoniae

    Hyeon, Dong

    2015-01-01

    Vestlus Lõuna-Korea Pusani riikliku ülikooli majandusprofessori ja Tartu Ülikooli külalisprofessori Dong Hyeon Jung'iga Lõuna-Korea majanduslikust ja poliitilisest olukorrast. Emeriitprofessor oli kaks kuud TTÜ külalisõppejõud

  19. [The effect of Angelica sinensis on adhesion, invasion, migration and metastasis of melanoma cells].

    Science.gov (United States)

    Gu, Qin; Xu, Jian-ya; Cheng, Luo-gen; Xia, Wei-jun

    2007-03-01

    To study the effect of Angelica sinensis on invasion, adhesion, migration and metastasis of B16-BL6 metastatic mouse melanoma cells and discuss its functional mechanism. The proliferation, adhesion, invasion and migration capacity of B16-BL6 metastatic cells was evaluated by MTT assay, adhesion assay and reconstituted basement membrane invasion and migration assay in vitro respectively. Mouse spontaneous melanoma model was used to study the effect of Angelica sinensis on metastasis in vivo. The extract of Angelica sinensis inhibited the proliferation of B16-BL6 metastatic cells and its migration capacity significantly. It regulated bidirectionally the adhesion of B16-BL6 metastatic cells to the basement component laminin while it had no effect on the invasion capacity. In the mouse spotaneous melanoma model, the lung metastatic nodes number and its volume were significantly decreased after continuously treated with the extract of Angelica sinensis at the concentration of 3.67 mg/kg. The extract of Angelica sinensis can inhibit the metastasis of of B16-BL6 metastatic mouse melanoma cells and its mechanism is maybe that Angelica sinensis can inhibit the B16-BL6 cells adhering to the ECM and reduce the migration of B16-BL6 cells.

  20. Clinical effects of Angelica dahurica dressing on patients with I-II phase pressure sores.

    Science.gov (United States)

    Gong, Fen; Niu, Junzhi; Pei, Xing

    2016-11-02

    Angelica dahurica is a well-known traditional Chinese Medicine (TCM), while little information is available about its effects on pressure sores. We aimed to investigate the clinical effect of Angelica dahurica on patients with I-II phase pressure sores, as well as the underlying mechanism. Patients (n = 98) with phase I and phase II pressure sores were enrolled and randomly assigned to control and treated groups. In addition to holistic nursing, patients in the control group received compound clotrimazole cream, while patients in the treated group received continuous 4 weeks of external application of Angelica dahurica dressing. Therapeutic effect was recorded, along with the levels of interleukin-8 (IL-8), epidermal growth factor (EGF), transforming growth factor (TGF)-β, and vascular endothelial growth factor (VEGF). Besides, HaCaT cells were cultured with different concentrations of Angelica dahurica, and then cell viability, clone formation numbers, cell cycle, and levels of cyclin D1 and cyclin-dependent kinase (CDK) 2 were determined. The total effective rate in the treated group was significantly higher than in the control group. Levels of IL-8, EGF, TGF-β, and VEGF were statistically increased by Angelica dahurica. In addition, the cell viability and clone formation numbers were significantly upregulated by Angelica dahurica in a dose-dependent manner. Also, the percentage of cells in G0/G1 phase, and levels of cyclin D1 and CDK2 were significantly elevated. Our results suggest that Angelica dahurica may provide an effective clinical treatment for I-II phase pressure sores.

  1. Source identification and mass balance studies of mercury in Lake An-dong, S. Korea

    Science.gov (United States)

    Han, J.; Byeon, M.; Yoon, J.; Park, J.; Lee, M.; Huh, I.; Na, E.; Chung, D.; Shin, S.; Kim, Y.

    2009-12-01

    In this study, mercury and methylmercury were measured in atmospheric, tributary, open-lake water column, sediment, planktons and fish samples in the catchments area of Lake An-dong, S. Korea. Lake An-dong, an artificial freshwater lake is located on the upstream of River Nak-dong. It has 51.5 km2 of open surface water and 1.33 year of hydraulic residence time. It is a source of drinking water for 0.3 million S. Koreans. Recently, the possibilities of its mercury contamination became an issue since current studies showed that the lake had much higher mercury level in sediment and certain freshwater fish species than any other lakes in S. Korea. This catchments area has the possibilities of historical mercury pollution by the location of more than 50 abandoned gold mines and Young-poong zinc smelter. The objective of this study was to develop a mercury mass balance and identify possible mercury sources in the lake. The results of this study are thus expected to offer valuable insights for the sources of mercury loading through the watershed. In order to estimate the mercury flux, TGM, RGM and particulate mercury were measured using TEKRAN 2537 at the five sites surrounding Lake An-dong from May, 2009 with wet and dry deposition. The fate and transport of mercury in water body were predicted by using EFDC (Environmental Dynamic Fluid Code) and Mercury module in WASP7 (Water quality analysis program) after subsequent distribution into water body, sediments, followed by bioaccumulation and ultimate uptake by humans. The mercury mass balance in Young-poong zinc smelter was also pre-estimated by measuring mercury content in zinc ores, emission gases, sludge, wastewater and products.

  2. Suspected primary immune deficiency in a Donge de Bordeaux dog : short communication

    Directory of Open Access Journals (Sweden)

    R.G. Lobetti

    2002-07-01

    Full Text Available A young Donge de Bordeaux dog was presented with chronic intermittent antibiotic responsive gastrointestinal and respiratory disease. Further evaluation showed bacterial lymphadenitis, bacterial tracheitis, normal white cell and differential cell counts, hypogammaglobulinaemia, and the absence of B-lymphocytes but the presence of T-lymphocytes in the lymphoid tissue stained with lymphocyte markers. As the dog came from a narrow genetic base, with related dogs showing similar clinical signs, possible B-cell congenital immune deficiency was suspected.

  3. Effects of Angelica Oil and the Isolated Butylphthalides on Glutamate-induced Neurotoxicity in PC12 Cells

    Directory of Open Access Journals (Sweden)

    Lu-Si Liu

    2017-03-01

    Full Text Available Angelica sinensis contains a large amount of essential oil (angelica oil, which is rich in phthalide derivatives with a lot of bioactivities. In vitro activity screening of angelica oil from the roots of A. sinensis found that it had concentration-dependent effect on glutamate-induced injury in PC12 cells. Further phytochemical investigation on this angelica oil led to the isolation of nine butylphthalides (1 –9 including two new compounds (1 and 2. Their structures were elucidated by extensive spectroscopic analyses. It is noteworthy that most of the isolated butylphthalides also displayed protective activity at low concentrations and cytotoxicity at high concentrations. These results imply that angelica oil and its main chemical components have protective effect for injured neurons only in appropriate concentration range.

  4. Quais fatores influenciam a decisão de compra de imóveis residenciais?

    Directory of Open Access Journals (Sweden)

    Genival Evangelista de Souza

    2015-02-01

    Full Text Available Este estudo tem como objetivo investigar, através de pesquisa de levantamento, quais fatores e atributos influenciam a decisão de compra de imóvel residencial do tipo apartamento na cidade de São Paulo. A revisão buscou elementos para compreensão do processo decisório do consumidor e estudos que se preocuparam em destacar os atributos considerados pelos consumidores. A pesquisa se valeu de uma amostra não probabilística, por conveniência, e envolveu alunos e profissionais das Instituições de Ensino Superior da Avenida Liberdade e Rua Vergueiro, até a estação Paraíso do Metrô, na cidade de São Paulo. Foi realizado um Survey com 683 respondentes e 470 questionários considerados válidos. O instrumento de pesquisa adveio da revisão da literatura que permitiu identificar uma lista de atributos vinculados às seguintes dimensões: apartamento, condomínio e localização. Visando reduzir os atributos a fatores que pudessem refletir a escolhas das pessoas, foi feita uma análise fatorial exploratória, que destacou os fatores: exigências de suporte gerais, necessidades complementares, conforto espacial, suporte ao prédio, aproveitamento da natureza, localização e privacidade.

  5. New Designs in Circulation Areas And Museums the Case of the Quai Branly Museum

    Directory of Open Access Journals (Sweden)

    Nihan CANBAKAL ATAOĞLU

    2016-05-01

    Full Text Available During the Pre-Modern Era of 1970s; new buildings questioning general typologies and offering advances in terms of design and function are started to be built. Architects not only looked for unattempted block structures but also their quest for unattempted block structures were continued for internal places, too and internal implicit setups were designed using ortographic tools like plans and sections. In today’s museums; new and multiple circulation routes are designed; in which visitors do not read books from beginning to end but choose their own paths and walk through the exhibition as if in a labyrinth on their own. These radical perceptional, spatial changes and spatial scenarios are particularly emphasized in museum buildings. These new spatial arrangements in circulation areas are offering new spatial experiences with irregular gaps in sections, regular but non-geometric floor plans, vagueness of the borders, striking colors, patterns and materials, differentiated circulation parts (stairs, moving stairways, elevators, platforms, bridges. In the study; Jean Nouvel’s Quai Branly Museum (2006 which is a recent example of this striking change will be analyzed thorough spatial experiences, observations, syntactic analysis technique and semantic examinations.   

  6. Metabolic fingerprinting of Angelica sinensis during growth using UPLC-TOFMS and chemometrics data analysis

    Science.gov (United States)

    2013-01-01

    Background The radix of Angelica sinensis is widely used as a medicinal herbal and metabolomics research of this plant during growth is necessary. Results Principal component analysis of the UPLC-QTOFMS data showed that these 27 samples could be separated into 4 different groups. The chemical markers accounting for these separations were identified from the PCA loadings plot. These markers were further verified by accurate mass tandem mass and retention times of available reference standards. The study has shown that accumulation of secondary metabolites of Angelica sinensis is closely related to the growth periods. Conclusions The UPLC-QTOFMS based metabolomics approach has great potential for analysis of the alterations of secondary metabolites of Angelica sinensis during growth. PMID:23453085

  7. [Preliminary study on standardization of production and processing of Angelicae Sinensis Radix pieces].

    Science.gov (United States)

    Nie, Rui-Jie; Wang, Ying-Zi; Sun, Zhen-Yang; Wang, Si-Yu; Zhang, Jing-Zhen

    2017-12-01

    Study on the standardization of Chinese materia medica is an important action for modernization and globalization for traditional Chinese medicine. Standardization on the processing of Chinese herbal pieces is an important part in the study on standardization of Chinese materia medica, so it is of great significance to establish the technical processing standards of Angelicae Sinensis Radix pieces for improving its quality. In this study, single factor experiment was designed to optimize the softening, cutting and drying processes of Angelicae Sinensis Radix. With ferulic acid, Angelicae Sinensis Radix polysaccharide, volatile oil and extracts (water and ethanol) content as the quality index, the effects of different softening, cutting and drying processes on the contents of the five components in Angelicae Sinensis Radix were analyzed, and the normalized distance evaluation method was used to analyze the experimental data. The results showed that the content of five components in Angelicae Sinensis Radix was affected by different softening methods and drying temperature, but the thickness of slice had little effect on the content. The best preparation process for Angelicae Sinensis Radix was as follows: Non-medicinal parts were removed; mildewed and rot as well as moth-eaten parts were removed; washed by the flowing drinking water; stacked in the drug pool; moistening method was used for softening, where 125 mL water was sprayed for every 1 kg of herbs every 2.5 h; upper part of herbs covered with clean and moist cotton, and cut into thin slices (1-2 mm) after 15 h moistening until appropriate softness, with disk thickness of 1-2 cm, then received blast drying for 6 h at 55 ℃, and turned over for 2 times during the drying. Copyright© by the Chinese Pharmaceutical Association.

  8. Estrutura de capital: o papel das fontes de financiamento nas quais companhias abertas brasileiras se baseiam

    Directory of Open Access Journals (Sweden)

    Wilson Tarantin Junior

    2015-01-01

    Full Text Available ResumoEste estudo avaliou a estrutura de capital de companhias abertas brasileiras, no período de 2005 a 2012, verificando o papel das fontes de financiamento nas quais tais companhias se baseiam. Para tanto, foi avaliada a proporção das dívidas em 3 fontes distintas: as instituições financeiras, o mercado de capitais e as fontes com taxas de juros subsidiadas, estas últimas representando um fator institucional da economia brasileira. Foi utilizada uma amostra de 95 empresas, dentre as 150 maiores empresas com ações negociadas na Bolsa de Valores, Mercadorias e Futuros de São Paulo (BM&FBOVESPA. Por meio de modelos com dados em painel, os resultados mostram que as fontes de financiamento impactam a formação da estrutura de capital das empresas, exercendo influência tanto na alavancagem quanto na maturidade das dívidas. Em relação à alavancagem, empresas que têm maior proporção de seus recursos captados no mercado de capitais são mais alavancadas. O mesmo não acontece com as empresas que têm maior proporção de recursos subsidiados. Em relação à maturidade das dívidas, recursos de diferentes maturidades são captados em diferentes fontes: os recursos de menores maturidades são captados em instituições financeiras e os recursos de maiores maturidades são captados no mercado de capitais e nas fontes com taxas de juros subsidiadas - leia-se Banco Nacional de Desenvolvimento Econômico e Social (BNDES. Comparando-se os recursos do mercado de capitais com os recursos subsidiados, verifica-se que os primeiros têm maior maturidade. Tal resultado pode ser justificado em virtude do crescimento do mercado de capitais brasileiro nos últimos anos, a partir de 2009, de modo que as companhias estão se baseando no mercado de capitais para seus financiamentos de maior maturidade e nos recursos subsidiados, do BNDES, para seus financiamentos de maturidades intermediárias.

  9. Anti-inflammatory and analgesic activity of r.a.p . ( Radix Angelicae ...

    African Journals Online (AJOL)

    The objective of this paper was to study the anti-inflammatory and analgesic effects of Radix Angelicae Pubescentis (R.A.P) ethanol extracts. Three classic anti-inflammatory models and two analgesic models were used in this research. In anti-inflammatory tests, all the extracts have a certain inhibition on the acute ...

  10. Clinical assessment of the efficacy and safety of T-Angelica Herbal ...

    African Journals Online (AJOL)

    The safety, efficacy, and acceptability of T-Angelica Herbal Tonic (THAT), a phytomedicinal beverage was studied over a period of one week in ten healthy volunteers for regulatory purposes. The study started after an overnight fast with each subject drinking 150ml of the beverage every night and every morning for a period ...

  11. Angelica Sinensis attenuates inflammatory reaction in experimental rat models having spinal cord injury.

    Science.gov (United States)

    Xu, Jun; E, Xiao-Qiang; Liu, Hui-Yong; Tian, Jun; Yan, Jing-Long

    2015-01-01

    This study was aimed to evaluate the effect of Angelica Sinensis on experimental rat models in which spinal cord injury was induced by studying different factors. Different factors causing inflammation play a key role in pathophysiology of SCI. Here three groups of rats (n=15, each was used). These included a sham control group where only laminectomy was performed, SCI group where SCI was induced and AS/SCI group where although SCI was induced but Angelica Sinensis was also administered to study its effect and draw a comparison with control. The expression of I-kBα and NF-kB p65 was also studied using western blotting and after recording optical density (OD) values of western blots. MPO activity was used to measure the effect of 20 mg/kg Angelica Sinensis. The levels of proinflammatory cytokines TNF-α, IL-1β and IL-6 were also studied. As compared with SCI group and sham control it was observed that Angelica Sinensis significantly reduced the expression of I-kBα and NF-kB p65, (PSinensis in rat models can attenuate the secondary damage caused by SCI and thus help in controlling the pathology of SCI in rats.

  12. Insecticidal effect of furanocoumarins from fruits of Angelica archangelica L. against larvae Spodoptera littoralis Boisd

    Czech Academy of Sciences Publication Activity Database

    Pavela, R.; Vrchotová, Naděžda

    2013-01-01

    Roč. 43, MAY 2013 (2013), s. 33-39 ISSN 0926-6690 R&D Projects: GA MŠk(CZ) ED1.1.00/02.0073 Keywords : Angelica archangelica * furanocoumarins * essential oils * plant extracts * spodoptera littoralis * botanical insecticides * insecticidal activity Subject RIV: EH - Ecology, Behaviour Impact factor: 3.208, year: 2013

  13. Selective effects of the extract from Angelica archangelica L. against Harmonia axyridis (Pallas)—An important predator of aphids

    Czech Academy of Sciences Publication Activity Database

    Pavela, R.; Žabka, M.; Vrchotová, Naděžda; Tříska, Jan; Kazda, J.

    2013-01-01

    Roč. 51, NOV 2013 (2013), s. 87-92 ISSN 0926-6690 Institutional support: RVO:67179843 Keywords : Angelica archangelica * Harmonia axyridis * furanocoumarins * botanical insecticides * aphids Subject RIV: EH - Ecology, Behaviour Impact factor: 3.208, year: 2013

  14. Effect of Angelica Sinensis on liver fibrosis after radiotherapy combined with transarterial chemoembolization for rabbits with VX 2 tumor

    International Nuclear Information System (INIS)

    Long Qingyun; Zhou Yunfeng; Hu Jinxiang; Zhou Jun; Le Tao

    2008-01-01

    Objective: To evaluate the effect of Angelica Sinensis on liver fibrosis after radiotherapy (RT) combined with transarterial chemoembolization(TACE) for rabbits with VX 2 tumor, and the mechanism of anti-hepatic fibrosis. Methods: Fifty New Zealand white rabbits were divided randomly into three groups: Control group (n=10) was given saline 2 ml by gastroduodenal artery, model group (n=10) was given pingyangmycin 1 mg and iodized oil 0.2 ml, and exposed to single fraction of 20 Gy, Angelica group (n=30) undergoing RT combined with TACE was given Angelica Sinensis injection. According to different doses of Angelica Sinensis, Angelica group was divided into low-dose group (4 ml/kg), middle dose group (6 ml/kg) and high-dose group (8 ml/kg), twice per week for 4 weeks. Serum levels of HA, LN, PCIII, CIV and liver specimens were obtained at the end of 6th week after RT combined with TACE. The histological changes were determined by HE, VG staining and TGF-β1 immunohistochemistry staining. Results: Stages of liver fibrosis in the model group were mostly stages II and III, and stages of liver fibrosis in the Angelica group were mostly stages I, there was significant difference between the model group and the Angelica group, and stages of liver fibrosis were associated with Angelica intercention treatment (r=0.7631, P<0.01). Serum HA, LN, PCIII and CIV in the model group were higher than those in the control group(P<0.01), TGF-β1 expression in the Angelica group was significantly reduced compared with the wodel group and different doses of Angelica group showed dose-effect (r=0.4427, P<0.01). Conclusions: Angelica Sinensis injection has inhibitive effect on liver fibrosis after RT combined with TACE for rabbits with VX 2 tumor, the mechanism of anti-hepatic fibrosis might possibly be associated with down-regulating TGF-β1. (authors)

  15. [Professor DONG Gui-rong's experience for the treatment of peripheral facial paralysis].

    Science.gov (United States)

    Cao, Lian-Ying; Shen, Te-Li; Zhang, Wei; Chen, Si-Hui

    2012-05-01

    Professor DONG Gui-rong's theoretical principle and manipulation points for peripheral facial paralysis were introduced in details from the angels of syndrome differentiation, timing, acupoint prescription and needling methods. For the syndrome differentiation and timing, the professor emphasized to check the treatment timing and follow the symptoms, which should be treated by stages, besides, it was necessary to find and distinguish the reason and nature of diseases to have a combined treatment of tendons and muscles. For the acupoint prescription and needling methods, he has proposed that the acupoints selection should be compatible of distal and lacal, and made a best of Baihui (GV 20) to regulate the whole yang qi, also he has paid much attention to the needling methods and staging treatment. Under the consideration of late stage of peripheral facial paralysis, based on syndrome differentiation Back-shu points have been selected to regulate zang-fu function, should achieve much better therapeutic effect.

  16. ZHANG Ting-dong (张亭栋)—— A Pioneer in Treating Leukemia with Arsenous Acid

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Prof. ZHANG Ting-dong, male, was born in Wuqiao County, He-bei Province on Nov. 8,1932, and in 1950 graduated from Harbin Medical University. And from 1960 to 1963 he studied in and then graduated from Western Doctors'class for Learning Traditional Chinese Medicine(TCM).

  17. Detecting Long-term Trend of Water Quality Indices of Dong-gang River, Taiwan Using Quantile Regression

    Science.gov (United States)

    Yang, D.; Shiau, J.

    2013-12-01

    ABSTRACT BODY: Abstract Surface water quality is an essential issue in water-supply for human uses and sustaining healthy ecosystem of rivers. However, water quality of rivers is easily influenced by anthropogenic activities such as urban development and wastewater disposal. Long-term monitoring of water quality can assess whether water quality of rivers deteriorates or not. Taiwan is a population-dense area and heavily depends on surface water for domestic, industrial, and agricultural uses. Dong-gang River is one of major resources in southern Taiwan for agricultural requirements. The water-quality data of four monitoring stations of the Dong-gang River for the period of 2000-2012 are selected for trend analysis. The parameters used to characterize water quality of rivers include biochemical oxygen demand (BOD), dissolved oxygen (DO), suspended solids (SS), and ammonia nitrogen (NH3-N). These four water-quality parameters are integrated into an index called river pollution index (RPI) to indicate the pollution level of rivers. Although widely used non-parametric Mann-Kendall test and linear regression exhibit computational efficiency to identify trends of water-quality indices, limitations of such approaches include sensitive to outliers and estimations of conditional mean only. Quantile regression, capable of identifying changes over time of any percentile values, is employed in this study to detect long-term trend of water-quality indices for the Dong-gang River located in southern Taiwan. The results show that Dong-gang River 4 stations from 2000 to 2012 monthly long-term trends in water quality.To analyze s Dong-gang River long-term water quality trends and pollution characteristics. The results showed that the bridge measuring ammonia Long-dong, BOD5 measure in that station on a downward trend, DO, and SS is on the rise, River Pollution Index (RPI) on a downward trend. The results form Chau-Jhou station also ahowed simialar trends .more and more near the

  18. Research of angelica sinensis (Oliv) diels new strain DGA2000-02 selection

    International Nuclear Information System (INIS)

    Xie Hongmei; Li Wenjian; Hao Jifang; Liu Jing; Liu Xiaorui; Jing Yanming; Shang Hushan; Liu Rongqing; He Baogang; Wang Chunming; Zhang Guoli; Chen Shuzhen

    2008-01-01

    Angelica sinensis(Oliv)Diets new strain DGA2000-02 was selected successfully by Institute of Modern Physics, Chinese Academy of Sciences, Dryland Farming Research and Extension Center of Dingxi Prefecture, etc. According to the program of new strain selection, this new strain was selected for several year's after the dry seeds of Gansu Angelica sinensis(Oliv)Diels 90-01 was irradiated by ions of 55 MeV/u 40 Ar +15 . During the period of year 2005-2007, region experiments of Angelica sinensis (Oliv)Diels new strain DGA2000-02 were developed in Minxian, Weiyuan, Zhangxian and Longxi etc. Average yield of the fresh DGA2000-02 Angelica was 10 621.5 kg/hm 2 , and 15.0% production was increased more than control (for 1 386.0 kg/hm 2 of 90-01). The growth stage of the DGA2000-02 was 790 d, and it has deep purple stem and yellow-white root. The quality analysis results are as follows: total ash content is 4.2% and acidast ash content is 0.4%, 16% and 33.3% better than control, respectively; the lixivium is 61.4%, i.e., 4.4% more than the standard of Pharmacopoeia of People's Republic of China (2005 edition); the ferullc acid content is 0.148%, i.e., 2.96 times ligher than the standard. All these results showed that the quality of the DGA2000-02 was better significantly than both control and the standard. It can be grown appropriately at the high, cold and dankness regions at the altitude of 2000-2600 m and with a annual precipitation of 500-600 mm. (authors)

  19. The ethanolic extract of ashitaba stem (Angelica keskei [Miq.] Koidz) as future antituberculosis

    OpenAIRE

    Sri Agung Fitri Kusuma; Yoppi Iskandar; Mutiara Ayu Dewanti

    2018-01-01

    Considering the easy contagion of tuberculosis (TB) disease spread and the emergence of multidrug-resistant TB, which directly impacts the failure of therapeutic goals and mortality rates increasing, TB disease control remains to be the main concern of continuous health development effort. Therefore, the discovery of new TB drug is needed. This research assessed the new natural anti-TB drug from the ethanolic extract of Angelica keiskei stem obtained from Lombok, Indonesia. The objectives of ...

  20. Data Mining of Acupoint Characteristics from the Classical Medical Text: DongUiBoGam of Korean Medicine

    Directory of Open Access Journals (Sweden)

    Taehyung Lee

    2014-01-01

    Full Text Available Throughout the history of East Asian medicine, different kinds of acupuncture treatment experiences have been accumulated in classical medical texts. Reexamining knowledge from classical medical texts is expected to provide meaningful information that could be utilized in current medical practices. In this study, we used data mining methods to analyze the association between acupoints and patterns of disorder with the classical medical book DongUiBoGam of Korean medicine. Using the term frequency-inverse document frequency (tf-idf method, we quantified the significance of acupoints to its targeting patterns and, conversely, the significance of patterns to acupoints. Through these processes, we extracted characteristics of each acupoint based on its treating patterns. We also drew practical information for selecting acupoints on certain patterns according to their association. Data analysis on DongUiBoGam’s acupuncture treatment gave us an insight into the main idea of DongUiBoGam. We strongly believe that our approach can provide a novel understanding of unknown characteristics of acupoint and pattern identification from the classical medical text using data mining methods.

  1. Molecular and phytochemical investigation of Angelica dahurica and Angelica pubescentis essential oils and their biological activity against Aedes aegypti, Stephanitis pyrioides, and Colletotrichum species.

    Science.gov (United States)

    Tabanca, Nurhayat; Gao, Zengping; Demirci, Betul; Techen, Natascha; Wedge, David E; Ali, Abbas; Sampson, Blair J; Werle, Chris; Bernier, Ulrich R; Khan, Ikhlas A; Baser, Kemal Husnu Can

    2014-09-03

    In this study, Angelica dahurica and Angelica pubescentis root essential oils were investigated as pest management perspectives, and root samples were also analyzed genetically using the nuclear ribosomal internal transcribed spacer (ITS) region as a DNA barcode marker. A. pubescentis root essential oil demonstrated weak antifungal activity against Colletotrichum acutatum, Colletotrichum fragariae, and Colletotrichum gloeosporioides, whereas A. dahurica root essential oil did not show antifungal activity. Conversely, A. dahurica root essential oil demonstrated better biting deterrent and insecticidal activity against yellow fever mosquito, Aedes aegypti, and azalea lace bugs, Stephanitis pyrioides, than A. pubescentis root oil. The major compounds in the A. dahurica oil were found as α-pinene (46.3%), sabinene (9.3%), myrcene (5.5%), 1-dodecanol (5.2%), and terpinen-4-ol (4.9%). α-Pinene (37.6%), p-cymene (11.6%), limonene (8.7%), and cryptone (6.7%) were the major compounds found in the A. pubescentis oil. In mosquito bioassays, 1-dodecanol and 1-tridecanol showed antibiting deterrent activity similar to the positive control DEET (N,N-diethyl-3-methylbenzamide) at 25 nmol/cm(2) against Ae. aegypti, whereas only 1-tridecanol showed repellent activity in human-based cloth patch bioassay with minimum effective dosages (MED) of 0.086 ± 0.089 mg/cm(2) (DEET = 0.007 ± 0.003 mg/cm(2)). In larval bioassays, 1-tridecanol was more toxic with an LC50 value of 2.1 ppm than 1-dodecanol having an LC50 value of 5.2 ppm against 1-day-old Ae. aegypti larvae. 1-Dodecanol and 1-tridecanol could be useful for the natural mosquito control agents.

  2. [Effects of Astragali Radix combined with Angelicae Sinensis Radix on the proliferation of hematopoietic stem cells senescence model in mice].

    Science.gov (United States)

    Zhang, Ke-Sheng; Chen, Ling-Bo; Huang, Xiao-Ping; Deng, Chang-Qing

    2017-11-01

    The aim is to study the effect and its mechanism of Astragalus Radix combined with Angelicae Sinensis Radix on the proliferation of hematopoietic stem cells(HSCs) in senescence model. After drug-containing plasma of rats was prepared via intragastric administration, HSCs of mice were cultured in vitro, and then they were divided into blank control group, model group, blank plasma group, Astragalus Radix + Angelicae Sinensis Radix 1∶1 group and 10∶1 group, Angelicae Sinensis Radix plasma group, and Astragalus Radix plasma group. HSCs senescence model was induced by using tert-butyl hydrogen peroxide(t-BHP), and intervened by drug-containing plasma. Cells senescence rate was tested by SA-β-galactosidase staining method; cell cycle distribution was determined by flow cytometry; Cyclin D1, P21, and P53 mRNA were measured with RT-PCR, and Cyclin D1 protein expression was measured by Western blot. Results showed that after being induced by t-BHP, senescence rate of HSCs was increased; cell proliferation ability was decreased; count of G₀/G₁ phase cells was increased; count of G₂/M+S phase cells was reduced; Cyclin D1 expression was down-regulated while P53, P21 expression was up-regulated, which were reversed by Astragalus Radix + Angelicae Sinensis Radix 1∶1 and 10∶1, single Angelicae Sinensis Radix, and single Astragalus Radix plasma. Furthermore, the above effects were most obvious in Astragalus Radix+Angelicae Sinensis Radix 1∶1 group. These results suggested that t-BHP can promote HSCs senescence and reduce cell proliferation ability. Angelicae Sinensis Radix, Astragalus Radix and their combinations can inhibit HSCs senescence, promote HSCs proliferation as well as cell cycle conversion; moreover, the effects of 1∶1 Astragalus Radix+Angelicae Sinensis Radix were strongest. The mechanisms may be related to up-regulating the expression of cell cycle positive regulator, down-regulating the expression of cell cycle negative regulator, thus promoting

  3. On the Melody Types between the North and the South Dong Folks%南北侗族民歌的旋律类型探究

    Institute of Scientific and Technical Information of China (English)

    苏金梅

    2014-01-01

    South and North Dong Minority , the two branches of Dong , have remarkable differences in the music style of folk songs . South Dong'folk song is mild and obscure while North Dong'folk song is lyric and straightforward . The formation of their differences is closely related to their melody types :the melody type of South Dong's folk song is mainly small wave while the melody type of North Dong's folk song is with ups and small wave ;though both South and North Dong's folk songs enjoy small wave type , there are differences in the music development mode of small wave type . The differences of melody types in South and North Dong's folk songs are connected with their own cultural ecology , i . e , the differences of South and North Dong area's ecological and cultural environment mold out the characteristics of South and North Dong's folk song which is reflected in their different melody types .%南、北侗族作为侗族旗下的两个分支,在民歌音乐风格方面差别显著:南侗民歌平和、含蓄,北侗民歌抒情、直白。这种差异的形成与二者的旋律类型存有紧密联系:南侗民歌的旋律类型仅以小波浪式为主,北侗民歌以跌宕式与小波浪式两种类型为主;南北侗族民歌虽都喜好小波浪式,但二者的小波浪式在音乐发展模式上也不同。而南、北侗族民歌旋律类型的差异正好与彼此所处的文化生态是相互耦合的,也即是说,南、北侗族地区生态文化环境的差异模塑出南北侗族民歌的特性,这一特性在其民歌的旋律类型中得以表现。

  4. Elemental analysis of the Taiwanese health food Angelica keiskei by INAA

    International Nuclear Information System (INIS)

    Chien-Yi Chen

    2002-01-01

    The health food Angelica keiskei, planted and consumed as an oriental herb, was sampled from five farms in Taiwan. The determination of minor and trace elements identified in the roots, fresh leaves and stems of the plant, as well as in end-products such as tea bags and capsules, is essential for estimating the recommended daily intake for ensuring optimum health safety. Samples were homogenized prior to freeze-drying, and were irradiated with a neutron flux at about 2.0 x 10 12 n x cm -1 x s -1 . A total of 17 elements were analyzed using INAA. In the collected samples the elements exist in widely differing concentrations, ranging from 10 5 to 10 -2 μg/g for different farms. Aluminum was found more highly concentrated in roots than in any other part of the plant. Selenium ws the only element analyzed down to 10 -1 μg/g in the leaves. Meanwhile, arsenic was also found in the roots and stems at levels of nearly 10 -2 μg/g. The elemental concentrations and maximum daily intake (MDI) of this herb are compared with those of Angelica sinensis (Danggui in Mandarin), Ligusticum chuanxiony (Chuanxiong in Mandarin) and Panax ginseng (Ginseng in Mandarin) as well as with the recommended daily dietary intake values for Taiwanese consumers, developed by the WHO. (author)

  5. Development of Genome-Wide SSR Markers from Angelica gigas Nakai Using Next Generation Sequencing.

    Science.gov (United States)

    Gil, Jinsu; Um, Yurry; Kim, Serim; Kim, Ok Tae; Koo, Sung Cheol; Reddy, Chinreddy Subramanyam; Kim, Seong-Cheol; Hong, Chang Pyo; Park, Sin-Gi; Kim, Ho Bang; Lee, Dong Hoon; Jeong, Byung-Hoon; Chung, Jong-Wook; Lee, Yi

    2017-09-21

    Angelica gigas Nakai is an important medicinal herb, widely utilized in Asian countries especially in Korea, Japan, and China. Although it is a vital medicinal herb, the lack of sequencing data and efficient molecular markers has limited the application of a genetic approach for horticultural improvements. Simple sequence repeats (SSRs) are universally accepted molecular markers for population structure study. In this study, we found over 130,000 SSRs, ranging from di- to deca-nucleotide motifs, using the genome sequence of Manchu variety (MV) of A. gigas, derived from next generation sequencing (NGS). From the putative SSR regions identified, a total of 16,496 primer sets were successfully designed. Among them, we selected 848 SSR markers that showed polymorphism from in silico analysis and contained tri- to hexa-nucleotide motifs. We tested 36 SSR primer sets for polymorphism in 16 A. gigas accessions. The average polymorphism information content (PIC) was 0.69; the average observed heterozygosity ( H O ) values, and the expected heterozygosity ( H E ) values were 0.53 and 0.73, respectively. These newly developed SSR markers would be useful tools for molecular genetics, genotype identification, genetic mapping, molecular breeding, and studying species relationships of the Angelica genus.

  6. A Metabolism-Based Synergy for Total Coumarin Extract of Radix Angelicae Dahuricae and Ligustrazine on Migraine Treatment in Rats

    Directory of Open Access Journals (Sweden)

    Shan Feng

    2018-04-01

    Full Text Available Radix Angelicae dahuricae, containing coumarins, which might affect cytochrome P450 enzyme (CYP450 activity, has been co-administered with ligustrazine, a substrate of CYP450s, for the clinical treatment of migraine. However, whether a pharmacokinetic-based synergy exists between Radix Angelicae dahuricae and ligustrazine is still unknown. In this study, the total coumarin extract (TCE of Radix Angelicae dahuricae (50 mg/kg, orally reinforced the anti-migraine activity of ligustrazine by declining head scratching, plasma calcitonin gene-related peptide, and serum nitric oxide, as well as increasing plasma endothelin levels in rats (p < 0.05. Moreover, the pharmacokinetic study reflected that TCE potentiated the area under the concentration–time curve of ligustrazine and prolonged its mean retention time in rats (p < 0.05. Besides, the IC50 for TCE, imperatorin and isoimperatorin inhibiting ligustrazine metabolism were 5.0 ± 1.02, 1.35 ± 0.46, 4.81 ± 1.14 µg/mL in human liver microsomes, and 13.69 ± 1.11, 1.19 ± 1.09, 1.69 ± 1.17 µg/mL in rat liver microsomes, respectively. Moreover, imperatorin and isoimperatorin were CYP450s inhibitors with IC50 < 10 µM for CYP1A2, 2C9, 2D6, and 3A4. Therefore, this study concluded that Radix Angelicae dahuricae could increase ligustrazine plasma concentration and then reinforce its pharmacological effect by inhibiting its metabolism through interference with CYP450s. This could be one mechanism for the synergy between Radix Angelicae dahuricae and ligustrazine on migraine treatment.

  7. A globalização vista do norte e do sul: quais os seus mecanismos sociais?

    Directory of Open Access Journals (Sweden)

    Olivier Giraud

    Full Text Available Procura-se, neste artigo, definir a globalização a partir da identificação de uma série de mecanismos sociais por meio dos quais essa age diretamente sobre os comportamentos individuais e coletivos ou ainda sobre a maneira de pensar, as crenças, as identidades, as formas de institu-cionalização, etc. O que constitui a especificidade da globalização é justamente o fato de ser um fenômeno social que se manifesta em todo o planeta. Será que os mecanismos específicos que caracterizam o funcionamento da globalização são aplicáveis nas mesmas condições nas sociedades que apresentam fortes diferenças como é o caso das sociedades do Norte e do Sul? Diferentes mecanismos ligados ao reforço da competição econômica internacional e às suas conseqüências sobre o sistema de proteção social, ou ainda ligados à difusão de normas e de práticas políticas no contexto da globalização, serão abordados em seguida. De forma mais sistemática, quatro cenários convergência, divergência, hibridação e recomposição das hierarquias internacionais serão apresentados no contexto de uma análise comparativa dos efeitos da globalização nas sociedades do Sul e do Norte.

  8. Evaluating origins and water seepage rates at the subdam A of the Dong Mo reservoir using environmental isotope technique

    International Nuclear Information System (INIS)

    Bui Dac Dung; Trinh Van Giap; Dang Anh Minh; Nguyen Van Hoan

    2008-01-01

    Environmental isotope techniques have been world-widely used for investigating origins and the rates of the seepage - leakage water at reservoir dams. We have conducted a research on the use of environmental isotope techniques for evaluating the origin of the seepage water and the seepage rate at the sub dam A of the Dong Mo reservoir. The main works were collecting water samples, analyzing for 18 O/ 16 O, 2 H(D)/ 1 H ratios, analyzing for 3 H(T) and chemical contents. Findings of the project showed that: a) Waters at the piezometers on the top and the 1st roof are not originated from lake water; b) Waters at the piezometers on 1st and 2nd levels, as well as seepage waters at the dam toe are mixed of lake and ground waters, and the old river bed could be the channel for ground water upcoming from beneath the dam body; c) The transit times of water from the lake to the observation points are from 3 to 4 months, and the seepage velocity is of about 1.1x10 -3 cm/s; d) The findings from tritium analyses show that all waters around the Dong Mo area are recent waters recharged regularly by meteoric water. (author)

  9. Assessment of waters and sediments impacted by drainage at the Young Dong coal mine site, South Korea.

    Science.gov (United States)

    Woo, Kwangje; Lee, Ju Y; Ji, Won H; Khim, Jeehyeong

    2012-01-01

    This study focused on the assessment of the geochemistry and hydrology of the Imgok Creek-Young Dong tributary for the design of a field coal mine drainage treatment system. Examination of this site showed that the pH was greatly lowered by the addition of the Young Dong water, except in the month of March. The alkalinity was also affected; the concentrations of iron, aluminum, and sulfate were elevated at sites below the confluence; of these, iron was particularly problematic. High iron concentrations were primarily restricted to the acid rock drainage (ARD) (YD-9) water sources, whereas high aluminum concentrations were seen in both the ARD and in some of the upstream water sources. The acidity was primarily due to ferrous and ferric iron with a lesser amount of aluminum acidity. Except for the sampling in March, the flow was dominated by the ARD. This hydrologic condition resulted from the loads of iron, aluminum, sulfate, and acidity, among other constituents, that were dominated by the ARD. Finally, treatment activities should primarily focus on the ARD and specifically seek to remove ferrous and ferric iron from the treatment system.

  10. Formação do professor bilíngue para surdos: de quais competências estamos falando?

    Directory of Open Access Journals (Sweden)

    Veridiane Pinto Ribeiro

    2017-01-01

    Full Text Available Na perspectiva das políticas de inclusão, a partir da década de 1990, os surdos teriam direito à educação bilíngue, ou seja, teriam acesso a sua primeira língua, ou língua natural, que é a Língua Brasileira de Sinais (Libras - L1 e, posteriormente, em Língua Portuguesa que seria sua segunda língua (L2. Diante dessa diretriz político-pedagógica, a presente pesquisa buscou identificar quais as competências pertinentes à formação do professor bilíngue (PB para surdos através de pesquisa de campo realizada com professores que atuam na educação de surdos no município de ltajaí - SC. Com base em seus depoimentos, buscamos traçar o perfil do profissional bilíngue, à luz da literatura corrente. Segundo as professoras entrevistadas não há investimento suficiente para que os profissionais construam as competências necessárias para o exercício de uma educação bilíngue condizente com os apelos da comunidade surda e das diretrizes oficiais. Para se identificar um professor com competência em educação bilíngue para surdos parte-se da premissa de que este privilegia as peculiaridades que se configuram em sua cultura visual na intermediação dos conhecimentos em detrimento da reabilitação da fala e de habilidades fonológicas para a apropriação da escrita. Por outro lado, destaca- se a necessária incorporação do conhecimento da história, cultura e identidades surdas, respeitando essas peculiaridades e baseando-se nelas para construir sua práxis.

  11. Separation of two major chalcones from Angelica keiskei by high-speed counter-current chromatography.

    Science.gov (United States)

    Kil, Yun-Seo; Nam, Joo-Won; Lee, Jun; Seo, Eun Kyoung

    2015-08-01

    Angelica keiskei (Shin-sun cho) is an edible higher plant with the beneficial preventive effects on cancer, hypertension, and coronary heart disease. Two bioactive chalcones of Shin-sun cho, xanthoangelol (1) and 4-hydroxyderricin (2), were separated simultaneously by using high-speed counter-current chromatography with a two-phase solvent system composed of n-hexane-EtOAc-MeOH-H2O (9:5:9:4). Only nonconsuming processes, solvent fractionations and Sephadex LH-20 column chromatography, were conducted as presteps. Xanthoangelol (1, 35.9 mg, 99.9 % purity at 254 and 365 nm) and 4-hydroxyderricin (2, 4.4 mg, 98.7 % purity at 254 nm and 98.8 % purity at 365 nm) were successfully purified from 70 mg of the processed extract from A. keiskei. The structures of two compounds were confirmed by (1)H- and (13)C-NMR analysis.

  12. [Influence of different processing methods on Angelica sinensis polysaccharides from same origin].

    Science.gov (United States)

    Lv, Jieli; Chen, Hongli; Duan, Jinao; Yan, Hui; Tang, Yuping; Song, Bingsheng

    2011-04-01

    To study the influences of different processing methods on the content of Angelica sinensis polysaccharides (APS) from the same origin. The contents of neutral polysaccharides and acidic polysaccharides in various samples of A. sinensis were determined by phenol-sulfuric acid and carbazole-sulfuric acid method, respectively. The proliferation ability of lymphocyte was detected by MTT method after the cells were cultured with different concentrations of APS from two samples processed by different methods. The different processing methods had different effects on the contents of polysaccharide. The maximum content of APS (26.03%) was found in the sample processed by microwave drying medium-fired, but the minimum content of APS (2.25%) was found in the sample processed by vacuum drying at 50 TC. Furthermore, the APS (high concentration group, P methods have different effects on the contents of APS and the proliferation ability of lymphocytes.

  13. Modulation by angelica sinensis the expression of tumor necrosis factor αin radiation-induced damage of the lung

    International Nuclear Information System (INIS)

    Xie Conghua; Zhou Yunfeng; Peng Gang; Liu Hui; Chen Ji; Xia Mingtong

    2005-01-01

    Objective: To investigate the ability of Angelica Sinensis to affect the radiation-induced tumor necrosis factor α(TNF-α) release in the animal model, so as to find an effective method in reducing the lung toxicity after thoracic irradiation. Methods: The chest of 72 C57BL/6 mice were exposed to either sham irradiation or single fraction of 12 Gy after having been randomized into 4 groups: 1. 9 mice received neither irradiation nor Angelica Sinensis but received i. p injection of NS 20 ml/ (kg·d) (NT group); 2. 9 mice received Angelica Sinensis only but no irradiation though receiving i. p, NS(AS group); 3. 27 mice received whole lung 12 Gy irradiation and i. p, NS without Angelica Sinensis (XRT group) and 4. 27 mice received both i. p, 25% Angelica Sinensis 20 ml/(kg·d) and whole lung 12 Gy irradiation(AS/XRT group). The TNF-α mRNA expression in the lung tissue were quantified by 'real-time' quantitative reverse transcriptase polymerase chain reaction (RT-PCR). Immunohistochemical detection method (Streptavidin-Peroxidase method) and positive cell counting were used for objective quantification of TNF-α protein expression. Results: NT and AS group exhibited low level of TNF-α protein expression with positive cell counts between 8 and 17. And there was an significantly elevated level of TNF-α positive inflammatory cells in XRT group (P<0.01). The number of the positive cells in AS/XRT group was between NT and AS group and XRT group with the difference between AS/XRT group and XRT group significant (P<0.01). The results of 'real-time' quantitative RT-PCR showed that the relative mRNA expression of cytokine TNF-α in XRT group was significantly higher than the nonirradiated groups (P<0.01). The lung tissue of the mice which were treated by Angelica Sinensis revealed only a minor radiation-mediated TNF-α response on mRNA level, but the statistical comparison of the TNF-a mRNA expressions between the XRT and AS/XRT groups was not significant (P=0.078), which

  14. Angelica sinensis polysaccharides promotes apoptosis in human breast cancer cells via CREB-regulated caspase-3 activation

    International Nuclear Information System (INIS)

    Zhou, Wei-Jie; Wang, Sheng; Hu, Zhuang; Zhou, Zhen-Yu; Song, Cai-Juan

    2015-01-01

    Angelica sinensis polysaccharide (ASP) is purified from the fresh roots of Angelica sinensis (AS). This traditional Chinese medicine has been used for thousands of years for treating gynecological diseases and used in functional foods for the prevention and treatment of various diseases, such as inflammation and cancer. The antitumor activity of ASP is related to its biological activities, because it suppresses a variety of pro-proliferative or anti-apoptotic factors that are dramatically expressed in cancer cells of given types. In this study, we show that angelica sinensis polysaccharide induced apoptosis in breast cancer cells of T47D over-expressing the Cyclic AMP response element binding protein (CREB), inducing apoptosis-related signaling pathway activity. The result also found that ASP caused cell death was linked to caspase activity, accompanied by the loss of mitochondrial membrane potential, cytochrome c release, and Bax translocation from the cytosol to the mitochondria. We found that ASP significantly affected the poly-ADP-ribose polymerase (PARP), Bcl-2 Associated X Protein (Bax), Bcl-2, Bcl-xL and apoptotic protease activating facter-1 (Apaf1) protein expression in a dose- and time-dependent manner. DAPI staining and Flow cytometry were used to analyze apoptosis. The nude mice xenograft model was used to evaluate the antitumor effect of ASP in vivo. ASP has profound antitumor effect on T47D cells, probably by inducing apoptosis through CREB signaling pathway. Thus, these results suggest that ASP would be a promising therapeutic agent for breast cancer. - Highlights: • CREB and Caspase-3 signaling pathways are involved in the ASP induced breast cancer cells apoptosis. • ROCK1/Mlc signaling pathway plays a critical role in this ASP-mediated apoptosis. • Angelica sinensis polysaccharide (ASP) affected the PARP, Bax, Bcl-2, Bcl-xL and Apaf1 protein expression. • The activation of CREB and ROCK1 promotes caspase-3 activation and apoptosis induced

  15. Angelica sinensis polysaccharides promotes apoptosis in human breast cancer cells via CREB-regulated caspase-3 activation

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Wei-Jie; Wang, Sheng [Department of Breast and Thyroid Surgery, Huaihe Hospital, Henan University, Kaifeng 475000 (China); Hu, Zhuang, E-mail: zhuanghu475000@sina.com [Department of Breast and Thyroid Surgery, Huaihe Hospital, Henan University, Kaifeng 475000 (China); Zhengzhou Center for Disease Control and Prevention, Zhengzhou 475000 (China); Zhou, Zhen-Yu; Song, Cai-Juan [Department of Breast and Thyroid Surgery, Huaihe Hospital, Henan University, Kaifeng 475000 (China); Zhengzhou Center for Disease Control and Prevention, Zhengzhou 475000 (China)

    2015-11-20

    Angelica sinensis polysaccharide (ASP) is purified from the fresh roots of Angelica sinensis (AS). This traditional Chinese medicine has been used for thousands of years for treating gynecological diseases and used in functional foods for the prevention and treatment of various diseases, such as inflammation and cancer. The antitumor activity of ASP is related to its biological activities, because it suppresses a variety of pro-proliferative or anti-apoptotic factors that are dramatically expressed in cancer cells of given types. In this study, we show that angelica sinensis polysaccharide induced apoptosis in breast cancer cells of T47D over-expressing the Cyclic AMP response element binding protein (CREB), inducing apoptosis-related signaling pathway activity. The result also found that ASP caused cell death was linked to caspase activity, accompanied by the loss of mitochondrial membrane potential, cytochrome c release, and Bax translocation from the cytosol to the mitochondria. We found that ASP significantly affected the poly-ADP-ribose polymerase (PARP), Bcl-2 Associated X Protein (Bax), Bcl-2, Bcl-xL and apoptotic protease activating facter-1 (Apaf1) protein expression in a dose- and time-dependent manner. DAPI staining and Flow cytometry were used to analyze apoptosis. The nude mice xenograft model was used to evaluate the antitumor effect of ASP in vivo. ASP has profound antitumor effect on T47D cells, probably by inducing apoptosis through CREB signaling pathway. Thus, these results suggest that ASP would be a promising therapeutic agent for breast cancer. - Highlights: • CREB and Caspase-3 signaling pathways are involved in the ASP induced breast cancer cells apoptosis. • ROCK1/Mlc signaling pathway plays a critical role in this ASP-mediated apoptosis. • Angelica sinensis polysaccharide (ASP) affected the PARP, Bax, Bcl-2, Bcl-xL and Apaf1 protein expression. • The activation of CREB and ROCK1 promotes caspase-3 activation and apoptosis induced

  16. [DONG's extraordinary acupoints for the ovarian function of polycystic ovary syndrome:a randomized controlled pilot trial].

    Science.gov (United States)

    Cao, Yu; Zhang, Li; Zhao, Danyang; Liu, Zhishun

    2017-07-12

    To preliminary assess the efficacy of DONG 's extraordinary acupoints for the ovarian function of polycystic ovary syndrome. Fifty-six patients were randomized into an acupuncture group and a western medication group. In the acupuncture group, the acupoints were Fuke, Huanchao, Tianhuang (Yinlingquan, SP 9), Renhuang (Sanyinjiao, SP 6), Guanyuan (CV 4), Zigong (EX-CA 1). The treatment was used twice a week for continuous 12 weeks. In the western medication group, patients were given diane-35 for 3 menstrual cycles, once a day for 21 days with 7 days between the two sessions. The ratio of luteinizing hormone/flitropin (LH/FSH) was taken as the primary index, while the secondary indices were serum testosterone (T), FSH, LH, body mass index (BMI), the condition of ovary and menstruation. ①After treatment, the ratio of LH/FSH declined in both the two groups ( P 0.05). ②T, LH and BMI dropped in the two groups ( P 0.05). ③The size of ovary did not change significantly after treatment in the two groups (both P >0.05), but the reduction degree of ovary size of the acupuncture group was larger than that of the western medication group ( P ovary number of more than 10 foliiculi in single ovary in the acupuncture group reduced compared with that before treatment ( P ovary number with the above feature was not significantly different between the two groups ( P >0.05). ④The times and days of menstruation within 3 months increased significantly in the two groups (all P 0.05). DONG 's extraordinary acupoints could improve the ovarian function of polycystic ovary syndrome, whose effect is similar as diane-35.

  17. Research on the use of environmental isotopes technique for safety assessment of the Dong-mo reservoir

    International Nuclear Information System (INIS)

    Bui Dac Dung; Trinh Van Giap; Le Tien Quan; Dang Anh Minh; Dinh Bich Lieu; Nguyen Manh Hung; Pham Quoc Ky; Ta Hong Duc; Dang Van Lap; Phung Van Luc

    2007-01-01

    To help end-users generate information on the rate and origin of the seepage - leakage water of the sub dam A (FA) of the Dong-mo reservoir we have conducted a research project in the 2005-2006 period. The experiences gained in this project are needed for recommending further use in other reservoirs. The main works were collecting water samples, analyzing for 18 O/ 16 O, 2 H(D)/ 1 H ratios, analyzing for 3 H(T) and chemical contents, then drawing conclusions about the origin of the seepage water and the seepage rate at the dam FA. Findings of the project showed that: a) Waters at the piezometers on the top and the 1st roof are not originated from lake water; b) Waters at the piezometers on 1st and 2nd levels, as well as seepage - leakage waters at the dam toe are mixed of lake and ground waters, and the old river bed could be the channel for ground water upcoming from beneath the dam body; c) The transit times of water from the lake to the observation points are from 3 to 4 months, and the velocity is of about 1.1x10 -3 cm/s; d) The findings from tritium analyses show that all waters around the Dong-mo area are recent waters recharged regularly by meteoric water. Based on the findings of the project we have recommended that the environmental isotope technique be applied for further investigations of origin of leakage and seepage water at other dams. (author)

  18. Speech at the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instruction on Western Medicine Doctors Learning Traditional Chinese Medicine

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhu

    2009-01-01

    @@ Respected leaders, distinguished guests, venerable seniors and comrades, Today, the Meeting Commemorating the 50th Anniversary of Chairman MAO Ze-dong's Important Instructions on Western Medicine Doctors Learning Traditional Chinese Medicine was inaugurated by the Chinese Association of Integrative Medicine, and it is also an important occasion to review the past and look forward to the future.

  19. Specific PCR Identification between Peucedanum praeruptorum and Angelica decursiva and Identification between Them and Adulterant Using DNA Barcode.

    Science.gov (United States)

    Han, Bang-Xing; Yuan, Yuan; Huang, Lu-Qi; Zhao, Qun; Tan, Ling-Ling; Song, Xiang-Wen; He, Xiao-Mei; Xu, Tao; Liu, Feng; Wang, Jian

    2017-01-01

    The traditional Chinese medicine (TCM) Qianhu and Zihuaqianhu are the dried roots of Peucedanum praeruptorum and Angelica decursiva , respectively. Since the plant sources of Qianhu and Zihuaqianhu are more complex, the chemical compositions of P. praeruptorum and A. decursiva are significantly different, and many adulterants exist because of the differences in traditional understanding and medication habits. Therefore, the rapid and accurate identification methods are required. The aim was to study the feasibility of using DNA barcoding to distinguish between Traditional Chinese medicine Qianhu ( Peucedanum praeruptorum ), Zihuaqianhu ( Angelica decursiva ), and common adulterants, based on internal transcribed spacer (ITS) sequences, as well as specific PCR identification between P. praeruptorum and A. decursiva . The ITS sequences of P. praeruptorum , A. decursiva , and adulterant were studied, and a phylogenetic tree was constructed. Based on the ITS barcode, the specific PCR primer pairs QH-CP19s/QH-CP19a and ZHQH-CP3s/ZHQH-CP3a were designed for P. praeruptorum and A. decursiva , respectively. The amplification conditions were optimized, and specific PCR products were obtained. The results showed that the phylogenetic trees constructed using the BI and MP methods were consistent, and P. praeruptorum and A. decursiva sequence haplotypes formed their own monophyly. The experimental results showed that in PCR products, the target bands appeared in the genuine drug and not in the adulterant, which suggests the high specificity of the two primer pairs. The ITS sequence was ideal DNA barcode to identify P. praeruptorum , A. decursiva , and adulterant. The specific PCR is a quick and effective method to distinguish between P. praeruptorum and A. decursiva . Peucedanum praeruptorum and Angelica decursiva sequence haplotypes formed their own monophyly.The ITS sequence was ideal DNA barcode to identify P. praeruptorum , A. decursiva , and adulterant.Specific PCR is a

  20. Prescribed Renoprotective Chinese Herbal Medicines Were Associated with a Lower Risk of All-Cause and Disease-Specific Mortality among Patients with Chronic Kidney Disease: A Population-Based Follow-Up Study in Taiwan

    Directory of Open Access Journals (Sweden)

    Chuan-Fa Hsieh

    2017-01-01

    Full Text Available Chinese herbal medicines (CHMs containing aristolochic acid (AA are associated with chronic kidney disease (CKD, but some prescribed CHMs have been shown to possess renoprotective effects. We conducted a nationwide retrospective cohort study to delineate the role of prescribed CHMs on the CKD progression. Renoprotective CHM (RPCHM was defined if a CHM contained dong chong xia cao (Cordyceps sinensis (Berk. Sacc., da huang (Rheum palmatum L, huang qi (Astragalus membranaceus, dan shen (Salvia miltiorrhiza Bge., and dong quai (Angelica sinensis (Oliv. Diels or belonged to specific mixture herbal formulations (Yishen capsule, Saireito, or Wen Pi Tang. Subjects who had ever used AA-containing CHMs, had cancer or HIV prior to CKD diagnosis, or died within the first month of CKD diagnosis were excluded. A total of 11,625 patients were eligible subjects. The adjusted hazard ratio (aHR for all-cause mortality was 0.6 (p < 0.001 and 0.6 (p = 0.013 among subjects receiving RPCHMs containing Angelica sinensis and those receiving other RPCHMs, respectively. For CKD-related mortality, the aHR among subjects receiving RPCHMs containing Angelica sinensis was 0.6 (p = 0.025. The use of specific RPCHMs, especially those that contained Angelica sinensis, was associated with a lower risk of mortality among CKD patients.

