WorldWideScience

Sample records for dispositivos implantables intravasculares

  1. An Implantable Intravascular Pressure Sensor for a Ventricular Assist Device

    Directory of Open Access Journals (Sweden)

    Luigi Brancato

    2016-08-01

    Full Text Available The aim of this study is to investigate the intravascular application of a micro-electro-mechanical system (MEMS pressure sensor to directly measure the hemodynamic characteristics of a ventricular assist device (VAD. A bio- and hemo-compatible packaging strategy is implemented, based on a ceramic thick film process. A commercial sub-millimeter piezoresistive sensor is attached to an alumina substrate, and a double coating of polydimethylsiloxane (PDMS and parylene-C is applied. The final size of the packaged device is 2.6 mm by 3.6 mm by 1.8 mm. A prototype electronic circuit for conditioning and read-out of the pressure signal is developed, satisfying the VAD-specific requirements of low power consumption (less than 14.5 mW in continuous mode and small form factor. The packaged sensor has been submitted to extensive in vitro tests. The device displayed a temperature-independent sensitivity (12 μ V/V/mmHg and good in vitro stability when exposed to the continuous flow of saline solution (less than 0.05 mmHg/day drift after 50 h. During in vivo validation, the transducer has been successfully used to record the arterial pressure waveform of a female sheep. A small, intravascular sensor to continuously register the blood pressure at the inflow and the outflow of a VAD is developed and successfully validated in vivo.

  2. Evolución de los pacientes con complicaciones locales en la bolsa del generador de un dispositivo implantable

    OpenAIRE

    Izquierdo,Maite; Bonanad,Clara; Madrazo,Inés; Ferrero,Ángel; Martínez,Ángel; Morell,Salvador; Chorro,Javier; Ruiz-Granell,Ricardo

    2014-01-01

    Objetivo: Las recomendaciones para la extracción completa de la bolsa de dispositivos implantables por problemas locales han cambiado. Analizamos la evolución entre 2002 y 2010 de los pacientes que requirieron una intervención por una complicación local en nuestro centro. Métodos: Ochenta y tres pacientes tuvieron un problema local de la bolsa que se clasificó según integridad de la piel: 1. Íntegra y 2. Abierta, y el tipo de intervención realizada: 1. Conservadora, 2. Extracción parcial y 3....

  3. Interacciones entre dispositivos cardíacos implantables y modalidades fisioterapéuticas: ¿Mito o realidad?

    Directory of Open Access Journals (Sweden)

    Genevieve C. Digby

    2011-04-01

    Full Text Available La fisioterapia se ha transformado en una especialidad que claramente incide en la calidad de vida de nuestros pacientes. En poblaciones añosas, el uso de fisioterapia incluye múltiples modalidades para un alto número de distintas enfermedades. Varios informes sobre posibles interacciones negativas entre las distintas modalidades de fisioterapia y los dispositivos cardíacos implantables (marcapasos y cardiodesfibriladores han sido publicados en los últimos aňos. A pesar de ello, existe muy poca evidencia y guías precisas para identificar cuáles son las modalidades de fisioterapia seguras a utilizar en esta población de pacientes. En la siguiente revisión, nos propusimos resumir las interacciones documentadas entre fisioterapia y dispositivos cardíacos implantables (DCI, discutir el estándar actual de estas prácticas e identificar las principales consideraciones que existen desde la perspectiva de un servicio de electrofisiología cardíaca, para el tratamiento adecuado en estos pacientes. Finalmente, abogamos por fortalecer la colaboración entre fisioterapeutas y electrofisiólogos, con el fin de asegurar una óptima y segura atención de este grupo de pacientes.

  4. 21 CFR 870.3375 - Cardiovascular intravascular filter.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Cardiovascular intravascular filter. 870.3375... Cardiovascular intravascular filter. (a) Identification. A cardiovascular intravascular filter is an implant that... and Revision of 2/12/90 (K90-1)” and (ii) “Guidance for Cardiovascular Intravascular Filter 510(k...

  5. Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial

    DEFF Research Database (Denmark)

    Jensen, Lisette Okkels; Mæng, Michael; Thayssen, Per

    2011-01-01

    Patients with diabetes mellitus have increased risk of in-stent restenosis after coronary stent implantation due to neointimal hyperplasia (NIH). The aim of this study was to use quantitative coronary angiography (QCA) and volumetric intravascular ultrasound (IVUS) to evaluate the effects...... of the sirolimus-eluting Cypher® stent (SES) and the zotarolimus-eluting Endeavor® stent (ZES) on angiographic late lumen loss and intima hyperplasia in diabetic patients....

  6. Intravascular ultrasound assessment of minimumlumen area and intimal hyperplasia in in-stent restenosis after drug-eluting or bare-metal stent implantation. The Nordic Intravascular Ultrasound Study (NIVUS)

    DEFF Research Database (Denmark)

    Jensen, Lisette Okkels; Vikman, Saila; Antonsen, Lisbeth

    2017-01-01

    presenting with a DES or bare-metal stent (BMS) in-stent restenosis. Methods: The ``Nordic Intravascular Ultrasound Study (NIVUS)'' study was conducted in Nordic and Baltic countries as a prospective multicenter registry. Two hundred nine patients (DES n = 121 and BMS n = 88) with instent restenosis were...

  7. Optical coherence tomography compared with intravascular ultrasound and with angiography to guide coronary stent implantation (ILUMIEN III: OPTIMIZE PCI): a randomised controlled trial.

    Science.gov (United States)

    Ali, Ziad A; Maehara, Akiko; Généreux, Philippe; Shlofmitz, Richard A; Fabbiocchi, Franco; Nazif, Tamim M; Guagliumi, Giulio; Meraj, Perwaiz M; Alfonso, Fernando; Samady, Habib; Akasaka, Takashi; Carlson, Eric B; Leesar, Massoud A; Matsumura, Mitsuaki; Ozan, Melek Ozgu; Mintz, Gary S; Ben-Yehuda, Ori; Stone, Gregg W

    2016-11-26

    Percutaneous coronary intervention (PCI) is most commonly guided by angiography alone. Intravascular ultrasound (IVUS) guidance has been shown to reduce major adverse cardiovascular events (MACE) after PCI, principally by resulting in a larger postprocedure lumen than with angiographic guidance. Optical coherence tomography (OCT) provides higher resolution imaging than does IVUS, although findings from some studies suggest that it might lead to smaller luminal diameters after stent implantation. We sought to establish whether or not a novel OCT-based stent sizing strategy would result in a minimum stent area similar to or better than that achieved with IVUS guidance and better than that achieved with angiography guidance alone. In this randomised controlled trial, we recruited patients aged 18 years or older undergoing PCI from 29 hospitals in eight countries. Eligible patients had one or more target lesions located in a native coronary artery with a visually estimated reference vessel diameter of 2·25-3·50 mm and a length of less than 40 mm. We excluded patients with left main or ostial right coronary artery stenoses, bypass graft stenoses, chronic total occlusions, planned two-stent bifurcations, and in-stent restenosis. Participants were randomly assigned (1:1:1; with use of an interactive web-based system in block sizes of three, stratified by site) to OCT guidance, IVUS guidance, or angiography-guided stent implantation. We did OCT-guided PCI using a specific protocol to establish stent length, diameter, and expansion according to reference segment external elastic lamina measurements. All patients underwent final OCT imaging (operators in the IVUS and angiography groups were masked to the OCT images). The primary efficacy endpoint was post-PCI minimum stent area, measured by OCT at a masked independent core laboratory at completion of enrolment, in all randomly allocated participants who had primary outcome data. The primary safety endpoint was procedural

  8. Protocol updated for the treatment of patients in radiotherapy with implanted cardiac devices; Protocolo actualizado para el tratamiento de pacientes en radioterapia con dispositivos cardiacos implantados

    Energy Technology Data Exchange (ETDEWEB)

    Martin Martin, G.; Bermudez Luna, R.; Rodriguez Rodriguez, C.; Lopez Fernandez, A.; Rodriguez Perez, A.; Sotoca Ruiz, A.

    2013-07-01

    Radiotherapy treatment can be safely performed in patients with pacemakers or implanted defibrillators, however, it is very important to ensure that the patient receives the minimum dose possible in your heart device. Is considered essential good coordination with the cardiology service before, during and after radiotherapy treatment for the patient safety. Finally we present a protocol updated to treat these patients in radiotherapy. (Author)

  9. El dispositivo de discapacidad

    OpenAIRE

    Alejandro Martín Contino

    2013-01-01

    Interrogando la naturalización del modelo médi - co-individual de la discapacidad, se despliega la hipótesis de concebir a la discapacidad como un dispositivo, de acuerdo a lo planteado por Michel Foucault. Así, los aspectos negativos vivencia - dos por las personas en situación de discapacidad, lejos de implicar fallas de funcionamiento de las políticas públicas, serían efectos lógicos y espera - bles de la institucionalización del modelo médico- individual, y la producción de subjetividad q...

  10. Intimal hyperplasia and vascular remodeling after everolimus-eluting and sirolimus-eluting stent implantation in diabetic patients the randomized diabetes and drug-eluting stent (DiabeDES) IV intravascular ultrasound trial

    DEFF Research Database (Denmark)

    Antonsen, Lisbeth; Maeng, Michael; Thayssen, Per

    2013-01-01

    OBJECTIVE: To evaluate the effects of the everolimus-eluting Xience™/Promus™ stent (EES) and the sirolimus-eluting Cypher™ stent (SES) on intimal hyperplasia (IH) in diabetic patients. BACKGROUND: Patients with diabetes mellitus have increased risk of in-stent restenosis after coronary stent...... implantation due to intimal hyperplasia (IH). METHODS: In a sub study of the Randomized Comparison of Everolimus-Eluting and Sirolimus-Eluting Stents in Patients Treated with Percutaneous Coronary Intervention (SORT OUT IV trial), serial intravascular ultrasound (IVUS) 10-month follow-up data were available...... in 88 patients, including 48 EES and 40 SES treated patients. IVUS endpoints included IH volume, in-stent % volume obstruction and changes in external elastic membrane (EEM) volume. RESULTS: Compared with the SES group, IH volume was increased in the EES group [median (interquartile range): 2.8 mm(3) (0...

  11. Intra-stent tissue evaluation within bare metal and drug-eluting stents > 3 years since implantation in patients with mild to moderate neointimal proliferation using optical coherence tomography and virtual histology intravascular ultrasound.

    Science.gov (United States)

    Kitabata, Hironori; Loh, Joshua P; Pendyala, Lakshmana K; Omar, Alfazir; Ota, Hideaki; Minha, Sa'ar; Magalhaes, Marco A; Torguson, Rebecca; Chen, Fang; Satler, Lowell F; Pichard, Augusto D; Waksman, Ron

    2014-04-01

    We aimed to compare neointimal tissue characteristics between bare-metal stents (BMS) and drug-eluting stents (DES) at long-term follow-up using optical coherence tomography (OCT) and virtual histology intravascular ultrasound (VH-IVUS). Neoatherosclerosis in neointima has been reported in BMS and in DES. Thirty patients with 36 stented lesions [BMS (n=17) or DES (n=19)] >3years after implantation were prospectively enrolled. OCT and VH-IVUS were performed and analyzed independently. Stents with ≥70% diameter stenosis were excluded. The median duration from implantation was 126.0months in the BMS group and 60.0months in the DES group (p 3years to stents had evidence of intimal disruption. The percentage volume of necrotic core (16.1% [9.7, 20.3] vs. 9.7% [7.0, 16.5], p=0.062) and dense calcium (9.5% [3.8, 13.6] vs. 2.7% [0.4, 4.9], p=0.080) in neointima tended to be greater in BMS-treated lesions. Intra-stent VH-TCFA (BMS vs. DES 45.5% vs. 18.2%, p=0.361) did not differ significantly. At long-term follow-up beyond 3 years after implantation, the intra-stent neointimal tissue characteristics appeared similar for both BMS and DES. Copyright © 2014 Elsevier Inc. All rights reserved.

  12. Assessing intravascular fluid status

    African Journals Online (AJOL)

    The assessment of intravascular fluid volume is a difficult undertaking in both the intensive care unit and theatre situation ... equally applicable to pulmonary capillary wedge pressure. .... airway pressure, the more difficult it becomes to interpret ...

  13. Disseminated intravascular coagulation (DIC)

    Science.gov (United States)

    ... Jr, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 141. Thachil J, Toh CH. Current concepts in the management of disseminated intravascular coagulation. Thromb Res . 2012;129 ...

  14. Intravascular malignant lymphomatosis

    International Nuclear Information System (INIS)

    Martin-Duverneuil, N.; Lafitte, F.; Chiras, J.; Mokhtari, K.; Behin, A.; Hoang-Xuan, K.

    2002-01-01

    Intravascular malignant lymphomatosis is a rare and probably often overlooked disease characterised by massive intravascular proliferation of lymphoid cells, usually with a poor prognosis. CT and MRI appearances are nonspecific; the most suggestive finding being both asymmetrical, bilateral, contrast enhancing high-signal areas on T2 weighting and infarct-like lesions of the cortex and basal ganglia. We report two patients with previously unreported dural and spinal cord involvement. (orig.)

  15. Intravascular malignant lymphomatosis

    Energy Technology Data Exchange (ETDEWEB)

    Martin-Duverneuil, N.; Lafitte, F.; Chiras, J. [Service de Neuroradiologie Charcot, Batiment Babinski, Hopital de la Salpetriere, 75013 Paris (France); Mokhtari, K. [Service de Neuropathologie, Hopital de la Salpetriere, 75013 Paris (France); Behin, A.; Hoang-Xuan, K. [Departement de Neurologie, Hopital de la Salpetriere, 75013 Paris (France)

    2002-09-01

    Intravascular malignant lymphomatosis is a rare and probably often overlooked disease characterised by massive intravascular proliferation of lymphoid cells, usually with a poor prognosis. CT and MRI appearances are nonspecific; the most suggestive finding being both asymmetrical, bilateral, contrast enhancing high-signal areas on T2 weighting and infarct-like lesions of the cortex and basal ganglia. We report two patients with previously unreported dural and spinal cord involvement. (orig.)

  16. Serial intravascular ultrasound analysis of peri-stent remodeling and proximal and distal edge effects after sirolimus-eluting or paclitaxel-eluting stent implantation in patients with diabetes mellitus

    DEFF Research Database (Denmark)

    Jensen, Lisette Okkels; Maeng, Michael; Mintz, Gary S

    2009-01-01

    Patients with diabetes have an increased risk of in-stent restenosis after coronary stent implantation. Serial intravascular ultrasound was used to study chronic arterial responses and edge effects after implantation of Cypher (Cordis, Johnson & Johnson, Miami Lakes, Florida) or Taxus (Boston......-up. The increase in peri-stent external elastic membrane (EEM) volume was more pronounced in the Taxus group (292.4 +/- 132.6 to 309.5 +/- 146.8 mm(3)) than in the Cypher group (274.4 +/- 137.2 to 275.4 +/- 140.1 mm(3); p = 0.005). Peri-stent plaque volume increased in the Taxus group (152.5 +/- 73.7 to 166.......1 +/- 85.1 mm(3)), but was unchanged in the Cypher group (153.5 +/- 75.5 to 151.5 +/- 75.8 mm(3); p = 0.002). In proximal and distal reference segments, mean lumen area decreased within the entire 5-mm edge segment (proximal and distal) because of plaque progression (distal, 5.5 +/- 3.6 to 5.8 +/- 3.7 mm(2...

  17. Intravascular pulmonary metastases

    International Nuclear Information System (INIS)

    Shepard, J.A.O.; Moore, E.H.; Templeton, P.A.; McLoud, T.C.

    1988-01-01

    The diagnosis of intravascular metastatic tumor emboli to the lungs is rarely made. The authors present a characteristic radiographic finding of intravascular lung metastases that they observed in four patients with diagnoses or right atrial myoxoma, invasive renal cell carcinoma, invasive pelvic osteosarcoma, and recurrent pelvic chondrosarcoma. Substantiation of intravascular pulmonary metastases was achieved by means of autopsy, pulmonary artery biopsy, and surgical documentation of tumor invasion of the inferior vena cava or pelvic veins. In all four cases, chest computed tomography (CT) demonstrated branching, beaded opacities extending from the hila into the periphery of the lung in the distribution of pulmonary arteries. In one case, similar findings were observed in magnetic resonance (MR) images of the chest. Follow-up studies in three cases showed progressive enlargement and varicosity of the abnormal pulmonary artery consistent with proliferation of intravascular tumor. In the case of metastatic osteosarcoma, intraluminal ossification was also observed at CT. In three of four cases, pulmonary infarction was demonstrated in the distribution of the abnormal pulmonary arteries seen at CT as small, peripheral, wedge-shaped opacities. The demonstration of progressively dilated and beaded pulmonary arteries in patients with extrathoracic malignancies is suggestive of intravascular lung metastases, particularly when accompanied by peripheral infarction

  18. Intravascular "mulberry-like" bodies

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Klebe, J G; Henriques, U V

    1988-01-01

    Intravascular "mulberry-like" bodies in a stillborn female infant with moderate maceration are reported. The histogenesis of these structures is discussed based on light-microscopic, immunohistochemical and ultrastructural findings. No demonstrable causal relation between the intravascular lesion...... and fetal death was found, the cause of death being attributed to intrauterine asphyxia. It is concluded, that intravascular "mulberry-bodies" most likely represent artifacts due to red blood cell autolysis.......Intravascular "mulberry-like" bodies in a stillborn female infant with moderate maceration are reported. The histogenesis of these structures is discussed based on light-microscopic, immunohistochemical and ultrastructural findings. No demonstrable causal relation between the intravascular lesions...

  19. Intravascular (catheter) MR imaging

    International Nuclear Information System (INIS)

    Cohen, A.M.; Hurst, G.C.; Katz, D.E.; Dverk, J.L.; Wiesen, E.J.; Czerski, L.W.; Malaya, R.; Bellon, E.M.

    1989-01-01

    Intravascular MR probes allow excellent spatial resolution and have the potential to detect arterial wall microstructure. Ultrasonic intravascular probes suggest that detailed morphologic information can assist clinical decision making. Catheter MR probes of 2--7 mm outside diameter (OD) were built of copper wire, Teflon, and parts from standard commercial catheters. The probes were connected to the surface coil receiver input of our Picker VISTA 2055HP 1.5-T imaging system. The extant (linear) body coil was used for transmit. Phantoms were constructed of coaxial glass MR tubes, filled with doped water. Watanabe rabbit aorta and human autopsy iliac artery specimens were examined within 4 hours of excision or stored by freezing. In vivo iliac arteries in dogs under general anesthesia were imaged, with percutaneous placement of the probe. Results are presented

  20. Intravascular "mulberry-like" bodies

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt; Klebe, J G; Henriques, U V

    1988-01-01

    Intravascular "mulberry-like" bodies in a stillborn female infant with moderate maceration are reported. The histogenesis of these structures is discussed based on light-microscopic, immunohistochemical and ultrastructural findings. No demonstrable causal relation between the intravascular lesions...... and fetal death was found, the cause of death being attributed to intrauterine asphyxia. It is concluded, that intravascular "mulberry-bodies" most likely represent artifacts due to red blood cell autolysis....

  1. Pelo imprevisto: dispositivos e singularidade

    Directory of Open Access Journals (Sweden)

    Artur de Vargas Giorgi

    2010-05-01

    Full Text Available http://dx.doi.org/10.5007/1984-784X.2010v10n15p159 Um dos desdobramentos das investigações de Foucault sobre os processos de subjetivação e as técnicas de governo pode ser encontrado no conceito de dispositivo. Conceito que está presente, e com grande produtividade, no pensamento de Giorgio Agamben, já que são vários os textos em que ele retoma e trabalha sua ambivalência, desenvolvendo também o seu alcance, como em O que é um dispositivo? O presente texto parte da definição de Agamben para levantar algumas questões acerca do conceito e das estratégias para lidar com ele.

  2. Dosimetry in intravascular brachytherapy

    International Nuclear Information System (INIS)

    Campos, Laelia Pumilla Botelho

    2000-03-01

    Among the cardiovascular diseases responsible for deaths in the adult population in almost all countries of the world, the most common is acute myocardial infarction, which generally occurs because of the occlusion of one or more coronary arteries. Several diagnostic techniques and therapies are being tested for the treatment of coronary artery disease. Balloon angioplasty has been a popular treatment which is less invasive than traditional surgeries involving revascularization of the myocardium, thus promising a better quality of life for patients. Unfortunately, the rate of restenosis (re-closing of the vessel) after balloon angioplasty is high (approximately 30-50% within the first year after treatment).Recently, the idea of delivering high radiation doses to coronary arteries to avoid or delay restenosis has been suggested. Known as intravascular brachytherapy, the technique has been used with several radiation sources, and researchers have obtained success in decreasing the rate of restenosis in some patient populations. In order to study the radiation dosimetry in the patient and radiological protection for the attending staff for this therapy, radiation dose distributions for monoenergetic electrons and photons (at nine discrete energies) were calculated for blood vessels of diameter 0.15, o,30 and 0.45 cm with balloon and wire sources using the radiation transport code MCNP4B. Specific calculations were carried out for several candidate radionuclides as well. Two s tent sources (metallic prosthesis that put inside of patient's artery through angioplasty) employing 32 P are also simulated. Advantages and disadvantages of the various radionuclides and source geometries are discussed. The dosimetry developed here will aid in the realization of the benefits obtained in patients for this promising new technology. (author)

  3. Quantificação volumétrica da hiperplasia neointimal em artérias ilíacas após implante de suporte intravascular metálico Volumetric assessment of neointimal hyperplasia in iliac arteries after metal stent implantation

    Directory of Open Access Journals (Sweden)

    Samuel Martins Moreira

    2009-08-01

    Full Text Available OBJETIVO: Quantificar a hiperplasia neointimal em artérias ilíacas após stent, correlacionando fatores clínicos, arteriais e materiais dos stents. MATERIAIS E MÉTODOS: De junho de 2003 a agosto de 2005, 60 pacientes realizaram angioplastia transluminal percutânea e stent. Desses, 30 foram reestudados com ultrassonografia intravascular. Os dados foram analisados no laboratório de análise quantitativa. RESULTA-DOS: Dezesseis pacientes eram do sexo masculino (53,3% e 14 (46,7%, do sexo feminino. A média de idade foi de 60,3 anos. Apresentaram hipertensão arterial 22 pacientes (73,3%, tabagismo, 18 (62,1%, hiperlipidemia, 20 (66,7%, e diabetes, 9 (30%. Foram implantados 20 stents de nitinol (66,7% e 10 de aço inoxidável (33,3%. Quatro pacientes eram TASC A (13,3%, 15 eram TASC B (50% e 11, TASC C (36,7%. O volume da hiperplasia variou de 49,02 mm³ a 112,87 mm³ (média de 80,33 mm³. O percentual de obstrução intra-stent variou de 18% a 47% (média de 27,4%. Os resultados clínicos obtidos com stent se mantiveram até o reestudo. CONCLUSÃO: A hiperplasia neointimal sempre ocorre após a angioplastia transluminal percutânea e stent, porém os percentuais de obstrução não foram superiores a 50% em nenhum caso. Não houve diferença estatisticamente significante dos percentuais de obstrução intra-stent quanto aos materiais dos stents, aos fatores clínicos e aos fatores arteriais.OBJECTIVE: To quantify neointimal hyperplasia in iliac arteries after stent implantation, correlating clinical, arterial factors and stent material. MATERIALS AND METHODS: In the period from June/2003 to August/ 2005, 60 patients were submitted to percutaneous transluminal angioplasty and stenting. Among these patients, 30 were followed-up with intravascular ultrasonography. Data were analyzed in a laboratory of quantitative analysis by means of a specific software. RESULTS: Sixteen (53.3% patients were men, and 14 (46.7%, women, and the mean age was 60

  4. Intravascular ultrasound assessed incomplete stent apposition and stent fracture in stent thrombosis after bare metal versus drug-eluting stent treatment the Nordic Intravascular Ultrasound Study (NIVUS)

    DEFF Research Database (Denmark)

    Kosonen, Petteri; Vikman, Saila; Jensen, Lisette Okkels

    2012-01-01

    This prospective multicenter registry used intravascular ultrasound (IVUS) in patients with definite stent thrombosis (ST) to compare rates of incomplete stent apposition (ISA), stent fracture and stent expansion in patients treated with drug-eluting (DES) versus bare metal (BMS) stents. ST...... is a rare, but potential life threatening event after coronary stent implantation. The etiology seems to be multifactorial....

  5. Infecções em dispositivos neurológicos implantáveis em crianças e adolescentes Ventriculoperitoneal shunt infections in children and adolescents with hydrocephalus

    Directory of Open Access Journals (Sweden)

    Márcia Maria Macêdo Lima

    2007-03-01

    Full Text Available OBJETIVO: Determinar a freqüência, as causas, o sítio específico e as manifestações clínicas e laboratoriais das infecções em crianças e adolescentes após a implantação de dispositivos neurológicos (DVP no Hospital Governador João Alves Filho (Aracaju SE. MÉTODO: Estudo prospectivo, observacional, não controlado de 50 pacientes, submetidos a DVP (58 procedimentos, no período de janeiro de 2003 a outubro de 2004. RESULTADOS: Observaram-se taxas de infecção por procedimento de 27,6%, taxas de infecção de índice cirúrgico zero, 1 e 2 de 25,7% e 30,4%, respectivamente (NNIS-CDC. A infecção de sítio cirúrgico foi a principal complicação com 50% das infecções. CONCLUSÃO: Taxa de infecção por procedimento, paciente e índice de risco cirúrgico mostraram-se elevadas. Não houve significância estatística com relação à idade, etiologia da hidrocefalia, ao tipo de procedimento (derivação primária e reinserção, tempo de internação pré-operatória, duração da cirurgia, antibioticoprofilaxia, cateter SNC prévio e índice de risco cirúrgico.OBJECTIVE: To determine frequency, etiology, site and clinical and laboratory findings of ventriculoperitoneal shunt (VPS infections in children and adolescents with hydrocephalus managed in Hospital Governador João Alves Filho, Aracaju SE, Brazil. METHOD: A non-controlled prospective observational study comprising 50 patients that underwent VPS (58 procedures from January/2003 to October/2004. RESULTS: Infection rate per procedure was 27.6%; surgical risk index (NNISS-CDC 0 and 1-2 were 25.7% and 30.4% respectively; surgical site infection was the main complication with 50% of the cases. CONCLUSION: Infection rates per procedure, per patient, and per surgical risk index were high. No statistical differences were found related to the following: age, etiology of hydrocephalus, type of procedure, pre-operative length of stay, duration of procedure, antibiotic prophylaxis

  6. Intravascular bronchio-alveolar tumor

    International Nuclear Information System (INIS)

    Mata, J.M.; Caceres, J.; Prat, J.; Lopez, J.I.; Velilla, O.

    1991-01-01

    In 1975 Dail and Liebow described the clinical and pathological characteristics of a pulmonary tumor which they dominated intravascular bronchio-alveolar tumor (IVBAT). Our aim is to acquaint radiologists with the existence of this tumor by describing the radiologic findings in 2 patients with IVBAT, 1 with hepatic involvement ant the other with pulmonary osteoarthropathy. (author). 7 refs.; 2 figs

  7. 150. ¿Tres en uno? Implante de tres dispositivos de asistencia circulatoria a un mismo paciente como terapia pre y postrasplante cardíaco. A propósito de un caso

    Directory of Open Access Journals (Sweden)

    J.A. Fernández-Divar

    2012-04-01

    Conclusiones: El implante ECMO es rápido y seguro, y permite mantener con vida a pacientes en shock cardiogénico grave. La reconversión a asistencias de media duración nos ayuda a mejorar el estado del paciente y que éste llegue al trasplante cardíaco en mejores condiciones. La incorporación de asistencias en pacientes con fallo primario del injerto (FPI tras el trasplante supone un avance en el tratamiento de esta patología.

  8. Renal Sympathetic Denervation System via Intraluminal Ultrasonic Ablation: Therapeutic Intravascular Ultrasound Design and Preclinical Evaluation.

    Science.gov (United States)

    Chernin, Gil; Szwarcfiter, Iris; Bausback, Yvonne; Jonas, Michael

    2017-05-01

    To assess the safety and performance of a nonfocused and nonballooned ultrasonic (US) catheter-based renal sympathetic denervation (RDN) system in normotensive swine. RDN with the therapeutic intravascular US catheter was evaluated in 3 experiments: (i) therapeutic intravascular US RDN vs a control group of untreated animals with follow-up of 30, 45, and 90 days (n = 6; n = 12 renal arteries for each group); (ii) therapeutic intravascular US RDN vs radiofrequency (RF) RDN in the contralateral artery in the same animal (n = 2; n = 4 renal arteries); and (iii) therapeutic intravascular US RDN in a recently stent-implanted renal artery (n = 2; n = 4 renal arteries). In the first experiment, therapeutic intravascular US RDN was safe, without angiographic evidence of dissection or renal artery stenosis. Neuronal tissue vacuolization, nuclei pyknosis, and perineuronal inflammation were evident after RDN, without renal artery wall damage. Norepinephrine levels were significantly lower after therapeutic intravascular US RDN after 30, 45, and 90 days compared with the control group (200.17 pg/mg ± 63.35, 184.75 pg/mg ± 44.51, and 203.43 pg/mg ± 58.54, respectively, vs 342.42 pg/mg ± 79.97). In the second experiment, deeper neuronal ablation penetrance was found with therapeutic intravascular US RDN vs RF RDN (maximal penetrance from endothelium of 7.0 mm vs 3.5 mm, respectively). There was less damage to the artery wall after therapeutic intravascular US RDN than with RF RDN, after which edema and injured endothelium were seen. In the third experiment, denervation inside the stent-implanted segments was feasible without damage to the renal artery wall or stent. The therapeutic intravascular US system performed safely and reduced norepinephrine levels. Deeper penetrance and better preservation of vessel wall were observed with therapeutic intravascular US RDN vs RF RDN. Neuronal ablations were observed in stent-implanted renal arteries. Copyright © 2017 SIR. Published

  9. Head to head comparison of optical coherence tomography, intravascular ultrasound echogenicity and virtual histology for the detection of changes in polymeric struts over time

    DEFF Research Database (Denmark)

    Brugaletta, Salvatore; Gomez-Lara, Josep; Bruining, Nico

    2012-01-01

    To analyse and to compare the changes in the various optical coherence tomography (OCT), echogenicity and intravascular ultrasound virtual histology (VH) of the everolimus-eluting bioresorbable scaffold (ABSORB) degradation parameters during the first 12 months after ABSORB implantation. In the A......To analyse and to compare the changes in the various optical coherence tomography (OCT), echogenicity and intravascular ultrasound virtual histology (VH) of the everolimus-eluting bioresorbable scaffold (ABSORB) degradation parameters during the first 12 months after ABSORB implantation...

  10. 21 CFR 880.5200 - Intravascular catheter.

    Science.gov (United States)

    2010-04-01

    ... Devices § 880.5200 Intravascular catheter. (a) Identification. An intravascular catheter is a device that consists of a slender tube and any necessary connecting fittings and that is inserted into the patient's vascular system for short term use (less than 30 days) to sample blood, monitor blood pressure, or...

  11. Dosimetric model for intravascular brachytherapy

    International Nuclear Information System (INIS)

    Flower, E.E.; Stroud, D.B.

    2000-01-01

    Full text: Intravascular brachytherapy has been shown to be a prophylaxis for restenosis. Adventitial macrophages, which are extremely radiosensitive, initiate neointima formation. A model of the dose levels of the treatment range is developed, assuming that the adventitia is the target tissue. If the adventitia receives a dose of less than 10 Gy, it is assumed the treatment will be ineffective. If the dose to any part of the wall is above 30 Gy, it is assumed that the treatment could be detrimental. Hence the treatment range is between 10 and 30 Gy, with 20 Gy being the optimum dosage to the adventitia. An algorithm using numerical integration of published dose kernels calculates the dose at any point surrounding a beta ( 32 P) line source of finite length. Dose profiles were obtained to demonstrate edge effects. For long lesions, the source is often stepped along the artery. Dose changes due to separation or overlapping of sources during source stepping procedures were also determined. Isodose curves were superimposed on intravascular ultrasound images to demonstrate dose levels. For an exposure time of 60 seconds with a 200mCi source, the optimum dose of 20 Gy occurs at a distance 1.94mm from the centre of the source. The upper limit of the treatment dose range (30 Gy) occurs at 1.59mm. The lower limit of the treatment dose range (10 Gy) occurs at 2.7mm. Significant perturbations to the treatment dose range can be caused by non-centering of the source, edge effects and separation or overlapping of sources in stepping procedures. Despite these concerns, many successful procedures have been reported and this implies that the model is over simplified and requires modifications. Copyright (2000) Australasian College of Physical Scientists and Engineers in Medicine

  12. El dispositivo Problemática ambiental

    OpenAIRE

    Federico Di Pasquo; Tomas Busan; Gabriela Klier

    2018-01-01

    Se presenta y problematiza un dispositivo dirigido al tema de la problemática ambiental, del cual destaca su alcance global, su carácter de urgente y su capacidad para afectar a la viabilidad de la especie humana. A la vez, indicamos que esta caracterización de la crisis ambiental se encuentra asociada a una red institucional de corte internacional dirigida a la gestión de este tema. También, se señalan algunos intentos por utilizar a la problemática ambiental como coartada para el establecim...

  13. Hemi-Intravascular Stenting for Supermicrosurgical Anastomosis

    OpenAIRE

    Kensuke Tashiro, MD; Shuji Yamashita, MD; Mitsunaga Narushima, MD; Isao Koshima, MD; Shimpei Miyamoto, MD

    2017-01-01

    Background:. Although supermicrosurgical anastomosis is a widely known reconstructive microsurgical technique, it is difficult to perform. To expand the clinical use of supermicrosurgery, we used hemi-intravascular stenting (hemi-IVaS), which is performed by inserting an intravascular stent into one side of the vessel. We conducted lymphaticovenular anastomosis, free perforator flap transfer, and fingertip replantation with supermicrosurgical anastomosis using hemi-IVaS technique and examined...

  14. DISPOSITIVO DAS DROGAS E GOVERNO DA VIDA

    Directory of Open Access Journals (Sweden)

    Wanderson Vilton Silva

    Full Text Available Resumo Na perspectiva da Psicologia Social em diálogo com as teorizações de Michel Foucault e Giorgio Agamben, o objetivo deste artigo é problematizar de que maneira as drogas são constituídas como explicação para assassinatos de moradores de rua, construindo práticas e discursos relacionados ao governo da vida e da morte nas cidades. O material que apresentamos consiste em textos midiáticos e documentos públicos elaborados entre julho de 2010 e novembro de 2012 abordando tais assassinatos. Analisamos como o dispositivo das drogas formula uma ambiguidade e uma complexidade importantes para o governo dos moradores de rua a partir da construção de oposições: criminoso ou em situação de vulnerabilidade social. Procuramos contribuir criticamente com políticas públicas que visem os diversos modos de existir na cidade, pensar os espaços urbanos, os modos de governo e os processos de subjetivação, considerando a análise da ambiguidade e da complexidade produzidas em torno do dispositivo das drogas.

  15. Interventional and intravascular MR angiography

    International Nuclear Information System (INIS)

    Ladd, M.E.; Debatin, J.F.

    2000-01-01

    Magnetic resonance imaging (MRI) has a number of characteristics which make it attractive for guidance of intravascular therapeutic procedures, including high soft tissue contrast, imaging in any arbitrary oblique plane, lack of ionizing radiation, and the ability to provide functional information, such as flow velocity and volume per unit time. For MR guidance of vascular interventions to be safe, catheters and guidewires must be visualized relative to the vascular system and surrounding tissues. A number of approaches for making instruments visible in an MR environment are presented, including both passive and active techniques. Passive techniques depend on contrast agents or susceptibility artifacts, whereas active techniques, including MR tracking, MR profiling, and active field inhomogeneity, use some form of electrical coil built into the instrument. The potential for obtaining high-resolution images of the vessel wall using coils built into a catheter is also discussed. These images provide the capability to distinguish and identify various plaque components. The additional capabilities of MRI could potentially open up new applications beyond those currently performed under X-ray fluoroscopic guidance. (orig.) [de

  16. Coagulación intravascular diseminada = Disseminated intravascular coagulation

    Directory of Open Access Journals (Sweden)

    Arango Barrientos, Marcos

    2010-12-01

    Full Text Available La coagulación intravascular diseminada (CID es una entidad clínica frecuente que se presenta como fenómeno secundario a diversas enfermedades entre las cuales se destacan las infecciones graves, las neoplasias y las catástrofes obstétricas. Se caracteriza por una activación difusa y simultánea de los sistemas endógenos de la coagulación y la fibrinólisis. El depósito de pequeños trombos en la circulación conduce finalmente a disfunción orgánica múltiple y en algunos casos a la muerte. Las manifestaciones clínicas pueden incluir fenómenos trombóticos y hemorrágicos. Se ha propuesto un puntaje de fácil aplicación para simplificar el diagnóstico de la entidad. El tratamiento incluye el control específico de la causa subyacente que favorece la aparición de la CID, el soporte con hemoderivados en pacientes con manifestaciones de sangrado y la anticoagulación terapéutica en pacientes con trombosis mayores. El desarrollo de CID es un factor pronóstico adverso que aumenta significativamente la tasa de mortalidad. En este artículo de revisión se incluyen los siguientes aspectos de la CID: historia, epidemiología, clasificación, entidades asociadas, fisiopatología, clínica, diagnóstico, tratamiento y pronóstico.

  17. Dosimetry in intravascular brachytherapy; Calculos dosimetricos em braquiterapia intravascular

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Laelia Pumilla Botelho

    2000-03-01

    Among the cardiovascular diseases responsible for deaths in the adult population in almost all countries of the world, the most common is acute myocardial infarction, which generally occurs because of the occlusion of one or more coronary arteries. Several diagnostic techniques and therapies are being tested for the treatment of coronary artery disease. Balloon angioplasty has been a popular treatment which is less invasive than traditional surgeries involving revascularization of the myocardium, thus promising a better quality of life for patients. Unfortunately, the rate of restenosis (re-closing of the vessel) after balloon angioplasty is high (approximately 30-50% within the first year after treatment).Recently, the idea of delivering high radiation doses to coronary arteries to avoid or delay restenosis has been suggested. Known as intravascular brachytherapy, the technique has been used with several radiation sources, and researchers have obtained success in decreasing the rate of restenosis in some patient populations. In order to study the radiation dosimetry in the patient and radiological protection for the attending staff for this therapy, radiation dose distributions for monoenergetic electrons and photons (at nine discrete energies) were calculated for blood vessels of diameter 0.15, o,30 and 0.45 cm with balloon and wire sources using the radiation transport code MCNP4B. Specific calculations were carried out for several candidate radionuclides as well. Two s tent sources (metallic prosthesis that put inside of patient's artery through angioplasty) employing {sup 32} P are also simulated. Advantages and disadvantages of the various radionuclides and source geometries are discussed. The dosimetry developed here will aid in the realization of the benefits obtained in patients for this promising new technology. (author)

  18. Dosimetry in intravascular brachytherapy; Calculos dosimetricos em braquiterapia intravascular

    Energy Technology Data Exchange (ETDEWEB)

    Campos, Laelia Pumilla Botelho

    2000-03-01

    Among the cardiovascular diseases responsible for deaths in the adult population in almost all countries of the world, the most common is acute myocardial infarction, which generally occurs because of the occlusion of one or more coronary arteries. Several diagnostic techniques and therapies are being tested for the treatment of coronary artery disease. Balloon angioplasty has been a popular treatment which is less invasive than traditional surgeries involving revascularization of the myocardium, thus promising a better quality of life for patients. Unfortunately, the rate of restenosis (re-closing of the vessel) after balloon angioplasty is high (approximately 30-50% within the first year after treatment).Recently, the idea of delivering high radiation doses to coronary arteries to avoid or delay restenosis has been suggested. Known as intravascular brachytherapy, the technique has been used with several radiation sources, and researchers have obtained success in decreasing the rate of restenosis in some patient populations. In order to study the radiation dosimetry in the patient and radiological protection for the attending staff for this therapy, radiation dose distributions for monoenergetic electrons and photons (at nine discrete energies) were calculated for blood vessels of diameter 0.15, o,30 and 0.45 cm with balloon and wire sources using the radiation transport code MCNP4B. Specific calculations were carried out for several candidate radionuclides as well. Two s tent sources (metallic prosthesis that put inside of patient's artery through angioplasty) employing {sup 32} P are also simulated. Advantages and disadvantages of the various radionuclides and source geometries are discussed. The dosimetry developed here will aid in the realization of the benefits obtained in patients for this promising new technology. (author)

  19. Intravascular brachytherapy for peripheral vascular disease

    Directory of Open Access Journals (Sweden)

    Hagen, Anja

    2008-09-01

    Full Text Available Scientific background: Percutaneous transluminal angioplasties (PTA through balloon dilatation with or without stenting, i.e. vessel expansion through balloons with or without of implantation of small tubes, called stents, are used in the treatment of peripheral artery occlusive disease (PAOD. The intravascular vessel irradiation, called intravascular brachytherapy, promises a reduction in the rate of repeated stenosis (rate of restenosis after PTA. Research questions: The evaluation addresses questions on medical efficacy, cost-effectiveness as well as ethic, social and legal implications in the use of brachytherapy in PAOD patients. Methods: A systematic literature search was conducted in August 2007 in the most important medical electronic databases for publications beginning from 2002. The medical evaluation included randomized controlled trials (RCT. The information synthesis was performed using meta-analysis. Health economic modeling was performed with clinical assumptions derived from the meta-analysis and economical assumptions derived from the German Diagnosis Related Groups (G-DRG-2007. Results: Medical evaluation: Twelve publications about seven RCT on brachytherapy vs. no brachytherapy were included in the medical evaluation. Two RCT showed a significant reduction in the rate of restenosis at six and/or twelve months for brachytherapy vs. no brachytherapy after successful balloon dilatation, the relative risk in the meta-analysis was 0.62 (95% CI: 0.46 to 0.84. At five years, time to recurrence of restenosis was significantly delayed after brachytherapy. One RCT showed a significant reduction in the rate of restenosis at six months for brachytherapy vs. no brachytherapy after PTA with optional stenting, the relative risk in the meta-analysis was 0.76 (95% CI: 0.61 to 0.95. One RCT observed a significantly higher rate of late thrombotic occlusions after brachytherapy in the subgroup of stented patients. A single RCT for brachytherapy

  20. Novel approaches to the management of disseminated intravascular coagulation

    NARCIS (Netherlands)

    Levi, M. [=Marcel M.; de Jonge, E.; van der Poll, T.; ten Cate, H.

    2000-01-01

    Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic intravascular activation of coagulation, leading to widespread deposition of fibrin in the circulation. We addressed the issue of whether there is evidence that this fibrin deposition contributes to multiple organ

  1. Fluorescent Method for Observing Intravascular Bonghan Duct

    Directory of Open Access Journals (Sweden)

    Byung-Cheon Lee

    2005-12-01

    Full Text Available Observation of intra-vascular threadlike structures in the blood vessels of rats is reported with the images by differential interference contrast microscope, and fluorescence inverted microscope of the acridine-orange stained samples. The confocal microscope image and the hematoxylin-eosin staining revealed the distinctive pattern of nuclei distribution that clearly discerned the threadlike structure from fibrin, capillary, small venule, arteriole, or lymph vessel. Physiological function of the intra-vascular thread in connection with acupuncture is discussed. Especially, this threadlike duct can be a circulation path for herb-liquid flow, which may provide the scientific mechanism for therapeutic effect of herbal acupuncture.

  2. Desarrollo de un videojuego para dispositivos móviles

    OpenAIRE

    Ruiz Pérez, Francisco

    2016-01-01

    Los dispositivos móviles se han convertido en una de las principales plataformas para videojuegos. Una de las principales problemáticas al desarrollar aplicaciones para estos dispositivos es la alta fragmentación que existe en cuanto a sistemas operativos y características de la interfaz. Existen determinadas librerías y motores, tanto nativas como multiplataforma, dirigidas a resolver este problema.

  3. Evaluation of CT virtual intravascular endoscopy in fenestrated stent grafts: a preliminary study

    International Nuclear Information System (INIS)

    Sun, Z.; Allen, Y.; Fitzsimmons, B.; Hartely, D.; Lawrence-Brown, M.

    2007-01-01

    We aim in this study to investigate the potential value of CT virtual intravascular endoscopy in patients diagnosed with abdominal aortic aneurysms undergoing fenestrated stent grafts. Both pre-and post-fenestration (within 3 months of implantation) multislice CT data were collected in eight patients and used for generation of virtual endoscopy images in our preliminary study. Variable fenestrations were deployed in 25 aortic branches with scallop fenestration implanted in six aortic ostia, large fenestration in four aortic ostia and small fenestration in 15 renal ostia, respectively. Measurements of the aortic ostia diameters both pre- and post-fenestration were successfully performed with virtual intravascular endoscopy visualization, and endovascular stents as well as their relationship to the aortic ostia were clearly demonstrated. Our results showed that there was no significant change of diameter of the aortic ostia following fenestrated stem grafts. Endovascular stents were clearly visualized on virtual endoscopy images, and no apparent deformity or malrotation was observed in this small group. Our preliminary study provides new insights into anatomic configuration/dimension of aortic ostia and endovascular stents, and virtual intravascular endoscopy could be a valuable technique to follow-up patients treated with fenestrated stent grafts. (orig.)

  4. Evaluation of CT virtual intravascular endoscopy in fenestrated stent grafts: a preliminary study

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Z. [Dept. of Imaging and Applied Physics, Curtin Univ. of Tech., Perth, WA (Australia); Allen, Y.; Fitzsimmons, B.; Hartely, D. [Cook R and D, WA (Australia); Lawrence-Brown, M. [Dept. of Public Health, Curtin Univ. of Tech., Perth, WA (Australia)

    2007-06-15

    We aim in this study to investigate the potential value of CT virtual intravascular endoscopy in patients diagnosed with abdominal aortic aneurysms undergoing fenestrated stent grafts. Both pre-and post-fenestration (within 3 months of implantation) multislice CT data were collected in eight patients and used for generation of virtual endoscopy images in our preliminary study. Variable fenestrations were deployed in 25 aortic branches with scallop fenestration implanted in six aortic ostia, large fenestration in four aortic ostia and small fenestration in 15 renal ostia, respectively. Measurements of the aortic ostia diameters both pre- and post-fenestration were successfully performed with virtual intravascular endoscopy visualization, and endovascular stents as well as their relationship to the aortic ostia were clearly demonstrated. Our results showed that there was no significant change of diameter of the aortic ostia following fenestrated stem grafts. Endovascular stents were clearly visualized on virtual endoscopy images, and no apparent deformity or malrotation was observed in this small group. Our preliminary study provides new insights into anatomic configuration/dimension of aortic ostia and endovascular stents, and virtual intravascular endoscopy could be a valuable technique to follow-up patients treated with fenestrated stent grafts. (orig.)

  5. Quinine-induced disseminated intravascular coagulation.

    Science.gov (United States)

    Spearing, R L; Hickton, C M; Sizeland, P; Hannah, A; Bailey, R R

    Recurrent disseminated intravascular coagulation occurred in 3 women after ingestion of quinine tablets for cramp. All had circulating quinine-dependent antibodies to platelets and in 2 there was initial evidence of antibody consumption, with low titres that rose steeply over the next few days and remained high for many months.

  6. Intravascular volume after aneurysmal subarachnoid hemorrhage

    NARCIS (Netherlands)

    Hoff, R.G.

    2009-01-01

    Intravascular volume after aneurysmal subarachnoid hemorrhage A subarachnoid hemorrhage (SAH) from a ruptured cerebral aneurysm is a devastating disorder with an often poor prognosis. The occurrence of delayed cerebral ischemia (DCI) is one of the most important factors determining outcome in

  7. Disseminated Intravascular Coagulation Following Induction of ...

    African Journals Online (AJOL)

    Background: Disseminated Intravascular coagulopathy (DIC) has been reported following use of Misoprostol which is an old drug with new indications in Obstetrics and. Gynecology. Its effectiveness, low cost, stability in tropical conditions and ease of administration as well as side effects like gastrointestinal effect, uterine ...

  8. Hemi-Intravascular Stenting for Supermicrosurgical Anastomosis

    Directory of Open Access Journals (Sweden)

    Kensuke Tashiro, MD

    2017-11-01

    Conclusions:. Hemi-IVaS could be a useful alternative to conventional intravascular stenting techniques and is also effective for supermicrosurgical perforator-to-perforator anastomosis. Further studies are needed to improve the success rate and to explore its other possible utilizations in supermicrosurgery.

  9. Application of intravascular ultrasound in percutaneous coronary interventional therapy

    International Nuclear Information System (INIS)

    Wang Jingping; Li Bao; An Jian; Yang Bin; Wang Zhongchao; Wang Rijun; Zhang Wutang; Lei Xinyu; Wang Huixian; Lu Lifang; Gao Yongli

    2009-01-01

    Objective: To evaluate intravascular ultrasound (IVUS)in demonstrating the characteristics of coronary plaque and in implanting the coronary stent. Methods: Before stent implantation, IVUS was used to observe the plaque character/sties(soft, fibrotic, calcified or mixed) as well as the eccentric degree in 28 patients with angiographically-proved single coronary branch lesion. The minimal luminal diameter, minimal cross-sectional area and plaque area were measured. After stent deployment the above measurements were repeated, and the location, symmetrical index and expansion of the stent were observed. Results: A total of 36 stents was implanted in 28 patients with coronary disease. After the procedure the minimal luminal diameter and the minimal cross-sectional area was increased, while the plaque area was decreased. The difference between the values before and after the stent implantation was statistically significant (P<0.01). IVUS after stent deployment found that in all cases the stent had a nice location and covered the lesion completely with no interlayer at its both ends. Excellent expansion of the stent was seen in 30 cases (83.3%). Insufficient expansion occurred in 3 cases and undesirable contact of the stent to the arterial wall was found in 3 cases (16.7%). In such circumstances, one size bigger low-compliance balloon dilatation was adopted, or the original balloon was used again with higher pressure (18-22 atm), in order to expand the stent once more, and good results accord with IVUS optimal criteria were obtained. Conclusions: IVUS can clearly demonstrate the pathological features of the coronary lesions, such as plaque type, eccentric degree, luminal diameter, cross-sectional area and plaque area, which are very helpful in guiding the selection of the proper stent before the procedure, and are also very useful in evaluating the location, expansion of the stent as well as the stent-to-wall contact condition after the procedure. (authors)

  10. Mapping intravascular ultrasound controversies in interventional cardiology practice.

    Directory of Open Access Journals (Sweden)

    David Maresca

    Full Text Available Intravascular ultrasound is a catheter-based imaging modality that was developed to investigate the condition of coronary arteries and assess the vulnerability of coronary atherosclerotic plaques in particular. Since its introduction in the clinic 20 years ago, use of intravascular ultrasound innovation has been relatively limited. Intravascular ultrasound remains a niche technology; its clinical practice did not vastly expand, except in Japan, where intravascular ultrasound is an appraised tool for guiding percutaneous coronary interventions. In this qualitative research study, we follow scholarship on the sociology of innovation in exploring both the current adoption practices and perspectives on the future of intravascular ultrasound. We conducted a survey of biomedical experts with experience in the technology, the practice, and the commercialization of intravascular ultrasound. The collected information enabled us to map intravascular ultrasound controversies as well as to outline the dynamics of the international network of experts that generates intravascular ultrasound innovations and uses intravascular ultrasound technologies. While the technology is praised for its capacity to measure coronary atherosclerotic plaque morphology and is steadily used in clinical research, the lack of demonstrated benefits of intravascular ultrasound guided coronary interventions emerges as the strongest factor that prevents its expansion. Furthermore, most of the controversies identified were external to intravascular ultrasound technology itself, meaning that decision making at the industrial, financial and regulatory levels are likely to determine the future of intravascular ultrasound. In light of opinions from the responding experts', a wider adoption of intravascular ultrasound as a stand-alone imaging modality seems rather uncertain, but the appeal for this technology may be renewed by improving image quality and through combination with

  11. Techniques for Intravascular Foreign Body Retrieval

    International Nuclear Information System (INIS)

    Woodhouse, Joe B.; Uberoi, Raman

    2013-01-01

    As endovascular therapies increase in frequency, the incidence of lost or embolized foreign bodies is increasing. The presence of an intravascular foreign body (IFB) is well recognized to have the potential to cause serious complications. IFB can embolize and impact critical sites such as the heart, with subsequent significant morbidity or mortality. Intravascular foreign bodies most commonly result from embolized central line fragments, but they can originate from many sources, both iatrogenic and noniatrogenic. The percutaneous approach in removing an IFB is widely perceived as the best way to retrieve endovascular foreign bodies. This minimally invasive approach has a high success rate with a low associated morbidity, and it avoids the complications related to open surgical approaches. We examined the characteristics, causes, and incidence of endovascular embolizations and reviewed the various described techniques that have been used to facilitate subsequent explantation of such materials

  12. Intravascular photoacoustic imaging of human coronary atherosclerosis

    Science.gov (United States)

    Jansen, Krista; van der Steen, Antonius F. W.; Springeling, Geert; van Beusekom, Heleen M. M.; Oosterhuis, J. Wolter; van Soest, Gijs

    2011-03-01

    We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. We specifically imaged lipid content, a key factor in vulnerable plaques that may lead to myocardial infarction. An integrated intravascular photoacoustics (IVPA) and ultrasound (IVUS) catheter with an outer diameter of 1.25 mm was developed. The catheter comprises an angle-polished optical fiber adjacent to a 30 MHz single-element transducer. The ultrasonic transducer was optically isolated to eliminate artifacts in the PA image. We performed measurements on a cylindrical vessel phantom and isolated point targets to demonstrate its imaging performance. Axial and lateral point spread function widths were 110 μm and 550 μm, respectively, for PA and 89 μm and 420 μm for US. We imaged two fresh human coronary arteries, showing different stages of disease, ex vivo. Specific photoacoustic imaging of lipid content, is achieved by spectroscopic imaging at different wavelengths between 1180 and 1230 nm.

  13. Fluorescent Method for Observing Intravascular Bonghan Duct

    OpenAIRE

    Byung-Cheon Lee; Ku Youn Baik; Hyeon-Min Johng; Baekkyoung Sung; Kyung Soon Soh; Dae-In Kang; Kwang-Sup Soh

    2005-01-01

    Observation of intra-vascular threadlike structures in the blood vessels of rats is reported with the images by differential interference contrast microscope, and fluorescence inverted microscope of the acridine-orange stained samples. The confocal microscope image and the hematoxylin-eosin staining revealed the distinctive pattern of nuclei distribution that clearly discerned the threadlike structure from fibrin, capillary, small venule, arteriole, or lymph vessel. Physiological function of ...

  14. Heterogeneous Intravascular Ultrasound Findings of Stent Thrombosis

    OpenAIRE

    Morofuji, Toru; Inaba, Shinji; Aisu, Hiroe; Takahashi, Kayo; Saito, Makoto; Higashi, Haruhiko; Yoshii, Toyofumi; Sumimoto, Takumi

    2017-01-01

    Objective The underlying mechanisms of stent thrombosis are not completely understood. Methods We experienced 12 definite stent thrombosis cases (1 early, 1 late, and 10 very late) at our hospital from July 2011 to April 2016 and evaluated the possible causes of stent thrombosis by intravascular ultrasound (IVUS). Results Five different potential morphological causes of stent thrombosis (neoatherosclerosis, stent malapposition, stent fracture, edge dissection, and stent underexpansion) were d...

  15. Programación de controladores de dispositivos en Windows

    OpenAIRE

    Gutiérrez Peón, Pablo

    2013-01-01

    Este documento pretende servir como toma de contacto en la construcción de controladores de dispositivos para el sistema operativo Windows. Se repasa brevemente el entorno Windows para continuar con los componentes básicos en la realización de controladores. Para finalizar se da una pequeña guía con los pasos a seguir al desarrollar controladores de dispositivos. La información contenida en este documento procede del siguiente manual: Art Baker y Jerry Lozano. The Windows 2...

  16. Firma digital en dispositivos móviles PDA

    OpenAIRE

    Emanuel Curcio, Federico

    2007-01-01

    En los últimos tiempos, uno de los campos de mayor desarrollo en las tecnologías de la información es el de la seguridad criptográfica y, más concretamente, el de la firma digital. Al mismo tiempo, se ha hecho cada vez mas extendido el uso de los dispositivos móviles PDA. Estos dispositivos se han convertido en verdaderos ordenadores de bolsillo, con capacidades que prácticamente igualan las de sus pares de sobremesa o portátiles. Este proyecto surge de la idea de impl...

  17. Diseño e implementación de una plataforma hardware para un sistema de acceso inalámbrico a dispositivos médicos mediante Heart-To-Heart

    OpenAIRE

    López Asunción, Samuel

    2016-01-01

    En este Proyecto Fin de Carrera se ha desarrollado un sistema de acceso inalámbrico seguro a un dispositivo médico implantable, en nuestro caso un marcapasos, mediante un protocolo de acceso Heart-To-Heart. El objetivo es diseñar un sistema capaz de extraer datos de un paciente o reprogramar su dispositivo implantado con un control suficientemente estricto para evitar accesos no autorizados, pero lo suficientemente permisivo cuando ocurran situaciones de emergencia médica. El sistema dispondr...

  18. Hemi-Intravascular Stenting for Supermicrosurgical Anastomosis

    Science.gov (United States)

    Yamashita, Shuji; Narushima, Mitsunaga; Koshima, Isao; Miyamoto, Shimpei

    2017-01-01

    Background: Although supermicrosurgical anastomosis is a widely known reconstructive microsurgical technique, it is difficult to perform. To expand the clinical use of supermicrosurgery, we used hemi-intravascular stenting (hemi-IVaS), which is performed by inserting an intravascular stent into one side of the vessel. We conducted lymphaticovenular anastomosis, free perforator flap transfer, and fingertip replantation with supermicrosurgical anastomosis using hemi-IVaS technique and examined its usefulness. Methods: Between January 2013 and February 2015, 11 anastomoses in 11 cases of lymphaticovenular anastomosis for lymphedema patients, 14 anastomoses in 7 cases of free perforator flap transfer with supermicrosurgical perforator-to-perforator anastomosis, and 9 anastomoses in 5 cases of fingertip replantation were performed using hemi-IVaS. Time required for anastomosis and complications were examined. Flap survival rate was also examined in free perforator flap transfer cases and fingertip replantation cases. Results: In all cases, anastomoses were performed without complications such as inadvertent catching of the back wall of the vessel during the procedure or the need for reanastomoses. The average time required to complete the anastomosis was 16.4 ± 3.20 minutes using the hemi IVaS technique. All flaps survived in the supermicrosurgical perforator-to-perforator anastomosis as well as fingertip replantation cases. Conclusions: Hemi-IVaS could be a useful alternative to conventional intravascular stenting techniques and is also effective for supermicrosurgical perforator-to-perforator anastomosis. Further studies are needed to improve the success rate and to explore its other possible utilizations in supermicrosurgery. PMID:29263952

  19. Intravascular imaging with a storage phosphor detector

    Energy Technology Data Exchange (ETDEWEB)

    Shikhaliev, Polad M; Petrek, Peter; Matthews, Kenneth L II; Fritz, Shannon G [Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA (United States); Bujenovic, L Steven [PET Imaging Center, Our Lady of the Lake Medical Center, Baton Rouge, LA (United States); Xu Tong, E-mail: pshikhal@lsu.ed [Department of Physics, Carleton University, Ottawa (Canada)

    2010-05-21

    The aim of this study is to develop and test an intravascular positron imaging system based on a storage phosphor detector for imaging and detecting vulnerable plaques of human coronary arteries. The radiotracer F18-FDG accumulates in vulnerable plaques with inflammation of the overlying cap. The vulnerable plaques can, therefore, be imaged by recording positrons emitted from F18-FDG with a detector inserted into the artery. A prototype intravascular detector was constructed based on storage phosphor. The detector uses a flexible storage phosphor tube with 55 mm length, 2 mm diameter and 0.28 mm wall thickness. The intravascular detector is guided into the vessel using x-ray fluoroscopy and the accumulated x-ray signal must be erased prior to positron imaging. For this purpose, a light diffuser, 0.9 mm in diameter and 55 mm in length, was inserted into the detector tube. The light diffuser was connected to a laser source through a 2 m long optical fiber. The diffuser redirected the 0.38 W laser light to the inner surface of the phosphor detector to erase it. A heart phantom with 300 cm{sup 3} volume and three coronary arteries with 3.2 mm diameter and with several plaques was constructed. FDG solution with 0.5 {mu}Ci cm{sup -3} activity concentration was filled in the heart and coronary arteries. The detector was inserted in a coronary artery and the signal from the plaques and surrounding background activity was recorded for 2 min. Then the phosphor detector was extracted and read out using a storage phosphor reader. The light diffuser erased the signal resulting from fluoroscopic exposure to level below that encountered during positron imaging. Vulnerable plaques with area activities higher than 1.2 nCi mm{sup -2} were visualized by the detector. This activity is a factor of 10-20 lower than that expected in human vulnerable plaques. The detector was able to image the internal surface of the coronary vessels with 50 mm length and 360{sup 0} circumference. Spatial

  20. Mapping Intravascular Ultrasound Controversies in Interventional Cardiology Practice

    NARCIS (Netherlands)

    Maresca, D.; Adams, S.; Maresca, B.; Van der Steen, A.F.W.

    2014-01-01

    Intravascular ultrasound is a catheter-based imaging modality that was developed to investigate the condition of coronary arteries and assess the vulnerability of coronary atherosclerotic plaques in particular. Since its introduction in the clinic 20 years ago, use of intravascular ultrasound

  1. Role of informed consent for intravascular contrast media

    International Nuclear Information System (INIS)

    Hopper, K.D.; Tyler, H.N. Jr.

    1988-01-01

    To evaluate the usefulness of different degrees of informed consent for intravascular contrast media, the authors divided 100 patients into four groups: (1) informed consent with no information on intravascular contrast media, (2) simple written informed consent that detailed common risks, (3) detailed written informed consent that detailed all known risks, and (4) MD informed consent, during which a radiologist discussed all known risks of intravascular contrast media. Physician counseling time for group 4 averaged 11.4 minutes. On a postprocedure test about the common complications and risk factors of intravascular contrast media, the average scores were: group 1, 38.4%; group 2, 68.2%; group 3, 63.2%; and group 4, 69.8%. There was no statistical difference between groups 2-4 on the postprocedure test. If informed consent is to be used prior to intravascular contrast media administration, a simple written consent detailing the common risks and risk factors appears to be the best method

  2. 3D dosimetry study of 188Re liquid balloon for intravascular brachytherapy using BANG polymer gel dosemeters

    International Nuclear Information System (INIS)

    Wuu, S.; Schiff, P.B.; Maryanski, M.; Liu, T.; Borzillary, S.; Weinberger, J.

    2002-01-01

    It has been suggested that the combination of intravascular brachytherapy and coronary stent implantation may result in further reduction of restenosis after percutaneous balloon angioplasty. The use of an angioplasty balloon filled with a P 188 Re liquid beta source for intravascular brachytherapy provides the advantage of accurate source positioning and uniform dose distribution to the coronary vessel wall. The effect of source edge and stent on the dose distribution of the target tissue may be clinically important. In BANG gels, the absorbed radiation produces free-radical chain polymerisation of acrylic monomers that are initially dissolved in the gel. The number of polymer particles is proportional to the absorbed dose. In this study, 3D dose distributions are presented for 188 Re balloons, with and without stents, using a prototype He-Ne laser CT scanner and the proprietary BANG polymer gel dosemeters. (author)

  3. Ventricular metastasis resulting in disseminated intravascular coagulation

    Directory of Open Access Journals (Sweden)

    Davis Ian D

    2005-05-01

    Full Text Available Abstract Background Disseminated Intravascular Coagulation (DIC complicates up to 7% of malignancies, the commonest solid organ association being adenocarcinoma. Transitional Cell Carcinoma (TCC has rarely been associated with DIC. Case presentation A 74-year-old woman with TCC bladder and DIC was found to have a cardiac lesion suspicious for metastatic disease. The DIC improved with infusion of plasma and administration of Vitamin K, however the cardiac lesion was deemed inoperable and chemotherapy inappropriate; given the patients functional status. We postulate that direct activation of the coagulation cascade by the intraventricular metastasis probably triggered the coagulopathy in this patient. Conclusion Cardiac metastases should be considered in cancer patients with otherwise unexplained DIC. This may influence treatment choices.

  4. Death following intravascular administration of contrast media

    International Nuclear Information System (INIS)

    Shehadi, W.H.

    1985-01-01

    Adverse reactions to intravascularly administered contrast media preceding death and the autopsy findings in 44 patients are presented. There is a wide scatter of the age distribution of fatal reactions. The highest incidence is in the 50-70 year age group. Similar observations were obtained from the 405 deaths due to contrast media reported to the Food and Drug Administration of the United States. In the same age group the number of reactions is highest, likewise the autopsy findings. The predominant autopsy findings are pulmonary edema, congestion and hemorrhage; arteriosclerosis, both general and coronary. In the younger age group the autopsy findings are limited mostly to the respiratory tract. Fatal reactions to contrast media occur often without warning and most deaths occur within 15 min to 6 hours. Reactions to contrast media occur without relation to sex or age. (orig.)

  5. Guidelines for the diagnosis and management of disseminated intravascular coagulation

    NARCIS (Netherlands)

    Levi, M. [=Marcel M.; Toh, C. H.; Thachil, J.; Watson, H. G.

    2009-01-01

    The diagnosis of disseminated intravascular coagulation (DIC) should encompass both clinical and laboratory information. The International Society for Thrombosis and Haemostasis (ISTH) DIC scoring system provides objective measurement of DIC. Where DIC is present the scoring system correlates with

  6. Disseminated intravascular and intracardiac thrombosis after cardiopulmonary bypass

    Directory of Open Access Journals (Sweden)

    Deepak K Tempe

    2017-01-01

    Full Text Available Massive intracardiac and intravascular thrombosis is a rare complication following cardiopulmonary bypass (CPB. Most of the cases of the disseminated thrombosis have been reported in patients undergoing complex cardiac surgeries and those receiving antifibrinolytic agents during CPB. We report the occurrence of disseminated intravascular and intracardiac thrombosis after CPB in a patient undergoing mitral valve replacement in which no antifibrinolytic agent was used. The possible pathophysiology and management of the patient is discussed.

  7. Seguridad en dispositivos móviles: un enfoque práctico

    OpenAIRE

    Macia, Nicolás; Lanfranco, Einar Felipe; Venosa, Paula; Piazza Orlando, Carlos Damián; Pacheco Veliz, Sebastián Exequiel

    2014-01-01

    Hoy en día, los dispositivos móviles son un elemento común en la vida diaria de las personas. Los problemas de seguridad a los que estos dispositivos están expuestos son similares a los que esta expuesto una PC. Inclusive, se dan a otros problemas relacionados con el espionaje, puesto que un dispositivo comprometido podría permitir consultar su localización vía GPS, transmitir la información captada por su micrófono o incluso su cámara. El problema de la inseguridad en dichos dispositivos ...

