WorldWideScience

Sample records for digital assistant pda

  1. A Personal Digital Assistant (PDA) system for data acquisition during shoreline assessment field surveys

    International Nuclear Information System (INIS)

    Lamarche, A.; Owens, E.H.; Laflamme, A.; Laforest, S.; Clement, S.

    2004-01-01

    The Shoreline Cleanup Assessment Technique (SCAT) is a recognized method in North America to collect shoreline information and report observations on an oil spill. The long processing time required to analyze SCAT observations sometimes causes delays in oil spill response. Computerized systems have been developed to address this problem, but data entry of SCAT within such system involves much effort and is subject to potential errors. This paper described the development of a tool dedicated to the field capture of SCAT data on a Windows CE based Personal Digital Assistant (PDA). The system is compatible with both the SCAT methodology and Global Positioning System technology. A prototype of the system was tested during oil spills in Ontario and Nova Scotia. This paper described how the field data collection system was designed, developed and tested. Details of some user interfaces were provided to demonstrate how the large paper Shoreline Oiling Summary forms were made to fit on the small display screen of pocket-size devices. 8 refs., 1 tab., 12 figs

  2. Rapid access to information resources in clinical biochemistry: medical applications of Personal Digital Assistants (PDA).

    Science.gov (United States)

    Serdar, Muhittin A; Turan, Mustafa; Cihan, Murat

    2008-06-01

    Laboratory specialists currently need to access scientific-based information at anytime and anywhere. A considerable period of time and too much effort are required to access this information through existing accumulated data. Personal digital assistants (PDA) are supposed to provide an effective solution with commercial software for this problem. In this study, 11 commercial software products (UpToDate, ePocrates, Inforetrive, Pepid, eMedicine, FIRST Consult, and 5 laboratory e-books released by Skyscape and/or Isilo) were selected and the benefits of their use were evaluated by seven laboratory specialists. The assessment of the software was performed based on the number of the tests included, the software content of detailed information for each test-like process, method, interpretation of results, reference ranges, critical values, interferences, equations, pathophysiology, supplementary technical details such as sample collection principles, and additional information such as linked references, evidence-based data, test cost, etc. In terms of technique, the following items are considered: the amount of memory required to run the software, the graphical user interface, which is a user-friendly instrument, and the frequency of new and/or up-date releases. There is still no perfect program, as we have anticipated. Interpretation of laboratory results may require software with an integrated program. However, methodological data are mostly not included in the software evaluated. It seems that these shortcomings will be fixed in the near future, and PDAs and relevant medical applications will also become indispensable for all physicians including laboratory specialists in the field of training/education and in patient care.

  3. Development of a Personal Digital Assistant (PDA) based client/server NICU patient data and charting system.

    Science.gov (United States)

    Carroll, A E; Saluja, S; Tarczy-Hornoch, P

    2001-01-01

    Personal Digital Assistants (PDAs) offer clinicians the ability to enter and manage critical information at the point of care. Although PDAs have always been designed to be intuitive and easy to use, recent advances in technology have made them even more accessible. The ability to link data on a PDA (client) to a central database (server) allows for near-unlimited potential in developing point of care applications and systems for patient data management. Although many stand-alone systems exist for PDAs, none are designed to work in an integrated client/server environment. This paper describes the design, software and hardware selection, and preliminary testing of a PDA based patient data and charting system for use in the University of Washington Neonatal Intensive Care Unit (NICU). This system will be the subject of a subsequent study to determine its impact on patient outcomes and clinician efficiency.

  4. The Effects of Visual Illustrations on Learners' Achievement and Interest in PDA- (Personal Digital Assistant) Based Learning

    Science.gov (United States)

    Park, Sanghoon; Kim, Minjeong; Lee, Youngmin; Son, Chanhee; Lee, Miyoung

    2005-01-01

    PDAs (Personal Digital Assistants) have been used widely in educational settings. In this study, the visual illustration of a scientific text (cognitive-interest illustration, emotional-interest illustration, or no illustration) was manipulated to investigate its impact on student interest in instructional materials, achievement, and time spent on…

  5. Portable digital assistants (PDAs) in dentistry: part II--pilot study of PDA use in the dental clinic.

    Science.gov (United States)

    Reynolds, P A; Harper, J; Dunne, S; Cox, M; Myint, Y K

    2007-04-28

    To describe a simple technical evaluation of the access, security issues and uses of wireless networked PDAs in a dental clinic and report a pilot study investigating students' educational use of PDAs to access a Virtual Learning Environment (VLE) in a dental clinic. To undertake a technical evaluation of wireless networking to PDAs focusing on security issues, robustness of the system and accessibility particularly to educational resources. To evaluate the impact of using a PDA on undergraduate students in the dental clinic and at home. Part II describes the technical and educational evaluation of PDAs used by one group of 12 undergraduate fourth year students in the Primary Dental Care clinic. A cross over trial of six students with PDAs and six without was carried out during one semester of 12 weeks. Technical issues such as secure internet access using wireless connectivity were addressed. An assessment of the general and educational use and the students' attitudes towards using PDAs was undertaken using online questionnaires and focus group discussions. Over 90% of participants wanted PDAs as part of their dental kit. The potential of PDA use in dental training was demonstrated by a good to excellent response by over 75% of participants to having access to online support materials, particularly videos, being able to make notes for individual study and to keep a diary of their commitments to teaching sessions. Recreational use included a 100% good to excellent response to playing games and keeping a diary. The PDA proved to be a convenient and versatile mode of access to online education. Technical solutions enabled a substantial proportion of the functionality of WebCT (Web Course Tools) to be accessed by the students in a clinical environment. Both novice and experienced users were able to appreciate the use of the PDA and the less able considered that their ICT skills had improved. However, further research is needed to determine how students use a range of

  6. Firma digital en dispositivos móviles PDA

    OpenAIRE

    Emanuel Curcio, Federico

    2007-01-01

    En los últimos tiempos, uno de los campos de mayor desarrollo en las tecnologías de la información es el de la seguridad criptográfica y, más concretamente, el de la firma digital. Al mismo tiempo, se ha hecho cada vez mas extendido el uso de los dispositivos móviles PDA. Estos dispositivos se han convertido en verdaderos ordenadores de bolsillo, con capacidades que prácticamente igualan las de sus pares de sobremesa o portátiles. Este proyecto surge de la idea de impl...

  7. Why Don’t Physicians Use Their Personal Digital Assistants?

    OpenAIRE

    Lu, Yen-Chiao; Lee, Jin (Janet) Kyung; Xiao, Yan; Sears, Andrew; Jacko, Julie A.; Charters, Kathleen

    2003-01-01

    As the Personal Digital Assistant (PDA) user population continues to expand, there is a need to design more useful devices and applications to facilitate the utilization of PDAs. We conducted a structured interview study to examine PDA usage and non-usage patterns among physicians. The purpose of this descriptive study was to identify the barriers that impede physicians in their PDA use. A data collection tool was developed to record: 1) how physicians use their PDAs, 2) functions and applica...

  8. PDA Use by Clinicians has a Positive Impact on Clinical Decision Making. A review of: Dee, Cheryl R., Marilyn Teolis, and Andrew D. Todd. “Physicians’ use of the personal digital assistant (PDA in clinical decision making.” Journal of the Medical Library Association 93.4 (October 2005: 480-6.

    Directory of Open Access Journals (Sweden)

    Suzanne P. Lewis

    2006-06-01

    Full Text Available Objective – To examine how frequently attending physicians and physicians in training (medical students, interns and residents used PDAs for patient care and to explore physicians’ perceptions of the impact of PDA use on several aspects of clinical care. Design – User study via a questionnaire. Setting – Teaching hospitals in Tennessee, Florida, Alabama, Kentucky, and Pennsylvania in the United States. Subjects – A convenience sample of fifty nine attending physicians and forty-nine physicians in training (108 total, spread unevenly across the five states. Methods – Subjects were recruited by librarians at teaching hospitals to answer a questionnaire which was distributed and collected at medical meetings, as well as by email, mail, and fax. The subjects were required to have and use a PDA, but prior training on PDA use was not a requirement, nor was it offered to the subjects before the study. Most of the questions required the respondent to choose from five Likert scale answers regarding frequency of PDA use: almost always, often, a few times, rarely, or never. In the reporting of results, the options ‘almost always’ and ‘often’ were combined and reported as ‘frequent’, and the options ‘a few times’ and ‘rarely’, were combined and reported as ‘occasional’. Subjects could also record comments for each question, but only for affirmative responses. Subjects were asked about their frequency of PDA use before, during, or after a patient encounter. They were also asked if PDA use had influenced one or more of five aspects of clinical care – decision making, diagnosis, treatment, test ordering, and in-patient hospital length of stay. Data analysis included chi square tests to assess differences between attending physicians and physicians in training regarding frequency of PDA use and the influence of PDA use on the five aspects of clinical care. The subject population was also divided into frequent and occasional

  9. Digital knowledge in the coat pocket - hand-held personal digital assistants in radiology

    International Nuclear Information System (INIS)

    Niehues, S.M.; Froehlich, M.; Felix, R.; Lemke, A.J.

    2004-01-01

    The personal digital assistant (PDA) enables the independent access to large data in a pocket-sized format. The applications for hand-held computers are growing steadily and can support almost any kind of problem. An overview of the available hardware and software is provided and evaluated. Furthermore, the use of the PDA in the clinical daily routine is described. In view of the numerous software programs available in radiology, the range of software solutions for radiologists is presented. Despite the high acquisition cost, the PDA has already become the digital assistant for the radiologist. After a short time of getting used to the PDA, nobody wants to miss it at work or at home. New technical features and available software programs will continuously increase the integration of the PDA into the medical workflow in the near future. (orig.)

  10. Infusing PDA technology into nursing education.

    Science.gov (United States)

    White, Ann; Allen, Patricia; Goodwin, Linda; Breckinridge, Daya; Dowell, Jeffery; Garvy, Ryan

    2005-01-01

    Use of the personal digital assistant (PDA) has been infused into the accelerated baccalaureate program at Duke University to help prepare nursing students for professional practice. The authors provide an overview of the use of PDAs in the classroom, laboratory, and clinical setting. Technical aspects of PDA infusion and steps to ensure regulatory compliance are explored. Benefits of PDA use by both faculty and students in the program and challenges met with the infusion of this technology are also described.

  11. Using a Personal Digital Assistant to Increase Independent Task Completion by Students with Autism Spectrum Disorder

    Science.gov (United States)

    Mechling, Linda C.; Gast, David L.; Seid, Nicole H.

    2009-01-01

    In this study, a personal digital assistant (PDA) with picture, auditory, and video prompts with voice over, was evaluated as a portable self-prompting device for students with autism spectrum disorder (ASD). Using a multiple probe design across three cooking recipes and replicated with three students with ASD, the system was tested for its…

  12. Prospective, randomized evaluation of a personal digital assistant-based research tool in the emergency department

    Directory of Open Access Journals (Sweden)

    Dinizio Anthony

    2008-01-01

    Full Text Available Abstract Background Personal digital assistants (PDA offer putative advantages over paper for collecting research data. However, there are no data prospectively comparing PDA and paper in the emergency department. The aim of this study was to prospectively compare the performance of PDA and paper enrollment instruments with respect to time required and errors generated. Methods We randomized consecutive patients enrolled in an ongoing prospective study to having their data recorded either on a PDA or a paper data collection instrument. For each method, we recorded the total time required for enrollment, and the time required for manual transcription (paper onto a computer database. We compared data error rates by examining missing data, nonsensical data, and errors made during the transcription of paper forms. Statistical comparisons were performed by Kruskal-Wallis and Poisson regression analyses for time and errors, respectively. Results We enrolled 68 patients (37 PDA, 31 paper. Two of 31 paper forms were not available for analysis. Total data gathering times, inclusive of transcription, were significantly less for PDA (6:13 min per patient compared to paper (9:12 min per patient; p Conclusion Using a PDA-based data collection instrument for clinical research reduces the time required for data gathering and significantly improves data integrity.

  13. Serial personal digital assistant data capture of health-related quality of life: A randomized controlled trial in a prostate cancer clinic

    Directory of Open Access Journals (Sweden)

    Ritvo Paul

    2007-07-01

    Full Text Available Abstract Background In clinical and research practice linked to prostate cancer treatment, frequent monitoring of patient health-related quality of life (HRQOL is essential. Practical and analytic limitations of paper questionnaire data capture may be overcome with the use of self-administered personal digital assistant (PDA data collection. The objective of this study was to assess the reliability, validity, and feasibility of using PDA in place of paper versions of the International Prostate Symptom Score (IPSS, the Patient Oriented Prostate Cancer Utility Survey (PORPUS, and the International Index of Erectile Function-5 (IIEF-5 in a prostate cancer clinic setting. Methods 152 participants were randomly assigned to one of three conditions: 1 paper followed by PDA survey; 2 PDA followed by paper survey; or 3 PDA followed by PDA survey. Evaluation included an assessment of data quality (internal consistency, test-retest reliability, response correlation, completeness of data, and feasibility (participation rates, time to completion, preference and difficultly/ease of using PDA. Results Internal consistency was similar for both PDA and paper applications. Test-retest reliability was confirmed for PDA repeated administration. Data from paper and PDA questionnaires were strongly correlated. Lower missed item rates were found in PDA administration. 82.8% of participants preferred using the PDA or had no preference. Mean difficulty/ease ratings indicated that participants found the PDA easy to use. Age did not significantly correlate with preference or difficulty. Conclusion The results confirm the adaptability of the IPSS, IIEF-5, and the PORPUS to PDA administration. Similarly, the findings of this study support the feasibility of using PDA technology for HRQOL serial data capture in the prostate cancer patient population.

  14. PDA Use by Physicians: Where Do They Fit with Emerging Technologies and Use of Electronic Health Records in Office Practices?

    Directory of Open Access Journals (Sweden)

    Kimberly A. Galt

    2012-01-01

    Full Text Available This cross-sectional study explores physicians' attitudes and beliefs about the use of personal digital assistant (PDA in the context of other health information technology (HIT use and HIT-based applications safety in ambulatory care practices. The relationship of PDA use and patient safety is also explored. Ambulatory care physicians in Nebraska and South Dakota were surveyed from July to November of 2007 using a modified Dillman technique. Respondents were in one of three groups: PDA Users (those using a PDA for patient care, Other Technology Users (those not using a PDA, but using other technologies for patient care, and Non-Users (those not using any technology for patient care. PDAs are used by 43% of responding physicians, who tend to be younger and salaried. PDA Users exposed to PDAs during training continued use in practice. PDA Users believed the device enabled them to provide more efficient and better care, reduce errors, and improve patient safety.

  15. A personal digital assistant application (MobilDent) for dental fieldwork data collection, information management and database handling.

    Science.gov (United States)

    Forsell, M; Häggström, M; Johansson, O; Sjögren, P

    2008-11-08

    To develop a personal digital assistant (PDA) application for oral health assessment fieldwork, including back-office and database systems (MobilDent). System design, construction and implementation of PDA, back-office and database systems. System requirements for MobilDent were collected, analysed and translated into system functions. User interfaces were implemented and system architecture was outlined. MobilDent was based on a platform with. NET (Microsoft) components, using an SQL Server 2005 (Microsoft) for data storage with Windows Mobile (Microsoft) operating system. The PDA devices were Dell Axim. System functions and user interfaces were specified for MobilDent. User interfaces for PDA, back-office and database systems were based on. NET programming. The PDA user interface was based on Windows suitable to a PDA display, whereas the back-office interface was designed for a normal-sized computer screen. A synchronisation module (MS Active Sync, Microsoft) was used to enable download of field data from PDA to the database. MobilDent is a feasible application for oral health assessment fieldwork, and the oral health assessment database may prove a valuable source for care planning, educational and research purposes. Further development of the MobilDent system will include wireless connectivity with download-on-demand technology.

  16. How residents and interns utilise and perceive the personal digital assistant and UpToDate

    Directory of Open Access Journals (Sweden)

    Lim Tow

    2008-07-01

    Full Text Available Abstract Background In this era of evidence-based medicine, doctors are increasingly using information technology to acquire medical knowledge. This study evaluates how residents and interns utilise and perceive the personal digital assistant (PDA and the online resource UpToDate. Methods This is a questionnaire survey of all residents and interns in a tertiary teaching hospital. Results Out of 168 doctors, 134 (79.8% responded to the questionnaire. Only 54 doctors (40.3% owned a PDA. Although these owners perceived that the PDA was most useful for providing drug information, followed by medical references, scheduling and medical calculators, the majority of them did not actually have medical software applications downloaded on their PDAs. The greatest concerns highlighted for the PDA were the fear of loss and breakage, and the preference for working with desktop computers and paper. Meanwhile, only 76 doctors (56.7% used UpToDate, even though the hospital had an institutional subscription for it. Although 93.4% of these users would recommend UpToDate to a colleague, only 57.9% stated that the use of UpToDate had led to a change in their management of patients. Conclusion Although UpToDate and various PDA software applications were deemed useful by some of the residents and interns in our study, both digital tools were under-utilised. More should be done to facilitate the use of medical software applications on PDAs, to promote awareness of tools for evidence-based medicine such as UpToDate, and to facilitate the application of evidence-based medicine in daily clinical practice.

  17. House officer procedure documentation using a personal digital assistant: a longitudinal study

    Directory of Open Access Journals (Sweden)

    Lane David R

    2006-01-01

    Full Text Available Abstract Background Personal Digital Assistants (PDAs have been integrated into daily practice for many emergency physicians and house officers. Few objective data exist that quantify the effect of PDAs on documentation. The objective of this study was to determine whether use of a PDA would improve emergency medicine house officer documentation of procedures and patient resuscitations. Methods Twelve first-year Emergency Medicine (EM residents were provided a Palm V (Palm, Inc., Santa Clara, California, USA PDA. A customizable patient procedure and encounter program was constructed and loaded into each PDA. Residents were instructed to enter information on patients who had any of 20 procedures performed, were deemed clinically unstable, or on whom follow-up was obtained. These data were downloaded to the residency coordinator's desktop computer on a weekly basis for 36 months. The mean number of procedures and encounters performed per resident over a three year period were then compared with those of 12 historical controls from a previous residency class that had recorded the same information using a handwritten card system for 36 months. Means of both groups were compared a two-tailed Student's t test with a Bonferroni correction for multiple comparisons. One hundred randomly selected entries from both the PDA and handwritten groups were reviewed for completeness. Another group of 11 residents who had used both handwritten and PDA procedure logs for one year each were asked to complete a questionnaire regarding their satisfaction with the PDA system. Results Mean documentation of three procedures significantly increased in the PDA vs handwritten groups: conscious sedation 24.0 vs 0.03 (p = 0.001; thoracentesis 3.0 vs 0.0 (p = 0.001; and ED ultrasound 24.5 vs. 0.0 (p = 0.001. In the handwritten cohort, only the number of cardioversions/defibrillations (26.5 vs 11.5 was statistically increased (p = 0.001. Of the PDA entries, 100% were entered

  18. Soldier Flexible Personal Digital Assistant Program

    National Research Council Canada - National Science Library

    Price, Mark; Woytowich, Jason; Carlson, Marc

    2008-01-01

    The main goal of the Soldier Flexible Personal Digital Assistant Program was to develop prototypes of a novel flexible display technology device for demonstration in a laboratory setting and use in Future Force Warrior (FFW) demonstrations...

  19. Ultrasound-assisted extraction of azadirachtin from dried entire fruits of Azadirachta indica A. Juss. (Meliaceae) and its determination by a validated HPLC-PDA method.

    Science.gov (United States)

    de Paula, Joelma Abadia Marciano; Brito, Lucas Ferreira; Caetano, Karen Lorena Ferreira Neves; de Morais Rodrigues, Mariana Cristina; Borges, Leonardo Luiz; da Conceição, Edemilson Cardoso

    2016-01-01

    Azadirachta indica A. Juss., also known as neem, is a Meliaceae family tree from India. It is globally known for the insecticidal properties of its limonoid tetranortriterpenoid derivatives, such as azadirachtin. This work aimed to optimize the azadirachtin ultrasound-assisted extraction (UAE) and validate the HPLC-PDA analytical method for the measurement of this marker in neem dried fruit extracts. Box-Behnken design and response surface methodology (RSM) were used to investigate the effect of process variables on the UAE. Three independent variables, including ethanol concentration (%, w/w), temperature (°C), and material-to-solvent ratio (gmL(-1)), were studied. The azadirachtin content (µgmL(-1)), i.e., dependent variable, was quantified by the HPLC-PDA analytical method. Isocratic reversed-phase chromatography was performed using acetonitrile/water (40:60), a flow of 1.0mLmin(-1), detection at 214nm, and C18 column (250×4.6mm(2), 5µm). The primary validation parameters were determined according to ICH guidelines and Brazilian legislation. The results demonstrated that the optimal UAE condition was obtained with ethanol concentration range of 75-80% (w/w), temperature of 30°C, and material-to-solvent ratio of 0.55gmL(-1). The HPLC-PDA analytical method proved to be simple, selective, linear, precise, accurate and robust. The experimental values of azadirachtin content under optimal UAE conditions were in good agreement with the RSM predicted values and were superior to the azadirachtin content of percolated extract. Such findings suggest that UAE is a more efficient extractive process in addition to being simple, fast, and inexpensive. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Integration of Personal Digital Assistant (PDA) Devices into the Military Healthcare Clinic Environment

    National Research Council Canada - National Science Library

    Keltner, Jason

    2001-01-01

    .... The family practice staff at the Naval Hospital Lemoore explored and contrasted the capabilities of commercially available PDAs, wireless interfaces, and medical software applications to ascertain...

  1. Integration of Personal Digital Assistant (PDA) Devices into the Military Healthcare Clinic Environment

    National Research Council Canada - National Science Library

    Keltner, Jason

    2001-01-01

    The business drivers within managed care are mandating that physicians have point-of-care access to medical reference data, patient specific data, formularies, treatment protocols, and billing/coding information...

  2. Infectious Disease Information Collection System at the Scene of Disaster Relief Based on a Personal Digital Assistant.

    Science.gov (United States)

    Li, Ya-Pin; Gao, Hong-Wei; Fan, Hao-Jun; Wei, Wei; Xu, Bo; Dong, Wen-Long; Li, Qing-Feng; Song, Wen-Jing; Hou, Shi-Ke

    2017-12-01

    The objective of this study was to build a database to collect infectious disease information at the scene of a disaster through the use of 128 epidemiological questionnaires and 47 types of options, with rapid acquisition of information regarding infectious disease and rapid questionnaire customization at the scene of disaster relief by use of a personal digital assistant (PDA). SQL Server 2005 (Microsoft Corp, Redmond, WA) was used to create the option database for the infectious disease investigation, to develop a client application for the PDA, and to deploy the application on the server side. The users accessed the server for data collection and questionnaire customization with the PDA. A database with a set of comprehensive options was created and an application system was developed for the Android operating system (Google Inc, Mountain View, CA). On this basis, an infectious disease information collection system was built for use at the scene of disaster relief. The creation of an infectious disease information collection system and rapid questionnaire customization through the use of a PDA was achieved. This system integrated computer technology and mobile communication technology to develop an infectious disease information collection system and to allow for rapid questionnaire customization at the scene of disaster relief. (Disaster Med Public Health Preparedness. 2017;11:668-673).

  3. Open source platform Digital Personal Assistant

    OpenAIRE

    Usachev, Denis; Khusnutdinov, Azat; Mazzara, Manuel; Khan, Adil; Panchenko, Ivan

    2018-01-01

    Nowadays Digital Personal Assistants (DPA) become more and more popular. DPAs help to increase quality of life especially for elderly or disabled people. In this paper we develop an open source DPA and smart home system as a 3-rd party extension to show the functionality of the assistant. The system is designed to use the DPA as a learning platform for engineers to provide them with the opportunity to create and test their own hypothesis. The DPA is able to recognize users' commands in natura...

  4. PDA: Pooled DNA analyzer

    Directory of Open Access Journals (Sweden)

    Lin Chin-Yu

    2006-04-01

    Full Text Available Abstract Background Association mapping using abundant single nucleotide polymorphisms is a powerful tool for identifying disease susceptibility genes for complex traits and exploring possible genetic diversity. Genotyping large numbers of SNPs individually is performed routinely but is cost prohibitive for large-scale genetic studies. DNA pooling is a reliable and cost-saving alternative genotyping method. However, no software has been developed for complete pooled-DNA analyses, including data standardization, allele frequency estimation, and single/multipoint DNA pooling association tests. This motivated the development of the software, 'PDA' (Pooled DNA Analyzer, to analyze pooled DNA data. Results We develop the software, PDA, for the analysis of pooled-DNA data. PDA is originally implemented with the MATLAB® language, but it can also be executed on a Windows system without installing the MATLAB®. PDA provides estimates of the coefficient of preferential amplification and allele frequency. PDA considers an extended single-point association test, which can compare allele frequencies between two DNA pools constructed under different experimental conditions. Moreover, PDA also provides novel chromosome-wide multipoint association tests based on p-value combinations and a sliding-window concept. This new multipoint testing procedure overcomes a computational bottleneck of conventional haplotype-oriented multipoint methods in DNA pooling analyses and can handle data sets having a large pool size and/or large numbers of polymorphic markers. All of the PDA functions are illustrated in the four bona fide examples. Conclusion PDA is simple to operate and does not require that users have a strong statistical background. The software is available at http://www.ibms.sinica.edu.tw/%7Ecsjfann/first%20flow/pda.htm.

  5. Personal digital assistants are comparable to traditional diaries for dietary self-monitoring during a weight loss program.

    Science.gov (United States)

    Yon, Bethany A; Johnson, Rachel K; Harvey-Berino, Jean; Gold, Beth Casey; Howard, Alan B

    2007-04-01

    Dietary self-monitoring is considered the core of behavioral weight control programs. As software for personal digital assistants (PDA) has become more available, this study investigated whether the use of a PDA would improve dietary self-monitoring frequency and subsequent weight loss over the use of traditional paper diaries. One-hundred-seventy-six adults (BMI 25-39.9) participated in a 6-month behavioral weight control program. Treatment subjects (n = 61) were provided with a PalmZire 21 with Calorie King's Diet Diary software installed. Their self-monitoring habits and weight loss were compared with the results from a previous program (n = 115) which followed the same protocol using paper diaries for self-monitoring. No significant differences in weight loss or dietary self-monitoring were found. More frequent self-monitoring correlated with weight loss in both groups (pself-monitoring that is fitting to their lifestyle and skills.

  6. Examining the Factors Affecting PDA Acceptance among Physicians: An Extended Technology Acceptance Model.

    Science.gov (United States)

    Basak, Ecem; Gumussoy, Cigdem Altin; Calisir, Fethi

    2015-01-01

    This study aims at identifying the factors affecting the intention to use personal digital assistant (PDA) technology among physicians in Turkey using an extended Technology Acceptance Model (TAM). A structural equation-modeling approach was used to identify the variables that significantly affect the intention to use PDA technology. The data were collected from 339 physicians in Turkey. Results indicated that 71% of the physicians' intention to use PDA technology is explained by perceived usefulness and perceived ease of use. On comparing both, the perceived ease of use has the strongest effect, whereas the effect of perceived enjoyment on behavioral intention to use is found to be insignificant. This study concludes with the recommendations for managers and possible future research.

  7. GDA (Geologic Data Assistant), an ArcPad extension for geologic mapping: code, prerequisites, and instructions

    Science.gov (United States)

    ,

    2006-01-01

    GDA (Geologic Data Assistant) is an extension to ArcPad, a mobile mapping software program by Environmental Systems Research Institute (ESRI) designed to run on personal digital assistant (PDA) computers. GDA and ArcPad allow a PDA to replace the paper notebook and field map traditionally used for geologic mapping. GDA allows easy collection of field data.

  8. Computer assisted visualization of digital mammography images

    International Nuclear Information System (INIS)

    Funke, M.; Breiter, N.; Grabbe, E.; Netsch, T.; Biehl, M.; Peitgen, H.O.

    1999-01-01

    Purpose: In a clinical study, the feasibility of using a mammography workstation for the display and interpretation of digital mammography images was evaluated and the results were compared with the corresponding laser film hard copies. Materials and Methods: Digital phosphorous plate radiographs of the entire breast were obtained in 30 patients using a direct magnification mammography system. The images were displayed for interpretation on the computer monitor of a dedicated mammography workstation and also presented as laser film hard copies on a film view box for comparison. The images were evaluted with respect to the image handling, the image quality and the visualization of relevant structures by 3 readers. Results: Handling and contrast of the monitor displayed images were found to be superior compared with the film hard copies. Image noise was found in some cases but did not compromise the interpretation of the monitor images. The visualization of relevant structures was equal with both modalities. Altogether, image interpretation with the mammography workstation was considered to be easy, quick and confident. Conclusions: Computer-assisted visualization and interpretation of digital mammography images using a dedicated workstation can be performed with sufficiently high diagnostic accuracy. (orig.) [de

  9. Development of a prototype of the tele-localisation system in radiotherapy using personal digital assistant via wireless communication.

    Science.gov (United States)

    Wu, Vincent Wing-Cheung; Tang, Fuk-hay; Cheung, Wai-kwan; Chan, Kit-chi

    2013-02-01

    In localisation of radiotherapy treatment field, the oncologist is present at the simulator to approve treatment details produced by the therapist. Problems may arise if the oncologist is not available and the patient requires urgent treatment. The development of a tele-localisation system is a potential solution, where the oncologist uses a personal digital assistant (PDA) to localise the treatment field on the image sent from the simulator through wireless communication and returns the information to the therapist after his or her approval. Our team developed the first tele-localisation prototype, which consisted of a server workstation (simulator) for the administration of digital imaging and communication in medicine localisation images including viewing and communication with the PDA via a Wi-Fi network; a PDA (oncologist's site) installed with the custom-built programme that synchronises with the server workstation and performs treatment field editing. Trial tests on accuracy and speed of the prototype system were conducted on 30 subjects with the treatment regions covering the neck, skull, chest and pelvis. The average time required in performing the localisation using the PDA was less than 1.5 min, with the blocked field longer than the open field. The transmission speed of the four treatment regions was similar. The average physical distortion of the images was within 4.4% and the accuracy of field size indication was within 5.3%. Compared with the manual method, the tele-localisation system presented with an average deviation of 5.5%. The prototype system fulfilled the planned objectives of tele-localisation procedure with reasonable speed and accuracy. © 2012 The Authors. Journal of Medical Imaging and Radiation Oncology © 2012 The Royal Australian and New Zealand College of Radiologists.

  10. Development of a personal digital assistant-based wireless application in clinical practice.

    Science.gov (United States)

    Chen, Yen-Cheng; Chiu, Hou-Chang; Tsai, Ming-Dar; Chang, Hang; Chong, Chee-Fah

    2007-02-01

    Our study aims to develop a personal digital assistant (PDA)-based wireless application in medical information processing by using Bluetooth and IEEE 802.11b wireless standards and SyncML codes. In this study, an "integrated database access module" is used to provide a unified integrated access interface while consistency of wireless data transmission is achieved by using the standardized SyncML protocol. A prototype of the system has been developed, implemented, and tested for its mobility, usability, stability, and performance with questionnaire survey. Response time for browsing/searching was usually less than 3s. The average time intervals needed for data transmissions were 68.6+/-8.5s for Bluetooth and 47.0+/-4.8s for 802.11b. The five-point Likert scale (from 1=least to 5=most) questionnaire survey of 30 medical professionals yielded a high degree of satisfaction with the system's mobility (4.18+/-0.89), usability (4.69+/-0.90), stability (3.81+/-0.94), and performance (3.97+/-0.88). The results of our study suggested that PDA applications which exploit wireless communication are convenient and feasible in clinical practice.

  11. Development and validation of simple RP-HPLC-PDA analytical protocol for zileuton assisted with Design of Experiments for robustness determination

    OpenAIRE

    Saurabh B. Ganorkar; Dinesh M. Dhumal; Atul A. Shirkhedkar

    2017-01-01

    A simple, rapid, sensitive, robust, stability-indicating RP-HPLC-PDA analytical protocol was developed and validated for the analysis of zileuton racemate in bulk and in tablet formulation. Development of method and resolution of degradation products from forced; hydrolytic (acidic, basic, neutral), oxidative, photolytic (acidic, basic, neutral, solid state) and thermal (dry heat) degradation was achieved on a LC – GC Qualisil BDS C18 column (250 mm × 4.6 mm × 5 μm) by isocratic mode at ambie...

  12. User Evaluation of a Soldier Flexible Display Personal Digital Assistant

    National Research Council Canada - National Science Library

    Sampson, James B; Boynton, Angela C; Mitchell, K. B; Magnifico, Dennis S; DuPont, Frederick J

    2008-01-01

    The U.S. Army Natick Soldier Research, Development and Engineering Center and U.S. Army Research Laboratory, Human Research and Engineering Directorate conducted an evaluation of a Soldier Flexible Display Personal Digital Assistant...

  13. Digitally assisted pipeline ADCs theory and implementation

    CERN Document Server

    Murmann, Boris

    2007-01-01

    List of Figures. List of Tables. Acknowledgements. Preface. 1: Introduction. 1. Motivation. 2. Overview. 3. Chapter Organization. 2: Performance Trends. 1. Introduction. 2. Digital Performance Trends. 3. ADC Performance Trends. 3: Scaling Analysis. 1. Introduction. 2. Basic Device Scaling from a Digital Perspective. 3. Technology Metrics for Analog Circuits. 4. Scaling Impact on Matching-Limited Circuits. 5. Scaling Impact on Noise-Limited Circuits. 4: Improving Analog Circuit Efficiency. 1. Introduction. 2. Analog Circuit Challenges. 3. The Cost of Feedback. 4. Two-Stage Feedback Amplifier vs. Open-Loop Gain Stage. 5. Discussion. 5: Open-Loop Pipelined ADCs. 1. A Brief Review of Pipelined ADCs. 2. Conventional Stage Implementation. 3. Open-Loop Pipeline Stages. 4. Alternative Transconductor Implementations. 6: Digital Nonlinearity Correction. 1. Overview. 2. Error Model and Digital Correction. 3. Alternative Error Models. 7: Statistics-Based Parameter Estimation. 1. Introduction. 2. Modulation Approach. 3. R...

  14. Development and validation of simple RP-HPLC-PDA analytical protocol for zileuton assisted with Design of Experiments for robustness determination

    Directory of Open Access Journals (Sweden)

    Saurabh B. Ganorkar

    2017-02-01

    Full Text Available A simple, rapid, sensitive, robust, stability-indicating RP-HPLC-PDA analytical protocol was developed and validated for the analysis of zileuton racemate in bulk and in tablet formulation. Development of method and resolution of degradation products from forced; hydrolytic (acidic, basic, neutral, oxidative, photolytic (acidic, basic, neutral, solid state and thermal (dry heat degradation was achieved on a LC – GC Qualisil BDS C18 column (250 mm × 4.6 mm × 5 μm by isocratic mode at ambient temperature, employing a mobile phase methanol and (0.2%, v/v orthophosphoric acid in ratio of (80:20, v/v at a flow rate of 1.0 mL min−1 and detection at 260 nm. ‘Design of Experiments’ (DOE employing ‘Central Composite Design’ (CCD and ‘Response Surface Methodology’ (RSM were applied as an advancement to traditional ‘One Variable at Time’ (OVAT approach to evaluate the effects of variations in selected factors (methanol content, flow rate, concentration of orthophosphoric acid as graphical interpretation for robustness and statistical interpretation was achieved with Multiple Linear Regression (MLR and ANOVA. The method succeeded over the validation parameters: linearity, precision, accuracy, limit of detection and limit of quantitation, and robustness. The method was applied effectively for analysis of in-house zileuton tablets.

  15. The use of a personal digital assistant for dietary self-monitoring does not improve the validity of self-reports of energy intake.

    Science.gov (United States)

    Yon, Bethany Ann; Johnson, Rachel K; Harvey-Berino, Jean; Gold, Beth Casey

    2006-08-01

    Underreporting of energy intake is a pervasive problem and resistant to improvement, especially among people with overweight and obesity. The goal of this study was to investigate whether the use of a personal digital assistant (PDA) for dietary self-monitoring would reduce underreporting prevalence and improve the validity of self-reported energy intake. Adults with overweight and obesity (n=61, 92% women, mean age 48.2 years, mean body mass index 32.3) were provided with a PalmZire 21 (Palm, Inc, Sunnyvale, CA) loaded with Calorie King's Diet Diary software (version 3.2.2, 2002, Family Health Network, Costa Mesa, CA). Subjects participated in a 24-week in-person behavioral weight control program and were asked to self-monitor their diet and exercise habits using the PDA. Basal metabolic rate and physical activity level were estimated at baseline. Energy intake from 7-day electronic food records were collected within the first month of the weight-control program. As subjects were actively losing weight, Bandini's adjustments were used to correct self-reported energy intake for weight loss. In this group, where 41% of the subjects were categorized as low-energy reporters, the use of a PDA did not improve validity of energy reporting when compared to what is reported in the literature.

  16. [Constructing 3-dimensional colorized digital dental model assisted by digital photography].

    Science.gov (United States)

    Ye, Hong-qiang; Liu, Yu-shu; Liu, Yun-song; Ning, Jing; Zhao, Yi-jiao; Zhou, Yong-sheng

    2016-02-18

    digital dental model with better color simulation can be constructed assisted by 3D dental scanning system and digital photography. In clinical practice, the communication between dentist and patients could be improved assisted by the better visual perception since the colorized 3D digital dental models with better color simulation effect.

  17. Awareness and use of digital assistants by University of Ilorin ...

    African Journals Online (AJOL)

    Awareness and use of digital assistants by University of Ilorin postgraduate students. ... agents that help people with communication, information and time management. ... the use of DAs by postgraduate students of the University of Ilorin, Nigeria. ... By Country · List All Titles · Free To Read Titles This Journal is Open Access.

  18. An electromagnetic signals monitoring and analysis wireless platform employing personal digital assistants and pattern analysis techniques

    Science.gov (United States)

    Ninos, K.; Georgiadis, P.; Cavouras, D.; Nomicos, C.

    2010-05-01

    This study presents the design and development of a mobile wireless platform to be used for monitoring and analysis of seismic events and related electromagnetic (EM) signals, employing Personal Digital Assistants (PDAs). A prototype custom-developed application was deployed on a 3G enabled PDA that could connect to the FTP server of the Institute of Geodynamics of the National Observatory of Athens and receive and display EM signals at 4 receiver frequencies (3 KHz (E-W, N-S), 10 KHz (E-W, N-S), 41 MHz and 46 MHz). Signals may originate from any one of the 16 field-stations located around the Greek territory. Employing continuous recordings of EM signals gathered from January 2003 till December 2007, a Support Vector Machines (SVM)-based classification system was designed to distinguish EM precursor signals within noisy background. EM-signals corresponding to recordings preceding major seismic events (Ms≥5R) were segmented, by an experienced scientist, and five features (mean, variance, skewness, kurtosis, and a wavelet based feature), derived from the EM-signals were calculated. These features were used to train the SVM-based classification scheme. The performance of the system was evaluated by the exhaustive search and leave-one-out methods giving 87.2% overall classification accuracy, in correctly identifying EM precursor signals within noisy background employing all calculated features. Due to the insufficient processing power of the PDAs, this task was performed on a typical desktop computer. This optimal trained context of the SVM classifier was then integrated in the PDA based application rendering the platform capable to discriminate between EM precursor signals and noise. System's efficiency was evaluated by an expert who reviewed 1/ multiple EM-signals, up to 18 days prior to corresponding past seismic events, and 2/ the possible EM-activity of a specific region employing the trained SVM classifier. Additionally, the proposed architecture can form a

  19. The development and evaluation of a PDA-based method for public health surveillance data collection in developing countries

    DEFF Research Database (Denmark)

    Yu, Ping; de Courten, Maximilian; Pan, Elaine

    2009-01-01

    EpiData and Epi Info are often used together by public health agencies around the world, particularly in developing countries, to meet their needs of low-cost public health data management; however, the current open source data management technology lacks a mobile component to meet the needs...... of mobile public health data collectors. The goal of this project is to explore the opportunity of filling this gap through developing and trial of a personal digital assistant (PDA) based data collection/entry system. It evaluated whether such a system could increase efficiency and reduce data...

  20. Air assisted dispersive liquid-liquid microextraction with solidification of the floating organic droplets (AA-DLLME-SFO) and UHPLC-PDA method: Application to antibiotics analysis in human plasma of hospital acquired pneumonia patients.

    Science.gov (United States)

    Ferrone, Vincenzo; Cotellese, Roberto; Carlucci, Maura; Di Marco, Lorenzo; Carlucci, Giuseppe

    2018-03-20

    An ultra high-performance liquid chromatographic (UHPLC) method with PDA detection was developed and validated for the simultaneous quantification of metronidazole, meropenem, ciprofloxacin, linezolid and piperacillin in human plasma and applied to patients suffering from hospital acquired pneumonia (HAP). The method uses an air assisted dispersive liquid-liquid microextraction for sample preparation. All parameters in the extraction step, including selection of extractant, amount of extractant, ionic strength, pH, and extraction cycles, were investigated and optimized. Chromatography was carried out using a Poroshell 120 SB C 18 (50 × 2.1 mm I.D. 2.6 μm particle size) column and a gradient mobile phase consisting of ammonium acetate buffer (10 mM, pH 4.0) (eluent A); and a mixture of acetonitrile-methanol in a ratio (80/20)(eluent B). Ulifloxacin was used as internal standard. The method demonstrated good linearity with correlation coefficients, r 2  > 0.9995 for the drugs, as well as high precision (RSD% ≤ 9.87%), accuracy ranged from -8.14% to +8.98. The enrichment factor (EF) obtained ranged within 87 and 121. During the validation, the concentrations of the analytes were found to be stable after 3 freeze-thaw cycles and for at least 24 h after extraction. Subsequently, this method was used to quantify the drugs in patients with HAP in order to establish if the dosage regimen given was sufficient to eradicate the infection at the target site. Copyright © 2017. Published by Elsevier B.V.

  1. Blending technology in teaching advanced health assessment in a family nurse practitioner program: using personal digital assistants in a simulation laboratory.

    Science.gov (United States)

    Elliott, Lydia; DeCristofaro, Claire; Carpenter, Alesia

    2012-09-01

    This article describes the development and implementation of integrated use of personal handheld devices (personal digital assistants, PDAs) and high-fidelity simulation in an advanced health assessment course in a graduate family nurse practitioner (NP) program. A teaching tool was developed that can be utilized as a template for clinical case scenarios blending these separate technologies. Review of the evidence-based literature, including peer-reviewed articles and reviews. Blending the technologies of high-fidelity simulation and handheld devices (PDAs) provided a positive learning experience for graduate NP students in a teaching laboratory setting. Combining both technologies in clinical case scenarios offered a more real-world learning experience, with a focus on point-of-care service and integration of interview and physical assessment skills with existing standards of care and external clinical resources. Faculty modeling and advance training with PDA technology was crucial to success. Faculty developed a general template tool and systems-based clinical scenarios integrating PDA and high-fidelity simulation. Faculty observations, the general template tool, and one scenario example are included in this article. ©2012 The Author(s) Journal compilation ©2012 American Academy of Nurse Practitioners.

  2. Personal Digital Assistant-Based Self-Work Sampling Study of Pediatric Interns Quantifies Workday and Educational Value.

    Science.gov (United States)

    Campbell, Joyce K; Ortiz, Michael V; Ottolini, Mary C; Birch, Sarah; Agrawal, Dewesh

    2017-04-01

    Optimizing clinical proficiency and education of residents has become more important with restricted residency duty hours. Our objective was to investigate how interns spend their time on inpatient rotations and the perceived educational value of workday activities. We performed a descriptive self-work sampling study using a personal digital assistant (PDA) to randomly query interns on inpatient rotations in real time regarding their activity and the perceived educational value of that activity on a 4-point Likert scale. A total of 31 interns participated on 88 workdays over a 5-month period, generating 2082 samples from which the average workday was modeled. Time spent using the electronic health record (EHR) accounted for 33% of intern time, communicating with the health care team 23%, educational activities 17%, and time with patients and families 12%. Time with patients and families was perceived to be the most educational part of clinical service. Time spent using the EHR was perceived as the least educational. Interns perceived clinical service as excellent or good 37% of the time, while planned educational activities were perceived as excellent or good 81% of the time. Interns spend the majority of their time using the EHR and communicating with the health care team. Interns perceive time spent in planned educational activities has more educational value than time spent in clinical service. The distribution of daily activities is discordant with the perceived educational value of those activities. Copyright © 2016 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  3. Evaluation of Web and PDA-based Quality Assurance on a Building Site

    DEFF Research Database (Denmark)

    Koch, Christian; Vogelius, Peter

    2006-01-01

    Quality assurance tends to dangerously balance between redundant externalized paperwork and real life problems in everyday processes of design and construction. This leads to too many failures and complaints from customers. This paper describes an evaluative study of the implementation and use...... of a new ICT system based on the use of Personalized Digital Assistants (PDA’s) on the construction site supporting in-process quality assurance. In the pilot project we followed bricklayers using the PDA’ while they where working at a line of bathrooms. The central idea of the PDA based system (developed...... by the small Danish company ETJEK) is to lift the standard quality procedures from the paper based platform to a real-time database with direct access. The evaluation shows that system in facts works, and the introduction on the workplace was smoother than could be expected. The perspective of the evaluation...

  4. An Integrated GPS/PDA/GIS Telegeoprocessing System for Traffic and Environment

    Directory of Open Access Journals (Sweden)

    Ana Luísa Ramos

    2009-12-01

    Full Text Available The development of sustainable urban transport networks is a present priority for world leaders, national governors and local authorities. The challenge is to increase mobility reducing the adverse impacts of transport. The potential of Intelligent Transportation Systems (ITS to provide solutions for the 21 st century sustainable urban transport system has already been demonstrated in several piecewise applications. An integrated framework that addresses the needs of municipal authorities, that integrates the data spread through different sources, that supports the intelligent traffic and environment operations, and that provides information to the citizens steering their involvement and commitment is of critical importance and can be the enabler towards the creation of more efficient, safety, and environmental-friendly transport networks that promote the citizens' quality of life. This work describes an integrated GPS (Global Positioning System / PDA (Personal Digital Assistant / GIS (Geographical Information System system which is part of the mentioned framework. The system includes prototypes for mobile urban traffic data acquisition, with a GPS -equipped vehicle, a PDA application and wireless communications, and for a geodatabase with a related Web application for urban traffic and environment. Their integrated operation is exemplified for a real urban transport system.

  5. The next step: intelligent digital assistance for clinical operating rooms

    Directory of Open Access Journals (Sweden)

    Miehle Juliana

    2017-08-01

    Full Text Available With the emergence of new technologies, the surgical working environment becomes increasingly complex and comprises many medical devices that have to be taken cared of. However, the goal is to reduce the workload of the surgical team to allow them to fully focus on the actual surgical procedure. Therefore, new strategies are needed to keep the working environment manageable. Existing research projects in the field of intelligent medical environments mostly concentrate on workflow modeling or single smart features rather than building up a complete intelligent environment. In this article, we present the concept of intelligent digital assistance for clinical operating rooms (IDACO, providing the surgeon assistance in many different situations before and during an ongoing procedure using natural spoken language. The speech interface enables the surgeon to concentrate on the surgery and control the technical environment at the same time, without taking care of how to interact with the system. Furthermore, the system observes the context of the surgery and controls several devices autonomously at the appropriate time during the procedure.

  6. Technology's Latest Wave: Colleges and Universities Are Increasingly Exploring the Academic Use of Digital Mobile Devices-But Lack of Money Sometimes Stands in the Way

    Science.gov (United States)

    Galuszka, Peter

    2005-01-01

    Using mobile digital devices--iPods, personal digital assistants (PDAs), Tablet PCs or advanced cell phones--is becoming a big campus trend. Their advantages include convenience and the ability to hear lectures or course-related music just about anywhere. PDA's such as Palm Pilots and BlackBerrys, iPods such as Apple's and Tablet PCs, including…

  7. Sistema de Pesquisaje Auditivo con PEAee sobre PDA

    Directory of Open Access Journals (Sweden)

    María del Carmen Hernández Cordero

    2010-09-01

    Full Text Available Normal 0 21 false false false ES-TRAD X-NONE X-NONE MicrosoftInternetExplorer4 st1:*{behavior:url(#ieooui } /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Tabla normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;} El pesquisaje auditivo de todos los recién nacidos (universal constituye  una meta en salud a nivel mundial. Aunque existen técnicas fiables y efectivas para el pesquisaje, estas tienen limitaciones y pueden perfeccionarse. En los últimos años los Potenciales Evocados Auditivos de Estado Estable a Múltiples Frecuencias (PEAee MF se han propuesto como una alternativa efectiva para la evaluación de la audición a edad temprana y como método de detección. Sin embargo los equipos de PEAee existentes no están concebidos para su uso en la maternidad, tienen una interface con el usuario relativamente compleja y requieren conocimiento experto para su empleo adecuado. Con el objetivo de facilitar el uso del PEAee MF como método de pesquisaje, se diseño un equipo automático de pesquisaje auditivo. El equipo cuenta con dos unidades: una PDA (Personal Digital Assistant que recibe de manera inalámbrica la respuesta y un equipo registrador/estimulador, incorporando una nueva forma de estimulación auditiva. El presente trabajo describe el programa de cómputo sobre PDA y el algoritmo de funcionamiento que se desarrollo para este equipo. El sistema

  8. Rhinoplasty perioperative database using a personal digital assistant.

    Science.gov (United States)

    Kotler, Howard S

    2004-01-01

    To construct a reliable, accurate, and easy-to-use handheld computer database that facilitates the point-of-care acquisition of perioperative text and image data specific to rhinoplasty. A user-modified database (Pendragon Forms [v.3.2]; Pendragon Software Corporation, Libertyville, Ill) and graphic image program (Tealpaint [v.4.87]; Tealpaint Software, San Rafael, Calif) were used to capture text and image data, respectively, on a Palm OS (v.4.11) handheld operating with 8 megabytes of memory. The handheld and desktop databases were maintained secure using PDASecure (v.2.0) and GoldSecure (v.3.0) (Trust Digital LLC, Fairfax, Va). The handheld data were then uploaded to a desktop database of either FileMaker Pro 5.0 (v.1) (FileMaker Inc, Santa Clara, Calif) or Microsoft Access 2000 (Microsoft Corp, Redmond, Wash). Patient data were collected from 15 patients undergoing rhinoplasty in a private practice outpatient ambulatory setting. Data integrity was assessed after 6 months' disk and hard drive storage. The handheld database was able to facilitate data collection and accurately record, transfer, and reliably maintain perioperative rhinoplasty data. Query capability allowed rapid search using a multitude of keyword search terms specific to the operative maneuvers performed in rhinoplasty. Handheld computer technology provides a method of reliably recording and storing perioperative rhinoplasty information. The handheld computer facilitates the reliable and accurate storage and query of perioperative data, assisting the retrospective review of one's own results and enhancement of surgical skills.

  9. Reducing the Need for Personal Supports among Workers with Autism Using an iPod Touch as an Assistive Technology: Delayed Randomized Control Trial

    Science.gov (United States)

    Gentry, Tony; Kriner, Richard; Sima, Adam; McDonough, Jennifer; Wehman, Paul

    2015-01-01

    Personal digital assistants (PDAs) are versatile task organizers that hold promise as assistive technologies for people with cognitive-behavioral challenges. This delayed randomized controlled trial compared two groups of adult workers with autism spectrum disorder (ASD) to determine whether the use of an Apple iPod Touch PDA as a vocational…

  10. [Clinical analysis of 12 cases of orthognathic surgery with digital computer-assisted technique].

    Science.gov (United States)

    Tan, Xin-ying; Hu, Min; Liu, Chang-kui; Liu, Hua-wei; Liu, San-xia; Tao, Ye

    2014-06-01

    This study was to investigate the effect of the digital computer-assisted technique in orthognathic surgery. Twelve patients from January 2008 to December 2011 with jaw malformation were treated in our department. With the help of CT and three-dimensional reconstruction technique, 12 patients underwent surgical treatment and the results were evaluated after surgery. Digital computer-assisted technique could clearly show the status of the jaw deformity and assist virtual surgery. After surgery all patients were satisfied with the results. Digital orthognathic surgery can improve the predictability of the surgical procedure, and to facilitate patients' communication, shorten operative time, and reduce patients' pain.

  11. Improving symptom communication through personal digital assistants: the CHAT (Communicating Health Assisted by Technology) project.

    Science.gov (United States)

    Post, Douglas M; Shapiro, Charles L; Cegala, Donald J; David, Prabu; Katz, Mira L; Krok, Jessica L; Phillips, Gary S; McAlearney, Ann Sheck; Lehman, Jennifer S; Hicks, William; Paskett, Electra D

    2013-12-01

    Communication problems impede effective symptom management during chemotherapy. The primary aim of this pilot randomized controlled trial was to test the effects of a personal digital assistant-delivered communication intervention on pain, depression, and fatigue symptoms among breast cancer patients undergoing chemotherapy. Secondary aims included assessment of 1) study feasibility, 2) patient and clinician responses to study participation, and 3) intervention effects on health-related quality of life (HRQoL) and communication self-efficacy. Intervention group participants (n = 27) completed symptom inventories at baseline, once per week during treatment, and at posttreatment. Depending on symptom severity, they viewed race-concordant videos on how to communicate about pain, depression and/or fatigue, using the personal digital assistant. Symptom records were tracked and shared with clinicians. Control group participants (n = 23) received usual care. Longitudinal random effects modeling assessed the changes in average symptom scores over time. Descriptive statistics assessed study feasibility and intervention effects on HRQoL and communication self-efficacy. Postintervention focus groups, interviews, and surveys assessed responses to study participation. Mean age of the participants was 51.0 years; 42 participants (84%) were white. In comparison with control, intervention group participants reported lower average pain severity over time (P = .015). Mean pain interference scores over time were marginally different between groups (P = .07); mean depression and fatigue scores over time were statistically nonsignificant. Feasibility outcomes and perspectives about study participation were positive. Mean pre-post decreases in HRQoL were generally higher among intervention group participants; pre-post changes in communication self-efficacy were equivalent. Mixed findings of the study indicate the need for future research.

  12. Value of wireless personal digital assistants for practice: perceptions of advanced practice nurses.

    Science.gov (United States)

    Garrett, Bernard; Klein, Gerri

    2008-08-01

    The aims were to explore advanced practice nurses' perceptions on wireless Personal Digital Assistant technologies, to establish the type and range of tools that would be useful to support their practice and to identify any requirements and limitations that may impact the implementation of wireless Personal Digital Assistants in practice. The wireless Personal Digital Assistant is becoming established as a hand-held computing tool for healthcare professionals. The reflections of advanced practice nurses' about the value of wireless Personal Digital Assistants and its potential to contribute to improved patient care has not been investigated. A qualitative interpretivist design was used to explore advanced practice nurses' perceptions on the value of wireless Personal Digital Assistant technologies to support their practice. The data were collected using survey questionnaires and individual and focus group interviews with nurse practitioners, clinical nurse specialists and information technology managers based in British Columbia, Canada. An open-coding content analysis was performed using qualitative data analysis software. Wireless Personal Digital Assistant's use supports the principles of pervasivity and is a technology rapidly being adopted by advanced practice nurses. Some nurses indicated a reluctance to integrate wireless Personal Digital Assistant technologies into their practices because of the cost and the short technological life cycle of these devices. Many of the barriers which precluded the use of wireless networks within facilities are being removed. Nurses demonstrated a complex understanding of wireless Personal Digital Assistant technologies and gave good rationales for its integration in their practice. Nurses identified improved client care as the major benefit of this technology in practice and the type and range of tools they identified included clinical reference tools such as drug and diagnostic/laboratory reference applications and wireless

  13. A PDA-based Network for Telemonitoring Asthma Triggering Gases in the El Paso School Districts of the US - Mexico Border Region.

