WorldWideScience

Sample records for diagnostic techniques

  1. Diagnostic techniques

    International Nuclear Information System (INIS)

    Berquist, T.H.; Bender, C.E.; James, E.M.; Brown, M.L.; McLeod, R.A.; Broderick, D.F.; Welch, T.J.

    1989-01-01

    Proper application of imaging procedures is essential to obtain needed information for diagnosis and therapy planning in patients with suspected foot and/or ankle pathology. This paper provides basic background data for the numerous imaging techniques

  2. Novel Nonlinear Laser Diagnostic Techniques

    Science.gov (United States)

    1993-07-01

    a thermometric probe of reactive flows. Since the two-photon pump laser couples a Doppler broadened ground state velocity distribution to the excited...rism, and passed unfocused into an aluminum cell con- in frequency space. Regions for line fitting are found by taining 99% pure NO. The gas mixture...of ASE as a More recently, ASE has prompted interest as an thermometric probe of combustion environments optical diagnostic of combustion environments

  3. Mammography: Technique and diagnostic accuracy

    International Nuclear Information System (INIS)

    Kim, Chung Ja; Bahk, Yong Whee; Lee, Don Young

    1974-01-01

    Mammography is now in world wide use, But this has received rather scanty attention in Korea. The purposes of the present communication are twofold: (1) Detailing of technical and photographic aspects of mam in ography and (2) an assessment of its diagnostic accuracy as experienced by us. The clinical materials consisted of 88 cases of mammography performed at the Department of Radiology, St. Mary's Hospital, Catholic Medical College during the 2 years-period from April 1972. We used nonscreen type mammographic or industrial fine- grain films, and a special mammographic device that can be attached to any of the ordinary radiographic machine. Technical factors are shown in Table II. Of 88 cases 19 were operated on or biopsied. There were 7 cases of carcinoma. 8 cases of inflammatory diseases, and 4 cases of benign tumor. Mammographic diagnosis was correct in 85.7% of carcinoma and 87.5% of inflammatory diseases. One misdiagnosis of 7 cases of carcinoma was turned out to be cystosarcoma phylloides. Of 4 cases of benign tumors 2 were correctly diagnosed, and the other 2 mistaken for either inflammatory disease or simple lactating breast. However, none of the benign conditions were diagnosed as malignant process. We found that nonscreen type mammographic or industrial fine-grain films, and hand-processing were necessary in obtaining the mammograms of desirable quality

  4. Progress in diagnostic techniques for sc cavities

    International Nuclear Information System (INIS)

    Reece, C.E.

    1988-01-01

    While routinely achieved performance characteristics of superconducting cavities have now reached a level which makes them useful in large scale applications, achieving this level has come only through the knowledge gained by systematic studies of performance limiting phenomena. Despite the very real progress that has been made, the routine performance of superconducting cavities still falls far short of both the theoretical expectations and the performance of a few exception examples. It is the task of systematically applied diagnostic techniques to reveal additional information concerning the response of superconducting surfaces to applied RF fields. Here recent developments in diagnostic techniques are discussed. 18 references, 12 figures

  5. Alternative diagnostic technique for carpal tunnel syndrome

    International Nuclear Information System (INIS)

    Hayakawa, Katsuhiko; Nakane, Takashi; Kobayashi, Shigeru; Shibata, Kunio

    2002-01-01

    Compressive and entrapment neuropathies are common clinical syndromes characterized by neurologic deficits due to mechanical or dynamic compression of peripheral nerves. However, the definitive diagnosis based on clinical symptoms alone is difficult in many cases, and the electrophysiological diagnostic method is solely used as a supplementary diagnostic method at present. As a new diagnostic method for entrapment neuropathy, the present study investigated the usefulness of gadolinium-enhanced MRI in carpal tunnel syndrome. On enhanced MRI of idiopathic carpal tunnel syndrome, contrast-enhancement in the median nerve was found in 30 of 34 hands (88.2%). Enhanced MRI allows to visualize intraneural edema in the nerve easily on the naked eye. Therefore, this technique supplied useful information for making definitive diagnosis and is promising as a non-invasive diagnostic method for entrapment neuropathy. (author)

  6. Alternative diagnostic technique for carpal tunnel syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Hayakawa, Katsuhiko; Nakane, Takashi [Aiko Orthopaedic Hospital, Nagoya (Japan); Kobayashi, Shigeru; Shibata, Kunio [Fujita Health Univ., Toyoake, Aichi (Japan). School of Medicine

    2002-10-01

    Compressive and entrapment neuropathies are common clinical syndromes characterized by neurologic deficits due to mechanical or dynamic compression of peripheral nerves. However, the definitive diagnosis based on clinical symptoms alone is difficult in many cases, and the electrophysiological diagnostic method is solely used as a supplementary diagnostic method at present. As a new diagnostic method for entrapment neuropathy, the present study investigated the usefulness of gadolinium-enhanced MRI in carpal tunnel syndrome. On enhanced MRI of idiopathic carpal tunnel syndrome, contrast-enhancement in the median nerve was found in 30 of 34 hands (88.2%). Enhanced MRI allows to visualize intraneural edema in the nerve easily on the naked eye. Therefore, this technique supplied useful information for making definitive diagnosis and is promising as a non-invasive diagnostic method for entrapment neuropathy. (author)

  7. A REVIEW ON DIAGNOSTIC TECHNIQUES FOR BRUCELLOSIS

    African Journals Online (AJOL)

    User

    2014-01-01

    Jan 1, 2014 ... Brucellosis presents with many clinical manifestation that make its diagnosis a difficult task. Ever since the report of the first serologic test for brucellosis, a definitive diagnostic technique has been actively pursued. The most widely used methods of diagnosis are based on serology, which measures the.

  8. Adaptive techniques for diagnostics of vibrating structures

    International Nuclear Information System (INIS)

    Skormin, V.A.; Sankar, S.

    1983-01-01

    An adaptive diagnostic procedure for vibrating structures based on correspondence between current estimates of stiffness matrix and structure status is proposed. Procedure employs adaptive mathematical description of the vibrating structure in frequency domain, statistical techniques for detection and location of changes of structure properties, 'recognition' and prediction of defects. (orig.)

  9. Technique of infrared synchrotron acceleration diagnostics

    International Nuclear Information System (INIS)

    Mal'tsev, A.A.; Mal'tsev, M.A.

    1997-01-01

    Techniques of measuring of current and geometric parameters and evaluating of energy parameters of the ring bunch of relativistic low-energy electrons have been presented. They have been based on using the synchrotron radiation effect in its infrared spectral part. Fast infrared detectors have provided radiation detection in the spectral range Δλ ≅ 0.3-45 μm. The descriptions of some data monitoring and measuring systems developed in JINR for the realization of techniques of the infrared synchrotron acceleration diagnostics have been given. Infrared optics elements specially developed have been used in these systems

  10. Dental diagnostics using optical coherence techniques

    Energy Technology Data Exchange (ETDEWEB)

    Nathel, H. [Lawrence Livermore National Lab., CA (United States); Colston, B. [Univ. of California, San Francisco, CA (United States); Armitage, G. [Univ. of California, Davis, CA (United States)] [and others

    1994-11-15

    Optical radiation can be used for diagnostic purposes in oral medicine. However, due to the turbid, amorphous, and inhomogeneous nature of dental tissue conventional techniques used to transilluminate materials are not well suited to dental tissues. Optical coherence techniques either in the time- of frequency-domain offer the capabilities of discriminating scattered from unscattered light, thus allowing for imaging through turbid tissue. Currently, using optical time-domain reflectometry we are able to discriminate specular from diffuse reflections occurring at tissue boundaries. We have determined the specular reflectivity of enamel and dentin to be approximately 6.6 x 10{sup -5} and 1.3 x 10{sup -6}, respectively. Implications to periodontal imaging will be discussed.

  11. Noninvasive Diagnostic Technique in Stenotic Coronary Atherosclerosis

    Directory of Open Access Journals (Sweden)

    A. Yu. Vasilyev

    2005-01-01

    Full Text Available Objective: to determine the sensitivity and specificity of combined stress echocardiography (EchoCG using dipyri-damole and dobutamine in diagnosing and defining the extent of stenotic coronary lesions in coronary heart disease (CHD in a group of critically ill patients who are unable to perform a physical exercise.Materials and methods: the study included 57 male patients with suspected acute coronary syndrome who underwent stress EchoCG using dipyridamole in high doses in combination with dobutamine, as well as coronary angiography.Results: stress EchoCG could bring up to the diagnostic criteria in all the patients, of whom 9 patients were found at coronary angiography to have no coronary lesion, 34 and 14 patients had one- and many-vessel lesions, respectively. The sensitivity and specificity of combined stress EchoCG were significantly higher than those of EchoCG used in the diagnosis of CHD.Conclusion: stress EchoCG using dipyridamole in combination with dobutamine is a highly informative safe noninvasive technique for diagnosing CHD, its helps to identify patients with atypical acute coronary syndrome and to form a group of patients to be subject to urgent coronarography and angiosurgical intervention. The pattern of segmental contractile disorders at the height of exercise during combined stress Echo-CG makes it possible to define the site of stenotic coronary atherosclerosis with 97.3% sensitivity and to diagnose many-vessel lesion with 100% sensitivity and 100%specificity.

  12. Noise diagnostic: An advanced technique in Cuba

    International Nuclear Information System (INIS)

    Aguilar, O.

    1992-01-01

    This paper examines the main steps of the noise analysis technique implementation in our country from 1988. The review identifies two main areas, improvements of Nuclear Power Plant operational surveillance techniques and non-nuclear industrial applications. Also reported are some of the on going researches programs including projects on noise analysis instrumentation developments at the Higher Institute for Nuclear Sciences and Technology

  13. The Awareness of Health Professionals in Diagnostic Techniques ...

    African Journals Online (AJOL)

    hanumantp

    clear that most reviewed articles used the same conventional methods in ... Knowledge about the possible correlation of occult blood with reasons other than ... diagnostic techniques used in the examination of intestinal parasites in Gaza Strip.

  14. [Advances of Molecular Diagnostic Techniques Application in Clinical Diagnosis.

    Science.gov (United States)

    Ying, Bin-Wu

    2016-11-01

    Over the past 20 years,clinical molecular diagnostic technology has made rapid development,and became the most promising field in clinical laboratory medicine.In particular,with the development of genomics,clinical molecular diagnostic methods will reveal the nature of clinical diseases in a deeper level,thus guiding the clinical diagnosis and treatments.Many molecular diagnostic projects have been routinely applied in clinical works.This paper reviews the advances on application of clinical diagnostic techniques in infectious disease,tumor and genetic disorders,including nucleic acid amplification,biochip,next-generation sequencing,and automation molecular system,and so on.

  15. Essentials of diagnostic and interventional angiographic technique

    International Nuclear Information System (INIS)

    Gerlock, A.J.; Mirfakhraee, M.

    1985-01-01

    This volume presents coverage of basic angiographic techniques and shows how to get to the point of taking the angiogram, and tells how to avoid pitfalls. Particularly valuable is the information on how to get out of trouble if an error is made while manipulating the catheter

  16. Noninvasive Remote Sensing Techniques for Infrastructures Diagnostics

    Directory of Open Access Journals (Sweden)

    Angelo Palombo

    2011-01-01

    Full Text Available The present paper aims at analyzing the potentialities of noninvasive remote sensing techniques used for detecting the conservation status of infrastructures. The applied remote sensing techniques are ground-based microwave radar interferometer and InfraRed Thermography (IRT to study a particular structure planned and made in the framework of the ISTIMES project (funded by the European Commission in the frame of a joint Call “ICT and Security” of the Seventh Framework Programme. To exploit the effectiveness of the high-resolution remote sensing techniques applied we will use the high-frequency thermal camera to measure the structures oscillations by high-frequency analysis and ground-based microwave radar interferometer to measure the dynamic displacement of several points belonging to a large structure. The paper describes the preliminary research results and discusses on the future applicability and techniques developments for integrating high-frequency time series data of the thermal imagery and ground-based microwave radar interferometer data.

  17. Diagnostic techniques in deflagration and detonation studies.

    Science.gov (United States)

    Proud, William G; Williamson, David M; Field, John E; Walley, Stephen M

    2015-12-01

    Advances in experimental, high-speed techniques can be used to explore the processes occurring within energetic materials. This review describes techniques used to study a wide range of processes: hot-spot formation, ignition thresholds, deflagration, sensitivity and finally the detonation process. As this is a wide field the focus will be on small-scale experiments and quantitative studies. It is important that such studies are linked to predictive models, which inform the experimental design process. The stimuli range includes, thermal ignition, drop-weight, Hopkinson Bar and Plate Impact studies. Studies made with inert simulants are also included as these are important in differentiating between reactive response and purely mechanical behaviour.

  18. Mechanical system diagnostics using vibration testing techniques

    Science.gov (United States)

    Mcleod, Catherine D.; Raju, P. K.; Crocker, M. J.

    1990-01-01

    The 'Cepstrum' technique of vibration-path identification allows the recovery of the transfer function of a system with little knowledge as to its excitation force, by means of a mathematical manipulation of the system output in conjunction with subtraction of part of the output and suitable signal processing. An experimental program has been conducted to evaluate the usefulness of this technique in the cases of simple, cantilever-beam and free-free plate structures as well as in that of a complex mechanical system. On the basis of the transfer functions thus recovered, it was possible to evaluate the shifts in the resonance frequencies of a structure due to the presence of defects.

  19. Diagnostic techniques in cerebral artery occlusions

    Energy Technology Data Exchange (ETDEWEB)

    Huber, P

    1972-01-01

    In two-thrids of the cases of cerebral artery occlusions ophthalmodynamotry, thermography, and the fluorescein test are sufficient. In cases where these give insufficient data, scintigraphy is the preferred screening method. For determination of the regional blood flow /sup 133/Xe is used. Angiographic investigation, however, is the method that gives the most clinically valuable data. The techniques used and the risks inherent in the method are described. (JSR)

  20. Oncologic applications of diagnostic imaging techniques

    International Nuclear Information System (INIS)

    Forrest, L.J.; Thrall, D.E.

    1995-01-01

    Before appropriate therapy can be instituted for a cancer patient, the presence and extent of tumor must be evaluated. Deciding which imaging technique to use depends on tumor location, type, and biologic behavior. Conventional radiography provides important information at a relatively low cost compared with other imaging modalities. Ultrasound is a valuable adjunct to radiography, but does not replace it because both imaging modalities provide unique information. Nuclear medicine procedures contribute additional, unique data by providing physiological information, but specificity is lacking. Both CT and MRI provide images with exquisite anatomic detail, but availability and cost prohibit their general use

  1. Some novel diagnostic techniques for plasma chemistry

    International Nuclear Information System (INIS)

    Kaufman, M.

    1976-01-01

    In order to probe the mechanisms of chemical transformations in electric discharges it is most useful to monitor concentrations of reactants, products and reactive intermediates as a function of discharge parameters. Mass spectrometry, a popular technique for observing intermediates in chemical reactions, meets with particular difficulty when applied to discharges, due to the presence of excited molecules as well as free radicals in such systems. Molecular beam analysis, a synthesis of mass spectrometry with molecular beam measurements of electric and magnetic moments and velocity distributions, is a technique developed in the laboratory which offers distinct advantages for the analysis of intermediates in electric discharges. In low pressure discharges, end-product analysis can be facilitated by sample compression. A chromatographic sampling system which employs compression in order to achieve sensitivity has been developed and evaluated. There is some question concerning the appropriate discharge parameters to be employed in correlating measured variations in concentrations. An investigation is being made of the use of discharge 'actinometers' as a means of measuring the intensity of electric discharges. In discharges the intensity (number and energy of the electrons) and the chemistry are strongly coupled. Thus, it is necessary that the actinometer be present in the reactor; it is not permissible to substitute vessels as is customary in photochemical investigations. Since the actinometer is to measure only the discharge intensity, it must not participate in any chemical reactions with molecules and intermediates in the discharge. Finally, the ratio of the rates of the primary interactions of the actinometer and reactant with the discharge must be independent of discharge parameters. (author)

  2. Medical X-ray techniques in diagnostic radiography. 4. ed.

    International Nuclear Information System (INIS)

    Plaats, G.J. van der; Vijlbrief, P.

    1980-01-01

    A step by step account is given of every aspect of the technical factors involved in the production of X-ray images. Chapter titles include, methods of image formation and laws of projection, sharpness and unsharpness, contrast, perceptibility of detail in the radiographic image-image quality, properties of fluoroscopic screens, radiographic films, intensifying screens and cassettes, image intensification and X-ray television, processing technique, fluoroscopy and radiographic technique in general, special radiographic techniques, radiographic examinations using contrast media, exposure and exposure tables and automatic density control, diagnostic X-ray apparatus, and diagnostic stands and accessories. (C.F.)

  3. The Positron Emission Tomography. A diagnostic technique

    International Nuclear Information System (INIS)

    Salvadori, P.

    2001-01-01

    Positron Emission Tomography (PET) is a new imaging modality, which is able to assess non-invasively the biochemical mechanisms, underlying physiological and pathophysiological processes in vivo in humans. The technique relies on the administration of radioactive tracers labeled with short-lived positron emitters, which need to be produced on site via a particle accelerator (cyclotron). Radionuclides are produced upon request and formulated into biologically active organic molecules having precise pharmacokinetics and specificity. The radiotracer can be detected by the PET scanner and represented as tomographic sections (images of body sections) showing its regional distribution and concentration. This makes it possible to address clinical questions concerning occurrence and evolution of many diseases as well as their response to therapy. The ability to image (measure) biological processes and not only anatomy enables PET to explore diseases in the very early stage, including those diseases which are not related to modifications of organ structure (e.g. psychiatric diseases, metabolic disorders, biochemical disfunction). PET plays a major role, in conjunction with the other imaging modalities, to improve diagnosis capabilities and disease mechanism understanding [it

  4. Laser-based techniques for combustion diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Georgiev, N.

    1997-04-01

    Two-photon-induced Degenerate Four-Wave Mixing, DFWM, was applied for the first time to the detection of CO, and NH{sub 3} molecules. Measurements were performed in a cell, and in atmospheric-pressure flames. In the cell measurements, the signal dependence on the pressure and on the laser beam intensity was studied. The possibility of simultaneous detection of NH{sub 3} and OH was investigated. Carbon monoxide and ammonia were also detected employing two-photon-induced Polarization Spectroscopy, PS. In the measurements performed in a cold gas flow, the signal strength dependence on the laser intensity, and on the polarization of the pump beam, was investigated. An approach to improve the spatial resolution of the Amplified Stimulated Emission, ASE, was developed. In this approach, two laser beams at different frequencies were crossed in the sample. If the sum of the frequencies of the two laser beams matches a two photon resonance of the investigated species, only the molecules in the intersection volume will be excited. NH{sub 3} molecules and C atoms were studied. The potential of using two-photon LIF for two-dimensional imaging of combustion species was investigated. Although LIF is species specific, several species can be detected simultaneously by utilizing spectral coincidences. Combining one- and two-photon process, OH, NO, and O were detected simultaneously, as well as OH, NO, and NH{sub 3}. Collisional quenching is the major source of uncertainty in quantitative applications of LIF. A technique for two-dimensional, absolute species concentration measurements, circumventing the problems associated with collisional quenching, was developed. By applying simple mathematics to the ratio of two LIF signals generated from two counterpropagating laser beams, the absolute species concentration could be obtained. 41 refs

  5. Development of process diagnostic techniques for piping and equipment

    International Nuclear Information System (INIS)

    Yotsutsuji, Mitoshi

    1987-01-01

    The thing required for using the facilities composing a plant for a long period without anxiety is to quantitatively grasp the quantities of the present condition of the facilities and to take the necessary measures beforehand. For this purpose, the diagnostic techniques for quickly and accurately detect the quantities of the condition of facilities are necessary, and the development of process diagnostic techniques has been desired. The process diagnostic techniques mentioned here mean those for diagnosing the contamination, clogging and performance of towers, tanks, heat exchangers and others. Idemitsu Engineering Co. had developed a simplified diagnostic equipment for detecting the state of fouling in piping in 1982, which is the gamma ray transmission diagnosis named Scale Checker. By further improving it, the process diagnostic techniques for piping and equipment were developed. In this report, the course of development and examination, the principle of detection, the constitution and the examination of remodeling of the Scale Checker are reported. As the cases of process diagnosis in plant facilities, the diagnosis of the clogging in process piping and the diagnosis of the performance of a distillation tower were carried out. The contents of the diagnosis and the results of those cases are explained. (Kako, I.)

  6. Effectiveness of relaxation techniques before diagnostic screening of cancer patients

    Directory of Open Access Journals (Sweden)

    Montserrat Aiger

    2016-07-01

    Full Text Available Psychophysiological arousal was observed in cancer patients during the application of relaxation techniques prior to a diagnostic scan (PET-CT. The aim of the study is twofold: firstly, it is sought to establish whether such techniques can minimize patient arousal before diagnostic screening begins, and secondly to measure which of them are most effective. The dependent variable is electrodermal activity, recording the attentional level and emotional response, and the independent variable comprises the relaxation techniques used, namely Jacobson, breathing and visualization. The 39 patients were split into experimental groups to whom the relaxation techniques (Jacobson, breathing exercises, and visualization were applied before they went for the PET-CT. An activity-module procedure was applied to track electrodermal activity during the relaxation sessions, consisting of instructions, timeout; wait, task; relaxation and end of the recording session. The control group received no relaxation techniques before the PET-CT. Session-end results show that patients who perform relaxation techniques achieve greater attentional focus using Jacobson's technique (M = .212 and enhanced emotional containment using visualization (M = .206. It is concluded that relaxation techniques minimize the state of activation during the waiting period before a diagnostic scan.

  7. Electroencephalography as a diagnostic technique for canine neurological diseases

    Directory of Open Access Journals (Sweden)

    Wrzosek Marcin

    2016-06-01

    Full Text Available Electroencephalography (EEG is a non-invasive examination method for the assessment of functional central nervous system (CNS disturbances. In human medicine it has a special importance as a diagnostic tool for epilepsy. Although many studies were done on the use of EEG for diagnostics of canine central nervous system disorders, the technique is still not applied routinely. The purpose of this paper was to review the use of the electroencephalography in canine neurological disorders of central nervous system diagnosis and assess the future perspectives of this technique in veterinary medicine.

  8. Three dimensional imaging technique for laser-plasma diagnostics

    International Nuclear Information System (INIS)

    Jiang Shaoen; Zheng Zhijian; Liu Zhongli

    2001-01-01

    A CT technique for laser-plasma diagnostic and a three-dimensional (3D) image reconstruction program (CT3D) have been developed. The 3D images of the laser-plasma are reconstructed by using a multiplication algebraic reconstruction technique (MART) from five pinhole camera images obtained along different sight directions. The technique has been used to measure the three-dimensional distribution of X-ray of laser-plasma experiments in Xingguang II device, and the good results are obtained. This shows that a CT technique can be applied to ICF experiments

  9. Three dimensional imaging technique for laser-plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Shaoen, Jiang; Zhijian, Zheng; Zhongli, Liu [China Academy of Engineering Physics, Chengdu (China)

    2001-04-01

    A CT technique for laser-plasma diagnostic and a three-dimensional (3D) image reconstruction program (CT3D) have been developed. The 3D images of the laser-plasma are reconstructed by using a multiplication algebraic reconstruction technique (MART) from five pinhole camera images obtained along different sight directions. The technique has been used to measure the three-dimensional distribution of X-ray of laser-plasma experiments in Xingguang II device, and the good results are obtained. This shows that a CT technique can be applied to ICF experiments.

  10. A new techniques in the physics of diagnostic radiology

    International Nuclear Information System (INIS)

    Jennings, R.J.

    1987-01-01

    The basic physics involved in the generation of X-rays and in the energy dependence of their interaction with matter are reviewed. Some applications of those ideas in both conventional X-ray imaging and in new imaging techniques are studied. Methods for the optimization of X-ray diagnostic imaging system are discussed. (M.A.C.) [pt

  11. Diagnostic techniques used in controlled thermonuclear research at Harwell

    Energy Technology Data Exchange (ETDEWEB)

    Harding, G N; Dellis, A N; Gibson, A; Jones, B; Lees, D J; McWhirter, R W.P.; Ramsden, S A; Ward, S [UK Atomic Energy Authority, AERE, Harwell (United Kingdom)

    1958-07-01

    This paper is a general survey of the lines along which diagnostic methods (spectroscopy, electrical measurements, and the study of high energy radiations) are developing at Harwell, and indicates the results which have been obtained so far. Many of the techniques are in a rudimentary state, and most of the Zeta experiments are incomplete.

  12. Imaging nuclear medicine techniques for diagnostic evaluation of arterial hypertension

    International Nuclear Information System (INIS)

    Eisenberg, B.M.; Linss, G.

    1989-01-01

    Arterial hypertension may be caused by a malfunction of organs and in turn may lead to secondary organic lesions. Modern diagnostic nuclear medicine is applied for function studies in order to detect or exclude secondary hypertension and functional or perfusion disturbances due to hypertension, or to assess and follow up hemodynamic conditions and cardiac functions prior to and during therapy. The article presents a survey of imaging diagnostic nuclear medicine techniques for the eamination of the heart, the brain, the kidneys and endocrine glands in patients with arterial hypertension, discussing the methods with a view to obtainable information, limits of detection, and indications. (orig.) [de

  13. Progress in diagnostic techniques for SC [superconducting] cavities

    International Nuclear Information System (INIS)

    Reece, C.E.

    1988-01-01

    Despite the very real progress that has been made, the routine performance of superconducting cavities still falls far short of both the theoretical expectations and the performance of afew exceptional examples. It is the task of systematically applied diagnostic techniques to reveal additional information concerning the response of superconducting surfaces to applied RF fields. In this paper we will direct our attention to discussions of recent developments in diagnostic techniqeus, such as thermometry in superfluid helium, and scanning laser acoustic microscopy. 18 refs., 12 figs

  14. Using Pattern Classification and Recognition Techniques for Diagnostic and Prediction

    Directory of Open Access Journals (Sweden)

    MORARIU, N.

