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Sample records for diffusion coefficient measurements

  1. Measurement of chemical diffusion coefficients in liquid binary alloys

    International Nuclear Information System (INIS)

    Keita, M.; Steinemann, S.; Kuenzi, H.U.

    1976-01-01

    New measurements of the chemical diffusion coefficient in liquid binary alloys are presented. The wellknown geometry of the 'capillary-reservoir' is used and the concentration is obtained from a resistivity measurement. The method allows to follow continuously the diffusion process in the liquid state. A precision of at least 10% in the diffusion coefficient is obtained with a reproductibility better than 5%. The systems Hg-In, Al-Sn, Al-Si have been studied. Diffusion coefficients are obtained as a function of temperature, concentration, and geometrical factors related to the capillary (diameter, relative orientation of density gradient and gravity). (orig.) [de

  2. Local carbon diffusion coefficient measurement in the S-1 spheromak

    International Nuclear Information System (INIS)

    Mayo, R.M.; Levinton, F.M.; Meyerhofer, D.D.; Chu, T.K.; Paul, S.F.; Yamada, M.

    1988-10-01

    The local carbon diffusion coefficient was measured in the S - 1 spheromak by detecting the radial spread of injected carbon impurity. The radial impurity density profile is determined by the balance of ionization and diffusion. Using measured local electron temperature T/sub e/ and density n/sub e/, the ionization rate is determined from which the particle diffusion coefficient is inferred. The results found in this work are consistent with Bohm diffusion. The absolute magnitude of D/sub /perpendicular// was determined to be (4/approximately/6) /times/ D/sub Bohm/. 25 refs., 13 figs., 2 tabs

  3. Comparison of field-measured radon diffusion coefficients with laboratory-measured coefficients

    International Nuclear Information System (INIS)

    Lepel, E.A.; Silker, W.B.; Thomas, V.W.; Kalkwarf, D.R.

    1983-04-01

    Experiments were conducted to compare radon diffusion coefficients determined for 0.1-m depths of soils by a steady-state method in the laboratory and diffusion coefficients evaluated from radon fluxes through several-fold greater depths of the same soils covering uranium-mill tailings. The coefficients referred to diffusion in the total pore volume of the soils and are equivalent to values for the quantity, D/P, in the Generic Environmental Impact Statement on Uranium Milling prepared by the US Nuclear Regulatory Commission. Two soils were tested: a well-graded sand and an inorganic clay of low plasticity. For the flux evaluations, radon was collected by adsorption on charcoal following passive diffusion from the soil surface and also from air recirculating through an aluminum tent over the soil surface. An analysis of variance in the flux evaluations showed no significant difference between these two collection methods. Radon diffusion coefficients evaluated from field data were statistically indistinguishable, at the 95% confidence level, from those measured in the laboratory; however, the low precision of the field data prevented a sensitive validation of the laboratory measurements. From the field data, the coefficients were calculated to be 0.03 +- 0.03 cm 2 /s for the sand cover and 0.0036 +- 0.0004 cm 2 /s for the clay cover. The low precision in the coefficients evaluated from field data was attributed to high variation in radon flux with time and surface location at the field site

  4. Apparent diffusion coefficient measurements in progressive supranuclear palsy

    Energy Technology Data Exchange (ETDEWEB)

    Ohshita, T.; Oka, M.; Imon, Y.; Yamaguchi, S.; Mimori, Y.; Nakamura, S. [Hiroshima Univ. (Japan). School of Medicine

    2000-09-01

    We measured the apparent diffusion coefficient (ADC), using diffusion-weighted imaging (DWI) and signal intensity on T2-weighted MRI in the cerebral white matter of patients with progressive supranuclear palsy (PSP) and age-matched normal subjects. In PSP, ADC in the prefrontal and precentral white matter was significantly higher than in controls. There was no significant difference in signal intensity on T2-weighted images. The ADC did correlate with signal intensity. The distribution of the elevation of ADC may be the consequence of underlying pathological changes, such as neurofibrillary tangles or glial fibrillary tangles in the cortex. Our findings suggest that ADC measurement might be useful for demonstrating subtle neuropathological changes. (orig.)

  5. Comparison of radon diffusion coefficients measured by transient-diffusion and steady-state laboratory methods

    International Nuclear Information System (INIS)

    Kalwarf, D.R.; Nielson, K.K.; Rich, D.C.; Rogers, V.C.

    1982-11-01

    A method was developed and used to determine radon diffusion coefficients in compacted soils by transient-diffusion measurements. A relative standard deviation of 12% was observed in repeated measurements with a dry soil by the transient-diffusion method, and a 40% uncertainty was determined for moistures exceeding 50% of saturation. Excellent agreement was also obtained between values of the diffusion coefficient for radon in air, as measured by the transient-diffusion method, and those in the published literature. Good agreement was also obtained with diffusion coefficients measured by a steady-state method on the same soils. The agreement was best at low moistures, averaging less than ten percent difference, but differences of up to a factor of two were observed at high moistures. The comparison of the transient-diffusion and steady-state methods at low moistures provides an excellent verification of the theoretical validity and technical accuracy of these approaches, which are based on completely independent experimental conditions, measurement methods and mathematical interpretations

  6. Unsaturated soil moisture drying and wetting diffusion coefficient measurements in the laboratory.

    Science.gov (United States)

    2009-09-01

    ABSTRACTTransient moisture flow in an unsaturated soil in response to suction changes is controlled by the unsaturated moisture diffusion coefficient. The moisture diffusion coefficient can be determined by measuring suction profiles over time. The l...

  7. Effective diffusion coefficient of radon in concrete, theory and method for field measurements

    International Nuclear Information System (INIS)

    Culot, M.V.J.; Olson, H.G.; Schiager, K.J.

    1976-01-01

    A linear diffusion model serves as the basis for determination of an effective radon diffusion coefficient in concrete. The coefficient was needed to later allow quantitative prediction of radon accumulation within and behind concrete walls after application of an impervious radon barrier. A resolution of certain discrepancies noted in the literature in the use of an effective diffusion coefficient to model diffusion of a radioactive gas through a porous medium is suggested. An outline of factors expected to affect the concrete physical structure and the effective diffusion coefficient of radon through it is also presented. Finally, a field method for evaluating effective radon diffusion coefficients in concrete is proposed and results of measurements performed on a concrete foundation wall are compared with similar published values of gas diffusion coefficients in concrete. (author)

  8. Measurements of the Fe3+ diffusion coefficient in Fricke Xylenol gel using optical density measurements

    International Nuclear Information System (INIS)

    Nonato de Oliveira, Lucas; Sampaio, Francisco Glaildo Almeida; Moreira, Marcos Vasques; Almeida, Adelaide de

    2014-01-01

    In Fricke dosimetry, optical density measurements are performed some time after dosimeter irradiation. Values of the diffusion coefficient of Fe 3+ in Fricke Xylenol gel (FXG) are necessary for determining the spatial distribution of the absorbed dose from measurements of the optical density. Five sets of FXG dosimeters, kept at different constant temperatures, were exposed to collimated 6 MV photons. The optical density profile, proportional to the Fe 3+ concentration, at the boundary between irradiated and non-irradiated parts of each dosimeter was measured periodically over a period of 60 h. By comparing the experimental data with a function that accounts for the unobserved initial concentration profile of Fe 3+ in the FXG, we obtained diffusion coefficients 0.30±0.05, 0.40±0.05, 0.50±0.05, 0.60±0.05 and 0.80±0.05 mm 2 /h for the temperatures 283.0±0.5, 286.0±0.5, 289.0±0.5, 292.0±0.5, and 296.0±0.5 K, respectively. The activation energy of Fe 3+ diffusion in the gel, 0.54±0.06 eV, was determined from the temperature dependence of the diffusion coefficients. - Highlights: • A new analytical method to determine diffusion coefficients of ions in gels is proposed. • The method is applied for measurements of the diffusion coefficients of Fe 3+ ions in a Fricke gel dosimeter. • Activation energy of the Fe 3+ ions in the gel was found to be 0.54 ±0.06 eV

  9. Separate measurement of local diffusion coefficients in grain boundaries and in adjacent regions

    International Nuclear Information System (INIS)

    Klotsman, S.M.; Kajgorodov, V.N.

    1994-01-01

    A new measuring technique is presented that allows one separate determination of grain boundary width and local diffusion coefficients. With the use of the technique presented phenomenological description is accompished for time and temperature dependences of relative and absolute level populations in a zone of preferential intercrystalline diffusion. Local diffusion coefficients obtained for the upper temperature limit of applicability of the technique proposed are in a good agreement with values calculated form coordinate distribution of atoic probes. Local diffusion coefficients determined at lower temperatures essentially differ from those calculated assuming that suction coefficient is equal to a coefficient of volume diffusion. Experimental dta are given for diffusion parameters in Ag, Pd and W polycrystals. 16 refs., 3 figs., 2 tabs

  10. Measurement of the apparent diffusion coefficient in paediatric mitochondrial encephalopathy cases and a comparison of parenchymal changes associated with the disease using follow-up diffusion coefficient measurements

    Energy Technology Data Exchange (ETDEWEB)

    Uysal, Fatma, E-mail: afatmauysal@gmail.com [Dokuz Eylül University, Department of Pediatric Radiology, Izmir (Turkey); Çakmakçı, Handan, E-mail: handan.cakmakci@deu.edu.tr [Dokuz Eylül University, Department of Pediatric Radiology, Izmir (Turkey); Yiş, Uluç, E-mail: ulucyis@deu.edu.tr [Dokuz Eylül University, Department of Pediatric Neurology, Izmir (Turkey); Ellidokuz, Hülya, E-mail: hulyaellidokuz@deu.edu.tr [Dokuz Eylül University, Department of Medical Statistics, Izmir (Turkey); Hız, Ayşe Semra, E-mail: aysesemrahiz@deu.edu.tr [Dokuz Eylül University, Department of Pediatric Neurology, Izmir (Turkey)

    2014-01-15

    Objectives: To reveal the contribution of MRI and diffusion-weighted imaging (DWI) to the diagnosis of mitochondrial encephalopathy (ME) and to evaluate the parenchymal changes associated with this disease in the involved parenchymal areas using the apparent diffusion coefficient (ADC) parameter. Methods: Ten patients who had undergone MRI and DWI analysis with a pre-diagnosis of neurometabolic disease, and who were subsequently diagnosed with ME in laboratory and/or genetic studies, were included in our study. ADC values were compared with a control group composed of 20 patients of similar age with normal brains. Evaluations involved measurements made in 20 different areas determined on the ADC map. The dominance or contribution of ADC coefficient measurements to the conventional sequences was compared with the controls. Results: In the first examination, an increase in both diffusion and ADC values was detected in six cases and diffusion restriction and a decrease in ADC values in three patients. While an increase in both diffusion and ADC values was demonstrated in four cases, there was diffusion restriction and a decrease in ADC values in three cases in the control examinations. Conclusions: DWI provides information that complements conventional MRI sequences in the diagnosis of ME.

  11. Exciton diffusion coefficient measurement in ZnO nanowires under electron beam irradiation

    Science.gov (United States)

    Donatini, Fabrice; Pernot, Julien

    2018-03-01

    In semiconductor nanowires (NWs) the exciton diffusion coefficient can be determined using a scanning electron microscope fitted with a cathodoluminescence system. High spatial and temporal resolution cathodoluminescence experiments are needed to measure independently the exciton diffusion length and lifetime in single NWs. However, both diffusion length and lifetime can be affected by the electron beam bombardment during observation and measurement. Thus, in this work the exciton lifetime in a ZnO NW is measured versus the electron beam dose (EBD) via a time-resolved cathodoluminescence experiment with a temporal resolution of 50 ps. The behavior of the measured exciton lifetime is consistent with our recent work on the EBD dependence of the exciton diffusion length in similar NWs investigated under comparable SEM conditions. Combining the two results, the exciton diffusion coefficient in ZnO is determined at room temperature and is found constant over the full span of EBD.

  12. Rapid yet accurate measurement of mass diffusion coefficients by phase shifting interferometer

    CERN Document Server

    Guo Zhi Xiong; Komiya, A

    1999-01-01

    The technique of using a phase-shifting interferometer is applied to the study of diffusion in transparent liquid mixtures. A quick method is proposed for determining the diffusion coefficient from the measurements of the location of fringes on a grey level picture. The measurement time is very short (within 100 s) and a very small transient diffusion field can be observed and recorded accurately with a rate of 30 frames per second. The measurement can be completed using less than 0.12 cc of solutions. The influence of gravity on the measurement of the diffusion coefficient is eliminated in the present method. Results on NaCl-water diffusion systems are presented and compared with the reference data. (author)

  13. Procedures and apparatus for measuring diffusion and distribution coefficients in compacted clays

    Energy Technology Data Exchange (ETDEWEB)

    Hume, H B

    1993-12-01

    Diffusion and distribution coefficients are needed to assess the migration of radionuclides through the compacted clay-based buffer and backfill materials proposed for use in a nuclear fuel waste disposal vault. This report describes the techniques used to measure these coefficients. Both steady-state and transient diffusion experiments are discussed. The procedures used to prepare the clay plug, assemble the cell, conduct the experiment and calculate the results are described. In addition, methods for obtaining distribution coefficients for radionuclides on both loose and compacted clays are discussed. (author). 18 refs., 3 tabs., 16 figs.

  14. Procedures and apparatus for measuring diffusion and distribution coefficients in compacted clays

    International Nuclear Information System (INIS)

    Hume, H.B.

    1993-12-01

    Diffusion and distribution coefficients are needed to assess the migration of radionuclides through the compacted clay-based buffer and backfill materials proposed for use in a nuclear fuel waste disposal vault. This report describes the techniques used to measure these coefficients. Both steady-state and transient diffusion experiments are discussed. The procedures used to prepare the clay plug, assemble the cell, conduct the experiment and calculate the results are described. In addition, methods for obtaining distribution coefficients for radionuclides on both loose and compacted clays are discussed. (author). 18 refs., 3 tabs., 16 figs

  15. New sensitive micro-measurements of dynamic surface tension and diffusion coefficients

    DEFF Research Database (Denmark)

    Kinoshita, Koji; Ortiz, Elisa Parra; Needham, David

    2017-01-01

    Currently available dynamic surface tension (DST) measurement methods, such as Wilhelmy plate, droplet- or bubble-based methods, still have various experimental limitations such as the large size of the interface, convection in the solution, or a certain “dead time” at initial measurement....... These limitations create inconsistencies for the kinetic analysis of surfactant adsorption/desorption, especially significant for ionic surfactants. Here, the “micropipette interfacial area-expansion method” was introduced and validated as a new DST measurement having a high enough sensitivity to detect diffusion...... for surface excess concentration. We found that the measured diffusion coefficient of 1-Octanol, 7.2 ± 0.8 × 10−6 cm2/s, showed excellent agreement with the result from an alternative method, “single microdroplet catching method”, to measure the diffusion coefficient from diffusion-controlled microdroplet...

  16. Interaction between lactose and cadmium chloride in aqueous solutions as seen by diffusion coefficients measurements

    International Nuclear Information System (INIS)

    Verissimo, Luis M.P.; Gomes, Joselaine C.S.; Romero, Carmen; Esteso, Miguel A.; Sobral, Abilio J.F.N.; Ribeiro, Ana C.F.

    2013-01-01

    Highlights: ► Diffusion coefficients of aqueous systems containing lactose and cadmium chloride. ► Influence of the lactose on the diffusion of cadmium chloride. ► Interactions between Cd 2+ and lactose. -- Abstract: Diffusion coefficients of an aqueous system containing cadmium chloride 0.100 mol · dm −3 and lactose at different concentrations at 25 °C have been measured, using a conductimetric cell and an automatic apparatus to follow diffusion. The cell relies on an open-ended capillary method and a conductimetric technique is used to follow the diffusion process by measuring the resistance of a solution inside the capillaries, at recorded times. From these results and by ab initio calculations, it was possible to obtain a better understanding of the effect of lactose on transport of cadmium chloride in aqueous solutions

  17. Estimation of the thermal diffusion coefficient in fusion plasmas taking frequency measurement uncertainties into account

    International Nuclear Information System (INIS)

    Van Berkel, M; Hogeweij, G M D; Van den Brand, H; De Baar, M R; Zwart, H J; Vandersteen, G

    2014-01-01

    In this paper, the estimation of the thermal diffusivity from perturbative experiments in fusion plasmas is discussed. The measurements used to estimate the thermal diffusivity suffer from stochastic noise. Accurate estimation of the thermal diffusivity should take this into account. It will be shown that formulas found in the literature often result in a thermal diffusivity that has a bias (a difference between the estimated value and the actual value that remains even if more measurements are added) or have an unnecessarily large uncertainty. This will be shown by modeling a plasma using only diffusion as heat transport mechanism and measurement noise based on ASDEX Upgrade measurements. The Fourier coefficients of a temperature perturbation will exhibit noise from the circular complex normal distribution (CCND). Based on Fourier coefficients distributed according to a CCND, it is shown that the resulting probability density function of the thermal diffusivity is an inverse non-central chi-squared distribution. The thermal diffusivity that is found by sampling this distribution will always be biased, and averaging of multiple estimated diffusivities will not necessarily improve the estimation. Confidence bounds are constructed to illustrate the uncertainty in the diffusivity using several formulas that are equivalent in the noiseless case. Finally, a different method of averaging, that reduces the uncertainty significantly, is suggested. The methodology is also extended to the case where damping is included, and it is explained how to include the cylindrical geometry. (paper)

  18. DCCO and SCCO: measurements of diffusion coefficients and of thermodiffusion in microgravity; DCCO et SCCO: mesures de coefficients de diffusion et de thermodiffusion en microgravite

    Energy Technology Data Exchange (ETDEWEB)

    Legros, J.C.; Van Vaerenbergh, S.; Dubois, F.; Decroly, Y. [Universite Libre de Bruxelles (Belgium); Montel, F. [ELF-Aquitaine Production, 64 - Pau (France); Goodman, S. [C-CORE, New Foundland, (Canada); Bekaert, G. [SABCA, Bruxelles (Belgium); Van Ransbeek, E. [IASB-BIRA, Bruxelles (Belgium)

    1996-12-31

    Measurements of diffusion coefficients of ternary systems and of thermodiffusion coefficients of multicomponent systems, including crude oils, have been undertaken by MRC and Elf-Aquitaine. The experiments DCCO and SCCO (respectively Diffusion and Soret Coefficients of Crude Oils) will be performed in 1997 and 1998 in GAS containers on the Space Shuttle. The 9 systems of DCCO are analyzed by Mach-Zehnder bicolor interferometry. The samples of the 18 systems of SCCO, among which three at 300 bars and at a mean temperature of 60 deg. C, will be analyzed after recovery on ground by a chromatographic technique. Such measurements performed in microgravity, like the measurements of Soret coefficients of binary solutions performed in the microgravity SCM experiments, are necessary reference measurements. (authors) 12 refs.

  19. Diffusion weighted imaging and estimation of prognosis using apparent diffusion coefficient measurements in ischemic stroke

    Energy Technology Data Exchange (ETDEWEB)

    Gonen, Korcan Aysun, E-mail: aysunbalc@yahoo.com [Department of Radiology, State Hospital, Eski Cami district, Hastane street, N:1, 59300, Tekirdag (Turkey); Simsek, Mehmet Masum, E-mail: radyoloji@haydapasanumune.gov.tr [Department of Radiology, Haydarpasa Numune Training and Research Hospital, Tibbiye street, Uskudar 34200, Istanbul (Turkey)

    2010-11-15

    Objective: Estimation of the prognosis of infarction by using diffusion weighted imaging (DWI) and quantitative apparent diffusion coefficient (ADC) measurements. Methods: 23 patients having acute stroke symptoms with verified infarction in magnetic resonance imaging (MRI) were included in this study. Their MRI studies were performed between 6 and 12 h after the onset of their symptoms and were repeated on the fifth day. The infarction volumes were calculated by using DWI and the patients were divided into two groups as the ones having an expansion in the infarction area (group 1, n = 16) and the others having no expansion in the infarction area (group 2, n = 7). Quantitative ADC values were estimated. The groups were compared in terms of the ADC values on ADC maps obtained from DWI, performed during the between 6 and 12 h from the onset of the symptoms, referring to the core of the infarction (ADC{sub IC}), ischemic penumbra (ADC{sub P}) and the nonischemic parenchymal tissue (ADC{sub N}). P values < 0.05 were accepted to be statistically significant. Results: During the between 6 and 12 h mean infarction volume calculated by DWI was 23.3 cm{sup 3} for group 1 patients (ranging from 1.1 to 68.6) and this was found to be 40.3 cm{sup 3} (ranging from 1.8 to 91.5) on the fifth day. For the group 2 patients these values were found to be 42.1 cm{sup 3} (ranging from 1 to 94.7) and 41.9 (ranging from 1 to 94.7) for the same intervals respectively. A significant statistical result was failed to be demonstrated between the mean ADC{sub IC} and ADC{sub N} values (p = 0.350 and p = 0.229 respectively). However the comparison of the ADC{sub P} values between the groups was found to be highly significant (p < 0.001). When the differences between the ADC{sub P} and ADC{sub IC} and ADC{sub N} and ADC{sub P} were compared the results proved to be statistically significant (p = 0.038 and p < 0.001 respectively). Conclusions: We believe that ADC results that would be obtained from

  20. Diffusion weighted imaging and estimation of prognosis using apparent diffusion coefficient measurements in ischemic stroke

    International Nuclear Information System (INIS)

    Gonen, Korcan Aysun; Simsek, Mehmet Masum

    2010-01-01

    Objective: Estimation of the prognosis of infarction by using diffusion weighted imaging (DWI) and quantitative apparent diffusion coefficient (ADC) measurements. Methods: 23 patients having acute stroke symptoms with verified infarction in magnetic resonance imaging (MRI) were included in this study. Their MRI studies were performed between 6 and 12 h after the onset of their symptoms and were repeated on the fifth day. The infarction volumes were calculated by using DWI and the patients were divided into two groups as the ones having an expansion in the infarction area (group 1, n = 16) and the others having no expansion in the infarction area (group 2, n = 7). Quantitative ADC values were estimated. The groups were compared in terms of the ADC values on ADC maps obtained from DWI, performed during the between 6 and 12 h from the onset of the symptoms, referring to the core of the infarction (ADC IC ), ischemic penumbra (ADC P ) and the nonischemic parenchymal tissue (ADC N ). P values 3 for group 1 patients (ranging from 1.1 to 68.6) and this was found to be 40.3 cm 3 (ranging from 1.8 to 91.5) on the fifth day. For the group 2 patients these values were found to be 42.1 cm 3 (ranging from 1 to 94.7) and 41.9 (ranging from 1 to 94.7) for the same intervals respectively. A significant statistical result was failed to be demonstrated between the mean ADC IC and ADC N values (p = 0.350 and p = 0.229 respectively). However the comparison of the ADC P values between the groups was found to be highly significant (p P and ADC IC and ADC N and ADC P were compared the results proved to be statistically significant (p = 0.038 and p < 0.001 respectively). Conclusions: We believe that ADC results that would be obtained from the core and the penumbra of the infarction area will be beneficial in the estimation of the infarction prognosis and in the planning of a treatment protocol.

  1. Measurement of the local particle diffusion coefficient in a magnetized plasma

    International Nuclear Information System (INIS)

    Meyerhofer, D.D.; Levinton, F.M.

    1987-02-01

    Local impurity particle diffusion coefficients have been measured in a low temperature plasma by the injection of test particles at the center of the plasma. The injection is accomplished by a high voltage discharge between two small graphite electrodes on a probe. The probe can be located anywhere in the plasma. The diffusion is observed spectroscopically. An analysis of the spatial and temporal evolution of the CII radiation from the carbon discharge can determine the parallel and perpendicular diffusion of the impurity ions. Results with the diagnostic have been obtained in the Proto S-1/C spheromak. The measured value of the diffusion coefficient in the afterglow plasma is in good agreement with classical predictions

  2. Interferometric measurement of a diffusion coefficient: comparison of two methods and uncertainty analysis

    International Nuclear Information System (INIS)

    Riquelme, Rodrigo; Lira, Ignacio; Perez-Lopez, Carlos; Rayas, Juan A; RodrIguez-Vera, Ramon

    2007-01-01

    Two methods to measure the diffusion coefficient of a species in a liquid by optical interferometry were compared. The methods were tested on a 1.75 M NaCl aqueous solution diffusing into water at 26 deg. C. Results were D = 1.587 x 10 -9 m 2 s -1 with the first method and D = 1.602 x 10 -9 m 2 s -1 with the second method. Monte Carlo simulation was used to assess the possible dispersion of these results. The standard uncertainties were found to be of the order of 0.05 x 10 -9 m 2 s -1 with both methods. We found that the value of the diffusion coefficient obtained by either method is very sensitive to the magnification of the optical system, and that if diffusion is slow the measurement of time does not need to be very accurate

  3. Combined measurement of surface, grain boundary and lattice diffusion coefficients on olivine bi-crystals

    Science.gov (United States)

    Marquardt, Katharina; Dohmen, Ralf; Wagner, Johannes

    2014-05-01

    Diffusion along interface and grain boundaries provides an efficient pathway and may control chemical transport in rocks as well as their mechanical strength. Besides the significant relevance of these diffusion processes for various geologic processes, experimental data are still very limited (e.g., Dohmen & Milke, 2010). Most of these data were measured using polycrystalline materials and the formalism of LeClaire (1951) to fit integrated concentration depth profiles. To correctly apply this formalism, certain boundary conditions of the diffusion problem need to be fulfilled, e.g., surface diffusion is ignored, and furthermore the lattice diffusion coefficient has to be known from other studies or is an additional fitting parameter, which produces some ambiguity in the derived grain boundary diffusion coefficients. We developed an experimental setup where we can measure the lattice and grain boundary diffusion coefficients simultaneously but independent and demonstrate the relevance of surface diffusion for typical grain boundary diffusion experiments. We performed Mg2SiO4 bicrystal diffusion experiments, where a single grain boundary is covered by a thin-film of pure Ni2SiO4 acting as diffusant source, produced by pulsed laser deposition. The investigated grain boundary is a 60° (011)/[100]. This specific grain boundary configuration was modeled using molecular dynamics for comparison with the experimental observations in the transmission electron microscope (TEM). Both, experiment and model are in good agreement regarding the misorientation, whereas there are still some disagreements regarding the strain fields along the grain boundary that are of outmost importance for the strengths of the material. The subsequent diffusion experiments were carried out in the temperature range between 800° and 1450° C. The inter diffusion profiles were measured using the TEMs energy dispersive x-ray spectrometer standardized using the Cliff-Lorimer equation and EMPA

  4. A method to measure the diffusion coefficient by neutron wave propagation for limited samples

    International Nuclear Information System (INIS)

    Woznicka, U.

    1986-03-01

    A study has been made of the use of the neutron wave and pulse propagation method for measurement of thermal neutron diffusion parameters. Earlier works an homogenous and heterogeneous media are reviewed. A new method is sketched for the determination of the diffusion coefficient for samples of limited size. The principle is to place a relatively thin slab of the material between two blocks of a medium with known properties. The advantages and disadvantages of the method are discussed. (author)

  5. Noninvasive photoacoustic measurement of absorption coefficient using internal light irradiation of cylindrical diffusing fiber

    Science.gov (United States)

    Peng, Dong-qing; Zhu, Li-li; Li, Zhi-fang; Li, Hui

    2017-09-01

    Absorption coefficient of biological tissue is an important parameter in biomedicine, but its determination remains a challenge. In this paper, we propose a method using focusing photoacoustic imaging technique and internal light irradiation of cylindrical diffusing fiber (CDF) to quantify the target optical absorption coefficient. Absorption coefficients for ink absorbers are firstly determined through photoacoustic and spectrophotometric measurements at the same excitation, which demonstrates the feasibility of this method. Also, the optical absorption coefficients of ink absorbers with several concentrations are measured. Finally, the two-dimensional scanning photoacoustic image is obtained. Optical absorption coefficient measurement and simultaneous photoacoustic imaging of absorber non-invasively are the typical characteristics of the method. This method can play a significant role for non-invasive determination of blood oxygen saturation, the absorption-based imaging and therapy.

  6. Measurement of molecular diffusion coefficients of carbon dioxide and methane in heavy oil

    Energy Technology Data Exchange (ETDEWEB)

    Gu, Y.; Tharanivasan, A.K.; Yang, C. [Regina Univ., SK (Canada)

    2004-07-01

    Vapour extraction (VAPEX) is a solvent-based thermal recovery process which is considered to be a viable process for recovering heavy oil. In order to develop a solvent-based enhanced oil recovery (EOR) operation, it is necessary to know the rate and extent of oil mobilization by the solvent. The molecular diffusion coefficient of solvent gas in heavy oil must be known. In this study, the pressure decay method was used to measure the molecular diffusivity of a gas solvent in heavy oil by monitoring the decaying pressure. The pressure decay method is a non-intrusive method in which physical contact is made between the gas solvent and the heavy oil. The pressure versus time data are measured until the heavy oil reaches complete saturation. The diffusion coefficient can be determined from the measured data and a mathematical model. In this study, the molecular diffusion coefficients of carbon dioxide-heavy oil and methane-heavy oil systems were measured and compared. The experiments were performed in closed high-pressure cells at constant reservoir temperature. An analytical solution was also obtained to predict the pressure in the gas phase and for the boundary conditions at the solvent-heavy oil interface for each solvent. Solvent diffusivity was determined by finding the best match of the numerically predicted and experimentally measured pressures.

  7. Comparison of measured and satellite-derived spectral diffuse attenuation coefficients for the Arabian Sea

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, T.; Talaulikar, M.; Desa, E.; Matondkar, S.G.P.; Mascarenhas, A.

    The results of study comparing the spectral diffuse attenuation coefficients Kd(Lambda) measured in the Arabian Sea with those derived from the Sea-Viewing Wide Field-of-View Sensor (SeaWiFS) using three algorithms, of which two are empirical...

  8. Permeability and Diffusion Coefficients of Single Methyl Lactate Enantiomers in Nafion® and Cellophane Membranes Measured in Diffusion Cell.

    Czech Academy of Sciences Publication Activity Database

    Hovorka, Š.; Randová, A.; Borbášová, T.; Sysel, P.; Vychodilová, Hana; Červenková Šťastná, Lucie; Brožová, Libuše; Žitka, Jan; Storch, Jan; Kačírková, Marie; Drašar, P.; Izák, Pavel

    2016-01-01

    Roč. 158, JAN 28 (2016), s. 322-332 ISSN 1383-5866 R&D Projects: GA ČR(CZ) GAP106/12/0569 Institutional support: RVO:67985858 ; RVO:61389013 Keywords : diffusion coefficient measurement * permeability * nafion * cellophane * chirality of polymer membrane Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 3.359, year: 2016

  9. Measurements of the diffusion and reflection coefficients of Cd(1S0) in noble gases

    International Nuclear Information System (INIS)

    Rudecki, P.; Domyslawska, J.

    2003-01-01

    A new method of simultaneous determining of the diffusion coefficient and the reflection coefficient of atoms from the reservoir walls is presented. The diffusion coefficient of cadmium atoms in the ground state in buffer noble gas atoms such as Ne, Ar, Kr and Xe and reflection coefficient of Cd atoms from the quartz cell wall in the temperature range 350-550 K were determined. Experimental values diffusion coefficient are compared with theoretical ones calculated from a available potentials. (author)

  10. Analysis and correction of gradient nonlinearity bias in apparent diffusion coefficient measurements.

    Science.gov (United States)

    Malyarenko, Dariya I; Ross, Brian D; Chenevert, Thomas L

    2014-03-01

    Gradient nonlinearity of MRI systems leads to spatially dependent b-values and consequently high non-uniformity errors (10-20%) in apparent diffusion coefficient (ADC) measurements over clinically relevant field-of-views. This work seeks practical correction procedure that effectively reduces observed ADC bias for media of arbitrary anisotropy in the fewest measurements. All-inclusive bias analysis considers spatial and time-domain cross-terms for diffusion and imaging gradients. The proposed correction is based on rotation of the gradient nonlinearity tensor into the diffusion gradient frame where spatial bias of b-matrix can be approximated by its Euclidean norm. Correction efficiency of the proposed procedure is numerically evaluated for a range of model diffusion tensor anisotropies and orientations. Spatial dependence of nonlinearity correction terms accounts for the bulk (75-95%) of ADC bias for FA = 0.3-0.9. Residual ADC non-uniformity errors are amplified for anisotropic diffusion. This approximation obviates need for full diffusion tensor measurement and diagonalization to derive a corrected ADC. Practical scenarios are outlined for implementation of the correction on clinical MRI systems. The proposed simplified correction algorithm appears sufficient to control ADC non-uniformity errors in clinical studies using three orthogonal diffusion measurements. The most efficient reduction of ADC bias for anisotropic medium is achieved with non-lab-based diffusion gradients. Copyright © 2013 Wiley Periodicals, Inc.

  11. Evaluation of Systematic and Random Error in the Measurement of Equilibrium Solubility and Diffusion Coefficient for Liquids in Polymers

    National Research Council Canada - National Science Library

    Shuely, Wendel

    2001-01-01

    A standardized thermogravimetric analyzer (TGA) desorption method for measuring the equilibrium solubility and diffusion coefficient of toxic contaminants with polymers was further developed and evaluated...

  12. Experimental Determination of Drug Diffusion Coefficients in Unstirred Aqueous Environments by Temporally Resolved Concentration Measurements

    DEFF Research Database (Denmark)

    Di Cagno, Massimiliano Pio; Clarelli, Fabrizio; Vabenø, Jon

    2018-01-01

    or the need for dedicated instrumentation. In this work, a simple but reliable method based on time resolved concentration measurements by UV-visible spectroscopy in an unstirred aqueous environment was developed. This method is based on spectroscopic measurement of the variation of the local concentration...... characteristics (i.e. ionic strength and presence of complexing agents) on the diffusivity. The method can be employed in any research laboratory equipped with a standard UV-visible spectrophotometer, and could become a useful and straightforward tool in order to characterize diffusion coefficients...

  13. Drift tube measurements of mobilities and longitudinal diffusion coefficients of ions in gases

    International Nuclear Information System (INIS)

    Chelf, R.D.

    1982-01-01

    The zero-field mobilities of Br - and NH 4+ in O 2 were determined as a function of gas temperature in a high pressure drift tube mass spectrometer. The mobilities and longitudinal diffusion coefficients of the ion-gas combinations Br - in Ne and Kr, Li + in Xe, and Tl/ + in Kr and Xe were determined as a function of E/N, where E is the electric field strength and N is the gas number density in a low pressure drift tube mass spectrometer. The measured longitudinal diffusion coefficients were used for a test and comparison of the generalized Einstein relations of Viehland-Mason and Waldman-Mason theories. The measured mobilities of Br - in Kr and Tl/ + in Kr were used in an iterative-inversion scheme from which the ion-neutral interaction potentials were determined

  14. IN-SITU MEASURING METHOD OF RADON AND THORON DIFFUSION COEFFICIENT IN SOIL

    Directory of Open Access Journals (Sweden)

    V.S. Yakovleva

    2014-06-01

    Full Text Available A simple and valid in-situ measurement method of effective diffusion coefficient of radon and thoron in soil and other porous materials was designed. The analysis of numerical investigation of radon and thoron transport in upper layers of soil revealed that thoron flux density from the earth surface does not depend on soil gas advective velocity and varies only with diffusion coefficient changes. This result showed the advantages of thoron using versus radon using in the suggested method. The comparison of the new method with existing ones previously developed. The method could be helpful for solving of problems of radon mass-transport in porous media and gaseous exchange between soil and atmosphere.

  15. Measurements of the electron particle diffusion coefficient with the JET multichannel reflectometer

    International Nuclear Information System (INIS)

    Sips, A.C.C.; Haas, J.C.M. de; Costley, A.E.; Prentice, R.

    1989-01-01

    Experimental determinations of the cross-field particle diffusion coefficient (D p ) are important in studies of transport in tokamak plasmas. D p has been determined from measurements of density perturbations following a sawtooth collapse, oscillating gas puff, and injected high velocity pellets. In each case the density changes have been measured using multichord interferometry and D p is obtained with an accuracy of typically 20%. In this paper, we present our most recent measurements of D p . The experimental data are compared with the prediction of a comprehensive numerical transport model which includes both outward going and inward going density pulses. (author) 8 refs., 6 figs

  16. Apparent diffusion coefficient measurement in a moving phantom simulating linear respiratory motion.

    Science.gov (United States)

    Kwee, Thomas C; Takahara, Taro; Muro, Isao; Van Cauteren, Marc; Imai, Yutaka; Nievelstein, Rutger A J; Mali, Willem P T M; Luijten, Peter R

    2010-10-01

    The aim of this study was to examine the effect of simulated linear respiratory motion on apparent diffusion coefficient (ADC) measurements. Six rectangular test tubes (14 × 92 mm) filled with either water, tomato ketchup, or mayonnaise were positioned in a box containing agarose gel. This box was connected to a double-acting pneumatic cylinder, capable of inducing periodic linear motion in the long-axis direction of the magnetic bore (23-mm stroke). Diffusion-weighted magnetic resonance imaging was performed for both the static and moving phantoms, and ADC measurements were made in the six test tubes in both situations. In the three test tubes whose long axes were parallel to the direction of motion, ADCs agreed well between the moving and static phantom situations. However, in two test tubes that were filled with fluids that had a considerably lower diffusion coefficient than the surrounding agarose gel, and whose long axes were perpendicular to the direction of motion, the ADCs agreed poorly between the moving and static phantom situations. ADC measurements of large homogeneous structures are not affected by linear respiratory motion. However, ADC measurements of inhomogeneous or small structures are affected by linear respiratory motion due to partial volume effects.

  17. Apparent diffusion coefficient measurement in a moving phantom simulating linear respiratory motion

    International Nuclear Information System (INIS)

    Kwee, T.C.; Takahara, Taro; Nievelstein, R.A.J.; Mali, W.P.T.M.; Luijten, P.R.; Muro, Isao; Imai, Yutaka; Cauteren, M. Van

    2010-01-01

    The aim of this study was to examine the effect of simulated linear respiratory motion on apparent diffusion coefficient (ADC) measurements. Six rectangular test tubes (14 x 92 mm) filled with either water, tomato ketchup, or mayonnaise were positioned in a box containing agarose gel. This box was connected to a double-acting pneumatic cylinder, capable of inducing periodic linear motion in the long-axis direction of the magnetic bore (23-mm stroke). Diffusion-weighted magnetic resonance imaging was performed for both the static and moving phantoms, and ADC measurements were made in the six test tubes in both situations. In the three test tubes whose long axes were parallel to the direction of motion, ADCs agreed well between the moving and static phantom situations. However, in two test tubes that were filled with fluids that had a considerably lower diffusion coefficient than the surrounding agarose gel, and whose long axes were perpendicular to the direction of motion, the ADCs agreed poorly between the moving and static phantom situations. ADC measurements of large homogeneous structures are not affected by linear respiratory motion. However, ADC measurements of inhomogeneous or small structures are affected by linear respiratory motion due to partial volume effects. (author)

  18. Direct rotating ring-disk measurement of the sodium borohydride diffusion coefficient in sodium hydroxide solutions

    Energy Technology Data Exchange (ETDEWEB)

    Chatenet, M. [Laboratoire d' Electrochimie et de Physico-chimie des Materiaux et des Interfaces, LEPMI, UMR 5631 CNRS/Grenoble-INP/UJF, 1130 rue de la piscine, BP75, 38402 Saint Martin d' Heres Cedex (France)], E-mail: Marian.Chatenet@phelma.grenoble-inp.fr; Molina-Concha, M.B. [Laboratoire d' Electrochimie et de Physico-chimie des Materiaux et des Interfaces, LEPMI, UMR 5631 CNRS/Grenoble-INP/UJF, 1130 rue de la piscine, BP75, 38402 Saint Martin d' Heres Cedex (France); El-Kissi, N. [Laboratoire de Rheologie, UMR 5520 CNRS/Grenoble-INP/UJF, 1301 rue de la piscine, 38041 Grenoble Cedex 9 (France); Parrour, G.; Diard, J.-P. [Laboratoire d' Electrochimie et de Physico-chimie des Materiaux et des Interfaces, LEPMI, UMR 5631 CNRS/Grenoble-INP/UJF, 1130 rue de la piscine, BP75, 38402 Saint Martin d' Heres Cedex (France)

    2009-07-15

    This paper presents the experimental determination of the diffusion coefficient of borohydride anion and solution kinematic viscosity for a large panel of NaOH + NaBH{sub 4} electrolytic solutions relevant for use as anolyte in Direct Borohydride Fuel Cells (DBFC). The diffusion coefficients have been measured by the transit-time technique on gold rotating ring-disk electrodes, and verified using other classical techniques reported in the literature, namely the Levich method and Electrochemical Impedance Spectroscopy on a gold RDE, or chronoamperometry at a gold microdisk. The agreement between these methods is generally good. The diffusion coefficients measured from the RRDE technique are however ca. twice larger than those previously reported in the literature (e.g. ca. 3 x 10{sup -5} cm{sup 2} s{sup -1} in 1 M NaOH + 0.01 M NaBH{sub 4} at 25 deg. C in the present study vs. ca. 1.6 x 10{sup -5} cm{sup 2} s{sup -1} in 1 M NaOH + 0.02 M NaBH{sub 4} at 30 deg. C in the literature, as measured by chronoamperometry at a gold microsphere), which is thoroughly discussed. Our measurements using chronoamperometry at a gold microdisk showed that such technique can yield diffusion coefficient values below what expected. The origin of such finding is explained in the frame of the formation of both a film of boron-oxide(s) at the surface of the (static) gold microdisk and the generation of H{sub 2} bubbles at the electrode surface (as a result of the heterogeneous hydrolysis at Au), which alter the access to the electrode surface and thus prevents efficient measurements. Such film formation and H{sub 2} bubbles generation is not so much of an issue for rotating electrodes thanks to the convection of electrolyte which sweeps the electrode surface. In addition, should such film be present, the transit-time determination technique on a RRDE displays the advantage of not being very sensible to its presence: the parameter measured is the time taken by a perturbation generated the

  19. Direct rotating ring-disk measurement of the sodium borohydride diffusion coefficient in sodium hydroxide solutions

    International Nuclear Information System (INIS)

    Chatenet, M.; Molina-Concha, M.B.; El-Kissi, N.; Parrour, G.; Diard, J.-P.

    2009-01-01

    This paper presents the experimental determination of the diffusion coefficient of borohydride anion and solution kinematic viscosity for a large panel of NaOH + NaBH 4 electrolytic solutions relevant for use as anolyte in Direct Borohydride Fuel Cells (DBFC). The diffusion coefficients have been measured by the transit-time technique on gold rotating ring-disk electrodes, and verified using other classical techniques reported in the literature, namely the Levich method and Electrochemical Impedance Spectroscopy on a gold RDE, or chronoamperometry at a gold microdisk. The agreement between these methods is generally good. The diffusion coefficients measured from the RRDE technique are however ca. twice larger than those previously reported in the literature (e.g. ca. 3 x 10 -5 cm 2 s -1 in 1 M NaOH + 0.01 M NaBH 4 at 25 deg. C in the present study vs. ca. 1.6 x 10 -5 cm 2 s -1 in 1 M NaOH + 0.02 M NaBH 4 at 30 deg. C in the literature, as measured by chronoamperometry at a gold microsphere), which is thoroughly discussed. Our measurements using chronoamperometry at a gold microdisk showed that such technique can yield diffusion coefficient values below what expected. The origin of such finding is explained in the frame of the formation of both a film of boron-oxide(s) at the surface of the (static) gold microdisk and the generation of H 2 bubbles at the electrode surface (as a result of the heterogeneous hydrolysis at Au), which alter the access to the electrode surface and thus prevents efficient measurements. Such film formation and H 2 bubbles generation is not so much of an issue for rotating electrodes thanks to the convection of electrolyte which sweeps the electrode surface. In addition, should such film be present, the transit-time determination technique on a RRDE displays the advantage of not being very sensible to its presence: the parameter measured is the time taken by a perturbation generated the disk to reach the ring trough a distance several orders

  20. Apparent diffusion coefficient measurement in glioma: Influence of region-of-interest determination methods on apparent diffusion coefficient values, interobserver variability, time efficiency, and diagnostic ability.

    Science.gov (United States)

    Han, Xu; Suo, Shiteng; Sun, Yawen; Zu, Jinyan; Qu, Jianxun; Zhou, Yan; Chen, Zengai; Xu, Jianrong

    2017-03-01

    To compare four methods of region-of-interest (ROI) placement for apparent diffusion coefficient (ADC) measurements in distinguishing low-grade gliomas (LGGs) from high-grade gliomas (HGGs). Two independent readers measured ADC parameters using four ROI methods (single-slice [single-round, five-round and freehand] and whole-volume) on 43 patients (20 LGGs, 23 HGGs) who had undergone 3.0 Tesla diffusion-weighted imaging and time required for each method of ADC measurements was recorded. Intraclass correlation coefficients (ICCs) were used to assess interobserver variability of ADC measurements. Mean and minimum ADC values and time required were compared using paired Student's t-tests. All ADC parameters (mean/minimum ADC values of three single-slice methods, mean/minimum/standard deviation/skewness/kurtosis/the10 th and 25 th percentiles/median/maximum of whole-volume method) were correlated with tumor grade (low versus high) by unpaired Student's t-tests. Discriminative ability was determined by receiver operating characteristic curves. All ADC measurements except minimum, skewness, and kurtosis of whole-volume ROI differed significantly between LGGs and HGGs (all P determination methods. Whole-volume histogram analysis did not yield better results than single-slice methods and took longer. Mean ADC value derived from single-round ROI is the most optimal parameter for differentiating LGGs from HGGs. 3 J. Magn. Reson. Imaging 2017;45:722-730. © 2016 International Society for Magnetic Resonance in Medicine.

  1. Methodology for using prompt gamma activation analysis to measure the binary diffusion coefficient of a gas in a porous medium

    International Nuclear Information System (INIS)

    Rios Perez, Carlos A.; Biegalski, Steve R.; Deinert, Mark R.

    2012-01-01

    Highlights: ► Prompt gamma activation analysis is used to study gas diffusion in a porous system. ► Diffusion coefficients are determined using prompt gamma activation analysis. ► Predictions concentrations fit experimental measurements with an R 2 of 0.98. - Abstract: Diffusion plays a critical role in determining the rate at which gases migrate through porous systems. Accurate estimates of diffusion coefficients are essential if gas transport is to be accurately modeled and better techniques are needed that can be used to measure these coefficients non-invasively. Here we present a novel method for using prompt gamma activation analysis to determine the binary diffusion coefficients of a gas in a porous system. Argon diffusion experiments were conducted in a 1 m long, 10 cm diameter, horizontal column packed with a SiO 2 sand. The temporal variation of argon concentration within the system was measured using prompt gamma activation analysis. The binary diffusion coefficient was obtained by comparing the experimental data with the predictions from a numerical model in which the diffusion coefficient was varied until the sum of square errors between experiment and model data was minimized. Predictions of argon concentration using the optimal diffusivity fit experimental measurements with an R 2 of 0.983.

  2. Measurement of Retinalamin diffusion coefficient in human sclera by optical spectroscopy

    Science.gov (United States)

    Genina, Elina A.; Bashkatov, Alexey N.; Zubkova, Elena A.; Kamenskikh, Tatiana G.; Tuchin, Valery V.

    2008-12-01

    The use of cytomedines (such as Retinalamin) in clinical practice has shown high effectiveness of the medicaments in ophthalmology. The study of diffusion of Retinalamin in scleral tissue is important for estimation of a drug dose delivered into inner tissue of eye, time of drug action, etc. In vitro measurements of spectral reflectance of sclera interacting with aqueous solution of Retinalamin have been carried out. Ten human sclera samples were included in the study. The results of the experiments have shown that penetration of Retinalamin into scleral tissue leads to the decrease of scleral reflectance due to optical immersion. Estimation of diffusion coefficient of studied solution has been made on the basis of analysis of optical reflectance dynamics of the sclera samples. The diffusion coefficient of Retinalamin in human scleral tissue was evaluated as (1.82±0.14)×10 -6 cm 2/s. The results are important for treatment of partial optic atrophy observed at primary open-angle glaucoma and others eye diseases.

  3. Extracting surface diffusion coefficients from batch adsorption measurement data: application of the classic Langmuir kinetics model.

    Science.gov (United States)

    Chu, Khim Hoong

    2017-11-09

    Surface diffusion coefficients may be estimated by fitting solutions of a diffusion model to batch kinetic data. For non-linear systems, a numerical solution of the diffusion model's governing equations is generally required. We report here the application of the classic Langmuir kinetics model to extract surface diffusion coefficients from batch kinetic data. The use of the Langmuir kinetics model in lieu of the conventional surface diffusion model allows derivation of an analytical expression. The parameter estimation procedure requires determining the Langmuir rate coefficient from which the pertinent surface diffusion coefficient is calculated. Surface diffusion coefficients within the 10 -9 to 10 -6  cm 2 /s range obtained by fitting the Langmuir kinetics model to experimental kinetic data taken from the literature are found to be consistent with the corresponding values obtained from the traditional surface diffusion model. The virtue of this simplified parameter estimation method is that it reduces the computational complexity as the analytical expression involves only an algebraic equation in closed form which is easily evaluated by spreadsheet computation.

  4. Study on the measurement method of diffusion coefficient for radon in the soil. 2

    International Nuclear Information System (INIS)

    Iida, Takao

    2000-03-01

    To investigate radon behavior in the soil at Ningyo Pass, the radon concentrations in the soil and the radon exhalation rate from soil surface were measured by four continuous soil radon monitoring systems, soil gas sampling method, and accumulation method. The radon concentrations in the soil measured with continuous soil radon monitoring systems varied form 5000 Bq·m -3 to 15000 Bq·m -3 at 10 cm to 40 cm depth. On the other hand, the radon concentrations measured by soil gas sampling method was 15000 Bq·m -3 at 15 cm depth. The accumulation method gives the vales of 0. 36∼0.68 Bq·m -2 ·s -1 for radon exhalation rate from soil surface. To simulate the radon transport in soil, the following parameters of the soil are important: radon diffusion coefficients, dry density, wet density, soil particle density, true density, water content and radium concentration. The measured radon diffusion coefficients in the soil were (1.61±0.09)x10 -6 m 2 s -1 , (8.68±0.23)x10 -7 m 2 s -1 ∼ (1.53±0.12)x10 -6 m 2 s -1 and (2.99±0.32)x10 -6 m 2 s -1 ∼ (4.39±0.43)x10 -6 m 2 s -1 for sandy soils of the campus of Nagoya University, Tsuruga peninsula, and Ningyo Pass, respectively. By using these parameters, the radon transport phenomena in the soil of two layers were calculated by analytical and numerical methods. The radon profile calculated by numerical method agrees fairly well with measured values. By covering of 2 m soil, the radon exhalation rate decreases to 1/4 by analytical method, and 3/5 by numerical method. The covering of normal soil is not so effective for reducing the radon exhalation rate. (author)

  5. Apparent Diffusion Coefficient Measurement in Mediastinal Lymphadenopathies: Differentiation between Benign and Malignant Lesions

    Directory of Open Access Journals (Sweden)

    Fethi Emre Ustabasioglu

    2017-01-01

    Full Text Available Objectives: We aimed to prospectively assess the diagnostic value of apparent diffusion coefficient (ADC measurement in the differentiation of benign and malignant mediastinal lymphadenopathies. Materials and Methods: The study included 63 consecutive patients (28 women, 35 men; mean age 59.3 years with 125 mediastinal lymphadenopathies. Echoplanar diffusion-weighted magnetic resonance imaging of the mediastinum was performed with b-factors of 0 and 600 mm2/s before mediastinoscopy and mediastinotomy, and ADC values were measured. The ADC values were compared with the histological results, and statistical analysis was done. P < 0.05 was considered statistically significant. Results: The mean ADC value of malignant mediastinal lymphadenopathy (1.030 ± 0.245 × 10−3 mm2/s was significantly lower (P < 0.05 when compared to benign lymphadenopathies (1.571 ± 0.559 × 10−3 mm2/s. For differentiating malignant from benign mediastinal lymphadenopathy, the best result was obtained when an ADC value of 1.334 × 10−3 mm2/s was used as a threshold value; area under the curve 0.848, accuracy 78.4%, sensitivity 66%, specificity of 86%, positive predictive value 76.7%, and negative predictive value of 79.2%. Interobserver agreement was excellent for ADC measurements. Conclusions: ADC measurements could be considered an important supportive method in differentiating benign from malignant mediastinal lymphadenopathies.

  6. Glucocorticoid treatment of brain tumor patients: changes of apparent diffusion coefficient values measured by MR diffusion imaging

    International Nuclear Information System (INIS)

    Minamikawa, Sosuke; Kono, Kinuko; Nakayama, Keiko; Yokote, Hiroyuki; Tashiro, Takahiko; Inoue, Yuichi; Nishio, Akimasa; Hara, Mitsuhiro

    2004-01-01

    Glucocorticoids (GCC) generally are administered to patients with brain tumors to relieve neurological symptoms by decreasing the water content in a peritumoral zone of edema. We hypothesized that diffusion imaging and apparent diffusion coefficient (ADC) values could detect subtle changes of water content in brain tumors and in peritumoral edema after GCC therapy. The study consisted of 13 patients with intra-axial brain tumor, and ADC was measured in the tumor, within peritumoral edema, and in normal white matter remote from the tumor before and after GCC therapy. ADC also was measured in normal white matter in four control patients with no intracranial disease who were treated with GCC for other indications. Conventional MR images showed no visually evident interval change in tumor size or the extent of peritumoral edema in any subject after GCC therapy, which nonetheless resulted in a decrease in mean ADC of 7.0% in tumors (P 0.05, not significant) and 5.8% in normal white matter (P<0.05). In patients with no intracranial disease, GCC therapy decreased mean ADC in white matter by 5.4% (P<0.05). ADC measurement can demonstrate subtle changes in the brain after GCC therapy that cannot be observed by conventional MR imaging. Measurement of ADC proved to be a sensitive means of assessing the effect of GCC therapy, even in the absence of visually discernible changes in conventional MR images. (orig.)

  7. Assessment and quantification of sources of variability in breast apparent diffusion coefficient (ADC) measurements at diffusion weighted imaging

    International Nuclear Information System (INIS)

    Giannotti, E.; Waugh, S.; Priba, L.; Davis, Z.; Crowe, E.; Vinnicombe, S.

    2015-01-01

    Highlights: • Inter-scan errors have minimal contribution to ADC measurement variability. • Intra-observer measures of ADC values in breast cancer are excellent. • ADC measures in whole tumour are more reproducible than minimum ADC measures. • ADC measurement error is most influenced by multiple readers. - Abstract: Purpose: Apparent Diffusion Coefficient (ADC) measurements are increasingly used for assessing breast cancer response to neoadjuvant chemotherapy although little data exists on ADC measurement reproducibility. The purpose of this work was to investigate and characterise the magnitude of errors in ADC measures that may be encountered in such follow-up studies- namely scanner stability, scan–scan reproducibility, inter- and intra- observer measures and the most reproducible measurement of ADC. Methods: Institutional Review Board approval was obtained for the prospective study of healthy volunteers and written consent acquired for the retrospective study of patient images. All scanning was performed on a 3.0-T MRI scanner. Scanner stability was assessed using an ice-water phantom weekly for 12 weeks. Inter-scan repeatability was assessed across two scans of 10 healthy volunteers (26–61 years; mean: 44.7 years). Inter- and intra-reader analysis repeatability was measured in 52 carcinomas from clinical patients (29–70 years; mean: 50.0 years) by measuring the whole tumor ADC value on a single slice with maximum tumor diameter (ADC S ) and the ADC value of a small region of interest (ROI) on the same slice (ADC min ). Repeatability was assessed using intraclass correlation coefficients (ICC) and coefficients of repeatability (CoR). Results: Scanner stability contributed 6% error to phantom ADC measurements (0.071 × 10 −3 mm 2 /s; mean ADC = 1.089 × 10 −3 mm 2 /s). The measured scan-scan CoR in the volunteers was 0.122 × 10 −3 mm 2 /s, contributing an error of 8% to the mean measured values (ADC scan1 = 1.529 × 10 −3 mm 2 /s; ADC scan

  8. Assessment and quantification of sources of variability in breast apparent diffusion coefficient (ADC) measurements at diffusion weighted imaging

    Energy Technology Data Exchange (ETDEWEB)

    Giannotti, E., E-mail: ytteb84@hotmail.com [Breast Imaging Department, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Waugh, S., E-mail: shelley.waugh@nhs.net [Department of Medical Physics, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Department of Clinical Radiology, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Priba, L., E-mail: lpriba@nhs.net [Department of Medical Physics, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Davis, Z., E-mail: zoedavis@doctors.org.uk [Breast Imaging Department, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Crowe, E., E-mail: e.crowe@nhs.net [Department of Clinical Radiology, Ninewells Hospital and Medical School, Dundee DD1 9SY (United Kingdom); Vinnicombe, S., E-mail: s.vinnicombe@dundee.ac.uk [Division of Imaging and Technology, Ninewells Hospital and Medical School, University of Dundee, Dundee DD1 9SY (United Kingdom)

    2015-09-15

    Highlights: • Inter-scan errors have minimal contribution to ADC measurement variability. • Intra-observer measures of ADC values in breast cancer are excellent. • ADC measures in whole tumour are more reproducible than minimum ADC measures. • ADC measurement error is most influenced by multiple readers. - Abstract: Purpose: Apparent Diffusion Coefficient (ADC) measurements are increasingly used for assessing breast cancer response to neoadjuvant chemotherapy although little data exists on ADC measurement reproducibility. The purpose of this work was to investigate and characterise the magnitude of errors in ADC measures that may be encountered in such follow-up studies- namely scanner stability, scan–scan reproducibility, inter- and intra- observer measures and the most reproducible measurement of ADC. Methods: Institutional Review Board approval was obtained for the prospective study of healthy volunteers and written consent acquired for the retrospective study of patient images. All scanning was performed on a 3.0-T MRI scanner. Scanner stability was assessed using an ice-water phantom weekly for 12 weeks. Inter-scan repeatability was assessed across two scans of 10 healthy volunteers (26–61 years; mean: 44.7 years). Inter- and intra-reader analysis repeatability was measured in 52 carcinomas from clinical patients (29–70 years; mean: 50.0 years) by measuring the whole tumor ADC value on a single slice with maximum tumor diameter (ADC{sub S}) and the ADC value of a small region of interest (ROI) on the same slice (ADC{sub min}). Repeatability was assessed using intraclass correlation coefficients (ICC) and coefficients of repeatability (CoR). Results: Scanner stability contributed 6% error to phantom ADC measurements (0.071 × 10{sup −3} mm{sup 2}/s; mean ADC = 1.089 × 10{sup −3} mm{sup 2}/s). The measured scan-scan CoR in the volunteers was 0.122 × 10{sup −3} mm{sup 2}/s, contributing an error of 8% to the mean measured values (ADC

  9. Novel Technique for Direct Measurement of the Plasma Diffusion Coefficient in Magnetized Plasma

    Czech Academy of Sciences Publication Activity Database

    Brotánková, Jana; Martines, E.; Adámek, Jiří; Stöckel, Jan; Popa, G.; Costin, C.; Ionita, G.; Schrittwieser, R.; Van Oost, G.

    2008-01-01

    Roč. 48, 5-7 (2008), s. 418-423 ISSN 0863-1042. [International Workshop on Electrical Probes in Magnetized Plasmas/7th./. Praha, 22.07.2007-25.07.2007] Institutional research plan: CEZ:AV0Z20430508 Keywords : Tokamak * probe diagnostics * diffusion coefficient Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.250, year: 2008

  10. Measurement of the Diffusion Coefficient of Water in RP-3 and RP-5 Jet Fuels Using Digital Holography Interferometry

    Science.gov (United States)

    Li, Chaoyue; Feng, Shiyu; Shao, Lei; Pan, Jun; Liu, Weihua

    2018-04-01

    The diffusion coefficient of water in jet fuel was measured employing double-exposure digital holographic interferometry to clarify the diffusion process and make the aircraft fuel system safe. The experimental method and apparatus are introduced in detail, and the digital image processing program is coded in MATLAB according to the theory of the Fourier transform. At temperatures ranging from 278.15 K to 333.15 K in intervals of 5 K, the diffusion coefficient of water in RP-3 and RP-5 jet fuels ranges from 2.6967 × 10 -10 m2·s-1 to 8.7332 × 10 -10 m2·s-1 and from 2.3517 × 10 -10 m2·s-1 to 8.0099 × 10-10 m2·s-1, respectively. The relationship between the measured diffusion coefficient and temperature can be well fitted by the Arrhenius law. The diffusion coefficient of water in RP-3 jet fuel is higher than that of water in RP-5 jet fuel at the same temperature. Furthermore, the viscosities of the two jet fuels were measured and found to be expressible in the form of the Arrhenius equation. The relationship among the diffusion coefficient, viscosity and temperature is analyzed according to the classic prediction model, namely the Stokes-Einstein correlation, and this correlation is further revised via experimental data to obtain a more accurate predication result.

  11. Apparent diffusion coefficient measurements in the differentiation between benign and malignant lesions: a systematic review.

    Science.gov (United States)

    Vermoolen, M A; Kwee, T C; Nievelstein, R A J

    2012-08-01

    To systematically review the value of apparent diffusion coefficient (ADC) measurement in the differentiation between benign and malignant lesions. A systematic search of the Medline/Pubmed and Embase databases revealed 109 relevant studies. Quality of these articles was assessed using the Quality Assessment of the Studies of Diagnostic Accuracy Included in Systematic Reviews (QUADAS) criteria. Reported ADC values of benign and malignant lesions were compared per organ. The mean quality score of the reviewed articles was 50%. Comparison of ADC values showed marked variation among studies and between benign and malignant lesions in various organs. In several organs, such as breast, liver, and uterus, ADC values discriminated well between benign and malignant lesions. In other organs, such as the salivary glands, thyroid, and pancreas, ADCs were not significantly different between benign and malignant lesions. The potential utility of ADC measurement for the characterisation of tumours differs per organ. Future well-designed studies are required before ADC measurements can be recommended for the differentiation of benign and malignant lesions. These future studies should use standardised acquisition protocols and provide complete reporting of study methods, to facilitate comparison of results and clinical implementation of ADC measurement for tumour characterisation.

  12. SPME-Based Ca-History Method for Measuring SVOC Diffusion Coefficients in Clothing Material.

    Science.gov (United States)

    Cao, Jianping; Liu, Ningrui; Zhang, Yinping

    2017-08-15

    Clothes play an important role in dermal exposure to indoor semivolatile organic compounds (SVOCs). The diffusion coefficient of SVOCs in clothing material (D m ) is essential for estimating SVOC sorption by clothing material and subsequent dermal exposure to SVOCs. However, few studies have reported the measured D m for clothing materials. In this paper, we present the solid-phase microextraction (SPME) based C a -history method. To the best of our knowledge, this is the first try to measure D m with known relative standard deviation (RSD). A thin sealed chamber is formed by a circular ring and two pieces of flat SVOC source materials that are tightly covered by the targeted clothing materials. D m is obtained by applying an SVOC mass transfer model in the chamber to the history of gas-phase SVOC concentrations (C a ) in the chamber measured by SPME. D m 's of three SVOCs, di-iso-butyl phthalate (DiBP), di-n-butyl phthalate (DnBP), and tris(1-chloro-2-propyl) phosphate (TCPP), in a cotton T-shirt can be obtained within 16 days, with RSD less than 3%. This study should prove useful for measuring SVOC D m in various sink materials. Further studies are expected to facilitate application of this method and investigate the effects of temperature, relative humidity, and clothing material on D m .

  13. Easy measurement of diffusion coefficients of EGFP-tagged plasma membrane proteins using k-space Image Correlation Spectroscopy

    DEFF Research Database (Denmark)

    Christensen, Eva Arnspang; Koffman, Jennifer Skaarup; Marlar, Saw

    2014-01-01

    Lateral diffusion and compartmentalization of plasma membrane proteins are tightly regulated in cells and thus, studying these processes will reveal new insights to plasma membrane protein function and regulation. Recently, k-Space Image Correlation Spectroscopy (kICS)1 was developed to enable...... routine measurements of diffusion coefficients directly from images of fluorescently tagged plasma membrane proteins, that avoided systematic biases introduced by probe photophysics. Although the theoretical basis for the analysis is complex, the method can be implemented by nonexperts using a freely...... to the correlation function yields the diffusion coefficient. This paper provides a step-by-step guide to the image analysis and measurement of diffusion coefficients via kICS. First, a high frame rate image sequence of a fluorescently labeled plasma membrane protein is acquired using a fluorescence microscope Then...

  14. Mass diffusion coefficient measurement for vitreous humor using FEM and MRI

    Science.gov (United States)

    Rattanakijsuntorn, Komsan; Penkova, Anita; Sadha, Satwindar S.

    2018-01-01

    In early studies, the ‘contour method’ for determining the diffusion coefficient of the vitreous humor was developed. This technique relied on careful injection of an MRI contrast agent (surrogate drug) into the vitreous humor of fresh bovine eyes, and tracking the contours of the contrast agent in time. In addition, an analytical solution was developed for the theoretical contours built on point source model for the injected surrogate drug. The match between theoretical and experimental contours as a least square fit, while floating the diffusion coefficient, led to the value of the diffusion coefficient. This method had its limitation that the initial injection of the surrogate had to be spherical or ellipsoidal because of the analytical result based on the point-source model. With a new finite element model for the analysis in this study, the technique is much less restrictive and handles irregular shapes of the initial bolus. The fresh bovine eyes were used for drug diffusion study in the vitreous and three contrast agents of different molecular masses: gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA, 938 Da), non-ionic gadoteridol (Prohance, 559 Da), and bovine albumin conjugated with gadolinium (Galbumin, 74 kDa) were used as drug surrogates to visualize the diffusion process by MRI. The 3D finite element model was developed to determine the diffusion coefficients of these surrogates with the images from MRI. This method can be used for other types of bioporous media provided the concentration profile can be visualized (by methods such as MRI or fluorescence).

  15. Measurement of methanol diffusion coefficient in polymer electrode membrane by small NMR sensor. 1st report. Development of method of measure methanol diffusion coefficient and evaluation of measured results

    International Nuclear Information System (INIS)

    Ogawa, Kuniyasu; Haishi, Tomoyuki; Ito, Kohei

    2010-01-01

    A method for measuring the diffusion coefficient of methanol in a polymer electrolyte membrane (PEM) was developed using the NMR method. A circular coil of 0.6mm inside diameter was used as a small NMR sensor. The PEM was inserted in a penetration cell, where methanol solvent is supplied to one side of the PEM and nitrogen gas is supplied to the other side of the PEM. The small NMR sensor was placed on the nitrogen gas side of the PEM. The small NMR sensor detects the NMR signal from the methanol solvent which permeates the PEM. The CH and OH components of the methanol solvent were obtained from the NMR signal by spectral analysis. The methanol concentration in the PEM was determined by the ratio of CH to OH components. The methanol concentration was acquired at intervals of 30s and was measured for 2000s. After 1500 seconds, the methanol concentration in the PEM reaches a steady state. The final methanol concentration was about 20% of the methanol concentration of the solvent. It assumed that the diffusion phenomenon of methanol in a PEM was a one-dimensional transport phenomenon, and the time-dependent change of methanol concentration was analyzed by parameterizing the diffusion coefficient. The diffusion coefficient of methanol in a PEM was determined by comparison with the measurement result of the time change of methanol concentration and the analysis results. The concentration difference diffusion coefficient of methanol in PEM obtained using this method was 3.5 * 10 -10 m 2 /s. (author)

  16. Simulation study on the measurements of diffusion coefficients in solid materials by short-lived radiotracer beams

    CERN Document Server

    Jeong, S C; Kawakami, H

    2003-01-01

    We have examined, by a computer simulation, an on-line measurement of diffusion coefficients by using a short-lived alpha particle emitter, sup 8 Li (half life of 0.84s), as a radiotracer. The energy spectra of alpha particles emitted from diffusing sup 8 Li primarily implanted in the sample of LiAl ar simulated as a measure of the diffusion of sup 8 Li in the sample. As a possible time sequence for the measurement, a time cycle of 6s, i.e. the implantation of sup 8 Li for 1.5s and subsequent diffusion for 4.5s, is supposed. The sample is primarily set on a given temperature for the measurement. The time-dependent yields of alpha particles during the time cycle reveal the possibility to measure the diffusion coefficient with an accuracy of 10% if larger than 1 x 10 sup - sup 9 cm sup 2 /s, by the comparison with the experimental spectra measured at the temperature, i.e. at a certain diffusion coefficient. (author)

  17. Application of wet effluent diffusion denuder for measurement of uptake coefficient of gaseous pollutants

    Czech Academy of Sciences Publication Activity Database

    Motyka, K.; Mikuška, Pavel; Večeřa, Zbyněk

    2011-01-01

    Roč. 84, č. 2 (2011), s. 519-523 ISSN 0039-9140 R&D Projects: GA MŽP SP/1A3/148/08; GA MŽP SP/1A3/55/08; GA MŽP SP/1B7/189/07 Institutional research plan: CEZ:AV0Z40310501 Keywords : collection efficiency * wet effluent diffusion denuder * uptake coefficient Subject RIV: CB - Analytical Chemistry, Separation Impact factor: 3.794, year: 2011

  18. Self-normalizing multiple-echo technique for measuring the in vivo apparent diffusion coefficient

    International Nuclear Information System (INIS)

    Perman, W.H.; Gado, M.; Sandstrom, J.C.