    Science.gov (United States)

    Shenoy, Namdev; Nazeran, Homer

    2005-01-01

    In this paper we describe the application of a personal digital assistant (PDA) or pocket PC as an effective communication device to telemonitor levels of asthma triggering gases collected from a remote location under test to a workstation which has a personal computer (PC) running on Windows XP® as the operating system. The Bluetooth® features of the PDA are explored to transmit data collected by a Direct™ Sense Tox toxic gas monitor equipped with five toxic gas probes and one temperature sensor in real time, thereby making this telemonitoring system an innovative instrument in monitoring levels of asthma triggering gases in the El Paso-border metropolitan region, a region in which asthma is highly prevalent especially in children. At the workstation or fixed location these readings are displayed using a custom made, user friendly graphical user interface (GUI) developed using software tools like action scripting with Macromedia® Flash™. The growing advancement in technology and ever diminishing sizes of handheld devices encouraged us to opt for this configuration. Moreover, the PDA and toxic gas monitor were also chosen for their light weight, portability, flexibility, low cost and data collection and transmission capabilities.

  14. [The digital avatar, an assistant in adolescent psychiatry].

    Science.gov (United States)

    Pommereau, Xavier; Deberdt, Jean-Patrick

    2012-01-01

    The digital universe, from the internet to video games, arouses mixed feelings in parents of adolescents. However, it is possible to use the growing "digitisation" of the relationships between young people to develop care tools. Avatars or virtual characters, for example, make it possible to develop a relationship with adolescents hospitalised in child psychiatry units.

  15. Digitally assisted analog beamforming for millimeter-wave communication

    NARCIS (Netherlands)

    Kokkeler, Andre B.J.; Smit, Gerardus Johannes Maria

    2015-01-01

    The paper addresses the research question on how digital beamsteering algorithms can be combined with analog beamforming in the context of millimeter-wave communication for next generation (5G) cellular systems. Key is the use of coarse quantisation of the individual antenna signals next to the

  16. Percutaneous Transcatheter PDA Device Closure in Infancy

    International Nuclear Information System (INIS)

    Ullah, M.; Sultan, M.; Akhtar, K.; Sadiq, N.; Akbar, H.

    2014-01-01

    Objective: To evaluate the results and complications associated with transcatheter closure of patent ductus arteriosus (PDA) in infants. Study Design: Quasi-experimental study. Place and Duration of Study: Paediatric Cardiology Department of Armed Forces Institute of Cardiology / National Institute of Heart Diseases (AFIC/NIHD), Rawalpindi, from December 2010 to June 2012. Methodology: Infants undergoing transcatheter device closure of PDA were included. All patients were evaluated by experienced Paediatric Cardiologists with 2-D echocardiography and Doppler before the procedure. Success of closure and complications were recorded. Results: The age of patients varied from 05 - 12 months and 31 (56.4%) were females. Out of the 55 infants, 3 (5.4%) were not offered device closure after aortogram (two large tubular type ducts and one tiny duct, considered unsuitable for device closure); while in 50 (96.1%) patients out of remaining 52, the duct was successfully closed with transcatheter PDA device or coil. In one infant, device deployment resulted in acquired coarctation, necessitating device retrieval by Snare followed by surgical duct interruption and another patient had non-fatal cardiac arrest during device deployment leading to abandonment of procedure and subsequent successful surgical interruption. Local vascular complications occurred in 12 (21.8%) of cases and all were satisfactorily treated. Conclusion: Transcatheter device closure of PDA in infants was an effective procedure in the majority of cases; however, here were considerable number of local access site vascular complications. (author)

  17. Use of film digitizers to assist radiology image management

    Science.gov (United States)

    Honeyman-Buck, Janice C.; Frost, Meryll M.; Staab, Edward V.

    1996-05-01

    The purpose of this development effort was to evaluate the possibility of using digital technologies to solve image management problems in the Department of Radiology at the University of Florida. The three problem areas investigated were local interpretation of images produced in remote locations, distribution of images to areas outside of radiology, and film handling. In all cases the use of a laser film digitizer interfaced to an existing Picture Archiving and Communication System (PACS) was investigated as a solution to the problem. In each case the volume of studies involved were evaluated to estimate the impact of the solution on the network, archive, and workstations. Communications were stressed in the analysis of the needs for all image transmission. The operational aspects of the solution were examined to determine the needs for training, service, and maintenance. The remote sites requiring local interpretation included were a rural hospital needing coverage for after hours studies, the University of Florida student infirmary, and the emergency room. Distribution of images to the intensive care units was studied to improve image access and patient care. Handling of films originating from remote sites and those requiring urgent reporting were evaluated to improve management functions. The results of our analysis and the decisions that were made based on the analysis are described below. In the cases where systems were installed, a description of the system and its integration into the PACS system is included. For all three problem areas, although we could move images via a digitizer to the archive and a workstation, there was no way to inform the radiologist that a study needed attention. In the case of outside films, the patient did not always have a medical record number that matched one in our Radiology Information Systems (RIS). In order to incorporate all studies for a patient, we needed common locations for orders, reports, and images. RIS orders

  18. A digitally assisted, signal folding neural recording amplifier.

    Science.gov (United States)

    Chen, Yi; Basu, Arindam; Liu, Lei; Zou, Xiaodan; Rajkumar, Ramamoorthy; Dawe, Gavin Stewart; Je, Minkyu

    2014-08-01

    A novel signal folding and reconstruction scheme for neural recording applications that exploits the 1/f(n) characteristics of neural signals is described in this paper. The amplified output is 'folded' into a predefined range of voltages by using comparison and reset circuits along with the core amplifier. After this output signal is digitized and transmitted, a reconstruction algorithm can be applied in the digital domain to recover the amplified signal from the folded waveform. This scheme enables the use of an analog-to-digital convertor with less number of bits for the same effective dynamic range. It also reduces the transmission data rate of the recording chip. Both of these features allow power and area savings at the system level. Other advantages of the proposed topology are increased reliability due to the removal of pseudo-resistors, lower harmonic distortion and low-voltage operation. An analysis of the reconstruction error introduced by this scheme is presented along with a behavioral model to provide a quick estimate of the post reconstruction dynamic range. Measurement results from two different core amplifier designs in 65 nm and 180 nm CMOS processes are presented to prove the generality of the proposed scheme in the neural recording applications. Operating from a 1 V power supply, the amplifier in 180 nm CMOS has a gain of 54.2 dB, bandwidth of 5.7 kHz, input referred noise of 3.8 μVrms and power dissipation of 2.52 μW leading to a NEF of 3.1 in spike band. It exhibits a dynamic range of 66 dB and maximum SNDR of 43 dB in LFP band. It also reduces system level power (by reducing the number of bits in the ADC by 2) as well as data rate to 80% of a conventional design. In vivo measurements validate the ability of this amplifier to simultaneously record spike and LFP signals.

  19. 31. Left ventricular dysfunction after patent ductus arteriosus (PDA closure

    Directory of Open Access Journals (Sweden)

    Rihab Agouba

    2015-10-01

    Conclusions: Depressed LV-SFx may occur after PDA closure with higher incidence after catheter PDA device occlusion. All of preterm babies had surgical PDA occlusion and none of them presented with depressed LV-SFx in the post-operative follow-up. Further prospective studies are needed to investigate these observations.

  20. Informatics in Radiology (infoRAD): mobile wireless DICOM server system and PDA with high-resolution display: feasibility of group work for radiologists.

    Science.gov (United States)

    Nakata, Norio; Kandatsu, Susumu; Suzuki, Naoki; Fukuda, Kunihiko

    2005-01-01

    A novel mobile system has been developed for use by radiologists in managing Digital Imaging and Communications in Medicine (DICOM) image data. The system consists of a mobile DICOM server (MDS) and personal digital assistants (PDAs), including a Linux PDA with a video graphics array (VGA) display (307,200 pixels, 3.7 inches). The MDS weighs 410 g, has a 60-GB hard disk drive and a built-in wireless local area network (LAN) access point, and supports a DICOM server (Central Test Node). The Linux-based MDS can be accessed with personal computers (PCs) and PDAs by means of a wireless or wired LAN, and client-server communications can be established at any time. DICOM images can be displayed by using any PDA or PC by means of a Web browser. Simultaneous access to the MDS is possible for multiple authenticated users. With most PDAs, image compression is necessary for complete display of DICOM images; however, the VGA screen can display a 512 x 512-pixel DICOM image almost in its entirety. This wireless system allows efficient management of heavy loads of lossless DICOM image data and will be useful for collaborative work by radiologists in education, conferences, and research.

  1. Nurses' satisfaction with use of a personal digital assistants with a mobile nursing information system in China.

    Science.gov (United States)

    Shen, Li-Qiong; Zang, Xiao-Ying; Cong, Ji-Yan

    2018-04-01

    Personal digital assistants, technology with various functions, have been applied in international clinical practice. Great benefits in reducing medical errors and enhancing the efficiency of clinical work have been achieved, but little research has investigated nurses' satisfaction with the use of personal digital assistants. To investigate nurses' satisfaction with use of personal digital assistants, and to explore the predictors of this. This is a cross-sectional descriptive study. We conducted a cross-sectional survey targeting nurses who used personal digital assistants in a comprehensive tertiary hospital in Beijing. A total of 383 nurses were recruited in this survey in 2015. The total score of nurses' satisfaction with use of personal digital assistants was 238.91 (SD 39.25). Nurses were less satisfied with the function of documentation, compared with the function of administering medical orders. The time length of using personal digital assistants, academic degree, and different departments predicted nurses' satisfaction towards personal digital assistant use (all P < 0.05). Nurses were satisfied with the accuracy of administering medical orders and the safety of recording data. The stability of the wireless network and efficiency related to nursing work were less promising. To some extent, nurses with higher education and longer working time with personal digital assistants were more satisfied with them. © 2018 John Wiley & Sons Australia, Ltd.

  2. Learning Tools for Knowledge Nomads: Using Personal Digital Assistants (PDAs) in Web-based Learning Environments.

    Science.gov (United States)

    Loh, Christian Sebastian

    2001-01-01

    Examines how mobile computers, or personal digital assistants (PDAs), can be used in a Web-based learning environment. Topics include wireless networks on college campuses; online learning; Web-based learning technologies; synchronous and asynchronous communication via the Web; content resources; Web connections; and collaborative learning. (LRW)

  3. Wireless remote control of clinical image workflow: using a PDA for off-site distribution and disaster recovery.

    Science.gov (United States)

    Documet, Jorge; Liu, Brent J; Documet, Luis; Huang, H K

    2006-07-01

    This paper describes a picture archiving and communication system (PACS) tool based on Web technology that remotely manages medical images between a PACS archive and remote destinations. Successfully implemented in a clinical environment and also demonstrated for the past 3 years at the conferences of various organizations, including the Radiological Society of North America, this tool provides a very practical and simple way to manage a PACS, including off-site image distribution and disaster recovery. The application is robust and flexible and can be used on a standard PC workstation or a Tablet PC, but more important, it can be used with a personal digital assistant (PDA). With a PDA, the Web application becomes a powerful wireless and mobile image management tool. The application's quick and easy-to-use features allow users to perform Digital Imaging and Communications in Medicine (DICOM) queries and retrievals with a single interface, without having to worry about the underlying configuration of DICOM nodes. In addition, this frees up dedicated PACS workstations to perform their specialized roles within the PACS workflow. This tool has been used at Saint John's Health Center in Santa Monica, California, for 2 years. The average number of queries per month is 2,021, with 816 C-MOVE retrieve requests. Clinical staff members can use PDAs to manage image workflow and PACS examination distribution conveniently for off-site consultations by referring physicians and radiologists and for disaster recovery. This solution also improves radiologists' effectiveness and efficiency in health care delivery both within radiology departments and for off-site clinical coverage.

  4. REVERSE PDA – LESS COMMON TYPE OF PATENT DUCTUS ARTERIOSUS -CASE REPORT

    Directory of Open Access Journals (Sweden)

    Iuliu Scurtu

    2016-11-01

    Full Text Available Introduction: PDA represents one of the most frequently diagnosed type of congenital heart disease. Ductus arteriosus is a normal structure in foetal life, which permits shunting of oxygenated blood from the pulmonary artery into the aorta. Failure of sealing after birth is an abnormal condition and is called patent ductus arteriosus. In normal PDA, due to fact that systemic pressure is fivefold higher than pulmonary circulation, blood is shunted from the aorta into the pulmonary artery. In reverse PDA, pulmonary artery pressure does not drop after birth, and blood will be shunted form right to left. Aims: We want to evaluate clinical, haematological, ECG and echocardiographic changes in case of reverse PDA. Materials and Methods: Two-year old female Bichon Frise was referred to our clinic with signs of effort intolerance and dyspnoea for more than a year. ECG was performed in the right lateral recumbency using a digital device and echocardiography was done with Esaote MyLab40 Vet with a phased array transducer matched with the size of the dog (7.5 MHz. Results: We identified a dog with a good body score, quite alert and without any sign of illness. Haematological investigation underlined polycythaemia and very high PCV. The ECG revealed a normal sinus rhythm with a deep S wave, changes consistent with right ventricle enlargement.  Right atrial dilation and right ventricle hypertrophy were found on cardiac ultrasonography. The right ventricle free wall was hypertrophied and interventricular septum was flattened, changes consistent with increased pressure on the right side of the heart. The left heart was small. Positive diagnosis was done, performing “bubble study” and identification of contrast bubble within the abdominal aorta.   Conclusion: Reverse PDA is a rarely diagnosed congenital heart disease. Polycythaemia in young dogs could raise the suspicion of reverse PDA.  For positive diagnosis, echocardiography and bubble study are

  5. Effect of digital template in the assistant of a giant condylar osteochondroma resection.

    Science.gov (United States)

    Bai, Guo; He, Dongmei; Yang, Chi; Lu, Chuan; Huang, Dong; Chen, Minjie; Yuan, Jianbing

    2014-05-01

    Exostosis osteochondroma is usually resected with the whole condyle even part of it is not involved. This study was to report the effect of using digital template in the assistant of resection while protecting the uninvolved condyle. We used computer-aided design technique in the assistant of making preoperative plan of a patient with giant condylar osteochondroma of exogenous type, including determining the boundary between the tumor and the articular surface of condyle, and designing the virtual tumor resection plane, surgical approach, and remove-out path of the tumor. The digital osteotomy template was made by rapid prototyping technique based on the preoperative plan. Postoperative CT scan was performed and merged with the preoperative CT by the Proplan 1.3 system to evaluate the accuracy of surgical resection with the guide of digital template. The osteotomy template was attached to the lateral surface of condyle accurately, and the tumor was removed totally by the guide of the template without injuries to adjacent nerves and vessels. Postoperative CT showed that the osteochondroma was removed completely and the unaffected articular surface of condyle was preserved well. The merging of postoperative and preoperative CT by Proplan 1.3 system showed the outcome of the operation matched with the preoperative planning quite well with an error of 0.92 mm. There was no sign of recurrence after 6 months of follow-up. The application of digital template could improve the accuracy of the giant condylar tumor resection and help to preserve the uninvolved condyle. The use of digital template could reduce injuries to the nerves and vessels as well as save time for the operation.

  6. [Guided and computer-assisted implant surgery and prosthetic: The continuous digital workflow].

    Science.gov (United States)

    Pascual, D; Vaysse, J

    2016-02-01

    New continuous digital workflow protocols of guided and computer-assisted implant surgery improve accuracy of implant positioning. The design of the future prosthesis is based on the available prosthetic space, gingival height and occlusal relationship with the opposing and adjacent teeth. The implant position and length depend on volume, density and bone quality, gingival height, tooth-implant and implant-implant distances, implant parallelism, axis and type of the future prosthesis. The crown modeled on the software will therefore serve as a guide to the future implant axis and not the reverse. The guide is made by 3D printing. The software determines surgical protocol with the drilling sequences. The unitary or plural prosthesis, modeled on the software and built before surgery, is loaded directly after implant placing, if needed. These protocols allow for a full continuity of the digital workflow. The software provides the surgeon and the dental technician a total freedom for the prosthetic-surgery guide design and the position of the implants. The prosthetic project, occlusal and aesthetic, taking the bony and surgical constraints into account, is optimized. The implant surgery is simplified and becomes less "stressful" for the patient and the surgeon. Guided and computer-assisted surgery with continuous digital workflow is becoming the technique of choice to improve the accuracy and quality of implant rehabilitation. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  7. Surgical Experience with Closure of an Isolated PDA at Muhimbili ...

    African Journals Online (AJOL)

    Results: A total of 52 patients with clinical diagnosis of PDA, 26 patients in each treatment group of either standard closure or new closure technique. ... string on the ampulla of the PDA followed by a silk ligature has proved to be efficient and reliable technique that leaves no residual lesion with no long term complications.

  8. [Research on UPLC-PDA fingerprint of andrographis paniculata and quantitative determination of 4 major constituents].

    Science.gov (United States)

    Huang, Jing-Yi; Liu, Xiao-Lin; Zhou, Shui-Ping; Tong, Ling; Ding, Li

    2014-11-01

    Andrographis paniculata from different parts and origins were analyzed by UPLC-PDA fingerprint to provide refererice for related preparation technology. Using the peak of andrographolide as reference, 27 common peaks were identified, and digitized UPLC-PDA fingerprints for 23 batches of andrographis paniculata were established in this research. Principal component analysis (PCA) was carried out after feature extraction. The contents of andrographolide, neoandrographolide, deoxyandrographolide, dehydroandrographolide were determined by external standard method. The Plackett-Burman design combined with pareto chart was used to analyze the factors influencing the robustness of the method. It was found that the medicinal part has a more remarkable influence on the quality of andrographis paniculata than the origin. The contents of the 4 lactones the differ greatly in the different parts of andrographis paniculata, and the pH of the mobile phase is an important factor that influenced the robustness of the method.

  9. From Paper to PDA: Design and Evaluation of a Clinical Ward Instruction on a Mobile Device

    Science.gov (United States)

    Kanstrup, Anne Marie; Stage, Jan

    Mobile devices with small screens and minimal facilities for interaction are increasingly being used in complex human activities for accessing and processing information, while the user is moving. This paper presents a case study of the design and evaluation of a mobile system, which involved transformation of complex text and tables to digital format on a PDA. The application domain was an emergency medical ward, and the user group was junior registrars. We designed a PDA-based system for accessing information, focusing on the ward instruction, implemented a prototype and evaluated it for usability and utility. The evaluation results indicate significant problems in the interaction with the system as well as the extent to which the system is useful for junior registrars in their daily work.

  10. Digitally-Assisted Stone Carving of a Relief Sculpture for the Parliament Buildings National Historic Site of Canada

    Science.gov (United States)

    Hayes, J.; Fai, S.; Kretz, S.; Ouimet, C.; White, P.

    2015-08-01

    The emerging field of digital fabrication is a process where three-dimensional datasets can be directly transferred to fabrication equipment to create models or even 1:1 building elements. In this paper, we will discuss the results of a collaboration between the Carleton Immersive Media Studio (CIMS), the Dominion Sculptor of Canada, and the Heritage Conservation Directorate (HCD) of Public Works and Government Services Canada (PWGSC), that utilizes digital fabrication technologies in the development of a digitally-assisted stone carving process. The collaboration couples the distinguished skill of the Dominion Sculptor with the latest digital acquisition and digital fabrication technologies for the reconstruction of a deteriorated stone bas-relief on the façade of the East Block building of the Parliament Buildings National Historic Site of Canada. The intention of the research is to establish a workflow of hybrid digital/analogue methodologies from acquisition through rehabilitation and ultimately to the fabrication of stone elements.

  11. Steering the conversation: A linguistic exploration of natural language interactions with a digital assistant during simulated driving.

    Science.gov (United States)

    Large, David R; Clark, Leigh; Quandt, Annie; Burnett, Gary; Skrypchuk, Lee

    2017-09-01

    Given the proliferation of 'intelligent' and 'socially-aware' digital assistants embodying everyday mobile technology - and the undeniable logic that utilising voice-activated controls and interfaces in cars reduces the visual and manual distraction of interacting with in-vehicle devices - it appears inevitable that next generation vehicles will be embodied by digital assistants and utilise spoken language as a method of interaction. From a design perspective, defining the language and interaction style that a digital driving assistant should adopt is contingent on the role that they play within the social fabric and context in which they are situated. We therefore conducted a qualitative, Wizard-of-Oz study to explore how drivers might interact linguistically with a natural language digital driving assistant. Twenty-five participants drove for 10 min in a medium-fidelity driving simulator while interacting with a state-of-the-art, high-functioning, conversational digital driving assistant. All exchanges were transcribed and analysed using recognised linguistic techniques, such as discourse and conversation analysis, normally reserved for interpersonal investigation. Language usage patterns demonstrate that interactions with the digital assistant were fundamentally social in nature, with participants affording the assistant equal social status and high-level cognitive processing capability. For example, participants were polite, actively controlled turn-taking during the conversation, and used back-channelling, fillers and hesitation, as they might in human communication. Furthermore, participants expected the digital assistant to understand and process complex requests mitigated with hedging words and expressions, and peppered with vague language and deictic references requiring shared contextual information and mutual understanding. Findings are presented in six themes which emerged during the analysis - formulating responses; turn-taking; back

  12. PDA Ligation in Adults – A 2-years Experience in Tikur Anbassa ...

    African Journals Online (AJOL)

    Fifty four percent of pts had PDA size 5-8mm.One patient died during reoperation . Conclusion: In developed countries , PDA is exclusively managed at infancy but in developing countries like ours, PDA may present in adults with symptoms and if there is no evidence of significant pulmonary hypertension ,PDA ligation is ...

  13. Field evaluation of personal digital assistant enabled by global positioning system : impact on quality of activity and diary data

    NARCIS (Netherlands)

    Bellemans, T.; Kochan, B.; Janssens, D.; Wets, G.; Timmermans, H.J.P.; Stopher, P.

    2016-01-01

    Tom Bellemans, Bruno Kochan, Davy Janssens, Geert Wets and Harry Timmermans (2008), ‘Field Evaluation of Personal Digital Assistant Enabled by Global Positioning System: Impact on Quality of Activity and Diary Data’, Transportation Research Record: Journal of the Transportation Research Board, No.

  14. Monitor de eventos electrocardiacos implementado en plataforma PDA Monitor of cardiac events implemented in PDA platform

    Directory of Open Access Journals (Sweden)

    John Bustamante

    .; unfortunately, its extensive use is not possible yet, due to the high costs that imply the acquisition of these equipments. For this purpose, through the utilization of personal digital assistants, a monitor of cardiac events with pre and post-symptomatic recording capacity, electrocardiographic signal visualization in real time, automatic recording of bradycardias and tachycardias and the possibility of annotation of symptoms by the patient, is designed and developed. It consists of a hardware component for the acquisition and treatment of the signals, a software for the monitoring in Palm OSÒ platform and an appliance for the discharge and analysis of the stored data. Prototype validations were realized through an electrocardiographic simulator, an arrhythmia simulator based on arrhythmia data base registers of the Massachusetts Institute of Technology and Beth Israel Hospital and on pilot tests of healthy people and of patients with arrhythmias. In this preliminary report, we show the way in which the developed prototype constitutes a viable alternative for ambulatory monitoring of arrhythmia, taking advantages of the storage capacity, processing and visualization that have the actual digital assistances with the additional advantages that its use is not restricted to only one utility and its economic accessibility is facilitated due to its wide commercial availability.

  15. Digitization

    DEFF Research Database (Denmark)

    Finnemann, Niels Ole

    2014-01-01

    what a concept of digital media might add to the understanding of processes of mediatization and what the concept of mediatization might add to the understanding of digital media. It is argued that digital media open an array of new trajectories in human communication, trajectories which were...

  16. Ad Hoc on-Demand Distance Vector (AODV Routing Protocol Performance Evaluation on Hybrid Ad Hoc Network: Comparison of Result of Ns-2 Simulation and Implementation on Testbed using PDA

    Directory of Open Access Journals (Sweden)

    Riri Sari

    2010-10-01

    Full Text Available In Mobile Ad hoc NETwork (MANET, node supplemented with wireless equipment has the capacity to manage and organise autonomously, without the presence of network infrastructures. Hybrid ad hoc network, enable several nodes to move freely (mobile to create instant communication. Independent from infrastructure. They could access the Local Area Network (LAN or the Internet. Functionalities of ad hoc network very much dependent on the routing protocol that determines the routing around node. Ad hoc On-demand Distance Vector (AODV is one of routing protocols in ad hoc network which has a reactive characteristic. This protocol is the most common protocol being researched and used. In this Research, AODV protocol investigation was conducted by developing a testbed using Personal Computer, several Laptops (the Linux Red Hat operation system 9.0 and Fedora Core 2, and Personal Digital Assistant (PDA. This research also made a complete package by mean of cross compilation for PDA iPAQ. In general, results obtained from the simulation of AODV protocol using Network Simulator NS-2 are packet delivery ratio 99.89%, end-to-end delay of 0.14 seconds and routing overhead of 1,756.61 byte per second. Afterwards results from simulation were compared to results from testbed. Results obtained from testbed are as follows: the packet delivery ratio is 99.57%, the end-to-end delay is 1.004 seconds and the routing overhead is 1,360.36 byte per second.

  17. MSuPDA: A Memory Efficient Algorithm for Sequence Alignment.

    Science.gov (United States)

    Khan, Mohammad Ibrahim; Kamal, Md Sarwar; Chowdhury, Linkon

    2016-03-01

    Space complexity is a million dollar question in DNA sequence alignments. In this regard, memory saving under pushdown automata can help to reduce the occupied spaces in computer memory. Our proposed process is that anchor seed (AS) will be selected from given data set of nucleotide base pairs for local sequence alignment. Quick splitting techniques will separate the AS from all the DNA genome segments. Selected AS will be placed to pushdown automata's (PDA) input unit. Whole DNA genome segments will be placed into PDA's stack. AS from input unit will be matched with the DNA genome segments from stack of PDA. Match, mismatch and indel of nucleotides will be popped from the stack under the control unit of pushdown automata. During the POP operation on stack, it will free the memory cell occupied by the nucleotide base pair.

  18. Scout-view assisted interior digital tomosynthesis (iDTS) based on compressed-sensing theory

    Science.gov (United States)

    Park, S. Y.; Kim, G. A.; Cho, H. S.; Seo, C. W.; Je, U. K.; Park, C. K.; Lim, H. W.; Kim, K. S.; Lee, D. Y.; Lee, H. W.; Kang, S. Y.; Park, J. E.; Woo, T. H.; Lee, M. S.

    2017-12-01

    Conventional digital tomosynthesis (DTS) based on the filtered-backprojection (FBP) reconstruction requires full field-of-view scan and also relatively dense projections, which results in still high dose for medical imaging purposes. In this work, to overcome these difficulties, we propose a new type of DTS examinations, the so-called scout-view assisted interior DTS (iDTS), in which the x-ray beam span covers only a small region-of-interest (ROI) containing target diagnosis with the help of some scout views and they are used in the reconstruction to add additional information to interior ROI otherwise absent with conventional iDTS reconstruction methods. We considered an effective iterative algorithm based on compressed-sensing theory, rather than the FBP-based algorithm, for more accurate iDTS reconstruction. We implemented the proposed algorithm, performed a systematic simulation and experiment, and investigated the image characteristics. We successfully reconstructed iDTS images of substantially high accuracy and no truncation artifacts by using the proposed method, preserving superior image homogeneity, edge sharpening, and in-plane spatial resolution.

  19. Computer-Assisted Digital Image Analysis of Plus Disease in Retinopathy of Prematurity.

    Science.gov (United States)

    Kemp, Pavlina S; VanderVeen, Deborah K

    2016-01-01

    The objective of this study is to review the current state and role of computer-assisted analysis in diagnosis of plus disease in retinopathy of prematurity. Diagnosis and documentation of retinopathy of prematurity are increasingly being supplemented by digital imaging. The incorporation of computer-aided techniques has the potential to add valuable information and standardization regarding the presence of plus disease, an important criterion in deciding the necessity of treatment of vision-threatening retinopathy of prematurity. A review of literature found that several techniques have been published examining the process and role of computer aided analysis of plus disease in retinopathy of prematurity. These techniques use semiautomated image analysis techniques to evaluate retinal vascular dilation and tortuosity, using calculated parameters to evaluate presence or absence of plus disease. These values are then compared with expert consensus. The study concludes that computer-aided image analysis has the potential to use quantitative and objective criteria to act as a supplemental tool in evaluating for plus disease in the setting of retinopathy of prematurity.

  20. Audience Response Made Easy: Using Personal Digital Assistants as a Classroom Polling Tool

    Science.gov (United States)

    Menon, Anil S.; Moffett, Shannon; Enriquez, Melissa; Martinez, Miriam M.; Dev, Parvati; Grappone, Todd

    2004-01-01

    Both teachers and students benefit from an interactive classroom. The teacher receives valuable input about effectiveness, student interest, and comprehension, whereas student participation, active learning, and enjoyment of the class are enhanced. Cost and deployment have limited the use of existing audience response systems, allowing anonymous linking of teachers and students in the classroom. These limitations can be circumvented, however, by use of personal digital assistants (PDAs), which are cheaper and widely used by students. In this study, the authors equipped a summer histology class of 12 students with PDAs and wireless Bluetooth cards to allow access to a central server. Teachers displayed questions in multiple-choice format as a Web page on the server and students responded with their PDAs, a process referred to as polling. Responses were immediately compiled, analyzed, and displayed. End-of-class survey results indicated that students were enthusiastic about the polling tool. The surveys also provided technical feedback that will be valuable in streamlining future trials. PMID:14764615

  1. Just ask Siri? A pilot study comparing smartphone digital assistants and laptop Google searches for smoking cessation advice.

    Science.gov (United States)

    Boyd, Matt; Wilson, Nick

    2018-01-01

    To compare voice-activated internet searches by smartphone (two digital assistants) with laptop ones for information and advice related to smoking cessation. Responses to 80 questions on a range of topics related to smoking cessation (including the FAQ from a NHS website), compared for quality. Smartphone and internet searches as performed in New Zealand. Ranked responses to the questions. Google laptop internet searches came first (or first equal) for best quality smoking cessation advice for 83% (66/80) of the responses. Voiced questions to Google Assistant ("OK Google") came first/first equal 76% of the time vs Siri (Apple) at 28%. Google and Google Assistant were statistically significantly better than Siri searches (odds ratio 12.4 and 8.5 respectively, pGoogle internet searches and Google Assistant were found to be significantly superior to the Siri digital assistant for smoking cessation information. While expert content was returned over half the time, there is still substantial room for improvement in how these software systems deliver smoking cessation advice.

  2. Chinese Nurses' Acceptance of PDA: A Cross-Sectional Survey Using a Technology Acceptance Model.

    Science.gov (United States)

    Wang, Yanling; Xiao, Qian; Sun, Liu; Wu, Ying

    2016-01-01

    This study explores Chinese nurses' acceptance of PDA, using a questionnaire based on the framework of Technology Acceptance Model (TAM). 357 nurses were involved in the study. The results reveal the scores of the nurses' acceptance of PDA were means 3.18~3.36 in four dimensions. The younger of nurses, the higher nurses' title, the longer previous usage time, the more experienced using PDA, and the more acceptance of PDA. Therefore, the hospital administrators may change strategies to enhance nurses' acceptance of PDA, and promote the wide application of PDA.

  3. Monitor of cardiac events implemented in PDA platform

    International Nuclear Information System (INIS)

    Bustamante, John; Saenz, Jose F; Amaya, Adrian

    2007-01-01

    Ambulatory monitoring of electrocardiac events constitutes a valuable tool in the diagnosis of cardiac arrhythmias involved in pathologic processes such as myocardiopathies, post-infarction stages, autonomous cardiac system injuries, etc.; unfortunately, its extensive use is not possible yet, due to the high costs that imply the acquisition of these equipment. For this purpose, through the utilization of personal digital assistants, a monitor of cardiac events with pre and post-symptomatic recording capacity, electrocardiographic signal visualization in real time, automatic recording of bradycardias and tachycardias and the possibility of annotation of symptoms by the patient, is designed and developed. It consists of a hardware component for the acquisition and treatment of the signals, software for the monitoring in Palm OSO platform and an appliance for the discharge and analysis of the stored data. Prototype validations were realized through an electrocardiographic simulator, an arrhythmia simulator Based on arrhythmia data base registers of the Massachusetts Institute of Technology and 8eth Israel Hospital and on pilot tests of healthy people and of patients with arrhythmias. In this preliminary report, we show the way in which the developed prototype constitutes a viable alternative for ambulatory monitoring of arrhythmia, taking advantages of the storage capacity, processing and visualization that have the actual digital assistances with the additional advantages that its use is not restricted to only one utility and its economic accessibility is facilitated due to its wide commercial availability

  4. DIGITAL

    Data.gov (United States)

    Federal Emergency Management Agency, Department of Homeland Security — The Digital Flood Insurance Rate Map (DFIRM) Database depicts flood risk information and supporting data used to develop the risk data. The primary risk...

  5. Digital assist: A comparison of two note-taking methods (traditional vs. digital pen) for students with emotional behavioral disorders

    Science.gov (United States)

    Rody, Carlotta A.

    High school biology classes traditionally follow a lecture format to disseminate content and new terminology. With the inclusive practices of No Child Left Behind, the Common Core State Standards, and end-of-course exam requirement for high school diplomas, classes include a large range of achievement levels and abilities. Teachers assume, often incorrectly, that students come to class prepared to listen and take notes. In a standard diploma, high school biology class in a separate school for students with emotional and behavioral disorders, five students participated in a single-subject, alternating treatment design study that compared the use of regular pens and digital pens to take notes during 21 lecture sessions. Behavior measures were threefold between the two interventions: (a) quantity of notes taken per minute during lectures, (b) quantity of notes or notations taken during review pauses, and (c) percent of correct responses on the daily comprehension quizzes. The study's data indicated that two students were inclined to take more lecture notes when using the digital pen. Two students took more notes with the regular pen. One student demonstrated no difference in her performance with either pen type. Both female students took more notes per minute, on average, than the three males regardless of pen type. During the review pause, three of the five students only added notes or notations to their notes when using the regular pen. The remaining two students did not add to their notes. Quiz scores differed in favor of the regular pen. All five participants earned higher scores on quizzes given during regular pen sessions. However, the differences were minor, and recommendations are made for specific training in note-taking, the pause strategy, and digital pen fluency which may produce different results for both note-taking and quiz scores.

  6. Assessment of the influence factors on nasal spray droplet velocity using phase-Doppler anemometry (PDA).

    Science.gov (United States)

    Liu, Xiaofei; Doub, William H; Guo, Changning

    2011-03-01

    Droplet velocity is an important parameter that can be used to characterize nasal spray products. In this study, a phase-Doppler anemometry (PDA) system was used to measure the droplet velocities of nasal sprays. A survey of seven commercial nasal spray products showed a range of droplet velocities from 6.7 to 19.2 m/s, all significantly different from each other. A three-level, four-factor Box-Behnken design of experiments (DOE) methodology were applied to investigate the influences of actuation parameters and formulation properties on nasal spray droplet velocity using a set of placebo formulations. The DOE study shows that all four input factors (stroke length, actuation velocity, concentration of the gelling agent, and concentration of the surfactant) have significant influence on droplet velocity. An optimized quadratic model generated from the DOE results describes the inherent relationships between the input factors and droplet velocity thus providing a better understanding of the input factor influences. Overall, PDA provides a new in vitro characterization method for the evaluation of inhalation drugs through assessment of spray velocity and may assist in product development to meet drug delivery equivalency requirements. © 2011 American Association of Pharmaceutical Scientists

  7. A Computer-Assisted Learning Model Based on the Digital Game Exponential Reward System

    Science.gov (United States)

    Moon, Man-Ki; Jahng, Surng-Gahb; Kim, Tae-Yong

    2011-01-01

    The aim of this research was to construct a motivational model which would stimulate voluntary and proactive learning using digital game methods offering players more freedom and control. The theoretical framework of this research lays the foundation for a pedagogical learning model based on digital games. We analyzed the game reward system, which…

  8. Personal digital assistant-based, internet-enabled remote communication system for a wearable pneumatic biventricular assist device.

    Science.gov (United States)

    Nam, Kyoung Won; Lee, Jung Joo; Hwang, Chang Mo; Choi, Seong Wook; Son, Ho Sung; Sun, Kyung

    2007-11-01

    Currently, personal mobile communication devices have become quite common, and the applications of such devices have expanded quickly. Remote communication systems might be employed for the telemonitoring of patients or the operating status of their medical devices. In this article, we describe the development of a mobile-based artificial heart telemanagement system for use in a wearable extracorporeal pneumatic biventricular assist device, which is capable of telemonitoring and telecontrolling the operating status of the ventricular assist device from any site. The system developed herein utilized small mobile phones for the client device and adopted a standard transmission control protocol/Internet protocol communication protocol for the purposes of telecommunication. The results of in vitro and animal experiments showed that the telemanagement system developed herein operated in accordance with the desired parameters.

  9. A novel surface plasmon resonance biosensor based on the PDA-AgNPs-PDA-Au film sensing platform for horse IgG detection

    Science.gov (United States)

    Wang, Ning; Zhang, Di; Deng, Xinyu; Sun, Ying; Wang, Xinghua; Ma, Pinyi; Song, Daqian

    2018-02-01

    Herein we report a novel polydopamine-silver nanoparticle-polydopamine-gold (PDA-AgNPs-PDA-Au) film based surface plasmon resonance (SPR) biosensor for horse IgG detection. The PDA-AgNPs-PDA-Au film sensing platform was built on Au-film via layer-by-layer self-assembly. Ag ion was reduced in situ to AgNPs in presence of PDA. The top PDA layer can prevent AgNPs from being oxidized and connect with antibody via Schiff alkali reaction directly. The morphology and thickness of the modified gold film were characterized using scanning electron microscope and Talystep. Experimental results show that the PDA-AgNPs-PDA-Au film sensing platform is stable, regenerative and sensitive for horse IgG detection. The detection limit of horse IgG obtained with the present biosensor is 0.625 μg mL- 1, which is 2-fold and 4-fold lower than that obtained with biosensor based on PDA modified Au film and conventional biosensor based on MPA, respectively. Furthermore, when challenged to real serum samples, our sensor exhibited excellent specificity to horse IgG, suggesting its potential for industrial application.

  10. Mejora de la calidad y disminución de costos de censos y encuestas utilizando computadores de mano (PDA. Una aplicación en Costa Rica

    Directory of Open Access Journals (Sweden)

    Antich-Montero, Daniel

    2007-07-01

    Full Text Available Los datos sobre la población en países en desarrollo se obtienen principalmente de las visitas a los hogares. Ejércitos de entrevistadores recolectan esos datos usando cuestionarios en papel (PAPI, paper and pencil method, pero tal información se infesta de errores no aleatorios. La reciente tecnología de las entrevistas asistidas por computadora (CAPI es un avance importante sobre PAPI en lo que respecta a reducción de errores y los tiempos de espera en la disponibilidad de los datos. Pero la tecnología CAPI ha sido de difícil implementación en los países en desarrollo debido a restricciones ergonómicas, costos y delincuencia asociada a las computadoras portátiles (laptops. Por esto, el Centro Centroamericano de Población (CCP ha desarrollado un sistema CAPI para PDA (Personal Digital Assistant o computadora de mano, que podría revolucionar la forma en que los datos son obtenidos, reduciendo el fraude, errores, tiempos y costos incluso para encuestas complejas. Este artículo reporta las lecciones aprendidas de usar este sistema en el estudio CRELES en Costa Rica.

  11. Mejora de la calidad y disminución de costos de censos y encuestas utilizando computadores de mano (PDA. Una aplicación en Costa Rica

    Directory of Open Access Journals (Sweden)

    Jeisson Hidalgo-Céspedes

    2007-01-01

    Full Text Available Los datos sobre la población en países en desarrollo se obtienen principalmente de las visitas a los hogares. Ejércitos de entrevistadores recolectan esos datos usando cuestionarios en papel (PAPI, paper and pencil method, pero tal información se infesta de errores no aleatorios. La reciente tecnología de las entrevistas asistidas por computadora (CAPI es un avance importante sobre PAPI en lo que respecta a reducción de errores y los tiempos de espera en la disponibilidad de los datos. Pero la tecnología CAPI ha sido de difícil implementación en los países en desarrollo debido a restricciones ergonómicas, costos y delincuencia asociada a las computadoras portátiles (laptops. Por esto, el CCP ha desarrollado un sistema CAPI para PDA (Personal Digital Assistant o computadora de mano, que podría revolucionar la forma en que los datos son obtenidos, reduciendo el fraude, errores, tiempos y costos incluso para encuestas complejas. Este artículo reporta las lecciones aprendidas de usar este sistema en el estudio CRELES en Costa Rica.

  12. PDA-phone-based instant transmission of radiological images over a CDMA network by combining the PACS screen with a Bluetooth-interfaced local wireless link.

    Science.gov (United States)

    Kim, Dong Keun; Yoo, Sun K; Park, Jeong Jin; Kim, Sun Ho

    2007-06-01

    Remote teleconsultation by specialists is important for timely, correct, and specialized emergency surgical and medical decision making. In this paper, we designed a new personal digital assistant (PDA)-phone-based emergency teleradiology system by combining cellular communication with Bluetooth-interfaced local wireless links. The mobility and portability resulting from the use of PDAs and wireless communication can provide a more effective means of emergency teleconsultation without requiring the user to be limited to a fixed location. Moreover, it enables synchronized radiological image sharing between the attending physician in the emergency room and the remote specialist on picture archiving and communication system terminals without distorted image acquisition. To enable rapid and fine-quality radiological image transmission over a cellular network in a secure manner, progressive compression and security mechanisms have been incorporated. The proposed system is tested over a code division Multiple Access 1x-Evolution Data-Only network to evaluate the performance and to demonstrate the feasibility of this system in a real-world setting.

  13. High-speed photonically assisted analog-to-digital conversion using a continuous wave multiwavelength source and phase modulation.

    Science.gov (United States)

    Bortnik, Bartosz J; Fetterman, Harold R

    2008-10-01

    A more simple photonically assisted analog-to-digital conversion system utilizing a cw multiwavelength source and phase modulation instead of a mode-locked laser is presented. The output of the cw multiwavelength source is launched into a dispersive device (such as a single-mode fiber). This fiber creates a pulse train, where the central wavelength of each pulse corresponds to a spectral line of the optical source. The pulses can then be either dispersed again to perform discrete wavelength time stretching or demultiplexed for continuous time analog-to-digital conversion. We experimentally demonstrate the operation of both time stretched and interleaved systems at 38 GHz. The potential of integrating this type of system on a monolithic chip is discussed.

  14. Handheld computers in nursing education: PDA pilot project.

    Science.gov (United States)

    Koeniger-Donohue, Rebecca

    2008-02-01

    Interest in the use and application of handheld technology at undergraduate and graduate nursing programs across the country is growing rapidly. Personal digital assistants (PDAs) are often referred to as a "peripheral brain" because they can save time, decrease errors, and simplify information retrieval at the point of care. In addition, research results support the notion that PDAs enhance nursing clinical education and are an effective student learning resource. However, most nursing programs lack the full range of technological resources to implement and provide ongoing support for handheld technology use by faculty and students. This article describes a 9-month pilot project for the initial use of PDAs by novice faculty and students at Simmons College.

  15. Development of a PDA Based Portable Pulse Height Analyzer System

    International Nuclear Information System (INIS)

    Mankheed, Panuphong; Ngernvijit, Narippawaj; Thong-Aram, Decho

    2007-08-01

    Full text: In this research a portable pulse height analyzer system was developed by application of a Personal Digital Assistant (PDAs) palm Tungsten T model together with Single Chip SCA developed by Department of Nuclear Technology, Chulalongkorn University to be used for education and research works. Capability of the developed system could measure both the energy and the average count rate of gamma rays. The results of this research showed that the gamma energy spectrum analysis of the developed system with a 2? x 2? NaI(Tl) detector could display photo peaks of Cs-137 and Co-60 at channel 57, channel 103, and channel 117 respectively. The energy resolution was found to be 7.14% at energy 661.66 keV of Cs-137

  16. Digital immunohistochemistry wizard: image analysis-assisted stereology tool to produce reference data set for calibration and quality control.

    Science.gov (United States)

    Plancoulaine, Benoît; Laurinaviciene, Aida; Meskauskas, Raimundas; Baltrusaityte, Indra; Besusparis, Justinas; Herlin, Paulette; Laurinavicius, Arvydas

    2014-01-01

    Digital image analysis (DIA) enables better reproducibility of immunohistochemistry (IHC) studies. Nevertheless, accuracy of the DIA methods needs to be ensured, demanding production of reference data sets. We have reported on methodology to calibrate DIA for Ki67 IHC in breast cancer tissue based on reference data obtained by stereology grid count. To produce the reference data more efficiently, we propose digital IHC wizard generating initial cell marks to be verified by experts. Digital images of proliferation marker Ki67 IHC from 158 patients (one tissue microarray spot per patient) with an invasive ductal carcinoma of the breast were used. Manual data (mD) were obtained by marking Ki67-positive and negative tumour cells, using a stereological method for 2D object enumeration. DIA was used as an initial step in stereology grid count to generate the digital data (dD) marks by Aperio Genie and Nuclear algorithms. The dD were collected into XML files from the DIA markup images and overlaid on the original spots along with the stereology grid. The expert correction of the dD marks resulted in corrected data (cD). The percentages of Ki67 positive tumour cells per spot in the mD, dD, and cD sets were compared by single linear regression analysis. Efficiency of cD production was estimated based on manual editing effort. The percentage of Ki67-positive tumor cells was in very good agreement in the mD, dD, and cD sets: regression of cD from dD (R2=0.92) reflects the impact of the expert editing the dD as well as accuracy of the DIA used; regression of the cD from the mD (R2=0.94) represents the consistency of the DIA-assisted ground truth (cD) with the manual procedure. Nevertheless, the accuracy of detection of individual tumour cells was much lower: in average, 18 and 219 marks per spot were edited due to the Genie and Nuclear algorithm errors, respectively. The DIA-assisted cD production in our experiment saved approximately 2/3 of manual marking. Digital IHC wizard

  17. Meeting Report: 2013 PDA Virus & TSE Safety Forum.

    Science.gov (United States)

    Willkommen, Hannelore; Blümel, Johannes; Brorson, Kurt; Chen, Dayue; Chen, Qi; Gröner, Albrecht; Hubbard, Brian R; Kreil, Thomas R; Ruffing, Michel; Ruiz, Sol; Scott, Dorothy; Silvester, Glenda

    2014-01-01

    The report provides a summary of the presentations and discussions at the Virus & TSE Safety Forum 2013 organized by the Parenteral Drug Association (PDA) and held in Berlin, Germany, from June 4 to 6, 2013. The conference was accompanied by a workshop, "Virus Spike Preparations and Virus Removal by Filtration: New Trends and Developments". The presentations and the discussion at the workshop are summarized in a separate report that will be published in this issue of the journal as well. As with previous conferences of this series, the PDA Virus & TSE Safety Forum 2013 provided again an excellent opportunity to exchange information and opinions between the industry, research organizations, and regulatory bodies. Updates on regulatory considerations related to virus and transmissible spongiform encephalopathy (TSE) safety of biopharmaceuticals were provided by agencies of the European Union (EU), the United States (US), and Singapore. The epidemiology and detection methods of new emerging pathogens like hepatitis E virus and parvovirus (PARV 4) were exemplified, and the risk of contamination of animal-derived raw materials like trypsin was considered in particular. The benefit of using new sequence-based virus detection methods was discussed. Events of bioreactor contaminations in the past drew the attention to root cause investigations and preventive actions, which were illustrated by several examples. Virus clearance data of specific unit operations were provided; the discussion focused on the mechanism of virus clearance and on the strategic concept of viral clearance integration. As in previous years, the virus safety section was followed by a TSE section that covered recent scientific findings that may influence the risk assessment of blood and cell substrates. These included the realization that interspecies transmission of TSE by blood components in sheep is greater than predicted by assays in transgenic mice. Also, the pathogenesis and possibility of

  18. Digital Games and Assistive Technology: Improvement of Communication of Children with Cerebral Palsy

    Science.gov (United States)

    Ferreira, Maria Inês Jesus; Travassos, Xisto Lucas; Sampaio, Renelson; Pereira-Guizzo, Camila de Sousa

    2013-01-01

    This paper aims to analyze the frequency of occurrence of different forms of communication in nonspeaking children during activities with digital games. The participants in this study were three children with multiple disabilities, whose limitations were due to cerebral palsy. All the children had severe oral communication disabilities. Three…

  19. Advice : virtual sales assistant for the complete customer service process in digital markets

    OpenAIRE

    García Serrano, Ana María; Rodrigo Aguado, Luis; Hernández Diego, Josefa; Martínez Fernández, Paloma; Calle Gómez, Francisco Javier

    2002-01-01

    El trabajo presenta las principales características del proyecto ADVICE (IST 1999-11305), un proyecto de investigación cuyo principal objetivo es el desarrollo de un asistente virtual para las tiendas electrónicas que imite el comportamiento de un vendedor humano. This work present the main features of the ADVICE (IST 1999-11305) project, a research project whose main aim is to develop a virtual assistant for e-shops that imitates the behaviour of a human vendor.

  20. Perceived facilitators and inhibitors for the use of personal digital assistants (PDAs) by nurses: a systematic review.

    Science.gov (United States)

    Moloney, Clint; Becarria, Lisa

    It is clear from the literature that more investigation into the infusion of this technology within nursing is required with a particular emphasis on the advantages of documenting best practices in nursing education. Current literature highlights the importance of incorporating wireless devices in nursing organisations without discussing how effectively nurses can collect data. Good information is found on the factors of adoption and barriers associated with such devices in nursing however the evidence supplied in such findings is yet to be well substantiated. Therefore, this study conducted an investigation into the factors of adoption of wireless applications for data collection. By doing so, this review has attempted to fill-in the gap in the literature and provides insights into those factors that need to be given priority when implementing handheld technologies in nursing. The overarching aim of this systematic review was therefore to explore and confirm the facilitators and inhibitors to the adoption of handheld technology in nursing. The objective of this review was to summarise the available evidence on the facilitators and inhibitors of adopting and utilising handheld wireless technology into the nursing profession. In particular this review set out to understand the supportive interventions that assist nurses to adjust to the use of such technology. Types of participants - This review was only interested in the nursing profession and was not limited to any one culture or setting. Therefore the review included nurses both Australian and overseas who were working in acute settings, community settings, and student nurses still in an academic setting.Types of intervention(s)/phenomena of interest - The review only considered studies that were endeavouring to understand the behavioural intention and user acceptance of handheld wireless technology (PDA's) in a nursing setting.Types of studies - This review considered studies that focus on qualitative data

  1. A study of low-cost, robust assistive listening system (ALS) based on digital wireless technology.

    Science.gov (United States)

    Israsena, P; Dubsok, P; Pan-Ngum, S

    2008-11-01

    We have developed a simple, low-cost digital wireless broadcasting system prototype, intended for a classroom of hearing impaired students. The system is designed to be a low-cost alternative to an existing FM system. The system implemented is for short-range communication, with a one-transmitter, multiple-receiver configuration, which is typical for these classrooms. The data is source-coded for voice-band quality, FSK modulated, and broadcasted via a 915 MHz radio frequency. A DES encryption can optionally be added for better information security. Test results show that the system operating range is approximately ten metres, and the sound quality is close to telephone quality as intended. We also discuss performance issues such as sound, power and size, as well as transmission protocols. The test results are the proof of concept that the prototype is a viable alternative to an existing FM system. Improvements can be made to the system's sound quality via techniques such as channel coding, which is also discussed.

  2. Operación de un PLC Mediante un PDA Vía ZIGBEE

    Directory of Open Access Journals (Sweden)

    Juan Zuluaga-Botero

    2015-07-01

    Full Text Available En este artículo se muestra la parte preliminar de interconexión de un módulo ZigBee con un Asistente Digital Personal (PDA a través de la red del Sistema de telefonía Móvil Global (GSM, para aplicación futura de comunicación con un Controlador Lógico Programable (PLC. Esta aplicación permite realizar monitoreo y control del sistema, de manera remota y con dispositivos móviles siendo el alcance del proyecto de investigación. Para este proyecto inicialmente se realizan comunicaciones que permiten empalmar las tecnologías de las redes de telefonía móvil celular con la red ZigBee, haciendo una interfaz transparente para el usuario, presentando dichos resultados en este artículo. Para esto se trabaja con tramas de datos básicas a través de la red de telefonía móvil celular, mediante mensajería corta recibida por el puerto serial del Zigbee remoto, utilizando microcontroladores para el control de los módulos que conforman esta parte del sistema de comunicación, estableciendo la interfaz con el dispositivo móvil o Smartphone vía Zigbee.

  3. Using Network Oriented Research Assistant (NORA) Technology to Compare Digital Photographic With In-Person Assessment of Acne Vulgaris.

    Science.gov (United States)

    Singer, Hannah M; Almazan, Timothy; Craft, Noah; David, Consuelo V; Eells, Samantha; Erfe, Crisel; Lazzaro, Cynthia; Nguyen, Kathy; Preciado, Katy; Tan, Belinda; Patel, Vishal A

    2018-02-01

    Teledermatology has undergone exponential growth in the past 2 decades. Many technological innovations are becoming available without necessarily undergoing validation studies for specific dermatologic applications. To determine whether patient-taken photographs of acne using Network Oriented Research Assistant (NORA) result in similar lesion counts and Investigator's Global Assessment (IGA) findings compared with in-person examination findings. This pilot reliability study enrolled consecutive patients with acne vulgaris from a single general dermatology practice in Los Angeles, California, who were able to use NORA on an iPhone 6 to take self-photographs. Patients were enrolled from January 1 through March 31, 2016. Each individual underwent in-person and digital evaluation of his or her acne by the same dermatologist. A period of at least 1 week separated the in-person and digital assessments of acne. All participants were trained on how to use NORA on the iPhone 6 and take photographs of their face with the rear-facing camera. Reliability of patient-taken photographs with NORA for acne evaluation compared with in-person examination findings. Acne assessment measures included lesion count (total, inflammatory, noninflammatory, and cystic) and IGA for acne severity. A total of 69 patients (37 male [54%] and 32 female [46%]; mean [SD] age, 22.7 [7.7] years) enrolled in the study. The intraclass correlation coefficients of in-person and photograph-based acne evaluations indicated strong agreement. The intraclass correlation coefficient for total lesion count was 0.81; for the IGA, 0.75. Inflammatory lesion count, noninflammatory lesion count, and cyst count had intraclass correlation coefficients of 0.72, 0.72, and 0.82, respectively. This study found agreement between acne evaluations performed in person and from self-photographs with NORA. As a reliable telehealth technology for acne, NORA can be used as a teledermatology platform for dermatology research and can

  4. Periodontal and dental effects of surgically assisted rapid maxillary expansion, assessed by using digital study models

    Science.gov (United States)

    Siqueira, Danilo Furquim; Cardoso, Mauricio de Almeida; Capelozza, Leopoldino; Goldenberg, Dov Charles; Fernandes, Mariana dos Santos

    2015-01-01

    OBJECTIVE: The present study assessed the maxillary dental arch changes produced by surgically assisted rapid maxillary expansion (SARME). METHODS: Dental casts from 18 patients (mean age of 23.3 years) were obtained at treatment onset (T1), three months after SARME (T2) and 6 months after expansion (T3). The casts were scanned in a 3D scanner (D-250, 3Shape, Copenhagen, Denmark). Maxillary dental arch width, dental crown tipping and height were measured and assessed by ANOVA and Tukey's test. RESULTS: Increased transversal widths from T1 and T2 and the maintenance of these values from T2 and T3 were observed. Buccal teeth tipping also showed statistically significant differences, with an increase in all teeth from T1 to T2 and a decrease from T2 to T3. No statistically significant difference was found for dental crown height, except for left first and second molars, although clinically irrelevant. CONCLUSION: SARME proved to be an effective and stable procedure, with minimum periodontal hazards. PMID:26154457

  5. How the ecosystem of digital assistants can ensure the security of personal data

    Directory of Open Access Journals (Sweden)

    Alexandr V. Mamaev

    2018-05-01

    Full Text Available Number of cybercrimes is constantly rising both in Europe, and around the world. The costs incurred from such malicious activities are rising correspondingly. According to the data collected by Jupiter Research these costs increased from $1.5 trillion in 2015 to $2 trillion in 2019. That is why European Union is expected to introduce major changes to the Personal Data Protection Acts which stayed mostly unchanged since the 1990s. The consequences of those changes will be felt in countries beyond the European Union. The personal data of internet users have long become a commodity on the e-commerce market. Yet the manipulations with the personal data cause concerns among both the users, who do not fully realize how and to what purposes their data are used, and governments, who try to protect the confidentiality remains by the law. Despite that the number of incidents with data leaks continues to rise exponentially. In December 2017 the lawyers from Hill Dickinson, a UK commercial law firm, filed a lawsuit against Google regarding unlawful collection of the iPhone users’ data. Another company that is about to have problems with law is Uber Technologiesm, which sent SMS messages to its clients without obtaining formal permissions for that. Finally, in March 2018 it was Facebook which had to explain the way the personal data on more than 80 million users have leaked and ended up in the hands of a third party.  The authors of this article assessed the possibilities for introducing the ecosystem of virtual assistants and blockchain technology for safe and depersonalized data processing as well as its further use. This system opens broad unexpected opportunities for the machine-to-machine-marketing.