  1. Biotransformation of isofraxetin-6-O-β-d-glucopyranoside by Angelica sinensis (Oliv.) Diels callus.

    Science.gov (United States)

    Zhou, Di; Zhang, Yuhua; Jiang, Zhe; Hou, Yue; Jiao, Kun; Yan, Chunyan; Li, Ning

    2017-01-15

    Isofraxetin-6-O-β-d-glucopyranoside, identified from traditional medicinal herbal Xanthoceras sorbifolia Bunge, has been demonstrated to be a natural neuroinflammatory inhibitor. In order to obtain more derivatives with potential anti-neuroinflammatory effects, biotransformation was carried out. According to the characteristics of coumarin skeleton, suspension cultures of Angelica sinensis (Oliv.) Diels callus (A. sinensis callus) were employed because of the presence of diverse phenylpropanoids biosynthetic enzymes. As a result, 15 products were yielded from the suspension cultures, including a new coumarin: 8'-dehydroxymethyl cleomiscosin A (1), together with 14 known compounds. Their structures were elucidated by extensive spectroscopic analysis. Furthermore, the biotransformed pathways were discussed. Among them, compound 13 was transformed from isofraxetin-6-O-β-d-glucopyranoside, while compounds 1-6, 10-12, 14-15 were derived from the culture medium stimulated by the substrate. The biotransformation processes include hydroxylation, oxidation and esterification. Furthermore, their inhibitory effects on lipopolysaccharide (LPS)-activated nitric oxide (NO) production were evaluated in BV2 microglial cells. It is worth noting that, 1, 1'-methanediylbis(4-methoxybenzene) (3), obtucarbamates A (5), 2-nonyl-4-hydroxyquinoline N-oxide (10) and 1H-indole-3-carbaldehyde (11) exhibited significant inhibitory effect against neuroinflammation with IC 50 values at 1.22, 10.57, 1.02 and 0.76μM respectively, much stronger than that of the positive control minocycline (IC 50 35.82μM). Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Effects of gamma irradiation on the yields of volatile extracts of Angelica gigas Nakai

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Hye-Young; Kim, Jun-Hyoung [Department of Food and Nutrition, Chosun University, Gwangju 501-759 (Korea, Republic of); Song, Hyun-Pa; Kim, Dong-Ho; Byun, Myung-Woo [Radiation Food Science and Biotechnology Team, Korea Atomic Energy Research Institute, Daejeon 305-353 (Korea, Republic of); Kwon, Joog-Ho [Department of Food Science and Technology, Kyungpook National University, Daegu 702-701 (Korea, Republic of); Kim, Kyong-Su [Department of Food and Nutrition, Chosun University, Gwangju 501-759 (Korea, Republic of)], E-mail: kskim@chosun.ac.kr

    2007-11-15

    The study was carried out to determine the effects of gamma irradiation on the volatile flavor components including essential oils, of Angelica gigas Nakai. The volatile organic compounds from non- and irradiated A. gigas Nakai at doses of 1, 3, 5, 10 and 20 kGy were extracted by a simultaneous steam distillation and extraction (SDE) method and identified by GC/MS analysis. A total of 116 compounds were identified and quantified from non- and irradiated A. gigas Nakai. The major volatile compounds were identified 2,4,6-trimethyl heptane, {alpha}-pinene, camphene, {alpha}-limonene, {beta}-eudesmol, {alpha}-murrolene and sphatulenol. Among these compounds, the amount of essential oils in non-irradiated sample were 77.13%, and the irradiated samples at doses of 1, 3, 5, 10 and 20 kGy were 84.98%, 83.70%, 83.94%, 82.84% and 82.58%, respectively. Oxygenated terpenes such as {beta}-eudesmol, {alpha}-eudesmol, and verbenone were increased after irradiation but did not correlate with the irradiation dose. The yields of active substances such as essential oil were increased after irradiation; however, the yields of essential oils and the irradiation dose were not correlated. Thus, the profile of composition volatiles of A. gigas Nakai did not change with irradiation.

  3. Bioactive Peptides from Angelica sinensis Protein Hydrolyzate Delay Senescence in Caenorhabditis elegans through Antioxidant Activities

    Directory of Open Access Journals (Sweden)

    Qiangqiang Wang

    2016-01-01

    Full Text Available Since excessive reactive oxygen species (ROS is known to be associated with aging and age-related diseases, strategies modulating ROS level and antioxidant defense systems may contribute to the delay of senescence. Here we show that the protein hydrolyzate from Angelica sinensis was capable of increasing oxidative survival of the model animal Caenorhabditis elegans intoxicated by paraquat. The hydrolyzate was then fractionated by ultrafiltration, and the antioxidant fraction (<3 kDa was purified by gel filtration to obtain the antioxidant A. sinensis peptides (AsiPeps, which were mostly composed of peptides with <20 amino acid residues. Further studies demonstrate that AsiPeps were able to reduce the endogenous ROS level, increase the activities of the antioxidant enzymes superoxide dismutase and catalase, and decrease the content of the lipid peroxidation product malondialdehyde in nematodes treated with paraquat or undergoing senescence. AsiPeps were also shown to reduce age pigments accumulation and extend lifespan but did not affect the food-intake behavior of the nematodes. Taken together, our results demonstrate that A. sinensis peptides (AsiPeps are able to delay aging process in C. elegans through antioxidant activities independent of dietary restriction.

  4. Effects of gamma irradiation on the yields of volatile extracts of Angelica gigas Nakai

    International Nuclear Information System (INIS)

    Seo, Hye-Young; Kim, Jun-Hyoung; Song, Hyun-Pa; Kim, Dong-Ho; Byun, Myung-Woo; Kwon, Joog-Ho; Kim, Kyong-Su

    2007-01-01

    The study was carried out to determine the effects of gamma irradiation on the volatile flavor components including essential oils, of Angelica gigas Nakai. The volatile organic compounds from non- and irradiated A. gigas Nakai at doses of 1, 3, 5, 10 and 20 kGy were extracted by a simultaneous steam distillation and extraction (SDE) method and identified by GC/MS analysis. A total of 116 compounds were identified and quantified from non- and irradiated A. gigas Nakai. The major volatile compounds were identified 2,4,6-trimethyl heptane, α-pinene, camphene, α-limonene, β-eudesmol, α-murrolene and sphatulenol. Among these compounds, the amount of essential oils in non-irradiated sample were 77.13%, and the irradiated samples at doses of 1, 3, 5, 10 and 20 kGy were 84.98%, 83.70%, 83.94%, 82.84% and 82.58%, respectively. Oxygenated terpenes such as β-eudesmol, α-eudesmol, and verbenone were increased after irradiation but did not correlate with the irradiation dose. The yields of active substances such as essential oil were increased after irradiation; however, the yields of essential oils and the irradiation dose were not correlated. Thus, the profile of composition volatiles of A. gigas Nakai did not change with irradiation

  5. The ethanolic extract of ashitaba stem (Angelica keskei [Miq.] Koidz as future antituberculosis

    Directory of Open Access Journals (Sweden)

    Sri Agung Fitri Kusuma

    2018-01-01

    Full Text Available Considering the easy contagion of tuberculosis (TB disease spread and the emergence of multidrug-resistant TB, which directly impacts the failure of therapeutic goals and mortality rates increasing, TB disease control remains to be the main concern of continuous health development effort. Therefore, the discovery of new TB drug is needed. This research assessed the new natural anti-TB drug from the ethanolic extract of Angelica keiskei stem obtained from Lombok, Indonesia. The objectives of this study were to evaluate the sensitivity of Mycobacterium tuberculosis (Mtb H37Rv strain to A. keiskei stem extract and to determine its minimum inhibitory concentration (MIC. The extraction methods of A. keiskei stem were done using a maceration method. In addition to phytochemical screening and water content analysis using standard method, the phytochemical parameters were analyzed by thin-layer chromatography. Ethanolic extract of A. keiskei stem was assayed for their Mtb inhibitory activity using the proportion method. The phytochemical analysis result showed that the secondary metabolites contain in the extract were flavonoid, polyphenol, tannin, monoterpenoid and sesquiterpen, quinon, and saponin. The anti-TB test result showed the active activity of ethanolic extract of A. keiskei against Mtb H37Rv strain with MIC ranging from 6% to 8% w/v. In conclusion, ethanolic extract of A. keiskei is a prospective natural anti-TB for the future.

  6. [Determination of four coumarin constituents before and after Angelicae Dahuricae Radix stewed with yellow rice wine and research on its mutual transformation mechanism].

    Science.gov (United States)

    Yuan, Zi-Min; Wang, Jing; Jia, Tian-Zhu; Chen, Jian-Feng

    2016-08-01

    To determine the contents of oxypeucedanin, oxypeucedanin hydrate, byakangelicol and byak-angelicin both before and after Angelicae Dahuricae Radix was stewed with yellow rice wine by high-performance liquid chromatography, and study the mutual transformation mechanisms of oxypeucedanin into oxypeucedanin hydrate, as well as byakangelicol into byak-angelicin. The research results indicated that the contents of oxypeucedanin and byakangelicol were decreased, but the contents of oxypeucedanin hydrate and byak-angelicin were increased after Angelicae Dahuricae Radix was processed with yellow rice wine. The contents' changes of these chemical compounds were due to the ring opening reaction of epoxy compounds, such as oxypeucedanin and byakangelicol under the weak acidity and heating conditions of yellow rice wine. This research could provide a scientific basis for the processing mechanism of Angelicae Dahuricae Radix with yellow rice wine stewing. Copyright© by the Chinese Pharmaceutical Association.

  7. Down-regulation of NF-κB DNA binding activity by Angelica Sinensis to ameliorate radiation-induced pulmonary injury in mouse model

    International Nuclear Information System (INIS)

    Cao Zhen; Xie Conghua; Zhou Fuxiang; Luo Zhiguo; Zhou Yunfeng; Hang Guang

    2008-01-01

    Objective: To study the trend of NF-kB binding activity during the course of radiation-induced pulmonary injury (RPI), and to evaluate the intervention effect of Angelica Sinensis on it. Methods: Adult female C57BL/6J mice were randomly divided into 4 groups: blank control group (N group), Angelica Sinensis control group (A group), irradiation group (NX group) and irradiation group with Angelica Sinensis intervention (AX group). All mice from the NX and AX groups underwent single fraction of 12 Gy γ-ray delivered to the whole thorax. All mice were intraperitoneally injected 25% Angelica Sinensis injection (20 ml/kg) or identical volume Normal Sodiumdaily injection initiated 1 week before irradiation, lasted till 2 weeks after irradiation. Mice were sacrificed at designated time points (1, 24, 72 h, 1, 2, 4, 8, 16 and 24 weeks), and the whole lungs were removed freshly. HE and Masson staining were performed to provide histopathologic evidence and to evaluate the collagen deposit situation respectively. The immunohistochemical staining of NF-κB P65 protein was performed to identify the location as well as the relative content of P65 protein. The DNA binding activity of NF-κB was detected by TransAM TM ELISA assay. Results: HE and Masson staining manifested that visible pathological alterations began at 2 weeks, typical interstitial pneumonitis were showed at 4 and 8 weeks, collagen deposition was visible from 16 weeks. The NF-κB binding activity detection and the immunohistochemical half-quantity analysis showed two-phase elevation, at 24 h and 8 weeks. Preventive application of Angelica Sinensis revealed prominently ameliorative effect for RPI, with pathological improvement, decreased immunohistochemical staining and lower NF-κB binding activity in both peaks. Conclusions: During the development process of RPI, NF-κB binding activity shows two-phase elevation. Chinese medicine Angelica Sinensis can down-regulate the elevation, showing noted ameliorative effect

  8. Identification of species and materia medica within Angelica L. (Umbelliferae) based on phylogeny inferred from DNA barcodes.

    Science.gov (United States)

    Yuan, Qing-Jun; Zhang, Bin; Jiang, Dan; Zhang, Wen-Jing; Lin, Tsai-Yun; Wang, Nian-He; Chiou, Shu-Jiau; Huang, Lu-Qi

    2015-03-01

    DNA barcodes have been increasingly used in authentication of medicinal plants, while their wide application in materia medica is limited in their accuracy due to incomplete sampling of species and absence of identification for materia medica. In this study, 95 leaf accessions of 23 species (including one variety) and materia medica of three Pharmacopoeia-recorded species of Angelica in China were collected to evaluate the effectiveness of four DNA barcodes (rbcL, matK, trnH-psbA and ITS). Our results showed that ITS provided the best discriminatory power by resolving 17 species as monophyletic lineages without shared alleles and exhibited the largest barcoding gap among the four single barcodes. The phylogenetic analysis of ITS showed that Levisticum officinale and Angelica sinensis were sister taxa, which indicates that L. officinale should be considered as a species of Angelica. The combination of ITS + rbcL + matK + trnH-psbA performed slight better discriminatory power than ITS, recovering 23 species without shared alleles and 19 species as monophyletic clades in ML tree. Authentication of materia medica using ITS revealed that the decoction pieces of A. sinensis and A. biserrata were partially adulterated with those of L. officinale, and the temperature around 80 °C processing A. dahurica decoction pieces obviously reduced the efficiency of PCR and sequencing. The examination of two cultivated varieties of A. dahurica from different localities indicated that the four DNA barcodes are inefficient for discriminating geographical authenticity of conspecific materia medica. This study provides an empirical paradigm in identification of medicinal plants and their materia medica using DNA barcodes. © 2014 The Authors. Molecular Ecology Resources Published by John Wiley & Sons Ltd.

  9. Environmental hazard mapping using GIS and AHP - A case study of Dong Trieu District in Quang Ninh Province, Vietnam

    Science.gov (United States)

    Anh, N. K.; Phonekeo, V.; My, V. C.; Duong, N. D.; Dat, P. T.

    2014-02-01

    In recent years, Vietnamese economy has been growing up rapidly and caused serious environmental quality plunging, especially in industrial and mining areas. It brings an enormous threat to a socially sustainable development and the health of human beings. Environmental quality assessment and protection are complex and dynamic processes, since it involves spatial information from multi-sector, multi-region and multi-field sources and needs complicated data processing. Therefore, an effective environmental protection information system is needed, in which considerable factors hidden in the complex relationships will become clear and visible. In this paper, the authors present the methodology which was used to generate environmental hazard maps which are applied to the integration of Analytic Hierarchy Process (AHP) and Geographical Information system (GIS). We demonstrate the results that were obtained from the study area in Dong Trieu district. This research study has contributed an overall perspective of environmental quality and identified the devastated areas where the administration urgently needs to establish an appropriate policy to improve and protect the environment.

  10. Association between grip strength and hand and knee radiographic osteoarthritis in Korean adults: Data from the Dong-gu study.

    Directory of Open Access Journals (Sweden)

    Lihui Wen

    Full Text Available We assessed whether grip strength was related to various types of radiographic damage in Korean adults with osteoarthritis (OA.Data from 2,251 subjects enrolled in the Dong-gu study, who had no hand joint pain, were analyzed to investigate the relationship between grip strength and OA. Hand grip strength was measured using a hand-held dynamometer, and radiographs of the hand and knee were scored according to a semi-quantitative grading system. Multiple linear regressions were used to explore associations between grip strength and radiographic features of OA.Grip strength in men and women was negatively related to hand (both p < 0.001 and knee (men, p < 0.001; women, p = 0.010 OA after adjusting for confounders. Hand (men, p < 0.001; women, p = 0.001 and knee (both p < 0.001 joint space narrowing (JSN showed the strongest associations with low grip strength, regardless of gender. Moreover, the severity of hand osteophytes in women (p = 0.001, and subchondral cysts (men, p < 0.001 was correlated with low grip strength in both genders.Among subjects without hand joint pain, low grip strength was associated significantly with hand and knee radiographic OA, regardless of gender. Among all types of OA radiographic damage, low grip strength showed the strongest association with JSN.

  11. Environmental hazard mapping using GIS and AHP – A case study of Dong Trieu District in Quang Ninh Province, Vietnam

    International Nuclear Information System (INIS)

    Anh, N K; Duong, N D; Phonekeo, V; My, V C; Dat, P T

    2014-01-01

    In recent years, Vietnamese economy has been growing up rapidly and caused serious environmental quality plunging, especially in industrial and mining areas. It brings an enormous threat to a socially sustainable development and the health of human beings. Environmental quality assessment and protection are complex and dynamic processes, since it involves spatial information from multi-sector, multi-region and multi-field sources and needs complicated data processing. Therefore, an effective environmental protection information system is needed, in which considerable factors hidden in the complex relationships will become clear and visible. In this paper, the authors present the methodology which was used to generate environmental hazard maps which are applied to the integration of Analytic Hierarchy Process (AHP) and Geographical Information system (GIS). We demonstrate the results that were obtained from the study area in Dong Trieu district. This research study has contributed an overall perspective of environmental quality and identified the devastated areas where the administration urgently needs to establish an appropriate policy to improve and protect the environment

  12. Optimization of induction, subculture conditions, and growth kinetics of Angelica sinensis (Oliv.) Diels callus.

    Science.gov (United States)

    Huang, Bing; Han, Lijuan; Li, Shaomei; Yan, Chunyan

    2015-01-01

    Angelica sinensis (Oliv.) Diels is an important traditional Chinese medicine, and the medicinal position is its root. This perennial herb grows vigorously only in specific areas and the environment. Tissue culture induction of callus and plant regeneration is an important and effective way to obtain large scale cultures of A. sinensis. The objective was to optimize the inductive, subculture conditions, and growth kinetics of A. sinensis. Tissue culture conditions for A. sinensis were optimized using leaves and petioles (types I and II) as explants source. Murashige and Skoog (MS) and H media supplemented with 30 g/L sucrose, 7.5 g/L agar, and varying concentrations of plant growth regulators were used for callus induction. In addition, four different basal media supplemented with 1.0 mg/L 2,4-dichlorophenoxy acetic acid (2,4-D), 0.2 mg/L 6-benzyladenine (BA) and 30 g/L sucrose were optimized for callus subculture. Finally, growth kinetics of A. sinensis cultured on different subculture media was investigated based on callus properties, including fresh weight, dry weight, medium pH, callus relative fresh weight growth, callus relative growth rate (CRGR), and sucrose content. MS medium supplemented with 5 mg/L α-naphthaleneacetic acid, 0.5 mg/L BA, 0.7 mg/L 2,4-D, 30 g/L sucrose and 7.5 g/L agar resulted in optimal callus induction in A. sinensis while petiole I was found as the best plant organ for callus induction. The B5 medium supplemented with 1.0 mg/L 2,4-D, 0.2 mg/L BA and 30 g/L sucrose displayed the best results in A. sinensis callus subculture assays. The optimized conditions could be one of the most potent methods for large-scale tissue culture of A. sinensis.

  13. Determination of coumarins in the roots of Angelica dahurica by supercritical fluid chromatography.

    Science.gov (United States)

    Pfeifer, Isabella; Murauer, Adele; Ganzera, Markus

    2016-09-10

    The fact that supercritical fluid chromatography (SFC) offers many desirable features is known for a long time. Yet, the number of applications on natural products is still limited, because robust and user-friendly instrumentation became available just a few years ago. As coumarins hardly have been studied by this technique we developed the first SFC assay for their determination in crude plant material. After method optimization eight standard compounds, including simple coumarins, linear and angular furanocoumarins, could be baseline separated in 6min using an Acquity UPC(2) CSH Fluoro-Phenyl 1.7μm column with supercritical CO2, methanol and diethylamine as mobile phase. Method validation confirmed that the assay is linear (R(2)≥0.9995), precise (intra-day variation≤5.8%; inter-day variation≤4.4%) and accurate (recovery rates from 96.5 to 104.2%). Detection limits determined at 300nm were below 2ng on-column, and the method showed to be well suited for the analysis of coumarins in Angelica dahurica roots. It was observed that qualitative as well as quantitative composition vary significantly. In all samples Imperatorin (0.09-0.28%) was the major coumarin, followed either by Isoimperatorin or Oxypeucedanin; the total coumarin content ranged from 0.16 to 0.77%. The results were in good agreement to published data, so that because of its speed and green nature SFC is definitely an interesting alternative for the analysis of this important class of natural products. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Presence of e-EDCs in surface water and effluents of pollution sources in Sai Gon and Dong Nai river basin

    Directory of Open Access Journals (Sweden)

    Tam Le Thi Minh

    2016-01-01

    Full Text Available This study aimed to assess the presence of estrogenic endocrine disrupting compounds (e-EDCs including estriol, bisphenol A (BPA, atrazine (ATZ, octylphenol, octylphenol diethoxylate, octylphenol triethoxylate, nonylphenol, Nonylphenol triethoxylate (NPE3, nonylphenol diethoxylate (NPE2 and 17β-estradiol in: (i Sai Gon and Dong Nai river waters which have been major raw water sources for drinking water supply for Ho Chi Minh City (HCMC and neighbouring provinces, and (ii water pollution sources located in their catchment basin. NPE3 and NPE2 were detected in most of the surface water samples. Concentrations of NPE3 were in a range of less than 5.9–235 ng L−1, whereas BPA was detected at significantly high concentrations in the dry season in canals in HCMC. In the upstream of Sai Gon and Dong Nai Rivers, ATZ concentrations were observed at water intake of water treatment plants served for HCMC water supply system. Similarly, high potential risk of NPE2 and NPE3 contamination at Phu Cuong Bridge near Hoa Phu water intake was identified. The significant correlation between NPE2, dissolved organic carbon and total nitrogen was found. Estrogenic equivalent or estrogenic activity of Sai Gon and Dong Nai Rivers was lower than those of the previous studies. Compared with other studies, e-EDCs of pollution in Sai Gon river basin were relatively low.

  15. Phytoestrogens: a viable option?

    Science.gov (United States)

    Russell, Lori; Hicks, G Swink; Low, Annette K; Shepherd, Jinna M; Brown, C Andrew

    2002-10-01

    Estrogen replacement therapy is one of the most commonly prescribed medicines in the United States by traditional medical professionals. Over the past decade, the market for complementary/ alternative therapies for hormone replacement has dramatically increased. Women are seeking more "natural" alternatives to treat menopausal symptoms. Well-designed randomized clinical trials are often lacking, as is the information on efficacy and safety. This article will review several popular herbal therapies for menopausal symptoms including phytoestrogens, black cohosh (Cimicifuga racemosa), dong quai (Angelica sinensis), chast tree (Vitex agnus-castus), and wild Mexican yam. Their use, mechanism of action, and adverse effects are outlined.

  16. Identification and comparative quantification of bio-active phthalides in essential oils from si-wu-tang, fo-shou-san, radix angelica and rhizoma chuanxiong.

    Science.gov (United States)

    Tang, Yuping; Zhu, Min; Yu, Sheng; Hua, Yongqing; Duan, Jin-Ao; Su, Shulan; Zhang, Xu; Lu, Yin; Ding, Anwei

    2010-01-15

    Phthalides are important bio-active constituents in Si-Wu-Tang and Fo-Shou-San, two commonly used Traditional Chinese Medicine (TCM) combined prescriptions mainly derived from Radix Angelica and Rhizoma Chuanxiong. In this paper, the contents of eight phthalides, including Z-ligustilide, E-ligustilide, Z-butylenephthalide, E-butylene-phthalide, 3-butylphthalide, neocnidilide and senkyunolide A were determined or estimated by gas chromatography-mass spectrometry (GC-MS). The results showed GC-MS was a simple, rapid, and high sensitive method for analyzing phthalides in Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong, and the extractable contents of each phthalides including Z-ligustilide, E-ligustilide, Z-butylenephthalide, etc. varied after Radix Angelica, Rhizoma Chuanxiong were combined into a formulation, such as Si-Wu-Tang and Fo-Shou-San. Furthermore, inhibition activity of essential oils from Si-Wu-Tang, Fo-Shou-San, Radix Angelica and Rhizoma Chuanxiong on uterine contraction was tested in an in vitro assay, and the results showed that the activity of the essential oil is higher as the content of the phthalides increase, which demonstrated that phthalides are possibly main active components inhibiting mice uterine contraction in vitro. All of the results suggested that comparative analysis of chemical components and pharmacological activities of each herb and formula is possibly helpful to elucidate the active components in traditional Chinese medicine, and to reveal the compatibility mechanism of TCM formulae.

  17. Changes in urinary Cu, Zn, and Se levels in cancer patients after treatment with Sha Shen Mai Men Dong Tang

    Directory of Open Access Journals (Sweden)

    Tung-Yuan Lai

    2016-04-01

    Full Text Available Sha Shen Mai Men Dong Tang (SMD-2; 沙參麥冬湯 shā shēn mài dōng tāng is a Chinese medicinal herb (CMH; 中草藥 zhōng cǎo yào used to treat symptoms associated with cancer therapy. The objective of this study was to assess the effect of SMD-2 on the levels of urinary copper (Cu, zinc (Zn, and selenium (Se in lung cancer patients and head and neck cancer patients receiving chemoradiotherapy. Forty-two head and neck cancer patients and 10 lung cancer patients participated in our clinical trial. Each patient received chemoradiotherapy for 4 weeks. In addition, each patient was treated with SMD-2 for 8 weeks, including 2 weeks prior to and after the chemoradiotherapy treatment. Comparison of urinary Cu, Zn, and Se levels and the ratios of Zn to Cu and Se to Cu at three time points in the two types of cancer were assessed using the generalized estimating equations (GEEs. After the patients received chemoradiotherapy for 4 weeks, SMD-2 treatment was found to be associated with a significant decrease in urinary Cu levels, whereas urinary Zn and Se levels increased significantly. In addition, the ratios of Zn to Cu and Se to Cu in the urine samples of these patients also increased significantly. Both the urinary Zn levels and the ratio of Zn to Cu in head and neck cancer patients were significantly higher than in lung cancer patients. Urinary Zn and Se levels and the ratios of Zn to Cu and Se to Cu, but not urinary Cu levels, increased significantly during and after treatment when assessed using the GEE model. The SMD-2 treatments significantly increased Zn and Se levels in the urine of head and neck cancer patients. Increased Zn and Se levels in urine strengthened immune system.

  18. Assessment of injection safety in Ha Dong General Hospital, Hanoi, in 2012 [version 4; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Phan Van Tuong

    2017-11-01

    Full Text Available Background: Injection is one of the most frequently used medical methods to introduce drugs or other substances into the body for purposes of treatment or prevention. Unsafe injection can cause adverse outcomes, such as abscess and anaphylactic shock, and increases the risk of blood-borne transmission of viruses to patients and health care workers, as well as the community. Recognizing the importance of injection safety, in 2000 the Vietnamese Ministry of Health (MOH collaborated with the Vietnam Nurses Association to launch the “Safe injection” program throughout the country, including Hanoi. Methods: This cross-sectional study, combining quantitative and qualitative analysis, was conducted from February to August 2012 in Ha Dong General Hospital using a structured questionnaire and observation checklist. The target population of the study was 109 nurses working in clinical departments and 436 injections were observed. Results: The percentage of nurses who are familiar with injection safety standards was found to be 82.6%. The proportion of practical injections that met the 23 standards of injection safety set by the MOH amounted to 22.2%. The factors related to safe injection practice of nurses who were younger age group (OR=3.1; p<0.05 and fewer number of years working as a nurse (OR=2.8; p<0.05. Conclusions: While nurses have high level of knowledge about safe injections but a small proportion actually practiced. Experience may not always guarantee safe practices.  Injection safety training should be regularly imparted upon all categories of nurses.

  19. Assessment of injection safety in Ha Dong General Hospital, Hanoi, in 2012 [version 3; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Phan Van Tuong

    2017-09-01

    Full Text Available Background: Injection is one of the most frequently used medical methods to introduce drugs or other substances into the body for purposes of treatment or prevention. Unsafe injection can cause adverse outcomes, such as abscess and anaphylactic shock, and increases the risk of blood-borne transmission of viruses to patients and health care workers, as well as the community. Recognizing the importance of injection safety, in 2000 the Vietnamese Ministry of Health (MOH collaborated with the Vietnam Nurses Association to launch the “Safe injection” program throughout the country, including Hanoi. Methods: This cross-sectional study, combining quantitative and qualitative analysis, was conducted from February to August 2012 in Ha Dong General Hospital using a structured questionnaire and observation checklist. The target population of the study was 109 nurses working in clinical departments and 436 injections were observed. Results: The percentage of nurses who are familiar with injection safety standards was found to be 82.6%. The proportion of practical injections that met the 23 standards of injection safety set by the MOH amounted to 22.2%. The factors related to safe injection practice of nurses who are younger age group (OR=3.1; p<0.05 and lower amount of working years (OR=2.8; p<0.05. Conclusions: Despite the high level of knowledge about safety injection, a low proportion of nurses performed correct safety injection practice. Moreover, the results demonstrated that experience might not always guarantee better practice. The findings raise the need for further training about this issue, especially among older nurses.

  20. Angelica sinensis in China-A review of botanical profile, ethnopharmacology, phytochemistry and chemical analysis.

    Science.gov (United States)

    Wei, Wen-Long; Zeng, Rui; Gu, Cai-Mei; Qu, Yan; Huang, Lin-Fang

    2016-08-22

    Angelica sinensis (Oliv.) Diels, known as Dang Gui (in Chinese), is a traditional medicinal and edible plant that has long been used for tonifying, replenishing, and invigorating blood as well as relieving pain, lubricating the intestines, and treating female irregular menstruation and amenorrhea. A. sinensis has also been used as a health product and become increasingly popular in China, Japan, and Korea. This paper aims to provide a systemic review of traditional uses of A. sinensis and its recent advances in the fields of phytochemistry, analytical methods and toxicology. In addition, possible trends, therapeutic potentials, and perspectives for future research of this plant are also briefly discussed. An extensive review of the literature was conducted, and electronic databases including China National Knowledge Infrastructure, PubMed, Google Scholar, Science Direct, and Reaxys were used to assemble the data. Ethnopharmacological literature and digitalised sources of academic libraries were also systematically searched. In addition, information was obtained from local books and The Plant List (TPL, www.theplantlist.org). This study reviews the progress in chemical analysis of A. sinensis and its preparations. Previously and newly established methods, including spectroscopy, thin-layer chromatography (TLC), gas chromatography (GC), high-performance liquid chromatography (HPLC), ultra-performance liquid chromatography(UPLC), and nuclear magnetic resonance analysis (NMR), are summarized. Moreover, identified bioactive components such as polysaccharides, ligustilide and ferulic acid were reviewed, along with analytical methods for quantitative and qualitative determination of target analytes, and fingerprinting authentication, quality evaluation of A. sinensis, and toxicology and pharmacodynamic studies. Scientific reports on crude extracts and pure compounds and formulations revealed a wide range of pharmacological activities, including anti-inflammatory activity

  1. Anti-Cancer Effect of Angelica Sinensis on Women’s Reproductive Cancer

    Directory of Open Access Journals (Sweden)

    Hong-Hong Zhu

    2012-06-01

    Full Text Available Objective: Danggui, the root of Angelica Sinensis, has traditionally been used for the treatment of women’s reproductive disorders in China for thousands of years. This study was to determine whether Danggui have potential anti-cancer effect on women’s cancer and its potential mechanism. Methods: Danggui was extracted by ethanol. The Cell Titer 96® Aqueous Non-Radioactive Cell Proliferation Assay was used to compare the effects of Danggui on human breast (MCF-7 and 7368 and cervical (CaSki and SiHa cancer cells with its effects on normal fibroblasts (HTB-125. A revised Ames test was used to test for antimutagenicity. The standard strains of Salmonella typhimarium (TA 100 and 102 were used in the test. Methyl methane sulfonate (MMS and UV light were used as positive mutagen controls and ethanol and double distilled water (DDW as controls. The SAS statistical software was used to analyze the data. Results: Danggui was found to be much more toxic to all cancer cell lines tested than to normal fibroblasts. There was a significant negative dose-effect relationship between Danggui and cancer cell viability. Average viability of MCF-7 was 69.5%, 18.4%, 5.7%, 5.7%, and 5.0% of control for Danggui doses 0.07, 0.14, 0.21, 0.32, and 0.64 ug/ul, respectively, with a Ptrend < 0.0001. Half maximal inhibitory dose (ID50 of Danggui for cancer cell lines MCF-7, CaSki, SiHa and CRL-7368 was 0.10, 0.09, 0.10 and 0.07 ug/ul, Functional Foods in Health and Disease 2012, 2(6:242-250respectively. For the normal fibroblasts, ID50 was 0.58 ug/ul. At a dose of 0.32 ug/ul, Danggui killed over 90% of the cells in each cancer cell line, but at the same dose, only 12.3 % of the normal HTB-125 cells were killed. Revertants per plate of TA 100 decreased with the introduction of increasing doses of Danggui extracts with a Ptrend < 0.0001 when UV light was used as a mutagen. There was no difference in revertants per plate between ethanol and DDW control groups. Conclusions

  2. Tao Dong | NREL

    Science.gov (United States)

    -7986 Orcid ID http://orcid.org/0000-0002-4961-7576 Research Interests Microbial biomass characterization, fractionation, and conversion Affiliated Research Programs Algal Biomass Conversion Biogas to (2015) "Regulation of Starch and Lipid Accumulation in a Microalga Chlorella Sorokiniana,"

  3. Modulation role of angelica sinensis on transforming growth factor beta 1 (TGF-β1) expression induced by radiation in the lung tissue

    International Nuclear Information System (INIS)

    Xie Conghua; Zhou Yunfeng; Peng Gang; Zhou Fuxiang; Zhang Gong; Liang Chen; Liu Hui; Chen Ji; Xia Mingtong

    2005-01-01

    Objective: To investigate the ability of Angelica Sinensis to affect the radiation- induced TGF-β 1 release in the animal model, so as to find an effective method to reduce the lung toxicity after thoracic irradiation. Methods: The thoraces of C57BL/6 mice were exposed to either sham irradiation or single fraction of 12 Gy. Four study groups were defined: those that received neither irradiation nor Angelica Sinensis (NT group), those that received Angelica Sinensis but no irradiation (AS group), those that underwent irradiation without Angelica Sinensis (XRT group) and those that received both Angelica Sinensis and irradiation (AS/XRT group). Treated and sham-irradiated control mice were sacrificed at times corresponding to the latent period (1, 24, 72 hours and 1 week postirradiation), the pneumonic phase (2, 4, 8, and 16 weeks postirradiation), and the beginning of the fibrotic phase (24 weeks postirradiation) . The TGF-β 1 mRNA expressions in the lung tissue were quantified by real-time quantitative reverse transcription polymerase chain reaction (RT-PCR). Immunohistochemical Streptavidin-Peroxidase method and positive cell counting were used for objective quantification of TGF-β 1 protein expression. Results: NT and AS groups exhibited low levels of TGF-β 1 protein expression with positive cell counts between 9 and 31. And there is an significantly elevated level of TGF-β 1 positive inflammatory cells in XRT group (P 1 in XRT group was significantly higher than the nonirradiated groups (P 1 response on mRNA level, but the statistical comparison of the TNF-αmRNA expression between the XRT and AS/XRT treatment-group was not significant (P=0.054). Conclusion: This study demonstrates a significant radiation-induced increase of TGF-β 1 (on mRNA and protein level) in the lung tissue, and the predominant localisation of TGF-β 1 in areas of inflammatory cell infiltrates suggests involvement of this cytokine in the pathogenesis of radiation-induced lung injury

  4. Biosynthesis, Characterization, and Bioactivities Evaluation of Silver and Gold Nanoparticles Mediated by the Roots of Chinese Herbal Angelica pubescens Maxim

    Science.gov (United States)

    Markus, Josua; Wang, Dandan; Kim, Yeon-Ju; Ahn, Sungeun; Mathiyalagan, Ramya; Wang, Chao; Yang, Deok Chun

    2017-01-01

    A facile synthesis and biological applications of silver (DH-AgNps) and gold nanoparticles (DH-AuNps) mediated by the aqueous extract of Angelicae Pubescentis Radix (Du Huo) are explored. Du Huo is a medicinal root belonging to Angelica pubescens Maxim which possesses anti-inflammatory, analgesic, and antioxidant properties. The absorption spectra of nanoparticles in varying root extract and metal ion concentration, pH, reaction temperatures, and time were recorded by ultraviolet-visible (UV-Vis) spectroscopy. The presence of DH-AgNps and DH-AuNps was confirmed from the surface plasmon resonance intensified at 414 and 540 nm, respectively. Field emission transmission electron micrograph (FE-TEM) analysis revealed the formation of quasi-spherical DH-AgNps and spherical icosahedral DH-AuNps. These novel DH-AgNps and DH-AuNps maintained an average crystallite size of 12.48 and 7.44 nm, respectively. The biosynthesized DH-AgNps and DH-AuNps exhibited antioxidant activity against 2,2-diphenyl-1-picrylhydrzyl (DPPH) radicals and the former exhibited antimicrobial activity against clinical pathogens including Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Salmonella enterica. The expected presence of flavonoids, sesquiterpenes, and phenols on the nanoparticle surface were conjectured to grant protection against aggregation and free radical scavenging activity. DH-AgNps and DH-AuNps were further investigated for their cytotoxic properties in RAW264.7 macrophages for their potential application as drug carriers to sites of inflammation. In conclusion, this green synthesis is favorable for the advancement of plant mediated nano-carriers in drug delivery systems, cancer diagnostic, and medical imaging.

  5. [Textual research on Guang dong xin yu (New Sayings of Guangdong) quoted in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica].

    Science.gov (United States)

    Zhang, Ruixian; Zhang, Wei; Li, Jian; Liang, Fei

    2014-05-01

    Altogether 15 terms for Guang dong xin yu (New Sayings of Guangdong) were used in Ben cao gang mu shi yi (Supplements to Compendium of Materia Medica), including Yue yu (Cantonese sayings), Chong yu (Sayings from Insect Drug), Jie yu (Sayings from Crustacean Drug), Xin yu (New Sayings), Yue hai xiang yu (Fragrant Sayings from Cantonese Region), Yue zhi mu yu (Sayings from Plants in Cantonese Annals), Guang dong suo yu (Trivial Sayings from Guangdong), Yue shan lu (Records of Cantonese Mountains), Yue lu (Cantonese Records), Jiao guang lu (Joint Guangdong Records), Yue cao zhi (Records of Cantonese Grasses), Guang guo lu (Records of Guangdong Fruits), Nan yue suo ji (Trivial Records of Southern Canton), Guang zhi (Guangdong Records), Yue zhi (Cantonese Records) etc. dealing with 57 sorts of drugs (with individual overlapping ones), the author of Xin yu was Qu Dajun, a surviving fogy of the Ming Dynasty actively involved in the activities to restore the old dynasty and resist the Qing Dynasty, and was persecuted in the literary inquisition in which his works were burnt so that Zhao Xuemin, when quoting his texts, had to go in a roundabout way.

  6. Hydrodeoxygenation of the angelica lactone dimer, a cellulose-based feedstock: simple, high-yield synthesis of branched C7 -C10 gasoline-like hydrocarbons.

    Science.gov (United States)

    Mascal, Mark; Dutta, Saikat; Gandarias, Inaki

    2014-02-10

    Dehydration of biomass-derived levulinic acid under solid acid catalysis and treatment of the resulting angelica lactone with catalytic K2 CO3 produces the angelica lactone dimer in excellent yield. This dimer serves as a novel feedstock for hydrodeoxygenation, which proceeds under relatively mild conditions with a combination of oxophilic metal and noble metal catalysts to yield branched C7 -C10 hydrocarbons in the gasoline volatility range. Considering that levulinic acid is available in >80 % conversion from raw biomass, a field-to-tank yield of drop-in, cellulosic gasoline of >60 % is possible. Copyright © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Correlation between synergistic action of Radix Angelica dahurica extracts on analgesic effects of Corydalis alkaloid and plasma concentration of dl-THP.

    Science.gov (United States)

    Liao, Zheng-Gen; Liang, Xin-Li; Zhu, Jing-Yun; Zhao, Guo-Wei; Yang, Ming; Wang, Guang-Fa; Jiang, Qie-Ying; Chen, Xu-Long

    2010-05-04

    Yuanhu Zhitong prescription that consists of Corydalis yanhusuo and Radix Angelicae dahuricae has been used for the treatment of gastralgia, costalgia, headache and dysmenorrhea in Traditional Chinese Medicine. Our previous studies demonstrated that Corydalis alkaloid (CA, derived from the root of Corydalis yanhusu) had potent analgesic properties, and the total coumarins of Angelica dahurica (Cou) and volatile oil (VO) that derived from the root of Radix Angelicae dahuricae all could increase the analgesic effect of CA. The major objective of this paper was to investigate the mechanism that leading the analgesia of CA increased by Cou and (or) VO. The relationship between analgesic effect of CA and the plasma concentration of Dl-tetrahydropalmatine (dl-THP, active component of CA) was assayed in mice writhing test. The CA (34, 68 and 134 mg/kg) reduced the nociception by acetic acid intraperitoneal injection in a dose-dependent manner, and there was a significant linear relationship between the analgesic effect of CA and the plasma concentration of dl-THP. Then the plasma concentration of dl-THP at different time intervals in rats after oral administration of CA, CA-Cou, CA-VO and CA-Cou-VO were examined by using HPLC. The results indicated that Cou and (or) VO raised the plasma concentration of dl-THP prominently. In conclusion, the reason that Radix Angelica dahurica extracts reinforced the analgesic effects of Corydalis alkaloid was related to the improvement of the plasma concentration of dl-THP. (c) 2010 Elsevier Ireland Ltd. All rights reserved.

  8. Anti-Inflammatory Effects of Angelica sinensis (Oliv. Diels Water Extract on RAW 264.7 Induced with Lipopolysaccharide

    Directory of Open Access Journals (Sweden)

    Young-Jin Kim

    2018-05-01

    Full Text Available The dry root of Angelica sinensis (Oliv. Diels, also known as “female ginseng”, is a popular herbal drug amongst women, used to treat a variety of health issues and cardiovascular diseases. The aim of this study is to evaluate the detailed molecular mechanism for anti-inflammatory effects of Angelica sinensis root water extract (ASW. The anti-inflammatory effect of ASW on lipopolysaccharide (LPS-induced RAW 264.7 mouse macrophages was evaluated by the tetrazolium-based colorimetric assay (MTT, Griess reagent assay, multiplex cytokine assay, real time reverse transcription polymerase chain reaction (RT-PCR, and Fluo-4 calcium assay. ASW restored cell viability in RAW 264.7 at concentrations of up to 200 µg/mL. ASW showed notable anti-inflammatory effects. ASW exhibited IC50 = 954.3, 387.3, 191.7, 317.8, 1267.0, 347.0, 110.1, 573.6, 1171.0, 732.6, 980.8, 125.0, and 257.0 µg/mL for interleukin (IL-6, tumor necrosis factor (TNF-α, monocyte chemotactic activating factor (MCP-1, regulated on activation, normal T cell expressed and secreted (RANTES, granulocyte colony-stimulating factor (G-CSF, granulocyte macrophage colony-stimulating factor (GM-CSF, vascular endothelial growth factor (VEGF, lipopolysaccharide-induced CXC chemokine (LIX, macrophage inflammatory protein (MIP-1α, MIP-1β, MIP-2, IL-10, and intracellular calcium, respectively. Additionally, ASW inhibited the LPS-induced production of nitric oxide and the LPS-induced mRNA expression of CHOP (GADD153, Janus kinase 2 (JAK2, signal transducers and activators of transcription 1 (STAT1, first apoptosis signal receptor (FAS, and c-Fos, NOS2, and PTGS2 (COX2 in RAW 264.7 significantly (p < 0.05. Data suggest that ASW exerts an anti-inflammatory effect on LPS-induced RAW 264.7 via NO-bursting/calcium-mediated JAK-STAT pathway.

  9. Inhibition of PAI-1 release from human endothelial cells by Angelica keiskei Koidzumi (Ashitaba chalcones is structure-dependent

    Directory of Open Access Journals (Sweden)

    Naoki Ohkura

    2015-12-01

    Full Text Available Angelica keiskei Koidzumi (Ashitaba is a traditional herbal medicine and it is also regarded in Japan as a health food that might have antithrombotic properties. Ashitaba exudate suppresses lipopolysaccharide (LPS-induced plasma plasminogen activator inhibitor 1 (PAI-1, a risk factor for thrombotic diseases in mice. Xanthoangelol (XA and 4-hydroxyderricin (4-HD comprise > 95% of total chalcones from Ashitaba exudates that also contain trace amounts of other chalcone subtypes. The present study aimed to determine the effects of Ashitaba chalcones including xanthoangelols B (XB, D (XD, E (XE, F (XF and XA as well as 4-HD on PAI-1 levels in the medium of stimulated human EA.hy926 endothelial cells. Xanthoangelol (10 and #61549;M inhibited PAI-1 production at a rate of 77.1%, whereas the inhibition rates of XB, XD, XE and 4-HD were not significant. Xanthoangelol F was highly cytotoxic and thus its ability to inhibit PAI-1 production could not be evaluated. The side hydrocarbon chain of XA played an important role in the excretion of inhibitory activity. Small modifications of the hydrocarbon chain or small functional groups on the A ring measurably influenced the inhibitory activity of xanthoangelols. These findings warrant future research towards an understanding of the mechanism of antithrombotic action of Ashitaba as herbal medicine or antithrombotic health food. [J Intercult Ethnopharmacol 2015; 4(4.000: 355-357

  10. Effect of polysaccharides from Angelica sinensis on Bcl-2 and Bax protein expression of irradiated liver cells

    International Nuclear Information System (INIS)

    Sun Yuanlin; Tang Jian; Gu Xiaohong; Li Deyuan

    2009-01-01

    Objective: To investigate the effect of polysaccharides from Angelica sinensis (ASP3) on Bcl-2 and Bax protein expression of irradiated liver cells from mice. Methods: Bcl-2 and Bax protein expression of liver cells in vitro exposed to 2.0 Gy rays were examined by using immunohistochemistry method. Results: The expression of apoptosis-accelerating protein Bax in the irradiation group was enhanced obviously (70.83%), while apoptosis inhibiting protein Bcl-2 tended to decline (55.60%), with the statistically significant difference (P <0.01) compared with that of the control. ASP3 pretreatment could regulate Bcl-2 and Bax protein expression of liver cells, inhibiting Bax protein expression(64.14/58.37%) and increasing Bcl-2 protein expression(59.21%/ 67.45%). The differences between the high dosage (100 mg/L of ASP3) and the irradiation group were statistically significant (P<0.05). Conclusions: ASP3 pretreatment could prohibit the apoptosis of radiation- damaged liver cells due to abnormal expression of Bcl-2 and Bax, and reduce the cell apoptosis by increasing Bcl-2/Bax protein expression so as to enhance the radiation endurance of liver cells. (authors)

  11. The Methanol Extract of Angelica sinensis Induces Cell Apoptosis and Suppresses Tumor Growth in Human Malignant Brain Tumors

    Directory of Open Access Journals (Sweden)

    Yu-Ling Lin

    2013-01-01

    Full Text Available Glioblastoma multiforme (GBM is a highly vascularized and invasive neoplasm. The methanol extract of Angelica sinensis (AS-M is commonly used in traditional Chinese medicine to treat several diseases, such as gastric mucosal damage, hepatic injury, menopausal symptoms, and chronic glomerulonephritis. AS-M also displays potency in suppressing the growth of malignant brain tumor cells. The growth suppression of malignant brain tumor cells by AS-M results from cell cycle arrest and apoptosis. AS-M upregulates expression of cyclin kinase inhibitors, including p16, to decrease the phosphorylation of Rb proteins, resulting in arrest at the G0-G1 phase. The expression of the p53 protein is increased by AS-M and correlates with activation of apoptosis-associated proteins. Therefore, the apoptosis of cancer cells induced by AS-M may be triggered through the p53 pathway. In in vivo studies, AS-M not only suppresses the growth of human malignant brain tumors but also significantly prolongs patient survival. In addition, AS-M has potent anticancer effects involving cell cycle arrest, apoptosis, and antiangiogenesis. The in vitro and in vivo anticancer effects of AS-M indicate that this extract warrants further investigation and potential development as a new antibrain tumor agent, providing new hope for the chemotherapy of malignant brain cancer.

  12. [Structural analysis and anti-tumor activity in vivo of polysaccharide APS-2a from Angelica sinensis].

    Science.gov (United States)

    Cao, Wei; Li, Xiao-Qiang; Hou, Ying; Fan, Hui-Ting; Zhang, Xiao-Nan; Mei, Qi-Bing

    2008-02-01

    The polysaccharide APS-2a was isolated from Angelica sinensis (Oliv.) Diels through water extraction, deprotein, ethanol precipitation and DEAE-sephades A-25 column chromatography respectively,and was further purified by Sephacryl S-400 and Sephadex G-100 column chromatography. The phenol-sulfuric acid assay and Bradford method were used to determine the contents of carbohydrate and protein, respectively. The molecular weight was carried out with high-performance size exclusion chromatography (HPSEC) combined with a differential refractometer detector. The monosaccharide compositions were determined by gas chromatography after complete hydrolysis with acid. The models of mice transplanted sarcoma S-180 were used to study the anti-tumor effects in vivo. Thymus indexes, spleen indexes were determined. The HPSEC result showed the APS-2a was a single homogeneous component and its weight average molecular weight was 7.4 x 10(5) Da. The monosaccharide composition of APS-2a was glucose, galactose, arabinose, rhamnose, galcturonic acid. Furthermore, APS-2a (20.50 mg/kg) could inhibit the proliferation of tumor cells in mice transplanted S-180. The thymus indexes and spleen indexes in the groups treated with APS-2a were higher than control group.

  13. Study on Angelica and its different extracts by Fourier transform infrared spectroscopy and two-dimensional correlation IR spectroscopy

    Science.gov (United States)

    Liu, Hong-xia; Sun, Su-qin; Lv, Guang-hua; Chan, Kelvin K. C.

    2006-05-01

    In order to develop a rapid and effective analysis method for studying integrally the main constituents in the medicinal materials and their extracts, discriminating the extracts from different extraction process, comparing the categories of chemical constituents in the different extracts and monitoring the qualities of medicinal materials, we applied Fourier transform infrared spectroscopy (FT-IR) associated with second derivative infrared spectroscopy and two-dimensional correlation infrared spectroscopy (2D-IR) to study the main constituents in traditional Chinese medicine Angelica and its different extracts (extracted by petroleum ether, ethanol and water in turn). The findings indicated that FT-IR spectrum can provide many holistic variation rules of chemical constituents. Use of the macroscopical fingerprint characters of FT-IR and 2D-IR spectrum can not only identify the main chemical constituents in medicinal materials and their different extracts, but also compare the components differences among the similar samples. This analytical method is highly rapid, effective, visual and accurate for pharmaceutical research.

  14. A Systematic Review of the Mysterious Caterpillar Fungus Ophiocordyceps sinensis in Dong-ChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo) and Related Bioactive Ingredients

    Science.gov (United States)

    Lo, Hui-Chen; Hsieh, Chienyan; Lin, Fang-Yi; Hsu, Tai-Hao

    2013-01-01

    The caterpillar fungus Ophiocordyceps sinensis (syn.† Cordyceps sinensis), which was originally used in traditional Tibetan and Chinese medicine, is called either “yartsa gunbu” or “DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo)” (“winter worm-summer grass”), respectively. The extremely high price of DongChongXiaCao, approximately USD $20,000 to 40,000 per kg, has led to it being regarded as “soft gold” in China. The multi-fungi hypothesis has been proposed for DongChongXiaCao; however, Hirsutella sinensis is the anamorph of O. sinensis. In Chinese, the meaning of “DongChongXiaCao” is different for O. sinensis, Cordyceps spp.,‡ and Cordyceps spƒ. Over 30 bioactivities, such as immunomodulatory, antitumor, anti-inflammatory, and antioxidant activities, have been reported for wild DongChongXiaCao and for the mycelia and culture supernatants of O. sinensis. These bioactivities derive from over 20 bioactive ingredients, mainly extracellular polysaccharides, intracellular polysaccharides, cordycepin, adenosine, mannitol, and sterols. Other bioactive components have been found as well, including two peptides (cordymin and myriocin), melanin, lovastatin, γ-aminobutyric acid, and cordysinins. Recently, the bioactivities of O. sinensis were described, and they include antiarteriosclerosis, antidepression, and antiosteoporosis activities, photoprotection, prevention and treatment of bowel injury, promotion of endurance capacity, and learning-memory improvement. H. sinensis has the ability to accelerate leukocyte recovery, stimulate lymphocyte proliferation, antidiabetes, and improve kidney injury. Starting January 1st, 2013, regulation will dictate that one fungus can only have one name, which will end the system of using separate names for anamorphs. The anamorph name “H. sinensis” has changed by the International Code of Nomenclature for algae, fungi, and plants to O. sinensis. PMID:24716152

  15. A Systematic Review of the Mysterious Caterpillar Fungus Ophiocordyceps sinensis in DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo and Related Bioactive Ingredients

    Directory of Open Access Journals (Sweden)

    Hui-Chen Lo

    2013-01-01

    Full Text Available The caterpillar fungus Ophiocordyceps sinensis (syn.† Cordyceps sinensis, which was originally used in traditional Tibetan and Chinese medicine, is called either “yartsa gunbu” or “DongChongXiaCao (冬蟲夏草 Dōng Chóng Xià Cǎo” (“winter worm-summer grass”, respectively. The extremely high price of DongChongXiaCao, approximately USD $20,000 to 40,000 per kg, has led to it being regarded as “soft gold” in China. The multi-fungi hypothesis has been proposed for DongChongXiaCao; however, Hirsutella sinensis is the anamorph of O. sinensis. In Chinese, the meaning of “DongChongXiaCao” is different for O. sinensis, Cordyceps spp.,‡ and Cordyceps spƒ. Over 30 bioactivities, such as immunomodulatory, antitumor, anti-inflammatory, and antioxidant activities, have been reported for wild DongChongXiaCao and for the mycelia and culture supernatants of O. sinensis. These bioactivities derive from over 20 bioactive ingredients, mainly extracellular polysaccharides, intracellular polysaccharides, cordycepin, adenosine, mannitol, and sterols. Other bioactive components have been found as well, including two peptides (cordymin and myriocin, melanin, lovastatin, γ-aminobutyric acid, and cordysinins. Recently, the bioactivities of O. sinensis were described, and they include antiarteriosclerosis, antidepression, and antiosteoporosis activities, photoprotection, prevention and treatment of bowel injury, promotion of endurance capacity, and learning-memory improvement. H. sinensis has the ability to accelerate leukocyte recovery, stimulate lymphocyte proliferation, antidiabetes, and improve kidney injury. Starting January 1st, 2013, regulation will dictate that one fungus can only have one name, which will end the system of using separate names for anamorphs. The anamorph name “H. sinensis” has changed by the International Code of Nomenclature for algae, fungi, and plants to O. sinensis.

  16. What factors affect the quality of life of patients with keloids? Quais fatores realmente afetam a qualidade de vida dos portadores de queloide?

    Directory of Open Access Journals (Sweden)

    Fabianne Furtado

    2009-01-01

    Full Text Available OBJECTIVE: To evaluate factors that affect the quality of life (QoL of patients with keloids. METHODS: A study was conducted on 102 patients of both genders between 15 and 70 years old. During initial evaluation, clinical factors, such as keloid visibility, duration and evolution of the disease, previous treatments, types of treatments and recurrence were recorded. Later, patients responded to the QualiFibro questionnaire, which is specific for evaluation of the QoL of patients with keloids and comprises the physical and psychological domains, and six visual numeric scales (VNS, of which three are related to psychological factors (satisfaction with appearance, shame of the disease, and suffering experienced, and the other three are related to physical factors (pruritus, pain and movement restriction. RESULTS: Patients with keloids on non-visible areas of the body (pOBJETIVO: Avaliar quais fatores influenciam a qualidade da vida (QV dos portadores de quelóide. MÉTODOS: Estudo envolvendo 102 pacientes, de ambos os gêneros, com idade entre 15 e 70 anos. Na avaliação inicial, os fatores clínicos referentes à visibilidade do queloide, tempo de evolução da doença, tratamento prévio, tipos de tratamento e recidiva foram catalogados. Posteriormente, os pacientes responderam ao questionário QualiFibro, composto pelos domínios físico e psicológico, específico para avaliar a QV dos portadores de quelóide, e a seis escalas visuais numéricas (EVN, sendo três escalas em relação a fatores psicológico (satisfação com a aparência, vergonha da doença e sofrimento vivenciado, e três escalas em relação a fatores físicos (prurido, dor e restrição de movimentos. RESULTADOS: A pontuação do domínio físico do questionário QualiFibro foi maior para os portadores de queloide em região não-visível (p<0,01 e com tempo de evolução maior que 10 anos (p<0,049, refletindo piora em relação aos portadores com queloide em região vis

  17. A randomized, double-blind, placebo- controlled study on the anti-haemostatic effects of Curcuma longa, Angelica sinensis and Panax ginseng.

    Science.gov (United States)

    Fung, Foon Yin; Wong, Wan Hui; Ang, Seng Kok; Koh, Hwee Ling; Kun, Mei Ching; Lee, Lai Heng; Li, Xiaomei; Ng, Heng Joo; Tan, Chuen Wen; Zhao, Yan; Linn, Yeh Ching

    2017-08-15

    Herbs with "blood-activating" properties by traditional medicine theory often raise concerns for their possible anti-platelet or anticoagulation effects based on reports from in vitro studies. Such herbs have been implicated for bleeding manifestations based on only anecdotal reports. In particular, the combination of such herbs with anti-platelet agents is often empirically advised against despite lack of good clinical evidence. Here we studied 3 commonly used herbal preparations Curcuma longa, Angelica sinensis and Panax ginseng on their respective anti-platelet and anticoagulation effect, alone and in combination with aspirin. This is a randomized, double-blind, placebo-controlled trial involving 25 healthy volunteers for each herbal preparation. Each subject underwent 3 phases comprising of herbal product alone, aspirin alone and aspirin with herbal product, where each phase lasted for 3 weeks with 2 weeks of washout between phases. PT/APTT, platelet function by light transmission aggregometry and thrombin generation assay by calibrated automated thrombogram were measured at baseline and after each phase. Information on adverse reaction including bleeding manifestations was collected after each phase. On the whole there was no clinically relevant impact on platelet and coagulation function. With the exception of 5 of 24 subjects in the Curcuma longa group, 2 of 24 subjects in the Angelica sinensis group and 1 of 23 subjects in the Panax ginseng group who had an inhibition in arachidonic-acid induced platelet aggregation, there was no effect of these 3 herbals products on platelet aggregation by other agonists. Combination of these herbal products with aspirin respectively did not further aggravate platelet inhibition caused by aspirin. None of the herbs impaired PT/APTT or thrombin generation. There was no significant bleeding manifestation. This study on healthy volunteers provides good evidence on the lack of bleeding risks of Curcuma longa, Angelica sinensis

  18. [Experimental study on aging effect of Angelica sinensis polysaccharides combined with cytarabine on human leukemia KG1alpha cell lines].

    Science.gov (United States)

    Xu, Chun-Yan; Geng, Shan; Liu, Jun; Zhu, Jia-Hong; Zhang, Xian-Ping; Jiang, Rong; Wang, Ya-Ping

    2014-04-01

    The latest findings of our laboratory showed that Angelica sinensis polysaccharide (ASP) showed a definite effect in regulating the aging of hematopoietic stem cells. Leukemia is a type of malignant hematopoietic tumor in hematopoietic stem cells. There have been no relevant reports about ASP's effect in regulating the aging of leukemia cells. In this study, human acute myeloid leukemia (AML) KG1alpha cell lines in logarithmic growth phase were taken as the study object, and were divided into the ASP group, the cytarabine (Ara-C) group, the ASP + Ara-C group and the control group. The groups were respectively treated with different concentration of ASP, Ara-C and ASP + Ara-C for different periods, with the aim to study the effect of ASP combined with Ara-C in regulating the aging of human acute myeloid leukemia KG1alpha cell lines and its relevant mechanism. The results showed that ASP, Ara-C and ASP + Ara-C could obviously inhibit KG1alpha cell proliferation in vitro, block the cells in G0/G1 phase. The cells showed the aging morphological feature. The percentage of positive stained aging cells was dramatically increased, and could significantly up-regulate the expression of aging-related proteins P16 and RB, which were more obvious in the ASP + Ara-C group. In conclusion, the aging mechanism of KG1alpha cell induced by ASP and Ara-C may be related to the regulation of the expression of aging-related proteins, suggesting that the combined administration of ASP and anticancer drugs plays a better role in the treatment of leukemia .