    1989-01-01

    This paper presents work to develop a new technique for quantitating the in vivo apparent diffusion/perfusion coefficient (ADC) by obtaining multiple data points from only two images with the capability to normalize the data from consecutive images, thus minimizing the effect of interimage variation. Two multiple-echo (six-to eight-echo) cardiac-gated images are obtained, one without and one with additional diffusion/perfusion encoding gradients placed about the 180 RF pulses of all but the first echo. Since the first echoes of both images have identical pulse sequence parameters, variations in signal intensity-between the first echoes represent image-to-image variation. The signal intensities of the subsequent echoes with additional diffusion/perfusion encoding gradients are then normalized by using the ratio of the first-echo signal intensities

  19. Mis-estimation and bias of hyperpolarized apparent diffusion coefficient measurements due to slice profile effects.

    Science.gov (United States)

    Gordon, Jeremy W; Milshteyn, Eugene; Marco-Rius, Irene; Ohliger, Michael; Vigneron, Daniel B; Larson, Peder E Z

    2017-09-01

    The purpose of this work was to explore the impact of slice profile effects on apparent diffusion coefficient (ADC) mapping of hyperpolarized (HP) substrates. Slice profile effects were simulated using a Gaussian radiofrequency (RF) pulse with a variety of flip angle schedules and b-value ordering schemes. A long T 1 water phantom was used to validate the simulation results, and ADC mapping of HP [ 13 C, 15 N 2 ]urea was performed on the murine liver to assess these effects in vivo. Slice profile effects result in excess signal after repeated RF pulses, causing bias in HP measurements. The largest error occurs for metabolites with small ADCs, resulting in up to 10-fold overestimation for metabolites that are in more-restricted environments. A mixed b-value scheme substantially reduces this bias, whereas scaling the slice-select gradient can mitigate it completely. In vivo, the liver ADC of hyperpolarized [ 13 C, 15 N 2 ]urea is nearly 70% lower (0.99 ± 0.22 vs 1.69 ± 0.21 × 10 -3 mm 2 /s) when slice-select gradient scaling is used. Slice profile effects can lead to bias in HP ADC measurements. A mixed b-value ordering scheme can reduce this bias compared to sequential b-value ordering. Slice-select gradient scaling can also correct for this deviation, minimizing bias and providing more-precise ADC measurements of HP substrates. Magn Reson Med 78:1087-1092, 2017. © 2016 International Society for Magnetic Resonance in Medicine. © 2016 International Society for Magnetic Resonance in Medicine.

  20. Diffusion coefficient for anomalous transport

    International Nuclear Information System (INIS)

    1986-01-01

    A report on the progress towards the goal of estimating the diffusion coefficient for anomalous transport is given. The gyrokinetic theory is used to identify different time and length scale inherent to the characteristics of plasmas which exhibit anomalous transport

  1. A gravitational procedure to measure the diffusion coefficient of mater in porous materials : a case study on concrete

    NARCIS (Netherlands)

    Zanden, van der A.J.J.; Taher, A.

    2014-01-01

    A new procedure is presented with which the diffusion coefficient of water in partially saturated porous materials can be measured. The first step in the procedure is the creation of a non-equilibrium situation inside a sample by placing it into a centrifuge. In the second step, the mass of the

  2. Diffusion coefficients of paracetamol in aqueous solutions

    International Nuclear Information System (INIS)

    Ribeiro, Ana C.F.; Barros, Marisa C.F.; Veríssimo, Luís M.P.; Santos, Cecilia I.A.V.; Cabral, Ana M.T.D.P.V.; Gaspar, Gualter D.; Esteso, Miguel A.

    2012-01-01

    Highlights: ► Mutual diffusion coefficients of paracetamol in aqueous dilute solutions. ► Influence of the thermodynamic factors on the variation of their mutual diffusion coefficients. ► Estimation of the mutual limiting diffusion coefficients of the molecular, D m 0 , and ionized forms, D ± 0 , of this drug. - Abstract: Binary mutual diffusion coefficients measured by the Taylor dispersion method, for aqueous solutions of paracetamol (PA) at concentrations from (0.001 to 0.050) mol·dm −3 at T = 298.15 K, are reported. From the Nernst–Hartley equation and our experimental results, the limiting diffusion coefficient of this drug and its thermodynamic factors are estimated, thereby contributing in this way to a better understanding of the structure of such systems and of their thermodynamic behaviour in aqueous solution at different concentrations.

  3. Measurement of Diffusion Coefficients of Parabens and Steroids in Water and 1-Octanol

    OpenAIRE

    関, 俊暢; 持田, 純子; 岡本, 麻衣子; 細谷, 治; 從二, 和彦; Morimoto, Kazuhiro

    2003-01-01

    Diffusion coefficients (D) of parabens and steroids in water and 1-octanol were determined by using the chromatographic broadening method at 37 °C, and the relationships between the D values and the physicochemical properties of the drugs were discussed. The D values in 1-octanol were lower than those in water because of the higher viscosity of 1-octanol. The D values depend on not only the molecular weight (MW), but also the lipophilicity of the drugs in water and on the ability for hydrogen...

  4. Determination of malignancy and characterization of hepatic tumor type with diffusion-weighted magnetic resonance imaging: comparison of apparent diffusion coefficient and intravoxel incoherent motion-derived measurements.

    Science.gov (United States)

    Doblas, Sabrina; Wagner, Mathilde; Leitao, Helena S; Daire, Jean-Luc; Sinkus, Ralph; Vilgrain, Valérie; Van Beers, Bernard E

    2013-10-01

    The objective of this study was to compare the value of the apparent diffusion coefficient (ADC) determined with 3 b values and the intravoxel incoherent motion (IVIM)-derived parameters in the determination of malignancy and characterization of hepatic tumor type. Seventy-six patients with 86 solid hepatic lesions, including 8 hemangiomas, 20 lesions of focal nodular hyperplasia, 9 adenomas, 30 hepatocellular carcinomas, 13 metastases, and 6 cholangiocarcinomas, were assessed in this prospective study. Diffusion-weighted images were acquired with 11 b values to measure the ADCs (with b = 0, 150, and 500 s/mm) and the IVIM-derived parameters, namely, the pure diffusion coefficient and the perfusion-related diffusion fraction and coefficient. The diffusion parameters were compared between benign and malignant tumors and between tumor types, and their diagnostic value in identifying tumor malignancy was assessed. The apparent and pure diffusion coefficients were significantly higher in benign than in malignant tumors (benign: 2.32 [0.87] × 10 mm/s and 1.42 [0.37] × 10 mm/s vs malignant: 1.64 [0.51] × 10 mm/s and 1.14 [0.28] × 10 mm/s, respectively; P coefficients provided similar accuracy in assessing tumor malignancy (areas under the receiver operating characteristic curve of 0.770 and 0.723, respectively). In the multigroup analysis, the ADC was found to be significantly higher in hemangiomas than in hepatocellular carcinomas, metastases, and cholangiocarcinomas. In the same manner, it was higher in lesions of focal nodular hyperplasia than in metastases and cholangiocarcinomas. However, the pure diffusion coefficient was significantly higher only in hemangiomas versus hepatocellular and cholangiocellular carcinomas. Compared with the ADC, the diffusion parameters derived from the IVIM model did not improve the determination of malignancy and characterization of hepatic tumor type.

  5. ICP-MS measurement of silver diffusion coefficient in graphite IG-110 between 1048K and 1284K

    Science.gov (United States)

    Carter, L. M.; Seelig, J. D.; Brockman, J. D.; Robertson, J. D.; Loyalka, S. K.

    2018-01-01

    Silver-110m has been shown to permeate intact silicon carbide and pyrolytic carbon coating layers of the TRISO fuel particles during normal High Temperature Gas-Cooled Reactor (HTGR) operational conditions. The diffusion coefficients for silver in graphite IG-110 measured using a release method designed to simulate HTGR conditions of high temperature and flowing helium in the temperature range 1048-1253 K are reported. The measurements were made using spheres milled from IG-110 graphite that were infused with silver using a pressure vessel technique. The Ag diffusion was measured using a time release technique with an ICP-MS instrument for detection. The results of this work are:

  6. A new technique to measure fission-product diffusion coefficients in UO2 fuel

    International Nuclear Information System (INIS)

    Hocking, W.H.; Verrall, R.A.; Bushby, S.J.

    1999-01-01

    This paper describes a new out-reactor technique for the measurement of fission-product diffusion rates in UO 2 . The technique accurately simulates in-reactor fission-fragment effects: a thermal diffusion that is due to localized mixing in the fission track, radiation-enhanced diffusion that is due to point-defect creation by fission fragments, and bubble resolution. The technique utilizes heavy-ion accelerators - low energy (40 keV to 1 MeV) for fission-product implantation, high energy (72 MeV) to create fission-fragment damage effects, and secondary ion mass spectrometry (SIMS) for measuring the depth profile of the implanted species. Preliminary results are presented from annealing tests (not in the 72 MeV ion flux) at 1465 deg. C and 1650 deg. C at low and high concentrations of fission products. (author)

  7. Measurement of ageing effect on chloride diffusion coefficients in cementitious matrices

    International Nuclear Information System (INIS)

    Andrade, C.; Castellote, M.; D'Andrea, R.

    2011-01-01

    Most of the low-level nuclear waste disposal facilities are based in engineered multi barrier systems where reinforced concrete is one of the basic materials. The calculation of the time until steel reinforcement depassivation is a need due to the demand of prediction of the service life of concrete structures in radioactive repositories. In doing that, one of the main steps is the transport of chloride ions towards the reinforcement, as one of the most aggressive agents for the rebars in concrete is chloride ions. Ageing of concrete related to chloride penetration leads to significant decrease of the 'apparent diffusion' coefficient with time. If this effect is not considered, considerable bias can be introduced when predicting service life of reinforced concrete of repositories. Several effects have been addressed on their influence on the ageing of concrete, including the evolution with time of the concrete pore refinement, the binding of chlorides to the cement phases and to the changes of chloride 'surface concentration'. These effects have been studied in specimens made with different mixes trying to represent a wide range of mineral addition proportions. The analysis of their evolution with time has shown that the resistivity alone or the joint consideration of resistivity and binding capacity (C b /C f ), are appropriate parameters to appraise the diffusivity ageing. For practical reasons, an accelerated procedure is proposed in order to calculate ageing for short periods of time.

  8. Measurement of diffusion coefficients of parabens and steroids in water and 1-octanol.

    Science.gov (United States)

    Seki, Toshinobu; Mochida, Junko; Okamoto, Maiko; Hosoya, Osamu; Juni, Kazuhiko; Morimoto, Kazuhiro

    2003-06-01

    Diffusion coefficients (D) of parabens and steroids in water and 1-octanol were determined by using the chromatographic broadening method at 37 degrees C, and the relationships between the D values and the physicochemical properties of the drugs were discussed. The D values in 1-octanol were lower than those in water because of the higher viscosity of 1-octanol. The D values depend on not only the molecular weight (MW), but also the lipophilicity of the drugs in water and on the ability for hydrogen-bonding in 1-octanol. When the lipophilic index (LI), calculated from the retention time using in a reverse-phase column, was used as a parameter of drug lipophilicity, the following equation was obtained for D in water (D(w)); log D(w)=-0.215.log MW-0.077.log LI-4.367. When the hydrogen bond index (HI), the logarithm of the ratio of the partition coefficient of the drugs in 1-octanol and cyclohexane, was used as an index of hydrogen-bonding, the following equation was obtained for D in 1-octanol (D(o)); log D(o)=-0.690.log MW-0.074.log HI-4.085.

  9. Measurement of diffusion coefficient of thallium ion in H2O and D2O systems at different concentrations

    International Nuclear Information System (INIS)

    Das, A.; Changdar, S.N.

    1992-01-01

    Sliding cell method, developed in our laboratory, has been used to measure the inter diffusion coefficient of thallium ion in thallous sulphate solution over a wide concentration range using both water and heavy water as solvent at 35degC. The results have been analysed from the point of view of both ion-ion and ion-solvent interactions. The comparison of the diffusivities of the same ion in D 2 O and H 2 O electrolyte solutions at the same temperature indicate that the addition of salt affects the two solvent differently. (author). 8 refs., 1 fig., 1 tab

  10. Measurement setup for the simultaneous determination of diffusivity and Seebeck coefficient in a multi-anvil apparatus.

    Science.gov (United States)

    Jacobsen, M K; Liu, W; Li, B

    2012-09-01

    In this paper, a high pressure setup is presented for performing simultaneous measurements of Seebeck coefficient and thermal diffusivity in multianvil apparatus for the purpose of enhancing the study of transport phenomena. Procedures for the derivation of Seebeck coefficient and thermal diffusivity/conductivity, as well as their associated sources of errors, are presented in detail, using results obtained on the filled skutterudite, Ce(0.8)Fe(3)CoSb(12,) up to 12 GPa at ambient temperature. Together with recent resistivity and sound velocity measurements in the same apparatus, these developments not only provide the necessary data for a self-consistent and complete characterization of the figure of merit of thermoelectric materials under pressure, but also serve as an important tool for furthering our knowledge of the dynamics and interplay between these transport phenomena.

  11. Form of multicomponent Fickian diffusion coefficients matrix

    International Nuclear Information System (INIS)

    Wambui Mutoru, J.; Firoozabadi, Abbas

    2011-01-01

    Highlights: → Irreversible thermodynamics establishes form of multicomponent diffusion coefficients. → Phenomenological coefficients and thermodynamic factors affect sign of diffusion coefficients. → Negative diagonal elements of diffusion coefficients matrix can occur in non-ideal mixtures. → Eigenvalues of the matrix of Fickian diffusion coefficients may not be all real. - Abstract: The form of multicomponent Fickian diffusion coefficients matrix in thermodynamically stable mixtures is established based on the form of phenomenological coefficients and thermodynamic factors. While phenomenological coefficients form a symmetric positive definite matrix, the determinant of thermodynamic factors matrix is positive. As a result, the Fickian diffusion coefficients matrix has a positive determinant, but its elements - including diagonal elements - can be negative. Comprehensive survey of reported diffusion coefficients data for ternary and quaternary mixtures, confirms that invariably the determinant of the Fickian diffusion coefficients matrix is positive.

  12. Correlation and prediction of gaseous diffusion coefficients.

    Science.gov (United States)

    Marrero, T. R.; Mason, E. A.

    1973-01-01

    A new correlation method for binary gaseous diffusion coefficients from very low temperatures to 10,000 K is proposed based on an extended principle of corresponding states, and having greater range and accuracy than previous correlations. There are two correlation parameters that are related to other physical quantities and that are predictable in the absence of diffusion measurements. Quantum effects and composition dependence are included, but high-pressure effects are not. The results are directly applicable to multicomponent mixtures.

  13. Influence of diffuse reflectance measurement accuracy on the scattering coefficient in determination of optical properties with integrating sphere optics (a secondary publication).

    Science.gov (United States)

    Horibe, Takuro; Ishii, Katsunori; Fukutomi, Daichi; Awazu, Kunio

    2015-12-30

    An estimation error of the scattering coefficient of hemoglobin in the high absorption wavelength range has been observed in optical property calculations of blood-rich tissues. In this study, the relationship between the accuracy of diffuse reflectance measurement in the integrating sphere and calculated scattering coefficient was evaluated with a system to calculate optical properties combined with an integrating sphere setup and the inverse Monte Carlo simulation. Diffuse reflectance was measured with the integrating sphere using a small incident port diameter and optical properties were calculated. As a result, the estimation error of the scattering coefficient was improved by accurate measurement of diffuse reflectance. In the high absorption wavelength range, the accuracy of diffuse reflectance measurement has an effect on the calculated scattering coefficient.

  14. Influence of fluid-attenuated inversion-recovery on stroke apparent diffusion coefficient measurements and its clinical application

    Energy Technology Data Exchange (ETDEWEB)

    Ni Jianming [Medical Imaging Department, Wuxi Second Hospital Affiliated Nanjing Medical University, 68 Zhong Shan Road, Wuxi, Jiangsu Province 214002 (China); Radiology Department, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Urumqi Middle Road, Shanghai 200040 (China); Nuclear Medicine Department, Renji Hospital, Medical School of Jiaotong University, Dongfang Road 1630, Shanghai 200127 (China); Mogensen, Monique A. [Department of Radiology, Division of Neuroradiology, University of Southern California, Los Angeles, CA (United States); Chen Zengai [Radiology Department, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Urumqi Middle Road, Shanghai 200040 (China); Nuclear Medicine Department, Renji Hospital, Medical School of Jiaotong University, Dongfang Road 1630, Shanghai 200127 (China); Shuang Chen; Shen Tianzhen [Radiology Department, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Urumqi Middle Road, Shanghai 200040 (China); Huang Gang, E-mail: huang2802@163.co [Nuclear Medicine Department, Renji Hospital, Medical School of Jiaotong University, Dongfang Road 1630, Shanghai 200127 (China)

    2010-08-15

    Background and purpose: The application of a fluid-attenuated inversion-recovery pulse with a conventional diffusion-weighted MRI sequence (FLAIR DWI) decreases the partial volume effects from cerebrospinal fluid on apparent diffusion coefficient (ADC) measurements. For this reason, FLAIR DWI may be more useful in the evaluation of ischemic stroke, but few studies have looked at the effect of FLAIR on ADC measurements in this setting. This study quantitatively compares FLAIR DWI and conventional DWI in ischemic stroke of varying ages to assess the potential advantages of this technique. Methods: We respectively analyzed 139 DWI studies in patients with ischemic stroke with and without FLAIR at varying time points ranging from hyperacute to chronic. ADC values were measured in each lesion, as well as in the contralateral normal side. Comparisons were made between the ADC values obtained from the DWI sequences with and without FLAIR for both the lesion and the normal contralateral side. Results: The ADC measurements within the ischemic lesion were very similar on FLAIR DWI and conventional DWI for lesions less than 14 days old (p > 0.05), but were significantly decreased on FLAIR DWI for lesions between 15 and 30 days old and in lesions >31 days old (chronic stage) (p < 0.01). The contralateral ADC values were all significantly decreased on the FLAIR DWI sequence compared with conventional DWI (p < 0.01). Conclusions: The application of an inversion pulse does not significantly affect the ADC values for early stage ischemic stroke (less than 14 days from symptom onset), but results in a more accurate relative ADC measurement by reducing the cerebrospinal fluid partial volume effects of the normal contralateral side. In addition, combined with the conventional DWI, FLAIR DWI may be helpful in determining the age of ischemic lesions.

  15. Effective Diffusion Coefficients in Coal Chars

    DEFF Research Database (Denmark)

    Johnsson, Jan Erik; Jensen, Anker

    2001-01-01

    Knowledge of effective diffusion coefficients in char particles is important when interpreting experimental reactivity measurements and modeling char combustion or NO and N2O reduction. In this work, NO and N2O reaction with a bituminous coal char was studied in a fixed-bed quartz glass reactor....... In the case of strong pore diffusion limitations, the error in the interpretation of experimental results using the mean pore radius could be a factor of 5 on the intrinsic rate constant. For an average coal char reacting with oxygen at 1300 K, this would be the case for particle sizes larger than about 50...

  16. Diffusion weighted imaging of the normal breast: reproducibility of apparent diffusion coefficient measurements and variation with menstrual cycle and menopausal status

    International Nuclear Information System (INIS)

    O'Flynn, Elizabeth A.M.; Morgan, Veronica A.; Giles, Sharon L.; de Souza, Nandita M.

    2012-01-01

    To establish the reproducibility of apparent diffusion coefficient (ADC) measurements in normal fibroglandular breast tissue and to assess variation in ADC values with phase of the menstrual cycle and menopausal status. Thirty-one volunteers (13 premenopausal, 18 postmenopausal) underwent magnetic resonance twice (interval 11-22 days) using diffusion-weighted MRI. ADC total and a perfusion-insensitive ADC high (omitting b = 0) were calculated. Reproducibility and inter-observer variability of mean ADC values were assessed. The difference in mean ADC values between the two phases of the menstrual cycle and the postmenopausal breast were evaluated. ADC total and ADC high showed good reproducibility (r% = 17.6, 22.4). ADC high showed very good inter-observer agreement (kappa = 0.83). The intraclass correlation coefficients (ICC) were 0.93 and 0.91. Mean ADC values were significantly lower in the postmenopausal breast (ADC total 1.46 ± 0.3 x 10 -3 mm 2 /s, ADC high 1.33 ± 0.3 x 10 -3 mm 2 /s) compared with the premenopausal breast (ADC total 1.84 ± 0.26 x 10 -3 mm 2 /s, ADC high 1.77 ± 0.26 x 10 -3 mm 2 /s; both P total P = 0.2, ADC high P = 0.24) or between postmenopausal women taking or not taking oestrogen supplements (ADC total P = 0.6, ADC high P = 0.46). ADC values in fibroglandular breast tissue are reproducible. Lower ADC values within the postmenopausal breast may reduce diffusion-weighted contrast and have implications for accurately detecting tumours. (orig.)

  17. Diffusion weighted imaging of the normal breast: reproducibility of apparent diffusion coefficient measurements and variation with menstrual cycle and menopausal status

    Energy Technology Data Exchange (ETDEWEB)

    O' Flynn, Elizabeth A.M.; Morgan, Veronica A.; Giles, Sharon L. [Cancer Research UK and ESPSRC Cancer Imaging Centre, Clinical Magnetic Resonance Group, Surrey (United Kingdom); deSouza, Nandita M. [Royal Marsden NHS Foundation Trust, Clinical Magnetic Resonance Group, Institute of Cancer Research, Surrey (United Kingdom)

    2012-07-15

    To establish the reproducibility of apparent diffusion coefficient (ADC) measurements in normal fibroglandular breast tissue and to assess variation in ADC values with phase of the menstrual cycle and menopausal status. Thirty-one volunteers (13 premenopausal, 18 postmenopausal) underwent magnetic resonance twice (interval 11-22 days) using diffusion-weighted MRI. ADC{sub total} and a perfusion-insensitive ADC{sub high} (omitting b = 0) were calculated. Reproducibility and inter-observer variability of mean ADC values were assessed. The difference in mean ADC values between the two phases of the menstrual cycle and the postmenopausal breast were evaluated. ADC{sub total} and ADC{sub high} showed good reproducibility (r% = 17.6, 22.4). ADC{sub high} showed very good inter-observer agreement (kappa = 0.83). The intraclass correlation coefficients (ICC) were 0.93 and 0.91. Mean ADC values were significantly lower in the postmenopausal breast (ADC{sub total} 1.46 {+-} 0.3 x 10{sup -3} mm{sup 2}/s, ADC{sub high} 1.33 {+-} 0.3 x 10{sup -3} mm{sup 2}/s) compared with the premenopausal breast (ADC{sub total} 1.84 {+-} 0.26 x 10{sup -3} mm{sup 2}/s, ADC{sub high} 1.77 {+-} 0.26 x 10{sup -3} mm{sup 2}/s; both P < 0.001). No significant difference was seen in ADC values in relation to menstrual cycle (ADC{sub total} P = 0.2, ADC{sub high} P = 0.24) or between postmenopausal women taking or not taking oestrogen supplements (ADC{sub total} P = 0.6, ADC{sub high} P = 0.46). ADC values in fibroglandular breast tissue are reproducible. Lower ADC values within the postmenopausal breast may reduce diffusion-weighted contrast and have implications for accurately detecting tumours. (orig.)

  18. New definition of the cell diffusion coefficient

    International Nuclear Information System (INIS)

    Koehler, P.

    1975-01-01

    As was shown in a recent work by Gelbard, the usually applied Benoist definition of the cell diffusion coefficient gives two different values if two different definitions of the cell are made. A new definition is proposed that preserves the neutron balance for the homogenized lattice and that is independent of the cell definition. The resulting diffusion coefficient is identical with the main term of Benoist's diffusion coefficient

  19. Determination of diffusion coefficients of carbon dioxide in water between 268 and 473 K in a high-pressure capillary optical cell with in situ Raman spectroscopic measurements

    Science.gov (United States)

    Lu, Wanjun; Guo, Huirong; Chou, I.-Ming; Burruss, R.C.; Li, Lanlan

    2013-01-01

    Accurate values of diffusion coefficients for carbon dioxide in water and brine at reservoir conditions are essential to our understanding of transport behavior of carbon dioxide in subsurface pore space. However, the experimental data are limited to conditions at low temperatures and pressures. In this study, diffusive transfer of carbon dioxide in water at pressures up to 45 MPa and temperatures from 268 to 473 K was observed within an optical capillary cell via time-dependent Raman spectroscopy. Diffusion coefficients were estimated by the least-squares method for the measured variations in carbon dioxide concentration in the cell at various sample positions and time. At the constant pressure of 20 MPa, the measured diffusion coefficients of carbon dioxide in water increase with increasing temperature from 268 to 473 K. The relationship between diffusion coefficient of carbon dioxide in water [D(CO2) in m2/s] and temperature (T in K) was derived with Speedy–Angell power-law approach as: D(CO2)=D0[T/Ts-1]m where D0 = 13.942 × 10−9 m2/s, Ts = 227.0 K, and m = 1.7094. At constant temperature, diffusion coefficients of carbon dioxide in water decrease with pressure increase. However, this pressure effect is rather small (within a few percent).

  20. Measuring the apparent diffusion coefficient in primary rectal tumors: is there a benefit in performing histogram analyses?

    Science.gov (United States)

    van Heeswijk, Miriam M; Lambregts, Doenja M J; Maas, Monique; Lahaye, Max J; Ayas, Z; Slenter, Jos M G M; Beets, Geerard L; Bakers, Frans C H; Beets-Tan, Regina G H

    2017-06-01

    The apparent diffusion coefficient (ADC) is a potential prognostic imaging marker in rectal cancer. Typically, mean ADC values are used, derived from precise manual whole-volume tumor delineations by experts. The aim was first to explore whether non-precise circular delineation combined with histogram analysis can be a less cumbersome alternative to acquire similar ADC measurements and second to explore whether histogram analyses provide additional prognostic information. Thirty-seven patients who underwent a primary staging MRI including diffusion-weighted imaging (DWI; b0, 25, 50, 100, 500, 1000; 1.5 T) were included. Volumes-of-interest (VOIs) were drawn on b1000-DWI: (a) precise delineation, manually tracing tumor boundaries (2 expert readers), and (b) non-precise delineation, drawing circular VOIs with a wide margin around the tumor (2 non-experts). Mean ADC and histogram metrics (mean, min, max, median, SD, skewness, kurtosis, 5th-95th percentiles) were derived from the VOIs and delineation time was recorded. Measurements were compared between the two methods and correlated with prognostic outcome parameters. Median delineation time reduced from 47-165 s (precise) to 21-43 s (non-precise). The 45th percentile of the non-precise delineation showed the best correlation with the mean ADC from the precise delineation as the reference standard (ICC 0.71-0.75). None of the mean ADC or histogram parameters showed significant prognostic value; only the total tumor volume (VOI) was significantly larger in patients with positive clinical N stage and mesorectal fascia involvement. When performing non-precise tumor delineation, histogram analysis (in specific 45th ADC percentile) may be used as an alternative to obtain similar ADC values as with precise whole tumor delineation. Histogram analyses are not beneficial to obtain additional prognostic information.

  1. Measuring the Local Diffusion Coefficient with H.E.S.S. Observations of Very High-Energy Electrons

    Energy Technology Data Exchange (ETDEWEB)

    Hooper, Dan [Fermilab; Linden, Tim [Ohio State U., CCAPP

    2017-11-20

    The HAWC Collaboration has recently reported the detection of bright and spatially extended multi-TeV gamma-ray emission from Geminga, Monogem, and a handful of other nearby, middle-aged pulsars. The angular profile of the emission observed from these pulsars is surprising, in that it implies that cosmic-ray diffusion is significantly inhibited within ~25 pc of these objects, compared to the expectations of standard Galactic diffusion models. This raises the important question of whether the diffusion coefficient in the local interstellar medium is also low, or whether it is instead better fit by the mean Galactic value. Here, we utilize recent observations of the cosmic-ray electron spectrum (extending up to ~20 TeV) by the H.E.S.S. Collaboration to show that the local diffusion coefficient cannot be as low as it is in the regions surrounding Geminga and Monogem. Instead, we conclude that cosmic rays efficiently diffuse through the bulk of the local interstellar medium. Among other implications, this further supports the conclusion that pulsars significantly contribute to the observed positron excess.

  2. Diffusion-weighted MR imaging of the normal pancreas: reproducibility and variations of apparent diffusion coefficient measurement at 1.5- and 3.0-Tesla.

    Science.gov (United States)

    Barral, M; Soyer, P; Ben Hassen, W; Gayat, E; Aout, M; Chiaradia, M; Rahmouni, A; Luciani, A

    2013-04-01

    To evaluate reproducibility and variations in apparent diffusion coefficient (ADC) measurement in normal pancreatic parenchyma at 1.5- and 3.0-Tesla and determine if differences may exist between the four pancreatic segments. Diffusion-weighted MR imaging of the pancreas was performed at 1.5-Tesla in 20 patients and at 3.0-Tesla in other 20 patients strictly matched for gender and age using the same b values (0, 400 and 800s/mm(2)). Two independent observers placed regions of interest within the four pancreatic segments to measure ADC at both fields. Intra- and inter-observer agreement in ADC measurement was assessed using Bland-Altman analysis and comparison between ADC values obtained at both fields using non-parametrical tests. There were no significant differences in ADC between repeated measurements and between ADC obtained at 1.5-Tesla and those at 3.0-Tesla. The 95% limits of intra-observer agreement between ADC were 2.3%-22.7% at 1.5-Tesla and 1%-24.2% at 3.0-Tesla and those for inter-observer agreement between 1.9%-14% at 1.5-Tesla and 8%-25% at 3.0-Tesla. ADC values were similar in all pancreatic segments at 3.0-T whereas the tail had lower ADC at 1.5-Tesla. ADC measurement conveys high degrees of intra- and inter-observer reproducibility. ADC have homogeneous distribution among the four pancreatic segments at 3.0-Tesla. Copyright © 2012 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  3. Identification of the primary motor cortex: value of T2 echo-planar imaging, diffusion-weighted imaging and quantitative apparent diffusion coefficient measurement at 3 T

    International Nuclear Information System (INIS)

    Dincer, Alp; Erzen, Canan; Oezyurt, Onur; Pamir, M.N.

    2010-01-01

    To investigate the primary motor cortex (PMC) concerning T2 shortening on T2 echo-planar imaging (EPI-T2) and the double-layer sign on diffusion-weighted imaging (DWI), and also to measure its apparent diffusion coefficient (ADC). 3-T MR DWI was performed in 134 adult volunteers and 64 patients. T2 shortening was graded as hypointense or isointense compared with the signal of the superior frontal cortex (SFC). The double-layer sign of the PMC was graded as present or absent. Both findings (T2 shortening and double-layer sign) were evaluated independently by two authors. ADC of the PMC and the SFC were calculated using manually selected ROIs. T2 shortening was found in 131 adults and 62 patients by author 1 and in 132 adults and 61 patients by author 2 (κ = 0.96 and 0.91). The double-layer sign was found in 131 adults and 61 patients by author 1 and in 127 adults and 58 patients by author 2 (κ = 0.94 and 0.91). ADC values of the PMC and the SFC were different for all subjects (p < 0.01). T2 shortening and/or the double-layer sign on 3-T MR can be used to locate the PMC. The difference in ADC values between PMC and SFC is a distinguishing feature. (orig.)

  4. Role of the apparent diffusion coefficient measurement by diffusion weighted magnetic resonance imaging in the diagnosis of Fasciola hepatica in the liver

    International Nuclear Information System (INIS)

    Onur, M.R.; Cicekci, M.; Kayali, A.; Aygun, C.; Kocakoc, E.

    2011-01-01

    The aim of this study was to investigate the diagnostic role of the apparent diffusion coefficient (ADC) measurement in the diagnosis of focal parenchymal lesions and to understand the discriminating role of the ADC value for differentiating Fasciola lesions from other focal liver lesions. We measured ADC values of parenchymal lesions and liver parenchyma in 18 patients with Fasciola hepatica infestation at b 100, b 600, and b 1000 s/mm 2 gradients. We further measured average ADC values of hepatic metastases (n=21), hepatocellular carcinomas (n=21), cholangiocarcinomas (n=7), hydatid cysts (n=12), and focal nodular hyperplasia (FNH) (n=12) and compared them with average ADC values for Fasciola hepatica. The differences between average ADC values of lesions (2.16±0.36 x 10 -3 mm 2 /s) and parenchyma (1.64±0.2 x 10 -3 mm 2 /s) at three gradients were statistically significant (P<0.05). Mean ADC values of Fasciola hepatica lesions were significantly different from most of the other focal hepatic lesions, except FNH at all gradients and hydatid cyst at only the b 100 gradient. ADC measurement may be a complementary method in the diagnosis of Fasciola hepatica, and it may be used to differentiate these lesions from other focal liver lesions. (author)

  5. Apparent diffusion coefficient measurement of ovarian stroma: A potential tool for the diagnosis of polycystic ovary syndrome.

    Science.gov (United States)

    Samanci, C; Alis, D; Ustabasioglu, F E; Ozmen, E; Ucar, A K; Aslan, M; Habibi, H A; Bakan, S; Ozcabi, B; Evliyaoğlu, S O; Adaletli, I

    2017-01-01

    The purpose of this study was to assess the diagnostic value of measuring the apparent diffusion coefficient (ADC) of ovarian stroma in polycystic ovary syndrome (PCOS). This study was approved by the institutional review board and informed consent was obtained from each women. A total of 17 women (mean age, 22.2 years±5.1 [SD]; range, 16-33 years) with a diagnosis of PCOS according to the Androgen Excess and PCOS Society criteria and 18 healthy women (mean age, 22.8 years±5.2 [SD]; range, 16-31 years) who served as a control group were included in this prospective study. ADC values of the ovarian stroma during the early follicular phase were calculated by two observers in the two groups. Comparisons were performed using the Student t-test. The mean ADC value in woman with PCOS (1.29±0.27×10 -3  mm 2 /s; range: 0.59×10 -3 - 1.88×10 -3  mm 2 /s) was significantly lower than that in the control group (1.48±0.17×10 -3 mm 2 /s; range: 1.12×10 -3 - 1.86×10 -3 mm 2 /s) (Povarian stroma are lower in patients with PCOS than in control subjects. ADC measurement of ovarian stroma in women with PCOS might help improve the diagnosis of PCOS. Copyright © 2016 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  6. A novel multiple headspace extraction gas chromatographic method for measuring the diffusion coefficient of methanol in water and in olive oil.

    Science.gov (United States)

    Zhang, Chun-Yun; Chai, Xin-Sheng

    2015-03-13

    A novel method for the determination of the diffusion coefficient (D) of methanol in water and olive oil has been developed. Based on multiple headspace extraction gas chromatography (MHE-GC), the methanol released from the liquid sample of interest in a closed sample vial was determined in a stepwise fashion. A theoretical model was derived to establish the relationship between the diffusion coefficient and the GC signals from MHE-GC measurements. The results showed that the present method has an excellent precision (RSDwater and olive oil, when compared with data reported in the literature. The present method is simple and practical and can be a valuable tool for the determination of the diffusion coefficient of volatile analyte(s) into food simulants from food and beverage packaging material, both in research studies and in actual applications. Copyright © 2015 Elsevier B.V. All rights reserved.

  7. Radiation measurement and inverse analysis techniques applied on the determination of the apparent mass diffusion coefficient for diverse contaminants and soil samples

    International Nuclear Information System (INIS)

    Rey Silva, D.V.F.M.; Oliveira, A.P.; Macacini, J.F.; Da Silva, N.C.; Cipriani, M.; Quinelato, A.L.

    2005-01-01

    Full text of publication follows: The study of the dispersion of radioactive materials in soils and in engineering barriers plays an important role in the safety analysis of nuclear waste repositories. In order to proceed with such kind of study the involved physical properties must be determined with precision, including the apparent mass diffusion coefficient, which is defined as the ratio between the effective mass diffusion coefficient and the retardation factor. Many different experimental and estimation techniques are available on the literature for the identification of the diffusion coefficient and this work describes the implementation of that developed by Pereira et al [1]. This technique is based on non-intrusive radiation measurements and the experimental setup consists of a cylindrical column filled with compacted media saturated with water. A radioactive contaminant is mixed with a portion of the media and then placed in the bottom of the column. Therefore, the contaminant will diffuse through the uncontaminated media due to the concentration gradient. A radiation detector is used to measure the number of counts, which is associated to the contaminant concentration, at several positions along the column during the experiment. Such measurements are then used to estimate the apparent diffusion coefficient of the contaminant in the porous media by inverse analysis. The inverse problem of parameter estimation is solved with the Levenberg-Marquart Method of minimization of the least-square norm. The experiment was optimized with respect to the number of measurement locations, frequency of measurements and duration of the experiment through the analysis of the sensitivity coefficients and by using a D-optimum approach. This setup is suitable for studying a great number of combinations of diverse contaminants and porous media varying in composition and compacting, with considerable easiness and reliable results, and it was chosen because that is the

  8. Determination of the diffusion coefficient of hydrogen ion in hydrogels.

    Science.gov (United States)

    Schuszter, Gábor; Gehér-Herczegh, Tünde; Szűcs, Árpád; Tóth, Ágota; Horváth, Dezső

    2017-05-17

    The role of diffusion in chemical pattern formation has been widely studied due to the great diversity of patterns emerging in reaction-diffusion systems, particularly in H + -autocatalytic reactions where hydrogels are applied to avoid convection. A custom-made conductometric cell is designed to measure the effective diffusion coefficient of a pair of strong electrolytes containing sodium ions or hydrogen ions with a common anion. This together with the individual diffusion coefficient for sodium ions, obtained from PFGSE-NMR spectroscopy, allows the determination of the diffusion coefficient of hydrogen ions in hydrogels. Numerical calculations are also performed to study the behavior of a diffusion-migration model describing ionic diffusion in our system. The method we present for one particular case may be extended for various hydrogels and diffusing ions (such as hydroxide) which are relevant e.g. for the development of pH-regulated self-healing mechanisms and hydrogels used for drug delivery.

  9. Diffusion Coefficients of Several Aqueous Alkanolamine Solutions

    NARCIS (Netherlands)

    Snijder, Erwin D.; Riele, Marcel J.M. te; Versteeg, Geert F.; Swaaij, W.P.M. van

    1993-01-01

    The Taylor dispersion technique was applied for the determination of diffusion coefficients of various systems. Experiments with the system KCl in water showed that the experimental setup provides accurate data. For the alkanolamines monoethanolamine (MEA), diethanolamine (DEA), methyldiethanolamine

  10. Molecular Diffusion Coefficients: Experimental Determination and Demonstration.

    Science.gov (United States)

    Fate, Gwendolyn; Lynn, David G.

    1990-01-01

    Presented are laboratory methods which allow the demonstration and determination of the diffusion coefficients of compounds ranging in size from water to small proteins. Included are the procedures involving the use of a spectrometer, UV cell, triterated agar, and oxygen diffusion. Results including quantification are described. (CW)

  11. Problems with Discontinuous Diffusion/Dispersion Coefficients

    Directory of Open Access Journals (Sweden)

    Stefano Ferraris

    2012-01-01

    accurate on smooth solutions and based on a special numerical treatment of the diffusion/dispersion coefficients that makes its application possible also when such coefficients are discontinuous. Numerical experiments confirm the convergence of the numerical approximation and show a good behavior on a set of benchmark problems in two space dimensions.

  12. SU-F-303-13: Initial Evaluation of Four Dimensional Diffusion- Weighted MRI (4D-DWI) and Its Effect On Apparent Diffusion Coefficient (ADC) Measurement

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Y [Duke University Medical Physics Program (United States); Yin, F; Czito, B; Bashir, M; Palta, M; Cai, J [Duke University Medical Center, Durham, NC (United States); Zhong, X; Dale, B [Siemens Healthcare, Durham, NC (United States)

    2015-06-15

    Purpose: Diffusion-weighted imaging(DWI) has been shown to have superior tumor-to-tissue contrast for cancer detection.This study aims at developing and evaluating a four dimensional DWI(4D-DWI) technique using retrospective sorting method for imaging respiratory motion for radiotherapy planning,and evaluate its effect on Apparent Diffusion Coefficient(ADC) measurement. Materials/Methods: Image acquisition was performed by repeatedly imaging a volume of interest using a multi-slice single-shot 2D-DWI sequence in the axial planes and cine MRI(served as reference) using FIESTA sequence.Each 2D-DWI image were acquired in xyz-diffusion-directions with a high b-value(b=500s/mm2).The respiratory motion was simultaneously recorded using bellows.Retrospective sorting was applied in each direction to reconstruct 4D-DWI.The technique was evaluated using a computer simulated 4D-digital human phantom(XCAT),a motion phantom and a healthy volunteer under an IRB-approved study.Motion trajectories of regions-of-interests(ROI) were extracted from 4D-DWI and compared with reference.The mean motion trajectory amplitude differences(D) between the two was calculated.To quantitatively analyze the motion artifacts,XCAT were controlled to simulate regular motion and the motions of 10 liver cancer patients.4D-DWI,free-breathing DWI(FB- DWI) were reconstructed.Tumor volume difference(VD) of each phase of 4D-DWI and FB-DWI from the input static tumor were calculated.Furthermore, ADC was measured for each phase of 4D-DWI and FB-DWI data,and mean tumor ADC values(M-ADC) were calculated.Mean M-ADC over all 4D-DWI phases was compared with M-ADC calculated from FB-DWI. Results: 4D-DWI of XCAT,the motion phantom and the healthy volunteer demonstrated the respiratory motion clearly.ROI D values were 1.9mm,1.7mm and 2.0mm,respectively.For motion artifacts analysis,XCAT 4D-DWI images show much less motion artifacts compare to FB-DWI.Mean VD for 4D-WDI and FB-DWI were 8.5±1.4% and 108±15

  13. Determination of ion diffusion coefficients by the electromigration method

    International Nuclear Information System (INIS)

    Bonchev, G.D.; Milanov, M.V.; Bozhikov, G.A.; Ivanov, P.I.; Priemyshev, A.N.; Maslov, O.D.; Dmitriev, S.N.

    2003-01-01

    An electrophoretic method for measuring ion diffusion coefficients in aqueous solutions is developed. The value of the diffusion coefficient can be determined from the linear relationship between the square standard deviation of the electrophoretic zone and the time from the start of the diffusion process. Using the device for horizontal zone electrophoresis in a free electrolyte, a series of diffusion experiments are performed with no-carrier-added radionuclides in microconcentrations (10 -9 - 10 -10 M). Diffusion coefficients of 111 In(III), 175 Hf(IV) and 237 Pu(VI) ions at 25 0 C are determined in nitric acid media. Simultaneous determination of the diffusion coefficient and electrophoretic mobility allows one to calculate the effective charge of the investigated ions in accordance with the Nernst-Einstein law

  14. Diffusion and transport coefficients in synthetic opals

    International Nuclear Information System (INIS)

    Sofo, J. O.; Mahan, G. D.

    2000-01-01

    Opals are structures composed of close-packed spheres in the size range of nano to micrometers. They are sintered to create small necks at the points of contact. We have solved the diffusion problem in such structures. The relation between the diffusion coefficient and the thermal and electrical conductivity is used to estimate the transport coefficients of opal structures as a function of the neck size and the mean free path of the carriers. The theory presented is also applicable to the diffusion problem in other periodic structures. (c) 2000 The American Physical Society

  15. Local diffusion coefficient determination: Mediterranean Sea experiments

    International Nuclear Information System (INIS)

    Bacciola, D.; Borghini, M.; Cannarsa, S.

    1993-10-01

    The Mediterranean is a semi/enclosed basin characterized by the presence of channels and straits influencing the circulation, temperature and salinity fields. The tides generally have amplitudes of the order of 10 cm and velocities of few cm/s. Conversely, the wind forced circulation is very strong and can assume velocity values of 1 m/s at the sea surface. The temperature and salinity fields have a high temporal and spatial variability, because of many mixing processes existing in the sea. For example, the waters coming from the Provencal basin meet those waters coming from the Tyrrhenian Sea in the eastern Ligurian Sea, creating meanders and eddies. Local runoff influences significantly the coastal circulation. This paper describes diffusion experiments carried out in this complex environment. The experimental apparatus for the detection of the fluorescine released at sea was composed by two Turner mod. 450 fluorometres. During the experiments, temperature and salinity vertical profiles were measured by using a CTD; meteorological data were acquired on a dinghy. The positioning was obtained by means of a Motorola system, having a precision of about 1 meter. The experiments were carried out under different stratification and wind conditions. From data analysis it was found that the horizontal diffusion coefficient does not depend on time or boundary conditions. The role of stratification is important with regard to vertical displacement of the dye. However, its role with regard to vertical diffusion cannot be assessed with the actual experimental apparatus

  16. Diffusion coefficient, porosity measurement, dynamic and equilibrium swelling studies of Acrylic acid/Polyvinyl alcohol (AA/PVA hydrogels

    Directory of Open Access Journals (Sweden)

    Nazar Mohammad Ranjha

    2015-06-01

    Full Text Available Objective of the present work was to synthesize hydrogels of acrylic acid/polyvinyl alcohol (AA/PVA by free radical polymerization by using glutaradehyde (GA as crosslinkers. The hydrogels were evaluated for swelling, diffusion coefficient and network parameters like the average molecular weight between crosslink’s, polymer volume fraction in swollen state, number of repeating units between crosslinks and crosslinking density by using Flory-Huggins theory. It was found that the degree of swelling of AA/PVA hydrogels increases greatly within the pH range 5-7. The gel fraction and porosity increased by increasing the concentration of AA or PVA. Increase in degree of crosslinking, decreased the porosity and inverse was observed in gel fraction. Selected samples were loaded with metoprolol tartrate. Drug release was studied in USP hydrochloric acid solution of pH 1.2 and phosphate buffer solutions of pH 5.5 and 7.5. Various kinetics models like zero order, first order, Higuchi and Peppas model were used for in vitro kinetic studies. The results showed that the drug release followed concentration dependent effect (First order kinetics with non-Fickian diffusion. FTIR and SEM used to study the structure, crystallinity, compatibility, thermal stability and morphology of prepared and drug loaded hydrogels respectively.

  17. The solubility and diffusion coefficient of helium in uranium dioxide

    International Nuclear Information System (INIS)

    Nakajima, Kunihisa; Serizawa, Hiroyuki; Shirasu, Noriko; Haga, Yoshinori; Arai, Yasuo

    2011-01-01

    Highlights: ► The solubility and diffusivity of He in single-crystal UO 2 were determined. ► The determined He solubility lay within the scatter of the available data. ► The determined He diffusivity was in good agreement with recent experimental data. ► The He behavior was analyzed in terms of a simple interstitial diffusion mechanism. ► The experimental diffusivity was much lower than that analyzed theoretically. - Abstract: The solubility and diffusion coefficient of helium in the single-crystal UO 2 samples were determined by a Knudsen-effusion mass-spectrometric method. The measured helium solubilities were found to lie within the scatter of the available data, but to be much lower than those for the polycrystalline samples. The diffusion analysis was conducted based on a hypothetical equivalent sphere model and the simple Fick’s law. The helium diffusion coefficient was determined by using the pre-exponential factor and activation energy as the fitting parameters for the measured and calculated fractional releases of helium. The optimized diffusion coefficients were in good agreement with those obtained by a nuclear reaction method reported in the past. It was also found that the pre-exponential factors of the determined diffusion coefficients were much lower than those analyzed in terms of a simple interstitial diffusion mechanism.

  18. The determination of solubility and diffusion coefficient for solids in liquids by an inverse measurement technique using cylinders of amorphous glucose as a model compound

    International Nuclear Information System (INIS)

    Hu, Chengyao; Huang, Pei

    2011-01-01

    The importance of sugar and sugar-containing materials is well recognized nowadays, owing to their application in industrial processes, particularly in the food, pharmaceutical and cosmetic industries. Because of the large numbers of those compounds involved and the relatively small number of solubility and/or diffusion coefficient data for each compound available, it is highly desirable to measure the solubility and/or diffusion coefficient as efficiently as possible and to be able to improve the accuracy of the methods used. In this work, a new technique was developed for the measurement of the diffusion coefficient of a stationary solid solute in a stagnant solvent which simultaneously measures solubility based on an inverse measurement problem algorithm with the real-time dissolved amount profile as a function of time. This study differs from established techniques in both the experimental method and the data analysis. The experimental method was developed in which the dissolved amount of solid solute in quiescent solvent was investigated using a continuous weighing technique. In the data analysis, the hybrid genetic algorithm is used to minimize an objective function containing a calculated and a measured dissolved amount with time. This is measured on a cylindrical sample of amorphous glucose in methanol or ethanol. The calculated dissolved amount, that is a function of the unknown physical properties of the solid solute in the solvent, is calculated by the solution of the two-dimensional nonlinear inverse natural convection problem. The estimated values of the solubility of amorphous glucose in methanol and ethanol at 293 K were respectively 32.1 g/100 g methanol and 1.48 g/100 g ethanol, in agreement with the literature values, and support the validity of the simultaneously measured diffusion coefficient. These results show the efficiency and the stability of the developed technique to simultaneously estimate the solubility and diffusion coefficient. Also

  19. Lattice cell diffusion coefficients. Definitions and comparisons

    International Nuclear Information System (INIS)

    Hughes, R.P.

    1980-01-01

    Definitions of equivalent diffusion coefficients for regular lattices of heterogeneous cells have been given by several authors. The paper begins by reviewing these different definitions and the unification of their derivation. This unification makes clear how accurately each definition (together with appropriate cross-section definitions to preserve the eigenvalue) represents the individual reaction rates within the cell. The approach can be extended to include asymmetric cells and whereas before, the buckling describing the macroscopic flux shape was real, here it is found to be complex. A neutron ''drift'' coefficient as well as a diffusion coefficient is necessary to produce the macroscopic flux shape. The numerical calculation of the various different diffusion coefficients requires the solutions of equations similar to the ordinary transport equation for an infinite lattice. Traditional reactor physics codes are not sufficiently flexible to solve these equations in general. However, calculations in certain simple cases are presented and the theoretical results quantified. In difficult geometries, Monte Carlo techniques can be used to calculate an effective diffusion coefficient. These methods relate to those already described provided that correlation effects between different generations of neutrons are included. Again, these effects are quantified in certain simple cases. (author)

  20. Improved differentiation between hepatic hemangioma and metastases on diffusion-weighted MRI by measurement of standard deviation of apparent diffusion coefficient.

    Science.gov (United States)

    Hardie, Andrew D; Egbert, Robert E; Rissing, Michael S

    2015-01-01

    Diffusion-weighted magnetic resonance imaging (DW-MR) can be useful in the differentiation of hemangiomata from liver metastasis, but improved methods other than by mean apparent diffusion coefficient (mADC) are needed. A retrospective review identified 109 metastatic liver lesions and 86 hemangiomata in 128 patients who had undergone DW-MR. For each lesion, mADC and the standard deviation of the mean ADC (sdADC) were recorded and compared by receiver operating characteristic analysis. Mean mADC was higher in benign hemangiomata (1.52±0.12 mm(2)/s) than in liver metastases (1.33±0.18 mm(2)/s), but there was significant overlap in values. The mean sdADC was lower in hemangiomata (101±17 mm(2)/s) than metastases (245±25 mm(2)/s) and demonstrated no overlap in values, which was significantly different (P<.0001). Hemangiomata may be better able to be differentiated from liver metastases on the basis of sdADC than by mADC, although further studies are needed. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Simultaneous Measurement of T2 and Apparent Diffusion Coefficient (T2+ADC) in the Heart With Motion-Compensated Spin Echo Diffusion-Weighted Imaging

    Science.gov (United States)

    Aliotta, Eric; Moulin, Kévin; Zhang, Zhaohuan; Ennis, Daniel B.

    2018-01-01

    Purpose To evaluate a technique for simultaneous quantitative T2 and apparent diffusion coefficient (ADC) mapping in the heart (T2+ADC) using spin echo (SE) diffusion-weighted imaging (DWI). Theory and Methods T2 maps from T2+ADC were compared with single-echo SE in phantoms and with T2-prepared (T2-prep) balanced steady-state free precession (bSSFP) in healthy volunteers. ADC maps from T2+ADC were compared with conventional DWI in phantoms and in vivo. T2+ADC was also demonstrated in a patient with acute myocardial infarction (MI). Results Phantom T2 values from T2+ADC were closer to a single-echo SE reference than T2-prep bSSFP (−2.3 ± 6.0% vs 22.2 ± 16.3%; P T2 values from T2+ADC were significantly shorter than T2-prep bSSFP (35.8 ± 3.1 vs 46.8 ± 3.8 ms; P T2+ADC and conventional motion-compensated DWI (1.39 ± 0.18 vs 1.38 ± 0.18 mm2/ms; P = N.S.). In the patient, T2 and ADC were both significantly elevated in the infarct compared with remote myocardium (T2: 40.4 ± 7.6 vs 56.8 ± 22.0; P T2+ADC generated coregistered, free-breathing T2 and ADC maps in healthy volunteers and a patient with acute MI with no cost in accuracy, precision, or scan time compared with DWI. PMID:28516485

  2. Spatial Mapping of Translational Diffusion Coefficients Using Diffusion Tensor Imaging: A Mathematical Description.

    Science.gov (United States)

    Shetty, Anil N; Chiang, Sharon; Maletic-Savatic, Mirjana; Kasprian, Gregor; Vannucci, Marina; Lee, Wesley

    2014-01-01

    In this article, we discuss the theoretical background for diffusion weighted imaging and diffusion tensor imaging. Molecular diffusion is a random process involving thermal Brownian motion. In biological tissues, the underlying microstructures restrict the diffusion of water molecules, making diffusion directionally dependent. Water diffusion in tissue is mathematically characterized by the diffusion tensor, the elements of which contain information about the magnitude and direction of diffusion and is a function of the coordinate system. Thus, it is possible to generate contrast in tissue based primarily on diffusion effects. Expressing diffusion in terms of the measured diffusion coefficient (eigenvalue) in any one direction can lead to errors. Nowhere is this more evident than in white matter, due to the preferential orientation of myelin fibers. The directional dependency is removed by diagonalization of the diffusion tensor, which then yields a set of three eigenvalues and eigenvectors, representing the magnitude and direction of the three orthogonal axes of the diffusion ellipsoid, respectively. For example, the eigenvalue corresponding to the eigenvector along the long axis of the fiber corresponds qualitatively to diffusion with least restriction. Determination of the principal values of the diffusion tensor and various anisotropic indices provides structural information. We review the use of diffusion measurements using the modified Stejskal-Tanner diffusion equation. The anisotropy is analyzed by decomposing the diffusion tensor based on symmetrical properties describing the geometry of diffusion tensor. We further describe diffusion tensor properties in visualizing fiber tract organization of the human brain.

  3. Fractal diffusion coefficient from dynamical zeta functions

    Energy Technology Data Exchange (ETDEWEB)

    Cristadoro, Giampaolo [Max Planck Institute for the Physics of Complex Systems, Noethnitzer Str. 38, D 01187 Dresden (Germany)

    2006-03-10

    Dynamical zeta functions provide a powerful method to analyse low-dimensional dynamical systems when the underlying symbolic dynamics is under control. On the other hand, even simple one-dimensional maps can show an intricate structure of the grammar rules that may lead to a non-smooth dependence of global observables on parameters changes. A paradigmatic example is the fractal diffusion coefficient arising in a simple piecewise linear one-dimensional map of the real line. Using the Baladi-Ruelle generalization of the Milnor-Thurnston kneading determinant, we provide the exact dynamical zeta function for such a map and compute the diffusion coefficient from its smallest zero. (letter to the editor)

  4. Fractal diffusion coefficient from dynamical zeta functions

    International Nuclear Information System (INIS)

    Cristadoro, Giampaolo

    2006-01-01

    Dynamical zeta functions provide a powerful method to analyse low-dimensional dynamical systems when the underlying symbolic dynamics is under control. On the other hand, even simple one-dimensional maps can show an intricate structure of the grammar rules that may lead to a non-smooth dependence of global observables on parameters changes. A paradigmatic example is the fractal diffusion coefficient arising in a simple piecewise linear one-dimensional map of the real line. Using the Baladi-Ruelle generalization of the Milnor-Thurnston kneading determinant, we provide the exact dynamical zeta function for such a map and compute the diffusion coefficient from its smallest zero. (letter to the editor)

  5. Diffusion coefficient calculations for cylindrical cells

    International Nuclear Information System (INIS)

    Lam-Hime, M.

    1983-03-01

    An accurate and general diffusion coefficient calculation for cylindrical cells is described using isotropic scattering integral transport theory. This method has been particularly applied to large regular lattices of graphite-moderated reactors with annular coolant channels. The cells are divided into homogeneous zones, and a zone-wise flux expansion is used to formulate a collision probability problem. The reflection of neutrons at the cell boundary is accounted for by the conservation of the neutron momentum. The uncorrected diffusion coefficient Benoist's definition is used, and the described formulation does not neglect any effect. Angular correlation terms, energy coupling non-uniformity and anisotropy of the classical flux are exactly taken into account. Results for gas-graphite typical cells are given showing the importance of these approximations

  6. Verifying reciprocal relations for experimental diffusion coefficients in multicomponent mixtures

    DEFF Research Database (Denmark)

    Medvedev, Oleg; Shapiro, Alexander

    2003-01-01

    The goal of the present study is to verify the agreement of the available data on diffusion in ternary mixtures with the theoretical requirement of linear non-equilibrium thermodynamics consisting in symmetry of the matrix of the phenomenological coefficients. A common set of measured diffusion...... coefficients for a three-component mixture consists of four Fickian diffusion coefficients, each being reported separately. However, the Onsager theory predicts the existence of only three independent coefficients, as one of them disappears due to the symmetry requirement. Re-calculation of the Fickian...... extended sets of experimental data and reliable thermodynamic models were available. The sensitivity of the symmetry property to different thermodynamic parameters of the models was also checked. (C) 2003 Elsevier Science B.V. All rights reserved....

  7. Effective diffusion coefficients and porosity values for argillaceous rocks and bentonite: measured and estimated values for the provisional safety analyses for SGT-E2

    International Nuclear Information System (INIS)

    Van Loon, L.R.

    2014-11-01

    In Stage 2 of the Sectoral Plan for Deep Geological Repositories, safety analyses have to be performed. Geochemical parameters describing the transport and retardation of radionuclides in the argillaceous rocks considered and in compacted bentonite are required. In the present report, diffusion parameters for all clay host rocks, confining units and compacted bentonite are derived. Diffusion of tritiated water (HTO), "3"6Cl"- and "2"2Na"+ was studied. The measurements gave values for effective diffusion coefficients (D_e) and diffusion accessible porosities. The general observed trend "N"aD_e > "H"T"OD_e > "C"lD_e is in agreement with the expected behaviour of the three species in clay materials: ion exchanging cations show an enhanced mobility due to surface diffusion effects and anions are slowed down due to anion exclusion. Due to the negatively charged clay surfaces, anionic species are repelled from these surfaces resulting in an accessible porosity that is smaller than the total porosity as measured with HTO. The effect of porewater composition on the diffusion of HTO, "3"6Cl"- and "2"2Na"+ in Opalinus Clay was investigated. For ionic strength (IS) values between 0.17 M and 1.07 M, no significant effect on D_e could be observed. In the case of "3"6Cl"-, no effect on the accessible porosity was observed. The anion diffusion accessible porosity equals 50-60 % of the total porosity, independent on the ionic strength of the porewater. The diffusion parameters were measured on sedimentary rocks such as chalk, clay and limestone rocks. All data could be described by one single modified version of Archie's relation (extended Archie's relation). For values of porosity greater than about 0.1, the classical Archie's relation was valid. For values smaller than 0.1, the data deviated from the classical Archie's relation; this can be explained by additional changes of tortuosity with porosity values. At high porosity values (low density rocks), the microfabric of the clay

  8. Apparent diffusion coefficient measurements of bilateral kidneys at 3 T MRI: Effects of age, gender, and laterality in healthy adults

    International Nuclear Information System (INIS)

    Suo, S.-T.; Cao, M.-Q.; Ding, Y.-Z.; Yao, Q.-Y.; Wu, G.-Y.; Xu, J.-R.

    2014-01-01

    Aim: To investigate the effects of age and gender on apparent diffusion coefficient (ADC) measurements of bilateral kidneys at 3 T MRI, and compare the ADC values of left and right kidneys. Materials and methods: In all, 137 healthy participants (mean age 42.8 ± 14.7 years; age range 16–75 years) comprising 68 male and 69 female participants were enrolled. Three Tesla echo-planar diffusion-weighted imaging (DWI) of bilateral kidneys was performed and ADC values were measured in the cortex, medulla, and whole parenchyma. Pearson correlation analysis and linear regression were performed to determine the associations between the ADC values in each region and age. Effects of age and gender on ADC values were analysed using two-factor analysis of variance (ANOVA). The paired-samples t-test was established to compare the ADC values between left and right kidneys. Results: ADC values were significantly higher in the young group (≤50 years) than in the old group (>50 years), and correlated inversely with the age in all regions. Male participants had higher ADC values than female participants in all regions except left medulla. Two-factor ANOVA of age × gender showed no significant interactions between the variables age and gender were found. No significant differences in ADC values between left and right kidneys were observed. Conclusion: Renal ADC values are age- and gender-dependent, and show no significant difference between left and right kidneys. Age- and gender-related effects should be taken into consideration in future renal DWI studies when using normal ADC values from health controls. - Highlights: • Renal apparent diffusion coefficient (ADC) values decrease with ageing. • Men tend to have higher renal ADC values than women. • Bilateral kidneys seem to have no significantly different ADC values

  9. Measurement of the ferric diffusion coefficient in agarose and gelatine gels by utilization of the evolution of a radiation induced edge as reflected in relaxation rate images

    International Nuclear Information System (INIS)

    Pedersen, Torje V.; Olsen, Dag R.; Skretting, Arne

    1997-01-01

    A method has been developed to determine the diffusion coefficients of ferric ions in ferrous sulphate doped gels. A radiation induced edge was created in the gel, and two spin-echo sequences were used to acquire a pair of images of the gel at different points of time. For each of these image pairs, a longitudinal relaxation rate image was derived. From profiles through these images, the standard deviations of the Gaussian functions that characterize diffusion were determined. These data provided the basis for the determination of the ferric diffusion coefficients by two different methods. Simulations indicate that the use of single spin-echo images in this procedure may in some cases lead to a significant underestimation of the diffusion coefficient. The technique was applied to different agarose and gelatine gels that were prepared, irradiated and imaged simultaneously. The results indicate that the diffusion coefficient is lower in a gelatine gel than in an agarose gel. Addition of xylenol orange to a gelatine gel lowers the diffusion coefficient from 1.45 to 0.81 mm 2 h -1 , at the cost of significantly lower R 1 sensitivity. The addition of benzoic acid to the latter gel did not increase the R 1 sensitivity. (author) OK

  10. Measuring of heat transfer coefficient

    DEFF Research Database (Denmark)

    Henningsen, Poul; Lindegren, Maria

    Subtask 3.4 Measuring of heat transfer coefficient Subtask 3.4.1 Design and setting up of tests to measure heat transfer coefficient Objective: Complementary testing methods together with the relevant experimental equipment are to be designed by the two partners involved in order to measure...... the heat transfer coefficient for a wide range of interface conditions in hot and warm forging processes. Subtask 3.4.2 Measurement of heat transfer coefficient The objective of subtask 3.4.2 is to determine heat transfer values for different interface conditions reflecting those typically operating in hot...

  11. A systematic determination of diffusion coefficients of trace elements in open and restricted diffusive layers used by the diffusive gradients in a thin film technique

    DEFF Research Database (Denmark)

    Shiva, Amir Houshang; Teasdale, Peter R.; Bennett, William W.

    2015-01-01

    A systematic comparison of the diffusion coefficients of cations (Al, Cd, Co, Cu, Mn, Ni, Pb, Zn) and oxyanions (Al, As, Mo, Sb, V, W) in open (ODL) and restricted (RDL) diffusive layers used by the DGT technique was undertaken. Diffusion coefficients were measured using both the diffusion cell...... concentrations required with the Dcell measurements. This is the first time that D values have been reported for several oxyanions using RDL. Except for Al at pH 8.30 with ODL, all DDGT measurements were retarded relative to diffusion coefficients in water (DW) for both diffusive hydrogels. Diffusion in RDL...

  12. Devising a measuring system for the determination of diffusion coefficients in biofilm; Entwicklung eines Messsystems zur Bestimmung von Diffusionskoeffizienten im Biofilm

    Energy Technology Data Exchange (ETDEWEB)

    Berndt, K. [Fachhochschule Magdeburg (Germany). Fachbereich Chemie; Horn, H. [Fachhochschule Magdeburg (Germany). Hydro- und Abfallchemie

    1999-07-01

    The diffusion coefficient of a substrate in a biofilm is an important parameter for simulating mass turnover and transport in biofilm systems. The described method permits determining the diffusion coefficients in biofilms grown under defined substrate and hydrodynamic conditions in a laboratory reactor. (orig.) [German] Der Diffusionskoeffizient des Substrats in Biofilmen ist ein wichtiger Parameter fuer die Simulation von Stoffwechsel und -transport in Biofilmsystemen. Die dargestellte Methode erlaubt die Bestimmung des Diffusionskoeffizienten in Biofilmen, die unter definierten Substrat- und hydrodynamischen Bedingungen in einem Laborreaktor gewachsen sind. (orig.)

  13. The relationship between the apparent diffusion coefficient measured by magnetic resonance imaging, anoxic depolarization, and glutamate efflux during experimental cerebral ischemia.

    Science.gov (United States)

    Harris, N G; Zilkha, E; Houseman, J; Symms, M R; Obrenovitch, T P; Williams, S R

    2000-01-01

    A reduction in the apparent diffusion coefficient (ADC) of water measured by magnetic resonance imaging (MRI) has been shown to occur early after cerebrovascular occlusion. This change may be a useful indicator of brain tissue adversely affected by inadequate blood supply. The objective of this study was to test the hypothesis that loss of membrane ion homeostasis and depolarization can occur simultaneously with the drop in ADC. Also investigated was whether elevation of extracellular glutamate ([GLU]e) would occur before ADC changes. High-speed MRI of the trace of the diffusion tensor (15-second time resolution) was combined with simultaneous recording of the extracellular direct current (DC) potential and on-line [GLU]e from the striatum of the anesthetized rat. After a control period, data were acquired during remote middle cerebral artery occlusion for 60 minutes, followed by 30 minutes of reperfusion, and cardiac arrest-induced global ischemia. After either focal or global ischemia, the ADC was reduced by 10 to 25% before anoxic depolarization occurred. After either insult, the time for half the maximum change in ADC was significantly shorter than the corresponding DC potential parameter (P potential and did not peak until much later after either ischemic insult. This study demonstrates that ADC changes can occur before membrane depolarization and that high [GLU]e has no involvement in the early rapid ADC decrease.

  14. An axisymmetric diffusion experiment for the determination of diffusion and sorption coefficients of rock samples.

    Science.gov (United States)

    Takeda, M; Hiratsuka, T; Ito, K; Finsterle, S

    2011-04-25

    Diffusion anisotropy is a critical property in predicting migration of substances in sedimentary formations with very low permeability. The diffusion anisotropy of sedimentary rocks has been evaluated mainly from laboratory diffusion experiments, in which the directional diffusivities are separately estimated by through-diffusion experiments using different rock samples, or concurrently by in-diffusion experiments in which only the tracer profile in a rock block is measured. To estimate the diffusion anisotropy from a single rock sample, this study proposes an axisymmetric diffusion test, in which tracer diffuses between a cylindrical rock sample and a surrounding solution reservoir. The tracer diffusion between the sample and reservoir can be monitored from the reservoir tracer concentrations, and the tracer profile could also be obtained after dismantling the sample. Semi-analytical solutions are derived for tracer concentrations in both the reservoir and sample, accounting for an anisotropic diffusion tensor of rank two as well as the dilution effects from sampling and replacement of reservoir solution. The transient and steady-state analyses were examined experimentally and numerically for different experimental configurations, but without the need for tracer profiling. These experimental configurations are tested for in- and out-diffusion experiments using Koetoi and Wakkanai mudstones and Shirahama sandstone, and are scrutinized by a numerical approach to identify favorable conditions for parameter estimation. The analysis reveals the difficulty in estimating diffusion anisotropy; test configurations are proposed for enhanced identifiability of diffusion anisotropy. Moreover, it is demonstrated that the axisymmetric diffusion test is efficient in obtaining the sorption parameter from both steady-state and transient data, and in determining the effective diffusion coefficient if isotropic diffusion is assumed. Moreover, measuring reservoir concentrations in an

  15. An asixymmetric diffusion experiment for the determination of diffusion and sorption coefficients of rock samples

    Energy Technology Data Exchange (ETDEWEB)

    Takeda, M.; Hiratsuka, T.; Ito, K.; Finsterle, S.

    2011-02-01

    Diffusion anisotropy is a critical property in predicting migration of substances in sedimentary formations with very low permeability. The diffusion anisotropy of sedimentary rocks has been evaluated mainly from laboratory diffusion experiments, in which the directional diffusivities are separately estimated by through-diffusion experiments using different rock samples, or concurrently by in-diffusion experiments in which only the tracer profile in a rock block is measured. To estimate the diffusion anisotropy from a single rock sample, this study proposes an axisymmetric diffusion test, in which tracer diffuses between a cylindrical rock sample and a surrounding solution reservoir. The tracer diffusion between the sample and reservoir can be monitored from the reservoir tracer concentrations, and the tracer profile could also be obtained after dismantling the sample. Semi-analytical solutions are derived for tracer concentrations in both the reservoir and sample, accounting for an anisotropic diffusion tensor of rank two as well as the dilution effects from sampling and replacement of reservoir solution. The transient and steady-state analyses were examined experimentally and numerically for different experimental configurations, but without the need for tracer profiling. These experimental configurations are tested for in- and out-diffusion experiments using Koetoi and Wakkanai mudstones and Shirahama sandstone, and are scrutinized by a numerical approach to identify favorable conditions for parameter estimation. The analysis reveals the difficulty in estimating diffusion anisotropy; test configurations are proposed for enhanced identifiability of diffusion anisotropy. Moreover, it is demonstrated that the axisymmetric diffusion test is efficient in obtaining the sorption parameter from both steady-state and transient data, and in determining the effective diffusion coefficient if isotropic diffusion is assumed. Moreover, measuring reservoir concentrations in an

  16. Measuring localization and diffusion coefficients of basolateral proteins in lateral versus basal membranes using functionalized substrates and kICS analysis

    DEFF Research Database (Denmark)

    Marlar, Saw; Christensen, Eva Arnspang; Pedersen, Gitte Albinus

    2014-01-01

    Micropatterning enabled semiquantitation of basolateral proteins in lateral and basal membranes of the same cell. Lateral diffusion coefficients of basolateral aquaporin-3 (AQP3-EGFP) and EGFP-AQP4 were extracted from “lateral” and “basal” membranes using identical live-cell imaging and k...

