Jovanka Broz and fashion: the collection of the first lady

OpenAIRE

Mirjana Menković

2016-01-01

The paper showcases a part of the collection of the first lady of SFRY, Jovanka Broz, captured in photographs taken between 1953 and 1980. The issue of the lack of primary sources is considered – the lack of objects and explicit attitudes of the first lady herself, with the goal of offering a methodological approach through which this deficiency could be overcome. The paper uses the method of chronological tracking of political events, trends in the world of fashion and events in the fashion ...

Incorporating a Sorghum Habitat for Enhancing Lady Beetles (Coleoptera: Coccinellidae in Cotton

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P. G. Tillman

2012-01-01

Full Text Available Lady beetles (Coleoptera: Coccinellidae prey on insect pests in cotton. The objective of this 2 yr on-farm study was to document the impact of a grain sorghum trap crop on the density of Coccinellidae on nearby cotton. Scymnus spp., Coccinella septempunctata (L., Hippodamia convergens Guérin-Méneville, Harmonia axyridis (Pallas, Coleomegilla maculata (De Geer, Cycloneda munda (Say, and Olla v-nigrum (Mulsant were found in sorghum over both years. Lady beetle compositions in sorghum and cotton and in yellow pyramidal traps were similar. For both years, density of lady beetles generally was higher on cotton with sorghum than on control cotton. Our results indicate that sorghum was a source of lady beetles in cotton, and thus incorporation of a sorghum habitat in farmscapes with cotton has great potential to enhance biocontrol of insect pests in cotton.

Regulatory Bodies: Dramatic Creativity, Control and the Commodity of Lady Audley's Secret

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Kate Mattacks

2009-04-01

Full Text Available 'Lady Audley's Secret' resonates with a sense of theatricality grounded in the eponymous heroine's propensity for visual tactics to attract an audience. Repositioning the dramatic exchange between actress and audience within the domestic sphere sensitised the reader to the question of diagnosing morally degenerative artificiality whilst involving the reader in the complicit act of encouraging Lady Audley's performance through consumer demand. This complex relationship between consumerism, theatre and society saw Lady Audley's figure assume an iconic status, but little has been written on the creative interplay between the novel and the theatre itself. Beginning with the way in which aspiring actresses used Lady Audley as a model to display their histrionic variety, I argue that the theatre used her character to engage with the complex connections between drama and commodity culture. Her autophagy in favour of a false identity provided a model for actresses to visualise self-commodification whilst highlighting the tension between the material practices of the theatre and the materiality of commodity culture. The drive for regulation of the theatrical medium finds its locus in the licensing text/published acting edition of William E. Suter's 'Lady Audley's Secret' (1863. Here I move to show how Suter's adaptation functioned as a site where the state regulation of the theatre was explored and contested. These unauthorised images of Lady Audley's containment came to symbolise not only the regulatory processes of licensing and copyright, but also the creative exploitation of a commodity culture critiqued through the dehumanised form of Braddon's original heroine.

Lady Mary Sidney Herbert a Lady Mary Wroth: labutí píseň a imaginativní svět jako součást rodinného odkazu (Lady Mary Sidney Herbert and Lady Mary Wroth: a Swan song and Fictional World as a part of Sidneyan legacy

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Martina Kastnerová

2017-03-01

Full Text Available The study intends to clarify the process of forming of Sidneyan literary cult as a part of (Sidneyʼs family legacy based on the the literary activities of Sidneyʼs sister Lady Mary Sidney Herbert, countess of Pembroke, and his niece Lady Mary Wroth, daughter of his younger brother Robert. Mary Sidney Herbert throughout her literary career sings a swan song of her brother, Mary Wroth creates an imaginative world of free love choice and happy endings and her literary career is based on the well-established cult of Sidneyʼs name.

Dominance of the multicoloured Asian lady beetle Harmonia axyridis in an undisturbed wild meadow ecosystem

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Élise Bélanger

2011-12-01

Full Text Available Fifteen years after its arrival in Quebec (Canada, the multicoloured Asian lady beetle Harmonia axyridis (Pallas 1773 (Coleoptera: Coccinellidae has become one of the dominant coccinellid species in agricultural, forested and urban areas. Several studies conducted in North American agricultural ecosystems show that the arrival of H. axyridis and other exotic coccinellid species was followed by decreases in the populations of native coccinellid species. In this study, the abundances of H. axyridis and other native and exotic species were determined in an undisturbed wild meadow located in a protected area. In 2009 and 2010, mainly Solidago canadensis L. (Asteraceae and Asclepias syriaca L. (Asclepiadaceae infested with aphids were surveyed. A total of 1522 individuals, belonging to seven different species, were recorded. In 2009, on all the plants monitored, H. axyridis was clearly the dominant species (69% of the coccinellid assemblage. In addition, this exotic species constituted 84% of the coccinellid assemblage, including Propylea quatuordecimpunctata (L. and Coccinella septempunctata (L. It is likely the dominance of the eurytopic Asian lady beetle in agricultural, forested, urban and undisturbed open ecosystems, poses a threat to native lady beetles. These results also provide evidence that undisturbed wild meadow ecosystems will not constitute a natural refuge from Harmonia axyridis for native species of lady beetles.

Microscopic study of weathering of white Flemish stone from the monumental Church of Our Lady in Breda, The Netherlands

NARCIS (Netherlands)

Larbi, J.A.; Hees, R.P.J. van; Naldini, S.

2003-01-01

This paper deals with the use of an integrated microscopic method to assist in the investigation of the causes and the extent of decay of the stones and ornaments in the gothic Clurch of Out Lady in Breda, The Netherlands. The purpose of the study was to determine whether conservation measures were

Women Doctors and Lady Nurses: Class, Education, and the Professional Victorian Woman.

Science.gov (United States)

Heggie, Vanessa

2015-01-01

The lives of the first women doctors in Britain have been well studied by historians, as have the many debates about the right of women to train and practice as doctors. Yet the relationship between these women and their most obvious comparators and competitors-the newly professionalized hospital nurses-has not been explored. This article makes use of a wide range of sources to explore the ways in which the first lady doctors created "clear water" between themselves and the nurses with whom they worked and trained. In doing so, it reveals an identity that may seem at odds with some of the clichés of Victorian femininity, namely that of the intelligent and ambitious lady doctor.

Ladies of News

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Milagros Socorro

2009-12-01

Full Text Available This essay looks around the participation of women in the history of Venezuelan Journalism, emphasizing the importance of these “ladies of news” in the development of social communication in the country: since the field practices until the teaching in Journalism and Communication Schools. With a chronicle writing, and detailing the work made by several brave women, Milagros Socorro features this important part of the Venezuelan Journalism.

Diabetes mellitus, hypertension and medial temporal lobe atrophy: the LADIS study

DEFF Research Database (Denmark)

Korf, E S C; van Straaten, E C W; de Leeuw, F-E

2007-01-01

HYPOTHESIS: Based on recent findings on the association between vascular risk factors and hippocampal atrophy, we hypothesized that hypertension and diabetes mellitus (DM) are associated with medial temporal lobe atrophy (MTA) in subjects without disability, independent of the severity of white...... matter hyperintensities. METHODS: In the Leukoaraiosis And DISability in the elderly (LADIS) study, we investigated the relationships between DM, hypertension, blood pressure and MTA in 582 subjects, stratified by white matter hyperintensity severity, using multinomial logistic regression. MTA...... was visually scored for the left and right medial temporal lobe (score 0-4), and meaned. RESULTS: Mean age was 73.5 years (sd 5.1), 54% was female. Of the subjects, 15% had DM, and 70% had a history of hypertension. The likelihood of having MTA score 3 was significantly higher in subjects with DM (OR 2.9; 95...

The Modern First Lady and Public Policy: From Edith Wilson through Hillary Rodham Clinton.

Science.gov (United States)

Black, Allida M.

2001-01-01

Discusses the role in and influence on public policy of twentieth century First Ladies including Edith Roosevelt, Helen Taft, Ellen Wilson, Edith Wilson, Florence Harding, Lou Henry Hoover, Eleanor Roosevelt, Jacqueline Kennedy, Lady Bird Johnson, Rosalynn Carter, Nancy Reagan, Barbara Bush, and Hillary Rodham Clinton. (CMK)

Tarotkorttien historiaa pelikortteina : kohteena Lady Knight -kortti

OpenAIRE

Pylkkö, Ina

2015-01-01

Opinnäytetyö käsittelee tarot-korttien historiaa pelikortteina ja Cary-Yale Visconti -tarotpakan Lady Knight -korttia. Opinnäytetyöhön kuuluu toiminnallinen osuus, jossa toteutettiin uusi versio Lady Knight -kortista yhdistämällä digitaalinen maalaus ja kultaus. Tarot-kortteja on tutkittu taidehistorian sekä viestinnän näkökulmasta vain vähän. Opinnäytetyö rajaa ulkopuolelle ennustukseen ja okkultismiin liittyvät teoriat ja keskittyy näin pelin historiaan. Työssä perehdytään ensin taideh...

Neuropsychological Predictors of Dementia in a Three-Year Follow-Up Period: Data from the LADIS Study

NARCIS (Netherlands)

Madureira, S.; Verdelho, A.; Moleiro, C.; Ferro, J.M.; Erkinjuntti, T.; Jokinen, H.; Pantoni, L.; Fazekas, F.; van der Flier, W.M.; Visser, M.; Waldemar, G.; Wallin, A.; Hennerici, M.; Inzitari, D.

2010-01-01

Background: White matter changes (WMC) are related to cognitive deficits and dementia. Our aim was to determine the extent to which the performance in neuropsychological tests would be able to predict the clinical diagnosis of dementia. Methods: The LADIS (Leukoaraiosis and Disability) is a

The Contested White Lady: A Critique of New Zealand Cultural Heritage Politics

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Lindsay Neill

2012-10-01

Full Text Available This article critiques New Zealand’s cultural heritage politics by positing that vernacular items, like an iconic eatery called the White Lady, does not meet the legislative criteria enabling cultural heritage status. If vernacular artefacts, including ‘kiwiana’, are to be integrated within cultural heritage, then changes within legislation, definitions and participant preconceptions are necessary. This study argues that cultural heritage is dominated by artefacts and historic places; that ‘kiwiana’ and other vernacular items of social history, practice and tradition are relegated. Items of ‘kiwiana’ act as touchstones of identity for New Zealanders. Therefore, their omission distorts the view of New Zealand’s cultural heritage. The application of cultural heritage status to the White Lady is important because of its transcendence of time and social change, its aesthetic, and also because of its present-day hospitality offering.

Response of different populations of seven lady beetle species to lambda-cyhalothrin with record of resistance.

Science.gov (United States)

Rodrigues, Agna R S; Spindola, Aline F; Torres, Jorge B; Siqueira, Herbert A A; Colares, Felipe

2013-10-01

Simultaneous use of biological and chemical controls is a valued and historic goal of integrated pest management, but has rarely been achieved. One explanation for this failure may be the inadequate documentation of field populations of natural enemies for insecticide tolerance or resistance because natural enemies surviving insecticide application do not create problems like resistant pest species. Therefore, this study investigated 31 populations of lady beetles (Coleoptera: Coccinellidae) regarding their susceptibility to lambda-cyhalothrin, a pyrethroid insecticide that is widely used in cotton and other crops to control lepidopteran and coleopteran pests that are not targeted as prey by lady beetles. The study focused on seven coccinellid species common in cotton fields Coleomegilla maculata De Geer, Cycloneda sanguinea (L.), Eriopis connexa Germar, Harmonia axyridis (Pallas), Hippodamia convergens Guérin-Méneville, Olla v-nigrum (Mulsant), and Brumoides foudrasi (Mulsant) and one lady beetle species [Curinus coeruleus Mulsant] from a non-cotton ecosystem for comparisons. Dose-mortality curves were estimated after topical treatment of adult lady beetles with lambda-cyhalothrin. Statistically significant variations in lady beetle susceptibility were observed between species and between populations of a given species. Seven and eighteen populations of lady beetles exhibited greater values of LD50 and LD90, respectively, than the highest recommended field rate of lambda-cyhalothrin (20g a.i./hectare≈0.2g a.i./L) for cotton fields in Brazil. Furthermore, based on LD50 values, 29 out of 30 tested populations of lady beetles exhibited ratios of relative tolerance varying from 2- to 215-fold compared to the toxicity of lambda-cyhalothrin to the boll weevil, Anthonomus grandis Boh. (Coleoptera: Curculionidae). Four populations of E. connexa were 10.5-37.7 times more tolerant than the most susceptible population and thus were considered to be resistant to lambda

Hedgehog pathway activity in the LADY prostate tumor model

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Kasper Susan

2007-03-01

Full Text Available Abstract Background Robust Hedgehog (Hh signaling has been implicated as a common feature of human prostate cancer and an important stimulus of tumor growth. The role of Hh signaling has been studied in several xenograft tumor models, however, the role of Hh in tumor development in a transgenic prostate cancer model has never been examined. Results We analyzed expression of Hh pathway components and conserved Hh target genes along with progenitor cell markers and selected markers of epithelial differentiation during tumor development in the LADY transgenic mouse model. Tumor development was associated with a selective increase in Ihh expression. In contrast Shh expression was decreased. Expression of the Hh target Patched (Ptc was significantly decreased while Gli1 expression was not significantly altered. A survey of other relevant genes revealed significant increases in expression of Notch-1 and Nestin together with decreased expression of HNF3a/FoxA1, NPDC-1 and probasin. Conclusion Our study shows no evidence for a generalized increase in Hh signaling during tumor development in the LADY mouse. It does reveal a selective increase in Ihh expression that is associated with increased expression of progenitor cell markers and decreased expression of terminal differentiation markers. These data suggest that Ihh expression may be a feature of a progenitor cell population that is involved in tumor development.

Aphid secondary symbionts do not affect prey attractiveness to two species of predatory lady beetles.

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Jennifer L Kovacs

Full Text Available Heritable symbionts have been found to mediate interactions between host species and their natural enemies in a variety of organisms. Aphids, their facultative symbionts, and their potential fitness effects have been particularly well-studied. For example, the aphid facultative symbiont Regiella can protect its host from infection from a fungal pathogen, and aphids with Hamiltonella are less likely to be parasitized by parasitic wasps. Recent work has also found there to be negative fitness effects for the larvae of two species of aphidophagous lady beetles that consumed aphids with facultative symbionts. In both species, larvae that consumed aphids with secondary symbionts were significantly less likely to survive to adulthood. In this study we tested whether adult Harmonia axyridis and Hippodamia convergens lady beetles avoided aphids with symbionts in a series of choice experiments. Adults of both lady beetle species were as likely to choose aphids with symbionts as those without, despite the potential negative fitness effects associated with consuming aphids with facultative symbionts. This may suggest that under natural conditions aphid secondary symbionts are not a significant source of selection for predatory lady beetles.

The American Woman Series: Gender and Class in "The Ladies' Home Journal," 1897.

Science.gov (United States)

Kitch, Carolyn

1998-01-01

Contributes to (and draws on) journalism history, mass-culture studies, and women's history in a rhetorical analysis of a series of six full-page illustrations titled "The American Woman" run in 1897 in "The Ladies' Home Journal." Reveals how class and gender issues intersected and underscored the role of the mass media in…

"Letters to a lady": questions of gender and the dissemination of Darwinism in Brazil

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Moema de Rezende Vergara

Full Text Available Recent works on the history of scientific dissemination in Brazil have practically ignored the category of gender in their analysis. Thus, this article is intended to contribute to the content of a study of a specific practice of scientific disclosure of the 1800s, as exemplified by"Letters to a lady" written by Rangel S. Paio and published in the "O Vulgarizador". In this case, the concept of gender makes it possible to understand the tensions between the masculine and feminine appearing in a series of letters meant for purposes of scientific dissemination, in which the author himself anticipated their gender conten, insofar as he directed his attention to a public of 'ladies' in the Second Monarchical reign in Brazil.

The Blue Lady Case and the International Issue of Ship Dismantling - Comment

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Florent Pelsy

2008-09-01

Full Text Available This paper focuses on the decision of the Supreme Court of India to allow the dismantling of the Blue Lady (ex France in Alang. The first part underlines that the Supreme Court of India is prioritising the commercial interest of the dismantling companies over the social and environmental concerns of the workers and the communities living in Alang. It argues that such decision goes against its 2003 judgement on ship-dismantling. It then demonstrates that the Supreme Court of India is distorting the concept of sustainable development. The second part analyses the Blue Lady case from an international perspective since most of the ships that are dismantled in India come from developed countries. It provides an overview of the Basel Convention on ship dismantling issues and a study of the Clemenceau case before the French Conseil d'Etat. It then concludes that a better control of end-of-life ships in OECD countries and a new international convention on ship-dismantling would be necessary in order to prevent environmental and social disasters in Alang.

Mapping Femininity as Self-reflection Strategy in Lady Mary Wortley Montagu’s Travel Letters

OpenAIRE

Amelia Precup

2017-01-01

The present paper participates in the discussion about the differences between masculine and feminine modes of travel in terms of interests, perception, and representation, by exploring the Letters of the Right Honourable Lady M--y W--y M--e Written during Her Travels in Europe, Asia and Africa, by Lady Mary Wortley Montagu. As a traveller, Lady Mary engaged in the contemplation of cultural landscapes: she attempted to understand the social logic of the communities she met and to assess the c...

The Lady Spaceman: Children's Perceptions of Sex-Stereotyped Occupations.

Science.gov (United States)

Rosenthal, Doreen A.; Chapman, Diane C.

1982-01-01

Children from single-sex and coeducational schools were asked to name male and female occupants of traditionally sex-linked roles. Children's use of linguistic markers (e.g. lady doctor) was associated with labeling of female occupants of traditionally male roles and male occupants of traditionally female roles, indicating that language reflects…

Pursuing public and professional perception of nuclear energy with the Smithsonian Lady Godiva replica and demonstration/display

International Nuclear Information System (INIS)

Grundl, J.A.

1987-01-01

The following topics were addressed by the speaker at the Fast Burst Reactor Workshop banquet: (1) Lady Godiva and the perception of nuclear energy, (2) the question of public and professional perception of nuclear energy, (3) notions of public perception among Lady Godiva replicators, and (4) the nuclear fission chain: complete embodiment of nuclear energy

Iron lady, reflexiones sobre la imagen y el liderazgo. Iron lady, reflections about image and leadership

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María Arnal Canudo

2012-04-01

Full Text Available A través de diversas teorías sobre el liderazgo así como la influencia del cine en el legado visual y biográfico de algunas personalidades relevantes, este artículo analiza el liderazgo de Margaret Thatcher mostrado en la película Iron Lady, sobrenombre con el que se la conoce. El largometraje presenta la figura de la que fuera primera ministra de Gran Bretaña a través de los recuerdos de su protagonista, los factores y circunstancias personales que influyeron en su estilo de gobernar y liderazgo, su personalidad y su faceta en el entorno familiar.Through some theories about leadership as well as the influence of the cinema in the visual and biographical legacy of some excellent personalities, this article analyzes the Margaret Thatcher’s leadership in the film Iron Lady, nickname with which she is known. The film shows the ex Prime Minister of Great Britain through hers personal memories, factors and circumstances that influenced in her style to govern and her leadership, its personality and its facet in the familiar surroundings.

Impact of white matter hyperintensities scoring method on correlations with clinical data: the LADIS study

DEFF Research Database (Denmark)

van Straaten, EC; Fazekas, F; Rostrup, Egill

2006-01-01

BACKGROUND AND PURPOSE: White matter hyperintensities (WMH) are associated with decline in cognition, gait, mood, and urinary continence. Associations may depend on the method used for measuring WMH. We investigated the ability of different WMH scoring methods to detect differences in WMH load...... between groups with and without symptoms. METHODS: We used data of 618 independently living elderly with WMH collected in the Leukoaraiosis And DISability (LADIS) study. Subjects with and without symptoms of depression, gait disturbances, urinary incontinence, and memory decline were compared with respect...... to WMH load measured qualitatively using 3 widely used visual rating scales (Fazekas, Scheltens, and Age-Related White Matter Changes scales) and quantitatively with a semiautomated volumetric technique and an automatic lesion count. Statistical significance between groups was assessed with the chi2...

Effect of Chemical Treatment on Physical, Mechanical and Thermal Properties of Ladies Finger Natural Fiber

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S. I. Hossain

2013-01-01

Full Text Available In present research, natural fiber obtained from ladies finger plant was chemically treated separately using alkali (2% NaOH, chromium sulfate (4% , and chromium sulfate and sodium bicarbonate (4% . Both raw and chemically treated fibers were subsequently characterized using mechanical (tensile, structural (Fourier transform infrared spectroscopy and scanning electron microscopy, and thermal (thermogravimetric analysis. Fourier analysis showed the presence of (−OH group in the ladies plant fiber. Scanning electron micrographs revealed rougher surface in case of alkali treated fiber, while thin coating layer was formed on the fiber surface during other two treatments. Tensile test on ladies finger single fiber was carried out by varying span length. The tensile strength and Young's modulus values were found to be increased after chemical treatment. For both raw and chemically treated fibers, Young's modulus increased and tensile strength decreased with increase in span length. Thermogravimetric analysis indicated the same level of thermal stability for both raw and treated ladies finger fibers.

Physical activity in the elderly is associated with improved executive function and processing speed: the LADIS Study.

Science.gov (United States)

Frederiksen, Kristian Steen; Verdelho, Ana; Madureira, Sofia; Bäzner, Hansjörg; O'Brien, John T; Fazekas, Franz; Scheltens, Philip; Schmidt, Reinhold; Wallin, Anders; Wahlund, Lars-Olof; Erkinjunttii, Timo; Poggesi, Anna; Pantoni, Leonardo; Inzitari, Domenico; Waldemar, Gunhild

2015-07-01

Physical activity reduces the risk of cognitive decline but may affect cognitive domains differently. We examined whether physical activity modifies processing speed, executive function and memory in a population of non-dementia elderly subjects with age-related white matter changes (ARWMC). Data from the Leukoaraiosis And DISability (LADIS) study, a multicenter, European prospective cohort study aimed at examining the role of ARWMC in transition to disability, was used. Subjects in the LADIS study were clinically assessed yearly for 3 years including MRI at baseline and 3-year follow-up. Physical activity was assessed at baseline, and cognitive compound scores at baseline and 3-year assessment were used. Two-hundred-eighty-two subjects (age, y (mean (SD)): 73.1 (± 5.1); gender (f/m): 164/118); MMSE (mean (SD)): 28.3 (± 1.7)) who had not progressed to MCI or dementia, were included. Multiple variable linear regression analysis with baseline MMSE, education, gender, age, stroke, diabetes and ARWMC rating as covariates revealed that physical activity was associated with better scores at baseline and 3-year follow-up for executive function (baseline: β: 0.39, 95% CI: 0.13-0.90, p = 0.008; follow-up: β: 0.24, 95% CI: 0.10-0.38, p = 0.001) and processing speed (baseline: β: 0.48, 95% CI: 0.14-0.89, p = 0.005; follow-up: β: 0.15, 95% CI: 0.02-0.29, p = 0.02) but not memory. When including baseline cognitive score as a covariate in the analysis of 3-year follow-up scores, executive function remained significant (β: 0.11, 95% CI: 0-0.22, p = 0.04). Our findings confirm previous findings of a positive effect of physical activity on cognitive functions in elderly subjects, and further extends these by showing that the association is also present in patients with ARWMC. Copyright © 2014 John Wiley & Sons, Ltd.

Mapping Femininity as Self-reflection Strategy in Lady Mary Wortley Montagu’s Travel Letters

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Amelia Precup

2017-07-01

Full Text Available The present paper participates in the discussion about the differences between masculine and feminine modes of travel in terms of interests, perception, and representation, by exploring the Letters of the Right Honourable Lady M--y W--y M--e Written during Her Travels in Europe, Asia and Africa, by Lady Mary Wortley Montagu. As a traveller, Lady Mary engaged in the contemplation of cultural landscapes: she attempted to understand the social logic of the communities she met and to assess the cultural distance between the English society and the local customs of the countries she visited. Within this large social and cultural framework, the focus of her keen spirit of observation is represented, in many of her letters, by gender dynamics and the status of women, thus allowing a feminine configuration of the map of continental Europe and the Ottoman Empire and a comparative understanding of femininity and expected feminine behaviour. Therefore, the contention of this paper is that, in Lady Mary’s letters, the female-traveller’s gaze ends in meditation and self-contemplation, and functions as a means of comparing and reassessing female identity.

História noturna de Nossa Senhora do Risca-Faca Dark history of our Lady of the Slash-Knife

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John C. Dawsey

2009-04-01

Full Text Available No Jardim das Flores, sobre as cinzas do antigo bairro do Risca-Faca, vivem as filhas - ou netas e bisnetas - de escravas e "índias laçadas no mato". Muitas delas também se consideram filhas de Nossa Senhora. A justaposição das linhagens maternas pode suscitar um efeito de montagem. Nas inervações corporais de Nossas Senhoras não lampejam, também, os gestos de índias e escravas? Nos subterrâneos dos símbolos se encontram indícios de "histórias noturnas" de Nossa Senhora. Sobre esse terreno, o estudo de processos de povoamento em Piracicaba, no interior paulista, requer uma espécie de arqueologia: um duplo deslocamento, de um bandeirante povoador a Nossa Senhora, e de Nossa Senhora às índias e escravas "laçadas no mato". Nesses fundos, o gesto de uma mulher "boia-fria" que "fez picadinho de um homem" agita as sombras de uma nação.In the Garden of Flowers, over the ashes of the old Slash-Knife District, live the daughters - or granddaughters and great-granddaughters - of slaves and native South-American women "lassoed in the woods". Many consider themselves also to be the daughters of Our Lady. The juxtaposition of maternal lineages may produce a montage-like effect. Do gestures of Indians and slaves flash in the bodily innervations of Our Lady? Signs of "dark histories" of Our Lady are found in subterranean regions of symbols. On this terrain, the study of historical patterns of settlement in Piracicaba, a city of the interior of São Paulo, may require a certain type of archaeology, involving a double dislocation, from bandeirante explorers to Our Lady, and from Our Lady to Indian and slave women "lassoed in the woods". In these substrata the gesture of a boia-fria woman who "cut a man into pieces" stirs up the shadows of a nation.

Cleaning lady saves the day

CERN Multimedia

2009-01-01

At lunch time on Wednesday 21 January a guest at the CERN hostel put her food in the microwave oven and switched it on. "Within seconds I smelt plastic. I looked into the oven and saw flames. I switched it off, took my food out. But the flames continued and so I ran for the door." In the corridor she ran into Jane Kiranga, a cleaning lady working for the company ISS. Without hesitation Jane picked up a portable fire extinguisher, returned to the kitchen and stopped the fire. The Fire Brigade arrived a few minutes later and only needed to ventilate the kitchen. "Jane was just in time, because the flames had not left the oven yet. Her model behaviour deserves recognition," said the team leader on duty for the CERN Fire Brigade. A few days later Jane received a gift voucher from the Prevention and Training section of the Safety Commission (photo).

The Tragedy of a Patriarchal Angel: On Lady Macbeth’s Submission to Patriarchy in Macbeth

Institute of Scientific and Technical Information of China (English)

黄琳

2015-01-01

William Shakespeare(1564-1616),as Ben Jonson assured us,is "not of an age but for all time".Macbeth,one of William Shakespeare’s most important plays,is much favored by critics for its representation of the female character Lady Macbeth who is usually regarded as the "fiend-like Queen" or a super witch by Goethe.Nevertheless,other critics like Christina Leon Alfar asserted in her article "Blood will have blood: Power,Performance,and the Trouble with Gender" believe that Lady Macbeth represented gender stereotyping.Therefore,in this essay,she is represented as a perfect wife,"The Angel in the House",and the "Other" in men’s world______________。

The Tragedy of a Patriarchal Angel：On Lady Macbeth’s Submission to Patriarchy in Macbeth

Institute of Scientific and Technical Information of China (English)

黄琳

2015-01-01

William Shakespeare (1564-1616),as Ben Jonson assured us,is“not of an age but for all time”.Macbeth,one of William Shakespeare’s most important plays,is much favored by critics for its representation of the female character Lady Macbeth who is usually regarded as the“fiend-like Queen” or a super witch by Goethe.Nevertheless,other critics like Christina Leon Alfar asserted in her article“Blood will have blood: Power,Performance,and the Trouble with Gender” believe that Lady Macbeth represented gender stereotyping.Therefore,in this essay,she is represented as a perfect wife,“The Angel in the House”,and the“Other” in men’s world ______________.

Changes in the landsnail fauna of Lady Alice Island, northeastern New Zealand

International Nuclear Information System (INIS)

Brook, F.J.

1999-01-01

A small coastal dunefield on Lady Alice Island off northern New Zealand incorporates a stratigraphic record of the historic period and much if not all of the period of prehistoric Maori occupation of the island. Fossil landsnail faunas from the dunefield are closely comparable with those from present-day dune shrubland habitats and differ from contiguous hillslope forest and shrubland faunas. Three of the landsnail species are no longer extant on Lady Alice Island. Two are large species (Amborhytida tarangensis, Placostylus hongii) that are inferred to have become extinct following the introduction of kiore (Rattus exulans) to the island. Failure to find any snail shells with breakages characteristic of rat predation suggests that kiore may not have established on the island until the early 19th century. The other smaller species of landsnail (Phrixgnathus paralaomiformis) probably became extinct in the late 19th or early 20th century as a result of habitat disturbance from fires and cattle. (author). 56 refs., 5 figs., 4 tabs

Restoring the rare Kentucky lady's slipper orchid to the Kisatchie National Forest

Science.gov (United States)

James P. Barnett; Kevin Allen; David Moore

2012-01-01

The Kentucky lady’s slipper (Cypripedium kentuckiense C.F. Reed [Orchidaceae]) is a spectacular orchid native to the southeastern US. Although its range includes much of the Southeast, it is rare due to loss of appropriate edaphic and climatic habitats. Efforts to restore this species to the Kisatchie National Forest in Louisiana were initiated by a high school student...

Aspekte van die outeursfunksie in Antjie Krog se Lady Anne (1989)

OpenAIRE

M. Crous

2002-01-01

Aspects of the author function in Antjie Krog’s Lady Anne (1989) The purpose of this essay is to investigate the Foucauldian notion of the so-called “author function” in Antjie Krog’s seventh volume of poetry, viz. Lady Anne (1989). It is an attempt to show how the notion of the death of the author (Barthes) links up with this theorisation of Foucault. Furthermore, it is also an attempt to indicate the characteristic features of the so-called “author function” in the late eighties in Afr...

Ibsen's mermaid in China: adapting The lady from the sea for the traditional Yue theatre

Directory of Open Access Journals (Sweden)

Terry Siu-han Yip

2015-02-01

Full Text Available Ibsen has created Ellida Wangel in The Lady from the Sea as a “mermaid” stranded on land, feeling trapped in her marriage with Dr Wangel and suffocated by her restrictive gender roles as wife and step-mother. The play focuses on Ellida the dying mermaid’s process of individuation as she struggles to seek happiness, freedom and self-fulfilment in life. Through Ellida’s entangled relationship with the Stranger and her husband, Ibsen has created a living “mermaid”, who enables him to explore gender relations, individual freedom and choice, as well as the liberation of the self.             However, when The Lady from the Sea was transposed from Norway to China and adapted for the traditional Chinese theatre, the Chinese Yue theatre in this case, Ellida had undergone drastic changes in order to suit the traditional Yue theatregoers’ expectations and taste, as well as to fit the socio-cultural norm of traditional Yue opera.             Instead of examining those technical alterations such as rearrangement of scenes (Ye, 2011, 20, the use of symbols (Wu, 2011, 80, the setting (Wu, 2011, 78, or theatrical performance and devices (Qing Yun, 2010, 32 adopted in the Chinese operatic adaptation of The Lady from the Sea, this article focuses on the cultural re-presentation of Ellida and the re-constitution of her character, the purpose of which is to make her plausible as a Chinese woman on the traditional Yue stage. A close study of the cultural transformation of Ellida and her re-orientation on the traditional Yue stage adaptation will enable the reader to better understand the Chinese cultural emphasis on didacticism, Confucian morality and propriety in traditional drama and theatre, as well as the difficulties involved in transporting Ibsen’s mermaid to the Chinese traditional Yue stage.

Jovanka Broz and fashion: the collection of the first lady

Directory of Open Access Journals (Sweden)

Mirjana Menković

2016-03-01

Full Text Available The paper showcases a part of the collection of the first lady of SFRY, Jovanka Broz, captured in photographs taken between 1953 and 1980. The issue of the lack of primary sources is considered – the lack of objects and explicit attitudes of the first lady herself, with the goal of offering a methodological approach through which this deficiency could be overcome. The paper uses the method of chronological tracking of political events, trends in the world of fashion and events in the fashion industry, as well as statements by participants and witnesses of certain events. Through comparison of these three aspects, we indirectly arrive at a view of the relationship of Jovanka Broz to clothing and fashion, as well as to a view of the key influences of the first lady’s collection on the fashion choices of the political elite and the fashion industry of SFR Yugoslavia. Jovanka Broz’s public appearance changed over time, from a careful selection of photographs without personal comment, through the recording of statements on formal occasions, to giving interviews to chosen journalists on specific topics – these changes are noted in the paper. It can be concluded that the fashion choices of Jovanka Broz were, first and foremost, aligned with the protocols demanded by international diplomacy, as well as that Jovanka Broz herself approached this demands with the utmost diligence, as well as personal attitude.

LADY GAGA: UNINDO MODA, MÚSICA POP E ARTE

Directory of Open Access Journals (Sweden)

Letícia Guedes de Paula

2017-03-01

Full Text Available O trabalho em questão insere-se no contexto de uma pesquisa mais ampla a respeito da relação entre Moda e Arte. Analisam-se aspectos da obra da artista pop Lady Gaga, que desenvolve seus trabalhos multifacetados sob uma perspectiva segundo a qual Moda e Música são dimensões da Arte Pop. A proposta de Lady Gaga é influenciada por Andy Warhol e transparece não apenas em suas produções artísticas, como também em suas declarações à imprensa, objeto de análise deste estudo. Gaga busca o status de Arte para seus trabalhos, independentemente do aspecto comercial que estes possam apresentar. Sua proposta, que pode ser resumida na afirmação “o que é feito com Arte permanece”, pode ser aplicada indistintamente a qualquer dos aspectos de sua obra, Música e Moda incluídas.

A cultural diversity seen in Croatian family medicine: a lady from Janjevo.

Science.gov (United States)

Pavlov, Renata

2014-12-01

The role of cultural diversities in doctor's everyday work is going more and more important in globalised world, therefore it draws lots of attention in literature. Cultural differences that exist between people, such as language, dress and traditions, are usually distinguished from the term cultural diversity which is mainly understood as having different cultures respect each other's differences. The great effort is made to educate culturally competent practitioners, nurses or doctors. The presented case of lady from Janjevo was a good role model for work with all patients with culturally different background coming to family practice. This lady example could also help to other colleagues to learn from experience on systematic way.

[Student Magazine of the ESL Classes of the International Ladies' Garment Workers' Union (ILGWU).

Science.gov (United States)

Alvarez, Manuel, Ed.; Zetino, Alfredo, Ed.

This student magazine created by the English-as-a-Second-Language (ESL) classes of the International Ladies' Garment Workers' Union (ILGWU) is a collection of personal opinions, reports, and creative writing with illustrations. Each item was written as a voluntary collaboration, homework, or classwork. Items include poems, letters, accounts of…

Pattern of breast cancer experience at lady reading hospital, Peshawar

International Nuclear Information System (INIS)

Naeem, M.; Khan, N.; Samad, A.

2008-01-01

Breast Cancer is the commonest malignancy of females all over the world and second leading cause of death due to cancer among females. The aim of this Descriptive study was to see the various features of breast cancer in order to know the pattern of disease in the recent time. The study was conducted from Jan. 2007 to Dec. 2007 in Surgical C Unit, Postgraduate Medical Institute, Lady Reading Hospital, Peshawar, Pakistan. Study included all patients presenting to and admitted in Surgical C Unit LRH, with carcinoma of breast during the above mentioned period. Name, age, sex, other relevant data, history and examination findings and results of histopathology and other investigations were recorded. Total of 46 patients was included in the study, out of which there were 46 female and 1 male patients. Most common age group was 40-49 years with 14 patients, followed by 50-59 years with 12 patients. Most common type of carcinoma was infiltrating ductal carcinoma with no specific features with 38 patients. Other types included 2 infiltrating ductal carcinomas of papillary type, 1 mucinous type and 1 medullary type; 3 invasive lobular carcinomas, and 1 mixed lobular and ductal carcinoma. The disease was left sided in 24 cases, right sided in 20 cases while it was bilateral in 2 cases. Upper outer quadrant of the breast was most commonly involved (n=26). There were 2 cases of stage I, 16 stage II, 20 stage III and 08 cases of stage IV disease. There were 2 cases of grade I, 16 grade II, and 28 cases of grade III. Carcinoma breast is still a common problem presenting at a young to middle age group with invasive ductal carcinoma being the commonest variant with a high grade and a late stage of presentation due to lack of screening and awareness programs. (author)

Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort

DEFF Research Database (Denmark)

Ryberg, C; Rostrup, E; Paulson, O B

2011-01-01

) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive......The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS...