  8. Intravascular Large B-Cell Lymphoma

    Directory of Open Access Journals (Sweden)

    Maria S. Khan MD, FACP

    2014-03-01

    Full Text Available Case Presentation . A 69-year-old Hispanic male, with a past history of diabetes and coronary disease, was admitted for fever, diarrhea, and confusion of 4 weeks duration. Physical examination showed a disoriented patient with multiple ecchymoses, possible ascites, and bilateral scrotal swelling. Hemoglobin was 6.7, prothrombin time (PT 21.4 seconds with international normalized ratio 2.1, partial thromboplastin time (PTT 55.6 seconds, fibrin split 10 µg/L, and lactate dehydrogenase (LDH 1231 IU/L. Except for a positive DNA test for Epstein–Barr virus (EBV infection, extensive diagnostic workup for infections, malignancy, or a neurological cause was negative. Mixing studies revealed a nonspecific inhibitor of PT and PTT but Factor VIII levels were normal. The patient was empirically treated with antibiotics but developed hypotension and died on day 27 of admission. At autopsy, patient was found to have intravascular diffuse large B-cell lymphoma involving skin, testes, lung, and muscles. The malignant cells were positive for CD20, CD791, Mum-1, and Pax-5 and negative for CD3, CD5, CD10, CD30, and Bcl-6. The malignant cells were 100% positive for Ki-67. Discussion . Intravascular large cell B-cell lymphoma (IVLBCL is rare form of diffuse large B-cell lymphoma and tends to proliferate within small blood vessels, particularly capillaries and postcapillary venules. The cause of its affinity for vascular bed remains unknown. In many reports, IVLBCL was associated with HIV, HHV8, and EBV infections. The fact that our case showed evidence of EBV infection lends support to the association of this diagnosis to viral illness. The available literature on this subject is scant, and in many cases, the diagnosis was made only at autopsy. The typical presentation of this disorder is with B symptoms, progressive neurologic deficits, and skin findings. Bone marrow, spleen, and liver are involved in a minority of patients. Nearly all patients have elevated LDH

  9. A quality management program in intravascular brachytherapy

    International Nuclear Information System (INIS)

    Chakri, Abderrahim; Thomadsen, Bruce

    2002-01-01

    While simple, intravascular brachytherapy (IVB) presents a considerable potential for harm to the patient. The medical physicist maintains the responsibility to minimize the likelihood of operational problems or dosimetric errors. The principals for safe operation remain the same as with any radiotherapy treatment: to deliver the correct dose, to the correct location, safety. To develop an effective and comprehensive quality management (QM) program for IVB, a physicist should utilize proven risk assessment techniques rather than simply thinking of things to check, and follow guidances such as ISO9001:2000. The proposed QM program includes the following: Procedures designed to assure the safety of the patient: Identification of the patient; tests of the integrity and patency for the delivery catheter, operation of the source train, and patency of the catheter in the treatment position; a check for recovery preparations; and verification of source recovery. Procedures to assure positional accuracy of the treatment: Verification of the positioning the catheter in the artery and of the sources in the catheter. Procedures to assure dosimetry accuracy: Acceptance testing of the device, including verification of the source strength and uniformity, and of the treatment duration tables; verification of the treatment prescription and duration for each patient; and control measures that minimize the likelihood of errors removing the source at the correct time

  10. Disseminated intravascular coagulation in solid tumors

    International Nuclear Information System (INIS)

    Terzieff, V.; Alonso, I.; Vázquez, A.

    2004-01-01

    It is estimated that 20-25% of cases of disseminated intravascular coagulation (DIC) relate to an underlying neoplasia primarily hematologic. It is estimated that about 5% of patients with solid tumors have CID clinic, although the incidence of subclinical alterations is much higher. The CID is not limited to the activation of the coagulation cascade, which leads to bleeding micro thrombosis and consumption of coagulation factors. Solid tumors are frequently associated adenocarcinomas producers mucin (especially gastric), usually in the context of a disseminated disease. The mucin may act as a promoter of the cascade, but probably it is a multi-event. High levels of TNF to produced by the tumor mass and chemotherapy-induced cell lysis have Also linked. Although the bleeding is usually oriented diagnosis, the most frequent cause of death is thrombosis. There are no specific tests for diagnosis. Elevated levels of D-dimer and products oriented fibrinogen degradation diagnosis. No reduction fibrinogen and almost always, one thrombocytopenia consumption. Treatment is complex and there is no consensus on many points. To recover the lost factors for consumption, it is recommended to use fresh frozen plasma and / or washed red blood cells. the heparin anticoagulation low dose is indicated since the disease causal can not be controlled quickly, but should not be initiated if there thrombocytopenia 50.000.El under profuse bleeding can require the use of tranexamic acid or EACA. Acute DIC, the case of our patient, is rare and very serious

  11. Uso de los sistemas de presión negativa en el tratamiento de infecciones asociadas a dispositivos: “una vieja terapia con un uso novedoso”

    OpenAIRE

    William Fernando Bautista Vargas; Diego Andrés Rodriguez Guerrero; Luis Carlos Sáenz

    2017-01-01

    Introducción: El cuidado de los pacientes con infecciones asociadas al dispositivo sin endocarditis, incluye: la extracción completa y la realización de capsulectomía para evitar la reinfección. El uso de nuevos elementos como el sistema de la presión negativa es una terapia novedosa que ha demostrado disminuir: los tiempos de recuperación, el tiempo de estancia intrahospitalaria, la necesidad de nuevas intervenciones por sangrado o lavado y el tiempo de espera para un nuevo implante. Nuestro...

  12. Rotational multispectral fluorescence lifetime imaging and intravascular ultrasound: bimodal system for intravascular applications

    Science.gov (United States)

    Ma, Dinglong; Bec, Julien; Yankelevich, Diego R.; Gorpas, Dimitris; Fatakdawala, Hussain; Marcu, Laura

    2014-01-01

    Abstract. We report the development and validation of a hybrid intravascular diagnostic system combining multispectral fluorescence lifetime imaging (FLIm) and intravascular ultrasound (IVUS) for cardiovascular imaging applications. A prototype FLIm system based on fluorescence pulse sampling technique providing information on artery biochemical composition was integrated with a commercial IVUS system providing information on artery morphology. A customized 3-Fr bimodal catheter combining a rotational side-view fiberoptic and a 40-MHz IVUS transducer was constructed for sequential helical scanning (rotation and pullback) of tubular structures. Validation of this bimodal approach was conducted in pig heart coronary arteries. Spatial resolution, fluorescence detection efficiency, pulse broadening effect, and lifetime measurement variability of the FLIm system were systematically evaluated. Current results show that this system is capable of temporarily resolving the fluorescence emission simultaneously in multiple spectral channels in a single pullback sequence. Accurate measurements of fluorescence decay characteristics from arterial segments can be obtained rapidly (e.g., 20 mm in 5 s), and accurate co-registration of fluorescence and ultrasound features can be achieved. The current finding demonstrates the compatibility of FLIm instrumentation with in vivo clinical investigations and its potential to complement conventional IVUS during catheterization procedures. PMID:24898604

  13. Fulminant intravascular lymphomatosis mimicking acute haemorrhagic leukoencephalopathy.

    Science.gov (United States)

    Marino, D; Sicurelli, F; Cerase, A; Tripodi, S; Cintorino, M; Lazzi, S; Federico, A

    2012-09-15

    Intravascular lymphomatosis (IVL) is a rare non-Hodgkin's lymphoma, usually of B cell lineage, characterized by massive angiotropic growth. The clinical presentation of IVL may include changes in mental status, non-localizing neurological deficits, seizures, fever of unknown origin and skin changes. Because of its rarity and the absence of specific diagnostic procedures except for cerebral biopsy, diagnosis is often postmortem. Brain MRI usually shows non-specific abnormalities. The purpose of this case report is to increase the knowledge of clinical and neuroimaging features of IVL by describing the findings observed in a 71-year-old patient. A 71-year-old male was admitted for right hemiparesis, acute cognitive impairment and febricula. A bone marrow biopsy resulted normal. He then developed a rapid progressive impairment of his mental status and left hemisoma motor seizures. Brain CT and MRI were interpreted as consistent with acute haemorrhagic leukoencephalopathy (AHLE), including multiple areas of restricted diffusion without gadolinium enhancement and a small focal area of gadolinium enhancement in the left temporal lobe white matter. The patient died within a few days and the autopsy led to the diagnosis of IVL. IVL may present with a variety of clinical signs and symptoms, including stroke and hemiparesis. IVL may mimic AHLE at brain MRI. However, the evidence of multiple areas of restricted diffusion without gadolinium enhancement and of a small area of gadolinium enhancement could have led to the correct diagnosis. IVL should be added to the differential diagnosis of AHLE at brain MRI. Copyright © 2012 Elsevier B.V. All rights reserved.

  14. Worldwide experience with a totally subcutaneous implantable defibrillator

    DEFF Research Database (Denmark)

    Lambiase, Pier D; Barr, Craig; Theuns, Dominic A M J

    2014-01-01

    AIMS: The totally subcutaneous implantable-defibrillator (S-ICD) is a new alternative to the conventional transvenous ICD system to minimize intravascular lead complications. There are limited data describing the long-term performance of the S-ICD. This paper presents the first large internationa...

  15. Therapeutic intervention in disseminated intravascular coagulation: have we made any progress in the last millennium?

    NARCIS (Netherlands)

    Levi, Marcel; de Jonge, Evert; van der Poll, Tom

    2002-01-01

    Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic intravascular activation of coagulation, leading to widespread deposition of fibrin in the circulation. Recent knowledge on important pathogenetic mechanisms that may lead to DIC has resulted in novel preventive and

  16. Emergency treatment by intravascular embolization in traumatic carotid cavernous fistula

    International Nuclear Information System (INIS)

    Tang Jun; Sun Zengtao; Liu Zuoqin; Liu Yanjun; Li Fengxin

    2006-01-01

    Objective: To discuss the method of intervenfional intravascular treatment in traumatic carotid cavernous fistula (TCCF) and the significance of clinical application in emergency. Methods: In 297 eases of TCCF, 36 cases were treated by interventional intravascular embolization by detachable balloon, embolization orificium or occlusion in one side of carotid artery. In the 36 cases, serious epistaxis occurred in 22 eases, cortical vein inflow in 9 cases, intracranial hemorrhage in 3 cases, aggravation of eyesight in 3 cases, and limb dysfunction in 2 cases. Results: Fistula was successfully embolized and internal carotid artery remained patent in 19 cases. Complete embolization of orificium or internal carotid artery was achieved in 17 eases. The serious epistaxias in 22 cases and intracranial hemorrhage in 3 cases stopped. Eyesight recovered in 2 eases and improved in 1 case. Limb dysfunction improved evidently in 2 cases. Conclusion: Intravascular embolization treatment is the first therapeutic choice for TCCF, especially in emergency. It is necessary, safe and effective. (authors)

  17. Os impactos dos dispositivos móveis nas pessoas

    Directory of Open Access Journals (Sweden)

    Quéven Ribeiro

    2015-10-01

    Full Text Available Percebendo-se que há uso intenso dos dispositivos móveis, como tablets e smartphones, em horários, lugares e situações diversas, principalmente pelos jovens, o presente artigo apresenta considerações comprovadoras de que o uso excessivo desses aparelhos causa danos psicológicos, em maior ou menor grau, aos usuários mais assíduos. Para corroborar essas considerações, realizaram-se pesquisas quantitativas e de campo, com pessoas distintas e de idades variadas. Os resultados demonstram fatos que devem ser examinados com cuidado por pais, responsáveis, educadores, usuários e psicólogos da tecnologia, pois servem de alerta para a situação atual, que certamente terá consequências para os anos seguintes e para as próximas gerações.

  18. UTILIZACIÓN DE OXITETRACICLINA E HIDROCORTISONA PARA EVITAR ADHERENCIAS EN DISPOSITIVOS INTRAVAGINALES EN OVINOS

    Directory of Open Access Journals (Sweden)

    J. L. SOSA

    2017-06-01

    Full Text Available Los dispositivos intravaginales son utilizados para la inducción y sincronización de celos. Los mismos pueden producir adherencia en las paredes de la vagina. El objetivo del presente trabajo fue probar la efi ciencia de la aplicación de antibióticos y corticoide conjuntamente con los dispositivos para evitar adherencias. La experiencia se realizó con 45 ovejas distribuidas en tres grupos: GC dispositivo sin tratamiento, T1 dispositivo más tetraciclina y T2 dispositivo más tetraciclina y corticoide. Siguiendo el protocolo se procedió al retiro de los mismos a los 12 días. Se realizó un test χ2 para evaluar la efectividad del tratamiento. Las ovejas del T2 no presentaron adherencias. En cambio, se observaron distintos grados de adherencias: en el T1 (53 % y en el GC (46 %. Se puede inferir que la utilización de Tetracicilina más hidrocortisona es efi ciente para evitar la vaginitis y por ende la adherencia de los dispositivos y pérdida por disminución de preñeces posteriores al retiro de los dispositivos.

  19. GPLAD: PROGRAMACIÓN ESTRUCTURADA SOBRE DISPOSITIVOS ANDROID

    Directory of Open Access Journals (Sweden)

    LUISA FERNANDA HERNÁNDEZ RAMÍREZ

    2012-12-01

    Full Text Available La programación por medio de bloqueses un enfoque visual que permite a las personas jóvenesadquirir interés en el desarrollo de software.Así lo han demostrado herramientas para computadorescomo Scratch, StarLogo y Alice. Hoy en díahay estudiantes e ingenieros programadores quedesean implementar soluciones más estructuradas yhay pocas herramientas que, a través de programacióngráfica ofrezcan la posibilidad de solucionar problemasque se manejen en primeros semestres universitarios.Por otro lado, los dispositivos móviles, enespecial los que poseen sistema operativo Android,han tenido acogida en los últimos años, además, sonutilizados para resolver problemas en tiempo real.El objetivo de este trabajo fue demostrar la utilidadde una aplicación que soporta la programación estructuradapor medio de bloques sobre dispositivosAndroid, que facilita la creación y ejecución de códigoen el lenguaje Java sobre un servidor remoto. Serealizó un análisis para determinar el ambiente deprogramación, la creación de bloques con su representaciónintermedia y las validaciones para la generaciónde código, además, se realizaron pruebas através de la formulación de problemas matemáticosque se enseñan durante los primeros cursos de Ingenieríade sistemas en la Fundación UniversitariaSan Martín. Finalmente, se obtuvo el código Javade la solución a cada problema planteado dentro deGplad

  20. Editorial: Traducción y dispositivos móviles

    OpenAIRE

    Serón-Ordóñez, Inmaculada

    2016-01-01

    Los dispositivos móviles (tabletas, teléfonos inteligentes,...) están transformando la localización, al haber dado lugar a nuevos sistemas operativos y a una explosión de aplicaciones con sus características propias frente al software de escritorio. En estetrabajo, se presenta el monográfico de Tradumàtica dedicado a las intersecciones entre la traducción y los dispositivos móviles. Dicho monográfico presta especial atención a la traducción de productos concebidos para dispositivos móviles y ...

  1. Coronary artery aneurysm after stent implantation: acute and long-term results after percutaneous treatment with a stent graft.

    Science.gov (United States)

    Rubartelli, Paolo; Terzi, Giacomo; Borgo, Lorenzo; Giachero, Corinna

    2002-03-01

    A patient with unstable angina was treated with elective Palmaz-Schatz stent implantation on a focal stenosis of the left circumflex artery. One year later, a large (13 mm in diameter) coronary artery aneurysm was diagnosed at angiography in the stented site. Intravascular ultrasound examination confirmed the presence of a true aneurysm located at the proximal end of the stent. The aneurysm was successfully treated with a Jostent Graft (Jomed Implantate) consisting of two slotted tube stainless steel stents supporting a polytetrafluoroethylene tube. The stent graft was implanted under intravascular ultrasound guidance. The 18-month angiographic follow-up showed good patency of the stent graft and complete exclusion of the aneurysm.

  2. Covered stent to exclude intravascular thrombus.

    Science.gov (United States)

    Liistro, Francesco; Stankovic, Goran; Di Mario, Carlo; Montorfano, Matteo; Briguori, Carlo; Colombo, Antonio

    2002-04-01

    To describe the utility of stent-graft implantation to avoid distal embolization from a large thrombus-containing lesion. A 67-year-old man was evaluated for recent onset of disabling left leg claudication. Angiography disclosed a mobile lobular mass occluding the left common iliac artery; irregular staining suggested an atherothrombotic lesion. Through a percutaneous ipsilateral access and an 8-F sheath, a balloon-expandable Jostent peripheral stent-graft was positioned with the distal edge immediately proximal to the internal iliac artery ostium. A prominent "waist" at the center of the balloon confirmed entrapment of the thrombotic mass. Completion angiography showed an optimal result with no residual stenosis or evidence of distal embolization. At 6-month follow-up, the patient was asymptomatic with angiographically documented luminal patency and no evidence of in-stent stenosis. Stent-graft implantation appears a viable treatment alternative for thrombus-containing lesions, particularly when the thrombotic material is localized or is in a large vessel.

  3. Intravascular Young's modulus reconstruction using a parametric finite element model

    NARCIS (Netherlands)

    Baldewsing, R.A.; Oomens, C.W.J.; Steen, van der A.F.W.; Yuhas, D.; Schneider, S.C.

    2003-01-01

    IntraVascular UltraSound (IVUS) elastography may be used to detect vulnerable, rupture prone plaques, which are held responsible for the majority of acute coronary syndromes. IVUS elastography accomplishes this by visualising local incremental radial strain of arteries, in so-called elastograms.

  4. 21 CFR 880.5440 - Intravascular administration set.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Intravascular administration set. 880.5440 Section 880.5440 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES GENERAL HOSPITAL AND PERSONAL USE DEVICES General Hospital and Personal Use...

  5. Heartbeat OCT: In vivo intravascular megahertz-optical coherence tomography

    NARCIS (Netherlands)

    T. Wang (Tianshi); A.F.H. Pfeiffer (Andreas); E.S. Regar (Eveline); W. Wieser (Wolfgang); H.M.M. van Beusekom (Heleen); C.T. Lancée (Charles); T. Springeling (Tirza); I. Krabbendam (Ilona); A.F.W. van der Steen (Ton); R. Huber (Roman); G. van Soest (Gijs)

    2015-01-01

    textabstractCardiac motion artifacts, non-uniform rotational distortion and undersampling affect the image quality and the diagnostic impact of intravascular optical coherence tomography (IV-OCT). In this study we demonstrate how these limitations of IV-OCT can be addressed by using an imaging

  6. Mechanical scanning in intravascular ultrasound imaging: Artifacts and driving mechanisms

    NARCIS (Netherlands)

    H. ten Hoff (H.); E.J. Gussenhoven (Elma); C.M. Korbijn (Carin); F. Mastik (Frits); C.T. Lancée (Charles); N. Bom (Klaas)

    1995-01-01

    textabstractObjective: Currently, intravascular ultrasound (US) imaging catheters are developed and produced to provide a complementary diagnostic method in the treatment of blood vessel obstructive disease. Typical catheter dimensions are a diameter of 1–2.5 mm and a length of 1–1.5 m. A real-time

  7. Intravascular catheter related infections in children admitted on the ...

    African Journals Online (AJOL)

    peripheral venous intravascular catheters uncoated with no antibiotic or antiseptic, was done. Social demographic characteristics, anthropometry, clinical examination including the catheter site were determined at enrollment. The children had their blood, catheter tip and hub samples taken off for culture and sensitivity as ...

  8. Disseminated intravascular coagulation in meningococcal sepsis. Case 7

    NARCIS (Netherlands)

    Zeerleder, S.; Zürcher Zenklusen, R.; Hack, C. E.; Wuillemin, W. A.

    2003-01-01

    We report on a man (age: 49 years), who died from severe meningococcal sepsis with disseminated intravascular coagulation (DIC), multiple organ dysfunction syndrome and extended skin necrosis. We discuss in detail the pathophysiology of the activation of coagulation and fibrinolysis during sepsis.

  9. Intravascular catheter sepsis | Mer | South African Medical Journal

    African Journals Online (AJOL)

    Intravascular devices are an integral component of modern-day medical practice. They are used to administer intravenous fluids, medications, blood products and parenteral nutrition. In addition, they serve as a valuable monitor of the haemodynamic status of critically ill patients.

  10. Utilidad de la histeroscopia en el fracaso de extracción de dispositivos intrauterinos

    OpenAIRE

    Zighelboim, Itic

    2004-01-01

    Objetivo: Establecer la utilidad de la histeroscopia para el diagnóstico y extracción de dispositivos intrauterinos con hilos no visibles y fracasos previos de extracción. Método: Se practicaron 106 histeroscopias ambulatorias para localizar y extraer los dispositivos intrauterinos. En todas las pacientes fracasaron intentos previos de extracción por diversos procedimientos. Ambiente: Servicio de Fertilidad, "Maternidad Concepción Palacios", Caracas. Resultados: La extracción de los intrauter...

  11. Desarrollo de un videojuego multiplataforma para dispositivos móviles

    OpenAIRE

    Garzón Hernández, Sandra María

    2015-01-01

    Los dispositivos móviles se han convertido en una de las principales plataformas para videojuegos. Una de las principales problemáticas al desarrollar aplicaciones para estos dispositivos es la alta fragmentación que existe en cuanto a sistemas operativos y características de la interfaz. Existen determinadas librerías y herramientas dirigidas a resolver este problema, permitiendo desarrollar videojuegos que puedan ser portados a las principales plataformas móviles existentes.

  12. Anatomia humana por aplicativos de dispositivos móveis

    Directory of Open Access Journals (Sweden)

    Wiliam Machado Andrade

    2014-07-01

    Full Text Available Em tempos de debates acerca do papel da dissecação cadavérica e sua importância para o ensino de anatomia, quando a prática vem sendo reduzida nos currículos médicos, lojas virtuais de aplicativos para dispositivos móveis passaram a oferecer produtos voltados à apresentação das características do corpo humano. O objetivo do presente texto é discutir a pertinência desses produtos como material de ensino mediado, a partir da análise de um programa voltado à morfologia disponível para tablets e smartphones. Para tanto, a partir de uma abordagem exploratória e descritiva, realizou-se a análise de um exemplo, o aplicativo Visual Anatomy Free, tendo em vista o potencial instrucional do conteúdo e os elementos de interface, observando se nele se apresentam possibilidades de inclusão de tais meios digitais no contexto dos estudos anatômicos.

  13. LOS IMPERATIVOS DE BELLEZA Y EL DISPOSITIVO MÉDICO

    Directory of Open Access Journals (Sweden)

    Ma. Candelaria Ochoa Avalos

    2011-01-01

    Full Text Available En este artículo intentamos releer la tesis central del libro de Naomi Wolf The Beauty Myth: How Images of Beauty Are Used Against Women considerando las narraciones de algunas mujeres que entrevistamos en el marco de una investigación en curso. Naomi Wolf argumenta que las "imágenes de belleza inflexibles y crueles" que definen el "mito de la belleza" constituyen una contraofensiva al feminismo y el movimiento de las mujeres. Como argumentos centrales, Naomi Wolf postula, por un lado, la operación de un poder "represivo" que censura y desvaloriza a las mujeres reales recluyéndolas en el dominio de los intereses privados y, por otro lado, la resistencia o el sometimiento como opciones para enfrentar esta "represión sexual". Por nuestra parte, intentamos complejizar estos planteamientos, recurriendo a las tesis de Michel Foucault sobre la biopolítica, y a los desarrollos de Judith Butler sobre los "mecanismos psíquicos del poder", para concluir que la agencia de las mujeres, en el marco de la decisión de una cirugía cosmética, tiene un carácter paradojal, que implica una sujeción al poder y una habilitación de la agencia en virtud de la "complicidad" fundante con los dispositivos del saber-poder.

  14. Las ciencias sociales y los dispositivos de la complejidad

    Directory of Open Access Journals (Sweden)

    Rodrigo Martínez Díaz

    2013-12-01

    Full Text Available Se presenta una perspectiva de comparación entre los métodos cualitativos y cuantitativos tradicionales de la investigación y las potencialidades del nuevo paradigma del modelamiento y simulación para la investigación en ciencias sociales, sus diferentes métodos y herramientas. Se revisan los criterios de la simulación dinámica, de los autómatas celulares y los agentes y se esbozan las concepciones provenientes de la inteligencia artificial como la vida artificial, las sociedades artificiales y la cultura artificial, que conducen hacia una ciencia social computacional explicativa. El estudio se centra en el Modelamiento y Simulación Basado en Agentes (ABMS, como el dispositivo por excelencia que permite la comprensión y explicación de los fenómenos sociales, su emergencia, evolución y adaptación más que la predicción típica de los demás tipos de simulación. La metodología de los modelos ABMS se posiciona como laboratorio para modificar las condiciones de simulación de los fenómenos reales, y permite construir sociedades artificiales en donde es posible realizar experimentos impedidos por la moral, la ética y/o los costos en la vida real

  15. Newer techniques for intravascular and intraoperative neurointerventional procedures

    International Nuclear Information System (INIS)

    Higashida, R.T.; Halbach, V.V.; Hieshima, G.B.; Yang, P.

    1987-01-01

    A videotape demonstrating newer techniques used in intravascular and intraoperative embolization procedures will be presented. The authors discuss the use of some of the newer embolic agents, real-time digital subtraction angiography, roadmapping techniques, and the use of microcatheters and steerable micro guide wires, which has greatly facilitated neurovascullar embolization procedures and enhanced patient safety. A number of actual intraoperative and intravascular cases will be shown demonstrating treatment of vascular malformations of the brain and spinal cord, carotid cavernous sinus fistulas, aneurysms and dural arteriovenous malformations. The indications for treatment, patient selection, technical preparation and newer methodologies and approaches to complex vascular lesions of the brain and spinal cord are discussed in detail

  16. Intravascular brachytherapy: a model for the calculation of the dose

    International Nuclear Information System (INIS)

    Pirchio, Rosana; Martin, Gabriela; Rivera, Elena; Cricco, Graciela; Cocca, Claudia; Gutierrez, Alicia; Nunez, Mariel; Bergoc, Rosa; Guzman, Luis; Belardi, Diego

    2002-01-01

    In this study we present the radiation dose distribution for a theoretical model with Montecarlo simulation, and based on an experimental model developed for the study of the prevention of restenosis post-angioplasty employing intravascular brachytherapy. In the experimental in vivo model, the atherosclerotic plaques were induced in femoral arteries of male New Zealand rabbits through surgical intervention and later administration of cholesterol enriched diet. For the intravascular irradiation we employed a 32P source contained within the balloon used for the angioplasty. The radiation dose distributions were calculated using the Monte Carlo code MCNP4B according to a segment of a simulated artery. We studied the radiation dose distribution in the axial and radial directions for different thickness of the atherosclerotic plaques. The results will be correlated with the biologic effects observed by means of histological analysis of the irradiated arteries (Au)

  17. Dispositivo para medición de la presión arterial sobre la plataforma Android para dispositivos móviles

    Directory of Open Access Journals (Sweden)

    M. Vinueza

    2013-11-01

    Full Text Available En este proyecto se presenta un dispositivo para la medición de la presión arterial implementado sobre la plataforma Android para su funcionamiento en smartphones y tablets. La implementación consta de software y hardware, la forma de medición del dispositivo se basa en la Técnica Oscilométrica. El software toma en cuenta la interfaz gráfica de usuario, los algoritmos de programación y la lógica de funcionamiento del módulo, todo esto ejecutado en JAVA como lenguaje de Programación. El hardware se compone de una microbomba, una electroválvula y como tarjeta de control y adquisición de datos la IOIO de Android; estos elementos en conjunto permiten la automatización de la medición de la presión arterial. El dispositivo proporciona al paciente una medición de su presión arterial (sistólica, diastólica y media; además, permite tener un registro que se almacena en su dispositivo móvil.

  18. Design of low noise transimpedance amplifier for intravascular ultrasound

    KAUST Repository

    Reda, Dina

    2009-11-01

    In this paper, we study transimpedance amplifiers for capacitive sensing applications with a focus on Intravascular Ultra Sound (IVUS). We employ RF noise cancellation technique on capacitive feedback based transimpedance amplifiers. This technique eliminates the input-referred noise of TIAs completely and enhances the dynamic range of front-end electronics. Simulation results verify the proposed technique used in two different TIA topologies employing shunt-shunt feedback. ©2009 IEEE.

  19. Asian-variant intravascular lymphoma in the African race

    Directory of Open Access Journals (Sweden)

    Holly Geyer

    2012-03-01

    Full Text Available Intravascular large B-cell lymphoma (IVLBCL is an exceptionally rare form of non- Hodgkin lymphoma (NHL distinguished by the preferential growth of neoplastic cells within blood vessel lumen. Challenging to detect and deemed disseminated at diagnosis, this condition is characterized by a highly aggressive, inconspicuous course with a high mortality rate. We describe the case of a 48 year-old African-American female presenting with a two month history of low-grade fevers and malaise. Laboratory data was notable for anemia, thrombocytopenia, elevated liver function tests, and hematuria. An extensive workup for infectious, rheumatologic and malignant causes was negative. Her symptoms progressed and within two weeks, she was admitted for disseminated intravascular coagulation (DIC. Her course was complicated by diffuse pulmonary hemorrhage and ultimately, care was withdrawn. Autopsy identified widespread CD-20 positive intravascular large B-cell lymphoma with significant hepatosplenic involvement, characteristic of the Asian variant IVLBCL. This case uniquely highlights development of the Asian variant IVLBVL in a previously undescribed race. Identified by its intraluminal vascular growth pattern, IVLBCL generally spares lymphatic channels. Diagnosis and differentiation of this condition from other hematological malignancies via skin, visceral and bone marrow biopsy is imperative as anthracycline-containing chemotherapies may significantly improve clinical outcomes. This article outlines the common presentation, natural course, and treatment options of IVLBCL, along with the histopathology, immunohistochemistry, and chromosomal aberrations common to this condition.

  20. Renal denervation by intravascular ultrasound: Preliminary in vivo study

    Science.gov (United States)

    Sinelnikov, Yegor; McClain, Steve; Zou, Yong; Smith, David; Warnking, Reinhard

    2012-10-01

    Ultrasound denervation has recently become a subject of intense research in connection with the treatment of complex medical conditions including neurological conditions, development of pain management, reproduction of skin sensation, neuropathic pain and spasticity. The objective of this study is to investigate the use of intravascular ultrasound to produce nerve damage in renal sympathetic nerves without significant injury to the renal artery. This technique may potentially be used to treat various medical conditions, such as hypertension. The study was approved by the Institutional Animal Care and Use Committee. Ultrasound was applied to renal nerves of the swine model for histopathological evaluation. Therapeutic ultrasound energy was delivered circumferentially by an intravascular catheter maneuvered into the renal arteries. Fluoroscopic imaging was conducted pre-and post-ultrasound treatment. Animals were recovered and euthanized up to 30 hours post procedure, followed by necropsy and tissue sample collection. Histopathological examination showed evidence of extensive damage to renal nerves, characterized by nuclear pyknosis, hyalinization of stroma and multifocal hemorrhages, with little or no damage to renal arteries. This study demonstrates the feasibility of intravascular ultrasound as a minimally invasive renal denervation technique. Further studies are necessary to evaluate the long-term safety and efficacy of this technique and its related clinical significance.

  1. Dispositivo de navegación para personas invidentes basado en la tecnología time of flight

    OpenAIRE

    LENGUA, ISMAEL; DUNAI, LARISA; PERIS FAJARNÉS, GUILLERMO; DEFEZ, BEATRIZ

    2013-01-01

    El artículo presenta un nuevo dispositivo de navegación y detección de obstáculos para las personas ciegas, basado en la tecnología Time-of-Flight y en sonidos acústicos. El dispositivo se ha desarrollado como un dispositivo de ayuda, complementario al bastón, para las personas invidentes. Su objetivo primordial es detectar los obstáculos e informar al usuario mediante sonidos acústicos de la locación de los mismos, tanto en distancia como en dirección. El dispositivo tiene un rango de trabaj...

  2. Design, construction, and validation of a rotary multifunctional intravascular diagnostic catheter combining multispectral fluorescence lifetime imaging and intravascular ultrasound.

    Science.gov (United States)

    Bec, Julien; Xie, Hongtao; Yankelevich, Diego R; Zhou, Feifei; Sun, Yang; Ghata, Narugopal; Aldredge, Ralph; Marcu, Laura

    2012-10-01

    We report the development and validation of an intravascular rotary catheter for bimodal interrogation of arterial pathologies. This is based on a point-spectroscopy scanning time-resolved fluorescence spectroscopy technique enabling reconstruction of fluorescence lifetime images (FLIm) and providing information on arterial intima composition and intravascular ultrasound (IVUS) providing information on arterial wall morphology. The catheter design allows for independent rotation of the ultrasonic and optical channels within an 8 Fr outer diameter catheter sheath and integrates a low volume flushing channel for blood removal in the optical pathways. In the current configuration, the two channels consist of (a) a standard 3 Fr IVUS catheter with single element transducer (40 MHz) and (b) a side-viewing fiber optic (400 μm core). Experiments conducted in tissue phantoms showed the ability of the catheter to operate in an intraluminal setting and to generate coregistered FLIm and IVUS in one pull-back scan. Current results demonstrate the feasibility of the catheter for simultaneous bimodal interrogation of arterial lumen and for generation of robust fluorescence lifetime data under IVUS guidance. These results facilitate further development of a FLIm-IVUS technique for intravascular diagnosis of atherosclerotic cardiovascular diseases including vulnerable plaques.

  3. Ion implantation

    International Nuclear Information System (INIS)

    Dearnaley, Geoffrey

    1975-01-01

    First, ion implantation in semiconductors is discussed: ion penetration, annealing of damage, gettering, ion implanted semiconductor devices, equipement requirements for ion implantation. The importance of channeling for ion implantation is studied. Then, some applications of ion implantation in metals are presented: study of the corrosion of metals and alloys; influence or ion implantation on the surface-friction and wear properties of metals; hyperfine interactions in implanted metals

  4. Intracoronary stent implantation: new approach using a monorail system and new large-lumen 7F catheters from the brachial route.

    Science.gov (United States)

    Jenny, D B; Robert, G P; Fajadet, J C; Cassagneau, B G; Marco, J

    1992-04-01

    In this brief report we describe a case of successful multivessel PTCA with intracoronary stent implantation using a new large-lumen 7F catheter from the left brachial approach. The application of this technique should be considered for intravascular stent implantation when anticoagulation ideally should not be interrupted or in anatomical situations limiting femoral vascular access.

  5. Prototipo de dispositivo de medida de rendimiento en deportes de contacto basado en un acelerómetro triaxial y comunicación a dispositivo móvil

    OpenAIRE

    ARÁNDIGA MARTÍNEZ, ADRIÁN LUIS

    2016-01-01

    Arándiga Martínez, AL. (2016). Prototipo de dispositivo de medida de rendimiento en deportes de contacto basado en un acelerómetro triaxial y comunicación a dispositivo móvil. http://hdl.handle.net/10251/75671. TFGM

  6. El dispositivo pedagógico: una visión desde la música

    Directory of Open Access Journals (Sweden)

    Ligia Ivette Asprilla

    2007-01-01

    Full Text Available Consideramos que la prueba de musicalidad es un poderoso dispositivo pedagógico por su carácter estratégico y su capacidad para desencadenar procesos de formación musical; si la pensamos como abanico de posibilidades cognitivo-creativas y artificio pedagógico es un dispositivo de creación; en su condición generadora de vivencias auditivas, nodos investigativos, expresión de una intencionalidad política y microcosmos cultural, la prueba de musicalidad es un dispositivo creador; es también auto-re-creador, en cuanto no sólo transforma, sino que lleva en sí misma el germen de su re-constitución.

  7. El dispositivo pedagógico: una visión desde la música

    Directory of Open Access Journals (Sweden)

    Gisela de la Guardia

    2007-10-01

    Full Text Available Consideramos que la prueba de musicalidad es un poderoso dispositivo pedagógico por su carácter estratégico y su capacidad para desencadenar procesos de formación musical; si la pensamos como abanico de posibilidades cognitivo-creativas y artificio pedagógico es un dispositivo de creación; en su condición generadora de vivencias auditivas, nodos investigativos, expresión de una intencionalidad política y microcosmos cultural, la prueba de musicalidad es un dispositivo creador; es también auto-re-creador, en cuanto no sólo transforma, sino que lleva en sí misma el germen de su re-constitución.

  8. Dispositivos estéticos y formas sensibles de la emancipación

    Directory of Open Access Journals (Sweden)

    María Luciana Cadahia

    2016-08-01

    Full Text Available Se explora la noción de dispositivo desde una perspectiva estético-política. Se inquieren los motivos para distanciarnos de las lecturas de Agamben, Esposito y el Colectivo tiqqun,se examina la interpretación de Deleuze al respecto, en una dimensión poco conocida, y se amplía esta perspectiva hacia una concepción estética del dispositivo, atendiendo para ello a Martín-Barbero. Finalmente, se considera el vínculo problemático entre el dispositivo y la positividad estética, para acercarnos a Schiller, quien da las pautas para disolver el vínculo problemático.

  9. Controle de dispositivos em estufa agrícola / Agricultural greenhouse control of devices

    Directory of Open Access Journals (Sweden)

    Ricardo A. Bona

    2008-05-01

    Full Text Available Este artigo mostra a possibilidade de se coletar dados e controlar dispositivos e sensores através das portas serial e paralela de um computador, com aplicabilidade em uma estufa agrícola. Os dados coletados são: temperatura, umidade, pressão, estado da porta de acesso e das janelas. Os dispositivos controlados são: janela motorizada, exaustor, torneira e lâmpada. Um software está sendo desenvolvido para analisar, em tempo real, os dados coletados de sensores e realizar o controle dos dispositivos, tomando decisões como, por exemplo, abertura ou fechamento da janela da estufa. O software analisa, também, variáveis coletadas dos sensores e mostra resultados obtidos de forma gráfi ca

  10. Impact of peri-stent remodeling on restenosis: a volumetric intravascular ultrasound study.

    Science.gov (United States)

    Nakamura, M; Yock, P G; Bonneau, H N; Kitamura, K; Aizawa, T; Tamai, H; Fitzgerald, P J; Honda, Y

    2001-05-01

    Vessel remodeling is an important mechanism of late lumen loss after nonstent coronary interventions. However, its impact on in-stent restenosis has not been systematically investigated. Serial volumetric intravascular ultrasound analyses (poststent and follow-up) were performed in 55 lesions treated with a balloon-expandable stent (ACS MultiLink) using standard stent deployment techniques. The vessel volume (VV), lumen volume (LV), and volume bordered by the stent (SV) were measured using Simpson's method. The volume of plaque and neointima outside the stent (peri-stent volume, PSV) and volume of neointima within the stent (intrastent volume) were also measured. The change of each parameter during the follow-up period (follow-up minus poststent) was calculated and then divided by SV to normalize these values (designated as percent change [%]). As expected, %PSV directly correlated with %VV (Pexterior to a coronary stent occurs to a variable degree after stent implantation. There is a distinct trade-off between positive remodeling and in-stent hyperplasia: in segments in which the degree of peri-stent remodeling is less, intrastent neointimal proliferation is greater and accompanied by more significant late lumen loss.

  11. Realidad aumentada en dispositivos iOS como sistema de ayuda a los alumnos

    OpenAIRE

    Villaran Molina, Diego

    2012-01-01

    Este Proyecto consiste en la realización de! una aplicación destinada a los alumnos de la Universidad para obtener ayuda e información del Campus Universitario. La aplicación se ejecuta en dispositivos móviles iOS: iPhone, iPad e iPod Touch y emplea tecnologías de Realidad Aumentada proporcionadas por el SDK Vuforia de Qualcomm. Esta aplicación servirá como nexo de unión entre soportes, a priori incompatibles, como una simple hoja de papel impresa y el propio dispositivo electrónico haciendo ...

  12. Actividades de aprendizaje utilizando sensores de dispositivos móviles personales

    OpenAIRE

    González Gancedo, Santiago

    2015-01-01

    Este trabajo se centra en el diseño de actividades innovadoras centradas en dispositivos móviles, de manera que los estudiantes puedan realizarlas con su propio teléfono móvil (BYOD-Bring Your Own Device). La utilización de estos dispositivos aporta productividad personal, reducción de barreras entre el aprendizaje formal e informal, fomento del aprendizaje social y del “aprender haciendo”, reduciendo costes considerablemente. Las principales aportaciones de este trabajo consis...

  13. Uso de dispositivos móviles y BYOD: Su impacto en la seguridad

    OpenAIRE

    Macia, Nicolás; Lanfranco, Einar Felipe; Venosa, Paula; Sabolansky, Alejandro Javier

    2015-01-01

    Los dispositivos móviles son un elemento cada vez mas arraigado en la vida diaria de las personas. Debido a la introducción de estas tecnologías tanto en la vida privada de las personas como en el ámbito laboral de estas, la seguridad de dichos dispositivos se ha convertido en una preocupación creciente en la sociedad. Entre los alcances esperados de esta línea de I/D/I se encuentra el análisis de distintos problemas de seguridad a los que una persona se expone cuando utiliza estos disposi...

  14. Verificación del hablante mediante dispositivos móviles en entornos ruidosos

    OpenAIRE

    Etchart, Graciela; Ruíz, Silvia; Miranda, Ernesto; Aguirre, Juan José; Herlein, Mauro; Alvez, Carlos E.

    2017-01-01

    El interés por las aplicaciones biométricas ha crecido considerablemente en los últimos años debido a que han surgido nuevos servicios que necesitan formas confiables para autenticar a sus usuarios. En este trabajo se abordará la biometría de voz, a través de dispositivos móviles, para la verificación de la identidad del hablante. Actualmente, los dispositivos móviles proporcionan una plataforma conveniente para la captura de voz y su transferencia para la verificación remota. Sin embar...

  15. Integración de dispositivos IoT en una red comunitaria

    OpenAIRE

    Reyes Díez, Alejandro

    2017-01-01

    Conforme se va expandiendo el Internet de las Cosas (IoT) la demanda de dispositivos interconectados aumenta. Como respuesta, se han comenzado a desarrollar estándares que ofrecen alto rango de cobertura y bajo consumo energético, características que serán indispensables en un nuevo escenario en el que se prevé que multitud de dispositivos precisen de gran conectividad. Uno de los estándares que más despunta es LPWAN, que optimiza el alcance, la vida de la batería y el coste...

  16. Sistema de monitorización de equipos remotos mediante dispositivos Android

    OpenAIRE

    Cruz Sánchez, Mario

    2015-01-01

    Este proyecto describe el desarrollo práctico de un sistema de telecontrol y tele medida basado en dispositivos Android. Dispondremos de varios equipos autónomos equipados con un módem GPRS, un receptor GPS y dos entradas analógicas para medir dos magnitudes variables. Estos equipos enviarán datos a un servidor que los almacenará en una base de datos. A través de dispositivos Android se podrán hacer lecturas de las mediciones de cada sensor en tiempo real y mostrar informes de ...

  17. Uso de un dispositivo intravaginal para el control del estro en yeguas

    OpenAIRE

    Wilde, Oscar R; de la Vega, Adolfo C; L. Cruz, María

    2002-01-01

    Un dispositivo intravaginal de uso bovino (PRID) conteniendo progesterona de lenta liberación, fue evaluado en once yeguas de la raza Peruano de Paso con el fin de sincronizar sus celos. El dispositivo fue instalado tal como es presentado comercialmente para bovinos y se mantuvo in situ por un lapso de doce días, al cabo de los cuales fue retirado sin mayores complicaciones. Manifestaciones de celo fueron observadas a las 24 h después del retiro del PRID, con su más alta incidencia (50%) a la...

  18. Capítulo 12. Dispositivos de asistencia ventricular: una realidad en Colombia

    OpenAIRE

    Echeverría, Luis E.; Salazar, Leonardo; Torres, Ángela; Figueredo, Antonio

    2016-01-01

    Introducción: La insuficiencia cardiaca es una de las causas prevalentes de morbimortalidad en el mundo. A pesar de la mejoría en la terapia médica y los dispositivos de estimulación cardiaca, existe un porcentaje de pacientes que progresan a falla cardiaca refractaria y sus opciones se reducen a inotrópicos, trasplante cardiaco y dispositivos de asistencia ventricular. Objetivo: Presentar las alternativas actuales de asistencia ventricular disponibles para los pacientes con falla cardiaca...

  19. Dispositivos de microfluídica basados en papel: orígenes, presente y perspectivas

    OpenAIRE

    Berli, Claudio L.A.

    2017-01-01

    Los dispositivos de microfluídica denominados laboratorios en chips se han consolidado como la nueva tecnología para ensayos de laboratorio y sus aplicaciones continúan expandiéndose. En este ámbito de permanente innovación, el papel ha emergido recientemente como un sustrato de gran interés, particularmente para fabricar dispositivos portables, autónomos y de bajo costo, con aplicaciones en diagnóstico médico, cuidado personal, control de calidad de alimentos y monitoreo ambiental. Los micro...

  20. Why Have So Many Intravascular Glucose Monitoring Devices Failed?

    Science.gov (United States)

    Smith, John L; Rice, Mark J

    2015-07-01

    Secondary to the inherent limitations of both point-of-care and central laboratory glucose technologies, continuous glucose measurement has recently enjoyed a high level of investment. Because of the perceived advantages by some of measuring in the intravascular space compared to the subcutaneous tissue, a number of technologies have been developed. In this review, we evaluate nine systems that have shown promise, although only one of these has been cleared for sale in the United States. The detection methodology, regulatory status, technical issues, and company circumstance surrounding each technology are examined. © 2015 Diabetes Technology Society.

  1. Prevention of adverse reactions to intravascular contrast media

    International Nuclear Information System (INIS)

    Soyer, P.; Levesque, M.

    1990-01-01

    The exact mechanisms of adverse reactions to contrast media are still imperfectly known. However, these reactions may be classified as idiosyncratic. Non-idiosyncratic reactions can be prevented by using new, non-ionic contrast agents. Idiosyncratic reactions can be prevented by specific premedication. Patients with a history of idiosyncratic reaction may benefit from corticosteroids and antihistamines administered prophylactically. Patients who seem to be more likely than others to react to contrast media must be premedicated, the risk of reaction being identified and evaluated by questioning. It has recently been suggested that all patients about to receive an intravascular injection of contrast medium should also be premedicated [fr

  2. Protection against high intravascular pressure in giraffe legs

    DEFF Research Database (Denmark)

    Petersen, Karin K; Hørlyck, Arne; Østergaard, Kristine Hovkjær

    2013-01-01

    The high blood pressure in giraffe leg arteries renders giraffes vulnerable to edema. We investigated in 11 giraffes whether large and small arteries in the legs and the tight fascia protect leg capillaries. Ultrasound imaging of foreleg arteries in anesthetized giraffes and ex vivo examination....... All three findings can contribute to protection of the capillaries in giraffe legs from a high arterial pressure....... revealed abrupt thickening of the arterial wall and a reduction of its internal diameter just below the elbow. At and distal to this narrowing, the artery constricted spontaneously and in response to norepinephrine and intravascular pressure recordings revealed a dynamic, viscous pressure drop along...

  3. Dose-volume histograms based on serial intravascular ultrasound: a calculation model for radioactive stents

    International Nuclear Information System (INIS)

    Kirisits, Christian; Wexberg, Paul; Gottsauner-Wolf, Michael; Pokrajac, Boris; Ortmann, Elisabeth; Aiginger, Hannes; Glogar, Dietmar; Poetter, Richard

    2001-01-01

    Background and purpose: Radioactive stents are under investigation for reduction of coronary restenosis. However, the actual dose delivered to specific parts of the coronary artery wall based on the individual vessel anatomy has not been determined so far. Dose-volume histograms (DVHs) permit an estimation of the actual dose absorbed by the target volume. We present a method to calculate DVHs based on intravascular ultrasound (IVUS) measurements to determine the dose distribution within the vessel wall. Materials and methods: Ten patients were studied by intravascular ultrasound after radioactive stenting (BX Stent, P-32, 15-mm length) to obtain tomographic cross-sections of the treated segments. We developed a computer algorithm using the actual dose distribution of the stent to calculate differential and cumulative DVHs. The minimal target dose, the mean target dose, the minimal doses delivered to 10 and 90% of the adventitia (DV10, DV90), and the percentage of volume receiving a reference dose at 0.5 mm from the stent surface cumulated over 28 days were derived from the DVH plots. Results were expressed as mean±SD. Results: The mean activity of the stents was 438±140 kBq at implantation. The mean reference dose was 111±35 Gy, whereas the calculated mean target dose within the adventitia along the stent was 68±20 Gy. On average, DV90 and DV10 were 33±9 Gy and 117±41 Gy, respectively. Expanding the target volume to include 2.5-mm-long segments at the proximal and distal ends of the stent, the calculated mean target dose decreased to 55±17 Gy, and DV 90 and DV 10 were 6.4±2.4 Gy and 107±36 Gy, respectively. Conclusions: The assessment of DVHs seems in principle to be a valuable tool for both prospective and retrospective analysis of dose-distribution of radioactive stents. It may provide the basis to adapt treatment planning in coronary brachytherapy to the common standards of radiotherapy

  4. Thyroid storm complicated by bicytopenia and disseminated intravascular coagulation.

    Science.gov (United States)

    Tokushima, Yoshinori; Sakanishi, Yuta; Nagae, Kou; Tokushima, Midori; Tago, Masaki; Tomonaga, Motosuke; Yoshioka, Tsuneaki; Hyakutake, Masaki; Sugioka, Takashi; Yamashita, Shu-ichi

    2014-07-24

    Male, 23. Thyroid storm. Delirium • diarrhea • fever • hypertension • hyperventilation • tachycardia • weight loss. -. -. Endocrinology and Metabolic. Unusual clinical course. The clinical presentation of thyroid storm includes fever, tachycardia, hypertension, and neurological abnormalities. It is a serious condition with a high mortality rate. Furthermore, some other complications affect the clinical course of thyroid storm. Although it is reported that prognosis is poor when thyroid storm is complicated by disseminated intravascular coagulation syndrome (DIC) and leukopenia, reports of such cases are rare. A 23-year-old man presented with delirium, high pyrexia, diarrhea, and weight loss of 18 kg over 2 months. According to the criteria of Burch and Wartofsky, he was diagnosed with thyroid storm on the basis of his symptom-complex and laboratory data that confirmed the presence of hyperthyroidism. Investigations also found leukopenia, thrombocytopenia, and disseminated intravascular coagulation, all of which are very rare complications of thyroid storm. We successfully treated him with combined therapy including anti-thyroid medication, despite leukopenia. Early diagnosis and treatment are essential in ensuring a good outcome for patients with this rare combination of medical problems.

  5. Intravascular photoacoustic imaging: a new tool for vulnerable plaque identification.

    Science.gov (United States)

    Jansen, Krista; van Soest, Gijs; van der Steen, Antonius F W

    2014-06-01

    The vulnerable atherosclerotic plaque is believed to be at the root of the majority of acute coronary events. Even though the exact origins of plaque vulnerability remain elusive, the thin-cap fibroatheroma, characterized by a lipid-rich necrotic core covered by a thin fibrous cap, is considered to be the most prominent type of vulnerable plaque. No clinically available imaging technique can characterize atherosclerotic lesions to the extent needed to determine plaque vulnerability prognostically. Intravascular photoacoustic imaging (IVPA) has the potential to take a significant step in that direction by imaging both plaque structure and composition. IVPA is a natural extension of intravascular ultrasound that adds tissue type specificity to the images. IVPA utilizes the optical contrast provided by the differences in the absorption spectra of plaque components to image composition. Its capability to image lipids in human coronary atherosclerosis has been shown extensively ex vivo and has recently been translated to an in vivo animal model. Other disease markers that have been successfully targeted are calcium and inflammatory markers, such as macrophages and matrix metalloproteinase; the latter two through application of exogenous contrast agents. By simultaneously displaying plaque morphology and composition, IVPA can provide a powerful prognostic marker for disease progression, and as such has the potential to transform the current practice in percutaneous coronary intervention. Copyright © 2014 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  6. High speed intravascular photoacoustic imaging of atherosclerotic arteries (Conference Presentation)

    Science.gov (United States)

    Piao, Zhonglie; Ma, Teng; Qu, Yueqiao; Li, Jiawen; Yu, Mingyue; He, Youmin; Shung, K. Kirk; Zhou, Qifa; Kim, Chang-Seok; Chen, Zhongping

    2016-02-01

    Cardiovascular disease is the leading cause of death in the industrialized nations. Accurate quantification of both the morphology and composition of lipid-rich vulnerable atherosclerotic plaque are essential for early detection and optimal treatment in clinics. In previous works, intravascular photoacoustic (IVPA) imaging for detection of lipid-rich plaque within coronary artery walls has been demonstrated in ex vivo, but the imaging speed is still limited. In order to increase the imaging speed, a high repetition rate laser is needed. In this work, we present a high speed integrated IVPA/US imaging system with a 500 Hz optical parametric oscillator laser at 1725 nm. A miniature catheter with 1.0 mm outer diameter was designed with a 200 μm multimode fiber and an ultrasound transducer with 45 MHz center frequency. The fiber was polished at 38 degree and enclosed in a glass capillary for total internal reflection. An optical/electrical rotary junction and pull-back mechanism was applied for rotating and linearly scanning the catheter to obtain three-dimensional imaging. Atherosclerotic rabbit abdominal aorta was imaged as two frame/second at 1725 nm. Furthermore, by wide tuning range of the laser wavelength from 1680 nm to 1770 nm, spectroscopic photoacoustic analysis of lipid-mimicking phantom and an human atherosclerotic artery was performed ex vivo. The results demonstrated that the developed IVPA/US imaging system is capable for high speed intravascular imaging for plaque detection.

  7. Intravascular stenting (IVaS) method for fingertip replantation.

    Science.gov (United States)

    Narushima, Mitsunaga; Mihara, Makoto; Koshima, Isao; Gonda, Koichi; Takuya, Iida; Kato, Harunosuke; Nakanishi, Kenji; Yamamoto, Yusuke; Araki, Jun; Abe, Hiroaki; Mundinger, Gerhard S; Kikuchi, Kazuki; Uehara, Eri

    2009-01-01

    Remarkable progress has been made in microsurgery. However, fingertip replantation following amputation has not gained much popularity because of its technical difficulty. We have developed the intravascular stenting (IVaS) method, in which a nylon monofilament is placed inside the vessel lumen to act as a temporary stent, facilitating anastomosis completion. This report describes 7 fingertip replantations using the IVaS method. Intravascular stent size varied from 4-0 to 6-0 (0.199-0.07 mm diameter). There were no cases in which the back wall of a vessel became inadvertently caught in the anastomosis. The overall survival rate for distal digital replants was 85% (6/7 replants). It is very difficult to evenly anastomose vessels of differing diameter, especially on a supermicrosurgical scale. In this respect, the IVaS method plays a role in stably anchoring the 2 vessel ends, allowing for the even spacing of suture knots, even in vessels of different caliber. Because of its ease of use and exactitude, many surgeons may be able to use the IVaS method to reliably complete small anastomoses in fingertip replantations.

  8. Late adverse reactions to intravascular iodinated contrast media

    International Nuclear Information System (INIS)

    Webb, Judith A.W.; Stacul, Fulvio; Thomsen, Henrik S.; Morcos, Sameh K.

    2003-01-01

    Late adverse reactions to intravascular iodinated contrast media are defined as reactions occurring 1 h to 1 week after contrast medium injection. They have received increasing interest over the past decade, but their prevalence remains uncertain and their pathophysiology is not fully understood. The Contrast Media Safety Committee of the European Society of Urogenital Radiology decided to review the literature and to issue guidelines. An extensive literature search was carried out and summarized in a report. Based on the available information, simple guidelines have been drawn up. The report and guidelines were discussed at the 8th European Symposium on Urogenital Radiology in Genoa. Late adverse reactions after intravascular iodinated contrast medium include symptoms such as nausea, vomiting, headache, itching, skin rash, musculoskeletal pain, and fever. A significant proportion of these reactions is unrelated to the contrast medium; however, allergy-like skin reactions are well-documented side effects of contrast media with an incidence of approximately 2%. Late reactions appear to be commoner after non-ionic dimers. The majority of late skin reactions after contrast medium exposure are probably T-cell-mediated allergic reactions. Patients at increased risk of late skin reactions are those with a history of previous contrast medium reaction and those on interleukin-2 treatment. Most skin reactions are self-limiting and resolve within a week. Management is symptomatic and similar to the management of other drug-induced skin reactions. (orig.)

  9. Desarrollo de aplicación para dispositivo móvil : GESMED

    OpenAIRE

    de Gregorio Melgar, Jesús

    2013-01-01

    Desarrollo de aplicación para dispositivo móvil en plataforma Android de gestión básica de servicios médicos. Desenvolupament d'aplicació per a dispositiu mòbil en plataforma Android de gestió bàsica de serveis mèdics.

  10. O grupo como dispositivo das relações sociais do sujeito

    NARCIS (Netherlands)

    R. Quadros Rigoni (Rafaela); T.G. Santi (Thais); G.S. Campos (Gracielie)

    2007-01-01

    textabstractRESUMO: Pensar o grupo como um dispositivo de transformação nas relações dos sujeitos parece uma tarefa intensa; neste trabalho nos propomos a pensar questões grupais e as transformações subjetivas que ocorreram no desenrolar desse território que foi criado, dando ênfase ao processo de

  11. Intravascular Ultrasound Imaging of Peripheral Arteries as an Adjunct to Balloon Angioplasty and Atherectomy

    International Nuclear Information System (INIS)

    Korogi, Yukunori; Hirai, Toshinori; Takahashi, Mutsumasa

    1996-01-01

    This article reviews many of the applications of intravascular ultrasound (US) imaging for peripheral arterial diseases. In vitro studies demonstrate an excellent correlation between ultrasound measurements of lumen and plaque crossectional area compared with histologic sections. In vivo clinical studies reveal the enhanced diagnostic capabilities of this technology compared with angiography. Intravascular US imaging can provide valuable information on the degree, eccentricity, and histologic type of stenosis before intervention, and on the morphological changes in the arterial wall and the extent of excision after intervention. Intravascular US may also serve as a superior index for gauging the diameter of balloon, stent, laser probe, and/or atherectomy catheter appropriate for a proposed intervention. Significant new insights into the mechanisms of balloon angioplasty and atherectomy have been established by intravascular US findings. Intravascular US imaging has been shown to be a more accurate method than angiography for determining the cross-sectional area of the arterial lumen, and for assessing severity of stenosis. Quantitative assessment of the luminal cross-sectional area after the balloon dilatation should be more accurate than angiography as intimal tears or dissections produced by the dilatation may not be accurately evaluated with angiography. At the present time, intravascular US is still a controversial imaging technique. Outcome studies are currently being organized to assess the clinical value and cost effectiveness of intravascular ultrasound in the context of these interventional procedures

  12. BMMobile: uma linha de produtos para dimensionamento de bombeio mecânico em dispositivos móveis

    OpenAIRE

    Sousa, Matheus Alves de

    2010-01-01

    Com o aumento da capacidade de processamento, armazenamento e a variedade de tipos de comunicação existentes, como Bluetooth, infravermelho, redes sem fio, etc., os dispositivos móveis deixaram de ser apenas dispositivos com função especifica e passaram a ser ferramentas com diversos tipos de funcionalidade. No campo empresarial os benefícios que estes tipos de dispositivos oferecem são consideráveis, uma vez que a portabilidade permite que tarefas que antes só poderiam ser ...

  13. Design and implementation of an intravascular brachytherapy installation in cardiology

    International Nuclear Information System (INIS)

    Prieto, C.; Vano, E.; Fernandez, J.M.; Sabate, M.; Galvan, Y.C.

    2001-01-01

    Intravascular Brachytherapy (IVB) is a very promising technique for reducing restenosis rates. However, neither the exact absolute dose needed nor the optimal spatial and temporal distribution of dose inside the vessel wall for a successful treatment, nor the physical dosimetry of the various radioactive sources and devices for dose delivery, are well known. In this paper, an overview will be given of the design strategy, the dosimetric and radiation protection-related problems that we have met during the implementation of this technique at San Carlos hospital, adopted or foreseen solutions, and future research fields that we intend to carry out in order to reduce uncertainties and to achieve a deeper knowledge of the parameters that have an influence on the treatment. (author)

  14. Robust intravascular optical coherence elastography by line correlations

    International Nuclear Information System (INIS)

    Soest, Gijs van; Mastik, Frits; Jong, Nico de; Steen, Anton F W van der

    2007-01-01

    We present a new method for intravascular optical coherence elastography, which is robust against motion artefacts. It employs the correlation between adjacent lines, instead of subsequent frames. Pressure to deform the tissue is applied synchronously with the line scan rate of the optical coherence tomography (OCT) instrument. The viability of the method is demonstrated with a simulation study. We find that the root mean square (rms) error of the displacement estimate is 0.55 μm, and the rms error of the strain is 0.6%. It is shown that high-strain spots in the vessel wall, such as observed at the sites of vulnerable atherosclerotic lesions, can be detected with the technique

  15. Emerging Technology Update Intravascular Photoacoustic Imaging of Vulnerable Atherosclerotic Plaque.

    Science.gov (United States)

    Wu, Min; Fw van der Steen, Antonius; Regar, Evelyn; van Soest, Gijs

    2016-10-01

    The identification of vulnerable atherosclerotic plaques in the coronary arteries is emerging as an important tool for guiding atherosclerosis diagnosis and interventions. Assessment of plaque vulnerability requires knowledge of both the structure and composition of the plaque. Intravascular photoacoustic (IVPA) imaging is able to show the morphology and composition of atherosclerotic plaque. With imminent improvements in IVPA imaging, it is becoming possible to assess human coronary artery disease in vivo . Although some challenges remain, IVPA imaging is on its way to being a powerful tool for visualising coronary atherosclerotic features that have been specifically associated with plaque vulnerability and clinical syndromes, and thus such imaging might become valuable for clinical risk assessment in the catheterisation laboratory.

  16. Theoretical model of intravascular paramagnetic tracers effect on tissue relaxation

    DEFF Research Database (Denmark)

    Kjølby, Birgitte Fuglsang; Østergaard, Leif; Kiselev, Valerij G

    2006-01-01

    The concentration of MRI tracers cannot be measured directly by MRI and is commonly evaluated indirectly using their relaxation effect. This study develops a comprehensive theoretical model to describe the transverse relaxation in perfused tissue caused by intravascular tracers. The model takes...... into account a number of individual compartments. The signal dephasing is simulated in a semianalytical way by embedding Monte Carlo simulations in the framework of analytical theory. This approach yields a tool for fast, realistic simulation of the change in the transverse relaxation. The results indicate...... with bulk blood. The enhancement of relaxation in tissue is due to the contrast in magnetic susceptibility between blood vessels and parenchyma induced by the presence of paramagnetic tracer. Beyond the perfusion measurements, the results can be applied to quantitation of functional MRI and to vessel size...

  17. Evaluation of Disseminated Intravascular Coagulation in the Craniocerebral Traumas

    Directory of Open Access Journals (Sweden)

    Faruk Altinel

    2014-06-01

    Full Text Available Traumatic injury is one of the most important cause of disseminated intravascular coagulation (DIC. It occurs because of blood loss and hemodilution due to fluid resuscitation. The incidence of trauma associated DIC is mainly higher in the craniocerebral traumas. Even though craniocerebral trauma related DIC is well defined, the pathophysiology has been poorly characterized in the literature. Due to the fact that brain tissue is highly significant for procoagulant molecules, craniocerebral traumas are closely related to DIC. In the current study, 30 patients admitted to emergency room have been considered on the first and fifth day of admission to the hospital for the coagulation tests to evaluate DIC in both two groups. [Cukurova Med J 2014; 39(3.000: 488-495

  18. In vivo evaluation of axial integrity of coronary stents using intravascular ultrasound: Insights on longitudinal stent deformation.

    Science.gov (United States)

    Dvir, Danny; Kitabata, Hironori; Barbash, Israel M; Minha, Sa'ar; Badr, Salem; Loh, Joshua P; Chen, Fang; Torguson, Rebecca; Waksman, Ron

    2014-09-01

    To evaluate the axial integrity of different coronary stents using intravascular ultrasound (IVUS). Longitudinal stent deformation was recently reported. Consecutive patients who underwent IVUS analysis after drug-eluting stent (DES) implantation for de novo coronary lesions were evaluated. Stent length was compared with label length for calculation of absolute change and relative difference (absolute change divided by label length). A total of 233 DES utilizing five different platforms were included. The median absolute change in stent length was 0.90 mm (interquartile range [IQR] 0.48-1.39) and the relative difference was 5.24% (IQR 2.55-8.29). There was no significant difference among the groups in median absolute or relative change: Cypher 0.89 mm/3.89%, Taxus 0.88 mm/5.39%, Endeavor 1.16 mm/6.77%, Xience V 0.86 mm/5.80%, and PROMUS Element 0.79 mm/5.34% (P = 0.085, P = 0.072, respectively). Multivariate logistic regression revealed that the Cypher stent was independently correlated with a lower change in length, whereas stent label length and deployment pressure were correlated with higher absolute change. The axial integrity of DES platforms examined in vivo was high, with only mild changes in stent length after implantation. While there are differences between first- and second-generation DES, axial integrity among second-generation DES was similar. © 2013 Wiley Periodicals, Inc.