  19. The Effects of Angelica Sinensis Polysaccharide on Tumor Growth and Iron Metabolism by Regulating Hepcidin in Tumor-Bearing Mice

    Directory of Open Access Journals (Sweden)

    Feng Ren

    2018-05-01

    Full Text Available Background/Aims: Iron plays a fundamental role in cell biology and its concentration must be precisely regulated. It is well documented that excess iron burden contributes to the occurrence and progression of cancer. Hepcidin secreted by liver plays an essential role in orchestrating iron metabolism. In the present study, we aimed to investigate the ability of angelica sinensis polysaccharide (ASP to decrease iron burden in tumor-bearing mice and the mechanism of ASP regulation hepcidin expression. Methods: Western blot, RT-PCR, immunohistochemistry (IHC, and enzyme-linked immunosorbent assay (ELISA were used to detect the regulation of hepcidin and related cytokines by ASP. The role of ASP in tumor proliferation was investigated using in vivo assays. Iron depositions and iron concentrations in organs were determined by hematoxylin-eosin (H&E staining and atomic absorption spectrophotometer. Results: We found that ASP could inhibit tumor growth in mice xenografted with 4T1 and H22 cancer cells. In vivo experiments also showed that ASP could potently regulate hepcidin expression in liver and serum and decrease iron burden in liver, spleen and grafted tumors in mouse model. Treatment with ASP in hepatic cell lines reproduced comparable results in decreasing hepcidin as in mouse liver. Furthermore, we found that ASP markedly suppressed the expression of interleukin-6 (IL-6, JAK2, p-STAT3, and p-SMAD1/5/8 in liver, suggesting that JAK/STAT and BMP-SMAD pathways were involved in the regulation of hepcidin expression by ASP. We also found down-regulation of iron-related cytokines in ASP treated mice. Conclusion: The present study provides new evidence that ASP decreases hepcidin expression, which can reduce iron burden and inhibit tumor proliferation. These findings might aid ASP developed as a potential candidate for cancer treatment in patients with iron overload.

  20. Angelica sinensis (Oliv.) Diels: Influence of Value Chain on Quality Criteria and Marker Compounds Ferulic Acid and Z-Ligustilide.

    Science.gov (United States)

    Giacomelli, Nino; Yongping, Yang; Huber, Franz K; Ankli, Anita; Weckerle, Caroline S

    2017-03-14

    Background: Dang gui (Apiaceae; Angelica sinensis radix) is among the most often used Chinese medicinal plants. However, hardly anything is known about its value chain and its influence on the main marker compounds of the drug. The aim of this study is to investigate the value chain of dang gui in Gansu and Yunnan, and the analysis of the marker compounds ferulic acid and Z-ligustilide concentration in relation to quality criteria such as the production area and size of the roots. Methods: During six months of field research in China, semi-structured interviews with various stakeholders of the value chain were undertaken and plant material was collected. High-performance thin layer chromatography (HPTLC) was used for semi-quantitative analysis of ferulic acid and Z-ligustilide. Results: Small-scale household cultivation prevails and in Gansu-in contrast to Yunnan-the cultivation of dang gui is often the main income source of farmers. Farmers and dealers use size and odor of the root as main quality criteria. For Chinese medicine doctors, Gansu as the production area is the main criterion. Higher amounts of ferulic acid in plant material from Yunnan compared to Gansu were found. Additionally, a negative relation of root length with both ferulic acid and Z-ligustilide as well as head diameter with ferulic acid were found. Conclusions: HPTLC is a valid method for semi-quantitative analysis of the marker compounds of dang gui . However, the two main marker compounds cannot explain why size and smell of the root or production area are seen as quality criteria. This hints at the inherent difficulty to correlate quality notions of medicinal plants with specific chemical compounds. With respect to this, more attention should be paid to quality in terms of cultivation and processing techniques.

  1. Research on Chemical Composition and Biological Properties Including Antiquorum Sensing Activity of Angelica pancicii Vandas Aerial Parts and Roots.

    Science.gov (United States)

    Mileski, Ksenija S; Trifunović, Snežana S; Ćirić, Ana D; Šakić, Željana M; Ristić, Mihailo S; Todorović, Nina M; Matevski, Vlado S; Marin, Petar D; Tešević, Vele V; Džamić, Ana M

    2017-12-20

    The essential oil, different extracts, and isolated compounds of Angelica pancicii Vandas (Apiaceae) were investigated for the first time. The GC-FID and GC-MS analyses revealed sesquiterpenoids as the main constituents of A. pancicii essential oil of aerial parts with bornyl acetate (8.08%), n-octanol (5.82%), kessane (4.26%), and β-selinene (4.26%) as the main constituents. Analysis of methanol extracts, using an HPLC-DAD/ESI-ToF-MS system, showed a total of 52 compounds in the aerial parts and 53 in the roots, indicating coumarins as the main constituents. In addition, new chromone (1) and six known furanocoumarins (2-7) were isolated from the roots and structurally elucidated by combined spectroscopic methods. The aerial part extracts exhibited higher polyphenolic contents and antioxidant activity evaluated by three radical scavenging assays. Using a microwell dilution method, the strongest antibacterial activity profiles were determined for ethanol and methanol root extracts (minimum bactericidal concentrations (MBCs) = 0.25-3.00 mg/mL), which were comparable to the activity of streptomycin (MBCs = 0.34-1.24 mg/mL), while the strongest antibacterial compound of A. pancicii was oxypeucedanin hydrate (MBCs = 0.50-8.00 mg/mL). Antifungal potential was in moderate extent, and the highest activity was obtained for root methanol extract (minimum fungicidal concentrations (MFCs) = 4.00-14.00 mg/mL). Tested sub-minimum inhibitory concentrations (subMICs) of the extracts and isolated compounds inhibited selected Pseudomonas aeruginosa PAO1 virulence determinants. The most reduced growth of P. aeruginosa colony was in the presence of isolated oxypeucedanin. Ethanol (17.36-46.98%) and methanol (34.54-52.43%) root extracts showed higher anti-biofilm activity compared to streptomycin (49.40-88.36%) and ampicillin (56.46-92.16%).

  2. A Importância da participação dos pais na creche e no jardim de infância : quais os obstáculos à participação dos pais

    OpenAIRE

    Carvalho, Marta Silvestre

    2016-01-01

    Relatório apresentado para a obtenção do grau de mestre em Educação pré-escolar O presente trabalho “ A Importância da Participação dos Pais na Creche e no Jardim-de-infância: Quais os Obstáculos à Participação dos Pais”, aborda a promoção do envolvimento e a participação dos pais na vida escolar das crianças, como os pais ou encarregados de educação consideram a importância da promoção da participação da família, bem como a satisfação da sua participação e quais os obstáculos encontrados....

  3. Quantitative Analysis of Ca, Mg, and K in the Roots of Angelica pubescens f. biserrata by Laser-Induced Breakdown Spectroscopy Combined with Artificial Neural Networks

    Science.gov (United States)

    Wang, J.; Shi, M.; Zheng, P.; Xue, Sh.; Peng, R.

    2018-03-01

    Laser-induced breakdown spectroscopy has been applied for the quantitative analysis of Ca, Mg, and K in the roots of Angelica pubescens Maxim. f. biserrata Shan et Yuan used in traditional Chinese medicine. Ca II 317.993 nm, Mg I 517.268 nm, and K I 769.896 nm spectral lines have been chosen to set up calibration models for the analysis using the external standard and artificial neural network methods. The linear correlation coefficients of the predicted concentrations versus the standard concentrations of six samples determined by the artificial neural network method are 0.9896, 0.9945, and 0.9911 for Ca, Mg, and K, respectively, which are better than for the external standard method. The artificial neural network method also gives better performance comparing with the external standard method for the average and maximum relative errors, average relative standard deviations, and most maximum relative standard deviations of the predicted concentrations of Ca, Mg, and K in the six samples. Finally, it is proved that the artificial neural network method gives better performance compared to the external standard method for the quantitative analysis of Ca, Mg, and K in the roots of Angelica pubescens.

  4. [Effects and mechanism of Angelicae Sinensis Radix on Th1/Th2 and Th17/Treg in mice with asthma and Yin deficiency syndrome].

    Science.gov (United States)

    Ma, Ting-Ting; Feng, Xing-Zhong; Wang, Xue-Yan

    2017-02-01

    Angelicae Sinensis Radix, with nourishing Yin, promoting blood circulation, and moisturizing dryness functions, is commonly used in clinical medicine. In order to investigate the effects and mechanism of Angelica sinensis(AS) on Th1/Th2 and Th17/Treg in mice with asthma and Yin deficiency syndrome, asthmatic and Yin deficiency syndrome Balb/c mice models were established by injecting and inhaling ovalbumin(OVA) and thyroxin. The models were treated with dexamethasone(DXM), AS extract and AS extract+DXM, respectively. Pathological examination of lung tissues was conducted by HE staining, and ELISA was used to detect the levels of IL-4, IL-17, IFN-γ, TGF-β as well as retinoic acid receptor-related orphan receptor (RORγt). Results showed that AS could significantly improve the situation of inflammation infiltration, increase ratios of IFN-γ/IL-4 and TGF-β/IL-17, decrease the levels of RORγt in lung tissues. The AS+DXM group showed a best treatment effect. The results indicated that AS played a therapeutic role for asthma with Yin deficiency syndrome and improved airway inflammation by inhibiting the expression of RORγt in lung tissues and regulating the balance of Th1/Th2 and Th17/Treg. Copyright© by the Chinese Pharmaceutical Association.

  5. cDNA-AFLP analysis of gene expression differences between the flower bud and sprout-shoot apical meristem of Angelica sinensis (Oliv. Diels

    Directory of Open Access Journals (Sweden)

    Yu Guang

    2011-01-01

    Full Text Available Angelica sinensis (Oliv. Diels (Umbelliferae is a well-known medicinal plant mainly distributed in Gansu Province of China. Its local and global demand is significant because of its food and medicinal applications. However, the early bolting rate of Angelica sinensis (Oliv. Diels reaches 20%-60%, which seriously affects its food and medicinal qualities. Thus, differences in gene expression between the flower bud and sprout-shoot apical meristem underwent analysis, by means of cDNA-amplified restriction fragment length polymorphism, to better understand the flowering mechanism. 64 primer sets, each of which amplified to 60 transcript-derived fragments (TDFs, were used. Among these TDFs, 26 were expressed specifically in the flower bud. After cloning and sequencing, 32 distinct sequences were obtained from these 26 TDFs, and 25 were found with homologous sequences in databases. Confirmation of differential expression of 13 sequences was obtained by semi-quantitative RT-PCR, their showing higher expression levels in flower buds. These homologous sequences encode transposable elements, pentatricopeptide repeat-containing proteins, DNA-binding transcription factors, zinc finger (B-box type family proteins, NADP-dependent sorbitol 6-phosphate dehydrogenase (S6PDH, amongst others.

  6. The determinants of long-term care utilization and equity of access to care among older adults in Dong-Ku of Incheon Metropolitan city, South Korea.

    Science.gov (United States)

    Park, J M

    2005-01-01

    Under the current health care system, around three percent of the elderly remain uninsured. Based on the 2003 Dong-Ku Health Status Survey and the Aday and Andersen Access Framework, the present study examined the social and behavioral determinants of long-term care utilization and the extent to which equity in the use of long-term care services for the elderly has been achieved. The results indicate that universal health insurance system has not yielded a fully equitable distribution of services. Type of coverage and resource availability do not remain predictors of long-term care utilization. The data suggest that a universal health insurance system exists in South Korea with significant access problems for the population without insurance. Access differences also arise from obstacles in expanding the scope and level of plan benefits due to financial disparity among insurers. Health policy reforms must continue to concentrate on extending insurance coverage to the uninsured and establishing long-term insurance system for the elderly.

  7. Effect of “Jian-Pi-Zhi-Dong Decoction” on Gamma-Aminobutyric Acid in a Mouse Model of Tourette Syndrome

    Directory of Open Access Journals (Sweden)

    Wen Zhang

    2014-01-01

    Full Text Available The purpose of this study was to explore the positive effects of Jian-Pi-Zhi-Dong Decoction (JPZDD on Tourette syndrome (TS by investigating the expression of gamma-aminobutyric acid (GABA and its type A receptor (GABAAR in the striatum of a TS mice model. The model was induced by 3,3′-iminodipropionitrile (IDPN treatment; then mice were divided into 4 groups (n=22, each; control and IDPN groups were gavaged with saline and the remaining 2 groups were gavaged with tiapride and JPZDD. We recorded the stereotypic behaviors of TS mice and measured the content of GABA in striatum by HPLC and GABAAR expression by immunohistochemistry and real-time PCR. Our results showed that JPZDD inhibited the abnormal behaviors of TS model mice and decreased GABA levels and GABAAR protein and mRNA expression in the striatum of TS model mice. In brief, the mechanism by which JPZDD alleviates TS symptoms may be associated with GABAAR expression downregulation in striatum which may regulate GABA metabolism.

  8. Qi-Dong-Huo-Xue-Yin Inhibits Inflammation in Acute Lung Injury in Mice via Toll-Like Receptor 4/Caveolin-1 Signaling

    Directory of Open Access Journals (Sweden)

    Li-Ying Xu

    2018-01-01

    Full Text Available Acute lung injury (ALI is a critical illness with no current effective treatment. Caveolin-1 indirectly activates inflammation-associated signaling pathways by inhibiting endothelial nitric oxide synthase (eNOS. This induces an imbalance between pro- and anti-inflammatory cytokine levels, which are involved in the pathogenesis of ALI. The compound Chinese prescription Qi-Dong-Huo-Xue-Yin (QDHXY is efficacious for ALI treatment via an anti-inflammatory effect; however, the exact underlying mechanism is unknown. Therefore, we explored the protective effect of QDHXY against lipopolysaccharide- (LPS- induced ALI in mice. Histopathological changes in mouse lung tissues were studied. Furthermore, alterations in the serum levels of pro- and anti-inflammatory cytokines were investigated. The levels of tumor necrosis factor- (TNF-α, interleukin- (IL- 6, IL-1β, and interferon-γ-induced protein 10 in bronchoalveolar lavage fluid were measured. Additionally, the expression levels of myeloid differentiation factor 88 (MyD88, caveolin-1, and eNOS were assessed. QDHXY significantly reduced lung infiltration with inflammatory cells and the production of serum pro- and anti-inflammatory cytokines and inhibited the expression of TNF-α, IL-1β, caveolin-1, and MyD88 but not eNOS. These indicate that QDHXY significantly improved the balance between pro- and anti-inflammatory cytokine levels, possibly by inhibiting the caveolin-1 signaling pathway. Therefore, QDHXY may be a potential treatment for ALI.

  9. Livelihoods and Land Uses in Environmental Policy Approaches: The Case of PES and REDD+ in the Lam Dong Province of Vietnam

    Directory of Open Access Journals (Sweden)

    Leif Tore Trædal

    2017-02-01

    Full Text Available This paper explores assumptions about the drivers of forest cover change in a Payments for Environmental Services (PES and Reduced Emissions from Deforestation and Degradation (REDD+ context in the Lam Dong Province in Vietnam. In policy discourses, deforestation is often linked to ‘poor’ and ‘ethnic minority’ households and their unsustainable practices such as the expansion of coffee production (and other agricultural activities into forest areas. This paper applies a livelihood framework to discuss the links between livelihoods and land use amongst small-scale farmers in two communities. The findings of the livelihood survey demonstrate no clear linkages between poverty levels and unsustainable practices. In fact, the poorest segments were found to deforest the least. The ways in which current PES and REDD+ approaches are designed, do not provide appropriate solutions to address the underlying dimensions of issues at stake. The paper criticizes one-dimensional perspectives of the drivers behind deforestation and forest degradation often found in public policies and discourses. We suggest more comprehensive analyses of underlying factors encompassing the entire coffee production and land use system in this region. Addressing issues of land tenure and the scarcity of productive lands, and generating viable off-farm income alternatives seem to be crucial. Sustainable approaches for reducing deforestation and degradation could be possible through engaging with multiple stakeholders, including the business-oriented households in control of the coffee trade and of land transactions.

  10. Social Functions of Ritual Music of Dong Funeral Ceremony%侗族丧葬仪式音乐的社会功能探析--以黔东南黎平县龙额村为例

    Institute of Scientific and Technical Information of China (English)

    姚仕秀

    2014-01-01

    侗族丧葬仪式是侗族人民的一项重要人生仪礼,它的内容和形式与侗族人民的宗教信仰观念有着密切关系,反映了侗族社会的民间传统习俗文化。仪式音乐作为丧葬仪式的组成部分,在仪式过程中担负着不同类型的角色,有赞颂亡者功德、沟通人神对话等媒介的作用。解读龙额侗族丧葬仪式音乐文化,分析其文化内涵及社会功能,对了解和研究侗族丧葬仪式特征,具有重要的价值和意义。%The funeral ceremony of Dong is an important ritual for Dong people. There is a close relationship between its religious concepts and its form and content, reflecting the traditional customs and culture of Dong. As a part of the funeral ceremony, the ritual music plays a different type of roles in it:praising the dead, and communicating with God, and so on. This paper studies the culture of its funeral music and analyzes its cultural conno-tations and social functions for better understanding characteristics of the Dong funeral ceremony, which has important value and significance.

  11. Angelica sinensis (Umbelliferae) with proven repellent properties against Aedes aegypti, the primary dengue fever vector in Thailand.

    Science.gov (United States)

    Champakaew, D; Junkum, A; Chaithong, U; Jitpakdi, A; Riyong, D; Sanghong, R; Intirach, J; Muangmoon, R; Chansang, A; Tuetun, B; Pitasawat, B

    2015-06-01

    Botanical resources with great diversity in medicinal and aromatic plants are a rich and reliable source for finding insect repellents of plant origin, which are widely popular among today's consumers. Although some herbal-based repellents have been proven comparable to or even better than synthetics, commercially available natural repellents generally tend to be expensive, with short-lived effectiveness. This critical flaw leads to ongoing research for new and effective repellents, which provide longer protection against vector and nuisance-biting insects, while remaining safe, user friendly, and reasonably priced. This study aimed to evaluate the repellent activity of plant-derived products against the primary dengue vector, Aedes aegypti, by following the human bait technique of World Health Organization guidelines. Preliminary laboratory screening tests for repellency of 33 plant species clearly demonstrated Angelica sinensis as the most effective repellent from each kind of extracted product, with its essential oil and ethanolic extract having median complete protection times of 7.0 h (6.0-7.5) and 2.5 h (2.0-2.5), respectively. Due to its low yield (0.02 %), pungent smell, and little cause of irritation, A. sinensis essential oil did not qualify as a candidate for further repellent assessment. However, subsequent extractions of A. sinensis with different organic solvents of increasing polarity provided four extractants with varying degrees of repellency against A. aegypti. The hexane extract of A. sinensis provided excellent repellency, with a median complete protection time of 7.5 h (6.5-8.5), which was longer than that of ethanol (2.5, 2.0-2.5 h), acetone (1.75, 0.5-2.5 h), and methanol extracts (0.5, 0-1.0 h). By being the most effective product, A. sinensis hexane extract gave significant protection comparable to that of its essential oil and the standard synthetic repellent, N,N-diethyl-3-methylbenzamide (DEET: 6.25, 5.0-6.5 h). Qualitative gas

  12. Le corps numérique des données The Digital Body of Data: the Transfer of Artefact Fact Sheets from the Museum of Man to the Musée du quai Branly

    Directory of Open Access Journals (Sweden)

    Tiziana Nicoletta Beltrame

    2012-05-01

    Full Text Available Le transfert des collections extra-européennes du musée de l’Homme au musée du quai Branly implique le déplacement des informations documentaires sur les objets. Des différentes fiches en papier (de collection ou d’inventaire, descriptive de l’objet, méthodique créées et classées au sein des départements du musée de l’Homme, on passe à la fiche informatique « TMS objets » au musée du quai Branly. L’information ne change pas simplement de place et de matière, elle est reconfigurée dans de nouvelles articulations du savoir sur les collections. L’inventaire muséal est ici conçu comme le système qui matérialise un savoir structuré. Pour pouvoir analyser ce système, il faut mettre en relation les propriétés des documents et les modalités de leur classement dans un espace créé ad hoc. La matérialité des supports, les multiples possibilités de rangements et de création de liens (la mise en relations entre rubriques de la fiche informatique agissent sur le contenu des données et ouvrent ainsi de nouvelles voies pour la construction du savoir.The transfer of extra-European collections from the Museum of Man to the Musée du quai Branly involves the displacement of documentary information on the artefacts. The various paper files (on collections or inventory, descriptive of the object, methodological created and classified within different departments of the Museum of Man are being replaced by digital files, or “TMS objects”, at the Musée du quai Branly. The information is not simply changing its location and material, it is being reconfigured within new interconnections of knowledge on the collections. The museum inventory is here conceived as the system that materialises a structured knowledge. To be able to analyse this system, it is necessary to link the documents’ properties to the methods used to classify them in an ad hoc space. The materiality of the media, the multiple possibilities for

  13. Quais (imposturas intelectuais? O erro de Darwin

    Directory of Open Access Journals (Sweden)

    Pascal Mettens

    Full Text Available Neste texto busca-se uma teorização do sujeito a partir da psicanálise, do estruturalismo e da noção de pós-modernidade. Os autores propõem-se, aqui, a mostrar como e por que um ocultamento da questão do sujeito incessantemente retorna e conduz às piores derivações ideológicas, diluída que é e em um corpo cujo espírito se vê reduzido a uma função entre outras ou na massa de indivíduos orientados para um fim comum, eventualmente conflitual. E tomam como hipótese “demonstrar que toda disciplina projeta sobre a maneira em que se desenvolve ‘sua’ ciência a epistemologia implícita com a qual freqüentemente se sustenta à sua revela”.

  14. Effect of Jian-Pi-Zhi-Dong Decoction on striatal glutamate and γ-aminobutyric acid levels detected using microdialysis in a rat model of Tourette syndrome

    Directory of Open Access Journals (Sweden)

    Zhang W

    2016-05-01

    Full Text Available Wen Zhang,1,* Li Wei,2,* Wenjing Yu,1 Xia Cui,1 Xiaofang Liu,2 Qian Wang,1 Sumei Wang2 1Department of Pediatrics, The Third Affiliated Hospital, 2Department of Pediatrics, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing, People’s Republic of China *These authors contributed equally to this work Background: Jian-Pi-Zhi-Dong Decoction (JPZDD is a dedicated treatment of Tourette syndrome (TS. The balance of neurotransmitters in the cortico-striato-pallido-thalamo-cortical network is crucial to the occurrence of TS and related to its severity. This study evaluated the effect of JPZDD on glutamate (Glu and γ-aminobutyric acid (GABA and their receptors in a TS rat model.Materials and methods: Rats were divided into four groups (n=12 each. TS was induced in three of the groups by injecting them with 3,3'-iminodipropionitrile for 7 consecutive days. Two model groups were treated with tiapride (Tia or JPZDD, while the control and the remaining model group were gavaged with saline. Behavior was assessed by stereotypic score and autonomic activity. Striatal Glu and GABA contents were detected using microdialysis. Expressions of N-methyl-D-aspartate receptor 1 and GABAA receptor (GABAAR were observed using Western blot and real-time polymerase chain reaction.Results: Tia and JPZDD groups had decreased stereotypy compared with model rats; however, the JPZDD group showed a larger decrease in stereotypy than the Tia group at a 4-week time point. In a spontaneous activity test, the total distance of the JPZDD and Tia groups was significantly decreased compared with the model group. The Glu levels of the model group were higher than the control group and decreased with Tia or JPZDD treatment. The GABA level was higher in the model group than the control group. Expressions of GABAAR protein in the model group were higher than in the control group. Treatment with Tia or JPZDD reduced the expression of GABAAR protein. In the case of the m

  15. Simultaneous Determination of Decursin, Decursinol Angelate, Nodakenin, and Decursinol of Angelica gigas Nakai in Human Plasma by UHPLC-MS/MS: Application to Pharmacokinetic Study

    Directory of Open Access Journals (Sweden)

    Sook-Jin Kim

    2018-04-01

    Full Text Available Coumarins in Cham-dang-gwi, the dried root of Angelica gigas Nakai (AGN, possess pharmacological effects on anemia, pain, infection, and articular rheumatism. The AGN root containes decursin (D, decursinol angelate (DA, nodakenin, and decursinol (DOH, a major metabolite of D and DA. The aim of this study was to develop a simultaneous determination method for these four coumarins in human plasma using ultra high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS. Chromatographic separation was performed on dual columns (Kinetex® C18 column and Capcell core C18 column with mobile phase consisting of water and acetonitrile at a flow rate of 0.3 mL/min using gradient elution. Multiple reaction monitoring was operated in positive ion mode with precursors to product ion transition values of m/z 328.9→228.8, 328.9→228.9, 409.4→248.8, and 246.8→212.9 to measure D, DA, nodakenin, and DOH, respectively. Linear calibration curves were fitted over concentration range of 0.05–50 ng/mL for these four components, with correlation coefficient greater than 0.995. Inter- and intra-day accuracies were between 90.60% and 108.24%. These precisions were within 11.19% for all components. The established method was then applied to a pharmacokinetic study for the four coumarins after usual dosing in Korean subjects.

  16. Polysaccharide from Angelica sinensis protects H9c2 cells against oxidative injury and endoplasmic reticulum stress by activating the ATF6 pathway.

    Science.gov (United States)

    Niu, Xiaowei; Zhang, Jingjing; Ling, Chun; Bai, Ming; Peng, Yu; Sun, Shaobo; Li, Yingdong; Zhang, Zheng

    2018-01-01

    Objectives Angelica sinensis exerts various pharmacological effects, such as antioxidant and anti-apoptotic activity. This study aimed to investigate the active ingredients in A. sinensis with antioxidant properties and whether A. sinensis polysaccharide (ASP) protects H9c2 cells against oxidative and endoplasmic reticulum (ER) stress. Methods The ingredients of A. sinensis and their targets and related pathways were determined using web-based databases. Markers of oxidative stress, cell viability, apoptosis, and ER stress-related signalling pathways were measured in H9c2 cells treated with hydrogen peroxide (H 2 O 2 ) and ASP. Results The ingredient-pathway-disease network showed that A. sinensis exerted protective effects against oxidative injury through its various active ingredients on regulation of multiple pathways. Subsequent experiments showed that ASP pretreatment significantly decreased H 2 O 2 -induced cytotoxicity and apoptosis in H9c2 cells. ASP pretreatment inhibited H 2 O 2 -induced reactive oxygen species generation, lactic dehydrogenase release, and malondialdehyde production. ASP exerted beneficial effects by inducing activating transcription factor 6 (ATF6) and increasing ATF6 target protein levels, which in turn attenuated ER stress and increased antioxidant activity. Conclusions Our findings indicate that ASP, a major water-soluble component of A. sinensis, exerts protective effects against H 2 O 2 -induced injury in H9c2 cells by activating the ATF6 pathway, thus ameliorating ER and oxidative stress.

  17. The Antidepressant Effect of Angelica sinensis Extracts on Chronic Unpredictable Mild Stress-Induced Depression Is Mediated via the Upregulation of the BDNF Signaling Pathway in Rats

    Directory of Open Access Journals (Sweden)

    Jun Shen

    2016-01-01

    Full Text Available Angelica sinensis (AS, a traditional Chinese herbal medicine, has pharmaceutical effects on menstrual illness, cerebrovascular diseases, cardiovascular diseases, and cognitive impairments. However, until recently, few studies had explored its antidepressant effect. The current study attempts to investigate the effect of AS extracts on chronic unpredictable mild stress- (CUMS- induced depression in rats. Male SD rats were exposed to a CUMS-inducing procedure for 5 weeks, resulting in rodent depressive behaviors that included reduced sucrose consumption and lessened sucrose preference ratios in sucrose preference test, prolonged immobility times and decreased struggling time in force swim test, and decreased locomotor activity in open field test. Moreover, the expression of brain derived neurotrophic factor (BDNF and the phosphorylation of cAMP-response element binding protein (CREB and extracellular signal-regulated protein kinase (ERK 1/2 were markedly decreased in the hippocampus in depressed rats. However, chronically treating the depressed rats with AS (1 g/kg normalized their depression-related behaviors and molecular profiles. In conclusion, in the present study, we show that AS extracts exerted antidepressant effects that were mediated by the BDNF signaling pathway: in AS-treated depressed rats, the expression of the BDNF protein and the phosphorylation of its downstream targets (ERK 1/2, CREB were upregulated in the hippocampus.

  18. Distribution Assessments of Coumarins from Angelicae Pubescentis Radix in Rat Cerebrospinal Fluid and Brain by Liquid Chromatography Tandem Mass Spectrometry Analysis

    Directory of Open Access Journals (Sweden)

    Yan-Fang Yang

    2018-01-01

    Full Text Available Angelicae Pubescentis Radix (APR is a widely-used traditional Chinese medicine. Pharmacological studies have begun to probe its biological activities on neurological disorders recently. To assess the brain penetration and distribution of APR, a validated ultra-performance liquid chromatography tandem mass spectrometry method was applied to the simultaneous determinations of the main coumarins from APR in the rat cerebrospinal fluid (CSF and brain after oral administration of APR extract, including psoralen, xanthotoxin, bergapten, isoimperatorin, columbianetin, columbianetin acetate, columbianadin, oxypeucedanin hydrate, angelol B, osthole, meranzin hydrate and nodakenetin. Most of the tested coumarins entered the rat CSF and brain quickly, and double-peak phenomena in concentration-time curves were similar to those of their plasma pharmacokinetics. Columbianetin had the highest concentration in the CSF and brain, while psoralen and columbianetin acetate had the largest percent of CSF/plasma and brain/plasma, indicating that these three coumarins may be worthy of further research on the possible nervous effects. Correlations between the in vivo brain distributions and plasma pharmacokinetics of these coumarins were well verified. These results provided valuable information for the overall in vivo brain distribution characteristics of APR and also for its further studies on the active substances for the central nervous system.

  19. Distribution Assessments of Coumarins from Angelicae Pubescentis Radix in Rat Cerebrospinal Fluid and Brain by Liquid Chromatography Tandem Mass Spectrometry Analysis.

    Science.gov (United States)

    Yang, Yan-Fang; Zhang, Lei; Yang, Xiu-Wei

    2018-01-20

    Angelicae Pubescentis Radix (APR) is a widely-used traditional Chinese medicine. Pharmacological studies have begun to probe its biological activities on neurological disorders recently. To assess the brain penetration and distribution of APR, a validated ultra-performance liquid chromatography tandem mass spectrometry method was applied to the simultaneous determinations of the main coumarins from APR in the rat cerebrospinal fluid (CSF) and brain after oral administration of APR extract, including psoralen, xanthotoxin, bergapten, isoimperatorin, columbianetin, columbianetin acetate, columbianadin, oxypeucedanin hydrate, angelol B, osthole, meranzin hydrate and nodakenetin. Most of the tested coumarins entered the rat CSF and brain quickly, and double-peak phenomena in concentration-time curves were similar to those of their plasma pharmacokinetics. Columbianetin had the highest concentration in the CSF and brain, while psoralen and columbianetin acetate had the largest percent of CSF/plasma and brain/plasma, indicating that these three coumarins may be worthy of further research on the possible nervous effects. Correlations between the in vivo brain distributions and plasma pharmacokinetics of these coumarins were well verified. These results provided valuable information for the overall in vivo brain distribution characteristics of APR and also for its further studies on the active substances for the central nervous system.

  20. Avaliação dos níveis de pressão sonora aos quais músicos de uma banda estão expostos

    Directory of Open Access Journals (Sweden)

    Marcio Henrique Mendes

    2009-06-01

    Full Text Available Este artigo apresenta os resultados e as discussões sobre as medidas dos níveis de pressão sonora aos quais músicos estão expostos em sua jornada de trabalho. O objeto de estudo é uma banda, estilo rock-pop, composta por cinco integrantes. O método utilizado para as medições dos níveis de ruído consistiu na avaliação dos níveis de pressão sonora por meio de um medidor de nível de pressão sonora. As medidas foram feitas em dias diferentes e em dois locais: no ambiente usado para ensaios e em uma casa de shows destinada a apresentações. Foi constatado que os níveis a que os músicos analisados foram expostos estão acima dos limites das normas vigentes. Os resultados mostraram que é possível minimizar os valores de pressão sonora por meio de medidas simples, como o uso de equipamento de proteção individual e correções inerentes à acústica ambiental.

  1. Anti-anxiety activity of successive extracts of Angelica archangelica Linn. on the elevated T-maze and forced swimming tests in rats.

    Science.gov (United States)

    Kumar, Dinesh; Bhat, Zulfiqar Ali; Shah, M Y

    2012-09-01

    Angelica archangelica Linn. is widely used in food and liquor preparations and also in Kashmiri folk medicine to reduce anxiety. We evaluated the anxiolytic effect of successive extracts of A. archangelica linn. (SAE) on rats tested in the elevated T-maze test (an animal model of generalized anxiety) at doses that exhibit antidepressant-like activity in humans. A. archangelica (1 kg) was subjected to successive extraction in a soxhlet apparatus with solvents [petroleum ether (40-60 degrees C), chloroform, ethyl acetate, methanol and decoction with water] in order of increasing polarity (yield: 6.9%, 7.3%, 5.1%, 11.88% and 8.2% w/w, respectively). SAE were evaluated for anxiolytic effects using the elevated T-maze and forced swimming tests in rats. Oral dosing of diazepam (1 mg/kg) and extracts (50, 100 and 200 mg/kg) clearly showed an anxiolytic-like profile in the elevated T-maze test: it increased one-way escape and decreased inhibitory avoidance on the first, third and seventh day. In the forced swimming test, imipramine and SAE showed antidepressant- and anxiolytic-like effects as reflected by increased climbing time, swimming time and decreased immobility time on the first, third and seventh day. Aqueous and methanol extracts showed the most, petroleum ether (40-60 degrees C) and chloroform intermediate, and ethyl acetate the least anxiolytic activity (*P<0.05, **P<0.01, ***P< 0.001) in both models. These results suggest the anti-anxiety activity of various extracts of A. archangelica and strongly justify its use in traditional Indian medicine for the treatment of anxiety.

  2. Role of Bone Morphogenetic Proteins-7 (BMP-7 in the Renal Improvement Effect of DangGui (Angelica sinensis in Type-1 Diabetic Rats

    Directory of Open Access Journals (Sweden)

    Ching-Hua Yeh

    2011-01-01

    Full Text Available Hyperglycemia induced reactive oxygen species (ROS generation is believed as major factors leading to diabetic nephropathy (DN. DangGui (Angelica sinensis is mentioned to show renal protective effect in combination with other herbs. Bone morphogenetic proteins-7 (BMP-7 is produced merit in protection of DN. The role of BMP-7 in DangGui-induced renal improvement is not clear. The present study investigated the effects of DangGui on renal functions, BMP-7 expression and the levels of ROS in streptozotocin (STZ-induced diabetic rats and high glucose-exposed rat mesangial cells (RMCs. After 1- or 4-week treatment, DangGui improved renal functions and increased renal BMP-7 expression in diabetic rats. The BMP-7 expression in RMCs was reduced by high glucose treatment and this could be reversed by DangGui. Moreover, RMCs exposed to high glucose were expired by BMP-7 RNAi transfection but those cells remained alive by scramble transfection. Thus, we employed regular RMCs to knock down BMP-7 with RNAi and we found that DangGui increased BMP-7 expression in these RMCs. Direct activation of BMP-7 expression by DangGui could be considered. The results of DPPH assay, DHE stain and lucigenin assay indicated that DangGui could inhibit high glucose-induced ROS in RMCs. These results suggest that DangGui has an ability to improve renal functions in STZ-diabetic rats through increasing endogenous BMP-7 expression and decreasing oxidative stress in kidney. The present study suggest that DangGui could be applied to improve renal functions in diabetic disorders.

  3. Síndromes do núcleo rubro. A propósito de três casos com etiologia sifilítica, um dos quais associado a mioclonias velofaringolaríngeas

    Directory of Open Access Journals (Sweden)

    Adherbal Tolosa

    1950-09-01

    Full Text Available Registrando três casos de síndromes do núcleo rubro — dois de síndrome superior e um de síndrome inferior, tipo Claude — os autores revêem a anátomo-fisiologia dessa formação mesencefálica. Ressaltam particularmente as alterações do tono verificadas pela lesão experimental do núcleo vermelho. A destruição da porção parvicelular, superior (neorrubro determina o aparecimento de hipotonia, por liberação da atividade inibidora do tono da porção magnocelular, inferior ( paleorrubro ; a lesão desta última provoca hipertonia, devido à liberação dos núcleos tonígenos romben cefálicos. Os autores, no sentido de correlacionar os fatos experimentais e anátomo-clínicos, lembram o conceito de De Giacomo sôbre a topografia das lesões nas síndromes rúbricas: na de Benedikt, o processo patológico se situaria no paleorrubro, enquanto que, na de Claude e na superior, o neorrubro seria a porção afetada.Os autores discutem também o problema das hipercinesias, destacando o caráter intencional das mesmas; lembram a existência de conexões rubrocorticais recíprocas, diretas e indiretas, e ressaltam o fato de que o núcleo de Stilling é uma estação obrigatória do circuito ideado por Bucy para explicar a fisiopatologia do tremor intencional. Os autores assinalam a raridade das síndromes rúbricas, das quais encontraram o registro de 5 casos na literatura brasileira, sendo que 4 se referemà síndrome de Benedikt. Comentando seus casos, os autores salientam os seguintes pontos: a a etiologia luética das lesões, em um caso do tipo mesenquimal e, em dois. do tipo parenquimatoso; b a existência de acentuada hipotonia em dois casos e de normalidade do tono no outro; c a normalidade do eletrencefalograma em um caso de síndrome superior do núcleo rubro e em um caso de síndrome de Claude; d a desarmonia das reações vestibulares observada em um dos casos; e a existência de distúrbios da regulação térmica no caso 2

  4. Situation of the Kinh poor and minority women and their use of the Maternal Care and Family Planning Service in Nam Dong Mountainous District, Thuathien-Hue Province, Vietnam.

    Science.gov (United States)

    Vo Van, T; Hoat, L N; Jan van Schie, T

    2004-01-01

    This study aimed to determine the barriers to the use of maternal care and family planning (MCFP) services by the disadvantaged Kinh people and Katu ethnic minority people in the remote and mountainous area of Nam Dong District in Central Vietnam. A survey was conducted using a random sample of 420 mothers with at least one child under the age of 5 years. These data were supplemented by interviews with key informants, focus group discussions and observations. Many barriers were identified. The difficulty of the terrain made travel to healthcare centers difficult. The cost of treatment was a barrier for the poorest people. The quality of the services and facilities, as well as the management of these services was perceived to be unsatisfactory. Traditional practices were often described as being contrary to the doctor's advice, and were presented as the reason for unsafe and unassisted home deliveries. Communication was difficult because of the minority languages of the client groups, the prevalence of illiteracy, and the absence of mass communication in this region. Finally, consulting a male healthcare worker was reported to bring the women shame. There is an urgent need for the MCFP services to build both clinical capacity and health promotion activities in a way that is gender sensitive, cognisant of traditional practices and accessible by both illiterate and minority language speaking people.

  5. Analysis and identification of two similar traditional Chinese medicines by using a three-stage infrared spectroscopy: Ligusticum chuanxiong, Angelica sinensis and their different extracts

    Science.gov (United States)

    Xiang, Li; Wang, Jingjuan; Zhang, Guijun; Rong, Lixin; Wu, Haozhong; Sun, Suqin; Guo, Yizhen; Yang, Yanfang; Lu, Lina; Qu, Lei

    2016-11-01

    Rhizoma Chuanxiong (CX) and Radix Angelica sinensis (DG) are very important Traditional Chinese Medicine (TCM) and usually used in clinic. They both are from the Umbelliferae family, and have almost similar chemical constituents with each other. It is complicated, time-consuming and laborious to discriminate them by using the chromatographic methods such as high performance liquid chromatography (HPLC) and gas chromatography (GC). Therefore, to find a fast, applicable and effective identification method for two herbs is urged in quality research of TCM. In this paper, by using a three-stage infrared spectroscopy (Fourier transform infrared spectroscopy (FT-IR), the second derivative infrared spectroscopy (SD-IR) and two-dimensional correlation infrared spectroscopy (2D-IR)), we analyzed and discriminated CX, DG and their different extracts (aqueous extract, alcoholic extract and petroleum ether extract). In FT-IR, all the CX and DG samples' spectra seemed similar, but they had their own unique macroscopic fingerprints to identify. Through comparing with the spectra of sucrose and the similarity calculation, we found the content of sucrose in DG raw materials was higher than in CX raw materials. The significant differences in alcoholic extract appeared that in CX alcoholic extract, the peaks at 1743 cm-1 was obviously stronger than the peak at same position in DG alcoholic extract. Besides in petroleum ether extract, we concluded CX contained much more ligustilide than DG by the similarity calculation. With the function of SD-IR, some tiny differences were amplified and overlapped peaks were also unfolded in FT-IR. In the range of 1100-1175 cm-1, there were six peaks in the SD-IR spectra of DG and the intensity, shape and location of those six peaks were similar to that of sucrose, while only two peaks could be observed in that of CX and those two peaks were totally different from sucrose in shape and relative intensity. This result was consistent with that of the

  6. Observation des influences du changement du couvert forestier sur le comportement hydrologique de grands bassins versants tropicaux a l'aide de la teledetection numerique: Cas du bassin versant de Dong Nai, Viet Nam

    Science.gov (United States)

    Pham, Trinh Hung

    Monitoring hydrological behavior of a large tropical watershed following a forest cover variation has an important role in water resource management planning as well as for forest sustainable management. Traditional methods in forest hydrology studies are Experimental watersheds, Upstream-downstream, Experimental plots, Statistical regional analysis and Watershed simulation. Those methodes have limitations for large watersheds concerning the monitoring time, the lack of input data especially about forest cover and the capacity of extrapolating results accurately in terms of large watersheds. Moreover, there is still currently a scientific debate in forest ecology on relation between water and forest. The reason of this problem comes from geographical differences in publication concerning study zones, experimental watershed size and applied methods. It gives differences in the conclusions on the influence of tropical forest cover change on the changes of outlet water and yet on the yearly runoff in terms of large watershed. In order to exceed the limitations of actual methods, to solve the difficulty of acquiring forest cover data and to have a better understanding of the relation between tropical forest cover change and hydrological behavior evolution of a large watershed, it is necessary to develop a new approach by using numeric remote sensing. We used the watershed of Dong Nai as a case study. Results show that a fusion between TM and ETM+ Landsat image series and hydro-meteorologic data allow us to observe and detect flooding trends and flooding peaks after an intensive forest cover change from 16% to 20%. Flooding frequency and flooding peaks have clearly decreased when there is an increase of the forest cover from 1983 to 1990. The influence of tropical forest cover on the hydrological behavior is varying with geographical locations of watershed. There is a significant relation between forest cover evolution and environmental facteurs as the runoff

  7. The Lao Dong Party of North Vietnam

    Science.gov (United States)

    1960-06-17

    and consol- idation of the cooperative movement and with the achievement of the task of reforming democracy in the mountain regions. .. . During the...that, on the overall picture of the enlarged cooperative movement , we must continue to improve the degree of enlightenment about socialism of the

  8. DONG JIE Zhang, LIANG Wang, ZHON

    Indian Academy of Sciences (India)

    User

    development, hairless nude skin, and short life (Abitbol et al., 2015; Bryson et al., 2013). On the ... Foxn1 maintains TECs to support T-cell development via mcm2 ... were ligated upstream of the firefly luciferase gene in the plasmid pGL3-Basic.

  9. Atividade e vulnerabilidade: quais os arranjos familiares em risco?

    Directory of Open Access Journals (Sweden)

    Lena Lavinas

    Full Text Available Dans cet article, on cherche à comparer des modèles différents de familles, selon la typologie proposée par l'IBGE, afin de vérifier si les familles dont le chef est une femme constituent en effet l'organisation familiale la plus vulnérable et en péril. C'est une idée courante qui justifie le tableau de féminisation de la pauvreté, si connu dans les vingt dernières années avec des impacts considérables sur les politiques sociales de lutte contre la pauvreté. Dans cette étude, on dégage des données sur les activités - taux d'occupation, salaire moyen, nombre d'heures de travail - non seulement par sexe, identifiant les différences homme-femme, mais on discrimine aussi les femmes entre elles, faisant un parallèle entre celles qui sont chef de famille et celles qui vivent avec leur conjoint. On observe que la vie en couple est plus nuisible à la pleine insertion de la femme sur le marché de travail que les effets même de la maternité (présence des enfants.

  10. Les sans-abris des quais d’Austerlitz

    Directory of Open Access Journals (Sweden)

    Guillaume Lannerée

    2008-03-01

    Full Text Available Les pratiques spatiales des « sans domicile fixe » sont méconnues : nous avons donc tenté, en les interrogeant, d’amorcer une réflexion sur leur spatialité qui s’apparente à un combat perpétuel. Contraints à la mobilité par des expulsions à répétition, la sédentarité gouverne néanmoins leur mode de vie. Ce phénomène s’est accentué avec les tentes qui contribuent à la visibilité des SDF aux yeux de la société. Par la restauration de leur visibilité et donc de leur spatialité, les SDF s’échappent un moment de ce nulle part dans lequel il est si tentant de les exiler.The homeless' spatial practices are not well-known: that's why we tried, relying on several interviews, to study their spatiality which is similar to a perpetual fight. Forced to move by frequent explusions, yet their way of life is sedentary. This sedentarity has been increased by the use of tents which contribute to the homeless visibility in society. Through restoration of their visibility and of their spatiality, the homeless escape for a while from this "nowhere" where one easily banishes them.

  11. Simultaneous determination of umbelliferone and scopoletin in Tibetan medicine Saussurea laniceps and traditional Chinese medicine Radix angelicae pubescentis using excitation-emission matrix fluorescence coupled with second-order calibration method

    Science.gov (United States)

    Wang, Li; Wu, Hai-Long; Yin, Xiao-Li; Hu, Yong; Gu, Hui-Wen; Yu, Ru-Qin

    2017-01-01

    A chemometrics-assisted excitation-emission matrix (EEM) fluorescence method is presented for simultaneous determination of umbelliferone and scopoletin in Tibetan medicine Saussurea laniceps (SL) and traditional Chinese medicine Radix angelicae pubescentis (RAP). Using the strategy of combining EEM fluorescence data with second-order calibration method based on the alternating trilinear decomposition (ATLD) algorithm, the simultaneous quantification of umbelliferone and scopoletin in the two different complex systems was achieved successfully, even in the presence of potential interferents. The pretreatment is simple due to the "second-order advantage" and the use of "mathematical separation" instead of awkward "physical or chemical separation". Satisfactory results have been achieved with the limits of detection (LODs) of umbelliferone and scopoletin being 0.06 ng mL- 1 and 0.16 ng mL- 1, respectively. The average spike recoveries of umbelliferone and scopoletin are 98.8 ± 4.3% and 102.5 ± 3.3%, respectively. Besides, HPLC-DAD method was used to further validate the presented strategy, and t-test indicates that prediction results of the two methods have no significant differences. Satisfactory experimental results imply that our method is fast, low-cost and sensitive when compared with HPLC-DAD method.

  12. A novel approach using metabolomics coupled with hematological and biochemical parameters to explain the enriching-blood effect and mechanism of unprocessed Angelica sinensis and its 4 kinds of processed products.

    Science.gov (United States)

    Ji, Peng; Wei, Yanming; Hua, Yongli; Zhang, Xiaosong; Yao, Wanling; Ma, Qi; Yuan, Ziwen; Wen, Yanqiao; Yang, Chaoxue

    2018-01-30

    Angelica sinensis (AS), root of Angelica sinensis (Oliv.) Diels, an important kind of Chinese traditional herbal medicine, has been used for women to enrich the blood for thousands of years. It is mainly distributed in Gansu province of China. According to Traditional Chinese medicine usage, unprocessed AS (UAS) and its 4 kinds of processed products (ASs) are all used to treat different diseases or syndromes. The difference among the enriching-blood effects of ASs is unclear. And their exact mechanisms of enriching the blood are not fully understood. In this study, our aim is to compare the enriching-blood effect and explain the related mechanism of ASs, to lay the foundation for the blood deficiency diagnosis and the rational use of ASs in the clinic. ASs were used to intervene the blood deficiency syndrome model mice induced by acetyl phenylhydrazine (APH) and cyclophosphamide (CTX). A novel approach using metabolomics coupled with hematological and biochemical parameters to explain the enriching-blood effect and mechanism of ASs was established. The blood routine examination, ATPase, glucose-6-phosphate dehydrogenase, methemoglobin, glutathion peroxidase, glutathione reductase, and erythropoietin were measured. Two biofluids (plasma and urine) obtained from mice were analyzed with GC-MS. Distinct changes in metabolite patterns of the two biofluids after mice were induced by APH and CTX, and mice were intervened with ASs were analyzed using partial least squares-discriminant analysis. Potential biomarkers were found using a novel method including variable importance in the projection (VIP) >1.0, volcano plot analysis, and significance analysis of microarray. The results of hematological, biochemical parameters and the integrated metabolomics all showed the blood deficiency syndrome model was built successfully, ASs exhibited different degree of enriching-blood effect, and AS pached with alcohol (AAS) exhibited the best enriching-blood effect. 16 metabolites in

  13. High-performance liquid chromatographic method for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma.

    Science.gov (United States)

    Xie, Ying; Chen, Yi; Lin, Mei; Wen, Jun; Fan, Guorong; Wu, Yutian

    2007-05-09

    A high-performance liquid chromatographic method was developed and validated for the determination and pharmacokinetic study of oxypeucedanin hydrate and byak-angelicin after oral administration of Angelica dahurica extracts in mongrel dog plasma. The coumarin components and the internal standard isopsoralen were extracted from plasma samples with the mixture of tert-butyl methyl ether and n-hexane (4:1, v/v). Chromatographic separation was performed on a C(18) column (200 mm x 4.6mm, 5 microm) with the mobile phase acetonitrile-methanol-water-acetic acid (20:15:65:2, v/v/v/v) at a flow-rate of 1.0 ml/min. Only the peak of oxypeucedanin hydrate and byak-angelicin could be detected in dog plasma after oral administration of ethanol extracts of A. dahurica mainly containing xanthotoxol, osthenol, imperatorin, oxypeucedanin hydrate and byak-angelicin. The calibration curves of oxypeucedanin hydrate and byak-angelicin were linear over a range of 22.08-8830.00 and 6.08-2430.00 ng/ml in dog plasma, respectively. The quantification limit of oxypeucedanin hydrate and byak-angelicin in dog plasma was 22.08 and 6.08 ng/ml, respectively. The intra- and inter-day precision was less than 7.6% and 8.5% and the accuracy was from 91.9% to 106.1%. The lowest absolute recoveries of oxypeucedanin hydrate and byak-angelicin were 85.7% and 87.0%, respectively. The method was successfully applied to the pharmacokinetic studies of oxypeucedanin hydrate and byak-angelicin in dog plasma after oral administration of ethanol extracts from A. dahurica.

  14. Herb-drug interactions.

    Science.gov (United States)

    Fugh-Berman, A

    2000-01-08

    Concurrent use of herbs may mimic, magnify, or oppose the effect of drugs. Plausible cases of herb-drug interactions include: bleeding when warfarin is combined with ginkgo (Ginkgo biloba), garlic (Allium sativum), dong quai (Angelica sinensis), or danshen (Salvia miltiorrhiza); mild serotonin syndrome in patients who mix St John's wort (Hypericum perforatum) with serotonin-reuptake inhibitors; decreased bioavailability of digoxin, theophylline, cyclosporin, and phenprocoumon when these drugs are combined with St John's wort; induction of mania in depressed patients who mix antidepressants and Panax ginseng; exacerbation of extrapyramidal effects with neuroleptic drugs and betel nut (Areca catechu); increased risk of hypertension when tricyclic antidepressants are combined with yohimbine (Pausinystalia yohimbe); potentiation of oral and topical corticosteroids by liquorice (Glycyrrhiza glabra); decreased blood concentrations of prednisolone when taken with the Chinese herbal product xaio chai hu tang (sho-salko-to); and decreased concentrations of phenytoin when combined with the Ayurvedic syrup shankhapushpi. Anthranoid-containing plants (including senna [Cassia senna] and cascara [Rhamnus purshiana]) and soluble fibres (including guar gum and psyllium) can decrease the absorption of drugs. Many reports of herb-drug interactions are sketchy and lack laboratory analysis of suspect preparations. Health-care practitioners should caution patients against mixing herbs and pharmaceutical drugs.

  15. Ding Dong School (Skits and Things): Teaching Performance Art.

    Science.gov (United States)

    Clark, Laurie Beth

    2003-01-01

    Considers the relevance of a semester length curriculum in Performance for Art and Theatre students. Contends that art majors in performance classes learn to value more ephemeral content, to work with time, and to think explicitly about audience, while theatre majors have an opportunity to engage with original, personally expressive content and to…

  16. Botanicals and Their Bioactive Phytochemicals for Women’s Health

    Science.gov (United States)

    Dietz, Birgit M.; Hajirahimkhan, Atieh; Dunlap, Tareisha L.

    2016-01-01

    Botanical dietary supplements are increasingly popular for women’s health, particularly for older women. The specific botanicals women take vary as a function of age. Younger women will use botanicals for urinary tract infections, especially Vaccinium macrocarpon (cranberry), where there is evidence for efficacy. Botanical dietary supplements for premenstrual syndrome (PMS) are less commonly used, and rigorous clinical trials have not been done. Some examples include Vitex agnus-castus (chasteberry), Angelica sinensis (dong quai), Viburnum opulus/prunifolium (cramp bark and black haw), and Zingiber officinale (ginger). Pregnant women have also used ginger for relief from nausea. Natural galactagogues for lactating women include Trigonella foenum-graecum (fenugreek) and Silybum marianum (milk thistle); however, rigorous safety and efficacy studies are lacking. Older women suffering menopausal symptoms are increasingly likely to use botanicals, especially since the Women’s Health Initiative showed an increased risk for breast cancer associated with traditional hormone therapy. Serotonergic mechanisms similar to antidepressants have been proposed for Actaea/Cimicifuga racemosa (black cohosh) and Valeriana officinalis (valerian). Plant extracts with estrogenic activities for menopausal symptom relief include Glycine max (soy), Trifolium pratense (red clover), Pueraria lobata (kudzu), Humulus lupulus (hops), Glycyrrhiza species (licorice), Rheum rhaponticum (rhubarb), Vitex agnus-castus (chasteberry), Linum usitatissimum (flaxseed), Epimedium species (herba Epimedii, horny goat weed), and Medicago sativa (alfalfa). Some of the estrogenic botanicals have also been shown to have protective effects against osteoporosis. Several of these botanicals could have additional breast cancer preventive effects linked to hormonal, chemical, inflammatory, and/or epigenetic pathways. Finally, although botanicals are perceived as natural safe remedies, it is important for women and

  17. Botanicals and Their Bioactive Phytochemicals for Women's Health.

    Science.gov (United States)

    Dietz, Birgit M; Hajirahimkhan, Atieh; Dunlap, Tareisha L; Bolton, Judy L

    2016-10-01

    Botanical dietary supplements are increasingly popular for women's health, particularly for older women. The specific botanicals women take vary as a function of age. Younger women will use botanicals for urinary tract infections, especially Vaccinium macrocarpon (cranberry), where there is evidence for efficacy. Botanical dietary supplements for premenstrual syndrome (PMS) are less commonly used, and rigorous clinical trials have not been done. Some examples include Vitex agnus-castus (chasteberry), Angelica sinensis (dong quai), Viburnum opulus/prunifolium (cramp bark and black haw), and Zingiber officinale (ginger). Pregnant women have also used ginger for relief from nausea. Natural galactagogues for lactating women include Trigonella foenum-graecum (fenugreek) and Silybum marianum (milk thistle); however, rigorous safety and efficacy studies are lacking. Older women suffering menopausal symptoms are increasingly likely to use botanicals, especially since the Women's Health Initiative showed an increased risk for breast cancer associated with traditional hormone therapy. Serotonergic mechanisms similar to antidepressants have been proposed for Actaea/Cimicifuga racemosa (black cohosh) and Valeriana officinalis (valerian). Plant extracts with estrogenic activities for menopausal symptom relief include Glycine max (soy), Trifolium pratense (red clover), Pueraria lobata (kudzu), Humulus lupulus (hops), Glycyrrhiza species (licorice), Rheum rhaponticum (rhubarb), Vitex agnus-castus (chasteberry), Linum usitatissimum (flaxseed), Epimedium species (herba Epimedii, horny goat weed), and Medicago sativa (alfalfa). Some of the estrogenic botanicals have also been shown to have protective effects against osteoporosis. Several of these botanicals could have additional breast cancer preventive effects linked to hormonal, chemical, inflammatory, and/or epigenetic pathways. Finally, although botanicals are perceived as natural safe remedies, it is important for women and

  18. A molecular docking study of phytochemical estrogen mimics from dietary herbal supplements.

    Science.gov (United States)

    Powers, Chelsea N; Setzer, William N

    2015-01-01

    The purpose of this study is to use a molecular docking approach to identify potential estrogen mimics or anti-estrogens in phytochemicals found in popular dietary herbal supplements. In this study, 568 phytochemicals found in 17 of the most popular herbal supplements sold in the United States were built and docked with two isoforms of the estrogen receptor, ERα and ERβ (a total of 27 different protein crystal structures). The docking results revealed six strongly docking compounds in Echinacea, three from milk thistle (Silybum marianum), three from Gingko biloba, one from Sambucus nigra, none from maca (Lepidium meyenii), five from chaste tree (Vitex agnus-castus), two from fenugreek (Trigonella foenum-graecum), and two from Rhodiola rosea. Notably, of the most popular herbal supplements for women, there were numerous compounds that docked strongly with the estrogen receptor: Licorice (Glycyrrhiza glabra) had a total of 26 compounds strongly docking to the estrogen receptor, 15 with wild yam (Dioscorea villosa), 11 from black cohosh (Actaea racemosa), eight from muira puama (Ptychopetalum olacoides or P. uncinatum), eight from red clover (Trifolium pratense), three from damiana (Turnera aphrodisiaca or T. diffusa), and three from dong quai (Angelica sinensis). Of possible concern were the compounds from men's herbal supplements that exhibited strong docking to the estrogen receptor: Gingko biloba had three compounds, gotu kola (Centella asiatica) had two, muira puama (Ptychopetalum olacoides or P. uncinatum) had eight, and Tribulus terrestris had six compounds. This molecular docking study has revealed that almost all popular herbal supplements contain phytochemical components that may bind to the human estrogen receptor and exhibit selective estrogen receptor modulation. As such, these herbal supplements may cause unwanted side effects related to estrogenic activity.

  19. Rastreamento do câncer de mama: quais as tendências atuais?

    Directory of Open Access Journals (Sweden)

    Andréa Pires Souto Damin

    2012-07-01

    Full Text Available O câncer de mama é a neoplasia maligna mais frequente no mundo. No Brasil, representa a principal causa de morte por câncer em mulheres (1,2. Segundo o INCA (Instituto Nacional do Câncer são esperados 52 casos para 100.000 mulheres em 2012. Porto Alegre tem a maior incidência no país, com estimativa de 125 casos por 100.000 mulheres (2. Nesta edição da Revista do HCPA, um grupo de Minas Gerais avalia o papel da mamografia no rastreamento do câncer de mama. Até o momento, não existe prevenção primária efetiva para o câncer de mama. Como apresenta uma fase subclínica longa, variando entre 2 e 4 anos, a diminuição da mortalidade depende da detecção precoce. A sobrevida da doença em estágios iniciais pode alcançar 98% em 5 anos (1.