    2007-04-01

    Full Text Available The paper presents some aspects regarding the joint use of classification and recognition techniques for the activity evolution diagnostication and prediction by means of a set of indexes. Starting from the indexes set there is defined a measure on the patterns set, measure representing a scalar value that characterizes the activity analyzed at each time moment. A pattern is defined by the values of the indexes set at a given time. Over the classes set obtained by means of the classification and recognition techniques is defined a relation that allows the representation of the evolution from negative evolution towards positive evolution. For the diagnostication and prediction the following tools are used: pattern recognition and multilayer perceptron. The data set used in experiments describes the pollution due to CO2 emission from the consumption of fuels in Europe. The paper also presents the REFORME software written by the authors and the results of the experiment obtained with this software.

  15. A clinicopathological study of various oral cancer diagnostic techniques

    Directory of Open Access Journals (Sweden)

    G Ulaganathan

    2017-01-01

    Full Text Available Oral cancer is one of the most commonly occurring malignant tumors in the head and neck regions with high incident rate and mortality rate in the developed countries than in the developing countries. Generally, the survival rate of cancer patients may increase when diagnosed at early stage, followed by prompt treatment and therapy. Recently, cancer diagnosis and therapy design for a specific cancer patient have been performed with the advanced computer-aided techniques. The responses of the cancer therapy could be continuously monitored to ensure the effectiveness of the treatment process that hardly requires diagnostic result as quick as possible to improve the quality and patient care. This paper gives an overview of oral cancer occurrence, different types, and various diagnostic techniques. In addition, a brief introduction is given to various stages of immunoanalysis including tissue image preparation, whole slide imaging, and microscopic image analysis.

  16. Fusion alpha loss diagnostic for ITER using activation technique

    Czech Academy of Sciences Publication Activity Database

    Bonheure, G.; Hult, M.; González de Orduña, R.; Vermaercke, P.; Murari, A.; Popovichev, S.; Mlynář, Jan

    2011-01-01

    Roč. 86, 6-8 (2011), s. 1298-1301 ISSN 0920-3796. [Symposium on Fusion Technology (SOFT) /26th./. Port o, 27.09.2010-01.10.2010] Institutional research plan: CEZ:AV0Z20430508 Keywords : ITER * fusion product * burning plasma diagnostics * alpha losses * activation technique Subject RIV: BL - Plasma and Gas Discharge Physics Impact factor: 1.490, year: 2011 http://www.sciencedirect.com/science/article/pii/S0920379611002778

  17. Imaging mammary diagnostics. Diagnostic techniques, archetypical findings, differential diagnostcs and interventions. 2. rev. and enl. ed.

    International Nuclear Information System (INIS)

    Heywang-Koebrunner, S.; Schreer, I.

    2008-01-01

    The book includes the following chapters: I. Methodology: anamnesis and interview; clinical evidence, mammography, sonography, magnetic resonance tomography, new imaging techniques (scintigraphy, PET), transcutaneous biopsy, pre-operative marking; II. phenotypes: normal mammary glands, mastopathics, cysts, benign tumors, inflammatory diseases, in-situ carcinomas, invasive carcinomas, lymphomas, other semi-malign and malign tumors, post-traumatic, post-surgical and post-therapeutic changes, skin changes, male mamma, screening, continuative diagnostics of screening evidence and problem solving for symptomatic patients

  18. LeRC rail accelerators: test designs and diagnostic techniques

    International Nuclear Information System (INIS)

    Zana, L.M.; Kerslake, W.R.; Sturman, J.C.; Wang, S.Y.; Terdan, F.F.

    1984-01-01

    The feasibility of using rail accelerators for various in-space and to-space propulsion applications was investigated. A 1 meter, 24 sq mm bore accelerator was designed with the goal of demonstrating projectile velocities of 15 km/sec using a peak current of 200 kA. A second rail accelerator, 1 meter long with a 156.25 sq mm bore, was designed with clear polycarbonate sidewalls to permit visual observation of the plasma arc. A study of available diagnostic techniques and their application to the rail accelerator is presented. Specific topics of discussion include the use of interferometry and spectroscopy to examine the plasma armature as well as the use of optical sensors to measure rail displacement during acceleration. Standard diagnostics such as current and voltage measurements are also discussed. 15 references

  19. Diagnostic accuracy of new imaging techniques in breast diseases

    Energy Technology Data Exchange (ETDEWEB)

    Gordenne, W; Bauduin, E [Liege Univ. (Belgium)

    1989-01-01

    During the last decade, the hypothetical carcinogenic effects of mammography have lead to new technical developments in X-ray diagnosis and to use of other imaging techniques such as ultrasonography (US), transillumination, magnetic resonance imaging (MRI). Many preliminary studies were published but few clinical trials are really convincing. According to the definition of a diagnostic tool, none of these new modalities is supposed to supplant mammography in the diagnosis of breast cancer. Improvements are expected by digital mammography in the near future. (Authors).

  20. Improvement of Railroad Roller Bearing Test Procedures & Development of Roller Bearing Diagnostic Techniques. Volume 2.

    Science.gov (United States)

    1982-04-01

    A comprehensive review of existing basic diagnostic techniques applicable to the railcar roller bearing defect and failure problem was made. Of the potentially feasible diagnostic techniques identified, high frequency vibration was selected for exper...

  1. New diagnostic technique for Zeeman-compensated atomic beam slowing: technique and results

    NARCIS (Netherlands)

    Molenaar, P.A.; Straten, P. van der; Heideman, H.G.M.; Metcalf, H.

    1997-01-01

    We have developed a new diagnostic tool for the study of Zeeman-compensated slowing of an alkali atomic beam. Our time-of-flight technique measures the longitudinal veloc- ity distribution of the slowed atoms with a resolution below the Doppler limit of 30 cm/s. Furthermore, it can map

  2. Resonant laser techniques for combustion and flow diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Fritzon, Rolf

    1998-05-01

    This thesis presents results from two areas of research. Firstly, the resonant coherent laser techniques polarization spectroscopy (PS), degenerate four-wave mixing (DFWM) and stimulated emission (SE) have been developed in the general field of combustion diagnostics. Secondly, laser induced fluorescence (LIF) has been developed and applied for the visualization of mixture fractions in turbulent non reacting flows. PS was developed for instantaneous two-dimensional imaging of minor species in flames, the technique being demonstrated on OH and NO. Various aspects of imaging and of detection in general were investigated. Two-photon induced PS was demonstrated for the detection of NH{sub 3}, CO and N{sub 2} molecules. LIF was monitored simultaneously to allow a quantitative comparison between the techniques. Furthermore, PS and DFWM were developed for instantaneous two-dimensional OH temperature imaging. Through a novel experimental approach based on the use of a dual-wavelength dye laser and a diffraction grating the temperature imaging measurements were performed using only one laser and one CCD camera. A comparison between the two techniques was made. SE was through a crossed-beam arrangement developed for spatially resolved detection of flame species. Two-dimensional LIF was developed and applied for measuring mixture fractions in the shear layer between two co-flowing turbulent gaseous jets. The technique was further applied in a study of the mixing of a turbulent water jet impinging orthogonally onto a flat surface. Average concentration fields in the center-plane of the jet was compared with results from large eddy simulations and with data from the literature 221 refs, 48 figs, 5 tabs

  3. Laser diagnodent: a comparative study with other diagnostic techniques

    International Nuclear Information System (INIS)

    Godinho, Reugma Rego

    2002-01-01

    An evaluation of the Diagnodent equipment (Kavo Company, Germany) for the occlusal caries detection was dane through the comparison with other conventional diagnostic techniques, such as visual inspection, intra-oral micro camera and digital X-ray. The effectiveness of the equipment in the detection of hidden caries and its viability as a diagnosis method for caries in their initial stage was also studied. Fifty eight permanent molars and premolars teeth from patients with age between 6 and 30 years were studied. The obtained results indicated that the conventional methods employed for the caries diagnosis are unable to detect the carious lesion in its initial stage. The Diagnodent equipment has this capability to detect caries presenting a flawless surface, specially the hidden caries, allowing the dentist to decide between a preventive ar a conservative procedure. The main advantage of the Diagnodent is to be an objective method, compared to the visual and radiographic ones, that are dependent on the professional interpretation. The Diagnodent is, therefore, a promising alternative as an objective and standardized diagnosis method for the final diagnostic. (author)

  4. Reliability of diagnostic imaging techniques in suspected acute appendicitis: proposed diagnostic protocol

    International Nuclear Information System (INIS)

    Cura del, J. L.; Oleaga, L.; Grande, D.; Vela, A. C.; Ibanez, A. M.

    2001-01-01

    To study the utility of ultrasound and computed tomography (CT) in case of suspected appendicitis. To determine the diagnostic yield in terms of different clinical contexts and patient characteristics. to assess the costs and benefits of introducing these techniques and propose a protocol for their use. Negative appendectomies, complications and length of hospital stay in a group of 152 patients with suspected appendicitis who underwent ultrasound and CT were compared with those of 180 patients who underwent appendectomy during the same time period, but had not been selected for the first group: these patients costs for each group were calculated. In the first group, the diagnostic value of the clinical signs was also evaluated. The reliability of the clinical signs was limited, while the results with ultrasound and CT were excellent. The incidence of negative appendectomy was 9.6% in the study group and 12.2% in the control group. Moreover, there were fewer complications and a shorter hospital stay in the first group. Among men, however, the rate of negative appendectomy was lower in the control group. The cost of using ultrasound and CT in the management of appendicitis was only slightly higher than that of the control group. Although ultrasound and CT are not necessary in cases in which the probability of appendicitis is low or in men presenting clear clinical evidence, the use of these techniques is indicated in the remaining cases in which appendicitis is suspected. In children, ultrasound is the technique of choice. In all other patients, if negative results are obtained with one of the two techniques, the other should be performed. (Author) 49 refs

  5. Diagnostics

    DEFF Research Database (Denmark)

    Donné, A.J.H.; Costley, A.E.; Barnsley, R.

    2007-01-01

    of the measurements—time and spatial resolutions, etc—will in some cases be more stringent. Many of the measurements will be used in the real time control of the plasma driving a requirement for very high reliability in the systems (diagnostics) that provide the measurements. The implementation of diagnostic systems...... on ITER is a substantial challenge. Because of the harsh environment (high levels of neutron and gamma fluxes, neutron heating, particle bombardment) diagnostic system selection and design has to cope with a range of phenomena not previously encountered in diagnostic design. Extensive design and R......&D is needed to prepare the systems. In some cases the environmental difficulties are so severe that new diagnostic techniques are required. The starting point in the development of diagnostics for ITER is to define the measurement requirements and develop their justification. It is necessary to include all...

  6. New diagnostic technique for Zeeman-compensated atomic beam slowing: technique and results

    OpenAIRE

    Molenaar, P.A.; Straten, P. van der; Heideman, H.G.M.; Metcalf, H.

    1997-01-01

    We have developed a new diagnostic tool for the study of Zeeman-compensated slowing of an alkali atomic beam. Our time-of-flight technique measures the longitudinal veloc- ity distribution of the slowed atoms with a resolution below the Doppler limit of 30 cm/s. Furthermore, it can map the position and velocity distribution of atoms in either ground hyperfine level inside the solenoid without any devices inside the solenoid. The technique reveals the optical pumping ef- fects, and shows in de...

  7. Selection of suitable diagnostic techniques for an RF atmospheric pressure plasma

    International Nuclear Information System (INIS)

    Kong, M.G.; Deng, X.T.

    2001-01-01

    As an early report of our study, this paper summaries the RF atmospheric pressure plasma system we intend to characterize and a number of diagnostic techniques presently under assessment for our plasma rig. By discussing the advantages and disadvantages of these diagnostic techniques at this meeting, we hope to gain feedback and comments to improve our choice of appropriate diagnostic techniques as well as our subsequent application of these techniques to nonthermal RF atmospheric pressure plasmas

  8. Development of advanced strain diagnostic techniques for reactor environments.

    Energy Technology Data Exchange (ETDEWEB)

    Fleming, Darryn D.; Holschuh, Thomas Vernon,; Miller, Timothy J.; Hall, Aaron Christopher; Urrea, David Anthony,; Parma, Edward J.,

    2013-02-01

    The following research is operated as a Laboratory Directed Research and Development (LDRD) initiative at Sandia National Laboratories. The long-term goals of the program include sophisticated diagnostics of advanced fuels testing for nuclear reactors for the Department of Energy (DOE) Gen IV program, with the future capability to provide real-time measurement of strain in fuel rod cladding during operation in situ at any research or power reactor in the United States. By quantifying the stress and strain in fuel rods, it is possible to significantly improve fuel rod design, and consequently, to improve the performance and lifetime of the cladding. During the past year of this program, two sets of experiments were performed: small-scale tests to ensure reliability of the gages, and reactor pulse experiments involving the most viable samples in the Annulated Core Research Reactor (ACRR), located onsite at Sandia. Strain measurement techniques that can provide useful data in the extreme environment of a nuclear reactor core are needed to characterize nuclear fuel rods. This report documents the progression of solutions to this issue that were explored for feasibility in FY12 at Sandia National Laboratories, Albuquerque, NM.

  9. Monte Carlo techniques in diagnostic and therapeutic nuclear medicine

    International Nuclear Information System (INIS)

    Zaidi, H.

    2002-01-01

    Monte Carlo techniques have become one of the most popular tools in different areas of medical radiation physics following the development and subsequent implementation of powerful computing systems for clinical use. In particular, they have been extensively applied to simulate processes involving random behaviour and to quantify physical parameters that are difficult or even impossible to calculate analytically or to determine by experimental measurements. The use of the Monte Carlo method to simulate radiation transport turned out to be the most accurate means of predicting absorbed dose distributions and other quantities of interest in the radiation treatment of cancer patients using either external or radionuclide radiotherapy. The same trend has occurred for the estimation of the absorbed dose in diagnostic procedures using radionuclides. There is broad consensus in accepting that the earliest Monte Carlo calculations in medical radiation physics were made in the area of nuclear medicine, where the technique was used for dosimetry modelling and computations. Formalism and data based on Monte Carlo calculations, developed by the Medical Internal Radiation Dose (MIRD) committee of the Society of Nuclear Medicine, were published in a series of supplements to the Journal of Nuclear Medicine, the first one being released in 1968. Some of these pamphlets made extensive use of Monte Carlo calculations to derive specific absorbed fractions for electron and photon sources uniformly distributed in organs of mathematical phantoms. Interest in Monte Carlo-based dose calculations with β-emitters has been revived with the application of radiolabelled monoclonal antibodies to radioimmunotherapy. As a consequence of this generalized use, many questions are being raised primarily about the need and potential of Monte Carlo techniques, but also about how accurate it really is, what would it take to apply it clinically and make it available widely to the medical physics

  10. Diagnostic imaging techniques in Rubinstein-Taybi syndrome

    International Nuclear Information System (INIS)

    Albanese, A.; Carcione, A.; Benenati, A.; Albano, S.; Rubino, F.P.; Reina, C.; Verde, V.; Giuffre, L.; Corsello, G.; Cammarata, M.; Piccione, M.

    1991-01-01

    Both etiology and pathogenesis of Rubinstein-Taybi syndrome (RTS) are still questionable, even though a genetic factor seems to be certain. A typical face, psychomotor delay, and thumb and halluces abnormalities (big, prevalently short, and often 'spoon-like' toes) are the main characteristic patterns of RTS. Eight subjects (4 male and 3 female children aged 26 days-7 years, and a 31-year old woman, mother of 1 of the affected children) with different signs of RTS were studied over the last 3 years. The results are here reported, with a special emphasis on malformations detected with conventional radiography (Rx), Computerized Tomography (CT), and ultrasound (US). Evaluated parameters were thumbs and halluces (Rx), bone age and skeleton (Rx), cranium (Rx) and encephalon (US, CT), cryptochidism (US, CT), and urogical (Rx, US) and carciovascolar (US) system. Atypical face and psycomotor delay were found in all cases, while thumb and halluces abnormalities were observed only in 6 cases. Among several clinical signs of RTS, we found: severe (<3rd centile) bone maturation delay in 4 cases; skull volume reduction (<50th centile) in 3 subjects and microcrania in 4; skeletal abnormalities in 7 cases (5 of them positive for bilateral coxofemoral abnormalities); urinary tract (4 cases) and cardiovascular (3 cases) malformation; and cryptorcidism in 3 of 4 males. A case was diagnosed during neonatal period (within the first month of life) it was a rare case associated with a variant form of Dandy-Walker anomaly; semiologic similarities were observed between mother and daughter patients. X-rays, US and CT rarely play an important role in the diagnosis of RTS, considering the several clinical signs, mainly tha face, affecting the patients. However, diagnostic imaging techniques help diagnose hidden malformations and confirm and integrate clinical signs

  11. Indications and new diagnostic techniques in micturating cystourethrographic studies

    International Nuclear Information System (INIS)

    Schuster, W.; Bruenger, J.

    1978-01-01

    Urological radiographic procedures on children are of great importance. The frequency of examinations is comparable to the number of Gl tract studies. In diagnosing chronically recurrent urinary tract infections, micturating cystourethrography is a valuable addition to excretory urography. Indications and performance of micturating cystourethrography at juvenile age are described. All measures reducing radiation exposure must be taken into consideration. New technological devices grant improved diagnostic information with a minimal radiation exposure for patients. (orig.) [de

  12. Tunable diode laser spectroscopy as a technique for combustion diagnostics

    International Nuclear Information System (INIS)

    Bolshov, M.A.; Kuritsyn, Yu.A.; Romanovskii, Yu.V.

    2015-01-01

    Tunable diode laser absorption spectroscopy (TDLAS) has become a proven method of rapid gas diagnostics. In the present review an overview of the state of the art of TDL-based sensors and their applications for measurements of temperature, pressure, and species concentrations of gas components in harsh environments is given. In particular, the contemporary tunable diode laser systems, various methods of absorption detection (direct absorption measurements, wavelength modulation based phase sensitive detection), and relevant algorithms for data processing that improve accuracy and accelerate the diagnostics cycle are discussed in detail. The paper demonstrates how the recent developments of these methods and algorithms made it possible to extend the functionality of TDLAS in the tomographic imaging of combustion processes. Some prominent examples of applications of TDL-based sensors in a wide range of practical combustion aggregates, including scramjet engines and facilities, internal combustion engines, pulse detonation combustors, and coal gasifiers, are given in the final part of the review. - Highlights: • Overview of modern TDL-based sensors for combustion • TDL systems, methods of absorption detection and algorithms of data processing • Prominent examples of TDLAS diagnostics of the combustion facilities • Extension of the TDLAS on the tomographic imaging of combustion processes

  13. A review on diagnostic techniques for brucellosis | Kaltungo | African ...

    African Journals Online (AJOL)

    ... but has not been validated for standard laboratory use. This paper highlights useful samples and, especially the different conventional to more sophisticated molecular techniques for the diagnosis of brucellosis. Keywords: Brucellosis, diagnosis, techniques. African Journal of Biotechnology, Vol. 13(1), pp. 1-10, 1 January, ...

  14. Endoscopy as a diagnostic and therapeutic alternative technique of taeniasis.

    Science.gov (United States)

    Canaval Zuleta, Héctor Julián; Company Campins, María M; Dolz Abadía, Carlos

    2016-06-01

    Despite a low incidence in developed countries, gastrointestinal taeniasis should be suspected in patients with abdominal pain, diarrhea, anemia, and/or malabsorption of unknown origin, even more so if they come from endemic regions or areas with poor hygienic and alimentary habits. Diagnosis is traditionally reached by identifying the parasite in stools, but more recently both serological and immunological approaches are also available. Based on a patient diagnosed by gastroscopy, a literature review was undertaken of patients diagnosed by endoscopy. We discuss endoscopy as diagnostic modality, and the effectiveness and safety that endoscopic treatment may provide in view of the potential risk for neurocysticercosis.

  15. Endoscopy as a diagnostic and therapeutic alternative technique of taeniasis

    Directory of Open Access Journals (Sweden)

    Héctor Julian Canaval-Zuleta

    Full Text Available Despite a low incidence in developed countries, gastrointestinal taeniasis should be suspected in patients with abdominal pain, diarrhea, anemia, and/or malabsorption of unknown origin, even more so if they come from endemic regions or areas with poor hygienic and alimentary habits. Diagnosis is traditionally reached by identifying the parasite in stools, but more recently both serological and immunological approaches are also available. Based on a patient diagnosed by gastroscopy, a literature review was undertaken of patients diagnosed by endoscopy. We discuss endoscopy as diagnostic modality, and the effectiveness and safety that endoscopic treatment may provide in view of the potential risk for neurocysticercosis.

  16. Action Research to Improve the Learning Space for Diagnostic Techniques

    Directory of Open Access Journals (Sweden)

    Ellen Ariel

    2015-08-01

    Full Text Available The module described and evaluated here was created in response to perceived learning difficulties in diagnostic test design and interpretation for students in third-year Clinical Microbiology. Previously, the activities in lectures and laboratory classes in the module fell into the lower cognitive operations of “knowledge” and “understanding.” The new approach was to exchange part of the traditional activities with elements of interactive learning, where students had the opportunity to engage in deep learning using a variety of learning styles. The effectiveness of the new curriculum was assessed by means of on-course student assessment throughout the module, a final exam, an anonymous questionnaire on student evaluation of the different activities and a focus group of volunteers. Although the new curriculum enabled a major part of the student cohort to achieve higher pass grades (p < 0.001, it did not meet the requirements of the weaker students, and the proportion of the students failing the module remained at 34%. The action research applied here provided a number of valuable suggestions from students on how to improve future curricula from their perspective. Most importantly, an interactive online program that facilitated flexibility in the learning space for the different reagents and their interaction in diagnostic tests was proposed. The methods applied to improve and assess a curriculum refresh by involving students as partners in the process, as well as the outcomes, are discussed.

  17. Action Research to Improve the Learning Space for Diagnostic Techniques.

    Science.gov (United States)

    Ariel, Ellen; Owens, Leigh

    2015-12-01

    The module described and evaluated here was created in response to perceived learning difficulties in diagnostic test design and interpretation for students in third-year Clinical Microbiology. Previously, the activities in lectures and laboratory classes in the module fell into the lower cognitive operations of "knowledge" and "understanding." The new approach was to exchange part of the traditional activities with elements of interactive learning, where students had the opportunity to engage in deep learning using a variety of learning styles. The effectiveness of the new curriculum was assessed by means of on-course student assessment throughout the module, a final exam, an anonymous questionnaire on student evaluation of the different activities and a focus group of volunteers. Although the new curriculum enabled a major part of the student cohort to achieve higher pass grades (p < 0.001), it did not meet the requirements of the weaker students, and the proportion of the students failing the module remained at 34%. The action research applied here provided a number of valuable suggestions from students on how to improve future curricula from their perspective. Most importantly, an interactive online program that facilitated flexibility in the learning space for the different reagents and their interaction in diagnostic tests was proposed. The methods applied to improve and assess a curriculum refresh by involving students as partners in the process, as well as the outcomes, are discussed. Journal of Microbiology & Biology Education.

  18. Dose classification scheme for digital imaging techniques in diagnostic radiology

    International Nuclear Information System (INIS)

    Hojreh, A.

    2002-04-01

    Purpose: image quality in diagnostic radiology is determined in crucial extent by the signal-noise-ratio, which is proportional to the applied x-ray dose. Onward technological developments in the diagnostic radiology are therefore frequently connected with a dose increase, which subjectively is hardly or even not perceptible. The aim of this work was to define reproducible standards for image quality as a function of dose and expected therapeutical consequence in case of computed tomography of the paranasal sinuses and the upper and lower jaw (dental CT), whereby practical-clinical purposes are considered. Materials and methods: the image quality of computed tomography of the paranasal sinuses and dental CT was determined by standard deviation of the CT-numbers (pixel noise) in a region of interest of the phantom of American Association of Physicists in Medicine (AAPM phantom) and additionally in the patients CT images. The diagnostic quality of the examination was classified on the basis of patients CT images in three dose levels (low dose, standard dose and high dose). Results: the pixel noise of CT of the paranasal sinuses with soft tissue reconstruction amounts to 19.3 Hounsfield units (HU) for low dose, 8.8 HU for standard dose, and below 8 HU for high dose. The pixel noise of the dental CT with bone (high resolution) reconstruction amounts to 344 HU for low dose, 221 HU for standard dose, and below 200 HU for high dose. Suitable indications for low dose CT are the scanning of body regions with high contrast differences, like the bony delimitations of air-filled spaces of the facial bones, and radiological follow-up examinations with dedicated questions such as axis determination in dental implantology, as well as the images of objects with small diameter such as in case of children. The standard dose CT can be recommended for all cases, in which precise staging of the illness plays an indispensable role for the diagnosis and therapy planning. With high dose

  19. Novel non-intercepting diagnostic techniques for low-emittance relativistic electron beams

    International Nuclear Information System (INIS)

    Moran, M.J.; Chang, B.

    1988-01-01

    Relativistic electron beams are being generated with emittances low enough that diffraction radiation can be used for beam diagnostics. Techniques based on diffraction radiation can be used to measure the beam transverse momentum distribution and to measure the transverse spatial distribution. The radiation is intense and can be in the visible spectral region where optical diagnostic techniques can be used to maximum advantage. 4 refs. 3 figs

  20. Two cases of colossal heamtometra in old women with a difficult preoperative diagnostic technique

    International Nuclear Information System (INIS)

    Aono, Kaname; Fukumoto, Satoru

    1980-01-01

    With the progress in diagnostic imaging techniques, the preoperative diagnostic technique for lesion in the pelvic cavity has become comparatively easy and its clinical usefulness is in high estimation. However, in case of an atypical lesion, it is not always easy to recognize the original organ by traditional imaging pattern. In the present report two cases of colossal hematometra in old women which presented a cystic lesion pattern are dealt with and discussed from a point of medical imagings for diagnosis. (author)

  1. Diagnostic methods and techniques in cervical cancer prevention Part II: Molecular diagnostics of HPV infection

    Directory of Open Access Journals (Sweden)

    Adriana Vince,

    2010-02-01

    Full Text Available Clinical diagnostics of HPV infection is based on analytically andclinically validated assays for qualitative detection of HPV DNAfrom high risk genotypes. New generation of HPV DNA assayscombines qualitative detection of 12 high-risk HPV genotypeswith HPV-16 and HPV-18 genotyping. New generation of HPVmolecular assays designed to increase clinical specificity of moleculartesting is based on detection of mRNA for E6 and E7.