Corpus callosum atrophy as a predictor of age-related cognitive and motor impairment: a 3-year follow-up of the LADIS study cohort

DEFF Research Database (Denmark)

Ryberg, C; Rostrup, E; Paulson, O B

2011-01-01

The aim of this 3-year follow-up study was to investigate whether corpus callosum (CC) atrophy may predict future motor and cognitive impairment in an elderly population. On baseline MRI from 563 subjects with age-related white matter changes (ARWMC) from the Leukoaraiosis And DISability (LADIS......) study, the CC was segmented and subdivided into five anterior-posterior regions (CC1-CC5). Associations between the CC areas and decline in motor performance and cognitive functions over a 3-year period were analyzed. CC atrophy at baseline was significantly associated with impaired cognitive...

Facebook marketing communications plan for Ladies Gym

OpenAIRE

Orelma, Lilja

2016-01-01

Ladies Gym is a gym located in Vantaa, Finland. Until now, the company’s marketing actions have been limited to occasional e-mail newsletters, posters on the walls of the gym, and a newspaper advertisement once a year. The outcome of this thesis is a Facebook marketing communications plan that will be implemented by the company. Marketing communications and B-2-C relationship management are covered in the theoretical framework. Facebook as a marketing communications tool is covered in mor...

Iron lady, reflexiones sobre la imagen y el liderazgo. Iron lady, reflections about image and leadership

OpenAIRE

María Arnal Canudo

2012-01-01

A través de diversas teorías sobre el liderazgo así como la influencia del cine en el legado visual y biográfico de algunas personalidades relevantes, este artículo analiza el liderazgo de Margaret Thatcher mostrado en la película Iron Lady, sobrenombre con el que se la conoce. El largometraje presenta la figura de la que fuera primera ministra de Gran Bretaña a través de los recuerdos de su protagonista, los factores y circunstancias personales que influyeron en su estilo de gobernar y lider...

Ladies of Charity: Forgotten Pioneers of Social Assistance in Mexico, 1863-1910

Directory of Open Access Journals (Sweden)

Silvia Marina Arrom

2007-10-01

Full Text Available The Asociación de Señoras de la Caridad (Association of Ladies of Charity was one of the largest Mexican women's organizations during the Porfiriato. It mobilized thousands of lay women volun­teers throughout the country, helping hundreds of thousands of poor people, as they strengthened their Catholic faith and values. Besides visiting those in need both in their homes and in public hospitals and jails, these women created and managed their own schools, hospitals, nursing homes, and other welfare institutions, thus contributing to Mexican systems of education, health, and social assistance. Without challenging the social standards of their time, the ladies of Charity carried out novel practices for Mexican women, and expanded the traditional limits of the feminine world.

THE FIRST LADY INSTITUTE IN THE EXPERIENCE OF THE EASTERN SLAVIA

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Inna Kalita

2016-10-01

Full Text Available The article analyzes the First Lady Institute experience in modern eastern Slavia. The examples of gender representation from the late Soviet era and the highest level gender “defeat” in some post-Soviet states are compared. The First Lady’s presentation and self-presentation are seen as an indicator of democratic changes in the state. The accumulated experience reflects the real condition of gender issue unpopularity among some leaders of Eastern Slavonic states, so it proves the immaturity of governmental democratic systems in Russia, Belarus and Ukraine. The analyzed paradigm also reflects the decline of the family institution prestige.

Self-perceived memory complaints predict progression to Alzheimer disease. The LADIS study

DEFF Research Database (Denmark)

Verdelho, Ana; Madureira, Sofia; Moleiro, Carla

2011-01-01

of follow-up, 90 patients were demented (vascular dementia, 54; Alzheimer's disease (AD) and AD with vascular component, 34; frontotemporal dementia, 2). Using Cox regression analysis, we found that self perceived memory complaints were a strong predictor of AD and AD with vascular component during...

Achalasia of the Cardia in a 21 Year old Pregnant Lady: A Case ...

African Journals Online (AJOL)

Achalasia of the cardia is a motor disorder of the lower oesophagus of unknown aetiology. It is characterized by persistent dysphagia in 82 – 100% of patients. We describe a rare case of dysphagia due to Achalasia cardia in a pregnant lady in her third trimester. Tanzania Medical Journal Vol. 23 (2) 2008: pp. 31-32.

The contribution of technology in business growth: The case of Greek ladies

OpenAIRE

Vassilakopoulou, Angelina

2013-01-01

The overall image of the use of digital technology by Greek women is not that encouraging. In information communication technology companies in the Greek market, there are only few ladies in high management mainly related to HR and marketing functions. The statistics on internet use show that although its penetration to the population is growing rapidly, there is a steady 10% gap between men (55%) and women (45%) use. It also becomes obvious, in relevant market surveys, that the internet is c...

CASE REPORT Thirty years old lady with nephrotic syndrome: a ...

African Journals Online (AJOL)

CASE REPORT. Thirty years old lady with nephrotic syndrome: a case of biopsy proven lupus nephritis in Tanzania. FRANCIS FREDRICK1,2*, PASCHAL J. RUGGAJO2,3,GYAVIIRA MAKANGA3, CHARLES K. SHIJA3, MIKAEL. AMDEMARIAM3, BELSON RUGWIZAGONGA4 and JAMES N. KITINYA4. 1Department of ...

Collar of Lady's Wear in Qing Dynasty

Institute of Scientific and Technical Information of China (English)

LI Xiao-jun

2007-01-01

The research is started with a query that whether the width of collar in Qing Dynasty Is too small. The paper bases on the statistics which come from the collection of the Costume Museum of Donghua University. compares the results with the natlonal standard specification, then analyzes the structure and shape of collars in Qing Dynasty, and tells the relationship between collar and the garment. Furthermore, the paper discusses the function of lady's collar in Qing Dynasty and gives a suggestion that collar being an Indicator to distinguish women's wear from children's wear.

The main altarpiece of Our Lady of the Elms church in Torre de Juan Abad, Spain: technical study and condition state

Directory of Open Access Journals (Sweden)

Rosario Llamas

2013-01-01

Full Text Available The altarpiece of the church of Our Lady of the Elms, in Campo de Montiel, attributed to Francisco Cano, is a unique masterpiece that represents the essence of the Mannerism or Late Renaissance in the region. Its technical study is one of the objectives of this article that seeks to explain the constructive aspects and identify the materials (wood species, pigments and binders and the techniques used. Simultaneously, we have characterized its current state of preservation, describing in detail the problems identified, both structurally and in terms of the polychromy. We have tried to revalue an important work that got to survive the events of the Spanish Civil War. Generally speaking, it is unpublished information that has been collected and presented here.

Sir John and Lady Rita Cornforth: a distinguished chemical partnership.

Science.gov (United States)

Purchase, Rupert; Hanson, James R

2015-01-01

This review describes the life of Sir John Cornforth AC CBE FRS, who was awarded the Nobel Prize for Chemistry in 1975. It covers his early life in Australia, his work in Oxford, the National Institute for Medical Research, the Milstead Laboratory of Chemical Enzymology and the University of Sussex, together with the contributions made by his wife, Lady Rita Cornforth.

Adsorptive removal of congo red and sunset yellow dyes from water systems by lady finger stem

International Nuclear Information System (INIS)

Abbas, A.; Murtaza, S.; Ayub, R.; Rehman, R.; Zahid, A.

2012-01-01

Summary: In this research work two anionic dyes, i.e. Congo Red and Sunset Yellow were removed successfully from aqueous media by Lady Finger stem in batch mode. Operational conditions optimization showed that agitation speed and particle size did not affect much in adsorption of these dyes; but contact time, pH, adsorbent dose and temperature of system effects the adsorption rate. Optimized conditions of adsorption for Congo Red dye were: 40 minute contact time, 8.0 pH, 0.5 g adsorbent dose, 40-60 microns mesh sized particles, 150 rpm agitation speed and 50 degree C temperature. Whereas for Sunset Yellow optimized conditions were: 30 minute contact time, 2.0 pH, 2.5 g adsorbent dose, 20-40 microns mesh sized particles, 50 rpm agitation speed and 30 degree C temperature. Suitability of equilibrium data was modulated with Langmuir, Freundlich and Temkin models and found that both physisorption and chemisorption processes play important role in adsorption of these dyes by Lady Finger stem. The results demonstrated that Lady Finger stem can be efficiently employed on larger scale wastewater treatment. (author)

Dan Goldin chats with First Lady Hillary Clinton

Science.gov (United States)

1999-01-01

At the Apollo/Saturn V Center, NASA Administrator Daniel Goldin (right) chats with First Lady Hillary Rodham Clinton and others while waiting for the launch of STS-93. Much attention has been generated over STS-93 due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X-ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes. Liftoff of Space Shuttle Columbia is scheduled for 12:36 a.m. EDT July 20.

The urban short story cycle before Joyce: James Stephens’ Here are Ladies

OpenAIRE

Brouckmans, Debbie

2013-01-01

Published ten years after George Moore’s The Untilled Field (1903) and one year before James Joyce’s Dubliners (1914), James Stephens’ Here are Ladies (1913) consists of short stories, poems and monologues. The work is not often discussed, presumably because it is rather difficult to define. It is usually classified as a collection of short stories, but this neglects the poems and monologues and fails to do justice to the thematic and formal links between the texts. Therefore, I would like to...

Deep frontal and periventricular age related white matter changes but not basal ganglia and infratentorial hyperintensities are associated with falls: cross sectional results from the LADIS study

DEFF Research Database (Denmark)

Blahak, C; Baezner, H; Pantoni, L

2009-01-01

non-disabled individuals with reported falls was analysed, using the cross sectional data of the Leukoaraiosis and Disability (LADIS) study. Detailed anatomical distributions of ARWMC assessed by MRI studies were analysed with respect to falls and balance performance. RESULTS: The severity of global...... ARWMC was significantly associated with a history of falls in the year prior to study inclusion (22.2% in the mild, 31.6% in the moderate and 37.3% in the severe ARWMC group according to the Fazekas scale; p = 0.002). Analysing the anatomical distribution of ARWMC, using the semiquantitative Scheltens...

Extrapulmonary tuberculosis in lady reading hospital peshawar, NWFP, pakistan: survey of biopsy results

International Nuclear Information System (INIS)

Rehman, A.U.; Kamal, A.

2008-01-01

Tuberculosis is a disease of poor countries. In the recent years, there has been an increase in the occurrence of extra-pulmonary tuberculosis (EPTB) world over. As very little data is available regarding the situation of EPTB in NWFP, this study was conducted to asses its frequency in various organ systems of the body and to evaluate the role of demographic factors like sex and age in its causation. A total of 525 cases of EPTB diagnosed histopathologically in the Department of Pathology, Lady Reading Hospital Peshawar in the years 2002-2005 were included in the study. Age, sex and sites of biopsies were recorded. High female preponderance was noted with a M:F ratio of 1:2. Mean age was 35 years and 70% of the patients were in the age group 15-45 years. Lymph nodes were the most common site of EPTB, involved in 66.4% of the cases. EPTB has high rates in females in their reproductive age. Tuberculous lymphadenitis is the most common form of EPTB. High occurrence of EPTB in female population needs immediate attention of tuberculosis control programs. (author)

Gender blending a queer performativita ve videoklipech Lady Gaga

OpenAIRE

Sekyrová, Karolína

2014-01-01

This bachelor thesis examines how queer performativity and gender blending are shown in the music video clips of Lady Gaga. The thesis attemp to find and analyse through the means of the semiotic analysis and explain their meaning. The thesis is based on theoretical gender definition and on two constructivism concepts: Doing gender by West and Zimermann and gender performativity by Judith Butler. The thesis employs the queer concept as the reconstruction of sexual minorities but also as an an...

Arcabas’s paintings in the Shrine of Our Lady of La Salette

Directory of Open Access Journals (Sweden)

Piotr Szweda

2016-12-01

Full Text Available Acting under the nickname Arcabas, Jean-Marie Pirot is a contemporary French religious painter, totally unknown in Poland. Arcabas’s artistic output is enormous, albeit difficult to catalogue. Today his works can be admired in many churches in France, in other locations across Europe, as well as in North and South America, or even in distant Japan. Our article presents a synthesis of the artistic path of Arcabas as a versatile painter who likes to influence human senses by colours while looking for harmony and beauty as God’s humble follower. In his works he transfers biblical scenes to canvas, transforming them into visual art. Moreover, we analysed six Arcabas’s paintings exhibited in the cradle of the congregation of Missionaries of Our Lady of La Salette, i.e. in the shrine of Our Lady of La Salette in France: The Wedding at Cana, Mouring at Calvary, Christ Pantocrator, The Symbols of Five Evangelists, Crowned Madonna with Child Jesus, La Salette – the Encounter. The artist’s smooth transitions from the literal to the abstract, and even combining both in a single work cause Arcabas’s works to be greeted with enthusiasm on the one hand, but criticized on the other. Jean-Marie Pirot’s art is far from clear or easy to absorb; it is rather challenging and ambiguous. It holds a mystery that intrigues, invites and encourages us to look deeper. It contains strong links to traditional Christian art, both eastern and western. The painter is not satisfied with merely becoming part of the long tradition and being inspired by themes from the repertoire of the past. He is not a slave to traditional figurative art, although his works do contain references to this tradition; instead, he demonstrates his creativity, always coming up with something new. In addition, Arcabas’s output demonstrates exceptional freedom in intertwining the sacred with the profane, sometimes suggesting that the very division should be rejected. His works, including

Judy Collins and First Lady Hillary Clinton await the launch of STS-93

Science.gov (United States)

1999-01-01

Singer Judy Collins (left) and First Lady Hillary Rodham Clinton await the launch of Space Shuttle mission STS-93 in the Apollo/Saturn V Facility. Liftoff is scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. Judy Collins has honored the commander with a song, 'Beyond the Sky,' which was commissioned by NASA through the NASA Art Program.

Do Old Ladies Make World History?: Student Perceptions of Elder Female Agency

Science.gov (United States)

Woodbum, Stephen M.

2006-01-01

In this article, the author shares the views of his undergraduate students regarding elder female agency and their answers to the question: "Do old ladies make world history?" Because his undergraduate students mostly view the past in terms of the Great Man theory of history, which holds that those who make history are necessarily great,…

Phytochemical analysis, antioxidant, antistress, and nootropic activities of aqueous and methanolic seed extracts of ladies finger (Abelmoschus esculentus L.) in mice.

Science.gov (United States)

Doreddula, Sathish Kumar; Bonam, Srinivasa Reddy; Gaddam, Durga Prasad; Desu, Brahma Srinivasa Rao; Ramarao, Nadendla; Pandy, Vijayapandi

2014-01-01

Abelmoschus esculentus L. (ladies finger, okra) is a well-known tropical vegetable, widely planted from Africa to Asia and from South Europe to America. In the present study, we investigated the in vitro antioxidant capacity and in vivo protective effect of the aqueous and methanolic seed extracts of Abelmoschus esculentus against scopolamine-induced cognitive impairment using passive avoidance task and acute restraining stress-induced behavioural and biochemical changes using elevated plus maze (EPM) and forced swimming test (FST) in mice. Our results demonstrated that the pretreatment of mice with aqueous and methanolic seed extracts of Abelmoschus esculentus (200 mg/kg, p.o.) for seven days significantly (P nootropic activities which promisingly support the medicinal values of ladies finger as a vegetable.

Childhood Heart Disease - A partnership model of integrated care

OpenAIRE

Williams, Holly; Brooke, Mark

2018-01-01

HeartKids is a national charity supporting infants, children, young people and adults living with or impacted by congenital / childhood heart disease. For over 20 years HeartKids has worked in partnership with Lady Cilento Children's Hospital to deliver services and support to families.HeartKids supports families in hosptial and in the commuity with a suite of support programs lead by both health profesisonals and volunteers.  Critical to our model of care is a partnership with Lady Cilento C...

First Ladies' Symposium on Early Childhood in Egypt (Cairo, Egypt, May 21, 2001).

Science.gov (United States)

O'Gara, Chloe

This document is comprised of the papers presented at the First Ladies' Symposium on Early Childhood in Egypt in May 2001. Participating in the symposium were representatives from the World Bank, the Amsterdam Institute for International Development, the Children's Project, and the Academy for Educational Development. The symposium opened with an…

Lima bean – lady beetle interactions: hooked trichomes affect survival of Stethorus punctillum larvae

Science.gov (United States)

We tested the hypothesis that Lima bean Phaseolus lunatus L. (Henderson cultivar) trichome density affects the survival of the acariphagous lady beetle Stethorus punctillum Weise. When isolated throughout larval development, 10% or less of S. punctillum larvae reared on two-spotted spider mite Tetr...

The art of transformation: art, marriage, and freedom in The lady from the sea

Directory of Open Access Journals (Sweden)

Toril Moi

2009-12-01

Full Text Available The play, The Lady from the Sea, sets out to provide an answer to the question: namely, what it takes for a relationship to become a marriage. In order to follow Ibsen’s analysis of this question, however, we also need to notice that the play can be read as Ibsen’s rebuff to romantic tales of female sacrifice. The play also intertwines the story of Ellida’s achievement of freedom with an investigation of art, theatre, and music, in which the main question is how painting, sculpture, and theatre can express what some critics have called the “inner mind”. --- Original in English.

Ruth Flockart and Dr Wood: A Crucial Relationship in the Development of Melbourne Methodist Ladies' College Music Program

Science.gov (United States)

Jenkins, Louise

2011-01-01

This paper explores the notion that particular working relationships within school music programs can have a significant affect on the program's development and progress. To explore this notion the research focussed on the working relationship of a music teacher at Melbourne Methodist Ladies' College (MLC), Ruth Flockart (1891-1985) and the…

Judy Collins shares a laugh with First Lady Hillary Clinton

Science.gov (United States)

1999-01-01

Singer Judy Collins (left) shares a laugh with First Lady Hillary Rodham Clinton in the Apollo/Saturn V Facility. Both women are at KSC to view the launch of Space Shuttle mission STS-93 scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. Judy Collins has honored the commander with a song, 'Beyond the Sky,' which was commissioned by NASA through the NASA Art Program.

Over-the-counter self-medication leading to intracranial hypertension in a young lady.

Science.gov (United States)

Ramana Reddy, A M; Prashanth, L K; Sharat Kumar, G G; Chandana, G; Jadav, Rakesh

2014-10-01

Intracranial hypertension (idiopathic-IIH and secondary) is a potentially treatable condition. Although various factors such as female gender and obesity, certain drugs have been implicated as risk factors for IIH, there remains a lack of clarity in the exact causal-effect relationship. In India, self-medication by obtaining drugs over the counter due to lack of adequate drug regulation and ignorance of the public is a very common practice with a potential for severe adverse effects. We present a case of a young lady who has developed intracranial hypertension possibly due to self-medication with steroids and cyproheptadine, obtained over the counter.

Small is challenging; distal femur fracture management in an elderly lady with achondroplastic dwarfism.

Science.gov (United States)

Murphy, Colin G; Chrea, Bopha; Molloy, Alan P; Nicholson, Paul

2013-03-20

Achondroplasia is an autosomal dominant dwarfing condition that represents the most common form of skeletal dysplasia. The disease is caused by a mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) found at the p16.3 locus on chromosome 4 which results in severe inhibition of subchondral bone growth. Anatomic variations, including articular and periarticular deformities classically seen with this condition, amplify the complexity of fracture fixation. Blood volume loss, age-related bone fragility, component selection and positioning pose serious orthopaedic challenges. Concomitant cardiovascular, respiratory and neurological comorbidities pose additional high-risk perioperative considerations. Despite an estimated prevalence of 1:25 000 in the general population, there is little literature concerning the operative and postoperative treatment challenges faced by orthopaedic surgeons dealing with fracture management on a patient with this condition. We present a case of an intercondylar femoral fracture in an elderly achondroplastic lady successfully treated with percutaneous screw fixation.

A Clinico-Pathological Study on Benign Breast Diseases

Science.gov (United States)

Sangma, Mima B. Maychet; Panda, Kishori; Dasiah, Simon

2013-01-01

Background: To study the patterns of clinically benign breast disease in females and to co-relate them with the pathological findings. Methods: One hundred females who attended the Surgery Outpatients Department in Indira Gandhi Medical College and Research Institute, Pondicherry, with various forms of benign breast diseases during the period from October 2011 to September 2012, were studied. Early diagnoses by doing a triple assessment like a clinical examination, FNAC or a core needle biopsy and imaging methods like ultrasonography or mammography, were made within 72 hrs from the first consultation. The clinical diagnoses were compared with the cytological or histological findings wherever possible and their accuracies were evaluated. Results: Out of the 100 female patients who were studied, 87 patients who presented with breast lumps and fibroadenoma, accounted for 48% of the cases, which was the highest number of patients. Fibrocystic changes and breast abscesses came next with 18% and 12% cases respectively. We detected 3 cases of proliferative disease with atypia and one case with florid hyperplasia, which had high and low risk factors respectively, for developing invasive carcinoma. The oldest lady of the group who was clinically diagnosed to have benign disease, was detected to have invasive ductal carcinoma. They were treated in our hospital and were advised follow up. Conclusion: Benign breast diseases are common in female patients and fibroadenoma is the commonest of them all. Triple assessment provided a quick diagnosis and it alleviated unnecessary anxiety from the patients about breast cancer. The clinical diagnosis of a breast lump, as confirmed by cytology and histology, was accurate in 91.95 % of the cases. PMID:23634406

Our Lady of the Rosary in the Marian Sanctuary: Brotherhoods and Black Devotions in Salvador and the Recôncavo Baiano (Eighteenth Century

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Tânia Maria PINTO DE SANTANA

2016-06-01

Full Text Available Organized by Frei Agostinho de Santa Maria and published in 1722, the Marian Sanctuary and History of the Miracles image of Our Lady consist the registrations of marian invocations worshiped in Portuguese territory, made by clergymen from differents parishes in the xviii century. The ninth volume deal witch the invocations found in Bahia. In this article we mean to use this text as a study sourse for the history religious belief, as well as in the study of the Catholic religiosity history among the black people in the reconcavo baiano. The reconcavo baiano was one of the most important region of the sugar cane production in the American Portuguesa in that period where concentrated an expressive population of black people that was used in the slave labor in that production. Our analysis which has as a main objective of study Our Lady of Rosario worship in the brotherhoods and the black people’s devotions in that region. Seeking to understand at first the motivation for such worship, experienced in the context of the slavery. Subsequently we will concentrate our analysis in the aspects linked to its growth and development, such as celebrations for their Patroness, and the use of images in moments of celebrations. From here it’s necessary to comprehend how the place of the black, as a slave or a free man, marked the relations established and the differents moments of celebrations.

Astronaut Parazynski greets First Lady Hillary Clinton and Chelsea Clinton

Science.gov (United States)

1999-01-01

First Lady Hillary Rodham Clinton (right) and her daughter, Chelsea, are greeted by NASA Astronaut Scott E. Parazynski (left) upon their arrival at the Skid Strip at Cape Canaveral Air Station to view the launch of Space Shuttle mission STS-93. Liftoff is scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X-ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes.

Variant dialogue structures in the story by A.P. Chekhov "Lady with dog"

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Natalya V. Izotova

2016-09-01

Full Text Available The article analyzes the different ways of constructing dialogue communication of the characters in A.P. Chekhov’s story «Lady with the Dog», appearing in the written text space. Variant dialogue structures are means of creating both character’s plane, and the plane of the reader, as dialogues are formed only with the participation of the reader’s consciousness of the perceiver. Formation of dialogical communication takes place with the help of different ways to transfer other speech, clotting the real dialogue, incompleteness of canonical dialogical structure that makes it possible to expand the world of the character by including the reader’s perception.

How the Other Half Lives: Under the Arch with Lady Henry Somerset

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Paisana Joanne

2017-10-01

Full Text Available The reforming work of Isabella Caroline Somerset (Lady Henry Somerset 1851-1921 is largely overlooked today. Dedicated to women’s causes at home and abroad and to temperance in particular, having first-hand knowledge of the privileged and the underprivileged, this determined, multi-talented and opinionated woman uncharacteristically wrote a fictional novel, Under the Arch (1906. In the novel, London aristocrats are portrayed rubbing shoulders with slum dwellers, but there is little real connection. The problems that the social policies introduced by the Liberals from 1906-1914 would address are nevertheless highlighted. It can be no coincidence that Somerset was well acquainted with many of these politicians. The themes of relieving the poor, Christian doctrine, marriage, women’s suffrage and imperialism are addressed, although Somerset’s focus is simply on “doing good” and loving one’s neighbour

Factitious prey and artificial diets for predatory lady beetles: current situation, obstacles, and approaches for improvement

Science.gov (United States)

Predatory lady beetles (Coleoptera: Coccinellidae) are important natural enemies of many pests in crop ecosystems throughout the world. Although several species are currently mass-reared and sold by biocontrol companies, there is an urgent need to reduce rearing costs. Cost effective mass rearing of...

A System for Harvesting Eggs from the Pink-Spotted Lady Beetle

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Margaret L. Allen

2012-01-01

Full Text Available We describe a system for harvesting eggs from a predatory insect, the pink-spotted lady beetle, Coleomegilla maculata De Geer (Coleoptera: Coccinellidae. Adult beetles placed in square, transparent containers that included oviposition substrates hanging from the top of the cage deposited eggs on the materials provided. We harvested eggs from these substrates in quantities sufficient for either destructive sampling or synchronous development of larvae. We evaluated effects of crowding inside cages; effects of a chemical attractant on oviposition behavior; egg cannibalism. Females preferred a textured surface rather than a smooth, waxy one for laying eggs. Crowding inhibited oviposition of beetles. Presence of a chemical attractant (methyl salicylate did not significantly improve oviposition. This paper describes an inexpensive system for harvesting eggs from C. maculata. Refinement of this system should improve oviposition and reduce cannibalism.

The Uncontrollable Mnemonic Fragments within Consciousness Reflecting Ophelia’s and Lady Macbeth’s Disturbed Minds

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Ekmekçioğlu Neslihan

2015-12-01

Full Text Available Memory plays an important role in most of Shakespeare’s plays. Shakespeare delves into the dark realms of human consciousness to reflect the disturbed minds and gnawing consciences of his characters with a profound psychological insight into the human psyche. Time, memory, madness and death seem to be the basic issues dealt with in his canon. My paper will address the uncontrollable mnemonic fragments within the human consciousness which reflect past traumas, fears and disturbances and will examine the cases of Ophelia and Lady Macbeth from a feminist reading of women.

The first lady phenomenon:Elites, states, and the contradictory politics of women’s empowerment in the neoliberal arab world

OpenAIRE

Sukarieh, Mayssoun

2015-01-01

Drawing on analysis of different sources-media analysis, policy documents, interviews, and participant observation-this article analyzes the representation of Queen Rania of Jordan and the First Lady of Syria, Asma al-Assad, and their work in civil society. An analysis of Rania and Assad helps illustrate the ways in which gender roles and representations, in the Arab and Muslim world as elsewhere, are always multiple and contradictory, varying across lines of social class and intimately conne...

First lady meets AIDS patients in Thailand.

Science.gov (United States)

1996-12-09

First Lady Hillary Rodham Clinton, during her tour of Thailand: 1) joined a panel discussion at New Life Center, a missionary shelter and acquired immunodeficiency syndrome (AIDS) hospice that houses and educates 151 girls from remote hill tribes who were rescued from being, or from becoming, brothel prostitutes or "restaurant hostesses"; 2) inspected a U.S. supported program in Chiang Rai province that provides scholarships, vocational training, and jobs to 1200 girls as income alternatives to their sale; and 3) toured a school that extends the education of girls beyond the mandatory age of 12, the age at which many are sold to Bangkok brothel middlemen. There are 500,000-700,000 prostitutes in Thailand; many die of AIDS. Girls can be sold for $1000 and send money home later; instead of poverty, the family has a new home, a motorcycle, and status. Mrs. Clinton emphasized the lifetime benefit available to a family when a girl is educated.

First Lady Hillary Clinton waits for launch at VIP viewing site

Science.gov (United States)

1999-01-01

Among those gathered at the VIP viewing site for the launch of STS-93 are First Lady Hillary Rodham Clinton (center) and Donna Shalala, secretary , Department of Health and Human Services (far right). Also present is Chelsea Clinton. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X-ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes. Liftoff of Space Shuttle Columbia is scheduled for 12:36 a.m. EDT July 20.

Atlantic mackerel and Horse mackerel egg survey 2016: Dutch participation on board FV Atlantic Lady: May

NARCIS (Netherlands)

Damme, van C.J.G.

2016-01-01

From 10 till 25 May 2016 IMARES carried out a mackerel and horse mackerel egg survey on board the FV Atlantic Lady. This survey was part of the international mackerel and horse mackerel egg survey coordinated by ICES. The Redersvereniging voor de Zeevisserij (RVZ) asked IMARES to carry out this

First Lady Hillary Clinton is greeted by NASA Administrator Goldin

Science.gov (United States)

1999-01-01

First Lady Hillary Rodham Clinton and her daughter, Chelsea, are greeted by NASA Administrator Daniel S. Goldin upon their arrival at the Skid Strip at Cape Canaveral Air Station. Next to Gold are (from left) Deputy Director for Business Operations Jim Jennings and Mrs. Goldin. Mrs. Clinton and Chelsea are here to view the launch of Space Shuttle mission STS-93, scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five- day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X- ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes.

Dementia and the biopolitics of the biopic: from Iris to The iron lady.

Science.gov (United States)

Wearing, Sadie

2013-05-01

This article considers the question of embodiment through a comparative analysis of two 'biopics', Iris (2001) and The Iron Lady (2011), which both feature eponymous characters that have, or had, dementia. Embodiment draws our attention to the representation of the body in the films themselves, and to the socially significant 'feelings' or affects that circulate within and are reproduced around them. Shame, disgust and aversion are socially devastating affects conventionally associated with stigmatised bodies including those of the cognitively impaired but attention to the 'feeling tone' (Ngai, 2005) in these films demonstrates that a more varied range of affects and embodied social knowledge is produced. Embodiment is thus a starting point to explore what is at stake in these films both in their authorisation of particular versions of public lives and for their significance for the cultural politics of representation in the context of explorations of personhood and dementia.

Jurassic animals and algae in the flooring of Our Lady of Sorrows Church in Poznań

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Antczak Mateusz

2015-12-01

Full Text Available The flooring of Our Lady of Sorrows Church in Poznań is made of Jurassic rocks from the Świętokrzyskie Mountains (also known as Holy Cross Mountains and contain abundant marine invertebrate fossils: sponges, bivalves, brachiopods, various families of cephalopods, etc. Some of them can be identified to the genus level. The fossils make it possible to describe the environment and ecosystem of the Jurassic sea and biostratigraphy of the sediment. There are also some significant inorganic structures, which suggest post-diagenetic tectonic movements.

The poetic rite of rebirth in Sylvia Plath's “Lady Lazarus"

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Sandra Novkinic

2014-12-01

Full Text Available The aim of this paper is to demonstrate the inviolability of „female creativity” in the works of Sylvia Plath through the symbolism of death and rebirth. „Lady Lazarus” reflects Plath’s recognition that the struggle between death and rebirth must direct every aspect of poetic structure. The woman in the poem is at the same time a victim and tormentor. She is a female Lazarus who died because of great suffering that the poet equates with the suffering of the Jews who were tortured during World War II. She is a victim of male cruelty, but also a new woman who rises from the flames. Using the myth of the resurrection of the Phoenix, Sylvia Plath shows a woman who stands up against all the men who restrain her. The allusions in the poem to the biblical, historical, political and personal take the reader into the center of a personality (of a woman.

Condições de atmosfera controlada para a maçã ?Pink Lady?

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Brackmann Auri

2005-01-01

Full Text Available O objetivo do presente trabalho foi avaliar o efeito de diferentes temperaturas e pressões parciais de O2 e CO2 sobre a manutenção da qualidade da maçã (Malus domestica Borkh. cultivar Pink Lady durante o armazenamento em atmosfera controlada. Os tratamentos avaliados foram 1,5kPa de O2 + 1,0kPa de CO2 na temperatura de -0,5degreesC, e 1,5kPa de O2 + 1,0kPa de CO2; 1,5kPa de O2 + 2,0kPa de CO2; 1,0kPa de O2 + 1,0kPa de CO2; 1,0kPa de O2 + <0,5kPa de CO2; armazenamento refrigerado (20,8kPa de O2 + <0,5kPa de CO2 na temperatura de +0,5degreesC. As avaliações foram realizadas após nove meses de armazenamento, seguidos de sete dias de exposição dos frutos a 20degreesC. Os frutos mantidos em atmosfera controlada apresentaram menor ocorrência de podridões, maior firmeza de polpa e maior teor de sólidos solúveis totais, em comparação com os frutos conservados em armazenamento refrigerado. As melhores condições de atmosfera controlada para conservação da qualidade da maçã ?Pink Lady? foram 1,5kPa de O2 + 1,0kPa de CO2 na temperatura de -0,5degreesC, e 1,5kPa de O2 + 1,0kPa de CO2; 1,5kPa de O2 + 2,0kPa de CO2 na temperatura de +0,5degreesC, já as pressões parciais 1,0kPa de O2 + 1,0kPa de CO2 e 1,0kPa de O2 + <0,5kPa de CO2 apresentaram maiores valores de podridão e degenerescência senescente, respectivamente. A atmosfera controlada, com exceção da atmosfera refrigerada, mantém conservada a qualidade da maçã ?Pink Lady?.

Mariological paintings in the Chapel of Our Lady's Tomb in the Kalwaria Zebrzydowska compound. From studies on the reception of graphics in Polish 17th century painting

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Janina Dzik

2008-12-01

Full Text Available The Chapel of Our Lady's Tomb in Brody, complete with valuable interior furnishing, in terms of history and territory belongs to the architectural landscape concept of the Marian- and Passion-themed compound in Kalwaria Zebrzydowska. In the fields of the late-Renaissance choir parapet and the galleries of the chapel there are a series of paintings showing hitherto unspecified Marian themes. The items have never been referred to in literature on Kalwaria or mentioned in guidebooks or maintenance records. The article analyses, in a broad context, the symbolism of 37 Marian scenes presenting Mary and symbolic objects (e.g. a heart, a building, a garden.

First Lady Hillary Clinton returns to KSC for second launch attempt

Science.gov (United States)

1999-01-01

Seated in the Banana Creek viewing site, First Lady Hillary Rodham Clinton appears attentive to the conversation of a fellow spectator. Mrs. Clinton and others are gathered to watch the second launch attempt of STS-93. Moments before the first scheduled launch, July 20, STS-93 was scrubbed at the T-7 second mark in the countdown due to an indication of a high concentration of hydrogen in an aft engine compartment. The reading proved to be a false alarm. The launch was rescheduled for July 22 at 12:28 a.m. Much attention has been generated over STS-93 due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe.

Replacement of natural stone in conservation of historic buildings, Evaluation of replacement of natural stone at the church of Our Lady in Breda

NARCIS (Netherlands)

Quist, W.J.

2009-01-01

In this paper the decision process and the choice for specific types of natural stone for conservation purposes are investigated. Two successive 20th century conservation campaigns at the church of Our Lady in Breda are analyzed. It was specifically investigated in how far the architects involved

Astronauts Stefanyshyn-Piper, Lindsey and Currie greet First Lady Hillary Clinton at the Skid Strip

Science.gov (United States)

1999-01-01

First Lady Hillary Rodham Clinton is greeted by Astronauts (from left) Heidemarie M. Stefanyshyn-Piper, Steven W. Lindsey, and Nancy Jane Currie upon Mrs. Clinton's arrival at the Skid Strip at Cape Canaveral Air Station. She and her daughter, Chelsea (far right) are here to view the launch of Space Shuttle mission STS- 93, scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X-ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes.

Depressive symptoms predict cognitive decline and dementia in older people independently of cerebral white matter changes: the LADIS study.