  20. Quais Fatores Influenciam a Taxa de Aprovação na Disciplina de Anatomia Humana?

    Directory of Open Access Journals (Sweden)

    Julia Silva-e-Oliveira

    Full Text Available RESUMO A Anatomia Humana (AH é uma disciplina básica para todos os estudantes dos cursos superiores das áreas da saúde e biológica. A maior parte a considera de conteúdo difícil. O ensino da AH precisa ser repensado no contexto da política atual de acesso amplo ao ensino superior. E corresponder ao dever das instituições de proporcionar ao estudante uma formação de qualidade com vistas à formação de um profissional crítico e de perfil criativo frente às distintas situações do cotidiano. É preciso entender possíveis fatores que levam às elevadas taxas de reprovação nesta disciplina. Portanto, o objetivo do presente estudo foi relacionar o resultado do vestibular/Enem com hábitos de estudo e desejo profissional no desempenho acadêmico da disciplina dos alunos dos cursos de Educação Física, Ciências Biológicas e Nutrição do IF Sudeste MG. Foram entrevistados 129 alunos. A pontuação do vestibular/Enem foi maior entre os aprovados em AH; não houve entre os grupos diferença quantitativa nas horas de estudo e tampouco na escolha do curso, que ocorreu por opção do aluno (versus por falta de opção.

  1. Significados do trabalho e do dinheiro: Quais suas funções sociais?

    Directory of Open Access Journals (Sweden)

    Sabrina Cavalcanti Barros

    2018-03-01

    Full Text Available Estudos sobre o trabalho e o dinheiro têm enfatizado a dimensão institucional desses fenômenos, destacando funções como a capacidade de interligar a satisfação das necessidades individuais e a manutenção da ordem social. Tais funções são ativadas no cotidiano dos indivíduos, sendo construídas socialmente na produção dos significados dos referidos fenômenos. Exploramos as funções que os significados do trabalho e do dinheiro cumpriram na vida dos operários da construção civil. Realizamos entrevistas semiestruturadas com 44 operários e desenvolvemos análise de conteúdo temática. Identificamos dois grandes eixos norteadores: inclusão e inserção sociais versus exclusão social e realização e sentido de utilidade versus degradação. Os resultados indicaram que as condições de trabalho precárias e a escassez de dinheiro estruturaram os modos de enfrentamento dessas realidades, na valorização dos benefícios alcançados, na naturalização e no conformismo, decorrentes da dureza e limitação de oportunidades experimentadas por esses trabalhadores. Limitações da pesquisa e sugestões são apontadas.

  2. Quais os parâmetros funcionais que permitem diferenciar asma grave de DPOC?

    Directory of Open Access Journals (Sweden)

    Ricardo Marques Dias

    2010-03-01

    Full Text Available Resumo: Com o objectivo de identificar parâmetros funcionais respiratórios que contribuam para o diagnóstico diferencial entre asma e DPOC, estudámos 20 asmáticos e 30 bronquíticos, com ou sem enfisema, com os exames usuais de função pulmonar: espirografia, pletismografia e DLCO, pré e pós-broncodilatação para os dois primeiros exames. Os grupos apresentam diferenças significativas na sua constituição. Os asmáticos são mais jovens, média de 48 anos, contra 59 anos no grupo com DPOC, e o grupo é constituído predominantemente por mulheres, 65% contra 40%, respectivamente. Os exames funcionais pulmonares, realizados conforme as directrizes internacionais, mostram, pela espirografia, que os asmáticos têm obstrução mais intensa, VEF1/CVF de 59 versus 66 e maior resposta broncodilatadora pelo VEF1, quer em valor absoluto, quer por variação percentual, do basal (% ou do valor previsto (%P. A DLCO mostra-se, em média, normal entre os asmáticos, 103%P, e diminuída no grupo com DPOC, 69%P. Na pletismografia constatámos que os asmáticos têm maior volume residual (%P e resistência de vias aéreas. Concluímos que vários parâmetros funcionais diferenciam a asma da DPOC, como um grupo; na análise individual, a DLCO é o parâmetro que melhor discrimina as duas doenças, possuindo maior especificidade para o diagnóstico de DPOC, seguida pelas variações de VEF1 na broncodilatação, com maior sensibilidade para o diagnóstico de asma. Desta forma, estes dois exames são destaque no diagnóstico diferencial das doenças obstrutivas.Rev Port Pneumol 2010; XVI (2: 253-272 Abstract: The aim of this study was to identify the respiratory function parameters that help in the accurate diagnosis of asthma and COPD. We studied 20 asthma and 30 COPD patients who underwent lung function tests including spirometry and plethysmography both with bronchodilator test and diffusion with carbon monoxide (DLCO. The tests were performed according to International Guidelines (ATS/ERS. The asthma patients were younger (mean age=48 than those in the COPD group (mean age=59 and this group also had more female patients (65% than the COPD group (40%. The results showed a more severe obstruction in the asthma group: FEV1/FVC=59% versus 66% for COPD. There was also a greater bronchodilator response as shown by changes in absolute and percentage values for FEV1 in the asthma group. Average DLCO values were normal in the asthma group (103%P and lower in the COPD (69%. In plethysmography the asthma group had a higher residual volume (%P and a higher airway resistance. We concluded that many functional parameters were useful in distinguishing the asthma and COPD groups. In individual analysis, DLCO was the parameter which best aided in an accurate diagnosis in both groups, with a higher specificity for COPD. The bronchodilator response measured by changes in FEV1 showed a higher sensitivity for asthma. Thus, these two tests are highlighted in the differential diagnosis of obstructive diseases.Rev Port Pneumol 2010; XVI (2: 253-272 Palavras-chave: Testes de função pulmonar, asma, DPOC, Key-words: Lung function test, asthma, COPD

  3. Narrated Landscape as Counterweight to Perception of Placelessness in Contemporary Urban Landscape: Re-Visioning Place in Gwangbok-Dong and Nampo-Dong, Busan, South Korea

    Science.gov (United States)

    Lee, Sungkyung

    2009-01-01

    Although the contemporary commercial urban landscape is often assessed as placeless, this research proposes that even these seemingly anonymous places are repositories of thriving community values and meanings. Seeking a more complex reading, this research extends the scope of analysis from physical space to human use in order to reveal the…

  4. Which factors could explain the low birth weight paradox? Quais fatores podem explicar o paradoxo do baixo peso ao nascer?

    Directory of Open Access Journals (Sweden)

    Antônio Augusto Moura da Silva

    2006-08-01

    Full Text Available OBJECTIVE: Low birth weight children are unusual among well-off families. However, in Brazil, low birth weight rate was higher in a more developed city than in a less developed one. The study objective was to find out the reasons to explain this paradox. METHODS: A study was carried out in two municipalities, Ribeirão Preto (Southeastern Brazil and São Luís (Northeastern Brazil, which low birth weight rates were 10.7% and 7.6% respectively. Data from two birth cohorts were analyzed: 2,839 newborns in Ribeirão Preto in 1994 and 2,439 births in São Luís in 1997-1998. Multiple logistic regression analysis was performed, adjusted for confounders. RESULTS: Low birth weight risk factors in São Luís were primiparity, maternal smoking and maternal age less than 18 years. In Ribeirão Preto, the associated variables were family income between one and three minimum wages, maternal age less than 18 and equal to or more than 35 years, maternal smoking and cesarean section. In a combined model including both cohorts, Ribeirão Preto presented a 45% higher risk of low birth weight than São Luís. When adjusted for maternal smoking habit, the excess risk for low birth weight in Ribeirão Preto compared to São Luís was reduced by 49%, but the confidence interval was marginally significant. Differences in cesarean section rates between both cities contributed to partially explain the paradox. CONCLUSIONS: Maternal smoking was the most important risk factor for explaining the difference in low birth weight between both cities. The other factors contributed little to explain the difference in low birth weight rates.OBJETIVO: O baixo peso ao nascer é incomum em recém-nascidos de maior nível socioeconômico. Contudo, no Brasil, a taxa de baixo peso ao nascer foi maior em cidade mais desenvolvida do que em município menos desenvolvido. O objetivo do estudo foi buscar razões para explicar este paradoxo. MÉTODOS: O estudo foi realizado em Ribeirão Preto (SP e em São Luís (MA, cujas taxas de baixo peso ao nascer eram 10,7% e 7,6%, respectivamente. Foram analisados dados de duas coortes de nascimentos: 2.839 recém-nascidos em Ribeirão Preto em 1994 e 2.439 em São Luís em 1997/98. Foi realizada análise de regressão logística múltipla, ajustada para efeito de confusão. RESULTADOS: Os fatores de risco associados em São Luís foram primiparidade, idade materna menor que 18 anos e tabagismo materno. Em Ribeirão Preto, os fatores de risco foram: renda familiar entre um e três salários-mínimos, idade materna menor que 18 e igual ou maior que 35 anos, tabagismo materno e parto cesáreo. Em modelo conjunto incluindo ambas as coortes, Ribeirão Preto apresentou risco 45% maior para em relação a São Luís. Quando ajustado para tabagismo materno, o excesso de risco em Ribeirão Preto, reduziu-se em 49%, mas o intervalo de confiança esteve marginalmente significante. Diferenças nas taxas de cesárea entre as duas cidades contribuíram para explicar uma porção adicional desse paradoxo. CONCLUSÕES: O tabagismo materno foi o fator de risco mais importante capaz de explicar a diferença no baixo peso ao nascer entre as duas cidades. Os outros fatores pouco contribuíram para explicar a diferença nas taxas de baixo peso ao nascer.

  5. Quais as relações da Educação Física com os Movimentos Sociais?

    Directory of Open Access Journals (Sweden)

    Paulo Ricardo do Canto Capela

    2000-01-01

    Full Text Available RESUMO: Começo minha exposição problematizando o próprio tema que me foi sugerido para dissertar. A pergunta/tema indica para uma curiosidade sobre as possíveis relações entre Educação Física e Movimentos Sociais.

  6. History of Biochemistry at the University of Geneva From the Boulevard des Philosophes to Quai Ernest-Ansermet.

    Science.gov (United States)

    Deshusses, Jacques; Riezman, Howard

    2009-12-01

    A brief account of the developments in biochemistry at the Faculty of Science of the University of Geneva is given from its emergence from organic chemistry at the Ancienne Ecole de chimie to today's Department of Biochemistry at the Section de chimie et biochimie.

  7. Escolhas familiares, estratificação educacional e desempenho escolar: quais as relações

    Directory of Open Access Journals (Sweden)

    Fátima Alves

    2010-01-01

    Full Text Available Dans cet article, on recherche les effets des choix familiaux d'établissements d'enseignement sur l'apprentissage d'élèves d'origines sociales diverses fréquentant les premières années de l'enseignement primaire dans la ville de Rio de Janeiro. On part de données d'un projet longitudinal sur des enfants qui débutent en deuxième année de cet enseignement en 2005. Selon leurs résultats, les variables concernant les différents choix familiaux indiquent des effets significatifs sur l'apprentissage des élèves en lecture, indépendamment de leurs conditions économiques ou de leur apprentissage préalable. L'effet du choix familial de rechercher une école de qualité malgré sa distance du domicile de l'élève, est assez important.

  8. How do we sell the hygiene message? With dollars, dong or excreta?

    DEFF Research Database (Denmark)

    Jensen, Peter Kjaer Mackie; Phuc, Pham Duc; West, Line Gram Knudsen

    2010-01-01

    . However, farmers in this region cannot afford to follow these guidelines and this paper presents the reasons why.In their efforts to ensure optimal hygienic conditions, by providing a guideline, the Vietnamese health authorities have not put sufficient attention to the 'excreta economy' in relation...... the hygiene message for most Vietnamese farmers. Even at national level the excreta economy has an impact. If Vietnam were to replace human excreta with imported fertilizer, it would involve an extra national expenditure of at least US$ 83 million a year.In order to convince Vietnamese farmers to adopt...... different fertilizing methods when reusing human excreta, it is necessary for the Vietnamese health authorities to change their hygiene message. They need to replace their current health sector-specific approach with a holistic one that takes the premises of farmers' livelihoods into account. If they do...

  9. Liukeng:SECRET OF LOYALTY OF THE DONG FAMILY BLOOD AND ETHICS

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    Why is it that the Liukeng village has been preserved so well after five or six dynasties?Why is it that a small village produced so many successful imperial examination candidates,provincial level successful examination candidates,officials and business people?Why is it that this family clan can unite as one without decline for thousand years?

  10. Comparison and Research on New Rural Community Management Patterns of Shan Dong Province

    Science.gov (United States)

    Fang, Lei; Zhang, Xiaomei

    Rural community is an important institutional innovation,which has important effect and edification to future new rural management.There are three new rural community management patterns in shandong province:divisions of the village community,many villages community and village merge community. This article not only introduce three models,but also compare them in four aspects: community scale, community management,infrastructure,resource utilization.Pointing out the strength and weakness of three models.Drawing a conclusion that village merge community is the active reaction for rural urbanization. And could be the important recommended breed.

  11. Antitumor and Antibacterial Derivatives of Oridonin: A Main Composition of Dong-Ling-Cao

    Directory of Open Access Journals (Sweden)

    Dahong Li

    2016-04-01

    Full Text Available Isodon rubescens has been used as a traditional green tea for more than 1000 years and many medicinal functions of I. rubescens are also very useful, such as its well-known antitumor and antibacterial activities. Oridonin, a bioactive ent-kaurane diterpenoid, is the major ingredient of this medicinal tea. Herein, 22 novel oridonin derivatives were designed and synthesized. The antibacterial activity was evaluated for the first time. Compound 12 was the most promising one with MIC of 2.0 μg/mL against B. subtilis, which was nearly 3-fold stronger than positive control chloromycetin. The antiproliferative property was also assayed and compound 19 showed stronger activity than taxol. The apoptosis-inducing ability, cell cycle arrest effect at S phase and influence of mitochondrial membrane potential by 19 in CaEs-17 cancer cells were first disclosed. Based on the above results, the cell apoptosis induced by compound 19 in CaEs-17 cells was most probably involved in the intrinsic apoptotic pathway.

  12. Overall view of the AA hall dominated by the 50 ton crane (Donges).

    CERN Multimedia

    1980-01-01

    A 50 ton, 32 metre span overhead travelling cranre was mounted in one of the bays of Hall 193 (AA). An identical crane was mounted on the other bay. See also photo 8004261. For photos of the AA in different phases of completion (between 1979 and 1982) see: 7911303, 7911597X, 8004261, 8004608X, 8005563X, 8005565X, 8006716X, 8006722X, 8010939X, 8010941X, 8202324, 8202658X, 8203628X .

  13. Ding Dong, You've Got Mail! A Lab Activity for Teaching the Internet of Things

    Science.gov (United States)

    Frydenberg, Mark

    2017-01-01

    Connecting ordinary devices to the Internet is a defining characteristic of the Internet of Things. In this hands-on lab activity, students will connect a wireless doorbell to the Internet using a Raspberry Pi computer. By modifying and running a program on the Raspberry Pi to send an email or text message notifying a recipient that someone is at…

  14. Engenharia e construção: quais variáveis contribuem para o sucesso dos projetos executados atualmente no Brasil?

    OpenAIRE

    Berssaneti,Fernando Tobal; Assumpção,André; Nakao,Osvaldo Shigeru

    2014-01-01

    Em tempos de grandes obras (eventos esportivos 2014 e 2016, plano de aceleração do crescimento do governo federal e setor petroquímico), este artigo busca identificar variáveis que contribuem para o sucesso dos projetos de engenharia e construção executados atualmente no Brasil. O relacionamento entre a presença de certas variáveis independentes e o sucesso dos projetos foi testado em termos de um conjunto de indicadores de desempenho em projetos, que envolve: conformidade com orçamento (cust...

  15. Engenharia e construção: quais variáveis contribuem para o sucesso dos projetos executados atualmente no Brasil?

    Directory of Open Access Journals (Sweden)

    Fernando Tobal Berssaneti

    Full Text Available Em tempos de grandes obras (eventos esportivos 2014 e 2016, plano de aceleração do crescimento do governo federal e setor petroquímico, este artigo busca identificar variáveis que contribuem para o sucesso dos projetos de engenharia e construção executados atualmente no Brasil. O relacionamento entre a presença de certas variáveis independentes e o sucesso dos projetos foi testado em termos de um conjunto de indicadores de desempenho em projetos, que envolve: conformidade com orçamento (custo; cronograma (tempo; especificações técnicas (requisitos do produto/serviço; e atendimento às demandas dos clientes. Foi analisado o efeito de três variáveis de entrada: apoio da alta administração, existência de um gerente de projetos dedicado e a presença de uma estrutura formal de gerenciamento de projetos (Escritório de Gerenciamento de Projetos. Para testar as hipóteses da pesquisa, foi desenvolvido um estudo empírico, adotando-se uma abordagem quantitativa, com um levantamento ("survey" junto a 120 profissionais relacionados ao setor de engenharia e construção. Considerando-se o triângulo de ferro (prazo, custo e qualidade, identificou-se que há relação entre a presença de um gerente de projeto dedicado e o cumprimento do orçamento planejado e há relação entre a presença de um gerente de projeto dedicado e o cumprimento dos prazos dos projetos executados. Contudo, a visão ampliada de qualidade, envolvendo também a satisfação do cliente, não foi confirmada.

  16. QUAIS SABERES SÃO MOBILIZADOS PARA SUPRIR AS LACUNAS NA FORMAÇÃO INICIAL REFERENTES À HISTÓRIA DA CIÊNCIA?

    Directory of Open Access Journals (Sweden)

    Fernando Bastos

    2011-12-01

    Full Text Available Nowadays it is increasingly required insertion History of Science on content to be worked in education, which raises many doubts and difficulties on the teachers did not have that content in their initial training. This work results from a qualitative empirical study aimed to investigate how a teacher of Biology and Science in a public school in the city of Bauru - SP was not in their initial training courses relating to the History of Science, mobilizes their knowledge to enter such an approach in their teaching practice. In the research methodology used as its theme the history of DNA present in the materials and also conduct open interviews and field notes to identify the knowledge involved in teaching practice and was adopted as the theoretical framework of Maurice Tardif’s Docent Knowledge. The results showed that even with difficulties arising from gaps in initial training, the teacher resorted to their experiential knowledge to meet these needs in addition to appropriate knowledge from the programs and textbooks, but its shortcomings make it difficult to analyze more critically. Thus, these data lead us to a reflection on the role of textbooks for these teachers is the process by which the consolidation of the knowledge they constructed.

  17. Quem é o bibliotecário? Qual sua formaçao? E, quais sao suas distintas funçoes no mercado de trabalho?

    Directory of Open Access Journals (Sweden)

    Lic. Patrícia Martins Pereira

    1998-01-01

    Full Text Available Ao apresentarmos nossa escolha pela graduação em Biblioteconomia, num país e em uma capital, onde bibliotecas, profissionais da informação (bibliotecários, acervos e qualidade da informação, encontram-se em estado de "Indigente social", termo sempre utilizado por mim. Chegamos a ser desconsiderados por nossa escolha acadêmica/ Profissional, onde é colocado que: desviamos de um curso bastante concorrido, ou que somos ressentidos por falta de cultura.

  18. Impact of Participatory Irrigation Management (PIM) to Local Communities and Environment in Hop Tien Commune, Dong Hy

    NARCIS (Netherlands)

    Wageningen International,

    2008-01-01

    This case-study is designed to support the development of the Viet Nam – Netherlands Water Partnership on Water for Food and Ecosystems. The partnership is between Viet Nam’s Ministry of Agriculture and Rural Development (MARD) and the Netherlands Ministry of Agriculture, Nature and Food Quality

  19. Korean Confucianism's Mindful Learning Model of Moral Internalization as Manifested in the Cheonghak-Dong Hermit Community

    Science.gov (United States)

    Yoo, Si Ha

    2012-01-01

    The purpose of this qualitative study is to understand an unknown educational approach in Korean Confucianism's ethical education characterized as moral internalization, based on the study participants. A prevailed understanding of moral internalization of Confucianism is a strong imposed learning process, which is a well known Asian learning…

  20. Observation électorale et réseaux d'ONG transnationaux : le cas du Kirghizstan

    OpenAIRE

    Boris Petric

    2008-01-01

    The Tulip Revolution in Kyrgyzstan highlights the globalization of this political space where a complex architecture of actors fights to control the power. The democratic assistance has facilitated the birth of new kind of local actors like Koalitsia, a national NGO’s network. This NGO coalition played a key role as electoral observers. Beyond actors, Koalitsia expresses the emergence of a new transnational political system which muschroomed in different parts of the world and which modifies ...

  1. Comparison of elevation derived from insar data with dem from topography map in Son Dong, Bac Giang, Viet Nam

    Science.gov (United States)

    Nguyen, Duy

    2012-07-01

    Digital Elevation Models (DEMs) are used in many applications in the context of earth sciences such as in topographic mapping, environmental modeling, rainfall-runoff studies, landslide hazard zonation, seismic source modeling, etc. During the last years multitude of scientific applications of Synthetic Aperture Radar Interferometry (InSAR) techniques have evolved. It has been shown that InSAR is an established technique of generating high quality DEMs from space borne and airborne data, and that it has advantages over other methods for the generation of large area DEM. However, the processing of InSAR data is still a challenging task. This paper describes InSAR operational steps and processing chain for DEM generation from Single Look Complex (SLC) SAR data and compare a satellite SAR estimate of surface elevation with a digital elevation model (DEM) from Topography map. The operational steps are performed in three major stages: Data Search, Data Processing, and product Validation. The Data processing stage is further divided into five steps of Data Pre-Processing, Co-registration, Interferogram generation, Phase unwrapping, and Geocoding. The Data processing steps have been tested with ERS 1/2 data using Delft Object-oriented Interferometric (DORIS) InSAR processing software. Results of the outcome of the application of the described processing steps to real data set are presented.

  2. Power start up of the Dalat nuclear research reactor; Khoi dong nang luong lo phan ung hat nhan Da Lat

    Energy Technology Data Exchange (ETDEWEB)

    Hien, Pham Duy; Huy, Ngo Quang; Long, Vu Hai; Mai, Tran Khanh [Nuclear Research Inst., Da Lat (Viet Nam)

    1994-10-01

    After accomplishing the physical start-up of the reactor, the power start-up was carried out in February 1984. The power of the reactor has reached: 10 KW on 6/2/1984, 100 KW on 7/2/1984, 200 KW and 300 KW on 8/2/1984; 400 KW and nominal power 500 KW on 9/2/1984. The reactivity temperature coefficient and the xenon poisoning were determined. 3 figs., 12 tabs.

  3. Bio-pesticidal and Antimicrobial Coumarins from Angelica dahurica (Fisch. Ex Hoffm

    Directory of Open Access Journals (Sweden)

    Qian Xie

    2016-05-01

    Full Text Available The air-dried aerial parts of Croton campestris, C. chaetocalyx, C. eriocladus, and C. glandulosus, with occurrence in the Eastern Brazilian Amazon, yielded essential oils, and their volatile constituents were analyzed by GC and GC-MS. Sesquiterpenes, both hydrocarbons and oxygenated, were the most highly represented classes in the oils: the former ranging from 55.3% to 85.1%, and the latter varying from 7.2% to 33.2%. The oils were separated into two groups using hierarchical cluster analysis whose main constituents were β-caryophyllene, germacrene D, γ-elemene, β-elemene, α-humulene and δ-elemene (Group A, C. campestris and C. eriocladus; and spathulenol, bicyclogermacrene, δ-elemene, germacrene D, β-caryophyllene and δ-cadinene (Group B, C. chaetocalyx and C. glandulosus. Percentage of sesquiterpene hydrocarbons was higher in Group A (83-85% than in Group B (55-63%. However, regarding the oxygenated sesquiterpenes, it was reversed, being bigger in Group B (28-33% than in Group A (7-8%. Percentage of similarity in Group A was 92% and in Group B it was 86%. These chemotaxonomic results showed a significant contribution for the better botanical knowledge of these four Croton species occurring in North Brazil.

  4. Technology development for recovery of individual rare earth elements at high purity from Dong-Pao rare earth concentrated ore of Vietnam

    International Nuclear Information System (INIS)

    Hoang Nhuan; Le Ba Thuan; Luu Xuan Dinh; Tran Hoang Mai; Tran Thi Hong Thai; Yoshiuyki Aiba; Hiroaki Nishimura

    2015-01-01

    In this work, the research results on RE processing process at laboratory scale and pilot scale was reported and discussed. Experimental research on thermal decomposition and sulfate process of bastnaesite ore with sulfuric acid in electric furnace was carried out, the different roasting conditions, mass transfer rate, reactions and RE and/or non-RE behaviors during roasting and leaching were investigated. The roasting temperatures were 450"oC and 550"oC. With higher roasting temperature and longer roasting time, the RE recovery yield reduced. The RE recovery yield reached the highest (over 94%) at roasting temperature of 550"oC for 2 hrs. The different extracting conditions for separation of REEs were investigated in laboratory scale as well as pilot scale. At pilot scale, the separation of REEs was performed on 120-stage extraction system produced by Japan, using PC88A solvent dissolved in IP2028. The volume of each stage was 20 L. The results showed that REEs were separated from RE resource of Vietnam and individual RE elements such as La, Ce, Pr, and Nd were obtained at high purity. The parameters for each extraction stage were reported in this work. The results indicated that in order to obtain highly purified Nd (>99%), it needs to use an extraction system with higher stage number, about 200 stages. The extraction data at pilot scale of this investigation was used as basic data for calculating parameters for extraction system in industrial scale. (author)

  5. [Characteristics of non-marital and non-commercial heterosexual transmission of HIV infection in Miao-Dong Autonomous prefecture of Qiandongnan].

    Science.gov (United States)

    Yu, Q Y; Wang, F L; Xu, P; Wen, H J; Xiong, Y X; Yang, J; Long, Y; He, H J; Shi, J; Lyu, P

    2017-11-06

    Objective: The goal of this research was to understand the demographic distribution and related factors of non-marital and non-commercial heterosexual transmission (non-commercial transmission) for HIV/AIDS (human immunodeficiency virus/acquired immunodeficiency syndrome). Methods: Data related to HIV/AIDS infected by non-marital heterosexual transmission and whose present address was in Qian Dongnan, were collected from Information System on the HIV/AIDS Prevention and Control. Information included demographic characteristics, the members of non-marital sex partners, transmission path, detection source, CD4(+)T lymphocyte level, et al. cases belong to homosexual history, injective drug use or non-classified non-marital heterosexuality transmission were excluded, totally collect HIV/AIDS 919 cases. Multivariate logistic regressions were used to analyze potential factors associated with non-marital and non-commercial heterosexual transmission. In addition, in March and June 2017, using a convenience sampling, we conducted one-to-one interviews among 10 HIV/AIDS who were infected by non-marital heterosexuality and had non-marital and non-commercial heterosexual experience in Kaili Center for Disease Control and Prevention. The content of the interview included basic information, sexual orientation, the main place of making friends and sexual behavior, attitude to commercial heterosexuality and non-martial and non-commercial heterosexuality and so on. Results: Out of the 919 cases, 645 (70.2%) were male, the proportion of non-commercial transmission was 55.06% (506). The proportion of female HIV/AIDS with non-commercial transmission was 84.7% (232), which was higher than male (42.5%(274)) (χ(2)=138.35, Pcommercial transmission was 61.5% (275), which was higher than other religion (52.2%(412)) (χ(2)=6.32, P= 0.012). The proportion of HIV/AIDS with non-commercial transmission who had 0-5 non-marital sexual partners was 58.8% (498), which was higher than who had>5 non-marital sexual partners (11.1%(8)) (χ(2)=61.10, Pcommercial transmission who lived mobile was 72.9% (94), which was higher than who lived fixedly (52.2%(412)) (χ(2)=19.34, Pcommercial heterosexual transmission in Qian dongnan was higher than general national levels. The characteristics of sex, marriage status, migration, vocation, the members of non-marital sex partners were significant differed between commercial heterosexual transmission and non-marital and non-commercial heterosexual transmission.

  6. Study On Beneficiation Technology Of Dong Pao Rare-Earth-Barite-Fluorite With Two Product Plans About Content And Recovery Of Rare-Earth Fine Ores

    International Nuclear Information System (INIS)

    Duong Van Su; Truong Thi Ai; Bui Ba Duy; Bui Thi Bay; Nguyen Hong Ha; Le Thi Hong Ha; Doan Thi Mo; Doan Dac Ban; Nguyen Hoang Son

    2014-01-01

    The ore sample used in the research was taken from the F3 ore bodies and the sample of the F7, F9 and F16 ore bodies which contain the average of 5.98% TR 2 O 3 ; they are multi-metals ore which is difficult to enrich, highly weather with very complex ingredients. The process of the experiment is the ore is crushed, ground, screened and classified reasonably to -0.1 mm and divided into 3 particle size with the following technique: (1) -0.020 mm is primary sludge and the rare-earth fine ore; (2) 0.075-1 mm is gotten through the sludge concentrating table with the output is the 2 parts: the heavy part which is dried magnetic separator with high magnetism to get the rare-earth fine ore and the light one; (3) Light minerals, non-magnetic and ferromagnetic minerals group are ground together to 85% of them get size within -0.075 mm then mix it with 0.020-0.075 mm group. Using flotation separator, get barite-rare earth mixture and fluorite. After that, we separate this mixture by secondary flotation and get refined rare earth, barite and fluorite mineral. The result of the theme: (1) product plan A-rare-earth fine ore has TR 2 O 3 content archive 42.07% with recovery is 69.70%; (2) product plan B-rare-earth fine ore has TR 2 O 3 content archive 29.64% with recovery is 80.01%. (author)

  7. Gestão estratégica de recursos humanos: quais práticas influenciam a avaliação dessa função pelos membros organizacionais? [doi: 10.5329/RECADM.2014020

    Directory of Open Access Journals (Sweden)

    Camila Camargo

    2014-12-01

    Full Text Available Este artigo apresenta uma análise da influência das práticas de recursos humanos sobre a avaliação que os funcionários fazem da Competência da Gestão de Recursos Humanos nas suas organizações. Tal objetivo foi levado a termo com a realização de um levantamento com 347 funcionários de 8 organizações de serviços. Foram testadas nove hipóteses acerca da relação entre as práticas de RH e a avaliação da Competência da Gestão de RH dessas organizações. Por meio da aplicação de uma Análise de Regressão Múltipla verificou-se que a consideração de variáveis de recompensa (Remuneração e Benefícios não altera substancialmente o poder explicativo do modelo acerca da variação na atitude dos funcionários em relação à Competência da Gestão de RH, o que coloca maior peso sobre as variáveis denominadas Condições de Trabalho. Entre as Condições de Trabalho a variável Comunicação é a que apresenta maior influência sobre o julgamento da Competência da Gestão de RH. Tal achado coloca em primeiro plano o desenvolvimento das ações de Comunicação para reconhecimento do papel estratégico da Gestão de Recursos Humanos. Palavras-Chave Práticas de recursos humanos; gestão de recursos humanos; competência, status.     STRATEGIC HUMAN RESOURCE MANAGEMENT: WHICH PRACTICES INFLUENCE ASSESSMENT OF THIS FUNCTION BY ORGANIZATIONAL MEMBER?   ABSTRACT This paper provides an analysis of the influence of human resource practices on the evaluation that employees make related to Competence of Human Resource Management in their organizations. This purpose was brought to an end with the completion of a survey of 347 employees in eight service organizations in Brazil. We tested nine hypotheses about the relationship between HR practices and assessing the Competence of HR Management of these organizations. Through the application of a Multiple Regression Analysis it was found that the consideration of compensation variables (Compensation and Benefits does not markedly modify the model´s explanatory power about the change in the attitude of employees concerning the Competence of HR Management, which gives much importance on the variables called Working Conditions. Among Working Conditions the variable Communication is the one, which has more influence on the judgment of Competence of HR Management. This finding places at the forefront the development of social communication for recognizing the strategic role of Human Resource Management.   Keywords Human resource practices; human resource management; competence; status. 

  8. Quais as características propostas pelo BIRADS-US que melhor diferenciam nódulos malignos dos benignos? What characteristics proposed by BIRADS ultrasound better distinguish between benign and malignant nodes?

    Directory of Open Access Journals (Sweden)

    Eduardo Carvalho Pessoa

    2007-12-01

    Full Text Available OBJETIVO: analisar qual das características propostas pelo BIRADS-US tem maior impacto na diferenciação das lesões benignas das malignas. MÉTODOS: estudamos as características ultra-sonográficas do BIRADS em 384 nódulos submetidos à biópsia percutânea no período de fevereiro de 2003 a dezembro de 2006. Utilizou-se, para o exame, o aparelho Logic 5, com transdutor linear multifreqüencial de 7,5-12 MHz. A análise ultra-sonográfica do nódulo foi baseada no BIRADS-US levando em conta: forma, orientação, margem, limites da lesão, ecogenicidade, características acústicas posteriores, o tecido circunjacente e a presença de calcificações. Estes dados foram submetidos à análise estatística com modelo de regressão logística. Para o estudo de associação entre estas variáveis utilizamos o teste do c² e também calculamos a sensibilidade e a especificidade das variáveis "tecido ao redor", "calcificações", "efeito posterior", "limite da lesão" e "orientação". RESULTADOS: as lesões benignas representaram 42,4% e as malignas, 57,6%. A análise por regressão logística encontrou odds ratio (OR aumentado para câncer de 7,7 vezes quando o tecido ao redor esteve alterado, de 6,2 vezes quando houve presença das microcalcificações no interior das lesões, de 1,9 quando o efeito acústico foi sombra, de 25,0 vezes quando houve o halo ecogênico e de 7,1 vezes quando a orientação foi não paralela. CONCLUSÕES: dentre as características estudadas, o limite da lesão, representado pela presença ou não do halo ecogênico, é o mais importante diferenciador das massas benignas das malignas.PURPOSE: to analyze which characteristics proposed by the BIRADS lexicon for ultrasound have the greatest impact on distinguishing between benign and malignant lesions. METHODS: ultrasonography features from the third edition of the BIRADS were studied in 384 nodes submitted to percutaneous biopsy from February 2003 to December 2006, at the Medical School of Botucatu. For the ultrasonography, the equipment Logic 5 with a 7.5-12 MHz multifrequential linear transducer was used. The ultrasonography analysis of the node considered the features proposed by the BIRADS lexicon for ultrasound. The data were submitted to statistical analysis by the logistic regression model. RESULTS: the benign lesions represented 42.4% and the malignant, 57.6%. The logistic regression analysis found an odds ratio (OR for cancer of 7.69 times when the surrounding tissue was altered, of 6.25 times when there were microcalcifications in the lesions interior, of 1.95 when the acoustic effect is shadowing, of 25.0 times when there was the echogenic halo, and of 7.14 times when the orientation was non-parallel. CONCLUSIONS: among the features studied, the lesion limit, represented by the presence or not of the halogenic halo, is the most important differentiator of the benign from the malignant masses.

  9. Atividades experimentais e atividades baseadas em simulações computacionais: quais os principais fatores que influenciam a decisão de professores de conduzir ou não essas práticas em suas aulas?

    Directory of Open Access Journals (Sweden)

    Leonardo Albuquerque Heidemann

    2014-12-01

    Full Text Available Diversos são os trabalhos que têm apontado potencialidades relacionadas ao uso de Atividades Experimentais (AE e Atividades baseadas em Simulações Computacionais (ASC no ensino de Física. No entanto, a realidade das escolas tem mostrado que poucos são os professores que implementam tais recursos didáticos de forma sistemática em suas aulas. Neste trabalho, buscamos analisar os principais fatores que influenciam na decisão de professores de Física de usar ou não AE e ASC como estratégias de ensino. Amparados na Teoria do Comportamento Planejado de Icek Ajzen, nossos dados indicam que, além de aspectos relacionados com a infraestrutura disponível e com a capacidade que os professores acreditam possuir para a condução dessas atividades, fatores relacionados aos seus conhecimentos teóricos sobre as potencialidades e limitações das AE e ASC no ensino de Física também influenciam nas suas intenções de utilizarem-nas. Os resultados sugerem que os cursos de formação de professores devem direcionar seus esforços não somente no sentido de familiarizar os futuros docentes com um grande leque de experimentos e simulações que os capacitem para utilizarem AE e ASC como estratégias didáticas, mas também para torná-los cientes das potencialidades e limitações teóricas dessas estratégias.

  10. Quais são as nossas diferenças? Reflexões sobre a convivência com o diverso em escolas italianas What are our differences? Reflections about cohabitation with diversity in italian schools

    Directory of Open Access Journals (Sweden)

    Maria Beatriz Rodrigues

    2005-12-01

    Full Text Available O artigo considera a lei Basaglia, do fechamento dos manicômios, como um divisor de águas na sociedade italiana no tocante ao enfrentamento do tema diversidade. Examina, baseado em uma experiência de três anos em escolas italianas, a operacionalização de outra lei que segue os mesmos princípios e prevê a freqüência de todas as crianças, normo- e infra- dotadas, em escolas regulares e que aboliu as chamadas classes especiais. Problematiza o conceito atual de diversidade tendo em vista a crescente presença de um novo grupo de diversos nas escolas, os estrangeiros, e propõe, a partir da leitura de Foucault sobre o direito à saúde, uma linha móvel para o entendimento da diversidade.The article considers the so called Basaglia's law that closed the asylums as a watershed in the Italian society. It regards the approach to the theme of diversity. Based on an experience of three years in the Italian schools the article examines the practice of another law that foresees the attendance by all children, normal or handicapped, in regular schools instead of special ones. It poses the problematic of the current concept of diversity and proposes from the reading of Foucault on the right to health, a mobile line for the understanding of diversity.

  11. “All now is still” : de la citation à l’œuvre dans Ruggiero and Angelica de Dante Gabriel Rossetti

    Directory of Open Access Journals (Sweden)

    Laurence ROUSSILLON

    2004-06-01

    Full Text Available Des tableaux illustrant la poésie de Dante aux sonnets commentant des tableaux d’artistes célèbres jusqu’à ses propres poèmes tableaux – œuvres hybrides où texte et image se mêlent plus qu’ils ne se côtoient – l’œuvre poétique et picturale de Dante Gabriel Rossetti est un labyrinthe d’intertextualité et une source inépuisable de réflexion sur les jeux et les enjeux de la citation. Elle est chez lui rarement à entendre dans le sens classique du terme où il s’agit de rapporter un passage d’une ...

  12. Physical start up of the Dalat nuclear research reactor with the core configuration having a central neutron trap; Khoi dong vat ly lo phan ung hat nhan Da Lat voi cau hinh vung hoat co bay notron

    Energy Technology Data Exchange (ETDEWEB)

    Hien, Pham Duy; Huy, Ngo Quang; Long, Vu Hai; Mai, Tran Khanh [Nuclear Research Inst., Da Lat (Viet Nam)

    1994-10-01

    After the reactor has reached physical criticality with the core configuration exempt from central neutron trap on 1 November 1983, the core configuration with a central neutron trap has been arranged in the reactor and the reactor has reached physical criticality with this core configuration at 17h48 on 18 December 1983. The integral worths of different control rods are determined with accuracy. 2 refs., 24 figs., 18 tabs.

  13. Physical start up of the Dalat nuclear research reactor with the core configuration exempt from neutron trap; Khoi dong vat ly lo phan ung hat nhan Da Lat voi cau hinh vung hoat khong co bay notron

    Energy Technology Data Exchange (ETDEWEB)

    Hien, Pham Duy; Huy, Ngo Quang; Long, Vu Hai; Mai, Tran Khanh [Nuclear Research Inst., Da Lat (Viet Nam)

    1994-10-01

    The nominal power of the reconstructed Dalat reactor is of 500 KW. After a meticulous preparation the Russian and Vietnamese teams have proceeded to the physical reactor start-up in November 1983 with the core configuration exempt from the neutron trap. The reactor has reached the physical criticality at 19h50 on 1 November 1983. The report delineates different steps of the start-up procedure. 2 refs., 3 figs., 7 tabs.

  14. ¿Qué otras competencias debe tener el profesorado del alumnado inmigrante? (What Other Skills Should Have Teachers of Immigrant Students? (Quelles compétences doivent avoir les professeurs des élèves immigrés? (Quais outras competências deve ter o professorado de alunos imigrantes?

    Directory of Open Access Journals (Sweden)

    Hilario Murua-Cartón

    2012-12-01

    Full Text Available ResumenEste artículo de investigación se deriva del proyectoDesarrollo de competencias específicas del profesora- do y personal de apoyo para lograr la integración del alumnado inmigrante, iniciado en el curso 2008/09, sobre las competencias que debe presentar el profe- sorado que trabaja con alumnado inmigrante en las etapas de enseñanza infantil y primaria. Se planteó un cuestionario con 35 ítems referidos a Consciencia, Actitud, Conocimiento y Destreza y Habilidades. Tam- bién contó con preguntas abiertas sobre los niveles de satisfacción, expectativas de formación, situación personal... de los encuestados. En las conclusiones se observan la falta de preparación del profesorado para trabajar con alumnado inmigrante y su predisposición para la mejora de su práctica educativa.AbstractThis research article resulting from the project Development of speci- fic competences of teachers and su- pport staff to achieve the integration of immigrant students, started in the academic year 2008/09, on the skills required from the teachers working with immigrant students in stages of early childhood in Primary Education. It raised a questionnaire with 35 items related to: Awareness, Attitude, Skills and Knowledge and Skills. Also fea- tured open questions on satisfaction levels, training expectations, personal situation, of respondents. The conclu- sions noted the lack of preparation of teachers to work with immigrant stu- dents and their willingness to improve their educational practice.RésuméCet article de recherche découle du projet Développement de compéten- ces spécifiques des professeurs et du personnel d'appui pour réussir dans l'intégration des élèves immigrés; ce projet a commencé dans le cours 2008- 2009, par rapport aux compétences que les professeurs d’enseignement enfantin et primaire doivent avoir pour travailler avec des élèves immigrés. On a proposé un questionnaire avec tren- te-cinq 35 items référés à: la conscien- ce, l'attitude, la connaissance, l'adresse et les habilités. Le test a compté aussi avec des questions ouvertes par ra- pport aux niveaux de satisfaction, les expectatives de formation, la situation personnelle des personnes interro- gées. Dans les conclusions on a obser- vé le défaut de préparation des pro- fesseurs dans le travail avec des élèves immigrés, et aussi une prédisposition par rapport à l'amélioration de leur pratique éducative.ResumoEste artigo de pesquisa se deriva do projeto Desenvolvimento de compe- tências específicas do professorado e pessoal de apoio para conseguir a in- tegração do corpo discente imigrante, iniciado no curso 2008/09, sobre as competências que deve apresentar o professorado que trabalha com corpo discente imigrante nas etapas de Ensi- no Infantil e Primária. Foi proposto um questionário com 35 itens referidos a: Consciência, Atitude, Conhecimento, Destreza e Habilidades. Também con- tou com perguntas abertas sobre os níveis de satisfação, expectativas de formação, situação pessoal... dos en- trevistados. Nas conclusões se observa a falta de preparação do professorado para trabalhar com corpo discente imi- grante, bem como sua predisposição para a melhora de sua prática educa- tiva.

  15. Hortaliças in natura ou minimamente processadas em unidades de alimentação e nutrição: quais aspectos devem ser considerados na sua aquisição? Fresh or minimally processed vegetables in foodservices: what aspects should be considered when purchasing them?

    Directory of Open Access Journals (Sweden)

    Gabriel Carvalho Degiovanni

    2010-10-01

    Full Text Available Objetivo O objetivo do estudo foi avaliar as perdas ocorridas no processamento de hortaliças in natura, comparar o custo da aquisição de hortaliças in natura e das minimamente processadas e discutir as vantagens e desvantagens da utilização destas últimas. Métodos Foram calculados fatores de correção de sete hortaliças por meio da determinação do peso bruto e do peso líquido em triplicata e o peso aferido por balança digital. Foram calculados média, desvio-padrão e coeficiente de variação. Os custos do peso bruto, considerando a correção pelo seu rendimento líquido, foram comparados aos custos das hortaliças minimamente processadas fornecidos pelo fabricante em dois períodos. Resultados Os valores da abobrinha, cenoura, chuchu e mandioquinha minimamente processados foram, respectivamente, 8,6%, 14,1%, 4,6% e 13,5% menores em relação ao custo do alimento bruto no tempo 1, mas isso não se repetiu no tempo 2, quando os alimentos in natura apresentavam menor custo. Conclusão Conclui-se que inúmeros fatores inerentes ou externos aos alimentos influenciam diretamente na magnitude das perdas durante o processamento. Os métodos de trabalho e objetivos finais de cada unidade produtora é que devem definir qual produto é o mais vantajoso, considerando que os custos são variáveis, uma vez que a produção pode ser comprometida pela sazonalidade e pela oferta e procura dos alimentos, com repercussão na gestão de qualidade da unidade.Objective The objective of the present study was to assess the losses that occur when fresh vegetables are processed, to compare the cost of purchasing fresh and minimally processed vegetables, and to discuss the advantages and disadvantages of using minimally processed food items. Methods Correction factors for seven food items were calculated by determining their gross and net weights in triplicate with a digital scale. Mean, standard deviation and variation coefficient were calculated. The costs of gross weight considering the correction for net yield were compared with the costs of minimally processed vegetables supplied by the manufacturer during two different periods. Results The costs of minimally processed zucchini, carrot, chayote and arracacha were 8.6%, 14.1%, 4.6% and 13.5% lower than their respective fresh counterparts at time 1, a fact that did not repeat itself at time 2, when these vegetables were less expensive when bought fresh. Conclusion In conclusion, numerous factors associated or not with the food directly influence the magnitude of the losses that occur during processing. The working methods and final objectives of each foodservice should define which product is more advantageous since costs vary and production can be affected by seasonality and the supply and demand of the food item, with repercussions on the quality management of the foodservice.

  16. Quais são os recentes achados clínicos sobre a associação entre depressão e suicídio? Which are the recent clinical findings regarding the association between depression and suicide?

    Directory of Open Access Journals (Sweden)

    Eduardo Chachamovich

    2009-05-01

    Full Text Available OBJETIVO: Suicídio é uma das maiores causas de mortalidade ao redor do mundo, especialmente entre indivíduos jovens. Suicídio é considerado o desfecho de um fenômeno complexo e multidimensional, e decorrente da interação de diversos fatores. A associação entre psicopatologia e suicídio tem sido largamente estudada. Dentre os diagnósticos psiquiátricos associados a suicídio, depressão maior se destaca sobremaneira. Tais achados parecem ser confirmados em diferentes desenhos metodológicos e em distintas populações. Este artigo visa a revisar sucintamente as contribuições recentes acerca das características clínicas da depressão que se encontram vinculadas a casos de suicídio. Destacam-se também os esforços de prevenção, no sentido de, ao se detectar e tratar casos de depressão em serviços gerais de saúde, diminuir o risco de suicídio. REVISÃO: Referências recentes foram identificadas e agrupadas com o intuito de ilustrar as principais contribuições acerca da interface entre depressão e suicídio. Brevemente, a revisão de literatura aberta aponta para a grande prevalência do diagnóstico de depressão maior entre os casos de comportamento suicida. Traços psicopatológicos de agressão e impulsividade parecem exercer um papel relevante no desencadeamento de atos suicidas. Estratégias de prevenção foram também revisadas nos contextos internacional e brasileiro. De modo geral, a detecção e tratamento de depressão são capazes de reduzir as taxas de suicídio. CONCLUSÃO: No campo da pesquisa sobre comportamento suicida, os estudos têm tido caráter pragmático e produziram um panorama de fatores claramente associados ao suicídio, sem, no entanto, oferecer uma amarração teórica consistente para os achados. A crescente adoção de modernas técnicas traz uma ampliação das possibilidades de investigação. Para serem clinicamente úteis, os novos conhecimentos devem possibilitar um olhar mais profundo no mundo de uma pessoa suicida, bem como a adoção de estratégias específicas de tratamento e de prevenção que fossem mais eficientes para subgrupos populacionais.OBJECTIVE: Suicide is one of the leading causes of mortality worldwide, especially among young subjects. Suicide is considered the outcome of a multidimensional and complex phenomenon, which is a result of the interaction between several factors. The association between psychopathology and suicide has been extensively investigated. Major depression plays an important role among the psychiatric diagnoses associated with suicide. This finding seems to be confirmed by different study designs, and in distinct populations. The present paper aims to briefly review the recent findings regarding the suicide-related clinical features of depression. Moreover, strategies for suicide prevention were also reviewed. REVIEW: Recent references were identified and grouped in order to illustrate the main contributions about depression and suicide. Briefly, the literature review stresses the high prevalence of major depression among subjects presenting suicide behaviors. Psychopathological traits, such as aggression and impulsivity play a relevant role in triggering suicidal behaviors. Strategies for suicide prevention were also reviewed in Brazil and internationally. In general, detection and treatment are effective in reducing suicide rates. CONCLUSION: Studies regarding suicide behaviors have had a pragmatic approach, and generated a large body of evidence about correlates of suicide. However, these studies have not been able to provide a consistent theoretical explanation for this phenomenon. The recent adoption of modern strategies represents a possibility of enhancing the research capability of such studies. In order to be clinically useful, findings should make it possible to deepen the understanding over the experience of a suicidal person, as well as to design specific strategies for prevention and treatment in population subgroups.

  17. EL DIAGNÓSTICO PSICOPATOLÓGICO: CARACTERÍSTICAS Y SUPUESTOS EPISTEMOLÓGICOS EN LOS QUE SE SUSTENTA/ PSYCHOPATHOLOGICAL DIAGNOSIS: ITS CHARACTERISTICS AND GROUNDING EPISTEMOLOGICAL ASSUMPTIONS/ O DIAGNÓSTICO PSICOPATOLÓGICO: CARACTERÍSTICAS E SUPOSTOS EPISTEMOLÓGICOS NOS QUAIS SE SUSTENTA

    Directory of Open Access Journals (Sweden)

    Dante Gabriel Duero

    2013-06-01

    Full Text Available Urgida por la necesidad de justificarla e incluirla como una rama médica, así como de otorgarle credibilidad y defender su autoridad al abordar los llamados desórdenes mentales, la profesión psiquiátrica se ha inclinado a privilegiar los modelos biológicos y conceptualizar estos fenómenos como resultados de disfunciones orgánicas. Sin embargo, en este artículo se señala que la labor del psicopatólogo supone una valoración comprensiva y biográfica de los marcos interpretativos, las acciones y la personalidad del enfermo como unidad intencional e histórica. Se reafirma la especificidad del discurso psicológico y psiquiátrico, y los supuestos de apoyo. Se discuten aspectos del diagnóstico y la labor clínica en psicopatología a la luz de la propuesta narrativa de Paul Ricoeur.

  18. Occurrence of cavernicolous ground beetles in Anhui Province, eastern China (Coleoptera, Carabidae, Trechinae).

    Science.gov (United States)

    Fang, Jie; Li, Wenbo; Tian, Mingyi

    2016-01-01

    Two new species of anophthalmic ground beetles belonging to the subfamily Trechinae are described: Cimmeritodes (Zhecimmerites) parvus Tian & Li, sp. n. and Wanoblemus wui Tian & Fang, gen. n., sp. n. Both were discovered in the limestone caves of Anhui Province in eastern China. Cimmeritodes (Zhecimmerites) parvus was found in caves Ziwei Dong, Xianren Dong and Qingtai Dong, whereas Wanoblemus wui was discovered in cave Baiyun Dong. This is the first record of cavernicolous ground beetles in Anhui Province, eastern China.

  19. Occurrence of cavernicolous ground beetles in Anhui Province, eastern China (Coleoptera, Carabidae, Trechinae

    Directory of Open Access Journals (Sweden)

    Jie Fang

    2016-10-01

    Full Text Available Two new species of anophthalmic ground beetles belonging to the subfamily Trechinae are described: Cimmeritodes (Zhecimmerites parvus Tian & Li, sp. n. and Wanoblemus wui Tian & Fang, gen. n., sp. n. Both were discovered in the limestone caves of Anhui Province in eastern China. C. (Z. parvus was found in caves Ziwei Dong, Xianren Dong and Qingtai Dong, whereas W. wui was discovered in cave Baiyun Dong. This is the first record of cavernicolous ground beetles in Anhui Province, eastern China.

  20. Botanical modulation of menopausal symptoms: Mechanisms of action?

    Science.gov (United States)

    Hajirahimkhan, Atieh; Dietz, Birgit M.; Bolton, Judy L.

    2013-01-01

    Menopausal women suffer from a variety of symptoms, including hot flashes and night sweats which can affect quality of life. Although hormone therapy (HT) has been the treatment of choice for relieving these symptoms, HT has been associated with increased breast cancer risk leading many women to search for natural, efficacious, and safe alternatives such as botanical supplements. Data from clinical trials suggesting that botanicals have efficacy for menopausal symptom relief, have been controversial and several mechanisms of action have been proposed including estrogenic, progestogenic, and serotonergic pathways. Plant extracts with potential estrogenic activities include soy, red clover, kudzu, hops, licorice, rhubarb, yam, and chasteberry. Botanicals with reported progestogenic activities are red clover, hops, yam, and chasteberry. Serotonergic mechanisms have also been proposed since women taking antidepressants often report reduction in hot flashes and night sweats. Black cohosh, kudzu, kava, licorice, and dong quai all either have reported 5-HT7 ligands or inhibit serotonin re-uptake, therefore have potential serotonergic activities. Understanding the mechanisms of action of these natural remedies used for women’s health, could lead to more efficacious formulations and to the isolation of active components which have the potential of becoming effective medications in the future. PMID:23408273

  1. Protection of Chinese herbs against Adenine-induced chronic renal ...

    African Journals Online (AJOL)

    The aim of the study is to evaluate the efficacy of Chinese herbs (Angelica sinensis, Ligusticum wallichii, Salvia miltiorrhiza, Rhizoma dioscoreae, Rhodiola crenilata, Astragalus membranaceus and Angelica sinensis) on adenine-induced chronic renal failure in rats. 30 age-matched male Wistar rats were divided into three ...

  2. Heart Toxicity Related to Herbs and Dietary Supplements: Online Table of Case Reports. Part 4 of 5.

    Science.gov (United States)

    Brown, Amy C

    2017-10-05

    The purpose of this review was to create an online research summary table of heart toxicity case reports related to dietary supplements (DS; includes herbs). Documented PubMed case reports of DS appearing to contribute to heart-related problems were used to create a "Toxic Table" that summarized the research (1966 to April, 2016, and cross-referencing). Keywords included "herb," "dietary supplement," and cardiac terms. Case reports were excluded if they were herb combinations (some exceptions), Chinese herb mixtures, teas of mixed herb contents, mushrooms, poisonous plants, self-harm (e.g. suicide), excess dose (except vitamins/minerals), drugs or illegal drugs, drug-herbal interactions, and confounders of drugs or diseases. The spectrum of heart toxicities included hypertension, hypotension, hypokalemia, bradycardia, tachycardia, arrhythmia, ventricular fibrillation, heart attack, cardiac arrest, heart failure, and death. Heart related problems were associated with approximately seven herbs: Four traditional Chinese medicine herbs - Don quai (Angelica sinensis), Jin bu huan (Lycopodium serratum), Thundergod vine or lei gong teng (Tripterygium wilfordii Hook F), and Ting kung teng (Erycibe henryi prain); one an Ayruvedic herb - Aswagandha, (Withania somnifera); and two North American herbs - blue cohosh (Caulophyllum thalictroides), and Yohimbe (Pausinystalia johimbe). Aconitum and Ephedra species are no longer sold in the United States. The DS included, but are not limited to five DS - bitter orange, caffeine, certain energy drinks, nitric oxide products, and a calming product. Six additional DS are no longer sold. Licorice was the food related to heart problems. The online "Toxic Table" forewarns clinicians, consumers and the DS industry by listing DS with case reports related to heart toxicity. It may also contribute to Phase IV post marketing surveillance to diminish adverse events that Government officials use to regulate DS.

  3. Tracking Theory Building and Use Trends in Selected LIS Journals: More Research is Needed. A review of: Kim, Sung‐Jin, and Dong Y. Jeong. “An Analysis of the Development and Use of Theory in Library and Information Science Research Articles.” Library & Information Science Research 28.4 (Sept. 2006: 548‐62.

    Directory of Open Access Journals (Sweden)

    Carol Perryman

    2007-09-01

    Full Text Available Objective ‐ The authors measure theory incidents occurring in four LIS journals between 1984‐2003 in order to examine their number and quality and to analyze them by topic. A third objective, only identified later in the text of the study, was to compare theory development and use between Korean and international journals. Research questions asked include whether LIS has its own theoretical base as a discipline, and what characteristics the theoretical framework has.Design – Bibliometric study.Setting – Journal issues selected from four LIS journals for the time span from 1984 ‐ 2003.Subjects – Two international journals, Journal of the American Society for Information Science and Technology (JASIST and Library and Information Science Research (LISR were selected based on their high ranking in the Social Sciences Citation Index (SSCI impact factors. Two Korean journals, Journal of the Korean Society for Information Management (JKSIM and Journal of the Korean Society for Library and Information Science (JKSLIS were selected.Methods ‐ After having determined a definition of theory, and identifying different levels of theory, the authors set up rules for the identification of theory incidents, which are defined as “events in which the author contributed to the development or the use of theory in his/her own paper” (550. Content analysis of 1661 research articles was performed to measure theory incidents according to working definitions. Interrater reliability was ensured by conducting independent coding for “subfield classification, identification of theory incidents, and quality measurement” (555,using a sample of 199 articles (random selection not specified, achieving 94‐97% interrater reliability. Incidents, once identified, were evaluated for quality using Dubin’s “efficiency of law” criteria, involving measures of relatedness, directionality, co‐variation, rate of change, and “profundity,” defined as the depth to which theory is incorporated into the research study.Main Results ‐ 21.79% (n=362 of the articles contained theory incidents that were analyzed and evaluated. Trend measurement indicated an overall increase, although a slight decrease was shown in the year range 1993‐2003. International journals accounted for 61.33% of theory incidents, compared to 38.67% for the Korean journals. T‐testing showed that differences in means between Korean and international journals were not statistically significant. Topical theory areas were ranked by frequency. The top five areas were shown to be nearly identical between Korean and international journals. ANOVA was performed with significant results in the difference between efficiency ratings. Conclusion – The authors find that the overall proportion of theory incidents including both theory development and use increased through the 20‐year time span examined, and that LIS has established its own theoretical framework based upon the frequency of incidents.

  4. Understanding and Controlling Living/Inorganic Interfaces to Enable Reconfigurable Switchable Materials

    Science.gov (United States)

    2018-03-01

    Mater Res. 2015;4:297–310. Invited. Dong H, Sarkes DA, Rice JJ , Hurley MM, Fu A, Stratis-Cullum D. Functionalization of living bacterial cells with...presentation. Dong H, Sarkes DA, Rice JJ , Hurley MM, Fu A, Stratis-Cullum D. Living composites: Viable bacteria-nanoparticle hybrids mediated through...surface- displayed peptides. Langmuir. Forthcoming 2017. Dong H, Sarkes DA, Rice JJ , Hurley MM, Fu A, Stratis-Cullum DN. Living bacteria/nanoparticle

  5. Polarizing Ytterbium-Doped all-Solid Photonic Bandgap Fiber with 1150 micrometers2 Effective Mode Area

    Science.gov (United States)

    2015-02-11

    RESPONSIBLE PERSON 19b. TELEPHONE NUMBER Liang Dong Fanting Kong,, Guancheng Gu,, Thomas W. Hawkins ,, Joshua Parsons, Maxwell Jones,, Christopher...Dunn,, Monica T. Kalichevsky-Dong,, Benjamin Pulford,, Iyad Dajani,, Kunimasa Saitoh,, Stephen P. Palese,, Eric Cheung,, Liang Dong c. THIS PAGE The...ytterbium-doped all-solid photonic bandgap fiber with ~1150µm2 effective mode area Fanting Kong,1,* Guancheng Gu,1 Thomas W. Hawkins ,1 Joshua Parsons

  6. An overview of herbal supplement utilization with particular emphasis on possible interactions with dental drugs and oral manifestations.