  2. Computer Tomography: A Novel Diagnostic Technique used in Horses

    African Journals Online (AJOL)

    In Veterinary Medicine, Computer Tomography (CT scan) is used more often in dogs and cats than in large animals due to their small size and ease of manipulation. This paper, however, illustrates the use of the technique in horses. CT scan was used in the diagnosis of two conditions of the head and limbs, namely alveolar ...

  3. Unbiased stereologic techniques for practical use in diagnostic histopathology

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt

    1995-01-01

    Grading of malignancy by the examination of morphologic and cytologic details in histologic sections from malignant neoplasms is based exclusively on qualitative features, associated with significant subjectivity, and thus rather poor reproducibility. The traditional way of malignancy grading may...... by introducing quantitative techniques in the histopathologic discipline of malignancy grading. Unbiased stereologic methods, especially based on measurements of nuclear three-dimensional mean size, have during the last decade proved their value in this regard. In this survey, the methods are reviewed regarding...... the basic technique involved, sampling, efficiency, and reproducibility. Various types of cancers, where stereologic grading of malignancy has been used, are reviewed and discussed with regard to the development of a new objective and reproducible basis for carrying out prognosis-related malignancy grading...

  4. Diagnostic analysis of vibration signals using adaptive digital filtering techniques

    Science.gov (United States)

    Jewell, R. E.; Jones, J. H.; Paul, J. E.

    1983-01-01

    Signal enhancement techniques are described using recently developed digital adaptive filtering equipment. Adaptive filtering concepts are not new; however, as a result of recent advances in microprocessor-based electronics, hardware has been developed that has stable characteristics and of a size exceeding 1000th order. Selected data processing examples are presented illustrating spectral line enhancement, adaptive noise cancellation, and transfer function estimation in the presence of corrupting noise.

  5. Development of fault diagnostic technique using reactor noise analysis

    International Nuclear Information System (INIS)

    Park, Jin Ho; Kim, J. S.; Oh, I. S.; Ryu, J. S.; Joo, Y. S.; Choi, S.; Yoon, D. B.

    1999-04-01

    The ultimate goal of this project is to establish the analysis technique to diagnose the integrity of reactor internals using reactor noise. The reactor noise analyses techniques for the PWR and CANDU NPP(Nuclear Power Plants) were established by which the dynamic characteristics of reactor internals and SPND instrumentations could be identified, and the noise database corresponding to each plant(both Korean and foreign one) was constructed and compared. Also the change of dynamic characteristics of the Ulchin 1 and 2 reactor internals were simulated under presumed fault conditions. Additionally portable reactor noise analysis system was developed so that real time noise analysis could directly be able to be performed at plant site. The reactor noise analyses techniques developed and the database obtained from the fault simulation, can be used to establish a knowledge based expert system to diagnose the NPP's abnormal conditions. And the portable reactor noise analysis system may be utilized as a substitute for plant IVMS(Internal Vibration Monitoring System). (author)

  6. Development of fault diagnostic technique using reactor noise analysis

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jin Ho; Kim, J. S.; Oh, I. S.; Ryu, J. S.; Joo, Y. S.; Choi, S.; Yoon, D. B

    1999-04-01

    The ultimate goal of this project is to establish the analysis technique to diagnose the integrity of reactor internals using reactor noise. The reactor noise analyses techniques for the PWR and CANDU NPP(Nuclear Power Plants) were established by which the dynamic characteristics of reactor internals and SPND instrumentations could be identified, and the noise database corresponding to each plant(both Korean and foreign one) was constructed and compared. Also the change of dynamic characteristics of the Ulchin 1 and 2 reactor internals were simulated under presumed fault conditions. Additionally portable reactor noise analysis system was developed so that real time noise analysis could directly be able to be performed at plant site. The reactor noise analyses techniques developed and the database obtained from the fault simulation, can be used to establish a knowledge based expert system to diagnose the NPP's abnormal conditions. And the portable reactor noise analysis system may be utilized as a substitute for plant IVMS(Internal Vibration Monitoring System). (author)

  7. Diagnostics of gas behind shock waves by refractive optical techniques

    International Nuclear Information System (INIS)

    Blaha, J.

    In a brief outline of optical methods for measuring neutral gas and plasma parameters, techniques are specifically dealt with based on the interferometric measurement of the refractive index. The investigation is shown of gas density changes in a shock tube using the optical Mach-Zehnder interferometer. While in a neutral gas the refractive index is determined by gas density, in a plasma the effects of all components, ie., electrons, ions and atoms are additive. The contributions to refraction from the various components may, in view of the different character and frequencies of the components, be resolved by measurement on more than one wavelength. (J.U.)

  8. Analysis of diagnostic calorimeter data by the transfer function technique

    Energy Technology Data Exchange (ETDEWEB)

    Delogu, R. S., E-mail: rita.delogu@igi.cnr.it; Pimazzoni, A.; Serianni, G. [Consorzio RFX, Corso Stati Uniti, 35127 Padova (Italy); Poggi, C.; Rossi, G. [Università degli Studi di Padova, Via 8 Febbraio 1848, 35122 Padova (Italy)

    2016-02-15

    This paper describes the analysis procedure applied to the thermal measurements on the rear side of a carbon fibre composite calorimeter with the purpose of reconstructing the energy flux due to an ion beam colliding on the front side. The method is based on the transfer function technique and allows a fast analysis by means of the fast Fourier transform algorithm. Its efficacy has been tested both on simulated and measured temperature profiles: in all cases, the energy flux features are well reproduced and beamlets are well resolved. Limits and restrictions of the method are also discussed, providing strategies to handle issues related to signal noise and digital processing.

  9. The influence on finite measurement accuracy on the SWE-to-PWE antenna diagnostics technique

    DEFF Research Database (Denmark)

    Cappellin, Cecilia; Breinbjerg, Olav; Frandsen, Aksel

    2006-01-01

    A new antenna diagnostics technique based on the transformation of the spherical wave expansion (SWE) into the plane wave expansion (PWE) is proposed. The new technique allows the recovery of the plane wave spectrum in the visible region, and in principle also in part of the invisible region, from...

  10. Diagnostics of detector tube impacting with wavelet techniques

    Energy Technology Data Exchange (ETDEWEB)

    Racz, A. [KFKI-AEKI Applied Reactor Physics, Budapest (Hungary); Pazsit, I. [Chalmers Univ. of Tech., Goeteborg (Sweden). Dept. of Reactor Physics

    1997-12-08

    A neutron noise based method is proposed for the detection of impacting of detector tubes in BWRs. The basic idea relies on the assumption that non-stationary transients (e.g. fuel box vibrations) may be induced at impacting. Such short-lived transients are difficult to detect by spectral analysis methods. However, their presence in the detector signal can be detected by wavelet analysis. A simple wavelet technique, the so-called Haar transform, is suggested for the detection of impacting. Tests of the proposed method have been performed with success on both simulated data with controlled impacting as well as with real measurement data. The simulation model as well as the results of the wavelet analysis are reported in this paper. The source code written in MATLAB are available at a public ftp site. The necessary information to reproduce the simulation results is also reported. (author).

  11. Diagnostics of detector tube impacting with wavelet techniques

    Energy Technology Data Exchange (ETDEWEB)

    Racz, A.; Pazsit, I

    1998-04-01

    A neutron noise based method is proposed for the detection of impacting of detector tubes in BWRs. The basic idea relies on the assumption that non-stationary transients (e.g. fuel box vibrations) may be induced at impacting. Such short-lived transients are difficult to detect by spectral analysis methods. However, their presence in the detector signal can be detected by wavelet analysis. A simple wavelet technique, the so-called Haar transform, is suggested for the detection of impacting. Tests of the proposed method have been performed with success on both simulated data with controlled impacting as well as with real measurement data. The simulation model as well as the results of the wavelet analysis are reported in this paper. The source codes written in MATLAB[reg] are available at a public ftp site. The necessary information to reproduce the simulation results is also reported.

  12. Mild cognitive impairment. Diagnostic value of different MR techniques

    International Nuclear Information System (INIS)

    Hauser, T.; Stieltjes, B.; Essig, M.; Thomann, P.A.

    2011-01-01

    In view of an increasingly aging population the prevalence of dementia is also expected to increase rapidly. As well as clinical, neuropsychological and laboratory procedures magnetic resonance imaging (MRI) plays an important role in the early diagnosis of dementia which is important in the precursor stage of mild cognitive impairment (MCI). On the one hand this stage is associated with an increased risk of dementia and on the other hand an early treatment in this stage could attenuate development of the disease. In addition to morphological changes different functional MRI techniques can help in the early diagnosis of dementia and the precursor stages. Moreover, it is important to detect those MCI patients who are at particularly risk for developing dementia. In the differentiation of converters to non-converters initial studies suggest that particularly voxel-based morphometry, MR spectroscopy and diffusion tensor imaging can provide important additional information. (orig.) [de

  13. Unbiased stereologic techniques for practical use in diagnostic histopathology

    DEFF Research Database (Denmark)

    Sørensen, Flemming Brandt

    1995-01-01

    by introducing quantitative techniques in the histopathologic discipline of malignancy grading. Unbiased stereologic methods, especially based on measurements of nuclear three-dimensional mean size, have during the last decade proved their value in this regard. In this survey, the methods are reviewed regarding......Grading of malignancy by the examination of morphologic and cytologic details in histologic sections from malignant neoplasms is based exclusively on qualitative features, associated with significant subjectivity, and thus rather poor reproducibility. The traditional way of malignancy grading may...... of solid tumors. This new, unbiased attitude to malignancy grading is associated with excellent virtues, which ultimately may help the clinician in the choice of optimal treatment of the individual patient suffering from cancer. Stereologic methods are not solely applicable to the field of malignancy...

  14. Valve Calcification in Aortic Stenosis: Etiology and Diagnostic Imaging Techniques

    Directory of Open Access Journals (Sweden)

    María Manuela Izquierdo-Gómez

    2017-01-01

    Full Text Available Aortic stenosis is the most common valvulopathy in the Western world. Its prevalence has increased significantly in recent years due to population aging; hence, up to 8% of westerners above the age of 84 now have severe aortic stenosis (Lindroos et al., 1993. This causes increased morbidity and mortality and therein lies the importance of adequate diagnosis and stratification of the degree of severity which allows planning the best therapeutic option in each case. Long understood as a passive age-related degenerative process, it is now considered a rather more complex entity involving mechanisms and factors similar to those of atherosclerosis (Stewart et al., 1997. In this review, we summarize the pathophysiological mechanisms underlying the onset and progression of the disease and analyze the current role of cardiac imaging techniques for diagnosis.

  15. [THE CYTOMETRIC TECHNIQUE OF BINDING OF EOSIN-5-MALEIMIDE IN DIAGNOSTIC OF INHERENT SPHEROCYTOSIS].

    Science.gov (United States)

    Kuzminova, J A; Plyasunova, S A; Jogov, V V; Smetanina, N S

    2016-03-01

    The laboratory diagnostic of inherent spherocytosis is based on detection of spherocytes in peripheral blood, decreasing of index of sphericity, decreasing of osmotic resistance of erythrocytes. The new test of diagnostic of hereditary spherocytosis build on molecular defect was developed on the basis of binding extracellular fragments of protein of band 3 with eosin-5-maleimide (EMA-test). The study was carried out to implement comparative analysis of sensitivity and specificity of techniques applied to diagnose inherent spherocytosis. The sampling of 94 patients with various forms of anemias was analyzed All patients were applied complex clinical laboratory examination including analysis of osmotic resistance of erythrocytes, erythrocytometry and EMA-test as specific techniques of diagnostic of inherent spherocytosis. In 51 out of 94 patients (54%) decreasing of values of EMA-test was detected and in 47 patients diagnosis of inherent spherocytosis was confirmed. The standard values of EMA-test were established in 43 patients (46%) and 12 patients out of them with established diagnosis of inherent spherocytosis. Therefore, sensitivity of EMA-test made up to 79% and specificity - 80%. The most sensitive techniques of diagnostic remain osmotic resistance of erythrocytes (91%) and index of sphericity (up to 96%). But the highest specificity in this respect has EMA-test (80%). Nowadays, none of implemented techniques of diagnostic of inherent spherocytosis can be applied as a universal one. The implementation of complex examination is needed for proper diagnostic of disease.

  16. The pulses as a diagnostic technique in the sun

    International Nuclear Information System (INIS)

    Das, G.C.

    1980-01-01

    In this paper we discuss a method of finding physical parameters by studying the pulses in the Sun. For the sake of a mathematical approach, we consider an ideal, highly relevant model which could exist in the Sun with the effects of ionization, due to which there will be a continuous formation of ionized particles. It is observed that the pulse originated at the centre of a dipole field propagates along the magnetic field. We derive a dispersion relation for these types of pulses, propagating from the centre to the solar surface. The time taken by the pulse from its source to the solar surface is also estimated, with due account of the ionization effects on the pulse. Without proper account of these effects, the technique employed in determing the physical parameters may lead to error. Temporal and spatial damping of the pulses lead to estimates of the velocity distribution of the ionized particles and of the amplitude of the magnetic field of the wave in pulse. (orig.)

  17. Proton current measurements using the prompt gamma ray diagnostic technique

    International Nuclear Information System (INIS)

    Leeper, R.J.; Burns, E.J.T.; Johnson, D.J.; McMurtry, W.M.

    1981-01-01

    Prompt gamma ray signals from the nuclear reaction 7 Li(p,γ) 8 Be have been used to make time resolved proton current measurements. In these measurements, the proton beam was allowed to strike cylindrical thick lithium metal targets. The time integrated proton current was measured using gamma activation of copper via the reaction 63 Cu(γ,n) 62 Cu(β+). The positron activity of the copper sample was easily measured using coincidence counting techniques. The number of 62 Cu atoms produced per proton incident on a thick Li metal target was determined with separate calibration runs performed on the Sandia 2.5 MeV Van de Graaff accelerator. The time history of the prompt gamma production was measured using six EGG NPM-54 scintillator photomultiplier combinations shielded by 96.5 cm of concrete and 5.1 cm of Pb. The use of six scintillator photomultiplier combinations was necessary to increase the statistical precision of the data. The normalization of the prompt gamma time history data with the total time integrated proton-current measurement yielded the absolute time resolved proton current on target. Data from runs performed on the Sandia Proto I accelerator will be presented

  18. Review of Physicochemical-Based Diagnostic Techniques for Assessing Insulation Condition in Aged Transformers

    Directory of Open Access Journals (Sweden)

    Janvier Sylvestre N’cho

    2016-05-01

    Full Text Available A power transformer outage has a dramatic financial consequence not only for electric power systems utilities but also for interconnected customers. The service reliability of this important asset largely depends upon the condition of the oil-paper insulation. Therefore, by keeping the qualities of oil-paper insulation system in pristine condition, the maintenance planners can reduce the decline rate of internal faults. Accurate diagnostic methods for analyzing the condition of transformers are therefore essential. Currently, there are various electrical and physicochemical diagnostic techniques available for insulation condition monitoring of power transformers. This paper is aimed at the description, analysis and interpretation of modern physicochemical diagnostics techniques for assessing insulation condition in aged transformers. Since fields and laboratory experiences have shown that transformer oil contains about 70% of diagnostic information, the physicochemical analyses of oil samples can therefore be extremely useful in monitoring the condition of power transformers.

  19. A Hybrid Neural Network-Genetic Algorithm Technique for Aircraft Engine Performance Diagnostics

    Science.gov (United States)

    Kobayashi, Takahisa; Simon, Donald L.

    2001-01-01

    In this paper, a model-based diagnostic method, which utilizes Neural Networks and Genetic Algorithms, is investigated. Neural networks are applied to estimate the engine internal health, and Genetic Algorithms are applied for sensor bias detection and estimation. This hybrid approach takes advantage of the nonlinear estimation capability provided by neural networks while improving the robustness to measurement uncertainty through the application of Genetic Algorithms. The hybrid diagnostic technique also has the ability to rank multiple potential solutions for a given set of anomalous sensor measurements in order to reduce false alarms and missed detections. The performance of the hybrid diagnostic technique is evaluated through some case studies derived from a turbofan engine simulation. The results show this approach is promising for reliable diagnostics of aircraft engines.

  20. Development of technique for diagnostics of social reserves of development of collective labour potential

    OpenAIRE

    Голубєв, Станіслав Миколайович

    2015-01-01

    The problems of diagnostics of social reserves of the collective labour potential are considered in the article. The aim of this study is to develop diagnostic techniques of social reserves of the collective labour potential in the work and the essence of the concept of "social reserves" as a subject of study of economics and their features in the study of collective labour potential. The use of these reserves can increase the efficiency of the labour collective processes by improving coopera...

  1. Case-based reasoning diagnostic technique based on multi-attribute similarity

    Energy Technology Data Exchange (ETDEWEB)

    Makoto, Takahashi [Tohoku University, Miyagi (Japan); Akio, Gofuku [Okayama University, Okayamaa (Japan)

    2014-08-15

    Case-based diagnostic technique has been developed based on the multi-attribute similarity. Specific feature of the developed system is to use multiple attributes of process signals for similarity evaluation to retrieve a similar case stored in a case base. The present technique has been applied to the measurement data from Monju with some simulated anomalies. The results of numerical experiments showed that the present technique can be utilizes as one of the methods for a hybrid-type diagnosis system.

  2. Evaluation of techniques for inspection and diagnostics of HWR pressure tubes

    International Nuclear Information System (INIS)

    Choi, Jong-Ho

    2008-01-01

    Efficient and accurate inspection and diagnostic techniques for various reactor components and systems, especially pressure tubes for Heavy Water Reactors (HWRs), are an important factor in assuring reliable and safe plant operation. To foster international collaboration in the efficient and safe use of nuclear power, the IAEA conducted a Coordinated Research Project (CRP) on Inter-comparison of Techniques for HWR Pressure Tube Inspection and Diagnostics. The objective of the CRP was to inter-compare inspection and diagnostic techniques, in use and being developed, for structural integrity assessment of HWR pressure tubes. During the first phase of the CRP, participants investigated the capability of different techniques to detect and characterize flaws. During the second phase, participants collaborated to determine the hydrogen concentration and to detect and characterize hydride blisters in zirconium alloy pressure tubes. Eight organizations from six countries, which operate HWRs, have participated in this CRP, Most of the techniques examined are well established and many of them are regularly used during in-service inspection of pressure tubes. The inter-comparison of these techniques provides a platform for identifying a particular technique (or a set of techniques), which is more accurate and reliable as compared to others for a specified task. The CRP also witnessed some new methodologies, which can be implemented on in-service inspection tools. These new techniques could complement the existing ones to overcome their limitations, thereby improving the reliability and accuracy of in-service inspection. This CRP also identified future areas of research and development. (author)

  3. Textbook of focusing techniques in diagnostic radiography. 5. new rev. ed.

    International Nuclear Information System (INIS)

    Bosnjakovic-Buescher, S.; Riegler-Bubeck, C.; Zimmer-Brossy, M.; Bast, B.

    1998-01-01

    This 5th edition of the standard work on focusing techniques in diagnostic radiography is a guide for X-ray medical technicians and radiologists wishing to optimize their skills and produce images of high technical standard and diagnostic value. The major part of the textbook deals with the focusing and imaging techniques for evaluation of the skeleton and inner body organs. The new edition includes the current legal provisions for radiological protection and the latest quality assurance legislation. It is an indispensable source of reference for clinical departments, radiographic practice, and training institutions. (orig./CB) [de

  4. The radiation protection optimisation in contrast X-ray diagnostic techniques

    International Nuclear Information System (INIS)

    Markovic, S.; Pavlovic, R.

    1995-01-01

    In the class of artificial sources, X-ray diagnostic techniques irradiate global population with more than 90 % share in total dose. At the same time this is the only area with high possibilities in collective dose reduction without important investments. Exposure of the medical team is mainly related to unnecessary irradiation. Eliminating this unnecessary irradiation quality of diagnostic information remains undisturbed. From the radiation protection point of view the most critical X-ray diagnostic method is angiography. This paper presents the radiation protection optimisation calculation of the protective lead thickness using the Cost - Benefit analysis technique. The obtained numerical results are based on calculated collective dose, the estimated prices of the lead and lead glass thickness and the adopted price for monetary value of the collective dose unit α. (author) 3 figs., 10 refs

  5. The radiation protection optimisation in contrast X-ray diagnostic techniques

    Energy Technology Data Exchange (ETDEWEB)

    Markovic, S; Pavlovic, R [Inst. of Nuclear Science Vinca, Belgrade (Yugoslavia). Radiation and Environmental Protection Lab.; Boreli, F [Fac. of Electrical Engineering, Belgrade (Yugoslavia)

    1996-12-31

    In the class of artificial sources, X-ray diagnostic techniques irradiate global population with more than 90 % share in total dose. At the same time this is the only area with high possibilities in collective dose reduction without important investments. Exposure of the medical team is mainly related to unnecessary irradiation. Eliminating this unnecessary irradiation quality of diagnostic information remains undisturbed. From the radiation protection point of view the most critical X-ray diagnostic method is angiography. This paper presents the radiation protection optimisation calculation of the protective lead thickness using the Cost - Benefit analysis technique. The obtained numerical results are based on calculated collective dose, the estimated prices of the lead and lead glass thickness and the adopted price for monetary value of the collective dose unit {alpha}. (author) 3 figs., 10 refs.

  6. The application of DECnet TTT technique in beam diagnostical system of SSC central region

    International Nuclear Information System (INIS)

    Zhang Guixu; Huang Tuanhua

    1997-01-01

    The DECnet TTT technique and the real time network communication based on DECnet TTT are presented. Information can be transferred between console and diagnostical system via DECnet communication, so all kinds of operation can be done on console. The working computer of HIRFL console is VAX8350

  7. New perineal injection technique for pudendal nerve infiltration in diagnostic and therapeutic procedures

    NARCIS (Netherlands)

    Weinschenk, Stefan; Hollmann, Markus W.; Strowitzki, Thomas

    2016-01-01

    Pudendal nerve injection is used as a diagnostic procedure in the vulvar region and for therapeutic purposes, such as in vulvodynia. Here, we provide a new, easy-to-perform perineal injection technique. We analyzed 105 perineal injections into the pudendal nerve with a local anesthetic (LA),

  8. Intercomparison of techniques for inspection and diagnostics of heavy water reactor pressure tubes. Additional information

    International Nuclear Information System (INIS)

    2009-03-01

    The reports from Argentina, Canada, India, Korea and Romania are presented concerning the projects carried out under the Coordinated Research Program (CRP) I3.30.10 of the International Agency for Atomic Energy - Vienna related to 'Intercomparison of Techniques for Pressure Tube Inspection and Diagnostics'

  9. On-line diagnostic techniques for air-operated control valves based on time series analysis

    International Nuclear Information System (INIS)

    Ito, Kenji; Matsuoka, Yoshinori; Minamikawa, Shigeru; Komatsu, Yasuki; Satoh, Takeshi.

    1996-01-01

    The objective of this research is to study the feasibility of applying on-line diagnostic techniques based on time series analysis to air-operated control valves - numerous valves of the type which are used in PWR plants. Generally the techniques can detect anomalies by failures in the initial stages for which detection is difficult by conventional surveillance of process parameters measured directly. However, the effectiveness of these techniques depends on the system being diagnosed. The difficulties in applying diagnostic techniques to air-operated control valves seem to come from the reduced sensitivity of their response as compared with hydraulic control systems, as well as the need to identify anomalies in low level signals that fluctuate only slightly but continuously. In this research, simulation tests were performed by setting various kinds of failure modes for a test valve with the same specifications as of a valve actually used in the plants. Actual control signals recorded from an operating plant were then used as input signals for simulation. The results of the tests confirmed the feasibility of applying on-line diagnostic techniques based on time series analysis to air-operated control valves. (author)

  10. Advanced Laser-Based Techniques for Gas-Phase Diagnostics in Combustion and Aerospace Engineering.

    Science.gov (United States)

    Ehn, Andreas; Zhu, Jiajian; Li, Xuesong; Kiefer, Johannes

    2017-03-01

    Gaining information of species, temperature, and velocity distributions in turbulent combustion and high-speed reactive flows is challenging, particularly for conducting measurements without influencing the experimental object itself. The use of optical and spectroscopic techniques, and in particular laser-based diagnostics, has shown outstanding abilities for performing non-intrusive in situ diagnostics. The development of instrumentation, such as robust lasers with high pulse energy, ultra-short pulse duration, and high repetition rate along with digitized cameras exhibiting high sensitivity, large dynamic range, and frame rates on the order of MHz, has opened up for temporally and spatially resolved volumetric measurements of extreme dynamics and complexities. The aim of this article is to present selected important laser-based techniques for gas-phase diagnostics focusing on their applications in combustion and aerospace engineering. Applicable laser-based techniques for investigations of turbulent flows and combustion such as planar laser-induced fluorescence, Raman and Rayleigh scattering, coherent anti-Stokes Raman scattering, laser-induced grating scattering, particle image velocimetry, laser Doppler anemometry, and tomographic imaging are reviewed and described with some background physics. In addition, demands on instrumentation are further discussed to give insight in the possibilities that are offered by laser flow diagnostics.

  11. Imaging nuclear medicine techniques for diagnostic evaluation of arterial hypertension. Bildgebende nuklearmedizinische Diagnostik bei arterieller Hypertonie

    Energy Technology Data Exchange (ETDEWEB)

    Eisenberg, B M; Linss, G

    1989-01-01

    Arterial hypertension may be caused by a malfunction of organs and in turn may lead to secondary organic lesions. Modern diagnostic nuclear medicine is applied for function studies in order to detect or exclude secondary hypertension and functional or perfusion disturbances due to hypertension, or to assess and follow up hemodynamic conditions and cardiac functions prior to and during therapy. The article presents a survey of imaging diagnostic nuclear medicine techniques for the eamination of the heart, the brain, the kidneys and endocrine glands in patients with arterial hypertension, discussing the methods with a view to obtainable information, limits of detection, and indications. (orig.).