  17. Stochastic Modelling of the Diffusion Coefficient for Concrete

    DEFF Research Database (Denmark)

    Thoft-Christensen, Palle

    In the paper, a new stochastic modelling of the diffusion coefficient D is presented. The modelling is based on physical understanding of the diffusion process and on some recent experimental results. The diffusion coefficients D is strongly dependent on the w/c ratio and the temperature....

  18. Simultaneous measurement of thermal diffusivity and effective infrared absorption coefficient in IR semitransparent and semiconducting n-CdMgSe crystals using photothermal radiometry

    Energy Technology Data Exchange (ETDEWEB)

    Pawlak, M., E-mail: mpawlak@fizyka.umk.pl [Institute of Physics, Faculty of Physics, Astronomy and Informatics, Nicolaus Copernicus University, Grudziądzka 5/7, Toruń (Poland); Maliński, M. [Department of Electronics and Computer Science, Koszalin University of Technology, 2 Śniadeckich St., Koszalin 75-453 (Poland)

    2015-01-10

    Highlights: • The new method of determination of the effective infrared absorption coefficient is presented. • The method can be used for transparent samples for the excitation radiation. • The effect of aluminum foil on the PTR signal in a transmission configuration is discussed. - Abstract: In this paper we propose a new procedure of simultaneous estimation of the effective infrared optical absorption coefficient and the thermal diffusivity of solid state samples using the photothermal infrared radiometry method in the transmission configuration. The proposed procedure relies on the analysis of the frequency dependent signal obtained from the samples covered with thin aluminum foil. This method can be applied for both optically opaque and transparent samples. The proposed method is illustrated with the results of the thermal diffusivity and the effective IR absorption coefficient obtained for several Cd{sub 1−x}Mg{sub x}Se crystals.

  19. New sensitive micro-measurements of dynamic surface tension and diffusion coefficients: Validated and tested for the adsorption of 1-Octanol at a microscopic air-water interface and its dissolution into water.

    Science.gov (United States)

    Kinoshita, Koji; Parra, Elisa; Needham, David

    2017-02-15

    Currently available dynamic surface tension (DST) measurement methods, such as Wilhelmy plate, droplet- or bubble-based methods, still have various experimental limitations such as the large size of the interface, convection in the solution, or a certain "dead time" at initial measurement. These limitations create inconsistencies for the kinetic analysis of surfactant adsorption/desorption, especially significant for ionic surfactants. Here, the "micropipette interfacial area-expansion method" was introduced and validated as a new DST measurement having a high enough sensitivity to detect diffusion controlled molecular adsorption at the air-water interfaces. To validate the new technique, the diffusion coefficient of 1-Octanol in water was investigated with existing models: the Ward Tordai model for the long time adsorption regime (1-100s), and the Langmuir and Frumkin adsorption isotherm models for surface excess concentration. We found that the measured diffusion coefficient of 1-Octanol, 7.2±0.8×10 -6 cm 2 /s, showed excellent agreement with the result from an alternative method, "single microdroplet catching method", to measure the diffusion coefficient from diffusion-controlled microdroplet dissolution, 7.3±0.1×10 -6 cm 2 /s. These new techniques for determining adsorption and diffusion coefficients can apply for a range of surface active molecules, especially the less-characterized ionic surfactants, and biological compounds such as lipids, peptides, and proteins. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Assessment of satellite derived diffuse attenuation coefficients ...

    Science.gov (United States)

    Optical data collected in coastal waters off South Florida and in the Caribbean Sea between January 2009 and December 2010 were used to evaluate products derived with three bio-optical inversion algorithms applied to MOIDS/Aqua, MODIS/Terra, and SeaWiFS satellite observations. The products included the diffuse attenuation coefficient at 490 nm (Kd_490) and for the visible range (Kd_PAR), and euphotic depth (Zeu, corresponding to 1% of the surface incident photosynthetically available radiation or PAR). Above-water hyperspectral reflectance data collected over optically shallow waters of the Florida Keys between June 1997 and August 2011 were used to help understand algorithm performance over optically shallow waters. The in situ data covered a variety of water types in South Florida and the Caribbean Sea, ranging from deep clear waters, turbid coastal waters, and optically shallow waters (Kd_490 range of ~0.03 – 1.29m-1). An algorithm based on Inherent Optical Properties (IOPs) showed the best performance (RMSD turbidity or shallow bottom contamination. Similar results were obtained when only in situ data were used to evaluate algorithm performance. The excellent agreement between satellite-derived remote sensing reflectance (Rrs) and in situ Rrs suggested that

  1. Diffusion coefficient of three-dimensional Yukawa liquids

    International Nuclear Information System (INIS)

    Dzhumagulova, K. N.; Ramazanov, T. S.; Masheeva, R. U.

    2013-01-01

    The purpose of this work is an investigation of the diffusion coefficient of the dust component in complex plasma. The computer simulation of the Yukawa liquids was made on the basis of the Langevin equation, which takes into account the influence of buffer plasma on the dust particles dynamics. The Green–Kubo relation was used to calculate the diffusion coefficient. Calculations of the diffusion coefficient for a wide range of the system parameters were performed. Using obtained numerical data, we constructed the interpolation formula for the diffusion coefficient. We also show that the interpolation formula correctly describes experimental data obtained under microgravity conditions

  2. Significance of apparent diffusion coefficient measurement for the differential diagnosis of multiple system atrophy, progressive supranuclear palsy, and Parkinson's disease: evaluation by 3.0-T MR imaging

    International Nuclear Information System (INIS)

    Tsukamoto, Kazumichi; Kanasaki, Yoshiko; Kakite, Suguru; Fujii, Shinya; Kaminou, Toshio; Ogawa, Toshihide; Matsusue, Eiji

    2012-01-01

    The clinical differentiation of Parkinson's disease (PD) from multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) may be challenging, especially in their early stages. The aim of this study was to evaluate the utility of apparent diffusion coefficient (ADC) measurement to distinguish among these degenerative disorders. Twenty-five MSA, 20 PSP, and 17 PD patients and 18 healthy controls were retrospectively studied. Axial diffusion-weighted and T2-weighted images were obtained using a 3-T MR system. Regions of interest (ROIs) were precisely placed in the midbrain, pons, putamen, globus pallidus, caudate nucleus, thalamus, superior cerebellar peduncle, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus, and the regional ADC (rADC) value was calculated in each ROI. In MSA, rADC values in the pons, middle cerebellar peduncle, cerebellar white matter, and cerebellar dentate nucleus were significantly higher than in PSP, PD, and controls. Furthermore, rADC values in the posterior putamen were significantly higher in MSA than in PSP and controls. In PSP, rADC values were significantly higher in the globus pallidus and midbrain than in MSA, PD, and controls. Furthermore, rADC values in the caudate nucleus and superior cerebellar peduncle were significantly higher in PSP than in MSA and controls. In PD, there were no significant differences in the rADC values compared to in MSA, PSP, and controls in all regions. Evaluation of rADC values in characteristic lesions in MSA, PSP, and PD by placing ROIs using 3-T systems can provide useful additional information for differentiating these disorders. (orig.)

  3. Solubility and diffusion coefficient of oxygen in silicon

    International Nuclear Information System (INIS)

    Itoh, Yoshiko; Nozaki, Tadashi

    1985-01-01

    The solubility and diffusion coefficient of oxygen in silicon between 1000 0 C and 1375 0 C were examined by charged particle activation analysis with the 16 O( 3 He,p) 18 F reaction, in which oxygen was activated with an equal probability over the depth of up to 250μm by a specially devised apparatus. Silicon wafers of known histories were heated in oxygen or argon for 12 to 473 hours, and the resultant oxygen depth profiles were determined by the activation, subsequent stepwise etching and 18 F activity measurement. The solubility thus obtained is given as 9.3 x 10 21 exp[-27.6kcal mol -1 /RT] at.cm -3 ; the diffusion coefficient has been found to be approximated as 3.2 exp[-67.1kcal mol -1 /RT] cm 2 s -1 over 1150 0 C, under which the apparent activation energy seems to decrease with decrease of temperature. (author)

  4. Apparent diffusion coefficient measurements in diffusion-weighted magnetic resonance imaging of the anterior mediastinum: inter-observer reproducibility of five different methods of region-of-interest positioning

    Energy Technology Data Exchange (ETDEWEB)

    Priola, Adriano Massimiliano; Priola, Sandro Massimo; Parlatano, Daniela; Gned, Dario; Veltri, Andrea [San Luigi Gonzaga University Hospital, Department of Diagnostic Imaging, Regione Gonzole 10, Orbassano, Torino (Italy); Giraudo, Maria Teresa [University of Torino, Department of Mathematics ' ' Giuseppe Peano' ' , Torino (Italy); Giardino, Roberto; Ardissone, Francesco [San Luigi Gonzaga University Hospital, Department of Thoracic Surgery, Regione Gonzole 10, Orbassano, Torino (Italy); Ferrero, Bruno [San Luigi Gonzaga University Hospital, Department of Neurology, Regione Gonzole 10, Orbassano, Torino (Italy)

    2017-04-15

    To investigate inter-reader reproducibility of five different region-of-interest (ROI) protocols for apparent diffusion coefficient (ADC) measurements in the anterior mediastinum. In eighty-one subjects, on ADC mapping, two readers measured the ADC using five methods of ROI positioning that encompassed the entire tissue (whole tissue volume [WTV], three slices observer-defined [TSOD], single-slice [SS]) or the more restricted areas (one small round ROI [OSR], multiple small round ROI [MSR]). Inter-observer variability was assessed with interclass correlation coefficient (ICC), coefficient of variation (CoV), and Bland-Altman analysis. Nonparametric tests were performed to compare the ADC between ROI methods. The measurement time was recorded and compared between ROI methods. All methods showed excellent inter-reader agreement with best and worst reproducibility in WTV and OSR, respectively (ICC, 0.937/0.874; CoV, 7.3 %/16.8 %; limits of agreement, ±0.44/±0.77 x 10{sup -3} mm{sup 2}/s). ADC values of OSR and MSR were significantly lower compared to the other methods in both readers (p < 0.001). The SS and OSR methods required less measurement time (14 ± 2 s) compared to the others (p < 0.0001), while the WTV method required the longest measurement time (90 ± 56 and 77 ± 49 s for each reader) (p < 0.0001). All methods demonstrate excellent inter-observer reproducibility with the best agreement in WTV, although it requires the longest measurement time. (orig.)

  5. Diffusion coefficient adaptive correction in Lagrangian puff model

    International Nuclear Information System (INIS)

    Tan Wenji; Wang Dezhong; Ma Yuanwei; Ji Zhilong

    2014-01-01

    Lagrangian puff model is widely used in the decision support system for nuclear emergency management. The diffusion coefficient is one of the key parameters impacting puff model. An adaptive method was proposed in this paper, which could correct the diffusion coefficient in Lagrangian puff model, and it aimed to improve the accuracy of calculating the nuclide concentration distribution. This method used detected concentration data, meteorological data and source release data to estimate the actual diffusion coefficient with least square method. The diffusion coefficient adaptive correction method was evaluated by Kincaid data in MVK, and was compared with traditional Pasquill-Gifford (P-G) diffusion scheme method. The results indicate that this diffusion coefficient adaptive correction method can improve the accuracy of Lagrangian puff model. (authors)

  6. Diffusion coefficients gases, dissolved in fluid of NPPs circulation contours

    International Nuclear Information System (INIS)

    Piontkovskij, A.I.

    2000-01-01

    In article is brought analysis of diverse gases diffusion coefficients computation methods, dissolved in liquid. On the basis of this analysis and treatment of being equalizations for concrete gases and certain parameters offers universal diffusion coefficients determination dependence for diverse gases in wide range of parameters, circulation contours typical for work NPP

  7. Monte Carlo based diffusion coefficients for LMFBR analysis

    International Nuclear Information System (INIS)

    Van Rooijen, Willem F.G.; Takeda, Toshikazu; Hazama, Taira

    2010-01-01

    A method based on Monte Carlo calculations is developed to estimate the diffusion coefficient of unit cells. The method uses a geometrical model similar to that used in lattice theory, but does not use the assumption of a separable fundamental mode used in lattice theory. The method uses standard Monte Carlo flux and current tallies, and the continuous energy Monte Carlo code MVP was used without modifications. Four models are presented to derive the diffusion coefficient from tally results of flux and partial currents. In this paper the method is applied to the calculation of a plate cell of the fast-spectrum critical facility ZEBRA. Conventional calculations of the diffusion coefficient diverge in the presence of planar voids in the lattice, but our Monte Carlo method can treat this situation without any problem. The Monte Carlo method was used to investigate the influence of geometrical modeling as well as the directional dependence of the diffusion coefficient. The method can be used to estimate the diffusion coefficient of complicated unit cells, the limitation being the capabilities of the Monte Carlo code. The method will be used in the future to confirm results for the diffusion coefficient obtained of the Monte Carlo code. The method will be used in the future to confirm results for the diffusion coefficient obtained with deterministic codes. (author)

  8. Imaging and assessment of diffusion coefficients by magnetic resonance

    International Nuclear Information System (INIS)

    Tintera, J.; Dezortova, M.; Hajek, M.; Fitzek, C.

    1999-01-01

    The problem of assessment of molecular diffusion by magnetic resonance is highlighted and some typical applications of diffusion imaging in the diagnosis, e.g., of cerebral ischemia, changes in patients with phenylketonuria or multiple sclerosis are discussed. The images were obtained by using diffusion weighted spin echo Echo-Planar Imaging sequence with subsequent correction of the geometrical distortion of the images and calculation of the Apparent Diffusion Coefficient map

  9. Effective diffusion coefficients of /sup 3/H/sub 2/O in several porous materials

    Energy Technology Data Exchange (ETDEWEB)

    Terashima, Y [Kyoto Univ. (Japan). Faculty of Engineering; Kumaki, T

    1976-12-01

    Diffusion coefficients of radionuclides in some porous structural materials and porous components of earth stratum are important as the basis for the safety evaluation of the storage and disposal of radioactive wastes. In our previous works, the method of analysis and experiment using a permeative type diffusion cell for measurement of effective diffusion coefficient was established, and experimental results were reported. In this paper, effective diffusion coefficients of /sup 3/H/sub 2/O in mortar, concrete, brick, clay layer, and sand layer were measured, and characteristics of these pore structure were discussed on the basis of tourtusity factor.

  10. Effective diffusion coefficients of 3H2O in several porous materials

    International Nuclear Information System (INIS)

    Terashima, Yutaka; Kumaki, Toru.

    1976-01-01

    Diffusion coefficients of radionuclides in some porous structural materials and porous components of earth stratum are important as the basis for the safety evaluation of the storage and disposal of radioactive wastes. In our previous works, the method of analysis and experiment using a permeative type diffusion cell for measurement of effective diffusion coefficient was established, and experimental results were reported. In this paper, effective diffusion coefficients of 3 H 2 O in mortar, concrete, brick, clay layer, and sand layer were measured, and characteristics of these pore structure were discussed on the basis of tourtusity factor. (auth.)

  11. Improved diffusion coefficients generated from Monte Carlo codes

    International Nuclear Information System (INIS)

    Herman, B. R.; Forget, B.; Smith, K.; Aviles, B. N.

    2013-01-01

    Monte Carlo codes are becoming more widely used for reactor analysis. Some of these applications involve the generation of diffusion theory parameters including macroscopic cross sections and diffusion coefficients. Two approximations used to generate diffusion coefficients are assessed using the Monte Carlo code MC21. The first is the method of homogenization; whether to weight either fine-group transport cross sections or fine-group diffusion coefficients when collapsing to few-group diffusion coefficients. The second is a fundamental approximation made to the energy-dependent P1 equations to derive the energy-dependent diffusion equations. Standard Monte Carlo codes usually generate a flux-weighted transport cross section with no correction to the diffusion approximation. Results indicate that this causes noticeable tilting in reconstructed pin powers in simple test lattices with L2 norm error of 3.6%. This error is reduced significantly to 0.27% when weighting fine-group diffusion coefficients by the flux and applying a correction to the diffusion approximation. Noticeable tilting in reconstructed fluxes and pin powers was reduced when applying these corrections. (authors)

  12. Determination of gas diffusion coefficients in undisturbed Boom clay

    International Nuclear Information System (INIS)

    Jacops, E.; Volckaert, G.; Maes, N.; Govaerts, J.; Weetjens, E.

    2012-01-01

    Document available in extended abstract form only. The Belgian agency for radioactive waste and enriched fissile materials Ondraf/Niras presently considers Boom Clay as a potential host formation for the disposal of high-level and long-lived radioactive waste. The production of gas is unavoidable within a geological repository. Gas is produced by different mechanisms: anaerobic corrosion of metals in waste and packaging, radiolysis of water and organic materials in the waste and engineered barriers and microbial degradation of various organic wastes. Corrosion and radiolysis yield mainly hydrogen while microbial degradation leads to methane and carbon dioxide. The gas generated in the near field of a geological repository will dissolve in the pore water and is transported away from the repository by diffusion as dissolved species. If the gas generation rate is larger than the diffusive flux, the pore water will become over-saturated and a free gas phase will form. Initially, isolated gas bubbles will accumulate until a continuous gas phase is formed. As gas pressure continues to increase, discrete gas pathways may be formed by tensile fractures within the rock fabric. Consequently, this entire process may locally and at least temporarily alter the hydraulic and mechanical properties of the engineered barriers and the clay and, perhaps, their performance. Therefore it is important to assess whether or not gas production rates might exceed the diffusive gas flux. The currently available gas diffusion parameters (D eff : effective diffusion coefficient) for hydrogen in Boom Clay, obtained from the MEGAS project, and re-evaluated after lead to an estimated D eff between 1.9 10 -12 and 1.5 10 -10 m 2 /s. Sensitivity calculations showed that this uncertainty on the diffusion coefficient, combined with that on the gas source term, made it impossible to exclude the formation of a free gas phase. To reduce the uncertainty, an experimental method was developed to determine

  13. Measurements of diagnostic examination performance using quantitative apparent diffusion coefficient and proton MR spectroscopic imaging in the preoperative evaluation of tumor grade in cerebral gliomas

    International Nuclear Information System (INIS)

    Server, Andres; Kulle, Bettina; Gadmar, Oystein B.; Josefsen, Roger; Kumar, Theresa; Nakstad, Per H.

    2011-01-01

    Purpose: Tumor grading is very important both in treatment decision and evaluation of prognosis. While tissue samples are obtained as part of most therapeutic approaches, factors that may result in inaccurate grading due to sampling error (namely, heterogeneity in tissue sampling, as well as tumor-grade heterogeneity within the same tumor specimen), have led to a desire to use imaging better to ascertain tumor grade. The purpose in our study was to evaluate the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), area under the curve (AUC), and accuracy of diffusion-weighted MR imaging (DWI), proton MR spectroscopic imaging (MRSI) or both in grading primary cerebral gliomas. Materials and methods: We performed conventional MR imaging (MR), DWI, and MRSI in 74 patients with newly diagnosed brain gliomas: 59 patients had histologically verified high-grade gliomas: 37 glioblastomas multiform (GBM) and 22 anaplastic astrocytomas (AA), and 15 patients had low-grade gliomas. Apparent diffusion coefficient (ADC) values of tumor and peritumoral edema, and ADC ratios (ADC in tumor or peritumoral edema to ADC of contralateral white matter, as well as ADC in tumor to ADC in peritumoral edema) were determined from three regions of interest. The average of the mean, maximum, and minimum for ADC variables was calculated for each patient. The metabolite ratios of Cho/Cr and Cho/NAA at intermediate TE were assessed from spectral maps in the solid portion of tumor, peritumoral edema and contralateral normal-appearing white matter. Tumor grade determined with the two methods was then compared with that from histopathologic grading. Logistic regression and receiver operating characteristic (ROC) curve analysis were performed to determine optimum thresholds for tumor grading. Measures of diagnostic examination performance, such as sensitivity, specificity, PPV, NPV, AUC, and accuracy for identifying high-grade gliomas were also calculated

  14. Calculation of ternary interdiffusion coefficients using a single diffusion couple

    Czech Academy of Sciences Publication Activity Database

    Čermák, Jiří; Rothová, Věra

    2016-01-01

    Roč. 54, č. 5 (2016), s. 305-314 ISSN 0023-432X R&D Projects: GA MŠk(CZ) ED1.1.00/02.0068 Institutional support: RVO:68081723 Keywords : diffusion * interdiffusion * ternary alloys * ternary diffusion coefficients Subject RIV: BJ - Thermodynamics Impact factor: 0.366, year: 2016

  15. Value of apparent diffusion coefficient (ADC) in evaluating response ...

    African Journals Online (AJOL)

    Objective. To determine whether the apparent diffusion coefficient (ADC) value obtained by diffusion-weighted magnetic resonance imaging (DW-MRI) can be used as a reliable detector of response of carcinoma of the cervix treated with chemoradiotherapy, compared with conventional. T2-weighted MRI. Design.

  16. Calculation of self-diffusion coefficients in iron

    Directory of Open Access Journals (Sweden)

    Baohua Zhang

    2014-01-01

    Full Text Available On the basis of available P-V-T equation of state of iron, the temperature and pressure dependence of self-diffusion coefficients in iron polymorphs (α, δ, γ and ɛ phases have been successfully reproduced in terms of the bulk elastic and expansivity data by means of a thermodynamical model that interconnects point defects parameters with bulk properties. The calculated diffusion parameters, such as self-diffusion coefficient, activation energy and activation volume over a broad temperature range (500-2500 K and pressure range (0-100 GPa, compare favorably well with experimental or theoretical ones when the uncertainties are considered.

  17. In situ measurement of diffusivity

    International Nuclear Information System (INIS)

    Berne, F.; Pocachard, J.

    2004-01-01

    The mechanism of molecular diffusion controls the migration of contaminants in very low-permeability porous media, like underground facilities for the storage of hazardous waste. Determining of relevant diffusion coefficients is therefore of prime importance. A few techniques exist for in situ measurement of the quantity, but they suffer from many handicaps (duration, complexity and cost of the experiments). We propose here two innovative methods that have some potential to improve the situation. So far, we have found them feasible on the basis of design calculations and laboratory experiments. This work is presently protected by a patent. (author)

  18. In situ measurement of diffusivity

    International Nuclear Information System (INIS)

    Berne, Ph.; Pocachard, J.

    2005-01-01

    The mechanism of molecular diffusion controls the migration of contaminants in very low-permeability porous media, like underground facilities for the storage of hazardous waste. Determining the relevant diffusion coefficients is, therefore, of prime importance. A few techniques exist for the in situ measurement of that quantity, but they suffer from many handicaps (duration, complexity and cost of the experiments). We propose here two innovative methods that have some potential to improve this situation. So far, we have found them feasible on the basis of design calculations and laboratory experiments. This work is presently protected by a patent. (author)

  19. Effective diffusion coefficients of DNAPL waste components in saturated low permeability soil materials

    Science.gov (United States)

    Ayral-Cinar, Derya; Demond, Avery H.

    2017-12-01

    Diffusion is regarded as the dominant transport mechanism into and out of low permeable subsurface lenses and layers in the subsurface. But, some reports of mass storage in such zones are higher than what might be attributable to diffusion, based on estimated diffusion coefficients. Despite the importance of diffusion to efforts to estimate the quantity of residual contamination in the subsurface, relatively few studies present measured diffusion coefficients of organic solutes in saturated low permeability soils. This study reports the diffusion coefficients of a trichloroethylene (TCE), and an anionic surfactant, Aerosol OT (AOT), in water-saturated silt and a silt-montmorillonite (25:75) mixture, obtained using steady-state experiments. The relative diffusivity ranged from 0.11 to 0.17 for all three compounds for the silt and the silt-clay mixture that was allowed to expand. In the case in which the swelling was constrained, the relative diffusivity was about 0.07. In addition, the relative diffusivity of 13C-labeled TCE through a water saturated silt-clay mixture that had contacted a field dense non-aqueous phase liquid (DNAPL) for 18 months was measured and equaled 0.001. These experimental results were compared with the estimates generated using common correlations, and it was found that, in all cases, the measured diffusion coefficients were significantly lower than the estimated. Thus, the discrepancy between mass accumulations observed in the field and the mass storage that can attributable to diffusion may be greater than previously believed.

  20. Diffusion coefficients of decay products of radon and thoron

    International Nuclear Information System (INIS)

    Raghunath, B.; Kotrappa, P.

    1979-01-01

    The diffusion coefficients of the decay products of radon and thoron have relevance in the evaluation of inhalation hazards in uranium and thorium processing industries. A recently developed diffusion sampler, based on Mercer's theory of diffusional deposition between the concentric circular plates, has been used for determining the diffusion coefficients of the unattached decay products of radon and thoron (RaA, RaB, RaC and ThB). Experiments were conducted at different ventilation rates (6 and 60 changes/hr) at different relative humidities (10 and 90%) and both in air and argon atmospheres. Diffusion coefficients were found to increase with increasing ventilation rates and were found to decrease at higher relative humidities, the effect being more marked at lower ventilation rates. Both of these effects were less pronounced in argon than in air. Results are discussed in light of the known properties of these decay products. (author)

  1. Anomalous behavior of the diffusion coefficient in thin active films

    International Nuclear Information System (INIS)

    Basu, Abhik; Joanny, Jean-Francois; Prost, Jacques; Jülicher, Frank

    2012-01-01

    Inspired by recent experiments in cell biology, we elucidate the visco-elastic properties of an active gel by studying the dynamics of a small tracer particle inside it. In a stochastic hydrodynamic approach for an active gel of finite thickness L, we calculate the mean square displacement of a particle. These particle displacements are governed by fluctuations in the velocity field. We characterize the short-time behavior when the gel is a solid as well as the limit of long times when the gel becomes a fluid and the particle shows simple diffusion. Active stresses together with local polar order give rise to velocity fluctuations that lead to characteristic behaviors of the diffusion coefficient that differ fundamentally from those found in a passive system: the diffusion coefficient can depend on system size and diverges as L approaches an instability threshold. Furthermore, the diffusion coefficient becomes independent of the particle size in this case. (paper)

  2. Diffusion coefficients for unattached decay products of thoron - dependence on ventilation and relative humidity

    International Nuclear Information System (INIS)

    Kotrappa, P.; Bhanti, D.P.; Raghunath, B.

    1976-01-01

    The results of a study of the diffusivity of unattached decay products of thoron with respect to air changes using a recently developed diffusion sampler are reported. The dependence of diffusivity of radon/thoron decay products on relative humidity has also been investigated by measurement of diffusion coefficients in an atmosphere where relative humidities varied from 5 to 90%. Results are shown tabulated. (U.K.)

  3. Apparent diffusion coefficient and vascular signal fraction measurements with magnetic resonance imaging: feasibility in metastatic ovarian cancer at 3 Tesla. Technical development

    International Nuclear Information System (INIS)

    Sala, Evis; Priest, Andrew N.; Kataoka, Masako; Graves, Martin J.; Joubert, Ilse; Lomas, David J.; McLean, Mary A.; Griffiths, John R.; Crawford, Robin A.F.; Jimenez-Linan, Mercedes; Earl, Helena M.; Brenton, James D.

    2010-01-01

    This prospective study aims to evaluate the feasibility of DWI at 3 Tesla in patients with advanced ovarian cancer and investigate the differences in vascular signal fraction (VSF) and apparent diffusion coefficient (ADC) values between primary ovarian mass and metastatic disease. Twenty patients with suspected advanced ovarian carcinoma were enrolled in the study. High-resolution T2W FRFSE images were used to confirm the position of three marker lesions: primary ovarian mass, omental cake and peritoneal deposit. Multislice DWI was acquired in a single breath-hold using multiple b-values. The three marker lesions were outlined by an experienced radiologist on ADC and VSF maps. Ovarian lesions showed the highest ADC values. The mean ADC value for peritoneal deposits was significantly lower than for both ovarian lesions (p = 0.03) and omental cake (p = 0.03). The VSF for omental cake was significantly higher than for ovarian lesions (p = 0.01) and peritoneal deposits (p = 0.04). There was a significant positive correlation between ADC and VSF for peritoneal deposits (p = 0.04). DWI in advanced ovarian cancer is feasible at 3 T. There are significant differences in baseline ADC and VSF values between ovarian cancer, omental cake and peritoneal deposits that may explain the mixed treatment response that occurs at different disease sites. (orig.)

  4. The mutual diffusion coefficient for (meth)acrylate monomers as determined with a nuclear microprobe

    International Nuclear Information System (INIS)

    Leewis, Christian M.; Mutsaers, Peter H.A.; Jong, Arthur M. de; Ijzendoorn, Leo J. van; Voigt, Martien J.A. de; Ren, Min Q.; Watt, Frank; Broer, Dirk J.

    2004-01-01

    The value of the mutual diffusion coefficient D V of two acrylic monomers is determined with nuclear microprobe measurements on a set of polymer films. These films have been prepared by allowing the monomers to diffuse into each other for a certain time and subsequently applying fast ultraviolet photo-polymerization, which freezes the concentration profile. The monomer diffusion profiles are studied with a scanning 2.1 MeV proton microprobe. Each monomer contains a marker element, e.g., Cl and Si, which are easily detected with proton induced x-ray emission. From the diffusion profiles, it is possible to determine the mutual diffusion coefficient. The mutual diffusion coefficient is dependent of concentration, which is concluded from the asymmetry in the Cl- and Si-profiles. A linear dependence of the mutual diffusion coefficient on the composition is used as a first order approximation. The best fits are obtained for a value of b=(0.38±0.15), which is the ratio of the diffusion coefficient of 1,3-bis(3-methacryloxypropyl)-1, 1,3,3-tetramethyldisiloxane in pure 2-chloroethyl acrylate and the diffusion coefficient of 2-chloroethyl acrylate in pure 1,3-bis(3-methacryloxypropyl)-1,1,3,3-tetramethyldisiloxane. Under the assumption of a linear dependence of the mutual diffusion coefficient D V on monomer composition, it follows that D V =(2.9±0.6)·10 -10 m 2 /s at a 1:1 monomer ratio. With Flory-Huggins expressions for the monomer chemical potentials, one can derive approximate values for the individual monomer diffusion coefficients

  5. THE DETERMINATION OF DIFFUSION COEFFICIENT OF INVERT MATERIALS

    International Nuclear Information System (INIS)

    P. Heller and J. Wright

    2000-01-01

    The Engineered Barrier System (EBS) Testing Department is performing tests in the Department of Energy's Atlas Facility to evaluate the performance of various means for increasing the time for breakthrough of radionuclides from the waste package to the base of the invert. This includes testing various barriers in the invert as a means of increasing breakthrough time through the process of diffusion. A diffusion barrier may serve as an invert material for the emplacement drifts. The invert material may consist of crushed tuff from the repository excavation at Yucca Mountain or silica sand. The objective of this report is to determine the diffusion coefficient of the crushed tuff and silica sand invert materials specified by the EBS Testing Department. The laboratory derived information from the testing was used in the Nernst-Einstein equation (Jurinak et al. 1987, p. 626) to determine the diffusion coefficient of the invert material. This report transmits the results and describes the methodology and interpretation. The scope of this report is to determine the diffusion coefficients of the invert materials mentioned above using the centrifuge at UFA Ventures. Standard laboratory procedures, described in Section 2 of this report, were used. The diffusion coefficients are to be determined over a range of moisture contents. The report contains the diffusion coefficients calculated by the Nernst-Einstein equation (Jurinak et al. 1987, p. 626) that become a part of the Technical Database. Raw data is also included in the report, however this data does not become part of the Technical Database as per Section 3.23 of AP-SIII.3Q ''Submittal and Incorporation of Data to the Technical Data Management System''. A sieve analysis of the samples was not conducted as part of this report, but sieve analysis may be accomplished as part of other reports. Two samples of crushed tuff and two samples of silica sand were tested

  6. Scale dependence of the effective matrix diffusion coefficient: Evidence and preliminary interpretation

    International Nuclear Information System (INIS)

    Liu, Hui-Hai; Zhang, Yingqi; Molz, Fred J.

    2006-01-01

    The exchange of solute mass (through molecular diffusion) between fluid in fractures and fluid in the rock matrix is called matrix diffusion. Owing to the orders-of-magnitude slower flow velocity in the matrix compared to fractures, matrix diffusion can significantly retard solute transport in fractured rock, and therefore is an important process for a variety of problems, including remediation of subsurface contamination and geological disposal of nuclear waste. The effective matrix diffusion coefficient (molecular diffusion coefficient in free water multiplied by matrix tortuosity) is an important parameter for describing matrix diffusion, and in many cases largely determines overall solute transport behavior. While matrix diffusion coefficient values measured from small rock samples in the laboratory are generally used for modeling field-scale solute transport in fractured rock (Boving and Grathwohl, 2001), several research groups recently have independently found that effective matrix diffusion coefficients much larger than laboratory measurements are needed to match field-scale tracer-test data (Neretnieks, 2002; Becker and Shapiro, 2000; Shapiro, 2001; Liu et al., 2003, 2004a). In addition to the observed enhancement, Liu et al. (2004b), based on a relatively small number of field-test results, reported that the effective matrix diffusion coefficient might be scale dependent, and, like permeability and dispersivity, it seems to increases with test scale. This scale-dependence has important implications for large-scale solute transport in fractured rock. Although a number of mechanisms have been proposed to explain the enhancement of the effective matrix diffusion coefficient, the potential scale dependence and its mechanisms are not fully investigated at this stage. The major objective of this study is to again demonstrate (based on more data published in the literature than those used in Liu et al. [2004b]) the potential scale dependence of the effective

  7. Scale Dependence of the Effective Matrix Diffusion Coefficient : Evidence and Preliminary Interpretation

    International Nuclear Information System (INIS)

    H.H. Liu; Y. Zhang

    2006-01-01

    The exchange of solute mass (through molecular diffusion) between fluid in fractures and fluid in the rock matrix is called matrix diffusion. Owing to the orders-of-magnitude slower flow velocity in the matrix compared to fractures, matrix diffusion can significantly retard solute transport in fractured rock, and therefore is an important process for a variety of problems, including remediation of subsurface contamination and geological disposal of nuclear waste. The effective matrix diffusion coefficient (molecular diffusion coefficient in free water multiplied by matrix tortuosity) is an important parameter for describing matrix diffusion, and in many cases largely determines overall solute transport behavior. While matrix diffusion coefficient values measured from small rock samples in the laboratory are generally used for modeling field-scale solute transport in fractured rock (Boving and Grathwohl, 2001), several research groups recently have independently found that effective matrix diffusion coefficients much larger than laboratory measurements are needed to match field-scale tracer-test data (Neretnieks, 2002; Becker and Shapiro, 2000; Shapiro, 2001; Liu et al., 2003,2004a). In addition to the observed enhancement, Liu et al. (2004b), based on a relatively small number of field-test results, reported that the effective matrix diffusion coefficient might be scale dependent, and, like permeability and dispersivity, it seems to increases with test scale. This scale-dependence has important implications for large-scale solute transport in fractured rock. Although a number of mechanisms have been proposed to explain the enhancement of the effective matrix diffusion coefficient, the potential scale dependence and its mechanisms are not fully investigated at this stage. The major objective of this study is to again demonstrate (based on more data published in the literature than those used in Liu et al. [2004b]) the potential scale dependence of the effective

  8. Flux-limited diffusion coefficients in reactor physics applications

    International Nuclear Information System (INIS)

    Pounders, J.; Rahnema, F.; Szilard, R.

    2007-01-01

    Flux-limited diffusion theory has been successfully applied to problems in radiative transfer and radiation hydrodynamics, but its relevance to reactor physics has not yet been explored. The current investigation compares the performance of a flux-limited diffusion coefficient against the traditionally defined transport cross section. A one-dimensional BWR benchmark problem is examined at both the assembly and full-core level with varying degrees of heterogeneity. (authors)

  9. Determination of diffusion coefficients of various livestock antibiotics in water at infinite dilution

    Directory of Open Access Journals (Sweden)

    Soriano Allan N.

    2017-01-01

    Full Text Available The fate of antibiotics entering the environment raised concerns on the possible effect of antimicrobial resistance bacteria. Prediction of the fate and transport of these particles are needed to be determined, significantly the diffusion coefficient of antibiotic in water at infinite dilution. A systematic determination of diffusion coefficient of antibiotic in water at infinite dilution of five different kinds of livestock antibiotics namely: Amtyl, Ciprotyl, Doxylak Forte, Trisullak, and Vetracin Gold in the 293.15 to 313.15 K temperature range are reported through the use of the method involving the electrolytic conductivity measurements. A continuous stirred tank reactor is utilized to measure the electrolytic conductivities of the considered systems. These conductivities are correlated by using the Nernst-Haskell equation to determine the infinite dilution diffusion coefficient. Determined diffusion coefficients are based on the assumption that in dilute solution, these antibiotics behave as strong electrolyte from which H+ cation dissociate from the antibiotic’s anion.

  10. Determination of diffusion coefficients of various livestock antibiotics in water at infinite dilution

    Science.gov (United States)

    Soriano, Allan N.; Adamos, Kristoni G.; Bonifacio, Pauline B.; Adornado, Adonis P.; Bungay, Vergel C.; Vairavan, Rajendaran

    2017-11-01

    The fate of antibiotics entering the environment raised concerns on the possible effect of antimicrobial resistance bacteria. Prediction of the fate and transport of these particles are needed to be determined, significantly the diffusion coefficient of antibiotic in water at infinite dilution. A systematic determination of diffusion coefficient of antibiotic in water at infinite dilution of five different kinds of livestock antibiotics namely: Amtyl, Ciprotyl, Doxylak Forte, Trisullak, and Vetracin Gold in the 293.15 to 313.15 K temperature range are reported through the use of the method involving the electrolytic conductivity measurements. A continuous stirred tank reactor is utilized to measure the electrolytic conductivities of the considered systems. These conductivities are correlated by using the Nernst-Haskell equation to determine the infinite dilution diffusion coefficient. Determined diffusion coefficients are based on the assumption that in dilute solution, these antibiotics behave as strong electrolyte from which H+ cation dissociate from the antibiotic's anion.

  11. Maxwell-Stefan diffusion coefficient estimation for ternary systems: an ideal ternary alcohol system.

    Science.gov (United States)

    Allie-Ebrahim, Tariq; Zhu, Qingyu; Bräuer, Pierre; Moggridge, Geoff D; D'Agostino, Carmine

    2017-06-21

    The Maxwell-Stefan model is a popular diffusion model originally developed to model diffusion of gases, which can be considered thermodynamically ideal mixtures, although its application has been extended to model diffusion in non-ideal liquid mixtures as well. A drawback of the model is that it requires the Maxwell-Stefan diffusion coefficients, which are not based on measurable quantities but they have to be estimated. As a result, numerous estimation methods, such as the Darken model, have been proposed to estimate these diffusion coefficients. However, the Darken model was derived, and is only well defined, for binary systems. This model has been extended to ternary systems according to two proposed forms, one by R. Krishna and J. M. van Baten, Ind. Eng. Chem. Res., 2005, 44, 6939-6947 and the other by X. Liu, T. J. H. Vlugt and A. Bardow, Ind. Eng. Chem. Res., 2011, 50, 10350-10358. In this paper, the two forms have been analysed against the ideal ternary system of methanol/butan-1-ol/propan-1-ol and using experimental values of self-diffusion coefficients. In particular, using pulsed gradient stimulated echo nuclear magnetic resonance (PGSTE-NMR) we have measured the self-diffusion coefficients in various methanol/butan-1-ol/propan-1-ol mixtures. The experimental values of self-diffusion coefficients were then used as the input data required for the Darken model. The predictions of the two proposed multicomponent forms of this model were then compared to experimental values of mutual diffusion coefficients for the ideal alcohol ternary system. This experimental-based approach showed that the Liu's model gives better predictions compared to that of Krishna and van Baten, although it was only accurate to within 26%. Nonetheless, the multicomponent Darken model in conjunction with self-diffusion measurements from PGSTE-NMR represents an attractive method for a rapid estimation of mutual diffusion in multicomponent systems, especially when compared to exhaustive

  12. Oxygen transport in waterlogged soils, Part II. Diffusion coefficients

    International Nuclear Information System (INIS)

    Obando Moncayo, F.H.

    2004-01-01

    Several equations are available for Oxygen Transport in Waterlogged Soils and have been used for soils and plants. All of them are some form of first Fick's law as given by dQ = - DA(dc/dx)/dt. This equation illustrates some important aspects of aeration in waterlogged soils; first, D is a property of the medium and the gas, and is affected by temperature T. Likewise, the amount of diffusing substance dQ in dt is a direct function of the cross sectional area A and inversely proportional to the distance x. In fact, increasing the water content of air-dry soil, drastically decreases A and creates a further resistance for the flow of oxygen through water films around root plants, soil micro organisms and soil aggregates. The solid phase is also limiting the cross-section of surface of the free gaseous diffusion and the length and tortuosity of diffusion path in soil. In most of cases, soil gas porosity and tortuosity of soil voids are expressed in the equations of diffusion as a broad 'diffusion coefficient' (apparent coefficient diffusion). The process of soil respiration is complicated, involves many parameters, and is difficult to realistically quantify. With regard to the oxygen supply, it is convenient to distinguish macro and micro models, and hence, the flux of oxygen is assumed to have two steps. The first step is related to oxygen diffusion from the atmosphere and the air-filled porosity. The second step is related to the oxygen diffusion through water-films in and around plant roots, soil micro organisms and aggregates. Because of these models we obtain coefficients of macro or micro diffusion, rates of macro or micro diffusion, etc. In the macro diffusion process oxygen is transferred in the soil profile, mainly from the soil surface to a certain depth of the root zone, while micro diffusion deals with the flux over very short distances. Both processes, macro and micro diffusion are highly influenced by soil water content. Of course, if water is added to

  13. Diffusion coefficients in 4-component mixture expressed explicitly in terms of binary diffusion coefficients and mole fractions

    International Nuclear Information System (INIS)

    Furuta, Hiroshi; Yamamoto, Ichiro

    1996-01-01

    Diffusion coefficients in 4-component mixture D ij (4) were expressed explicitly in terms of binary diffusion coefficients and mole fractions by solving a ratio of determinants defined by Hirschfelder et al. The explicit expressions of D ij (4) were divided into two terms, a term due to the i-j pairs of attention and a term common to all the pairs out of the 4 components. The two terms of D ij (4) had extended structures similar to corresponding those of D ij (3) respectively. (author)

  14. Hepatic hemangioma: Correlation of enhancement types with diffusion-weighted MR findings and apparent diffusion coefficients

    Energy Technology Data Exchange (ETDEWEB)

    Goshima, Satoshi [Department of Radiology, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan)], E-mail: gossy@par.odn.ne.jp; Kanematsu, Masayuki [Department of Radiology, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan); Department of Radiology Services, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan); Kondo, Hiroshi [Department of Radiology, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan); Yokoyama, Ryujiro; Kajita, Kimihiro [Department of Radiology Services, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan); Tsuge, Yusuke [Department of Radiology, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan); Shiratori, Yoshimune [Department of Medical Informatics, Gifu University School of Medicine, Gifu (Japan); Onozuka, Minoru [Department of Physiology and Neuroscience, Kanagawa Dental College, Yokosuka (Japan); Moriyama, Noriyuki [Research Center for Cancer Prevention and Screening, National Cancer Center Hospital, Tsukiji (Japan)

    2009-05-15

    Purpose: To correlate hepatic hemangioma enhancement types in gadolinium-enhanced magnetic resonance (MR) images with diffusion-weighted MR findings and apparent diffusion coefficients (ADCs). Materials and methods: Respiratory-triggered diffusion-weighted MR images (TR/TE, 2422/46 ms; parallel imaging factor, 2; b factor, 500 s/mm{sup 2}; number of averaging, 6) obtained in 35 patients with 44 hepatic hemangiomas diagnosed by gadolinium-enhanced MR and by follow-up imaging were retrospectively evaluated. Hemangiomas were classified into three enhancement types based on gadolinium-enhanced MR imaging findings: type I, early-enhancement type; type II, peripheral nodular enhancement type; type III, delayed enhancement type. Two blinded readers qualitatively assessed lesion sizes and signal intensities on T2-weighted turbo spin-echo and diffusion-weighted images. The ADCs of hemangiomas were also measured. Results: No significant difference was observed between the three enhancement types in terms of signal intensities on T2-weighted images. Signal intensities on diffusion-weighted images were lower in the order type I to III (P < .01), and mean ADCs were 2.18 x 10{sup -3}, 1.86 x 10{sup -3}, and 1.71 x 10{sup -3} mm{sup 2}/s for types I, II, and III, respectively (P < .01). No correlation was found between lesion sizes and ADCs. Conclusion: Hepatic hemangiomas were found to have enhancement type dependent signal intensities and ADCs on diffusion-weighted MR images. Further studies will have to substantiate that these diffusion patterns might reflect intratumoral blood flow or perfusion.

  15. Estimating the Diffusion Coefficients of Sugars Using Diffusion Experiments in Agar-Gel and Computer Simulations.

    Science.gov (United States)

    Miyamoto, Shuichi; Atsuyama, Kenji; Ekino, Keisuke; Shin, Takashi

    2018-01-01

    The isolation of useful microbes is one of the traditional approaches for the lead generation in drug discovery. As an effective technique for microbe isolation, we recently developed a multidimensional diffusion-based gradient culture system of microbes. In order to enhance the utility of the system, it is favorable to have diffusion coefficients of nutrients such as sugars in the culture medium beforehand. We have, therefore, built a simple and convenient experimental system that uses agar-gel to observe diffusion. Next, we performed computer simulations-based on random-walk concepts-of the experimental diffusion system and derived correlation formulas that relate observable diffusion data to diffusion coefficients. Finally, we applied these correlation formulas to our experimentally-determined diffusion data to estimate the diffusion coefficients of sugars. Our values for these coefficients agree reasonably well with values published in the literature. The effectiveness of our simple technique, which has elucidated the diffusion coefficients of some molecules which are rarely reported (e.g., galactose, trehalose, and glycerol) is demonstrated by the strong correspondence between the literature values and those obtained in our experiments.

  16. Determination of the chloride diffusion coefficient in blended cement mortars

    NARCIS (Netherlands)

    Elfmarkova, V.; Spiesz, P.R.; Brouwers, H.J.H.

    2015-01-01

    The rapid chloride migration test (RCM) is a commonly used accelerated test for the determination of the chloride diffusion coefficient in concrete. Nevertheless, the initial development and further experience with the RCM test concern mainly the ordinary Portland cement system. Therefore, the

  17. Redox Couples with Unequal Diffusion Coefficients: Effect on Redox Cycling

    NARCIS (Netherlands)

    Mampallil Augustine, Dileep; Mathwig, Klaus; Kang, Shuo; Lemay, Serge Joseph Guy

    2013-01-01

    Redox cycling between two electrodes separated by a narrow gap allows dramatic amplification of the faradaic current. Unlike conventional electrochemistry at a single electrode, however, the mass-transport-limited current is controlled by the diffusion coefficient of both the reduced and oxidized

  18. Plateau diffusion coefficient for arbitrary flux surface geometry

    International Nuclear Information System (INIS)

    Meier, H.K.; Hirshman, S.P.; Sigmar, D.J.; Lao, L.L.

    1981-03-01

    A relatively simple but accurate representation has been developed for magnetic flux surfaces; it is valid for finite β and it describes configurations with both ellipticity and D-shape. This representation has been applied to the computation of the diffusion coefficient in the plateau regime

  19. Pressure drop coefficient of laminar Newtonian flow in axisymmetric diffusers

    International Nuclear Information System (INIS)

    Rosa, S.; Pinho, F.T.

    2006-01-01

    The laminar flow of Newtonian fluids in axisymmetric diffusers has been numerically investigated to evaluate the pressure-loss coefficient as a function of Reynolds number, diffusion angle and expansion ratio. The numerical simulations were carried out with a finite-volume based code using non-orthogonal collocated grids and second order accurate differencing schemes to discretize all terms of the transport equations. The calculations were carried out for Reynolds numbers between 2 and 200, diffusion angles from 0 deg. to 90 deg. and expansion ratios of 1.5 and 2 and the data are presented in tabular form and as correlations. A simplified 1D theoretical analysis helped explain the various contributions to the loss coefficient and its difference relative to the reversible pressure variation due to differences between the actual and fully developed friction losses, distortions of the velocity profiles and pressure non-uniformity upstream and downstream of the expansion section

  20. Pressure drop coefficient of laminar Newtonian flow in axisymmetric diffusers

    Energy Technology Data Exchange (ETDEWEB)

    Rosa, S. [Escola Superior de Tecnologia e Gestao, Instituto Politecnico, Campus de Santa Apolonia, 5301-857 Braganca (Portugal)]. E-mail: srosa@ipb.pt; Pinho, F.T. [Centro de Estudos de Fenomenos de Transporte, DEM, Universidade do Minho, Campus de Azurem, 4800-058 Guimaraes (Portugal)]. E-mail: fpinho@fe.up.pt

    2006-04-15

    The laminar flow of Newtonian fluids in axisymmetric diffusers has been numerically investigated to evaluate the pressure-loss coefficient as a function of Reynolds number, diffusion angle and expansion ratio. The numerical simulations were carried out with a finite-volume based code using non-orthogonal collocated grids and second order accurate differencing schemes to discretize all terms of the transport equations. The calculations were carried out for Reynolds numbers between 2 and 200, diffusion angles from 0 deg. to 90 deg. and expansion ratios of 1.5 and 2 and the data are presented in tabular form and as correlations. A simplified 1D theoretical analysis helped explain the various contributions to the loss coefficient and its difference relative to the reversible pressure variation due to differences between the actual and fully developed friction losses, distortions of the velocity profiles and pressure non-uniformity upstream and downstream of the expansion section.

  1. Effective hydrogen diffusion coefficient for solidifying aluminium alloys

    International Nuclear Information System (INIS)

    Felberbaum, M.; Landry-Desy, E.; Weber, L.; Rappaz, M.

    2011-01-01

    An effective hydrogen diffusion coefficient has been calculated for two solidifying Al - 4.5 wt.% Cu and Al - 10 wt.% Cu alloys as a function of the volume fraction of solid. For this purpose, in situ X-ray tomography was performed on these alloys. For each volume fraction of solid between 0.6 and 0.9, a representative volume element of the microstructure was extracted. Solid and liquid voxels were assimilated to solid and liquid nodes in order to solve the hydrogen diffusion equation based on the chemical potential and using a finite volume formulation. An effective hydrogen diffusion coefficient based on the volume fraction of solid only could be deduced from the results of the numerical model at steady state. The results are compared with various effective medium theories.

  2. Variable Eddington factors and flux-limiting diffusion coefficients

    International Nuclear Information System (INIS)

    Whalen, P.P.

    1982-01-01

    Variable Eddington factors and flux limiting diffusion coefficients arise in two common techniques of closing the moment equations of transport. The first two moment equations of the full transport equation are still frequently used to solve many problems of radiative or particle transport. An approximate analysis, developed by Levermore, exhibits the relation between the coefficients of the two different techniques. This analysis is described and then used to test the validity of several commonly used flux limiters and Eddington factors. All of the ad-hoc flux limiters have limited validity. All of the variable Eddington factors derived from some underlying description of the angular distribution function are generally valid. The use of coefficients from Minerbo's elegant maximum entropy Eddington factor analysis is suggested for use in either flux limited diffusion or variable Eddington factor equations

  3. Determination of the zincate diffusion coefficient and its application to alkaline battery problems

    Science.gov (United States)

    May, C. E.; Kautz, H. E.

    1978-01-01

    The diffusion coefficient for the zincate ion at 24 C was found to be 9.9 x 10 to the -7th power sq cm/sec + or - 30% in 45% potassium hydroxide and 1.4 x 10 to the -7th power sq cm/sec + or - 25% in 40% sodium hydroxide. Comparison of these values with literature values at different potassium hydroxide concentrations show that the Stokes-Einstein equation is obeyed. The diffusion coefficient is characteristic of the zincate ion (not the cation) and independent of its concentration. Calculations with the measured value of the diffusion coefficient show that the zinc concentration in an alkaline zincate half-cell becomes uniform throughout in tens of hours by diffusion alone. Diffusion equations are derived which are applicable to finite-size chambers. Details and discussion of the experimental method are also given.

  4. Diffusion Decay Coefficient for Chloride Ions of Concrete Containing Mineral Admixtures

    Directory of Open Access Journals (Sweden)

    Jae-Im Park

    2016-01-01

    Full Text Available The diffusion coefficient for chloride ions and the diffusion decay coefficient for chloride ions are essential variables for a service life evaluation of concrete structures. They are influenced by water-binder ratio, exposure condition, curing temperature, cement type, and the type and use of mineral admixture. Mineral admixtures such as ground granulated blast furnace slag, fly ash, and silica fume have been increasingly used to improve resistance against chloride ions penetration in concrete structures built in an offshore environment. However, there is not enough measured data to identify the statistical properties of diffusion decay coefficient for chloride ions in concrete using mineral admixtures. This paper is aimed at evaluating the diffusion decay coefficient for chloride ions of concrete using ordinary Portland cement or blended cement. NT BUILD 492 method, an electrophoresis experiment, was used to measure the diffusion coefficient for chloride ions with ages. It was revealed from the test results that the diffusion decay coefficient for chloride ions was significantly influenced by W/B and the replacement ratio of mineral admixtures.

  5. Comparison of Experimental Methods for Estimating Matrix Diffusion Coefficients for Contaminant Transport Modeling

    Energy Technology Data Exchange (ETDEWEB)

    Telfeyan, Katherine Christina [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Ware, Stuart Douglas [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Reimus, Paul William [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Birdsell, Kay Hanson [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-11-06

    Diffusion cell and diffusion wafer experiments were conducted to compare methods for estimating matrix diffusion coefficients in rock core samples from Pahute Mesa at the Nevada Nuclear Security Site (NNSS). A diffusion wafer method, in which a solute diffuses out of a rock matrix that is pre-saturated with water containing the solute, is presented as a simpler alternative to the traditional through-diffusion (diffusion cell) method. Both methods yielded estimates of matrix diffusion coefficients that were within the range of values previously reported for NNSS volcanic rocks. The difference between the estimates of the two methods ranged from 14 to 30%, and there was no systematic high or low bias of one method relative to the other. From a transport modeling perspective, these differences are relatively minor when one considers that other variables (e.g., fracture apertures, fracture spacings) influence matrix diffusion to a greater degree and tend to have greater uncertainty than diffusion coefficients. For the same relative random errors in concentration measurements, the diffusion cell method yields diffusion coefficient estimates that have less uncertainty than the wafer method. However, the wafer method is easier and less costly to implement and yields estimates more quickly, thus allowing a greater number of samples to be analyzed for the same cost and time. Given the relatively good agreement between the methods, and the lack of any apparent bias between the methods, the diffusion wafer method appears to offer advantages over the diffusion cell method if better statistical representation of a given set of rock samples is desired.

  6. Comparison of experimental methods for estimating matrix diffusion coefficients for contaminant transport modeling

    Science.gov (United States)

    Telfeyan, Katherine; Ware, S. Doug; Reimus, Paul W.; Birdsell, Kay H.

    2018-02-01

    Diffusion cell and diffusion wafer experiments were conducted to compare methods for estimating effective matrix diffusion coefficients in rock core samples from Pahute Mesa at the Nevada Nuclear Security Site (NNSS). A diffusion wafer method, in which a solute diffuses out of a rock matrix that is pre-saturated with water containing the solute, is presented as a simpler alternative to the traditional through-diffusion (diffusion cell) method. Both methods yielded estimates of effective matrix diffusion coefficients that were within the range of values previously reported for NNSS volcanic rocks. The difference between the estimates of the two methods ranged from 14 to 30%, and there was no systematic high or low bias of one method relative to the other. From a transport modeling perspective, these differences are relatively minor when one considers that other variables (e.g., fracture apertures, fracture spacings) influence matrix diffusion to a greater degree and tend to have greater uncertainty than effective matrix diffusion coefficients. For the same relative random errors in concentration measurements, the diffusion cell method yields effective matrix diffusion coefficient estimates that have less uncertainty than the wafer method. However, the wafer method is easier and less costly to implement and yields estimates more quickly, thus allowing a greater number of samples to be analyzed for the same cost and time. Given the relatively good agreement between the methods, and the lack of any apparent bias between the methods, the diffusion wafer method appears to offer advantages over the diffusion cell method if better statistical representation of a given set of rock samples is desired.

  7. System to Measure Thermal Conductivity and Seebeck Coefficient for Thermoelectrics

    Science.gov (United States)

    Kim, Hyun-Jung; Skuza, Jonathan R.; Park, Yeonjoon; King, Glen C.; Choi, Sang H.; Nagavalli, Anita

    2012-01-01

    The Seebeck coefficient, when combined with thermal and electrical conductivity, is an essential property measurement for evaluating the potential performance of novel thermoelectric materials. However, there is some question as to which measurement technique(s) provides the most accurate determination of the Seebeck coefficient at elevated temperatures. This has led to the implementation of nonstandardized practices that have further complicated the confirmation of reported high ZT materials. The major objective of the procedure described is for the simultaneous measurement of the Seebeck coefficient and thermal diffusivity within a given temperature range. These thermoelectric measurements must be precise, accurate, and reproducible to ensure meaningful interlaboratory comparison of data. The custom-built thermal characterization system described in this NASA-TM is specifically designed to measure the inplane thermal diffusivity, and the Seebeck coefficient for materials in the ranging from 73 K through 373 K.

  8. Turbulent eddy diffusion models in exposure assessment - Determination of the eddy diffusion coefficient.

    Science.gov (United States)

    Shao, Yuan; Ramachandran, Sandhya; Arnold, Susan; Ramachandran, Gurumurthy

    2017-03-01

    The use of the turbulent eddy diffusion model and its variants in exposure assessment is limited due to the lack of knowledge regarding the isotropic eddy diffusion coefficient, D T . But some studies have suggested a possible relationship between D T and the air changes per hour (ACH) through a room. The main goal of this study was to accurately estimate D T for a range of ACH values by minimizing the difference between the concentrations measured and predicted by eddy diffusion model. We constructed an experimental chamber with a spatial concentration gradient away from the contaminant source, and conducted 27 3-hr long experiments using toluene and acetone under different air flow conditions (0.43-2.89 ACHs). An eddy diffusion model accounting for chamber boundary, general ventilation, and advection was developed. A mathematical expression for the slope based on the geometrical parameters of the ventilation system was also derived. There is a strong linear relationship between D T and ACH, providing a surrogate parameter for estimating D T in real-life settings. For the first time, a mathematical expression for the relationship between D T and ACH has been derived that also corrects for non-ideal conditions, and the calculated value of the slope between these two parameters is very close to the experimentally determined value. The values of D T obtained from the experiments are generally consistent with values reported in the literature. They are also independent of averaging time of measurements, allowing for comparison of values obtained from different measurement settings. These findings make the use of turbulent eddy diffusion models for exposure assessment in workplace/indoor environments more practical.

  9. Diffusion coefficient of hydrogen in niobium and tantalum

    International Nuclear Information System (INIS)

    Vargas, P.; Miranda, L.; Lagos, M.

    1988-08-01

    We show that the current data on hydrogen diffusion in Tantalum between 15K and 550K and in Niobium between 135K and 400K can be quantitatively explained by the small polaron theory. The experimental data can be understood assuming ground-state to ground-state tunneling between interstitial sites with tetrahedral symmetry plus an activated contribution due to tunneling between excited states having octahedral symmetry. The break of the diffusivity curve at T approx. = 250K follows naturally. It evidences the transition between the tetrahedral and octahedral hopping. For Ta the second break of the diffusivity curve at T approx. = 20K indicated the recovering of the ground-state hopping with tetrahedral symmetry. Below T approx. = 10K for Ta and T approx. = 7K for Nb the diffusion coefficient becomes independent of T. (author). 17 refs, 3 figs, 1 tab

  10. Intercomparison of diffusion coefficient derived from the through-diffusion experiment using different numerical methods

    International Nuclear Information System (INIS)

    Chih-Lung Chen; Institute of Nuclear Energy Research, Taoyuan, Taiwan; Tsing-Hai Wang; Shi-Ping Teng; Ching-Hor Lee

    2014-01-01

    Diffusion is a dominant mechanism regulating the transport of released nuclides. The through-diffusion method is typically applied to determine the diffusion coefficients (D). Depending on the design of the experiment, the concentrations in the source term [i.e., inlet reservoir (IR)] or the end term [i.e., outlet reservoir (OR)] can be fixed or vary. The combinations involve four distinct models (i.e., the CC-CC model, CC-VC model, VC-CC model, and the VC-VC model). Studies discussing the VC-CC model are scant. An analytical method considering the decay effect is required to accurately interpret the radioactive nuclide diffusion experiment results. Therefore, we developed a CC-CC model and a CC-VC model with a decay effect and the simplified formulas of these two models to determine the diffusion coefficient (i.e., the CC-CC method and CC-VC method). We also proposed two simplified methods using the VC-VC model to determine the diffusion coefficient straightforwardly based upon the concentration variation in IR and OR. More importantly, the best advantage of proposed method over others is that one can derive three diffusion coefficients based on one run of experiment. In addition, applying our CC-VC method to those data reported from Radiochemica Acta 96:111-117, 2008; and J Contam Hydrol 35:55-65, 1998, derived comparable diffusion coefficient lying in the identical order of magnitude. Furthermore, we proposed a formula to determine the conceptual critical time (Tc), which is particularly beneficial for the selection of using CC-VC or VC-VC method. Based on our proposed method, it becomes possible to calculate diffusion coefficient from a through-diffusion experiment in a shorter period of time. (author)

  11. The Gini coefficient: a methodological pilot study to assess fetal brain development employing postmortem diffusion MRI

    Energy Technology Data Exchange (ETDEWEB)

    Viehweger, Adrian; Sorge, Ina; Hirsch, Wolfgang [University Hospital Leipzig, Department of Pediatric Radiology, Leipzig (Germany); Riffert, Till; Dhital, Bibek; Knoesche, Thomas R.; Anwander, Alfred [Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig (Germany); Stepan, Holger [University Leipzig, Department of Obstetrics, Leipzig (Germany)

    2014-10-15

    Diffusion-weighted imaging (DWI) is important in the assessment of fetal brain development. However, it is clinically challenging and time-consuming to prepare neuromorphological examinations to assess real brain age and to detect abnormalities. To demonstrate that the Gini coefficient can be a simple, intuitive parameter for modelling fetal brain development. Postmortem fetal specimens(n = 28) were evaluated by diffusion-weighted imaging (DWI) on a 3-T MRI scanner using 60 directions, 0.7-mm isotropic voxels and b-values of 0, 150, 1,600 s/mm{sup 2}. Constrained spherical deconvolution (CSD) was used as the local diffusion model. Fractional anisotropy (FA), apparent diffusion coefficient (ADC) and complexity (CX) maps were generated. CX was defined as a novel diffusion metric. On the basis of those three parameters, the Gini coefficient was calculated. Study of fetal brain development in postmortem specimens was feasible using DWI. The Gini coefficient could be calculated for the combination of the three diffusion parameters. This multidimensional Gini coefficient correlated well with age (Adjusted R{sup 2} = 0.59) between the ages of 17 and 26 gestational weeks. We propose a new method that uses an economics concept, the Gini coefficient, to describe the whole brain with one simple and intuitive measure, which can be used to assess the brain's developmental state. (orig.)

  12. The Gini coefficient: a methodological pilot study to assess fetal brain development employing postmortem diffusion MRI

    International Nuclear Information System (INIS)

    Viehweger, Adrian; Sorge, Ina; Hirsch, Wolfgang; Riffert, Till; Dhital, Bibek; Knoesche, Thomas R.; Anwander, Alfred; Stepan, Holger

    2014-01-01

    Diffusion-weighted imaging (DWI) is important in the assessment of fetal brain development. However, it is clinically challenging and time-consuming to prepare neuromorphological examinations to assess real brain age and to detect abnormalities. To demonstrate that the Gini coefficient can be a simple, intuitive parameter for modelling fetal brain development. Postmortem fetal specimens(n = 28) were evaluated by diffusion-weighted imaging (DWI) on a 3-T MRI scanner using 60 directions, 0.7-mm isotropic voxels and b-values of 0, 150, 1,600 s/mm 2 . Constrained spherical deconvolution (CSD) was used as the local diffusion model. Fractional anisotropy (FA), apparent diffusion coefficient (ADC) and complexity (CX) maps were generated. CX was defined as a novel diffusion metric. On the basis of those three parameters, the Gini coefficient was calculated. Study of fetal brain development in postmortem specimens was feasible using DWI. The Gini coefficient could be calculated for the combination of the three diffusion parameters. This multidimensional Gini coefficient correlated well with age (Adjusted R 2 = 0.59) between the ages of 17 and 26 gestational weeks. We propose a new method that uses an economics concept, the Gini coefficient, to describe the whole brain with one simple and intuitive measure, which can be used to assess the brain's developmental state. (orig.)

  13. Determination of the diffusion coefficient of ionic species in Boom Clay by electromigration. First evaluation

    International Nuclear Information System (INIS)

    Maes, N.; Moors, H.; De Canniere, P.; Aertsens, M.; Put, M.

    1997-03-01

    Classical diffusion experiments for strongly retarded radionuclides take a very long time. The migration can be accelerated considerably by applying an electrical field across a saturated porous medium (electromigration). Under the influence of the electric field, the ions will attain a constant velocity which is related to the diffusion coefficient by the law of Einstein (V=zeED/KT). The displacement of the concentration profile is a direct measure for the diffusion coefficient. A description of the problems of pH-disturbances, electro-osmosis and dispersion is given and an the feasibility of the electromigration method is evaluated

  14. Diffusion simulation of ferric ions in dosemeter Fricke-gel with variable diffusion coefficient

    International Nuclear Information System (INIS)

    Milani, Caio Jacob; Bevilacqua, Joyce da Silva; Rodrigues Junior, Orlando

    2014-01-01

    Dosimetry using dosimeters Fricke-xylenol-Gel (FXG) allows confirmation and better understanding of radiotherapy treatments. The technique involves the evaluation of volumes irradiated by magnetic resonance imaging (MRI) or CT-optical. In both cases, the time spent between the irradiation and measurement is an important factor that directly influences the results. The quality of the images can be compromised by the mobility of ferric ions (Fe 3+), formed during the interaction of radiation with matter, increasing the uncertainty in determining the isodose. In this work, we simulated the dynamic involving ferric ions formed in one irradiated region irradiated in a two-dimensional domain with a variable diffusion coefficient. This phenomenon is modeled by a differential equation and solved numerically by an efficient algorithm that generalizes the Crank-Nicolson method. The stability and consistency of the method guarantee the convergence of the numerical solution for a predefined tolerance based in the choice of discretization steps of time and space. Different continuous functions were chosen to represent the diffusion coefficient and graphical views of the phenomenon are presented for a better understanding of the process

  15. Contribution to the benchmark for ternary mixtures: Measurement of diffusion and Soret coefficients of ternary system tetrahydronaphtalene-isobutylbenzene-n-dodecane with mass fractions 80-10-10 at 25 °C.

    Science.gov (United States)

    Galand, Quentin; Van Vaerenbergh, Stéfan

    2015-04-01

    This paper provides the molecular diffusion and Soret coefficients of the ternary system 1,2,3,4-tetrahydronaphtalene, isobutylbenzene, n -dodecane system at mass fractions 0.8-0.1-0.1 and temperature 25 (°)C for implementation into the benchmark presented in this topical issue. The Soret coefficients are determined by digital interferometry using the data of DSC-DCMIX microgravity experiment. The method used takes into account the influence of the thermal field on the Soret separations and the selection of the image processing techniques results in reproducible Soret coefficients.The diffusion coefficients are obtained by the Open Ended Capillary technique The fitting of the data collected through a set of two complementary experimental runs allows retrieving the four Fickian diffusion coefficients.

  16. Diffusion coefficients of gaseous scavengers in organic liquids used in radiation chemistry

    International Nuclear Information System (INIS)

    Luthjens, L.H.; De Leng, H.C.; Warman, J.M.; Hummel, A.

    1990-01-01

    Diffusion coefficients have been measured of some gaseous scavengers commonly used in radiation chemical studies: CO 2 , NH 3 , SF 6 and O 2 in trans-decalin, cyclohexane, isooctane and n-hexane, and CO 2 in cis-decalin, at 25 0 C. A modified diaphragm cell method has been used in order to limit the time needed for a measurement to about 6 h. Analysis of the results yields a simple semi-empirical predictive relation for the diffusion coefficient of a (gaseous) solute A in an organic solvent B. Diffusion coefficients calculated using the simple relation appear to give results in fair agreement with published values, over a range of organic solvents including alcohols, and over a range of temperatures. Some measured and predicted values are discussed with reference to results from the literature. (author)

  17. Eddy diffusion coefficients and their upper limits based on application of the similarity theory

    Directory of Open Access Journals (Sweden)

    M. N. Vlasov

    2015-07-01

    Full Text Available The equation for the diffusion velocity in the mesosphere and the lower thermosphere (MLT includes the terms for molecular and eddy diffusion. These terms are very similar. For the first time, we show that, by using the similarity theory, the same formula can be obtained for the eddy diffusion coefficient as the commonly used formula derived by Weinstock (1981. The latter was obtained by taking, as a basis, the integral function for diffusion derived by Taylor (1921 and the three-dimensional Kolmogorov kinetic energy spectrum. The exact identity of both formulas means that the eddy diffusion and heat transport coefficients used in the equations, both for diffusion and thermal conductivity, must meet a criterion that restricts the outer eddy scale to being much less than the scale height of the atmosphere. This requirement is the same as the requirement that the free path of molecules must be much smaller than the scale height of the atmosphere. A further result of this criterion is that the eddy diffusion coefficients Ked, inferred from measurements of energy dissipation rates, cannot exceed the maximum value of 3.2 × 106 cm2 s−1 for the maximum value of the energy dissipation rate of 2 W kg−1 measured in the mesosphere and the lower thermosphere (MLT. This means that eddy diffusion coefficients larger than the maximum value correspond to eddies with outer scales so large that it is impossible to use these coefficients in eddy diffusion and eddy heat transport equations. The application of this criterion to the different experimental data shows that some reported eddy diffusion coefficients do not meet this criterion. For example, the large values of these coefficients (1 × 107 cm2 s−1 estimated in the Turbulent Oxygen Mixing Experiment (TOMEX do not correspond to this criterion. The Ked values inferred at high latitudes by Lübken (1997 meet this criterion for summer and winter polar data, but the Ked values for summer at low latitudes

  18. Mutual diffusion coefficients of isopropanol + n-heptane and isobutanol + n-heptane

    International Nuclear Information System (INIS)

    He, Maogang; Peng, Sanguo; Zhang, Ying; Zhang, Shi; Liu, Xiangyang

    2016-01-01

    Graphical abstract: Mutual diffusion coefficients of isopropanol + n-heptane as a function of mass fraction of isopropanol. - Highlights: • D_1_2 of isopropanol + n-heptane and isobutanol + n-heptane were measured. • Effect of T, w and M of the solute on D_1_2 were analyzed. • A new correlation is proposed for the experimental data. - Abstract: The mutual diffusion coefficients of isopropanol + n-heptane and isobutanol + n-heptane were measured at different concentrations and in the temperature range from (283.15 to 323.15) K. The measurements were carried out using a digital holographic interferometry system. For all the mixtures investigated, the mutual diffusion coefficient increases as the temperature increases. At the same concentration and temperature, the mutual diffusion coefficients of isobutanol + n-heptane were lower than those of isopropanol + n-heptane due to the fact that the molecular weight of isobutanol is larger than that of isopropanol. A new correlation is proposed for the mutual diffusion coefficients of isopropanol + n-heptane and isobutanol + n-heptane. The absolute average relative deviation between the correlation and experiment is less than 1.90%.

