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Sample records for discovery problem luis

  1. 76 FR 10945 - San Luis Trust Bank, FSB, San Luis Obispo, CA; Notice of Appointment of Receiver

    Science.gov (United States)

    2011-02-28

    ... DEPARTMENT OF THE TREASURY Office of Thrift Supervision San Luis Trust Bank, FSB, San Luis Obispo, CA; Notice of Appointment of Receiver Notice is hereby given that, pursuant to the authority... appointed the Federal Deposit Insurance Corporation as sole Receiver for San Luis Trust Bank, FSB, San Luis...

  2. Effectiveness of discovery learning model on mathematical problem solving

    Science.gov (United States)

    Herdiana, Yunita; Wahyudin, Sispiyati, Ririn

    2017-08-01

    This research is aimed to describe the effectiveness of discovery learning model on mathematical problem solving. This research investigate the students' problem solving competency before and after learned by using discovery learning model. The population used in this research was student in grade VII in one of junior high school in West Bandung Regency. From nine classes, class VII B were randomly selected as the sample of experiment class, and class VII C as control class, which consist of 35 students every class. The method in this research was quasi experiment. The instrument in this research is pre-test, worksheet and post-test about problem solving of mathematics. Based on the research, it can be conclude that the qualification of problem solving competency of students who gets discovery learning model on level 80%, including in medium category and it show that discovery learning model effective to improve mathematical problem solving.

  3. Teresa y Luis, Luis y Teresa. Dos santos en tiempos recios

    Directory of Open Access Journals (Sweden)

    Emilio Callado Estela

    2016-06-01

    Full Text Available El presente artículo analiza la relación entre dos grandes santos españoles de la Contrarreforma Católica, Teresa de Jesús y el dominico fray Luis Bertrán. The present article analyses the relation between two big Spanish saints of the Catholic Counterreformation, Teresa de Jesus and the Dominican monk Luis Bertrán.

  4. Application of Cs-137 techniques to problems of sediment redistribution in Sungai Lui representative basin, Selangor, Malaysia (Part 1)

    International Nuclear Information System (INIS)

    Daud bin Mohamad.

    1982-11-01

    Since the beginning of the nuclear age, Cesium-137 has become a part of the world's ecosystems. Cs-137 is carried from the atmosphere to the ground by rainfall. On reaching the earth's surface, 137 Cs becomes strongly adsorbed to soil profiles and is concentrated predominantly in the surface layer, particularly in clayey soils. Systematic measurements of Cs-137 levels will therefore permit estimates to be made of the cumulative effects of soil redistribution over the past 25 years. Sediment movement in river catchments and coastal areas is a very old problem in Malaysia. In view of rapid development of urban and agricultural areas in Malaysia it was realised tha soil loss problems are particularly serious. The Sungai Lui catchment was chosen to be the investigational site. Geologically, the area comprises of granite and granitic schist. The area is mostly covered by forest (approx. 83%) and rubber (13%), padi (2%) and others (2%). The climate is considered to be typical of Peninsular Malaysia (equatorial) characterised by uniform temperature, high humidity and high rainfall. The area is mainly drained by the Lui River. Soil samples were collected from the catchment area at 4 sampling points in April 1981. The results of analyses of Cs-137 in soil samples from Sungai Lui catchment area ranged from 1.3 to 6.8 M Bq g -1 of sample and they could still be detected even up to 20 cm depth. A general pattern of Cs-137 distribution was observed in the soil profile at each site. The highest activity being in the top 3 cm layer and then decreasing up to about 6 cm. The activity increases again up to about 9 cm layer. From there onwards, it decreases. Based on these results, the estimated rate of sediment accumulation in the area was found to be about 0.47 cm/year. Since the samples were only collected from the depositional sites, further sampling especially from erosional site should therefore be carried out in order to obtain more complete data

  5. [Violence against women in transnational communities in San Luis Potosí, Mexico: a public health problem].

    Science.gov (United States)

    Flores, Yesica Yolanda Rangel

    2016-08-01

    Violence against women is a worldwide problem due to its impact on quality of life for those living under the complicity of a patriarchal culture and a state that makes such violence invisible. This article aims to give visibility to the contexts of violence affecting female "partners of migrants" in their places of origin, problematizing how such violence assaults their physical and mental health. This was a qualitative study with an interpretative anthropological focus, drawing on a sample of 21 women from rural and urban areas in San Luis Potosí, Mexico. Interviews were based on daily life history and discourse analysis. According to the results, women experience more violence when their spouses migrate, new forms of violence are committed against them, and the violence occurs in both the household and the community. Violence against women is a public health problem that should be treated through a framework that is sensitive to the social and cultural dynamics characterizing the contexts in which health programs are implemented.

  6. Luis Alvarez, the Hydrogen Bubble Chamber, Tritium, and Dinosaurs

    Science.gov (United States)

    Dinosaurs Resources with Additional Information * Patents Luis Alvarez Courtesy Lawrence Berkeley National JFK Assassination, and the End of the Dinosaurs Memorial Tribute for Luis W. Alvarez The Fruitful and Luis Alvarez (1911 - 1988) Why Dinosaurs Are Extinct Berkeley Scientists Report First Evidence that

  7. 33 CFR 110.120 - San Luis Obispo Bay, Calif.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false San Luis Obispo Bay, Calif. 110... ANCHORAGES ANCHORAGE REGULATIONS Special Anchorage Areas § 110.120 San Luis Obispo Bay, Calif. (a) Area A-1. Area A-1 is the water area bounded by the San Luis Obispo County wharf, the shoreline, a line drawn...

  8. 40 CFR 81.176 - San Luis Intrastate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 17 2010-07-01 2010-07-01 false San Luis Intrastate Air Quality Control Region. 81.176 Section 81.176 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED... Quality Control Regions § 81.176 San Luis Intrastate Air Quality Control Region. The San Luis Intrastate...

  9. Voice and Valency in San Luis Potosi Huasteco

    Science.gov (United States)

    Munoz Ledo Yanez, Veronica

    2014-01-01

    This thesis presents an analysis of the system of transitivity, voice and valency alternations in Huasteco of San Luis Potosi (Mayan) within a functional-typological framework. The study is based on spoken discourse and elicited data collected in the municipalities of Aquismon and Tancanhuitz de Santos in the state of San Luis Potosi, Mexico. The…

  10. Two combinatorial optimization problems for SNP discovery using base-specific cleavage and mass spectrometry.

    Science.gov (United States)

    Chen, Xin; Wu, Qiong; Sun, Ruimin; Zhang, Louxin

    2012-01-01

    The discovery of single-nucleotide polymorphisms (SNPs) has important implications in a variety of genetic studies on human diseases and biological functions. One valuable approach proposed for SNP discovery is based on base-specific cleavage and mass spectrometry. However, it is still very challenging to achieve the full potential of this SNP discovery approach. In this study, we formulate two new combinatorial optimization problems. While both problems are aimed at reconstructing the sample sequence that would attain the minimum number of SNPs, they search over different candidate sequence spaces. The first problem, denoted as SNP - MSP, limits its search to sequences whose in silico predicted mass spectra have all their signals contained in the measured mass spectra. In contrast, the second problem, denoted as SNP - MSQ, limits its search to sequences whose in silico predicted mass spectra instead contain all the signals of the measured mass spectra. We present an exact dynamic programming algorithm for solving the SNP - MSP problem and also show that the SNP - MSQ problem is NP-hard by a reduction from a restricted variation of the 3-partition problem. We believe that an efficient solution to either problem above could offer a seamless integration of information in four complementary base-specific cleavage reactions, thereby improving the capability of the underlying biotechnology for sensitive and accurate SNP discovery.

  11. 33 CFR 80.1130 - San Luis Obispo Bay, CA.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false San Luis Obispo Bay, CA. 80.1130 Section 80.1130 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY INTERNATIONAL NAVIGATION RULES COLREGS DEMARCATION LINES Pacific Coast § 80.1130 San Luis Obispo Bay, CA. A line drawn from...

  12. 76 FR 6517 - San Luis & Rio Grande Railroad-Petition for a Declaratory Order

    Science.gov (United States)

    2011-02-04

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35380] San Luis & Rio... petition filed by San Luis & Rio Grande Railroad (SLRG), the Board instituted a declaratory order... proposed operation of a truck-to-rail transload facility in Antonito, Colorado. See San Luis & Rio Grande R...

  13. Luis Alcoriza o la mexicanización del exiliado cinematográfico republicano = Luis Alcoriza or the Mexican Nationalization of the Republican Cinematography Exile

    Directory of Open Access Journals (Sweden)

    Jorge Chaumel Fernández

    2016-03-01

    Full Text Available Luis Alcoriza,  exiliado republicano español en México, desarrolló su carrera como  actor, guionista y director en su patria de adopción dándola algunas de sus mejores películas. En su condición de exiliado dispuso de mayor objetividad para mostrar los cambios de la sociedad mexicana y de sus principales problemas políticos. Figura imprescindible de la evolución del Cine Mexicano  de  la segunda mitad del siglo XX, se configura como uno de los principales ejemplos del  fenómeno de mexicanización de los cineastas exiliados.Luis Alcoriza, Spanish republican exile in Mexico, developed his career as an actor, writer and director in his adopted country giving her some of his best films. In his exile he had before as objective to show the changes in Mexican society and its major political problems. Essential figure in the evolution of Mexican cinema in the second half of the twentieth century stands as one of the prime examples of the phenomenon of mexicanización of exiled filmmakers.

  14. Keefektifan setting TPS dalam pendekatan discovery learning dan problem-based learning pada pembelajaran materi lingkaran SMP

    Directory of Open Access Journals (Sweden)

    Rahmi Hidayati

    2017-05-01

    The purpose of this study was to describe the effectiveness of setting Think Pair Share (TPS in the approach to discovery learning and problem-based learning in terms of student achievement, mathematical communication skills, and interpersonal skills of the student.  This study was a quasi-experimental study using the pretest-posttest nonequivalent group design. The research population comprised all Year VIII students of SMP Negeri 1 Yogyakarta. The research sample was randomly selected from eight classes, two classes were elected. The instrument used in this study is the learning achievement test, a test of mathematical communication skills, and interpersonal skills student questionnaires. To test the effectiveness of setting Think Pair Share (TPS in the approach to discovery learning and problem-based learning, the one sample t-test was carried out. Then, to investigate the difference in effectiveness between the setting Think Pair Share (TPS in the approach to discovery learning and problem-based learning, the Multivariate Analysis of Variance (MANOVA was carried out. The research findings indicate that the setting TPS discovery approach to learning and problem-based approach to learning (PBL is effective in terms of learning achievement, mathematical communication skills, and interpersonal skills of the students. No difference in effectiveness between setting TPS discovery approach to learning and problem-based learning (PBL in terms of learning achievement, mathematical communication skills, and interpersonal skills of the students. Keywords: TPS setting in discovery learning approach, in problem-based learning, academic achievement, mathematical communication skills, and interpersonal skills of the student

  15. GeoGebra Assist Discovery Learning Model for Problem Solving Ability and Attitude toward Mathematics

    Science.gov (United States)

    Murni, V.; Sariyasa, S.; Ardana, I. M.

    2017-09-01

    This study aims to describe the effet of GeoGebra utilization in the discovery learning model on mathematical problem solving ability and students’ attitude toward mathematics. This research was quasi experimental and post-test only control group design was used in this study. The population in this study was 181 of students. The sampling technique used was cluster random sampling, so the sample in this study was 120 students divided into 4 classes, 2 classes for the experimental class and 2 classes for the control class. Data were analyzed by using one way MANOVA. The results of data analysis showed that the utilization of GeoGebra in discovery learning can lead to solving problems and attitudes towards mathematics are better. This is because the presentation of problems using geogebra can assist students in identifying and solving problems and attracting students’ interest because geogebra provides an immediate response process to students. The results of the research are the utilization of geogebra in the discovery learning can be applied in learning and teaching wider subject matter, beside subject matter in this study.

  16. 75 FR 8735 - Endangered and Threatened Wildlife and Plants; Permit, San Luis Obispo County, CA

    Science.gov (United States)

    2010-02-25

    ...] Endangered and Threatened Wildlife and Plants; Permit, San Luis Obispo County, CA AGENCY: Fish and Wildlife... Luis Obispo County, California. We invite comments from the public on the application, which includes a... Luis Obispo County, California, that will meet Americans with Disabilities Act (ADA) accessibility...

  17. 75 FR 59285 - Endangered and Threatened Wildlife and Plants; Permit, San Luis Obispo County, CA

    Science.gov (United States)

    2010-09-27

    ...] Endangered and Threatened Wildlife and Plants; Permit, San Luis Obispo County, CA AGENCY: U.S. Fish and... project in the community of Los Osos, San Luis Obispo County, California. We invite comments from the... community of Los Osos, San Luis Obispo County, California. The parcel is legally described as Assessor...

  18. The effect of discovery learning and problem-based learning on middle school students’ self-regulated learning

    Science.gov (United States)

    Miatun, A.; Muntazhimah

    2018-01-01

    The aim of this research was to determine the effect of learning models on mathematics achievement viewed from student’s self-regulated learning. The learning model compared were discovery learning and problem-based learning. The population was all students at the grade VIII of Junior High School in Boyolali regency. The samples were students of SMPN 4 Boyolali, SMPN 6 Boyolali, and SMPN 4 Mojosongo. The instruments used were mathematics achievement tests and self-regulated learning questionnaire. The data were analyzed using unbalanced two-ways Anova. The conclusion was as follows: (1) discovery learning gives better achievement than problem-based learning. (2) Achievement of students who have high self-regulated learning was better than students who have medium and low self-regulated learning. (3) For discovery learning, achievement of students who have high self-regulated learning was better than students who have medium and low self-regulated learning. For problem-based learning, students who have high and medium self-regulated learning have the same achievement. (4) For students who have high self-regulated learning, discovery learning gives better achievement than problem-based learning. Students who have medium and low self-regulated learning, both learning models give the same achievement.

  19. Ontwikkeling en demonstratie van een geintegreerd bestrijdingssysteem voor de rode luis Myzus nicotianae

    NARCIS (Netherlands)

    Dijken, van M.J.

    1998-01-01

    De geïntegreerde plaagbestrijding van de paprikateelt onder glas, wordt sinds 1993 verstoord door de opkomst van de rode luis, Myzus nicotianae. Deze luis is namelijk resistent tegen het selectieve chemische correctiemiddel pirimicarb en een effectieve biologische bestrijding was onvoldoende

  20. Luis Carlos López

    Directory of Open Access Journals (Sweden)

    Rafael Maya

    1979-04-01

    Full Text Available Entre los poetasa del Centenario tuvo Luis Carlos López mucha popularidad en el extranjero, desde la publicación de su primer libro. Creo que su obra llamó la atención de filósofos como Unamuno y, si no estoy equivocado, Darío se refirió a ella en términos elogiosos. En Colombia ha sido encomiada hiperbólicamente por algunos, a tiemp que otros no le conceden mayor mérito.

  1. Hombres: Doctor Luis Ángel Arango

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1958-02-01

    Full Text Available En el documento se realiza la nota de conmemoración  del fallecimiento del Doctor Luis Ángel Arango  Esta nota tiene como fin realizar un homenaje a tan reputado ciudadano colombiano y mienbro de la comunidad de funcionarios del Banco de la República.

  2. Magnetotelluric data collected to characterize aquifers in the San Luis Basin, New Mexico

    Science.gov (United States)

    Ailes, Chad E.; Rodriguez, Brian D.

    2015-01-01

    The U.S. Geological Survey is conducting a series of multidisciplinary studies of the San Luis Basin as part of the Geologic Framework of Rio Grande Basins project. Detailed geologic mapping, high-resolution airborne magnetic surveys, gravity surveys, magnetotelluric surveys, and hydrologic and lithologic data are being used to better understand the aquifers in the San Luis Basin. This report describes one north-south and two east-west regional magnetotelluric sounding profiles, acquired in June of 2010 and July and August of 2011, across the San Luis Basin in northern New Mexico. No interpretation of the data is included.

  3. Ln3+ (Ln=Ce, Tb, Dy) and Hf doping of LuI3 powders – A material and spectroscopic study

    International Nuclear Information System (INIS)

    Wiatrowska, Aneta; Keur, Wilco; Ronda, Cees

    2016-01-01

    The moisture sensitivity of LuI 3 :Ce,Hf and luminescent properties of undoped LuI 3 and LuI 3 :M (M=Ce 3+ , Tb 3+ , Dy 3+ ) powders were investigated. The possibility of improving the air and moisture stability of LuI 3 :Ce by Hf doping was tested. It was proven that the Hf contribution to the LuI 3 :Ce stability is very limited and is insignificant to render LuI 3 :Ce scintillator powders suitable for applications. Photoluminescence results of LuI 3 without dopants added on purpose showed luminescence due to a plurality of rare-earth elements' impurities. Two types of self-trapped luminescence were found. Energy transfer between host lattice, self-trapped excitons and rare-earth ions was investigated.

  4. Fé antropológica como ponte entre fé e ideología em Juan Luis Segundo

    Directory of Open Access Journals (Sweden)

    Alvori Ahlert

    2007-01-01

    Full Text Available Este texto busca a compreensão da ideología em sua relação com a fé na teologia latinoamericana a partir da concepção de fé antropológica na obra de Juan Luis Segundo. Acreditamos que a questão da ideología, e sua relação com a fé, continua sendo urna questão atual no pensamento cristão, face aos velhos e novos problemas humanos que o novo sáculo vem apresentando. Concentramos nossa análise nos escritos de Juan Luis Segundo, um dos principáis representantes dessa teologia, por ser este teólogo que, ao nosso ver, mais trabalhou, de forma explícita, a questão da ideología e sua relação com a fé no contexto latinoamericanoThis text searchs the understanding of the ideology in its relation with the faith in the Latin American theology from the conception of antropology faith in the workmanship of Juan Luis Segundo. We believe that the question of the ideology, and its relation with the faith, continue being a current question in the Christian thought, face to the old and new human problems that the new century comes presenting. We concentrate our analysis on the writings of Juan Luis Segundo, one of the main representatives of this theology, for being this theologian who, to ours to see, more worked, of explicit form, the question of the ideology and its relation with the faith in the Latin American context

  5. 76 FR 41811 - Kellaway Proposed Low-Effect Habitat Conservation Plan for the Morro Shoulderband Snail, San Luis...

    Science.gov (United States)

    2011-07-15

    ...] Kellaway Proposed Low-Effect Habitat Conservation Plan for the Morro Shoulderband Snail, San Luis Obispo... species in the community of Los Osos, San Luis Obispo County, California. The applicants would implement a... Los Osos, San Luis Obispo County, California. The applicants are requesting a permit for take of Morro...

  6. In memory of Luis Bernardo López

    Directory of Open Access Journals (Sweden)

    Escuela de Estudios en Psicoanálisis y Cultura

    2017-01-01

    Full Text Available In this issue of the magazine From the Garden of Freud we want to remember what the presence of Luis Bernardo López meant in the spirit of this publication. The design and the initial model were the work of Santiago Mutis, as well as the idea of inviting a plastic artist for each number and the care of the graphic part for that exercise. However, Luis Bernardo also participated in his conception, and in his birth, in 2001, since it was his first director and editor, work that continued the following year to later take back the address of the number 7 and to advance the graphic edition of the Numbers 8 to 13. In this work I knew how to give the best shape to the project of a serial publication with which we dreamed since the year 2000.

  7. 75 FR 17430 - Hopper Mountain, Bitter Creek, and Blue Ridge National Wildlife Refuges, Kern, San Luis Obispo...

    Science.gov (United States)

    2010-04-06

    ...] Hopper Mountain, Bitter Creek, and Blue Ridge National Wildlife Refuges, Kern, San Luis Obispo, Tulare... Wildlife Refuges (NWRs) located in Kern, San Luis Obispo, Tulare, and Ventura counties of California. We... developing a CCP for Hopper Mountain, Bitter Creek, and Blue Ridge NWRs in Kern, San Luis Obispo, Tulare, and...

  8. Geologic Map of the San Luis Quadrangle, Costilla County, Colorado

    Science.gov (United States)

    Machette, Michael N.; Thompson, Ren A.; Drenth, Benjamin J.

    2008-01-01

    The map area includes San Luis and the primarily rural surrounding area. San Luis, the county seat of Costilla County, is the oldest surviving settlement in Colorado (1851). West of the town are San Pedro and San Luis mesas (basalt-covered tablelands), which are horsts with the San Luis fault zone to the east and the southern Sangre de Cristo fault zone to the west. The map also includes the Sanchez graben (part of the larger Culebra graben), a deep structural basin that lies between the San Luis fault zone (on the west) and the central Sangre de Cristo fault zone (on the east). The oldest rocks exposed in the map area are the Pliocene to upper Oligocene basin-fill sediments of the Santa Fe Group, and Pliocene Servilleta Basalt, a regional series of 3.7?4.8 Ma old flood basalts. Landslide deposits and colluvium that rest on sediments of the Santa Fe Group cover the steep margins of the mesas. Rare exposures of the sediment are comprised of siltstones, sandstones, and minor fluvial conglomerates. Most of the low ground surrounding the mesas and in the graben is covered by surficial deposits of Quaternary age. The alluvial deposits are subdivided into three Pleistocene-age units and three Holocene-age units. The oldest Pleistocene gravel (unit Qao) forms extensive coalesced alluvial fan and piedmont surfaces, the largest of which is known as the Costilla Plain. This surface extends west from San Pedro Mesa to the Rio Grande. The primary geologic hazards in the map area are from earthquakes, landslides, and localized flooding. There are three major fault zones in the area (as discussed above), and they all show evidence for late Pleistocene to possible Holocene movement. The landslides may have seismogenic origins; that is, they may be stimulated by strong ground shaking during large earthquakes. Machette and Thompson based this geologic map entirely on new mapping, whereas Drenth supplied geophysical data and interpretations.

  9. Optical spectroscopy and luminescence quenching of LuI3:Ce3+

    International Nuclear Information System (INIS)

    Birowosuto, M.D.; Dorenbos, P.; Haas, J.T.M. de; Eijk, C.W.E. van; Kraemer, K.W.; Guedel, H.U.

    2006-01-01

    Optical spectroscopy of LuI 3 doped with Ce 3+ using ultraviolet and visible light excitation is reported. LuI 3 host excitation and emission and 4f-5d excitation and emission of Ce 3+ are observed. An empirical model based on crystal field splitting was used to estimate the energy of the highest 4f-5d excitation band. The crystal field splitting and centroid shift were compared to those of LuCl 3 :Ce 3+ and LuBr 3 :Ce 3+ . Temperature dependence of X-ray excited luminescence spectra shows thermal quenching, whereas that of the decay curve of Ce 3+ emission excited at the lowest 5d band of Ce 3+ does not indicate the presence of quenching of Ce 3+ emission for temperature below 625K. The quenching in LuI 3 :Ce 3+ therefore occurs before the 5d Ce 3+ emission takes place

  10. The cinephilic citation in the essay films by José Luis Guerin and Isaki Lacuesta

    OpenAIRE

    Vidal, Belén

    2014-01-01

    This paper investigates the contemporary turn to cinephilia as an object of theoretical analysis and historiographical investigation through the essay films by José Luis Guerin and Isaki Lacuesta. In particular, I focus on Innisfree (José Luis Guerin 1990), Tren de sombras (Train of Shadows, José Luis Guerin 1997), Las variaciones Marker (The Marker Variations, Isaki Lacuesta 2008) and La noche que no acaba (All the Night Long, Isaki Lacuesta 2010). This work recovers and restages “cinephilic...

  11. Solution to the colloidal silica problem in the San Luis Potosi power plant; Solucion del problema de silice coloidal en la central termoelectrica San Luis Potosi

    Energy Technology Data Exchange (ETDEWEB)

    Lopez Rubalcava, Humberto [Comision Federal de Electricidad (CFE), Mexico, D. F. (Mexico); Mercado, Sergio [Instituto de Investigaciones Electricas, Cuernavaca (Mexico); Guerra, Protasio [Comision Federal de Electricidad (CFE), Mexico, D. F. (Mexico)

    1988-12-31

    In June 1986 the Comision Federal de Electricidad (CFE) made tests to raise the load of the first normalized unit of 350 MW of the San Luis Potosi Power Plant; although the new system for colloidal silica removal had not yet been installed, consisting of a hollow fibers ultra-filtration system with a capacity of 110 m{sup 3}, that for the first time would be applied in a Mexican power plant. It was decided to install this system due to the fact that the well water supplying this power plant comes from a geothermal reservoir, with water at 38 degrees Celsius and a silica content of 15 to 250 parts per billion (ppb) of colloidal silica, which makes it necessary to eliminate it in order to enable the boiler operation at its design conditions (175 bars (2573 psig) and 540 degrees Celsius). Although a demineralizing plant existed for the boiler feed water make up, the ion exchange resins were not able to retain the colloidal silica. Also, the First Unit operation was held at 25% of its rated capacity; in trying to raise the output to 50%, the silica concentration in the boiler water went over the allowed limits, resulting in a concentration of 1,500 ppb in the boiler water and 28 ppb in the steam. One the ultra-filtration plant was installed, the power plant operated at full rated capacity with silica concentrations in the steam lower than the permitted concentration, i.e. 10 ppb . By the end of 1987 the Second Unit of 350 MW was put into operation with the ultra-filtration system in operation, reaching full load without any problem. Once confirmed the efficiency of the ultra-filtration for the colloidal silica removal, CFE will apply this system in other power plants of the country having the same problem. [Espanol] En junio de 1986, la Comision Federal de Electricidad (CFE) efectuo pruebas de elevacion de carga en la primera unidad normalizada de 350 MW de la central termoelectrica San Luis Potosi; sin embargo, aun no se terminaba de instalar el nuevo sistema para la

  12. 78 FR 73557 - Guadalupe-Nipomo Dunes National Wildlife Refuge, San Luis Obispo County, CA: Intent To Prepare a...

    Science.gov (United States)

    2013-12-06

    ...-FF08R00000] Guadalupe-Nipomo Dunes National Wildlife Refuge, San Luis Obispo County, CA: Intent To Prepare a...) for the Guadalupe-Nipomo Dunes National Wildlife Refuge located in San Luis Obispo County of... (Refuge) in San Luis Obispo County, California. This notice complies with our CCP policy to (1) advise...

  13. Art as Critical Public Pedagogy: A Qualitative Study of Luis Camnitzer and His Conceptual Art

    Science.gov (United States)

    Zorrilla, Ana; Tisdell, Elizabeth J.

    2016-01-01

    This qualitative study explored the connection between art and adult education for critical consciousness from the perspective and work of conceptual artist, Luis Camnitzer. The theoretical framework is grounded in the critical public pedagogy literature. Data collection methods included interviews with conceptual artist Luis Camnitzer and with…

  14. The Prehistory of Discovery: Precursors of Representational Change in Solving Gear System Problems.

    Science.gov (United States)

    Dixon, James A.; Bangert, Ashley S.

    2002-01-01

    This study investigated whether the process of representational change undergoes developmental change or different processes occupy different niches in the course of knowledge acquisition. Subjects--college, third-, and sixth-grade students--solved gear system problems over two sessions. Findings indicated that for all grades, discovery of the…

  15. Keisri madrusest impeeriumi esivedurijuhiks / Lui Pikkov ; kommenteerinud Hans Treimann

    Index Scriptorium Estoniae

    Pikkov, Lui, 1935-2008

    2009-01-01

    Lui Pikkov oma onust Otto Piksarist (Pikkov), kes sündis Raplamaal Saunakülas, oli madruseks Nikolai II jahtlaeval Poljarnaja Zvezda, töötas vedurijuhina Eestis, oli Eesti NSV Ülemnõukogu saadik

  16. Geothermal resource assessment of western San Luis Valley, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    Zacharakis, Ted G.; Pearl, Richard Howard; Ringrose, Charles D.

    1983-01-01

    The Colorado Geological Survey initiated and carried out a fully integrated assessment program of the geothermal resource potential of the western San Luis Valley during 1979 and 1980. The San Luis Valley is a large intermontane basin located in southcentral Colorado. While thermal springs and wells are found throughout the Valley, the only thermal waters found along the western part of the Valley are found at Shaw Warm Springs which is a relatively unused spring located approximately 6 miles (9.66 km) north of Del Norte, Colorado. The waters at Shaws Warm Spring have a temperature of 86 F (30 C), a discharge of 40 gallons per minute and contain approximately 408 mg/l of total dissolved solids. The assessment program carried out din the western San Luis Valley consisted of: soil mercury geochemical surveys; geothermal gradient drilling; and dipole-dipole electrical resistivity traverses, Schlumberger soundings, Audio-magnetotelluric surveys, telluric surveys, and time-domain electro-magnetic soundings and seismic surveys. Shaw Warm Springs appears to be the only source of thermal waters along the western side of the Valley. From the various investigations conducted the springs appear to be fault controlled and is very limited in extent. Based on best evidence presently available estimates are presented on the size and extent of Shaw Warm Springs thermal system. It is estimated that this could have an areal extent of 0.63 sq. miles (1.62 sq. km) and contain 0.0148 Q's of heat energy.

  17. 75 FR 76726 - San Luis Solar, LLC; Supplemental Notice That Initial Market-Based Rate Filing Includes Request...

    Science.gov (United States)

    2010-12-09

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Docket No. ER11-2196-000] San Luis Solar, LLC; Supplemental Notice That Initial Market- Based Rate Filing Includes Request for Blanket... proceeding of San Luis [[Page 76727

  18. En el día del bibliotecario: Homenaje al Doctor Luis Ángel Arango

    Directory of Open Access Journals (Sweden)

    Ernesto Delgado

    1962-04-01

    Full Text Available Palabras pronunciadas por el presidente de la Asociación Colombiana de Bibliotecarios, señor Ernesto Delgado, en el Salón de Actos de la Biblioteca Luis Ángel Arango, el sábado 28 de abril, Día del Bibliotecario, con motivo del homenaje que dicha corporación rindió a la memoria del doctor Luis Ángel Arango.

  19. El confesor regio Fray Luis Aliaga y la controversia Inmaculista

    Directory of Open Access Journals (Sweden)

    Callado Estela, Emilio

    2016-06-01

    Full Text Available The present article analyses the participation of the aragonese dominican monk Luis Aliaga (Zaragoza, 1565-† Zaragoza, 1626, last confessor of Philip III and Inquiring general of the Hispanic Monarchy from 1619, in one of the most white hot theological controversies along the 17th century: the Immaculate Conception of the Virgin MaryEl presente artículo analiza la participación del dominico aragonés fray Luis Aliaga (Zaragoza, 1565-† Zaragoza, 1626 , último confesor de Felipe III e Inquisidor general de la Monarquía Hispánica desde 1619, en una de las controversias teológicas más candentes a lo largo del siglo XVII: la Inmaculada Concepción de la Virgen María.

  20. Vida y obra de Luis Jiménez Moreno (1929-2007

    Directory of Open Access Journals (Sweden)

    Antonio Jiménez García

    2008-10-01

    Full Text Available Luis Jiménez Moreno passed away on 27 of October, 2007, 77 years old. For the last 30 years he was professor at Universidad Complutense de Madrid. He became Full Professor. He had studied in Salamanca, Roma, Valencia and München. He got a Ph. Degree whith a tesis about Nietzsche`s Antropological Thought by leading of José Luis López Aranguren. He was High School Teacher in Andujar, Ávila and Badalona; after he was professor at Universities of Barcelona and Madrid. This article develops information about his life and his works: books, articles, essays, conferences, papers to Congress, Symposios, Scientic meetings…

  1. Origen, protagonistas y alianzas. El Banco de San Luis Potosí, 1897-1916

    Directory of Open Access Journals (Sweden)

    Moisés Gámez Rodriguez

    2017-04-01

    Full Text Available En este trabajo se expone el origen de la banca en San Luis Potosí, cuyo estudio se centra a partir de la legislación bancaria de 1897, que representa históricamente la institucionalización y modernización de la empresa bancaria mexicana. Como punto de partida se plantea que los perfiles financieros y empresariales de los involucrados en el nacimiento del Banco de San Luis Potosí, y representados en los miembros de su Consejo de Administración, son importantes para entender la configuración del sistema, y también que las redes extendidas en torno a dicha empresa muestran prácticas financieras de la economía de México en el último cuarto del siglo XIX. _________________________ This article explains the origin of banking in San Luis Potosi from the legislation in 1897, which historically represents the institutionalization and modernization of Mexican banking companies. As a starting point, it argues that financial and business profiles of those involved in the birth of Bank of San Luis Potosi and represented in the Board of Directors are important to understand the system configuration. Furthermore, the networks extended around the banking company show financial practices of Mexican economy in the last quarter of the 19th century.

  2. Serendipity in the Stacks: Libraries, Information Architecture, and the Problems of Accidental Discovery

    Science.gov (United States)

    Carr, Patrick L.

    2015-01-01

    Serendipity in the library stacks is generally regarded as a positive occurrence. While acknowledging its benefits, this essay draws on research in library science, information systems, and other fields to argue that, in two important respects, this form of discovery can be usefully framed as a problem. To make this argument, the essay examines…

  3. Amphibians and reptiles of the state of San Luis Potosí, Mexico, with comparisons with adjoining states.

    Science.gov (United States)

    Lemos-Espinal, Julio A; Smith, Geoffrey R; Woolrich-Piña, Guillermo A

    2018-01-01

    A summary of the species of amphibians and reptiles of the state has been compiled, including their geographic distributions, habitats, and conservation statuses. The herpetofauna of San Luis Potosí consists of 41 species of amphibians and 141 species of reptiles. San Luis Potosí shares the highest number of species with Hidalgo and Tamaulipas, and the least number of species with Nuevo León. In San Luis Potosí, there are several taxa of particular conservation concern including salamanders, emydid and trionychid turtles, anguid and xenosaurid lizards, and natricid and colubrid snakes.

  4. Port San Luis, California Tsunami Forecast Grids for MOST Model

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Port San Luis, California Forecast Model Grids provides bathymetric data strictly for tsunami inundation modeling with the Method of Splitting Tsunami (MOST)...

  5. 78 FR 16569 - Iowa Pacific Holdings, LLC, Permian Basin Railways, and San Luis & Rio Grande Railroad-Corporate...

    Science.gov (United States)

    2013-03-15

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35721] Iowa Pacific Holdings, LLC, Permian Basin Railways, and San Luis & Rio Grande Railroad--Corporate Family Transaction... subsidiaries Permian Basin Railways (PBR) and San Luis & Rio Grande Railroad (SLRG), and Massachusetts Coastal...

  6. Magmatism and mineralization ages from northeast area of La Sierra de San Luis, Argentina

    International Nuclear Information System (INIS)

    Ulacco, Jose H

    2001-01-01

    Three igneous rock groups, characterized as pre, sin and post-kinematics, have intruded the crystalline basement of Sierra de San Luis, Argentina. The ore deposits are associated with Devonian to Carboniferous epizonal granite stocks and batholiths in an area underlain by metamorphic rocks. This granitoids are characterized as post-kinematics magmatism. Model lead ages on the ore deposits (338,8 - 292,1 Ma) are strongly supported by K-Ar ages of the intrusives. The bulk of the north Sierra de San Luis ore deposits are genetically related to late Carboniferous granite plutons. The ore bodies are tungsten veins with greisen envelopes, lead veins, epithermal fluorite veins and REE and Th deposit. A generalized scheme of ore bodies related to granites is proposed. The ore deposits and their lithotectonic setting are characteristic of Gondwana metallogenetic Epoch in the Sierra de San Luis (au)

  7. Amphibians and reptiles of the state of San Luis Potosí, Mexico, with comparisons with adjoining states

    Science.gov (United States)

    Lemos-Espinal, Julio A.; Smith, Geoffrey R.; Woolrich-Piña, Guillermo A.

    2018-01-01

    Abstract A summary of the species of amphibians and reptiles of the state has been compiled, including their geographic distributions, habitats, and conservation statuses. The herpetofauna of San Luis Potosí consists of 41 species of amphibians and 141 species of reptiles. San Luis Potosí shares the highest number of species with Hidalgo and Tamaulipas, and the least number of species with Nuevo León. In San Luis Potosí, there are several taxa of particular conservation concern including salamanders, emydid and trionychid turtles, anguid and xenosaurid lizards, and natricid and colubrid snakes. PMID:29731682

  8. Exposiciones 1958, presentadas en la Biblioteca Luis Ángel Arango

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    1958-12-01

    Full Text Available Se describe el desarrollo de la actividades culturales del año 1958 correspondientes a las exposiciones de arte presentadas en la Biblioteca Luis Ángel Arango del Banco de la República.

  9. 76 FR 31678 - San Luis & Rio Grande Railroad-Continuance in Control Exemption-Saratoga and North Creek Railway...

    Science.gov (United States)

    2011-06-01

    ... DEPARTMENT OF TRANSPORTATION Surface Transportation Board [Docket No. FD 35499] San Luis & Rio Grande Railroad--Continuance in Control Exemption--Saratoga and North Creek Railway, LLC San Luis & Rio Grande Railroad (SLRG), a Class III rail carrier, has filed a verified notice of exemption to continue in...

  10. Geomorphic evolution of the San Luis Basin and Rio Grande in southern Colorado and northern New Mexico

    Science.gov (United States)

    Ruleman, Chester A.; Machette, Michael; Thompson, Ren A.; Miggins, Dan M; Goehring, Brent M; Paces, James B.

    2016-01-01

    The San Luis Basin encompasses the largest structural and hydrologic basin of the Rio Grande rift. On this field trip, we will examine the timing of transition of the San Luis Basin from hydrologically closed, aggrading subbasins to a continuous fluvial system that eroded the basin, formed the Rio Grande gorge, and ultimately, integrated the Rio Grande from Colorado to the Gulf of Mexico. Waning Pleistocene neotectonic activity and onset of major glacial episodes, in particular Marine Isotope Stages 11–2 (~420–14 ka), induced basin fill, spillover, and erosion of the southern San Luis Basin. The combined use of new geologic mapping, fluvial geomorphology, reinterpreted surficial geology of the Taos Plateau, pedogenic relative dating studies, 3He surface exposure dating of basalts, and U-series dating of pedogenic carbonate supports a sequence of events wherein pluvial Lake Alamosa in the northern San Luis Basin overflowed, and began to drain to the south across the closed Sunshine Valley–Costilla Plain region ≤400 ka. By ~200 ka, erosion had cut through topographic highs at Ute Mountain and the Red River fault zone, and began deep-canyon incision across the southern San Luis Basin. Previous studies indicate that prior to 200 ka, the present Rio Grande terminated into a large bolson complex in the vicinity of El Paso, Texas, and systematic, headward erosional processes had subtly integrated discontinuously connected basins along the eastern flank of the Rio Grande rift and southern Rocky Mountains. We propose that the integration of the entire San Luis Basin into the Rio Grande drainage system (~400–200 ka) was the critical event in the formation of the modern Rio Grande, integrating hinterland basins of the Rio Grande rift from El Paso, Texas, north to the San Luis Basin with the Gulf of Mexico. This event dramatically affected basins southeast of El Paso, Texas, across the Chisos Mountains and southeastern Basin and Range province, including the Rio

  11. Embarazo en la adolescencia: su comportamiento en San Luis Pregnancy in adolescence: its behavior in San Luis municipality

    Directory of Open Access Journals (Sweden)

    Dania Rangel Díaz

    2012-08-01

    Full Text Available Introducción: El embarazo en las edades tempranas, sin la adecuada preparación biológica y psicológica, trae al contraste una serie de dificultades y problemas. Objetivo: Evaluar el comportamiento del embarazo en la adolescencia en el municipio de "San Luis" durante el período 2005-2010. Material y método: Se realizó una investigación aplicada partiendo de los conocimientos teóricos y prácticos. A partir de la metodología cuantitativa se presenta un diseño longitudinal, retrospectivo, analítico y descriptivo. Se utilizó como universo (2165 todas las mujeres embarazadas desde enero de 2005 a diciembre del año 2010; la muestra la constituyeron todas las embarazadas adolescentes (405 pertenecientes al municipio San Luis. Las técnicas y procedimientos de obtención de la información fue a través de la revisión documental. Se hizo una minuciosa revisión de las historias clínicas y de la información que se guarda en archivo del departamento de genética municipal y se recolectaron datos como: la edad materna, causa del embarazo, ocupación, las enfermedades presentadas durante el embarazo, el peso al nacer y el abandono escolar. Se utilizó el método empírico empleando la media porcentual como medida de tendencia central para variables cualitativas. Resultados: Predominan las adolescentes entre 16 y 18 años de edad, todas estudiantes; la principal causa del embarazo fue el desconocimiento. Se realizó una captación precoz al mayor porciento de ellas; como la enfermedad asociada predominó la hipertensión arterial. Conclusiones: Se logró un peso adecuado al final de la gestación y en su mayoría las estudiantes no continuaron los estudios.Introduction: pregnancy in early ages, without sufficient biological and psychological preparation, brings about a series of difficulties and problems. Objective: to assess the behavior of pregnancy in adolescence in “San Luis” municipality during a five-year period (2005

  12. JORGE LUIS BORGES – SERGIO PITOL: INFLUENCES, SYMMETRIES AND LITERARY TRANSFERENCES JORGE LUIS BORGES – SERGIO PITOL: INFLUENCIAS, SIMETRÍAS Y TRANSFERENCIAS LITERARIAS

    Directory of Open Access Journals (Sweden)

    Alejandro Hermosilla Sánchez

    2011-02-01

    Full Text Available In the entire Pitol‘s work, there is a continuous masquerade and an ungovernable fusion of the forces that link his life and his literature that has dislocated absolutely the "certainties" that we can get to own. Above all, for having been capable to improve the autobiographic genre helped by his way to understand, as Jorge Luis Borges and Marcel Schowb did, the reality as unverified and fiction as one more of many possibilities of what is "real". In this article, we will try to go deeper into the "discredit of the autobiographic and critical genre made by Sergio Pitol in La trilogía de la memoria thanks to the influence of Jorge Luis Borge´s literature.En toda la obra de Pitol hay un enmascaramiento continuo y una fusión ingobernable de las fuerzas que vinculan su vida y su literatura que ha terminado por dislocar absolutamente las "certezas" que podemos a llegar a poseer sobre ambas. Ante todo, por haber sido capaz de dar una nueva vuelta de tuerca más al género autobiográfico gracias a su manera de entender, tal y como hicieron Jorge Luis Borges y el francés Marcel Schwob, la realidad como inverificable y la ficción como una más de las muchas posibilidades de lo "real". En este artìculo, intentaremos profundizar en la desacreditación del género autobiográfico y crítico hecho por Pitol en La trilogía de la memoria o Domar a la divina garza gracias a la influencia de la literatura de Borges.

  13. Topology Discovery Using Cisco Discovery Protocol

    OpenAIRE

    Rodriguez, Sergio R.

    2009-01-01

    In this paper we address the problem of discovering network topology in proprietary networks. Namely, we investigate topology discovery in Cisco-based networks. Cisco devices run Cisco Discovery Protocol (CDP) which holds information about these devices. We first compare properties of topologies that can be obtained from networks deploying CDP versus Spanning Tree Protocol (STP) and Management Information Base (MIB) Forwarding Database (FDB). Then we describe a method of discovering topology ...

  14. The San Luis Project: An Attempt to Decentralize Physics in Mexico

    Science.gov (United States)

    Will, T. A.; Valladares, A. A.

    1976-01-01

    Described is a project being conducted by the Physics Institute of the University of San Luis Potori, Mexico, in order to avoid concentrating physics education and research activities in Mexico City. (SL)

  15. 76 FR 33362 - Request for Interest in Lease Arrangement on Federal Lands, San Luis Project, Los Banos, California

    Science.gov (United States)

    2011-06-08

    ... facilitating environmentally appropriate renewable-energy projects involving solar, wind and waves, geothermal... Federal Lands, San Luis Project, Los Banos, California AGENCY: Bureau of Reclamation, Interior. ACTION... energy project(s) in a lease arrangement on existing Reclamation lands in the vicinity of the San Luis...

  16. 77 FR 21797 - Hopper Mountain, Bitter Creek, and Blue Ridge National Wildlife Refuges, Ventura, Kern, San Luis...

    Science.gov (United States)

    2012-04-11

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R8-R-2011-N253: FXRS12650800000S3-112-FF08R00000] Hopper Mountain, Bitter Creek, and Blue Ridge National Wildlife Refuges, Ventura, Kern, San Luis... acres, primarily in Kern County and extending into San Luis Obispo and Ventura Counties. Blue Ridge NWR...

  17. Commercial production of ethanol in the San Luis Valley, Colorado. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hewlett, E.M.; Erickson, M.V.; Ferguson, C.D.; Boswell, B.S.; Walter, K.M.; Hart, M.L.; Sherwood, P.B.

    1983-07-01

    The commercial feasibility of producing between 76 and 189 million liters (20 to 50 million gallons) of ethanol annually in the San Luis Valley, Colorado using geothermal energy as the primary heat source was assessed. The San Luis Valley is located in south-central Colorado. The valley is a high basin situated approximately 2316 meters (7600 feet) above sea level which contains numerous warm water wells and springs. A known geothermal resource area (IGRA) is located in the east-central area of the valley. The main industry in the valley is agriculture, while the main industry in the surrounding mountains is lumber. Both of these industries can provide feedstocks for the production of ethanol.

  18. José Luis Hidalgo, poeta de los muertos

    Directory of Open Access Journals (Sweden)

    Román GARCÍA-CAMINO MATEOS

    2009-11-01

    Full Text Available RESUMEN: La figura de José Luis Hidalgo (Torres, 1919-Madrid, 1947, poeta y pintor, ha de tomar un nuevo relieve como representante de una generación de autores montañeses que surgió en torno a los años cuarenta. Destaca en su breve obra, al igual que su corta pero intensa vida, la extrema sensibilidad de su poesía en el uso de imágenes, metáforas que acercan sus versos hacia el terreno de lo plástico y sensorial. Las preocupaciones son de profunda raigambre existencialista, al ser nuestro poeta un joven lector de pensadores como Nietzsche, Schopenhauer o Unamuno; es con este último con el que guarda una ineludible afinidad de ideas. La búsqueda que emprende José Luis Hidalgo hacia la verdad se sitúa dentro de una metafísica trascendente y una vertiente religiosa muy significativa, en un diálogo sincero y directo con Dios. Contrasta la sencillez formal de su poesía con el complejo sistema simbólico de elementos naturales, espacios... en los que se mueve dentro del marco fluctuante entre la tradición y la vanguardia; encontramos resonancias que nos llevan desde el romanticismo becqueriano, pasando por el simbolismo, hasta los movimientos vanguardistas —sobre todo el surrealismo— y el grupo poético del 27. La obra de Los muertos supone un momento culmen del dilatado periodo de posguerra.ABSTRACT: The literary figure of José Luis Hidalgo (Torres, 1919-Madrid, 1947, both a poet and a painter, achieves renown once more as a representative of a generation of writers from Cantabria (in the north of Spain which came to light around the 1940's. His work, as brief as his short but intense life, is remarkable for the great feeling of his poetry in the use of imagery and metaphors, which draw his verse near the domain of the vivid and sensorial. His concerns have deep existentialist roots; as a young man the poet was a devoted reader of great thinkers such as Nietzsche, Schopenhauer or Unamuno; it is the latter with whom he has an

  19. Luis Alvarez - a personal approach to physics

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    1988-12-15

    One of the major pioneer figures and outstanding personalities of particle physics, Luis Alvarez, died on 1 September. In addition to his numerous particle physics achievements, he became famous for his ventures in archaeology, palaeontology, and astronomy, and for his inventions. As a tribute to this remarkable man, we publish here some extracts from 'Adventures in Nuclear Physics', given as the 1962 University of California Faculty Research Lecture. According to custom, this presentation is a personalized account rather than an impersonal scientific discourse.

  20. Pionero de la comunicación (Entrevista a Luis Ramiro Beltrán

    Directory of Open Access Journals (Sweden)

    Juan Braun

    2015-01-01

    Full Text Available Luis Ramiro es, sin lugar a dudas, el comunicador más reconocido de la América Latina. Sus ideas circulan libremente en el Norte y en el Sur. Es un líder. Pero pocos saben de su vida. Los esfuerzos que tuvo que hacer para "llegar". De sus primeros años de periodista bohemio, su lucha en la Universidad del Estado de Michigan para sobrevivir a las exigencias de Berlo, Kumata, Rogers y Miller. Y la importancia fundamental en todo esto de su madre, Mama Becha. Nos conocimos allá lejos, en Michigan. Luis Ramiro se graduaba de Doctor, terminaba su "vía crucis". El mío apenas comenzaba. Las ideas de Luis, su diagnóstico de la comunicación en América Latina, tuvieron un profundo impacto en mí que se hizo sentir años después. ¡Gracias! ¡y también alcancé a probar las empanadas de Mama Becha! El Dr. Beltrán habla sobre su vida y el pasado, presente y futuro de la comunicación en América Latina.

  1. 76 FR 45602 - Proposed Safe Harbor Agreement for California Red-Legged Frog, at Swallow Creek Ranch, San Luis...

    Science.gov (United States)

    2011-07-29

    ... DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-R8-ES-2011-N144; 81440-1113-0000-F3] Proposed Safe Harbor Agreement for California Red-Legged Frog, at Swallow Creek Ranch, San Luis Obispo... Ranch in San Luis Obispo County, California. Within the 620 acres of land comprising the Enrolled...

  2. Distribución del ocelote (Leopardus pardalis en San Luis Potosí, México Distribution of the ocelot (Leopardus pardalis in San Luis Potosí, Mexico

    Directory of Open Access Journals (Sweden)

    Jesús Manuel Martínez-Calderas

    2011-09-01

    Full Text Available Para definir la distribución geográfica del ocelote en el estado de San Luis Potosí, México, se obtuvieron nuevos registros de la especie. El estudio se realizó de enero de 2007 a abril de 2009. Se obtuvieron 41 registros de ocelotes por medio de entrevistas y trampeo-fotográfico. Los registros se localizaron en comunidades vegetales de selva baja caducifolia (37%, matorral submontano (22%, bosque de encino (15%, selva mediana (10%, selva alta perennifolia, bosque mesófilo de montaña, bosque de pino-encino y matorral desértico micrófilo (10%. La presencia de ocelotes se ubicó en los municipios de Ciudad del Maíz, El Naranjo, Cerritos, Guadalcázar, San Nicolás Tolentino y Ciudad Valles en de elevaciones de 38 a 2 400 m snm. Los resultados de esta investigación sugieren una distribución del ocelote más hacia el oeste del estado respecto a su distribución original. El presente estudio definió nuevas regiones con presencia de ocelotes que pueden ser consideradas en el desarrollo de estrategias de conservación de la especie en el estado de San Luis Potosí.To determine the geographic distribution of ocelot in the state of San Luis Potosí, Mexico, we obtained new records. The study was conducted from January 2007 to April 2009. We recorded 41 ocelot records by interviews and camera-trapping. Ocelots records were located in tropical deciduous forest (37%, semitropical thornscrub (22%, oak forest (15%, tropical forest (10%, tall tropical deciduous forest, desert scrub, pine-oak forest and clouded forest (10%. Ocelot records were located in the municipalities of Ciudad del Maíz, El Naranjo, Cerritos, Guadalcazar, San Nicolás Tolentino and Ciudad Valles where the elevation ranged from 38 to 2 400 m. The evidence of this research suggests that ocelot range is more extended to the west than its original geographical range. This study defined new regions with presence of ocelots that may be considered to develop conservation strategies

  3. Commercial production of ethanol in the San Luis Valley, Colorado. Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Hewlett, E.M.; Erickson, M.V.; Ferguson, C.D.; Sherwood, P.B.; Boswell, B.S.; Walter, K.M.; Hart, M.L.

    1983-07-01

    The purpose of this study is to assess the commercial feasibility of producing between 76 and 189 million liters (20 and 50 million gallons) of ethanol annually in the San Luis Valley, Colorado using geothermal energy as the primary heat source. The San Luis Valley is located in south-central Colorado. The valley is a high basin situated approximately 2316 meters (7600 feet) above sea level which contains numerous warm water wells and springs. A known geothermal resource area (KGRA) is located in the east-central area of the valley. The main industry in the valley is agriculture, while the main industry in the surrounding mountains is lumber. Both of these industries can provide feedstock for the production of ethanol.

  4. Chasing Personal Meaning: Pedagogical Lessons through Luis Rodriguez's "Always Running"

    Science.gov (United States)

    Theisen-Homer, Victoria

    2014-01-01

    In this autobiographical narrative, the author recounts her experiences teaching the novel "Always Running" by Luis Rodriguez with her English classes at a high school in a gang-heavy area. When she first started teaching, this teacher struggled to engage students. One particularly disruptive student requested to read "Always…

  5. Luis Alvarez - a personal approach to physics

    International Nuclear Information System (INIS)

    Anon.