  19. Intravascular ultrasound-guided optimized stent deployment. Immediate and 6 months clinical and angiographic results from the Multicenter Ultrasound Stenting in Coronaries Study (MUSIC Study)

    Science.gov (United States)

    de Jaegere, P; Mudra, H; Figulla, H; Almagor, Y; Doucet, S; Penn, I; Colombo, A; Hamm, C; Bartorelli, A; Rothman, M; Nobuyoshi, M; Yamaguchi, T; Voudris, V; DiMario, C; Makovski, S; Hausmann, D; Rowe, S; Rabinovich, S; Sunamura, M; van Es, G A

    1998-08-01

    A study was set up to validate the safety and feasibility of intravascular ultrasound-guided stenting without subsequent anticoagulation, and its impact on the 6 months restenosis rate. The study was designed to be multicentred, prospective, and observational. One hundred and sixty-one patients with stable angina and a de novo coronary artery lesion were enrolled. In four patients, the implantation of a Palmaz-Schatz (with spiral bridge) stent had failed. One of these four patients died 3 days following bypass surgery. In two other patients, intravascular ultrasound assessment was not performed. One hundred and twenty-five of the remaining 155 patients (81%) were treated with aspirin (100 mg x day(-1)), because all three criteria for optimized stent expansion were met. Twenty-two of the remaining 38 patients (25%), in whom at least one criterion was not met were treated with aspirin and acenocoumarol (3 months, INR 2.5-3.5), while 16 patients only received aspirin. Stent thrombosis was documented in two patients (1.3%) for which repeat angioplasty was performed. During the hospital stay, there were no deaths or Q-wave myocardial infarctions. Five patients (3.2%) sustained a non-Q-wave myocardial infarction. During the follow-up period (198+/-38 days, complete for all patients, except one), one patient (0.6%) sustained a Q-wave myocardial infarction, one (0.6%) underwent bypass surgery, and repeat angioplasty was performed in nine patients (5.7%). In two of the nine patients, repeat angioplasty involved another lesion. Therefore, the target lesion revascularization rate during follow-up was 4.5% (seven patients). At quantitative coronary angiography, the minimal lumen diameter (mean+/-SD) increased from 1.12+/-0.34 mm before to 2.89+/-0.35 mm after stenting. Repeat angiography at 6 months was performed in 144 patients (92%). The minimal lumen diameter at follow-up was 2.12+/-0.67 mm. Restenosis (diameter stenosis of 50% or more) was documented in 12 patients or 8

  20. Prototipo de dispositivo de medida de rendimiento en running basado en acelerómetro triaxial y comunicación a dispositivo móvil

    OpenAIRE

    MELIÀ DE LA ASUNCIÓN, SERGI

    2016-01-01

    [ES] Debido al creciente número de practicantes del deporte conocido de forma vulgar como ‘running’, se ha abierto un gran mercado para las aplicaciones y dispositivos relacionados con la monitorización de esta actividad. La aplicación desarrollada mediante Android, establecerá comunicación con los sensores alojados en el ‘CC2541 SensorTag’ para estudiar su viabilidad como posible puente para la fabricación de posteriores sistemas de medida de rendimiento. Melià De La Asunci...

  1. Application of chronic intravascular blood glucose sensor in dogs.

    Science.gov (United States)

    Armour, J C; Lucisano, J Y; McKean, B D; Gough, D A

    1990-12-01

    An intravenous glucose sensor was implanted in six dogs for 1-15 wk. The glucose sensor is a flexible cylinder, approximately 0.2 cm diam and 30 cm long, with a tip containing immobilized glucose oxidase and catalase coupled to a potentiostatic O2 sensor. The sensor and a similar O2 reference sensor were implanted in the superior vena cava near the entrance of the right atrium. The sensor response was conveyed externally either by a telemetry system implanted nearby, surgically accessed leads, or chronically maintained percutaneous leads. Summing over the six implants, there was a total implantation period of 333 days during which glucose sensors were functional on demand. The sensor response showed agreement with conventionally assayed blood samples after accounting for a response lag. Sensor response to glucose showed little change over the implant period. Biocompatibility, enzyme lifetime, O2 availability, O2 sensor stability, and biochemical interference were not limitations. Results demonstrated that this sensor can function effectively as an implant in dogs for a period of months and has the potential for long-term operation.

  2. Angioplasty Guided by Intravascular Ultrasound: Meta-Analysis of Randomized Clinical Trials

    Energy Technology Data Exchange (ETDEWEB)

    Figueiredo, José Albuquerque Neto de, E-mail: jafneto@cardiol.br; Nogueira, Iara Antonia Lustosa [Universidade Federal do Maranhão, São Luiz, MA (Brazil); Figueiro, Mabel Fernandes; Buehler, Anna Maria; Berwanger, Otavio [Instituto de Ensino e Pesquisa do Hospital do Coração, São Paulo, SP (Brazil)

    2013-08-15

    The impact of intravascular ultrasound (IVUS) use on stenting has shown inconclusive results. Systematic review and meta-analysis of the impact of IVUS on stenting regarding the clinical and angiographic evolution. A search was performed in Medline/Pubmed, CENTRAL, Embase, Lilacs, Scopus and Web of Science databases. It included randomized clinical trials (RCTs) that evaluated the implantation of stents guided by IVUS, compared with those using angiography alone (ANGIO). The minimum follow-up duration was six months and the following outcomes were assessed: thrombosis, mortality, myocardial infarction, percutaneous and surgical revascularization, major adverse cardiovascular events (MACE) and restenosis. The binary outcomes were presented considering the number of events in each group; the estimates were generated by a random effects model, considering Mantel-Haenszel statistics as weighting agent and magnitude of effect for the relative risk (RR) with its respective 95% confidence interval (95%CI). Higgins I{sup 2} test was used to quantify the consistency between the results of each study. A total of 2,689 articles were evaluated, including 8 RCTs. There was a 27% reduction in angiographic restenosis (RR: 0.73, 95% CI: 0.54-0.97, I{sup 2} = 51%) and statistically significant reduction in the rates of percutaneous revascularization and overall (RR: 0.88; 95% CI: 0.51 to 1.53, I{sup 2} = 61%, RR: 0.73, 95% CI: 0.54 to 0.99, I{sup 2} = 55%), with no statistical difference in surgical revascularization (RR: 0.95, 95% CI: 0.52-1.74, I{sup 2} = 0%) in favor of IVUS vs. ANGIO. There were no differences regarding the other outcomes in the comparison between the two strategies. Angioplasty with stenting guided by IVUS decreases the rates of restenosis and revascularization, with no impact on MACE, acute myocardial infarction, mortality or thrombosis outcomes.

  3. Cryospectrophotometric determination of tumor intravascular oxyhemoglobin saturations: dependence on vascular geometry and tumor growth.

    Science.gov (United States)

    Fenton, B M; Rofstad, E K; Degner, F L; Sutherland, R M

    1988-12-21

    To delineate the complex relationships between overall tumor oxygenation and vascular configuration, intravascular oxyhemoglobin (HbO2) saturation distributions were measured with cryospectrophotometric techniques. Four factors related to vascular morphometry and tumor growth were evaluated: a) vessel diameter, b) distance of vessel from the tumor surface, c) tumor volume, and d) vascular density. To measure intertumor heterogeneity, two murine sarcomas (RIF-1 and KHT) and two human ovarian carcinoma xenografts (OWI and MLS) were utilized. In contrast to skeletal muscle, a preponderance of very low HbO2 saturations was observed for both large and small tumors of all lines. Saturations up to about 90% were also generally present, however, even in very large tumors. Variations in vascular configuration were predominantly tumor-line dependent rather than due to inherent characteristics of the host vasculature, and widely disparate HbO2 distributions were found for alternate lines implanted in identical host mice. Although peripheral saturations remained fairly constant with tumor growth, HbO2 values were markedly lower for vessels nearer the tumor center and further decreased with increasing tumor volume. HbO2 saturations did not change substantially with increasing vascular density (except for KHT tumors), although density did decrease with increasing distance from tumor surface. Combined effects of vessel diameter, tumor volume, and vessel location on HbO2 saturations were complex and varied markedly with both tumor line and vessel class. For specific classes, HbO2 distributions correlated closely with radiobiological hypoxic fractions, i.e., for tumor lines in which hypoxic fraction increased substantially with tumor volume, corresponding HbO2 values decreased, while for lines in which hypoxic fraction remained constant, HbO2 values also were unchanged. Although these trends may also be a function of differing oxygen consumption rates between tumor lines

  4. Intravascular ultrasound evaluation of JETSTREAM atherectomy removal of superficial calcium in peripheral arteries.

    Science.gov (United States)

    Maehara, Akiko; Mintz, Gary S; Shimshak, Thomas M; Ricotta, Joseph J; Ramaiah, Venkatesh; Foster, Malcolm T; Davis, Thomas P; Gray, William A

    2015-05-01

    Endovascular treatment of calcified femoral-popliteal disease is challenging. We sought to evaluate the mechanism of lumen gain when using the JETSTREAM Atherectomy System to treat calcified peripheral artery lesions. The JETSTREAM Calcium Study was a prospective, single-arm, multicentre study to evaluate the JETSTREAM Atherectomy System for severely calcified femoral-popliteal artery lesions, i.e., patients with claudication and lesions with superficial calcium >90° and >5 mm in length as determined by intravascular ultrasound (IVUS). The 2.1 mm catheter was used in this study without distal protection. Fifty-five patients underwent angiographic screening: 26 (45%) met IVUS inclusion criteria. Angiographic calcium was moderate in eight cases and severe in 14, with no available data for four cases. Visual diameter stenosis was 86±9% pre-treatment, 37±13% post atherectomy, and 10±6% post adjunctive treatment (adjunctive PTA+stenting in eight and adjunct PTA alone in 16). IVUS showed lumen area increased from 6.6±3.7 mm2 to 10.0±3.6 mm2 (p=0.001): calcium reduction was responsible for 86±23% of the lumen increase. Although the superficial calcium arc did not change (151±70° to 146±71°, p=0.83), the arc of reverberation increased (23±20° to 65±40°, p=0.006), indicating device-related modification of calcium. Adjunctive balloon angioplasty was performed in 62% of the lesions, and stent implantation in 31%. In 11 cases with adjunctive balloon dilation, the MLA increased from 7.1 (6.4, 7.8) mm2 post atherectomy to 11.9 (10.3, 13.5) mm2 post balloon (pAtherectomy System increased lumen dimensions in moderately or severely calcified femoral-popliteal lesions by removing superficial calcium without major complications.

  5. Gadolinium neutron capture brachytherapy (GdNCB), a new treatment method for intravascular brachytherapy

    International Nuclear Information System (INIS)

    Enger, Shirin A.; Rezaei, Arash; Munck af Rosenschoeld, Per; Lundqvist, Hans

    2006-01-01

    Restenosis is a major problem after balloon angioplasty and stent implantation. The aim of this study is to introduce gadolinium neutron capture brachytherapy (GdNCB) as a suitable modality for treatment of stenosis. The utility of GdNCB in intravascular brachytherapy (IVBT) of stent stenosis is investigated by using the GEANT4 and MCNP4B Monte Carlo radiation transport codes. To study capture rate, Kerma, absorbed dose and absorbed dose rate around a Gd-containing stent activated with neutrons, a 30 mm long, 5 mm diameter gadolinium foil is chosen. The input data is a neutron spectrum used for clinical neutron capture therapy in Studsvik, Sweden. Thermal neutron capture in gadolinium yields a spectrum of high-energy gamma photons, which due to the build-up effect gives an almost flat dose delivery pattern to the first 4 mm around the stent. The absorbed dose rate is 1.33 Gy/min, 0.25 mm from the stent surface while the dose to normal tissue is in order of 0.22 Gy/min, i.e., a factor of 6 lower. To spare normal tissue further fractionation of the dose is also possible. The capture rate is relatively high at both ends of the foil. The dose distribution from gamma and charge particle radiation at the edges and inside the stent contributes to a nonuniform dose distribution. This will lead to higher doses to the surrounding tissue and may prevent stent edge and in-stent restenosis. The position of the stent can be verified and corrected by the treatment plan prior to activation. Activation of the stent by an external neutron field can be performed days after catherization when the target cells start to proliferate and can be expected to be more radiation sensitive. Another advantage of the nonradioactive gadolinium stent is the possibility to avoid radiation hazard to personnel

  6. Determination of Stent Stenosis: An In Vivo Experimental Comparison of Intravascular Ultrasound and Angiography with Histology

    International Nuclear Information System (INIS)

    Schuermann, Karl; Vorwerk, Dierk; Uppenkamp, Robert; Klosterhalfen, Bernd; Buecker, Arno; Guenther, Rolf W.

    1998-01-01

    Purpose: To compare intravascular ultrasound (IVUS) and angiography with histology in determining the degree of stent stenosis in an in vivo experiment. Methods: In 16 sheep, a total of 64 stents were implanted into the external iliac arteries. Two stents were inserted on either side. Patency was followed by angiography and IVUS. Four types of stent were used: two Dacron-covered (Cragg Endopro and heparinized Cragg Endopro) and two non-covered (Cragg and Memotherm stents). Eight animals were killed after 1 month, eight others after 6 months. Histological sections were prepared from the stented vessels. Measurements of the patent and total stent diameters determined by IVUS, angiography, and histology were compared. Results: Correlation between IVUS and angiography was 0.75, between IVUS and histology 0.77, and between angiography and histology 0.85. A mean stent stenosis of 17 ± 11% (range 0-51%) was found on angiography, of 10 ± 11% (0-46%) on IVUS, and of 20 ± 11% (4%-49%) on histology. In comparison with histology, IVUS underestimated the degree of stenosis by 10 ± 8%, and angiography underestimated it by 3 ± 6%. Resolution of IVUS was calculated to be about 0.35 mm and that of angiography to be about 0.15 mm. Conclusion: Under experimental conditions, IVUS was not superior to angiography in determining the degree of stent stenosis in long-segment stenoses of iliac artery stents, when measurements were correlated with histology. Angiography is sufficient for following the patency of iliac artery stents

  7. Hemostasia normal y coagulación intravascular diseminada en obstetricia Normal hemostasis and disseminated intravascular clotting in Obstetrics

    Directory of Open Access Journals (Sweden)

    Danilo Nápoles Méndez

    2012-03-01

    Full Text Available En el período gravido - puerperal, la coagulación sanguínea sufre cambios que se impone conocer para interpretar correctamente esos trastornos cuando se presentan en esta etapa, teniendo en cuenta las posibles complicaciones y el peligro para la vida que pueden presentarse. El objetivo del presente artículo es proporcionar a los obstetras una revisión bibliográfica que les permita actualizarse acerca del tema y facilite su modo de actuación ante pacientes con coagulación intravascular diseminada. Se concluye que es preciso diagnosticar tempranamente el proceso en la fase bioquímica de bajo grado y aplicar en las féminas el tratamiento expedito de la enfermedad de base para eliminar las complicaciones o disminuir su ocurrenciaIn the period from pregnancy to puerperium, blood clotting suffers changes which are important to be known in order to interpret correctly those dysfunctions when they appear in this stage, keeping in mind the possible complications and the danger for life which can take place. The objective of the present work is to provide the obstetricians a literature review that allows them to be updated about the topic and facilitate their performance in case of patients with disseminated intravascular clotting. It is concluded that it is necessary to have an early diagnosis on the process during the low grade biochemical phase and to apply in these women the expedite treatment of the base disease to eliminate complications or to decrease their occurrence.

  8. Cochlear Implants

    Science.gov (United States)

    ... implant, including: • How long a person has been deaf, •The number of surviving auditory nerve fibers, and • ... Implant, Severe Sensoryneurial Hearing Loss Get Involved Professional Development Practice Management ENT Careers Marketplace Privacy Policy Terms ...

  9. Ingeniería de software en el desarrollo de aplicaciones para dispositivos móviles

    OpenAIRE

    Thomas, Pablo Javier; Galdámez, Nicolás; Delía, Lisandro Nahuel; Cristina, Federico; Dapoto, Sebastián H.; Tinetti, Fernando Gustavo; Pesado, Patricia Mabel; De Giusti, Armando Eduardo

    2013-01-01

    Se presenta una línea de investigación y desarrollo que tiene por objeto estudiar temas relacionados con aplicaciones para dispositivos móviles, fundamentalmente aspectos de Ingeniería de Software orientados al desarrollo e implementación de aplicaciones móviles, sobre diversos entornos operativos y el estudio y desarrollo de aspectos de conectividad entre dispositivos móviles.

  10. Mobile bot: Um chatterbot educacional para dispositivos móveis

    Directory of Open Access Journals (Sweden)

    Rony Marcolino Andrade

    2012-11-01

    Full Text Available Os programas que tentam simular diálogos com o ser humano recebem o nome de robôs de conversação ou chatterbots. Ao se utilizar os chatterbots na educação é possível relacionar os alunos e o computador através da linguagem natural, por sua vez o emprego dos chatterbots em dispositivos móveis possibilita a interação do aluno com um agente pedagógico disponível em qualquer lugar e qualquer momento. Nesse sentido, o objetivo desse trabalho é propor o desenvolvimento e avaliação do Mobile bot, um chatterbot educacional para uso em dispositivos móveis com conhecimentos sobre internet.

  11. Una Mirada sobre Dispositivos Móviles de Lecto-Escritura y Visionado

    Directory of Open Access Journals (Sweden)

    Héctor Navarro Güere

    2011-05-01

    Full Text Available Hablar sobre dispositivos móviles para leer y/o visionar hoy es todo un reto. La actualidad y las novedades del mercado imponen una dinámica “artilugio-centrista” y nubla otras perspectivas. El siguiente texto muestra la problemática desde una visión evolutiva y una introducción cognoscitiva. El siguiente análisis parte por la descripción del soporte analógico de la información y la tecnología digital, pasando por la pantalla como interfaz, hasta el estado actual del mercado de los dispositivos móviles de lecto-escritura y tabletas.

  12. Del biopoder al cinepoder en los dispositivos de bioseguridad de la Unión Europea

    Directory of Open Access Journals (Sweden)

    Pedro Torrejón

    2016-09-01

    Full Text Available En pleno siglo XXI, la biomedicina y la biotecnología se han convertido en dos características fundamentales del mundo en el que vivimos. Sin duda, el autor que más se ha trabajado para analizar las repercusiones políticas de estos avances ha sido Michel Foucault a partir de su concepción del biopoder y posteriormente Nikolas Rose al hablar de ethopolítica. Nuestra propuesta afirma que las ideas de ambos sobre lo biótico se engloban en un dispositivo de gestión y administración mayor que lo convierte en una trayectoria o flujo de movimiento, al que denominamos cinepoder. Mediante un estudio de caso de los dispositivos de bioseguridad de la Unión Europea, ilustraremos las características del cinepoder y sus implicaciones sobre el bios.

  13. Local intravascular coagulation and fibrin deposition on intestinal ischemia-reperfusion in rats

    NARCIS (Netherlands)

    Schoots, Ivo G.; Levi, Marcel; Roossink, E. H. Paulina; Bijlsma, Pieter B.; van Gulik, Thomas M.

    2003-01-01

    Background. This study investigates intravascular coagulation and thrombotic obstruction in the splanchnic vasculature after intestinal ischemia in relation to epithelial integrity and function. Methods. Intestinal ischemia was induced in rats by superior mesenteric artery occlusion for 20 or 40

  14. Intravascular radiation for restenosis prevention: could it be the holy grail?

    International Nuclear Information System (INIS)

    King, S.B.

    1996-01-01

    This brief editorial discusses the use of intravascular radiation in preventing restenosis after angioplasty in coronary interventions. Results in porcine coronary arteries and clinical applications are briefly reported. (UK)

  15. New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology

    NARCIS (Netherlands)

    Levi, Marcel; de Jonge, Evert; van der Poll, Tom

    2004-01-01

    A variety of clinical conditions may cause systemic activation of coagulation, ranging from insignificant laboratory changes to severe disseminated intravascular coagulation (DIC). DIC consists of a widespread, systemic activation of coagulation, resulting in diffuse fibrin deposition in small and

  16. Cutaneous and systemic hypersensitivity reactions to metallic implants

    DEFF Research Database (Denmark)

    Basko-Plluska, Juliana L; Thyssen, Jacob P; Schalock, Peter C

    2011-01-01

    ) following the insertion of intravascular stents, dental implants, cardiac pacemakers, or implanted gynecologic devices. Despite repeated attempts by researchers and clinicians to further understand this difficult area of medicine, the association between metal sensitivity and cutaneous allergic reactions......Cutaneous reactions to metal implants, orthopedic or otherwise, are well documented in the literature. The first case of a dermatitis reaction over a stainless steel fracture plate was described in 1966. Most skin reactions are eczematous and allergic in nature, although urticarial, bullous......, and vasculitic eruptions may occur. Also, more complex immune reactions may develop around the implants, resulting in pain, inflammation, and loosening. Nickel, cobalt, and chromium are the three most common metals that elicit both cutaneous and extracutaneous allergic reactions from chronic internal exposure...

  17. A AUTORIA, O DISPOSITIVO E A ÉTICA: OS LIMITES DA (DESSUBJETIVAÇÃO NA ESCRITA

    Directory of Open Access Journals (Sweden)

    Atilio BUTTURI JUNIOR

    Full Text Available RESUMO Este texto tem como objetivo oferecer uma releitura do conceito de autoria de Michel Foucault, definido e comentado a partir de três textos fundamentais: A Arqueologia do Saber, O que é um autor? e A Ordem do Discurso. A hipótese é de que a autoria pode ser lida como um dispositivo – o dispositivo da autoria ou autoral – e que, dessa perspectiva, pode ser problematizado a partir do conceito de resistência e da preocupação ética do chamado “último Foucault”. Para defender tal hipótese, recorre-se inicialmente à descrição do conceito do dispositivo e do conceito de autoria, na arqueogenealogia e segundo alguns comentadores. Depois, traça-se uma discussão entre o dispositivo da autoria e as possibilidades de resistência e de criação subjetiva, presentes em conceitos como epimeleia heautou, crítica ou dessubjetivação. Por fim, sugere-se que o dispositivo da autoria pode ser lido ainda foucaultianamente, desde que segundo a ordem de uma política e de uma luta agonística entre os viventes e os dispositivos.

  18. 78. Asistencia biventricular de larga duración mediante dispositivo heartware hvad miniaturizado

    Directory of Open Access Journals (Sweden)

    M.T. González López

    2012-04-01

    Conclusiones: Existe una limitada experiencia a nivel mundial con el empleo de asistencia de flujo continuo en el corazón derecho. Sin embargo, este tipo de dispositivo permite una técnica relativamente sencilla de implantación, junto con una mayor autonomía y calidad de vida del paciente que precisa soporte biventricular de larga duración como puente al trasplante.

  19. The Incidence of Intravascular Needle Entrance during Inferior Alveolar Nerve Block Injection.

    Science.gov (United States)

    Taghavi Zenouz, Ali; Ebrahimi, Hooman; Mahdipour, Masoumeh; Pourshahidi, Sara; Amini, Parisa; Vatankhah, Mahdi

    2008-01-01

    Dentists administer thousands of local anesthetic injections every day. Injection to a highly vascular area such as pterygomandibular space during an inferior alveolar nerve block has a high risk of intravascular needle entrance. Accidental intravascular injection of local anesthetic agent with vasoconstrictor may result in cardiovascular and central nervous system toxicity, as well as tachycardia and hypertension. There are reports that indicate aspiration is not performed in every injection. The aim of the present study was to assess the incidence of intravascular needle entrance in inferior alveolar nerve block injections. Three experienced oral and maxillofacial surgeons performed 359 inferior alveolar nerve block injections using direct or indirect techniques, and reported the results of aspiration. Aspirable syringes and 27 gauge long needles were used, and the method of aspiration was similar in all cases. Data were analyzed using t-test. 15.3% of inferior alveolar nerve block injections were aspiration positive. Intravascular needle entrance was seen in 14.2% of cases using direct and 23.3% of cases using indirect block injection techniques. Of all injections, 15.8% were intravascular on the right side and 14.8% were intravascular on the left. There were no statistically significant differences between direct or indirect block injection techniques (P = 0.127) and between right and left injection sites (P = 0.778). According to our findings, the incidence of intravascular needle entrance during inferior alveolar nerve block injection was relatively high. It seems that technique and maneuver of injection have no considerable effect in incidence of intravascular needle entrance.

  20. The Incidence of Intravascular Needle Entrance during Inferior Alveolar Nerve Block Injection

    Directory of Open Access Journals (Sweden)

    Sara Pourshahidi

    2008-04-01

    Full Text Available

    Background and aims. Dentists administer thousands of local anesthetic injections every day. Injection to a highly vascular area such as pterygomandibular space during an inferior alveolar nerve block has a high risk of intravascular needle entrance. Accidental intravascular injection of local anesthetic agent with vasoconstrictor may result in cardiovascular and central nervous system toxicity, as well as tachycardia and hypertension. There are reports that indicate aspiration is not performed in every injection. The aim of the present study was to assess the incidence of intravascular needle entrance in inferior alveolar nerve block injections.

    Materials and methods. Three experienced oral and maxillofacial surgeons performed 359 inferior alveolar nerve block injections using direct or indirect techniques, and reported the results of aspiration. Aspirable syringes and 27 gauge long needles were used, and the method of aspiration was similar in all cases. Data were analyzed using t-test.

    Results. 15.3% of inferior alveolar nerve block injections were aspiration positive. Intravascular needle entrance was seen in 14.2% of cases using direct and 23.3% of cases using indirect block injection techniques. Of all injections, 15.8% were intravascular on the right side and 14.8% were intravascular on the left. There were no statistically significant differences between direct or indirect block injection techniques (P = 0.127 and between right and left injection sites (P = 0.778.

    Conclusion. According to our findings, the incidence of intravascular needle entrance during inferior alveolar nerve block injection was relatively high. It seems that technique and maneuver of injection have no considerable effect in incidence of intravascular needle entrance.

  1. Gallium SPECT detection of neoplastic intravascular obstruction of the superior vena cava

    International Nuclear Information System (INIS)

    Swayne, L.C.; Kaplan, I.L.

    1989-01-01

    A rare case of an intravascular neoplastic obstruction of the superior vena cava is discussed. The lesion was detected with gallium single photon emission computed tomography (SPECT) despite a normal appearance on a concurrent radiographic CT study. A computer-generated composite SPECT-CT image confirmed the intravascular localization of the radioisotope, and a subsequent CT-guided transthoracic needle biopsy revealed a poorly differentiated adenocarcinoma

  2. Uso de los dispositivos móviles en educación infantil

    Directory of Open Access Journals (Sweden)

    Javier Fombona

    2016-11-01

    Full Text Available Este trabajo analiza la eficacia en la gestión del conocimiento apoyado con dispositivos móviles en el ámbito de la Educación Infantil y propone pautas para introducir esta herramienta desde la perspectiva del b-learning. La investigación tiene un carácter descriptivo y aborda cómo las distintas formas de aprendizaje apoyadas con recursos electrónicos se están convirtiendo en nuevos modelos de enseñanza. También se analizan los efectos en el rendimiento escolar tras incorporar dispositivos móviles en el desarrollo de un tema, apoyado por el docente y la familia. Los resultados analizados son de tipo gráfico, e indican que los alumnos de 4 o 5 años también pueden manejar estos equipos digitales móviles en un proceso de enseñanza y aprendizaje con cierta autonomía. El hecho de implicar a las familias favorece la propia formación de los niños a lo largo de la jornada, deslocalizando espacialmente la zona formativa, dando una utilidad educativa a estos dispositivos.

  3. Effector CD4+ T cells recognize intravascular antigen presented by patrolling monocytes.

    Science.gov (United States)

    Westhorpe, Clare L V; Norman, M Ursula; Hall, Pam; Snelgrove, Sarah L; Finsterbusch, Michaela; Li, Anqi; Lo, Camden; Tan, Zhe Hao; Li, Songhui; Nilsson, Susan K; Kitching, A Richard; Hickey, Michael J

    2018-02-21

    Although effector CD4 + T cells readily respond to antigen outside the vasculature, how they respond to intravascular antigens is unknown. Here we show the process of intravascular antigen recognition using intravital multiphoton microscopy of glomeruli. CD4 + T cells undergo intravascular migration within uninflamed glomeruli. Similarly, while MHCII is not expressed by intrinsic glomerular cells, intravascular MHCII-expressing immune cells patrol glomerular capillaries, interacting with CD4 + T cells. Following intravascular deposition of antigen in glomeruli, effector CD4 + T-cell responses, including NFAT1 nuclear translocation and decreased migration, are consistent with antigen recognition. Of the MHCII + immune cells adherent in glomerular capillaries, only monocytes are retained for prolonged durations. These cells can also induce T-cell proliferation in vitro. Moreover, monocyte depletion reduces CD4 + T-cell-dependent glomerular inflammation. These findings indicate that MHCII + monocytes patrolling the glomerular microvasculature can present intravascular antigen to CD4 + T cells within glomerular capillaries, leading to antigen-dependent inflammation.

  4. MRI phenotypes of localized intravascular coagulopathy in venous malformations

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Kevin S.H. [Boston Children' s Hospital, Department of Radiology, Boston, MA (United States); Dowd, Christopher F.; Hess, Christopher P. [University of California, San Francisco, Department of Radiology and Biomedical Imaging, San Francisco, CA (United States); Mathes, Erin F.; Frieden, Ilona J. [University of California, San Francisco, Department of Dermatology, San Francisco, CA (United States); Rosbe, Kristina W. [University of California, San Francisco, Department of Otolaryngology, San Francisco, CA (United States); Hoffman, William Y. [University of California, San Francisco, Department of Surgery, San Francisco, CA (United States)

    2015-10-15

    The incidence of localized intravascular coagulopathy (LIC) in venous malformations varies with lesion size and location, as well as the presence of palpable phleboliths. The development of LIC can cause pain and hemorrhage and can progress to disseminated intravascular coagulopathy (DIC) and thromboembolic disease resulting in death in some cases. Early recognition of LIC can relieve symptoms and prevent progression to life-threatening complications. The aim of this work was to identify MRI features of venous malformation associated with LIC. We hypothesized that venous malformations with larger capacitance, slower flow and less physiological compression (greater stasis) were more likely to be associated with LIC. In this HIPAA-compliant and IRB-approved study, we retrospectively reviewed clinical records and MRI for consecutive patients undergoing evaluation of venous malformations at our multidisciplinary Birthmarks and Vascular Anomalies Center between 2003 and 2013. Inclusion required consensus diagnosis of venous malformation and availability of laboratory data and MRI; patients on anticoagulation or those previously undergoing surgical or endovascular treatment were excluded. LIC was diagnosed when D-dimer exceeded 1,000 ng/mL and/or fibrinogen was less than 200 mg/dL. Two board-certified radiologists assessed the following MRI features for each lesion: morphology (spongiform vs. phlebectatic), presence of phleboliths, size, location (truncal vs. extremity), and tissue type(s) involved (subcutis, muscle, bone and viscera). Univariate logistic regression analyses were used to test associations between LIC and MRI findings, and stepwise regression was applied to assess the significance of the individual imaging predictors. Seventy patients, 37 with LIC, met inclusion criteria during the 10-year study period (age: 14.5 +/- 13.6 years [mean +/- standard deviation]; 30 male, 40 female). Both elevated D-dimer and low fibrinogen were associated with the presence of

  5. MRI phenotypes of localized intravascular coagulopathy in venous malformations

    International Nuclear Information System (INIS)

    Koo, Kevin S.H.; Dowd, Christopher F.; Hess, Christopher P.; Mathes, Erin F.; Frieden, Ilona J.; Rosbe, Kristina W.; Hoffman, William Y.

    2015-01-01

    The incidence of localized intravascular coagulopathy (LIC) in venous malformations varies with lesion size and location, as well as the presence of palpable phleboliths. The development of LIC can cause pain and hemorrhage and can progress to disseminated intravascular coagulopathy (DIC) and thromboembolic disease resulting in death in some cases. Early recognition of LIC can relieve symptoms and prevent progression to life-threatening complications. The aim of this work was to identify MRI features of venous malformation associated with LIC. We hypothesized that venous malformations with larger capacitance, slower flow and less physiological compression (greater stasis) were more likely to be associated with LIC. In this HIPAA-compliant and IRB-approved study, we retrospectively reviewed clinical records and MRI for consecutive patients undergoing evaluation of venous malformations at our multidisciplinary Birthmarks and Vascular Anomalies Center between 2003 and 2013. Inclusion required consensus diagnosis of venous malformation and availability of laboratory data and MRI; patients on anticoagulation or those previously undergoing surgical or endovascular treatment were excluded. LIC was diagnosed when D-dimer exceeded 1,000 ng/mL and/or fibrinogen was less than 200 mg/dL. Two board-certified radiologists assessed the following MRI features for each lesion: morphology (spongiform vs. phlebectatic), presence of phleboliths, size, location (truncal vs. extremity), and tissue type(s) involved (subcutis, muscle, bone and viscera). Univariate logistic regression analyses were used to test associations between LIC and MRI findings, and stepwise regression was applied to assess the significance of the individual imaging predictors. Seventy patients, 37 with LIC, met inclusion criteria during the 10-year study period (age: 14.5 +/- 13.6 years [mean +/- standard deviation]; 30 male, 40 female). Both elevated D-dimer and low fibrinogen were associated with the presence of

  6. Heartbeat OCT: in vivo intravascular megahertz-optical coherence tomography

    Science.gov (United States)

    Wang, Tianshi; Pfeiffer, Tom; Regar, Evelyn; Wieser, Wolfgang; van Beusekom, Heleen; Lancee, Charles T.; Springeling, Geert; Krabbendam, Ilona; van der Steen, Antonius F.W.; Huber, Robert; van Soest, Gijs

    2015-01-01

    Cardiac motion artifacts, non-uniform rotational distortion and undersampling affect the image quality and the diagnostic impact of intravascular optical coherence tomography (IV-OCT). In this study we demonstrate how these limitations of IV-OCT can be addressed by using an imaging system that we called “Heartbeat OCT”, combining a fast Fourier Domain Mode Locked laser, fast pullback, and a micromotor actuated catheter, designed to examine a coronary vessel in less than one cardiac cycle. We acquired in vivo data sets of two coronary arteries in a porcine heart with both Heartbeat OCT, working at 2.88 MHz A-line rate, 4000 frames/s and 100 mm/s pullback speed, and with a commercial system. The in vivo results show that Heartbeat OCT provides faithfully rendered, motion-artifact free, fully sampled vessel wall architecture, unlike the conventional IV-OCT data. We present the Heartbeat OCT system in full technical detail and discuss the steps needed for clinical translation of the technology. PMID:26713214

  7. A Micromotor Catheter for Intravascular Optical Coherence Tomography

    Directory of Open Access Journals (Sweden)

    Tianshi Wang

    2015-03-01

    Full Text Available We have developed a new form of intravascular optical coherence tomography (IV-OCT that allows the extremely fast acquisition of high-resolution images of the coronary arteries. This process leads to much better image quality by eliminating cardiac motion artefacts and undersampling. It relies on a catheter that incorporates a synchronous micromotor with a diameter of 1.0 mm and a rotational speed of up to 5600 revolutions per second, enabling an IV-OCT frame rate of 5.6 kHz. This speed is matched by a wavelength-swept laser that generates up to 2.8 million image lines per second. With this setup, our team achieved IV-OCT imaging of up to 5600 frames per second (fps in vitro and 4000 fps in vivo, deployed at a 100 mm·s−1 pullback velocity. The imaging session is triggered by the electrocardiogram of the subject, and can scan a coronary artery in the phase of the heartbeat where the heart is at rest, providing a name for this new technology: the “Heartbeat OCT.”

  8. Intravascular trans-catheter fibrinolysis in acute arterial obstructions

    International Nuclear Information System (INIS)

    Roversi, R.; Rossi, C.; Ricci, S.; Gemelli, G.; Ciliberti, M.A.

    1987-01-01

    The author's experiences is reported on intravascular fibrinolytic therapy with urokinase in acute arterial obstructions. Thirty-eight patients were treated, from 1983 to 1986, for acute thrombosis and/or thromboembolization, 22 of which developed on an atherosclerotic lesion, and 10 on a surgical stenotic by-pass graft. A complete vascular recanalization has been obtained, at the end of the procedure, in 69,4% of the cases, 77,7% had a definite final clinical improvement. The results correspond to the medium statistical of the various casistics analyzed for comparison. Surgery has been performed on 27,7% of the patients. Complication have been observed in 8% of the cases. IAF technique is of greatest value in the treatment of those lesions; better results have been obtained with intra-thrombus injection of the drug (as emphasized by many authors) in association with PTA and surgery. A close cooperation between interventional radiology, vascular surgery and angiology is therefore necessary in this field

  9. Primary intravascular large B-cell lymphoma of pituitary

    Directory of Open Access Journals (Sweden)

    K R Anila

    2012-01-01

    Full Text Available A 68-year-old retired nurse, who was a known hypertensive on medication, presented with prolonged fever of 2-month duration without any clinical evidence of infection. On examination she had altered mental status. She also had other nonspecific complaints such as sleep disturbances, loss of weight, etc. On investigation, she was found to have anemia, thrombocytopenia, raised erythrocyte sedimentation rate (ESR, C-reactive protein (CRP, and lactate dehydrogenase (LDH values. She also had electrolyte imbalance. Radiological evaluation of brain showed mass lesion in the sella turcica, suggestive of pituitary adenoma. Biochemical evaluation showed hypopituitarism. Trans-sphenoidal biopsy was done. Based on histopathological and immunohistochemical findings a diagnosis of intravascular large B-cell lymphoma (IVLBCL of pituitary was made. Our patient′s condition deteriorated rapidly and she succumbed to her illness before therapy could be initiated. We are reporting this case because of the rare subtype of large B-cell lymphoma presenting at an extremely unusual primary site.

  10. Intravascular ultrasound based dose assessment in endovascular brachytherapy

    International Nuclear Information System (INIS)

    Catalano, Gianpiero; Tamburini, Vittorio; Colombo, Antonio; Nishida, Takahiro; Parisi, Giovanni; Mazzetta, Chiara; Orecchia, Roberto

    2003-01-01

    Background: the role of endovascular brachytherapy in restenosis prevention is well documented. Dose is usually prescribed at a fixed distance from the source axis by angiographic quantification of vessel diameter. Recently, intravascular ultrasound (IVUS) was introduced in dose prescription, allowing a better evaluation of the vessel anatomy. This study retrospectively explores the difference between prescription following angiographic vessel sizing and delivered dose calculated with IVUS. Methods and results: Seventeen lesions were studied with IVUS, identifying on irradiated segment, three sections on which measuring minimal and maximal distance from the centre of IVUS catheter to the adventitia; using dedicated software, corresponding doses were calculated. The dose ranged widely, with maximal and minimal values of 71.6 and 4.9 Gy; furthermore, heterogeneity in dose among different sections was observed. In the central section, the maximal dose was 206% of the one prescribed with the QCA model at 2 mm from the source axis, while the minimal dose was 96%. In proximal and distal sections, respective values were 182, 45, 243, and 122%. Conclusions: Our analysis confirmed the dose inhomogeneity delivered with an angiographic fixed-dose prescription strategy. A dose variation was found along the irradiated segment due to the differences in vessel thickness. IVUS emerged as an important tool in endovascular brachytherapy, especially for irregular-shaped vessels

  11. Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies: a report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

    DEFF Research Database (Denmark)

    Falk, Erling

    2012-01-01

    The purpose of this document is to make the output of the International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available to medical and scientific communities, through a peer-reviewed publication, in the interest of improving...

  12. Consensus standards for acquisition, measurement, and reporting of intravascular optical coherence tomography studies : A report from the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

    NARCIS (Netherlands)

    G.J. Tearney (Guillermo); E.S. Regar (Eveline); T. Akasaka (Takashi); S. Adriaenssens (Stef); P. Barlis (Peter); H.G. Bezerra (Hiram); B.E. Bouma (Brett); N. Bruining (Nico); J.-M. Cho (Jin-Man); S. Chowdhary (Saqib); M.A. Costa (Marco); R. de Silva (Ranil); J. Dijkstra (Jouke); C. di Mario (Carlo); D. Dudeck (Darius); E. Falk (Erling); M.D. Feldman (Marc); P.J. Fitzgerald (Peter); H.M. Garcia-Garcia (Hector); N. Gonzalo (Nieves); J.F. Granada (Juan); G. Guagliumi (Giulio); N.R. Holm (Niels); Y. Honda (Yasuhiro); F. Ikeno (Fumiaki); Y. Kawasaki; W. Kochman (Waclav); L. Koltowski (Lukasz); T. Kubo (Takashi); T. Kume (Teruyoshi); H. Kyono (Hiroyuki); C.C.S. Lam (Cheung Chi Simon); G. Lamouche (Guy); D.P. Lee (David); M.B. Leon (Martin); A. Maehara (Akiko); O. Manfrini (Olivia); G.S. Mintz (Gary); K. Mizuno (Kyiouchi); M-A.M. Morel (Marie-Angèle); S. Nadkarni (Seemantini); H. Okura (Hiroyuki); H. Otake (Hiromasa); A. Pietrasik (Arkadiusz); F. Prati (Francesco); L. Rber (Lorenz); M. Radu (Maria); N. Rieber (Nikolaus); M. Riga (Maria); S.M. Rollins; M. Rosenberg (Mireille); V. Sirbu (Vasile); P.W.J.C. Serruys (Patrick); K. Shimada; T. Shinke (Toshiro); J. Shite (Junya); E. Siegel (Eliot); S. Sonada (Shinjo); U. Suter (Ueli); S. Takarada (Shigeho); A. Tanaka (Atsushi); M. Terashima (Mitsuyasu); T. Troels (Thim); M. Uemura (Mayu); G.J. Ughi (Giovanni); H.M.M. van Beusekom (Heleen); A.F.W. van der Steen (Ton); G.A. van Es (Gerrit Anne); G. van Soest (Gijs); R. Virmani (Renu); S. Waxman (Sergio); N.J. Weissman (Neil); G. Weisz (Giora)

    2012-01-01

    textabstractObjectives: The purpose of this document is to make the output of the International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available to medical and scientific communities, through a peer-reviewed publication, in the

  13. Imminent Cardiac Risk Assessment via Optical Intravascular Biochemical Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Wetzel, D.; Wetzel, L; Wetzel, M; Lodder, R

    2009-01-01

    Heart disease is by far the biggest killer in the United States, and type II diabetes, which affects 8% of the U.S. population, is on the rise. In many cases, the acute coronary syndrome and/or sudden cardiac death occurs without warning. Atherosclerosis has known behavioral, genetic and dietary risk factors. However, our laboratory studies with animal models and human post-mortem tissue using FT-IR microspectroscopy reveal the chemical microstructure within arteries and in the arterial walls themselves. These include spectra obtained from the aortas of ApoE-/- knockout mice on sucrose and normal diets showing lipid deposition in the former case. Also pre-aneurysm chemical images of knockout mouse aorta walls, and spectra of plaque excised from a living human patient are shown for comparison. In keeping with the theme of the SPEC 2008 conference Spectroscopic Diagnosis of Disease this paper describes the background and potential value of a new catheter-based system to provide in vivo biochemical analysis of plaque in human coronary arteries. We report the following: (1) results of FT-IR microspectroscopy on animal models of vascular disease to illustrate the localized chemical distinctions between pathological and normal tissue, (2) current diagnostic techniques used for risk assessment of patients with potential unstable coronary syndromes, and (3) the advantages and limitations of each of these techniques illustrated with patent care histories, related in the first person, by the physician coauthors. Note that the physician comments clarify the contribution of each diagnostic technique to imminent cardiac risk assessment in a clinical setting, leading to the appreciation of what localized intravascular chemical analysis can contribute as an add-on diagnostic tool. The quality of medical imaging has improved dramatically since the turn of the century. Among clinical non-invasive diagnostic tools, laboratory tests of body fluids, EKG, and physical examination are

  14. Intravascular papillary endothelial hyperplasia: magnetic resonance imaging of finger lesions

    Energy Technology Data Exchange (ETDEWEB)

    Sung, Jinkyeong; Kim, Jee-Young [The Catholic University of Korea, Department of Radiology, St. Vincent' s Hospital, College of Medicine, Suwon, Gyeonggi-do (Korea, Republic of); Yoo, Changyoung [The Catholic University of Korea, Department of Hospital Pathology, St. Vincent' s Hospital, College of Medicine, Suwon, Gyeonggi-do (Korea, Republic of)

    2016-02-15

    To describe magnetic resonance imaging (MRI) features of intravascular papillary endothelial hyperplasia (IPEH), to identify findings differentiating IPEH of the finger from that of other locations, and to correlate these with pathology. Nineteen patients with 20 I.E. masses of the finger (n = 13) and other locations (n = 7) were evaluated. All patients underwent MRI, and the results were correlated with pathology. Seventeen IPEHs, including all IPEHs of the finger, were located in the subcutis, the three other lesions in the muscle layer. On T1WI, all masses were isointense or slightly hyperintense. IPEHs of the finger (n = 13) revealed focal hyperintense nodules (n = 2) or central hypointensity (n = 2) on T1WI, hypointensity with a hyperintense rim (n = 7), hyperintensity with hypointense nodules (n = 5), or isointensity with a hypointense rim (n = 1) on T2WI, and rim enhancement (n = 5), heterogeneous enhancement with nodular nonenhanced areas (n = 6), peripheral nodular enhancement (n = 1), or no enhancement (n = 1) on gadolinium-enhanced T1WI. IPEHs of other locations (n = 7) demonstrated focal hyperintense nodules (n = 5) on T1WI, hyperintensity with hypointense nodules (n = 5) or heterogeneous signal intensity (n = 2) on T2WI, and rim or rim and septal enhancement (n = 6) or peripheral nodular enhancement (n = 1). Microscopically, IPEHs were composed of thrombi that were hypointense on T2WI and papillary endothelial proliferations that showed T2 hyperintensity and enhancement. MRI of finger IPEH reveals well-demarcated subcutaneous masses with hypointensity or hypointense nodules with peripheral hyperintensity on T2WI, as well as peripheral enhancement. T1 hyperintense nodules, internal heterogeneity on T2WI, and septal enhancement are more common in IPEH of other locations. (orig.)

  15. ARCOCT: Automatic detection of lumen border in intravascular OCT images.

    Science.gov (United States)

    Cheimariotis, Grigorios-Aris; Chatzizisis, Yiannis S; Koutkias, Vassilis G; Toutouzas, Konstantinos; Giannopoulos, Andreas; Riga, Maria; Chouvarda, Ioanna; Antoniadis, Antonios P; Doulaverakis, Charalambos; Tsamboulatidis, Ioannis; Kompatsiaris, Ioannis; Giannoglou, George D; Maglaveras, Nicos

    2017-11-01

    Intravascular optical coherence tomography (OCT) is an invaluable tool for the detection of pathological features on the arterial wall and the investigation of post-stenting complications. Computational lumen border detection in OCT images is highly advantageous, since it may support rapid morphometric analysis. However, automatic detection is very challenging, since OCT images typically include various artifacts that impact image clarity, including features such as side branches and intraluminal blood presence. This paper presents ARCOCT, a segmentation method for fully-automatic detection of lumen border in OCT images. ARCOCT relies on multiple, consecutive processing steps, accounting for image preparation, contour extraction and refinement. In particular, for contour extraction ARCOCT employs the transformation of OCT images based on physical characteristics such as reflectivity and absorption of the tissue and, for contour refinement, local regression using weighted linear least squares and a 2nd degree polynomial model is employed to achieve artifact and small-branch correction as well as smoothness of the artery mesh. Our major focus was to achieve accurate contour delineation in the various types of OCT images, i.e., even in challenging cases with branches and artifacts. ARCOCT has been assessed in a dataset of 1812 images (308 from stented and 1504 from native segments) obtained from 20 patients. ARCOCT was compared against ground-truth manual segmentation performed by experts on the basis of various geometric features (e.g. area, perimeter, radius, diameter, centroid, etc.) and closed contour matching indicators (the Dice index, the Hausdorff distance and the undirected average distance), using standard statistical analysis methods. The proposed method was proven very efficient and close to the ground-truth, exhibiting non statistically-significant differences for most of the examined metrics. ARCOCT allows accurate and fully-automated lumen border

  16. Estudio de adaptabilidad para dispositivos móviles en plataformas MOOC

    Directory of Open Access Journals (Sweden)

    Francisco Brazuelo Grund

    2015-01-01

    Full Text Available Los MOOC ( Massive Open Online Courses constituyen una modalidad de educación a distancia , reciente , pero con un importante impacto y extensión, especialmente en el ámbito de las instituciones universitarias. Su s principios, enraizados en el conectivismo, permite n un acceso gratuito y abierto a contenidos educativos, fomentando la universalización de la educación y la formación continua. Su difusión se basa en cursos alojados en plataforma s de aprendizaje online y, en parte considerable, el acceso se realiza desde dispositivos móviles. El estudio descriptivo , que a con tinuación se presenta , ha implicado el análisis de 22 plataformas MOOC, nacionales e internacionales, con el propósito de conocer su grado de adaptabilidad ubicua y portable para dispositivos móviles , entre los que se destacan smartphones, phablets y table tas digitales bajo los criterios de visibilidad en pantallas de dispositivos móviles, capacidad responsiva de los contenidos y existencia de versión en forma de App o aplicación móvil . Los resultados muestran limitaciones en la adaptación móvil de plataformas MOOC que condicionan su visib ilidad y, por tanto, plantea la necesidad de una redefinición de los procesos iniciales de diseño , y por ende de sus contenidos, según los principios del Mobile Learning o Aprendizaje Móvil con la finalidad de acomo dar estos cursos a los contextos reales de aprendizaje de los usuarios en situaciones de movilidad.

  17. Epub (Versión Completa para Tablet y Dispositivos Móviles

    Directory of Open Access Journals (Sweden)

    Revista Epub

    2013-11-01

    Full Text Available Este es la versión electrónica para tablets y dispositivos móbiles de la Revista Calle14 Vol 7 No 9 Revista de investigación en el campo del arte.Usted podrá descargar esta versión E PUB y guardarla en su biblioteca personal. Para descargar el archivo EPUB, consultar el siguiente enlace de SlideShare:http://www.slideshare.net/dimarc/como-descargar-un-archivo-epub-de-la-revista-28209496

  18. Estudio de dispositivos magnetométricos : aplicación al Proyecto NANOSAT

    OpenAIRE

    Díaz Michelena, Marina

    2004-01-01

    Se han estudiado, diseñado y desarrollado, con éxito, varios tipos de sensores magnéticos basados en distintos principios: método de fuerzas, efectos cruzados, magnetorresistencia anisotrópica, efectos magneto-ópticos y optoelectrónica, con aplicaciones magnetométricas diferentes: fundamentalmente medidas de momento y de campo magnético. Estos sensores constituyen una aportación a los dispositivos microtecnológicos de caracterización magnética. Dentro de este ámbito se ha trabajado en tres lí...

  19. Control del brazo robot IRB120 mediante el dispositivo háptico PHANTOM

    OpenAIRE

    Pardo Alía, Samuel

    2016-01-01

    El proyecto expuesto en el presente libro consiste en el control del brazo robot IRB120 a través de diferentes aplicaciones por medio de una interfaz gráfica creada con el software matemático MATLAB. Todo ello se llevará a cabo gracias a un socket de comunicación desarrollado en lenguaje RAPID que permite el envío simultáneo de varias posiciones al robot. Entre esas aplicaciones destaca el empleo del dispositivo háptico Phantom Omni para la creación de dibujos o textos a man...

  20. SISCI - SISTEMA PARA CONTROLE DE IRRIGAÇÃO ATRAVÉS DE DISPOSITIVOS CELULARES

    OpenAIRE

    Costa, Clayton Maciel; Fernandes, Islame Felipe; Almeida, Leandro Ismael

    2012-01-01

    O advento das tecnologias de informação, a expansão da Web e as modernas necessidades de mobilidade e compartilhamento de dados tiveram como resultado o investimento em sistemas adequados a dispositivos móveis, como o aparelho celular. Entretanto, utilização dessas tecnologias para otimização de processos pertinentes à área agrícola é pouco utilizada, e o desenvolvimento do projeto SisCI baseia-se nessa necessidade. Esse projeto trata-se do desenvolvimento de um sistema de tempo real para o ...

  1. Agentes java para dispositivos móviles con conexión bluetooth

    OpenAIRE

    Royo, José Alberto; Mena Nieto, Eduardo; Acero, Roberto

    2009-01-01

    La tecnología de agentes móviles cobra especial importancia en entornos inalámbricos, donde la computación y los recursos en general pueden levarse allá donde sean necesarios. Sin embargo, actualmente existe un salto tecnológico entre los requerimientos software de una plataforma de agentes móviles y las prestaciones de los dispositivos móviles actuales, incluso los PDAs (Personal Data Assistant) más avanzados. Entre los problemas a resolver podemos citar los protocolos de comunicación inalám...

  2. DACTA : Dispositivo de Apoyo Académico por Tareas Autoadministradas. Inglés 1

    OpenAIRE

    Simón, Liliana; Stamboni, Juan Luis

    1999-01-01

    La Facultad de Humanidades y Ciencias de la Educación de la Universidad Nacional de la Plata inicia la publicación de la serie DACTA, Dispositivo de Apoyo Académico por Tareas Autoadministrado, en el marco de un conjunto de estrategias de mejoramiento de la calidad educativa y desarrollo de proyectos innovadores. Este libro acompaña a los alumnos ingresantes a las carreras del Profesorado, Traductorado y Licenciaturas de las carreras de inglés de la FAHCE, UNLP.

  3. Sistema de reconocimiento facial y realidad aumentada para dispositivos móviles

    OpenAIRE

    Martínez Pérez, Juan Vicente; Linares Pellicer, Jordi Joan

    2012-01-01

    [EN] The aim of thispaperistoexplaintheproblems of using facial recognition featuresontoday¿s Mobile devices and provide a possiblesolutionbasedon a client-server design. [ES] El objetivo de este artículo es explicar la problemática de utilizar las funciones de reconocimiento facial en los dispositivos móviles actuales, así como dar una posible solución basándonos en un diseño cliente-servidor. Martínez Pérez, JV.; Linares Pellicer, JJ. (2012). Sistema de reconocimiento facial y rea...

  4. “ANDROID” EL SISTEMA OPERATIVO DE GOOGLE PARA DISPOSITIVOS MÓVILES

    Directory of Open Access Journals (Sweden)

    Kristel Malave Polanco

    2011-07-01

    Full Text Available El objetivo de este artículo consiste en ofrecerle al lector la posibilidad de conocer la influencia del sistema operativo Android en el mundo de los dispositivos móviles inteligentes. La investigación es de carácter documental, y se realizaron encuestas y entrevistas que buscan como resultado emitir conclusiones acerca de las incidencias y ventajas que ofrece este sistema operativo , logrando identificar las características principales que lo convierten en una alternativa para los fabricantes de smartphones y sus usuarios, a pesar del poco tiempo desde su aparición.

  5. Úlceras por presión causadas por dispositivos clínicos

    OpenAIRE

    Iglesias Ruisánchez, Sandra

    2017-01-01

    Las úlceras por presión (UPP) son lesiones comunes en los pacientes hospitalizados, especialmente en las unidades de cuidados intensivos (UCI). Los enfermos críticos tienen un riesgo elevado de desarrollar UPP, debido principalmente a la limitación de la movilidad, disminuyendo su capacidad para cambiar activamente su posición en la cama o asiento. Además, el efecto de fármacos anestésicos y sedantes, puede causar una pérdida de la percepción sensorial cutánea. Los diferentes dispositivos clí...

  6. Ion implantation

    International Nuclear Information System (INIS)

    Johnson, E.

    1986-01-01

    It is the purpose of the present paper to give a review of surface alloy processing by ion implantation. However, rather than covering this vast subject as a whole, the survey is confined to a presentation of the microstructures that can be found in metal surfaces after ion implantation. The presentation is limited to alloys processed by ion implantation proper, that is to processes in which the alloy compositions are altered significantly by direct injection of the implanted ions. The review is introduced by a presentation of the processes taking place during development of the fundamental event in ion implantation - the collision cascade, followed by a summary of the various microstructures which can be formed after ion implantation into metals. This is compared with the variability of microstructures that can be achieved by rapid solidification processing. The microstructures are subsequently discussed in the light of the processes which, as the implantations proceed, take place during and immediately after formation of the individual collision cascades. These collision cascades define the volumes inside which individual ions are slowed down in the implanted targets. They are not only centres for vigorous agitation but also the sources for formation of excess concentrations of point defects, which will influence development of particular microstructures. A final section presents a selection of specific structures which have been observed in different alloy systems. (orig./GSCH)

  7. Development of a New Intravascular Low-Profile Device for Exclusion of Aortic Aneurysm: An Experimental Pilot Study

    International Nuclear Information System (INIS)

    Strecker, Ernst-Peter; Haberstroh, Joerg; Boos, Irene; Metz, Stephan; Langer, Mathias; Moliner, Manuel Maynar

    2004-01-01

    Purpose: To present a new intravascular device for the treatment of aorto-iliac aneurysms. Methods: This new device was tested in five dogs with abdominal aortic aneurysm created experimentally by overdilation of a balloon-expandable stent with a 16 or 18 mm wide PTA balloon catheter. The design of the device is based on a self-expanding aortic stent which consists of two stretchable circular frames filled with a textile Dacron mesh membrane that is suspended horizontally into the infrarenal abdominal aorta proximally to the aneurysm. The frames are part of a preshaped double helical structure that is introduced longitudinally through a catheter in a parallel fashion and forming the desired shape at the vessel site to be occluded. Two iliac stent-grafts are introduced in a low-profile status through the membrane sealing the aneurysm sac and holding the stent-grafts in place. After stent-graft expansion, a new bifurcation located more proximally than the natural one is created. The follow-up of the dogs was performed clinically and angiographically, and specimens were evaluated histomorphologically. Results: The membrane device can be introduced through a 9 Fr vascular sheath. Technical success was achieved in four of five dogs. Nine of ten stent-grafts could be fixed securely within the membrane, thus preventing dislocation. Aneurysms were excluded immediately, and blood flow to the external iliac arteries was restored by the stent-grafts. At 6-9 months follow-up of technically successful implanted devices, there were no endoleaks, no migration, no stenoses at contact sites between the implant material and vascular wall, and no stenosis or occlusion of the stent-grafts. At microscopic evaluation, the interspace between the membranes was filled with thrombotic material, thus ensuring exclusion of the aneurysm. Conclusion: This new device was found to be flexible, low profile and useful in excluding abdominal aortic aneurysm in the experimental setting

  8. El dispositivo: una grilla de análisis en la visibilización de las subjetividades

    Directory of Open Access Journals (Sweden)

    Jorge Eliécer Martínez Posada

    2013-01-01

    Full Text Available Este artículo es un análisis de las formas en que diversos autores presentan el concepto de dispositivo, de ahí que es un visibilizar algunos puntos de convergencia y aproximación a este concepto. La propuesta es comprender una forma de lectura y/o análisis de la realidad que permitirá pensar «el dispositivo» como elemento metodológico, reconociendo el lugar teórico de Michel Foucault en el mismo, para quien el dispositivo es la red que puede establecerse entre un conjunto heterogéneo de elementos que incluye discursos, instituciones, reglamentos, leyes, medidas administrativas, enunciados científicos, proposiciones filosóficas y morales; que tiene siempre una función estratégica concreta y se inscribe siempre en una relación de poder.

  9. Currently available methodologies for the processing of intravascular ultrasound and optical coherence tomography images.

    Science.gov (United States)

    Athanasiou, Lambros; Sakellarios, Antonis I; Bourantas, Christos V; Tsirka, Georgia; Siogkas, Panagiotis; Exarchos, Themis P; Naka, Katerina K; Michalis, Lampros K; Fotiadis, Dimitrios I

    2014-07-01

    Optical coherence tomography and intravascular ultrasound are the most widely used methodologies in clinical practice as they provide high resolution cross-sectional images that allow comprehensive visualization of the lumen and plaque morphology. Several methods have been developed in recent years to process the output of these imaging modalities, which allow fast, reliable and reproducible detection of the luminal borders and characterization of plaque composition. These methods have proven useful in the study of the atherosclerotic process as they have facilitated analysis of a vast amount of data. This review presents currently available intravascular ultrasound and optical coherence tomography processing methodologies for segmenting and characterizing the plaque area, highlighting their advantages and disadvantages, and discusses the future trends in intravascular imaging.

  10. RemoteBot: una aplicación que combina robots y dispositivos móviles

    OpenAIRE

    Queiruga, Claudia Alejandra; Banchoff Tzancoff, Claudia M.; López, Fernando

    2013-01-01

    RemoteBot es una aplicación clienteservidor que permite controlar los robots del proyecto "Programando con Robots y Software Libre" mediante dispositivos móviles Android. RemoteBot es una aplicación innovadora que combina robots con dispositivos móviles. RemoteBot es el resultado de la articulación del proyecto de I+D "Programando con Robots y Software Libre" con la cátedra “Laboratorio de Software” de 4to. año de las carreras Lic. en Informática y Lic. en Sistemas de la Facultad de Inf...

  11. Identificación de la fuente en vídeos de dispositivos móviles

    OpenAIRE

    Arenas González, David Manuel; Rosales Corripio, Jocelin; Sandoval Orozco, Ana Lucila; Romo Torres, Hiram Jafet; García Villalba, Luis Javier

    2014-01-01

    La realización de vídeos con dispositivos móviles se ha convertido en una actividad común dado su alto grado de utilización y el gran número de usuarios. Además, la portabilidad de este tipo de dispositivos hace que estén a mano de los usuarios gran cantidad de tiempo facilitando que se utilicen para generar vídeos en una gran diversidad de situaciones. Por tanto, estos vídeos pueden ser utilizados como evidencias en procesos judiciales. Todo lo anterior hace necesario contar con técnicas de ...

  12. Marketing en dispositivos m??viles, comportamiento del consumidor y estrategias de mercado = Mobile marketing, consumer behaviour and market strategies

    OpenAIRE

    Alonso de Linaje D??ez, Marta

    2015-01-01

    Desde su creaci??n en el a??o 1973, el m??vil y todo lo relacionado con el mismo ha sufrido un crecimiento imparable. Ha habido una gran evoluci??n tanto en los hardware de los dispositivos m??viles como en las prestaciones que estos ofrecen. El consumidor de contenido m??vil emplea cada vez m??s este dispositivo que le facilita el d??a a d??a tanto en el trabajo como en su vida cotidiana, produci??ndose un incremento de la dependencia de las personas hacia estos aparatos. Debido a esto, las ...

  13. Seguridad en smartphones: análisis de riesgos, de vulnerabilidades y auditorías de dispositivos

    OpenAIRE

    García Altarejos, Carlos

    2017-01-01

    El objetivo principal del trabajo es el desarrollo de una metodología de análisis forense, adaptada a dispositivos con sistema operativo Android. Se analiza el estado del arte de la seguridad en dispositivos móviles inteligentes, así como las amenazas más comunes. Se detalla la arquitectura de seguridad de Android y las vulnerabilidades con más impacto que le han afectado y se describen acciones preventivas y consideraciones para la mitigación de riesgos de seguridad. Se complementa el trabaj...

  14. Desenvolvimento de dispositivo de electroterapia para medicina física e reabilitação

    OpenAIRE

    Leitão, Cátia Sofia Jorge

    2010-01-01

    A electroterapia é uma das modalidades terapêuticas mais usadas em Medicina Física e Reabilitação. A presente dissertação assenta no desenvolvimento de um protótipo de dispositivo de aplicação de correntes eléctricas de baixa e média frequência. O objectivo principal é assim a recolha e especificação de requisitos técnicos e regulamentares para a concepção, desenvolvimento e prototipagem de equipamentos de electroterapia. A recolha de requisitos técnicos para desenvolver um dispositivo méd...

  15. Hypersensitivity reactions to metallic implants-diagnostic algorithm and suggested patch test series for clinical use

    DEFF Research Database (Denmark)

    Schalock, Peter C; Menné, Torkil; Johansen, Jeanne D

    2011-01-01

    algorithm to guide the selection of screening allergen series for patch testing is provided. At a minimum, an extended baseline screening series and metal screening is necessary. Static and dynamic orthopaedic implants, intravascular stent devices, implanted defibrillators and dental and gynaecological......Cutaneous and systemic hypersensitivity reactions to implanted metals are challenging to evaluate and treat. Although they are uncommon, they do exist, and require appropriate and complete evaluation. This review summarizes the evidence regarding evaluation tools, especially patch and lymphocyte...... transformation tests, for hypersensitivity reactions to implanted metal devices. Patch test evaluation is the gold standard for metal hypersensitivity, although the results may be subjective. Regarding pre-implant testing, those patients with a reported history of metal dermatitis should be evaluated by patch...

  16. Perioperative Intravascular Fluid Assessment and Monitoring: A Narrative Review of Established and Emerging Techniques

    Directory of Open Access Journals (Sweden)

    Sumit Singh

    2011-01-01

    Full Text Available Accurate assessments of intravascular fluid status are an essential part of perioperative care and necessary in the management of the hemodynamically unstable patient. Goal-directed fluid management can facilitate resuscitation of the hypovolemic patient, reduce the risk of fluid overload, reduce the risk of the injudicious use of vasopressors and inotropes, and improve clinical outcomes. In this paper, we discuss the strengths and limitations of a spectrum of noninvasive and invasive techniques for assessing and monitoring intravascular volume status and fluid responsiveness in the perioperative and critically ill patient.

  17. Monooxignase ensymic system of a liver of rats exposed to intravascular laser irradiation of blood

    International Nuclear Information System (INIS)

    Ibadova, G.A.

    1997-01-01

    Experimental study of the dynamic monooxidation of liver enzymic system was carried out on rats with experimental salmonellosis and the influence of the blood intravascular laser irradiation of blood on these enzymes was revealed. It was determined that by experimental salmonellosis oppression of the MOES activity of hepatocytes occurred. The blood intravascular irradiation by He-Ne laser promotes MOES oppression in rats suffered from salmonellosis. IVLIB as well as UV-laser show pronounced effect on the enzymes detoxication protection, mobilize their resistance to endogenic intoxication under the conditions of experimental salmonellosis. (author)

  18. Use of carbon dioxide as an intravascular contrast agent: A review of current literature

    OpenAIRE

    Ali, Fahad; Mangi, Muhammad Asif; Rehman, Hiba; Kaluski, Edo

    2017-01-01

    Use of X-ray contrast allows us to differentiate between two or more adjacent structures on radiographic studies. The X-ray contrast agent can be the one with increase X-ray absorption, like iodine and a barium X-ray contrast agent or the one with decrease X-ray absorption like air and carbon dioxide contrast agent. Each contrast agent possesses different risks and benefits in various ways. Carbon dioxide as an intravascular contrast agent can be used as an alternative intravascular contrast ...

  19. Leiomyosarcoma of the Uterus with Intravascular Tumor Extension and Pulmonary Tumor Embolism

    International Nuclear Information System (INIS)

    McDonald, Douglas K.; Kalva, Sanjeeva P.; Fan, C.-M.; Vasilyev, Aleksandr

    2007-01-01

    We report the case of a 48-year-old woman presenting with recurrent uterine leiomyosarcoma (LMS) associated with right iliac vein and inferior vena cava (IVC) invasion and left lower lobe pulmonary tumor embolus. Because the prognosis and treatment differ from that of thrombotic pulmonary emboli, the differentiating imaging characteristics of intravascular tumor embolism are reviewed. To our knowledge, only two other cases of intravenous uterine leiomyosarcomatosis have been described in the existing literature, and this is the first reported case of the entity with associated intravascular tumor embolism

  20. Intravascular brachytherapy in prevention of the secondary restenosis angioplasty transluminal coronaries

    International Nuclear Information System (INIS)

    Mejia, S.