  12. ICF implosion hotspot ion temperature diagnostic techniques based on neutron time-of-flight method

    International Nuclear Information System (INIS)

    Tang Qi; Song Zifeng; Chen Jiabin; Zhan Xiayu

    2013-01-01

    Ion temperature of implosion hotspot is a very important parameter for inertial confinement fusion. It reflects the energy level of the hotspot, and it is very sensitive to implosion symmetry and implosion speed. ICF implosion hotspot ion temperature diagnostic techniques based on neutron time-of-flight method were described. A neutron TOF spectrometer was developed using a ultrafast plastic scintillator as the neutron detector. Time response of the spectrometer has 1.1 ns FWHM and 0.5 ns rising time. TOF spectrum resolving method based on deconvolution and low pass filter was illuminated. Implosion hotspot ion temperature in low neutron yield and low ion temperature condition at Shenguang-Ⅲ facility was acquired using the diagnostic techniques. (authors)

  13. Electrical-Based Diagnostic Techniques for Assessing Insulation Condition in Aged Transformers

    Directory of Open Access Journals (Sweden)

    Issouf Fofana

    2016-08-01

    Full Text Available The condition of the internal cellulosic paper and oil insulation are of concern for the performance of power transformers. Over the years, a number of methods have been developed to diagnose and monitor the degradation/aging of the transformer internal insulation system. Some of this degradation/aging can be assessed from electrical responses. Currently there are a variety of electrical-based diagnostic techniques available for insulation condition monitoring of power transformers. In most cases, the electrical signals being monitored are due to mechanical or electric changes caused by physical changes in resistivity, inductance or capacitance, moisture, contamination or aging by-products in the insulation. This paper presents a description of commonly used and modern electrical-based diagnostic techniques along with their interpretation schemes.

  14. MR cholangiopancreatography: prospective comparison of a breath-hold 2D projection technique with diagnostic ERCP

    International Nuclear Information System (INIS)

    Lomas, D.J.; Bearcroft, P.W.P.; Gimson, A.E.

    1999-01-01

    The aim of this study was to compare prospectively a breath-hold projection magnetic resonance cholangiopancreatography (MRCP) technique with diagnostic endoscopic retrograde cholangiopancreatography (ERCP). Seventy-six patients with suspected strictures or choledocholithiasis were referred for MRCP and subsequent ERCP examination, which were performed within 4 h of each other. The MRCP technique was performed using fat-suppressed rapid acquisition with relaxation enhancement (RARE) projection images obtained in standardised planes with additional targeted projections as required by the supervising radiologist. Two radiologists (in consensus) assessed the MRCP results prospectively and independently for the presence of bile duct calculi, strictures, non-specific biliary dilatation and pancreatic duct dilatation, and recorded a single primary diagnosis. The ERCP was assessed prospectively and independently by a single endoscopist and used as a gold standard for comparison with MRCP. Diagnostic agreement was assessed by the Kappa statistic. The MRCP technique failed in two patients and ERCP in five. In the remaining 69 referrals ERCP demonstrated normal findings in 23 cases, strictures in 19 cases, choledocholithiasis in 9 cases, non-specific biliary dilatation in 14 cases and chronic pancreatitis in 4 cases. The MRCP technique correctly demonstrated 22 of 23 normal cases, 19 strictures with one false positive (sensitivity 100 %, specificity 98 %), all 9 cases of choledocholithiasis with two false positives (sensitivity 100 %, specificity 97 %), 12 of 14 cases of non-specific biliary dilatation and only 1 of 4 cases of chronic pancreatitis. There was overall good agreement for diagnosis based on a kappa value of 0.88. Breath-hold projection MRCP can provide non-invasively comparable diagnostic information to diagnostic ERCP for suspected choledocholithiasis and biliary strictures and may allow more selective use of therapeutic ERCP. (orig.)

  15. Plasma diagnostic techniques in thermal-barrier tandem-mirror fusion experiments

    International Nuclear Information System (INIS)

    Silver, E.H.; Clauser, J.F.; Carter, M.R.; Failor, B.H.; Foote, J.H.; Hornady, R.S.; James, R.A.; Lasnier, C.J.; Perkins, D.E.

    1986-01-01

    We review two classes of plasma diagnostic techniques used in thermal-barrier tandem-mirror fusion experiments. The emphasis of the first class is to study mirror-trapped electrons at the thermal-barrier location. The focus of the second class is to measure the spatial and temporal behavior of the plasma space potential at various axial locations. The design and operation of the instruments in these two categories are discussed and data that are representative of their performance is presented

  16. The evaluation of the irradiation of medical team in critical X-ray diagnostic techniques

    Energy Technology Data Exchange (ETDEWEB)

    Markovic, S; Pavlovic, R [Inst. of Nuclear Science Vinca, Belgrade (Yugoslavia). Radiation and Environmental Protection Lab.; Boreli, F [Fac. of Electrical Engineering, Belgrade (Yugoslavia)

    1996-12-31

    A good realized assessment of the irradiation for any exposed group of population serves as the base for the radiation protection measures (emergency radiation preparedness, radiation protection optimization etc.). This is especially important, by the radiation protection point of view, in contrast X-ray diagnostic techniques - angiographies. This paper presents the way for the realization of the medical team irradiation assessment, based on originally derived simple equations for the scattered radiation field around patient. (author) 1 fig., 3 figs.

  17. Optical diagnostics of vascular reactions triggered by weak allergens using laser speckle-contrast imaging technique

    International Nuclear Information System (INIS)

    Kuznetsov, Yu L; Kalchenko, V V; Astaf'eva, N G; Meglinski, I V

    2014-01-01

    The capability of using the laser speckle contrast imaging technique with a long exposure time for visualisation of primary acute skin vascular reactions caused by a topical application of a weak contact allergen is considered. The method is shown to provide efficient and accurate detection of irritant-induced primary acute vascular reactions of skin. The presented technique possesses a high potential in everyday diagnostic practice, preclinical studies, as well as in the prognosis of skin reactions to the interaction with potentially allergenic materials. (laser biophotonics)

  18. Optical diagnostics of vascular reactions triggered by weak allergens using laser speckle-contrast imaging technique

    Energy Technology Data Exchange (ETDEWEB)

    Kuznetsov, Yu L; Kalchenko, V V [Department of Veterinary Resources, Weizmann Institute of Science, Rehovot, 76100 (Israel); Astaf' eva, N G [V.I.Razumovsky Saratov State Medical University, Saratov (Russian Federation); Meglinski, I V [N.G. Chernyshevsky Saratov State University, Saratov (Russian Federation)

    2014-08-31

    The capability of using the laser speckle contrast imaging technique with a long exposure time for visualisation of primary acute skin vascular reactions caused by a topical application of a weak contact allergen is considered. The method is shown to provide efficient and accurate detection of irritant-induced primary acute vascular reactions of skin. The presented technique possesses a high potential in everyday diagnostic practice, preclinical studies, as well as in the prognosis of skin reactions to the interaction with potentially allergenic materials. (laser biophotonics)

  19. Optimized design of shields for diagnostic X rays with NCRP 147 technique

    International Nuclear Information System (INIS)

    Gama T, G.

    2006-01-01

    A comparison among the design techniques of shielding for X-ray diagnostic rooms with the NCRP 49 (1976) report technique, AAPM 39 (1993) Y the one of the NCRP 147 (2005) technique. The designs correspond to a room of conventional X-rays, one of fluoroscopy, one of tomography Y one of mammography. In all the cases it demonstrates that the NCRP 49 technique overestimate the shieldings. The causes of the overestimation of the NCRP 49 can be attributed to: a) high values of the work charge that don't consider the spectral fluence of the photons that are present in each room, b) to the differences in the values of the kerma in air without attenuation for the dispersed primary radiation Y of leakage among both reports. (Author)

  20. Consideration on the diagnostic ability of various imaging techniques in relation to renal tumor

    International Nuclear Information System (INIS)

    Ike, Katsushi

    1984-01-01

    Radiological diagnosis of renal tumors is being improved with the increased imaging accuracy which has resulted from advancement in the various equipment used and improvement in techniques. However, at the clinical level, diagnostic procedures based on the characteristics of the delineated images are not yet established and the diverse diagnostic procedures are being conducted currently in a stereotyped manner. In this study, the images of 61 cases diagnosed as renal tumor were analysed retrospectively with the purpose of establishing the imaging accuracy, capacity for diagnosis based on image characteristics and a subseguent proper diagnostic procedure. It was found that CT and Angio gave similar diagnostic accuracy. It was further revealed that US images enabled to differentiate renal tumors from the more commonly experienced renal cystic disease. For determination of tunica involucrum infiltration, which is essential to diagnose Stage I and II renal tumors, CT was proved to be superior to Angio. CT and US were also to be so in the determination of metastasis to para-aortic lymph nodes which is a Stage III criterion. In recent years, CT and US imaging accuracies have increased, hence the improvement in the capacity to diagnose non-observable renal tumors is highly expected. (author)

  1. TOF technique for laser-driven proton beam diagnostics for the ELIMED beamline

    International Nuclear Information System (INIS)

    Milluzzo, G.; Scuderi, V.; Amico, A.G.; Cirrone, G.A.P.; Cuttone, G.; Larosa, G.; Leanza, R.; Petringa, G.; Pipek, J.; Romano, F.; Napoli, M. De; Dostal, J.; Margarone, D.; Schillaci, F.; Velyhan, A.

    2017-01-01

    The Time of Flight (TOF) method for laser-driven ion beam diagnostics has been extensively investigated so far for low energy ion diagnostics and several works, reported in literature [1,2], have shown its efficiency in the measurement of particle beam characteristics such as ion species, energy spectrum and current. Moreover, such technique allows obtaining a shot-to-shot on-line monitoring of optically accelerated particles, necessary to control the reproducibility of the accelerated beam and to deliver a beam suitable for any kind of applications. For this reason, the ELIMED beamline [3,4], which will be entirely developed at INFN-LNS and installed in 2017 within the ion beamline ELIMAIA (ELI Multidisciplinary Applications of laser-Ion Acceleration) experimental hall at ELI-Beamlines in Prague, will be equipped with an on-line diagnostics system composed by silicon carbide and diamond detectors, using the TOF technique. In this contribution, the procedure developed for TOF signal analysis will be briefly reported.

  2. Vibration monitoring/diagnostic techniques, as applied to reactor coolant pumps

    International Nuclear Information System (INIS)

    Sculthorpe, B.R.; Johnson, K.M.

    1986-01-01

    With the increased awareness of reactor coolant pump (RCP) cracked shafts, brought about by the catastrophic shaft failure at Crystal River number3, Florida Power and Light Company, in conjunction with Bently Nevada Corporation, undertook a test program at St. Lucie Nuclear Unit number2, to confirm the integrity of all four RCP pump shafts. Reactor coolant pumps play a major roll in the operation of nuclear-powered generation facilities. The time required to disassemble and physically inspect a single RCP shaft would be lengthy, monetarily costly to the utility and its customers, and cause possible unnecessary man-rem exposure to plant personnel. When properly applied, vibration instrumentation can increase unit availability/reliability, as well as provide enhanced diagnostic capability. This paper reviews monitoring benefits and diagnostic techniques applicable to RCPs/motor drives

  3. PREFACE: IX International Conference on Modern Techniques of Plasma Diagnostics and their Application

    Science.gov (United States)

    Savjolov, A. S.; Dodulad, E. I.

    2016-01-01

    The IX Conference on ''Modern Techniques of Plasma Diagnosis and their Application'' was held on 5 - 7 November, 2014 at National Research Nuclear University MEPhI (NRNU MEPhI). The goal of the conference was an exchange of information on both high-temperature and low-temperature plasma diagnostics as well as deliberation and analysis of various diagnostic techniques and their applicability in science, industry, ecology, medicine and other fields. The Conference also provided young scientists from scientific centres and universities engaged in plasma diagnostics with an opportunity to attend the lectures given by the leading specialists in this field as well as present their own results and findings. The first workshop titled ''Modern problems of plasma diagnostics and their application for control of chemicals and the environment'' took place at Moscow Engineering and Physics Institute (MEPhI) in June 1998 with the support of the Section on Diagnostics of the Council of Russian Academic of Science on Plasma Physics and since then these forums have been held at MEPhI every two years. In 2008 the workshop was assigned a conference status. More than 150 specialists on plasma diagnostics and students took part in the last conference. They represented leading Russian scientific centres (such as Troitsk Institute of Innovative and Thermonuclear Research, National Research Centre ''Kurchatov Institute'', Russian Federal Nuclear Centre - All-Russian Scientific Research Institute of Experimental Physics and others) and universities from Belarus, Ukraine, Germany, USA, Belgium and Sweden. About 30 reports were made by young researchers, students and post-graduate students. All presentations during the conference were broadcasted online over the internet with viewers in Moscow, Prague, St. Petersburgh and other cities. The Conference was held within the framework of the Centre of Plasma, Laser Research and Technology supported by MEPhI Academic Excellence Project (Russian

  4. Evidence-based medical research on diagnostic criteria and screening technique of vascular mild cognitive impairment

    Directory of Open Access Journals (Sweden)

    Xia-wei LIU

    2015-07-01

    Full Text Available Background Vascular mild cognitive impairment (VaMCI is the prodromal syndrome of vascular dementia (VaD and key target for drug treatment. There is controversy over the diagnostic criteria and screening tools of VaMCI, which affects its clinical diagnosis. This paper aims to explore the clinical features, diagnostic criteria and screening technique of VaMCI.  Methods Taking "vascular mild cognitive impairment OR vascular cognitive impairment no dementia" as retrieval terms, search in PubMed database from January 1997 to March 2015 and screen relevant literatures concerning VaMCI. According to Guidance for the Preparation of Neurological Management Guidelines revised by European Federation of Neurological Societies (EFNS in 2004, evidence grading was performed on literatures. Results A total of 32 literatures in English were selected according to inclusion and exclusion criteria, including 3 guidelines and consensus and 29 clinical studies. Seven literatures (2 on Level Ⅰ, 5 on Level Ⅱ studied on neuropsychological features in VaMCI patients and found reduced processing speed and executive function impairment were main features. Two literatures reported the diagnostic criteria of VaMCI, including VaMCI criteria published by American Heart Association (AHA/American Stroke Association (ASA in 2011 and "Diagnostic Criteria for Vascular Cognitive Disorders" published by International Society for Vascular Behavioral and Cognitive Disorders (VASCOG in 2014. Fifteen literatures (4 on LevelⅠ, 11 on Level Ⅱ described the diagnostic criteria of VaMCI used in clinical research, from which 6 operational diagnostic items were extracted. Fourteen literatures (4 on Level Ⅰ, 10 on Level Ⅱ described neuropsychological assessment tools for VaMCI screening, and found the 5-minute protocol recommended by National Institute of Neurological Disorders and Stroke-Canadian Stroke Network (NINDS-CSN was being good consistency with other neuropsychological

  5. Imaging techniques used in the diagnostic workup of acute venous thromboembolic disease.

    Science.gov (United States)

    Tilve-Gómez, A; Rodríguez-Fernández, P; Trillo-Fandiño, L; Plasencia-Martínez, J M

    Early diagnosis is one of the most important factors affecting the prognosis of pulmonary embolism (PE); however, the clinical presentation of PE is often very unspecific and it can simulate other diseases. For these reasons, imaging tests, especially computed tomography angiography (CTA) of the pulmonary arteries, have become the keystone in the diagnostic workup of PE. The wide availability and high diagnostic performance of pulmonary CTA has led to an increase in the number of examinations done and a consequent increase in the population's exposure to radiation and iodinated contrast material. Thus, other techniques such as scintigraphy and venous ultrasonography of the lower limbs, although less accurate, continue to be used in certain circumstances, and optimized protocols have been developed for CTA to reduce the dose of radiation (by decreasing the kilovoltage) and the dose of contrast agents. We describe the technical characteristics and interpretation of the findings for each imaging technique used to diagnose PE and discuss their advantages and limitations; this knowledge will help the best technique to be chosen for each case. Finally, we comment on some data about the increased use of CTA, its clinical repercussions, its "overuse", and doubts about its cost-effectiveness. Copyright © 2016 SERAM. Publicado por Elsevier España, S.L.U. All rights reserved.

  6. Picosecond high power laser systems and picosecond diagnostic technique in laser produced plasma

    International Nuclear Information System (INIS)

    Kuroda, Hiroto; Masuko, H.; Maekawa, Shigeru; Suzuki, Yoshiji; Sugiyama, Masaru.

    1979-01-01

    Highly repetitive, high power YAG and Glass laser systems have been developed and been successfully used for the studies of laser-plasma interactions. Various picosecond diagnostic techniques have been developed for such purposes in the regions from optical to X-ray frequency. Recently highly sensitive X-ray (1 - 10 KeV) streak camera for highly repetitive operations have been developed. Preliminary experiment shows the achievement of 28ps temporal resolution (100μm slit) and good sensitivity with detectable minimum number of 10E3-1KeV photons/shot/slit area. (author)

  7. Iterative reconstruction technique with reduced volume CT dose index: diagnostic accuracy in pediatric acute appendicitis

    International Nuclear Information System (INIS)

    Didier, Ryne A.; Vajtai, Petra L.; Hopkins, Katharine L.

    2015-01-01

    Iterative reconstruction technique has been proposed as a means of reducing patient radiation dose in pediatric CT. Yet, the effect of such reductions on diagnostic accuracy has not been thoroughly evaluated. This study compares accuracy of diagnosing pediatric acute appendicitis using contrast-enhanced abdominopelvic CT scans performed with traditional pediatric weight-based protocols and filtered back projection reconstruction vs. a filtered back projection/iterative reconstruction technique blend with reduced volume CT dose index (CTDI vol ). Results of pediatric contrast-enhanced abdominopelvic CT scans done for pain and/or suspected appendicitis were reviewed in two groups: A, 192 scans performed with the hospital's established weight-based CT protocols and filtered back projection reconstruction; B, 194 scans performed with iterative reconstruction technique and reduced CTDI vol . Reduced CTDI vol was achieved primarily by reductions in effective tube current-time product (mAs eff ) and tube peak kilovoltage (kVp). CT interpretation was correlated with clinical follow-up and/or surgical pathology. CTDI vol , size-specific dose estimates (SSDE) and performance characteristics of the two CT techniques were then compared. Between groups A and B, mean CTDI vol was reduced by 45%, and mean SSDE was reduced by 46%. Sensitivity, specificity and diagnostic accuracy were 96%, 97% and 96% in group A vs. 100%, 99% and 99% in group B. Accuracy in diagnosing pediatric acute appendicitis was maintained in contrast-enhanced abdominopelvic CT scans that incorporated iterative reconstruction technique, despite reductions in mean CTDI vol and SSDE by nearly half as compared to the hospital's traditional weight-based protocols. (orig.)

  8. Iterative reconstruction technique with reduced volume CT dose index: diagnostic accuracy in pediatric acute appendicitis

    Energy Technology Data Exchange (ETDEWEB)

    Didier, Ryne A. [Oregon Health and Science University, Department of Diagnostic Radiology, DC7R, Portland, OR (United States); Vajtai, Petra L. [Oregon Health and Science University, Department of Pediatrics, Portland, OR (United States); Oregon Health and Science University, Department of Diagnostic Radiology, DC7R, Portland, OR (United States); Hopkins, Katharine L. [Oregon Health and Science University, Department of Diagnostic Radiology, DC7R, Portland, OR (United States); Oregon Health and Science University, Department of Pediatrics, Portland, OR (United States)

    2014-07-05

    Iterative reconstruction technique has been proposed as a means of reducing patient radiation dose in pediatric CT. Yet, the effect of such reductions on diagnostic accuracy has not been thoroughly evaluated. This study compares accuracy of diagnosing pediatric acute appendicitis using contrast-enhanced abdominopelvic CT scans performed with traditional pediatric weight-based protocols and filtered back projection reconstruction vs. a filtered back projection/iterative reconstruction technique blend with reduced volume CT dose index (CTDI{sub vol}). Results of pediatric contrast-enhanced abdominopelvic CT scans done for pain and/or suspected appendicitis were reviewed in two groups: A, 192 scans performed with the hospital's established weight-based CT protocols and filtered back projection reconstruction; B, 194 scans performed with iterative reconstruction technique and reduced CTDI{sub vol}. Reduced CTDI{sub vol} was achieved primarily by reductions in effective tube current-time product (mAs{sub eff}) and tube peak kilovoltage (kVp). CT interpretation was correlated with clinical follow-up and/or surgical pathology. CTDI{sub vol}, size-specific dose estimates (SSDE) and performance characteristics of the two CT techniques were then compared. Between groups A and B, mean CTDI{sub vol} was reduced by 45%, and mean SSDE was reduced by 46%. Sensitivity, specificity and diagnostic accuracy were 96%, 97% and 96% in group A vs. 100%, 99% and 99% in group B. Accuracy in diagnosing pediatric acute appendicitis was maintained in contrast-enhanced abdominopelvic CT scans that incorporated iterative reconstruction technique, despite reductions in mean CTDI{sub vol} and SSDE by nearly half as compared to the hospital's traditional weight-based protocols. (orig.)

  9. Multimodal imaging of vascular network and blood microcirculation by optical diagnostic techniques

    International Nuclear Information System (INIS)

    Kuznetsov, Yu L; Kalchenko, V V; Meglinski, I V

    2011-01-01

    We present a multimodal optical diagnostic approach for simultaneous non-invasive in vivo imaging of blood and lymphatic microvessels, utilising a combined use of fluorescence intravital microscopy and a method of dynamic light scattering. This approach makes it possible to renounce the use of fluorescent markers for visualisation of blood vessels and, therefore, significantly (tenfold) reduce the toxicity of the technique and minimise side effects caused by the use of contrast fluorescent markers. We demonstrate that along with the ability to obtain images of lymph and blood microvessels with a high spatial resolution, current multimodal approach allows one to observe in real time permeability of blood vessels. This technique appears to be promising in physiology studies of blood vessels, and especially in the study of peripheral cardiovascular system in vivo. (optical technologies in biophysics and medicine)

  10. Application of RNB for high sensitive wear diagnostics in medicine technique and industry

    International Nuclear Information System (INIS)

    Fehsenfeld, P.; Eifrig, C.; Kubat, R.

    2002-01-01

    The RTM--Radionuclide Technique in Mechanical engineering--is now extended to the solution of world wide problems in medicine technique (prosthetics), and in development of modern materials (synthetic materials, ceramics, hard coatings, etc.) and their industrial application. RNB--Radioactive Nuclear Beams of 7 Be or 22 Na--may enable the required extreme thin radioactive surface labeling (several micrometers) of synthetic materials for wear measurements without producing radiation damages of influence to the wear properties of the material. The function principle and special properties of the RTM on-line wear diagnostics and its components, the measurement methods, the radioactive surface labeling, and the measurement instruments are explained. The quality features of a 7 Be and 22 Na-beam for RTM application are specified

  11. Development of a 2D temperature measurement technique for combustion diagnostics using 2-line atomic fluorescence

    Energy Technology Data Exchange (ETDEWEB)

    Engstroem, Johan

    2001-01-01

    The present thesis is concerned with the development and application of a novel planar laser-induced fluorescence (PLIF) technique for temperature measurements in a variety of combusting flows. Accurate measurement of temperature is an essential task in combustion diagnostics, since temperature is one of the most fundamental quantities for the characterization of combustion processes. The technique is based on two-line atomic fluorescence (TLAF) from small quantities of atomic indium (In) seeded into the fuel. It has been developed from small-scale experiments in laboratory flames to the point where practical combustion systems can be studied. The technique is conceptually simple and reveals temperature information in the post-flame regions. The viability of the technique has been tested in three extreme measurement situations: in spark ignition engine combustion, in ultra-lean combustion situations such as lean burning aero-engine concepts and, finally, in fuel-rich combustion. TLAF was successfully applied in an optical Sl engine using isooctane as fuel. The wide temperature sensitivity, 700 - 3000 K, of the technique using indium atoms allowed measurements over the entire combustion cycle in the engine to be performed. In applications in lean combustion a potential problem caused by the strong oxidation processes of indium atoms was encountered. This limits measurement times due to deposits of absorbing indium oxide on measurement windows. The seeding requirement is a disadvantage of the technique and can be a limitation in some applications. The results from experiments performed in sooting flames are very promising for thermometry measurements in such environments. Absorption by hydrocarbons and other native species was found to be negligible. Since low laser energies and low seeding concentrations could be used, the technique did not, unlike most other incoherent optical thermometry techniques, suffer interferences from LII of soot particles or LIF from PAH

  12. Mining for diagnostic information in body surface potential maps: A comparison of feature selection techniques

    Directory of Open Access Journals (Sweden)

    McCullagh Paul J

    2005-09-01

    Full Text Available Abstract Background In body surface potential mapping, increased spatial sampling is used to allow more accurate detection of a cardiac abnormality. Although diagnostically superior to more conventional electrocardiographic techniques, the perceived complexity of the Body Surface Potential Map (BSPM acquisition process has prohibited its acceptance in clinical practice. For this reason there is an interest in striking a compromise between the minimum number of electrocardiographic recording sites required to sample the maximum electrocardiographic information. Methods In the current study, several techniques widely used in the domains of data mining and knowledge discovery have been employed to mine for diagnostic information in 192 lead BSPMs. In particular, the Single Variable Classifier (SVC based filter and Sequential Forward Selection (SFS based wrapper approaches to feature selection have been implemented and evaluated. Using a set of recordings from 116 subjects, the diagnostic ability of subsets of 3, 6, 9, 12, 24 and 32 electrocardiographic recording sites have been evaluated based on their ability to correctly asses the presence or absence of Myocardial Infarction (MI. Results It was observed that the wrapper approach, using sequential forward selection and a 5 nearest neighbour classifier, was capable of choosing a set of 24 recording sites that could correctly classify 82.8% of BSPMs. Although the filter method performed slightly less favourably, the performance was comparable with a classification accuracy of 79.3%. In addition, experiments were conducted to show how (a features chosen using the wrapper approach were specific to the classifier used in the selection model, and (b lead subsets chosen were not necessarily unique. Conclusion It was concluded that both the filter and wrapper approaches adopted were suitable for guiding the choice of recording sites useful for determining the presence of MI. It should be noted however

  13. A study on the fault diagnostic techniques for reactor internal structures using neutron noise analysis

    International Nuclear Information System (INIS)

    Kim, Tae Ryong; Jeong, Seong Ho; Park, Jin Ho; Park, Jin Suk

    1994-08-01

    The unfavorable phenomena, such as flow induced vibration and aging process in reactor internals, cause degradation of structural integrity and may result in loosing some mechanical binding components which might impact other equipments and components or cause flow blockage. Since these malfunctions and potential failures change reactor noise signal, it is necessary to analyze reactor noise signal for early fault diagnosis in the point of few of safety and plant economics. The objectives of this study are to establish fault diagnostic and TS(thermal shield), and to develop a data acquisition and signal processing software system. In the first year of this study, an analysis technique for the reactor internal vibration using the reactor noise was proposed. With the technique proposed and the reactor noise signals (ex-core neutron and acceleration), the dynamic characteristics of Ulchin-1 reactor internals were obtained, and compared with those of Tricastin-1 which is the prototype of Ulchin-1. In the second year, a PC-based expert system for reactor internals fault diagnosis is developed, which included data acquisition, signal processing, feature extraction function, and represented diagnostic knowledge by the IF-THEN rule. To know the effect of the faults, the reactor internals of Ulchin-1 is modeled using FEM and simulated with an artificial defect given in the hold-down spring. Trend in the dynamic characteristics of reactor internals is also observed during one fuel cycle to know the effect of boron concentration. 100 figs, 7 tabs, 18 refs. (Author)

  14. The Role of Flow Diagnostic Techniques in Fan and Open Rotor Noise Modeling

    Science.gov (United States)

    Envia, Edmane

    2016-01-01

    A principal source of turbomachinery noise is the interaction of the rotating and stationary blade rows with the perturbations in the airstream through the engine. As such, a lot of research has been devoted to the study of the turbomachinery noise generation mechanisms. This is particularly true of fan and open rotors, both of which are the major contributors to the overall noise output of modern aircraft engines. Much of the research in fan and open rotor noise has been focused on developing theoretical models for predicting their noise characteristics. These models, which run the gamut from the semi-empirical to fully computational ones, are, in one form or another, informed by the description of the unsteady flow-field in which the propulsors (i.e., the fan and open rotors) operate. Not surprisingly, the fidelity of the theoretical models is dependent, to a large extent, on capturing the nuances of the unsteady flowfield that have a direct role in the noise generation process. As such, flow diagnostic techniques have proven to be indispensible in identifying the shortcoming of theoretical models and in helping to improve them. This presentation will provide a few examples of the role of flow diagnostic techniques in assessing the fidelity and robustness of the fan and open rotor noise prediction models.