Science.gov (United States)

Verdelho, Ana; Madureira, Sofia; Moleiro, Carla; Ferro, José M; O'Brien, John T; Poggesi, Anna; Pantoni, Leonardo; Fazekas, Franz; Scheltens, Philip; Waldemar, Gunhild; Wallin, Anders; Erkinjuntti, Timo; Inzitari, Domenico

2013-11-01

Depressive symptoms (DS) have been associated with increased risk of cognitive decline. Our aim was to evaluate the longitudinal influence of DS on cognition in independent older people, accounting for the severity of white matter changes (WMC). The LADIS (Leukoaraiosis And DISability in the elderly) prospective study evaluated the impact of WMC on the transition of independent older subjects into disability. Subjects were evaluated annually over a 3 year period with a comprehensive clinical and neuropsychological evaluation. Previous episodes of depression and current DS were assessed during each interview. Severity of DS was assessed using the self-rated 15 item Geriatric Depression Scale. A neuropsychological battery and clinical criteria for cognitive impairments were applied in all clinical visits, and cognitive compound measures were made based on neuropsychological results. MRI was performed at baseline and at year 3. 639 subjects were included (74.1 ± 5 years old, 55% women, 9.6 ± 3.8 years of schooling). Dementia was diagnosed in 90 patients and cognitive impairment not dementia in 147 patients at the last clinical evaluation. DS were an independent predictor of cognitive impairment (dementia and not dementia) during follow-up, independent of the effect of the severity of WMC, medial temporal lobe atrophy, age, education or global cognitive function at baseline. DS are associated with an increase risk of cognitive decline, independent of the effect of WMC, probably due to an additive or synergistic effect. In this context, DS probably represent a subtle ongoing organic dysfunction.

Naturalizing Alterity: Edward Maturin’s Bianca: A Tale of Erin and Italy and Lady Morgan's Italy

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Donatella Abbate Badin

2011-08-01

Full Text Available In the nineteenth century the image of Italy appealed also to Irish Romantic writers. But the way in which they naturalized the Italian alterity is quite ambivalent. On the one hand they filtered their images of the southern country through their relationship with England and thus ended up mirroring stereotypes common to the English-speaking world, and on the other hand they established a special, personal relationship with it shaped by their ideological and cultural differences from the British. This essay tackles the representations of Italy in two texts, namely Edward Maturin’s Bianca: A Tale of Erin and Italy, published in 1852, and in the earlier Italy (1821 by Lady Morgan. Both these works show that at that time there was a certain awareness, in Ireland, of the special historical and political conditions of Italy and of possible similarities with Ireland. Italy, oppressed by foreign domination yet aspiring to freedom, became a yardstick for gauging issues of subjugation, injustice, and national identity and invited sympathy from the citizens of a colonized country. Therefore, Italy was perceived as a mirror in which to reflect the Irish identity torn by aspirations which were hard to confess publicly or even to oneself. Keywords: Maturin, Lady Morgan, alterity, Italy, Irish Romanticism

Interdiscursividade e metadiscursividade no videoclipe Applause, de Lady Gaga

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Lúcio Flávio Gondim da Silva

2015-08-01

Full Text Available Nesta pesquisa, fazemos, com base no arcabouço conceitual da Análise do Discurso, na perspectiva de Maingueneuau (2005, uma análise do clipe Applause (2013, da cantora norte-americana Lady Gaga. Identificamos as relações interdiscursivas e metadiscursivas presentes na obra e analisamos de que modo elas ocorrem. No decorrer do trabalho, foi possível observar que há, no clipe, uma forte presença da metadiscursividade, revelada desde o título da canção até os elementos construídos voltados a este fim. Quanto à interdiscursividade, ela surge em grande número e interliga o discurso literomusical ao qual o clipe pertence aos discursos de grandes correntes estéticas e movimentos de arte, bem como de outras linguagens artísticas, como o cinema, a moda e o teatro.

Concurrent primary hyperparathyroidism and pheochromocytoma in a Chinese lady with neurofibromatosis type 1

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Cheuk-Lik Wong

2018-04-01

Full Text Available We report a case of elderly Chinese lady with neurofibromatosis type-1 presenting with longstanding palpitation, paroxysmal hypertension and osteoporosis. Biochemical testing showed mild hypercalcaemia with non-suppressed parathyroid hormone level suggestive of primary hyperparathyroidism, and mildly elevated urinary fractionated normetanephrine and plasma-free normetanephrine pointing to a catecholamine-secreting pheochromocytoma/paraganglioma. Further scintigraphic investigation revealed evidence of a solitary parathyroid adenoma causing primary hyperparathyroidism and a left pheochromocytoma. Resection of the parathyroid adenoma and pheochromocytoma resulted in normalization of biochemical abnormalities and hypertension. The rare concurrence of primary hyperparathyroidism and pheochromocytoma in neurofibromatosis type-1 is discussed.

"The Lady in Pink: Dress and the Enigma of Gendered Space in Marcel Proust's Fiction"

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Eva Maria Stadler

2005-06-01

Full Text Available A study of the role of clothing as central to issues of characterization, description and historical reference in Marcel Proust's A la recherche du temps perdu. Focus on Odette de Crécy, one of the central characters in the novel, a courtesan who becomes the wife of Charles Swann but who first captivates the narrator's imagination when, as a child, he briefly sees her as a "Lady in Pink." Odette's role as a fashionable woman, as one of the best-dressed women in Parisian society, gives unity to her character. The description of her clothing, however, not only provides the occasion for an accurate recreation of contemporary dress codes. The links between clothing and a woman's body are explicitly explored in creating the character of Odette. Her femininity is defined specifically in terms of surfaces and objects and her personality seems to assume its reality from costume. Dress not only encloses her lovely appearance; it gives substance to her person and order to her life. Through the agency of dress this ordinary, even vulgar woman rises above her condition and enters a world of passion and poetry.

First Lady Hillary Clinton returns to KSC for second launch attempt

Science.gov (United States)

1999-01-01

Entering the Banana Creek viewing site, First Lady Hillary Rodham Clinton is joined by NASA Administrator Daniel Goldin (right), and in the background, Deputy Director of Business Operations Jim Jennings (far left) and Director of Installation Operations Marv Jones (right, behind Goldin). Mrs. Clinton and others are at the site to watch the second launch attempt of STS-93. Moments before the first scheduled launch, July 20, STS-93 was scrubbed at the T-7 second mark in the countdown due to an indication of a high concentration of hydrogen in an aft engine compartment. The reading proved to be a false alarm. The launch was rescheduled for July 22 at 12:28 a.m. Much attention has been generated over STS-93 due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe.

The Microsoft® Crabby Office Lady Tells It Like It Is Secrets to Surviving Office Life

CERN Document Server

Stahl, Annik

2009-01-01

We all have to work for a living-so why not make that time work for you? Whether you're in a cubicle or corner office, the Crabby Office Lady shows you how to be more productive on the job so that you can really enjoy your time off the job. Humorous but practical, the lovable know-it-all reveals her secrets in this easy-to-read survival guide based on her popular column. You'll get her no-nonsense lessons to succeeding at work, as well as tips and tricks for working with Microsoft Office programs to help simplify your life. She'll give you the straight scoop-so pay attention! Crabby says, "L

First Lady Hillary Clinton gets ready to speak to group at VIP viewing site

Science.gov (United States)

1999-01-01

In the VIP Lounge, Apollo/Saturn V Center, First Lady Hillary Rodham Clinton gets ready to speak to the group gathered there before the launch of STS-93. At right is NASA Administrator Daniel Goldin. Liftoff of Space Shuttle Columbia is scheduled for 12:36 a.m. EDT July 20. Much attention has been generated over the launch due to Commander Eileen M. Collins, the first woman to serve as commander of a Shuttle mission. The primary payload of the five-day mission is the Chandra X-ray Observatory, which will allow scientists from around the world to study some of the most distant, powerful and dynamic objects in the universe. The new telescope is 20 to 50 times more sensitive than any previous X- ray telescope and is expected to unlock the secrets of supernovae, quasars and black holes.

On a fast numerical tool for nuclear accidental dynamic phenomenology and application to the real time simulation of Lady Godiva

International Nuclear Information System (INIS)

Bindel, Laurent; Gamess, Andre; Jasserand, Frederic; Laporte, Sebastien

2003-01-01

This paper present a modern numerical method, implemented in a TUI-code named MacDSP, for solving any set of differential equations and in particular phenomenological accidental dynamic calculations. The speed efficiency of such an approach, thanks to the use of the hybrid-level power offered by C++ and an ad-hoc design, make it possible to construct the first kid of a family of real time simulator employing the video games technology DirectX TM : Lady Godiva Real Time Simulator. (author)

Rare small intestinal volvulus from entrapment in hepato-diaphragmatic adhesions in a 45-year-old lady.

Science.gov (United States)

Olaoye, Iyiade Olatunde; Adesina, Micheal Dapo

2016-12-20

Small intestinal volvulus is rare in adults and rarely caused by string adhesions between the liver and the diaphragm. Similar adhesions were described in Fitz-Hugh-Curtis syndrome. We report a 45-year-old lady with small intestinal volvulus from entrapment of a loop in string adhesions between the liver and the diaphragm. Her plain radiographs showed a significant shadow of the trapped loop. Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author 2016.

Defining interdisciplinarity and indentifying Research directions in Jani Christou’s Strychnine lady

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Maria Yerosimou

2014-09-01

Full Text Available Jani Christou was a major Greek composer, whose unusual, yet promising career was brought to an end after his untimely death in 1970 at the age of 44. His challenging and speculative output has intrigued generation of young music scholars; however, J. Christou’s work remains imperfectly and only patchily known and understood, especially outside Greece. This is partly because of the interdisciplinary nature of his late works which reduces the possibility of potential researchers who will academically establish J. Christou’s distinguished output. The aim of the present paper is to present and analyse parts of Strychnine Lady, a work composed in 1967 in order to propose research directions in an effort to confirm J. Christou’s posthumous reputation.

MP3s, rebundled debt, and performative economics: deferral, derivatives, and digital commodity fetishism in Lady Gaga’s spectacle of excess

NARCIS (Netherlands)

Kustritz, A.

2012-01-01

Lady Gaga’s rise to fame in the wake of the global financial crisis highlights the contradictions of late late capitalism in both the financial sector and the music industry. Both Gaga and second level economic units like derivatives rely on deferral, parody, and an ever-widening gap between the

The Avenging Females: A Comparative Analysis of Kill Bill Vol.1-2, Death Proof and Sympathy for Lady Vengeance

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Basak Göksel Demiray

2012-04-01

Full Text Available This paper provides a comparative analysis of Quentin Tarantino’s Kill Bill Vol.1-2 (2003, 2004, Death Proof (2007 and Park Chan Wook’s Sympathy for Lady Vengeance (Chinjeolhan Geumjassi, 2005. The primary objectives of this study are: (1 to reveal the gender-biases inherent to the fundamental discursive structures of the foregoing films; (2 to compare and contrast the films through an analysis of the ‘gaze(s’ and possible ‘pleasures’,  which are inherent in their narratives, in relation to Laura Mulvey’s and Carol Clover’s approaches; and (3 to distinguish Kill Bill Vol.1-2 from the foregoing two and the ‘avenging female’ clichés of the other horror/violence movies in the context of the replaced positionings of its protagonist and antagonist inherent in its distinct narrative style.

Atlantic mackerel and Horse mackerel egg survey 2016: Dutch participation on board FV Atlantic Lady: May

OpenAIRE

Damme, van, C.J.G.

2016-01-01

From 10 till 25 May 2016 IMARES carried out a mackerel and horse mackerel egg survey on board the FV Atlantic Lady. This survey was part of the international mackerel and horse mackerel egg survey coordinated by ICES. The Redersvereniging voor de Zeevisserij (RVZ) asked IMARES to carry out this survey. Numbers of mackerel eggs in the samples were low, lower compared to previous surveys. Most mackerel eggs were found along the 200m depth contour of the continental slope. Most of the adult mack...

“THE TALE OF THE MIRACULOUS ICON OF OUR LADY OF KAZAN” IN THE LIGHT OF OLD RUSSIAN LITERARY TRADITION

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Vladimir M. Kirillin

2017-03-01

Full Text Available “The Tale of the Miraculous Image of Our Lady of Kazan” is related to other Old Russian tales with the motif of apparition or discovery of the icon of Our Lady. Reading this tale in comparison with the tales of Kolochskaya, Tikhvin, Okovetskaya, and Vydropusskaya icons, I will focus on the structure of its plot motifs that organize the tale’s narrative. The essay reveals a combination of traditional and novel features in the construction of the text and the specificity of the story. The latter was determined by some general trends in the development of Russian literature at the end of the 16 th century as well as by the social circumstances in the newly added Kazan State and by the official position of the Kazan Metropolitan Hermogenes, a presumed author of the tale. A comparative reading reveals typicality and conventionality as regards the plot, the structure, and the language of the tale about the Kazan icon, despite the presence of new motifs and elements of authorial self- reflection. The author of the tale rigorously followed official ideological and aesthetic line as well as existing literary standards and was guided by the mainstream clerical, political, and spiritual ideas that did not favor descriptive exaggerations inspired by imagination, religious exaltation, and mysticism. There is a stark contrast between the conventional tale by Anonymous-Hermogenes and legends about Kolochskaya, Okovetskay, and (to some extent Vydropusskaya icons of the Holy Virgin that represent narratives dramatically and stylistically close to the folk speech. Such reading gives grounds to certain conclusions about the peculiarities of the historical development of Russian literature in Moscow Rus’ of the second half of the 16 th century. The official line of its development was primarily aimed at the conservation and formalization of creative work.

A new species of myrmecophilous lady beetle in the genus Diomus (Coleoptera: Coccinellidae: Diomini) from Chiapas, Mexico that feeds on green coffee scale, Coccus viridis (Green) (Hemiptera: Coccidae)

Science.gov (United States)

A new species of myrmecophilous lady beetle in the genus Diomus (Coleoptera: Coccinellidae: Diomini) is described from a coffee agroecosystem in Chiapas, Mexico. The new species was found preying on the green coffee scale pest, Coccus viridis (Green), tended primarily by Azteca sericeasur Longino an...

Re-Innovating. Technological research contribution in the recovery of Our Lady of Mercy Church in Baranzate

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Anna Mangiarotti

2011-04-01

Full Text Available The recovery project of Our Lady of Mercy Church in Baranzate, by Angelo Mangiarotti and Bruno Morassutti, with Aldo Favini for structures, built in 1956, and now in charge by Giulio Barazzetta, Anna Mangiarotti, Ingrid Paoletti, Tito Neri for structures and Giancarlo Chiesa for hvac, has requested a high technological effort in order to identify the technical options in order to ‘re-innovate’ on this building. The aim is to increase performances and internal comfort, while maintaining the original concept of the church. The deteriorated envelope will be changed with a façade envelope in steel dry assembled and a triple glazed unit high performance and with face fritted surfaced in order to reproduce the original architectural effects. Thanks to hvac, performances are radically improved.

Lady Astor's Campaign for Nursery Schools in Britain, 1930-1939: Attempting to Valorize Cultural Capital in a Male-Dominated Political Field

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Brehony, Kevin J.

2009-01-01

This article examines the work of Lady Nancy Astor (1879-1964) in campaigning for nursery education and nursery schools in Britain from the late 1920s until the Second World War. Arguably no elected politician in England at any time, including the present, has identified themselves more closely with the cause of nursery schooling in Britain.…

Characteristics of the assistance to pilgrims in the National Sanctuary of Our Lady of Aparecida, São Paulo, Brazil, 2011-2014.

Science.gov (United States)

Carmo, Hercules de Oliveira; Valente, Tânia Cristina Oliveira

2017-01-01

to describe the characteristics of the health assistance for pilgrims visiting the National Sanctuary of Our Lady of Aparecida and to investigate health care strategies in periods of peak of religious tourism. a descriptive study using outpatient medical records from 2011 to 2014, for a detailed analysis for the month of October 2014 and the operational documents for health care in periods of mass events in the medical clinic of the Sanctuary. 95,011 people were assisted in the period, 2,266 in October 2014; the higher demand for assistance was from elderly individuals (33%), women (59%), and people from the Brazilian Southeast region (79%); there were no operational documents for specific actions for this period. the large number of visitors, associated with the frequency of mass events and the absence of an operating plan, may pose a serious public health scenario for that region.

Solution properties of a heteropolysaccharide extracted from pumpkin (Cucurbita pepo, lady godiva).

Science.gov (United States)

Song, Yi; Zhao, Jing; Ni, Yuanying; Li, Quanhong

2015-11-05

A water-soluble galactoglucofucomannan was extracted from pumpkin (Cucurbita pepo, lady godiva variety). GC-MS analysis indicated that the polysaccharide was composed of 1,6-linked-glucosyl, 1,2,6-linked-mannosyl, 1,3,6-linked-mannosyl, 1,2,6-linked-galactosyl, 1,2,6-linked-galactosyl, terminal fucosyl and terminal glucose. The solution properties of the polysaccharide were studied systematically by using size-exclusion chromatography combined with multi-angle laser light scattering, viscometry and dynamic light scattering at 25 °C. The weight average molecular masses (Mw), intrinsic viscosity [η], radius of gyration (Rg) and hydrodynamic radius (Rh) were found to be 12.7 × 10(5)g/mol, 780 ml/g, 68 nm and 116 nm, respectively. The fraction dimension and value of ρ (Rg/Rh) of the polysaccharide revealed that it existed in a sphere-like conformation in distilled water. The dependence of zero shear specific viscosity on the coil overlap parameter was analyzed using different models. Furthermore, degradation of samples upon autoclaving has been observed and quantified by intrinsic viscosity determination and SEC-MALLS. Copyright © 2015 Elsevier Ltd. All rights reserved.

Church ladies, good girls, and locas: stigma and the intersection of gender, ethnicity, mental illness, and sexuality in relation to HIV risk.

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Collins, Pamela Y; von Unger, Hella; Armbrister, Adria

2008-08-01

Inner city women with severe mental illness may carry multiple stigmatized statuses. In some contexts these include having a mental illness, being a member of an ethnic minority group, being an immigrant, being poor, and being a woman who does not live up to gendered expectations. These potentially stigmatizing identities influence both the way women's sexuality is viewed and their risk for HIV infection. This qualitative study applies the concept of intersectionality to facilitate understanding of how these multiple identities intersect to influence women's sexuality and HIV risk. We report the firsthand accounts of 24 Latina women living with severe mental illness in New York City. In examining the interlocking domains of these women's sexual lives, we find that the women seek identities that define them in opposition to the stigmatizing label of "loca" (Spanish for crazy) and bestow respect and dignity. These identities have unfolded through the additional themes of "good girls" and "church ladies". Therefore, in spite of their association with the "loca", the women also identify with faith and religion ("church ladies") and uphold more traditional gender norms ("good girls") that are often undermined by the realities of life with a severe mental illness and the stigma attached to it. However, the participants fall short of their gender ideals and engage in sexual relationships that they experience as disempowering and unsatisfying. The effects of their multiple identities as poor Latina women living with severe mental illness in an urban ethnic minority community are not always additive, but the interlocking effects can facilitate increased HIV risks. Interventions should acknowledge women's multiple layers of vulnerability, both individual and structural, and stress women's empowerment in and beyond the sexual realm.

The Israeli–Palestinian Separation Wall and the Assemblage Theory: The Case of the Weekly Rosary at the Icon of Our Lady of the Wall

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Elisa Farinacci

2017-06-01

Full Text Available In this work I analyse the ethnographic case study of the icon of Our Lady of the Wall as establishing a unique ritual landscape among the cement slabs of the Israeli–Palestinian Wall separating Jerusalem from Bethlehem. Although the Wall has been widely described as a technology of occupation on one side and as a device to ensure security on the other, through Latour’s concept of assemblages I unearth its agency in developing a Christian shrine. Through a decade of weekly recitations of the Rosary along the Wall near Checkpoint 300, the Elizabethan nuns of the Caritas Baby Hospital have been invoking Mary’s help to dismantle the Wall. This weekly ritual represents both political dissent against the bordering action enacted by the Wall, as well as giving visibility to the plea of the Palestinian Christian right to live in this territory in the face of their status as an ethno-religious minority.

Subtrochanteric Fracture In A Chinese Woman With Paget’s Disease Of Bone And On Long Term Bisphosphonate Therapy: Could It Be An Insufficiency Fracture?

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CK Lee

2011-03-01

Full Text Available Paget’s disease is common in Western countries but is very rare in Chinese populations. Although bisphosphonate has been widely used to treat symptomatic Paget’s disease, prolonged use may be associated with insufficiency fracture. We highlight this rare case of Paget’s disease in a Chinese lady who presented with an insufficiency fracture following long-term use of bisphosphonate.

Executive dysfunction correlates with caudate nucleus atrophy in patients with white matter changes on MRI: A subset of LADIS

DEFF Research Database (Denmark)

Macfarlane, Matthew Duncan; Looi, Jeffrey Chee Leong; Walterfang, Mark

2013-01-01

and falls in cross-sectional and follow-up studies. Frontostriatal (or frontosubcortical) brain circuits may serve many of these functions, with the caudate nuclei playing a role in convergence of cognitive functions. This study aimed to determine whether reduced caudate volume relates to cognitive...... functions (executive functions, memory functions and speed of processing) and WMC. We determined caudate nuclei volumes, through manual tracing, on a subgroup of the LADIS study (n=66) from four centres with baseline and 3-year follow-up MRI scans. Regression analysis was used to assess relationships...... between caudate volume, cognitive function and WMC. Severity of WMC did not relate to caudate volume. Smaller caudate volumes were significantly associated with poorer executive functioning at baseline and at 3 years, but were not associated with scores of memory or speed of processing. Thus, in patients...

De heroínas y mujeres. La trayectoria cinematográfica del personaje de Lady Marian

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Pérez Herrera, Gema

2016-06-01

Full Text Available The transformation of the role of women over the course of the 20th century can be seen particularly clearly in the cinema. The analysis of various cinematic representations of Lady Marian, Robin Hood’s romantic partner, reveals the transformation in the female from feminine to heroic between 1922 and the present. This change involves Marian adopting male roles and being included in scenes that were previously reserved for male characters, together with a progressive masculinisation of women. Analysing films made in different decades shows how cinema always conveys a contemporary message, reflecting human and cultural models in keeping with the sensitivities of its viewers.La revolución histórica de la mujer a lo largo del siglo XX ha tenido su correlato en un testigo de excepción: el cine. El análisis de varias representaciones cinematográficas de Lady Marian, protagonista femenina de la leyenda de Robin Hood, desde 1922 hasta algunas de las producciones más recientes permite señalar que se ha producido un cambio en el papel de lo femenino en lo heroico. Este cambio pasa por la adopción de roles y la inclusión en escenarios antaño reservados para el protagonismo masculino, así como por una progresiva masculinización de la mujer. El análisis de las representaciones realizadas en cada década del siglo XX permite también comprobar cómo el cine siempre proyecta un mensaje contemporáneo, reflejando en sus historias modelos humanos y culturales acordes con la sensibilidad de cada tiempo.

Never the Oval Office? From Eleanor Roosevelt to Michelle Obama—First Ladies and Their Social and Feminist Agenda

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Martina Kohl

2017-07-01

Full Text Available Prompted by the 2016 elections in the United States, women’s prospects in U.S. politics have received renewed attention among scholars and politically interested circles. Hillary Clinton, without any doubt one of the—if not the most qualified candidates for the Presidency ever, suffered an unexpected defeat on November 9th. Polls, experts, and the candidates were taken by surprise. Only in hindsight do critics claim to have known all along that Hillary Clinton’s defeat might have been foreseeable. As a former First Lady, Hillary Clinton belongs to a group of women in U.S. politics that at least have made it into the White House—though not as an elected representative of the administration. As different as these women have been, they all have one thing in common: the chance to shape policy.

Unexplained infertility as primary presentation of celiac disease, a case report and literature review

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Mohammadreza Ghadir

2011-01-01

Full Text Available Background: Celiac sprue (gluten sensitive enteropathy is an autoimmune disease which is hereditary and its pathology mainly bases on immunologic intolerance to gluten. It has a vast variety of signs and symptoms and its clinical features range from a silent disease to a typical gastrointestinal disorder. In this study we reviewed and summarized some other related issues about this disease and its relation with infertility.Case: The case is a 26 years old lady who had referred to a gynecologist because of infertility for 2 years and later it revealed that she has celiac sprue.Conclusion: Screening for its silent or subtle types especially among suspicious cases such as unexplained infertility seems to be a cost effective action. Meanwhile, in time administration of a gluten-free diet can lead to an almost complete cure

Lady Gaga - hiperrzeczywisty buntownik na sprzedaż jako propozycja tożsamościowa dla globalnej młodzieży

OpenAIRE

Wierzba, Paulina

2013-01-01

The article analyzes the phenomenon of Lady Gaga, one of the biggest modern culture icons. It shows the influence of the figure on the identity of global youth being constructed. Her image, videos, rhythm and song lyrics describe and express life experience of global teenagers, socializing them to their function in modern reality. The author tries to prove that in contemporary reality even a rebellion has become a product to sell. Youth idols who have undergone the way from counter-culture to...

Pictorial Real, Historical Intermedial. Digital Aesthetics and the Representation of History in Eric Rohmer’s The Lady and the Duke

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Tagliani Giacomo

2016-09-01

Full Text Available In The Lady and the Duke (2001, Eric Rohmer provides an unusual and “conservative” account of the French Revolution by recurring to classical and yet “revolutionary” means. The interpolation between painting and film produces a visual surface which pursues a paradoxical effect of immediacy and verisimilitude. At the same time though, it underscores the represented nature of the images in a complex dynamic of “reality effect” and critical meta-discourse. The aim of this paper is the analysis of the main discursive strategies deployed by the film to disclose an intermedial effectiveness in the light of its original digital aesthetics. Furthermore, it focuses on the problematic relationship between image and reality, deliberately addressed by Rohmer through the dichotomy simulation/illusion. Finally, drawing on the works of Louis Marin, it deals with the representation of history and the related ideology, in order to point out the film’s paradoxical nature, caught in an undecidability between past and present.

“Too Long in Foreign Parts”?: An Asian Reception to Cosmopolitanism in Henry James’s The American and The Portrait of a Lady

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Patricia Haseltine

2012-04-01

Full Text Available The works of Henry James with their attention to cosmopolitanism in the late nineteenth and early twentieth centuries provide valuable insight into contemporary expectations of cultural hybridity and globalism. This paper assesses the ways students studying English as a foreign language in Taiwan read the cultural exchanges between Americans and Europeans in James’s "The American" (1877 and "The Portrait of a Lady" (1881. It places the main attention upon how students evaluate James’s characters based upon their own attitudes toward cosmopolitanism, work and leisure, and women’s independence. Informed by the travel theory of Mary Louise Pratt (2008 and Homi Bhabha’s (1994 concept of the third space, it studies the negotiation and subversion of meaning in postcolonial and reverse-colonial contexts. The analysis of student responses reveals that in this culturally hybrid reading site, the limited consciousness technique of James generates judgments of characters’ potentialities based upon the students’ own values. Reconciling the cultural oppositions in the self to become a citizen of the world remains an ideal they do not see fully realized in James’s highly conflicted characters, and, as their own partial views attest, not realizable in their own lives.

Frequency and risk factors of hepatitis c virus in pregnant women attending military hospital rawalpindi

International Nuclear Information System (INIS)

Anwar, R.; Razzaq, K.; Imran, A.

2016-01-01

Objective: To determine the frequency of anti-Hepatitis C virus antibodies in pregnant ladies attending Military Hospital Rawalpindi and to analyze risk factors for disease acquisition in them. Study Design: Cross sectional study. Place and Duration of Study: Department of gynaecology and obstetrics Military Hospital Rawalpindi, from Feb 2013 to Jul 2013. Material and Methods: All pregnant ladies attending Military Hospital Rawalpindi were tested for anti HCV antibodies by third generation ELISA method and evaluation of potential risk factors for acquisition of HCV infection was done. Results: Six point ninety five percent of study population was found to be positive for anti HCV antibodies. Conclusion: Six point nine five percentage of study pregnant ladies were found to have anti HCV antibodies. These HCV positive pregnant women were more likely to have history of blood transfusion, therapeutic injection use and surgery. (author)

Frequency of significant three vessel coronary artery disease and left main stem disease in acute coronary syndrome patients having high LDL cholesterol level

International Nuclear Information System (INIS)

Zeb, S.; Achakzai, A.S.; Zeb, J.; Zeb, R.; Adil, M.; Jan, H.

2017-01-01

Objective: To calculate the frequency of significant three-vessel coronary artery and left main stem disease in patients presenting with acute coronary syndrome having high LDL cholesterol level. Methodology: This observational study was performed in Lady Reading Hospital, Peshawar, Pakistan from June 1, 2013 to December 31, 2013. All consecutive patients undergoing coronary angiography admitted with acute coronary syndrome within past 30 days and having LDL cholesterol more than 130mg/dl were included in the study. Demographic data was noted. The data was analyzed by using software SPSS version 16. Results: A total number of 206 patients were included in the study. Mean age was 51.25+-8.4 years. Of them, 139(67.5%) were male and 67(32.5%) female. Hypertension was found in 87(42.2%) patients, diabetes was found in 71(34.5%) patients, 56(27.2%) were smokers, family history of CAD was present in 39(18.9%) patients. The incidence of significant three vessel coronary artery disease was 52(25.2%) and left main stem disease were present in 15(7.2%). Out of 67(32.4%) with severe triple vessel and Left main stem disease, males were 51(76.1%) and females were 16(23.9%). Patients with significant three vessel and left main stem disease were more frequently males and younger. Conclusion: Patients having acute coronary syndrome with High LDL levels are more frequently have significant three vessel and Left main stem disease.

Lady Health Workers (LHWs as Flag Bearers for Children with Disabilities in Pakistan

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Ghazala Rafique

2012-06-01

Full Text Available Purpose: This study explores the perceptions, knowledge and attitudes of LHWs towards children with disabilities in Pakistan. It considers the feasibility of utilising the LHWs for prevention, early identification and management of disabilities for these children in the community.Methods: Two Focus Group Discussions (FGDs were conducted with 15 Lady Health Workers (LHWs, and two In Depth Interviews (IDIs with LHWs of both a semi-urban and a rural community of Pakistan.Results: LHWs were found to have major concerns and strong emotions regarding children with disabilities. They also revealed the insensitive attitude of community members towards these children. While they understood the major types and magnitude of disabilities better than lay persons, they lacked the knowledge to manage these disabilities. Consanguineous marriages were identified as the main cause of disabilities. LHWs reported that education and health facilities were lacking in semi-urban and rural areas, and demanded that the government provide these facilities for the children. They also expressed their willingness to work for these children, provided they had the approval of higher authorities and were given proper training.Conclusions: This qualitative exploratory study recommends that the existing primary health system be reviewed, and the possibility of introducing community based rehabilitation services, utilising LHWs’ services for children with disabilities, be examined. In this regard, it is imperative to assess the existing training modules of LHWs and to introduce modules on prevention, early identification, and management of children with disabilities. It is also necessary to employ mass media to spread awareness about persons with disabilities.

Nutrition in neonatal congenital heart disease

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Morgan CT

2013-09-01

Full Text Available Conall T Morgan,1 Anne Marie Shine,2 Colin J McMahon1 1Department of Pediatric Cardiology, 2Department of Clinical Nutrition and Dietetics, Our Lady's Children's Hospital Crumlin, Dublin, Republic of Ireland Abstract: There are 40,000 infants born in the USA with congenital heart disease annually. Achievement of adequate oral nutrition is difficult in this population. Malnutrition is common. Single ventricle physiology, the risk of necrotizing enterocolitis, and cardiopulmonary bypass prevent the establishment of normal oral feeding patterns. Improved nutrition results in improved surgical outcomes, lower mortality, and shorter hospital stay. In this review, we discuss the challenges this population faces. Keywords: necrotizing enterocolitis, malnutrition, growth failure, hypoplastic left heart

El poder de las redes sociales: la “mano invisible” del framing noticioso. El caso de #LadyProfeco.

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Luis Cesar Torres Nabel

2014-08-01

Full Text Available El artículo discute,  a partir del caso sobre #LadyProfeco en México, la hipótesis de la influencia de enmarcamiento (framing que están ejerciendo las redes sociales sobre los temas públicos importantes. Los resultados del análisis sobre el caso dan evidencia en contra de esta hipótesis ya que pese al crecimiento de las redes sociales y su visibilidad en la agenda pública, el 66.3% de la opinión que se vierte en hashtags y trending topics es producida por los  de periodistas, militantes partidistas y políticos profesionales que la establecían desde los medios tradicionales.

Analisis Pengaruh Hedonic Shopping Tendency Dan Visual Merchandising Terhadap Impulse Buying Dengan Positive Emotion Sebagai Variabel Intervaning Pada Area Ladies Matahari Department Store Tunjungan Plaza Surabaya

OpenAIRE

Yanthi, Devi

2014-01-01

This research tried to determine what factors are causing consumers to do impulse buying in the area of ladies at Matahari Department Store. Variables examined in this research include hedonic shopping tendency and visual merchandising as the independent variable, positive emotion as the intervening variable, and impulse buying as the dependent variable. The sample used amounted 100 rerspondents. By using PLS-SEM analysis technique, demonstrated that through positive emotion variables, hedoni...

27 February 2012 - First Lady of Mexico, M. Zavala Gómez del Campo, welcomed by Adviser J. Salicio Diez withe ALICE Management and Mexican Users at LHC Point 2 and signing the guest book with CERN Director-General R. Heuer.

CERN Multimedia

Maximilien Brice

2012-01-01

27 February 2012 - First Lady of Mexico, M. Zavala Gómez del Campo, welcomed by Adviser J. Salicio Diez withe ALICE Management and Mexican Users at LHC Point 2 and signing the guest book with CERN Director-General R. Heuer.

Ranking prediction model using the competition record of Ladies Professional Golf Association players.

Science.gov (United States)

Chae, Jin Seok; Park, Jin; So, Wi-Young

2017-07-28

The purpose of this study was to suggest a ranking prediction model using the competition record of the Ladies Professional Golf Association (LPGA) players. The top 100 players on the tour money list from the 2013-2016 US Open were analyzed in this model. Stepwise regression analysis was conducted to examine the effect of performance and independent variables (i.e., driving accuracy, green in regulation, putts per round, driving distance, percentage of sand saves, par-3 average, par-4 average, par-5 average, birdies average, and eagle average) on dependent variables (i.e., scoring average, official money, top-10 finishes, winning percentage, and 60-strokes average). The following prediction model was suggested:Y (Scoring average) = 55.871 - 0.947 (Birdies average) + 4.576 (Par-4 average) - 0.028 (Green in regulation) - 0.012 (Percentage of sand saves) + 2.088 (Par-3 average) - 0.026 (Driving accuracy) - 0.017 (Driving distance) + 0.085 (Putts per round)Y (Official money) = 6628736.723 + 528557.907 (Birdies average) - 1831800.821 (Par-4 average) + 11681.739 (Green in regulation) + 6476.344 (Percentage of sand saves) - 688115.074 (Par-3 average) + 7375.971 (Driving accuracy)Y (Top-10 finish%) = 204.462 + 12.562 (Birdies average) - 47.745 (Par-4 average) + 1.633 (Green in regulation) - 5.151 (Putts per round) + 0.132 (Percentage of sand saves)Y (Winning percentage) = 49.949 + 3.191 (Birdies average) - 15.023 (Par-4 average) + 0.043 (Percentage of sand saves)Y (60-strokes average) = 217.649 + 13.978 (Birdies average) - 44.855 (Par-4 average) - 22.433 (Par-3 average) + 0.16 (Green in regulation)Scoring of the above five prediction models and the prediction of golf ranking in the 2016 Women's Golf Olympic competition in Rio revealed a significant correlation between the predicted and real ranking (r = 0.689, p ranking prediction model using LPGA data may help coaches and players to identify which players are likely to participate in Olympic and World competitions, based

'Our queen of hearts' - the glorification of Lady Diana Spencer: a critical appraisal of the glorification of celebrities and new pilgrimage

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Céline Grünhagen

2010-01-01

Full Text Available Religiosity and spirituality respectively have always been and will be subject to change. The emergence of the manifold forms of new religious and spiritual movements in the last century includes a variety of cult-like vener­ations of specific individuals, such as politicians (e.g. Mao, Lenin and modern idols (e.g. Elvis Presley, Princess Diana, Michael Jackson, who are glorified like saints. Devotees gather annually for memorials of their departed idols or travel­ long distances to visit the tomb, former home, etc. of a specific person to pay tribute to him or her. Due to the motivations of these devotees, the trouble they take, the practices and the tangible emotionality that are connected with this phenomenon, it can be considered a form of pilgrimage. This article presents some thoughts about the glorification of celebrities which leads to these considerable forms of cult and pilgrimage, using as an example the case of Lady Diana Frances Spencer (d. 1997.