  6. A PDA-based flexible telecommunication system for telemedicine applications.

    Science.gov (United States)

    Nazeran, Homer; Setty, Sunil; Haltiwanger, Emily; Gonzalez, Virgilio

    2004-01-01

    Technology has been used to deliver health care at a distance for many years. Telemedicine is a rapidly growing area and recently there are studies devoted to prehospital care of patients in emergency cases. In this work we have developed a compact, reliable, and low cost PDA-based telecommunication device for telemedicine applications to transmit audio, still images, and vital signs from a remote site to a fixed station such as a clinic or a hospital in real time. This was achieved based on a client-server architecture. A Pocket PC, a miniature camera, and a hands-free microphone were used at the client site and a desktop computer running the Windows XP operating system was used as a server. The server was located at a fixed station. The system was implemented on TCP/IP and HTTP protocol. Field tests have shown that the system can reliably transmit still images, audio, and sample vital signs from a simulated remote site to a fixed station either via a wired or wireless network in real time. The Pocket PC was used at the client site because of its compact size, low cost and processing capabilities.

  7. Quantifying fish swimming behavior in response to acute exposure of aqueous copper using computer assisted video and digital image analysis

    Science.gov (United States)

    Calfee, Robin D.; Puglis, Holly J.; Little, Edward E.; Brumbaugh, William G.; Mebane, Christopher A.

    2016-01-01

    Behavioral responses of aquatic organisms to environmental contaminants can be precursors of other effects such as survival, growth, or reproduction. However, these responses may be subtle, and measurement can be challenging. Using juvenile white sturgeon (Acipenser transmontanus) with copper exposures, this paper illustrates techniques used for quantifying behavioral responses using computer assisted video and digital image analysis. In previous studies severe impairments in swimming behavior were observed among early life stage white sturgeon during acute and chronic exposures to copper. Sturgeon behavior was rapidly impaired and to the extent that survival in the field would be jeopardized, as fish would be swept downstream, or readily captured by predators. The objectives of this investigation were to illustrate protocols to quantify swimming activity during a series of acute copper exposures to determine time to effect during early lifestage development, and to understand the significance of these responses relative to survival of these vulnerable early lifestage fish. With mortality being on a time continuum, determining when copper first affects swimming ability helps us to understand the implications for population level effects. The techniques used are readily adaptable to experimental designs with other organisms and stressors.

  8. A Portable Multi-Channel γ Spectrometer Based on Bluetooth and PDA

    International Nuclear Information System (INIS)

    Yu Xinhua; Lai Wanchang; Zhang Zhen; Chen Xiaoqiang; Wang Guangxi; Yang Qiang

    2009-01-01

    Introduces an embedded GPS portable multi-channel γ spectrometer based on PDA and blue-tooth. PDA use HP iPAQ rx5700, it has GPS and bluetooth, the position accuracy of GPS isn't more than 5 m and the transmission rate of bluetooth can reach 1 MB/s, its communication distance is up to 10 m. The instrument detection limits of U, Th and K are 1.0 ppm. 1.8 ppm. 0.17%, respectively. The result of experiment proves γ spectrometer based on bluetooth and PDA has low-power, strong anti-interference capability and good portable capability. (authors)

  9. Lithium inhibits tumorigenic potential of PDA cells through targeting hedgehog-GLI signaling pathway.

    Directory of Open Access Journals (Sweden)

    Zhonglu Peng

    Full Text Available Hedgehog signaling pathway plays a critical role in the initiation and development of pancreatic ductal adenocarcinoma (PDA and represents an attractive target for PDA treatment. Lithium, a clinical mood stabilizer for mental disorders, potently inhibits the activity of glycogen synthase kinase 3β (GSK3β that promotes the ubiquitin-dependent proteasome degradation of GLI1, an important downstream component of hedgehog signaling. Herein, we report that lithium inhibits cell proliferation, blocks G1/S cell-cycle progression, induces cell apoptosis and suppresses tumorigenic potential of PDA cells through down-regulation of the expression and activity of GLI1. Moreover, lithium synergistically enhances the anti-cancer effect of gemcitabine. These findings further our knowledge of mechanisms of action for lithium and provide a potentially new therapeutic strategy for PDA through targeting GLI1.

  10. Easily fabricated and lightweight PPy/PDA/AgNW composites for excellent electromagnetic interference shielding.

    Science.gov (United States)

    Wang, Yan; Gu, Fu-Qiang; Ni, Li-Juan; Liang, Kun; Marcus, Kyle; Liu, Shu-Li; Yang, Fan; Chen, Jin-Ju; Feng, Zhe-Sheng

    2017-11-30

    Conductive polymer composites (CPCs) containing nanoscale conductive fillers have been widely studied for their potential use in various applications. In this paper, polypyrrole (PPy)/polydopamine (PDA)/silver nanowire (AgNW) composites with high electromagnetic interference (EMI) shielding performance, good adhesion ability and light weight are successfully fabricated via a simple in situ polymerization method followed by a mixture process. Benefiting from the intrinsic adhesion properties of PDA, the adhesion ability and mechanical properties of the PPy/PDA/AgNW composites are significantly improved. The incorporation of AgNWs endows the functionalized PPy with tunable electrical conductivity and enhanced EMI shielding effectiveness (SE). By adjusting the AgNW loading degree in the PPy/PDA/AgNW composites from 0 to 50 wt%, the electrical conductivity of the composites greatly increases from 0.01 to 1206.72 S cm -1 , and the EMI SE of the composites changes from 6.5 to 48.4 dB accordingly (8.0-12.0 GHz, X-band). Moreover, due to the extremely low density of PPy, the PPy/PDA/AgNW (20 wt%) composites show a superior light weight of 0.28 g cm -3 . In general, it can be concluded that the PPy/PDA/AgNW composites with tunable electrical conductivity, good adhesion properties and light weight can be used as excellent EMI shielding materials.

  11. Learning PDA skills online is feasible and acceptable to clerkship students.

    Science.gov (United States)

    Strayer, Scott M; Williams, Pamela M; Stephens, Mark B; Yew, Kenneth S

    2008-01-01

    The feasibility and acceptability of teaching medical students to use PDA clinical decision support tools via a Web-based course have not been previously evaluated. A total of 119 third-year family medicine clerkship students completed a baseline survey on PDA use, attended an introductory PDA lecture, and were invited to voluntarily access a Web-based course through Blackboard. All students had been previously issued with PDAs in their second year. At baseline, 95% of students reported having removed their PDA from its box, 59% reported using it weekly, and 71% had loaded medical applications. From August 2006--March 2007, 36 students accessed the course 610 times (range 8-54). The PDA cases comprised 63% of hits, course resources 30% of hits, and course information 6% of hits. Students evaluated the course equally to other clerkship didactics. It is feasible and acceptable to students to teach PDA decision support tools in an online course. In our setting, for the minority of students who chose to learn online, the format was successful and met their needs.

  12. PDA management in VLBW infants: experience of a level III NICU

    Directory of Open Access Journals (Sweden)

    Ana Oliveira

    2016-08-01

    Full Text Available Introduction: Hemodynamically significant patent ductus arteriosus (PDA is a common condition in very low birth weight infants. Therapeutic options include medical therapy and surgical ligation. Medical treatment is based on non-selective inhibitors of cyclooxygenases 1 and 2 (indomethacin and ibuprofen. The debate on the most appropriate treatment for the closure of the PDA is far from being closed, in the light of the currently available evidence.Aim: The objective of this study was to compare efficacy and safety of indomethacin and ibuprofen.Methods: All infants < 32 weeks of gestational age or ≤ 1,500 g of birth weight born in “Centro Hospitalar São João” between January 2005 and December 2014 were included. Those with major malformations or genetic disorders, congenital TORCH infections, transferred or deceased before 72 hours of life, outborns, and those with severe pathologies at birth were excluded. The cohort of neonates treated with indomethacin from January 2005 to December 2009 was compared to those treated with ibuprofen from January 2010 to December 2014.Results: 328 newborns were included in the study: 99 (30.2% with PDA and 229 (69.8% without. The median gestational age was 30 weeks and the median birth weight was 1,231 grams. Among the 99 patients with PDA, 21 were treated with indomethacin and 41 received ibuprofen. There was no statistically significant difference in efficacy between groups. There was a higher incidence of thrombocytopenia in the indomethacin group compared to the ibuprofen group, but there was no significant difference in any other PDA-associated comorbidities between groups.Conclusion: Our study showed that indomethacin and ibuprofen have a similar effect in closing PDA in < 32 weeks preterm infants. We found no significant differences in safety, except for thrombocytopenia. Further studies are necessary to compare both efficacy and adverse events of ibuprofen and indomethacin to identify the optimal

  13. The design of portable X-ray fluorescence analyzer based on PDA

    International Nuclear Information System (INIS)

    Zhou Jianbin; Ma Yingjie; Wang Lei; Tong Yunfu

    2010-01-01

    It designs a portable x-ray fluorescence analyzer based on PDA. The high performance Single Chip Microcomputer-C8051F060 works as the core controller on the measure-control board. The communication between PDA and measure-control board is based on Bluetooth technology. Benefiting from the rich resource on the chip of C8051F060, it's very easy to design the MCA (Multi-Channel Analyzer), detection-control circuit, peak-detection circuit compactly. WinCE OS runs on the PDA, and the analysis software is designed on the Visual Studio2005 in C++. The power of the system is supplied by the lithium battery. (authors)

  14. 16. Optimal guidance of percutaneous device closure of PDA by transthoracic echocardiography

    Directory of Open Access Journals (Sweden)

    M. Alobaidan

    2016-07-01

    Full Text Available Patent ductus arteriosus (PDA is common congenital cardiac lesion and the most accepted way of management is transcatheter occlusion by device which is usually done under fluoroscopy guidance. Transoesophageal echo cardiography and transaortic imaging were used in adult to guide the procedure which is with certain applications in pediatric age group transthoracic echocardiography (TTE in pediatric population provides excellent images for PDA and may replace the use of fluoroscopy to guide PDA closure at least in special situations. To highlight the feasibility of device closure under guidance of TTE to be applied in sick patients who are not suitable for transfer to cardiac catheter laboratory or those with contraindication to contrast and or radiation application. 18 patients from July 2013 to May 2015 underwent TTE guidance device closure of PDA, 1 patient was excluded after device embolization which necessitate retrieval under fluoroscopy (fluoro.. Conscious sedation was used in 17 patients except 1 who was sick and already ventilated in ICU, there were 11 female and 7 male, antegrade approach was used in 10 patients with partial fluoro and retrograde approach in 8 patients without fluoro. Median age is 7 months, median weight is 8 kg (3.2–11 kg, 2 patients with renal impairment, 2 with Leukemia, median procedure time is 35 min, median fluoro. is 2.2 min, PDA size were small in 13 patients and moderate in 5, immediate closure is achieved in all. The devices were ADOI, ADOS, ADOII, Occlutech, and AVP2. Device embolization in 1 with successful retrieval and second device was used with complete closure percutaneous PDA closure under TTE guidance is feasible, safe and recommended in selected patients with certain situation.

  15. Patron-Driven Acquisitions (PDA) of e-books: New life for the library catalog?

    OpenAIRE

    Urbano, Cristóbal; Zhang, Yin

    2014-01-01

    This paper highlights an overview of the conceptual approach to e-resource discoverability in academic libraries with a focus on research on the assessment of library catalog performance in the Patron-Driven Acquisitions (PDA) model for e-book collection development. Although the published literature stresses the key role of the library catalog in the PDA model for e-book acquisitions, the findings in this paper show that, until now, there has been a lack of research on users’ e-resources sea...

  16. Tratamiento de información a través de PDA

    OpenAIRE

    Georgieva Caneva, María

    2010-01-01

    El objetivo del proyecto es obtener el análisis, diseño e implementación de una aplicación con la cual una empresa será capaz de conocer el flujo de trabajo realizado por sus trabajadores gracias a la información almacenada en una PDA, ya que estos dispositivos son usados para almacenar información que puede ser consultada a cualquier hora y en cualquier lugar. Para realizar la aplicación se va a simular la sincronización del dispositivo PDA, por medio de una Base de Datos impl...

  17. Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications.

    Science.gov (United States)

    Backes, Carl H; Cheatham, Sharon L; Deyo, Grace M; Leopold, Scott; Ball, Molly K; Smith, Charles V; Garg, Vidu; Holzer, Ralf J; Cheatham, John P; Berman, Darren P

    2016-02-12

    Percutaneous closure of patent ductus arteriosus (PDA) in term neonates is established, but data regarding outcomes in infants born very preterm (closure at weights closure. Twenty-five percent (13/52) of infants were closure. Compared to precatheterization trends, percutaneous PDA closure resulted in improved respiratory status, including less exposure to mechanical ventilation (mixed effects logistic model, Pclosure at weights closure versus alternative (surgical ligation) management strategies. © 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.

  18. The impact of technical conditions of X-ray imaging on reproducibility and precision of digital computer-assisted X-ray radiogrammetry (DXR)

    International Nuclear Information System (INIS)

    Malich, A.; Boettcher, J.; Pfeil, A.; Sauner, D.; Heyne, J.P.; Petrovitch, A.; Hansch, A.; Kaiser, W.A.; Linss, W.

    2004-01-01

    To evaluate the reproducibility of imaging and analysis for bone mineral density (BMD) determination using digital computer-assisted X-ray radiogrammetry (DXR; Pronosco X-posure, version V.2, Sectra Pronosco, Denmark); to verify potential factors that influence BMD extrapolation such as tube voltage, film-focus distance (FFD), film quality and brand (Kodak T-MAT-Plus, Konika SRH, Agfa Scopix), imaging technology (conventional, digital), imaging system (Kodak, Agfa) and exposure level (mAs); and to clarify whether DXR analysis based on printouts of digital images is comparable to analysis of conventional images. The hand of a cadaver was X-rayed using varied parameters: 4-8 mAs, 40-52 kV, 90-130 cm FFD. Radiographs under standardised conditions were performed 10 times using a conventional machine (Philips Super 80 CP) and the printouts of a digital system (Digital Diagnost Philips Optimus) for the analysis of reproducibility. One image was scanned and analysed 10 times additionally for imaging reproducibility. Reliability error of the system for the imaging process using conventional radiographs-rays was 0.49% (standard conditions: 6 mAs, 40 kV, 1 m FFD), using printouts of digital images was 2.89% (4 mAs, 42 kV, 1 m FFD) and regarding the analysis process was 0.22%. BMD calculation is not affected by alterations in FFD (precision error 1.21%), mAs (0.83%) or film quality/brand (0.38%), but differs significantly depending on tube voltage (2.70%). The system was not able to analyse conventional images with tube voltages of 49/52 kV. DXR technology is stable with most of the tested parameters. Normative data should exclusively be used for calculations using similar tube voltage or correction factors. All other parameters had no significant influence on the BMD calculation. Reproducibility is high. For technical reasons it is not recommended to use the printouts of digital images for BMD determination. (orig.)

  19. Report from a Multi-Institutional Randomized Clinical Trial Examining Computer-Assisted Problem-Solving Skills Training for English- and Spanish-Speaking Mothers of Children with Newly Diagnosed Cancer

    Science.gov (United States)

    Sahler, Olle Jane Z.; Sherman, Sandra A.; Fairclough, Diane L.; Butler, Robert W.; Katz, Ernest R.; Dolgin, Michael J.; Varni, James W.; Noll, Robert B.; Phipps, Sean

    2009-01-01

    Objectives To evaluate the feasibility and efficacy of a handheld personal digital assistant (PDA)-based supplement for maternal Problem-Solving Skills Training (PSST) and to explore Spanish-speaking mothers’ experiences with it. Methods Mothers (n = 197) of children with newly diagnosed cancer were randomized to traditional PSST or PSST + PDA 8-week programs. Participants completed the Social Problem-Solving Inventory-Revised, Beck Depression Inventory-II, Profile of Mood States, and Impact of Event Scale-Revised pre-, post-treatment, and 3 months after completion of the intervention. Mothers also rated optimism, logic, and confidence in the intervention and technology. Results Both groups demonstrated significant positive change over time on all psychosocial measures. No between-group differences emerged. Despite technological “glitches,” mothers expressed moderately high optimism, appreciation for logic, and confidence in both interventions and rated the PDA-based program favorably. Technology appealed to all Spanish-speaking mothers, with younger mothers showing greater proficiency. Conclusions Well-designed, supported technology holds promise for enhancing psychological interventions. PMID:19091804

  20. Combined Synchrotron X-ray Diffraction and Digital Image Correlation Technique for Measurement of Austenite Transformation with Strain in TRIP-assisted Steels

    Energy Technology Data Exchange (ETDEWEB)

    Poling, Whitney A.; Savic, Vesna; Hector, Louis G.; Sachdev, Anil K.; Hu, Xiaohua; Devaraj, Arun; Abu-Farha, Fadi

    2016-04-05

    The strain-induced, diffusionless shear transformation of retained austenite to martensite during straining of transformation induced plasticity (TRIP) assisted steels increases strain hardening and delays necking and fracture leading to exceptional ductility and strength, which are attractive for automotive applications. A novel technique that provides the retained austenite volume fraction variation with strain in TRIP-assisted steels with improved precision is presented. Digital images of the gauge section of tensile specimens were first recorded up to selected plastic strains with a stereo digital image correlation (DIC) system. The austenite volume fraction was measured by synchrotron X-ray diffraction from small squares cut from the gage section. Strain fields in the squares were then computed by localizing the strain measurement to the corresponding region of a given square during DIC post-processing of the images recorded during tensile testing. Results obtained for a QP980 steel are used to study the influence of initial volume fraction of austenite and the austenite transformation with strain on tensile mechanical behavior.

  1. Dependable Digitally-Assisted Mixed-Signal IPs Based on Integrated Self-Test & Self-Calibration

    NARCIS (Netherlands)

    Kerkhoff, Hans G.; Wan, J.

    2010-01-01

    Heterogeneous SoC devices, including sensors, analogue and mixed-signal front-end circuits and the availability of massive digital processing capability, are being increasingly used in safety-critical applications like in the automotive, medical, and the security arena. Already a significant amount

  2. Library Catalog Log Analysis in E-Book Patron-Driven Acquisitions (PDA): A Case Study

    Science.gov (United States)

    Urbano, Cristóbal; Zhang, Yin; Downey, Kay; Klingler, Thomas

    2015-01-01

    Patron-Driven Acquisitions (PDA) is a new model used for e-book acquisition by academic libraries. A key component of this model is to make records of ebooks available in a library catalog and let actual patron usage decide whether or not an item is purchased. However, there has been a lack of research examining the role of the library catalog as…

  3. ANESTHESIA MANAGEMENT OF 775 GRAMS PREMATURE PATIENT DURING PDA LIGATION-A CASE REPORT

    Directory of Open Access Journals (Sweden)

    Gulsen KESKiN

    2016-03-01

    We believe that VLBW preterm infants by having multiple system failure may have PDA ligation in operating room if there is no optimum conditions in ICU by obtaining safe transport, performing ketamine in anesthesia induction and maintenance. [J Contemp Med 2016; 6(1.000: 47-50

  4. Evaluation of metered dose inhaler spray velocities using phase Doppler anemometry (PDA).

    Science.gov (United States)

    Liu, Xiaofei; Doub, William H; Guo, Changning

    2012-02-28

    Droplet velocity is an important parameter which can significantly influence inhalation drug delivery performance. Together with the droplet size, this parameter determines the efficiency of the deposition of MDI products at different sites within the lungs. In this study, phase Doppler anemometry (PDA) was used to investigate the instantaneous droplet velocity emitted from MDIs as well as the corresponding droplet size distribution. The nine commercial MDI products surveyed showed significantly different droplet velocities, indicating that droplet velocity could be used as a discriminating parameter for in vitro testing of MDI products. The droplet velocity for all tested MDI products decreased when the testing distance was increased from 3 cm to 6 cm from the front of mouthpiece, with CFC formulations showing a larger decrease than HFA formulations. The mean droplet diameters of the nine MDIs were also significantly different from one-another. Droplet size measurements made using PDA (a number-based technique) could not be directly compared to results obtained using laser light scattering measurements (a volume-based technique). This work demonstrates that PDA can provide unique information useful for characterizing MDI aerosol plumes and evaluating MDI drug delivery efficiency. PDA could also aid the evaluation of in vitro equivalence in support of formulation or manufacturing changes and in evaluation of abbreviated new drug applications (ANDAs) for MDIs. Published by Elsevier B.V.

  5. Digital displacements

    DEFF Research Database (Denmark)

    Pors, Anja Svejgaard

    2014-01-01

    In recent years digital reforms are being introduced in the municipal landscape of Denmark. The reforms address the interaction between citizen and local authority. The aim is, that by 2015 at least 80 per cent of all correspondence between citizens and public authority will be transmitted through...... digital interface. However, the transformation of citizen services from traditional face-to-face interaction to digital self-service gives rise to new practices; some citizens need support to be able to manage self-service through digital tools. A mixture of support and teaching, named co......-service, is a new task in public administration, where street level bureaucrats assist citizens in using the new digital solutions. The paper is based on a case study conducted primarily in a citizen service centre in Copenhagen, Denmark. Based on ethnography the paper gives an empirical account of the ongoing...

  6. Non invasive Tele-assistance through Digital Television: study Television habit / Teleasistencia no invasiva mediante televisión digital: estudio de los hábitos de consumo de televisión de los mayores

    Directory of Open Access Journals (Sweden)

    Ricardo Vizcaíno- Laorga

    2009-01-01

    Full Text Available Television habits of use by elderly people are an obligated reference when designing tele-assistance tools through digital television. Our working premise needed to corroborate and update previous research data; as a consequence of our research we found that 88% of elderly people watch television every day, percentage that increases another 5% that also used “almost every day”. We must emphasize the fact that elderly women watch television slightly more than men (4.57 hours a day compared to 4.37, and the fact that the use of television increases when the elderly doesn´t live alone. The research has also revealed that the consumption of television increases gradually in relation to the number of people living with the elderly. These references, added to the tool application “the teapot” originated in Asia, has made possible the development of Calisto´s project, an application adapted to the European culture through digital television; innovation, experience and cultural differences in the interest of elderly people.Los hábitos de consumo de la televisión de las personas mayores constituyen una referencia de estudio obligada a la hora de diseñar herramientas de teleasistencia a través de la televisión digital. Nuestra premisa de trabajo necesitaba corroborar y actualizar datos de investigaciones realizas previamente; los resultados de esta actualización indican que el 88% de los mayores ven la televisión todos los días, porcentaje al que debe sumarse otro 5% que utiliza la misma “casi todos los días”. Destaca el hecho de que las mujeres mayores ven la televisión ligeramente más que los hombres (4,57 horas diarias frente a 4,37 y el hecho de que el consumo de televisión aumenta si la persona mayor vive acompañada. Se ha detectado de igual forma que el consumo de televisión se incrementa de forma gradual en función del número de personas que convivan con la persona mayor. Estas referencias, unido a la aplicaci

  7. Sonographically-guided vacuum-assisted biopsy with digital mammography-guided skin marking of suspicious breast microcalcifications: comparison of outcomes with stereotactic biopsy in Asian women.

    Science.gov (United States)

    Hahn, Soo Yeon; Shin, Jung Hee; Han, Boo-Kyung; Ko, Eun Young

    2011-02-01

    Management of suspicious microcalcifications in very thin breasts is problematic. To evaluate whether sonographically-guided vacuum-assisted biopsy (USVAB) with digital mammography-guided skin marking (DM) for the diagnosis of breast microcalcifications is comparable to stereotactic-guided vacuum-assisted biopsy (SVAB) in Asian women with thin breasts. Retrospective review was performed for 263 consecutive suspicious microcalcification lesions in 261 women who underwent USVAB with DM or SVAB using a prone table between January 2004 and December 2007. SVAB was performed for 190 lesions and USVAB for 73 lesions. Biopsy results were correlated with surgical pathology or followed up for at least 12 months. The diagnostic outcomes of SVAB and USVAB to diagnose microcalcifications were compared. Of 263 lesions, 104 (40%) underwent surgery and 159 (60%) were followed up. SVAB and USVAB groups showed similar final categories or the extent of microcalcifications. US visible lesions were 57 (78%) of 73 at USVAB and 14 (10%) of 140 at SVAB. Of 57 US visible lesions at USVAB, 29 (51%) were not found in initial US but were detectable with the help of DM. Specimen radiographs were negative in 2.1% of lesions at SVAB and in 4.1% at USVAB (p=0.4008). The under-estimation rate and false-negative rate were similar in SVAB and USVAB. US with DM facilitates US visibility of microcalcifications. USVAB with DM can produce acceptable biopsy results, as can SVAB, to diagnose breast microcalcifications in patients with thin breasts.

  8. [Computer-assisted measurement of ocular misalignment in infants and young children using the digital Purkinje reflection pattern procedure].

    Science.gov (United States)

    Barry, J C; Effert, R; Kaupp, A; Kleine, M; Reim, M

    1994-02-01

    A digital image recording and processing system is presented that allows a quick diagnosis of microstrabismus in non-cooperative children. It is thus particularly suited for screening purposes. The Purkinje Reflection Pattern Evaluation (RPE) method is used: three small flashes are used to produce the desired Purkinje images. Two horizontal rows of the three 1st Purkinje images (anterior corneal reflections) and of the three 4th Purkinje images (posterior crystalline lens reflections) stemming from the three light sources form the characteristic Purkinje image reflection pattern. Each eye's position is calculated from the shift between the upper and lower rows of reflections by means of two simple formulae. From the angles obtained in binocular fixation and monocular fixation the manifest angle of strabismus corresponding to the angle measured in the simultaneous prism-and-cover test is computed. The measurement is performed at a fixation distance of 50 cm under natural viewing conditions. To obtain a picture one only has to get the child's attention for a short moment. The primary position is triggered with the fixation light, which is operated by a switch. The digital image recording is done with a hand-held device comprising two miniaturized video cameras, three photo flashes and a fixation light that is operated manually. An IBM-compatible PC equipped with a hard disk and two frame grabbers was adapted for the storage and processing of the pictures. The pictures are evaluated interactively in a few minutes on the workstation's monitor immediately after the measurement. To this end specially designed menu-driven software was implemented. Examples of the measuring procedure and clinical results in infants with microtropic highlight the potential of the system as a screening apparatus and for the exact measurement of small and large squint angles. Usually even 1-year-old children can cooperate well enough to get good-quality pictures in binocular fixation. The new

  9. PDA survey of quality risk management practices in the pharmaceutical, devices, & biotechnology industries.

    Science.gov (United States)

    Ahmed, Ruhi; Baseman, Harold; Ferreira, Jorge; Genova, Thomas; Harclerode, William; Hartman, Jeffery; Kim, Samuel; Londeree, Nanette; Long, Michael; Miele, William; Ramjit, Timothy; Raschiatore, Marlene; Tomonto, Charles

    2008-01-01

    In July 2006 the Parenteral Drug Association's Risk Management Task Force for Aseptic Processes, conducted an electronic survey of PDA members to determine current industry practices regarding implementation of Quality Risk Management in their organizations. This electronic survey was open and publicly available via the PDA website and targeted professionals in our industry who are involved in initiating, implementing, or reviewing risk management programs or decisions in their organizations. One hundred twenty-nine members participated and their demographics are presented in the sidebar "Correspondents Profile". Among the major findings are: *The "Aseptic Processing/Filling" operation is the functional area identified as having the greatest need for risk assessment and quality risk management. *The most widely used methodology in industry to identify risk is Failure Mode and Effects Analysis (FMEA). This tool was most widely applied in assessing change control and for adverse event, complaint, or failure investigations. *Despite the fact that personnel training was identified as the strategy most used for controlling/minimizing risk, the largest contributors to sterility failure in operations are still "Personnel". *Most companies still rely on "Manufacturing Controls" to mitigate risk and deemed the utilization of Process Analytical Technology (PAT) least important in this aspect. *A majority of correspondents verified that they did not periodically assess their risk management programs. *A majority of the correspondents desired to see case studies or examples of risk analysis implementation (as applicable to aseptic processing) in future PDA technical reports on risk management.

  10. Evaluation of droplet velocity and size from nasal spray devices using phase Doppler anemometry (PDA).

    Science.gov (United States)

    Liu, Xiaofei; Doub, William H; Guo, Changning

    2010-03-30

    To determine aerosol deposition during the inhalation drug delivery, it is important to understand the combination of velocity and droplet size together. In this study, phase Doppler anemometry (PDA) was used to simultaneously characterize the aerosol velocity and droplet size distribution (DSD) of three nasal spray pumps filled with water. Thirteen sampling positions were located in the horizontal cross-sectional area of the nasal spray plumes at a distance of 3cm from the pump orifice. The results showed droplet velocities near the center of the spray plume were higher and more consistent than those near the edge. The pumps examined showed significant differences in their aerosol velocity at the center of the spray plume, which suggest that this metric might be used as a discriminating parameter for in vitro testing of nasal sprays. Droplet size measurements performed using PDA were compared with results from laser light scattering measurements. The ability of PDA to provide simultaneous measurements of aerosol velocity and size makes it a powerful tool for the detailed investigation of nasal spray plume characteristics. Published by Elsevier B.V.

  11. A Cross-Disciplinary Successful Aging Intervention and Evaluation: Comparison of Person-to-Person and Digital-Assisted Approaches

    Directory of Open Access Journals (Sweden)

    Hui-Chuan Hsu

    2018-05-01

    Full Text Available Background: Successful aging has been the paradigm of old-age life. The purpose of this study was to implement and evaluate a cross-disciplinary intervention program using two approaches for community-based older adults in Taichung, Taiwan. Methods: The content of the intervention included successful aging concepts and preparation, physical activity, chronic disease and health management, dietary and nutrition information, cognitive training, emotional awareness and coping skills, family relationship and resilience, legal concepts regarding financial protection, and Internet use. The traditional person-to-person (P2P intervention approach was implemented among participants at urban centers, and the personal-and-digital (P&D intervention approach was implemented among participants at rural centers; before the P&D group received the intervention, participants were assessed as the control group for comparison. Results: Healthy behavior and nutrition improved for the P2P group, although not significantly. Strategies for adapting to old age and reducing ineffective coping were significantly improved in the P2P group. The ability to search for health information improved in the P&D group, and knowledge of finance-related law increased in the P2P group. Conclusion: A continuous, well-designed and evidence-based intervention program is beneficial for improving the health of older adults, or at least delaying its decline.

  12. Mn2+-coordinated PDA@DOX/PLGA nanoparticles as a smart theranostic agent for synergistic chemo-photothermal tumor therapy.

    Science.gov (United States)

    Xi, Juqun; Da, Lanyue; Yang, Changshui; Chen, Rui; Gao, Lizeng; Fan, Lei; Han, Jie

    2017-01-01

    Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn 2+ -coordinated doxorubicin (DOX)-loaded poly(lactic- co -glycolic acid) (PLGA) nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA) nanoparticles were first synthesized through a double emulsion-solvent evaporation method, and then modified with polydopamine (PDA) through self-polymerization of dopamine, leading to the formation of PDA@DOX/PLGA nanoparticles. Mn 2+ ions were then coordinated on the surfaces of PDA@DOX/PLGA to obtain Mn 2+ -PDA@DOX/PLGA nanoparticles. In our system, Mn 2+ -PDA@DOX/PLGA nanoparticles could destroy tumors in a mouse model directly, by thermal energy deposition, and could also simulate the chemotherapy by thermal-responsive delivery of DOX to enhance tumor therapy. Furthermore, the coordination of Mn 2+ could afford the high magnetic resonance (MR) imaging capability with sensitivity to temperature and pH. The results demonstrated that Mn 2+ -PDA@ DOX/PLGA nanoparticles had a great potential as a smart theranostic agent due to their imaging and tumor-growth-inhibition properties.

  13. Closed-Cell Stent-Assisted Coiling of Intracranial Aneurysms: Evaluation of Changes in Vascular Geometry Using Digital Subtraction Angiography.

    Science.gov (United States)

    Beller, Ebba; Klopp, David; Göttler, Jens; Kaesmacher, Johannes; Zimmer, Claus; Kirschke, Jan S; Prothmann, Sascha

    2016-01-01

    Stent-assisted coil embolization (SACE) plays an important role in the treatment of intracranial aneurysms. The purpose of this study was to investigate geometrical changes caused by closed-cell design stents in bifurcation and sidewall aneurysms. 31 patients with 34 aneurysms underwent SACE with closed-cell design stents. Inflow angle α, determined by aneurysm neck and afferent vessel, and angle between afferent and efferent vessel close to (δ1), respectively, more remote from the aneurysm neck (δ2) were graphically determined in 2D angiography projections. Stent assisted coiling resulted in a significant increase of all three angles from a mean value (±SEM) of α = 119° (±6.5°) pretreatment to 130° (±6.6°) posttreatment (P ≤ .001), δ1 = 129° (±6.4°) to 139° (±6.1°), (P ≤ .001) and δ2 = 115° (±8.4°) to 126° (±7.5°), (P ≤ .01). Angular change of δ1 in AcomA aneurysms was significant greater compared to sidewall aneurysms (26°±4.9° versus 8°± 2.3°, P ≤ .05). The initial angle of δ1 and δ2 revealed a significantly inverse relationship to the angle increase (δ1: r = -0.41, P ≤ .05 and δ2: r = -0.47, P ≤ .01). Moreover, angle δ1 was significantly higher in unruptured compared to ruptured aneurysms (135°±7.1° versus 103°±10.8°, P ≤ .05). Stent deployment modulates the geometry of the aneurysm-vessel complex, which may lead to favorable hemodynamic changes more similar to unruptured than to ruptured aneurysms. Our findings also suggest that the more acute-angled aneurysm-vessel anatomy, the larger the angular change. Further studies are needed to investigate whether these changes improve the clinical outcome.

  14. Closed-Cell Stent-Assisted Coiling of Intracranial Aneurysms: Evaluation of Changes in Vascular Geometry Using Digital Subtraction Angiography.

    Directory of Open Access Journals (Sweden)

    Ebba Beller

    Full Text Available Stent-assisted coil embolization (SACE plays an important role in the treatment of intracranial aneurysms. The purpose of this study was to investigate geometrical changes caused by closed-cell design stents in bifurcation and sidewall aneurysms.31 patients with 34 aneurysms underwent SACE with closed-cell design stents. Inflow angle α, determined by aneurysm neck and afferent vessel, and angle between afferent and efferent vessel close to (δ1, respectively, more remote from the aneurysm neck (δ2 were graphically determined in 2D angiography projections.Stent assisted coiling resulted in a significant increase of all three angles from a mean value (±SEM of α = 119° (±6.5° pretreatment to 130° (±6.6° posttreatment (P ≤ .001, δ1 = 129° (±6.4° to 139° (±6.1°, (P ≤ .001 and δ2 = 115° (±8.4° to 126° (±7.5°, (P ≤ .01. Angular change of δ1 in AcomA aneurysms was significant greater compared to sidewall aneurysms (26°±4.9° versus 8°± 2.3°, P ≤ .05. The initial angle of δ1 and δ2 revealed a significantly inverse relationship to the angle increase (δ1: r = -0.41, P ≤ .05 and δ2: r = -0.47, P ≤ .01. Moreover, angle δ1 was significantly higher in unruptured compared to ruptured aneurysms (135°±7.1° versus 103°±10.8°, P ≤ .05.Stent deployment modulates the geometry of the aneurysm-vessel complex, which may lead to favorable hemodynamic changes more similar to unruptured than to ruptured aneurysms. Our findings also suggest that the more acute-angled aneurysm-vessel anatomy, the larger the angular change. Further studies are needed to investigate whether these changes improve the clinical outcome.

  15. SU-E-I-45: Feasibility for Using Iodine Quantification to Assist Diagnosis in Dual Energy Contrast-Enhanced Digital Mammography

    International Nuclear Information System (INIS)

    Hwang, Y; Lin, Y; Tsai, C; Cheung, Y

    2015-01-01

    Purpose: The objective of this study is to develop quantitative calibration between image quality indexes and iodine concentration with dual-energy (DE) contrast-enhanced digital mammography (CEDM) techniques and further serve as the assistance for diagnosis. Methods: Custom-made acrylic phantom with dimensions of 24×30 cm 2 simulated breast thickness from 2 to 6 cm was used in the calibration. The phantom contained matrix of four times four holes of 3 mm deep with a diameter of 15 mm for filling contrast agent with area density ranged from 0.1 to 10 mg/cm 2 . All the image acquisitions were performed on a full-field digital mammography system (Senographe Essential, GE) with dual energy acquisitions. Mean pixel value (MPV), and contrast-to-noise ratio (CNR) were used for evaluating the relationship between image quality indexes and iodine concentration. Iodine map and CNR map could further be constructed with these calibration curves applied pixel by pixel utilized MATLAB software. Minimum iodine concentration could also be calculated with the visibility threshold of CNR=5 according the Rose model. Results: When evaluating the DE subtraction images, MPV increased linearly as the iodine concentration increased with all the phantom thickness surveyed (R 2 between 0.989 and 0.992). Lesions with increased iodine uptake could thus be enhanced in the color-encoded iodine maps, and the mean iodine concentration could be obtained through the ROI measurements. As for investigating CNR performance, linear relationships were also shown between the iodine concentration and CNR (R 2 between 0.983 and 0.990). Minimum iodine area density of 1.45, 1.73, 1.80, 1.73 and 1.72 mg/cm 2 for phantom thickness of 2, 3, 4, 5, 6 cm were calculated based on Rose’s visualization criteria. Conclusion: Quantitative calibration between image quality indexes and iodine concentrations may further serving as the assistance for analyzing contrast enhancement for patient participating the dual

  16. Computer-assisted radiology

    International Nuclear Information System (INIS)

    Lemke, H.U.

    1988-01-01

    New digital imaging modalities and more sophisticated image processing systems will have a profound effect on those areas of medicine concerned with imaging. This mainly means computer-assisted radiology (CAR) and implies a transition from analog film systems to digital imaging systems, integration of digital imaging modalities through picture archiving and communication systems (PACS) and the graduated employment of image-oriented medical work stations (MWS) for computer-assisted representation, communication, diagnosis, and therapy planning. (orig.) [de

  17. From continuing education to personal digital assistants: what do physical therapists need to support evidence-based practice in stroke management?

    Science.gov (United States)

    Salbach, Nancy M; Veinot, Paula; Jaglal, Susan B; Bayley, Mark; Rolfe, Danielle

    2011-08-01

    Understanding how to structure educational interventions and resources to facilitate physical therapists' application of the research literature is required. The objective of this study was to explore physical therapists' preferences for strategies to facilitate their access to, evaluation and implementation of the stroke research literature in clinical practice. In-depth, qualitative telephone interviews were conducted with 23 physical therapists who treat people with stroke in Ontario, Canada and who had participated in a previous survey on evidence-based practice. Data were analysed using a constant comparative approach to identify emergent themes. Participants preferred online access to research summaries or systematic reviews to save time to filter and critique research articles. To enable access in the workplace, an acceptable computer-to-staff ratio, permission to access web sites and protected work time were suggested. Participants considered personal digital assistants as excellent tools for quick access to online resources but were unsure of their advantage over a desktop computer. Therapists favoured use of non-technical language, glossaries of research terms and quality ratings of studies to ease understanding and appraisal. Teleconferencing or videoconferencing overcame geographical but not scheduling barriers to accessing education. To achieve behaviour change in clinical practice, therapists preferred multiple interactive, face-to-face education sessions in a group format, with opportunities for case-based learning and practice of new skills. Physical therapists prefer technology-assisted access to resources and education and favour attending multiple interactive, expert-facilitated education sessions incorporating opportunities for case-based learning and practice of new skills to change behaviour related to evidence-based practice. © 2010 Blackwell Publishing Ltd.

  18. Techniques for trans-catheter retrieval of embolized Nit-Occlud® PDA-R and ASD-R devices.

    Science.gov (United States)

    Sinha, Sanjay; Levi, Daniel; Peirone, Alejandro; Pedra, Carlos

    2018-02-15

    Nit-Occlud ® (atrial septal defect) ASD-R and (patent ductus arteriosus) PDA-R devices are used outside the United States for percutaneous closure of the patent ductus arteriosus and atrial septal defects. When embolization occurs, these devices have been difficult to retrieve. Bench simulations of retrieval of PDA-R and ASD-R devices were performed in a vascular model. Retrieval of each device was attempted using snare techniques or with bioptome forceps with a range of devices. The same devices were then intentionally embolized in an animal model. Retrieval methods were systematically tested in a range of sheath sizes, and graded in terms of difficulty and retrieval time. Devices that were grasped by the bioptome in the center of the proximal part of the devices were easily retrieved in both models. Bench studies determined the minimum sheath sizes needed for retrieval of each device with this method. In general sheathes two french sizes greater than the delivery sheath were successful with this technique. Three out of the four PDA-R devices were successfully retrieved in vivo. Two were retrieved by grasping the middle of the PA end of the PDA-R device with a Maslanka bioptome and one small PDA-R device was retrieved using a 10 mm Snare. Four of the five ASD-R devices were retrieved successfully grasping the right atrial ASD-R disc or by passing a wire through the device and snaring this loop. For ASD-R 28 and 30 mm devices, a double bioptome technique was needed to retrieve the device. ASD-R and PDA-R devices can be successfully retrieved in the catheterization lab. It is critical to grab the center portion of the right atrial disc of the ASD-R device or pulmonary portion of the PDA-R device and to use adequately sized sheathes. © 2018 Wiley Periodicals, Inc.

  19. Monitor portátil de signos vitales con un PDA

    OpenAIRE

    Rodríguez Salazar, Rita Beatriz

    2007-01-01

    El monitor portátil de signos vitales facilita el proceso de medición y lleva un registro organizado de los valores medidos. Los signos vitales que se contempla son la temperatura corporal, la presión arterial y la frecuencia cardiaca.Para la medición de estos signos vitales se utilizan los sensores respectivos y se realiza el acondicionamiento de señal. Estas señales son procesadas en un PDA en el que también se visualiza los valores obtenidos en la medición y se registra estos datos si el u...

  20. LC/PDA/ESI-MS Profiling and Radical Scavenging Activity of Anthocyanins in Various Berries

    Directory of Open Access Journals (Sweden)

    Jun-ichiro Nakajima

    2004-01-01

    Full Text Available Anthocyanin extracts of two blueberries, Vaccinium myrtillus (bilberry and Vaccinium ashei (rabbiteye blueberry, and of three other berries, Ribes nigrum (black currant, Aronia melanocarpa (chokeberry, and Sambucus nigra (elderberry, were analyzed by high-performance liquid chromatography coupled with photodiode array detection and electrospray ionization - mass spectrometry (LC/PDA/ESI-MS. Both bilberry and rabbiteye blueberry contained 15 identical anthocyanins with different distribution patterns. Black currant, chokeberry, and elderberry contained 6, 4, and 4 kinds of anthocyanins, respectively. The radical scavenging activities of these berry extracts were analyzed by using 2,2-diphenyl-1-picrylhydrazyl (DPPH. All these extracts showed potent antiradical activities.

  1. Assessment of the Influence Factors on Nasal Spray Droplet Velocity Using Phase-Doppler Anemometry (PDA)

    OpenAIRE

    Liu, Xiaofei; Doub, William H.; Guo, Changning

    2011-01-01

    Droplet velocity is an important parameter that can be used to characterize nasal spray products. In this study, a phase-Doppler anemometry (PDA) system was used to measure the droplet velocities of nasal sprays. A survey of seven commercial nasal spray products showed a range of droplet velocities from 6.7 to 19.2 m/s, all significantly different from each other. A three-level, four-factor Box–Behnken design of experiments (DOE) methodology were applied to investigate the influences of actua...

  2. Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS

    OpenAIRE

    Joshi, Payal; Bhoir, Suvarna; Bhagwat, A. M.; Vishwanath, K.; Jadhav, R. K.

    2011-01-01

    Degradation products of itopride formed under different forced conditions have been identified using LC-PDA and LC-MS techniques. Itopride was subjected to forced degradation under the conditions of hydrolysis, photolysis, oxidation, dry and wet heat, in accordance with the International Conference on Harmonization. The stress solutions were chromatographed on reversed phase C18 (250×4.6 mm, 5 μm) column with a mobile phase methanol:water (55:45, v/v) at a detection wavelength of 215 nm. Itop...

  3. Representação iterativa e folksonomia assistida para repositórios digitais | Iterative representation and folksonomy assisted for digital repositories

    Directory of Open Access Journals (Sweden)

    José Eduardo Santarém Segundo

    2011-03-01

    layer iterative, which allows feedback information, and semantic retrieval of information, through the structural model designed for repositories. The suggested model resulted in the formulation of the thesis that through Iterative Representation it is possible to establish a process of semantic retrieval of information in digital repositories. Keywords digital repositories; iterative representation; folksonomy; folksonomy assisted; semantic web; information retrieval; ontology

  4. LC-MS characterization of valsartan degradation products and comparison with LC-PDA

    Directory of Open Access Journals (Sweden)

    Sumaia Araújo Pires

    2015-12-01

    Full Text Available abstract Valsartan was submitted to forced degradation under acid hydrolysis condition as prescribed by the ICH. Degraded sample aliquots were separated via HPLC using a Hypersil ODS (C18 column (250 x 4.6 mm i.d., 5 µm. Either photodiode array (PDA detection or mass spectrometry (MS full scan monitoring of HPLC runs were used. HPLC-PDA failed to indicate Valsartan degradation under forced acid degradation, showing an insignificant peak area variation and that Valsartan apparently remained pure. HPLC-MS using electrospray ionization (ESI and total ionic current (TIC monitoring did not reveal any peak variation either, but inspection of the ESI mass spectra showed the appearance of m/z 306 and m/z 352 ions for the same retention time as that of Valsartan (m/z 436. These ions were identified as being protonated molecules of two co-eluting degradation products formed by hydrolysis. These assignments were confirmed by ESI-MS/MS with direct infusion of the degraded samples. The results showed that the use of selective HPLC-MS is essential for monitoring Valsartan degradation. Efficient HPLC separation coupled to selective and structural diagnostic MS monitoring seems therefore mandatory for comprehensive drug degradation studies, particularly for new drugs and formulations, and for method development.

  5. Evaluation of axial pile bearing capacity based on pile driving analyzer (PDA) test using Neural Network

    Science.gov (United States)

    Maizir, H.; Suryanita, R.

    2018-01-01

    A few decades, many methods have been developed to predict and evaluate the bearing capacity of driven piles. The problem of the predicting and assessing the bearing capacity of the pile is very complicated and not yet established, different soil testing and evaluation produce a widely different solution. However, the most important thing is to determine methods used to predict and evaluate the bearing capacity of the pile to the required degree of accuracy and consistency value. Accurate prediction and evaluation of axial bearing capacity depend on some variables, such as the type of soil, diameter, and length of pile, etc. The aims of the study of Artificial Neural Networks (ANNs) are utilized to obtain more accurate and consistent axial bearing capacity of a driven pile. ANNs can be described as mapping an input to the target output data. The method using the ANN model developed to predict and evaluate the axial bearing capacity of the pile based on the pile driving analyzer (PDA) test data for more than 200 selected data. The results of the predictions obtained by the ANN model and the PDA test were then compared. This research as the neural network models give a right prediction and evaluation of the axial bearing capacity of piles using neural networks.

  6. Developing digital forensic governance

    CSIR Research Space (South Africa)

    Grobler, M

    2010-03-01

    Full Text Available This paper presents a Digital Forensic (DF) governance framework and its mapping on the SANS ISO/IEC 38500:2009 Corporate governance of information technology structure. DF governance assists organisations in guiding the management team...

  7. Digital signature feasibility study

    Science.gov (United States)

    2008-06-01

    The purpose of this study was to assess the advantages and disadvantages of using digital signatures to assist the Arizona Department of Transportation in conducting business. The Department is evaluating the potential of performing more electronic t...

  8. Mn2+-coordinated PDA@DOX/PLGA nanoparticles as a smart theranostic agent for synergistic chemo-photothermal tumor therapy

    Directory of Open Access Journals (Sweden)

    Xi J

    2017-04-01

    Full Text Available Juqun Xi,1–3 Lanyue Da,1 Changshui Yang,1 Rui Chen,4 Lizeng Gao,2 Lei Fan,5 Jie Han5 1Pharmacology Department, Medical School, Yangzhou University, 2Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile Diseases, 3Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, 4Department of Nephrology, Subei People’s Hospital, Yangzhou University, 5School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, People’s Republic of China Abstract: Nanoparticle drug delivery carriers, which can implement high performances of multi-functions, are of great interest, especially for improving cancer therapy. Herein, we reported a new approach to construct Mn2+-coordinated doxorubicin (DOX-loaded poly(lactic-co-glycolic acid (PLGA nanoparticles as a platform for synergistic chemo-photothermal tumor therapy. DOX-loaded PLGA (DOX/PLGA nanoparticles were first synthesized through a double emulsion-solvent evaporation method, and then modified with polydopamine (PDA through self-polymerization of dopamine, leading to the formation of PDA@DOX/PLGA nanoparticles. Mn2+ ions were then coordinated on the surfaces of PDA@DOX/PLGA to obtain Mn2+-PDA@DOX/PLGA nanoparticles. In our system, Mn2+-PDA@DOX/PLGA nanoparticles could destroy tumors in a mouse model directly, by thermal energy deposition, and could also simulate the chemotherapy by thermal-responsive delivery of DOX to enhance tumor therapy. Furthermore, the coordination of Mn2+ could afford the high magnetic resonance (MR imaging capability with sensitivity to temperature and pH. The results demonstrated that Mn2+-PDA@DOX/PLGA nanoparticles had a great potential as a smart theranostic agent due to their imaging and tumor-growth-inhibition properties. Keywords: PLGA nanoparticles, polydopamine, chemo-photothermal therapy, smart theranostic agent

  9. Evaluation of PDA Technical Report No 33. Statistical Testing Recommendations for a Rapid Microbiological Method Case Study.

    Science.gov (United States)

    Murphy, Thomas; Schwedock, Julie; Nguyen, Kham; Mills, Anna; Jones, David

    2015-01-01

    New recommendations for the validation of rapid microbiological methods have been included in the revised Technical Report 33 release from the PDA. The changes include a more comprehensive review of the statistical methods to be used to analyze data obtained during validation. This case study applies those statistical methods to accuracy, precision, ruggedness, and equivalence data obtained using a rapid microbiological methods system being evaluated for water bioburden testing. Results presented demonstrate that the statistical methods described in the PDA Technical Report 33 chapter can all be successfully applied to the rapid microbiological method data sets and gave the same interpretation for equivalence to the standard method. The rapid microbiological method was in general able to pass the requirements of PDA Technical Report 33, though the study shows that there can be occasional outlying results and that caution should be used when applying statistical methods to low average colony-forming unit values. Prior to use in a quality-controlled environment, any new method or technology has to be shown to work as designed by the manufacturer for the purpose required. For new rapid microbiological methods that detect and enumerate contaminating microorganisms, additional recommendations have been provided in the revised PDA Technical Report No. 33. The changes include a more comprehensive review of the statistical methods to be used to analyze data obtained during validation. This paper applies those statistical methods to analyze accuracy, precision, ruggedness, and equivalence data obtained using a rapid microbiological method system being validated for water bioburden testing. The case study demonstrates that the statistical methods described in the PDA Technical Report No. 33 chapter can be successfully applied to rapid microbiological method data sets and give the same comparability results for similarity or difference as the standard method. © PDA, Inc

  10. Retail Visual Assistant Digital Artefact

    OpenAIRE

    Knott, Neville

    2013-01-01

    Window display, store layout and visual merchandising are defined as the ability to attract and sell to the consumer silently. One of the biggest challenges facing small retail businesses in towns and villages around the globe is how to compete against large multinationals in the visual layout and presentation of their merchandise and shops. One of the key advantages that large retail units have over small ones is professionally merchandised stock incorporated into a strategic spatial layout....

  11. Identification of Forced Degradation Products of Itopride by LC-PDA and LC-MS.

    Science.gov (United States)

    Joshi, Payal; Bhoir, Suvarna; Bhagwat, A M; Vishwanath, K; Jadhav, R K

    2011-05-01

    Degradation products of itopride formed under different forced conditions have been identified using LC-PDA and LC-MS techniques. Itopride was subjected to forced degradation under the conditions of hydrolysis, photolysis, oxidation, dry and wet heat, in accordance with the International Conference on Harmonization. The stress solutions were chromatographed on reversed phase C18 (250×4.6 mm, 5 μm) column with a mobile phase methanol:water (55:45, v/v) at a detection wavelength of 215 nm. Itopride degraded in acid, alkali and oxidative stress conditions. The stability indicating method was developed and validated. The degradation pathway of the drug to products II-VIII is proposed.

  12. Becoming digital

    DEFF Research Database (Denmark)

    Pors, Anja Svejgaard

    2015-01-01

    government, and draws on empirical material generated through observations, field notes, interviews and policy documents. The material is documenting how service is performed by frontline agents in the ‘bureaucratic encounter’ with citizens, who needs assistance to use digital self-service in order to apply...... online for a public benefit. Findings: The paper shows that e-government technology changes the mode of professionalism in citizen service from service to support. The paper gives an empirical account of recent Danish digital reforms and shows how the reforms both enable and constrain the work...... of ‘becoming digital’ by frontline agents. Overall the street-level bureaucrat’s classical tasks such as specialized casework are being displaced into promoting and educational tasks. An implication of this is blurred distinctions between professional skills and personal competences of the frontline agent...

  13. Intelligent speed adaptation as an assistive device for drivers with acquired brain injury

    DEFF Research Database (Denmark)

    Klarborg, Brith; Lahrmann, Harry Spaabæk; Agerholm, Niels

    2012-01-01

    Intelligent speed adaptation (ISA) was tested as an assistive device for drivers with an acquired brain injury (ABI). The study was part of the “Pay as You Speed” project (PAYS) and used the same equipment and technology as the main study (Lahrmann et al., in press-a, in press-b). Two drivers......, and in general they described driving with ISA as relaxed. ISA reduced the percentage of the total distance that was driven with a speed above the speed limit (PDA), but the subjects relapsed to their previous PDA level in Baseline 2. This suggests that ISA is more suited as a permanent assistive device (i...