  19. Apparatus for measurement of coefficient of friction

    Science.gov (United States)

    Slifka, A. J.; Siegwarth, J. D.; Sparks, L. L.; Chaudhuri, Dilip K.

    1990-01-01

    An apparatus designed to measure the coefficient of friction in certain controlled atmospheres is described. The coefficient of friction observed during high-load tests was nearly constant, with an average value of 0.56. This value is in general agreement with that found in the literature and also with the initial friction coefficient value of 0.67 measured during self-mated friction of 440C steel in an oxygen environment.

  20. Determination of diffusion coefficients in polypyrrole thin films using a current pulse relaxation method

    Science.gov (United States)

    Penner, Reginald M.; Vandyke, Leon S.; Martin, Charles R.

    1987-01-01

    The current pulse E sub oc relaxation method and its application to the determination of diffusion coefficients in electrochemically synthesized polypyrrole thin films is described. Diffusion coefficients for such films in Et4NBF4 and MeCN are determined for a series of submicron film thicknesses. Measurement of the double-layer capacitance, C sub dl, and the resistance, R sub u, of polypyrrole thin films as a function of potential obtained with the galvanostatic pulse method is reported. Measurements of the electrolyte concentration in reduced polypyrrole films are also presented to aid in the interpretation of the data.

  1. Radon diffusion coefficients for soils. Previous studies and their application to uranium-bearing wastes

    International Nuclear Information System (INIS)

    Sasaki, Tomozo; Gunji, Yasuyoshi; Iida, Takao

    2008-01-01

    Radon diffusion in soils has been studied over the years by many researchers. The application of such studies to the evaluation of radiation exposure caused by radon from uranium-bearing wastes disposed in a shallow land site is very important. The present paper surveyed closely relevant studies and elucidated the inherent nature of radon diffusion in terms of the definition of radon diffusion coefficients. Then, basic features of measurement methods for determining radon diffusion coefficients in soils were explained. Furthermore, theoretical aspects of radon diffusion in soils were discussed in terms of microscopic radon diffusion in soils and large-scale radon diffusion through cover soil defects for uranium mill tailings. Finally, in order to apply the radon diffusion studies to uranium-bearing waste disposal in shallow land sites, new challenges were presented: elucidation of radon diffusion in uranium-bearing wastes and cover-soil cracks, and demonstration of the validity of applying only radon diffusion in the evaluation of radiation exposure caused by radon, which would come through Japanese cover soils for uranium-bearing waste disposal. (author)

  2. Diffusion coefficients of tracers in glassy polymer systems prepared by gamma radiolysis

    International Nuclear Information System (INIS)

    Tonge, M.P.; Gilbert, R.G.

    1996-01-01

    Diffusion-controlled reactions are common in free radical polymerisation reactions, especially in glassy polymer matrices. Such reactions commonly have an important influence on the polymerisation process and final polymer properties. For example, the dominant growth-stopping event (bimolecular termination) is generally diffusion-controlled. In glassy polymer systems, where molecular mobility is very low, the chain growth mechanism (propagation) may become diffusion-controlled. At present, the mechanism for propagation in glassy polymers is poorly understood, but it is expected by the Smoluchowski expression applied to propagation to depend strongly on the diffusion coefficient of monomer. The objective of this study is to measure reliable diffusion coefficients of small tracer molecules in glassy polymers, and compare these with propagation rate coefficients in similar systems, by the prediction above. Samples were initially prepared in a sealed sampled cell containing monomer, inert diluent, and tracer dye. After irradiation for several days, complete conversion of monomer to polymer can be obtained. The diffusion coefficients for two tracer dyes have been measured as a function of weight fraction polymer glassy poly(methyl methacrylate) samples

  3. Apparent diffusion coefficient correlation with oesophageal tumour stroma and angiogenesis

    Energy Technology Data Exchange (ETDEWEB)

    Aoyagi, Tomoyoshi; Shuto, Kiyohiko; Okazumi, Shinichi; Hayano, Kohichi; Satoh, Asami; Saitoh, Hiroshige; Shimada, Hideaki; Nabeya, Yoshihiro; Matsubara, Hisahiro [Chiba University, Department of Frontier Surgery, Graduate School of Medicine, Chiba (Japan); Kazama, Toshiki [Chiba University, Department of Radiology, Graduate School of Medicine, Chiba (Japan)

    2012-06-15

    Because diffusion-weighted imaging (DWI) can predict the prognosis of patients with oesophageal squamous cell carcinoma (ESCC), we hypothesised that apparent diffusion coefficient (ADC) values might be correlated with the collagen content and tumour angiogenesis. The purpose of this study was to determine the correlation between ADC values of ESCC before treatment and oesophageal tumour stroma and angiogenesis. Seventeen patients with ESCC were enrolled. The ADC values were calculated from the DWI score. Seventeen patients who had undergone oesophagectomy were analysed for tumour stroma, vascular endothelial growth factor (VEGF) and CD34. Tissue collagen was stained with azocarmine and aniline blue to quantitatively analyse the extracellular matrix in cancer stroma. Tissues were stained with VEGF and CD34 to analyse the angiogenesis. The ADC values decreased with stromal collagen growth. We found a negative correlation between the tumour ADC and the amount of stromal collagen (r = -0.729, P = 0.001), i.e. the ADC values decreased with growth of VEGF. We also found a negative correlation between the ADC of the tumours and the amount of VEGF (r = 0.538, P = 0.026). Our results indicated that the ADC value may be a novel prognostic factor and contribute to the treatment of oesophageal cancer. circle Magnetic resonance apparent diffusion coefficient values inversely indicate tumour stromal collagen circle There is also negative correlation between ADCs and vascular endothelial growth factor circle ADC values may contribute to the treatment of oesophageal cancer. (orig.)

  4. Apparent diffusion coefficient correlation with oesophageal tumour stroma and angiogenesis

    International Nuclear Information System (INIS)

    Aoyagi, Tomoyoshi; Shuto, Kiyohiko; Okazumi, Shinichi; Hayano, Kohichi; Satoh, Asami; Saitoh, Hiroshige; Shimada, Hideaki; Nabeya, Yoshihiro; Matsubara, Hisahiro; Kazama, Toshiki

    2012-01-01

    Because diffusion-weighted imaging (DWI) can predict the prognosis of patients with oesophageal squamous cell carcinoma (ESCC), we hypothesised that apparent diffusion coefficient (ADC) values might be correlated with the collagen content and tumour angiogenesis. The purpose of this study was to determine the correlation between ADC values of ESCC before treatment and oesophageal tumour stroma and angiogenesis. Seventeen patients with ESCC were enrolled. The ADC values were calculated from the DWI score. Seventeen patients who had undergone oesophagectomy were analysed for tumour stroma, vascular endothelial growth factor (VEGF) and CD34. Tissue collagen was stained with azocarmine and aniline blue to quantitatively analyse the extracellular matrix in cancer stroma. Tissues were stained with VEGF and CD34 to analyse the angiogenesis. The ADC values decreased with stromal collagen growth. We found a negative correlation between the tumour ADC and the amount of stromal collagen (r = -0.729, P = 0.001), i.e. the ADC values decreased with growth of VEGF. We also found a negative correlation between the ADC of the tumours and the amount of VEGF (r = 0.538, P = 0.026). Our results indicated that the ADC value may be a novel prognostic factor and contribute to the treatment of oesophageal cancer. circle Magnetic resonance apparent diffusion coefficient values inversely indicate tumour stromal collagen circle There is also negative correlation between ADCs and vascular endothelial growth factor circle ADC values may contribute to the treatment of oesophageal cancer. (orig.)

  5. Correlating tumor metabolic progression index measured by serial FDG PET-CT, apparent diffusion coefficient measured by magnetic resonance imaging (MRI) and blood genomics to patient’s outcome in advanced colorectal cancer: the CORIOLAN study

    International Nuclear Information System (INIS)

    Deleporte, Amelie; Charette, Nicolas; Machiels, Godelieve; Piccart, Martine; Flamen, Patrick; Hendlisz, Alain; Paesmans, Marianne; Garcia, Camilo; Vandeputte, Caroline; Lemort, Marc; Engelholm, Jean-Luc; Hoerner, Frederic; Aftimos, Philippe; Awada, Ahmad

    2014-01-01

    Metastatic colorectal cancer (mCRC) may present various behaviours that define different courses of tumor evolution. There is presently no available tool designed to assess tumor aggressiveness, despite the fact that this is considered to have a major impact on patient outcome. CORIOLAN is a single-arm prospective interventional non-therapeutic study aiming mainly to assess the natural tumor metabolic progression index (TMPI) measured by serial FDG PET-CT without any intercurrent antitumor therapy as a prognostic factor for overall survival (OS) in patients with mCRC. Secondary objectives of the study aim to test the TMPI as a prognostic marker for progression-free survival (PFS), to assess the prognostic value of baseline tumor FDG uptake on PFS and OS, to compare TMPI to classical clinico-biological assessment of prognosis, and to test the prognostic value on OS and PFS of MRI-based apparent diffusion coefficient (ADC) and variation of vADC using voxel-based diffusion maps. Additionally, this study intends to identify genomic and epigenetic factors that correlate with progression of tumors and the OS of patients with mCRC. Consequently, this analysis will provide information about the signaling pathways that determine the natural and therapy-free course of the disease. Finally, it would be of great interest to investigate whether in a population of patients with mCRC, for which at present no known effective therapy is available, tumor aggressiveness is related to elevated levels of circulating tumor cells (CTCs) and to patient outcome. Tumor aggressiveness is one of the major determinants of patient outcome in advanced disease. Despite its importance, supported by findings reported in the literature of extreme outcomes for patients with mCRC treated with chemotherapy, no objective tool allows clinicians to base treatment decisions on this factor. The CORIOLAN study will characterize TMPI using FDG-PET-based metabolic imaging of patients with chemorefractory m

  6. Inverse method for determining radon diffusion coefficient and free radon production rate of fragmented uranium ore

    International Nuclear Information System (INIS)

    Ye, Yong-jun; Wang, Li-heng; Ding, De-xin; Zhao, Ya-li; Fan, Nan-bin

    2014-01-01

    The radon diffusion coefficient and the free radon production rate are important parameters for describing radon migration in the fragmented uranium ore. In order to determine the two parameters, the pure diffusion migration equation for radon was firstly established and its analytic solution with the two parameters to be determined was derived. Then, a self manufactured experimental column was used to simulate the pure diffusion of the radon, the improved scintillation cell method was used to measure the pore radon concentrations at different depths of the column loaded with the fragmented uranium ore, and the nonlinear least square algorithm was used to inversely determine the radon diffusion coefficient and the free radon production rate. Finally, the solution with the two inversely determined parameters was used to predict the pore radon concentrations at some depths of the column, and the predicted results were compared with the measured results. The results show that the predicted results are in good agreement with the measured results and the numerical inverse method is applicable to the determination of the radon diffusion coefficient and the free radon production rate for the fragmented uranium ore. - Highlights: • Inverse method for determining two transport parameters of radon is proposed. • A self-made experimental apparatus is used to simulate radon diffusion process. • Sampling volume and position for measuring radon concentration are optimized. • The inverse results of an experimental sample are verified

  7. Experimental techniques of conversion coefficient measurements

    International Nuclear Information System (INIS)

    Hamilton, J.H.

    1975-01-01

    Discusses briefly the history of conversion electron spectra measurements, and the interpretation of the collected data. Then provides a comprehensive review of techniques presently available to measure the conversion coefficients. (Auth.)

  8. Density dependence of the diffusion coefficient of alkali metals

    International Nuclear Information System (INIS)

    Adebayo, G.A.; Anusionwu, B.C.; Njah, A.N.; Mathew, B.; Fabamise, O.A.T.

    2004-06-01

    The effect of density on transport coefficients of liquid Li, Na and K at high temperatures using the method of Molecular Dynamics simulation has been studied. Simulation of these liquid alkali metals were carried out with 800 particles in simulation boxes with periodic boundary conditions imposed. In order to test the reliability of the interatomic potential used in the calculations, experimental data on the structural properties were compared with calculated results. The calculations showed a linear relationship between the density and the diffusion coefficient in all the systems investigated except in lithium, where, due to the small size of the atom, standard molecular dynamics simulation method may not be appropriate for calculating the properties of interest. (author)

  9. Non-destructive testing method for determining the solvent diffusion coefficient in the porous materials products

    Science.gov (United States)

    Belyaev, V. P.; Mishchenko, S. V.; Belyaev, P. S.

    2018-01-01

    Ensuring non-destructive testing of products in industry is an urgent task. Most of the modern methods for determining the diffusion coefficient in porous materials have been developed for bodies of a given configuration and size. This leads to the need for finished products destruction to make experimental samples from them. The purpose of this study is the development of a dynamic method that allows operatively determine the diffusion coefficient in finished products from porous materials without destroying them. The method is designed to investigate the solvents diffusion coefficient in building constructions from materials having a porous structure: brick, concrete and aerated concrete, gypsum, cement, gypsum or silicate solutions, gas silicate blocks, heat insulators, etc. A mathematical model of the method is constructed. The influence of the design and measuring device operating parameters on the method accuracy is studied. The application results of the developed method for structural porous products are presented.

  10. Temperature dependence of diffusion coefficients of trivalent uranium ions in chloride and chloride-fluoride melts

    International Nuclear Information System (INIS)

    Komarov, V.E.; Borodina, N.P.

    1981-01-01

    Diffusion coefficients of U 3+ ions are measured by chronopotentiometric method in chloride 3LiCl-2KCl and in mixed chloride fluoride 3LiCl(LiF)-2KCl melts in the temperature range 633-1235 K. It is shown It is shown that experimental values of diffusion-coefficients are approximated in a direct line in lg D-1/T coordinate in chloride melt in the whole temperature range and in chloride-fluoride melt in the range of 644-1040 K. Experimental values of diffusion coefficients diviate from Arrhenius equation in the direction of large values in chloride-fluoride melt at further increase of temperature up to 1235 K. Possible causes of such a diviation are considered [ru

  11. Evaluation of downwelling diffuse attenuation coefficient algorithms in the Red Sea

    KAUST Repository

    Tiwari, Surya Prakash; Yellepeddi, Sarma B.; Jones, Burton

    2016-01-01

    to comprehend the diffuse attenuation coefficient and its relationship with in situ properties. Two apparent optical properties, spectral remote sensing reflectance (Rrs) and the downwelling diffuse attenuation coefficient (Kd), are calculated from vertical

  12. A rotational diffusion coefficient of the 70s ribosome determined by depolarized laser light scattering

    NARCIS (Netherlands)

    Bruining, J.; Fijnaut, H.M.

    We have obtained a rotational diffusion coefficient of the 70S ribosome isolated from Escherichia-coli (MRE-600), from the depolarized light scattering spectrum measured by photon correlation spectroscopy. The intensity correlation function of depolarized scattered light contains contributions due

  13. Diffusion coefficients of Co, CO2, N20, and N2 in ethanol and toluene

    NARCIS (Netherlands)

    Snijder, E.D.; Snijder, E.D.; te Riele, M.J.M.; van Swaaij, Willibrordus Petrus Maria; Versteeg, Geert

    1995-01-01

    The Taylor dispersion technique was applied for the measurement of diffusion coefficients of dissolved gases in ethanol and toluene. Experiments with the system COz in H20 have been made to evaluate the accuracy of the method. The experimental procedure as described provides a fast and highly

  14. An inverse moisture diffusion algorithm for the determination of diffusion coefficient

    Science.gov (United States)

    Jen Y. Liu; William T. Simpson; Steve P. Verrill

    2000-01-01

    The finite difference approximation is applied to estimate the moisture-dependent diffusion coefficient by utilizing test data of isothermal moisture desorption in northern red oak (Quercus rubra). The test data contain moisture distributions at discrete locations across the thickness of specimens, which coincides with the radial direction of northern red oak, and at...

  15. A Quantitative Property-Property Relationship for the Internal Diffusion Coefficients of Organic Compounds in Solid Materials

    DEFF Research Database (Denmark)

    Huang, Lei; Fantke, Peter; Jolliet, Olivier

    2017-01-01

    of chemical-material combinations. This paper develops and evaluates a quantitative property-property relationship (QPPR) to predict diffusion coefficients for a wide range of organic chemicals and materials. We first compiled a training dataset of 1103 measured diffusion coefficients for 158 chemicals in 32......Indoor releases of organic chemicals encapsulated in solid materials are major contributors to human exposures and are directly related to the internal diffusion coefficient in solid materials. Existing correlations to estimate the diffusion coefficient are only valid for a limited number...... consolidated material types. Following a detailed analysis of the temperature influence, we developed a multiple linear regression model to predict diffusion coefficients as a function of chemical molecular weight (MW), temperature, and material type (adjusted R2 of 0.93). The internal validations showed...

  16. Application of numerical inverse method in calculation of composition-dependent interdiffusion coefficients in finite diffusion couples

    DEFF Research Database (Denmark)

    Liu, Yuanrong; Chen, Weimin; Zhong, Jing

    2017-01-01

    The previously developed numerical inverse method was applied to determine the composition-dependent interdiffusion coefficients in single-phase finite diffusion couples. The numerical inverse method was first validated in a fictitious binary finite diffusion couple by pre-assuming four standard...... sets of interdiffusion coefficients. After that, the numerical inverse method was then adopted in a ternary Al-Cu-Ni finite diffusion couple. Based on the measured composition profiles, the ternary interdiffusion coefficients along the entire diffusion path of the target ternary diffusion couple were...... obtained by using the numerical inverse approach. The comprehensive comparisons between the computations and the experiments indicate that the numerical inverse method is also applicable to high-throughput determination of the composition-dependent interdiffusion coefficients in finite diffusion couples....

  17. Entropy as a measure of diffusion

    International Nuclear Information System (INIS)

    Aghamohammadi, Amir; Fatollahi, Amir H.; Khorrami, Mohammad; Shariati, Ahmad

    2013-01-01

    The time variation of entropy, as an alternative to the variance, is proposed as a measure of the diffusion rate. It is shown that for linear and time-translationally invariant systems having a large-time limit for the density, at large times the entropy tends exponentially to a constant. For systems with no stationary density, at large times the entropy is logarithmic with a coefficient specifying the speed of the diffusion. As an example, the large-time behaviors of the entropy and the variance are compared for various types of fractional-derivative diffusions.

  18. Entropy as a measure of diffusion

    Energy Technology Data Exchange (ETDEWEB)

    Aghamohammadi, Amir, E-mail: mohamadi@alzahra.ac.ir; Fatollahi, Amir H., E-mail: fath@alzahra.ac.ir; Khorrami, Mohammad, E-mail: mamwad@mailaps.org; Shariati, Ahmad, E-mail: shariati@mailaps.org

    2013-10-15

    The time variation of entropy, as an alternative to the variance, is proposed as a measure of the diffusion rate. It is shown that for linear and time-translationally invariant systems having a large-time limit for the density, at large times the entropy tends exponentially to a constant. For systems with no stationary density, at large times the entropy is logarithmic with a coefficient specifying the speed of the diffusion. As an example, the large-time behaviors of the entropy and the variance are compared for various types of fractional-derivative diffusions.

  19. Correlation Between Minimum Apparent Diffusion Coefficient (ADCmin) and Tumor Cellularity: A Meta-analysis.

    Science.gov (United States)

    Surov, Alexey; Meyer, Hans Jonas; Wienke, Andreas

    2017-07-01

    Diffusion-weighted imaging (DWI) is a magnetic resonance imaging (MRI) technique based on measure of water diffusion that can provide information about tissue microstructure, especially about cell count. Increase of cell density induces restriction of water diffusion and decreases apparent diffusion coefficient (ADC). ADC can be divided into three sub-parameters: ADC minimum or ADC min , mean ADC or ADC mean and ADC maximum or ADC max Some studies have suggested that ADC min shows stronger correlations with cell count in comparison to other ADC fractions and may be used as a parameter for estimation of tumor cellularity. The aim of the present meta-analysis was to summarize correlation coefficients between ADC min and cellularity in different tumors based on large patient data. For this analysis, MEDLINE database was screened for associations between ADC and cell count in different tumors up to September 2016. For this work, only data regarding ADC min were included. Overall, 12 publications with 317 patients were identified. Spearman's correlation coefficient was used to analyze associations between ADC min and cellularity. The reported Pearson correlation coefficients in some publications were converted into Spearman correlation coefficients. The pooled correlation coefficient for all included studies was ρ=-0.59 (95% confidence interval (CI)=-0.72 to -0.45), heterogeneity Tau 2 =0.04 (pcorrelated moderately with tumor cellularity. The calculated correlation coefficient is not stronger in comparison to the reported coefficient for ADC mean and, therefore, ADC min does not represent a better means to reflect cellularity. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  20. New method and installation for rapid determination of radon diffusion coefficient in various materials

    International Nuclear Information System (INIS)

    Tsapalov, Andrey; Gulabyants, Loren; Livshits, Mihail; Kovler, Konstantin

    2014-01-01

    The mathematical apparatus and the experimental installation for the rapid determination of radon diffusion coefficient in various materials are developed. The single test lasts not longer than 18 h and allows testing numerous materials, such as gaseous and liquid media, as well as soil, concrete and radon-proof membranes, in which diffusion coefficient of radon may vary in an extremely wide range, from 1·10 −12 to 5·10 −5 m 2 /s. The uncertainty of radon diffusion coefficient estimation depends on the permeability of the sample and varies from about 5% (for the most permeable materials) to 40% (for less permeable materials, such as radon-proof membranes). - Highlights: • The new method and installation for determination of radon diffusion coefficient D are developed. • The measured D-values vary in an extremely wide range, from 5×10 -5 to 1×10 -12 m 2 /s. • The materials include water, air, soil, building materials and radon-proof membranes. • The duration of the single test does not exceed 18 hours. • The measurement uncertainty varies from 5% (in permeable materials) to 40% (in radon gas barriers)

  1. Determination of molecular diffusion coefficient in n-alkane binary mixtures: empirical correlations.

    Science.gov (United States)

    De Mezquia, D Alonso; Bou-Ali, M Mounir; Larrañaga, M; Madariaga, J A; Santamaría, C

    2012-03-08

    In this work we have measured the molecular diffusion coefficient of the n-alkane binary series nC(i)-nC(6), nC(i)-nC(10), and nC(i)-nC(12) at 298 K and 1 atm and a mass fraction of 0.5 by using the so-called sliding symmetric tubes technique. The results show that the diffusion coefficient at this concentration is proportional to the inverse viscosity of the mixture. In addition, we have also measured the diffusion coefficient of the systems nC(12)-nC(6), nC(12)-nC(7), and nC(12)-nC(8) as a function of concentration. From the data obtained, it is shown that the diffusion coefficient of the n-alkane binary mixtures at any concentration can be calculated from the molecular weight of the components and the dynamic viscosity of the corresponding mixture at 50% mass fraction.

  2. Determination of partition and diffusion coefficients of formaldehyde in selected building materials and impact of relative humidity (journal)

    Science.gov (United States)

    The partition and effective diffusion coefficients of formaldehyde were measured for three materials (conventional gypsum wallboard, "green" gypsum wallboard, and "green" carpet) under three relative humidity (RH) conditions (20%, 50% and 70% RH). A dynamic dual-chamber test meth...

  3. Determination of partition and diffusion coefficient of formaldehyde in selected building materials and impact of relative humidity

    Science.gov (United States)

    The partition and effective diffusion coefficients of formaldehyde were measured for three materials (conventional gypsum wallboard, "green" gypsum wallboard, and "green" carpet) under three relative humidity (RH) conditions (20%, 50% and 70% RH). A dynamic dual-chamber test meth...

  4. Torsion method for measuring piezooptic coefficients

    Energy Technology Data Exchange (ETDEWEB)

    Skab, I.; Smaga, I.; Savaryn, V.; Vasylkiv, Yu.; Vlokh, R. [Institute of Physical Optics, Lviv (Ukraine)

    2011-01-15

    We develop and describe analytically a torsion method for measuring piezooptic coefficients associated with shear stresses. It is shown that the method enables to increase significantly the accuracy of determination of piezooptic coefficients. The method and the appropriate apparatus are verified experimentally on the example of LiNbO{sub 3} crystals. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  5. Evaporation Kinetics of Polyol Droplets: Determination of Evaporation Coefficients and Diffusion Constants

    Science.gov (United States)

    Su, Yong-Yang; Marsh, Aleksandra; Haddrell, Allen E.; Li, Zhi-Ming; Reid, Jonathan P.

    2017-11-01

    In order to quantify the kinetics of mass transfer between the gas and condensed phases in aerosol, physicochemical properties of the gas and condensed phases and kinetic parameters (mass/thermal accommodation coefficients) are crucial for estimating mass fluxes over a wide size range from the free molecule to continuum regimes. In this study, we report measurements of the evaporation kinetics of droplets of 1-butanol, ethylene glycol (EG), diethylene glycol (DEG), and glycerol under well-controlled conditions (gas flow rates and temperature) using the previously developed cylindrical electrode electrodynamic balance technique. Measurements are compared with a model that captures the heat and mass transfer occurring at the evaporating droplet surface. The aim of these measurements is to clarify the discrepancy in the reported values of mass accommodation coefficient (αM, equals to evaporation coefficient based on microscopic reversibility) for 1-butanol, EG, and DEG and improve the accuracy of the value of the diffusion coefficient for glycerol in gaseous nitrogen. The uncertainties in the thermophysical and experimental parameters are carefully assessed, the literature values of the vapor pressures of these components are evaluated, and the plausible ranges of the evaporation coefficients for 1-butanol, EG, and DEG as well as uncertainty in diffusion coefficient for glycerol are reported. Results show that αM should be greater than 0.4, 0.2, and 0.4 for EG, DEG, and 1-butanol, respectively. The refined values are helpful for accurate prediction of the evaporation/condensation rates.

  6. Apparent diffusion coefficients of breast tumors. Clinical application

    International Nuclear Information System (INIS)

    Hatakenaka, Masamitsu; Soeda, Hiroyasu; Yabuuchi, Hidetake; Matsuo, Yoshio; Kamitani, Takeshi; Oda, Yoshinao; Tsuneyoshi, Masazumi; Honda, Hiroshi

    2008-01-01

    The purpose of this study was to evaluate the usefulness of apparent diffusion coefficient (ADC) for the differential diagnosis of breast tumors and to determine the relation between ADC and tumor cellularity. One hundred and thirty-six female patients (age range, 17-83 years; average age, 51.7 years) with 140 histologically proven breast tumors underwent diffusion-weighted magnetic resonance (MR) imaging (DWI) using the spin-echo echo-planar technique, and the ADCs of the tumors were calculated using 3 different b values, 0, 500, and 1000 s/mm 2 . The diagnoses consisted of fibroadenoma (FA, n=16), invasive ductal carcinoma, not otherwise specified (IDC, n=117), medullary carcinoma (ME, n=3) and mucinous carcinoma (MU, n=4). Tumor cellularity was calculated from surgical specimens. The ADCs of breast tumors and cellularity were compared between different histological types by analysis of variance and Scheffe's post hoc test. The correlation between tumor cellularity and ADC was analyzed by Pearson correlation test. Significant differences were observed in ADCs between FA and all types of cancers (P 2 =0.451). The ADC may potentially help in differentiating benign and malignant breast tumors. Tumor ADC correlates inversely with tumor cellularity. (author)

  7. Measuring methods of matrix diffusion

    International Nuclear Information System (INIS)

    Muurinen, A.; Valkiainen, M.

    1988-03-01

    In Finland the spent nuclear fuel is planned to be disposed of at large depths in crystalline bedrock. The radionuclides which are dissolved in the groundwater may be able to diffuse into the micropores of the porous rock matrix and thus be withdrawn from the flowing water in the fractures. This phenomenon is called matrix diffusion. A review over matrix diffusion is presented in the study. The main interest is directed to the diffusion of non-sorbing species. The review covers diffusion experiments and measurements of porosity, pore size, specific surface area and water permeability

  8. Solution of time dependent atmospheric diffusion equation with a proposed diffusion coefficient

    International Nuclear Information System (INIS)

    Mayhoub, A.B.; Essa, KH.S.M.; Aly, SH.

    2004-01-01

    One-dimensional model for the dispersion of passive atmospheric contaminant (not included chemical reactions) in the atmospheric boundary layer is considered. On the basis of the gradient transfer theory (K-theory), the time dependent diffusion equation represents the dispersion of the pollutants is solved analytically. The solution depends on diffusion coefficient K', which is expressed in terms of the friction velocity 'u the vertical coordinate -L and the depth of the mixing layer 'h'. The solution is obtained to either the vertical coordinate 'z' is less or greater than the mixing height 'h'. The obtained solution may be applied to study the atmospheric dispersion of pollutants

  9. Simultaneous inversion for the space-dependent diffusion coefficient and the fractional order in the time-fractional diffusion equation

    International Nuclear Information System (INIS)

    Li, Gongsheng; Zhang, Dali; Jia, Xianzheng; Yamamoto, Masahiro

    2013-01-01

    This paper deals with an inverse problem of simultaneously identifying the space-dependent diffusion coefficient and the fractional order in the 1D time-fractional diffusion equation with smooth initial functions by using boundary measurements. The uniqueness results for the inverse problem are proved on the basis of the inverse eigenvalue problem, and the Lipschitz continuity of the solution operator is established. A modified optimal perturbation algorithm with a regularization parameter chosen by a sigmoid-type function is put forward for the discretization of the minimization problem. Numerical inversions are performed for the diffusion coefficient taking on different functional forms and the additional data having random noise. Several factors which have important influences on the realization of the algorithm are discussed, including the approximate space of the diffusion coefficient, the regularization parameter and the initial iteration. The inversion solutions are good approximations to the exact solutions with stability and adaptivity demonstrating that the optimal perturbation algorithm with the sigmoid-type regularization parameter is efficient for the simultaneous inversion. (paper)

  10. Procedure for obtaining neutron diffusion coefficients from neutron transport Monte Carlo calculations (AWBA Development Program)

    International Nuclear Information System (INIS)

    Gast, R.C.

    1981-08-01

    A procedure for defining diffusion coefficients from Monte Carlo calculations that results in suitable ones for use in neutron diffusion theory calculations is not readily obtained. This study provides a survey of the methods used to define diffusion coefficients from deterministic calculations and provides a discussion as to why such traditional methods cannot be used in Monte Carlo. This study further provides the empirical procedure used for defining diffusion coefficients from the RCP01 Monte Carlo program

  11. Evaluation of downwelling diffuse attenuation coefficient algorithms in the Red Sea

    KAUST Repository

    Tiwari, Surya Prakash

    2016-05-07

    Despite the importance of the optical properties such as the downwelling diffuse attenuation coefficient for characterizing the upper water column, until recently no in situ optical measurements were published for the Red Sea. Kirby et al. used observations from the Coastal Zone Color Scanner to characterize the spatial and temporal variability of the diffuse attenuation coefficient (Kd(490)) in the Red Sea. To better understand optical variability and its utility in the Red Sea, it is imperative to comprehend the diffuse attenuation coefficient and its relationship with in situ properties. Two apparent optical properties, spectral remote sensing reflectance (Rrs) and the downwelling diffuse attenuation coefficient (Kd), are calculated from vertical profile measurements of downwelling irradiance (Ed) and upwelling radiance (Lu). Kd characterizes light penetration into water column that is important for understanding both the physical and biogeochemical environment, including water quality and the health of ocean environment. Our study tests the performance of the existing Kd(490) algorithms in the Red Sea and compares them against direct in situ measurements within various subdivisions of the Red Sea. Most standard algorithms either overestimated or underestimated with the measured in situ values of Kd. Consequently, these algorithms provided poor retrieval of Kd(490) for the Red Sea. Random errors were high for all algorithms and the correlation coefficients (r2) with in situ measurements were quite low. Hence, these algorithms may not be suitable for the Red Sea. Overall, statistical analyses of the various algorithms indicated that the existing algorithms are inadequate for the Red Sea. The present study suggests that reparameterizing existing algorithms or developing new regional algorithms is required to improve retrieval of Kd(490) for the Red Sea. © (2016) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is

  12. Diffusion measurements by Raman spectroscopy

    DEFF Research Database (Denmark)

    Hansen, Susanne Brunsgaard; Shapiro, Alexander; Berg, Rolf W.

    Poster "Diffusion measurements by Raman spectroscopy", See poster at http://www.kemi.dtu.dk/~ajo/rolf/petroday2004.ppt......Poster "Diffusion measurements by Raman spectroscopy", See poster at http://www.kemi.dtu.dk/~ajo/rolf/petroday2004.ppt...

  13. Diffusion Coefficient in the Zinc Coating Shaped on the Surface of Cast Iron and Steel Alloys

    Directory of Open Access Journals (Sweden)

    Kopyciński D.

    2015-06-01

    Full Text Available The article presents the method to assess the diffusion coefficient D in the sub-layer of intermetallic phases formed during hot-dip galvanizing “Armco” iron and ductile cast iron EN-GJS-500-7. Hot-dip galvanizing is one of the most popular forms of long-term protection of Fe-C alloys against corrosion. The process for producing a protective layer of sufficient quality is closely related to diffusion of atoms of zinc and iron. The simulation consist in performed a hot-dip galvanizing in laboratory condition above Fe-C alloys, in the Department of Engineering of Cast Alloys and Composites. Galvanizing time ranged from 15 to 300 seconds. Then metallographic specimens were prepared, intermetallic layers were measured and diffusion coefficient (D were calculated. It was found that the diffusion coefficient obtained during hot-dip galvanizing “Armco” iron and zinc is about two orders of magnitude less than the coefficient obtained on ductile cast iron EN-GJS-500-7.

  14. Diffusion of helium and estimated diffusion coefficients of hydrogen dissolved in water-saturated, compacted Ca-montmorillonite

    International Nuclear Information System (INIS)

    Higashihara, Tomohiro; Sato, Seichi; Ohashi, Hiroshi; Otsuka, Teppei

    2001-01-01

    The diffusion coefficients of hydrogen gas dissolved in water-saturated, compacted montmorillonite are required to estimate the performance of bentonite buffer materials for geological disposal of nuclear waste. As part of the effort to determine the diffusion coefficients, the diffusion coefficients of helium in water-saturated, compacted calcium montmorillonite (Ca-montmorillonite) were determined as a function of dry density, 0.78 to 1.37x10 3 kg m -3 , by a transient diffusion method. The diffusion coefficients were from 8.3x10 -10 m 2 s -1 at 0.78x10 3 kgm -3 to 2.8x10 -10 m 2 s -1 at 1.37x10 3 kgm -3 . The data obtained by this diffusion experiment of helium were highly reproducible. The diffusion coefficients of helium in Ca-montmorillonite were somewhat larger than those previously obtained for helium in sodium montmorillonite (Na-montmorillonite). The diffusion coefficients of hydrogen gas in the montmorillonites were roughly estimated using the diffusion coefficients of helium. These estimates were based on assumptions that both helium and hydrogen molecules are non-adsorptive and that the geometric factors in the compacted montmorillonites are approximately the same for diffusion of helium and diffusion of hydrogen. (author)

  15. Carpal tunnel syndrome assessment with diffusion tensor imaging. Value of fractional anisotropy and apparent diffusion coefficient

    Energy Technology Data Exchange (ETDEWEB)

    Klauser, A.S.; Kremser, C. [Medical University of Innsbruck, Department of Radiology, Innsbruck (Austria); Abd Ellah, M. [Medical University of Innsbruck, Department of Radiology, Innsbruck (Austria); Assiut University, Department of Diagnostic Radiology, South Egypt Cancer Institute, Assiut (Egypt); Taljanovic, M. [University of Arizona, College of Medicine, Banner- University Medical Center, Department of Medical Imaging, Tucson (United States); Schmidle, G.; Gabl, M. [Medical University of Innsbruck, Department for Trauma Surgery, Innsbruck (Austria); Cartes-Zumelzu, F.; Steiger, R.; Gizewski, E.R. [Medical University of Innsbruck, Department of Neuroradiology, Neuroimaging core facility, Innsbruck (Austria)

    2018-03-15

    To quantitatively assess carpal tunnel syndrome (CTS) with DTI by evaluating two approaches to determine cut-off values. In forty patients with CTS diagnosis confirmed by nerve conduction studies (NCs) and 14 healthy subjects (mean age 58.54 and 57.8 years), cross-sectional area (CSA), apparent diffusion coefficient (ADC) and fractional anisotropy (FA) at single and multiple levels with intraobserver agreement were evaluated. Maximum and mean CSA and FA showed significant differences between healthy subjects and patients (12.85 mm{sup 2} vs. 28.18 mm{sup 2}, p < 0.001, and 0.613 vs. 0.524, p=0.007, respectively) (10.12 mm{sup 2} vs. 19.9 mm{sup 2}, p<0.001 and 0.617 vs. 0.54, p=0.003, respectively), but not maximum and mean ADC (p > 0.05). For cut-off values, mean and maximum CSA showed the same sensitivity and specificity (93.3 %). However, mean FA showed better sensitivity than maximum FA (82.6 % vs. 73.9 %), but lower specificity (66.7 % vs. 80 %), and significant correlation for maximum CSA, 97 % (p < 0.01), with good correlation for maximum ADC and FA, 84.5 % (p < 0.01) and 62 % (p=0.056), respectively. CSA and FA showed significant differences between healthy subjects and patients. Single measurement at maximum CSA is suitable for FA determination. (orig.)

  16. Diffusion coefficients of radon in candidate soils for covering uranium mill tailings

    International Nuclear Information System (INIS)

    Kalkwarf, D.R.; Silker, W.B.

    1983-10-01

    Diffusion coefficients were measured for radon in 34 soils that had been identified by uranium mill personnel as candidate soils for covering their tailings piles in order to reduce radon emission. The coefficients referred to diffusion in the total pore space of the soils. They were measured by a steady-state method using soil columns compacted to greater than 80% of their Proctor maximum packing densities, but with moisture contents generally less than would be expected at a tailings site. Three published empirical equations relating diffusion coefficients to soil moisture and porosity were tested with these data. The best fir was obtained with the equation: D = 0.70 exp [-4(m-mP 2 +m 5 )] in which P is the dry porosity of the soil and m is its moisture saturation, i.e. the fraction of pore volume filled with water. This equation was used to extrapolate measured coefficients to values expected at soil-moisture contents representative of tailings sites in the western United States. Extrapolated values for silty sands and clayey sands range from 0.004 to 0.06 cm 2 /s where w, the weight ratio of water to dry soil, is expected to vary from 0.04 to 0.09. Values for inorganic silts and clays ranged from 0.001 to 0.02 cm 2 /s where w is expected to vary from 0.10 to 0.13. 8 references, 1 figure, 1 table

  17. Comparison of diffusion coefficients and activation energies for AG diffusion in silicon carbide

    International Nuclear Information System (INIS)

    Kim, Bong Goo; Yeo, Sung Hwan; Lee, Young Woo; Cho, Moon Sung

    2015-01-01

    The migration of silver (Ag) in silicon carbide (SiC) and 110mAg through SiC of irradiated tri-structural isotropic (TRISO) fuel has been studied for the past three to four decades. However, there is no satisfactory explanation for the transport mechanism of Ag in SiC. In this work, the diffusion coefficients of Ag measured and/or estimated in previous studies were reviewed, and then pre-exponential factors and activation energies from the previous experiments were evaluated using Arrhenius equation. The activation energy is 247.4 kJ·mol -1 from Ag paste experiments between two SiC layers produced using fluidized-bed chemical vapor deposition (FBCVD), 125.3 kJ·mol -1 from integral release experiments (annealing of irradiated TRISO fuel), 121.8 kJ·mol -1 from fractional Ag release during irradiation of TRISO fuel in high flux reactor (HFR), and 274.8 kJ·mol -1 from Ag ion implantation experiments, respectively. The activation energy from ion implantation experiments is greater than that from Ag paste, fractional release and integral release, and the activation energy from Ag paste experiments is approximately two times greater than that from integral release experiments and fractional Ag release during the irradiation of TRISO fuel in HFR. The pre-exponential factors are also very different depending on the experimental methods and estimation. From a comparison of the pre-exponential factors and activation energies, it can be analogized that the diffusion mechanism of Ag using ion implantation experiment is different from other experiments, such as a Ag paste experiment, integral release experiments, and heating experiments after irradiating TRISO fuel in HFR. However, the results of this work do not support the long held assumption that Ag release from FBCVD-SiC, used for the coating layer in TRISO fuel, is dominated by grain boundary diffusion. In order to understand in detail the transport mechanism of Ag through the coating layer, FBCVD-SiC in TRISO fuel, a

  18. Measuring Resource Inequality: The Gini Coefficient

    Directory of Open Access Journals (Sweden)

    Michael T. Catalano

    2009-07-01

    Full Text Available This paper stems from work done by the authors at the Mathematics for Social Justice Workshop held in June of 2007 at Middlebury College. We provide a description of the Gini coefficient and some discussion of how it can be used to promote quantitative literacy skills in mathematics courses. The Gini Coefficient was introduced in 1921 by Italian statistician Corrado Gini as a measure of inequality. It is defined as twice the area between two curves. One, the Lorenz curve for a given population with respect to a given resource, represents the cumulative percentage of the resource as a function of the cumulative percentage of the population that shares that percentage of the resource. The second curve is the line y = x which is the Lorenz curve for a population which shares the resource equally. The Gini coefficient can be interpreted as the percentage of inequality represented in the population with respect to the given resource. We propose that the Gini coefficient can be used to enhance students’ understanding of calculus concepts and provide practice for students in using both calculus and quantitative literacy skills. Our examples are based mainly on distribution of energy resources using publicly available data from the Energy Information Agency of the United States Government. For energy resources within the United States, we find that by household, the Gini coefficient is 0.346, while using the 51 data points represented by the states and Washington D.C., the Gini coefficient is 0.158. When we consider the countries of the world as a population of 210, the Gini coefficient is 0.670. We close with ideas for questions which can be posed to students and discussion of the experiences two other mathematics instructors have had incorporating the Gini coefficient into pre-calculus-level mathematics classes.

  19. Friction Coefficient Determination by Electrical Resistance Measurements

    Science.gov (United States)

    Tunyagi, A.; Kandrai, K.; Fülöp, Z.; Kapusi, Z.; Simon, A.

    2018-01-01

    A simple and low-cost, DIY-type, Arduino-driven experiment is presented for the study of friction and measurement of the friction coefficient, using a conductive rubber cord as a force sensor. It is proposed for high-school or college/university-level students. We strongly believe that it is worthwhile planning, designing and performing Arduino…

  20. A Simple Measure of Price Adjustment Coefficients.

    OpenAIRE

    Damodaran, Aswath

    1993-01-01

    One measure of market efficiency is the speed with which prices adjust to new information. The author develops a simple approach to estimating these price adjustment coefficients by using the information in return processes. This approach is used to estimate t he price adjustment coefficients for firms listed on the NYSE and the A MEX as well as for over-the-counter stocks. The author finds evidence of a lagged adjustment to new information in shorter return intervals for firms in all market ...

  1. Discrimination of paediatric brain tumours using apparent diffusion coefficient histograms

    International Nuclear Information System (INIS)

    Bull, Jonathan G.; Clark, Christopher A.; Saunders, Dawn E.

    2012-01-01

    To determine if histograms of apparent diffusion coefficients (ADC) can be used to differentiate paediatric brain tumours. Imaging of histologically confirmed tumours with pre-operative ADC maps were reviewed (54 cases, 32 male, mean age 6.1 years; range 0.1-15.8 years) comprising 6 groups. Whole tumour ADC histograms were calculated; normalised for volume. Stepwise logistic regression analysis was used to differentiate tumour types using histogram metrics, initially for all groups and then for specific subsets. All 6 groups (5 dysembryoplastic neuroectodermal tumours, 22 primitive neuroectodermal tumours (PNET), 5 ependymomas, 7 choroid plexus papillomas, 4 atypical teratoid rhabdoid tumours (ATRT) and 9 juvenile pilocytic astrocytomas (JPA)) were compared. 74% (40/54) were correctly classified using logistic regression of ADC histogram parameters. In the analysis of posterior fossa tumours, 80% of ependymomas, 100% of astrocytomas and 94% of PNET-medulloblastoma were classified correctly. All PNETs were discriminated from ATRTs (22 PNET and 4 supratentorial ATRTs) (100%). ADC histograms are useful in differentiating paediatric brain tumours, in particular, the common posterior fossa tumours of childhood. PNETs were differentiated from supratentorial ATRTs, in all cases, which has important implications in terms of clinical management. (orig.)

  2. Electron scattering on N2O-from cross sections to diffusion coefficients

    International Nuclear Information System (INIS)

    Mechlinska-Drewko, J.; Wroblewski, T.; Petrovic, Z.L.; Novakovic, V.; Karwasz, G.P.

    2003-01-01

    Results of measurements of the ratio of transverse (D T /μ) and longitudinal (D L /μ) diffusion coefficients to mobility and drift velocity (W) as function of reduced electrical field (E/N) for electrons in nitrous oxide are presented. The coefficients D T /μ and D L /μ have been determined by applying the Townsend-Huxley method. The drift velocities were obtained by using the Bradbury-Nielsen technique. Also the deduced set of total and partial cross sections has been used to calculate the D T /μ and W

  3. Nondestructive hall coefficient measurements using ACPD techniques

    Science.gov (United States)

    Velicheti, Dheeraj; Nagy, Peter B.; Hassan, Waled

    2018-04-01

    Hall coefficient measurements offer great opportunities as well as major challenges for nondestructive materials characterization. The Hall effect is produced by the magnetic Lorentz force acting on moving charge carriers in the presence of an applied magnetic field. The magnetic perturbation gives rise to a Hall current that is normal to the conduction current but does not directly perturb the electric potential distribution. Therefore, Hall coefficient measurements usually exploit the so-called transverse galvanomagnetic potential drop effect that arises when the Hall current is intercepted by the boundaries of the specimen and thereby produce a measurable potential drop. In contrast, no Hall potential is produced in a large plate in the presence of a uniform normal field at quasi-static low frequencies. In other words, conventional Hall coefficient measurements are inherently destructive since they require cutting the material under tests. This study investigated the feasibility of using alternating current potential drop (ACPD) techniques for nondestructive Hall coefficient measurements in plates. Specifically, the directional four-point square-electrode configuration is investigated with superimposed external magnetic field. Two methods are suggested to make Hall coefficient measurements in large plates without destructive machining. At low frequencies, constraining the bias magnetic field can replace constraining the dimensions of the specimen, which is inherently destructive. For example, when a cylindrical permanent magnet is used to provide the bias magnetic field, the peak Hall voltage is produced when the diameter of the magnet is equal to the diagonal of the square ACPD probe. Although this method is less effective than cutting the specimen to a finite size, the loss of sensitivity is less than one order of magnitude even at very low frequencies. In contrast, at sufficiently high inspection frequencies the magnetic field of the Hall current induces a

  4. Measuring nanoparticle diffusion in an ABELtrap

    Science.gov (United States)

    Dienerowitz, M.; Dienerowitz, F.; Börsch, M.

    2018-03-01

    Monitoring the Brownian motion of individual nanoscopic objects is key to investigate their transport properties and interactions with their close environment. Most techniques rely on transient diffusion through a detection volume or immobilisation, which restrict observation times or motility. We measure the diffusion coefficient and surface charge of individual nanoparticles and DNA molecules in an anti-Brownian electrokinetic trap (ABELtrap). This instrument is an active feedback trap confining the Brownian motion of a nanoparticle to the detection site by applying an electric field based on the particle’s current position. We simulate the Brownian motion of nanospheres in our sample geometry, including wall effects, due to partial confinement in the third dimension. The theoretically predicted values are in excellent agreement with our diffusion measurements in the ABELtrap. We also demonstrate the ABELtrap’s ability to measure varying sizes of DNA origami structures during denaturation.

  5. Diffusion coefficients-surface and interfacial tensions - Particular study of some lauryl compounds

    International Nuclear Information System (INIS)

    Morel, Jean-Emile

    1969-01-01

    Two important results of the double lipophilic and hydrophilic character of some heavy organic compounds with a polar group at the end of the chain, were studied: - In a first part, molecular diffusion coefficients were measured in order to prove the micellar aggregation of tri-laurylammonium nitrate in some organic solutions; - In a second part, the tensioactivity of some lauryl compounds (lauric acid, lauric alcohol, mono-laurylamine, etc.), was studied. (author) [fr

  6. Diffusion measurement in ferrous infused gel dosimeters

    International Nuclear Information System (INIS)

    Zahmatkesh, M. H.; Healy, B. J.

    2003-01-01

    Background: The compositions of Ferrous sulphate, Agarose and Xylenol orange dye and Ferrous sulphate, Gelatin and Xylenol orange dye in solution of distilled water and sulphuric acid are two tissue-equivalent gel dosimeters. Ionizing radiation causes oxidation of Fe 2+ ion to Fe 3+ ions which diffuse through the gel matrix and blur the image of absorbed dose over a period of hours after irradiation. Materials and methods: 25 m M sulphuric acid, 0.4 mm ferrous ammonium sulphate, 0.2 mm xylenol orange dye and 1% by weight agarose in distilled water named Agarose and Xylenol orange dye and 0.1 mm ferrous ammonium sulphate, 0.1 mm xylenol orange dye, 50 mm sulphuric acid and 5% by weight gelatin in distilled water named Gelatin and Xylenol orange dye are used as two gel dosimeters. All chemicals were supplied by Sigma Ald ridge Company, Germany. The gels were poured in Perspex casts and were irradiated to a beam of X ray from linear accelerators or X ray machine. Results: In this study diffusion coefficients of Agarose and Xylenol orange dye and Gelatin and Xylenol orange dye dosimeters have been measured through a computer program for different temperature. The ferric ion diffusion coefficient (D) for the Agarose and Xylenol orange dye and Gelatin and Xylenol orange dye dosimeters were measured as (1.19.±0.03) x 10 -2 cm 2 .hr -1 and (0.83±0.03) x 10 -2 cm 2 .hr -1 respectively at room temperature. Conclusion: For both dosimeters the diffusion coefficients decreased with gel storage temperatures down to 6 d ig C . Gelatin and Xylenol orange dye dosimeters have advantage of lower diffusion coefficient for a specified temperature

  7. Thermodiffusion, molecular diffusion and Soret coefficient of binary and ternary mixtures of n-hexane, n-dodecane and toluene.

    Science.gov (United States)

    Alonso de Mezquia, David; Wang, Zilin; Lapeira, Estela; Klein, Michael; Wiegand, Simone; Mounir Bou-Ali, M

    2014-11-01

    In this study, the thermodiffusion, molecular diffusion, and Soret coefficients of 12 binary mixtures composed of toluene, n-hexane and n-dodecane in the whole range of concentrations at atmospheric pressure and temperatures of 298.15 K and 308.15 K have been determined. The experimental measurements have been carried out using the Thermogravitational Column, the Sliding Symmetric Tubes and the Thermal Diffusion Forced Rayleigh Scattering techniques. The results obtained using the different techniques show a maximum deviation of 9% for the thermodiffusion coefficient, 8% for the molecular diffusion coefficient and 2% for the Soret coefficient. For the first time we report a decrease of the thermodiffusion coefficient with increasing ratio of the thermal expansion coefficient and viscosity for a binary mixture of an organic ring compound with a short n-alkane. This observation is discussed in terms of interactions between the different components. Additionally, the thermogravitational technique has been used to measure the thermodiffusion coefficients of four ternary mixtures consisting of toluene, n-hexane and n-dodecane at 298.15 K. In order to complete the study, the values obtained for the molecular diffusion coefficient in binary mixtures, and the thermodiffusion coefficient of binary and ternary mixtures have been compared with recently derived correlations.

  8. Evaluation of diffusion coefficients in multicomponent mixtures by means of the fluctuation theory

    DEFF Research Database (Denmark)

    Shapiro, Alexander

    2003-01-01

    We derive general expressions for diffusion coefficients in multicomponent non-ideal gas or liquid mixtures. The derivation is based on the general statistical theory of fluctuations around an equilibrium state. The matrix of diffusion coefficients is expressed in terms of the equilibrium...... characteristics. We demonstrate on several examples that the developed theory is in agreement with the established experimental facts and dependencies for the diffusion coefficients. (C) 2002 Elsevier Science B.V. All rights reserved....

  9. Effects of MR parameter changes on the quantification of diffusion anisotropy and apparent diffusion coefficient in diffusion tensor imaging: Evaluation using a diffusional anisotropic phantom

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Sang Joon; Choi, Choong Gon; Kim, Jeong Kon [Dept. of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Yun, Sung Cheol [Dept. of Biostatistics, University of Ulsan College of Medicine, Seoul (Korea, Republic of); Jeong, Ha Kyu [Dept. of Radiology, East-West Neomedical Center, Kyung Hee University College of Medicine, Seoul (Korea, Republic of); Kim, Eun Ju [Clinical Scientist, MR, Philips Healthcare, Seoul (Korea, Republic of)

    2015-04-15

    To validate the usefulness of a diffusional anisotropic capillary array phantom and to investigate the effects of diffusion tensor imaging (DTI) parameter changes on diffusion fractional anisotropy (FA) and apparent diffusion coefficient (ADC) using the phantom. Diffusion tensor imaging of a capillary array phantom was performed with imaging parameter changes, including voxel size, number of sensitivity encoding (SENSE) factor, echo time (TE), number of signal acquisitions, b-value, and number of diffusion gradient directions (NDGD), one-at-a-time in a stepwise-incremental fashion. We repeated the entire series of DTI scans thrice. The coefficients of variation (CoV) were evaluated for FA and ADC, and the correlation between each MR imaging parameter and the corresponding FA and ADC was evaluated using Spearman's correlation analysis. The capillary array phantom CoVs of FA and ADC were 7.1% and 2.4%, respectively. There were significant correlations between FA and SENSE factor, TE, b-value, and NDGD, as well as significant correlations between ADC and SENSE factor, TE, and b-value. A capillary array phantom enables repeated measurements of FA and ADC. Both FA and ADC can vary when certain parameters are changed during diffusion experiments. We suggest that the capillary array phantom can be used for quality control in longitudinal or multicenter clinical studies.

  10. Measurement of diffusive properties of intact rock

    Energy Technology Data Exchange (ETDEWEB)

    Harvey, K B

    1996-12-01

    In the Postclosure Assessment of a Reference System for the Disposal of Canada`s Nuclear Fuel Waste (Goodwin et al. 1994) the disposal vault is assumed to be surrounded by a zone of intact rock, referred to as the `exclusion zone.` A sensitivity analysis of the relative effectiveness of the several engineered and natural barriers that contribute to the safety of the reference disposal system has shown that this zone of intact rock is the most effective of these barriers to the movement of radionuclides through the reference system. Peer review of the geosphere model used in the case study for the EIS (Environmental Impact Statement) of the Canadian Nuclear Fuel Waste Management Program has identified the need to quantify the properties of the intact rock surrounding the disposal vault that would control the transport of radionuclides by diffusion. The Postclosure Assessment also identified the need for appropriate values of the free water diffusion coefficient (D{sub o}) for {sup 129}1 and {sup 14}C. The measurement of rock resistivity allows the calculation of the Formation Factor for a rock This review describes the Formation Factor, diffusivity, permeability, and porosity, and how these properties might be measured or inferred for insitu rock under the conditions that apply to the intact rock surrounding a potential disposal vault. The importance of measuring the intrinsic diffusion coefficient (D{sup i}) of diffusing species under solution salinities simulating those of groundwaters is emphasised, and a method of measurement is described that is independent of the diffusing medium, and which would be appropriate for measurements made in chemically complex media such as groundwaters. (author). 95 refs., 4 tabs., 39 figs.

  11. Measurement of diffusive properties of intact rock

    International Nuclear Information System (INIS)

    Harvey, K.B.

    1996-12-01

    In the Postclosure Assessment of a Reference System for the Disposal of Canada's Nuclear Fuel Waste (Goodwin et al. 1994) the disposal vault is assumed to be surrounded by a zone of intact rock, referred to as the 'exclusion zone.' A sensitivity analysis of the relative effectiveness of the several engineered and natural barriers that contribute to the safety of the reference disposal system has shown that this zone of intact rock is the most effective of these barriers to the movement of radionuclides through the reference system. Peer review of the geosphere model used in the case study for the EIS (Environmental Impact Statement) of the Canadian Nuclear Fuel Waste Management Program has identified the need to quantify the properties of the intact rock surrounding the disposal vault that would control the transport of radionuclides by diffusion. The Postclosure Assessment also identified the need for appropriate values of the free water diffusion coefficient (D o ) for 129 1 and 14 C. The measurement of rock resistivity allows the calculation of the Formation Factor for a rock This review describes the Formation Factor, diffusivity, permeability, and porosity, and how these properties might be measured or inferred for insitu rock under the conditions that apply to the intact rock surrounding a potential disposal vault. The importance of measuring the intrinsic diffusion coefficient (D i ) of diffusing species under solution salinities simulating those of groundwaters is emphasised, and a method of measurement is described that is independent of the diffusing medium, and which would be appropriate for measurements made in chemically complex media such as groundwaters. (author). 95 refs., 4 tabs., 39 figs

  12. On time-dependent diffusion coefficients arising from stochastic processes with memory

    Science.gov (United States)

    Carpio-Bernido, M. Victoria; Barredo, Wilson I.; Bernido, Christopher C.

    2017-08-01

    Time-dependent diffusion coefficients arise from anomalous diffusion encountered in many physical systems such as protein transport in cells. We compare these coefficients with those arising from analysis of stochastic processes with memory that go beyond fractional Brownian motion. Facilitated by the Hida white noise functional integral approach, diffusion propagators or probability density functions (pdf) are obtained and shown to be solutions of modified diffusion equations with time-dependent diffusion coefficients. This should be useful in the study of complex transport processes.

  13. Solution of the atmospheric diffusion equation with a realistic diffusion coefficient and time dependent mixing height

    International Nuclear Information System (INIS)

    Mayhoub, A.B.; Etman, S.M.

    1997-01-01

    One dimensional model for the dispersion of a passive atmospheric contaminant (neglecting chemical reactions) in the atmospheric boundary layer is introduced. The differential equation representing the dispersion of pollutants is solved on the basis of gradient-transfer theory (K- theory). The present approach deals with a more appropriate and realistic profile for the diffusion coefficient K, which is expressed in terms of the friction velocity U, the vertical coordinate z and the depth of the mixing layer h, which is taken time dependent. After some mathematical simplification, the equation analytic obtained solution can be easily applied to case study concerning atmospheric dispersion of pollutants

  14. Doppler coefficient measurements in Zebra Core 5

    International Nuclear Information System (INIS)

    Baker, A.R.; Wheeler, R.C.

    1965-11-01

    Measurements using a central hot loop in Zebra Core 5 are described. Results are given for the Doppler coefficients found in a number of assemblies with PuO 2 and 16% PuO 2 /84% depleted UO 2 pins, loaded with different combinations of steel, sodium or void pins. The mixed oxide results are in general about 20% more negative than was calculated using the FD2 data set, but agreement is good if the plutonium contributions in the calculations are omitted. The small positive Doppler coefficient calculated for Pu239 was not observed, and two measurements indicated instead a small negative effect. The Doppler effect in the mixed oxide systems was found to vary approximately as 1/T. The results from the empty loop and non-fissile assemblies indicate either a small negative Doppler effect in steel or alternatively the presence of an unexplained expansion effect. (author)

  15. Study of apparent diffusion coefficient value in the normal breastq

    International Nuclear Information System (INIS)

    Cai Shifeng

    2007-01-01

    Objective: To investigate the differences of apparent diffusion coefficient (ADC) value in normal breasts and to evaluate the correlation between ADC value and corresponding histology. Methods: Sixty-two normal breasts including 42 normal breasts of 42 patients with unilateral lesions and 20 normal breasts of 10 volunteers were studied. The ADC value of all 62 normal breasts were calculated when b value was given from 1000 to 0 s/mm 2 , 1000 to 500 s/mm 2 and 500 to 0 s/mm 2 . The MRI features of 60 normal breasts were classified into 3 types (dense, lobular-speckled, degenerative types) according to Wolf's classification and histology. Results: DWI and ADC images were different in 3 types of normal breasts because of different histologic structures. The mean ADC value of the dense type breasts was (1.70 ± 0.37) x 10 -3 mm 2 /s, the lobular-speckled type was (1.93 ± 0.46) x 10 -3 mm 2 /s and the degenerative type was (1.18 ± 0.65) x 10 -3 mm 2 /s (F=12.998, P=0.000). There were no significant differences between the dense type and the lobular-speckled type (F=2.167, P=0.147), but significant differences between the dense type and the degenerative type, the lobular-speckled type and the degenerate type (F=5.593 and 19.128; P=0.029 and 0.000). When b value decreased, the ADC value of the dense type and the lobular-speckled type increased correspondingly, but the degenerative type didn't increase apparently. Conclusion: ADC value was influenced by histologic structures in normal breasts and also was influenced by b value in the dense type and lobular-speckled type breasts. (authors)

  16. A new in-situ method to determine the apparent gas diffusion coefficient of soils

    Science.gov (United States)

    Laemmel, Thomas; Paulus, Sinikka; Schack-Kirchner, Helmer; Maier, Martin

    2015-04-01

    Soil aeration is an important factor for the biological activity in the soil and soil respiration. Generally, gas exchange between soil and atmosphere is assumed to be governed by diffusion and Fick's Law is used to describe the fluxes in the soil. The "apparent soil gas diffusion coefficient" represents the proportional factor between the flux and the gas concentration gradient in the soil and reflects the ability of the soil to "transport passively" gases through the soil. One common way to determine this coefficient is to take core samples in the field and determine it in the lab. Unfortunately this method is destructive and needs laborious field work and can only reflect a small fraction of the whole soil. As a consequence insecurity about the resulting effective diffusivity on the profile scale must remain. We developed a new in-situ method using new gas sampling device, tracer gas and inverse soil gas modelling. The gas sampling device contains several sampling depths and can be easily installed into vertical holes of an auger, which allows for fast installation of the system. At the lower end of the device inert tracer gas is injected continuously. The tracer gas diffuses into the surrounding soil. The resulting distribution of the tracer gas concentrations is used to deduce the diffusivity profile of the soil. For Finite Element Modeling of the gas sampling device/soil system the program COMSOL is used. We will present the results of a field campaign comparing the new in-situ method with lab measurements on soil cores. The new sampling pole has several interesting advantages: it can be used in-situ and over a long time; so it allows following modifications of diffusion coefficients in interaction with rain but also vegetation cycle and wind.

  17. The Effect of a Fluorophore Photo-Physics on the Lipid Vesicle Diffusion Coefficient Studied by Fluorescence Correlation Spectroscopy.

    Science.gov (United States)

    Drabik, Dominik; Przybyło, Magda; Sikorski, Aleksander; Langner, Marek

    2016-03-01

    Fluorescence Correlation Spectroscopy (FCS) is a technique, which allows determination of the diffusion coefficient and concentration of fluorescent objects suspended in the solution. The measured parameter is the fluctuation of the fluorescence signal emitted by diffusing molecules. When 100 nm DOPC vesicles labeled with various fluorescent dyes (Fluorescein-PE, NBD-PE, Atto488 DOPE or βBodipy FL) were measured, different values of diffusion coefficients have been obtained. These diffusion coefficients were different from the expected values measured using the dynamic light scattering method (DLS). The FCS was initially developed for solutions containing small fluorescent molecules therefore the observed inconsistency may result from the nature of vesicle suspension itself. The duration of the fluorescence signal may depend on the following factors: the exposure time of the labeled object to the excitation beam, the photo-physical properties (e.g., stability) of a fluorophore, the theoretical model used for the calculations of the diffusion coefficient and optical properties of the vesicle suspension. The diffusion coefficients determined for differently labeled liposomes show that its dependence on vesicle size and quantity of fluorescent probed used for labeling was significant demonstrating that the fluorescence properties of the fluorophore itself (bleaching and/or blinking) were critical factors for a correct outcome of FCS experiment. The new, based on combined FCS and DLS measurements, method for the determination of the focal volume prove itself to be useful for the evaluation of a fluorescence dye with respect to its applicability for FCS experiment.

  18. Varying coefficients model with measurement error.

    Science.gov (United States)

    Li, Liang; Greene, Tom

    2008-06-01

    We propose a semiparametric partially varying coefficient model to study the relationship between serum creatinine concentration and the glomerular filtration rate (GFR) among kidney donors and patients with chronic kidney disease. A regression model is used to relate serum creatinine to GFR and demographic factors in which coefficient of GFR is expressed as a function of age to allow its effect to be age dependent. GFR measurements obtained from the clearance of a radioactively labeled isotope are assumed to be a surrogate for the true GFR, with the relationship between measured and true GFR expressed using an additive error model. We use locally corrected score equations to estimate parameters and coefficient functions, and propose an expected generalized cross-validation (EGCV) method to select the kernel bandwidth. The performance of the proposed methods, which avoid distributional assumptions on the true GFR and residuals, is investigated by simulation. Accounting for measurement error using the proposed model reduced apparent inconsistencies in the relationship between serum creatinine and GFR among different clinical data sets derived from kidney donor and chronic kidney disease source populations.

  19. Measurement of Solute Diffusion Behavior in Fractured Waste Glass Media

    International Nuclear Information System (INIS)

    Saripalli, Kanaka P.; Lindberg, Michael J.; Meyer, Philip D.

    2008-01-01

    Determination of aqueous phase diffusion coefficients of solutes through fractured media is essential for understanding and modeling contaminants transport at many hazardous waste disposal sites. No methods for earlier measurements are available for the characterization of diffusion in fractured glass blocks. We report here the use of time-lag diffusion experimental method to assess the diffusion behavior of three different solutes (Cs, Sr and Pentafluoro Benzoic Acid or PFBA) in fractured, immobilized low activity waste (ILAW) glass forms. A fractured media time-lag diffusion experimental apparatus that allows the measurement of diffusion coefficients has been designed and built for this purpose. Use of time-lag diffusion method, a considerably easier experimental method than the other available methods, was not previously demonstrated for measuring diffusion in any fractured media. Hydraulic conductivity, porosity and diffusion coefficients of a solute were experimentally measured in fractured glass blocks using this method for the first time. Results agree with the range of properties reported for similar rock media earlier, indicating that the time-lag experimental method can effectively characterize the diffusion coefficients of fractured ILAW glass media

  20. Value of apparent diffusion coefficients in patients with brain tumors

    International Nuclear Information System (INIS)

    De Luca, Silvina; Stoisa, Daniela; Mondello, Eduardo; Vietti, Julio; Casas, Gabriel; Florenzano, Nestor; Eyheremendy, Eduardo; Martinez Boero, Macarena

    2004-01-01

    Purpose: To determine the utility of ADC values for the diagnosis of encephalic tumors. Material and method: Forty patients with encephalic tumors histopathologically confirmed, have been studied by conventional MR, diffusion and ADC maps. The intensities were measured in the solid tumor portion and the normal white matter, ratios were obtained and correlated in 13 patients with their respective cellularity indexes. Results: Seventeen were glial tumors, with lower ADC values in cases of greater malignancy. In 12 patients the diagnosis was secondary lesions in which the lowest ADC values were obtained. This feature was shared by the epidermoid cyst. The hamartomas, neurinomas, oligodendrogliomas and ependymomas have shown intermediate ADC values. Conclusion: The ADC map is a complement of conventional MR which provides additional information for the diagnosis of encephalic tumors. Low ADC values correlated with high grade malignant tumors. (author)

  1. Apparent diffusion coefficient ratio correlates significantly with prostate cancer gleason score at final pathology

    DEFF Research Database (Denmark)

    Boesen, Lars; Chabanova, Elizaveta; Løgager, Vibeke

    2015-01-01

    PURPOSE: To evaluate the correlation between apparent diffusion coefficient measurements (ADCtumor and ADCratio ) and the Gleason score from radical prostatectomy specimens. MATERIALS AND METHODS: Seventy-one patients with clinically localized prostate cancer scheduled for radical prostatectomy...... correlated with the Gleason score from the prostatectomy specimens. RESULTS: The association between ADC measurements and Gleason score showed a significant negative correlation (P ... ) and 0.90 (ADCratio ) when discriminating Gleason score ≤7(3+4) from Gleason score ≥7(4+3). CONCLUSION: ADC measurements showed a significant correlation with tumor Gleason score at final pathology. The ADCratio demonstrated the best correlation compared to the ADCtumor value and radically improved...

  2. Sorption kinetics of polycyclic aromatic hydrocarbons removal using granular activated carbon: Intraparticle diffusion coefficients

    International Nuclear Information System (INIS)

    Valderrama, C.; Gamisans, X.; Heras, X. de las; Farran, A.; Cortina, J.L.