  15. [Application of molecular diagnostic techniques in precision medicine of personalized treatment for colorectal cancer].

    Science.gov (United States)

    Fu, Ji; Lin, Guole

    2016-01-01

    Precision medicine is to customize the treatment options for individual patient based on the personal genome information. Colorectal cancer (CRC) is one of the most common cancer worldwide. Molecular heterogeneity of CRC, which includes the MSI phenotype, hypermutation phenotype, and their relationship with clinical preferences, is believed to be one of the main factors responsible for the considerable variability in treatment response. The development of powerful next-generation sequencing (NGS) technologies allows us to further understand the biological behavior of colorectal cancer, and to analyze the prognosis and chemotherapeutic drug reactions by molecular diagnostic techniques, which can guide the clinical treatment. This paper will introduce the new findings in this field. Meanwhile we integrate the new progress of key pathways including EGFR, RAS, PI3K/AKT and VEGF, and the experience in selective patients through associated molecular diagnostic screening who gain better efficacy after target therapy. The technique for detecting circulating tumor DNA (ctDNA) is introduced here as well, which can identify patients with high risk for recurrence, and demonstrate the risk of chemotherapy resistance. Mechanism of tumor drug resistance may be revealed by dynamic observation of gene alteration during treatment.

  16. Evaluation of Temporal Diagnostic Techniques for Two-Bunch Facet Beam

    Energy Technology Data Exchange (ETDEWEB)

    Litos, M.D.; Bionta, M.R.; Dolgashev, V.A.; England, R.J.; Fritz, D.; Gilevich, S.; Hering, Ph.; Hogan, M.J.; /SLAC

    2011-08-19

    Three temporal diagnostic techniques are considered for use in the FACET facility at SLAC, which will incorporate a unique two-bunch beam for plasma wakefield acceleration experiments. The results of these experiments will depend strongly on the the inter-bunch spacing as well as the longitudinal profiles of the two bunches. A reliable, singleshot, high resolution measurement of the beam's temporal profile is necessary to fully quantify the physical mechanisms underlying the beam driven plasma wakefield acceleration. In this study we show that a transverse deflecting cavity is the diagnostic which best meets our criteria. Based on our laboratory testing, numerical calculations, and simulations of the three single-shot temporal diagnostic devices, the X-band TCAV system is the best candidate for resolving FACET's two-bunch beam, with an estimated resolution of 7 {micro}m. Both the S-band TCAV system and the EO system could resolve the peak-to-peak separation of the two bunches in the FACET beam with estimated resolutions of 25 {micro}m and 30 {micro}m, respectively, but would be unable to resolve the temporal profiles of the individual bunches themselves. Because the TCAV signal is more easily interpreted and because the reliability of the EO system is less well known, however, the S-band TCAV system would be the next preferred option after the X-band TCAV system. The Fesca-200 streak camera, though simple, compact, and reliable, is unable to achieve a resolution that would be of use to FACET.

  17. Upgrades of Diagnostic Techniques and Technologies for JET next D-T Campaigns

    Energy Technology Data Exchange (ETDEWEB)

    Murari, Andrea [Consorzio RFX - CNR, ENEA, INFN, Universita di Padova, Acciaierie Venete SpA,Corso Stati Uniti 4, 35127 Padova (Italy)

    2015-07-01

    . With regard to the fusion products, JET now can deploy a consistent set of techniques to measure the neutron yield and neutron spectra and to diagnose the fast particles. A full calibration of the neutron diagnostics with a 14 MeV source is being considered, after the recent very successful calibration for the 2.45 MeV neutrons. Vertical and horizontal lines of sight are foreseen for neutron and gamma spectrometry, in order to better determine the thermal neutron yield and to separate the trapped and passing components of the alphas. Various gamma ray spectrometers are being developed to cover all the various operational scenarios, from trace tritium to 50-50 D-T operation. The redistribution of the alphas will be measured with the gamma ray cameras, recently upgraded with full digital electronics; new detectors are being considered to bring the time resolution of the system in the ten of ms range. The lost alphas will also be diagnosed with improved spatial and temporal resolution, using Faraday cups and a scintillator probe. From a technological perspective, the D-T campaign will provide a unique opportunity to test ITER relevant technologies. From radiation hard detectors, for example Hall probes, to neutron absorbers and to shielding concepts, the potential of various solutions in a realistic 14 MeV radiation field will be assessed. The effects of neutrons and gamma on ancillary technologies and systems, such as fibre optics and electronics circuits, are also expected to be sufficiently high to derive useful information about the competitive advantage of various alternatives.

  18. A novel non-invasive diagnostic sampling technique for cutaneous leishmaniasis.

    Directory of Open Access Journals (Sweden)

    Yasaman Taslimi

    2017-07-01

    Full Text Available Accurate diagnosis of cutaneous leishmaniasis (CL is important for chemotherapy and epidemiological studies. Common approaches for Leishmania detection involve the invasive collection of specimens for direct identification of amastigotes by microscopy and the culturing of promastigotes from infected tissues. Although these techniques are highly specific, they require highly skilled health workers and have the inherent risks of all invasive procedures, such as pain and risk of bacterial and fungal super-infection. Therefore, it is essential to reduce discomfort, potential infection and scarring caused by invasive diagnostic approaches especially for children. In this report, we present a novel non-invasive method, that is painless, rapid and user-friendly, using sequential tape strips for sampling and isolation of DNA from the surface of active and healed skin lesions of CL patients. A total of 119 patients suspected of suffering from cutaneous leishmaniasis with different clinical manifestations were recruited and samples were collected both from their lesions and from uninfected areas. In addition, 15 fungal-infected lesions and 54 areas of healthy skin were examined. The duration of sampling is short (less than one minute and species identification by PCR is highly specific and sensitive. The sequential tape stripping sampling method is a sensitive, non-invasive and cost-effective alternative to traditional diagnostic assays and it is suitable for field studies as well as for use in health care centers.

  19. Diagnostic evaluation of rolling behavior in ball bearings by ultrasonic technique

    International Nuclear Information System (INIS)

    Wakabayashi, T

    2012-01-01

    Failures of machines having rotating parts are mostly caused by damage to bearings and there exist increasing demands for detecting damaged bearings at an early stage. However, conventional diagnostic methods, such as measuring temperature and observing vibration, have found difficulties in performing the early detection, so that more advanced diagnosis is necessary. This study therefore applies an ultrasonic technique as an advanced diagnostic method to bearing life tests. Ultrasonic wave pulses (UWP) emitted from a piezoelectric UWP generator can partially reflect from the interfaces of contact zones within the housing and the bearing with regard to the different acoustic impedance between a solid-to-solid contact and a contact dominated by some fluid layers. Hence, the intensity of the resultant UWP echoes can be determined by the real contact area formed at the interfaces. The experimental results of UWP echoes under the different operating conditions have demonstrated that the time intervals between peaks of UWP echoes varied in accordance with the movement of rolling balls and the lubricating phenomena in bearings. This behavior has further suggested the possibility of the early detection of abnormalities in ball bearings by using the variation in UWP echoes.

  20. Evaluation of diagnostic technique for degradation of low-voltage electric cables with silicone rubber insulator

    International Nuclear Information System (INIS)

    Mikami, Masao

    2005-01-01

    As a part of countermeasures against ageing problems of nuclear power plants, it is requested to establish non-destructive diagnostic technique for their degradation of low voltage electric cables and assessment standard of their life. Having aimed at investigating the degradation of low-voltage electric cable with silicone rubber insulator, change of its surface hardness at elevated temperature were measured by indenter modules. Moreover, we also measured the elongation at break, which is regarded as general degradation index of electric cables, and the surface hardness with a micro hardness meter. Consequently, it is seen that the indenter modulus measurement is (1) capable to obtain general feature of the thermal degradation of silicone rubber insulator, (2) applicable to diagnose the degree of degradation of the electric cable by converting the result to elongation at break, (3) well correlated with the hardness measurement of the electric cable with the micro hardness meter. (author)

  1. Uncertainty Management for Diagnostics and Prognostics of Batteries using Bayesian Techniques

    Science.gov (United States)

    Saha, Bhaskar; Goebel, kai

    2007-01-01

    Uncertainty management has always been the key hurdle faced by diagnostics and prognostics algorithms. A Bayesian treatment of this problem provides an elegant and theoretically sound approach to the modern Condition- Based Maintenance (CBM)/Prognostic Health Management (PHM) paradigm. The application of the Bayesian techniques to regression and classification in the form of Relevance Vector Machine (RVM), and to state estimation as in Particle Filters (PF), provides a powerful tool to integrate the diagnosis and prognosis of battery health. The RVM, which is a Bayesian treatment of the Support Vector Machine (SVM), is used for model identification, while the PF framework uses the learnt model, statistical estimates of noise and anticipated operational conditions to provide estimates of remaining useful life (RUL) in the form of a probability density function (PDF). This type of prognostics generates a significant value addition to the management of any operation involving electrical systems.

  2. IERIAS: inference engine for reactor accident diagnostic system using knowledge engineering technique

    International Nuclear Information System (INIS)

    Yokobayashi, Masao; Yoshida, Kazuo; Kohsaka, Atsuo; Yamamoto, Minoru.

    1984-11-01

    This report describes an inference engine IERIAS which has been devoloped for a diagnostic system to identify the cause and type of an abnormal transient of a reactor plant. This system using knowledge engineering technique consists of a knowledge base and an inference engine. The inference engine IERIAS is designed so as to treat time-varying data of a plant. The major features of IERIAS are ; (1) histroy of transients can be treated, (2) knowledge base can be divided into some knowledge units, (3) program language UTILISP is used which is suitable for symbolic data manipulation. Inference was made using IERIAS with a knowledge base which was created from simulated results of various transients by a PWR plant simulator. The results showed a good applicability of IERIAS for reactor diagnosis. (author)

  3. New Diagnostic, Launch and Model Control Techniques in the NASA Ames HFFAF Ballistic Range

    Science.gov (United States)

    Bogdanoff, David W.

    2012-01-01

    This report presents new diagnostic, launch and model control techniques used in the NASA Ames HFFAF ballistic range. High speed movies were used to view the sabot separation process and the passage of the model through the model splap paper. Cavities in the rear of the sabot, to catch the muzzle blast of the gun, were used to control sabot finger separation angles and distances. Inserts were installed in the powder chamber to greatly reduce the ullage volume (empty space) in the chamber. This resulted in much more complete and repeatable combustion of the powder and hence, in much more repeatable muzzle velocities. Sheets of paper or cardstock, impacting one half of the model, were used to control the amplitudes of the model pitch oscillations.

  4. Probabilistic techniques using Monte Carlo sampling for multi- component system diagnostics

    International Nuclear Information System (INIS)

    Aumeier, S.E.; Lee, J.C.; Akcasu, A.Z.

    1995-01-01

    We outline the structure of a new approach at multi-component system fault diagnostics which utilizes detailed system simulation models, uncertain system observation data, statistical knowledge of system parameters, expert opinion, and component reliability data in an effort to identify incipient component performance degradations of arbitrary number and magnitude. The technique involves the use of multiple adaptive Kalman filters for fault estimation, the results of which are screened using standard hypothesis testing procedures to define a set of component events that could have transpired. Latin Hypercube sample each of these feasible component events in terms of uncertain component reliability data and filter estimates. The capabilities of the procedure are demonstrated through the analysis of a simulated small magnitude binary component fault in a boiling water reactor balance of plant. The results show that the procedure has the potential to be a very effective tool for incipient component fault diagnosis

  5. Reducing beam shaper alignment complexity: diagnostic techniques for alignment and tuning

    Science.gov (United States)

    Lizotte, Todd E.

    2011-10-01

    Safe and efficient optical alignment is a critical requirement for industrial laser systems used in a high volume manufacturing environment. Of specific interest is the development of techniques to align beam shaping optics within a beam line; having the ability to instantly verify by a qualitative means that each element is in its proper position as the beam shaper module is being aligned. There is a need to reduce these types of alignment techniques down to a level where even a newbie to optical alignment will be able to complete the task. Couple this alignment need with the fact that most laser system manufacturers ship their products worldwide and the introduction of a new set of variables including cultural and language barriers, makes this a top priority for manufacturers. Tools and methodologies for alignment of complex optical systems need to be able to cross these barriers to ensure the highest degree of up time and reduce the cost of maintenance on the production floor. Customers worldwide, who purchase production laser equipment, understand that the majority of costs to a manufacturing facility is spent on system maintenance and is typically the largest single controllable expenditure in a production plant. This desire to reduce costs is driving the trend these days towards predictive and proactive, not reactive maintenance of laser based optical beam delivery systems [10]. With proper diagnostic tools, laser system developers can develop proactive approaches to reduce system down time, safe guard operational performance and reduce premature or catastrophic optics failures. Obviously analytical data will provide quantifiable performance standards which are more precise than qualitative standards, but each have a role in determining overall optical system performance [10]. This paper will discuss the use of film and fluorescent mirror devices as diagnostic tools for beam shaper module alignment off line or in-situ. The paper will also provide an overview

  6. Sportsmen’s Groin—Diagnostic Approach and Treatment With the Minimal Repair Technique

    Science.gov (United States)

    Muschaweck, Ulrike; Berger, Luise Masami

    2010-01-01

    Context: Sportsmen’s groin, also called sports hernia and Gilmore groin, is one of the most frequent sports injuries in athletes and may place an athletic career at risk. It presents with acute or chronic groin pain exacerbated with physical activity. So far, there is little consensus regarding pathogenesis, diagnostic criteria, or treatment. There have been various attempts to explain the cause of the groin pain. The assumption is that a circumscribed weakness in the posterior wall of the inguinal canal, which leads to a localized bulge, induces a compression of the genital branch of the genitofemoral nerve, considered responsible for the symptoms. Methods: The authors developed an innovative open suture repair—the Minimal Repair technique—to fit the needs of professional athletes. With this technique, the circumscribed weakness of the posterior wall of the inguinal canal is repaired by an elastic suture; the compression on the nerve is abolished, and the cause of the pain is removed. In contrast with that of common open suture repairs, the defect of the posterior wall is not enlarged, the suture is nearly tension free, and the patient can return to full training and athletic activity within a shorter time. The outcome of patients undergoing operations with the Minimal Repair technique was compared with that of commonly used surgical procedures. Results: The following advantages of the Minimal Repair technique were found: no insertion of prosthetic mesh, no general anesthesia required, less traumatization, and lower risk of severe complications with equal or even faster convalescence. In 2009, a prospective cohort of 129 patients resumed training in 7 days and experienced complete pain relief in an average of 14 days. Professional athletes (67%) returned to full activity in 14 days (median). Conclusion: The Minimal Repair technique is an effective and safe way to treat sportsmen’s groin. PMID:23015941

  7. Development and applications of laser spectroscopic techniques related to combustion diagnostics

    International Nuclear Information System (INIS)

    Alden, Marcus

    2006-01-01

    Thanks to features as non-intrusiveness combined with high spatial and temporal resolution, various laser diagnostic techniques have during the last decades become of utmost importance for characterization of combustion related phenomena. In the following presentation some further development of the techniques will be highlighted aiming at a) surface temperatures using Thermographic Phosphors, TP, b) species specific, spatially and temporally resolved detection of species absorbing in the IR spectral region using polarization spectroscopy and Laser-induced fluorescence, and finally c) high speed visualization using a special designed laser system in combination with a framing camera. In terms of surface thermometry, Thermographic Phosphors have been used for many years for temperature measurements on solid surfaces. We have during the last years further developed and applied this technique for temperature measurements on burning surfaces and on materials going through phase shifts, e.g. pyrolysis and droplets. The basic principle behind this technique is to apply micron size particles to the surface of interest. By exciting the TP with a short pulse UV laser (ns), the phosphorescence will exhibit a behaviour where the spectral emission as well as the temporal decay are dependent on the temperature. It is thus possible to measure the temperature both in one and two dimensions. The presentation will include basic description of the technique as well as various applications, e.g in fire science, IC engines and gasturbines. Several of the species of interest for combustion/flow diagnostics exhibit a molecular structure which inhibits the use of conventional laser-induced fluorescence for spatially and spectrally resolved measurements. We have during the last years investigated the use of excitation and detection in the infrared region of the spectrum. Here, it is possible to detect both carbonmono/dioxide, water as well as species specific hydrocarbons. The techniques

  8. Effects of Different Compression Techniques on Diagnostic Accuracies of Breast Masses on Digitized Mammograms

    International Nuclear Information System (INIS)

    Zhigang Liang; Xiangying Du; Jiabin Liu; Yanhui Yang; Dongdong Rong; Xinyu Y ao; Kuncheng Li

    2008-01-01

    Background: The JPEG 2000 compression technique has recently been introduced into the medical imaging field. It is critical to understand the effects of this technique on the detection of breast masses on digitized images by human observers. Purpose: To evaluate whether lossless and lossy techniques affect the diagnostic results of malignant and benign breast masses on digitized mammograms. Material and Methods: A total of 90 screen-film mammograms including craniocaudal and lateral views obtained from 45 patients were selected by two non-observing radiologists. Of these, 22 cases were benign lesions and 23 cases were malignant. The mammographic films were digitized by a laser film digitizer, and compressed to three levels (lossless and lossy 20:1 and 40:1) using the JPEG 2000 wavelet-based image compression algorithm. Four radiologists with 10-12 years' experience in mammography interpreted the original and compressed images. The time interval was 3 weeks for each reading session. A five-point malignancy scale was used, with a score of 1 corresponding to definitely not a malignant mass, a score of 2 referring to not a malignant mass, a score of 3 meaning possibly a malignant mass, a score of 4 being probably a malignant mass, and a score of 5 interpreted as definitely a malignant mass. The radiologists' performance was evaluated using receiver operating characteristic analysis. Results: The average Az values for all radiologists decreased from 0.8933 for the original uncompressed images to 0.8299 for the images compressed at 40:1. This difference was not statistically significant. The detection accuracy of the original images was better than that of the compressed images, and the Az values decreased with increasing compression ratio. Conclusion: Digitized mammograms compressed at 40:1 could be used to substitute original images in the diagnosis of breast cancer

  9. The role of choline (Cho) in the diagnostics and differentiation of brain tumours with HMRS technique

    International Nuclear Information System (INIS)

    Sobiecka, B.; Urbanik, A.

    2009-01-01

    Background: The aim of the research was a comprehensive analysis of Cho concentration and Cho/Cr, NAA/Cho, NAA/Cho+Cr ratios for the purposes of the diagnostics and differentiation of brain tumours (the type of the pathological lesion in patients with brain tumours) with the use of HMRS technique. Material/Methods: The HMRS examinations were performed with the use of the MRI Signa Excite 1.5 T system, in PRESS technique (TR = 1500 ms, TE = 35 ms) and involved 100 patients with brain tumours (age range: 18 to 81 yrs, mean age 50.61). Spectra were taken from three different locations: tumour centre, the tumour edge and contralateral unchanged cerebral tissue. All patients underwent surgery followed by histopathological analysis, on the basis of which two groups were separated (benign tumours, malignant tumours - 50 cases each). Additionally, 30 healthy volunteers in the age of 20 to 79 years (mean age 40.8) were examined. Results: The comparison of the examined patients with the control group revealed significantly higher Cho concentrations in patients with brain tumours. The analysis of Cho concentration was also performed with consideration of the age factor (under and over 60 years of age). Significantly lower mean Cho concentrations were discovered in a group of patients under 60 years of age. The analysis of Cho concentrations and Cho/Cr ratios reveled statistical significance for two factors: voxel location factor and the type of the pathological lesion. The average of Cho concentration and Cho/Cr ratios were higher in the group of patients with malignant tumours. The highest Cho concentrations and Cho/Cr ratios were observed in the tumour centre. The relative NAA/Cho and NAA/Cho+Cr ratios were statistically significant when taking into consideration the voxel location factor only. The results received from contralateral normal cerebral tissue (the internal model) were compared with control group (the external model). Mean values of Cho concentration were

  10. Epidemiology of intestinal parasitosis in Italy between 2005 and 2008: diagnostic techniques and methodologies

    Directory of Open Access Journals (Sweden)

    Daniele Crotti

    2013-04-01

    Full Text Available Aim of the study was to keep a real and actual photo relating to 2005-2008 regarding to diagnostic techniques and methodologies for intestinal parasites; so it would be possible to know specific epidemiology and suggest more rational and efficacious guide-lines. All members of AMCLI were involved in the proposal of a retrospective study regarding bowel parasites, helminths and protozoa.To engaged laboratories we asked how O&P was performed, if a specifical research for E. vermicularis and S. stercoralis was performed, if for the identification of D. fragilis, Entamoeba histolytica/dispar and Cryptosporidum spp were performed recommended specific permanent stains. 23 laboratories gave assent; but for an inferior number was possible to use the data for analysis and evaluation. Relating O&P only some laboratories performed permanent stains: Giemsa for D. fragilis, antigen and/or Trichrome stain for E. histolytica/dispar, antigen and/or acid fast stain for Cryptosporidium spp.Not all laboratories research specifically S. stercoralis. So the epidemiology is differentiated and related more to adequate or not adequate techniques than cohorts of examined populations. The overall positivity for parasites ranged from 0% to18.7%,for protozoa (pathogens or not were from 0% to 14.7%; for nematodes from 0% to 3.7%; for cestodes from 0% to 1.0%; for trematodes from 0% to 1.0%.Among helminths, E. vermicularis, followed by S. stercoralis, also in O&P, is the most frequent.The specific research of S. stercoralis gave a positivity from 0% to 33.3%; the cellophane tape test was positive for E. vermicularis from 0% fo 21.9% of cases.Among pathogen protozoa, D. fragilis, when permanent stain were applied, prevailed from 0% to 16.6%; G. duodenalis from 0.8% to 4.3%; E. histolytica/dispar, using a permanent stain or research of antigen, was identified from 0% to 20.6%. Coccidia were very rare, with Cryptosporidium spp observed from 0% to 5.2%. These are our conclusions

  11. Mini-FLOTAC, an innovative direct diagnostic technique for intestinal parasitic infections: experience from the field.

    Science.gov (United States)

    Barda, Beatrice Divina; Rinaldi, Laura; Ianniello, Davide; Zepherine, Henry; Salvo, Fulvio; Sadutshang, Tsetan; Cringoli, Giuseppe; Clementi, Massimo; Albonico, Marco

    2013-01-01

    Soil-transmitted helminths and intestinal protozoa infection are widespread in developing countries, yet an accurate diagnosis is rarely performed. The aim of this study was to evaluate the recently developed mini-FLOTAC method and to compare with currently more widely used techniques for the diagnosis of intestinal parasitic infections in different settings. The study was carried out in Dharamsala, Himachal Pradesh, India, and in Bukumbi, Tanzania. A total of 180 pupils from two primary schools had their stool analyzed (n = 80 in Dharamsala and n = 100 in Bukumbi) for intestinal parasitic infections with three diagnostic methods: direct fecal smear, formol-ether concentration method (FECM) and mini-FLOTAC. Overall, 72% of the pupils were positive for any intestinal parasitic infection, 24% carried dual infections and 11% three infections or more. The most frequently encountered intestinal parasites were Entamoeba coli, Entamoeba histolytica/dispar, Giardia intestinalis, hookworm, (and Schistosoma mansoni, in Tanzania). Statistically significant differences were found in the detection of parasitic infections among the three methods: mini-FLOTAC was the most sensitive method for helminth infections (90% mini-FLOTAC, 60% FECM, and 30% direct fecal smear), whereas FECM was most sensitive for intestinal protozoa infections (88% FECM, 70% direct fecal smear, and 68% mini-FLOTAC). We present the first experiences with the mini-FLOTAC for the diagnosis of intestinal helminths and protozoa. Our results suggest that it is a valid, sensitive and potentially low-cost alternative technique that could be used in resource-limited settings--particularly for helminth diagnosis.