  14. Digital broadcasting

    International Nuclear Information System (INIS)

    Park, Ji Hyeong

    1999-06-01

    This book contains twelve chapters, which deals with digitization of broadcast signal such as digital open, digitization of video signal and sound signal digitization of broadcasting equipment like DTPP and digital VTR, digitization of equipment to transmit such as digital STL, digital FPU and digital SNG, digitization of transmit about digital TV transmit and radio transmit, digital broadcasting system on necessity and advantage, digital broadcasting system abroad and Korea, digital broadcasting of outline, advantage of digital TV, ripple effect of digital broadcasting and consideration of digital broadcasting, ground wave digital broadcasting of DVB-T in Europe DTV in U.S.A and ISDB-T in Japan, HDTV broadcasting, satellite broadcasting, digital TV broadcasting in Korea, digital radio broadcasting and new broadcasting service.

  15. Temporary Shell Proof-of-Concept Technique: Digital-Assisted Workflow to Enable Customized Immediate Function in Two Visits in Partially Edentulous Patients

    Science.gov (United States)

    Pozzi, Alessandro; Arcuri, Lorenzo; Moy, Peter K

    2018-03-01

    The growing interest in minimally invasive implant placement and delivery of a prefabricated provisional prosthesis immediately, thus minimizing "time to teeth," has led to the development of numerous 3-dimensional (3D) planning software programs. Given the enhancements associated with fully digital workflows, such as better 3D soft-tissue visualization and virtual tooth rendering, computer-guided implant surgery and immediate function has become an effective and reliable procedure. This article describes how modern implant planning software programs provide a comprehensive digital platform that enables efficient interplay between the surgical and restorative aspects of implant treatment. These new technologies that streamline the overall digital workflow allow transformation of the digital wax-up into a personalized, CAD/CAM-milled provisional restoration. Thus, collaborative digital workflows provide a novel approach for time-efficient delivery of a customized, screw-retained provisional restoration on the day of implant surgery, resulting in improved predictability for immediate function in the partially edentate patient.

  16. LC-PDA-ESI/MS Identification of the Phenolic Components of Three Compositae Spices: Chamomile, Tarragon, and Mexican Arnica

    Science.gov (United States)

    Chamomile (Matricaria chamomilla L.), tarragon (Artemisia dracunculus L.) and Mexican arnica (Heterotheca inuoides) are common compositae spices and herbs found in the US market. They contain flavonoids and hydroxycinnamates that are potentially beneficial to human health. A standardized LC-PDA-ESI...

  17. Failure of a repeat course of cyclooxygenase inhibitor to close a PDA is a risk factor for developing chronic lung disease in ELBW infants

    Directory of Open Access Journals (Sweden)

    Adrouche-Amrani Lynda

    2012-01-01

    Full Text Available Abstract Background The optimal treatment regimen or protocol for managing a persistent patent ductus arteriosus (PDA in extremely low birth weight (ELBW infants has not been well established. This study was aimed at evaluating the failure rate of a cyclooxygenase (COX inhibitor (COI for PDA closure and to determine the incidence of a PDA requiring ligation in ELBW infants. We examined the clinical characteristics and risk factors that may predict the clinical consequences of failure of PDA closure by COI. Methods Medical information on 138 infants with birth weight (BW 48 hours was retrieved. Clinical characteristics and outcomes of patients whose PDAs closed with COI were compared with those who did not close. Results Of the 138 patients, 112 survived to discharge. Eighty (71.4% of those who survived received 1-3 courses of COI treatment for a symptomatic PDA. A total of 32 (40% failed COI treatment and underwent PDA ligation. Multivariable logistic regression analysis suggests that the observed differences in the outcomes in infants with or without symptomatic PDA can be explained by the babies with symptomatic PDA being more immature and sicker. No significant difference was seen in the incidence of chronic lung disease (CLD in infants whose PDA was treated medically versus those who failed medical treatment and then underwent ligation. However, after adjusting for disease severity and other known risk factors, the odds ratio of developing CLD for surviving babies with a persistent PDA compared to those whose PDA was successfully closed with 1-2 courses of COI is 3.24 (1.07-9.81; p = 0.038. Conclusions When successfully treated, PDA in ELBW infants did not contribute significantly to the adverse outcomes such as CLD, retinopathy of prematurity (ROP and age at discharge. This suggests that it is beneficial for a hemodynamically significant PDA to be closed. The failure of a repeat course of COI to close a PDA is a major risk factor for

  18. Digital Image Analysis of Yeast Single Cells Growing in Two Different Oxygen Concentrations to Analyze the Population Growth and to Assist Individual-Based Modeling.

    Science.gov (United States)

    Ginovart, Marta; Carbó, Rosa; Blanco, Mónica; Portell, Xavier

    2017-01-01

    Nowadays control of the growth of Saccharomyces to obtain biomass or cellular wall components is crucial for specific industrial applications. The general aim of this contribution is to deal with experimental data obtained from yeast cells and from yeast cultures to attempt the integration of the two levels of information, individual and population, to progress in the control of yeast biotechnological processes by means of the overall analysis of this set of experimental data, and to assist in the improvement of an individual-based model, namely, INDISIM- Saccha . Populations of S. cerevisiae growing in liquid batch culture, in aerobic and microaerophilic conditions, were studied. A set of digital images was taken during the population growth, and a protocol for the treatment and analyses of the images obtained was established. The piecewise linear model of Buchanan was adjusted to the temporal evolutions of the yeast populations to determine the kinetic parameters and changes of growth phases. In parallel, for all the yeast cells analyzed, values of direct morphological parameters, such as area, perimeter, major diameter, minor diameter, and derived ones, such as circularity and elongation, were obtained. Graphical and numerical methods from descriptive statistics were applied to these data to characterize the growth phases and the budding state of the yeast cells in both experimental conditions, and inferential statistical methods were used to compare the diverse groups of data achieved. Oxidative metabolism of yeast in a medium with oxygen available and low initial sugar concentration can be taken into account in order to obtain a greater number of cells or larger cells. Morphological parameters were analyzed statistically to identify which were the most useful for the discrimination of the different states, according to budding and/or growth phase, in aerobic and microaerophilic conditions. The use of the experimental data for subsequent modeling work was then

  19. Comparison on extraction yield of sennoside A and sennoside B from senna (Cassia angustifolia) using conventional and non conventional extraction techniques and their quantification using a validated HPLC-PDA detection method.

    Science.gov (United States)

    Dhanani, Tushar; Singh, Raghuraj; Reddy, Nagaraja; Trivedi, A; Kumar, Satyanshu

    2017-05-01

    Senna is an important medicinal plant and is used in many Ayurvedic formulations. Dianthraquinone glucosides are the main bioactive phytochemicals present in leaves and pods of senna. The extraction efficiency in terms of yield and composition of the extract of senna prepared using both conventional (cold percolation at room temperature and refluxing) and non conventional (ultrasound and microwave assisted solvent extraction as well as supercritical fluid extraction) techniques were compared in the present study. Also a rapid reverse phase HPLC-PDA detection method was developed and validated for the simultaneous determination of sennoside A and sennoside B in the different extracts of senna leaves. Ultrasound and microwave assisted solvent extraction techniques were more effective in terms of yield and composition of the extracts compared to cold percolation at room temperature and refluxing methods of extraction.

  20. Testing of complementarity of PDA and MS detectors using chromatographic fingerprinting of genuine and counterfeit samples containing sildenafil citrate.

    Science.gov (United States)

    Custers, Deborah; Krakowska, Barbara; De Beer, Jacques O; Courselle, Patricia; Daszykowski, Michal; Apers, Sandra; Deconinck, Eric

    2016-02-01

    Counterfeit medicines are a global threat to public health. High amounts enter the European market, which is why characterization of these products is a very important issue. In this study, a high-performance liquid chromatography-photodiode array (HPLC-PDA) and high-performance liquid chromatography-mass spectrometry (HPLC-MS) method were developed for the analysis of genuine Viagra®, generic products of Viagra®, and counterfeit samples in order to obtain different types of fingerprints. These data were included in the chemometric data analysis, aiming to test whether PDA and MS are complementary detection techniques. The MS data comprise both MS1 and MS2 fingerprints; the PDA data consist of fingerprints measured at three different wavelengths, i.e., 254, 270, and 290 nm, and all possible combinations of these wavelengths. First, it was verified if both groups of fingerprints can discriminate between genuine, generic, and counterfeit medicines separately; next, it was studied if the obtained results could be ameliorated by combining both fingerprint types. This data analysis showed that MS1 does not provide suitable classification models since several genuines and generics are classified as counterfeits and vice versa. However, when analyzing the MS1_MS2 data in combination with partial least squares-discriminant analysis (PLS-DA), a perfect discrimination was obtained. When only using data measured at 254 nm, good classification models can be obtained by k nearest neighbors (kNN) and soft independent modelling of class analogy (SIMCA), which might be interesting for the characterization of counterfeit drugs in developing countries. However, in general, the combination of PDA and MS data (254 nm_MS1) is preferred due to less classification errors between the genuines/generics and counterfeits compared to PDA and MS data separately.

  1. Percutaneous closure of patent ductus arteriosus in children using amplatzer duct occluder II: relationship between PDA type and risk of device protrusion into the descending aorta.

    Science.gov (United States)

    Masri, Samer; El Rassi, Issam; Arabi, Mariam; Tabbakh, Anas; Bitar, Fadi

    2015-08-01

    To compare the efficacy and safety of Amplatzer Duct Occluder II (ADOII) among the various patent ductus arteriosus (PDA) types, and to assess the association between development of aortic obstruction and the PDA type in terms of measurable parameters as the device angulation and distance of upper end protrusion into the aortic lumen. Retrospective cohort study involving 50 consecutive subjects who underwent ADO II device closure of PDA. The median age and weight at intervention were 13 months (5.5 months to 18 years) and 11 (6-67) kg respectively. The median smallest ductal diameter by angiography was 3.2 (1.9-5.4) mm. Thirty two patients had type A PDA, 5 had type C, 5 had type D, and 8 had type E. Residual shunt was seen in only 1 patient who had a tubular PDA and resolved within 2 months of the procedure. No device embolization or pulmonary side protrusion were noted. There was a 16% aortic protrusion rate. The median distance of protrusion of the upper end of the device into the aortic lumen was 3.1 (0-9) mm and the median angle formed between the aortic end of the device and the PDA take-off was 10.4 (0-80.6) degrees. These latter parameters of aortic obstruction were significantly higher in the non-conical PDA group as compared to the conical PDA. Nevertheless, there was no significant coarctation due to aortic retention disc protrusion. Device closure of PDA using the ADO II is a safe procedure for chosen types of PDA. We demonstrated a novel technique for objective assessment of device protrusion into the descending aorta based on measurable parameters. ADOII device closure of non-conical PDAs warrants closer follow ups. © 2015 Wiley Periodicals, Inc.

  2. Digital disruption ?syndromes.

    Science.gov (United States)

    Sullivan, Clair; Staib, Andrew

    2017-05-18

    The digital transformation of hospitals in Australia is occurring rapidly in order to facilitate innovation and improve efficiency. Rapid transformation can cause temporary disruption of hospital workflows and staff as processes are adapted to the new digital workflows. The aim of this paper is to outline various types of digital disruption and some strategies for effective management. A large tertiary university hospital recently underwent a rapid, successful roll-out of an integrated electronic medical record (EMR). We observed this transformation and propose several digital disruption "syndromes" to assist with understanding and management during digital transformation: digital deceleration, digital transparency, digital hypervigilance, data discordance, digital churn and post-digital 'depression'. These 'syndromes' are defined and discussed in detail. Successful management of this temporary digital disruption is important to ensure a successful transition to a digital platform. What is known about this topic? Digital disruption is defined as the changes facilitated by digital technologies that occur at a pace and magnitude that disrupt established ways of value creation, social interactions, doing business and more generally our thinking. Increasing numbers of Australian hospitals are implementing digital solutions to replace traditional paper-based systems for patient care in order to create opportunities for improved care and efficiencies. Such large scale change has the potential to create transient disruption to workflows and staff. Managing this temporary disruption effectively is an important factor in the successful implementation of an EMR. What does this paper add? A large tertiary university hospital recently underwent a successful rapid roll-out of an integrated electronic medical record (EMR) to become Australia's largest digital hospital over a 3-week period. We observed and assisted with the management of several cultural, behavioural and

  3. Evaluation of the content variation of anthraquinone glycosides in rhubarb by UPLC-PDA

    Science.gov (United States)

    2013-01-01

    Background Rhubarb is an important Chinese medicinal herb with a long history of over 2000 years and has been commonly used as a laxative. It is the radix and rhizome of Rheum officinale Baill., R. palmatum L. and R. tanguticum Maxim, all of which are mainly distributed in a broad region in the Tibetan plateau. Anthraquinone glycosides are a series of major active ingredients found in all three species. They are key intermediates in the anthraquinone secondary metabolism and the sennnoside biosynthesis. The variation of the anthraquinone glycoside content in rhubarb in response to specific factors remains an attractive topic. Results A simple and sensitive Ultra Performance Liquid Chromatography with Photo-Diode Array (UPLC-PDA) detector was developed for the simultaneous determination of six anthraquinone glycosides in rhubarb, i.e., aloeemodin-8-O-glucoside, rhein-8-O-glucoside, chrysophanol-1-O-glucoside, emodin-1-O-glucoside, chrysophanol-8-O-glucoside, emodin-8-O-glucoside. Twenty-seven batches from three species were submitted to the multi-component analysis. The results showed that the anthraquinone glycoside content varied significantly even within the same species. The results showed that the anthraquinone glycoside content varied significantly within the same species but not between different species. The PCA and content analysis results confirmed that the plant species has no obvious effect on the content variation. Neither was any significant correlation observed between the anthraquinone glycoside content and the geographic distribution of the rhubarb. Through correlational analysis, altitude was found to be the main factor that affects the anthraquinone glycoside content in rhubarb. Rhubarb grown at higher altitude has higher anthraquinone glycoside content. Conclusions This work provides a rapid, sensitive and accurate UPLC-PDA method for the simultaneous determination of six anthraquinone glycosides in rhubarb. The anthraquinone glycoside content

  4. Black Men and the Digital Divide

    Science.gov (United States)

    Conceição, Simone C. O.; Martin, Larry G.

    2016-01-01

    This chapter focuses on the role adult educators can play in assisting Black men to overcome the challenges faced in accessing and using digital technology and acquiring appropriate skills in a digital society.

  5. Carotenoid composition of jackfruit (Artocarpus heterophyllus), determined by HPLC-PDA-MS/MS.

    Science.gov (United States)

    de Faria, A F; de Rosso, V V; Mercadante, A Z

    2009-06-01

    Carotenoids are pigments responsible for the yellow-reddish color of many foods and are related to important functions and physiological actions, preventing several chronic-degenerative diseases. The objective of this study was to confirm the carotenoid composition of jackfruit by high-performance liquid chromatography connected to photodiode array and mass spectrometry detectors (HPLC-PDA-MS/MS). The main carotenoids were all-trans-lutein (24-44%), all-trans-beta-carotene (24-30%), all-trans-neoxanthin (4-19%), 9-cis-neoxanthin (4-9%) and 9-cis-violaxanthin (4-10%). Either qualitative or quantitative differences, mainly related to the lutein proportion, were found among three batches of jackfruit. Since the fruits from batch A showed significantly lower contents for almost all carotenoids, it also had the lowest total carotenoid content (34.1 microg/100 g) and provitamin A value, whereas the total carotenoid ranged from 129.0 to 150.3 microg/100 g in the other batches. The provitamin A values from batches B and C were 3.3 and 4.3 microg RAE/100 g, respectively. The carotenoid composition of jackfruit was successfully determined, where 14 of the 18 identified carotenoids were reported for first time. Differences among batches may be due to genetic and/or agricultural factors.

  6. Determination of amphotericin B in PLA-PEG blend nanoparticles by HPLC-PDA

    Directory of Open Access Journals (Sweden)

    Caroline Danziato Rodrigues

    2014-12-01

    Full Text Available In this work, we developed and validated an effective reversed-phase HPLC method with photodiode array (PDA detection for the quantitative analysis of amphotericin B (AmB in poly(lactide-poly(ethylene glycol (PLA-PEG blend nanoparticles. Chromatographic runs were performed on a reverse phase C18 column using a mobile phase comprising a 9% acetic acid and acetonitrile mixture (40:60, v/v under isocratic elution with a flow rate of 1 mL/min. AmB was detected at a wavelength of 408 nm. The validation process was performed considering the selectivity, linearity, precision, accuracy, robustness, limit of detection (LOD and limit of quantitation (LOQ of the method. A concentration range of 1-20 µg/mL was used to construct a linear calibration curve. The LOQ and LOD were 55 and 18 ng/mL, respectively. The mean recovery of AmB from the samples was 99.92% (relative standard deviation (RSD = 0.34%, n=9, and the method was robust for changes in the flow rate of the mobile phase (maximum RSD=4.82%. The intra- and inter-assay coefficients of variation were less than 0.59%. The method was successfully used to determine the entrapment efficiency of AmB in PLA-PEG blend nanoparticles.

  7. Computer assisted radiology

    International Nuclear Information System (INIS)

    Lemke, H.U.; Jaffe, C.C.; Felix, R.

    1993-01-01

    The proceedings of the CAR'93 symposium present the 126 oral papers and the 58 posters contributed to the four Technical Sessions entitled: (1) Image Management, (2) Medical Workstations, (3) Digital Image Generation - DIG, and (4) Application Systems - AS. Topics discussed in Session (1) are: picture archiving and communication systems, teleradiology, hospital information systems and radiological information systems, technology assessment and implications, standards, and data bases. Session (2) deals with computer vision, computer graphics, design and application, man computer interaction. Session (3) goes into the details of the diagnostic examination methods such as digital radiography, MRI, CT, nuclear medicine, ultrasound, digital angiography, and multimodality imaging. Session (4) is devoted to computer-assisted techniques, as there are: computer assisted radiological diagnosis, knowledge based systems, computer assisted radiation therapy and computer assisted surgical planning. (UWA). 266 figs [de

  8. The Development of a Patient-Identification-Oriented Nursing Shift Exchange Support System Using Wireless RFID PDA Techniques

    OpenAIRE

    Huang, Pin-Jen; She, Chien-Cheng; Chang, Polun

    2005-01-01

    The objectives of this study were to technically testing the feasibility of combining RFID and PDA technologies in nursing care and to develop a support system for the nursing shift exchange, which featured with “Positive Patient Identification” and “Point of Care” for patient’s safety and security. The most challenging part for the future work would be to embed the system into the real workflow. Future study would be to examine the practical effectiveness of the system....

  9. PubMed Informer: Monitoring MEDLINE/PubMed through E-mail Alerts, SMS, PDA downloads and RSS feeds

    Science.gov (United States)

    Muin, Michael; Fontelo, Paul; Ackerman, Michael

    2005-01-01

    Summary PubMed Informer is a Web-based monitoring tool for topics of interest from MEDLINE/PubMed primarily designed for healthcare professionals. Five tracking methods are available: Web access, e-mail, Short Message Service (SMS), PDA downloads and RSS feeds. PubMed Informer delivers focused search updates and specific information to users with varying information-seeking practices. PMID:16779344

  10. Probabilistic Design Analysis (PDA) Approach to Determine the Probability of Cross-System Failures for a Space Launch Vehicle

    Science.gov (United States)

    Shih, Ann T.; Lo, Yunnhon; Ward, Natalie C.

    2010-01-01

    Quantifying the probability of significant launch vehicle failure scenarios for a given design, while still in the design process, is critical to mission success and to the safety of the astronauts. Probabilistic risk assessment (PRA) is chosen from many system safety and reliability tools to verify the loss of mission (LOM) and loss of crew (LOC) requirements set by the NASA Program Office. To support the integrated vehicle PRA, probabilistic design analysis (PDA) models are developed by using vehicle design and operation data to better quantify failure probabilities and to better understand the characteristics of a failure and its outcome. This PDA approach uses a physics-based model to describe the system behavior and response for a given failure scenario. Each driving parameter in the model is treated as a random variable with a distribution function. Monte Carlo simulation is used to perform probabilistic calculations to statistically obtain the failure probability. Sensitivity analyses are performed to show how input parameters affect the predicted failure probability, providing insight for potential design improvements to mitigate the risk. The paper discusses the application of the PDA approach in determining the probability of failure for two scenarios from the NASA Ares I project

  11. Business Planning for Cultural Heritage Institutions. A Framework and Resource Guide to Assist Cultural Heritage Institutions with Business Planning for Sustainability of Digital Asset Management Programs

    Science.gov (United States)

    Bishoff, Liz; Allen, Nancy

    2004-01-01

    The purpose of this document is to present a framework and resource guide to help cultural heritage institutions plan sustainable access to their digital cultural assets and to do so by means that link their missions to planning modes and models. To aid cultural heritage organizations in the business-planning process, this resource will do the…

  12. SHDAS Production Digitizer Evaluation.

    Energy Technology Data Exchange (ETDEWEB)

    Merchant, Bion J. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2017-07-01

    The Seismo-Hydroacoustic Data Acquisition System (SHDAS) is undergoing evaluation in preparation for its engineering, development, and deployment by the U.S Navy as an ocean bottom seismic monitoring system. At the current stage of development, the production digitizers are being evaluated to confirm their performance prior to packaging and assembly for deployment. The testing of the digitizers is being conducted at Delta Group Electronics, the digitizer fabricator, in San Diego, California, performed by Sandia National Laboratories with the assistance of Leidos and Delta Group Electronics.

  13. WE-A-17A-03: Catheter Digitization in High-Dose-Rate Brachytherapy with the Assistance of An Electromagnetic (EM) Tracking System

    Energy Technology Data Exchange (ETDEWEB)

    Damato, AL; Bhagwat, MS; Buzurovic, I; Devlin, PM; Friesen, S; Hansen, JL; Kapur, T; Lee, LJ; Mehrtash, A; Nguyen, PL; O' Farrell, D; Wang, W; Viswanathan, AN; Cormack, RA [Brigham and Women' s Hospital, Boston, MA (United States)

    2014-06-15

    Purpose: To investigate the use of a system using EM tracking, postprocessing and error-detection algorithms for measuring brachytherapy catheter locations and for detecting errors and resolving uncertainties in treatment-planning catheter digitization. Methods: An EM tracker was used to localize 13 catheters in a clinical surface applicator (A) and 15 catheters inserted into a phantom (B). Two pairs of catheters in (B) crossed paths at a distance <2 mm, producing an undistinguishable catheter artifact in that location. EM data was post-processed for noise reduction and reformatted to provide the dwell location configuration. CT-based digitization was automatically extracted from the brachytherapy plan DICOM files (CT). EM dwell digitization error was characterized in terms of the average and maximum distance between corresponding EM and CT dwells per catheter. The error detection rate (detected errors / all errors) was calculated for 3 types of errors: swap of two catheter numbers; incorrect catheter number identification superior to the closest position between two catheters (mix); and catheter-tip shift. Results: The averages ± 1 standard deviation of the average and maximum registration error per catheter were 1.9±0.7 mm and 3.0±1.1 mm for (A) and 1.6±0.6 mm and 2.7±0.8 mm for (B). The error detection rate was 100% (A and B) for swap errors, mix errors, and shift >4.5 mm (A) and >5.5 mm (B); errors were detected for shifts on average >2.0 mm (A) and >2.4 mm (B). Both mix errors associated with undistinguishable catheter artifacts were detected and at least one of the involved catheters was identified. Conclusion: We demonstrated the use of an EM tracking system for localization of brachytherapy catheters, detection of digitization errors and resolution of undistinguishable catheter artifacts. Automatic digitization may be possible with a registration between the imaging and the EM frame of reference. Research funded by the Kaye Family Award 2012.

  14. Promoting Real-Time Science in the Classroom using Wireless PDA Technology

    Science.gov (United States)

    Matusow, David; Sparmo, Joe; Weidow, Dave; Obenschain, Arthur F. (Technical Monitor)

    2002-01-01

    The year is 2004, NASA has landed and deployed a fleet of rovers on the surface of Mars to continue the exploration of that planet and prepare the way for human visitors. Middle school students at Milton Elementary have been following the mission through the media and Internet as part of Mr. Johnson's Earth and space sciences class. The kids have been working in teams to track the rovers as they move across the surface of Mars on a scale model of the landing site they built from sand and rocks using pictures and video downloaded from the Internet. They also built their own version of a rover that can be driven around the model. The time is 3:36pm. Jim and a couple of his fellow students from class are sitting in the cafeteria waiting for a student council meeting to begin. Mary and several others are on the bus riding home. Kathy is in her father's car waiting to leave the parking lot. On Mars, Rover-3 has just stopped and issued an alert to ground control at NASA's Jet Propulsion Laboratory (JPL). Back at Milton Elementary chimes can be heard going off in the cafeteria, on the school bus, and in Kathy's car. The students are familiar with the drill and each brings up the Mars mission status display on their hand-held PDA device. They've been using their PDAs (those Palm devices that seem to be everywhere today) to obtain real-time position information for each of the rovers throughout the mission. The mission status display tells them that Rover-3 has stopped on the edge of a small gully and isn't quite sure what to do. The students begin considering the options amongst themselves. Should the rover just drive through the gully? If it does, what happens if it gets stuck? Maybe it should turnaround and look for away around the gully? Trough questions. Real questions. Real problems. The students know they will need to be prepared to discuss the options and conduct their own simulations using the models they built in Mr. Johnson's class tomorrow. Much the same way

  15. Human placenta-derived cells (PDA-001) for the treatment of adults with multiple sclerosis: a randomized, placebo-controlled, multiple-dose study.

    Science.gov (United States)

    Lublin, Fred D; Bowen, James D; Huddlestone, John; Kremenchutzky, Marcelo; Carpenter, Adam; Corboy, John R; Freedman, Mark S; Krupp, Lauren; Paulo, Corri; Hariri, Robert J; Fischkoff, Steven A

    2014-11-01

    Infusion of PDA-001, a preparation of mesenchymal-like cells derived from full-term human placenta, is a new approach in the treatment of patients with multiple sclerosis. This safety study aimed to rule out the possibility of paradoxical exacerbation of disease activity by PDA-001 in patients with multiple sclerosis. This was a phase 1b, multicenter, randomized, double-blind, placebo-controlled, 2-dose ranging study including patients with relapsing-remitting multiple sclerosis or secondary progressive multiple sclerosis. The study was conducted at 6 sites in the United States and 2 sites in Canada. Patients were randomized 3:1 to receive 2 low-dose infusions of PDA-001 (150×10(6) cells) or placebo, given 1 week apart. After completing this cohort, subsequent patients received high-dose PDA-001 (600×10(6) cells) or placebo. Monthly brain magnetic resonance imaging scans were performed. The primary end point was ruling out the possibility of paradoxical worsening of MS disease activity. This was monitored using Cutter׳s rule (≥5 new gadolinium lesions on 2 consecutive scans) by brain magnetic resonance imaging on a monthly basis for six months and also the frequency of multiple sclerosis relapse. Ten patients with relapsing-remitting multiple sclerosis and 6 with secondary progressive multiple sclerosis were randomly assigned to treatment: 6 to low-dose PDA-001, 6 to high-dose PDA-001, and 4 to placebo. No patient met Cutter׳s rule. One patient receiving high-dose PDA-001 had an increase in T2 and gadolinium lesions and in Expanded Disability Status Scale score during a multiple sclerosis flare 5 months after receiving PDA-001. No other patient had an increase in Expanded Disability Status Scale score>0.5, and most had stable or decreasing Expanded Disability Status Scale scores. With high-dose PDA-001, 1 patient experienced a grade 1 anaphylactoid reaction and 1 had grade 2 superficial thrombophlebitis. Other adverse events were mild to moderate and included

  16. Use of digital Munsell color space to assist interretation of imaging spectrometer data: Geologic examples from the northern Grapevine Mountains, California and Nevada

    Science.gov (United States)

    Kruse, F. A.; Knepper, D. H., Jr.; Clark, R. N.

    1986-01-01

    Techniques using Munsell color transformations were developed for reducing 128 channels (or less) of Airborne Imaging Spectrometer (AIS) data to a single color-composite-image suitable for both visual interpretation and digital analysis. Using AIS data acquired in 1984 and 1985, limestone and dolomite roof pendants and sericite-illite and other clay minerals related to alteration were mapped in a quartz monzonite stock in the northern Grapevine Mountains of California and Nevada. Field studies and laboratory spectral measurements verify the mineralogical distributions mapped from the AIS data.

  17. Application of Hplc-Pda Method Using Two Different Extraction Procedures for the Determination of Alkylresorcinols in Cereals

    Directory of Open Access Journals (Sweden)

    Gailāne Natālija

    2015-09-01

    Full Text Available Cereals, especially barley, are an important source of vitamins, minerals, dietary fibre and various phytochemicals, such as alkylresorcinols (ARs. Cereal ARs are a group of phenolic lipids located in the outer parts of grain, particularly in rye and wheat, but not found in refined flour or in refined products from cereals. This study focuses on the comparison of different extraction procedures applied for the determination of the content of ARs (C15:0 - C23:0 in grain of Latvian barley genotypes. The content of ARs in 1 rye and 16 barley samples grown with different amounts of fertilier was determined by High Performance Liquid Chromatography method with Photodiode Array detection (HPLC-PDA developed by us. Two different extraction methods were compared: accelerated Soxhlet extraction and 24-hour extraction. Aside from validation of the extraction procedures, validation parameters for the HPLC-PDA based quantitation method were provided. The coefficients of variation for repeatability and intermediate precision were < 9% and < 3%, respectively. The content of ARs determined with the HPLC-PDA method in conjunction with accelerated Soxhlet extraction was up to 1.5 times higher than using 24-hour extraction. AR content varied from 2.11 ± 0.04 to 3.80 ± 0.10 mg·100 g-1 for 24-hour extraction and from 2.66 ± 0.06 to 5.70 ± 0.20 mg·100 g-1 for accelerated Soxhlet extraction, indicating the increased efficiency of this procedure in analysis of ARs.

  18. Phytochemical analysis of Vernonanthura tweedieana and a validated UPLC-PDA method for the quantification of eriodictyol

    Directory of Open Access Journals (Sweden)

    Layzon Antonio Lemos da Silva

    Full Text Available AbstractVernonanthura tweedieana (Baker H. Rob., Asteraceae, is used in the Brazilian folk medicine for the treatment of respiratory diseases. In this work the phytochemical investigation of its ethanol extracts as well as the development and validation of an UPLC-PDA method for the quantification of the eriodictyol from the leaves were performed. The phytochemical study for this species lead to the identification of ethyl caffeate, naringenin and chrysoeriol in mixture, eriodictyol from leaves, and the mixture of 3-hydroxy-1-(4-hydroxy-3,5-dimethoxyphenyl-propan-1-one and evofolin B, apigenin, the mixture of caffeic and protocatechuic acid and luteolin from stems with roots, being reported for the first time for V. tweedieana, except for eriodictyol. The structural elucidation of all isolated compounds was achieved by 1H and 2D NMR spectroscopy, and in comparison with published data. An UPLC-PDA method for quantification of the eriodictyol in leaves of V. tweedieana was developed and validated for specificity, linearity, precision (repeatability and intermediate precision, limit of detection (LOD and limit of quantification (LOQ, accuracy and robustness. In this study, an excellent linearity was obtained (r2 = 0.9999, good precision (repeatability RSD = 2% and intermediate precision RSD = 8% and accuracy (average recovery from 98.6% to 99.7%. The content of eriodictyol in the extract of leaves of V. tweedieana was 41.40 ± 0.13 mg/g. Thus, this study allowed the optimization of a simple, fast and validated UPLC-PDA method which can be used to support the quality assessment of this herbal material.

  19. Quantification of patulin in fruit leathers by ultra-high-performance liquid chromatography-photodiode array (UPLC-PDA).

    Science.gov (United States)

    Maragos, Chris M; Busman, Mark; Ma, Liang; Bobell, John

    2015-01-01

    Patulin is a mycotoxin commonly found in certain fruit and fruit products. For this reason many countries have established regulatory limits pertaining to, in particular, apple juice and apple products. Fruit leathers are produced by dehydrating fruit puree, leaving a sweet product that has a leathery texture. A recent report in the literature described the detection of patulin at substantial levels in fruit leathers. To investigate this further, an ultra-high-performance liquid chromatography-photodiode array (UPLC-PDA) method was developed for the sensitive detection of patulin in fruit leathers. Investigations were also made of the suitability of direct analysis in real time-mass spectrometry (DART-MS) for detection of patulin from the surface of fruit leathers. Results indicated DART-MS was insufficiently sensitive for quantification from the surface of home-style apple leathers, although patulin spiked onto the surface of leather or peel could be detected. The UPLC-PDA method was used to determine the fate of patulin during the preparation of home-made fruit leathers. Interestingly, when a home-style process was used, the patulin was not destroyed, but rather increased in concentration as the puree was dehydrated. The UPLC-PDA method was also used to screen for patulin in commercial fruit leathers. Of the 36 products tested, 14 were above the limit of detection (3.5 μg kg(-1)) and nine were above the limit of quantification (12 μg kg(-1)). Positive samples were confirmed by UPLC-MS/MS. Only one sample was found above the US regulatory limit for single-strength apple juice products (50 μg kg(-1)). These results suggest patulin can be concentrated during preparation and can be found in fruit leathers. The limited survey suggests that patulin is fairly prevalent in such commercial products, but that the levels are usually low.

  20. Nonlinear optical switching of PDA/Ag hybrid materials based on temperature- and pH-responsive threading and dethreading of cyclodextrin polypseudorotaxane

    Energy Technology Data Exchange (ETDEWEB)

    Rao, Jinan; Wen, Xiaolei; Leng, Jing; Wang, Jin; Zou, Gang; Zhang, Qijin [University of Science and Technology of China, CAS Key Laboratory of Soft Matter Chemistry, Department of Polymer Science and Engineering, Key Laboratory of Optoelectronic Science and Technology in Anhui Province, Anhui (China)

    2012-11-15

    We developed a novel temperature and pH dual-responsive supramolecular system in which the aggregation and disaggregation of polydiacetylene/silver (PDA/Ag) hybrid nanocrystals can be mediated by environmentally responsive threading and dethreading processes of polypseudorotaxane. The PDA/Ag hybrid nanocrystals provide a nonlinear optical (NLO) property. The host-guest interaction between poly(ethylene glycol) (PEG) and cyclodextrin (CD) cavities on the surface of the hybrid nanocrystals causes the PDA/Ag hybrid nanocrystals to be sufficiently close to each other for providing an enhanced surface plasmon resonance and a corresponding NLO effect. NLO switching of the colloidal materials can be easily realized by varying temperature and pH. The facile preparation procedures and their response to the surrounding media render these novel hybrid colloidal materials potential candidates for applications in sensors, catalysis and optical/electronic devices. (orig.)

  1. Digital radiography

    International Nuclear Information System (INIS)

    Brody, W.R.

    1984-01-01

    Digital Radiography begins with an orderly introduction to the fundamental concepts of digital imaging. The entire X-ray digital imagining system is described, from an overall characterization of image quality to specific components required for a digital radiographic system. Because subtraction is central to digital radiographic systems, the author details the use of various subtraction methods for image enhancement. Complex concepts are illustrated with numerous examples and presented in terms that can readily be understood by physicians without an advanced mathematics background. The second part of the book discusses implementations and applications of digital imagining systems based on area and scanned detector technologies. This section includes thorough coverage of digital fluoroscopy, scanned projection radiography, and film-based digital imaging systems, and features a state-of-the-art synopsis of the applications of digital subtraction angiography. The book concludes with a timely assessment of anticipated technological advances

  2. Origin Discrimination of Osmanthus fragrans var. thunbergii Flowers using GC-MS and UPLC-PDA Combined with Multivariable Analysis Methods.

    Science.gov (United States)

    Zhou, Fei; Zhao, Yajing; Peng, Jiyu; Jiang, Yirong; Li, Maiquan; Jiang, Yuan; Lu, Baiyi

    2017-07-01

    Osmanthus fragrans flowers are used as folk medicine and additives for teas, beverages and foods. The metabolites of O. fragrans flowers from different geographical origins were inconsistent in some extent. Chromatography and mass spectrometry combined with multivariable analysis methods provides an approach for discriminating the origin of O. fragrans flowers. To discriminate the Osmanthus fragrans var. thunbergii flowers from different origins with the identified metabolites. GC-MS and UPLC-PDA were conducted to analyse the metabolites in O. fragrans var. thunbergii flowers (in total 150 samples). Principal component analysis (PCA), soft independent modelling of class analogy analysis (SIMCA) and random forest (RF) analysis were applied to group the GC-MS and UPLC-PDA data. GC-MS identified 32 compounds common to all samples while UPLC-PDA/QTOF-MS identified 16 common compounds. PCA of the UPLC-PDA data generated a better clustering than PCA of the GC-MS data. Ten metabolites (six from GC-MS and four from UPLC-PDA) were selected as effective compounds for discrimination by PCA loadings. SIMCA and RF analysis were used to build classification models, and the RF model, based on the four effective compounds (caffeic acid derivative, acteoside, ligustroside and compound 15), yielded better results with the classification rate of 100% in the calibration set and 97.8% in the prediction set. GC-MS and UPLC-PDA combined with multivariable analysis methods can discriminate the origin of Osmanthus fragrans var. thunbergii flowers. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  3. Engineering a self-driven PVDF/PDA hybrid membranes based on membrane micro-reactor effect to achieve super-hydrophilicity, excellent antifouling properties and hemocompatibility

    Science.gov (United States)

    Li, Jian-Hua; Ni, Xing-Xing; Zhang, De-Bin; Zheng, Hui; Wang, Jia-Bin; Zhang, Qi-Qing

    2018-06-01

    A facile and versatile approach for the preparation of super-hydrophilic, excellent antifouling and hemocompatibility membranes had been developed through the generation in situ of bio-inspired polydopamine (PDA) microspheres on PVDF membranes. SEM images showed that the PDA microspheres were uniformly dispersed on the upper surface and the lower surface of the modified membranes. And there were a great number of PDA microspheres immobilized on the cross-section, but the interconnected pores structure was not destroyed. These facts indicated the existence of membrane micro-reactor effect for the whole membrane structure. Considering the remarkable improvement of hydrophilicity, antifouling properties, and permeation fluxes, we also proposed the cluster phenolic hydroxyl effect for the PVDF/PDA hybrid membranes. And the cluster phenolic hydroxyl effect can be ascribed to the all directions distributed phenolic hydroxyl groups on the whole membrane structure. Besides, the self-driven filtration experiments showed the great wetting ability and permeability of the PVDF/PDA hybrid membranes in filtration process without any external pressure. This implied the existence of accelerating self-driven force after the water flow flowed into the internal of membranes, which contributed to the increase of water flow velocity. All the three aspects were in favor of the enhancement of hydrophilicity, antifouling properties and permeability of the modified membranes. Moreover, the conventional filtration tests, oil/water emulsion filtration tests and protein adsorption tests were also carried out to discuss the practical applications of PVDF/PDA hybrid membranes. And the hemocompatibility of the modified membranes was also proved to enhance greatly through the hemolysis tests and platelet adhesion tests, indicating that the membranes were greatly promising in biomedical applications. The strategy of material modification reported here is substrate-independent and can be extended

  4. Digital Culture and Digital Library

    Directory of Open Access Journals (Sweden)

    Yalçın Yalçınkaya

    2016-12-01

    Full Text Available In this study; digital culture and digital library which have a vital connection with each other are examined together. The content of the research consists of the interaction of culture, information, digital culture, intellectual technologies, and digital library concepts. The study is an entry work to integrity of digital culture and digital library theories and aims to expand the symmetry. The purpose of the study is to emphasize the relation between the digital culture and digital library theories acting intersection of the subjects that are examined. Also the perspective of the study is based on examining the literature and analytical evaluation in both studies (digital culture and digital library. Within this context, the methodology of the study is essentially descriptive and has an attribute for the transmission and synthesis of distributed findings produced in the field of the research. According to the findings of the study results, digital culture is an inclusive term that describes the effects of intellectual technologies in the field of information and communication. Information becomes energy and the spectrum of the information is expanding in the vertical rise through the digital culture. In this context, the digital library appears as a new living space of a new environment. In essence, the digital library is information-oriented; has intellectual technology support and digital platform; is in a digital format; combines information resources and tools in relationship/communication/cooperation by connectedness, and also it is the dynamic face of the digital culture in time and space independence. Resolved with the study is that the digital libraries are active and effective in the formation of global knowing and/or mass wisdom in the process of digital culture.

  5. Resveratrol-Loaded Polymeric Nanoparticles: Validation of an HPLC-PDA Method to Determine the Drug Entrapment and Evaluation of Its Antioxidant Activity

    OpenAIRE

    da Rocha Lindner, Gabriela; Khalil, Najeh Maissar; Mainardes, Rubiana Mara

    2013-01-01

    Poly(lactic acid) (PLA) and PLA-poly(ethylene glycol) (PLA-PEG) nanoparticles containing resveratrol (RVT) were developed, and their antioxidant activity was evaluated. An analytical method using high performance liquid chromatography (HPLC)/photodiode array (PDA) detection was also developed and validated for RVT determination in nanoparticles. The mobile phase consisted of methanol : water (51 : 49, v/v) flowed at 0.9 mL/min, and the PDA detector was set at wavelength of 306 nm. The mean di...

  6. Spectroscopic Studies of a Three-dimensional, Five-coordinated Copper(Ⅱ) Complex via Hydrogen Bonds: [Cu(PDA)(H2O)2](H2PDA=Pyridine-2,6-dicarboxylic Acid)

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    A new copper(Ⅱ) complex [Cu(PDA)(H2O)2] was synthesized and its structure was determined. Cu(Ⅱ) is five-coordinated in a tetragonal pyramid geometry. The two coordinating water molecules are different and the two Cu-O bond lengths differ by nearly 0.02 nm. The whole crystal is linked to form a three-dimensional network by means of hydrogen bonds. The X-band ESR spectrum shows three different g tensors with a well-resolved hyperfine structure in the gz signal, giving the ESR parameters gx=2.05, gy=2.065 and gz=2.29. The covalency of the coordinate bonds and the deviation from tetragonal pyramid geometry for the complex are discussed based on the ESR spectra.

  7. Randomised controlled trial of a digitally assisted low intensity intervention to promote personal recovery in persisting psychosis: SMART-Therapy study protocol.

    Science.gov (United States)

    Thomas, Neil; Farhall, John; Foley, Fiona; Rossell, Susan L; Castle, David; Ladd, Emma; Meyer, Denny; Mihalopoulos, Cathrine; Leitan, Nuwan; Nunan, Cassy; Frankish, Rosalie; Smark, Tara; Farnan, Sue; McLeod, Bronte; Sterling, Leon; Murray, Greg; Fossey, Ellie; Brophy, Lisa; Kyrios, Michael

    2016-09-07

    Psychosocial interventions have an important role in promoting recovery in people with persisting psychotic disorders such as schizophrenia. Readily available, digital technology provides a means of developing therapeutic resources for use together by practitioners and mental health service users. As part of the Self-Management and Recovery Technology (SMART) research program, we have developed an online resource providing materials on illness self-management and personal recovery based on the Connectedness-Hope-Identity-Meaning-Empowerment (CHIME) framework. Content is communicated using videos featuring persons with lived experience of psychosis discussing how they have navigated issues in their own recovery. This was developed to be suitable for use on a tablet computer during sessions with a mental health worker to promote discussion about recovery. This is a rater-blinded randomised controlled trial comparing a low intensity recovery intervention of eight one-to-one face-to-face sessions with a mental health worker using the SMART website alongside routine care, versus an eight-session comparison condition, befriending. The recruitment target is 148 participants with a schizophrenia-related disorder or mood disorder with a history of psychosis, recruited from mental health services in Victoria, Australia. Following baseline assessment, participants are randomised to intervention, and complete follow up assessments at 3, 6 and 9 months post-baseline. The primary outcome is personal recovery measured using the Process of Recovery Questionnaire (QPR). Secondary outcomes include positive and negative symptoms assessed with the Positive and Negative Syndrome Scale, subjective experiences of psychosis, emotional symptoms, quality of life and resource use. Mechanisms of change via effects on self-stigma and self-efficacy will be examined. This protocol describes a novel intervention which tests new therapeutic methods including in-session tablet computer use and

  8. Digital mammography; Mamografia digital

    Energy Technology Data Exchange (ETDEWEB)

    Chevalier, M.; Torres, R.

    2010-07-01

    Mammography represents one of the most demanding radiographic applications, simultaneously requiring excellent contrast sensitivity, high spatial resolution, and wide dynamic range. Film/screen is the most widely extended image receptor in mammography due to both its high spatial resolution and contrast. The film/screen limitations are related with its narrow latitude, structural noise and that is at the same time the medium for the image acquisition, storage and presentation. Several digital detector made with different technologies can overcome these difficulties. Here, these technologies as well as their main advantages and disadvantages are analyzed. Also it is discussed its impact on the mammography examinations, mainly on the breast screening programs. (Author).

  9. Digital Tectonics

    DEFF Research Database (Denmark)

    Christiansen, Karl; Borup, Ruben; Søndergaard, Asbjørn

    2014-01-01

    Digital Tectonics treats the architectonical possibilities in digital generation of form and production. The publication is the first volume of a series, in which aspects of the strategic focus areas of the Aarhus School of Architecture will be disseminated.......Digital Tectonics treats the architectonical possibilities in digital generation of form and production. The publication is the first volume of a series, in which aspects of the strategic focus areas of the Aarhus School of Architecture will be disseminated....

  10. Digital squares

    DEFF Research Database (Denmark)

    Forchhammer, Søren; Kim, Chul E

    1988-01-01

    Digital squares are defined and their geometric properties characterized. A linear time algorithm is presented that considers a convex digital region and determines whether or not it is a digital square. The algorithm also determines the range of the values of the parameter set of its preimages....... The analysis involves transforming the boundary of a digital region into parameter space of slope and y-intercept...

  11. Digital skrivedidaktik

    DEFF Research Database (Denmark)

    Digital skrivedidaktik består af to dele. Første del præsenterer teori om skrivekompetence og digital skrivning. Digital skrivning er karakteriseret ved at tekster skrives på computer og med digitale værktøjer, hvilket ændrer skrivningens traditionelle praksis, produkt og processer. Hvad er digital...... om elevens skriveproces) og Blogskrivning (der styrker eleverne i at bruge blogs i undervisningen)....

  12. Phenylethanoid Glycoside Profiles and Antioxidant Activities of Osmanthus fragrans Lour. Flowers by UPLC/PDA/MS and Simulated Digestion Model.

    Science.gov (United States)

    Jiang, Yirong; Mao, Shuqin; Huang, Weisu; Lu, Baiyi; Cai, Zengxuan; Zhou, Fei; Li, Maiquan; Lou, Tiantian; Zhao, Yajing

    2016-03-30

    Variations of phenylethanoid glycoside profiles and antioxidant activities in Osmanthus fragrans flowers through the digestive tract were evaluated by a simulated digestion model and UPLC/PDA/MS. Major phenylethanoid glycosides and phenolic acids, namely, salidroside, acteoside, isoacteoside, chlorogenic acid, and caffeic acid, were identified in four cultivars of O. fragrans flowers, and the concentration of acteoside was the highest, being up to 71.79 mg/g dry weight. After simulated digestion, total phenylethanoid glycoside contents and antioxidant activities were significantly decreased. Acteoside was identified as decomposing into caffeic acid, whereas salidroside was found to be stable during simulated digestion. According to Pearson's correlation analysis, acteoside contents showed good correlations with antioxidant activities during simulated digestion (R(2) = 0.994, P < 0.01). In conclusion, acteoside was the major contributor to the antioxidant activity of O. fragrans flowers, and salidroside was considered as the major antioxidant compound of O. fragrans flowers in vivo.

  13. Digital Citizenship

    Science.gov (United States)

    Isman, Aytekin; Canan Gungoren, Ozlem

    2014-01-01

    Era in which we live is known and referred as digital age.In this age technology is rapidly changed and developed. In light of these technological advances in 21st century, schools have the responsibility of training "digital citizen" as well as a good citizen. Digital citizens must have extensive skills, knowledge, Internet and …

  14. Determining the degradation efficiency and mechanisms of ethyl violet using HPLC-PDA-ESI-MS and GC-MS

    Directory of Open Access Journals (Sweden)

    Chung Wen-Hsin

    2012-06-01

    Full Text Available Abstract Background The discharge of wastewater that contains high concentrations of reactive dyes is a well-known problem associated with dyestuff activities. In recent years, semiconductor photocatalysis has become more and more attractive and important since it has a great potential to contribute to such environmental problems. One of the most important aspects of environmental photocatalysis is in the selection of semiconductor materials like ZnO and TiO2, which are close to being two of the ideal photocatalysts in several respects. For example, they are relatively inexpensive, and they provide photo-generated holes with high oxidizing power due to their wide band gap energy. In this work, nanostructural ZnO film on the Zn foil of the Alkaline-Manganese Dioxide-Zinc Cell was fabricated to degrade EV dye. The major innovation of this paper is to obtain the degradation mechanism of ethyl violet dyes resulting from the HPLC-PDA-ESI-MS analyses. Results The fabrication of ZnO nanostructures on zinc foils with a simple solution-based corrosion strategy and the synthesis, characterization, application, and implication of Zn would be reported in this study. Other objectives of this research are to identify the reaction intermediates and to understand the detailed degradation mechanism of EV dye, as model compound of triphenylmethane dye, with active Zn metal, by HPLC-ESI-MS and GC-MS. Conclusions ZnO nanostructure/Zn-foils had an excellent potential for future applications on the photocatalytic degradation of the organic dye in the environmental remediation. The intermediates of the degradation process were separated and characterized by the HPLC-PDA-ESI-MS and GC-MS, and twenty-six intermediates were characterized in this study. Based on the variation of the amount of intermediates, possible degradation pathways for the decolorization of dyes are also proposed and discussed.

  15. Digital subtraktion

    DEFF Research Database (Denmark)

    Mussmann, Bo Redder

    2004-01-01

    Digital subtraktion er en metode til at fjerne uønskede oplysninger i et røntgenbillede. Subtraktionsteknikken bruges primært i forbindelse med angiografi hvor man kun er interesseret i at se selve karret. Derfor er digital subtraktion i daglig tale synonymt med DSA eller DVI – hhv. Digital...... Subtraction Angiography eller Digital Vascular Imaging. Benævnelserne er to røntgenfirmaers navn for den samme teknik. Digital subtraktion kræver speciel software, samt at apparaturet kan eksponere i serier....

  16. Digital preservation

    CERN Document Server

    Deegan, Marilyn

    2013-01-01

    Digital preservation is an issue of huge importance to the library and information profession right now. With the widescale adoption of the internet and the rise of the world wide web, the world has been overwhelmed by digital information. Digital data is being produced on a massive scale by individuals and institutions: some of it is born, lives and dies only in digital form, and it is the potential death of this data, with its impact on the preservation of culture, that is the concern of this book. So how can information professionals try to remedy this? Digital preservation is a complex iss

  17. Digital Natives or Digital Tribes?

    Science.gov (United States)

    Watson, Ian Robert

    2013-01-01

    This research builds upon the discourse surrounding digital natives. A literature review into the digital native phenomena was undertaken and found that researchers are beginning to identify the digital native as not one cohesive group but of individuals influenced by other factors. Primary research by means of questionnaire survey of technologies…

  18. Preliminary comparison of the Essie and PubMed search engines for answering clinical questions using MD on Tap, a PDA-based program for accessing biomedical literature.

    Science.gov (United States)

    Sutton, Victoria R; Hauser, Susan E

    2005-01-01

    MD on Tap, a PDA application that searches and retrieves biomedical literature, is specifically designed for use by mobile healthcare professionals. With the goal of improving the usability of the application, a preliminary comparison was made of two search engines (PubMed and Essie) to determine which provided most efficient path to the desired clinically-relevant information.

  19. Changing Content Industry Structures: The Case of Digital Newspapers on ePaper Mobile Devices

    OpenAIRE

    L. Van Audenhove; S. Delaere; P. Ballon; M. Van Bossuyt

    2007-01-01

    The proposed paper analyses the changes in business models employed by the stakeholders in the newspaper value network, in the context of a new type of electronic reading device -the ePaper. This PDA-like device uses a new high-contrast, low-power screen technology (eInk), which holds the promise of a digital and mobile reading experience close to that of 'real' paper. The potential impact of massive digitally distributed reading content -newspapers, but also magazines, books, and all other m...

  20. A PDA based Point of Care E-Health Solution for Ambulatory Care

    Directory of Open Access Journals (Sweden)

    Daniel Walsh

    2005-11-01

    Full Text Available The adoption of PDAs and mobile communication is expected to provide a solution to the use of computer technology by healthcare workers at the point-of-care. The Australian National Health Information Strategy, Health Online, is providing national leadership for approaches to address the quality and availability of information to assist in the planning and delivery of care. One area for potential growth is the availability and capture of information at the point of care by healthcare providers. A key factor in the lack of adoption of systems, is that traditionally health care information systems have been designed for desktop computing whereas many healthcare workers are highly mobile. This paper discusses phase one of a larger, four-phase project which aims to develop information access applications at point-of-care for Ambulatory Care Services. The initial phase of the research (phase one involves workflow analysis, requirements specification and the development and testing of a system prototype to assess the feasibility of achieving increased efficiencies in workflow at the Ambulatory Care Service.

  1. Digital mammography

    International Nuclear Information System (INIS)

    Bick, Ulrich; Diekmann, Felix

    2010-01-01

    This state-of-the-art reference book provides in-depth coverage of all aspects of digital mammography, including detector technology, image processing, computer-aided diagnosis, soft-copy reading, digital workflow, and PACS. Specific advantages and disadvantages of digital mammography in comparison to screen-film mammography are thoroughly discussed. By including authors from both North America and Europe, the book is able to outline variations in the use, acceptance, and quality assurance of digital mammography between the different countries and screening programs. Advanced imaging techniques and future developments such as contrast mammography and digital breast tomosynthesis are also covered in detail. All of the chapters are written by internationally recognized experts and contain numerous high-quality illustrations. This book will be of great interest both to clinicians who already use or are transitioning to digital mammography and to basic scientists working in the field. (orig.)

  2. Digital Insights

    DEFF Research Database (Denmark)

    Knudsen, Gry Høngsmark

    , by incorporating media as both channel, frame, and apparatus for advertising response, the dissertation brings into attention that more aspects than the text-reader relationship influence ad response. Finally, the dissertation proposes the assemblage approach for exploring big data in consumer culture research...... and practices with digital media, when they meet and interpret advertising. Through studies of advertising response on YouTube and experiments with consumers’ response to digitally manipulated images, the dissertation shows how digital media practices facilitate polysemic and socially embedded advertising......This dissertation forwards the theory of digital consumer-response as a perspective to examine how digital media practices influence consumers’ response to advertising. Digital consumer-response is a development of advertising theory that encompasses how consumers employ their knowledge...

  3. Digital Signage

    OpenAIRE

    Fischer, Karl Peter

    2011-01-01

    Digital Signage for in-store advertising at gas stations/retail stores in Germany: A field study Digital Signage networks provide a novel means of advertising with the advantage of easily changeable and highly customizable animated content. Despite the potential and increasing use of these media empirical research is scarce. In a field study at 8 gas stations (with integrated convenience stores) we studied the effect of digital signage advertising on sales for different products and servi...

  4. Sports Digitalization

    DEFF Research Database (Denmark)

    Xiao, Xiao; Hedman, Jonas; Tan, Felix Ter Chian

    2017-01-01

    evolution, as digital technologies are increasingly entrenched in a wide range of sporting activities and for applications beyond mere performance enhancement. Despite such trends, research on sports digitalization in the IS discipline is surprisingly still nascent. This paper aims at establishing...... a discourse on sports digitalization within the discipline. Toward this, we first provide an understanding of the institutional characteristics of the sports industry, establishing its theoretical importance and relevance in our discipline; second, we reveal the latest trends of digitalization in the sports...

  5. Digital printing

    Science.gov (United States)

    Sobotka, Werner K.