    2008-01-01

    Granular activated carbon (GAC) was evaluated as a suitable sorbent for polycyclic aromatic hydrocarbons (PAHs) removal from aqueous solutions. For this purpose, kinetic measurements on the extraction of a family of six PAHs were taken. A morphology study was performed by means of a scanning electron microscopy (SEM) analysis of GAC samples. Analyses of the batch rate data for each PAH were carried out using two kinetic models: the homogenous particle diffusion model (HPDM) and the shell progressive model (SPM). The process was controlled by diffusion rate the solutes (PAHs) that penetrated the reacted layer at PAH concentrations in the range of 0.2-10 mg L -1 . The effective particle diffusion coefficients (D eff ) derived from the two models were determined from the batch rate data. The Weber and Morris intraparticle diffusion model made a double contribution to the surface and pore diffusivities in the sorption process. The D eff values derived from both the HPMD and SPM equations varied from 1.1 x 10 -13 to 6.0 x 10 -14 m 2 s -1 . The simplest model, the pore diffusion model, was applied first for data analysis. The model of the next level of complexity, the surface diffusion model, was applied in order to gain a deeper understanding of the diffusion process. This model is able to explain the data, and the apparent surface diffusivities are in the same order of magnitude as the values for the sorption of functionalized aromatic hydrocarbons (phenols and sulphonates) that are described in the literature

  3. Minority carrier diffusion lengths and absorption coefficients in silicon sheet material

    Science.gov (United States)

    Dumas, K. A.; Swimm, R. T.

    1980-01-01

    Most of the methods which have been developed for the measurement of the minority carrier diffusion length of silicon wafers require that the material have either a Schottky or an ohmic contact. The surface photovoltage (SPV) technique is an exception. The SPV technique could, therefore, become a valuable diagnostic tool in connection with current efforts to develop low-cost processes for the production of solar cells. The technique depends on a knowledge of the optical absorption coefficient. The considered investigation is concerned with a reevaluation of the absorption coefficient as a function of silicon processing. A comparison of absorption coefficient values showed these values to be relatively consistent from sample to sample, and independent of the sample growth method.

  4. Diffusion-weighted MR and apparent diffusion coefficient in the evaluation of severe brain injury

    International Nuclear Information System (INIS)

    Nakahara, M.; Ericson, K.; Bellander, B.M.

    2001-01-01

    Purpose: To study apparent diffusion coefficient (ADC) maps in severely brain-injured patients. Material and Methods: Four deeply comatose patients with severe brain injury were investigated with single-shot, diffusion-weighted, spin-echo echo planar imaging. The tetrahedral diffusion gradient configuration and four iterations of a set of b-values (one time of 0 mm2/s, and four times of 1000 mm2/s) were used to create isotropic ADC maps with high signal-to-noise ratio. ADC values of gray and white matter were compared among patients and 4 reference subjects. Results: one patient was diagnosed as clinically brain dead after the MR examination. The patient's ADC values of gray and white matter were significantly lower than those of 3 other brain-injured patients. In addition the ADC value of white matter was significantly lower than that of gray matter. Conclusion: The patient with fatal outcome shortly after MR examination differed significantly from other patients with severe brain injury but non-fatal outcome, with regard to ADC values in gray and white matter. This might indicate a prognostic value of ADC maps in the evaluation of traumatic brain injury

  5. Diffusion-Coefficients of Sulfate and Methane in Marine-Sediments - Influence of Porosity

    DEFF Research Database (Denmark)

    IVERSEN, N.; JØRGENSEN, BB

    1993-01-01

    diffusion coefficients can be related to the diffusion coefficient in free solution by D(s) = D(o)/theta2, where theta is the tortuosity of the sediment. The sediment tortuosity calculated from this equation showed a linear relationship with sediment porosity (phi) over the porosity range of 0.4-0.9. From...

  6. Study on the chloride diffusion coefficient in concrete obtained in electrically accelerated tests

    NARCIS (Netherlands)

    Spiesz, P.R.; Brouwers, H.J.H.; Gulikers, J.J.W.; Polder, R.; Andrade, C.

    2015-01-01

    This study presents an analysis of the chloride diffusion coefficient (DRCM), obtained in electrically accelerated chloride migration tests. As demonstrated here, the obtained chloride diffusion coefficient does not represent the apparent one, as it is independent of chloride binding. This is

  7. Correlation factor, velocity autocorrelation function and frequency-dependent tracer diffusion coefficient

    NARCIS (Netherlands)

    Beijeren, H. van; Kehr, K.W.

    1986-01-01

    The correlation factor, defined as the ratio between the tracer diffusion coefficient in lattice gases and the diffusion coefficient for a corresponding uncorrelated random walk, is known to assume a very simple form under certain conditions. A simple derivation of this is given with the aid of

  8. Temperature dependence of Self-diffusion coefficient (SDC) of liquid ...

    African Journals Online (AJOL)

    PROF HORSFALL

    2018-04-09

    Apr 9, 2018 ... inverse square relationship between the natural logarithm of self-diffusion ... using the Equilibrium Molecular Dynamics (MD) and ..... Density, and Viscosity of Liquid Aluminum and. Iron. J. Phys. Chem. Ref. Data 35 ... Atomic Diffusion in Condensed Matter. Nature. 381: 137. Einstein, A (1905). Annalen der ...

  9. Peltier coefficient measurement in a thermoelectric module

    International Nuclear Information System (INIS)

    Garrido, Javier; Casanovas, Alejandro; Chimeno, José María

    2013-01-01

    A new method for measuring the Peltier coefficient in a thermocouple X/Y based on the energy balance at the junction has been proposed recently. This technique needs only the hot and cold temperatures of a thermoelectric module when an electric current flows through it as the operational variables. The temperature evolutions of the two module sides provide an evident and accurate idea of the Peltier effect. From these temperatures, the heat transfer between the module and the ambient is also evaluated. The thermoelectric phenomena are described in the framework of an observable theory. Based on this procedure, an experiment is presented for a university teaching laboratory at the undergraduate level. (paper)

  10. Friction coefficient determination by electrical resistance measurements

    Science.gov (United States)

    Tunyagi, A.; Kandrai, K.; Fülöp, Z.; Kapusi, Z.; Simon, A.

    2018-05-01

    A simple and low-cost, DIY-type, Arduino-driven experiment is presented for the study of friction and measurement of the friction coefficient, using a conductive rubber cord as a force sensor. It is proposed for high-school or college/university-level students. We strongly believe that it is worthwhile planning, designing and performing Arduino and compatible sensor-based experiments in physics class in order to ensure a better understanding of phenomena, develop theoretical knowledge and multiple experimental skills.

  11. Temperature effects on diffusion coefficient for 6-gingerol and 6-shogaol in subcritical water extraction

    Science.gov (United States)

    Ilia Anisa, Nor; Azian, Noor; Sharizan, Mohd; Iwai, Yoshio

    2014-04-01

    6-gingerol and 6-shogaol are the main constituents as anti-inflammatory or bioactive compounds from zingiber officinale Roscoe. These bioactive compounds have been proven for inflammatory disease, antioxidatives and anticancer. The effect of temperature on diffusion coefficient for 6-gingerol and 6-shogaol were studied in subcritical water extraction. The diffusion coefficient was determined by Fick's second law. By neglecting external mass transfer and solid particle in spherical form, a linear portion of Ln (1-(Ct/Co)) versus time was plotted in determining the diffusion coefficient. 6-gingerol obtained the higher yield at 130°C with diffusion coefficient of 8.582x10-11 m2/s whilst for 6-shogaol, the higher yield and diffusion coefficient at 170°C and 19.417 × 10-11 m2/s.

  12. Temperature effects on diffusion coefficient for 6-gingerol and 6-shogaol in subcritical water extraction

    International Nuclear Information System (INIS)

    Anisa, Nor Ilia; Azian, Noor; Sharizan, Mohd; Iwai, Yoshio

    2014-01-01

    6-gingerol and 6-shogaol are the main constituents as anti-inflammatory or bioactive compounds from zingiber officinale Roscoe. These bioactive compounds have been proven for inflammatory disease, antioxidatives and anticancer. The effect of temperature on diffusion coefficient for 6-gingerol and 6-shogaol were studied in subcritical water extraction. The diffusion coefficient was determined by Fick's second law. By neglecting external mass transfer and solid particle in spherical form, a linear portion of Ln (1-(Ct/Co)) versus time was plotted in determining the diffusion coefficient. 6-gingerol obtained the higher yield at 130°C with diffusion coefficient of 8.582x10 −11 m 2 /s whilst for 6-shogaol, the higher yield and diffusion coefficient at 170°C and 19.417 × 10 −11 m 2 /s.

  13. Spin correlation parameters A{sub xx} and A{sub yy} measurements in p-p scattering from 11 to 26 MeV; Mesure des coefficients de correlation de spins A{sub xx} et A{sub yy} dans la diffusion p-p de 11 a 26 MeV

    Energy Technology Data Exchange (ETDEWEB)

    Catillon, Ph; Chapellier, M; Garreta, D [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1967-07-01

    The A{sub xx} and A{sub yy} spin correlation coefficients of the proton-proton scattering have been measured at the laboratory energies of 11,40 - 19,15 - 23,45 and 26,50 MeV for the center of mass scattering angle 90 degrees. These measurements have been made by scattering a polarized proton beam on a polarized proton target. (authors) [French] Les coefficients de correlation de spins A{sub xx} et A{sub yy} de la diffusion proton-proton ont ete mesures aux energies laboratoire de 11,40 - 19,15 - 23,45 et 26,50 MeV pour un angle de diffusion dans le centre de masse egal a 90 degres. Ces mesures ont ete effectuees par la diffusion d'un faisceau de protons polarises sur une cible de protons polarises. (auteur)

  14. Functional evaluation of hydronephrosis by diffusion-weighted MR imaging: Relationship between apparent diffusion coefficient and split glomerular filtration rate

    International Nuclear Information System (INIS)

    Toyoshima, S.; Noguchi, K.; Seto, H.; Shimizu, M.; Watanabe, N.

    2000-01-01

    To determine the relationship between apparent diffusion coefficient (ADC) values measured by diffusion-weighted MR imaging and split renal function determined by renal scintigraphy in patients with hydronephrosis. Material and Methods: Diffusion-weighted imaging on a 1.5 T MR unit and renal scintigraphy were performed in 36 patients with hydronephrosis (45 hydronephrotic kidneys, 21 non-hydronephrotic kidneys). ADC values of the individual kidneys were measured by diffusion-weighted MR imaging. Split renal function (glomerular filtration rate (GFR)) was determined by renal scintigraphy using 99m Tc-DTPA. The relationship between ADC values and split GFR was examined in 66 kidneys. The hydronephrotic kidneys were further classified into three groups (severe renal dysfunction, GFR 25 ml/min, n=28), and mean values for ADCs were calculated. Results: In hydronephrotic kidneys, there was a moderate positive correlation between ADC values and split GFR (R2=0.56). On the other hand, in non-hydronephrotic kidneys, poor correlation between ADC values and split GFR was observed (R2=0.08). The mean values for ADCs of the dysfunctioning hydronephrotic kidneys (severe renal dysfunction, 1.32x10 -3 ±0.18x10 -3 mm 2 /s; moderate renal dysfunction, 1.38x10 -3 ±0.10x10 -3 mm2/s) were significantly lower than that of the normal functioning hydronephrotic kidneys (1.63x10 -3 ±0.12±10 -3 mm 2 /s). Conclusion: These results indicated that measurement of ADC values by diffusion-weighted MR imaging has a potential value in the evaluation of the functional status of hydronephrotic kidneys

  15. Apparent Diffusion Coefficient Maps of Pediatric Mass Lesions with Free-Breathing Diffusion-Weighted Magnetic Resonance: Feasibility Study

    International Nuclear Information System (INIS)

    Olsen, Oe.E.; Sebire, N.J.

    2006-01-01

    Purpose: To assess the technical feasibility of apparent diffusion coefficient (ADC) mapping based on free-breathing diffusion-weighted magnetic resonance (DW-MR) outside the CNS in children. Material and Methods: Twelve children with mass lesions of varied histopathology were scanned with short-tau inversion recovery (STIR), contrast-enhanced T1-weighted (CE-T1W), and diffusion-weighted (b = 0, 500 and 1,000 s/mm 2 ) sequences. ADC maps were calculated. Lesion-to-background signal intensity ratios were measured and compared between STIR/CE-T1W/ADC overall (Friedman test) and between viable embryonal tumors and other lesions (Kruskal-Wallis test). Results: ADC maps clearly depicted all lesions. Lesion-to-background signal intensity ratios of STIR (median 3.7), CE-T1W (median 1.4), and ADC (median 1.6) showed no overall difference (chi-square = 3.846; P = 0.146), and there was no difference between viable embryonal tumors and other lesions within STIR/CE-T1W/ADC (chi-square 1.118/0.669/<0.001; P = 0.290/0.414/1.000, respectively). Conclusion: ADC mapping is feasible in free-breathing imaging of pediatric mass lesions outside the CNS using standard clinical equipment. Keywords: Diffusion-weighted magnetic resonance imaging; infants and children; neoplasms

  16. Determination of trapping parameters and the chemical diffusion coefficient from hydrogen permeation experiments

    International Nuclear Information System (INIS)

    Svoboda, J.; Mori, G.; Prethaler, A.; Fischer, F.D.

    2014-01-01

    Highlights: • A modeling study for diffusion of hydrogen with traps is presented. • Introduction of a new chemical diffusion coefficient. • Density of traps and average depth of traps can be determined. • Lattice diffusion and sub-surface concentration of atomic hydrogen can be determined. - Abstract: An improved diffusion theory accounting for trapping effects is applied to evaluation of hydrogen permeation experiments performed for pure iron and pearlitic and martensitic steels. The trapping parameters as molar volume and depth of traps are determined by fitting experiments by simulations based on the theory. The concentration-dependent chemical diffusion coefficient of hydrogen is extracted indicating that the trapping effect on diffusion in pure iron and pearlitic steel is negligible. However, it is significant for martensitic steel, for which the chemical diffusion coefficient cannot be considered as concentration-independent as it is established in current standards

  17. Theory of the diffusion coefficient of neutrons in a lattice containing cavities; Theorie du coefficient de diffusion des neutrons dans un reseau comportant des cavites

    Energy Technology Data Exchange (ETDEWEB)

    Benoist, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-01-15

    In an previous publication, a simple and general formulation of the diffusion coefficient, which defines the mode of weighting of the mean free paths of the various media, in introducing the collision probabilities in each medium, was established. This expression is demonstrated again here through a more direct method, and the velocity is introduced; new terms are emphasised, the existence of which implies that the representation of the diffusion area as the mean square of the straight line distance from source to absorption is not correct in a lattice. However these terms are of small enough an order of magnitude to he treated as a correction. The general expression also shows the existence, for the radial coefficient, of the series of angular correlation terms, which is seen to converge very slowly for large channels. The term by term computation which was initiated in the first work was then interrupted and a global formulation, which emphasize a resemblance with the problem of the thermal utilisation factor, was adopted. An integral method, analogous to that use for the computation of this factor, gives the possibility to establish new and simple practical formulae, which require the use of a few basic functions only. These formulae are very accurate, as seen from the results of a variational method which was studied as a reference. Various correction effects are reviewed. Expressions which allow the exact treatment of fuel rod clusters are presented. The theory is confronted with various experimental results, and a new method of measuring the radial coefficient is proposed. (author) [French] Dans une publication anterieure, on a etablie une formulation simple et generale du coefficient de diffusion, qui definit le mode de ponderation des libres parcours des differents milieux constituants en faisant apparaitre les probabilites de collision dans chaque milieu. On redemontre ici cette expression d'une maniere plus directe, tout en introduisant la variable

  18. Theory of the diffusion coefficient of neutrons in a lattice containing cavities; Theorie du coefficient de diffusion des neutrons dans un reseau comportant des cavites

    Energy Technology Data Exchange (ETDEWEB)

    Benoist, P. [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-01-15

    In an previous publication, a simple and general formulation of the diffusion coefficient, which defines the mode of weighting of the mean free paths of the various media, in introducing the collision probabilities in each medium, was established. This expression is demonstrated again here through a more direct method, and the velocity is introduced; new terms are emphasised, the existence of which implies that the representation of the diffusion area as the mean square of the straight line distance from source to absorption is not correct in a lattice. However these terms are of small enough an order of magnitude to he treated as a correction. The general expression also shows the existence, for the radial coefficient, of the series of angular correlation terms, which is seen to converge very slowly for large channels. The term by term computation which was initiated in the first work was then interrupted and a global formulation, which emphasize a resemblance with the problem of the thermal utilisation factor, was adopted. An integral method, analogous to that use for the computation of this factor, gives the possibility to establish new and simple practical formulae, which require the use of a few basic functions only. These formulae are very accurate, as seen from the results of a variational method which was studied as a reference. Various correction effects are reviewed. Expressions which allow the exact treatment of fuel rod clusters are presented. The theory is confronted with various experimental results, and a new method of measuring the radial coefficient is proposed. (author) [French] Dans une publication anterieure, on a etablie une formulation simple et generale du coefficient de diffusion, qui definit le mode de ponderation des libres parcours des differents milieux constituants en faisant apparaitre les probabilites de collision dans chaque milieu. On redemontre ici cette expression d'une maniere plus directe, tout en introduisant la variable

  19. Determination of uranium self-diffusion coefficients in the U O2 nuclear fuel by secondary ion mass spectrometry

    International Nuclear Information System (INIS)

    Ferraz, Wilmar Barbosa

    1998-01-01

    This study of uranium self-diffusion in UO 2 presents a great technological interest because its knowledge is necessary to interpret the mechanism of many important processes like, for example, sintering, creep, grain growth, in-reactor densification and others. The present work deals with new measurements of uranium diffusion in UO 2 single crystals and polycrystals through an original mythology based on the utilization of 235 U as tracer and depth profiling by secondary ions mass spectrometry (SIMS). The diffusion experiments were performed between 1498 and 1697 deg C, in H 2 atmosphere. In our experimental conditions, the uranium volume diffusion coefficients measured in UO 2 single crystals can be described by the following Arrhenius relation: D(cm 2 /s) = 8.54x10 -7 exp[-4.4(eV)/K T]. The uranium grain-boundary diffusion experiments performed in UO 2 polycrystals corresponded to the type-B diffusion. In this case, it was possible to determine the product D'δ, where D is the grain-boundary diffusion and is the width of the grain-boundary. In our experimental conditions, the product D'δ can be described by the following relation: D'δ (cm 3 /s) = 1.62x10 -5 exp[-5.6(eV)/K T]. These results that the uranium volume diffusion coefficients, measured in UO 2 single crystals, are 5 orders of magnitude lower than the uranium grain boundary diffusion coefficients measured in UO 2 polycrystalline pellets, in the same experimental conditions. This large difference between these two types of diffusivities indicates that the grain boundary is a preferential via for uranium diffusion in UO 2 polycrystalline pellet. (author)

  20. Determination of diffusion coefficients and diffusion characteristics for chlorferon and diethylthiophosphate in Ca-alginate gel beads.

    Science.gov (United States)

    Ha, Jiyeon; Engler, Cady R; Lee, Seung Jae

    2008-07-01

    Diffusion characteristics of chlorferon and diethylthiophosphate (DETP) in Ca-alginate gel beads were studied to assist in designing and operating bioreactor systems. Diffusion coefficients for chlorferon and DETP in Ca-alginate gel beads determined at conditions suitable for biodegradation studies were 2.70 x 10(-11) m(2)/s and 4.28 x 10(-11) m(2)/s, respectively. Diffusivities of chlorferon and DETP were influenced by several factors, including viscosity of the bulk solution, agitation speed, and the concentrations of diffusing substrate and immobilized cells. Diffusion coefficients increased with increasing agitation speed, probably due to poor mixing at low speed and some attrition of beads at high speeds. Diffusion coefficients also increased with decreasing substrate concentration. Increased cell concentration in the gel beads caused lower diffusivity. Theoretical models to predict diffusivities as a function of cell weight fraction overestimated the effective diffusivities for both chlorferon and DETP, but linear relations between effective diffusivity and cell weight fraction were derived from experimental data. Calcium-alginate gel beads with radii of 1.65-1.70 mm used in this study were not subject to diffusional limitations: external mass transfer resistances were negligible based on Biot number calculations and effectiveness factors indicated that internal mass transfer resistance was negligible. Therefore, the degradation rates of chlorferon and DETP inside Ca-alginate gel beads were reaction-limited. (c) 2007 Wiley Periodicals, Inc.

  1. Practical estimate of gradient nonlinearity for implementation of apparent diffusion coefficient bias correction.

    Science.gov (United States)

    Malkyarenko, Dariya I; Chenevert, Thomas L

    2014-12-01

    To describe an efficient procedure to empirically characterize gradient nonlinearity and correct for the corresponding apparent diffusion coefficient (ADC) bias on a clinical magnetic resonance imaging (MRI) scanner. Spatial nonlinearity scalars for individual gradient coils along superior and right directions were estimated via diffusion measurements of an isotropicic e-water phantom. Digital nonlinearity model from an independent scanner, described in the literature, was rescaled by system-specific scalars to approximate 3D bias correction maps. Correction efficacy was assessed by comparison to unbiased ADC values measured at isocenter. Empirically estimated nonlinearity scalars were confirmed by geometric distortion measurements of a regular grid phantom. The applied nonlinearity correction for arbitrarily oriented diffusion gradients reduced ADC bias from 20% down to 2% at clinically relevant offsets both for isotropic and anisotropic media. Identical performance was achieved using either corrected diffusion-weighted imaging (DWI) intensities or corrected b-values for each direction in brain and ice-water. Direction-average trace image correction was adequate only for isotropic medium. Empiric scalar adjustment of an independent gradient nonlinearity model adequately described DWI bias for a clinical scanner. Observed efficiency of implemented ADC bias correction quantitatively agreed with previous theoretical predictions and numerical simulations. The described procedure provides an independent benchmark for nonlinearity bias correction of clinical MRI scanners.

  2. Ischemic lesion volume determination on diffusion weighted images vs. apparent diffusion coefficient maps.

    Science.gov (United States)

    Bråtane, Bernt Tore; Bastan, Birgul; Fisher, Marc; Bouley, James; Henninger, Nils

    2009-07-07

    Though diffusion weighted imaging (DWI) is frequently used for identifying the ischemic lesion in focal cerebral ischemia, the understanding of spatiotemporal evolution patterns observed with different analysis methods remains imprecise. DWI and calculated apparent diffusion coefficient (ADC) maps were serially obtained in rat stroke models (MCAO): permanent, 90 min, and 180 min temporary MCAO. Lesion volumes were analyzed in a blinded and randomized manner by 2 investigators using (i) a previously validated ADC threshold, (ii) visual determination of hypointense regions on ADC maps, and (iii) visual determination of hyperintense regions on DWI. Lesion volumes were correlated with 24 hour 2,3,5-triphenyltetrazoliumchloride (TTC)-derived infarct volumes. TTC-derived infarct volumes were not significantly different from the ADC and DWI-derived lesion volumes at the last imaging time points except for significantly smaller DWI lesions in the pMCAO model (p=0.02). Volumetric calculation based on TTC-derived infarct also correlated significantly stronger to volumetric calculation based on last imaging time point derived lesions on ADC maps than DWI (pdetermined lesion volumes on ADC maps and DWI by both investigators correlated significantly with threshold-derived lesion volumes on ADC maps with the former method demonstrating a stronger correlation. There was also a better interrater agreement for ADC map analysis than for DWI analysis. Ischemic lesion determination by ADC was more accurate in final infarct prediction, rater independent, and provided exclusive information on ischemic lesion reversibility.

  3. Sensitivity analysis of an experimental methodology to determine radionuclide diffusion coefficients in granite

    International Nuclear Information System (INIS)

    Alonso, U.; Missana, T.; Garcia-Gutierrez, M.; Patelli, A.; Rigato, V.

    2005-01-01

    Full text of publication follows: The long-term quantitative analysis of the migration behaviour of the relevant radionuclides (RN) within the geological barrier of a radioactive waste repository requires, amongst other data, the introduction of reliable transport parameters, as diffusion coefficients. Since the determination of diffusion coefficients within crystalline rocks is complex and requires long experimental times even for non-sorbing radionuclides, the data available in the literature are very scarce. The nuclear ion beam technique RBS (Rutherford Backscattering Spectrometry) that is successfully used to determine diffusion profiles in thin film science is here examined as possible suitable technique to determine the diffusion coefficients of different RN within granite. As first step, the technique sensitivity and limitations to analyse diffusion coefficients in granite samples is evaluated, considering that the technique is especially sensitive to heavy elements. The required experimental conditions in terms of experimental times, concentration and methodology of analysis are discussed. The diffusants were selected accounting the RBS sensitivity but also trying to cover different behaviours of critical RN and a wide range of possible oxidation states. In particular, Cs(I) was chosen as representative fission product, while as relevant actinides or homologues, the diffusion of Th(IV), U(IV) and Eu (III) was studied. The diffusion of these above-mentioned cations is compared to the diffusion of Re, and I as representative of anionic species. The methodology allowed evaluating diffusion coefficients in the granite samples and, for most of the elements, the values obtained are in agreement with the values found in the literature. The diffusion coefficients calculated ranged from 10 -13 to 10 -16 m 2 /s. It is remarkable that the RBS technique is especially promising to determine diffusion coefficients of high-sorbing RN and it is applicable to a wide range

  4. Diffusion

    International Nuclear Information System (INIS)

    Kubaschewski, O.

    1983-01-01

    The diffusion rate values of titanium, its compounds and alloys are summarized and tabulated. The individual chemical diffusion coefficients and self-diffusion coefficients of certain isotopes are given. Experimental methods are listed which were used for the determination of diffusion coefficients. Some values have been taken over from other studies. Also given are graphs showing the temperature dependences of diffusion and changes in the diffusion coefficient with concentration changes

  5. Evaluation Technique of Chloride Penetration Using Apparent Diffusion Coefficient and Neural Network Algorithm

    Directory of Open Access Journals (Sweden)

    Yun-Yong Kim

    2014-01-01

    Full Text Available Diffusion coefficient from chloride migration test is currently used; however this cannot provide a conventional solution like total chloride contents since it depicts only ion migration velocity in electrical field. This paper proposes a simple analysis technique for chloride behavior using apparent diffusion coefficient from neural network algorithm with time-dependent diffusion phenomena. For this work, thirty mix proportions of high performance concrete are prepared and their diffusion coefficients are obtained after long term-NaCl submerged test. Considering time-dependent diffusion coefficient based on Fick’s 2nd Law and NNA (neural network algorithm, analysis technique for chloride penetration is proposed. The applicability of the proposed technique is verified through the results from accelerated test, long term submerged test, and field investigation results.

  6. Modeling and experiments for the time-dependent diffusion coefficient during methane desorption from coal

    Science.gov (United States)

    Cheng-Wu, Li; Hong-Lai, Xue; Cheng, Guan; Wen-biao, Liu

    2018-04-01

    Statistical analysis shows that in the coal matrix, the diffusion coefficient for methane is time-varying, and its integral satisfies the formula μt κ /(1 + β κ ). Therefore, a so-called dynamic diffusion coefficient model (DDC model) is developed. To verify the suitability and accuracy of the DDC model, a series of gas diffusion experiments were conducted using coal particles of different sizes. The results show that the experimental data can be accurately described by the DDC and bidisperse models, but the fit to the DDC model is slightly better. For all coal samples, as time increases, the effective diffusion coefficient first shows a sudden drop, followed by a gradual decrease before stabilizing at longer times. The effective diffusion coefficient has a negative relationship with the size of the coal particle. Finally, the relationship between the constants of the DDC model and the effective diffusion coefficient is discussed. The constant α (μ/R 2 ) denotes the effective coefficient at the initial time, and the constants κ and β control the attenuation characteristic of the effective diffusion coefficient.

  7. Fe+3 diffusion coefficient in Fricke xylenol gel through shielding half of a 6 MV photon beam field size

    International Nuclear Information System (INIS)

    Cavalcante, Fernanda; Oliveira, Lucas de; Almeida, Adelaide de

    2009-01-01

    Diffusion of ions can be observed in a solution or gel when a difference occurs in their concentrations. For dosimetric gels, the diffusion can interfere on measurements of absorbed dose delivered to the patient in a radiotherapic treatment, when the time interval for measurements pos-irradiation is considered long. In the present work, a pos-irradiation Fricke Xylenol Gel (FXG) spatial dose distribution was obtained for several time intervals and the diffusion coefficient was inferred following a literature theoretical methodology. Using FXG samples, whose [Fe 2+ ] are oxidated to [Fe +3 ] when irradiated, the diffusion coefficient for the last ion was obtained in order that one can have the real spatial dose distribution right after the irradiation and this was done using half shielded 6 MV photons field size. Each sample, for each time interval selected (from 2.8 up to 28.6 hours) was analyzed in function of their optical absorbance. From Fick's law and from an error equation, the diffusion coefficient was inferred, which can be used to correct the absorbance positions promptly after irradiation. The diffusion coefficient found for the FXG dosimeter, has the value of 0.452 mm 2 /h, that is between the interval of 0.3 up to 2.0 mm 2 /h, predicted for gel type dosimeters. (author)

  8. DETERMINATION OF MOISTURE DIFFUSION COEFFICIENT OF LARCH BOARD WITH FINITE DIFFERENCE METHOD

    Directory of Open Access Journals (Sweden)

    Qiaofang Zhou

    2011-04-01

    Full Text Available This paper deals with the moisture diffusion coefficient of Dahurian Larch (Larix gmelinii Rupr. by use of the Finite Difference Method (FDM. To obtain moisture distributions the dimensional boards of Dahurian Larch were dried, from which test samples were cut and sliced evenly into 9 pieces in different drying periods, so that moisture distributions at different locations and times across the thickness of Dahurian Larch were obtained with a weighing method. With these experimental data, FDM was used to solve Fick’s one-dimensional unsteady-state diffusion equation, and the moisture diffusion coefficient across the thickness at specified time was obtained. Results indicated that the moisture diffusion coefficient decreased from the surface to the center of the Dahurian Larch wood, and it decreased with decreasing moisture content at constant wood temperature; as the wood temperature increased, the moisture diffusion coefficient increased, and the effect of the wood temperature on the moisture diffusion coefficient was more significant than that of moisture content. Moisture diffusion coefficients were different for the two experiments due to differing diffusivity of the specimens.

  9. An improved procedure for determining grain boundary diffusion coefficients from averaged concentration profiles

    Science.gov (United States)

    Gryaznov, D.; Fleig, J.; Maier, J.

    2008-03-01

    Whipple's solution of the problem of grain boundary diffusion and Le Claire's relation, which is often used to determine grain boundary diffusion coefficients, are examined for a broad range of ratios of grain boundary to bulk diffusivities Δ and diffusion times t. Different reasons leading to errors in determining the grain boundary diffusivity (DGB) when using Le Claire's relation are discussed. It is shown that nonlinearities of the diffusion profiles in lnCav-y6/5 plots and deviations from "Le Claire's constant" (-0.78) are the major error sources (Cav=averaged concentration, y =coordinate in diffusion direction). An improved relation (replacing Le Claire's constant) is suggested for analyzing diffusion profiles particularly suited for small diffusion lengths (short times) as often required in diffusion experiments on nanocrystalline materials.

  10. A study on the determination of diffusion coefficient of carbon in 304 austenitic stainless steels by internal friction method

    International Nuclear Information System (INIS)

    Kim, K.S.; Kim, T.H.

    1982-01-01

    Internal friction peaks associated with the presence of carbon in 18-8 type 304 stainless steel have been observed from measurements with a torsion pendulum. The temperature for maximum internal friction lies between 250degC and 300degC with a frequency of vibration. The height of the peak rises and the position of the peak shifts to a lower temperature with an increase of the carbon content. And a comparison of the activation energy and the diffusion coefficient determined by internal friction methods with those measured in conventional macro-diffusion experiments reveals that the diffusion data measured by internal friction method and the diffusion data measured by conventional method exist in the same line. It follows from the above fact that observed internal friction peak is associated with the stress-induced diffusion of carbon in face-centered cubic alloys. (Author)

  11. EVOLUTION OF THE MAGNETIC FIELD LINE DIFFUSION COEFFICIENT AND NON-GAUSSIAN STATISTICS

    Energy Technology Data Exchange (ETDEWEB)

    Snodin, A. P. [Department of Mathematics, Faculty of Applied Science, King Mongkut’s University of Technology North Bangkok, Bangkok 10800 (Thailand); Ruffolo, D. [Department of Physics, Faculty of Science, Mahidol University, Bangkok 10400 (Thailand); Matthaeus, W. H. [Bartol Research Institute and Department of Physics and Astronomy, University of Delaware, Newark, DE 19716 (United States)

    2016-08-20

    The magnetic field line random walk (FLRW) plays an important role in the transport of energy and particles in turbulent plasmas. For magnetic fluctuations that are transverse or almost transverse to a large-scale mean magnetic field, theories describing the FLRW usually predict asymptotic diffusion of magnetic field lines perpendicular to the mean field. Such theories often depend on the assumption that one can relate the Lagrangian and Eulerian statistics of the magnetic field via Corrsin’s hypothesis, and additionally take the distribution of magnetic field line displacements to be Gaussian. Here we take an ordinary differential equation (ODE) model with these underlying assumptions and test how well it describes the evolution of the magnetic field line diffusion coefficient in 2D+slab magnetic turbulence, by comparisons to computer simulations that do not involve such assumptions. In addition, we directly test the accuracy of the Corrsin approximation to the Lagrangian correlation. Over much of the studied parameter space we find that the ODE model is in fairly good agreement with computer simulations, in terms of both the evolution and asymptotic values of the diffusion coefficient. When there is poor agreement, we show that this can be largely attributed to the failure of Corrsin’s hypothesis rather than the assumption of Gaussian statistics of field line displacements. The degree of non-Gaussianity, which we measure in terms of the kurtosis, appears to be an indicator of how well Corrsin’s approximation works.

  12. Desorption modeling of hydrophobic organic chemicals from plastic sheets using experimentally determined diffusion coefficients in plastics.

    Science.gov (United States)

    Lee, Hwang; Byun, Da-Eun; Kim, Ju Min; Kwon, Jung-Hwan

    2018-01-01

    To evaluate rate of migration from plastic debris, desorption of model hydrophobic organic chemicals (HOCs) from polyethylene (PE)/polypropylene (PP) films to water was measured using PE/PP films homogeneously loaded with the HOCs. The HOCs fractions remaining in the PE/PP films were compared with those predicted using a model characterized by the mass transfer Biot number. The experimental data agreed with the model simulation, indicating that HOCs desorption from plastic particles can generally be described by the model. For hexachlorocyclohexanes with lower plastic-water partition coefficients, desorption was dominated by diffusion in the plastic film, whereas desorption of chlorinated benzenes with higher partition coefficients was determined by diffusion in the aqueous boundary layer. Evaluation of the fraction of HOCs remaining in plastic films with respect to film thickness and desorption time showed that the partition coefficient between plastic and water is the most important parameter influencing the desorption half-life. Copyright © 2017 Elsevier Ltd. All rights reserved.

  13. Self-diffusion coefficients of the metastable Lennard-Jones vapor

    International Nuclear Information System (INIS)

    Nie Chu; Zhou Youhua; Marlow, W H; Hassan, Y A

    2008-01-01

    Self-diffusion coefficients of a metastable Lennard-Jones vapor were obtained using the memory function formalism and the frequency moments of the velocity autocorrelation function at reduced temperatures from 0.75 to 1.0. The radial density distribution functions used to evaluate the second, fourth and sixth frequency moments of the velocity autocorrelation function were obtained from the restricted canonical ensemble Monte Carlo simulation (Corti and Debenedetti 1994 Chem. Eng. Sci. 49 2717). The self-diffusion coefficients at reduced temperature 0.75 do not vary monotonically as the density increases, and for the other three temperatures the self-diffusion coefficients vary normally

  14. Self-diffusion coefficients of the metastable Lennard-Jones vapor

    Energy Technology Data Exchange (ETDEWEB)

    Nie Chu; Zhou Youhua [School of Physics and Information Engineering, Jianghan University, Wuhan 430056 (China); Marlow, W H; Hassan, Y A [Department of Nuclear Engineering, Texas A and M University, College Station, TX 77843 (United States)], E-mail: yhzhou@jhun.edu.cn

    2008-10-15

    Self-diffusion coefficients of a metastable Lennard-Jones vapor were obtained using the memory function formalism and the frequency moments of the velocity autocorrelation function at reduced temperatures from 0.75 to 1.0. The radial density distribution functions used to evaluate the second, fourth and sixth frequency moments of the velocity autocorrelation function were obtained from the restricted canonical ensemble Monte Carlo simulation (Corti and Debenedetti 1994 Chem. Eng. Sci. 49 2717). The self-diffusion coefficients at reduced temperature 0.75 do not vary monotonically as the density increases, and for the other three temperatures the self-diffusion coefficients vary normally.

  15. Investigation of a phantom for diffusion weighted imaging that controlled the apparent diffusion coefficient using gelatin and sucrose

    International Nuclear Information System (INIS)

    Tamura, Takayuki; Usui, Shuji; Akiyama, Mitoshi

    2009-01-01

    When studying diffusion weighted imaging (DWI), it is important to create a phantom that has a reliably controlled diffusion coefficient. In this study, we investigated phantoms to control both the diffusion coefficient and the T2-value by changing the concentration of gelatin or sucrose and MnCl 2 , respectively. The results showed that the diffusion coefficient decreased linearly with increases in the gelatin or sucrose concentration, and decreasing of their relaxation times was observed. By properly adjusting the MnCl 2 concentrations, we were able to equalize the T2-values between phantoms having different gelatin or sucrose concentrations. Temperature dependence of the diffusion coefficient was also revealed. This phantom can be made stable for a few months by adding a small amount of NaN 3 as an antiseptic agent, has a diffusion coefficient similar to that of neural tissue or clinical tumor, and is able to control the T2-value properly. We consider this phantom suitable for studying SE-type DWI and contributes to elucidation of this technique. (author)

  16. Banded Structures in Electron Pitch Angle Diffusion Coefficients from Resonant Wave Particle Interactions

    Science.gov (United States)

    Tripathi, A. K.; Singhal, R. P.; Khazanov, G. V.; Avanov, L. A.

    2016-01-01

    Electron pitch angle (D (alpha)) and momentum (D(pp)) diffusion coefficients have been calculated due to resonant interactions with electrostatic electron cyclotron harmonic (ECH) and whistler mode chorus waves. Calculations have been performed at two spatial locations L = 4.6 and 6.8 for electron energies 10 keV. Landau (n = 0) resonance and cyclotron harmonic resonances n = +/-1, +/-2,...+/-5 have been included in the calculations. It is found that diffusion coefficient versus pitch angle (alpha) profiles show large dips and oscillations or banded structures. The structures are more pronounced for ECH and lower band chorus (LBC) and particularly at location 4.6. Calculations of diffusion coefficients have also been performed for individual resonances. It is noticed that the main contribution of ECH waves in pitch angle diffusion coefficient is due to resonances n = +1 and n = +2. A major contribution to momentum diffusion coefficients appears from n = +2. However, the banded structures in D alpha and Dpp coefficients appear only in the profile of diffusion coefficients for n = +2. The contribution of other resonances to diffusion coefficients is found to be, in general, quite small or even negligible. For LBC and upper band chorus waves, the banded structures appear only in Landau resonance. The Dpp diffusion coefficient for ECH waves is one to two orders smaller than D alpha coefficients. For chorus waves, Dpp coefficients are about an order of magnitude smaller than D alpha coefficients for the case n does not = 0. In case of Landau resonance, the values of Dpp coefficient are generally larger than the values of D alpha coefficients particularly at lower energies. As an aid to the interpretation of results, we have also determined the resonant frequencies. For ECH waves, resonant frequencies have been estimated for wave normal angle 89 deg and harmonic resonances n = +1, +2, and +3, whereas for whistler mode waves, the frequencies have been calculated for angle

  17. Banded Structures in Electron Pitch Angle Diffusion Coefficients from Resonant Wave-Particle Interactions

    Science.gov (United States)

    Tripathi, A. K.; Singhal, R. P.; Khazanov, G. V.; Avanov, L. A.

    2016-01-01

    Electron pitch angle (D(sub (alpha alpha))) and momentum (D(sub pp)) diffusion coefficients have been calculated due to resonant interactions with electrostatic electron cyclotron harmonic (ECH) and whistler mode chorus waves. Calculations have been performed at two spatial locations L=4.6 and 6.8 for electron energies less than or equal to 10 keV. Landau (n=0) resonance and cyclotron harmonic resonances n= +/- 1, +/-2, ... +/-5 have been included in the calculations. It is found that diffusion coefficient versus pitch angle (alpha) profiles show large dips and oscillations or banded structures. The structures are more pronounced for ECH and lower band chorus (LBC) and particularly at location 4.6. Calculations of diffusion coefficients have also been performed for individual resonances. It is noticed that the main contribution of ECH waves in pitch angle diffusion coefficient is due to resonances n=+1 and n=+2. A major contribution to momentum diffusion coefficients appears from n=+2. However, the banded structures in D(sub alpha alpha) and D(sub pp) coefficients appear only in the profile of diffusion coefficients for n=+2. The contribution of other resonances to diffusion coefficients is found to be, in general, quite small or even negligible. For LBC and upper band chorus waves, the banded structures appear only in Landau resonance. The D(sub pp) diffusion coefficient for ECH waves is one to two orders smaller than D(sub alpha alpha) coefficients. For chorus waves, D(sub pp) coefficients are about an order of magnitude smaller than D(sub alpha alpha) coefficients for the case n does not equal 0. In case of Landau resonance, the values of D(sub pp) coefficient are generally larger than the values of D(sub alpha alpha) coefficients particularly at lower energies. As an aid to the interpretation of results, we have also determined the resonant frequencies. For ECH waves, resonant frequencies have been estimated for wave normal angle 89 deg and harmonic resonances

  18. Affection of blood supply of focal hepatic mass on apparent diffusion coefficient of the lesions

    International Nuclear Information System (INIS)

    Chen Zaizhi; Wu Yulin; Xu Zhongfei; Yang Zhenghan; Chen Min; Zhou Cheng; Xie Jingxia

    2002-01-01

    Objective: To investigate the affection of lesion blood supply on apparent diffusion coefficient (ADC) of focal hepatic mass. Methods: Diffusion-weighted imaging (DWI) with different b values was performed in 87 patients with 159 focal hepatic lesions. ADCs of lesion, liver, spleen, gallbladder were measured in every case. Results: On DWI with small b value and small b value remainder, ADCs were affected by blood perfusion of tissues or lesions. The mean ADC of hypervascular lesions was significantly higher than that of hypovascular lesions on DWI with small b value, and hemoangiomas got the highest mean ADC. The mean ADC of hepatic cysts was not affected by b value. Conclusion: Blood perfusion affects ADC of tissue or focal hepatic lesion, particularly on DWI with small b value, and to some degree, DWI and ADC can reflect the blood supply of focal hepatic lesion

  19. Evaluation of the diffusion coefficient of fluorine during the electropolishing of niobium

    Directory of Open Access Journals (Sweden)

    Hui Tian

    2010-08-01

    Full Text Available Future accelerators require unprecedented cavity performance, which is strongly influenced by interior surface nanosmoothness. Electropolishing (EP is the technique of choice being developed for high-field superconducting radio frequency (SRF cavities. Previous study has shown that the mechanism of Nb electropolishing proceeds by formation and dissolution of a compact salt film under fluorine diffusion-limited mass transport control. We pursue an improved understanding of the microscopic conditions required for optimum surface finishing. The viscosity of the standard electrolyte has been measured using a commercial viscometer, and the diffusion coefficient of fluorine was derived at a variety of temperatures from 0 to 50°C using a Nb rotating disk electrode. In addition, data indicate that electrode kinetics becomes competitive with the mass transfer current limitation and increases dramatically with temperature. These findings are expected to guide the optimization of EP process parameters for achieving controlled, reproducible, and uniform nanosmooth surface finishing of SRF cavities.

  20. Oxygen Chemical Diffusion Coefficients of (Pu,Am)O2 Fuels

    International Nuclear Information System (INIS)

    Watanabe, M.; Kato, M.; Matsumoto, T.

    2015-01-01

    Minor actinide (MA)-bearing MOX fuels have been developed as candidate fuels which are used in fast neutron spectrum cores such as sodium-cooled fast reactor (SFR) cores and experimental accelerator driven system (ADS) cores. Americium (Am) which is one of the MA elements significantly affects basic properties. It is known that Am content causes oxygen potential to increase and that influences irradiation behaviour such as fuel-cladding chemical interaction (FCCI) and chemical state of fission products. However, the effects of Am content on changes of basic properties are not clear. In this work, the oxygen chemical diffusion coefficients were calculated from measured data and the relationship between oxygen diffusion and oxygen potential of (Pu,Am)O 2-x was discussed. (authors)

  1. Preliminary evaluation of the apparent diffusion coefficient of the kidney with a spiral IVIM sequence

    International Nuclear Information System (INIS)

    Tsuda, Kyo; Murakami, Takamichi; Sakurai, Kousuke

    1997-01-01

    We examined the usefulness of the spiral intravoxel incoherent motion (IVIM) sequence in measuring the apparent diffusion coefficient (ADC) of the kidneys. Five volunteers and five patients with chronic renal failure underwent diffusion-sensitive magnetic resonance imaging of the kidneys with the spiral IVIM sequence. The ADC values in patients with chronic renal failure were significantly lower than those in the renal cortex of volunteers. The mean value of ADC in patients with chronic renal failure was lower than that in volunteers, although there was no statistically significant difference. In volunteers, the ADC of the renal cortex was significantly higher than that of the renal medulla. The phantom study indicated that the accuracy of ADC depended on the signal to noise ratio. A spiral IVIM sequence with a high enough signal to noise ratio may be useful in evaluating renal function, especially that of the cortex. (author)

  2. Evaluation of Particle Pinch and Diffusion Coefficients in the Edge Pedestal of DIII-D H-mode Discharges

    Science.gov (United States)

    Stacey, W. M.; Groebner, R. J.

    2009-11-01

    Momentum balance requires that the radial particle flux satisfy a pinch-diffusion relationship. The pinch can be evaluated in terms of measurable quantities (rotation velocities, Er, etc.) by the use of momentum and particle balance [1,2], the radial particle flux can be determined by momentum balance, and then the diffusion coefficient can be evaluated from the pinch diffusion relation using the measured density gradient. Applications to several DIII-D H-mode plasmas are presented. 6pt [1] W.M. Stacey, Contr. Plasma Phys. 48, 94 (2008). [2] W.M. Stacey and R.J. Groebner, Phys. Plasmas 15, 012503 (2008).

  3. Alterations of apparent diffusion coefficient (ADC) in the brain of rats chronically exposed to lead acetate.

    Science.gov (United States)

    López-Larrubia, Pilar; Cauli, Omar

    2011-03-15

    Diffusion-weighted imaging (DWI) allows the assessment of the water apparent diffusion coefficient (ADC), a measure of tissue water diffusivity which is altered during different pathological conditions such as cerebral oedema. By means of DWI, we repeatedly measured in the same rats apparent diffusion coefficient ADC in different brain areas (motor cortex (MCx), somato-sensory cortex (SCx), caudate-putamen (CPu), hippocampus (Hip), mesencephalic reticular formation (RF), corpus callosum (CC) and cerebellum (Cb)) after 1 week, 4 and 12 weeks of lead acetate exposure via drinking water (50 or 500 ppm). After 12 weeks of lead exposure rats received albumin-Evans blue complex administration and were sacrificed 1h later. Blood-brain barrier permeability and water tissue content were determined in order to evaluate their relationship with ADC changes. Chronic exposure to lead acetate (500 ppm) for 4 weeks increased ADC values in Hip, RF and Cb but no in other brain areas. After 12 weeks of lead acetate exposure at 500 ppm ADC is significantly increased also in CPu and CC. Brain areas displaying high ADC values after lead exposure showed also an increased water content and increased BBB permeability to Evans blue-albumin complex. Exposure to 50 ppm for 12 weeks increased ADC values and BBB permeability in the RF and Cb. In summary, chronic lead exposure induces cerebral oedema in the adult brain depending on the brain area and the dose of exposure. RF and Cb appeared the most sensitive brain areas whereas cerebral cortex appears resistant to lead-induced cerebral oedema. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  4. Contribution to the evaluation of diffusion coefficients in plasmas containing argon and fluorine

    International Nuclear Information System (INIS)

    Novakovic, N V

    2006-01-01

    The theoretical values of the numerical evaluation of the electron and ion diffusion coefficients in plasmas from mixtures of argon and fluorine are presented. The temperature dependence of the diffusion coefficients for low-pressure (from 0.1 to 1.0 kPa) and low-temperature (from 500 to 5000 K) argon plasmas with 20% and 30% of added fluorine are investigated. These values are results of the applications of the specific numerical model to the evaluation plasma composition and transport coefficients in argon plasma with fluorine as additive. It is assumed that the system is kept under constant pressure and that a corresponding state of local thermodynamical equilibrium (LTE) is attained. Since the LTE can be assumed, a Maxwellian electron distribution function will be adopted. The hypothesis of LTE, which is commonly used in most of the numerical evaluations, is analysed with the modified Debye radius r D *. The binary electron and ion diffusion coefficients are calculated with the equilibrium plasma composition and with the collision frequencies. Strictly speaking, Maxwellian distribution function (in the state LTE) is not valid for low pressure, but in this case with the aid of the modified Debye radius, a Maxwellian f e M is assumed correctly. It is shown that the electron diffusion coefficients are about four orders of magnitude larger than the corresponding overall diffusion coefficients of ions. Both diffusion coefficients are lower in argon plasma with 30% than with 20% of fluorine additives, in the whole temperature range examined

  5. A method for the determination of gas diffusion coefficients in undisturbed Boom Clay

    International Nuclear Information System (INIS)

    Jacops, E.; Volckaert, G.; Maes, N.; Weetjens, E.; Maes, T.; Vandervoort, F.

    2010-01-01

    kind of a through diffusion test with dissolved gasses. A clay core is sealed in a stainless steel cell and connected at both sides with water vessels that are pressurized with 2 different gasses at the same pressure. In this way no advective gas flux can occur and the clay sample remains fully water saturated. The water at both sides is pumped around. Gas dissolves into the water and because of the gas concentration gradient, these dissolved gasses diffuse through the clay. The dissolved gas that diffuses into the other water vessel will equilibrate with the gas atmosphere and the changes in the gas composition can be determined through e.g. gas chromatography. As such, the diffusion parameters of two gasses can be determined in a single experiment. Tests will be conducted with the following gas combinations: He and Ar, He and CH 4 , Ar and Hytec (5% H 2 in Ar). These tests are interpreted with a simple diffusive transport model. The model solves the diffusive transport equation in a 1D geometry. The porosity of the clay core is set to 30%. At one end, a fixed gas concentration was imposed as boundary condition, corresponding to the dissolved fraction at the prevalent pressure in the vessel following Henry's law. At the other end, the concentration of the considered gas is assumed to be 0. As model output, fluxes at both faces, as well as concentration profiles at regular time intervals are obtained. For both He and CH 4 the evolution of the measured gas concentrations in the downstream vessel for each gas fall within simulation curves using rather narrow ranges of the Dapp: 1.4 - 1.6 10 -10 m 2 /s for He and 2.5 - 3 10 -10 m 2 /s for CH 4 . It is clear that the method is very sensitive and that quite accurate measurements of the diffusion coefficients can be obtained, far better than the previous results obtained in the MEGAS project. Currently an experiment to determine the diffusion coefficient for hydrogen is on-going. This method allows for an accurate

  6. Study on pore structure and diffusion coefficient of chloride ion in hardened low-alkaline cement

    International Nuclear Information System (INIS)

    Mihara, Morihiro; Torii, Kazuyuki

    2009-03-01

    Low-alkaline cement using pozzolans is under consideration as a possible filling and structural material in geological disposal for long-lived radioactive waste. Silica fume and fly ash are used to develop the low-alkaline cement which is named HFSC, High-volume Fly ash Silica fume Cement. In this study, pore structure and diffusivity of chloride ion in HFSC pastes were investigated in order to understand the fundamental transport properties of ions. HFSC which included different contents of fly ash (40%, 50% and 60%) with silica fume (20%) and ordinary Portland (OPC) cement were prepared. Hardened cement pastes were supplied to pore structure analysis and in-diffusion experiment with NaCl and CaCl 2 solution. Mercury intrusion method (MIP) commonly used and image analysis of backscattered electron microscopy (BSE) for pore in hardened cement paste were performed to investigate the pore structure. The porosity of HFSC was larger than that of OPC measured by MIP. However, pore diameter increasing pore volume of HFSC was smaller than that of OPC. It was observed that lager pores were in HFSC than in OPC from BSE. These large pores in HFSC were originated from cenosphere of FA. The apparent diffusivity of chloride in HFSC with fly ash of 40% showed smallest value in the cement pastes. It was concluded that the smallest diffusion coefficient was caused by a pore of HFSC which had a bended structure and ion exclusion/filtration effect. (author)

  7. Colorectal liver metastases: contrast agent diffusion coefficient for quantification of contrast enhancement heterogeneity at MR imaging.

    Science.gov (United States)

    Jia, Guang; O'Dell, Craig; Heverhagen, Johannes T; Yang, Xiangyu; Liang, Jiachao; Jacko, Richard V; Sammet, Steffen; Pellas, Theodore; Cole, Patricia; Knopp, Michael V

    2008-09-01

    To describe and determine the reproducibility of a simplified model to quantitatively measure heterogeneous intralesion contrast agent diffusion in colorectal liver metastases. This HIPAA-compliant retrospective study received institutional review board approval, and written informed consent was obtained from 14 patients (mean age, 61 years +/- 9 [standard deviation]; range, 41-78 years), including 10 men (mean age, 65 years +/- 8; range, 47-78 years) and four women (mean age, 54 years +/- 9; range, 41-59 years), with colorectal liver metastases. Magnetic resonance (MR) imaging was performed twice (first baseline MR image [B(1)] and second baseline MR image [B(2)]) in a single target lesion prior to therapy. Dynamic contrast material-enhanced MR imaging was performed by using a saturation-recovery fast gradient-echo sequence. A simplified contrast agent diffusion model was proposed, and a contrast agent diffusion coefficient (CDC) was calculated. The reproducibility of the CDC measurement was evaluated by using the Bland-Altman plot and a linear regression model. The mean CDC was 0.22 mm(2)/sec (range, 0.01-0.73 mm(2)/sec) on B(1) and 0.24 mm(2)/sec (range, 0.01-0.71 mm(2)/sec) on B(2), with an intraclass correlation coefficient of 0.91 (P < .0001). Bland-Altman plot showed good agreement, with a mean difference in measurement pairs of 0.017 mm(2)/sec +/- 0.096. The slope from the linear regression model was 0.89 (95% confidence interval: 0.63, 1.15) and the intercept was 0.01 (95% confidence interval: -0.08, 0.09). The CDC enables a quantitative description of contrast enhancement heterogeneity in lesions. Given the high reproducibility of the CDC metric, CDC appears promising for further qualification as an imaging biomarker of change measurement in response assessment. http://radiology.rsnajnls.org/cgi/content/full/248/3/901/DC1. RSNA, 2008

  8. Apparent diffusion coefficient histogram analysis of neonatal hypoxic-ischemic encephalopathy

    International Nuclear Information System (INIS)

    Cauley, Keith A.; Filippi, Christopher G.

    2014-01-01

    Diffusion-weighted imaging is a valuable tool in the assessment of the neonatal brain, and changes in diffusion are seen in normal development as well as in pathological states such as hypoxic-ischemic encephalopathy (HIE). Various methods of quantitative assessment of diffusion values have been reported. Global ischemic injury occurring during the time of rapid developmental changes in brain myelination can complicate the imaging diagnosis of neonatal HIE. To compare a quantitative method of histographic analysis of brain apparent coefficient (ADC) maps to the qualitative interpretation of routine brain MR imaging studies. We correlate changes in diffusion values with gestational age in radiographically normal neonates, and we investigate the sensitivity of the method as a quantitative measure of hypoxic-ischemic encephalopathy. We reviewed all brain MRI studies from the neonatal intensive care unit (NICU) at our university medical center over a 4-year period to identify cases that were radiographically normal (23 cases) and those with diffuse, global hypoxic-ischemic encephalopathy (12 cases). We histographically displayed ADC values of a single brain slice at the level of the basal ganglia and correlated peak (s-sD av ) and lowest histogram values (s-sD lowest ) with gestational age. Normative s-sD av values correlated significantly with gestational age and declined linearly through the neonatal period (r 2 = 0.477, P av and s-sD lowest ADC values than were reflected in the normative distribution; several cases of HIE fell within a 95% confidence interval for normative studies, and one case demonstrated higher-than-normal s-sD av . Single-slice histographic display of ADC values is a rapid and clinically feasible method of quantitative analysis of diffusion. In this study normative values derived from consecutive neonates without radiographic evidence of ischemic injury are correlated with gestational age, declining linearly throughout the perinatal period. This

  9. Early Changes in Apparent Diffusion Coefficient From Diffusion-Weighted MR Imaging During Radiotherapy for Prostate Cancer

    International Nuclear Information System (INIS)

    Park, Sung Yoon; Kim, Chan Kyo; Park, Byung Kwan; Park, Won; Park, Hee Chul; Han, Deok Hyun; Kim, Bohyun

    2012-01-01

    Purpose: To investigate the feasibility of diffusion-weighted MRI (DWI) as an early and reproducible change indicator in patients receiving radiotherapy for prostate cancer (PC). Methods and Materials: Eight consecutive patients with biopsy-proven PC underwent DWI at 3T. All patients who received external-beam radiotherapy had four serial MR scans, as follows: before therapy (PreTx); after 1 week of therapy (PostT1); after 3 weeks of therapy (PostT2); and 1 month after the completion of therapy (PostT3). At each time, the apparent diffusion coefficient (ADC) was measured in tumors and normal tissues. For reproducibility of the ADC measurement, five patients also had two separate pretreatment DWI scans at an interval of −3 mm 2 /s in sequence, respectively. Compared with PreTx, PostT1 (p = 0.005), PostT2 (p = 0.003), and PostT3 (p −3 mm 2 /s in sequence, respectively. Reproducibility of ADC measurements was confirmed with a mean difference in ADC of –0.04 in peripheral zone and –0.017 in transition zone between two separate pretreatment MR scans. The mean PSA levels from PreTx to PostT3 were 9.05, 9.18, 9.25, and 4.11 ng/mL in sequence, respectively. Conclusions: DWI, as a reproducible biomarker, has the potential to evaluate the early therapeutic changes of PC to radiotherapy.

  10. Determination of the concentration dependent diffusion coefficient of nitrogen in expanded austenite

    DEFF Research Database (Denmark)

    Christiansen, Thomas; Somers, Marcel A. J.

    2008-01-01

    The concentration dependent diffusion coefficient of nitrogen in expanded austenite was determined from of the rate of retracting nitrogen from thin initially N-saturated coupons. Nitrogen saturated homogeneous foils of expanded austenite were obtained by nitriding AISI 304 and AISI 316 in pure...... in the composition range where nitrogen can be extracted by hydrogen gas at the diffusion temperature. Numerical simulation of the denitriding experiments shows that the thus determined concentration dependent diffusion coefficients are an accurate approximation of the actual diffusivity of nitrogen in expanded...... ammonia at 693 K and 718 K. Denitriding experiments were performed by equilibrating the foils with a successively lower nitrogen activity, as imposed by a gas mixture of ammonia and hydrogen. The concentration dependent diffusion coefficient of nitrogen in expanded austenite was approximated...

  11. Multitracer method of diffusion measurement in chromium-manganese steels

    International Nuclear Information System (INIS)

    Dudala, J.; Stegowski, Z.; Gilewicz-Wolter, J.

    2004-01-01

    The paper presents an application of multitracer method to diffusion measurement in Cr-Mn steels. Radioisotope tracers of chromium 51 Cr, manganese 54 Mn and iron 59 Fe were used simultaneously in the diffusion process, Gamma-spectrum measurement and the proper analysis enabled evaluation of concentration distribution for each tracer. As a new tool, artificial neural networks (ANN) method was used for spectrum analysis. The proper solution of the diffusion model was applied to the experimental tracers' distribution data and diffusion coefficients were determined. (author)

  12. Diffusion coefficient and Kolmogorov entropy of magnetic field lines

    International Nuclear Information System (INIS)

    Zimbardo, G.; Veltri, P.; Malara, F.

    1984-01-01

    A diffusion equation for magnetic field lines of force in a turbulent magnetic field, which describes both the random walk of a single line and how two nearby lines separate from each other, has been obtained using standard statistical techniques. Starting from such an equation, a closed set of equations for the moments may be obtained, in general, with suitable assumptions. From such a set of equations the Kolmogorov entropy may be explicitly calculated. The results have been applied to the most interesting examples of magnetic field geometries. (author)

  13. FITTING OF THE DATA FOR DIFFUSION COEFFICIENTS IN UNSATURATED POROUS MEDIA

    Energy Technology Data Exchange (ETDEWEB)

    B. Bullard

    1999-05-01

    The purpose of this calculation is to evaluate diffusion coefficients in unsaturated porous media for use in the TSPA-VA analyses. Using experimental data, regression techniques were used to curve fit the diffusion coefficient in unsaturated porous media as a function of volumetric water content. This calculation substantiates the model fit used in Total System Performance Assessment-1995 An Evaluation of the Potential Yucca Mountain Repository (TSPA-1995), Section 6.5.4.

  14. FITTING OF THE DATA FOR DIFFUSION COEFFICIENTS IN UNSATURATED POROUS MEDIA

    International Nuclear Information System (INIS)

    B. Bullard

    1999-01-01

    The purpose of this calculation is to evaluate diffusion coefficients in unsaturated porous media for use in the TSPA-VA analyses. Using experimental data, regression techniques were used to curve fit the diffusion coefficient in unsaturated porous media as a function of volumetric water content. This calculation substantiates the model fit used in Total System Performance Assessment-1995 An Evaluation of the Potential Yucca Mountain Repository (TSPA-1995), Section 6.5.4

  15. The effect of radionuclides and their carriers on diffusion coefficient of radionuclides in local rocks

    International Nuclear Information System (INIS)

    Othman, I.; Takriti, S.

    1995-07-01

    The diffusion coefficient of sup 9 sup 0 Sr and sup 1 sup 3 sup 7 Cs has been calculated for different local rocks in stationary and dynamic state. The effect of pH radioisotope solution dependence in shown by diffusion coefficient in some rocks. The results show that the cement and dolomite have the best quality of radioisotope retention which do not allow them to pollute the environment. (author). 6 refs., 2 tabs., 13 figs

  16. Diffusion coefficients for multi-step persistent random walks on lattices

    International Nuclear Information System (INIS)

    Gilbert, Thomas; Sanders, David P

    2010-01-01

    We calculate the diffusion coefficients of persistent random walks on lattices, where the direction of a walker at a given step depends on the memory of a certain number of previous steps. In particular, we describe a simple method which enables us to obtain explicit expressions for the diffusion coefficients of walks with a two-step memory on different classes of one-, two- and higher dimensional lattices.

  17. The use of CACTUS to generate modified diffusion coefficients in LWRWIMS

    International Nuclear Information System (INIS)

    Halsall, M.J.

    1986-11-01

    A new method has been devised in the lattice code, LWRWIMS, for modifying diffusion coefficients for poison pins. The method is based on an earlier one which used a one dimensional transport calculation of flux gradient and leakage to determine the effective diffusion coefficient. The improvement is to use a two dimensional characteristics transport calculation to overcome the approximations in geometry made previously. The report explains the theory of the method, describes its use within LWRWIMS, and gives some results obtained. (author)

  18. Determination of axial diffusion coefficients by the Monte-Carlo method

    International Nuclear Information System (INIS)

    Milgram, M.

    1994-01-01

    A simple method to calculate the homogenized diffusion coefficient for a lattice cell using Monte-Carlo techniques is demonstrated. The method relies on modelling a finite reactor volume to induce a curvature in the flux distribution, and then follows a large number of histories to obtain sufficient statistics for a meaningful result. The goal is to determine the diffusion coefficient with sufficient accuracy to test approximate methods built into deterministic lattice codes. Numerical results are given. (author). 4 refs., 8 figs

  19. FIELD-SCALE EFFECTIVE MATRIX DIFFUSION COEFFICIENT FOR FRACTURED ROCK: RESULTS FROM LITERATURE SURVEY

    International Nuclear Information System (INIS)

    Zhou, Q.; Hui-Hai Liu; Molz, F.J.; Zhang, Y.; Bodvarsson, G.S.

    2005-01-01

    Matrix diffusion is an important mechanism for solute transport in fractured rock. We recently conducted a literature survey on the effective matrix diffusion coefficient, D m e , a key parameter for describing matrix diffusion processes at the field scale. Forty field tracer tests at 15 fractured geologic sites were surveyed and selected for the study, based on data availability and quality. Field-scale D m e values were calculated, either directly using data reported in the literature or by reanalyzing the corresponding field tracer tests. Surveyed data indicate that the effective-matrix-diffusion-coefficient factor F D (defined as the ratio of D m e to the lab-scale matrix diffusion coefficient [D m ] of the same tracer) is generally larger than one, indicating that the effective matrix diffusion coefficient in the field is comparatively larger than the matrix diffusion coefficient at the rock-core scale. This larger value can be attributed to the many mass-transfer processes at different scales in naturally heterogeneous, fractured rock systems. Furthermore, we observed a moderate trend toward systematic increase in the F D value with observation scale, indicating that the effective matrix diffusion coefficient is likely to be statistically scale dependent. The F D value ranges from 1 to 10,000 for observation scales from 5 to 2,000 m. At a given scale, the F D value varies by two orders of magnitude, reflecting the influence of differing degrees of fractured rock heterogeneity at different sites. In addition, the surveyed data indicate that field-scale longitudinal dispersivity generally increases with observation scale, which is consistent with previous studies. The scale-dependent field-scale matrix diffusion coefficient (and dispersivity) may have significant implications for assessing long-term, large-scale radionuclide and contaminant transport events in fractured rock, both for nuclear waste disposal and contaminant remediation

  20. Dependence of Exciton Diffusion Length and Diffusion Coefficient on Photophysical Parameters in Bulk Heterojunction Organic Solar Cells

    Science.gov (United States)

    Yeboah, Douglas; Singh, Jai

    2017-11-01

    Recently, the dependence of exciton diffusion length (LD ) on some photophysical parameters of organic solids has been experimentally demonstrated, however no systematic theoretical analysis of this phenomenon has been carried out. We have conducted a theoretical study by using the Förster resonance energy transfer and Dexter carrier transfer mechanisms together with the Einstein-Smoluchowski diffusion equation to derive analytical models for the diffusion lengths (LD ) and diffusion coefficients (D) of singlet (S) and triplet (T) excitons in organic solids as functions of spectral overlap integral (J) , photoluminescence (PL) quantum yield (φD ) , dipole moment (μT ) and refractive index (n) of the photoactive material. The exciton diffusion lengths and diffusion coefficients in some selected organic solids were calculated, and we found that the singlet exciton diffusion length (LDS ) increases with φD and J, and decreases with n. Also, the triplet exciton diffusion length (LDT ) increases with φD and decreases with μT . These may be achieved through doping the organic solids into broad optical energy gap host materials as observed in previous experiments. The calculated exciton diffusion lengths are compared with experimental values and a reasonably good agreement is found between them. The results presented are expected to provide insight relevant to the synthesis of new organic solids for fabrication of bulk heterojunction organic solar cells characterized by better power conversion efficiency.

  1. A nonequilibrium simulation method for calculating tracer diffusion coefficients of small solutes in n-alkane liquids and polymers

    NARCIS (Netherlands)

    van der Vegt, N.F.A.; Briels, Willem J.; Wessling, Matthias; Strathmann, H.

    1998-01-01

    The tracer diffusion coefficients of methane in n-alkane liquids of increasing chain length were calculated by measuring the friction from short time nonequilibrium molecular dynamics simulations. The frictional constant was calculated from the exponentially decaying distance between two methane

  2. Role of apparent diffusion coefficient values and diffusion weighted magnetic resonance imaging in differentiation between benign and malignant thyroid nodules

    International Nuclear Information System (INIS)

    Incedayi, M.; Sivrioglu, A.; Mutlu, H.; Sonmez, G.; Velioglu, M.; Sildiroglu, O.; Basekim, C.; Kizilkaya, E.

    2012-01-01

    Full text: Objective: The purpose of the study was to differentiate between benign and malignant thyroid nodules using nodule-spinal cord signal intensity and nodule apparent diffusion coefficient (ADC) ratios on diffusion weighted magnetic resonance imaging. Materials and methods: Forty-four patients (27 females, 17 males; mean age 49) with nodules who underwent diffusion weighted magnetic resonance imaging (DW-MRI) were included in this study. The images were acquired with 0, 50, 400 and 1000 s/mm 2 b values. ADC maps were calculated afterwards. Fine needle aspiration biopsies (FNAB) were performed at the same day with DW-MRI acquisition. The diagnosis in patients where malignity was detected after FNAB was confirmed by histopathologic analysis of the operation material. The signal intensities of the spinal cord and the nodule were measured additionally, over b-1000 diffusion weighted images. Nodule /cord signal intensity (SI) ratios were obtained and the digital values were calculated by dividing to ADC values estimated for each nodule. Statistical analysis was performed. Results: The (nodule SI-cord SI)/nodule ADC ratio is calculated in the DW images and a statistically significant relationship was found between this ratio and the histopathology of the nodules (p<0.001). The ratio was determined as 0.27 in benign, and 0.86 in malignant lesions. The result of ROC analysis was statistically significant, and the area under Receiver Operating Characteristic (ROC) curve (100%) was considerably high. The threshold value was calculated as 0.56 according to the ROC analysis. According to this threshold value, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy rates for (nodule SI/cord SI)/ADC ratios in differentiating benign from malignant thyroid nodules are calculated as 100%, 97%, 83%, 100%, and 98%, respectively. Conclusion: We have found that (nodule/cord SI)/ nodule ADC ratio has the highest values for

  3. Quantitative differentiation of breast lesions at 3T diffusion-weighted imaging (DWI) using the ratio of distributed diffusion coefficient (DDC).