  12. Kinetic and Diagnostic Studies of Molecular Plasmas Using Laser Absorption Techniques

    International Nuclear Information System (INIS)

    Welzel, S; Rousseau, A; Davies, P B; Roepcke, J

    2007-01-01

    Within the last decade mid infrared absorption spectroscopy between 3 and 20 μm, known as Infrared Laser Absorption Spectroscopy (IRLAS) and based on tuneable semiconductor lasers, namely lead salt diode lasers, often called tuneable diode lasers (TDL), and quantum cascade lasers (QCL) has progressed considerably as a powerful diagnostic technique for in situ studies of the fundamental physics and chemistry of molecular plasmas. The increasing interest in processing plasmas containing hydrocarbons, fluorocarbons, organo-silicon and boron compounds has lead to further applications of IRLAS because most of these compounds and their decomposition products are infrared active. IRLAS provides a means of determining the absolute concentrations of the ground states of stable and transient molecular species, which is of particular importance for the investigation of reaction kinetics. Information about gas temperature and population densities can also be derived from IRLAS measurements. A variety of free radicals and molecular ions have been detected, especially using TDLs. Since plasmas with molecular feed gases are used in many applications such as thin film deposition, semiconductor processing, surface activation and cleaning, and materials and waste treatment, this has stimulated the adaptation of infrared spectroscopic techniques to industrial requirements. The recent development of QCLs offers an attractive new option for the monitoring and control of industrial plasma processes as well as for highly time-resolved studies on the kinetics of plasma processes. The aim of the present article is threefold: (i) to review recent achievements in our understanding of molecular phenomena in plasmas (ii) to report on selected studies of the spectroscopic properties and kinetic behaviour of radicals, and (iii) to describe the current status of advanced instrumentation for TDLAS in the mid infrared

  13. Diagnostic value of the fluoroscopic triggering 3D LAVA technique for primary liver cancer.

    Science.gov (United States)

    Shen, Xiao-Yong; Chai, Chun-Hua; Xiao, Wen-Bo; Wang, Qi-Dong

    2010-04-01

    Primary liver cancer (PLC) is one of the common malignant tumors. Liver acquisition with acceleration volume acquisition (LAVA), which allows simultaneous dynamic enhancement of the hepatic parenchyma and vasculature imaging, is of great help in the diagnosis of PLC. This study aimed to evaluate application of the fluoroscopic triggering 3D LAVA technique in the imaging of PLC and liver vasculature. The clinical data and imaging findings of 38 adults with PLC (22 men and 16 women; average age 52 years), pathologically confirmed by surgical resection or biopsy, were collected and analyzed. All magnetic resonance images were obtained with a 1.5-T system (General Electrics Medical Systems) with an eight-element body array coil and application of the fluoroscopic triggering 3D LAVA technique. Overall image quality was assessed on a 5-point scale by two experienced radiologists. All the nodules and blood vessel were recorded and compared. The diagnostic accuracy and feasibility of LAVA were evaluated. Thirty-eight patients gave high quality images of 72 nodules in the liver for diagnosis. The accuracy of LAVA was 97.2% (70/72), and the coincidence rate between the extent of tumor judged by dynamic enhancement and pathological examination was 87.5% (63/72). Displayed by the maximum intensity projection reconstruction, nearly all cases gave satisfactory images of branches III and IV of the hepatic artery. Furthermore, small early-stage enhancing hepatic lesions and the parallel portal vein were also well displayed. Sequence of LAVA provides good multi-phase dynamic enhancement scanning of hepatic lesions. Combined with conventional scanning technology, LAVA effectively and safely displays focal hepatic lesions and the relationship between tumor and normal tissues, especially blood vessels.

  14. Development of an Accident Diagnostic Scheme Using Artificial Intelligence Techniques (I)

    Energy Technology Data Exchange (ETDEWEB)

    Na, M. G.; Lee, S. H.; Kim, D. S.; No, Y. G.; Lee, S. W. [Chosun University, Gwangju (Korea, Republic of); Ahn, K. I. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2010-06-15

    As a means to effectively manage the severe nuclear accidents, it is important to identify and diagnose the accident initiating events during an initial short time interval after the accidents by observing the major controlling parameters. Main objective of this study is to develop the diagnostic approach for the accurate prediction of accident initiating events using artificial intelligence techniques. For this, first, a variety of artificial intelligence techniques such as Finn, Gmbh, and Sm were examined through this study. Among them, Sc and Gmbh model were assessed as a useful approach to predict the break location and the break size of Local. In order to verify the proposed algorithm, the 111 accident simulation data (based on Map) were applied to train the Sc and Gmbh models, and the test data was used to independently verify whether or not the SVC and GMDH models work well. The analysis of the maximum errors and RMS errors, and the performance of the GMDH according to the existence of measurement errors and SIS actuation showed that the proposed SVC and GMDH models can accurately classify the break locations and accurately predict the break size. As the time-integrated signals were used for inputs into the GMDH model within a period of 60 second after a reactor scram, the actuation of the safety systems such as safety injection system (SIS), auxiliary feed water system, and containment spray system, were not considered in this study. It is because the initial 60 second time-integrated signals were used and the safety systems usually start to actuate after a more than 60 second time delay after the reactor scram

  15. Development of an Accident Diagnostic Scheme Using Artificial Intelligence Techniques (I)

    International Nuclear Information System (INIS)

    Na, M. G.; Lee, S. H.; Kim, D. S.; No, Y. G.; Lee, S. W.; Ahn, K. I.

    2010-06-01

    As a means to effectively manage the severe nuclear accidents, it is important to identify and diagnose the accident initiating events during an initial short time interval after the accidents by observing the major controlling parameters. Main objective of this study is to develop the diagnostic approach for the accurate prediction of accident initiating events using artificial intelligence techniques. For this, first, a variety of artificial intelligence techniques such as Finn, Gmbh, and Sm were examined through this study. Among them, Sc and Gmbh model were assessed as a useful approach to predict the break location and the break size of Local. In order to verify the proposed algorithm, the 111 accident simulation data (based on Map) were applied to train the Sc and Gmbh models, and the test data was used to independently verify whether or not the SVC and GMDH models work well. The analysis of the maximum errors and RMS errors, and the performance of the GMDH according to the existence of measurement errors and SIS actuation showed that the proposed SVC and GMDH models can accurately classify the break locations and accurately predict the break size. As the time-integrated signals were used for inputs into the GMDH model within a period of 60 second after a reactor scram, the actuation of the safety systems such as safety injection system (SIS), auxiliary feed water system, and containment spray system, were not considered in this study. It is because the initial 60 second time-integrated signals were used and the safety systems usually start to actuate after a more than 60 second time delay after the reactor scram

  16. Comparative value of diagnostic imaging techniques in a cat with exophthalmos

    International Nuclear Information System (INIS)

    Ramsey, D.T.; Gerding, P.A. Jr.; Losonsky, J.M.; Kuriashkin, I.V.; Clarkson, R.D.

    1994-01-01

    A mass that appeared to originate from the frontal bone and extended into retrobulbar tissues of the light orbit was imaged in a cat using ultrasound, skull radiographs, computed tomography, and magnetic resonance imaging. The cat was presented with ventrolateral strabismus, exophthalmos, and elevated nictitans membrane of the tight eye. The mass was not delineated entirely after orbital echography and survey radiography of the skull was performed. Cytologic examination of fine-needle aspirate of the mass was suggestive of a neoplastic disease. Results of computed tomography indicated lysis of the calvarium but did not delineate borders of the mass in the calvarium. Magnetic resonance imaging was then used to confirm borders of the neoplasm. Magnetic resonance imaging was the only imaging technique that delineated the entire border of the neoplasm, including in the calvarium, when compared to postmortem evaluation. Results of orbital echography, skull radiographs, or computed tomography, when used as the only diagnostic imaging modality, must be interpreted with caution when evaluating borders of retrobulbar neoplasia prior to surgical planning

  17. Fungal disease detection in plants: Traditional assays, novel diagnostic techniques and biosensors.

    Science.gov (United States)

    Ray, Monalisa; Ray, Asit; Dash, Swagatika; Mishra, Abtar; Achary, K Gopinath; Nayak, Sanghamitra; Singh, Shikha

    2017-01-15

    Fungal diseases in commercially important plants results in a significant reduction in both quality and yield, often leading to the loss of an entire plant. In order to minimize the losses, it is essential to detect and identify the pathogens at an early stage. Early detection and accurate identification of pathogens can control the spread of infection. The present article provides a comprehensive overview of conventional methods, current trends and advances in fungal pathogen detection with an emphasis on biosensors. Traditional techniques are the "gold standard" in fungal detection which relies on symptoms, culture-based, morphological observation and biochemical identifications. In recent times, with the advancement of biotechnology, molecular and immunological approaches have revolutionized fungal disease detection. But the drawback lies in the fact that these methods require specific and expensive equipments. Thus, there is an urgent need for rapid, reliable, sensitive, cost effective and easy to use diagnostic methods for fungal pathogen detection. Biosensors would become a promising and attractive alternative, but they still have to be subjected to some modifications, improvements and proper validation for on-field use. Copyright © 2016 Elsevier B.V. All rights reserved.

  18. Nonculture molecular techniques for diagnosis of bacterial disease in animals: a diagnostic laboratory perspective.

    Science.gov (United States)

    Cai, H Y; Caswell, J L; Prescott, J F

    2014-03-01

    The past decade has seen remarkable technical advances in infectious disease diagnosis, and the pace of innovation is likely to continue. Many of these techniques are well suited to pathogen identification directly from pathologic or clinical samples, which is the focus of this review. Polymerase chain reaction (PCR) and gene sequencing are now routinely performed on frozen or fixed tissues for diagnosis of bacterial infections of animals. These assays are most useful for pathogens that are difficult to culture or identify phenotypically, when propagation poses a biosafety hazard, or when suitable fresh tissue is not available. Multiplex PCR assays, DNA microarrays, in situ hybridization, massive parallel DNA sequencing, microbiome profiling, molecular typing of pathogens, identification of antimicrobial resistance genes, and mass spectrometry are additional emerging technologies for the diagnosis of bacterial infections from pathologic and clinical samples in animals. These technical advances come, however, with 2 caveats. First, in the age of molecular diagnosis, quality control has become more important than ever to identify and control for the presence of inhibitors, cross-contamination, inadequate templates from diagnostic specimens, and other causes of erroneous microbial identifications. Second, the attraction of these technologic advances can obscure the reality that medical diagnoses cannot be made on the basis of molecular testing alone but instead through integrated consideration of clinical, pathologic, and laboratory findings. Proper validation of the method is required. It is critical that veterinary diagnosticians understand not only the value but also the limitations of these technical advances for routine diagnosis of infectious disease.

  19. Spiral CT during pharmacoangiography with angiotensin II in patients with pancreatic disease. Technique and diagnostic efficacy

    Energy Technology Data Exchange (ETDEWEB)

    Kuroda, C.; Mihara, N.; Hosomi, N.; Inoue, E.; Fujita, M. [Osaka Medical Center for Cancer and Cardiovascular Diseases (Japan). Dept. of Diagnostic Radiology; Ohigashi, H.; Ishikawa, O. [Osaka Medical Center for Cancer and Cardiovascular Diseases (Japan). Dept. of Surgery; Nakaizumi, A. [Osaka Medical Center for Cancer and Cardiovascular Deseases (Japan). Dept. of Internal Medicine; Ishiguro, S. [Osaka Medical Center for Cancer and Cardiovascular Diseases (Japan). Dept. of Pathology

    1998-03-01

    Purpose: To compare the diagnostic efficacy of pancreatic pharmacoangiographic CT using angiotensin II with conventional angiographic CT. Material and Methods: Eighteen patients with space-occupying pancreatic disease were examined in this study. Pharmacoangiographic CT was performed with a 1-3-{mu}/6-ml solution of angiotensin II injected through a catheter into the celiac artery during spiral CT. Results: In 17 of the 18 (94%) patients, the area of pancreatic parenchymal enhancement was the same or larger at pharmacoangiographic CT than at conventional angiographic CT. The attenuation value of the pancreatic parenchyma was significantly increased at pharmacoangiographic CT (p=0.0010). Although the attenuation value of tumors was also increased on images obtained after the injection of angiotensin II, the tumor-to-pancreas contrast was significantly greater at pharmacoangiographic CT (p=0.0479). The mean differences in attenuation between tumor and pancreas at angiographic CT with and without angiotensin II were respectively 182 HU and 115 HU. Conclusion: Pharmacoangiographic CT with angiotensin II proved superior to conventional angiographic CT in the diagnosis of pancreatic disease. We therefore recommend it as a supplementary technique at the angiographic examination of patients with suspected pancreatic tumor. (orig.).

  20. Modern Diagnostic Techniques for the Assessment of Ocular Blood Flow in Myopia: Current State of Knowledge.

    Science.gov (United States)

    Grudzińska, Ewa; Modrzejewska, Monika

    2018-01-01

    Myopia is the most common refractive error and the subject of interest of various studies assessing ocular blood flow. Increasing refractive error and axial elongation of the eye result in the stretching and thinning of the scleral, choroid, and retinal tissues and the decrease in retinal vessel diameter, disturbing ocular blood flow. Local and systemic factors known to change ocular blood flow include glaucoma, medications and fluctuations in intraocular pressure, and metabolic parameters. Techniques and tools assessing ocular blood flow include, among others, laser Doppler flowmetry (LDF), retinal function imager (RFI), laser speckle contrast imaging (LSCI), magnetic resonance imaging (MRI), optical coherence tomography angiography (OCTA), pulsatile ocular blood flowmeter (POBF), fundus pulsation amplitude (FPA), colour Doppler imaging (CDI), and Doppler optical coherence tomography (DOCT). Many researchers consistently reported lower blood flow parameters in myopic eyes regardless of the used diagnostic method. It is unclear whether this is a primary change that causes secondary thinning of ocular tissues or quite the opposite; that is, the mechanical stretching of the eye wall reduces its thickness and causes a secondary lower demand of tissues for oxygen. This paper presents a review of studies assessing ocular blood flow in myopes.

  1. Practical X-ray diagnostics orthopedics and trauma surgery. Indication, adjustment technique and radiation protection

    International Nuclear Information System (INIS)

    Flechtenmacher, Johannes; Sabo, Desiderius

    2014-01-01

    The book on X-ray diagnostics in orthopedics and trauma surgery includes the following chapters: 1. Introduction: radiation protection, equipment technology radiological diagnostics of skeleton carcinomas, specific aspects of trauma surgery, special aspects of skeleton radiology for children. 2. X-ray diagnostics of different anatomical regions: ankle joint, knee, hips and pelvis, hand and wrist joint, elbow, shoulder, spinal cord. 3. Appendix: radiation protection according to the X-ray regulations.

  2. A comparison of analogue and digital techniques in upper gastrointestinal examinations: absorbed dose and diagnostic quality of the images

    Energy Technology Data Exchange (ETDEWEB)

    Axelsson, B.; Hansson, I.B. [Department of Hospital Physics, Karolinska Hospital, Stockholm (Sweden); Boden, K.; Witt, H.H. [Department of Diagnostic Radiology, Karolinska Hospital, Stockholm (Sweden); Fransson, S.G. [Department of Thoracic Radiology, University Hospital, Linkoeping (Sweden); Persliden, J. [Department of Radiation Physics, University Hospital, Linkoeping (Sweden)

    2000-08-01

    This study was performed to investigate whether patient exposure and diagnostic quality of the image is significantly influenced by the introduction of digital image acquisition techniques. Evaluation was performed for three different techniques (analogue, analogue fluoro+digital radiography, digital) in examination of the upper gastrointestinal tract. The evaluation was done from data acquired in three different departments. Patient exposure was recorded as KERMA-area product (KAP) and the individual patient readings were normalised to a standard size patient. Image quality was assessed using visual grading with a reference image. The recorded KAP values were significantly higher (22.3 Gycm{sup 2}) for the fully digital technique compared to the others (analogue 6.8 Gycm{sup 2}, analogue+digital 3.6 Gycm{sup 2}). This was due mostly to an increased number of exposures. The diagnostic quality of the image was, however, also regarded to be slightly lower for the technique giving the lowest patient dose with the smallest number of exposures (analogue+digital). The digital examination technique, as used in this study, thus resulted in significantly higher patient dose without any significant gain in diagnostic quality of the image. (orig.)

  3. A comparison of analogue and digital techniques in upper gastrointestinal examinations: absorbed dose and diagnostic quality of the images

    International Nuclear Information System (INIS)

    Axelsson, B.; Hansson, I.B.; Boden, K.; Witt, H.H.; Fransson, S.G.; Persliden, J.

    2000-01-01

    This study was performed to investigate whether patient exposure and diagnostic quality of the image is significantly influenced by the introduction of digital image acquisition techniques. Evaluation was performed for three different techniques (analogue, analogue fluoro+digital radiography, digital) in examination of the upper gastrointestinal tract. The evaluation was done from data acquired in three different departments. Patient exposure was recorded as KERMA-area product (KAP) and the individual patient readings were normalised to a standard size patient. Image quality was assessed using visual grading with a reference image. The recorded KAP values were significantly higher (22.3 Gycm 2 ) for the fully digital technique compared to the others (analogue 6.8 Gycm 2 , analogue+digital 3.6 Gycm 2 ). This was due mostly to an increased number of exposures. The diagnostic quality of the image was, however, also regarded to be slightly lower for the technique giving the lowest patient dose with the smallest number of exposures (analogue+digital). The digital examination technique, as used in this study, thus resulted in significantly higher patient dose without any significant gain in diagnostic quality of the image. (orig.)

  4. Use of sting-response techniques for simulate diagnostics in human esophagus

    International Nuclear Information System (INIS)

    Rodriguez, I.; Gonzalez, Y.; Valdes, L.; Alfonso, J.A.; Estevez, E.

    2003-01-01

    In this work a study of simulation of the gamma graphic studies that are carried out in human esophagus in the Dept. of Nuclear Medicine of the 'Celestino Hernandez Robau Hospital of Santa Clara is presented. For the investigation tubular reactors were used and sting-response techniques with radioactive tracer of Technetium 99 metastable to a concentration of 1 mCi and several flows were applied. The distribution curves of residences times were obtained, those that respond to an equation of the type: Y = A + B exp (- exp((x-C)/D)) - ((x-C/D)+1). They were also carried out, optimizations studies of the doses of the radioactive to give to the patients from 1 mCi (that is the one used in studies) up to 0,5 mCi, and the influences on the obtained distributions of residence time were analyzed. It was confirmed the possibility to lower the doses with clear information of the signal. It was also carried out a simulation of the attenuation of the radiations that takes place in the patients by the interposition of tissues among the analyzed organ, and the detection equipment. It was used paraffin for tissue simulation. It was found the almost independence of the intensity of the radiations with the thickness, for the assayed doses. Lastly it was found a complex mathematical model that responds to the diagnostic curves obtained in these studies, being correlated the coefficients of the pattern with the most important physical parameters of the system, giving it a practical and useful value, all time that the error among the values that this it predicts and the experimental ones do not surpass of 5%. (Author)

  5. Breast Cancer-Related Arm Lymphedema: Incidence Rates, Diagnostic Techniques, Optimal Management and Risk Reduction Strategies

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Chirag [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States); Vicini, Frank A., E-mail: fvicini@beaumont.edu [Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI (United States)

    2011-11-15

    As more women survive breast cancer, long-term toxicities affecting their quality of life, such as lymphedema (LE) of the arm, gain importance. Although numerous studies have attempted to determine incidence rates, identify optimal diagnostic tests, enumerate efficacious treatment strategies and outline risk reduction guidelines for breast cancer-related lymphedema (BCRL), few groups have consistently agreed on any of these issues. As a result, standardized recommendations are still lacking. This review will summarize the latest data addressing all of these concerns in order to provide patients and health care providers with optimal, contemporary recommendations. Published incidence rates for BCRL vary substantially with a range of 2-65% based on surgical technique, axillary sampling method, radiation therapy fields treated, and the use of chemotherapy. Newer clinical assessment tools can potentially identify BCRL in patients with subclinical disease with prospective data suggesting that early diagnosis and management with noninvasive therapy can lead to excellent outcomes. Multiple therapies exist with treatments defined by the severity of BCRL present. Currently, the standard of care for BCRL in patients with significant LE is complex decongestive physiotherapy (CDP). Contemporary data also suggest that a multidisciplinary approach to the management of BCRL should begin prior to definitive treatment for breast cancer employing patient-specific surgical, radiation therapy, and chemotherapy paradigms that limit risks. Further, prospective clinical assessments before and after treatment should be employed to diagnose subclinical disease. In those patients who require aggressive locoregional management, prophylactic therapies and the use of CDP can help reduce the long-term sequelae of BCRL.

  6. Breast Cancer-Related Arm Lymphedema: Incidence Rates, Diagnostic Techniques, Optimal Management and Risk Reduction Strategies

    International Nuclear Information System (INIS)

    Shah, Chirag; Vicini, Frank A.

    2011-01-01

    As more women survive breast cancer, long-term toxicities affecting their quality of life, such as lymphedema (LE) of the arm, gain importance. Although numerous studies have attempted to determine incidence rates, identify optimal diagnostic tests, enumerate efficacious treatment strategies and outline risk reduction guidelines for breast cancer–related lymphedema (BCRL), few groups have consistently agreed on any of these issues. As a result, standardized recommendations are still lacking. This review will summarize the latest data addressing all of these concerns in order to provide patients and health care providers with optimal, contemporary recommendations. Published incidence rates for BCRL vary substantially with a range of 2–65% based on surgical technique, axillary sampling method, radiation therapy fields treated, and the use of chemotherapy. Newer clinical assessment tools can potentially identify BCRL in patients with subclinical disease with prospective data suggesting that early diagnosis and management with noninvasive therapy can lead to excellent outcomes. Multiple therapies exist with treatments defined by the severity of BCRL present. Currently, the standard of care for BCRL in patients with significant LE is complex decongestive physiotherapy (CDP). Contemporary data also suggest that a multidisciplinary approach to the management of BCRL should begin prior to definitive treatment for breast cancer employing patient-specific surgical, radiation therapy, and chemotherapy paradigms that limit risks. Further, prospective clinical assessments before and after treatment should be employed to diagnose subclinical disease. In those patients who require aggressive locoregional management, prophylactic therapies and the use of CDP can help reduce the long-term sequelae of BCRL.

  7. Uncertainty Management for Diagnostics and Prognostics of Batteries using Bayesian Techniques

    Data.gov (United States)

    National Aeronautics and Space Administration — Uncertainty management has always been the key hurdle faced by diagnostics and prognostics algorithms. A Bayesian treatment of this problem provides an elegant and...

  8. Advanced Surveillance, Diagnostic and Prognostic Techniques in Monitoring Structures, Systems and Components in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-09-15

    direction of research, development and demonstration in this area. The technologies discussed in this project are intended to establish the state of the art in surveillance, diagnostics and prognostics (SDP) technologies for equipment and process health monitoring in nuclear facilities. It is also intended to identify technology gaps and research needs of the nuclear industry in the area of SDP. The report draws on the conventional SDP technologies, as well as the latest tools, algorithms and techniques that have emerged over the last few years, especially in enabling technologies including fast data acquisition, data storage, data qualification and data analysis algorithms, such as empirical and physical modelling techniques. These new tools have made it possible to identify problems earlier and with better resolution. The significance of the material presented in this report is that it contributes not only to the current needs of the nuclear industry but also to the design improvements of the next generation of reactors. For example, the nuclear industry is currently striving to operate the plants for up to 80 years or more, as the value of nuclear assets has risen in recent years, resulting partly from environmental concerns with fossil energy production, as well as increased future demand for base load electricity. This long term operation (LTO) or life extension goal of the nuclear industry has stimulated renewed interest in more frequent monitoring of equipment to guard against ageing effects, not to mention the economic benefits that SDP implementation can produce, and contributions to radiation exposure that is as low as reasonably achievable, reduction of human errors, and optimized maintenance. Together with capabilities that enhance situational awareness, the technologies described in this report will enable more holistic management of plant structures, systems and components (SSCs), maintain high capacity factor in LTO and enable higher levels of safe operation

  9. Advanced Surveillance, Diagnostic and Prognostic Techniques in Monitoring Structures, Systems and Components in Nuclear Power Plants

    International Nuclear Information System (INIS)

    2013-01-01

    direction of research, development and demonstration in this area. The technologies discussed in this project are intended to establish the state of the art in surveillance, diagnostics and prognostics (SDP) technologies for equipment and process health monitoring in nuclear facilities. It is also intended to identify technology gaps and research needs of the nuclear industry in the area of SDP. The report draws on the conventional SDP technologies, as well as the latest tools, algorithms and techniques that have emerged over the last few years, especially in enabling technologies including fast data acquisition, data storage, data qualification and data analysis algorithms, such as empirical and physical modelling techniques. These new tools have made it possible to identify problems earlier and with better resolution. The significance of the material presented in this report is that it contributes not only to the current needs of the nuclear industry but also to the design improvements of the next generation of reactors. For example, the nuclear industry is currently striving to operate the plants for up to 80 years or more, as the value of nuclear assets has risen in recent years, resulting partly from environmental concerns with fossil energy production, as well as increased future demand for base load electricity. This long term operation (LTO) or life extension goal of the nuclear industry has stimulated renewed interest in more frequent monitoring of equipment to guard against ageing effects, not to mention the economic benefits that SDP implementation can produce, and contributions to radiation exposure that is as low as reasonably achievable, reduction of human errors, and optimized maintenance. Together with capabilities that enhance situational awareness, the technologies described in this report will enable more holistic management of plant structures, systems and components (SSCs), maintain high capacity factor in LTO and enable higher levels of safe operation

  10. Development of a diagnostic technique based on Cherenkov effect for measurements of fast electrons in fusion devices

    Energy Technology Data Exchange (ETDEWEB)

    Plyusnin, V. V.; Duarte, P.; Fernandes, H.; Silva, C. [Association Euratom/IST, Instituto de Plasmas e Fusao Nuclear, Instituto Superior Tecnico, Universidade Tecnica de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa (Portugal); Jakubowski, L.; Zebrowski, J.; Malinowski, K.; Rabinski, M.; Sadowski, M. J. [National Centre for Nuclear Research (NCBJ), 7 Andrzeja Soltana Str., 05-400 Otwock (Poland)

    2012-08-15

    A diagnostic technique based on the Cherenkov effect is proposed for detection and characterization of fast (super-thermal and runaway) electrons in fusion devices. The detectors of Cherenkov radiation have been specially designed for measurements in the ISTTOK tokamak. Properties of several materials have been studied to determine the most appropriate one to be used as a radiator of Cherenkov emission in the detector. This technique has enabled the detection of energetic electrons (70 keV and higher) and the determination of their spatial and temporal variations in the ISTTOK discharges. Measurement of hard x-ray emission has also been carried out in experiments for validation of the measuring capabilities of the Cherenkov-type detector and a high correlation was found between the data of both diagnostics. A reasonable agreement was found between experimental data and the results of numerical modeling of the runaway electron generation in ISTTOK.