    1997-02-01

    Digital printing is described as a tool to replace conventional printing machines completely. Still this goal was not reached until now with any of the digital printing technologies to be described in the paper. Productivity and costs are still the main parameters and are not really solved until now. Quality in digital printing is no problem anymore. Definition of digital printing is to transfer digital datas directly on the paper surface. This step can be carried out directly or with the use of an intermediate image carrier. Keywords in digital printing are: computer- to-press; erasable image carrier; image carrier with memory. Digital printing is also the logical development of the new digital area as it is pointed out in Nicholas Negropotes book 'Being Digital' and also the answer to networking and Internet technologies. Creating images text and color in one country and publishing the datas in another country or continent is the main advantage. Printing on demand another big advantage and last but not least personalization the last big advantage. Costs and being able to coop with this new world of prepress technology is the biggest disadvantage. Therefore the very optimistic growth rates for the next few years are really nonexistent. The development of complete new markets is too slow and the replacing of old markets is too small.

  6. Epimenides: Interoperability Reasoning for Digital Preservation

    NARCIS (Netherlands)

    Kargakis, Yannis; Tzitzikas, Yannis; van Horik, M.P.M.

    2014-01-01

    This paper presents Epimenides, a system that implements a novel interoperability dependency reasoning approach for assisting digital preservation activities. A distinctive feature is that it can model also converters and emulators, and the adopted modelling approach enables the automatic reasoning

  7. Photogrammetry, Digital mapping and Land Informations Systems

    DEFF Research Database (Denmark)

    Frederiksen, Poul

    1998-01-01

    Monitoring activities on photogrammetry, digital mapping and land information systems in State Land Service in Latvia in relation to the EU Phare Project Phase II, Technical Assistance to land Privatisation and registration in Latvia.......Monitoring activities on photogrammetry, digital mapping and land information systems in State Land Service in Latvia in relation to the EU Phare Project Phase II, Technical Assistance to land Privatisation and registration in Latvia....

  8. Facile synthesis of Fe3O4@PDA core-shell microspheres functionalized with various metal ions: A systematic comparison of commonly-used metal ions for IMAC enrichment.

    Science.gov (United States)

    Jiang, Jiebing; Sun, Xueni; Li, Yan; Deng, Chunhui; Duan, Gengli

    2018-02-01

    Metal ions differed greatly in affinity towards phosphopeptides, and thus it is essential to systematically compare the phosphopeptides enrichment ability of different metal ions usually used in the IMAC techniques. In this work, for the first time, eight metal ions, including Nb 5+ , Ti 4+ , Zr 4+ , Ga 3+ , Y 3+ , In 3+ , Ce 4+ , Fe 3+ , were immobilized on the polydopamine (PDA)-coated Fe 3 O 4 (denoted as Fe 3 O 4 @PDA-M n+ ), and systematically compared by the real biosamples, in addition to standard phosphopeptides. Fe 3 O 4 microspheres were synthesized via the solvothermal reaction, followed by self-polymerization of dopamine on the surface. Then through taking advantage of the hydroxyl and amino group of PDA, the eight metal ions were easily adhered to the surface of Fe 3 O 4 @PDA. After characterization, the resultant Fe 3 O 4 @PDA-M n+ microspheres were applied to phosphopeptides enrichment based on the binding affinity between metal ions and phosphopeptides. According to the results, different metal ions presented diverse phosphopeptides enrichment efficiency in terms of selectivity, sensitivity and the enrichment ability from real complex samples, and Fe 3 O 4 @PDA-Nb 5+ and Fe 3 O 4 @PDA-Ti 4+ showed obvious advantages of the phosphopeptides enrichment effect after the comparison. This systematic comparison may provide certain reference for the use and development of IMAC materials in the future. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Digital Audiobooks

    DEFF Research Database (Denmark)

    Have, Iben; Pedersen, Birgitte Stougaard

    Audiobooks are rapidly gaining popularity with widely accessible digital downloading and streaming services. The paper is framing how the digital audiobook expands and changes the target groups for book publications and how it as an everyday activity is creating new reading experiences, places...

  10. Digital TMI

    Science.gov (United States)

    Rios, Joseph

    2012-01-01

    Presenting the current status of the Digital TMI project to visiting members of the FAA Command Center. Digital TMI is an effort to store national-level traffic management initiatives in a standards-compliant manner. Work is funded by the FAA.

  11. Digital interactive learning of oral radiographic anatomy.

    Science.gov (United States)

    Vuchkova, J; Maybury, T; Farah, C S

    2012-02-01

    Studies reporting high number of diagnostic errors made from radiographs suggest the need to improve the learning of radiographic interpretation in the dental curriculum. Given studies that show student preference for computer-assisted or digital technologies, the purpose of this study was to develop an interactive digital tool and to determine whether it was more successful than a conventional radiology textbook in assisting dental students with the learning of radiographic anatomy. Eighty-eight dental students underwent a learning phase of radiographic anatomy using an interactive digital tool alongside a conventional radiology textbook. The success of the digital tool, when compared to the textbook, was assessed by quantitative means using a radiographic interpretation test and by qualitative means using a structured Likert scale survey, asking students to evaluate their own learning outcomes from the digital tool. Student evaluations of the digital tool showed that almost all participants (95%) indicated that the tool positively enhanced their learning of radiographic anatomy and interpretation. The success of the digital tool in assisting the learning of radiographic interpretation is discussed in the broader context of learning and teaching curricula, and preference (by students) for the use of this digital form when compared to the conventional literate form of the textbook. Whilst traditional textbooks are still valued in the dental curriculum, it is evident that the preference for computer-assisted learning of oral radiographic anatomy enhances the learning experience by enabling students to interact and better engage with the course material. © 2011 John Wiley & Sons A/S.

  12. Digitized mammograms

    International Nuclear Information System (INIS)

    Bruneton, J.N.; Balu-Maestro, C.; Rogopoulos, A.; Chauvel, C.; Geoffray, A.

    1988-01-01

    Two observers conducted a blind evaluation of 100 mammography files, including 47 malignant cases. Films were read both before and after image digitization at 50 μm and 100 μm with the FilmDRSII. Digitization permitted better analysis of the normal anatomic structures and moderately improved diagnostic sensitivity. Searches for microcalcifications before and after digitization at 100 μm and 50 μm showed better analysis of anatomic structures after digitization (especially for solitary microcalcifications). The diagnostic benefit, with discovery of clustered microcalcifications, was more limited (one case at 100 μm, nine cases at 50 μm). Recognition of microcalcifications was clearly improved in dense breasts, which can benefit from reinterpretation after digitization at 50 μm rather 100μm

  13. UPLC-PDA-Q/TOF-MS Profile of Polyphenolic Compounds of Liqueurs from Rose Petals (Rosa rugosa).

    Science.gov (United States)

    Cendrowski, Andrzej; Ścibisz, Iwona; Kieliszek, Marek; Kolniak-Ostek, Joanna; Mitek, Marta

    2017-10-27

    Polyphenolic compounds, as a secondary metabolite of plants, possess great nutritional and pharmacological potential. Herein, we applied the green analytical method to study the nutrient profile of Rosa rugosa petals and liqueurs manufactured from them. Using the fast and validated ultra performance liquid chromatography-photodiode detector-quadrupole/time of flight-mass spectrometry (UPLC-PDA-Q/TOF-MS) method, we confirm the presence of the following compounds: phenolic acids, flavonols, flavan-3-ols and hydrolisable tannins (gallotannins and ellagitannins). R. rugosa petals contains up to 2175.43 mg polyphenols per 100 g fresh weight, therein 1517.01 mg ellagitannins per 100 g fresh weight. Liqueurs, traditionally manufactured from said petals using a conventional extraction method (maceration), also contain polyphenols in significant amounts (from 72% to 96% corresponding to percentage of theoretical polyphenol content in the used petals), therein ellagitannins amount to 69.7% on average. We confirmed that traditional maceration, most common for the isolation of polyphenols, is still suitable for the food industry due to its using aqueous ethanol, a common bio-solvent, easily available in high purity and completely biodegradable. Therefore R. rugosa used as a food may be considered as an ellagitannin-rich plant of economic importance. Manufactured rose liqueurs were stable and kept all their properties during the whole period of aging.

  14. Comparison Study of the Response of Several Passive PDA Based Personal Dosimeter to Gamma and X-Ray Radiation

    International Nuclear Information System (INIS)

    Cohen, S.; Abraham, A.; Pelled, O.; Tubul, Y.; Kresner, E.; Ashkenazi, A.; Yaar, I.

    2014-01-01

    In the case of a radiological terror event or a nuclear accident, there is a need to perform a fast and reliable personal dosimetry measurements for first responders and other intervention forces. The dosimeters should be simple, instant and cumulative readout small and lightweight energy independent (iv) wide dose range (v) withstand intense environments cheap, and disposable. In the last decade, two simple dosimeters were presented for radiological emergencies self-indicating radiation alert dosimeters (SIRAD) and (ii) RADview by J.P Labs and M/s RADeCO, respectively. Both dosimeters contain radio-chromic films based on PDA (poly-di-acetylene) material that change the colors in their active window as a function of radiation dose. In the current study, the dose response of SIRAD and RADview personal dosimeters to 137Cs and M150 X-Ray radiation at the range of 0.01-11 Sv is presented. In addition, the environmental, fading effects and usage effects on the response of these dosimeters is evaluated

  15. Gas separation performance of carbon molecular sieve membranes based on 6FDA-mPDA/DABA (3:2) polyimide.

    Science.gov (United States)

    Qiu, Wulin; Zhang, Kuang; Li, Fuyue Stephanie; Zhang, Ke; Koros, William J

    2014-04-01

    6FDA-mPDA/DABA (3:2) polyimide was synthesized and characterized for uncross-linked, thermally crosslinked, and carbon molecular sieve (CMS) membranes. The membranes were characterized with thermogravimetric analysis, FTIR spectroscopy, wide-angle X-ray diffraction, and gas permeation tests. Variations in the d spacing, the formation of pore structures, and changes in the pore sizes of the CMS membranes were discussed in relation to pyrolysis protocols. The uncross-linked polymer membranes showed high CO2 /CH4 selectivity, whereas thermally crosslinked membranes exhibited significantly improved CO2 permeability and excellent CO2 plasticization resistance. The CMS membranes showed even higher CO2 permeability and CO2 /CH4 selectivity. An increase in the pyrolysis temperature resulted in CMS membranes with lower gas permeability but higher selectivity. The 550 °C pyrolyzed CMS membranes showed CO2 permeability as high as 14 750 Barrer with CO2 /CH4 selectivity of approximately 52. Even 800 °C pyrolyzed CMS membranes still showed high CO2 permeability of 2610 Barrer with high CO2 /CH4 selectivity of approximately 118. Both polymer membranes and the CMS membranes are very attractive in aggressive natural gas purification applications. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  16. Rapid identification and quantitative analysis of chemical constituents of Gentiana veitchiorum by UHPLC-PDA-QTOF-MS

    Directory of Open Access Journals (Sweden)

    Shan Li

    Full Text Available ABSTRACT Gentiana veitchiorum Hemsl., Gentianaceae, a traditional Tibetan medicine, was used for the treatment of liver jaundice with damp-heat pathogen, as well as for headache and chronic pharyngitis. A rapid ultra-performance liquid chromatography, photodiode array detector, quadrupole time-of-flight mass spectrometry method was developed for the fast and accurate identification and quantification of the chemical constituents of G. veitchiorum. In fact, eighteen compounds were detected and identified on the basis of their mass spectra, fragment characteristics and comparison with published data. Especially, the MS fragmentation pathways of iridoid glycosides and flavone C-glycosides were illustrated. Five compounds among them were quantified by UHPLC-PDA, including swertiamarin, gentiopicroside, sweroside, isoorientin, and isovitexin. The proposed method was then validated based on the analyses of linearity, accuracy, precision, and recovery. The overall recoveries for the five analytes ranged from 96.54% to 100.81%, with RSD from 1.05% to 1.82%. In addition, ten batches of G. veitchiorum from different areas were also analyzed. The developed method was rapid and reliable for both identification and quantification of the chemical constituents of G. veitchiorum, especially for simultaneous qualitative and quantitative analysis of iridoid glycosides and flavone C-glycosides.

  17. Determination of anthocyanins from camu-camu (Myrciaria dubia) by HPLC-PDA, HPLC-MS, and NMR.

    Science.gov (United States)

    Zanatta, Cinthia Fernanda; Cuevas, Elyana; Bobbio, Florinda O; Winterhalter, Peter; Mercadante, Adriana Z

    2005-11-30

    Camu-camu [Myrciaria dubia (HBK) McVaugh] is a small fruit native to the Amazonian rain forest. Its anthocyanin profile has now been investigated for the first time. Fruits from two different regions of the São Paulo state, Brazil, were analyzed. The major anthocyanins were isolated by high-speed countercurrent chromatography. HPLC-PDA, HPLC-MS/MS, and 1H NMR were used to confirm the identity of the main anthocyanins of camu-camu. Cyanidin-3-glucoside was identified as the major pigment in the fruits from both regions, representing 89.5% in the fruits produced in Iguape and 88.0% in those from Mirandópolis, followed by the delphinidin-3-glucoside, ranging between 4.2 and 5.1%, respectively. Higher total anthocyanin contents were detected in the fruits from Iguape (54.0 +/- 25.9 mg/100 g) compared to those from Mirandópolis (30.3 +/- 6.8 mg/100 g), most likely because of the lower temperatures in the Iguape region.

  18. Soldier Flexible Personal Digital Assistant Program

    National Research Council Canada - National Science Library

    Price, Mark; Woytowich, Jason; Carlson, Marc

    2008-01-01

    ... and mechanical enclosures that better conform to body-worn computing requirements and also have relatively low power requirements. The reduction of the size and weight of batteries needed will lengthen mission profiles and also improve body-worn requirements.

  19. Developer Network : Open Source Personal Digital Assistant ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Each project used a different software, however, and this proved costly in terms of ... development and evaluation of PDACT, a Palm TM pilot interviewing system ... IWRA/IDRC webinar on climate change and adaptive water management.

  20. Developer Network : Open Source Personal Digital Assistant ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Articles de revue. Handheld computers for survey and trial data collection in resource-poor settings : development and evaluation of PDACT, a Palm TM pilot interviewing system ... L'Initiative des conseils subventionnaires de la recherche scientifique en Afrique subsaharienne remporte le prix de la diplomatie scientifique.

  1. Digital Ethics/Going Digital.

    Science.gov (United States)

    Wilson, Bradley

    1996-01-01

    Finds that the recent National Press Photographers Association code of ethics can serve as a model for any photography staff. Discusses how digital imaging is becoming commonplace in classrooms, due to decreasing costs and easier software. Explains digital terminology. Concludes that time saved in the darkroom and at the printer is now spent on…

  2. Lithium Suppresses Hedgehog Signaling via Promoting ITCH E3 Ligase Activity and Gli1–SUFU Interaction in PDA Cells

    Directory of Open Access Journals (Sweden)

    Xinshuo Wang

    2017-11-01

    Full Text Available Dysregulation of Hedgehog (Hh signaling pathway is one of the hallmarks of pancreatic ductal adenocarcinoma (PDA. Lithium, a clinical mood stabilizer for the treatment of mental disorders, is known to suppress tumorigenic potential of PDA cells by targeting the Hh/Gli signaling pathway. In this study, we investigated the molecular mechanism of lithium induced down-regulation of Hh/Gli1. Our data show that lithium promotes the poly-ubiquitination and proteasome-mediated degradation of Gli1 through activating E3 ligase ITCH. Additionally, lithium enhances interaction between Gli1 and SUFU via suppressing GSK3β, which phosphorylates SUFU and destabilizes the SUFU-Gli1 inhibitory complex. Our studies illustrate a novel mechanism by which lithium suppresses Hh signaling via simultaneously promoting ITCH-dependent Gli1 ubiquitination/degradation and SUFU-mediated Gli1 inhibition.

  3. Digital radiography

    International Nuclear Information System (INIS)

    Coulomb, M.; Dal Soglio, S.; Pittet-Barbier, L.; Ranchoup, Y.; Thony, F.; Ferretti, G.; Robert, F.

    1992-01-01

    Digital projection radiography may replace conventional radiography some day, provided it can meet several requirements: equal or better diagnostic effectiveness of the screen-film systems; reasonable image cost; real improvement in the productivity of the Departments of Imaging. All digital radiographic systems include an X-ray source, an image acquisition and formatting sub-system, a display and manipulation sub-system, and archiving subsystem and a laser editing system, preferably shared by other sources of digital images. Three digitization processes are available: digitization of the radiographic film, digital fluorography and phospholuminescent detectors with memory. The advantages of digital fluoroscopy are appealing: real-time image acquisition, suppression of cassettes; but its disadvantages are far from negligible: it cannot be applied to bedside radiography, the field of examination is limited, and the wide-field spatial resolution is poor. Phospholuminescent detectors with memory have great advantages: they can be used for bedside radiographs and on all the common radiographic systems; spatial resolution is satisfactory; its current disadvantages are considerable. These two systems, have common properties making up the entire philosophy of digital radiology and specific features that must guide our choice according to the application. Digital fluorography is best applied in pediatric radiology. However, evaluation works have showed that it was applicable with sufficient quality to many indications of general radiology in which a fluoroscopic control and fast acquisition of the images are essential; the time gained on the examination may be considerable, as well as the savings on film. Detectors with memory are required for bedside radiographs, in osteoarticular and thoracic radiology, in all cases of traumatic emergency and in the resuscitation and intensive care departments

  4. Becoming digital

    DEFF Research Database (Denmark)

    Pors, Anja Svejgaard

    2015-01-01

    . An ethnographic account of how digital reforms are implemented in practice shows how street-level bureaucrat’s classic tasks such as specialized casework are being reconfigured into educational tasks that promote the idea of “becoming digital”. In the paper, the author argues that the work of “becoming digital....... Originality/value: The study contributes to ethnographic research in public administration by combining two separate subfields, e-government and street-level bureaucracy, to discern recent transformations in public service delivery. In the digital era, tasks, control and equality are distributed in ways...

  5. Digital Humanities

    DEFF Research Database (Denmark)

    Brügger, Niels

    2016-01-01

    , and preserving material to study, as an object of study in its own right, as an analytical tool, or for collaborating, and for disseminating results. The term "digital humanities" was coined around 2001, and gained currency within academia in the following years. However, computers had been used within......Digital humanities is an umbrella term for theories, methodologies, and practices related to humanities scholarship that use the digital computer as an integrated and essential part of its research and teaching activities. The computer can be used for establishing, finding, collecting...

  6. Digital Snaps

    DEFF Research Database (Denmark)

    Sandbye, Mette; Larsen, Jonas

    . Distance as the New Punctum / Mikko Villi -- pt. II. FAMILY ALBUMS IN TRANSITION -- ch. 4. How Digital Technologies Do Family Snaps, Only Better / Gillian Rose -- ch. 5. Friendship Photography: Memory, Mobility and Social Networking / Joanne Garde-Hansen -- ch. 6. Play, Process and Materiality in Japanese...... -- ch. 9. Retouch Yourself: The Pleasures and Politics of Digital Cosmetic Surgery / Tanya Sheehan -- ch. 10. Virtual Selves: Art and Digital Autobiography / Louise Wolthers -- ch. 11. Mobile-Media Photography: New Modes of Engagement / Michael Shanks and Connie Svabo....

  7. Digital electronics

    CERN Document Server

    Morris, John

    2013-01-01

    An essential companion to John C Morris's 'Analogue Electronics', this clear and accessible text is designed for electronics students, teachers and enthusiasts who already have a basic understanding of electronics, and who wish to develop their knowledge of digital techniques and applications. Employing a discovery-based approach, the author covers fundamental theory before going on to develop an appreciation of logic networks, integrated circuit applications and analogue-digital conversion. A section on digital fault finding and useful ic data sheets completes th

  8. Digital Leadership

    DEFF Research Database (Denmark)

    Zupancic, Tadeja; Verbeke, Johan; Achten, Henri

    2016-01-01

    Leadership is an important quality in organisations. Leadership is needed to introduce change and innovation. In our opinion, in architectural and design practices, the role of leadership has not yet been sufficiently studied, especially when it comes to the role of digital tools and media....... With this paper we intend to initiate a discussion in the eCAADe community to reflect and develop ideas in order to develop digital leadership skills amongst the membership. This paper introduces some important aspects, which may be valuable to look into when developing digital leadership skills....

  9. Digital radiography

    International Nuclear Information System (INIS)

    Zani, M.L.

    2002-01-01

    X-ray radiography is a very common technique used to check the homogeneity of a material or the inside of a mechanical part. Generally the radiation that goes through the material to check, produced an image on a sensitized film. This method requires time because the film needs to be developed, digital radiography has no longer this inconvenient. In digital radiography the film is replaced by digital data and can be processed as any computer file. This new technique is promising but its main inconvenient is that today its resolution is not so good as that of film radiography. (A.C.)

  10. Digital radiography

    International Nuclear Information System (INIS)

    Kusano, Shoichi

    1993-01-01

    Firstly, from an historic point of view, fundamental concepts on digital imaging were reviewed to provide a foundation for discussion of digital radiography. Secondly, this review summarized the results of ongoing research in computed radiography that replaces the conventional film-screen system with a photo-stimulable phosphor plate; and thirdly, image quality, radiation protection, and image processing techniques were discussed with emphasis on picture archiving and communication system environment as our final goal. Finally, future expansion of digital radiography was described based on the present utilization of computed tomography at the National Defense Medical College Hospital. (author) 60 refs

  11. Digital stethoscope: technology update

    Science.gov (United States)

    Swarup, Supreeya; Makaryus, Amgad N

    2018-01-01

    Cardiovascular disease (CVD) is recognized as the leading cause of mortality throughout the world. About one-third of global mortality is attributable to CVD. In addition to clinical presentation, specific clinical exam findings can assist in treating and preventing CVD. CVD may initially manifest as pulmonary pathology, and thus, accurate cardiopulmonary auscultation is paramount to establishing accurate diagnosis. One of the most powerful tools available to physicians is the stethoscope. The stethoscope first emerged in the year 1818, invented by a French physician, René Laennec. Since then, the initial modest monaural wooden tube has evolved into a sophisticated digital device. This paper provides an analysis of the evolution of the stethoscope as well as highlights the advancement made by the modern digital stethoscope including the application of this tool in advancing care for patients suffering from CVD. PMID:29379321

  12. Digital fabrication

    CERN Document Server

    2012-01-01

    The Winter 2012 (vol. 14 no. 3) issue of the Nexus Network Journal features seven original papers dedicated to the theme “Digital Fabrication”. Digital fabrication is changing architecture in fundamental ways in every phase, from concept to artifact. Projects growing out of research in digital fabrication are dependent on software that is entirely surface-oriented in its underlying mathematics. Decisions made during design, prototyping, fabrication and assembly rely on codes, scripts, parameters, operating systems and software, creating the need for teams with multidisciplinary expertise and different skills, from IT to architecture, design, material engineering, and mathematics, among others The papers grew out of a Lisbon symposium hosted by the ISCTE-Instituto Universitario de Lisboa entitled “Digital Fabrication – A State of the Art”. The issue is completed with four other research papers which address different mathematical instruments applied to architecture, including geometric tracing system...

  13. Digital Relationships

    DEFF Research Database (Denmark)

    Ledborg Hansen, Richard

    -­rich information and highly interesting communication are sky-­high and rising. With a continuous increase in digitized communication follows a decrease in face-­to-­face encounters and our ability to engage in inter-­personal relationships are suffering for it (Davis, 2013). The behavior described in this paper......-­‐Jones, 2011) for increases in effectiveness and efficiency we indiscriminately embrace digital communication and digitized information dissemination with enthusiasm – at the risk of ignoring the potentially dark side of technology. However, technology also holds a promise for better understanding precisely...... for the same reasons – that the growing amount of digitized communication “out there” represents data waiting to be sifted, analyzed and decoded. In this paper “Facebook behavior” refers to a particular behavior characterized by presenting your self and representations of selected self in the hope of getting...

  14. Digital Discretion

    DEFF Research Database (Denmark)

    Busch, Peter Andre; Zinner Henriksen, Helle

    2018-01-01

    discretion is suggested to reduce this footprint by influencing or replacing their discretionary practices using ICT. What is less researched is whether digital discretion can cause changes in public policy outcomes, and under what conditions such changes can occur. Using the concept of public service values......This study reviews 44 peer-reviewed articles on digital discretion published in the period from 1998 to January 2017. Street-level bureaucrats have traditionally had a wide ability to exercise discretion stirring debate since they can add their personal footprint on public policies. Digital......, we suggest that digital discretion can strengthen ethical and democratic values but weaken professional and relational values. Furthermore, we conclude that contextual factors such as considerations made by policy makers on the macro-level and the degree of professionalization of street...

  15. Implementation digital technologies in nuclear utilities

    International Nuclear Information System (INIS)

    Wiegand, C.; Maselli, A.J.

    2012-01-01

    The introduction of digital technologies into the nuclear industry has assisted in many ways and made many of the Life Extensions and Uprates a possibility. But with this introduction of digital technologies comes some potentially challenging issues which need to be addressed for ultimate project success. This presentation discusses what a nuclear utility should consider and establish when implementing digital technologies in their plant. Digital technologies have been employed in many safety critical industries such as Aerospace, Pharmaceutical, Oil and Gas, and Chemical. However, nuclear industry implementation of digital technologies has been slow and in many ways tenuous. There are even documented operating experience events in which plant trips/SCRAMs occurred during a digital system implementation. This presentation aims to prevent those issues drawing upon the lessons learned over the past 5 years. Considerations include general challenges to overcome when implementing Digital Technologies, how to justify and execute projects, evaluation of resource knowledge, and the new challenges of Cyber Security. (author)

  16. Implementation digital technologies in nuclear utilities

    Energy Technology Data Exchange (ETDEWEB)

    Wiegand, C.; Maselli, A.J., E-mail: Tony.Maselli@Invensys.com [Invensys Operations Management, London (United Kingdom)

    2012-07-01

    The introduction of digital technologies into the nuclear industry has assisted in many ways and made many of the Life Extensions and Uprates a possibility. But with this introduction of digital technologies comes some potentially challenging issues which need to be addressed for ultimate project success. This presentation discusses what a nuclear utility should consider and establish when implementing digital technologies in their plant. Digital technologies have been employed in many safety critical industries such as Aerospace, Pharmaceutical, Oil and Gas, and Chemical. However, nuclear industry implementation of digital technologies has been slow and in many ways tenuous. There are even documented operating experience events in which plant trips/SCRAMs occurred during a digital system implementation. This presentation aims to prevent those issues drawing upon the lessons learned over the past 5 years. Considerations include general challenges to overcome when implementing Digital Technologies, how to justify and execute projects, evaluation of resource knowledge, and the new challenges of Cyber Security. (author)

  17. Gas Separation Performance of Carbon Molecular Sieve Membranes Based on 6FDA-mPDA/DABA (3:2) Polyimide

    KAUST Repository

    Qiu, Wulin

    2014-02-23

    6FDA-mPDA/DABA (3:2) polyimide was synthesized and characterized for uncross-linked, thermally crosslinked, and carbon molecular sieve (CMS) membranes. The membranes were characterized with thermogravimetric analysis, FTIR spectroscopy, wide-angle X-ray diffraction, and gas permeation tests. Variations in the d spacing, the formation of pore structures, and changes in the pore sizes of the CMS membranes were discussed in relation to pyrolysis protocols. The uncross-linked polymer membranes showed high CO 2/CH4 selectivity, whereas thermally crosslinked membranes exhibited significantly improved CO2 permeability and excellent CO2 plasticization resistance. The CMS membranes showed even higher CO2 permeability and CO2/CH4 selectivity. An increase in the pyrolysis temperature resulted in CMS membranes with lower gas permeability but higher selectivity. The 550 °C pyrolyzed CMS membranes showed CO2 permeability as high as 14 750 Barrer with CO 2/CH4 selectivity of approximately 52. Even 800 °C pyrolyzed CMS membranes still showed high CO2 permeability of 2610 Barrer with high CO2/CH4 selectivity of approximately 118. Both polymer membranes and the CMS membranes are very attractive in aggressive natural gas purification applications. Permeating through: Polyimide-based uncross-linked, thermally crosslinked, and carbon molecular sieve (CMS) membranes are prepared. Variations in the d spacing, the formation of pore structures, and changes in the pore sizes of the CMS membranes are discussed in relation to pyrolysis protocols. Both the polymer and CMS membranes are very attractive in aggressive natural gas purification applications. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. UPLC-PDA-ESI-qTOF-MS profiling and potent anti-HSV-II activity of Eucalyptus sideroxylon leaves.

    Science.gov (United States)

    Okba, Mona M; El Gedaily, Rania A; Ashour, Rehab M

    2017-11-15

    Eucalyptus is one of the most important and highly exploited genus in family Myrtaceae. An UPLC/PDA/ESI-qTOF-MS method was adopted to identify Eucalyptus sideroxylon Cunn. ex Woolls leaves phytoconstituents. Cytotoxicity of E. sideroxylon leaves phloroglucinol-rich extract (PGRE) on VERO cells was determined. The antiviral effect of PGRE against hepatitis A (HAV), herpes simplex type 1 (HSV-I), herpes simplex type 2 (HSV-II), coxsackie (CoxB4), and adenoviruses was in vitro evaluated using MTT assay (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide). UPLC-MS analysis allowed the identification of 70 metabolites including: 26 triterpenes, 13 phloroglucinols, 8 fatty acids, 5 flavonoids, 5 oleuropeic acid glucosides, 3 gallic acid derivatives, and 10 miscellaneous. Twenty four metabolites identified in the leaves of E. sideroxylon and four in the genus Eucalyptus are reported herein for the first time. PGRE was found to be non-cytotoxic; the concentration that reduced the cell viability by 50% (CC 50 ) was 0.808mg/mL. Maximum non-toxic concentration (MNTC) of PGRE on Vero cells was 0.312mg/mL. The best antiviral activity was observed against HSV-II. Its mechanism was through decreasing the viral replication (IC 50 189.36μg/mL, 87.65% inhibition) and attachment on Vero cells (IC 50 199.34μg/mL, 83.13% inhibition) rather than virucidal effect (IC 50 293.1μg/mL, 50.68% inhibition). This study provides a complete map for E. sideroxylon leaves composition. It also suggests the plant as a source of new antiviral agents. Copyright © 2017 Elsevier B.V. All rights reserved.

  19. Pancreatic Ductal Adenocarcinoma (PDA) mice lacking Mucin 1 have a profound defect in tumor growth and metastasis

    Science.gov (United States)

    Besmer, Dahlia M.; Curry, Jennifer M.; Roy, Lopamudra D.; Tinder, Teresa L.; Sahraei, Mahnaz; Schettini, Jorge; Hwang, Sun-Il; Lee, Yong Y.; Gendler, Sandra J.; Mukherjee, Pinku

    2011-01-01

    MUC1 is over expressed and aberrantly glycosolated in >60% of pancreatic ductal adenocarcinomas. The functional role of MUC1 in pancreatic cancer has yet to be fully elucidated due to a dearth of appropriate models. In the present study, we have generated mouse models that spontaneously develop pancreatic ductal adenocarcinoma (KC), which are either Muc1-null (KCKO) or express human MUC1 (KCM). We show that KCKO mice have significantly slower tumor progression and rates of secondary metastasis, compared to both KC and KCM. Cell lines derived from KCKO tumors have significantly lower tumorigenic capacity compared to cells from KCM tumors. Therefore, mice with KCKO tumors had a significant survival benefit compared to mice with KCM tumors. In vitro, KCKO cells have reduced proliferation and invasion and failed to respond to epidermal growth factor (EGF), platelet-derived growth factor (PDGF), or matrix metalloproteinase-9 (MMP9). Further, significantly fewer KCKO cells entered the G2M phase of the cell cycle compared to the KCM cells. Proteomics and western blotting analysis revealed a complete loss of cdc-25c expression, phosphorylation of MAPK, as well as a significant decrease in Nestin and Tubulin α-2 chain expression in KCKO cells. Treatment with a MEK1/2 inhibitor, U0126, abrogated the enhanced proliferation of the KCM cells but had minimal effect on KCKO cells, suggesting that MUC1 is necessary for MAPK activity and oncogenic signaling. This is the first study to utilize a Muc1-null PDA mouse in order to fully elucidate the oncogenic role of MUC1, both in vivo and in vitro. PMID:21558393

  20. Digital Collections, Digital Libraries & the Digitization of Cultural Heritage Information.

    Science.gov (United States)

    Lynch, Clifford

    2002-01-01

    Discusses digital collections and digital libraries. Topics include broadband availability; digital rights protection; content, both non-profit and commercial; digitization of cultural content; sustainability; metadata harvesting protocol; infrastructure; authorship; linking multiple resources; data mining; digitization of reference works;…

  1. Assistive Technology

    Science.gov (United States)

    ... Page Resize Text Printer Friendly Online Chat Assistive Technology Assistive technology (AT) is any service or tool that helps ... be difficult or impossible. For older adults, such technology may be a walker to improve mobility or ...

  2. digital natives and digital immigrants

    OpenAIRE

    Cardina, Bruno; Francisco, Jerónimo; Reis, Pedro; trad. Silva, Fátima

    2011-01-01

    This article focuses on the generational gaps in school learning. Initially, we have tried to provide the framework in relation to the term digital native in order to understand the key aspects of the generation born after the advent and the global use of the Internet. They were found to be “multitasking” people, linked to technology and connectivity, as opposed to digital immigrants, born in an earlier period and seeking to adapt to the technological world. We also present some r...

  3. Assisted Living

    Science.gov (United States)

    ... it, too. Back to top What is the Cost for Assisted Living? Although assisted living costs less than nursing home ... Primarily, older persons or their families pay the cost of assisted living. Some health and long-term care insurance policies ...

  4. From Paper to PDA

    DEFF Research Database (Denmark)

    Kanstrup, Anne Marie; Stage, Jan

    2009-01-01

    Mobile devices with small screens and minimal facilities for interaction are increasingly being used in complex human activities for accessing and processing information, while the user is moving. This paper presents a case study of the design and evaluation of a mobile system, which involved...

  5. Digital evidence

    Directory of Open Access Journals (Sweden)

    Lukić Tatjana

    2012-01-01

    Full Text Available Although computer makes human activities faster and easier, innovating and creating new forms of work and other kinds of activities, it also influenced the criminal activity. The development of information technology directly affects the development of computer forensics without which, it can not even imagine the discovering and proving the computer offences and apprehending the perpetrator. Information technology and computer forensic allows us to detect and prove the crimes committed by computer and capture the perpetrators. Computer forensics is a type of forensics which can be defined as a process of collecting, preserving, analyzing and presenting digital evidence in court proceedings. Bearing in mind, that combat against crime, in which computers appear as an asset or object of the offense, requires knowledge of digital evidence as well as specific rules and procedures, the author in this article specifically addresses the issues of digital evidence, forensic (computer investigation, specific rules and procedures for detecting, fixing and collecting digital evidence and use of this type of evidence in criminal proceedings. The author also delas with international standards regarding digital evidence and cyber-space investigation.

  6. Digital watermark

    Directory of Open Access Journals (Sweden)

    Jasna Maver

    2000-01-01

    Full Text Available The huge amount of multimedia contents available on the World-Wide-Web is beginning to raise the question of their protection. Digital watermarking is a technique which can serve various purposes, including intellectual property protection, authentication and integrity verification, as well as visible or invisible content labelling of multimedia content. Due to the diversity of digital watermarking applicability, there are many different techniques, which can be categorised according to different criteria. A digital watermark can be categorised as visible or invisible and as robust or fragile. In contrast to the visible watermark where a visible pattern or image is embedded into the original image, the invisible watermark does not change the visual appearance of the image. The existence of such a watermark can be determined only through a watermark ex¬traction or detection algorithm. The robust watermark is used for copyright protection, while the fragile watermark is designed for authentication and integrity verification of multimedia content. A watermark must be detectable or extractable to be useful. In some watermarking schemes, a watermark can be extracted in its exact form, in other cases, we can detect only whether a specific given watermarking signal is present in an image. Digital libraries, through which cultural institutions will make multimedia contents available, should support a wide range of service models for intellectual property protection, where digital watermarking may play an important role.

  7. Current status and progress of digital orthopaedics in China

    Directory of Open Access Journals (Sweden)

    Guo-Xian Pei

    2014-07-01

    Full Text Available Based on the development of digital medicine and digital anatomy, the concept of “digital orthopaedics” was raised by Pei Guo-Xian in China in 2006. The most striking feature of digital orthopaedics is the combination of basic and clinical orthopaedic knowledge with digital technology. In this review, we summarised the development of digital orthopaedics in China in recent years with respect to: the foundation of the Chinese Association of Digital Orthopedics, virtual human project (VHP, three-dimensional (3D reconstruction, finite element simulation, navigation in orthopaedic operations, and robot-assisted orthopaedic operations. In addition, we briefly reviewed digital orthopaedics in world leading institutes. We also looked into the future of digital orthopaedics in China and proposed the major challenges in digital technology and application in orthopaedics.

  8. Digital Creativity

    DEFF Research Database (Denmark)

    Petersson Brooks, Eva; Brooks, Anthony Lewis

    2014-01-01

    This paper reports on a study exploring the outcomes from children’s play with technology in early childhood learning practices. The paper addresses questions related to how digital technology can foster creativity in early childhood learning environments. It consists of an analysis of children......’s interaction with the KidSmart furniture focusing on digital creativity potentials and play values suggested by the technology. The study applied a qualitative approach and included125 children (aged three to five), 10 pedagogues, and two librarians. The results suggests that educators should sensitively...... consider intervening when children are interacting with technology, and rather put emphasize into the integration of the technology into the environment and to the curriculum in order to shape playful structures for children’s digital creativity....

  9. Digital radiography

    International Nuclear Information System (INIS)

    Rath, M.; Lissner, J.; Rienmueller, R.; Haendle, J.; Siemens A.G., Erlangen

    1984-01-01

    Using a prototype of an electronic, universal examination unit equipped with a special X-ray TV installation, spotfilm exposures and digital angiographies with high spatial resolution and wide-range contrast could be made in the clinic for the first time. With transvenous contrast medium injection, the clinical results of digital angiography show excellent image quality in the region of the carotids and renal arteries as well as the arteries of the extremities. The electronic series exposures have an image quality almost comparable to the quality obtained with cutfilm changers in conventional angiography. There are certain limitations due to the input field of 25 cm X-ray image intensified used. In respect of the digital angiography imaging technique, the electronic universal unit is fully suitable for clinical application. (orig.) [de

  10. Digital photogrammetry

    CERN Document Server

    Egels, Yves

    2003-01-01

    Photogrammetry is the use of photography for surveying primarily and is used for the production of maps from aerial photographs. Along with remote sensing, it represents the primary means of generating data for Geographic Information Systems (GIS). As technology develops, it is becoming easier to gain access to it. The cost of digital photogrammetric workstations are falling quickly and these new tools are therefore becoming accessible to more and more users. Digital Photogrammetry is particularly useful as a text for graduate students in geomantic and is also suitable for people with a good basic scientific knowledge who need to understand photogrammetry, and who wish to use the book as a reference.

  11. Digital Marketing

    OpenAIRE

    Jerry Wind; Vijay Mahajan

    2002-01-01

    The digital revolution has shaken marketing to its core with consumers being offered greater price transparency and often even the chance to dictate the price. What does pricing mean in a world in which customers propose their own prices (as at priceline.com) or buyers and sellers haggle independently in auctions (as at e-Bay)? The most significant changes in the digital marketing show the emergence of 'cyber consumers', the cyber business-to-business world and the changing reality of an incr...

  12. Digital "X"

    DEFF Research Database (Denmark)

    Baiyere, Abayomi; Grover, Varun; Gupta, Alok

    2017-01-01

    Interest in using digital before existing research concepts seem to be on the rise in the IS field. This panel is positioned to explore what value lies in labelling our research as digital “x” as opposed to the well established IT “x” (where “x” can be strategy, infrastructure, innovation, artifa...... between this stream of research and existing research. Central among the expected output of the panel is the advancement of suggestions for future research and the critical pitfalls to avoid in doing so....

  13. Digital Radiography

    Science.gov (United States)

    1986-01-01

    System One, a digital radiography system, incorporates a reusable image medium (RIM) which retains an image. No film is needed; the RIM is read with a laser scanner, and the information is used to produce a digital image on an image processor. The image is stored on an optical disc. System allows the radiologist to "dial away" unwanted images to compare views on three screens. It is compatible with existing equipment and cost efficient. It was commercialized by a Stanford researcher from energy selective technology developed under a NASA grant.

  14. Digital filters

    CERN Document Server

    Hamming, Richard W

    1997-01-01

    Digital signals occur in an increasing number of applications: in telephone communications; in radio, television, and stereo sound systems; and in spacecraft transmissions, to name just a few. This introductory text examines digital filtering, the processes of smoothing, predicting, differentiating, integrating, and separating signals, as well as the removal of noise from a signal. The processes bear particular relevance to computer applications, one of the focuses of this book.Readers will find Hamming's analysis accessible and engaging, in recognition of the fact that many people with the s

  15. Digital voltmeter

    International Nuclear Information System (INIS)

    Yohannes Kamadi; Soekarno.

    1976-01-01

    The electrical voltage measuring equipment with digital display has been made. This equipment uses four digits display with single polarity measurement and integrating system. Pulses from the oscillator will be counted and converted to the staircase voltages, and compared to the voltage measured. When the balance is already achieved, the pulse will appear at the comparator circuit. This pulse will be used to trigger univibrator circuit. The univibrator output is used as signal for stopping the counting, and when reading time T already stops, the counting system will be reset. (authors)

  16. Digital communication

    CERN Document Server

    Das, Apurba

    2010-01-01

    ""Digital Communications"" presents the theory and application of the philosophy of Digital Communication systems in a unique but lucid form. This book inserts equal importance to the theory and application aspect of the subject whereby the authors selected a wide class of problems. The Salient features of the book are: the foundation of Fourier series, Transform and wavelets are introduces in a unique way but in lucid language; the application area is rich and resemblance to the present trend of research, as we are attached with those areas professionally; a CD is included which contains code

  17. Digital literacies

    CERN Document Server

    Hockly, Nicky; Pegrum, Mark

    2014-01-01

    Dramatic shifts in our communication landscape have made it crucial for language teaching to go beyond print literacy and encompass the digital literacies which are increasingly central to learners' personal, social, educational and professional lives. By situating these digital literacies within a clear theoretical framework, this book provides educators and students alike with not just the background for a deeper understanding of these key 21st-century skills, but also the rationale for integrating these skills into classroom practice. This is the first methodology book to address not jus

  18. The impact of digital imaging in the field of cytopathology.

    Science.gov (United States)

    Pantanowitz, Liron; Hornish, Maryanne; Goulart, Robert A

    2009-03-06

    With the introduction of digital imaging, pathology is undergoing a digital transformation. In the field of cytology, digital images are being used for telecytology, automated screening of Pap test slides, training and education (e.g. online digital atlases), and proficiency testing. To date, there has been no systematic review on the impact of digital imaging on the practice of cytopathology. This article critically addresses the emerging role of computer-assisted screening and the application of digital imaging to the field of cytology, including telecytology, virtual microscopy, and the impact of online cytology resources. The role of novel diagnostic techniques like image cytometry is also reviewed.

  19. Digital delicacies

    OpenAIRE

    Holley, Rose

    2001-01-01

    This presentation outlines the purpose and work of the newly appointed Digital Projects Librarian at the University of Auckland. It gives a brief overview of what digitisation is, the benefits, the stages of a digitisation project and also samples of interesting international digitisation projects and new University of Auckland Library Digitisation projects.

  20. Digital Forensics

    Science.gov (United States)

    Harron, Jason; Langdon, John; Gonzalez, Jennifer; Cater, Scott

    2017-01-01

    The term forensic science may evoke thoughts of blood-spatter analysis, DNA testing, and identifying molds, spores, and larvae. A growing part of this field, however, is that of digital forensics, involving techniques with clear connections to math and physics. This article describes a five-part project involving smartphones and the investigation…

  1. Digital Disruption

    DEFF Research Database (Denmark)

    Rosenstand, Claus Andreas Foss

    det digitale domæne ud over det niveau, der kendetegner den nuværende debat, så præsenteres der ny viden om digital disruption. Som noget nyt udlægges Clayton Christens teori om disruptiv innovation med et særligt fokus på små organisationers mulighed for eksponentiel vækst. Specielt udfoldes...... forholdet mellem disruption og den stadig accelererende digitale udvikling i konturerne til ny teoridannelse om digital disruption. Bogens undertitel ”faretruende og fascinerende forandringer” peger på, at der er behov for en nuanceret debat om digital disruption i modsætning til den tone, der er slået an i...... videre kalder et ”disruption-råd”. Faktisk er rådet skrevet ind i 2016 regeringsgrundlaget for VLK-regeringen. Disruption af organisationer er ikke et nyt fænomen; men hastigheden, hvormed det sker, er stadig accelererende. Årsagen er den globale mega-trend: Digitalisering. Og derfor er specielt digital...

  2. Digital books.

    Science.gov (United States)

    Wink, Diane M

    2011-01-01

    In this bimonthly series, the author examines how nurse educators can use the Internet and Web-based computer technologies such as search, communication, and collaborative writing tools; social networking and social bookmarking sites; virtual worlds; and Web-based teaching and learning programs. This article describes digital books.

  3. Digital forvaltning

    DEFF Research Database (Denmark)

    Remmen, Arne; Larsen, Torben; Mosgaard, Mette

    2004-01-01

    Større effektivitet, bedre service og mere demokrai er blot nogle af forventningerne til indførelse af digital forveltning i kommunerne. Kapitlet giver bland andet svar på spørgsmålene : Hvordan lever kommunerne op hertil i dagligdagen? hvilke virkemidler anvender de? Hvilke barrierer har der været...

  4. Digital Methods

    NARCIS (Netherlands)

    Rogers, R.

    2013-01-01

    In Digital Methods, Richard Rogers proposes a methodological outlook for social and cultural scholarly research on the Web that seeks to move Internet research beyond the study of online culture. It is not a toolkit for Internet research, or operating instructions for a software package; it deals

  5. Cluster analysis of commercial samples of Bauhinia spp. using HPLC-UV/PDA and MCR-ALS/PCA without peak alignment procedure.

    Science.gov (United States)

    Ardila, Jorge Armando; Funari, Cristiano Soleo; Andrade, André Marques; Cavalheiro, Alberto José; Carneiro, Renato Lajarim

    2015-01-01

    Bauhinia forficata Link. is recognised by the Brazilian Health Ministry as a treatment of hypoglycemia and diabetes. Analytical methods are useful to assess the plant identity due the similarities found in plants from Bauhinia spp. HPLC-UV/PDA in combination with chemometric tools is an alternative widely used and suitable for authentication of plant material, however, the shifts of retention times for similar compounds in different samples is a problem. To perform comparisons between the authentic medicinal plant (Bauhinia forficata Link.) and samples commercially available in drugstores claiming to be "Bauhinia spp. to treat diabetes" and to evaluate the performance of multivariate curve resolution - alternating least squares (MCR-ALS) associated to principal component analysis (PCA) when compared to pure PCA. HPLC-UV/PDA data obtained from extracts of leaves were evaluated employing a combination of MCR-ALS and PCA, which allowed the use of the full chromatographic and spectrometric information without the need of peak alignment procedures. The use of MCR-ALS/PCA showed better results than the conventional PCA using only one wavelength. Only two of nine commercial samples presented characteristics similar to the authentic Bauhinia forficata spp., considering the full HPLC-UV/PDA data. The combination of MCR-ALS and PCA is very useful when applied to a group of samples where a general alignment procedure could not be applied due to the different chromatographic profiles. This work also demonstrates the need of more strict control from the health authorities regarding herbal products available on the market. Copyright © 2015 John Wiley & Sons, Ltd.

  6. Digital Humanities and networked digital media

    DEFF Research Database (Denmark)

    Finnemann, Niels Ole

    2014-01-01

    This article discusses digital humanities and the growing diversity of digital media, digital materials and digital methods. The first section describes the humanities computing tradition formed around the interpretation of computation as a rule-based process connected to a concept of digital...... materials centred on the digitisation of non-digital, finite works, corpora and oeuvres. The second section discusses “the big tent” of contemporary digital humanities. It is argued that there can be no unifying interpretation of digital humanities above the level of studying digital materials with the help...... of software-supported methods. This is so, in part, because of the complexity of the world and, in part, because digital media remain open to the projection of new epistemologies onto the functional architecture of these media. The third section discusses the heterogeneous character of digital materials...

  7. Digital Materia

    OpenAIRE

    Lindgren, Marcus; Richey, Emma

    2014-01-01

    Med tankar från pedagogen Montessori och filosoferna Platon och Baudrillard har detta arbete behandlat frågor om datorn och dess betydelse för en grafiker. Frågeställningen formulerades efter hand och lydde tillslut: ”Hur kan materia te sig i digital form?” Forskningen resulterade i en hypotes för hur digital materia skulle födas i datorn: genom att blanda två uppsättningar av data, såsom två genuppsättningar tillsammans skapar en ny organism. Under produktionen utvecklades därmed en metod fö...

  8. Digital resources

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2005-12-01

    Full Text Available Bibliotheca Latinitatis Mediaevalis (circa VII sec. - XIV sec. IntraText Digital Library [01/06] Corpus Scriptorum Latinorum. A digital library of Latin literature by David Camden [01/06] Fonti disponibili online concernenti la vita religiosa medievale Rete Vitae Religiosae Mediaevalis Studia Conectens [01/06] Fuentes del Medievo Hispanico Instituto de Historia, Consejo Superior de Investigaciones Científicas [01/06] Latin Literature Forum Romanum [01/06] Ludovico Antonio Muratori, Dissertazioni sopra le antichità italiane, 1751 Biblioteca dei Classici Italiani di Giuseppe Bonghi [01/06] Medieval Latin The Latin Library [01/06] Médiévales Presses Universitaires de Vincennes - Revues.org [01/06] Regesta imperii Deutsche Kommission für die Bearbeitung der Regesta Imperii e.V. [01/06] Suda On Line Byzantine Lexicography [01/06

  9. Digital teenagers

    Directory of Open Access Journals (Sweden)

    Rafael Conde Melguizo

    2011-12-01

    Full Text Available Espín, Manuel (Coord.(2011 Adolescentes Digitales.  Revista Estudios de Juventud, Nº 92. Marzo 2011. INJUVE, Madrid."Adolescentes digitales" se nos muestra como una obra que pretende explorar desde distintos puntos de vista la realidad de la generación conocida como “nativos digitales” (Prensky, la generación actual de adolescentes que ha crecido con internet y el mundo digital como su entorno normal de socialización.

  10. Digital Flora

    OpenAIRE

    Bunnell, Katie

    2007-01-01

    This research is concerned with developing a new business model for flexible small scale ceramic production that exploits the customisation capabilities of digital manufacturing technologies and the market potential and global connectivity of the world wide web. It is arguably of particular relevance to regional economic development in remote areas (Amin, Tomaney, Sabel) such as Cornwall where there is a culture of high quality small scale production, limited market and manufacturing opportun...

  11. L2 writing assistants and context-aware dictionaries: New ...

    African Journals Online (AJOL)

    Dictionaries are increasingly integrated into other tools designed to assist the reading, writing and translation of texts. Write Assistant is a newly developed tool aimed at assisting people writing in a second language. It feeds on big data taken in from corpora and digital dictionaries. The paper discusses the philosophy ...

  12. Results of the combined U.S. Multicenter Pivotal Study and the Continuing Access Study of the Nit-Occlud PDA device for percutaneous closure of patent ductus arteriosus.

    Science.gov (United States)

    Moore, John W; Greene, Jessica; Palomares, Salvadore; Javois, Alexander; Owada, Carl Y; Cheatham, John P; Hoyer, Mark H; Jones, Thomas K; Levi, Daniel S

    2014-12-01

    This study aimed to compare the efficacy and safety of the Nit-Occlud PDA device (PFM Medical, Cologne, Germany) to benchmarks designed as objective performance criteria (OPC). The Nit-Occlud PDA is a nitinol coil-type patent ductus arteriosus (PDA) occluder with a reverse cone configuration, which is implanted using a controlled delivery system. Patients with closure (clinical and echocardiographic), and safety criteria incidence of adverse events (serious and of total). The Pivotal Study enrolled patients between November 1, 2002 and October 31, 2005, and the Continuing Access Study enrolled additional patients between September 1, 2006 and October 31, 2007. A total of 357 patients were enrolled, and 347 had successful device implantations. After 12 months, 96.8% had complete echocardiographic closure (OPC = 85%) and 98.1% had clinical closure (OPC = 95%). There were no deaths or serious adverse events (OPC = 1%). The total adverse event rate was 4.7% (OPC = 6%). Composite success was 95.1% in the study patients (OPC = 80%). Closure of small- and medium-sized PDA with the Nit-Occlud PDA is effective and safe when compared with OPC. Copyright © 2014 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

  13. Crystal violet: Study of the photo-fading of an early synthetic dye in aqueous solution and on paper with HPLC-PDA, LC-MS and FORS

    International Nuclear Information System (INIS)

    Confortin, Daria; Brustolon, Marina; Franco, Lorenzo; Neevel, Han; Bommel, Maarten R van; Kettelarij, Albert J; Williams, Rene M

    2010-01-01

    The photo-fading of crystal violet (CV), one of the earliest synthetic dyes and an ink component, is examined both in solution and on paper. Aqueous solutions of CV were exposed to UV light (365nm) and samples were taken at constant time intervals and analysed with a High Performance Liquid Chromatography-Photo Diode Array (HPLC-PDA) and Liquid Chromatography-Mass Spectroscopy (LC-MS). Demethylation products were positively identified. Also, deamination probably occurred. The oxidation at the central carbon likely generates Michler's ketone (MK) or its derivatives, but still needs confirmation. To study CV on paper, Whatman paper was immersed in CV and exposed to UV light. Before and after different irradiation periods, reflectance spectra were recorded with Fibre Optic Reflectance Spectrophotometry (FORS). A decrease in CV concentration and a change in aggregation type for CV molecules upon irradiation was observed. Colorimetric L*a*b* values before and during irradiation were also measured. Also, CV was extracted from paper before and after different irradiation periods and analysed with HPLC-PDA. Photo-fading of CV on paper produced the same products as in solution, at least within the first 100 hours of irradiation. Finally, a photo-fading of CV in the presence of MK on Whatman paper was performed. It was demonstrated that MK both accelerates CV degradation and is consumed during the reaction. The degradation pathway identified in this work is suitable for explaining the photo/fading of other dyes belonging to the triarylmethane group.

  14. Resveratrol-loaded polymeric nanoparticles: validation of an HPLC-PDA method to determine the drug entrapment and evaluation of its antioxidant activity.

    Science.gov (United States)

    da Rocha Lindner, Gabriela; Khalil, Najeh Maissar; Mainardes, Rubiana Mara

    2013-01-01

    Poly(lactic acid) (PLA) and PLA-poly(ethylene glycol) (PLA-PEG) nanoparticles containing resveratrol (RVT) were developed, and their antioxidant activity was evaluated. An analytical method using high performance liquid chromatography (HPLC)/photodiode array (PDA) detection was also developed and validated for RVT determination in nanoparticles. The mobile phase consisted of methanol : water (51 : 49, v/v) flowed at 0.9 mL/min, and the PDA detector was set at wavelength of 306 nm. The mean diameter of the nanoparticles varied between 180 and 220 nm, and the encapsulation efficiency of RVT ranged from 60% to 88%. The nanoparticles containing RVT were evaluated for their ability to scavenge the radical (2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt) (ABTS•⁺). The profile obtained from the PLA nanoparticles containing RVT demonstrated that after 24 h, there was almost no increase in antioxidant activity, which was lower than that of the free RVT and RVT-loaded PLA-PEG nanoparticles. For PLA-PEG nanoparticles, the radical-scavenging activity of RVT was shown to increase with time, and after 48 h, it was similar to that observed with free RVT.