    Science.gov (United States)

    Ertas, Gokhan; Onaygil, Can; Akin, Yasin; Kaya, Handan; Aribal, Erkin

    2016-12-01

    To investigate the accuracy of diffusion coefficients and diffusion coefficient ratios of breast lesions and of glandular breast tissue from mono- and stretched-exponential models for quantitative diagnosis in diffusion-weighted magnetic resonance imaging (MRI). We analyzed pathologically confirmed 170 lesions (85 benign and 85 malignant) imaged using a 3.0T MR scanner. Small regions of interest (ROIs) focusing on the highest signal intensity for lesions and also for glandular tissue of contralateral breast were obtained. Apparent diffusion coefficient (ADC) and distributed diffusion coefficient (DDC) were estimated by performing nonlinear fittings using mono- and stretched-exponential models, respectively. Coefficient ratios were calculated by dividing the lesion coefficient by the glandular tissue coefficient. A stretched exponential model provides significantly better fits then the monoexponential model (P DDC ratio (area under the curve [AUC] = 0.93) when compared with lesion DDC, ADC ratio, and lesion ADC (AUC = 0.91, 0.90, 0.90) but with no statistically significant difference (P > 0.05). At optimal thresholds, the DDC ratio achieves 93% sensitivity, 80% specificity, and 87% overall diagnostic accuracy, while ADC ratio leads to 89% sensitivity, 78% specificity, and 83% overall diagnostic accuracy. The stretched exponential model fits better with signal intensity measurements from both lesion and glandular tissue ROIs. Although the DDC ratio estimated by using the model shows a higher diagnostic accuracy than the ADC ratio, lesion DDC, and ADC, it is not statistically significant. J. Magn. Reson. Imaging 2016;44:1633-1641. © 2016 International Society for Magnetic Resonance in Medicine.

  4. Optimal Parameters to Determine the Apparent Diffusion Coefficient in Diffusion Weighted Imaging via Simulation

    Science.gov (United States)

    Perera, Dimuthu

    Diffusion weighted (DW) Imaging is a non-invasive MR technique that provides information about the tissue microstructure using the diffusion of water molecules. The diffusion is generally characterized by the apparent diffusion coefficient (ADC) parametric map. The purpose of this study is to investigate in silico how the calculation of ADC is affected by image SNR, b-values, and the true tissue ADC. Also, to provide optimal parameter combination depending on the percentage accuracy and precision for prostate peripheral region cancer application. Moreover, to suggest parameter choices for any type of tissue, while providing the expected accuracy and precision. In this research DW images were generated assuming a mono-exponential signal model at two different b-values and for known true ADC values. Rician noise of different levels was added to the DWI images to adjust the image SNR. Using the two DWI images, ADC was calculated using a mono-exponential model for each set of b-values, SNR, and true ADC. 40,000 ADC data were collected for each parameter setting to determine the mean and the standard-deviation of the calculated ADC, as well as the percentage accuracy and precision with respect to the true ADC. The accuracy was calculated using the difference between known and calculated ADC. The precision was calculated using the standard-deviation of calculated ADC. The optimal parameters for a specific study was determined when both the percentage accuracy and precision were minimized. In our study, we simulated two true ADCs (ADC 0.00102 for tumor and 0.00180 mm2/s for normal prostate peripheral region tissue). Image SNR was varied from 2 to 100 and b-values were varied from 0 to 2000s/mm2. The results show that the percentage accuracy and percentage precision were minimized with image SNR. To increase SNR, 10 signal-averagings (NEX) were used considering the limitation in total scan time. The optimal NEX combination for tumor and normal tissue for prostate

  5. Evaluation of diffusion coefficients from composition profiles - the influence of trapping

    DEFF Research Database (Denmark)

    Christiansen, Thomas; Somers, Marcel A. J.

    2006-01-01

    The applicability of the Boltzmann-Matano method for evaluation of a diffusion coefficient and its concentration dependency by line profile analysis is tested on three different (model) systems. All systems involve interstitial diffusion. It is shown that the occurrence of trapping corrupts...... the applicability of the Boltzmann-Matano method....

  6. Modeling diffusion coefficients in binary mixtures of polar and non-polar compounds

    DEFF Research Database (Denmark)

    Medvedev, Oleg; Shapiro, Alexander

    2005-01-01

    The theory of transport coefficients in liquids, developed previously, is tested on a description of the diffusion coefficients in binary polar/non-polar mixtures, by applying advanced thermodynamic models. Comparison to a large set of experimental data shows good performance of the model. Only f...

  7. A nodal method applied to a diffusion problem with generalized coefficients

    International Nuclear Information System (INIS)

    Laazizi, A.; Guessous, N.

    1999-01-01

    In this paper, we consider second order neutrons diffusion problem with coefficients in L ∞ (Ω). Nodal method of the lowest order is applied to approximate the problem's solution. The approximation uses special basis functions in which the coefficients appear. The rate of convergence obtained is O(h 2 ) in L 2 (Ω), with a free rectangular triangulation. (authors)

  8. Measurement of particle transport coefficients on Alcator C-Mod

    International Nuclear Information System (INIS)

    Luke, T.C.T.

    1994-10-01

    The goal of this thesis was to study the behavior of the plasma transport during the divertor detachment in order to explain the central electron density rise. The measurement of particle transport coefficients requires sophisticated diagnostic tools. A two color interferometer system was developed and installed on Alcator C-Mod to measure the electron density with high spatial (∼ 2 cm) and high temporal (≤ 1.0 ms) resolution. The system consists of 10 CO 2 (10.6 μm) and 4 HeNe (.6328 μm) chords that are used to measure the line integrated density to within 0.08 CO 2 degrees or 2.3 x 10 16 m -2 theoretically. Using the two color interferometer, a series of gas puffing experiments were conducted. The density was varied above and below the threshold density for detachment at a constant magnetic field and plasma current. Using a gas modulation technique, the particle diffusion, D, and the convective velocity, V, were determined. Profiles were inverted using a SVD inversion and the transport coefficients were extracted with a time regression analysis and a transport simulation analysis. Results from each analysis were in good agreement. Measured profiles of the coefficients increased with the radius and the values were consistent with measurements from other experiments. The values exceeded neoclassical predictions by a factor of 10. The profiles also exhibited an inverse dependence with plasma density. The scaling of both attached and detached plasmas agreed well with this inverse scaling. This result and the lack of change in the energy and impurity transport indicate that there was no change in the underlying transport processes after detachment

  9. Measurement of particle transport coefficients on Alcator C-Mod

    Energy Technology Data Exchange (ETDEWEB)

    Luke, T.C.T.

    1994-10-01

    The goal of this thesis was to study the behavior of the plasma transport during the divertor detachment in order to explain the central electron density rise. The measurement of particle transport coefficients requires sophisticated diagnostic tools. A two color interferometer system was developed and installed on Alcator C-Mod to measure the electron density with high spatial ({approx} 2 cm) and high temporal ({le} 1.0 ms) resolution. The system consists of 10 CO{sub 2} (10.6 {mu}m) and 4 HeNe (.6328 {mu}m) chords that are used to measure the line integrated density to within 0.08 CO{sub 2} degrees or 2.3 {times} 10{sup 16}m{sup {minus}2} theoretically. Using the two color interferometer, a series of gas puffing experiments were conducted. The density was varied above and below the threshold density for detachment at a constant magnetic field and plasma current. Using a gas modulation technique, the particle diffusion, D, and the convective velocity, V, were determined. Profiles were inverted using a SVD inversion and the transport coefficients were extracted with a time regression analysis and a transport simulation analysis. Results from each analysis were in good agreement. Measured profiles of the coefficients increased with the radius and the values were consistent with measurements from other experiments. The values exceeded neoclassical predictions by a factor of 10. The profiles also exhibited an inverse dependence with plasma density. The scaling of both attached and detached plasmas agreed well with this inverse scaling. This result and the lack of change in the energy and impurity transport indicate that there was no change in the underlying transport processes after detachment.

  10. Computation of diffusion coefficients for waters of Gauthami Godavari estuary using one-dimensional advection-diffusion model

    Digital Repository Service at National Institute of Oceanography (India)

    Jyothi, D.; Murty, T.V.R.; Sarma, V.V.; Rao, D.P.

    conditions. As the pollutant load on the estuary increases, the. water quality may deteriorate rapidly and therefore the scientific interests are centered on the analysis of water quality. The pollutants will be subjected to a number of physical, chemical... study we have applied one-dimensional advection-diffusion model for the waters of Gauthami Godavari estuary to determine the axial diffusion coefficients and thereby to predict the impact assessment. The study area (Fig. 1) is the lower most 32 km...

  11. Computational error estimates for Monte Carlo finite element approximation with log normal diffusion coefficients

    KAUST Repository

    Sandberg, Mattias

    2015-01-07

    The Monte Carlo (and Multi-level Monte Carlo) finite element method can be used to approximate observables of solutions to diffusion equations with log normal distributed diffusion coefficients, e.g. modelling ground water flow. Typical models use log normal diffusion coefficients with H¨older regularity of order up to 1/2 a.s. This low regularity implies that the high frequency finite element approximation error (i.e. the error from frequencies larger than the mesh frequency) is not negligible and can be larger than the computable low frequency error. This talk will address how the total error can be estimated by the computable error.

  12. Computable error estimates for Monte Carlo finite element approximation of elliptic PDE with lognormal diffusion coefficients

    KAUST Repository

    Hall, Eric

    2016-01-09

    The Monte Carlo (and Multi-level Monte Carlo) finite element method can be used to approximate observables of solutions to diffusion equations with lognormal distributed diffusion coefficients, e.g. modeling ground water flow. Typical models use lognormal diffusion coefficients with H´ older regularity of order up to 1/2 a.s. This low regularity implies that the high frequency finite element approximation error (i.e. the error from frequencies larger than the mesh frequency) is not negligible and can be larger than the computable low frequency error. We address how the total error can be estimated by the computable error.

  13. Apparent diffusion coefficient in glioblastoma with PNET-like components, a GBM variant.

    Science.gov (United States)

    Ali, Saad; Joseph, Nancy M; Perry, Arie; Barajas, Ramon F; Cha, Soonmee

    2014-09-01

    Glioblastoma (GBM) with primitive neuroectodermal tumor (PNET)-like (GBM-PNET) components is a rare variant of GBM. Recent studies describe PNET-like clinical behavior in these patients-with significantly increased propensity for CSF dissemination and a benefit of "PNET-like" chemotherapy. The imaging appearance of GBM-PNET is not well-described and given areas of marked cellularity in the PNET components one might expect significantly reduced diffusion on MRI. The purpose of this study is to quantitatively evaluate the diffusion characteristics in GBM-PNET and compare them with conventional GBMs. Nine patients with surgical specimens yielding GBM-PNET were identified from the UCSF Pathology files. MR images of these patients were reviewed retrospectively. DWI (diffusion-weighted imaging) sequences were analyzed with multiple regions of interests placed within the tumor, and ADC (apparent diffusion coefficient) values were measured. Results were compared to previously published ADC values in pathology-proven conventional GBM cases from our institution. Reduced ADC was seen in GBM-PNET (mean 581 × 10(-6) mm(2)/s, range 338-817) compared to previously published mean of 1,030 × 10(-6) mm(2)/s in the enhancing components of conventional GBMs. We report substantially reduced ADC values in GBM-PNETs compared to conventional GBMs. If demonstrated in a larger sample, when areas of marked reduced diffusion are seen in a suspected GBM, MRI may appropriately direct tissue sampling and can advocate a thorough search for PNET-like components on histopathology. These patients may have a higher chance of developing CSF dissemination and may benefit from "PNET-like" platinum-based chemotherapy.

  14. FORTRAN program for calculating liquid-phase and gas-phase thermal diffusion column coefficients

    International Nuclear Information System (INIS)

    Rutherford, W.M.

    1980-01-01

    A computer program (COLCO) was developed for calculating thermal diffusion column coefficients from theory. The program, which is written in FORTRAN IV, can be used for both liquid-phase and gas-phase thermal diffusion columns. Column coefficients for the gas phase can be based on gas properties calculated from kinetic theory using tables of omega integrals or on tables of compiled physical properties as functions of temperature. Column coefficients for the liquid phase can be based on compiled physical property tables. Program listings, test data, sample output, and users manual are supplied for appendices

  15. Diffusion and solubility coefficients determined by permeation and immersion experiments for organic solvents in HDPE geomembrane.

    Science.gov (United States)

    Chao, Keh-Ping; Wang, Ping; Wang, Ya-Ting

    2007-04-02

    The chemical resistance of eight organic solvents in high density polyethylene (HDPE) geomembrane has been investigated using the ASTM F739 permeation method and the immersion test at different temperatures. The diffusion of the experimental organic solvents in HDPE geomembrane was non-Fickian kinetic, and the solubility coefficients can be consistent with the solubility parameter theory. The diffusion coefficients and solubility coefficients determined by the ASTM F739 method were significantly correlated to the immersion tests (pHDPE as barriers in the field.

  16. Dense fluid self-diffusion coefficient calculations using perturbation theory and molecular dynamics

    Directory of Open Access Journals (Sweden)

    COELHO L. A. F.

    1999-01-01

    Full Text Available A procedure to correlate self-diffusion coefficients in dense fluids by using the perturbation theory (WCA coupled with the smooth-hard-sphere theory is presented and tested against molecular simulations and experimental data. This simple algebraic expression correlates well the self-diffusion coefficients of carbon dioxide, ethane, propane, ethylene, and sulfur hexafluoride. We have also performed canonical ensemble molecular dynamics simulations by using the Hoover-Nosé thermostat and the mean-square displacement formula to compute self-diffusion coefficients for the reference WCA intermolecular potential. The good agreement obtained from both methods, when compared with experimental data, suggests that the smooth-effective-sphere theory is a useful procedure to correlate diffusivity of pure substances.

  17. The surface diffusion coefficient for an arbitrarily curved fluid-fluid interface. (I). General expression

    Science.gov (United States)

    M. C. Sagis, Leonard

    2001-03-01

    In this paper, we develop a theory for the calculation of the surface diffusion coefficient for an arbitrarily curved fluid-fluid interface. The theory is valid for systems in hydrodynamic equilibrium, with zero mass-averaged velocities in the bulk and interfacial regions. We restrict our attention to systems with isotropic bulk phases, and an interfacial region that is isotropic in the plane parallel to the dividing surface. The dividing surface is assumed to be a simple interface, without memory effects or yield stresses. We derive an expression for the surface diffusion coefficient in terms of two parameters of the interfacial region: the coefficient for plane-parallel diffusion D (AB)aa(ξ) , and the driving force d(B)I||(ξ) . This driving force is the parallel component of the driving force for diffusion in the interfacial region. We derive an expression for this driving force using the entropy balance.

  18. Evaluation of satellite derived spectral diffuse attenuation coefficients

    Digital Repository Service at National Institute of Oceanography (India)

    Suresh, T.; Talaulikar, M.; Desa, E.; Mascarenhas, A.A.M.Q.; Matondkar, S.G.P.

    , 443, 490, 510, 555 and 670 nm derived from the ocean color satellite sensor, SeaWiFS with the in-situ measured values from the Arabian Sea is compared. The satellite derived values are found to be comparable to the measured values in the lower...

  19. A new consistent definition of the homogenized diffusion coefficient of a lattice, limitations of the homogenization concept, and discussion of previously defined coefficients

    International Nuclear Information System (INIS)

    Deniz, V.C.

    1980-01-01

    The problem concerned with the correct definition of the homogenized diffusion coefficient of a lattice, and the concurrent problem of whether or not a homogenized diffusion equation can be formally set up, is studied by a space-energy-angle dependent treatment for a general lattice cell using an operator notation which applies to any eigen-problem. A new definition of the diffusion coefficient is given, which combines within itself the individual merits of the two definitions of Benoist. The relation between the new coefficient and the ''uncorrected'' Benoist coefficient is discussed by considering continuous-spectrum and multi-group diffusion equations. Other definitions existing in the literature are briefly discussed. It is concluded that a diffusion coefficient should represent only leakage effects. A comparison is made between the homogenization approach and the approach via eigen-coefficients, and brief indications are given of a possible scheme for the latter. (author)

  20. Diffusion-weighted magnetic resonance imaging of the normal endometrium: temporal and spatial variations of the apparent diffusion coefficient

    International Nuclear Information System (INIS)

    Fornasa, Francesca; Montemezzi, Stefania

    2012-01-01

    Background: Diffusion-weighted magnetic resonance imaging (DWI) is increasingly used in the diagnosis of endometrial disease. No complete knowledge, however, exists yet of the influence of physiology on the endometrial apparent diffusion coefficient (ADC) values on which DWI is based. Purpose: To establish whether the ADC values measured with DWI in the endometrium of healthy reproductive-aged women significantly vary from the early proliferative to the periovulatory phase of the menstrual cycle and between the fundus and the isthmus of the uterus. Material and Methods: In 17 women the endometrial ADC values measured on the fifth menstrual day, both at the fundus and at the isthmus of the uterus, were compared to the values obtained on the 14th day before the subsequent cycle. In 81 women (menstrual day: fifth through 21st) the endometrial ADC values measured at the fundus were compared to the values obtained at the isthmus of the uterus. All examinations were performed with a 1.5 T magnet (b values: 0 and 800 mm/s 2 ). The results were analyzed by means of Student's t-test per paired data. Results: The endometrial ADC values measured on the fifth day of the menstrual cycle were lower than those obtained in the periovulatory phase both at the fundus (mean 0.923 vs. 1.256 x 10 - 3 mm 2 /s) and at the isthmus (mean 1.297 vs. 1.529 x 10 - 3 mm 2 /s) of the uterus. The endometrial ADC values measured at the fundus of the uterus were lower than those obtained at the isthmus (mean 1.132 vs. 1.420 x 10 - 3 mm 2 /s) through the menstrual cycle. All these differences were highly significant (P < 0.001) at statistical analysis. Conclusion: Physiological variations occurring in endometrial ADC values of healthy women should be considered by the radiologists when interpreting DWI examinations in patients with endometrial disease

  1. Research and development of groundwater dating (Part 3). A proposal of determination method for diffusion coefficients of dissolved helium in rock and applicability of estimation of diffusion coefficients using anions

    International Nuclear Information System (INIS)

    Higashihara, Tomohiro; Nakata, Kotaro; Hasegawa, Takuma

    2006-01-01

    Dissolved helium in groundwater is one of the most suitable tracers for the groundwater dating. The diffusion coefficients in aquitard and aquifer were important to estimate an accumulation of the helium in groundwater. However, few papers have been reported about the diffusion of helium in rocks. In this study, effective diffusion coefficients of the helium in sandstones and mudstone were determined using a through-diffusion method. The effective diffusion coefficients of helium were in the range of 1.5 x 10 -10 to 1.1 x 10 -9 m 2 s -1 and larger than those of Br - ions. Geometrical factors for the diffusion of helium were also larger than those for the diffusion of Br - ions. This fact suggests that diffusion path of helium in the rocks is not more restricted than that of Br - ions. The diffusion coefficients of helium were also estimated using the diffusion coefficient of helium in bulk water and formation factors for diffusion of Br - ions. The estimated diffusion coefficients of helium were larger than the effective diffusion coefficients. It is clarified that the effective diffusion coefficients of helium are underestimated by the estimation method using anions. (author)

  2. Apparent diffusion coefficient in cervical cancer of the uterus: comparison with the normal uterine cervix

    International Nuclear Information System (INIS)

    Naganawa, Shinji; Sato, Chiho; Ishigaki, Takeo; Kumada, Hisashi; Miura, Shunichi; Takizawa, Osamu

    2005-01-01

    A relation between apparent diffusion coefficient (ADC) values and tumor cellular density has been reported. The purpose of this study was to measure the ADC values of cervical cancers in the uterus and compare them with those of normal cervical tissues, and to test whether ADC could differentiate between normal and malignant cervical tissues in the uterus. Twelve consecutive female patients with cervical cancer of the uterus and ten female patients with other pelvic abnormalities were included in this study. ADC was measured at 1.5 T with b-factors of 0, 300 and 600 s/mm 2 using single-shot echo-planar diffusion-weighted imaging and a parallel imaging technique. The mean ADC value of cervical cancer lesions was 1.09±0.20 x 10 -3 mm 2 /s, and that of normal cervix tissue was 1.79±0.24 x 10 -3 mm 2 /s (P<0.0001). In nine patients treated by chemotherapy and/or radiation therapy, the mean ADC value of the cervical cancer lesion increased significantly after therapy (P<0.001). The present study showed, with a small number of patients, that ADC measurement has a potential ability to differentiate between normal and cancerous tissue in the uterine cervix. Further study is necessary to determine the accuracy of ADC measurement in monitoring the treatment response. (orig.)

  3. A new consistent definition of the homogenized diffusion coefficient of a lattice, limitations of the homogenization concept, and discussion of previously defined coefficients

    International Nuclear Information System (INIS)

    Deniz, V.C.

    1978-01-01

    The problem concerned with the correct definition of the homogenized diffusion coefficient of a lattice, and the concurrent problem of whether or not a homogenized diffusion equation can be formally set up, is studied by a space-energy angle dependent treatment for a general lattice cell; using an operator notation which applies to any eigen-problem. It is shown that the diffusion coefficient should represent only leakage effects. A new definition of the diffusion coefficient is given, which combines within itself the individual merits of each of the two definitions of Benoist, and reduces to the 'uncorrected' Benoist coefficient in certain cases. The conditions under which a homogenized diffusion equation can be obtained are discussed. A compatison is made between the approach via a diffusion equation and the approach via the eigen-coefficients of Deniz. Previously defined diffusion coefficients are discussed, and it is shown that the transformed eigen-coefficients proposed by Gelbard and by Larsen are unsuitable as diffusion coefficients, and that the cell-edge normalization of the Bonalumi coefficient is not physically justifiable. (author)

  4. Effective scattering coefficient of the cerebral spinal fluid in adult head models for diffuse optical imaging

    Science.gov (United States)

    Custo, Anna; Wells, William M., III; Barnett, Alex H.; Hillman, Elizabeth M. C.; Boas, David A.

    2006-07-01

    An efficient computation of the time-dependent forward solution for photon transport in a head model is a key capability for performing accurate inversion for functional diffuse optical imaging of the brain. The diffusion approximation to photon transport is much faster to simulate than the physically correct radiative transport equation (RTE); however, it is commonly assumed that scattering lengths must be much smaller than all system dimensions and all absorption lengths for the approximation to be accurate. Neither of these conditions is satisfied in the cerebrospinal fluid (CSF). Since line-of-sight distances in the CSF are small, of the order of a few millimeters, we explore the idea that the CSF scattering coefficient may be modeled by any value from zero up to the order of the typical inverse line-of-sight distance, or approximately 0.3 mm-1, without significantly altering the calculated detector signals or the partial path lengths relevant for functional measurements. We demonstrate this in detail by using a Monte Carlo simulation of the RTE in a three-dimensional head model based on clinical magnetic resonance imaging data, with realistic optode geometries. Our findings lead us to expect that the diffusion approximation will be valid even in the presence of the CSF, with consequences for faster solution of the inverse problem.

  5. Modelling of power-reactivity coefficient measurement

    International Nuclear Information System (INIS)

    Strmensky, C.; Petenyi, V.; Jagrik, J.; Minarcin, M.; Hascik, R.; Toth, L.

    2005-01-01

    Report describes results of modeling of power-reactivity coefficient analysis on power-level. In paper we calculate values of discrepancies arisen during transient process. These discrepancies can be arisen as result of experiment evaluation and can be caused by disregard of 3D effects on neutron distribution. The results are critically discussed (Authors)

  6. A numerical study of one-dimensional replicating patterns in reaction-diffusion systems with non-linear diffusion coefficients

    International Nuclear Information System (INIS)

    Ferreri, J. C.; Carmen, A. del

    1998-01-01

    A numerical study of the dynamics of pattern evolution in reaction-diffusion systems is performed, although limited to one spatial dimension. The diffusion coefficients are nonlinear, based on powers of the scalar variables. The system keeps the dynamics of previous studies in the literature, but the presence of nonlinear diffusion generates a field of strong nonlinear interactions due to the presence of receding travelling waves. This field is limited by the plane of symmetry of the space domain and the last born outgoing travelling wave. These effects are discussed. (author). 10 refs., 7 figs

  7. Blackness coefficients, effective diffusion parameters, and control rod worths for thermal reactors - Methods

    Energy Technology Data Exchange (ETDEWEB)

    Bretscher, M M [Argonne National Laboratory, Argonne, IL 60439 (United States)

    1985-07-01

    Simple diffusion theory cannot be used to evaluate control rod worths in thermal neutron reactors because of the strongly absorbing character of the control material. However, reliable control rod worths can be obtained within the framework of diffusion theory if the control material is characterized by a set of mesh-dependent effective diffusion parameters. For thin slab absorbers the effective diffusion parameters can be expressed as functions of a suitably-defined pair of 'blackness coefficients'. Methods for calculating these blackness coefficients in the P1, P3, and P5 approximations, with and without scattering, are presented. For control elements whose geometry does not permit a thin slab treatment, other methods are needed for determining the effective diffusion parameters. One such method, based on reaction rate ratios, is discussed. (author)

  8. Albedo-adjusted fast-neutron diffusion coefficients in reactor reflectors

    International Nuclear Information System (INIS)

    Terney, W.B.

    1975-01-01

    In the newer, larger pressurized-water reactor cores, the calculated power distributions are fairly sensitive to the number of neutron groups used and to the treatment of the reflector cross sections. Comparisons between transport and diffusion calculations show that the latter substantially underpredict the reflector albedos in the fast (top) group and that the power distribution is shifted toward the core center when compared to 4-group transport theory results. When the fast-neutron diffusion coefficients are altered to make the transport- and diffusion-theory albedos agree, the power distributions are also brought into agreement. An expression for the fast-neutron diffusion coefficients in reflector regions has been derived such that the diffusion calculation reproduces the albedo obtained from a transport solution. In addition, a correction factor for mesh effects applicable to coarse mesh problems is presented. The use of the formalism gives the correct albedos and improved power distributions. (U.S.)

  9. Oxygen diffusion coefficient in isolated chicken red and white skeletal muscle fibers in ontogenesis.

    Science.gov (United States)

    Baranov, V I; Belichenko, V M; Shoshenko, C A

    2000-09-01

    Oxygen diffusion from medium to cultured isolated muscle fibers from red gastrocnemius muscle (deep part) (RGM) and white pectoralis muscle (WPM) of embryonic and postnatal chickens (about 6 months) was explored. The intracellular effective O(2) diffusion coefficient (D(i)) in muscle fiber was calculated from a model of a cylindrical fiber with a uniform distribution of an oxygen sink based on these experimentally measured parameters: critical tension of O(2) (PO(2)) on the surface of a fiber, specific rate of O(2) consumption by a weight unit of muscle fibers (;VO(2)), and average diameter of muscle fibers. The results document the rapid hypertrophic growth of RGM fibers when compared to WPM fibers in the second half of the embryonic period and the higher values of;VO(2) and critical PO(2) during the ontogenetic period under study. The oxygen D(i) in RGM fibers of embryos and 1-day chickens was two to three times higher than observed for WPM fibers. For senior chickens, the oxygen D(i) value in RGM and WPM fibers does not differ. The D(i) of O(2) in both RGM and WPM fibers increased from 1.4-2.7 x 10(-8) to 90-95 x 10(-8) cm(2)/s with an ontogenetic increase in fiber diameter from 7. 5 to 67.0 microm. At all stages the oxygen D(i) values in RGM and WPM fibers are significantly lower than the O(2) diffusion coefficient in water: for 11-day embryos they are 889 and 1714 times lower and for adult individuals 25 and 27 times lower, respectively. Why oxygen D(i) values in RGM and WPM fibers are so low and why they are gradually increasing during the course of hypertrophic ontogenetic growth are still unclear. Copyright 2000 Academic Press.

  10. Theory of the diffusion coefficient of neutrons in a lattice containing cavities

    International Nuclear Information System (INIS)

    Benoist, P.

    1964-01-01

    In an previous publication, a simple and general formulation of the diffusion coefficient, which defines the mode of weighting of the mean free paths of the various media, in introducing the collision probabilities in each medium, was established. This expression is demonstrated again here through a more direct method, and the velocity is introduced; new terms are emphasised, the existence of which implies that the representation of the diffusion area as the mean square of the straight line distance from source to absorption is not correct in a lattice. However these terms are of small enough an order of magnitude to he treated as a correction. The general expression also shows the existence, for the radial coefficient, of the series of angular correlation terms, which is seen to converge very slowly for large channels. The term by term computation which was initiated in the first work was then interrupted and a global formulation, which emphasize a resemblance with the problem of the thermal utilisation factor, was adopted. An integral method, analogous to that use for the computation of this factor, gives the possibility to establish new and simple practical formulae, which require the use of a few basic functions only. These formulae are very accurate, as seen from the results of a variational method which was studied as a reference. Various correction effects are reviewed. Expressions which allow the exact treatment of fuel rod clusters are presented. The theory is confronted with various experimental results, and a new method of measuring the radial coefficient is proposed. (author) [fr

  11. Diffusion coefficient of alginate microcapsules used in pancreatic islet transplantation, a method to cure type 1 diabetes

    Science.gov (United States)

    Najdahmadi, Avid; Lakey, Jonathan R. T.; Botvinick, Elliot

    2018-02-01

    Pancreatic islet transplantation is a promising approach of providing insulin in type 1 diabetes. One strategy to protect islets from the host immune system is encapsulation within a porous biocompatible alginate membrane. This encapsulation provides mechanical support to the cells and allows selective diffusion of oxygen, nutrients and insulin while blocking immunoglobulins. These hydrogels form by diffusion of calcium ions into the polymer network and therefore they are highly sensitive to environmental changes and fluctuations in temperature. We investigated the effects of gel concentration, crosslinking time and ambient conditions on material permeability, volume, and rigidity, all of which may change the immunoisolating characteristics of alginate. To measure diffusion coefficient as a method to capture structural changes we studied the diffusion of fluorescently tagged dextrans of different molecular weight into the midplane of alginate microcapsules, the diffusion coefficient is then calculated by fitting observed fluorescence dynamics to the mathematical solution of 1-D diffusion into a sphere. These measurements were performed after incubation in different conditions as well as after an in vivo experiment in six immunocompetent mice for seven days. Additionally, the changes in gel volume after incubation at different temperatures and environmental conditions as well as changes in compression modulus of alginate gels during crosslinking were investigated. Our result show that increase of polymer concentration and crosslinking time leads to a decrease in volume and increase in compression modulus. Furthermore, we found that samples crosslinked and placed in physiological environment, experience an increase in volume. As expected, these volume changes affect diffusion rates of fluorescent dextrans, where volume expansion is correlated with higher calculated diffusion coefficient. This observation is critical to islet protection since higher permeability due

  12. On the Diffusion Coefficient of Two-step Method for LWR analysis

    International Nuclear Information System (INIS)

    Lee, Deokjung; Choi, Sooyoung; Smith, Kord S.

    2015-01-01

    The few-group constants including diffusion coefficients are generated from the assembly calculation results. Once the assembly calculation is done, the cross sections (XSs) are spatially homogenized, and a critical spectrum calculation is performed in order to take into account the neutron leakages of the lattice. The diffusion coefficient is also generated through the critical spectrum calculation. Three different methods of the critical spectrum calculation such as B1 method, P1 method, and fundamental mode (FM) calculation method are considered in this paper. The diffusion coefficients can also be affected by transport approximations for the transport XS calculation which is used in the assembly transport lattice calculation in order to account for the anisotropic scattering effects. The outflow transport approximation and the inflow transport approximation are investigated in this paper. The accuracy of the few group data especially the diffusion coefficients has been studied to optimize the combination of the transport correction methods and the critical spectrum calculation methods using the UNIST lattice physics code STREAM. The combination of the inflow transport approximation and the FM method is shown to provide the highest accuracy in the LWR core calculations. The methodologies to calculate the diffusion coefficients have been reviewed, and the performances of them have been investigated with a LWR core problem. The combination of the inflow transport approximation and the fundamental mode critical spectrum calculation shows the smallest errors in terms of assembly power distribution

  13. Interpretation of diffusion coefficients in nanostructured materials from random walk numerical simulation.

    Science.gov (United States)

    Anta, Juan A; Mora-Seró, Iván; Dittrich, Thomas; Bisquert, Juan

    2008-08-14

    We make use of the numerical simulation random walk (RWNS) method to compute the "jump" diffusion coefficient of electrons in nanostructured materials via mean-square displacement. First, a summary of analytical results is given that relates the diffusion coefficient obtained from RWNS to those in the multiple-trapping (MT) and hopping models. Simulations are performed in a three-dimensional lattice of trap sites with energies distributed according to an exponential distribution and with a step-function distribution centered at the Fermi level. It is observed that once the stationary state is reached, the ensemble of particles follow Fermi-Dirac statistics with a well-defined Fermi level. In this stationary situation the diffusion coefficient obeys the theoretical predictions so that RWNS effectively reproduces the MT model. Mobilities can be also computed when an electrical bias is applied and they are observed to comply with the Einstein relation when compared with steady-state diffusion coefficients. The evolution of the system towards the stationary situation is also studied. When the diffusion coefficients are monitored along simulation time a transition from anomalous to trap-limited transport is observed. The nature of this transition is discussed in terms of the evolution of electron distribution and the Fermi level. All these results will facilitate the use of RW simulation and related methods to interpret steady-state as well as transient experimental techniques.

  14. Perpendicular Diffusion Coefficient of Comic Rays: The Presence of Weak Adiabatic Focusing

    Energy Technology Data Exchange (ETDEWEB)

    Wang, J. F.; Ma, Q. M.; Song, T.; Yuan, S. B. [Research Department of Biomedical Engineering, Institute of Electrical Engineering, Chinese Academy of Science, Beijing 100190 (China); Qin, G., E-mail: wangjunfang@mail.iee.ac.cn, E-mail: qingang@hit.edu.cn [School of Science, Harbin Institute of Technology, Shenzhen 518055 (China)

    2017-08-20

    The influence of adiabatic focusing on particle diffusion is an important topic in astrophysics and plasma physics. In the past, several authors have explored the influence of along-field adiabatic focusing on the parallel diffusion of charged energetic particles. In this paper, using the unified nonlinear transport theory developed by Shalchi and the method of He and Schlickeiser, we derive a new nonlinear perpendicular diffusion coefficient for a non-uniform background magnetic field. This formula demonstrates that the particle perpendicular diffusion coefficient is modified by along-field adiabatic focusing. For isotropic pitch-angle scattering and the weak adiabatic focusing limit, the derived perpendicular diffusion coefficient is independent of the sign of adiabatic focusing characteristic length. For the two-component model, we simplify the perpendicular diffusion coefficient up to the second order of the power series of the adiabatic focusing characteristic quantity. We find that the first-order modifying factor is equal to zero and that the sign of the second order is determined by the energy of the particles.

  15. The Influence of Conditioning Agent on Phosphate Diffusion Coefficient through Polyacrylamide and Agarose Gel

    Directory of Open Access Journals (Sweden)

    Layta Dinira

    2013-03-01

    Full Text Available Excess phosphate in natural water can cause algae grow rapidly, to the extent causing many fish deaths that led to the extinction of certain species. Therefore, an analysis or periodic observations of phosphate levels in the water is needed. The commonly used method is diffusive gradient in thin films (DGT technique. The DGT technique is based on the ability of analyte to diffuse through a gel, which have a value named diffusion coefficient. This research was conducted in order to study the effect of different storage solution to the phosphate diffusion coefficient through polyacrylamide and agarose gels. Initial research performed with making the polyacrylamide and agarose gels. To observe the effect of different storage solutions, the gels partly stored in distilled water gel while the others are stored in a NaCl solution of 0.01 M. Phosphate diffusion coefficient was determined using Fick's Law after analyze the phosphate concentration using UV-Visible spectrophotometer. The results showed that phosphate diffusion coefficient was highest when polyacrylamide and agarose gels stored in NaCl solution of 0.01 M.

  16. Perpendicular Diffusion Coefficient of Comic Rays: The Presence of Weak Adiabatic Focusing

    Science.gov (United States)

    Wang, J. F.; Qin, G.; Ma, Q. M.; Song, T.; Yuan, S. B.

    2017-08-01

    The influence of adiabatic focusing on particle diffusion is an important topic in astrophysics and plasma physics. In the past, several authors have explored the influence of along-field adiabatic focusing on the parallel diffusion of charged energetic particles. In this paper, using the unified nonlinear transport theory developed by Shalchi and the method of He and Schlickeiser, we derive a new nonlinear perpendicular diffusion coefficient for a non-uniform background magnetic field. This formula demonstrates that the particle perpendicular diffusion coefficient is modified by along-field adiabatic focusing. For isotropic pitch-angle scattering and the weak adiabatic focusing limit, the derived perpendicular diffusion coefficient is independent of the sign of adiabatic focusing characteristic length. For the two-component model, we simplify the perpendicular diffusion coefficient up to the second order of the power series of the adiabatic focusing characteristic quantity. We find that the first-order modifying factor is equal to zero and that the sign of the second order is determined by the energy of the particles.

  17. Perpendicular Diffusion Coefficient of Comic Rays: The Presence of Weak Adiabatic Focusing

    International Nuclear Information System (INIS)

    Wang, J. F.; Ma, Q. M.; Song, T.; Yuan, S. B.; Qin, G.

    2017-01-01

    The influence of adiabatic focusing on particle diffusion is an important topic in astrophysics and plasma physics. In the past, several authors have explored the influence of along-field adiabatic focusing on the parallel diffusion of charged energetic particles. In this paper, using the unified nonlinear transport theory developed by Shalchi and the method of He and Schlickeiser, we derive a new nonlinear perpendicular diffusion coefficient for a non-uniform background magnetic field. This formula demonstrates that the particle perpendicular diffusion coefficient is modified by along-field adiabatic focusing. For isotropic pitch-angle scattering and the weak adiabatic focusing limit, the derived perpendicular diffusion coefficient is independent of the sign of adiabatic focusing characteristic length. For the two-component model, we simplify the perpendicular diffusion coefficient up to the second order of the power series of the adiabatic focusing characteristic quantity. We find that the first-order modifying factor is equal to zero and that the sign of the second order is determined by the energy of the particles.

  18. Isotopic mass-dependence of noble gas diffusion coefficients inwater

    Energy Technology Data Exchange (ETDEWEB)

    Bourg, I.C.; Sposito, G.

    2007-06-25

    Noble gas isotopes are used extensively as tracers inhydrologic and paleoclimatic studies. These applications requireknowledge of the isotopic mass (m) dependence of noble gas diffusioncoefficients in water (D), which has not been measured but is estimatedusing experimental D-values for the major isotopes along with an untestedrelationship from kinetic theory, D prop m-0.5. We applied moleculardynamics methods to determine the mass dependence of D for four noblegases at 298 K, finding that D prop m-beta with beta<0.2, whichrefutes the kinetic theory model underlying all currentapplications.

  19. The diffusion coefficient as a function of energy for usual moderators; Le coefficient de diffusion en fonction de l'energie des thermaliseurs usuels

    Energy Technology Data Exchange (ETDEWEB)

    Cadilhac, M; Livolant, M; Pillard, D; Soule, J -L [Commissariat a l' Energie Atomique, Centre d' Etudes Nucleaires de Saclay, 91 - Gif-sur-Yvette (France)

    1966-07-01

    After a review of the definition of the energy function to be taken for the diffusion coefficient used in calculations of reactor cells, in the elementary theory of diffusion, various possible approximations of this function are given. These approximations are shown to be accurate enough for practical uses. Methods for the direct calculations of these approximations for the currently used 'normal' models (methods avoiding the calculation of differential cross sections) are described; these methods are applied to several usual moderators at various temperatures according to different models. (authors) [French] On rappelle la definition de la fonction de l'energie que l'on doit prendre pour le coefficient de diffusion dans les calculs de cellule de reacteur en theorie elementaire de la diffusion. Puis on indique diverses approximations possibles de cette fonction. On montre que ces approximations ont en pratique une precision suffisante. Enfin on decrit des methodes de calcul direct de ces approximations pour les modeles 'normaux' couramment employes (methodes qui evitent d'avoir a calculer les sections efficaces differentielles), et on les applique a plusieurs thermaliseurs usuels a differentes temperatures (selon differents modeles). (auteurs)

  20. Additional Value of Diffusion-Weighted Imaging to Evaluate Prognostic Factors of Breast Cancer: Correlation with the Apparent Diffusion Coefficient

    International Nuclear Information System (INIS)

    Park, Eun Kyung; Cho, Kyu Ran; Seo, Bo Kyoung; Woo, Ok Hee; Cho, Sung Bum; Bae, Jeoung Won

    2016-01-01

    Breast cancer is a heterogeneous disease with diverse prognoses. The main prognostic determinants are lymph node status, tumor size, histological grade, and biological factors, such as hormone receptors, human epidermal growth factor receptor 2 (HER2), Ki-67 protein levels, and p53 expression. Diffusion-weighted imaging (DWI) can be used to measure the apparent diffusion coefficient (ADC) that provides information related to tumor cellularity and the integrity of the cell membranes. The goal of this study was to evaluate whether ADC measurements could provide information on the prognostic factors of breast cancer. A total of 71 women with invasive breast cancer, treated consecutively, who underwent preoperative breast MRIs with DWI at 3.0 Tesla and subsequent surgery, were prospectively included in this study. Each DWI was acquired with b values of 0 and 1000 s/mm 2 . The mean ADC values of the lesions were measured, including the entire lesion on the three largest sections. We performed histopathological analyses for the tumor size, lymph node status, histological grade, hormone receptors, human epidermal growth factor receptor 2 (HER2), Ki-67, p53, and molecular subtypes. The associations with the ADC values and prognostic factors of breast cancer were evaluated using the independent-samples t test and the one-way analysis of variance (ANOVA). A low ADC value was associated with lymph node metastasis (P < 0.01) and with high Ki-67 protein levels (P = 0.03). There were no significant differences in the ADC values among the histological grade (P = 0.48), molecular subtype (P = 0.51), tumor size (P = 0.46), and p53 protein level (P = 0.62). The pre-operative use of the 3.0 Tesla DWI could provide information about the lymph node status and tumor proliferation for breast cancer patients, and could help determine the optimal treatment plan

  1. Determination of the diffusion coefficient of salts in non-Newtonian liquids by the Taylor dispersion method

    Energy Technology Data Exchange (ETDEWEB)

    Mey, Paula; Varges, Priscilla R.; Mendes, Paulo R. de Souza [Dept. of Mechanical Engineering. Pontificia Universidade Catolica do RJ (PUC-Rio), RJ (Brazil)], e-mails: prvarges@puc-rio.br, pmendes@puc-rio.br

    2010-07-01

    This research looked for a method to determine the binary diffusion coefficient D of salts in liquids (especially in drilling fluids) not only accurately, but in a reasonable time. We chose to use the Taylor Dispersion Method. This technique has been used for measuring binary diffusion coefficients in gaseous, liquid and supercritical fluids, due to its simplicity and accuracy. In the method, the diffusion coefficient is determined by the analysis of the dispersion of a pulse of soluble material in a solvent flowing laminarly through a tube. This work describes the theoretical basis and the experimental requirements for the application of the Taylor Dispersion Method, emphasizing the description of our experiment. A mathematical formulation for both Newtonian and non-Newtonian fluids is presented. The relevant sources of errors are discussed. The experimental procedure and associated analysis are validated by applying the method in well known systems, such as NaCl in water.D of salts in liquids (especially in drilling fluids) not only accurately, but in a reasonable time. We chose to use the Taylor Dispersion Method. This technique has been used for measuring binary diffusion coefficients in gaseous, liquid and supercritical fluids, due to its simplicity and accuracy. In the method, the diffusion coefficient is determined by the analysis of the dispersion of a pulse of soluble material in a solvent flowing laminarly through a tube. This work describes the theoretical basis and the experimental requirements for the application of the Taylor Dispersion Method, emphasizing the description of our experiment. A mathematical formulation for both Newtonian and non-Newtonian fluids is presented. The relevant sources of errors are discussed. The experimental procedure and associated analysis are validated by applying the method in well known systems, such as NaCl in water. (author)

  2. Temperature dependent electron transport and rate coefficient studies for e-beam-sustained diffuse gas discharge switching

    International Nuclear Information System (INIS)

    Carter, J.G.; Hunter, S.R.; Christophorou, L.G.

    1987-01-01

    Measurements of the electron drift velocity, w, attachment coefficient, eta/N/sub a/, and ionization coefficient, α/N, have been made in C 2 F 6 /Ar and C 2 F 6 /CH 4 gas mixtures at gas temperatures, T, of 300 and 500 0 K over the concentration range of 0.1 to 100% of the C 2 F 6 . These measurements are useful for modeling the expected behavior of repetitively operated electron-beam sustained diffuse gas discharge opening switches where gas temperatures within the switch are anticipated to rise several hundred degrees during switch operation

  3. Experimental determination of the diffusion coefficient in two-dimensions in ferrous sulphate gels using the finite element method

    International Nuclear Information System (INIS)

    Baldock, C.; Harris, P.J.; Piercy, A.R.; Healy, B.

    2001-01-01

    A novel two-dimensional finite element method for modelling the diffusion which occurs in Fricke or ferrous sulphate type radiation dosimetry gels is presented. In most of the previous work, the diffusion coefficient has been estimated using simple one-dimensional models. This work presents a two-dimensional model which enables the diffusion coefficient to be determined in a much wider range of experimental situations. The model includes the provision for the determination of a drift parameter. To demonstrate the technique comparative diffusion measurements between ferrous sulphate radiation dosimetry gels, with and without xylenol orange chelating agent and carbohydrate additives have been undertaken. Diffusion coefficients of 9.7±0.4, 13.3±0.6 and 9.5±0.8 10-3 cm 2 per h -1 were determined for ferrous sulphate radiation dosimetry gels with and without xylenol orange and with xylenol orange and sucrose additives respectively. Copyright (2001) Australasian College of Physical Scientists and Engineers in Medicine

  4. Regional apparent diffusion coefficient values in 3rd trimester fetal brain

    International Nuclear Information System (INIS)

    Hoffmann, Chen; Weisz, Boaz; Lipitz, Shlomo; Katorza, Eldad; Yaniv, Gal; Bergman, Dafi; Biegon, Anat

    2014-01-01

    Apparent diffusion coefficient (ADC) values in the developing fetus can be used in the diagnosis and prognosis of prenatal brain pathologies. To this end, we measured regional ADC in a relatively large cohort of normal fetal brains in utero. Diffusion-weighted imaging (DWI) was performed in 48 non-sedated 3rd trimester fetuses with normal structural MR imaging results. ADC was measured in white matter (frontal, parietal, temporal, and occipital lobes), basal ganglia, thalamus, pons, and cerebellum. Regional ADC values were compared by one-way ANOVA with gestational age as covariate. Regression analysis was used to examine gestational age-related changes in regional ADC. Four other cases of CMV infection were also examined. Median gestational age was 32 weeks (range, 26-33 weeks). There was a highly significant effect of region on ADC, whereby ADC values were highest in white matter, with significantly lower values in basal ganglia and cerebellum and the lowest values in thalamus and pons. ADC did not significantly change with gestational age in any of the regions tested. In the four cases with fetal CMV infection, ADC value was associated with a global decrease. ADC values in normal fetal brain are relatively stable during the third trimester, show consistent regional variation, and can make an important contribution to the early diagnosis and possibly prognosis of fetal brain pathologies. (orig.)

  5. Regional apparent diffusion coefficient values in 3rd trimester fetal brain

    Energy Technology Data Exchange (ETDEWEB)

    Hoffmann, Chen [Tel Aviv University, Department of Radiology, Sheba Medical Center, Tel Hashomer (affiliated to the Sackler School of Medicine), Tel Aviv (Israel); Sheba Medical Center, Diagnostic Imaging, 52621, Tel Hashomer (Israel); Weisz, Boaz; Lipitz, Shlomo; Katorza, Eldad [Tel Aviv University, Department of Obstetrics and Gynecology, Sheba Medical Center, Tel Hashomer (affiliated to the Sackler School of Medicine), Tel Aviv (Israel); Yaniv, Gal; Bergman, Dafi [Tel Aviv University, Department of Radiology, Sheba Medical Center, Tel Hashomer (affiliated to the Sackler School of Medicine), Tel Aviv (Israel); Biegon, Anat [Stony Brook University School of Medicine, Department of Neurology, Stony Brook, NY (United States)

    2014-07-15

    Apparent diffusion coefficient (ADC) values in the developing fetus can be used in the diagnosis and prognosis of prenatal brain pathologies. To this end, we measured regional ADC in a relatively large cohort of normal fetal brains in utero. Diffusion-weighted imaging (DWI) was performed in 48 non-sedated 3rd trimester fetuses with normal structural MR imaging results. ADC was measured in white matter (frontal, parietal, temporal, and occipital lobes), basal ganglia, thalamus, pons, and cerebellum. Regional ADC values were compared by one-way ANOVA with gestational age as covariate. Regression analysis was used to examine gestational age-related changes in regional ADC. Four other cases of CMV infection were also examined. Median gestational age was 32 weeks (range, 26-33 weeks). There was a highly significant effect of region on ADC, whereby ADC values were highest in white matter, with significantly lower values in basal ganglia and cerebellum and the lowest values in thalamus and pons. ADC did not significantly change with gestational age in any of the regions tested. In the four cases with fetal CMV infection, ADC value was associated with a global decrease. ADC values in normal fetal brain are relatively stable during the third trimester, show consistent regional variation, and can make an important contribution to the early diagnosis and possibly prognosis of fetal brain pathologies. (orig.)

  6. Crack diffusion coefficient - A candidate fracture toughness parameter for short fiber composites

    Science.gov (United States)

    Mull, M. A.; Chudnovsky, A.; Moet, A.

    1987-01-01

    In brittle matrix composites, crack propagation occurs along random trajectories reflecting the heterogeneous nature of the strength field. Considering the crack trajectory as a diffusive process, the 'crack diffusion coefficient' is introduced. From fatigue crack propagation experiments on a set of identical SEN polyester composite specimens, the variance of the crack tip position along the loading axis is found to be a linear function of the effective 'time'. The latter is taken as the effective crack length. The coefficient of proportionality between variance of the crack trajectory and the effective crack length defines the crack diffusion coefficient D which is found in the present study to be 0.165 mm. This parameter reflects the ability of the composite to deviate the crack from the energetically most efficient path and thus links fracture toughness to the microstructure.

  7. New method and installation for rapid determination of radon diffusion coefficient in various materials.

    Science.gov (United States)

    Tsapalov, Andrey; Gulabyants, Loren; Livshits, Mihail; Kovler, Konstantin

    2014-04-01

    The mathematical apparatus and the experimental installation for the rapid determination of radon diffusion coefficient in various materials are developed. The single test lasts not longer than 18 h and allows testing numerous materials, such as gaseous and liquid media, as well as soil, concrete and radon-proof membranes, in which diffusion coefficient of radon may vary in an extremely wide range, from 1·10(-12) to 5·10(-5) m(2)/s. The uncertainty of radon diffusion coefficient estimation depends on the permeability of the sample and varies from about 5% (for the most permeable materials) to 40% (for less permeable materials, such as radon-proof membranes). Copyright © 2014. Published by Elsevier Ltd.

  8. Comparison of apparent diffusion coefficients (ADCs) between two-point and multi-point analyses using high-B-value diffusion MR imaging

    International Nuclear Information System (INIS)

    Kubo, Hitoshi; Maeda, Masayuki; Araki, Akinobu

    2001-01-01

    We evaluated the accuracy of calculating apparent diffusion coefficients (ADCs) using high-B-value diffusion images. Echo planar diffusion-weighted MR images were obtained at 1.5 tesla in five standard locations in six subjects using gradient strengths corresponding to B values from 0 to 3000 s/mm 2 . Estimation of ADCs was made using two methods: a nonlinear regression model using measurements from a full set of B values (multi-point method) and linear estimation using B values of 0 and max only (two-point method). A high correlation between the two methods was noted (r=0.99), and the mean percentage differences were -0.53% and 0.53% in phantom and human brain, respectively. These results suggest there is little error in estimating ADCs calculated by the two-point technique using high-B-value diffusion MR images. (author)

  9. Diffusion-weighted magnetic resonance imaging with apparent diffusion coefficient (ADC) determination in normal and pathological fetal kidneys.

    Science.gov (United States)

    Chaumoitre, K; Colavolpe, N; Shojai, R; Sarran, A; D' Ercole, C; Panuel, M

    2007-01-01

    To assess the use of diffusion-weighted magnetic resonance imaging (DW-MRI) in the evaluation of the fetal kidney and to estimate age-dependent changes in the apparent diffusion coefficient (ADC) of normal and pathological fetal kidneys. DW-MRI was performed on a 1.5-T machine at 23-38 gestational weeks in 51 pregnant women in whom the fetal kidneys were normal and in 10 whose fetuses had renal pathology (three with suspected nephropathy, three with renal tract dilatation, one with unilateral renal venous thrombosis, and three with twin-twin transfusion syndrome (TTTS)). The ADC was measured in an approximately 1-cm2 region of interest within the renal parenchyma. ADC values in normal renal parenchyma ranged from 1.1 to 1.8 10(-3) mm2 s-1. There was no significant age-dependent change in the ADC of normal kidneys. In cases of nephropathy, the ADC value was not always pathological but an ADC map could show abnormal findings. In cases of dilatation, the ADC value was difficult to determine when the dilatation was huge. In cases of TTTS, the ADC of the donor twin was higher than that of the recipient twin and the difference seemed to be related to the severity of the syndrome. Evaluation of the ADC for fetal kidneys is feasible. Fetal measurement of the ADC value and ADC maps may be useful tools with which to explore the fetal kidney when used in conjunction with current methods. DW-MR images, ADC value and ADC map seem to be useful in cases of suspected nephropathy (hyperechoic kidneys), dilated kidney and vascular pathology (renal venous thrombosis, TTTS). Copyright (c) 2006 ISUOG.

  10. Apparent diffusion coefficient histogram analysis of neonatal hypoxic-ischemic encephalopathy

    Energy Technology Data Exchange (ETDEWEB)

    Cauley, Keith A. [University of Massachusetts Medical School, Department of Radiology, Worcester, MA (United States); New York Presbyterian Hospital, Columbia University Medical Center, Department of Radiology, New York, NY (United States); Filippi, Christopher G. [New York Presbyterian Hospital, Columbia University Medical Center, Department of Radiology, New York, NY (United States)

    2014-06-15

    Diffusion-weighted imaging is a valuable tool in the assessment of the neonatal brain, and changes in diffusion are seen in normal development as well as in pathological states such as hypoxic-ischemic encephalopathy (HIE). Various methods of quantitative assessment of diffusion values have been reported. Global ischemic injury occurring during the time of rapid developmental changes in brain myelination can complicate the imaging diagnosis of neonatal HIE. To compare a quantitative method of histographic analysis of brain apparent coefficient (ADC) maps to the qualitative interpretation of routine brain MR imaging studies. We correlate changes in diffusion values with gestational age in radiographically normal neonates, and we investigate the sensitivity of the method as a quantitative measure of hypoxic-ischemic encephalopathy. We reviewed all brain MRI studies from the neonatal intensive care unit (NICU) at our university medical center over a 4-year period to identify cases that were radiographically normal (23 cases) and those with diffuse, global hypoxic-ischemic encephalopathy (12 cases). We histographically displayed ADC values of a single brain slice at the level of the basal ganglia and correlated peak (s-sD{sub av}) and lowest histogram values (s-sD{sub lowest}) with gestational age. Normative s-sD{sub av} values correlated significantly with gestational age and declined linearly through the neonatal period (r {sup 2} = 0.477, P < 0.01). Six of 12 cases of known HIE demonstrated significantly lower s-sD{sub av} and s-sD{sub lowest} ADC values than were reflected in the normative distribution; several cases of HIE fell within a 95% confidence interval for normative studies, and one case demonstrated higher-than-normal s-sD{sub av}. Single-slice histographic display of ADC values is a rapid and clinically feasible method of quantitative analysis of diffusion. In this study normative values derived from consecutive neonates without radiographic evidence of

  11. Diffusion coefficients of rare earth elements in fcc Fe: A first-principles study

    Science.gov (United States)

    Wang, Haiyan; Gao, Xueyun; Ren, Huiping; Chen, Shuming; Yao, Zhaofeng

    2018-01-01

    The diffusion data and corresponding detailed insights are particularly important for the understanding of the related kinetic processes in Fe based alloys, e.g. solute strengthening, phase transition, solution treatment etc. We present a density function theory study of the diffusivity of self and solutes (La, Ce, Y and Nb) in fcc Fe. The five-frequency model was employed to calculate the microscopic parameters in the correlation factors of the solute diffusion. The interactions of the solutes with the first nearest-neighbor vacancy (1nn) are all attractive, and can be well understood on the basis of the combination of the strain-relief effects and the electronic effects. It is found that among the investigated species, Ce is the fastest diffusing solute in fcc Fe matrix followed by Nb, and the diffusion coefficients of these two solutes are about an order of magnitude higher than that of Fe self-diffusion. And the results show that the diffusion coefficient of La is slightly higher than that of Y, and both species are comparable to that of Fe self-diffusion.

  12. Modeling dendrite density from magnetic resonance diffusion measurements

    DEFF Research Database (Denmark)

    Jespersen, Sune Nørhøj; Kroenke, CD; Østergaard, Leif

    2007-01-01

    in this model: (i) the dendrites and axons, which are modeled as long cylinders with two diffusion coefficients, parallel (DL) and perpendicular (DT) to the cylindrical axis, and (ii) an isotropic monoexponential diffusion component describing water diffusion within and across all other structures, i.......e., in extracellular space and glia cells. The model parameters are estimated from 153 diffusion-weighted images acquired from a formalin-fixed baboon brain. A close correspondence between the data and the signal model is found, with the model parameters consistent with literature values. The model provides......Diffusion-weighted imaging (DWI) provides a noninvasive tool to probe tissue microstructure. We propose a simplified model of neural cytoarchitecture intended to capture the essential features important for water diffusion as measured by NMR. Two components contribute to the NMR signal...

  13. Friction Experiments for Dynamical Coefficient Measurement

    Directory of Open Access Journals (Sweden)

    J. J. Arnoux

    2011-01-01

    Full Text Available An experimental study, including three experimental devices, is presented in order to investigate dry friction phenomena in a wide range of sliding speeds for the steel on steel contact. A ballistic setup, with an air gun launch, allows to estimate the friction coefficient between 20 m/s and 80 m/s. Tests are completed by an adaptation of the sensor on a hydraulic tensile machine (0.01 m/s to 3 m/s and a pin-on-disk tribometer mounted on a CNC lathe (1 to 30 m/s. The interactions at the asperity scale are characterized by a white light interferometer surface analysis.

  14. On a new procedure for determining the diffusion coefficients of swarm electrons

    International Nuclear Information System (INIS)

    Winkler, R.; Wilhelm, J.; Braglia, G.L.

    1985-01-01

    A new method for solving the Boltzmann kinetic equation applied to the determination of diffusion coefficients of swarm electrons in a model plasma, and CO 2 and N 2 plasmas is proposed. The method which uses Legendre polynomial expansion of the electron velocity distribution of the stationary and homogeneous plasma, is based upon an analytical isolation of the non-singular part of the general solution from the singular part. The converged values of the diffusion coefficients given by the new method are compared with the results of Monte-Carlo simulations. (D.Gy.)

  15. Estimation of water diffusion coefficient into polycarbonate at different temperatures using numerical simulation

    Energy Technology Data Exchange (ETDEWEB)

    Nasirabadi, P. Shojaee; Jabbari, M.; Hattel, J. H. [Process Modelling Group, Department of Mechanical Engineering, Technical University of Denmark, Nils Koppels Allé, 2800 Kgs. Lyngby (Denmark)

    2016-06-08

    Nowadays, many electronic systems are exposed to harsh conditions of relative humidity and temperature. Mass transport properties of electronic packaging materials are needed in order to investigate the influence of moisture and temperature on reliability of electronic devices. Polycarbonate (PC) is widely used in the electronics industry. Thus, in this work the water diffusion coefficient into PC is investigated. Furthermore, numerical methods used for estimation of the diffusion coefficient and their assumptions are discussed. 1D and 3D numerical solutions are compared and based on this, it is shown how the estimated value can be different depending on the choice of dimensionality in the model.

  16. LETTER TO THE EDITOR: Fractal diffusion coefficient from dynamical zeta functions

    Science.gov (United States)

    Cristadoro, Giampaolo

    2006-03-01

    Dynamical zeta functions provide a powerful method to analyse low-dimensional dynamical systems when the underlying symbolic dynamics is under control. On the other hand, even simple one-dimensional maps can show an intricate structure of the grammar rules that may lead to a non-smooth dependence of global observables on parameters changes. A paradigmatic example is the fractal diffusion coefficient arising in a simple piecewise linear one-dimensional map of the real line. Using the Baladi-Ruelle generalization of the Milnor-Thurnston kneading determinant, we provide the exact dynamical zeta function for such a map and compute the diffusion coefficient from its smallest zero.

  17. Estimating Outer Zone Radial Diffusion Coefficients from Drift Scale Fluctuations in Van Allen Particle Data

    Science.gov (United States)

    O'Brien, T. P., III; Claudepierre, S. G.

    2017-12-01

    During geomagnetic storms, the Earth's outer radiation belt experiences enhanced radial transport. This transport occurs via phase-dependent radial displacements of particles, either by impulsive events or drift resonant waves. Because transport is phase dependent, it produces drift phase bunching, which can be observed with in situ particle detectors. We provide bounds on the radial diffusion coefficients derived from this drift phase structure as seen by NASA's Van Allen Probes. We compare these bounds to published radial diffusion coefficient models, particularly those derived independently from electromagnetic field observations.

  18. Estimation of Water Diffusion Coefficient into Polycarbonate at Different Temperatures Using Numerical Simulation

    DEFF Research Database (Denmark)

    Shojaee Nasirabadi, Parizad; Jabbaribehnam, Mirmasoud; Hattel, Jesper Henri

    2016-01-01

    ) is widely used in the electronics industry. Thus, in this work the water diffusion coefficient into PC is investigated. Furthermore, numerical methods used for estimation of the diffusion coefficient and their assumptions are discussed. 1D and 3D numerical solutions are compared and based on this, itis......Nowadays, many electronic systems are exposed to harsh conditions of relative humidity and temperature. Masstransport properties of electronic packaging materials are needed in order to investigate the influence of moisture andtemperature on reliability of electronic devices. Polycarbonate (PC...... shown how the estimated value can be different depending on the choice of dimensionality in the model....

  19. Determination of Concentration Dependent Diffusion Coefficients of Carbon in Expanded Austenite

    DEFF Research Database (Denmark)

    Hummelshøj, Thomas Strabo; Christiansen, Thomas; Somers, Marcel A. J.

    2008-01-01

    Abstract. In the present paper various experimental procedures to experimentally determine the concentration dependent diffusion coefficient of carbon in expanded austenite are evaluated. To this end thermogravimetric carburization was simulated for various experimental conditions and the evaluated...... composition dependent diffusivity of carbon derived from the simulated experiments was compared with the input data. The most promising procedure for an accurate determination is shown to be stepwise gaseous carburizing of thin foils in a gaseous atmosphere; the finer the stepsize, the more accurate...

  20. Estimating temperature reactivity coefficients by experimental procedures combined with isothermal temperature coefficient measurements and dynamic identification

    International Nuclear Information System (INIS)

    Tsuji, Masashi; Aoki, Yukinori; Shimazu, Yoichiro; Yamasaki, Masatoshi; Hanayama, Yasushi

    2006-01-01

    A method to evaluate the moderator coefficient (MTC) and the Doppler coefficient through experimental procedures performed during reactor physics tests of PWR power plants is proposed. This method combines isothermal temperature coefficient (ITC) measurement experiments and reactor power transient experiments at low power conditions for dynamic identification. In the dynamic identification, either one of temperature coefficients can be determined in such a way that frequency response characteristics of the reactivity change observed by a digital reactivity meter is reproduced from measured data of neutron count rate and the average coolant temperature. The other unknown coefficient can also be determined by subtracting the coefficient obtained from the dynamic identification from ITC. As the proposed method can directly estimate the Doppler coefficient, the applicability of the conventional core design codes to predict the Doppler coefficient can be verified for new types of fuels such as mixed oxide fuels. The digital simulation study was carried out to show the feasibility of the proposed method. The numerical analysis showed that the MTC and the Doppler coefficient can be estimated accurately and even if there are uncertainties in the parameters of the reactor kinetics model, the accuracies of the estimated values are not seriously impaired. (author)

  1. Analysis of ligand-protein exchange by Clustering of Ligand Diffusion Coefficient Pairs (CoLD-CoP)

    Science.gov (United States)

    Snyder, David A.; Chantova, Mihaela; Chaudhry, Saadia

    2015-06-01

    NMR spectroscopy is a powerful tool in describing protein structures and protein activity for pharmaceutical and biochemical development. This study describes a method to determine weak binding ligands in biological systems by using hierarchic diffusion coefficient clustering of multidimensional data obtained with a 400 MHz Bruker NMR. Comparison of DOSY spectrums of ligands of the chemical library in the presence and absence of target proteins show translational diffusion rates for small molecules upon interaction with macromolecules. For weak binders such as compounds found in fragment libraries, changes in diffusion rates upon macromolecular binding are on the order of the precision of DOSY diffusion measurements, and identifying such subtle shifts in diffusion requires careful statistical analysis. The "CoLD-CoP" (Clustering of Ligand Diffusion Coefficient Pairs) method presented here uses SAHN clustering to identify protein-binders in a chemical library or even a not fully characterized metabolite mixture. We will show how DOSY NMR and the "CoLD-CoP" method complement each other in identifying the most suitable candidates for lysozyme and wheat germ acid phosphatase.

  2. Lie Symmetry of the Diffusive Lotka–Volterra System with Time-Dependent Coefficients

    Directory of Open Access Journals (Sweden)

    Vasyl’ Davydovych

    2018-02-01

    Full Text Available Lie symmetry classification of the diffusive Lotka–Volterra system with time-dependent coefficients in the case of a single space variable is studied. A set of such symmetries in an explicit form is constructed. A nontrivial ansatz reducing the Lotka–Volterra system with correctly-specified coefficients to the system of ordinary differential equations (ODEs and an example of the exact solution with a biological interpretation are found.

  3. The use of photon correlation spectroscopy method for determining diffusion coefficient in brine and herring flesh

    Directory of Open Access Journals (Sweden)

    Shumanova M.V.

    2015-03-01

    Full Text Available The process fish salting has been studied by the method of photon correlation spectroscopy; the distribution of salt concentration in the solution and herring flesh with skin has been found, diffusion coefficients and salt concentrations used for creating a mathematical model of the salting technology have been worked out; the possibility of determination by this method the coefficient of dynamic viscosity of solutions and different media (minced meat etc. has been considered

  4. Diffusion coefficient

    Indian Academy of Sciences (India)

    kbhattacharjee

    in bulk water becomes Au. 13 inside cell. Fluorescent Gold Nanocluster Inside a Human Breast Cell. Au. 25. Au. 13. Bulk water. Live cell. Emission energy = E f. / N1/3. Cancer. N = number of Au atoms in cluster ..... <λ/2. Super Resolution Microscopy: < λ/2. STED = Stimulated Emission Depletion (S. HELL). Strategy: two ...

  5. The effect of recombination and attachment on meteor radar diffusion coefficient profiles

    Science.gov (United States)

    Lee, C. S.; Younger, J. P.; Reid, I. M.; Kim, Y. H.; Kim, J.-H.

    2013-04-01

    Estimates of the ambipolar diffusion coefficient producedusing meteor radar echo decay times display an increasing trend below 80-85 km, which is inconsistent with a diffusion-only theory of the evolution of meteor trails. Data from the 33 MHz meteor radar at King Sejong Station, Antarctica, have been compared with observations from the Aura Earth Observing System Microwave Limb Sounder satellite instrument. It has been found that the height at which the diffusion coefficient gradient reverses follows the height of a constant neutral atmospheric density surface. Numerical simulations of meteor trail diffusion including dissociative recombination with atmospheric ions and three-body attachment of free electrons to neutral molecules indicate that three-body attachment is responsible for the distortion of meteor radar diffusion coefficient profiles at heights below 90 km, including the gradient reversal below 80-85 km. Further investigation has revealed that meteor trails with low initial electron line density produce decay times more consistent with a diffusion-only model of meteor trail evolution.

  6. An innovative method for determining the diffusion coefficient of product nuclide

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Chih Lung [Dept. of Nuclear Back-end Management, Taiwan Power Company, Taipei (China); Wang, Tsing Hai [Dept. Biomedical Engineering and Environment Sciences, National Tsing Hua University, Hsinchu (China)

    2017-08-15

    Diffusion is a crucial mechanism that regulates the migration of radioactive nuclides. In this study, an innovative numerical method was developed to simultaneously calculate the diffusion coefficient of both parent and, afterward, series daughter nuclides in a sequentially reactive through-diffusion model. Two constructed scenarios, a serial reaction (RN{sub 1} → RN{sub 2} → RN{sub 3}) and a parallel reaction (RN{sub 1} → RN{sub 2}A + RN{sub 2}B), were proposed and calculated for verification. First, the accuracy of the proposed three-member reaction equations was validated using several default numerical experiments. Second, by applying the validated numerical experimental concentration variation data, the as-determined diffusion coefficient of the product nuclide was observed to be identical to the default data. The results demonstrate the validity of the proposed method. The significance of the proposed numerical method will be particularly powerful in determining the diffusion coefficients of systems with extremely thin specimens, long periods of diffusion time, and parent nuclides with fast decay constants.

  7. Negative Correlation between the Diffusion Coefficient and Transcriptional Activity of the Glucocorticoid Receptor.

    Science.gov (United States)

    Mikuni, Shintaro; Yamamoto, Johtaro; Horio, Takashi; Kinjo, Masataka

    2017-08-25

    The glucocorticoid receptor (GR) is a transcription factor, which interacts with DNA and other cofactors to regulate gene transcription. Binding to other partners in the cell nucleus alters the diffusion properties of GR. Raster image correlation spectroscopy (RICS) was applied to quantitatively characterize the diffusion properties of EGFP labeled human GR (EGFP-hGR) and its mutants in the cell nucleus. RICS is an image correlation technique that evaluates the spatial distribution of the diffusion coefficient as a diffusion map. Interestingly, we observed that the averaged diffusion coefficient of EGFP-hGR strongly and negatively correlated with its transcriptional activities in comparison to that of EGFP-hGR wild type and mutants with various transcriptional activities. This result suggests that the decreasing of the diffusion coefficient of hGR was reflected in the high-affinity binding to DNA. Moreover, the hyper-phosphorylation of hGR can enhance the transcriptional activity by reduction of the interaction between the hGR and the nuclear corepressors.