Lady Morgan in Italy: A Traveller with an Agenda

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Donatella Abbate Badin

2016-06-01

Full Text Available Lady Morgan (née Sydney Owenson was a professional Irish travellerand travel-writer, who spent over a year on the peninsula. The travelogueItaly (1821 she was commissioned to write on the basis of the reputationshe had acquired as a novelist (e.g. The Wild Irish Girl, 1806 anda socio-political writer (France, 1817, left a mark on Italy and on theunderstanding of Italy in Great Britain. Her writings, in fact, helpeddisseminate the ideal of a unified Italy and influence British and Irishpublic opinion in favour of Italy’s aspirations to cast off foreign or domesticautocratic rule. Moreover, she used her travelogue to serve thecause of Ireland disguising a patriotic message about her home countryunder her many sallies about nationalism and the right to self-determinationconcerning Italy. The political impact of her book, unusualfor a travel account written by a woman, was enhanced by Morgan’sradical ideology, the gender bias of her observations and her originalmethods. The present article purposes to examine Morgan’s double,feminine and masculine, approach of mixing solid documentation withapparently frivolous notes originating in the feminine domain of societynews, commentary on the domestic scene and emotional reporting onsocial and historical events. Distrusting male-authored official history,Morgan gave a central place in her work to the informal sources fromwhich she gathered her insights about Italy. Analysing how she came toobtain the contemporary input for elaborating her ideas will be the aimof this chapter which will dwell on the more worldly aspects of Morgan’ssojourn in the peninsula focussing on the company she kept, theactivities she partook of, the events of a domestic nature she witnessed.

« The glittering game » : le jeu des choses dans A Lost Lady et My Mortal Enemy de Willa Cather

OpenAIRE

Manresa, Céline

2014-01-01

Dans A Lost Lady et My Mortal Enemy, Willa Cather confère aux choses un rôle étonnamment actif au cœur de l’intrigue et un relief inédit au sein de l’écriture. Loin de demeurer tapies dans l’ombre ou figées dans l’arrière-plan des décors, les choses investissent pleinement le devant de la scène diégétique et narrative. Du costume aux détails de la décoration, les choses gouvernent les jeux de modelage réciproque entre l’habitant et l’habitat, visant à transformer l’intérieur des maisons en un...

Prevalence of diabetes mellitus among obese and non-obese patients with coronary artery disease

International Nuclear Information System (INIS)

Khan, S.B.; Rehman, H.U.; Hafeezullah, M.; Gul, A.M.

2010-01-01

Background: Globally, obesity is now recognised as an epidemic. The degree of obesity is proportional to the rate of development of cardiovascular diseases, hence, resulting in a dramatic increase in morbidity and mortality. Apart from obesity, diabetes mellitus is another well recognised risk factor contributing to coronary artery disease. The precise prevalence of obesity-related diabetes varies with age, race and gender; and is yet unknown in our population. We therefore, carried out study with the aim to determine the prevalence of diabetes mellitus in obese and non-obese patients with diagnosed coronary artery disease. Methods: This hospital based cross-sectional comparative study was conducted in Cardiology Department of Postgraduate Medical Institute, Lady Reading Hospital, Peshawar, from March 15, 2005 to May 30, 2006. A total of 200 patients with diagnosed coronary artery disease were enrolled, 100 were classified as obese and 100 as non-obese. Results: Among these, 139 patients were male and 61 female. A total of 88 were found to be diabetic, 54 of these were obese and 34 non-obese (p =0.004). Conclusion: Diabetes mellitus was significantly more frequent among obese patients with coronary artery disease as compared to non obese patients with coronary artery disease. (author)

Responses of growth of lady's fingers (Abelmoschus esculentus L.) to different treatments methods of dairy wastewater.

Science.gov (United States)

Al-Dulaimi, Rana Ibrahim; Ismail, Norli; Ibrahim, Mahamad H

2014-01-01

Water is one of the most important precious resources found on the earth, and are most often affected by anthropogenic activities and by industry. Pollution caused by human beings and industries is a serious concern throughout the world. Population growth, massive urbanization, rapid rate of industrialization and modern techniques in agriculture have accelerated water pollution and led to the gradual deterioration of its quality. A large quantity of waste water disposed of at sea or on land has caused environmental problems which have led to environmental pollution, economic losses and chemical risks caused by the wastewater, and its impact on agriculture. However, waste water which contain nutrients and organic matter has possible advantages for agricultural purposes. Therefore, the presented study was undertaken to assess the impact of Dairy Effluent (treated and untreated waste water) on seed germination, seedling growth, dry matter production and the biochemical parameters of lady's fingers (Abelmoschus esculentus L.). A field experiment in a green house was conducted to use raw and treated dairy wastewater for watering lady's fingers (Abelmoschus esculentus L.). The plants were watered using (WW) raw dairy wastewater, (T1) chemicals treatment, (T2) physical treatment, (T3) dilution method treatment and tap water (TW) in pot experiments. Ten plants of each treatment /3 replicate were randomly selected and labelled for the collection of data. The data was collected sequentially, starting with chlorophyll content pre-harvest, vegetative qualities (shoot, root and seedling length) and dry matter quality (shoot and root dry matter) pos-tharvest. The effect was seen on the germination seed and growth of the plant. The results showed inhibitory effect from dairy effluent (WW) on seed germination and plant growth. Treatment with chemicals showed statistically significant differences with other treatments. Chemical treatment (TC2) at 20 mg/L Al2(SO4)3 and pH 6

“Gay, Elderly, Self-Standing Lady From the Castle Rauhenstein”: Elements of Romantic Friendship in the Works of Pavlina Pajk

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Nataša Velikonja

2014-06-01

Full Text Available Text analyzes the work of novelist and poet Pavlina Pajk (1854–1901, who is considered to be “the first lady of Slovenian women’s novel”, but most of the time her opus was disregarded and misunderstood. Pavlina Pajk was ranked, among other things, among those “inappropriate, excessively emancipated women”, “adherents of George Sand”, as signified by feminists at the turn of the 19th to 20th century, who with their life and work raised more radical class, status, gender and sexual, in short, identity issues as it was established by the then dominant national canon. Among other things, Pavlina Pajk advocated sexual relativity and opposed gender and sexual conventions of her time. In many of her works we can find elements of romantic friendship, specific form of love between women, in American and European societies quite frequent until the early 20th century. Thus we can gain an insight into the pre-homosexual or pre-lesbian discourse of the 19th century literature in Slovenian language.

Structural analysis of jewelry from the Moche tomb of the `lady of Cao' by X-ray digital radiography

Science.gov (United States)

Azeredo, S. R.; Cesareo, R.; Franco, R.; Fernandez, A.; Bustamante, A.; Lopes, R. T.

2018-04-01

Nose ornaments from the tomb of the `Lady of Cao', a mummified woman representative of the Moche culture and dated to the third-or-fourth century AD, were analyzed by X-ray digital radiography. These spectacular gold and silver jewels are some of the most sophisticated metalworking ever produced in ancient America. The Mochecivilization flourished along the north coast of present-day Peru, between the Andes and the Pacific Ocean, approximately between 100 and 600 AD. The Moche were very sophisticated artisans and metal smiths, being considered the finest producers of jewels and artifacts of the region. A portable X-ray digital radiography (XDR) system consisting of a flat panel detector with high resolution image and a mini X-ray tube was used for the structural analysis of the Moche jewels aiming at inferring different joining methods of the silver-gold sheets. The radiographic analysis showed some differences in the joint of the silver-and-gold sheets. Presence of filler material and adhesive for joining the silver-and-gold sheets was visible as well as silver-gold junctions without filler material (or with a material invisible in radiography). Furthermore, the technique demonstrated the advantage of using a portable XDR micro system when the sample cannot be brought to the laboratory.

Long-distance autumn migration across the Sahara by painted lady butterflies: exploiting resource pulses in the tropical savannah.

Science.gov (United States)

Stefanescu, Constantí; Soto, David X; Talavera, Gerard; Vila, Roger; Hobson, Keith A

2016-10-01

The painted lady, Vanessa cardui, is a migratory butterfly that performs an annual multi-generational migration between Europe and North Africa. Its seasonal appearance south of the Sahara in autumn is well known and has led to the suggestion that it results from extremely long migratory flights by European butterflies to seasonally exploit the Sahel and the tropical savannah. However, this possibility has remained unproven. Here, we analyse the isotopic composition of butterflies from seven European and seven African countries to provide new support for this hypothesis. Each individual was assigned a geographical natal origin, based on its wing stable hydrogen isotope (δ 2 H w ) value and a predicted δ 2 H w basemap for Europe and northern Africa. Natal assignments of autumn migrants collected south of the Sahara confirmed long-distance movements (of 4000 km or more) starting in Europe. Samples from Maghreb revealed a mixed origin of migrants, with most individuals with a European origin, but others having originated in the Sahel. Therefore, autumn movements are not only directed to northwestern Africa, but also include southward and northward flights across the Sahara. Through this remarkable behaviour, the productive but highly seasonal region south of the Sahara is incorporated into the migratory circuit of V. cardui. © 2016 The Author(s).

Of Lady-killers and ‘Men Dressed As Women’: Soap Opera, Scapegoats and the Mexico City Police Department

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Vek Lewis

2008-02-01

Full Text Available Over two days in October 2005, police in Mexico City conducted a series of raids on male-to-female transgender (travesti prostitutes working in the streets. The motive of the investigation was not related to sex work at all, but rather, the hunt for a serial killer responsible for the deaths of elderly women between 2003 and 2005. With few leads apart from reports by a couple of eyewitnesses that they had seen ‘a man dressed as a woman’ enter the houses of the victims, the Chief Public Prosecutor announced that the killer could be a travesti. On January 25, 2006, the ‘lady-killer’ was finally discovered to be neither a ‘man dressed as a woman’, nor a travesti. The suspect, a female former lucha libre wrestler, Juana Barraza, was taken into custody. In the period leading up to the October raids, Mexico’s chief television channel, Televisa, finished up the season of its popular soap, La Madrastra, with a plot line that features a man who dresses as a woman to disguise his usual male identity and kill his female victims. This paper examines the case, looking at the influence of the soap opera narrative in the profiling of travestis as suspect ‘men dressed as women’. It draws on studies of soap opera and mass media forms in Mexican society, as well as the work of transgender theory in understanding how crossgender identities are circumscribed by discourse.

Virtuous colours for Mary. Identification of lapis lazuli, smalt and cochineal in the Andean colonial image of Our Lady of Copacabana (Bolivia)

Science.gov (United States)

Tomasini, Eugenia P.; Marte, Fernando; Careaga, Valeria P.; Landa, Carlos Rúa; Siracusano, Gabriela

2016-01-01

The image of Our Lady of Copacabana, a gilded polychrome sculpture carved in maguey wood in 1583, is one of the most important devotions in the Americas. In former research, we have identified the use of gypsum, Armenian bole, cerussite and atacamite in its polychromy. In this study, a red sample taken from the Virgin's tunic and a blue sample extracted from the cloak have been analysed with the aim to identify both pigments and offer insights into the painting technique. Analysis by micro-Raman spectroscopy complemented with scanning electron microscopy–energy dispersive spectroscopy and high-performance liquid chromatography allowed the identification of carmine lake in the red sample. Analysis by micro-Raman spectroscopy of the surface of the blue sample and its cross section showed the presence of smalt—the blue-glass pigment—over a cerussite layer, bathed by a very thin ultramarine layer—from a probable native origin—following a pictorial tradition that would last even until the eighteenth century. This is the first time that lapis lazuli has been scientifically identified in a Spanish American colonial painted layer. This article is part of the themed issue ‘Raman spectroscopy in art and archaeology’. PMID:27799431

Prevalence of hypertension among obese and non-obese patients with coronary artery disease

International Nuclear Information System (INIS)

Khan, S.B.; Noor, L.; Awan, Z.A.; Shahab-ud-Din; Shah, S.S.

2010-01-01

Background: Globally, obesity is now recognised as an epidemic. The degree of obesity is proportional to the rate of development of cardiovascular diseases, hence, resulting in a dramatic increase in morbidity and mortality. Apart from obesity, hypertension is another well recognised risk factor contributing to coronary artery disease (CAD). The precise prevalence of obesity-related hypertension varies with age, race and gender; and is yet unknown in our population. The objective of this study was to determine the prevalence of hypertension in obese and non-obese patients with diagnosed CAD. Methods: This hospital based descriptive study was conducted in Cardiology Department of Postgraduate Medical Institute, Lady Reading Hospital, Peshawar from March 15, 2007 to May 30, 2008. A total of 200 patients with diagnosed CAD were enrolled, 100 were found obese and 100 non-obese. Results: Among these, a total of 111 (55.5%) were found to be hypertensive, 66 (59.46%) of these were obese and 45 (40.54%) non-obese (p=0.003). Conclusion: Obese patients with CAD had significantly more frequent hypertension. (author)

Purpura fulminans in a patient with mixed connective tissue disease.

LENUS (Irish Health Repository)

Murad, Aizuri A

2013-01-01

A 43-year-old lady was admitted to the intensive care unit with sepsis. She had a history of mixed connective tissue disease, Raynaud\\'s syndrome and hypothyroidism. 2 days later, she developed a purpuric rash on her face and extremities with a livedoid background. Few days later, her distal fingers and toes became gangrenous which then had to be amputated. Laboratory investigations showed that she was coagulopathic and had multiple organ dysfunctions. Antiphospholipid antibodies were negative; however, protein C and antithrombin III levels were low. A skin biopsy showed fibrinoid necrosis in the vessel wall with microthrombi and red-cell extravasation. A diagnosis of purpura fulminans was made.

Histopathological pattern of soft tissues tumors and tumour like lesions in the pathology department of lady reading hospital peshawar, pakistan

International Nuclear Information System (INIS)

Sajjad, M.; Ahmad, F.

2016-01-01

Soft tissues tumours are tumours of mesenchymal origin excluding epithelial, skeletal tissue, reticuloendothelial system, brain coverings and solid viscera of the body. The objective of this study was to know the histopathological pattern of soft tissues tumours in the Pathology Department of Lady Reading Hospital Peshawar Khyber Pakhtunkhwa Pakistan. Methods: This descriptive study was conducted on retrospective data from January 2009 to December 2013. All the soft tissues biopsy specimens were received in 10% formalin, labelled, gross performed, sections processed in alcohol, xylene, wax, block prepared, frozen, microtome sections taken and processed for H and E staining, mounted and reported by a Histopathologist. The inclusion criteria was any sufficient soft tissue tumour biopsy specimen of any age, sex, location in body whereas the exclusion criteria was autolysed biopsy specimen. A minimum of four and maximum of eight sections and 5 micron thick were taken from each specimen. Results: A total of 267 soft tissues tumours biopsy specimens were received in the pathology laboratory with age range of 01 to 75 years, with mean age of 30.68+-17.71 years. Male to female ratio was 1.13:1. Amongst the total, benign tumours were 176 (65.91%). Haemangioma, 73 (27.3%) was the commonest tumours followed by lipomas 41 (15.4%) cases. Amongst the total malignant tumours, i.e., 91 (34.08%), rhabdomyosarcoma, 35 (13.1%) was the commonest tumour followed by angiosarcoma 14 (5.2%) cases. Conclusion: Haemangioma is the commonest benign tumour and rhabdomyosarcoma is the commonest malignant tumour in this study. (author)

MEDEIA, LADY MACBETH, DELIA E TRAMELL: APROXIMAÇÕES INTERARTES SOB A FIGURA DA BRUXA

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Márcio Henrique Muraca

2014-10-01

Full Text Available O artigo pretende aproximar a figura popular da bruxa ao mito da mulher funesta, símbolo da ameaça da ordem política pela perturbação da consciência moral de uma época. Além da crença da bruxaria e dos mitos em torno da mulher, é possível chegar ao embate entre público e privado, político e psicológico. Quatro personagens femininas consagradas ilustram a tese que aqui se pretende: Medeia (Eurípedes – teatro grego, Lady Macbeth (Shakespeare – teatro moderno, Delia (Cortázar – literatura latino-americana, séc. XX e Catherine Tramell (Osborne – obra fílmica blockbuster e livro baseado no script. O princípio teórico norteador deste estudo é o das relações de poder, de Michel Foucault, sobretudo por meio da obra Microfísica do Poder. Quanto à questão da bruxa/bruxaria, o artigo vale-se de Pensando em Demônios, de Stuart Clark.

MRI-defined subcortical ischemic vascular disease: baseline clinical and neuropsychological findings. The LADIS Study

DEFF Research Database (Denmark)

Jokinen, Hanna; Kalska, Hely; Ylikoski, Raija

2009-01-01

of global cognitive function, psychomotor speed, attention and executive functions, verbal fluency, and working memory. CONCLUSION: In this population of nondisabled older adults with WML, SIVD was related to specific clinical and functional characteristics. Neuropsychological features included psychomotor...... slowing as well as deficits in attention and executive functions....

Effect of acetylation on antioxidant and cytoprotective activity of polysaccharides isolated from pumpkin (Cucurbita pepo, lady godiva).

Science.gov (United States)

Song, Yi; Yang, Yang; Zhang, Yuyu; Duan, Liusheng; Zhou, Chunli; Ni, Yuanying; Liao, Xiaojun; Li, Quanhong; Hu, Xiaosong

2013-10-15

Acetylation of pumpkin (Cucurbita pepo, lady godiva variety) polysaccharide using acetic anhydride with pyridines as catalyst under different conditions was conducted to obtain different degrees of acetylation on a laboratory scale. Furthermore, antioxidant activities and cytoprotective effects of pumpkin polysaccharide and its acetylated derivatives were investigated employing various established in vitro systems. Results showed that addition of pyridine as catalyst could increase the degree of substitution, whereas volume of acetic anhydride had little effect. The acetylated polysaccharides in DPPH scavenging radical activity assay, superoxide anion radical activity assay and reducing power assay exhibited higher antioxidant activity than that of unmodified polysaccharide. H2O2-induced oxidative damages on rat thymic lymphocyte were also prevented by pumpkin polysaccharide and its acetylated derivatives and the derivatives presented higher protective effects. On the whole, acetylated polysaccharide showed relevant antioxidant activity both in vitro and in a cell system. Copyright © 2013 Elsevier Ltd. All rights reserved.

Autour de Nikolaï Leskov et de William Shakespeare : Lady Macbeth sibérienne d'Andrzej Wajda

OpenAIRE

Géry, Catherine

2016-01-01

Lady Macbeth sibérienne d’Andrzej Wajda est un film qui joue constamment de codes plus ou moins conflictuels : cinéma et théâtre (William Shakespeare), mais aussi cinéma et opéra (Dmitri Chostakovitch), cinéma et conte oral (Nikolaï Leskov). Cultivant le dialogue entre les genres et les discours esthétiques, il est également au croisement des cultures et des époques. Dans ce chapitre, j’envisage la théâtralité du film de Wajda selon plusieurs de ses définitions possibles : la théâtralité comm...

The Age of Studies and Reports: Selected Elements Concerning the Background of Encounters Defining the Power of Education

Science.gov (United States)

Tašner, Veronika; Gaber, Slavko

2016-01-01

In the present paper, we discuss the time before the "age of reports". Besides the Coleman Report in the period of Coleman, the Lady Plowden Report also appeared, while there were important studies in France (Bourdieu & Passeron, 1964; Peyre, 1959) and studies that inaugurated comprehensive education in Nordic countries. We focus on…

H.E. Dr Danilo Türk President of the Republic of Slovenia (second from right) visiting the ATLAS detector with, from left to right, Ambassador A. Logar, Spokesperson F. Gianotti, Director-General R. Heuer, First Lady B. Miklič Türk and ATLAS Slovenian national contactperson M. Mikuz.

CERN Multimedia

Maximilien Brice

2009-01-01

H.E. Dr Danilo Türk President of the Republic of Slovenia (second from right) visiting the ATLAS detector with, from left to right, Ambassador A. Logar, Spokesperson F. Gianotti, Director-General R. Heuer, First Lady B. Miklič Türk and ATLAS Slovenian national contactperson M. Mikuz.

Television's "crazy lady" trope: female psychopathic traits, teaching, and influence of popular culture.

Science.gov (United States)

Cerny, Cathleen; Friedman, Susan Hatters; Smith, Delaney

2014-04-01

This article describes notable illustrations of female psychopathy on modern television to review various characters that will have utility in teaching students about female psychopathy in distinction to male psychopathy and to encourage consideration of the potential effects that viewing these countless examples may have on a generation of young women. The authors use examples from soap operas, crime procedurals, reality television, fantasy, comedies, and young adult programs to illustrate gender differences in psychopathy and make specific teaching points. They also review the research literature related to popular culture's impact on behavior and gender roles. Gender differences in real-world psychopathy are mirrored in television portrayals. For example, female psychopaths, on TV and in reality, use sexual manipulation, demonstrate unstable emotions, and employ social aggression to achieve their ambitions. The examples of female psychopathic traits are prevalent on TV and easily accessible for teaching purposes. Research does give some support for a popular culture impact on behavior and gender roles. As compared to male psychopathy, female psychopathy is less recognized, and there are some notable differences in how the psychopathic traits manifest. Television provides myriad teaching examples that can highlight the gender distinctions such as use of sexual manipulation, emotional instability, and social aggression. Research suggests that the prevalence of "crazy ladies" on television may be negatively impacting gender stereotypes and normalizing bad behavior in young women.

Dynamic distribution patterns of ribosomal DNA and chromosomal evolution in Paphiopedilum, a lady's slipper orchid

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Albert Victor A

2011-09-01

Full Text Available Abstract Background Paphiopedilum is a horticulturally and ecologically important genus of ca. 80 species of lady's slipper orchids native to Southeast Asia. These plants have long been of interest regarding their chromosomal evolution, which involves a progressive aneuploid series based on either fission or fusion of centromeres. Chromosome number is positively correlated with genome size, so rearrangement processes must include either insertion or deletion of DNA segments. We have conducted Fluorescence In Situ Hybridization (FISH studies using 5S and 25S ribosomal DNA (rDNA probes to survey for rearrangements, duplications, and phylogenetically-correlated variation within Paphiopedilum. We further studied sequence variation of the non-transcribed spacers of 5S rDNA (5S-NTS to examine their complex duplication history, including the possibility that concerted evolutionary forces may homogenize diversity. Results 5S and 25S rDNA loci among Paphiopedilum species, representing all key phylogenetic lineages, exhibit a considerable diversity that correlates well with recognized evolutionary groups. 25S rDNA signals range from 2 (representing 1 locus to 9, the latter representing hemizygosity. 5S loci display extensive structural variation, and show from 2 specific signals to many, both major and minor and highly dispersed. The dispersed signals mainly occur at centromeric and subtelomeric positions, which are hotspots for chromosomal breakpoints. Phylogenetic analysis of cloned 5S rDNA non-transcribed spacer (5S-NTS sequences showed evidence for both ancient and recent post-speciation duplication events, as well as interlocus and intralocus diversity. Conclusions Paphiopedilum species display many chromosomal rearrangements - for example, duplications, translocations, and inversions - but only weak concerted evolutionary forces among highly duplicated 5S arrays, which suggests that double-strand break repair processes are dynamic and ongoing. These

The Construction of Epistolary Identity in a Gentry’s Communication Network of the Seventeenth Century: The Case of Jane Lady Cornwallis Bacon

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Gabriella Del Lungo Camiciotti

2014-04-01

Full Text Available There has recently been increasing scholarly interest in early modern correspondence and specifically also in women’s letter writing and reading. Starting from the late Middle Ages familiar responsibilities and domestic obligations led many women to write to their absent husbands or other relatives to exchange health news and inform them about family affairs. It is however in the early modern period that corresponding with relatives and friends became a widespread social practice ranging from official to familiar and personal correspondence; in this period female literacy increased thus allowing growing numbers of women to write and read their own letters. A growing number of female voices can thus be heard depicting early modern social life. The article focuses on a neglected aspect of women’s correspondence: it investigates not the sender’s epistolary identity, but that of the recipient through the analysis of the personal correspondence of Lady Cornwallis Bacon. The main theme of the article is to show how the epistolary identity of an early modern gentlewoman was constructed by her correspondents. It is assumed that modes of communicating information and achieving a specific goal through letters varied not only according to the relationship connecting the correspondents but also the purpose and content of letters. 

Is blinking of the eyes affected in extrapyramidal disorders? An interesting observation in a patient with Wilson disease.

Science.gov (United States)

Verma, Rajesh; Lalla, Rakesh; Patil, Tushar B

2012-11-27

Blinking of eye is a routine human activity which seldom attracts any attention of clinicians in health and disease. There is experimental evidence that blink rate is affected in extrapyramidal disorders affecting the balance of these neurotransmitters. However, no observations regarding blink rate in Wilson disease (WD) have been reported previously. We report a patient of WD with an increased spontaneous blink rate. A 24-year-old lady presented complaining of tremulousness of both upper limbs and head for 2 years, dysphagia and difficulty in speaking for 1.5 years and abnormal behaviour for last 1 year. We observed that her blink rate at rest was 32/min. Serum ceruloplasmin level was low (0.08 g/l). The patient was started on therapy with D-penicillamine, zinc sulphate, levodopa-carbidopa and trihexiphenidyl. At 1-month follow-up, patient's tremors were markedly decreased and blink rate at rest was decreased to 12/min.

Quality of care of treatment for uncomplicated severe acute malnutrition provided by lady health workers in Pakistan.

Science.gov (United States)

Rogers, Eleanor; Ali, Muhammad; Fazal, Shahid; Kumar, Deepak; Guerrero, Saul; Hussain, Imtiaz; Soofi, Sajid; Alvarez Morán, Jose Luis

2018-02-01

To assess the quality of care provided by lady health workers (LHW) managing cases of uncomplicated severe acute malnutrition (SAM) in the community. Cross-sectional quality-of-care study. The feasibility of the implementation of screening and treatment for uncomplicated SAM in the community by LHW was tested in Sindh Province, Pakistan. An observational, clinical prospective multicentre cohort study compared the LHW-delivered care with the existing outpatient health facility model. LHW implementing treatment for uncomplicated SAM in the community. Oedema was diagnosed conducted correctly for 87·5 % of children; weight and mid upper-arm circumference were measured correctly for 60·0 % and 57·4 % of children, respectively. The appetite test was conducted correctly for 42·0 % of cases. Of all cases of SAM without complications assessed during the study, 68·0 % received the correct medical and nutrition treatment. The proportion of cases that received the correct medical and nutrition treatment and key counselling messages was 4·0 %. This quality-of-care study supports existing evidence that LHW are able to identify uncomplicated SAM, and a majority can provide appropriate nutrition and medical treatment in the community. However, the findings also show that their ability to provide the complete package with an acceptable level of care is not assured. Additional evidence on the impact of supervision and training on the quality of SAM treatment and counselling provided by LHW to children with SAM is required. The study has also shown that, as in other sectors, it is essential that operational challenges are addressed in a timely manner and that implementers receive appropriate levels of support, if SAM is to be treated successfully in the community.

Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

Science.gov (United States)

Moutsopoulos, Niki M; Chalmers, Natalia I; Barb, Jennifer J; Abusleme, Loreto; Greenwell-Wild, Teresa; Dutzan, Nicolas; Paster, Bruce J; Munson, Peter J; Fine, Daniel H; Uzel, Gulbu; Holland, Steven M

2015-03-01

Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurrent life threatening infections and severe oral disease (periodontitis). Microbial communities in the local environment (subgingival plaque) are thought to be the triggers for inflammatory periodontitis, yet little is known regarding the microbial communities associated with LAD-I periodontitis. Here we present the first comprehensive characterization of the subgingival communities in LAD-I, using a 16S rRNA gene-based microarray, and investigate the relationship of this tooth adherent microbiome to the local immunopathology of periodontitis. We show that the LAD subgingival microbiome is distinct from that of health and Localized Aggressive Periodontitits. Select periodontitis-associated species in the LAD microbiome included Parvimonas micra, Porphyromonas endodontalis, Eubacterium brachy and Treponema species. Pseudomonas aeruginosa, a bacterium not typically found in subgingival plaque is detected in LAD-I. We suggest that microbial products from LAD-associated communities may have a role in stimulating the local inflammatory response. We demonstrate that bacterial LPS translocates into the lesions of LAD-periodontitis potentially triggering immunopathology. We also show in in vitro assays with human macrophages and in vivo in animal models that microbial products from LAD-associated subgingival plaque trigger IL-23-related immune responses, which have been shown to dominate in patient lesions. In conclusion, our current study characterizes the subgingival microbial communities in LAD-periodontitis and supports their role as triggers of disease pathogenesis.

Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

Directory of Open Access Journals (Sweden)

Niki M Moutsopoulos

2015-03-01

Full Text Available Leukocyte Adhesion Deficiency I (LAD-I is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurrent life threatening infections and severe oral disease (periodontitis. Microbial communities in the local environment (subgingival plaque are thought to be the triggers for inflammatory periodontitis, yet little is known regarding the microbial communities associated with LAD-I periodontitis. Here we present the first comprehensive characterization of the subgingival communities in LAD-I, using a 16S rRNA gene-based microarray, and investigate the relationship of this tooth adherent microbiome to the local immunopathology of periodontitis. We show that the LAD subgingival microbiome is distinct from that of health and Localized Aggressive Periodontitits. Select periodontitis-associated species in the LAD microbiome included Parvimonas micra, Porphyromonas endodontalis, Eubacterium brachy and Treponema species. Pseudomonas aeruginosa, a bacterium not typically found in subgingival plaque is detected in LAD-I. We suggest that microbial products from LAD-associated communities may have a role in stimulating the local inflammatory response. We demonstrate that bacterial LPS translocates into the lesions of LAD-periodontitis potentially triggering immunopathology. We also show in in vitro assays with human macrophages and in vivo in animal models that microbial products from LAD-associated subgingival plaque trigger IL-23-related immune responses, which have been shown to dominate in patient lesions. In conclusion, our current study characterizes the subgingival microbial communities in LAD-periodontitis and supports their role as triggers of disease pathogenesis.

Creutzfeldt-Jakob Disease as a Cause of Cognitive Decline and Seizures in the Elderly: Diagnostic Pointers and Strategy for Investigation

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R. Williams

2011-01-01

Full Text Available Cognitive decline affects one in twenty people over the age of 65. There is often a paucity of clues as to the underlying pathology, and while the diagnosis will usually prove to be either Alzheimer’s disease or vascular dementia, there may be clinical features suggesting rarer alternatives. This case of a 71-year-old lady with a 3-month history of progressive cognitive decline illustrates clinical features suggestive of Creutzfeltd-Jakob disease such as rapid decline in conscious level and myoclonic jerking. Diagnosis was confirmed by 3 means: (1 Electroencephalogram demonstrating periodic sharp wave complexes, (2 MRI brain showing cortical ribboning and high signal in the caudate nucleus, and (3 presence of protein S100 and protein14-3-3 in the cerebrospinal fluid. Postmortem brain histology confirmed a typical spongiform encephalopathy. Establishing an underlying aetiology is dementia is important not only for prognostic reasons but in order to detect potentially reversible causes. In cases of an atypical dementing illness our proposed investigations may assist in confirming or excluding underlying Creutzfeltd-Jakob disease.

The Meeting with Guanyin, the Goddess of Mercy: A Case Study of Syncretism in the Hmong System of Beliefs

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Kao-Ly Yang

2007-01-01

Full Text Available The purpose of this case study is to shed light on the identity of the spirit of fertility called Lady Kaying –Niam Nkauj Kab Yeeb—, its religious origin and the general processes of borrowing her fromother cultures within the Hmong culture. Hmong popular beliefs pertaining to Kaying reveal that Kaying is in fact the Chinese Goddess of Mercy Guanyin. She was imported from MahayanaBuddhism by the Hmong people of China who had retained her roles of the “Bestower of Children", the “Guardian Angel” or the "Conductor of the Dead Children". An analysis of the process of borrowing of the Chinese deity into the Hmong pantheon shows that Lady Kaying overlaps with an ancient spirit, the “Ancestor Spirit of Fertility” or Niam Poj Dab Pog. This case study demonstrates that the processes of borrowing are selective, integrative and comprehensive: some traits or fragments were taken from Buddhism and incorporated into the Hmong beliefs through a superimposing of a Hmong pre-existing system of beliefs.

The impact of MRSA infection in the airways of children with cystic fibrosis; a case-control study.

LENUS (Irish Health Repository)

Cox, D W

2014-01-01

The prevalence of Methicillin Resistant Staphylococcus Aureus (MRSA) in patients with Cystic Fibrosis (CF) has risen dramatically over the past 10 years. The clinical significance of MRSA in CF patients remains undetermined. We conducted a review of patients with CF infected with MRSA over a 10 year period at Our Lady\\'s Children\\'s Hospital, Crumlin between 1999 and 2009. We collected data from 24 patients infected with MRSA and 24 control patients without MRSA There was a significant difference between the two groups in the rate of decline in percentage FEV1 two years after MRSA infection (Difference: -17.4, 95% CI: -30.48, -4.31, p = 0.01). A similar trend was seen for FVC% and FEF25-75% predicted. This study suggests that persistent MRSA infection in the airways of children with CF is associated with diminished lung function two years post acquisition, when compared to a matched control cohort without MRSA.

“The same love, the same faith, the same tears”: ecclesial initiatives about the cult of Our Lady of El Quinche to defend the Republic of the Sacred Heart, Ecuador (1883-1889

Directory of Open Access Journals (Sweden)

Luis Esteban Vizuete Marcillo

2017-07-01

Full Text Available Within the conflict between church and state in the 19th century, the clergy and laymen tried to defend the establishment where the church had hegemony over the state and society. Between 1883 and 1889, Ecuador experienced some ecclesial initiatives to defend which stood for the idea of a Republic of the Sacred Heart. This article studies the case of Our Lady of El Quiche, a colonial massive cult, which was part of a process of re-appropriation and reinterpretation of its history. It also suffered a process of spreading and strengthening of its cult, linking with the image of the Republic, political conflicts and the power of the church. Between politics and religion, the discourses and practices of the clergy and the faithful show the intention of the church to shore up its own idea of a catholic Republic and an organized society. In this article, the use of manuscripts and printed sources give information to contrast multiple voices and multiple religious acts which performed a new local Mariology about El Quinche and a reaction to a context in which the religious hegemony and the participation of the clergy in politics were questioned; meanwhile the relations inside the church were recomposing.

Bone Marrow Transplantation for Leukocyte Adhesion Deficiency-I: Case Report

International Nuclear Information System (INIS)

Al-wahadneh, A.M.; Haddadin, I.; Hamouri, M.; Omari, K.; Ajellat, F.

2006-01-01

Leukocyte Adhesion Deficiency type-I (LAD-I) is a rare autosomal recessive immunodeficiency syndrome leading recurrent bacterial and fungal infections. Bone marrow transplantation offers the only cure. In this report, we describe the course and outcome of bone marrow transplant in a 4-month-old female infant with LAD-I at King Hussein Medical Center, Jordan. A successful matched HLA-I related allogeneic bone marrow transplantation was performed. Engraftment was demonstrated on the 12th day. The patient developed GradeIII grafts versus host disease (GVHD), veno-occlusive disease of the liver and late onset hemorrhagic cystitis. She recovered with appropriate immune reconstitution. (author)

Patients Attitude towards Surgeons Attire in Our Lady of Lourdes Hospital Drogheda

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Babak Meshkat

2015-04-01

Full Text Available Background A doctor’s competence and professionalism is often judged on the basis of attire. Our Lady of Lourdes (OLOL is a leading Irish hospital in the implementation of Bare Below the Elbows (BBTE policy, however surgical attire is not standardised and there is great variability in attire worn on wards. We aimed to evaluate patients attitude towards surgeons attire in OLOL. Methods A prospective survey of adult surgical in-patients was conducted from October 2013 to February 2014. A twelve-question questionnaire was used as data collection tool, using a five point Likert scale to assess patients response to each question. Data were collected on patient demographics, patients level of trust and confidence based on different surgical attire, and patients perception of different attire worn by surgical teams. Results There were 150 completed surveys during the study period with a male to female ratio of 44% to 56% respectively. The mean patient length of in-hospital stay (LOS was 4.7 days (range 1–22. The most commonly represented age group was 30–40 years (18%, with a comparable spread among all age groups. The majority of patients found the attire worn by surgeons on the ward to be very appropriate (93%. Majority of responders believed scrubs to be the most appropriate attire for surgeons on wards (39%, followed by shirt and tie with white coat (38% followed by short sleeved shirt and no tie (18%. Shirt and tie with white coat had a positive effect on patients trust in 63% of responders, a negative effect in 10% and no effect in 26%. Scrubs had a positive effect on patients trust in 63%, negative effect in 11% and no effect in 25%. Short sleeved shirt and no tie had a positive effect in 44%, negative effect in 25% and no effect in 30% of patients. Conclusion Patients in OLOL find attire worn by surgeons to be appropriate. Shirt and tie with white coat or scrubs remains the patient’s choice attire for surgeons. Shirt and tie with white

2001-2011

DEFF Research Database (Denmark)

Poggesi, Anna; Pantoni, Leonardo; Inzitari, Domenico

2011-01-01

they are associated, in cross-sectional surveys, with various disturbances and, in follow-up studies, with poor prognosis. The Leukoaraiosis And DISability (LADIS) study has contributed substantially to this body of knowledge. LADIS is a European multicenter collaboration that was started in 2001 with the aim...... of assessing the independent role of WMC in predicting disability in subjects aged 65-84. The main results of the LADIS study have been released in 2009 with the demonstration that severe WMC more than double the risk of transition from an autonomous to a dependent status after 3 years of follow-up. The LADIS...