    2001-01-01

    The radiotherapy coronary intravascular has demonstrated in a convincing way in clinical and experimental studies that produces a favorable decrease of the restenosis process. There is enough evidence to define this technique as the main current therapeutic option in the handling of the reestenosis intra stent. Accumulated experience exists of up to 3 years in patient's treaties with radiation gamma and multiple studies in several centers that demonstrate similar benefits with issuing beta. The present articulates it revises a series of radiotherapy systems and makes a setting a day on the employment of the brachytherapy intravascular in cardiologic patient

  1. Intravascular ultrasound evaluation of a pseudolesion created by stent placement in the right artery.

    Science.gov (United States)

    Zientek, D M; Rodgers, G P

    1999-10-01

    The creation of a pseudolesion after guidewire placement in tortuous arterial segments is a well recognized phenomenon. Intravascular ultrasound has been useful in assessing deployment of intracoronary stents and equivocal angiographic findings. We present a case in which a pseudolesion was not observed until after placement of an intracoronary stent. Intravascular ultrasound demonstrated no dissection or significant lesion; however, there was focal calcification just distal to the stent providing a substrate for the distorted vessel architecture. The lesion resolved with removal of the guidewire.

  2. Dispositivo Robótico Multifuncional para la Rehabilitación de las Extremidades Superiores

    Directory of Open Access Journals (Sweden)

    Aitziber Mancisidor

    2018-03-01

    Full Text Available En este trabajo se presenta un dispositivo de rehabilitación innovador por su flexibilidad y eficiencia denominado Universal Haptic Pantograph (UHP. Este robot, gracias a su estructura multi-configurable permite la rehabilitación del miembro superior con un único dispositivo. Además, se ha diseñado con la habilidad de realizar diferentes tareas asistivas y resistivas, pudiendo así adaptarse al estado de recuperación del paciente. Finalmente, el software Telereha genera un entorno de realidad virtual que facilita la ejecución del ejercicio y aumenta la motivación del paciente. El sistema de control del robot se ha implementado entiempo real con el fin de garantizar la correcta ejecución de las tareas de rehabilitación. Usando este sistema, se han realizado diferentes ensayos experimentales.  Los resultados demuestran que el robot de rehabilitación UHP funciona  correctamente  con diferentes tareas de rehabilitación, realizando movimientos suaves y seguros que garantizan la seguridad del usuario.

  3. Tratamiento endovascular de una fuga paraprotésica mitral con dispositivo Amplatzer®

    Directory of Open Access Journals (Sweden)

    Alberto Sciegata

    2012-10-01

    Full Text Available El leak o fuga paraprotésica mitral se presenta entre el 5 y el 17% de los pacientes tratados con cirugía de reemplazo valvular. En general, los defectos son únicos, la mayoría se encuentran localizados en la región postero-medial del anillo valvular y solo la tercera parte produce reflujo de grado grave. El cierre percutáneo por vía endovascular es una alternativa terapéutica válida en pacientes con elevado riesgo para re-operación. La estrategia de abordaje depende de la localización, tamaño, morfología y relaciones adyacentes del o los defectos. El procedimiento debe ser realizado por profesionales con experiencia en el tratamiento de cardiopatías estructurales y en el manejo de estos dispositivos de cierre, y se considera imprescindible la utilización de un ecocardiograma transesofágico tridimensional. Se presenta el caso de un paciente con una fuga paraprotésica valvular mitral que fue cerrada con un dispositivo Amplatzer ® introducido en forma percutánea desde la vena femoral.

  4. El dispositivo de subjetivación escolar: el poder, el saber, el deseo

    Directory of Open Access Journals (Sweden)

    Mónica Zuleta P

    1995-04-01

    Full Text Available Este ensayo propone una mirada que busca abrir nuevos caminos para el desarrollode investigaciones sobre violencia. Esta mirada está inscrita dentro de un marco orientado por opciones teóricas en las que se describe la manera como los sujetos y los objetos se dan forma en el juego de la relación de líneas de fuerzas referidas al poder, al saber y al deseo, líneas que generan dispositivos de subjetivación. Desde esta perspectiva, no existe un sujeto que ya constituído, voluntariamente pretenda orientar su acción para el logro de determinados fines del objeto, sino, por el contrario, son las fuerzas las que conforman tanto a los sujetos como a los objetos, al originar códigos variables, que dependen de la dirección que imprima la interacción de las fuerzas. La escuela, como espacio en el que confluyen todas las fuerzas en su movimiento constante, constituye subjetividades, atrapadas en dispositivos de poder con propósitos diferentes; pero también posibilita fugas a los códigos. Es en este espacio móvil del código y de la fuga, donde proponemos situar la disposición para la violencia.

  5. EL DISPOSITIVO DE SUBJETIVACION ESCOLAR: EL PODER, EL SABER, EL DESEO

    Directory of Open Access Journals (Sweden)

    Mónica Zuleta P.

    1995-01-01

    Full Text Available Este ensayo propone una mirada que busca abrir nuevos caminos para el desarrollo de investigaciones sobre violencia. Esta mirada está inscrita dentro de un marco orientado por opciones teóricas en las que se describe la manera como los sujetos y los objetos se dan forma en el juego de la relación de líneas de fuerzas referidas al poder, al saber y al deseo, líneas que generan dispositivos de subjetivación. Desde esta perspectiva, no existe un sujeto que ya constituído, voluntariamente pretenda orientar su acción para el logro de determinados fines del objeto, sino, por el contrario, son las fuerzas las que conforman tanto a los sujetos como a los objetos, al originar códigos variables, que dependen de la dirección que imprima la interacción de las fuerzas. La escuela, como espacio en el que confluyen todas las fuerzas en su movimiento constante, constituye subjetividades, atrapadas en dispositivos de poder con propósitos diferentes; pero también posibilita fugas a los códigos. Es en este espacio móvil del código y de la fuga, donde proponemos situar la disposición para la violencia.

  6. Condiciones térmicas de un dispositivo electrónico en caso de incendio.

    Directory of Open Access Journals (Sweden)

    Bruno Chinè

    2008-05-01

    Full Text Available En este trabajo se presentan los resultados de una simulación numérica llevada a cabo para analizar las condiciones térmicas a la cual un sistema electrónico, usado para radiocomunicaciones en túneles, podría estar sujeto en caso de incendio.El sistema se compone de un dispositivo electrónico contenido en una caja metálica de acero inoxidable 316, un cable coaxial interno y un cable coaxial externo de cobre. Sobre el sistema que se alberga en una cámara de polímero concreto con una ventana en mica, había sidorealizada una prueba al fuego con registro experimental de los valores de temperaturaen diferentes puntos del sistema. El trabajo de simulación numérica se desarrolla usando el software comercial Comsol Multiphisics. El propósito es estudiar los dos mecanismos de transferencia de calor que controlan la temperatura del dispositivo, en particular la conduccióntérmica a través de la pared de polímero concreto y la ventana en mica, más la transmisión de calor a lo largo del cable coaxial externo. Los resultados numéricos confirman los perfiles de temperatura de la prueba experimental y permiten analizar el comportamiento de los materiales bajo otras condiciones térmicas.

  7. Dispositivos para generación de discurso y fundamentos conceptuales del trabajo infantil

    Directory of Open Access Journals (Sweden)

    Juan Manuel Estrada-Jiménez

    2015-03-01

    Full Text Available En este avance de investigación proponemos una metodología para el trabajo con niños y niñas, basada en dos dispositivos para la generación de discurso por medio de la actividad lúdica: un dispositivo destinado a la identificación de las dinámicas relacionales en el contexto de la familia, y otro orientado al reconocimiento de las formas en que se reproducen estas dinámicas en el entorno escolar. Igualmente presentamos las categorías analíticas que han servido para definir la situación de la infancia trabajadora, a partir de la identificación de temas centrales en el discurso de revistas especializadas sobre el tema, desplegando estas categorías como los fundamentos hermenéuticos que permitirán identificar a los niños y niñas como actores sociales productivos, y como ciudadanos y ciudadanas con derechos y deberes que demandan ser respetados.

  8. Normatividad para las frecuencias ISM orientada hacia aplicaciones de dispositivos Xbee-802.15.4-Pro

    Directory of Open Access Journals (Sweden)

    Gustavo Emilio Echeverry Vásquez

    2014-07-01

    Full Text Available Los dispositivos de comunicación inalámbricos existentes pueden llegar a generar pérdidas en la información transmitida, inherentes al tratamiento de los datos a transmitir. La tecnología WLAN (Red de Área Local Inalámbrica está ligada a las restricciones propias de los dispositivos, teniendo en cuenta parámetros como: ancho de banda, potencia de radiación y el alcance de los mismos. Es por esto que en la actualidad se ha avanzado en el desarrollo de sistemas que permiten trabajar con mayor velocidad y procesamiento de información, facilitando así la interacción con el usuario. Los resultados mostrados en este artículo demuestran que es posible transmitir señales de tipo biomédico, sean electrocardiográficas (ECG, respiración o presión sanguínea (BP, de forma inalámbrica bajo una frecuencia de 2,4GHz, lo anterior sujeto también a la regulación existente en Colombia, que conoceremos en este documento, y que permite realizar actividades de tipo industrial, científica y médica (ISM.

  9. Distribution of nickel after modified nitinol stent implantation in animals

    Science.gov (United States)

    Chepeleva, E.; Sergeevichev, D.; Lotkov, A.; Kashin, O.; Korobeynikov, A.; Kozyr, K.; Baystrukov, V.; Zubarev, D.; Kretov, E.; Pokushalov, E.

    2017-09-01

    Intravascular stenting of arteries in atherosclerotic lesions is one of the most frequently performed procedures in cardiovascular surgery today. Most stents are made of various stainless-steel alloys and other metals (such as nitinol). Nitinol is a biocompatible, superplastic and corrosion resistant material with an important feature of shape memory. However, the composition of this alloy includes nickel, which shows toxicity to the kidneys, liver, lungs, heart and other organs when it accumulates in the organism. In this research we investigated the nickel content in serum, urine and hair of the laboratory animals after implantation of nitinol stents treated with plasma ionic surface modification by silicon.

  10. Carmustine Implant

    Science.gov (United States)

    ... works by slowing or stopping the growth of cancer cells in your body. ... are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while receiving carmustine implant, call your doctor. Carmustine may harm the fetus.

  11. Cochlear Implants

    Science.gov (United States)

    ... NIDCD A cochlear implant is a small, complex electronic device that can help to provide a sense ... Hearing Aids Retinitis Pigmentosa - National Eye Institute Telecommunications Relay Services Usher Syndrome Your Baby's Hearing Screening News ...

  12. Use of an Intravascular Fluorescent Continuous Glucose Sensor in ICU Patients

    NARCIS (Netherlands)

    Strasma, Paul J.; Finfer, Simon; Flower, Oliver; Hipszer, Brian; Kosiborod, Mikhail; Macken, Lewis; Sechterberger, Marjolein; van der Voort, Peter H. J.; DeVries, J. Hans; Joseph, Jeffrey I.

    2015-01-01

    Hyperglycemia and hypoglycemia are associated with adverse clinical outcomes in intensive care patients. In product development studies at 4 ICUs, the safety and performance of an intravascular continuous glucose monitoring (IV-CGM) system was evaluated in 70 postsurgical patients. The GluCath

  13. Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? A prospective observational study

    DEFF Research Database (Denmark)

    Johansson, Per Ingemar; Sorensen, Anne Marie; Perner, Anders

    2011-01-01

    ABSTRACT: INTRODUCTION: It is debated whether the early trauma induced coagulopathy (TIC) in severely injured patients reflects disseminated intravascular coagulation (DIC) with a fibrinolytic phenotype, acute coagulopathy of trauma shock (ACoTS) or yet other entities. This study investigated the...

  14. Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation

    NARCIS (Netherlands)

    Bakhtiari, Kamran; Meijers, Joost C. M.; de Jonge, Evert; Levi, Marcel

    2004-01-01

    Objectives: A diagnosis of disseminated intravascular coagulation (DIC) is hampered by the lack of an accurate diagnostic test. Based on the retrospective analysis of studies in patients with DIC, a scoring system (0-8 points) using simple and readily available routine laboratory tests has been

  15. Disseminated intravascular coagulation as an unusual presentation of an Epstein-Barr virus infection

    NARCIS (Netherlands)

    van Steijn, JHM; van Tol, KM; van Essen, LH; Gans, ROB

    2000-01-01

    Epstein-Barr viral (EBV)-infection usually presents as fever, sore throat, fatigue, lymphadenopathy and atypical lymphocytosis. We describe a patient with disseminated intravascular coagulation as the presenting symptom caused by a primary EBV infection. (C) 2000 Elsevier Science B.V. All rights

  16. Implantation, recoil implantation, and sputtering

    International Nuclear Information System (INIS)

    Kelly, R.

    1984-01-01

    The implantation and sputtering mechanisms which are relevant to ion bombardment of surfaces are described. These are: collision, thermal, electronic and photon-induced sputtering. 135 refs.; 36 figs.; 9 tabs

  17. Análisis de discurso y dispositivo en una 'political ecology' de extractivismo aurífero (Colombia)

    OpenAIRE

    Pignolet, Thierry

    2017-01-01

    Este trabajo de seminario doctoral de profundización en ciencias sociales expone la teoría y la metodología movilizadas en la investigación del doctorando -a saber, el análisis de discurso y dispositivo (de Siegfried JÄGER y Florentine MAIER) en una 'political ecology' de extractivismo minero (Colombia).

  18. Dispositivo didáctico para el aprendizaje significativo de la Química

    Directory of Open Access Journals (Sweden)

    Antonio Alberto García García

    2015-10-01

    Full Text Available Se presenta un estudio cuasiexperimental realizado con estudiantes de décimo grado de la Institución Educativa Distrital (IED San José de la ciudad de Barranquilla. Para desarrollarlo, se constituyó un grupo experimental y un grupo control, con prueba de equivalencia, con la intención de implementar un dispositivo de intervención denominado Guías integradoras, que fueron diseñadas bajo los principios del aprendizaje significativo propuesto por Ausubel, Novak & Hanessian (1983 y las destrezas de pensamiento de Villarini (1991. Al mismo tiempo, se determinó la efectividad generada por dicho dispositivo en la optimización de los procesos de enseñanza y aprendizaje de contenidos asociados a la Química. Los resultados estadísticos obtenidos luego de la aplicación de la “t” de Student a la postprueba administrada indican diferencias significativas a favor del grupo experimental estimulado con el dispositivo, en detrimento del grupo control sometido a enseñanza tradicional. AbstractA quasi-experimental study conducted with tenth grade of Institución EducativaDistrital (IED San José from Barranquilla. To develop it, it was an experimental group and a control group with proof of equivalence, in order to implement an intervention device called Inclusive guides, that were designed under the principles of meaningful learning proposed by Ausubel, Novak & Hanessian (1983 and Villarini’s intelect skills. At the same time, the effectiveness generated by such a device in the optimization of the processes of teaching and learning of content associated with the Chemistry was determined. The statistical results obtained after the application of the “t” of Student to the managed post-test shows huge differences in favor of the experimental group stimulated with the device, to the detriment of the group control subjected to traditional teaching.

  19. Empréstimo de dispositivos de leitura em bibliotecas: análise de experiências

    Directory of Open Access Journals (Sweden)

    Liliana Giusti Serra

    Full Text Available RESUMO Os livros digitais estão aumentando sua presença nos acervos das bibliotecas. Contudo, sua inclusão nas rotinas bibliotecárias causa dúvidas, desde as possibilidades de aquisição, às formas de acesso e utilização pelos usuários. O objetivo deste artigo é alertar as bibliotecas brasileiras para o processo de implantação dos livros digitais por meio de empréstimo de dispositivos de leitura. Metodologicamente, trata-se de estudo descritivo exploratório, que por meio de levantamento bibliográfico elabora revisão de literatura sobre as experiências que identificam aspectos positivos e negativos na adoção e uso de dispositivos de leitura como forma de acesso dos conteúdos digitais. São analisadas as experiências da River Forest Public Library e Mentor Public Library (MPL. Na discussão dos resultados, elenca-se recomendações que devem ser consideradas pela biblioteca ao optar pela implantação de serviço de empréstimo de dispositivos de leitura. As considerações finais destacam que a inclusão de dispositivos de leitura em bibliotecas e sua circulação são iniciativas interessantes, mas não podem ser consideradas políticas para acesso de livros digitais pelos usuários. Entretanto, pode ser adotada por instituições que ainda não estão familiarizadas com os dispositivos e com a experiência da leitura de livros digitais.

  20. Vejiga perforada por dispositivo intrauterino: Presentación de 1 caso

    Directory of Open Access Journals (Sweden)

    Luis Gómez Pérez

    2001-03-01

    Full Text Available Se presenta el caso de una paciente femenina de 32 años de edad que consulta al ginecólogo por presentar dolor mantenido de mediana intensidad en hipogastrio y crisis de sepsis urinaria repetida. Se comprobó la presencia de un cuerpo extraño (dispositivo intrauterino en la vejiga, mediante la realización de endoscopia y por esta vía se logró extraer. Actualmente la paciente está asintomáticaA 32 year-old female patient who visits the gynecologist due to a mantained pain of moderate intensity in the hypogastrium and repeated crises of urinary sepsis is presented. The presence of a foreign body (intrauterine device in the urinary bladder is proved by endoscopy, which is also used to extract it. At present, the patient is asymptomatic

  1. Proposta de um modelo para redes de dispositivos telemáticos

    OpenAIRE

    Francisco José Monaco

    2002-01-01

    Avanços técnicos na integração dos sistemas de comunicação e computação têm revelado interesse científico as potencialidades das redes de dispositivos telemáticos - nas quais integram equipamentos dotados de capacidade de transmissão e processamento de informação - em áreas que cobrem desde o ensino à distância, até telemedicina, automação remota e tele-instrumentação científica. Especialmente em virtude do reconhecimento das destacadas facilidades da Internet, dentre as aplicações mais visad...

  2. Desarrollo de un SIG para dispositivos móviles utilizando gvSIG Mobile

    OpenAIRE

    Pérez Álvarez, Francisco

    2012-01-01

    Este proyecto se inicia con la introducción al mundo de los SIG basados en software de código abierto, como es el caso del gvSIG Mobile y gvSIG Desktop. Basándonos en estos dos programas, hemos creado una aplicación SIG para dispositivos móviles (PDA’s y smartphones) gracias a la cual, será posible actualizar cartografía en tiempo real directamente en campo. Para introducirse de pleno en el tema del proyecto, se realizó un análisis detallado sobre las necesidades que podrían existir a l...

  3. Dispositivos reductores de velocidad vehicular: Hacia el desarrollo de nuevos diseños

    OpenAIRE

    Fredy Alberto Guío Burgo

    2010-01-01

    Expone  el  resultado  de  varias  pruebas  de  campo realizadas a dos dispositivos reductores de velocidad vehicular,  basados  en  la  generación  de  ilusiones  o efectos ópticos, que inducen al conductor a disminuir la velocidad de marcha; se evaluó el desempeño de los diseños mediante estudios de velocidad de punto del  tipo  antes  y  después, mediante  pruebas  dehipótesis  estadísticas  que  demostraron  que  la reducción obtenida fue significativa para la mayoría de  los  usuarios, e...

  4. Dispositivo de Potterheads: Organização Pautada na Ordem do Cânone

    Directory of Open Access Journals (Sweden)

    Flávia Zimmerle da Nóbrega Costa

    2017-07-01

    Full Text Available Os fãs da saga Harry Potter, conhecidos como potterheads, pertencem a uma geração que cresceu em um contexto denominado cultura da convergência. Organizam-se a partir de um produto midiático em um espaço social denominado fandom, por meio de um processo organizativo informal. Embasados no pensamento foucaultiano e na teoria organizacional, assumimos que processos organizativos podem ser analisados como um tipo de dispositivo e que este se estabelece por práticas. Com base nisso, desenvolvemos a seguinte questão investigativa: como as práticas dos potterheads evidenciam seu processo organizativo? A pesquisa se caracteriza como uma Análise de Discursos Foucaultiana, com base em práticas de potterheads observadas em mídias sociais. Como resultado, identificamos que o cânone deste universo literário e cinematográfico funciona como um corpo de saberes ordenado, cuja função disciplinar possibilita a organização de seus fãs, que se dá numa dinâmica de aderência e resistência ao mesmo. O estudo revela como um processo organizativo singular (vida organizada dos potterheads, vinculado a um cenário econômico de crescente importância (indústria do entretenimento, ilustra como um dispositivo opera na produção de espaços sociais e subjetividades, em meio a uma economia afetiva operada como uma tecnologia biopolítica.

  5. Dispositivos pedagógicos y trayectorias escolares en contexto de desigualdad social

    Directory of Open Access Journals (Sweden)

    Eduardo Daniel Langer

    2014-06-01

    Full Text Available Transcurridas las reformas educativas del 90 y del 2000, nuestra preocupación se centró en las lógicas que a partir de allí ha ido asumiendo la escolaridad. El problema que abordó este proyecto, giró en orden a describir qué características y qué sentidos están asumiendo los dispositivos pedagógicos hoy. El concepto de dispositivo pedagógico nos permite preguntarnos por las formas que asume la institución educación, la regulación de la vida escolar, los sentidos que se construyen en el cotidiano escolar desde la perspectiva de los estudiantes. En este sentido, importa describir la escolaridad en su presente atendiendo las nuevas formas de desigualdad social y el crecimiento de la polarización social. Nos propusimos avanzar sobre los sentidos que los propios estudiantes le otorgan a su tránsito por la escuela: ¿Cómo piensan a la escuela? ¿Para qué creen que sirve la escuela? ¿Qué les gusta de la escuela? ¿Qué valoraciones hacen respecto de las normas en el aula y en la escuela? ¿Qué no les gusta de la escuela? ¿Cómo piensan el mundo en el futuro? ¿Cuáles son sus intereses dentro y fuera de la escuela? Estos son algunos de los interrogantes a partir de los cuales se intentó reconstruir los discursos de la población escolar en la actualidad, los que-atravesados por algunos condicionamientos objetivos-nos permitieron avanzar en la reconstrucción de algunos de los sentidos posibles que la población estudiada le otorga a su trayectoria escolar, en la escuela del siglo XXI.

  6. Hip Implant Systems

    Science.gov (United States)

    ... Implants and Prosthetics Metal-on-Metal Hip Implants Hip Implants Share Tweet Linkedin Pin it More sharing options Linkedin Pin it Email Print Hip implants are medical devices intended to restore mobility ...

  7. Breast reconstruction - implants

    Science.gov (United States)

    Breast implants surgery; Mastectomy - breast reconstruction with implants; Breast cancer - breast reconstruction with implants ... harder to find a tumor if your breast cancer comes back. Getting breast implants does not take as long as breast reconstruction ...

  8. Mejora en el interfaz de un dispositivo móvil para personas con discapacidad visual mediante el diseño de iconos hápticos

    OpenAIRE

    Galdón Conejo, Pedro María

    2014-01-01

    La mayoría de los interfaces de los actuales dispositivos móviles se basan en la visión para comunicar la información al usuario. Sin embargo, debido a que el usuario no se encuentra continuamente mirando la pantalla del dispositivo, y al reducido tamaño de las mismas, la interacción visual con dichos dispositivos suele complementarse con el uso de sonidos. No obstante, si el entorno es ruidoso el uso de sonidos resulta ineficaz, como también resulta ineficaz su uso si se requiere estar en si...

  9. Aplicación de los Dispositivos Móviles para el control y análisis de la cartografía catastral.

    OpenAIRE

    CLERIGUES GARCIA, ENRIQUE

    2015-01-01

    [ES] Utilización de dispositivos móviles para control de parcelas catastrales, en la que el usuario, previamente registrado e identificado, puede mediante su dispositivo obtener las coordenadas de los vértices que definen la figura de un bancal/huerto situándose en cada uno de los vértices. Posteriormente, una vez realizada la toma de datos, el usuario envía estos datos desde su dispositivo a un geoportal web, el cual también crearemos nosotros. En dicho geoportal, el usuario previamente regi...

  10. Newly Developed Biocompatible Material: Dispersible Titanium-Doped Hydroxyapatite Nanoparticles Suitable for Antibacterial Coating on Intravascular Catheters.

    Science.gov (United States)

    Furuzono, Tsutomu; Okazaki, Masatoshi; Azuma, Yoshinao; Iwasaki, Mitsunobu; Kogai, Yasumichi; Sawa, Yoshiki

    2017-01-01

    Thirteen patients with chlorhexidine-silver sulfadiazine-impregnated catheters have experienced serious anaphylactic shock in Japan. These adverse reactions highlight the lack of commercially available catheters impregnated with strong antibacterial chemical agents. A system should be developed that can control both biocompatibility and antibacterial activity. Hydroxyapatite (HAp) is biocompatible with bone and skin tissues. To provide antibacterial activity by using an external physical stimulus, titanium (Ti) ions were doped into the HAp structure. Highly dispersible, Ti-doped HAp (Ti-HAp) nanoparticles suitable as a coating material were developed. In 3 kinds of Ti-HAp [Ti/(Ca + Ti) = 0.05, 0.1, 0.2], the Ti content in the HAp was approximately 70% of that used in the Ti-HAp preparation, as determined by inductively coupled plasma atomic emission spectroscopy (ICP-AES). ICP-AES and X-ray diffraction showed Ti ions were well substituted into the HAp lattice. The nanoparticles were almost uniformly coated on a polyethylene (PE) sheet in a near-monolayer with a surface coverage ratio >95%. The antibacterial activity of the Ti-HAp nanoparticles containing 7.3% Ti ions and coating the sheet was evaluated by calculating the survival ratio of Pseudomonas aeruginosa on the coated sheet after ultraviolet (UV) irradiation. The Ti-HAp-coated sheet showed a 50% decrease in the number of P. aeruginosa compared with that on an uncoated control PE sheet after UV irradiation for 30 s. Key Messages: A system of biocompatibility and antibacterial activity with an on/off switch controlled by external UV stimulation was developed. The system is expected to be applicable in long-term implanted intravascular catheters. © 2017 S. Karger AG, Basel.

  11. A new method to measure necrotic core and calcium content in coronary plaques using intravascular ultrasound radiofrequency-based analysis

    NARCIS (Netherlands)

    E.S. Shin (Eun-Seok); H.M. Garcia-Garcia (Hector); P.W.J.C. Serruys (Patrick)

    2010-01-01

    textabstractAlthough previous intravascular ultrasound (IVUS) radiofrequency-based analysis data showed acceptable reproducibility for plaque composition, measurements are not easily obtained, particularly that of lumen contour, because of the limited IVUS resolution. The purpose of this study was

  12. Una apuesta analítica del funcionamiento del dispositivo psi pericial en el campo penal Uma aposta analitica do funcionamento do dispositivo psi pericial inserido no campo penal An analysis of the psy expert assemblage in the penal field

    Directory of Open Access Journals (Sweden)

    Laura López Gallego

    2010-08-01

    Full Text Available La aproximación al dispositivo psi pericial inserto en el campo penal aquí efectuada, traza un itinerario de análisis que aborda el funcionamiento de dicho dispositivo, poniendo especial énfasis en las imbricadas relaciones entre los saberes jurídicos y lo psi. Para efectuar dicho análisis, se utilizan documentos específicos producidos por los peritos psi en el marco del Poder Judicial del Uruguay. Se entiende a las prácticas psi como el efecto de ciertas confluencias históricas relacionadas con el examen, con las estrategias de objetividad, con la traducción de categorías psi en categorías jurídicas y con la incorporación de la lógica de individualización como eje del dispositivo psi pericial. La pregunta que guía el análisis versa sobre lo que posibilita la incorporación del dispositivo psi pericial en el campo penal.A aproximação ao dispositivo psi pericial inserido no campo penal aqui realizada traça um itinerário de análise que aborda o funcionamento do dispositivo, enfatizando as relações imbricadas entre os saberes jurídicos e psi. Para realizar a análise, utilizam-se documentos específicos produzidos por peritos psi no marco do Poder Judicial do Uruguai. Entendem-se as práticas psi como efeito de certas confluências históricas relacionadas ao exame, às estratégias de objetividade, à tradução de categorias psi em categorias jurídicas e à incorporação da lógica da individualização como um ponto central do dispositivo psi pericial. A pergunta que orienta a análise é o que possibilita a incorporação do dispositivo psi pericial no campo penal.The approach made here about the "expert psy assemblage" inserted into the criminal field draws a path of analysis that considers the operation of this assemblage, highlighting the intertwined relationships between the legal and psychological knowledge. To undertake such analysis, specific documents produced by the psy experts, working under the Judiciary

  13. P-shaped Coiled Stator Ultrasound Motor for Rotating Intravascular Surgery Device

    Directory of Open Access Journals (Sweden)

    Toshinobu ABE

    2015-01-01

    Full Text Available The primary focus of this paper is the development of an ultra-miniature ultrasound motor for use in the human blood vessel. Since the size of the drive source for rotating the atherectomy device and intravascular ultrasonography system are large currently in practical use, it is installed outside the body, and the rotational power for the atherectomy device and intravascular ultrasonography system are transmitted through the long tortuous blood vessel. Such systems suffer from the problem that the rotation becomes non-uniform, and the problem that the available time is limited. We have therefore developed a P-shaped coiled stator ultrasound motor as a miniature ultrasound motor for rotating the ultrasound sensor for use in blood vessels in order to solve these problems. In this paper, we describe measurement of the torque, revolution speed, output power, efficiency, and particle motion on acoustic waveguide of the P-shaped coiled stator ultrasound motor.

  14. Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest

    DEFF Research Database (Denmark)

    Glover, Guy W; Thomas, Richard M; Vamvakas, George

    2016-01-01

    , maintenance and rewarming phases in addition to adverse events. All-cause mortality, as well as a composite of poor neurological function or death, as evaluated by the Cerebral Performance Category and modified Rankin scale were analysed. RESULTS: For patients managed at 33 °C there was no difference between......BACKGROUND: Targeted temperature management is recommended after out-of-hospital cardiac arrest and may be achieved using a variety of cooling devices. This study was conducted to explore the performance and outcomes for intravascular versus surface devices for targeted temperature management after...... out-of-hospital cardiac arrest. METHOD: A retrospective analysis of data from the Targeted Temperature Management trial. N = 934. A total of 240 patients (26%) managed with intravascular versus 694 (74%) with surface devices. Devices were assessed for speed and precision during the induction...

  15. Transbiliary intravascular ultrasound-guided diagnostic biopsy of an inaccessible pancreatic head mass

    Directory of Open Access Journals (Sweden)

    Jeffrey Forris Beecham Chick, MD, MPH, DABR

    2017-06-01

    Full Text Available Percutaneous image-guided biopsies of pancreatic malignancies may prove challenging and nondiagnostic due to a variety of anatomic considerations. For patients with complex post-surgical anatomy, such as a Roux-en-Y gastric bypass, diagnosis via endoscopic ultrasound with fine-needle aspiration may not be possible because of an inability to reach the proximal duodenum. This report describes the first diagnostic case of transbiliary intravascular ultrasound-guided biopsy of a pancreatic head mass in a patient with prior Roux-en-Y gastric bypass for which a diagnosis could not be achieved via percutaneous and endoscopic approaches. Transbiliary intravascular ultrasound-guided biopsy resulted in a diagnosis of pancreatic adenocarcinoma, allowing the initiation of chemotherapy.

  16. Intravascular Papillary Endothelial Hyperplasia Associated with Venous Pool Arising in the Lower Lip: A Case Report

    Directory of Open Access Journals (Sweden)

    Hisanobu Yonezawa

    2009-01-01

    Full Text Available Intravascular papillary endothelial hyperplasia is a benign nonneoplastic vascular lesion that consists of endothelial cells with abundant vascular tissue with papillary proliferation. An adult female had a painless growing dark red nodule on the left side of the lower lip and often touched and gnawed at it for more than 4 years. The lesion was a tender, smooth mass approximately 1 cm in diameter without discoloration reaction. Magnetic resonance imaging of the lesion showed specific findings. She was diagnosed clinically as having mimicked hemangioma, and the lesion was totally excised under local anesthesia. Histopathological examination revealed that papillary proliferated endothelial cells with venous pool, and the lesion was diagnosed as intravascular papillary endothelial hyperplasia associated with venous pool. There has been no recurrence for more than 1 year. Despite the benign nature of this lesion, it could have been mistaken for a malignant tumor because of its clinical course and radiologic findings.

  17. Effect of catecholamines and insulin on plasma volume and intravascular mass of albumin in man

    DEFF Research Database (Denmark)

    Hilsted, J; Christensen, N J; Larsen, S

    1989-01-01

    1. The effect of intravenous catecholamine infusions and of intravenous insulin on plasma volume and intravascular mass of albumin was investigated in healthy males. 2. Physiological doses of adrenaline (0.5 microgram/min and 3 microgram/min) increased peripheral venous packed cell volume...... significantly; intravenous noradrenaline at 0.5 microgram/min had no effect on packed cell volume, whereas packed cell volume increased significantly at 3 micrograms of noradrenaline/min. No significant change in packed cell volume was found during saline infusion. 3. During adrenaline infusion at 6 micrograms...... in packed cell volume, plasma volume, intravascular mass of albumin and transcapillary escape rate of albumin during hypoglycaemia may be explained by the combined actions of adrenaline and insulin....

  18. Location of facts devices from a dynamic perspective; Ubicacion de dispositivos FACTS desde una perspectiva dinamica

    Energy Technology Data Exchange (ETDEWEB)

    Coronado Gallegos, Ixtlahuatl

    2001-09-15

    In this work techniques for the location of FACTS devices (Flexible Systems of AC Transmission) in a multi-machine power system in order to improve the electromechanical transient behavior is presented. In the first part, a brief introduction is presented about the FACTS devices, in which are mentioned some of the main characteristics, classification and advantages that their utilization represents. In the next part, the formulation of the matrix of state in the context of machine-infinite bar considering the possibility of including a power system stabilizer is developed. Later the formulation is extended to a multi-machine system. Additionally the form of including a series capacitor controlled by thyristors (TCSC) as well as a unified controller of power flows (UPFC) is analyzed. An analysis of the UPFC is carried out in conditions of stationary and dynamic state in a system machine-infinite bar in order to know its operating characteristics and its capacity for dampening power oscillations through its entrances of control when using local signals. In the last part of the work a methodology is proposed to attack the problem of the location of FACTS devices, which is based in the technique of response to the system frequency. In order to validate this proposal some cases of study are used and the results obtained with the ones provided by other techniques are compared. Also some auxiliary means are proposed for obtaining the feasible locations utilizing other mathematical tools such as the singular values and the sensitivities. Finally, simulations in the time are carried out to corroborate the results obtained. [Spanish] En este trabajo se presentan tecnicas para la localizacion de dispositivos FACTS (Sistemas Flexibles de Transmision de C.A) en un sistema de potencia multimaquinas a fin de mejorar el comportamiento transitorio electromecanico. En la primera parte se presenta una breve introduccion acerca de los dispositivos FACTS, en la cual se mencionan

  19. MRI evaluation and follow-up of bone necrosis after meningococcal infection and disseminated intravascular coagulation

    International Nuclear Information System (INIS)

    Damry, N.; Schurmans, T.; Perlmutter, N.

    1993-01-01

    Disseminated intravascular coagulation (DIC) is a serious complication of meningococcal septicaemia. It often results in infarction of various tissues namely the skin, adrenal glands, kidneys, brain and, much less commonly, bones. We describe a patient who presented bone lesions after meningococcal septicaemia. In addition to plain radiography and scintigraphy the lesions were evaluated with MRI and have proved to be extensive and still progressive, approxximately 18 months after the onset of the disease. (orig.)

  20. Novel Double-Needle System That Can Prevent Intravascular Injection of Any Filler

    Directory of Open Access Journals (Sweden)

    Hsiang Huang, MD

    2017-09-01

    Full Text Available Summary:. A new type of needle system combines 2 parts, an inner needle and an outer needle. The inner needle is used for filler injection and the outer needle acts as a guiding needle that can observe blood reflow when inserting into the vessel lumen during injection process. This new needle system can be used for all kinds of filler, providing real time monitoring for physician and preventing intravascular injection of any filler.

  1. Distribution of [35S] taurine in mouse retina after intravitreal and intravascular injection

    International Nuclear Information System (INIS)

    Pourcho, R.G.

    1977-01-01

    The distribution of [ 35 S] taurine in mouse retinae was studied by autoradiographic techniques after either intravitreal or intravascular injection. The route of injection did not affect the final localization. The major sites of label accumulation were the outer nuclear layer, the inner nuclear layer, and Mueller cell processes adjacent to the vitreal surface. The distribution was consistent with the interpretation that taurine was localized within two cellular compartments of mouse retina, photoreceptor cells and Mueller cells. (author)

  2. Association of insulin resistance and coronary artery remodeling: an intravascular ultrasound study

    OpenAIRE

    Kim, Sang-Hoon; Moon, Jae-Youn; Lim, Yeong Min; Kim, Kyung Ho; Yang, Woo-In; Sung, Jung-Hoon; Yoo, Seung Min; Kim, In Jai; Lim, Sang-Wook; Cha, Dong-Hun; Cho, Seung-Yun

    2015-01-01

    Background There are few studies that investigated the correlation between insulin resistance (IR) and the coronary artery remodeling. The aim of the study is to investigate the association of IR measured by homeostasis model assessment of insulin resistance (HOMA-IR) and coronary artery remodeling evaluated by intravascular ultrasound (IVUS). Methods A total of 298 consecutive patients who received percutaneous coronary interventions under IVUS guidance were retrospectively enrolled. The val...

  3. Control de un manipulador antropomórfico por medio de un dispositivo de inmersión

    Directory of Open Access Journals (Sweden)

    Ricardo A. Castillo

    2004-01-01

    Full Text Available Este trabajo consta de 3 etapas: a Construcción: dispositivo de inmersión, b Desarrollo: software de simulación con RV, c Diseño: sistema electrónico de adquisición y envío de datos. El dispositivo de inmersión captura los movimientos del brazo del operario, por medio de sensores; las señales suministradas por esto, son procesadas por un PIC, y enviadas al PC, para ser leídas por el software, que simula con realidad virtual el movimiento del manipulador UMNG-1. Finalmente, teniendo en cuenta la(s posición(es final deseada del efector final, es entregado un código, que enviado al controlador YASKAWA-SMC 2000, posibilita el movimiento real del UMNG-1, para llevar a cabo tareas de difícil ejecución.

  4. Condiciones térmicas de un dispositivo electrónico en caso de incendio Primera parte: estudio experimental

    Directory of Open Access Journals (Sweden)

    Bruno Chine

    2007-11-01

    Full Text Available En este trabajo se presentan los resultados de un estudio experimental para determinar las condiciones térmicas a la cual un sistema electrónico, usado para radiocomunicaciones en túneles, podría estar sujeto en caso de incendio. El sistema se compone de un dispositivo electrónico contenido en una caja metálica de acero inoxidable 316, un cable coaxial interno y un cable coaxial externo de cobre. Sobre el sistema, que se alberga en una cámara de polímero concreto, ha sido realizada una prueba al fuego con registro experimental de los valores de temperatura en diferentes puntos del sistema mismo. El trabajo experimental ha permitido analizar eficazmente la respuesta del dispositivo electrónico y de los distintos materiales que lo componen a las severas condiciones térmicas de prueba.

  5. Conceptual source design and dosimetric feasibility study for intravascular treatment: a proposal for intensity modulated brachytherapy

    International Nuclear Information System (INIS)

    Kim, Si Yong; Han, Eun Young; Palta, Jatinder R.; Ha, Sung W.

    2003-01-01

    To propose a conceptual design of a novel source for intensity modulated brachytherapy. The source design incorporates both radioactive and shielding materials (stainless steel or tungsten), to provide an asymmetric dose intensity in the azimuthal direction. The intensity modulated intravascular brachytherapy was performed by combining a series of dwell positions and times, distributed along the azimuthal coordinates. Two simple designs for the beta-emitting sources, with similar physical dimensions to a 90 Sr/Y Novoste Beat-Cath source, were considered in the dosimetric feasibility study. In the first design, the radioactive and materials each occupy half of the cylinder and in the second, the radioactive material occupies only a quarter of the cylinder. The radial and azimuthal dose distributions around each source were calculated using the MCNP Monte Carlo code. The preliminary hypothetical simulation and optimization results demonstrated the 87% difference between the maximum and minimum doses to the lumen wall, due to off-centering of the radiation source, could be reduced to less than 7% by optimizing the azimuthal dwell positions and times of the partially shielded intravascular brachytherapy sources. The novel brachytherapy source design, and conceptual source delivery system, proposed in this study show promising dosimetric characteristics for the realization of intensity modulated brachytherapy in intravascular treatment. Further development of this concept will center on building a delivery system that can precisely control the angular motion of a radiation source in a small-diameter catheter

  6. Disseminated intravascular coagulation caused by moojenactivase, a procoagulant snake venom metalloprotease.

    Science.gov (United States)

    Sartim, Marco A; Cezarette, Gabriel N; Jacob-Ferreira, Anna L; Frantz, Fabiani G; Faccioli, Lucia H; Sampaio, Suely V

    2017-10-01

    Snake venom toxins that activate coagulation factors are key players in the process of venom-induced coagulopathy, and account for severe clinical manifestations. The present study applies a variety of biochemical, hematological, and histopathological approaches to broadly investigate the intravascular and systemic effects of moojenactivase (MooA), the first described PIIId subclass metalloprotease isolated from Bothrops sp. venom that activates coagulation factors. MooA induced consumption coagulopathy with high toxic potency, characterized by prolongation of prothrombin and activated partial thromboplastin time, consumption of fibrinogen and the plasma coagulation factors X and II, and thrombocytopenia. MooA promoted leukocytosis and expression of the proinflammatory cytokines interleukin-6 and tumor necrosis factor-α, accompanied by tissue factor-dependent procoagulant activity in peripheral blood mononuclear cells. This metalloprotease also caused intravascular hemolysis, elevated plasma levels of creatine kinase-MB, aspartate transaminase, and urea/creatinine, and induced morphopathological alterations in erythrocytes, heart, kidney, and lungs associated with thrombosis and hemorrhage. Diagnosis of MooA-induced disseminated intravascular coagulation represents an important approach to better understand the pathophysiology of Bothrops envenomation and develop novel therapeutic strategies targeting hemostatic disturbances. Copyright © 2017. Published by Elsevier B.V.

  7. Cardiovascular disease in haemodialysis: role of the intravascular innate immune system.

    Science.gov (United States)

    Ekdahl, Kristina N; Soveri, Inga; Hilborn, Jöns; Fellström, Bengt; Nilsson, Bo

    2017-05-01

    Haemodialysis is a life-saving renal replacement modality for end-stage renal disease, but this therapy also represents a major challenge to the intravascular innate immune system, which is comprised of the complement, contact and coagulation systems. Chronic inflammation is strongly associated with cardiovascular disease (CVD) in patients on haemodialysis. Biomaterial-induced contact activation of proteins within the plasma cascade systems occurs during haemodialysis and initially leads to local generation of inflammatory mediators on the biomaterial surface. The inflammation is spread by soluble activation products and mediators that are generated during haemodialysis and transported in the extracorporeal circuit back into the patient together with activated leukocytes and platelets. The combined effect is activation of the endothelium of the cardiovascular system, which loses its anti-thrombotic and anti-inflammatory properties, leading to atherogenesis and arteriosclerosis. This concept suggests that maximum suppression of the intravascular innate immune system is needed to minimize the risk of CVD in patients on haemodialysis. A potential approach to achieve this goal is to treat patients with broad-specificity systemic drugs that target more than one of the intravascular cascade systems. Alternatively, 'stealth' biomaterials that cause minimal cascade system activation could be used in haemodialysis circuits.

  8. Intravascular pulmonary metastases from sarcoma: appearance on computed tomography in 3 cases

    International Nuclear Information System (INIS)

    Ting, P.T.; Burrowes, P.W.; Gray, R.R.

    2005-01-01

    Various common malignant neoplasms (ie, liver, kidney, stomach and breast) have been reported to embolize to the pulmonary arterial system. This uncommon occurrence can also result from metastatic sarcoma. We report 3 cases- 2 chondrosarcomas and 1 osteosarcoma-associated with intravascular motastases to the pulmonary vasculature and discuss the clinical presentation and differentiating radiologic features on computed tomography (CT). Intravascular pulmonary tumour emboli may present with nonspecific respiratory symptoms or remain completely asymptomatic, and therefore, many patients are often misdiagnosed with thromboembolic disease or undiagnosed until autopsy. Chest CTs in all our patients demonstrated a striking pattern of multifocal tubular branching beaded opacities along the pulmonary vasculature in a multilobular distribution. Our observations and a review of the literature indicate that chest CT is the most useful diagnostic tool for detecting intravascular pulmonary tumour emboli. CT can distinguish this entity from mucous plugging by demonstrating the normal adjacent bronchus. The tubular nature of these metastases distinguishes them from the more common parenchymal metastases. (author)

  9. The lateral neostriatum is necessary for compensatory ingestive behaviour after intravascular dehydration in female rats.

    Science.gov (United States)

    Lelos, M J; Harrison, D J; Rosser, A E; Dunnett, S B

    2013-12-01

    Aberrant striatal function results in an array of physiological symptoms, including impaired consummatory and regulatory behaviours, which can lead to weight loss and dehydration. It was hypothesised, therefore, that cell loss in the neostriatum may contribute to altered fluid intake by regulating physiological signals related to dehydration status. To test this theory, rats with lesions of the lateral neostriatum and sham controls underwent a series of physiological challenges, including the experimental induction of intracellular and intravascular dehydration. No baseline differences in prandial or non-prandial drinking were observed, nor were differences in locomotor activity evident between groups. Furthermore, intracellular dehydration increased water intake in lesion rats in a manner comparable to sham rats. Interestingly, a specific impairment was evident in lesion rats after subcutaneous injection of poly-ethylene glycol was used to induce intravascular dehydration, such that lesion rats failed to adapt their water intake to this physiological change. The results suggest that the striatal lesions resulted in regulatory dysfunction by impairing motivational control over compensatory ingestive behaviour after intravascular hydration, while the physiological signals related to dehydration remain intact. Loss of these cells in neurodegenerative disorders, such Huntington's disease, may contribute to regulatory changes evident in the course of the disease. Copyright © 2013 Elsevier Ltd. All rights reserved.

  10. Conceptual source design and dosimetric feasibility study for intravascular treatment: a proposal for intensity modulated brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Si Yong; Han, Eun Young; Palta, Jatinder R. [College of Medicine, Florida Univ., Florida (United States); Ha, Sung W. [College of Medicine, Seoul National Univ., Seoul (Korea, Republic of)

    2003-06-01

    To propose a conceptual design of a novel source for intensity modulated brachytherapy. The source design incorporates both radioactive and shielding materials (stainless steel or tungsten), to provide an asymmetric dose intensity in the azimuthal direction. The intensity modulated intravascular brachytherapy was performed by combining a series of dwell positions and times, distributed along the azimuthal coordinates. Two simple designs for the beta-emitting sources, with similar physical dimensions to a {sub 90}Sr/Y Novoste Beat-Cath source, were considered in the dosimetric feasibility study. In the first design, the radioactive and materials each occupy half of the cylinder and in the second, the radioactive material occupies only a quarter of the cylinder. The radial and azimuthal dose distributions around each source were calculated using the MCNP Monte Carlo code. The preliminary hypothetical simulation and optimization results demonstrated the 87% difference between the maximum and minimum doses to the lumen wall, due to off-centering of the radiation source, could be reduced to less than 7% by optimizing the azimuthal dwell positions and times of the partially shielded intravascular brachytherapy sources. The novel brachytherapy source design, and conceptual source delivery system, proposed in this study show promising dosimetric characteristics for the realization of intensity modulated brachytherapy in intravascular treatment. Further development of this concept will center on building a delivery system that can precisely control the angular motion of a radiation source in a small-diameter catheter.

  11. Pulsed arterial spin labeling using TurboFLASH with suppression of intravascular signal.

    Science.gov (United States)

    Pell, Gaby S; Lewis, David P; Branch, Craig A

    2003-02-01

    Accurate quantification of perfusion with the ADC techniques requires the suppression of the majority of the intravascular signal. This is normally achieved with the use of diffusion gradients. The TurboFLASH sequence with its ultrashort repetition times is not readily amenable to this scheme. This report demonstrates the implementation of a modified TurboFLASH sequence for FAIR imaging. Intravascular suppression is achieved with a modified preparation period that includes a driven equilibrium Fourier transform (DEFT) combination of 90 degrees-180 degrees-90 degrees hard RF pulses subsequent to the inversion delay. These pulses rotate the perfusion-prepared magnetization into the transverse plane where it can experience the suitably placed diffusion gradients before being returned to the longitudinal direction by the second 90 degrees pulse. A value of b = 20-30 s/mm(2) was thereby found to suppress the majority of the intravascular signal. For single-slice perfusion imaging, quantification is only slightly modified. The technique can be readily extended to multislice acquisition if the evolving flow signal after the DEFT preparation is considered. An advantage of the modified preparation scheme is evident in the multislice FAIR images by the preservation of the sign of the magnetization difference. Copyright 2003 Wiley-Liss, Inc.

  12. An experimental method for detecting blood splatter from retractable phlebotomy and intravascular devices.

    Science.gov (United States)

    Haiduven, Donna; Applegarth, Shawn; Shroff, Miloni

    2009-03-01

    This study was designed to evaluate the safety of retractable intravascular devices in terms of their potential to produce blood splatter. A method for measuring this blood splatter designed by the research team was used to evaluate 3 specific intravascular devices. Scientific filters were positioned around the retraction mechanisms of the devices and weighed with an analytical scale, both before and after activation, in a simulated vein containing mock venous blood. The difference in filter mass was used as the primary unit of analysis to detect blood splatter. In addition, the filters were visually inspected for the presence or absence of blood. A paired t-test revealed significant differences in the prefilter and postfilter groups for 2 of the 3 devices tested (P blood was detected on 23% to 40% of the scientific filters for 2 of the devices. Our findings indicate a potential for bloodborne pathogen exposure with the use of intravascular devices with a retractable mechanism. This experiment may serve as a model in the design and implementation of future sharps device evaluation protocols to validate the threat of bloodborne pathogen exposure.

  13. Hydrophilic Polymer Embolism: Implications for Manufacturing, Regulation, and Postmarket Surveillance of Coated Intravascular Medical Devices.

    Science.gov (United States)

    Mehta, Rashi I; Mehta, Rupal I

    2018-03-19

    Hydrophilic polymers are ubiquitously applied as surface coatings on catheters and intravascular medical technologies. Recent clinical literature has heightened awareness on the complication of hydrophilic polymer embolism, the phenomenon wherein polymer coating layers separate from catheter and device surfaces, and may be affiliated with a range of unanticipated adverse reactions. Significant system barriers have limited and delayed reporting on this iatrogenic complication, the full effects of which remain underrecognized by healthcare providers and manufacturers of various branded devices. In 2015, the United States Food and Drug Administration acknowledged rising clinical concerns and stated that the agency would work with stakeholders to further evaluate gaps that exist in current national and international device standards for coated intravascular medical technologies. The present article reviews current knowledge on this complication as well as factors that played a role in delaying detection and dissemination of information and new knowledge once hazards and clinical risks were identified. Furthermore, organ-specific effects and adverse reaction patterns are summarized, along with implications for device manufacturing, safety assurance, and regulation. Qualitative and quantitative particulate testing are needed to optimize coated intravascular device technologies. Moreover, general enhanced processes for medical device surveillance are required for timely adverse event management and to ensure patient safety.

  14. DISPOSITIVO DE NAVEGACIÓN PARA PERSONAS INVIDENTES BASADO EN LA TECNOLOGÍA TIME OF FLIGHT

    Directory of Open Access Journals (Sweden)

    Ismael Lengua

    2013-01-01

    Las pruebas experimentales llevadas a cabo demuestran el potencial que puede tener para las personas invidentes. Se prueba que con la ayuda del dispositivo acústico los usuarios se sienten más seguros a la hora de transitar por las calles, debido a que tienen una amplia información sobre el entorno que los rodea, más allá de la obtenida con el bastón.

  15. Short Implants: New Horizon in Implant Dentistry.

    Science.gov (United States)

    Jain, Neha; Gulati, Manisha; Garg, Meenu; Pathak, Chetan

    2016-09-01

    The choice of implant length is an essential factor in deciding the survival rates of these implants and the overall success of the prosthesis. Placing an implant in the posterior part of the maxilla and mandible has always been very critical due to poor bone quality and quantity. Long implants can be placed in association with complex surgical procedures such as sinus lift and bone augmentation. These techniques are associated with higher cost, increased treatment time and greater morbidity. Hence, there is need for a less invasive treatment option in areas of poor bone quantity and quality. Data related to survival rates of short implants, their design and prosthetic considerations has been compiled and structured in this manuscript with emphasis on the indications, advantages of short implants and critical biomechanical factors to be taken into consideration when choosing to place them. Studies have shown that comparable success rates can be achieved with short implants as those with long implants by decreasing the lateral forces to the prosthesis, eliminating cantilevers, increasing implant surface area and improving implant to abutment connection. Short implants can be considered as an effective treatment alternative in resorbed ridges. Short implants can be considered as a viable treatment option in atrophic ridge cases in order to avoid complex surgical procedures required to place long implants. With improvement in the implant surface geometry and surface texture, there is an increase in the bone implant contact area which provides a good primary stability during osseo-integration.

  16. Infecciones intrahospitalarias asociadas a dispositivos invasivos en unidades de cuidados intensivos de un hospital nacional de Lima, Perú

    Directory of Open Access Journals (Sweden)

    Omayra Chincha

    2013-12-01

    Full Text Available Con el objetivo de describir la incidencia de infecciones intrahospitalarias asociadas a dispositivos invasivos en unidades de cuidados intensivos (UCI del Hospital Nacional Cayetano Heredia se realizó un estudio observacional retrospectivo utilizando datos de la Oficina de Epidemiología y Salud Ambiental durante los años 2010 al 2012. Se notificó un total de 222 infecciones intrahospitalarias, la UCI de Medicina tuvo la incidencia por 1000 días de uso del dispositivo más alta para neumonía asociada a ventilador mecánico (28,6; infección del torrente sanguíneo asociado a catéter venoso central (11,9, e infección del tracto urinario asociado a catéter (8,1. Los principales agentes infecciosos aislados fueron Pseudomona sp. (32,3% en la UCI de emergencia, Staphylococcus coagulasa negativo(36% en la UCI de medicina y Candida sp (69,2% en la UCI de cirugía. Las tasas de infecciones asociadas a dispositivos invasivos se reportaron altas semejantes a otros hospitales nacionales con limitados recursos e infraestructura

  17. Infecciones intrahospitalarias asociadas a dispositivos invasivos en unidades de cuidados intensivos de un hospital nacional de Lima, Perú

    Directory of Open Access Journals (Sweden)

    Omayra Chincha

    Full Text Available Con el objetivo de describir la incidencia de infecciones intrahospitalarias asociadas a dispositivos invasivos en unidades de cuidados intensivos (UCI del Hospital Nacional Cayetano Heredia se realizó un estudio observacional retrospectivo utilizando datos de la Oficina de Epidemiología y Salud Ambiental durante los años 2010 al 2012. Se notificó un total de 222 infecciones intrahospitalarias, la UCI de Medicina tuvo la incidencia por 1000 días de uso del dispositivo más alta para neumonía asociada a ventilador mecánico (28,6; infección del torrente sanguíneo asociado a catéter venoso central (11,9, e infección del tracto urinario asociado a catéter (8,1. Los principales agentes infecciosos aislados fueron Pseudomona sp. (32,3% en la UCI de emergencia, Staphylococcus coagulasa negativo(36% en la UCI de medicina y Candida sp (69,2% en la UCI de cirugía. Las tasas de infecciones asociadas a dispositivos invasivos se reportaron altas semejantes a otros hospitales nacionales con limitados recursos e infraestructura

  18. Notas sobre el uso del concepto de dispositivo para el análisis de programas sociales

    Directory of Open Access Journals (Sweden)

    Nicolás Santiago Dallorso

    2012-01-01

    Full Text Available El artículo realiza un acercamiento al concepto de dispositivo para indagar sus alcances y límites heurísticos para abordar el análisis de programas sociales. La noción de dispositivo permite explicar cómo las formaciones discursivas y los regímenes de visibilidad se articulan sin reducirse uno a otro; así como también se presenta como adecuado para comprender el acoplamiento entre relaciones de poder y formas de subjetivación. Al mismo tiempo, el concepto de dispositivo resulta conveniente para indagar el co-funcionamiento de dos dimensiones: la macropolítica, es decir, las relaciones políticas que se distinguen por constituir autoridades institucionalmente establecidas que se presentan como las únicas legalmente validadas y, por otro lado, la dimensión micropolítica, es decir, el dominio político de creencias y deseos en el que se instituyen autoridades menos burocratizadas, más dispersas e informales. En el trabajo realizamos una apropiación de este concepto para estudiar una política social llamada "de combate contra la pobreza".

  19. MONITORAMENTO DE PLATAFORMAS DE POÇOS DE PETRÓLEO ATRAVÉS DE DISPOSITIVOS MÓVEIS

    Directory of Open Access Journals (Sweden)

    Clayton Maciel Costa

    2012-06-01

    Full Text Available A expansão da Web, o advento das novas tecnologias de informação e comunicação e a massificação dos dispositivos móveis tornaram possíveis novas possibilidades de gerenciamento, interações e compartilhamento de informações. Na área petrolífera, sistemas de monitoramento utilizando dispositivos móveis vêm sendo utilizados para otimização de processos, monitoramento de dados, geração de relatórios, geração de alertas e identificação de falhas em tempo-real nas plataformas petrolíferas. Contudo, ainda são poucos os sistemas que identificam problemas em tempo-real, já que a maioria não emprega técnicas de sistemas de tempo-real. Este artigo propõe o sistema SiMoS, um sistema de tempo-real para o monitoramento remoto de plataformas de poços de petróleo através de dispositivos móveis.

  20. Técnicas de análisis forense digital aplicadas a dispositivos y sistemas móviles

    Directory of Open Access Journals (Sweden)

    Guillermo Jaramillo Cabrera

    2011-12-01

    Full Text Available La disciplina del Análisis Forense Digital, es un campo de investigación excitante y dinámico, conocido hasta ahora sólo por especialistas, y tiene cada vez más un poderoso impacto en una variedad de situaciones, incluyendo ambientes corporativos, investigaciones internas, litigación civil, investigaciones criminales, investigaciones de inteligencia y asuntos de seguridad nacional. El Análisis Forense Digital Móvil, es sin duda, el de mayor crecimiento y desarrollo en la disciplina forense digital y ofrece ventajas significativas así como también muchos retos. Mientras que lo interesante de la investigación forense de dispositivos como los que usan el Sistema Operativo Móvil Android o simplemente dispositivo Android, implica la adquisición y análisis de datos; es importante tener una visión amplia tanto de la plataforma como de las herramientas que serán utilizadas a lo largo de la investigación. Un entendimiento minucioso asistirá al Ingeniero Examinador Forense o Ingeniero de Seguridad a través del análisis e investigación exitosos de dispositivos móviles, incluyendo los Smartphone basados en Android.

  1. Modelado Dinámico y Control de un Dispositivo Sumergido Provisto de Actuadores Hidrostáticos

    Directory of Open Access Journals (Sweden)

    Marina Pérez de la Portilla

    2017-12-01

    Full Text Available Las corrientes marinas, fuente de energía renovable más predecible, localizan la mayor parte de su energía en altas profundidades. Para aprovechar esta energía se están desarrollando dispositivos flotantes, de tipo fondeado. La viabilidad económica de estos dispositivos requiere el abaratamiento de costos. El desarrollo de sistemas de control que permitan el cambio automático de orientación y profundidad del generador, con el fin de abaratar las maniobras de mantenimiento y aprovechar el recurso energético de forma óptima, resulta imprescindible. En este trabajo se presenta un actuador hidrostático y se realiza un modelo dinámico simple para control, de un dispositivo de dos grados de libertad, con un sistema de control de lastre. A partir de este modelo se ha desarrollado una ley de control multivariable, basada en una matriz de desacoplamiento no lineal y en la compensación de los términos de fricción y compresibilidad. Finalmente, la bondad del controlador ha sido validada mediante simulación.

  2. Pasado, presente y futuro cercano de los materiales para uso en implantes óseos biodegradables

    OpenAIRE

    Plazas Bonilla, Clara Eugenia; Perilla, Jairo Ernesto

    2011-01-01

    El manejo de fracturas y defectos óseos procura la regeneración del tejido óseo respetando su anatomía y buscando recuperar su funcionalidad. El logro de este objetivo se inició en el siglo XVII con el uso de injertos de origen animal o humano, y ha llegado en la actualidad al uso de implantes, dispositivos elaborados en materiales naturales o sintéticos que comportan una gran variedad de propiedades químicas, físicas y biológicas. Las investigaciones en el área continúan encaminándose a la s...

  3. A TACTILIDADE EM DISPOSITIVOS MÓVEIS: PRIMEIRAS REFLEXÕES E ENSAIO DE TIPOLOGIAS

    Directory of Open Access Journals (Sweden)

    PALACIOS, Marcos Silva

    2012-12-01

    Full Text Available Seis propriedades fundamentais caracterizam os espaços de informação jornalística na internet: hipertextualidade, interatividade, multimidialidade ou convergência, personalização, atualização contínua e memória. A introdução dos smartphones e tablets produziu o surgimento de um novo elemento que se soma às características anteriores: a tactilidade. Antes ligada apenas a recursos de acessibilidade para deficientes visuais, tornou-se elemento essencial na comunicação em dispositivos móveis com tela sensível ao toque. Pesquisas na área da tecnologia háptica abrem mais perspectivas para apresentação e consumo de informação. Este artigo discute aspectos gerais da tactilidade, como característica a ser pesquisada e experimentada, assinala alguns exemplos de uso, propõe uma tipologia preliminar para as diversas formas de sua operacionalização. Uma breve aproximação ao uso jornalístico das interfaces hápticas complementa o artigo.

  4. Gestor de aprendizaje para la experimentación remota con dispositivos optoelectrónicos

    Directory of Open Access Journals (Sweden)

    Duván Fernando García-Cedeño

    2015-01-01

    Full Text Available La internet y las tecnologías de la información y comunicacione s – TIC- están realizando un aporte muy valioso a la educación. La experimentación remota es una muestra de ese aporte que surge c omo solución a diversos inconvenientes presentes con las prácti cas presenciales, las cuales son un aspecto fundamental en el desar rollo de competencias en la educación en ingeniería. En este tr abajo se ha implementado un gestor de aprendizaje para la experimentación c on dispositivos optoelectrónicos, el cual está compuesto por un a plataforma hardware que consta d e un conjunto de componentes el ectrónicos como diodos emisores de luz y optoacopladores, cada uno con su respectiva interfaz de aco ndicionamiento de señal y comu nicación con el servidor; adici onalmente, se desarrolló una int erfaz de usuario que incluye utilitarios de la WEB 2.0 y conceptos de si stemas gestores de aprendizaje y contenido, facilitando su admi nistración y promoviendo el aprendizaj e colaborativo con el uso de redes soc iales.

  5. Monitorización de Signos Vitales Mediante una Red de Dispositivos Móviles

    Directory of Open Access Journals (Sweden)

    Daniel Cilio

    2013-11-01

    Full Text Available El desarrollo e implementación de diferentes proyectos tecnológicos, apoyados en el correspondiente conocimiento médico, pueden contribuir a resolver varios problemas del sector de la salud. Si bien en los últimos años se han realizado enormes esfuerzos para desarrollar tecnologías aplicables en ambientes clínicos, el desarrollo de tecnologías para atención médica domiciliar podría reducir la presión que agobia a los hospitales actualmente. En el presente proyecto se realiza el diseño e implementación de un sistema para monitorización de signos vitales, el cual mide la frecuencia cardiaca, la oxigenación sanguínea y la temperatura corporal de una persona. La información obtenida de cada signo vital es muestreada y procesada por una plataforma digital para posteriormente ser enviada mediante un módulo Bluetooth hacia un dispositivo móvil para su análisis y visualización. El prototipo fue evaluado mediante una batería de pruebas para medición de signos vitales en diferentes pacientes.

  6. Hepatectomia videolaparoscópica com dispositivo de radiofrequência

    Directory of Open Access Journals (Sweden)

    Vivian Resende

    Full Text Available As ressecções hepáticas laparoscópicas vêm ganhando adeptos entre cirurgiões pois evidenciam recuperação rápida, menor permanência hospitalar e melhor resultado estético. A utilização do dispositivo laparoscópico de radiofreqüência foi pela primeira vez utilizada, com sucesso, no Brasil, para a ressecção de carcinoma hepatocelular no segmento VI, em dois pacientes cirróticos. Apesar do sangramento intraoperatório continuar sendo um grande desafio para o cirurgião durante ressecções hepáticas laparoscópicas, em ambos os casos, a exclusão vascular hepática foi dispensável e não houve necessidade de hemotransfusão. Os pacientes receberam alta hospitalar no quarto dia pós-operatório.

  7. Dispositivos reductores de velocidad vehicular: Hacia el desarrollo de nuevos diseños

    Directory of Open Access Journals (Sweden)

    Fredy Alberto Guío Burgo

    2010-12-01

    Full Text Available Expone  el  resultado  de  varias  pruebas  de  campo realizadas a dos dispositivos reductores de velocidad vehicular,  basados  en  la  generación  de  ilusiones  o efectos ópticos, que inducen al conductor a disminuir la velocidad de marcha; se evaluó el desempeño de los diseños mediante estudios de velocidad de punto del  tipo  antes  y  después, mediante  pruebas  dehipótesis  estadísticas  que  demostraron  que  la reducción obtenida fue significativa para la mayoría de  los  usuarios, excepto  algunas  categorías  de vehículos. Los resultados obtenidos son alentadores; se espera que en próximos estudios se logren definir las  características óptimas de un diseño que pueda ser  implementado en las carreteras colombianas.

  8. Implantation, recoil implantation, and sputtering

    International Nuclear Information System (INIS)

    Kelly, R.

    1984-01-01

    Underlying ion-beam modification of surfaces is the more basic subject of particle-surface interaction. The ideas can be grouped into forward and backward features, i.e. those affecting the interior of the target and those leading to particle expulsion. Forward effects include the stopping of the incident particles and the deposition of energy, both governed by integral equations which are easily set up but difficult to solve. Closely related is recoil implantation where emphasis is placed not on the stopping of the incident particles but on their interaction with target atoms with resulting implantation of these atoms. Backward effects, all of which are denoted as sputtering, are in general either of collisional, thermal, electronic, or exfoliational origin. (Auth.)

  9. Dental Implant Surgery

    Science.gov (United States)

    ... here to find out more. Dental Implant Surgery Dental Implant Surgery Dental implant surgery is, of course, ... to find out more. Wisdom Teeth Management Wisdom Teeth Management An impacted wisdom tooth can damage neighboring ...