  11. Diagnostic tools for nearest neighbors techniques when used with satellite imagery

    Science.gov (United States)

    Ronald E. McRoberts

    2009-01-01

    Nearest neighbors techniques are non-parametric approaches to multivariate prediction that are useful for predicting both continuous and categorical forest attribute variables. Although some assumptions underlying nearest neighbor techniques are common to other prediction techniques such as regression, other assumptions are unique to nearest neighbor techniques....

  12. The Diagnostic Challenge Competition: Probabilistic Techniques for Fault Diagnosis in Electrical Power Systems

    Science.gov (United States)

    Ricks, Brian W.; Mengshoel, Ole J.

    2009-01-01

    Reliable systems health management is an important research area of NASA. A health management system that can accurately and quickly diagnose faults in various on-board systems of a vehicle will play a key role in the success of current and future NASA missions. We introduce in this paper the ProDiagnose algorithm, a diagnostic algorithm that uses a probabilistic approach, accomplished with Bayesian Network models compiled to Arithmetic Circuits, to diagnose these systems. We describe the ProDiagnose algorithm, how it works, and the probabilistic models involved. We show by experimentation on two Electrical Power Systems based on the ADAPT testbed, used in the Diagnostic Challenge Competition (DX 09), that ProDiagnose can produce results with over 96% accuracy and less than 1 second mean diagnostic time.

  13. Development of a neural network technique for KSTAR Thomson scattering diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seung Hun, E-mail: leesh81@nfri.re.kr; Lee, J. H. [National Fusion Research Institute, 169-148 Gwahak-ro, Yuseong-gu, Daejeon 34133 (Korea, Republic of); Yamada, I. [National Institute Fusion Science, Toki, Gifu 509-5292 (Japan); Park, Jae Sun [Department of Physics, Korea Advanced Institute of Science and Technology, 291 Daehak-ro, Yuseong-gu, Daejeon 34141 (Korea, Republic of)

    2016-11-15

    Neural networks provide powerful approaches of dealing with nonlinear data and have been successfully applied to fusion plasma diagnostics and control systems. Controlling tokamak plasmas in real time is essential to measure the plasma parameters in situ. However, the χ{sup 2} method traditionally used in Thomson scattering diagnostics hampers real-time measurement due to the complexity of the calculations involved. In this study, we applied a neural network approach to Thomson scattering diagnostics in order to calculate the electron temperature, comparing the results to those obtained with the χ{sup 2} method. The best results were obtained for 10{sup 3} training cycles and eight nodes in the hidden layer. Our neural network approach shows good agreement with the χ{sup 2} method and performs the calculation twenty times faster.

  14. Diagnostics of glass fiber reinforced polymers and comparative analysis of their fabrication techniques with the use of acoustic emission

    Science.gov (United States)

    Bashkov, O. V.; Bryansky, A. A.; Panin, S. V.; Zaikov, V. I.

    2016-11-01

    Strength properties of the glass fiber reinforced polymers (GFRP) fabricated by vacuum and vacuum autoclave molding techniques were analyzed. Measurements of porosity of the GFRP parts manufactured by various molding techniques were conducted with the help of optical microscopy. On the basis of experimental data obtained by means of acoustic emission hardware/software setup, the technique for running diagnostics and forecasting the bearing capacity of polymeric composite materials based on the result of three-point bending tests has been developed. The operation principle of the technique is underlined by the evaluation of the power function index change which takes place on the dependence of the total acoustic emission counts versus the loading stress.

  15. Estimating the burden of pneumococcal pneumonia among adults: a systematic review and meta-analysis of diagnostic techniques.

    Directory of Open Access Journals (Sweden)

    Maria A Said

    Full Text Available Pneumococcal pneumonia causes significant morbidity and mortality among adults. Given limitations of diagnostic tests for non-bacteremic pneumococcal pneumonia, most studies report the incidence of bacteremic or invasive pneumococcal disease (IPD, and thus, grossly underestimate the pneumococcal pneumonia burden. We aimed to develop a conceptual and quantitative strategy to estimate the non-bacteremic disease burden among adults with community-acquired pneumonia (CAP using systematic study methods and the availability of a urine antigen assay.We performed a systematic literature review of studies providing information on the relative yield of various diagnostic assays (BinaxNOW® S. pneumoniae urine antigen test (UAT with blood and/or sputum culture in diagnosing pneumococcal pneumonia. We estimated the proportion of pneumococcal pneumonia that is bacteremic, the proportion of CAP attributable to pneumococcus, and the additional contribution of the Binax UAT beyond conventional diagnostic techniques, using random effects meta-analytic methods and bootstrapping. We included 35 studies in the analysis, predominantly from developed countries. The estimated proportion of pneumococcal pneumonia that is bacteremic was 24.8% (95% CI: 21.3%, 28.9%. The estimated proportion of CAP attributable to pneumococcus was 27.3% (95% CI: 23.9%, 31.1%. The Binax UAT diagnosed an additional 11.4% (95% CI: 9.6, 13.6% of CAP beyond conventional techniques. We were limited by the fact that not all patients underwent all diagnostic tests and by the sensitivity and specificity of the diagnostic tests themselves. We address these resulting biases and provide a range of plausible values in order to estimate the burden of pneumococcal pneumonia among adults.Estimating the adult burden of pneumococcal disease from bacteremic pneumococcal pneumonia data alone significantly underestimates the true burden of disease in adults. For every case of bacteremic pneumococcal pneumonia

  16. Intercomparison of techniques for inspection and diagnostics of heavy water reactor pressure tubes. Determination of hydrogen concentration and blister characterization

    International Nuclear Information System (INIS)

    2009-03-01

    Heavy water reactors (HWRs) comprise significant numbers of today's operating nuclear power plants, and more are under construction. Efficient and accurate inspection and diagnostic techniques for various reactor components and systems, especially pressure tubes, are an important factor in ensuring reliable and safe plant operation. To foster international collaboration in the efficient and safe use of nuclear power, the IAEA conducted a Coordinated Research Project (CRP) on Intercomparison of Techniques for HWR Pressure Tube Inspection and Diagnostics. This CRP was carried out within the framework of the IAEA's Technical Working Group on Advanced Technologies for HWRs (the TWG-HWR). The TWG-HWR is a group of experts nominated by their governments and designated by the IAEA to provide advice and to support implementation of IAEA's project on advanced technologies for HWRs. The objective of the CRP was to compare non-destructive inspection and diagnostic techniques, in use and being developed, for structural integrity assessment of HWR pressure tubes. During the first phase of this CRP participants investigated the capability of different techniques to detect and characterize flaws. During the second phase participants collaborated to detect and characterize hydride blisters and to determine the hydrogen concentration in zirconium alloys. The intention was to identify the most effective pressure tube inspection and diagnostic methods and to identify further development needs. The organizations which participated in phase 2 of this CRP are: - Comision Nacional de Energia Atomica (CNEA), Argentina; - Atomic Energy of Canada Ltd. (AECL), Chalk River Laboratories (CRL), Canada; - Bhabha Atomic Research Centre (BARC), India; - Korea Atomic Energy Research Institute (KAERI), Republic of Korea; - National Institute for Research and Development for Technical Physics (NIRDTP), Romania; - Nuclear Non-Destructive Testing Research and Services (NNDT), Romania. IAEA-TECDOC-1499

  17. Principles for new optical techniques in medical diagnostics for mHealth applications

    Science.gov (United States)

    Balsam, Joshua Michael

    Medical diagnostics is a critical element of effective medical treatment. However, many modern and emerging diagnostic technologies are not affordable or compatible with the needs and conditions found in low-income and middle-income countries and regions. Resource-poor areas require low-cost, robust, easy-to-use, and portable diagnostics devices compatible with telemedicine (i.e. mHealth) that can be adapted to meet diverse medical needs. Many suitable devices will need to be based on optical technologies, which are used for many types of biological analyses. This dissertation describes the fabrication and detection principles for several low-cost optical technologies for mHealth applications including: (1) a webcam based multi-wavelength fluorescence plate reader, (2) a lens-free optical detector used for the detection of Botulinum A neurotoxin activity, (3) a low cost micro-array reader that allows the performance of typical fluorescence based assays demonstrated for the detection of the toxin staphylococcal enterotoxin (SEB), and (4) a wide-field flow cytometer for high throughput detection of fluorescently labeled rare cells. This dissertation discusses how these technologies can be harnessed using readily available consumer electronics components such as webcams, cell phones, CCD cameras, LEDs, and laser diodes. There are challenges in developing devices with sufficient sensitivity and specificity, and approaches are presented to overcoming these challenges to create optical detectors that can serve as low cost medical diagnostics in resource-poor settings for mHealth.

  18. Development of in situ cleaning techniques for diagnostic mirrors in ITER

    International Nuclear Information System (INIS)

    Litnovsky, A.; Laengner, M.; Matveeva, M.; Schulz, Ch.; Marot, L.; Voitsenya, V.S.; Philipps, V.; Biel, W.; Samm, U.

    2011-01-01

    Mirrors will be used in all optical and laser-based diagnostic systems of ITER. In the severe environment, the optical characteristics of mirrors will be degraded, hampering the entire performance of the respective diagnostics. A minute impurity deposition of 20 nm of carbon on the mirror is sufficient to decrease the mirror reflectivity by tens of percent outlining the necessity of the mirror cleaning in ITER. The results of R and D on plasma cleaning of molybdenum diagnostic mirrors are reported. The mirrors contaminated with amorphous carbon films in the laboratory conditions and in the tokamaks were cleaned in steady-state hydrogenic plasmas. The maximum cleaning efficiency of 4.2 nm/min was reached for the laboratory and soft tokamak hydrocarbon films, whereas for the hard tokamak films the carbidization of mirrors drastically decreased the cleaning efficiency down to 0.016 nm/min. This implies the necessity of sputtering cleaning of contaminated mirrors as the only reliable tool to remove the deposits by plasma cleaning. An overview of R and D program on mirror cleaning is provided along with plans for further studies and the recommendations for ITER mirror-based diagnostics.

  19. Draft of diagnostic techniques for primary coolant circuit facilities using control computer

    International Nuclear Information System (INIS)

    Suchy, R.; Procka, V.; Murin, V.; Rybarova, D.

    A method is proposed of in-service on-line diagnostics of primary circuit selected parts by means of a control computer. Computer processing will involve the measurements of neutron flux, pressure difference in pumps and in the core, and the vibrations of primary circuit mechanical parts. (H.S.)

  20. THE TECHNIQUE OF DIAGNOSTICS OF THE PRODUCTION CAPACITY OF THE ORGANIZATION

    Directory of Open Access Journals (Sweden)

    E. S. Popova

    2014-01-01

    Full Text Available In the article due to the need for diagnostics of the production capacity of the organization. Formed methodological framework for evaluating the production potential of the organization. Research capacity will also enable the organization to timely respond to current changes. A classification of types of diagnostics of the production capacity of the organization according to the following criteria: timing, goals, content, purpose results. The article discusses the economic and organizational diagnosis of the production capacity of the organization. Economic diagnosis is based on the calculation of indicators of use of resources of the organization. Organizational diagnosis assesses the security of the organization's activities. Diagnosis productive capacity is the basis for improvement of the organization's activities. Defined diagnostics of the production capacity of the organization. Justified the selection stages of the research production potential. The first stage is the preliminary diagnosis. The second stage provides for the rapid diagnosis of production potential. At the third stage it is advisable to perform problem diagnosis. Problem diagnosis consists of economic and organizational diagnosis. Economic diagnosis assesses the state of the elements of the production potential of the organization. Organizational diagnostics analyses provide productive capacity. The fourth stage is represented by the solution of the problems of utilization of production capacity. Each stage is considered, has its content and specific diagnostic methods of production potential. This method allows determining the state of the elements, the efficiency of utilization of production capacity. The estimation of the production potential is based on the application of utility theory. This assessment provides a definition of the criteria and the scale of usefulness. This will allow you to measure the production potential numerically. In the end, it is revealed

  1. The simple analytical method for scattered radiation calculation in contrast X-ray diagnostic techniques

    Energy Technology Data Exchange (ETDEWEB)

    Markovic, S; Pavlovic, R [Inst. of Nuclear Science Vinca, Belgrade (Yugoslavia). Radiation and Environmental Protection Lab.; Boreli, F [Fac. of Electrical Engineering, Belgrade (Yugoslavia)

    1996-12-31

    In realization of radiation protection measures for medical staff present during diagnostic procedures, the necessary condition is knowledge of the space - energy distributions of the scattered radiation from the patient. In this paper, the simple calculation procedure for the scattered radiation field of the actual diagnostic energies is presented. Starting from the single Compton scattering model and using the justified transformations the final equations in elementary form are derived. For numerical calculations the computer code ANGIO was created. The calculated results were confirmed by detailed dosimetric measurements of the scattered field around patient (the water phantom) in SSDL in the Institute of nuclear sciences `Vinca`, Belgrade. These results are good base for assessment of irradiation. The main irradiation source for the physician and the other members of the medical team is the back scattered radiation from patient - albedo. (author). 3 figs., 3 refs.

  2. A novelty detection diagnostic methodology for gearboxes operating under fluctuating operating conditions using probabilistic techniques

    Science.gov (United States)

    Schmidt, S.; Heyns, P. S.; de Villiers, J. P.

    2018-02-01

    In this paper, a fault diagnostic methodology is developed which is able to detect, locate and trend gear faults under fluctuating operating conditions when only vibration data from a single transducer, measured on a healthy gearbox are available. A two-phase feature extraction and modelling process is proposed to infer the operating condition and based on the operating condition, to detect changes in the machine condition. Information from optimised machine and operating condition hidden Markov models are statistically combined to generate a discrepancy signal which is post-processed to infer the condition of the gearbox. The discrepancy signal is processed and combined with statistical methods for automatic fault detection and localisation and to perform fault trending over time. The proposed methodology is validated on experimental data and a tacholess order tracking methodology is used to enhance the cost-effectiveness of the diagnostic methodology.

  3. Application of the SWE-to-PWE antenna diagnostics technique to an offset reflector antenna

    DEFF Research Database (Denmark)

    Cappellin, Cecilia; Frandsen, Aksel; Breinbjerg, Olav

    2008-01-01

    Electrical and mechanical errors in an antenna may seriously affect the antenna's performance. Although their presence is usually detected by anomalies in the antenna's far-field pattern, their identification is normally possible only through an analysis of the antenna's extreme near field....... The reconstruction of the extreme near field on the basis of near- or far-field measurements is thus an essential step in antenna diagnostics....

  4. Diagnostic Accuracy of Imaging Modalities and Injection Techniques for the Diagnosis of Femoroacetabular Impingement/Labral Tear

    DEFF Research Database (Denmark)

    Reiman, Michael P.; Thorborg, Kristian; Goode, Adam P.

    2017-01-01

    Background: Diagnosing femoroacetabular impingement/acetabular labral tear (FAI/ALT) and subsequently making a decision regarding surgery are based primarily on diagnostic imaging and intra-articular hip joint injection techniques of unknown accuracy. Purpose: Summarize and evaluate the diagnostic...... probability of disease was demonstrated. Positive imaging findings increased the probability that a labral tear existed by a minimal to small degree with the use of magnetic resonance imaging/magnetic resonance angiogram (MRI/MRA) and ultrasound (US) and by a moderate degree for CTA. Negative imaging findings...... decreased the probability that a labral tear existed by a minimal degree with the use of MRI and US, a small to moderate degree with MRA, and a moderate degree with CTA. Clinical Relevance: Although findings of the included studies suggested potentially favorable use of these modalities for the diagnosis...

  5. Comparison of advanced optical imaging techniques with current otolaryngology diagnostics for improved middle ear assessment (Conference Presentation)

    Science.gov (United States)

    Nolan, Ryan M.; Shelton, Ryan L.; Monroy, Guillermo L.; Spillman, Darold R.; Novak, Michael A.; Boppart, Stephen A.

    2016-02-01

    Otolaryngologists utilize a variety of diagnostic techniques to assess middle ear health. Tympanometry, audiometry, and otoacoustic emissions examine the mobility of the tympanic membrane (eardrum) and ossicles using ear canal pressure and auditory tone delivery and detection. Laser Doppler vibrometry provides non-contact vibrational measurement, and acoustic reflectometry is used to assess middle ear effusion using sonar. These technologies and techniques have advanced the field beyond the use of the standard otoscope, a simple tissue magnifier, yet the need for direct visualization of middle ear disease for superior detection, assessment, and management remains. In this study, we evaluated the use of portable optical coherence tomography (OCT) and pneumatic low-coherence interferometry (LCI) systems with handheld probe delivery to standard tympanometry, audiometry, otoacoustic emissions, laser Doppler vibrometry, and acoustic reflectometry. Comparison of these advanced optical imaging techniques and current diagnostics was conducted with a case study subject with a history of unilateral eardrum trauma. OCT and pneumatic LCI provide novel dynamic spatiotemporal structural data of the middle ear, such as the thickness of the eardrum and quantitative detection of underlying disease pathology, which could allow for more accurate diagnosis and more appropriate management than currently possible.

  6. Using technique vibration diagnostics for assessing the quality of power transmission line supports repairs

    Directory of Open Access Journals (Sweden)

    Cherpakov Aleksander

    2017-01-01

    Full Text Available The considered method for assessing the quality of the repair work to restore the rack supports of transmission lines is based on the method of vibration diagnostics. Power transmission line supports with a symmetrical destruction of the protective layer of concrete in the ground in violation of the construction section were chosen as an object. Finite element modelling package Ansys was used in assessing the quality of repair work. The example of evaluating the quality of repair using the relative adhesion defective area design criteria in the analysis of natural vibration frequencies is given.

  7. Intercomparison of techniques for inspection and diagnostics of heavy water reactor pressure tubes: Flaw detection and characterization [Phase 1

    International Nuclear Information System (INIS)

    2006-05-01

    Nuclear power plants with heavy water reactors (HWRs) comprise nine percent of today's operating nuclear units, and more are under construction. Efficient and accurate inspection and diagnostic techniques for various reactor components and systems are an important factor in assuring reliable and safe plant operation. To foster international collaboration in the efficient and safe use of nuclear power, the IAEA conducted a Coordinated Research Programme (CRP) on Inter-comparison of Techniques for HWR Pressure Tube Inspection and Diagnostics. This CRP was carried out within the frame of the IAEA Department of Nuclear Energy's Technical Working Group on Advanced Technologies for HWRs (the TWG-HWR). The TWG-HWR is a group of experts nominated by their governments and designated by the IAEA to provide advice and to support implementation of the IAEA's project on advanced technologies for HWRs. The objective of the CRP was to inter-compare non-destructive inspection and diagnostic techniques, in use and being developed, for structural integrity assessment of HWR pressure tubes. During the first phase of this CRP, participants have investigated the capability of different techniques to detect and characterize flaws. During the second phase of this CRP, participants collaborated to detect and characterize hydride blisters and to determine the hydrogen concentration in Zirconium alloys. The intent was to identify the most effective pressure tube inspection and diagnostic methods, and to identify further development needs. The organizations that have participated in this CRP are: - The Comision Nacional de Energia Atomica (CNEA), Argentina; - Atomic Energy of Canada Ltd. (AECL); Chalk River Laboratories (CRL), Canada; - The Research Institute of Nuclear Power Operations (RINPO), China National Nuclear Corporation (CNNC), China; - Bhabha Atomic Research Centre (BARC), India; - The Korea Electric Power Research Institute (KEPRI), Republic of Korea; - The Korea Atomic Energy

  8. Pocket book on setting techniques for medical imaging. X-ray diagnostics, angiography, CT, MRT. 4. rev. and enl. ed.; Taschenatlas Einstelltechnik. Roentgendiagnostik, Angiografie, CT, MRT

    Energy Technology Data Exchange (ETDEWEB)

    Moeller, Torsten B.; Reif, Emil [Caritas-Krankenhaus, Dillingen/Saar (Germany)

    2009-07-01

    The pocketbook on setting techniques for medical imaging is concerned with the problem to prepare appropriate images for diagnostic purposes using modern high-technology instruments like x-ray diagnostics, angiography, computerized tomography and magnetic resonance tomography. The following issues are covered: Head, spinal column, upper extremities, lower extremities, thorax, gastrointestinal tract, intravenous organ examination, angiography, computerized tomography, NMR imaging.

  9. Improvement of diagnostic techniques and electrical circuit in azo dye degradation by high voltage electrical discharge

    International Nuclear Information System (INIS)

    Shen Yongjun; Lei Lecheng; Zhang Xingwang; Zhou Minghua; Zhang Yi

    2008-01-01

    Fast electrical diagnostics and improvement of electrical circuits for methyl orange (MO) degradation by high voltage pulsed electrical discharge were investigated. To eliminate electromagnetic radiation, several effective methods were employed. RG 218 coaxial cable was substituted for the common transmission lines to transmit high voltage pulses, and multi-lines in parallel were earthed to avoid electromagnetic interference and, additionally, to reduce the stray inductance of the electrical circuit and increase the pulse rise rate to reduce the energy losses in the transmission system. The problem of the differences in the bandwidths of voltage and current probes causing an error in the calculation of energy dissipation was avoided by reducing the bandwidths of voltage and current measurements to the same value. The real discharge current was obtained by subtracting the capacitive current from the total current. The energy per pulse obtained in the reactor before and after improvement of the diagnostics and electrical circuit were 15.5 mJ and 26.8 mJ, respectively, and the energy efficiencies of MO degradation were 1.34 x 10 -9 mol/J and 1.95 x 10 -9 mol/J, respectively

  10. An efficient diagnostic technique for distribution systems based on under fault voltages and currents

    Energy Technology Data Exchange (ETDEWEB)

    Campoccia, A.; Di Silvestre, M.L.; Incontrera, I.; Riva Sanseverino, E. [Dipartimento di Ingegneria Elettrica elettronica e delle Telecomunicazioni, Universita degli Studi di Palermo, viale delle Scienze, 90128 Palermo (Italy); Spoto, G. [Centro per la Ricerca Elettronica in Sicilia, Monreale, Via Regione Siciliana 49, 90046 Palermo (Italy)

    2010-10-15

    Service continuity is one of the major aspects in the definition of the quality of the electrical energy, for this reason the research in the field of faults diagnostic for distribution systems is spreading ever more. Moreover the increasing interest around modern distribution systems automation for management purposes gives faults diagnostics more tools to detect outages precisely and in short times. In this paper, the applicability of an efficient fault location and characterization methodology within a centralized monitoring system is discussed. The methodology, appropriate for any kind of fault, is based on the use of the analytical model of the network lines and uses the fundamental components rms values taken from the transient measures of line currents and voltages at the MV/LV substations. The fault location and identification algorithm, proposed by the authors and suitably restated, has been implemented on a microprocessor-based device that can be installed at each MV/LV substation. The speed and precision of the algorithm have been tested against the errors deriving from the fundamental extraction within the prescribed fault clearing times and against the inherent precision of the electronic device used for computation. The tests have been carried out using Matlab Simulink for simulating the faulted system. (author)

  11. Diagnostic and corrective procedures for TL analysis using the pre-dose technique

    International Nuclear Information System (INIS)

    Haskell, E.H.

    1985-01-01

    The high sensitivity of the pre-dose TL technique using fired quartz grains with relatively low doses makes it the only TL technique that is generally suitable for retrospective environmental dosimetry. The use of this technique for dose measurements of less than 0.2 Gy has been the focus of research at the Utah laboratory, while the extension of the useful range of the pre-dose technique to doses in excess of 5 Gy has been the aim of the Durham laboratory. Certain characteristics of the pre-dose phenomenon, if not properly diagnosed, can lead to erroneous dose estimates at both extremes. This paper describes the procedures used at both laboratories to diagnose such problems and recently developed methods for their circumvention. (author)

  12. A Roadmap of Risk Diagnostic Methods: Developing an Integrated View of Risk Identification and Analysis Techniques

    National Research Council Canada - National Science Library

    Williams, Ray; Ambrose, Kate; Bentrem, Laura

    2004-01-01

    ...), which is envisioned to be a comprehensive reference tool for risk identification and analysis (RI AND A) techniques. Program Managers (PMs) responsible for developing or acquiring software-intensive systems typically identify risks in different ways...

  13. Do Anesthetic Techniques Influence the Threshold for Glomerular Capillary Hemorrhage Induced in Rats by Contrast-Enhanced Diagnostic Ultrasound?

    Science.gov (United States)

    Miller, Douglas L; Lu, Xiaofang; Fabiilli, Mario; Dou, Chunyan

    2016-02-01

    Glomerular capillary hemorrhage can be induced by ultrasonic cavitation during contrast-enhanced diagnostic ultrasound (US) exposure, an important nonthermal US bioeffect. Recent studies of pulmonary US exposure have shown that thresholds for another nonthermal bioeffect of US, pulmonary capillary hemorrhage, is strongly influenced by whether xylazine is included in the specific anesthetic technique. The objective of this study was to determine the influence of xylazine on contrast-enhanced diagnostic US-induced glomerular capillary hemorrhage. In this study, anesthesia with ketamine only was compared to ketamine plus xylazine for induction of glomerular capillary hemorrhage in rats by 1.6-MHz intermittent diagnostic US with a microsphere contrast agent (similar to Definity; Lantheus Medical Imaging, Inc, North Billerica, MA). Glomerular capillary hemorrhage was measured as a percentage of glomeruli with hemorrhage found in histologic sections for groups of rats scanned at different peak rarefactional pressure amplitudes. There was a significant difference between the magnitude of the glomerular capillary hemorrhage between the anesthetics at 2.3 MPa, with 45.6% hemorrhage for ketamine only, increasing to 63.2% hemorrhage for ketamine plus xylazine (P Ultrasound in Medicine.

  14. Development of reactor accident diagnostic system DISKET using knowledge engineering technique

    International Nuclear Information System (INIS)

    Yokobayashi, Masao; Yoshida, Kazuo; Kohsaka, Atsuo; Yamamoto, Minoru.