A CLINICAL STUDY ON ALLERGIC CONTACT DERMATITIS TO TURMERIC

OpenAIRE

Ashok babu

2013-01-01

ABSTRACT:- BACKGROUND: In south India it is a culture among ladies to use turmeric for beautiful white skin, to remove unwanted hair on the face, in this context I have encountered ladies coming with redness, itching, burning and vesiculation of skin after application of turmeric and also especially on forehead, hair parting after applicat ion of kumkum which is prepared from turmeric and which is traditionally followed by Hindu women. AIM : To evaluate incide...

Lambda-Cyhalothrin Resistance in the Lady Beetle Eriopis connexa (Coleoptera: Coccinellidae) Confers Tolerance to Other Pyrethroids.

Science.gov (United States)

Torres, J B; Rodrigues, A R S; Barros, E M; Santos, D S

2015-02-01

Pyrethroid insecticides are widely recommended to control insect defoliators but lack efficacy against most aphid species. Thus, conserving aphid predators such as the lady beetle Eriopis connexa (Germar) is important to pest management in crop ecosystems that require pyrethroid sprays. In a greenhouse, early fourth-instar larvae and 5-day-old adults from susceptible (S) and resistant (R) E. connexa populations were caged on lambda-cyhalothrin-treated cotton plants, after which survival and egg production (for those caged at adult stage) were assessed. In the laboratory, similar groups were subjected to dried residues and topical treatment with one of eight pyrethroids (alpha-cypermethrin, bifenthrin, deltamethrin, esfenvalerate, fenpropathrin, permethrin, zeta-cypermethrin, and lambda-cyhalothrin), the organophosphate methidathion, or water and wetting agent. After caging on treated cotton terminals, 66% of the R-population larvae survived to adulthood, compared with 2% of those from the S-population. At 12 d after caging at adult stage under the same conditions, 64% of the females from the R-population survived and laid eggs, compared with 100% mortality and no oviposition for the S-females. In trials involving dried insecticide residues, gain in survival based on the survival difference (percentage for R-population minus percentage for S-population) across all tested pyrethroids varied from 3 to 63% for larvae and from 3 to 70% for adults. In trials involving topical sprays of the tested pyrethroids, survival differences ranged from 36 to 96% for larvae and from 21 to 82% for adults. Fenpropathrin and bifenthrin were the least and most toxic, respectively. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Soil-applied imidacloprid translocates to ornamental flowers and reduces survival of adult Coleomegilla maculata, Harmonia axyridis, and Hippodamia convergens lady beetles, and larval Danaus plexippus and Vanessa cardui butterflies.

Science.gov (United States)

Krischik, Vera; Rogers, Mary; Gupta, Garima; Varshney, Aruna

2015-01-01

Integrated Pest Management (IPM) is a decision making process used to manage pests that relies on many tactics, including cultural and biological control, which are practices that conserve beneficial insects and mites, and when needed, the use of conventional insecticides. However, systemic, soil-applied neonicotinoid insecticides are translocated to pollen and nectar of flowers, often for months, and may reduce survival of flower-feeding beneficial insects. Imidacloprid seed-treated crops (0.05 mg AI (active ingredient) /canola seed and 1.2 mg AI/corn seed) translocate less than 10 ppb to pollen and nectar. However, higher rates of soil-applied imidacloprid are used in nurseries and urban landscapes, such as 300 mg AI/10 L (3 gallon) pot and 69 g AI applied to the soil under a 61 (24 in) cm diam. tree. Translocation of imidacloprid from soil (300 mg AI) to flowers of Asclepias curassavica resulted in 6,030 ppb in 1X and 10,400 ppb in 2X treatments, which are similar to imidacloprid residues found in another plant species we studied. A second imidacloprid soil application 7 months later resulted in 21,000 ppb in 1X and 45,000 ppb in 2X treatments. Consequently, greenhouse/nursery use of imidacloprid applied to flowering plants can result in 793 to 1,368 times higher concentration compared to an imidacloprid seed treatment (7.6 ppb pollen in seed- treated canola), where most research has focused. These higher imidacloprid levels caused significant mortality in both 1X and 2X treatments in 3 lady beetle species, Coleomegilla maculata, Harmonia axyridis, and Hippodamia convergens, but not a fourth species, Coccinella septempunctata. Adult survival were not reduced for monarch, Danaus plexippus and painted lady, Vanessa cardui, butterflies, but larval survival was significantly reduced. The use of the neonicotinoid imidacloprid at greenhouse/nursery rates reduced survival of beneficial insects feeding on pollen and nectar and is incompatible with the principles of IPM.

Soil-applied imidacloprid translocates to ornamental flowers and reduces survival of adult Coleomegilla maculata, Harmonia axyridis, and Hippodamia convergens lady beetles, and larval Danaus plexippus and Vanessa cardui butterflies.

Directory of Open Access Journals (Sweden)

Vera Krischik

Full Text Available Integrated Pest Management (IPM is a decision making process used to manage pests that relies on many tactics, including cultural and biological control, which are practices that conserve beneficial insects and mites, and when needed, the use of conventional insecticides. However, systemic, soil-applied neonicotinoid insecticides are translocated to pollen and nectar of flowers, often for months, and may reduce survival of flower-feeding beneficial insects. Imidacloprid seed-treated crops (0.05 mg AI (active ingredient /canola seed and 1.2 mg AI/corn seed translocate less than 10 ppb to pollen and nectar. However, higher rates of soil-applied imidacloprid are used in nurseries and urban landscapes, such as 300 mg AI/10 L (3 gallon pot and 69 g AI applied to the soil under a 61 (24 in cm diam. tree. Translocation of imidacloprid from soil (300 mg AI to flowers of Asclepias curassavica resulted in 6,030 ppb in 1X and 10,400 ppb in 2X treatments, which are similar to imidacloprid residues found in another plant species we studied. A second imidacloprid soil application 7 months later resulted in 21,000 ppb in 1X and 45,000 ppb in 2X treatments. Consequently, greenhouse/nursery use of imidacloprid applied to flowering plants can result in 793 to 1,368 times higher concentration compared to an imidacloprid seed treatment (7.6 ppb pollen in seed- treated canola, where most research has focused. These higher imidacloprid levels caused significant mortality in both 1X and 2X treatments in 3 lady beetle species, Coleomegilla maculata, Harmonia axyridis, and Hippodamia convergens, but not a fourth species, Coccinella septempunctata. Adult survival were not reduced for monarch, Danaus plexippus and painted lady, Vanessa cardui, butterflies, but larval survival was significantly reduced. The use of the neonicotinoid imidacloprid at greenhouse/nursery rates reduced survival of beneficial insects feeding on pollen and nectar and is incompatible with the

Soil-Applied Imidacloprid Translocates to Ornamental Flowers and Reduces Survival of Adult Coleomegilla maculata, Harmonia axyridis, and Hippodamia convergens Lady Beetles, and Larval Danaus plexippus and Vanessa cardui Butterflies

Science.gov (United States)

Krischik, Vera; Rogers, Mary; Gupta, Garima; Varshney, Aruna

2015-01-01

Integrated Pest Management (IPM) is a decision making process used to manage pests that relies on many tactics, including cultural and biological control, which are practices that conserve beneficial insects and mites, and when needed, the use of conventional insecticides. However, systemic, soil-applied neonicotinoid insecticides are translocated to pollen and nectar of flowers, often for months, and may reduce survival of flower-feeding beneficial insects. Imidacloprid seed-treated crops (0.05 mg AI (active ingredient) /canola seed and 1.2 mg AI/corn seed) translocate less than 10 ppb to pollen and nectar. However, higher rates of soil-applied imidacloprid are used in nurseries and urban landscapes, such as 300 mg AI/10 L (3 gallon) pot and 69 g AI applied to the soil under a 61 (24 in) cm diam. tree. Translocation of imidacloprid from soil (300 mg AI) to flowers of Asclepias curassavica resulted in 6,030 ppb in 1X and 10,400 ppb in 2X treatments, which are similar to imidacloprid residues found in another plant species we studied. A second imidacloprid soil application 7 months later resulted in 21,000 ppb in 1X and 45,000 ppb in 2X treatments. Consequently, greenhouse/nursery use of imidacloprid applied to flowering plants can result in 793 to 1,368 times higher concentration compared to an imidacloprid seed treatment (7.6 ppb pollen in seed- treated canola), where most research has focused. These higher imidacloprid levels caused significant mortality in both 1X and 2X treatments in 3 lady beetle species, Coleomegilla maculata, Harmonia axyridis, and Hippodamia convergens, but not a fourth species, Coccinella septempunctata. Adult survival were not reduced for monarch, Danaus plexippus and painted lady, Vanessa cardui, butterflies, but larval survival was significantly reduced. The use of the neonicotinoid imidacloprid at greenhouse/nursery rates reduced survival of beneficial insects feeding on pollen and nectar and is incompatible with the principles of IPM

The Study on the Thyroid Disease

International Nuclear Information System (INIS)

Lee, Mun Ho

1982-01-01

Several recent advances in our knowledge of thyroid physiology have broad application to the diagnosis and management of thyroid disorders. For in the thyroid, more than other end-ocrine organs, pathophysiology can be translated directly into the diagnosis and management of thyroid disease. Graves' disease is a syndrome including goiter with hyperthyroidism, exophthalmos and dermatopathy. The pathogenesis of Graves' disease is not yet clearly identified, but various autoantibodies to the thyroid gland and immunapathalogic studied indicate that autoimmune processes are involved in the pathogenesis of the disease. The diagnosis and management of Graves' disease are largely dependent on radionuclide technique as radioimmunoassay, radioactive iodine therapy and so on. Several laboratory tests are also developed to determine the remission of this disease including TRH stimulation test, T 3 , suppression test and detection of thyroid stimulating immunoglobulins. Autoimmune thyroiditis is almost certainly a primary immunologic disease and the incidence tends to increase recently, mainly due to the application of biopsy technique is thyroid diseases. Thyroid nodules have been a great challenge to physicians because of the possibility of malignancy. But recently, cytologic examination of thyroid aspirate provides a very simple and also reliable diagnostic method in patients with thyroid nodules. In 163 patients with thyroid nodules, only 19.3% was revealed to be malignant. Therefore cytologic examination of thyroid aspirate and thyroid biopsy should be included in the diagnosis of nodular patients prior to surgical intervention. In this paper, a comprehensive review is presented on the pathogenesis, clinical features, laboratory findings and therapeutic modalities of various thyroid diseases on the basis of over 80 researches performed during the past 20 years at radioisotope clinic, Seoul National University Hospital.

A controlled experiment on the impact of software structure on maintainability

Science.gov (United States)

Rombach, Dieter H.

1987-01-01

The impact of software structure on maintainability aspects including comprehensibility, locality, modifiability, and reusability in a distributed system environment is studied in a controlled maintenance experiment involving six medium-size distributed software systems implemented in LADY (language for distributed systems) and six in an extended version of sequential PASCAL. For all maintenance aspects except reusability, the results were quantitatively given in terms of complexity metrics which could be automated. The results showed LADY to be better suited to the development of maintainable software than the extension of sequential PASCAL. The strong typing combined with high parametrization of units is suggested to improve the reusability of units in LADY.

Visual effects of the first ladies’ Kebaya clothing on the image of Indonesian women’s appearances

Science.gov (United States)

Suciati

2016-04-01

The image of Indonesian women on international level is partly influenced by the appearance of the First Lady. The role and position of the First Lady is the representation of Indonesian women, because basically the First Lady, as the wife who accompanies the President (head of state), has a strong background of cultural grip, high intellectuality and good personality in her daily lifestyle, including in wearing clothes, and as an ambassador of culture and design. Fashion style of the First Lady always draws praise and criticism from the public. The purpose of this study is to reveal the visualization effects of Indonesian First Ladies’ kebaya clothing style in various state occasions on the image of Indonesian women’s appearances. This study is a qualitative research of visual data that emphasizes the discussion of Kebaya Clothing using semiological study (connotation and denotation meaning) that bring out self-image. The results showed that the style the First Ladies’ Kebaya clothing in every presidency period of their husbands had characteristics both in the style of clothing or hairstyle, indicating self-image. The conclusion of this study reveals that the First Ladies’ Kebaya Clothing (National Clothing) is interpreted as having implied messages because clothing can be observed visually. Implication was done on the construction of learning patterns of clothing, national fashion design and Nusantara ethnic clothing design.

“Knaller-Sex für alle”: Popfeminist Body Politics in Lady Bitch Ray, Charlotte Roche, and Sarah Kuttner

Directory of Open Access Journals (Sweden)

Carrie Smith-Prei

2011-01-01

Full Text Available Germany has seen a recent upsurge in publications proclaiming that feminism is again an urgent matter for a new generation of women. Faced with the reactionary demography debate and the hegemony of second-wave feminism, young writers, musicians, journalists, and critics call for new models of feminism relevant to women today. As one of these viable models, popfeminism draws on dominant trends in mass culture, on pop’s forty-year history as a cultural prefix in Germany, and on traditional feminism in order to create a new, ostensibly apolitical, feminist subculture based in self-stylization and individual autonomy. Shared by many popfeminist sources is the depiction of negatively coded female corporeality. This article begins with a theoretical analysis of writings on sexuality and the body in recent (popfeminist nonfiction. It then examines the negative corporeal self-stylizations in Turkish-German rapper Lady Bitch Ray’s performances since 2006, in former music video host Charlotte Roche’s novel Feuchtgebiete (2008, and in media personality Sarah Kuttner’s novel Mängelexemplar (2009. Ultimately, these negatively coded bodies are shown to uncover popfeminism’s political intent.

Mother-Offspring Relations: Prey Quality and Maternal Size Affect Egg Size of an Acariphagous Lady Beetle in Culture

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Eric W. Riddick

2012-01-01

Full Text Available We investigated mother-offspring relations in a lady beetle Stethorus punctillum Weise that utilizes spider mites as prey. Our objectives were to determine if (1 prey quality affects egg size, (2 maternal size correlates with egg size, and (3 egg size affects hatching success. We fed predators spider mites Tetranychus urticae Koch from lima bean Phaseolus lunatus L. foliage in the laboratory. Mothers of unknown body size offered high rather than low quality spider mites since birth produced larger eggs. Mothers of known body size offered only high quality spider mites, produced eggs of variable size, but mean egg size correlated positively with hind femur length. Mothers laid their eggs singly, rather than in batches, and eggs were large relative to femur size. Egg size did not affect hatch success; mean hatch rate exceeded 95% regardless of egg size. In conclusion, the quality of prey consumed by S. punctillum mothers while in the larval stage can affect their size as adults and, consequently, the size of their eggs. The behavior of laying eggs singly, the positive relationship between maternal size and mean egg size, and the high rate of egg hatch suggest that S. punctillum mothers invest heavily in offspring.

Efeito da aplicação de ácido giberélico no crescimento da palmeira-ráfia Effect of gibbeerllic acid application on lady palm growth

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Armando Reis Tavares

2007-12-01

Full Text Available A palmeira-ráfia possui grande importância econômica devido ao seu interesse comercial. É uma planta ornamental muito apreciada por sua beleza e utilização em ambiente interno, crescendo bem em locais com sombra e apresentando resistência à exposição solar. O valor econômico dessa planta está relacionado à altura e número de hastes. O objetivo do trabalho foi promover o crescimento da planta, através da aplicação do regulador de crescimento ácido giberélico (GA3. Mudas de palmeira-ráfia com aproximadamente um ano de idade foram aspergidas a cada 21 dias (quatro aplicações com solução de ácido giberélico nas concentrações de 0; 75; 150; 225; e 300 mg.L-1. Os resultados indicaram que a aplicação do ácido giberélico foi eficiente na promoção do crescimento da espécie, sendo esse incremento significativo nas variáveis: comprimento dos pecíolos, lâminas foliares e altura da planta. Não se observou diferença no acúmulo de matéria seca ou fresca do pecíolo entre os tratamentos, e plantas do tratamento-controle foram superiores às dos tratamentos 225 e 300 mg L-1, nas variáveis diâmetro do colo e massa fresca e seca das raízes. Devido ao incremento na altura das mudas e à alteração da disposição das folhas da palmeira, a utilização do ácido giberélico pode ser recomendada para a produção de mudas de alta qualidade.Lady Palm is of great economic importance due its commercial interest. It is an ornamental plant growing in shadowy places, resistant to sun exposure and very appreciated for its beauty and ornamental value. Its commercial value is associated to plant height and shoot number. The aim of this work was to stimulate lady palm growth by applying the plant growth regulator gibberellic acid. Plantlets of R. excelsa approximately one year old were sprayed every 21 days (4 applications with gibberellic acid solution at concentrations of 0; 75; 150; 225 and 300 mg L-1. The results showed that

Balancing Act: A Study of International School Heads' Efforts to Manage the Professional and Personal Aspects of Their Lives

Science.gov (United States)

Sorenson, Christiane PJ

2010-01-01

Interest in the topic of professional and personal life balance has increased exponentially over the past several decades. The topic even is listed by the current First Lady of the United States as a priority item to be addressed during her husband's first four years in office. While studies have been conducted about the professional/personal…

Necrotizing lymphadenitis: If not tuberculosis then what?

Science.gov (United States)

Punjabi, Rhea K

2018-01-01

We present a rare case of Kikuchi disease in a young lady presenting with fever and cervical lymphadenopathy. Clinically, the disease mimics tuberculosis and lymphoma. Lymph node biopsy is diagnostic and treatment is symptomatic. Although tuberculosis is endemic, clinicians should be aware of uncommon conditions as early recognition of the disease will minimize unnecessary evaluation and treatment.

A cross-sectional survey to study the relationship of periodontal disease with cardiovascular disease, respiratory disease, and diabetes mellitus.

Science.gov (United States)

Oberoi, Sukhvinder Singh; Harish, Yashoda; Hiremath, Shivalingaswamy; Puranik, Manjunath

2016-01-01

Periodontal deterioration has been reported to be associated with systemic diseases such as cardiovascular disease (CVD), diabetes mellitus, respiratory disease, liver cirrhosis, bacterial pneumonia, nutritional deficiencies, and adverse pregnancy outcomes. The present study assessed the periodontal disease among patients with systemic conditions such as diabetes, CVD, and respiratory disease. The study population consisted of 220 patients each of CVD, respiratory disease, and diabetes mellitus, making a total of 660 patients in the systemic disease group. A control group of 340 subjects were also included in the study for comparison purpose. The periodontal status of the patients with these confirmed medical conditions was assessed using the community periodontal index of treatment needs (CPITNs) index. The prevalence of CPITN code 4 was found to be greater among the patients with respiratory disease whereas the mean number of sextants with score 4 was found to be greater among the patients with diabetes mellitus and CVD. The treatment need 0 was found to be more among the controls (1.18%) whereas the treatment need 1, 2, and 3 were more among the patients with respiratory disease (100%, 97.73%, and 54.8%), diabetes mellitus (100%, 100% and 46.4%), and CVD (100%, 97.73%, and 38.1%), in comparison to the controls (6.18%). From the findings of the present study, it can be concluded that diabetes mellitus, CVD, and respiratory disease are associated with a higher severity of periodontal disease.

A cross-sectional survey to study the relationship of periodontal disease with cardiovascular disease, respiratory disease, and diabetes mellitus

Directory of Open Access Journals (Sweden)

Sukhvinder Singh Oberoi

2016-01-01

Full Text Available Background: Periodontal deterioration has been reported to be associated with systemic diseases such as cardiovascular disease (CVD, diabetes mellitus, respiratory disease, liver cirrhosis, bacterial pneumonia, nutritional deficiencies, and adverse pregnancy outcomes. Aim: The present study assessed the periodontal disease among patients with systemic conditions such as diabetes, CVD, and respiratory disease. Materials and Methods: The study population consisted of 220 patients each of CVD, respiratory disease, and diabetes mellitus, making a total of 660 patients in the systemic disease group. A control group of 340 subjects were also included in the study for comparison purpose. The periodontal status of the patients with these confirmed medical conditions was assessed using the community periodontal index of treatment needs (CPITNs index. Results: The prevalence of CPITN code 4 was found to be greater among the patients with respiratory disease whereas the mean number of sextants with score 4 was found to be greater among the patients with diabetes mellitus and CVD. The treatment need 0 was found to be more among the controls (1.18% whereas the treatment need 1, 2, and 3 were more among the patients with respiratory disease (100%, 97.73%, and 54.8%, diabetes mellitus (100%, 100% and 46.4%, and CVD (100%, 97.73%, and 38.1%, in comparison to the controls (6.18%. Conclusion: From the findings of the present study, it can be concluded that diabetes mellitus, CVD, and respiratory disease are associated with a higher severity of periodontal disease.

The Ancestors’ Legend

Institute of Scientific and Technical Information of China (English)

1999-01-01

The Fairy Lady of Wushan Mountain Yao Ji, youngest daughter of Emperor Yandi, sent to thesouth of Wushan Mountain in the Three Gorges, was named theFairy Lady of Wushan Mountain. When King Chu Huaiwangwas on a tour to Gaotang. he dreamed of the fair lady. Later,when King Chu Xiangwang was on the same tour, he too mether in a dream. Yao Ji grew a majestic plant, plucked it andmade it an iris. It was said that if stewed and eaten, the one whoate may chance to meet their lover in their dreams.

A case of simultaneous occurrence of Graves′ disease and Hashimoto′s thyroiditis

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Anirban Majumder

2012-01-01

Full Text Available Introduction: Simultaneous occurrence of Hashimoto′s thyroiditis (HT, and Graves′ disease (GD is rare. Aims and Objectives: We report a case of simultaneous occurrence of GD and HD, at presentation. Case Report: A 60-year-old lady presented with tremulousness of hands, palpitation, and excessive sweating. She had a history of weight loss and neck-swelling. Her weight was 46 kg, BMI 17, afebrile, regular pulse rate of 110/min with fine tremor in hands. Thyroid gland was symmetrically enlarged, firm, without any bruit, but mildly tender with lobular surface. There were no occular manifestations. Initial thyroid function tests (TFT revealed: T3: 3.80 ng/ml (0.80-2.10, T4: 12.40 ug/dl (5.10-12, thyroid stimulating hormone (TSH: 0.20 μU/L (0.70-5. Her anti thyroperoxidase (TPO antibody: 374 IU/ml (normal [nl.] <35 and TSH receptor antibody: 15 U/L (nl. <1 were both strongly positive. Ultrasonogram of thyroid revealed a hypoechoic enlarged gland. 99mTc pertechnetate scan showed an enlarged gland with increased uptake of radiocontrast: 17% (nl. 0.4-4% with some patchy defects in both lower poles. Thyroid fine needle aspiration cytology (FNAC showed sheets of Hurthle cells with abdunce of lymphocytes indicating HT. She was observed on beta blockers. Repeat TFT, 3 months later showed: T3: 4.20 ng/ml, T4: 14.40 ug/dl, TSH: 0.001 μU/L, with increased uptake on repeat scan. Conclusion: HT rarely occurs following GD. Our case of an elderly lady with no eye signs, lobular, firm tender goiter with patchy uptake in both lower poles on Tc99m scan were odd points in diagnosing isolated GD. FNAC confirmed simultaneous HD with GD.

Necrotizing lymphadenitis: If not tuberculosis then what?

Directory of Open Access Journals (Sweden)

Rhea K Punjabi

2018-01-01

Full Text Available We present a rare case of Kikuchi disease in a young lady presenting with fever and cervical lymphadenopathy. Clinically, the disease mimics tuberculosis and lymphoma. Lymph node biopsy is diagnostic and treatment is symptomatic. Although tuberculosis is endemic, clinicians should be aware of uncommon conditions as early recognition of the disease will minimize unnecessary evaluation and treatment.

A preliminary neutron crystallographic study of thaumatin

Energy Technology Data Exchange (ETDEWEB)

Teixeira, Susana C. M. [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); Blakeley, Matthew P. [Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); Leal, Ricardo M. F. [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); ESRF, 6 Rue Jules Horowitz, BP-220, 38043 Grenoble (France); Mitchell, Edward P. [EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom); ESRF, 6 Rue Jules Horowitz, BP-220, 38043 Grenoble (France); Forsyth, V. Trevor, E-mail: tforsyth@ill.fr [ILL-EMBL Deuteration Laboratory, Partnership for Structural Biology, 6 Rue Jules Horowitz, 38042 Grenoble (France); Institut Laue Langevin, 6 Rue Jules Horowitz, 38042 Grenoble (France); EPSAM and ISTM, Keele University, Staffordshire ST5 5BG (United Kingdom)

2008-05-01

Preliminary neutron crystallographic data from the sweet protein thaumatin have been recorded using the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results illustrate the feasibility of a full neutron structural analysis aimed at further understanding the molecular basis of the perception of sweet taste. Such an analysis will exploit the use of perdeuterated thaumatin. A preliminary neutron crystallographic study of the sweet protein thaumatin is presented. Large hydrogenated crystals were prepared in deuterated crystallization buffer using the gel-acupuncture method. Data were collected to a resolution of 2 Å on the LADI-III diffractometer at the Institut Laue Langevin (ILL). The results demonstrate the feasibility of a full neutron crystallographic analysis of this structure aimed at providing relevant information on the location of H atoms, the distribution of charge on the protein surface and localized water in the structure. This information will be of interest for understanding the specificity of thaumatin–receptor interactions and will contribute to further understanding of the molecular mechanisms underlying the perception of taste.

Bosom Friends and the Sapphic Breasts of Belinda

OpenAIRE

Ula E. Klein

2013-01-01

This article examines Maria Edgeworth’s 1801 novel Belinda in order to argue that the breast at the center of Lady Delacour’s narrative signifies not maternal failure but Sapphic feelings and connections. While previous studies of the novel have discussed the wounded breast of Lady Delacour as a punishment for her transgressions or as an emblem of her patriarchal oppression, this article claims that the wounded breast is both a sign of and a means to female same-sex desire and relationships. ...

Environmental Impact Study of the Northern Section of the Upper Mississippi River. Pool 1.

Science.gov (United States)

1973-11-01

grass P Poa pratensis Blue grass Setaria viridis Green foxtail P P P P D Setaria sp. Bristly foxtail P Spartina pectinata Prairie cord grass P...Agrimonia pubescens Cocklebur Alchemilla sp. Lady’s mantle P Fragaria vesca Wild strawberry Oewn canadense White avens Gewn laciniatun Avens Geum

The oral-systemic disease connection: a retrospective study.

Science.gov (United States)

Joseph, Bobby K; Kullman, Leif; Sharma, Prem N

2016-11-01

The study aimed at determining the association between oral disease and systemic health based on panoramic radiographs and general health of patients treated at Kuwait University Dental Center. The objective was to determine whether individuals exhibiting good oral health have lower propensity to systemic diseases. A total of 1000 adult patients treated at Kuwait University Dental Center were randomly selected from the patient's records. The general health of patients was assessed from the medical history of each patient recorded during their visit to the clinic. The number of reported diseases and serious symptoms were used to develop a medical index. The oral health of these patients was assessed from panoramic radiographs to create an oral index by evaluating such parameters as caries, periodontitis, periapical lesions, pericoronitis, and tooth loss. In a total of 887 patients, 43.8 % had an oral index between 3 and 8, of which significantly higher (62.1 %) patients were with medical conditions compared to those without (33.2 %; p relationship when the diagnosis of oral disease was based primarily on radiographic findings. Future research needs to include prospective clinical and interventional studies. The significance of the oral-systemic disease connection highlights the importance of preventing and treating oral disease which have profound medical implications on general health.

Cognitive stereotypes, forming the concept “business lady” in naïve world picture (on the material of Russian and German languages

Directory of Open Access Journals (Sweden)

Badanyan Irina Felixovna

2016-06-01

Full Text Available On the material of modern media texts in Russian and German it is described linguacultural specificity of the concept “business lady” through the cognitive system of stereotypes, reflecting the typical notions of modern business lady in the naive picture of the world. The practical material for the article was the text information, analytical and business publications, published in the print or electronic media in Russian and German. The study implied the methods of frame modeling and contextual analysis. It is identified cognitive layers of the concept, investigated the specificity of its lexical and semantic representations. On the basis of the selected cognitive signs frame structure “business lady” is considered as a set of slots that objectifies the typical signs of a business lady, typical of Russian and German world pictures. It was found that the stereotypical image of a business lady has a certain set of features – professional and moral qualities, intellectual ability, education, behavior, appearance, age, etc. Thus the formation of a business lady’s image in media texts takes place in close connection with the formation of stereotypes about women in the field of business relations, i.e. relying on certain standardized representation of business lady, which are fixed in the public mind.

Environmental Impact Study of the Northern Section of the Upper Mississippi River. Pool 2.

Science.gov (United States)

1973-11-01

Setaria viridis Green foxtail P P P P D Setaria sp. Bristly foxtail P Spartina pectinata Prairie cord grass P Unidentified sp. D P P 1YDROCHARITACEAE...americanus New Jersey tea ROSACEAE Agrimonia pubescens Cocklebur Alchemilla sp. Lady’s mantle P Fragaria oesca Wild strawberry Cewn canadense White avens

Location of lacunar infarcts correlates with cognition in a sample of non-disabled subjects with age-related white-matter changes: the LADIS study

DEFF Research Database (Denmark)

Benisty, S; Gouw, A A; Porcher, R

2009-01-01

evaluation was based on the Mini Mental Status Examination (MMSE), a modified Alzheimer Diseases Assessment Scale for global cognitive functions, and compound Z scores for memory, executive functions, speed and motor control. WMH were rated according to the Fazekas scale; the number of lacunes was assessed...... a significant negative association between the presence of lacunes in putamen/pallidum and the memory compound Z score (beta = -0.13; p = 0.038). By contrast, no significant negative association was found between cognitive parameters and the presence of lacunes in internal capsule, lobar white matter......OBJECTIVES: In cerebral small vessel disease, white-matter hyperintensities (WMH) and lacunes are both related to cognition. Still, their respective contribution in older people remains unclear. The purpose of this study is to assess the topographic distribution of lacunes and determine whether...

Study on the correlation between the trace elements with cerebrovascular diseases

Energy Technology Data Exchange (ETDEWEB)

Dazhong, Zhang; Mingsong, Tai; Suqing, Chen [Sichuan Univ., Chengdu, SC (China). Inst. of Nuclear Science and Technology; and others

1990-11-01

In the paper, the correlation between the cerebroscular diseases, as haemorrhage, cerebral atherosclerosis, cerebral embolism, with trace element contents in hair and tissues of controls and diseases has been studied by PIXE. Biochemistry test for diseased cerebral atheroselerosis patientes were done. The distinction between the controls and diseases were revealed.

The Ladies' Diary

Indian Academy of Sciences (India)

IAS Admin

supposing that for every time the first hand moves round, the second hand goes 10 times, ... derive the sidereal day, the synodic periods of moon and planets. Quite interestingly this has .... The daring artist took his flight,. Soaring beyond frail ...

Determination of trace elements of Egyptian crops by neutron activation analysis. Pt. 3. Trace elements in African tea, ginger, canella bark, black pepper, sesame, lady's fingers, jew's mallow, tomatos, cucumber and marrow

Energy Technology Data Exchange (ETDEWEB)

Sherif, M K; Awadallah, R M; Amrallah, A H [Assiut Univ. (Egypt)

1980-01-01

Multielemental neutron activation analysis was used for the determination of Al, As, Au, Br, Ca, Cd, Co, Cr, Cu, Fe, La, Mn, Mo, Sb, Se, W and Zn in African tea and lady's fingers (Malvaceae Family), ginger (Zingiperanceae Family), canella bark (Laureceae Family), black pepper (Piperaceae Family), cucumber seeds and vegetable marrow seeds (Cucurbitaceae Family), tomatos seed (Solanaceae Family), safflower seeds (Compositae Family), jew's mallow seed (Tiliaceae Family) and sesame (Pedaliaceae Family). Trace elements determination was made for the analysis of destructive (using super pure nitric acid and adsorbing the metal-APDC and metal-Dz complexes on activated charcoal) and nondestructive (dry seeds) samples. The method is simple, precise and sensitive for the determination of microamounts of the elements (ppM to ppB).

Environmental Impact Study of The Northern Section of the Upper Mississippi River, Minnesota River Pool.

Science.gov (United States)

1973-11-01

Setaria viridis I Green foxtail P P P P D Setaria sp. I Bristly foxtail P Spartina pectinata Prairie cord grass P Unidentified sp. D P P...Thalictrn sp. Meadow-rue P P RPAMNACEAE Ceanothus omericanus New Jersey tea ROSACEAE Agrimonia pubescens Cocklebur AZchemilla sp. Lady’s mantle P Fragaria

A study on periodontal disease and systemic disease relationship a hospital based study in Bangalore

Directory of Open Access Journals (Sweden)

Sukhvinder Singh Oberoi

2013-01-01

Full Text Available Background: Periodontal deterioration has been reported to be associated with various systemic conditions like Cardiovascular disease, Diabetes, Respiratory disease, Liver cirrhosis, Bacterial Pneumonia, Nutritional deficiencies and adverse pregnancy outcomes. Aim: To assess the periodontal disease among patients with systemic disease/conditions. Materials and Method: A total of 500 patients with systemic disease/conditions (Diabetes, Cardiovascular disease, Respiratory disease and Renal disease and 500-age and gender matched controls without systemic disease/conditions were selected from the Government Hospitals in Bangalore City. The medical conditions were recorded and the periodontal status of the study population was assessed using the CPITN index. Results: The prevalence of CPITN Code 4 was found to be more among the patients with systemic disease/conditions (46.2%. The mean number of sextants with CPITN code 3 and 4 were more among the patients with systemic disease/conditions. The prevalence of CPITN code was found to be more among the patients with Respiratory disease whereas the mean number of sextants was found to be more among the patients with Diabetes, Cardiovascular and Renal disease. Conclusion: It may be concluded that the systemic diseases/conditions are associated with higher severity of periodontal disease.

The scientist lady

Indian Academy of Sciences (India)

Lawrence

stream of her life also must have been quiet, easy, un- eventful. It was not so, she ... That too when she had full support from her family. Little Kamala ... doing research work at that famous institute was a matter of course. She then applied for ... work would not be recognized until the director was satisfied about its quality and.

A large pericardial effusion and bilateral pleural effusions as the initial manifestations of Familial Mediterranean Fever

OpenAIRE

Schembri, Emma Louise; Mifsud, Simon; Cassar Demarco, Daniela; Coleiro, Bernard; Mallia, Carmel

2015-01-01

Familial Mediterranean Fever (FMF) is a condition characterized by recurrent febrile poly-serositis. Typical presentations of the disease include episodes of fever, abdominal pain and joint pains. Chest pain is a less common presentation. We report a case of FMF which presented with a large pericardial effusion and bilateral pleural effusions in a lady who had no positive family history and negative genetic testing.

Bosom Friends and the Sapphic Breasts of Belinda

Directory of Open Access Journals (Sweden)

Ula E. Klein

2013-11-01

Full Text Available This article examines Maria Edgeworth’s 1801 novel Belinda in order to argue that the breast at the center of Lady Delacour’s narrative signifies not maternal failure but Sapphic feelings and connections. While previous studies of the novel have discussed the wounded breast of Lady Delacour as a punishment for her transgressions or as an emblem of her patriarchal oppression, this article claims that the wounded breast is both a sign of and a means to female same-sex desire and relationships. This article contrasts the wounded, festering breast with the tableau that ends the novel. The tableau, a constructed vision of social expectations at the time, is undermined by Lady Delacour’s final couplet that encourages the reader to “find the moral” of the story. The wounded breast and the many ways in which it connects the characters of Lady Delacour, Belinda and Mrs. Freke undermine the heteronormative tableau that ends the novel and complicate the suggestion that the moral of the story is easy to understand. By exploring the ways in which the breast functions to connect these women through its wounding and its cure, I argue that Sapphic possibilities arise throughout the novel. These possibilities suggest the centrality of the female same-sex relationships to the novel over the heterosexual ones that figure in the tableau.

Molecular Genetic Studies of Some Eye Diseases Affecting the ...

Indian Academy of Sciences (India)

First page Back Continue Last page Overview Graphics. Molecular Genetic Studies of Some Eye Diseases Affecting the Indian Population. Single gene disorders. Complex eye diseases. Genotype-phenotype correlation. Molecular diagnostics.

Samaru Journal of Information Studies -main-fx

African Journals Online (AJOL)

USER

experiences paid off by making her famous and recognized by the lady with .... According to American Library Association (ALA. 1980), special .... video films for their students to enhance their creativity ..... Agrees of South-East-Asian. Librarian.