  10. Cochlear Implant

    Directory of Open Access Journals (Sweden)

    Mehrnaz Karimi

    1992-04-01

    Full Text Available People with profound hearing loss are not able to use some kinds of conventional amplifiers due to the nature of their loss . In these people, hearing sense is stimulated only when the auditory nerve is activated via electrical stimulation. This stimulation is possible through cochlear implant. In fact, for the deaf people who have good mental health and can not use surgical and medical treatment and also can not benefit from air and bone conduction hearing aids, this device is used if they have normal central auditory system. The basic parts of the device included: Microphone, speech processor, transmitter, stimulator and receiver, and electrode array.

  11. Complications after cardiac implantable electronic device implantations

    DEFF Research Database (Denmark)

    Kirkfeldt, Rikke Esberg; Johansen, Jens Brock; Nohr, Ellen Aagaard

    2013-01-01

    Complications after cardiac implantable electronic device (CIED) treatment, including permanent pacemakers (PMs), cardiac resynchronization therapy devices with defibrillators (CRT-Ds) or without (CRT-Ps), and implantable cardioverter defibrillators (ICDs), are associated with increased patient...

  12. 164. Extracción endovascular de dispositivos cardíacos infectados

    OpenAIRE

    Gutiérrez Carretero, E.; Hernández Fernández, A.; Borrego Domínguez, J.M.; Alarcón, A.; Eslava, J.; Bibiloni Lage, I.; Ruiz Solano, E.; Romero Rodríguez, N.

    2010-01-01

    La tasa de infección publicada en la literatura para implantes de marcapasos y desfibriladores es del 1-7%, siendo en nuestro hospital de 1,5% para marcapasos y 3% para desfibrilador automático implantable (DAI), con una mortalidad del 10%. En un estudio realizado por la Sociedad Andaluza de Enfermedades Infecciosas sobre seis hospitales andaluces, se han detectado 243 infecciones de MP/DAI entre 1998-2008, de las cuales un 44,5% han sido infecciones locales y en un 55,5% infecciones sistémic...

  13. Cutaneous and systemic hypersensitivity reactions to metallic implants.

    Science.gov (United States)

    Basko-Plluska, Juliana L; Thyssen, Jacob P; Schalock, Peter C

    2011-01-01

    Cutaneous reactions to metal implants, orthopedic or otherwise, are well documented in the literature. The first case of a dermatitis reaction over a stainless steel fracture plate was described in 1966. Most skin reactions are eczematous and allergic in nature, although urticarial, bullous, and vasculitic eruptions may occur. Also, more complex immune reactions may develop around the implants, resulting in pain, inflammation, and loosening. Nickel, cobalt, and chromium are the three most common metals that elicit both cutaneous and extracutaneous allergic reactions from chronic internal exposure. However, other metal ions as well as bone cement components can cause such hypersensitivity reactions. To complicate things, patients may also develop delayed-type hypersensitivity reactions to metals (ie, in-stent restenosis, prosthesis loosening, inflammation, pain, or allergic contact dermatitis) following the insertion of intravascular stents, dental implants, cardiac pacemakers, or implanted gynecologic devices. Despite repeated attempts by researchers and clinicians to further understand this difficult area of medicine, the association between metal sensitivity and cutaneous allergic reactions remains to be fully understood. This review provides an update of the current knowledge in this field and should be valuable to health care providers who manage patients with conditions related to this field.

  14. Dispositivos de controle e gestão de violências na contemporaneidade

    Directory of Open Access Journals (Sweden)

    Bonamigo, Irme Salete

    2009-01-01

    Full Text Available Este artigo discute o controle e a gestão de violências na contemporaneidade a partir das políticas sociais de segurança Programa Tolerância Zero e Polícia Comunitária, emergentes em Chapecó (SC nesta década, analisando discursos e práticas implicados e efeitos decorrentes. A pesquisa articulou princípios da postura etnográfica com fundamentos da Teoria Ator-Rede. Foram realizadas 80 entrevistas com moradores e pessoas de diversas entidades locais, pesquisa documental, pesquisa hemerográfica e observação participante com registro em diário de campo. Apesar de as políticas sociais se sustentarem em lógicas diferenciadas, constatou-se a predominância de práticas e discursos de punição e repressão, mostrando a presença do Estado Penal, discutido por Loïc Wacquant, mais preocupado com a segurança criminal do que com a segurança social. Evidenciou-se a necessidade de desnaturalização desses dispositivos de controle e de criação de estratégias participativas na definição e acompanhamento das ações de segurança, podendo a psicologia contribuir nesse processo com estudos e intervenções

  15. Nomogramas para ensamble y uso de la Inyectora Unidrench® de dispositivo venturi

    Directory of Open Access Journals (Sweden)

    Villalobos Roberto

    2010-08-01

    Full Text Available El término drench se refiere a la incorporación al suelo de un agroquímico en solución con el riego. Basada en un dispositivo venturi, Unidrench® es una inyectora desarrollada para aplicar este tipo de productos en áreas cultivadas en camas con especies como flores, hierbas aromáticas, hortalizas, etc. Operando con cualquier hidrante que suministre agua a presión, la inyectora permite realizar aplicaciones eficientes a través de sistemas de riego manual con manguera, empleando boquillas denominadas de acuerdo a su forma como cacho, codo, poma, flauta, y otras. Como las especificaciones del equipo se ajustan según las necesidades del usuario, el objetivo de esta investigación consistió en la caracterización hidráulica de la inyectora Unidrench ® y la construcción de sus nomogramas de desempeño. En el Laboratorio de Hidráulica de la Universidad Nacional de Colombia, sede Bogotá, se probaron diferentes especificaciones, así: i para cinco tipos de boquilla (descarga libre, cacho doble, flauta y poma doble de 400 y 1.000 huecos, se determinaron tanto caudales de riego como de inyección; ii se probaron dos longitudes (50 y 75 m de manguera de PVC; iii tanto en esta última como en los inyectores venturi que utiliza el sistema se ensayaron diámetros de 1,9 y 2,54 cm (¾ y 1 pulgada; y iv los reguladores de presión se evaluaron a seis niveles diferentes (15, 20, 25, 30, 35 y 40 PSI . Para facilitar la utilización del equipo se incluyen sus instrucciones de operación.

  16. Slow clearance gadolinium-based extracellular and intravascular contrast media for three-dimensional MR angiography.

    Science.gov (United States)

    Bremerich, J; Colet, J M; Giovenzana, G B; Aime, S; Scheffler, K; Laurent, S; Bongartz, G; Muller, R N

    2001-04-01

    The objective of this study was to assess two new slow-clearance contrast media with extracellular and intravascular distribution for magnetic resonance angiography (MRA). Extracellular Gd-DTPA-BC(2)glucA and intravascular Gd(DO3A)(3)-lys(16) were developed within the European Biomed2 MACE Program and compared with two reference compounds, intravascular CMD-A2-Gd-DOTA and extracellular GdDOTA, in 12 rats. Pre- and post-contrast three-dimensional MR (TR/TE = 5 msec/2.2 msec; isotropic voxel size 0.86 mm(3)) was acquired for 2 hours. Signal-to-noise enhancement (DeltaSNR) was calculated. Two minutes after injection, all contrast media provided strong vascular signal enhancement. The DeltaSNR for Gd-DTPA-BC(2)glucA, Gd(DO3A)(3)-lys(16), CMD-A2-Gd-DOTA, and GdDOTA were 13.0 +/- 1.8, 25.0 +/- 3.2, 25.0 +/- 4.0, and 18.0 +/- 3.4, respectively. Gd-DTPA-BC(2)glucA, Gd(DO3A)(3)-lys(16), and CMD-A2-Gd-DOTA cleared slowly from the circulation, whereas GdDOTA cleared rapidly. Vascular DeltaSNR at 2 hours were 2.9 +/- 0.6, 25.0 +/- 3.2, 25.0 +/- 4.0, and 0.4 +/- 1.0. Gd(DO3A)(3)-lys(16) provided strong vascular and minor background enhancement, and thus may be useful for MRA or perfusion imaging. Gd-DTPA-BC(2)glucA produces persistent enhancement of extracellular water, and thus may allow quantification of extracellular distribution volume and assessment of myocardial viability.

  17. Polymer coating embolism from intravascular medical devices - a clinical literature review.

    Science.gov (United States)

    Chopra, Amitabh M; Mehta, Monik; Bismuth, Jean; Shapiro, Maksim; Fishbein, Michael C; Bridges, Alina G; Vinters, Harry V

    Over the past three decades, lubricious (hydrophobic and/or hydrophilic) polymer-coated devices have been increasingly adopted by interventional physicians and vascular surgeons to access and treat a wider range of clinical presentations. Recent clinical literature highlights the presence of polymer coating emboli within the anatomy - a result of coating separation from an intravascular device - and associates it with a range of adverse clinical sequelae. The 2015 U.S. Food and Drug Administration safety communication titled "Lubricious Coating Separation from Intravascular Medical Devices" acknowledges these concerns and concludes that it will work with stakeholders to develop nonclinical test methodologies, establish performance criteria, and identify gaps in current national and international device standards for coating integrity performance. Despite this communication and multiple case reports from interventional physicians, pathologists, dermatologists and other involved physician specialties, polymer coating embolism remains clinically underrecognized. This article consolidates the available literature on polymer coating embolism (1986-2016) and highlights the following relevant information for the physician: (a) the history and elusive nature of polymer coating embolism; (b) potential incidence rates of this phenomenon; (c) reported histologic findings and clinical effects of polymer emboli in the anatomy; (d) the importance of the collaborative clinician-pathologist partnership to report polymer embolism findings; and (e) the importance to study particulate release from intravascular devices so as to further understand and potentially evolve coated interventional technologies. Preliminary research on coatings highlights the potential of using iterations of coatings on medical devices that attain the desired therapeutic result and mitigate or eliminate particulates altogether. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Management of subarachnoid hemorrhage classified grade V. Possibility of intravascular treatment

    Energy Technology Data Exchange (ETDEWEB)

    Uzura, Masahiko; Oshima, Kousuke; Morishima, Hiroyuki; Uchida, Kazuyoshi; Watanabe, Hiroyuki; Nakamura, Homare; Tanaka, Katsuyuki; Sekino, Hiroaki; Akashi, Katsuya [St. Marianna Univ., Kawasaki, Kanagawa (Japan). School of Medicine

    2001-10-01

    Management outcomes in poor-grade patients (World Federation of Neurological Surgeons Committee on a Universal Subarachnoid Hemorrhage Grading Scale Grade V) with ruptured cerebral aneurysms have historically been unsatisfactory. In the present study, we examined the possibility of intravascular treatment for ruptured aneurysm detected by 3-Dimensional CT angiography (3D-CTA) in poor-grade SAH patients. From April 1997 to July 2000, 3D-CTA was performed on 54 of 73 patients admitted with Grade V subarachnoid hemorrhage (SAH). Excluding 3 patients who underwent emergency surgery for ruptured aneurysms and intracerebral hematomas, CT findings from the remaining 51 patients were analyzed. The study included 23 men and 28 women, ranging in age from 28 to 91 with an average age of 63.6. The patients' initial scores on the Glasgow Coma Scale upon admission were 3 in 36 patients (including 19 patients who had undergone cardio-pulmonary arrest), 4 in 11 patients, 5 in 2 patients, and 6 in 2 patients. Ruptured aneurysms responsible for SAH were clearly delineated in 41 aneurysms from 39 patients, with 32 aneurysms in the anterior circulation and 9 in the posterior circulation. Patients with Glasgow Coma Scale of 4 or higher whose score did not progressively decrease for 12 hours after symptom onset were considered for intravascular treatment. In our study, 4 of 39 patients (10.3%) met these criteria. Glasgow Outcome Scale results were good recovery in 1 case, moderate disability in 1 case, severe disability in 1 case, and death in the remaining 48 cases. These results suggest that the management course for poor-grade (WFNS Grade V) SAH patients who retain brain stem reflexes contain the following: identification of aneurysms by 3D-CTA, maintenance of adequate sedation and external drainage to treat acute hydrocephalus, continued minimum 12-hour observation, monitoring levels of consciousness where possible, and consideration of aggressive therapy including

  19. Ischemia monitoring in off-pump coronary artery bypass surgery using intravascular near-infrared spectroscopy

    Directory of Open Access Journals (Sweden)

    Zerkowski Hans-Reinhard

    2006-05-01

    Full Text Available Abstract Background In off-pump coronary artery bypass surgery, manipulations on the beating heart can lead to transient interruptions of myocardial oxygen supply, which can generate an accumulation of oxygen-dependent metabolites in coronary venous blood. The objective of this study was to evaluate the reliability of intravascular near-infrared spectroscopy as a monitoring method to detect possible ischemic events in off-pump coronary artery bypass procedures. Methods In 15 elective patients undergoing off-pump myocardial revascularization, intravascular near-infrared spectroscopic analysis of coronary venous blood was performed. NIR signals were transferred through a fiberoptic catheter for signal emission and collection. For data analysis and processing, a miniature spectrophotometer with multivariate statistical package was used. Signal acquisition and analysis were performed before and after revascularization. Spectroscopic data were compared with hemodynamic parameters, electrocardiogram, transesophageal echocardiography and laboratory findings. Results A conversion to extracorporeal circulation was not necessary. The mean number of grafts per patient was 3.1 ± 0.6. An intraoperative myocardial ischemia was not evident, as indicated by electrocardiogram and transesophageal echocardiography. Continuous spectroscopic analysis showed reproducible absorption spectra of coronary sinus blood. Due to uneventful intraoperative courses, clear ischemia-related changes could be detected in none of the patients. Conclusion Our initial results show that intravascular near-infrared spectroscopy can reliably be used for an online intraoperative ischemia monitoring in off-pump coronary artery bypass surgery. However, the method has to be further evaluated and standardized to determine the role of spectroscopy in off-pump coronary artery bypass surgery.

  20. Intravascular ultrasonic-photoacoustic (IVUP) endoscope with 2.2-mm diameter catheter for medical imaging.

    Science.gov (United States)

    Bui, Nhat Quang; Hlaing, Kyu Kyu; Nguyen, Van Phuc; Nguyen, Trung Hau; Oh, Yun-Ok; Fan, Xiao Feng; Lee, Yong Wook; Nam, Seung Yun; Kang, Hyun Wook; Oh, Junghwan

    2015-10-01

    Intravascular ultrasound (IVUS) imaging is extremely important for detection and characterization of high-risk atherosclerotic plaques as well as gastrointestinal diseases. Recently, intravascular photoacoustic (IVPA) imaging has been used to differentiate the composition of biological tissues with high optical contrast and ultrasonic resolution. The combination of these imaging techniques could provide morphological information and molecular screening to characterize abnormal tissues, which would help physicians to ensure vital therapeutic value and prognostic significance for patients before commencing therapy. In this study, integration of a high-frequency IVUS imaging catheter (45MHz, single-element, unfocused, 0.7mm in diameter) with a multi-mode optical fiber (0.6mm in core diameter, 0.22 NA), an integrated intravascular ultrasonic-photoacoustic (IVUP) imaging catheter, was developed to provide spatial and functional information on light distribution in a turbid sample. Simultaneously, IVUS imaging was co-registered to IVPA imaging to construct 3D volumetric sample images. In a phantom study, a polyvinyl alcohol (PVA) tissue-mimicking arterial vessel phantom with indocyanine green (ICG) and methylene blue (MB) inclusion was used to demonstrate the feasibility of mapping the biological dyes, which are used in cardiovascular and cancer diagnostics. For the ex vivo study, an excised sample of pig intestine with ICG was utilized to target the biomarkers present in the gastrointestinal tumors or the atherosclerotic plaques with the proposed hybrid technique. The results indicated that IVUP endoscope with the 2.2-mm diameter catheter could be a useful tool for medical imaging. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. Rash, disseminated intravascular coagulation and legionella: Episode 10 and a rewind into the past

    Directory of Open Access Journals (Sweden)

    Prashanth M. Thalanayar

    2015-01-01

    Full Text Available Legionella pneumophila is the most common cause of legionellosis and is one of the organisms causing atypical pneumonia. We report the presentation of disseminated intravascular coagulation (DIC and skin rash in a single case of severe Legionella pneumonia. The unique clinical presentation of a diffuse rash diagnosed as purpura fulminans and the unpredictable variations encountered during the diagnostic work-up of the case make this write-up crucial. This article synthesizes all reported cases of L. pneumonia associated with cutaneous manifestations as well as cases presenting with DIC. Furthermore, this manuscript illustrates the correlation between cutaneous and coagulopathic manifestations, and morbidity and mortality from L. pneumonia.

  2. Fatal Klebsiella pneumoniae meningitis and concomitant disseminated intravascular coagulation in a patient with diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Ho Min-Po

    2009-01-01

    Full Text Available Bacterial meningitis remains a major cause of death and long-term neurologic sequelae worldwide. We present a case of fatal Klebsiella pneumoniae meningitis and concomitant disseminated intravascular coagulation (DIC in a 72-year-old woman with diabetes mellitus (DM. Both blood and cerebrospinal fluid cultures grew Klebsiella pneumoniae . Due to advanced age, newly recognized DM, K. pneumoniae bacteremia, and DIC, the prognosis of our patient was poor. Eight hours after arrival to the emergency department, cardiopulmonary resuscitation was necessary in this patient, but she died despite an early diagnosis and appropriate antibiotic therapy.

  3. Acute kidney injury and disseminated intravascular coagulation due to mercuric chloride poisoning

    Directory of Open Access Journals (Sweden)

    J Dhanapriya

    2016-01-01

    Full Text Available Mercury is a toxic heavy metal and occurs in organic and inorganic forms. Inorganic mercury includes elemental mercury and mercury salts. Mercury salts are usually white powder or crystals, and widely used in indigenous medicines and folk remedies in Asia. Inorganic mercury poisoning causes acute kidney injury (AKI and gastrointestinal manifestations and can be life-threatening. We describe a case with unknown substance poisoning who developed AKI and disseminated intravascular coagulation (DIC. Renal biopsy showed acute tubular necrosis. Later, the consumed substance was proven to be mercuric chloride. His renal failure improved over time, and his creatinine normalized after 2 months.

  4. Disseminated intravascular coagulation in a patient with metastatic prostate cancer: Fatal outcome following strontium-89 therapy

    Energy Technology Data Exchange (ETDEWEB)

    Leong, C.; McKenzie, R.; Coupland, D.B. [Univ. of British Columbia, (Canada)] [and others

    1994-10-01

    A patient with metastatic prostate cancer was found to have low-grade disseminated intravascular coagulation (DIC). He had significant bone pain despite external-beam radiotherapy and was given {sup 89}Sr with subsequent thrombocytopenia and epistaxis. The patient died from generalized hemorrhage 36 days postinjection. Although it is not possible to establish a causal relationship between {sup 89}Sr and DIC, practitioners should be alert to complications associated with the primary disorder which might occur at a time to raise concern about the intervention. 8 refs., 1 tab.

  5. [Intravascular Hemolysis Caused by Stenosis of an Elephant Trunk;Report of a Case].

    Science.gov (United States)

    Takamaru, Rikako; Kawahito, Koji; Aizawa, Kei; Misawa, Yoshio

    2017-07-01

    Symptomatic intravascular hemolysis after prosthetic aortic graft replacement is rare. It is primarily attributed to mechanical injury of red blood cells caused by stenosis of the vascular graft. A 50-year-old man presented with hemolytic anemia, 5 years after total arch replacement with an elephant trunk for type A aortic dissection. The hemolysis was caused by graft stenosis of the elephant trunk. Endovascular treatment for the stenotic elephant trunk was successfully performed. The postoperative course was uneventful, and the hemolysis was resolved immediately after operation.

  6. Comparison of Self-Expanding Polyethylene Terephthalate and Metallic Stents Implanted in Porcine Iliac Arteries

    International Nuclear Information System (INIS)

    Wilczek, Krzysztof; Scheerder, Ivan de; Wang Kai; Verbeken, Eric; Piessens, Jan

    1996-01-01

    Purpose: Comparison of the biocompatibility of self-expanding polyethylene terephthalate (PET) stents with self-expanding metallic stents (Wallstents). Methods: Diameter- and length-matched PET stents and Wallstents were symmetrically implanted in the paired iliac arteries of 13 crossbred domestic swine. Stent deployment was studied angiographically and with intravascular ultrasound immediately after stent implantation. The angiographic stented lumen diameter was measured using quantitative vessel analysis before, immediately after stenting, and at 6-week follow-up. Cross-section histopathology and area morphometry were performed. Results: Immediately poststenting, intravascular ultrasound revealed proximal dislocation of 5 of the 13 PET stents, whereas all metal stents were firmly embedded at the implantation site. At 6-week follow-up, three of the remaining PET stents were totally or subtotally occluded by organized thrombus, whereas all metal stents were patent. Compared with immediately poststenting, the angiographic lumen diameter within the five remaining PET stents was reduced by 30%, and that of the metallic stents was virtually unaltered (p < 0.02). This observation was confirmed by postmortem morphometry, wherein the PET-stented vessel segments a diameter stenosis of 40% was measured vs only 9% in the metallic stents (p < 0.0001). Conclusion: PET-stent deployment is difficult to control due to the lack of radiopacity of this stent. PET stents seem to be more thrombogenic and lead to significantly more neointimal proliferation than metallic stents

  7. Capítulo 15. Seguimiento al paciente con dispositivos de estimulación cardiaca

    Directory of Open Access Journals (Sweden)

    Clara I. Saldarriaga

    2016-03-01

    Conclusión: Los pacientes con cardiorresincronizador y desfibrilador implantable deben seguirse en clínicas de falla cardiaca para garantizar la adecuada selección de los candidatos y la optimización de la terapia.

  8. Intravascular Large B-Cell Lymphoma Presenting with Diffuse Gallbladder Wall Thickening: A Case Report and Literature Review

    Directory of Open Access Journals (Sweden)

    Sayf Al-Katib

    2018-01-01

    Full Text Available Intravascular large B-cell lymphoma is a rare subtype of extranodal diffuse B-cell lymphoma characterized by proliferation of neoplastic cells within the lumen of small and medium sized vessels. Clinical and imaging findings are nebulous as the intravascular subtype of lymphoma can involve a multitude of organs. Involvement of the gallbladder is extremely uncommon, and imaging findings can be easily confused for more prevalent pathologies. We report a case of intravascular large B-cell lymphoma in an 83-year-old male and review clinical presentation and imaging findings on CT, ultrasound, hepatobiliary iminodiacetic acid (HIDA scan, and MRI. It is important for the radiologist to know about this disease as the imaging findings are atypical of other types of lymphoma, and this may lead to a delay in diagnosis and treatment.

  9. Combined hyponatremia and hypocalcemia after intravascular absorption of 1.5% glycine during operative hysteroscopy. A case report

    Directory of Open Access Journals (Sweden)

    Sherif S. Sultan

    2016-07-01

    Full Text Available Intravascular absorption of distending media may complicate operative hysteroscopy. Consequences differ according to type, amount and speed of absorption of the distending media. We report a case of intravascular absorption of more than one liter of 1.5% glycine. A 36 years old female developed metabolic acidosis, hyponatremia and hypocalcemia during operative hysteroscopy scheduled for resection of a uterine fibroid. Serum sodium reached down to 119 mmol/l and ionized calcium to 0.898 mmol/l. Serial estimations of arterial blood gases and serum electrolytes were followed. Management was successful in preventing serious side effects. Meticulous monitoring of distending media input/output balance remains the cornerstone in prevention of intravascular absorption.

  10. Effects of Hypoxia on Erythrocyte Membrane Properties—Implications for Intravascular Hemolysis and Purinergic Control of Blood Flow

    Directory of Open Access Journals (Sweden)

    Ryszard Grygorczyk

    2017-12-01

    Full Text Available Intravascular hemolysis occurs in hereditary, acquired, and iatrogenic hemolytic conditions but it could be also a normal physiological process contributing to intercellular signaling. New evidence suggests that intravascular hemolysis and the associated release of adenosine triphosphate (ATP may be an important mechanism for in vivo local purinergic signaling and blood flow regulation during exercise and hypoxia. However, the mechanisms that modulate hypoxia-induced RBC membrane fragility remain unclear. Here, we provide an overview of the role of RBC ATP release in the regulation of vascular tone and prevailing assumptions on the putative release mechanisms. We show importance of intravascular hemolysis as a source of ATP for local purinergic regulation of blood flow and discuss processes that regulate membrane propensity to rupture under stress and hypoxia.

  11. Implementación de un laboratorio virtual para el estudio de dispositivos electrónicos

    Directory of Open Access Journals (Sweden)

    Ibarra B., Carlos Andrés

    2007-01-01

    Full Text Available El presente artículo presenta la implementación de un laboratorio virtual para que a través de Internet cumpla con objetivos pedagógicos en el estudio de los dispositivos electrónicos básicos usados en la enseñanza de la electrónica en las Universidades. Se desarrolla un sistema hardware, en el cuál se encuentran diversos montajes de los dispositivos electrónicos básicos y todo el sistema de selección, adecuación y adquisición de las señales de estos montajes. Para llevar a cabo este proceso, se ha utilizado un microcontrolador, el cual interactúa con el equipo servidor mediante un puerto serial y al que le permite transmitir la totalidad de los datos adquiridos de las señales de los dispositivos. La visualización de los datos al estudiante se realiza mediante gráficas en Java, montadas en el equipo servidor por medio de una página Web con manejo de bases de datos que permita el control de acceso y la interacción entre el estudiante usuario del laboratorio virtual y el docente encargado de éste. Esta página Web posee el enlace a los Applets y Servlets encargados de capturar los parámetros que serán entregados a la tarjeta microcontrolada y la interfaz para la visualización de los datos retornados.

  12. Offline fusion of co-registered intravascular ultrasound and frequency domain optical coherence tomography images for the analysis of human atherosclerotic plaques

    DEFF Research Database (Denmark)

    Räber, Lorenz; Heo, Jung Ho; Radu, Maria D

    2012-01-01

    To demonstrate the feasibility and potential usefulness of an offline fusion of matched optical coherence tomography (OCT) and intravascular ultrasound (IVUS)/virtual histology (IVUS-VH) images.......To demonstrate the feasibility and potential usefulness of an offline fusion of matched optical coherence tomography (OCT) and intravascular ultrasound (IVUS)/virtual histology (IVUS-VH) images....

  13. Comparison of utility of blood cultures from intravascular catheters and peripheral veins: a systematic review and decision analysis.

    Science.gov (United States)

    Falagas, Matthew E; Kazantzi, Maria S; Bliziotis, Ioannis A

    2008-01-01

    Blood cultures are sometimes obtained from intravascular catheters for convenience. However, there is controversy regarding this practice. The authors compared the diagnostic test characteristics of blood cultures obtained from intravascular catheters and peripheral veins. Relevant studies for inclusion in this review were identified through PubMed (January 1970-October 2005) and the Cochrane Central Register of Controlled Trials. Studies that reported clear definitions of true bacteraemia were included in the analysis. Two reviewers independently extracted the data. Six studies were included in the analysis, providing data for 2677 pairs of blood cultures obtained from an intravascular catheter and a peripheral venipuncture. A culture obtained from an intravascular catheter was found to be a diagnostic test for bacteraemia with better sensitivity (OR 1.85, 95 % CI 1.14-2.99, fixed effects model) and better negative predictive value (almost with statistical significance) (OR 1.55, 95 % CI 0.999-2.39, fixed effects model) but with less specificity (OR 0.33, 95 % CI 0.18-0.59, random effects model) and lower positive predictive value (OR 0.41, 95 % CI 0.23-0.76, random effects model) compared to a culture taken by peripheral venipuncture. In a group of 1000 patients, eight additional patients with true bacteraemia would be identified and 59 falsely diagnosed as having bacteraemia by a blood culture obtained from an intravascular catheter compared to results of the peripheral blood culture. Given the consequences of undertreating patients with bacteraemia, the authors believe that, based on the available evidence, at least one blood culture should be obtained from the intravascular catheter.

  14. La “Gran Soriano”: el periodismo como sostén de un dispositivo mitográfico

    Directory of Open Access Journals (Sweden)

    Rogelio Demarchi

    2016-09-01

    Full Text Available Osvaldo Soriano (1943-1997 publicó cuatro libros de crónicas sobre la base de su producción periodística. Lo más significativo de ellos es que utiliza pequeños textos introductorios como sostén de un dispositivo mitográfico que abarca su trayectoria y sus vivencias. En consecuencia, se puede leer al Soriano-periodista y al Soriano-personaje como construcciones ficcionales del Soriano-autor.

  15. Fiabilidad intra-participante de diferentes modelos de dispositivos GPS implementados en un partido de Fútbol 7

    Directory of Open Access Journals (Sweden)

    Julen Castellano

    2010-01-01

    Full Text Available El objetivo de este estudio fue estimar la fiabilidad intra-participante de tres modelos de GPS (Global Positioning System MinimaxX (Catapult Innovations, Australia, SPI10 y WiSpi (GPSports, Australia que operan a una frecuencia de 5,1 y 1 Hz, respectivamente. Se midieron distancias recorridas a distintas intensidades a 5 jugadores de fútbol (edad, 20,1 ± 1,2 años; altura, 176,3 ± 9,9 cm; peso, 63,5 ± 8,4 kg en un partido de entrenamiento de 33 min, en un campo de fútbol-7 (6 jugadores de campo y 1 portero. La distancia total recorrida (DT media fue de 3.288,8 m para los modelos MinimaxX, 3.050,3 m para el WiSPI y de 3.247,5 m para el SPI10. La velocidad máxima obtenida por cada modelo fue de 30.3 km·h-1 en los dispositivos MinimaxX, y de 25,1 y de 25.2 km·h-1 en los dispositivos WiSPI y SPI10, respectivamente. Se estimó el coeficiente de variación (CV entre los 3 modelos estudiados para la distancia recorrida en cada uno de los 4 niveles de velocidad, así como para la distancia total recorrida, y la velocidad media y máxima, siendo el tamaño de la muestra la principal limitación. En base a los resultados podemos concluir que los diferentes dispositivos presentan una alta fiabilidad para medir la distancia total recorrida y las recorridas en categorías de baja velocidad. Sin embargo la velocidad de los desplazamientos realizados durante el partido condiciona la fiabilidad de los diferentes dispositivos, aumentando la dispersión de las medidas obtenidas (CV a medida que se incrementa la velocidad de carrera; especialmente cuando se supera la velocidad de 13 km·h-1.

  16. Sistematización del diseño de dispositivos de levitación superconductora por efecto Meissner

    OpenAIRE

    Díaz García, José Alberto

    2011-01-01

    Esta tesis doctoral aporta un esquema sistemático para el diseño de dispositivos de levitación magnética superconductora por efecto Meissner. Partiendo de la expresión propuesta recientemente por Pérez-Díaz y García-Prada (PDGP) en este trabajo se demuestra que la aplicabilidad de dicha expresión es general y se deriva de las ecuaciones de Maxwell y London. Esta expresión, aunque deducida en el caso de exclusión total de campo magnético o estado Meissner, permite también tratar...

  17. Sistematización del diseño de dispositivos de levitación superconductora por efecto Meissner

    OpenAIRE

    Díaz García, José Alberto

    2008-01-01

    Esta tesis doctoral aporta un esquema sistemático para el diseño de dispositivos de levitación magnética superconductora por efecto Meissner. Partiendo de la expresión propuesta recientemente por Pérez-Díaz y García-Prada (PDGP) en este trabajo se demuestra que la aplicabilidad de dicha expresión es general y se deriva de las ecuaciones de Maxwell y London. Esta expresión, aunque deducida en el caso de exclusión total de campo magnético o estado Meissner, permite también tratar...

  18. Técnicas anti-forenses para vídeos de dispositivos móviles

    OpenAIRE

    Quinto Huamán, Carlos

    2016-01-01

    En los últimos años el número de teléfonos móviles ha crecido notablemente. Producto de este impacto, los usuarios pasan gran parte de su tiempo sumergidos en este dispositivo. La cámara digital integrada en un teléfono inteligente es un componente usado frecuentemente para capturar gran cantidad de imágenes y vídeos de acontecimientos de la vida cotidiana de una persona. Esto permite dejar evidencia de situaciones que pueden comprometer la presunción de inocencia de las personas en actos que...

  19. Um framework de conceitos autonômicos para o controle de testes de dispositivos móveis

    OpenAIRE

    LINO, Nancy de Lyra

    2009-01-01

    Diante do dinamismo do mercado de telefonia, fabricantes de dispositivos móveis junto com operadoras vêm buscando acelerar o processo de entrada de novas tecnologias que possibilitem ao usuário final explorar o melhor uso da infra-estrutura. Até bem pouco tempo atrás, um telefone celular tinha como propósito fim a realização apenas de chamadas de voz. Hoje, direcionado pela convergência digital, o próprio mercado visa à miniaturização e uma gama sem fim de novos serviços que po...

  20. Revisión de opciones para el uso de la plataforma Moodle en dispositivos Móviles

    OpenAIRE

    Arjona Heredia, José Emilio; Gámiz Sánchez, Vanesa

    2015-01-01

    Los espacios y modelos de aprendizaje se han visto modificados radicalmente en los últimos tiempos gracias al avance de las tecnologías de la comunicación que han hecho posible el acceso y la producción de grandes cantidades de información; el desarrollo de aplicaciones y herramientas para mejorar la interacción entre las personas; y la extensión de dispositivos que han permitido el aumento de la movilidad de los usuarios. En este artículo se analizan cuáles son las circunstancias que están p...

  1. Revisión de opciones para el uso de la plataforma Moodle en dispositivos Móviles

    OpenAIRE

    José Emilio Arjona Heredia; Vanesa Mª Gámiz Sánchez

    2013-01-01

    Los espacios y modelos de aprendizaje se han visto modificados radicalmente en los últimos tiempos gracias al avance de las tecnologías de la comunicación que han hecho posible el acceso y la producción de grandes cantidades de información; el desarrollo de aplicaciones y herramientas para mejorar la interacción entre las personas; y la extensión de dispositivos que han permitido el aumento de la movilidad de los usuarios. En este artículo se analizan cuáles son las circunstancias que están p...

  2. Repensando el dispositivo de retroalimentación sobre la planificación de las prácticas

    OpenAIRE

    Giovannini, Marianela I.; Savransky, Natalí L.

    2015-01-01

    El presente trabajo aborda uno de los problemas emergentes en la formación docente inicial de abogados en el marco de la asignatura “Residencia Docente” del Profesorado en Ciencias Jurídicas de la Facultad de Derecho de la Universidad de Buenos Aires. La experiencia que presentaremos guarda estrecha relación con el trabajo realizado en los últimos dos años en la cátedra, en relación con el dispositivo de retroalimentación de las planificaciones de los alumnos para sus prácticas en el nivel se...

  3. Implementación de un sistema de adaptación y reconocimiento de locutor en un dispositivo portable

    OpenAIRE

    Díez Sánchez, César

    2010-01-01

    En el presente documento se describe un proyecto que se encuentra situado dentro del marco de las Tecnologías del Habla. En el mismo, se desarrollan varios módulos que se integran en el sistema de Verificación de Locutor independiente de texto diseñado para dispositivos portátiles del tipo PDA. En la primera parte de este proyecto se han centrado todos los esfuerzos en conocer la descripción de este tipo de aplicaciones. Para ello, en el presente documento se detalla cada uno de los bloques d...

  4. Limitaciones de las actuales herramientas de análisis digital forense para dispositivos móviles

    OpenAIRE

    Amsler, G. A.; Casco, María Eugenia; Roatta, Santiago

    2017-01-01

    Este informe describe la resolución de un problema de ingeniería de la asignatura Seguridad Informática de la Carrera de Ingeniería en Sistemas de la Universidad Abierta Interamericana. El objetivo del trabajo fue realizar una comparación cualitativa y cuantitativa de diferentes herramientas de adquisición de evidencia digital en dispositivos móviles. Las tareas se desarrollaron en el marco de una pasantía de un año realizada en el Laboratorio de Análisis Digital Forense de la Policía de Inve...

  5. Dispositivos de tecnología de asistencia para alimentación = Devices of assistive technology for feeding

    Directory of Open Access Journals (Sweden)

    Losada Gómez, A

    2007-02-01

    Full Text Available RESUMENEste artículo presenta los principales dispositivos de tecnología de asistencia que existen en Bogotá para facilitar el desempeño de la actividad de alimentación en personas que presentan algún tipo de discapacidad que limite esta ejecución, para ello, fue necesario realizar un estudio descriptivo donde se aplicó un instrumento tipo encuesta a personas que comercializan los mismos. Los principales resultados determinan que existen diferentes dispositivos para la función motora (mantener la postura sedente, facilitar agarres, facilitar patrón mano-boca y los patrones bucales (succión, deglución, masticación y digestión que se requieren en la alimentación. Como conclusión se determinó que actualmente en Colombia, los dispositivos de tecnología de asistencia para la alimentación son de baja tecnología y que existe fácil acceso a los mismos, pero se requiere realizar mayor difusión, también se encontró que no existen dispositivos que puedan facilitar esta actividad a personas que presenten parálisis en miembros superiores y que son mínimos los que presentan aplicación de tecnología de puntaABSTRACTThis article presents the principal devices of assistive technology that exist in Bogotá to facilitate the development of the activity of feeding in people that present some type of disability that limits this execution. Therefore, it was necessary to develop a descriptive study that included an instrument kind of inquiry to people that commercialize this devices. The principal results determine that there are different devices for the motor function (keep the sedentary posture, facilitate grips, facilitate hand-mouth patron and the buccal patrons (sucking, swallowing, chewing and digestion that are required in the feeding. As a conclusion it was determined that at present in Colombia, the devices of assistive technology for feeding have a low level of technology and there is an easy access to them, but is required to

  6. Método de identificación de huellas dactilares y dispositivo que hace uso del mismo

    OpenAIRE

    Arjona, Rosario; Baturone, I.

    2013-01-01

    Se describen en este documento un método y un dispositivo que permiten generar un vector de características de una huella dactilar humana mediante una serie de procesos realizados a partir de la imagen de dicha huella. Con esos vectores se puede realizar una clasificación, indexación o determinación de identidad de huellas (y, por tanto, de individuos), así como proteger secretos o generar claves criptográficas a partir de huellas. La mayoría de los métodos de identificación reportados em...

  7. Retrograde peri-implantitis

    Directory of Open Access Journals (Sweden)

    Mohamed Jumshad

    2010-01-01

    Full Text Available Retrograde peri-implantitis constitutes an important cause for implant failure. Retrograde peri-implantitis may sometimes prove difficult to identify and hence institution of early treatment may not be possible. This paper presents a report of four cases of (the implant placed developing to retrograde peri-implantitis. Three of these implants were successfully restored to their fully functional state while one was lost due to extensive damage. The paper highlights the importance of recognizing the etiopathogenic mechanisms, preoperative assessment, and a strong postoperative maintenance protocol to avoid retrograde peri-implant inflammation.

  8. Combined hyponatremia and hypocalcemia after intravascular absorption of 1.5% glycine during operative hysteroscopy. A case report

    OpenAIRE

    Sherif S. Sultan

    2016-01-01

    Intravascular absorption of distending media may complicate operative hysteroscopy. Consequences differ according to type, amount and speed of absorption of the distending media. We report a case of intravascular absorption of more than one liter of 1.5% glycine. A 36 years old female developed metabolic acidosis, hyponatremia and hypocalcemia during operative hysteroscopy scheduled for resection of a uterine fibroid. Serum sodium reached down to 119 mmol/l and ionized calcium to 0.898 mmol/l...

  9. Individual titanium zygomatic implant

    Science.gov (United States)

    Nekhoroshev, M. V.; Ryabov, K. N.; Avdeev, E. V.

    2018-03-01

    Custom individual implants for the reconstruction of craniofacial defects have gained importance due to better qualitative characteristics over their generic counterparts – plates, which should be bent according to patient needs. The Additive Manufacturing of individual implants allows reducing cost and improving quality of implants. In this paper, the authors describe design of zygomatic implant models based on computed tomography (CT) data. The fabrication of the implants will be carried out with 3D printing by selective laser melting machine SLM 280HL.

  10. Development of sup 1 sup 9 sup 2 Ir radiation sources for intravascular irradiation

    CERN Document Server

    Kogure, H; Iwamoto, S; Iwata, K; Kawauchi, Y; Nagata, Y; Sorita, T; Suzuki, K

    2003-01-01

    Intravascular brachytherapy is a novel therapy for preventing the restenosis of coronary artery by use of low-dose irradiation. JAERI and Kyoto University have been developing sup 1 sup 9 sup 2 Ir radiation sources by the cooperative research project entitled as 'The research on safety and effectiveness of the intravascular brachytherapy for preventing restenosis of the coronary artery disease' since 1998. The radiation source was introduced into the stenosis through a catheter (a guide-tube to insert directly into vascular) to irradiate the diseased part. Ten sup 1 sup 9 sup 2 Ir seed sources (phi 0.4 mm x 2.5 mm) were positioned between nylon spacers (phi 0.3 mm x 1.0 mm) in a flexible covering tube and the tube was plugged with a core-wire; the tube was shrunk to fix the inside materials and the size is 0.46 mm in diameter and 3 m in length. The physically optimal design was determined to insert the radiation source easily into vascular and to get the dose uniformity in the diseased part. The production me...

  11. Intrauterine intravascular transfusion for fetal haemolytic anaemia: the Western Australian experience.

    Science.gov (United States)

    Newnham, J P; Phillips, J M; Stock, R

    1992-11-16

    To report the first four years' clinical experience with fetal intravascular blood transfusion for the treatment of fetal haemolytic anaemia in Western Australia. King Edward Memorial Hospital, Perth, which is the sole tertiary level perinatal centre in Western Australia with a referral base of approximately 25,000 pregnancies each year. Transfusion was by injection of packed cells from Rh-negative donors into the fetal umbilical vein near the site of insertion into the placenta. Fetal haemoglobin levels were measured before and after each transfusion. In most cases, the fetus was paralysed by intramuscular tubocurarine. Sixty intravenous transfusions were performed in 20 pregnancies. At the time of the initial transfusion, the mean haemoglobin level was 5.8 g/dL (range, 2.5-8.5 g/dL) and six fetuses had signs of hydrops. The case survival rate was 80% and the procedure survival rate was 93%. Three of the deaths occurred in the first five cases. Caesarean section was performed during two of the procedures, one because of bleeding from the cord puncture site and one because of tamponade of the umbilical vessels. Fetal intravascular transfusion is a highly effective treatment for fetal alloimmunisation and allows pregnancies to continue to term and to be delivered vaginally. However, the procedure may be difficult and requires a team approach with ready access to fetal monitoring and emergency caesarean section. Our results suggest that increasing experience of the team is a major factor in improved outcome.

  12. Pulmonary intravascular lymphoma detected by FDG PET-CT: a case report.

    Science.gov (United States)

    Kohan, A A; Paganini, L; Biedak, P; Arma, J I; Dalurzo, M C L; Garcia-Monaco, R D

    2013-01-01

    Intravascular lymphoma is a rare subtype of extranodal Non-Hodgkin's lymphoma. Its prognosis is poor in a high percentage of cases due to its insidious appearance and low clinical suspicion. Its diagnosis is usually only reached after an autopsy. It may affect different organs as a whole or only one organ. It is extremely rare that the lung is the only damaged organ. Its diagnosis depends of the clinician's suspicion and proper evaluation with imaging studies as well as correct selection of the organ to be biopsied. When detected on time, the treatment of choice is a combination of a series of chemotherapy associated to a monoclonal antibody (anti-CD20). We present the case of a male patient who underwent a positron emission tomography-computed tomography with 2-[F-18]-fluoro-2 deoxy-D-glucose (FDG) due to symptoms suggestive of a lymphoproliferative disease with no clear structural abnormalities. The images led to a diagnosis of pulmonary intravascular large B cell lymphoma. Copyright © 2012 Elsevier España, S.L. and SEMNIM. All rights reserved.

  13. Plasma volume, intravascular albumin and its transcapillary escape rate in patients with extensive skin disease

    DEFF Research Database (Denmark)

    Parving, H H; Worm, A M; Rossing, N

    1976-01-01

    Plasma volume and plasma concentration and transcapillary escape rate of albumin (TER alb), i.e. the fraction of intravascular mass of albumin that passes to the extravascular space per unit time, were determined using 125I-labelled human albumin in eight patients with extensive skin disease....... Plasma volume and plasma albumin concentration were reduced (P less than 0-05). Thus the intravascular albumin mass was moderately decreased to an average of 0-55 +/- 0-06 (s.d.) g/cm height compared with a normal mean value of 0-77 +/- 0-07 (s.d.) g/cm. This 29% decrease is statistically significant (P...... less than 0-001). The transcapillary escape rate of albumin (TER alb) was significantly elevated, mean 8-6 +/- 1-1 (s.d.) % X h-1, as compared to normal subjects, mean 5-6 +/- 1-1 (s.d.) % X h-1, (+54%, P less than 0-001). The same patients were studied again after a 1-week treatment with prednisone...

  14. Focus on the research utility of intravascular ultrasound - comparison with other invasive modalities

    Directory of Open Access Journals (Sweden)

    Hoye Angela

    2011-01-01

    Full Text Available Abstract Intravascular ultrasound (IVUS is an invasive modality which provides cross-sectional images of a coronary artery. In these images both the lumen and outer vessel wall can be identified and accurate estimations of their dimensions and of the plaque burden can be obtained. In addition, further processing of the IVUS backscatter signal helps in the characterization of the type of the plaque and thus it has been used to study the natural history of the atherosclerotic evolution. On the other hand its indigenous limitations do not allow IVUS to assess accurately stent struts coverage, existence of thrombus or exact site of plaque rupture and to identify some of the features associated with increased plaque vulnerability. In order this information to be obtained, other modalities such as optical coherence tomography, angioscopy, near infrared spectroscopy and intravascular magnetic resonance imaging have either been utilized or are under evaluation. The aim of this review article is to present the current utilities of IVUS in research and to discuss its advantages and disadvantages over the other imaging techniques.

  15. Cardiac variation of inferior vena cava: new concept in the evaluation of intravascular blood volume.

    Science.gov (United States)

    Nakamura, Kensuke; Tomida, Makoto; Ando, Takehiro; Sen, Kon; Inokuchi, Ryota; Kobayashi, Etsuko; Nakajima, Susumu; Sakuma, Ichiro; Yahagi, Naoki

    2013-07-01

    Evaluation of the intravascular blood volume is an important assessment in emergency and critical care medicine. Measurement of the inferior vena cava (IVC) respiratory variation by ultrasound echography is useful, but it entails subjective problems. We have hypothesized that IVC cardiac variation is also correlated with intravascular blood volume and analyzed it automatically using computer software of two kinds, later comparing the results. Snakes, software to track boundaries by curve line continuity, and template matching software were incorporated into a computer with an ultrasound machine to track the short-axis view of IVC automatically and analyze it with approximation by ellipse. Eight healthy volunteers with temporary mild hypovolemia underwent echography before and after passive leg raising and while wearing medical anti-shock trousers. IVC cardiac variation was visually decreased by both leg raising and medical anti-shock trousers. The collapse index (maximum - minimum/maximum) of area during three cardiac beats was decreased showing a good relationship to fluid load simulations; 0.24 ± 0.03 at baseline versus 0.11 ± 0.01 with leg raising and 0.12 ± 0.01 with medical anti-shock trousers. In conclusion, IVC cardiac variation has the potential to provide an evaluation of water volume. It presents some advantages in mechanical analysis over respiratory variation. At the very least, we need to exercise some caution with cardiac variation when evaluating respiratory variation.

  16. One-stage surgery for removal of intravascular leiomyomatosis extending to right ventricle.

    Science.gov (United States)

    Chiang, Ching-Shu; Chen, Po-Lin; Kuo, Tzu-Ting; Chen, I-Ming; Wu, Nai-Yuan; Chang, Hsiao-Huang

    2018-03-01

    Intravascular leiomyomatosis (IVL) is a rare nonmalignant tumor that can be fatal if untreated. A 49-year-old nulliparous Asian woman who underwent hysterectomy and left salpingo-oophorectomy for multiple uterine leiomyomas 18 months prior presented complaining of intermittent palpitation and chest tightness for approximately 1 month. Echocardiography revealed a large mobile tumor mass extending from the inferior vena cava (IVC) to the right atrium that partially obstructed IVC flow and tricuspid inflow. Thoracicabdominopelvic computed tomography revealed a left adnexal tumor (4.8 × 2.5 cm) causing intravascular obstruction extending from the left internal iliac vein to the IVC, right atrium, and right ventricle. IVL with right heart involvement INTERVENTIONS:: Under cardiopulmonary bypass, a one-stage surgery combining sternotomy and laparotomy was performed. The tumor was approached and extracted via sternotomy, and tumor detachment and removal of residual tumors was accomplished via laparotomy. A firm, smooth, and regularly shape tumor 15.5 × 5.5 × 2.5 in size was completely removed and histopathologically confirmed as IVL. The patient tolerated the surgical procedure well and no postoperative complication was noted. We describe a one-stage surgical approach to completely remove an IVL extending to the right ventricle.

  17. Visualization of Chronic Myocardial Infarction Using the Intravascular Contrast Agent MS-325 (Gadofosveset in Patients

    Directory of Open Access Journals (Sweden)

    Thomas Thouet

    2012-01-01

    Full Text Available Aims. The aim of this study was to evaluate the potential of visualizing chronic myocardial infarction in patients using the intravascular CA MS-325 (gadofosveset, EPIX Pharmaceuticals, Mass, USA. Methods. Nine patients were enrolled in a clinical phase II multicenter trial for MRCA and perfusion imaging using MS-325. They had objective evidence of chronic myocardial infarction as visualized by previously performed late gadolinium (Gd enhancement imaging (LGE with a conventional extracellular Gd-DTPA CA (Magnevist, Bayer Healthcare, Germany, 0.2 mmol/kg/body weight serving as reference standard. A prepulse-optimized LGE study was performed immediately and at several time points after injection of MS-325 (0.05 mmol/kg/body weight. The number and localization of segments demonstrating LGE with MS-325 as well as signal intensities were compared with the reference standard (Gd-DTPA. Results. Using MS-325, LGE could be detected at every time point in all 9 patients. The accuracy of LGE with MS-325 as compared to LGE with Gd-DTPA was highest 54±4 minutes after contrast injection, resulting in a sensitivity of 84% with a specificity of 98%. Conclusion. The intravascular CA MS-325 has the potential to visualize chronic myocardial infarction. However, in comparison with Gd-DTPA, the transmural extent and the number of segments are smaller.

  18. Dispositivos de transformação do sofrimento em adoecimento numa empresa Dispositivos de transformación del sufrimiento en padecimiento em una empresa Transformation devices from suffering to illness within a service firm

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Brant

    2007-12-01

    Full Text Available O dispositivo como mecanismo institucional alcança nova ordem e disposição para atingir um fim. Identificamos instrumentos transformadores do sofrimento em adoecimento. Entrevistamos trabalhadores, gestores e profissionais da saúde do setor de serviços, em Belo Horizonte. O mascaramento do sofrimento, a sustentação e regulação da morbidade e a construção da identidade de doente constituíram alguns dispositivos. Esses mecanismos articulavam-se com o desenvolvimento das neurociências. O sentido clássico da cura é substituído pela psiquiatrização, através de uma interpretação individualizante e medicalização abusiva. Concluiu-se que esses instrumentos inseriam-se na transição das "sociedades disciplinares" para as "de controle". Os dispositivos utilizados na gestão do trabalho, embora permitissem avanços profissionais, agudizavam o controle sobre o corpo, o domínio dos espaços da vida privada e a culpabilização dos trabalhadores pelo processo saúde-doença-cuidado, favorecendo a transformação do sofrimento em adoecimento.A partir del entendimiento del dispositivo como mecanismo institucional para alcanzar un fin, identificamos varios instrumentos transformadores del sufrimiento en padecimiento. Entrevistamos trabajadores, gestores e profesionales de salud de una empresa del sector de servicios de Belo Horizonte. El enmascaramiento del sufrimiento, la sustentación y regulación de la morbilidad y la construcción de la identidad de enfermo constituyeron algunos de los dispositivos, que están en consonancia con el desarrollo de las neurociencias. El sentido clásico da curación es substituido por la psiquiatrización, a través de una interpretación individualizante y de medicalización abusiva. Concluyese que esos instrumentos hacen parte de la transición de las "sociedades disciplinares" para las "de control". A pesar de que permiten avances profesionales, agudizan el control sobre el cuerpo, la dominación de

  19. Dispositivo de assistência circulatória mecânica intraventricular de fluxo axial: estudo in vitro In vitro evaluation of an intraventricular axial flow pump for mechanical circulatory support

    Directory of Open Access Journals (Sweden)

    Luiz Fernando KUBRUSLY

    2000-06-01

    Full Text Available É apresentado estudo in vitro de um dispositivo de assistência circulatória totalmente implantável no ventrículo esquerdo, de fluxo axial e de tamanho pequeno (30 cc - 7 cm comprimento. Apesar dessas características foi capaz de gerar fluxos entre 5 - 8 l/min com motor, operando em 8 W, sem causar hemólise em período de até 12 horas. O custo de produção, excetuando-se o sistema de baterias, foi projetado entre 5 - 8 mil dólares, o que o torna viável para utilização clínica rotineira em nosso país.We are currently studying an intraventricular axial flow blood pump in vitro. It is designed for long term left ventricular support. The small (30 cc, 7 cm length was capable of producing flows of 5 - 8 l/min on a 8 W motor, with no device related hemolysis throughout the 12 h of the study. The cost of production, except for the batteries, has been estimated at between 5 - 8 thousand dollars, a reasonable amount for routine clinical use in Brazil.

  20. Estudo experimental da aplicação do ventrículo artificial eletromecânico pulsátil implantável Experimental study of pulsatile implantable electromechanical artificial ventricle

    Directory of Open Access Journals (Sweden)

    Jarbas Jakson Dinkhuysen

    2011-03-01

    Full Text Available OBJETIVO: Apresentar os resultados da aplicação deste dispositivo em animais de experimentação, promovendo auxílio hemodinâmico apenas ao ventrículo esquerdo (VE. MÉTODOS: Entre junho 2002 e outubro 2009, foram implantados em 27 bezerros com idade 2½ a 4 meses e peso 80/100 kg e, por meio de anestesia geral e ventilação controlada e de toracotomia lateral esquerda, era introduzida cânula no ápice do VE e anastomose término/lateral de tubo vascular de politetrafluoretileno (PTFE com a porção descendente da aorta torácica, ambos interligados ao dispositivo implantado no subcutâneo abaixo do diafragma (24 e intratorácico (três. Em cinco bezerros, o dispositivo foi aplicado com auxílio de circulação extracorpórea (CEC e, em 22, sem CEC. RESULTADOS: Ocorreram dois óbitos durante o implante e três por causas diversas nas primeiras horas de pós-operatório (PO, sendo um relacionado ao dispositivo. A sobrevivência entre o 1º e 6º dia de PO ocorreu em 17 animais e entre o 8º e 31º dia de PO em cinco, com causas determinantes diversas, não só por problemas clínico/cirúrgicos, mas também relacionados ao dispositivo. O impacto hemodinâmico avaliado pela análise da pressão sistêmica mostrou incremento que variou de 20 a 40 mmHg e os dados laboratoriais analisados demonstraram baixos impactos traumáticos à crase sanguínea e boa biocompatibilidade. CONCLUSÃO: Trata-se de pesquisa árdua e complexa onde a cada experimento são identificados problemas não só de implantabilidade, mas também relacionados ao dispositivo, que vão sendo sistematicamente corrigidos, tornando-o cada vez mais seguro e eficaz.OBJECTIVE: The objective is to present the results of the application this device in experimental animals unloading only the left ventricle. METHODS: Between June 2002 and October 2009, were implanted in 27 calfs with age between 2½ to 4 months and 80 to 100 kg of weight, with general anaesthesia and controled

  1. Aplicación móvil para dispositivos Apple® que utiliza elementos visuales para interactuar con una vivienda inteligente. Control de persiana

    OpenAIRE

    Grupo de Domótica y Ambientes Inteligentes

    2014-01-01

    En los vídeos se muestra una aplicación móvil para dispositivos Apple® que utiliza elementos visuales para interactuar con una vivienda inteligente. La interfaz consiste en una representación de la vivienda real en 3D a través de la cual se puede controlar de manera intuitiva la iluminación, clima, persianas, TV, etc. En concreto, la interfaz permite interactuar con los dispositivos reales de la vivienda tocando su representación virtual en la interfaz. Debido a la sencillez en el uso de la m...

  2. Aplicación móvil para dispositivos Apple® que utiliza elementos visuales para interactuar con una vivienda inteligente. Control de panel luminoso

    OpenAIRE

    Grupo de Domótica y Ambientes Inteligentes

    2014-01-01

    En los vídeos se muestra una aplicación móvil para dispositivos Apple® que utiliza elementos visuales para interactuar con una vivienda inteligente. La interfaz consiste en una representación de la vivienda real en 3D a través de la cual se puede controlar de manera intuitiva la iluminación, clima, persianas, TV, etc. En concreto, la interfaz permite interactuar con los dispositivos reales de la vivienda tocando su representación virtual en la interfaz. Debido a la sencillez en el uso de la m...

  3. Integración de un sistema de televigilancia a través de de un dispositivo móvil en un servidor web

    OpenAIRE

    Galán García, Juan

    2009-01-01

    El Proyecto Fin de Carrera analiza e implementa un servidor Web de apoyo a un sistema de televigilancia instalado en un dispositivo móvil. Las funciones principales que implementa este sistema son: conexión del dispositivo móvil al servidor Web, almacenamiento de imágenes enviadas desde el teléfono móvil en un servidor Web y la visualización de las mismas en un navegador Web. Como última funcionalidad el servidor Web generará un correo electrónico con la imagen recibida en el servidor. ...

  4. Diseño, Desarrollo y Validación de Dispositivo Robótico para la Supresión del Temblor Patológico

    OpenAIRE

    Rocon, E.; Ruíz, A.F.; Belda-Lois, J.M.; Moreno, J.C.; Pons, J.L.; Raya, R.; Ceres, R.

    2008-01-01

    Resumen: El uso de robots para la asistencia a personas ha sido considerado por muchos investigadores desde el comienzo de la robótica moderna. Hay muchos factores que están contribuyendo a expandir la necesidad de tales dispositivos, tales como el envejecimiento de la población en muchos países desarrollados y las expectativas generadas para una asistencia médica adecuada a personas discapacitadas. Este artículo describe la implementación de un dispositivo robótico en forma de exoesqueleto p...

  5. Diseño y evaluación funcional de un dispositivo médico para la fijación de mallas mediante adhesivo

    OpenAIRE

    Rosales Parral, Ivan

    2015-01-01

    Este proyecto esta englobado dentro de las actividades de optimización del diseño del dispositivo médico conocido con el nombre comercial de “Histoacryl® Applicator – Open Hernia Repair” e incluido dentro del pack “Histoacryl® Pro-Set OFX”, propiedad de B. Braun Surgical, S.A. y protegido por la patente WO 2013144849 A1. Este dispositivo ha sido creado para mejorar el método de aplicación del Histoacryl®, un adhesivo quirúrgico de uso interno con formulación n-butil-2-cianoacrilato. El dispos...

  6. Mapa y Cédula Escolar como dispositivos de planificación y gestión de políticas públicas educativas

    OpenAIRE

    Ghea, María Elisa

    2010-01-01

    "Mapa y Cédula Escolar como dispositivos de Planificación y Gestión de políticas públicas educativas", es un trabajo de tesis que propone abordar la conformación de sociedades de la información mediante la selección y análisis de determinadas herramientas informativas particulares como Mapa y Cédula Escolar, dos dispositivos comunicacionales de estadística y relevamiento de datos, elaborados en el año 2000 para conocer, comprender y planificar las políticas en el sistema educativo de la provi...

  7. Dispositivos móviles y el fenómeno del BYOD : Su impacto en la seguridad de las organizaciones

    OpenAIRE

    Venosa, Paula; Macia, Nicolás; Piazza Orlando, Carlos Damián; Pacheco Veliz, Sebastián Exequiel

    2016-01-01

    Las amenazas que atentan contra la seguridad de los dispositivos móviles: malware, robo, fuga de información, vulnerabilidades de software y phishing entre otras ponen en riesgo la seguridad personal de los usuarios y de los activos de información de las organizaciones en las que estos trabajan. Este artículo trata sobre el impacto del uso de los dispositivos móviles personales en las organizaciones lo cual se conoce como: Bring Your Own Device (BYOD). Este fenómeno constituye un campo de ...

  8. Estudio y análisis de seguridad en dispositivos móviles : BYOD y su impacto en las organizaciones

    OpenAIRE

    Pacheco Veliz, Sebastián Exequiel; Piazza Orlando, Carlos Damián

    2016-01-01

    Las amenazas que atentan contra la seguridad de los dispositivos móviles: malware, robo, fuga de información, vulnerabilidades de software y phishing entre otras ponen en riesgo la seguridad personal de los usuarios y de los activos de información de las organizaciones en las que estos trabajan. Esta tesis trata sobre el impacto del uso de los dispositivos móviles personales en las organizaciones lo cual se conoce como: Bring Your Own Device (BYOD). Este fenómeno constituye un campo de in...

  9. Red de nodos sensores y actuadores para control y supervisión de consumo de energía en dispositivos electrodomésticos

    OpenAIRE

    Peretti, Gastón; Gallina, Sergio Hilario; Felissia, Sergio Francisco; Villagrán, Luis Daniel; Beltramini, Paola; Herrera, Martín

    2013-01-01

    En la actualidad existen una gran variedad de sistemas domóticos que utilizan distintos protocolos para controlar los dispositivos hogareños, pero no existen desarrollos que integren la medición de energía en tiempo real de cada dispositivo y el control sobre los mismos al mismo tiempo. El presente proyecto pretende desarrollar una red de nodos sensores y actuadores configurables en tiempo real, que permitan implementar funciones de control y supervisión de consumo energético de artefactos y ...

  10. DISPOSITIVO DE MORALIZAÇÃO LAICA E SINTOMA SOCIAL DOMINANTE (Um Estudo da Educação Moral em Émile Durkheim

    Directory of Open Access Journals (Sweden)

    Heloisa Rodrigues Fernandes

    1990-12-01

    Full Text Available Defensores da educação laica e da educação religiosa têm marcado suas diferenças quanto à moralização infantil através dos efeitos que atribuem aos conteúdos da educação. O dispositivo de moralização laica do qual o discurso durkheirniano é sintoma permite formular a hipótese de que a relação entre os dois dispositivos pedagógicos pode ser de complementaridade e não de oposição.

  11. Arqueología Virtual en Dispositivos Móviles. Un Caso Práctico: Patrimonio Defensivo Medieval.

    Directory of Open Access Journals (Sweden)

    José M. Noguera

    2012-11-01

    Full Text Available La arqueología virtual es un interesante canal de promoción del patrimonio con fines turísticos. En este trabajo proponemos aplicar técnicas de realidad virtual en dispositivos móviles a fin de aprovechar las ventajas únicas que brindan dichas plataformas: ubiquidad y localización. Primeramente, describimos una arquitectura cliente-servidor capaz de proporcionar mapas 3D realistas en dispositivos móviles en función de la localización del usuario. A continuación, describimos un caso de estudio que consiste en aplicar dicha arquitectura para implementar una guía turística en 3D. El objetivo de esta guía es divulgar y promocionar la organización territorial y las edificaciones defensivas existentes en el “Concejo de Baeza” (España durante la baja Edad Media. Si bien, la guía se puede extrapolar fácilmente a otros periodos y áreas geográficas.

  12. PROPENSÃO DOS CONSUMIDORES AO USO DE SERVIÇOS DE PAGAMENTO EM DISPOSITIVOS MÓVEIS

    Directory of Open Access Journals (Sweden)

    Luis Hernan Contreras Pinochet

    2017-09-01

    Full Text Available O objetivo deste artigo é analisar a propensão do consumidor ao uso de serviços de pagamentos em dispositivos móveis a partir dos construtos: confiança, facilidade de uso percebida, utilidade percebida, inovação pessoal e autoeficácia. O modelo adaptado a este estudo foi proposto por Duane, O’ Reilly, e Andreev (2014. A pesquisa utilizou abordagem quantitativa com o apoio da técnica de coleta de dados do tipo survey em corte transversal único, obteve-se os dados oriundos de 365 respondentes que foram analisados por meio da técnica de Modelagem de Equações Estruturais – MEE. Os resultados obtidos demonstraram que todas as hipóteses foram validadas no modelo. O construto autoeficácia, que apesar de influenciar a propensão ao uso de pagamento em dispositivos móveis, apresentou menor carga, dado que a maior parte dos participantes,  por pertencerem a grupos de jovens usuários, caracterizam-se por viverem numa “nowconomy”, isto é, a busca pelo imediatismo, reduzindo assim, o tempo de utilização das novas tecnologias.

  13. Algoritmo para geolocalización de dispositivos móviles a partir de emisores de WIFI

    Directory of Open Access Journals (Sweden)

    María Portillo Montiel

    2015-04-01

    Full Text Available Esta investigación propone un método para la geolocalización de dispositivos móviles a partir de señales WiFi predeterminadas, prescindiendo del uso del GPS para evitar potenciales problemas de seguridad y malware. El método propuesto, se basa en la técnica conocida como Punto de Triangulación Aproximado (APIT y parte de una discretización del espacio de acción a partir de un conjunto base de emisores de señal WiFi de coordenadas y radios de acción máximos conocidos, para luego construir una rejilla que incluye las zonas de acción conjunta de todos los emisores al momento de activar la aplicación, es posible estimar con gran precisión la ubicación del dispositivo móvil determinando el área de intersección de las señales visibles en el momento. La implementación del algoritmo propuesto exhibe una complejidad temporal cuadrática respecto al tamaño de la rejilla y lineal sobre la cantidad de emisores iniciales.

  14. ¿Hay un hipertexto en esta clase? Dispositivos pedagógicos, tecnología y subjetividad

    Directory of Open Access Journals (Sweden)

    Julieta Armella

    2012-01-01

    Full Text Available En este artículo se presentan resultados de una investigación en torno a los procesos de transformación de los dispositivos pedagógicos, atendiendo a la introducción de las tecnologías de la información y la comunicación (TIC en nuestras sociedades. El trabajo de campo fue realizado en escuelas secundarias públicas de la Región Metropolitana de Buenos Aires. Entendemos que las TIC tienen efectos en nuestras formas de pensar y actuar en el mundo, en los procesos de producción de subjetividad, en cuanto forman parte de la transformación material y simbólica de nuestra vida cotidiana y de las instituciones. Las escuelas no han quedado exentas de ello: hoy se encuentran interpeladas por los modos en que se adquieren los procesos de producción, distribución y acceso a la cultura. Por medio del análisis de episodios nos proponemos describir las modalidades en que los procesos de informatización de la vida social se expresan en el espacio escolar. Ante la pregunta ¿hay un hipertexto en esta clase? procuramos describir algunas de las dinámicas que caracterizan los dispositivos pedagógicos en tiempos digitales y/o postalfabéticos.