    Science.gov (United States)

    Abebe, Worku

    2003-01-01

    Herbal medication in the United States is a popular form of therapy. This paper provides an overview of the utilization of herbal supplements with particular emphasis on possible interactions with oral health drugs and oral manifestations. Herbal supplements are regulated by the Dietary Supplement Health and Education Act (DSHEA), which limits their regulation by the U.S Food and Drug Administration (FDA). A number of studies indicate that there is a progressive increase in the utilization of herbal supplements. The majority of consumers of these products are white, middle-aged women who have some college education. Many of the consumers use pharmaceutical drugs concurrently, but most do not inform their health-care providers about their use of herbal supplements. Various herbal supplements have been reported or are suspected to interact with certain oral health drugs, the most important one being 1) bromelain, cayenne, chamomile, feverfew, dong quai, eleuthro/Seberian ginseng, garlic, ginkgo, ginger, ginseng and licorice interacting with aspirin; 2) aloe latex, ephedra, ginseng, rhubarb, cascara sagrada, licorice, and senna interacting with corticosteriods; 3) kava, St. John's wort, chamomile, and valerian interacting with central nervous system (CNS) depressant drugs; and 4) herbs acting on the gastrointestinal system, altering the absorption of several orally administered drugs. Further, the use of some herbal supplements has been reported to be associated with oral manifestations, including aphthous ulcers, lip and tongue irritation, and swelling with feverfew; gingival bleeding with feverfew and ginkgo; tongue numbness with echinacea; xerostomia with St. John's wort; oral and lingual dyskinesia with kava; and salivation with yohimbe. These potential effects of herbal supplements in conjunction with factors related to regulation restrictions suggest that the use of these products may be associated with various adverse reactions that can affect oral health and

  7. Monitoring of polycyclic aromatic hydrocarbons (PAH) in food supplements containing botanicals and other ingredients on the Dutch market.

    Science.gov (United States)

    Martena, M J; Grutters, M M P; De Groot, H N; Konings, E J M; Rietjens, I M C M

    2011-01-01

    Food supplements can contain polycyclic aromatic hydrocarbons (PAH). The European Food Safety Authority (EFSA) has defined 16 priority PAH that are both genotoxic and carcinogenic and identified eight priority PAH (PAH8) or four of these (PAH4) as good indicators of the toxicity and occurrence of PAH in food. The current study aimed to determine benzo[a]pyrene and other EFSA priority PAH in different categories of food supplements containing botanicals and other ingredients. From 2003 to 2008, benzo[a]pyrene exceeded the limit of quantification (LOQ) in 553 (44%) of 1258 supplements with a lower-bound mean of 3.37 µg kg(-1). In 2008 and 2009, benzo[a]pyrene and 12 other EFSA priority PAH were determined in 333 food supplements. Benzo[a]pyrene exceeded the LOQ in 210 (63%) food supplements with a lower-bound mean of 5.26 µg kg(-1). Lower-bound mean levels for PAH4 and PAH8(-indeno[1,2,3-cd]pyrene) were 33.5 and 40.5 µg kg(-1), respectively. Supplements containing resveratrol, Ginkgo biloba, St. John's wort and propolis showed relatively high PAH4 levels in 2008 and 2009. Before 2008, supplements with these ingredients and also dong quai, green tea or valerian contained relatively high benzo[a]pyrene levels. On average, PAH4 intake resulting from food supplement use will be at the lower end of the range of contributions of main food groups to PAH4 exposure, although individual food supplements can contribute significantly to PAH4 exposure. Regular control of EFSA indicator PAH levels in food supplements may prove a way forward to reduce further the intake of PAH from food.

  8. Marketing channel choice and marketing timing of peri-urban vegetable growers in Vietnam

    NARCIS (Netherlands)

    Wiersinga, R.C.; Wijk, van M.S.; Luyen, C.H.; Hoi, P.V.

    2007-01-01

    Agriculture is an important sector in the peri-urban area of Hanoi. It supplies 62 to 80% of vegetable consumption, of which 28% comes from Dong Anh district, which borders Hanoi City. Growing vegetables is an important income source for the farmers in Dong Anh as it contributes about 30% to their

  9. Cost-effective electrostatic-sprayed SrAl2O4: Eu 2 phosphor ...

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... Department of Biomedical Engineering, Nambu University, 864-1 Wolgye-dong, Gwangsan-gu, Gwangju 506-824, Korea; Department of Electronic and Photonic Engineering, Honam University, 59-1 Seobong-dong, Gwangsan-gu, Gwangju 506-714, Korea; Department of Photonic Engineering, Chosun ...

  10. 78 FR 41995 - Actions Taken Pursuant to Executive Order 13382

    Science.gov (United States)

    2013-07-12

    ...-hour fax-on-demand service, Tel.: 202/622-0077. Background On June 28, 2005, the President, invoking... Executive Order 13382. The list of additional designees is as follows: 1. DAEDONG CREDIT BANK (a.k.a. DAE-DONG CREDIT BANK; a.k.a. DCB; a.k.a. TAEDONG CREDIT BANK), Suite 401, Potonggang Hotel, Ansan-Dong...

  11. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Dong Zhang. Articles written in Bulletin of Materials Science. Volume 34 Issue 1 February 2011 pp 25-28. Aqueous colloids of graphene oxide nanosheets by exfoliation of graphite oxide without ultrasonication · Tian-You Zhang Dong Zhang · More Details Abstract Fulltext PDF.

  12. Author Details

    African Journals Online (AJOL)

    2011) - Articles Ultraviolet Spectrophotometric Determination of Simvastain in Pharmaceutical Dosage Forms Abstract · Vol 17, No 1 (2015) - Articles Clinical assessment of the efficacy and safety of T-Angelica Herbal Tonic, a herbal beverage

  13. Teistmoodi pühadelaud - taimne jõuluroog / Ada Maltseva

    Index Scriptorium Estoniae

    Maltseva, Ada, 1970-

    2007-01-01

    Vt. ka Linnaleht : Pärnu 7. dets., lk. B2-B3, Linnaleht : Tartu 7. dets., lk. 10-11. Restorani Aed peakokk Angelica Udeküll soovitab taimetoitlastel jõuluprae valmistamisel vaadata kaunviljade ja tofu poole

  14. Une rencontre PAS comme les autres | CRDI - Centre de recherches ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    15 oct. 2010 ... Dans ce récit à la première personne, Angelica Ospina, administratrice de programmes principale au CRDI , raconte sa rencontre avec Orlando, un jeune graphiste péruvien remarquable qui lutte en première ligne contre le VIH/sida dans son pays. Angelica a fait la connaissance d'Orlando et d'autres ...

  15. Dzūkijos nacionalinio parko Liškiavos botanikos sodas: retų ir nykstančių augalų rūšių natūralizacijos galimybės

    OpenAIRE

    Baranauskas, Alius

    2005-01-01

    PAPER The possibilities of naturalization of rare and vanishing plants’ species are surveyed in master’s study The subject of research - The botanical gardens of Liskiava with the rare and vanishing plants’ species cultured and naturalized there. Objective of the research – Naturalized species of the plants: Turk’s-cap (Lilium martagon), medicinal angelica (Angelica archangelica), perennial satinflower (Lunaria rediviva), and ivy bedstraw (Hedera helix). Also the naturalization in site of rar...

  16. Risk-taking behaviour ofCape Peninsula high-school students

    African Journals Online (AJOL)

    behaviour alDong high-school students in the. Cape Peninsula ... Knonenbelt - personal communication). South Africa has ..... vision and film violence increases physical aggression ... violence in the media; revising firearm legislation and.

  17. Optimizing culture medium for debittering constitutive enzyme ...

    African Journals Online (AJOL)

    STORAGESEVER

    2010-08-02

    Aug 2, 2010 ... enzyme naringinase production by Aspergillus oryzae. JMU316. Dong-xiao .... even though industrial applications of naringinase are becoming more and ... guidance for industry. MATERIALS AND ..... For economic reasons,.

  18. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Fang Dong1 Jiang Chenning1 Zhu Ting1 Yang Jinming1. Department of Pharmaceutical Engineering, School of Chemistry and Chemical Engineering, Yancheng Teachers University, 50 Kai Fang Da Dao, Yancheng 224002, Jiangsu, P. R. China ...

  19. 75 FR 61246 - Additional Identifying Information Associated With Persons Whose Property and Interests in...

    Science.gov (United States)

    2010-10-04

    ... situation in North Korea. Section 1 of the Order blocks, with certain exceptions, all property and interests...), Sosong Street, Kyongrim-Dong, Pyongyang, Korea, North; Changgwang Street, Pyongyang, Korea, North [DPRK...

  20. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Dong Jun Jee1 Tuo Yeong Lee1 Nathaniel Zhi-Wei Leon1. Department of Mathematics, Statistics and Computing, NUS High School of Mathematics and Science, 20 Clementi Avenue 1, Singapore 129957, Republic of Singapore ...

  1. 76 FR 11512 - In the Matter of Certain Liquid Crystal Display Devices, Products Containing Same, and Methods...

    Science.gov (United States)

    2011-03-02

    ..., Taipei 114, Taiwan. Haier America Trading LLC, 1356 Broadway, New York, NY 10018. Haier Group Company, 1 Haier Road, Hi-Tech Zone, Qingdao 266101, China. LG Electronics Inc., LG Twin Towers 20, Yoido-dong...

  2. Structures and electronic properties of WmCun (n + m ≤ 7) clusters

    Indian Academy of Sciences (India)

    MS received 2 May 2017; accepted 12 June 2017; published online 29 March 2018 ... ing technology by Dong [30], revealing that graphene reacts ..... Size dependence of binding energies per atom for the lowest energy structures of WmCun ...

  3. A mixed Ni(II) ionic complex containing V-shaped water trimer ...

    Indian Academy of Sciences (India)

    aDepartment of Chemical Engineering, Sunchon National University, 315 Maegok Dong, ... bMaterials Chemistry Division, School of Advanced Sciences, VIT University, Vellore 632014, ..... Metal Carboxylates, Ph.D. Thesis, Indian Institute.

  4. Fractional M-band dual tree complex wavelet transform for digital ...

    Indian Academy of Sciences (India)

    image fusion for copy protection or water marking robust tagging applications. They considered ..... to enhance the performance and security of the images. Most of the SVD .... J. Network Computer Applications 24(4): 167–173. Dong Zheng ...

  5. Effect of process parameters on coating composition of cathodic ...

    Indian Academy of Sciences (India)

    10

    comprising of carbon nanostructure and copper oxide are formed on the copper. ... can lead to the growth of oxide film and be named micro arc oxidation (MAO) ...... A. Yerokhin, X. Li, H. Dong, and A. Matthews, Surface characterisation of DC.

  6. Korea keele õpetamisest / Angelina Tšaikovskaja

    Index Scriptorium Estoniae

    Tšaikovskaja, Angelina

    1999-01-01

    Tallinna Pedagoogikaülikooli külastas 7. dets. 1999 Korea Vabariigi suursaadik Helsingis Dong-chil Yang, kes tundis huvi idamaade keelte õpetamise vastu TPÜ-s ja lubas toetada korea keele õpetamist ülikoolis

  7. Journal of Astrophysics and Astronomy | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    2016-01-27

    Jan 27, 2016 ... You-Dong Hu. Articles written in Journal of Astrophysics and Astronomy. Volume 35 Issue 3 September 2014 pp 423-427 Part V: Black Holes (or Binary Black Holes) in Blazars. Joint Spectral Analysis for Early Bright X-ray Flares of -Ray Bursts with Swift BAT and XRT Data · Fang-Kun Peng You-Dong Hu ...

  8. Portugal and Spain entering the Common Market: Their industrial competitiveness revisited

    OpenAIRE

    Donges, Jürgen B.; Schatz, Klaus-Werner

    1985-01-01

    The purpose of this paper is to assess the overall position as well as the relative strength and weakness of the Iberian manufacturing industries within an enlarged Community. Earlier studies of the authors (Donges, Schatzf 1980; Donges et al., 1982) are up-dated and extended to cover the bilateral trade relations between Portugal and Spain. Following a recapitulation of the major trade patterns of the Iberian countries, we examine the nature of their specialization, both with regard to the E...

  9. Wall Street som kreationistisk forkynder

    DEFF Research Database (Denmark)

    Ekman, Susanne

    2016-01-01

    Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong......Artiklen gennemgår Karen Hos etnografi om Wall Street: "Liquidated: An ethnography of Wall Street" set i lyset af den offentlige debat vedrørende Goldman Sachs opkøb af Dong...

  10. Changing patient safety culture in China: a case study of an experimental Chinese hospital from a comparative perspective

    OpenAIRE

    Xu XP; Deng DN; Gu YH; Ng CS; Cai X; Xu J; Zhang XS; Ke DG; Yu QH; Chan CK

    2018-01-01

    Xiao Ping Xu,* Dong Ning Deng,* Yong Hong Gu, Chui Shan Ng, Xiao Cai, Jun Xu, Xin Shi Zhang, Dong Ge Ke, Qian Hui Yu, Chi Kuen Chan Clinical Service Department, The University of Hong Kong - Shenzhen Hospital, Shenzhen, Guangdong, People’s Republic of China *These authors contributed equally to this work Background: The World Health Organization highlights that patient safety interventions are not lacking but that the local context affects their successful implementation. Increasing att...

  11. Effect of progressive drought stress on growth, leaf gas exchange, and antioxidant production in two maize cultivars.

    Science.gov (United States)

    Anjum, Shakeel Ahmad; Tanveer, Mohsin; Ashraf, Umair; Hussain, Saddam; Shahzad, Babar; Khan, Imran; Wang, Longchang

    2016-09-01

    Drought stress is one of the major environmental factors responsible for reduction in crop productivity. In the present study, responses of two maize cultivars (Rung Nong 35 and Dong Dan 80) were examined to explicate the growth, yield, leaf gas exchange, leaf water contents, osmolyte accumulation, membrane lipid peroxidation, and antioxidant activity under progressive drought stress. Maize cultivars were subjected to varying field capacities (FC) viz., well-watered (80 % FC) and drought-stressed (35 % FC) at 45 days after sowing. The effects of drought stress were analyzed at 5, 10, 15, 20, ad 25 days after drought stress (DAS) imposition. Under prolonged drought stress, Rung Nong 35 exhibited higher reduction in growth and yield as compared to Dong Dan 80. Maize cultivar Dong Dan 80 showed higher leaf relative water content (RWC), free proline, and total carbohydrate accumulation than Run Nong 35. Malondialdehyde (MDA) and superoxide anion were increased with prolongation of drought stress, with higher rates in cultivar Run Nong 35 than cultivar Dong Dan 80. Higher production of superoxide dismutase (SOD), peroxidase (POD), and catalase (CAT) and glutathione reductase (GR) resulted in improved growth and yield in Dong Dan 80. Overall, the cultivar Dong Dan 80 was better able to resist the detrimental effects of progressive drought stress as indicated by better growth and yield due to higher antioxidant enzymes, reduced lipid peroxidation, better accumulation of osmolytes, and maintenance of tissue water contents.

  12. 15 CFR 995.3 - Availability of other publications.

    Science.gov (United States)

    2010-01-01

    ... the International Hydrographic Bureau, 4 quai Antoine 1er, B.P. 445, MC 98011 MONACO CEDEX; telephone... International Hydrographic Bureau, 4 quai Antoine 1er, B.P. 445, MC 98011 MONACO CEDEX; telephone: (377) 93.10...

  13. Soojalt sojast / Ülle Hõbemägi

    Index Scriptorium Estoniae

    Hõbemägi, Ülle

    2008-01-01

    Sojast, sojatoodetest ning sojatoitudest räägivad aroomterapeut ja massöör Marge Teder, Soya Foods Baltic OÜ müügidirektor Meeli Matsalu, tudeng ja taimetoitlane Loore-Emilie Raav ning Angelica Udeküll

  14. Varatrükise fragmentide leiust läbi oletuste atribueerimiseni / Rene Haljasmäe

    Index Scriptorium Estoniae

    Haljasmäe, Rene, 1973-

    2009-01-01

    TLÜAR-i kogu täienes kahe inkunaablilehega. Lehed leiti Angelo Carletti di Chivasso "Summa angelica de casibus conscientiae" kaante vahelt, mis valmis Nürnbergis Anton Kobergeri trükikojas 28.08.1488. Tegemist on 48-realise palveraamatu lehekülgede ning 1485. a trükitud Piibli leheküljega

  15. 76 FR 55909 - Ocean Transportation Intermediary License; Applicants

    Science.gov (United States)

    2011-09-09

    ..., LLC dba AIM Global Logistics (NVO & OFF), 6402 Teluco Street, Houston, TX 77055, Officer: Angelica Garcia-Dunn, Manager/President/Treasurer (Qualifying Individual), Application Type: New OFF & NVO License... Individual), Application Type: Name Change. BestOcean Worldwide Logistics, Inc. (NVO & OFF), 1300 Valley...

  16. Short range attraction of Ceratitis capitata (Diptera: Tephritidae) sterile males to six commercially available plant essential oils

    Science.gov (United States)

    Plant essential oils have a number of roles in insect pest management. For male Ceratitis capitata, this includes use of angelica seed oil as long range attractants and ginger root oil as aromatherapy, which is exposure to sterile males to increase mating success. Neither of these plants are hosts f...

  17. 76 FR 72164 - Circular Welded Carbon-Quality Steel Pipe From India, the Sultanate of Oman, the United Arab...

    Science.gov (United States)

    2011-11-22

    ...-811] Circular Welded Carbon-Quality Steel Pipe From India, the Sultanate of Oman, the United Arab... Emirates, and Vietnam), or Angelica Mendoza (Oman), AD/CVD Operations, Office 7, Import Administration... Sultanate of Oman (Oman), the United Arab Emirates (UAE), and the Socialist Republic of Vietnam (Vietnam...

  18. Incorporating Technology in Teaching Musical Instruments

    Science.gov (United States)

    Prodan, Angelica

    2017-01-01

    After discussing some of the drawbacks of using Skype for long distance music lessons, Angelica Prodan describes three different types of Artificial Reality (Virtual Reality, Augmented Reality and Mixed or Merged Reality). She goes on to describe the beneficial applications of technology, with results otherwise impossible to achieve in areas such…

  19. Pollinator preferences and flower constancy: is it adaptive for plants to manipulate them?

    Czech Academy of Sciences Publication Activity Database

    Janovský, Zdeněk; Smyčka, J.; Smyčková, M.; Herben, Tomáš

    2017-01-01

    Roč. 121, č. 3 (2017), s. 475-483 ISSN 0024-4066 R&D Projects: GA ČR GB14-36079G Institutional support: RVO:67985939 Keywords : Achillea millefolium * Angelica sylvestris * floral evolution Subject RIV: EH - Ecology, Behaviour OBOR OECD: Ecology Impact factor: 2.288, year: 2016

  20. Drug: D09063 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available 9], Jujube [DR:D06758], Ginger [DR:D06744], Glycyrrhiza [DR:D04365], Japanese angelica root [DR:D06768], Sac... D09063 Formula ... Drug Kigikenchuto Cinnamon bark [DR:D06712], Peony root [DR:D0673

  1. author's correction 1..1

    Indian Academy of Sciences (India)

    J. Genet. 89, e25Ye29 (http://www.ias.ac.in/jgenet/OnlineResources/90/e25.pdf). In table 1, for locus Aaz1, the core motif should be (ACAT)8 ATAAA(TG)6 and not (ACAT)8. Genetic polymorphism of serotonin transporter 5-HTTLPR: involvement in smoking behaviour. Maria Angelica Ehara Watanabe, Sandra Odebrechet ...

  2. Revista de Documentacao de Estudos em Linguistica Teorica e Aplicada (DELTA): Novos Estudos em Gamatica Gerativa, 2001 (Journal of Documentary Studies in Theoretical and Applied Linguistics [DELTA]: New Studies in Generative Grammar, 2001).

    Science.gov (United States)

    Barbara, Leila, Ed.; Rajagopalan, Kanavillil, Ed.

    2001-01-01

    These two issues of volume 17, include the following articles: "The Competing Motivation Model in the Functional Domains of Negation" (M. Angelica Furtado da Cunha); "Discursive Resonance and Politeness in Reading and Writing Practices" (Silvana Serrani Infante); "The Acquisition of Relative Clauses in Brazilian…

  3. Guo et al., Afr J Tradit Complement Altern Med., (2018) 15 (1): 1-10 ...

    African Journals Online (AJOL)

    user

    2017-12-29

    Dec 29, 2017 ... PD rats exhibited left and right (especially left) lateral rotation in a head-to-tail state. ... Note: * p < 0.01, before treatment vs after treatment in the treatment .... replenish the kidney and essence and nourish the brain; Angelica, ...

  4. Design and Flood Control Assessment of 5MWp Fishing and Photovoltaic Power Project in Xinghua City

    Science.gov (United States)

    Guo, Liuchao; Hu, Xiaodong; Su, Yuyan; Wu, Peipei; Weng, Songgan

    2017-12-01

    In order to reduce coal consumption in Jiangsu Province and develop new energy sources, considering on the distribution of geology, solar energy resources, traffic and grid connection in Xinghua City, the aim is to determine the configuration of photovoltaic modules and photovoltaic array tracking mode, design photovoltaic array and layout scheme. But the project is a wading project, it is built in Dong Tan Lake polder I115, it needs scientific and reasonable evaluation to the effect of Dong Tan Lake’s flood storage and discharge. The results can provide guidance for similar engineering’s design.

  5. Parameter optimization using GA in SVM to predict damage level of non-reshaped berm breakwater.

    Digital Repository Service at National Institute of Oceanography (India)

    Harish, N.; Lokesha.; Mandal, S.; Rao, S.; Patil, S.G.

    tools, such as Artificial Neural Network (ANN), Support Vector Machine (SVM), Adaptive Neuro Fuzzy Inference System (ANFIS), etc., are successfully used in different fields (Kazperkiewiecz et al 1995, Voga and Belchior 2006, Dong et al 2005). Also... Balas C.E., Koc M.L. and Tur R.(2010) ‘’Artificial neural networks based on principal component analysis, fuzzy systems and fuzzy neural networks for preliminary design of rubble mound breakwaters’’, Applied Ocean Research, 32, 425 – 433. Dong B., Cao C...

  6. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 128; Issue 6. Triflic Anhydride-Mediated Beckmann Rearrangement Reaction of Β-Oximyl Amides: Access to 5-Iminooxazolines. MANGFEI YU QIAN ZHANG JIA WANG PENG HUANG PENGFEI YAN RUI ZHANG DEWEN DONG. Regular Article Volume 128 Issue 6 ...

  7. Evaluation of effectiveness in a novel wound healing ointment ...

    African Journals Online (AJOL)

    Evaluation of effectiveness in a novel wound healing ointment-crocodile oil burn ointment. Hua-Liang Li, Yi-Tao Deng, Zi-Ran Zhang, Qi-Rui Fu, Ya-Hui Zheng, Xing-Mei Cao, Jing Nie, Li-Wen Fu, Li-Ping Chen, You-Xiong Xiong, Dong-Yan Shen, Qing-Xi Chen ...

  8. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Jiandong Wu1 Xiaolei Jin1 Yang Zhao1 Qing Dong1 Haiyang Jiang1 Qing Ma1. Key Laboratory of Crop Biology of Anhui Province, School of Life Sciences, Anhui Agricultural University, Hefei 230036, People's Republic of China ...

  9. Zhu Qing Wang

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. Zhu Qing Wang. Articles written in Journal of Chemical Sciences. Volume 121 Issue 4 July 2009 pp 543-548. Highly sensitive optical chemosensor for the detection of Cu using a rhodamine B spirolatam · Gen Hua Wu Dong Xiang Wang Da Yu Wu Yuan Gao Zhu Qing Wang.

  10. Journal of Genetics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Yu-Song Guo Zhong-Duo Wang Cheng-Zhong Yan Yu-Lan Zhang Jin-Nan Zheng Yuan-Min Xu Tao Du Chu-Wu Liu · More Details Fulltext PDF ... Aifu Yang Dapeng Sun Shikai Liu Ying Dong Zhong Chen Zunchun Zhou · More Details Fulltext ...

  11. Non-linearity parameter of binary liquid mixtures at elevated pressures

    Indian Academy of Sciences (India)

    parameter B/A of four binary liquid mixtures using Tong and Dong equation at high pressures and .... in general as regular or ideal as no recognized association takes place between the unlike molecules. In this case ... Using the definition and.

  12. Vrutshenõ prizõ 25-go festivalja fantastiki

    Index Scriptorium Estoniae

    2007-01-01

    Brrüsseli ulmefilmide rahvusvahelise festivali peapreemia - Kuldse Ronga (Golden Raven) võitis korealase Joon-ho Bongi film "The Host", Hõbedase Ronga said korealase Dong-ho Cho "Rahutu" ("The Restless") ja uus-meremaalase Jonathan Kingi "Must lammas" ("Black Sheep")

  13. Anti-anxiety effect of methanol extract of Pericarpium zanthoxyli ...

    African Journals Online (AJOL)

    the elevated plus maze test, suggesting that it has significant anti-anxiety activity. Furthermore, the ... Kyung-Dong Oriental Market, Seoul, Republic of. Korea. They were ... on which the mouse placed all four paws; rearing was defined as each ...

  14. Selecting Actuator Configuration for a Benson Boiler

    DEFF Research Database (Denmark)

    Kragelund, Martin Nygaard; Leth, John-Josef; Wisniewski, Rafal

    2009-01-01

    with particular focus on a boiler in a power plant operated by DONG Energy - a Danish energy supplier. The problem has been reformulated using mathematic notions from economics. The selection of actuator configuration has been limited to the fuel system which in the considered plant consists of three different...

  15. Evolution of the defensin-like gene family in grass genomes

    Indian Academy of Sciences (India)

    . Jiandong Wu, Xiaolei Jing, Yang Zhao, Qing Dong, Haiyang Jiang and Qing Ma. J. Genet. 95, 53–62. Table 1. Information about DEFL genes in B. distachyon, O. sativa, S. bicolor and Z. mays. Species. Gene name. Gene identifer. ORF (aa).

  16. Probing High School Students' Cognitive Structures and Key Areas of Learning Difficulties on Ethanoic Acid Using the Flow Map Method

    Science.gov (United States)

    Zhou, Qing; Wang, Tingting; Zheng, Qi

    2015-01-01

    The purpose of this study was primarily to explore high school students' cognitive structures and to identify their learning difficulties on ethanoic acid through the flow map method. The subjects of this study were 30 grade 1 students from Dong Yuan Road Senior High School in Xi'an, China. The interviews were conducted a week after the students…

  17. 76 FR 51396 - Certain Light-Emitting Diodes and Products Containing Same; Notice of Institution of Investigation

    Science.gov (United States)

    2011-08-18

    ... 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of Samsung LED Co., Ltd. of Korea and Samsung LED America, Inc. of Atlanta, Georgia. The complaint alleges violations of section 337... shall be served: (a) The complainants are: Samsung LED Co., Ltd., 314, Maetan 3-Dong, Yeongtong-gu...

  18. 76 FR 52348 - Certain Light-Emitting Diodes and Products Containing Same; Corrected Notice of Institution of...

    Science.gov (United States)

    2011-08-22

    ... section 337 of the Tariff Act of 1930, as amended, 19 U.S.C. 1337, on behalf of Samsung LED Co., Ltd. of Korea and Samsung LED America, Inc. of Atlanta, Georgia. The complaint alleges violations of section 337... shall be served: (a) The complainants are: Samsung LED Co., Ltd., 314, Maetan 3-Dong, Yeongtong-gu...

  19. Characterization and photocatalytic activity of boron-doped TiO2 thin ...

    Indian Academy of Sciences (India)

    Wintec

    Chen Daimai, Wang Dong Yang and Jiang Zhongyi 2006 Ind. Eng. Chem. 45 4110. Cheng Jen-hao 2003 A study on photocatalytic oxidation of aque- ous chlorobenzene solution by nanostructured film of TiO2,. Master Thesis, National Sun Yat-Sen University, Taiwan. Deki S, Henin Yu Yu Ko, Fujita T, Akamatsu K, Mizuhata ...

  20. The high-resolution global SST forecast set of the CSIR

    CSIR Research Space (South Africa)

    Landman, WA

    2011-09-01

    Full Text Available -RESOLUTION GLOBAL SST FORECAST SET OF THE CSIR Willem A. Landman Council for Scientific and Industrial Research, P. O. Box 395, Pretoria, 0001, South Africa David G. DeWitt and Dong-Eun Lee International Research Institute for Climate and Society, Lamont...

  1. Optimized system for plant regeneration of watermelon (Citrullus ...

    African Journals Online (AJOL)

    Jane

    2011-08-29

    Aug 29, 2011 ... Table 1. MS basal medium containing ten combinations of IAA and BA. Hormone ..... 3: Ca-Ci. New Delhi: Publication and Information Directorate, CSIR; 606-609. Blackmon WJ ... Dong JZ, Jia SR (1991). High efficiency plant ...

  2. China’s Energy Insecurity and the South China Sea Dispute

    Science.gov (United States)

    2011-03-24

    Policy Since 1938 (New York, NY: Penguin Books, 1997), 123-126. 32 Ian Bremmer, “Gathering Storm: America and China in 2020,” World Affairs, 58. 32...from-the- asean-china- fta / (accessed March 21, 2020). 35 73 Jing-dong Yuan, China-ASEAN Relations: Perspectives, Prospects, and Implications for

  3. Latvijas gaze

    International Nuclear Information System (INIS)

    1994-04-01

    A collection of photocopies of materials (such as overheads etc.) used at a seminar (organized by the Board of Directors of the company designated ''Latvijas Gaze'' in connection with The National Oil and Gas Company of Denmark, DONG) comprising an analysis of training needs with regard to marketing of gas technology and consultancy to countries in Europe, especially with regard to Latvia. (AB)

  4. Genetic diversity analysis of five cattle breeds native to China using ...

    Indian Academy of Sciences (India)

    Unknown

    This work was supported by Department of Education of Shan- dong Province of China Foundation (No. J04C11). References. Barendse W., Armitage S. M. and Kossarek L. M. 1994 A gene- tic linkage map of the bovine genome. Nature Genetics 6,. 227–235. Barker J. S. F. 1994 A global protocol for determining genetic.

  5. Anisotropic in-Plane Thermal Conductivity Observed in Few-Layer Black Phosphorus

    Science.gov (United States)

    2015-10-16

    Low, T. et al. Tunable optical properties of multilayers black phosphorus. Phys. Rev. B 90, 075434 (2014). 23. Lam, K., Dong , Z. & Guo, J. Performance...transistors. ACS Nano 9, 4138–4145 (2015). 46. Wu, J., Mao , N., Xie, L., Xu, H. & Zhang, J. Identifying the crystalline orientation of black phosphorus using

  6. A Canon, a Norm and an Attitude--Ideological Dimensions in Foreign Language Education in China.

    Science.gov (United States)

    Feng, Anwei

    An examination of China's policy, "making the ancient serve the present and foreign things serve China," introduced by Mao Ze-dong, is intended to provoke further discussion of the ideological dimension of foreign language education (FLE) in China. Some observers suggest that this has been an important guiding doctrine in FLE since 1949,…

  7. Comment obtenir des fonds pour la prévention des maladies non ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... une analyse des parties prenantes, une analyse documentaire et des entrevues semi-structurées. Les participants à l'étude proviendront d'organismes gouvernementaux, d'organismes de développement, d'ONG locales et internationales, de groupes professionnels et d'établissements d'enseignement et de recherche.

  8. Reference: 356 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available 006 Mar Plant molecular biology Deng Xingwang|Dong Li|Wang Lei|Xue Yongbiao|Zhang Yansheng|Zhang Yu'e ...ein CEGENDUO negatively regulates auxin-mediated lateral root formation in Arabidopsis. 4 599-615 16525894 2

  9. Fermentation characteristics of Korean pear (Pyrus pyrifolia Nakai ...

    African Journals Online (AJOL)

    USER

    2010-08-30

    Aug 30, 2010 ... Dong Chung Kim1, Hee Jeong Chae2,3 and Man-Jin In1*. 1Department of Human ... 0.3% proteins and 0.2% lipids (Hwang and Park, 2006). It is primarily consumed as ..... Khan SH, Ansari FA (2007). Probiotics – the friendly ...

  10. A new alpheid shrimp (Crustacea: Decapoda: Alpheidae) from South Vietnam

    NARCIS (Netherlands)

    Nguyên Van Xuân,

    2001-01-01

    A new alpheid shrimp, Thuylamea camelus gen. nov. & spec. nov., from Dong Hoa, a coastal community of Can Gio district, and northwest of Vung Tau (Cap St. Jacques), Vietnam, is described and illustrated. The new genus appears not to be closely related to any of the previously described genera. It

  11. Influence of pesticide information sources on citrus farmer's knowledge, perception and practices in pest management, Mekong Delta, Vietnam

    NARCIS (Netherlands)

    Mele, van P.; Hai, T.V.; Thas, O.; Huis, van A.

    2002-01-01

    In 1998-99, about 150 citrus farmers and 120 pesticide sellers were interviewed in Can Tho and Dong Thap province, Mekong Delta, Vietnam. Media, pesticide sellers and extension staff had different influences on farmers' pest perception and management practices depending on the region and intensity

  12. 76 FR 40746 - In the Matter of Certain Light-Emitting Diodes and Products Containing Same; Notice of...

    Science.gov (United States)

    2011-07-11

    ... served: Samsung Electronics Co., Ltd., 416 Maetan-dong, Yeongtong-gu, Suwon-si, Gyeonggi-do 443-742, Korea. Samsung Electronics America, Inc., 85 Challenger Road, Ridgefield Park, NJ 07660. Samsung LED Co., Ltd., 206, Cheomdansaneop Road, Yeongtong-gu, Suwon City, Gyeonggi Province 443-743, Korea. Samsung...

  13. JCSC_128_12_1855_1860_SI.doc

    Indian Academy of Sciences (India)

    Choline-based biodegradable ionic liquid catalyst for Mannich-type reaction. PENG HUANa, HU YULINb, XING RONGa, b and FANG DONG*,a, b. a College of Chemical Engineering, Nanjing Tech University, Nanjing 210009, P.R. China. bSchool of Chemistry & Environmental Engineering, Yancheng Teachers University, ...

  14. Genomewide identification, classification and analysis of NAC type ...

    Indian Academy of Sciences (India)

    Supplementary data: Genomewide identification, classification and analysis of NAC type gene family in maize. Xiaojian Peng, Yang Zhao, Xiaoming Li, Min Wu, Wenbo Chai, Lei Sheng, Yu Wang, Qing Dong,. Haiyang Jiang and Beijiu Cheng. J. Genet. 94, 377–390. Table 1. Detailed information of NAC proteins in maize.

  15. Pt-Pd nanoelectrocatalyst of ultralow Pt content for the oxidation of ...

    Indian Academy of Sciences (India)

    formic acid oxidation on Pt4Pd96 nanoparticles. Keywords. ..... Choi J H, Jeong K J, Dong Y, Han J, Lim T H, Lee J S ... Rhee C K, Kim B J, Ham C, Kim Y J, Song K and Kwon ... Wang R, Liao S and Ji S 2008 J. Power Sources 180 205. 18.

  16. Research Article Special Issue

    African Journals Online (AJOL)

    2017-10-05

    Oct 5, 2017 ... ... control systems, dynamic systems and time-series prediction [3-7]. ..... MATLAB 7.11 running on a Core i5, 2.6GHz CPU with 4G RAM ..... [7] Dong F, Lei X, Chou W. A dynamic model and control method for a two-axis ...

  17. Proceedings – Mathematical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Jung Rye Lee1 Choonkil Park2 Dong Yun Shin3. Department of Mathematics, Daejin University, Kyeonggi 487-711, Korea; Research Institute for Natural Sciences, Hanyang University, Seoul 133-791, Korea; Department of Mathematics, University of Seoul, Seoul 130-743, Korea ...

  18. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences. YU-HUI HOU. Articles written in Journal of Chemical Sciences. Volume 130 Issue 1 January 2018 pp 6. Efficient click reaction towards novel sulfonamide hybrids by molecular hybridization strategy as antiproliferative agents · DONG-JUN FU YU-HUI HOU SAI-YANG ZHANG ...

  19. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Soo-Dong Woo1 Jae Young Choi2 Yeon Ho Je2 Byung Rae Jin3. Department of Plant Medicine, College of Agriculture, Life and Environment Sciences, Chungbuk National University, Cheongju 361-763, Korea; School of Agricultural Biotechnology, College of Agriculture and Life Sciences, Seoul National University, Seoul ...

  20. In situ rumen degradability characteristics of rice straw, soybean ...

    African Journals Online (AJOL)

    In situ rumen degradability characteristics of rice straw, soybean curd residue and peppermint (Mentha piperita) in Hanwoo steer (Bos Taurus coreanae). Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon ...

  1. Browse Title Index

    African Journals Online (AJOL)

    Items 6201 - 6250 of 11090 ... Byong Tae Jeon, KyoungHoon Kim, Sung Jin Kim, Na Yeon Kim, Jae Hyun Park, Dong Hyun Kim, Mi Rae Oh, Sang Ho Moon. Vol 10, No 65 (2011), In vitro activity of certain antimicrobial agents in combination with Augouardia letestii hexane extracts against methicillin-resistant Staphylococcus ...

  2. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 32; Issue 4. Molecular cloning and expression of the C-terminus of spider flagelliform silk protein from Araneus ventricosus. Kwang Sik Lee Bo Yeon Kim Yeon Ho Je Soo Dong Woo Hung Dae Sohn Byung Rae Jin. Articles Volume 32 Issue 4 June 2007 pp 705-712 ...

  3. Deep Tunnel for Regulating Combined Sewer Overflow Pollution and Flood Disaster: A Case Study in Guangzhou City, China

    Directory of Open Access Journals (Sweden)

    Haichun Wu

    2016-08-01

    Full Text Available The DongHaoChong (DHC basin is located in the central city zone of Guangzhou City, China. Owing to the high density of buildings and low quality of the drainage pipe network in the city, diversion of rain and sewage is difficult. Waterlogging occurs frequently and combined sewer overflow (CSO pollution is a serious problem during the rainy season. Therefore, a deep tunnel for the DongHaoChong basin has been planned and its construction is currently underway. An urban rainstorm model for the DongHaoChong basin was developed on the basis of the Storm Water Management Model (SWMM, and both the interception effect of CSO pollution and the degree of mitigation of flood were analyzed. Reasonable scenarios for the deep tunnel in terms of rainstorms with different design recurrence periods were evaluated. From the viewpoints of preventing rainstorm waterlogging disasters and protecting water quality in the region downstream of DongHaoChong River, the river flood control and drainage capacities of the region were improved to a 2-year rainstorm design recurrence period by the construction of the deep tunnel. Furthermore, the main pollutant load of the CSO is expected to be reduced by about 30%–40%.

  4. Helen Mirren krooniti Veneetsias kuningannaks / Triin Tael

    Index Scriptorium Estoniae

    Tael, Triin

    2006-01-01

    Näitleja võitis parima naisnäitleja auhinna Elizabet II rolliga Stephen Frears'i filmis "Kuninganna" ("The Queen"). Parima filmi peaauhind Kuldlõvi läks Hiina režissööri Jia Zhang-Ke filmile "Vaikelu" ("Dong"). Ka teistest Veneetsia 63. filmifestivali võitjatest

  5. 75 FR 21638 - Government-Owned Inventions; Availability for Licensing

    Science.gov (United States)

    2010-04-26

    ... been shown to play a role in bone morphogenesis, cardiovascular tissue generation, immune regulation... tissue generation. Means of studying the role of SMAD7 in immune regulation. Inventors: Marilyn Diaz (NIEHS). Related Publication: Dong C, Zhu S, Wang T, Yoon W, Li Z, Alvarez RJ, Dijke P, White B, Wigley...

  6. New Horizons in Education, 2003.

    Science.gov (United States)

    Ho, Kwok Keung, Ed.

    2003-01-01

    This journal, written in English and Chinese, includes the following papers: "Values for Creativity: A Study among Undergraduates in Hong Kong and Guangzhou" (Xia Dong Yue and Kok Leung); "The Present Situation of Family Education at the Turn of the Century: An Investigation in Three South-Eastern Provinces in China" (Feng…

  7. Study of Cu-doping effects on magnetic properties of Fe-doped ZnO ...

    Indian Academy of Sciences (India)

    Administrator

    To take into account the random distribution of ... and spin–orbit interaction were taken into account. .... Lee H J, Jeong S-Y, Ryong Cho C and Hong Park C 2002 Appl. Phys. Lett. ... Zhang Hua-Wei, Wei Zhi-Ren, Li Zhi-Qiang and Dong Guo-Yi.

  8. Pramana – Journal of Physics | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Y J Jeon1 M Jamil1 2 Hyo-Dong Lee3 J T Rhee2. Liquid Crystal Research Center, Konkuk University, Seoul 143-701, Korea; IAP, High Energy Physics Laboratory, Department of Physics, Konkuk University, Seoul 143-701, Korea; Korean Mingok Leadership Academy, Hoengseong-gun, Gangwon-do, 225-823, Korea ...

  9. supp11a.doc

    Indian Academy of Sciences (India)

    aDepartment of Chemical Engineering, Sunchon National University, 315 Maegok Dong, Suncheon 540-742, Chonnam, South Korea. bMaterials Chemistry Division, School of Advanced Sciences, VIT University, Vellore 632014, Tamilnadu, India. E-mail: ismoon@sunchon.ac.kr. Figure S1. FT-IR spectrum of compound 1.

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Division of Advanced Materials Engineering, Hydrogen & Fuel Cell Research Center, Engineering Research Institute, Chonbuk National University, 664-14 Deokjin-Dong 1Ga Deokjin-Gu Jeonju Jeonbuk, 561-756, South Korea; Department of Materials Engineering, Graduate School, Chonbuk National University, 664-14 ...

  11. The prevalence and diversity of intestinal parasitic infections in humans and domestic animals in a rural Cambodian village

    DEFF Research Database (Denmark)

    Schär, Fabian; Inpankaew, Tawin; Traub, Rebecca J.

    2014-01-01

    In Cambodia, intestinal parasitic infections are prevalent in humans and particularly in children. Yet, information on potentially zoonotic parasites in animal reservoir hosts is lacking. In May 2012, faecal samples from 218 humans, 94 dogs and 76 pigs were collected from 67 households in Dong vi...

  12. Flow Modulation and Force Control of Flapping Wings

    Science.gov (United States)

    2014-10-29

    diameter stainless steel wire. A high speed camera was used to record the smoke pattern at 1000 frame/s. 2.1 Aerodynamics of static/dynamic trailing...turbulent recirculation, Journal of Fluid Mechanics 683 (2011) 395- 416 . [27] H. Dong, R. Mittal, F.M. Najjar, Wake topology and hydrodynamic

  13. The Monopod Bucket Foundation

    DEFF Research Database (Denmark)

    Bakmar, Christian LeBlanc; Ahle, Kim; Nielsen, Søren A.

    2009-01-01

    Following the successful installation of a prototype of a monopod bucket foundation, also called a “monopod suction caisson”, at Horns Rev 2 Offshore Wind Farm, Denmark, in 2009, DONG Energy is currently developing a commercialization strategy. The monopod bucket foundation is a promising...

  14. Veneetsias võitis Hiina üllataja

    Index Scriptorium Estoniae

    2006-01-01

    Veneetsia filmifestivali parima filmi peaauhind Kuldlõvi läks Hiina režissööri Jia Zhang-Ke filmile "Vaikelu" ("Dong"). Hõbelõvi said Alain Resnais' "Isiklikud hirmud avalikes kohtades" ("Coeurs") ja Emanuele Crialese "Kuldne uks" ("Nuodomondo"). Parima näitleja Coppa Volpi said Helen Mirren ja Ben Affleck

  15. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Biosciences; Volume 31; Issue 5. Combinative effects of a bacterial type-III effector and a biocontrol bacterium on rice growth and disease resistance. Haiying Ren Ganyu Gu Juying Long Qian Yin Tingquan Wu Tao Song Shujian Zhang Zhiyi Chen Hansong Dong. Reviews Volume 31 Issue 5 ...

  16. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Chemical Sciences; Volume 122; Issue 6. Theoretical study of nucleophilic halogenalkylation of propylene oxide with halogenmethane and dihalogenmethane anion. Tao Liu Xiang-Chen Yin Guo-Dong Liu Zhang-Yu Yu. Full Papers Volume 122 Issue 6 November 2010 pp 901-909 ...

  17. A Real-Time Coastal Ocean Prediction Experiment for MREA04

    Science.gov (United States)

    2008-01-01

    coastal ocean prediction experiment for MREA04 Dong S. Ko *, Paul J. Martin, Clark D. Rowley, Ruth H. Preller Naval Research Laborator ,: S ’ntis Space...Jourml of Marine Svstem 69 t200S) 17 28 and various data streams for ocean bathymetry, clima - global ONFS or from a higher resolution regional ONFS

  18. Simulating coastal effects on an offshore wind farm

    DEFF Research Database (Denmark)

    van der Laan, Paul; Pena Diaz, Alfredo; Volker, Patrick

    the north-south oriented rows. This effect is visible in RANS, as plotted in Figure 1 and is also observed in SCADA data provided by DONG Energy. The wind resources at the wind farm and the power deficits, calculated by RANS, are compared with mesoscale simulations and SCADA data, respectively....

  19. Tako-tsubo cardiomyopathy after a quarrel.

    African Journals Online (AJOL)

    Tako-tsubo cardiomyopathy after a quarrel. Dong-Mei Jiang1,a, Ze-Wei Sunc2,a, Jie Han2. 1. Department of Cardiology, Biomedical research (therapy) center, Sir Run Run Shaw Hospital,. College of ... acterized by (1) sudden onset of chest pain or shortness of breath; (2) ... In the present report, we de- scribe a case of ...

  20. Where "Sign Language Studies" Has Led Us in Forty Years: Opening High School and University Education for Deaf People in Viet Nam through Sign Language Analysis, Teaching, and Interpretation

    Science.gov (United States)

    Woodward, James; Hoa, Nguyen Thi

    2012-01-01

    This paper discusses how the Nippon Foundation-funded project "Opening University Education to Deaf People in Viet Nam through Sign Language Analysis, Teaching, and Interpretation," also known as the Dong Nai Deaf Education Project, has been implemented through sign language studies from 2000 through 2012. This project has provided deaf…

  1. Aldehyde Dehydrogenase 1 and Raf Kinase Inhibitor Protein ...

    African Journals Online (AJOL)

    Xiang-Xiu Sun1, Qing-Shan Ma2, Tian-Feng Liu1, Ying Chen1, Yan Dong1 and. Lin-Lin Zhang1* ... cancer was developed and studied by histological examination. Immunohistochemical and .... (diaminobenzidine) Kit. Western blot analysis.

  2. Vicissitudes of Edo State Council for Arts and Culture Performing ...

    African Journals Online (AJOL)

    Abstract. The ding-dong charade of Edo State Council for Arts and Culture Performing Troupe (ESCFAACPT) cannot be divorced from the vacillating condition the establishment had been experiencing since its establishment. This condition is fore-grounded, first, on the cacophony of nomenclature that the council had been ...

  3. Chinese Herbal Medicines – Comparison of Doses Prescribed in ...

    African Journals Online (AJOL)

    Huan Dong Lu, Beijing 100029, China. *For correspondence: Email: fuyanlingbucm@126.com; Tel: (+86) 10-6428-6307; Fax: (+86) 10-6422-0858 ... pharmacopoeia, accounting for 57.14 % (32/56). The top three factors influencing dose ... herbal combination, property of Chinese herbs, quality of medicinal, have a strong ...

  4. JMBR VOLUME 14 Number 2.cdr

    African Journals Online (AJOL)

    FINEPRINT

    optometric practices in health insurance systems in Nigeria. By convenience, 40 ... 1 care seekers . It could be government run ... organizations and employment based. 7,. 8 .... practices are satisfied with out of pocket payments for ..... Sauerborn, R, & Dong, H. Performance evaluation of ... Family Income and the. Impact of a ...

  5. Hpa1 harpin needs nitroxyl terminus to promote vegetative growth ...

    Indian Academy of Sciences (India)

    2016-08-26

    Aug 26, 2016 ... Home; Journals; Journal of Biosciences; Volume 39; Issue 1. Hpa1 harpin needs nitroxyl terminus to ... Hansong Dong1 Chunling Zhang1. State Ministry of Education Key Laboratory of Integrated Management of Crop Pathogens and Insect Pests, Nanjing Agricultural University, Jiangsu, 210095, China ...

  6. Digitaria Effusa (Gramineae), a new species from Vietnam

    NARCIS (Netherlands)

    Veldkamp, J.F.

    1999-01-01

    During an agrostological survey in the Lam Dong Province, Vietnam, Mr. J.B. Hacker (St. Lucia, Queensland, Australia) collected a remarkable undescribed species of Digitaria. Among the Asian taxa it is peculiar because of its montane provenance coupled with a combination of an inflorescence with

  7. Estimating Energy Efficiency of Connected and Autonomous Vehicles in a Mixed Fleet

    Science.gov (United States)

    2018-05-01

    Jing Dong (orcid.org/0000-0002-7304-8430); Liang Hu (orcid.org/0000-0001-6351-8542); Chaoru Lu (orcid.org/0000-0001-8418-7658); Connected and autonomous vehicle (CAV) technologies are likely to be gradually implemented over time and in a traffic envi...

  8. Fertigation with domestic wastewater: Uses and implications

    African Journals Online (AJOL)

    Jose Geraldo

    2016-05-18

    Graduação da Rede Bionorte- .... are pollution of surface and groundwater, salinization, soil .... serious problems in ponds, rivers and seas (Wang and ..... Rio de. Janeiro: ABES: 1. Kong Z, Li L, Feng C, Chen N, Dong S, Hub W (2015).

  9. Journal of Chemical Sciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Design, synthesis and cytotoxicity of novel N-benzylpiperidin-4-one oximes on human cervical cancer cells. Someshwar D Dindulkar Ira Bhatnagar Rupesh L Gawade Vedavati G Puranik Se-Kwon Kim Dong Hyun Anh Paramasivam Parthiban Yeon Tae Jeong. Regular Articles Volume 126 Issue 3 May 2014 pp 861-873 ...

  10. Bulletin of Materials Science | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Xiuqiang Li1 Dong Zhang1 Peiying Zhu1 Chao Yang1. Key Laboratory of Advanced Civil Engineering Materials, Ministry of Education, College of Materials Science and Engineering, Tongji University, 4800 CaoAn Road, Shanghai 200092, China ...

  11. Udvikling af LED lyskilder og lamper. Slutrapport for PSO 337-068

    DEFF Research Database (Denmark)

    Dam-Hansen, Carsten; Petersen, Paul Michael; Thestrup Nielsen, Birgitte

    This report is the final and concluding report on the research and development project “Development of LED light sources and lamps” PSO no. 337-068 supported by Dansk Energi – Net. The project was a collaboration between Risø National laboratory, Louis Poulsen Lighting, Dong Energy, Laboratoriet...

  12. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Author Affiliations. Ruoxue Liu1 Beibei Lü1 Xiaomeng Wang1 Chunling Zhang1 Shuping Zhang1 Jun Qian1 Lei Chen1 Haojie Shi1 Hansong Dong1. State Ministry of Agriculture Key Laboratory of Monitoring and Management of Crop Pathogens and Insect Pests, Nanjing Agricultural University, Nanjing 210095, China ...

  13. Short communication Validation of the 50k Illumina goat SNP chip in ...

    African Journals Online (AJOL)

    Simon

    2015-03-12

    Mar 12, 2015 ... Genet. App. Livest. Prod. Vancouver, BC, Canada, 2014. Poster presentation, 882. Davis, N.A., Pandey, A. & McKinney, B.A., 2011. Real-world comparison of CPU and GPU implementations of SNPrank: a network analysis tool for GWAS. Bioinformatics 27, 284-285. Dong, Y., Xie, M., Jiang, Y., Xiao, N., Du, ...

  14. Cloning and mRNA expression pattern analysis under low ...

    African Journals Online (AJOL)

    This research cloned endochitinase-antifreeze protein precursor (EAPP) gene of Dong-mu 70 rye (Secale cereale) by designing special primers according to Genbank's EAPP gene sequence, and analyzing the influence of low temperature stress on the expression of mRNA with RT-PCR. The results indicated that the ...

  15. High frequency plant regeneration from mature seed- derived callus ...

    African Journals Online (AJOL)

    PRECIOUS

    2009-12-15

    Dec 15, 2009 ... Ki-Won Lee, Gi Jun Choi, Ki-Yong Kim, Hee Chung Ji, Hyung Soo Park, Sei Hyung Yoon and ... Gramineae family plants (Ha et al., 2001; Dong and Qu, ..... Lee SH, Ahsan N, Lee KW, Kim DH, Lee DG, Kwak SS, Kwon SY, ...

  16. Nutrient Distributions, Transports, and Budgets on the Inner Margin of a River-Dominated Continental Shelf

    Science.gov (United States)

    2013-10-02

    Nutrient distributions, transports, and budgets on the inner margin of a river-dominated continental shelf John C. Lehrter,1 Dong S. Ko,2 Michael C...and D. C. Biggs (1993), The influence of advec- tion on the spatial variability of nutrient concentrations on the Texas- Louisiana continental shelf

  17. Kuldlõvi võitis üllatusena Hiina film tammi ehitamisest / A. L.

    Index Scriptorium Estoniae

    A. L.

    2006-01-01

    Veneetsia filmifestivali parima filmi peaauhind Kuldlõvi läks Hiina režissööri Jia Zhang-Ke filmile "Vaikelu" ("Dong"). Parima näitleja Coppa Volpi said Helen Mirren ja Ben Affleck, elutööauhinna sai režissöör David Lynch

  18. International Journal of Engineering, Science and Technology - Vol ...

    African Journals Online (AJOL)

    electrolysis pretreatment · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Shuchuan Peng, Lili Zhao, Xixi Liu, Dong Chen. http://dx.doi.org/10.4314/ijest.v2i7.63748 ...

  19. Load Coefficients on Grates used for Wind Turbine Access Platforms

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Rasmussen, Michael R.; Frigaard, Peter

    In this report is presented the results of tests carried out at Dept. of Civil Engineering, Aalborg University (AAU) on behalf of DONG Energy A/S and Vattenfall A/S, Denmark. The objective of the tests was to investigate the load coefficient on different platform grates and a solid plate for desi...

  20. Download this PDF file

    African Journals Online (AJOL)

    Dan Jiang 1*, Jian-Hong Zhou 2*, Jue Zhou 3 , Ying-Er Gu 2, Dong-Xia Yang 4, Qing .... Women were informed about the short- and long-term benefits of HRT. .... Current employment status .... randomized, double-blind, controlled trial of a Chinese herbal formula (Er-Xian decoction) for menopausal symptoms in Hong Kong.

  1. YUAN-BO SUN

    Indian Academy of Sciences (India)

    Home; Journals; Journal of Genetics. YUAN-BO SUN. Articles written in Journal of Genetics. Volume 97 Issue 1 March 2018 pp 173-178 RESEARCH ARTICLE. Investigating multiple dysregulated pathways in rheumatoid arthritis based on pathway interaction network · XIAN-DONG SONG XIAN-XU SONG GUI-BO LIU ...

  2. Magnetic Resonance Imaging of Heart Failure Using a Swine Model

    Science.gov (United States)

    2011-03-21

    Suppl):I437-442. 36. McAlister FA, Teo KK, Taher M, Montague TJ, Humen D, Cheung L, Kiaii M, Yim R, Armstrong PW. Insights into the contemporary...Imaging 2001;13:714-721. 8. Ho VB, Meaney JF, Kent KC , Choyke PL, Watts R, Hood MN, Wang Y, Winchester P, Dong Q, Prince MR. Bolus-chase peripheral MR

  3. Epidermal Growth Factor Receptor Transactivation by the Cannabinoid Receptor (CB1) and Transient Receptor Potential Vanilloid 1 (TRPV1) Induces Differential Responses in Corneal Epithelial Cells

    Science.gov (United States)

    2010-01-01

    inflammatory cytokine release in corneal epithelium through MAPK signaling. J. Cell Physiol. 213, 730e739. Zhang, J., Li , H., Wang, J., Dong, Z., Mian ...Kang, S.S., Li , T., Xu, D., Reinach, P.S., Lu, L., 2000. Inhibitory effect of PGE2 on EGF- induced MAP kinase activity and rabbit corneal epithelial

  4. Whole-genome sequence of Clostridium lituseburense L74, isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus.

    Science.gov (United States)

    Lee, Yookyung; Lim, Sooyeon; Rhee, Moon-Soo; Chang, Dong-Ho; Kim, Byoung-Chan

    2016-03-01

    Clostridium lituseburense L74 was isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus collected in Yeong-dong, Chuncheongbuk-do, South Korea and subjected to whole genome sequencing on HiSeq platform and annotated on RAST. The nucleotide sequence of this genome was deposited into DDBJ/EMBL/GenBank under the accession NZ_LITJ00000000.

  5. to view fulltext PDF

    Indian Academy of Sciences (India)

    2013-02-09

    Feb 9, 2013 ... potential invading pathogens and mount successful defences ...... methyl-SA strongly suggest that SA is not the mobile signal. (Vernooij et al. 1994 ...... Wang WH, Yi XQ, Han AD, Liu TW, Chen J, Wu FH, Dong XJ,. He JX, Pei ...

  6. Interactions between traditional Chinese medicine and western drugs in Taiwan: A population-based study.

    Science.gov (United States)

    Chen, Kuan Chen; Lu, Richard; Iqbal, Usman; Hsu, Ko-Ching; Chen, Bi-Li; Nguyen, Phung-Anh; Yang, Hsuan-Chia; Huang, Chih-Wei; Li, Yu-Chuan Jack; Jian, Wen-Shan; Tsai, Shin-Han

    2015-12-01

    Drug-drug interactions have long been an active research area in clinical medicine. In Taiwan, however, the widespread use of traditional Chinese medicines (TCM) presents additional complexity to the topic. Therefore, it is important to see the interaction between traditional Chinese and western medicine. (1) To create a comprehensive database of multi-herb/western drug interactions indexed according to the ways in which physicians actually practice and (2) to measure this database's impact on the detection of adverse effects between traditional Chinese medicine compounds and western medicines. First, a multi-herb/western medicine drug interactions database was created by separating each TCM compound into its constituent herbs. Each individual herb was then checked against an existing single-herb/western drug interactions database. The data source comes from the National Health Insurance research database, which spans the years 1998-2011. This study estimated the interaction prevalence rate and further separated the rates according to patient characteristics, distribution by county, and hospital accreditation levels. Finally, this new database was integrated into a computer order entry module of the electronic medical records system of a regional teaching hospital. The effects it had were measured for two months. The most commonly interacting Chinese herbs were Ephedrae Herba and Angelicae Sinensis Radix/Angelicae Dahuricae Radix. Ephedrae Herba contains active ingredients similar to in ephedrine. 15 kinds of traditional Chinese medicine compounds contain Ephedrae Herba. Angelicae Sinensis Radix and Angelicae Dahuricae Radix contain ingredients similar to coumarin, a blood thinner. 9 kinds of traditional Chinese medicine compounds contained Angelicae Sinensis Radix/Angelicae Dahuricae Radix. In the period from 1998 to 2011, the prevalence of herb-drug interactions related to Ephedrae Herba was 0.18%. The most commonly prescribed traditional Chinese compounds were

  7. Fra uncini e uncinate. Riflessioni sulla parodia nel Cinquecento

    Directory of Open Access Journals (Sweden)

    Nicola Catelli

    2010-06-01

    Full Text Available L’articolo prende in considerazione una sequenza del poemetto pornografico La Puttana errante di Lorenzo Venier (1530 ca. che presenta una versione parodica dell’episodio di Angelica e dell’eremita narrato nell’Orlando furioso. Dopo un puntuale raffronto fra i due testi, l’analisi giunge a constatare come tale parodia venga utilizzata non tanto in termini di contestazione o correzione di un modello illustre, quanto come proposta critica di un rapporto con le fonti letterarie stratificato e ironicamente distaccato.This article analyses a sequence of Lorenzo Venier’s pornographic poem La Puttana errante (about 1530 that offers a parodic version of the episode of Angelica and the hermit in Orlando furioso. After a comparison between the texts, the article suggests that Venier’s parody is not a contestation or correction of the illustrious model, but a proposal of a stratified, detached and ironic relation with the sources.