    1988-01-01

    One of the major pioneer figures and outstanding personalities of particle physics, Luis Alvarez, died on 1 September. In addition to his numerous particle physics achievements, he became famous for his ventures in archaeology, palaeontology, and astronomy, and for his inventions. As a tribute to this remarkable man, we publish here some extracts from 'Adventures in Nuclear Physics', given as the 1962 University of California Faculty Research Lecture. According to custom, this presentation is a personalized account rather than an impersonal scientific discourse

  6. Luis Patiño Camargo Maestro, Investigador, Humanista

    Directory of Open Access Journals (Sweden)

    José Felix Patiño Restrepo

    1992-09-01

    Full Text Available

    Palabras del doctor José Félix Patiño Restrepo, Académico de Número, con motivo de la Sesión Solemne de la Academia Nacional de Medicina para conmemorar el centenario del natalicio del Profesor Luis Patiño Camargo.

    Santafé de Bogotá, noviembre 21 de 1991

    Son varias las semblanzas que distinguidas personalidades de Colombia y del exterior han escrito sobre el Profesor Luis Patiño Camargo, cuya vida ejemplar dejó honda huella en la medicina y la ciencia colombianas: Carlos Lleras Restrepo y Juan Lozano y Lozano en 1978; Augusto Gast Galvis, Fernando Serpa Flórez y Alfonso Jaram illo Salazar en 1979; Eduardo Guzmán Esponda, Remando Groot y José Francisco Socarrás en 1981; Amador Neghme, de Chile en 1987; Ernesto Andradc Valderrama en 1988, y ahora Carlos Sanmartín Barberi.

    “Bella vida y bella muerte la de Luis Patiño Camargo, pensaba yo cuando iba caminando detrás del féretro, después de los sencillos oficios en la iglesia de Iza, hacia el cementerio campesino donde él dispuso que se enterrara en medio de las tumbas de sus padres y debajo de los pinos que plantó con su propia mano”. Así inició Carlos Lleras Restrepo un sentido artículo sobre Patiño Camargo publicado en la Nueva Frontera a los pocos días de su muerte, acaecida en Sogamoso el 13 de noviembre de 1978. Porque ese fue su deseo: reposar para siempre en el cementerio que domina su bello pueblo andino, Iza, donde había nacido el 24 de noviembre de 1891.

    Dijo Gast Galvis: “El Dr. Patiño, como el cacique de Inza, después de mucho peregrinar por todo el territorio colombiano, encontró un lugar de brisas tibias, cielo siempre azul, abundantes aguas, suelo fértil, en donde se pudiera vivir y morir en paz”.

    Científico, maestro, médico, naturalista, filósofo, humanista, todo eso fue Luis Patiño Camargo, y ninguno de estos términos lo caracteriza de por sí, sino más bien el conjunto de ellos

  7. Geology and petrography of the Socoscora Sierra . Province of San Luis. Republica Argentina

    International Nuclear Information System (INIS)

    Carugno Duran, A.

    1998-01-01

    The following paper include an study geological and petrographic of the Sierra de Socoscora. San Luis, Argentina. This mountainas is a block with less elevation that the Sierra de San Luis, and it located in the west center of it. It' s formed by an crystalline basement composed by metamorphic haigh grade rocks, with a penetrative foliation of strike N-S. in this context is possible to define petrographicly the following units, migmatitic that fill a big part of the mountain, amphibolites, marbles, skarns, milonites and pegmatites. This units have amphibolitic facies assemblanges mineral and in some them, we can observe retrograde metamorphism of the greesnschist facies. The metamorphic structure is complex and evidence at least three deformation event

  8. Social Integration and Health Behavioral Change in San Luis, Honduras

    Science.gov (United States)

    McQuestion, Michael J.; Calle, Ana Quijano; Drasbek, Christopher; Harkins, Thomas; Sagastume, Lourdes J.

    2010-01-01

    This study explores the effects of social integration on behavioral change in the course of an intensive, community-based public health intervention. The intervention trained volunteers and mobilized local organizations to promote 16 key family health practices in rural San Luis, Honduras, during 2004 to 2006. A mixed methods approach is used.…

  9. Expansão espacial da leishmaniose visceral americana em São Luis, Maranhão, Brasil Space expansion of the American visceral leishmaniasis in São Luis, Maranhão, Brazil

    Directory of Open Access Journals (Sweden)

    Wellington da Silva Mendes

    2002-06-01

    Full Text Available Descreve-se a ocupação espacial no município de São Luis e a expansão da leishmaniose visceral americana(LVA na mesma. Foram analisadas as fichas de registro de atendimento de casos de leishmaniose visceral da Diretoria Regional da Fundação Nacional de Saúde do Maranhão no período de setembro de 1982 a dezembro de 1996, assim como documentos oficiais sobre a ocupação espacial do município. Foi observado que os casos de LVA ao longo da evolução da epidemia em São Luis apresentaram distribuição espacial e concentração semelhantes a apresentada pelo fluxo migratório na cidade no mesmo período.The space occupation and the expansion of American visceral leishmaniasis (AVL were described in the municipality of São Luis, Maranhão, Northeast Brazil. AVL medical notes from the Fundação Nacional de Saúde as well as official documents about the space occupation were analyzed from September 1982 to December 1996. AVL cases were more likely to occur in recently settled suburbs and tended to follow the same spatial pattern observed for land occupations secondary to migratory fluxes.

  10. Doctor Ramón Luis Miranda Torres, su relación con las neurociencias

    OpenAIRE

    Hodelín Tablada,Ricardo

    2005-01-01

    Objetivo: en el presente trabajo se reseña la relación del doctor Ramón Luis Miranda con las neurociencias, dirigido a destacar su inclinación por estas disciplinas. Desarrollo: conocido en la historiografía médica como el médico de José Martí el apóstol cubano el doctor Ramón Luis Miranda Torres, se destacó en otros aspectos poco divulgados, por lo que opinamos que no se le ha otorgado su verdadera dimensión. Nacido en la ciudad de Matanzas, Cuba, estudió medicina en Francia y desde sus años...

  11. Los avisos para la muerte de Luis Ramirez de Arellano

    Directory of Open Access Journals (Sweden)

    Inmaculada Osuna

    2009-01-01

    Full Text Available Avisos para la muerte (1634, compiled by Luis Ramírez de Arellano, gathers, along with other complementary materials (among these, two prayers written in verse for before confession and before communion, and an act of contrition in prose, thirty poems that are presented as models for prayers addressed to a crucified Christ in the moment of his death. These poems emerge from a group initiative in which notable poets from the Madrid court took part, poets such as Lope de Vega, Pedro Calderón de la Barca, José de Pellicer, José de Valdivielso, Luis Vélez de Guevara, Juan Pérez de Montalbán and Francisco de Rojas Zorrilla. My article examines the social context in which this poetic collection is born, the composition of the book, its successful publishing history throughout two centuries as well as the reiterative representation in the poems of particular meditatio mortis topics (the staging of agony; the expression of repentance, love for Christ and hope for his mercy; and the contemplation of Christ’s body on the cross.

  12. Moessbauer, TEM/SAED and XRD investigation on waste dumps of the Valea lui Stan gold mines

    Energy Technology Data Exchange (ETDEWEB)

    Constantinescu, Serban Grigore, E-mail: sconst@infim.ro [National Institute of Materials Physics, Bucharest-Magurele (Romania); Udubasa, Sorin S.; Udubasa, Gheorghe [University of Bucharest, Fac. of Geology and Geophysics (Romania); Kuncser, Victor; Popescu-Pogrion, Nicoleta; Mercioniu, Ionel; Feder, Marcel [National Institute of Materials Physics, Bucharest-Magurele (Romania)

    2012-03-15

    The complementary investigation techniques, Moessbauer spectroscopy, transmission electron microscopy with selected area electron diffraction (TEM/SAED), X-ray diffraction (XRD) have been used to investigate the fate of the Valea lui Stan, Romania, gold-ore nanoscale-minerals during the long time of residence in the waste dumps. The preliminary investigations showed such waste dumps to contain significant amount of metals which cannot be identified by conventional methods. An intense research activity started up in order to evaluate the possibilities to recycle Valea lui Stan waste dumps and to recover metals by chemical or phytoextraction procedures. The waste dumps naturally show different mineral constituents with clay minerals as major phases, observed by XRD-technique. Although the waste dumps materials have whitish-yellowish colours, MOeSSBAUER technique evidences the presence of the finely dispersed iron bearing minerals. The authors are focusing to inspect and analyze Fe-compounds in the samples collected from Valea lui Stan's waste dumps in order to identify the magnetic phases by Moessbauer technique.

  13. Neuroimaging Features of San Luis Valley Syndrome

    Directory of Open Access Journals (Sweden)

    Matthew T. Whitehead

    2015-01-01

    Full Text Available A 14-month-old Hispanic female with a history of double-outlet right ventricle and developmental delay in the setting of recombinant chromosome 8 syndrome was referred for neurologic imaging. Brain MR revealed multiple abnormalities primarily affecting midline structures, including commissural dysgenesis, vermian and brainstem hypoplasia/dysplasia, an interhypothalamic adhesion, and an epidermoid between the frontal lobes that enlarged over time. Spine MR demonstrated hypoplastic C1 and C2 posterior elements, scoliosis, and a borderline low conus medullaris position. Presented herein is the first illustration of neuroimaging findings from a patient with San Luis Valley syndrome.

  14. Future Drinking Water Supply, Spatial Analysis and Vulnerability of the City of San Luis Potosi, Mexico

    Directory of Open Access Journals (Sweden)

    Carlos Contreras Servín

    2008-01-01

    Full Text Available This paper discusses and presents the physical, social and economic circumstances that affect the overall picture and the current issues that involve the drinking water supply for the metropolitan area of San Luis Potosi. The relationship between water availability and increasing population, as well as the evolution of the groundwater extraction, are among the topics addressed here. Additionally, this research shows a diagnosis of the current situation of the drinking water supply in San Luis Potosi and the surrounding areas, as well as the likely scenario in the near future.

  15. Airborne electromagnetic and magnetic survey data of the Paradox and San Luis Valleys, Colorado

    Science.gov (United States)

    Ball, Lyndsay B.; Bloss, Benjamin R.; Bedrosian, Paul A.; Grauch, V.J.S.; Smith, Bruce D.

    2015-01-01

    In October 2011, the U.S. Geological Survey (USGS) contracted airborne magnetic and electromagnetic surveys of the Paradox and San Luis Valleys in southern Colorado, United States. These airborne geophysical surveys provide high-resolution and spatially comprehensive datasets characterizing the resistivity structure of the shallow subsurface of each survey region, accompanied by magnetic-field information over matching areas. These data were collected to provide insight into the distribution of groundwater brine in the Paradox Valley, the extent of clay aquitards in the San Luis Valley, and to improve our understanding of the geologic framework for both regions. This report describes these contracted surveys and releases digital data supplied under contract to the USGS.

  16. Luis Buñuel: trascendiendo el tópico

    Directory of Open Access Journals (Sweden)

    Dr. Manuel Carlos Fernández Sánchez

    2001-01-01

    Full Text Available En 1900 nace el cineasta Luis Buñuel en Calanda, Aragón. En el año 2000 se celebró en distintos ámbitos cinematográficos y televisivos de todo el mundo el centenario de su nacimiento. Festivales de cine, cadenas de televisión por satélite u onda hertziana, periódicos y revistas se hacen eco de la enorme trascendencia del lenguaje cinematográfico buñueliano. Este estudio sobre la última de sus películas rodada en Andalucía, concretamente en Sevilla, pretende aportar un nuevo análisis sobre esta obra que trascendió el tópico andaluz.ABSTRACIn 1900 the film director Luis Buñuel is born in Calanda, Aragón. In 2000, it took place the centennial of his birth in different film and television environments in all over the world. The transcendency of film languaje used by Buñuel has been anlysed in cinema festivals, television, newspapers and magazines. This study, focus on his last movies filmed in Andalusia, concretely in Seville, it seeks to contribute with a new analysis on this work that transcended the Andalusian topic.

  17. Theoretical investigations on the high light yield of the LuI3:Ce scintillator

    International Nuclear Information System (INIS)

    Vasil'ev, A.N.; Iskandarova, I.M.; Scherbinin, A.V.; Markov, I.A.; Bagatur'yants, A.A.; Potapkin, B.V.; Srivastava, A.M.; Vartuli, J.S.; Duclos, S.J.

    2009-01-01

    The extremely high scintillation efficiency of lutetium iodide doped by cerium is explained as a result of at least three factors controlling the energy transfer from the host matrix to activator. We propose and theoretically validate the possibility of a new channel of energy transfer to excitons and directly to cerium, namely the Auger process when Lu 4f hole relaxes to the valence band hole with simultaneous creation of additional exciton or excitation of cerium. This process should be efficient in LuI 3 , and inefficient in LuCl 3 . To justify this channel, we perform calculations of density of states using a periodic plane-wave density functional approach. The second factor is the increase of the efficiency of valence hole capture by cerium in the row LuCl 3 -LuBr 3 -LuI 3 . The third one is the increase of the efficiency of energy transfer from self-trapped excitons to cerium ions in the same row. The latter two factors are verified by cluster ab initio calculations. We estimate either the relaxation of these excitations and barriers for the diffusion of self-trapped holes (STH) and self-trapped exciton (STE). The performed estimations theoretically justify the high LuI 3 :Ce 3+ scintillator yield.

  18. Exposiciones: Capuleto en la sala "Luis Ángel Arango"

    Directory of Open Access Journals (Sweden)

    Arístides Meneghetti

    1958-07-01

    Full Text Available La exposición del joven pintor español Francisco Capuleto, realizada en la Biblioteca "Luis Ángel Arango" el pasado mes de mayo, refresca un viejo problema en la conciencia de todo americano. Existen dos Españas diferentes, la una folclórica, de aire flamenco, majas y alegres panderetas, creada para la exportación y el turismo, a que son tan afectas las personas.

  19. Eric Bach : ilustrador de Luis de Góngora

    Directory of Open Access Journals (Sweden)

    María Dolores Antigüedad del Castillo Olivares

    1991-01-01

    Full Text Available El pintor holandés Eric Bach [Eríurt (Alemania 1911] ha mostrado durante el año 1991 sus obras como ilustrador en sendas exposiciones celebradas en Córdoba y Madrid. El artista que reside indistintamente en Munich y Barcelona, expuso las ilustraciones que ha realizado para la edición en alemán de Los veinticuatro sonetos amorosos, heroicos y fúnebres de don Luis de Góngora, edición hecha por encargo del Sr. Rüdiger Kampmann de Munich.

  20. Water Supply: Management of Water Sources in the City of San Luis Potosí (México, 1831-1887

    Directory of Open Access Journals (Sweden)

    Yuritzi Hernández Fuentes

    2015-07-01

    Full Text Available This paper proposes an approach about the management of water sources, hydraulic systems and the measures taken by the city government of San Luis Potosí (México concerning the need of water supply during the years 1831 to 1886. This paper examines two important projects on water management in the city: the aqueduct of La Cañada del Lobo and the policies taken by the authorities on waterways through La Corriente. Both projects faced several problems, including the outbreak of illnesses associated with bodies of water and shortage of liquid flow through the aqueduct of La Cañada del Lobo.

  1. Late Miocene-Pleistocene evolution of a Rio Grande rift subbasin, Sunshine Valley-Costilla Plain, San Luis Basin, New Mexico and Colorado

    Science.gov (United States)

    Ruleman, C.A.; Thompson, R.A.; Shroba, R.R.; Anderson, M.; Drenth, B.J.; Rotzien, J.; Lyon, J.

    2013-01-01

    The Sunshine Valley-Costilla Plain, a structural subbasin of the greater San Luis Basin of the northern Rio Grande rift, is bounded to the north and south by the San Luis Hills and the Red River fault zone, respectively. Surficial mapping, neotectonic investigations, geochronology, and geophysics demonstrate that the structural, volcanic, and geomorphic evolution of the basin involves the intermingling of climatic cycles and spatially and temporally varying tectonic activity of the Rio Grande rift system. Tectonic activity has transferred between range-bounding and intrabasin faults creating relict landforms of higher tectonic-activity rates along the mountain-piedmont junction. Pliocene–Pleistocene average long-term slip rates along the southern Sangre de Cristo fault zone range between 0.1 and 0.2 mm/year with late Pleistocene slip rates approximately half (0.06 mm/year) of the longer Quaternary slip rate. During the late Pleistocene, climatic influences have been dominant over tectonic influences on mountain-front geomorphic processes. Geomorphic evidence suggests that this once-closed subbasin was integrated into the Rio Grande prior to the integration of the once-closed northern San Luis Basin, north of the San Luis Hills, Colorado; however, deep canyon incision, north of the Red River and south of the San Luis Hills, initiated relatively coeval to the integration of the northern San Luis Basin.Long-term projections of slip rates applied to a 1.6 km basin depth defined from geophysical modeling suggests that rifting initiated within this subbasin between 20 and 10 Ma. Geologic mapping and geophysical interpretations reveal a complex network of northwest-, northeast-, and north-south–trending faults. Northwest- and northeast-trending faults show dual polarity and are crosscut by north-south– trending faults. This structural model possibly provides an analog for how some intracontinental rift structures evolve through time.

  2. Western Regional Conference on Testing Problems (7th, Los Angeles, California, March 14, 1958). Testing for the Discovery and Development of Human Talent.

    Science.gov (United States)

    Educational Testing Service, Los Angeles, CA.

    At the seventh Western Regional Conference on Testing Problems, the following speeches were given: (1) "A Guidance Person's Approach to Testing for the Discovery and Development of Human Talent" by Frances D. McGill; (2) "The Instructional Uses of Measurement in the Discovery and Development of Human Talent" by Roy P. Wahle; (3) "New Frontiers of…

  3. Luis José de Tejada y Guzmán : espejo de peregrinos penitentes

    Directory of Open Access Journals (Sweden)

    Darío Achury Valenzuela

    1979-03-01

    Full Text Available Graciela Maturo, docta escritora argentina, ha escrito un estudio documentado y erudito bajo el rubro de Luis de Tejada y su peregrino místico, editado por el Instituto de Literatura Argentina "Ricardo Rojas", de la Universidad de Buenos Aires.

  4. Escrituras, hurtos y reelaboraciones de Luis Hurtado de Toledo (1523-1590): edición de su obra literaria y estudio de su obra impresa

    OpenAIRE

    Gamba Corradine, Jimena

    2014-01-01

    [ES] La tesis doctoral «Escrituras, hurtos y reelaboraciones de Luis Hurtado de Toledo (1523-1590): edición de su obra literaria y estudio de su obra impresa» consiste en la edición de una parte del corpus literario adjudicado a Luis Hurtado de Toledo. Se editan aquí, con notas al texto, los romances en pliego resguardados en RM 259 + [260] (Romance de las notables cosas que tiene la imperial ciudad de Toledo), RM 261 + [261] y 263 (Romance nuevamente hecho por Luis Hurtado, en el qual se co...

  5. “Y SAN LUIS OBEDIENTE RESPONDÍA” LOS TERRATENIENTES DE LA CIUDAD DE SAN LUIS Y EL PLAN SANMARTINIANO (1814 - 1829

    Directory of Open Access Journals (Sweden)

    Melody Celeste Vera

    2015-12-01

    Full Text Available La base fundamental de la identidad de los habitantes de la provincia de San Luis (Argentina y de su historiografía, es el axioma que el pueblo puntano se inmoló por el proyecto sanmartiniano. El Gobernador Intendente Vicente Dupuy (1814-1820 fue el principal colaborador de José de San Martin en la provincia, y el coordinador de las donaciones de bienes y vidas para la causa. Contaba con el apoyo del “cabildo sanmartiniano”, un grupo de vecinos que secundaban sus ideales, apoyaban sus iniciativas y colaboraban materialmente. Pero luego de la caída del gobierno central en 1820 no se ofrece una interpretación sobre el cambio de proyecto político que representó el nuevo Gobernador, José Santos Ortiz (1820-1829. Si se consideran conjuntamente las oposiciones de un grupo de vecinos levantadas durante el gobierno de Dupuy y el accionar de Santos Ortiz durante su mandato, cabe preguntarse: ¿los cabildantes terratenientes apoyaron la gesta sanmartiniana por convicción, o se vieron forzados a hacerlo por la imposición de un grupo en el poder? ¿Representó Santos Ortiz el proyecto de lo que el grupo terrateniente buscaba y no pudo obtener mientras se llevaba delante el plan sanmartiniano? En este trabajo se busca comparar los objetivos primarios de ambos gobernadores durante sus mandatos, con el fin de vislumbrar cuál de los planes de gobierno representaba los ideales y necesidades de los grandes terratenientes de la ciudad de San Luis.

  6. Provencance of the late Proterozoic to early Cambrian metaclastic sediments ot the Sierra de San Luis (Eastern Sierras Pampeanas) and Cordillera Oriental, Argentina

    DEFF Research Database (Denmark)

    Drobe, M.; López de Luchi, M.; Steenken, A.

    2009-01-01

    Provenance studies have been performed utilising major and trace elements, Nd systematics, whole rock Pb-Pb isotopes and zircon U/Pb SHRIMP data on metasedimentary rocks of the Sierra de San Luis (Nogolí Metamorphic Complex, Pringles Metamorphic Complex, Conlara Metamorphic Complex and San Luis...... is depicted for all the complexes using major and trace elements. The Pringles Metamorphic Complex shows indications for crustal recycling, pointing to a bimodal provenance. Major volcanic input has to be rejected due to Th/Sc, Y/Ni and Cr/V ratios for all units. The eNd(540 Ma) data is lower for the San Luis...... Formation and higher for the Conlara Metamorphic Complex, as compared to the other units, in which a good consistency is given. This is similar to the TDM ages, where the metapsammitic samples of the San Luis Formation are slightly older. The spread of data is largest for the Pringles Metamorphic Complex...

  7. Luis Ramiro Beltrán: Semblanza de un comunicador vanguardista

    Directory of Open Access Journals (Sweden)

    Alfonso Gumucio Dagron

    2009-03-01

    Full Text Available Luis Ramiro Beltrán es un "WAKIKI" investigador de seriedad académica reconocida, pensador que ha dado un aporte significativo a los estudios sobre la comunicación para el desarrollo en América Latina son frases de Alfonso Gumucio al hacer una semblanza de Beltrán en la que destaca su generosidad, apertura tolerancia y colaboración, amigo fiel, constante e incondicional y su creatividad.

  8. Entre la escasez y la inundación. Manejo del agua en la ciudad de San Luis Potosí, 1776-1888.

    Directory of Open Access Journals (Sweden)

    Yuritzi Hernández Fuentes

    2014-06-01

    Full Text Available This paper studies the historic connection between the hydric resources of the city of San Luis Potosí and their population during the XIX century, in special the management residual water and pluvial, and describing the demand for agricultural use, sanitation conflicts, systems of canalization failed to serve to water needs and also the population vulnerability to the floods. All this was result of the transformation of the system hydric of the catchment area and society actions to water use and this originated problems with water scarcity and floods that existed years before.

  9. De la BLAA: Exposición en la Biblioteca Luis Angel Arango

    Directory of Open Access Journals (Sweden)

    Juan Camilo Sierra

    2001-01-01

    Full Text Available Hasta febrero de 2003 la Biblioteca Luis Ángel Arango exhibirá una de las muestras más representativas del arte religioso internacional: 500 años de arte ruso. Iconos de la Galería Tretyakof de Moscú. Publicamos algunos apartes del plegable que acompaña la muestra.

  10. Transient electromagnetic mapping of clay units in the San Luis Valley, Colorado

    Science.gov (United States)

    Fitterman, David V.; Grauch, V.J.S.

    2010-01-01

    Transient electromagnetic soundings were used to obtain information needed to refine hydrologic models of the San Luis Valley, Colorado. The soundings were able to map an aquitard called the blue clay that separates an unconfined surface aquifer from a deeper confined aquifer. The blue clay forms a conductor with an average resistivity of 6.9 ohm‐m. Above the conductor are found a mixture of gray clay and sand. The gray clay has an average resistivity of 21 ohm‐m, while the sand has a resistivity of greater than 100 ohm‐m. The large difference in resistivity of these units makes mapping them with a surface geophysical method relatively easy. The blue clay was deposited at the bottom of Lake Alamosa which filled most of the San Luis Valley during the Pleistocene. The geometry of the blue clay is influenced by a graben on the eastern side of the valley. The depth to the blue clay is greater over the graben. Along the eastern edge of valley the blue clay appears to be truncated by faults.

  11. “Candidatus Rickettsia andeanae” en Amblyomma tigrinum, San Luis, Argentina

    Directory of Open Access Journals (Sweden)

    Gabriel CICUTTIN

    2016-11-01

    Full Text Available El objetivo del estudio fue detectar especies del género Rickettsia en garrapatas de la especie Amblyomma tigrinum colectadas sobre carnívoros domésticos y en sangre de caninos domésticos de la provincia de San Luis (Argentina. Entre 2013 y 2015 se colectaron 56 garrapatas adultas de la especie A. tigrinum sobre caninos y felinos domésticos, y se obtuvieron 65 muestras sanguíneas de caninos. Tres garrapatas resultaron positivas mediante la amplificación de un fragmento del espacio intergénico 23S-5S ARNr del género Rickettsia, lográndose secuenciar uno de los productos positivos. La muestra positiva secuenciada también resultó positiva por PCRs de los fragmentos de los genes gltA y ompA. Las secuencias obtenidas resultaron tener una identidad del 100 % de identidad con “Candidatus Rickettsia andeanae”. Todas las muestras sanguíneas resultaron negativas. “Ca. R. andeanae” no ha sido asociada con enfermedad en humanos o animales, sin embargo, es necesario realizar nuevas investigaciones para lograr un mayor conocimiento del riesgo potencial de transmisión de rickettsiosis en la región. SUMMARY. “Candidatus Rickettsia andeanae” in Amblyomma tigrinum ticks from San Luis (Argentina. The aim of this study was to detect species of Rickettsia in Amblyomma tigrinum ticks collected from domestic carnivores and blood of domestic dogs of San Luis (Argentina. Between 2013 and 2015, 56 adults of A. tigrinum from dogs and cats and 65 blood from dogs were collected. Three ticks were positive by amplification of a 23S-5S rRNA fragment, and the sequence of one of the positive products was obtained. The positive sample sequenced was positive by PCRs of fragments of genes gltA and ompA. The sequences obtained were 100% identical with "Candidatus Rickettsia andeanae". All blood samples were negative. “Ca. R. andeanae” has not been associated with disease in humans or animals; however, further research is necessary to achieve greater

  12. El pachuco entre Octavio Paz y el trayecto para su reinvención en "Zoot Suit" de Luis Valdez

    OpenAIRE

    Ochoa, Edna

    2010-01-01

    This article focuses on the figure of the pachuco in the play Zoot Suit by Luis Valdez in order to explore the most important aspects about this character. To achieve this purpose I will examine its representation in various literary texts and I will trace its history to show how the projection of the character changes from the Chicano movement in the 6os. This character is seen in a positive and memorable way, especially in the play Zoot Suit by Luis Valdez, who regards him as...

  13. Prevalence and spatial distribution of bovine brucellosis in San Luis and La Pampa, Argentina.

    Science.gov (United States)

    Aznar, M N; Linares, F J; Cosentino, B; Sago, A; La Sala, L; León, E; Duffy, S; Perez, A

    2015-08-15

    Bovine brucellosis (BB) is a zoonotic disease caused by Brucella abortus. BB is endemic in Argentina, where vaccination with Brucella abortus strain 19 is compulsory for 3-to-8 month-old heifers. The objectives of this study were to quantify the prevalence of BB and to identify factors associated with its occurrence, along with the spatial distribution of the disease, in the provinces of La Pampa and San Luis. A two-stage random sampling design was used to sample 8,965 cows (3,513 in La Pampa and 5,452 in San Luis) from 451 farms (187 in La Pampa and 264 in San Luis). Cow and herd prevalence were 1.8 % (95 % CI: 1.3-2.2; n = 157) and 19.7 % (95 % CI: 17.0-22.4; n = 89), respectively. Both cow-level and herd-level prevalence in La Pampa (2.4 and 26.0 %, respectively) were significantly higher than in San Luis (1.4 and 15.5 %, respectively). There were not differences between the proportions of reactive cattle compared to that obtained in a survey conducted in 2005. However, herd prevalence in La Pampa was significantly (P < 0.05) higher compared to that study. Disease was found to be spatially clustered in west La Pampa. The lower the bovine density and the calf/cow ratio, the higher odds of belonging to the cluster. The increase of farm prevalence in the last five years suggests that the disease is spreading and that control measures should be applied in the region. The cluster of infected farms was located in the west region of La Pampa. There, farms have lower animal densities and smaller cow/calf indices compared to the rest of the province. Although western La Pampa has more infected herds, within-farm prevalence was not higher, which suggests that the control program has been relatively successful in controlling the disease at the farm level, and/or that low animal density inherently results in low disease prevalence. Our results provide baseline information on the epidemiology of BB and its potential pattern of transmission in Argentina, which will ultimately

  14. Discovery of the neutron (to the fiftieth anniversary of neutron discovery)

    International Nuclear Information System (INIS)

    Pasechnik, M.V.

    1984-01-01

    Development of neutron physics in the USSR for the recent 50 years from the moment of neutron discovery is considered. History of neutron discovery is presented in brief. Neutron properties and fundamental problems of physics: electric dipole neutron moment, neutron β-decay, neutron interaction with nuclei and potential of nucleon interaction not conserving spatial parity are discussed. Main aspects of neutron physics application in power engineering, nuclear technology and other branches of science and technique are set forth

  15. Sm-Nd, Rb-Sr and K-Ar age constraints of the El Molle and Barroso plutons, western Sierra de San Luis, Argentina

    International Nuclear Information System (INIS)

    Sato, A.M.; Gonzalez, P.D; Petronilho, L.A; Llambias, E.J.; Varela, R; Basei, M.A.S

    2001-01-01

    Within the Early Paleozoic Famatinian orogeny of Southern Sierras Pampeanas (Sierra de San Luis and Sierra de Cordoba), the post-orogenic granitoids are characterized by circular intrusions. The published Rb-Sr and K-Ar ages from plutons in the Sierra de San Luis range between 408 and 320 Ma (see synthesis in Llambias et al., 1998). The El Molle and Barroso plutons (Sims et al., 1997; Gonzalez and Sato, 2000) are the two main exposures of a post-orogenic intrusive complex located in the western area of the Sierra de San Luis basement. They also exhibit an overall circular map view of almost 8 km in diameter, and are emplaced in a metamorphic complex developed through pre-Famatinian (Proterozoic? to Early Paleozoic) to Famatinian (Early Paleozoic) orogenies (Gonzalez and Llambias, 1998; von Gosen and Prozzi, 1998). We are carrying out isotopic datings of the El Molle and Barroso plutons in order to contribute to the understanding of the magmatic and metamorphic evolution of the final stages of the Famatinian orogenic cycle in the Sierra de San Luis. The first results of the Sm-Nd, Rb-Sr and K-Ar dates are here presented (au)

  16. Upper Holocene in a profile:tectonic depression of Conlara-Sierra de San Luis, San Luis, Argentina

    International Nuclear Information System (INIS)

    Strasser, E.; Chiesa, J.

    2004-01-01

    The characteristics of three column profiles belonging to eolic sediments, assignated to Upper Holocene of the Depression of Conlara and oriental edge of San Luis range, comprising loessic materials and sandy loessoides, associated to aluvio-eolic and pedogenetic levels are texturally described. Lineal graphics of expression are used to visualize the textual variations according to the deph, those graphics are built according to the curve of frequency accumulated of the distribution of the size, using the parameters of rank in phi (Q) intervals and the half diameter expressed in microns. The interpretation of the succession in ecuatorial direction allows the inferences of the decrease of the size of grain from the planicie (on the east) towards the mountain region (on the west). The values of parameters of rank and statistiral parameters are presented, of all the succession although it is proposed that the Upper Holocene corresponds to the two upper meters [es

  17. Ampliación de la distribución de Physalaemus biligonigerus (Cope, 1860 (Anura: Leiuperidae en la provincia de San Luis, Argentina

    Directory of Open Access Journals (Sweden)

    Moreno, Liliana

    2008-03-01

    Full Text Available República Argentina, San Luis, Departamento Gral. Pedernera, Villa Mercedes (33º42'18,71" S 66º26'27,98" W. Fecha de colección: 29/XII/ 2006. Col: R. Gutierrez y L. Moreno. Los ejemplares están depositados en la Colección Herpetológica de la Universidad Nacional de San Luis (CH-UNSL 0389 – CH-UNSL 0390.

  18. Representation Discovery using Harmonic Analysis

    CERN Document Server

    Mahadevan, Sridhar

    2008-01-01

    Representations are at the heart of artificial intelligence (AI). This book is devoted to the problem of representation discovery: how can an intelligent system construct representations from its experience? Representation discovery re-parameterizes the state space - prior to the application of information retrieval, machine learning, or optimization techniques - facilitating later inference processes by constructing new task-specific bases adapted to the state space geometry. This book presents a general approach to representation discovery using the framework of harmonic analysis, in particu

  19. Problem Formulation in Knowledge Discovery via Data Analytics (KDDA) for Environmental Risk Management.

    Science.gov (United States)

    Li, Yan; Thomas, Manoj; Osei-Bryson, Kweku-Muata; Levy, Jason

    2016-12-15

    With the growing popularity of data analytics and data science in the field of environmental risk management, a formalized Knowledge Discovery via Data Analytics (KDDA) process that incorporates all applicable analytical techniques for a specific environmental risk management problem is essential. In this emerging field, there is limited research dealing with the use of decision support to elicit environmental risk management (ERM) objectives and identify analytical goals from ERM decision makers. In this paper, we address problem formulation in the ERM understanding phase of the KDDA process. We build a DM³ ontology to capture ERM objectives and to inference analytical goals and associated analytical techniques. A framework to assist decision making in the problem formulation process is developed. It is shown how the ontology-based knowledge system can provide structured guidance to retrieve relevant knowledge during problem formulation. The importance of not only operationalizing the KDDA approach in a real-world environment but also evaluating the effectiveness of the proposed procedure is emphasized. We demonstrate how ontology inferencing may be used to discover analytical goals and techniques by conceptualizing Hazardous Air Pollutants (HAPs) exposure shifts based on a multilevel analysis of the level of urbanization (and related economic activity) and the degree of Socio-Economic Deprivation (SED) at the local neighborhood level. The HAPs case highlights not only the role of complexity in problem formulation but also the need for integrating data from multiple sources and the importance of employing appropriate KDDA modeling techniques. Challenges and opportunities for KDDA are summarized with an emphasis on environmental risk management and HAPs.

  20. Problem Formulation in Knowledge Discovery via Data Analytics (KDDA) for Environmental Risk Management

    Science.gov (United States)

    Li, Yan; Thomas, Manoj; Osei-Bryson, Kweku-Muata; Levy, Jason

    2016-01-01

    With the growing popularity of data analytics and data science in the field of environmental risk management, a formalized Knowledge Discovery via Data Analytics (KDDA) process that incorporates all applicable analytical techniques for a specific environmental risk management problem is essential. In this emerging field, there is limited research dealing with the use of decision support to elicit environmental risk management (ERM) objectives and identify analytical goals from ERM decision makers. In this paper, we address problem formulation in the ERM understanding phase of the KDDA process. We build a DM3 ontology to capture ERM objectives and to inference analytical goals and associated analytical techniques. A framework to assist decision making in the problem formulation process is developed. It is shown how the ontology-based knowledge system can provide structured guidance to retrieve relevant knowledge during problem formulation. The importance of not only operationalizing the KDDA approach in a real-world environment but also evaluating the effectiveness of the proposed procedure is emphasized. We demonstrate how ontology inferencing may be used to discover analytical goals and techniques by conceptualizing Hazardous Air Pollutants (HAPs) exposure shifts based on a multilevel analysis of the level of urbanization (and related economic activity) and the degree of Socio-Economic Deprivation (SED) at the local neighborhood level. The HAPs case highlights not only the role of complexity in problem formulation but also the need for integrating data from multiple sources and the importance of employing appropriate KDDA modeling techniques. Challenges and opportunities for KDDA are summarized with an emphasis on environmental risk management and HAPs. PMID:27983713

  1. San Luis Valley - Taos Plateau Landscape-Level Cultural Heritage Values and Risk Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Wescott, Konstance L. [Argonne National Lab. (ANL), Argonne, IL (United States); Abplanalp, Jennifer M. [Argonne National Lab. (ANL), Argonne, IL (United States); Brown, Jeff [Bureau of Land Management, Monte Vista, CO (United States); Cantwell, Brian [Argonne National Lab. (ANL), Argonne, IL (United States); Dicks, Merrill [Bureau of Land Management, Taos, NM (United States); Fredericks, Brian [Bureau of Land Management, Monte Vista, CO (United States); Krall, Angie [US Forest Service, Creede, CO (United States); Rollins, Katherine E. [Argonne National Lab. (ANL), Argonne, IL (United States); Sullivan, Robert [Argonne National Lab. (ANL), Argonne, IL (United States); Valdez, Arnie [Univ. of New Mexico, Albuquerque, NM (United States); Verhaaren, Bruce [Argonne National Lab. (ANL), Argonne, IL (United States); Vieira, Joseph [Bureau of Land Management, Monte Vista, CO (United States); Walston, Lee [Argonne National Lab. (ANL), Argonne, IL (United States); Zvolanek, Emily A. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-10-01

    The San Luis Valley – Taos Plateau Landscape-Level Cultural Heritage Values and Risk Assessment (hereafter referred to as cultural assessment) is a BLM pilot project designed to see whether the Rapid Ecoregional Assessment (REA) framework (already established and implemented throughout many ecoregions in the West) can be applied to the cultural environment.

  2. La prisión de Fray Luis

    Directory of Open Access Journals (Sweden)

    Victor Sánchez Montenegro

    1960-11-01

    Full Text Available Es una creencia general difundida por muchas historias de la literatura española y universal de que la principal causa de la prisión de Fray Luis de León en Valladolid por la Inquisición de esa ciudad, fue el haber traducido el Cantar de los Cantares, atribuidoa Salomón , es decir el Sir hassirim que los LXX tradujeron al griego Aisma Aismaton, y el Cantica Canticorum de la Vulgata. Sin embargo, como  pasaré a demostrar, no fue esa precisamente la causa de la tremenda injusticia sino otras presentarlas por sus enemigos , quienes en sus ataques hasta llegaron a probar que no descendía de Cristianos viejos sino que tenía sangre de judíos.

  3. Puelles romero, Luis: Honoré Daumier: la risa republicana

    Directory of Open Access Journals (Sweden)

    Óscar Ortega Ruiz

    2015-01-01

    Full Text Available Recientemente, Abada Editores ha puesto a disposición de sus lectores el nuevo ensayo de Luis Puelles Romero, titular de Estética y Teoría de las Artes de la Universidad de Málaga. Honoré Daumier: la risa republicana se interna en la vida y la obra de este marsellés nacido en 1808 y muerto en París en 1879, cuyo trabajo se desarrolló durante cincuenta años decisivos de la historia de Francia, desde el final del periodo legitimista hasta los inicios de la III República.

  4. Seroprevalencia de sífilis en mujeres embarazadas en San Luis Potosí Seroprevalence of syphilis in pregnant women in San Luis Potosí

    OpenAIRE

    Daniel E Noyola; Octavio Malacara-Alfaro; Victoria Lima-Rogel; Abraham Torres-Montes

    2006-01-01

    OBJETIVO: Determinar la seroprevalencia de sífilis en mujeres embarazadas. MATERIAL Y MÉTODOS: Encuesta seroepidemiológica en 1 857 mujeres que acudieron para la atención del parto a un hospital general de la ciudad de San Luis Potosí. RESULTADOS: Se diagnosticó sífilis en cinco (0.27%) mujeres al momento del parto. Los factores maternos asociados con una probabilidad superior de presentar sífilis incluyeron mayor edad materna, mayor número de embarazos previos y vivir en unión libre con su p...

  5. Abasto futuro de agua potable, análisis espacial y vulnerabilidad de la ciudad de San Luis Potosí, México

    OpenAIRE

    Contreras Servín Carlos; Galindo Mendoza María Guadalupe

    2008-01-01

    En el presente artículo se analizan y se presentan las circunstancias físicas, sociales y económicas que en conjunto afectan al panorama y a la problemática actual del abastecimiento de agua potable de la zona metropolitana de la ciudad de San Luis Potosí. Entre los temas que se abordan se encuentra la relación entre la disponibilidad del agua y el incremento de la población, así como la evolución de la extracción de aguas subterráneas. Por otra parte, la investigación muestra un diagnóstico ...

  6. The tectonic significance of K/Ar illite fine-fraction ages from the San Luis Formation (Eastern Sierras Pampeanas, Argentina)

    Science.gov (United States)

    Wemmer, Klaus; Steenken, André; Müller, Stefan; de Luchi, Mónica G. López; Siegesmund, Siegfried

    2011-04-01

    The Sierra de San Luis forms the southern tip of the Eastern Sierras Pampeanas in central Argentina. Two narrow belts of low-grade phyllites and quartz arenites, i.e. the San Luis Formation, have accommodated part of the strain-related differential exhumation of the medium- to high-grade metamorphic domains that constitute to the basement complex of the sierra. Eleven phyllite samples were subjected to the K/Ar fine-fraction dating technique. Results are interpreted in relation to the Kübler index of the illites, which indicate epimetamorphic conditions for the majority of the samples. Obtained ages between 330 and 290 Ma cover a period of compressional tectonics in the late Mississippian (Visean/Serpukhovian boundary) followed by the subsidence during the formation of the Paganzo Basin in the provinces of La Rioja and San Luis. These tectonic movements are coincident with the Toco orogeny in northern Chile and southern Bolivia. This suggests that the older K/Ar ages document the compressional stage and that younger ages record the cooling of the basement during the subsequent extensional uplift of the basement.

  7. Concentrations of persistent organic pollutants (POPs) and heavy metals in soil from San Luis Potosí, México.

    Science.gov (United States)

    Perez-Vazquez, Francisco Javier; Flores-Ramirez, Rogelio; Ochoa-Martinez, Angeles Catalina; Orta-Garcia, Sandra Teresa; Hernandez-Castro, Berenice; Carrizalez-Yañez, Leticia; Pérez-Maldonado, Iván N

    2015-01-01

    The aim of this study was to assess the levels of polybrominated diphenyl ethers (PBDEs), polychlorinated biphenyls (PCBs), p,p'-dichlorodiphenyltrichloroethane (DDT), p,p'-dichlorodiphenyldichloroethylene (DDE), and four heavy metals (arsenic, cadmium, lead, and mercury) in soil from the city of San Luis Potosí in Mexico. In order to confirm the presence of the previously mentioned compounds, outdoor surface soil samples were collected and analyzed by gas chromatography/mass spectrometer for PBDEs, PCBs, DDT, and DDE. Meanwhile, heavy metals were quantified using the atomic absorption spectrophotometry technique. The total PBDEs levels ranged from 5.0 to 134 μg/kg dry weight (dw), with a total mean PBDEs level of 22.0 ± 32.5 μg/kg dw (geometric mean ± standard deviation). For PCBs, the total mean level in the studied soil was 21.6 ± 24.7 μg/kg dw (range, Luis Potosí, Mexico, and considering that soil is an important pathway of exposure for people, a biomonitoring program for the surveillance of the general population in the city of San Luis Potosi is necessary.

  8. Relación del entrenamiento, capacitación y financiamiento con el crecimiento sostenido de pequeñas empresas del sector industrial en la ciudad de San Luis Potosí, México.

    Directory of Open Access Journals (Sweden)

    Mario Alberto Martínez Rojas

    2008-05-01

    Full Text Available The research does an analysis about the sustainable growth challenge´s in relation with the independents variables of the small business in front the context of the economic globalization, the issue of the sustainable growth, the characterization statistic and the empiric´s studies, and fi nally the analysis of the smalls business of the San Luis Potosi. It was realized a statistic study with a sample comprehend with 30 companies. The most relevant discoveries is that the managers possess enough knowledge as much academic as experience, this demonstrate that those variables are a critical factor to the sustainable growth of the small business, in the other hand the fi nancing is not a determinant factor.

  9. Fossil content and structural relationships of the San Luis zone and the Caborca zone of NW Sonora, Mexico, suppression of the precambrian Z of Caborca

    International Nuclear Information System (INIS)

    Radelli, Luigi; Solis Weiss, Vivianne; Dorame Navarro, Miguel; De La Cruz Ortega, Lissette del Carmen; Urrutia, Jose

    2008-01-01

    In the Caborca region of western Sonora a Precambrian Z does not cover a unique Precambrian socle as previously believed. Two tectonic zones occur there instead: the San Luis Zone and the Caborca Zone. The first is comprised of the Precambrian San Luis socle of gneiss and granite, crossed by 1.1 Ga old anorthosites, the San Luis sedimentary cover, and, above it, a Lower Jurassic volcano-sedimentary sequence. The Caborca Zone consists of the Precambrian Bamori socle of parametamorphic rocks crossed by 1.1 Ga old Aibo granite, and of the Gamuza sedimentary cover. 1.1 Ga ago the two zones were far away from each other. They have been brought together by the Nevadian orogeny. Both zones are allochthonous, and the Caborca Zone is a nappe upon the San Luis Zone. The lowermost units of the Gamuza cover furnished psammocorals and a possible Pterophyllum jageri (?). Accordingly, its geological age is either Palaeozoic or Triassic.The San Luis cover furnished Nematophites [Prototaxites (?) and Nematothallus] from its lower part; Calcispongiae, Cardaicarpus' seeds, and Artisia from its upper part Thus, it is a Devono-Carboniferous unit. The study area belongs in the Baja-Borderland block, which underwent, an Eocene northwards drifting of about 900 - 1000 km, and a 30 celsius degrade to 40 celsius degrade clockwise rotation relative to the main part of Sonora.

  10. Semantic Service Discovery Techniques for the composable web

    OpenAIRE

    Fernández Villamor, José Ignacio

    2013-01-01

    This PhD thesis contributes to the problem of resource and service discovery in the context of the composable web. In the current web, mashup technologies allow developers reusing services and contents to build new web applications. However, developers face a problem of information flood when searching for appropriate services or resources for their combination. To contribute to overcoming this problem, a framework is defined for the discovery of services and resources. In this framework, thr...

  11. Problem Formulation in Knowledge Discovery via Data Analytics (KDDA for Environmental Risk Management

    Directory of Open Access Journals (Sweden)

    Yan Li

    2016-12-01

    Full Text Available With the growing popularity of data analytics and data science in the field of environmental risk management, a formalized Knowledge Discovery via Data Analytics (KDDA process that incorporates all applicable analytical techniques for a specific environmental risk management problem is essential. In this emerging field, there is limited research dealing with the use of decision support to elicit environmental risk management (ERM objectives and identify analytical goals from ERM decision makers. In this paper, we address problem formulation in the ERM understanding phase of the KDDA process. We build a DM3 ontology to capture ERM objectives and to inference analytical goals and associated analytical techniques. A framework to assist decision making in the problem formulation process is developed. It is shown how the ontology-based knowledge system can provide structured guidance to retrieve relevant knowledge during problem formulation. The importance of not only operationalizing the KDDA approach in a real-world environment but also evaluating the effectiveness of the proposed procedure is emphasized. We demonstrate how ontology inferencing may be used to discover analytical goals and techniques by conceptualizing Hazardous Air Pollutants (HAPs exposure shifts based on a multilevel analysis of the level of urbanization (and related economic activity and the degree of Socio-Economic Deprivation (SED at the local neighborhood level. The HAPs case highlights not only the role of complexity in problem formulation but also the need for integrating data from multiple sources and the importance of employing appropriate KDDA modeling techniques. Challenges and opportunities for KDDA are summarized with an emphasis on environmental risk management and HAPs.

  12. Emma Zunz by Jorge Luis Borges: the Concept of Justice

    OpenAIRE

    Rosa Vila

    2014-01-01

    Emma Zunz, by Jorge Luis Borges, is the story of a girl who decides to kill her boss in order to avenge her father’s death, believing that her father’s version of an event that occurred years before was true. Thus, she devises a secret plan, which includes losing her virginity to a complete stranger, shortly before committing the crime, so she could argue that her boss had raped her and that she killed him in self-defense. Firstly, the text shows the contrast between formal justic...

  13. Entrevista con Luis Ramiro Beltrán Salmón

    Directory of Open Access Journals (Sweden)

    Fanny Patricia Franco Chávez

    2011-01-01

    Full Text Available Luis Ramiro Beltrán es un personaje obligado a la hora de hablar de la relación entre la comunicación y el desarrollo. En la siguiente entrevista, conocemos la génesis de este campo a través de un personaje que nos comparte su perfil como pionero y sus experiencias iniciales en Latinoamérica para acercarnos a las primeras definiciones de este campo y a lo que debe ser esencial en la formación del perfil de un comunicador para el desarrollo social.

  14. El ensayo de interpretación del ser nacional: su problemática y el caso de 'Nosotros' de Luis López de Mesa

    Directory of Open Access Journals (Sweden)

    Juan Camilo Galeano

    2015-01-01

    Full Text Available Este texto se divide en dos partes: la primera aborda el ensayo de interpretación del ser nacional, las voces que lo han desarrollado en América Latina y cuestiona la falta de reconocimiento de este género en Colombia. La segunda considera a Luis López de Mesa: partiendo de su obra De cómo se ha formado la nación colombiana, analiza las estrategias literarias de las que éste se vale en Nosotros para mostrar la identidad antioqueña como resultado de una debacle moral. En el desarrollo del análisis se encuentra que la industrialización de Antioquia hizo mundanos su valores humanos.

  15. Missionary Pragmalinguistics: Father Diego Luis de Sanvitores’ grammar within the tradition of Philippine grammars

    NARCIS (Netherlands)

    Winkler, A.P.

    2016-01-01

    The grammar written in Latin, in 1668, by the Jesuit missionary Father Diego Luis de Sanvitores (1627-1672) is the oldest description we have of Chamorro, a language spoken on the Mariana islands. The grammar received a number of bad reviews and as a consequence has become neglected and almost

  16. Luis Llach : el arquitecto de Quibdó

    Directory of Open Access Journals (Sweden)

    Luis Fernando González Escobar

    1993-09-01

    Full Text Available En el año 1907, en varias ediciones del periódico Ecos del Chocó, de la ciudad de Quibdó, apareció un anuncio en donde un tal Luis Llach Ll., ostentando el título de ingeniero civil, ofertaba sus servicios para la "Construcción de toda clase de edificios, Levantamientos de planos. elaboración de presupuestos, etc. y toda lo concerniente al ramo de ingeniería, contando para el efecto con instrumentos modernos y personal idóneo" ¿La dirección? El lado sur del Convento. ¿Quién era este "ingeniero" y cuáles eran las razones que lo condujeron a establecerse en una localidad que por esos años no era más que un villorrio con algo menos de 12.000 habitantes?

  17. Reduced blood nrf-2 mRNA in local overweight boys at risk of metabolic complications: a study in San Luis City, San Luis, Argentina.

    Science.gov (United States)

    Santillán, Lucas D; Moyano, Marta; Frau, Martín; Flores, Orlando; Siewert, Susana; Zirulnick, Fanny; Ramirez, Dario C; Giménez, Maria S

    2013-10-01

    Childhood overweight (OW) is a matter of public health concern because of its long-term impact on adulthood health. NF-E2-related factor 2 (Nrf-2) regulates the antioxidant/lipogenic response to a sustained positive energy balance that prevails during weight gain. Here we aimed at studying a possible link between OW and Nrf-2-dependent antioxidant/lipogenic response in a local population of boys at risk of metabolic complications. We measured clinical and biochemical parameters related to lipid metabolism, oxidative stress, and metabolic syndrome in a population of OW boys [body mass index (BMI) percentile ≥85(th) and Luis City, San Luis, Argentina. Compared to NW, OW boys had lower insulin sensitivity, an altered plasma lipid profile, and increased markers of oxidative stress and inflammatory fatty acids. OW boys also had a higher atherogenic index and peripheral insulin resistance than NW boys. We also found that glutathione peroxidase activity and the reduced glutathione to oxidized glutathione ratio were lower in OW boys than NW boys, suggesting that OW boys may have an altered antioxidant response to oxidative stress. Finally, Nrf-2 expression negatively correlated with metabolic syndrome parameters in OW boys. Our data suggest that OW boys have a reduced antioxidant and lipogenic response to a positive energy balance, resulting in oxidative stress, insulin resistance, and risk of developing metabolic complications. Our data also provide a rationale for nutritional interventions aimed at restoring Nrf-2 expression to reduce the risk of metabolic complications in OW boys.