  15. Dispositivos móviles y servicios web. Características sociales y comunicativas de su convergencia

    Directory of Open Access Journals (Sweden)

    Francisco Javier Ruíz del Olmo

    2012-04-01

    Full Text Available La convergencia entre los dispositivos móviles y los servicios de la red Internet, aunque prevista, teorizada y resuelta técnicamente desde finales del siglo pasado, se ha venido retrasando por diversas causas hasta, bruscamente, acelerarse y consolidarse irremediablemente a partir de finales del año 2007. Aspectos comerciales, con la entrada de nuevos actores y estrategias al mundo de la comunicación telefónica; de uso y necesidad social, como la comunicación audiovisual personalizada; o de la utilización popular de nuevas aplicaciones red, como la localización geográfica, por ejemplo, coadyuvan a ello. Sin embargo, aún compartiendo muchos aspectos comunicativos y técnicos con la denominada web 2.0, los dispositivos móviles y su uso personalizado, contextual y ubicuo poseen especificidades comunicativas que apenas se empiezan a apuntar en estos nuevos usos cotidianos.

  16. CARACTERIZAÇÃO DE NANOTUBOS DE CARBONO DE PAREDES MÚLTIPLAS AUTOSSUSTENTÁVEIS COMO DISPOSITIVOS SUPERCAPACITORES

    Directory of Open Access Journals (Sweden)

    Joao Vitor da Silva Moreira

    2017-05-01

    Full Text Available Este artigo traz uma análise nas propriedades eletroquímicas dos Nanotubos de Carbono de Paredes Múltiplas (MWCNT’s autossustentáveis, visando sua aplicação na confecção de dispositivos Supercapacitores. Os grupos foram produzidos em um único processo, via deposição química fase-vapor (CVD, e caracterizados através de análise eletroquímica via potenciostato em uma célula de testes especial desenvolvida pelo grupo. Os dados aqui apresentados são um complemento ao trabalho já publicado no Journal of Electronic Materials, e trazem a análise de desempenho do material sob diferentes condições de trabalho. Com isso, este trabalho contribui dando um passo a mais na obtenção de dispositivos Supercapacitores de alta potência, oferecendo uma alternativa com tempo de recarga muito inferior às baterias convencionais.

  17. Intravascular Ultrasound

    Science.gov (United States)

    ... Rounds Seminar Series & Daily Conferences Fellowships and Residencies School of Perfusion Technology Education Resources Library & Learning Resource Center CME Resources THI Journal THI Cardiac Society Register for the Cardiac Society ...

  18. Calculation of sensitivities in electrical systems with SIFLETCA devices; Calculo de sensibilidades en sistemas electricos con dispositivos SIFLETCA

    Energy Technology Data Exchange (ETDEWEB)

    Rubio Marroquin, Gabriel Omar

    2004-03-15

    With the purpose of avoiding the installation of new transmission lines, some researches have proposed the installation of SIFLETCA devices. Therefore in this thesis, different models in steady state of diverse SIFLETCA devices are described, such as: compensator variable series (VSC), static compensator of VArs (SCV), transformer phase shifter (TPS), transformer with changer under load (TWCL) and the universal controller of power flows (UCPF). In addition, it is developed in this thesis the equations used in the Jacobean of the method Newton-Raphson, to solve power flows including SIFLETCA devices. The different applications that are obtained when installing a device, such as prevention of flows in ring, electronic barrier, increment in the transmission capacity and specification of the power flow in transmission lines. On the other hand in the thesis, an analysis of sensitivities of a power system in steady state is developed. Also the control parameters are proposed in the thesis for which the sensitivities are calculated. Also, a performance index is used to measure the degree of congestion of an electrical system. In calculating the sensitivities the obtained results of the power flows are utilized. Four electrical networks are used to find where each SIFLETCA device must be located to reduce the congestion in the system. Also, the method developed in the thesis is compared with a method of sensitivities that uses DC flows, for validation and to show the advantages of using the Newton method in power flows. [Spanish] Con el fin de evitar instalar nuevas lineas de transmision, algunos investigadores han propuesto la instalacion de los dispositivos SIFLETCA. Por lo tanto en esta tesis, se describe diferentes modelos en estado estacionario de diversos dispositivos SIFLETCA, siendo: compensador serie variable (CSV), compensador estatico de VArs (CEV), transformador desfasador (TD), transformador con cambiador bajo carga (TTC) y el controlador universal de flujos

  19. Multicenter assessment of the reproducibility of volumetric radiofrequency-based intravascular ultrasound measurements in coronary lesions that were consecutively stented

    NARCIS (Netherlands)

    Huisman, Jeroen; Egede, R.; Rdzanek, A.; Böse, D.; Erbel, R.; van der Palen, Jacobus Adrianus Maria; von Birgelen, Clemens

    2012-01-01

    To assess in a multicenter design the between-center reproducibility of volumetric virtual histology intravascular ultrasound (VH-IVUS) measurements with a semi-automated, computer-assisted contour detection system in coronary lesions that were consecutively stented. To evaluate the reproducibility

  20. Direct sGC activation bypasses no scavenging reactions of intravascular free oxy-hemoglobin and limits vasoconstriction

    NARCIS (Netherlands)

    N.J.H. Raat (Nicolaas); D.M. Tabima (D. Marcela); P. Specht (Patricia); J. Tejero (Jesús); M.P. Champion (Michael); D.B. Kim-Shapiro (Daniel); J.G. Baust (John ); E.G. Mik (Egbert); M. Hildesheim (Mariana); J.-P. Stasch (Johannes-Peter); E.-M. Becker (Eva-Maria); H. Truebel (Hubert); M.T. Gladwin (Mark)

    2013-01-01

    textabstractAims: Hemoglobin-based oxygen carriers (HBOC) provide a potential alternative to red blood cell (RBC) transfusion. Their clinical application has been limited by adverse effects, in large part thought to be mediated by the intravascular scavenging of the vasodilator nitric oxide (NO) by

  1. Subjetividad y trabajo: el management como dispositivo de gobierno Subjectivity and labour: managemen as government device

    Directory of Open Access Journals (Sweden)

    Marcela Zangaro

    2011-06-01

    Full Text Available Desde hace ya tiempo, en la producción académica enmarcada en la sociología del trabajo y en las teorías de las organizaciones se registra un claro interés respecto de los aportes que los análisis de Michel Foucault permiten realizar a las explicaciones de la relación subjetividad-trabajo. En este artículo se recuperan los últimos aportes foucaultianos vinculados con los conceptos de práctica, tecnología del yo y gobierno. Esta recuperación apunta a sostener que el management o las formas de gestión del trabajo pueden comprenderse como un dispositivo articulador de prácticas de subjetivación que propone a los individuos modos de acción sobre sí mismos. Considerar el management desde esta perspectiva permite ampliar la visión tradicional que de él tienen la psicología y la sociología del trabajo. Dichas perspectivas lo enfocan desde el ángulo definido por un saber-poder que establece principios que definen y controlan un saber-hacer. Estos principios operan como conjunto de obligaciones heteroimpuestas sobre los trabajadores. Considerar al management como una tecnología del yo permite ampliar este enfoque dado que contempla, además de las obligaciones que el management impone al individuo en tanto tecnología de producción-comunicación-poder, obligaciones heteroimpuestas, las obligaciones que los individuos se imponen a sí mismos, obligaciones autimpuestas. Este análisis está basado en la indagación de los significados ideacionales propuestos en textos de gestión.For already time, the academic production placed in the sociology of the work and in the organizations theories registers clear interest respect of the contributions that Michel Foucault's analyses allow to realize to the explanations of the relation subjectivity - labour. This paper recovers the last Foucault´s contributions linked with the concepts of practice, technology of the self and government. This recovery points to hold that management can be

  2. Implantable Medical Devices

    Science.gov (United States)

    ... Artery Disease Venous Thromboembolism Aortic Aneurysm More Implantable Medical Devices Updated:Sep 16,2016 For Rhythm Control ... a Heart Attack Introduction Medications Surgical Procedures Implantable Medical Devices • Life After a Heart Attack • Heart Attack ...

  3. Intercavitary implants dosage calculation

    International Nuclear Information System (INIS)

    Rehder, B.P.

    The use of spacial geometry peculiar to each treatment for the attainment of intercavitary and intersticial implants dosage calculation is presented. The study is made in patients with intercavitary implants by applying a modified Manchester technique [pt

  4. Intravascular Large B-Cell Lymphoma Presenting as Interstitial Lung Disease

    Directory of Open Access Journals (Sweden)

    Elham Vali Khojeini

    2014-01-01

    Full Text Available Intravascular large B-cell lymphoma (IVLBL is a rare subtype of diffuse large B-cell lymphoma that resides in the lumen of blood vessels. Patients typically present with nonspecific findings, particularly bizarre neurologic symptoms, fever, and skin lesions. A woman presented with shortness of breath and a chest CT scan showed diffuse interstitial thickening and ground glass opacities suggestive of an interstitial lung disease. On physical exam she was noted to have splenomegaly. The patient died and at autopsy was found to have an IVLBL in her lungs as well as nearly all her organs that were sampled. Although rare, IVLBL should be included in the differential diagnosis of interstitial lung disease and this case underscores the importance of the continuation of autopsies.

  5. Application of Gafchromic registered film in the dosimetry of an intravascular brachytherapy source

    International Nuclear Information System (INIS)

    Song Haijun; Roa, D. Eduardo; Yue Ning; D'Errico, Francesco; Chen Zhe; Nath, Ravinder

    2006-01-01

    The methodology of brachytherapy source dosimetry with Gafchromic registered MD 55-2 film (ISP Technologies, Inc.) is examined with an emphasis on the nonlinearity of the optical density-dose relation within the dynamic dose range, the radial distance-dependent measurement uncertainty, and the format of data presentation. The specific source chosen for this study was a Checkmate trade mark sign (Cordis Corporation) intravascular brachytherapy system. The two-dimensional dose distribution around the source was characterized by a comprehensive analysis of measurement uncertainties. A comparative analysis of the dosimetric data from the vendor and from the scientific literature showed a substantial consistency of the information available for the Checkmate trade mark sign source. Our two-dimensional dosimetric data for the Checkmate trade mark sign source trains is presented in the form of measured along and away dose tables

  6. Intravascular Papillary Endothelial Hyperplasia (Masson’s Tumor) of the Radial Artery: A Case Report

    International Nuclear Information System (INIS)

    Stark, Christopher; Olsen, Daniel; Morris, Christopher; Bertges, Daniel; Najarian, Kenneth

    2016-01-01

    Intravascular papillary endothelial hyperplasia (IPEH), often referred to as Masson’s tumor, is a benign non-neoplastic vascular lesion of the skin and subcutaneous tissues. Although it is rare, knowledge of the existence of IPEH is important as it can mimic other benign and malignant tumors, most notably angiosarcoma. IPEH remains an incompletely understood entity; however, most consider it to be the result of reactive endothelial proliferation following thrombus formation within a vessel, vascular malformation, or adjacent to a vessel. In this article, we report a case of IPEH arising within an arteriovenous malformation of the radial artery and present accompanying multimodality imaging and pathology figures. We will also describe the clinical presentation, pathophysiology, histology, imaging features, and management of IPEH.

  7. Intravascular large B-cell lymphoma presenting with anasarca-type edema and acute renal failure.

    Science.gov (United States)

    Bilgili, Serap Gunes; Yılmaz, Deniz; Soyoral, Yasemin Usul; Karadag, Ayse Serap; Bayram, Irfan

    2013-09-01

    Intravascular lymphoma (IVL) is a rare extra nodal subtype (usually of B-cell origin) presenting with infiltration of large neoplastic lymphocytes into lumina of blood vessels, leading to vascular occlusion. The early diagnosis is very crucial, however it is usually diagnosed postmortem investigation in most of the cases. A 56-year-old female presented with elevated creatinine level, and anasarca-type edema that superimposed with hard, indurated, erythematous plaques extending to inguinal region, abdomen, anterior aspect of chest, and face. B-cell IVL was confirmed with skin biopsy. The patient had some degree of clinical improvement following chemotherapy. B-cell IVL presenting with anasarca edema was not previously reported in the literature. Even if its rarity, IVL should be considered in the differential diagnosis of renal failure with anasarca edema.

  8. A state-of-the-art review on segmentation algorithms in intravascular ultrasound (IVUS) images.

    Science.gov (United States)

    Katouzian, Amin; Angelini, Elsa D; Carlier, Stéphane G; Suri, Jasjit S; Navab, Nassir; Laine, Andrew F

    2012-09-01

    Over the past two decades, intravascular ultrasound (IVUS) image segmentation has remained a challenge for researchers while the use of this imaging modality is rapidly growing in catheterization procedures and in research studies. IVUS provides cross-sectional grayscale images of the arterial wall and the extent of atherosclerotic plaques with high spatial resolution in real time. In this paper, we review recently developed image processing methods for the detection of media-adventitia and luminal borders in IVUS images acquired with different transducers operating at frequencies ranging from 20 to 45 MHz. We discuss methodological challenges, lack of diversity in reported datasets, and weaknesses of quantification metrics that make IVUS segmentation still an open problem despite all efforts. In conclusion, we call for a common reference database, validation metrics, and ground-truth definition with which new and existing algorithms could be benchmarked.

  9. Intravascular Papillary Endothelial Hyperplasia (Masson’s Tumor) of the Radial Artery: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Stark, Christopher, E-mail: Christopher.stark@uvmhealth.org [University of Vermont Medical Center, Department of Radiology (United States); Olsen, Daniel [Mayo Clinic, Department of Pathology (United States); Morris, Christopher [University of Vermont Medical Center, Department of Radiology (United States); Bertges, Daniel [University of Vermont Medical Center, Department of Surgery (United States); Najarian, Kenneth [University of Vermont Medical Center, Department of Radiology (United States)

    2016-11-15

    Intravascular papillary endothelial hyperplasia (IPEH), often referred to as Masson’s tumor, is a benign non-neoplastic vascular lesion of the skin and subcutaneous tissues. Although it is rare, knowledge of the existence of IPEH is important as it can mimic other benign and malignant tumors, most notably angiosarcoma. IPEH remains an incompletely understood entity; however, most consider it to be the result of reactive endothelial proliferation following thrombus formation within a vessel, vascular malformation, or adjacent to a vessel. In this article, we report a case of IPEH arising within an arteriovenous malformation of the radial artery and present accompanying multimodality imaging and pathology figures. We will also describe the clinical presentation, pathophysiology, histology, imaging features, and management of IPEH.

  10. The role of the adventitia in the arterial response to angioplasty: the effect of intravascular radiation

    International Nuclear Information System (INIS)

    Wilcox, Josiah N.; Waksman, Ron; King, Spencer B.; Scott, Neal A.

    1996-01-01

    Purpose: In the current series of experiments we have characterized cell proliferation leading to vascular lesion formation in a porcine model for post-angioplasty restenosis and examined the mechanism of action of intravascular beta irradiation in the prevention of lesion formation in this model. Methods and Materials: Juvenile male pigs were subjected to balloon overstretch injury of the left anterior descending and circumflex coronary arteries using clinical angioplasty catheters. Proliferating cells were labelled by injections of 50 mg/kg of bromo-deoxyuridine (BrDU) 24, 16 and 8 hrs prior to sacrifice and were detected by immunohistochemistry using a specific antibody to BrDU. In some cases, BrDU was given as a pulse 3 days after angioplasty and the animals sacrificed on day 14 to follow the migration of the cells which had proliferated earlier. Characterization of the proliferating cells was performed by immunohistochemistry using antibodies to specific cytoskeletal proteins specific for smooth muscle cells and myofibroblasts. Some vessels were treated at the time of angioplasty with 14 or 28 Gy (to a depth of 2 mm) intravascular irradiation using a flexible catheter with a pure beta emitter 90 SR/Y and the effect on cell proliferation and terminal transferase-mediated UTP nick-end labelling (TUNEL) examined 3 or 7 days later. Results: The first major site of cell proliferation between 2-3 days after angioplasty is the adventitia and not the medial wall. Seven days after angioplasty cell proliferation is predominant in the neointima and is reduced in the media and adventitia. Differential staining with antibodies directed against smooth muscle alpha actin and other cytoskeletal proteins indicates that the proliferating adventitial cells are myofibroblasts. Pulse label studies with BrDU indicates that the proliferating adventitial myofibroblasts migrate into the neointima and contribute to the mass of the restenosis lesion. Fourteen days after angioplasty the

  11. Specific features of red blood cell morphology in hemolytic disease neonates undergoing intrauterine intravascular blood transfusion

    Directory of Open Access Journals (Sweden)

    A. V. Ivanova

    2016-01-01

    Full Text Available The paper presents data on the characteristics of red blood cell morphology in infants who have undergone intrauterine intravascular blood transfusion for hemolytic disease of the fetus. The infants are shown to have a reduction in the mean volume of red blood cells and in their mean level of hemoglobin, a decrease in the fraction of fetal hemoglobin and an increase in oxygen tension at half saturation. The above morphological characteristics of red blood cells remain decreased during the neonatal period after exchange transfusion or others, as clinically indicated, which seems to suggest that the compensatory-adaptive mechanisms to regulate hematopoiesis are exhausted and a donor’s red blood cells continue to be predominant.

  12. Histopathological approach for diagnosis of intravascular leiomyosarcoma of the femoral vein

    Directory of Open Access Journals (Sweden)

    Gaurav Singal

    2016-04-01

    Full Text Available Malignant tumors arising from venous walls in the lower extremities are uncommon and intravascular leiomyosarcoma represents only a small proportion and rare of soft tissue leiomyosarcoma. All publications in the literature are of small clinical series or case reports. We present a case of primary leiomyosarcoma of the femoral vein in a 40 year old man; which is a rare lesion with less than 40 cases reported. The patient presented with swelling and localized leg pain. The diagnosis was made histopathologically, the tumor was resected, vascular reconstruction was performed, and for postoperative radiation therapy and chemotherapy patient was referred to the oncologist. Primary leiomyosarcoma of a major peripheral artery is extremely rare, and this report share the clinical presentation, histopathological findings, treatment, and prognosis in these patients

  13. Splenic angiomyxoma with intravascular tumor embolus in a dog: a case report.

    Science.gov (United States)

    Lee, Eun-Mi; Kim, Ah-Young; Lee, Eun-Joo; Park, Jin-Kyu; Kim, Tae-Hwan; Park, Se-Il; Jeong, Kyu-Shik

    2016-07-01

    A 13-year-old castrated male Yorkshire terrier dog had a soft splenic mass, which measured 11 cm in the greatest diameter. Microscopically, the parenchyma of the spleen was completely replaced by myxoid substances. Numerous spindle and stellate cells were loosely arranged in the myxoid stroma, and variable vessels of variable sizes were observed in a loose matrix with poorly defined margins. Immunohistochemical analysis showed that tumor cells were positive for desmin and alpha-SMA, but negative for S-100. Interestingly, intravascular tumor embolus with positive α-SMA expression was observed. This case is meaningful, because angiomyxoma, a rare tumor of dogs, occurs in the spleen. Even in human cases, splenic angiomyxoma was not reported.

  14. Intravascular ultrasound assessment of remodelling and reference segment plaque burden in type-2 diabetic patients

    DEFF Research Database (Denmark)

    Jensen, Lisette Okkels; Thayssen, Per; Mintz, Gary S

    2007-01-01

    AIMS: Intravascular ultrasound (IVUS) assesses arterial remodelling by comparing the lesion external elastic membrane (EEM) with the reference segments; however, reference segments are rarely disease-free. The aim was to assess lesion and reference segment remodelling and plaque burden in patients...... with type-2 diabetes mellitus. METHODS AND RESULTS: We used pre-intervention IVUS to study 62 de novo lesions in 43 patients with type-2 diabetes mellitus. The lesion site was the image slice with the smallest lumen cross-sectional area (CSA). The proximal and distal reference segments were the most normal...... size [slope = -0.12 (95% CI -0.17 to -0.07); P type-2 diabetes mellitus. CONCLUSION: Lesions in type-2 diabetic patients are different from previous reports in non-diabetics. Lesions in type-2 diabetics are characterized by a large reference segment plaque burden...

  15. Early Blood Transfusion and Resolution of Disseminated Intravascular Coagulation Associated with Massive Subgaleal Hemorrhage.

    Science.gov (United States)

    Modanlou, Houchang; Hutson, Shandee; Merritt, Allan Thurman

    2016-01-01

    A male infant delivered to a primipara woman following vacuum applications. He was vigorous at birth, with small caput and scalp bruising. His head was enlarging; he became pale with respiratory distress. Subgaleal hemorrhage (SGH) was suspected. His hematocrit was noted to be 26.2 percent prior to transfusion of O, Rh-negative blood (40 mL/kg). Moderate disseminated intravascular coagulation (DIC) was noted at 12 hours of age. Posttransfusion of fresh frozen plasma (FFP), his condition became stable, and DIC gradually resolved. Head magnetic resonance imaging did not show intracranial hemorrhage. Although one episode of seizures was noted, electroencephalogram was normal. With the application of obstetric vacuum, we recommend that the neonatal health care professionals frequently evaluate the infant's condition. In light of developing fluctuant subgaleal fluid associated with pallor, anemia, metabolic acidosis, and respiratory distress, immediate blood transfusion is warranted. In the presence of DIC, transfusion of FFP is beneficial.

  16. Catheter design optimization for practical intravascular photoacoustic imaging (IVPA) of vulnerable plaques

    Science.gov (United States)

    Iskander-Rizk, Sophinese; Wu, Min; Springeling, Geert; Mastik, Frits; Beurskens, Robert H. S. H.; van der Steen, Antonius F. W.; van Soest, Gijs

    2018-02-01

    Intravascular photoacoustic/ultrasound imaging (IVPA/US) can image the structure and composition of atherosclerotic lesions identifying lipid-rich plaques ex vivo and in vivo. In the literature, multiple IVPA/US catheter designs were presented and validated both in ex-vivo models and preclinical in-vivo situations. Since the catheter is a critical component of the imaging system, we discuss here a catheter design oriented to imaging plaque in a realistic and translatable setting. We present a catheter optimized for light delivery, manageable flush parameters and robustness with reduced mechanical damage risks at the laser/catheter joint interface. We also show capability of imaging within sheath and in water medium.

  17. An automated approach for segmentation of intravascular ultrasound images based on parametric active contour models

    International Nuclear Information System (INIS)

    Vard, Alireza; Jamshidi, Kamal; Movahhedinia, Naser

    2012-01-01

    This paper presents a fully automated approach to detect the intima and media-adventitia borders in intravascular ultrasound images based on parametric active contour models. To detect the intima border, we compute a new image feature applying a combination of short-term autocorrelations calculated for the contour pixels. These feature values are employed to define an energy function of the active contour called normalized cumulative short-term autocorrelation. Exploiting this energy function, the intima border is separated accurately from the blood region contaminated by high speckle noise. To extract media-adventitia boundary, we define a new form of energy function based on edge, texture and spring forces for the active contour. Utilizing this active contour, the media-adventitia border is identified correctly even in presence of branch openings and calcifications. Experimental results indicate accuracy of the proposed methods. In addition, statistical analysis demonstrates high conformity between manual tracing and the results obtained by the proposed approaches.

  18. Comparison of angiography and intravascular ultrasound before and after balloon angioplasty of the femoropopliteal artery

    International Nuclear Information System (INIS)

    Lankeren, Winnifred van; Gussenhoven, Elma J.; Pieterman, Herman; Sambeek, Marc R. H. M. van; Lugt, Aad van der

    1998-01-01

    Purpose: To compare angiographic and intravascular ultrasound (IVUS) data before and after balloon angioplasty (PTA) of the femoropopliteal artery.Methods: Qualitative and quantitative analyses were performed on corresponding angiographic and IVUS levels obtained from 135 patients.Results: IVUS detected more lesions, calcified lesions, and vascular damage than angiography. Sensitivity of angiography was good for the presence of a lesion (84%), moderate for eccentric lesions (53%) and for vascular damage (52%), and poor for calcified lesions (30%). The increase in angiographic diameter stenosis was associated with a decrease in lumen area and increase in percentage area stenosis on IVUS.Conclusions: Angiography is less sensitive than IVUS for detecting lesion eccentricity, calcified lesions, and vascular damage. Presence of a lesion and amount of plaque were underestimated angiographically. Only before PTA was good agreement found between angiographic diameter stenosis and lumen size on IVUS.

  19. Perspectives on Imaging the Left Main Coronary Artery Using Intravascular Ultrasound and Optical Coherence Tomography

    Directory of Open Access Journals (Sweden)

    Harry C Lowe

    2015-01-01

    Full Text Available Percutaneous Coronary Intervention (PCI for significant left main coronary artery (LMCA stenosis is increasingly being viewed as a viable alternative to Coronary Artery Bypass Grafting (CABG (1. This is leading to an expectation of increasing numbers of such procedures, with a consequent focus on both the ability to image both lesion severity, and assess more accurately the results of PCI. While there have been advances in physiologic assessment of left main severity using fractional flow reserve (FFR, imaging of the LMCA using Intravascular Ultrasound (IVUS and more recently Optical Coherence Tomography (OCT has the specific advantage of being able to provide detailed anatomical information both pre and post PCI, such that it is timely to review briefly the current status of these two imaging technologies in the context of LMCA intervention.

  20. Intravascular forward-looking ultrasound transducers for microbubble-mediated sonothrombolysis.

    Science.gov (United States)

    Kim, Jinwook; Lindsey, Brooks D; Chang, Wei-Yi; Dai, Xuming; Stavas, Joseph M; Dayton, Paul A; Jiang, Xiaoning

    2017-06-14

    Effective removal or dissolution of large blood clots remains a challenge in clinical treatment of acute thrombo-occlusive diseases. Here we report the development of an intravascular microbubble-mediated sonothrombolysis device for improving thrombolytic rate and thus minimizing the required dose of thrombolytic drugs. We hypothesize that a sub-megahertz, forward-looking ultrasound transducer with an integrated microbubble injection tube is more advantageous for efficient thrombolysis by enhancing cavitation-induced microstreaming than the conventional high-frequency, side-looking, catheter-mounted transducers. We developed custom miniaturized transducers and demonstrated that these transducers are able to generate sufficient pressure to induce cavitation of lipid-shelled microbubble contrast agents. Our technology demonstrates a thrombolysis rate of 0.7 ± 0.15 percent mass loss/min in vitro without any use of thrombolytic drugs.

  1. Neuroendocrine and renal effects of intravascular volume expansion in compensated heart failure

    DEFF Research Database (Denmark)

    Gabrielsen, A; Bie, P; Holstein-Rathlou, N H

    2001-01-01

    To examine if the neuroendocrine link between volume sensing and renal function is preserved in compensated chronic heart failure [HF, ejection fraction 0.29 +/- 0.03 (mean +/- SE)] we tested the hypothesis that intravascular and central blood volume expansion by 3 h of water immersion (WI) elicits...... sustained angiotensin-converting enzyme inhibitor therapy, n = 9) absolute and fractional sodium excretion increased (P Renal free water clearance increased during WI in control subjects but not in HF......, albeit plasma vasopressin concentrations were similar in the two groups. In conclusion, the neuroendocrine link between volume sensing and renal sodium excretion is preserved in compensated HF. The natriuresis of WI is, however, modulated by the prevailing ANG II and Aldo concentrations. In contrast...

  2. The cerebral intravascular enhancement sign is not specific: a contrast-enhanced MRI study

    Energy Technology Data Exchange (ETDEWEB)

    Bakshi, R.; Kinkel, W.R.; Bates, V.E.; Mechtler, L.L.; Kinkel, P.R. [Lucy Dent Imaging Center, University at Buffalo, NY (United States)

    1999-02-01

    The intravascular enhancement (IVE) sign, also known as the ``arterial enhancement sign``, is an abnormal finding in the brain on contrast-enhanced MRI studies. IVE has been described in arterial cerebrovascular disorders, most commonly in acute or subacute arterial ischemic infarcts. However, the specificity of this sign has not been established. We describe four patients with disorders other than arterial strokes in whom gadolinium-enhanced high-field (1.5 T) MRI suggested IVE. The conditions were herpes simplex viral encephalitis, idiopathic cerebellitis, pneumococcal meningitis, and superior sagittal sinus thrombosis with venous infarction. IVE in these cases may be due to multiple factors, including arterial, venous, perivascular, and leptomeningeal or sulcal contrast medium accumulation. Our observations suggest that arterial ischemia, previously described as the cardinal cause of IVE, probably does not explain all instances, and urge caution in interpreting this sign as a specific MRI manifestation of acute arterial infarction or ischemia. (orig.) With 4 figs., 1 tab., 44 refs.

  3. Intravascular papillary endothelial hyperplasia of the extremities: MR imaging findings with pathologic correlation

    International Nuclear Information System (INIS)

    Lee, Sang Hoon; Suh, Jin-Suck; Lim, Byung Il; Yang, Woo Ick; Shin, Kyoo-Ho

    2004-01-01

    We report the MRI findings of three cases of intravascular papillary endothelial hyperplasia (IPEH) of the extremities with correlation of the pathologic findings. The IPEH is a non-neoplastic reactive lesion within the vessels and is commonly associated with thrombi. Signal intensity of the IPEH is complex due to the thrombi and the PEH itself. The thrombi are characterized by a slightly hyperintense signal on T1- and T2-weighted images compared with that of muscle when it comes at the medium stage of hemorrhage. Papillary endothelial hyperplastic tissue appears either as iso- or hyperintense to the muscle on T2- and T1-weighted images and shows variable enhancement on Gd-DTPA-enhanced images. (orig.)

  4. Educar y Castigar. Dispositivos de control social en la estrategia de formación del ciudadano en Cartagena (Colombia: 1880-1900.

    Directory of Open Access Journals (Sweden)

    William Malkún Castillejo

    2015-01-01

    Full Text Available En este artículo se analiza como la elite cartagenera en pleno periodo de la Regeneración construyó una serie de dispositivos de control social que buscaban contrarrestar los altos índices de criminalidad y trasgresión social y a la vez impulsar la construcción del nuevo ciudadano cartagenero. Todo este proyecto estaba soportado en dos dispositivos preventivos y punitivos de intervención social. Un dispositivo policivo y un dispositivo educativo. El objetivo era el impulso de los valores urbanos modernos entre la población cartagenera e igualmente la construcción simbólica del nuevo ciudadano cartagenero, virtuoso, trabajador, educado, católico y respetuoso de la autoridad y del ordenamiento jurídico. Simultáneamente se implementó entre los cartageneros la destrucción simbólica del anti-ciudadano y sus valores negativos: la vagancia, el juego, la mala educación, la trasgresión y su tendencia al delito.

  5. Comparativa de la reparación valvular mitral y el dispositivo MitraClip® en el tratamiento de la insuficiencia mitral severa

    Directory of Open Access Journals (Sweden)

    Isabel Pernía-Oreña

    2017-03-01

    Conclusiones: El dispositivo MitraClip®, en este grupo de bajo riesgo, mostró peores resultados con mayor mortalidad, reingresos, descompensaciones y alta tasa de insuficiencia mitral residual. Podría ser una alternativa en casos desestimados de cirugía.

  6. El trabajo que no se ve. Dispositivos de inserción sociolaboral para mujeres inmigrantes en Barcelona.

    Directory of Open Access Journals (Sweden)

    Laura Cristina Yufra

    2016-01-01

    Full Text Available El presente trabajo pretende prestar atención a los modos en los que lassociedades de instalación de inmigrantes se dirigen hacia aquellos que son consideradoscomo “otros”; en este caso, las mujeres inmigrantes. Concretamente,nuestra atención se centra en los dispositivos de intervención social que tienenpor finalidad facilitar la inserción sociolaboral de estas mujeres. El trabajo decampo, de carácter exploratorio, ha sido llevado a cabo en dos entidades queposeen dispositivos de inserción sociolaboral para mujeres inmigrantes, ambosubicados en el Barrio del Raval de la ciudad de Barcelona. Las técnicas utilizadashan sido la observación participante y la entrevista. En la descripciónde algunos ejemplos de las dinámicas que se producen en dichos dispositivosidentificamos cómo se les solicita a las mujeres inmigrantes que realicen ajustesy/o modificaciones de sus modos de actuar para así hacer un uso correcto de losdispositivos de inserción y también para favorecer su inserción sociolaboral. Talespedidos son analizados a través de las categorías teóricas de Pierre Bourdieude habitus y violencia o dominación simbólica, revisitadas por algunos de suscríticos. Las mencionadas nociones permiten reflexionar sobre algunas de lasinteracciones que se producen en dichos dispositivos y sobre la complejidad delproceso de incorporación de las mujeres migrantes a la sociedad de instalación.Del trabajo de campo emerge la orientación de las mujeres inmigrantes hacia lostrabajos domésticos y del cuidado, además de cierta desvalorización de la lenguamaterna de las usuarias y de las manifestaciones visibles de su religión. Aunquese advierte que no son las únicas formas posibles de actuación e interacción, se argumenta sobre la importancia de reconocer la existencia de formas jerarquizadasde interacción, con el objetivo de contribuir a una mirada crítica sobre lasdisciplinas involucradas en la intervención social.

  7. Implantable electronic medical devices

    CERN Document Server

    Fitzpatrick, Dennis

    2014-01-01

    Implantable Electronic Medical Devices provides a thorough review of the application of implantable devices, illustrating the techniques currently being used together with overviews of the latest commercially available medical devices. This book provides an overview of the design of medical devices and is a reference on existing medical devices. The book groups devices with similar functionality into distinct chapters, looking at the latest design ideas and techniques in each area, including retinal implants, glucose biosensors, cochlear implants, pacemakers, electrical stimulation t

  8. Establishment of virtual three-dimensional model for intravascular interventional devices and its clinical value

    International Nuclear Information System (INIS)

    Wei Xin; Zhong Liming; Xie Xiaodong; Wang Chaohua; You Jian; Hu Hong; Hu Kongqiong; Zhao Xiaowei

    2012-01-01

    Objective: To explore virtual three-dimensional (3D) model for intravascular interventional devices,the method of preoperative simulation and its value in clinical work. Methods: The virtual models including catheter, guide wire, stent and coil were established by using the 3D moulding software of 3D Studio MAX R3. The interventional preoperative simulation was performed on personal computer including 21 patients of cerebral aneurysm embolization (anterior communicating artery 5, posterior communicating artery 10,middle cerebral artery 3, internal carotid artery 2, and vertebral artery 1), during interventional procedures, the surgeon relied on the simulation results for plastic micro-guide wire, catheter and the release of micro-coils and stents. Results: (1) All the virtual instruments and real instruments had similar shape,the overall tine for constructing virtual model was about 20 hours. The preoperative simulation took 50 to 80 minutes. (2) The simulation result of catheter insertion in the 18 cases had relevant value to guide micro-catheter, molding micro-guide wire tip, and shortened the operating time. For embolization, the simulation results of filling coil and releasing stent were similar to surgical results in 76% of the patients (16/21). (3)For teaching and training, 93% (38/41) of doctors in training believed that preoperative simulation facilitated the understanding of surgery. Conclusions: The method of virtual model of intravascular interventional devices was reliable. The preoperative simulation results could be used to guide practical clinical operation with relatively high degree of similarity, and could play a role in promoting researches on interventional virtual operations. (authors)

  9. Intravascular large B-cell lymphoma of the kidney: A case report

    Directory of Open Access Journals (Sweden)

    Jia Nan

    2011-09-01

    Full Text Available Abstract We report a 41-year-old Chinese woman with intravascular large B-cell lymphoma diagnosed by percutaneous renal biopsy. The patient was admitted to Nanfang Hospital of Southern Medical University, Guangzhou, China with complaints of high spiking fever for a month and bilateral lower limb fatigue with difficulty ambulating for the past 5 months. She had renal dysfunction with a total urinary protein of 5.61 g/dL (56.1 g/L, serum albumin of 2.89 g/dL (28.9 g/L, urea nitrogen of 2.24 mg/dL (1.6 mmol/L, and serum creatinine of 0.54 mg/dL (48 μmol/L. Bone marrow biopsy revealed myeloproliferative disorder without abnormal myeloid or lymphocytic proliferation. Positron Emission Tomography-Computed Tomography (PET-CT showed marked bilateral swelling and enlargement of the renal parenchyma with splenic enlargement and involvement of multiple vertebrae. Percutaneous renal biopsy showed island-like accumulations of medium to large lymphoid cells in many areas of the interstitium, with round vesicular nuclei containing distinct basophilic nucleoli. Immunohistochemical analysis together with other supportive investigation confirmed the diagnosis of intravascular large B-cell lymphoma. Ten days later, she was started on chemotherapy with CHOP (cyclophosphamide, doxorubicin, leurocristime and prednisone for a week. Palliative radiotherapy DT 40Gy/20F with other supportive treatment was provided for metastatic foci in the medullary cavity of the sternum, T1-T7. The patient regained muscle strength in both lower limbs and was able to walk again after three weeks. The patient was discharged after hepatic and renal function and proteinuria values had returned to normal. Follow-up data shows the patient to be alive nine months after discharge.

  10. Prediction of postpercutaneous coronary intervention myocardial infarction: insights from intravascular imaging, coronary flow, and biomarker evaluation.

    Science.gov (United States)

    Hoole, Stephen P; Hernández-Sánchez, Jules; Brown, Adam J; Giblett, Joel P; Bennett, Martin R; West, Nick E J

    2018-05-01

    Percutaneous coronary intervention-induced myocardial infarction (PMI) has prognostic significance. Identifying patients at high risk for PMI is desirable as it may alter strategy and facilitate early preventative therapy. We therefore sought to establish whether preprocedural demographic, interventional (plaque characteristics and coronary microcirculatory function), and inflammatory, endothelial damage, and platelet-derived biomarker data could predict the risk of PMI. We performed target vessel pressure wire to assess fractional flow reserve, index of microcirculatory resistance (IMR) and coronary flow reserve, plaque characterization by virtual histology intravascular ultrasound, and assayed peripheral biomarkers before uncomplicated PCI in 88 patients. We then analyzed post-PCI cardiac troponin level to adjudicate PMI based on the third universal definition of myocardial infarction. Overall incidence of PMI was 27%. Women [10/15 (66%) vs. 14/73 (19%), PPMI. Preprocedural coronary flow reserve was lower in individuals with a subsequent PMI (1.8±1.2 vs. 2.1±1.3. P=0.03), and patients with higher pre-PCI IMR were more likely to sustain PMI [IMR>22: 10/23 (44%) vs. ≤22: 14/65 (22%), P=0.04], although neither was predictive after multivariate analysis. Plaque characterization by virtual histology intravascular ultrasound did not discriminate those at risk of PMI. However, peripheral venous interleukin (IL)-18 and IL-8 levels were independently negatively and positively associated with PMI, respectively. Women and those with low BMI, particularly when associated with high IL-8 and low IL-18 levels, appear to be at increased risk of PMI.

  11. The effects of serial intravascular transfusions in ascitic/hydropic RhD-alloimmunized fetuses.

    Science.gov (United States)

    Craparo, F J; Bonati, F; Gementi, P; Nicolini, U

    2005-02-01

    To evaluate the effects of serial intravascular transfusions on RhD-alloimmunized fetuses with ascites/hydrops at the time of the first transfusion by measuring multiple hematological/biochemical blood variables. Thirty-one singleton pregnancies were referred for management of RhD alloimmunization. Seven fetuses had hydrops on presentation and were transfused immediately. The remainder underwent weekly ultrasound examinations, and fetal blood sampling and transfusion were performed on development of ascites. In the 104 samples collected overall from the 31 fetuses, glucose, uric acid, urea, creatinine, total protein, total and direct bilirubin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltransferase, alkaline phosphatase, lactic dehydrogenase, amylase, pseudocholinesterase (PCHE), creatine kinase, triglycerides and cholesterol were measured and compared with a reference range for non-anemic fetuses. The median gestational age at first transfusion was 26 (range, 18-34) weeks. There were three fetal losses after the first transfusion, two of which were due to procedure-related complications; one further loss occurred. At the first transfusion fetal hematocrit, pO2, total protein, PCHE, creatinine and urea concentrations were significantly decreased compared to reference data, while total and direct bilirubin, AST, ALT, amylase, triglyceride and uric acid concentrations were increased. In all surviving fetuses ascites/hydrops had disappeared by the second transfusion. Fetal pO2, total protein, AST, ALT and PCHE concentrations had normalized by the third transfusion. Correction of fetal anemia did not affect the other variables. RhD-alloimmunized fetuses with ascites/hydrops at the time of the first transfusion had a survival rate of 87%. Alterations of several biochemical fetal blood indices are present at the first sampling/transfusion, but most variables normalize with intravascular transfusions. Copyright 2005 ISUOG.

  12. Evaluation of cerebral intravascular blood flow by time density curve study of intravenous digital subtraction angiography

    Energy Technology Data Exchange (ETDEWEB)

    Imamura, Toru; Kogure, Kyuya (Tohoku Univ., Sendai (Japan). School of Medicine); Sekine, Teiko; Satoh, Kei; Endoh, Minoru; Tsuburaya, Kenji; Hoshi, Akihiko

    1992-01-01

    Time density curve (TDC) can be reconstructed from the data of intravenous digital subtraction angiography (IVDSA). We evaluated peak time (PT) and modal transit time (MOTT) of the TDC as the probable indicator of cerebral intravascular blood flow. Cerebral IVDSA and single photon emission CT (SPECT) were performed on 12 patients with ischemic cerebrovascular disease, which consisted of 3 internal carotid artery (ICA) occlusions, one middle cerebral artery (MCA) occlusion, one anterior cerebral artery (ACA) branch occlusion and 7 lacunar infarctions. We classified former 4 patients as occlusion group and latter 8 as reference group. In 3 patients (2 ICA and one MCA occlusions), SPECT study revealed definite hypoaccumulation in the MCA territory of occlusive side. Two regions of interest (ROI) were placed on the territories of right and left middle cerebral arteries in the frontal view of cerebral IVDSA. Digital data processor fitted {gamma} curve to the TDC of each ROI, and calculated PT and MOTT. The absolute lateralities of PT and MOTT of MCA territory was significantly (p<0.05) larger in occlusion group than reference group. Patients with hypoaccumulation in SPECT had significantly (p<0.02) larger laterality of MOTT than patients with isoaccumulation. One ICA occluded patient without hypoaccumulation in corresponding MCA territory had relatively small laterality of MOTT similar to the patients of ACA branch occlusion and lacunar infarction. These results suggest that PT and MOTT are possible to detect the laterality of the intravascular blood flow in MCA territories caused by major artery occlusion. Cerebral TDC study of IVDSA may be useful in some clinical therapeutic situations such as hemodilution or intra-arterial thrombolysis, and worth further clinical evaluation. (author).

  13. Nitric Oxide Release for Improving Performance of Implantable Chemical Sensors - A Review.

    Science.gov (United States)

    Cha, Kyoung Ha; Wang, Xuewei; Meyerhoff, Mark E

    2017-12-01

    Over the last three decades, there has been extensive interest in developing in vivo chemical sensors that can provide real-time measurements of blood gases (oxygen, carbon dioxide, and pH), glucose/lactate, and potentially other critical care analytes in the blood of hospitalized patients. However, clot formation with intravascular sensors and foreign body response toward sensors implanted subcutaneously can cause inaccurate analytical results. Further, the risk of bacterial infection from any sensor implanted in the human body is another major concern. To solve these issues, the release of an endogenous gas molecule, nitric oxide (NO), from the surface of such sensors has been investigated owing to NO's ability to inhibit platelet activation/adhesion, foreign body response and bacterial growth. This paper summarizes the importance of NO's therapeutic potential for this application and reviews the publications to date that report on the analytical performance of NO release sensors in laboratory testing and/or during in vivo testing.

  14. Dispositivo securitario en un espacio barrial. La práctica policial de los controles de identidad

    Directory of Open Access Journals (Sweden)

    García García, Sergio

    2012-06-01

    Full Text Available This article discusses the management of the security apparatus and its differential application to population taking as a paradigmatic case the identity controls conducted by the police in the public spaces. The security apparatus, understood as a set of imaginaries, architectures, discourses and practices which emphasize “citizen safety” as a key point, is marked by two logics: the logic of neo-liberal management and the professional culture of security agents. Although these two logics arise from very different civilizational projects, they come together in a space like Carabanchel –along with other forms of ‘expertise’– to delineate the figure of the citizen and of the “non-citizen” based on the differential relation established between neighbors through a process of class-differentiation and racialization. Thus the migratory process, problematized by the media and by institutions, has become a special object of control and surveillance shaping the differences upon the basis of which ‘legitimate’ identities are reconstructed in the neighborhood (“good citizens”. This proposal will describe how both of these logics of ‘security’ work, building a guilty subject of the victim neighbourhood –the “foreigner”– through selective police identity checks in public spaces.

    El presente artículo aborda el funcionamiento del dispositivo securitario y su aplicación diferencial sobre la población tomando como caso paradigmático los controles de identidad que efectúa la policía en los espacios comunes de un barrio de Madrid. El dispositivo securitario, entendido como el conjunto de imaginarios, arquitecturas, discursos y prácticas que sitúan en un lugar protagónico la llamada “seguridad ciudadana”, está atravesado por dos lógicas: la de la gestión neoliberal y la de la cultura profesional de los agentes de seguridad. Aunque sendas lógicas partan de proyectos civilizatorios muy distintos entre

  15. A “Guerra da Lagosta” , o “Dispositivo Pós-Colonial” e o Golpe de 1964.

    Directory of Open Access Journals (Sweden)

    tulio souza muniz

    2013-11-01

    Full Text Available Este artigo aborda conflitos económicos e diplomáticos internacionais que, no discurso jornalístico e no imaginário social, são precipitadamente classificados como “guerras”. Parece ter sido o caso do conflito entre Brasil e a França, em 1963, que culminou com o que a imprensa chamou de “a guerra da lagosta”, pretexto para eclosão do que chamarei “Dispositivo Pós-Colonial” (DPC e uma espécie de laboratório para o enfrentamento dos militares brasileiros com o governo João Goulart.

  16. Entornos personalizados de aprendizaje (EPA para dispositivos móviles: situaciones de aprendizaje y evaluación

    Directory of Open Access Journals (Sweden)

    Zulma Cataldi

    2013-01-01

    Full Text Available El Informe Horizon para Iberoamérica prevé que en tres años la tecnología móvil, tendrá un potencial de impacto en la enseñanza, el aprendizaje, la investigación y la expresión creativa en el ámbito educativo global. La evolución actual de los dispositivos móviles da cuenta de las posibilidades muy interesantes disponibles, ya que permiten elaborar ambientes de aprendizaje personalizados para cada necesidad. En esta comunicación se definen y se describen los entornos personalizados de aprendizaje (EPA y se da un ejemplo genérico y otro particular de aplicaciones que se probaron en smartphones y tablets.

  17. Aplicativos para dispositivos móveis: uma potencial ferramenta para médicos e alunos?

    Directory of Open Access Journals (Sweden)

    Isabella Pagetti de Oliveira

    2014-10-01

    Full Text Available Introdução: Ao utilizarem aplicativos em dispositivos móveis, alunos e profissionais da área da saúde podem ter acesso rápido às informações médicas. Questiona-se o quanto tais informações possuem embasamento científico e se tais inovações tecnológicas contribuem, substituem ou prejudicam o exercício da medicina; Objetivo: O objetivo deste trabalho foi avaliar a qualidade dos aplicativos desenvolvidos para a área da saúde; Metodologia: Por meio de um questionário impresso, que aborda questões relacionadas ao uso de smartphones e dos aplicativos da área médica contidos nestes dispositivos, foram entrevistados internos, residentes e docentes da FCMS-PUC-SP, campus Sorocaba. Além disso, os cinco aplicativos mais citados pelos entrevistados foram avaliados qualitativamente por profissionais de diversas áreas médicas e os dados comparados às informações fornecidas pelos seus desenvolvedores; Resultados: Verificou-se que a maioria dos participantes possui um smartphone e utiliza aplicativos da área médica diariamente, principalmente com finalidades diagnósticas e de tratamento. Notou-se uma correlação positiva entre a avaliação dos especialistas e o que é proposto pela empresa que desenvolve os aplicativos; Conclusões: Muitos médicos vêem grande potencial na utilização destas tecnologias na prática médica, que tendem a trazer benefícios aos médicos e, também, aos pacientes.

  18. Los jóvenes como usuarios de aplicaciones de marca en dispositivos móviles

    Directory of Open Access Journals (Sweden)

    Francisco Javier Ruiz del Olmo

    2014-07-01

    Full Text Available El presente trabajo analiza el papel de los jóvenes consumidores en el contexto de los nuevos procesos comunicativos que surgen de tecnologías emergentes: el uso de las aplicaciones de marca en los dispositivos móviles. Éstos incorporan funcionalidades sociales y comunicativas cada vez más complejas y, entre ellas, las aplicaciones para teléfonos inteligentes que vinculan publicidad comercial y pagos forman un campo novedoso pero de interés prioritario para distintos actores comunicativos, como son las marcas comerciales, los servicios bancarios y las propias compañías tecnológicas. En ese contexto la presente investigación describe y codifica cualitativamente cómo los usuarios entienden, perciben y utilizan, como prosumidores, las aplicaciones de marca corporativa y los pagos. Para ello se aplican técnicas de investigación en cuatro grupos focales, de edades comprendidas entre los 18 y 24 años, compuestos por jóvenes universitarios españoles estudiantes en Comunicación, como usuarios que muestran una predisposición y una adopción temprana de estas prácticas. Las respuestas de las reuniones del grupo de discusión permitieron una clasificación de las prácticas comunicativas. En conclusión, se constata una alta predisposición de estos consumidores activos por interactuar con contenidos comerciales, estableciendo redes sociales bajo el amparo de una cultura e imagen de marca, como forma de cohesión grupal. Otros usos se relacionan con el entretenimiento y la información, al tiempo que aún se muestran reticentes al pago de productos o servicios mediante el dispositivo móvil.

  19. [Optimal intravascular brachytherapy: safety and radiation protection, reliability and precision guaranteed by guidelines, recommendations and regulatory requirements].

    Science.gov (United States)

    Quast, Ulrich; Kaulich, Theodor W; Lorenz, Joachim

    2002-02-01

    The success of intravascular brachytherapy relies entirely on the interdisciplinary approach. Interventional cardiologists, radiation oncologists and medical physicists must form a team from day 1. All members of the team need special knowledge and regular training in the field of vascular radiation therapy. Optimization of intravascular brachytherapy requires the use of standardized methods of dose specification, recording and reporting. This also implies using standardized methods of source calibration in terms of absorbed dose to water and having methods for simple internal control of the dosimetric quantities of new or replaced sources. Guidance is offered by international recommendations (AAPM TG 60, DGMP Report 16, NCS and EVA GEC-ESTRO). LEGAL REQUIREMENTS FOR RADIATION PROTECTION--WHAT'S NEW?: In Europe, new legal requirements on radiation protection issues have to be fulfilled. For Germany, the revised "Strahlenschutzverordnung" has been released recently. Nearly all organizational and medical processes are affected. For intravascular brachytherapy, several changes of requirements have to be considered. However, to follow these requirements does not cause serious problems. DGMP REPORT 16: GUIDELINES FOR MEDICAL PHYSICAL ASPECTS OF INTRAVASCULAR BRACHYTHERAPY: Evaluation of clinical results by comparison of intravascular brachytherapy treatment parameters is possible only if the prescribed dose and the applied dose distribution are reported clearly, completely and uniformly. The DGMP guidelines thus recommend to prescribe the dose to water at the system related reference point PRef at 2 mm radial distance for intracoronary application (and at 5 mm for peripheral vessels). The mean dose at 1 mm tissue depth (respectively at 2 mm) should be reported in addition. To safely define the planning target volume from the injured length, safety margins of at least 5 mm (10 mm) have to be taken into account on both ends. Safety margins have also to be considered for

  20. Trends in cochlear implants.

    Science.gov (United States)

    Zeng, Fan-Gang

    2004-01-01

    More than 60,000 people worldwide use cochlear implants as a means to restore functional hearing. Although individual performance variability is still high, an average implant user can talk on the phone in a quiet environment. Cochlear-implant research has also matured as a field, as evidenced by the exponential growth in both the patient population and scientific publication. The present report examines current issues related to audiologic, clinical, engineering, anatomic, and physiologic aspects of cochlear implants, focusing on their psychophysical, speech, music, and cognitive performance. This report also forecasts clinical and research trends related to presurgical evaluation, fitting protocols, signal processing, and postsurgical rehabilitation in cochlear implants. Finally, a future landscape in amplification is presented that requires a unique, yet complementary, contribution from hearing aids, middle ear implants, and cochlear implants to achieve a total solution to the entire spectrum of hearing loss treatment and management.

  1. Benefits and Risks of Cochlear Implants

    Science.gov (United States)

    ... and Medical Procedures Implants and Prosthetics Cochlear Implants Benefits and Risks of Cochlear Implants Share Tweet Linkedin ... the Use of Cochlear Implants What are the Benefits of Cochlear Implants? For people with implants: Hearing ...

  2. Reduction of exit-site infections of tunnelled intravascular catheters among neutropenic patients by sustained-release chlorhexidine dressings: results from a prospective randomized controlled trial.

    Science.gov (United States)

    Chambers, S T; Sanders, J; Patton, W N; Ganly, P; Birch, M; Crump, J A; Spearing, R L

    2005-09-01

    Exit-site and tunnel infections of tunnelled central intravascular catheters are a frequent source of morbidity among neutropenic patients and may necessitate catheter removal. They require antimicrobial therapy that increases healthcare costs and is associated with adverse drug reactions. A prospective randomized clinical trial was conducted among adult patients undergoing chemotherapy in a haematology unit. Tunnelled intravascular catheters were randomized to receive the control of a standard dressing regimen as recommended by the British Committee for Standards in Haematology, or to receive the intervention of a sustained-release chlorhexidine dressing. Follow-up data were available in 112 of 114 tunnelled intravascular catheters which were randomized. Exit-site or combined exit-site/tunnel infections occurred in 23 (43%) of 54 catheters in the control group, and five (9%) of 58 catheters in the intervention group [odds ratio (OR) for intervention group compared with control group =0.13, 95% confidence intervals (CI) 0.04-0.37, P<0.001]. More tunnelled intravascular catheters were prematurely removed from the control group than the intervention group for documented infections [20/54 (37%) vs 6/58 (10%), OR=0.20, 95%CI 0.53-0.07]. However, there was no difference in the numbers of tunnelled intravascular catheters removed for all proven and suspected intravascular catheter-related infections [21/54 (39%) vs 19/58 (33%)], or in the time to removal of catheters for any reason other than death or end of treatment for underlying disease. Thus chlorhexidine dressings reduced the incidence of exit-site/tunnel infections of indwelling tunnelled intravascular catheters without prolonging catheter survival in neutropenic patients, and could be considered as part of the routine management of indwelling tunnelled intravascular catheters among neutropenic patients.

  3. Specific features of a neonatal period in infants following intrauterine intravascular blood transfusion for fetal hemolytic disease

    Directory of Open Access Journals (Sweden)

    A. V. Ivanova

    2015-01-01

    Full Text Available The paper gives data on the characteristics of a neonatal period in infants following intrauterine blood transfusion for Rh-induced fetal hemolytic disease. It is shown that the early diagnosis and detection of the signs of fetal hemolytic disease, and intrauterine intravascular blood transfusion may prolong pregnancy, ensure the birth of a baby with normal anthropometric indicators, optimize his/her neonatal period and prognosis of severe hemolytic disease in the fetus and newborn.

  4. Lumen and calcium characteristics within calcified coronary lesions. Comparison of computed tomography coronary angiography versus intravascular ultrasound

    OpenAIRE

    Noll, Dariusz; Kruk, Mariusz; Pręgowski, Jerzy; Kaczmarska, Edyta; Kryczka, Karolina; Pracoń, Radosław; Skwarek, Mirosław; Dzielińska, Zofia; Petryka, Joanna; Śpiewak, Mateusz; Lubiszewska, Barbara; Norwa-Otto, Bożena; Opolski, Maksymilian; Witkowski, Adam; Demkow, Marcin

    2013-01-01

    Introduction Computed tomography coronary angiography (CTCA) is a diagnostic method used for exclusion of coronary artery disease. However, lower accuracy of CTCA in assessment of calcified lesions is a significant factor impeding applicability of CTCA for assessment of coronary atherosclerosis. Aim To provide insight into lumen and calcium characteristics assessed with CTCA, we compared these parameters to the reference of intravascular ultrasound (IVUS). Material and methods Two hundred and...

  5. Percepção de autoinstilação de gotas oculares em idosos com ou sem dispositivo de apoio facial

    Directory of Open Access Journals (Sweden)

    Arlindo Jose Freire Portes

    Full Text Available RESUMO Objetivo: Determinar o grau de dificuldade para instilação tópica ocular em idosos, com ou sem o auxílio de dispositivo de apoio facial, por meio de questionário. Observar qual método foi tecnicamente melhor para aplicação tópica ocular de gotas. Métodos: O estudo foi um ensaio clínico, controlado, randomizado e pareado, realizado em 50 pacientes idosos de setembro de 2015 a junho de 2016 na Policlínica Ronaldo Gazolla, Lapa-Rio de Janeiro. Um frasco de colírio Optive® foi acoplado ao dispositivo de apoio facial denominado Eyedrop®. Cada participante instilou o colírio com ou sem o auxílio do dispositivo em cada um dos olhos, sendo que a seleção ocular foi feita aleatoriamente. Foi perguntado ao paciente questões pré-formuladas sobre a dificuldade de ambos os métodos e a técnica de administração tópica ocular foi avaliada. Resultados: A instilação de gotas foi considerada difícil ou muito difícil por 10% dos idosos com o auxílio do dispositivo e por 36% sem o auxílio (p = 0,0047. Houve toque da ponta do colírio com os tecidos oculares em 64% dos pacientes que não usaram o Eyedrop® e em 4% dos que o utilizaram (p=0,000001. A maior dificuldade descrita na instilação tradicional foi acertar o olho com a gota (32% e com o dispositivo de apoio foi entender seu uso(4%. Conclusão: A maioria dos idosos instila colírios erroneamente, tocando a ponta do frasco em tecidos oculares, o que favorece sua contaminação. O dispositivo de apoio facial tornou mais segura e fácil a instilação.

  6. Intravascular enhancement with identical iodine delivery rate using different iodine contrast media in a circulation phantom.

    Science.gov (United States)

    Mihl, Casper; Wildberger, Joachim E; Jurencak, Tomas; Yanniello, Michael J; Nijssen, Estelle C; Kalafut, John F; Nalbantov, Georgi; Mühlenbruch, Georg; Behrendt, Florian F; Das, Marco

    2013-11-01

    Both iodine delivery rate (IDR) and iodine concentration are decisive factors for vascular enhancement in computed tomographic angiography. It is unclear, however, whether the use of high-iodine concentration contrast media is beneficial to lower iodine concentrations when IDR is kept identical. This study evaluates the effect of using different iodine concentrations on intravascular attenuation in a circulation phantom while maintaining a constant IDR. A circulation phantom with a low-pressure venous compartment and a high-pressure arterial compartment simulating physiological circulation parameters was used (heart rate, 60 beats per minute; stroke volume, 60 mL; blood pressure, 120/80 mm Hg). Maintaining a constant IDR (2.0 g/s) and a constant total iodine load (20 g), prewarmed (37°C) contrast media with differing iodine concentrations (240-400 mg/mL) were injected into the phantom using a double-headed power injector. Serial computed tomographic scans at the level of the ascending aorta (AA), the descending aorta (DA), and the left main coronary artery (LM) were obtained. Total amount of contrast volume (milliliters), iodine delivery (grams of iodine), peak flow rate (milliliter per second), and intravascular pressure (pounds per square inch) were monitored using a dedicated data acquisition program. Attenuation values in the AA, the DA, and the LM were constantly measured (Hounsfield unit [HU]). In addition, time-enhancement curves, aortic peak enhancement, and time to peak were determined. All contrast injection protocols resulted in similar attenuation values: the AA (516 [11] to 531 [37] HU), the DA (514 [17] to 531 [32] HU), and the LM (490 [10] to 507 [17] HU). No significant differences were found between the AA, the DA, and the LM for either peak enhancement (all P > 0.05) or mean time to peak (AA, 19.4 [0.58] to 20.1 [1.05] seconds; DA, 21.1 [1.0] to 21.4 [1.15] seconds; LM, 19.8 [0.58] to 20.1 [1.05] seconds). This phantom study demonstrates that

  7. Efficacy of alfaxalone for intravascular anesthesia and euthanasia in blue crabs (Callinectes sapidus).

    Science.gov (United States)

    Minter, Larry J; Harms, Craig A; Archibald, Kate E; Broadhurst, Heather; Bailey, Kate M; Christiansen, Emily F; Lewbart, Gregory A; Posner, Lysa P

    2013-09-01

    The objective of this study was to characterize the behavioral effects and changes in heart rate of four doses of alfaxalone delivered by intravascular injection to blue crabs (Callinectes sapidus). Thirty (male, n = 27; female, n = 3) blue crabs were randomly assigned to one of four treatment groups of alfaxalone: eight animals were assigned to each of the 5-, 10-, and 15-mg/kg treatment groups, and the remaining six animals were assigned to the 100-mg/kg group. Times for anesthetic induction and recovery periods were recorded. Righting reflex, defensive posturing, and heart rate were evaluated before, during, and after the anesthetic trial. Anesthesia was induced in all 14 animals consolidated into the high-dosage group (15 mg/kg [n = 8] and 100 mg/kg [n = 6]), which was significantly greater than 8 of 16 animals in the low-dosage group (5 mg/kg [n = 2] and 10 mg/kg [n = 6]). Median anesthesia induction time for all crabs was 0.4 min, with no significant difference in induction time between groups observed. Median recovery time was 9.4 min (n = 2), 6.1 min (n = 5), 11.3 min (n = 8), and 66.1 min (n = 5) for the 5-, 10-, 15-, and 100-mg/kg groups, respectively. Recovery times were significantly longer for crabs exposed to an induction dose of 100 mg/kg compared with the 10- and 15-mg/kg induction doses. A significant decrease in the median heart rate was observed between the baseline value and that observed at both induction and 5 min postinjection in the 100-mg/kg dose trial. Two mortalities were observed during the anesthesia trials (n = 1, 10 mg/kg; n = 1, 100 mg/kg), both associated with the autotomization of limbs. In summary, the intravascular administration of alfaxalone at 15 mg/kg provided rapid and reliable sedation, whereas alfaxalone administered at 100 mg/kg produced rapid and long lasting anesthesia.

  8. Intravascular near-infrared fluorescence molecular imaging of atherosclerosis: toward coronary arterial visualization of biologically high-risk plaques

    Science.gov (United States)

    Calfon, Marcella A.; Vinegoni, Claudio; Ntziachristos, Vasilis; Jaffer, Farouc A.

    2010-01-01

    New imaging methods are urgently needed to identify high-risk atherosclerotic lesions prior to the onset of myocardial infarction, stroke, and ischemic limbs. Molecular imaging offers a new approach to visualize key biological features that characterize high-risk plaques associated with cardiovascular events. While substantial progress has been realized in clinical molecular imaging of plaques in larger arterial vessels (carotid, aorta, iliac), there remains a compelling, unmet need to develop molecular imaging strategies targeted to high-risk plaques in human coronary arteries. We present recent developments in intravascular near-IR fluorescence catheter-based strategies for in vivo detection of plaque inflammation in coronary-sized arteries. In particular, the biological, light transmission, imaging agent, and engineering principles that underlie a new intravascular near-IR fluorescence sensing method are discussed. Intravascular near-IR fluorescence catheters appear highly translatable to the cardiac catheterization laboratory, and thus may offer a new in vivo method to detect high-risk coronary plaques and to assess novel atherosclerosis biologics.

  9. Pacemaker Implants in Children and Adolescents with Chagas Disease in Brazil: 18-Year Incidence.

    Science.gov (United States)

    Mizzaci, Carolina Christianini; Souza, Thiago Gonçalves Schroder E; Targueta, Gabriel Pelegrineti; Tótora, Ana Paula Frederico; Mateos, Juan Carlos Pachón; Mateos, José Carlos Pachon

    2017-06-01

    ções coletadas pelo Registro Brasileiro de Marca-passo. As variáveis analisadas foram: ano do implante, localidade, idade, sexo, grupo étnico dos pacientes; classificação funcional e os principais achados eletrocardiográficos de base. Em um total de 183 123 implantes realizados entre 1994 e 2011, foram identificados 214 implantes de dispositivos de estimulação cardíaca em portadores de doença de Chagas com idade inferior a 18 anos. A média de idade no momento do implante foi de 5,6 ± 6,2 anos. Bloqueios atrioventriculares de 2º e 3º graus foram responsáveis por 71% das indicações. Dos procedimentos, 55,6% foram realizados na região sudeste. Em relação ao total de implantes de marca-passo por ano, observamos um aumento importante e significante de implante por todas as causas. Entretanto, quando avaliamos a série temporal de implantes em pacientes com doença de Chagas menores que 18 anos, observamos uma redução expressiva e significativa no número anual de implantes. Observa-se uma redução importante do número de implantes de marca-passo em crianças e adolescente chagásicos, o que sugere uma redução da transmissão vertical do parasita.

  10. Optical effects of ion implantation

    International Nuclear Information System (INIS)

    Townsend, P.D.

    1987-01-01

    The review concerns the effects of ion implantation that specifically relate to the optical properties of insulators. Topics which are reviewed include: ion implantation, ion range and damage distributions, colour centre production by ion implantation, high dose ion implantation, and applications for integrated optics. Numerous examples are presented of both diagnostic and industrial examples of ion implantation effects in insulators. (U.K.)

  11. Ion implantation in semiconductors

    International Nuclear Information System (INIS)

    Gusev, V.; Gusevova, M.

    1980-01-01

    The historical development is described of the method of ion implantation, the physical research of the method, its technological solution and practical uses. The method is universally applicable, allows the implantation of arbitrary atoms to an arbitrary material, ensures high purity of the doping element. It is linked with sample processing at low temperatures. In implantation it is possible to independently change the dose and energy of the ions thereby affecting the spatial distribution of the ions. (M.S.)

  12. Ion implantation in semiconductors

    Energy Technology Data Exchange (ETDEWEB)

    Gusev, V; Gusevova, M

    1980-06-01

    The historical development of the method of ion implantation, the physical research of the method, its technological solution and practical uses is described. The method is universally applicable, allows the implantation of arbitrary atoms to an arbitrary material and ensures high purity of the doping element. It is linked with sample processing at low temperatures. In implantation it is possible to independently change the dose and energy of the ions thereby affecting the spatial distribution of the ions.

  13. Trends in Cochlear Implants

    OpenAIRE

    Zeng, Fan-Gang

    2004-01-01

    More than 60,000 people worldwide use cochlear implants as a means to restore functional hearing. Although individual performance variability is still high, an average implant user can talk on the phone in a quiet environment. Cochlear-implant research has also matured as a field, as evidenced by the exponential growth in both the patient population and scientific publication. The present report examines current issues related to audiologic, clinical, engineering, anatomic, and physiologic as...