  8. Determination of Diffusion Coefficients and Activation Energy of Selected Organic Liquids using Reversed-Flow Gas Chromatographic Technique

    International Nuclear Information System (INIS)

    Khalisanni Khalid; Rashid Atta Khan; Sharifuddin Mohd Zain

    2012-01-01

    Evaporation of vaporize organic liquid has ecological consequences when the compounds are introduced into both freshwater and marine environments through industrial effluents, or introduced directly into the air from industrial unit processes such as bioreactors and cooling towers. In such cases, a rapid and simple method are needed to measure physicochemical properties of the organic liquids. The Reversed-Flow Gas Chromatography (RF-GC) sampling technique is an easy, fast and accurate procedure. It was used to measure the diffusion coefficients of vapors from liquid into a carrier gas and at the same time to determine the rate coefficients for the evaporation of the respective liquid. The mathematical expression describing the elution curves of the samples peaks was derived and used to calculate the respective parameters for the selected liquid pollutants selected such as methanol, ethanol, 1-propanol, 1-butanol, n-pentane, n-hexane, n-heptane and n-hexadecane, evaporating into the carrier gas of nitrogen. The values of diffusion coefficients found were compared with those calculated theoretically or reported in the literature. The values of evaporation rate were used to determine the activation energy of respective samples using Arrhenius equation. An interesting finding of this work is by using an alternative mathematical analysis based on equilibrium at the liquid-gas interphase, the comparison leads to profound agreement between theoretical values of diffusion coefficients and experimental evidence. (author)

  9. Determination of the diffusion coefficients of iron and chromium in Pb17Li at 500 deg C

    International Nuclear Information System (INIS)

    Simon, N.; Flament, T.; Terlain, A.

    1992-01-01

    The diffusion of the dissolved metallic species in a liquid metal towards the boundary layer is one of the elementary steps of the overall mass transfer process induced by thermal gradient. This phenomenon is very probably the limiting step in the mass transfer of martensitic Fe-Cr steels in the presence of Pb17Li liquid eutectic alloy. For estimating diffusion flux, the diffusion coefficients of iron and chromium in Pb17Li are needed but are not known. Consequently these data have been determined in CEA laboratory by measuring metal loss of cylindrical specimens after rotation at 500 deg C in Pb17Li for several hours and applying the first Fick diffusion law in the boundary layer whose the thickness has been previously determined by EISENBERG. After a description of the experimental device, the results are presented and discussed

  10. Role of magnetic resonance diffusion imaging and apparent diffusion coefficient values in the evaluation of spinal tuberculosis in Indian patients

    International Nuclear Information System (INIS)

    Palle, Lalitha; Reddy, MCH Balaji; Reddy, K Jagannath

    2010-01-01

    To define a range of apparent diffusion coefficient values in spinal tuberculosis and to evaluate the sensitivity of diffusion-weighted magnetic resonance imaging (DW-MRI) and apparent diffusion coefficient values in patients of spinal tuberculosis. This study was conducted over a period of 20 months and included 110 patients with a total of 230 vertebral bodies. The study was performed in two parts. The first part included all patients of known tuberculosis and patients with classical features of tuberculosis. The second part included patients with spinal pathology of indeterminate etiology. All the patients underwent a routine MRI examination along with diffusion sequences. The apparent diffusion coefficient (ADC) values were calculated from all the involved vertebral bodies. The mean ADC value of affected vertebrae in first part of the study was found to be 1.4 ± 0.20 × 10 −3 mm 2 /s. This ADC value was then applied to patients in the second part of study in order to determine its ability in predicting tuberculosis. This range of ADC values was significantly different from the mean ADC values of normal vertebrae and those with metastatic involvement. However, there was an overlap of ADC values in a few tuberculous vertebrae with the ADC values in metastatic vertebrae. We found that DW-MRI and ADC values may help in the differentiation of spinal tuberculosis from other lesions of similar appearance. However, an overlap of ADC values was noted with those of metastatic vertebrae. Therefore diffusion imaging and ADC values must always be interpreted in association with clinical history and routine MRI findings and not in isolation

  11. The apparent diffusion coefficient of water in gray and white matter of the infant brain

    DEFF Research Database (Denmark)

    Toft, P B; Leth, H; Peitersen, Birgit

    1996-01-01

    PURPOSE: The purpose was to obtain normal values of the apparent diffusion coefficient (ADC) in the infant brain and to compare ADC maps with T1- and T2-weighted images. METHOD: Diffusion was measured in nine infants with an ECG-gated SE sequence compensated for first-order motion. One axial slice...... it appeared on T1- or T2-weighted images. In gray and white matter, the mean ADC ranged from 0.95 x 10(-9) to 1.76 x 10(-9) m2/s. In the frontal and occipital white matter, in the genu corporis callosi, and in the lentiform nucleus, the ADC decreased with increasing age. The cortex/white matter ratio...... of the ADC increased with age and approached 1 at the age of 30 weeks. CONCLUSION: ADC maps add information to the T1 and T2 images about the size and course of unmyelinated as well as myelinated tracts in the immature brain....

  12. Determination of ferrite formation coefficient of tin in an austenitic stainless steel by the diffusion couple method

    International Nuclear Information System (INIS)

    Marchive, Daniel; Treheux, Daniel; Guiraldenq, Pierre

    1976-01-01

    The ferritic action of tin for a 18-10 stainless steel has been measured by two different methods: the first is based on the diffusion couple method and the graphical representation of compositions in a diagram α/α + γ/γ corresponding to ferrite and austenitic elements of the steel. In the second method, ferrite formation is analyzed in small ingots prepared with different chromium and tin concentrations. Ferrite coefficient of tin, compared to chromium is 0.25 with diffusion couples and this value is in good agreement with the classical method [fr

  13. Monte Carlo Finite Volume Element Methods for the Convection-Diffusion Equation with a Random Diffusion Coefficient

    Directory of Open Access Journals (Sweden)

    Qian Zhang

    2014-01-01

    Full Text Available The paper presents a framework for the construction of Monte Carlo finite volume element method (MCFVEM for the convection-diffusion equation with a random diffusion coefficient, which is described as a random field. We first approximate the continuous stochastic field by a finite number of random variables via the Karhunen-Loève expansion and transform the initial stochastic problem into a deterministic one with a parameter in high dimensions. Then we generate independent identically distributed approximations of the solution by sampling the coefficient of the equation and employing finite volume element variational formulation. Finally the Monte Carlo (MC method is used to compute corresponding sample averages. Statistic error is estimated analytically and experimentally. A quasi-Monte Carlo (QMC technique with Sobol sequences is also used to accelerate convergence, and experiments indicate that it can improve the efficiency of the Monte Carlo method.

  14. The diffusion coefficient for 239Pu, 241Am, 99Tc and 137Cs in highly compacted buffer materials

    International Nuclear Information System (INIS)

    Zhou Kanghan; Li Guoding

    1998-01-01

    Based on one-dimension diffusion model, the diffusion coefficients of Pu, Am, Tc and Cs in highly compacted sodium-bentonite generally used as buffer materials in geologic disposal system for high-level radioactive waste have been determined at room temperature in the atmosphere of nitrogen. The results show that the diffusion coefficients of Am, Pu and Tc and about 10 -13 ∼10 -15 m 2 /s, and that of Cs about 10 -12 m 2 /s. The diffusion coefficients of these elements decrease with the increasing of the dry density of buffer materials. From the relationship of diffusion coefficient, retardation coefficient and dry density of bentonite, it has been concluded that Am and Pu transfer predominately by diffusion in solid phase, however, Cs and Tc by diffusion in pore water

  15. Measurement of reactivity coefficients for code validation

    International Nuclear Information System (INIS)

    Nuding, Matthias; Loetsch, Thomas

    2005-01-01

    In the year 2003 measurements in the cold reactor state have been performed at the NPP KKI 2 in order to validate the codes that are used for reactor core calculations and especially for the proof of the shutdown margin that is produced by calculations only. For full power states code verification is quite easy because the calculations can be compared with different measured values, e.g. with the activation values determined by the aeroball system. For cold reactor states, however the data base is smaller, especially for reactor cores that are quite 'inhomogeneous' and have rather high Pu-fiss-and 235 U-contents. At the same time the cold reactor state is important regarding the shutdown margin. For these reasons the measurements mentioned above have been performed in order to check the accuracy of the codes that are used by the operator and by our organization for many years. Basically, boron concentrations and control rod worths for different configurations have been measured. The results of the calculation show a very good agreement with the measured values. Therefore, it can be stated that the operator's as well as our code system is suitable for routine use, e.g. during licensing procedures (Authors)

  16. Trapped-ion anomalous diffusion coefficient on the basis of single mode saturation

    International Nuclear Information System (INIS)

    Koshi, Yuji; Hatayama, Akiyoshi; Ogasawara, Masatada.

    1982-03-01

    Expressions of the anomalous diffusion coefficient due to the dissipative trapped ion instability (DTII) are derived for the case with and without the effect of magnetic shear. Derivation is made by taking into account of the single mode saturation of the DTII previously obtained numerically. In the absence of the shear effect, the diffusion coefficient is proportional to #betta#sub(i)a 2 (#betta#sub(i) is the effective collision frequency of the trapped ions and a is the minor radius of a torus) and is much larger than the neoclassical ion heat conductivity. In the presence of the shear effect, the diffusion coefficient is much smaller than the Kadomtsev and Pogutse's value and is the same order of magnitude as the neoclassical ion heat conductivity. Dependences of the diffusion coefficient on the temperature and on the total particle number density are rather complicated due to the additional spectral cut-off, which is introduced to regularize the short wavelength modes in the numerical analysis. (author)

  17. Calculation of calcium diffusion coefficient of cement hardenings using minute pore data

    International Nuclear Information System (INIS)

    Hitomi, Takashi; Takeda, Nobufumi; Iriya, Keishiro

    2009-01-01

    This report describes the calculations of the diffusion coefficient of the Ca ion of cement hardenings using minute pore data. The observed hardenings were ordinary Portland cement (OPC), low-heat Portland cement with fly ash (LPC+FA) and highly fly ash containing silica fume cement (HFSC). The samples were cured in the standard and artificially leached by accelerated test. Minute pore datas of the cement hardenings were acquired with image processing of internal structural information obtained from high resolution X-ray computed tomography observations. Upon analysis, several voxels are combined into one bigger voxel, the diffusion coefficient of the voxels were determined in proportion to the number of voxels which were included in. The results reveal that the change in the calcium diffusion coefficient of OPC due to leaching was large, but the LPC+FA and HFSC cements exhibited even greater changes than OPC. It is suggested that the diffusion coefficients are proportional to the Ca/Si ratio of the samples. (author)

  18. Diffusion Coefficients in Systems LDPE Plus Cyclohexane and LDPE Plus Benzene

    Czech Academy of Sciences Publication Activity Database

    Randová, A.; Bartovská, L.; Hovorka, Š.; Bartovský, T.; Poloncarzová, Magda; Friess, K.

    -, 068 (2010), s. 1-6 ISSN 1618-7229 R&D Projects: GA ČR GA104/08/0600 Institutional research plan: CEZ:AV0Z40720504 Keywords : swelling * diffusion coefficients * low density polyethylene Subject RIV: CI - Industrial Chemistry, Chemical Engineering Impact factor: 0.574, year: 2010

  19. Computable error estimates for Monte Carlo finite element approximation of elliptic PDE with lognormal diffusion coefficients

    KAUST Repository

    Hall, Eric; Haakon, Hoel; Sandberg, Mattias; Szepessy, Anders; Tempone, Raul

    2016-01-01

    lognormal diffusion coefficients with H´ older regularity of order up to 1/2 a.s. This low regularity implies that the high frequency finite element approximation error (i.e. the error from frequencies larger than the mesh frequency) is not negligible

  20. Computational error estimates for Monte Carlo finite element approximation with log normal diffusion coefficients

    KAUST Repository

    Sandberg, Mattias

    2015-01-01

    log normal diffusion coefficients with H¨older regularity of order up to 1/2 a.s. This low regularity implies that the high frequency finite element approximation error (i.e. the error from frequencies larger than the mesh frequency) is not negligible

  1. Diffusion coefficients for periodically induced multi-step persistent walks on regular lattices

    International Nuclear Information System (INIS)

    Gilbert, Thomas; Sanders, David P

    2012-01-01

    We present a generalization of our formalism for the computation of diffusion coefficients of multi-step persistent random walks on regular lattices to walks which include zero-displacement states. This situation is especially relevant to systems where tracer particles move across potential barriers as a result of the action of a periodic forcing whose period sets the timescale between transitions. (paper)

  2. Unified derivation of the various definitions of lattice cell diffusion coefficients

    International Nuclear Information System (INIS)

    Hughes, R.P.

    1978-01-01

    The various definitions of lattice cell diffusion coefficients are discussed within the context of a one-dimensional slab lattice in one energy group. It is shown how each definition, although originally derived in its own particular way, can be derived from a single approach. This makes clear the differences between, and the advantages of, the various definitions

  3. On conductivity, permittivity, apparent diffusion coefficient, and their usefulness as cancer markers at MRI frequencies.

    Science.gov (United States)

    Hancu, Ileana; Roberts, Jeannette Christine; Bulumulla, Selaka; Lee, Seung-Kyun

    2015-05-01

    To investigate the permittivity and conductivity of cancerous and normal tissues, their correlation to the apparent diffusion coefficient (ADC), and the specificity that they could add to cancer detection. Breast and prostate carcinomas were induced in rats. Conductivity and permittivity measurements were performed in the anesthetized animals using a dielectric probe and an impedance analyzer between 50 and 270 MHz. The correlations between ADCs (measured at 128 MHz) and conductivity values were investigated. Frequency-dependent discriminant functions were computed to assess the value that each parameter adds to cancer detection. Tumors exhibited higher permittivity than muscle tissue by 27%/12%/5% at 64/128/270MHz. Frequency independent, 15-20% higher conductivity was also noted in tumors compared to muscle tissue over the same frequency range. Strong negative correlation was observed between tissue conductivity and ADC. Whereas permittivity had the strongest discriminatory power at 64 MHz, it became comparable to ADC at 128 MHz and less important than ADC at 270 MHz. Conductivity measurements offered limited advantages in separating cancer from normal tissue beyond what ADC already provided; conversely, permittivity added separation power when added to the discriminant function. The moderately high cancerous tissue permittivity and conductivity impose strong constraints on the capability of MRI-based tissue electrical property measurements. © 2014 Wiley Periodicals, Inc.

  4. Accurate determination of the diffusion coefficient of proteins by Fourier analysis with whole column imaging detection.

    Science.gov (United States)

    Zarabadi, Atefeh S; Pawliszyn, Janusz

    2015-02-17

    Analysis in the frequency domain is considered a powerful tool to elicit precise information from spectroscopic signals. In this study, the Fourier transformation technique is employed to determine the diffusion coefficient (D) of a number of proteins in the frequency domain. Analytical approaches are investigated for determination of D from both experimental and data treatment viewpoints. The diffusion process is modeled to calculate diffusion coefficients based on the Fourier transformation solution to Fick's law equation, and its results are compared to time domain results. The simulations characterize optimum spatial and temporal conditions and demonstrate the noise tolerance of the method. The proposed model is validated by its application for the electropherograms from the diffusion path of a set of proteins. Real-time dynamic scanning is conducted to monitor dispersion by employing whole column imaging detection technology in combination with capillary isoelectric focusing (CIEF) and the imaging plug flow (iPF) experiment. These experimental techniques provide different peak shapes, which are utilized to demonstrate the Fourier transformation ability in extracting diffusion coefficients out of irregular shape signals. Experimental results confirmed that the Fourier transformation procedure substantially enhanced the accuracy of the determined values compared to those obtained in the time domain.

  5. measurements of distribution coefficients and lipophilicity values

    African Journals Online (AJOL)

    Preferred Customer

    octanol and water, followed by measuring the distribution of the solute in ... Instrumentation and apparatus: HPLC-UV-DAD and HPLC–ESI-MS experiments .... process in the determination of KD and log P values for the HFSLM extracts. ..... Perrin, D.D.; Dempsey, B. Buffers for pH and Metal Ion Control, Chapman and Hall:.

  6. Calculation of the mutual diffusion coefficient by equilibrium and nonequilibrium molecular dynamics

    International Nuclear Information System (INIS)

    Erpenbeck, J.J.; Kincaid, J.M.

    1985-01-01

    A nonequilibrium molecular dynamics method for the calculation of the mutual diffusion coefficient for a mixture of hard spheres is described. The method is applied to a 50-50 mixture of equidiameter particles having a mass ratio of 0.1 for the two species, at a volume of three times close-packing. By extrapolating the results to the limit of vanishing concentration gradient and infinite system size, we obtain a value in statistical agreement with the result obtained using a Green-Kubo molecular dynamics procedure which is also described. The nonequilibrium calculation yields a mutual diffusion coefficient which decreases slightly with increasing concentration gradient. The Green-Kubo time correlation function for mutual diffusion displays a slow decay with time, qualitatively similar to the long-time tail which has been predicted by the hydrodynamic theory of Pomeau

  7. Calculation of the mutual diffusion coefficient by equilibrium and nonequilibrium molecular dynamics

    International Nuclear Information System (INIS)

    Erpenbeck, J.J.; Kincaid, J.M.

    1986-01-01

    A nonequilibrium molecular dynamics method for the calculation of the mutual diffusion coefficient for a mixture of hard spheres is described. The method is applied to a 50-50 mixture of equidiameter particles having a mass ratio of 0.1 for the two species, at a volume of three times close-packing. By extrapolating the results to the limit of vanishing concentration gradient and infinite system size, we obtain a value in statistical agreement with the result obtained using a Green-Kubo molecular dynamics procedure, which is also described. The nonequilibrium calculation yields a mutual diffusion coefficient which decreases slightly with increasing concentration gradient. The Green-Kubo timecorrelation function for mutual diffusion displays a slow decay with time, qualitatively similar to the long-time tail which has been predicted by the hydrodynamic theory of Pomeau

  8. Determination of uranyl nitrate diffusion coefficients in organic and aqueous media using the porous diaphragm method

    International Nuclear Information System (INIS)

    Chierice, G.O.

    1974-01-01

    The diffusion coefficient is one of the parameters necessary for the obtention of the extraction exponential coefficients, that are contained within the H.T.U. (height of transfer unity) calculation expression, when operating with continuous organic phase. The organic phase used was tri-n-butyl-phosphate (TBP) and varsol in the 35% and 65% proportions respectively. After each experiment, the uranium content present in each compartment was spectrophotometrically determined and the quantities contained in the aqueous phases were determined by means of volumetric titration. It was found out that the uranyl ion diffusion coefficient is two and one half times less in organic phase, this just being attributed to the greater interactions of the uranyl ions in organic than in aqueous medium

  9. Generalized Einstein relation for the mutual diffusion coefficient of a binary fluid mixture.

    Science.gov (United States)

    Felderhof, B U

    2017-08-21

    The method employed by Einstein to derive his famous relation between the diffusion coefficient and the friction coefficient of a Brownian particle is used to derive a generalized Einstein relation for the mutual diffusion coefficient of a binary fluid mixture. The expression is compared with the one derived by de Groot and Mazur from irreversible thermodynamics and later by Batchelor for a Brownian suspension. A different result was derived by several other workers in irreversible thermodynamics. For a nearly incompressible solution, the generalized Einstein relation agrees with the expression derived by de Groot and Mazur. The two expressions also agree to first order in solute density. For a Brownian suspension, the result derived from the generalized Smoluchowski equation agrees with both expressions.

  10. Measurement of conversion coefficients in 208Tl

    International Nuclear Information System (INIS)

    Wendling, F.

    1976-06-01

    A electron spectrometer composed by a Li drifted Si detector and a uniform magnetic field was constructed. The magnetic field is used to focus the electrons on the detector and to filter the other radiations. After the construction the instrument was calibrated in absolute eficience and was used together with a Ge(Li) spectrometer also calibrated, in the measurement of internal conversion coeficients of the 433 and 453 keV transitions in 208 Tl [pt

  11. Calculation and analysis of the mobility and diffusion coefficient of thermal electrons in methane/air premixed flames

    KAUST Repository

    Bisetti, Fabrizio; El Morsli, Mbark

    2012-01-01

    Simulations of ion and electron transport in flames routinely adopt plasma fluid models, which require transport coefficients to compute the mass flux of charged species. In this work, the mobility and diffusion coefficient of thermal electrons

  12. Measuring Restriction Sizes Using Diffusion Weighted Magnetic Resonance Imaging: A Review

    Directory of Open Access Journals (Sweden)

    Melanie Martin

    2013-01-01

    Full Text Available This article reviews a new concept in magnetic resonance as applied to cellular and biological systems. Diffusion weighted magnetic resonance imaging can be used to infer information about restriction sizes of samples being measured. The measurements rely on the apparent diffusion coefficient changing with diffusion times as measurements move from restricted to free diffusion regimes. Pulsed gradient spin echo (PGSE measurements are limited in the ability to shorten diffusion times and thus are limited in restriction sizes which can be probed. Oscillating gradient spin echo (OGSE measurements could provide shorter diffusion times so smaller restriction sizes could be probed.

  13. Determination of diffusion and adsorption coefficients for some contaminants in clayey soil and rock: Laboratory determination and field evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Barone, F S

    1990-01-01

    A laboratory diffusion test determination of diffusion coefficient (D) and adsorption coefficient (K{sub d}) for various inorganic and organic species in a saturated, undisturbed, clayey soil is presented. Diffusion tests conducted for inorganic species (Cl{sup {minus}} , Na{sup +}, K{sup +}, Mg{sup 2+}, and Ca{sup 2+}), involved placing domestic landfill leachate on top of a layer of clay and allowing the chemical constituents to diffuse into the soil. The mathematical model POLLUTE was then used to back-figure (D) and (K{sub d}) for each species. Diffusion tests conducted for organic species (acetone, 1,4-dioxane, aniline, chloroform, and toluene), involved diffusion of the species from a source solution placed on one side of a clay plug, into a distilled water collector solution on the opposite side. Using POLLUTE, D and K{sub d} were then determined by fitting the measured concentration variation with time in both the source and collector solution. In addition to the laboratory study, an investigation of inorganic contaminant diffusion below an existing industrial landfill site was conducted by analyzing soil and pore water specimens from the clay layer underlying the waste. Concentration profiles for Cl{sup {minus}}, So{sub 4}{sup 2{minus}}, Na+, Ca{sup 2+} and Mg{sup 2+}, showed above background levels to a depth of 1.4 m below the waste after 11 years of migration. K{sup +}, B, and NH{sub 3}-N profiles, penetrated to less than 0.5 m below the waste. Field profiles for Na{sup +}, K{sup +}, Cl{sup {minus}}, and SO{sub 4}{sup 2{minus}} were then compared with those predicted using POLLUTE with D and K{sub d} values obtained from diffusion tests using leachate and natural uncontaminated clay from the site. Finally, a laboratory diffusion test determination of Cl{sup {minus}} diffusion coefficient in samples of intact, saturated shale and mudstone is presented.

  14. Diffusion coefficients of the ternary system (2-hydroxypropyl-{beta}-cyclodextrin + caffeine + water) at T = 298.15 K

    Energy Technology Data Exchange (ETDEWEB)

    Ribeiro, Ana C.F. [Department of Chemistry, University of Coimbra, 3004-535 Coimbra (Portugal)], E-mail: anacfrib@ci.uc.pt; Santos, Cecilia I.A.V. [Departamento de Quimica Fisica, Facultad de Farmacia, Universidad de Alcala, 28871 Alcala de Henares, Madrid (Spain)], E-mail: cecilia.alves@uah.es; Lobo, Victor M.M. [Department of Chemistry, University of Coimbra, 3004-535 Coimbra (Portugal)], E-mail: vlobo@ci.uc.pt; Cabral, Ana M.T.D.P.V. [Faculty of Pharmacy, University of Coimbra, 3000-295 Coimbra (Portugal)], E-mail: acabral@ff.uc.pt; Veiga, Francisco J.B. [Faculty of Pharmacy, University of Coimbra, 3000-295 Coimbra (Portugal)], E-mail: fveiga@ci.uc.pt; Esteso, Miguel A. [Departamento de Quimica Fisica, Facultad de Farmacia, Universidad de Alcala, 28871 Alcala de Henares, Madrid (Spain)], E-mail: miguel.esteso@uah.es

    2009-12-15

    Ternary mutual diffusion coefficients measured by Taylor dispersion method (D{sub 11}, D{sub 22}, D{sub 12}, and D{sub 21}) are reported for aqueous solutions of 2-hydroxypropyl-{beta}-cyclodextrin (HP-{beta}-CD) + caffeine at T = 298.15 K at carrier concentrations from (0.000 to 0.010) mol . dm{sup -3}, for each solute, respectively. These diffusion coefficients have been measured having in mind a better understanding of the structure of these systems and thermodynamic behaviour of caffeine and 2-hydroxypropyl-{beta}-cyclodextrin in solution. For example, from these data it will be possible to estimate some parameters, such as the fraction of associated species HP-{beta}-CD (X{sub 1}) and caffeine (X{sub 2}) in this complex, the monomer and dimer fractions, X{sub 2}{sup M} and X{sub 2}{sup D}, respectively, and the limiting diffusion coefficients of the HP-{beta}-CD, D{sub HPBCD}{sup 0}, of the dimers caffeine entities, D{sub D}{sup 0}, and of those complexes (1:1), D{sub complex}{sup 0}.

  15. Diffusion-controlled reaction. V. Effect of concentration-dependent diffusion coefficient on reaction rate in graft polymerization

    International Nuclear Information System (INIS)

    Imre, K.; Odian, G.

    1979-01-01

    The effect of diffusion on radiation-initiated graft polymerization has been studied with emphasis on the single- and two-penetrant cases. When the physical properties of the penetrants are similar, the two-penetrant problems can be reduced to the single-penetrant problem by redefining the characteristic parameters of the system. The diffusion-free graft polymerization rate is assumed to be proportional to the upsilon power of the monomer concentration respectively, and, in which the proportionality constant a = k/sub p/R/sub i//sup w//k/sub t//sup z/, where k/sub p/ and k/sub t/ are the propagation and termination rate constants, respectively, and R/sub i/ is the initiation rate. The values of upsilon, w, and z depend on the particular reaction system. The results of earlier work were generalized by allowing a non-Fickian diffusion rate which predicts an essentially exponential dependence on the monomer concentration of the diffusion coefficient, D = D 0 [exp(deltaC/M)], where M is the saturation concentration. A reaction system is characterized by the three dimensionless parameters, upsilon, delta, and A = (L/2)[aM/sup (upsilon--1)//D 0 ]/sup 1/2/, where L is the polymer film thickness. Graft polymerization tends to become diffusion controlled as A increases. Larger values of delta and ν cause a reaction system to behave closer to the diffusion-free regime. Transition from diffusion-free to diffusion-controlled reaction involves changes in the dependence of the reaction rate on film thickness, initiation rate, and monomer concentration. Although the diffusion-free rate is w order in initiation rate, upsilon order in monomer, and independent of film thickness, the diffusion-controlled rate is w/2 order in initiator rate and inverse first-order in film thickness. Dependence of the diffusion-controlled rate on monomer is dependent in a complex manner on the diffusional characteristics of the reaction system. 11 figures, 4 tables

  16. Diffusion coefficients of alloying elements in dilute Mg alloys: A comprehensive first-principles study

    International Nuclear Information System (INIS)

    Zhou, Bi-Cheng; Shang, Shun-Li; Wang, Yi; Liu, Zi-Kui

    2016-01-01

    First-principles calculations based on density functional theory have been used to calculate the temperature-dependent dilute tracer diffusion coefficients for 47 substitutional alloying elements in hexagonal closed packed (hcp) Mg by combining transition state theory and an 8-frequency model. The minimum energy pathways and the saddle point configurations during solute migration are calculated with the climbing image nudged elastic band method. Vibrational properties are obtained using the quasi-harmonic Debye model with inputs from first-principles calculations. An improved generalized gradient approximation of PBEsol is used in the present first-principles calculations, which is able to well describe both vacancy formation energies and vibrational properties. It is found that the solute diffusion coefficients in hcp Mg are roughly inversely proportional to the bulk modulus of the dilute alloys, which reflects the solutes' bonding to Mg. Transition metal elements with d electrons show strong interactions with Mg and have large diffusion activation energies. Correlation effects are not negligible for solutes Ca, Na, Sr, Se, Te, and Y, in which the direct solute migration barriers are much smaller than the solvent (Mg) migration barriers. Calculated diffusion coefficients are in remarkable agreement with available experimental data in the literature.

  17. Correlation of human papillomavirus status with apparent diffusion coefficient of diffusion-weighted MRI in head and neck squamous cell carcinomas.

    Science.gov (United States)

    Driessen, Juliette P; van Bemmel, Alexander J M; van Kempen, Pauline M W; Janssen, Luuk M; Terhaard, Chris H J; Pameijer, Frank A; Willems, Stefan M; Stegeman, Inge; Grolman, Wilko; Philippens, Marielle E P

    2016-04-01

    Identification of prognostic patient characteristics in head and neck squamous cell carcinoma (HNSCC) is of great importance. Human papillomavirus (HPV)-positive HNSCCs have favorable response to (chemo)radiotherapy. Apparent diffusion coefficient, derived from diffusion-weighted MRI, has also shown to predict treatment response. The purpose of this study was to evaluate the correlation between HPV status and apparent diffusion coefficient. Seventy-three patients with histologically proven HNSCC were retrospectively analyzed. Mean pretreatment apparent diffusion coefficient was calculated by delineation of total tumor volume on diffusion-weighted MRI. HPV status was analyzed and correlated to apparent diffusion coefficient. Six HNSCCs were HPV-positive. HPV-positive HNSCC showed significantly lower apparent diffusion coefficient compared to HPV-negative. This correlation was independent of other patient characteristics. In HNSCC, positive HPV status correlates with low mean apparent diffusion coefficient. The favorable prognostic value of low pretreatment apparent diffusion coefficient might be partially attributed to patients with a positive HPV status. © 2015 Wiley Periodicals, Inc. Head Neck 38: E613-E618, 2016. © 2015 Wiley Periodicals, Inc.

  18. Questionnaire on the measurement condition of distribution coefficient

    International Nuclear Information System (INIS)

    Takebe, Shinichi; Kimura, Hideo; Matsuzuru, Hideo

    2001-05-01

    The distribution coefficient is used for various transport models to evaluate the migration behavior of radionuclides in the environment and is very important parameter in environmental impact assessment of nuclear facility. The questionnaire was carried out for the purpose of utilizing for the proposal of the standard measuring method of distribution coefficient. This report is summarized the result of questionnairing on the sampling methods and storage condition, the pretreatment methods, the analysis items in the physical/chemical characteristics of the sample, and the distribution coefficient measuring method and the measurement conditions in the research institutes within country. (author)

  19. The role of apparent diffusion coefficient in the differentiation between benign and malignant bone tumors

    International Nuclear Information System (INIS)

    Liu Jicun; Cui Jianling; Li Shiling; Guo Zhiping; Ma Xiaohui

    2009-01-01

    Objective: To explore the role of apparent diffusion coefficient (ADC) value of diffusion-weighted imaging (DWI) in the differentiation between benign and malignant bone tumors. Methods: Echo planar imaging DWI was performed in 18 patients with benign tumor or tumorous lesion and 26 patients with malignant tumor of bone. Three b-values (0, 500 and 1000 s/mm 2 ) were applied. The lowest, highest, and whole ADC values were measured for each lesion, respectively. Results: The lowest ADC values of benign bone tumor [mean (1.28 ± 0.49)x10 -3 mm 2 /s] were significantly higher than that of malignant tumor [ mean (0.92 ± 0.35) x10 -3 mm 2 /s,t =2.839,P -3 mm 2 /s] were significantly higher than that of malignant tumor [ mean (1.21 ± 0.36)x10 -3 mm 2 /s, t =3.092, P -3 mm 2 /s] and malignant bone tumor [ mean (1.71 ± 0.65)x10 -3 mm 2 /s, t = 1.669, P > 0.05]. Excluding cases of bone cyst and aneurismal bone cyst, the lowest, highest, and whole ADC values of benign bone tumor waw (1.11 ± 0.31)x10 -3 mm 2 /s, (1.88 ± 0.49)x10 -3 mm 2 /s, and (1.45 ± 0.35)x10 -3 mm 2 /s, respectively. There was no significant difference for the lowest, highest, or whole ADC values between benign and malignant bone tumor (t =1.728, 0.964, and 2.012, respectively, P> 0.05). Conclusion: ADC value is useless for the differentiation between benign and malignant bone tumors. (authors)

  20. Common pediatric cerebellar tumors: correlation between cell densities and apparent diffusion coefficient metrics.

    Science.gov (United States)

    Koral, Korgün; Mathis, Derek; Gimi, Barjor; Gargan, Lynn; Weprin, Bradley; Bowers, Daniel C; Margraf, Linda

    2013-08-01

    To test whether there is correlation between cell densities and apparent diffusion coefficient (ADC) metrics of common pediatric cerebellar tumors. This study was reviewed for issues of patient safety and confidentiality and was approved by the Institutional Review Board of the University of Texas Southwestern Medical Center and was compliant with HIPAA. The need for informed consent was waived. Ninety-five patients who had preoperative magnetic resonance imaging and surgical pathologic findings available between January 2003 and June 2011 were included. There were 37 pilocytic astrocytomas, 34 medulloblastomas (23 classic, eight desmoplastic-nodular, two large cell, one anaplastic), 17 ependymomas (13 World Health Organization [WHO] grade II, four WHO grade III), and seven atypical teratoid rhabdoid tumors. ADCs of solid tumor components and normal cerebellum were measured. Tumor-to-normal brain ADC ratios (hereafter, ADC ratio) were calculated. The medulloblastomas and ependymomas were subcategorized according to the latest WHO classification, and tumor cellularity was calculated. Correlation was sought between cell densities and mean tumor ADCs, minimum tumor ADCs, and ADC ratio. When all tumors were considered together, negative correlation was found between cellularity and mean tumor ADCs (ρ = -0.737, P correlation between cellularity and ADC ratio. Negative correlation was found between cellularity and minimum tumor ADC in atypical teratoid rhabdoid tumors (ρ = -0.786, P correlation was found between cellularity and mean tumor ADC and ADC ratio. There was no correlation between the ADC metrics and cellularity of the pilocytic astrocytomas, medulloblastomas, and ependymomas. Negative correlation was found between cellularity and ADC metrics of common pediatric cerebellar tumors. Although ADC metrics are useful in the preoperative diagnosis of common pediatric cerebellar tumors and this utility is generally attributed to differences in cellularity of tumors

  1. Diffusion coefficients of Fokker-Planck equation for rotating dust grains in a fusion plasma

    Science.gov (United States)

    Bakhtiyari-Ramezani, M.; Mahmoodi, J.; Alinejad, N.

    2015-11-01

    In the fusion devices, ions, H atoms, and H2 molecules collide with dust grains and exert stochastic torques which lead to small variations in angular momentum of the grain. By considering adsorption of the colliding particles, thermal desorption of H atoms and normal H2 molecules, and desorption of the recombined H2 molecules from the surface of an oblate spheroidal grain, we obtain diffusion coefficients of the Fokker-Planck equation for the distribution function of fluctuating angular momentum. Torque coefficients corresponding to the recombination mechanism show that the nonspherical dust grains may rotate with a suprathermal angular velocity.

  2. Diffusion-weighted MRI of epithelial ovarian cancers: Correlation of apparent diffusion coefficient values with histologic grade and surgical stage

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Ji-Won, E-mail: fromentin@naver.com [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Rha, Sung Eun, E-mail: serha@catholic.ac.kr [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Oh, Soon Nam, E-mail: hiohsn@catholic.ac.kr [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Park, Michael Yong, E-mail: digirave@kmle.com [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Byun, Jae Young, E-mail: jybyun@catholic.ac.kr [Department of Radiology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of); Lee, Ahwon, E-mail: klee@catholic.ac.kr [Department of Hospital Pathology, Seoul St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 137-701 (Korea, Republic of)

    2015-04-15

    Highlights: •The solid component of all invasive epithelial cancers showed high b{sub 1000} signal intensity. •ADCs can predict the histologic grade of epithelial ovarian cancer. •ADCs correlate negatively to the surgical stage of epithelial ovarian cancer. •ADCs may be useful imaging biomarkers to assess epithelial ovarian cancer. -- Abstract: Objective: The purpose of this article is to correlate the apparent diffusion coefficient (ADC) values of epithelial ovarian cancers with histologic grade and surgical stage. Materials and methods: We enrolled 43 patients with pathologically proven epithelial ovarian cancers for this retrospective study. All patients underwent preoperative pelvic magnetic resonance imaging (MRI) including diffusion-weighted images with b value of 0 and 1000 s/mm{sup 2} at 3.0-T unit. The mean ADC values of the solid portion of the tumor were measured and compared among different histologic grades and surgical stages. Results: The mean ADC values of epithelial ovarian cancers differed significantly between grade 1 (well-differentiated) and grade 2 (moderately-differentiated) (P = 0.013) as well as between grade 1 and grade 3 (poorly-differentiated) (P = 0.01); however, no statistically significant difference existed between grade 2 and grade 3 (P = 0.737). The receiver-operating characteristic analysis indicated that a cutoff ADC value of less than or equal to 1.09 × 10{sup −3} mm{sup 2}/s was associated with 94.4% sensitivity and 85.7% specificity in distinguishing grade 1 and grade 2/3 cancer. The difference in mean ADC values was statistically significant for early stage (FIGO stage I) and advanced stage (FIGO stage II-IV) cancer (P = 0.011). The interobserver agreement for the mean ADC values of epithelial ovarian cancers was excellent. Conclusion: The mean ADC values of the solid portion of epithelial ovarian cancers negatively correlated to histologic grade and surgical stage. The mean ADC values may be useful imaging

  3. Experimental investigation of the diffusion coefficients in porous media by application of X-ray computer tomography

    DEFF Research Database (Denmark)

    Zhelezny, Petr; Shapiro, Alexander

    2006-01-01

    The present work describes a new experimental method that makes it possible to investigate diffusion coefficients in a porous medium. The method is based on application of X-ray computed tomography (CT). The general applicability of this method for the determination of diffusion coefficients...

  4. Determination of the diffusion coefficient of oxygen in sodium chloride solutions with a transient pulse technique

    NARCIS (Netherlands)

    van Stroe, A.J.; Janssen, L.J.J.

    1993-01-01

    An accurate and rapid method for detg. the diffusion coeffs. of electrochem. active gases in electrolytes is described. The technique is based on chronoamperometry where transient currents are measured and interpreted with a Cottrell-related equation. The diffusion coeffs. of oxygen were detd. for

  5. Molecular dynamics simulation of self-diffusion coefficients for liquid metals

    International Nuclear Information System (INIS)

    Ju Yuan-Yuan; Zhang Qing-Ming; Gong Zi-Zheng; Ji Guang-Fu

    2013-01-01

    The temperature-dependent coefficients of self-diffusion for liquid metals are simulated by molecular dynamics methods based on the embedded-atom-method (EAM) potential function. The simulated results show that a good inverse linear relation exists between the natural logarithm of self-diffusion coefficients and temperature, though the results in the literature vary somewhat, due to the employment of different potential functions. The estimated activation energy of liquid metals obtained by fitting the Arrhenius formula is close to the experimental data. The temperature-dependent shear-viscosities obtained from the Stokes—Einstein relation in conjunction with the results of molecular dynamics simulation are generally consistent with other values in the literature. (atomic and molecular physics)

  6. Quantitative photoacoustic microscopy of optical absorption coefficients from acoustic spectra in the optical diffusive regime.

    Science.gov (United States)

    Guo, Zijian; Favazza, Christopher; Garcia-Uribe, Alejandro; Wang, Lihong V

    2012-06-01

    Photoacoustic (PA) microscopy (PAM) can image optical absorption contrast with ultrasonic spatial resolution in the optical diffusive regime. Conventionally, accurate quantification in PAM requires knowledge of the optical fluence attenuation, acoustic pressure attenuation, and detection bandwidth. We circumvent this requirement by quantifying the optical absorption coefficients from the acoustic spectra of PA signals acquired at multiple optical wavelengths. With the acoustic spectral method, the absorption coefficients of an oxygenated bovine blood phantom at 560, 565, 570, and 575 nm were quantified with errors of <3%. We also quantified the total hemoglobin concentration and hemoglobin oxygen saturation in a live mouse. Compared with the conventional amplitude method, the acoustic spectral method provides greater quantification accuracy in the optical diffusive regime. The limitations of the acoustic spectral method was also discussed.

  7. Shear viscosity and spin-diffusion coefficient of a two-dimensional Fermi gas

    DEFF Research Database (Denmark)

    Bruun, Georg

    2012-01-01

    Using kinetic theory, we calculate the shear viscosity and the spin-diffusion coefficient as well as the associated relaxation times for a two-component Fermi gas in two dimensions, as a function of temperature, coupling strength, polarization, and mass ratio of the two components. It is demonstr......Using kinetic theory, we calculate the shear viscosity and the spin-diffusion coefficient as well as the associated relaxation times for a two-component Fermi gas in two dimensions, as a function of temperature, coupling strength, polarization, and mass ratio of the two components....... It is demonstrated that the minimum value of the viscosity decreases with the mass ratio, since Fermi blocking becomes less efficient. We furthermore analyze recent experimental results for the quadrupole mode of a two-dimensional gas in terms of viscous damping, obtaining a qualitative agreement using no fitting...

  8. Determination of the diffusion coefficient and solubility of radon in plastics.

    Science.gov (United States)

    Pressyanov, D; Georgiev, S; Dimitrova, I; Mitev, K; Boshkova, T

    2011-05-01

    This paper describes a method for determination of the diffusion coefficient and the solubility of radon in plastics. The method is based on the absorption and desorption of radon in plastics. Firstly, plastic specimens are exposed for controlled time to referent (222)Rn concentrations. After exposure, the activity of the specimens is followed by HPGe gamma spectrometry. Using the mathematical algorithm described in this report and the decrease of activity as a function of time, the diffusion coefficient can be determined. In addition, if the referent (222)Rn concentration during the exposure is known, the solubility of radon can be determined. The algorithm has been experimentally applied for different plastics. The results show that this approach allows the specified quantities to be determined with a rather high accuracy-depending on the quality of the counting equipment, it can be better than 10 %.

  9. Flow injection analysis simulations and diffusion coefficient determination by stochastic and deterministic optimization methods.

    Science.gov (United States)

    Kucza, Witold

    2013-07-25

    Stochastic and deterministic simulations of dispersion in cylindrical channels on the Poiseuille flow have been presented. The random walk (stochastic) and the uniform dispersion (deterministic) models have been used for computations of flow injection analysis responses. These methods coupled with the genetic algorithm and the Levenberg-Marquardt optimization methods, respectively, have been applied for determination of diffusion coefficients. The diffusion coefficients of fluorescein sodium, potassium hexacyanoferrate and potassium dichromate have been determined by means of the presented methods and FIA responses that are available in literature. The best-fit results agree with each other and with experimental data thus validating both presented approaches. Copyright © 2013 The Author. Published by Elsevier B.V. All rights reserved.

  10. Determination of the diffusion coefficient of new insulators composed of vegetable fibers

    Directory of Open Access Journals (Sweden)

    Boulaoued I.

    2012-01-01

    Full Text Available The knowledge of the moisture transport of building materials is necessary for the performance of building structures. The control of moisture transport is essential to describe the moisture migration process through the building walls. The present work’s aim is to determine through experiment the water diffusion coefficient of different insulators in unsteady-state based on the Fick’s second law equation. This equation was solved analytically by the separation of variables method (MOD1 and by the change of variables method (MOD2. The moisture diffusion coefficient for building material was experimentally predicted by using the weighing technique and different analytical methods. The results were compared with experimental data.

  11. Determination of the Solute Diffusion Coefficient by the Droplet Migration Method

    Energy Technology Data Exchange (ETDEWEB)

    Shan Liu; Jing Teng; Jeongyun Choi

    2007-07-01

    Further analysis of droplet migration in a temperature gradient field indicates that different terms can be used to evaluate the solute diffusion coefficient in liquid (D{sub L}) and that there exists a characteristic curve that can describe the motion of all the droplets for a given composition and temperature gradient. Critical experiments are subsequently conducted in succinonitrile (SCN)-salol and SCN-camphor transparent alloys in order to observe dynamic migration processes of a number of droplets. The derived diffusion coefficients from different terms are the same within experimental error. For SCN-salol alloys, D{sub L} = (0.69 {+-} 0.05) x 10{sup -3} mm{sup 2}/s, and for SCN-camphor alloys, D{sub L} = (0.24 {+-} 0.02) x 10{sup -3} mm{sup 2}/s.

  12. Role of apparent diffusion coefficients with diffusion-weighted magnetic resonance imaging in differentiating between benign and malignant bone tumors.

    Science.gov (United States)

    Wang, Tingting; Wu, Xiangru; Cui, Yanfen; Chu, Caiting; Ren, Gang; Li, Wenhua

    2014-11-29

    Benign and malignant bone tumors can present similar imaging features. This study aims to evaluate the significance of apparent diffusion coefficients (ADC) in differentiating between benign and malignant bone tumors. A total of 187 patients with 198 bone masses underwent diffusion-weighted (DW) magnetic resonance (MR) imaging. The ADC values in the solid components of the bone masses were assessed. Statistical differences between the mean ADC values in the different tumor types were determined by Student's t-test. Histological analysis showed that 84/198 (42.4%) of the bone masses were benign and 114/198 (57.6%) were malignant. There was a significant difference between the mean ADC values in the benign and malignant bone lesions (Pbenign and malignant bone tumors.

  13. Moisture diffusion coefficients determination of furan bonded sands and water based foundry coatings

    DEFF Research Database (Denmark)

    Di Muoio, Giovanni Luca; Tiedje, Niels Skat

    2016-01-01

    Moisture content in furan bonded sand and water based coatings can be one of the main causes for gas related defects in large cast iron parts. Moisture diffusion coefficients for these materials are needed to precisely predict the possible moisture levels in foundry moulds. In this study, we first...... provide an example on how it is possible to apply this knowledge to estimate moisture variation in a sand mould during production....

  14. Diffusion and the self-measurability

    Directory of Open Access Journals (Sweden)

    Holeček M.

    2009-06-01

    Full Text Available The familiar diffusion equation, ∂g/∂t = DΔg, is studied by using the spatially averaged quantities. A non-local relation, so-called the self-measurability condition, fulfilled by this equation is obtained. We define a broad class of diffusion equations defined by some "diffusion inequality", ∂g/∂t · Δg ≥ 0, and show that it is equivalent to the self-measurability condition. It allows formulating the diffusion inequality in a non-local form. That represents an essential generalization of the diffusion problem in the case when the field g(x, t is not smooth. We derive a general differential equation for averaged quantities coming from the self-measurability condition.

  15. Water and sucrose diffusion coefficients during osmotic dehydration of sapodilla (Achras zapota L.

    Directory of Open Access Journals (Sweden)

    Lívia Muritiba Pereira de Lima Coimbra

    Full Text Available ABSTRACT: Sapodilla is an original fruit from Central America that is well adapted in all regions of the Brazilian territory. Despite its wide adaptation and acceptance in fruit markets, it is rare to find it outside tropical regions, partially because of its high perishability. The development of alternative, simple, and inexpensive methods to extend the conservation and marketing of these fruits is important, and osmotic dehydration is one of these methods. The main objective of this study was to determine the water and sucrose diffusion coefficients during the osmotic dehydration of sapodilla. This process was performed in short duration (up to 6h to evaluate detailed information on water loss and solids gain kinetics at the beginning of the process and in long duration (up to 60h to determine the equilibrium concentrations in sapodilla. The immersion time had greater influence on the water and sucrose diffusion coefficients (P<0.05; the maximum water loss (WL and solute gain (SG occurred in the osmotic solution at the highest concentration. Water and sucrose diffusion coefficients ranged from 0.00 x 10-10 m2/s to 1.858 x 10-10 m2/s, and from 0.00 x 10-10to 2.304 x 10-10 m2/s, respectively. Thus, understanding the WL and SG kinetics during the process of sapodilla osmotic dehydration could significantly contribute to new alternatives of preservation and commercialization of this fruit.

  16. Comparative analyses of diffusion coefficients for different extraction processes from thyme

    Directory of Open Access Journals (Sweden)

    Petrovic Slobodan S.

    2012-01-01

    Full Text Available This work was aimed to analyze kinetics and mass transfer phenomena for different extraction processes from thyme (Thymus vulgaris L. leaves. Different extraction processes with ethanol were studied: Soxhlet extraction and ultrasound-assisted batch extraction on the laboratory scale as well as pilot plant batch extraction with mixing. The extraction processes with ethanol were compared to the process of supercritical carbon dioxide extraction performed at 10 MPa and 40°C. Experimental data were analyzed by mathematical model derived from the Fick’s second law to determine and compare diffusion coefficients in the periods of constant and decreasing extraction rate. In the fast extraction period, values of diffusion coefficients were one to three orders of magnitude higher compared to those determined for the period of slow extraction. The highest diffusion coefficient was reported for the fast extraction period of supercritical fluid extraction. In the case of extraction processes with ethanol, ultrasound, stirring and extraction temperature increase enhanced mass transfer rate in the washing phase. On the other hand, ultrasound contributed the most to the increase of mass transfer rate in the period of slow extraction.

  17. Effect of EDTA and gypsum on self diffusion coefficient of zinc in alkali soil

    International Nuclear Information System (INIS)

    Gupta, G.N.; Deb, D.L.

    1981-01-01

    The effect of EDTA and gypsum application on the rate of zinc diffusion was studied in an alkali soil. Gypsum application at the rate of half gypsum requirement (GR) increased the apparent self diffusion coefficient of zinc (DaZn) and decreased the capacity factor (B) of soil. The higher rates (full GR and double GR) depressed the rate of zinc diffusion and increased the B value. Application of EDTA at the rate of 0.77 μeg -1 of soil produced 1600 and 24 fold increase in DaZn and DpZn values respectively and 100 times drop in B value. Addition of 55 ppm Zn to the soil significantly increased the DaZn and DpZn values. (author)

  18. Mutual diffusion coefficient models for polymer-solvent systems based on the Chapman-Enskog theory

    Directory of Open Access Journals (Sweden)

    R. A. Reis

    2004-12-01

    Full Text Available There are numerous examples of the importance of small molecule migration in polymeric materials, such as in drying polymeric packing, controlled drug delivery, formation of films, and membrane separation, etc. The Chapman-Enskog kinetic theory of hard-sphere fluids with the Weeks-Chandler-Andersen effective hard-sphere diameter (Enskog-WCA has been the most fruitful in diffusion studies of simple fluids and mixtures. In this work, the ability of the Enskog-WCA model to describe the temperature and concentration dependence of the mutual diffusion coefficient, D, for a polystyrene-toluene system was evaluated. Using experimental diffusion data, two polymer model approaches and three mixing rules for the effective hard-sphere diameter were tested. Some procedures tested resulted in models that are capable of correlating the experimental data with the refereed system well for a solvent mass fraction greater than 0.3.

  19. Diffusivity measurements of volatile organics in levitated viscous aerosol particles

    Science.gov (United States)

    Bastelberger, Sandra; Krieger, Ulrich K.; Luo, Beiping; Peter, Thomas

    2017-07-01

    Field measurements indicating that atmospheric secondary organic aerosol (SOA) particles can be present in a highly viscous, glassy state have spurred numerous studies addressing low diffusivities of water in glassy aerosols. The focus of these studies is on kinetic limitations of hygroscopic growth and the plasticizing effect of water. In contrast, much less is known about diffusion limitations of organic molecules and oxidants in viscous matrices. These may affect atmospheric chemistry and gas-particle partitioning of complex mixtures with constituents of different volatility. In this study, we quantify the diffusivity of a volatile organic in a viscous matrix. Evaporation of single particles generated from an aqueous solution of sucrose and small amounts of volatile tetraethylene glycol (PEG-4) is investigated in an electrodynamic balance at controlled relative humidity (RH) and temperature. The evaporative loss of PEG-4 as determined by Mie resonance spectroscopy is used in conjunction with a radially resolved diffusion model to retrieve translational diffusion coefficients of PEG-4. Comparison of the experimentally derived diffusivities with viscosity estimates for the ternary system reveals a breakdown of the Stokes-Einstein relationship, which has often been invoked to infer diffusivity from viscosity. The evaporation of PEG-4 shows pronounced RH and temperature dependencies and is severely depressed for RH ≲ 30 %, corresponding to diffusivities pollutant molecules such as polycyclic aromatic hydrocarbons (PAHs).

  20. Beam diffusion measurements using collimator scans in the LHC

    Directory of Open Access Journals (Sweden)

    Gianluca Valentino

    2013-02-01

    Full Text Available The time evolution of beam losses during a collimator scan provides information on halo diffusion and population. This is an essential input for machine performance characterization and for the design of collimation systems. Beam halo measurements in the CERN Large Hadron Collider were conducted through collimator scrapings in a dedicated beam study for the first time at 4 TeV. Four scans were performed with two collimators, in the vertical plane for beam 1 and horizontally for beam 2, before and after bringing the beams into collisions. Inward and outward steps were performed. A diffusion model was used to interpret the observed loss rate evolution in response to the collimator steps. With this technique, diffusion coefficients were estimated as a function of betatron oscillation amplitude from approximately 3 to 7 standard deviations of the transverse beam distribution. A comparison of halo diffusion and core emittance growth rates is also presented.

  1. Beam diffusion measurements using collimator scans in the LHC

    CERN Document Server

    Valentino, Gianluca; Bruce, Roderik; Burkart, Florian; Previtali, Valentina; Redaelli, Stefano; Salvachua, Belen; Stancari, Giuliov; Valishev, Alexander

    2013-01-01

    The time evolution of beam losses during a collimator scan provides information on halo diffusion and population. This is an essential input for machine performance characterization and for the design of collimation systems. Beam halo measurements in the CERN Large Hadron Collider were conducted through collimator scrapings in a dedicated beam study for the first time at 4 TeV. Four scans were performed with two collimators, in the vertical plane for beam 1 and horizontally for beam 2, before and after bringing the beams into collisions. Inward and outward steps were performed. A diffusion model was used to interpret the observed loss rate evolution in response to the collimator steps. With this technique, diffusion coefficients were estimated as a function of betatron oscillation amplitude from approximately 3 to 7 standard deviations of the transverse beam distribution. A comparison of halo diffusion and core emittance growth rates is also presented.

  2. Determination of 1-octanol-air partition coefficient using gaseous diffusion in the air boundary layer.

    Science.gov (United States)

    Ha, Yeonjeong; Kwon, Jung-Hwan

    2010-04-15

    Exact determination of the partition coefficient between 1-octanol and air (K(OA)) is very important because it is a key descriptor for describing the thermodynamic partitioning between the air and organic phases. In spite of its importance, the number and quality of experimental K(OA) values for hydrophobic organic chemicals are limited because of experimental difficulties. Thus, to measure K(OA) values, a high-throughput method was developed that used liquid-phase extraction with 1-octanol drop at the tip of a microsyringe needle. The concentration in the headspace surrounding the 1 muL octanol drop was equilibrated with liquid octanol containing polycyclic aromatic hydrocarbons (PAHs). The change in concentrations of PAHs in the octanol drop was measured to obtain mass transfer rate constants, and these rate constants were then converted into K(OA) values using a film diffusion model. Thirteen polycyclic aromatic hydrocarbons with log K(OA) between 5 and 12 were chosen for the proof of the principle. Experimental determination of log K(OA) was accomplished in 30 h for PAHs with their log K(OA) less than 11. The measured log K(OA) values were very close to those obtained by various experimental and estimation methods in the literature, suggesting that this new method can provide a fast and easy determination of log K(OA) values for many chemicals of environmental interests. In addition, the applicability of the method can be extended to determine Henry's law constant for compounds with low vapor pressure and to estimate gaseous transfer rate of semivolatile compounds for environmental fate modeling.

  3. A method for estimating the diffuse attenuation coefficient (KdPAR)from paired temperature sensors

    Science.gov (United States)

    Read, Jordan S.; Rose, Kevin C.; Winslow, Luke A.; Read, Emily K.

    2015-01-01

    A new method for estimating the diffuse attenuation coefficient for photosynthetically active radiation (KdPAR) from paired temperature sensors was derived. We show that during cases where the attenuation of penetrating shortwave solar radiation is the dominant source of temperature changes, time series measurements of water temperatures at multiple depths (z1 and z2) are related to one another by a linear scaling factor (a). KdPAR can then be estimated by the simple equation KdPAR ln(a)/(z2/z1). A suggested workflow is presented that outlines procedures for calculating KdPAR according to this paired temperature sensor (PTS) method. This method is best suited for conditions when radiative temperature gains are large relative to physical noise. These conditions occur frequently on water bodies with low wind and/or high KdPARs but can be used for other types of lakes during time periods of low wind and/or where spatially redundant measurements of temperatures are available. The optimal vertical placement of temperature sensors according to a priori knowledge of KdPAR is also described. This information can be used to inform the design of future sensor deployments using the PTS method or for campaigns where characterizing sub-daily changes in temperatures is important. The PTS method provides a novel method to characterize light attenuation in aquatic ecosystems without expensive radiometric equipment or the user subjectivity inherent in Secchi depth measurements. This method also can enable the estimation of KdPAR at higher frequencies than many manual monitoring programs allow.

  4. Diffusion-weighted magnetic resonance imaging in the characterization of testicular germ cell neoplasms: Effect of ROI methods on apparent diffusion coefficient values and interobserver variability

    Energy Technology Data Exchange (ETDEWEB)

    Tsili, Athina C., E-mail: a_tsili@yahoo.gr [Department of Clinical Radiology, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece); Ntorkou, Alexandra, E-mail: alexdorkou@hotmail.com [Department of Clinical Radiology, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece); Astrakas, Loukas, E-mail: astrakas@uoi.gr [Department of Medical Physics, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece); Xydis, Vasilis, E-mail: vxydis@cc.uoi.gr [Department of Clinical Radiology, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece); Tsampalas, Stavros, E-mail: stamp@gmail.com [Department of Urology, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece); Sofikitis, Nikolaos, E-mail: akrosnin@hotmail.com [Department of Urology, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece); Argyropoulou, Maria I., E-mail: margyrop@cc.uoi.gr [Department of Clinical Radiology, Medical School, University of Ioannina, University Campus, 45110, Ioannina (Greece)

    2017-04-15

    Highlights: • Seminomas have lower mean ADC compared to NSGCNs. • Round ROI is accurate in characterizing TGCNS. • ROI shape has no significant effect on interobserver variability. - Abstract: Introduction: To evaluate the difference in apparent diffusion coefficient (ADC) measurements at diffusion-weighted (DW) magnetic resonance imaging of differently shaped regions-of-interest (ROIs) in testicular germ cell neoplasms (TGCNS), the diagnostic ability of differently shaped ROIs in differentiating seminomas from nonseminomatous germ cell neoplasms (NSGCNs) and the interobserver variability. Materials and methods: Thirty-three TGCNs were retrospectively evaluated. Patients underwent MR examinations, including DWI on a 1.5-T MR system. Two observers measured mean tumor ADCs using four distinct ROI methods: round, square, freehand and multiple small, round ROIs. The interclass correlation coefficient was analyzed to assess interobserver variability. Statistical analysis was used to compare mean ADC measurements among observers, methods and histologic types. Results: All ROI methods showed excellent interobserver agreement, with excellent correlation (P < 0.001). Multiple, small ROIs provided the lower mean ADC in TGCNs. Seminomas had lower mean ADC compared to NSGCNs for each ROI method (P < 0.001). Round ROI proved the most accurate method in characterizing TGCNS. Conclusion: Interobserver variability in ADC measurement is excellent, irrespective of the ROI shape. Multiple, small round ROIs and round ROI proved the more accurate methods for ADC measurement in the characterization of TGCNs and in the differentiation between seminomas and NSGCNs, respectively.

  5. Measuring Charge Carrier Diffusion in Coupled Colloidal Quantum Dot Solids

    KAUST Repository

    Zhitomirsky, David

    2013-06-25

    Colloidal quantum dots (CQDs) are attractive materials for inexpensive, room-temperature-, and solution-processed optoelectronic devices. A high carrier diffusion length is desirable for many CQD device applications. In this work we develop two new experimental methods to investigate charge carrier diffusion in coupled CQD solids under charge-neutral, i.e., undepleted, conditions. The methods take advantage of the quantum-size-effect tunability of our materials, utilizing a smaller-bandgap population of quantum dots as a reporter system. We develop analytical models of diffusion in 1D and 3D structures that allow direct extraction of diffusion length from convenient parametric plots and purely optical measurements. We measure several CQD solids fabricated using a number of distinct methods and having significantly different doping and surface ligand treatments. We find that CQD materials recently reported to achieve a certified power conversion efficiency of 7% with hybrid organic-inorganic passivation have a diffusion length of 80 ± 10 nm. The model further allows us to extract the lifetime, trap density, mobility, and diffusion coefficient independently in each material system. This work will facilitate further progress in extending the diffusion length, ultimately leading to high-quality CQD solid semiconducting materials and improved CQD optoelectronic devices, including CQD solar cells. © 2013 American Chemical Society.

  6. Carrier illumination measurement of dopant lateral diffusion

    International Nuclear Information System (INIS)

    Budiarto, E.; Segovia, M.; Borden, P.; Felch, S.

    2005-01-01

    This paper describes the application of the carrier illumination technique to non-destructively measure the lateral diffusion of implanted dopants after annealing. Experiments to validate the feasibility of this method employed test structures with a constant line width of 300 nm and varying undoped spaces of 100-5000 nm. The test patterns were implanted with a p-type dopant and annealed in a 3 x 3 matrix. For each implant condition, the measured lateral diffusion was found to increase with annealing temperature, as expected. More interestingly, the lateral diffusion was not observed to relate to the vertical diffusion by a fixed proportionality factor, as is usually assumed. The ratio of lateral to vertical diffusion varies with annealing temperature, with a trend that depends on the implant condition

  7. Measurement of heat transfer coefficient using termoanemometry methods

    Science.gov (United States)

    Dančová, P.; Sitek, P.; Vít, T.

    2014-03-01

    This work deals with a measurement of heat transfer from a heated flat plate on which a synthetic jet impacts perpendicularly. Measurement of a heat transfer coefficient (HTC) is carried out using the hot wire anemometry method with glue film probe Dantec 55M47. The paper brings also results of velocity profiles measurements and turbulence intensity calculations.

  8. Measurement of heat transfer coefficient using termoanemometry methods

    Directory of Open Access Journals (Sweden)

    Dančová P.

    2014-03-01

    Full Text Available This work deals with a measurement of heat transfer from a heated flat plate on which a synthetic jet impacts perpendicularly. Measurement of a heat transfer coefficient (HTC is carried out using the hot wire anemometry method with glue film probe Dantec 55M47. The paper brings also results of velocity profiles measurements and turbulence intensity calculations.

  9. Measurement and analysis of reactivity temperature coefficient of CEFR

    International Nuclear Information System (INIS)

    Chen Yiyu; Hu Yun; Yang Xiaoyan; Fan Zhendong; Zhang Qiang; Zhao Jinkun; Li Zehua

    2013-01-01

    The reactivity temperature coefficient of CEFR was calculated by CITATION program and compared with the results calculated by correlative programs and measured from experiments for temperature effects. It is indicated that the calculation results from CITATION agree well with measured values. The reactivity temperature coefficient of CEFR is about -4 pcm/℃. The deviation of the measured values between the temperature increasing and decreasing processes is about 11%, which satisfies the experiment acceptance criteria. The measured results can validate the calculation ones by program and can provide important reference data for the safety operation of CEFR and the analysis of the reactivity balance in the reactor refueling situation. (authors)

  10. Measurement of Dynamic Friction Coefficient on the Irregular Free Surface

    International Nuclear Information System (INIS)

    Yeom, S. H.; Seo, K. S.; Lee, J. H.; Lee, K. H.

    2007-01-01

    A spent fuel storage cask must be estimated for a structural integrity when an earthquake occurs because it freely stands on ground surface without a restriction condition. Usually the integrity estimation for a seismic load is performed by a FEM analysis, the friction coefficient for a standing surface is an important parameter in seismic analysis when a sliding happens. When a storage cask is placed on an irregular ground surface, measuring a friction coefficient of an irregular surface is very difficult because the friction coefficient is affected by the surface condition. In this research, dynamic friction coefficients on the irregular surfaces between a concrete cylinder block and a flat concrete slab are measured with two methods by one direction actuator

  11. Apparent diffusion coefficient of breast cancer and normal fibroglandular tissue in diffusion-weighted imaging: the effects of menstrual cycle and menopausal status.

    Science.gov (United States)

    Kim, Jin You; Suh, Hie Bum; Kang, Hyun Jung; Shin, Jong Ki; Choo, Ki Seok; Nam, Kyung Jin; Lee, Seok Won; Jung, Young Lae; Bae, Young Tae

    2016-05-01

    The purpose of this study was to investigate prospectively whether the apparent diffusion coefficients (ADCs) of both breast cancer and normal fibroglandular tissue vary with the menstrual cycle and menopausal status. Institutional review board approval was obtained, and informed consent was obtained from each participant. Fifty-seven women (29 premenopausal, 28 postmenopausal) with newly diagnosed breast cancer underwent diffusion-weighted imaging twice (interval 12-20 days) before surgery. Two radiologists independently measured ADC of breast cancer and normal contralateral breast tissue, and we quantified the differences according to the phases of menstrual cycle and menopausal status. With normal fibroglandular tissue, ADC was significantly lower in postmenopausal than in premenopausal women (P = 0.035). In premenopausal women, ADC did not differ significantly between proliferative and secretory phases in either breast cancer or normal fibroglandular tissue (P = 0.969 and P = 0.519, respectively). In postmenopausal women, no significant differences were found between ADCs measured at different time intervals in either breast cancer or normal fibroglandular tissue (P = 0.948 and P = 0.961, respectively). The within-subject variability of the ADC measurements was quantified using the coefficient of variation (CV) and was small: the mean CVs of tumor ADC were 2.90 % (premenopausal) and 3.43 % (postmenopausal), and those of fibroglandular tissue ADC were 4.37 % (premenopausal) and 2.55 % (postmenopausal). Both intra- and interobserver agreements were excellent for ADC measurements, with intraclass correlation coefficients in the range of 0.834-0.974. In conclusion, the measured ADCs of breast cancer and normal fibroglandular tissue were not affected significantly by menstrual cycle, and the measurements were highly reproducible both within and between observers.

  12. Determination of Krypton Diffusion Coefficients in Uranium Dioxide Using Atomic Scale Calculations.

    Science.gov (United States)

    Vathonne, Emerson; Andersson, David A; Freyss, Michel; Perriot, Romain; Cooper, Michael W D; Stanek, Christopher R; Bertolus, Marjorie

    2017-01-03

    We present a study of the diffusion of krypton in UO 2 using atomic scale calculations combined with diffusion models adapted to the system studied. The migration barriers of the elementary mechanisms for interstitial or vacancy assisted migration are calculated in the DFT+U framework using the nudged elastic band method. The attempt frequencies are obtained from the phonon modes of the defect at the initial and saddle points using empirical potential methods. The diffusion coefficients of Kr in UO 2 are then calculated by combining this data with diffusion models accounting for the concentration of vacancies and the interaction of vacancies with Kr atoms. We determined the preferred mechanism for Kr migration and the corresponding diffusion coefficient as a function of the oxygen chemical potential μ O or nonstoichiometry. For very hypostoichiometric (or U-rich) conditions, the most favorable mechanism is interstitial migration. For hypostoichiometric UO 2 , migration is assisted by the bound Schottky defect and the charged uranium vacancy, V U 4- . Around stoichiometry, migration assisted by the charged uranium-oxygen divacancy (V UO 2- ) and V U 4- is the favored mechanism. Finally, for hyperstoichiometric or O-rich conditions, the migration assisted by two V U 4- dominates. Kr migration is enhanced at higher μ O , and in this regime, the activation energy will be between 4.09 and 0.73 eV depending on nonstoichiometry. The experimental values available are in the latter interval. Since it is very probable that these values were obtained for at least slightly hyperstoichiometric samples, our activation energies are consistent with the experimental data, even if further experiments with precisely controlled stoichiometry are needed to confirm these results. The mechanisms and trends with nonstoichiometry established for Kr are similar to those found in previous studies of Xe.

  13. Non intrusive measurement of the convective heat transfer coefficient

    Energy Technology Data Exchange (ETDEWEB)

    Rebay, M.; Mebarki, G.; Padet, J. [Reims Univ., Reims (France). Faculty of Science, GRESPI Thermomechanical Lab; Arfaoui, A. [Reims Univ., Reims (France). Faculty of Science, GRESPI Thermomechanical Lab; Tunis Univ., Tunis (Tunisia). Faculty of Science, EL MANAR, LETTM; Maad, B.R. [Tunis Univ., Tunis (Tunisia). Faculty of Science, EL MANAR, LETTM

    2010-07-01

    The efficiency of cooling methods in thermal systems such as radiators and heat exchangers must be improved in order to enhance performance. The evaluation of the heat transfer coefficients between a solid and a fluid is necessary for the control and the dimensioning of thermal systems. In this study, the pulsed photothermal method was used to measure the convective heat transfer coefficient on a solid-fluid interface, notably between an air flow and a heated slab mounted on a PVC flat plate. This configuration simulated the electronic air-cooling inside enclosures and racks. The influence of the deflector's inclination angle on the enhancement of heat transfer was investigated using 2 newly developed identification models. The first model was based on a constant heat transfer coefficient during the pulsed experiment, while the second, improved model was based on a variable heat transfer coefficient. The heat transfer coefficient was deduced from the evolution of the transient temperature induced by a sudden deposit of a luminous energy on the front face of the slab. Temperature evolutions were derived by infrared thermography, a camera for cartography and a detector for precise measurement in specific locations. The results show the improvement of measurement accuracies when using a model that considers the temporal evolution of the convective heat transfer coefficient. The deflection of air flow on the upper surface of the heated slab demonstrated better cooling of the slab by the deflection of air flow. 11 refs., 1 tab., 8 figs.