  18. Behemoth, Lilith e Anjos: três monstros judaicos em Jorge Luis Borges

    Directory of Open Access Journals (Sweden)

    Marcos Fábio de Faria

    2009-10-01

    Full Text Available Análise dos verbetes de monstros judaicos recriados por Jorge Luis Borges em Manual de zoologia fantástica e O livro dos seres imaginários, a saber: Behemoth, Lilith e os anjos Haniel, Kazfiel, Azriel e Aniel. As múltiplas representações e versões desses verbetes, bem como seu diálogo com a Torah e sua inscrição na literatura.

  19. Juizados Especiais e Ativismo Judicial à Luz de Luis Alberto Warat

    Directory of Open Access Journals (Sweden)

    Zenildo Bodnar

    2012-07-01

    Full Text Available This article addresses, in a punctual way, some reflections on the judicial activism in the Special Courts camp. It seeks to evaluate the existence of a place for the conciliator in the stir that permeates the procedural and substantial models of legal proceedings. For this, as theoretical references, the postulates of Luis Alberto Warat are used, in order to overcome such dyad in favor of an effective judicial protection, without following the ways of the Free Movement of Law and Instrumentality of Process. For the development of this research, it has been used the inductive method, operated by the operational concepts and techniques of literature.Resumo: O presente artigo aborda de forma pontual algumas reflexões sobre o ativismo judicial na seara dos Juizados Especiais. Procura-se avaliar a existência de um lugar para o conciliador na celeuma que permeia os modelos procedimentalistas e substancialistas de processo jurisdicional. Para tanto, como referencial teórico utiliza-se os postulados de Luis Alberto Warat no intuito de superar a referida díade em favor de uma tutela judicial efetiva, sem que se trilhe os caminhos do Movimento do Direito Livre e da Instrumentalidade do Processo. Utilizou-se, para o desenvolvimento desta pesquisa, o método indutivo, operacionalizado pelas técnicas de conceitos operacionais e da pesquisa bibliográfica.

  20. Integration of Problem-Based Learning and Web-Based Multimedia to Enhance Soil Management Course

    Science.gov (United States)

    Strivelli, R.; Krzic, M.; Crowley, C.; Dyanatkar, S.; Bomke, A.; Simard, S.; Grand, S.

    2012-04-01

    In an attempt to address declining enrolment in soil science programs and the changing learning needs of 21st century students, several universities in North America and around the world have re-organized their soil science curriculum and adopted innovative educational approaches and web-based teaching resources. At the University of British Columbia, Canada, an interdisciplinary team set out to integrate teaching approaches to address this trend. The objective of this project was to develop an interactive web-based teaching resource, which combined a face-to-face problem-based learning (PBL) case study with multimedia to illustrate the impacts of three land-uses on soil transformation and quality. The Land Use Impacts (LUI) tool (http://soilweb.landfood.ubc.ca/luitool/) was a collaborative and concentrated effort to maximize the advantages of two educational approaches: (1) the web's interactivity, flexibility, adaptability and accessibility, and (2) PBL's ability to foster an authentic learning environment, encourage group work and promote the application of core concepts. The design of the LUI case study was guided by Herrington's development principles for web-based authentic learning. The LUI tool presented students with rich multimedia (streaming videos, text, data, photographs, maps, and weblinks) and real world tasks (site assessment and soil analysis) to encourage students to utilize knowledge of soil science in collaborative problem-solving. Preliminary student feedback indicated that the LUI tool effectively conveyed case study objectives and was appealing to students. The resource is intended primarily for students enrolled in an upper level undergraduate/graduate university course titled Sustainable Soil Management but it is flexible enough to be adapted to other natural resource courses. Project planning and an interactive overview of the tool will be given during the presentation.

  1. Luis Huerta: eugenesia, medicina y pedagogía en España Luis Huerta: Eugenics, Medicine and Pedagogy in Spain

    Directory of Open Access Journals (Sweden)

    Luis Miguel LÁZARO LORENTE

    2013-07-01

    Full Text Available En contraste con lo observable en la historiografía de otros países europeos y anglosajones, el estudio de la introducción y difusión de los principios y prácticas de la Eugenesia, como tema de investigación, no ha contado en España con muchos cultivadores. Menos todavía han sido objeto de estudio las relaciones del pensamiento eugénico con el ámbito pedagógico para indagar la recepción que tiene entre el Magisterio, y conocer el conjunto de reacciones que provoca, así como la participación de los maestros en la potencial difusión de sus planteamientos. Se aborda aquí una aproximación a ese tema centrando el análisis en las relaciones que en la España del primer tercio del siglo XX se establecen entre Medicina, Pedagogía y Eugenesia. Para ello tomamos como referente e hilo conductor la figura y el pensamiento del maestro asturiano Luis Huerta Naves, decidido impulsor y propagandista incansable de la Eugenesia en nuestro país.By comparison with the historiography of other European and Anglo-Saxon countries, the study of the origins and spread of Eugenics in Spain has not received much attention. Even less research has been done on the degree of acceptance of eugenic thought in the pedagogical domain or on the role teachers may have in the diffusion of eugenics. This paper attempts to explore the subject while focusing the analysis on the relations that were established among Medicine, Pedagogy and Eugenics in Spain during the first third of the 20th century. We will take as a point of reference and guiding line of thought the figure of the Asturian teacher Luis Huerta Naves, who was the driving force and tireless advocate of the eugenics movement in our country.

  2. Mesquite: A multi-purpose species in two locations of San Luis Potosi, Mexico

    Science.gov (United States)

    Jose Villanueva-Diaz; Augustin Hernandez-Reyna; J. Armando Ramirez-Garcia

    2000-01-01

    The mesquite woodland distributed in approximately 200,000 ha in Llanos de Angostura, and Pozo del Carmen, San Luis Potosi, represents a main source of firewood, construction material, honey, and forage for the rural people that inhabit part of the lowlands of the hydrological region RH26 and RH37. Firewood collection in this region averages 142 m3 /week. Most of this...

  3. ÎNCEPUTURILE FILOSOFICE ALE LUI LUCIAN BLAGA

    Directory of Open Access Journals (Sweden)

    Svetlana COANDĂ

    2016-12-01

    Full Text Available În articol sunt evidenţiate etapele evoluţiei spirituale a lui Lucian Blaga, este demonstrată importanţa primei perioade de activitate a gânditorului român, perioada anilor 1914-1919, care constituie începutul activităţii filosofice a lui L.Blaga, acesta fiind deosebit de semnificativ pentru înţelegerea genezei ideilor sale, a influenţelor pe care le-a suportat, a continuităţii tematicii şi reflecţiilor filosofice, care au culminat cu elaborarea unui profund sistem filosofic. Sunt analizate în detaliu ideile filosofice centrale, temele de meditaţie din lucrările scrise şi publicate de L.Blaga între anii 1914 şi 1919: analiza şi aprecierea ideilor filosofului francez Henri Bergson, coraportul dintre filosofie şi ştiinţă, aportul specific al filosofiei la formarea concepţiei despre lume a personalităţii, rolul deosebit de important al metodelor de cercetare în asigurarea obţinerii adevărului în procesul de cunoaştere, unitatea formelor culturii etc.THE PHILOSOFICAL BEGINNINGS OF LUCIAN BLAGAThis article highlights the spiritual evolution steps of Lucian Blaga and demonstrates the importance of the first period of activity of the Romanian thinker - the period between 1914 and 1919. This time frame constitutes the beginning of his philosophical activity and it is especially significant to understand the genesis of his ideas, of his influences, the continuity of the philosophical themes and reflections that culminated with the elaboration of a profound philosophical system. Analysis is done over the central philosophical ideas, the meditation themes from the works written and published by Lucian Blaga between 1914 and 1919: the analysis and appreciation of the ideas of the French philosopher Henri Bergson, the correlation between philosophy and science, the specific input of philosophy in the formation of the world conception on personality, the extremely important role of the research methods in ensuring the

  4. Emphatic or Reflexive? On the Endophoric Character of French "lui-meme" and Similar Complex Pronouns.

    Science.gov (United States)

    Zribi-Hertz, Anne

    1995-01-01

    This study examined the referential properties of a class of complex pronouns labelled M-Pronouns, exemplified by Old English "himself," French "lui-meme," and English "his own." It is shown that M-Pronouns exhibit some properties commonly taken as characterizing reflexive anaphors, and that they also occur as…

  5. Science of the science, drug discovery and artificial neural networks.

    Science.gov (United States)

    Patel, Jigneshkumar

    2013-03-01

    Drug discovery process many times encounters complex problems, which may be difficult to solve by human intelligence. Artificial Neural Networks (ANNs) are one of the Artificial Intelligence (AI) technologies used for solving such complex problems. ANNs are widely used for primary virtual screening of compounds, quantitative structure activity relationship studies, receptor modeling, formulation development, pharmacokinetics and in all other processes involving complex mathematical modeling. Despite having such advanced technologies and enough understanding of biological systems, drug discovery is still a lengthy, expensive, difficult and inefficient process with low rate of new successful therapeutic discovery. In this paper, author has discussed the drug discovery science and ANN from very basic angle, which may be helpful to understand the application of ANN for drug discovery to improve efficiency.

  6. Uranium occurrences in the pegmatite 'Las Cuevas', province of San Luis, Argentine Republic

    International Nuclear Information System (INIS)

    Daziano, C.O.; Karlsson, A.C.; Ayala, R.

    1993-01-01

    Mineral associations found in an uranium deposit of Sierras Pampeanas, San Luis, are considered in these papers. Damourite stands out among the uranium minerals related to uraninite and coffinite. Pyrite, marcasite and other sulphides are found together with apatite and gummite. Autunite is the uranium secondary mineral more abundant. A mineralization with epigenetic contribution by circulating solutions is suggested to the studied area. (Author)

  7. The nuclear industry is about to begin a new dynamic. Interview with Luis Echavarri

    Energy Technology Data Exchange (ETDEWEB)

    Mitev, Lubomir [NucNet, Brussels (Belgium)

    2014-05-15

    The nuclear industry has changed significantly in the 17 years since Luis Echavarri became director-general of the Organisation for Economic Development and Cooperation's (OECD) Paris-based Nuclear Energy Agency (NEA). As he approaches retirement, Mr Echavarri speaks to NucNet about the priorities for the industry as it enters the post-Fukushima era. (orig.)

  8. Mineralogical characterization of historical portuguese wall tiles of Sao Luis, Maranhao, Brazil; Caracterizacao mineralogica de azulejos portugueses do Centro Historico de Sao Luis do Maranhao

    Energy Technology Data Exchange (ETDEWEB)

    Rivas Mercury, J.M.; Vasconcelos, N.S.L.S.; Cabral, A.A., E-mail: rivascefetma@gmail.co [Instituto Federal de Educacao, Ciencia e Tecnologia do Maranhao (IFMA), Sao Luis, MA (Brazil). Programa de Mestrado em Engenharia de Materiais; Pereira, D.J. Costa [Centro de Criatividade Odylo Costa Filho (SECMA), Sao Luis, MA (Brazil). Centro Historico; Angelica, R.S. [Universidade Federal do Para (CG/UFPA), Belem, PA (Brazil). Inst. de Geociencias

    2010-07-01

    Portuguese wall tiles from centuries, XVII, XVIII and XIX, found in Sao Luis Maranhao has been studied by X-ray diffraction, in order to interpret the possible raw material and burning temperature. The mineral phases, Quartz, Wollastonite, Calcite and Gehlenite were identified in all samples. Based on the results it is possible to affirm that the main raw materials used to manufacture this materials was probably mixtures of kaolinite clay and calcite. Based on the mineralogical information it was also possible to state that burning temperature of this wall tiles was lower than 1000 deg C. (author)

  9. Luis Huerta: Eugenics, Medicine and Pedagogy in Spain

    Directory of Open Access Journals (Sweden)

    Luis Miguel LÁZARO LORENTE

    2013-11-01

    Full Text Available By comparison with the historiography of other European and Anglo-Saxon countries, the study of the origins and spread of Eugenics in Spain has not received much attention. Even less research has been done on the degree of acceptance of eugenic thought in the pedagogical domain or on the role teachers may have in the diffusion of eugenics. This paper attempts to explore the subject while focusing the analysis on the relations that were established among Medicine, Pedagogy and Eugenics in Spain during the first third of the 20th century. We will take as a point of reference and guiding line of thought the figure of the Asturian teacher Luis Huerta Naves, who was the driving force and tireless advocate of the eugenics movement in our country.

  10. Uranium series isotopes concentration in sediments at San Marcos and Luis L. Leon reservoirs, Chihuahua, Mexico

    Science.gov (United States)

    Méndez-García, C.; Renteria-Villalobos, M.; García-Tenorio, R.; Montero-Cabrera, M. E.

    2014-07-01

    Spatial and temporal distribution of the radioisotopes concentrations were determined in sediments near the surface and core samples extracted from two reservoirs located in an arid region close to Chihuahua City, Mexico. At San Marcos reservoir one core was studied, while from Luis L. Leon reservoir one core from the entrance and another one close to the wall were investigated. 232Th-series, 238U-series, 40K and 137Cs activity concentrations (AC, Bq kg-1) were determined by gamma spectrometry with a high purity Ge detector. 238U and 234U ACs were obtained by liquid scintillation and alpha spectrometry with a surface barrier detector. Dating of core sediments was performed applying CRS method to 210Pb activities. Results were verified by 137Cs AC. Resulting activity concentrations were compared among corresponding surface and core sediments. High 238U-series AC values were found in sediments from San Marcos reservoir, because this site is located close to the Victorino uranium deposit. Low AC values found in Luis L. Leon reservoir suggest that the uranium present in the source of the Sacramento - Chuviscar Rivers is not transported up to the Conchos River. Activity ratios (AR) 234U/overflow="scroll">238U and 238U/overflow="scroll">226Ra in sediments have values between 0.9-1.2, showing a behavior close to radioactive equilibrium in the entire basin. 232Th/overflow="scroll">238U, 228Ra/overflow="scroll">226Ra ARs are witnesses of the different geological origin of sediments from San Marcos and Luis L. Leon reservoirs.

  11. Uranium series isotopes concentration in sediments at San Marcos and Luis L. Leon reservoirs, Chihuahua, Mexico

    International Nuclear Information System (INIS)

    Méndez-García, C.; Montero-Cabrera, M. E.; Renteria-Villalobos, M.; García-Tenorio, R.

    2014-01-01

    Spatial and temporal distribution of the radioisotopes concentrations were determined in sediments near the surface and core samples extracted from two reservoirs located in an arid region close to Chihuahua City, Mexico. At San Marcos reservoir one core was studied, while from Luis L. Leon reservoir one core from the entrance and another one close to the wall were investigated. 232 Th-series, 238 U-series, 40 K and 137 Cs activity concentrations (AC, Bq kg −1 ) were determined by gamma spectrometry with a high purity Ge detector. 238 U and 234 U ACs were obtained by liquid scintillation and alpha spectrometry with a surface barrier detector. Dating of core sediments was performed applying CRS method to 210 Pb activities. Results were verified by 137 Cs AC. Resulting activity concentrations were compared among corresponding surface and core sediments. High 238 U-series AC values were found in sediments from San Marcos reservoir, because this site is located close to the Victorino uranium deposit. Low AC values found in Luis L. Leon reservoir suggest that the uranium present in the source of the Sacramento – Chuviscar Rivers is not transported up to the Conchos River. Activity ratios (AR) 234 U/ 238 U and 238 U/ 226 Ra in sediments have values between 0.9–1.2, showing a behavior close to radioactive equilibrium in the entire basin. 232 Th/ 238 U, 228 Ra/ 226 Ra ARs are witnesses of the different geological origin of sediments from San Marcos and Luis L. Leon reservoirs

  12. La problemática del género literario: una lectura de El río, novelas de caballería de Luis Cardoza y Aragón

    OpenAIRE

    Rodríguez Cascante, Francisco; Universidad de Costa Rica

    2013-01-01

    El presente trabajo examina brevemente, en una primera parte, las concepciones del género literario en Aristóteles, Oscar Tacca, Roberto Fernández Retamar, Hans Robert Jauss, Mijaíl Bajtín y Roland Barthes. Luego, en una segunda parte, se efectúa una discusión de esta categoría en un estudio de caso: una aproximación al texto autobiográfico El río, novelas de caballería del escritor guatemalteco Luis Cardoza y Aragón

  13. Evaluating the sustainability of a regional system using Fisher information in the San Luis Basin, Colorado

    Science.gov (United States)

    This paper describes the theory, data, and methodology necessary for using Fisher information to assess the sustainability of the San Luis Basin (SLB) regional system over time. Fisher information was originally developed as a measure of the information content in data and is an ...

  14. Green Net Regional Product for the San Luis Basin, Colorado: An Economic Measure of Regional Sustainability

    Science.gov (United States)

    This paper presents the data sources and methodology used to estimate Green Net Regional Product (GNRP), a green accounting approach, for the San Luis Basin (SLB). GNRP is equal to aggregate consumption minus the depreciation of man-made and natural capital. We measure the move...

  15. Introducción [Jorge Luis Borges : Translación e Historia

    OpenAIRE

    de Toro, Alfonso

    2015-01-01

    El presente volumen es el resultado de una selección de las ponencias presentadas en el coloquio internacional "Jorge Luis Borges: Translación e Historia" realizado con el auspicio de la Deutsche Forschungsgemeinschaft en el Centro de Investigación Iberoamericana del 4 al 9 de diciembre de 2007 y pone en el centro de su reflexión a Borges como fenómeno de "translación", entendiendo por el concepto de "translación" un complejo proceso cultural, medial, social y pragmasemiótico que abarca tanto...

  16. Master Mentors: Linda Golian-Lui University of Hawaii-Hilo--George Oberle George Mason University, VA

    Science.gov (United States)

    Library Journal, 2005

    2005-01-01

    Many movers and shakers inspire admiration and even awe, but those who inspire love are the mentors who have changed lives. That is why many grateful librarians nominated Linda Golian-Lui and George Oberle. Both of them were accidental librarians, work-study students whose supervisors encouraged them to become paraprofessionals, and then…

  17. Blue oak plant communities of southern San Luis Obispo and northern Santa Barbara Counties, California

    Science.gov (United States)

    Mark I. Borchert; Nancy D. Cunha; Patricia C. Krosse; Marcee L. Lawrence

    1993-01-01

    An ecological classification system has been developed for the Pacific Southwest Region of the Forest Service. As part of that classification effort, blue oak (Quercus douglasii) woodlands and forests of southern San Luis Obispo and northern Santa Barbara Counties in Los Padres National Forest were classified into I3 plant communities using...

  18. Luis G. Urbina: crônicas porfirianas

    Directory of Open Access Journals (Sweden)

    Miguel Angel Castro

    2015-11-01

    Full Text Available As descrições amenas de uma cidade instável, às vezes divertida e atrativa, outras, entediante e miserável, assim como a crítica de costumes de seus habitantes, abrem um espaço original à tolerância e nele se fundamenta a natureza democrática da crônica jornalística do último quarto do século XIX e se determina o prolongamento de alguns dos seus traços literários no início do século XX. Com o intuito de conservar o valor literário de origem se constrói uma poética do gênero. Neste artigo, apresentamos algumas observações feitas a esse respeito nas crônicas que Luis G. Urbina publicou em El Mundo ilustrado entre 1899 e 1906.      This work is licensed under a Creative Commons Attribution 3.0 License.

  19. Rule Induction-Based Knowledge Discovery for Energy Efficiency

    OpenAIRE

    Chen, Qipeng; Fan, Zhong; Kaleshi, Dritan; Armour, Simon M D

    2015-01-01

    Rule induction is a practical approach to knowledge discovery. Provided that a problem is developed, rule induction is able to return the knowledge that addresses the goal of this problem as if-then rules. The primary goals of knowledge discovery are for prediction and description. The rule format knowledge representation is easily understandable so as to enable users to make decisions. This paper presents the potential of rule induction for energy efficiency. In particular, three rule induct...

  20. Astroparticle physics: puzzles and discoveries

    International Nuclear Information System (INIS)

    Berezinsky, V

    2008-01-01

    Puzzles often give birth to the great discoveries, the false discoveries sometimes stimulate the exiting ideas in theoretical physics. The historical examples of both are described in Introduction and in section 'Cosmological Puzzles'. From existing puzzles most attention is given to Ultra High Energy Cosmic Ray (UHECR) puzzle and to cosmological constant problem. The 40-years old UHECR problem consisted in absence of the sharp steepening in spectrum of extragalactic cosmic rays caused by interaction with CMB radiation. This steepening is known as Greisen-Zatsepin-Kuzmin (GZK) cutoff. It is demonstrated here that the features of interaction of cosmic ray protons with CMB are seen now in the spectrum in the form of the dip and beginning of the GZK cutoff. The most serious cosmological problem is caused by large vacuum energy of the known elementary-particle fields which exceeds at least by 45 orders of magnitude the cosmological vacuum energy. The various ideas put forward to solve this problem during last 40 years, have weaknesses and cannot be accepted as the final solution of this puzzle. The anthropic approach is discussed

  1. Computational science and re-discovery: open-source implementation of ellipsoidal harmonics for problems in potential theory

    International Nuclear Information System (INIS)

    Bardhan, Jaydeep P; Knepley, Matthew G

    2012-01-01

    We present two open-source (BSD) implementations of ellipsoidal harmonic expansions for solving problems of potential theory using separation of variables. Ellipsoidal harmonics are used surprisingly infrequently, considering their substantial value for problems ranging in scale from molecules to the entire solar system. In this paper, we suggest two possible reasons for the paucity relative to spherical harmonics. The first is essentially historical—ellipsoidal harmonics developed during the late 19th century and early 20th, when it was found that only the lowest-order harmonics are expressible in closed form. Each higher-order term requires the solution of an eigenvalue problem, and tedious manual computation seems to have discouraged applications and theoretical studies. The second explanation is practical: even with modern computers and accurate eigenvalue algorithms, expansions in ellipsoidal harmonics are significantly more challenging to compute than those in Cartesian or spherical coordinates. The present implementations reduce the 'barrier to entry' by providing an easy and free way for the community to begin using ellipsoidal harmonics in actual research. We demonstrate our implementation using the specific and physiologically crucial problem of how charged proteins interact with their environment, and ask: what other analytical tools await re-discovery in an era of inexpensive computation?

  2. Making Borges. The Early Reception of Jorge Luis Borges's Work in France and the United States

    NARCIS (Netherlands)

    Wijnterp, L.

    2016-01-01

    This thesis analyzes the role of individual mediators in the early reception of the works of the Argentine writer Jorge Luis Borges (1899-1986). It focuses on a number of key mediators such as publishers, editors, translators, and critics in the translation and publication process and in criticism

  3. Black bear abundance, habitat use, and food habits in the Sierra San Luis, Sonora, Mexico

    Science.gov (United States)

    Rodrigo Sierra Corona; Ivan A. Sayago Vazquez; M. del Carmen Silva Hurtado; Carlos A. Lopez Gonzalez

    2005-01-01

    We studied black bears to determine habitat use, food habits, and abundance between April 2002 and November 2003 in the Sierra San Luis, Sonora. We utilized transects to determine spoor presence, camera traps for abundance, and scat analysis. During 2002, bears fed principally on plant material, and for 2003 on animal matter, namely livestock. Habitat use differed...

  4. Una aproximación al poema “Arte Poética” de Jorge Luis Borges

    Directory of Open Access Journals (Sweden)

    Lorena Chaves Salgado

    2013-01-01

    Full Text Available Este artículo presenta una lectura del poema 'Arte poética' de Jorge Luis Borges desarrollando aspectos teóricos relacionados con el análisis poético. El poema describe la labor del poeta y que significa escribir poesía, entendido para Borges como un acto y proceso creativo.

  5. Una aproximación al poema “Arte Poética” de Jorge Luis Borges

    Directory of Open Access Journals (Sweden)

    Lorena Chaves Salgado

    2013-01-01

    Full Text Available Este artículo presenta una lectura del poema 'Arte poética' de Jorge Luis Borges desarrollando aspectos teóricos relacionados con el análisis poético. El poema describe la labor del poeta y qué significa escribir poesía, entendido para Borges como un acto y proceso creativo.

  6. A petroleum discovery-rate forecast revisited-The problem of field growth

    Science.gov (United States)

    Drew, L.J.; Schuenemeyer, J.H.

    1992-01-01

    A forecast of the future rates of discovery of crude oil and natural gas for the 123,027-km2 Miocene/Pliocene trend in the Gulf of Mexico was made in 1980. This forecast was evaluated in 1988 by comparing two sets of data: (1) the actual versus the forecasted number of fields discovered, and (2) the actual versus the forecasted volumes of crude oil and natural gas discovered with the drilling of 1,820 wildcat wells along the trend between January 1, 1977, and December 31, 1985. The forecast specified that this level of drilling would result in the discovery of 217 fields containing 1.78 billion barrels of oil equivalent; however, 238 fields containing 3.57 billion barrels of oil equivalent were actually discovered. This underestimation is attributed to biases introduced by field growth and, to a lesser degree, the artificially low, pre-1970's price of natural gas that prevented many smaller gas fields from being brought into production at the time of their discovery; most of these fields contained less than 50 billion cubic feet of producible natural gas. ?? 1992 Oxford University Press.

  7. Marxismo y Moral. Reflexiones a partir de El marxismo como moral de José Luis López Aranguren

    Directory of Open Access Journals (Sweden)

    Muñoz, Jacobo

    2014-06-01

    Full Text Available Starting from a critical reading of El marxismo como moral, classical work of José Luis López Aranguren, this article deals with the problem of the normative and moral foundations of marxism. In order to go in depth into the ethical dimension of Karl Marx's and the marxist tradition's thought, the text proposes several thematic lines of analysis with the aim of liberating, at the same time, the intelectual and political project of Marx from the various clichés associated to its traditional reception. The ethical field will appear as a space of mediation between knowledge and reality, disclosing itself as fundamental to marxism from a praxeological point of view. At the end of the article there is a critical dialogue with different ethical positions in the frame of contemporary marxism.A partir de una lectura crítica de El marxismo como moral, obra clásica de José Luis López Aranguren, éste artículo trata de interrogarse acerca de los fundamentos normativos y morales del marxismo. A lo largo del texto se proponen diversas líneas temáticas para profundizar en la dimensión ética del pensamiento de Karl Marx y la tradición marxista, tratando de liberar, al mismo tiempo, su proyecto intelectual y político de diversos tópicos vinculados a su recepción tradicional. El ámbito ético aparecerá como espacio de mediación entre el conocimiento y la realidad, revelándose como fundamental para el marxismo desde un punto de vista praxeológico. Al final del artículo se dialoga críticamente con algunas posiciones éticas en el marco del marxismo contemporáneo.

  8. More than Meets the Eye: Adult Education for Critical Consciousness in Luis Camnitzer's Art

    Science.gov (United States)

    Zorrilla, Ana Carlina

    2012-01-01

    The purpose of this study was to explore the connection between art and adult education for critical consciousness through the conceptual art of Luis Camnitzer. The theoretical framework grounding this research was critical public pedagogy, influenced by both critical theory and Stuart Hall's systems of representation (1997). This framework…

  9. Rating the quality of the landscape of Sierra de las Quijadas National Park, Province of San Luis, Argentina

    International Nuclear Information System (INIS)

    Maero, I.; Rivarola, D.; Tognelli, G.

    2007-01-01

    The National Park Sierra de las Quijadas is located to 120 km to the northwest of the Province of San Luis, Argentina. The study area is of 24,000 hectares, that correspond to 32 % of the total surface, this surface covers the totality with the Potrero de la Aguada and the next zones, the same one was selected because it conforms at the present time the zone of greater frequency of visitors within the Park. The objective of this work is centered in the obtaining of the Total Quality of the Landscape, having compared the demand of beauty to the rest of the other natural resources, to be able to make proposals to improve the Plan of Handling that takes ahead the Administration of National Parks. The used Methodology is the described one by Cendrero et. al. (1987), it is an indirect valuation that is carried out through the components of the landscape and allows to determine the Intrinsic Visual Quality and the Fragility of each one of the Environmental Units in which the park is divided. This analysis allowed to determine 2 Total Qualities of Landscape, that have been mapped using aerial photography equipment and materials and SIG, with field control. This investigation is developed within the Project of Investigation Geology of the Neogeno and Cuaternario of the Mountain range of San Luis, Faculty of Sciences Physical, Mathematics and Natural - National University of San Luis, Argentina. (author)

  10. Las dos Celamas de Luis Mateo Díez: recuerdo y olvido

    Directory of Open Access Journals (Sweden)

    Oscar Bazán Rodríguez

    2015-02-01

    Full Text Available El artículo reflexiona sobre el tratamiento del espacio en la trilogía de Luis Mateo Díez, El reino de Celama. Con un diverso aporte teórico y crítico explica la relación intrínseca que ocurre entre el espacio y sus habitantes en la obra, y postula que implícitamente hay una separación entre dos Celamas que, a pesar de ocupar un mismo espacio, son distintas en el tiempo, y se corresponden con los valores del recuerdo (luz y del olvido (oscuridad.

  11. Yacimientos de Celestina en la Plataforma Valles-San Luis Potosí

    OpenAIRE

    Rocha Rocha, Macario

    2008-01-01

    En la zona de estudio, la Plataforma Valles-San Luis Potosí (PVSLP), existen depósitos de celestina; las características geotectónicas de la zona, hacen pensar que estos depósitos se asocian con evaporitas del Jurásico Superior-Cretácico Inferior. La mineralización de celestina arma en la Formación El Abra y en menor grado la Formación Indidura, en forma de vetas, mantos, zonas de brecha y cuerpos irregulares. La mineralogía consiste básicamente de celestina y algunos minerales...

  12. Knowledge discovery in the prediction of bankruptcy

    NARCIS (Netherlands)

    Almeida, R.J.; Vieira, S.M.; Milea, D.V.; Kaymak, U.; Costa Sousa, da J.M.; Carvalho, J.P.; Dubois, D.; Kaymak, U.

    2009-01-01

    Knowledge discovery in databases (KDD) is the process of discovering interesting knowledge from large amounts of data. However, real-world datasets have problems such as incompleteness, redundancy, inconsistency, noise, etc. All these problems affect the performance of data mining algorithms. Thus,

  13. Network-based discovery through mechanistic systems biology. Implications for applications--SMEs and drug discovery: where the action is.

    Science.gov (United States)

    Benson, Neil

    2015-08-01

    Phase II attrition remains the most important challenge for drug discovery. Tackling the problem requires improved understanding of the complexity of disease biology. Systems biology approaches to this problem can, in principle, deliver this. This article reviews the reports of the application of mechanistic systems models to drug discovery questions and discusses the added value. Although we are on the journey to the virtual human, the length, path and rate of learning from this remain an open question. Success will be dependent on the will to invest and make the most of the insight generated along the way. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Uranium series isotopes concentration in sediments at San Marcos and Luis L. Leon reservoirs, Chihuahua, Mexico

    Energy Technology Data Exchange (ETDEWEB)

    Méndez-García, C.; Montero-Cabrera, M. E., E-mail: elena.montero@cimav.edu.mx [Centro de Investigación en Materiales Avanzados, CIMAV, Miguel de Cervantes 120, 31109, Chihuahua, Chihuahua (Mexico); Renteria-Villalobos, M. [Facultad de Zootecnia y Ecología Universidad Autónoma de Chihuahua, Periferico Francisco R. Almada Km 1, 31410, Chihuahua (Mexico); García-Tenorio, R. [Applied Nuclear Physics Group, University of Seville, ETS Arquitectura, Avda. Reina Mercedes s/n, 41012 Seville (Spain)

    2008-01-01

    Spatial and temporal distribution of the radioisotopes concentrations were determined in sediments near the surface and core samples extracted from two reservoirs located in an arid region close to Chihuahua City, Mexico. At San Marcos reservoir one core was studied, while from Luis L. Leon reservoir one core from the entrance and another one close to the wall were investigated. ²³²Th-series, ²³⁸U-series, ⁴⁰K and ¹³⁷Cs activity concentrations (AC, Bq kg⁻¹) were determined by gamma spectrometry with a high purity Ge detector. ²³⁸U and ²³⁴U ACs were obtained by liquid scintillation and alpha spectrometry with a surface barrier detector. Dating of core sediments was performed applying CRS method to ²¹⁰Pb activities. Results were verified by ¹³⁷Cs AC. Resulting activity concentrations were compared among corresponding surface and core sediments. High ²³⁸U-series AC values were found in sediments from San Marcos reservoir, because this site is located close to the Victorino uranium deposit. Low AC values found in Luis L. Leon reservoir suggest that the uranium present in the source of the Sacramento – Chuviscar Rivers is not transported up to the Conchos River. Activity ratios (AR) ²³⁴U/²³⁸U and ²³⁸U/²²⁶Ra in sediments have values between 0.9–1.2, showing a behavior close to radioactive equilibrium in the entire basin. ²³²Th/²³⁸U, ²²⁸Ra/²²⁶Ra ARs are witnesses of the different geological origin of sediments from San Marcos and Luis L. Leon reservoirs.

  15. Jorge Luis Borges y Wilhem Ostwald. Notas para una alianza entre la ciencia y las humanidades

    Directory of Open Access Journals (Sweden)

    Lothar Beyer

    2011-05-01

    Full Text Available Jorge Luis Borges (1899-1986 de nacionalidad argentina, fue escritor, poeta y filósofo de fama mundial. Wilhelm Ostwald (1853-1932, de nacionalidad alemana, fue uno de los fundadores de la físicoquímica.También fue filósofo, pintor y premio Nobel de Química (1909. Los dos hombres enriquecieron el diálogo entre ciencia y humanidades gracias a sus obras y sus discursos, a pesar de que nunca se conocieron personalmente.Un simposio en la ciudad de Leipzig, en cuya universidad Wilhelm Ostwald se desempeñó durante 20 años como catedrático principal de físicoquímica, realizado en octubre de 2001, tenía el título: «Jorge Luis Borges. Ciencia y filosofía». A ese simposio el autor de este artículo contribuyó con una conferencia: «Ciencias y humanidades en diálogoconstructivo» dictada en presencia de la viuda María Kodama de Borges.

  16. Inquérito soro-epidemiológico na Ilha de São Luis durante epidemia de dengue no Maranhão Seroepidemiologic survey in São Luis Island, State of Maranhão, Brazil, during a dengue fever epidemics

    Directory of Open Access Journals (Sweden)

    Pedro Fernando da C. Vasconcelos

    1999-04-01

    Full Text Available Nos anos de 1995 e 1996, ocorreu em São Luis uma epidemia de dengue (DEN, causada pelo sorotipo DEN1. Objetivando avaliar o impacto da mesma na população da grande São Luis (municípios de Paço do Lumiar - PL, São José de Ribamar - SJR e São Luis SL, realizamos um inquérito soro - epidemiológico aleatório, onde aplicamos um questionário. Os soros foram testados por inibição da hemaglutinação (IH, e os resultados, negativo e positivo (resposta primária - RP e resposta secundária - RS, foram analisados utilizando os "software's" Lotus 123, Epi-info 6.0, Excel 5.0 e STATA. Coletaram-se 1217 amostras, (101 de PL, 100 de SJR e 1016 de SL. A positividade foi: 55,4% em PL, 28% em SJR e 41,4% em SL. Destes, 505 (41,2% amostras foram positivas sendo 96 RP (7,9% e 405 RS (33,3%. Da amostra obtida, 508 soros (227 positivos foram do sexo masculino e 709 (278 positivos do feminino, não havendo diferença estatística significativa. Houve significância (p The Island of São Luis in the State of Maranhão, constituted by the municipalities of São Luis - SL (835,428 inhabitants, São José de Ribamar - SJR (60,633 inhabitants and Paço do Lumiar - PL (80,274 inhabitants, has been suffering dengue (DEN fever epidemics since 1995, caused by DEN-1. In 1996, from August through October, an aleatory sero-epidemiologic survey was carried out in order to estimate the incidence of DEN infection and to analyze other clinical and epidemiological parameters. A questionnaire was applied and serum samples were simultaneously obtained. Serum samples were tested by hemagglutination inhibition (HI. Results were analyzed using Lotus123, Epi-info 6.0, Excel 5.0 and STATA softwares. A total of 1,217 serum samples were obtained (101 of PL, 100 of SJR and 1017 of SL. The rate of DEN was 55.4% in PL, 28% in SJR and 41.4% in SL, suggesting the occurrence of 401,933 infections. No difference was seen between males and females, but infection occurred more in the

  17. 76 FR 39091 - San Luis Obispo Flood Control and Water Conservation District; Notice of Effectiveness of Surrender

    Science.gov (United States)

    2011-07-05

    ... Flood Control and Water Conservation District; Notice of Effectiveness of Surrender On October 27, 1981... \\1\\ to the San Luis Obispo Flood Control and Water Conservation District (District) for the Lopez... and Water Conservation District, 17 FERC ] 62,113 (1981). On October 24, 2005, the District filed an...

  18. Transient Electromagnetic Soundings Near Great Sand Dunes National Park and Preserve, San Luis Valley, Colorado (2006 Field Season)

    Science.gov (United States)

    Fitterman, David V.; de Sozua Filho, Oderson A.

    2009-01-01

    Time-domain electromagnetic (TEM) soundings were made near Great Sand Dunes National Park and Preserve in the San Luis Valley of southern Colorado to obtain subsurface information of use to hydrologic modeling. Seventeen soundings were made to the east and north of the sand dunes. Using a small loop TEM system, maximum exploration depths of about 75 to 150 m were obtained. In general, layered earth interpretations of the data found that resistivity decreases with depth. Comparison of soundings with geologic logs from nearby wells found that zones logged as having increased clay content usually corresponded with a significant resistivity decrease in the TEM determined model. This result supports the use of TEM soundings to map the location of the top of the clay unit deposited at the bottom of the ancient Lake Alamosa that filled the San Luis Valley from Pliocene to middle Pleistocene time.

  19. El satisfecho: fama y fortuna de una comedia desconocida de Luis Belmonte (El satisfecho: fame and fortune of an unknown comedy by Luis Belmonte

    Directory of Open Access Journals (Sweden)

    Elisa Domínguez de Paz

    2014-01-01

    Full Text Available Resumen: Este artículo ofrece un estudio del manuscrito autógrafo de la comedia, El satisfecho, firmado por el dramaturgo Luis Belmonte en Sevilla, el 24 de Julio de 1634. El documento proporciona buena información acerca de su recorrido por el tiempo, desde que obtiene la licencia de representación en Lisboa, en 1639, hasta que aparece en Toro, en 1653, como propiedad de Santiago Manteca. El manuscrito resulta muy interesante por la gran cantidad de probationes pennae, de contenido variado y ajeno al asunto teatral, que contiene. Estos ejercicios de escritura, salidos todos ellos de la pluma de Santiago Manteca, revelan que el escribano es un hombre preocupado por el mundo documental y formulístico. Su poco interés por conservar limpio el documento indica, por un lado, que , tal vez, la comedia ya no tenía éxito y, por otro lado, la más que probable desconexión de Manteca del mundo teatral.Abstract: This article studies an autographic manuscript of the comedy, El satisfecho, signed by the playwright Luis Belmonte in Seville, on July 24 1634. The document provides sound information about its journey through time, from the moment when it obtained its representation permit in Lisbon, in 1639, until it appeared in Toro, property of Santiago Manteca. The interest of the manuscript is very high due to the great number of probationes pennae that it contains, of very varied content and unrelated to the world of theatre. These writing exercises, coming out of Santiago Manteca’s pen, reveal that the secretary was a man concerned about the documental and formulaic world. His lack of interest in keeping the document clean may indicate, on the one hand, that the comedy was not successful any more, and, on the other, Manteca’s likely disconnection from the theatrical world.

  20. Mineralogical characterization of historical portuguese wall tiles of Sao Luis, Maranhao, Brazil

    International Nuclear Information System (INIS)

    Rivas Mercury, J.M.; Vasconcelos, N.S.L.S.; Cabral, A.A.; Pereira, D.J. Costa; Angelica, R.S.

    2010-01-01

    Portuguese wall tiles from centuries, XVII, XVIII and XIX, found in Sao Luis Maranhao has been studied by X-ray diffraction, in order to interpret the possible raw material and burning temperature. The mineral phases, Quartz, Wollastonite, Calcite and Gehlenite were identified in all samples. Based on the results it is possible to affirm that the main raw materials used to manufacture this materials was probably mixtures of kaolinite clay and calcite. Based on the mineralogical information it was also possible to state that burning temperature of this wall tiles was lower than 1000 deg C. (author)

  1. A propósito de José Luis Brea: del archivo a la RAM

    Directory of Open Access Journals (Sweden)

    Fernando Broncano

    2014-06-01

    Full Text Available The philosopher José Luis Brea proposes a notion of memory spread around a network of connections, which reveals a conception of culture based on a RAM structure and contrary to the culture of archive. The underwent changes in the classification of disciplines caused by individual’s attitudes deriving from the new media hyperconnectivity environment will be reviewed here and the relevance in the present humanities of concepts such as exile, frontier and question without answer.

  2. Using directed information for influence discovery in interconnected dynamical systems

    Science.gov (United States)

    Rao, Arvind; Hero, Alfred O.; States, David J.; Engel, James Douglas

    2008-08-01

    Structure discovery in non-linear dynamical systems is an important and challenging problem that arises in various applications such as computational neuroscience, econometrics, and biological network discovery. Each of these systems have multiple interacting variables and the key problem is the inference of the underlying structure of the systems (which variables are connected to which others) based on the output observations (such as multiple time trajectories of the variables). Since such applications demand the inference of directed relationships among variables in these non-linear systems, current methods that have a linear assumption on structure or yield undirected variable dependencies are insufficient. Hence, in this work, we present a methodology for structure discovery using an information-theoretic metric called directed time information (DTI). Using both synthetic dynamical systems as well as true biological datasets (kidney development and T-cell data), we demonstrate the utility of DTI in such problems.

  3. Socratic Questioning-Guided Discovery

    Directory of Open Access Journals (Sweden)

    M. Hakan Türkçapar

    2012-04-01

    Full Text Available “Socratic Method” is a way of teaching philosophical thinking and knowledge by asking questions which was used by antique period greek philosopher Socrates. Socrates was teaching knowledge to his followers by asking questions and the conversation between them was named “Socratic Dialogues”. In this meaning, no novel knowledge is taught to the individual but only what is formerly known is reminded and rediscovered. The form of socratic questioning which is used during the process of cognitive behavioral therapy is known as Guided Discovery. In this method it is aimed to make the client notice the piece of knowledge which he could notice but is not aware with a series of questions. Socratic method or guided discovery consists of several steps which are: Identifying the problem by listening to the client and making reflections, finding alternatives by examining and evaluating, reidentification by using the newly found information and questioning the old distorted belief and reaching to a conclusion and applying it. Question types used during these procedures are, questions for gaining information, questions revealing the meanings, questions revealing the beliefs, questions about behaviours during the similar past experiences, analyse questions and analytic synthesis questions. In order to make the patient feel understood it is important to be empathetic and summarising the problem during the interview. In this text, steps of Socratic Questioning-Guided Discovery will be reviewed with sample dialogues after eachstep. [JCBPR 2012; 1(1.000: 15-20

  4. Emma Zunz by Jorge Luis Borges: the Concept of Justice

    Directory of Open Access Journals (Sweden)

    Rosa Vila

    2014-12-01

    Full Text Available Emma Zunz, by Jorge Luis Borges, is the story of a girl who decides to kill her boss in order to avenge her father’s death, believing that her father’s version of an event that occurred years before was true. Thus, she devises a secret plan, which includes losing her virginity to a complete stranger, shortly before committing the crime, so she could argue that her boss had raped her and that she killed him in self-defense. Firstly, the text shows the contrast between formal justice and taking justice into own hands. Secondly, the question of self-inflicted punishment, which in the story takes place before the perpetration of the crime. Finally, the issue whether truth is the version that can be inferred from the evidence presented in a trial, or the one which is kept to themselves by those involved in a crime. Emma Zunz, de Jorge Luis Borges, es la historia de una chica que decide matar a su jefe para vengar la muerte de su padre, creyendo que la versión de su padre de un hecho que ocurrió años atrás era cierta. De este modo, diseña un plan secreto, que incluye la pérdida de su virginidad con un desconocido, poco antes de cometer el crimen, para poder argumentar que su jefe la había violado y que ella lo mató en defensa propia. En primer lugar, el texto muestra el contraste entre la justicia formal y la justicia por cuenta propia. En segundo lugar, la cuestión de la pena infligida a uno mismo, lo que en la historia se produce antes de la comisión del delito. Por último, la cuestión de si la verdad es la versión que se puede inferir de las pruebas presentadas en un juicio, o la que se guardan para sí mismas las personas involucradas en un crimen. DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2519490

  5. Las políticas forestales en el estado de San Luis Potosí en el porfiriato

    Directory of Open Access Journals (Sweden)

    Julio César Errejón Gómez

    2017-04-01

    Full Text Available Las acciones y omisiones del presente en materia de política forestal pueden clarificarse si se revisan los antecedentes históricos. Por ello, el objetivo de esta investigación fue analizar la influencia del contexto internacional sobre las políticas forestales implementadas durante el régimen de Porfirio Díaz. Se amplía el panorama sobre las de uso y conservación de los bosques, así como sus repercusiones en San Luis Potosí. Para contextualizar los procesos mencionados, se realizó una consulta exhaustiva de documentos históricos y bibliográficos, y se encontró que el entorno internacional incentivó la creación de leyes e instituciones federales y locales para regular la explotación, el manejo y la conservación de los bosques. A pesar de ello, en esta entidad hubo una reducción importante en sus superficies boscosas; además, el gobierno federal y estatal no evidenció un interés por preservarlas. _______________ Current actions and omissions in forest policy can be clarified if the historical background is reviewed. Therefore, the objective of this research is to analyze the influence of the international context on forest policies implemented during the regime of Porfirio Diaz (1876-1911. In particular, it aims to broaden the outlook on government policies created for the management, use and conservation of forests and their impacts on San Luis Potosi. A thorough consultation of historical and bibliographical documents was made to understand the historical processes. It was found that the international environment encouraged the creation of laws, regulations and federal and local institutions for the purpose of regulating the exploitation, management and conservation of forests. However, the state of San Luis Potosi experienced a significant reduction in their forest areas; in addition, the federal and state governments showed no interest in applying conservation of forests in Potosi territory.

  6. NEUMOCISTOSIS EN EL SERVICIO DE MEDICINA INTERNA, COMPLEJO HOSPITALARIO UNIVERSITARIO “DR. LUIS RAZETTI”, BARCELONA, VENEZUELA, 2011-2012 I PNEUMOCYSTOSIS IN THE INTERNAL MEDICINE SERVICE, UNIVERSITY HOSPITAL COMPLEX “DR. LUIS RAZETTI”, BARCELONA, VENEZUELA, 2011-2012

    Directory of Open Access Journals (Sweden)

    Fadi Wahab-El-Fatairi

    2015-07-01

    Full Text Available In Venezuela and in the state Anzoátegui, the pneumocystosis, is little studied. To weigh that it is an infection opportunist caused by Pneumocystis jirovecii, it causes pneumonia of high morbility and mortality. The inmunocompromised patient is those that present bigger risks of acquiring this infection. The objectives of this investigation were to determine the infection frequency for P. jirovecii in patient with breathing symptoms and immunocompromised hospitalized in the Service of Internal Medicine of the Complex Hospital University “Dr. Luis Razetti", and to describe the clinical parameters, of laboratory, radiological and epidemic. To increase the sensibility of the diagnosis etiologic of the pneumocystosis you employment the combination of microscopic methods (Giemsa and direct immunofluorescence technique. 52 samples of spontaneous sputum were studied, which were processed by fluidification -concentration. Results: 8 patients (15.38% they were positive. The most frequent clinical manifestations among the patients with pneumocystosis were the dyspnea (75%, cough (62% and bullous (50% they were the most common signs among those infected, the one infiltrated alveolar (62.5% and the spill pleural (37.5% they prevailed as radiological signs. Was the LDH presented in values 300 UI/L in 5 of the positive patients. Other common discoveries were: moderate anemia and breathing alkalosis. The evaluated epidemic aspects were the gender, occupation, smoking, accumulation and comorbidities, in this last aspect, the diabetes, hypertension and infection for the VIH was opposing comorbidities among these patients. The confirmation of the infection in the state Anzoátegui, demonstrates that in this hospital the agent exists and probably you this underdiagnosticated the pneumocystosis.

  7. Diagnóstico etiológico de la ceguera de Jorge Luis Borges basado en su obra literaria

    Directory of Open Access Journals (Sweden)

    Mario Enrique de la Piedra Walter

    2017-07-01

    Conclusiones: Pese a que la miopía degenerativa es la etiología más probable de la ceguera de Jorge Luis Borges, no es posible descartar por completo otras oftalmopatías sin una exploración física adecuada. Se cumple el objetivo solo en el marco presuntivo.

  8. OS VINHOS DE MÚRCIA: CONTRIBUTO DE JOSÉ LUIS ANDRÉS SARASA

    Directory of Open Access Journals (Sweden)

    Victor Dordio

    2011-01-01

    Full Text Available José Luis Andrés Sarasa y su equipo de investigadores de la Universidad de Murcia hizo un excelente análisis estructural de la producción de vino en la Región de Murcia en el marco del proyecto «Filières Innovantes» (2002-2005. Los temas del espacio y tiempo, la tipología de los productores, bajo la óptica del savoir-faire, han sido minuciosamente estudiados y presentados. Nuestra contribución a este estudio consistió en un capítulo sobre el turismo del vino, que no se trató anteriormente debido a la falta de tiempo.

  9. Introduction to the Special Collection of Papers on the San Luis Basin Sustainability Metrics Project: A Methodology for Evaluating Regional Sustainability

    Science.gov (United States)

    This paper introduces a collection of four articles describing the San Luis Basin Sustainability Metrics Project. The Project developed a methodology for evaluating regional sustainability. This introduction provides the necessary background information for the project, descripti...

  10. Usability Study Identifies Vocabulary, Facets, and Education as Primary Primo Discovery System Interface Problems

    Directory of Open Access Journals (Sweden)

    Ruby Muriel Lavallee Warren

    2017-09-01

    efficiently. Again, all eight participants found an article on the requested subject in Test 1, Task 2, but two were unable to determine if the article met peer review requirements. One participant used the peer-reviewed journals facet, while the rest attempted to determine this using the item record or with facilitator help. All seven participants in Test 2 were able to locate the book requested in Task 1 via title search, but most had difficulty determining what steps to take to check that book out. Five participants completed Test 2, Task 2 (finding a newspaper article on a topic unassisted, one completed it with assistance, and one could not complete it at all. Five users did not notice the Newspaper Articles facet, and no participants noticed resource type icons without facilitator prompting. Conclusions – The researchers, while noting that there were few experienced researchers and a narrow scope of disciplines in their sample, concluded that there were a number of clear barriers to successful research in the Primo interface. Participants rarely used post-search facets, although they used pre-search filtering when possible, and ignored links and tabs within search results in favour of clicking on the material’s title. This led to users missing helpful tools and features. They conclude that a number of the usability problems with Primo’s interface are standard discovery systems usability problems, and express concern that this has been inadequately addressed by vendors. They also note that a number of usability issues stemmed from misunderstandings of terminology, such as “peer-reviewed” or “citation”. They conclude that while they have been able to make several improvements to their Primo interface, such as adding an author limiter and changing “Peer-reviewed Journals” to “Peer-reviewed Articles”, further education of users will be the only way to solve many of these usability problems.

  11. Hydrogeologic Assessment of the East Bear Creek Unit, San LuisNational Wildlife Refuge

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, Nigel W.T.