  15. Resveratrol-Loaded Polymeric Nanoparticles: Validation of an HPLC-PDA Method to Determine the Drug Entrapment and Evaluation of Its Antioxidant Activity

    Directory of Open Access Journals (Sweden)

    Gabriela da Rocha Lindner

    2013-01-01

    Full Text Available Poly(lactic acid (PLA and PLA-poly(ethylene glycol (PLA-PEG nanoparticles containing resveratrol (RVT were developed, and their antioxidant activity was evaluated. An analytical method using high performance liquid chromatography (HPLC/photodiode array (PDA detection was also developed and validated for RVT determination in nanoparticles. The mobile phase consisted of methanol : water (51 : 49, v/v flowed at 0.9 mL/min, and the PDA detector was set at wavelength of 306 nm. The mean diameter of the nanoparticles varied between 180 and 220 nm, and the encapsulation efficiency of RVT ranged from 60% to 88%. The nanoparticles containing RVT were evaluated for their ability to scavenge the radical (2,2-azinobis (3-ethylbenzothiazoline-6-sulfonic acid diammonium salt (ABTS•+. The profile obtained from the PLA nanoparticles containing RVT demonstrated that after 24 h, there was almost no increase in antioxidant activity, which was lower than that of the free RVT and RVT-loaded PLA-PEG nanoparticles. For PLA-PEG nanoparticles, the radical-scavenging activity of RVT was shown to increase with time, and after 48 h, it was similar to that observed with free RVT.

  16. Digital citizens Digital nations: the next agenda

    NARCIS (Netherlands)

    A.W. (Bert) Mulder; M.W. (Martijn) Hartog

    2015-01-01

    DIGITAL CITIZENS CREATE A DIGITAL NATION Citizens will play the lead role as they – in the next phase of the information society – collectively create a digital nation. Personal adoption of information and communication technology will create a digital infrastructure that supports individual and

  17. Graphical User Interface (GUI) for the Warfighter Physiological Status Monitoring (WPSM) System - U.S. Army Medic Recommendations

    National Research Council Canada - National Science Library

    Tharion, William J; Kaushik, Sangeeta

    2006-01-01

    .... This information is sent wirelessly to a personal digital assistant (PDA) held by the medic. The primary purpose of this study was to determine what features should be included in the graphical user interface (GUI...

  18. International assistance. Licensing assistance project

    International Nuclear Information System (INIS)

    Aleev, A.

    1999-01-01

    Description of licensing assistance project for VATESI is presented. In licensing of unit No.1 of INPP VATESI is supported by many western countries. Experts from regulatory bodies or scientific organizations of those countries assist VATESI staff in reviewing documentation presented by INPP. Among bilateral cooperation support is provided by European Commission through Phare programme

  19. Integrating a Hand Held computer and Stethoscope into a Fetal Monitor

    Science.gov (United States)

    Ahmad Soltani, Mitra

    2009-01-01

    This article presents procedures for modifying a hand held computer or personal digital assistant (PDA) into a versatile device functioning as an electronic stethoscope for fetal monitoring. Along with functioning as an electronic stethoscope, a PDA can provide a useful information source for a medical trainee. Feedback from medical students, residents and interns suggests the device is well accepted by medical trainees. PMID:20165517

  20. Die EBM-Datenbank DynaMed für PocketPC und Palm

    Directory of Open Access Journals (Sweden)

    Dollfuß, Helmut

    2007-09-01

    Full Text Available DynaMed is a database for Evidence Based Medicine. Licencee can download a stand-alone version of this database onto their Personal Digital Assistant (PDA. Contents and aims of DynaMed will be introduced. Main features of the PDA-version will be presented and illustrated with screenshots.

  1. Digital fluorimeter

    International Nuclear Information System (INIS)

    Mello, H.A. de.

    1980-11-01

    The specifications of a digital fluorimeter. That with adequated analytical techniques permits to determine trace amounts of fluorescents materials in samples, are described. The fluorimeter is of the reflection type, and uses fluorescents lamps for the excitation and an optical system which is connected to a photomultiplyer machine and permits the measurement of the light intensity. In the case of IEN (Instituto de Engenharia Nuclear) the equipment is used for to determine the uranium content in sample materials to be exported. The precision of the instrument is about + - 1% in the scale of 0.1 which is the normally one used in the current researchs. (E.G.) [pt

  2. Digital entrepreneurship

    DEFF Research Database (Denmark)

    Brem, Alexander; Richter, Chris; Kraus, Sascha

    2017-01-01

    comprising guided interviews with 14 companies from Germany, Austria and Switzerland provides detailed insights into different aspects of the sharing economy phenomenon. Our results make a direct contribution to sharing economy research, especially regarding the new business models of start-ups. Here, we...... find a clear difference between the relevance of economic and social orientation. The latter appears to be in higher demand among customers than entrepreneurs. The increasingly digitalized environment has led to a changed living situation characterized by urbanity, openness to new solutions, changed...

  3. Focus: Digital

    DEFF Research Database (Denmark)

    Technology has been an all-important and defining element within the arts throughout the 20th century, and it has fundamentally changed the ways in which we produce and consume music. With this Focus we investigate the latest developments in the digital domain – and their pervasiveness and rapid...... production and reception of contemporary music and sound art. With ‘Digital’ we present four composers' very different answers to how technology impact their work. To Juliana Hodkinson it has become an integral part of her sonic writing. Rudiger Meyer analyses the relationships between art and design and how...

  4. Digital Humanities

    DEFF Research Database (Denmark)

    Nielsen, Hans Jørn

    2015-01-01

    overgangen fra trykkekultur til digital kultur. For det første problemstillingen omkring digitalisering af litterær kulturarv med fokus på kodning og tagging af teksten samt organisering i hypertekststrukturer. For det andet reorganiseringen af det digitale dokument i dataelementer og database. For det......Artiklen præsenterer først nogle generelle problemstillinger omkring Digital Humanities (DH) med det formål at undersøge dem nærmere i relation til konkrete eksempler på forskellige digitaliseringsmåder og ændringer i dokumentproduktion. I en nærmere afgrænsning vælger artiklen den tendens i DH......, der betragter DH som forbundet med "making" og "building" af digitale objekter og former. Dette kan også karakteriseres som DH som praktisk-produktiv vending. Artiklen har valgt tre typer af digitalisering. De er valgt ud fra, at de skal repræsentere forskellige måder at håndtere digitaliseringen på...

  5. Digital stethoscope: technology update

    Directory of Open Access Journals (Sweden)

    Swarup S

    2018-01-01

    Full Text Available Supreeya Swarup,1 Amgad N Makaryus1,2 1Department of Cardiology, Nassau University Medical Center, East Meadow, NY, 2Department of Cardiology, Zucker School of Medicine at Hofstra/Northwell Health, Hempstead, NY, USA Abstract: Cardiovascular disease (CVD is recognized as the leading cause of mortality throughout the world. About one-third of global mortality is attributable to CVD. In addition to clinical presentation, specific clinical exam findings can assist in treating and preventing CVD. CVD may initially manifest as pulmonary pathology, and thus, accurate cardiopulmonary auscultation is paramount to establishing accurate diagnosis. One of the most powerful tools available to physicians is the stethoscope. The stethoscope first emerged in the year 1818, invented by a French physician, René Laennec. Since then, the initial modest monaural wooden tube has evolved into a sophisticated digital device. This paper provides an analysis of the evolution of the stethoscope as well as highlights the advancement made by the modern digital stethoscope including the application of this tool in advancing care for patients suffering from CVD. Keywords: cardiovascular disease, physical exam, diagnosis, treatment

  6. Flavonoid Composition of Tarocco (Citrus sinensis L. Osbeck) Clone "Lempso" and Fast Antioxidant Activity Screening by DPPH-UHPLC-PDA-IT-TOF.

    Science.gov (United States)

    Sommella, Eduardo; Pagano, Francesco; Pepe, Giacomo; Ostacolo, Carmine; Manfra, Michele; Chieppa, Marcello; Di Sanzo, Rosa; Carabetta, Sonia; Campiglia, Pietro; Russo, Mariateresa

    2017-11-01

    Clonal selection and hybridisation are valid strategies to obtain fruits with enhanced sensorial and nutraceutical properties. Within Citrus sinensis varieties, Tarocco clone "Lempso" is a typical product of the Calabria region (Italy) characterised by its red pulp. This is the first report concerning its accurate profiling. To characterise in detail the flavonoid composition of Lempso clone and to compare its antioxidant potential with other Citrus varieties by a fast screening method. Extracts were subjected to solid phase extraction and the qualitative/quantitative profile was elucidated through ultra-high performance liquid chromatography (UHPLC) coupled to photodiode array (PDA) and ion trap time-of-flight (IT-TOF) mass spectrometry detection, and compared to both Cleopatra mandarin (Citrus reticulata) and blood orange (Citrus sinensis (L.) Osbeck) Sanguinello varieties. The antioxidant activity was assessed by pre-column 2,2'-diphenyl-1-picrylhydrazyl (DPPH) reaction coupled to UHPLC-PDA. Lempso is characterised by flavonoids (17) and anthocyanins (8). Flavanones content (Hesperidin: 57.19 ± 0.49, Vicenin-2: 4.59 ± 0.03, Narirutin: 5.78 ± 0.13 mg/100 mL) was considerably higher than Cleopatra and Sanguinello varieties. The developed DPPH-UHPLC-PDA method provides information regarding the single contributions to antioxidant activity, highlighting how Ferulic acid, Quercetin and Cyanidin derivatives possess considerable radical scavenging activity (> 50%). The total antioxidant activity was also evaluated and compared with positive controls, showing higher scavenging activity than Cleopatra and Sanguinello (IC 50 : 333.76 ± 10.81 μg/mL vs. 452.62 ± 10.81 and 568.39 ± 26.98 μg/mL, respectively). These data evidence the nutraceutical potential of Lempso variety, which could be an ingredient for functional beverages. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  7. A framework about flow measurements by LDA–PDA as a spatio-temporal average: application to data post-processing

    International Nuclear Information System (INIS)

    Calvo, Esteban; García, Juan A; García, Ignacio; Aísa, Luis; Santolaya, José Luis

    2012-01-01

    Phase Doppler anemometry (PDA) is a well-established technique to study two-phase flows and its principles are also used in laser Doppler anemometry (LDA) for measurements of fluid velocity. Raw measurements of individual particle data require post-processing to obtain useful and consistent information (moments of velocity, particle concentration and flux, velocity autocorrelation, etc). This is called in this paper the reconstruction of statistical information. In the 1970s, several basic algorithms to perform the statistical reconstruction were developed for LDA measurements (such as the transit time method, the inverse velocity method, etc). With the advent of PDA, the scientific community developed reconstruction algorithms to obtain mean variables of the dispersed phase. All these basic algorithms were expounded as unconnected methods, following independent threads not integrated into a general framework. Assuming that the PDA works under ideal conditions (all particles that cross the probe volume are validated), this paper provides a general formulation and fully systematizes a large set of previous statistical reconstruction methods. In this paper, the statistical reconstruction of both the dispersed and the continuous phase is unified: the continuous phase post-processing emerges as the same reconstruction method of the dispersed phase. The general framework proposed offers many advantages. First, some previous calculation methods of particle concentration turn out to be particular cases of this general formulation. Second, it provides an easy way to deduce unbiased estimators of any statistical parameter of the flow. Third, a wide set of new post-processing methods are proposed to be tested by any member of the scientific community. In the fourth place, the generalized integral method to compute the particle concentration also gives information about the probe volume geometry and two new auto-calibration algorithms are proposed: the integral calibration

  8. A framework about flow measurements by LDA-PDA as a spatio-temporal average: application to data post-processing

    Science.gov (United States)

    Calvo, Esteban; García, Juan A.; Santolaya, José Luis; García, Ignacio; Aísa, Luis

    2012-05-01

    Phase Doppler anemometry (PDA) is a well-established technique to study two-phase flows and its principles are also used in laser Doppler anemometry (LDA) for measurements of fluid velocity. Raw measurements of individual particle data require post-processing to obtain useful and consistent information (moments of velocity, particle concentration and flux, velocity autocorrelation, etc). This is called in this paper the reconstruction of statistical information. In the 1970s, several basic algorithms to perform the statistical reconstruction were developed for LDA measurements (such as the transit time method, the inverse velocity method, etc). With the advent of PDA, the scientific community developed reconstruction algorithms to obtain mean variables of the dispersed phase. All these basic algorithms were expounded as unconnected methods, following independent threads not integrated into a general framework. Assuming that the PDA works under ideal conditions (all particles that cross the probe volume are validated), this paper provides a general formulation and fully systematizes a large set of previous statistical reconstruction methods. In this paper, the statistical reconstruction of both the dispersed and the continuous phase is unified: the continuous phase post-processing emerges as the same reconstruction method of the dispersed phase. The general framework proposed offers many advantages. First, some previous calculation methods of particle concentration turn out to be particular cases of this general formulation. Second, it provides an easy way to deduce unbiased estimators of any statistical parameter of the flow. Third, a wide set of new post-processing methods are proposed to be tested by any member of the scientific community. In the fourth place, the generalized integral method to compute the particle concentration also gives information about the probe volume geometry and two new auto-calibration algorithms are proposed: the integral calibration

  9. Fechamento de canal arterial por minitoracotomia: técnica e resultados Patent ductus arteriosus (PDA closure with minithoracotomy: technique and results

    Directory of Open Access Journals (Sweden)

    Pedro R. SALERNO

    2000-09-01

    Full Text Available CASUÍSTICA E MÉTODOS: No período de novembro de 1996 a dezembro de 1997, 15 crianças portadoras de canal arterial (CA, sendo 12 do sexo feminino, com idade média de 2,7 anos, peso médio de 13,9 kg foram submetidas a fechamento do CA por minitoracotomia. O ecodopplercardiograma confirmou o diagnóstico em todos o casos e mostrou o diâmetro do CA entre 2 mm e 10 mm, com média de 4,06 mm. A indicação cirúrgica foi eletiva em todos os casos. A operação consistiu de minitoracotomia esquerda no 4º espaço intercostal de 2,5 cm a 3,0 cm, seguida de dissecção do CA e clipagem do mesmo com 2 clips metálicos. Não foi utilizada drenagem pleural em nenhum dos casos. RESULTADOS: Todos os pacientes receberam alta em média no 4º dia de pós-operatório, sem nenhum escape pelo CA ao ecodopplercardiograma. CONCLUSÃO: O fechamento de CA por minitoracotomia é uma alternativa de tratamento que reduz o período de internação, bom efeito cosmético e baixo índice de complicações.OBJECTIVE:The purpose of this study was to describe a new technique for closure of patent ductus arteriosus (PDA by minithoracotomy (2.5 a 3.0 cm and clipping the PDA with titanium clips. MATERIAL AND METHODS: From November 1996 to December 1997, 15 children with PDA underwent surgical closure. The mean age at the time of operation was 2.7 years, mean weight was 13.9 kg. The procedure was through a left minithoracotomy at the 4º intercostal space. The ductus was identified, dissected and isolated. Interruption of ductal flow was performed by direct clipping with two clips. The chest was closed without a chest drain. Unless the patient was ventilator dependent before the closure, the child usually was extubated in the operating room. RESULTS: Color doppler echocardiography demonstrated total occlusion of the ductus in all patients. All 15 patients were discharged from the hospital on the 4º postoperative day (mean. CONCLUSION: We conclude that surgical closure of

  10. [Impact of digital technology on clinical practices: perspectives from surgery].

    Science.gov (United States)

    Zhang, Y; Liu, X J

    2016-04-09

    Digital medical technologies or computer aided medical procedures, refer to imaging, 3D reconstruction, virtual design, 3D printing, navigation guided surgery and robotic assisted surgery techniques. These techniques are integrated into conventional surgical procedures to create new clinical protocols that are known as "digital surgical techniques". Conventional health care is characterized by subjective experiences, while digital medical technologies bring quantifiable information, transferable data, repeatable methods and predictable outcomes into clinical practices. Being integrated into clinical practice, digital techniques facilitate surgical care by improving outcomes and reducing risks. Digital techniques are becoming increasingly popular in trauma surgery, orthopedics, neurosurgery, plastic and reconstructive surgery, imaging and anatomic sciences. Robotic assisted surgery is also evolving and being applied in general surgery, cardiovascular surgery and orthopedic surgery. Rapid development of digital medical technologies is changing healthcare and clinical practices. It is therefore important for all clinicians to purposefully adapt to these technologies and improve their clinical outcomes.

  11. Digital radiography

    DEFF Research Database (Denmark)

    Precht, H; Gerke, O; Rosendahl, K

    2012-01-01

    BACKGROUND: New developments in processing of digital radiographs (DR), including multi-frequency processing (MFP), allow optimization of image quality and radiation dose. This is particularly promising in children as they are believed to be more sensitive to ionizing radiation than adults....... OBJECTIVE: To examine whether the use of MFP software reduces the radiation dose without compromising quality at DR of the femur in 5-year-old-equivalent anthropomorphic and technical phantoms. MATERIALS AND METHODS: A total of 110 images of an anthropomorphic phantom were imaged on a DR system (Canon DR...... with CXDI-50 C detector and MLT[S] software) and analyzed by three pediatric radiologists using Visual Grading Analysis. In addition, 3,500 images taken of a technical contrast-detail phantom (CDRAD 2.0) provide an objective image-quality assessment. RESULTS: Optimal image-quality was maintained at a dose...

  12. Fokus: Digital

    DEFF Research Database (Denmark)

    2014-01-01

    i det digitale domæne – udviklinger, der foregår hastigt og er gennemgribende, og som derfor kræver et nærmere blik på forholdet mellem kunsten og teknologien. Komponistens forståelse af sin metier udfordres – samtidig med at befæstede ideer om kunstværket møder modstand fra nye mediemæssige...... sammenhænge og fra forandrede distributionsformer. Dette betyder ændrede betingelser for både produktion og reception af kunstmusik og lydkunst. Med Digital tager vi udgangspunkt i fire komponisters meget forskellige bud på hvordan teknologien spiller en rolle i arbejdet. Juliana Hodkinson beskriver hvordan...

  13. HPLC-PDA Combined with Chemometrics for Quantitation of Active Components and Quality Assessment of Raw and Processed Fruits of Xanthium strumarium L.

    Science.gov (United States)

    Jiang, Hai; Yang, Liu; Xing, Xudong; Yan, Meiling; Guo, Xinyue; Yang, Bingyou; Wang, Qiuhong; Kuang, Haixue

    2018-01-25

    As a valuable herbal medicine, the fruits of Xanthium strumarium L. (Xanthii Fructus) have been widely used in raw and processed forms to achieve different therapeutic effects in practice. In this study, a comprehensive strategy was proposed for evaluating the active components in 30 batches of raw and processed Xanthii Fructus (RXF and PXF) samples, based on high-performance liquid chromatography coupled with photodiode array detection (HPLC-PDA). Twelve common peaks were detected and eight compounds of caffeoylquinic acids were simultaneously quantified in RXF and PXF. All the analytes were detected with satisfactory linearity (R² > 0.9991) over wide concentration ranges. Simultaneously, the chemically latent information was revealed by hierarchical cluster analysis (HCA) and principal component analysis (PCA). The results suggest that there were significant differences between RXF and PXF from different regions in terms of the content of eight caffeoylquinic acids. Potential chemical markers for XF were found during processing by chemometrics.

  14. HPLC-PDA Combined with Chemometrics for Quantitation of Active Components and Quality Assessment of Raw and Processed Fruits of Xanthium strumarium L.

    Directory of Open Access Journals (Sweden)

    Hai Jiang

    2018-01-01

    Full Text Available As a valuable herbal medicine, the fruits of Xanthium strumarium L. (Xanthii Fructus have been widely used in raw and processed forms to achieve different therapeutic effects in practice. In this study, a comprehensive strategy was proposed for evaluating the active components in 30 batches of raw and processed Xanthii Fructus (RXF and PXF samples, based on high-performance liquid chromatography coupled with photodiode array detection (HPLC-PDA. Twelve common peaks were detected and eight compounds of caffeoylquinic acids were simultaneously quantified in RXF and PXF. All the analytes were detected with satisfactory linearity (R2 > 0.9991 over wide concentration ranges. Simultaneously, the chemically latent information was revealed by hierarchical cluster analysis (HCA and principal component analysis (PCA. The results suggest that there were significant differences between RXF and PXF from different regions in terms of the content of eight caffeoylquinic acids. Potential chemical markers for XF were found during processing by chemometrics.

  15. Determination of flavonoids, phenolic acid and polyalcohol in Butea monosperma and Hedychium coronarium by semi-preparative HPLC Photo Diode Array (PDA Detector

    Directory of Open Access Journals (Sweden)

    Jignasu P. Mehta

    2014-12-01

    Full Text Available The semi preparative HPLC method with PDA Detector was proposed for the determination of one phenolic acid, three flavonoids and one polyalcohol from Butea monosperma and Hedychium coronarium in gradient elution system. The influence of composition of the mobile phase concentration of the mix modifier and temperature on the separation of gallic acid, quercetin, iso-butrin, butrin and eugenol for 90 min was studied. Two different gradient programmes were used to separate these components. The lower limit of quantification of phenolic acid, flavonoids and eugenol is 0.050–0.150 μg/mL and was determined by the least square method and a good correlation was obtained for all separated components.

  16. The Digital Divide: The Special Case of Gender

    Science.gov (United States)

    Cooper, J.

    2006-01-01

    This paper examines the evidence for the digital divide based on gender. An overview of research published in the last 20 years draws to the conclusion that females are at a disadvantage relative to men when learning about computers or learning other material with the aid of computer-assisted software. The evidence shows that the digital divide…

  17. Computer aided site management. Site use management by digital mapping

    International Nuclear Information System (INIS)

    Chupin, J.C.

    1990-01-01

    The logistics program developed for assisting the Hague site management is presented. A digital site mapping representation and geographical data bases are used. The digital site map and its integration into a data base are described. The program can be applied to urban and rural land management aid. Technical administrative and economic evaluations of the program are summarized [fr

  18. Protest: Critical Lessons of Using Digital Media for Social Change

    Science.gov (United States)

    LaRiviere, Kristin; Snider, Jeanette; Stromberg, Alison; O'Meara, KerryAnn

    2012-01-01

    In this article, the authors consider the strengths and weaknesses of digital media in the organization of student activism, and how educators can better assist and advise student activists using digital media to create improved learning opportunities. To gain a perspective on the relative strengths and challenges of online media in regard to…

  19. Antioxidant Properties and Hyphenated HPLC-PDA-MS Profiling of Chilean Pica Mango Fruits (Mangifera indica L. Cv. piqueño

    Directory of Open Access Journals (Sweden)

    Javier E. Ramirez

    2013-12-01

    Full Text Available Antioxidant capacities and polyphenolic contents of two mango cultivars from northern Chile, one of them endemic of an oasis in the Atacama Desert, were compared for the first time. Twenty one phenolic compounds were detected in peel and pulp of mango fruits varieties Pica and Tommy Atkins by HPLC-PDA-MS and tentatively characterized. Eighteen compounds were present in Pica pulp (ppu, 13 in Pica peel (ppe 11 in Tommy Atkins pulp (tpu and 12 in Tommy Atkins peel (tpe. Three procyanidin dimers (peaks 6, 9 and 10, seven acid derivatives (peaks 1–4, 11, 20 and 21 and four xanthones were identified, mainly mangiferin (peak 12 and mangiferin gallate, (peak 7, which were present in both peel and pulp of the two studied species from northern Chile. Homomangiferin (peak 13 was also present in both fruit pulps and dimethylmangiferin (peak 14 was present only in Tommy pulp. Pica fruits showed better antioxidant capacities and higher polyphenolic content (73.76/32.23 µg/mL in the DPPH assay and 32.49/72.01 mg GAE/100 g fresh material in the TPC assay, for edible pulp and peel, respectively than Tommy Atkins fruits (127.22/46.39 µg/mL in the DPPH assay and 25.03/72.01 mg GAE/100 g fresh material in the TPC assay for pulp and peel, respectively. The peel of Pica mangoes showed also the highest content of phenolics (66.02 mg/100 g FW measured by HPLC-PDA. The HPLC generated fingerprint can be used to authenticate Pica mango fruits and Pica mango food products.

  20. Antioxidant properties and hyphenated HPLC-PDA-MS profiling of Chilean Pica mango fruits (Mangifera indica L. Cv. piqueño).

    Science.gov (United States)

    Ramirez, Javier E; Zambrano, Ricardo; Sepúlveda, Beatriz; Simirgiotis, Mario J

    2013-12-31

    Antioxidant capacities and polyphenolic contents of two mango cultivars from northern Chile, one of them endemic of an oasis in the Atacama Desert, were compared for the first time. Twenty one phenolic compounds were detected in peel and pulp of mango fruits varieties Pica and Tommy Atkins by HPLC-PDA-MS and tentatively characterized. Eighteen compounds were present in Pica pulp (ppu), 13 in Pica peel (ppe) 11 in Tommy Atkins pulp (tpu) and 12 in Tommy Atkins peel (tpe). Three procyanidin dimers (peaks 6, 9 and 10), seven acid derivatives (peaks 1-4, 11, 20 and 21) and four xanthones were identified, mainly mangiferin (peak 12) and mangiferin gallate, (peak 7), which were present in both peel and pulp of the two studied species from northern Chile. Homomangiferin (peak 13) was also present in both fruit pulps and dimethylmangiferin (peak 14) was present only in Tommy pulp. Pica fruits showed better antioxidant capacities and higher polyphenolic content (73.76/32.23 µg/mL in the DPPH assay and 32.49/72.01 mg GAE/100 g fresh material in the TPC assay, for edible pulp and peel, respectively) than Tommy Atkins fruits (127.22/46.39 µg/mL in the DPPH assay and 25.03/72.01 mg GAE/100 g fresh material in the TPC assay for pulp and peel, respectively). The peel of Pica mangoes showed also the highest content of phenolics (66.02 mg/100 g FW) measured by HPLC-PDA. The HPLC generated fingerprint can be used to authenticate Pica mango fruits and Pica mango food products.

  1. Digital work in a digitally challenged organization

    NARCIS (Netherlands)

    Davison, R.M.; Ou, Carol

    Digitally literate employees are accustomed to having free access to digital media technologies. However, some organizations enact information technology (IT) governance structures that explicitly proscribe access to these technologies, resulting in considerable tension between employees and the

  2. A Study of Applying Digital Mobile Museum Guide

    Directory of Open Access Journals (Sweden)

    Chao-yun Chaucer Liang

    2003-09-01

    Full Text Available With the prosperous development of information technology, museums begin to apply new technology to enhance operation and communication efficiency. One of the information technology. Personal Digital Mobile, featuring light weight and mobility, can help museum to set up an interactive navigation system, which offering capability of user-controlled guidance and both broad and depth information. In this study, literature related to museum tour guide, digital mobile navigation, and multimedia interaction design were reviewed, and two examples were offered for reference. The first one example is Exploratorium in American, which is cooperated with HP labs to integrate wireless networking and PDA devices. The domestic example is the design project of the Personal Digital Mobile Guide for the Emperor Ch’ien-lung’s Grand Cultural Enterprise Exhibition in National Palace Museum, 2002. This paper introduces the techniques involved, interactive storyboard, interface design, color planning, electronic element planning, etc. The process of applying theory into creative project may help future researches in the related areas.[Article content in Chinese

  3. Inception Report, Photogrammetry and Digital Mapping, LATIVA

    DEFF Research Database (Denmark)

    Frederiksen, Poul

    1996-01-01

    The report gives the current situation on photogrammetry and digital mapping by the end of 1996 in Latvia.Objectives and proposals are given for activities of the EU Phare project: Technical Assistance to Land Privatisation and Registration in Latvia.The project is executed by Kampsax Geoplan...

  4. USNA DIGITAL FORENSICS LAB

    Data.gov (United States)

    Federal Laboratory Consortium — To enable Digital Forensics and Computer Security research and educational opportunities across majors and departments. Lab MissionEstablish and maintain a Digital...

  5. Can We Teach Digital Natives Digital Literacy?

    Science.gov (United States)

    Ng, Wan

    2012-01-01

    In recent years, there has been much debate about the concept of digital natives, in particular the differences between the digital natives' knowledge and adoption of digital technologies in informal versus formal educational contexts. This paper investigates the knowledge about educational technologies of a group of undergraduate students…

  6. Simultaneous determination of aegeline and six coumarins from different parts of the plant Aegle marmelos using UHPLC-PDA-MS and chiral separation of aegeline using HPLC-ToF-MS

    Science.gov (United States)

    A fast UHPLC-PDA method was developed for the simultaneous analysis of one alkaloid, aegeline, and six coumarins namely: umbelliferone; scopoletin; marmesinin; 8-hydroxypsoralen angelicin and marmelosin from leaf, fruit, root and bark of Aegle marmelos (L.) Corrêa (Rutaceae). The method was validate...

  7. Computer-assisted nuclear fuel manufacture

    International Nuclear Information System (INIS)

    Maloney, J.P.; Schaumann, S.M.; Stone, E.

    1976-01-01

    At the ERDA Savannah River Plant, a process monitor, which incorporates an online digital computer, assists in manufacturing fuel elements used to produce nuclides such as plutonium, tritium, and californium in the plant's nuclear reactors. Also, inventory functions assist in safeguarding fissile material and protecting against accidental nuclear criticality. Terminals at strategic locations throughout the process area enable production operators to send and receive instructions and information on each manufacturing step

  8. Computer-assisted nuclear fuel manufacture

    International Nuclear Information System (INIS)

    Maloney, J.P.; Schaumann, C.M.; Stone, E.

    1976-06-01

    At the ERDA Savannah River Plant, a process monitor, which incorporates an online digital computer, assists in manufacturing fuel elements used to produce nuclides such as plutonium, tritium, and californium in the plant's nuclear reactors. Also, inventory functions assist in safeguarding fissile material and protecting against accidental nuclear criticality. Terminals at strategic locations throughout the process area enable production operators to send and receive instructions and information on each manufacturing step. 11 fig

  9. Assisted Living

    Science.gov (United States)

    ... a resident's needs depends as much on the philosophy and services of the assisted living facility as it does on the quality of care. The Administration on Aging, a part of the U.S. Department of Health and Human Services (HHS), offers these suggestions to help you ...

  10. Assistive Devices

    Science.gov (United States)

    If you have a disability or injury, you may use a number of assistive devices. These are tools, products or types of equipment that help you perform tasks and activities. They may help you move around, see, communicate, eat, or get ...

  11. Digital produktion

    DEFF Research Database (Denmark)

    Bogen sætter fokus på digital produktion, som er en stærk læringsform, der faciliterer elevernes læreprocesser og kvalificerer elevernes faglige læringsresultater. Det sker når lærerne udarbejder didaktiske rammedesign, hvor eleverne arbejder selvstændigt inden for dette rammedesign, og hvor mål og...... procesevaluering stilladserer elevernes faglige proces. I digitale produktionsprocesser arbejder eleverne iterativt, de udvikler ejerskab til produktionen og fastholder selv deres læreprocesser. It’s multimodalitet, elevernes kollaborative tilgange, videndeling mellem eleverne og elevernes uformelle lege- og...... elevernes digitale produktion er lærernes didaktiske rammesætning og stilladserende tilgange. Her lægger lærerne op til, at eleverne som didaktiske designere i relation til rammesætningen skal organisere og planlægge deres læreprocesser, inddrages i målsætning, evaluering og valg af digitale ressourcer...

  12. Digital dannelse

    DEFF Research Database (Denmark)

    Bundsgaard, Jeppe

    2012-01-01

    I al vores iver efter at få presset nogle flere digitale dimser ind i skolen, er vi i fare for at glemme hvad det er vi skal med disse dimser. Der er store forventninger til at de kan gøre det lettere at være lærer (og dermed billigere), og det kan det måske. Men der er jo også et dannelsesspørgs......I al vores iver efter at få presset nogle flere digitale dimser ind i skolen, er vi i fare for at glemme hvad det er vi skal med disse dimser. Der er store forventninger til at de kan gøre det lettere at være lærer (og dermed billigere), og det kan det måske. Men der er jo også et...... dannelsesspørgsmål knyttet til it. Hvad er egentlig digital dannelse? Og hvad betyder det for danskfaget?...

  13. Digital forensics digital evidence in criminal investigations

    CERN Document Server

    Marshall, Angus McKenzie

    2009-01-01

    The vast majority of modern criminal investigations involve some element of digital evidence, from mobile phones, computers, CCTV and other devices. Digital Forensics: Digital Evidence in Criminal Investigations provides the reader with a better understanding of how digital evidence complements "traditional" scientific evidence and examines how it can be used more effectively and efficiently in a range of investigations. Taking a new approach to the topic, this book presents digital evidence as an adjunct to other types of evidence and discusses how it can be deployed effectively in s

  14. Digital platforms as enablers for digital transformation

    DEFF Research Database (Denmark)

    Hossain, Mokter; Lassen, Astrid Heidemann

    transformation is crucial. This study aims at exploring how organizations are driven towards transformation in various ways to embrace digital platforms for ideas, technologies, and knowledge. It shows the opportunities and challenges digital platforms bring in organizations. It also highlights underlying......Digital platforms offer new ways for organizations to collaborate with the external environment for ideas, technologies, and knowledge. They provide new possibilities and competence but they also bring new challenges for organizations. Understanding the role of these platforms in digital...... mechanisms and potential outcomes of various digital platforms. The contribution of the submission is valuable for scholars to understand and further explore this area. It provides insight for practitioners to capture value through digital platforms and accelerate the pace of organizations’ digital...

  15. Book Review: The Basics of Digital Forensics: The Primer for Getting Started in Digital Forensics

    Directory of Open Access Journals (Sweden)

    Stephen Larson

    2014-03-01

    Full Text Available Sammons, John. (2012. The Basics of Digital Forensics: The Primer for Getting Started in Digital Forensics. Waltham, MA: Syngress, 208 pages, Print Book ISBN: 9781597496612.eBook ISBN : 9781597496629. Print: US $29.95. eBook: US$20.97. Includes exercises, case studies, references, and index.Reviewed by Stephen Larson, PhD. Assistant Professor, Slippery Rock University of PAThe Basics of Digital Forensics: The Primer for Getting Started in Digital Forensics is well-named–it really is very basic. And it should be, as the book’s intended audience includes entry-level digital forensics professionals and complimentary fields such as law enforcement, legal, and general information security. Though the copyright is 2012, some of the data is from 2009, and there is mention of estimates for 2010.(see PDF for full review

  16. H. Sapiens Digital: From Digital Immigrants and Digital Natives to Digital Wisdom

    Science.gov (United States)

    Prensky, Marc

    2009-01-01

    As we move further into the 21st century, the digital native/digital immigrant paradigm created by Marc Prensky in 2001 is becoming less relevant. In this article, Prensky suggests that we should focus instead on the development of what he calls "digital wisdom." Arguing that digital technology can make us not just smarter but truly wiser, Prensky…

  17. Dual beam vidicon digitizer

    International Nuclear Information System (INIS)

    Evans, T.L.

    1976-01-01

    A vidicon waveform digitizer which can simultaneously digitize two independent signals has been developed. Either transient or repetitive waveforms can be digitized with this system. A dual beam oscilloscope is used as the signal input device. The light from the oscilloscope traces is optically coupled to a television camera, where the signals are temporarily stored prior to digitizing

  18. Foreign assistance

    International Nuclear Information System (INIS)

    1991-07-01

    This paper reports that providing energy assistance to developing countries remains a relatively low priority of the Agency for International Development. AID is helping some developing countries meet their energy needs, but this assistance varies substantially because of the agency's decentralized structure. Most AID energy funding has gone to a handful of countries-primarily Egypt and Pakistan. With limited funding in most other countries, AID concentrates on providing technical expertise and promoting energy policy reforms that will encourage both energy efficiency and leverage investment by the private sector and other donors. Although a 1989 congressional directive to pursue a global warming initiative has had a marginal impact on the agency's energy programming, many AID energy programs, including those directed at energy conservation, help address global warming concerns

  19. Enabling Digital Literacy

    DEFF Research Database (Denmark)

    Ryberg, Thomas; Georgsen, Marianne

    2010-01-01

    There are some tensions between high-level policy definitions of “digital literacy” and actual teaching practice. We need to find workable definitions of digital literacy; obtain a better understanding of what digital literacy might look like in practice; and identify pedagogical approaches, which...... support teachers in designing digital literacy learning. We suggest that frameworks such as Problem Based Learning (PBL) are approaches that enable digital literacy learning because they provide good settings for engaging with digital literacy. We illustrate this through analysis of a case. Furthermore......, these operate on a meso-level mediating between high-level concepts of digital literacy and classroom practice....

  20. Progress in digital radiography

    International Nuclear Information System (INIS)

    Cappelle, A.

    2016-01-01

    Because of its practical aspect digital radiography is more and more used in the industrial sector. There are 2 kinds of digital radiography. First, the 'computed radiography' that uses a photon-stimulated screen, and after radiation exposure this screen must be read by an analyser to get a digit image. The second type is the 'direct radiography' that allows one to get a digit radiograph of the object directly. Digital radiography uses the same radioactive nuclides as radiography with silver films: cobalt, iridium or selenium. The spatial resolution of digital radiography is less good than with classical silver film radiography but digital radiography offers a better visual contrast. (A.C.)

  1. 76 FR 41293 - Solicitation of Proposals for Technical Assistance Funding From the Native American Business...

    Science.gov (United States)

    2011-07-13

    ... for NABDI Technical Assistance Funding D. Submission of Application in Digital Format E. Application.... The IEED has spent considerable time and expense in collecting digital land grids, geographic...: Marketing studies. 9. What the NABDI Technical Assistance Funding Cannot Fund As stated above, these funds...

  2. Digital Sensor Technology

    Energy Technology Data Exchange (ETDEWEB)

    Ted Quinn; Jerry Mauck; Richard Bockhorst; Ken Thomas

    2013-07-01

    The nuclear industry has been slow to incorporate digital sensor technology into nuclear plant designs due to concerns with digital qualification issues. However, the benefits of digital sensor technology for nuclear plant instrumentation are substantial in terms of accuracy, reliability, availability, and maintainability. This report demonstrates these benefits in direct comparisons of digital and analog sensor applications. It also addresses the qualification issues that must be addressed in the application of digital sensor technology.

  3. Digital preservation for heritages

    CERN Document Server

    Lu, Dongming

    2011-01-01

    ""Digital Preservation for Heritages: Technologies and Applications"" provides a comprehensive and up-to-date coverage of digital technologies in the area of cultural heritage preservation, including digitalization, research aiding, conservation aiding, digital exhibition, and digital utilization. Processes, technical frameworks, key technologies, as well as typical systems and applications are discussed in the book. It is intended for researchers and students in the fields of computer science and technology, museology, and archaeology. Dr. Dongming Lu is a professor at College of Computer Sci

  4. Scaffolding in Assisted Instruction

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available On-The-Job Training, developed as direct instruction, is one of the earliest forms of training. This method is still widely in use today because it requires only a person who knows how to do the task, and the tools the person uses to do the task. This paper is intended to be a study of the methods used in education in Knowledge Society, with more specific aspects in training the trainers; as a result of this approach, it promotes scaffolding in assisted instruction as a reflection of the digital age for the learning process. Training the trainers in old environment with default techniques and designing the learning process in assisted instruction, as an application of the Vygotskian concept of the zone of proximal development (ZPD to the area of computer literacy for the younger users, generate diversity in educational communities and requires standards for technology infrastructure, standards for the content, developed as a concepts map, and applications for personalized in-struction, based on ZPD theory.

  5. Feeding assistive robotics, imaginaries and care

    DEFF Research Database (Denmark)

    Nickelsen, Niels Christian Mossfeldt

    2018-01-01

    The media and political/managerial levels focus on the opportunities to re-perform Denmark through digitization. Feeding assistive robotics is a welfare technology, relevant to citizens with low or no function in their arms. Despite national dissemination strategies, it proves difficult to recruit...

  6. Engaging Digital Natives through Social Learning

    Directory of Open Access Journals (Sweden)

    Nina Sarkar

    2017-04-01

    Full Text Available Digital natives account for a substantial portion of the total enrollment in higher education. This calls for significant educational reforms because traditional education systems do not cater to the needs and interests of digital natives. The most effective way that both students and instructors can benefit from this paradigm shift is to integrate technology that is appropriate to the cognitive learning patterns of the digital natives into the curriculum. This paper builds upon previous research in technology/personality theory and specifically attempts to provide examples of technology that will address the instructional needs of digital natives. Further this paper provides empirical evidence of the impact of technology integration on the learning outcomes of digital natives. In this study, the authors explored the impact of targeted technology on academic performance in three businesses courses. Three functional technologies were used by the authors to build engaging course content, efficiently manage course content, and to interact with digital native students. This study found that these technologies can assist digital natives in the learning process and lead to better academic performance.

  7. Cognitive Hacking and Digital Government: Digital Identity

    OpenAIRE

    Paul Thompson

    2004-01-01

    Recently the National Center for Digital Government held a workshop on "The Virtual Citizen: Identity, Autonomy, and Accountability: A Civic Scenario Exploration of the Role of Identity in On-Line. Discussions at the workshop focused on five scenarios for future authentication policies with respect to digital identity. The underlying technologies considered for authentication were: biometrics: cryptography, with a focus on digital signatures; secure processing/computation; and reputation syst...

  8. Digital Materialisms: Frameworks for Digital Media Studies

    OpenAIRE

    Casemajor, Nathalie

    2015-01-01

    Since the 1980s, digital materialism has received increasing interest in the field of media studies. Materialism as a theoretical paradigm assumes that all things in the world are tied to physical processes and matter. Yet within digital media studies, the understanding of what should be the core object of a materialist analysis is debated. This paper proposes to untangle some of the principal theoretical propositions that compose the field of digital materialism. It outlines six frameworks t...

  9. Computer assisted radiology and surgery. CARS 2010

    International Nuclear Information System (INIS)

    Anon.

    2010-01-01

    The conference proceedings include contributions to the following topics: (1) CARS Clinical Day: minimally invasive spiral surgery, interventional radiology; (2) CARS - computer assisted radiology and surgery: ophthalmology, stimulation methods, new approaches to diagnosis and therapy; (3) Computer assisted radiology 24th International congress and exhibition: computer tomography and magnetic resonance, digital angiographic imaging, digital radiography, ultrasound, computer assisted radiation therapy, medical workstations, image processing and display; (4) 14th Annual conference of the International Society for computer aided surgery; ENT-CMF head and neck surgery computer-assisted neurosurgery, cardiovascular surgery, image guided liver surgery, abdominal and laparoscopic surgery, computer-assisted orthopedic surgery, image processing and visualization, surgical robotics and instrumentation, surgical modeling, simulation and education; (5) 28th International EuroPACS meeting: image distribution and integration strategies, planning and evaluation, telemedicine and standards, workflow and data flow in radiology; (6) 11th CARS/SPIE/EuroPACS joint workshop on surgical PACS and the digital operating, management and assessment of OR systems and integration; (7) 12th International workshop on computer-aided diagnosis: special session on breast CAD, special session on thoracic CAD, special session on abdominal brain, lumbar spine CAD; (8) 16th computed Maxillofacial imaging congress: computed maxillofacial imaging in dental implantology, orthodontics and dentofacial orthopedics; approaches to 3D maxillofacial imaging; surgical navigation; (9) 2nd EuroNOTES/CARS workshop on NOTES: an interdisciplinary challenge; (10) 2nd EPMA/CARS workshop on personalized medicine and ICT.; (11)poster sessions.

  10. Computer assisted radiology and surgery. CARS 2010

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2010-06-15

    The conference proceedings include contributions to the following topics: (1) CARS Clinical Day: minimally invasive spiral surgery, interventional radiology; (2) CARS - computer assisted radiology and surgery: ophthalmology, stimulation methods, new approaches to diagnosis and therapy; (3) Computer assisted radiology 24th International congress and exhibition: computer tomography and magnetic resonance, digital angiographic imaging, digital radiography, ultrasound, computer assisted radiation therapy, medical workstations, image processing and display; (4) 14th Annual conference of the International Society for computer aided surgery; ENT-CMF head and neck surgery computer-assisted neurosurgery, cardiovascular surgery, image guided liver surgery, abdominal and laparoscopic surgery, computer-assisted orthopedic surgery, image processing and visualization, surgical robotics and instrumentation, surgical modeling, simulation and education; (5) 28th International EuroPACS meeting: image distribution and integration strategies, planning and evaluation, telemedicine and standards, workflow and data flow in radiology; (6) 11th CARS/SPIE/EuroPACS joint workshop on surgical PACS and the digital operating, management and assessment of OR systems and integration; (7) 12th International workshop on computer-aided diagnosis: special session on breast CAD, special session on thoracic CAD, special session on abdominal brain, lumbar spine CAD; (8) 16th computed Maxillofacial imaging congress: computed maxillofacial imaging in dental implantology, orthodontics and dentofacial orthopedics; approaches to 3D maxillofacial imaging; surgical navigation; (9) 2nd EuroNOTES/CARS workshop on NOTES: an interdisciplinary challenge; (10) 2nd EPMA/CARS workshop on personalized medicine and ICT.; (11)poster sessions.

  11. Scheduling Accessory Assists Patients with Cognitive Disorders

    Science.gov (United States)

    2007-01-01

    Recom Technologies Inc. received initial funding from NASA to research the commercial potential of an artificially intelligent planning reaction model to serve as a tool to help individuals suffering from various forms and levels of brain impairment. In 1993, the chief of the Artificial Intelligence Research Branch at Ames Research Center suggested collaborative research with Santa Clara Valley Medical Center. This partnership led to further development of the technology and funding to support clinical research from the U.S. Department of Education's National Institute on Disability and Rehabilitation Research. In 1996, Attention Control Systems Inc. was founded to market the finished device, called the Planning and Execution Assistant and Trainer (PEAT). PEAT is a pocket-sized PDA-like device with a graphical display, touchscreen controls, an electronic calendar, an address book, and a built-in phone, that cues users to start or stop scheduled activities, monitors their progress, and adjusts schedules as necessary in response to delays or calendar changes. It uses an automatic planning model developed for NASA to adjust daily plans when a situation changes. PEAT is sold as a complete system that includes software, hardware, documentation, and technical support. In addition to the flagship Pocket PEAT device, there is PEAT Phone, PC PEAT, and PEAT Link. Clinical studies of PEAT continue at Santa Clara Valley Medical Center

  12. Phytochemical, antioxidant and antidiabetic evaluation of eight Bauhinia L. species from Egypt using UHPLC-PDA-qTOF-MS and chemometrics.

    Science.gov (United States)

    Farag, Mohamed A; Sakna, Sarah T; El-Fiky, Nabaweya M; Shabana, Marawan M; Wessjohann, Ludger A

    2015-11-01

    Bauhinia L. (Fabaceae) comprises ca. 300-350 plant species, many of which are traditionally used in folk medicine for their antidiabetic, antioxidant and anti-inflammatory effects. Bauhinia s.l. recently has been subdivided into 9 genera based on phylogenetic data: Bauhinia s.str., Barklya, Brenierea, Gigasiphon, Lysiphyllum, Phanera, Piliostigma, Schnella (American Phanera) and Tylosema. The aerial parts of 8 species corresponding to 5 genera were analyzed: Bauhinia forficata, Bauhinia variegata, B. variegata var. candida, Bauhinia galpinii, Schnella glabra, Piliostigma racemosa, Phanera vahlii and Lysiphyllum hookeri. Leaves and shoots were subjected to metabolite profiling via UHPLC-PDA-qTOF-MS coupled to multivariate data analyzes to identify compound compositional differences. A total of 90 metabolites were identified including polyphenols and fatty acids; flavonoid conjugates accounted for most of the metabolite variation observed. This study provides a comprehensive map of polyphenol composition in Bauhinia and phytochemical species aggregations are consistent with recent Bauhinia genus taxonomic relationship derived from phylogenetic studies. DPPH radical scavenging and α-glucosidase inhibitory assays were also performed to assess selected aspects of the antioxidant and antidiabetic potential for the examined species with respect to metabolite profiles. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Fast UPLC/PDA determination of squalene in Sicilian P.D.O. pistachio from Bronte: Optimization of oil extraction method and analytical characterization.

    Science.gov (United States)

    Salvo, Andrea; La Torre, Giovanna Loredana; Di Stefano, Vita; Capocchiano, Valentina; Mangano, Valentina; Saija, Emanuele; Pellizzeri, Vito; Casale, Katia Erminia; Dugo, Giacomo

    2017-04-15

    A fast reversed-phase UPLC method was developed for squalene determination in Sicilian pistachio samples that entry in the European register of the products with P.D.O. In the present study the SPE procedure was optimized for the squalene extraction prior to the UPLC/PDA analysis. The precision of the full analytical procedure was satisfactory and the mean recoveries were 92.8±0.3% and 96.6±0.1% for 25 and 50mgL -1 level of addition, respectively. Selected chromatographic conditions allowed a very fast squalene determination; in fact it was well separated in ∼0.54min with good resolution. Squalene was detected in all the pistachio samples analyzed and the levels ranged from 55.45-226.34mgkg -1 . Comparing our results with those of other studies it emerges that squalene contents in P.D.O. Sicilian pistachio samples, generally, were higher than those measured for other samples of different geographic origins. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Errors analysis in the evaluation of particle concentration by PDA on a turbulent two-phase jet: application for cross section and transit time methods

    Science.gov (United States)

    Calvo, Esteban; García, Juan A.; García, Ignacio; Aísa, Luis A.

    2009-09-01

    Phase-Doppler anemometry (PDA) is a powerful tool for two-phase flow measurements and testing. Particle concentration and mass flux can also be evaluated using the raw particle data supplied by this technique. The calculation starts from each particle velocity, diameter, transit time data, and the total measurement time. There are two main evaluation strategies. The first one uses the probe volume effective cross section, and it is usually simplified assuming that particles follow quasi one-directional trajectories. In the text, it will be called the cross section method. The second one includes a set of methods which will be denoted as “Generalized Integral Methods” (GIM). Concentration algorithms such as the transit time method (TTM) and the integral volume method (IVM) are particular cases of the GIM. In any case, a previous calibration of the measurement volume geometry is necessary to apply the referred concentration evaluation methods. In this study, concentrations and mass fluxes both evaluated by the cross-section method and the TTM are compared. Experimental data are obtained from a particle-laden jet generated by a convergent nozzle. Errors due to trajectory dispersion, burst splitting, and multi-particle signals are discussed.

  15. Comparison of the Trace Elements and Active Components of Lonicera japonica flos and Lonicera flos Using ICP-MS and HPLC-PDA.

    Science.gov (United States)

    Zhao, Yueran; Dou, Deqiang; Guo, Yueqiu; Qi, Yue; Li, Jun; Jia, Dong

    2018-06-01

    Thirteen trace elements and active constituents of 40 batches of Lonicera japonica flos and Lonicera flos were comparatively studied using inductively coupled plasma mass-spectrometry (ICP-MS) and high-performance liquid chromatography-photodiode array (HPLC-PDA). The trace elements were 24 Mg, 52 Cr, 55 Mn, 57 Fe, 60 Ni, 63 Cu, 66 Zn, 75 As, 82 Se, 98 Mo, 114 Cd, 202 Hg, and 208 Pb, and the active compounds were chlorogenic acid, 3,5-O-dicaffeoylquinc acid, 4,5-O-dicaffeoylquinc acid, luteolin-7-O-glucoside, and 4-O-caffeoylquinic acid. The data of 18 variables were statistically processed using principal component analysis (PCA) and discriminate analysis (DA) to classify L. japonica flos and L. flos. The validated method was developed to divide the 40 samples into two groups based on the PCA in terms of 18 variables. Furthermore, the species of Lonicera was better discriminated by using DA with 12 variables. These results suggest that the method and statistical analysis of the contents of trace elements and chemical components can classify the L. japonica flos and L. flos using 12 variables, such as 3,5-O-dicaffeoylquincacid, luteolin-7-O-glucoside, Cd, Mn, Hg, Pb, Ni, 4-O-caffeoyl-quinic acid, 4,5-O-dicaffeoylquinc acid, Fe, Mg, and Cr.

  16. Errors analysis in the evaluation of particle concentration by PDA on a turbulent two-phase jet: application for cross section and transit time methods

    Energy Technology Data Exchange (ETDEWEB)

    Calvo, Esteban; Garcia, Juan A.; Garcia, Ignacio; Aisa, Luis A. [University of Zaragoza, Area de Mecanica de Fluidos, Centro Politecnico Superior, Zaragoza (Spain)

    2009-09-15

    Phase-Doppler anemometry (PDA) is a powerful tool for two-phase flow measurements and testing. Particle concentration and mass flux can also be evaluated using the raw particle data supplied by this technique. The calculation starts from each particle velocity, diameter, transit time data, and the total measurement time. There are two main evaluation strategies. The first one uses the probe volume effective cross section, and it is usually simplified assuming that particles follow quasi one-directional trajectories. In the text, it will be called the cross section method. The second one includes a set of methods which will be denoted as ''Generalized Integral Methods'' (GIM). Concentration algorithms such as the transit time method (TTM) and the integral volume method (IVM) are particular cases of the GIM. In any case, a previous calibration of the measurement volume geometry is necessary to apply the referred concentration evaluation methods. In this study, concentrations and mass fluxes both evaluated by the cross-section method and the TTM are compared. Experimental data are obtained from a particle-laden jet generated by a convergent nozzle. Errors due to trajectory dispersion, burst splitting, and multi-particle signals are discussed. (orig.)

  17. Phytochemical screening by LC-MS and LC-PDA of ethanolic extracts from the fruits of Kigelia africana (Lam.) Benth.

    Science.gov (United States)

    Costa, Rosaria; Albergamo, Ambrogina; Pellizzeri, Vito; Dugo, Giacomo

    2017-06-01

    Kigelia africana is a tree native to Africa, with a local employment in numerous fields, ranging from traditional medicine to cosmetics and religious rituals. Parts of the plant generally used are stem bark, fruits, roots and leaves. The fruits, which have a singular 'sausage' shape, are widely exploited by local folk, in particular for applications/products involving genito-urinary apparatus of both human genders. The scope of this work was to make a consistent chemical investigation on this plant species, in order to clarify and increase the information at present available in literature. To this aim, ethanolic extracts of K. africana fruits were analysed by high-performance liquid chromatography with photodiode array (HPLC-PDA) and electrospray-mass spectrometry (HPLC-ESI-MS) detection, revealing the presence of polyphenols and iridoids. The two detection systems used along with standard co-injection and comparison with previous reports, led to the identification and quantification of six phenolic compounds and three iridoids.

  18. Digital multilayer tomography

    International Nuclear Information System (INIS)

    Dueber, C.; Klose, K.J.; Thelen, M.

    1991-01-01

    With digital multilayer tomography a sequence of projection images is recorded by an image intensifier television system and stored as digital data during a linear run of a layer sequence. Using this data record, tomograms of the examined body region can be computed for any layer thickness by shifts and superimposition of the single projections later at a digital workstation. The qualities of digital and conventional tomograms are basically comparable. A drawback of digital tomography is its lower local resolution (512 x 512 image matrix), advantages are a lower radiation exposure, a shorter patient examination time, and the facilities of digital image processing (later processing, archive setup, transmission). (orig.) [de

  19. Experience with digital mammography

    Directory of Open Access Journals (Sweden)

    G. P. Korzhenkova

    2011-01-01

    Full Text Available The use of digital techniques in mammography has become a last step for completing the process of digitization in diagnostic imaging. It is assumed that such a spatial decision will be required for digital mammography, as well as for high-resolution intensifying screen-film systems used in conventional mammography and that the digital techniques will be limited by the digitizer pixel size on detecting minor structures, such as microcalcifications. The introduction of digital technologies in mammography involves a tight control over an image and assures its high quality.