Nutritional status and eating disorders: neglected risks factor for nontuberculous mycobacterial lung disease?

Science.gov (United States)

Portillo, Karina; Morera, Josep

2012-01-01

Nontuberculous mycobacterial lung disease (NTMLD) in immunocompetent patients is an increasingly important epidemiologic concern. However, risk factors associated with susceptibility to NTMLD are not completely known. A prevalence of NTMLD appears to be rising, mainly in some populations such as middle-aged or elderly thin women, (a group including those with Lady Windermere syndrome) with neither remarkable history of respiratory disease nor smoking habit. Right middle lobe (RML) and lingula are often involved. Various predisposing factors and genetic defects have been described as possible causes of development of NTMLD, namely: voluntary suppression of cough, RML anatomical factors, menopause and mutations in cystic fibrosis transmembrane conductance regulator (CFTR). Malnutrition is also an important and common risk factor associated with other mycobacterial disease like tuberculosis (TB) and its probable association with NTMLD as have been pointed out for some authors. However, a real description of all nutritional aspects and eating habits of patients prior to NTMLD diagnosis is lacking. We hypothesized that malnutrition and eating disorders like anorexia nervosa could be risk factors that may promoting NTMLD. From a clinical viewpoint, if this hypothesis proves to be correct, eating habits and nutritional aspects should be taken into account in the diagnosis process of suspected NTMLD, since they are easily identifiable and treatable conditions. Copyright © 2011 Elsevier Ltd. All rights reserved.

Primary splenic lymphoma

International Nuclear Information System (INIS)

Aslam, M.; Salamat, N.; Mamoon, N.; Ahmed, M.

2006-01-01

A middle-aged lady presented with fever and splenomegaly and had been provisionally treated for malaria, typhoid and tuberculosis. Diagnostic splenectomy was performed which revealed diffuse large cell lymphoma, B type, localized to spleen. Patient had remission of disease after splenectomy. (author)

Primary splenic lymphoma

Energy Technology Data Exchange (ETDEWEB)

Aslam, M [Combined Military Hospital, Multan (Pakistan). Dept. of Surgery; Salamat, N [Combined Military Hospital, Multan (Pakistan). Dept. of Pathology; Mamoon, N [Armed Forces Inst. of Pathology, Rawalpindi (Pakistan). Dept. of Histopathology; Ahmed, M [Combined Military Hospital, Multan (Pakistan). Dept. of Medicine

2006-04-15

A middle-aged lady presented with fever and splenomegaly and had been provisionally treated for malaria, typhoid and tuberculosis. Diagnostic splenectomy was performed which revealed diffuse large cell lymphoma, B type, localized to spleen. Patient had remission of disease after splenectomy. (author)

Abelmoschus esculentus

African Journals Online (AJOL)

Pedro

2015-02-16

Feb 16, 2015 ... Author(s) agree that this article remains permanently open access under the terms of the Creative Commons .... assumptions of parametric tests and obtain consistent results, the .... Ladies Finger (Abelmoschus esculentus L.) in Mice. Sci. ... and okra mosaic viral diseases, under field conditions in South.

Longitudinal Andhra Pradesh Eye Disease Study: rationale, study design and research methodology.

Science.gov (United States)

Khanna, Rohit C; Murthy, Gudlavalleti Vs; Marmamula, Srinivas; Mettla, Asha Latha; Giridhar, Pyda; Banerjee, Seema; Shekhar, Konegari; Chakrabarti, Subhabrata; Gilbert, Clare; Rao, Gullapalli N

2016-03-01

The rationale, objectives, study design and procedures for the longitudinal Andhra Pradesh Eye Disease Study are described. A longitudinal cohort study was carried out. Participants include surviving cohort from the rural component of Andhra Pradesh Eye Disease Study. During 1996-2000, Andhra Pradesh Eye Disease Survey was conducted in three rural (n = 7771) and one urban (n = 2522) areas (now called Andhra Pradesh Eye Disease Study 1). In 2009-2010, a feasibility exercise (Andhra Pradesh Eye Disease Study 2) for a longitudinal study (Andhra Pradesh Eye Disease Study 3) was undertaken in the rural clusters only, as urban clusters no longer existed. In Andhra Pradesh Eye Disease Study 3, a detailed interview will be carried out to collect data on sociodemographic factors, ocular and systemic history, risk factors, visual function, knowledge of eye diseases and barriers to accessing services. All participants will also undergo a comprehensive eye examination including photography of lens, optic disc and retina, Optic Coherence Tomography of the posterior segment, anthropometry, blood pressure and frailty measures. Measures include estimates of the incidence of visual impairment and age-related eye disease (lens opacities, glaucoma and age-related macular degeneration) and the progression of eye disease (lens opacities and myopia) and associated risk factors. Of the 7771 respondents examined in rural areas in Andhra Pradesh Eye Disease Study 1, 5447 (70.1%) participants were traced in Andhra Pradesh Eye Disease Study 2. These participants will be re-examined. Andhra Pradesh Eye Disease Study 3 will provide data on the incidence and progression of visual impairment and major eye diseases and their associated risk factors in India. The study will provide further evidence to aid planning eye care services. © 2015 Royal Australian and New Zealand College of Ophthalmologists.

Rheumatic disease in a Nigerian lady with sarcoidosis: Case report ...

African Journals Online (AJOL)

She had multiple joint pains, fever, oral ulcers and weight loss with associated anorexia. She developed significant hair loss, fatigue, redness of the eyes; with poor vision, and hearing impairment of about 6 years duration at the time of presentation. Essential findings were those of hearing impairment and a few crepitations ...

Parkinson's disease prevalence in Fabry disease: A survey study

Directory of Open Access Journals (Sweden)

Adina H. Wise

2018-03-01

Full Text Available Recent research has suggested a possible link between Parkinson's disease (PD and Fabry disease. To test this relationship, we administered a self-report and family history questionnaire to determine the prevalence of PD in Fabry disease patients and family members with likely pathogenic alpha-galactosidase A (GLA mutations. A total of 90 Fabry patients (77 from the online survey and 13 from the Icahn School of Medicine at Mount Sinai (ISMMS were included in the analysis. Two of the Fabry disease patients who completed the online survey were diagnosed with PD (2/90, 2.2%. Among probands older than 60, 8.3% (2/24 were diagnosed with PD. Using Kaplan Meier survival analysis, the age-specific risk of PD by age 70 was 11.1%. Family history was available on 72 Fabry families from the online study and 9 Fabry families from ISMMS. Among these 81 families, 6 (7.4% had one first degree relative who fit the criteria for a conservative diagnosis of PD. The results of this study suggest that there may be an increased risk of developing PD in individuals with GLA mutations, but these findings should be interpreted with caution given the limitations of the study design.

The TB--Crohn's affair--a never ending dilemma.

Science.gov (United States)

Praveen, S; Razman, J

2008-08-01

An 80 year old lady presented with signs and symptoms of sub-acute intestinal obstruction which failed conservative management. CT scan abdomen revealed circumferential ileum thickening with proximal bowel dilatation. Laparotomy and segmental resection was done. Pathological findings were suggestive of chronic granulomatous ileits with differential of Crohn's disease and gastrointestinal tuberculosis. The patient was presumed to have gastrointestinal tuberculosis and commenced on anti tuberculosis treatment despite inconclusive evidence for confirmation and showed marked clinical improvement.

Disability weights for the Global Burden of Disease 2013 study

NARCIS (Netherlands)

Salomon, Joshua A.; Haagsma, Juanita A.; Davis, Adrian; de Noordhout, Charline Maertens; Polinder, Suzanne; Havelaar, Arie H.|info:eu-repo/dai/nl/072306122; Cassini, Alessandro; Devleesschauwer, Brecht; Kretzschmar, Mirjam; Speybroeck, Niko; Murray, Christopher J L; Vos, Theo

2015-01-01

Background: The Global Burden of Disease (GBD) study assesses health losses from diseases, injuries, and risk factors using disability-adjusted life-years, which need a set of disability weights to quantify health levels associated with non-fatal outcomes. The objective of this study was to estimate

Disability weights for the Global Burden of Disease 2013 study

NARCIS (Netherlands)

Salomon, Joshua A; Haagsma, Juanita A; Davis, Adrian; de Noordhout, Charline Maertens; Polinder, Suzanne; Havelaar, Arie H; Cassini, Alessandro; Devleesschauwer, Brecht; Kretzschmar, MEE; Speybroeck, Niko; Murray, Christopher J L; Vos, Theo

2015-01-01

BACKGROUND: The Global Burden of Disease (GBD) study assesses health losses from diseases, injuries, and risk factors using disability-adjusted life-years, which need a set of disability weights to quantify health levels associated with non-fatal outcomes. The objective of this study was to estimate

White matter changes contribute to corpus callosum atrophy in the elderly: The LADIS study

DEFF Research Database (Denmark)

Ryberg, C.; Rostrup, E.; Sjöstrand, Karl

2008-01-01

BACKGROUND AND PURPOSE: The corpus callosum (CC) is the most important structure involved in the transmission of interhemispheric information. The aim of this study was to investigate the potential correlation between regional age-related white matter changes (ARWMC) and atrophy of CC in elderly ...

Clinical audit of patients with cerebrovascular accident and transient ischemic attack in our lady of lourdes hospital drogheda, ireland

International Nuclear Information System (INIS)

Nagi, D.; Aamar, A.; Rahim, I.; Sadaf, M.I.

2012-01-01

Stroke is a major health problem and is one of leading causes of morbidity and mortality. Methods: A clinical audit comprising retrospective chart review of 101 patients randomly selected from admission register in Our Lady of Lourdes Hospital Drogheda, Ireland, was done during the first quarter of 2009. Keeping in view the recommendations, in this audit the following areas were evaluated: type of event, time of event and arrival to hospital, thrombolytic therapy, past medical history, investigations, smoking history, utilization of multidisciplinary services (physiotherapy and occupational therapy, speech and language therapy), medications, referral to GP, carotid pathology, and outcome. Results: Of the 101 patients, 43 (42.5%) were males and 58 (57.4%) were females. 47.5% (48/101) had TIA while 52.5% (53/101) had CVA. Of the total patients, 62.8% males and 56.8% females were hypertensive and 48.8% of males and 36.2% of females had hypercholesterolemia. Of the total number of patients, 23% of males and 15.5% of females were smokers. Utilization of different multidisciplinary services for males and females was following: physical therapy (46.5% and 45.8%); occupational therapy (11.6% and 15.3%); speech and language therapy (13.9% and 22%). Of all the patients 5% died in the hospital, 77.2% were discharged home and 17.8% were sent to Nursing home for long term care. Conclusion: The commonest risk factor for CVA / TIA is hypertension followed by hypercholesterolemia. Smoke cessation advice should be given to all at risk. (author)

Epithelioid Haemangioendothelioma (EHE) of the Liver.

Science.gov (United States)

Khan, Abidullah; Humayun, Mohammad; Haider, Iqbal; Khan, Wazir Muhammad; Ajmal, Fahad; Ayub, Maimoona

2016-06-01

A45-year previously known hypertensive lady presented with 2-year history of upper abdominal pain, heaviness, and weight loss. Her radiological assessment suggested the possibility of hepatoma or liver metastases. Considering her age, overall good health and absence of cirrhosis, a liver biopsy was taken which showed hepatic epithelioidhaemangioendothelioma (HEHE), a rare and unusual intermediate grade vascular tumor which can easily be confused with hepatoma or metastatic liver disease. To the best of their knowledge, the authors are most probably reporting the first ever case of HEHE from Pakistan with special emphasis on its clinical presentations, clinico-radiological diagnostic clues, and the management options in the light of the limited retrospective studies.

2001-2011

DEFF Research Database (Denmark)

Poggesi, Anna; Pantoni, Leonardo; Inzitari, Domenico

2011-01-01

of assessing the independent role of WMC in predicting disability in subjects aged 65-84. The main results of the LADIS study have been released in 2009 with the demonstration that severe WMC more than double the risk of transition from an autonomous to a dependent status after 3 years of follow-up. The LADIS...

Drosophila tools and assays for the study of human diseases

Directory of Open Access Journals (Sweden)

Berrak Ugur

2016-03-01

Full Text Available Many of the internal organ systems of Drosophila melanogaster are functionally analogous to those in vertebrates, including humans. Although humans and flies differ greatly in terms of their gross morphological and cellular features, many of the molecular mechanisms that govern development and drive cellular and physiological processes are conserved between both organisms. The morphological differences are deceiving and have led researchers to undervalue the study of invertebrate organs in unraveling pathogenic mechanisms of diseases. In this review and accompanying poster, we highlight the physiological and molecular parallels between fly and human organs that validate the use of Drosophila to study the molecular pathogenesis underlying human diseases. We discuss assays that have been developed in flies to study the function of specific genes in the central nervous system, heart, liver and kidney, and provide examples of the use of these assays to address questions related to human diseases. These assays provide us with simple yet powerful tools to study the pathogenic mechanisms associated with human disease-causing genes.

Aging and Alzheimer's Disease: Lessons from the Nun Study.

Science.gov (United States)

Snowdon, David A.

1997-01-01

Describes a woman who maintained high cognitive test scores until her death at 101 years of age despite anatomical evidence of Alzheimer's disease. The woman was part of a larger "Nun Study" in which 678 sisters donated their brains to teach others about the etiology of aging and Alzheimer's disease. Findings are discussed. (RJM)

A History of Radio Communications in the Baltimore District

Science.gov (United States)

1974-09-30

with WWI, World War I WWII, World War II XMTR, transmitter XYL, ex-young lady; wife YL, young lady Z, Zulu time, Greenwich mean time 73 or 73... tribe by that name. Through the years the spelling has been changed to its present form. On 20 December 1606 an expedition organized by the Virginia

Radioisotopic studies of bone diseases

International Nuclear Information System (INIS)

Ell, P.J.

1976-01-01

Consideration is given to the study of bone diseases. The most used radionuclides in the skeletal investigation are analysed and a table of radiopharmaceuticals of localization in the skeleton is showed. Emphasis is given to the use of Strontium 85 and 87m, fluorine 18 and technetium 99m. The phosphate compounds labelled with Technetium 99m are studied in detail and the structures of these organic and inorganic compounds are given. A table with values of the blood clearance of those compounds is presented. The skeletal distribution of the phosphate compounds-sup(99m)Tc, as well as the abnormal scintigraphy of skeleton by means of them, are analysed. Referring to bone diseases, the benign and malignant ones are studied: a table is given of bone diseases with positive imaging to the skeleton scintigraphy in the former case and the main applications of this scintigraphy in the latter one. Emphasis is given, in all the cases, to the clinical applications of the method, with recommendations in each one. Scintigraphic imagings are presented referring to each item studied [pt

PET-Studies in parkinson's disease

International Nuclear Information System (INIS)

Schwarz, J.

2002-01-01

Positron-emission-tomography (PET) has enabled to study the metabolism and blood flow in specific brain areas. Besides, there is a variety of radiotracers that allow quantification of the function of distinct molecules. In respect to Parkinson's disease, PET allowed for the first time to assess the number of dopaminergic neurons in vivo. Thus, helping confirming a dopaminergic deficit, measuring disease progression and also help to determine the function of dopaminergic grafts. Current research has shifted to determine the role of related neurotransmitter systems in the pathophysiology of Parkinson's disease. (orig.) [de

Hillary Clinton impressed by the Centre's work.

Science.gov (United States)

1995-01-01

In April 1994, US First Lady Hillary Rodham Clinton, her daughter Chelsea, the Bangladesh Minister for Women and Children's Affairs, and the US Ambassador to Bangladesh visited the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B). The First Lady remarked that ICDDR,B's research programs on health and family planning have many important lessons for the developing and developed regions alike. She noted the development successes in Bangladesh that can be applied in the US and other countries: the Grameen Bank, oral rehydration solution (ORS), and the community outreach programs for health and family planning services. The First Lady was especially interested in ORS and its cost-effectiveness. Most of the 220,000 children hospitalized each year in the US for severe gastrointestinal illness are treated with expensive intravenous (IV) drips (average cost = $2300), while a few ORS packets would be a small fraction of the cost. The average cost of treatment per patient at ICDDR,B was only $12. Patients receive care free of charge. Less than 0.6% of the patients die. The previous year, a USAID administrator asked ICDDR,B for its expertise in fighting cholera at the Rwandan refugee camps in Goma, Zaire. ICDDR,B staff developed diagnostic antisera for the new cholera strain responsible for the epidemic in the Americas, described its pathophysiology, and established its mode of transmission in surface waters. ICDDR,B also provides technical support to the national family planning and maternal and child health programs. In the Matlab, ICDDR,B's work has contributed to a high contraceptive prevalence rate of more than 64% among poor and largely illiterate persons.

The Prevalence of Fabry Disease in Patients with Chronic Kidney Disease in Turkey: The TURKFAB Study

Directory of Open Access Journals (Sweden)

Kultigin Turkmen

2016-12-01

Full Text Available Background/Aims: Fabry disease is a treatable cause of chronic kidney disease (CKD characterized by a genetic deficiency of α-galactosidase A. European Renal Best Practice (ERBP recommends screening for Fabry disease in CKD patients. However, this is based on expert opinion and there are no reports of the prevalence of Fabry disease in stage 1-5 CKD. Hence, we investigated the prevalence of Fabry disease in CKD patients not receiving renal replacement therapy. Methods: This prospective study assessed α-galactosidase activity in dried blood spots in 313 stage 1-5 CKD patients, 167 males, between ages of 18-70 years whose etiology of CKD was unknown and were not receiving renal replacement therapy. The diagnosis was confirmed by GLA gene mutation analysis. Results: Three (all males of 313 CKD patients (0.95% were diagnosed of Fabry disease, for a prevalence in males of 1.80%. Family screening identified 8 aditional Fabry patients with CKD. Of a total of 11 Fabry patients, 7 were male and started enzyme replacement therapy and 4 were female. The most frequent manifestations in male patients were fatigue (100%, tinnitus, vertigo, acroparesthesia, hypohidrosis, cornea verticillata and angiokeratoma (all 85%, heat intolerance (71%, and abdominal pain (57%. The most frequent manifestations in female patients were fatigue and cornea verticillata (50%, and tinnitus, vertigo and angiokeratoma (25%. Three patients had severe episodic abdominal pain attacks and proteinuria, and were misdiagnosed as familial Mediterranean fever. Conclusions: The prevalence of Fabry disease in selected CKD patients is in the range found among renal replacement therapy patients, but the disease is diagnosed at an earlier, treatable stage. These data support the ERBP recommendation to screen for Fabry disease in patients with CKD of unknown origin.

The study on risk factor of metabolic diseases in pancreatic steatosis

Energy Technology Data Exchange (ETDEWEB)

Cho, Jin Young; Ye, Soo Young; Kim, Dong Hyun [Dept. of Radiological Science, College of Health Sciences, Catholic University of Pusan, Busan (Korea, Republic of)

2016-03-15

The body of the fat tissue increased in obese represented by risk factors such as cardiovascular diseases, diabetes, metabolic disease and dyslipidemia. Such metabolic diseases and the like of the cardiovascular and cerebrovascular disease, hypertension, dyslipidemia, increase in the adipose tissue of the pancreas is known to be a risk factor of these diseases. Study on the diagnosis and treatment of pancreatic cancer was conducted actively, case studies on pancreatic steatosis is not much. In this study, divided into a control group diagnosed with pancreatic steatosis as a result of ultrasonography to evaluation the physical characteristics and serologic tests and blood pressure and arterial stiffness. The control group and the test pancreas steatosis age and waist circumference, body mass index, total cholesterol, HDL cholesterol, LDL cholesterol, and systolic and diastolic blood pressure, fasting blood glucose, arterial elasticity is higher in pancreatic steatosis. And the lower ankle brachial stenosis and HDLcholesterol were lower than the normal control group, so the pancreatic steatosis harmful to blood vessels.(P <0.05). The difference between the control group and it was confirmed that the pancreatic jibanggun statistically significant. In conclusion, pancreatic steatosis at abdominal ultrasound can predict the risk of metabolic diseases, and there was a correlation with cardiovascular disease.

The study on risk factor of metabolic diseases in pancreatic steatosis

International Nuclear Information System (INIS)

Cho, Jin Young; Ye, Soo Young; Kim, Dong Hyun

2016-01-01

The body of the fat tissue increased in obese represented by risk factors such as cardiovascular diseases, diabetes, metabolic disease and dyslipidemia. Such metabolic diseases and the like of the cardiovascular and cerebrovascular disease, hypertension, dyslipidemia, increase in the adipose tissue of the pancreas is known to be a risk factor of these diseases. Study on the diagnosis and treatment of pancreatic cancer was conducted actively, case studies on pancreatic steatosis is not much. In this study, divided into a control group diagnosed with pancreatic steatosis as a result of ultrasonography to evaluation the physical characteristics and serologic tests and blood pressure and arterial stiffness. The control group and the test pancreas steatosis age and waist circumference, body mass index, total cholesterol, HDL cholesterol, LDL cholesterol, and systolic and diastolic blood pressure, fasting blood glucose, arterial elasticity is higher in pancreatic steatosis. And the lower ankle brachial stenosis and HDLcholesterol were lower than the normal control group, so the pancreatic steatosis harmful to blood vessels.(P <0.05). The difference between the control group and it was confirmed that the pancreatic jibanggun statistically significant. In conclusion, pancreatic steatosis at abdominal ultrasound can predict the risk of metabolic diseases, and there was a correlation with cardiovascular disease

Autoimmune hepatitis in HIV: Case report | Kamau | East African ...

African Journals Online (AJOL)

We present a middle aged lady positive HIV who developed liver disease one year after initiation of anti-retroviral therapy (ART). Laboratory and histo pathology finding supported a diagnosis of autoimmune hepatitis (AIH). She responded well to immuno-suppressive therapy and is currently doing well on maintenance ...

[Rasagiline is not for all Parkinson disease patients: the ADAGIO study].

NARCIS (Netherlands)

Laar, T. van; Boon, A.J.; Bloem, B.R.

2010-01-01

Rasagiline is a MAO-B inhibitor that is currently registered for the symptomatic treatment of Parkinson disease. The ADAGIO trial studied the potential disease-modifying properties of rasagiline in 1100 patients with Parkinson disease, using an innovative 'delayed start' design. Patients were

Callosal tissue loss parallels subtle decline in psychomotor speed. A longitudinal quantitative MRI study. The LADIS Study

NARCIS (Netherlands)

Jokinen, H.; Frederiksen, K.S.; Garde, E.; Skimminge, A.; Siebner, H.; Waldemar, G.; Ylikoski, R.; Madureira, S.; Verdelho, A.; van Straaten, E.C.W.; Barkhof, F.; Fazekas, F.; Schmidt, R.; Pantoni, L.; Inzitari, D.; Erkinjuntti, T.

2012-01-01

Cross-sectional studies have suggested that corpus callosum (CC) atrophy is related to impairment in global cognitive function, mental speed, and executive functions in the elderly. Longitudinal studies confirming these findings have been lacking. We investigated whether CC tissue loss is associated

Periodontal disease in pregnant patients with rheumatic valvular disease: clinical and microbiological study.

Science.gov (United States)

Avila, Walkiria Samuel; Timerman, Lilia; Romito, Giuseppe Alexandre; Marcelino, Sílvia Linard; Neves, Itamara Lúcia Itagiba; Zugaib, Marcelo; Grinberg, Max

2011-04-01

The periodontal disease during pregnancy of women with rheumatic valve disease imply infective endocarditis risks and higher rate of preterm birth and low birth weight. To study the periodontal disease rate of women with rheumatic valve disease during pregnancy. We studied 140 pregnant women who included 70 patients with rheumatic valve disease and 70 healthy women. The periodontal examination included: 1) periodontal clinical exam regard the follow variables: a) probing depth; b) gingival margin; c) clinical attachment level; d) bleeding on probing; e) plaque index and f) gingival index; and 2) microbiological test was performed in samples serum and gingival crevicular fluid and considered positive controls to Porphyromonas gingivalis, Tannerella forsithia e Aggregobacter actinomycetemcomitans. Age and parity were similar between groups; as single or combined the mitral valve disease was prevalent among the rheumatic valve lesion in 45 (32.1%) e 20 (28.5%) cases, respectively. Among the periodontal variables gingival margin (p=0.01) and plaque index (p=0.04) were different between groups. The periodontal disease was identified in 20 (14,3%) pregnant women, seven (10%) of them were patients with valve rheumatic disease and the remain 13 (18,6%) were healthy women, its percentual was not different between groups (p=0,147). Microbiological analyses of oral samples showed higher percentual of P. gingivalis in healthy pregnant women (p=0.004). The clinical and microbiological study during pregnancy showed comparable incidence of periodontal disease between women with rheumatic valve disease and healthy women.

Spreading the cult body on YouTube: A case study of "Telephone" derivative videos

Directory of Open Access Journals (Sweden)

Agnese Vellar

2012-03-01

Full Text Available This case study of spreadability analyzes the Lady Gaga music video "Telephone," which has been appropriated and reworked by YouTube users sharing derivative works online. What properties of the music video stimulate user appropriation? What hybrid audiovisual forms are emerging from its reworking by users? In order to answer these questions, between January and August 2010, I conducted participant observation on Lady Gaga's official social network profiles and collected 70 "Telephone" derivative videos on YouTube. I identified three main categories of video creativity: (1 music (which includes covers, "me singing" videos, music mashups, and choreography; (2 parody (in which YouTube users and comedians humorously imitate Gaga, creating spoofs; and (3 fashion (in which makeup artists and amateurs appropriate the star's image to create makeup and hair tutorials. "Telephone" has become spreadable because it integrates dance music and choreography, costume changes, cinematic references, and product placements that work as textual hooks meaningful to different target markets: live music, dance, chick, and postmodern cinematic cultures. In particular, Gaga is a cult body that explicitly incorporates previous cinematic and pop music icons. Users are stimulated to reenact Gaga's cult body online. On YouTube, spreadability is thus strictly related to the appropriation of cult bodies. Fans, comedians, independent musicians, fashionistas, and pop stars construct their own cult bodies by deliberately borrowing characteristics from previous media icons and reenacting them in online videos in order to fulfill their expressive and professional needs.

A Metabolic Study of Huntington's Disease.

Directory of Open Access Journals (Sweden)

Rajasree Nambron

Full Text Available Huntington's disease patients have a number of peripheral manifestations suggestive of metabolic and endocrine abnormalities. We, therefore, investigated a number of metabolic factors in a 24-hour study of Huntington's disease gene carriers (premanifest and moderate stage II/III and controls.Control (n = 15, premanifest (n = 14 and stage II/III (n = 13 participants were studied with blood sampling over a 24-hour period. A battery of clinical tests including neurological rating and function scales were performed. Visceral and subcutaneous adipose distribution was measured using magnetic resonance imaging. We quantified fasting baseline concentrations of glucose, insulin, cholesterol, triglycerides, lipoprotein (a, fatty acids, amino acids, lactate and osteokines. Leptin and ghrelin were quantified in fasting samples and after a standardised meal. We assessed glucose, insulin, growth hormone and cortisol concentrations during a prolonged oral glucose tolerance test.We found no highly significant differences in carbohydrate, protein or lipid metabolism markers between healthy controls, premanifest and stage II/III Huntington's disease subjects. For some markers (osteoprotegerin, tyrosine, lysine, phenylalanine and arginine there is a suggestion (p values between 0.02 and 0.05 that levels are higher in patients with premanifest HD, but not moderate HD. However, given the large number of statistical tests performed interpretation of these findings must be cautious.Contrary to previous studies that showed altered levels of metabolic markers in patients with Huntington's disease, our study did not demonstrate convincing evidence of abnormalities in any of the markers examined. Our analyses were restricted to Huntington's disease patients not taking neuroleptics, anti-depressants or other medication affecting metabolic pathways. Even with the modest sample sizes studied, the lack of highly significant results, despite many being tested, suggests that

Radionuclide study for the interstitial lung disease

International Nuclear Information System (INIS)

Kawakami, Kenji; Mori, Yutaka; Ujita, Masuo

1991-01-01

The contribution of pulmonary nuclear medicine was evaluated in 105 patients with interstitial pulmonary diseases (IPD). Ventilation study (V) with 81m Kr, distribution of compliance in thoraco-pulmonary system (C) by 81m Kr gas bolus inhalation method, perfusion study (Q) with 99m Tc-MAA, 67 Ga scintigraphy and an assessment of pulmonary epithelial permeability with 99m Tc-DTPA aerosol were performed as nuclear medicine procedures. Pulmonary function test (%DLco, vital capacity and functional residual capacity) and blood gas analysis were also examined. Abnormalities in V were larger than that in Q which was high V/Q mismatch finding, in the interstitial pneumonia. Correlation between V/Q mismatch and PaO 2 was, therefore, not significant. %DLco was decreased in cases with larger V/Q mismatches. 67 Ga accumulated in the early stage of interstitial pneumonia when CT or chest X-ray did not show any finding. %DLco was decreased in cases with strong accumulation of 67 Ga. 67 Ga might be useful to evaluate activity of the diseases. Pulmonary epithelial permeability was assessed by 99m Tc-DTPA inhalation study. This permeability accelerated in idiopathic interstitial fibrosis and sarcoidosis. Pulmonary epithelial permeability may be useful as an indicator for epithelial cell injury. (author)

Neuroimaging Studies Illustrate the Commonalities Between Ageing and Brain Diseases.

Science.gov (United States)

Cole, James H

2018-07-01

The lack of specificity in neuroimaging studies of neurological and psychiatric diseases suggests that these different diseases have more in common than is generally considered. Potentially, features that are secondary effects of different pathological processes may share common neurobiological underpinnings. Intriguingly, many of these mechanisms are also observed in studies of normal (i.e., non-pathological) brain ageing. Different brain diseases may be causing premature or accelerated ageing to the brain, an idea that is supported by a line of "brain ageing" research that combines neuroimaging data with machine learning analysis. In reviewing this field, I conclude that such observations could have important implications, suggesting that we should shift experimental paradigm: away from characterizing the average case-control brain differences resulting from a disease toward methods that place individuals in their age-appropriate context. This will also lead naturally to clinical applications, whereby neuroimaging can contribute to a personalized-medicine approach to improve brain health. © 2018 WILEY Periodicals, Inc.

Myocardial perfusion studies in coronary diseases

International Nuclear Information System (INIS)

Mut, Fernando

1994-01-01

For detecting in precocious form a coronary disease is necessary to apply a diagnostic techniques. The main considerations to be indicated in the present work are: physiological considerations, myocardial perfusion studies with radiotracers such as Talio 201, 99mTc, MIBI, 99mTc-Teboroxima, 99mTc-Fosfinas, instrumentation for obtain good images,proceedings protocols, studies interpretation, standards, SPECT, anomalies standards, coronary diseases

CT study in Alzheimer's disease

Energy Technology Data Exchange (ETDEWEB)

Arai, Heii; Kobayashi, Kazunari; Ikeda, Kenji; Nagao, Yoshiko; Ogihara, Ryuji; Kosaka, Kenji [Tokyo Metropolitan Matsuzawa Hospital (Japan)

1983-01-01

Cerebral atrophy on CT was studied in 18 patients with clinically diagnosed Alzheimer's disease and in 14 healthy age-matched subjects as the control. The patients with Alzheimer's disease were divided into three groups of Stages I, II and III, according to their clinical symptoms. The study of the measurement method disclosed that the computerized measurement involving calculation of the number of pixels contained within the range of the designated CT numbers is liable to produce errors for the determination of the subarachnoid spaces and the ventricles with calcified colloid plexus. Therefore, for the present study was the method adopted, in which the subarachnoid spaces and the ventricles are measured based on the number of pixels contained in the region of interest by tracing them on the display monitor. Then, both Subarachnoid Space Volume Index (SVI) and Ventricle Volume Index (VVI) were calculated as the indices for cortical atrophy and ventricular dilatation in a slice through the level of the foramen interventriculare Monroi and other three successive ones through upper regions. Cerebral atrophy observed on CT in Alzheimer patients is attributable to Alzheimer's disease processes, rather than to physiological aging of the brain. The degree of the atrophy increases in proportion to the clinical stage, and cortical atrophy is apparent even at Stage I, whereas ventricular dilatation becomes pronounced at later stage. CT is one of effective clinical tests for the diagnosis of Alzheimer's disease.

CT study in Alzheimer's disease

International Nuclear Information System (INIS)

Arai, Heii; Kobayashi, Kazunari; Ikeda, Kenji; Nagao, Yoshiko; Ogihara, Ryuji; Kosaka, Kenji

1983-01-01

Cerebral atrophy on CT was studied in 18 patients with clinically diagnosed Alzheimer's disease and in 14 healthy age-matched subjects as the control. The patients with Alzheimer's disease were divided into three groups of Stages I, Ii and III, according to their clinical symptoms. The study of the measurement method disclosed that the computerized measurement involving calculation of the number of pixels contained within the range of the designated CT numbers is liable to produce errors for the determination of the subarachnoid spaces and the ventricles with calcified colloid plexus. Therefor, for the present study was the method adopted, in which the subarachnoid spaces and the ventricles are measured based on the number of pixels contained in the region of interest by tracing them on the display monitor. Then, both Subarachnoid Space Volume Index (SVI) and Ventricle Volume Index (VVI) were calculated as the indices for cortical atrophy and ventricular dilatation in a slice through the level of the foramen interventriculare Monroi and other three successive ones through upper regions. Cerebral atrophy observed on CT in Alzheimer patients is attributable to Alzheimer's disease processes, rather than to physiological aging of the brain. The degree of the atrophy increases in proportion to the clinical stage, and cortical atrophy is apparent even at Stage I, whereas ventricular dilatation becomes pronounced at later stage. CT is one of effective clinical tests for the diagnosis of Alzheimer's disease. (J.P.N.)

The association between periodontal disease and chronic obstructive pulmonary disease: a case control study.

Science.gov (United States)

Öztekin, Görkem; Baser, Ulku; Kucukcoskun, Meric; Tanrikulu-Kucuk, Sevda; Ademoglu, Evin; Isik, Gulden; Ozkan, Gulcihan; Yalcin, Funda; Kiyan, Esen

2014-08-01

Although there are studies evaluating the effects of periodontal health on chronic obstructive pulmonary disease (COPD), the effects of COPD - a systemic disease, on periodontal tissue is unknown. The aim of this study is to evaluate the effects of COPD on periodontal tissues by comparing COPD patients and controls. Fifty-two COPD patients and 38 non-COPD controls were included in this case-control study. Number of teeth, plaque index (PI), gingival index (GI), bleeding on probing, clinical attachment level and probing depth were included in the periodontal examination. In addition to clinical evaluations, gingival crevicular fluid (GCF) levels of high-sensitive C-reactive protein (hs-CRP), interleukin-1 beta (IL-lb) and prostaglandin-E2 (PGE2), and serum hs-CRP levels were measured in COPD patients and the controls. The number of teeth was significantly lower while PI and GI were significantly higher in COPD patients when compared to the controls. As well as serum hs-CRP levels, the GCF levels of hs-CRP, IL-1b and PGE2 were significantly higher in COPD patients than the controls. Our results demonstrated that COPD may be associated with periodontal disease as manifested by lower number of teeth and higher levels of inflammatory mediators especially CRP in GCF. This finding may be a reflection of systemic effects of COPD on periodontal tissues. Poor oral health behavior of COPD patients have to be considered in larger size group studies in the future.

Coronary artery disease in patients with cerebrovascular disease: a prospective study

International Nuclear Information System (INIS)

Rokey, R.; Rolak, L.A.; Harati, Y.; Kutka, N.; Verani, M.S.

1984-01-01

Coronary artery disease is the cause of death in most patients who have transient ischemic attacks or stroke. Evaluation for this condition is not routinely performed in such patients, and no prospective studies have been reported. We prospectively examined 50 consecutive patients with transient ischemic attacks or mild stroke to determine the prevalence and importance of coronary artery disease. All patients were examined by a cardiologist and underwent both exercise thallium-201 scintigraphy and exercise radionuclide ventriculography. Sixteen patients were suspected to have coronary artery disease on the basis of clinical evaluation. In 15 of these the was confirmed by the nuclear scans. The remaining 34 patients had no clinical evidence of heart disease, yet 14 had abnormal cardiac scans. Twenty of 22 patients with abnormal scans who underwent cardiac catheterization had significant coronary artery disease or a cardiomyopathy. The discovery of heart disease altered clinical management in 13 patients. Overall, 29 of 50 patients had significant coronary artery disease, compared with a 7% prevalence of the condition in other patients of similar age at the same institution

Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities: the LADIS Study

DEFF Research Database (Denmark)

Jokinen, Hanna; Ryberg, Charlotte; Kalska, Hely

2007-01-01

BACKGROUND: Previous research has indicated that corpus callosum atrophy is associated with global cognitive decline in neurodegenerative diseases, but few studies have investigated specific cognitive functions. OBJECTIVE: To investigate the role of regional corpus callosum atrophy in mental speed...... of the total corpus callosum area and its subregions with cognitive performance were analysed using multiple linear regression, controlling for volume of WMH and other confounding factors. RESULTS: Atrophy of the total corpus callosum area was associated with poor performance in tests assessing speed of mental...... processing--namely, trail making A and Stroop test parts I and II. Anterior, but not posterior, corpus callosum atrophy was associated with deficits of attention and executive functions as reflected by the symbol digit modalities and digit cancellation tests, as well as by the subtraction scores in the trail...