    2007-07-15

    San Luis National Wildlife Refuge Complex to meetReclamation s obligations for Level 4 water supply under the CentralValley Project Improvement Act. Hydrogeological assessment of the EastBear Creek Unit of the San Luis National Wildlife Refuge was conductedusing a combination of field investigations and a survey of availableliterature from past US Geological Survey Reports and reports by localgeological consultants. Conservative safe yield estimates made using theavailable data show that the East Bear Creek Unit may have sufficientgroundwater resources in the shallow groundwater aquifer to meet aboutbetween 25 percent and 52 percent of its current Level II and between 17percent and 35 percent of its level IV water supply needs. The rate ofsurface and lateral recharge to the Unit and the design of the well fieldand the layout and capacity of pumped wells will decide both thepercentage of annual needs that the shallow aquifer can supply andwhether this yield is sustainable without affecting long-term aquiferquality. In order to further investigate the merits of pumping the nearsurface aquifer, which appears to have reasonable water quality for usewithin the East Bear Creek Unit -- monitoring of the potential sources ofaquifer recharge and the installation of a pilot shallow well would bewarranted. Simple monitoring stations could be installed both upstreamand downstream of both the San Joaquin River and Bear Creek and beinstrumented to measureriver stage, flow and electrical conductivity.Ideally this would be done in conjunction with a shallow pilot well,pumped to supply a portion of the Unit's needs for the wetland inundationperiod.

  12. El basamento de la sierra de San Luis: Nuevas evidencias magnéticas y sus implicancias tectónicas The basement of Sierra de San Luis: New magnetic evidence and tectonic implication

    OpenAIRE

    CJ Chernicoff; VA Ramos

    2003-01-01

    Los mapas aeromagnéticos disponibles de las sierras de San Luis y Comechingones en el sector sudoriental de las Sierras Pampeanas de Argentina, permiten examinar las características geológicas y estructurales de las unidades metamórficas e intrusivas del basamento de la región. A través de la aplicación del filtro de continuación ascendente a los datos del campo magnético total reducido al polo, se ha podido observar la configuración profunda de las distintas unidades. Entre ellas se destaca ...

  13. Recent advances in combinatorial biosynthesis for drug discovery

    Directory of Open Access Journals (Sweden)

    Sun H

    2015-02-01

    Full Text Available Huihua Sun,1,* Zihe Liu,1,* Huimin Zhao,1,2 Ee Lui Ang1 1Metabolic Engineering Research Laboratory, Institute of Chemical and Engineering Sciences, Agency for Science, Technology and Research, Singapore; 2Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, IL, USA *These authors contributed equally to this work Abstract: Because of extraordinary structural diversity and broad biological activities, natural products have played a significant role in drug discovery. These therapeutically important secondary metabolites are assembled and modified by dedicated biosynthetic pathways in their host living organisms. Traditionally, chemists have attempted to synthesize natural product analogs that are important sources of new drugs. However, the extraordinary structural complexity of natural products sometimes makes it challenging for traditional chemical synthesis, which usually involves multiple steps, harsh conditions, toxic organic solvents, and byproduct wastes. In contrast, combinatorial biosynthesis exploits substrate promiscuity and employs engineered enzymes and pathways to produce novel “unnatural” natural products, substantially expanding the structural diversity of natural products with potential pharmaceutical value. Thus, combinatorial biosynthesis provides an environmentally friendly way to produce natural product analogs. Efficient expression of the combinatorial biosynthetic pathway in genetically tractable heterologous hosts can increase the titer of the compound, eventually resulting in less expensive drugs. In this review, we will discuss three major strategies for combinatorial biosynthesis: 1 precursor-directed biosynthesis; 2 enzyme-level modification, which includes swapping of the entire domains, modules and subunits, site-specific mutagenesis, and directed evolution; 3 pathway-level recombination. Recent examples of combinatorial biosynthesis employing these

  14. 76 FR 414 - Tier 1 Environmental Impact Statement for the Los Angeles to San Luis Obispo (LOSSAN North) Rail...

    Science.gov (United States)

    2011-01-04

    ... expected growth in population and resulting increases in intercity travel demand between Los Angeles and San Luis Obispo. As a result of this growth in travel demand, their travel delays from the growing... environmental analysis to help make corridor level decisions regarding the level of intercity passenger rail...

  15. Real-Time Water Quality Monitoring and Habitat Assessment in the San Luis National Wildlife Refuge

    OpenAIRE

    Quinn, Nigel W.T.; Hanlon, Jeremy S.; Burns, Josephine R.; Stromayer, Karl A.K.; Jordan, Brandon M.; Ennis, Mike J.; Woolington, Dennis W.

    2005-01-01

    The project report describes a two year experiment to control wetland drainage to the San Joaquin River of California from the San Luis National Wildlife Refuge using a decision support system for real-time water quality management. This system required the installation and operation of one inlet and three drainage flow and water quality monitoring stations which allowed a simnple mass balance model to be developed of the seasonally managed wetlands in the study area. Remote sensing meth...

  16. Problem-based Learning and Problem Finding Among University Graduate Students

    OpenAIRE

    Ankit, A, Ravankar; Shotaro, Imai; Michiyo, Shimamura; Go, Chiba; Taichi, Takasuka

    2017-01-01

    In recent years, problem-based learning (PBL) techniques have been gaining momentum in schools and university curricula around the world. The main advantage of the PBL method is that it promotes creative problem solving, improves cognition and enhances overall thought processes in learners. For most PBL-style programmes, problem solving is at the core, although the notion of problem discovery or problem finding is not seriously considered. In most cases, students are always presen...

  17. Disseminating Evidence-Based Physical Education Practices in Rural Schools: The San Luis Valley Physical Education Academy.

    Science.gov (United States)

    Belansky, Elaine S; Cutforth, Nick; Kern, Ben; Scarbro, Sharon

    2016-09-01

    To address childhood obesity, strategies are needed to maximize physical activity during the school day. The San Luis Valley Physical Education Academy was a public health intervention designed to increase the quality of physical education and quantity of moderate to vigorous physical activity (MVPA) during physical education class. Elementary school physical education teachers from 17 schools participated in the intervention. They received SPARK curriculum and equipment, workshops, and site coordinator support for 2 years. A pre/post/post within physical education teacher design was used to measure intervention effectiveness. System for Observing Fitness Instruction Time (SOFIT) and a physical education teacher survey were collected 3 times. MVPA increased from 51.1% to 67.3% over the 2-year intervention resulting in approximately 14.6 additional hours of physical activity over a school year and 4662 kcal or 1.33 lbs. of weight gain prevention. More time was spent on skill drills and less time on classroom management and free play. The San Luis Valley Physical Education Academy succeeded in increasing rural, low-income students' physical activity. The multicomponent intervention contributed to the program's success. However, cost-effective approaches are needed to disseminate and implement evidencebased practices aimed at increasing students' physical activity during the school day.

  18. TECNOLOGÍA LÍTICA Y USO DIFERENCIAL DEL ESPACIO EN ESTANCIA LA SUIZA, SAN LUIS, ARGENTINA / Lithic technology and differential use of space in Estancia La Suiza, San Luis, Argentina

    Directory of Open Access Journals (Sweden)

    Gisela Sario

    2013-07-01

    Full Text Available El trabajo pretende contribuir, desde la perspectiva de la organización de la tecnología, al conocimiento de las ocupaciones cazadoras-recolectoras que habitaron las inmediaciones de la Sierra de la Estanzuela, en la provincia de San Luis, Argentina. Se explican cómo fueron las secuencias de producción de herramientas en los sitios de la localidad arqueológica Estancia La Suiza, a partir del análisis de los materiales líticos recuperados en excavación y prospecciones sistemáticas. Las metodologías propuestas para abordar este estudio corresponden al análisis nodular y más específicamente a una combinación del análisis tipológico y no tipológico. Los resultados permiten interpretar que en esta localidad hubo un uso diferencial del espacio, particularmente en dos sitios que son Estancia La Suiza 2 y Estancia La Suiza 3. Abstract This paper aims at gaining insight, from the angle of technological organization, into the hunter-gatherer communities that dwelled in the surrounding areas of Sierras de la Estanzuela, in the province of San Luis, Argentina. The sequence of tool development in the archaeological site of Estancia La Suiza is described from analysis of lithic materials from excavation and systematic surveys. The methods adopted for conducting this study form part of Minimal Nodule analysis (MANA and more specifically a combination of typological and non-typological analysis. Results indicate that this site evidences a differential use of space, more specifically found in Estancia La Suiza 2 and Estancia La Suiza 3. 

  19. Literature-related discovery techniques applied to ocular disease : a vitreous restoration example

    NARCIS (Netherlands)

    Kostoff, Ronald N.; Los, Leonoor I.

    2013-01-01

    Purpose of reviewLiterature-related discovery and innovation (LRDI) is a text mining approach for bridging unconnected disciplines to hypothesize radical discovery. Application to medical problems involves identifying key disease symptoms, and identifying causes and treatments for those symptoms

  20. Alvarez, Luis Walter (1911-88)

    Science.gov (United States)

    Murdin, P.

    2000-11-01

    Physicist and astronomer, born in San Francisco, CA, professor at the University of California, Nobel prizewinner (1968) for his discoveries in particle physics. Used cosmic rays to `x-ray' the pyramids of Egypt, finding in particular that the tombs in the Great Pyramid at Giza had no hidden rooms. Alvarez (and his son) discovered globally distributed iridium at the Cretaceous/Tertiary boundary i...

  1. PARADOXURILE CONCEPŢIEI POLITICE ÎN OPERA LUI JEAN-JACQUES ROUSSEAU

    Directory of Open Access Journals (Sweden)

    Alexandru MAZILU

    2015-12-01

    Full Text Available Ideile lui Rousseau au avut un impact major asupra societăţii la sfârşitul sec. al XVIII-lea şi pe parcursul întregii perioade a sec. al XIX-lea. Aceste idei au imprimat un suflu modern cugetului său, fiind considerat şi un ideologist politic, o voce puternică a Revoluţiei Franceze şi un pioner al curentului romantic. În legătură cu domeniul nostru de studiu, paradoxurile concepţiei politice ale lui Rousseau se referă la contradicţia dintre aspiraţiile modernităţii şi criticile violente ale progresului social. El pune accentul pe contradicţia dintre încrede-rea deplină în ,,contractul social”, ca pattern cultural şi lipsa de încredere în ,,educaţia socială”. Unicul mod de a depăşi aceste contradicţii este abordarea noului model al filosofiei educaţiei bazat pe reforme radicale pentru a facilita autodezvoltarea individului.   THE PARADOXES OF POLITICAL CONCEPTION IN THE WORK OF JEAN-JACQUES ROUSSEAUHis ideas have a big impact on the society at the end of the 18th century and the whole 19th century period. These ideas transform his spirit into a modern one, as well as a political ideologist, main voice of the French Revolution and pioneer of the Romantic Movement. Related to our article subject, Rousseau's political conceptual paradoxes refer to the contradiction between moderni-ty aspiration and the violent critic of the social progress. He emphasizes the contradiction between full trust of the "social contract", as a cultural pattern and the distrust of the "social education." The only way to leave the contradictions behind is his new education philosophy pattern based on a radical reform in order for the individual to develop himself.

  2. METROPOLlZAÇÃO NA ILHA OE SÃO LUIS E SEUS IMPACTOS SANITÁRIOS E AMBIENTAIS

    Directory of Open Access Journals (Sweden)

    Lúcio Antônio Alves de Macêdo

    2012-01-01

    Full Text Available The paper presents aspects 01 the Environmental Sanitation considered on the island 01 Maranhão, lrom a historical perspective, restoring the role 01 sanitation in improving the quality 01 lile and highlighting the low leveis 01 coverage 01 water supply (56% and sanitation (12%, and the precariousness 01 the disposal 01 solid waste in the municipalities 01 São Luis, Paço do Lumiar, Raposa and São José de Ribamar. ln particular there is no more available land lar construction 01 landlills, because 01 environmental implications in areas 01 watershed protection. As a result 01 the studies showed that water pollution in major rivers 01 the island with the pollution load 0160 ton / day, committing the multiple uses 01 the river Anil, Bacanga, Patience and Tibiri, as well as high rates 01 inlectious diseases and child mortality the precariousness 01 Sanitation problems associated with the generation 01 700 t / d 01 waste. ln conclusion the study shows the need lar the implementation 01 environmental planning, ordering the use 01 space and adopting techniques 01 control and environmental health lar the population.

  3. Queen's discovery lauded by top scientific journal

    CERN Multimedia

    McGrady, S

    2002-01-01

    A scientific breakthrough at Queen's University's Sudbury Neutrino Observatory has received major international recognition. The journal Science ranked the discovery that cracked the "neutrino problem" second, in the journal's top 10 scientific achievements of 2002 (1/2 page).

  4. Human papillomavirus type 16 variants in cervical intraepithelial neoplasia and invasive carcinoma in San Luis Potosí City, Mexico

    Science.gov (United States)

    López-Revilla, Rubén; Pineda, Marco A; Ortiz-Valdez, Julio; Sánchez-Garza, Mireya; Riego, Lina

    2009-01-01

    Background In San Luis Potosí City cervical infection by human papillomavirus type 16 (HPV16) associated to dysplastic lesions is more prevalent in younger women. In this work HPV16 subtypes and variants associated to low-grade intraepithelial lesions (LSIL), high-grade intraepithelial lesions (HSIL) and invasive cervical cancer (ICC) of 38 women residing in San Luis Potosí City were identified by comparing their E6 open reading frame sequences. Results Three European (E) variants (E-P, n = 27; E-T350G, n = 7; E-C188G, n = 2) and one AA-a variant (n = 2) were identified among the 38 HPV16 sequences analyzed. E-P variant sequences contained 23 single nucleotide changes, two of which (A334G, A404T) had not been described before and allowed the phylogenetic separation from the other variants. E-P A334G sequences were the most prevalent (22 cases, 57.9%), followed by the E-P Ref prototype (8 cases, 21.1%) and E-P A404T (1 case, 2.6%) sequences. The HSIL + ICC fraction was 0.21 for the E-P A334G variants and 0.00 for the E-P Ref variants. Conclusion We conclude that in the women included in this study the HPV16 E subtype is 19 times more frequent than the AA subtype; that the circulating E variants are E-P (71.1%) > E-T350G (18.4%) > E-C188G (5.3%); that 71.0% of the E-P sequences carry the A334G single nucleotide change and appear to correspond to a HPV16 variant characteristic of San Luis Potosi City more oncogenic than the E-P Ref prototype. PMID:19216802

  5. Discovery and development of new antibacterial drugs: learning from experience?

    Science.gov (United States)

    Jackson, Nicole; Czaplewski, Lloyd; Piddock, Laura J V

    2018-06-01

    Antibiotic (antibacterial) resistance is a serious global problem and the need for new treatments is urgent. The current antibiotic discovery model is not delivering new agents at a rate that is sufficient to combat present levels of antibiotic resistance. This has led to fears of the arrival of a 'post-antibiotic era'. Scientific difficulties, an unfavourable regulatory climate, multiple company mergers and the low financial returns associated with antibiotic drug development have led to the withdrawal of many pharmaceutical companies from the field. The regulatory climate has now begun to improve, but major scientific hurdles still impede the discovery and development of novel antibacterial agents. To facilitate discovery activities there must be increased understanding of the scientific problems experienced by pharmaceutical companies. This must be coupled with addressing the current antibiotic resistance crisis so that compounds and ultimately drugs are delivered to treat the most urgent clinical challenges. By understanding the causes of the failures and successes of the pharmaceutical industry's research history, duplication of discovery programmes will be reduced, increasing the productivity of the antibiotic drug discovery pipeline by academia and small companies. The most important scientific issues to address are getting molecules into the Gram-negative bacterial cell and avoiding their efflux. Hence screening programmes should focus their efforts on whole bacterial cells rather than cell-free systems. Despite falling out of favour with pharmaceutical companies, natural product research still holds promise for providing new molecules as a basis for discovery.

  6. Observations on nests of Crocodylus moreletii in San Luis Potosí, Mexico Observaciones sobre nidos de Crocodylus moreletii en San Luis Potosí, México

    Directory of Open Access Journals (Sweden)

    Armando H. Escobedo-Galván

    2011-03-01

    Full Text Available Nesting ecology of Morelet's crocodile (Crocodylus moreletii has been documented since 1940. However, only 2 nests constructed on floating vegetation have been recorded. Here, we presented additional information from a mainland population of C. moreletii in the Ciénega de Cabezas wetland, San Luis Potosí, describing 2 nests constructed on floating mats of cattails. The nests were constructed using Typha sp., close to the main channel. One nest was lost due to flooding, and contained 32 eggs. Seven eggs had a mean 72.6 ± 2.63 mm length (range = 70.0 -75.0 mm, 45.0 ± 2.30 mm width (range = 41.0-48.0 mm, and 140.7 ± 2.98 mm diameter (range = 136.0-145.0 mm. We suggest that the use of floating vegetation for nesting by C. moreletii is related to the availability of aquatic vegetation, combined with the lack of adequate nesting sites on land.La ecología de anidación del cocodrilo de pantano (Crocodylus moreletii ha sido documentada desde 1940. Sin embargo, sólo existen 2 registros de nidos construidos sobre vegetación acuática. Presentamos información adicional de 2 nidos (N1 y N2 construidos en este tipo de hábitat en una población ubicada en la Ciénega de Cabezas en el estado de San Luis Potosí. Los nidos fueron construidos sobre Typha sp., cerca del cauce principal de la ciénega. El N2 se perdió por inundación, en su interior encontramos 32 huevos, los promedios (± SD del largo, ancho y diámetro de 7 huevos fueron 72.6 ± 2.63 mm (rango = 70.0 -75.0 mm, 45.0 ± 2.30 mm (rango = 41.0-48.0 mm, 140.7 ± 2.98 mm (rango = 136.0-145.0 mm, respectivamente. Sugerimos que este tipo de sitios para anidar por parte de C. moreletii está relacionado con la disponibilidad de vegetación acuática, combinado con la ausencia de sitios adecuados en tierra firme.

  7. Missionary Pragmalinguistics: Father Diego Luis de Sanvitores’ grammar (1668) within the tradition of Philippine grammars

    OpenAIRE

    Winkler, A.P.

    2016-01-01

    The grammar written in Latin, in 1668, by the Jesuit missionary Father Diego Luis de Sanvitores (1627-1672) is the oldest description we have of Chamorro, a language spoken on the Mariana islands. The grammar received a number of bad reviews and as a consequence has become neglected and almost forgotten. The main point of criticism has been that Sanvitores used the Latin grammatical framework to explain a language that in many ways does not fit this framework. In this thesis it is argued inst...

  8. On editing the fifth stanza of El aire se serena by fray Luis

    Directory of Open Access Journals (Sweden)

    Aquilino Suárez Pallasá

    2011-12-01

    Full Text Available Although many scholars and editors of the ode «El aire se serena» by fray Luis de León have denied or questioned the authenticity of its fifth stanza, there now seems to be a general assent to its acceptance. The reason for such a change of heart has not to do with textual criticism proper, but with literature. The sources of the ode are said to justify it. In this paper a strictly critico-textual demonstration of the authenticity of stanza 5 is proposed, placing emphasis on the cause of the diffraction displayed in the erroneous lectiones of a segment of the stanza.

  9. Distribution and abundance of Least Bell’s Vireos (Vireo bellii pusillus) and Southwestern Willow Flycatchers (Empidonax traillii extimus) on the Middle San Luis Rey River, San Diego County, southern California—2017 data summary

    Science.gov (United States)

    Allen, Lisa D.; Howell, Scarlett L.; Kus, Barbara E.

    2018-04-20

    We surveyed for Least Bell’s Vireos (LBVI) (Vireo bellii pusillus) and Southwestern Willow Flycatchers (SWFL) (Empidonax traillii extimus) along the San Luis Rey River, between College Boulevard in Oceanside and Interstate 15 in Fallbrook, California (middle San Luis Rey River), in 2017. Surveys were conducted from April 13 to July 11 (LBVI) and from May 16 to July 28 (SWFL). We found 146 LBVI territories, at least 107 of which were occupied by pairs. Five additional transient LBVIs were detected. LBVIs used five different habitat types in the survey area: mixed willow, willow-cottonwood, willow-sycamore, riparian scrub, and upland scrub. Forty-four percent of the LBVIs occurred in habitat characterized as mixed willow and 89 percent of the LBVI territories occurred in areas with greater than 50 percent native plant cover. Of 16 banded LBVIs detected in the survey area, 8 had been given full color-band combinations prior to 2017. Four other LBVIs with single (natal) federal bands were recaptured and banded in 2017. Three LBVIs with single dark blue federal bands indicating that they were banded as nestlings on the lower San Luis Rey River and one LBVI with a single gold federal band indicating that it was banded as a nestling on Marine Corps Base Camp Pendleton (MCBCP) could not be recaptured for identification. One banded LBVI emigrated from the middle San Luis Rey River to the lower San Luis Rey River in 2017.One resident SWFL territory and one transient Willow Flycatcher of unknown subspecies (WIFL) were observed in the survey area in 2017. The resident SWFL territory, which was comprised of mixed willow habitat (5–50 percent native plant cover), was occupied by a single male from May 22 to June 21, 2017. No evidence of pairing or nesting activity was observed. The SWFL male was banded with a full color-combination indicating that he was originally banded as a nestling on the middle San Luis Rey River in 2014 and successfully bred in the survey area in 2016

  10. Pattern Discovery in Time-Ordered Data; TOPICAL

    International Nuclear Information System (INIS)

    CONRAD, GREGORY N.; BRITANIK, JOHN M.; DELAND, SHARON M.; JENKIN, CHRISTINA L.

    2002-01-01

    This report describes the results of a Laboratory-Directed Research and Development project on techniques for pattern discovery in discrete event time series data. In this project, we explored two different aspects of the pattern matching/discovery problem. The first aspect studied was the use of Dynamic Time Warping for pattern matching in continuous data. In essence, DTW is a technique for aligning time series along the time axis to optimize the similarity measure. The second aspect studied was techniques for discovering patterns in discrete event data. We developed a pattern discovery tool based on adaptations of the A-priori and GSP (Generalized Sequential Pattern mining) algorithms. We then used the tool on three different application areas-unattended monitoring system data from a storage magazine, computer network intrusion detection, and analysis of robot training data

  11. El modelo ideal de interactividad es la conversación. Entrevista a José Luis Orihuela

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    Juan Salvador Victoria Mas

    2012-04-01

    Full Text Available José Luis Orihuela, "profesor universitario, conferenciante y bloguer" - tal y como él mismo se define-, habla sobre la interactividad como una potencia o una capacidad de los dispositivos (ordenadores y redes que actualiza o ejecuta el usuario en la medida en que inicia acciones que generan una respuesta por parte del sistema o de otros usuarios. Tras unas preguntas para adentrarnos en dicho concepto, Orihuela relaciona interactividad con diálogo y otros conceptos.

  12. A New Destination for "The Flying Bus"?: The Implications of Orlando-Rican Migration for Luis Rafael Sanchez's "La guagua aerea"

    Science.gov (United States)

    Barreneche, Gabriel Ignacio; Lombardi, Jane; Ramos-Flores, Hector

    2012-01-01

    Puerto Rican author Luis Rafael Sanchez's "La guagua aerea" explores the duality, hybridity, and fluidity of US-Puerto Rican identity through the frequent travel of migrants between New York City (the traditional destination city for Puerto Rican migrants) and the island. In recent years, however, the "flying bus" has adopted a…

  13. Luis Fayad. Dalla narrativa urbana agli innesti socioculturali. Presentazione

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    Martha L. Canfield

    2013-03-01

    Full Text Available The article looks at Luis Fayad’s novel La caída de los puntos cardinales (2000 in order to foreground the influence of Arabic on the Colom- bian author whose grandparents were Lebanese. Born in Bogotá in 1945, Fayad published the novel after being identified as one of the first Colombian novelists dealing with urban literature. It represents a change of direction in his career, as Fayad narrates the entire life of six main characters, four men and two women, who decide to leave Lebanon and migrate to South America, ending up in Colombia. The analysis will focus on the importance of the circulation of the book in Italy by virtue of issues of intercultural exchange embedded in the novel. La caída de los puntos cardinales mixes Arabic tradition and Colombian customs; in the novel, Fayad achieves a cross-cultural story that may provide a successful model of integration. The Spanish-Italian translation and a critical approach to the language used by the novelist and employed by the translator will complete the essay.

  14. Survey of the University "Luis Vargas Torres" through Econometric Techniques. Comprehensive Income

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    Ramón Rodríguez-Betancourt

    2015-12-01

    Full Text Available Government Programme 2013-2017 defines in higher education, the principles of the curriculum proposals of much public interest careers. In this regard the authorities of the Technical University "Luis Vargas Torres" of Esmeraldas, have taken the decision to evaluate its management and action against the development of the province and the country. Therefore, the objective of this research is the application of a survey of students of different specialties, Faculty of Engineering and Technology to explore their views on the educational process, research, outreach, culture and sport, stratified random sampling with results showing that key processes are completed by 66% on average is applied, indicating that the authority still has to set goals to overcome the short comings that have an emphasis on research.

  15. Superinfection between Influenza and RSV Alternating Patterns in San Luis Potosí State, México

    Science.gov (United States)

    Velasco-Hernández, Jorge Xicoténcatl; Núñez-López, Mayra; Comas-García, Andreu; Cherpitel, Daniel Ernesto Noyola; Ocampo, Marcos Capistrán

    2015-01-01

    The objective of this paper is to explain through the ecological hypothesis superinfection and competitive interaction between two viral populations and niche (host) availability, the alternating patterns of Respiratory Syncytial Virus (RSV) and influenza observed in a regional hospital in San Luis Potosí State, México using a mathematical model as a methodological tool. The data analyzed consists of community-based and hospital-based Acute Respiratory Infections (ARI) consultations provided by health-care institutions reported to the State Health Service Epidemiology Department from 2003 through 2009. PMID:25803450

  16. Infección congénita por citomegalovirus en recién nacidos del estado de San Luis Potosí, México Congenital cytomegalovirus infection in newborn infants from the state of San Luis Potosí, Mexico

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    Daniel E Noyola

    2011-12-01

    Full Text Available OBJETIVO: Determinar la prevalencia de infección congénita por citomegalovirus en recién nacidos participantes en el programa de tamiz neonatal de los Servicios de Salud de San Luis Potosí. MATERIAL Y MÉTODOS: Se evaluó la presencia de citomegalovirus en muestras de sangre almacenadas en papel filtro. RESULTADOS. Se detectó la presencia de citomegalovirus en 10 (0.68% de 1 457 muestras estudiadas. No se encontraron diferencias en las características de los recién nacidos con infección congénita en comparación con aquéllos sin infección. CONCLUSIONES: Es necesario concientizar a los profesionales de la salud sobre la prevalencia e impacto de la infección congénita por citomegalovirus.OBJECTIVE: To determine the prevalence of congenital cytomegalovirus infection in newborn infants included in the neonatal screening program coordinated by the State Health Services in San Luis Potosí. MATERIAL AND METHODS: We evaluated the presence of cytomegalovirus in blood samples stored in filter paper. RESULTS: Cytomegalovirus was detected in 10 (0.68% of the 1 457 samples included in the study. There were no differences in the characteristics of infants with congenital infection compared to those without infection. CONCLUSIONS: It is necessary to increase awareness of health professionals regarding the prevalence and impact of congenital cytomegalovirus infection.

  17. Discovery and preclinical development of new antibiotics.

    Science.gov (United States)

    Hughes, Diarmaid; Karlén, Anders

    2014-05-01

    Antibiotics are the medical wonder of our age, but an increasing frequency of resistance among key pathogens is rendering them less effective. If this trend continues the consequences for cancer patients, organ transplant patients, and indeed the general community could be disastrous. The problem is complex, involving abuse and overuse of antibiotics (selecting for an increasing frequency of resistant bacteria), together with a lack of investment in discovery and development (resulting in an almost dry drug development pipeline). Remedial approaches to the problem should include taking measures to reduce the selective pressures for resistance development, and taking measures to incentivize renewed investment in antibiotic discovery and development. Bringing new antibiotics to the clinic is critical because this is currently the only realistic therapy that can ensure the level of infection control required for many medical procedures. Here we outline the complex process involved in taking a potential novel antibiotic from the initial discovery of a hit molecule, through lead and candidate drug development, up to its entry into phase I clinical trials. The stringent criteria that a successful drug must meet, balancing high efficacy in vivo against a broad spectrum of pathogens, with minimal liabilities against human targets, explain why even with sufficient investment this process is prone to a high failure rate. This emphasizes the need to create a well-funded antibiotic discovery and development pipeline that can sustain the continuous delivery of novel candidate drugs into clinical trials, to ensure the maintenance of the advanced medical procedures we currently take for granted.

  18. "Non qua servus est, sed qua homo." Der rechtliche Status von Sklaven bei Luis de Molina

    OpenAIRE

    Simmermacher, Danaë

    2014-01-01

    Luis de Molina (1535-1600) grants slaves a legal status through which they can take up a position with respect to their masters between equivalent legal entity and legal object. Here, what is decisive is the figure of the subjective right, which both for Molina and modern proponents of this legal concept describes the 'right per se'. According to Molina's definition of ius, the denial of a subjective right or the hindrance of exercising an individual right represents an injustice. The rights ...

  19. Brote de encefalitis de San Luis en el Área Metropolitana Buenos Aires Outbreack of St. Luis encephalitis in the Metropolitan Buenos Aires Area

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    Alfredo Seijo

    2011-06-01

    Full Text Available Se describen los hallazgos epidemiológicos y clínicos de 13 enfermos con diagnóstico de infección por virus de la encefalitis de San Luis, con transmisión entre enero y marzo de 2010, en el Area Metropolitana Buenos Aires (AMBA. Los 13 enfermos, promedio de edad 38 años, tuvieron un comienzo agudo caracterizado por hipertermia y cefalea. Entre los días dos y diez de iniciados los síntomas, 7/13 enfermos tuvieron signos y síntomas de compromiso neurológico caracterizado por meningitis sin signos encefálicos en 1/7. En 6/7 los hallazgos más frecuentes fueron: rigidez de nuca, desorientación temporoespacial, fotofobia, confusión y alteración del lenguaje. Dos resonancias magnéticas y un electroencefalograma presentaron signos de afectación de lóbulos temporales. El líquido cefalorraquídeo se caracterizó por pleocitosis con predominio de células mononucleadas, glucorraquia normal y discreto aumento de proteínas. No hubo casos fatales. En 6/13 pacientes la sospecha clínica inicial fue dengue. Por la agrupación espacial y temporal de los casos puede considerarse un brote epidémico, el primero conocido en el AMBA, ya que no se había notificado previamente la circulación epidémica del virus.We describe the epidemiological and clinical findings of 13 patients with diagnosis of infection by St. Louis encephalitis virus, transmitted between January and March 2010 in Buenos Aires Metropolitan Area (AMBA. Thirteen patients, average age 38 years, had an acute onset with hyperthermia and headache. Between days two and ten of the onset of symptoms, 7/13 patients had signs and symptoms of neurological involvement. This was characterized by meningitis without encephalic sings in 1/7 and in 6/7 the most frequent findings were: stiff neck, disorientation, photophobia, confusion and language impairment. Two MR and one EEG revealed signs of involvement of temporal lobes. The cerebrospinal fluid showed pleocytosis with predominance of

  20. Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery

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    Nicholas Ekow Thomford

    2018-05-01

    Full Text Available The therapeutic properties of plants have been recognised since time immemorial. Many pathological conditions have been treated using plant-derived medicines. These medicines are used as concoctions or concentrated plant extracts without isolation of active compounds. Modern medicine however, requires the isolation and purification of one or two active compounds. There are however a lot of global health challenges with diseases such as cancer, degenerative diseases, HIV/AIDS and diabetes, of which modern medicine is struggling to provide cures. Many times the isolation of “active compound” has made the compound ineffective. Drug discovery is a multidimensional problem requiring several parameters of both natural and synthetic compounds such as safety, pharmacokinetics and efficacy to be evaluated during drug candidate selection. The advent of latest technologies that enhance drug design hypotheses such as Artificial Intelligence, the use of ‘organ-on chip’ and microfluidics technologies, means that automation has become part of drug discovery. This has resulted in increased speed in drug discovery and evaluation of the safety, pharmacokinetics and efficacy of candidate compounds whilst allowing novel ways of drug design and synthesis based on natural compounds. Recent advances in analytical and computational techniques have opened new avenues to process complex natural products and to use their structures to derive new and innovative drugs. Indeed, we are in the era of computational molecular design, as applied to natural products. Predictive computational softwares have contributed to the discovery of molecular targets of natural products and their derivatives. In future the use of quantum computing, computational softwares and databases in modelling molecular interactions and predicting features and parameters needed for drug development, such as pharmacokinetic and pharmacodynamics, will result in few false positive leads in drug

  1. Natural Products for Drug Discovery in the 21st Century: Innovations for Novel Drug Discovery.

    Science.gov (United States)

    Thomford, Nicholas Ekow; Senthebane, Dimakatso Alice; Rowe, Arielle; Munro, Daniella; Seele, Palesa; Maroyi, Alfred; Dzobo, Kevin

    2018-05-25

    The therapeutic properties of plants have been recognised since time immemorial. Many pathological conditions have been treated using plant-derived medicines. These medicines are used as concoctions or concentrated plant extracts without isolation of active compounds. Modern medicine however, requires the isolation and purification of one or two active compounds. There are however a lot of global health challenges with diseases such as cancer, degenerative diseases, HIV/AIDS and diabetes, of which modern medicine is struggling to provide cures. Many times the isolation of "active compound" has made the compound ineffective. Drug discovery is a multidimensional problem requiring several parameters of both natural and synthetic compounds such as safety, pharmacokinetics and efficacy to be evaluated during drug candidate selection. The advent of latest technologies that enhance drug design hypotheses such as Artificial Intelligence, the use of 'organ-on chip' and microfluidics technologies, means that automation has become part of drug discovery. This has resulted in increased speed in drug discovery and evaluation of the safety, pharmacokinetics and efficacy of candidate compounds whilst allowing novel ways of drug design and synthesis based on natural compounds. Recent advances in analytical and computational techniques have opened new avenues to process complex natural products and to use their structures to derive new and innovative drugs. Indeed, we are in the era of computational molecular design, as applied to natural products. Predictive computational softwares have contributed to the discovery of molecular targets of natural products and their derivatives. In future the use of quantum computing, computational softwares and databases in modelling molecular interactions and predicting features and parameters needed for drug development, such as pharmacokinetic and pharmacodynamics, will result in few false positive leads in drug development. This review

  2. Engaging Students in Designing Movement: The Divergent Discovery Style of Teaching

    Science.gov (United States)

    Chatoupis, Constantine

    2018-01-01

    In the divergent discovery style of teaching the teacher designs problems that engage students in finding multiple solutions. The purpose of this article is to show how physical educators can use the divergent discovery style in the gymnasium. A brief description of this style and its connection to the SHAPE America National Standards for K-12…

  3. Abastecimento futuro da água potável abate, análise espacial e da vulnerabilidade da cidade de san luis potosi, méxico

    OpenAIRE

    Contreras Servín, Carlos; Galindo Mendoza, María Guadalupe

    2009-01-01

    O presente artigo discute e apresenta as condições físicas, sociais e económicas que afectam a imagem global e os problemas actuais respeito ao abastecimento de água potável da região metropolitana de San Luis Potosi. Entre os temas a abordar está a relação entre disponibilidade hídrica e aumento da população, bem como a evolução de extração de águas subterrâneas. Além disso, a pesquisa mostra um diagnóstico da situação actual de abastecimento de água potável em San Luis Potosi e áreas circun...

  4. Ampliación de la distribución de Teius oculatus y T. suquiensis (Sauria: Teiidae en la provincia de San Luis (República Argentina

    Directory of Open Access Journals (Sweden)

    Guerreiro, Analía C.

    1998-01-01

    Full Text Available Teius oculatus (D'Orbigny & Bibron, 1837. Dpto. La Capital. Localidades: Daniel Donovan (33°21'S; 66°15'W UNSUCH 0098; Ciudad de San Luis (33°18'S; 66°22'W UNSL-CH 0132, 0137. Teius suquiensis Avila & Martori, 1991. Dpto. La Capital. Localidades: Daniel Dono- van, UNSL-CH 0095, 0097, 0230; Ciudad de San Luis, UNSL-CH 0118, 0120, 0141, 0172, 0214, 0221; Ruta Prov. 3 (33°15'S; 66°18'W, UNSL-CH 0231, 0232. Dpto. Cnel. Pringles: La Florida (33°08'S; 66°02'W UNSL-CH 0223. Colectores: Juan Cruz Baldoni, Ana María Brigada, Matías García, Analía C. Guerreiro y Flavio Martínez.

  5. Inventario de recursos turísticos como base para la planificación territorial en la zona altiplano de san Luis Potosi, México

    Directory of Open Access Journals (Sweden)

    Paloma Blanco López

    2015-01-01

    Full Text Available Este artículo aborda el análisis del potencial turístico como condición para la planificación turística. Se explica el turismo como factor de desarrollo y a la planificación como instrumento de su gestión. Se utilizan los municipios con mayor potencial turístico en la Zona Altiplano de San Luis Potosí para exponer y ejemplificar los resultados del diagnóstico de la región. Después se evalúan los instrumentos vigentes de planificación turística vigentes en San Luis Potosí y se ofrece una propuesta de aprovechamiento turístico con ayuda de un análisis FODA para los municipios seleccionados.

  6. Innovations in Stream Restoration and Flood Control Design Meeting Flood Capacity and Environmental Goals on San Luis Obispo Creek

    Science.gov (United States)

    Wayne Peterson

    1989-01-01

    Can a natural flowing creek be increased in drainage capacity to protect an adjacent community from flooding while still maintaining a natural habitat? San Luis Obispo constructed one such project on over a mile of Creek as a part of a housing development. The City found that some of the mitigation measures included in the project worked while others did not. In the...

  7. Automated discovery systems and the inductivist controversy

    Science.gov (United States)

    Giza, Piotr

    2017-09-01

    The paper explores possible influences that some developments in the field of branches of AI, called automated discovery and machine learning systems, might have upon some aspects of the old debate between Francis Bacon's inductivism and Karl Popper's falsificationism. Donald Gillies facetiously calls this controversy 'the duel of two English knights', and claims, after some analysis of historical cases of discovery, that Baconian induction had been used in science very rarely, or not at all, although he argues that the situation has changed with the advent of machine learning systems. (Some clarification of terms machine learning and automated discovery is required here. The key idea of machine learning is that, given data with associated outcomes, software can be trained to make those associations in future cases which typically amounts to inducing some rules from individual cases classified by the experts. Automated discovery (also called machine discovery) deals with uncovering new knowledge that is valuable for human beings, and its key idea is that discovery is like other intellectual tasks and that the general idea of heuristic search in problem spaces applies also to discovery tasks. However, since machine learning systems discover (very low-level) regularities in data, throughout this paper I use the generic term automated discovery for both kinds of systems. I will elaborate on this later on). Gillies's line of argument can be generalised: thanks to automated discovery systems, philosophers of science have at their disposal a new tool for empirically testing their philosophical hypotheses. Accordingly, in the paper, I will address the question, which of the two philosophical conceptions of scientific method is better vindicated in view of the successes and failures of systems developed within three major research programmes in the field: machine learning systems in the Turing tradition, normative theory of scientific discovery formulated by Herbert Simon

  8. Tectonic Implications of Changes in the Paleogene Paleodrainage Network in the West-Central Part of the San Luis Basin, Northern Rio Grande Rift, New Mexico and Colorado, USA

    Science.gov (United States)

    Thompson, R. A.; Turner, K. J.; Cosca, M. A.; Drenth, B.

    2016-12-01

    The San Luis Basin is the largest of extensional basins in the northern Rio Grande rift (>11,400 km2). The modern basin configuration is the result of Neogene deformation that has been the focus of numerous studies. In contrast, Paleogene extensional deformation is relatively little studied owing to a fragmentary or poorly exposed stratigraphic record in most areas. However, volcanic and volcaniclastic deposits exposed along the western margin of the basin provide the spatial and temporal framework for interpretation of paleodrainage patterns that changed in direct response to Oligocene basin subsidence and the migration of centers of Tertiary volcanism. The early Oligocene (34 to 30 Ma) drainage pattern that originated in the volcanic highlands of the San Juan Mountains flowed south into the northern Tusas Mountains. A structural and topographic high composed of Proterozoic rocks in the Tusas Mountains directed flow to the southeast at least as late as 29 Ma, as ash-flow tuffs sourced in the southeast San Juan Mountains are restricted to the north side of the paleohigh. Construction of volcanic highlands in the San Luis Hills between 30 and 28.5 Ma provided an abundant source of volcanic debris that combined with volcanic detritus sourced in the southeast San Juan Mountains and was deposited (Los Pinos Formation) throughout the northern Tusas Mountains progressively onlapping the paleotopographic high. By 29 Ma, subsidence of the Las Mesitas graben, a structural sub-basin, between the San Luis Hills and the southeast San Juan and northern Tusas Mountains is reflected by thick deposits of Los Pinos Formation beneath 26.5 Ma basalts. Regional tectonism responsible for the formation of the graben may have also lowered the topographic and structural high in the Tusas Mountains, which allowed development of a southwest-flowing paleodrainage that likely flowed onto the Colorado Plateau. Tholeiitic basalt flows erupted in the San Luis Hills at 25.8 Ma, that presently cap

  9. Genetic diversity of the Mycobacterium tuberculosis complex in San Luis Potosí, México.

    Science.gov (United States)

    López-Rocha, Estela; Juárez-Álvarez, Julio; Riego-Ruiz, Lina; Enciso-Moreno, Leonor; Ortega-Aguilar, Francisco; Hernández-Nieto, Julián; Enciso-Moreno, José A; López-Revilla, Rubén

    2013-05-01

    Although epidemiologic and socioeconomic criteria and biomedical risk factors indicate high-priority for tuberculosis (TB) control in Mexico, molecular epidemiology studies of the disease in the country are scarce. Complete sociodemographic and clinical data were obtained from 248 of the 432 pulmonary TB (PTB) cases confirmed from 2006 to 2010 on the population under epidemiological surveillance in the state of San Luis Potosí, México. From most PTB cases with complete data Mycobacterium tuberculosis complex (MTC) isolates were recovered and their spoligotypes, lineages and families, geographic distribution and drug resistance determined. Pulmonary tuberculosis incidence ranged from 2.4 to 33.4 (cases per 100,000 inhabitants) in the six state sanitary jurisdictions that were grouped in regions of low (jurisdictions I-II-III), intermediate (jurisdictions IV-V) and high incidence (jurisdiction VI) with 6.2, 17.3 and 33.4 rates, respectively. Most patients were poor, 50-years-median-age males and housewives. Among the 237 MTC spoligotyped isolates, 232 corresponded to M. tuberculosis (104 spoligotypes in 24 clusters) and five to M. bovis. The predominant Euro-American lineage was distributed all over the state, the East-Asian lineage (Beijing family) in the capital city, the Indo-Oceanic (Manila family) in eastern localities, and M. bovis in rural localities. In San Luis Potosí TB affects mainly poor male adults and is caused by M. tuberculosis and to a minor extent by M. bovis. There is great genotypic diversity among M. tuberculosis strains, the Euro-American lineage being much more prevalent than the Indo-Oceanic and East-Asian lineages. The frequency of resistant strains is relatively low and not associated to any particular lineage.

  10. A Technique Socratic Questioning-Guided Discovery

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    M. Hakan Türkçapar

    2012-03-01

    Full Text Available “Socratic Method” is a way of teaching philosophical thinking and knowledge by asking questions which was used by antique period greek philosopher Socrates. Socrates was teaching knowledge to his followers by asking questions and the conversation between them was named “Socratic Dialogues”. In this meaning, no novel knowledge is taught to the individual but only what is formerly known is reminded and rediscovered. The form of socratic questioning which is used during the process of cognitive behavioral therapy is known as Guided Discovery. In this method it is aimed to make the client notice the piece of knowledge which he could notice but is not aware with a series of questions. Socratic method or guided discovery consists of several steps which are: Identifying the problem by listening to the client and making reflections, finding alternatives by examining and evaluating, reidentification by using the newly found information and questioning the old distorted belief and reaching to a conclusion and applying it. Question types used during these procedures are, questions for gaining information, questions revealing the meanings, questions revealing the beliefs, questions about behaviours during the similar past experiences, analyse questions and analytic synthesis questions. In order to make the patient feel understood it is important to be empathetic and summarising the problem during the interview. In this text, steps of Socratic Questioning-Guided Discovery will be reviewed with sample dialogues after each step

  11. Contradictions porteñas: modernity, modernism and modernization in Jorge Luis Borges during the 1920’s

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    Pedro Demenech

    2013-06-01

    Full Text Available The aim of the article is discuss the concepts of modernity, modernism and modernization from the propositions raised by Marshal Berman and Néstor García Canclini. The fierce transformation of Buenos Aires during the 1920’s will be the focus of the analysis. To this end, we use the work of argentine poet Jorge Luis Borges to comprehend the development of these processes in the urban space of Buenos Aires.

  12. On reliable discovery of molecular signatures

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    Björkegren Johan

    2009-01-01

    Full Text Available Abstract Background Molecular signatures are sets of genes, proteins, genetic variants or other variables that can be used as markers for a particular phenotype. Reliable signature discovery methods could yield valuable insight into cell biology and mechanisms of human disease. However, it is currently not clear how to control error rates such as the false discovery rate (FDR in signature discovery. Moreover, signatures for cancer gene expression have been shown to be unstable, that is, difficult to replicate in independent studies, casting doubts on their reliability. Results We demonstrate that with modern prediction methods, signatures that yield accurate predictions may still have a high FDR. Further, we show that even signatures with low FDR may fail to replicate in independent studies due to limited statistical power. Thus, neither stability nor predictive accuracy are relevant when FDR control is the primary goal. We therefore develop a general statistical hypothesis testing framework that for the first time provides FDR control for signature discovery. Our method is demonstrated to be correct in simulation studies. When applied to five cancer data sets, the method was able to discover molecular signatures with 5% FDR in three cases, while two data sets yielded no significant findings. Conclusion Our approach enables reliable discovery of molecular signatures from genome-wide data with current sample sizes. The statistical framework developed herein is potentially applicable to a wide range of prediction problems in bioinformatics.

  13. Saber mirar, saber contar. La narrativa cinematográfica de José Luis Borau

    OpenAIRE

    Mérida Donoso, José Antonio

    2018-01-01

    Tesis doctoral inédita leída en la Universidad Autónoma de Madrid, Facultad de Filosofía y Letras, Departamento de Filología Española. Fecha de lectura: 29-9-2017 La presente tesis doctoral se adentra en una de las figuras fundamentales de la historia del cine español, José Luis Borau. Para ello se analiza su cine desde una perspectiva textual, atendiendo al emisor, el receptor, el contexto –de producción y sociopolítico- y el texto fílmico. Bajo este prisma se ofrece una visión del estilo...

  14. Potential human health risk by 234,238U and 210Po due to consumption of fish from the "Luis L. Leon" reservoir (Northern Mexico)

    Science.gov (United States)

    Luna-Porres, M. Y.; Rodríguez-Villa, M. A.; Herrera-Peraza, E.; Cabral-Lares, M.; Renteria-Villalobos, M.; Montero-Cabrera, M. E.

    2014-07-01

    The Conchos River is one of the most important in northern Mexico and the main surface waterway in the arid state of Chihuahua. The Luis L. Leon dam produces the Luis L. Leon Reservoir, which is the last major reservoir before the Conchos River enters the Rio Grande at the Texas-Chihuahua border. Activity concentrations (AC) of 234,238U and 210Po in fillet and liver of three stocked fish species (Lepomis cyanellus, Cyprinus carpio and Ictalurus furcatus), as well as in water from the Luis L. Leon reservoir were determined. 238U and 234U ACs in fillet samples showed values of 0.007-0.014 and 0.01-0.02 Bq kg-1 wet weight (ww), respectively. Liver samples for Lepomis cyanellus, Cyprinus carpio and Ictalurus furcatus species, present 210Po AC of 1.16-3.26 0.70-1.13 and 0.93-1.37 Bqṡkg-1 ww. The elemental Bioaccumulation Factor (BAF) for fish tissues respect to their concentrations in water was determined. Lepomis cyanellus species showed the highest BAF for total uranium in fillet, with value 1.5. The annual effective dose for uranium in adults by fish consumption in this work ranged from 4.46×10-3 to 3.68×10-2 μSvṡyear-1. The difference in concentrations of uranium in fillet among the studied species is likely primarily due to their differences in diet and habitat.

  15. Guided Discovery with Socratic Questioning

    Directory of Open Access Journals (Sweden)

    M. Hakan Türkçapar

    2015-04-01

    Full Text Available “The Socratic method” is a way of teaching philosophical thinking and knowledge by asking questions. It was first used by in ancient times by the Greek philosopher Socrates who taught his followers by asking questions; these conversations between them are known as “Socratic dialogues”. In this methodology, no new knowledge is taught to the individual; rather, the individual is guided to remember and rediscover what was formerly known through this process. The main method used in cognitive therapy is guided discovery. There are various methods of guided discovery in cognitive therapy. The form of verbal exchange between the therapist and client which is used during the process of cognitive behavioral therapy is known as “socratic questioning”. In this method the goal is to make the client rediscover, with a series of questions, a piece of knowledge which he could otherwise know but is not presently conscious of. The Socratic Questioning consists of several steps, including: identifying the problem by listening to the client and making reflections, finding alternatives by examining and evaluating, reidentification by using the newly rediscovered information and questioning the old distorted belief, and reaching a new conclusion and applying it. Question types used during these procedures are: questions for collecting information, questions revealing meanings, questions revealing beliefs, questions about behaviours during similar past experiences, analytic questions and analytic synthesis questions. In order to make the patient feel understood, it is important to be empathetic and summarize the problem during the interview. In this text, steps of Socratic Questioning-Guided Discovery will be reviewed with sample dialogues provided for each step. [JCBPR 2015; 4(1.000: 47-53

  16. Predicting arsenic concentrations in groundwater of San Luis Valley, Colorado: implications for individual-level lifetime exposure assessment.

    Science.gov (United States)

    James, Katherine A; Meliker, Jaymie R; Buttenfield, Barbara E; Byers, Tim; Zerbe, Gary O; Hokanson, John E; Marshall, Julie A

    2014-08-01

    Consumption of inorganic arsenic in drinking water at high levels has been associated with chronic diseases. Risk is less clear at lower levels of arsenic, in part due to difficulties in estimating exposure. Herein we characterize spatial and temporal variability of arsenic concentrations and develop models for predicting aquifer arsenic concentrations in the San Luis Valley, Colorado, an area of moderately elevated arsenic in groundwater. This study included historical water samples with total arsenic concentrations from 595 unique well locations. A longitudinal analysis established temporal stability in arsenic levels in individual wells. The mean arsenic levels for a random sample of 535 wells were incorporated into five kriging models to predict groundwater arsenic concentrations at any point in time. A separate validation dataset (n = 60 wells) was used to identify the model with strongest predictability. Findings indicate that arsenic concentrations are temporally stable (r = 0.88; 95 % CI 0.83-0.92 for samples collected from the same well 15-25 years apart) and the spatial model created using ordinary kriging best predicted arsenic concentrations (ρ = 0.72 between predicted and observed validation data). These findings illustrate the value of geostatistical modeling of arsenic and suggest the San Luis Valley is a good region for conducting epidemiologic studies of groundwater metals because of the ability to accurately predict variation in groundwater arsenic concentrations.

  17. De Novo Discovery of Structured ncRNA Motifs in Genomic Sequences

    DEFF Research Database (Denmark)

    Ruzzo, Walter L; Gorodkin, Jan

    2014-01-01

    De novo discovery of "motifs" capturing the commonalities among related noncoding ncRNA structured RNAs is among the most difficult problems in computational biology. This chapter outlines the challenges presented by this problem, together with some approaches towards solving them, with an emphas...... on an approach based on the CMfinder CMfinder program as a case study. Applications to genomic screens for novel de novo structured ncRNA ncRNA s, including structured RNA elements in untranslated portions of protein-coding genes, are presented.......De novo discovery of "motifs" capturing the commonalities among related noncoding ncRNA structured RNAs is among the most difficult problems in computational biology. This chapter outlines the challenges presented by this problem, together with some approaches towards solving them, with an emphasis...

  18. THE SONG OF SONGS IN THE WORK OF LUIS DE LEON, SAN JUAN DE LA CRUZ Y JUAN GELMAN LANGUAGE, CHILDREN AND SPIRITUAL EXPERIENCE

    Directory of Open Access Journals (Sweden)

    Geneviève Fabry

    2015-04-01

    Full Text Available This paper aims to study the intertextual traces dell Song of Songs in the work of Luis de León, San Juan de la Cruz and Juan Gelman from a particular point of view: the resonance in the vernacular of small biblical book as founder dimension of an experience spiritual, emotional and literary time. Choosing our corpus may surprise but, for one, would like to emphasize the importance of two pivotal moments in the reception of the Song: the Spanish Renaissance, whose approach to the Bible is enriched by new currents philological and exegetical of which Luis de León is a sublime representative; the late twentieth century in which an insistent intertextuality observed with sanjuanista work in one direction often foreign to Christian spirituality, as in the case of the Argentine Juan Gelman.