  14. Ion implantation technology

    CERN Document Server

    Downey, DF; Jones, KS; Ryding, G

    1993-01-01

    Ion implantation technology has made a major contribution to the dramatic advances in integrated circuit technology since the early 1970's. The ever-present need for accurate models in ion implanted species will become absolutely vital in the future due to shrinking feature sizes. Successful wide application of ion implantation, as well as exploitation of newly identified opportunities, will require the development of comprehensive implant models. The 141 papers (including 24 invited papers) in this volume address the most recent developments in this field. New structures and possible approach

  15. High energy ion implantation

    International Nuclear Information System (INIS)

    Ziegler, J.F.

    1985-01-01

    High energy ion implantation offers the oppertunity for unique structures in semiconductor processing. The unusual physical properties of such implantations are discussed as well as the special problems in masking and damage annealing. A review is made of proposed circuit structures which involve deep implantation. Examples are: deep buried bipolar collectors fabricated without epitaxy, barrier layers to reduce FET memory sensitivity to soft-fails, CMOS isolation well structures, MeV implantation for customization and correction of completed circuits, and graded reach-throughs to deep active device components. (orig.)

  16. [Silastic implant and synovitis].

    Science.gov (United States)

    Sennwald, G

    1989-07-22

    The silastic implant based on siloxane polymere induces granulomatous synovitis in certain predisposed individuals, a reaction which may continue even after removal of the implant. This is also true of a prosthesis of the trapezium in two of our patients, though to a lesser degree. This is probably the reason why the problem has not yet been widely recognized. The hypothesis is put forward that an enzymatic predisposition may allow chemical degradation of the fragmented silastic implant into a toxic component responsible for the pathologic condition. The slow progression of the lesions is a challenge for the future and puts in question the further use of silastic implants.

  17. Cochlear implant magnet retrofit.

    Science.gov (United States)

    Cohen, N L; Breda, S D; Hoffman, R A

    1988-06-01

    An implantable magnet is now available for patients who have received the standard Nucleus 22-channel cochlear implant and who are not able to wear the headband satisfactorily. This magnet is attached in piggy-back fashion to the previously implanted receiver/stimulator by means of a brief operation under local anesthesia. Two patients have received this magnet retrofit, and are now wearing the headset with greater comfort and satisfaction. It is felt that the availability of this magnet will increase patient compliance in regard to hours of implant usage.

  18. Intravascular Immune Surveillance by CXCR6+ NKT Cells Patrolling Liver Sinusoids

    Directory of Open Access Journals (Sweden)

    Geissmann Frederic

    2005-01-01

    Full Text Available We examined the in vivo behavior of liver natural killer T cells (NKT cells by intravital fluorescence microscopic imaging of mice in which a green fluorescent protein cDNA was used to replace the gene encoding the chemokine receptor CXCR6. NKT cells, which account for most CXCR6+ cells in liver, were found to crawl within hepatic sinusoids at 10-20 µm/min and to stop upon T cell antigen receptor activation. CXCR6-deficient mice exhibited a selective and severe reduction of CD1d-reactive NKT cells in the liver and decreased susceptibility to T-cell-dependent hepatitis. CXCL16, the cell surface ligand for CXCR6, is expressed on sinusoidal endothelial cells, and CXCR6 deficiency resulted in reduced survival, but not in altered speed or pattern of patrolling of NKT cells. Thus, NKT cells patrol liver sinusoids to provide intravascular immune surveillance, and CXCR6 contributes to liver-based immune responses by regulating their abundance.

  19. Orbital Atherectomy Plaque Modification Assessment of the Femoropopliteal Artery Via Intravascular Ultrasound (TRUTH Study).

    Science.gov (United States)

    Babaev, Anvar; Zavlunova, Susanna; Attubato, Michael J; Martinsen, Brad J; Mintz, Gary S; Maehara, Akiko

    2015-10-01

    The Tissue Removal Assessment with Ultrasound of the SFA and Popliteal (TRUTH) study assessed the performance of the orbital atherectomy system (OAS) to treat femoropopliteal arteries, including determining its effect on plaque removal. Patients with symptomatic femoropopliteal peripheral arterial disease were treated with the OAS followed by adjunctive balloon angioplasty (BA). Intravascular ultrasound (IVUS) images were collected pre- and post-OAS and post-OAS BA. Patients were followed through 12 months post-procedure. Twenty-nine lesions were treated with OAS-BA in 25 patients. The mean maximum balloon inflation pressure was 5.2 ± 1.2 atm. Virtual histology IVUS (VH-IVUS) analysis revealed at the maximum calcium ablation site that calcium reduction was responsible for 86% of the lumen area increase. The minimum lumen area increased from 4.0 mm(2) to 9.1 mm(2) (<.0001), and the percentage of area stenosis decreased from 76.9% to 43.0% (<.0001) after OAS-BA. At 12 months, the target lesion revascularization rate was 8.2%, and ankle-brachial index and Rutherford classification improved significantly from baseline through follow-up. The VH-IVUS analysis reveals that OAS modifies the calcified component of the plaque burden. It is hypothesized that calcium modification by OAS changes the lesion compliance, allowing for low pressure adjunctive BA. The clinical outcomes were favorable through 12-month follow-up. © The Author(s) 2015.

  20. Transcatheter Arterial Embolization for Postpartum Hemorrhage with Disseminated Intravascular Coagulation: Outcome Assessment

    Energy Technology Data Exchange (ETDEWEB)

    An, Eun Jung; Kim, Young Hwan; Kwon, Bo Ra; Kim, See Hyung [Dept. of Radiology, Dongsan Medical Center, Keimyung University College of Medicine, Daegu (Korea, Republic of)

    2011-12-15

    We evaluated the efficacy and predictors of clinical outcome after transcatheter arterial embolization (TAE) for treatment of postpartum hemorrhage with disseminated intravascular coagulation (DIC). Of 127 patients who underwent TAE for postpartum hemorrhage, 46 progressed to DIC (group 1), 81 showed normal range hematological parameters (group 2). We retrospectively evaluated etiology, embolization methods and the efficacy of TAE for intergroup comparison Pearson Chi-Square test and logistic regression model. Overall TAE failed to control bleeding in 9 patients in spite of technical success. Lower bleeding control rate was found in group 2 (82.6%) relative to group 1 (98.8%, p = 0.001). And embolization methods were not statistically different between two groups no statistically significant predictors associated with failed hemostasis except the amount of transfusion in group 1. Although bleeding control rate is lower in postpartum hemorrhage with DIC than without DIC, we believe that TAE with correction of DIC is an effective method for postpartum hemorrhage with DIC.

  1. Transcatheter Arterial Embolization for Postpartum Hemorrhage with Disseminated Intravascular Coagulation: Outcome Assessment

    International Nuclear Information System (INIS)

    An, Eun Jung; Kim, Young Hwan; Kwon, Bo Ra; Kim, See Hyung

    2011-01-01

    We evaluated the efficacy and predictors of clinical outcome after transcatheter arterial embolization (TAE) for treatment of postpartum hemorrhage with disseminated intravascular coagulation (DIC). Of 127 patients who underwent TAE for postpartum hemorrhage, 46 progressed to DIC (group 1), 81 showed normal range hematological parameters (group 2). We retrospectively evaluated etiology, embolization methods and the efficacy of TAE for intergroup comparison Pearson Chi-Square test and logistic regression model. Overall TAE failed to control bleeding in 9 patients in spite of technical success. Lower bleeding control rate was found in group 2 (82.6%) relative to group 1 (98.8%, p = 0.001). And embolization methods were not statistically different between two groups no statistically significant predictors associated with failed hemostasis except the amount of transfusion in group 1. Although bleeding control rate is lower in postpartum hemorrhage with DIC than without DIC, we believe that TAE with correction of DIC is an effective method for postpartum hemorrhage with DIC.

  2. Hyperkalemia after irradiation of packed red blood cells: Possible effects with intravascular fetal transfusion

    International Nuclear Information System (INIS)

    Thorp, J.A.; Plapp, F.V.; Cohen, G.R.; Yeast, J.D.; O'Kell, R.T.; Stephenson, S.

    1990-01-01

    Plasma potassium, calcium, and albumin concentrations in irradiated blood, and in fetal blood before and after transfusion, were measured. Dangerously high plasma potassium levels were observed in some units of irradiated packed red blood cells (range, 13.9 to 66.5 mEq/L; mean, 44.7 mEq/L) and could be one possible explanation for the high incidence of fetal arrhythmia associated with fetal intravascular transfusion. There are many factors operative in the preparation of irradiated packed red blood cells that may predispose to high potassium levels: the age of the red blood cells, the number of procedures used to concentrate the blood, the duration of time elapsed from concentration, the duration of time elapsed from irradiation, and the hematocrit. Use of fresh blood, avoidance of multiple packing procedures, limiting the hematocrit in the donor unit to less than or equal to 80%, and minimizing the time between concentration, irradiation and transfusion may minimize the potassium levels, and therefore making an additional washing procedure unnecessary

  3. The study of cardiovascular changes by intravascular injection of contrast media

    International Nuclear Information System (INIS)

    Kim, Yang Sook; Park, Chang Yoon

    1986-01-01

    This investigation was aimed to study the effect of contrast media on the cardiovascular system. So in this study, pithed rats were used whether alteration in cardiovascular system by contrast media were controlled centrally. Furthermore, several hypertonic solutions were also used to clarify the effect of contrast media. The results are as follows: 1. Intravenous injection of contrast media in rats (2.5 ml/kg) caused hypotension and bradycardia. The effects were neither blocked by pretreatment of atropine nor pyribenzamine+atropine. 2. NaCI 4.7%, dextrose 24.8%, urea 9.0% and glycerol 10.1% (v/v) which were equiosmolar with contrast media, caused hypotension, but did not affect the heart rate. 3. In pithed rats, intravenous injection of Angiografin increased blood pressure in a dose-dependant manner, and caused decrease in heart rate compared with those of control rats. 4. In pithed rats, bradycardia by intravascular injection with Angiografin was partially blocked by atropine. 5. Metrizamide of which iodine content was adjusted to 280 mg/ml caused increased in blood pressure when was injected intravenously in pithed rats with little effect on heart rate. 6. When perfused with contrast media in rat hindlimb at 15 ml/min./kg speed both perfusion pressure and flow effluent increased, simultaneously. These results suggest that hypotension might be caused by the central effect due to hyperosmolarity of contrast media and bradycardia caused by both parasympathetic stimulation and direct inhibitory action on the cardiac conductive system.

  4. Protein Z efficiently depletes thrombin generation in disseminated intravascular coagulation with poor prognosis.

    Science.gov (United States)

    Lee, Nuri; Kim, Ji-Eun; Gu, Ja-Yoon; Yoo, Hyun Ju; Kim, Inho; Yoon, Sung-Soo; Park, Seonyang; Han, Kyou-Sup; Kim, Hyun Kyung

    2016-01-01

    Disseminated intravascular coagulation (DIC) is characterized by consumption of coagulation factors and anticoagulants. Thrombin generation assay (TGA) gives useful information about global hemostatic status. We developed a new TGA system that anticoagulant addition can deplete thrombin generation in plasma, which may reflect defective anticoagulant system in DIC. TGAs were measured on the calibrated automated thrombogram with and without thrombomodulin or protein Z in 152 patients who were suspected of having DIC, yielding four parameters including lag time, endogenous thrombin potential, peak thrombin and time-to-peak in each experiment. Nonsurvivors showed significantly prolonged lag time and time-to-peak in TGA-protein Z system, which was performed with added protein Z. In multivariate Cox regression analysis, lag time and time-to-peak in TGA system were significant independent prognostic factors. In TGA-protein Z system, lag time and time-to-peak were revealed as independent prognostic factors of DIC. Protein Z addition could potentiate its anticoagulant effect in DIC with poor prognosis, suggesting the presence of defective protein Z system. The prolonged lag time and time-to-peak in both TGA and TGA-protein Z systems are expected to be used as independent prognostic factors of DIC.

  5. TWO NOVEL ACM (ACTIVE CONTOUR MODEL) METHODS FOR INTRAVASCULAR ULTRASOUND IMAGE SEGMENTATION

    International Nuclear Information System (INIS)

    Chen, Chi Hau; Potdat, Labhesh; Chittineni, Rakesh

    2010-01-01

    One of the attractive image segmentation methods is the Active Contour Model (ACM) which has been widely used in medical imaging as it always produces sub-regions with continuous boundaries. Intravascular ultrasound (IVUS) is a catheter based medical imaging technique which is used for quantitative assessment of atherosclerotic disease. Two methods of ACM realizations are presented in this paper. The gradient descent flow based on minimizing energy functional can be used for segmentation of IVUS images. However this local operation alone may not be adequate to work with the complex IVUS images. The first method presented consists of basically combining the local geodesic active contours and global region-based active contours. The advantage of combining the local and global operations is to allow curves deforming under the energy to find only significant local minima and delineate object borders despite noise, poor edge information and heterogeneous intensity profiles. Results for this algorithm are compared to standard techniques to demonstrate the method's robustness and accuracy. In the second method, the energy function is appropriately modified and minimized using a Hopfield neural network. Proper modifications in the definition of the bias of the neurons have been introduced to incorporate image characteristics. The method overcomes distortions in the expected image pattern, such as due to the presence of calcium, and employs a specialized structure of the neural network and boundary correction schemes which are based on a priori knowledge about the vessel geometry. The presented method is very fast and has been evaluated using sequences of IVUS frames.

  6. Intravascular optical imaging of high-risk plaques in vivo by targeting macrophage mannose receptors

    Science.gov (United States)

    Kim, Ji Bak; Park, Kyeongsoon; Ryu, Jiheun; Lee, Jae Joong; Lee, Min Woo; Cho, Han Saem; Nam, Hyeong Soo; Park, Ok Kyu; Song, Joon Woo; Kim, Tae Shik; Oh, Dong Joo; Gweon, Daegab; Oh, Wang-Yuhl; Yoo, Hongki; Kim, Jin Won

    2016-03-01

    Macrophages mediate atheroma expansion and disruption, and denote high-risk arterial plaques. Therefore, they are substantially gaining importance as a diagnostic imaging target for the detection of rupture-prone plaques. Here, we developed an injectable near-infrared fluorescence (NIRF) probe by chemically conjugating thiolated glycol chitosan with cholesteryl chloroformate, NIRF dye (cyanine 5.5 or 7), and maleimide-polyethylene glycol-mannose as mannose receptor binding ligands to specifically target a subset of macrophages abundant in high-risk plaques. This probe showed high affinity to mannose receptors, low toxicity, and allowed the direct visualization of plaque macrophages in murine carotid atheroma. After the scale-up of the MMR-NIRF probe, the administration of the probe facilitated in vivo intravascular imaging of plaque inflammation in coronary-sized vessels of atheromatous rabbits using a custom-built dual-modal optical coherence tomography (OCT)-NIRF catheter-based imaging system. This novel imaging approach represents a potential imaging strategy enabling the identification of high-risk plaques in vivo and holds promise for future clinical implications.

  7. Optimization of dual-wavelength intravascular photoacoustic imaging of atherosclerotic plaques using Monte Carlo optical modeling

    Science.gov (United States)

    Dana, Nicholas; Sowers, Timothy; Karpiouk, Andrei; Vanderlaan, Donald; Emelianov, Stanislav

    2017-10-01

    Coronary heart disease (the presence of coronary atherosclerotic plaques) is a significant health problem in the industrialized world. A clinical method to accurately visualize and characterize atherosclerotic plaques is needed. Intravascular photoacoustic (IVPA) imaging is being developed to fill this role, but questions remain regarding optimal imaging wavelengths. We utilized a Monte Carlo optical model to simulate IVPA excitation in coronary tissues, identifying optimal wavelengths for plaque characterization. Near-infrared wavelengths (≤1800 nm) were simulated, and single- and dual-wavelength data were analyzed for accuracy of plaque characterization. Results indicate light penetration is best in the range of 1050 to 1370 nm, where 5% residual fluence can be achieved at clinically relevant depths of ≥2 mm in arteries. Across the arterial wall, fluence may vary by over 10-fold, confounding plaque characterization. For single-wavelength results, plaque segmentation accuracy peaked at 1210 and 1720 nm, though correlation was poor (blood, a primary and secondary wavelength near 1210 and 1350 nm, respectively, may offer the best implementation of dual-wavelength IVPA imaging. These findings could guide the development of a cost-effective clinical system by highlighting optimal wavelengths and improving plaque characterization.

  8. Persistent lesion hyperintensity on brain diffusion-weighted MRI is an early sign of intravascular lymphoma.

    Science.gov (United States)

    Kageyama, Takashi; Yamanaka, Haruo; Nakamura, Fumihiko; Suenaga, Toshihiko

    2017-06-08

    A 63-year-old man presented with right-sided hemianopia and unsteady gait. Brain MRI revealed multiple hyperintense infarct-like lesions on diffusion-weighted images (DWI). Hyperintensity persisted in some of these lesions even after 6 weeks, although his symptoms were ameliorated then. The patient developed episodic dizziness and a transient event of apraxia at 18 weeks after the first episode. Brain MRI revealed additional hyperintense lesions on DWI, which persisted even after 7 weeks. Eventually, the patient manifested cauda equina syndrome 39 weeks after the first episode. Brain MRI showed the presence of new lesions in addition to the persistent hyperintense lesions on DWI over 21 weeks in the right frontal lobe. Based on laboratory findings and the pathological assessment of bone marrow and random skin biopsies, the patient was diagnosed with intravascular lymphoma (IVL). Persistent hyperintense lesions on DWI of brain MRI may precede the clinical exacerbation of IVL. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  9. Risk of disseminated intravascular coagulation in patients undergoing US-guided transperineal prostatic biopsy

    International Nuclear Information System (INIS)

    Stella, M.S.; Comparato, D.; Camici, M.; Evangelisti, L.; Gaudio, V.; De Negri, F.; Talarico, L.; Giusti, C.; Morelli, G.

    1991-01-01

    Disseminated intravascular coagulation (DIC) is a severe life-threatening acute bleeding disorder. Traumatized tissues, tumors, necrotic tissues, or bacterial endotoxines release similar material in the blood to the tissutal factors activating the coagulation cascade. This preliminary study was aimed at verifying the risk of DIV in patients undergoing US-guided transperineal prostatic biopsy with Chiba and Tru-Cut needles. To evaluate the activation degree of coagulation factors in the circulation, the authors measured the concentrations of urinary fibrin degradation products in 10 patients undergoing US-guided transperineal prostatic biopsy, both before and after biopsy, every second hour, for 24 hours. Every tube of urine sample contained soya bean trypsin inhibitor and bovine thrombin to prevent any further fibrin degradation during incubation period for the possible presence of blood in urine samples. The results showed that 7/10 patients had marked increase in urinary fibrin degradation product levels (up to 800 XXXX%), with a 3-phase trend: early peak after 2-6 hours, middle peak after 6-14 hours, and late peak after 18-24 hours, which proved the activation of the coagulation cascade

  10. CT virtual intravascular endoscopy assessment of coronary artery plaques: A preliminary study

    International Nuclear Information System (INIS)

    Sun Zhonghua; Dimpudus, Franky Jacobus; Nugroho, Johanes; Adipranoto, Jeffrey Daniel

    2010-01-01

    Purpose: The purpose of this study was to investigate the potential value of CT virtual intravascular endoscopy (VIE) in the visualization and assessment of coronary plaques in patients suspected of coronary artery disease. Materials and methods: 20 (13 men, 7 women, mean age 54 years) consecutive patients with suspected coronary artery disease undergoing 64-slice CT angiography were included in the study. Four main coronary artery branches were assessed with regard to the presence of coronary plaques based on 2D axial, multiplanar reformation, 3D volume rendering and VIE visualizations. The coronary plaques were characterized into calcified, noncalcified and mixed plaques. The intraluminal appearances of these coronary plaques were demonstrated with VIE images and correlated with 2D and 3D images to determine the diagnostic value of VIE for the assessment of the plaques. Results: VIE was able to identify and demonstrate the intraluminal appearances of coronary plaques in 18 patients involving 32 coronary artery branches which were shown as an irregularly intraluminal protruding sign in extensively calcified plaques and smooth protruding appearance in noncalcified or focally calcified plaques. An irregular intraluminal appearance was also noticed in the presence of mixed plaques due to variable components with different CT attenuations contained within the plaques. VIE accurately confirmed the degree of coronary stenosis or occlusion despite the presence of heavy calcification. Conclusion: VIE could be used as a complementary tool to conventional CT visualizations for the analysis of luminal changes and assessment of disease extent caused by the coronary plaques.

  11. Indium-111-oxine labeled platelet scintigraphy for detection of intracardiac and intravascular thrombi

    Energy Technology Data Exchange (ETDEWEB)

    Kimura, Michio; Ojima, Kenji; Tsuda, Takashi [Niigata Univ. (Japan). School of Medicine

    1983-09-01

    This study was designed to evaluate the efficacy of scintigraphy by using /sup 111/In-oxine labeled platelets for the detection of either intracardiac or intravascular thrombi. Fourteen cases of thrombi diagnosed or suspected on the basis of either angiography or two-dimensional echography were examined. They included four cases of left ventricular thrombi, three of left atrial thrombi, four of vascular thrombi and three of inflammatory disease. Platelet samples from the patients were labeled by /sup 111/In-oxine according to the method originated by Yui et al. The labeling efficiency was 72.4+-9.8%. The platelets retained good function except for collagen aggregability. Hot areas of high quality in the scintigram were demonstrated in six cases including two with left ventricular thrombi, two with left atrial thrombi and two with vascular thrombi. These areas accorded well with the findings of angiography, echography or surgery. The removed thrombi had a layer of aggregated platelets on the surface. Platelet survival was shortened in a case of prosthetic valve endocarditis without a hot area, and was normal in four out of the five cases including two with a hot area. It is concluded that this method is potentially predictive in detecting thrombi.

  12. Development of an intravascular ultrasound elastography based on a dual-element transducer

    Science.gov (United States)

    Shih, Cho-Chiang; Chen, Pei-Yu; Ma, Teng; Zhou, Qifa; Shung, K. Kirk; Huang, Chih-Chung

    2018-04-01

    The ability to measure the elastic properties of plaques and vessels would be useful in clinical diagnoses, particularly for detecting a vulnerable plaque. This study demonstrates the feasibility of the combination of intravascular ultrasound (IVUS) and acoustic radiation force elasticity imaging for detecting the distribution of stiffness within atherosclerotic arteries ex vivo. A dual-frequency IVUS transducer with two elements was used to induce the propagation of the shear wave (by the 8.5 MHz pushing element) which could be simultaneously monitored by the 31 MHz imaging element. The wave-amplitude image and the wave-velocity image were reconstructed by measuring the peak displacement and wave velocity of shear wave propagation, respectively. System performance was verified using gelatin phantoms. The phantom results demonstrate that the stiffness differences of shear modulus of 1.6 kPa can be distinguished through the wave-amplitude and wave-velocity images. The stiffness distributions of the atherosclerotic aorta from a rabbit were obtained, for which the values of peak displacement and the shear wave velocity were 3.7 ± 1.2 µm and 0.38 ± 0.19 m s-1 for the lipid-rich plaques, and 1.0 ± 0.2 µm and 3.45 ± 0.45 m s-1 for the arterial walls, respectively. These results indicate that IVUS elasticity imaging can be used to distinguish the elastic properties of plaques and vessels.

  13. Intravascular application of electrocautery in a rabbit model of abdominal aortic endarterectomy.

    Science.gov (United States)

    Wang, Chuan; Xin, Yi; Li, Na; Li, Diankun; Li, Jingxing; Gu, Chengxiong

    2017-07-01

    Effective therapies for preventing perioperative complications such as thrombosis and inflammation after coronary endarterectomy (CE) are lacking. Electrocoagulation electrotomes have been routinely used in surgery for their cutting, clotting, and hemostatic properties. As strong flattening tools, their electrocautery function may prevent mechanical intimal-adventitial injury to arterial circulation and attenuate stenosis. The present study investigated the effects of intravascular application of electrocautery on ameliorating inflammation and thrombosis in a rabbit model of abdominal aortic endarterectomy. New Zealand rabbits were randomly divided into the sham, control (endarterectomy), and study (endarterectomy + electrocautery) groups with 10 in each group. Abdominal aortas were partially blocked and intima was removed. Electrocautery was performed with an electrocoagulation electrotome through the entire blocked vessel lumen. Vascular ultrasound parameters, molecular biological and histological characteristics of the abdominal aorta including vascular diameter, blood flow velocity, serum interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) levels, and apoptosis rate of vascular endothelial cells (ECs) were evaluated postoperatively by vascular Doppler ultrasound, ELISA, real-time RT-PCR, flow cytometry, and immunofluorescence at various time points. Compared with the endarterectomy + electrocautery group, the isolated endarterectomy group had significantly increased levels and gene expression of TNF-α and IL-6 (Pelectrocautery has favorable short-term effects on the abdominal aorta and can reduce inflammation in a rabbit model of abdominal aorta endarterectomy. Long-term anti-inflammatory and anti-thrombotic effects on arterial remodeling and the clinical value of electrocautery in CE remain to be determined.

  14. Validating Intravascular Imaging with Serial Optical Coherence Tomography and Confocal Fluorescence Microscopy.

    Science.gov (United States)

    Tardif, Pier-Luc; Bertrand, Marie-Jeanne; Abran, Maxime; Castonguay, Alexandre; Lefebvre, Joël; Stähli, Barbara E; Merlet, Nolwenn; Mihalache-Avram, Teodora; Geoffroy, Pascale; Mecteau, Mélanie; Busseuil, David; Ni, Feng; Abulrob, Abedelnasser; Rhéaume, Éric; L'Allier, Philippe; Tardif, Jean-Claude; Lesage, Frédéric

    2016-12-15

    Atherosclerotic cardiovascular diseases are characterized by the formation of a plaque in the arterial wall. Intravascular ultrasound (IVUS) provides high-resolution images allowing delineation of atherosclerotic plaques. When combined with near infrared fluorescence (NIRF), the plaque can also be studied at a molecular level with a large variety of biomarkers. In this work, we present a system enabling automated volumetric histology imaging of excised aortas that can spatially correlate results with combined IVUS/NIRF imaging of lipid-rich atheroma in cholesterol-fed rabbits. Pullbacks in the rabbit aortas were performed with a dual modality IVUS/NIRF catheter developed by our group. Ex vivo three-dimensional (3D) histology was performed combining optical coherence tomography (OCT) and confocal fluorescence microscopy, providing high-resolution anatomical and molecular information, respectively, to validate in vivo findings. The microscope was combined with a serial slicer allowing for the imaging of the whole vessel automatically. Colocalization of in vivo and ex vivo results is demonstrated. Slices can then be recovered to be tested in conventional histology.

  15. Reversible Hypopituitarism Associated with Intravascular Large B-Cell Lymphoma: Case Report of Successful Immunochemotherapy.

    Science.gov (United States)

    Sawada, Yusuke; Ishii, Sumiyasu; Koga, Yasuhiko; Tomizawa, Taku; Matsui, Ayako; Tomaru, Takuya; Ozawa, Atsushi; Shibusawa, Nobuyuki; Satoh, Tetsurou; Shimizu, Hiroaki; Hirato, Junko; Yamada, Masanobu

    2016-03-01

    Intravascular large B-cell lymphoma (IVLBCL) is a rare subtype of diffuse large B-cell lymphoma. There have been only a limited number of reports regarding pituitary dysfunction associated with IVLBCL. We present a 71-year-old woman with hypopituitarism without any hypothalamic/pituitary abnormalities as assessed by magnetic resonance imaging. She presented with edema, abducens palsy, and elevated levels of lactate dehydrogenase and soluble interleukin-2 receptor. Provocative testing showed that the peaks of luteinizing hormone, follicle-stimulating hormone, thyroid-stimulating hormone and adrenocorticotropic hormone were evoked to normal levels by simultaneous administration of luteinizing hormone-releasing hormone, thyrotropin-releasing hormone and corticotropin-releasing hormone, but the responses of these four pituitary hormones showed a delayed pattern. She was diagnosed with IVLBCL with cerebrospinal invasion by pathological findings of the bone marrow, skin, and cerebrospinal fluid. She achieved hematological remission after immunochemotherapy. Pituitary function was also restored without hormonal replacement, and the improvement of the pituitary function was confirmed by dynamic testing. We reviewed the literature with respect to hypopituitarism associated with IVLBCL. There were less than 20 case reports and most of the patients died. Endocrinological course was described in only two cases, and both of them required hormonal supplementation. To our knowledge, this is the first case of hypopituitarism induced by IVLBCL that was successfully managed by immunochemotherapy alone. This case suggests that early diagnosis and treatment of IVLBCL might improve anterior pituitary function and enable patients to avoid hormone replacement therapy.

  16. Monte Carlo dosimetry of a tandem positioned beta-emitting intravascular brachytherapy source train

    International Nuclear Information System (INIS)

    Wallace, Steven A.; Schumer, Wendy; Horrigan, Mark

    2002-01-01

    Prevention of restenosis following interventional coronary procedures with catheter based beta-emitting sources is currently under clinical trial investigations. Systems utilizing fixed length source trains limit the clinician's ability to increase the radiation source length as required. A technique known as 'pull back' is used when the segment of artery requiring radiation is longer than the available fixed length source train. In this instance, tandem positioning of the fixed length source is used to treat the longer length of artery. The aim of this study was to examine the dosimetry of the junction region associated with pull back treatments using a commercially available 90 Sr/Y catheter based intravascular brachytherapy source train. Dose profiles were calculated, using the Monte Carlo code MCNP4B, at radial distances of 1.5, 2.0, and 2.5 mm for pull back techniques using 2.5 mm overlapping, abutting, and 2.5 mm spaced source trains. Results at the protocol prescription radius of 2 mm showed a junction dose elevated 61% above prescription for 2.5 mm overlapping source trains. For 2.5 mm spaced trains, this figure falls to 64% below prescription dose. In contrast, abutted source trains exhibited only a 1% depression below prescription dose in the junction region. The reference point dose rate per unit activity of this source was found to be consistent with previous studies

  17. Dispositivo óptico para medida em tempo real da birrefringência de polímeros durante a extrusão

    OpenAIRE

    Kinglston Soares

    2010-01-01

    Este projeto teve como principais objetivos o desenvolvimento e aplicação de um dispositivo óptico para medida em tempo real da birrefringência induzida por fluxo durante a extrusão de polímeros. O princípio consiste em medir a intensidade de luz linearmente polarizada transmitida através do polímero sob fluxo e converter este sinal em birrefringência por meio da relação com a diferença de caminho óptico (OPD). O dispositivo óptico foi aferido em bancada com o uso de placas de policarbonato c...

  18. System for Comparing Gamma Sources Varying by Ratios of up to 1:1000; Dispositivo Gamma que para Comparar Fuentes Difieren Hasta uno En Mil

    Energy Technology Data Exchange (ETDEWEB)

    Tejera Rivera, A.; Navarro Cuevas, D. [Universidad Nacional Autonoma de Mexico, Mexico D.F. (Mexico)

    1967-03-15

    Two nonelectronic devices have been constructed permitting continuous and reasonably accurate amplification by a factor of up to 100 of the counting capacity of a scintillation system. This system is designed for use in comparing the activities of radiation sources, mainly of the gamma type, and also the activities of one and the same radioisotope, when they differ by a ratio of the order 1:1000. The immediate use of the system is in the preparation of gamma standards for the calibration of ionization chambers requiring radioisotope (e. g. {sup 60}Co and {sup 131}I) activities in millicuries, on the basis of corresponding standards with activities of the order of microcuries. The basic principle involved is to limit the passage of light through the scintillation crystal to the photomultiplier tube. In the first device, half the face of the Nal(Tl) scintillation crystal and half the face of the photomultiplier are screened in such a way that rotation of the crystal causes the screens to be superimposed and the amount of light is cut down by from 50% to nil. With this device, it has been possible in practice to compare activities varying by 1:20. The second device is fitted with five diaphragms on a rotating disk which permit the passage of light to be regulated from 100% to nil. Using this device, it is possible to compare sources varying in activity by ratios of up to 1:1000, keeping the scaler reading within the limits of 100 000 counts/min. The main advantage to this procedure is that error due to differences in counter dead time for counts on sources varying widely in activity is reduced; further, samples of this kind can be compared using small-size shielding. (author) [Spanish] Se han construido dos dispositivos no electronicos que permiten ampliar hasta 100 veces, de manera continua y con buena exactitud, la capacidad de recuento de un equipo de centelleo. La finalidad de este dispositivo es la comparacion de las actividades de fuentes de radiacion

  19. DECODIFICANDO MI FLORA Uso de dispositivos móviles y tablets en educación

    Directory of Open Access Journals (Sweden)

    Arnulfo Estrada M

    2014-05-01

    Full Text Available Los códigos QR (códigos de barras de rápida respuesta en la actualidad son una forma de compartir información de manera visual accediendo a ella por medio de dispositivos móviles y tablets tan solo con apuntar la cámara hacia el código;  muy utilizado por empresas, agencias de publicidad, supermercados etc. El uso de estas tecnologías que están en todos lados, permite, en este caso, que los estudiantes puedan acceder a contenidos digitales educativos que complementan su aprendizaje, que fuera de este contexto podrían parecer irrelevantes. Por tal razón el presente trabajo muestra ambientes de aprendizaje basados en tecnología móvil, mediante la codificación QR de la información más relevante de la flora encontrada en el Centro Ambiental las Iguanas de Montería, con el fin de darla a conocer accediendo a su información mediante el uso de dispositivos móviles, buscando así, su extrapolación a la Ronda del Sinú. Para ello se consultó la información de cada árbol escogido para luego ser incorporada como narración en los videos creados con fotos de cada planta; los videos editados se subieron a internet para obtener su URL respectiva y así generar los códigos QR correspondientes; estos códigos fueron impresos en acrílico y pegados a cada planta para así acceder a su información. Con este trabajo se ha logrado por parte delos estudiantes, la apropiación de las competencias científicas, comunicativas, ciudadanas y tecnológicas (MTICs, incentivación al Desarrollo Sostenible y recuperar información de la tradición oral que tienen nuestros abuelos acerca de estos árboles.

  20. Ver, Compreender e Aprender: estudo comparado com guias de uso de apps editoriais para dispositivos móveis

    Directory of Open Access Journals (Sweden)

    Ana Claudia Dalagnoli

    2016-12-01

    Full Text Available Este estudo foi construído a partir da percepção de que a evolução das tecnologias e, sobretudo, o aprimoramento da comunicação em dispositivos móveis, impacta diretamente no processo de desenvolvimento de aplicativos (apps e softwares e na relação do ser humano com as novas interfaces. A pesquisa apresenta uma análise comparativa entre os aplicativos para iPad das revistas de decoração e design de interiores Casa Claudia (Editora Abril e Casa e Jardim (Editora Globo, a partir de testes de usabilidade dos mesmos em tablets Apple. O objetivo foi verificar se os guias de uso disponíveis em aplicativos (apps de revistas para dispositivos móveis, construídos por textos e imagens, estão cumprindo a função de comunicar, efetivamente, o modo de uso desses apps. As informações foram coletadas junto a mulheres com idade entre 25 e 54 anos que testaram e comentaram o funcionamento das versões atuais dos apps. Foram selecionadas 24 mulheres para fazerem atividades individuais monitoradas em ambos os apps, com dados coletados por meio de observações e think aloud. Os dados obtidos foram analisados, e com base nos resultados foi proposto um ajuste nos requisitos para o desenvolvimento de interfaces de guias para aplicativos com vistas à maior satisfação das usuárias. Foram percebidas falhas severas na apreensão e aplicação das orientações disponíveis nos guias de uso. Os pesquisadores verificaram que os requisitos básicos para aumentar a satisfação e melhorar a usabilidade estão relacionados à facilidade de compreensão e à simplicidade no uso, o que pode ser obtido por meio de melhorias relacionadas à aplicação da tecnologia, ao conhecimento dos processos cognitivos dos usuários e à aplicação de conceitos semióticos de comunicação. O estudo pode servir de base para o desenvolvimento e análise de guias de uso de outros apps com características similares, em diversos sistemas operacionais.

  1. DESCRIPCIÓN DE UN DISPOSITIVO DESTINADO AL ANÁLISIS DE LA MARCHA EN DOS DIMENSIONES, CineMED

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    Christian Andrés Díaz

    Full Text Available Este artículo presenta un dispositivo para el análisis cinemático de la marcha humana. El dispositivo propuesto se basa en el uso de técnicas de videogrametría y procesamiento de imágenes para registrar el movimiento humano. Con este fin, se utilizó una cámara de video digital, ubicada a 4 metros del paciente, capturando su marcha en el plano sagital. También se desarrolló un modelo cinemático de los miembros inferiores que, a partir del desplazamiento de cierto número de puntos anatómicos, determina los ángulos articulares de la cadera, rodilla y tobillo, además de la inclinación de la pelvis durante un ciclo completo de la marcha. La identificación de dichos puntos fue facilitada mediante el uso de marcadores reflectivos, ubicados en siete posiciones anatómicas diferentes. Después, se diseñó y desarrolló un programa para el registro y procesamiento de los datos obtenidos, por medio de la cámara en el lenguaje de programación C# .NET. La aplicación desarrollada captura y preprocesa el video, detecta cada uno de los marcadores en la imagen, aplica el modelo cinemático y visualiza a modo de gráfica el valor de los ángulos articulares de los miembros inferiores, a lo largo del ciclo de la marcha. Por fin, se diseñó un protocolo y se realizó una prueba experimental con un sujeto, para comparar las curvas entregadas por el software y las curvas teóricas encontradas en la literatura. A pesar de las limitaciones del sistema referentes al análisis bidimensional de la marcha, se lograron obtener curvas articulares muy similares a las teóricas, obtenidas con métodos comerciales para el análisis del movimiento tridimensional.

  2. Integración de dispositivos físicos en un laboratorio remoto de control mediante diferentes plataformas: Labview, Matlab y C/C++

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    R. Costa-Castelló

    2010-01-01

    Full Text Available Resumen: Los laboratorios remotos de control posibilitan la realización de prácticas con equipos físicos reales que se encuentran ubicados en entornos remotos siendo accesibles por parte de los alumnos en cualquier instante de tiempo y desde cualquier lugar con conexión a Internet. En este artículo se presenta un conjunto de dispositivos físicos incorporados dentro de una esquema global de laboratorios remotos (AutomatL@bs que posibilitan la realización de prácticas a distancia con estos dispositivos. El rasgo principal común a estos dispositivos consiste en que posibilitan la actuación con sistemas físicos remotos para la realización de prácticas de control clásico con los mismos. Se prestará una especial atención a las diferentes posibilidades de comunicación entre la herramienta visual que dispone el usuario para su interconexión basada en Easy Java Simulations, y la conexión directa con los dispositivos físicos ubicados en los laboratorios remotos. Estos sistemas se han empleado para la realización de prácticas dentro del sistema AutomatL@bs desde el curso 1997/98. Palabras clave: Educación en Control, Laboratorio remoto, Laboratorio virtual, Control remoto, Control PID, Técnicas de Laboratorio

  3. Innovación tecnológica: dispositivo para el rodillado, en tornos horizontales, de los muñones de ejes.

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    Asdrúbal García Domínguez

    2012-06-01

    Full Text Available Consiste en el diseño de un dispositivo para el rodillado, adaptado a torno horizontal, para la deformación plástica superficial, mediante la aplicación de rodillos, para el reacondicionamiento de ejes dañados en los muñones producto del rozamiento durante su trabajo. Hay ejes que trabajan en condiciones de gran contaminación por suciedades y a bajas velocidades soportando altas solicitaciones, en contacto con cojinetes de deslizamiento lubricados por salpicadura. Después de dos o tres años de trabajo tienen que retirarse de explotación debido al alto deterioro de los muñones, a pesar de que interiormente no presentan ningún síntoma de fatiga. Después de realizarle el tratamiento superficial, con el dispositivo de la invención, tardan el doble de tiempo para que aparezcan los síntomas de deterioro. Se diseñó, fabricó y puso en explotación un dispositivo adaptado al torno horizontal. Se aplicó para la recuperación de los ejes de los carros jaula ferroviarios para el transporte de la caña de azúcar. El dispositivo garantiza la calidad de acabado superficial y resistencia al desgaste, sin afectar las exigencias de la seguridad ferroviaria.Palabras claves: rodillado de superficies cilíndricas; deformación plástica superficial.

  4. Percutaneous and skeletal biocarbon implants

    Science.gov (United States)

    Mooney, V.

    1977-01-01

    Review of carbon implants developed by NASA discussed four different types of implants and subsequent improvements. Improvements could be of specific interest to rehabilitation centers and similar organizations.

  5. Degradable Implantate: Entwicklungsbeispiele

    Science.gov (United States)

    Ruffieux, Kurt; Wintermantel, Erich

    Resorbierbare Implantate werden seit mehreren Jahrzehnten in der Implantologie eingesetzt. Bekannt wurden diese Biomaterialien mit dem Aufkommen von sich selbst auflösenden Nahtfäden auf der Basis von synthetisch hergestellten Polylactiden und Polyglycoliden in den 70er Jahren. In einem nächsten Schritt wurden Implantate wie Platten und Schrauben zur Gewebefixation aus den gleichen Biomaterialien hergestellt.

  6. Risks of Breast Implants

    Science.gov (United States)

    ... have a risk of developing a type of cancer called breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) in the breast tissue surrounding the implant. BIA-ALCL is not breast cancer. Women diagnosed with BIA-ALCL may need to ...

  7. Ion implantation of metals

    International Nuclear Information System (INIS)

    Dearnaley, G.

    1976-01-01

    In this part of the paper descriptions are given of the effects of ion implantation on (a) friction and wear in metals; and (b) corrosion of metals. In the study of corrosion, ion implantation can be used either to introduce a constituent that is known to convey corrosion resistance, or more generally to examine the parameters which control corrosion. (U.K.)

  8. Ion implantation into diamond

    International Nuclear Information System (INIS)

    Sato, Susumu

    1994-01-01

    The graphitization and the change to amorphous state of diamond surface layer by ion implantation and its characteristics are reported. In the diamond surface, into which more than 10 16 ions/cm 2 was implanted, the diamond crystals are broken, and the structure changes to other carbon structure such as amorphous state or graphite. Accompanying this change of structure, the electric conductivity of the implanted layer shows two discontinuous values due to high resistance and low resistance. This control of structure can be done by the temperature of the base during the ion implantation into diamond. Also it is referred to that by the base temperature during implantation, the mutual change of the structure between amorphous state and graphite can be controlled. The change of the electric resistance and the optical characteristics by the ion implantation into diamond surface, the structural analysis by Raman spectroscopy, and the control of the structure of the implanted layer by the base temperature during implantation are reported. (K.I.)

  9. Number of implants for mandibular implant overdentures: a systematic review

    Science.gov (United States)

    Lee, Jeong-Yol; Kim, Ha-Young; Bryant, S. Ross

    2012-01-01

    PURPOSE The aim of this systematic review is to address treatment outcomes of Mandibular implant overdentures relative to implant survival rate, maintenance and complications, and patient satisfaction. MATERIALS AND METHODS A systematic literature search was conducted by a PubMed search strategy and hand-searching of relevant journals from included studies. Randomized Clinical Trials (RCT) and comparative clinical trial studies on mandibular implant overdentures until August, 2010 were selected. Eleven studies from 1098 studies were finally selected and data were analyzed relative to number of implants. RESULTS Six studies presented the data of the implant survival rate which ranged from 95% to 100% for 2 and 4 implant group and from 81.8% to 96.1% for 1 and 2 implant group. One study, which statistically compared implant survival rate showed no significant differences relative to the number of implants. The most common type of prosthetic maintenance and complications were replacement or reattaching of loose clips for 2 and 4 implant group, and denture repair due to the fracture around an implant for 1 and 2 implant groups. Most studies showed no significant differences in the rate of prosthetic maintenance and complication, and patient satisfaction regardless the number of implants. CONCLUSION The implant survival rate of mandibular overdentures is high regardless of the number of implants. Denture maintenance is likely not inflenced substantially by the number of implants and patient satisfaction is typically high again regardless os the number of implants. PMID:23236572

  10. Ion implantation into iron

    International Nuclear Information System (INIS)

    Iwaki, Masaya

    1978-01-01

    The distribution of implanted ions in iron, the friction characteristics and the corrosion of iron were studied. The distribution of Ni or Cr ions implanted into mild steel was measured. The accelerated voltage was 150 keV, and the beam current density was about 2 microampere/cm 2 . The measurement was made with an ion microanalyzer. The measured distribution was compared with that of LSS theory. Deep invasion of Ni was seen in the measured distribution. The distribution of Cr ions was different from the distribution calculated by the LSS theory. The relative friction coefficient of mild steel varied according to the dose of implanted Cu or N ions, and to the accelerating voltage. Formation of compound metals on the surfaces of metals by ion-implantation was investigated for the purpose to prevent the corrosion of metals. The resistance of mild steel in which Ni ions were implanted was larger than that of mild steel without any treatment. (Kato, T.)

  11. La depresión: encrucijada entre las nuevas modalidades del ser y el dispositivo farmacéutico

    Directory of Open Access Journals (Sweden)

    Diego E. Londoño

    2013-12-01

    Full Text Available Siguiendo la tesis del sociólogo Alain Ehrenberg, la depresión se instaló en las sociedades occidentales como una consecuencia de las nuevas modalidades del individuo. La emancipación y la soberanía individual comenzadas en el siglo de las luces trajeron consigo nuevos malestares de la mente. La neurastenia resume la primera “epidemia” mundial que muestra las consecuencias de estas mutaciones antropológicas. La neurosis y el psicoanálisis demuestran que la depresión y otras formas de sufrimiento de las personas ordinarias son el resultado de un precio a pagar por entrar en la civilización. Para Ehrenberg, la epidemia contemporánea de depresión es el rostro de un eclipse de la culpabilidad y el conflicto interior, favoreciendo una apertura de infinitas posibilidades y la consagración personal como nuevos ideales constitutivos de la personalidad y la identidad, siendo la depresión una disfunción o insuficiencia a convertirse en uno mismo. Sin embargo, las tesis de Ehrenberg no toman en cuenta el esfuerzo realizado por la industria farmacéutica y el dispositivo comercial y de mercadeo creado para modificar las costumbres y el saber médico, facilitando así la explosión diagnóstica y autodiagnóstica de este trastorno controversial.

  12. Learning in archaeological sites with mobile devices = Aprendizaje con dispositivos móviles en yacimientos arqueológicos

    Directory of Open Access Journals (Sweden)

    IBÁÑEZ-ETXEBERRIA, A., VICENT, N., ASENSIO, M., CUENCA, J.M., FONTAL, O.

    2014-01-01

    Full Text Available La relevancia social del mobile learning es cada vez más evidente. Estos mecanismos, a través de TICs y dispositivos móviles, se aplican ya en programas educativos en yacimientos arqueológicos y museos, pero la pregunta es si estos programas son efectivos para el aprendizaje. Para investigar esta cuestión, hemos evaluado la implementación de un programa educativo con contenidos histórico- patrimoniales ofertado para estudiantes de secundaria. Noventa estudiantes participaron en este estudio respondiendo un cuestionario que abordaba cuestiones relacionadas con la asimilación de contenidos conceptuales, la atención y la eficacia del programa, así como aspectos relacionados con la satisfacción, utilidad percibida y dificultad de uso de la tecnología móvil. Los resultados son satisfactorios respecto a la asimilación de contenidos, y se aprecian mejores resultados con la combinación de metodologías receptivas y el uso de tecnología móvil. La satisfacción y la percepción de la utilidad confirman los buenos resultados de anteriores trabajos.

  13. Perspectivas e desafios dos dispositivos móveis para as bibliotecas universitárias brasileiras

    Directory of Open Access Journals (Sweden)

    Angel Freddy

    2018-01-01

    Full Text Available Pesquisa quantitativa documental realizada nas bibliotecas universitárias federais brasileiras para veri car o nível de adequação ao fenômeno móvel, através de um conjunto de variáveis que mostram quais ações as bibliotecas estão desenvolvendo para atender os usuários de dispositivos móveis. Foi observado o uso de aplicativos, a adaptação dos catálogos, uso de redes sociais, entre outras variáveis. Os resultados foram comparados com as 100 (cem bibliotecas acadêmicas melhor avaliadas em 2014 nos EUA segundo o ranking nacional de universidades. Para este trabalho foi realizada pesquisa na base Scopus para identi car pesquisas relacionadas ao uso de plataformas móveis nos serviços de bibliotecas. Conclui que as bibliotecas brasileiras estão atuando de várias formas para atender a nova demanda móvel, mas é necessário atenção e ação na conversão dos serviços para criar novo modelo de relacionamento com os usuários baseado na mobilidade e ubiquidade.

  14. Aproximación al modelado del componente conceptual básico del Dispositivo Hipermedial Dinámico

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    Rodríguez, Guillermo L.

    2011-01-01

    Full Text Available El presente trabajo interdisciplinario, propone una primera aproximación conceptual y de uso al modelado descriptivo y de simulación para el análisis del Dispositivo Hipermedial Dinámico con la finalidad de avanzar hacia la generación de configuraciones más efectivas que posibiliten desarrollos e implementaciones tanto de tecnologías sociales como digitales para la construcción de variadas alternativas de integración responsable de las TIC. Se plantea la utilización del formalismo DEVS (Discrete EVents dynamic Systems que propone una teoría de modelado de sistemas a tiempo continuo usando modelado de eventos discretos. En ese sentido, se presenta el modelado y simulación del denominado "Paquete Hipermedial", como componente conceptual básico del DHD. Lo expuesto aporta un posible camino hacia el análisis evaluativo sobre cómo se desarrollan o se podrían implementar procesos de participación responsable a través de redes sociotécnicas que tengan por objeto investigar, educar y producir en actual contexto físico-virtual.

  15. Influence of Palatal Coverage and Implant Distribution on Implant Strain in Maxillary Implant Overdentures.

    Science.gov (United States)

    Takahashi, Toshihito; Gonda, Tomoya; Mizuno, Yoko; Fujinami, Yozo; Maeda, Yoshinobu

    2016-01-01

    Maxillary implant overdentures are often used in clinical practice. However, there is no agreement or established guidelines regarding prosthetic design or optimal implant placement configuration. The purpose of this study was to examine the influence of palatal coverage and implant number and distribution in relation to impact strain under maxillary implant overdentures. A maxillary edentulous model with implants and experimental overdentures with and without palatal coverage was fabricated. Four strain gauges were attached to each implant, and they were positioned in the anterior, premolar, and molar areas. A vertical occlusal load of 98 N was applied through a mandibular complete denture, and the implant strains were compared using one-way analysis of variance (P = .05). The palatolabial strain was much higher on anterior implants than on other implants in both denture types. Although there was no significant difference between the strain under dentures with and without palatal coverage, palateless dentures tended to result in higher implant strain than dentures with palatal coverage. Dentures supported by only two implants registered higher strain than those supported by four or six implants. Implants under palateless dentures registered higher strain than those under dentures with palatal coverage. Anterior implants exhibited higher palatolabial strain than other implants regardless of palatal coverage and implant configuration; it is therefore recommended that maxillary implant overdentures should be supported by six implants with support extending to the distal end of the arch.

  16. Polymer-coated albumin microspheres as carriers for intravascular tumour targeting of cisplatin.

    Science.gov (United States)

    Verrijk, R; Smolders, I J; McVie, J G; Begg, A C

    1991-01-01

    We used a poly-lactide-co-glycolide polymer (PLAGA 50:50) to formulate cisplatin (cDDP) into microspheres designed for intravascular administration. Two systems were developed. PLAGA-coated albumin microspheres and microspheres consisting of PLAGA only. PLAGA-coated microspheres displayed a mean diameter of 31.8 +/- 0.9 microns and a payload of 7.5% cDDP (w/w). Solid PLAGA microspheres exhibited a mean diameter of 19.4 +/- 0.6 microns and a payload of 20% cDDP. Release characteristics and in vitro effects on L1210 leukemia and B16 melanoma cell lines were investigated. Both types of microsphere overcame the initial rapid release of cDDP (burst effect), and PLAGA-coated albumin microspheres also showed a lag phase of approximately 30 min before cDDP release began. PLAGA-coated albumin microspheres released most of their payload through diffusion, and the coating eventually cracked after 7 days' incubation in saline supplemented with 0.1% Tween at 37 degrees C, enabling the release of any cDDP remaining. Effects of platinum, pre-released from PLAGA-coated albumin microspheres on the in vitro growth of L1210 cells were comparable with those of standard formulations (dissolved) of cDDP. Material released from non-drug-loaded PLAGA microspheres had no effect on L1210 cell growth, suggesting the absence of cytotoxic compounds in the matrix. The colony-forming ability of B16 cells was also equally inhibited by standard cDDP and pre-released drug. These studies show that formulation of cDDP in PLAGA-based microspheres prevents the rapid burst effect of cDDP seen in previous preparations and offers an improved system of administration for hepatic artery infusion or adjuvant therapy, enabling better clinical handling and the promise of a higher ratio of tumour tissue to normal tissue.

  17. Abnormal pulmonary artery stiffness in pulmonary arterial hypertension: in vivo study with intravascular ultrasound.

    Directory of Open Access Journals (Sweden)

    Edmund M T Lau

    Full Text Available BACKGROUND: There is increasing recognition that pulmonary artery stiffness is an important determinant of right ventricular (RV afterload in pulmonary arterial hypertension (PAH. We used intravascular ultrasound (IVUS to evaluate the mechanical properties of the elastic pulmonary arteries (PA in subjects with PAH, and assessed the effects of PAH-specific therapy on indices of arterial stiffness. METHOD: Using IVUS and simultaneous right heart catheterisation, 20 pulmonary segments in 8 PAH subjects and 12 pulmonary segments in 8 controls were studied to determine their compliance, distensibility, elastic modulus and stiffness index β. PAH subjects underwent repeat IVUS examinations after 6-months of bosentan therapy. RESULTS: AT BASELINE, PAH SUBJECTS DEMONSTRATED GREATER STIFFNESS IN ALL MEASURED INDICES COMPARED TO CONTROLS: compliance (1.50±0.11×10(-2 mm(2/mmHg vs 4.49±0.43×10(-2 mm(2/mmHg, p<0.0001, distensibility (0.32±0.03%/mmHg vs 1.18±0.13%/mmHg, p<0.0001, elastic modulus (720±64 mmHg vs 198±19 mmHg, p<0.0001, and stiffness index β (15.0±1.4 vs 11.0±0.7, p = 0.046. Strong inverse exponential associations existed between mean pulmonary artery pressure and compliance (r(2 = 0.82, p<0.0001, and also between mean PAP and distensibility (r(2 = 0.79, p = 0.002. Bosentan therapy, for 6-months, was not associated with any significant changes in all indices of PA stiffness. CONCLUSION: Increased stiffness occurs in the proximal elastic PA in patients with PAH and contributes to the pathogenesis RV failure. Bosentan therapy may not be effective at improving PA stiffness.

  18. Voxel-based plaque classification in coronary intravascular optical coherence tomography images using decision trees

    Science.gov (United States)

    Kolluru, Chaitanya; Prabhu, David; Gharaibeh, Yazan; Wu, Hao; Wilson, David L.

    2018-02-01

    Intravascular Optical Coherence Tomography (IVOCT) is a high contrast, 3D microscopic imaging technique that can be used to assess atherosclerosis and guide stent interventions. Despite its advantages, IVOCT image interpretation is challenging and time consuming with over 500 image frames generated in a single pullback volume. We have developed a method to classify voxel plaque types in IVOCT images using machine learning. To train and test the classifier, we have used our unique database of labeled cadaver vessel IVOCT images accurately registered to gold standard cryoimages. This database currently contains 300 images and is growing. Each voxel is labeled as fibrotic, lipid-rich, calcified or other. Optical attenuation, intensity and texture features were extracted for each voxel and were used to build a decision tree classifier for multi-class classification. Five-fold cross-validation across images gave accuracies of 96 % +/- 0.01 %, 90 +/- 0.02% and 90 % +/- 0.01 % for fibrotic, lipid-rich and calcified classes respectively. To rectify performance degradation seen in left out vessel specimens as opposed to left out images, we are adding data and reducing features to limit overfitting. Following spatial noise cleaning, important vascular regions were unambiguous in display. We developed displays that enable physicians to make rapid determination of calcified and lipid regions. This will inform treatment decisions such as the need for devices (e.g., atherectomy or scoring balloon in the case of calcifications) or extended stent lengths to ensure coverage of lipid regions prone to injury at the edge of a stent.

  19. Exogenous normal lymph alleviates microcirculation disturbances and abnormal hemorheological properties in rats with disseminated intravascular coagulation

    International Nuclear Information System (INIS)

    Niu, Chun-Yu; Zhao, Zi-Gang; Zhang, Yu-Ping; Hou, Ya-Li; Li, Jun-Jie; Jiang, Hua; Zhang, Jing

    2013-01-01

    Disturbances of the microcirculation and abnormal hemorheological properties are important factors that play an important role in disseminated intravascular coagulation (DIC) and result in organ dysfunction or failure. In the present study, we established an animal model of DIC using intravenous Dextran 500 in rats, and used exogenous normal lymph corresponding to 1/15 of whole blood volume for injection through the left jugular vein. We found that normal lymph could improve the blood pressure and survival time of rats with DIC. The results regarding the mesenteric microcirculation showed that the abnormality of the diameter of mesenteric microvessels and micro-blood flow speed in the DIC+lymph group was significantly less than in the DIC+saline group. Whole blood viscosity, relative viscosity, plasma viscosity, hematocrit (Hct), erythrocyte sedimentation rate (ESR), and electrophoresis time of erythrocytes were significantly increased in the DIC+saline group compared to the control group. The electrophoretic length and migration of erythrocytes from the DIC+saline and DIC+lymph groups were significantly slower than the control group. Blood relative viscosity, Hct, ESR, and electrophoretic time of erythrocytes were significantly increased in the DIC+lymph group compared to the control group. Whole blood viscosity, relative viscosity and reduced viscosity were significantly lower in the DIC+lymph group than in the DIC+saline group, and erythrocyte deformability index was also significantly higher than in the DIC+saline and control groups. These results suggest that exogenous normal lymph could markedly improve the acute microcirculation disturbance and the abnormal hemorheological properties in rats with DIC induced by Dextran 500

  20. Dextran or Saline Can Replace Contrast for Intravascular Optical Coherence Tomography in Lower Extremity Arteries.

    Science.gov (United States)

    Kendrick, Daniel E; Allemang, Matthew T; Gosling, Andre F; Nagavalli, Anil; Kim, Ann H; Nishino, Setsu; Parikh, Sahil A; Bezerra, Hiram G; Kashyap, Vikram S

    2016-10-01

    To examine the hypothesis that alternative flush media could be used for lower extremity optical coherence tomography (OCT) imaging in long lesions that would normally require excessive use of contrast. The OPTical Imaging Measurement of Intravascular Solution Efficacy (OPTIMISE) trial was a single-center, prospective study (ClinicalTrials.gov identifier NCT01743872) that enrolled 23 patients (mean age 68±11 years; 14 men) undergoing endovascular intervention involving the superficial femoral artery. Four flush media (heparinized saline, dextran, carbon dioxide, and contrast) were used in succession in random order for each image pullback. Quality was defined as ≥270° visualization of vessel wall layers from each axial image. Mean proportions (± standard deviation) of image quality for each flush medium were assessed using 1-way analysis of variance and are reported with the 95% confidence intervals (CI). Four OCT catheters failed, leaving 19 patients who completed the OCT imaging protocol; from this cohort, 51 highest quality runs were selected for analysis. Average vessel diameter was 3.99±1.01 mm. OCT imaging allowed 10- to 15-μm resolution of the lumen border, with diminishing quality as vessel diameter increased. Plaque characterization revealed fibrotic lesions. Mean proportions of image quality were dextran 87.2%±12% (95% CI 0.81 to 0.94), heparinized saline 74.3%±24.8% (95% CI 0.66 to 0.93), contrast 70.1%±30.5% (95% CI 0.52 to 0.88), and carbon dioxide 10.0%±10.4% (95% CI 0.00 to 0.26). Dextran, saline, and contrast provided better quality than carbon dioxide (pDextran or saline flush media can allow lesion characterization, avoiding iodinated contrast. Carbon dioxide is inadequate for peripheral OCT imaging. Axial imaging may aid in enhancing durability of peripheral endovascular interventions. © The Author(s) 2016.

  1. Exogenous normal lymph alleviates microcirculation disturbances and abnormal hemorheological properties in rats with disseminated intravascular coagulation

    Energy Technology Data Exchange (ETDEWEB)

    Niu, Chun-Yu; Zhao, Zi-Gang; Zhang, Yu-Ping [Institute of Microcirculation, Hebei North University, Zhangjiakou (China); Hou, Ya-Li [Department of Clinical Laboratory, First Affiliated Hospital, Hebei North University, Zhangjiakou (China); Li, Jun-Jie; Jiang, Hua; Zhang, Jing [Institute of Microcirculation, Hebei North University, Zhangjiakou (China)

    2013-02-01

    Disturbances of the microcirculation and abnormal hemorheological properties are important factors that play an important role in disseminated intravascular coagulation (DIC) and result in organ dysfunction or failure. In the present study, we established an animal model of DIC using intravenous Dextran 500 in rats, and used exogenous normal lymph corresponding to 1/15 of whole blood volume for injection through the left jugular vein. We found that normal lymph could improve the blood pressure and survival time of rats with DIC. The results regarding the mesenteric microcirculation showed that the abnormality of the diameter of mesenteric microvessels and micro-blood flow speed in the DIC+lymph group was significantly less than in the DIC+saline group. Whole blood viscosity, relative viscosity, plasma viscosity, hematocrit (Hct), erythrocyte sedimentation rate (ESR), and electrophoresis time of erythrocytes were significantly increased in the DIC+saline group compared to the control group. The electrophoretic length and migration of erythrocytes from the DIC+saline and DIC+lymph groups were significantly slower than the control group. Blood relative viscosity, Hct, ESR, and electrophoretic time of erythrocytes were significantly increased in the DIC+lymph group compared to the control group. Whole blood viscosity, relative viscosity and reduced viscosity were significantly lower in the DIC+lymph group than in the DIC+saline group, and erythrocyte deformability index was also significantly higher than in the DIC+saline and control groups. These results suggest that exogenous normal lymph could markedly improve the acute microcirculation disturbance and the abnormal hemorheological properties in rats with DIC induced by Dextran 500.

  2. Protocatechuic aldehyde inhibits migration and proliferation of vascular smooth muscle cells and intravascular thrombosis

    Energy Technology Data Exchange (ETDEWEB)

    Moon, Chang Yoon [The Hotchkiss School, Lakeville, CT (United States); Endocrinology, Brain Korea 21 Project for Medical Science, Institute of Endocrine Research, and Severance Integrative Research Institute for Cerebral and Cardiovascular Disease, Yonsei University College of Medicine, Seoul (Korea, Republic of); Ku, Cheol Ryong [Endocrinology, Brain Korea 21 Project for Medical Science, Institute of Endocrine Research, and Severance Integrative Research Institute for Cerebral and Cardiovascular Disease, Yonsei University College of Medicine, Seoul (Korea, Republic of); Cho, Yoon Hee, E-mail: wooriminji@gmail.com [Endocrinology, Brain Korea 21 Project for Medical Science, Institute of Endocrine Research, and Severance Integrative Research Institute for Cerebral and Cardiovascular Disease, Yonsei University College of Medicine, Seoul (Korea, Republic of); Lee, Eun Jig, E-mail: ejlee423@yuhs.ac [Endocrinology, Brain Korea 21 Project for Medical Science, Institute of Endocrine Research, and Severance Integrative Research Institute for Cerebral and Cardiovascular Disease, Yonsei University College of Medicine, Seoul (Korea, Republic of); Endocrinology, Northwestern University Feinberg School of Medicine, Chicago, IL (United States)

    2012-06-22

    Highlights: Black-Right-Pointing-Pointer Protocatechuic aldehyde (PCA) inhibits ROS production in VSMCs. Black-Right-Pointing-Pointer PCA inhibits proliferation and migration in PDGF-induced VSMCs. Black-Right-Pointing-Pointer PCA has anti-platelet effects in ex vivo rat whole blood. Black-Right-Pointing-Pointer We report the potential therapeutic role of PCA in atherosclerosis. -- Abstract: The migration and proliferation of vascular smooth muscle cells (VSMCs) and formation of intravascular thrombosis play crucial roles in the development of atherosclerotic lesions. This study examined the effects of protocatechuic aldehyde (PCA), a compound isolated from the aqueous extract of the root of Salvia miltiorrhiza, an herb used in traditional Chinese medicine to treat a variety of vascular diseases, on the migration and proliferation of VSMCs and platelets due to platelet-derived growth factor (PDGF). DNA 5-bromo-2 Prime -deoxy-uridine (BrdU) incorporation and wound-healing assays indicated that PCA significantly attenuated PDGF-induced proliferation and migration of VSMCs at a pharmacologically relevant concentration (100 {mu}M). On a molecular level, we observed down-regulation of the phosphatidylinositol 3-kinase (PI3K)/Akt and the mitogen-activated protein kinase (MAPK) pathways, both of which regulate key enzymes associated with migration and proliferation. We also found that PCA induced S-phase arrest of the VSMC cell cycle and suppressed cyclin D2 expression. In addition, PCA inhibited PDGF-BB-stimulated reactive oxygen species production in VSMCs, indicating that PCA's antioxidant properties may contribute to its suppression of PDGF-induced migration and proliferation in VSMCs. Finally, PCA exhibited an anti-thrombotic effect related to its inhibition of platelet aggregation, confirmed with an aggregometer. Together, these findings suggest a potential therapeutic role of PCA in the treatment of atherosclerosis and angioplasty-induced vascular restenosis.

  3. Assessing intravascular volume by difference in pulse pressure in pigs submitted to graded hemorrhage.

    Science.gov (United States)

    Pestel, Gunther J; Hiltebrand, Luzius B; Fukui, Kimiko; Cohen, Delphine; Hager, Helmut; Kurz, Andrea M

    2006-10-01

    We assessed changes in intravascular volume monitored by difference in pulse pressure (dPP%) after stepwise hemorrhage in an experimental pig model. Six pigs (23-25 kg) were anesthetized (isoflurane 1.5 vol%) and mechanically ventilated to keep end-tidal CO2 (etCO2) at 35 mmHg. A PA-catheter and an arterial catheter were placed via femoral access. During and after surgery, animals received lactated Ringer's solution as long as they were considered volume responders (dPP>13%). Then animals were allowed to stabilize from the induction of anesthesia and insertion of catheters for 30 min. After stabilization, baseline measurements were taken. Five percent of blood volume was withdrawn, followed by another 5%, and then in 10%-increments until death from exsanguination occurred. After withdrawal of 5% of blood volume, all pigs were considered volume responders (dPP>13%); dPP rose significantly from 6.1+/-3.3% to 19.4+/-4.2%. The regression analysis of stepwise hemorrhage revealed a linear relation between blood loss (hemorrhage in %) and dPP (y=0.99*x+14; R2=0.7764; P<.0001). In addition, dPP was the only parameter that changed significantly between baseline and a blood loss of 5% (P<0.01), whereas cardiac output, stroke volume, heart rate, MAP, central venous pressure, pulmonary artery occlusion pressure, and systemic vascular resistance, respectively, remained unchanged. We conclude that in an experimental hypovolemic pig model, dPP correlates well with blood loss.