Corpus callosum atrophy is associated with mental slowing and executive deficits in subjects with age-related white matter hyperintensities. The LADIS study

DEFF Research Database (Denmark)

Jokinen, Hanne; Ryberg, Charlotte; Stegmann, Mikkel Bille

2007-01-01

Background: Previous research has indicated that corpus callosum atrophy is associated with global cognitive decline in neurodegenerative diseases, but few studies have investigated specific cognitive functions. Objective: To investigate the role of regional corpus callosum atrophy in mental speed...... of the total corpus callosum area and its subregions with cognitive performance were analysed using multiple linear regression, controlling for volume of WMH and other confounding factors. Results: Atrophy of the total corpus callosum area was associated with poor performance in tests assessing speed of mental...... processing - namely, trail making A and Stroop test parts I and II. Anterior, but not posterior, corpus callosum atrophy was associated with deficits of attention and executive functions as reflected by the symbol digit modalities and digit cancellation tests, as well as by the subtraction scores...

The epidemiologic study of children diseases under one year in Tehran

Directory of Open Access Journals (Sweden)

Babaeei Gh

2001-07-01

Full Text Available Infant mortality and morbidity present important challenges to those concerned with community health. We did this research to study epidemiology of diseases of infancy in city of Tehran. During 15 days, of 6395 deliveries in Tehran hospitals a cohort of 6267 live births entered this study. Follow up data were gathered in 1st, 3rd, 6th and 12th months of birth. In this period, 5382 occurrence of disease were reported. The most frequent were cardiopulmonary (52.3% and Gastrointestinal (26.6% diseases. Most of the events were seen in 6-12 months age group (30.5%. The lowest frequencies of infant diseases were seen in 19-35 years of maternal age (15.3%, as compared with >35 (35.4% and <19 (49.3% groups. Mortality ratio was 32/1000 live birth (198 death. The most common causes of death were cardiopulmonary (38%, infectious (21% and gastrointestinal (18% diseases. Control of infectious disease, development of educational programs for breast feeding and planning of proper age and interval of pregnancy are effective measures for reducing infant mortality and morbidity.

Theatre and Cultural Diplomacy: The Role of the Performing Arts in How Nations Deal With Each Other

Science.gov (United States)

2010-06-01

after the outbreak of war, in Malines in Belgium, where prisoners of French, German, Flemish, and Dutch origins were interned, the SS arranged for...in 1917, seven ladies of theatre-Rachel Crothers, Louise Closser Hale, Dorothy Donnelly, Josephine Hull, Minnie Dupree, Bessie Tyree and Louise Drew...converged to discuss the possibility of forming an organization to aid in war relief. At the meeting, these ladies decided to summon members of the

The importance of studying sex differences in disease: The example of multiple sclerosis.

Science.gov (United States)

Golden, Lisa C; Voskuhl, Rhonda

2017-01-02

To date, scientific research has often focused on one sex, with assumptions that study of the other sex would yield similar results. However, many diseases affect males and females differently. The sex of a patient can affect the risk for both disease susceptibility and progression. Such differences can be brought to the laboratory bench to be investigated, potentially bringing new treatments back to the clinic. This method of research, known as a "bedside to bench to bedside" approach, has been applied to studying sex differences in multiple sclerosis (MS). Females have greater susceptibly to MS, while males have worse disease progression. These two characteristics of the disease are influenced by the immune system and the nervous system, respectively. Thus, sex differences in each system must be studied. Personalized medicine has been at the forefront of research recently, and studying sex differences in disease fits with this initiative. This review will discuss the known sex differences in MS and highlight how investigating them can lead to new insights and potential treatments for both men and women. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

Epidemiology of Parkinson's Disease: The Rotterdam Study

NARCIS (Netherlands)

M.C. de Rijk (Maarten)

1997-01-01

textabstractAt present, Parkinson's disease (PO), after Alzheimer's disease, is generally considered to be the most frequent progressive neurodegenerative disease in the elderly. Due to the growing proportion of elderly in many populations, more and more persons will be affected by this disabling

Endometriosis research: animal models for the study of a complex disease.

Science.gov (United States)

Tirado-González, Irene; Barrientos, Gabriela; Tariverdian, Nadja; Arck, Petra C; García, Mariana G; Klapp, Burghard F; Blois, Sandra M

2010-11-01

Endometriosis is a common gynaecological disease that is characterized and defined as the presence of endometrial tissue outside the uterus, causing painful periods and subfertility in approximately 10% of women. After more than 50 years of research, little is known about the mechanisms underlying the development and establishment of this condition. Animal models allow us to study the temporal sequence of events involved in disease establishment and progression. Also, because this disease occurs spontaneously only in humans and non-human primates and there are practical problems associated with studying the disease, animal models have been developed for the evaluation of endometriosis. This review describes the animal models for endometriosis that have been used to date, highlighting their importance for the investigation of disease mechanisms that would otherwise be more difficult to elucidate, and proposing new alternatives aimed at overcoming some of these limitations. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Innovative measures to combat rare diseases in China: The national rare diseases registry system, larger-scale clinical cohort studies, and studies in combination with precision medicine research.

Science.gov (United States)

Song, Peipei; He, Jiangjiang; Li, Fen; Jin, Chunlin

2017-02-01

China is facing the great challenge of treating the world's largest rare disease population, an estimated 16 million patients with rare diseases. One effort offering promise has been a pilot national project that was launched in 2013 and that focused on 20 representative rare diseases. Another government-supported special research program on rare diseases - the "Rare Diseases Clinical Cohort Study" - was launched in December 2016. According to the plan for this research project, the unified National Rare Diseases Registry System of China will be established as of 2020, and a large-scale cohort study will be conducted from 2016 to 2020. The project plans to develop 109 technical standards, to establish and improve 2 national databases of rare diseases - a multi-center clinical database and a biological sample library, and to conduct studies on more than 50,000 registered cases of 50 different rare diseases. More importantly, this study will be combined with the concept of precision medicine. Chinese population-specific basic information on rare diseases, clinical information, and genomic information will be integrated to create a comprehensive predictive model with a follow-up database system and a model to evaluate prognosis. This will provide the evidence for accurate classification, diagnosis, treatment, and estimation of prognosis for rare diseases in China. Numerous challenges including data standardization, protecting patient privacy, big data processing, and interpretation of genetic information still need to be overcome, but research prospects offer great promise.

The behaviour of radiocaesium in woodland ecosystems. Measurement and modelling

International Nuclear Information System (INIS)

Toal, M.

1999-02-01

In order to better quantify risk to non-human biota from environmental radioactivity, our understanding of the behaviour of radionuclides in the biosphere needs to be increased. Hence the aims of the present study were threefold: 1) Review Ecological Risk Assessment (ERA) methodologies, 2) Quantify radiocaesium distribution in woodland biota in the vicinity of BNFL Sellafield, 3) Use this information to develop radiocaesium food-chain and dosimetry models for terrestrial invertebrates and small-mammals. A review of ERA literature concluded that of the two main methodologies available (individual receptor and holistic ERA), individual receptor based analysis is the most credible method given in today's level of scientific understanding. lt was also concluded that the use of modelling techniques in ERA will increase in future years. Two study sites were sampled, a Picea sitchensis monoculture (Lady Wood) and a mixed deciduous site (Longrigg Wood). Mean levels of Cs-137 (all activities quoted in Bq/kg dry weight) in soils:leaf litter were 473:408 (Lady Wood) and 142:32 (Longrigg Wood). The activity of understorey vegetation varied with ranges of 17-508 and 4-48 Bq/kg in Lady Wood and Longrigg, respectively. No vegetation species had concentration ratios (CRs) > 1. The greatest range in Cs-137 activity (2-5242 Bq/kg DW, Lady Wood) was found in fungi, with Mycena galariculata and Hypholoma fasciculare attaining the highest biomagnifications (CRs = 2.6, 2.0 respectively). Due to radioanalytical constraints, only 'mixed invertebrate' samples were measured for Longrigg Wood (yearly average = 8.5 Bq/kg). No significant invertebrate body-burden differences were found between taxa or between seasons for each invertebrate group in Lady Wood. Mean yearly Cs-137 body-burdens (Bq/kg DW) were 94 (Diplopoda), 104 (Isopoda), 54 (Chilopoda), 120 (Araneae), 91 (Opilionidae) and 41 (Carabidae). No invertebrates had CRs > 1. Seasonal Cs-137 body-burdens were also measured for the

Radionuclide study for the interstitial lung disease

Energy Technology Data Exchange (ETDEWEB)

Kawakami, Kenji; Mori, Yutaka; Ujita, Masuo (Jikei Univ., Tokyo (Japan). School of Medicine)

1991-07-01

The contribution of pulmonary nuclear medicine was evaluated in 105 patients with interstitial pulmonary diseases (IPD). Ventilation study (V) with {sup 81m}Kr, distribution of compliance in thoraco-pulmonary system (C) by {sup 81m}Kr gas bolus inhalation method, perfusion study (Q) with {sup 99m}Tc-MAA, {sup 67}Ga scintigraphy and an assessment of pulmonary epithelial permeability with {sup 99m}Tc-DTPA aerosol were performed as nuclear medicine procedures. Pulmonary function test (%DLco, vital capacity and functional residual capacity) and blood gas analysis were also examined. Abnormalities in V were larger than that in Q which was high V/Q mismatch finding, in the interstitial pneumonia. Correlation between V/Q mismatch and PaO{sub 2} was, therefore, not significant. %DLco was decreased in cases with larger V/Q mismatches. {sup 67}Ga accumulated in the early stage of interstitial pneumonia when CT or chest X-ray did not show any finding. %DLco was decreased in cases with strong accumulation of {sup 67}Ga. {sup 67}Ga might be useful to evaluate activity of the diseases. Pulmonary epithelial permeability was assessed by {sup 99m}Tc-DTPA inhalation study. This permeability accelerated in idiopathic interstitial fibrosis and sarcoidosis. Pulmonary epithelial permeability may be useful as an indicator for epithelial cell injury. (author).

Comparative assessment of the prevalence of periodontal disease in subjects with and without systemic autoimmune diseases: A case-control study.

Science.gov (United States)

Ramesh Kumar, S G; Aswath Narayanan, M B; Jayanthi, D

2016-01-01

Immune mechanism shares a common pathway both for systemic autoimmune diseases and periodontal diseases. Scientific exploration of literature revealed limited studies on the association between systemic autoimmune diseases and periodontal diseases in India. The aim of the study is to find whether the presence of systemic autoimmune diseases in an individual is a risk factor for the development of periodontal disease. This was a hospital-based case-control study. A sample of 253 patients with systemic autoimmune diseases, attending the Rheumatology Department of Government General Hospital, Chennai-3, and 262 patients without systemic autoimmune diseases, attending the outpatient department of the Tamil Nadu Government Dental College and Hospital, Chennai-3, constituted the case and control groups, respectively. Age, gender, and oral hygiene status matching was done. Oral hygiene status was assessed using oral hygiene index (OHI) and periodontal status was assessed using community periodontal index (CPI) and loss of attachment (LOA) index. Statistical analysis was done using SPSS version 15 (SPSS Inc, 2006, Chicago). Results showed 99.2% and 73.9% prevalence of gingivitis and periodontitis, respectively, in the case group as compared to 85.5% and 14.9%, respectively, in the control group. There is no linear relationship between OHI scores and prevalence of periodontitis (CPI and LOA scores) in the case group. Patients suffering from systemic autoimmune diseases showed more prevalence of periodontal diseases irrespective of oral hygiene scores. It is postulated that the presence of systemic autoimmune diseases may pose a risk for the development of periodontal diseases.

Phenylketonuria patients' and their parents' acceptance of the disease: multi-centre study.

Science.gov (United States)

Witalis, Ewa; Mikoluc, Bożena; Motkowski, Radoslaw; Szyszko, Justyna; Chrobot, Agnieszka; Didycz, Bozena; Lange, Agata; Mozrzymas, Renata; Milanowski, Andrzej; Nowacka, Maria; Piotrowska-Depta, Mariola; Romanowska, Hanna; Starostecka, Ewa; Wierzba, Jolanta; Skorniewska, Magdalena; Wojcicka-Bartlomiejczyk, Barbara Iwona; Gizewska, Maria

2016-11-01

Phenylketonuria (PKU) still poses a therapeutic challenge for patients and medical professionals. The aim of the study was to assess both patients' and their parents' acceptance of the disease. The study included 218 PKU patients and 178 parents of PKU children who were enrolled in the study on the basis of questionnaire data. Regarding attitude towards the disease, our study demonstrated that 63 (28.9 %) PKU patients did not accept the disease. Patients who found accepting the disease difficult, more frequently perceived themselves as inferior/different in comparison with their peers. In total, 36 % of patients did not want their friends to be aware of their condition, while only 18 % of parents believed that their children's peers should not know about their disease. In total, 42 % of parents wanted to talk to other parents of PKU children and only 13 % to a doctor. Only 20 % of patients saw the need to discuss their condition with a doctor. In total, 8 % of children, regardless of age, and 14 % of parents preferred to talk to a psychologist. Our data demonstrated that disease acceptance played an essential role in patients' social integration. The study also indicated the need to overcome communication barriers between patients and their healthy peers and for patients to find the courage to be open about the disease. The importance of support groups for PKU families and the significance of strict cooperation between patients and their families with PKU treatment teams were also revealed.

Cryptogenic Organising Pneumonia As The Initial Presenting Manifestation of SLE

Directory of Open Access Journals (Sweden)

Neena Mampilly

2015-07-01

Full Text Available Cryptogenic Organising Pneumonia (COP, also called idiopathic Bronchiolitis Obliterans Organising Pneumonia( BOOP, is a distinct entity among the idiopathic interstitial pneumonias defined histopathologically by intraalveolar buds of granulation tissue. The etiology includes idiopathic, infectious, drug induced radiation induced and connective tissue diseases. Organising pneumonia occurs particularly in patients with dermatomyositis-polymyositis where it may be the presenting manifestation, and rarely in SLE, rheumatoid arthritis, scleroderma and other connective tissue diseases. We describe a 30 yr old lady who initially presented with respiratory symptoms, not responding to antibiotics. She was subsequently diagnosed as SLE and HRCT thorax showed consolidation involving both lung fields. A percutaneous lung biopsy revealed features of Cryptogenic Organising Pneumonia.

Implications of Integrating Women into the Marine Corps Infantry

Science.gov (United States)

2015-12-01

Rights Commission, 2013. 14 Randazzo-Matsel, Schulte, and Yopp, 2012; Anne Summers, “The Lady Killers : Women in the Military,” The Monthly, December 2011...individual and crew-served weapons, optics, image enhancement equipment, and other serialized items. Leadership and education PME: Issues concerning...United Kingdom, June 2010. Summers, Anne, “The Lady Killers : Women in the Military,” The Monthly, December 2011. “Swedish Women Troops Want ‘Combat

Systematic Review on the Definition of Allergic Diseases in Children : The MeDALL Study

NARCIS (Netherlands)

Pinart, Mariona; Albang, Richard; Maier, Dieter; Duran-Tauleria, Enric; Mena, Guillermo; Gimeno-Santos, Elena; Solà, Ivan; Garcia-Aymerich, Judith; Guerra, Stefano; Stein, Renato T; Benet, Marta; Carlsen, Kai-Håkon; Herr, Marie; Jacquemin, Bénédicte; Momas, Isabelle; Pin, Isabelle; Rancière, Fanny; Smit, Henriëtte A; Varraso, Raphaelle; Bonfill, Xavier; Keil, Thomas; Bousquet, Jean; Antó, Josep M

2015-01-01

BACKGROUND: During the last decades, a large number of phenotypes and disease classifications of allergic diseases have been proposed. Despite the heterogeneity across studies, no systematic review has been conducted on phenotype classification and the criteria that define allergic diseases. We

Metastatic transitional cell carcinoma of the tibia radiologically mimicking osteosarcoma.

LENUS (Irish Health Repository)

Cunningham, Laurence Patrick

2013-01-01

We report a case of a 73-year-old lady with transitional cell carcinoma and no evidence of metastatic disease presenting with gradual weight loss, pretibial swelling and painful weightbearing. Investigations revealed a lesion of the right tibial diaphysis. The radiological and clinical appearance was that of primary osteosarcoma. Biopsy results revealed metastatic transitional cell carcinoma of the tibia. Intramedullary nailing was performed which relieved pain on weightbearing. The patient declined radiotherapy and was started on a palliative care regimen. This case illustrates the importance of histological diagnosis in the treatment of diaphyseal lesions.

A Case-Control study of the prevalence of neurological diseases in inflammatory bowel disease (IBD

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Francisco de Assis Aquino Gondim

2015-02-01

Full Text Available Neurological diseases are common in inflammatory bowel disease (IBD patients, but their exact prevalence is unknown. Method We prospectively evaluated the presence of neurological disorders in 121 patients with IBD [51 with Crohn's disease (CD and 70 with ulcerative colitis (UC] and 50 controls (gastritis and dyspepsia over 3 years. Results Our standard neurological evaluation (that included electrodiagnostic testing revealed that CD patients were 7.4 times more likely to develop large-fiber neuropathy than controls (p = 0.045, 7.1 times more likely to develop any type of neuromuscular condition (p = 0.001 and 5.1 times more likely to develop autonomic complaints (p = 0.027. UC patients were 5 times more likely to develop large-fiber neuropathy (p = 0.027 and 3.1 times more likely to develop any type of neuromuscular condition (p = 0.015. Conclusion In summary, this is the first study to prospectively establish that both CD and UC patients are more prone to neuromuscular diseases than patients with gastritis and dyspepsia.

Mortality due to noncommunicable diseases in Brazil, 1990 to 2015, according to estimates from the Global Burden of Disease study

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Deborah Carvalho Malta

Full Text Available ABSTRACT CONTEXT AND OBJECTIVE: Noncommunicable diseases (NCDs are the leading health problem globally and generate high numbers of premature deaths and loss of quality of life. The aim here was to describe the major groups of causes of death due to NCDs and the ranking of the leading causes of premature death between 1990 and 2015, according to the Global Burden of Disease (GBD 2015 study estimates for Brazil. DESIGN AND SETTING: Cross-sectional study covering Brazil and its 27 federal states. METHODS: This was a descriptive study on rates of mortality due to NCDs, with corrections for garbage codes and underreporting of deaths. RESULTS: This study shows the epidemiological transition in Brazil between 1990 and 2015, with increasing proportional mortality due to NCDs, followed by violence, and decreasing mortality due to communicable, maternal and neonatal causes within the global burden of diseases. NCDs had the highest mortality rates over the whole period, but with reductions in cardiovascular diseases, chronic respiratory diseases and cancer. Diabetes increased over this period. NCDs were the leading causes of premature death (30 to 69 years: ischemic heart diseases and cerebrovascular diseases, followed by interpersonal violence, traffic injuries and HIV/AIDS. CONCLUSION: The decline in mortality due to NCDs confirms that improvements in disease control have been achieved in Brazil. Nonetheless, the high mortality due to violence is a warning sign. Through maintaining the current decline in NCDs, Brazil should meet the target of 25% reduction proposed by the World Health Organization by 2025.

The investigation of the lateral atlanto-dental interval of atlanto-axial joint by multi-slice spiral CT

International Nuclear Information System (INIS)

Cui Wei; Peng Lei; Wang Jincai; Liu Jihua; Feng Weihua

2010-01-01

Objective: To explore imaging features of the lateral atlanto-dental interval (LADI) of atlanto-axial joint and its value in the diagnosis of atlanto-axial joint dislocation/subluxation. Methods: Two hundred and forty healthy volunteers without atlanto-axial joint dysfunction and 32 patients with torticollis and/or functional impairment at atlanto-axial.joint were enrolled into this study. All subjects were examined with multi-slice CT in both neutral and max rotation positions to the left/right. Clinical endpoints including VBLADI, variance range of the VBLADI and asymmetric conditions were evaluate. χ 2 test is used to evaluate the variance of incidence of bilateral LADI asymmetry in different age groups, Pearson-test (2-tailed) is used to evaluate the correlation between VBLADI and rotary function of atlanto-axial joint, precise test of fourfold table is used to compare normal group with patient groups. Results: (1) In the normal control group: asymmetry of bilateral LADI were observed in 204 among 240 (85.00%) healthy volunteers including 60 youngsters ( 95% of ∣ VBLADI ∣ were 0.850 mm, 2.450 mm in the young ( 95% in the young and in the adult respectively. There was no correlation between VBLADI(-2.146 to 2.114 mm, Median 0.000 mm) and LA (22.949° to 44.649°, Median 34.500°), RA (25.284° to 45.334°, Median 35.300°), VLRA (-11.643° to 8.623°, median 0.000°) respectively in normal people (r=-0.030, -0.005, 0.026, P>0.05). (2) In the study with 32 patients including 25 youngsters ( 95% in group AALSD and group AACD than in abnormal group (P<0.01), but there is no difference between group AARD and normal group (P=0.738). Conclusion: The imaging finding of 'asymmetry of bilateral LADI' may be either a physiological variation or a pathological condition, clinical manifestations and other imaging findings should be evaluated to make a diagnosis. (authors)

Retrospctive studies of small ruminant diseases diagnosed at the ...

African Journals Online (AJOL)

Retrospctive studies of small ruminant diseases diagnosed at the Veterinary Teaching Hospital, University of Agriculture, Makurdi, Nigeria. J.W. Jatfa, A.Y. Adenkola, I Victor, A Kisani, S.S. Adamu, P.A. Onyeyili ...

The evaluation of the diet/disease relation in the EPIC study: considerations for the calibration and the disease models

DEFF Research Database (Denmark)

Ferrari, Pietro; Day, Nicholas E; Boshuizen, Hendriek C

2008-01-01

BACKGROUND: International multicentre studies on diet and cancer are relatively new in epidemiological research. They offer a series of challenging methodological issues for the evaluation of the association between dietary exposure and disease outcomes, which can both be quite heterogeneous acro...

IDIOPATHIC LARYN GEAL STENOSIS - A VERY RARE CASE

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Sudip Kumar; Ruma; Rajesh; Arvind Kumar; Subhendu

2014-01-01

A 35 year old lady presented in the Out Patient Department with cough , dyspnea and gradual hoarseness for last 5 years. After proper history taking and thorough clinical examination , diagnosis of Laryngeal Stenosis was made. Subsequently by excluding important causes of Laryngeal Stenosis like trauma , chronic infection , tuberculosis and other granulomatous diseases , the diagnosis of Idiopathic Laryngeal Stenosis was established KEYWORDS ...

A Retrospective Study on Magnitude and Factors Associated with ...

African Journals Online (AJOL)

the problem of anemia in the postpartum period. Materials and Methods. Background. Mangalore is a coastal border district in the state of Karnataka with a total population of about 1.8 million. The Government. District Lady Goschen Hospital provides maternity services to not only the pregnant women of this district, but also ...

Prevalence of autoantibodies in the course of Gaucher disease type 1: A multicenter study comparing Gaucher disease patients to healthy subjects.

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Serratrice, Christine; Bensalah, Nesma; Penaranda, Guillaume; Bardin, Nathalie; Belmatoug, Nadia; Masseau, Agathe; Rose, Christian; Lidove, Olivier; Camou, Fabrice; Maillot, François; Leguy, Vanessa; Magy-Bertrand, Nadine; Marie, Isabelle; Cherin, Patrick; Bengherbia, Monia; Carballo, Sebastian; Boucraut, José; Serratrice, Jacques; Berger, Marc; Verrot, Denis

2018-01-01

Type 1 Gaucher disease may be related to the presence of autoantibodies. Their clinical significance is questioned. Primary endpoint was to compare the prevalence of autoantibodies in type 1 Gaucher disease patients with healthy subjects, seeking correlations with autoimmune characteristics. Secondary endpoints were to determine whether patients with autoantibodies reported autoimmunity-related symptoms and if genotype, splenectomy or treatment influenced autoantibodies presence. Type 1 Gaucher disease patients and healthy volunteers were included in this national multicenter exploratory study. Autoantibodies presence was compared in both groups and assessed regarding to genotype, splenectomy, Gaucher disease treatment and autoimmunity-related symptoms. Twenty healthy subjects and 40 type 1 Gaucher disease patients were included. Of the studied group: 15 patients undergone splenectomy, 37 were treated either with enzyme replacement therapy (34) or with substrate reduction therapy (3), 25 were homozygous/heterozygous for the N370S mutation. In type 1 Gaucher disease group (studied group), 52% had positive autoantibodies versus 26% in control group. Antiphospholipid antibodies were more frequent in the studied group (30% vs. 5%), but without correlation to thrombosis, osteonecrosis or bone infarcts. In the studied group, antinuclear antibodies were more frequent (25% vs. 16%). None of the patients with autoantibodies had clinical manifestations of autoimmune diseases. Autoantibodies were not correlated with treatment, genotype, or splenectomy, except for anticardiolipid, more frequent in splenectomized patients. In type 1 Gaucher disease, autoantibodies were more frequent compared to a healthy population. However, they were not associated with an increased prevalence of clinical active autoimmune diseases. Copyright © 2016 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

Incontinentia pigmenti--ophthalmological observation of a series of cases and review of the literature.

LENUS (Irish Health Repository)

O'Doherty, M

2012-02-01

AIM: The aims of this study were to make an inventory of the disease in Ireland, to acquire better knowledge of the relationship between genetic makeup and phenotypic ocular presentation and, finally, through literature review and personal experience, to establish clear guidelines on best practice in the management of children with this rare condition both in terms of screening and follow-up. METHODS: All patients who attended the dermatology and genetic clinic in Our Lady\\'s Hospital for Sick Children, Crumlin, with incontinentia pigmenti (IP) were contacted and invited to attend the eye clinic for ocular assessment. Children who were already attending the ophthalmic services before commencement of the study had their charts reviewed for assessment. RESULTS: 11 of 19 patients agreed to attend the clinic for ocular assessment. Of these patients, nine had genetic testing. The mean age of the patients at the examination was 8 years (3 months to 29 years). In 10 patients, IP was the result of a spontaneous mutation, whereas the condition was inherited from an affected mother in one patient. Of the 11 patients with IP, 5 have visually significant ocular findings (47%). We describe the case history of four of these children briefly to outline the severity of this condition. CONCLUSION: Our patients had a significant percentage of ocular abnormalities (47%). We have outlined an examination schedule for patients with and without retinal pathology and recommend fluorescein angiography in patients with retinal pathology to fully determine the extent of ischaemia. Like other studies, early treatment with peripheral retinal photocoagulation to reduce the risk of retinal detachment is recommended in this study.

Linguistic ability in early life and the neuropathology of Alzheimer's disease and cerebrovascular disease. Findings from the Nun Study.

Science.gov (United States)

Snowdon, D A; Greiner, L H; Markesbery, W R

2000-04-01

Findings from the Nun Study indicate that low linguistic ability in early life has a strong association with dementia and premature death in late life. In the present study, we investigated the relationship of linguistic ability in early life to the neuropathology of Alzheimer's disease and cerebrovascular disease. The analyses were done on a subset of 74 participants in the Nun Study for whom we had handwritten autobiographies completed some time between the ages of 19 and 37 (mean = 23 years). An average of 62 years after writing the autobiographies, when the participants were 78 to 97 years old, they died and their brains were removed for our neuropathologic studies. Linguistic ability in early life was measured by the idea (proposition) density of the autobiographies, i.e., a standard measure of the content of ideas in text samples. Idea density scores from early life had strong inverse correlations with the severity of Alzheimer's disease pathology in the neocortex: Correlations between idea density scores and neurofibrillary tangle counts were -0.59 for the frontal lobe, -0.48 for the temporal lobe, and -0.49 for the parietal lobe (all p values < 0.0001). Idea density scores were unrelated to the severity of atherosclerosis of the major arteries at the base of the brain and to the presence of lacunar and large brain infarcts. Low linguistic ability in early life may reflect suboptimal neurological and cognitive development, which might increase susceptibility to the development of Alzheimer's disease pathology in late life.

Role of bacteria in leukocyte adhesion deficiency-associated periodontitis.

Science.gov (United States)

Hajishengallis, George; Moutsopoulos, Niki M

2016-05-01

Leukocyte adhesion deficiency Type I (LAD-I)-associated periodontitis is an aggressive form of inflammatory bone loss that has been historically attributed to lack of neutrophil surveillance of the periodontal infection. However, this form of periodontitis has proven unresponsive to antibiotics and/or mechanical removal of the tooth-associated biofilm. Recent studies in LAD-I patients and relevant animal models have shown that the fundamental cause of LAD-I periodontitis involves dysregulation of a granulopoietic cytokine cascade. This cascade includes interleukin IL-23 (IL-23) and IL-17 that drive inflammatory bone loss in LAD-I patients and animal models and, moreover, foster a nutritionally favorable environment for bacterial growth and development of a compositionally unique microbiome. Although the lack of neutrophil surveillance in the periodontal pockets might be expected to lead to uncontrolled bacterial invasion of the underlying connective tissue, microbiological analyses of gingival biopsies from LAD-I patients did not reveal tissue-invasive infection. However, bacterial lipopolysaccharide was shown to translocate into the lesions of LAD-I periodontitis. It is concluded that the bacteria serve as initial triggers for local immunopathology through translocation of bacterial products into the underlying tissues where they unleash the dysregulated IL-23-IL-17 axis. Subsequently, the IL-23/IL-17 inflammatory response sustains and shapes a unique local microbiome which, in turn, can further exacerbate inflammation and bone loss in the susceptible host. Copyright © 2015 Elsevier Ltd. All rights reserved.

Comparative Study on the Long-Acting Thyroid Stimulator in Graves' Disease

International Nuclear Information System (INIS)

Kim, Dong Sup; Koh, Chang Soon; Lee, Mun Ho

1973-01-01

In order to study the role of LATS in the pathogenesis of the Graves' disease, the serum activity of the LATS was determined by the bioassay of the modified McKenzie method. The subjects examined in the study consisted of 76 individuals including 12 cases of normal control, 54 cases with typical Graves' disease and 10 cases of chronic thyroiditis. The data observed in the patients with the Graves' disease were analyzed in comparison with the clinical features, laboratory findings, and responsiveness to the treatment. The results obtained are as follows: 1) None of the subjects which did not have the Graves' disease showed a positive LATS activity, except one case with the chronic thyroiditis. 2) Twenty-two oui of the 54 cases with the Graves' disease showed positive results for LATS (40.7%). The positivity was significantly higher in the patients who had been treated with antithyroid regimen but still showed hyperthyroidism than in the patients who had not been treated. 3) The activity of LATS was gradually decreased or even became absent as the hyperthyroidism was corrected after the treatment. 4) No significant difference was noticed in age and-sex between the positive and negative groups of LATS. 5) There was no evidence of significant correlation between the LATS activity and clinical features.

A statistical study of the maxillofacial diseases by radiograms

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Chung, Yoo Tai; Lee, Sang Chull [College of Dentistry, Kyunghee University, Seoul (Korea, Republic of)

1974-11-15

This report based on 300 cases of serious diseases in maxillofacial region by radiograms seen at the department of dental radiodontics, infirmary school of dentistry, Kyung Hee University from October 1971 to August 1974. The maxillofacial diseases were analysed upon the following items, such as 1) the frequency of dominant diseases, 2) sex-ratio of male to female, 3) predominant region of diseases, 4) comparison with the age, 5) the incidence of diseases in relative to the individual teeth. The results were obtained as follows. 1) Among the total of 300 cases of the patients, the frequency of dominant diseases of patients were fractures of facial bone (44.3 {+-} 2.87%), inflammatory diseases (22.7 {+-} 2.39%), cysts (11.1 {+-} 1.62%), tumors(10.7 {+-} 1.77%), maxillary sinusitis (7.9 {+-} 1.56%), temporomandibular joint disorders(3.3 {+-} 1.05%) in the order. 2) The sex ratio of male to female in occurrence of jaw fractures were 7.3 : 1, temporomandibular joint disorders were 2.1 : 1, inflammatory diseases were 1.8:1, maxillary sinusitis were 1.7 : 1, but tumors were 1: 1, while cysts were 1:1 .2 in sex difference.3) The predominant region of mandibular fractures were symphysis (17.3 {+-} 3.27%), canine region (15.0 {+-} 3.09%), and angle region(14.3 {+-} 3.04%) in the order. Inflammatory diseases were occurred frequently in mandible and it's left side were a little dominant. Odontogenic cysts were observed frequently in maxilla, but regardless of right and left. Carcinomas were involved most frequently in maxilla, while sarcomas and ameloblastomas in mandible. Frequency of the maxillary sinusitis w ere dominant in right side and molar area, also temporomandibular joint disorders were dominant in right side. 4) To study comparing with the age, jaw fractures showed the highest ratio at the 2nd decade (32.3 {+-} 4.06%), and 3rd decade (27.8 {+-} 3.89%), 4th decade (19.6 {+-} 3.44%), 6th decade (9.0 {+-} 2.47%), 5th decade(6.0 {+-} 2.06%), lst decade(5.3 {+-} 1

The impact of skin diseases on quality of life: A multicenter study.

Science.gov (United States)

Sanclemente, G; Burgos, C; Nova, J; Hernández, F; González, C; Reyes, M I; Córdoba, N; Arévalo, Á; Meléndez, E; Colmenares, J; Ariza, S; Hernández, G

2017-04-01

To date, no formal study has been published regarding how Colombian patients with skin disorders could be affected according to their perception of disease. To determine the impact in quality of life of skin diseases in a Colombian population. This multicenter study included patients with skin disease from almost the whole country. Individuals >18 years old; of any gender; with any skin disease and who signed informed consent, were included. We applied the Colombian validated version of the Skindex-29 instrument. A total of 1896 questionnaires had sufficient information for the analyses. No significant differences in sociodemographic characteristics of patients who returned the questionnaire incomplete vs. complete, were found. Participants mean age was 41.5 years. There were no statistical differences in men vs. women regarding the global (p=0.37), symptoms (p=0.71) and emotions (p=0.32) domains, whereas statistical differences were found in the function domain (p=0.04; Mann-Whitney U test). Psoriasis, contact dermatitis, atopic dermatitis, urticaria, hair disorders, Hansen's disease, scars, hyperhidrosis and genital human papillomavirus disease scored the highest. Skindex-29 score variability as a result of differences in the location of the skin lesions, their inflammatory or non-inflammatory nature, and the start of therapy. Even the most localized or asymptomatic skin lesion in our population leads to a disruption at some level of patient's wellness. This study adds well supported scientific data of the burden of skin diseases worldwide. Copyright © 2016 AEDV. Publicado por Elsevier España, S.L.U. All rights reserved.

Does pregnancy change the disease course? A study in a European cohort of patients with inflammatory bowel disease

DEFF Research Database (Denmark)

Riis, L; Vind, Ida; Politi, P

2006-01-01

BACKGROUND AND AIMS: Inflammatory bowel disease (IBD) often affects patients in their fertile age. The aim of this study was to describe pregnancy outcome in a European cohort of IBD patients. As data are limited regarding the effect of pregnancy on disease course, our second objective was to inv...

Forecasting and Analyzing the Disease Burden of Aged Population in China, Based on the 2010 Global Burden of Disease Study

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Chengzhen Bao

2015-06-01

Full Text Available Background: Forecasting the disease burden of the elderly will contribute to make a comprehensive assessment about physical and mental status of the elderly in China and provide a basis for reducing the negative consequences of aging society to a minimum. Methods: This study collected data from a public database online provided by Global Burden of Disease Study 2010. Grey model GM (1, 1 was used to forecast all-cause and disease-specific rates of disability adjusted life years (DALYs in 2015 and 2020. Results: After cross-sectional and longitudinal analysis, we found that non-communicable diseases (NCDs were still the greatest threats in the elderly, followed by injuries. As for 136 predicted causes, more than half of NCDs increased obviously with age, less than a quarter of communicable, material, neonatal, and nutritional disorders or injuries had uptrend. Conclusions: The findings display the health condition of the Chinese elderly in the future, which will provide critical information for scientific and sociological researches on preventing and reducing the risks of aging society.

An epidemiological study of the association of coffee with chronic liver disease.