  19. Volatility Discovery

    DEFF Research Database (Denmark)

    Dias, Gustavo Fruet; Scherrer, Cristina; Papailias, Fotis

    The price discovery literature investigates how homogenous securities traded on different markets incorporate information into prices. We take this literature one step further and investigate how these markets contribute to stochastic volatility (volatility discovery). We formally show...... that the realized measures from homogenous securities share a fractional stochastic trend, which is a combination of the price and volatility discovery measures. Furthermore, we show that volatility discovery is associated with the way that market participants process information arrival (market sensitivity......). Finally, we compute volatility discovery for 30 actively traded stocks in the U.S. and report that Nyse and Arca dominate Nasdaq....

  20. José Teruel, Los años norteamericanos de Luis Cernuda: una singular propuesta de lectura

    Directory of Open Access Journals (Sweden)

    Dana Guisasola

    2014-07-01

    Full Text Available La presente reseña se aboca al reciente libro de José Teruel, Los años norteamericanos de Luis Cernuda. El crítico revisa un abundante material bibliográfico y da cuenta de  los pormenores de la vida y obra del poeta español entre 1947 -año en el que el poeta llega a Nueva Inglaterra- y 1963, año de su muerte. El libro ha sido galardonado con el Premio de Investigación Literaria Gerardo Diego en 2013.

  1. New K-Ar ages of volcanic rocks and associated mineralization in Canada Honda district, San Luis, Argentina

    International Nuclear Information System (INIS)

    Urbina, N.E.; Oggier, F.P

    2001-01-01

    New K-Ar ages in the Late Tertiary gold-bearing volcanic belt of the Sierras Pampeanas of San Luis, Argentina are presented. At Canada Honda district, an age of 8.49±0.2 Ma yielded by Cerro del Valle andesite indicates that the dome emplacement postdates the Diente Verde eruptive event. An even younger age of 7.3±0.2 Ma was obtained for illite from hydrothermal alteration at La Reynela mineralization which is hosted by Cerro del Valle andesite (au)

  2. A forgotten chapter of Mexican technology and science: Luis Gutiérrez Villegas and poliomyelitis in Mexico.

    Science.gov (United States)

    Velázquez-Arellano, Antonio

    Two different types of vaccines were developed against poliomyelitis: The Salk vaccine using inactivated virus and the Sabin one, that was used later, after investigations assured its safety. The first one was made in Mexico with its own resources since 1957 thanks to the efforts of young researchers and technicians coordinated by Luis Gutiérrez-Villegas, M.D., who was a Clinical Pathologist, University Professor and President of the Mexican National Academy of Mexico. Copyright: © 2017 SecretarÍa de Salud.

  3. Problems in the Science and Mathematics of 'The Logic of Scientific Discovery'

    Directory of Open Access Journals (Sweden)

    Alan B. Whiting

    2012-11-01

    Full Text Available Professor Sir Karl Popper (1902-1994 was one of the most influential philosophers of science of the twentieth century. However, in his most famous work 'The Logic of Scientific Discovery' he displays troubling misunderstandings of science and mathematics at a basic level. These call into question his conclusions concerning the philosophy of science. Quanta 2012; 1: 13–18.

  4. Los hongos poliporoides de la Huasteca Potosina, San Luis Potosí, México

    Directory of Open Access Journals (Sweden)

    Victor I. Alvarez

    2016-03-01

    Full Text Available Se estudiaron 98 especies de hongos poliporoides basados en 358 especímenes procedentes de 15 localidades de nueve municipios de la Huasteca Potosina en el estado de San Luis Potosí. Las 98 especies se clasifican en tres órdenes de Agaricomycetes, el orden Gloeophyllales con una familia, un género y  una especie, el orden Hymenochaetales con 2 familias, 10 géneros y 33 especies, y el orden Polyporales con seis familias,  32 géneros y 64 especies. De éstas, 73 se citan por primera vez para el estado, incluidas Phellinus calcitratus, P. coffeatoporus y Ceriporia reticulata que son nuevos registros para México.Palabras clave: Gloeophyllales, Hymenochaetales, Polyporales, macrohongos xilófagos.

  5. Genetic diversity of the Mycobacterium tuberculosis Complex in San Luis Potosí, México

    Science.gov (United States)

    2013-01-01

    Background Although epidemiologic and socioeconomic criteria and biomedical risk factors indicate high-priority for tuberculosis (TB) control in Mexico, molecular epidemiology studies of the disease in the country are scarce. Methods Complete sociodemographic and clinical data were obtained from 248 of the 432 pulmonary TB (PTB) cases confirmed from 2006 to 2010 on the population under epidemiological surveillance in the state of San Luis Potosí, México. From most PTB cases with complete data Mycobacterium tuberculosis complex (MTC) isolates were recovered and their spoligotypes, lineages and families, geographic distribution and drug resistance determined. Results Pulmonary tuberculosis incidence ranged from 2.4 to 33.4 (cases per 100,000 inhabitants) in the six state sanitary jurisdictions that were grouped in regions of low (jurisdictions I-II-III), intermediate (jurisdictions IV-V) and high incidence (jurisdiction VI) with 6.2, 17.3 and 33.4 rates, respectively. Most patients were poor, 50-years-median-age males and housewives. Among the 237 MTC spoligotyped isolates, 232 corresponded to M. tuberculosis (104 spoligotypes in 24 clusters) and five to M. bovis. The predominant Euro-American lineage was distributed all over the state, the East-Asian lineage (Beijing family) in the capital city, the Indo-Oceanic (Manila family) in eastern localities, and M. bovis in rural localities. Conclusions In San Luis Potosí TB affects mainly poor male adults and is caused by M. tuberculosis and to a minor extent by M. bovis. There is great genotypic diversity among M. tuberculosis strains, the Euro-American lineage being much more prevalent than the Indo-Oceanic and East-Asian lineages. The frequency of resistant strains is relatively low and not associated to any particular lineage. PMID:23635381

  6. 1959: los intentos de derrocamiento de las dictaduras de Trujillo, Stroessner y Luis Somoza

    Directory of Open Access Journals (Sweden)

    María Dolores Ferrero Blanco

    2016-03-01

    Full Text Available El triunfo de la revolución cubana trajo, entre sus múltiples consecuencias, la reanimación de la oposición a las tres dictaduras fuertes en 1959: la República Dominicana, Nicaragua y Paraguay. En el presente artículo se analizan las características generales de las mismas, los paralelismos y diferencias entre Trujillo, Stroessner y Somoza, al tiempo que se exponen los diversos intentos de los opositores exiliados para acabar con los regímenes tiránicos implantados en sus respectivos países. Las fuentes utilizadas proceden de los archivos nacionales y de relaciones exteriores, especialmente la documentación diplomática, que aporta una visión singular de los embajadores dependiendo de los destinos. Palabras clave: Rafael Leónidas Trujillo, Luis Somoza, Alfredo Stroessner, dictaduras iberoamericanas, revolución cubana, oposición a las dictaduras._______________________________Abstract: Cuban revolution success brought, among its multiple consequences, the liveliness of the political opposition against the three dictatorships in 1959: the Dominican Republic, Nicaragua and Paraguay. In the present article it is analyzed their general characteristics of the same ones, the differences between Trujillo, Stroessner and the Somoza's, as same as it is exposed the several attempts of the exiles op-ponents to end the implanted tyrannies' regimes in their respective countries. The sources used come from the national archives and foreign relations, especially the diplomatic docu-mentation, that contributes with a singular vision of the ambassadors depending on their destinies, an optics that serves us to know the relations established between the three dictators.Keywords: Rafael Leónidas Trujillo, Luis Somoza, Alfredo Stroessner, latinoamerican dictatorships, Cuban Revolution, dictatorships political opposition.    

  7. Presence of exotic birds in San Luis Potosi city, Mexican Plateau

    Directory of Open Access Journals (Sweden)

    Ramírez-Albores, J.E.

    2015-01-01

    Full Text Available We recorded 12 exotic bird species in San Luis Potosi, Mexico and adjacent areas. Obtained data were collected during the period August 2012 to August 2013. From the total of recorded species, eight are confirmations (Anas platyrhynchos domesticus, Cairina moschata, Bubulcus ibis, Columba livia, Sturnus vulgaris, Turdus rufopalliatus, Quiscalus mexicanus and Passer domesticus and four are new records (Aratinga canicularis, Amazona oratrix, A. autumnalis and Cyanocorax yncas. Although not all exotic species represent a risk because of the lack of the necessary resources for the establishment of abundant viable populations, it is important to publicize their status in the region. Therefore, knowing the presence of exotic species in a new distribution area is important for monitoring its establishment and colonization, and defining management, control and eradication programs of these species, along with environmental education programs that would lead to a better understanding of impacts that these species can cause.

  8. Petrological and geochemical characterization of the plutonic rocks of the Sierra de La Aguada, Province of San Luis, Argentina: Genetic implications with the Famatinian magmatic arc

    Directory of Open Access Journals (Sweden)

    E. Cristofolini

    2017-07-01

    Full Text Available This study presents a synthesis on the geology of the crystalline complex that constitute the Sierra de la Aguada, San Luis province, Argentine, from an approach based on field relations, petrologic and structural features and geochemical characteristic. This mountain range exposes a basement dominated by intermediate to mafic calcalkaline igneous rocks and peraluminous felsic granitoids, both emplaced in low to medium grade metamorphic rocks stabilized under low amphibolite facies. All this lithological terrane has been grouped in the El Carrizal-La Aguada Complex. Field relations, petrographic characterization and geochemical comparison of the plutonic rocks from the study area with those belonging to the Ordovician Famatinian suit exposed in the Sierra Grande de San Luis, suggest a genetic and temporal relation linked to the development of the Famatinian magmatic arc.

  9. Clima y compromiso organizacional en una mediana empresa manufacturera de San Luis Potosí, S.L.P.

    OpenAIRE

    Crespo Bravo, Carolina

    2016-01-01

    Este trabajo tiene como objetivo principal analizar la relación que existe entre clima y compromiso organizacional y de estos con las características personales. La muestra se integró con 80 trabajadores de una mediana empresa manufacturera ubicada en la ciudad de San Luis Potosí. Se realizó un estudio empírico transversal aplicando cuestionarios para clima organizacional de Araujo et al. (2011), el cual se construyó con características inherentes a las dimensiones: a) estilo de geren...

  10. «In favor of happiness»: the legacy of the Enlightenment in the poetry of Luis García Montero «Partidario de la felicidad»: el horizonte de la Ilustración en la poesía de Luis García Montero

    Directory of Open Access Journals (Sweden)

    Araceli IRAVEDRA

    2012-06-01

    Full Text Available The most celebrated book of Luis García Montero, Habitaciones separadas (1994, includes a dramatic monologue starring the figure of Jovellanos. Far from an anectodal fact, the presence of the asturian intellectual in this point of the lyric biography of García Montero comes to ratify the importance that the enlightened tradition has acquired in the poetic system of the author from Granada, main theoretical mentor of the so called poetry of experience. Following the reading suggested by Luis García Montero, we systematize the enlightened foundations of this aesthetic trend, which would find its modern roots in some capital notions of the eighteen century doctrine. Furthermore, we attempt to show how far those enlightened categories finally conform an axiological canon and reinforce García Montero’s theoretical opinion in favour of the value of the trade as an effective intervention of the poet in the social order. Finally, we suggest an interpretation of the «El insomnio de Jovellanos» in the light of the enlightened reading of the Modernity that the poet postulates in his essayistic discourse, a Modernity aimed to the transformation of the present against the repeated decrees of the end of History.El libro tal vez más celebrado de Luis García Montero, Habitaciones separadas (1994, incorpora un monólogo dramático protagonizado por la figura de Jovellanos. Lejos de tratarse de un dato anecdótico, la compañía del asturiano en este punto de la biografía lírica de García Montero no viene sino a rubricar el predicamento que la tradición ilustrada ha conquistado en el sistema poético del autor granadino, principal mentor teórico de la llamada poesía de la experiencia. A la zaga de la lectura propuesta por Luis García Montero, efectuamos una sistematización de los fundamentos ilustrados de dicha corriente estética, que hallaría sus raíces modernas en algunas nociones capitales de la preceptiva dieciochesca. Además, tratamos

  11. Reinventing Discovery Learning: A Field-Wide Research Program

    Science.gov (United States)

    Abrahamson, Dor; Kapur, Manu

    2018-01-01

    Whereas some educational designers believe that students should learn new concepts through explorative problem solving within dedicated environments that constrain key parameters of their search and then support their progressive appropriation of empowering disciplinary forms, others are critical of the ultimate efficacy of this discovery-based…

  12. Jorge Luis Borges at two final judgments

    Directory of Open Access Journals (Sweden)

    Gustavo Ponciano Cunha de Oliveira

    2017-06-01

    Full Text Available Em 1988, Beatriz Sarlo propõe uma passagem entre duas poéticas em Jorge Luis Borges: de Evaristo Carriego (1930 em direção a Historia universal de la infamia (1935. Os dois textos são “insidiosos”, defende a pesquisadora, porque falsificam as biografias de seus personagens. Porém, a coletânea de 1935 opera em âmbito universal. Este movimento, afirma Sarlo, é portador de um acumulo de prerrogativas, associado à dupla inscrição de Borges: o cidadão do mundo e, simultaneamente, o de um país pensado a partir de Buenos Aires. Neste ensaio, sugerimos uma passagem anterior, evidenciada em “Sentirse en muerte” (1928: do criollismo – o poeta dos arrabaldes, dotado da capacidade de transporte sensível e instalado nos limites de sua cidade imaginada, que busca a representação poética digna de seu conceito de argentinidade – em direção à prosa que alcança o caráter argumentativo-reflexivo dos ensaios sobre o tempo e a eternidade característicos de Borges, início de sua legitimação como “percibidor abstracto del mundo”. Este movimento é também portador de um acúmulo de prerrogativas, dupla inscrição de Borges: como poeta, literato e ensaísta programático do criollismo; como meditador dedicado aos assombros contidos em nossos conceitos de vida, tempo e universo, operador de textos da Filosofia e da Teologia.

  13. Un precedente de psicología conductual en la Universidad Nacional de San Luis (Argentina)

    OpenAIRE

    Calabresi, Corina; Polanco, Fernando

    2008-01-01

    En 1970 un grupo de estudiantes de la Licenciatura en Psicología y Pedagogía de la Universidad Nacional de San Luis, Argentina, tuvo un activo compromiso con el desarrollo de una psicología científica basada en la teoría conductual. El trabajo analiza la conformación de dicho movimiento estudiantil y la fundación, por parte del mismo, en 1974 del Centro de Estudios de Psicología Objetiva I. P. Pavlov (CEDEPO), el cual progresivamente cuestionó la hegemonía psicoanalítica en el medio académico...

  14. Discovery as a process

    Energy Technology Data Exchange (ETDEWEB)

    Loehle, C.

    1994-05-01

    The three great myths, which form a sort of triumvirate of misunderstanding, are the Eureka! myth, the hypothesis myth, and the measurement myth. These myths are prevalent among scientists as well as among observers of science. The Eureka! myth asserts that discovery occurs as a flash of insight, and as such is not subject to investigation. This leads to the perception that discovery or deriving a hypothesis is a moment or event rather than a process. Events are singular and not subject to description. The hypothesis myth asserts that proper science is motivated by testing hypotheses, and that if something is not experimentally testable then it is not scientific. This myth leads to absurd posturing by some workers conducting empirical descriptive studies, who dress up their study with a ``hypothesis`` to obtain funding or get it published. Methods papers are often rejected because they do not address a specific scientific problem. The fact is that many of the great breakthroughs in silence involve methods and not hypotheses or arise from largely descriptive studies. Those captured by this myth also try to block funding for those developing methods. The third myth is the measurement myth, which holds that determining what to measure is straightforward, so one doesn`t need a lot of introspection to do science. As one ecologist put it to me ``Don`t give me any of that philosophy junk, just let me out in the field. I know what to measure.`` These myths lead to difficulties for scientists who must face peer review to obtain funding and to get published. These myths also inhibit the study of science as a process. Finally, these myths inhibit creativity and suppress innovation. In this paper I first explore these myths in more detail and then propose a new model of discovery that opens the supposedly miraculous process of discovery to doser scrutiny.

  15. CONTRIBUTIONS TO RICKETTSIOSES RESEARCH IN COLOMBIA (1917-1943), LUIS B. PATIÑO CAMARGO

    Science.gov (United States)

    FACCINI-MARTÍNEZ, Álvaro A.; BOTERO-GARCÍA, Carlos A.; HIDALGO, Marylin

    2016-01-01

    Colombian physician Luis Benigno Patiño Camargo was one of the pioneers in the study of rickettsioses in South America, demonstrating for the first time in Colombia the presence of Rickettsia rickettsii as the etiological agent of a highly deadly exanthematic febrile syndrome in the 1930s. However, Patiño-Camargo performed other investigations from 1917-1943, which represent the first descriptions and scientific evidence of the presence of R. prowazekii and R. typhi in Colombia. Almost 60 years after the latest research conducted by Dr. Patiño-Camargo, rickettsioses were again a matter of interest and research. In the last decade over 20 research studies have been published, showing new endemic areas for R. rickettsii, as well as the description of new rickettsial species in Colombia. PMID:27074327

  16. Reconstructing Sessions from Data Discovery and Access Logs to Build a Semantic Knowledge Base for Improving Data Discovery

    Directory of Open Access Journals (Sweden)

    Yongyao Jiang

    2016-04-01

    Full Text Available Big geospatial data are archived and made available through online web discovery and access. However, finding the right data for scientific research and application development is still a challenge. This paper aims to improve the data discovery by mining the user knowledge from log files. Specifically, user web session reconstruction is focused upon in this paper as a critical step for extracting usage patterns. However, reconstructing user sessions from raw web logs has always been difficult, as a session identifier tends to be missing in most data portals. To address this problem, we propose two session identification methods, including time-clustering-based and time-referrer-based methods. We also present the workflow of session reconstruction and discuss the approach of selecting appropriate thresholds for relevant steps in the workflow. The proposed session identification methods and workflow are proven to be able to extract data access patterns for further pattern analyses of user behavior and improvement of data discovery for more relevancy data ranking, suggestion, and navigation.

  17. Visual Resource Analysis for Solar Energy Zones in the San Luis Valley

    Energy Technology Data Exchange (ETDEWEB)

    Sullivan, Robert [Argonne National Laboratory (ANL), Argonne, IL (United States). Environmental Science Division; Abplanalp, Jennifer M. [Argonne National Laboratory (ANL), Argonne, IL (United States). Environmental Science Division; Zvolanek, Emily [Argonne National Laboratory (ANL), Argonne, IL (United States). Environmental Science Division; Brown, Jeffery [Bureau of Land Management, Washington, DC (United States). Dept. of the Interior

    2016-01-01

    This report summarizes the results of a study conducted by Argonne National Laboratory’s (Argonne’s) Environmental Science Division for the U.S. Department of the Interior Bureau of Land Management (BLM). The study analyzed the regional effects of potential visual impacts of solar energy development on three BLM-designated solar energy zones (SEZs) in the San Luis Valley (SLV) in Colorado, and, based on the analysis, made recommendations for or against regional compensatory mitigation to compensate residents and other stakeholders for the potential visual impacts to the SEZs. The analysis was conducted as part of the solar regional mitigation strategy (SRMS) task conducted by BLM Colorado with assistance from Argonne. Two separate analyses were performed. The first analysis, referred to as the VSA Analysis, analyzed the potential visual impacts of solar energy development in the SEZs on nearby visually sensitive areas (VSAs), and, based on the impact analyses, made recommendations for or against regional compensatory mitigation. VSAs are locations for which some type of visual sensitivity has been identified, either because the location is an area of high scenic value or because it is a location from which people view the surrounding landscape and attach some level of importance or sensitivity to what is seen from the location. The VSA analysis included both BLM-administered lands in Colorado and in the Taos FO in New Mexico. The second analysis, referred to as the SEZ Analysis, used BLM visual resource inventory (VRI) and other data on visual resources in the former Saguache and La Jara Field Offices (FOs), now contained within the San Luis Valley FO (SLFO), to determine whether the changes in scenic values that would result from the development of utility-scale solar energy facilities in the SEZs would affect the quality and quantity of valued scenic resources in the SLV region as a whole. If the regional effects were judged to be significant, regional

  18. The web server of IBM's Bioinformatics and Pattern Discovery group: 2004 update.

    Science.gov (United States)

    Huynh, Tien; Rigoutsos, Isidore

    2004-07-01

    In this report, we provide an update on the services and content which are available on the web server of IBM's Bioinformatics and Pattern Discovery group. The server, which is operational around the clock, provides access to a large number of methods that have been developed and published by the group's members. There is an increasing number of problems that these tools can help tackle; these problems range from the discovery of patterns in streams of events and the computation of multiple sequence alignments, to the discovery of genes in nucleic acid sequences, the identification--directly from sequence--of structural deviations from alpha-helicity and the annotation of amino acid sequences for antimicrobial activity. Additionally, annotations for more than 130 archaeal, bacterial, eukaryotic and viral genomes are now available on-line and can be searched interactively. The tools and code bundles continue to be accessible from http://cbcsrv.watson.ibm.com/Tspd.html whereas the genomics annotations are available at http://cbcsrv.watson.ibm.com/Annotations/.

  19. The Outreach Process in the Technical University Luis Vargas Torres, Esmeraldas, Ecuador

    Directory of Open Access Journals (Sweden)

    Harold Oyarvide-Ramirez

    2016-06-01

    Full Text Available As part of the transformative process that takes place in the ecuadorian university is research that aims to improve the outreach model at the Technical University Luis Vargas Torres Esmeraldas developed. The need of jobs forces people to venture into small businesses, however, this process is done in an empirical way, without sufficient technical and administrative knowledge that will enable the company to manage efficiently and obtain funding sources. Hence the relevance of the study, which allows guide and train the business sector in order to conduct an efficient management and create new businesses that operate as a means for the transformation of the productive matrix. The research results are: the structure and function of outreach model, the key elements that support the creation of the Center for Business Development and Entrepreneurship Support and the socioeconomic impact achieved from the development of relations among universities, businesses and government.

  20. Luis Álvarez-Gaumé to speak at El Ser Creativo 2011

    CERN Multimedia

    Jordan Juras

    2011-01-01

    During the weekend of 19 October, 2011, Madrid will host this year’s El Ser Creativo – a three-day conference celebrating new ideas that can change the world.   Over the course of the conference, 21 speakers will have the chance to share their opinions and ideas for 21 minutes each – the estimated time that the human brain is able to maintain complete focus. Among the Nobel Prize winners, scientists, doctors, and thinkers invited to this year's conference is Luis Álvarez-Gaumé, a theoretical physicist at CERN. Having made significant contributions to the understanding of gravitation, minimal supergravity theory and supersymmetry, Álvarez-Gaumé was an obvious choice to be invited to share his thoughts about the theory and reality of current physics ideas with the conference attendees. A webcast will be available to stream the entire conference live.

  1. The archaeological investigations of 1984 at Trinca “Izvorul lui Luca” site

    Directory of Open Access Journals (Sweden)

    Oleg Leviţki

    2017-09-01

    Full Text Available The article presents the archaeological researches carried out at Trinca “Izvorul lui Luca” settlement in 1984. The paper is part of the series of articles initiated by the authors in order to include the research results of this unusual site. The discovered archaeological remains were treated in a complex way, presented on layers, complexes, categories and types. Thus, the discovered complexes were described, the pieces of inventory systematized according to the categories of materials from which they were made, while the ceramics is presented by categories, types and variants. The most relevant findings have been analysed in more detail, being related to those specific of other synchronous or partially synchronic neighbouring cultures. As a result, the existence of a set of artefacts has been established, having analogies in the Hallstattian Carpathian-Nistrian cultural environment and, respectively, in the Middle Danube area.

  2. Synthesis-Spectroscopy Roadmap Problems: Discovering Organic Chemistry

    Science.gov (United States)

    Kurth, Laurie L.; Kurth, Mark J.

    2014-01-01

    Organic chemistry problems that interrelate and integrate synthesis with spectroscopy are presented. These synthesis-spectroscopy roadmap (SSR) problems uniquely engage second-year undergraduate organic chemistry students in the personal discovery of organic chemistry. SSR problems counter the memorize-or-bust strategy that many students tend to…

  3. [Artificial Intelligence in Drug Discovery].

    Science.gov (United States)

    Fujiwara, Takeshi; Kamada, Mayumi; Okuno, Yasushi

    2018-04-01

    According to the increase of data generated from analytical instruments, application of artificial intelligence(AI)technology in medical field is indispensable. In particular, practical application of AI technology is strongly required in "genomic medicine" and "genomic drug discovery" that conduct medical practice and novel drug development based on individual genomic information. In our laboratory, we have been developing a database to integrate genome data and clinical information obtained by clinical genome analysis and a computational support system for clinical interpretation of variants using AI. In addition, with the aim of creating new therapeutic targets in genomic drug discovery, we have been also working on the development of a binding affinity prediction system for mutated proteins and drugs by molecular dynamics simulation using supercomputer "Kei". We also have tackled for problems in a drug virtual screening. Our developed AI technology has successfully generated virtual compound library, and deep learning method has enabled us to predict interaction between compound and target protein.

  4. Usability Test Results for a Discovery Tool in an Academic Library

    Directory of Open Access Journals (Sweden)

    Jody Condit Fagan

    2008-03-01

    Full Text Available Discovery tools are emerging in libraries. These tools offer library patrons the ability to concurrently search the library catalog and journal articles. While vendors rush to provide feature-rich interfaces and access to as much content as possible, librarians wonder about the usefulness of these tools to library patrons. In order to learn about both the utility and usability of EBSCO Discovery Service, James Madison University conducted a usability test with eight students and two faculty members. The test consisted of nine tasks focused on common patron requests or related to the utility of specific discovery tool features. Software recorded participants’ actions and time on task, human observers judged the success of each task, and a post-survey questionnaire gathered qualitative feedback and comments from the participants.  Overall, participants were successful at most tasks, but specific usability problems suggested some interface changes for both EBSCO Discovery Service and JMU’s customizations of the tool.  The study also raised several questions for libraries above and beyond any specific discovery tool interface, including the scope and purpose of a discovery tool versus other library systems, working with the large result sets made possible by discovery tools, and navigation between the tool and other library services and resources.  This article will be of interest to those who are investigating discovery tools, selecting products, integrating discovery tools into a library web presence, or performing evaluations of similar systems.

  5. Quentin Skinner, Staten og friheten. Oslo: Res Publica, 2011. José Luis Martí and Philip Pettit, A Political Philosophy in Public Life. Civic Republicanism in Zapatero's Spain. Princeton: Princeton University Press, 2010 (Simon Laumann Jørgensen)

    DEFF Research Database (Denmark)

    Jørgensen, Simon Laumann

    2012-01-01

    Anmeldelse af Quentin Skinner, Staten og friheten, Oslo: Res Publica 2011, 199 NOK & José Luis Martí & Philip Pettit, A Political Philosophy in Public Life. Civic Republicanism in Zapatero’s Spain, Princeton: Princeton University Press 2010, $ 24.95......Anmeldelse af Quentin Skinner, Staten og friheten, Oslo: Res Publica 2011, 199 NOK & José Luis Martí & Philip Pettit, A Political Philosophy in Public Life. Civic Republicanism in Zapatero’s Spain, Princeton: Princeton University Press 2010, $ 24.95...

  6. Translational Research 2.0: a framework for accelerating collaborative discovery.

    Science.gov (United States)

    Asakiewicz, Chris

    2014-05-01

    The world wide web has revolutionized the conduct of global, cross-disciplinary research. In the life sciences, interdisciplinary approaches to problem solving and collaboration are becoming increasingly important in facilitating knowledge discovery and integration. Web 2.0 technologies promise to have a profound impact - enabling reproducibility, aiding in discovery, and accelerating and transforming medical and healthcare research across the healthcare ecosystem. However, knowledge integration and discovery require a consistent foundation upon which to operate. A foundation should be capable of addressing some of the critical issues associated with how research is conducted within the ecosystem today and how it should be conducted for the future. This article will discuss a framework for enhancing collaborative knowledge discovery across the medical and healthcare research ecosystem. A framework that could serve as a foundation upon which ecosystem stakeholders can enhance the way data, information and knowledge is created, shared and used to accelerate the translation of knowledge from one area of the ecosystem to another.

  7. Knowledge discovery with classification rules in a cardiovascular dataset.

    Science.gov (United States)

    Podgorelec, Vili; Kokol, Peter; Stiglic, Milojka Molan; Hericko, Marjan; Rozman, Ivan

    2005-12-01

    In this paper we study an evolutionary machine learning approach to data mining and knowledge discovery based on the induction of classification rules. A method for automatic rules induction called AREX using evolutionary induction of decision trees and automatic programming is introduced. The proposed algorithm is applied to a cardiovascular dataset consisting of different groups of attributes which should possibly reveal the presence of some specific cardiovascular problems in young patients. A case study is presented that shows the use of AREX for the classification of patients and for discovering possible new medical knowledge from the dataset. The defined knowledge discovery loop comprises a medical expert's assessment of induced rules to drive the evolution of rule sets towards more appropriate solutions. The final result is the discovery of a possible new medical knowledge in the field of pediatric cardiology.

  8. Ciudades invisibles. Tijuana en la obra de Federico Campbell, Luis Humberto Crosthwaite, Francisco Morales y Heriberto Yépez

    Directory of Open Access Journals (Sweden)

    Diana Palaversich

    2014-06-01

    This essay employs the concepts of “the haunted place” (Michel de Certeau and “the sense of place” (Kent Ryden to examine the representation of the US-Mexico border in the works of Federico Campbell, Luis Humberto Crosthwaite, Francisco Morales and Heriberto Yépez. While Campbell, Crosthwaite, and Morales represent Tijuana as a place imbued with personal and collective history, Yépez, in his most recent novel, Al otro lado, offers an apocalyptic vision of this border city, defined by narcoviolence, illegal immigration, and militarization.

  9. «In favor of happiness»: the legacy of the Enlightenment in the poetry of Luis García Montero

    Directory of Open Access Journals (Sweden)

    Araceli IRAVEDRA

    2012-02-01

    Full Text Available The most celebrated book of Luis García Montero, Habitaciones separadas (1994, includes a dramatic monologue starring the figure of Jovellanos. Far from an anectodal fact, the presence of the asturian intellectual in this point of the lyric biography of García Montero comes to ratify the importance that the enlightened tradition has acquired in the poetic system of the author from Granada, main theoretical mentor of the so called poetry of experience. Following the reading suggested by Luis García Montero, we systematize the enlightened foundations of this aesthetic trend, which would find its modern roots in some capital notions of the eighteen century doctrine. Furthermore, we attempt to show how far those enlightened categories finally conform an axiological canon and reinforce García Montero’s theoretical opinion in favour of the value of the trade as an effective intervention of the poet in the social order. Finally, we suggest an interpretation of the «El insomnio de Jovellanos» in the light of the enlightened reading of the Modernity that the poet postulates in his essayistic discourse, a Modernity aimed to the transformation of the present against the repeated decrees of the end of History.

  10. Introduction to the special collection of papers on the San Luis Basin Sustainability Metrics Project: a methodology for evaluating regional sustainability.

    Science.gov (United States)

    Heberling, Matthew T; Hopton, Matthew E

    2012-11-30

    This paper introduces a collection of four articles describing the San Luis Basin Sustainability Metrics Project. The Project developed a methodology for evaluating regional sustainability. This introduction provides the necessary background information for the project, description of the region, overview of the methods, and summary of the results. Although there are a multitude of scientifically based sustainability metrics, many are data intensive, difficult to calculate, and fail to capture all aspects of a system. We wanted to see if we could develop an approach that decision-makers could use to understand if their system was moving toward or away from sustainability. The goal was to produce a scientifically defensible, but straightforward and inexpensive methodology to measure and monitor environmental quality within a regional system. We initiated an interdisciplinary pilot project in the San Luis Basin, south-central Colorado, to test the methodology. The objectives were: 1) determine the applicability of using existing datasets to estimate metrics of sustainability at a regional scale; 2) calculate metrics through time from 1980 to 2005; and 3) compare and contrast the results to determine if the system was moving toward or away from sustainability. The sustainability metrics, chosen to represent major components of the system, were: 1) Ecological Footprint to capture the impact and human burden on the system; 2) Green Net Regional Product to represent economic welfare; 3) Emergy to capture the quality-normalized flow of energy through the system; and 4) Fisher information to capture the overall dynamic order and to look for possible regime changes. The methodology, data, and results of each metric are presented in the remaining four papers of the special collection. Based on the results of each metric and our criteria for understanding the sustainability trends, we find that the San Luis Basin is moving away from sustainability. Although we understand

  11. A Framework for Automatic Web Service Discovery Based on Semantics and NLP Techniques

    Directory of Open Access Journals (Sweden)

    Asma Adala

    2011-01-01

    Full Text Available As a greater number of Web Services are made available today, automatic discovery is recognized as an important task. To promote the automation of service discovery, different semantic languages have been created that allow describing the functionality of services in a machine interpretable form using Semantic Web technologies. The problem is that users do not have intimate knowledge about semantic Web service languages and related toolkits. In this paper, we propose a discovery framework that enables semantic Web service discovery based on keywords written in natural language. We describe a novel approach for automatic discovery of semantic Web services which employs Natural Language Processing techniques to match a user request, expressed in natural language, with a semantic Web service description. Additionally, we present an efficient semantic matching technique to compute the semantic distance between ontological concepts.

  12. Web-scale discovery in an academic health sciences library: development and implementation of the EBSCO Discovery Service.

    Science.gov (United States)

    Thompson, Jolinda L; Obrig, Kathe S; Abate, Laura E

    2013-01-01

    Funds made available at the close of the 2010-11 fiscal year allowed purchase of the EBSCO Discovery Service (EDS) for a year-long trial. The appeal of this web-scale discovery product that offers a Google-like interface to library resources was counter-balanced by concerns about quality of search results in an academic health science setting and the challenge of configuring an interface that serves the needs of a diverse group of library users. After initial configuration, usability testing with library users revealed the need for further work before general release. Of greatest concern were continuing issues with the relevance of items retrieved, appropriateness of system-supplied facet terms, and user difficulties with navigating the interface. EBSCO has worked with the library to better understand and identify problems and solutions. External roll-out to users occurred in June 2012.

  13. Masculinidad y violencia en el nuevo cine mexicano. Las películas de Luis Estrada

    Directory of Open Access Journals (Sweden)

    Claudia Elizabeth Puente

    2016-01-01

    Full Text Available En este artículo exploraremos la conformación de las masculinidades a través de las representaciones cinematográficas en América latina, específicamente en la obra del mexicano Luis Estrada, parte fundamental del llamado Nuevo cine mexicano en sus obras exhibidas entre 1999 y 2010. Aunque el universo de estudios de masculinidades es cada vez más amplio, las representaciones cinematográficas no han sidomuy exploradas. Este artículo pretende hacer un análisis de las representaciones masculinas y su relación con las representaciones femeninas en el nuevo cine mexicano en un contexto de violencia desde una perspectiva crítica feminista.

  14. A Cross-Layer Route Discovery Framework for Mobile Ad Hoc Networks

    Directory of Open Access Journals (Sweden)

    Wu Jieyi

    2005-01-01

    Full Text Available Most reactive routing protocols in MANETs employ a random delay between rebroadcasting route requests (RREQ in order to avoid "broadcast storms." However this can lead to problems such as "next hop racing" and "rebroadcast redundancy." In addition to this, existing routing protocols for MANETs usually take a single routing strategy for all flows. This may lead to inefficient use of resources. In this paper we propose a cross-layer route discovery framework (CRDF to address these problems by exploiting the cross-layer information. CRDF solves the above problems efficiently and enables a new technique: routing strategy automation (RoSAuto. RoSAuto refers to the technique that each source node automatically decides the routing strategy based on the application requirements and each intermediate node further adapts the routing strategy so that the network resource usage can be optimized. To demonstrate the effectiveness and the efficiency of CRDF, we design and evaluate a macrobian route discovery strategy under CRDF.

  15. Encefalitis por virus San Luis en la Ciudad de Buenos Aires durante el brote de dengue 2009

    Directory of Open Access Journals (Sweden)

    Horacio López

    2011-06-01

    Full Text Available Se presenta un paciente de 80 años de edad, residente en la Ciudad de Buenos Aires, con diagnóstico serológico para el virus de la encefalitis de San Luis (SLE durante el brote de dengue ocurrido entre enero y mayo de 2009. Presentaba leucemia linfoide crónica en tratamiento con clorambucilo, cáncer de próstata tratado con hormonoterapia y radioterapia, e imágenes óseas compatibles con metástasis. El estudio del líquido cefalorraquídeo demostró pleocitosis con predominio de mononucleares y proteinorraquia elevada. El resultado de los cultivos para bacterias, hongos y micobacterias, así como el PCR en LCR para herpes virus, HSV, CMV y EBV, fue negativo. Se detectaron anticuerpos IgM para virus SLE tanto en LCR como en muestra de suero, con seroconversión IgG por neutralización en cultivos celulares y resultados negativos para los demás Flavivirus con circulación en Argentina. Se revisan evidencias sobre la presencia de virus de San Luis en nuestro país, y se señala la importancia de la confirmación diagnóstica y el estudio de otros Flavivirus en casos sospechosos de dengue con presentación grave o atípica. Este trabajo remarca la necesidad de fortalecer tanto la vigilancia epidemiológica del virus SLE, como el control vectorial para prevenir las diferentes infecciones transmitidas por mosquitos y conocer su efecto en Salud Pública en la Argentina.

  16. Luis Moya y las bóvedas tabicadas en la posguerra española

    Directory of Open Access Journals (Sweden)

    Adell, Josep Mª

    2005-04-01

    Full Text Available In the precarious economic conditions prevailing after the Spanish Civil War, tiled vault construction was resumed to economize on steel and capitalize on the cheap labour available at the time.
    Luis Moya excelled in this area, re-exploring this construction technique. Moya benefited in this regard from his thorough knowledge of the early twentieth century works of the Guastavinos in New York acquired during his visits to the U.S.A. with Professor Collins.
    His architecture featured tiled vaults with medium-sized spans, normally reinforced with exposed internal Basque tiled arches or ribbing on the extrados.
    He described his architectural experimentation in this field in a book titled "Bóvedas tabicadas" (tile vaults, one of the few extensive treatises on the subject, which surpassed the papers published earlier by Fornés-Gurrea and Bergós.

    Después de la Guerra Civil, y ante la precaria situación económica del pais, se volvió a retomar en España, la construcción tabicada como medio de encomizar acero en la edificación, y aprovechando la mano de obra barata del momento.
    Luis Moya destacó en este aspecto, reinvestigando sobre la construcción tabicada siendo perfectamente conocedor de la obra de los Guastavino en Nueva York, de principios de siglo, por sus visitas realizadas acompañadas del Profesor Collins a EEUU.
    La arquitectura de Moya destacó por aplicar soluciones de bóvedas tabicadas de mediana luz que normalmente reforzaba empleando arcos tabicados internos vistos, o bien acostillando las bóvedas por sus trasdós.
    Esta labor arquitectónica basada en su propia experimentación constructiva, la publicó en el libro "Bóvedas Tabicadas", siendo uno de los pocos tratados amplios sobre este tema existente, superando con él a lo publicado por Fornés-Gurrea y Bergós con anterioridad.

  17. Tecnología lítica y uso diferencial del espacio en Estancia La Suiza, San Luis, Argentina

    OpenAIRE

    Sario, Gisela Mariela

    2017-01-01

    El trabajo pretende contribuir, desde la perspectiva de la organización de la tecnología, al conocimiento de las ocupaciones cazadoras-recolectoras que habitaron las inmediaciones de la Sierra de la Estanzuela, en la provincia de San Luis, Argentina. Se explican cómo fueron las secuencias de producción de herramientas en los sitios de la localidad arqueológica Estancia La Suiza, a partir del análisis de los materiales líticos recuperados en excavación y prospecciones sistemáticas. Las metod...

  18. Prediction and discovery of extremely strong hydrodynamic instabilities due to a velocity jump: theory and experiments

    International Nuclear Information System (INIS)

    Fridman, A M

    2008-01-01

    The theory and the experimental discovery of extremely strong hydrodynamic instabilities are described, viz. the Kelvin-Helmholtz, centrifugal, and superreflection instabilities. The discovery of the last two instabilities was predicted and the Kelvin-Helmholtz instability in real systems was revised by us. (reviews of topical problems)

  19. Discovery of accessible locations using region-based geo-social data

    KAUST Repository

    Wang, Yan; Li, Jianmin; Zhong, Ying; Zhu, Shunzhi; Guo, Danhuai; Shang, Shuo

    2018-01-01

    Geo-social data plays a significant role in location discovery and recommendation. In this light, we propose and study a novel problem of discovering accessible locations in spatial networks using region-based geo-social data. Given a set Q of query

  20. Scaling the walls of discovery: using semantic metadata for integrative problem solving.

    Science.gov (United States)

    Manning, Maurice; Aggarwal, Amit; Gao, Kevin; Tucker-Kellogg, Greg

    2009-03-01

    Current data integration approaches by bioinformaticians frequently involve extracting data from a wide variety of public and private data repositories, each with a unique vocabulary and schema, via scripts. These separate data sets must then be normalized through the tedious and lengthy process of resolving naming differences and collecting information into a single view. Attempts to consolidate such diverse data using data warehouses or federated queries add significant complexity and have shown limitations in flexibility. The alternative of complete semantic integration of data requires a massive, sustained effort in mapping data types and maintaining ontologies. We focused instead on creating a data architecture that leverages semantic mapping of experimental metadata, to support the rapid prototyping of scientific discovery applications with the twin goals of reducing architectural complexity while still leveraging semantic technologies to provide flexibility, efficiency and more fully characterized data relationships. A metadata ontology was developed to describe our discovery process. A metadata repository was then created by mapping metadata from existing data sources into this ontology, generating RDF triples to describe the entities. Finally an interface to the repository was designed which provided not only search and browse capabilities but complex query templates that aggregate data from both RDF and RDBMS sources. We describe how this approach (i) allows scientists to discover and link relevant data across diverse data sources and (ii) provides a platform for development of integrative informatics applications.

  1. Specificity of discoveries in radiochemistry

    International Nuclear Information System (INIS)

    Krivomazov, A.N.

    1977-01-01

    The development of radiochemistry as a science is elucidated. On the basis of original papers and archives materials which have become available only recently, specific features of opening the law of radioactive displacements and isotopy of radioactive elements are presented in detail. A contribution of Hevesy, Russel, Fajans, and Soddy into the solution of this problem is considered; an important role of Rutherford in putting down the priority conflict is shown. Two stages of scientific generalization are singled out in the history of opening the law of radioactive displacements: the stage of the rules and the stage of the laws. On this basis the solutions of the priority problems have been reconsidered. It is shown that the history of radiochemistry is rich in discoveries which have undergone a relatively long evolution

  2. Data Science and Optimal Learning for Material Discovery and Design

    Science.gov (United States)

    ; Optimal Learning for Material Discovery & Design Data Science and Optimal Learning for Material inference and optimization methods that can constrain predictions using insights and results from theory directions in the application of information theoretic tools to materials problems related to learning from

  3. Discovering Steiner Triple Systems through Problem Solving

    Science.gov (United States)

    Sriraman, Bharath

    2004-01-01

    An attempt to implement problem solving as a teacher of ninth grade algebra is described. The problems selected were not general ones, they involved combinations and represented various situations and were more complex which lead to the discovery of Steiner triple systems.

  4. Primeros registros del ibis blanco (Eudocimus albus en el Altiplano de San Luis Potosí, México

    Directory of Open Access Journals (Sweden)

    Natalia de Gortari-Ludlow

    2012-07-01

    Full Text Available Reportamos dos observaciones visuales del ibis blanco (Eudocimus albus de la Laguna de Los Coyotes, un afluente natural del manantial la Media Luna que se localiza en el municipio de Rioverde, San Luis Potosí, México. Los avistamientos ocurrieron en septiembre de 2011 y febrero de 2012. Este es el primer reporte de la presencia de esta ave en dicha localidad, y es importante porque la especie ha sido escasamente encontrada en ambientes no ribereños del Altiplano Mexicano.

  5. 14 CFR 406.143 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Discovery. 406.143 Section 406.143... Transportation Adjudications § 406.143 Discovery. (a) Initiation of discovery. Any party may initiate discovery... after a complaint has been filed. (b) Methods of discovery. The following methods of discovery are...

  6. An overview of aldehyde oxidase: an enzyme of emerging importance in novel drug discovery.

    Science.gov (United States)

    Rashidi, Mohammad-Reza; Soltani, Somaieh

    2017-03-01

    Given the rising trend in medicinal chemistry strategy to reduce cytochrome P450-dependent metabolism, aldehyde oxidase (AOX) has recently gained increased attention in drug discovery programs and the number of drug candidates that are metabolized by AOX is steadily growing. Areas covered: Despite the emerging importance of AOX in drug discovery, there are certain major recognized problems associated with AOX-mediated metabolism of drugs. Intra- and inter-species variations in AOX activity, the lack of reliable and predictive animal models using the common experimental animals, and failure in the predictions of in vivo metabolic activity of AOX using traditional in vitro methods are among these issues that are covered in this article. A comprehensive review of computational human AOX (hAOX) related studies are also provided. Expert opinion: Following the recent progress in the stem cell field, the authors recommend the application of organoids technology as an effective tool to solve the fundamental problems associated with the evaluation of AOX in drug discovery. The recent success in resolving the hAOX crystal structure can too be another valuable data source for the study of AOX-catalyzed metabolism of new drug candidates, using computer-aided drug discovery methods.

  7. Homoparentalidad: explorando el reconocimiento social y los derechos de los homosexuales en la ciudad de San Luis, Argentina

    Directory of Open Access Journals (Sweden)

    Yael guadalupe Calvo Laméndola

    2013-01-01

    Full Text Available Abstract This research paper deals with the opinions of practitioners working in the field of health care, education and law in the city of San Luis on homosexual parenting, and its possible effects in the psychological development of children adopted by homosexual couples. A descriptive-exploratory study was conducted with the aim of making a preliminary approach to this issue, which made it possible to establish the common-sense knowledge referred to above. The sample was composed of 21 individuals, five pediatricians, five lawyers, five teachers and six psychologists. The purpose of this presentation is to communicate the results obtained in one of the four dimensions of the analysis. Said results were obtained before the implementation of the Egalitarian Marriage Act. The results obtained in relation to this dimension reveal that almost all homosexual couples should have the same rights as any other citizen, except that to forming a family by adopting a child. It is important to note that, when answering to the questions; many professionals did not know whether to adhere to the principles of their profession, or to their personal opinion. Resumen El presente artículo de investigación indaga por las opiniones de profesionales del ámbito de la salud, educación y jurídico de la ciudad de San Luis acerca de la homoparentalidad y sus posibles consecuencias en el desarrollo psicológico de niños adoptados por parejas homosexuales. Se realizó un estudio exploratorio de carácter descriptivo, en tanto la finalidad de esta investigación consistía en lograr un primer acercamiento a la problemática en estudio para reconocer el sentido común referido a ella. La muestra quedó finalmente conformada por 21 sujetos: cinco médicos pediatras, cinco abogados, cinco docentes y seis psicólogos. El fin concreto es difundir los resultados obtenidos en una de las cuatro dimensiones de análisis, y fueron recolectados antes de que se promulgara la Ley

  8. Discriminative Motif Discovery via Simulated Evolution and Random Under-Sampling

    OpenAIRE

    Song, Tao; Gu, Hong

    2014-01-01

    Conserved motifs in biological sequences are closely related to their structure and functions. Recently, discriminative motif discovery methods have attracted more and more attention. However, little attention has been devoted to the data imbalance problem, which is one of the main reasons affecting the performance of the discriminative models. In this article, a simulated evolution method is applied to solve the multi-class imbalance problem at the stage of data preprocessing, and at the sta...

  9. Higgs Discovery

    DEFF Research Database (Denmark)

    Sannino, Francesco

    2013-01-01

    has been challenged by the discovery of a not-so-heavy Higgs-like state. I will therefore review the recent discovery \\cite{Foadi:2012bb} that the standard model top-induced radiative corrections naturally reduce the intrinsic non-perturbative mass of the composite Higgs state towards the desired...... via first principle lattice simulations with encouraging results. The new findings show that the recent naive claims made about new strong dynamics at the electroweak scale being disfavoured by the discovery of a not-so-heavy composite Higgs are unwarranted. I will then introduce the more speculative......I discuss the impact of the discovery of a Higgs-like state on composite dynamics starting by critically examining the reasons in favour of either an elementary or composite nature of this state. Accepting the standard model interpretation I re-address the standard model vacuum stability within...

  10. Motivating Communities To Go Beyond the Discovery Plateau

    Science.gov (United States)

    Habermann, T.; Kozimor, J.

    2014-12-01

    Years of emphasizing discovery and minimal metadata requirements have resulted in a culture that accepts that metadata are for discovery and complete metadata are too complex or difficult for researchers to understand and create. Evolving the culture past this "data-discovery plateau" requires a multi-faceted approach that addresses the rational and emotional sides of the problem. On the rational side, scientists know that data and results must be well documented in order to be reproducible, re-usable, and trustworthy. We need tools that script critical moves towards well-described destinations and help identify members of the community that are already leading the way towards those destinations. We need mechanisms that help those leaders share their experiences and examples. On the emotional side, we need to emphasize that high-quality metadata makes data trustworthy, divide the improvement process into digestible pieces and create mechanisms for clearly identifying and rewarding progress. We also need to provide clear opportunities for community members to increase their expertise and to share their skills.

  11. Effects of Problem-Solving, Guided-Discovery and Expository ...

    African Journals Online (AJOL)

    This study investigated the relative effectiveness of problem-solving, guideddiscovery, and expository methods of instruction on students performance in redox reaction, considering their mathematics ability. It was a quasiexperimental research using non-randomized-pre-test post-test control group design with expository ...

  12. [Future status of ischaemic heart disease in the state of San Luis Potosí: A predictive dynamic model].

    Science.gov (United States)

    Gaytán-Hernández, Darío; Díaz-Oviedo, Aracely; Gallegos-García, Verónica; Terán-Figueroa, Yolanda

    To develop a predictive dynamic model to generate and analyse the future status of the incidence rate of ischaemic heart disease in a population of 25 years and over in Mexico, according to the variation in time of some risk factors. Retrospective ecological study performed during the period 2013-2015, in San Luis Potosí City, Mexico. Secondary databases that corresponded to the years 2000, 2005, and 2010, were used along with official indicators of the 58 municipalities of the state of San Luis Potosí. Eight indicators were analysed at municipality level, using principal components analysis, structural equation modelling, dynamic modelling, and simulation software methods. Three components were extracted, which together explained 80.43% of the total variance of the official indicators used. The second component had a weight of 16.36 units that favoured an increase of the disease analysed. This component was integrated only by the indicator AGE 60-64 and the expected stage of it increasing. The structural model confirmed that the indicators explain 42% of the variation of this disease. The possible stages for the years 2015, 2020, and 2025 are 195.7, 240.7, and 298.0, respectively for every 100,000 inhabitants aged 25 and over. An exponential increase in the incidence rate of ischaemic heart disease is expected, with the age of 60-64 years being identified as the highest risk factor. Copyright © 2017 Instituto Nacional de Cardiología Ignacio Chávez. Publicado por Masson Doyma México S.A. All rights reserved.

  13. Discovery and Selection of Semantic Web Services

    CERN Document Server

    Wang, Xia

    2013-01-01

    For advanced web search engines to be able not only to search for semantically related information dispersed over different web pages, but also for semantic services providing certain functionalities, discovering semantic services is the key issue. Addressing four problems of current solution, this book presents the following contributions. A novel service model independent of semantic service description models is proposed, which clearly defines all elements necessary for service discovery and selection. It takes service selection as its gist and improves efficiency. Corresponding selection algorithms and their implementation as components of the extended Semantically Enabled Service-oriented Architecture in the Web Service Modeling Environment are detailed. Many applications of semantic web services, e.g. discovery, composition and mediation, can benefit from a general approach for building application ontologies. With application ontologies thus built, services are discovered in the same way as with single...

  14. Lost in translation? Role of metabolomics in solving translational problems in drug discovery and development

    NARCIS (Netherlands)

    Greef, J. van der; Adourian, A.; Muntendam, P.; McBurney, R.N.