  8. Visões do transe religioso

    Directory of Open Access Journals (Sweden)

    Nilse Davanço Rizzi

    1997-06-01

    Full Text Available O ponto de partida é o fenômeno do transe considerado num contexto ritual religioso, procurando, num primeiro momento, conceituar os diferentes tipos de transe, relacionando-os às religiões nas quais aparece. Num segundo momento, a preocupação é desvendar como o transe é visto pelas pessoas e quais opiniões elas tem a respeito. Neste sentido, buscamos resgatar a partir de quais religiões o transe está mais frequentemente associado, quais manifestações estão identificadas a ele e como as pessoas veem tais manifestações

  9. Immunomodulatory and Antidiabetic Effects of a New Herbal Preparation (HemoHIM) on Streptozotocin-Induced Diabetic Mice

    OpenAIRE

    Kim, Jong-Jin; Choi, Jina; Lee, Mi-Kyung; Kang, Kyung-Yun; Paik, Man-Jeong; Jo, Sung-Kee; Jung, Uhee; Park, Hae-Ran; Yee, Sung-Tae

    2014-01-01

    HemoHIM (a new herbal preparation of three edible herbs: Angelica gigas Nakai, Cnidium officinale Makino, and Paeonia japonica Miyabe) was developed to protect immune, hematopoietic, and self-renewal tissues against radiation. This study determined whether or not HemoHIM could alter hyperglycemia and the immune response in diabetic mice. Both nondiabetic and diabetic mice were orally administered HemoHIM (100 mg/kg) once a day for 4 weeks. Diabetes was induced by single injection of streptozo...

  10. [Research on compatibility of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung based on complex network analysis].

    Science.gov (United States)

    Li, Meng-Wen; Fan, Xin-Sheng; Zhang, Ling-Shan; Wang, Cong-Jun

    2017-09-01

    The applications of prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung in contemporary literatures from 1949 to 2016 are compiled and the data mining techniques containing scale-free complex network method are utilized to explore its practical characteristics, with comparison between modern and ancient ones. The results indicate that malignant neoplasms, coronary heart disease which present Qi deficiency and blood stasis type are the main diseases treated by prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung according to the reports during 1949 to 2016. The complex network connection shows that Glycyrrhizae Radixet Rhizoma, Angelicae Sinensis Radix, Astragali Radix, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma are the primary drugs related to Ginseng Radix et Rhizoma and Trogopterus Dung. The next are Paeoniae Radix Alba, Atractylodis Macrocephalae Rhizoma, Persicae Semen, Foria, et al. Carthami Flos, Notoginseng Radix et Rhizoma, Cyperi Rhizoma, Bupleuri Radix are the peripheral ones. Also, Ginseng Radix et Rhizoma-Glycyrrhizae Radixet Rhizoma, Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Angelicae Sinensis Radix, Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Astragali Radix, Trogopterus Dung-Astragali Radix are the main paired drugs. The paired drugs including Ginseng Radix et Rhizoma-Trogopterus Dung-Glycyrrhizae Radixet Rhizoma, Ginseng Radix et Rhizoma-Trogopterus Dung-Angelicae Sinensis Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Astragali Radix, Ginseng Radix et Rhizoma-Trogopterus Dung-Typhae Pollen have a higher support degree. The main compatible drugs are different in ancient and modern prescriptions including Ginseng Radix et Rhizoma and Trogopterus Dung. Notoginseng Radix et Rhizoma, Typhae Pollen, Salviae Miltiorrhizae Radix et Rhizoma, Astragali Radix are utilized frequently in modern prescriptions while less used in ancient ones. It is also shown

  11. Tarptautinė konferencija "Biblioteka: informacija ir žinios kiekvienam" / Viktorija Pukėnaitė, Žydrė Vėtienė

    Index Scriptorium Estoniae

    Pukėnaitė, Viktorija

    2015-01-01

    Eesti Raamatukoguhoidjate Ühingu esindus osales 27.-28. aprillini Vilniuse parlamendis toimunud rahvusvahelisel konverentsil „Raamatukogu: teave ja teadmised kõigile“. Juuresolevatel fotodel Eesti Raamatukoguhoidjate Ühingu juhatuse esinaine Katre Riisalu ja Viljandi Linnaraamatukogu töötaja Veronika Raudsepp Linnupuu. Nr. 6 juttu Tallinna Keskraamatukogu esindaja Angelica Õunapuu ja Tartu Ülikooli esindaja Mai Põldaasa ettekannetest

  12. Analytical Research to Determine the effects of the Components of ONGABO on the Viability of HepG2 Cancer Cells by Using the Sovereign, Minister, Assistant and Courier Principle ().

    Science.gov (United States)

    Shin, Jeong-Hun; Jun, Seung-Lyul; Hwang, Sung-Yeoun; Ahn, Seong-Hun

    2012-12-01

    This study used the basic principle of Oriental medicine, the sovereign, minister, assistant and courier principle () to investigate the effects of the component of ONGABO, which is composed of Ginseng Radix (Red Ginseng), Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen and Curcumae tuber on the viability of HepG2 cells. Single and mixed extracts of the component of ONGABO were prepared by lypohilizing powder of Red Ginseng (6-year root from Kanghwa), Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen, Curcumae Tuber (from Omniherb Co., Ltd., Korea) at the laboratory of herbal medicine in Woosuk University and were eluted after being macerated with 100% ethanol for three days. The cell viability of HepG2 was determined by using an absorptiometric analysis with PrestoBlue (Invitrogen) reagent after the plate had been incubated for 48 hours. All of the experiments were repeated three times to obtain the average value and standard deviation. The statistical analysis was done and the correlation factor was obtained by using Microsoft Office Excel 2007 and Origin 6.0 software. Although Ginseng Radix (Red Ginseng) and Schisandrae Fructus did not enhance the viability of HepG2 cells, they were shown to provide protection of those cells. On the other hand, Angelica Gigantis Radix decreased the viability of HepG2 cells significantly, Cuscuta Semen and Curcumae Tuber had a small or no effect on the viability of HepG2 cells. In the sovereign, minister, assistant and courier principle (), Ginseng Radix (Red Ginseng) corresponds to the sovereign component because it provides cell protection effects, Angelica Gigantis Radix corresponds to minister medicinal because it kills cells, Schisandrae Fructus corresponds to the assistant medicinal to help red ginseng having cell protect effects. Cuscuta Semen and Curcumae Tuber correspond to the courier medicinal having no effect in cell viability in HepG2. We hope this study provides motivation for advanced research

  13. Translations on Latin America, Number 1568.

    Science.gov (United States)

    1976-11-10

    the states and municipalities , [passage indistinct] The balance of payments will have a deficit this year of 44 billion cruzeiros, 17 percent more...to see the regime experiment with the first municipal elec- tions with universal suffrage in one province, Matanzas Province. It is true that the...the House of Chile, signed by Hugo Vigorena, from Angelica Arenal de Siquieros, from the dissident group of the PPS, Alejandro Gascon Mercado , Manuel

  14. 当归补血汤及其拆方影响肝脏血管新生的药效特点及作用机制

    Directory of Open Access Journals (Sweden)

    GUO Tao

    2014-04-01

    Full Text Available ObjectiveTo observe the pharmacodynamic characteristics of Danggui Buxue decoction (containing Angelica sinensis and its separated recipes in treating liver fibrosis and angiogenesis. MethodsForty-eight Wistar rats were randomly divided into 6 groups: normal group, model group, Danggui Buxue decoction group, Astragalus membranaceus group, Angelica sinensis group, and sorafenib control group. In all groups except normal group, a rat model of liver fibrosis was established using carbon tetrachloride combined with high-fat and low-protein diet. Liver tissue inflammation was observed by HE staining, while collagen deposition by Sirius red staining. Serum levels of alanine aminotransferase (ALT, aspartate aminotransferase (AST, and albumin (Alb and the malondialdehyde (MDA content, superoxide dismutase (SOD activity, nitric oxide (NO content, and nitricoxide synthase (NOS activity in liver tissue were determined by a test kit. The hydroxyproline (Hyp content in liver tissue was determined by hydrochloric acid hydrolysis. Sinusoidal endothelial fenestrae were observed by scanning electron microscope, and liver capillaries by synchrotron radiation X-ray two-dimensional imaging. Comparisons between groups were made by one-way analysis of variance; the least significant difference test was used when variances were equal, and the Tamhane′s T2 test was used when variances were unequal. ResultsThe Danggui Buxue decoction group, Astragalus membranaceus group, and Angelica sinensis group had significantly increased serum Alb levels (P<0.05 and significantly decreased serum AST levels (P<0.05; the Danggui Buxue decoction group and Astragalus membranaceus group had significantly decreased serum ALT levels (P<005. All treatment groups had significantly decreased liver hydroxyproline content (P<0.05. In the liver tissues of all treatment groups, the vascular texture was reduced, and the number of sinusoidal endothelial fenestrae was increased . The

  15. Nanobiomaterials development and applications

    CERN Document Server

    Papaefthymiou-Davis, Georgia C

    2013-01-01

    Nanomaterials in Nanobiotechnologies: Preparation, Characterization, and ApplicationsBio-Inspired Magnetic NanoparticlesGeorgia C. Papaefthymiou and Eamonn DevlinNanoparticles for BioimagingHye Sun Park and Yong Taik LimBiomedical Applications of Dendrimer Porphyrin or PhthalocyanineWoo-Dong Jang and Won-Gun KohPolymeric Nanoparticles in Cancer TherapyHeebeom Koo, Ji Young Yhee, Ick Chan Kwon, Kwangmeyung Kim, and Ramesh SubbiahCarbon Nanotube BioconjugatesMonica Samal, Dong Kee Yi, and Shashadhar SamalBiocatalytic NanosystemsJaehong Lim and Su Seong LeeMagnetically Induced Hyperthermia for Biomedical ApplicationsMichael Fardis, Ioannis Rabias, Georgios Diamantopoulos, Eleni Karakosta, Danai Tsitrouli, Vassilios Tzitzios, and Georgios PapavassiliouSoft Block Nanobuilding: New Preparation Routes of Soft Nanomaterials Using BiomoleculesEngineered Biomolecules as NanomaterialsYun Jung Lee and Ki Tae NamNanomaterials and Bio-MEMS: Nano- and Microscale Hybridization of Materials and ApplicationsMicrofluidic-Based ...

  16. A Study of Strategic Lessons Learned in Vietnam. Volume 2. South Vietnam

    Science.gov (United States)

    1979-12-01

    transportation in the Delta regions. They cleared and cultivated " virgin lands" for rice fields and plantations and established local market villages...combination of cleverness and ruth- lessness the Lao Dong Party was able to divide, discredit or eliminate all potential nationalistic competitors . The...all-important Tet holiday , and that they had brought heavy fighting into the heart of the cities - previously relatively secure sanctuaries. The brutal

  17. A Study of Strategic Lessons Learned in Vietnam. Volume 8. Results of the War

    Science.gov (United States)

    1980-05-09

    BDNI CORPORATION Political Bureau Membeirs (Fourth Party Congress ranking order) Le Duan fruong Chinh Phamn Van Dong Phamn Huna Le Duc Tho Vo Nguyen...the Laotian monarchy was abolished and the Democratic People’s Republic of Laos established. In a political trans - formation which passed with little...Strategic Studies, thus observed, " in the particular case of Vietnam, the general effect was to inaugurate a tran - sitional phase of Americao policy which

  18. The backwaters of glory and hardship

    International Nuclear Information System (INIS)

    Kim, Dong Hun

    2001-07-01

    This book starts the background of this writing, the letter to his father, a brief summary of his career. It is Dr. Kim Dong Hun's an autobiographical report about introduction into nuclear power, building TRIGA Mark-III and propel the business of research reactor, establishing nuclear safe center, beginning and president Lee, Seung Man, passion over TRIGA. It deals with carrying out building the HANARO about background, the process of the business.

  19. Oligosaccharide nanomedicine of alginate sodium improves therapeutic results of posterior lumbar interbody fusion with cages for degenerative lumbar disease in osteoporosis patients by downregulating serum miR-155

    OpenAIRE

    Qu Y; Wang Z; Zhou H; Kang M; Dong R; Zhao J

    2017-01-01

    Yang Qu, Zhengming Wang, Haohan Zhou, Mingyang Kang, Rongpeng Dong, Jianwu Zhao Department of Orthopedics, The Second Hospital of Jilin University, Changchun, People’s Republic of China Abstract: Degenerative lumbar disease (DLD) is a significant issue for public health. Posterior lumbar intervertebral fusion with cages (PLIFC) has high-level fusion rate and realignment on DLD. However, there are some complications following the surgery. Alginate oligosaccharides (AOS) have antiox...

  20. Biologically Assembled Quantum Electronic Arrays

    Science.gov (United States)

    2013-06-07

    Koh , Faxian Xiu, Xingchen Ye, Dong-Kyun Ko, Kang L. Wang, Cherie R. Kagan, Christopher B. Murray. Multiscale Periodic Assembly of Striped Nanocrystal...study is the LlM method (See M. T. Raman et al, Applied . Physics L etters 94, 042507, 2009). This method is a type of first-order reversal...Demonstrated graphene field- effect transistor: (top) optical Image of transferred graphene, (middle) Raman spectrum, (bottom) current voltage

  1. Gauge covariant fermion-photon vertex in quenched, massless three dimensional quantum electrodynamics

    International Nuclear Information System (INIS)

    Tjiang, P.C.; Burden, C.J.

    1998-01-01

    Full text: We consider the problem of designing an Ansatz for the transverse part of the fermion-photon vertex in QED 3 . Our work is based on that of Ball and Chiu, who consider restrictions placed on the vertex by the U(1) Ward identity, and on subsequent modifications which attempt to satisfy the Landau-Khalatnikov transformation rules. A class of vertex Ansaetze including that proposed by Dong et al is tested using the gauge invariance of the vacuum polarisation scalar

  2. Immunomodulatory Role of Diet and Adipokines in Multiple Sclerosis and Its Animal Model

    Science.gov (United States)

    2015-09-01

    signaling pathways that are starting to be elucidated ( Mao , Kikani et al. 2006, Holland, Miller et al. 2011). AdipoR1 and R2 are expressed on various cell...been reported downstream of AdipoRs ( Mao , Kikani et al. 2006). Recently, it has been shown that adiponectin potently stimulates ceramidase activity...collaborator Prof. Lily Dong detailed protocols to produce recombinant full-length and globular adiponectin. We have encountered some technical issues in

  3. The Role of SIRT1 In Breast Cancer Stem Cells

    Science.gov (United States)

    2016-09-01

    2009;9:123-8. 56. Ma W, Xiao GG, Mao J, Lu Y, Song B, Wang L, Fan S, Fan P, Hou Z, Li J, Yu X, 20 Wang B, Wang H, Wang H, Xu F, Li Y, Liu Q, Li L...Int J Biol Sci. 2010;6:599-612. 63. Zhang Y, Zhang M, Dong H, Yong S, Li X, Olashaw N, Kruk PA, Cheng JQ, Bai W, Chen J, Nicosia SV, Zhang X

  4. Contribution of Interstitial Deletion of 21q22.2-3 per se to Prostate Cancer Progression in Tumors Harboring TMPRSS2-ERG Translocations

    Science.gov (United States)

    2015-12-01

    harboring TMPRSS2- ERG translocations PRINCIPAL INVESTIGATOR: Yan Dong CONTRACTING ORGANIZATION: Tulane University New Orleans, LA 70112...0485 to prostate cancer progression in tumors harboring TMPRSS2- ERG translocations 5b. GRANT NUMBER W81XWH-14-1-0485 5c. PROGRAM ELEMENT NUMBER...Unlimited 13. SUPPLEMENTARY NOTES 14. ABSTRACT TMPRSS2- ERG gene fusions are present in close to 50% of human prostate cancers. Approximately half of the

  5. Validation of a high-performance liquid chromatography/fluorescence detection method for the simultaneous quantification of fifteen polycyclic aromatic hydrocarbons

    DEFF Research Database (Denmark)

    Hansen, Åse Marie; Olsen, I L; Holst, E

    1991-01-01

    A high-performance liquid chromatography/fluorescence method using multiple wavelength shift for simultaneous quantification of different PAH compounds was developed. The new method was superior to the methods of DONG and GREENBERG [J. Liquid Chromatogr. 11, 1887-1905 (1988)] and WISE et al...... that no systematic errors, and only small unsystematic errors, could be demonstrated. Furthermore, the method had a good reproducibility and a high sensitivity....

  6. A Clinician-Centered Evaluation of the Usability of AHLTA and Automated Clinical Practice Guidelines at TAMC

    Science.gov (United States)

    2009-10-01

    gathering has been rescheduled to November 14, 2009, in San Francisco, at the AMIA Conference location. August 14, 2009, SOADEX provided a draft system...Bethesda. MD, USA d Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Austria • Department of Nursing . lnha University...scheduled. Insook Cho, PhD, RN Associate Professor, Maternity Nursing & Nursing Informat- ics, lnha University, Younghyun-dong, Nam-gu, Jncheon, South

  7. Nanoscale Magnetism in Next Generation Magnetic Nanoparticles

    Science.gov (United States)

    2018-03-17

    reaction catalyzed by glucose oxidase as shown in the following chemical equations:13-14 glucose + glucose oxidase(ox) → gluconic acid + glucose...Hanyang University (HYU) - Mailing Address : Room 404, Dept. of Material Science & Engineering , Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul... chemical and biological detection and conformal and flexible interfaces with biological systems. DISTRIBUTION A. Approved for public release

  8. A Novel Therapeutic Modality for Advanced Stage Prostate Cancer Treatment

    Science.gov (United States)

    2017-10-01

    Androgen Receptor Signaling Inhibitors Repress Prostate Cancer Growth by Downregulating Androgen Receptor Splice Variants, EZH2, and Src. Cancer ...research 2015;75(24):5309-17. 18. Wadosky KM, Koochekpour S. Androgen receptor splice variants and prostate cancer : From bench to bedside. Oncotarget...2017;8(11):18550-76. 19. Cao S, Zhan Y, Dong Y. Emerging data on androgen receptor splice variants in prostate cancer . Endocrine-related cancer

  9. The Elusive China-Japan-South Korea Free Trade Agreement

    Science.gov (United States)

    2015-09-01

    Keohane and Joseph S. Nye, Power & Interdependence, 4th edition (Boston: Pearson , 2011), 232–3. 8 Dong Wang, “China-Japan Relations - Now What?,” PacNet...trilateral FTA could provide Japan and South Korea with a sense of assurance regarding Chinese foreign policy, which is often seen as aggressive...successfully led the charge against JA-Zenchu and removed its authority to audit and guide all Japanese farming cooperatives, removing a coercive tool to

  10. Katrin Denev pokazala harakter

    Index Scriptorium Estoniae

    2006-01-01

    Veneetsia 63. filmifestivali auhinnatutest, kellest vaid Stephen Frears'i filmis "Kuninganna" ("The Queen") peaosa kehastanud Helen Mirren oli üks favoriitidest. Parima filmi peaauhind Kuldlõvi läks üllatuslikult Hiina režissööri Jia Zhang-Ke filmile "Vaikelu" ("Dong"). Ka teistest Veneetsia 63. filmifestivali võitjatest. Festivali žüriid juhatas Catherine Deneuve

  11. EGFR-Dependent Regulation of Matrix-Independent Epithelial Cell Survival. Addendum

    Science.gov (United States)

    2007-04-01

    of the original proposal. The results obtained have identified key players that coordinate keratinocyte survival dependent on soluble growth factors...2004;6:203–8. 4. Duffey DC, Chen Z, Dong G, et al. Expression of a dominant-negative mutant inhibitor- nBa of nuclear fac- tor-nB in human head and neck...Attempts to treat such tumors with EGFR antagonists have met with remarkable initial successes , particularly when EGFR antagonists were used in

  12. Miao Finery

    Institute of Scientific and Technical Information of China (English)

    1999-01-01

    DURING a business trip toTaijiang County in GuizhouProvince’s Miao and DongAutonomous Prefecture, I caught upwith the Jingqiao Festival on the secondday of the second lunar month. Peoplefrom neighboring villages many milesaway came to participate in this grandgathering, carrying baskets on theirshoulders with their best holiday dresses,silver ornaments, wine and food as wellas lusheng, their favorite musicalinstrument.

  13. Course NICER in gastrointestinal and urogenital radiology

    International Nuclear Information System (INIS)

    Aksel Kruse; Nolan, D.J.; Allison, D.J.; Jackson, J.; Gibson, R.

    1998-01-01

    Course of NICER (Nycomed Intercontinental Continuing Education in Radiology) in gastrointestinal and urogenital radiology in the frameworks of NICER program. This program is one of the best educational programs the purpose of which consists in education of maximum good quality, free of marketing and advertisement accessible to roentgenologists of all the countries. The above course was presented in Hua Dong Hospital, Shanghai, China, April 18-21, 1996

  14. Paraganglioma of the vagina: a case report and review of the literature

    OpenAIRE

    Cai, Tao; Huang,Yu; Li,Yucong; Jiang,Qingming; Wang,Dong

    2014-01-01

    Tao Cai,1 Yucong Li,2 Qingming Jiang,3 Dong Wang,2 Yu Huang2 1Department of Dermatology, The First Affiliated Hospital of Chongqing Medical University, 2Department of Gynecologic Oncology, 3Department of Pathology, Chongqing Cancer Research Institute, Chongqing, People’s Republic of China Abstract: Vaginal paraganglioma is a rare and unusual tumor occurring in the vaginal wall. It is a solitary primary paraganglioma, especially in atypical sites. Herein, we report an unusual case o...

  15. Leading Players of the Global Renewable Energy Equipment Industry. Overview of Groups - SWOTs - Benchmarking - Company Profiles and Financials

    International Nuclear Information System (INIS)

    2017-06-01

    This study presents: The medium-term and mega trends of the industry market developments and geographical segments; The competitive landscape and the main corporate rankings; The main conclusions of the report, summarised in 10 analytical slides. Content: 1. Overview: The Sector, Ranking, Performance Analysis; 2. Company Profiles: Toshiba, Vestas, Dong Energy, GE Renewable Energy, Siemens, Goldwind, First Solar, SunPower, Andritz, Yingli Green Energy; 3. Sources; 4. Annexes

  16. Control of Cellular Structural Networks Through Unstructured Protein Domains

    Science.gov (United States)

    2016-07-01

    0195-z Albert J. Keung, Meimei Dong, David V. Schaffer, Sanjay Kumar. Pan-neuronal maturation but not neuronal subtype differentiation of adult neural...thin film of silicon dioxide deposited on a reflective silicon wafer. The intensity of the fluorescence excitation light is axially modulated by...star rating in Faculty of 1000. C. ENGINEERING NEURONAL BEHAVIOR VIA CYTOSKELETAL NETWORKS We have sought to understand how adult neural stem cells

  17. Digitaria Effusa (Gramineae), a new species from Vietnam

    OpenAIRE

    Veldkamp, J.F.

    1999-01-01

    During an agrostological survey in the Lam Dong Province, Vietnam, Mr. J.B. Hacker (St. Lucia, Queensland, Australia) collected a remarkable undescribed species of Digitaria. Among the Asian taxa it is peculiar because of its montane provenance coupled with a combination of an inflorescence with well-developed common axis with alternate racemes, the presence of a small lower glume, and the absence of any indument on the spikelet. Somewhat similar is D. wallichiana (Steud.) Stapf, also a monta...

  18. Vietnamese Victims of Agent Orange and U.S.-Vietnam Relations

    Science.gov (United States)

    2009-05-28

    samples—usually blood, breast milk , or adipose tissue55—from people who may have been 48...have been exposed to Agent Orange.56 Average blood levels of TEQ were nearly six times higher among the people from sprayed areas, average breast milk ...company founded in the United States, but now also operating in China and Vietnam. RAAS has donated over 17 billion dong ($1 million) to the VRC, and

  19. A study on gamma dose rate in Seoul (I)

    International Nuclear Information System (INIS)

    Kim, You Hyun; Kim, Chang Kyun; Choi, Jong Hak; Kim, Jeong Min

    2001-01-01

    This study was conducted to find out gamma dose rate in Seoul, from January to December in 2000, and the following results were achieved : The annual gamma dose rate in Seoul was 17.24 μR/hr as average. The annual gamma dose rate in subway of Seoul was 14.96 μR/hr as average. The highest annual gamma dose rate was Dong-daemon ku. Annual gamma dose rate in Seoul was higher autumn than winter

  20. Department of Defense HIV/AIDS Prevention Program (DHAPP), 2012

    Science.gov (United States)

    2013-06-04

    of the GDP. Vietnam’s managed currency , the dong, has been devalued by 20% since 2008, but its value remained stable in 2012. Foreign direct...WEST REGION Benin 90 Burkina Faso 92 Côte d’Ivoire 94 Gambia, The 97 Ghana 99 Guinea 102 Liberia 104 Mali 107 Niger 109 Nigeria 111 Senegal...Infectious Diseases Institute (on the campus of Makerere University, Kampala, Uganda) IMF - International Monetary Fund IMilHAC – International

  1. The baseline characteristics and interim analyses of the high-risk sentinel cohort of the Vietnam Initiative on Zoonotic InfectiONS (VIZIONS)

    OpenAIRE

    Carrique-Mas, Juan J.; Tue, Ngo T.; Bryant, Juliet E.; Saylors, Karen; Cuong, Nguyen V.; Hoa, Ngo T.; An, Nguyen N.; Hien, Vo B.; Lao, Pham V.; Tu, Nguyen C.; Chuyen, Nguyen K.; Chuc, Nguyen T.K.; Tan, Dinh V.; Duong, Hoang Van V.; Toan, Tran K.

    2015-01-01

    The Vietnam Initiative for Zoonotic Infections (VIZIONS) includes community-based 'high-risk sentinel cohort' (HRSC) studies investigating individuals at risk of zoonotic infection due to occupational or residential exposure to animals. A total of 852 HRSC members were recruited between March 2013 and August 2014 from three provinces (Ha Noi, Dak Lak, and Dong Thap). The most numerous group (72.8%) corresponded to individuals living on farms, followed by slaughterers (16.3%) and animal health...

  2. Application of PCR-DGGE method for identification of nematode communities in pepper growing soil

    OpenAIRE

    Nguyen, Thi Phuong; Ha, Duy Ngo; Nguyen, Huu Hung; Duong, Duc Hieu

    2017-01-01

    Soil nematodes play an important role in indication for assessing soil environments and ecosystems. Previous studies of nematode community analyses based on molecular identification have shown to be useful for assessing soil environments. Here we applied PCR-DGGE method for molecular analysis of five soil nematode communities (designed as S1 to S5) collected from four provinces in Southeastern Vietnam (Binh Duong, Ba Ria Vung Tau, Binh Phuoc and Dong Nai) based on SSU gene. By sequencing DNA ...

  3. Theory of Multipartite Entanglement for X-States

    Science.gov (United States)

    2015-04-29

    Greenberger-Horne- Zeilinger (GHZ) state [9] and we explain below an approximation that reduces their density matrix to an X-state for all times. X-states...Blatt, Phys. Rev. Lett. 106, 130506 (2011). [9] D. Bouwmeester, J.-W. Pan, M. Daniell, H. Weinfurter, and A. Zeilinger , Phys. Rev. Lett. 82, 1345...Gasparoni, R. Ursin, G. Weihs, and A. Zeilinger , Nature (2003). [88] R. Dong, M. Lassen, J. Heersink, C. Marquardt, R. Filip, G. Leuchs, and U. L. Andersen

  4. CLEAR: Cross-Layer Exploration for Architecting Resilience

    Science.gov (United States)

    2017-03-01

    unavailable, or in an economy mode (low resilience, low power mode) when ABFT is available. However, the overheads outweigh benefits (details in [Cheng 16b...layer r Design, Automation , & Test in Europe, 2010. [Chen 05] Chen, Z. and J. Dong table real number codes based on random m Lecture Notes in...tolerate soft errors in processor c ACM/EDAC/IEEE Design Automation Conf., 2016. [Cheng 16b] Cheng, E., et al. -layer exploration for architecting

  5. OSA Imaging and Applied Optics Congress Support

    Science.gov (United States)

    2017-02-16

    Digest (online) (Optical Society of America, 20 16), paper JT3A .41. V. Katkovnik, "Sparse phase retrieval from noisy data: variational formulation and...A. Wojdyla, G. Gunjala, J. Dong, M. Benk, A. Neureuther, K. Goldberg , and L. Waller, "Off-axis Aberration Estimation in an EUV Microscope Using...2016, (Optical Society of America, 20 16), paper JT3A.41. V. Katkovnik, "Sparse phase retrieval from noisy data: variational formulation and algorithms

  6. Mixed Methods Approach to Identify Factors and the Extent to Which They Influence Medical/Surgical Prime Vendor Use

    Science.gov (United States)

    2014-03-27

    would not have been as enjoyable. I would also like to thank Col (ret) Don Faust, Col Duane Bragg and Lt Col (ret) Chris Canales for being...on the effectiveness of an IS utility in an organization (Dong, Neufeld, Higgins , 2009). Evidence suggests that top managers must adjust their...Neufeld, Higgins , 2009) and to advancements in organizational performance (Russell, Terborg, and Powers, 1985; Bartel, 1994; Knoke and Kalleberg, 1994

  7. Whole-genome sequence of Clostridium lituseburense L74, isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus

    OpenAIRE

    Lee, Yookyung; Lim, Sooyeon; Rhee, Moon-Soo; Chang, Dong-Ho; Kim, Byoung-Chan

    2016-01-01

    Clostridium lituseburense L74 was isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus collected in Yeong-dong, Chuncheongbuk-do, South Korea and subjected to whole genome sequencing on HiSeq platform and annotated on RAST. The nucleotide sequence of this genome was deposited into DDBJ/EMBL/GenBank under the accession NZ_LITJ00000000. Keywords: Insect, Larval gut, Whole genome shot-gun sequencing

  8. Whole-genome sequence of Clostridium lituseburense L74, isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus

    Directory of Open Access Journals (Sweden)

    Yookyung Lee

    2016-03-01

    Full Text Available Clostridium lituseburense L74 was isolated from the larval gut of the rhinoceros beetle, Trypoxylus dichotomus collected in Yeong-dong, Chuncheongbuk-do, South Korea and subjected to whole genome sequencing on HiSeq platform and annotated on RAST. The nucleotide sequence of this genome was deposited into DDBJ/EMBL/GenBank under the accession NZ_LITJ00000000. Keywords: Insect, Larval gut, Whole genome shot-gun sequencing

  9. Novel in situ self-assembly nanoparticles for formulating a poorly water-soluble drug in oral solid granules, improving stability, palatability, and bioavailability

    OpenAIRE

    Dong, Xiaowei; Guo,Shujie; Pham,Kevin; Li,Diana; Penzak,Scott

    2016-01-01

    Shujie Guo,1 Kevin Pham,2 Diana Li,2 Scott R Penzak,3 Xiaowei Dong2 1State Key Laboratory of Medical Genomics, Shanghai Key Laboratory of Hypertension, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 2Department of Pharmaceutical Sciences, 3Department of Pharmacotherapy, University of North Texas Health Science Center, Fort Worth, TX, USA Purpose: The purpose of this study was to develop a novel lipid-based nanotechnology to...

  10. Customer satisfaction comparison between Jingdong and Taobao

    OpenAIRE

    Zhang,Yehao

    2017-01-01

    Abstract: This study compares the customers satisfaction between two largest online shopping site Jingdong and taobao. Jing Dong (JD) is China's biggest online direct retailer by net stock volume. JD has the biggest satisfaction framework of any internet business organization in China. on the other hand Taobao is a Chinese web based shopping site like eBay, Amazon and Rakuten, which is worked in Hangzhou, Zhejiang by Alibaba Group. This study analyzed the customer satisfaction between tw...

  11. Assessment of Forest Degradation in Vietnam Using Landsat Time Series Data

    Directory of Open Access Journals (Sweden)

    James E. Vogelmann

    2017-07-01

    Full Text Available Landsat time series data were used to characterize forest degradation in Lam Dong Province, Vietnam. We conducted three types of image change analyses using Landsat time series data to characterize the land cover changes. Our analyses concentrated on the timeframe of 1973–2014, with much emphasis on the latter part of that range. We conducted a field trip through Lam Dong Province to develop a better understanding of the ground conditions of the region, during which we obtained many photographs of representative forest sites with Global Positioning System locations to assist us in our image interpretations. High-resolution Google Earth imagery and Landsat data of the region were used to validate results. In general, our analyses indicated that many land-use changes have occurred throughout Lam Dong Province, including gradual forest to non-forest transitions. Recent changes are most marked along the relatively narrow interfaces between agricultural and forest areas that occur towards the boundaries of the province. One important observation is that the most highly protected national reserves in the region have not changed much over the entire Landsat timeframe (1972–present. Spectral changes within these regions have not occurred at the same levels as those areas adjacent to the reserves.

  12. Featured Image: Simulating Planetary Gaps

    Science.gov (United States)

    Kohler, Susanna

    2017-03-01

    The authors model of howthe above disk would look as we observe it in a scattered-light image. The morphology of the gap can be used to estimate the mass of the planet that caused it. [Dong Fung 2017]The above image from a computer simulation reveals the dust structure of a protoplanetary disk (with the star obscured in the center) as a newly formed planet orbits within it. A recent study by Ruobing Dong (Steward Observatory, University of Arizona) and Jeffrey Fung (University of California, Berkeley) examines how we can determine mass of such a planet based on our observations of the gap that the planet opens in the disk as it orbits. The authors models help us to better understand how our observations of gaps might change if the disk is inclined relative to our line of sight, and how we can still constrain the mass of the gap-opening planet and the viscosity of the disk from the scattered-light images we have recently begun to obtain of distant protoplanetary disks. For more information, check out the paper below!CitationRuobing Dong () and Jeffrey Fung () 2017 ApJ 835 146. doi:10.3847/1538-4357/835/2/146

  13. Moldes contrários: o romantismo como modelo (negativo) para o naturalismo

    OpenAIRE

    DA SILVA, Alan Victor Flor; SALES, Germana Maria Araújo

    2014-01-01

    Modelos negativos são paradigmas com os quais não desejamos ser comparados, aos quais queremos nos contrapor ou dos quais esperamos ser diferentes. Considerando-se, portanto, esse conceito, a partir dos romances O Mulato (1881), de Aluísio de Azevedo, A Normalista (1893), de Adolfo Caminha, e Hortência (1888), de Marques de Carvalho, objetivamos, com este trabalho, demonstrar que os idealizadores do Naturalismo no Brasil atribuem ao Romantismo, ainda que de forma negativa, a função de modelo....

  14. O impacto das competências de marketing na definição de estratégia e as suas implicações na performance das empresas : um estudo em PME?s familiares portuguesas

    OpenAIRE

    Santos, Ana Catarina Damas dos

    2012-01-01

    Dissertação de mestrado em Marketing (Marketing Estratégico), apresentada à Faculdade de Economia da Universidade de Coimbra, sob a orientação de Arnaldo Coelho e Afonso Zinga. Este estudo tem como objectivo contribuir para o aprofundar do estudo das competências de marketing, investigando especificamente quais os factores que as influenciam, quais os reais impactos das competências na estratégia e quais as implicações na performance. Para testar estas premissas seleccionaram-se empresa...

  15. Bioactivity-Guided Identification of Botanical Inhibitors of Ketohexokinase.

    Science.gov (United States)

    Le, MyPhuong T; Lanaspa, Miguel A; Cicerchi, Christina M; Rana, Jatinder; Scholten, Jeffrey D; Hunter, Brandi L; Rivard, Christopher J; Randolph, R Keith; Johnson, Richard J

    2016-01-01

    In developed countries with westernized diets, the excessive consumption of added sugar in beverages and highly refined and processed foods is associated with increased risk for obesity, diabetes, and cardiovascular diseases. As a major constituent of added sugars, fructose has been shown to cause a variety of adverse metabolic effects, such as impaired insulin sensitivity, hypertriglyceridemia, and oxidative stress. Recent studies have shown that ketohexokinase isoform C is the key enzyme responsible in fructose metabolism that drive's fructose's adverse effects. The objective of this study was to identify botanical ingredients with potential for inhibitory activity against ketohexokinase-C and fructose-induced metabolic effects by using a series of in vitro model systems. Extracts from 406 botanicals and 1200 purified phytochemicals were screened (initial concentration of 50 μg/mL and 50 μM, respectively) for their inhibitory activity using a cell free, recombinant human ketohexokinase-C assay. Dose response evaluations were conducted on botanical extracts and phytochemicals that inhibited ketohexokinase-C by > 30% and > 40%, respectively. Two different extract lots of the top botanical candidates were further evaluated in lysates of HepG2 cells overexpressing ketohexokinase-C for inhibition of fructose-induced ATP depletion. In addition, extracts were evaluated in intact Hep G2 cells for inhibition of fructose-induced elevation of triglyceride and uric acid production. Among the botanical extracts, phloretin (Malus domestica) extracts were the most potent (IC50: 8.9-9.2 μg/mL) followed by extracts of Angelica archangelica (IC50: 22.6 μg/mL-57.3 μg/mL). Among the purified phytochemicals, methoxy-isobavachalcone (Psoralea corylifolia, IC50 = 0.2 μM) exhibited the highest potency against ketohexokinase isoform C activity followed by osthole (Angelica archangelica, IC50 = 0.7 μM), cratoxyarborenone E (Cratoxylum prunifolium, IC50 = 1.0 μM), and

  16. [Preparation and application on compound excipient of sodium stearyl fumarate and plasdone S-630].

    Science.gov (United States)

    Jiang, Yan-Rong; Zhang, Zhen-Hai; Jia, Xiao-Bin

    2013-01-01

    The compound excipient containing sodium stearyl fumarate and plasdone S-630 was prepared by applying spray drying method. The basic physical properties of compound excipient were studied by solubility test, scanning electron microscope, differential scanning calorimeter, X-ray diffraction and Fourier transform infra-red spectroscopy. The effect of compound excipient on moisture absorption and ferulic acid in vitro dissolution of spray drying power of angelica were investigated. The results showed that the chemical constituents of compound excipient did not change before and after spray drying. The water soluble compound excipient can improve significantly moisture absorption and has application prospect.

  17. Bioactivity-Guided Identification of Botanical Inhibitors of Ketohexokinase

    Science.gov (United States)

    Scholten, Jeffrey D.; Hunter, Brandi L.; Rivard, Christopher J.; Randolph, R. Keith

    2016-01-01

    Objective In developed countries with westernized diets, the excessive consumption of added sugar in beverages and highly refined and processed foods is associated with increased risk for obesity, diabetes, and cardiovascular diseases. As a major constituent of added sugars, fructose has been shown to cause a variety of adverse metabolic effects, such as impaired insulin sensitivity, hypertriglyceridemia, and oxidative stress. Recent studies have shown that ketohexokinase isoform C is the key enzyme responsible in fructose metabolism that drive’s fructose's adverse effects. The objective of this study was to identify botanical ingredients with potential for inhibitory activity against ketohexokinase-C and fructose-induced metabolic effects by using a series of in vitro model systems. Methods Extracts from 406 botanicals and 1200 purified phytochemicals were screened (initial concentration of 50 μg/mL and 50 μM, respectively) for their inhibitory activity using a cell free, recombinant human ketohexokinase-C assay. Dose response evaluations were conducted on botanical extracts and phytochemicals that inhibited ketohexokinase-C by > 30% and > 40%, respectively. Two different extract lots of the top botanical candidates were further evaluated in lysates of HepG2 cells overexpressing ketohexokinase-C for inhibition of fructose-induced ATP depletion. In addition, extracts were evaluated in intact Hep G2 cells for inhibition of fructose-induced elevation of triglyceride and uric acid production. Results Among the botanical extracts, phloretin (Malus domestica) extracts were the most potent (IC50: 8.9–9.2 μg/mL) followed by extracts of Angelica archangelica (IC50: 22.6 μg/mL—57.3 μg/mL). Among the purified phytochemicals, methoxy-isobavachalcone (Psoralea corylifolia, IC50 = 0.2 μM) exhibited the highest potency against ketohexokinase isoform C activity followed by osthole (Angelica archangelica, IC50 = 0.7 μM), cratoxyarborenone E (Cratoxylum prunifolium, IC

  18. Current knowledge from experimental works with radioprotective drugs from the viewpoint of latest scientific research; Aktualne poznatky z experiment8lnych prac s rastlinami s radioprotektivnym ucinkom vo svetle najnovsich vedeckych vyskumov

    Energy Technology Data Exchange (ETDEWEB)

    Skalka, J [Ustav vyzivy, dietetiky a krmovinarstva, Univerzita veterinarskeho lekarstva, 04181 Kosice (Slovakia)

    2008-06-15

    The protection of both human and animal population against a radiation impairment proves to be an impulse for continuous intensive searching for plants with radioprotective properties, identification of their radioprotective components and examination of their effects both in vivo an in vitro. I am presenting the results as well as knowledge of a latest scientific research in this field with testing the following plants: Vigna radiata, Mentha piperita, Citrus aurantium var. amara, Syzygium cumini, Tinospora cordifolia, Aegle marmelos, Phyllanthus amarus, Aloe vera, Angelica sinensis, Rosemarinus officinalis, Panax ginseng, Hippophae rhamnoides, Ocimum sanctum, Crataegus microphylla. (authors)

  19. Herbal Treatment in Menopause

    Directory of Open Access Journals (Sweden)

    Cigdem Gun

    2015-12-01

    Full Text Available The digest has been prepared to review available clinical evidence on herbs used in treatment of menopause symptoms. Effectiveness of Humulus lupulus, Vitex agnus-castus, Dioskorea vilosa, Linum usitatissimum, Pinus pinaster, cruciferous vegetables, Cimicifuga racemosa L., Angelica sinensis, Oenothera biennis L., Hypericum perforatum L., Panax ginseng, Ginkgo biloba, Glycine soja, Trifolium pratense and Piper methysticum herbs were assessed for treatment of menopausal symptoms in the studies. Herbs used as alternative supplementary treatment for menopause symptoms have been found to have a limited effect. Thus more studies are warranted to assess effectiveness of herbal treatments for menopausal symptoms. [Archives Medical Review Journal 2015; 24(4.000: 520-530

  20. Analytical Research to Determine the effects of the Components of ONGABO on the Viability of HepG2 Cancer Cells by Using the Sovereign, Minister, Assistant and Courier Principle (君臣佐使論

    Directory of Open Access Journals (Sweden)

    Shin Jeong-Hun

    2012-12-01

    Full Text Available Objectives: This study used the basic principle of Oriental medicine, the sovereign, minister, assistant and courier principle (君臣佐使論 to investigate the effects of the component of ONGABO, which is composed of Ginseng Radix (Red Ginseng, Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen and Curcumae tuber on the viability of HepG2 cells. Methods: Single and mixed extracts of the component of ONGABO were prepared by lypohilizing powder of Red Ginseng (6-year root from Kanghwa, Angelica Gigantis Radix, Schisandrae Fructus, Cuscuta Semen, Curcumae Tuber (from Omniherb Co., Ltd., Korea at the laboratory of herbal medicine in Woosuk University and were eluted after being macerated with 100% ethanol for three days. The cell viability of HepG2 was determined by using an absorptiometric analysis with PrestoBlue (Invitrogen reagent after the plate had been incubated for 48 hours. All of the experiments were repeated three times to obtain the average value and standard deviation. The statistical analysis was done and the correlation factor was obtained by using Microsoft Office Excel 2007 and Origin 6.0 software. Results: Although Ginseng Radix (Red Ginseng and Schisandrae Fructus did not enhance the viability of HepG2 cells, they were shown to provide protection of those cells. On the other hand, Angelica Gigantis Radix decreased the viability of HepG2 cells significantly, Cuscuta Semen and Curcumae Tuber had a small or no effect on the viability of HepG2 cells. Conclusions: In the sovereign, minister, assistant and courier principle (君臣佐使論, Ginseng Radix (Red Ginseng corresponds to the sovereign component because it provides cell protection effects, Angelica Gigantis Radix corresponds to minister medicinal because it kills cells, Schisandrae Fructus corresponds to the assistant medicinal to help red ginseng having cell protect effects. Cuscuta Semen and Curcumae Tuber correspond to the courier medicinal having no effect in

  1. Current knowledge from experimental works with radioprotective drugs from the viewpoint of latest scientific research

    International Nuclear Information System (INIS)

    Skalka, J.

    2008-01-01

    The protection of both human and animal population against a radiation impairment proves to be an impulse for continuous intensive searching for plants with radioprotective properties, identification of their radioprotective components and examination of their effects both in vivo an in vitro. I am presenting the results as well as knowledge of a latest scientific research in this field with testing the following plants: Vigna radiata, Mentha piperita, Citrus aurantium var. amara, Syzygium cumini, Tinospora cordifolia, Aegle marmelos, Phyllanthus amarus, Aloe vera, Angelica sinensis, Rosemarinus officinalis, Panax ginseng, Hippophae rhamnoides, Ocimum sanctum, Crataegus microphylla. (authors)

  2. Preventative Effect of an Herbal Preparation (HemoHIM) on Development of Airway Inflammation in Mice via Modulation of Th1/2 Cells Differentiation

    OpenAIRE

    Kim, Jong-Jin; Cho, Hyun Wook; Park, Hae-Ran; Jung, Uhee; Jo, Sung-Kee; Yee, Sung-Tae

    2013-01-01

    HemoHIM, an herbal preparation of three edible herbs (Angelica gigas Nakai, Cnidium officinale Makino, Paeonia japonica Miyabe) is known to increase the Th1 immune response as well as reduce the allergic response in human mast cells. Here, our goal was to determine whether or not HemoHIM could induce Th1 cell differentiation as well as inhibit the development of airway inflammation. To study Th1/Th2 cell differentiation, naive CD4(+) T cells isolated from C57BL/6 mouse spleens were cultured w...

  3. Giordano da Pisa and the language of angels

    Directory of Open Access Journals (Sweden)

    Alessia Francone

    2012-06-01

    Full Text Available Among the issues about the angels considered by the Dominican preacher Giordano da Pisa, this essay studies the problem of their language. The question of the locutio angelica had become quite relevant in the scholastic thought from the XIIIth century and had been widely discussed by Thomas Aquinas and Giles of Rome; the study of this argument in Giordano da Pisa’s sermons shows the transition in the homiletic texts of a highly speculative theme and we can see how the preacher, who combines rather freely the positions of Thomas and Giles, filters the question for his lay public, simplifying the more difficult passages.

  4. Studies on chemical protectors against radiation, 26

    International Nuclear Information System (INIS)

    Sato, Yushi; Ohta, Setsuko; Sakurai, Nobuko; Shinoda, Masato

    1989-01-01

    The protective potency against skin injury on mice induced by X-irradiation was studied by use of 72 extracts of crude drugs. The protective potency was determined according to the degrees of skin injury after irradiation of 1100 R, 30 kVp soft X-ray. As a result of this study, 16 kinds of crude drugs such as Rosae Fructus, Aloe arboresces (Herba), Citri Leiocarpae Exocarpium, Schizonepetae Spica, Evodiae Fructus, Bupleuri Radix, Corni Fructus, Perillae Herba, Anemarrhenae Rhizoma, Menthae Herba, Trapae Fructus, Angelicae Dahuricae Radix, Sinomeni Caulis et Rhizoma, Ephedrae Herba. Acer nikoense (Cortex), Forsythiae Fructus, revealed protective potencies on skin injury. (author)

  5. Study on the Chinese traditional drugs' sterilization and disinfestation by radiation and their biological effects

    International Nuclear Information System (INIS)

    Ma Shouxiang; Yang Ruikun; Liu Desheng

    1987-01-01

    The study of the sterilization and disinfestation by 60 Co γ-radiation and their biological effects on tuber of elevated gastrodia, Chinese angelica and Dangshen have been carried out. The experimental results show that optimal dose was 2 x 10 5 - 4 x 10 5 rad to kill insect in the three Chinese traditional drugs. The results also show that the content of the chemical composition of irradiated group is similar to control group under 6 x 10 5 rad. The thin-layer chromatography colour-maculae are almost the same. They have the same Rf exponent

  6. An Update on Antitumor Activity of Naturally Occurring Chalcones

    Directory of Open Access Journals (Sweden)

    En-Hui Zhang

    2013-01-01

    Full Text Available Chalcones, which have characteristic 1,3-diaryl-2-propen-1-one skeleton, are mainly produced in roots, rhizomes, heartwood, leaves, and seeds of genera Angelica, Sophora, Glycyrrhiza, Humulus, Scutellaria, Parartocarpus, Ficus, Dorstenia, Morus, Artocarpus, and so forth. They have become of interest in the research and development of natural antitumor agents over the past decades due to their broad range of mechanisms including anti-initiation, induction of apoptosis, antiproliferation, antimetastasis, antiangiogenesis, and so forth. This review summarizes the studies on the antitumor activity of naturally occurring chalcones and their underlying mechanisms in detail during the past decades.

  7. CO{sub 2} capture and utilization for enhanced oil recovery

    Energy Technology Data Exchange (ETDEWEB)

    Vilhelmsen, P.J.; Well, W. van; Nielsen, Charles [DONG Energy Generation, Fredericia (Denmark); Harrar, W.; Reffstrup, J. [DONG Energy Exploration and Production, Hoersholm (Denmark)

    2007-05-15

    CO{sub 2} is an international theme and the cap-and-trade systems under implementation will lead to significant alterations in the energy market and in the energy system altogether. A possible technical step to reduce atmospheric emissions is CO{sub 2} capture and the utilisation of the CO{sub 2} for Enhanced Oil Recovery (EOR). CO{sub 2} capture is to some extent a know technology but has not yet been optimised and commercialised for power plant utilisation. Correspondingly CO{sub 2} utilisation for EOR is a known method in other areas of the world where the reservoir conditions are different from those of the North Sea. For several years Elsam and Energi E2, part of DONG Energy, have worked on reducing CO{sub 2} emissions through increased efficiency at the coal-fired power plants, and this work has now been extended to also include capture and utilisation of CO{sub 2}. DONG E and P within DONG Energy has started work on the utilisation of CO{sub 2} for EOR at the company's fields in the North Sea. Based on DONG Energy's interest in working through the whole value chain from power plants to EOR utilisation in the North Sea, this paper describes our experience with CO{sub 2} capture at the trial plant CASTOR at Esbjerg power plant and the actual work of investigating and preparing the pilot test of CO{sub 2} for EOR in the North Sea. The paper also illustrates the perspectives of retrofitting the existing fleet of super critical coal-fired power plants close to the North Sea with CO{sub 2} capture and the utilisation of the CO{sub 2} for EOR in the North Sea. DONG Energy's perspective is that CO{sub 2} for EOR can contribute to materialising the vision that the central power plant can be developed into an energy refinery. The development work presented will be carried out in cooperation with leading international players and Danish universities and knowledge centres Technical University of Denmark (DTU), The Danish Geotechnical Institute (GEO) and Geological

  8. A Database Design for the Brazilian Air Force Flying Unit Operational Control System.

    Science.gov (United States)

    1984-12-14

    Company, 1980. 23. Pereira Filho, Jorge da Cunha " Banco de Dados Hoje" Dados e Ideias - Brazilian Magazine , 99 : 55-63 (February 1979). 24. Rich...34QUAIS SAO AS CONDICOES DE EMPREGO OPERACIONAL DO MIRAGE 2120 ?" LIKE "WHAT IS THE FORCESTATUS OF MIRAGE 2120?" % Parsed ! % [ Production added to system...4 - QUAIS SAO AS CONDICOES DE EMPREGO OPERACIONAL DO MIRAGE 2120 ? % Parsed ! % (S DEPLOC) = sbbr % (S-TIME) = 1000 % Endurance = 0200 % (SITCODE

  9. Chinese Herbal Formula, Modified Danggui Buxue Tang, Attenuates Apoptosis of Hematopoietic Stem Cells in Immune-Mediated Aplastic Anemia Mouse Model

    Directory of Open Access Journals (Sweden)

    Jingwei Zhou

    2017-01-01

    Full Text Available A derivative formula, DGBX, which is composed of three herbs (Radix astragali, Radix Angelicae sinensis, and Coptis chinensis Franch, is derived from a famous Chinese herbal formula, Danggui Buxue Tang (DBT (Radix astragali and Radix Angelicae sinensis. We aimed to investigate the effects of DGBX on the regulation of the balance between proliferation and apoptosis of hematopoietic stem cells (HSCs due to the aberrant immune response in a mouse model of aplastic anemia (AA. Cyclosporine (CsA, an immunosuppressor, was used as the positive control. Our results indicated that DGBX could downregulate the production of IFNγ in bone marrow cells by interfering with the binding between SLAM and SAP and the expressions of Fyn and T-bet. This herbal formula can also inhibit the activation of Fas-mediated apoptosis, interferon regulatory factor-1-induced JAK/Stat, and eukaryotic initiation factor 2 signaling pathways and thereby induce proliferation and attenuate apoptosis of HSCs. In conclusion, DGBX can relieve the immune-mediated destruction of HSCs, repair hematopoietic failure, and recover the hematopoietic function of HSCs in hematogenesis. Therefore, DGBX can be used in traditional medicine against AA as a complementary and alternative immunosuppressive therapeutic formula.

  10. [Features of Professor Ma Kun's medication in treating ovulatory infertility].

    Science.gov (United States)

    Tong, Ya-Jing; Zhang, Hui-Xian; Chen, Yan-Xia; Dong, Mei-Ling; Ma, Kun

    2017-12-01

    In order to analyze Professor Ma Kun's medication in treating anovulatory infertility, her prescriptions for treating anovulatory infertility in 2012-2015 were collected. The medication features and the regularity of prescriptions were mined by using traditional Chinese medicine inheritance support system, association rules, complex system entropy clustering and other mining methods. Finally, a total of 684 prescriptions and 300 kinds of herbs were screened out, with a total frequency of 11 156 times; And 68 core combinations and 8 new prescriptions were mined. The top three frequently used herbs by effect were respectively tonic herb, blood circulation promoting herb, and Qi-circulation promoting herb. The top three tastes were sweetness, bitterness and pungent flavor. The results showed 28 herbs with a high frequency of ≥100.The top 10 frequently used herbs were respectively Angelica Sinensis Radix, Cyperi Rhizoma, Chuanxiong Rhizome, Paeoniae Radix Rubra, Cyathulae Radix, Taxilli Herba, Cuscutae Semen, Codonopsis Radix, Ligustri Lucidi Fructus, Paeoniae Albaand Paeoniae Radix Alba. The association rules analysis showed commonly used herbal pairs, including Rehmanniae Radix Preparata-Chuanxiong Rhizome, Rehmanniae Radix Preparata-Angelica Sinensis Radix, Cuscutae Semen-Dipsaci Radix. In conclusion, Professor Ma has treated anovulatory infertility by nourishing the kidney and activating blood throughout the treatment course, and attached the importance to the relationship between Qi and blood and there gulation of liver, spleen and kidney in treating anovulatory infertility. Copyright© by the Chinese Pharmaceutical Association.

  11. Comparative analysis of Ligusticum chuanxiong and related umbelliferous medicinal plants by high performance liquid chromatography-electrospray ionization mass spectrometry.

    Science.gov (United States)

    Yi, Tao; Leung, Kelvin Sze-Yin; Lu, Guang-Hua; Zhang, Hao

    2007-04-01

    A highly precise and accurate method, based on high performance liquid chromatography-electrospray ionization mass spectrometry (HPLC-ESI-MS), was developed for the qualitative and quantitative comparison of the main constituents in the rhizome of Ligusticum chuanxiong (LC) and three related umbelliferous medicinal plants. A comprehensive validation of the developed method was conducted, and the method was highly sensitive, reproducible and accurate. The unique properties of the present method were validated by analyzing 20 related herbal samples including 5 LC samples, 5 Cnidium officinale samples (CO), 5 Angelica sinensis samples (AS) and 5 Angelica acutiloba samples (AA). Twelve compounds including phenolic constituents, alkylphthalides and phthalide dimers were identified by online ESI-MS and by comparison with literature data and standard compounds, and six of them were quantified by HPLC-DAD simultaneously. The results demonstrated that identical compound types were identified as the main constituents of LC, CO, AS and AA herbs. The results also support the alternative application of these medicinal plants in Chinese and Japanese folk medicines. In the present study, it was found that the variation in the abundance of senkyunolide A was significant in these related herbs; it is therefore feasible to choose senkyunolide A as a characteristic compound for quality evaluation and chemical authentication of these herbs.

  12. Oviposition inhibitor in umbelliferous medicinal plants for the common yellow swallowtail (Papilio machaon).

    Science.gov (United States)

    Morino, Chisato; Morita, Yusuke; Minami, Kazuki; Nishidono, Yuto; Nakashima, Yoshitaka; Ozawa, Rika; Takabayashi, Junji; Ono, Naoaki; Kanaya, Shigehiko; Tamura, Takayuki; Tezuka, Yasuhiro; Tanaka, Ken

    2018-01-01

    Umbelliferous medicinal plants, such as Angelica acutiloba Kitagawa and Angelica dahurica Bentham et Hooker filius ex Franchet et Savatier, account for a large percentage of crude drug consumption in Japan. The most serious problem in the cultivation of umbelliferous medicinal plants is the feeding damage caused by the common yellow swallowtail (Papilio machaon hippocrates C. & R. Felder, 1864). When we compared the numbers of eggs laid by P. machaon on six umbelliferous medicinal plants, the eggs on A. acutiloba, A. dahurica, and Glehnia littoralis Fr. Schmidt ex Miquel were the most numerous, those on Saposhnikovia divaricata Schischkin and Cnidium officinale Makino were rare, and Bupleurum falcatum Linné was not oviposited at all. To identify oviposition inhibitors for P. machaon in B. falcatum, S. divaricata, and C. officinale, the volatile chemical constituents of these umbelliferous medicinal plants were compared with GC-MS. We carried out multivariate analysis of gas chromatographic data and concluded that germacrene D, α-humulene, and trans-caryophyllene play important roles in protecting plants from oviposition by P. machaon. Their oviposition repellent activity was confirmed by the fact that the number of eggs laid on the leaves around a repellent device containing a mixture of germacrene D, α-humulene, and trans-caryophyllene was reduced by 40% compared to a control.