  20. Logic of the digital

    CERN Document Server

    Evens, Aden

    2015-01-01

    Building a foundational understanding of the digital, Logic of the Digital reveals a unique digital ontology. Beginning from formal and technical characteristics, especially the binary code at the core of all digital technologies, Aden Evens traces the pathways along which the digital domain of abstract logic encounters the material, human world. How does a code using only 0s and 1s give rise to the vast range of applications and information that constitutes a great and growing portion of our world? Evens' analysis shows how any encounter between the actual and the digital must cross an ontolo

  1. Unlocking investment in cities: ELENA-EIB technical assistance facility

    International Nuclear Information System (INIS)

    Cicmanova, Jana; Garabetian, Thomas

    2015-06-01

    Energy Cities prepared a review of projects undertaken in the cities of Paris, Malmoe (in association with Lund and Helsingborg), Barcelona, Bristol and Brussels-Capital that received support from the ELENA-EIB facility. The aim of this study is to identify the ways in which technical assistance programs such as ELENA-EIB can help unlock investment in cities. The projects we reviewed (developed by Energy Cities' members) cover a wide array of sectors, from public building refurbishment to public transport or renewable energy production. These five projects illustrate how cities can focus on developing capacity in a long-term perspective, looking at the expected benefits of an investment or a support mechanism beyond that of the project itself. Overall, we found that project development assistance mechanisms such as ELENA can be beneficial to trigger investment for climate action in cities. Cities maximise the benefits of such a program by looking at how their climate-protection actions can generate benefits for the citizens, or how to systematically integrate climate action in other investment projects. Project development assistance (PDA) affects cities by allowing them to develop a new vision of the way they prepare an investment program. The search of synergies and the override of silo mentalities were a core element in the projects we reviewed. Indeed, the support provided by the European Union through ELENA-EIB is used by the local authorities to develop a transversal approach to climate action. The grant provided for PDA and the requirements of the ELENA-EIB facility represent an opportunity for local authorities to set up a new strategy regarding energy efficiency and renewable energy actions. It can be the necessary push for cities and local authorities to change the way they plan their investments, and develop projects to achieve their climate objectives. Besides, the grant is used for building long-term capacity in the development of investment programs

  2. Successful replantation in ten-digit amputation.

    Science.gov (United States)

    Kantarci, Umit; Cepel, Selim; Buldu, Halil

    2010-01-01

    Amputations involving ten digits are very rare because of different lengths of the digits. A 34-year-old man working in a printing house presented one hour after guillotine amputation involving all ten digits. Surgery was initiated 80 minutes after admission and took seven hours. Under axillary anesthesia, the operation was performed by two teams each consisting of two microsurgeons and two assistants. Replantation was completed without the use of any skin graft or flap. Fingertip examination showed poor arterial circulation in the second, third, and fourth digits of the left hand after 24 hours of replantation and surgical exploration was performed, during which anastomosis of the ulnar digital artery of the second digit was re-established and a Y-shaped vein graft was placed at the level of the third web to restore revascularization of the third and fourth digits. However, these interventions did not prevent the development of necrosis in the distal segment of the fourth digit which resulted in dry gangrene that required amputation. After 38 months of replantation, radiographic examination showed complete union in all fingers without malunion or damage to the joint surface and about 8 degrees of medial angulation in the proximal phalanx of the fourth digit of the right hand. The patient did not have difficulty in performing daily activities and had a considerably good pinching. Losses of active range of motion of the metacarpophalangeal and interphalangeal joints were within the rage of 10 to 30 degrees in both hands. In the assessment of sensation, static and dynamic two-point discrimination test results were 6.1 mm and 4.0 mm, respectively.

  3. Digital Storytelling – Special issue

    Directory of Open Access Journals (Sweden)

    Yngve Nordkvelle

    2010-11-01

    Wiesinger et al. We think, however, that an exploration of a more multimedial approach to dissemination of research in the field is needed. With this in mind, we believe that “Seminar.net”, unhampered by many of the limits of the medium of paper, offers an opportunity to express a richer account of the field. We have encouraged the authors to provide presentations that use digital stories as examples, demonstrations, and expositions, while maintaining certain traditional academic elements, such as an abstract and references. We hope the readers will appreciate the variety of genres that support the ordinary textual information of this journal. All contributions have been peer-reviewed by independent reviewers, who are selected among members of our editorial board, and an expert panel. The less conventional papers have been selected to fit in with our section of “Practical papers”. We consider these papers of high practical merit. We thank Joe Lambert of the Center for Digital Storytelling, professor Theo Hug of University of Innsbruck, and professor Knut Lundby, University of Oslo who have acted as an advisory board to the editors for this special issue. They have provided us with access to their networks, assisted in attracting good reviewers and responded to our practical and principal questions along the way to publishing.Teaching and learning with Digital StorytellingMonica Nilsson, at the University of Stockholm, discusses digital storytelling in this article. A digital story is defined as a multimodal narrative text comprising  pictures, music, speech, sound and script.  In the article she describes and analyzes a nine year old boy´s digital stories and argues that new media, here as digital storytelling, has the potential to play a significant role in the development of both literacy and creativity.Grete Jamissen and Goro Skou work at the University College of Oslo. In their article, “ Poetic reflection through digital storytelling – a methodology to

  4. Analysis of Bearing Capacity Pile Foundation with Using Capwap Software for Testing Pile Driving Analyzer (pda) at Fasfel Development Project Parlimbungan Ketek Sikara-Kara Mandailing Natal District (north Sumatera)

    Science.gov (United States)

    Oberlyn Simanjuntak, Johan; Suita, Diana

    2017-12-01

    Pile foundation is one type deep foundation that serves to distribute the load of hard soil structure loading which has a high bearing capacity that is located deep enough inside the soil. To determine the bearing capacity of the pile and at the same time control the Calendring results, the Pile Driving Analyzer (PDA) test at 8 pile sections from the 84 point piling section (10% of the number sections), the results were analyzed by CAPWAP SOFTWARE, and the highest bearing capacity of Ru 177 ton and the lowest bearing capacity of 111 tons, is bigger than the plan load which load plans that is 60,9 tons. Finally the PDA safe is bearing bearing capacity of the load planning.

  5. Coastal California Digital Imagery

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This digital ortho-imagery dataset is a survey of coastal California. The project area consists of approximately 3774 square miles. The project design of the digital...

  6. Digital rectal exam

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007069.htm Digital rectal exam To use the sharing features on this page, please enable JavaScript. A digital rectal exam is an examination of the lower ...

  7. Evaluating the intra- and interobserver reliability of three-dimensional ultrasound and power Doppler angiography (3D-PDA) for assessment of placental volume and vascularity in the second trimester of pregnancy.

    Science.gov (United States)

    Jones, Nia W; Raine-Fenning, Nick J; Mousa, Hatem A; Bradley, Eileen; Bugg, George J

    2011-03-01

    Three-dimensional (3-D) power Doppler angiography (3-D-PDA) allows visualisation of Doppler signals within the placenta and their quantification is possible by the generation of vascular indices by the 4-D View software programme. This study aimed to investigate intra- and interobserver reproducibility of 3-D-PDA analysis of stored datasets at varying gestations with the ultimate goal being to develop a tool for predicting placental dysfunction. Women with an uncomplicated, viable singleton pregnancy were scanned at 12, 16 or 20 weeks gestational age groups. 3-D-PDA datasets acquired of the whole placenta were analysed using the VOCAL software processing tool. Each volume was analysed by three observers twice in the A plane. Intra- and interobserver reliability was assessed by intraclass correlation coefficients (ICCs) and Bland Altman plots. At each gestational age group, 20 low risk women were scanned resulting in 60 datasets in total. The ICC demonstrated a high level of measurement reliability at each gestation with intraobserver values >0.90 and interobserver values of >0.6 for the vascular indices. Bland Altman plots also showed high levels of agreement. Systematic bias was seen at 20 weeks in the vascular indices obtained by different observers. This study demonstrates that 3-D-PDA data can be measured reliably by different observers from stored datasets up to 18 weeks gestation. Measurements become less reliable as gestation advances with bias between observers evident at 20 weeks. Copyright © 2011 World Federation for Ultrasound in Medicine & Biology. Published by Elsevier Inc. All rights reserved.

  8. Digital dannelse til gymnasieeleverne

    DEFF Research Database (Denmark)

    Kaarsted, Thomas; Holch Andersen, Knud

    2012-01-01

    Søsætningen af en ny tænketank skal udstikke nye digital retningslinjer for gymnasiekolerne. Baggrunden er en erkendelse af, at it-infrastruktur og digital teknologi ikke gør de alene.......Søsætningen af en ny tænketank skal udstikke nye digital retningslinjer for gymnasiekolerne. Baggrunden er en erkendelse af, at it-infrastruktur og digital teknologi ikke gør de alene....

  9. Basic digital signal processing

    CERN Document Server

    Lockhart, Gordon B

    1985-01-01

    Basic Digital Signal Processing describes the principles of digital signal processing and experiments with BASIC programs involving the fast Fourier theorem (FFT). The book reviews the fundamentals of the BASIC program, continuous and discrete time signals including analog signals, Fourier analysis, discrete Fourier transform, signal energy, power. The text also explains digital signal processing involving digital filters, linear time-variant systems, discrete time unit impulse, discrete-time convolution, and the alternative structure for second order infinite impulse response (IIR) sections.

  10. Digital asset management.

    Science.gov (United States)

    Humphrey, Clinton D; Tollefson, Travis T; Kriet, J David

    2010-05-01

    Facial plastic surgeons are accumulating massive digital image databases with the evolution of photodocumentation and widespread adoption of digital photography. Managing and maximizing the utility of these vast data repositories, or digital asset management (DAM), is a persistent challenge. Developing a DAM workflow that incorporates a file naming algorithm and metadata assignment will increase the utility of a surgeon's digital images. Copyright 2010 Elsevier Inc. All rights reserved.

  11. Digital Inkjet Textile Printing

    OpenAIRE

    Wang, Meichun

    2017-01-01

    Digital inkjet textile printing is an emerging technology developed with the rise of the digital world. It offers a possibility to print high-resolution images with unlimited color selection on fabrics. Digital inkjet printing brings a revolutionary chance for the textile printing industry. The history of textile printing shows the law how new technology replaces the traditional way of printing. This indicates the future of digital inkjet textile printing is relatively positive. Differen...

  12. Digital X-ray Imaging in Dentistry

    International Nuclear Information System (INIS)

    Kim, Eun Kyung

    1999-01-01

    In dentistry, Radio Visio Graphy was introduced as a first electronic dental x-ray imaging modality in 1989. Thereafter, many types of direct digital radiographic systems have been produced in the last decade. They are based either on charge-coupled device (CCD) or on storage phosphor technology. In addition, new types of digital radiographic system using amorphous selenium, image intensifier etc. are under development. Advantages of digital radiographic system are elimination of chemical processing, reduction in radiation dose, image processing, computer storage, electronic transfer of images and so on. Image processing includes image enhancement, image reconstruction, digital subtraction, etc. Especially digital subtraction and reconstruction can be applied in many aspects of clinical practice and research. Electronic transfer of images enables filmless dental hospital and teleradiology/teledentistry system. Since the first image management and communications system (IMACS) for dentomaxillofacial radiology was reported in 1992, IMACS in dental hospital has been increasing. Meanwhile, researches about computer-assisted diagnosis, such as structural analysis of bone trabecular patterns of mandible, feature extraction, automated identification of normal landmarks on cephalometric radiograph and automated image analysis for caries or periodontitis, have been performed actively in the last decade. Further developments in digital radiographic imaging modalities, image transmission system, imaging processing and automated analysis software will change the traditional clinical dental practice in the 21st century.

  13. Digital X-ray Imaging in Dentistry

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Eun Kyung [Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Dankook University, Yongin (Korea, Republic of)

    1999-08-15

    In dentistry, Radio Visio Graphy was introduced as a first electronic dental x-ray imaging modality in 1989. Thereafter, many types of direct digital radiographic systems have been produced in the last decade. They are based either on charge-coupled device (CCD) or on storage phosphor technology. In addition, new types of digital radiographic system using amorphous selenium, image intensifier etc. are under development. Advantages of digital radiographic system are elimination of chemical processing, reduction in radiation dose, image processing, computer storage, electronic transfer of images and so on. Image processing includes image enhancement, image reconstruction, digital subtraction, etc. Especially digital subtraction and reconstruction can be applied in many aspects of clinical practice and research. Electronic transfer of images enables filmless dental hospital and teleradiology/teledentistry system. Since the first image management and communications system (IMACS) for dentomaxillofacial radiology was reported in 1992, IMACS in dental hospital has been increasing. Meanwhile, researches about computer-assisted diagnosis, such as structural analysis of bone trabecular patterns of mandible, feature extraction, automated identification of normal landmarks on cephalometric radiograph and automated image analysis for caries or periodontitis, have been performed actively in the last decade. Further developments in digital radiographic imaging modalities, image transmission system, imaging processing and automated analysis software will change the traditional clinical dental practice in the 21st century.

  14. Digital Language Death

    Science.gov (United States)

    Kornai, András

    2013-01-01

    Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off caused by the digital divide. PMID:24167559

  15. Digital language death.

    Directory of Open Access Journals (Sweden)

    András Kornai

    Full Text Available Of the approximately 7,000 languages spoken today, some 2,500 are generally considered endangered. Here we argue that this consensus figure vastly underestimates the danger of digital language death, in that less than 5% of all languages can still ascend to the digital realm. We present evidence of a massive die-off caused by the digital divide.

  16. Digital Imaging. Chapter 16

    Energy Technology Data Exchange (ETDEWEB)

    Clunie, D. [CoreLab Partners, Princeton (United States)

    2014-09-15

    The original means of recording X ray images was a photographic plate. Nowadays, all medical imaging modalities provide for digital acquisition, though globally, the use of radiographic film is still widespread. Many modalities are fundamentally digital in that they require image reconstruction from quantified digital signals, such as computed tomography (CT) and magnetic resonance imaging (MRI)

  17. Preparing collections for digitization

    CERN Document Server

    Bulow, Anna E

    2010-01-01

    Most libraries, archives and museums are confronting the challenges of providing digital access to their collections. This guide offers guidance covering the end-to-end process of digitizing collections, from selecting records for digitization to choosing suppliers and equipment and dealing with documents that present individual problems.

  18. Digital voltage discriminator

    International Nuclear Information System (INIS)

    Zhou Zhicheng

    1992-01-01

    A digital voltage discriminator is described, which is synthesized by digital comparator and ADC. The threshold is program controllable with high stability. Digital region of confusion is approximately equal to 1.5 LSB. This discriminator has a single channel analyzer function model with channel width of 1.5 LSB

  19. Playtesting the Digital Playground

    DEFF Research Database (Denmark)

    Majgaard, G.; Jessen, Carsten

    2009-01-01

    Being able to be absorbed in play in the digital playground is motivating for children who are used digital computer games. The children can play and exercise outdoors while using the same literacy as in indoor digital games. This paper presents a new playground product where an outdoor playgroun...

  20. High Performance Proactive Digital Forensics

    International Nuclear Information System (INIS)

    Alharbi, Soltan; Traore, Issa; Moa, Belaid; Weber-Jahnke, Jens

    2012-01-01

    With the increase in the number of digital crimes and in their sophistication, High Performance Computing (HPC) is becoming a must in Digital Forensics (DF). According to the FBI annual report, the size of data processed during the 2010 fiscal year reached 3,086 TB (compared to 2,334 TB in 2009) and the number of agencies that requested Regional Computer Forensics Laboratory assistance increasing from 689 in 2009 to 722 in 2010. Since most investigation tools are both I/O and CPU bound, the next-generation DF tools are required to be distributed and offer HPC capabilities. The need for HPC is even more evident in investigating crimes on clouds or when proactive DF analysis and on-site investigation, requiring semi-real time processing, are performed. Although overcoming the performance challenge is a major goal in DF, as far as we know, there is almost no research on HPC-DF except for few papers. As such, in this work, we extend our work on the need of a proactive system and present a high performance automated proactive digital forensic system. The most expensive phase of the system, namely proactive analysis and detection, uses a parallel extension of the iterative z algorithm. It also implements new parallel information-based outlier detection algorithms to proactively and forensically handle suspicious activities. To analyse a large number of targets and events and continuously do so (to capture the dynamics of the system), we rely on a multi-resolution approach to explore the digital forensic space. Data set from the Honeynet Forensic Challenge in 2001 is used to evaluate the system from DF and HPC perspectives.

  1. From Computer Assisted Language Learning (CALL) to Mobile Assisted Language Use (MALU)

    Science.gov (United States)

    Jarvis, Huw; Achilleos, Marianna

    2013-01-01

    This article begins by critiquing the long-established acronym CALL (Computer Assisted Language Learning). We then go on to report on a small-scale study which examines how student non-native speakers of English use a range of digital devices beyond the classroom in both their first (L1) and second (L2) languages. We look also at the extent to…

  2. Tc-labeling of Peptidomimetic Antagonist to Selectively Target alpha(v)beta(3) Receptor-Positive Tumor: Comparison of PDA and EDDA as co-Ligands.

    Science.gov (United States)

    Shin, In Soo; Maeng, Jin Soo; Jang, Beom-Su; You, Eric; Cheng, Kenneth; Li, King C P; Wood, Bradford; Carrasquillo, Jorge A; Danthi, S Narasimhan; Paik, Chang H

    2010-01-01

    OBJECTIVES: The aim of this research was to synthesize radiolabeled peptidomimetic integrin alpha(v)beta(3) antagonist with (99m)Tc for rapid targeting of integrin alpha(v)beta(3) receptors in tumor to produce a high tumor to background ratio. METHODS: The amino terminus of 4-[2-(3,4,5,6-tetra-hydropyrimidin-2-ylamino)-ethyloxy]benzoyl-2-(S)-[N-(3-amino-neopenta-1-carbamyl)]-aminoethylsulfonyl-amino-beta-alanine hydrochloride (IAC) was conjugated with N-hydroxysuccinimide ester of HYNIC and labeled with (99m)Tc using tricine with either 1,5-pyridinedicarboxylic acid (PDA) or ethylenediamine-N,N'-diacetic acid (EDDA) as the co-ligand. The products, (99m)Tc EDDA(2)/HYNIC-IAC (P1) and (99m)Tc PDA (tricin)/HYNIC-IAC (P2) were subjected to in vitro serum stability, receptor-binding, biodistribution and imaging studies. RESULTS: P1 and P2 were synthesized with an overall yield of >80%. P1 was slightly more stable than P2 when incubated in serum at 37 degrees C for 18 hrs (84 vs 77% intact). The In vitro receptor-binding of P1 was higher than that of P2 (78.02 +/- 13.48 vs 51.05 +/- 14.05%) when incubated with alpha(v)beta(3) at a molar excess (0.8 muM). This receptor binding was completely blocked by a molar excess of an unlabeled peptidomimetic antagonist. Their differences shown in serum stability and the receptor-binding appeared to be related to their biological behaviors in tumor uptake and retention; the 1 h tumor uptakes of P1 and P2 were 3.17+/-0.52 and 2.13+/-0.17 % ID/g, respectively. P1 was retained in the tumor longer than P2. P1 was excreted primarily through the renal system whereas P2 complex was excreted equally via both renal and hepatobiliary systems. Thus, P1 was retained in the whole-body with 27.25 +/- 3.67% ID at 4 h whereas 54.04 +/- 3.57% ID of P2 remained in the whole-body at 4 h. This higher whole-body retention of P2 appeared to be resulted from a higher amount of radioactivity retained in liver and intestine. These findings were supported by

  3. Ageing and digital games

    DEFF Research Database (Denmark)

    Iversen, Sara Mosberg

    Digital games are still to a great degree considered a medium mainly for young boys. However, available statistics on Western media use show that this is far from the case. Increasingly, people of all ages and genders play digital games, also older adults in their early 60s and beyond. The aim...... of the book is to examine, analyse and discuss: 1) What older adults do with digital games and what meanings the use of digital games take on in the everyday life of older adults; 2) How older adults are perceived by society in relation to digital games; 3) How play and games can be used both...

  4. Digital Living at Home

    DEFF Research Database (Denmark)

    Andersen, Pernille Viktoria Kathja; Christiansen, Ellen Tove

    2013-01-01

    of these user voices has directed us towards a ‘home-keeping’ design discourse, which opens new horizons for design of digital home control systems by allowing users to perform as self-determined controllers and groomers of their habitat. The paper concludes by outlining the implications of a ‘home......Does living with digital technology inevitably lead to digital living? Users talking about a digital home control system, they have had in their homes for eight years, indicate that there is more to living with digital technology than a functional-operational grip on regulation. Our analysis......-keeping’ design discourse....

  5. BabyCare: apoio à decisão na atenção primária materno-infantil com computadores de mão BabyCare: decision support system for primary child care using personal digital assistant

    Directory of Open Access Journals (Sweden)

    Carmen Lúcia de Bartolo Costa

    2010-10-01

    Full Text Available O objetivo desta pesquisa foi desenvolver um instrumento digital - aqui denominado Sistema BabyCare - para coleta, armazenamento e apoio à decisão dos profissionais de saúde e demais envolvidos na assistência primária infantil em comunidades carentes. Esse sistema baseia-se em tecnologias de dispositivos móveis para utilização local em unidades básicas de saúde em comunidades carentes, assistidos ou não pelo Programa/Estratégia Saúde da Família (PSF, organizações não governamentais, ambulatórios e hospitais. Utilizou-se Java como linguagem de programação. Foram realizadas avaliações sobre o uso do sistema na cidade de São Paulo, envolvendo 62 usuários com diferentes formações, incluindo voluntários da Pastoral da Criança e do PSF. Os questionários aplicados resultam em alto índice de aceitação geral (98,3%; treinamento in loco considerado adequado (91,9%; percepção na melhoria na rotina e na redução de tempo da consulta (100,0% e na redução no volume de documentos (96,7%. Conclusão: o protótipo apresentou-se robusto e eficiente para uso em comunidades carentes com infraestrutura precária de informática e telecomunicação.The purpose of this work was to develop a digital device - referred as BabyCare System - for the collection, storage, and decision support for healthcare professionals and other concerned people, in order to assist patients in primary child care in deprived communities. This system is based on handheld device technologies to be used locally in basic healthcare units in deprived communities, whether assisted or not by the Family Health Program/Strategy (PSF, as well as in ambulatory facilities and hospitals. Java was used as programming language. Evaluations have been conducted regarding 62 users at São Paulo city including volunteers from the Pastoral da Criança, an ecumenical institution for children. The applied questionnaires resulted in a high level of general acceptance (98

  6. UHPLC-PDA-ESI-TOF/MS metabolic profiling of Arctostaphylos pungens and Arctostaphylos uva-ursi. A comparative study of phenolic compounds from leaf methanolic extracts.

    Science.gov (United States)

    Panusa, Alessia; Petrucci, Rita; Marrosu, Giancarlo; Multari, Giuseppina; Gallo, Francesca Romana

    2015-07-01

    The aim of this study was to get a rapid metabolic fingerprinting and to gain insight into the metabolic profiling of Arctostaphylos pungens H. B. K., a plant morphologically similar to Arctostaphylos uva-ursi (L.) Spreng. (bearberry) but with a lower arbutin (Arb) content. According to the European Pharmacopoeia the Arb content in the dried leaf of A. uva-ursi (L.) Spreng. must be at least 7% (wt/wt) but other species, like A. pungens, are unintentionally or fraudulently marketed instead of it. Therefore, methanolic leaf extracts of nine A. uva-ursi and six A. pungens samples labeled and marketed as "bearberry leaf" have been analyzed. A five-minute gradient with a UHPLC-PDA-ESI-TOF/MS on an Acquity BEH C18 (50×2.1 mm i.d.) 1.7 μm analytical column has been used for the purpose. A comprehensive assignment of secondary metabolites has been carried out in a comparative study of the two species. Among twenty-nine standards of natural compounds analyzed, fourteen have been identified, while other fifty-five metabolites have been tentatively assigned. Moreover, differences in both metabolic fingerprinting and profiling have been evidenced by statistical multivariate analysis. Specifically, main variations have been observed in the relative content for Arb, as expected, and for some galloyl derivative like tetra- and pentagalloylglucose more abundant in A. uva-ursi than in A. pungens. Furthermore, differences in flavonols profile, especially in myricetin and quercetin glycosilated derivatives, were observed. Based on principal component analysis myricetrin, together with a galloyl arbutin isomer and a disaccharide are herein proposed as distinctive metabolites for A. pungens. Copyright © 2015 Elsevier Ltd. All rights reserved.

  7. Application of Response Surface Methodology for Optimisation of Simultaneous UHPLC-PDA Determination of Oleanolic and Ursolic Acids and Standardisation of Ericaceae Medicinal Plants

    Directory of Open Access Journals (Sweden)

    Aleksandra Owczarek

    2016-08-01

    Full Text Available A fast and sensitive ultra-high performance liquid chromatography-photodiode array (UHPLC-PDA method for simultaneous quantification of oleanolic acid (OA and ursolic acid (UA in plant materials was developed. A central composite design combined with a response surface methodology was utilized to establish optimal separation conditions. The final separation was accomplished on a Zorbax Eclipse XDB-C18 column (1.8 μm, 100 mm × 3 mm I.D., Agilent, Santa Clara, CA, USA using a mixture 90:10 (v/v of methanol and 1% (w/v aqueous orthophosporic acid as a mobile phase at a flow rate of 0.44 mL/min and temperature of 18 °C. The analysis was completed in 6.2 min with satisfactory resolution of 1.5 between the target analytes. The developed method proved to be precise (relative standard deviations below 3.2%, accurate (recoveries in the range of 95.27%–98.60%, and sensitive (limits of detection (LODs in the range of 0.047–0.051 mg/mL. The method was then successfully applied to evaluate OA and UA content in real samples of selected Ericaceae plant materials (leaves of Arctostaphylos uva ursi, Vaccinium myrtillus, Vaccinium vitis idaea, Gaultheria procumbens. The content of OA and UA in investigated samples varied in the range of 0.74–4.47 mg/g dry weight (dw and 1.30–18.61 mg/g dw, respectively.

  8. Digital Image Quantitative Evaluations for Low Cost Film Digitizers Height Determination

    International Nuclear Information System (INIS)

    Khairul Anuar Mohd Salleh; Arshad Yassin; Ahmad Nasir Yusof; Noorhazleena Azaman

    2016-01-01

    Non Destructive Testing (NDT) technology contributes significant improvement to the quality of industrial products, and the integrity of equipment and plants. Introduction of powerful computers and reliable imaging technology has had significant impact on the traditional nuclear based NDT technology. Demand for faster, reliable, low cost, and flexible technology is rapidly increased. With the growing demand for more efficient digital archiving, digital image analysis, and reporting results with a low cost technology, one cannot deny the importance of having another cheaper solution. This project will apply fundamental principle of image digitization to be used in building up a low cost film digitization solution. The height of the film digitization was carefully determined by examining each digital images produced. Three (3) repetitive quantitative evaluations (Modulation Transfer Function [MTF], Characteristic Transfer Curve [CTC], and Contrast to Noise Ratio [CNR]) were performed at different condition to assist with the determination of the low cost film digitizers height. All 3 evaluations were successfully applied and the most appropriate height was successfully determined. (author)

  9. Digital positron annihilation spectrometer

    International Nuclear Information System (INIS)

    Cheng Bin; Weng Huimin; Han Rongdian; Ye Bangjiao

    2010-01-01

    With the high speed development of digital signal process, the technique of the digitization and processing of signals was applied in the domain of a broad class of nuclear technique. The development of digital positron lifetime spectrometer (DPLS) is more promising than the conventional positron lifetime spectrometer equipped with nuclear instrument modules. And digital lifetime spectrometer has many advantages, such as low noise, long term stability, flexible online or offline digital processing, simple setup, low expense, easy to setting, and more physical information. Digital constant fraction discrimination is for timing. And a new method of optimizing energy windows setting for digital positron lifetime spectrometer is also developed employing the simulated annealing for the convenient use. The time resolution is 220ps and the count rate is 200cps. (authors)

  10. Empirical Study on the Effect of Digital Game-Based Instruction on Students' Learning Motivation and Achievement

    Science.gov (United States)

    Chen, Yen-Chun

    2017-01-01

    As pupils are largely increased the opportunities to contact digital games, the effect of digital games has been broadly discussed and studied. Digital games no longer play the function of entertainment, but could assist students in more active learning and deeper and broader learning, when being applied to instruction. It is limited to learn in…

  11. Digital Banking: Risks of Financial Digitalization

    Directory of Open Access Journals (Sweden)

    Kornіvska Valerіa O.

    2017-09-01

    Full Text Available The paper demonstrates the results of the research into development of the digital economy in the global financial space, shows the contradictions of these processes in the context of the growth of financial inclusion of households, identifies the risks of active introduction of digital banking in poor countries of the world. The characteristics of the processes of growth of the influence of banking institutions on the operational activity and daily life of households are given, and it is proved that under conditions of digital banking, without having any other alternative ways of economic activity in terms of money circulation than non-cash turnover, clients are forced to agree to unlimited presence of financial operators in social systems. It is substantiated that in Ukraine the global risk of digitalization of the society is gradually developing as a result of the creation of unified information systems for the control of global financial flows.

  12. Digital rights management for digital cinema

    Science.gov (United States)

    Kirovski, Darko; Peinado, Marcus; Petitcolas, Fabien A. P.

    2001-12-01

    There is a wide consensus among the feature film production studios that the Internet era brings a new paradigm for film distribution to cinemas worldwide. The benefits of digital cinema to both producers and cinemas are numerous: significantly lower distribution and maintenance costs, immediate access to film libraries, higher presentation quality, and strong potential for developing new business models. Despite these advantages, the studios are still reluctant to jump into the digital age. The main showstopper for digital cinema is the danger of widespread piracy. Piracy already costs Hollywood an estimated two billion dollars annually and digital cinema without proper copyright enforcement could increase this number. In this paper, we present a copyright management system that aims at providing the set of necessary security tools: standard cryptographic primitives and copyright protection mechanisms that enable a reliable and secure feature film delivery system.

  13. Digital Collections, Digital Libraries and the Digitization of Cultural Heritage Information.

    Science.gov (United States)

    Lynch, Clifford

    2002-01-01

    Discusses the development of digital collections and digital libraries. Topics include digitization of cultural heritage information; broadband issues; lack of compelling content; training issues; types of materials being digitized; sustainability; digital preservation; infrastructure; digital images; data mining; and future possibilities for…

  14. Comparison of posterolateral thoracotomy and video-assisted thoracoscopic clipping for the treatment of patent ductus arteriosus in neonates and infants.

    Science.gov (United States)

    Chen, Haiyu; Weng, Guoxing; Chen, Zhiqun; Wang, Huan; Xie, Qi; Bao, Jiayin; Xiao, Rongdong

    2011-04-01

    This study was designed to compare the long-term clinical outcomes and costs between video-assisted thoracic surgery (VATS) and posterolateral thoracotomy (PT) in neonates and infants. This study enrolled 302 patients with isolated patent ductus arteriosus (PDA) from January 2002 to 2007 and followed them up until April 2010. A total of 134 patients underwent total VATS (VATS group), and 168 underwent PDA closure through PT (PT group). The two groups were compared according to clinical outcomes and costs. The demographics and preoperative clinical characteristics of the patients were similar in the two groups. No cardiac deaths occurred, and the closure rate was 100% successful in both groups. The operating, recovery, and pleural fluid drainage times were significantly shorter in the VATS group than in the PT group. Statistically significant differences in length of incision, postoperative temperature, and acute procedure-related complications were observed between the two groups. The cost was $1,150.3 ± $221.2 for the VATS group and $2415.8 ± $345.2 for the PT group (P ventricular end-diastolic diameter and the pulmonary artery diameter could be restored to normal in the VATS group but not in the PT group. The study confirmed that VATS offers a minimally traumatic, safe, and effective technique for PDA interruption in neonates and infants.

  15. Assisted Vaginal Delivery

    Science.gov (United States)

    ... Education & Events Advocacy For Patients About ACOG Assisted Vaginal Delivery Home For Patients Search FAQs Assisted Vaginal ... Vaginal Delivery FAQ192, February 2016 PDF Format Assisted Vaginal Delivery Labor, Delivery, and Postpartum Care What is ...

  16. Canine assisted reading

    OpenAIRE

    Sever, Jerneja

    2016-01-01

    The diploma thesis presents various aspects of animals included in animal-assisted interventions. In theoretical part, I introduced different possible ways of animal-assisted interventions: animal-assisted therapy, animal-assisted activities and animal-assisted education. Animals became common visitors in educational settings all over the world. I presented positive influences on various aspects of human life, as well limitations when animal-assisted interventions are not possible to perform ...

  17. Digital Simulation in the Geosciences

    Directory of Open Access Journals (Sweden)

    Alexandr A. Lobanov

    2014-09-01

    Full Text Available This article provides an analysis of methods for digital modeling in the area of Earth Sciences. The author illustrates the difference between digital modeling in radio communication and that in the area of Earth Sciences. The article examines the integration aspect of digital models, demonstrates the advantages of digital over analog models, and illustrates that digital models are discrete. The author outlines the characteristics of digital modeling and illustrates the logical structure of digital models.

  18. Digital radiology and ultrasound

    International Nuclear Information System (INIS)

    Todd-Pokropek, A.

    1991-01-01

    With the access to digital methods for handling and processing images in general, many medical imaging methods are becoming more effectively handled digitally. This applies in particular to basically digital techniques such as CT and MR but also now includes Nuclear Medicine (NM), Ultrasound (US) and a variety of radiological procedures such as Digital Subtraction Angiography (DSA) and Fluoroscopy (DF). The access to conventional projection images by stimulatable plates (CR) or by digitization of film makes all of radiology potentially accessible, and the management of such images by a network is the basic aim of Picture Archiving and Communication Systems (PACS). However, it is suggested that in order for such systems to be of greater value, that way in which such images are treated needs to change, that is, digital images can be used to derive additional clinical value by appropriate processing

  19. Digital cine-imaging

    International Nuclear Information System (INIS)

    Masuda, Kazuhiro

    1992-01-01

    Digitization of fluoroscopic images has been developed for the digital cine imaging system as a result of the computer technology, television technology, and popularization of interventional radiology. Present digital cine imaging system is able to offer images similar to cine film because of the higher operatability and better image quality with the development of interventional radiology. As a result, its higher usefulness for catheter diagnosis examination except for interventional radiology was reported, and the possibility of having filmless cine is close to becoming a reality. However several problems have been pointed out, such as spatial resolution, time resolution, storage and exchangeability of data, disconsolidated viewing functions, etc. Anyhow, digital cine imaging system has some unresolved points and lots the needs to be discussed. The tendency of digitization is the passage of the time and we have to promote a study for more useful digital cine imaging system in team medical treatment which centers on the patients. (author)

  20. Theory of Digital Automata

    CERN Document Server

    Borowik, Bohdan; Lahno, Valery; Petrov, Oleksandr

    2013-01-01

    This book serves a dual purpose: firstly to combine the treatment of circuits and digital electronics, and secondly, to establish a strong connection with the contemporary world of digital systems. The need for this approach arises from the observation that introducing digital electronics through a course in traditional circuit analysis is fast becoming obsolete. Our world has gone digital. Automata theory helps with the design of digital circuits such as parts of computers, telephone systems and control systems. A complete perspective is emphasized, because even the most elegant computer architecture will not function without adequate supporting circuits. The focus is on explaining the real-world implementation of complete digital systems. In doing so, the reader is prepared to immediately begin design and implementation work. This work serves as a bridge to take readers from the theoretical world to the everyday design world where solutions must be complete to be successful.

  1. Digital collections and exhibits

    CERN Document Server

    Denzer, Juan

    2015-01-01

    Today's libraries are taking advantage of cutting-edge technologies such as flat panel displays using touch, sound, and hands-free motions to design amazing exhibits using everything from simple computer hardware to advanced technologies such as the Microsoft Kinect. Libraries of all types are striving to add new interactive experiences for their patrons through exciting digital exhibits, both online and off. Digital Collections and Exhibits takes away the mystery of designing stunning digital exhibits to spotlight library trea

  2. The digital computer

    CERN Document Server

    Parton, K C

    2014-01-01

    The Digital Computer focuses on the principles, methodologies, and applications of the digital computer. The publication takes a look at the basic concepts involved in using a digital computer, simple autocode examples, and examples of working advanced design programs. Discussions focus on transformer design synthesis program, machine design analysis program, solution of standard quadratic equations, harmonic analysis, elementary wage calculation, and scientific calculations. The manuscript then examines commercial and automatic programming, how computers work, and the components of a computer

  3. Digital Textile Printing

    OpenAIRE

    Moltchanova, Julia

    2011-01-01

    Rapidly evolving technology of digital printing opens new opportunities on many markets. One of them is the printed fabric market where printing companies as well as clients benefit from new printing methods. This thesis focuses on the digital textile printing technology and its implementation for fabric-on-demand printing service in Finland. The purpose of this project was to study the technology behind digital textile printing, areas of application of this technology, the requirements ...

  4. Digital Sensor Technology

    Energy Technology Data Exchange (ETDEWEB)

    Thomas, Ken D. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Quinn, Edward L. [Technology Resources, Dana Point, CA (United States); Mauck, Jerry L. [Technology Resources, Dana Point, CA (United States); Bockhorst, Richard M. [Technology Resources, Dana Point, CA (United States)

    2015-02-01

    The nuclear industry has been slow to incorporate digital sensor technology into nuclear plant designs due to concerns with digital qualification issues. However, the benefits of digital sensor technology for nuclear plant instrumentation are substantial in terms of accuracy and reliability. This paper, which refers to a final report issued in 2013, demonstrates these benefits in direct comparisons of digital and analog sensor applications. Improved accuracy results from the superior operating characteristics of digital sensors. These include improvements in sensor accuracy and drift and other related parameters which reduce total loop uncertainty and thereby increase safety and operating margins. An example instrument loop uncertainty calculation for a pressure sensor application is presented to illustrate these improvements. This is a side-by-side comparison of the instrument loop uncertainty for both an analog and a digital sensor in the same pressure measurement application. Similarly, improved sensor reliability is illustrated with a sample calculation for determining the probability of failure on demand, an industry standard reliability measure. This looks at equivalent analog and digital temperature sensors to draw the comparison. The results confirm substantial reliability improvement with the digital sensor, due in large part to ability to continuously monitor the health of a digital sensor such that problems can be immediately identified and corrected. This greatly reduces the likelihood of a latent failure condition of the sensor at the time of a design basis event. Notwithstanding the benefits of digital sensors, there are certain qualification issues that are inherent with digital technology and these are described in the report. One major qualification impediment for digital sensor implementation is software common cause failure (SCCF).

  5. Preserving Digital Materials

    CERN Document Server

    Harvey, Ross

    2011-01-01

    This book provides a single-volume introduction to the principles, strategies and practices currently applied by librarians and recordkeeping professionals to the critical issue of preservation of digital information. It incorporates practice from both the recordkeeping and the library communities, taking stock of current knowledge about digital preservation and describing recent and current research, to provide a framework for reflecting on the issues that digital preservation raises in professional practice.

  6. Dakwah di Era Digital

    OpenAIRE

    Budiantoro, Wahyu

    2018-01-01

    These days dakwah is not only interpreted as transformation of a pure religious value, but also transformation of a more relevant value including many aspects in digital era. Digital era is when society succumbed into the flow of information causing cultural shock and difficulties on synthesizing meaning from those scattered information. Dakwah on Digital age must accommodate societal needs which tend to move into a mass society. It results in strategy and more humane and innovative dakwah me...

  7. The Digital Imperative

    OpenAIRE

    Veling, Louise; Murnane, Sinéad; Carcary, Marian; Zlydareva, Olga

    2014-01-01

    The pervasiveness of digital technologies and their potential for reshaping the industry landscape dictates that organizations operating today have little choice but to incorporate digital technologies into their business strategies. Failure to do so will impede the business’s viability, and may ultimately lead to business failure. However, for those organizations that successfully transition to digital business, unprecedented business opportunities exist for value creation and reali...

  8. Digital piracy : theory

    OpenAIRE

    BELLEFLAMME, Paul; PEITZ, Martin

    2010-01-01

    This article reviews recent theoretical contributions on digital piracy. It starts by elaborating on the reasons for intellectual property protection, by reporting a few facts about copyright protection, and by examining reasons to become a digital pirate. Next, it provides an exploration of the consequences of digital piracy, using a base model and several extensions (with consumer sampling, network effects, and indirect appropriation). A closer look at market-structure implications of end-u...

  9. La radio digital

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Cortés S.

    2015-01-01

    Full Text Available La radio digital es un producto de la llamada convergencia digital. Las nuevas tecnologías interconectadas permiten la aparición de nuevos modos de audiencia y la implementación de herramientas versátiles. Habla del problema de los estándares, de la radio satelital, la radio digital terrestre, las radios internacionales, la interactividad.

  10. Easy digital engineering

    International Nuclear Information System (INIS)

    Jin, Dal Bok

    2002-02-01

    This book lists basic of digital engineering, number system and digital code, Boolean algebra and basic logic circuit, simplify of logical expression, combinational circuit, arithmetic circuit, multivibrator circuit, sequential circuit, memory unit of semiconductor and logical element for program, D/A converter and A/D converter, logic element and integrated circuit and logic circuit and micro controller. It has exercises and answers about digital engineering and summary in the end of each chapter.

  11. Debunking the "Digital Native": Beyond Digital Apartheid, towards Digital Democracy

    Science.gov (United States)

    Brown, C.; Czerniewicz, L.

    2010-01-01

    This paper interrogates the currently pervasive discourse of the "net generation" finding the concept of the "digital native" especially problematic, both empirically and conceptually. We draw on a research project of South African higher education students' access to and use of Information and Communication Technologies (ICTs)…

  12. Digital Natives and Digital Divide: Analysing Perspective for Emerging Pedagogy

    Science.gov (United States)

    Onye, Uriel U.; Du, Yunfei

    2016-01-01

    This paper addresses the concepts of digital natives and digital divide from the perspective of the digital outsiders (part of digital natives). It takes a critical look at the implications of available ICT in both developed and underdeveloped countries in the fight against digital divide. The major contribution to literature is by drawing…

  13. Toward a general ontology for digital forensic disciplines.

    Science.gov (United States)

    Karie, Nickson M; Venter, Hein S

    2014-09-01

    Ontologies are widely used in different disciplines as a technique for representing and reasoning about domain knowledge. However, despite the widespread ontology-related research activities and applications in different disciplines, the development of ontologies and ontology research activities is still wanting in digital forensics. This paper therefore presents the case for establishing an ontology for digital forensic disciplines. Such an ontology would enable better categorization of the digital forensic disciplines, as well as assist in the development of methodologies and specifications that can offer direction in different areas of digital forensics. This includes such areas as professional specialization, certifications, development of digital forensic tools, curricula, and educational materials. In addition, the ontology presented in this paper can be used, for example, to better organize the digital forensic domain knowledge and explicitly describe the discipline's semantics in a common way. Finally, this paper is meant to spark discussions and further research on an internationally agreed ontological distinction of the digital forensic disciplines. Digital forensic disciplines ontology is a novel approach toward organizing the digital forensic domain knowledge and constitutes the main contribution of this paper. © 2014 American Academy of Forensic Sciences.

  14. The digital media handbook

    CERN Document Server

    Dewdney, Andrew

    2013-01-01

    The new edition of The Digital Media Handbook presents an essential guide to the historical and theoretical development of digital media, emphasising cultural continuity alongside technological change, and highlighting the emergence of new forms of communication in contemporary networked culture.Andrew Dewdney and Peter Ride present detailed critical commentary and descriptive historical accounts, as well as a series of interviews from a range of digital media practitioners, including producers, developers, curators and artists.The Digital Media Handbook highlights key concerns of today's prac

  15. Digitization of conventional radiographs

    International Nuclear Information System (INIS)

    Wenz, W.; Buitrago-Tellez, C.; Blum, U.; Hauenstein, K.H.; Gufler, H.; Meyer, E.; Ruediger, K.

    1992-01-01

    The diagnostic value of a digitization system for analogue films based on a charge-coupled-device (CCD) scanner with adjustable resolution of 2.5 or 5 lp/mm was assessed. Some 110 skeletal radiographs, 50 contrast studies, including 25 of patients with Crohn's disease, and 70 abdominal plain films before and after successful lithotripsy for renal stones were digitized. Receiver operating characteristic (ROC) studies showed improved detection of cortical and trabecular defects with contrast-optimized digitized films. Edge enhancement algorithms yielded no additional information. Inflammatory lesions of Crohn's disease were detected equally well by conventional films and digitized images. A statistically significant improvement (p [de

  16. Digital security technology simplified.

    Science.gov (United States)

    Scaglione, Bernard J

    2007-01-01

    Digital security technology is making great strides in replacing analog and other traditional security systems including CCTV card access, personal identification and alarm monitoring applications. Like any new technology, the author says, it is important to understand its benefits and limitations before purchasing and installing, to ensure its proper operation and effectiveness. This article is a primer for security directors on how digital technology works. It provides an understanding of the key components which make up the foundation for digital security systems, focusing on three key aspects of the digital security world: the security network, IP cameras and IP recorders.

  17. Digitally-Driven Architecture

    Directory of Open Access Journals (Sweden)

    Henriette Bier

    2014-07-01

    Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisation focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means.In this context, this sixth Footprint issue examines the influence of digital means as pragmatic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

  18. Digitally-Driven Architecture

    Directory of Open Access Journals (Sweden)

    Henriette Bier

    2010-06-01

    Full Text Available The shift from mechanical to digital forces architects to reposition themselves: Architects generate digital information, which can be used not only in designing and fabricating building components but also in embedding behaviours into buildings. This implies that, similar to the way that industrial design and fabrication with its concepts of standardisation and serial production influenced modernist architecture, digital design and fabrication influences contemporary architecture. While standardisa­tion focused on processes of rationalisation of form, mass-customisation as a new paradigm that replaces mass-production, addresses non-standard, complex, and flexible designs. Furthermore, knowledge about the designed object can be encoded in digital data pertaining not just to the geometry of a design but also to its physical or other behaviours within an environment. Digitally-driven architecture implies, therefore, not only digitally-designed and fabricated architecture, it also implies architecture – built form – that can be controlled, actuated, and animated by digital means. In this context, this sixth Footprint issue examines the influence of digital means as prag­matic and conceptual instruments for actuating architecture. The focus is not so much on computer-based systems for the development of architectural designs, but on architecture incorporating digital control, sens­ing, actuating, or other mechanisms that enable buildings to inter­act with their users and surroundings in real time in the real world through physical or sensory change and variation.

  19. Exploring digital professionalism.

    Science.gov (United States)

    Ellaway, Rachel H; Coral, Janet; Topps, David; Topps, Maureen

    2015-01-01

    The widespread use of digital media (both computing devices and the services they access) has blurred the boundaries between our personal and professional lives. Contemporary students are the last to remember a time before the widespread use of the Internet and they will be the first to practice in a largely e-health environment. This article explores concepts of digital professionalism and their place in contemporary medical education, and proposes a series of principles of digital professionalism to guide teaching, learning and practice in the healthcare professions. Despite the many risks and fears surrounding their use, digital media are not an intrinsic threat to medical professionalism. Professionals should maintain the capacity for deliberate, ethical, and accountable practice when using digital media. The authors describe a digital professionalism framework structured around concepts of proficiency, reputation, and responsibility. Digital professionalism can be integrated into medical education using strategies based on awareness, alignment, assessment, and accountability. These principles of digital professionalism provide a way for medical students and medical practitioners to embrace the positive aspects of digital media use while being mindful and deliberate in its use to avoid or minimize any negative consequences.

  20. Radiographic film digitizing devices

    International Nuclear Information System (INIS)

    McFee, W.H.

    1988-01-01

    Until recently, all film digitizing devices for use with teleradiology or picture archiving and communication systems used a video camera to capture an image of the radiograph for subsequent digitization. The development of film digitizers that use a laser beam to scan the film represents a significant advancement in digital technology, resulting in improved image quality compared with video scanners. This paper discusses differences in resolution, efficiency, reliability, and the cost between these two types of devices. The results of a modified receiver operating characteristic comparison study of a video scanner and a laser scanner manufactured by the same company are also discussed

  1. Cognitive Hacking and Digital Government: Digital Identity

    Directory of Open Access Journals (Sweden)

    Paul Thompson

    2004-04-01

    Full Text Available Recently the National Center for Digital Government held a workshop on "The Virtual Citizen: Identity, Autonomy, and Accountability: A Civic Scenario Exploration of the Role of Identity in On-Line. Discussions at the workshop focused on five scenarios for future authentication policies with respect to digital identity. The underlying technologies considered for authentication were: biometrics: cryptography, with a focus on digital signatures; secure processing/computation; and reputation systems. Most discussion at the workshop focused on issues related to authentication of users of digital government, but, as implied by the inclusion of a scenario related to ubiquitous identity theft, there was also discussion of problems related to misinformation, including cognitive hacking. Cognitive hacking refers to a computer or information system attack that relies on changing human users' perceptions and corresponding behaviors in order to succeed. This paper describes cognitive hacking, suggests countermeasures, and discusses the implications of cognitive hacking for identity in digital government. In particular, spoofing of government websites and insider misuse are considered.

  2. Human Grasp Assist Device With Exoskeleton

    Science.gov (United States)

    Bergelin, Bryan J (Inventor); Ihrke, Chris A. (Inventor); Davis, Donald R. (Inventor); Linn, Douglas Martin (Inventor); Bridgwater, Lyndon B. J. (Inventor)

    2014-01-01

    A grasp assist system includes a glove, actuator assembly, and controller. The glove includes a digit, i.e., a finger or thumb, and a force sensor. The sensor measures a grasping force applied to an object by an operator wearing the glove. Phalange rings are positioned with respect to the digit. A flexible tendon is connected at one end to one of the rings and is routed through the remaining rings. An exoskeleton positioned with respect to the digit includes hinged interconnecting members each connected to a corresponding ring, and/or a single piece of slotted material. The actuator assembly is connected to another end of the tendon. The controller calculates a tensile force in response to the measured grasping force, and commands the tensile force from the actuator assembly to thereby pull on the tendon. The exoskeleton offloads some of the tensile force from the operator's finger to the glove.

  3. New techniques in digital holography

    CERN Document Server

    Picart, Pascal

    2015-01-01

    A state of the art presentation of important advances in the field of digital holography, detailing advances related to fundamentals of digital holography, in-line holography applied to fluid mechanics, digital color holography, digital holographic microscopy, infrared holography, special techniques in full field vibrometry and inverse problems in digital holography

  4. [Basic concept in computer assisted surgery].

    Science.gov (United States)

    Merloz, Philippe; Wu, Hao

    2006-03-01

    To investigate application of medical digital imaging systems and computer technologies in orthopedics. The main computer-assisted surgery systems comprise the four following subcategories. (1) A collection and recording process for digital data on each patient, including preoperative images (CT scans, MRI, standard X-rays), intraoperative visualization (fluoroscopy, ultrasound), and intraoperative position and orientation of surgical instruments or bone sections (using 3D localises). Data merging based on the matching of preoperative imaging (CT scans, MRI, standard X-rays) and intraoperative visualization (anatomical landmarks, or bone surfaces digitized intraoperatively via 3D localiser; intraoperative ultrasound images processed for delineation of bone contours). (2) In cases where only intraoperative images are used for computer-assisted surgical navigation, the calibration of the intraoperative imaging system replaces the merged data system, which is then no longer necessary. (3) A system that provides aid in decision-making, so that the surgical approach is planned on basis of multimodal information: the interactive positioning of surgical instruments or bone sections transmitted via pre- or intraoperative images, display of elements to guide surgical navigation (direction, axis, orientation, length and diameter of a surgical instrument, impingement, etc. ). And (4) A system that monitors the surgical procedure, thereby ensuring that the optimal strategy defined at the preoperative stage is taken into account. It is possible that computer-assisted orthopedic surgery systems will enable surgeons to better assess the accuracy and reliability of the various operative techniques, an indispensable stage in the optimization of surgery.

  5. Climate Projection Data base for Roads - CliPDaR: Design a guideline for a transnational database of downscaled climate projection data for road impact models - within the Conference's of European Directors of Roads (CEDR) TRANSNATIONAL ROAD RESEARCH PROG

    Science.gov (United States)

    Matulla, Christoph; Namyslo, Joachim; Fuchs, Tobias; Türk, Konrad

    2013-04-01

    The European road sector is vulnerable to extreme weather phenomena, which can cause large socio-economic losses. Almost every year there occur several weather triggered events (like heavy precipitation, floods, landslides, high winds, snow and ice, heat or cold waves, etc.), that disrupt transportation, knock out power lines, cut off populated regions from the outside and so on. So, in order to avoid imbalances in the supply of vital goods to people as well as to prevent negative impacts on health and life of people travelling by car it is essential to know present and future threats to roads. Climate change might increase future threats to roads. CliPDaR focuses on parts of the European road network and contributes, based on the current body of knowledge, to the establishment of guidelines helping to decide which methods and scenarios to apply for the estimation of future climate change based challenges in the field of road maintenance. Based on regional scale climate change projections specific road-impact models are applied in order to support protection measures. In recent years, it has been recognised that it is essential to assess the uncertainty and reliability of given climate projections by using ensemble approaches and downscaling methods. A huge amount of scientific work has been done to evaluate these approaches with regard to reliability and usefulness for investigations on possible impacts of climate changes. CliPDaR is going to collect the existing approaches and methodologies in European countries, discuss their differences and - in close cooperation with the road owners - develops a common line on future applications of climate projection data to road impact models. As such, the project will focus on reviewing and assessing existing regional climate change projections regarding transnational highway transport needs. The final project report will include recommendations how the findings of CliPDaR may support the decision processes of European

  6. Digital temperature meter

    Energy Technology Data Exchange (ETDEWEB)

    Glowacki, S

    1982-01-01

    Digital temperature meter for precise temperature measurements is presented. Its parts such as thermostat, voltage-frequency converter and digital frequency meter are described. Its technical parameters such as temperature range 50degC-700degC, measurement precision 1degC, measurement error +-1degC are given. (A.S.).

  7. Changing State Digital Libraries

    Science.gov (United States)

    Pappas, Marjorie L.

    2006-01-01

    Research has shown that state virtual or digital libraries are evolving into websites that are loaded with free resources, subscription databases, and instructional tools. In this article, the author explores these evolving libraries based on the following questions: (1) How user-friendly are the state digital libraries?; (2) How do state digital…

  8. Digital signage sobre IP

    OpenAIRE

    Casademont Filella, Albert

    2012-01-01

    Projecte que versa sobre el disseny i la implementació d'un sistema de Digital Signage (Cartelleria Digital) sobre IP, creant un gestor que permeti controlar de forma remota tot un conjunt de petits dispositius connectats a pantalles que emeten continguts multimèdia com vídeos, imatges, feeds rss...

  9. Digital gaming expertise

    DEFF Research Database (Denmark)

    Toft-Nielsen, Claus

    In a digitally saturated environment digital media users of all kinds, engaged in different areas of activity, are increasingly categorized in terms of their ability to appropriate and use digital media – they are regarded as non-users, experts, natives, or literates for instance. Within communic......In a digitally saturated environment digital media users of all kinds, engaged in different areas of activity, are increasingly categorized in terms of their ability to appropriate and use digital media – they are regarded as non-users, experts, natives, or literates for instance. Within...... communication and game studies there are multiple understandings of how digital expertise is expressed and performed, and subsequently how these expressions and performances can be valued, understood and theorized within the research community. Among other things expertise with and within digital games has......-of-game (Schrøder, 2003) in a three-year-long study of men and women (couples and singles) playing the largest Massively Multiplayer Online Role-Playing Game to date, World of Warcraft. In focusing on how different aspects of gaming expertise are articulated, negotiated, and performed, I aim to illustrate how...