    2006-01-01

    Too few drug discovery projects generate a marketed drug product, often because preclinical studies fail to predict the clinical experience with a drug candidate. Improving the success of preclinical-to-clinical translation is of paramount importance in optimizing the pharmaceutical value chain.

  15. Mineralogy of auriferous deposits of the quaternary deposits in the San Luis Province, Argentina

    International Nuclear Information System (INIS)

    Karlsson, A.; Ayala, R. . E mail: Karlsson@arnet.com.ar

    2004-01-01

    The objective of this work is to study the mineralogy of the sands and clays of the quaternary deposits in the San Luis Mountain, Argentina. A series of algorithms applied to the sand fraction has permitted to determine sedimentary discontinuities. The two micron fraction of the sediments has been studied by a quantification technique based on X-ray diffraction by means of oriented preparations and run with copper tube. These quaternary silts have received fluvial lateral contributions. The high cristalinidad of non expandibles and fireclay clay show the antique of the silts. The polygenic processes have generated a great variety of clay mineral species like a large quantities of illite and in lesser extend kaolinite and smectites. The illite was probably generated by diagenetic changes. The high cristalinidad of non expandibles and fireclay clay show the antique of the silts [es

  16. El basamento de la sierra de San Luis: Nuevas evidencias magnéticas y sus implicancias tectónicas

    OpenAIRE

    CJ Chernicoff; VA Ramos

    2003-01-01

    Los mapas aeromagnéticos disponibles de las sierras de San Luis y Comechingones en el sector sudoriental de las Sierras Pampeanas de Argentina, permiten examinar las características geológicas y estructurales de las unidades metamórficas e intrusivas del basamento de la región. A través de la aplicación del filtro de continuación ascendente a los datos del campo magnético total reducido al polo, se ha podido observar la configuración profunda de las distintas unidades. Entre ellas se destaca ...

  17. La comunicación no verbal en la proyección mediática de la imagen política de José Luis Rodríguez Zapatero durante el curso político 2006-2007

    OpenAIRE

    Hernández Herrarte, María

    2011-01-01

    Esta tesis doctoral pretende realizar una descripción de los comportamientos no verbales más representativos del actual presidente del Gobierno, José Luis Rodríguez Zapatero, con el objeto de indagar en la construcción y transmisión de su liderazgo político. Asimismo, una vez trazado el perfil no verbal de José Luis Rodríguez Zapatero (centrado en el análisis del comportamiento kinésico y el aspecto físico y la apariencia), se intentará constatar si esa comunicación no verbal que despliega es...

  18. The discovery of the periodic table as a case of simultaneous discovery.

    Science.gov (United States)

    Scerri, Eric

    2015-03-13

    The article examines the question of priority and simultaneous discovery in the context of the discovery of the periodic system. It is argued that rather than being anomalous, simultaneous discovery is the rule. Moreover, I argue that the discovery of the periodic system by at least six authors in over a period of 7 years represents one of the best examples of a multiple discovery. This notion is supported by a new view of the evolutionary development of science through a mechanism that is dubbed Sci-Gaia by analogy with Lovelock's Gaia hypothesis. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  19. Beyond Discovery

    DEFF Research Database (Denmark)

    Korsgaard, Steffen; Sassmannshausen, Sean Patrick

    2017-01-01

    In this chapter we explore four alternatives to the dominant discovery view of entrepreneurship; the development view, the construction view, the evolutionary view, and the Neo-Austrian view. We outline the main critique points of the discovery presented in these four alternatives, as well...

  20. The pastoral implications of human freedom according to Juan Luis Segundo

    Directory of Open Access Journals (Sweden)

    Vicente de Paula Ferreira

    2016-09-01

    Full Text Available The paper aims to reflect the issue of human freedom based on the underlying principles of the Christian faith in a time of anthropological vulnerability, especially in Latin American. It holds that Christianity must insist on its proposal to promote universal goodwill, despite a human horizon marked by selfishness and lust for power and money. This approach presupposes a radical position of a listener of the divine mystery, revealed in Jesus Christ, as a way to fulfill the human condition. Theoretical framework: Liberation Theology, in the view of Juan Luis Segundo, and its well-established tradition of transforming realities of injustice through faith, comprises the core argument of this text. Findings: Christian salvation necessarily implies the kenosis (κένωσις of Jesus, i.e., Christ “emptied Himself” (Ph. 2:7, and through His humble dispossession, He broke with all closed systems of the world, and inaugurated a new venture of a liberated freedom: the agape of love. Conclusion: Christian praxis as daily care for the poorest and prophecy of forgiveness rescues the memory of the victims of all forms of human selfishness. 

  1. "Eureka, Eureka!" Discoveries in Science

    Science.gov (United States)

    Agarwal, Pankaj

    2011-01-01

    Accidental discoveries have been of significant value in the progress of science. Although accidental discoveries are more common in pharmacology and chemistry, other branches of science have also benefited from such discoveries. While most discoveries are the result of persistent research, famous accidental discoveries provide a fascinating…

  2. [Physical factors influencing the floristic relationships of pinyon pine (Pinaceae) from San Luis Potosi, Mexico].

    Science.gov (United States)

    Romero, Angélica; Luna, Mario; García, Edmundo

    2014-06-01

    In plant communities, the species distribution patterns and their relationships with environmental factors are of central importance in ecology. In San Luis Potosí of Mexico, woodlands of Pinus cembroides and P. johannis are sympatric, but P. cembroides tends to be located in South and Southwest slopes, in more disturbed sites; unlike, P. johannis, is mostly distributed in mesic areas, in North and Northeast slopes. The aim of this study was to analyze the influence of some physical factors on the floristic similarity of pinyon pine P. cembroides and P. johannis. The study area was located in the Sierra San Miguelito, San Luis Potosí, Mexico. We selected 40 sampling units spread over an area of 50km2. In each unit, we laid out two 20m long lines perpendicular to each other, in which we recorded cover data of the plant species intercepted. We developed two data matrices, the first one including cover values of 91 species, and the second one, considering seven topographical, climatic, and solar radiation variables. We applied cluster analysis and ordination to explore the influence of environmental variables on the floristic differentiation of pinyon pine woodlands. Clustering showed six groups, the first three characterized by P. cembroides. The ordination showed that variance represented by the first three axes was 65.9%. Axis 1 was positively correlated with altitude and negatively with mean annual temperature; axes two and three, showed low correlation with the variables tested. P. cembroides woodlands and accompanying flora tend to be located in lower altitude, higher mean annual temperature, and mainly in South-Southwestern slopes. In contrast, stands of P. johannis, mixed stands of P. johannis-P. cembroides, and Quercus potosina, were usually founded in greater altitudes, mean annual temperature slightly lower, and North-Northeastern exposure. The sites of these monospecific and mixed woodlands with associated species, indicators of environmental variables

  3. 30 CFR 44.24 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Discovery. 44.24 Section 44.24 Mineral... Discovery. Parties shall be governed in their conduct of discovery by appropriate provisions of the Federal... discovery. Alternative periods of time for discovery may be prescribed by the presiding administrative law...

  4. 19 CFR 356.20 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Discovery. 356.20 Section 356.20 Customs Duties... § 356.20 Discovery. (a) Voluntary discovery. All parties are encouraged to engage in voluntary discovery... sanctions proceeding. (b) Limitations on discovery. The administrative law judge shall place such limits...

  5. Chemical Discovery

    Science.gov (United States)

    Brown, Herbert C.

    1974-01-01

    The role of discovery in the advance of the science of chemistry and the factors that are currently operating to handicap that function are considered. Examples are drawn from the author's work with boranes. The thesis that exploratory research and discovery should be encouraged is stressed. (DT)

  6. Knowledge-Based Topic Model for Unsupervised Object Discovery and Localization.

    Science.gov (United States)

    Niu, Zhenxing; Hua, Gang; Wang, Le; Gao, Xinbo

    Unsupervised object discovery and localization is to discover some dominant object classes and localize all of object instances from a given image collection without any supervision. Previous work has attempted to tackle this problem with vanilla topic models, such as latent Dirichlet allocation (LDA). However, in those methods no prior knowledge for the given image collection is exploited to facilitate object discovery. On the other hand, the topic models used in those methods suffer from the topic coherence issue-some inferred topics do not have clear meaning, which limits the final performance of object discovery. In this paper, prior knowledge in terms of the so-called must-links are exploited from Web images on the Internet. Furthermore, a novel knowledge-based topic model, called LDA with mixture of Dirichlet trees, is proposed to incorporate the must-links into topic modeling for object discovery. In particular, to better deal with the polysemy phenomenon of visual words, the must-link is re-defined as that one must-link only constrains one or some topic(s) instead of all topics, which leads to significantly improved topic coherence. Moreover, the must-links are built and grouped with respect to specific object classes, thus the must-links in our approach are semantic-specific , which allows to more efficiently exploit discriminative prior knowledge from Web images. Extensive experiments validated the efficiency of our proposed approach on several data sets. It is shown that our method significantly improves topic coherence and outperforms the unsupervised methods for object discovery and localization. In addition, compared with discriminative methods, the naturally existing object classes in the given image collection can be subtly discovered, which makes our approach well suited for realistic applications of unsupervised object discovery.Unsupervised object discovery and localization is to discover some dominant object classes and localize all of object

  7. Analysis of José Luis Rodríguez Zapatero’s nonverbal communication

    Directory of Open Access Journals (Sweden)

    Imelda Rodríguez-Escanciano, Ph.D.

    2010-01-01

    Full Text Available Aware of television’s high level of persuasion and impact, politicians have progressively adapted their messages to the guidelines of the audiovisual media in order to strongly persuade TV viewers, which are seen as potential voters. Currently, the communication, marketing and telegenicity teams of most political parties do not only train their politicians to effectively use verbal communication, but they also try to reinforce their non-verbal communications skills, because they understand that a really effective message is only created through the correct combination of both dimensions. This article presents an in-depth study of the nonverbal communication displayed by the Prime Minister of Spain, José Luis Rodríguez Zapatero, during the first quarter of 2010 when a political topic predominated in the agenda: the financial crisis. Through content analysis, and a self-developed methodology, the study aims to decipher the strategic meaning of this political leader’s kinesic behaviour in the second edition of Telediario, the news programme broadcast by Spain’s Public TV Network (Televisión Española, aka, TVE.

  8. 24 CFR 180.500 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discovery. 180.500 Section 180.500... OPPORTUNITY CONSOLIDATED HUD HEARING PROCEDURES FOR CIVIL RIGHTS MATTERS Discovery § 180.500 Discovery. (a) In general. This subpart governs discovery in aid of administrative proceedings under this part. Discovery in...

  9. 22 CFR 224.21 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discovery. 224.21 Section 224.21 Foreign....21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of... parties, discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery...

  10. La cofradía de la Santa Veracruz y los planos arquitectónicos más antiguos de San Luis Potosí: Un ejemplo del corporativismo novohispano a través de la arquitectura

    OpenAIRE

    Hernández Soubervielle, Armando

    2014-01-01

    El presente artículo discurre por tres ejes fundamentales. El primero de ellos es aportar información obtenida de fuentes primarias, referente a la cofradía de la Santa Veracruz de San Luis Potosí, lo que sirve para dar a conocer y analizar por primera vez los planos arquitectónicos más antiguos (1620) de San Luis Potosí, mismos que hasta ahora estaban inéditos. A la luz de estos planos y su interpretación, se mostrará su relación con el tratado de arquitectura de Sebastián Serlio y de cómo e...

  11. Geology and petrography of basement in south extreme in Sierra Grande de San Luis, Argentina

    International Nuclear Information System (INIS)

    Morosini, A.; Ortiz Suarez, A.

    2007-01-01

    In the south of the Sierra de San Luis is recognized a basement composed by La Escalerilla and Los Puquios granites, accompanied by schist, mylonite s and mafic-ultramafic rocks. The schists, La Escalerilla granite and the mafic -ultramafic rocks are affected by a regional metamorphism in anphibolites facies, the two first present a N-S foliation di ping to east. The mylonite s correspond to a second event of deformation, distributed in thin belts of NNE-SSO direction and inclination to east, developed in green schist to anphibolites facies. Los Puquios granite represents the more young of the basement rocks and the intrusion was associated with a shear zone. Los Puquios granite forms dikes and small plutons cutting La Escalerilla granite and micas chits in high cortical levels

  12. La reescritura de La infancia en Los días ocultos de Luis Oyarzún

    Directory of Open Access Journals (Sweden)

    Lorena Amaro Castro

    2013-12-01

    Full Text Available El filósofo Luis Oyarzún escribió dos novelas de carácter autobiográfico en que presenta las percepciones de un niño de provincia: La infancia (1940 y Los días ocultos (1955. Críticos como Roberto Hozven, Leonidas Morales y Olga Grau manifiestan que la segunda es una reelaboración de la primera. El siguiente artículo desarrolla una comparación entre ambos textos, buscando dilucidar y comprender cuáles son las diferencias entre ellos y en qué medida revelan una maduración en la escritura e inquietudes de un autor que ocupa un lugar hasta ahora marginal en la construcción canónica filosófica y literaria chilena.

  13. 19 CFR 207.109 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Discovery. 207.109 Section 207.109 Customs Duties... and Committee Proceedings § 207.109 Discovery. (a) Discovery methods. All parties may obtain discovery under such terms and limitations as the administrative law judge may order. Discovery may be by one or...

  14. 15 CFR 25.21 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Discovery. 25.21 Section 25.21... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for..., discovery is available only as ordered by the ALJ. The ALJ shall regulate the timing of discovery. (d...

  15. Autour des “scénographies auctoriales” : entretien avec José-Luis Diaz, auteur de L’écrivain imaginaire (2007 “Authorial scenographies”: an interview with José-Luis Diaz, author of L’écrivain imaginaire (2007

    Directory of Open Access Journals (Sweden)

    Dominique Maingueneau

    2009-10-01

    Full Text Available José-Luis, selon ta propre formulation, ton livre L’écrivain imaginaire s’insère dans une histoire des représentations de l’écrivain. Pourrais-tu nous en dire plus sur les tenants et les aboutissants de ce projet ? En particulier, dans quel sens prends-tu l’expression « écrivain imaginaire », à distinguer de la personne réelle de l’écrivain ?Au début de mes recherches, à l’heure où l’auteur était censé être mort selon le titre célèbre d’un article de Roland Barthes (1968, j’ai pensé d’emblée...

  16. The future workforce in cancer prevention: advancing discovery, research, and technology.

    Science.gov (United States)

    Newhauser, Wayne D; Scheurer, Michael E; Faupel-Badger, Jessica M; Clague, Jessica; Weitzel, Jeffrey; Woods, Kendra V

    2012-05-01

    As part of a 2-day conference on October 15 and 16, 2009, a nine-member task force composed of scientists, clinicians, educators, administrators, and students from across the USA was formed to discuss research, discovery, and technology obstacles to progress in cancer prevention and control, specifically those related to the cancer prevention workforce. This article summarizes the task force's findings on the current state of the cancer prevention workforce in this area and its needs for the future. The task force identified two types of barriers impeding the current cancer prevention workforce in research, discovery, and technology from reaching its fullest potential: (1) limited cross-disciplinary research opportunities with underutilization of some disciplines is hampering discovery and research in cancer prevention, and (2) new research avenues are not being investigated because technology development and implementation are lagging. Examples of impediments and desired outcomes are provided in each of these areas. Recommended solutions to these problems are based on the goals of enhancing the current cancer prevention workforce and accelerating the pace of discovery and clinical translation.

  17. 39 CFR 963.14 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Discovery. 963.14 Section 963.14 Postal Service... PANDERING ADVERTISEMENTS STATUTE, 39 U.S.C. 3008 § 963.14 Discovery. Discovery is to be conducted on a... such discovery as he or she deems reasonable and necessary. Discovery may include one or more of the...

  18. Neptune's Discovery: Le Verrier, Adams, and the Assignment of Credit

    Science.gov (United States)

    Sheehan, William

    2011-01-01

    As one of the most significant achievements of 19th century astronomy, the discovery of Neptune has been the subject of a vast literature. A large part of this literature--beginning with the period immediately after the optical discovery in Berlin--has been the obsession with assigning credit to the two men who attempted to calculate the planet's position (and initially this played out against the international rivalry between France and England). Le Verrier and Adams occupied much different positions in the Scientific Establishments of their respective countries; had markedly different personalities; and approached the investigation using different methods. A psychiatrist and historian of astronomy tries to provide some new contexts to the familiar story of the discovery of Neptune, and argues that the personalities of these two men played crucial roles in their approaches to the problem they set themselves and the way others reacted to their stimuli. Adams had features of high-functioning autism, while Le Verrier's domineering, obsessive, orderly personality--though it allowed him to be immensely productive--eventually led to serious difficulties with his peers (and an outright revolt). Though it took extraordinary smarts to calculate the position of Neptune, the discovery required social skills that these men lacked--and thus the process to discovery was more bumbling and adventitious than it might have been. The discovery of Neptune occurred at a moment when astronomy was changing from that of heroic individuals to team collaborations involving multiple experts, and remains an object lesson in the sociological aspects of scientific endeavor.

  19. Swordmanship as Mathematical Science: The Curious Case of Luis Pacheco de Narváez

    Directory of Open Access Journals (Sweden)

    Felix Kurt Ernst Schmelzer

    2016-11-01

    Full Text Available From the 15th century on, the practitioners of the mechanical arts obtain a new self-confidence and do no longer want to be regarded merely as manual workers. In this context, they frequently underline the mathematical basis of their discipline in order to increase its value from the status of a mechanical to that of a liberal art. In the Spanish golden age period, the military art, amongst others, is conceived as a mathematical discipline. A particularly curious case is the Libro de las grandezas de la espada (1600 whose author, Luis Pacheco de Narváez (1570-1640, propagates the art of swordsmanship, which he names «the true skill», as a science based on the disciplines of the quadrivium. The present article outlines the arguments applied by Pacheco in a preliminary chapter in order to prove the mathematical and scientific status of his discipline.

  20. A Microgenetic Study of Insightful Problem Solving

    Science.gov (United States)

    Luwel, Koen; Siegler, Robert S.; Verschaffel, Lieven

    2008-01-01

    An eight-session microgenetic study of acquisition of an insightful problem-solving strategy was conducted. A total of 35 second graders who did not use this insightful strategy initially were assigned to two groups that differed in the frequency of problems likely to facilitate discovery and generalization of the strategy. Children in the…

  1. Escuela pública digital en pueblos originarios. La propuesta de la Universidad de la Punta para las comunidades Ranquel y Huarpe de la provincia de San Luis. Argentina

    Directory of Open Access Journals (Sweden)

    Silvia Baldivieso

    2014-01-01

    Full Text Available El artículo describe y analiza la propuesta de formación escolar que ofrece, actualmente, la Universidad de La Punta a comunidades originarias de la Provincia de San Luis, Argentina, en el marco del proyecto de Escuelas Públicas Digitales.La propuesta gubernamental de desarrollar acciones educativas orientadas al logro de una “Educación de Calidad para Todos”, articulada al trabajo, también gubernamental, de rescate de la memoria y la cultura de los pueblos pre existentes en el territorio de San Luis, ha dado lugar al desarrollo de un modelo de organización y gestión educativa y curricular particular, de enseñanza personalizada y aprendizaje autorregulado basado en las tecnologías de la información y la comunicación. Dicha organización, destinada a las comunidades originarias, abre sus puertas a otros habitantes del pueblo sanluiseño y atiende necesidades educativas de niños, jóvenes y adultos.

  2. Usability of Discovery Portals

    OpenAIRE

    Bulens, J.D.; Vullings, L.A.E.; Houtkamp, J.M.; Vanmeulebrouk, B.

    2013-01-01

    As INSPIRE progresses to be implemented in the EU, many new discovery portals are built to facilitate finding spatial data. Currently the structure of the discovery portals is determined by the way spatial data experts like to work. However, we argue that the main target group for discovery portals are not spatial data experts but professionals with limited spatial knowledge, and a focus outside the spatial domain. An exploratory usability experiment was carried out in which three discovery p...

  3. Urgencias neuroquirúrgicas en el Instituto Superior de Medicina Militar "Luis Díaz Soto": Estudio de cinco años

    OpenAIRE

    Felipe Morán, Armando; Quintanal Cordero, Nelson; Tápanes Domínguez, Alejandro; Pérez La O, Pablo; Fuentes Rodríguez, Nelson; Fuertes Vicente, Dania

    2006-01-01

    Se realizó un estudio prospectivo, descriptivo y longitudinal de la conducta neuroquirúrgica seguida con todos los pacientes atendidos desde enero de 1998 hasta diciembre de 2002 en el Cuerpo de Guardia del Instituto Superior de Medicina Militar “Dr. Luis Díaz Soto”. Los datos se obtuvieron en las entregas de guardia, registros médicos, historias clínicas, libro de control de intervenciones quirúrgicas y de ingresos. En total se atendieron 8 113 pacientes, de ellos el 17 % correspondió a niño...

  4. Luis de León (1527-1591 y su teoría de la justicia: aspectos principales de su doctrina

    Directory of Open Access Journals (Sweden)

    Sebastián Contreras

    2014-04-01

    Full Text Available Las investigaciones sobre Luis de León se han centrado, sobre todo, en su mística, narrativa y teoría literaria. En este trabajo, el autor intenta desarrollar los principales aspectos de su teoría jurídica. Al igual que otros grandes teólogos de la Escuela de Salamanca, también León ha estudiado el problema de la naturaleza de la ley humana y su vinculación con el derecho natural. Éste es, justamente, el tema del siguiente trabajo.

  5. What’s in a word? : Rethinking facet headings in a discovery service

    Directory of Open Access Journals (Sweden)

    David Nelson

    2015-06-01

    Full Text Available The emergence of Discovery systems has been well received by libraries who have long been concerned with offering a smorgasbord of databases that require either individual searching of databases or the problematic use of federated searching.  The ability to search across a wide array of subscribed and open-access information resources via a centralized index has opened up access for users to a library’s wealth of information resources.  This capability has been particularly praised for its ‘google like’ search interface, thereby conforming to user expectations for information searching.  Yet, all discovery services also include facets as a search capability and thus provide faceted navigation which is a search feature that Google is not particularly well suited for.  Discovery services thus provide a hybrid search interface.  An examination of e-commerce sites clearly shows that faceted navigation is an integral part of their discovery systems.  Many library OPACs also now are being developed with faceted navigation capabilities.  However, the discovery services faceted structures suffer from a number of problems which inhibit their usefulness and their potential.  This article examines a number of these issues and it offers suggestions for improving the discovery search interface.  It also argues that vendors and libraries need to work together to more closely analyze the user experience of the discovery system.

  6. Distribution and abundance of Least Bell’s Vireos (Vireo bellii pusillus) and Southwestern Willow Flycatchers (Empidonax traillii extimus) on the Middle San Luis Rey River, San Diego, southern California—2016 data summary

    Science.gov (United States)

    Allen, Lisa D.; Howell, Scarlett L.; Kus, Barbara E.

    2017-09-29

    Executive SummaryWe surveyed for Least Bell’s Vireos (LBVI) (Vireo bellii pusillus) and Southwestern Willow Flycatchers (SWFL) (Empidonax traillii extimus) along the San Luis Rey River, between College Boulevard in Oceanside and Interstate 15 in Fallbrook, California (middle San Luis Rey River), in 2016. Surveys were done from March 30 to July 11 (LBVI) and from May 18 to July 30 (SWFL). We found 142 LBVI territories, at least 106 of which were occupied by pairs. Six additional transient LBVIs were detected. Of 20 banded LBVIs detected in the survey area, 9 had been given full color-band combinations prior to 2016, although we were unable to determine the exact color combination of 1 female LBVI. Seven other LBVIs with single (natal) federal bands were recaptured and banded in 2016. Four vireos with single dark blue federal bands indicating that they were banded as nestlings on the lower San Luis Rey River could not be recaptured for identification.Three SFWL territories were observed in the survey area in 2016. Two territories were occupied by pairs and one by a male of unknown breeding status. Both pairs attempted to nest at least once, and both pairs were successful, fledging three young each. Nesting began in early June and continued into July. Brown-Headed Cowbird (Molothrus ater) eggs were not observed in either nest. An additional 12 transient Willow Flycatchers of unknown subspecies were detected in 2016.Two of the five resident SWFLs were originally banded as nestlings on Marine Corps Base Camp Pendleton. One male and one female were banded as nestlings on Camp Pendleton in 2009 and 2011, respectively. One natal male of unknown breeding status, originally banded as a nestling on the middle San Luis Rey River in 2015, was recaptured and given a unique color combination in 2016. This male was later detected on Marine Corps Base Camp Pendleton.

  7. Association between Urine Fluoride and Dental Fluorosis as a Toxicity Factor in a Rural Community in the State of San Luis Potosi

    OpenAIRE

    Jarquín-Yañez, Lizet; Mejía-Saavedra, José de Jesús; Molina-Frechero, Nelly; Gaona, Enrique; Rocha-Amador, Diana Olivia; López-Guzmán, Olga Dania; Bologna-Molina, Ronell

    2015-01-01

    Objective. The aim of this study is to investigate urine fluoride concentration as a toxicity factor in a rural community in the state of San Luis Potosi, Mexico. Materials and Methods. A sample of 111 children exposed to high concentrations of fluoride in drinking water (4.13?mg/L) was evaluated. Fluoride exposure was determined by measuring urine fluoride concentration using the potentiometric method with an ion selective electrode. The diagnosis of dental fluorosis was performed by clinica...

  8. The incidence of essential competences and the owner-director on strong growth of a manufacturing SMEs in San Luis Potosí, Mexico

    OpenAIRE

    Molina Sánchez, Rubén

    2009-01-01

    This article is intended to analyse a group of manufacturing SMEs in San Luis Potosí, Mexico, in order to explain the characteristics which bring about their high level of growth. The context was therefore adapted to a research model sponsored by OECD, which gives pride of place to qualitative methods, well-founded theory and the use of software to analyse information given by interviewees. Categories of perception of innovation were identified (that is, control of information, essential comp...

  9. 19 CFR 354.10 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 19 Customs Duties 3 2010-04-01 2010-04-01 false Discovery. 354.10 Section 354.10 Customs Duties... ANTIDUMPING OR COUNTERVAILING DUTY ADMINISTRATIVE PROTECTIVE ORDER § 354.10 Discovery. (a) Voluntary discovery. All parties are encouraged to engage in voluntary discovery procedures regarding any matter, not...

  10. 36 CFR 1150.63 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Discovery. 1150.63 Section... PRACTICE AND PROCEDURES FOR COMPLIANCE HEARINGS Prehearing Conferences and Discovery § 1150.63 Discovery. (a) Parties are encouraged to engage in voluntary discovery procedures. For good cause shown under...

  11. 37 CFR 11.52 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Discovery. 11.52 Section 11... Disciplinary Proceedings; Jurisdiction, Sanctions, Investigations, and Proceedings § 11.52 Discovery. Discovery... establishes that discovery is reasonable and relevant, the hearing officer, under such conditions as he or she...

  12. Usability of Discovery Portals

    NARCIS (Netherlands)

    Bulens, J.D.; Vullings, L.A.E.; Houtkamp, J.M.; Vanmeulebrouk, B.

    2013-01-01

    As INSPIRE progresses to be implemented in the EU, many new discovery portals are built to facilitate finding spatial data. Currently the structure of the discovery portals is determined by the way spatial data experts like to work. However, we argue that the main target group for discovery portals

  13. 14 CFR 16.213 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Discovery. 16.213 Section 16.213... PRACTICE FOR FEDERALLY-ASSISTED AIRPORT ENFORCEMENT PROCEEDINGS Hearings § 16.213 Discovery. (a) Discovery... discovery permitted by this section if a party shows that— (1) The information requested is cumulative or...

  14. 28 CFR 76.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Discovery. 76.21 Section 76.21 Judicial... POSSESSION OF CERTAIN CONTROLLED SUBSTANCES § 76.21 Discovery. (a) Scope. Discovery under this part covers... as a general guide for discovery practices in proceedings before the Judge. However, unless otherwise...

  15. 40 CFR 27.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Discovery. 27.21 Section 27.21... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for..., discovery is available only as ordered by the presiding officer. The presiding officer shall regulate the...

  16. 37 CFR 41.150 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Discovery. 41.150 Section 41... COMMERCE PRACTICE BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES Contested Cases § 41.150 Discovery. (a) Limited discovery. A party is not entitled to discovery except as authorized in this subpart. The...

  17. 14 CFR 13.220 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Discovery. 13.220 Section 13.220... INVESTIGATIVE AND ENFORCEMENT PROCEDURES Rules of Practice in FAA Civil Penalty Actions § 13.220 Discovery. (a) Initiation of discovery. Any party may initiate discovery described in this section, without the consent or...

  18. 49 CFR 604.38 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 7 2010-10-01 2010-10-01 false Discovery. 604.38 Section 604.38 Transportation... TRANSPORTATION CHARTER SERVICE Hearings. § 604.38 Discovery. (a) Permissible forms of discovery shall be within the discretion of the PO. (b) The PO shall limit the frequency and extent of discovery permitted by...

  19. 15 CFR 719.10 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Discovery. 719.10 Section 719.10... Discovery. (a) General. The parties are encouraged to engage in voluntary discovery regarding any matter... the Federal Rules of Civil Procedure relating to discovery apply to the extent consistent with this...

  20. 24 CFR 26.18 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discovery. 26.18 Section 26.18... PROCEDURES Hearings Before Hearing Officers Discovery § 26.18 Discovery. (a) General. The parties are encouraged to engage in voluntary discovery procedures, which may commence at any time after an answer has...

  1. 42 CFR 426.532 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Discovery. 426.532 Section 426.532 Public Health... § 426.532 Discovery. (a) General rule. If the Board orders discovery, the Board must establish a reasonable timeframe for discovery. (b) Protective order—(1) Request for a protective order. Any party...

  2. 49 CFR 1503.633 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Discovery. 1503.633 Section 1503.633... Rules of Practice in TSA Civil Penalty Actions § 1503.633 Discovery. (a) Initiation of discovery. Any party may initiate discovery described in this section, without the consent or approval of the ALJ, at...

  3. 14 CFR 1264.120 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Discovery. 1264.120 Section 1264.120... PENALTIES ACT OF 1986 § 1264.120 Discovery. (a) The following types of discovery are authorized: (1..., discovery is available only as ordered by the presiding officer. The presiding officer shall regulate the...

  4. 22 CFR 128.6 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discovery. 128.6 Section 128.6 Foreign... Discovery. (a) Discovery by the respondent. The respondent, through the Administrative Law Judge, may... discovery if the interests of national security or foreign policy so require, or if necessary to comply with...

  5. 24 CFR 26.42 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Discovery. 26.42 Section 26.42... PROCEDURES Hearings Pursuant to the Administrative Procedure Act Discovery § 26.42 Discovery. (a) General. The parties are encouraged to engage in voluntary discovery procedures, which may commence at any time...

  6. 49 CFR 386.37 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Discovery. 386.37 Section 386.37 Transportation... and Hearings § 386.37 Discovery. (a) Parties may obtain discovery by one or more of the following...; and requests for admission. (b) Discovery may not commence until the matter is pending before the...

  7. 29 CFR 1955.32 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Discovery. 1955.32 Section 1955.32 Labor Regulations...) PROCEDURES FOR WITHDRAWAL OF APPROVAL OF STATE PLANS Preliminary Conference and Discovery § 1955.32 Discovery... allow discovery by any other appropriate procedure, such as by interrogatories upon a party or request...

  8. 42 CFR 426.432 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Discovery. 426.432 Section 426.432 Public Health... § 426.432 Discovery. (a) General rule. If the ALJ orders discovery, the ALJ must establish a reasonable timeframe for discovery. (b) Protective order—(1) Request for a protective order. Any party receiving a...

  9. 10 CFR 13.21 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Discovery. 13.21 Section 13.21 Energy NUCLEAR REGULATORY COMMISSION PROGRAM FRAUD CIVIL REMEDIES § 13.21 Discovery. (a) The following types of discovery are...) Unless mutually agreed to by the parties, discovery is available only as ordered by the ALJ. The ALJ...

  10. 49 CFR 1121.2 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 8 2010-10-01 2010-10-01 false Discovery. 1121.2 Section 1121.2 Transportation... TRANSPORTATION RULES OF PRACTICE RAIL EXEMPTION PROCEDURES § 1121.2 Discovery. Discovery shall follow the procedures set forth at 49 CFR part 1114, subpart B. Discovery may begin upon the filing of the petition for...

  11. 38 CFR 42.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Discovery. 42.21 Section... IMPLEMENTING THE PROGRAM FRAUD CIVIL REMEDIES ACT § 42.21 Discovery. (a) The following types of discovery are... creation of a document. (c) Unless mutually agreed to by the parties, discovery is available only as...

  12. 22 CFR 521.21 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Discovery. 521.21 Section 521.21 Foreign... Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for... interpreted to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

  13. 31 CFR 10.71 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Discovery. 10.71 Section 10.71 Money... SERVICE Rules Applicable to Disciplinary Proceedings § 10.71 Discovery. (a) In general. Discovery may be... relevance, materiality and reasonableness of the requested discovery and subject to the requirements of § 10...

  14. 39 CFR 955.15 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 39 Postal Service 1 2010-07-01 2010-07-01 false Discovery. 955.15 Section 955.15 Postal Service... APPEALS § 955.15 Discovery. (a) The parties are encouraged to engage in voluntary discovery procedures. In connection with any deposition or other discovery procedure, the Board may issue any order which justice...

  15. 43 CFR 35.21 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Discovery. 35.21 Section 35.21 Public... AND STATEMENTS § 35.21 Discovery. (a) The following types of discovery are authorized: (1) Requests...) Unless mutually agreed to by the parties, discovery is available only as ordered by the ALJ. The ALJ...

  16. 15 CFR 766.9 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Discovery. 766.9 Section 766.9... PROCEEDINGS § 766.9 Discovery. (a) General. The parties are encouraged to engage in voluntary discovery... provisions of the Federal Rules of Civil Procedure relating to discovery apply to the extent consistent with...

  17. Knowledge Discovery and Data Mining in Iran's Climatic Researches

    Science.gov (United States)

    Karimi, Mostafa

    2013-04-01

    Advances in measurement technology and data collection is the database gets larger. Large databases require powerful tools for analysis data. Iterative process of acquiring knowledge from information obtained from data processing is done in various forms in all scientific fields. However, when the data volume large, and many of the problems the Traditional methods cannot respond. in the recent years, use of databases in various scientific fields, especially atmospheric databases in climatology expanded. in addition, increases in the amount of data generated by the climate models is a challenge for analysis of it for extraction of hidden pattern and knowledge. The approach to this problem has been made in recent years uses the process of knowledge discovery and data mining techniques with the use of the concepts of machine learning, artificial intelligence and expert (professional) systems is overall performance. Data manning is analytically process for manning in massive volume data. The ultimate goal of data mining is access to information and finally knowledge. climatology is a part of science that uses variety and massive volume data. Goal of the climate data manning is Achieve to information from variety and massive atmospheric and non-atmospheric data. in fact, Knowledge Discovery performs these activities in a logical and predetermined and almost automatic process. The goal of this research is study of uses knowledge Discovery and data mining technique in Iranian climate research. For Achieve This goal, study content (descriptive) analysis and classify base method and issue. The result shown that in climatic research of Iran most clustering, k-means and wards applied and in terms of issues precipitation and atmospheric circulation patterns most introduced. Although several studies in geography and climate issues with statistical techniques such as clustering and pattern extraction is done, Due to the nature of statistics and data mining, but cannot say for

  18. Get Involved in Planetary Discoveries through New Worlds, New Discoveries

    Science.gov (United States)

    Shupla, Christine; Shipp, S. S.; Halligan, E.; Dalton, H.; Boonstra, D.; Buxner, S.; SMD Planetary Forum, NASA

    2013-01-01

    "New Worlds, New Discoveries" is a synthesis of NASA’s 50-year exploration history which provides an integrated picture of our new understanding of our solar system. As NASA spacecraft head to and arrive at key locations in our solar system, "New Worlds, New Discoveries" provides an integrated picture of our new understanding of the solar system to educators and the general public! The site combines the amazing discoveries of past NASA planetary missions with the most recent findings of ongoing missions, and connects them to the related planetary science topics. "New Worlds, New Discoveries," which includes the "Year of the Solar System" and the ongoing celebration of the "50 Years of Exploration," includes 20 topics that share thematic solar system educational resources and activities, tied to the national science standards. This online site and ongoing event offers numerous opportunities for the science community - including researchers and education and public outreach professionals - to raise awareness, build excitement, and make connections with educators, students, and the public about planetary science. Visitors to the site will find valuable hands-on science activities, resources and educational materials, as well as the latest news, to engage audiences in planetary science topics and their related mission discoveries. The topics are tied to the big questions of planetary science: how did the Sun’s family of planets and bodies originate and how have they evolved? How did life begin and evolve on Earth, and has it evolved elsewhere in our solar system? Scientists and educators are encouraged to get involved either directly or by sharing "New Worlds, New Discoveries" and its resources with educators, by conducting presentations and events, sharing their resources and events to add to the site, and adding their own public events to the site’s event calendar! Visit to find quality resources and ideas. Connect with educators, students and the public to

  19. Una mirada a Donde ladrón no llega de Luis Hernáez

    Directory of Open Access Journals (Sweden)

    Nini Johanna Sánchez Ávila

    2006-01-01

    Full Text Available En 1996 aparece publicada la obra Donde ladrón no llega, del escritor paraguayo Luis Hernáez; este trabajo plantea una nueva lectura de la experiencia de las Reducciones Jesuitas en el Paraguay. Es, precisamente, esa forma de valoración en la recreación de la historia la que motiva este texto, ya que presenta una reconstrucción y una mirada crítica sobre un proyecto utópico adelantado en América. Tal propuesta es evaluada desde las voces de aquellos que –aún siendo protagonistas directos del evento social- no tuvieron una voz que se destacara en la delimitación de esta experiencia. Así, se abordará qué tipo de visión de la historia plantea el autor y cómo esta perspectiva se desarrolla en torno a una concepción específica de la propuesta de la utopía para América Latina.

  20. 13 CFR 134.213 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Discovery. 134.213 Section 134.213... OFFICE OF HEARINGS AND APPEALS Rules of Practice for Most Cases § 134.213 Discovery. (a) Motion. A party may obtain discovery only upon motion, and for good cause shown. (b) Forms. The forms of discovery...

  1. 31 CFR 16.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 1 2010-07-01 2010-07-01 false Discovery. 16.21 Section 16.21 Money... FRAUD CIVIL REMEDIES ACT OF 1986 § 16.21 Discovery. (a) The following types of discovery are authorized... to require the creation of a document. (c) Unless mutually agreed to by the parties, discovery is...

  2. Neogene Tiporco Volcanic Complex, San Luis, Argentina: An explosive event in a regional transpressive - local transtensive setting in the pampean flat slab

    Science.gov (United States)

    Ibañes, Oscar Damián; Sruoga, Patricia; Japas, María Silvia; Urbina, y. Nilda Esther

    2017-07-01

    The Neogene Tiporco Volcanic Complex (TVC) is located in the Sierras Pampeanas of San Luis, Argentina, at the southeast of the Pampean flat-slab segment. Based on the comprehensive study of lithofacies and structures, the reconstruction of the volcanic architecture has been carried out. The TVC has been modeled in three subsequent stages: 1) initial updoming, 2) ignimbritic eruptive activity and 3) lava dome emplacement. Interplay of magma injection and transtensional tectonic deformation has been invoked to reproduce TVC evolution.

  3. Luis G. Urbina, la definición de un género literario

    Directory of Open Access Journals (Sweden)

    Ernesto Emiliano Romero

    2016-01-01

    Full Text Available El artículo es una aproximación crítica a las crónicas del autor mexicano Luis G. Urbina; investigación que encontró su origen en la importancia de la crónica modernista como espacio creativo y reflexivo cuyas características y alcances aún hoy generan un sinnúmero de trabajos críticos. Tanto José Martí como Manuel Gutiérrez Nájera y otros de los autores emblemáticos del modernismo, han sido escrutados y valorados a lo largo de estos años. Sin embargo, Urbina ha permanecido relegado a las historias de la literatura y a las bibliotecas, lo cual sugiere un casi nulo conocimiento de su obra. En este ensayo se analizan algunos de los textos incluidos en su libro Cuentos vividos y crónicas soñadas, publicado en 1915, para contribuir a la revalorización y difusión de su obra a 150 años de su nacimiento.

  4. The eolic fluvial succession and paleoclimatic evolution of Rio Conlara, San Luis, Argentina

    International Nuclear Information System (INIS)

    Chiesa, J.

    2004-01-01

    The outcroping deposits in the ravines of the Conlara River are dominated by silt with subordinated and variable percentages of sand and clays. In the section that is described, at the south of the town of Santa Rosa del Conlara, these materials have been deposited responding generally climatic changing conditions. The base of the profile, assigned to the late Pleistocene, contains extint fauna of the Lujanense and a datation of 8950 B.P., and it is represented by fluvial sandy gravels. The overlaying succession, assigned to the Holocene, shows an intercalation of horizons generated by eolic-loessic deposits and deposits with development of pedogenetic processes. The whole succession shows characteristic of corresponding to a vegetated plain, next to the river flood plain. The discriminated horizons are the result of a detailed sampling and the representation of range parameters of the same ones, in function of the depth, this last one oscillates between 6 and 8 meters. The quaternary deposits of the region, support indistinctly as on the crystalline basement of San Luis range, as on the calcretes assigned to the Neogene [es

  5. Rationality in discovery : a study of logic, cognition, computation and neuropharmacology

    NARCIS (Netherlands)

    Bosch, Alexander Petrus Maria van den

    2001-01-01

    Part I Introduction The specific problem adressed in this thesis is: what is the rational use of theory and experiment in the process of scientific discovery, in theory and in the practice of drug research for Parkinson’s disease? The thesis aims to answer the following specific questions: what is:

  6. Nacionalismo maya y descolonización política: Luis de Lión y El tiempo principia en Xibalbá

    OpenAIRE

    del Valle Escalante, Emilio; University of North Carolina, Chapel Hill

    2015-01-01

    Este artículo analiza la novela El tiempo principia en Xibalbá (1985) del escritor maya kaqchikel Luis de Lión (1939-1984), considerada la primera novela escrita por un escritor maya en Guatemala. Leída como una de las primeras manifestaciones epistemológicas y políticas del llamado Movimiento Maya en Guatemala, la obra de Lión, como se argumenta en este trabajo, desmitifica y desarticula construcciones tradicionales y estereotipadas del mundo indígena en el discurso indigenista (la literatur...

  7. Decades of Discovery

    Science.gov (United States)

    2011-06-01

    For the past two-and-a-half decades, the Office of Science at the U.S. Department of Energy has been at the forefront of scientific discovery. Over 100 important discoveries supported by the Office of Science are represented in this document.

  8. Discovery and the atom

    International Nuclear Information System (INIS)

    1989-01-01

    ''Discovery and the Atom'' tells the story of the founding of nuclear physics. This programme looks at nuclear physics up to the discovery of the neutron in 1932. Animation explains the science of the classic experiments, such as the scattering of alpha particles by Rutherford and the discovery of the nucleus. Archive film shows the people: Lord Rutherford, James Chadwick, Marie Curie. (author)

  9. Real-Time Water Quality Monitoring and Habitat Assessment in theSan Luis National Wildlife Refuge

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, Nigel W.T.; Hanlon, Jeremy S.; Burns, Josephine R.; Stromayer, Karl A.K.; Jordan, Brandon M.; Ennis, Mike J.; Woolington,Dennis W.

    2005-08-28

    The project report describes a two year experiment to control wetland drainage to the San Joaquin River of California from the San Luis National Wildlife Refuge using a decision support system for real-time water quality management. This system required the installation and operation of one inlet and three drainage flow and water quality monitoring stations which allowed a simple mass balance model to be developed of the seasonally managed wetlands in the study area. Remote sensing methods were developed to document long-term trends in wetland moist soil vegetation and soil salinity in response to management options such as delaying the initiation of seasonal wetland drainage. These environmental management tools provide wetland managers with some of the tools necessary to improve salinity conditions in the San Joaquin River and improve compliance with State mandated salinity objectives without inflicting long-term harm on the wild fowl habitat resource.

  10. Semantic based cluster content discovery in description first clustering algorithm

    International Nuclear Information System (INIS)

    Khan, M.W.; Asif, H.M.S.

    2017-01-01

    In the field of data analytics grouping of like documents in textual data is a serious problem. A lot of work has been done in this field and many algorithms have purposed. One of them is a category of algorithms which firstly group the documents on the basis of similarity and then assign the meaningful labels to those groups. Description first clustering algorithm belong to the category in which the meaningful description is deduced first and then relevant documents are assigned to that description. LINGO (Label Induction Grouping Algorithm) is the algorithm of description first clustering category which is used for the automatic grouping of documents obtained from search results. It uses LSI (Latent Semantic Indexing); an IR (Information Retrieval) technique for induction of meaningful labels for clusters and VSM (Vector Space Model) for cluster content discovery. In this paper we present the LINGO while it is using LSI during cluster label induction and cluster content discovery phase. Finally, we compare results obtained from the said algorithm while it uses VSM and Latent semantic analysis during cluster content discovery phase. (author)

  11. 29 CFR 2700.56 - Discovery; general.

    Science.gov (United States)

    2010-07-01

    ...(c) or 111 of the Act has been filed. 30 U.S.C. 815(c) and 821. (e) Completion of discovery... 29 Labor 9 2010-07-01 2010-07-01 false Discovery; general. 2700.56 Section 2700.56 Labor... Hearings § 2700.56 Discovery; general. (a) Discovery methods. Parties may obtain discovery by one or more...

  12. BayesMotif: de novo protein sorting motif discovery from impure datasets.

    Science.gov (United States)

    Hu, Jianjun; Zhang, Fan

    2010-01-18

    Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regulated by protein sorting signals in different forms. A major category of sorting signals are amino acid sub-sequences usually located at the N-terminals or C-terminals of protein sequences. Genome-wide experimental identification of protein sorting signals is extremely time-consuming and costly. Effective computational algorithms for de novo discovery of protein sorting signals is needed to improve the understanding of protein sorting mechanisms. We formulated the protein sorting motif discovery problem as a classification problem and proposed a Bayesian classifier based algorithm (BayesMotif) for de novo identification of a common type of protein sorting motifs in which a highly conserved anchor is present along with a less conserved motif regions. A false positive removal procedure is developed to iteratively remove sequences that are unlikely to contain true motifs so that the algorithm can identify motifs from impure input sequences. Experiments on both implanted motif datasets and real-world datasets showed that the enhanced BayesMotif algorithm can identify anchored sorting motifs from pure or impure protein sequence dataset. It also shows that the false positive removal procedure can help to identify true motifs even when there is only 20% of the input sequences containing true motif instances. We proposed BayesMotif, a novel Bayesian classification based algorithm for de novo discovery of a special category of anchored protein sorting motifs from impure datasets. Compared to conventional motif discovery algorithms such as MEME, our algorithm can find less-conserved motifs with short highly conserved anchors. Our algorithm also has the advantage of easy incorporation of additional meta-sequence features such as hydrophobicity or charge of the motifs which may help to overcome the limitations of

  13. El manejo de los residuos sólidos municipales: un enfoque antropológico. El caso de San Luis Potosí, México

    Directory of Open Access Journals (Sweden)

    Mauricio Guzmán Chávez

    2012-01-01

    Full Text Available El artículo presenta una revisión crítica de la literatura especializada en la gestión de residuos sólidos municipales y una reflexión sobre los aspectos políticos vinculados a dicha gestión. Ello, a partir de un estudio de caso: el tiradero Peñasco situado en la periferia de la zona metropolitana de San Luis Potosí. La reflexión se enfoca, particularmente, en las estrategias empleadas por los pepenadores (separadores de basura para defender su fuente de trabajo, esto es, en sus luchas y negociaciones para incidir en la política municipal y en las decisiones gerenciales de la empresa habilitada para administrar dicho sitio. Nuestro análisis ofrece evidencia sobre las dificultades y la insuficiencia de los enfoques propuestos desde la ingeniería ambiental para generar cambios en la gestión de residuos sólidos y muestra el papel decisivo que juegan los intereses y percepciones de los distintos actores en la definición del control territorial y la solución de la disposición final de residuos en tanto problemática social.

  14. On the Shores of the Revolution: Martín Luis Guzmán in Madrid (1915

    Directory of Open Access Journals (Sweden)

    Susana Quintanilla

    2014-07-01

    Full Text Available 1915 is considered a decisive year in world history. Underneath wartime plundering, eighteenth-century beliefs in social progress and human civilization collapsed, and other political and philosophical credos sprouted, while aesthetic avant-gardes created new forms of artistic and literary expression. That same year, from his exile in Madrid, Martín Luis Guzmán would define the coordinates that would guide his life, while trying to assimilate his recent experiences during the Mexican Revolution and make way as a writer, under the immediate protection of Alfonso Reyes and the far-away but determining one of Pedro Henríquez Ureña. Without abandoning his political vocation and remaining open to new trends, Guzmán drew up his own path, which would lead him alongside his mentors and to the forefront of literature in Spanish.

  15. Episodic Late Holocene dune movements on the sand-sheet area, Great Sand Dunes National Park and Preserve, San Luis Valley, Colorado, USA

    Science.gov (United States)

    Forman, S. L.; Spaeth, M.; Marín, L.; Pierson, J.; Gómez, J.; Bunch, F.; Valdez, A.

    2006-07-01

    The Great Sand Dunes National Park and Preserve (GSDNPP) in the San Luis Valley, Colorado, contains a variety of eolian landforms that reflect Holocene drought variability. The most spectacular is a dune mass banked against the Sangre de Cristo Mountains, which is fronted by an extensive sand sheet with stabilized parabolic dunes. Stratigraphic exposures of parabolic dunes and associated luminescence dating of quartz grains by single-aliquot regeneration (SAR) protocols indicate eolian deposition of unknown magnitude occurred ca. 1290-940, 715 ± 80, 320 ± 30, and 200-120 yr ago and in the 20th century. There are 11 drought intervals inferred from the tree-ring record in the past 1300 yr at GSDNPP potentially associated with dune movement, though only five eolian depositional events are currently recognized in the stratigraphic record. There is evidence for eolian transport associated with dune movement in the 13th century, which may coincide with the "Great Drought", a 26-yr-long dry interval identified in the tree ring record, and associated with migration of Anasazi people from the Four Corners areas to wetter areas in southern New Mexico. This nascent chronology indicates that the transport of eolian sand across San Luis Valley was episodic in the late Holocene with appreciable dune migration in the 8th, 10-13th, and 19th centuries, which ultimately nourished the dune mass against the Sangre de Cristo Mountains.

  16. Más allá de la novela realista social: el proyecto destructivo de "Tiempo de silencio" (1961) de Luis Martín-Santos y "Don Julián" (1970) de Juan Goytisolo

    OpenAIRE

    Jordana Darder, Marta

    2018-01-01

    "Tiempo de silencio" (1961) de Luis Martín-Santos y "Reivindicaciones del conde Don Julián" (1970) de Juan Goytisolo son dos novelas de un fuerte compromiso político pero que se desmarcan de los caminos tradicionales del arte compro

  17. Mortality attributable to pandemic influenza A (H1N1) 2009 in San Luis Potosí, Mexico

    Science.gov (United States)

    Comas‐García, Andreu; García‐Sepúlveda, Christian A.; Méndez‐de Lira, José J.; Aranda‐Romo, Saray; Hernández‐Salinas, Alba E.; Noyola, Daniel E.

    2010-01-01

    Please cite this paper as: Comas‐García et al. (2011) Mortality attributable to pandemic influenza A (H1N1) 2009 in San Luis Potosí, Mexico. Influenza and Other Respiratory Viruses 5(2), 76–82. Background  Acute respiratory infections are a leading cause of morbidity and mortality worldwide. Starting in 2009, pandemic influenza A(H1N1) 2009 virus has become one of the leading respiratory pathogens worldwide. However, the overall impact of this virus as a cause of mortality has not been clearly defined. Objectives  To determine the impact of pandemic influenza A(H1N1) 2009 on mortality in a Mexican population. Methods  We assessed the impact of pandemic influenza virus on mortality during the first and second outbreaks in San Luis Potosí, Mexico, and compared it to mortality associated with seasonal influenza and respiratory syncytial virus (RSV) during the previous winter seasons. Results  We estimated that, on average, 8·1% of all deaths that occurred during the 2003–2009 seasons were attributable to influenza and RSV. During the first pandemic influenza A(H1N1) 2009 outbreak, there was an increase in mortality in persons 5–59 years of age, but not during the second outbreak (Fall of 2009). Overall, pandemic influenza A (H1N1) 2009 outbreaks had similar effects on mortality to those associated with seasonal influenza virus epidemics. Conclusions  The impact of influenza A(H1N1) 2009 virus on mortality during the first year of the pandemic was similar to that observed for seasonal influenza. The establishment of real‐time surveillance systems capable of integrating virological, morbidity, and mortality data may result in the timely identification of outbreaks so as to allow for the institution of appropriate control measures to reduce the impact of emerging pathogens on the population. PMID:21306570

  18. A Tale of Two Discoveries: Comparing the Usability of Summon and EBSCO Discovery Service

    Science.gov (United States)

    Foster, Anita K.; MacDonald, Jean B.