  13. Potential of Essential Oils as Penetration Enhancers for Transdermal Administration of Ibuprofen to Treat Dysmenorrhoea

    Directory of Open Access Journals (Sweden)

    Jun Chen

    2015-10-01

    Full Text Available The present study was conducted to evaluate and compare five essential oils (EOs as penetration enhancers (PEs to improve the transdermal drug delivery (TDD of ibuprofen to treat dysmenorrhoea. The EOs were prepared using the steam distillation method and their chemical compositions were identified by GC-MS. The corresponding cytotoxicities were evaluated in epidermal keartinocyte HaCaT cell lines by an MTT assay. Furthermore, the percutaneous permeation studies were carried out to compare the permeation enhancement effect of EOs. Then the therapeutic efficacy of ibuprofen with EOs was evaluated using dysmenorrheal model mice. The data supports a decreasing trend of skin cell viability in which Clove oil >Angelica oil > Chuanxiong oil > Cyperus oil > Cinnamon oil >> Azone. Chuanxiong oil and Angelica oil had been proved to possess a significant permeation enhancement for TDD of ibuprofen. More importantly, the pain inhibitory intensity of ibuprofen hydrogel was demonstrated to be greater with Chuanxiong oil when compared to ibuprofen without EOs (p < 0.05. The contents of calcium ion and nitric oxide (NO were also significantly changed after the addition of Chuanxiong oil (p < 0.05. In summary, we suggest that Chuanxiong oil should be viewed as the best PE for TDD of ibuprofen to treat dysmenorrhea.

  14. Prescription Pattern of Chinese Herbal Products for Breast Cancer in Taiwan: A Population-Based Study

    Directory of Open Access Journals (Sweden)

    Jung-Nien Lai

    2012-01-01

    Full Text Available Background. Chinese herbal products (CHPs given as a therapy for symptom relief have gained widespread popularity among women with breast cancer. The aim of this study was to analyze the utilization of CHP among women with breast cancer in Taiwan. Methods. The usage, frequency of services, and CHP prescribed for breast cancer among women with breast cancer were evaluated, recruited from a randomly sampled cohort of 1,000,000 beneficiaries from the National Health Insurance Research Database. The logistic regression method was employed to estimate the odds ratios (ORs for utilization of CHP. Results. 81.5 percent (N=2,236 of women with breast cancer utilized traditional Chinese medicine (TCM and 18% of them sought TCM with the intent of treating their breast cancer. Jia-wei-xiao-yao-san (Augmented Rambling Powder was the most frequently prescribed formula for treating breast cancer. Among the top 10 most frequently prescribed CHP for treating breast cancer, seven contained dang qui (Angelica sinensis-radix and six contained ren shen (Panax ginseng-radix, which are reported to have potential beneficial synergistic effects on breast cancer cells. Conclusion. CHP containing dang qui (Angelica sinensis-radix or ren shen (Panax ginseng-radix are the most frequently prescribed for breast cancer and their effects should be taken into account by healthcare providers.

  15. The polymorphism of the Knops blood group system among five Chinese ethnic groups.

    Science.gov (United States)

    Li, Qin; Han, Sha-Sha; Guo, Zhong-Hui; Yang, Ying; Zhou, Jie; Zhu, Zi-Yan

    2010-12-01

    This work aims to explain the complexity of the Knops blood group system in the Chinese population. The Knops blood group system consists of antigens encoded by CR1 gene exon 29. A total of 281 individuals from the Han, Uigur, Tu, Lisu and Dong ethnic groups were studied. The coding region of the CR1 gene of 11 Han donors was analysed using reverse transcription-polymerase chain reaction (PCR) and sequencing. CR1 gene exon 29 in the 39 samples was analysed through genomic DNA sequencing. According to the sequencing result, a PCR-sequence-specific primers system was designed to screen the A4646G and A4870G alleles in the Chinese population. Twelve single nucleotide polymorphisms (SNPs) were observed in the coding region of the CR1 gene in the Han population. Two SNPs (A4646G and A4870G) were detected in the CR1 gene exon 29. The 4646G allele was found only in the Uigur and Tu ethnic groups, in which the allele frequencies were 0·11 and 0·06, respectively. The frequencies of the 4870A allele in the Han, Uigur, Tu, Lisu and Dong ethnic groups were 0·82, 0·83, 0·82, 0·57 and 0·57, respectively. The CR1 gene in the Chinese people is more conservative than that in the Caucasian or African people. Different Chinese ethnic groups may have their own different CR1 gene characteristics. The existence of 4646G in the Uigur and Tu ethnic groups suggests that both may carry certain Caucasian characteristics in the CR1 gene. The frequency of 4870G in the Lisu and Dong ethnic groups implies possible incidence of evolutionary pressure similar to what the Africans had experienced. © 2010 The Authors. Transfusion Medicine © 2010 British Blood Transfusion Society.

  16. Assessment of polycyclic aromatic hydrocarbons (PAHs) pollution in soil of suburban areas in Tianjin, China.

    Science.gov (United States)

    Lv, Jungang; Shi, Rongguang; Cai, Yanming; Liu, Yong

    2010-07-01

    Soil contamination with polycyclic aromatic hydrocarbons is an increasing problem and has aroused more and more concern in many countries, including China. In this study, representative soil samples (n = 87) of suburban areas in Tianjin (Xiqing, Dongli, Jinnan, Beichen) were evaluated for 16 polycyclic aromatic hydrocarbons. Surface soil samples were air-dried and sieved. Microwave assisted extraction was used for polycyclic aromatic hydrocarbons preparation prior to analysis with gas chromatography-mass spectrometry. The total concentrations of tested polycyclic aromatic hydrocarbons in Xiqing, Dongli, Jinnan, Beichen ranged in 58.5-2,748.3, 36.1-6,734.7, 58.5-4,502.5, 29.7-852.5 ng/g and the averages of total concentration of polycyclic aromatic hydrocarbons were 600.5, 933.6, 640.8, 257.3 ng/g, respectively. Spatial variation of polycyclic aromatic hydrocarbons in soil was illustrated; Pollution status and comparison to other cities were also investigated. Serious polycyclic aromatic hydrocarbons soil pollution was found in Dongli district, on the contrary, Bap in most sites in Beichen did not exceed relative standards and most sites in Beichen should be classified as non-contaminated soil. Principal component analysis was used to identify the possible sources of different districts. It turned out that coal combustion still was the most important sources in three districts except Beichen. Coking, traffic, cooking, biomass combustion also accounted for polycyclic aromatic hydrocarbons pollution to certain extent in different districts. These data can be further used to assess the health risk associated with soils polluted with polycyclic aromatic hydrocarbons and help local government find proper way to reduce polycyclic aromatic hydrocarbons pollution in soils.

  17. Pilot Comparative Case Study on Eco-innovation Dynamics at firm level

    DEFF Research Database (Denmark)

    Yang, Yan; Du, Xiangyun; SHAO, Yunfei

    2010-01-01

    This paper pays special attention to eco-innovations dynamics at firm level. Triple helix twins are employed to disclose the complex collaborations within and across the case companies, as it provides us the possibilities of looking beyond the simpler, linear model of innovation and. Grundfos...... and environmental regulations. Dong Fang (China) is identified as a company at the very beginning of eco-innovation, as its compliance with environmental standards such as ISO 9001, ISO14001, OHSAS 18001 is absent at present; its collaborations with government and universities or research institutions...... helix twins and eco-innovation dynamics is addressed....

  18. Command History. 1967. Volume 1. Sanitized

    Science.gov (United States)

    1967-01-01

    the Politburo of the Lao Dong Party. This top political control center included Le Duan, General Vo Nguyen Glap, Truong Chinh , Le Duc Tho, and until...the support area Naval Support Activity (NSA) Da Nang’s vital intra- coastal trans -shipment route from the deep water port at Da Nang northward to...under the energetic guidance of MG Nguyen Duc Thang, reviewed PAGE 6 OF 1340 PAGES I% the entire process of RD and set to the task of revitalizing the

  19. Essays on Strategy. 5

    Science.gov (United States)

    1988-01-01

    Van Dong, Truong Chinh , To Huu, and Le Duc Tho, but retained and pro- moted to the number two position Pham Hung, the Min- ister of Interior and one...explained that a basic concern of the United States was that the Pacific region Should not be trans - formed "into yet another area of superpower confronta... tran - ,sition to mutual 13Mll) t’apkailities would be frought with uncertainty, instabilitY, and po-,ible peril. ("On.juentlvt. alternative tour vields

  20. 現代中国における伝統主義と権威構造 : 毛沢東は如何に"出題"されるか

    OpenAIRE

    鐙屋, 一; Hajime, Abumiya; 目白大学外国語学部アジア語学科

    2006-01-01

    On December 26 1993, the hundredth anniversary of his birth, Mao Ze-dong was made the subject of a quiz competition held at Beijing Normal University. The mere fact that Mao was treated in this way made it clear that his status was no longer that of a sacred and inviolable being. After the June 4th Tiananmen Square incident in 1989, a structural change in the nature of authority was brought about by the growth of traditionalism, which made a fetish of the Revolution of Modern China and acted ...

  1. Enhanced methanol oxidation and oxygen reduction reactions on palladium-decorated FeCo@Fe/C core–shell nanocatalysts in alkaline medium

    CSIR Research Space (South Africa)

    Fashedemi, OO

    2013-12-01

    Full Text Available . Zhong, J. Luo, B. Fang, B. N. Wanjala, P. N. Njoki, R. Loukrakpam and J. Yin, Nanotechnology, 2010, 21, 062001. 39 C. L. Lee, H. P. Chiou, C. M. Syu, C. R. Liu, C. C. Yang and C. C. Syu, Int. J. Hydrogen Energy, 2011, 36, 12706–12714. 40 K. J. Mayrhofer..., 12, 1102–1106. 2 Y. W. Lee, M. Kim, Y. Kim, S. W. Kang, J. H. Lee and S. W. Han, J. Phys. Chem. C, 2010, 114, 7689–7693. 3 C. Zhu, S. Guo and S. Dong, J. Mater. Chem., 2012, 22, 14851–14855. 4 C. Jeyabharathi, P. Venkateshkhumar, J. Mathiyarasau and K...

  2. On Propagating Requirements and Selecting Fuels for a Benson Boiler

    DEFF Research Database (Denmark)

    Kragelund, Martin Nygaard; Wisniewski, Rafal; Mølbak, Tommy

    2008-01-01

    In this paper, the problem of optimal choice of sensors and actuators is addressed. Given a functional encapsulating information of the desired performance and production economy the objective is to choose a control instrumentation from a given set to comply with its minimum. The objective of the...... to propagate a global objective to local subsystems. Particular focus is on a boiler in a power plant operated by Dong Energy. The business objectives have been propagated to the actuator level to allow for selection of an actuator configuration....

  3. Biological age as a health index for mortality and major age-related disease incidence in Koreans: National Health Insurance Service – Health screening 11-year follow-up study

    OpenAIRE

    Kang,Young Gon; Suh,Eunkyung; Lee,Jae-woo; Kim,Dong Wook; Cho,Kyung Hee; Bae,Chul-Young

    2018-01-01

    Young Gon Kang,1 Eunkyung Suh,2 Jae-woo Lee,3 Dong Wook Kim,4 Kyung Hee Cho,5 Chul-Young Bae1 1Department of R&D, MediAge Research Center, Seongnam, Republic of South Korea; 2Department of Family Medicine, College of Medicine, CHA University, Chaum, Seoul, Republic of South Korea; 3Department of Family Medicine, College of Medicine, Chungbuk National University, Cheongju, Republic of South Korea; 4Department of Policy Research Affairs, National Health Insurance Service Ilsan Hospital...

  4. JPRS Report China

    Science.gov (United States)

    1989-12-19

    Japanese Investment 90OH0029A Beijing GUOJIMAOYI WENTI [INTERNATIONAL TRADE JOURNAL ] in Chinese No 7-8, 30Aug89pp 12-14 [Article by Zhang Dong...beginning of July showed that in recent years the practice of building private homes by cadres has flour - ished, with two-thirds of the cities and...the mess hall; and the money for the fountain pen ink and for glue used by the cadres came from the individual’s own pocket. Once, Young Jiang

  5. Browse Author Index - AJOL

    African Journals Online (AJOL)

    Items 51 - 100 of 222 ... G. Gökçekuş, Laika · Gökbulut, Alper · Gönüllü, Ü · Gören, Ahmet C. Gümüstas, Aysen · Gürpınar, P · Güzel, Y · Gbeassor, M · Gbeassor, M · Gbeassor, Messanvi · Ge, Jian-Jun · Ge, Liangpeng · Ge, Yingliang · Geetha, M · Gelisen, Ilker · Geng, Dong-mei · Geng, S · Geng, W · Geng, Xiu-Li · Geng, Yumei

  6. Blood on the Stone : Greed, Corruption and War in the Global ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    15 août 2010 ... ... du seigneur de la guerre libérien Charles Taylor. Il a été l'un des principaux représentants d'ONG ayant pris part au processus de Kimberley depuis les débuts jusqu'à sa démission en 2009. Ian Smillie a été nommé officier de l'Ordre du Canada en 2003. Edición español: Leer e-libro / Descargar PDF ...

  7. Preface: Ecosystem services, ecosystem health and human communities

    Science.gov (United States)

    Plag, Hans-Peter

    2018-04-01

    This special issue contains a collection of manuscripts that were originally intended to be included in the special issue on "Physics and Economics of Ecosystem Services Flows" (Volume 101, guest editors H. Su, J. Dong and S. Nagarajan) and "Biogeochemical Processes in the Changing Wetland Environment" (Volume 103, guest editors J. Bai, L. Huang and H. Gao). All of them are addressing issues related to ecosystem services in different settings. Ecosystem services are of high value for both the ecosystems and human communities, and understanding the impacts of environmental processes and human activities on ecosystems is of fundamental importance for the preservation of these services.

  8. Role of Heterotrophic Bacteria in Marine Ecological Processes

    Digital Repository Service at National Institute of Oceanography (India)

    Ramaiah, N.

    radicals (called reactive oxygen species) and ferric ion concentrations are known to exert significant influence on bacterial growth (Koga and Takumi, 1995; Gauthier, 2000; Ji-Dong Gu, Chapter 7). Most of these agents in aquatic environment can cause death... are then developed into the fossil fuels and extracted as oil and gas to drive the world?s economy. The burning of fossil fuel releases large quantities of CO2 into the atmosphere, which may accumulate over time or can be incorporated into plant material...

  9. Harmonic modelling, propagation and mitigation for large wind power plants connected via long HVAC cables

    DEFF Research Database (Denmark)

    Dowlatabadi, Mohammadkazem Bakhshizadeh; Hjerrild, Jesper; Kocewiak, Łukasz

    2016-01-01

    This paper presents a state-of-the-art review on grid connection of large offshore wind power plants (OWPPs) using extra-long high voltage AC (HVAC) cables. The paper describes research by DONG Energy Wind Power in close collaboration with Aalborg University addressing related challenges through...... an industrial PhD project. The overall goal is to gain a better understanding of extra-long HVAC cable connected OWPPs, in order to ensure reliability and availability of OWPPs. This will reduce the cost of energy, as the risk of costly delays and modifications after the project has been commissioned can...

  10. The Chemical Constituents and Pharmacological Actions of Cordyceps sinensis

    Science.gov (United States)

    Liu, Yi; Wang, Jihui; Wang, Wei; Zhang, Hanyue; Zhang, Xuelan; Han, Chunchao

    2015-01-01

    Cordyceps sinensis, also called DongChongXiaCao (winter worm, summer grass) in Chinese, is becoming increasingly popular and important in the public and scientific communities. This study summarizes the chemical constituents and their corresponding pharmacological actions of Cordyceps sinensis. Many bioactive components of Cordyceps sinensis have been extracted including nucleoside, polysaccharide, sterol, protein, amino acid, and polypeptide. In addition, these constituents' corresponding pharmacological actions were also shown in the study such as anti-inflammatory, antioxidant, antitumour, antiapoptosis, and immunomodulatory actions. Therefore can use different effects of C. sinensis against different diseases and provide reference for the study of Cordyceps sinensis in the future. PMID:25960753

  11. Macrosolen bidoupensis (Loranthaceae, a new species from Bidoup Nui Ba National Park, southern Vietnam

    Directory of Open Access Journals (Sweden)

    Shuichiro Tagane

    2017-06-01

    Full Text Available Macrosolen bidoupensis Tagane & V.S.Dang, sp. nov. (Loranthaceae is newly described from Bidoup Nui Ba National Park in Lam Dong Province, southern Vietnam. The new species is characterized by small broadly elliptic to circular leaves, sessile to short petioles, slightly cordate to rounded leaf bases, 4–5 pairs of lateral veins and a basally green corolla tube. An illustration, a summary of DNA barcoding of the plastid genes rbcL and matK, and a key to the species of Macrosolen in Vietnam are provided.

  12. Hen til kommoden

    DEFF Research Database (Denmark)

    Rüdiger, Mogens

    2002-01-01

    The article is about some of the main problems connected with the introduction of natural gas in Denmark. As the Danish population turned down nuclear power in the 1970s, natural gas became an important part of the government's efforts to establish a differentiated energy supply. This innovative...... gas business. As a member of the EEC in the late 1980s Denmark met with the obligation to liberalize the energy system. In the light of this task the article discusses the political demand for privatisation of DONG and - more importantly - the relation between price, security of supply and public...

  13. Horns Rev II, 2-D Model Tests

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Frigaard, Peter

    This report present the results of 2D physical model tests carried out in the shallow wave flume at Dept. of Civil Engineering, Aalborg University (AAU), on behalf of Energy E2 A/S part of DONG Energy A/S, Denmark. The objective of the tests was: to investigate the combined influence of the pile...... diameter to water depth ratio and the wave hight to water depth ratio on wave run-up of piles. The measurements should be used to design access platforms on piles....

  14. Interdicting an Adversary’s Economy Viewed As a Trade Sanction Inoperability Input Output Model

    Science.gov (United States)

    2017-03-01

    Agriculture, hunting, forestry and fishing YES $4,578,424,000 2 TTL_C10T14: Mining and quarrying YES $53,345,194,000 3 TTL_C15T16: Food products, beverages ...22202-4302, and to the Office of Management and Budget, Paperwork Reduction Project (0704-0188) Washington, DC 20503. 1. AGENCY USE ONLY (Leave...Wei, Dong, and Sun (2009) use the IIM to study supply chain risk management and mitigation strategies. They use a method called the “ordered

  15. Drug–drug interaction of microdose and regular-dose omeprazole with a CYP2C19 inhibitor and inducer

    OpenAIRE

    Park G; Bae SH; Park W; Han S; Park M; Shin S; Shin YG; Yim DS

    2017-01-01

    Gab-jin Park,1 Soo Hyeon Bae,1 Wan-Su Park,1 Seunghoon Han,1 Min-Ho Park,2 Seok-Ho Shin,2 Young G Shin,2 Dong-Seok Yim1,2 1Department of Clinical Pharmacology and Therapeutics, Seoul St Mary’s Hospital, PIPET (Pharmacometrics Institute for Practical Education and Training), College of Medicine, Catholic University of Korea, Seoul, South Korea; 2College of Pharmacy, Chungnam National University, Daejeon, South Korea Purpose: A microdose drug–drug interaction (DDI) study may be a ...

  16. Wheat straw, household waste and hay as a source of lignocellulosic biomass for bioethanol and biogas production

    DEFF Research Database (Denmark)

    Tomczak, Anna; Bruch, Magdalena; Holm-Nielsen, Jens Bo

    2010-01-01

    To meet the increasing need for bioenergy three lignocellulosic materials: raw hay, pretreated wheat straw and pretreated household waste were considered for the production of bioethanol and biogas. Several mixtures of household waste supplemented with different fractions of wheat straw and hay...... in fermentation process with Saccharomyces cerevisiae were investigated. Wheat straw and household wastes were pretreated using IBUS technology, patented by Dong Energy, which includes milling, stem explosion treatment and enzymatic hydrolysis. Methane production was investigated using stillages, the effluents...... from bioethanol fermentation experiment. Previous trial of biogas production from above mentioned household wastes was enclosed....

  17. Pharmacokinetic and bioequivalence study of a telmisartan/S-amlodipine fixed-dose combination (CKD-828) formulation and coadministered telmisartan and S-amlodipine in healthy subjects

    OpenAIRE

    Kang,Woo Youl; Seong,Sook Jin; Ohk,Boram; Gwon,Mi-Ri; Kim,Bo Kyung; La,Sookie; Kim,Hyun-Ju; Cho,Seungil; Yoon,Young-Ran; Yang,Dong Heon; Lee,Hae Won

    2018-01-01

    Woo Youl Kang,1,2,* Sook Jin Seong,1,* Boram Ohk,1,2 Mi-Ri Gwon,1,3 Bo Kyung Kim,1,2 Sookie La,4 Hyun-Ju Kim,3 Seungil Cho,1 Young-Ran Yoon,1,2 Dong Heon Yang,5 Hae Won Lee1 1Clinical Trial Center, Kyungpook National University Hospital, Daegu, Republic of Korea; 2Department of Biomedical Science, BK21 Plus KNU Bio-Medical Convergence Program for Creative Talent, Kyungpook National University Graduate School, Daegu, Republic of Korea; 3Department of Molecular Medicine, Cell and Matrix Resear...

  18. First observation on the breeding behavior of endangered species, Chinese many-tooth snake, Sibynophis chinensis

    Directory of Open Access Journals (Sweden)

    Kyo Soung Koo

    2018-06-01

    Full Text Available We report the first observation of reproductive behavior of endangered snake, Sibynophis chinensis in South Korea. On September 24, 2014, one female and three males were observed during the group mating in Oedo-dong, Jeju. Our observation indicates that group mating and the breeding behavior of S. chinensis could be an important way to increase genetic diversity and survival rate. Moreover, autumnal mating affects the breeding success rate of species in isolated areas. Group and autumn mating strategies by S. chinensis are considered to be the most effective way to survive in isolated areas.

  19. Electric Power Research in 1991

    International Nuclear Information System (INIS)

    1991-05-01

    This book of contents are a study of desalination by Kim, Young Bu, a study on efficiency test for nuclear power security by Jo, Sung Je; Ann, Nam Sung; Kim, Ho Gi, augmentation of EMS and RYU by Jung, Tae Hoe; Shin, Young Chuel, research on application for electric cars by Yu, Ann Gue, practical use oft robot for nuclear industry by Woo, He Gone; Shin, Hen Beom, a study on the characteristics of coolant structure in generator by Choi, Beng Hwan; Song, Young Chel; Kim, Jong Hark, and research of penetration rate of appliances by Park, Hong Ho; Kim, Beng Cheal; Kim, Dong Hwen.

  20. Photoluminescent (PL) or electroluminescent (EL) quantum dots for display, lighting, and photomedicine (Conference Presentation)

    Science.gov (United States)

    Dong, Yajie

    2017-02-01

    Quantum dots (QDs) have gone through a long journey before finding their ways into the display field. This talk will briefly touch on the history before trying to answer several key questions related to QDs applications in display: What are QDs? How are they made? What properties do they have and Why? How can these properties be used to improve color and efficiency of display, in either photoluminescence (PL) or electroluminescence (EL) mode? And what are the remaining challenges for QDs wide adoption in display industry? Lastly, some most recent progresses in our UCF lab at both PL and EL fronts will be highlighted. For PL, a cadmium-free perovskite-polymer composite films with exceptionally narrow emission green peaks (FWHM 20 nm) and good water and thermal stability will be reported. Together with red quantum dots or PFS/KSF phosphors as down-converters for blue LEDs, a white-light source with 95% Rec. 2020 color gamut was demonstrated [1]. For EL, red quantum dot light emitting devices (QLEDs) with record luminance of 165,000 Cd/m2 has been obtained at a current density of 1000 mA/cm2 with a low driving voltage of 5.8 V and CIE coordinates of (0.69, 0.31). [2] The potential of using these QLEDs for light sources for integrated sensing platform [3] or high efficiency, high color quality hybrid white OLED [4] will be discussed. [1] Y. N. Wang, J. He, H. Chen, J. S. Chen, R. D. Zhu, P. Ma, A. Towers, Y. Lin, A. J. Gesquiere, S. T. Wu, Y. J. Dong. Ultrastable, Highly Luminescent Organic-Inorganic Perovskite - Polymer Composite Films, Advanced Materials, accepted, (2016). [2] Y. J. Dong, J.M. Caruge, Z. Q. Zhou, C. Hamilton, Z. Popovic, J. Ho, M. Stevenson, G. Liu, V. Bulovic, M. Bawendi, P. T. Kazlas, S. Coe-Sullivan, and J. Steckel Ultra-bright, Highly Efficient, Low Roll-off Inverted Quantum-Dot Light Emitting Devices (QLEDs). SID Symp. Dig. Tech. Pap. 46, 270-273 (2015). [3] J. He, H. Chen, S. T. Wu, and Y. J. Dong, Integrated Sensing Platform Based on Quantum

  1. Comparative steady-state pharmacokinetic study of an extended-release formulation of itopride and its immediate-release reference formulation in healthy volunteers

    OpenAIRE

    Yoon, Seonghae; Lee, Howard; Kim, Tae-Eun; Lee, SeungHwan; Chee, Dong-Hyun; Cho, Joo-Youn; Yu, Kyung-Sang; Jang, In-Jin

    2014-01-01

    Seonghae Yoon,1,* Howard Lee,2,* Tae-Eun Kim,1 SeungHwan Lee,1 Dong-Hyun Chee,3 Joo-Youn Cho,1 Kyung-Sang Yu,1 In-Jin Jang1 1Department of Clinical Pharmacology and Therapeutics, Seoul National University College of Medicine and Hospital, 2Clinical Trials Center, Seoul National University Hospital, 3AbbVie Ltd., Seoul, Republic of Korea *These authors contributed equally to this work Background: This study was conducted to compare the oral bioavailability of an itopride extended-release (ER...

  2. A System for Fast Navigation of Autonomous Vehicles

    Science.gov (United States)

    1991-09-01

    AD-A243 523 4, jj A System for Fast Navigation of Autonomous Vehicles Sanjiv Singh, Dai Feng, Paul Keller, Gary Shaffer, Wen Fan Shi, Dong Hun Shin...FUNDING NUMBERS A System for Fast Navigation of Autonomous Vehicles 6. AUTHOR(S) S. Singh, D. Feng, P. Keller, G. Shaffer, W.F. Shi, D.H. Shin, J. West...common in the control of autonomous vehicles to establish the necessary kinematic models but to ignore an explicit representation of the vehicle dynamics

  3. Anti-RhoC siRNAs inhibit the proliferation and invasiveness of breast cancer cells via modulating the KAI1, MMP9, and CXCR4 expression

    OpenAIRE

    Xu, Xu-Dong; Shen, Han-Bin; Zhu, Li; Lu, Jian-Qin; Zhang, Lin; Luo, Zhi-Yong; Wu, Ya-Qun

    2017-01-01

    Xu-Dong Xu,1 Han-Bin Shen,1 Li Zhu,2 Jian-Qin Lu,2 Lin Zhang,3 Zhi-Yong Luo,3 Ya-Qun Wu3 1Department of Thyroid and Breast Surgery, The Fifth Hospital of Wuhan, Hanyang District, 2Department of Oncology, 3Department of Thyroid and Breast Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, People’s Republic of China Abstract: Overexpression of RhoC in breast cancer cells indicates poor prognosis. In the present study, we ai...

  4. Key energy technologies for Europe

    DEFF Research Database (Denmark)

    Jørgensen, B.H.

    2005-01-01

    This report on key energy technologies is part of the work undertaken by the High-Level Expert Group to prepare a report on emerging science and technology trends and the implications for EU and Member State research policies. Senior Scientist BirteHolst Jørgensen, Risø National Laboratory...... contributed by Scientific Officer Edgar Thielmann, DG TREN, Head of Department Hans Larsen, RisøNational Laboratory, Senior Asset Manager Aksel Hauge Pedersen, DONG VE, Consultant Timon Wehnert, IZT-Berlin, and Senior Scientist Martine Uyterlinde, ECN...

  5. Anholt offshore wind farm winds investigated from satellite images

    DEFF Research Database (Denmark)

    Hasager, Charlotte Bay; Badger, Merete; Volker, Patrick

    , i.e. before the wind farm was constructed. Based on these data the wind resource is estimated. Concurrent Sentinel-1 SAR data and available SCADA and lidar data, kindly provided by DONG Energy and partners, for the period January 2013 to June 2015 account for ~70 images, while ~300 images...... are available for Sentinel-1 from July 2015 to February 2017. The Sentinel-1 wind maps are investigated for wind farm wake effects. Furthermore the results on wind resources and wakes are compared to the SCADA and model results from WRF, Park, Fuga and RANS models....

  6. A Method to Measure the Amount of Battlefield Situation Information

    Science.gov (United States)

    2014-06-01

    log)( 20 atS  3.2 Measurement of trends information Kierkegaard once said “Life can only be understood backwards, but it must be lived forwards” [8...Towards a theory of s 10 11 , “The Journals of Soren Kierkegaard ”, A selection and translated by Alexander chun, “Formal Description of Command...and 37(2), pp32-64, 1995. [8] Kierkegaard , Soren – Dru , Oxford: Oxford University Press (1938). pp465 [9] ZHOU Dao-an, ZHANG Dong-ge, CHANG Shu

  7. Drug-resistant colon cancer cells produce high carcinoembryonic antigen and might not be cancer-initiating cells

    OpenAIRE

    Lee HC; Ling QD; Yu WC; Hung CM; Kao TC; Huang YW; Higuchi A

    2013-01-01

    Hsin-chung Lee,1,2 Qing-Dong Ling,1,3 Wan-Chun Yu,4 Chunh-Ming Hung,4 Ta-Chun Kao,4 Yi-Wei Huang,4 Akon Higuchi3–51Graduate Institute of Systems Biology and Bioinformatics, National Central University, Jhongli, Taoyuan, 2Department of Surgery, Cathay General Hospital, Da'an District, Taipei, 3Cathay Medical Research Institute, Cathay General Hospital, Hsi-Chi City, Taipei, 4Department of Chemical and Materials Engineering, National Central University, Jhongli, Taoyuan, Taiwa...

  8. A Highly Responsive Silicon Nanowire/Amplifier MOSFET Hybrid Biosensor

    Science.gov (United States)

    2015-07-21

    Hybrid Biosensor Jieun Lee1,2, Jaeman Jang1, Bongsik Choi1, Jinsu Yoon1, Jee-Yeon Kim3, Yang-Kyu Choi3, Dong Myong Kim1, Dae Hwan Kim1 & Sung-Jin Choi1...This study demonstrates a hybrid biosensor comprised of a silicon nanowire (SiNW) integrated with an amplifier MOSFET to improve the current response...of field-effect-transistor (FET)-based biosensors . The hybrid biosensor is fabricated using conventional CMOS technology, which has the potential

  9. Transition écologique d'un modèle d'innovation : la production de semences d'ignames en Haïti

    OpenAIRE

    Boyer, James; Temple, Ludovic

    2017-01-01

    Cet article montre comment le passage d'un modèle linéaire de l'innovation à un processus itératif, participatif et écologique modifie une technologie et permet de réaliser son adoption dans l'agriculture. Le cas d'étude est basé sur une technologie de multiplication de semences d'ignames en Haïti, la technique Miniset. Nous analysons l'évolution de cette technique au cours de la période 1990-2012 en mobilisant des entrevues avec 26 experts (chercheurs, techniciens, responsables d'ONG, agricu...

  10. People who live for quality

    International Nuclear Information System (INIS)

    1995-03-01

    This book introduces the case of model of quality management. There are a lot of titles and people's example such as with dogged perseverance by Kang, Beom Sik in SK industry, come back to company which he submitted his resignation by Kim, Byeong Hui in Hyundai Heavy industries, I want to be the world best by Yeon, Sang Jin in Geum Ho industry, a good beginning is half the battle by Kwon, Bok Sik in KIA company, employee satisfaction is quality management by Hong, Sun Gyeom, in Dong Yang piston, and praying for all by Kim, Youn Ja in Lotte department store.

  11. Porous and Phase Change Nanomaterials For Photonic Applications

    Science.gov (United States)

    2014-08-28

    Y. Han , M. S. Zhao, G. Morthier, and R. Baets. Athermal silicon-on-insulator ring resonators by overlaying a polymer cladding on narrowed waveguides...integrated photonics. Advanced Materials, 22(23):2561, 2010. [152] T. Sondergaard, S. M. Novikov, T. Holmgaard, R. L. Eriksen, J. Beermann, Z. H. Han , K...726, 2011. [181] N. N. Feng, D. Z. Feng, S. R. Liao, X. Wang, P. Dong, H. Liang, C. C. Kung , W. Qian, J. Fong, R. Shafiiha, Y. Luo, J. Cunningham, A. V

  12. Prediction of Communication Outage Period between Satellite and Earth station Due to Sun Interference

    Directory of Open Access Journals (Sweden)

    Yongjun Song

    2010-03-01

    Full Text Available We developed a computer program to predict solar interference period. To calculate Sun‘s position, we used DE406 ephemerides and Earth ellipsoid model. The Sun‘s position error is smaller than 10arcsec. For the verification of the calculation, we used TU media ground station on Seongsu-dong, and MBSAT geostationary communication satellite. We analysis errors, due to satellite perturbation and antenna align. The time error due to antenna align has -35 to +16 seconds at 0.1 degree, and -27 to +41 seconds at 0.25 degree. The time errors derived by satellite perturbation has 30 to 60 seconds.

  13. Iron(II) tetrakis(diaquaplatinum)octacarboxyphthalocyanine supported on multi-walled carbon nanotube platform: an efficient functional material for enhancing electron transfer kinetics and electrocatalytic oxidation of formic acid

    CSIR Research Space (South Africa)

    Mamuru, SA

    2010-10-01

    Full Text Available ]3�/4� 1.0 M KCl solution. (---) Simulated plots and (:) measured plots. Equivalent electrical circuit used for fitting the measured data (d). [Fe(CN)6]4� are equal), R is the ideal gas constant, T is the absolute temperature and F is the Faraday..., X. Qu and S. Dong, Electroanalysis, 2004, 16, 1444. 51 B. W. Dale, Trans. Faraday Soc., 1969, 65, 331. 52 M. J. Stillman and A. J. Thomson, J. Chem. Soc., Faraday Trans.2, 1974, 70, 790. 53 N. Kobayashi, M. Koshiyama, K. Funayama, T. Osa, H...

  14. Generative Audio Design: Emergent Sound Art for an Open World Interface

    OpenAIRE

    Nelson, Blair Robert

    2012-01-01

    Clink. Clank clink. Ink cling clong clang. Cank ling. Ang clang. Clink. Clink. Clink. Clink. Clock clink. Click. Click. Click click. Cling. Clink. Clink clock click. Clah cling clah clink. Clag king. Kink. Dink. Dank. Kank. Ka clang, clonk. Konp. Koh kah cloak clock klink donk. Dong kling. Pah. Klong. Kland. Dah koh. Onk. Donk. Dip. Ing dop. Dop drop drip. Drape kape. Drip. Drip. Drim dram. Dip kip. Rim ram. Hop. Hum. Dim. Kum. Dah dape. Dee. Drip. Drop. Krop din. Dink. Rang drahh. Rimmmm. Ra...

  15. JPRS Report, China, Qiushi (Seeking Truth), No. 7, 1 April 1989.

    Science.gov (United States)

    1989-05-24

    Buddhism and Taoism , we will have only to look at the following process—from the teaching of Six Arts by Confucius, to which Dong Zhongshu added the...impressed by this line of his: "I refused bribes of food and such things, and I can sleep with a clear conscience." It is not easy for a person to...34refuse bribes of food and such things, and sleep with a clear conscience" in today’s society. As I read this line, I think of the person and realize

  16. Eesti Gaas. Inspection of Kohtal-Jaerve - Tallinn pipeline. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    The project `Inspection of Pipelines in Estonia` was funded by Danish government and was carried out in collaboration between DONG, Balslev and FORCE. By agreement between Eesti Gaas and DONG, the pipeline system between Kohtla-Jaerve and Tallinn was selected for inspection. This pipeline system has a total length of 176.9 km. The objective of the project has been, based on detailed inspection of relative short lengths of pipe, to determine the integrity of the pipeline and to give advice concerning the continued use as a high pressure transmission pipeline. The objectives have been met as set out by the project Proposal with the investigation and this report as follows: Based on a document review together with the measurements and observations in the field and in the laboratory, the condition of approximately 5 km of the pipeline has been evaluated; Recommendations are given in this report with the aim of extending the life of the pipeline. A further objective has been to provide know-how transfer in order to permit Eesti Gaas to run similar inspections on other parts of their transmission system. (EG)

  17. Transient and Temporary Overvoltages in the Collection and Export Power Grid in Offshore Wind Power Plants

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Nielsen, Arne Hejde; Holbøll, Joachim

    2009-01-01

    This paper presents an overview of an ongoing Industrial Ph.D. project “Overvoltages and Protection in Offshore Wind Power Grids”, at the Technical University of Denmark (DTU) in cooperation with DONG Energy and Siemens Wind Power. The objective of this project is to improve the understanding and......, reactors and wind farm power transformers, and to develop a methodology on how to select appropriate equipment and protection system.......This paper presents an overview of an ongoing Industrial Ph.D. project “Overvoltages and Protection in Offshore Wind Power Grids”, at the Technical University of Denmark (DTU) in cooperation with DONG Energy and Siemens Wind Power. The objective of this project is to improve the understanding...... and simulation models of the main electrical components in wind farms, based on available information, measurement data and simulation tools. The main aim of this project is to obtain validated models of wind turbine (WT) converters, WT transformers, submarine cables, vacuum circuit breakers, surge arresters...

  18. Visible Light Photocatalytic Properties of Modified Titanium Dioxide Nanoparticles via Aluminium Treatment

    Directory of Open Access Journals (Sweden)

    Dessy Ariyanti

    2016-03-01

    Full Text Available Titanium dioxide (TiO2 has gained much attentions for the last few decades due to its remarkable performance in photocatalysis and some other related properties. However, its wide bandgap (~3.2 eV can only absorb UV energy which is only ~5% of solar light spectrum. The objective of this research was to improve the photocatalytic activity of TiO2 by improving the optical absorption to the visible light range. Here, colored TiO2 nanoparticles range from light to dark grey were prepared via aluminium treatment at the temperatures ranging from 400 to 600 oC. The modified TiO2 is able to absorb up to 50% of visible light (400-700 nm and shows a relatively good photocatalytic activity in organic dye (Rhodamine B degradation under visible light irradiation compared with the commercial TiO2. Copyright © 2016 BCREC GROUP. All rights reserved Received: 10th November 2015; Revised: 7th January 2016; Accepted: 7th January 20 How to Cite: Ariyanti, D., Dong, J.Z., Dong, J.Y., Gao, W. (2016. Visible Light Photocatalytic Properties of Modified Titanium Dioxide Nanoparticles via Aluminium Treatment. Bulletin of Chemical Reaction Engineering & Catalysis, 11 (1: 40-47. (doi:10.9767/bcrec.11.1.414.40-47 Permalink/DOI: http://dx.doi.org/10.9767/bcrec.11.1.414.40-47

  19. Application research for 4D technology in flood forecasting and evaluation

    Science.gov (United States)

    Li, Ziwei; Liu, Yutong; Cao, Hongjie

    1998-08-01

    In order to monitor the region which disaster flood happened frequently in China, satisfy the great need of province governments for high accuracy monitoring and evaluated data for disaster and improve the efficiency for repelling disaster, under the Ninth Five-year National Key Technologies Programme, the method was researched for flood forecasting and evaluation using satellite and aerial remoted sensed image and land monitor data. The effective and practicable flood forecasting and evaluation system was established and DongTing Lake was selected as the test site. Modern Digital photogrammetry, remote sensing and GIS technology was used in this system, the disastrous flood could be forecasted and loss can be evaluated base on '4D' (DEM -- Digital Elevation Model, DOQ -- Digital OrthophotoQuads, DRG -- Digital Raster Graph, DTI -- Digital Thematic Information) disaster background database. The technology of gathering and establishing method for '4D' disaster environment background database, application technology for flood forecasting and evaluation based on '4D' background data and experimental results for DongTing Lake test site were introduced in detail in this paper.

  20. Clinical implication of long noncoding RNA 91H expression profile in osteosarcoma patients

    Directory of Open Access Journals (Sweden)

    Xia WK

    2016-07-01

    Full Text Available Wen-Kai Xia,1 Qing-Feng Lin,2 Dong Shen,2 Zhi-Li Liu,2 Jun Su,2 Wei-Dong Mao2 1Department of Nephrology, 2Department of Oncology, The Affiliated Jiangyin Hospital, School of Medicine, Southeast University, Jiangyin, Jiangsu, People’s Republic of China Abstract: Long noncoding RNAs have been documented as having widespread roles in carcinogenesis and cancer progression. However, roles of long noncoding RNAs in osteosarcoma remain unclear. This study is to investigate the clinical relevance and biological functions of long noncoding RNA 91H in osteosarcoma. Herein, we confirmed that 91H expression was notably increased in osteosarcoma patients and cell lines compared to healthy controls and normal human bone cell lines. High expression of 91H was significantly correlated with advanced clinical stage, chemotherapy after surgery, and tumor size >5 cm. Furthermore, 91H was an independent prognostic factor for overall survival in osteosarcoma patients after treatments. Additionally, the knockdown of 91H expression inhibited osteosarcoma cells’ proliferation and promoted their apoptosis in vitro. In summary, these findings indicate that 91H may be a novel biomarker for risk prognostication and also provide a clue to the molecular etiology of osteosarcoma. Keywords: long noncoding RNA, 91H, osteosarcoma, survival

  1. Review of selected non-seismic methods for onshore hydrocarbon exploration in Denmark. ALTKUL project report part 1

    Energy Technology Data Exchange (ETDEWEB)

    Rasmussen, T.M.; Thorning, L.

    2012-09-15

    Project ALTKUL was commissioned by DONG E and P A/S and Nordsoefonden; the Danish Energy Agency followed the project closely. The starting point of the study was the need in Danish onshore areas for more knowledge on alternative methods that could be used for hydrocarbon exploration, as an alternative to seismic investigations. DONG E and P A/S and Nordsoefonden approached GEUS, suggesting a study of seven different methods. The Danish Energy Agency was interested in the subject and requested that an actual test of a method be carried out as a part of the project. The seven methods considered and reviewed are: 1: Surface geochemistry; 2: Gravimetric modelling; 3: Magnetotellurics (MT, AMT and ZTEM); 4: High-Moment Electromagnetics (HMEM); 5: High-Powered Spectral Induced Polarization (HPSIP); 6: Electron Para-magnetic Resonance (EPR); 7: Airborne Transient Pulse Surveys. Getting a test of one of the methods based on electromagnetic theory organised caused some difficulties. An experiment with a galvanic controlled source was considered to be the optimum choice. However, based on various contacts and failed attempts to organise a test, a contract was entered with Uppsala University for some initial tests of the MT method. The test is to be carried out in August 2012 and will be reported in a separate report (ALTKUL Project Report Part 2). (LN)

  2. DNV RP-F116 integrity management of submarine pipeline system

    Energy Technology Data Exchange (ETDEWEB)

    Leinum, B.H.; Etterdal, B. [Det Norske Veritas (DNV), Hoevik (Norway); Augustinovic, Z. [Dong Energy, Fredericia (Denmark); Paula, A. [Det Norske Veritas (DNV), Rio de Janeiro, RJ (Brazil)

    2009-12-19

    The need to keep pipelines operating safely and efficiently is paramount for any operator. Additionally, there is an increasing awareness at both regulatory and public level. Authorities around the world are adopting a more proactive approach as they seek to minimize the risk of human injuries or harm to the environment resulting from pipeline leaks. A joint industry project (JIP) led by DNV Energy is formulating guidelines for how to manage the integrity of submarine pipeline system. The resultant document of recommended practice, DNV RP-F116, will provide the oil and gas industry with a useful tool in an area where no such formal guidance currently exists. This paper gives an overview of the RP and demonstrates the use with a case study for the Siri field. The Siri field is operated by DONG Energy, Denmark and all infield pipelines were subjected to an integrity assessment using the Integrity Management process as outlined in the upcoming DNV RP-116. In parallel with establishing the RP, DNV has further developed the web-based software system, Orbit+, which is aligned with the RP. The software system is implemented and used by Dong Energy. (author)

  3. An analysis of the combination frequencies of constituent medicinal herbs in prescriptions for the treatment of bone and joint disorder in Korean medicine: determination of a group of candidate prescriptions for universal use

    Directory of Open Access Journals (Sweden)

    Yoo Kyoung Han

    2017-12-01

    Full Text Available Background: This study aimed to select prescriptions (mixtures of medicinal herbs used in the treatment of bone and joint disorders in Korean medicine, and through the analysis of medicinal herb combination frequencies, select a high-frequency medicinal herb combination group for further experimental and clinical research. Methods: We systematically searched for terms related to bone and joint disorder in the “Dongeuibogam (Dong yibaojian”, a seminal Korean medicine book. We reviewed the results of published papers regarding the effects in bone and joint disorders (especially in osteoporosis, osteomalacia, osteopenia, rheumatoid arthritis, and degenerative arthritis. Results: In total, 34 candidates of a medicinal herb combination for the treatment of bone and joint disorders(CMHCTBJDs and nine candidates of a medicinal herb for the treatment of bone and joint disorders(CMHTBJDs were selected. Conclusion: : The candidates of a medicinal herb combination for the treatment of bone and joint disorders (CMHCTBJDs and candidates of a medicinal herb for the treatment of bone and joint disorders(CMHTBJDs proposed in this study can be useful material for text mining to develop natural products with the effects in BJDs and also it has the potential to reduce the experimental and developmental time period. Keywords: Dongeuibogam (Dong yi bao gian, Text mining, Bone disorder

  4. Lithuania training needs analysis

    International Nuclear Information System (INIS)

    1993-12-01

    The present assessment of training needs in the Lithuanian natural gas sector is one of a total of four programmes on which Danish Oil and Natural Gas (DONG) and Lithuanian Gas (LG) cooperate. DONG's contribution is financed by the Danish Foreign Ministry. Long-term Objective is enhancement of the natural gas sector in Lithuania for efficient, cost-effective and environmentally responsible energy supply and utilization, in accordance with international standards. Immediate Objective is to establish a basis of competence in the Lithuanian Gas Sector, manage the modernization process effectively, and develop the involved human resources to the required performance level. The strategy for training in the Lithuanian natural gas sector proposed by this report integrates recommendations under three main headings: Six programmes of training and development. Strengthening of the institutional framework and the system for training. Upgrading of training capacity. The six programmes comprise: Legislation and Educational Planning. Management Development. Economy. Marketing and Sales. Supervisory Skills Development. Training Skills Development. Management and Specialists' Workshops on Technology. Following organisation for implementation of recommendations is proposed: Steering Board. Advisory Board. Coordination Group. Project Management Group. Group of Lithuanian Specialists. Group of Advisers. Short-term Consultants/Teachers. Lithuanian Consultants/Teachers. The project is envisaged to be implemented in carefully timed phases allowing for coordination between management workshops, training programmes and revision work regarding the institutional framework for training and the training system. (EG)

  5. Kombinasi Firefly Algorithm-Tabu Search untuk Penyelesaian Traveling Salesman Problem

    Directory of Open Access Journals (Sweden)

    Riyan Naufal Hay's

    2017-07-01

    Full Text Available Traveling Salesman Problem (TSP adalah masalah optimasi kombinatorial klasik dan memiliki peran dalam perencanaan, penjadwalan, dan pencarian pada bidang rekayasa dan pengetahuan (Dong, 2012. TSP juga merupakan objek yang baik untuk menguji kinerja metode optimasi, beberapa metode seperti Cooperative Genetic Ant System (CGAS (Dong, 2012, Parallelized Genetic Ant Colony System (PGAS Particle Swarm Optimization and Ant Colony Optimization Algorithms (PSO–ACO (Elloumi, 2014, dan Ant Colony Hyper-Heuristics (ACO HH (Aziz, 2015 telah dikembangkan untuk memecahkan TSP. Sehingga, pada penelitian ini diimplementasikan kombinasi metode baru untuk meningkatkan akurasi penyelesaian TSP. Firefly Algorithm (FA merupakan salah satu algoritma yang dapat digunakan untuk memecahkan masalah optimasi kombinatorial (Layeb, 2014. FA merupakan algoritma yang berpotensi kuat dalam memecahkan kasus optimasi dibanding algoritma yang ada termasuk Particle Swarm Optimization (Yang, 2010. Namun, FA memiliki kekurangan dalam memecahkan masalah optimasi dengan skala besar (Baykasoğlu dan Ozsoy, 2014. Tabu Search (TS merupakan metode optimasi yang terbukti efektif untuk memecahkan masalah optimasi dengan skala besar (Pedro, 2013. Pada penelitian ini, TS akan diterapkan pada FA (FATS untuk memecahkan kasus TSP. Hasil FATS akan dibandingkan terhadap penelitian sebelumnya yaitu ACOHH. Perbandingan hasil menunjukan peningkatan akurasi sebesar 0.89% pada dataset Oliver30, 0.14% dataset Eil51, 3.81% dataset Eil76 dan 1.27% dataset KroA100.

  6. Mutations induced by gamma irradiation in rice breeding for salt tolerance

    International Nuclear Information System (INIS)

    Nguyen Thi Lang; Bui Minh Tam; Bui Chi Buu

    2011-01-01

    New breeding lines were developed through mutagenesis of known varieties using radiation. Development of 10 local varieties from the Vietnamese traditional variety . Seeds of 10 varieties were gamma-irradiated and the generated plantlets were advanced to M 2 and screened for salinity tolerance at seedling stage during both M 2 and M 5 generations. Putative salt tolerant mutants were identified and further advanced and evaluated for agronomic and adaptive traits. The experiment comprised of 12 lines were laid out in a randomized block design replicated three times at 8 different locations at Dong Xuan season from Mekong delta . Analysis of variance indicated the presence of significant genetic variability among the genotypes for grain yield under all the five location . All analyses of variance for yield that were pooled over the five locations. Genotypes x Environment (G x E) interactions were also found significant and the mean squares due to environment were highly significant indicating sufficient diversity among the environments. Three lines OM 5928(db), AS996(db3), As996(db1). Among the lines, AS996(DB1) performed better by yielding highly in all the locations both stability at Dong Xuan and HeThu seasons. This varieties is good for multiplication in the future. (author)

  7. Evaluating physical and perceptual responses to exergames in Chinese children.

    Science.gov (United States)

    Lau, Patrick W C; Liang, Yan; Lau, Erica Y; Choi, Choung-Rak; Kim, Chang-Gyun; Shin, Myung-Soo

    2015-04-13

    The primary objective of this study was to examine whether exergames could help children reach the recommendations for PA and cardiorespiratory fitness regarding exercise intensity. Differences in perceived physical exertion, EE, VO2, and HR between normal weight (NW) and overweight (OW) children participating in exergames were also examined. Twenty-one children (age: 10.45 ± 0.88) were assessed for EE, VO2 and HR during rest, in a maximal treadmill test, and while playing different exergames. Ratings of perceived exertion (RPE) (category range: 0 to 10) were also measured during exergaming. Three types of exergames were examined: running, table tennis, and dancing. These games were either performed on a Chinese game console, I-Dong, or another well-developed Western game console (Sony PlayStation 3 or Nintendo Wii). Exergaming resulted in EE (kcal/min) from 2.05-5.14, VO2 (mL/kg/min) from 9.98-25.54, and HR (beats per minute) from 98.05-149.66. Children reported RPE ranging from 1.29 to 5.29. The Chinese exergame, I-Dong Running, was the only game in which children reached a moderate intensity and met the recommended minimum VO2reserve (50%) for cardiorespiratory fitness. Exergames could provide alternative opportunities to enhance children's physical activity. They could be used as light-to-moderate PA, and with exergames, children can even reach the recommended intensity for developing and maintaining cardiorespiratory fitness.

  8. Osthole: A Review on Its Bioactivities, Pharmacological Properties, and Potential as Alternative Medicine

    Directory of Open Access Journals (Sweden)

    Zhong-Rong Zhang

    2015-01-01

    Full Text Available This paper reviews the latest understanding of biological and pharmacological properties of osthole (7-methoxy-8-(3-methyl-2-butenyl-2H-1-benzopyran-2-one, a natural product found in several medicinal plants such as Cnidium monnieri and Angelica pubescens. In vitro and in vivo experimental results have revealed that osthole demonstrates multiple pharmacological actions including neuroprotective, osteogenic, immunomodulatory, anticancer, hepatoprotective, cardiovascular protective, and antimicrobial activities. In addition, pharmacokinetic studies showed osthole uptake and utilization are fast and efficient in body. Moreover, the mechanisms of multiple pharmacological activities of osthole are very likely related to the modulatory effect on cyclic adenosine monophosphate (cAMP and cyclic adenosine monophosphate (cGMP level, though some mechanisms remain unclear. This review aims to summarize the pharmacological properties of osthole and give an overview of the underlying mechanisms, which showcase its potential as a multitarget alternative medicine.

  9. Potential candidates for biological control of the black bean aphid Aphis fabae in Serbia

    Directory of Open Access Journals (Sweden)

    Stanković, S.S.

    2015-09-01

    Full Text Available The black bean aphid is widely spread aphid species in the Palaearctic, known to attack over 1150 plant species. Because some of the host plants are of great agricultural interest, Aphis fabae represent a very important pest. We assembled all data concerning the presence of this pest and connected it in tritrophic associations. In the period of 24 years investigation on the territory of Serbia it has been recorded in 107 trophic associations. In total there are 145 findings of A. fabae parasitized by 19 taxa of Aphidiinae (Brackonidae from seven genera. The most suitable biocontrol agents for the black bean aphid are Lysiphlebus fabarum, Binodoxys angelicae, Lipolesis gracilis and the introduced species Lysiphlebus testaceipes.

  10. The Effect of Z-Ligustilide on the Mobility of Human Glioblastoma T98G Cells.

    Directory of Open Access Journals (Sweden)

    Jun Yin

    Full Text Available Z-ligustilide (LIG, an essential oil extract from Radix Angelica sinensis, has broad pharmaceutical applications in treating cardio-vascular diseases and ischemic brain injury. Recently, LIG has been connected to Glioblastoma multiforme (GBM because of its structural similarity to 3-n-alkyphthalide (NBP, which is specifically cytotoxic to GBM cells. Hence, we investigated LIG's effect on GBM T98G cells. The study shows that LIG can significantly reduce T98G cells' migration in a dose-dependent manner. Furthermore, the attenuation of cellular mobility can be linked to the activity of the Rho GTPases (RhoA, Rac1 and Cdc42, the three critical molecular switches governing cytoskeleton remodeling; thus, regulating cell migration. LIG significantly reduces the expression of RhoA and affects in a milder manner the expression of Cdc42 and Rac1.

  11. Electronic Nose Odor Classification with Advanced Decision Tree Structures

    Directory of Open Access Journals (Sweden)

    S. Guney

    2013-09-01

    Full Text Available Electronic nose (e-nose is an electronic device which can measure chemical compounds in air and consequently classify different odors. In this paper, an e-nose device consisting of 8 different gas sensors was designed and constructed. Using this device, 104 different experiments involving 11 different odor classes (moth, angelica root, rose, mint, polis, lemon, rotten egg, egg, garlic, grass, and acetone were performed. The main contribution of this paper is the finding that using the chemical domain knowledge it is possible to train an accurate odor classification system. The domain knowledge about chemical compounds is represented by a decision tree whose nodes are composed of classifiers such as Support Vector Machines and k-Nearest Neighbor. The overall accuracy achieved with the proposed algorithm and the constructed e-nose device was 97.18 %. Training and testing data sets used in this paper are published online.

  12. Herbal Extract SH003 Suppresses Tumor Growth and Metastasis of MDA-MB-231 Breast Cancer Cells by Inhibiting STAT3-IL-6 Signaling

    Directory of Open Access Journals (Sweden)

    Youn Kyung Choi

    2014-01-01

    Full Text Available Cancer inflammation promotes cancer progression, resulting in a high risk of cancer. Here, we demonstrate that our new herbal extract, SH003, suppresses both tumor growth and metastasis of MDA-MB-231 breast cancer cells via inhibiting STAT3-IL-6 signaling path. Our new herbal formula, SH003, mixed extract from Astragalus membranaceus, Angelica gigas, and Trichosanthes kirilowii Maximowicz, suppressed MDA-MB-231 tumor growth and lung metastasis in vivo and reduced the viability and metastatic abilities of MDA-MB-231 cells in vitro. Furthermore, SH003 inhibited STAT3 activation, which resulted in a reduction of IL-6 production. Therefore, we conclude that SH003 suppresses highly metastatic breast cancer growth and metastasis by inhibiting STAT3-IL-6 signaling path.

  13. Anti-inflammatory and neuroprotective effect of a phytoestrogen compound on rat microglia.

    Science.gov (United States)

    Marotta, F; Mao, G S; Liu, T; Chui, D H; Lorenzetti, A; Xiao, Y; Marandola, P

    2006-11-01

    Ovariectomized Wistar rats received orally 15 mg/kg of a phytoestrogen compound (genistein, daidzein, glycitein, black cohosh, angelica sin., licorice, vitex agnus) for 2 weeks to test its ability to modulate inflammatory microglia response. Microglial proliferation was tested by trypan blue and by absorbance. Serial supernatant sampling was performed for 24 h to check TNF-alpha, IL-beta, IL-6, and TGF-beta. LPS caused a time course increase of all cytokines, with IL-beta and TNF-alpha peaking at the 12th hour, whereas IL-6 and TGF-beta peaked at the 24 h observation. Rats fed with the phytoestrogen displayed a significantly lower level of proinflammatory cytokines and a higher level of TGF-beta, as shown also by Western blot analysis. This finding may offer promise in the field of nutraceutical intervention.

  14. Effect of Zi Gui decoction on immune function in {sup 60}Co {gamma}-ray irradiated mice

    Energy Technology Data Exchange (ETDEWEB)

    Qiujun, Lu; Shafei, Huang; Xipeng, Zhou; Jiayun, Song; Zhongxiong, Tang [Dept. of Pharmacology, Institute of Radiation Medicine, Beijing (China)

    1995-02-01

    Zi Gui decoction (ZG), a complex preparation of traditional Chinese herbal medicine, mainly consists of Radix Angelicae and Radix Astragali. The effects of ZG on mitogen induced proliferation IL-1 and -2 production, natural killer (NK) cell activity in {sup 60}Co {gamma}-ray irradiated mice is investigated. After 5 Gy whole body irradiation. mice were treated i.g. with ZG (1.2, 1.8 g/kg/day) for 20 days. An enhancement in Con A- and LPS-induced proliferations of splenocytes from the two dosage groups were observed. There were marked increases in IL-1 activity in peritoneal macrophage culturesa and IL-2 activity in splenocyte cultures from irradiated mice treated with ZG. The two dosage groups also showed significant potentiation of NK cell activity against YAC-1 target cells. The above results indicated that ZG could promote the recovery of immune functions in {gamma}-ray irradiated mice.