  14. Isothermal temperature reactivity coefficient measurement in TRIGA reactor

    International Nuclear Information System (INIS)

    Zagar, T.; Ravnik, M.; Trkov, A.

    2002-01-01

    Direct measurement of an isothermal temperature reactivity coefficient at room temperatures in TRIGA Mark II research reactor at Jozef Stefan Institute in Ljubljana is presented. Temperature reactivity coefficient was measured in the temperature range between 15 o C and 25 o C. All reactivity measurements were performed at almost zero reactor power to reduce or completely eliminate nuclear heating. Slow and steady temperature decrease was controlled using the reactor tank cooling system. In this way the temperatures of fuel, of moderator and of coolant were kept in equilibrium throughout the measurements. It was found out that TRIGA reactor core loaded with standard fuel elements with stainless steel cladding has small positive isothermal temperature reactivity coefficient in this temperature range.(author)

  15. Atmospheric diffusion wind tunnel with automatic measurement

    Energy Technology Data Exchange (ETDEWEB)

    Maki, S; Sakai, J; Murata, E

    1974-01-01

    A wind tunnel which permits estimates of atmospheric diffusion is described. Smoke from power plant smoke stacks, for example, can be simulated and traced to determine the manner of diffusion in the air as well as the grade of dilution. The wind tunnel is also capable of temperature controlled diffusion tests in which temperature distribution inside the wind tunnel is controlled. A minimum wind velocity of 10 cm can be obtained with accuracy within plus or minus 0.05 percent using a controlled direct current motor; diffusion tests are often made at low wind velocity. Fully automatic measurements can be obtained by using a minicomputer so that the operation and reading of the measuring instruments can be remotely controlled from the measuring chamber. (Air Pollut. Abstr.)

  16. Measuring device for the temperature coefficient of reactor moderators

    International Nuclear Information System (INIS)

    Nakano, Yuzo.

    1987-01-01

    Purpose: To rapidly determine by automatic calculation the temperature coefficient for moderators which has been determined so far by a log of manual processings. Constitution: Each of signals from a control rod position indicator, a reactor reactivity, instrument and moderator temperature meter are inputted, and each of the signals and designed valued for the doppler temperature coefficients are stored. Recurling calculation is conducted based on the reactivity and the moderator temperature at an interval where the temperature changes of the moderators are equalized at an identical control rod position, to determine isothermic coefficient. Then, the temperature coefficient for moderator are calculated from the isothermic coefficient and the doppler temperature coefficient. The relationship between the reactivity and the moderator temperature is plotted on a X-Y recorder. The stored signals and the calculated temperature coefficient for moderators are sequentially displayed and the results are printed out when the measurement is completed. According to the present device, since the real time processing is conducted, the processing time can be shortened remarkably. Accordingly, it is possible to save the man power for the test of the nuclear reactor and improve the reactor operation performance. (Kamimura, M.)

  17. Sensitivity of Rabbit Ventricular Action Potential and Ca2+ Dynamics to Small Variations in Membrane Currents and Ion Diffusion Coefficients

    Directory of Open Access Journals (Sweden)

    Yuan Hung Lo

    2013-01-01

    Full Text Available Little is known about how small variations in ionic currents and Ca2+ and Na+ diffusion coefficients impact action potential and Ca2+ dynamics in rabbit ventricular myocytes. We applied sensitivity analysis to quantify the sensitivity of Shannon et al. model (Biophys. J., 2004 to 5%–10% changes in currents conductance, channels distribution, and ion diffusion in rabbit ventricular cells. We found that action potential duration and Ca2+ peaks are highly sensitive to 10% increase in L-type Ca2+ current; moderately influenced by 10% increase in Na+-Ca2+ exchanger, Na+-K+ pump, rapid delayed and slow transient outward K+ currents, and Cl− background current; insensitive to 10% increases in all other ionic currents and sarcoplasmic reticulum Ca2+ fluxes. Cell electrical activity is strongly affected by 5% shift of L-type Ca2+ channels and Na+-Ca2+ exchanger in between junctional and submembrane spaces while Ca2+-activated Cl−-channel redistribution has the modest effect. Small changes in submembrane and cytosolic diffusion coefficients for Ca2+, but not in Na+ transfer, may alter notably myocyte contraction. Our studies highlight the need for more precise measurements and further extending and testing of the Shannon et al. model. Our results demonstrate usefulness of sensitivity analysis to identify specific knowledge gaps and controversies related to ventricular cell electrophysiology and Ca2+ signaling.

  18. Diffusivity and electrical resistivity measurements in rock matrix around fractures

    International Nuclear Information System (INIS)

    Kumpulainen, H.; Uusheimo, K.

    1989-12-01

    Microfracturing of rock matrix around permeable fractures was studied experimentally from drill core samples around major fractures. The methods used were diffusion measurements using a 36 Cl-tracer and electrical resistivity measurements. Rock samples were from the Romuvaara investigation site, the granite specimen around a partially filled carbonate fracture (KR4/333 m) and gneiss specimen around a slickenside fracture (KR1/645 m). A consistent difference of one to two orders of magnitude in the levels of the methods with regard to the effective diffusion coefficients for Cl - -ion was found, the electrical resistivity measurement giving higher values. On the basis of the diffusion measurements the diffusion porosities could be calculated but these remained one to two orders of magnitude lower than that expected for granitic rocks using the water saturation method. A possible reason for these differences could have been the low, in some cases 0.004 M NaC1-concentration in the diffusion experiments vs. the 1 M NaCl-concentration used in the electrical resistivity measurements. Due to the small number of specimens and cross sectional areas of only 2 cm 2 , rock inhomogeneity effects were significant making the interpretation of the results somewhat troublesome. Porosities on fracture surfaces seemed to be higher than in the deeper, more intact rock matrix

  19. The value of the apparent diffusion coefficient in MR diffusion weighted imaging for the differential diagnosis of sinonasal masses

    International Nuclear Information System (INIS)

    Wang Yongzhe; Yang Bentao; Xian Junfang; Li Jing; Chen Guangli

    2014-01-01

    Objective: To investigate the diagnostic value of apparent diffusion coefficient in the evaluation of sinonasal masses. Methods: Sixty-seven sinonasal solid masses over 1 cm in diameter confirmed by pathology were retrospectively analyzed, all patients underwent preoperative routine MRI with DWI, the ADC values were measured in ROI within the solid mass. The patients were divided into benign and malignant groups by the histopathology, according to pathological findings, the patients were further divided into the hematolymphoid tumors, the malignancy of epithelium and mesenchymal tissue, the benign tumors of epithelial and mesenchymal tissue, and vasogenic masses. ANOVA test and t test were used to compare the ADC values of different groups. The receiver operating characteristic curve (ROC) was constructed using various cut points of ADC for different parameters to confirm the diagnostic threshold value and evaluate the diagnostic efficacy. Results: All lesions were solitary. There were 22 malignant tumors, of which 6 lesions were hematolymphoid tumors and 16 lesions malignancy from epithelium and mesenchymal tissue. There were 45 benign tumors, of which 22 lesions were benign tumors from epithelium and mesenchymal tissue and 23 lesions vasogenic masses. The mean ADC value of malignant and benign masses was (0.88 ± 0.26) × 10 -3 mm 2 /s and (1.54 ± 0.41) × 10 -3 mm 2 /s respectively. There was statistically significant differences between them (t=6.897, P <0.01). The mean ADC value was(0.63 ± 0.10) × 10 -3 mm 2 /s in hematolymphoid tumors,(0.97 ±0.24) × 10 -3 mm 2 /s in malignancy from epithelium and mesenchymal tissue, (1.38 ± 0.23) × 10 -3 mm 2 /s in benign tumors from epithelium and mesenchymal tissue,(1.68 ± 0.49) × 10 -3 mm 2 /s in vasogenic masses respectively. There was statistically significant difference among all 4 groups(F=22.788, P<0.01), and the differences between any 2 groups were still statistically significant (P <0.05). The area under

  20. Limits of the memory coefficient in measuring correlated bursts

    Science.gov (United States)

    Jo, Hang-Hyun; Hiraoka, Takayuki

    2018-03-01

    Temporal inhomogeneities in event sequences of natural and social phenomena have been characterized in terms of interevent times and correlations between interevent times. The inhomogeneities of interevent times have been extensively studied, while the correlations between interevent times, often called correlated bursts, are far from being fully understood. For measuring the correlated bursts, two relevant approaches were suggested, i.e., memory coefficient and burst size distribution. Here a burst size denotes the number of events in a bursty train detected for a given time window. Empirical analyses have revealed that the larger memory coefficient tends to be associated with the heavier tail of the burst size distribution. In particular, empirical findings in human activities appear inconsistent, such that the memory coefficient is close to 0, while burst size distributions follow a power law. In order to comprehend these observations, by assuming the conditional independence between consecutive interevent times, we derive the analytical form of the memory coefficient as a function of parameters describing interevent time and burst size distributions. Our analytical result can explain the general tendency of the larger memory coefficient being associated with the heavier tail of burst size distribution. We also find that the apparently inconsistent observations in human activities are compatible with each other, indicating that the memory coefficient has limits to measure the correlated bursts.

  1. Quantitative Apparent Diffusion Coefficients in the Characterization of Brain Tumors and Associated Peritumoral Edema

    International Nuclear Information System (INIS)

    Server, A.; Schellhorn, T.; Nakstad, P.H.; Kulle, B.; Maehlen, J.; Kumar, T.; Josefsen, R.; Langberg, C.W.

    2009-01-01

    Background: Conventional magnetic resonance (MR) imaging has a number of limitations in the diagnosis of the most common intracranial brain tumors, including tumor specification and the detection of tumoral infiltration in regions of peritumoral edema. Purpose: To prospectively assess if diffusion-weighted MR imaging (DWI) could be used to differentiate between different types of brain tumors and to distinguish between peritumoral infiltration in high-grade gliomas, lymphomas, and pure vasogenic edema in metastases and meningiomas. Material and Methods: MR imaging and DWI was performed on 93 patients with newly diagnosed brain tumors: 59 patients had histologically verified high-grade gliomas (37 glioblastomas multiforme, 22 anaplastic astrocytomas), 23 patients had metastatic brain tumors, five patients had primary cerebral lymphomas, and six patients had meningiomas. Apparent diffusion coefficient (ADC) values of tumor (enhancing regions or the solid portion of tumor) and peritumoral edema, and ADC ratios (ADC of tumor or peritumoral edema to ADC of contralateral white matter, ADC of tumor to ADC of peritumoral edema) were compared with the histologic diagnosis. ADC values and ratios of high-grade gliomas, primary cerebral lymphomas, metastases, and meningiomas were compared by using ANOVA and multiple comparisons. Optimal thresholds of ADC values and ADC ratios for distinguishing high-grade gliomas from metastases were determined by receiver operating characteristic (ROC) curve analysis. Results: Statistically significant differences were found for minimum and mean of ADC tumor and ADC tumor ratio values between metastases and high-grade gliomas when including only one factor at a time. Including a combination of in total four parameters (mean ADC tumor, and minimum, maximum and mean ADC tumor ratio) resulted in sensitivity, specificity, positive (PPV), and negative predictive values (NPV) of 72.9, 82.6, 91.5, and 54.3% respectively. In the ROC curve analysis

  2. The off-center effect on the diffusion coefficient of Cu+ and Li+ in the KCl lattice

    International Nuclear Information System (INIS)

    Despa, F.

    1994-07-01

    It is well known that the diffusion coefficients of the Cu + cation in the NaCl and KCl lattices exceeds by three or four orders of magnitude the corresponding self-diffusion coefficients in the intrinsic temperature regions. This fast diffusion of the Cu + has been explained in many papers as an interstitial diffusion although the optical spectra do not confirm the existence of interstitial Cu + . In this paper we propose a new mechanism for fast diffusion. The model assumes that the equilibrium positions of the cationic impurities are noncentral and that the diffusion proceeds by hopping across the potential barrier along the nonlinear paths with the highest probability. The main result shows that the off-center position enhances considerably the diffusion. Theoretical diffusion coefficients have been obtained by modelling the potential barrier. Changes of the configuration entropy and the vibration spectra due to the presence of the noncentral impurity have been included in the model. We proceeded in the Li + cation case as in the case of Cu + cation. We emphasize the good agreement of the model with the experimental data and we show that if the impurity is placed close to the central site the due diffusion coefficient is close to that for the cationic self-diffusion. (author). 37 refs, 6 figs, 3 tabs

  3. Diffusivity measurements of volatile organics in levitated viscous aerosol particles

    Directory of Open Access Journals (Sweden)

    S. Bastelberger

    2017-07-01

    Full Text Available Field measurements indicating that atmospheric secondary organic aerosol (SOA particles can be present in a highly viscous, glassy state have spurred numerous studies addressing low diffusivities of water in glassy aerosols. The focus of these studies is on kinetic limitations of hygroscopic growth and the plasticizing effect of water. In contrast, much less is known about diffusion limitations of organic molecules and oxidants in viscous matrices. These may affect atmospheric chemistry and gas–particle partitioning of complex mixtures with constituents of different volatility. In this study, we quantify the diffusivity of a volatile organic in a viscous matrix. Evaporation of single particles generated from an aqueous solution of sucrose and small amounts of volatile tetraethylene glycol (PEG-4 is investigated in an electrodynamic balance at controlled relative humidity (RH and temperature. The evaporative loss of PEG-4 as determined by Mie resonance spectroscopy is used in conjunction with a radially resolved diffusion model to retrieve translational diffusion coefficients of PEG-4. Comparison of the experimentally derived diffusivities with viscosity estimates for the ternary system reveals a breakdown of the Stokes–Einstein relationship, which has often been invoked to infer diffusivity from viscosity. The evaporation of PEG-4 shows pronounced RH and temperature dependencies and is severely depressed for RH ≲ 30 %, corresponding to diffusivities < 10−14 cm2 s−1 at temperatures < 15 °C. The temperature dependence is strong, suggesting a diffusion activation energy of about 300 kJ mol−1. We conclude that atmospheric volatile organic compounds can be subject to severe diffusion limitations in viscous organic aerosol particles. This may enable an important long-range transport mechanism for organic material, including pollutant molecules such as polycyclic aromatic hydrocarbons (PAHs.

  4. Validity of apparent diffusion coefficient hyperpolarized 3He-MRI using MSCT and pulmonary function tests as references

    DEFF Research Database (Denmark)

    Diaz, Sandra; Casselbrant, Ingrid; Piitulainen, Eeva

    2008-01-01

    PURPOSE: To compare apparent diffusion coefficient (ADC) measurements from hyperpolarized (HP) helium ((3)He)-magnetic resonance imaging (MRI) with quantitative data from multislice Computed Tomography (CT) (MSCT) of the whole lungs and pulmonary function tests (PFT). MATERIALS AND METHODS: Twenty......-seven subjects, 22 with established emphysema and 5 with preclinical emphysema defined by PFT criteria, were examined with HP (3)He-MRI and MSCT. Mean age was 55 (+/-12) years, 18 female and 9 male. Mean ADC from (3)He-MRI was compared with emphysema index (EI), 15th percentile and mean lung density (MLD) values...... from MSCT. Both mean ADC and MSCT data were compared to PFT, especially percent of predicted diffusing capacity of carbon monoxide (%predicted DLCO), using Pearson's correlation test. RESULTS: Mean ADC and standard deviation values were 0.392+/-0.119 cm(2)/s for the established emphysema group and 0...

  5. Usefulness of Apparent Diffusion Coefficient Values in the Nasopharynx and the Oropharynx: Differentiation of Benign and Malignant Lesions

    International Nuclear Information System (INIS)

    Kwon, Hoon; Kim, Hak Jin; Sol, Yu Li; Lee, Tae Hong; Yeom, Jeong A; Kim, Ah Rong

    2012-01-01

    In several previous studies, apparent diffusion coefficient (ADC) calculation was applied in the evaluation of head and neck tumors and is a promising technique for this application. As a result, we reevaluated the usefulness of ADC measurement with differentiation of benign and malignant pathology in the nasopharynx and oropharynx. The study population consisted of 87 consecutive patients who had undergone routine nasopharyngeal and oropharyngeal MR imaging at our institution, which included diffusion weighted image and ADC map, with a clinically suspected primary tumor of nasopharynx and oropharynx. The mean ADC values in the benign and malignant groups were compared and the malignant group was divided into the lymphoma and carcinoma groups. A statistically significant difference in ADC values among the benign and malignant groups using independent samples t-test with a p -3 mm 2 /s was used to distinguish between benign and malignancy, accuracy was 85%. ADC values were useful for distinguishing between benign and malignancy in the nasopharynx and oropharynx.

  6. Accuracy of apparent diffusion coefficient in differentiating pancreatic neuroendocrine tumour from intrapancreatic accessory spleen

    International Nuclear Information System (INIS)

    Pandey, Ankur; Pandey, Pallavi; Ghasabeh, Mounes Aliyari; Varzaneh, Farnaz Najmi; Khoshpouri, Pegah; Shao, Nannan; Pour, Manijeh Zargham; Fouladi, Daniel Fadaei; Kamel, Ihab R.; Hruban, Ralph H.; O'Broin-Lennon, Anne Marie

    2018-01-01

    To evaluate and compare the accuracy of absolute apparent diffusion coefficient (ADC) and normalised ADC (lesion-to-spleen ADC ratio) in differentiating pancreatic neuroendocrine tumour (NET) from intrapancreatic accessory spleen (IPAS). Study included 62 patients with the diagnosis of pancreatic NET (n=51) or IPAS (n=11). Two independent reviewers measured ADC on all lesions and spleen. Receiver operating characteristics (ROC) analysis to differentiate NET from IPAS was performed and compared for absolute and normalised ADC. Inter-reader reliability for the two methods was assessed. Pancreatic NET had significantly higher absolute ADC (1.431 x 10 -3 vs 0.967 x 10 -3 mm 2 /s; P<0.0001) and normalised ADC (1.59 vs 1.09; P<0.0001) compared to IPAS. An ADC value of ≥1.206 x 10 -3 mm 2 /s was 70.6% sensitive and 90.9% specific for the diagnosis of NET vs. IPAS. Lesion to spleen ADC ratio of ≥1.25 was 80.4% sensitive, and 81.8% specific while ratio of ≥1.29 was 74.5% sensitive and 100% specific in the differentiation. The area under the curve (AUCs) for two methods were similar (88.2% vs. 88.8%; P=0.899). Both methods demonstrated excellent inter-reader reliability with ICCs for absolute ADC and ADC ratio being 0.957 and 0.927, respectively. Both absolute and normalised ADC allow clinically relevant differentiation of pancreatic NET and IPAS. (orig.)

  7. Computing the blood brain barrier (BBB) diffusion coefficient: A molecular dynamics approach

    Energy Technology Data Exchange (ETDEWEB)

    Shamloo, Amir, E-mail: shamloo@sharif.edu; Pedram, Maysam Z.; Heidari, Hossein; Alasty, Aria, E-mail: aalasti@sharif.edu

    2016-07-15

    Various physical and biological aspects of the Blood Brain Barrier (BBB) structure still remain unfolded. Therefore, among the several mechanisms of drug delivery, only a few have succeeded in breaching this barrier, one of which is the use of Magnetic Nanoparticles (MNPs). However, a quantitative characterization of the BBB permeability is desirable to find an optimal magnetic force-field. In the present study, a molecular model of the BBB is introduced that precisely represents the interactions between MNPs and the membranes of Endothelial Cells (ECs) that form the BBB. Steered Molecular Dynamics (SMD) simulations of the BBB crossing phenomenon have been carried out. Mathematical modeling of the BBB as an input-output system has been considered from a system dynamics modeling viewpoint, enabling us to analyze the BBB behavior based on a robust model. From this model, the force profile required to overcome the barrier has been extracted for a single NP from the SMD simulations at a range of velocities. Using this data a transfer function model has been obtained and the diffusion coefficient is evaluated. This study is a novel approach to bridge the gap between nanoscale models and microscale models of the BBB. The characteristic diffusion coefficient has the nano-scale molecular effects inherent, furthermore reducing the computational costs of a nano-scale simulation model and enabling much more complex studies to be conducted. - Highlights: • Molecular dynamics simulation of crossing nano-particles through the BBB membrane at different velocities. • Recording the position of nano-particle and the membrane-NP interaction force profile. • Identification of a frequency domain model for the membrane. • Calculating the diffusion coefficient based on MD simulation and identified model. • Obtaining a relation between continuum medium and discrete medium.

  8. Apparent diffusion coefficients of normal uterus in premenopausal women with 3 T MRI

    International Nuclear Information System (INIS)

    Kuang, F.; Chen, Z.; Zhong, Q.; Fu, L.; Ma, M.

    2013-01-01

    Aim: To investigate the apparent diffusion coefficient (ADC) values of the normal uterine cervical zonal structures (cervical epithelium, the junctional zone, and myometrium) during different phases of the menstrual cycle among premenopausal women in different age groups. Materials and methods: Seventy healthy women, who were divided into three age groups (group A, 24 women in their twenties; group B, 23 women in their thirties; group C, 23 women in their forties), underwent 3 T magnetic resonance imaging (MRI) with T2-weighted and diffusion-weighted imaging (DWI) during the mid-proliferative and the mid-secretory phases. Results: The ADC values of each cervical zonal structure were significantly different from one another (p 0.05). Conclusion: ADC values of normal cervical epithelium and the junctional zone change with different phases of the menstrual cycle, which should be taken into consideration when early cervical disease is detected, when monitoring treatment response, and differentiating early tumour recurrence

  9. Determination of diffusion coefficients in Au/Ni thin films by Auger electron spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Abdul-Lettif, Ahmed M. [Physics Department, College of Science, Babylon University, Hilla (Iraq)

    2004-07-01

    Interdiffusion in vacuum-deposited Au/Ni thin films at temperatures in the range 200-500 C has been investigated using the Auger depth profiling technique and X-ray diffraction analysis. A modified Wipple model was used to determine the diffusion coefficients of Ni in Au to be 5.3 x 10{sup -16} cm{sup 2}/s at 500 C, 4.0 x 10{sup -17} cm{sup 2}/s at 400 C, 2.5 x 10{sup -18} cm{sup 2}/s at 300 C, and 1.2 x 10{sup -19} cm{sup 2}/s at 200 C. An activation energy of 0.87 eV was calculated. The present diffusion data differ significantly from the corresponding values extracted by some other investigators and the reasons for this disagreement were discussed. (copyright 2004 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  10. Whole-Lesion Histogram Analysis of Apparent Diffusion Coefficient for the Assessment of Cervical Cancer.

    Science.gov (United States)

    Guan, Yue; Shi, Hua; Chen, Ying; Liu, Song; Li, Weifeng; Jiang, Zhuoran; Wang, Huanhuan; He, Jian; Zhou, Zhengyang; Ge, Yun

    2016-01-01

    The aim of this study was to explore the application of whole-lesion histogram analysis of apparent diffusion coefficient (ADC) values of cervical cancer. A total of 54 women (mean age, 53 years) with cervical cancers underwent 3-T diffusion-weighted imaging with b values of 0 and 800 s/mm prospectively. Whole-lesion histogram analysis of ADC values was performed. Paired sample t test was used to compare differences in ADC histogram parameters between cervical cancers and normal cervical tissues. Receiver operating characteristic curves were constructed to identify the optimal threshold of each parameter. All histogram parameters in this study including ADCmean, ADCmin, ADC10%-ADC90%, mode, skewness, and kurtosis of cervical cancers were significantly lower than those of normal cervical tissues (all P histogram analysis of ADC maps is useful in the assessment of cervical cancer.

  11. Apparent diffusion coefficient of the renal tissue. The effect of diuretic

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Jin; Munechika, Hirotsugu [Showa Univ., Tokyo (Japan). School of Medicine

    1998-12-01

    Apparent diffusion coefficient (ADC) of the renal tissue was studied at diffusion-weighted images of the kidney which were obtained from spin-echo type sequence before and after furosemide (100 mg) injection in twelve healthy volunteers. ADC (mm{sup 2}/sec) of the renal cortex and medulla before furosemide injection was 2.08{+-}0.52 and 1.96{+-}0.52, respectively. No appreciable ADC difference was seen between the cortex and the medulla of the kidney. After furosemide injection, ADC of the renal cortex and medulla became 2.09{+-}0.42 and 1.78{+-}0.38, respectively. It was found that furosemide produced no significant effect on ADC of the renal tissue. (author)

  12. Turbulent-diffusion vertical transfer coefficient in relationship to the electrical parameters of air

    International Nuclear Information System (INIS)

    Milhau, A.

    1971-01-01

    The vertical movement of ions in the lower atmosphere is due to two main causes: the atmospheric electrical field and turbulent diffusion. The vertical current is thus the sum of a conduction current and of a diffusion current. In order to resolve the discrepancies between the theories usually adopted (which neglect the diffusion current) and the experimental results, we propose here a theoretical model which takes into account the turbulent diffusion. This model makes it possible, if it is assumed that the conductivity is independent of the altitude in the exchange layer, to calculate the diffusivity from the three basic electrical parameters: electrical field, space charge, conductivity. The diffusivity values thus obtained have been compared to those deduced from thoron determinations made at different levels, and carried out at the same point and at the same time as the measurements of the electrical parameters. When the diffusivity is greater than 0.05 m 2 s -1 (this corresponding to adiabatic or super-adiabatic conditions) the values obtained are practically equal. This theoretical model thus appears to be satisfactory. (author) [fr

  13. A finite difference method for space fractional differential equations with variable diffusivity coefficient

    KAUST Repository

    Mustapha, K.

    2017-06-03

    Anomalous diffusion is a phenomenon that cannot be modeled accurately by second-order diffusion equations, but is better described by fractional diffusion models. The nonlocal nature of the fractional diffusion operators makes substantially more difficult the mathematical analysis of these models and the establishment of suitable numerical schemes. This paper proposes and analyzes the first finite difference method for solving {\\\\em variable-coefficient} fractional differential equations, with two-sided fractional derivatives, in one-dimensional space. The proposed scheme combines first-order forward and backward Euler methods for approximating the left-sided fractional derivative when the right-sided fractional derivative is approximated by two consecutive applications of the first-order backward Euler method. Our finite difference scheme reduces to the standard second-order central difference scheme in the absence of fractional derivatives. The existence and uniqueness of the solution for the proposed scheme are proved, and truncation errors of order $h$ are demonstrated, where $h$ denotes the maximum space step size. The numerical tests illustrate the global $O(h)$ accuracy of our scheme, except for nonsmooth cases which, as expected, have deteriorated convergence rates.

  14. Self-diffusion coefficient of iron as affected by chelating agents using tracer technique

    Energy Technology Data Exchange (ETDEWEB)

    Massoud, M.A.; Abd-El-Sabour, M.F. (Agriculture Dept. for Soil and Water Research, Nuclear Research Centre, A.E.A., Cairo (Egypt)); Omar, M.A. (Ain Shams Univ., Cairo (Egypt). Faculty of Agriculture)

    1983-01-01

    The effect of Fe/sub 2/(So/sub 4/)/sub 3/, Fe-DTPA, and Fe-EDDHA on the self-diffusion coefficient of Fe in some soils of Egypt was studied. The effect of chelating compounds on the ratio between solid phase fraction of the labile Fe and its concentration in the soil solution (capacity factor) was also studied. The data reveals the following items of more interesting: 1) The use of chelating agents, i.e., DTPA and EDDHA increased the amount of Fe in soil solution, hence the capacity factor was decreased using these compounds. It seems that as the addition of Fe was in the chelated form in soil solution, the slight loss of 59Fe from solution when 59Fe - chelate was used could be attributed to the isotopic exchange with soil Fe. 2) It was found that the addition of either Fe-DTPA or Fe-EDDHA significantly increased the self-diffusion of Fe in soil as compared with Fe/sub 2/(So/sub 4/)/sub 3/. It was also noticed that the self-diffusion for Fe in the alluvial soil was greater than in the calcareous one due to the instance competition between Ca and Fe for the chelating ligands in the calcareous soil. It was also seen that soil texture affects Fe self-diffusion.

  15. Self-diffusion coefficient of iron as affected by chelating agents using tracer technique

    International Nuclear Information System (INIS)

    Massoud, M.A.; Abd-El-Sabour, M.F.; Omar, M.A.

    1983-01-01

    The effect of Fe 2 (So 4 ) 3 , Fe-DTPA, and Fe-EDDHA on the self-diffusion coefficient of Fe in some soils of Egypt was studied. The effect of chelating compounds on the ratio between solid phase fraction of the labile Fe and its concentration in the soil solution (capacity factor) was also studied. The data reveals the following items of more interesting: 1) The use of chelating agents, i.e., DTPA and EDDHA increased the amount of Fe in soil solution, hence the capacity factor was decreased using these compounds. It seems that as the addition of Fe was in the chelated form in soil solution, the slight loss of 59Fe from solution when 59Fe - chelate was used could be attributed to the isotopic exchange with soil Fe. 2) It was found that the addition of either Fe-DTPA or Fe-EDDHA significantly increased the self-diffusion of Fe in soil as compared with Fe 2 (So 4 ) 3 . It was also noticed that the self-diffusion for Fe in the alluvial soil was greater than in the calcareous one due to the instance competition between Ca and Fe for the chelating ligands in the calcareous soil. It was also seen that soil texture affects Fe self-diffusion

  16. A finite difference method for space fractional differential equations with variable diffusivity coefficient

    KAUST Repository

    Mustapha, K.; Furati, K.; Knio, Omar; Maitre, O. Le

    2017-01-01

    Anomalous diffusion is a phenomenon that cannot be modeled accurately by second-order diffusion equations, but is better described by fractional diffusion models. The nonlocal nature of the fractional diffusion operators makes substantially more difficult the mathematical analysis of these models and the establishment of suitable numerical schemes. This paper proposes and analyzes the first finite difference method for solving {\\em variable-coefficient} fractional differential equations, with two-sided fractional derivatives, in one-dimensional space. The proposed scheme combines first-order forward and backward Euler methods for approximating the left-sided fractional derivative when the right-sided fractional derivative is approximated by two consecutive applications of the first-order backward Euler method. Our finite difference scheme reduces to the standard second-order central difference scheme in the absence of fractional derivatives. The existence and uniqueness of the solution for the proposed scheme are proved, and truncation errors of order $h$ are demonstrated, where $h$ denotes the maximum space step size. The numerical tests illustrate the global $O(h)$ accuracy of our scheme, except for nonsmooth cases which, as expected, have deteriorated convergence rates.

  17. A fast collocation method for a variable-coefficient nonlocal diffusion model

    Science.gov (United States)

    Wang, Che; Wang, Hong

    2017-02-01

    We develop a fast collocation scheme for a variable-coefficient nonlocal diffusion model, for which a numerical discretization would yield a dense stiffness matrix. The development of the fast method is achieved by carefully handling the variable coefficients appearing inside the singular integral operator and exploiting the structure of the dense stiffness matrix. The resulting fast method reduces the computational work from O (N3) required by a commonly used direct solver to O (Nlog ⁡ N) per iteration and the memory requirement from O (N2) to O (N). Furthermore, the fast method reduces the computational work of assembling the stiffness matrix from O (N2) to O (N). Numerical results are presented to show the utility of the fast method.

  18. Theoretical treatment of equilibrium data and evaluation of diffusion coefficients in extraction of uranium

    Energy Technology Data Exchange (ETDEWEB)

    Manohar, Smitha; Theyyunni, T K [Process Engineering and Systems Development Division, Bhabha Atomic Research Centre, Mumbai (India); Ragunathan, T S [Department of Chemical Engineering, Indian Inst. of Tech., Mumbai (India)

    1994-06-01

    A meaningful approach to the calculation of the performance of solvent extraction contactors in the PUREX process requires a good understanding of the equilibrium distribution of the important constituents, namely uranyl nitrate and nitric acid. Published literature refers to the empirical correlation of the distribution data, generally in the form of polynomials. Attempts are made to describe the distribution data in a form which is specially convenient for numerical computations along with its theoretical significance. Attempts are also made to derive suitable equations which would aid in estimation of diffusion coefficients in the uranyl nitrate-nitric acid-TBP/diluent system. (author). 2 tabs.

  19. Eddy diffusion coefficients in the coastal waters of north Andhra Pradesh and Orissa

    Digital Repository Service at National Institute of Oceanography (India)

    Sadhuram, Y.; Murty, T.V.R.; Rao, B.P.; Sarma, V.V.

    diffusion coefficients in coastal waters The unknown variables v and \\v can be f ound by solving the matrix. In the present work, the method of generalized inverse is used to solve the matrix to avoid any indeterminacy. Results and discussion Temperature... was constant (~24.3?C) and salinity fluctuates around 27.5 psu. Off Gopalpur (IV) strong inversion of 1.87? C was observed during the observational period. Temperature profiles at areas V and VI indicate 125 Mathematical Formulations: The two...

  20. Determination of diffusion coefficients in cohesive and sandy sediment from the area of Gorleben

    International Nuclear Information System (INIS)

    Klotz, D.

    1989-01-01

    The cohesive and sandy sediments stem from shaft driving at the Gorleben salt done. For the cohesive materials, HTD was used as a tracer substance, while I-131 - was used for the sandy materials. Diffusion coefficients of HTD in cohesive materials in their natural texture are in the range of 2x10 -6 to 5x10 -6 cm 2 /s, those of I-131 - in the investigated uniform fine and middle sands are approximately 3x10 -6 cm 2 /s. (DG) [de

  1. A simple formalism for diffusion coefficient calculations in cells having a small optical thickness

    International Nuclear Information System (INIS)

    Benoist, Pierre.

    1980-04-01

    A very simple formalism, using directionnal first flight collision probabilities, is established; it is assigned to the calculation of the diffusion coefficients in cells having a small optical thickness. This formalism can be used, at least as a first approximation, in lattices of sodium-cooled fast reactors or of light water reactors. However, due to the two assumptions -cylindricalization of the cell and restriction to the zeroth order term in B 2 (k)- this formalissm cannot be used for sodium-voided or gas-cooled fast reactor lattices [fr

  2. Improvement of calculation method for temperature coefficient of HTTR by neutronics calculation code based on diffusion theory. Analysis for temperature coefficient by SRAC code system

    International Nuclear Information System (INIS)

    Goto, Minoru; Takamatsu, Kuniyoshi

    2007-03-01

    The HTTR temperature coefficients required for the core dynamics calculations had been calculated from the HTTR core calculation results by the diffusion code with which the corrections had been performed using the core calculation results by the Monte-Carlo code MVP. This calculation method for the temperature coefficients was considered to have some issues to be improved. Then, the calculation method was improved to obtain the temperature coefficients in which the corrections by the Monte-Carlo code were not required. Specifically, from the point of view of neutron spectrum calculated by lattice calculations, the lattice model was revised which had been used for the calculations of the temperature coefficients. The HTTR core calculations were performed by the diffusion code with the group constants which were generated by the lattice calculations with the improved lattice model. The core calculations and the lattice calculations were performed by the SRAC code system. The HTTR core dynamics calculation was performed with the temperature coefficient obtained from the core calculation results. In consequence, the core dynamics calculation result showed good agreement with the experimental data and the valid temperature coefficient could be calculated only by the diffusion code without the corrections by Monte-Carlo code. (author)

  3. Uranium self-diffusion in uranium monocarbide; Determination du coefficient d'autodiffusion de l'uranium dans son monocarbure

    Energy Technology Data Exchange (ETDEWEB)

    Villaine, P [Commissariat a l' Energie Atomique, 38 - Grenoble (France). Centre d' Etudes Nucleaires

    1967-10-01

    Uranium self diffusion in near-stoichiometric stabilized uranium monocarbide has been investigated in the temperature range 1450-2000 deg. C. A thin layer of {sup 235}UC was deposited onto the samples and the diffusion profiles were analyzed by both sectioning and alpha-spectrometry techniques. The variation with temperature of the self-diffusion coefficient can be expressed by the equation: D = 7.5 x 10{sup -5} exp [-(81 {+-} 10) kcal/mole / RT] Cm{sup 2} s{sup -1} The coefficient D decreases with increasing carbon content. Autoradiographs and profile analysis have evidenced a preferential grain-boundary diffusion at all temperatures and compositions investigated. This phenomenon was used for a study of grain-boundary migration and for the evaluation of grain-boundary diffusion coefficients. The activation energy thus derived is close to the volume diffusion activation energy. (author) [French] L'autodiffusion de l'uranium dans le monocarbure d'uranium de composition voisine de la stoechiometrie et stabilise par recuit prealable, a ete etudiee entre 1450 et 2000 deg. C par la methode du depot mince de traceur, suivie des techniques d'abrasion comptage et de spectrometrie alpha. La variation avec la temperature du coefficient d'autodiffusion peut s'ecrire: D = 7.5 x 10{sup -5} exp [-(81 {+-} 10) kcal/mole / RT] Cm{sup 2} s{sup -1} Le coefficient D decroit avec une augmentation de la teneur en carbone. L'observation d'autoradiographies et l'analyse de profils de diffusion ont mis en evidence l'importance d'une diffusion intergranulaire preferentielle pour toutes les compositions etudiees et a toutes les temperatures. Cette diffusion a egalement ete utilisee pour l'etude de la migration des joints de grains et pour le calcul approche du coefficient de diffusion mtergranulaire. L'energie d'activation ainsi determinee est voisine de celle correspondant a la diffusion volumique. (auteur)

  4. Techniques For Measuring Absorption Coefficients In Crystalline Materials

    Science.gov (United States)

    Klein, Philipp H.

    1981-10-01

    Absorption coefficients smaller than 0.001 cm-1 can, with more or less difficulty, be measured by several techniques. With diligence, all methods can be refined to permit measurement of absorption coefficients as small as 0.00001 cm-1. Spectral data are most readily obtained by transmission (spectrophotometric) methods, using multiple internal reflection to increase effective sample length. Emissivity measurements, requiring extreme care in the elimination of detector noise and stray light, nevertheless afford the most accessible spectral data in the 0.0001 to 0.00001 cm-1 range. Single-wavelength informa-tion is most readily obtained with modifications of laser calorimetry. Thermo-couple detection of energy absorbed from a laser beam is convenient, but involves dc amplification techniques and is susceptible to stray-light problems. Photoacoustic detection, using ac methods, tends to diminish errors of these types, but at some expense in experimental complexity. Laser calorimetry has been used for measurements of absorption coefficients as small as 0.000003 cm-1. Both transmission and calorimetric data, taken as functions of intensity, have been used for measurement of nonlinear absorption coefficients.

  5. Correlation between apparent diffusion coefficient value on diffusion-weighted MR imaging and Gleason score in prostate cancer.

    Science.gov (United States)

    Wu, X; Reinikainen, P; Vanhanen, A; Kapanen, M; Vierikko, T; Ryymin, P; Hyödynmaa, S; Kellokumpu-Lehtinen, P-L

    2017-01-01

    To investigate whether diffusion-weighted imaging (DWI) apparent diffusion coefficient (ADC) correlates with prostate cancer aggressiveness and further to compare the diagnostic performance of ADC and normalized ADC (nADC: normalized to non-tumor tissue). Thirty pre-treatment patients (mean age, 69years; range: 59-78years) with prostate cancer underwent magnetic resonance imaging (MRI) examination, including DWI with three b values: 50, 400, and 800s/mm 2 . Both ADC and nADC were correlated with the Gleason score obtained through transrectal ultrasound-guided biopsy. The tumor minimum ADC (ADC min : the lowest ADC value within tumor) had an inverse correlation with the Gleason score (r=-0.43, Pcorrelated with the Gleason score (r=-0.52 and r=-0.55, P<0.01; respectively), and they were lower in patients with Gleason score 3+4 than those with Gleason score 3+3 (P<0.01; respectively). Receiver operating characteristic (ROC) analysis showed that the area under the ROC curve was 0.765, 0.818, or 0.833 for the ADC min , nADC min , or nADC mean ; respectively, in differentiating between Gleason score 3+4 and 3+3 tumors. Tumor ADC min , nADC min , and nADC mean are useful markers to predict the aggressiveness of prostate cancer. Copyright © 2016 Éditions françaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

  6. Apparent diffusion coefficient of vertebral haemangiomas allows differentiation from malignant focal deposits in whole-body diffusion-weighted MRI

    International Nuclear Information System (INIS)

    Winfield, Jessica M.; Blackledge, Matthew D.; Collins, David J.; Tunariu, Nina; Messiou, Christina; Poillucci, Gabriele; Shah, Vallari; Kaiser, Martin F.

    2018-01-01

    The aim of this study was to identify apparent diffusion coefficient (ADC) values for typical haemangiomas in the spine and to compare them with active malignant focal deposits. This was a retrospective single-institution study. Whole-body magnetic resonance imaging (MRI) scans of 106 successive patients with active multiple myeloma, metastatic prostate or breast cancer were analysed. ADC values of typical vertebral haemangiomas and malignant focal deposits were recorded. The ADC of haemangiomas (72 ROIs, median ADC 1,085 x 10 -6 mm 2 s -1 , interquartile range 927-1,295 x 10 -6 mm 2 s -1 ) was significantly higher than the ADC of malignant focal deposits (97 ROIs, median ADC 682 x 10 -6 mm 2 s -1 , interquartile range 583-781 x 10 -6 mm 2 s -1 ) with a p-value < 10 -6 . Receiver operating characteristic (ROC) analysis produced an area under the curve of 0.93. An ADC threshold of 872 x 10 -6 mm 2 s -1 separated haemangiomas from malignant focal deposits with a sensitivity of 84.7 % and specificity of 91.8 %. ADC values of classical vertebral haemangiomas are significantly higher than malignant focal deposits. The high ADC of vertebral haemangiomas allows them to be distinguished visually and quantitatively from active sites of disease, which show restricted diffusion. (orig.)

  7. Interpatient variation in normal peripheral zone apparent diffusion coefficient: effect on the prediction of prostate cancer aggressiveness

    NARCIS (Netherlands)

    Litjens, G.J.S.; Hambrock, T.; Hulsbergen-van de Kaa, C.A.; Barentsz, J.O.; Huisman, H.J.

    2012-01-01

    Purpose: To determine the interpatient variability of prostate peripheral zone (PZ) apparent diffusion coefficient (ADC) and its effect on the assessment of prostate cancer aggressiveness. Materials and Methods: The requirement for institutional review board approval was waived. Intra- and

  8. Estimation of Knudsen diffusion coefficients from tracer experiments conducted with a binary gas system and a porous medium

    Science.gov (United States)

    Hibi, Yoshihiko; Kashihara, Ayumi

    2018-03-01

    A previous study has reported that Knudsen diffusion coefficients obtained by tracer experiments conducted with a binary gas system and a porous medium are consistently smaller than those obtained by permeability experiments conducted with a single-gas system and a porous medium. To date, however, that study is the only one in which tracer experiments have been conducted with a binary gas system. Therefore, to confirm this difference in Knudsen diffusion coefficients, we used a method we had developed previously to conduct tracer experiments with a binary carbon dioxide-nitrogen gas system and five porous media with permeability coefficients ranging from 10-13 to 10-11 m2. The results showed that the Knudsen diffusion coefficient of N2 (DN2) (cm2/s) was related to the effective permeability coefficient ke (m2) as DN2 = 7.39 × 107ke0.767. Thus, the Knudsen diffusion coefficients of N2 obtained by our tracer experiments were consistently 1/27 of those obtained by permeability experiments conducted with many porous media and air by other researchers. By using an inversion simulation to fit the advection-diffusion equation to the distribution of concentrations at observation points calculated by mathematically solving the equation, we confirmed that the method used to obtain the Knudsen diffusion coefficient in this study yielded accurate values. Moreover, because the Knudsen diffusion coefficient did not differ when columns with two different lengths, 900 and 1500 mm, were used, this column property did not influence the flow of gas in the column. The equation of the dusty gas model already includes obstruction factors for Knudsen diffusion and molecular diffusion, which relate to medium heterogeneity and tortuosity and depend only on the structure of the porous medium. Furthermore, there is no need to take account of any additional correction factor for molecular diffusion except the obstruction factor because molecular diffusion is only treated in a multicomponent

  9. Using Plasticine (TM) to Measure the Rolling Friction Coefficient.

    Science.gov (United States)

    Castellvi, Francesc; And Others

    1995-01-01

    Presents an experiment that makes manifest the energy lost to friction of an iron ball moving along an inclined iron rail, which allows students to compute the rolling friction coefficient. Uses a method based on measurement of deformation produced in a piece of Plasticine by an inelastic collision with the ball and combines mechanical concepts…

  10. Measurements of gaseous multiplication coefficient in pure isobutane

    International Nuclear Information System (INIS)

    Lima, Iara Batista de

    2010-01-01

    In this work it is presented measurements of gaseous multiplication coefficient (α) in pure isobutane obtained with a parallel plate chamber, protected against discharges by one electrode (anode) of high resistivity glass (ρ = 2 x 10 12 Ω.cm). The method applied was the Pulsed Townsend, where the primary ionization is produced through the incidence of a nitrogen laser beam onto a metallic electrode (cathode). The electric currents measured with the chamber operating in both ionization and avalanche regimes were used to calculate the gaseous multiplication coefficient by the solution of the Townsend equation for uniform electric fields. The validation of the technique was provided by the measurements of gaseous multiplication coefficient in pure nitrogen, a widely studied gas, which has well-established data in literature. The α coefficients in isobutane were measured as a function of the reduced electric field in the range of 139Td up to 208Td. The obtained values were compared with those simulated by Imonte software (version 4.5) and the only experimental results available in the literature, recently obtained in our group. This comparison showed that the results are concordant within the experimental errors. (author)

  11. Measurement of atomic number and mass attenuation coefficient in ...

    Indian Academy of Sciences (India)

    literature on the measurement of mass attenuation coefficient in magnesium ferrite. The knowledge of photon ... pure) MgO and Fe2O3. The details of experimental ... and (4 4 0) planes belonging to cubic spinel structure. The XRD pattern ...

  12. Thermal lensing measurement from the coefficient of defocus aberration

    CSIR Research Space (South Africa)

    Bell, Teboho

    2016-03-01

    Full Text Available We measured the thermally induced lens from the coefficient of defocus aberration using a Shack-Hartmann wavefront sensor (SHWFS). As a calibration technique, we infer the focal length of standard lenses probed by a collimated Gaussian beam...

  13. Homogenization of the coefficient of diffusion: influence of modelling and of the laplacian for fast power reactors and experimental mockups

    International Nuclear Information System (INIS)

    Gho, C.J.

    1984-10-01

    Neutron transport calculation of reactors is based on the definition of homogeneized cell constants, the diffusion coefficient among others. The formalism of the evaluation of the diffusion coefficient, as also the cell model used may introduced uncertainties in results. The present study allowed to estimate these uncertainties in the case of fast neutron power reactors and criticical mockups. The validation of new simple methods and the definition of references is a consequence of this work [fr

  14. Mutual diffusion coefficients of L-glutamic acid and monosodium L-glutamate in aqueous solutions at T = 298.15 K

    International Nuclear Information System (INIS)

    Ribeiro, Ana C.F.; Rodrigo, M.M.; Barros, Marisa C.F.; Verissimo, Luis M.P.; Romero, Carmen; Valente, Artur J.M.; Esteso, Miguel A.

    2014-01-01

    Highlights: • Interdiffusion coefficients of L-glutamic acid and sodium L-glutamate were measured. • The L-glutamic acid behaves as a monoprotic weak acid. • The sodium L-glutamate shows a symmetrical 1:1 non-associated behaviour. • Limiting diffusion coefficients and ionic conductivities were estimated. • Diffusion coefficients were discussed on the basis of the Onsager–Fuoss equations. - Abstract: Mutual diffusion coefficient values for binary aqueous solutions of both L-glutamic acid (H 2 Glu) and sodium L-glutamate (NaHGlu) were measured with the Taylor dispersion technique, at T = 298.15 K, and concentrations ranging from (0.001 to 0.100) mol · dm −3 . The results were discussed on the basis of the Onsager–Fuoss and the Nernst theoretical equations, by considering the H 2 Glu as a weak acid (monoprotic acid, with K 2 = 5.62 · 10 −5 ). The smaller values found for the acid with respect to those of the salt, confirm this association hypothesis. From the diffusion coefficient values at infinitesimal concentration, limiting ionic conductivities as well as the hydrodynamic radius of the hydrogen glutamate ion (HGlu − ) were derived and analyzed in terms of the chain methylene groups. The effect of different phenomena, such as association or complexation, were also taken into consideration and discussed. Values for the dissociation degree for H 2 Glu were also estimated

  15. Permeability estimation from NMR diffusion measurements in reservoir rocks.

    Science.gov (United States)

    Balzarini, M; Brancolini, A; Gossenberg, P

    1998-01-01

    It is well known that in restricted geometries, such as in porous media, the apparent diffusion coefficient (D) of the fluid depends on the observation time. From the time dependence of D, interesting information can be derived to characterise geometrical features of the porous media that are relevant in oil industry applications. In particular, the permeability can be related to the surface-to-volume ratio (S/V), estimated from the short time behaviour of D(t), and to the connectivity of the pore space, which is probed by the long time behaviour of D(t). The stimulated spin-echo pulse sequence, with pulsed magnetic field gradients, has been used to measure the diffusion coefficients on various homogeneous and heterogeneous sandstone samples. It is shown that the petrophysical parameters obtained by our measurements are in good agreement with those yielded by conventional laboratory techniques (gas permeability and electrical conductivity). Although the diffusing time is limited by T1, eventually preventing an observation of the real asymptotic behaviour, and the surface-to-volume ratio measured by nuclear magnetic resonance is different from the value obtained by BET because of the different length scales probed, the measurement remains reliable and low-time consuming.

  16. Diffusion weighted imaging for differentiating benign from malignant orbital tumors: Diagnostic performance of the apparent diffusion coefficient based on region of interest selection method

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Xiao Quan; Hu, Hao Hu; Su, Guo Yi; Liu, Hu; Shi, Hai Bin; Wu, Fei Yun [First Affiliated Hospital of Nanjing Medical University, Nanjing (China)

    2016-09-15

    To evaluate the differences in the apparent diffusion coefficient (ADC) measurements based on three different region of interest (ROI) selection methods, and compare their diagnostic performance in differentiating benign from malignant orbital tumors. Diffusion-weighted imaging data of sixty-four patients with orbital tumors (33 benign and 31 malignant) were retrospectively analyzed. Two readers independently measured the ADC values using three different ROIs selection methods including whole-tumor (WT), single-slice (SS), and reader-defined small sample (RDSS). The differences of ADC values (ADC-ROI{sub WT}, ADC-ROI{sub SS}, and ADC-ROI{sub RDSS}) between benign and malignant group were compared using unpaired t test. Receiver operating characteristic curve was used to determine and compare their diagnostic ability. The ADC measurement time was compared using ANOVA analysis and the measurement reproducibility was assessed using Bland-Altman method and intra-class correlation coefficient (ICC). Malignant group showed significantly lower ADC-ROI{sub WT}, ADC-ROI{sub SS}, and ADC-ROI{sub RDSS} than benign group (all p < 0.05). The areas under the curve showed no significant difference when using ADC-ROI{sub WT}, ADC-ROI{sub SS}, and ADC-ROI{sub RDSS} as differentiating index, respectively (all p > 0.05). The ROI{sub SS} and ROI{sub RDSS} required comparable measurement time (p > 0.05), while significantly shorter than ROI{sub WT} (p < 0.05). The ROI{sub SS} showed the best reproducibility (mean difference ± limits of agreement between two readers were 0.022 [-0.080–0.123] × 10{sup -3} mm{sup 2}/s; ICC, 0.997) among three ROI method. Apparent diffusion coefficient values based on the three different ROI selection methods can help to differentiate benign from malignant orbital tumors. The results of measurement time, reproducibility and diagnostic ability suggest that the ROI{sub SS} method are potentially useful for clinical practice.

  17. Estimation of diffusion coefficients in bitumen solvent mixtures as derived from low field NMR spectra

    International Nuclear Information System (INIS)

    Wen, Y.; Bryan, J.; Kantzas, A.

    2005-01-01

    Use of solvents for the extraction of heavy oil and bitumen appears to be an increasingly feasible technology. Both vapour extraction and direct solvent injection are considered for conventional exploration and production schemes, while solvent dilution of bitumen is a standard technique in oil sands mining. Mass transfer between solvent and bitumen is a poorly understood process. In some cases, it is totally ignored compared to viscous force effects. In other cases, phenomenological estimations of diffusion and dispersion coefficients are used. Low field NMR has been used successfully in determining both solvent content and viscosity reduction in heavy oil and bitumen mixtures with various solvents. As a solvent comes into contact with a heavy oil or bitumen sample, the mobility of hydrogen bearing molecules of both solvent and oil changes. These changes are detectable through changes in the NMR relaxation characteristics of both solvent and oil. Relaxation changes can then be correlated to mass flux and concentration changes. Based on Fick's Second Law, a diffusion coefficient, which is independent of concentration, was calculated against three oils and six solvents. (author)

  18. Correlation between 3 T apparent diffusion coefficient values and grading of invasive breast carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Cipolla, Valentina, E-mail: valentina.cipolla@yahoo.it [Department of Radiological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy); Santucci, Domiziana; Guerrieri, Daniele; Drudi, Francesco Maria [Department of Radiological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy); Meggiorini, Maria Letizia [Department of Gynaecological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy); Felice, Carlo de [Department of Radiological Sciences, University of Rome “Sapienza”, Viale del Policlinico 155, 00161 Rome (Italy)

    2014-12-15

    Highlights: • Apparent diffusion coefficient is a quantitative parameter which reflects molecular water movement. • Grading is an independent prognostic factor which correlates with other histopathological features. • Apparent diffusion coefficient values were significantly different between G1 and G3 classes. - Abstract: Purpose: The aim of this study was to evaluate whether the apparent diffusion coefficient (ADC) provided by 3.0 T (3 T) magnetic resonance diffusion-weighted imaging (DWI) varied according to the grading of invasive breast carcinoma. Materials and methods: A total of 92 patients with 96 invasive breast cancer lesions were enrolled; all had undergone 3 T magnetic resonance imaging (MRI) for local staging. All lesions were confirmed by histological analysis, and tumor grade was established according to the Nottingham Grading System (NGS). MRI included both dynamic contrast-enhanced and DWI sequences, and ADC value was calculated for each lesion. ADC values were compared with NGS classification using the Mann–Whitney U and the Kruskal–Wallis H tests. Grading was considered as a comprehensive prognostic factor, and Rho Spearman test was performed to determine correlation between grading and tumor size, hormonal receptor status, HER2 expression and Ki67 index. Pearson's Chi square test was carried out to compare grading with the other prognostic factors. Results: ADC values were significantly higher in G1 than in G3 tumors. No significant difference was observed when G1 and G3 were compared with G2. Tumor size, hormonal receptor status, HER2 expression and Ki67 index correlated significantly with grading but there was a significant difference only between G1 and G3 related to the ER and PR status, HER2 expression and Ki67 index. There was no statistically significant difference in lesion size between the two groups. Conclusion: ADC values obtained on 3 T DWI correlated with low-grade (G1) and high-grade (G3) invasive breast carcinoma. 3

  19. Measurements of recombination coefficient of hydrogen atoms on plasma deposited thin films

    International Nuclear Information System (INIS)

    Drenik, A.; Vesel, A.; Mozetic, M.

    2006-01-01

    We have performed experiments in plasma afterglow in order to determine the recombination coefficients of plasma deposited thin films of tungsten and graphite. Plasma deposited films rather than bulk material were used in order to more closely emulate surface structure of plasma-facing material deposits in fusion reactors. We have also determined the recombination coefficient of 85250 borosilicate glass and Teflon. Plasma was created by means of a radio frequency generator in a mixture of argon and hydrogen at the pressures between 60 Pa and 280 Pa. The degree of dissociation of hydrogen molecules was found to be between 0.1 and 1. The H-atom density was measured by Fiber Optic Catalytic Probe. The recombination coefficient was determined by measuring the axial profile of the H-atom density and using Smith's side arm diffusion model. (author)

  20. Discharge Coefficient Measurements for Flow Through Compound-Angle Conical Holes with Cross-Flow

    Directory of Open Access Journals (Sweden)

    M. E. Taslim

    2004-01-01

    Full Text Available Diffusion-shaped film holes with compound angles are currently being investigated for high temperature gas turbine airfoil film cooling. An accurate prediction of the coolant blowing rate through these film holes is essential in determining the film effectiveness. Therefore, the discharge coefficients associated with these film holes for a range of hole pressure ratios is essential in designing airfoil cooling circuits. Most of the available discharge coefficient data in open literature has been for cylindrical holes. The main objective of this experimental investigation was to measure the discharge coefficients for subsonic as well as supersonic pressure ratios through a single conical-diffusion hole. The conical hole has an exit-to-inlet area ratio of 4, a nominal flow length-to-inlet diameter ratio of 4, and an angle with respect to the exit plane (inclination angle of 0°, 30°, 45°, and 60°. Measurements were performed with and without a cross-flow. For the cases with a cross-flow, discharge coefficients were measured for each of the hole geometries and 5 angles between the projected conical hole axis and the cross-flow direction of 0°, 45°, 90°, 135°, and 180°. Results are compared with available data in open literature for cylindrical film holes as well as limited data for conical film holes.

  1. [Characteristics of high resolution diffusion weighted imaging apparent diffusion coefficient histogram and its correlations with cancer stages in patients with nasopharyngeal carcinoma].

    Science.gov (United States)

    Wang, G J; Wang, Y; Ye, Y; Chen, F; Lu, Y T; Li, S L

    2017-11-07

    Objective: To investigate the features of apparent diffusion coefficient (ADC) histogram parameters based on entire tumor volume data in high resolution diffusion weighted imaging of nasopharyngeal carcinoma (NPC) and to evaluate its correlations with cancer stages. Methods: This retrospective study included 154 cases of NPC patients[102 males and 52 females, mean age (48±11) years]who had received readout segmentation of long variable echo trains of MRI scan before radiation therapy. The area of tumor was delineated on each section of axial ADC maps to generate ADC histogram by using Image J. ADC histogram of entire tumor along with the histogram parameters-the tumor voxels, ADC(mean), ADC(25%), ADC(50%), ADC(75%), skewness and kurtosis were obtained by merging all sections with SPSS 22.0 software. Intra-observer repeatability was assessed by using intra-class correlation coefficients (ICC). The patients were subdivided into two groups according to cancer volume: small cancer group (histogram parameters and cancer stages was evaluated with Spearman test. Results: The ICC of measuring ADC histogram parameters of tumor voxels, ADC(mean), ADC(25%), ADC(50%), ADC(75%), skewness, kurtosis was 0.938, 0.861, 0.885, 0.838, 0.836, 0.358 and 0.456, respectively. The tumor voxels was positively correlated with T staging ( r =0.368, P histogram (ADC(mean), ADC(25%), ADC(50%)) increases with T staging in NPC smaller than 2 cm(3).

  2. Experimental Determination of Impurity and Interdiffusion Coefficients in Seven Ti and Zr Binary Systems Using Diffusion Multiples

    Science.gov (United States)

    Chen, Zhangqi; Liu, Zi-Kui; Zhao, Ji-Cheng

    2018-05-01

    Diffusion coefficients of seven binary systems (Ti-Mo, Ti-Nb, Ti-Ta, Ti-Zr, Zr-Mo, Zr-Nb, and Zr-Ta) at 1200 °C, 1000 °C, and 800 °C were experimentally determined using three Ti-Mo-Nb-Ta-Zr diffusion multiples. Electron probe microanalysis (EPMA) was performed to collect concentration profiles at the binary diffusion regions. Forward simulation analysis (FSA) was then applied to extract both impurity and interdiffusion coefficients in Ti-rich and Zr-rich part of the bcc phase. Excellent agreements between our results and most of the literature data validate the high-throughput approach combining FSA with diffusion multiples to obtain a large amount of systematic diffusion data, which will help establish the diffusion (mobility) databases for the design and development of biomedical and structural Ti alloys.

  3. Local, zero-power void coefficient measurements in the ACPR

    Energy Technology Data Exchange (ETDEWEB)

    Rivard, J B; Thome, F V [Sandia Laboratories (United States)

    1974-07-01

    Changes in reactivity may be stimulated in the ACPR by the local introduction of voids into the reactor coolant. The local void coefficients of reactivity which describe this effect are of interest from a reactor safety point-of-view, and their determination is the subject of this presentation. Bottled nitrogen gas was used to produce the voids. The gas was forced out of a small diameter tube which was positioned vertically in the core lattice with its open end below the fuel. The gas was passed through a pressure regulator, a valve, and a flowmeter to establish a steady flow condition, following which a delayed-critical (zero-power) reactor state was established. Correlation of the average volume of core void created by the nitrogen flow with the reactivity worth of the delayed-critical control-rod bank position produced the values of the zero-power void coefficients of reactivity. The void coefficients were determined at various core positions from {approx}6 mm to 142 mm beyond the central irradiation space and for three different flow rates. For the range of void fractions investigated, these coefficients are negative, with values ranging between -$0.02 and -$0.12. Tabular and graphical results of the measurements are presented, and details of the coefficient determination are explained. (author)

  4. Local, zero-power void coefficient measurements in the ACPR

    International Nuclear Information System (INIS)

    Rivard, J.B.; Thome, F.V.

    1974-01-01

    Changes in reactivity may be stimulated in the ACPR by the local introduction of voids into the reactor coolant. The local void coefficients of reactivity which describe this effect are of interest from a reactor safety point-of-view, and their determination is the subject of this presentation. Bottled nitrogen gas was used to produce the voids. The gas was forced out of a small diameter tube which was positioned vertically in the core lattice with its open end below the fuel. The gas was passed through a pressure regulator, a valve, and a flowmeter to establish a steady flow condition, following which a delayed-critical (zero-power) reactor state was established. Correlation of the average volume of core void created by the nitrogen flow with the reactivity worth of the delayed-critical control-rod bank position produced the values of the zero-power void coefficients of reactivity. The void coefficients were determined at various core positions from ∼6 mm to 142 mm beyond the central irradiation space and for three different flow rates. For the range of void fractions investigated, these coefficients are negative, with values ranging between -$0.02 and -$0.12. Tabular and graphical results of the measurements are presented, and details of the coefficient determination are explained. (author)

  5. Apparent diffusion coefficient values of the normal uterus: Interindividual variations during menstrual cycle

    International Nuclear Information System (INIS)

    Tsili, A.C.; Argyropoulou, M.I.; Tzarouchi, L.; Dalkalitsis, N.; Koliopoulos, G.; Paraskevaidis, E.; Tsampoulas, K.

    2012-01-01

    Objectives: To assess the apparent diffusion coefficient (ADC) changes of the normal uterine zones among reproductive women during the menstrual cycle. Methods: The study included 101 women of reproductive age, each with regular cycle and normal endometrium/myometrium, as proved on histopathology or MR imaging examination. Diffusion-weighted (DW) imaging was performed along the axial plane, using a single shot, multi-slice spin-echo planar diffusion pulse sequence and b-values of 0 and 800 s/mm 2 . The mean and standard deviation of the ADC values of normal endometrium/myometrium were calculated for menstrual, proliferative and secretory phase. Analysis of variance followed by the least significant difference test was used for statistical analysis. Results: The ADC values of the endometrium were different in the three phases of the menstrual cycle (menstrual phase: 1.25 ± 0.27; proliferative phase: 1.39 ± 0.20; secretory phase: 1.50 ± 0.18) (F: 9.64, p: 0.00). Statistical significant difference was observed among all groups (p 0.05). Conclusions: A wide variation of ADC values of normal endometrium and myometrium is observed during different phases of the menstrual cycle.

  6. Relationship between apparent diffusion coefficients at 3.0-T MR imaging and Gleason grade in peripheral zone prostate cancer

    NARCIS (Netherlands)

    Hambrock, T.; Somford, D.M.; Huisman, H.J.; Oort, I.M. van; Witjes, J.A.; Hulsbergen-van de Kaa, C.A.; Scheenen, T.W.J.; Barentsz, J.O.

    2011-01-01

    PURPOSE: To retrospectively determine the relationship between apparent diffusion coefficients (ADCs) obtained with 3.0-T diffusion-weighted (DW) magnetic resonance (MR) imaging and Gleason grades in peripheral zone prostate cancer. MATERIALS AND METHODS: The requirement to obtain institutional

  7. A technique for measuring dynamic friction coefficient under impact loading.

    Science.gov (United States)

    Lin, Y L; Qin, J G; Chen, R; Zhao, P D; Lu, F Y

    2014-09-01

    We develop a novel setup based on the split Hopkinson pressure bar technique to test the dynamic friction coefficient under impact loading. In the setup, the major improvement is that the end of the incident bar near the specimen is wedge-shaped, which results in a combined compressive and shear loading applied to the specimen. In fact, the shear loading is caused by the interfacial friction between specimen and bars. Therefore, when the two loading force histories are measured, the friction coefficient histories can be calculated without any assumptions and theoretical derivations. The geometry of the friction pairs is simple, and can be either cuboid or cylindrical. Regarding the measurements, two quartz transducers are used to directly record the force histories, and an optical apparatus is designed to test the interfacial slip movement. By using the setup, the dynamic friction coefficient of PTFE/aluminum 7075 friction pairs was tested. The time resolved dynamic friction coefficient and slip movement histories were achieved. The results show that the friction coefficient changes during the loading process, the average data of the relatively stable flat plateau section of the friction coefficient curves is 0.137, the maximum normal pressure is 52 MPa, the maximum relative slip velocity is 1.5 m/s, and the acceleration is 8400 m(2)/s. Furthermore, the friction test was simulated using an explicit FEM code LS-DYNA. The simulation results showed that the constant pressure and slip velocity can both be obtained with a wide flat plateau incident pulse. For some special friction pairs, normal pressure up to a few hundred MPa, interfacial slip velocities up to 10 m/s, and slip movement up to centimeter-level can be expected.

  8. Measurements of the Drag Coefficient of Simulated Micrometeoroids

    Science.gov (United States)

    DeLuca, M.; Munsat, T.; Sternovsky, Z.

    2017-12-01

    The dust accelerator facility operated at the University of Colorado is used to simulate meteoric ablation, including measuring the ionization efficiency over a wide range of velocities (e.g., DeLuca et al., Planet. Space Sci., submitted, 2017). This presentation reports on the most recent experimental measurements of the drag coefficient that determines the particles' slowdown from their frictional interaction with the atmosphere. The measurements indicate that meteors experience considerably more slowdown than usually assumed. The simulated meteors consisted of submicron sized aluminum particles shot into an air chamber held at 200 mTorr pressure at velocities between 1 - 10 km/s using the dust accelerator and meteor ablation facility. The slowdown is calculated from precise timing measurements made using pickup tube detectors placed upstream and near the entrance to the air chamber, and an impact detector inside the air chamber at the downstream end of the chamber. Supporting modeling calculations show that the particles have little or no mass loss during their interaction with air and thus constant radius can be assumed. Preliminary results for the drag coefficient calculated from these timing measurements reveal that the aluminum particles have a drag coefficient of 1.51 ± 0.24 in air, which is higher than typically assumed in meteoric ablation models (usually 0.5 to 1), indicating that meteors may experience more air drag than previously assumed. More detailed measurements over a wider parameter range are underway.

  9. First-principles calculations of impurity diffusion coefficients in dilute Mg alloys using the 8-frequency model

    International Nuclear Information System (INIS)

    Ganeshan, S.; Hector, L.G.; Liu, Z.-K.

    2011-01-01

    Research highlights: → Implemented the eight frequency model for impurity diffusion in hexagonal metals. → Model inputs were energetics/vibrational properties from first princples. → Predicted diffusion coefficients for Al, Ca, Zn and Sn impurity diffusion in Mg. → Successful prediction of partial correlation factors and jump frequencies. → Good agreement between calculated and experimental results. - Abstract: Diffusion in dilute Mg-X alloys, where X denotes Al, Zn, Sn and Ca impurities, was investigated with first-principles density functional theory in the local density approximation. Impurity diffusion coefficients were computed as a function of temperature using the 8-frequency model which provided the relevant impurity and solvent (Mg) jump frequencies and correlation factors. Minimum energy pathways for impurity diffusion and associated saddle point structures were computed with the climbing image nudged elastic band method. Vibrational properties were obtained with the supercell (direct) method for lattice dynamics. Calculated diffusion coefficients were compared with available experimental data. For diffusion between basal planes, we find D Mg-Ca > D Mg-Zn > D Mg-Sn > D Mg-Al, where D is the diffusion coefficient. For diffusion within a basal plane, the same trend holds except that D Mg-Zn overlaps with D Mg-Al at high temperatures and D Mg-Sn at low temperatures. These trends were explored with charge density contours in selected planes of each Mg-X alloy, the variation of the activation energy for diffusion with the atomic radius of each impurity and the electronic density of states. The theoretical methodology developed herein can be applied to impurity diffusion in other hexagonal materials.

  10. Anisotropy in "isotropic diffusion" measurements due to nongaussian diffusion

    DEFF Research Database (Denmark)

    Jespersen, Sune Nørhøj; Olesen, Jonas Lynge; Ianuş, Andrada

    2017-01-01

    Designing novel diffusion-weighted NMR and MRI pulse sequences aiming to probe tissue microstructure with techniques extending beyond the conventional Stejskal-Tanner family is currently of broad interest. One such technique, multidimensional diffusion MRI, has been recently proposed to afford...... model-free decomposition of diffusion signal kurtosis into terms originating from either ensemble variance of isotropic diffusivity or microscopic diffusion anisotropy. This ability rests on the assumption that diffusion can be described as a sum of multiple Gaussian compartments, but this is often...

  11. Mass transfer of SCWO processes: Molecular diffusion and mass transfer coefficients of inorganic nitrate species in sub- and supercritical water

    Energy Technology Data Exchange (ETDEWEB)

    Goemans, M.G.E.; Gloyna, E.F. [Univ. of Texas, Austin, TX (United States). Dept. of Civil Engineering; Buelow, S.J. [Los Alamos National Lab., NM (United States)

    1996-04-01

    Molecular diffusion coefficients of lithium-, sodium-, potassium-, cesium-, calcium-, and strontium nitrate in subcritical water were determined