    2013-01-01

    Web-scale discovery systems are gaining momentum among academic libraries as libraries seek a means to provide their users with a one-stop searching experience. Illinois State University's Milner Library found itself in the unique position of having access to two distinct discovery products, EBSCO Discovery Service and Serials Solutions' Summon.…

  19. Machine-assisted discovery of relationships in astronomy

    Science.gov (United States)

    Graham, Matthew J.; Djorgovski, S. G.; Mahabal, Ashish A.; Donalek, Ciro; Drake, Andrew J.

    2013-05-01

    High-volume feature-rich data sets are becoming the bread-and-butter of 21st century astronomy but present significant challenges to scientific discovery. In particular, identifying scientifically significant relationships between sets of parameters is non-trivial. Similar problems in biological and geosciences have led to the development of systems which can explore large parameter spaces and identify potentially interesting sets of associations. In this paper, we describe the application of automated discovery systems of relationships to astronomical data sets, focusing on an evolutionary programming technique and an information-theory technique. We demonstrate their use with classical astronomical relationships - the Hertzsprung-Russell diagram and the Fundamental Plane of elliptical galaxies. We also show how they work with the issue of binary classification which is relevant to the next generation of large synoptic sky surveys, such as the Large Synoptic Survey Telescope (LSST). We find that comparable results to more familiar techniques, such as decision trees, are achievable. Finally, we consider the reality of the relationships discovered and how this can be used for feature selection and extraction.

  20. Network-based approaches to climate knowledge discovery

    Science.gov (United States)

    Budich, Reinhard; Nyberg, Per; Weigel, Tobias

    2011-11-01

    Climate Knowledge Discovery Workshop; Hamburg, Germany, 30 March to 1 April 2011 Do complex networks combined with semantic Web technologies offer the next generation of solutions in climate science? To address this question, a first Climate Knowledge Discovery (CKD) Workshop, hosted by the German Climate Computing Center (Deutsches Klimarechenzentrum (DKRZ)), brought together climate and computer scientists from major American and European laboratories, data centers, and universities, as well as representatives from industry, the broader academic community, and the semantic Web communities. The participants, representing six countries, were concerned with large-scale Earth system modeling and computational data analysis. The motivation for the meeting was the growing problem that climate scientists generate data faster than it can be interpreted and the need to prepare for further exponential data increases. Current analysis approaches are focused primarily on traditional methods, which are best suited for large-scale phenomena and coarse-resolution data sets. The workshop focused on the open discussion of ideas and technologies to provide the next generation of solutions to cope with the increasing data volumes in climate science.

  1. DIAGNOSIS OF TICS IN THE SMALLS OF THE CITY OF SAN LUIS POTOSÍ IN THE FOOD AND BEVERAGE SECTOR FOR THE DISSEMINATION OF ITS SERVICES

    Directory of Open Access Journals (Sweden)

    Dubelza B. Oliva-Garza

    2017-07-01

    Full Text Available In recent years information and communication technologies are present in all sectors of our lives and the food and drink sector is no exception, so a diagnosis was made in this area in small and medium enterprises in the city of San Luis Potosí in the areas for the management and dissemination of their services, as they are currently at a disadvantage in front of large restaurant chains that have mobile applications, web pages and other applications. The research design applied is descriptive. Thirty-two MSMEs from the food and beverage sector in the city of San Luis Potosí were affiliated with the National Chamber of the restaurant and food industry (Canirac. The variables that were taken into consideration are: Use of computer equipment, ICT specialists, Internet access and use, Social Media, Electronic Commerce. The study found that most SMEs in the restaurant sector, use the social network Facebook as a means of disseminating services and promotions, However, they do not use all the potential that the social tool provides them, due to the lack of knowledge and lack of preparation to interact better with their customers and suppliers. In addition, most of the sample has the need to advertise through electronic means, through mobile phone applications.

  2. Concept Formation in Scientific Knowledge Discovery from a Constructivist View

    Science.gov (United States)

    Peng, Wei; Gero, John S.

    The central goal of scientific knowledge discovery is to learn cause-effect relationships among natural phenomena presented as variables and the consequences their interactions. Scientific knowledge is normally expressed as scientific taxonomies and qualitative and quantitative laws [1]. This type of knowledge represents intrinsic regularities of the observed phenomena that can be used to explain and predict behaviors of the phenomena. It is a generalization that is abstracted and externalized from a set of contexts and applicable to a broader scope. Scientific knowledge is a type of third-person knowledge, i.e., knowledge that independent of a specific enquirer. Artificial intelligence approaches, particularly data mining algorithms that are used to identify meaningful patterns from large data sets, are approaches that aim to facilitate the knowledge discovery process [2]. A broad spectrum of algorithms has been developed in addressing classification, associative learning, and clustering problems. However, their linkages to people who use them have not been adequately explored. Issues in relation to supporting the interpretation of the patterns, the application of prior knowledge to the data mining process and addressing user interactions remain challenges for building knowledge discovery tools [3]. As a consequence, scientists rely on their experience to formulate problems, evaluate hypotheses, reason about untraceable factors and derive new problems. This type of knowledge which they have developed during their career is called "first-person" knowledge. The formation of scientific knowledge (third-person knowledge) is highly influenced by the enquirer's first-person knowledge construct, which is a result of his or her interactions with the environment. There have been attempts to craft automatic knowledge discovery tools but these systems are limited in their capabilities to handle the dynamics of personal experience. There are now trends in developing

  3. [Dr. Luis Cifuentes Delatte. Memories and teaching].

    Science.gov (United States)

    Pérez Albacete, Mariano

    2008-12-01

    With the celebration of the centenary of the birth of Dr. Luis Cifuentes Delatte, due to his great scientific personality, we want to emphasize two features that, taken from his works and memories, we consider have not been emphasized enough: his role as historian of urology, both for the histories he narrated of his life experiences and the historical exposition of several pathologies, and also his teaching as professor of several generations of urologists, with the objective of trying to get to know his great human quality as he demonstrated over his life and showed in his writings. We review his books and works, lectures and published papers, in addition the news about his person we have collected from the media, and after analysis, mainly of his memories, we extract data reflecting his personality, and they way he thought and behaved. Since he was young he went with his father to the international urology meetings where he met a great number of personalities in the World of Urology; he extended his training with them, and later on they got to have a great relationship. He travelled around Europe and United States before and after Second World War, respectively, with stays in the most prestigious centers, which he described meticulously. He also reported his activity during the first two years he directed the Department of Urology at the Hospital La Princesa in Madrid and cited the series of collaborators he had. In his research works he made an ample description of historical development as introduction to the various pathologies he analyzed in depth. The reading of the narration of his trips, that he did in the convulse International time he lived, offers details which enable us to know firsthand the situation of urology and the human side of the actors he had relation with, and the social life they had, in addition to data about their families and daily life. As a researcher in transcendental chapters in urological pathology we emphasize his historical

  4. 29 CFR 2200.208 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 9 2010-07-01 2010-07-01 false Discovery. 2200.208 Section 2200.208 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW COMMISSION RULES OF PROCEDURE Simplified Proceedings § 2200.208 Discovery. Discovery, including requests for admissions, will only be...

  5. 47 CFR 65.105 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 3 2010-10-01 2010-10-01 false Discovery. 65.105 Section 65.105... OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Procedures § 65.105 Discovery. (a) Participants... evidence. (c) Discovery requests pursuant to § 65.105(b), including written interrogatories, shall be filed...

  6. 49 CFR 209.313 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Discovery. 209.313 Section 209.313 Transportation... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES Disqualification Procedures § 209.313 Discovery. (a... parties. Discovery is designed to enable a party to obtain relevant information needed for preparation of...

  7. La acción tutorial desde la perspectiva de los alumnos de la Universidad Autónoma de San Luis Potosí

    OpenAIRE

    Rubio, Perla Patricia; Martínez, José Francisco

    2012-01-01

    Este estudio constituye una propuesta de corte cualitativo para explorar los ejes de racionalidad con que los alumnos de la Universidad Autónoma de San Luis Potosí (UASLP) construyen sus concepciones y expectativas, y analizan las implicaciones de la acción tutorial que los programas de tutoría implementan en su institución. De los resultados generados se encontró que los alumnos conceptualizan la acción tutorial en cinco ámbitos de atención: a) académico profesional, b) escolar y de aprendiz...

  8. Modelo sistémico de planeamiento estratégico con enfoque de sustainability Scorecard aplicado a la Universidad Nacional San Luis Gonzaga

    OpenAIRE

    Cáceres Huamán, Juan Félix; Cáceres Huamán, Juan Félix; Cáceres Huamán, Juan Félix

    2011-01-01

    En el presente trabajo de investigación, se expone la concepción sistémica del planeamiento estratégico, como metodología y herramienta de gestión empresarial, a fin que la Universidad Nacional "San Luis Gonzaga", logre una gestión estratégica, académica y administrativa, eficiente, eficaz y de calidad, para alcanzar un desarrollo y crecimiento sostenible. También se plantea la estrategia del balance de sostenibilidad (Sustainability Scorecard "SSC"), que postula la integración de lo econ...

  9. Estructura y composición de la vegetación del bosque de niebla de Copalillos, San Luis Potosí, México

    OpenAIRE

    Fortanelli-Martínez, Javier; García-Pérez, José; Castillo-Lara, Pedro

    2014-01-01

    Se presenta la lista florística y se describe la estructura de un bosque de niebla en Copalillos, San Luis Potosí, el cual, hasta hace muy poco tiempo estuvo ausente en la cartografía de vegetación existente. Se registraron 199 especies, correspondientes a 165 géneros y 91 familias botánicas. La estructura vertical mostró tres estratos arbóreos, uno arbustivo y otro herbáceo. Las especies dominantes en el arbóreo superior fueron Liquidambar styraciflua, Quercus germana y Q. pinnativenulosa. E...

  10. ["Unintended consequences of scientific discoveries" or: "Heterogeny of purposes" as phenomena of the history of science].

    Science.gov (United States)

    Wittkau-Horgby, A

    2001-01-01

    This paper deals with an old observation in respect to man's action--the problem of unintended consequences of human action. It presents the scientific approaches to this phenomenon in the 18th century and focusses then on the problem of unintended consequences of scientific discoveries. Using the prominent examples of Copernicus and Darwin the author shows that the actual outcomes and final effects of scientific discoveries must not necessarily be the originally intended ones. On the contrary, especially those results of scientific discoveries which have affected the sphere of world view (Weltanschauung) like the research works of Copernicus and Darwin were originally meant to be only scientific studies. The final results in respect to the world view were on Copernicus' side not even realized and on Darwin's side neither intended nor welcomed. The conclusion of this analysis is that due to the fact that both scientists did not have the intention to change the world view they can only partly be regarded to be responsible for the fundamental changes they finally caused.

  11. Quantifying the Ease of Scientific Discovery.

    Science.gov (United States)

    Arbesman, Samuel

    2011-02-01

    It has long been known that scientific output proceeds on an exponential increase, or more properly, a logistic growth curve. The interplay between effort and discovery is clear, and the nature of the functional form has been thought to be due to many changes in the scientific process over time. Here I show a quantitative method for examining the ease of scientific progress, another necessary component in understanding scientific discovery. Using examples from three different scientific disciplines - mammalian species, chemical elements, and minor planets - I find the ease of discovery to conform to an exponential decay. In addition, I show how the pace of scientific discovery can be best understood as the outcome of both scientific output and ease of discovery. A quantitative study of the ease of scientific discovery in the aggregate, such as done here, has the potential to provide a great deal of insight into both the nature of future discoveries and the technical processes behind discoveries in science.

  12. Archosauriform remains from the Late Triassic of San Luis province, Argentina, Quebrada del Barro Formation, Marayes-El Carrizal Basin

    Science.gov (United States)

    Gianechini, Federico A.; Codorniú, Laura; Arcucci, Andrea B.; Castillo Elías, Gabriela; Rivarola, David

    2016-03-01

    Here we present archosauriform remains from 'Abra de los Colorados', a fossiliferous locality at Sierra de Guayaguas, NW San Luis Province. Two fossiliferous levels were identified in outcrops of the Quebrada del Barro Formation (Norian), which represent the southernmost outcrops of the Marayes-El Carrizal Basin. These levels are composed by massive muddy lithofacies, interpreted as floodplain deposits. The specimens consist of one incomplete maxilla (MIC-V718), one caudal vertebra (MIC-V719), one metatarsal (MIC-V720) and one indeterminate appendicular bone (MIC-V721). The materials can be assigned to Archosauriformes but the fragmentary nature and lack of unambiguous synapomorphies preclude a more precise taxomic assignment. The maxilla is remarkably large and robust and represents the posterior process. It preserved one partially erupted tooth with ziphodont morphology. This bone shows some anatomical traits and size match with 'rauisuchians' and theropods. MIC-V719 corresponds to a proximal caudal vertebra. It has a high centrum, a ventral longitudinal furrow, expanded articular processes for the chevrons, a posteriorly displaced diapophysis located below the level of the prezygapophyses, and short prezygapophyses. This vertebra would be from an indeterminate archosauriform. MIC-V720 presents a cylindrical diaphysis, with a well-developed distal trochlea, which present resemblances with metatarsals of theropods, pseudosuchians, and silesaurids, although the size matches better with theropods. MIC-V721 has a slender diaphysis and a convex triangular articular surface, and corresponds to an indeterminate archosauriform. Despite being fragmentary, these materials indicate the presence of a diverse archosauriforms association from Late Triassic beds of San Luis. Thus, they add to the faunal assemblage recently reported from this basin at San Juan Province, which is much rich and diverse than the coeval paleofauna well known from Los Colorados Formation in the

  13. 15 CFR 280.210 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 1 2010-01-01 2010-01-01 false Discovery. 280.210 Section 280.210... STANDARDS AND TECHNOLOGY, DEPARTMENT OF COMMERCE ACCREDITATION AND ASSESSMENT PROGRAMS FASTENER QUALITY Enforcement § 280.210 Discovery. (a) General. The parties are encouraged to engage in voluntary discovery...

  14. Colección permanente del Banco de la República. Biblioteca Luis Ángel Arango. Casa de Exposiciones

    Directory of Open Access Journals (Sweden)

    Benhur Sánchez Suárez

    1996-05-01

    Full Text Available Desde cuando dejé mi provincia natal y me radiqué en Bogotá, con mis sueños de artista y de escritor, la Biblioteca Luis Ángel Arango fue uno de mis polos de atracción. Y es algo muy simple de entender: por un lado mi ansiedad visual por todo lo que fuera pintura y, por otro, porque en sus salones se realizaron gran parte de las mejores exposiciones de la época - importancia que compartió con el Museo de Arte Moderno y algunas galerías privadas- y es casi obvio que hacia ellos dirigiera mi interés, como lo hicieran tantos colombianos amantes de las artes plásticas y creyentes de nuestro desarrollo cultural.

  15. 10 CFR 1013.21 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Discovery. 1013.21 Section 1013.21 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) PROGRAM FRAUD CIVIL REMEDIES AND PROCEDURES § 1013.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and...

  16. 37 CFR 2.120 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Discovery. 2.120 Section 2... COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Procedure in Inter Partes Proceedings § 2.120 Discovery. (a... to disclosure and discovery shall apply in opposition, cancellation, interference and concurrent use...

  17. 46 CFR 550.502 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 9 2010-10-01 2010-10-01 false Discovery. 550.502 Section 550.502 Shipping FEDERAL... Proceedings § 550.502 Discovery. The Commission may authorize a party to a proceeding to use depositions, written interrogatories, and discovery procedures that, to the extent practicable, are in conformity with...

  18. 15 CFR 785.8 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 15 Commerce and Foreign Trade 2 2010-01-01 2010-01-01 false Discovery. 785.8 Section 785.8... INDUSTRY AND SECURITY, DEPARTMENT OF COMMERCE ADDITIONAL PROTOCOL REGULATIONS ENFORCEMENT § 785.8 Discovery. (a) General. The parties are encouraged to engage in voluntary discovery regarding any matter, not...

  19. 22 CFR 35.21 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Discovery. 35.21 Section 35.21 Foreign Relations DEPARTMENT OF STATE CLAIMS AND STOLEN PROPERTY PROGRAM FRAUD CIVIL REMEDIES § 35.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for...

  20. 45 CFR 96.65 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discovery. 96.65 Section 96.65 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION BLOCK GRANTS Hearing Procedure § 96.65 Discovery. The use of interrogatories, depositions, and other forms of discovery shall not be allowed. ...

  1. 49 CFR 31.21 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 1 2010-10-01 2010-10-01 false Discovery. 31.21 Section 31.21 Transportation Office of the Secretary of Transportation PROGRAM FRAUD CIVIL REMEDIES § 31.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and...

  2. 43 CFR 4.1130 - Discovery methods.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Discovery methods. 4.1130 Section 4.1130... Special Rules Applicable to Surface Coal Mining Hearings and Appeals Discovery § 4.1130 Discovery methods. Parties may obtain discovery by one or more of the following methods— (a) Depositions upon oral...

  3. Espacios Rurales ¿Crisis sistémica o brotes verdes? Entrevista con Luis Camarero.

    Directory of Open Access Journals (Sweden)

    Luis Camarero Rioja

    2013-12-01

    Full Text Available Entrevista a Luis Camarero Rioja es Catedrático de Sociología de la UNED. Experto en sociología rural desde que iniciara en los años 90 su trayectoria como investigador en el Seminario de Estudios Rurales impulsado por Josechu Vicente-Mazariegos (UCM. Recibió el Premio Nacional de Investigaciones Agrarias (1993, MAPA y el Premio de Tesis Doctorales (1993, Colegio de Sociólogos. Ha dirigido distintos proyectos de investigación dedicados especialmente a la visibilización del trabajo femenino en áreas rurales y a la sostenibilidad social en el mundo rural. Autor de numerosas publicaciones de referencia como Del éxodo rural y del éxodo urbano (1993. Madrid: Ministerio de Agricultura, La población rural de España. De los desequilibrios a la sostenibilidad social (2009. Barcelona: La Caixa o “Foreigners, Neighbours, Immigrants: Translocal mobilities in rural areas in Spain” en Translocal Ruralism, obra editada por Hedberg y Carmo (2012. London: Springer.

  4. El proceso de negociación entre el Gobierno y ETA durante la etapa de José Luis Rodríguez Zapatero (2004-2011

    Directory of Open Access Journals (Sweden)

    Aleix Romero Peña

    2013-02-01

    Full Text Available Tras producirse el anuncio por parte de ETA del abandono de la lucha armada (20 de octubre 2011, hay que hacer balance de la política antiterrorista de José Luis Rodríguez Zapatero, basada en el uso de todas las vías para hacer posible la paz, incluido el diálogo. ¿Fue una estrategia equivocada? ¿Contribuyó a la declaración de ETA? El fracaso del proceso de negociación y el ruido mediático han ocultado las consecuencias positivas que tuvo para impulsar un cambio de estrategia en la izquierda abertzale que potenciara una lucha política ajena a las armas.Palabras Clave:_________________________ After the ETA´s announcement about the end of the armed conflict (20 October 2011, it´s necessary to make an evaluation of the antiterrorist policy in terms of office of José Luis Rodríguez Zapatero, which was based on use of all the ways to make peace, including dialogue. Was a wrong strategy or contributed to the declaration of ETA? The failure of negociation process and mediatical controversies have concealled that this strategy had positive consequences and impelled a change in the izquierda abertzale to boost a political struggle completely alien to weapons.Keywords:

  5. Testing jumps via false discovery rate control.

    Science.gov (United States)

    Yen, Yu-Min

    2013-01-01

    Many recently developed nonparametric jump tests can be viewed as multiple hypothesis testing problems. For such multiple hypothesis tests, it is well known that controlling type I error often makes a large proportion of erroneous rejections, and such situation becomes even worse when the jump occurrence is a rare event. To obtain more reliable results, we aim to control the false discovery rate (FDR), an efficient compound error measure for erroneous rejections in multiple testing problems. We perform the test via the Barndorff-Nielsen and Shephard (BNS) test statistic, and control the FDR with the Benjamini and Hochberg (BH) procedure. We provide asymptotic results for the FDR control. From simulations, we examine relevant theoretical results and demonstrate the advantages of controlling the FDR. The hybrid approach is then applied to empirical analysis on two benchmark stock indices with high frequency data.

  6. 6 CFR 13.21 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 6 Domestic Security 1 2010-01-01 2010-01-01 false Discovery. 13.21 Section 13.21 Domestic Security DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY PROGRAM FRAUD CIVIL REMEDIES § 13.21 Discovery. (a) In general. (1) The following types of discovery are authorized: (i) Requests for production of...

  7. 45 CFR 99.23 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discovery. 99.23 Section 99.23 Public Welfare... DEVELOPMENT FUND Hearing Procedures § 99.23 Discovery. The Department, the Lead Agency, and any individuals or groups recognized as parties shall have the right to conduct discovery (including depositions) against...

  8. 20 CFR 355.21 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Discovery. 355.21 Section 355.21 Employees... UNDER THE PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 355.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  9. 10 CFR 2.1018 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 1 2010-01-01 2010-01-01 false Discovery. 2.1018 Section 2.1018 Energy NUCLEAR REGULATORY... Geologic Repository § 2.1018 Discovery. (a)(1) Parties, potential parties, and interested governmental participants in the high-level waste licensing proceeding may obtain discovery by one or more of the following...

  10. 28 CFR 71.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Discovery. 71.21 Section 71.21 Judicial... REMEDIES ACT OF 1986 Implementation for Actions Initiated by the Department of Justice § 71.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for...

  11. 13 CFR 134.310 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Discovery. 134.310 Section 134.310 Business Credit and Assistance SMALL BUSINESS ADMINISTRATION RULES OF PROCEDURE GOVERNING CASES BEFORE THE... Designations § 134.310 Discovery. Discovery will not be permitted in appeals from size determinations or NAICS...

  12. 34 CFR 33.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Discovery. 33.21 Section 33.21 Education Office of the Secretary, Department of Education PROGRAM FRAUD CIVIL REMEDIES ACT § 33.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying...

  13. 28 CFR 18.7 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Discovery. 18.7 Section 18.7 Judicial Administration DEPARTMENT OF JUSTICE OFFICE OF JUSTICE PROGRAMS HEARING AND APPEAL PROCEDURES § 18.7 Discovery.... Such order may be entered upon a showing that the deposition is necessary for discovery purposes, and...

  14. 7 CFR 1.322 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 1 2010-01-01 2010-01-01 false Discovery. 1.322 Section 1.322 Agriculture Office of... Under the Program Fraud Civil Remedies Act of 1986 § 1.322 Discovery. (a) The following types of discovery are authorized: (1) Requests for production, inspection and photocopying of documents; (2...

  15. 45 CFR 1386.103 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 4 2010-10-01 2010-10-01 false Discovery. 1386.103 Section 1386.103 Public... Hearing Procedures § 1386.103 Discovery. The Department and any party named in the Notice issued pursuant to § 1386.90 has the right to conduct discovery (including depositions) against opposing parties as...

  16. 45 CFR 79.21 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discovery. 79.21 Section 79.21 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATION PROGRAM FRAUD CIVIL REMEDIES § 79.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for...

  17. 12 CFR 308.520 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Discovery. 308.520 Section 308.520 Banks and... PROCEDURE Program Fraud Civil Remedies and Procedures § 308.520 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  18. 47 CFR 1.729 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Discovery. 1.729 Section 1.729..., and Reports Involving Common Carriers Formal Complaints § 1.729 Discovery. (a) Subject to paragraph (i... seek discovery of any non-privileged matter that is relevant to the material facts in dispute in the...

  19. 7 CFR 283.12 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 4 2010-01-01 2010-01-01 false Discovery. 283.12 Section 283.12 Agriculture... of $50,000 or More § 283.12 Discovery. (a) Dispositions—(1) Motion for taking deposition. Only upon a... exist if the information sought appears reasonably calculated to lead to the discovery of admissible...

  20. Knowledge Discovery Process: Case Study of RNAV Adherence of Radar Track Data

    Science.gov (United States)

    Matthews, Bryan

    2018-01-01

    This talk is an introduction to the knowledge discovery process, beginning with: identifying the problem, choosing data sources, matching the appropriate machine learning tools, and reviewing the results. The overview will be given in the context of an ongoing study that is assessing RNAV adherence of commercial aircraft in the national airspace.

  1. Máscaras de la lectura: Jorge Luis Borges en la obra de Mario Luzi / The masks of reading: Jeorge Luis Borges in Mario Luzi’s work

    Directory of Open Access Journals (Sweden)

    Daniel Clemente Del Percio

    2014-12-01

    The roads that separate writers often end with a paradox, happy proximity. The nominations for the Nobel Prize for literature in 1979 came together, as in a real literary constellation, Italo Calvino, Alberto Moravia, Giorgio Bassani, Vittorio Sereni, Leonardo Sciascia and Mario Luzi, along with the argentine Jorge Luis Borges. The list reflects the richness and variety of Italian literature of the time. But beyond the storytellers, the coincidence of Luzi and Borges (and we might add, that of Odisseas Elytis, who was finally awarded the prize is a unique convergence of poets, with very different poetics, but with intense communicating vessels that unite them, often invisible and contradictory manner. While Borges never wrote about Luzi, the italian, however, did, and quite often, on the argentine, not only from the pages of literary criticism in «Il Corriere della Sera», space occupied until 1974 commenting Latin American literature (he has written about Roberto Arlt, Vargas Llosa and Juan Rulfo, among other writers, but in different interviews, where the frequent quotations that Luzi makes about Borges often installed a space for discussion and profound differences not only on the nature of poetry, but on the same link with the world and life. We propose to study these reflections that Mario Luzi made from (and on many occasions, against about the Argentine author, from the critical work of the Florentine poet, on the centenary of his birth.

  2. 42 CFR 1005.7 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 5 2010-10-01 2010-10-01 false Discovery. 1005.7 Section 1005.7 Public Health... OF EXCLUSIONS, CIVIL MONEY PENALTIES AND ASSESSMENTS § 1005.7 Discovery. (a) A party may make a... and any forms of discovery, other than those permitted under paragraph (a) of this section, are not...

  3. 29 CFR 1603.210 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 4 2010-07-01 2010-07-01 false Discovery. 1603.210 Section 1603.210 Labor Regulations... GOVERNMENT EMPLOYEE RIGHTS ACT OF 1991 Hearings § 1603.210 Discovery. (a) Unless otherwise ordered by the administrative law judge, discovery may begin as soon as the complaint has been transmitted to the administrative...

  4. 45 CFR 150.435 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discovery. 150.435 Section 150.435 Public Welfare... AND INDIVIDUAL INSURANCE MARKETS Administrative Hearings § 150.435 Discovery. (a) The parties must identify any need for discovery from the opposing party as soon as possible, but no later than the time for...

  5. 34 CFR 81.16 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 1 2010-07-01 2010-07-01 false Discovery. 81.16 Section 81.16 Education Office of the... Discovery. (a) The parties to a case are encouraged to exchange relevant documents and information voluntarily. (b) The ALJ, at a party's request, may order compulsory discovery described in paragraph (c) of...

  6. 29 CFR 1905.25 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Discovery. 1905.25 Section 1905.25 Labor Regulations... OCCUPATIONAL SAFETY AND HEALTH ACT OF 1970 Hearings § 1905.25 Discovery. (a) Depositions. (1) For reasons of... discovery. Whenever appropriate to a just disposition of any issue in a hearing, the presiding hearing...

  7. 12 CFR 1780.26 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Discovery. 1780.26 Section 1780.26 Banks and... OF PRACTICE AND PROCEDURE RULES OF PRACTICE AND PROCEDURE Prehearing Proceedings § 1780.26 Discovery. (a) Limits on discovery. Subject to the limitations set out in paragraphs (b), (d), and (e) of this...

  8. 45 CFR 160.516 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discovery. 160.516 Section 160.516 Public Welfare... ADMINISTRATIVE REQUIREMENTS Procedures for Hearings § 160.516 Discovery. (a) A party may make a request to... forms of discovery, other than those permitted under paragraph (a) of this section, are not authorized...

  9. 42 CFR 430.86 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Discovery. 430.86 Section 430.86 Public Health... Plans and Practice to Federal Requirements § 430.86 Discovery. CMS and any party named in the notice issued under § 430.70 has the right to conduct discovery (including depositions) against opposing parties...

  10. Mental Imagery in Creative Problem Solving.

    Science.gov (United States)

    Polland, Mark J.

    In order to investigate the relationship between mental imagery and creative problem solving, a study of 44 separate accounts reporting mental imagery experiences associated with creative discoveries were examined. The data included 29 different scientists, among them Albert Einstein and Stephen Hawking, and 9 artists, musicians, and writers,…

  11. BLSSpeller: exhaustive comparative discovery of conserved cis-regulatory elements.

    Science.gov (United States)

    De Witte, Dieter; Van de Velde, Jan; Decap, Dries; Van Bel, Michiel; Audenaert, Pieter; Demeester, Piet; Dhoedt, Bart; Vandepoele, Klaas; Fostier, Jan

    2015-12-01

    The accurate discovery and annotation of regulatory elements remains a challenging problem. The growing number of sequenced genomes creates new opportunities for comparative approaches to motif discovery. Putative binding sites are then considered to be functional if they are conserved in orthologous promoter sequences of multiple related species. Existing methods for comparative motif discovery usually rely on pregenerated multiple sequence alignments, which are difficult to obtain for more diverged species such as plants. As a consequence, misaligned regulatory elements often remain undetected. We present a novel algorithm that supports both alignment-free and alignment-based motif discovery in the promoter sequences of related species. Putative motifs are exhaustively enumerated as words over the IUPAC alphabet and screened for conservation using the branch length score. Additionally, a confidence score is established in a genome-wide fashion. In order to take advantage of a cloud computing infrastructure, the MapReduce programming model is adopted. The method is applied to four monocotyledon plant species and it is shown that high-scoring motifs are significantly enriched for open chromatin regions in Oryza sativa and for transcription factor binding sites inferred through protein-binding microarrays in O.sativa and Zea mays. Furthermore, the method is shown to recover experimentally profiled ga2ox1-like KN1 binding sites in Z.mays. BLSSpeller was written in Java. Source code and manual are available at http://bioinformatics.intec.ugent.be/blsspeller Klaas.Vandepoele@psb.vib-ugent.be or jan.fostier@intec.ugent.be. Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

  12. Drug discovery for male subfertility using high-throughput screening: a new approach to an unsolved problem.

    Science.gov (United States)

    Martins da Silva, Sarah J; Brown, Sean G; Sutton, Keith; King, Louise V; Ruso, Halil; Gray, David W; Wyatt, Paul G; Kelly, Mark C; Barratt, Christopher L R; Hope, Anthony G

    2017-05-01

    Can pharma drug discovery approaches be utilized to transform investigation into novel therapeutics for male infertility? High-throughput screening (HTS) is a viable approach to much-needed drug discovery for male factor infertility. There is both huge demand and a genuine clinical need for new treatment options for infertile men. However, the time, effort and resources required for drug discovery are currently exorbitant, due to the unique challenges of the cellular, physical and functional properties of human spermatozoa and a lack of appropriate assay platform. Spermatozoa were obtained from healthy volunteer research donors and subfertile patients undergoing IVF/ICSI at a hospital-assisted reproductive techniques clinic between January 2012 and November 2016. A HTS assay was developed and validated using intracellular calcium ([Ca2+]i) as a surrogate for motility in human spermatozoa. Calcium fluorescence was detected using a Flexstation microplate reader (384-well platform) and compared with responses evoked by progesterone, a compound known to modify a number of biologically relevant behaviours in human spermatozoa. Hit compounds identified following single point drug screen (10 μM) of an ion channel-focussed library assembled by the University of Dundee Drug Discovery Unit were rescreened to ensure potency using standard 10 point half-logarithm concentration curves, and tested for purity and integrity using liquid chromatography and mass spectrometry. Hit compounds were grouped by structure activity relationships and five representative compounds then further investigated for direct effects on spermatozoa, using computer-assisted sperm assessment, sperm penetration assay and whole-cell patch clamping. Of the 3242 ion channel library ligands screened, 384 compounds (11.8%) elicited a statistically significant increase in calcium fluorescence, with greater than 3× median absolute deviation above the baseline. Seventy-four compounds eliciting ≥50% increase

  13. Discovery Driven Growth

    DEFF Research Database (Denmark)

    Bukh, Per Nikolaj

    2009-01-01

    Anmeldelse af Discovery Driven Growh : A breakthrough process to reduce risk and seize opportunity, af Rita G. McGrath & Ian C. MacMillan, Boston: Harvard Business Press. Udgivelsesdato: 14 august......Anmeldelse af Discovery Driven Growh : A breakthrough process to reduce risk and seize opportunity, af Rita G. McGrath & Ian C. MacMillan, Boston: Harvard Business Press. Udgivelsesdato: 14 august...

  14. 42 CFR 405.1037 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 2 2010-10-01 2010-10-01 false Discovery. 405.1037 Section 405.1037 Public Health... Appeals Under Original Medicare (Part A and Part B) Alj Hearings § 405.1037 Discovery. (a) General rules. (1) Discovery is permissible only when CMS or its contractor elects to participate in an ALJ hearing...

  15. 20 CFR 498.207 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Discovery. 498.207 Section 498.207 Employees... § 498.207 Discovery. (a) For the purpose of inspection and copying, a party may make a request to...) Any form of discovery other than that permitted under paragraph (a) of this section, such as requests...

  16. 42 CFR 93.512 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Discovery. 93.512 Section 93.512 Public Health... Process § 93.512 Discovery. (a) Request to provide documents. A party may only request another party to...) Responses to a discovery request. Within 30 days of receiving a request for the production of documents, a...

  17. 42 CFR 3.516 - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Discovery. 3.516 Section 3.516 Public Health PUBLIC... AND PATIENT SAFETY WORK PRODUCT Enforcement Program § 3.516 Discovery. (a) A party may make a request... and any forms of discovery, other than those permitted under paragraph (a) of this section, are not...

  18. 29 CFR 22.21 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Discovery. 22.21 Section 22.21 Labor Office of the Secretary of Labor PROGRAM FRAUD CIVIL REMEDIES ACT OF 1986 § 22.21 Discovery. (a) The following types of discovery are authorized: (1) Requests for production of documents for inspection and copying; (2) Requests...

  19. CONDIÇÕES DE MOBILIDADE URBANA E ACESSIBILIDADE

    Directory of Open Access Journals (Sweden)

    Fabíola de Oliveira Aguiar

    2012-01-01

    Full Text Available The present work aims to discuss about the mobility and accessibility conditions in São Luis / MA, comparing even though superficially São Paulo city in the 60's and São Luis at present. It is noteworthy the fact that Sao Luis still does not have mobility policies implemented, something that is being felt in everyday Iife by users who face more and more problems of urban circulation . The main avenues cannot stand anymore the burst of a growing number of vehicles.

  20. Computational methods in drug discovery

    Directory of Open Access Journals (Sweden)

    Sumudu P. Leelananda

    2016-12-01

    Full Text Available The process for drug discovery and development is challenging, time consuming and expensive. Computer-aided drug discovery (CADD tools can act as a virtual shortcut, assisting in the expedition of this long process and potentially reducing the cost of research and development. Today CADD has become an effective and indispensable tool in therapeutic development. The human genome project has made available a substantial amount of sequence data that can be used in various drug discovery projects. Additionally, increasing knowledge of biological structures, as well as increasing computer power have made it possible to use computational methods effectively in various phases of the drug discovery and development pipeline. The importance of in silico tools is greater than ever before and has advanced pharmaceutical research. Here we present an overview of computational methods used in different facets of drug discovery and highlight some of the recent successes. In this review, both structure-based and ligand-based drug discovery methods are discussed. Advances in virtual high-throughput screening, protein structure prediction methods, protein–ligand docking, pharmacophore modeling and QSAR techniques are reviewed.

  1. 10 CFR 205.198 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Discovery. 205.198 Section 205.198 Energy DEPARTMENT OF... of Proposed Disallowance, and Order of Disallowance § 205.198 Discovery. (a) If a person intends to file a Motion for Discovery, he must file it at the same time that he files his Statement of Objections...

  2. 12 CFR 908.46 - Discovery.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Discovery. 908.46 Section 908.46 Banks and... PRACTICE AND PROCEDURE IN HEARINGS ON THE RECORD Pre-Hearing Proceedings § 908.46 Discovery. (a) Limits on discovery. Subject to the limitations set out in paragraphs (b), (d), and (e) of this section, any party to...

  3. 21 CFR 17.23 - Discovery.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 1 2010-04-01 2010-04-01 false Discovery. 17.23 Section 17.23 Food and Drugs FOOD... HEARINGS § 17.23 Discovery. (a) No later than 60 days prior to the hearing, unless otherwise ordered by the..., depositions, and any forms of discovery, other than those permitted under paragraphs (a) and (e) of this...

  4. U-Pb SHRIMP and {sup 40}Ar/{sup 39}Ar constraints on the timing of mineralization in the Paleoproterozoic Caxias orogenic gold deposit, Sao Luis cratonic fragment, Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Evandro Luiz, E-mail: evandro.klein@cprm.gov.br [Servico Geologico do Brasil (CPRM), Belem, PA (Brazil); Tassinari, Colombo Celso Gaeta, E-mail: ccgtassi@usp.br [Universidade de Sao Paulo (USP), SP (Brazil). Instituto de Geociencias. Centro de Pesquisas Geocronologicas; Vasconcelos, Paulo Marcos, E-mail: paulo@earth.uq.edu.au [University of Queensland, School of Earth Sciences, Brisbane (Australia)

    2014-07-01

    Caxias is an orogenic gold deposit in the Sao Luis cratonic fragment, which is correlated with the Rhyacian terranes of the West-African Craton. The deposit postdates peak metamorphism (estimated at 2100 ± 15 Ma) and is hosted in a shear zone that cuts across schists of the Aurizona Group (2240 ± 5 Ma) and the Caxias Microtonalite. The emplacement age of the microtonalite, as determined in this work by SHRIMP U-Pb zircon dating, is 2009 ± 11 Ma and represents a latest age magmatic event in the Sao Luis cratonic fragment. Older zircon age of 2139 ± 10 Ma is interpreted as due to inheritance from the older granitoid or volcanic suites (magmatic sources?) or to contamination during emplacement. Lead isotope compositions indicate that the Pb incorporated in ore-related pyrite was probably sourced from regional, orogenic calc-alkaline granitoids of ca. 2160 Ma. Hydrothermal sericite from Caxias yielded a {sup 40}Ar/{sup 39}Ar plateau age of 1990 ± 30 Ma, which combined with the emplacement age of the Caxias Microtonalite brackets the age of gold mineralization between 2009 ± 11 and 1990 ± 30 Ma. (author)

  5. Espetáculos e performances culturais no turismo: reflexões sobre o bumba-meu-boi em São Luis, Maranhão (Brasil

    Directory of Open Access Journals (Sweden)

    Karoliny Diniz Carvalho

    2012-01-01

    Full Text Available This article examines the process of revitalization of cultures from the development of cultural tourism. Where the object of study, the Bumba-meu-boi in São Luis, Maranhao, discusses the major changes brought about in this play from its incorporation into the circuit of cultural production and consumption. Based on studies of performance and restoration of behavior, it is understood that the cultural events, like the Valley Celebrate event, consist of renovations on the identities of othercontexts and social spaces, and incorporating in this new meanings.

  6. El dispositivo de concursos para cargos directivos en San Luis como facilitador u obstaculizador para la instalación de nuevos formatos escolares.

    OpenAIRE

    Fratín de Samper, Alicia Celia; Chavero, Gustavo Federico; Celi Quiroga, José Carmelo

    2015-01-01

    El trabajo tiene por objetivo general analizar si el dispositivo de concursos para cargos directivos en escuelas de la provincia de San Luis se constituye en facilitador u obstaculizador para la instalación de nuevos formatos escolares. El análisis se presenta desde dos ópticas. Por un lado, desde un estudio comparativo entre las normativas ministeriales que enmarcaron los Concursos Jerárquicos 2012 (Decreto N° 3895-ME-2012 y la Resolución 211 ME-2012 en lo que refiere a la guía pa...

  7. The circumstances of minor planet discovery

    International Nuclear Information System (INIS)

    Pilcher, F.

    1989-01-01

    The circumstances of discoveries of minor planets are presented in tabular form. Complete data are given for planets 2125-4044, together with notes pertaining to these planets. Information in the table includes the permanent number; the official name; for planets 330 and forward, the table includes the provisional designation attached to the discovery apparition and the year, month, the day of discovery, and the discovery place

  8. CALIDAD DEL AGUA DE LAS QUEBRADAS LA CRISTALINA Y LA RISARALDA, SAN LUIS, ANTIOQUIA

    Directory of Open Access Journals (Sweden)

    María Cecilia Arango

    2008-07-01

    Full Text Available Las quebradas La Cristalina y La Risaralda son las fuentes que abastecen el acueducto del área urbana del municipio de San Luis, Antioquia. El propósito de este estudio fue elaborar un mapa de calidad de agua que sirva como base de comparación de la evolución de las quebradas y justifique la inversión de los recursos del Municipio en el mejoramiento prioritario de los tramos más críticos. Para establecer la calidad del agua se determinaron indicadores físicos, químicos y biológicos, entre ellos algunas características físicas de las quebradas como tipo de sustrato, cobertura de riberas y hábitats acuáticos, temperatura, conductividad, oxígeno, pH, coliformes y macroinvertebrados acuáticos. A partir de los datos colectados se calcularon los índices BMWP/Col1, ASPT, ETP, índice de dípteros y de equidad. Con los resultados obtenidos del ASPT se construyó el mapa de calidad de agua para ambas quebradas. Las quebradas están bien oxigenadas debido a la turbulencia provocada por la conformación rocosa de su lecho, que a su vez permite la diversidad de macroinvertebrados acuáticos. Sin embargo, algunos tramos de estas corrientes están sometidos a contaminación de origen doméstico y agropecuario, lo cual limita sus condiciones de uso.The streams La Cristalina and La Risaralda are the water sources for the urban area of the Municipality of San Luis, Antioquia. The intention of this study was to develop a map of water quality that serves as base as comparison of the evolution of the streams and allows the high-priority destination of the resources of the Municipality in the improvement of those more critical sections. In order to determine the quality of the water, parameters and some characteristics of the stream that can alter the quality of the water were measured, like substrate of the bed, cover of banks, aquatic habitats, temperature, conductivity, oxygen, pH, coliforms, and aquatic macroinvertebrates. The indices calculated

  9. THE TRAVELLING SALESMAN PROBLEM IN THE ENGINEERING EDUCATION PROGRAMMING CURRICULUM

    Directory of Open Access Journals (Sweden)

    Yevgeny Gayev

    2017-11-01

    Full Text Available Objective: To make students familiar with the famous Traveling Salesman Problem (TSP and suggest the latter to become a common exercise in engineering programming curriculum provided the students master computer science in the easy programming environment MATLAB. Methods: easy programming in MATLAB makes true such modern educational approach as “discovery based” methodology. Results: a MATLAB TSP-program oriented to Ukrainian map is suggested that allows to pictorially demonstrate the process of optimal route search with an option to decelerate or accelerate the demonstration. The program is guessed to be useful both for learning the TSP as one of fundamental logistics problems and as an intriguing programming curriculum excersize. Several sub-programs according to key stone Computer Science Curriculum have also been suggested. This lies in line with recent “discovery based” learning methodology. Discussion: we explain how to create this program for visual discrete optimization, suggest required subprograms belonging to key stone programming algorithms including rather modern graphical user interface (GUI, how to use this MATLAB TSP-program for demonstration the drastical grows of solution time required. Conclusions: easy programming being realized in MATLAB makes dificult curriculum problems attractive to students; it focuses them to main problem’ features, laws and algorithms implementing the “discovery based” methodology in such a way.

  10. Rediscovering Don Swanson: The Past, Present and Future of Literature-based Discovery

    Directory of Open Access Journals (Sweden)

    Neil R. Smalheiser

    2017-12-01

    actually use discovery tools and that these are actually able to help them make experimental discoveries in the lab and in the clinic. Originality/value: This paper discusses problems and issues which were inherent in Don’s thoughts during his life, including those which have not yet been fully taken up and studied systematically.

  11. Toxins and drug discovery.

    Science.gov (United States)

    Harvey, Alan L

    2014-12-15

    Components from venoms have stimulated many drug discovery projects, with some notable successes. These are briefly reviewed, from captopril to ziconotide. However, there have been many more disappointments on the road from toxin discovery to approval of a new medicine. Drug discovery and development is an inherently risky business, and the main causes of failure during development programmes are outlined in order to highlight steps that might be taken to increase the chances of success with toxin-based drug discovery. These include having a clear focus on unmet therapeutic needs, concentrating on targets that are well-validated in terms of their relevance to the disease in question, making use of phenotypic screening rather than molecular-based assays, and working with development partners with the resources required for the long and expensive development process. Copyright © 2014 The Author. Published by Elsevier Ltd.. All rights reserved.

  12. Statistics and Discoveries at the LHC (1/4)

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    The lectures will give an introduction to statistics as applied in particle physics and will provide all the necessary basics for data analysis at the LHC. Special emphasis will be placed on the the problems and questions that arise when searching for new phenomena, including p-values, discovery significance, limit setting procedures, treatment of small signals in the presence of large backgrounds. Specific issues that will be addressed include the advantages and drawbacks of different statistical test procedures (cut-based, likelihood-ratio, etc.), the look-elsewhere effect and treatment of systematic uncertainties.

  13. Statistics and Discoveries at the LHC (3/4)

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    The lectures will give an introduction to statistics as applied in particle physics and will provide all the necessary basics for data analysis at the LHC. Special emphasis will be placed on the the problems and questions that arise when searching for new phenomena, including p-values, discovery significance, limit setting procedures, treatment of small signals in the presence of large backgrounds. Specific issues that will be addressed include the advantages and drawbacks of different statistical test procedures (cut-based, likelihood-ratio, etc.), the look-elsewhere effect and treatment of systematic uncertainties.

  14. Statistics and Discoveries at the LHC (2/4)

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    The lectures will give an introduction to statistics as applied in particle physics and will provide all the necessary basics for data analysis at the LHC. Special emphasis will be placed on the the problems and questions that arise when searching for new phenomena, including p-values, discovery significance, limit setting procedures, treatment of small signals in the presence of large backgrounds. Specific issues that will be addressed include the advantages and drawbacks of different statistical test procedures (cut-based, likelihood-ratio, etc.), the look-elsewhere effect and treatment of systematic uncertainties.

  15. Statistics and Discoveries at the LHC (4/4)

    CERN Multimedia

    CERN. Geneva

    2010-01-01

    The lectures will give an introduction to statistics as applied in particle physics and will provide all the necessary basics for data analysis at the LHC. Special emphasis will be placed on the the problems and questions that arise when searching for new phenomena, including p-values, discovery significance, limit setting procedures, treatment of small signals in the presence of large backgrounds. Specific issues that will be addressed include the advantages and drawbacks of different statistical test procedures (cut-based, likelihood-ratio, etc.), the look-elsewhere effect and treatment of systematic uncertainties.

  16. Testing jumps via false discovery rate control.

    Directory of Open Access Journals (Sweden)

    Yu-Min Yen

    Full Text Available Many recently developed nonparametric jump tests can be viewed as multiple hypothesis testing problems. For such multiple hypothesis tests, it is well known that controlling type I error often makes a large proportion of erroneous rejections, and such situation becomes even worse when the jump occurrence is a rare event. To obtain more reliable results, we aim to control the false discovery rate (FDR, an efficient compound error measure for erroneous rejections in multiple testing problems. We perform the test via the Barndorff-Nielsen and Shephard (BNS test statistic, and control the FDR with the Benjamini and Hochberg (BH procedure. We provide asymptotic results for the FDR control. From simulations, we examine relevant theoretical results and demonstrate the advantages of controlling the FDR. The hybrid approach is then applied to empirical analysis on two benchmark stock indices with high frequency data.

  17. Luis Crespí Jaume, científico de la Junta para Ampliación de Estudios y catedrático de Agricultura del Instituto-Escuela

    Directory of Open Access Journals (Sweden)

    Masip Hidalgo, Carmen

    2011-06-01

    Full Text Available This article about Luis Crespí Jaume (Madrid, 1889- 1963 aims to recall his teaching work as Agriculture Professor at “Madrid Instituto-Escuela” and its stage as scientist linked to “Junta para Ampliación de Estudios “(JAE. This following text focuses on his teaching practice which was based on the analysis of the didactic planning in the field of Agriculture that he developed, the methodology applied, the scientific materials used in the class and laboratory sessions, the class and laboratory students’ notebooks and finally the books that they consulted for their classworks.

    Este artículo sobre Luis Crespí Jaume (Madrid, 1889-1963 pretende recordar su labor pedagógica como catedrático de Agricultura del Instituto-Escuela de Madrid y su etapa como científico vinculado a la Junta para Ampliación de Estudios (JAE. Nuestro comentario sobre su práctica docente se basa en el análisis de la programación de la materia de Agricultura que él mismo elaboró, en la metodología que aplicó, en los materiales científicos utilizados en el aula y en el laboratorio, en los cuadernos de clase y de prácticas de sus alumnos y en los libros que éstos consultaban para sus trabajos.

  18. mHealth Visual Discovery Dashboard.

    Science.gov (United States)

    Fang, Dezhi; Hohman, Fred; Polack, Peter; Sarker, Hillol; Kahng, Minsuk; Sharmin, Moushumi; al'Absi, Mustafa; Chau, Duen Horng

    2017-09-01

    We present Discovery Dashboard, a visual analytics system for exploring large volumes of time series data from mobile medical field studies. Discovery Dashboard offers interactive exploration tools and a data mining motif discovery algorithm to help researchers formulate hypotheses, discover trends and patterns, and ultimately gain a deeper understanding of their data. Discovery Dashboard emphasizes user freedom and flexibility during the data exploration process and enables researchers to do things previously challenging or impossible to do - in the web-browser and in real time. We demonstrate our system visualizing data from a mobile sensor study conducted at the University of Minnesota that included 52 participants who were trying to quit smoking.

  19. La prevención del maltrato al adulto mayor, barrio Paraíso, parroquia José Luis Tamayo, cantón salinas, 2014-2016.

    OpenAIRE

    Martínez Salas, Letty J.

    2017-01-01

    El maltrato constituye un problema social que afecta al desarrollo humano del adulto mayor que habita en el barrio Paraíso de la parroquia José Luis Tamayo, limitando sus libertades y capacidades. El objetivo del presente trabajo consiste en analizar cómo prevenir el maltrato hacia estas personas. La metodología utilizada en este estudio es tipo cualitativo, efectuada a través de la entrevista con actores locales, consultas teóricas y bibliográficas, reportes estadísticos, complementadas con ...

  20. Service discovery at home

    NARCIS (Netherlands)

    Sundramoorthy, V.; Scholten, Johan; Jansen, P.G.; Hartel, Pieter H.

    2003-01-01

    Service discovery is a fairly new field that kicked off since the advent of ubiquitous computing and has been found essential in the making of intelligent networks by implementing automated discovery and remote control between devices. This paper provides an overview and comparison of several

  1. The Greatest Mathematical Discovery?

    Energy Technology Data Exchange (ETDEWEB)

    Bailey, David H.; Borwein, Jonathan M.

    2010-05-12

    What mathematical discovery more than 1500 years ago: (1) Is one of the greatest, if not the greatest, single discovery in the field of mathematics? (2) Involved three subtle ideas that eluded the greatest minds of antiquity, even geniuses such as Archimedes? (3) Was fiercely resisted in Europe for hundreds of years after its discovery? (4) Even today, in historical treatments of mathematics, is often dismissed with scant mention, or else is ascribed to the wrong source? Answer: Our modern system of positional decimal notation with zero, together with the basic arithmetic computational schemes, which were discovered in India about 500 CE.