  15. The Clinical and Experimental Studies of ChanLe Chongji for Reducing Bleeding after Abortion

    Institute of Scientific and Technical Information of China (English)

    赵荣胜; 丁元珍; 胡燕尔

    1999-01-01

    ChanLe Chongji (ChanLe dissolvable granule preparation) is a mixed Chinese traditional medicine composed of Prunus persica Batsch, Carthamus tinctorius, Angelica sinensis Diets, Typha angustifotia Borv. et Chaub. , Prunus mume Sieb. et Zucc.,etc. which could clear fever and remove blood stasis. The bleeding days in vagina after abortion by drug and the complete abortion rate were observed, 100cases were selected randomly from the treated group and the control group respectively. The results showed that the mean bleeding period in the treated group was 8. 4 days, while 13.3 days in the control. Although the mean complete abortion rate had no distinct difference between these two groups, the absolute level was higher in the treated group. The resuits of animal experiments showed that ChanLe Chongji could increase the contraction of uterus, stop bleeding, resist bacteria and diminish inflammation, thus providing its potentiality for clinical application.

  16. Biochemical and molecular genetic approaches on the radioprotective mechanism of natural products

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jeong Hee; Lee, Eun Ju; Sung, Woo Kyung; Piao, Wen Hua [Kyunghee University, Seoul (Korea)

    1999-04-01

    We reported the radio-protective effect of DTT. The treatment of DTT increased cell survival after gamma-irradiation, decreased in the frequencies of micronucleus, and reduction in DNA fragmentation and apoptotic cells. Induction of apoptosis after UV-C irradiation was revealed by the changes in the relative cell death, increase in the relative amount of apoptotic cells, and the induction of DNA fragmentation. About 100 medicinal plants were purchased and methanol extract samples were prepared. Radio-protective and radio-sensitizing activities of these samples were screened. Seven samples showed above 20% radio-protective activities: Salvia miltiorrhiza, Areca catechu, Cornus officinalis, Alpiniae officinari rhizoma, Meliae fructus, Alpiniae katsumadaii semen, Betulae cortex. Acanthopanax sessiliflous showed the highest radio-sensitizing effect and 10 other samples revealed moderate activities: Melia japonica, Agastache rugosa, Platycodon gradiflorum, Broussonetia bazinoki, Angelica gigas, Inula helenium, Chelidonium majus, Pulsatilla koreana, Oldenlandia diffusa, Dioscorea batatas. (author). 49 refs., 9 figs., 7 tabs.

  17. Decursin was Accelerated Human Lung Cancer Cell Death Caused by Proton Beam Irradiation via Blocking the p42/44 MAPK pathway

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Myung Hwan; Ra, Se Jin; Kim, Kye Ryung [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2011-10-15

    Decursin, which is one of the extract of Angelica gigas Nakai root, has been traditionally used in Korean folk medicine as a tonic and for treatment of anemia and other common diseases. There are some reports about the pharmacological properties of decursin showing anti-bacterial and anti-amnestic effect, depression of cardiac contraction, antitumor and anti-angiogenic activity. Cell death induced by proton beam is identified as apoptosis. The study investigated that genes involved in apoptosis are checked by RT-PCR and used LET instead of SPBP of proton beam. Apoptosis is the tight regulated by multi-protein action in physiological cell death program. Proton therapy is an attractive approach for the treatment of deep-seated tumor. Recently, many researchers tried to new therapeutic strategy, combination of proton therapy and chemotherapy, in order to increase therapeutic effect. In this study, we investigate whether decursin can accelerate effect of human lung cell apoptosis in proton irradiated cancer cells

  18. Descrevendo a prática clínica junguiana no Brasil: quem somos, o que pensamos e o que fazemos nós, afinal?

    OpenAIRE

    Caetano, Aurea Afonso M.

    2016-01-01

    Este estudo teve como objetivo fazer uma pesquisa para verificar quem são, como trabalham e o que pensam, os terapeutas de abordagem junguiana brasileiros, acerca de sua prática clínica. Pretendemos verificar onde trabalham, com quem trabalham e como trabalham os terapeutas de abordagem junguiana; quais são os fundamentos teóricos mais importantes para seu atendimento clínico, quais as técnicas terapêuticas específicas que utilizam nesse trabalho e qual o sentido para o tera...

  19. Transparência e Replicabilidade na Pesquisa Empírica em Direito: conceitos e ferramentas

    OpenAIRE

    Oliveira, Paulo

    2018-01-01

    Com o crescimento das pesquisas empíricas em Direito quais as práticas devem ser adotadas pelos pesquisadores para acompanhar o Padrão Ouro da pesquisa? Quais os conceitos necessários para que a Pesquisa Empírica possa crescer de forma sustentável e democrática? Esse artigo tenta delinear alguns conceitos importantes da Ciência 2.0 e mostra algumas das principais ferramentas para atingir plenamente o ideal de Ciência Aberta.

  20. Nativos digitais versus imigrantes digitais: análise interpretativista das diferenças no uso das TIC em seu cotidiano e sua percepção do ensino na atualidade

    OpenAIRE

    Prado, Clara Vianna

    2015-01-01

    O presente trabalho visa discutir mudanças acerca do uso das tecnologias de informação e comunicação (TIC) entre dois grupos de participantes: os nativos digitais e a dos imigrantes digitais. Visa assim, (1) identificar quais as mídias que têm sido utilizadas nesses dois contextos e quais as diferenças identificadas nos dois grupos de participantes; (2) identificar como os diferentes grupos de participantes utilizam os instrumentos disponíveis nas tecnologias digitais; e, por f...

  1. Aplicação de um sistema de classificação de carcaças e cortes e efeito pós abate da qualidade de cortes de frango criados no sistema alternativo.

    OpenAIRE

    Mónica Beatriz Alvarado Huallanco

    2005-01-01

    A qualidade da carne envolve aspectos estéticos, avaliados pelo consumidor e físico-químicos importantes para o processador, os quais podem ser controlados nas diversas etapas de produção. Na primeira fase, a fim de determinar a qualidade de carcaças e cortes aplicou-se um sistema de classificação, os quais foram avaliados na aparência (conformação, conteúdo de carne, cobertura de gordura, depenagem, carne exposta e corte, ossos quebrados, descolorações e hematomas) e classificados em níveis ...

  2. Aplicação de processos oxidativos avançados no tratamento de águas contaminadas com efluentes têxteis

    OpenAIRE

    Rodrigues, Suely da Silva

    2014-01-01

    Nas últimas décadas, o fenômeno da contaminação ambiental alcançou proporções globais. Dentro deste contexto, a atividade industrial costuma apresentar um papel de destaque, principalmente em razão da geração de uma vasta quantidade de resíduos, os quais, quando não adequadamente tratados, apresentam um elevado potencial poluente. Neste contexto é possível destacar as indústrias têxteis, as quais se caracterizam pelo elevado consumo de água e pela geração de grandes volumes ...

  3. Caracterização sensorial por analise descritiva quantitativa e analise tempo-intensidade de suco e de polpa de manga (Mangifera indica L.) adoçados com diferentes edulcorantes.

    OpenAIRE

    Daniela Cardoso Umbelino

    2005-01-01

    Resumo: O Brasil possui um grande potencial de produção de sucos de frutas tropicais, entre os quais destaca-se o suco de manga. Por outro lado, a preocupação com a saúde impulsionou a pesquisa e o desenvolvimento de alimentos de baixa caloria e adoçantes não calóricos. Os edulcorantes podem produzir características sensoriais indesejáveis, sendo necessário estudá-los, individualmente, no alimento ou bebida aos quais são adicionados. Este trabalho teve por objetivo estudar o comportamento do ...

  4. A visão das crianças sobre o lazer

    OpenAIRE

    Rocha, Michelle Araújo; de Souza, Luciana Karine

    2012-01-01

    RESUMO: Este estudo buscou conhecer o conceito de lazer de crianças, suas práticas de lazer, a companhia nessas práticas, se se aprende algo com o lazer, quais atividades fariam mais e quais deixariam de fazer. Foram entrevistadas individualmente 41 crianças de 9 a 10 anos de idade, estudantes de escolas públicas ou privadas da cidade de Belo Horizonte. As respostas transcritas passaram por análise de conteúdo, gerando categorias de unidades temáticas semelhantes. O lazer para estas crianças ...

  5. Rodas de ciências na educação infantil: um aprendizado lúdico e prazeroso

    OpenAIRE

    Celi Rodrigues Chaves Dominguez

    2001-01-01

    Esta investigação teve o objetivo de identificar as características de ludicidade presentes em rodas de conversa sobre assuntos científicos às quais chamamos de rodas de ciências , realizadas em um grupo de crianças de quatro anos, em uma escola de educação infantil. As rodas de ciências nas quais as crianças conversavam sobre borboletas foram gravadas em áudio e vídeo, no decorrer de aproximadamente seis meses. Constatamos que as rodas apresentavam características lúdicas apenas quando as...

  6. The Road to El Dorado: China discovers Africa

    Directory of Open Access Journals (Sweden)

    Paulo Duarte

    2012-06-01

    Este artigo analisa as várias dimensões, oportunidades e desafios da presença chinesa em África, procurando demonstrar que a estratégia africana da China é uma estratégia multidimensional, composta por vários fatores (económicos, políticos, militares – nos quais o soft e o hard power também estão incluídos, os quais contribuem para um todo harmonioso, sublinhando a importância de África para a China e vice-versa.

  7. Hanseníase: um estudo sobre a experiência da enfermidade de pacientes em Salvador-Bahia

    OpenAIRE

    Martins, Patrícia Vieira

    2013-01-01

    A pesquisa que originou esta tese foi realizada com indivíduos residentes no Estado da Bahia, que buscaram tratamento em um hospital de referência na cidade de Salvador, e teve como objetivo responder, a partir de uma perspectiva socioantropológica, a uma série de indagações, tais como: de que maneira os pacientes construíram a experiência da enfermidade vivenciada por eles; qual foi a repercussão social da doença em suas vidas; quais os significados atribuídos a ela; quais as estratégias de ...

  8. Modelos experimentais de desnutrição e sua influência no trofismo cutâneo

    OpenAIRE

    Leite,Saulo Nani; Jordão Júnior,Alceu Afonso; Andrade,Thiago Antônio Moretti de; Masson,Daniela dos Santos; Frade,Marco Andrey Cipriani

    2011-01-01

    FUNDAMENTOS: A pele, para exercer suas funções, necessita de níveis adequados de nutrientes. OBJETIVO: Analisar o trofismo cutâneo de ratos nutridos e desnutridos por meio de dois modelos de desnutrição. MÉTODOS: No Modelo Marasmo, utilizaram-se 60 ratos Wistar em controle dietético, dos quais 30 foram selecionados aleatoriamente para receber metade da dieta diária durante 60 dias. No Modelo Gelatina, empregaram-se 60 ratos, dos quais 30 receberam dieta associada a proteína de baixa qualidade...

  9. : Posturas de apreensão sensível da cidade contemporânea

    OpenAIRE

    Thomas , Rachel

    2012-01-01

    International audience; Como apreender a cidade contemporânea? Quais metodologias utilizar? Em qual filiação teórica e segundo quais noções conceituais ancorar esta apreensão? O tema é ambicioso. Ele também é bastante vasto, muito complexo e oferece de fato múltiplas pistas de reflexão. Eu escolherei três que não são nem dogmas, nem uma metodologia a se seguir às cegas, mas sobretudo caminhos de pensamento a compartilhar. O primeiro diz respeito a necessidade hoje de construir e de desenvolve...

  10. Work family balance : mito ou aptidão : estudo empírico sobre antecedentes e consequências

    OpenAIRE

    Pedro, Ana Margarida Alexandre

    2016-01-01

    Dissertação de mestrado em Marketing, apresentada à Faculdade de Economia da Universidade de Coimbra, sob a orientação de Arnaldo Fernandes Matos Coelho e Joaquim Luís Medeiros Alcoforado. “Work Family Balance – Mito ou Aptidão? Estudo Empírico Sobre Antecedentes e Consequências” visa contribuir, com base na revisão bibliográfica, para a compreensão de quais as variáveis que contribuem para esse equilíbrio dinâmico e quais as repercussões. Este tema insere-se no Marketing Inter...

  11. Oswald De Andrade Em Torno De 1922: Descompassos Entre Teoria E Expressão Estética

    OpenAIRE

    Gênese Andrade

    2015-01-01

    Este ensaio aborda textos de Oswald de Andrade anteriores à Semana de Arte Moderna, nos quais ele antecipa ideias que constituirão sua produção estética no modernismo, e artigos em que ele trata da Semana de 22. Focaliza ainda o descompasso entre as ideias apresentadas nos artigos e sua própria obra literária anterior à Semana de Arte Moderna, e ainda entre a literatura e as artes plásticas, nas quais o modernismo se concretizou mais precocemente.

  12. Projetos: deliberados ou emergentes. as práticas em gerenciamento de projetos e a estratégia empresarial

    OpenAIRE

    Lopes, Raphael de Oliveira Albergarias

    2010-01-01

    A pergunta "O Gerenciamento de Projetos é necessário?" Raramente é questionada nos dias de hoje. As questões mais relevantes são: Quais são as melhores práticas, ferramentas, e competências para que o Gerenciamento de Projetos seja conduzido de forma profissional? Quais são os componentes que constituem qualidade no Gerenciamento de Projetos? O que é sucesso no Gerenciamento de Projetos? A grande importância da Estratégia Empresarial para a definição da posição de uma com...

  13. Fresnel: O formulador matemático da teoria ondulatória da luz

    OpenAIRE

    Bassalo, José Maria Filardo

    1988-01-01

    Neste artigo, apresentamos alguns aspectos da vida de Fresnel, engenheiro e físico francês que se notabilizou pela formulação matemática da teoria ondulatória da luz, e cujo bicentenário de nascimento transcorre neste ano de 1988. Realçamos, neste trabalho, suas principais pesquisas relacionadas com o estudo da difração, dupla-refração e reflexão da luz, nas quais utilizou a idéia revolucionária de transversalidade da onda luminosa para deduzir equações, as quais explicaram alg...

  14. A defensoria pública e o acesso coletivo à justiça

    OpenAIRE

    Amanda Marques Batista

    2008-01-01

    O presente estudo destinou-se à compreensão do conceito de acesso coletivo à justiça, a partir da verificação do que é, como ocorre, quais os mecanismos existentes no sistema processual vigente que propiciam o acesso à justiça dos grupos sociais necessitados, bem como a legitimidade da Defensoria Pública para a defesa dos interesses difusos, coletivos e individuais homogêneos. Em virtude do crescente número de conflitos coletivos existentes atualmente, os quais giram em torno dos direitos do ...

  15. Pensamento estratégico nas organizações

    OpenAIRE

    Kich, Juliane Ines Di Francesco

    2015-01-01

    Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico, Programa de Pós-Graduação em Administração, Florianópolis, 2015. A presente tese propõe um modelo que subsidia o desenvolvimento do pensamento estratégico nas organizações. Tem como objetivo maior responder a seguinte pergunta de pesquisa: Quais são os atributos que formam o conceito do pensamento estratégico, e quais são os elementos organizacionais que desenvolvem tais atributos nos membros de uma organiza...

  16. International political relations: how to understand them?

    OpenAIRE

    Mallmann, Maria Izabel

    2006-01-01

    Objetiva-se discutir neste artigo as teorias das relações internacionais. Para tanto, percorre-se a questão das teorias fundadoras: idealismo-liberalismo e realismo, explicando-as em seus fundamentos e apresentando as raízes das teorias políticas nas quais se baseiam, nas quais sempre bebem os pensadores além de levarem a desdobramentos práticos na diplomacia e política internacional. Falar de idealismo-liberalismo e realismo em política internacional tem conseqüências mais amplas que a simpl...

  17. Complementary and alternative interventions in asthma, allergy, and immunology.

    Science.gov (United States)

    Bielory, Leonard

    2004-08-01

    To review which herbs are most commonly used as complementary and alternative medicine (CAM) for treatment of asthma, allergy, and immunologic conditions. A review of the literature was performed using the PubMed and OVID databases searching the keywords asthma, allergy, and CAM to identify studies published between 1980 and 2003 that focused on Echinacea (Echinacea augustifolia, Echinacea pallida, and Echinacea purpurea); garlic (Allium); angelica; chamomile; ephedra; gingko; grape seed extract; licorice root (Glycyrrhiza); St. John's wort (Hypericum); kava kava (Piper); peppermint oil and leaf (Mentha); stinging nettle (Urtica); and ginseng (Panax) published in the English and German literature. Studies included in vitro and in vivo clinical trials and case reports selected according to the expert opinion of the author. Echinacea is one of the most common herbs used to treat symptoms of the "common cold" or upper respiratory tract allergies. Although no common drug interactions have been reported, there is a risk of hepatotoxicity, exacerbation of allergies and asthma, and anaphylactic reactions. Garlic is primarily used for cardiovascular health and relief of cough, colds, and rhinitis. Adverse effects commonly include gastrointestinal disturbances, change in body odor through the sweat and breath, and rarely allergic reactions or hypoglycemia. Other CAM agents, including angelica, German chamomile flower, ephedra, gingko, grape seed extract, licorice root, St. John's wort, kava kava rhizome, peppermint, stinging nettle, and ginseng, are also associated with significant adverse effects. The specialty of allergy and immunology has seen the second largest increase in the popularity of CAM (second only to practitioners who treat lower back pain). Almost all of the CAM interventions have displayed adverse effects, usually in the form of a hypersensitivity reaction. Allergists and clinical immunologists need to become more knowledgeable about CAM so that they can

  18. Botanical Provenance of Traditional Medicines From Carpathian Mountains at the Ukrainian-Polish Border.

    Science.gov (United States)

    Kozlowska, Weronika; Wagner, Charles; Moore, Erin M; Matkowski, Adam; Komarnytsky, Slavko

    2018-01-01

    Plants were an essential part of foraging for food and health, and for centuries remained the only medicines available to people from the remote mountain regions. Their correct botanical provenance is an essential basis for understanding the ethnic cultures, as well as for chemical identification of the novel bioactive molecules with therapeutic effects. This work describes the use of herbal medicines in the Beskid mountain ranges located south of Krakow and Lviv, two influential medieval centers of apothecary tradition in the region. Local botanical remedies shared by Boyko, Lemko, and Gorale ethnic groups were a part of the medieval European system of medicine, used according to their Dioscoridean and Galenic qualities. Within the context of ethnic plant medicine and botanical classification, this review identified strong preferences for local use of St John's-wort ( Hypericum perforatum L.), wormwood ( Artemisia absinthium L.), garlic ( Allium sativum L.), gentian ( Gentiana lutea L.), lovage ( Levisticum officinale W.D.J. Koch), and lesser periwinkle ( Vinca minor L.). While Ukrainian ethnic groups favored the use of guilder-rose ( Viburnum opulus L.) and yarrow ( Achillea millefolium L.), Polish inhabitants especially valued angelica ( Angelica archangelica L.) and carline thistle ( Carlina acaulis L.). The region also holds a strong potential for collection, cultivation, and manufacture of medicinal plants and plant-based natural specialty ingredients for the food, health and cosmetic industries, in part due to high degree of biodiversity and ecological preservation. Many of these products, including whole food nutritional supplements, will soon complement conventional medicines in prevention and treatment of diseases, while adding value to agriculture and local economies.

  19. Comparative Analysis of Compatibility Effects on Invigorating Blood Circulation for Cyperi Rhizoma Series of Herb Pairs Using Untargeted Metabolomics

    Directory of Open Access Journals (Sweden)

    Pei Liu

    2017-09-01

    Full Text Available The mutual-assistance compatibility of Cyperi Rhizoma (Xiangfu, XF and Angelicae Sinensis Radix (Danggui, DG, Chuanxiong Rhizoma (Chuanxiong, CX, Paeoniae Radix Alba (Baishao, BS, or Corydalis Rhizoma (Yanhusuo, YH, found in a traditional Chinese medicine (TCM named Xiang-Fu-Si-Wu Decoction (XFSWD, can produce synergistic and promoting blood effects. Nowadays, XFSWD has been proved to be effective in activating blood circulation and dissipating blood stasis. However, the role of the herb pairs synergistic effects in the formula were poorly understood. In order to quantitatively assess the compatibility effects of herb pairs, mass spectrometry-based untargeted metabolomics studies were performed. The plasma and urine metabolic profiles of acute blood stasis rats induced by adrenaline hydrochloride and ice water and administered with Cyperi Rhizoma—Angelicae Sinensis Radix (XD, Cyperi Rhizoma—Chuanxiong Rhizoma (XC, Cyperi Rhizoma—Paeoniae Radix Alba (XB, Cyperi Rhizoma—Corydalis Rhizoma (XY were compared. Relative peak area of identified metabolites was calculated and principal component analysis (PCA score plot from the potential markers was used to visualize the overall differences. Then, the metabolites results were used with biochemistry indicators and genes expression values as parameters to quantitatively evaluate the compatibility effects of XF series of herb pairs by PCA and correlation analysis. The collective results indicated that the four XF herb pairs regulated glycerophospholipid metabolism, steroid hormone biosynthesis and arachidonic acid metabolism pathway. XD was more prominent in regulating the blood stasis during the four XF herb pairs. This study demonstrated that metabolomics was a useful tool to efficacy evaluation and compatibility effects of TCM elucidation.

  20. Sesquiterpene lactones from the Yugoslavian wild growing plant families Asteraceae and Apiaceae (REVIEW

    Directory of Open Access Journals (Sweden)

    MILUTIN STEFANOVIC

    1999-08-01

    Full Text Available 1. Introduction 2. Results 3. Asteraceae 3.1. Genus Artemisia L. 3.1.1. Artemisia annua L. 3.1.2. Artemisia vulgaris L. 3.1.3. Artemisia absinthium L. (warmwood 3.1.4. Artemisia scoparia W. et K. 3.1.5. Artemisia camprestris L. 3.2. Genus Ambrosia L. 3.2.1. Ambrosia artemisiifolia L. (the common rag weed 3.3. Genus Tanacetum L. (syn. Chrysanthemum L. 3.3.1. Tanacetum parthenium L. (feverfew 3.3.2. Tanacetum serotinum L. 3.3.3. Tanacetum vulgare L. (tansy 3.3.4. Tanacetum macrophyllum Willd. 3.3.5. Tanacetum corymbosum L. 3.4. Genus Telekia Baumg. 3.4.1. Telekia speciosa (Schreb. Baumg. 3.5. Genus Inula L. 3.5.1. Inula helenium L. 3.5.2. Inula spiraeifolia L. 3.6. Genus Eupatorium L. 3.6.1. Eupatorium cannabinum L. 3.7. Genus Achillea L. 3.7.1. Achillea abrotanoides Vis. 3.7.2. Achillea millefolium subsp. pannonica 3.7.3. Achillea crithmifolia W. et K. 3.7.4. Achillea clypeolata Sibth. et Sm. 3.7.5. Achillea serbica Nyman 3.7.6. Achillea depressa Janka 3.8. Genus Anthemis L. 3.8.1. Anthemis carpatica Willd. 3.8.2. Anthemis cretica L. subsp. cretica 3.9. Genus Centaurea L. 3.9.1. Centaurea derventana Vis. et Panc. 3.9.2. Centaurea kosaninii Hayek 3.9.3. Centaurea solstitialis L. 4. Apiaceae 4.1. Genus Laserpitium L. 4.1.1. Laserpitium siler L. 4.1.2. Laserpitium marginatum L. 4.1.3. Laserpitium latifolium L. 4.1.4. Laserpitium alpinum W. K. 4.2. Genus Angelica L. 4.2.1. Angelica silvestris L. 4.3. Genus Peucedanum L. 4.3.1. Peucedanum austriacum (Jacq. Koch

  1. Botanical Provenance of Traditional Medicines From Carpathian Mountains at the Ukrainian-Polish Border

    Directory of Open Access Journals (Sweden)

    Weronika Kozlowska

    2018-04-01

    Full Text Available Plants were an essential part of foraging for food and health, and for centuries remained the only medicines available to people from the remote mountain regions. Their correct botanical provenance is an essential basis for understanding the ethnic cultures, as well as for chemical identification of the novel bioactive molecules with therapeutic effects. This work describes the use of herbal medicines in the Beskid mountain ranges located south of Krakow and Lviv, two influential medieval centers of apothecary tradition in the region. Local botanical remedies shared by Boyko, Lemko, and Gorale ethnic groups were a part of the medieval European system of medicine, used according to their Dioscoridean and Galenic qualities. Within the context of ethnic plant medicine and botanical classification, this review identified strong preferences for local use of St John's-wort (Hypericum perforatum L., wormwood (Artemisia absinthium L., garlic (Allium sativum L., gentian (Gentiana lutea L., lovage (Levisticum officinale W.D.J. Koch, and lesser periwinkle (Vinca minor L.. While Ukrainian ethnic groups favored the use of guilder-rose (Viburnum opulus L. and yarrow (Achillea millefolium L., Polish inhabitants especially valued angelica (Angelica archangelica L. and carline thistle (Carlina acaulis L.. The region also holds a strong potential for collection, cultivation, and manufacture of medicinal plants and plant-based natural specialty ingredients for the food, health and cosmetic industries, in part due to high degree of biodiversity and ecological preservation. Many of these products, including whole food nutritional supplements, will soon complement conventional medicines in prevention and treatment of diseases, while adding value to agriculture and local economies.

  2. Epistemologia e Feminismo

    OpenAIRE

    Williams, Priscila

    2018-01-01

    0 presente artigo busca compreender o entendimento de ciência e quais são seus limites. Além disso, apresenta um olhar feminista sobre a ciência, apresentando outra forma de validar o conhecimento através da Epistemologia Feminista.

  3. A formação dos salários nos setores público e privado

    OpenAIRE

    Marconi, Nelson

    2010-01-01

    Este trabalho visa comprovar a existência de segmentação entre os mercados de trabalho público e privado, evidenciada através dos diferenciais salariais e das distintas regras de formação de salários em ambos, buscando discutir de modo mais detalhado quais seriam estas regras no setor público.

  4. Dermatologia comparativa Comparative Dermatology

    Directory of Open Access Journals (Sweden)

    Hiram Larangeira de Almeida Jr

    2005-06-01

    Full Text Available Demonstra-se o quadro exuberante dos angiofibromas faciais em paciente do sexo masculino, de 32 anos, com esclerose tuberosa, os quais podem ser comparados com amoras.The impressive facial angiofibromas, from a 32 year-old male paciente, with the classical features of tuberous sclerosis, were compared with mulberries.

  5. Validação de simulações combinadas usando programas de simulação de energia do edifício e programas de transferência de calor, ar e umidade em componentes construtivos

    NARCIS (Netherlands)

    Costola, D.; Blocken, B.J.E.; Hensen, J.L.M.

    2011-01-01

    Desempenho higrotérmico dos edifícios tem sido estudado usando uma variedade de programas de computador, os quais consideram determinados domínios geométricos (exterior, envelope e interior) e físicos (calor, ar e umidade). Estes programas podem ser classificados em três principais grupos: programas

  6. Ümber mõtestades piire ja kaugust = Distance Between the Vision and the Context / Maia Tüür

    Index Scriptorium Estoniae

    Tüür, Maia

    2006-01-01

    Musee du Quai Branly Pariisis. Arhitekt Jean Nouvel, maastikuarhitekt Gilles Clement. Pargi üldskeemi kujundab teede ja pinkide võrgustik, mis põhineb kilpkonna kilbi mustril. Yann Kersale teosest pargis. Maja Seine'i-äärset fassaadi katab Patrick Blanci loodud taimevaip

  7. Ocorrência familiar de impressão basilar

    Directory of Open Access Journals (Sweden)

    José Alberto Gonçalves da Silva

    1978-09-01

    Full Text Available Os autores apresentaram os resultados clínicos e radiológicos de 9 membros de uma família, dos quais dois foram submetidos ao tratamento neurocirúrgico de impressão basilar e malformação de Arnold-Chiari.

  8. JPRS Report: Near East & South Asia.

    Science.gov (United States)

    1992-06-16

    professors raised a provocative issue that we discussed for several successive weeks: the conceptual democracy that is suitable to be a model...this matter in the framwork of and with respect for the right of peoples to self-determination," Maurice Gourdault-Montagne, deputy Quai d’Orsay

  9. Importância da cintilografia com gálio-67 no linfoma cutâneo primário de células B: relato de dois casos

    OpenAIRE

    Attab,Cyomara Sanches; Moriguchi,Sônia Marta; Paton,Eduardo José Alencar; Alencar,Mário Henrique Leite de; Rocha,Euclides Timóteo da

    2010-01-01

    Os autores relatam dois casos de linfoma cutâneo de células B, nos quais o correto estadiamento, tratamento e seguimento foram possíveis graças à combinação de exames convencionais e a cintilografia com gálio-67.

  10. China Back in the Frame

    NARCIS (Netherlands)

    Poel, van der R.H.H.

    2013-01-01

    An article on an early set of three Chinese export harbourviews in the Rijksmuseum Amsterdam: View on Macau, the Reach of Whampoa, and the Quai of Canton. The paintings once belonged to the famous Chinese collection of J.Th. Royer, the 18th century collector of Chinese art. They are in the

  11. Propagation Influences on Digital Transmission Systems: Problems and Solutions Held at Athens, Greece on 4-8 June 1984.

    Science.gov (United States)

    1984-06-08

    compared with predictions of dispersion. The predictions considerably underestimated the measured dispersion, but the inclusion of a beam hro~ adening ...41 ’ii Nl A TRANSMISSION ASYNCHRONE A FORT ETALEMENT DE SPECTRE Par- M. SCHILLIGER et C. LELOUP - MT RADIOPROFESSIONNE.LLE 46, Quai Alphonse le Gallo

  12. The Chemistry of Brazilian Lauraceae LXXI. Styrylpyrones of Aniba panurensis and A. permollis

    OpenAIRE

    Motidome, Mário; Gottlieb, Otto R.; Kubitzki, Klaus

    1982-01-01

    RESUMO Amostras das madeiras de Aniba panuransis (Meissn.) Mez e de A. permollis (Nees) Mez (família Lauraceae) contém 6-estiril -2-pironas, as quais são respectivamente, o composto não substituído e seu derivado metoxilado na posição 4.

  13. Experimental study of inhibitory effects of diallyl trisulfide on the growth of human osteosarcoma Saos-2 cells by downregulating expression of glucose-regulated protein 78

    Directory of Open Access Journals (Sweden)

    Zhang Y

    2018-01-01

    Full Text Available Yue Zhang,1,* Wen-Peng Xie,1,* Yong-Kui Zhang,2 Yi-Qiang Chen,3 Dong-Li Wang,2 Gang Li,2 Dong-Hui Guan2 1First Clinical Medical College, Shandong University of Traditional Chinese Medicine, Jinan, People’s Republic of China; 2Department of Orthopedics, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, People’s Republic of China; 3Department of Orthopedics, The First People’s Hospital of Taian City, Taian, People’s Republic of China *These authors contributed equally to the paper Background: Diallyl trisulfide (DATS is a natural organic sulfur compound isolated from garlic that has good anticancer activity according to many previous reports. There are many studies pointing out that DATS can downregulate expression of the glucose-regulated protein 78 (GRP78, which is associated with poor prognosis and drug resistance in various types of human cancers. However, it remains unknown whether DATS has the same effect on human osteosarcoma cells. This study attempted to clarify the potential molecular mechanisms of the action of DATS in human osteosarcoma Saos-2 cells.Methods: We used an inverted phase microscope and immunofluorescent staining to observe the morphological changes of Saos-2 cells after being cultured in different concentrations of DATS (0, 25, 50, and 100 µM for 24 h, or for four time periods (24, 48, 72, and 96 h in the same DATS concentration (50 µM. Quantitative real-time polymerase chain reaction and Western blot were used to detect the expression level of GRP78 mRNA and proteins in Saos-2 cells. GRP78 expression was suppressed in Saos-2 cells by utilizing small-interfering RNA, and the cells were subsequently used to study the anti-proliferative effects of DATS treatment.Results: The expression level of GRP78 mRNA and proteins was significantly downregulated due to the increased concentration and effective times of DATS (P<0.05. In addition, there were significant associations between GRP78

  14. [Secular trends of height among Chinese students aged 17 in 18 ethnic minorities from 1985 to 2010].

    Science.gov (United States)

    Song, Yi; Hu, Pei-jin; Zhang, Bing; Ma, Jun

    2015-06-18

    To analyze the secular trends of height among Chinese students aged 17 in different ethnic minorities from 1985 to 2010. A total of 18 Chinese ethnic minorities' students, including Mongolian, Hui, Uygur, Zhuang, Korean, Tibetan, Miao, Buyi, Dong, Bai, Tujia, Hani, Dai, Lisu, Wa, Nakhi, Tu and Qiang as subjects were sampled from the 1985, 1995, 2000, 2005 and 2010 Chinese National Surveys on Students' Constitution and Health. The heights of 17 years old people by gender in various ethnic minorities were analyzed and compared. From 1985 to 2010, the increments of adult heights increased significantly in many ethnic minorities' boys. In 2010, the average height of boys aged 17 years in each minority group was higher than 162 cm and was higher than 170 cm among boys from Hui, Mongolian and Korean groups. The ethnics with height growth rates of more than 2 cm per decade in boys were Hui (2.64 cm/decade) and Dong (2.05 cm/decade) and the ethnics with height growth rates of more than 1 cm per decade were Korean (1.99 cm/decade), Tibetan (1.90 cm/decade), Hani (1.80 cm/decade) and the other 9 minority groups. The average height of girls aged 17 years in each minority group was higher than 150 cm in 2010. The heights showed an upward trend in 15 minority groups, but with different degrees. The ethnics with height growth rates of more than 1 cm per decade were Hui (1.56 cm/decade) and Korean (1.29 cm/decade). The increments that were significant between 1985 and 2010 were Hui (3.89 cm), Korean (3.23 cm), Dong (2.35 cm) and the other 6 minority groups (Pminority groups during the past 25 years, but there was an obvious disequilibrium among various ethnic minorities. We should pay more attention to the minority groups with poor growth and give them more help. Meanwhile, we should also pay attention to the negative effects of the secular growth trend on those minority groups with fast increasing adult height.

  15. Herbal Prescriptions and Medicinal Herbs for Parkinson-Related Rigidity in Korean Medicine: Identification of Candidates Using Text Mining.

    Science.gov (United States)

    Park, So Hyun; Hwang, Min Seob; Park, Hye Jin; Shin, Hwa Kyoung; Baek, Jin Ung; Choi, Byung Tae

    2018-03-27

    Dongeuibogam (DongYiBaoGian), one of the most important books in Korean medicine, comprises a comprehensive summary of all traditional medicines of North-East Asia before the 17th century. This medicinal literature was mined to establish a list of candidate herbs to treat Parkinson-related rigidity. A systematic search for terms describing Parkinson-related rigidity and candidate prescriptions for the treatment of Parkinson-related rigidity in the Dongeuibogam was performed. A high-frequency medicinal herb combination group and candidates for the treatment of Parkinson-related rigidity were also selected through an analysis of medicinal herb combination frequencies. The existing literature pertaining to the potential effects of candidate herbs for Parkinson-related rigidity was reviewed. Ten medicinal herb candidates for the treatment of Parkinson-related rigidity were selected, and their respective precedent studies were analyzed.

  16. EU Energy Law. Volume 2. EU Competition Law and Energy Markets. 2. ed.

    International Nuclear Information System (INIS)

    Cabau, E.; Jones, C.; Hancher, L.; Kjoelbye, L.; Landes, V.; Van der Woude, M.

    2007-09-01

    This completely revised and reworked second edition: incorporates the conclusions and consequences of the Sectoral Energy Competition Enquiry; contains an entirely reworked section on anti-competitive agreements and practices; examines in detail the developments in individual cases concerning long-term capacity reservation and sales/purchase agreements; considers recent developments on cases concerning collusion on price and quantity restrictions; looks into detail at the consequences of the Sectoral enquiry on abuse of a dominant position, particularly regarding discrimination in network access; revises the section on merger control to take account of developments in the methodology in defining markets and defining dominance /significant impediment of competition from the Sectoral enquiry; includes major new merger cases: Endesa, GDF/Suez, E.ON/MOL, DONG; and finally updates the State Aid section to take account of new decisions on renewable support schemes, security of supply

  17. Development of Neutron Activation Analysis for Scientific Interpretation on Cultural Properties

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Gyu Ho; Kim, Na Young; Ko, Min Chung; Kim, Min Ji; Cho, Su Mi; Kang, Ji Eun [Kongju National University, Gongju (Korea, Republic of)

    2010-05-15

    This research is tried to set up the application of neutron activation analysis and to evaluate the historical information about ceramics materials at production kilns for the standardized technology of NAA. This project is measured the 112 samples from Jijong-dong, Daejeon and 4 production kiln sites in Kyongsangdo by using NAA and XRF and classified as types and production site by PCA and applied of factor analysis, discruminant analysis and cluster analysis. As the results, we know that it is classified as pottery and roof tile as measured 11 elements and that it is not classified major and trace elements as the production kiln sites because raw materials is 2nd clay. At last, it is investigated the comparative evaluation of raw material as production kiln sites by cluster analysis as the basis of the data of NA

  18. Modulation of Estrogen Chemical Carcinogenesis by Botanical Supplements used for Postmenopausal Women’s Health

    Science.gov (United States)

    Snelten, Courtney S.; Dietz, Birgit; Bolton, Judy L.

    2012-01-01

    Breast cancer risk has been associated with long-term estrogen exposure including traditional hormone therapy (HT, formally hormone replacement therapy). To avoid traditional HT and associated risks, women have been turning to botanical supplements such as black cohosh, red clover, licorice, hops, dong gui, and ginger to relieve menopausal symptoms despite a lack of efficacy evidence. The mechanisms of estrogen carcinogenesis involve both hormonal and chemical pathways. Botanical supplements could protect women from estrogen carcinogenesis by modulating key enzymatic steps [aromatase, P4501B1, P4501A1, catechol-O-methyltransferase (COMT), NAD(P)H quinone oxidoreductase 1 (NQO1), and reactive oxygen species (ROS) scavenging] in estradiol metabolism leading to estrogen carcinogenesis as outlined in Figure 1. This review summarizes the influence of popular botanical supplements used for women’s health on these key steps in the estrogen chemical carcinogenesis pathway, and suggests that botanical supplements may have added chemopreventive benefits by modulating estrogen metabolism. PMID:24223609

  19. How to improve the design of the electrical system in future wind power plants

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Holbøll, Joachim; Bak, C. L.

    2009-01-01

    This paper presents three topics which are important for better performance of future wind farms. The topics are investigated in three coordinated Ph.D. projects ongoing at the Technical University of Denmark (DTU), Aalborg University (AAU) and DONG Energy. The objective of all projects is to imp...... and wind farm transformers, and to develop a methodology on how to select appropriate equipment for the power system, control system and protection system....... is to improve the understanding of the main electrical components in wind farms, based on available information, measurement data and simulation tools. The aim of these projects is to obtain validated models of wind turbine (WT) generators, WT converters, WT transformers, submarine cables, circuit breakers...

  20. HVDC Connected Offshore Wind Power Plants: Review and Outlook of Current Research

    DEFF Research Database (Denmark)

    Glasdam, Jakob; Zeni, Lorenzo; Gryning, Mikkel

    2013-01-01

    This paper presents a state-of-the-art review on grid integration of large offshore wind power plants (OWPPs) using high voltage direct voltage (HVDC) for grid connection. The paper describes in detail selected challenges hereto and presents how DONG Energy Wind Power (DEWP) is addressing...... these challenges through three coordinated PhD projects in close collaboration with leading academia within the field. The overall goal of these projects is to acquire in-depth knowledge of relevant operating phenomena in the offshore OWPP grid, rich with power electronics devices (PEDs) such as the HVDC...... and the PED widely used in the wind turbine generators (WTGs). Challenges hereto include PED control system interaction (from a stability point of view), assessment of the quality of vendor supplied control systems and their robustness against e.g. short circuits and load rejection. Furthermore, the outcome...

  1. POSSPOW: Possible Power of Offshore Wind Power Plants

    DEFF Research Database (Denmark)

    Giebel, Gregor; Göçmen, Tuhfe; Sørensen, Poul Ejnar

    2013-01-01

    Introduction In recent years, the very large offshore wind farms were designed as wind power plants, including possibilities to contribute to the stability of the grid by offering grid services (also called ancillary services). One of those services is reserve power, which is achieved by down......-regulating the wind farm from its maximum possible power. The power can be ramped up quite quickly, but the influence of wakes makes it difficult to assess the exact amount of down-regulation available to sell. Currently, Transmission System Operators (TSOs) have no real way to determine exactly the possible power...... will be verified on some of the large offshore wind farms owned by Vattenfall, and possibly in a DONG Energy wind farm too. Dedicated experiments to the wind flow in large offshore wind farms are planned. Main body of abstract Modern wind turbines have a SCADA signal called possible power. In normal operation...

  2. The Research on the Impact of Management Level's Charismatic Leadership Style on Miners' Unsafe Behavior.

    Science.gov (United States)

    Li, Hongxia; Di, Hongxi; Tian, Shuicheng; Li, Jian

    2015-01-01

    The aim of this study is research the impact of management level's charismatic leadership style on miners' unsafe behavior by using the questionnaires on charismatic leadership style, safety attitude and the miners' unsafe behavior measurement to investigate 200 employees in Shen Dong Company. The research results suggest that management level's charismatic leadership style have very important influence on miners' unsafe behavior and the influence is affected by the safety attitude which is the intermediary function. In the end, this study propose advice on how to improve the coal mine enterprise managers charismatic leadership style in the coal mine enterprise's safety management work, including attach great importance to a variety of incentive methods, set up safety moral models, practice of inductive leadership concept, create a good atmosphere of safety, etc for reference for coal mining enterprises.

  3. Human Reliability analysis for digitized nuclear power plants: Case study on the LingAo II nuclear power plant

    Energy Technology Data Exchange (ETDEWEB)

    Zou, Yan Hua; Zhang, Li [Institute of Human Factors Engineering AND Safety Management, Hunan Institute of Technology, Hengyang (China); Dai, Cao; Li, Peng Cheng; Qing, Tao [Human Factors Institute, University of South China, Hengyang (China)

    2017-03-15

    The main control room (MCR) in advanced nuclear power plants (NPPs) has changed from analog to digital control system (DCS). Operation and control have become more automated, centralized, and accurate due to the digitalization of NPPs, which has improved the efficiency and security of the system. New issues associated with human reliability inevitably arise due to the adoption of new accident procedures and digitalization of main control rooms in NPPs. The LingAo II NPP is the first digital NPP in China to apply the state-oriented procedure. In order to address issues related to human reliability analysis for DCS and DCS + state-oriented procedure, the Hunan Institute of Technology conducted a research project based on a cooperative agreement with the LingDong Nuclear Power Co. Ltd. This paper is a brief introduction to the project.

  4. Compilation of Published Estimates of Annual Geocenter Motions Using Space Geodesy

    Science.gov (United States)

    Elosegui, P.

    2005-01-01

    The definition of the term "geocenter motion" depends on the adopted origin of the reference frame. Common reference frames used in Space Geodesy include: the center of mass of the whole Earth (CM), the center of mass of the Solid Earth without mass load (CE), and the center of figure of the outer surface of the Solid Earth (CF). There are two established definitions of the term geocenter: one, the vector offset of CF relative to CM and, two, the reverse, the vector offset of CM relative to CF. Obviously, their amplitude is the same and their phase differs by 180 deg. Following Dong et al. [2003], we label the first X(sub CF, sup CM) and the second X(sup CF, sup CM) (i.e., the superscript represents the frame, the subscript represents any point in the frame).

  5. Cultivation of kelp species in the Limfjord, Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Wegeberg, S.

    2010-04-15

    To evaluate the scope of the work and yield of cultivating kelp species in the Danish waters for DONG Energy, Denmark, a pilot?scale cultivation project was initiated in connection with the review of the potential of algal biomass for bio?energy production in Denmark. Two species of large brown algae, sea girdles (Laminaria digitata) and sweet tangle (Saccharina latissima) were cultivated with the expectation to gain maximum biomass yield, partly because of the species' size and partly because of their growth strategy. The result of the pilot study was that sugar seaweed's average maximum length was 7-8 cm, while finger seaweed's length was only 5 cm. The relative small yield is attributable to an overgrowth of sessile animals (hydroids and sea squirts). (ln)

  6. Hierarchical model-based predictive control of a power plant portfolio

    DEFF Research Database (Denmark)

    Edlund, Kristian; Bendtsen, Jan Dimon; Jørgensen, John Bagterp

    2011-01-01

    One of the main difficulties in large-scale implementation of renewable energy in existing power systems is that the production from renewable sources is difficult to predict and control. For this reason, fast and efficient control of controllable power producing units – so-called “portfolio...... design for power system portfolio control, which aims specifically at meeting these demands.The design involves a two-layer hierarchical structure with clearly defined interfaces that facilitate an object-oriented implementation approach. The same hierarchical structure is reflected in the underlying...... optimisation problem, which is solved using Dantzig–Wolfe decomposition. This decomposition yields improved computational efficiency and better scalability compared to centralised methods.The proposed control scheme is compared to an existing, state-of-the-art portfolio control system (operated by DONG Energy...

  7. Teaching Pragmatic Particles in the LCTL Classroom

    Directory of Open Access Journals (Sweden)

    Faizah Sari

    2008-01-01

    Full Text Available The success and effectiveness of teaching the LCTL class-room depend on the LCTL research. The study investigated the into-nation contours of seven Indonesian pragmatic particles (kan, ya, kok, lho, dong, deh, and sih to review the functions of the particles. Vide-otaped data of naturally occurring conversations by native speakers of Indonesian were collected. Results indicated the number of into-nation contours for the Indonesian pragmatic particles used by the speakers to organize information (for example, to extend common ground and mark shared knowledge and to convey the speaker’s ex-pression (for example, surprise and emphasis. The particle contour analysis forms a natural link between grammatical and interactional competence and bears an important LCTL pedagogical consequence in terms of both improving teaching materials and bringing the cul-ture closer to the learner. Based on the findings, four strategies in teaching the LCTL classroom are recommended.

  8. The anatomy, taphonomy, taxonomy and systematic affinity of Markuelia: Early Cambrian to Early Ordovician scalidophorans

    Science.gov (United States)

    Dong, X.-P.; Bengtson, S.; Gostling, N.J.; Cunningham, J.A.; Harvey, T.H.P.; Kouchinsky, A.; Val'Kov, A.K.; Repetski, J.E.; Stampanoni, M.; Marone, F.; Donoghue, P.C.J.

    2010-01-01

    Markuelia is a vermiform, annulated introvertan animal known as embryonic fossils from the Lower Cambrian to Lower Ordovician. Analysis of an expanded and revised dataset for Introverta shows that the precise position of Markuelia within this clade is dependent on the taxa included. As a result, Markuelia is assigned to the scalidophoran total group to reflect uncertainty as to whether it is a stem-scalidophoran or a stem-priapulid. The taxonomy of the genus is revised to provide an improved taxonomic framework for material assigned to Markuelia. Five species are recognized: M. secunda Val'kov, M. hunanensis Dong and Donoghue, M. lauriei Haug et al., M. spinulifera sp. nov. and M. waloszeki sp. nov. Finally, the preservation of Markuelia is evaluated in the light of both the taphonomy of the fossil embryos themselves and the experimental taphonomy of the priapulid Priapulus caudatus, which has been proposed as both a close relative and an anatomical analogue of Markuelia. ?? The Palaeontological Association.

  9. Genotype-Dependent Effect of Exogenous Nitric Oxide on Cd-induced Changes in Antioxidative Metabolism, Ultrastructure, and Photosynthetic Performance in Barley Seedlings (Hordeum vulgare)

    DEFF Research Database (Denmark)

    Chen, Fei; Wang, Fang; Sun, Hongyan

    2010-01-01

    M Cd increased the accumulation of O2•-, H2O2, and malondialdehyde (MDA) but reduced plant height, chlorophyll content, net photosynthetic rate (P n), and biomass, with a much more severe response in the Cd-sensitive genotype. Antioxidant enzyme activities increased significantly under Cd stress......A greenhouse hydroponic experiment was performed using Cd-sensitive (cv. Dong 17) and Cd-tolerant (Weisuobuzhi) barley seedlings to evaluate how different genotypes responded to cadmium (Cd) toxicity in the presence of sodium nitroprusside (SNP), a nitric oxide (NO) donor. Results showed that 5 μ...... in the roots of the tolerant genotype, whereas in leaves of the sensitive genotype, superoxide dismutase (SOD) and ascorbate peroxide (APX), especially cytosol ascorbate peroxidase (cAPX), decreased after 5-15 days Cd exposure. Moreover, Cd induces NO synthesis by stimulating nitrate reductase and nitric oxide...

  10. Mobilization for HIV Voluntary Counseling and Testing Services in Vietnam: Clients' Risk Behaviors, Attitudes and Willingness to Pay.

    Science.gov (United States)

    Nguyen, Long Hoang; Tran, Bach Xuan; Nguyen, Nhung Phuong; Phan, Huong Thu Thi; Bui, Trang Thu; Latkin, Carl A

    2016-04-01

    A multi-site survey was conducted on a sample of 365 clients to assess their willingness to pay for HIV voluntary counseling and testing (VCT) services in Ha Noi and Nam Dinh province, two epicenters of Vietnam. By using contingent valuation technique, the results showed that most of respondents (95.1 %) were willing to pay averagely 155 (95 % CI 132-177) thousands Vietnam Dong (~US $7.75, 2013) for a VCT service. Clients who were female, had middle income level, and current opioid users were willing to pay less; meanwhile clients who had university level of education were willing to pay more for a VCT service. The results highlighted the high rate of willingness to pay for the service at a high amount by VCT clients. These findings contribute to the implementation of co-payment scheme for VCT services toward the financial sustainability of HIV/AIDS programs in Vietnam.

  11. Metal toxicity characterization factors for marine ecosystems: considering the importance of the estuary for freshwater emissions

    DEFF Research Database (Denmark)

    Dong, Yan; Rosenbaum, Ralph K.; Hauschild, Michael Zwicky

    2017-01-01

    The study develops site-dependent characterization factors (CFs) for marine ecotoxicity of metals emitted to freshwater, taking their passage of the estuary into account. To serve life cycle assessment (LCA) studies where emission location is often unknown, site-generic marine CFs were developed...... with an estuary removal process to calculate FF. BF and EF were taken from Dong et al. Environ Sci Technol 50:269–278 (2016). Site-generic marine CFs were derived from site-dependent marine CFs. Different averaging principles were tested, and the approach representing estuary discharge rate was identified...... between both methods. Accounting for estuary removal particularly influences marine ecotoxicity CFs for emission to freshwater of metals that have a strong tendency to complex-bind to particles. It indicates the importance of including estuary in the characterization modelling when dealing with those...

  12. ANALYSIS ON THE DYNAMICS OF SPATIAL DISTRIBUTION PATTERN OF MIXED SPIDER POPULATION IN RICE FIELD

    Institute of Scientific and Technical Information of China (English)

    ZhiWang; Zhe-mingYuan; Da-xiangSong; Ming-shengZhu

    2004-01-01

    The results make it clear that there are total 11 families, 29 genera and 43 species of spiders in the rice field of Dong Fang Hong Farm. Among them, there are 8 families, 19 genera and 28 species in the early rice field, and 10 families, 27 genera and 36 species in the late rice field. The spatial distribution pattern of mixed spider populations in rice fields was different during different development stages of rice plant. During the prophase, metaphase and anaphase of early rice plant development, the spatial distribution pattern of mixed spider populations was aggregative, random and aggregative respectively. During the prophase, metaphase and anaphase of late rice plant development, the spatial distribution pattern was uniform, aggregative and uniform respectively.

  13. Manuscripts on foundation of Korea nuclear power

    International Nuclear Information System (INIS)

    Park, Ik Su

    1999-12-01

    It is comprised of the manuscripts and recollections on foundation of Korea nuclear power, which includes conversation with Yoon, Se Won, conversation with Choe, Paeng Seop, conversation with Lee, Dong Jip, conversation with Lee, Sang Su, conversation with Kim, Jong Ju, conversation with Lee, Jong Hun, conversation with Youn, Yong Ryeok, conversation with Han, Pil Sun, recollection of my nuclear power by Lee, Chang Gun, recollection of safety regulation in early nuclear power by An, Yeong Ju, recollection of nuclear business in early nuclear power by Lee, Min Ha, recollection of non destructive examination by Je, Hauk, extra story related nuclear power in early period by Heo, Nam and nuclear power and I by Park,Ik Su.

  14. Wake models developed during the Wind Shadow project

    Energy Technology Data Exchange (ETDEWEB)

    Larsen, S.; Ott, S.; Pena, A.; Berg, J.; Nielsen, M.; Rathmann, O.; Joergensen, H.

    2011-11-15

    The Wind Shadow project has developed and validated improved models for determining the wakes losses, and thereby the array efficiency of very large, closely packed wind farms. The rationale behind the project has been that the existing software has been covering these types of wind farms poorly, both with respect to the densely packed turbines and the large fetches needed to describe the collective shadow effects of one farm to the next. Further the project has developed the necessary software for the use of the models. Guidelines with recommendations for the use of the models are included in the model deliverables. The project has been carried out as a collaborative project between Risoe DTU, DONG, Vattenfall, DNV and VESTAS, and it has been financed by energinet.dk grant no. 10086. (Author)

  15. The uranium of two 'private': from Jouac (Haute-Vienne) to Bertholene (Aveyron) through Saint-Pierre (Cantal)

    International Nuclear Information System (INIS)

    Guiollard, P.Ch.; Milville, G.

    2003-01-01

    In this book, the author tells us the short but intense history of some French uranium mines among the most famous ones: Jouac-Le Bernardan (Limousin) and Bertholene (Aveyron). It gives also a precious description of the discovery of the spar-fluor ore of La Charbonniere mine (Haute-Vienne) initially discovered thanks to its radioactivity (anthozonite bed) and which supplied a huge amount of fluorine. It presents the main companies (Scumra and Charbonnages du Dong-Trieu) which have exploited these deposits and also some less-known uranium mines of Aveyron, Creuse, Correze, Cantal and Limousin. The text is fully illustrated with cross sections and photos and gathers a large amount of geological and historical documents about mining techniques. (J.S.)

  16. GIS-based spatial statistical analysis of risk areas for liver flukes in Surin Province of Thailand.

    Science.gov (United States)

    Rujirakul, Ratana; Ueng-arporn, Naporn; Kaewpitoon, Soraya; Loyd, Ryan J; Kaewthani, Sarochinee; Kaewpitoon, Natthawut

    2015-01-01

    It is urgently necessary to be aware of the distribution and risk areas of liver fluke, Opisthorchis viverrini, for proper allocation of prevention and control measures. This study aimed to investigate the human behavior, and environmental factors influencing the distribution in Surin Province of Thailand, and to build a model using stepwise multiple regression analysis with a geographic information system (GIS) on environment and climate data. The relationship between the human behavior, attitudes (R Square=0.878, and, Adjust R Square=0.849. By GIS analysis, we found Si Narong, Sangkha, Phanom Dong Rak, Mueang Surin, Non Narai, Samrong Thap, Chumphon Buri, and Rattanaburi to have the highest distributions in Surin province. In conclusion, the combination of GIS and statistical analysis can help simulate the spatial distribution and risk areas of liver fluke, and thus may be an important tool for future planning of prevention and control measures.

  17. Application of thermoluminescence dating on pressed crystalline samples to determine the geological age at some areas in Eastern South, Vietnam

    International Nuclear Information System (INIS)

    Do Duy Khiem; Luu Anh Tuyen; Phan Trong Phuc; Nguyen Thi Ngoc Hue; Pham Thi Hue; La Ly Nguyen; Ha Quang Hai

    2016-01-01

    The terrestrial part of eastern margin of the Mekong Basin is formed by outcrop of the pre-Holocen Cenozoic sequence. Almost previous studies concerned in using relative methods in geologic dating at the Mekong Basin, therefore, the ages of its stratigraphy are still unclear. The thermoluminescence (TL) dating was considered as one of the precise methods in geologic dating. In our study, we used TL dating for some areas at Eastern South, Vietnam including Ba Mieu Formation and the Thu Duc Formation at some areas in Dong Nai province and Ho Chi Minh City. This work has been the first application of TL for in geologic dating by a domestic laboratory. Experimental measurements of TL were performed using pressed crystalline quartz specimens from sediment samples. The results show that the Ba Mieu Formation was deposited about 238±22 ka and the Thu Duc Formation was deposited about 199±21 ka. (author)

  18. Induction of mutation on mulberry (morus alba L.) by using in vitro techniques in combination with gamma irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen Van Vinh [Nuclear Research Institute, Department of Biotechnology, Dalat (Viet Nam)

    2001-03-01

    Mutation induction and selection of desired characters on mulberry will contribute to industrialization and modernization in agricultural development in Vietnam. The objectives are to conduct biochemical and physiological analyses of collected mulberry varieties and to improve techniques for boosting yield and better quality in some mulberry genotypes by using in vitro technique combined with gamma irradiation. Two mulberry varieties named BauDen and VA 186 were used. Cuts of them were treated with gamma rays of Co-60, cultivated in experimental field with use of vitro technique to rapidly isolate mutants in irradiated population and investigated for plantlets, color of leaves, etc 30 days after cultivation. The results on the mutation frequency and spectrum of variation as well as the results of selection and isolation are presented. Eleven mutated clones from the two starting varieties were obtained during 1993-99. Three of them are now being cultivated in LamDong province fields. (S. Ohno)

  19. Reactivity of iron-rich phyllosilicates with uranium and chromium through redox transition zones

    International Nuclear Information System (INIS)

    Burgos, William D.

    2016-01-01

    This project performed thermodynamic, kinetic, and mineral structural studies on the reactivity of phyllosilicate Fe(II/III) with metal-reducing bacteria, and with two important poly-valent DOE contaminants (chromium and uranium) that show high mobility in their oxidized state. We focused on Fe-bearing phyllosilicates because these are important components of the reactive, fines fraction of Hanford, Oak Ridge, and Idaho National Laboratory sediments. Iron-bearing phyllosilicates strongly influence the redox state and mobility of Cr and U because of their limited hydraulic conductivity, high specific surface area, and redox reactivity. This was a collaborative project between Penn State (W.D. Burgos - PI), Miami University (H. Dong - Co-PI), and Argonne National Laboratory (K. Kemner and M. Boyanov - Co-PIs). Penn State and Miami University were funded together but separately from ANL. This report summarizes research findings and publications produced by Penn State and Miami University.

  20. Bulk locality and entanglement swapping in AdS/CFT

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, William R. [Center for Quantum Mathematics and Physics (QMAP),Department of Physics, University of California,Davis, CA 95616 (United States)

    2017-03-29

    Localized bulk excitations in AdS/CFT are produced by operators which modify the pattern of entanglement in the boundary state. We show that simple models — consisting of entanglement swapping operators acting on a qubit system or a free field theory — capture qualitative features of gravitational backreaction and reproduce predictions of the Ryu-Takayanagi formula. These entanglement swapping operators naturally admit multiple representations associated with different degrees of freedom, thereby reproducing the code subspace structure emphasized by Almheiri, Dong, and Harlow. We also show that the boundary Reeh-Schlieder theorem implies that equivalence of certain operators on a code subspace necessarily breaks down when non-perturbative effects are taken into account (as is expected based on bulk arguments).