Science.gov (United States)

Walton, H B; Masterton, G S; Hayes, P C

2013-11-01

Chronic liver disease affects 855 people per million in the UK. Previous studies have reported that coffee appears protective against the development of abnormal liver enzymes, hepatic fibrosis and cirrhosis. The aim of this study, the first in a Scottish population, was to compare coffee consumption in patients with liver disease and that of control populations to determine correlations between coffee intake and the incidence of non-cancerous liver disease and with Child's-Pugh and model for end-stage liver disease (MELD) scores. Two hundred and eighty-six patients attending the liver outpatient department at the Royal Infirmary of Edinburgh completed a questionnaire regarding coffee consumption and lifestyle factors. Control questionnaires were also completed by 100 orthopaedic outpatients and 120 medical students. Patients with cirrhosis (n = 95) drank significantly less coffee than those without cirrhosis (p = coffee consumption. Coffee drinking is associated with a reduced prevalence of cirrhosis in patients with chronic liver disease. However, there was no significant difference in the amount of coffee drunk by liver patients and the control groups. It is possible that by changing the amount of coffee drunk, the development of cirrhosis in liver disease could be postponed.

Beyond disease susceptibility-Leveraging genome-wide association studies for new insights into complex disease biology.

Science.gov (United States)

Lee, J C

2017-12-01

Genetic studies in complex diseases have been highly successful, but have also been largely one-dimensional: predominantly focusing on the genetic contribution to disease susceptibility. While this is undoubtedly important-indeed it is a pre-requisite for understanding the mechanisms underlying disease development-there are many other important aspects of disease biology that have received comparatively little attention. In this review, I will discuss how existing genetic data can be leveraged to provide new insights into other aspects of disease biology, why such insights could change the way we think about complex disease, and how this could provide opportunities for better therapies and/or facilitate personalised medicine. To do this, I will use the example of Crohn's disease-a chronic form of inflammatory bowel disease that has been one of the main success stories in complex disease genetics. Indeed, thanks to genetic studies, we now have a much more detailed understanding of the processes involved in Crohn's disease development, but still know relatively little about what determines the subsequent disease course (prognosis) and why this differs so considerably between individuals. I will discuss how we came to realise that genetic variation plays an important role in determining disease prognosis and how this has changed the way we think about Crohn's disease genetics. This will illustrate how phenotypic data can be used to leverage new insights from genetic data and will provide a broadly applicable framework that could yield new insights into the biology of multiple diseases. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

The Videofluorographic Swallowing Study in Rheumatologic Diseases: A Comprehensive Review

Science.gov (United States)

Di Piazza, Ambra; Costanzo, Massimo; Scopelliti, Laura; Salvaggi, Francesco; Cupido, Francesco; Salerno, Sergio; Lo Casto, Antonio; Midiri, Massimo; Lo Re, Giuseppe; Lagalla, Roberto

2017-01-01

Autoimmune connective tissue diseases are a heterogeneous group of pathologies that affect about 10% of world population with chronic evolution in 20%–80%. Inflammation in autoimmune diseases may lead to serious damage to other organs including the gastrointestinal tract. Gastrointestinal tract involvement in these patients may also due to both a direct action of antibodies against organs and pharmacological therapies. Dysphagia is one of the most important symptom, and it is caused by failure of the swallowing function and may lead to aspiration pneumonia, malnutrition, dehydration, weight loss, and airway obstruction. The videofluorographic swallowing study is a key diagnostic tool in the detection of swallowing disorders, allowing to make an early diagnosis and to reduce the risk of gastrointestinal and pulmonary complications. This technique helps to identify both functional and structural anomalies of the anatomic chain involved in swallowing function. The aim of this review is to systematically analyze the basis of the pathological involvement of the swallowing function for each rheumatological disease and to show the main features of the videofluorographic study that may be encountered in these patients. PMID:28706536

Metastatic tumours to hypophysis: a report of three cases and review of literature

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Tomaž Šmigoc

2016-10-01

Full Text Available Background. Metastatic tumours to pituitary are rare. The most frequent are metastases from breast and lung.Methods. In this paper, three cases of metastatic tumours to the pituitary are presented with panhypopituitarism as a common symptom: I a 60-year-old gentleman with metastasis of diffuse large B cell lymphoma, who presented with diabetes insipidus, II a 54-year-old lady with metastatic renal clear cell carcinoma and consequent disturbances in visual acuity, brain nerve paresis and III a 57-year-old lady with breast cancer metastasis, visual impairment and brain nerve paresis.Results. A transnasal endoscopic resection of the tumours was performed in all cases, followed by oncological treatment. All patients improved after the treatment.Conclusions. Despite the rarity of the disease, a metastatic tumour to the pituitary gland must be included in the differential diagnosis when symptoms such as diabetes insipidus, ophthalmoplegy due to brain nerve palsies, rapid course of the disease and headache are observed. In 20% to 30%, pituitary metastases are the first manifestation of a tumour of unknown origin. Surgical and adjuvant therapy may improve the quality of life. The survival and prognosis are generally poor.

“Gestaltomics”: Systems Biology Schemes for the Study of Neuropsychiatric Diseases

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Nora A. Gutierrez Najera

2017-05-01

Full Text Available The integration of different sources of biological information about what defines a behavioral phenotype is difficult to unify in an entity that reflects the arithmetic sum of its individual parts. In this sense, the challenge of Systems Biology for understanding the “psychiatric phenotype” is to provide an improved vision of the shape of the phenotype as it is visualized by “Gestalt” psychology, whose fundamental axiom is that the observed phenotype (behavior or mental disorder will be the result of the integrative composition of every part. Therefore, we propose the term “Gestaltomics” as a term from Systems Biology to integrate data coming from different sources of information (such as the genome, transcriptome, proteome, epigenome, metabolome, phenome, and microbiome. In addition to this biological complexity, the mind is integrated through multiple brain functions that receive and process complex information through channels and perception networks (i.e., sight, ear, smell, memory, and attention that in turn are programmed by genes and influenced by environmental processes (epigenetic. Today, the approach of medical research in human diseases is to isolate one disease for study; however, the presence of an additional disease (co-morbidity or more than one disease (multimorbidity adds complexity to the study of these conditions. This review will present the challenge of integrating psychiatric disorders at different levels of information (Gestaltomics. The implications of increasing the level of complexity, for example, studying the co-morbidity with another disease such as cancer, will also be discussed.

Comparison of effect of locally available brands of clopidogrel on platelet aggregation in patients with coronary disease

International Nuclear Information System (INIS)

Khan, S.B.; Hameedullah; Noor, L.; Awan, Z.A.; Din, S.U.; Muhammad Hafeezullah, M.

2010-01-01

Background: Anticoagulant effect of clopidogrel is of utmost importance in coronary artery disease, especially in prevention of coronary stent thrombosis. Recently, many new local brands of clopidogrel have been launched, with unknown efficacy. This study was conducted with the aim to compare two locally prepared clopidogrel brands, in terms of the effect of a loading dose of 600 mg on inhibition of platelet aggregation in patients with coronary artery disease. Methods: This was a double blind randomised study. Sample population consisting of 35 patients, were admitted at Lady Reading Hospital, Peshawar, for the management of coronary artery disease. Baseline platelet aggregation of all these patients was measured. These patients were divided in two groups randomly. Group-A consisting of 18 patients was given brand 'A' clopidogrel 600 mg, while Group-B consisting of 17 patients was give brand 'B' of clopidogrel 600 mg. The platelet aggregation of both groups was then measured at baseline, and at 2, 4, and 6 hours after taking the loading dose of 600 mg. Results: Platelet aggregation time at baseline in Group-A was 2.61+- 2.28 sec. and in Group-B it was 2.24 +- 1.52 sec. (p=0.57). After 2 hours of clopidogrel administration in Group-A the platelet aggregation time was 1.44 +- 1.58 sec. and in Group-B it was 1.53 +- 1.107 sec. (p=0.85). Platelet aggregation time after 4 hours in Group-A was 0.28 +- 0.57 sec. and in Group-B 1.06 +- 1.03 sec. (p=0.009), and after 6 hours it was 0.00 +- 0.00 sec. in Group-A and in Group-B it was 0.59 +- 0.71 sec. (p=0.001). Conclusion: The two brands of clopidogrel had a significant difference in their effect on inhibition of platelet aggregation. Different brands of clopidogrel may not be equally effective. (author)

[The French Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort study: To better understand chronic kidney disease].

Science.gov (United States)

Stengel, Bénédicte; Combe, Christian; Jacquelinet, Christian; Briançon, Serge; Fouque, Denis; Laville, Maurice; Frimat, Luc; Pascal, Christophe; Herpe, Yves-Édouard; Morel, Pascal; Deleuze, Jean-François; Schanstra, Joost P; Pisoni, Ron L; Robinson, Bruce M; Massy, Ziad A

2016-04-01

Preserving kidney function and improving the transition from chronic kidney disease to end stage is a research and healthcare challenge. The national Chronic Kidney Disease-Renal Epidemiology and Information Network (CKD-REIN) cohort was established to identify the determinants, biomarkers and practice patterns associated with chronic kidney disease outcomes. The study will include more than 3000 adult patients with moderate to advanced chronic kidney disease from a representative sample of 40 nephrology clinics with respect to regions and legal status, public or private. Patients are recruited during a routine visit and followed for 5 years, before and after starting renal replacement therapy. Patient-level clinical, biological, and lifestyle data are collected annually, as well as provider-level data on clinical practices, coordinated with the International Chronic Kidney Disease Outcomes and Practice Pattern Study. Blood and urine samples are stored in a biobank. Major studied outcomes include survival, patient-reported outcomes, disease progression and hospitalizations. More than 13,000 eligible patients with chronic kidney disease were identified, 60% with stage 3 and 40% with stage 4. Their median age is 72 years [interquartile range, 62-80 years], 60% are men and 38% have diabetes. By the end of December 2015, 2885 patients were included. The CKD-REIN cohort will serve to improve our understanding of chronic kidney disease and provide evidence to improve patient survival and quality of life as well as health care system performances. Copyright © 2016 Association Société de néphrologie. All rights reserved.

Gastroesophageal Reflux Disease: A Population Based Study

OpenAIRE

Nwokediuko, Sylvester

2009-01-01

Background The prevalence of gastroesophageal reflux disease varies in different parts of the world. There are no population based studies in Nigeria. The main objectives of this study were to determine the prevalence and risk factors for gastroesophageal reflux disease in a population of Nigerian medical students. Methods The Carlsson-Dent questionnaire was administered to medical students in the clinical phase of their training at the University of Nigeria, Enugu Campus. Some putative risk ...

The contribution of twin studies to the understanding of the aetiology of asthma and atopic diseases

DEFF Research Database (Denmark)

Thomsen, Simon F

2015-01-01

The prevalence of asthma and other atopic diseases has increased markedly during the past decades and the reasons for this are not fully understood. Asthma is still increasing in many parts of the world, notably in developing countries, and this emphasizes the importance of continuing research...... aimed at studying the aetiological factors of the disease and the causes of its increase in prevalence. Twin studies enable investigations into the genetic and environmental causes of individual variation in multifactorial diseases such as asthma. Thorough insight into these causes is important...... as this will ultimately guide the development of preventive strategies and targeted therapies. This review explores the contribution of twin studies to the understanding of the aetiology of asthma and atopic diseases....

Neutropenia, neutrophil dysfunction, and inflammatory bowel disease in glycogen storage disease type Ib : Results of the European Study on Glycogen Storage Disease Type I

NARCIS (Netherlands)

Visser, G; Rake, JP; Fernandes, J; Labrune, P; Leonard, JV; Moses, S; Ullrich, K; Smit, GPA

Objective: To investigate the incidence, the severity, and the course of neutropenia, neutrophil dysfunction, and inflammatory bowel disease (IBD) in glycogen storage disease (GSD) type Ib. Method: As part of a collaborative European Study on GSD type I, a retrospective registry was established in

Study on clinical symptoms in canine cardiac diseases

Directory of Open Access Journals (Sweden)

F. Karlette Anne

Full Text Available Cardiac diseases in canines are an extensively studied phenomenon all over the world but meagre information has been reported in India. Certain problems, including historical, physical, and laboratory abnormalities, are associated with cardiovascular or pulmonary disease. In India however, the recognition of canine cardiac diseases has been delayed, and ignored on account of lack of awareness and knowledge by the owner and inadequate diagnostic facility to a field veterinarian. Considering the above facts, the present study was undertaken in Gujarat to survey the prevalence of common cardiac diseases in hospital population of dogs along with the clinical symptoms which often goes undetected due to lack of proper diagnostic techniques to be implied and the most forms of heart disease may be present for many years before any evidence of failure develops. In the present study most of the clinical cases of cardiac diseases were presented with a history of nocturnal coughing (seven cases; 2.55%, exercise intolerance (five cases; 1.82%, partial or complete anorexia (five cases; 1.82%, swelling in abdominal area (four cases; 1.45%, dullness and depression (two cases; 0.72%, cachexia and hepatojugular pulsation (one case each; 0.36% each at times. [Vet World 2009; 2(8.000: 307-309

Screening Fabry's disease in chronic kidney disease patients not on dialysis: a multicenter study.

Science.gov (United States)

Yeniçerioğlu, Yavuz; Akdam, Hakan; Dursun, Belda; Alp, Alper; Sağlam Eyiler, Funda; Akın, Davut; Gün, Yelda; Hüddam, Bülent; Batmazoğlu, Mehmet; Gibyeli Genek, Dilek; Pirinççi, Serhat; Ersoy, İsmail Rıfkı; Üzüm, Atilla; Soypaçacı, Zeki; Tanrısev, Mehmet; Çolak, Hülya; Demiral Sezer, Sibel; Bozkurt, Gökay; Akyıldız, Utku Oğan; Akyüz Ünsal, Ayşe İpek; Ünübol, Mustafa; Uslu, Meltem; Eryılmaz, Ufuk; Günel, Ceren; Meteoğlu, İbrahim; Yavaşoğlu, İrfan; Ünsal, Alparslan; Akar, Harun; Okyay, Pınar

2017-11-01

Fabry's disease is an X-linked inherited, rare, progressive, lysosomal storage disorder, affecting multiple organs due to the deficient activity of α-galactosidase A (α-Gal A) enzyme. The prevalence has been reported to be 0.15-1% in hemodialysis patients; however, the information on the prevalence in chronic kidney disease not on dialysis is lacking. This study aimed to determine the prevalence of Fabry's disease in chronic kidney disease. The patients older than 18 years, enclosing KDIGO 2012 chronic kidney disease definitions, not on dialysis, were enrolled. Dried blood spots on Guthrie papers were used to analyze α-Gal A enzyme and genetic analysis was performed in individuals with enzyme activity ≤1.2 μmol/L/h. A total of 1453 chronic kidney disease patients not on dialysis from seven clinics in Turkey were screened. The mean age of the study population was 59.3 ± 15.9 years. 45.6% of patients were female. The creatinine clearance of 77.3% of patients was below 60 mL/min/1.73 m 2 , 8.4% had proteinuria, and 2.5% had isolated microscopic hematuria. The mean value of patients' α-Gal A enzyme was detected as 2.93 ± 1.92 μmol/L/h. 152 patients had low levels of α-Gal A enzyme activity (≤1.2 μmol/L/h). In mutation analysis, A143T and D313Y variants were disclosed in three male patients. The prevalence of Fabry's disease in chronic kidney disease not on dialysis was found to be 0.2% (0.4% in male, 0.0% in female). Fabry's disease should be considered in the differential diagnosis of chronic kidney disease with unknown etiology even in the absence of symptoms and signs suggestive of Fabry's disease.

Retrospective Study of Epidermal Parasitic Skin Diseases amongst ...

African Journals Online (AJOL)

ADOWIE PERE

ABSTRACT: A ten year retrospective study (1997-2006) was undertaken to determine the prevalence of. Epidermal Parasitic Skin Diseases (EPSD) among out-patients from the skin diseases hospital in Maiduguri, Borno state. Out of 10,000 out-patients examined during the study period, 3527(35.27%) where infected with ...

Where to prick the apple for skin testing?

Science.gov (United States)

Vlieg-Boerstra, B J; van de Weg, W E; van der Heide, S; Dubois, A E J

2013-09-01

Mal d 1 is not equally distributed over the apple. We aimed to examine the influence of the location of pricking in the apple on prick-to-prick skin prick test (PTP) results. PTPs were performed in autumn 2007 and spring 2008, before the birch pollen season, in 32 Dutch adults with symptoms of oral allergy to fresh apple, using apples harvested in autumn 2007. PTPs with fresh intact and unpeeled Pink Lady, Golden Delicious, Elise, Santana and Modi apples were performed using material obtained from approximately 2 cm near the stalk (top), and the middle region. All PTP responses were greater when performed with apple material near the stalk than from the middle region. In 2007, these differences were statistically significant for Pink Lady, Golden Delicious and Elise, and in 2008, for Pink Lady and Modi. When performing PTPs, the apple should be pricked near the stalk rather than in the middle. © 2013 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Natural history of severe atheromatous disease of the thoracic aorta: a transesophageal echocardiographic study.

Science.gov (United States)

Montgomery, D H; Ververis, J J; McGorisk, G; Frohwein, S; Martin, R P; Taylor, W R

1996-01-01

This study sought to prospectively observe the morphologic and clinical natural history of severe atherosclerotic disease of the thoracic aorta as defined by transesophageal echocardiography. Atherosclerosis of the thoracic aorta has been shown to be highly associated with risk for embolic events in transesophageal studies, but the natural history of the disease under clinical conditions has not been reported. During a 20-month period, 191 of 264 patients undergoing transesophageal echocardiography had adequate visualization of the aorta to allow atherosclerotic severity to be graded as follows: grade I = normal (44 patients); grade II = intimal thickening (52 patients); grade III = atheroma or = 5 mm (19 patients); grade V = mobile lesion (14 patients). All available patients with grades IV (8 patients) and V (10 patients) disease as well as a subgroup of 12 patients with grade III disease had follow-up transesophageal echocardiographic studies (mean [+/- SD] 11.7 +/- 0.9 months, range 6 to 22). Of 30 patients undergoing follow-up transesophageal echocardiographic studies, 20 (66%) had no change in atherosclerotic severity grade. Of the remaining 10 patients, atherosclerotic severity progressed one grade in 7 and decreased in 3 with resolved mobile lesions. Of 18 patients with grade IV or V disease of the aorta who underwent a follow-up study, 11 (61%) demonstrated formation of new mobile lesions. Of 10 patients with grade V disease on initial study who underwent follow-up study, 7 (70%) demonstrated resolution of a specific previously documented mobile lesion. However, seven patients (70%) with grade V disease also demonstrated development of a new mobile lesion. Of 33 patients with grade IV or V disease, 8 (24%) died during the study period, and 1 (3%) had a clinical embolic event. The presence of severe atherosclerotic disease of the thoracic aorta as defined by transesophageal echocardiography is associated with a high mortality rate. Although the morphologic

Epidemiology and the control of disease in China, with emphasis on the Chinese Biobank Study.

Science.gov (United States)

Li, L; Guo, Y; Chen, Z; Chen, J; Peto, R

2012-03-01

Similar to many other developing countries, China is facing a double burden of disease as a result of epidemiological transition. Non-communicable diseases (NCDs) represent a major challenge, having an adverse effect on the health of the Chinese population and increasing the economic burden of health care. In today's era of evidence-based medicine and decision making, China, as a developing country, has a lack of local scientific evidence which will affect the effectiveness of NCD prevention and control. As such, and on the basis of decades of cooperation and trust with the University of Oxford, the Chinese Biobank Study [Kadoorie Study of Chronic Disease in China (KSCDC)] was commenced in 2004. KSCDC, an international prospective project, aims to establish the basis of a blood-based health database, using genetic, environmental and lifestyle aspects to investigate and understand the causes, risk factors, pathogenesis, prevalence patterns and trends of major chronic diseases in China (such as stroke, coronary heart disease, cancer, diabetes, hypertension, chronic obstructive pulmonary disease etc.). This study has a duration of 15-20 years, and will provide scientific evidence for strategic planning of NCD prevention and control, and development of new treatment and intervention approaches. In total, approximately 510,000 adults aged 30-79 years have been recruited from the general population in 10 geographically defined regions (five rural and five urban) of China, with differing disease profiles and differing risk exposures. Extensive data collection has been undertaken with questionnaires, physical measurements, and collection and storage of blood samples. KSCDC is a multi-factor, multi-disease, multi-disciplinary large-scale chronic disease epidemiological study, and is also one of the largest long-term blood-based population cohort studies ever conducted in the world. It is worth mentioning that all gene specimens are kept in China, and all associated

Retrospective study on cattle and poultry diseases in Uganda

Directory of Open Access Journals (Sweden)

Joseph Byaruhanga

2017-12-01

Full Text Available Cattle and poultry enterprises are among the major contributors to food security and socioeconomic empowerment of households in Uganda. However, various diseases constrain their productivity. A two-year retrospective study between April 2012 and March 2014 was conducted using records for cattle and poultry diseases diagnosed at the Central Diagnostic Laboratory (CDL to determine prevalent diseases in Uganda. The laboratory received 836 samples from poultry (36.3% and cattle (63.7%. Of the 836 samples, 47.5% had a definitive diagnosis of disease causation. Most of the cattle and poultry diseases diagnosed were protozoan diseases (39.3% followed by bacterial (21.4%, viral (17.1%, helminthiasis (11.1%, nutritional diseases (4% and others (7.1%. For poultry, viral diseases (29.5% and protozoan diseases (27.1% especially newcastle disease (44.3% and coccidiosis (100% respectively, were the most diagnosed. While for cattle, hemo-protozoan parasites (52.1% were the most prevalent, of which 92.9% were east coast fever infection. Bacterial infection (20.5% in cattle were the second most diagnosed diseases and mastitis was the most diagnosed (46.2%. In summary, coccidioisis, collibacillosis, newcastle disease, gumboro disease, and avian helminthiasis were the most prevalent poultry diseases while in cattle, east coast fever, helminthiasis, mastitis, brucellosis and rabies were the most frequently diagnosed diseases. This study has identified the major diseases that hinder poultry and cattle production in Uganda. The data generated by CDL could be used for surveillance, monitoring and designing strategic interventions for control of poultry and cattle diseases in Uganda. Keywords: Coccidiosis, Collibacillosis, East coast fever, Mastitis, Newcastle disease, Rabies

Probiotics in diverticular disease of the colon: an open label study.

Science.gov (United States)

Lamiki, Pepu; Tsuchiya, Junji; Pathak, Surajit; Okura, Ruichi; Solimene, Umberto; Jain, Shalini; Kawakita, Shichiro; Marotta, Francesco

2010-03-01

To investigate the effectiveness and safety of a symbiotic mixture in preventing recurrence of constipation-related abdominal pain in patients with uncomplicated diverticular disease of the colon. Forty-six consecutive patients (10 men, 36 women, mean age 62.5 years, range 49 to 77 years), previously affected by symptomatic uncomplicated diverticular disease of the colon, were enrolled in a 6-month follow-up study in a prospective, randomized, open-label study. The following symptoms were assessed at entry and through follow-up by using a quantitative scale: constipation, diarrhoea and abdominal pain. After recruitment, the patients were assigned to the following treatment: SCM-III symbiotic mixture, 10 ml three times a day. The colonization of ingested Lactobacillus acidophilus 145 and Bifidobacterium spp. 420 was assessed by species-specific PCR. Forty-five patients completed the study (97%). Thirty-one patients (68%) were still symptom free after the 6th month of treatment. Treatment with SCM-III was regarded as "effective" or "very effective" in more than 78% of the patients altogether (pdiverticular disease of the colon, especially in those patients with constipation-predominant features.

Social media methods for studying rare diseases.

Science.gov (United States)

Schumacher, Kurt R; Stringer, Kathleen A; Donohue, Janet E; Yu, Sunkyung; Shaver, Ashley; Caruthers, Regine L; Zikmund-Fisher, Brian J; Fifer, Carlen; Goldberg, Caren; Russell, Mark W

2014-05-01

For pediatric rare diseases, the number of patients available to support traditional research methods is often inadequate. However, patients who have similar diseases cluster "virtually" online via social media. This study aimed to (1) determine whether patients who have the rare diseases Fontan-associated protein losing enteropathy (PLE) and plastic bronchitis (PB) would participate in online research, and (2) explore response patterns to examine social media's role in participation compared with other referral modalities. A novel, internet-based survey querying details of potential pathogenesis, course, and treatment of PLE and PB was created. The study was available online via web and Facebook portals for 1 year. Apart from 2 study-initiated posts on patient-run Facebook pages at the study initiation, all recruitment was driven by study respondents only. Response patterns and referral sources were tracked. A total of 671 respondents with a Fontan palliation completed a valid survey, including 76 who had PLE and 46 who had PB. Responses over time demonstrated periodic, marked increases as new online populations of Fontan patients were reached. Of the responses, 574 (86%) were from the United States and 97 (14%) were international. The leading referral sources were Facebook, internet forums, and traditional websites. Overall, social media outlets referred 84% of all responses, making it the dominant modality for recruiting the largest reported contemporary cohort of Fontan patients and patients who have PLE and PB. The methodology and response patterns from this study can be used to design research applications for other rare diseases. Copyright © 2014 by the American Academy of Pediatrics.

[Carotenoids: 2. Diseases and supplementation studies].

Science.gov (United States)

Faure, H; Fayol, V; Galabert, C; Grolier, P; Moël, G L; Stephens, J; Nabet, F

1999-05-01

Inverse correlations have been found in most studies on the relationship between dietary intake and plasma concentrations of carotenoids on one side and degenerative diseases such as cancer and cardiovascular diseases on the other side. Protective effects of carotenoids have been found for pathologies of the retina and the skin. Concentrations of these molecules in blood are lower in digestive pathologies and HIV. Short- and long-term toxicity of carotenoids was found to be low. In combination with the beneficial effects found for diets rich in carotenoids, this has initiated trials with relatively high doses of carotenoid supplements. In the study in Linxian (China) in a rural population with poor nutritional status, supplementation with beta-carotene, zinc, selenium and vitamin E lowered total mortality and mortality from stomach cancer. Other studies (ATBC, Caret.) on well-fed subjects did not show beneficial effects on mortality from cancer and cardiovascular diseases. On the contrary, higher mortality and lung cancer incidence was found in supplemented subjects that were also exposed to asbestos and cigarette smoke. In these studies, doses of supplemental beta-carotene were high and varied from 20 to 50 mg/day. One still ongoing study, called Suvimax, doses subjects for eight years with a cocktail of vitamins and minerals including 6 mg per day of beta-carotene. This supplementation with physiologically seen more "normal" doses might give clarity on the question if beta-carotene is the protective factor in fruits and vegetables.

A randomized study of the prevention of acute graft-versus-host disease

International Nuclear Information System (INIS)

Ramsay, N.K.C.; Kersey, J.H.; Robison, L.L.; McGlave, P.B.; Woods, W.G.; Krivit, W.; Kim, T.H.; Goldman, A.I.; Nesbit, M.E. Jr.

1982-01-01

Acute graft-versus-host disease is a major problem in allogeneic bone-marrow transplantation. We performed a randomized study to compare the effectiveness of two regimens in the prevention of acute graft-versus-host disease. Thirty-five patients received methotrexate alone, and 32 received methotrexate, antithymocyte globulin, and prednisone. Of the patients who received methotrexate alone, 48 percent had acute graft-versus-host disease, as compared with 21 per cent of those who received methotrexate, antithymocyte globulin, and prednisone (P = 0.01). The age of the recipient was a significant factor in the development of acute graft-versus-host disease: Older patients had a higher incidence of the disease (P = 0.001). We conclude that the combination of methotrexate, antithymocyte globulin, and prednisone significantly decreased the incidence of acute graft-versus-host disease and should be used to prevent this disorder in patients receiving allogeneic marrow transplants

Annual change in the rate of participation in breast cancer screening through active encouragement of sports participation. A survey of women participants at the annual meetings of the Pink Ribbon Ladies' Tennis Tournament organized by the Japan Women's Tennis Players' League

International Nuclear Information System (INIS)

Shimada, Naoko; Nozue; Etsuko; Fukuda, Mamoru; Sawai, Kiyoshi; Kasumi, Fujio

2007-01-01

In March 2002, an initial attempt was made to decrease breast cancer mortality by the Japan Society of Breast Health, by means of encouraging participation in sports. This was followed by other similar events. The present study was designed to examine whether these kinds of sport-associated events are actually effective for increasing the screening participation rate. We hoped that the results would reveal practical ways of organizing such programs. One of these activities, the All Japan Women's Tennis Players' League, has called for amateur players to participate in an annual meeting of the Pink Ribbon Ladies' Tennis Tournament since 2003. A survey of their knowledge about breast cancer and their will to participate in breast cancer screening has been carried out annually in 2003, 2004 and 2005, by asking the participants to respond to our questionnaires. As a result, the number of participants has increased: from 7,201 women in 2003, to 7,846 in 2004 and to 8,572 in 2005. The questionnaires included items about participation in breast cancer screening, performance of self-examination, and participation in mammography screening. The participation rate increased year by year. The participation rate at mammography screening was 21% in 2003, and this increased to 26% in 2005. Thus this kind of sports event appears to promote knowledge about breast cancer screening and to increase the participation rate. On the other hand, it was found that the rate of self-examination decreased from 53% to 22%. Therefore problems that need to be addressed in the future include not only increasing women's motivation to undergo screening, but also the selection of appropriate screening methods, their combination, and distribution of accurate information. (author)

Transgenic mice expressing human glucocerebrosidase variants: utility for the study of Gaucher disease.

Science.gov (United States)

Sanders, Angela; Hemmelgarn, Harmony; Melrose, Heather L; Hein, Leanne; Fuller, Maria; Clarke, Lorne A

2013-08-01

Gaucher disease is an autosomal recessively inherited storage disorder caused by deficiency of the lysosomal hydrolase, acid β-glucosidase. The disease manifestations seen in Gaucher patients are highly heterogeneous as is the responsiveness to therapy. The elucidation of the precise factors responsible for this heterogeneity has been challenging as the development of clinically relevant animal models of Gaucher disease has been problematic. Although numerous murine models for Gaucher disease have been described each has limitations in their specific utility. We describe here, transgenic murine models of Gaucher disease that will be particularly useful for the study of pharmacological chaperones. We have produced stable transgenic mouse strains that individually express wild type, N370S and L444P containing human acid β-glucosidase and show that each of these transgenic lines rescues the lethal phenotype characteristic of acid β-glucosidase null mice. Both the N370S and L444P transgenic models show early and progressive elevations of tissue sphingolipids with L444P mice developing progressive splenic Gaucher cell infiltration. We demonstrate the potential utility of these new transgenic models for the study of Gaucher disease pathogenesis. In addition, since these mice produce only human enzyme, they are particularly relevant for the study of pharmacological chaperones that are specifically targeted to human acid β-glucosidase and the common mutations underlying Gaucher disease. Copyright © 2013 Elsevier Inc. All rights reserved.

Innovative research methods for studying treatments for rare diseases: methodological review.

Science.gov (United States)

Gagne, Joshua J; Thompson, Lauren; O'Keefe, Kelly; Kesselheim, Aaron S

2014-11-24

To examine methods for generating evidence on health outcomes in patients with rare diseases. Methodological review of existing literature. PubMed, Embase, and Academic Search Premier searched for articles describing innovative approaches to randomized trial design and analysis methods and methods for conducting observational research in patients with rare diseases. We assessed information related to the proposed methods, the specific rare disease being studied, and outcomes from the application of the methods. We summarize methods with respect to their advantages in studying health outcomes in rare diseases and provide examples of their application. We identified 46 articles that proposed or described methods for studying patient health outcomes in rare diseases. Articles covered a wide range of rare diseases and most (72%) were published in 2008 or later. We identified 16 research strategies for studying rare disease. Innovative clinical trial methods minimize sample size requirements (n=4) and maximize the proportion of patients who receive active treatment (n=2), strategies crucial to studying small populations of patients with limited treatment choices. No studies describing unique methods for conducting observational studies in patients with rare diseases were identified. Though numerous studies apply unique clinical trial designs and considerations to assess patient health outcomes in rare diseases, less attention has been paid to innovative methods for studying rare diseases using observational data. © Gagne et al 2014.

Treatment of Crohn's disease with cannabis: an observational study.

Science.gov (United States)

Naftali, Timna; Lev, Lihi Bar; Yablecovitch, Doron; Yablekovitz, Doron; Half, Elisabeth; Konikoff, Fred M

2011-08-01

The marijuana plant cannabis is known to have therapeutic effects, including improvement of inflammatory processes. However, no report of patients using cannabis for Crohn's disease (CD) was ever published. To describe the effects of cannabis use in patients suffering from CD. In this retrospective observational study we examined disease activity, use of medication, need for surgery, and hospitalization before and after cannabis use in 30 patients (26 males) with CD. Disease activity was assessed by the Harvey Bradshaw index for Crohn's disease. Of the 30 patients 21 improved significantly after treatment with cannabis. The average Harvey Bradshaw index improved from 14 +/- 6.7 to 7 +/- 4.7 (P disease in humans. The results indicate that cannabis may have a positive effect on disease activity, as reflected by reduction in disease activity index and in the need for other drugs and surgery. Prospective placebo-controlled studies are warranted to fully evaluate the efficacy and side effects of cannabis in CD.

The chick eye in vision research: An excellent model for the study of ocular disease.

Science.gov (United States)

Wisely, C Ellis; Sayed, Javed A; Tamez, Heather; Zelinka, Chris; Abdel-Rahman, Mohamed H; Fischer, Andy J; Cebulla, Colleen M

2017-11-01

The domestic chicken, Gallus gallus, serves as an excellent model for the study of a wide range of ocular diseases and conditions. The purpose of this manuscript is to outline some anatomic, physiologic, and genetic features of this organism as a robust animal model for vision research, particularly for modeling human retinal disease. Advantages include a sequenced genome, a large eye, relative ease of handling and maintenance, and ready availability. Relevant similarities and differences to humans are highlighted for ocular structures as well as for general physiologic processes. Current research applications for various ocular diseases and conditions, including ocular imaging with spectral domain optical coherence tomography, are discussed. Several genetic and non-genetic ocular disease models are outlined, including for pathologic myopia, keratoconus, glaucoma, retinal detachment, retinal degeneration, ocular albinism, and ocular tumors. Finally, the use of stem cell technology to study the repair of damaged tissues in the chick eye is discussed. Overall, the chick model provides opportunities for high-throughput translational studies to more effectively prevent or treat blinding ocular diseases. Copyright © 2017 Elsevier Ltd. All rights reserved.

A Twin Study of Perthes Disease

DEFF Research Database (Denmark)

Metcalfe, David; Van Dijck, Stephanie; Parsons, Nicolas

2016-01-01

BACKGROUND: Legg-Calvé-Perthes disease (LCPD) is an idiopathic avascular necrosis of the femoral head. Its etiology is poorly understood, although previous studies have implicated low birth weight and possible genetic determinants. The aim of this study was to identify potential birth weight...

Circulatory disease mortality in the Massachusetts tuberculosis fluoroscopy cohort study

International Nuclear Information System (INIS)

Little, Mark P.; Zablotska, Lydia B.; Brenner, Alina V.; Lipshultz, Steven E.

2016-01-01

High-dose ionizing radiation is associated with circulatory disease. Risks from lower-dose fractionated exposures, such as from diagnostic radiation procedures, remain unclear. In this study we aimed to ascertain the relationship between fractionated low-to-medium dose radiation exposure and circulatory disease mortality in a cohort of 13,568 tuberculosis patients in Massachusetts, some with fluoroscopy screenings, between 1916 and 1961 and follow-up until the end of 2002. Analysis of mortality was in relation to cumulative thyroid (cerebrovascular) or lung (all other circulatory disease) radiation dose via Poisson regression. Over the full dose range, there was no overall radiation-related excess risk of death from circulatory disease (n = 3221; excess relative risk/Gy −0.023; 95 % CI −0.067, 0.028; p = 0.3574). Risk was somewhat elevated in hypertensive heart disease (n = 89; excess relative risk/Gy 0.357; 95 % CI −0.043, 1.030, p = 0.0907) and slightly decreased in ischemic heart disease (n = 1950; excess relative risk/Gy −0.077; 95 % CI −0.130, −0.012; p = 0.0211). However, under 0.5 Gy, there was a borderline significant increasing trend for all circulatory disease (excess relative risk/Gy 0.345; 95 % CI −0.032, 0.764; p = 0.0743) and for ischemic heart disease (excess relative risk/Gy 0.465; 95 % CI, −0.032, 1.034, p = 0.0682). Pneumolobectomy increased radiation–associated risk (excess relative risk/Gy 0.252; 95 % CI 0.024, 0.579). Fractionation of dose did not modify excess risk. In summary, we found no evidence of radiation-associated excess circulatory death risk overall, but there are indications of excess circulatory death risk at lower doses (<0.5 Gy). Although consistent with other radiation-exposed groups, the indications of higher risk at lower doses are unusual and should be confirmed against other data.