  2. Open Drug Discovery Toolkit (ODDT): a new open-source player in the drug discovery field.

    Science.gov (United States)

    Wójcikowski, Maciej; Zielenkiewicz, Piotr; Siedlecki, Pawel

    2015-01-01

    There has been huge progress in the open cheminformatics field in both methods and software development. Unfortunately, there has been little effort to unite those methods and software into one package. We here describe the Open Drug Discovery Toolkit (ODDT), which aims to fulfill the need for comprehensive and open source drug discovery software. The Open Drug Discovery Toolkit was developed as a free and open source tool for both computer aided drug discovery (CADD) developers and researchers. ODDT reimplements many state-of-the-art methods, such as machine learning scoring functions (RF-Score and NNScore) and wraps other external software to ease the process of developing CADD pipelines. ODDT is an out-of-the-box solution designed to be easily customizable and extensible. Therefore, users are strongly encouraged to extend it and develop new methods. We here present three use cases for ODDT in common tasks in computer-aided drug discovery. Open Drug Discovery Toolkit is released on a permissive 3-clause BSD license for both academic and industrial use. ODDT's source code, additional examples and documentation are available on GitHub (https://github.com/oddt/oddt).

  3. Circuits and electronics hands-on learning with analog discovery

    CERN Document Server

    Okyere Attia, John

    2018-01-01

    The book provides instructions on building circuits on breadboards, connecting the Analog Discovery wires to the circuit under test, and making electrical measurements. Various measurement techniques are described and used in this book, including: impedance measurements, complex power measurements, frequency response measurements, power spectrum measurements, current versus voltage characteristic measurements of diodes, bipolar junction transistors, and Mosfets. The book includes end-of-chapter problems for additional exercises geared towards hands-on learning, experimentation, comparisons between measured results and those obtained from theoretical calculations.

  4. Knowledge management and Discovery for advanced Enterprise Knowledge Engineering

    OpenAIRE

    Novi, Daniele

    2014-01-01

    2012 - 2013 The research work addresses mainly issues related to the adoption of models, methodologies and knowledge management tools that implement a pervasive use of the latest technologies in the area of Semantic Web for the improvement of business processes and Enterprise 2.0 applications. The first phase of the research has focused on the study and analysis of the state of the art and the problems of Knowledge Discovery database, paying more attention to the data mining systems. Th...

  5. Integrative subtype discovery in glioblastoma using iCluster.

    Directory of Open Access Journals (Sweden)

    Ronglai Shen

    Full Text Available Large-scale cancer genome projects, such as the Cancer Genome Atlas (TCGA project, are comprehensive molecular characterization efforts to accelerate our understanding of cancer biology and the discovery of new therapeutic targets. The accumulating wealth of multidimensional data provides a new paradigm for important research problems including cancer subtype discovery. The current standard approach relies on separate clustering analyses followed by manual integration. Results can be highly data type dependent, restricting the ability to discover new insights from multidimensional data. In this study, we present an integrative subtype analysis of the TCGA glioblastoma (GBM data set. Our analysis revealed new insights through integrated subtype characterization. We found three distinct integrated tumor subtypes. Subtype 1 lacks the classical GBM events of chr 7 gain and chr 10 loss. This subclass is enriched for the G-CIMP phenotype and shows hypermethylation of genes involved in brain development and neuronal differentiation. The tumors in this subclass display a Proneural expression profile. Subtype 2 is characterized by a near complete association with EGFR amplification, overrepresentation of promoter methylation of homeobox and G-protein signaling genes, and a Classical expression profile. Subtype 3 is characterized by NF1 and PTEN alterations and exhibits a Mesenchymal-like expression profile. The data analysis workflow we propose provides a unified and computationally scalable framework to harness the full potential of large-scale integrated cancer genomic data for integrative subtype discovery.

  6. The in silico drug discovery toolbox: applications in lead discovery and optimization.

    Science.gov (United States)

    Bruno, Agostino; Costantino, Gabriele; Sartori, Luca; Radi, Marco

    2017-11-06

    Discovery and development of a new drug is a long lasting and expensive journey that takes around 15 years from starting idea to approval and marketing of new medication. Despite the R&D expenditures have been constantly increasing in the last few years, number of new drugs introduced into market has been steadily declining. This is mainly due to preclinical and clinical safety issues, which still represent about 40% of drug discontinuation. From this point of view, it is clear that if we want to increase drug-discovery success rate and reduce costs associated with development of a new drug, a comprehensive evaluation/prediction of potential safety issues should be conducted as soon as possible during early drug discovery phase. In the present review, we will analyse the early steps of drug-discovery pipeline, describing the sequence of steps from disease selection to lead optimization and focusing on the most common in silico tools used to assess attrition risks and build a mitigation plan. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  7. Offshore geology and geomorphology from Point Piedras Blancas to Pismo Beach, San Luis Obispo County, California

    Science.gov (United States)

    Watt, Janet Tilden; Johnson, Samuel Y.; Hartwell, Stephen R.; Roberts, Michelle

    2015-01-01

    Marine geology and geomorphology were mapped along the continental shelf and upper slope between Point Piedras Blancas and Pismo Beach, California. The map area is divided into the following three (smaller) map areas, listed from north to south: San Simeon, Morro Bay, and Point San Luis. Each smaller map area consists of a geologic map and the corresponding geophysical data that support the geologic mapping. Each geophysical data sheet includes shaded-relief multibeam bathymetry, seismic-reflection-survey tracklines, and residual magnetic anomalies, as well as a smaller version of the geologic map for reference. Offshore geologic units were delineated on the basis of integrated analysis of adjacent onshore geology, seafloor-sediment and rock samples, multibeam bathymetry and backscatter imagery, magnetic data, and high-resolution seismic-reflection profiles. Although the geologic maps are presented here at 1:35,000 scale, map interpretation was conducted at scales of between 1:6,000 and 1:12,000.

  8. Modelo de sedimentación continental para el rift cretácico de la Argentina central: Ejemplo de la sierra de las Quijadas, San Luis

    OpenAIRE

    D. Rivarola; L. Spalletti

    2006-01-01

    En este trabajo se estudian las sedimentitas continentales cretácicas (Grupo del Gigante) en la sierra de las Quijadas, ubicada en el noroeste de la provincia de San Luis. La información se obtuvo mediante el relevamiento de 15 perfiles sedimentológicos de detalle que permitieron definir 21 facies sedimentarias y 12 asociaciones de facies. Las facies permitieron interpretar los principales procesos de acumulación sedimentaria, mientras que a partir de las asociaciones de facies se propusieron...

  9. Academic Drug Discovery Centres

    DEFF Research Database (Denmark)

    Kirkegaard, Henriette Schultz; Valentin, Finn

    2014-01-01

    Academic drug discovery centres (ADDCs) are seen as one of the solutions to fill the innovation gap in early drug discovery, which has proven challenging for previous organisational models. Prior studies of ADDCs have identified the need to analyse them from the angle of their economic...

  10. Service Discovery At Home

    NARCIS (Netherlands)

    Sundramoorthy, V.; Scholten, Johan; Jansen, P.G.; Hartel, Pieter H.

    Service discovery is a fady new field that kicked off since the advent of ubiquitous computing and has been found essential in the making of intelligent networks by implementing automated discovery and remote control between deviies. This paper provides an ovewiew and comparison of several prominent

  11. Some problems of physics of ultrahigh energy cosmic rays

    International Nuclear Information System (INIS)

    Isaev, P.S.

    1999-01-01

    Nearest 15-20 years will be years of flourishing of experimental researches into the energy of cosmic rays at > or ∼ 10 15 eV and of new discoveries in the physics of elementary particles of ultrahigh energies. Unsolved problems of modern physics of ultrahigh energy cosmic rays, which are relevant to the problems of elementary particles physics, are reviewed

  12. „Unsere tägliche Sendung von der Banalität des Bösen“. Der postmoderne Konflikt in Elfriede Jelineks und Luis Buñuels Würgeengel

    Directory of Open Access Journals (Sweden)

    Aline Vennemann

    2011-12-01

    Full Text Available Civilité et barbarie vont de pair. C’est ce que nous suggèrent le cinéaste espagnol Luis Buñuel et la dramaturge autrichienne Elfriede Jelinek dans leurs versions postmodernes de l’Ange exterminateur. En se réclamant de l’allégorie biblique de l’ange mortifère (Todesengel, ils esquissent une société en rupture avec la conception traditionnelle. Ce portrait d’une société que l’on pourrait qualifier de « post-civilisée » invite à repenser, à partir des deux œuvres fictionnelles, le conflit social qui résulte d’une remise en question radicale des normes sociales de l’Occident.Zivilisiertheit und Barbarei bilden einen gemeinsamen Nexus. Dies suggerieren der spanische Regisseur Luis Buñuel und die österreichische Autorin Elfriede Jelinek in ihren postmodernen Fassungen des Würgeengels. Auf die biblische Figur des Todesengels rekurrierend skizzieren sie eine Gesellschaft, die deutlich mit der traditionellen Selbstauffassung bricht. Das Porträt jener Gesellschaft, die man als „post-zivilisiert“ bezeichnen könnte, lädt dazu ein, den sozialen Konflikt, der sich aus der radikalen Infragestellung der westlichen Gesellschaftsnormen ergibt, anhand der zwei fiktionalen Werke zu überdenken.

  13. Caracterización del nivel de información sobre ITS/VIH/sida en adolescentes de la escuela secundaria básica "José Luis Arruñada" Characterization of the information level on sexual transmission infection (STI)/HIV/aids in adolescents of the "José Luis Arruñada" basic secondary school

    OpenAIRE

    Alejandro Fadragas Fernández; Maydelín Valdés Sánchez; Luis Manuel Fernández Machin

    2012-01-01

    Introducción: en Cuba, el Programa Nacional de Prevención y Control de las Infecciones de Transmisión Sexual y el VIH/sida, se inició desde 1986, con el objetivo fundamental de evitar que el proceso de la infección-enfermedad, se convirtiera en un importante problema de salud para la población cubana. Objetivo: caracterizar el nivel de información que sobre las ITS/VIH/sida, tienen los adolescentes que pertenecen a la escuela secundaria básica "José Luis Arruñada", correspondiente al municipi...

  14. Evolución metamórfica de los gabros coroníticos de El Arenal, faja máfica-ultramáfica El Destino-Las Águilas, sierra de San Luis Metamorphic evolution of the coronitic gabbrons of the El Arenal, El Destino-Las Aguilas, mafic-ultramafic belt, Sierra de San Luis

    OpenAIRE

    N. Brogioni; G. Cruciani; M. Franceschelli; O. Vaselli

    2007-01-01

    Las meta-melagabronoritas coroníticas se localizan en uno de los cuerpos de El Arenal, pertenecientes a la faja máfica-ultramáfica El Destino-Las Aguilas del flanco oriental de la sierra de San Luis. Son rocas de grano fino y representan fraccionados poco evolucionados, con alto contenido de Cr-Ni y [Mg/Mg+FeT++] comprendidas entre 0,72 y 0,75, derivados de un magma toleítico olivínico de bajo Ti, cuyo emplazamiento precedió a la deformación penetrativa y metamorfismo famatinianos. Las microe...

  15. Synthetic biology of antimicrobial discovery.

    Science.gov (United States)

    Zakeri, Bijan; Lu, Timothy K

    2013-07-19

    Antibiotic discovery has a storied history. From the discovery of penicillin by Sir Alexander Fleming to the relentless quest for antibiotics by Selman Waksman, the stories have become like folklore used to inspire future generations of scientists. However, recent discovery pipelines have run dry at a time when multidrug-resistant pathogens are on the rise. Nature has proven to be a valuable reservoir of antimicrobial agents, which are primarily produced by modularized biochemical pathways. Such modularization is well suited to remodeling by an interdisciplinary approach that spans science and engineering. Herein, we discuss the biological engineering of small molecules, peptides, and non-traditional antimicrobials and provide an overview of the growing applicability of synthetic biology to antimicrobials discovery.

  16. El saxofón en la ópera de Luis de Pablo: La señorita Cristina

    Directory of Open Access Journals (Sweden)

    Martínez García, Francisco

    2015-12-01

    Full Text Available At 82 years we will not mention the importance and influence of Luis de Pablo in the musical history of Spain in the last fifty years, but it was not what caught my attention for a PhD thesis on his music, but the the large number of works including saxophone in his catalog: 25 works upon today. It is a very high number compared to what Europeans frontline composers have produced during the twentieth century and the first decade of the 21st. From all this great production, surely excel his operas, as three of his five works dedicated to this genre, the saxophone is present and also with dramatic character roles. Then we will make an analysis of the opera La señorita Cristina, and the employment of the saxophone there, with musical contributions that eleven years after its release are certainly innovative and interesting.A sus 82 años no vamos a citar la importancia e influencia de Luis de Pablo en la historia musical de España en los últimos cincuenta años, pero no fue esto lo que me llamó la atención para realizar una tesis doctoral sobre su música1, sino la gran producción de obras con saxofón dentro de su catálogo: veinticinco obras al momento de hoy. Es un número muy alto comparándolo con lo que los compositores europeos de primera línea han llevado a cabo durante el siglo XX y primera década del XXI. De toda esta gran producción, destacan sin duda sus óperas, ya que en tres de sus cinco obras de este apartado, el saxofón está presente y además con funciones de personaje dramático. A continuación vamos a efectuar un análisis de la ópera La señorita Cristina y del empleo del saxofón en la misma, con unas aportaciones musicales que once años después de su estreno son sin duda novedosas y muy interesantes.

  17. Estudio descriptivo de la percepción de la relación psicotearpeútica en pacientes de la ciudad de San Luis (Descriptive Study of the Perception of the Perception of the Psychotherapeutic Relationship in Patients from the City of San Luis

    Directory of Open Access Journals (Sweden)

    Horacio Daniel García

    2015-06-01

    Full Text Available RESUMEN: Para indagar la percepción del paciente de la relación terapéutica y las valoraciones acerca del terapeuta que podrían ser facilitadoras, se diseñó un estudio recurriendo a una muestra no probabilística compuesta por 108 pacientes (M = 31.90, DE = 11.54, residentes en San Luis, Argentina. Se utilizó el Helping Alliance Questionnaire - HAq-II (Luborsky et al., 1996 y un cuestionario construido ad hoc. En los resultados se observa, en general, una adecuada relación terapéutica y una alta valoración en los terapeutas de aspectos como calidez, seriedad, comprensión, confianza, respeto, interés y compromiso. Las terapeutas mujeres obtuvieron puntuaciones mayores en calidez y seriedad, clima de confianza, compromiso de trabajo, entre otros. Los pacientes sin conocimiento de los diferentes enfoques de psicoterapia tienden a valorar más positivamente aspectos vinculares de la relación terapéutica; en tanto quienes tienen conocimiento poseen expectativas más altas respecto a los resultados que pretenden alcanzar. ABSTRACT: To investigate the patient’s perception of the therapeutic relationship and assessments about the therapist which could be facilitating, we designed a study using a non-probabilistic sample composed by 108 patients (M = 31.90, SD = 11.54, residents in San Luis, Argentina. The Helping Alliance Questionnaire - HAq-II was used (Luborsky et al., 1996 and a questionnaire built ad hoc, too. In general, the results show an appropriate therapeutic relationship and a high rating of therapist aspects such as warmth, seriousness, understanding, trust, respect, interest and commitment. Women therapists obtained higher scores in warmth and seriousness, trust, commitment to work, among others. Patients without knowledge of the different psychotherapy approaches tend to assess more positively relational aspects of the therapeutic relationship; meanwhile those who have knowledge have higher expectations about the results

  18. Corporalidad, espacio y nuevas formas de socialidad en la cinematografía de Luis Ortega

    Directory of Open Access Journals (Sweden)

    Esteban Marcos Dipaola

    2010-08-01

    Full Text Available El artículo analiza la dimensión visual de la corporalidad tal como aparece en las estéticas, las narrativas y las imágenes de los films de Luis Ortega, Caja negra y Monobloc. Partiendo de esa exposición de la corporalidad y también de los gestos y los afectos, se busca analizar la conformación de un espacio social íntimo y cotidiano que en la cinematografía de Ortega se hace presente con la figura de los micromundos, para comprender las nuevas formas de socialidad y la nueva expresión de la experiencia social, ahora dada en la materialidad de los cuerpos como formas de vinculación. Así, las relaciones entre cuerpo y vida o entre cuerpo y dolor se conjugan en el artículo como formas de pensar las condiciones de una nueva experiencia social y cultural. Fecha de recepción: 19 de febrero de 2010. Fecha de aceptación: 14 de julio de 2010.

  19. The discovery of radioactivity: the centenary

    International Nuclear Information System (INIS)

    Patil, S.K.

    1995-01-01

    In the last decade of the nineteenth century, a number of fundamental discoveries of outstanding importance were made unexpectedly which marked the beginning of a new era in physics. A cascade of spectacular discoveries began with the announcement of the discovery of x-rays by Roentgen followed by the discoveries, in quick succession, of radioactivity by Becquerel, of Zeeman effect, of electron by J.J. Thomson, and of polonium and radium by the Curies. Both x-rays and radioactivity have wide applications in scientific, medical and industrial fields and have made outstanding contribution to the advancement of human knowledge and welfare. Radioactivity is well known and no other discovery in the field of physics or chemistry has had a more profound effect on our fundamental knowledge of nature. Present article, on the occasion of the centenary of the discovery of radioactivity, makes an attempt to describe some glimpses of the history of radioactivity. (author). 59 refs

  20. The π discovery

    International Nuclear Information System (INIS)

    Fowler, P.H.

    1988-01-01

    The paper traces the discovery of the Π meson. The discovery was made by exposure of nuclear emulsions to cosmic radiation at high altitudes, with subsequent scanning of the emulsions for meson tracks. Disintegration of nuclei by a negative meson, and the decay of a Π meson were both observed. Further measurements revealed the mass of the meson. The studies carried out on the origin of the Π-mesons, and their mode of decay, are both described. (U.K.)

  1. Epidemiological profile of leprosy in municipality of Sao Luis - Ma from 2006 to 2010

    Directory of Open Access Journals (Sweden)

    Líndia Kalliana da Costa Araújo Alves Carvalho

    2014-02-01

    Full Text Available Objetivo: Analisar o perfil epidemiológico da Hanseníase em São Luís - MA no período de 2006 a 2010. Método: Trata-se de um estudo descritivo, exploratório, quantitativo de casos de hanseníase no município de São Luis- MA, em 2006 a 2010. Os dados foram coletados no Departamento de Informática do Sistema Único de Saúde (DATASUS. Foram coletadas as informações: taxa de incidência, classificação operacional, faixa etária e forma clínica. Resultados: O presente estudo demonstrou altas taxas de incidência sendo a mais alta em 2006. A forma multibacilar foi a mais diagnosticada com ápice em 2009, quanto a faixa etária predominou os maiores de 15 anos. As formas clínicas predominantes foram a dimorfa e a tuberculóide. Conclusão: Os profissionais de saúde devem conhecer medidas profiláticas, avaliação e tratamento para evitar que esses números continuem crescendo e evitar assim incapacidades físicas.

  2. Advancing Drug Discovery through Enhanced Free Energy Calculations.

    Science.gov (United States)

    Abel, Robert; Wang, Lingle; Harder, Edward D; Berne, B J; Friesner, Richard A

    2017-07-18

    A principal goal of drug discovery project is to design molecules that can tightly and selectively bind to the target protein receptor. Accurate prediction of protein-ligand binding free energies is therefore of central importance in computational chemistry and computer aided drug design. Multiple recent improvements in computing power, classical force field accuracy, enhanced sampling methods, and simulation setup have enabled accurate and reliable calculations of protein-ligands binding free energies, and position free energy calculations to play a guiding role in small molecule drug discovery. In this Account, we outline the relevant methodological advances, including the REST2 (Replica Exchange with Solute Temperting) enhanced sampling, the incorporation of REST2 sampling with convential FEP (Free Energy Perturbation) through FEP/REST, the OPLS3 force field, and the advanced simulation setup that constitute our FEP+ approach, followed by the presentation of extensive comparisons with experiment, demonstrating sufficient accuracy in potency prediction (better than 1 kcal/mol) to substantially impact lead optimization campaigns. The limitations of the current FEP+ implementation and best practices in drug discovery applications are also discussed followed by the future methodology development plans to address those limitations. We then report results from a recent drug discovery project, in which several thousand FEP+ calculations were successfully deployed to simultaneously optimize potency, selectivity, and solubility, illustrating the power of the approach to solve challenging drug design problems. The capabilities of free energy calculations to accurately predict potency and selectivity have led to the advance of ongoing drug discovery projects, in challenging situations where alternative approaches would have great difficulties. The ability to effectively carry out projects evaluating tens of thousands, or hundreds of thousands, of proposed drug candidates

  3. Maps of the Bonsall area of the San Luis Rey River valley, San Diego County, California, showing geology, hydrology, and ground-water quality

    Science.gov (United States)

    Izbicki, John A.

    1985-01-01

    In November 1984, 84 wells and 1 spring in the Bonsall area of the San Luis Rey River valley were inventoried by U.S. Geological Survey personnel. Depth to water in 38 wells ranged from 1.3 to 38 ft and 23 wells had depths to water less than 10 feet. Dissolved solids concentration of water from 29 wells and 1 spring sampled in autumn 1983 and spring 1984 ranged from 574 to 2,370 mgs/L. Groundwater with a dissolved solids concentration less than 1,000 mgs/L was generally restricted to the eastern part of the aquifer. The total volume of alluvial fill in the Bonsall area is 113,000 acre-feet; the amount of groundwater storage available in the alluvial aquifer is 18,000 acre-feet. The alluvial aquifer is, in part, surrounded and underlain by colluvium and weathered crystalline rock that add some additional groundwater storage capacity to the system. Data in this report are presented on five maps showing well locations , thickness of alluvial fill, water level contours in November 1983 and hydrographs of selected wells, groundwater quality in spring 1960 and graphs showing changes in dissolved solids concentrations of water from selected wells with time, and groundwater quality in spring 1984. This report is part of a larger cooperative project between the Rainbow Municipal Irrigation District and the U.S. Geological Survey. The purpose of the larger project is to develop an appropriate groundwater management plan for the Bonsall area of the San Luis Rey River valley. (USGS)

  4. Synthetic biology of antimicrobial discovery

    Science.gov (United States)

    Zakeri, Bijan; Lu, Timothy K.

    2012-01-01

    Antibiotic discovery has a storied history. From the discovery of penicillin by Sir Alexander Fleming to the relentless quest for antibiotics by Selman Waksman, the stories have become like folklore, used to inspire future generations of scientists. However, recent discovery pipelines have run dry at a time when multidrug resistant pathogens are on the rise. Nature has proven to be a valuable reservoir of antimicrobial agents, which are primarily produced by modularized biochemical pathways. Such modularization is well suited to remodeling by an interdisciplinary approach that spans science and engineering. Herein, we discuss the biological engineering of small molecules, peptides, and non-traditional antimicrobials and provide an overview of the growing applicability of synthetic biology to antimicrobials discovery. PMID:23654251

  5. 'The Lusiads', poem of discovery

    Directory of Open Access Journals (Sweden)

    Natasha Furlan Felizi

    2016-07-01

    Full Text Available The article proposes reading Os Lusíadas as a discovery journey. Discovery here read as aletheia or “revelation”, as proposed by Sophia de Mello Brey­ner Andresen in 1980. Using Martin Heidegger’s notion of aletheia in the book Parmenides along with Jorge de Sena and Sophia de Mello Breyner Andresen reflections on Camões, I’ll seek to point out alternative readings for Os Lusíadas as a “discovery journey”.

  6. Computational methods in drug discovery

    OpenAIRE

    Sumudu P. Leelananda; Steffen Lindert

    2016-01-01

    The process for drug discovery and development is challenging, time consuming and expensive. Computer-aided drug discovery (CADD) tools can act as a virtual shortcut, assisting in the expedition of this long process and potentially reducing the cost of research and development. Today CADD has become an effective and indispensable tool in therapeutic development. The human genome project has made available a substantial amount of sequence data that can be used in various drug discovery project...

  7. Choosing Discovery: A Literature Review on the Selection and Evaluation of Discovery Layers

    Science.gov (United States)

    Moore, Kate B.; Greene, Courtney

    2012-01-01

    Within the next few years, traditional online public access catalogs will be replaced by more robust and interconnected discovery layers that can serve as primary public interfaces to simultaneously search many separate collections of resources. Librarians have envisioned this type of discovery tool since the 1980s, and research shows that…

  8. Investigations into Library Web-Scale Discovery Services

    Directory of Open Access Journals (Sweden)

    Jason Vaughan

    2008-03-01

    Full Text Available Web-scale discovery services for libraries provide deep discovery to a library’s local and licensed content, and represent an evolution, perhaps a revolution, for end user information discovery as pertains to library collections.  This article frames the topic of web-scale discovery, and begins by illuminating web-scale discovery from an academic library’s perspective – that is, the internal perspective seeking widespread staff participation in the discovery conversation.  This included the creation of a discovery task force, a group which educated library staff, conducted internal staff surveys, and gathered observations from early adopters.  The article next addresses the substantial research conducted with library vendors which have developed these services.  Such work included drafting of multiple comprehensive question lists distributed to the vendors, onsite vendor visits, and continual tracking of service enhancements.  Together, feedback gained from library staff, insights arrived at by the Discovery Task Force, and information gathered from vendors collectively informed the recommendation of a service for the UNLV Libraries.

  9. The Europa Ocean Discovery mission

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, B.C. [Los Alamos National Lab., NM (United States); Chyba, C.F. [Univ. of Arizona, Tucson, AZ (United States); Abshire, J.B. [National Aeronautics and Space Administration, Greenbelt, MD (United States). Goddard Space Flight Center] [and others

    1997-06-01

    Since it was first proposed that tidal heating of Europa by Jupiter might lead to liquid water oceans below Europa`s ice cover, there has been speculation over the possible exobiological implications of such an ocean. Liquid water is the essential ingredient for life as it is known, and the existence of a second water ocean in the Solar System would be of paramount importance for seeking the origin and existence of life beyond Earth. The authors present here a Discovery-class mission concept (Europa Ocean Discovery) to determine the existence of a liquid water ocean on Europa and to characterize Europa`s surface structure. The technical goal of the Europa Ocean Discovery mission is to study Europa with an orbiting spacecraft. This goal is challenging but entirely feasible within the Discovery envelope. There are four key challenges: entering Europan orbit, generating power, surviving long enough in the radiation environment to return valuable science, and complete the mission within the Discovery program`s launch vehicle and budget constraints. The authors will present here a viable mission that meets these challenges.

  10. 29 CFR 18.13 - Discovery methods.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 1 2010-07-01 2010-07-01 true Discovery methods. 18.13 Section 18.13 Labor Office of the... ADMINISTRATIVE LAW JUDGES General § 18.13 Discovery methods. Parties may obtain discovery by one or more of the following methods: Depositions upon oral examination or written questions; written interrogatories...

  11. Em torno de Michel Foucault e Luis Buñuel: saber e poder na análise de O Discreto Charme da Burguesia

    OpenAIRE

    Priscila Canova Motta

    2014-01-01

    O objetivo desta pesquisa é analisar o filme O Discreto Charme da Burguesia, de Luis Buñuel (1972), por meio de alguns conceitos do referencial teórico-metodológico de Michel Foucault: saber e enunciado discursivo em suas relações com o poder e verdade, e buscar compreender o poder em seu exercício no filme, e não apenas em seus efeitos. Partindo de alguns princípios sobre saber em Foucault, mapeamos um enunciado fílmico que apareceu em algumas sequências, qual seja: O barulho que oculta a di...

  12. Geo-Enrichment and Semantic Enhancement of Metadata Sets to Augment Discovery in Geoportals

    Directory of Open Access Journals (Sweden)

    Bernhard Vockner

    2014-03-01

    Full Text Available Geoportals are established to function as main gateways to find, evaluate, and start “using” geographic information. Still, current geoportal implementations face problems in optimizing the discovery process due to semantic heterogeneity issues, which leads to low recall and low precision in performing text-based searches. Therefore, we propose an enhanced semantic discovery approach that supports multilingualism and information domain context. Thus, we present workflow that enriches existing structured metadata with synonyms, toponyms, and translated terms derived from user-defined keywords based on multilingual thesauri and ontologies. To make the results easier and understandable, we also provide automated translation capabilities for the resource metadata to support the user in conceiving the thematic content of the descriptive metadata, even if it has been documented using a language the user is not familiar with. In addition, to text-enable spatial filtering capabilities, we add additional location name keywords to metadata sets. These are based on the existing bounding box and shall tweak discovery scores when performing single text line queries. In order to improve the user’s search experience, we tailor faceted search strategies presenting an enhanced query interface for geo-metadata discovery that are transparently leveraging the underlying thesauri and ontologies.

  13. Biodiversity and systematics in cephalopods: Unresolved problems ...

    African Journals Online (AJOL)

    Some problems of cephalopod biodiversity are discussed. Many squid species are represented by 2–4 intraspecies groupings that may be wholly or partly sympatric, but differ in spawning season and size at maturity. They may be genetically distinct stock units, but their taxonomic status remains unresolved. Discovery of a ...

  14. Secure neighborhood discovery: A fundamental element for mobile ad hoc networking

    DEFF Research Database (Denmark)

    Papadimitratos, P.; Poturalski, M.; Schaller, P.

    2008-01-01

    Pervasive computing systems will likely be deployed in the near future, with the proliferation of wireless devices and the emergence of ad hoc networking as key enablers. Coping with mobility and the volatility of wireless communications in such systems is critical. Neighborhood discovery (ND......) - the discovery of devices directly reachable for communication or in physical proximity - becomes a fundamental requirement and building block for various applications. However, the very nature of wireless mobile networks makes it easy to abuse ND and thereby compromise the overlying protocols and applications....... Thus, providing methods to mitigate this vulnerability and secure ND is crucial. In this article we focus on this problem and provide definitions of neighborhood types and ND protocol properties, as well as a broad classification of attacks. Our ND literature survey reveals that securing ND is indeed...

  15. The Spiral Discovery Network as an Automated General-Purpose Optimization Tool

    Directory of Open Access Journals (Sweden)

    Adam B. Csapo

    2018-01-01

    Full Text Available The Spiral Discovery Method (SDM was originally proposed as a cognitive artifact for dealing with black-box models that are dependent on multiple inputs with nonlinear and/or multiplicative interaction effects. Besides directly helping to identify functional patterns in such systems, SDM also simplifies their control through its characteristic spiral structure. In this paper, a neural network-based formulation of SDM is proposed together with a set of automatic update rules that makes it suitable for both semiautomated and automated forms of optimization. The behavior of the generalized SDM model, referred to as the Spiral Discovery Network (SDN, and its applicability to nondifferentiable nonconvex optimization problems are elucidated through simulation. Based on the simulation, the case is made that its applicability would be worth investigating in all areas where the default approach of gradient-based backpropagation is used today.

  16. 41 CFR 60-30.33 - Discovery.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Discovery. 60-30.33... 11246 Expedited Hearing Procedures § 60-30.33 Discovery. (a) Any party may serve requests for admissions... with § 60-30.8, the Administrative Law Judge may allow the taking of depositions. Other discovery will...

  17. LUIS PUELLES ROMERO. Honoré Daumier. La risa republicana. Madrid: Adaba Editores, 2014, 427 págs., 154 ils.

    Directory of Open Access Journals (Sweden)

    Miguel Ángel Gamonal Torres

    2016-07-01

    Full Text Available Hacer una aportación significativa al conocimiento de Daumier, su obra y su época, es una tarea que Luis Puelles, Profesor de Estética y Teoría de las Artes de la Universidad de Málaga, cumple de manera muy satisfactoria, sobre todo para el lector interesado que encuentra un sobresaliente ensayo en español, construido sobre la muy abundante literatura crítica e histórico-artística existente sobre el artista francés, pero también sobre el brillante dominio que el autor muestra de un sinfín de cuestiones y enfoques de índole estético-filosófico, aunque también sociológico, crítico-literario, etc. …

  18. Antibody informatics for drug discovery

    DEFF Research Database (Denmark)

    Shirai, Hiroki; Prades, Catherine; Vita, Randi

    2014-01-01

    to the antibody science in every project in antibody drug discovery. Recent experimental technologies allow for the rapid generation of large-scale data on antibody sequences, affinity, potency, structures, and biological functions; this should accelerate drug discovery research. Therefore, a robust bioinformatic...... infrastructure for these large data sets has become necessary. In this article, we first identify and discuss the typical obstacles faced during the antibody drug discovery process. We then summarize the current status of three sub-fields of antibody informatics as follows: (i) recent progress in technologies...... for antibody rational design using computational approaches to affinity and stability improvement, as well as ab-initio and homology-based antibody modeling; (ii) resources for antibody sequences, structures, and immune epitopes and open drug discovery resources for development of antibody drugs; and (iii...

  19. Data Warehouse Discovery Framework: The Foundation

    Science.gov (United States)

    Apanowicz, Cas

    The cost of building an Enterprise Data Warehouse Environment runs usually in millions of dollars and takes years to complete. The cost, as big as it is, is not the primary problem for a given corporation. The risk that all money allocated for planning, design and implementation of the Data Warehouse and Business Intelligence Environment may not bring the result expected, fare out way the cost of entire effort [2,10]. The combination of the two above factors is the main reason that Data Warehouse/Business Intelligence is often single most expensive and most risky IT endeavor for companies [13]. That situation was the main author's inspiration behind founding of Infobright Corp and later on the concept of Data Warehouse Discovery Framework.

  20. 45 CFR 213.23a - Discovery.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 2 2010-10-01 2010-10-01 false Discovery. 213.23a Section 213.23a Public Welfare... Discovery. The Department and any party named in the notice issued pursuant to § 213.11 shall have the right to conduct discovery (including depositions) against opposing parties. Rules 26-37 of the Federal...

  1. Et certe opera Deus facit mediantibus causis secundis”: fray Luis de León y la determinación del derecho

    Directory of Open Access Journals (Sweden)

    Sebastián Contreras Aguirre

    2014-06-01

    Full Text Available Luis de León is one of the most important figures of so called Scholastic of Salamanca. In his work, that is the culmination of the Augustinian school of the sixteenth century, are present the most different activities (jurist, prose writer, theologian, poet, etc. and the most different schools of thought (Thomism, Nominalism, Humanism, etc.. The legal philosophy of León, which is what interests us now, has been apparently overshadowed by his reputation as a writer and mystic. But this does not make his work as jurist in not valuable. On the contrary, the legal ideas of Spanish thinker represent one of principal pieces of Theological School of Salamanca

  2. Comunidades de roedores nocturnos en un ecotono de matorrales micrófilos y zacatal gipsófilo en San Luis Potosí, México Nocturnal rodents at the edge of a microphyllous shrubland and gypsophilous grassland in San Luis Potosi, Mexico

    Directory of Open Access Journals (Sweden)

    Jaime Luévano

    2008-06-01

    Full Text Available En el presente estudio se compara la abundancia y riqueza entre los roedores nocturnos de un zacatal gipsófilo y los de 3 matorrales micrófilos, en el norte de San Luis Potosí. Los muestreos se llevaron a cabo en sitios con distintas características edáficas y de estructura de la vegetación, en la estación lluviosa y en la seca de los años 2003 y 2004. Como estimador del tamaño poblacional se utilizó el número de individuos capturados en cada periodo. Se capturaron 414 individuos de 12 especies de las familias Heteromyidae y Muridae. Se concluye que: 1 las comunidades de roedores en cada sitio fueron diferentes en función de la estructura vegetal y cambiaron de manera notable entre el zacatal y los 3 sitios de matorral adyacentes; 2 dichas comunidades reflejaron el mosaico de la vegetación más que la época del año; 3 los tres tipos de matorral mantuvieron su identidad individual a lo largo del año, y 4 la baja precipitación y/o el pastoreo, a través de la reducción de la cobertura vegetal sobre suelos gipsófilos afectó a los roedores.In this study we compared abundance and species richness of nocturnal rodents at the edge of gypsophilous grassland on an exposed gypsum substrate and 3 sites of microphilous shrubland, in northern San Luis Potosí, Mexico. We sampled at sites that differed in edaphic characteristics and vegetation structure, in the wet and dry seasons of 2003 and 2004. As a population estimator we used the number of individuals captured in each sampling period. We captured 414 individuals of 12 species of Heteromyidae and Muridae. We concluded that 1 rodent communities were different among sites as a function of vegetation structure, and varied notably between grassland and adjacent shrublands: 2 such communities reflected the vegetation mosaic more than season of the year: 3 the three shrubland types maintained their identity throughout the year; y 4 low precipitation and/or grazing, through the reduction of

  3. Drive Cost Reduction, Increase Innovation and Mitigate Risk with Advanced Knowledge Discovery Tools Designed to Unlock and Leverage Prior Knowledge

    International Nuclear Information System (INIS)

    Mitchell, I.

    2016-01-01

    Full text: The nuclear industry is knowledge-intensive and includes a diverse number of stakeholders. Much of this knowledge is at risk as engineers, technicians and project professionals retire, leaving a widening skills and information gap. This knowledge is critical in an increasingly complex environment with information from past projects often buried in decades-old, non-integrated systems enterprise. Engineers can spend 40% or more of their time searching for answers across the enterprise instead of solving problems. The inability to access trusted industry knowledge results in increased risk and expense. Advanced knowledge discovery technologies slash research times by as much as 75% and accelerate innovation and problem solving by giving technical professionals access to the information they need, in the context of the problems they are trying to solve. Unlike traditional knowledge management approaches, knowledge discovery tools powered by semantic search technologies are adept at uncovering answers in unstructured data and require no tagging, organization or moving of data, meaning a smaller IT footprint and faster time-to-knowledge. This session will highlight best-in-class knowledge discovery technologies, content, and strategies to give nuclear industry organizations the ability to leverage the corpus of enterprise knowledge into the future. (author

  4. Yeast surface display platform for rapid discovery of conformationally selective nanobodies

    DEFF Research Database (Denmark)

    McMahon, Conor; Baier, Alexander S.; Pascolutti, Roberta

    2018-01-01

    this problem, we report a fully in vitro platform for nanobody discovery based on yeast surface display. We provide a blueprint for identifying nanobodies, demonstrate the utility of the library by crystallizing a nanobody with its antigen, and most importantly, we utilize the platform to discover...... conformationally selective nanobodies to two distinct human GPCRs. To facilitate broad deployment of this platform, the library and associated protocols are freely available for nonprofit research....

  5. Intelligent Content Discovery on the Mobile Internet: Experiences and Lessons Learned

    OpenAIRE

    Smyth, Barry; Cotter, Paul; Oman, Stephen

    2008-01-01

    The mobile Internet represents a massive opportunity for mobile operators and content providers. Today there are more than 2 billion mobile subscribers, with 3 billion predicted by the end of 2007. However, despite significant improvements in handsets, infrastructure, content, and charging models, mobile users are still struggling to access and locate relevant content and services. An important part of this so-called content-discovery problem relates to the navigation effort that users must i...

  6. Perception of the general population in Ciudad Valles, San Luis Potosi regarding waste production in hairdressing salons

    Directory of Open Access Journals (Sweden)

    Juan José Maldonado-Miranda

    2016-02-01

    Full Text Available Hairdressing salons offer a wide range of services including treatments for hair and skin. However, these activities result in the production of residues that are improperly discharged into drainage, generating a negative impact on the environment. This study provides results of a first stage in a project regarding the analysis of waste disposal in hairdressing salons in the municipality of Ciudad Valles, San Luis Potosi, Mexico. Information gathering was conducted through a field work study by surveys given to workers in hairdressing salons in Ciudad Valles. The information presented in this study indicates that in hairdressing salons in Ciudad Valles there is no management plan for the management of waste that could be severely impacting the environment. The information presented here will be the basis for identifying priority areas for intervention, developing new research projects and setting new environmental policies. In addition, the results presented here can be extrapolated to many rural and urban areas all over Mexico.

  7. Los rasgos de la lírica del exilio en la poética de Luis Cernuda

    Directory of Open Access Journals (Sweden)

    Ana Martínez García

    2015-01-01

    Full Text Available La obra literaria creada en el destierro por los españoles tuvo ciertos caracteres esenciales que le llevan a formar parte de una tendencia distinta, a no ligarse a los movimientos literarios coetáneos que se manifestaban en la península. La lírica fue el género más influenciado por la situación que los exiliados estaban experimentando, razón por la que sus textos pueden dividirse en periodos, con diferentes rasgos, dependientes de la situación histórica que experimentaban: Segunda Guerra Mundial, final de la guerra y afianzamiento del Franquismo, etc. Entre los muchos autores exiliados, Luis Cernuda fue uno de los más reconocidos, donde los rasgos de la poética del destierro estaban presentes, de una forma velada, trágica y sucinta, como era propio de toda su producción.

  8. Dual electricity generation biogas-diesel in the community of Maguey, municipality of San Luis. Santiago de Cuba

    International Nuclear Information System (INIS)

    Recio Recio, Angel Amado; Palacios Barrera, Antonio; Salas Diaz, Alberto; Bertot, Romulo; Garcia Faure, Luis

    2009-01-01

    The work was developed in the rural community Magueyal, Popular Council Chamarreta of the Municipality San Luis, Santiago de Cuba province, consisting of 198 inhabitants, distributed in 75 of these 64 homes have electricity, also has a primary school and a medical clinic family. Its main activity is livestock to be located in a place where the topography is very steep, leading to not develop infrastructure networks. The electricity was supplied by diesel engine MWM-DITER, Type: D 327-2 and the supply of electricity was only 4 hours a day; it was decided to take him to eight hours using biogas, thus saving fuel. For this purposes and with funding from an international project proceeded to construction of two biogas digesters 83.04 m3 and 91.26 m3 of total volume, respectively, with which the generator feeds two reducing diesel consumption by 75% and increasing the hours of supply electricity for 4-8 hours. (author)

  9. Estimation of uranium resources by life-cycle or discovery-rate models: a critique

    International Nuclear Information System (INIS)

    Harris, D.P.

    1976-10-01

    This report was motivated primarily by M. A. Lieberman's ''United States Uranium Resources: An Analysis of Historical Data'' (Science, April 30). His conclusion that only 87,000 tons of U 3 O 8 resources recoverable at a forward cost of $8/lb remain to be discovered is criticized. It is shown that there is no theoretical basis for selecting the exponential or any other function for the discovery rate. Some of the economic (productivity, inflation) and data issues involved in the analysis of undiscovered, recoverable U 3 O 8 resources on discovery rates of $8 reserves are discussed. The problem of the ratio of undiscovered $30 resources to undiscovered $8 resources is considered. It is concluded that: all methods for the estimation of unknown resources must employ a model of some form of the endowment-exploration-production complex, but every model is a simplification of the real world, and every estimate is intrinsically uncertain. The life-cycle model is useless for the appraisal of undiscovered, recoverable U 3 O 8 , and the discovery rate model underestimates these resources

  10. Syntactically Silent Subjects: Luis Muñoz and the Poetry of Ellipsis

    Directory of Open Access Journals (Sweden)

    Judith Nantell

    2012-06-01

    Full Text Available Luis Muñoz (1966 is one of contemporary Spain’s most salient poets. His work has been described as demonstrating a discourse of ellipsis; yet no study has examined in detail his masterful use of syntactic and figurative omission. In fact, even though Muñoz’s published collections to date span two centuries, no single study has been devoted to his decidedly innovative expressivity. His work has been commented on in various panoramic essays considering contemporary poetry published in Spain at this temporal intersection and a number of his poems have been gathered into noteworthy anthologies of this same era. His poetry has been nominated for prestigious awards in Spain and in 2001 Correspondencias ‘Correspondences’ received the fourth Premio Internacional de Poesía del 27 as well as the Premio de Ojo Crítico de Poesía . The present study examines Muñoz’s most recent Querido silencio (2006 ‘Dear Silence’ where ellipsis figures prominently as the poet maximizes and exploits conceptual and linguistic efficiency. In one exemplary poem, “Dejar la poesía” ‘Leave Poetry,’ two syntactically silent subjects engage in an innovative conversation concerning the nature of poetry. At the same time this intriguing dialogue also offers a unique response to the essential question framing this poem and the collection as a whole: Why is poetry an addiction?

  11. Discovery of massive neutral vector mesons

    International Nuclear Information System (INIS)

    Anon.

    1976-01-01

    Personal accounts of the discovery of massive neutral vector mesons (psi particles) are given by researchers S. Ting, G. Goldhaber, and B. Richter. The double-arm spectrometer and the Cherenkov effect are explained in a technical note, and the solenoidal magnetic detector is discussed in an explanatory note for nonspecialists. Reprints of three papers in Physical Review Letters which announced the discovery of the particles are given: Experimental observation of a heavy particle J, Discovery of a narrow resonance in e + e - annihilation, and Discovery of a second narrow resonance in e + e - annihilation. A discussion of subsequent developments and scientific biographies of the three authors are also presented. 25 figures

  12. Functional principles of registry-based service discovery

    NARCIS (Netherlands)

    Sundramoorthy, V.; Tan, C.; Hartel, P.H.; Hartog, den J.I.; Scholten, J.

    2005-01-01

    As Service Discovery Protocols (SDP) are becoming increasingly important for ubiquitous computing, they must behave according to predefined principles. We present the functional Principles of Service Discovery for robust, registry-based service discovery. A methodology to guarantee adherence to

  13. Materials Discovery | Materials Science | NREL

    Science.gov (United States)

    Discovery Materials Discovery Images of red and yellow particles NREL's research in materials characterization of sample by incoming beam and measuring outgoing particles, with data being stored and analyzed Staff Scientist Dr. Zakutayev specializes in design of novel semiconductor materials for energy

  14. On the pulse of discovery

    Science.gov (United States)

    2017-12-01

    What started 50 years ago as a `smudge' on paper has flourished into a fundamental field of astrophysics replete with unexpected applications and exciting discoveries. To celebrate the discovery of pulsars, we look at the past, present and future of pulsar astrophysics.

  15. SkyDiscovery: Humans and Machines Working Together

    Science.gov (United States)

    Donalek, Ciro; Fang, K.; Drake, A. J.; Djorgovski, S. G.; Graham, M. J.; Mahabal, A.; Williams, R.

    2011-01-01

    Synoptic sky surveys are now discovering tens to hundreds of transient events every clear night, and that data rate is expected to increase dramatically as we move towards the LSST. A key problem is classification of transients, which determines their scientific interest and possible follow-up. Some of the relevant information is contextual, and easily recognizable by humans looking at images, but it is very hard to encode in the data pipelines. Crowdsourcing (aka Citizen Science) provides one possible way to gather such information. SkyDiscovery.org is a website that allows experts and citizen science enthusiasts to work together and share information in a collaborative scientific discovery environment. Currently there are two projects running on the website. In the Event Classification project users help finding candidate transients through a series of questions related to the images shown. Event classification depends very much form the contextual information and humans are remarkably effective at recognizing noise in incomplete heterogeneous data and figuring out which contextual information is important. In the SNHunt project users are requested to look for new objects appearing on images of galaxies taken by the Catalina Real-time Transient Survey, in order to find all the supernovae occurring in nearby bright galaxies. Images are served alongside with other tools that can help the discovery. A multi level approach allows the complexity of the interface to be tailored to the expertise level of the user. An entry level user can just review images and validate events as being real, while a more advanced user would be able to interact with the data associated to an event. The data gathered will not be only analyzed and used directly for some specific science project, but also to train well-defined algorithms to be used in automating such data analysis in the future.

  16. Análisis de la casuística de 5 años en la Unidad de Quemados del Hospital Luis Vernaza, Guayaquil, Ecuador

    OpenAIRE

    R. Guerrero-Torbay; J. Palacios-Martínez; P. Salamea-Molina; M. Gilbert-Orús; MT. Chiquito-Freile

    2014-01-01

    En el periodo comprendido entre 2006 y 2010 registramos 646 ingresos a la Unidad de Quemados del Hospital Luis Vernaza, en Guayaquil, Ecuador. El género masculino fue más afectado que el femenino (70,7% frente a 29,3%). El domicilio fue el lugar donde más ocurrieron los accidentes. La llama fué la etiología más común (n=233). El 85% de los pacientes ingresados requirió algún tipo de tratamiento quirúrgico. La estancia media hospitalaria no tuvo diferencias al comparar género o edad, pero fue ...

  17. Discovery radiomics via evolutionary deep radiomic sequencer discovery for pathologically proven lung cancer detection.

    Science.gov (United States)

    Shafiee, Mohammad Javad; Chung, Audrey G; Khalvati, Farzad; Haider, Masoom A; Wong, Alexander

    2017-10-01

    While lung cancer is the second most diagnosed form of cancer in men and women, a sufficiently early diagnosis can be pivotal in patient survival rates. Imaging-based, or radiomics-driven, detection methods have been developed to aid diagnosticians, but largely rely on hand-crafted features that may not fully encapsulate the differences between cancerous and healthy tissue. Recently, the concept of discovery radiomics was introduced, where custom abstract features are discovered from readily available imaging data. We propose an evolutionary deep radiomic sequencer discovery approach based on evolutionary deep intelligence. Motivated by patient privacy concerns and the idea of operational artificial intelligence, the evolutionary deep radiomic sequencer discovery approach organically evolves increasingly more efficient deep radiomic sequencers that produce significantly more compact yet similarly descriptive radiomic sequences over multiple generations. As a result, this framework improves operational efficiency and enables diagnosis to be run locally at the radiologist's computer while maintaining detection accuracy. We evaluated the evolved deep radiomic sequencer (EDRS) discovered via the proposed evolutionary deep radiomic sequencer discovery framework against state-of-the-art radiomics-driven and discovery radiomics methods using clinical lung CT data with pathologically proven diagnostic data from the LIDC-IDRI dataset. The EDRS shows improved sensitivity (93.42%), specificity (82.39%), and diagnostic accuracy (88.78%) relative to previous radiomics approaches.

  18. Un empresario agrícola porfirista en Morelos. El caso de Luis García Pimentel

    Directory of Open Access Journals (Sweden)

    María Carolina Moguel Pasquel

    2017-01-01

    Full Text Available El objetivo del artículo es presentar la vida y trayectoria del empresario agrícola Luis García Pimentel, reconocido representante de la elite regional porfiriana de Morelos, propietario de dos haciendas azucareras ubicadas al oriente de la entidad, la de Santa Ana Tenango y la de Santa Clara Montefalco. El personaje se estudió desde el ámbito de la historia económica, mediante una escrupulosa investigación en siete archivos, y en bibliografía concerniente y actualizada del tema. Cabe destacar que no existen estudios similares de empresarios porfiristas de Morelos y la importancia de documentos encontrados en el Archivo de Notarias de la Ciudad de México que aportan información relevante y desconocida en fuentes secundarias. La monografía muestra cómo antes de la revolución, García Pimentel se desempeñaba exitosamente en los negocios, conocía su entorno y lo aprovechaba para aumentar sus ganancias. Tras la lucha armada, sin embargo, no pudo recuperar el auge económico anterior.

  19. Sustainability Metrics: The San Luis Basin Project

    Science.gov (United States)

    Sustainability is about promoting humanly desirable dynamic regimes of the environment. Metrics: ecological footprint, net regional product, exergy, emergy, and Fisher Information. Adaptive management: (1) metrics assess problem, (2) specific problem identified, and (3) managemen...

  20. Integration and analysis of neighbor discovery and link quality estimation in wireless sensor networks.

    Science.gov (United States)

    Radi, Marjan; Dezfouli, Behnam; Abu Bakar, Kamalrulnizam; Abd Razak, Shukor

    2014-01-01

    Network connectivity and link quality information are the fundamental requirements of wireless sensor network protocols to perform their desired functionality. Most of the existing discovery protocols have only focused on the neighbor discovery problem, while a few number of them provide an integrated neighbor search and link estimation. As these protocols require a careful parameter adjustment before network deployment, they cannot provide scalable and accurate network initialization in large-scale dense wireless sensor networks with random topology. Furthermore, performance of these protocols has not entirely been evaluated yet. In this paper, we perform a comprehensive simulation study on the efficiency of employing adaptive protocols compared to the existing nonadaptive protocols for initializing sensor networks with random topology. In this regard, we propose adaptive network initialization protocols which integrate the initial neighbor discovery with link quality estimation process to initialize large-scale dense wireless sensor networks without requiring any parameter adjustment before network deployment. To the best of our knowledge, this work is the first attempt to provide a detailed simulation study on the performance of integrated neighbor discovery and link quality estimation protocols for initializing sensor networks. This study can help system designers to determine the most appropriate approach for different applications.