  4. An experimental study on the influence of the intravascular gianturco type stents on the vascular structures

    Energy Technology Data Exchange (ETDEWEB)

    Choe, Yeon Hyeon [Sejong General Hospital, Bucheon (Korea, Republic of); Park, Jae Hyung; Han, Joon Koo; Han, Man Chung; Kim, Chu Wan [College of Medicine, Seoul National University, Seoul (Korea, Republic of)

    1991-07-15

    Twenty-seven Gianturco-type self-expandable stainless steel intravascular stents were placed into the infrarenal abdominal aortas (n=17) and inferior venae cavae (n=10) in 14 mongrel dogs. In 8 aortas, stents were delivered after balloon catheter-induced denudation of the intima, and in 4 out of the 8 aortas, the stents were also placed into the normal sites to compare the neointimal thickness of the normal and denuded sites. Angiography, light microscopic, and scanning electron microscopic examinations were performed after 1 week (n=1), 2 weeks (n=6), 3 weeks (n=5), and 6 weeks (n=2). The patency rate and thrombosis rate were 100% and 35% in the aortas and 100% and 60% in the inferior venae cavae. The aortic stent wires were covered with thin fibrinous membrane after 1 week. Nearly complete transparent neointimal covering was found in the aortas and caval veins after 2 weeks. There was no significant difference in intimal thickness between the denuded and normal aortas after 2 weeks ({rho} =0.51) and 3 weeks ({rho} =0.56). In 4 dogs with caval vein stents, there was evidence of hemorrhage infarction in the lungs. The thrombosis rate of 12 stents with a stent-artery ratio (SAR) of 1.5 or higher was 41%, while there was no thrombus on the 4 stents with SAR 1.2 or lower, except for 1 specimen after 1 week. It is suggested that stents with SAR 1.2 or lower are more suitable. The high thrombosis rate of the inferior venae cavae may be related with slow blood flow.

  5. Endothelial progenitor cell mobilization and increased intravascular nitric oxide in patients undergoing cardiac rehabilitation.

    Science.gov (United States)

    Paul, Jonathan D; Powell, Tiffany M; Thompson, Michael; Benjamin, Moshe; Rodrigo, Maria; Carlow, Andrea; Annavajjhala, Vidhya; Shiva, Sruti; Dejam, Andre; Gladwin, Mark T; McCoy, J Philip; Zalos, Gloria; Press, Beverly; Murphy, Mandy; Hill, Jonathan M; Csako, Gyorgy; Waclawiw, Myron A; Cannon, Richard O

    2007-01-01

    We investigated whether cardiac rehabilitation participation increases circulating endothelial progenitor cells (EPCs) and benefits vasculature in patients already on stable therapy previously shown to augment EPCs and improve endothelial function. Forty-six of 50 patients with coronary artery disease completed a 36-session cardiac rehabilitation program: 45 were treated with HMG-CoA reductase inhibitor (statin) therapy > or = 1 month (average baseline low-density lipoprotein cholesterol = 81 mg/dL). Mononuclear cells isolated from blood were quantified for EPCs by flow cytometry (CD133/VEGFR-2 cells) and assayed in culture for EPC colony-forming units (CFUs). In 23 patients, EPCs were stained for annexin-V as a marker of apoptosis, and nitrite was measured in blood as an indicator of intravascular nitric oxide. Endothelial progenitor cells increased from 35 +/- 5 to 63 +/- 10 cells/mL, and EPC-CFUs increased from 0.9 +/- 0.2 to 3.1 +/- 0.6 per well (both P < .01), but 11 patients had no increase in either measure. Those patients whose EPCs increased from baseline showed significant increases in nitrite and reduction in annexin-V staining (both P < .01) versus no change in patients without increase in EPCs. Over the course of the program, EPCs increased prior to increase in nitrite in the blood. Cardiac rehabilitation in patients receiving stable statin therapy and with low-density lipoprotein cholesterol at goal increases EPC number, EPC survival, and endothelial differentiation potential, associated with increased nitric oxide in the blood. Although this response was observed in most patients, a significant minority showed neither EPC mobilization nor increased nitric oxide in the blood.

  6. In-111-oxine labeled platelet scintigraphy for detection of intracardiac and intravascular thrombi

    Energy Technology Data Exchange (ETDEWEB)

    Hanano, Masaharu; Kimura, Michio; Ojima, Kenji [Niigata Univ. (Japan). School of Medicine

    1984-06-01

    /sup 111/In-labeled platelet scintigraphy was carried out in 20 patients suspected of thrombosis, to evaluate its efficacy for the detection of intracardiac and intravascular thrombi. Hemostatic studies including PT, aPTT, fibrinogen, FDP, platelet retention by Hellem II method, platelet aggregation induced by ADP (1 ..mu..M, 10 ..mu..M), collagen (2 ..mu..g/ml) and arachidonate (2 mM), and platelet survival were examined simultaneously. Two of these patients were also studied by fibrinogen scintigraphy labeled with sup(99m)Tc. The platelets obtained from the patients were labeled with /sup 111/In-oxine according to a method originated by Yui et al. In the platelet scintigram, positive findings were demonstrated in 9 cases : 2 left ventricular, 3 left atrial, and 4 vascular thrombi. These were in a good accordance to the findings obtained by at least one from angiography, echography and surgery. Platelet aggregation induced by 1 ..mu..M ADP was elevated in 4 of the 7 patients with positive findings and 3 of the 7 patients with negative findings. Shortened platelet survivals were observed in two of the 10 patients; dissecting aortic aneurysm and infective prosthetic valve endocarditis with hepatosplenomegaly. There was no significant difference in the platelet function and the platelet survival between the patients with positive and negative findings. It was difficult to detect thrombi by the fibrinogen scintigraphy labeled with sup(99m)Tc in the two patients studied. In conclusion, /sup 111/In-labeled platelet scintigraphy seems to be very useful to detect thrombi.

  7. Multidimensional segmentation of coronary intravascular ultrasound images using knowledge-based methods

    Science.gov (United States)

    Olszewski, Mark E.; Wahle, Andreas; Vigmostad, Sarah C.; Sonka, Milan

    2005-04-01

    In vivo studies of the relationships that exist among vascular geometry, plaque morphology, and hemodynamics have recently been made possible through the development of a system that accurately reconstructs coronary arteries imaged by x-ray angiography and intravascular ultrasound (IVUS) in three dimensions. Currently, the bottleneck of the system is the segmentation of the IVUS images. It is well known that IVUS images contain numerous artifacts from various sources. Previous attempts to create automated IVUS segmentation systems have suffered from either a cost function that does not include enough information, or from a non-optimal segmentation algorithm. The approach presented in this paper seeks to strengthen both of those weaknesses -- first by building a robust, knowledge-based cost function, and then by using a fully optimal, three-dimensional segmentation algorithm. The cost function contains three categories of information: a compendium of learned border patterns, information theoretic and statistical properties related to the imaging physics, and local image features. By combining these criteria in an optimal way, weaknesses associated with cost functions that only try to optimize a single criterion are minimized. This cost function is then used as the input to a fully optimal, three-dimensional, graph search-based segmentation algorithm. The resulting system has been validated against a set of manually traced IVUS image sets. Results did not show any bias, with a mean unsigned luminal border positioning error of 0.180 +/- 0.027 mm and an adventitial border positioning error of 0.200 +/- 0.069 mm.

  8. Improved automated lumen contour detection by novel multifrequency processing algorithm with current intravascular ultrasound system.

    Science.gov (United States)

    Kume, Teruyoshi; Kim, Byeong-Keuk; Waseda, Katsuhisa; Sathyanarayana, Shashidhar; Li, Wenguang; Teo, Tat-Jin; Yock, Paul G; Fitzgerald, Peter J; Honda, Yasuhiro

    2013-02-01

    The aim of this study was to evaluate a new fully automated lumen border tracing system based on a novel multifrequency processing algorithm. We developed the multifrequency processing method to enhance arterial lumen detection by exploiting the differential scattering characteristics of blood and arterial tissue. The implementation of the method can be integrated into current intravascular ultrasound (IVUS) hardware. This study was performed in vivo with conventional 40-MHz IVUS catheters (Atlantis SR Pro™, Boston Scientific Corp, Natick, MA) in 43 clinical patients with coronary artery disease. A total of 522 frames were randomly selected, and lumen areas were measured after automatically tracing lumen borders with the new tracing system and a commercially available tracing system (TraceAssist™) referred to as the "conventional tracing system." The data assessed by the two automated systems were compared with the results of manual tracings by experienced IVUS analysts. New automated lumen measurements showed better agreement with manual lumen area tracings compared with those of the conventional tracing system (correlation coefficient: 0.819 vs. 0.509). When compared against manual tracings, the new algorithm also demonstrated improved systematic error (mean difference: 0.13 vs. -1.02 mm(2) ) and random variability (standard deviation of difference: 2.21 vs. 4.02 mm(2) ) compared with the conventional tracing system. This preliminary study showed that the novel fully automated tracing system based on the multifrequency processing algorithm can provide more accurate lumen border detection than current automated tracing systems and thus, offer a more reliable quantitative evaluation of lumen geometry. Copyright © 2011 Wiley Periodicals, Inc.

  9. High grade primary adrenal intravascular large B-cell lymphoma manifesting as Addison disease Linfoma intravascular de alto grado de células B grandes y origen suprarrenal que se manifiesta en forma de enfermedad de Addison

    OpenAIRE

    J. Venizelos; D. Tamiolakis; M. Lambropoulou; G. Alexiadis; G. Petrakis; N. Papadopoulos

    2007-01-01

    We report a rare case of a 68 aged male who presented with adrenal failure and was diagnosed of high grade large B-cell lymphoma primarily arising in the adrenal glands. The patient was administrated with additional chemotherapy but he passed away 7 months later due to infection in the lungs. Intravascular lymphoma should be suspected in patients with bilateral adrenal masses who present with rapidly progressive adrenal insufficiency.Publicamos el caso poco frecuente de un varón de 68 años de...

  10. Implants for orthodontic anchorage

    Science.gov (United States)

    Zheng, Xiaowen; Sun, Yannan; Zhang, Yimei; Cai, Ting; Sun, Feng; Lin, Jiuxiang

    2018-01-01

    Abstract Implantanchorage continues to receive much attention as an important orthodontic anchorage. Since the development of orthodontic implants, the scope of applications has continued to increase. Although multiple reviews detailing implants have been published, no comprehensive evaluations have been performed. Thus, the purpose of this study was to comprehensively evaluate the effects of implants based on data published in review articles. An electronic search of the Cochrane Library, Medline, Embase, Ebsco and Sicencedirect for reviews with “orthodontic” and “systematic review or meta analysis” in the title, abstract, keywords, or full text was performed. A subsequent manual search was then performed to identify reviews concerning orthodontic implants. A manual search of the orthodontic journals American Journal of Orthodontics and Dentofacial Orthopedics (AJODO), European Journal of Orthodontics (EJO), and Angle Othodontist was also performed. Such systematic reviews that evaluated the efficacy and safety of orthodontic implants were used to indicate success rates and molar movements. A total of 23 reviews were included in the analysis. The quality of each review was assessed using a measurement tool for Assessment of Multiple Systematic Reviews (AMSTAR), and the review chosen to summarize outcomes had a quality score of >6. Most reviews were less than moderate quality. Success rates of implants ranged in a broad scope, and movement of the maxillary first molar was superior with implants compared with traditional anchorage. PMID:29595673

  11. Maintenance in dental implants

    Directory of Open Access Journals (Sweden)

    Giselle Póvoa Gomes

    2008-01-01

    Full Text Available In implants, maintenance is a decisive factor for obtaining success when implant supported overdentures and dentures are used. The present stud presents, a clinical case of a patient, a 70 year-old white man, with a completely edentulous mandibular alveolar ridge, severe bone resorption with presence of basal bone only, and absence of vestibule. Initially, treatment consisted of the placement of a mandibular overdenture, supported on three implants in the anterior inter-foramen region, as the left implant was transfixed in the basal bone of 2 to 3 millimeters. Eleven years later, another two implants were placed in the anterior area and an immediate load was performed up to the first molars, for the placement of an implant supported fixed. Throughout the entire treatment, meticulous maintenance was carried out, with follow-up for fourteen years, interrupted by the patient’s death. From the third month after the opening the three implants initially placed, the presence of keratinized mucosa, definition of the vestibule, maturation of the alveolar ridge and bone formation in the mento region were observed. It was concluded that good planning, allied to mastery of the technique and adequate maintenance were the prerequisites necessary for obtaining favorable results, success of the present case, and for the patient to have a better quality of life.

  12. Nanotechnology for dental implants.

    Science.gov (United States)

    Tomsia, Antoni P; Lee, Janice S; Wegst, Ulrike G K; Saiz, Eduardo

    2013-01-01

    With the advent of nanotechnology, an opportunity exists for the engineering of new dental implant materials. Metallic dental implants have been successfully used for decades, but they have shortcomings related to osseointegration and mechanical properties that do not match those of bone. Absent the development of an entirely new class of materials, faster osseointegration of currently available dental implants can be accomplished by various surface modifications. To date, there is no consensus regarding the preferred method(s) of implant surface modification, and further development will be required before the ideal implant surface can be created, let alone become available for clinical use. Current approaches can generally be categorized into three areas: ceramic coatings, surface functionalization, and patterning on the micro- to nanoscale. The distinctions among these are imprecise, as some or all of these approaches can be combined to improve in vivo implant performance. These surface improvements have resulted in durable implants with a high percentage of success and long-term function. Nanotechnology has provided another set of opportunities for the manipulation of implant surfaces in its capacity to mimic the surface topography formed by extracellular matrix components of natural tissue. The possibilities introduced by nanotechnology now permit the tailoring of implant chemistry and structure with an unprecedented degree of control. For the first time, tools are available that can be used to manipulate the physicochemical environment and monitor key cellular events at the molecular level. These new tools and capabilities will result in faster bone formation, reduced healing time, and rapid recovery to function.

  13. Ion implantation for microelectronics

    International Nuclear Information System (INIS)

    Dearnaley, G.

    1977-01-01

    Ion implantation has proved to be a versatile and efficient means of producing microelectronic devices. This review summarizes the relevant physics and technology and assesses the advantages of the method. Examples are then given of widely different device structures which have been made by ion implantation. While most of the industrial application has been in silicon, good progress continues to be made in the more difficult field of compound semiconductors. Equipment designed for the industrial ion implantation of microelectronic devices is discussed briefly. (Auth.)

  14. Optimization of dental implantation

    Science.gov (United States)

    Dol, Aleksandr V.; Ivanov, Dmitriy V.

    2017-02-01

    Modern dentistry can not exist without dental implantation. This work is devoted to study of the "bone-implant" system and to optimization of dental prostheses installation. Modern non-invasive methods such as MRI an 3D-scanning as well as numerical calculations and 3D-prototyping allow to optimize all of stages of dental prosthetics. An integrated approach to the planning of implant surgery can significantly reduce the risk of complications in the first few days after treatment, and throughout the period of operation of the prosthesis.

  15. Thyroid storm with multiple organ failure, disseminated intravascular coagulation, and stroke with a normal serum FT3 level.

    Science.gov (United States)

    Harada, Yuko; Akiyama, Hisanao; Yoshimoto, Tatsuji; Urao, Yasuko; Ryuzaki, Munekazu; Handa, Michiko

    2012-01-01

    Thyroid storm is a rare disorder with a sudden onset, rapid progression and high mortality. We experienced a case of thyroid storm which had a devastating course, including multiple organ failure (MOF), severe hypoglycemia, disseminated intravascular coagulation (DIC), and stroke. It was difficult to make a diagnosis of thyroid storm in the present patient, because she did not have a history of thyroid disease and her serum FT3 level was normal. Clinicians should be aware that thyroid storm can occur even when there is an almost normal level of thyroid hormones, and that intensive anticoagulation is required for patients with atrial fibrillation to prevent stroke after thyroid storm.

  16. Novel approach to epicardial pacemaker implantation in patients with limited venous access.

    Science.gov (United States)

    Costa, Roberto; Scanavacca, Mauricio; da Silva, Kátia Regina; Martinelli Filho, Martino; Carrillo, Roger

    2013-11-01

    Limited venous access in certain patients increases the procedural risk and complexity of conventional transvenous pacemaker implantation. The purpose of this study was to determine a minimally invasive epicardial approach using pericardial reflections for dual-chamber pacemaker implantation in patients with limited venous access. Between June 2006 and November 2011, 15 patients underwent epicardial pacemaker implantation. Procedures were performed through a minimally invasive subxiphoid approach and pericardial window with subsequent fluoroscopy-assisted lead placement. Mean patient age was 46.4 ± 15.3 years (9 male [(60.0%], 6 female [40.0%]). The new surgical approach was used in patients determined to have limited venous access due to multiple abandoned leads in 5 (33.3%), venous occlusion in 3 (20.0%), intravascular retention of lead fragments from prior extraction in 3 (20.0%), tricuspid valve vegetation currently under treatment in 2 (13.3%), and unrepaired intracardiac defects in 2 (13.3%). All procedures were successful with no perioperative complications or early deaths. Mean operating time for isolated pacemaker implantation was 231.7 ± 33.5 minutes. Lead placement on the superior aspect of right atrium, through the transverse sinus, was possible in 12 patients. In the remaining 3 patients, the atrial lead was implanted on the left atrium through the oblique sinus, the postcaval recess, or the left pulmonary vein recess. None of the patients displayed pacing or sensing dysfunction, and all parameters remained stable throughout the follow-up period of 36.8 ± 25.1 months. Epicardial pacemaker implantation through pericardial reflections is an effective alternative therapy for those patients requiring physiologic pacing in whom venous access is limited. © 2013 Heart Rhythm Society. All rights reserved.

  17. Breast Reconstruction with Implants

    Science.gov (United States)

    ... your surgical options and discuss the advantages and disadvantages of implant-based reconstruction, and may show you ... Policy Notice of Privacy Practices Notice of Nondiscrimination Advertising Mayo Clinic is a not-for-profit organization ...

  18. Ion Implantation of Polymers

    DEFF Research Database (Denmark)

    Popok, Vladimir

    2012-01-01

    The current paper presents a state-of-the-art review in the field of ion implantation of polymers. Numerous published studies of polymers modified by ion beams are analysed. General aspects of ion stopping, latent track formation and changes of structure and composition of organic materials...... are discussed. Related to that, the effects of radiothermolysis, degassing and carbonisation are considered. Specificity of depth distributions of implanted into polymers impurities is analysed and the case of high-fluence implantation is emphasised. Within rather broad topic of ion bombardment, the focus...... is put on the low-energy implantation of metal ions causing the nucleation and growth of nanoparticles in the shallow polymer layers. Electrical, optical and magnetic properties of metal/polymer composites are under the discussion and the approaches towards practical applications are overviewed....

  19. Precipitation processes in implanted materials

    International Nuclear Information System (INIS)

    Borders, J.A.

    1978-01-01

    Ion implantation is a nonequilibrium process. It is possible to implant materials with impurities to concentration levels which exceed the solid solubilities. The return of the system to thermodynamic equilibrium is often accomplished by precipitation of the implanted species or a compound involving atoms of both the host and the implanted species. This may involve long time scales when taking place at room temperature or it may take place during the implantation

  20. High grade primary adrenal intravascular large B-cell lymphoma manifesting as Addison disease Linfoma intravascular de alto grado de células B grandes y origen suprarrenal que se manifiesta en forma de enfermedad de Addison

    Directory of Open Access Journals (Sweden)

    J. Venizelos

    2007-08-01

    Full Text Available We report a rare case of a 68 aged male who presented with adrenal failure and was diagnosed of high grade large B-cell lymphoma primarily arising in the adrenal glands. The patient was administrated with additional chemotherapy but he passed away 7 months later due to infection in the lungs. Intravascular lymphoma should be suspected in patients with bilateral adrenal masses who present with rapidly progressive adrenal insufficiency.Publicamos el caso poco frecuente de un varón de 68 años de edad que debutó con insuficiencia adrenal y fue diagnosticado de linfoma de alto grado de células B grandes ubicado principalmente en las glándulas suprarrenales. Al paciente le administraron quimioterapia adicional, pero falleció 7 meses después de infección pulmonar. El linfoma intravascular debe sospecharse en los pacientes con masas suprarrenales bilaterales que presenten insuficiencia adrenal rápidamente progresiva.

  1. A psicanálise e o dispositivo diferença sexual Psychoanalysis and the sexual difference device

    Directory of Open Access Journals (Sweden)

    Márcia Arán

    2009-12-01

    Full Text Available Diante da nova cartografia das relações entre gêneros e das sexualidades na cultura contemporânea, pretendemos discutir em que medida a psicanálise se apresenta como mais um dispositivo da sexualidade tal como concebido por Foucault, o qual procura reinstaurar o modelo tradicional da diferença sexual, através da reiteração da norma heterossexual da dominação masculina. Além disso, indagamos ainda em que medida a psicanálise pode permanecer como uma teoria crítica e uma prática clínica que permita uma relação produtiva com as novas configurações de gênero no contemporâneo, abrindo brechas para a concepção de novas formas de subjetivação. Com esse objetivo analisaremos o debate psicanalítico sobre 1 os deslocamentos do feminino e a positivação da feminilidade; 2 o casamento homossexual e a homoparentalidade e 3 a clínica da transexualidadeBefore the new cartography of gender relationships and sexualities in contemporary culture, we intend to discuss in which way psychoanalysis presents itself as one of the devices of sexuality as conceived by Foucault, which tries to reinstate the traditional model of sexual difference trough the reiteration of the heterosexual norm of male domination. Furthermore, we inquire how psychoanalysis can remain a critical theory and a clinical practice that allow a productive relationship with the new configurations of gender, which disclose the conception of new forms of subjectivity. With this aim, we will analyze the psychoanalytical debate on (1 the displacements of feminine and the positiveness of femininity; (2 the homosexual marriage and the homoparentality; and (3 the clinics of transsexuality

  2. El uso de dispositivos móviles por niños: entre el consumo y el cuidado familiar

    Directory of Open Access Journals (Sweden)

    Fernanda Carrasco Rivas

    2017-07-01

    Full Text Available Este artículo presenta los resultados de una investigación orientada a la comprensión de los intereses, expectativas y conflictos sociales que surgen en torno al uso de tecnologías móviles por parte de niños. Desde un enfoque crítico, se entiende la tecnología como una instrumentalización de intereses sociales en disputa: por una parte, los intereses dominantes que el mercado y el consumo establecen y, por otra, las expectativas familiares en torno a la comunicación y el cuidado familiar. Durante el año 2015 se desarrolló un estudio de casos a partir de la vinculación con estudiantes y apoderados de un curso de Cuarto básico de una escuela municipal de la ciudad de Temuco, Chile, y en el cual se implementaron grupos de discusión, entrevistas en profundidad y otras técnicas de investigación adaptadas al trabajo con niños. El análisis se orientó hacia la comprensión de las experiencias de uso, normas sociales, cambios, conflictos y expectativas familiares asociados con los dispositivos móviles. Se concluye reflexionando sobre la relevancia que la comprensión de fenómenos tecnológicos tiene para el trabajo social, en este caso, especialmente para el trabajo con familias, y se desarrollan propuestas generales de política pública adaptadas al caso chileno.

  3. Ion implantation for semiconductors

    International Nuclear Information System (INIS)

    Grey-Morgan, T.

    1995-01-01

    Full text: Over the past two decades, thousands of particle accelerators have been used to implant foreign atoms like boron, phosphorus and arsenic into silicon crystal wafers to produce special embedded layers for manufacturing semiconductor devices. Depending on the device required, the atomic species, the depth of implant and doping levels are the main parameters for the implantation process; the selection and parameter control is totally automated. The depth of the implant, usually less than 1 micron, is determined by the ion energy, which can be varied between 2 and 600 keV. The ion beam is extracted from a Freeman or Bernas type ion source and accelerated to 60 keV before mass analysis. For higher beam energies postacceleration is applied up to 200 keV and even higher energies can be achieved by mass selecting multiplycharged ions, but with a corresponding reduction in beam output. Depending on the device to be manufactured, doping levels can range from 10 10 to 10 15 atoms/cm 2 and are controlled by implanter beam currents in the range up to 30mA; continuous process monitoring ensures uniformity across the wafer of better than 1 % . As semiconductor devices get smaller, additional sophistication is required in the design of the implanter. The silicon wafers charge electrically during implantation and this charge must be dissipated continuously to reduce the electrical stress in the device and avoid destructive electrical breakdown. Electron flood guns produce low energy electrons (below 10 electronvolts) to neutralize positive charge buildup and implanter design must ensure minimum contamination by other isotopic species and ensure low internal sputter rates. The pace of technology in the semiconductor industry is such that implanters are being built now for 256 Megabit circuits but which are only likely to be widely available five years from now. Several specialist companies manufacture implanter systems, each costing around US$5 million, depending on the

  4. Quantitative ion implantation

    International Nuclear Information System (INIS)

    Gries, W.H.

    1976-06-01

    This is a report of the study of the implantation of heavy ions at medium keV-energies into electrically conducting mono-elemental solids, at ion doses too small to cause significant loss of the implanted ions by resputtering. The study has been undertaken to investigate the possibility of accurate portioning of matter in submicrogram quantities, with some specific applications in mind. The problem is extensively investigated both on a theoretical level and in practice. A mathematical model is developed for calculating the loss of implanted ions by resputtering as a function of the implanted ion dose and the sputtering yield. Numerical data are produced therefrom which permit a good order-of-magnitude estimate of the loss for any ion/solid combination in which the ions are heavier than the solid atoms, and for any ion energy from 10 to 300 keV. The implanted ion dose is measured by integration of the ion beam current, and equipment and techniques are described which make possible the accurate integration of an ion current in an electromagnetic isotope separator. The methods are applied to two sample cases, one being a stable isotope, the other a radioisotope. In both cases independent methods are used to show that the implantation is indeed quantitative, as predicted. At the same time the sample cases are used to demonstrate two possible applications for quantitative ion implantation, viz. firstly for the manufacture of calibration standards for instrumental micromethods of elemental trace analysis in metals, and secondly for the determination of the half-lives of long-lived radioisotopes by a specific activity method. It is concluded that the present study has advanced quantitative ion implantation to the state where it can be successfully applied to the solution of problems in other fields

  5. Ion implantation - an introduction

    International Nuclear Information System (INIS)

    Townsend, P.D.

    1986-01-01

    Ion implantation is a widely used technique with a literature that covers semiconductor production, surface treatments of steels, corrosion resistance, catalysis and integrated optics. This brief introduction outlines advantages of the technique, some aspects of the underlying physics and examples of current applications. Ion implantation is already an essential part of semiconductor technology while in many other areas it is still in an early stage of development. The future scope of the subject is discussed. (author)

  6. Contraceptive implants: current perspectives

    Directory of Open Access Journals (Sweden)

    Rowlands S

    2014-09-01

    Full Text Available Sam Rowlands,1,2 Stephen Searle3 1Centre of Postgraduate Medical Research and Education, School of Health and Social Care, Bournemouth University, Bournemouth, United Kingdom; 2Dorset HealthCare, Bournemouth, United Kingdom; 3Sexual Health Services, Chesterfield, United KingdomAbstract: Progestin-only contraceptive implants are a highly cost-effective form of long-acting reversible contraception. They are the most effective reversible contraceptives and are of a similar effectiveness to sterilization. Pregnancies are rare in women using this method of contraception, and those that do occur must be fully investigated, with an ultrasound scan of the arm and serum etonogestrel level if the implant cannot be located. There are very few contraindications to use of implants, and they have an excellent safety profile. Both acceptability and continuation with the method are high. Noncontraceptive benefits include improvements in dysmenorrhea, ovulatory pain, and endometriosis. Problematic bleeding is a relatively common adverse effect that must be covered in preinsertion information-giving and supported adequately if it occurs. Recognized training for both insertion and removal should be undertaken. Care needs to be taken at both insertion and removal to avoid neurovascular injury. Implants should always be palpable; if they are not, noninsertion should be assumed until disproven. Etonogestrel implants are now radiopaque, which aids localization. Anticipated difficult removals should be performed by specially trained experts. Keywords: contraceptive, subdermal implant, etonogestrel, levonorgestrel, progestin-only, long-acting reversible contraception

  7. Anodized dental implant surface

    Directory of Open Access Journals (Sweden)

    Sunil Kumar Mishra

    2017-01-01

    Full Text Available Purpose: Anodized implants with moderately rough surface were introduced around 2000. Whether these implants enhanced biologic effect to improve the environment for better osseointegration was unclear. The purpose of this article was to review the literature available on anodized surface in terms of their clinical success rate and bone response in patients till now. Materials and Methods: A broad electronic search of MEDLINE and PubMed databases was performed. A focus was made on peer-reviewed dental journals. Only articles related to anodized implants were included. Both animal and human studies were included. Results: The initial search of articles resulted in 581 articles on anodized implants. The initial screening of titles and abstracts resulted in 112 full-text papers; 40 animal studies, 16 studies on cell adhesion and bacterial adhesion onto anodized surfaced implants, and 47 human studies were included. Nine studies, which do not fulfill the inclusion criteria, were excluded. Conclusions: The long-term studies on anodized surface implants do favor the surface, but in most of the studies, anodized surface is compared with that of machined surface, but not with other surfaces commercially available. Anodized surface in terms of clinical success rate in cases of compromised bone and immediately extracted sockets has shown favorable success.

  8. Plasma source ion implantation

    International Nuclear Information System (INIS)

    Conrad, J.R.; Forest, C.

    1986-01-01

    The authors' technique allows the ion implantation to be performed directly within the ion source at higher currents without ion beam extraction and transport. The potential benefits include greatly increased production rates (factors of 10-1000) and the ability to implant non-planar targets without rastering or shadowing. The technique eliminates the ion extractor grid set, beam raster equipment, drift space and target manipulator equipment. The target to be implanted is placed directly within the plasma source and is biased to a large negative potential so that plasma ions gain energy as they accelerate through the potential drop across the sheath that forms at the plasma boundary. Because the sheath surrounds the target on all sides, all surfaces of the target are implanted without the necessity to raster the beam or to rotate the target. The authors have succeeded in implanting nitrogen ions in a silicon target to the depths and concentrations required for surface treatment of materials like stainless steel and titanium alloys. They have performed ESCA measurements of the penetration depth profile of a silicon target that was biased to 30 kV in a nitrogen discharge plasma. Nitrogen ions were implanted to a depth of 700A at a peak concentration of 30% atomic. The measured profile is quite similar to a previously obtained profile in titanium targets with conventional techniques

  9. Short dental implants: an emerging concept in implant treatment.

    Science.gov (United States)

    Al-Hashedi, Ashwaq Ali; Taiyeb Ali, Tara Bai; Yunus, Norsiah

    2014-06-01

    Short implants have been advocated as a treatment option in many clinical situations where the use of conventional implants is limited. This review outlines the effectiveness and clinical outcomes of using short implants as a valid treatment option in the rehabilitation of edentulous atrophic alveolar ridges. Initially, an electronic search was performed on the following databases: Medline, PubMed, Embase, Cochrane Database of Systematic Reviews, and DARE using key words from January 1990 until May 2012. An additional hand search was included for the relevant articles in the following journals: International Journal of Oral and Maxillofacial Implants, Clinical Oral Implants Research, Journal of Clinical Periodontology, International Journal of Periodontics, Journal of Periodontology, and Clinical Implant Dentistry and Related Research. Any relevant papers from the journals' references were hand searched. Articles were included if they provided detailed data on implant length, reported survival rates, mentioned measures for implant failure, were in the English language, involved human subjects, and researched implants inserted in healed atrophic ridges with a follow-up period of at least 1 year after implant-prosthesis loading. Short implants demonstrated a high rate of success in the replacement of missing teeth in especially atrophic alveolar ridges. The advanced technology and improvement of the implant surfaces have encouraged the success of short implants to a comparable level to that of standard implants. However, further randomized controlled clinical trials and prospective studies with longer follow-up periods are needed.

  10. Evaluation of Directional Atherectomy Studied by Intravascular Ultrasound in Femoropopliteal Artery Stenosis

    International Nuclear Information System (INIS)

    Tielbeek, Alexander V.; Vroegindeweij, Dammis; Gussenhoven, Elma J.; Buth, Jacob; Landman, Guido H.M.

    1997-01-01

    Purpose: To evaluate the role of intravascular ultrasound (IVUS) before and after directional atherectomy (DA) in the treatment of femoropopliteal artery stenosis. Methods: In 12 patients with 16 stenoses IVUS was performed before and immediately after an angiographically successful DA. This was defined as a diameter reduction (DR) ≤ 50%, which was calculated using the minimal lumen diameter compared with the diameter of a nearby 'normal' segment. In the presence of residual plaque on IVUS an additional DA was performed. Endpoints studied were DR ≤ 30% on IVUS compared with the IVUS findings of the angiographically normal reference segment, or when no additional atherosclerotic material could be removed by further DA passages. Results: Additional DA (mean 1.6 per lesion) had to be performed in all patients. Initial DA increased the cross-sectional free lumen area (FLA) from 3.8 ± 2.0 mm 2 to 8.1 ± 2.7 mm 2 (p= 0.0004). Additional DA increased FLA to 9.3 ± 2.3 mm 2 (p= 0.002) after the second passage and to 9.8 ± 2.4 mm 2 (p= 0.09) after the final DA run. The plaque area (PLA) before DA decreased from 18.1 ± 4.2 mm 2 to 15.4 ± 4.8 mm 2 (p= 0.002) after the first passage, and to 13.5 ± 5.0 mm 2 (p= 0.004) and 12.8 ± 4.4 mm 2 (p= 0.07) after the second and final DA runs, respectively. PLA of the reference segment (9.5 ± 5.7 mm 2 ) was significantly smaller (p= 0.006) than the final PLA of the treated lesion, indicating a large amount of retained plaque. As a result of DA there was an increase in the area bordered by the medial layer, i.e., the total vessel area (from 21.9 ± 4.7 mm 2 to 23.0 ± 4.7 mm 2 ), significantly in eccentric and soft lesions. On IVUS, dissection and plaque rupture after the final passage was seen in 12 of 16 stenoses; two dissections were seen on the completion angiogram. After the final passage in all stenoses except three, the DR with IVUS was ≤ 30%. Conclusion: Lumen enlargement following DA is predominantly due to plaque

  11. Imaging findings of intravascular papillary endothelial hyperplasia presenting in extremities: correlation with pathological findings.

    Science.gov (United States)

    Lee, Sun Joo; Choo, Hye Jung; Park, Ji Sung; Park, Yeong-Mi; Eun, Choong Ki; Hong, Sung Hwan; Hwang, Ji Young; Lee, In Sook; Lee, Jongmin; Jung, Soo-Jin

    2010-08-01

    To describe magnetic resonance imaging (MRI) and ultrasound (US) findings of intravascular papillary endothelial hyperplasia (IPEH) arising in extremities. Six patients with IPEH confirmed by surgical resection were reviewed retrospectively. Before resection, 3 patients underwent both MRI and US and 3 patients underwent only MRI. Two radiologists retrospectively reviewed MR/US imaging results and correlated them with pathological features. The 6 IPEHs were diagnosed as 4 mixed forms and 2 pure forms. The pre-existing pathology of four mixed forms was intramuscular or intermuscular hemangioma. By MRI, the mixed form of IPEH (n = 4) revealed iso- to slightly high signal intensity containing nodule-like foci of high signal intensity on T1-weighted images (T1WI) and high signal intensity-containing nodule-like foci of low signal intensity on T2-weighted images (T2WI). The pure form of IPEH (n = 2) showed homogeneous iso- signal intensity on T1WI and high and low signal intensity containing nodule-like foci of low signal intensity on T2WI. On gadolinium-enhanced fat-suppressed T1WI, 50% of cases (n = 3: mixed forms) revealed peripheral, septal, and central enhancement. The other IPEHs (n = 3: 1 mixed and 2 pure forms) showed peripheral and septal enhancement or only peripheral enhancement. By US, two mixed forms of IPEH showed well-defined hypoechoic masses containing hyperechoic septa and central portion with vascularities. One pure form of IPEH was a homogeneous hypoechoic mass with septal and peripheral vascularities on color Doppler imaging. The foci of high signal intensity on T1WI, foci of low signal intensity on T2WI, and non-enhancing portions on MRI and the hypoechoic portion on US were histopathologically correlated with thrombi and the peripheral/septal or central enhancing areas on MRI, hyperechoic septa and the central portion on US, and septal/central or peripheral vascularities on color Doppler imaging corresponded to hypertrophic papillary epithelium and

  12. Imaging findings of intravascular papillary endothelial hyperplasia presenting in extremities: correlation with pathological findings

    International Nuclear Information System (INIS)

    Lee, Sun Joo; Choo, Hye Jung; Park, Ji Sung; Park, Yeong-Mi; Eun, Choong Ki; Hong, Sung Hwan; Hwang, Ji Young; Lee, In Sook; Lee, Jongmin; Jung, Soo-Jin

    2010-01-01

    To describe magnetic resonance imaging (MRI) and ultrasound (US) findings of intravascular papillary endothelial hyperplasia (IPEH) arising in extremities. Six patients with IPEH confirmed by surgical resection were reviewed retrospectively. Before resection, 3 patients underwent both MRI and US and 3 patients underwent only MRI. Two radiologists retrospectively reviewed MR/US imaging results and correlated them with pathological features. The 6 IPEHs were diagnosed as 4 mixed forms and 2 pure forms. The pre-existing pathology of four mixed forms was intramuscular or intermuscular hemangioma. By MRI, the mixed form of IPEH (n = 4) revealed iso- to slightly high signal intensity containing nodule-like foci of high signal intensity on T1-weighted images (T1WI) and high signal intensity-containing nodule-like foci of low signal intensity on T2-weighted images (T2WI). The pure form of IPEH (n = 2) showed homogeneous iso- signal intensity on T1WI and high and low signal intensity containing nodule-like foci of low signal intensity on T2WI. On gadolinium-enhanced fat-suppressed T1WI, 50% of cases (n = 3: mixed forms) revealed peripheral, septal, and central enhancement. The other IPEHs (n = 3: 1 mixed and 2 pure forms) showed peripheral and septal enhancement or only peripheral enhancement. By US, two mixed forms of IPEH showed well-defined hypoechoic masses containing hyperechoic septa and central portion with vascularities. One pure form of IPEH was a homogeneous hypoechoic mass with septal and peripheral vascularities on color Doppler imaging. The foci of high signal intensity on T1WI, foci of low signal intensity on T2WI, and non-enhancing portions on MRI and the hypoechoic portion on US were histopathologically correlated with thrombi and the peripheral/septal or central enhancing areas on MRI, hyperechoic septa and the central portion on US, and septal/central or peripheral vascularities on color Doppler imaging corresponded to hypertrophic papillary epithelium and

  13. Análise da distribuição das tensões nas estruturas de suporte de overdentures, rebordo residual e implantes, com sistema de conexão de coroas cônicas (Syncone-Dentsply).

    OpenAIRE

    Ana Cristina Aurora Rosa Perasso Guariglia

    2007-01-01

    O sistema de osseointegração desenvolvido por Branemark revolucionou o campo das reabilitações protéticas, incentivando os profissionais a indicar e realizar próteses do tipo overdentures. Estes dispositivos representam uma ótima alternativa para solucionar os problemas dos pacientes desdentados, insatisfeitos por diversos fatores. Várias são as associações entre os implantes e os sistemas de conexões empregados em overdentures. A literatura e a prática clínica fazem observar que na dependênc...

  14. Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis.

    Science.gov (United States)

    Sallin, Michelle A; Sakai, Shunsuke; Kauffman, Keith D; Young, Howard A; Zhu, Jinfang; Barber, Daniel L

    2017-03-28

    Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore, we examined the role of Th1-polarizing factors in the generation of protective and non-protective subsets of Mtb-specific Th1 cells. We find that IL-12/23p40 promotes Th1 cell expansion and maturation beyond the CD73 + CXCR3 + T-bet dim stage, and T-bet prevents deviation of Th1 cells into Th17 cells. Nevertheless, IL- 12/23p40 and T-bet are also essential for the production of a prominent subset of intravascular CX3CR1 + KLRG1 + Th1 cells that persists poorly and can neither migrate into the lung parenchyma nor control Mtb growth. Furthermore, T-bet suppresses development of CD69 + CD103 + tissue resident phenotype effectors in lung. In contrast, Th1-cell-derived IFN-γ inhibits the accumulation of intravascular CX3CR1 + KLRG1 + Th1 cells. Thus, although IL-12 and T-bet are essential host survival factors, they simultaneously oppose lung CD4 T cell responses at several levels, demonstrating the dual nature of Th1 polarization in tuberculosis. Published by Elsevier Inc.

  15. Th1 Differentiation Drives the Accumulation of Intravascular, Non-protective CD4 T Cells during Tuberculosis

    Directory of Open Access Journals (Sweden)

    Michelle A. Sallin

    2017-03-01

    Full Text Available Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore, we examined the role of Th1-polarizing factors in the generation of protective and non-protective subsets of Mtb-specific Th1 cells. We find that IL-12/23p40 promotes Th1 cell expansion and maturation beyond the CD73+CXCR3+T-betdim stage, and T-bet prevents deviation of Th1 cells into Th17 cells. Nevertheless, IL- 12/23p40 and T-bet are also essential for the production of a prominent subset of intravascular CX3CR1+KLRG1+ Th1 cells that persists poorly and can neither migrate into the lung parenchyma nor control Mtb growth. Furthermore, T-bet suppresses development of CD69+CD103+ tissue resident phenotype effectors in lung. In contrast, Th1-cell-derived IFN-γ inhibits the accumulation of intravascular CX3CR1+KLRG1+ Th1 cells. Thus, although IL-12 and T-bet are essential host survival factors, they simultaneously oppose lung CD4 T cell responses at several levels, demonstrating the dual nature of Th1 polarization in tuberculosis.

  16. Disseminated intravascular coagulopathy caused by Kikuchi–Fujimoto disease resulting in death: first case report in Turkey

    Directory of Open Access Journals (Sweden)

    Uslu E

    2014-02-01

    Full Text Available Emine Uslu,1 Sibel Gurbuz,2 Abdulsamet Erden,1 Fatma Aykas,1 Hatice Karagoz,1 Samet Karahan,1 Hatice Karaman,3 Ali Cetinkaya,1 Deniz Avci1 1Internal Medicine Department, 2Infection Disease Department, 3Clinical Pathology Department, Kayseri Training and Research Hospital, Kayseri, Turkey Abstract: Kikuchi disease, also called Kikuchi–Fujimoto disease or Kikuchi's histiocytic necrotizing lymphadenitis, is a rare, benign condition of unknown cause, usually characterized by cervical lymphadenopathy and fever. The diagnosis is based on histopathology. Our patient was a woman with bilateral cervical lymphadenopathy, fever, chest and abdominal pain, fatigue, maculopapular rash on her face, trunk, and upper and lower extremities. Immunological and rheumatological tests were negative. We took a cervical lymph node biopsy that showed a proliferative and necrotizing process centered in the paracortex characterized by patchy circumscribed or confluent areas of necrosis associated with karyorrhexis, and was remarkable by the absence of granulocytes and the paucity of plasma cells. These findings confirmed the diagnosis of Kikuchi's disease. The patient's hemoglobin values decreased, and the peripheral blood smear revealed schistocytes. Blood tests showed raised D-dimer, activated partial thromboplastin time, prothrombin time, and international normalized ratio with decreased fibrinogen. The patient's condition quickly worsened and disseminated intravascular coagulopathy eventually developed. Her initial management consisted of a corticosteroid and hydroxychloroquine. Keywords: disseminated intravascular coagulopathy, Kikuchi–Fujimoto disease, necrotizing lymphadenitis

  17. Dynamic magnetic resonance angiography of the arteries of the hand. A comparison between an extracellular and an intravascular contrast agent

    International Nuclear Information System (INIS)

    Reisinger, Clemens; Gluecker, Thomas; Jacob, Augustinus Ludwig; Bongartz, Georg; Bilecen, Deniz

    2009-01-01

    The purpose of this study was to compare the image quality of the intravascular contrast agent gadofosveset with the extracellular contrast agent gadoterate meglumine in time-resolved three-dimensional magnetic resonance (MR) angiography of the human arteries of the hand. The value of cuff compression technique for suppression of venous enhancement for both contrast agents was also investigated. Three-dimensional MR angiograms of both hands of 11 healthy volunteers were acquired for each contrast agent at 1.5-T, while subsystolic cuff compression was applied at one side. Quantitative and qualitative evaluation were performed and analyzed with Student's t-test. Visualization of vessels was superior in the images acquired with gadofosveset, especially in the late phases. Quantitative and qualitative evaluation showed significantly higher values for gadofosveset. The cuff compression at the lower arm proved to be an effective method to enhance arterial vessels. In conclusion the blood pool agent gadofosveset is superior for the dynamic imaging of the vessels of the hand when compared with the extracellular contrast agent gadoterate meglumine. To fully utilize the advantages of intravascular contrast agents, venous overlay has to be delayed or reduced, which can be achieved effectively by subsystolic lower arm cuff compression. (orig.)

  18. Pulmonary artery intravascular abscess: A rare complication of incomplete infective endocarditis treatment in the setting of injection drug use

    Directory of Open Access Journals (Sweden)

    Simran Gupta

    Full Text Available Infective endocarditis (IE is a serious complication of injection drug use. Right-sided IE encompasses 5–10% of all IE cases, with the majority involving the tricuspid valve (TV. The predominant causal organism is Staphylococcus aureus. Most cases of right-sided IE can be successfully treated with antimicrobials, but approximately 5–16% require eventual surgical intervention. We report the case of a 36-year-old female with active injection drug use who developed methicillin-sensitive Staphylococcus aureus IE of the tricuspid valve. Associated with poor adherence to medical therapy as a consequence of opioid addiction, she developed septic emboli to the lungs and an intravascular abscess in the left main pulmonary artery. These long-term potentially fatal, sequelae of incompletely treated IE require surgical intervention, as medical therapy is unlikely to be sufficient. Surgical management may involve TV replacement, pulmonary artery resection, and pneumonectomy. Prevention of these complications may have been achieved by concurrent opioid addiction therapy. An intravascular pulmonary artery abscess is a novel complication of advanced IE that has not been previously reported. This complication likely arose due to incomplete IE treatment as a consequence of opioid addiction, highlighting the need for concurrent addiction management. Intravenous antimicrobial therapy is likely not adequate, and surgical intervention, including pulmonary artery resection and pneumonectomy may be necessary. Keywords: Pulmonary artery abscess, Infective endocarditis, Injection drug use, Opioid use disorder

  19. Th1 differentiation drives the accumulation of intravascular, non-protective CD4 T cells during tuberculosis

    Science.gov (United States)

    Sallin, Michelle A.; Sakai, Shunsuke; Kauffman, Keith D.; Young, Howard A.; Zhu, Jinfang; Barber, Daniel L.

    2017-01-01

    SUMMARY Recent data indicate that the differentiation state of Th1 cells determines their protective capacity against tuberculosis. Therefore, we examined the role of Th1 polarizing factors in the generation of protective and non-protective subsets of Mtb-specific Th1 cells. We find IL-12/23p40 promotes Th1 cell expansion and maturation beyond the CD73+CXCR3+T-betdim stage, and T-bet prevents deviation of Th1 cells into Th17 cells. Nevertheless, IL-12/23p40 and T-bet are also essential for the production of a prominent subset of intravascular CX3CR1+KLRG1+ Th1 cells that persists poorly and can neither migrate into the lung parenchyma nor control Mtb growth. Furthermore, T-bet suppresses development of CD69+CD103+ tissue resident phenotype effectors in lung. In contrast, Th1 cell-derived IFNγ inhibits the accumulation of intravascular CX3CR1+KLRG1+ Th1 cells. Thus, although IL-12 and T-bet are essential host survival factors, they simultaneously oppose lung CD4 T cell responses at several levels, demonstrating the dual nature of Th1 polarization in tuberculosis. PMID:28355562

  20. Coagulación de la leche. Desarrollo de un dispositivo para el “monitoreo” online del proceso. Avances en la Argentina

    Directory of Open Access Journals (Sweden)

    REVELLI, G.R.2

    2012-08-01

    Full Text Available La coagulación enzimática de la leche es una etapa fundamental en la elaboración de queso. Su controlonline tiene por objeto la determinación del tiempo de coagulación, la velocidad de crecimiento de la firmeza yel apropiado tiempo de corte de la cuajada. El tratamiento térmico de la leche permite incorporar al queso proteínasdel suero para incrementar su valor biológico y su rendimiento. También, numerosas investigacionesreportan el agregado de Proteínas de Suero en Polvo (WPC en la elaboración de distintos tipos de quesos.Tratamientos diversos de las proteínas del suero son utilizados para alimentos ricos en almidones. El desarrollode un dispositivo que cumpla con los requerimientos de fortaleza, higiene en el lugar, que no impida lasoperaciones de corte y agitación y que no sea destructivo, será una herramienta importante en el estudio delos efectos de las variables críticas, el control de la elaboración de queso y yogurt, y en el desarrollo de nuevosproductos. Una revisión histórica muestra que desde hace varias décadas los investigadores se preocupan por obtener dispositivos basados en diferentes métodos. En la Argentina, se reportan experiencias con utilización del principio del alambre caliente. En la actualidad, se construye un dispositivo innovador que puede seraplicado en el desarrollo de nuevos productos y en tina quesera industrial.

  1. Dispositivos educativos: campo de tensión en la relación entre infancias, filosofías y escuelas

    Directory of Open Access Journals (Sweden)

    María Belén Bedetti

    2015-01-01

    Full Text Available La noción de experiencia ha dado lugar a la distinción entre el programa Filosofía para Niños y la propuesta de Filosofía con niños: el primero hace referencia a la creación por especialistas de un curriculum estructurado, compuesto por novelas y manuales de apoyo al docente; el segundo, a la propuesta de trabajar con distinto tipo de materiales, pensados y escogidos libremente por cada docente para la indagación. En líneas generales suele considerarse que las facilidades del dispositivo lipmaniano han posibilitado su viabilidad; en contrapartida, frente a la reproducción de dispositivos didácticos, la planificación creativa de las sesiones de indagación filosófica permitiría la experiencia del reflexionar filosófico. Esta cuestión se analizará desde prácticas y experiencias específicas de acompañamiento a instituciones desde la siguiente tensión política: si las prácticas que vinculan filosofía e infancia anhelan ser mayoritarias, multiplicarse; o si, por el contrario, prefieren resignarse a un menor alcance al privilegiar determinados dispositivos por considerarlos como los únicos que garantizarían la experiencia, en el sentido de una transformación de sí en contextos de pensar situado. Análisis viabilizado por diversas reflexiones y categorías experienciales que emergen del trabajo en la formación de profesores de filosofía.

  2. Dispositivos educativos: campo de tensión en la relación entre infancias, filosofías y escuelas

    Directory of Open Access Journals (Sweden)

    María Belén Bedetti

    2015-01-01

    Full Text Available La noción de experiencia ha dado lugar a la distinción entre el programa Filosofía para Niños y la propuesta de Filosofía con niños : el primero hace referencia a la creación por especialistas de un curriculum estructurado, compuesto por nove- las y manuales de apoyo al docente; el segundo, a la propuesta de trabajar con distinto tipo de materiales, pensados y escogidos libremente por cada docente para la indagación. En líneas generales suele considerarse que las facilidades del dispositivo lipmaniano han posibilitado su viabilidad; en contrapartida, frente a la reproducción de dispositivos didácticos, la planificación creativa de las sesiones de indagación filosófica permitiría la experiencia del reflexionar filosófico. Esta cuestión se analizará desde prácticas y experiencias específicas de acompañamiento a instituciones desde la siguiente tensión política: si las prácticas que vinculan filosofía e infancia anhelan ser mayoritarias, multiplicar - se; o si, por el contrario, prefieren resignarse a un menor alcance al privilegiar determinados dispositivos por considerarlos como los únicos que garantizarían la experiencia, en el sentido de una transformación de sí en contextos de pensar situado. Análisis viabilizado por diversas reflexiones y categorías experienciales que emergen del trabajo en la formación de profesores de filosofía.

  3. GRUPO COMO DISPOSITIVO SOCIOEDUCATIVO: PESQUISA-INTERVENÇÃO COM ADOLESCENTES EM CUMPRIMENTO DE PRESTAÇÃO DE SERVIÇO À COMUNIDADE

    Directory of Open Access Journals (Sweden)

    Dayane Silva Rodrigues

    2018-01-01

    Full Text Available Este artigo apresenta discussões oriundas de uma tese de doutorado, que problematizou especificidades, princípios e estratégias para a utilização de metodologias grupais como dispositivos de atuação no atendimento a adolescentes que cumprem medidas socioeducativas em meio aberto. O estudo foi construído por meio de uma pesquisa-intervenção com onze adolescentes em cumprimento da medida socioeducativa de Prestação de Serviço à Comunidade, vinculados a uma unidade de atendimento do Distrito Federal. O artigo apresenta um recorte dos resultados da tese, evidenciando análises relativas às significações produzidas com os adolescentes sobre o conceito de trabalho, inerente à medida socioeducativa de prestação de serviço à comunidade. Sob o prisma da Psicologia Histórico-Cultural (L. S. Vigotski, da perspectiva do dialogismo (M. Bakthin e da problematização do conceito de grupo-dispositivo (R. B. Barros, são analisados os processos de negociação para a realização uma atividade colaborativa e comunitária com adolescentes. Na sequência, são abordados aspectos relativos aos movimentos do processo grupal, permeado por devires e ressignificações. Por fim, discute-se o conceito de grupo como dispositivo socioeducativo que pode ser tomado na execução de medidas socioeducativas, com vistas a ampliar as ferramentas de atendimento aos adolescentes e contribuir para o aprofundamento da base teórico-metodológica das práticas em socioeducação.

  4. DISPOSITIVOS MÉDICOS NO SISTEMA ÚNICO DE SAÚDE (SUS - AVALIAÇÃO E INCORPORAÇÃO TECNOLÓGICA

    Directory of Open Access Journals (Sweden)

    Murilo Contó

    2015-10-01

    Full Text Available A Avaliação de Tecnologias em Saúde (ATS, considerando todas as suas dimensões clínicas, sociais e econômicas envolvidas, possui relevância estratégica para subsidiar as decisões dos gestores para a incorporação, alteração ou exclusão de tecnologias nos sistemas de saúde. No que tange aos dispositivos médicos, a ATS deve considerar algumas particularidades aplicáveis exclusivamente a essas tecnologias. Este artigo apresenta o fluxo de incorporações de dispositivos médicos no Sistema Único de Saúde (SUS e apresenta alguns aspectos particulares, como curva de aprendizagem, procedimentos associados, necessidades de infraestrutura, tecnologia embracada e custo total de propriedade; a serem observados na documentação a ser preparada para apreciação na Comissão Nacional de Incoporação de Tecnologias no SUS (CONITEC. Tais aspectos podem ter influência direta tanto na variação dos custos relacionados às tecnologias como também na efetividade dos desfechos desejados. A observância destes aspectos numa ATS relacionada a dispositivos médicos permitirá que a incorporação possa avançar sob a ótica da eficiência com uma alocação de recursos mais precisa no SUS, assegurando ainda os resultados de efetividade esperados e a manutenção adequada das tecnologias por todo seu ciclo de vida. 

  5. Estudo de materiais, estruturas de dispositivos e fenômenos de transporte em sistemas fotovoltaicos híbridos orgânico-inorgânico

    OpenAIRE

    Adriana Pereira Ibaldo

    2010-01-01

    Recentemente tem sido observado grande avanço na área de fotovoltaicos orgânicos e híbridos. Esses dispositivos baseiam-se em diferenças de energia eletrônica nas interfaces dos componentes de uma heterojunção, onde as heterojunções dispersas obtidas via arranjos interpenetrantes com estes dois compostos, em dimensões sub-20-nm, permite coleção efetiva dos portadores de carga fotogerados, mesmo com pequeno comprimento de difusão do éxciton e baixa mobilidade dos portadores de carga. Desta man...

  6. Dispositivo y método para la síntesis de grafeno en polvo a partir de una fuente de carbono

    OpenAIRE

    Rincón, Rocío; Calzada Canalejo, María Dolores; Melero, Cristóbal

    2016-01-01

    La presente invención se encuadra en el campo de la producción de nanoestructuras de carbono y más especialmente se refiere a un procedimiento de síntesis de grafeno. Los autores de la invención han diseñado el dispositivo y desarrollado un procedimiento para la síntesis de grafeno en polvo a partir de la descomposición de una fuente de carbono por un plasma de microondas a presión atmosférica. El plasma se genera en el extremo de un vástago por el que circ...

  7. Herramienta para la extracción automática de metadatos en vídeos de dispositivos móviles

    OpenAIRE

    Esteban Cobo, Miguel

    2016-01-01

    Actualmente el número de cámaras fotográficas en dispositivos móviles crece a un ritmo imparable. Asimismo la calidad y prestaciones de las mismas hacen que sean de uso común, desbancando poco a poco a las Cámaras fotográficas digitales. Este escenario produce que el análisis forense de este tipo de vídeos cobre especial importancia y sea necesario y útil en multitud de situaciones (pruebas en casos judiciales, espionaje industrial, privación de la libertad de prensa, pederastia, etc). En est...

  8. 314. Extracción de dispositivos intracardíacos en pacientes sometidos previamente a procedimientos de cardiología intervencionista

    OpenAIRE

    E. Villagrán; L. Montes; Z. Garcés; A. Ayaon; M. Carnero; J. Silva; A. Alswies; J.E. Rodríguez

    2012-01-01

    Descripción de una cohorte de pacientes sometidos a la implantación de algún dispositivo intracardíaco percutáneo (DCIP) que finalmente fueron intervenidos quirúrgicamente por disfunción de los mismos. Material y métodos: Se analizó de forma retrospectiva toda la cohorte de pacientes sometidos a extracción de DCIP intervenidos en nuestro centro. Se describe la muestra de pacientes y se resumen los resultados quirúrgicos. Resultados: Desde julio de 2007 – julio de 2011, 25 pacientes inte...

  9. El dibujo como dispositivo pedagógico. Fundamentos del dibujo en la enseñanza contemporánea de las artes plásticas

    OpenAIRE

    RODRIGUES ESTEVES, PHILIP JOSÉ

    2012-01-01

    La presente disertación incide sobre las prácticas pedagógicas del dibujo en el contexto de la educación artística y pretende comprender las condiciones que hoy las caracterizan. El trabajo intenta fijar estas condiciones en el ámbito de una problemática que no es solamente la de la enseñanza del dibujo, sino también, y sobre todo, la de su aprendizaje. Comprender el dibujo como dispositivo pedagógico y, en particular, la importancia de los ejercicios en el aprendizaje del dibujo, exige pensa...

  10. Diseño conceptual del sistema portante para un sensor GPR en un dispositivo para detección de minas antipersona en Antioquia-Colombia

    OpenAIRE

    Gutiérrez Bolívar, Julián

    2011-01-01

    Resumen: Se presenta el estado del arte de las Minas Antipersona (MAPs) y Artefactos Explosivos Improvisados (AEIs), planteando estadísticas globales y nacionales, de las víctimas de estos artefactos explosivos que han resultado heridas, mutiladas o muertas. Se realiza y presenta una revisión de los proyectos desarrollados en Colombia y otros países, los cuales son enfocados al desarrollo de dispositivos para la detección de MAPs, AEIs y otros tipos de minas. Se realiza una búsqueda de publi...

  11. Desenvolvimento de uma interface gráfica e de uma base de dados para um dispositivo médico de electrosterapia

    OpenAIRE

    Pereira, Carlos Miguel Brandão

    2011-01-01

    A engenharia biomédica tem evoluído significativamente nas soluções que apresenta, integrando software médico, para o serviço de cuidados de saúde contribuindo, assim, para o aumento da qualidade de vida da população. Este projecto tem como objecto principal a criação de uma interface gráfica de controlo contendo uma base de dados integrada para um dispositivo médico de electroterapia, sendo a electrosterapia uma modalidade da Medicina Física e Reabilitação. O projecto foi desenvolvido de aco...

  12. Realidad Aumentada en Interiores: posicionamiento del usuario en dispositivos móviles y aplicaciones en rehabilitación y guiado (GuIAR)

    OpenAIRE

    Martínez Ospina, Anaolena

    2013-01-01

    La amplia difusión de los dispositivos móviles en el mercado actual ha puesto al alcance de la mano, altas capacidades de cómputo y diversidad de sensores. Esto ha posibilitado el auge de la Realidad Aumentada, lo cuál busca superponer información al mundo real con el fin de enriquecerlo para un fin determinado. Este trabajo presenta un estado de la cuestión sobre esta área de investigación y se centra específicamente en la Realidad Aumentada en espacios interiores. Uno de los principales pro...

  13. Desarrollo de una aplicación que permita el escaneo de las vulnerabilidades en los dispositivos móviles Android para mitigar los problemas de seguridad

    OpenAIRE

    Villa Yánez, Henry Mauricio

    2016-01-01

    El trabajo de investigación Desarrollo de una aplicación que permita el escaneo de las vulnerabilidades en los dispositivos móviles Android para mitigar los problemas de seguridad realizado en la ciudad de Riobamba, beneficia principalmente a los desarrolladores de software para la realización de una programación segura bajo Android. El presente trabajo de investigación utiliza el método científico porque utiliza varias etapas para obtener un conocimiento válido, lo que ha perm...

  14. Prácticas de control socio-penal dispositivo psi pericial y adolescentes mujeres en el Sistema Penal Juvenil Uruguayo /

    OpenAIRE

    López Gallego, Laura

    2016-01-01

    La presente tesis doctoral "Prácticas de Control Socio-Penal. Dispositivo Psi Pericial y Adolescentes Mujeres en el Sistema Penal Juvenil Uruguayo" se sitúa en una perspectiva analítica que articula postulados de la Psicología Social Crítica y las Epistemologías Feministas, junto con aportes criminológicos provenientes de la Criminología Crítica y la Criminología Feminista. Los itinerarios de investigación producidos en esta tesis doctoral se descomponen en dos proyectos de investigación. Uno...

  15. TELLA: Aplicación educativa en dispositivos móviles para el aprendizaje de matemáticas de niños con necesidades especiales

    OpenAIRE

    ORTA LÓPEZ, JORGE

    2016-01-01

    [ES] TELLA es un proyecto financiado por el gobierno de Noruega con el objetivo de crear una aplicación en dispositivos móviles capaz de ayudar a niños con necesidades especiales en su aprendizaje de matemáticas. Desarrollado principalmente para tabletas, la aplicación se encuentra en estos momentos disponible en los mercados Google Play y AppStore. TELLA es una aplicación que contiene más de 250 pequeños juegos que, con animaciones e interacciones, aprenden matemáticas de forma inconscie...

  16. Desarrollo de un modelo para la recopilación de datos geoespaciales de la infraestructura productiva del gobierno provincial de Chimborazo con dispositivos móviles

    OpenAIRE

    Zarate Piray, Jaime Patricio

    2017-01-01

    1.Introducción. --2.Planteamiento de la Propuesta de Trabajo. --3. Marco Teórico. --4. Metodología. --5. Resultados. --6. Conclusiones y Recomendaciones. El presente trabajo de investigación tiene como objetivo el desarrollo de un modelo para la recopilación de datos geoespaciales de la infraestructura productiva del Gobierno Provincial de Chimborazo usando dispositivos móviles y herramientas open source. El modelo se basa en una adecuación del método de Desarrollo Rápido de Aplicaciones e...

  17. Desarrollo de una aplicación práctica para dispositivos móviles combinando bases de datos y programación en Java

    OpenAIRE

    Zurita Alonso, Efrén

    2015-01-01

    El objetivo principal de este Proyecto Final de Carrera es el desarrollo de una aplicación mediante el lenguaje de programación Java que ofrezca un servicio de videoclub virtual en dispositivos móviles. La aplicación desarrollada ofrece las funcionalidades requeridas para agregar y borrar clientes o películas del videoclub, actualizar las bases de datos de clientes y películas, realizar un alquiler por parte de un cliente ya existente, recomendar películas en base a los gustos del cliente, mo...

  18. Arquitectura de diseño de accesorios electrónicos inalámbricos para dispositivos móviles inteligentes

    OpenAIRE

    Molera Codina, Juan Manuel

    2013-01-01

    El principal objetivo de este Proyecto Fin de Carrera es proponer una arquitectura hardware y software que permita realizar un prototipado rápido y sencillo de accesorios electrónicos para dispositivos móviles inteligentes basados en el sistema operativo Android. Para conseguir este objetivo será necesario llevar a cabo los siguientes sub-objetivos: 1.Buscar y seleccionar los kits de desarrollo necesarios que permitan conseguir una arquitectura para diseñar Gadgets para dispos...

  19. Altjeringa e didgeridoo: dispositivos identitários australianos na espacialidade polifônica de Priscilla, a rainha do deserto, de Stephan Elliott

    OpenAIRE

    Santana, Jorge Alves

    2016-01-01

    Resumo: Priscilla, a rainha do deserto (1994), filme australiano de Stephan Elliott, expressa de modo socioestético um panorama de dispositivos produtores de subjetividades contemporâneas na Austrália. Observaremos, nesse estudo, alguns aspectos da produção de tais subjetividades, nas possíveis mobilidades transversais, dispostas nas relações tensionadas pelas espacialidades - em seus lugares e não-lugares, espaços lisos e estriados (AUGÉ, 1992; 1997; 2006; DELEUZE, 1997) - percorridas pelo t...

  20. La formación profesional inicial universitaria y el análisis multirreferencial de dispositivos destinados a la formación profesional.

    OpenAIRE

    Souto, Marta; Mazza, Diana; Monetti, Elda

    2010-01-01

    El trabajo se propone indagar en los modos de gestión de la formación universitaria de carácter pre-profesional, en tres casos de la investigación “La formación profesional inicial universitaria y el análisis multirreferencial de dispositivos destinados a la formación profesional”, dirigido por Marta Souto. El problema de investigación es ¿cómo se piensa y resuelve la formación profesional inicial (o pre-profesional) en las carreras universitarias? ¿Qué modalidades y caracterís...