  10. The First Digit 1

    Indian Academy of Sciences (India)

    IAS Admin

    1075. RESONANCE | December 2013. GENERAL | ARTICLE. Table 2. The first digits distri- bution according to Benford's law. First Frequency. Digit. 1. 30.1 %. 2. 17.6 %. 3. 12.4 %. 4. 9.7 %. 5. 7.9 %. 6. 6.7 %. 7. 5.8 %. 8. 5.1 %. 9. 4.5 % ...

  11. Digital Cultural Heritage

    NARCIS (Netherlands)

    Navarrete, T.; Rizzo, I.; Mignosa, A.

    2013-01-01

    What is the impact of media technology on the supply and demand of heritage with what is usually described as digitization? This chapter presents the concept of digitization as concerning far more than just the introduction of computers, the development of databases and websites, and the conversion

  12. Digital formidling af kulturarv

    DEFF Research Database (Denmark)

    En af tidens store kulturelle dagsordner drejer sig om digital tilgængeliggørelse af kulturarv. Fortidens spor dukker op i nye former på nettet - næsten alle kulturinstitutioner arbejder med, og befolkningen har fået helt nye muligheder for at se med og deltage. Digital formidling af kulturarv...

  13. Digitizing migration heritage

    DEFF Research Database (Denmark)

    Marselis, Randi

    2011-01-01

    Museums are increasingly digitizing their collections and making them available to the public on-line. Creating such digital resources may become means for social inclusion. For museums that acknowledge migration history and cultures of ethnic minority groups as important subjects in multiethnic...

  14. Beyond Digital Citizenship

    Science.gov (United States)

    Mitchell, Lynn

    2016-01-01

    Conversations in middle school about digital citizenship tend to focus on the responsibilities of citizenship and the issues of surveillance, safety, cyberbullying, and internet etiquette. While these are important and essential conversations, digital citizenship education needs to consider youth political identity and democratic participation in…

  15. Navigate the Digital Rapids

    Science.gov (United States)

    Lindsay, Julie; Davis, Vicki

    2010-01-01

    How can teachers teach digital citizenship when the digital landscape is changing so rapidly? How can teachers teach proper online social interactions when the students are outside their classroom and thus outside their control? Will encouraging students to engage in global collaborative environments land teachers in hot water? These are the…

  16. Monetizing Digital Assets

    Directory of Open Access Journals (Sweden)

    Felician ALECU

    2013-04-01

    Full Text Available This article covers the options the digital content creators have to monetize their creations. The simplest solution seems to be the winning one, so by enabling the ads, the digital content may be quickly transformed into money with no cost.

  17. Digital chest radiography

    DEFF Research Database (Denmark)

    Debess, Jeanne Elisabeth; Johnsen, Karen Kirstine; Thomsen, Henrik

    on collimation and dose reduction in digital chest radiography Methods and Materials A retrospective study of digital chest radiography is performed to evaluate the primary x-ray tube collimation of the PA and lateral radiographs. Data from one hundred fifty self-reliant female patients between 15 and 55 years...

  18. Recurrent infantile digital fibromatosis

    African Journals Online (AJOL)

    We present a case of an 8-year-old-boy with recurrent infantile digital fibromatosis (IDF) who presented with new ... Keywords: fibrous tumors, inclusion body fibromatosis, infantile digital fibromatosis, spindle cells, Reye tumor .... watch-and-wait strategy for patients with histologically confirmed IDF nodules that do not cause ...

  19. Practical digital mammography

    Energy Technology Data Exchange (ETDEWEB)

    Hashimoto, Beverly E. [Washington Univ., Seattle, WA (United States)]|[Virginia Mason Medical Center, VA (United States)

    2008-07-01

    This book is meant for the radiologist who is facing the challenge of organizing a digital mammographic imaging center. This text is meant to be a practical book that provides information about digital mammographic physics and equipment which will allow one to intelligently compare technologies and systems. Some of the major challenges include: large expense; rapidly changing technology, and inconsistent connectivity; and finally, need for strong information technology support. The initial conversion cost to digital mammographic imaging is relatively expensive due to the cost of digital mammography hardware, software, and storage. Virtually all other imaging modalities are being converted to purely digital storage and transfer, and the digital trend in mammography is inevitable. Technical advantages of digital mammography are described. However, the improved flexibility in image display and transfer are some of its strongest features. In conclusion, although there are increasing imaging modalities that may be used to evaluate breast disease, mammography will continue to play a key role in detecting breast cancer. To be an effective imager, the radiologist should become familiar with digital mammography and understand its role within the increasing complex structure of breast imaging techniques.

  20. Practical digital mammography

    International Nuclear Information System (INIS)

    Hashimoto, Beverly E.

    2008-01-01

    This book is meant for the radiologist who is facing the challenge of organizing a digital mammographic imaging center. This text is meant to be a practical book that provides information about digital mammographic physics and equipment which will allow one to intelligently compare technologies and systems. Some of the major challenges include: large expense; rapidly changing technology, and inconsistent connectivity; and finally, need for strong information technology support. The initial conversion cost to digital mammographic imaging is relatively expensive due to the cost of digital mammography hardware, software, and storage. Virtually all other imaging modalities are being converted to purely digital storage and transfer, and the digital trend in mammography is inevitable. Technical advantages of digital mammography are described. However, the improved flexibility in image display and transfer are some of its strongest features. In conclusion, although there are increasing imaging modalities that may be used to evaluate breast disease, mammography will continue to play a key role in detecting breast cancer. To be an effective imager, the radiologist should become familiar with digital mammography and understand its role within the increasing complex structure of breast imaging techniques

  1. Educating Digital Citizens

    Science.gov (United States)

    Tan, Thomas

    2011-01-01

    Digital citizenship is how educators, citizens, and parents can teach where the lines of cyber safety and ethics are in the interconnected online world their students will inhabit. Aside from keeping technology users safe, digital citizenship also prepares students to survive and thrive in an environment embedded with information, communication,…

  2. Digital Rights Management

    NARCIS (Netherlands)

    Koster, P.; Jonker, Willem; Blanken, Henk; de Vries, A.P.; Blok, H.E.; Feng, L.

    2007-01-01

    Digital Rights Management, or DRM for short, is a much-discussed topic nowadays. The main reason for this is that DRM technology is often mentioned in the context of protection of digital audio and video content, for example to avoid large scale copying of CDs and DVDs via peer-to-peer networks in

  3. Assisting digital forensics investigations by identifying social communication irregularities

    CSIR Research Space (South Africa)

    Pieterse, Heloise

    2017-06-01

    Full Text Available People are creatures of habit, favouring the familiar over unpredictability, which causes them to usually follow set patterns or routines. This is especially true for social interaction or communication where people tend to prefer familiar or well...

  4. Born Digital? Pedagogy and Computer-Assisted Learning

    Science.gov (United States)

    Clarke, Thomas; Clarke, Elizabeth

    2009-01-01

    Purpose: The purpose of this article is to examine the impact of the shift to a knowledge society, where information and communication technology (ICT) and the widening spread of internationally distributed information are creating a "skill revolution", as O'Hara suggests, there is a widening culture mismatch between what members of the knowledge…

  5. Impacts of Digital Imaging versus Drawing on Student Learning in Undergraduate Biodiversity Labs

    Science.gov (United States)

    Basey, John M.; Maines, Anastasia P.; Francis, Clinton D.; Melbourne, Brett

    2014-01-01

    We examined the effects of documenting observations with digital imaging versus hand drawing in inquiry-based college biodiversity labs. Plant biodiversity labs were divided into two treatments, digital imaging (N = 221) and hand drawing (N = 238). Graduate-student teaching assistants (N = 24) taught one class in each treatment. Assessments…

  6. Digitalization of daycare institutions

    DEFF Research Database (Denmark)

    Chimirri, Niklas Alexander

    in the intergenerational interaction with as well as the intragenerational interaction among daycare children. To some extent, digital media usage, foremost of tablet computers, has seen a discursive and material normalization across a number Danish daycare institutions before at all clarifying how it could be rendered...... as on situated sociomaterial approaches to critical psychological practice research in order to inquire into possible specificities of digital media device usage: How is this usage similar to and different from interacting via other material-communicative devices in a pedagogical practice? How do digital media......The digitalization of Danish daycare institutions is not only affecting the ways staff is documenting and reporting on its pedagogical work. It also appears to be redefining what pedagogical work itself is about, given the drastic increase in deployment of digital (mobile) media devices...

  7. Creative Digital Media Practices

    DEFF Research Database (Denmark)

    Frølunde, Lisbeth

    , 2006, 2009), machinima (machine + cinema + anime, real-time animation captured in games etc.), and the digital storytelling movement. A dialogic perspective on the diversity of digital media practices opens up for understanding the complex evolution of language on socio-historical, cultural......The presentation reviews the interplay of dialogic (Bakhtin, 1981) and multimodal theories on media production practices, with attention to visual communication (Kress and van Leeuwen, 2001, 2006). This theoretical approach aids in reflecting on digital media practices as novel (new) sign systems...... develop a collaborative digital storytelling showcase for their own digital stories about Roskilde University. This course is intended to bring up reflections on the wider phenomenon of contemporary media practices, such as: YouTube, DIY (do-it-yourself) filmmaking or homemade, garage cinema (Jenkins...

  8. Digital Technology Entrepreneurship

    DEFF Research Database (Denmark)

    Giones, Ferran; Brem, Alexander

    2017-01-01

    Technology entrepreneurship is an established concept in academia. However, recent developments in the context of digital entrepreneurship call for revision and advance- ment. The multiple possible combinations of technology and entrepreneurship have res- ulted in a diversity of phenomena...... with significantly different characteristics and socio-economic impact. This article is focused on the identification and description of technology entrepreneurship in times of digitization. Based on current examples, we identify and describe characterizations of technology entrepreneurship, digital techno- logy...... entrepreneurship, and digital entrepreneurship. With this new delineation of terms, we would like to foster discussion between researchers, entrepreneurs, and policy makers on the impact of digitization on entrepreneurship, and set a future research agenda....

  9. Transformation of Digital Ecosystems

    DEFF Research Database (Denmark)

    Henningsson, Stefan; Hedman, Jonas

    2014-01-01

    the Digital Ecosystem Technology Transformation (DETT) framework for explaining technology-based transformation of digital ecosystems by integrating theories of business and technology ecosystems. The framework depicts ecosystem transformation as distributed and emergent from micro-, meso-, and macro- level......In digital ecosystems, the fusion relation between business and technology means that the decision of technical compatibility of the offering is also the decision of how to position the firm relative to the coopetive relations that characterize business ecosystems. In this article we develop...... coopetition. The DETT framework consists an alternative to the existing explanations of digital ecosystem transformation as the rational management of one central actor balancing ecosystem tensions. We illustrate the use of the framework by a case study of transformation in the digital payment ecosystem...

  10. The digital spine

    DEFF Research Database (Denmark)

    Ebbesen, Toke Riis

    2019-01-01

    In the words of the Oxford English Dictionary, a book is 'a portable volume consisting of a series of written, printed, or illustrated pages bound together for ease of reading' (‘book, n.’nd). Yet, the world of books isn’t what it used to be. If differences between media are material differences...... analyze books as digital or even 'post-digital' artifacts (Cramer 2014), while preserving the material dimension of the book artifact. In other words: is there is such a thing as a (post-)digital spine, and how can it be described? This article outlines an answer to this question within an inferential...... (Seiter 2015), and books are produced, distributed and read on various digital media and devices, it is no longer possible to understand digital books on the basis of the material and syntactical features of the codex artifact. It then becomes important to discuss how to conceptualize and subsequently...

  11. Digital Tectonic Tools

    DEFF Research Database (Denmark)

    Schmidt, Anne Marie Due

    2005-01-01

    Tectonics has been an inherent part of the architectural field since the Greek temples while the digital media is new to the field. This paper is built on the assumption that in the intermediate zone between the two there is a lot to be learned about architecture in general and the digital media...... in particular. A model of the aspects in the term tectonics – epresentation, ontology and culture – will be presented and used to discuss the current digital tools’ ability in tectonics. Furthermore it will be discussed what a digital tectonic tool is and could be and how a connection between the digital...... and tectonic could become a part of the architectural education....

  12. Digital forensic standards: international progress

    CSIR Research Space (South Africa)

    Grobler, MM

    2010-05-01

    Full Text Available With the explosion of digital crime, digital forensics is more often applied. The digital forensic discipline developed rather rapidly, but up to date very little international standardization with regard to processes, procedures or management has...

  13. Spatially-resolved, three-dimensional spray characterization of impinging jets by digital in-line holography

    Science.gov (United States)

    Gao, Jian; Rodrigues, Neil; Sojka, Paul; Chen, Jun

    2014-11-01

    The impinging jet injector is a preferred method for the atomization of liquid rocket propellants. The majority of experimental studies in literature are not spatially-resolved due to the limitations of widely available point-wise and two-dimensional (2D) diagnostic techniques such as phase Doppler anemometry (PDA), which requires significant experimental repetitions to give spatially-resolved measurements. In the present study, digital in-line holography (DIH) is used to provide spatially-resolved, three-dimensional (3D) characteristics of impinging jet sprays. A double-exposure DIH setup is configured to measure droplet 3D, three-component velocity as well as the size distribution. The particle information is extracted by the hybrid method, which is recently proposed as a particle detection method. To enlarge the detection volume, two parallel, collimated laser beams are used to simultaneously probe the spray at two locations, and two identical cameras are used to record the corresponding holograms. Such a setup has a detection volume of approximately 20 cm by 3.6 cm by 4.8 cm. Sprays of both Newtonian and non-Newtonian liquids corresponding to regimes at relatively lower jet Reynolds and Weber numbers are investigated. Measurements from DIH are further verified by comparison with experimental data obtained from shadowgraph and PDA. It is revealed that DIH is particularly suitable to provide spatially-resolved, 3D measurements of impinging jet sprays that are not particularly dense.

  14. Computing Logarithms Digit-by-Digit

    Science.gov (United States)

    Goldberg, Mayer

    2005-01-01

    In this work, we present an algorithm for computing logarithms of positive real numbers, that bears structural resemblance to the elementary school algorithm of long division. Using this algorithm, we can compute successive digits of a logarithm using a 4-operation pocket calculator. The algorithm makes no use of Taylor series or calculus, but…

  15. Principles of synchronous digital hierarchy

    CERN Document Server

    Jain, Rajesh Kumar

    2012-01-01

    The book presents the current standards of digital multiplexing, called synchronous digital hierarchy, including analog multiplexing technologies. It is aimed at telecommunication professionals who want to develop an understanding of digital multiplexing and synchronous digital hierarchy in particular and the functioning of practical telecommunication systems in general. The text includes all relevant fundamentals and provides a handy reference for problem solving or defining operations and maintenance strategies. The author covers digital conversion and TDM principles, line coding and digital

  16. Research on Digital Product Modeling Key Technologies of Digital Manufacturing

    Institute of Scientific and Technical Information of China (English)

    DING Guoping; ZHOU Zude; HU Yefa; ZHAO Liang

    2006-01-01

    With the globalization and diversification of the market and the rapid development of Information Technology (IT) and Artificial Intelligence (AI), the digital revolution of manufacturing is coming. One of the key technologies in digital manufacturing is product digital modeling. This paper firstly analyzes the information and features of the product digital model during each stage in the product whole lifecycle, then researches on the three critical technologies of digital modeling in digital manufacturing-product modeling, standard for the exchange of product model data and digital product data management. And the potential signification of the product digital model during the process of digital manufacturing is concluded-product digital model integrates primary features of each stage during the product whole lifecycle based on graphic features, applies STEP as data exchange mechanism, and establishes PDM system to manage the large amount, complicated and dynamic product data to implement the product digital model data exchange, sharing and integration.

  17. Interfaces for Modular Surgical Planning and Assistance Systems

    OpenAIRE

    Gessat, Michael

    2010-01-01

    Modern surgery of the 21st century relies in many aspects on computers or, in a wider sense, digital data processing. Department administration, OR scheduling, billing, and - with increasing pervasion - patient data management are performed with the aid of so called Surgical Information Systems (SIS) or, more general, Hospital Information Systems (HIS). Computer Assisted Surgery (CAS) summarizes techniques which assist a surgeon in the preparation and conduction of surgical interventions...

  18. Digital health technology and diabetes management.

    Science.gov (United States)

    Cahn, Avivit; Akirov, Amit; Raz, Itamar

    2018-01-01

    Diabetes care is largely dependent on patient self-management and empowerment, given that patients with diabetes must make numerous daily decisions as to what to eat, when to exercise, and determine their insulin dose and timing if required. In addition, patients and providers are generating vast amounts of data from many sources, including electronic medical records, insulin pumps, sensors, glucometers, and other wearables, as well as evolving genomic, proteomic, metabolomics, and microbiomic data. Multiple digital tools and apps have been developed to assist patients to choose wisely, and to enhance their compliance by using motivational tools and incorporating incentives from social media and gaming techniques. Healthcare teams (HCTs) and health administrators benefit from digital developments that sift through the enormous amounts of patient-generated data. Data are acquired, integrated, analyzed, and presented in a self-explanatory manner, highlighting important trends and items that require attention. The use of decision support systems may propose data-driven actions that, for the most, require final approval by the patient or physician before execution and, once implemented, may improve patient outcomes. The digital diabetes clinic aims to incorporate all digital patient data and provide individually tailored virtual or face-to-face visits to those persons who need them most. Digital diabetes care has demonstrated only modest HbA1c reduction in multiple studies and borderline cost-effectiveness, although patient satisfaction appears to be increased. Better understanding of the barriers to digital diabetes care and identification of unmet needs may yield improved utilization of this evolving technology in a safe, effective, and cost-saving manner. © 2017 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and John Wiley & Sons Australia, Ltd.

  19. DSA in digital replantations

    International Nuclear Information System (INIS)

    Wang Liuhong; Chao Ming; Jiang Dingyao; Zhang Guangqiang; Wu Jianjun; Chen Xianyi; Li Bin; Sun Jihong

    2008-01-01

    Objective: To assess revascularization and vessel anastomosis in digital replantations with DSA. Methods: Twelve cases of digital replantations underwent digital subtract angiography during 2 to 4 days after fingers reattachment. The vessel anastomosis, hemodynamics, stenosis and discontinuation were investigated. The unobstructed and smooth anastomosis was suggested as early stage survival of the reattached fingers, the spasm and stenosis of the reattached vessels were considered as mild vascular crisis, and the discontinuation of hemodynamics were indicated as severe vascular crisis. Results: The total 27 vessels were clearly displayed on DSA. Of these vessels, 23 vessels were unobstructed and smooth, all digits were survived. Diagnosis coincidence of early stage survival was 100% (23/23). Two vessels were obstructed, which were testified having thrombus by operation research. The other 2 vessels were spasm, the digits were also survived ultimately by expectant treatment. All 4 abnormal vessel anatomosis were found by DSA. Conclusion: DSA is important modality in assessing revascularization and blood circulation for digital replantations, guiding in dealing with the vascular crisis, and in predicting early stage survival of the reattached digits. (authors)

  20. Digital mineral logging system

    International Nuclear Information System (INIS)

    West, J.B.

    1980-01-01

    A digital mineral logging system acquires data from a mineral logging tool passing through a borehole and transmits the data uphole to an electronic digital signal processor. A predetermined combination of sensors, including a deviometer, is located in a logging tool for the acquisition of the desired data as the logging tool is raised from the borehole. Sensor data in analog format is converted in the logging tool to a digital format and periodically batch transmitted to the surface at a predetermined sampling rate. An identification code is provided for each mineral logging tool, and the code is transmitted to the surface along with the sensor data. The self-identifying tool code is transmitted to the digital signal processor to identify the code against a stored list of the range of numbers assigned to that type of tool. The data is transmitted up the d-c power lines of the tool by a frequency shift key transmission technique. At the surface, a frequency shift key demodulation unit transmits the decoupled data to an asynchronous receiver interfaced to the electronic digital signal processor. During a recording phase, the signals from the logging tool are read by the electronic digital signal processor and stored for later processing. During a calculating phase, the stored data is processed by the digital signal processor and the results are outputted to a printer or plotter, or both

  1. Digital cardiovascular imaging

    International Nuclear Information System (INIS)

    Myerowitz, P.D.; Mistretta, C.A.; Shaw, C.-G.; Van Lysel, M.S.; Swanson, D.K.; Lasser, T.A.; Dhanani, S.P.; Zarnstorff, W.C.; Vander Ark, C.R.; Dobbins, J.T.; Peppler, W.W.; Crummy, A.B.

    1982-01-01

    The authors have previously reported on real time digital fluoroscopic subtraction techniques developed in the laboratory during the past 10 years. This paper outlines basic apparatus configuration and imaging modes used for preliminary studies involving visualization of the canine and human heart. All of the techniques involve the use of real time digital subtraction processing of data from an image intensified television fluoroscopy system. Based on the configuration of the digital processing equipment a number of different imaging modalities are possible. A brief description of the apparatus and these imaging modes is given. (Auth.)

  2. Digital Enlightenment Yearbook 2012

    CERN Document Server

    Bus, J; Hildebrandt, M

    2012-01-01

    There have been many inevitable transformations in society due to digitization - the introduction of digital technology, including communication technology, through the Internet and its use via the Web.This book is the first Yearbook of the Digital Enlightenment Forum. Whilst it cannot cover all the many aspects which the forum encompasses, the book gives an impression of the broad spectrum of the forum and a clear picture of the multi-disciplinary nature of the issues at stake.The first paper in the book is a contribution from the father of the Web, Sir Tim Berners-Lee, and Harry Halpin. They

  3. Fast transient digitizer

    International Nuclear Information System (INIS)

    Villa, F.

    1982-01-01

    Method and apparatus for sequentially scanning a plurality of target elements with an electron scanning beam modulated in accordance with variations in a high-frequency analog signal to provide discrete analog signal samples representative of successive portions of the analog signal; coupling the discrete analog signal samples from each of the target elements to a different one of a plurality of high speed storage devices; converting the discrete analog signal samples to equivalent digital signals; and storing the digital signals in a digital memory unit for subsequent measurement or display

  4. Digital Marketing Communication

    OpenAIRE

    Margherita Corniani

    2006-01-01

    Digital marketing communication is directed to profiled targets, which are active in the communication process. Every communication flow can ask for an information answer from the market. This opportunity grants immediate feed-backs and feed-forwards, so that digital communication can be easily and cheaply measured; digital communication flows are diffused at costs that are getting lower and lower, but it asks specialized and deep competences to communication managers. The ease in the flowing...

  5. plano de Marketing Digital

    OpenAIRE

    Bento, Daniel Jorge Cunha Correia

    2015-01-01

    O projeto aqui apresentado consiste no desenvolvimento de um plano estratégico de marketing digital para o projeto Laboratório de Criação Digital (LCDPorto). O LCDPorto tem sete anos de existência, sem nunca ter definido uma estratégia de comunicação. O principal objetivo passa por aprofundar os vários temas que integram Marketing Digital, e desenvolver um plano que permita ao LCDPorto ganhar mais notoriedade pelas atividades que desenvolve e, também, obter mais público para...

  6. Transitioning to digital radiography

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, F., E-mail: Francisco.Miranda@pwc.ca [Pratt & Whitney Canada, Longueuil, Quebec (Canada)

    2015-09-15

    This article provides insight on the technical and business considerations necessary to implement or to transition to digital radiography Continued refinements in digital radiography technology have resulted in significant improvements in image quality and detectability of indications. These improvements have resulted in the acceptance of the technology by users and aerospace primes for final product inspection and disposition. Digital radiography has also been identified as an interesting cost reduction initiative with the potential of providing gains in productivity through increased throughput and decreased inspection lead-times and resulting costs. (author)

  7. The Digital Marmor Parium

    OpenAIRE

    Berti, Monica

    2017-01-01

    The Digital Marmor Parium is a project of the Alexander von Humboldt Chair of Digital Humanities at the University of Leipzig (http://www.dh.uni-leipzig.de/wo/dmp). The aim of this work is to produce a new digital edition of the so called Marmor Parium (Parian Marble), which is a Hellenistic chronicle on a marble slab coming from the Greek island of Paros. The importance of the document is due to the fact that it preserves a Greek chronology (1581/80-299/98 BC) with a list of kings and archon...

  8. Advanced Digital Preservation

    CERN Document Server

    Giaretta, David

    2011-01-01

    There is growing recognition of the need to address the fragility of digital information, on which our society heavily depends for smooth operation in all aspects of daily life. This has been discussed in many books and articles on digital preservation, so why is there a need for yet one more? Because, for the most part, those other publications focus on documents, images and webpages -- objects that are normally rendered to be simply displayed by software to a human viewer. Yet there are clearly many more types of digital objects that may need to be preserved, such as databases, scientific da

  9. Digitization in Maritime Industry

    DEFF Research Database (Denmark)

    Constantiou, Ioanna; Shollo, Arisa; Kreiner, Kristian

    2017-01-01

    Digitization in the maritime industry is expected to transform businesses. The recently introduced mobile technologies in inter-organizational processes is an example of digitization in an industry which moves very slowly towards digital transformation. We focus on the influence of mobile...... technologies on control practices in inter-organizational processes related to coping with an engine failure. We collected qualitative data from in depth interviews with representatives of the involved parties. We identify organizational and behavioural challenges hindering information sharing during problem...... technologies increase information sharing and thus the efficiency of inter-organizational processes when coping with an engine failure....

  10. Digital archives. Alcune note

    Directory of Open Access Journals (Sweden)

    Francesca Zanella

    2014-12-01

    Full Text Available MoRE is a digital native museum where projects of artworks are exposed, and also a digital archive where documents about art projectsare collected. MoRE is a multi-layered platform where artists, curators, art historians confront each other collecting art projects, organizing their documentation and defining tools for the communication and surveys on the public. In this paper some critical referencesare identified, that constitute a model for the project as they reflect on the impact of the digital dimension on the transformation of the museum and archive.

  11. Sandwich-Type Electrochemiluminescence Sensor for Detection of NT-proBNP by Using High Efficiency Quench Strategy of Fe3O4@PDA toward Ru(bpy)32+ Coordinated with Silver Oxalate.

    Science.gov (United States)

    Shi, Li; Li, Xiaojian; Zhu, Wenjuan; Wang, Yaoguang; Du, Bin; Cao, Wei; Wei, Qin; Pang, Xuehui

    2017-12-22

    Heart failure (HF) is a burgeoning public health problem trigged by a heart circulation disorder. N-terminal pro-B-type natriuretic peptide (NT-proBNP) has been acknowledged as a prognostic biomarker for cardiac disease. Herein, a sandwich-type electrochemiluminescence (ECL) immunosensor was introduced for sensitive detection of NT-proBNP. Gold nanoparticle modified graphene oxide-Ru(bpy) 3 2+ /Ag 2 C 2 O 4 was used as a luminophore and a desirable platform for immobilization of the captured antibodies. The more stable immobilization of plentiful Ru(bpy) 3 2+ could be implemented by direct covalent bonding chelation with Ag 2 C 2 O 4 . More importantly, significant quenching can be achieved by introducing polydopamine (PDA) coated Fe 3 O 4 onto the electrode via sandwich immunoreactions. The quenching mechanism mainly showed that the excited states of Ru(bpy) 3 2+ could be annihilated by quinone units in PDA via energy transfer. The ECL quenching efficiency was logarithmically related to the concentration of the NT-proBNP in the range from 0.0005 ng/mL to 100.0 ng/mL with a detection limit of 0.28 pg/mL. Furthermore, this specific immunosensor presented good stability and repeatability as well as selectivity, which offers a guiding significance in both fundamental and clinical diagnosis of NT-proBNP.

  12. Ultrasensitive multi-analyte electrochemical immunoassay based on GNR-modified heated screen-printed carbon electrodes and PS@PDA-metal labels for rapid detection of MMP-9 and IL-6.

    Science.gov (United States)

    Shi, Jian-Jun; He, Ting-Ting; Jiang, Fang; Abdel-Halim, E S; Zhu, Jun-Jie

    2014-05-15

    An ultrasensitive electrochemical immunoassay was developed for rapid detection of interleukin-6 (IL-6) and matrix metallopeptidase-9 (MMP-9); the method utilized PS@PDA-metal nanocomposites based on graphene nanoribbon (GNR)-modified heated screen-printed carbon electrode (HSPCE). Because of the good hydrophilicity and low toxicity, GNRs were used to immobilize antibodies (Ab) and amplify the electrochemical signal. PS@PDA-metal was used to label antibodies and generate a strong electrochemical signal in acetic buffer. A sandwich strategy was adopted to achieve simultaneous detection of MMP-9 and IL-6 based on HSPCE without cross-talk between adjacent electrodes in the range of 10(-5) to 10(3) ng mL(-1) with detection limits of 5 fg mL(-1) and 0.1 pg mL(-1) (S/N=3), respectively. The proposed method showed wide detection range, low detection limit, acceptable stability and good reproducibility. Satisfactory results were also obtained in the practical samples, thus showing this is a promising technique for simultaneous clinical detection of biocomponent proteins. © 2013 Elsevier B.V. All rights reserved.

  13. Isolation and structural characterization of a novel sibutramine analogue, chlorosipentramine, in a slimming dietary supplement, by using HPLC-PDA, LC-Q-TOF/MS, FT-IR, and NMR.

    Science.gov (United States)

    Yun, Jisuk; Shin, Kye Jung; Choi, Jangduck; Jo, Cheon-Ho

    2018-05-01

    A novel sibutramine analogue was detected in a slimming formula by high performance liquid chromatography with a photo diode detector array (HPLC-PDA). The unknown compound exhibited an ultraviolet (UV) spectrum that was similar to that of chlorosibutramine, despite having a different HPLC retention time. Further analysis of the slimming formula by LC-quadrupole time-of-flight mass spectrometry (LC-Q-TOF/MS) showed that the unknown compound had the formula C 18 H 27 Cl 2 N. To elucidate the structure of this new sibutramine analogue, the target compound in the slimming formula was isolated on a preparative-LC system equipped with a PDA. After analysis by fourier transform infrared (FT-IR) and nuclear magnetic resonance (NMR) spectroscopy, the unknown compound was identified as a sibutramine analogue in which the iso-butyl group on the side chain is replaced with an iso-pentyl group. This new sibutramine analogue was identified to be 1-(1-(3,4-dichlorophenyl)cyclobutyl)-N,N,4-trimethylpentan-1-amine and has been named as chlorosipentramine. Copyright © 2018 Elsevier B.V. All rights reserved.

  14. Der Einsatz von PDAs durch Ärzte/Ärztinnen im Stationsalltag und in der Praxis / Physician's use of PDAs in clinic and general practice

    Directory of Open Access Journals (Sweden)

    Offenberger, Wolfgang

    2008-09-01

    Full Text Available Beside its basic functionality the Personal Digital Assistant (PDA offers interesting features to the medical doctor working in a clinic or general practice. However, these possibilities are often unknown even to the medical professional. This paper introduces medical software for the PDA which is helpful in the daily routine in order to have valuable information at hand at the point-of-care.

  15. Digital Library and Digital Reference Service: Integration and Mutual Complementarity

    Science.gov (United States)

    Liu, Jia

    2008-01-01

    Both the digital library and the digital reference service were invented and have been developed under the networked environment. Among their intersections, the fundamental thing is their symbiotic interest--serving the user in a more efficient way. The article starts by discussing the digital library and its service and the digital reference…

  16. Digital Literacy Learning in Higher Education through Digital Storytelling Approach

    Science.gov (United States)

    Chan, Banny S. K.; Churchill, Daniel; Chiu, Thomas K. F.

    2017-01-01

    It is necessary to develop digital literacy skills with which students can communicate and express their ideas effectively using digital media. The educational sectors around the world are beginning to incorporate digital literacy into the curriculum. Digital storytelling, one of the possible classroom activities, is an approach which may help…

  17. Digitization and digital archiving a practical guide for librarians

    CERN Document Server

    Leggett, Elizabeth R

    2014-01-01

    Modern library patrons are embracing the ease with which information can be accessed digitally, and so many librarians are currently working toward making information available electronically. Digitization and Digital Archiving: A Practical Guide for Librarians is a comprehensive guide with step-by-step instructions for forming digital archives.

  18. Digital Citizenship Means Character Education for the Digital Age

    Science.gov (United States)

    Ohler, Jason

    2012-01-01

    The reality of students' cyber lives has thrust upon educators a new approach: creating character education programs tuned to digital youth that are proactive and aggressive. This will help integrate students' digital activities within the context of the communities in which they live, both local and digital. The digital age beckons a new era of…

  19. Fast digitization and digital receiver technology

    International Nuclear Information System (INIS)

    Kimball, Ralph C.

    2002-01-01

    The potentially lucrative wireless market has led to technological advances in mixed signal devices such as high speed, high resolution A/D and D/A converters. This same market has also driven the development of high performance multi-channel digital receiver and digital transmitter ICs. Similarly, advances in semiconductor processes, coupled with the need for reduced time-to-market, has led to the development of large, enhanced performance, in-circuit programmable logic devices. A review of the key characteristics of these mixed-signal, signal processing and programmable logic devices is presented. The application of these devices and technologies to the instrumentation of Accelerators and Storage Rings is discussed and presented by way of examples. Issues relating to the requirements associated with real-time processing, I/O throughput, reconfigurability, reliability, maintainability and packaging requirements are also addressed

  20. Digital literacies at school. Students' digital profiles

    Directory of Open Access Journals (Sweden)

    Valentina Pennazio

    2013-04-01

    Full Text Available L’articolo presenta una ricerca volta a focalizzare le modalità in cui la Digital Literacy si traduce a scuola. Lo studio ha inteso sottolineare le molteplici dimensioni della Digital Literacy: Information Technology Literacy; Information Literacy; Visual Literacy e Media Literacy ed è stato effettuato nelle scuole primarie e secondarie di primo grado in Liguria. Sono state organizzate settimane di attività di ricerca, analisi e rielaborazione di informazioni, in classe e in rete, individualmente e in gruppo. Dalle autovalutazione degli studenti, svolte al termine di ogni attività, sono emersi i profili digitali che gli studenti tendono ad assumere quando utilizzano le tecnologie digitali. Tali profili possono essere utilizzati dagli insegnanti per progettare in maniera più mirata e significativa le attività con le tecnologie a scuola.

  1. Metacognitive factors that impact student nurse use of point of care technology in clinical settings.

    Science.gov (United States)

    Kuiper, RuthAnne

    2010-01-01

    The utility of personal digital assistants (PDA) as a point of care resource in health care practice and education presents new challenges for nursing faculty. While there is a plethora of PDA resources available, little is known about the variables that effect student learning and technology adoption. In this study nursing students used PDA software programs which included a drug guide, medical dictionary, laboratory manual and nursing diagnosis manual during acute care clinical experiences. Analysis of student journals comparative reflective statements about the PDA as an adjunct to other available resources in clinical practice are presented. The benefits of having a PDA included readily available data, validation of thinking processes, and facilitation of care plan re-evaluation. Students reported increased frequency of use and independence. Significant correlations between user perceptions and computer self-efficacy suggested greater confidence in abilities with technology resulting in increased self-awareness and achievement of learning outcomes.

  2. Use of an electronic cognitive aid by a person with Korsakoff syndrome.

    Science.gov (United States)

    de Joode, E A; van Boxtel, M P J; Hartjes, P; Verhey, F R J; van Heugten, C M

    2013-11-01

    The purpose of the current study was to evaluate the feasibility and the effectiveness of the use of a customized personal digital assistant (PDA) to support cognitive functioning in a person with Korsakoff syndrome. The PDA was compared with no external support and the use of a memory watch in a single case experimental design. Three main personal goal tasks were defined: "arrive at appointments on time", "execute a long-term task successfully", and "remember to ask for medication". No significant differences were found between the use of the memory watch and the use of the customized PDA. PDA use was perceived as feasible and effective and was considered as a more comprehensive aid than the memory watch. This study shows that a person with Korsakoff syndrome is able to use and benefit from a customized PDA. Replication of these findings in a larger effectiveness study is necessary.

  3. When Forgetting Becomes Digital

    DEFF Research Database (Denmark)

    Marton, Attila; Kallinikos, Jannis

    The structure of social memory is in a process of significant change as social operations of forgetting and remembering are increasingly written in IT and mediated in digital media. Based on an in-depth case study about the digitalization of memory institutions (libraries, archives, museums......), the paper demonstrates the emergence of a digital social memory structure that stores data as a means of forgetting. Building on such a concept, we explain the shifting structure of social memory from pre-defined, taxonomic order to algorithmic computation of artefacts and ordering. Finally, we draw...... implications from our study with regards to core organizational concepts of institutions and platforms as well as broader categories of information infrastructures and a sociology of digital knowledge....

  4. TV Digital Station Transmitters

    Data.gov (United States)

    Department of Homeland Security — This file is an extract from the Consolidated Database System (CDBS) licensed by the Media Bureau. It consists of Digital Television broadcasters (see Rule Part47...

  5. Digital pulse shape discrimination

    International Nuclear Information System (INIS)

    Miller, L. F.; Preston, J.; Pozzi, S.; Flaska, M.; Neal, J.

    2007-01-01

    Pulse-shape discrimination (PSD) has been utilised for about 40 years as a method to obtain estimates for dose in mixed neutron and photon fields. Digitizers that operate close to GHz are currently available at a reasonable cost, and they can be used to directly sample signals from photomultiplier tubes. This permits one to perform digital PSD rather than the traditional, and well-established, analogous techniques. One issue that complicates PSD for neutrons in mixed fields is that the light output characteristics of typical scintillators available for PSD, such as BC501A, vary as a function of energy deposited in the detector. This behaviour is more easily accommodated with digital processing of signals than with analogous signal processing. Results illustrate the effectiveness of digital PSD. (authors)

  6. Comprehension of digital media

    International Nuclear Information System (INIS)

    Kim, Ju Hwan

    2008-11-01

    This book is divided four parts. The first part describes media and mark on sign and media, what is the sign?, interpretation of sign and semiotics. The second part is for production sign theory and origin of digital revolution such as the problem of origin of digital revolution, homogeneity of producing goods and sign : triple triangle model for production sign theory, triple triangle model for producing goods, triple triangle model of producing sign and triple triangle model of art works. The third parts deals with development of the media and meaning of digital revolution with four changes : invention of letter, appearance of printed media and establishment modernity, appearance electronic media and mess media and appearance of digital media. The last part mentions ontology of world wide web.

  7. Students’ digital learning environments

    DEFF Research Database (Denmark)

    Caviglia, Francesco; Dalsgaard, Christian; Davidsen, Jacob

    2018-01-01

    The objective of the paper is to examine the nature of students’ digital learning environments to understand the interplay of institutional systems and tools that are managed by the students themselves. The paper is based on a study of 128 students’ digital learning environments. The objectives...... used tools in the students’ digital learning environments are Facebook, Google Drive, tools for taking notes, and institutional systems. Additionally, the study shows that the tools meet some very basic demands of the students in relation to collaboration, communication, and feedback. Finally...... of the study are 1) to provide an overview of tools for students’ study activities, 2) to identify the most used and most important tools for students and 3) to discover which activities the tools are used for. The empirical study reveals that the students have a varied use of digital media. Some of the most...

  8. Digital Mammography Tomosynthesis

    International Nuclear Information System (INIS)

    Gergov, I.; Alexov, G.; Rusonov, K.

    2017-01-01

    Siemens MAMMOMAT Inspiration with Tomosynthesis enhances the diagnostic precision in mammographic screening. The apparatus has a wide-angle tomosynthesis up to 50 degrees. The Siemens breast augmentation algorithm reconstructs multiple two-dimensional breast images into three-dimensional images at the lowest doses to help detect tumors hidden from the overlapping chest tissue, allowing for a more accurate diagnosis than standard 2-dimensional digital mammography, and reducing the number of false positive results. 3D digital tomosynthesis improves the precision of detecting and diagnosing a larger number of expansive lesions, ensures better morphological mass analysis and architectural distortion, and detecting calcifications by adding digital breast tomosynthesis to the traditional two-dimensional digital mammogram of the patient. In this way, it solves the problem of overlapping parenchyma, reduces the number of unnecessary biopsies from questionable sonomammographic findings, and the need for stressful repeating procedures, which usually contributes to both better patient outcomes and cost saving. [bg

  9. Digital image processing

    National Research Council Canada - National Science Library

    Gonzalez, Rafael C; Woods, Richard E

    2008-01-01

    Completely self-contained-and heavily illustrated-this introduction to basic concepts and methodologies for digital image processing is written at a level that truly is suitable for seniors and first...

  10. Academia Leads Digital Revolution

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ As the Chinese book publishing industry sits nervously on the edqe of possible market economy led reforms, one key area to address will be its ability to come to terms with the onset of digital publishing.

  11. Students’ digital learning environments

    DEFF Research Database (Denmark)

    Caviglia, Francesco; Dalsgaard, Christian; Davidsen, Jacob

    2018-01-01

    of the study are 1) to provide an overview of tools for students’ study activities, 2) to identify the most used and most important tools for students and 3) to discover which activities the tools are used for. The empirical study reveals that the students have a varied use of digital media. Some of the most......, the study shows that most of the important tools are not related to the systems provided by the educational institutions. Based on the study, the paper concludes with a discussion of how institutional systems connect to the other tools in the students’ practices, and how we can qualify students’ digital......The objective of the paper is to examine the nature of students’ digital learning environments to understand the interplay of institutional systems and tools that are managed by the students themselves. The paper is based on a study of 128 students’ digital learning environments. The objectives...

  12. Digital radiology. Clinical experience

    Energy Technology Data Exchange (ETDEWEB)

    Stacul, F; Smathers, R L

    1985-01-01

    The authors report the experience achieved ad the Stanford University (USA) with a digital radiography system which allows the digitization of the film and of the images collected with photostimulable phophors. The phophor is essentially an intensifying screen where a latent image is stored after exposure to X-rays and is extracted by a laser scanning. The images collected with the digitized film and with the phophor (chest, breast, bone) have been analyzed. The digitized film offers potential diagnostic advantages over the conventional film, because of the contrast manipulation and many other processing options. The possibility to recover the information of overexposed films appears very attractive. The photostimulable phophors allow to get good quality images, with a consistent reduction of dose and costs. These plates offer the possibility, in the next future, to replace the conventional screen-film systems.

  13. Performing Digital Literature

    Directory of Open Access Journals (Sweden)

    Jerome Fletcher

    2015-11-01

    Full Text Available Digital literature is a complex assemblage of related elements –material, spatial, linguistic, performative, textual, cultural, social– each of which is at one time interdependent and detached. This article discusses the literary creation within the cyberculture from the performativity point of view in relation to the textual apparatus. This is done through the analysis of a selection of performances where physical corporeality has a collaborative function with the body to a greater or lesser degree. Therefore, this physical feature can not only change, but stand at three possible and hybridizable axes: 1 the digital text as protagonist, 2 the digital text as counterpart, and 3 the digital text as site.

  14. Comprehension of digital media

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ju Hwan

    2008-11-15

    This book is divided four parts. The first part describes media and mark on sign and media, what is the sign?, interpretation of sign and semiotics. The second part is for production sign theory and origin of digital revolution such as the problem of origin of digital revolution, homogeneity of producing goods and sign : triple triangle model for production sign theory, triple triangle model for producing goods, triple triangle model of producing sign and triple triangle model of art works. The third parts deals with development of the media and meaning of digital revolution with four changes : invention of letter, appearance of printed media and establishment modernity, appearance electronic media and mess media and appearance of digital media. The last part mentions ontology of world wide web.

  15. NLM Digital Collections

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Library of Medicine's (NLM) Digital Collections offers a search-based Web service that provides access to the Dublin Core metadata and full-text OCR of...

  16. Digital subtraction angiography

    International Nuclear Information System (INIS)

    Neuwirth, J. Jr.; Bohutova, J.

    1987-01-01

    The quality of radiodiagnostic methods to a great extent depends on the quality of the resulting image. The basic technical principles are summed up of the different parts of digital subtraction angiography apparatus and of methods of improving the image. The instrument is based on a videochain consisting of an X-ray tube, an intensifier of the radiographic image, optical parts, a video camera, an analog-to-digital converter and a computer. The main advantage of the digitally processed image is the possibility of optimizing the image into a form which will contain the biggest amount of diagnostically valuable information. Described are the mathematical operations for improving the digital image: spatial filtration, pixel shift, time filtration, image integration, time interval differentation and matched filtering. (M.D.). 8 refs., 3 figs

  17. Digital imaging primer

    CERN Document Server

    Parkin, Alan

    2016-01-01

    Digital Imaging targets everyyone with an interest in digital imaging, be they professional or private, who uses even quite modest equipment such as a PC, digital camera and scanner, a graphics editor such as Paint, and an inkjet printer. Uniquely, it is intended to fill the gap between highly technical texts for academics (with access to expensive equipment) and superficial introductions for amateurs. The four-part treatment spans theory, technology, programs and practice. Theory covers integer arithmetic, additive and subtractive color, greyscales, computational geometry, and a new presentation of discrete Fourier analysis; Technology considers bitmap file structures, scanners, digital cameras, graphic editors, and inkjet printers; Programs develops several processing tools for use in conjunction with a standard Paint graphics editor and supplementary processing tools; Practice discusses 1-bit, greyscale, 4-bit, 8-bit, and 24-bit images for the practice section. Relevant QBASIC code is supplied an accompa...

  18. [Understanding chair-side digital technology for stomatology from an engineering viewpoint].

    Science.gov (United States)

    Zhao, Y J; Wang, Y

    2018-04-09

    In recent years with the rapid development of digital technology for stomatology, the application field, application model, technical features and technical connotation of the chair-side digital technology has got development and change. The open modular system has gradually replaced the traditional closed system, and the application field of digital technology is no longer limited to chair-side dental restoration, it also has been extend to various kinds of chair-side digital treatment-assisted technology. In this paper, from the engineering point of view, the up to date general connotation of chair-side digital technology was explained, the characteristics and the development of each unit in chair-side digital technology were analyzed, and the application pattern and the localization status were also discussed in this paper. The aim of this paper was to introduce the trend of chair-side digital technological to readers and to better guide clinical application.

  19. Institutionalizing Security Force Assistance

    National Research Council Canada - National Science Library

    Binetti, Michael R

    2008-01-01

    .... It looks at the manner in which security assistance guidance is developed and executed. An examination of national level policy and the guidance from senior military and civilian leaders highlights the important role of Security Force Assistance...

  20. ForeignAssistance.gov

    Data.gov (United States)

    US Agency for International Development — ForeignAssistance.gov provides a view of U.S. Government foreign assistance funds across agencies and enables users to explore, analyze, and review aid investments...

  1. Partnership for Prescription Assistance

    Science.gov (United States)

    ... may use our name without our permission. The Partnership for Prescription Assistance will help you find the ... Events Blog Facebook Twitter Start living better. The Partnership for Prescription Assistance helps qualifying patients without prescription ...

  2. Assisted delivery with forceps

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/patientinstructions/000509.htm Assisted delivery with forceps To use the sharing features on ... called vacuum assisted delivery . When is a Forceps Delivery Needed? Even after your cervix is fully dilated ( ...

  3. Vacuum-assisted delivery

    Science.gov (United States)

    ... medlineplus.gov/ency/patientinstructions/000514.htm Vacuum-assisted delivery To use the sharing features on this page, ... through the birth canal. When is Vacuum-assisted Delivery Needed? Even after your cervix is fully dilated ( ...

  4. Advanced digital optical communications

    CERN Document Server

    Binh, Le Nguyen

    2015-01-01

    This book provides a fundamental understanding of digital communication applications in optical communication technologies. Emphasizing operation principles versus mathematical analysis, the Second Edition includes new coverage of superchannel optical transmission systems, metropolitan and long-haul optical systems and networks, and Nyquist pulse shaping and high spectral efficiency of optical transmission systems, as well as new homework problems and examples. Featuring theoretical foundations as well as practical case studies, the text focuses on enhancements to digital technologies that are

  5. Digital Communication and Modulation

    DEFF Research Database (Denmark)

    Sørensen, John Aasted

    2010-01-01

    Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Spring 2010 Extent: 7.5 ects Class size: 9......Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Spring 2010 Extent: 7.5 ects Class size: 9...

  6. Digital Communication and Modulation

    DEFF Research Database (Denmark)

    Sørensen, John Aasted

    2010-01-01

    Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Autumn 2010 Extent: 7.5 ects Class size: 18......Fundamental principles in modern digital communication system like modems and wire- and wireless transmission over physical channels. Class room sessions and projects. Semester: Autumn 2010 Extent: 7.5 ects Class size: 18...

  7. Strategies in digital marketing

    OpenAIRE

    Robert DRAGOMIR; Mihai ANDRONIE

    2017-01-01

    The present paper deals with digital marketing. The approach into discussion is the strategies met with the concept mentioned above. Within the actual socio-economic context, the electronic equipments offer on one hand new and innovative methods for products promoting and, on the other hand new challenges for the consumers. Thus, we analysed different and major types of strategies, which have a great impact on the digital marketing.

  8. Science & Technology Digital Library

    OpenAIRE

    Solodovnik, Iryna

    2014-01-01

    This document contains information on the activities carried out within the project Science & Technology Digital Library and in particular, it describes the Metadata Core Reference Model. Metadata are strategic for semantic interoperability to and, from the repository. Metadata are essential for available and safe management of digital objects, and for their sustainability and preservation. For these reasons, the project needs to define a specific metadata model. The purpose of this document ...

  9. Introduction of digital control

    International Nuclear Information System (INIS)

    Kim, Sang Jin

    1988-01-01

    This book is one of mechatronics series. It deals with digital control, which includes what is digital control?, display way of control system, output of primary system, secondary system like example of system and display way of the system, stabilizing of control system such as method to decide stability and system out of control, displaying equation of state into vector, good control such as the right characteristic, transient behavior and design of position control system using DC servo motor.

  10. Digital academia: How higher education is affected by digital technology

    OpenAIRE

    Eriksmo, Anton; Sundberg, Johan

    2016-01-01

    Digital technology in higher education is constantly evolving. Understanding the effects of digital technology is important for higher education institutions in order to make good investments of digital technology. Previous research has focused on learning, teaching or the organization and the relation between one of these aspects and digital technology, thereby missing a broader understanding of how materiality in digital technology affects higher education. In this study themed interviews w...

  11. Digital Inheritance in the Netherlands

    NARCIS (Netherlands)

    Berlee, A.

    2017-01-01

    Our accumulation of assets is increasingly digital. What happens to these digital assets upon our death? In this Country Report, the topic of a digital inheritance is discussed in the context of Dutch law. It includes general rules on succession and their application to digital assets, which

  12. The Coevolution of Digital Ecosystems

    Science.gov (United States)

    SungYong, Um

    2016-01-01

    Digital ecosystems are one of the most important strategic issues in the current digital economy. Digital ecosystems are dynamic and generative. They evolve as new firms join and as heterogeneous systems are integrated into other systems. These features digital ecosystems determine economic and technological success in the competition among…

  13. Digital tomosynthesis of the breast

    International Nuclear Information System (INIS)

    Barkhausen, Joerg; Rody, Achim; Schaefer, Fritz K.W.

    2015-01-01

    The digital tomosynthesis applies the digital image analysis and 3D technology for improves diagnostic uses. The text book on the digital tomosynthesis of the breast covers the following issues: technique of tomosynthesis, clinical significance of digital breast tomosynthesis, innovations and future developments, case studies.

  14. Digital and analog communication systems

    Science.gov (United States)

    Shanmugam, K. S.

    1979-01-01

    The book presents an introductory treatment of digital and analog communication systems with emphasis on digital systems. Attention is given to the following topics: systems and signal analysis, random signal theory, information and channel capacity, baseband data transmission, analog signal transmission, noise in analog communication systems, digital carrier modulation schemes, error control coding, and the digital transmission of analog signals.

  15. Digital imaging in health care

    International Nuclear Information System (INIS)

    1987-01-01

    This volume describes equipment for the generation and processing of digital images in medicine. Separate chapters deal with international trade i this equipment, with economic and social considerations of digital imaging, with experiences in the use and production of digital imaging equipment and with the current status and likely trends in applications of digital imaging. 84 refs, figs and tabs

  16. Reference-Free CMOS Pipeline Analog-to-Digital Converters

    CERN Document Server

    Figueiredo, Michael; Evans, Guiomar

    2013-01-01

    This book shows that digitally assisted analog-to-digital converters are not the only way to cope with poor analog performance caused by technology scaling. It describes various analog design techniques that enhance the area and power efficiency without employing any type of digital calibration circuitry. These techniques consist of self-biasing for PVT enhancement, inverter-based design for improved speed/power ratio, gain-of-two obtained by voltage sum instead of charge redistribution, and current-mode reference shifting instead of voltage reference shifting. Together, these techniques allow enhancing the area and power efficiency of the main building blocks of a multiplying digital-to-analog converter (MDAC) based stage, namely, the flash quantizer, the amplifier, and the switched capacitor network of the MDAC. Complementing the theoretical analyses of the various techniques, a power efficient operational transconductance amplifier is implemented and experimentally characterized. Furthermore, a medium-low ...

  17. Digital communication constraints in prior space missions

    Science.gov (United States)

    Yassine, Nathan K.

    2004-01-01

    Digital communication is crucial for space endeavors. Jt transmits scientific and command data between earth stations and the spacecraft crew. It facilitates communications between astronauts, and provides live coverage during all phases of the mission. Digital communications provide ground stations and spacecraft crew precise data on the spacecraft position throughout the entire mission. Lessons learned from prior space missions are valuable for our new lunar and Mars missions set by our president s speech. These data will save our agency time and money, and set course our current developing technologies. Limitations on digital communications equipment pertaining mass, volume, data rate, frequency, antenna type and size, modulation, format, and power in the passed space missions are of particular interest. This activity is in support of ongoing communication architectural studies pertaining to robotic and human lunar exploration. The design capabilities and functionalities will depend on the space and power allocated for digital communication equipment. My contribution will be gathering these data, write a report, and present it to Communications Technology Division Staff. Antenna design is very carefully studied for each mission scenario. Currently, Phased array antennas are being developed for the lunar mission. Phased array antennas use little power, and electronically steer a beam instead of DC motors. There are 615 patches in the phased array antenna. These patches have to be modified to have high yield. 50 patches were created for testing. My part is to assist in the characterization of these patch antennas, and determine whether or not certain modifications to quartz micro-strip patch radiators result in a significant yield to warrant proceeding with repairs to the prototype 19 GHz ferroelectric reflect-array antenna. This work requires learning how to calibrate an automatic network, and mounting and testing antennas in coaxial fixtures. The purpose of this

  18. Fast-track video-assisted thoracoscopic surgery

    DEFF Research Database (Denmark)

    Holbek, Bo Laksafoss; Petersen, René Horsleben; Kehlet, Henrik

    2016-01-01

    Objectives To provide a short overview of fast-track video-assisted thoracoscopic surgery (VATS) and to identify areas requiring further research. Design A literature search was made using key words including: fast-track, enhanced recovery, video-assisted thoracoscopic surgery, robot......-assisted thoracoscopic surgery (RATS), robotic, thoracotomy, single-incision, uniportal, natural orifice transluminal endoscopic surgery (NOTES), chest tube, air-leak, digital drainage, pain management, analgesia, perioperative management, anaesthesia and non-intubated. References from articles were screened for further...

  19. Feeding assistive robotics, socio-technological imaginaries and care

    DEFF Research Database (Denmark)

    Nickelsen, Niels Christian Mossfeldt

    The media and political/managerial levels focus on the opportunities to re-perform Denmark through digitization. Feeding assistive robotics is a welfare technology, relevant to citizens with low or no function in their arms. Despite national dissemination strategies, it proves difficult to recruit...

  20. Socio-technological imaginaries, assistive robotics and transformation of care

    DEFF Research Database (Denmark)

    Nickelsen, Niels Christian Mossfeldt

    The media and political/managerial levels focus on the opportunities to re-perform Denmark through digitization. Feeding assistive robotics (FAR) is a welfare technology, relevant to citizens with no function in their arms. Despite national dissemination strategies, it proves difficult to recruit...