    1986-01-01

    An accident diagnostic system DISKET has been developed to identify the cause and the type of an abnormal transient of a nuclear power plant. The system is based on the knowledge engineering (KE) and consists of an inference engine IERIAS and a knowledge base. The main features of DISKET are the following : (1) Time-varying characteristics of transients can be treated. (2) Knowledge base can be divided into several knowledge units to handle a lot of rules effectively. (3) Programming language UTILISP, which is a dialect of LISP, is used to manipulate symbolic data effectively. For the verification of DISKET, performance tests have been conducted for several types of accidents. The knowledge base used in the tests was generated from the data of various types of transients produced by a PWR plant simulator. The results of verification studies showed a good applicability of DISKET to reactor accident diagnosis. (author)

  15. Diagnostic prénatal: quelles sont les techniques actuelles et futures ? (flyer)

    CERN Multimedia

    2002-01-01

    La majorité des bébés qui viennent au monde ne présentent pas d'anomalies particulières. Cependant, il faut savoir qu'environ 1 foetus 170 présente une anomalie chromosomique (défaut de la structure ou du nombre de chromosomes) qui va peser plus ou moins lourdement sur sa vie future et 1 foetus sur 100 présente une maladie génique due à un changement dans un gène. Le diagnostic prénatal a connu et connaît une formidable expansion grâce aux progrès technologiques en génétique et imagerie foetale.

  16. The integration of novel diagnostics techniques for multi-scale monitoring of large civil infrastructures

    Directory of Open Access Journals (Sweden)

    F. Soldovieri

    2008-11-01

    Full Text Available In the recent years, structural monitoring of large infrastructures (buildings, dams, bridges or more generally man-made structures has raised an increased attention due to the growing interest about safety and security issues and risk assessment through early detection. In this framework, aim of the paper is to introduce a new integrated approach which combines two sensing techniques acting on different spatial and temporal scales. The first one is a distributed optic fiber sensor based on the Brillouin scattering phenomenon, which allows a spatially and temporally continuous monitoring of the structure with a "low" spatial resolution (meter. The second technique is based on the use of Ground Penetrating Radar (GPR, which can provide detailed images of the inner status of the structure (with a spatial resolution less then tens centimetres, but does not allow a temporal continuous monitoring. The paper describes the features of these two techniques and provides experimental results concerning preliminary test cases.

  17. Risk estimation in association with diagnostic techniques in the nuclear medicine service of the Camaguey Ciego de Avila Territory

    International Nuclear Information System (INIS)

    Barrerras, C.A.; Brigido, F.O.; Naranjo, L.A.; Lasserra, S.O.; Hernandez Garcia, J.

    1999-01-01

    The nuclear medicine service at the Maria Curie Oncological Hospital, Camaguey, has experience of over three decades in using radiofarmaceutical imaging agents for diagnosis. Although the clinical risk associated with these techniques is negligible, it is necessary to evaluate the effective dose administered to the patient due to the introduction of radioactive substances into the body. The study of the dose administered to the patient provides useful data for evaluating the detriment associated with this medical practice, its subsequently optimization and consequently, for minimizing the stochastic effects on the patient. The aim of our paper is to study the collective effective dose administered by nuclear medicine service to Camaguey and Ciego de Avila population from 1995 to 1998 and the relative contribution to the total annual effective collective dose of the different diagnostic examinations. The studies were conducted on the basis of statistics from nuclear medicine examinations given to a population of 1102353 inhabitants since 1995. The results show that the nuclear medicine techniques of neck examinations with 1168.8 Sv man (1.11 Sv/expl), thyroid explorations with 119.6 Sv man (55.5 mSv/expl) and iodide uptake with 113.7 Sv man (14.0 mSv/expl) are the main techniques implicated in the relative contribution to the total annual effective collective dose of 1419.5 Sv man. The risk estimation in association with diagnostic techniques in the nuclear medicine service studied is globally low (total detriment: 103.6 as a result of 16232 explorations), similar to other published data

  18. Critical evaluation of fine needle aspiration cytology as a diagnostic technique in bone tumors and tumor-like lesions.

    Science.gov (United States)

    Chakrabarti, Sudipta; Datta, Alok Sobhan; Hira, Michael

    2012-01-01

    Though open surgical biopsy is the procedure of choice for the diagnosis of bone tumors, many disadvantages are associated with this approach. The present study was undertaken to evaluate the role of fine needle aspiration cytology (FNAC) as a diagnostic tool in cases of bony tumors and tumor-like lesions which may be conducted in centers where facilities for surgical biopsies are inadequate. The study population consisted of 51 cases presenting with a skeletal mass. After clinical evaluation, radiological correlation was done to assess the nature and extent of each lesion. Fine needle aspiration was performed aseptically and smears were prepared. Patients subsequently underwent open surgical biopsy and tissue samples were obtained for histopathological examination. Standard statistical methods were applied for analysis of data. Adequate material was not obtained even after repeated aspiration in seven cases, six of which were benign. Among the remaining 44 cases, diagnosis of malignancy was correctly provided in 28 (93.3%) out of 30 cases and categorical diagnosis in 20 (66.67%). Interpretation of cytology was more difficult in cases of benign and tumor-like lesions, with a categorical opinion only possible in seven (50%) cases. Statistical analysis showed FNAC with malignant tumors to have high sensitivity (93.3%), specificity (92.9%) and positive predictive value of 96.6%, whereas the negative predictive value was 86.7%. FNAC should be included in the diagnostic workup of a skeletal tumor because of its simplicity and reliability. However, a definitive pathologic diagnosis heavily depends on compatible clinical and radiologic features which can only be accomplished by teamwork. The cytological technique applied in this study could detect many bone tumors and tumor-like conditions and appears particularly suitable as a diagnostic technique for rural regions of India as other developing countries.

  19. Diagnostic technique for measuring fusion reaction rate for inertial confinement fusion experiments at Shen Guang-III prototype laser facility

    International Nuclear Information System (INIS)

    Wang Feng; Peng Xiao-Shi; Liu Shen-Ye; Xu Tao; Kang Dong-Guo

    2013-01-01

    A study is conducted using a two-dimensional simulation program (Lared-s) with the goal of developing a technique to evaluate the effect of Rayleigh-Taylor growth in a neutron fusion reaction region. Two peaks of fusion reaction rate are simulated by using a two-dimensional simulation program (Lared-s) and confirmed by the experimental results. A neutron temporal diagnostic (NTD) system is developed with a high temporal resolution of ∼ 30 ps at the Shen Guang-III (SG-III) prototype laser facility in China, to measure the fusion reaction rate history. With the shape of neutron reaction rate curve and the spherical harmonic function in this paper, the degree of Rayleigh-Taylor growth and the main source of the neutron yield in our experiment can be estimated qualitatively. This technique, including the diagnostic system and the simulation program, may provide important information for obtaining a higher neutron yield in implosion experiments of inertial confinement fusion

  20. A thermal technique for local ultrasound intensity measurement: part 2. Application to exposimetry on a medical diagnostic device

    International Nuclear Information System (INIS)

    Wilkens, V

    2010-01-01

    Acoustic output measurements on medical ultrasound equipment are usually performed using radiation force balances to determine the output power and using hydrophones to determine pressure and intensity parameters. The local temporal-average ultrasound intensity can be measured alternatively by thermal sensors. The technique was described and prototype sensors were characterized in a preceding paper. Here, the application of such a thermal intensity sensor to the output beam characterization of a typical medical diagnostic device is described. Two transducers, a 7.5 MHz linear array and a 3.5 MHz convex array were investigated in different operating modes. For comparison, hydrophone measurements were also performed. If the spatial averaging effect is taken into account, good agreement is found between both measurement methods. The maximum deviations of the spatial-peak temporal-average intensities I SPTA obtained with the thermal sensor from the corresponding hydrophone-based results were below 12%. The simple thermal technique offers advantages for intensity measurements especially in the case of scanning and combined modes of the diagnostic device, where the synchronization between hydrophone measurements and the complex pulse emission pattern can be difficult

  1. An Experimental Technique for Structural Diagnostic Based on Laser Vibrometry and Neural Networks

    Directory of Open Access Journals (Sweden)

    Paolo Castellini

    2000-01-01

    Full Text Available In recent years damage detection techniques based on vibration data have been largely investigated with promising results for many applications. In particular, several attempts have been made to determine which kind of data should be extracted for damage monitoring.

  2. A Diagnostic Technique for Formulating Market Strategies in Higher Education Based on Relative Competitive Position.

    Science.gov (United States)

    Dolinsky, Arthur L.; Quazi, Hesan A.

    1994-01-01

    Importance-performance analysis, a marketing research technique using analysis of consumer attitudes toward salient product or service attributes, is found useful for colleges and universities in developing marketing strategies, particularly when competition is considered as an important dimension. Data are drawn from a survey of 252 students at 1…

  3. Office hysteroscopic-guided selective tubal chromopertubation: acceptability, feasibility and diagnostic accuracy of this new diagnostic non-invasive technique in infertile women.

    Science.gov (United States)

    Carta, Gaspare; Palermo, Patrizia; Pasquale, Chiara; Conte, Valeria; Pulcinella, Ruggero; Necozione, Stefano; Cofini, Vincenza; Patacchiola, Felice

    2018-06-01

    The aim of this study was to evaluate accuracy, tolerability and side effects of office hysteroscopic-guided chromoperturbations in infertile women without anaesthesia. Forty-nine infertile women underwent the procedure to evaluate tubal patency and the uterine cavity. Women with unilateral or bilateral tubal stenosis at hysteroscopy with chromoperturbation, and women with bilateral tubal patency who did not conceive during the period of six months, underwent laparoscopy with chromoperturbation. The results obtained from hysteroscopy and laparoscopy in the assessment of tubal patency were compared. Sensitivity, specificity, accuracy, positive-predictive value and negative-predictive value were used to describe diagnostic performance. Pain and tolerance were assessed during procedure using a visual analogue scale (VAS). Side effects or late complications and pregnancy rate were also recorded three and six months after the procedure. The specificity was 87.8% (95% CI: 73.80-95.90), sensitivity was 85.7% (95% CI 57.20-98.20), positive and negative predictive values were 70.6% (95% CI: 44.00-89) and 94.7% (95% CI: 82.30-99.40), respectively. Pregnancy rate (PR) within six months after performance of hysteroscopy with chromoperturbation was 27%. Office hysteroscopy-guided selective chromoperturbation in infertile patients is a valid technique to evaluate tubal patency and uterine cavity.

  4. Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis.

    Science.gov (United States)

    Vang, Russell; Gupta, Mamta; Wu, Lee-Shu-Fune; Yemelyanova, Anna V; Kurman, Robert J; Murphy, Kathleen M; Descipio, Cheryl; Ronnett, Brigitte M

    2012-03-01

    Distinction of hydatidiform moles (HMs) from nonmolar specimens (NMs) and subclassification of HMs as complete hydatidiform moles (CHMs) and partial hydatidiform moles (PHMs) are important for clinical practice and investigational studies; yet, diagnosis based solely on morphology is affected by interobserver variability. Molecular genotyping can distinguish these entities by discerning androgenetic diploidy, diandric triploidy, and biparental diploidy to diagnose CHMs, PHMs, and NMs, respectively. Eighty genotyped cases (27 CHMs, 27 PHMs, and 26 NMs) were selected from a series of 200 potentially molar specimens previously diagnosed using p57 immunostaining and genotyping. Cases were classified by 3 gynecologic pathologists on the basis of H&E slides (masked to p57 immunostaining and genotyping results) into 1 of 3 categories (CHM, PHM, or NM) during 2 diagnostic rounds; a third round incorporating p57 immunostaining results was also conducted. Consensus diagnoses (those rendered by 2 of 3 pathologists) were determined. Genotyping results were used as the gold standard for assessing diagnostic performance. Sensitivity of a diagnosis of CHM ranged from 59% to 100% for individual pathologists and from 70% to 81% by consensus; specificity ranged from 91% to 96% for individuals and from 94% to 98% by consensus. Sensitivity of a diagnosis of PHM ranged from 56% to 93% for individual pathologists and from 70% to 78% by consensus; specificity ranged from 58% to 92% for individuals and from 74% to 85% by consensus. The percentage of correct classification of all cases by morphology ranged from 55% to 75% for individual pathologists and from 70% to 75% by consensus. The κ values for interobserver agreement ranged from 0.59 to 0.73 (moderate to good) for a diagnosis of CHM, from 0.15 to 0.43 (poor to moderate) for PHM, and from 0.13 to 0.42 (poor to moderate) for NM. The κ values for intraobserver agreement ranged from 0.44 to 0.67 (moderate to good). Addition of the p57

  5. Gel instillation sonohysterography (GIS) and saline contrast sonohysterography (SCSH): comparison of two diagnostic techniques.

    Science.gov (United States)

    Bij de Vaate, A J M; Brölmann, H A M; van der Slikke, J W; Emanuel, M H; Huirne, J A F

    2010-04-01

    To compare gel instillation sonohysterography (GIS) with saline contrast sonohysterography (SCSH) as diagnostic methods for the evaluation of the uterine cavity. A prospective cohort study was performed at the Department of Obstetrics and Gynecology of the VU University Medical Center, Amsterdam, between September 2007 and April 2008. We included 65 women suspected of having an intrauterine abnormality with an indication for SCSH/GIS. First SCSH and subsequently GIS were performed in all women. Distension of the uterine cavity, image quality, visualization of intrauterine abnormalities and pain experienced on a visual analog scale (VAS score) were recorded for both procedures. The mean distension with GIS was 9.0 mm and with SCSH it was 8.5 mm (P = 0.15). The mean image quality, on a scale from 0 to 5, for SCSH was 4.0 and for GIS it was 3.6 (P = 0.01). No difference was found for the visualization of intrauterine abnormalities, and the VAS scores for pain experienced on SCSH and GIS were 1.5 and 1.6, respectively (P = 0.62). The image quality of SCSH is slightly better than that of GIS. This difference is likely to be attributable to the presence of air bubbles in the gel. The small difference in uterine cavity distension in favor of GIS and comparable stable distension during at least 4 min make GIS a suitable alternative for SCSH if air bubbles can be prevented. Copyright 2009 ISUOG. Published by John Wiley & Sons, Ltd.

  6. Thermometric diagnosis of peripheral nerve injuries. Assessment of the diagnostic accuracy of a new practical technique.

    Science.gov (United States)

    Ya'ish, F M M; Cooper, J P; Craigen, M A C

    2007-07-01

    The diagnosis of nerve injury using thermotropic liquid crystal temperature strips was compared blindly and prospectively against operative findings in 36 patients requiring surgical exploration for unilateral upper limb lacerations with suspected nerve injury. Thermotropic liquid crystal strips were applied to affected and non-affected segments in both hands in all subjects. A pilot study showed that a simple unilateral laceration without nerve injury results in a cutaneous temperature difference between limbs, but not within each limb. Thus, for detection of a nerve injury, comparison was made against the unaffected nerve distribution in the same hand. Receiver operating characteristic curve analysis showed that an absolute temperature difference > or = 1.0 degrees C was diagnostic of a nerve injury (area under the curve = 0.985, sensitivity = 100%, specificity = 93.8%). Thermotropic liquid crystal strip assessment is a new, reliable and objective method for the diagnosis of traumatic peripheral nerve injuries. If implemented in the acute setting, it could improve the reliability of clinical assessment and reduce the number of negative surgical explorations.

  7. Use of serological diagnostic techniques in the control and eradication of caprine arthritis encephalitis: an update

    Directory of Open Access Journals (Sweden)

    Jamili Maria Suhet Mussi

    2015-12-01

    Full Text Available Caprine arthritis encephalitis (CAE is a chronic disease caused by a small ruminant lentivirus (SRLV, which causes significant losses in goat breeding. The actual state of animal infection with SRLV is difficult to determine due to a complex pathogenesis of the virus, including factors such as delayed or intermittent seroconversion in serological tests. Several serological techniques are available for disease diagnosis, such as screening or confirmation tests, which are different in sensitivity and specificity. Regarding the choice of the test to be applied, availability of commercial immunoreagents, team training, antigen used, and cost of techniques must be considered. This review presents the serological methods available for use in different stages of CAE control and eradication programs, and management measures to be adopted in conjunction with serological diagnosis of the disease.

  8. Diagnosis of soil-transmitted helminthiasis in an Amazonic community of Peru using multiple diagnostic techniques.

    Science.gov (United States)

    Machicado, Jorge D; Marcos, Luis A; Tello, Raul; Canales, Marco; Terashima, Angelica; Gotuzzo, Eduardo

    2012-06-01

    An observational descriptive study was conducted in a Shipibo-Conibo/Ese'Eja community of the rainforest in Peru to compare the Kato-Katz method and the spontaneous sedimentation in tube technique (SSTT) for the diagnosis of intestinal parasites as well as to report the prevalence of soil-transmitted helminth (STH) infections in this area. A total of 73 stool samples were collected and analysed by several parasitological techniques, including Kato-Katz, SSTT, modified Baermann technique (MBT), agar plate culture, Harada-Mori culture and the direct smear examination. Kato-Katz and SSTT had the same rate of detection for Ascaris lumbricoides (5%), Trichuris trichiura (5%), hookworm (14%) and Hymenolepis nana (26%). The detection rate for Strongyloides stercoralis larvae was 16% by SSTT and 0% by Kato-Katz, but 18% by agar plate culture and 16% by MBT. The SSTT also had the advantage of detecting multiple intestinal protozoa such as Blastocystis hominis (40%), Giardia intestinalis (29%) and Entamoeba histolytica/E. dispar (16%). The most common intestinal parasites found in this community were B. hominis, G. intestinalis, H. nana, S. stercoralis and hookworm. In conclusion, the SSTT is not inferior to Kato-Katz for the diagnosis of common STH infections but is largely superior for detecting intestinal protozoa and S. stercoralis larvae. Copyright © 2012 Royal Society of Tropical Medicine and Hygiene. Published by Elsevier Ltd. All rights reserved.

  9. Analysis of relaxing laser-induced plasmas by absorption spectroscopy: Toward a new quantitative diagnostic technique

    International Nuclear Information System (INIS)

    Ribiere, M.; Cheron, B.G.

    2010-01-01

    Broad-band near UV absorption spectroscopy was used to analyze atmospheric laser-induced plasmas formed on metallic and refractory targets. When the common emission spectroscopy only provides the density of the radiating atomic excited states, the technique reported in this paper is able to achieve high spatial resolution in the measurement of absolute number densities in expanding laser-induced plasmas. The reliability and the versatility of this technique, which is based on the comparison between results of the numerical integration of the radiative transfer equation and experimental spectra, were tested on different targets. The evolutions in time and space of the absolute population of the plasma species originating from metallic alloys (Al-Mg and Cu-Ni) and refractory materials (C/SiC) were achieved over large time scales. Owing to its accuracy, this absorption technique (that we call 'LIPAS' for Laser Induced Plasma Absorption Spectroscopy) should bring a new and enhanced support to the validation of collisional-radiative models attempting to provide reliable evolutions of laser-induced plasmas.

  10. New diagnostic and therapeutic techniques in the management of pyogenic liver abscesses

    International Nuclear Information System (INIS)

    Ranson, J.H.C.; Madayag, M.A.; Localio, S.A.; Spencer, F.C.

    1975-01-01

    An unexplained increase in the frequency of pyogenic liver abscesses of unknown etiology has, fortunately, been paralleled by significant advances in diagnostic and therapeutic methods. This report reviews experience with 14 patients operated upon at NYU Medical Center since 1971. Eight cases (57 percent) were cryptogenic. Other abscesses were associated with biliary disease (3); abdominal sepsis (2); and trauma (1). Abscesses were present on hospitalization in 12 patients. Clinical findings included fever (101 to 108 F), 100 percent; leucocytosis, 71 percent; anorexia and vomiting, 50 percent; localized tenderness and hepatomegaly, 50 percent; hypoalbuminemia; 86 percent; hypocholesterolemia, 78 percent; elevated SGOT, 71 percent; and elevated aikaline phosphatase, 43 percent. Technetium hepatic scintiscans showed focal defects in 10 of 12 patients (83 percent), but did not detect multiple abscesses in 2 of these. Hepatic arteriography performed in 10 patients was highly accurate, outlining single abscesses in 6 and multiple abscesses in 4. Furthermore, in one patient a false positive scintiscan was demonstrated by negative arteriography, confirmed by autopsy. In 4 patients, arteriography indicated an abscess in the posterior-superior area of the right hepatic lobe. With precise anatomical localization, a transthoracic approach permitted uncomplicated drainage in each case. This approach provides excellent exposure and direct drainage for abscesses in this area. An additional therapeutic adjunct in two patients, with 4 and 11 abscesses each, was postoperative intraportal infusion of antibiotics through the umbilical vein. Thirteen patients (83 percent) recovered, one dying from pulmonary embolism. Primary hepatic abscesses occur with increasing frequency. The methods described allow more precise preoperative diagnosis and direct surgical drainage

  11. Four-hour processing of clinical/diagnostic specimens for electron microscopy using microwave technique.

    Science.gov (United States)

    Giberson, R T; Demaree, R S; Nordhausen, R W

    1997-01-01

    A protocol for routine 4-hour microwave tissue processing of clinical or other samples for electron microscopy was developed. Specimens are processed by using a temperature-restrictive probe that can be set to automatically cycle the magnetron to maintain any designated temperature restriction (temperature maximum). In addition, specimen processing during fixation is performed in 1.7-ml microcentrifuge tubes followed by subsequent processing in flow-through baskets. Quality control is made possible during each step through the addition of an RS232 port to the microwave, allowing direct connection of the microwave oven to any personal computer. The software provided with the temperature probe enables the user to monitor time and temperature on a real-time basis. Tissue specimens, goat placenta, mouse liver, mouse kidney, and deer esophagus were processed by conventional and microwave techniques in this study. In all instances, the results for the microwave-processed samples were equal to or better than those achieved by routine processing techniques.

  12. Comparison of different diagnostic techniques for the detection of cryptosporidiosis in bovines

    Directory of Open Access Journals (Sweden)

    H. K. M. Rekha

    2016-02-01

    Full Text Available Aim: Aim of the present study was to compare different methods, viz., Sheather’s sugar flotation (SSF, Ziehl-Neelsen (ZN, Kinyoun’s acid-fast method (KAF, safranin-methylene blue staining (SMB, and negative staining techniques such as nigrosin staining, light green staining, and malachite green staining for the detection of Cryptosporidium spp. oocysts in bovines. Materials and Methods: A total of 455 fecal samples from bovines were collected from private, government farms and from the clinical cases presented to Department of Medicine, Veterinary College, Bengaluru. They were subjected for SSF, ZN, KAF, SMB and negative staining methods. Results: Out of 455 animal fecal samples screened 5.71% were found positive for Cryptosporidium spp. oocysts. The species were identified as Cryptosporidium parvum in calves and Cryptosporidium andersoni in adults based on the morphological characterization and micrometry of the oocysts. Conclusions: Of all the techniques, fecal flotation with sheather’s was found to be more specific and sensitive method for the detection of Cryptosporidium spp. oocysts. Among the conventional staining methods, the SMB gives better differentiation between oocysts and yeast. Among the three negative staining methods, malachite green was found sensitive over the other methods.

  13. Sensitivity of diagnostic techniques in determining the prevalence of anuran trypanosomes.

    Science.gov (United States)

    Woo, P T

    1983-01-01

    Two hundred thirty-three leopard frogs (Rana pipiens) from Oshkosh, Wisconsin, USA, were divided into two groups and their blood examined for trypanosomes. In Group I (n = 157), where the blood was examined by the hematocrit centrifuge technique (HCT), 36 (23%) were infected with trypanosomes. Eighteen were infected with Trypanosoma pipientis, 13 with Trypanosoma ranarum, three with Trypanosoma rotatorium and two with mixed infections of T. pipientis and T. ranarum. In Group II (n = 76) the blood was cultured and also examined by HCT and wet mounts. Trypanosomes (T. pipientis and T. ranarum) were detected in 24 frogs (33%) using all three techniques. Eleven T. pipientis were detected by HCT, however none by culture and two by wet mounts. Twelve T. ranarum were detected by culture while only 10 were found by HCT and five by wet mounts. One T. ranarum infection detected by HCT was missed by culture because of bacterial contamination. The HCT was consistently better than wet mount examinations. It is suggested that the HCT be used whenever possible in future trypanosome surveys.

  14. Diagnostic performance of MRI measurements to assess hindfoot malalignment. An assessment of four measurement techniques

    International Nuclear Information System (INIS)

    Buck, Florian M.; Hoffmann, Adrienne; Mamisch-Saupe, Nadja; Hodler, Juerg; Farshad, Mazda; Espinosa, Norman; Resnick, Donald

    2013-01-01

    To investigate the ability of coronal non-weight-bearing MR images to discriminate between normal and abnormal hindfoot alignment. Three different measurement techniques (calcaneal axis, medial/lateral calcaneal contour) based on weight-bearing hindfoot alignment radiographs were applied in 49 patients (mean, 48 years; range 21-76 years). Three groups of subjects were enrolled: (1) normal hindfoot alignment (0 -10 valgus); (2) abnormal valgus (>10 ); (3) any degree of varus hindfoot alignment. Hindfoot alignment was then measured on coronal MR images using four different measurement techniques (calcaneal axis, medial/lateral calcaneal contour, sustentaculum tangent). ROC analysis was performed to find the MR measurement with the greatest sensitivity and specificity for discrimination between normal and abnormal hindfoot alignment. The most accurate measurement on MR images to detect abnormal hindfoot valgus was the one using the medial calcaneal contour, reaching a sensitivity/specificity of 86 %/75 % using a cutoff value of >11 valgus. The most accurate measurement on MR images to detect abnormal hindfoot varus was the sustentaculum tangent, reaching a sensitivity/specificity of 91 %/71 % using a cutoff value of <12 valgus. It is possible to suspect abnormal hindfoot alignment on coronal non-weight-bearing MR images. (orig.)

  15. Towards non-invasive diagnostic techniques for early detection of acute renal transplant rejection: A review

    Directory of Open Access Journals (Sweden)

    Elizabeth Hollis

    2017-03-01

    Full Text Available The kidney is a very important complicated filtering organ of the body. When the kidney reaches stage 5 chronic kidney disease, end stage renal failure, the preeminent therapy is renal transplantation. Although it is the best form of treatment, lack of kidney donors is still challenging. Therefore, all efforts should be employed to prolong the survival rate of the transplanted kidney. However, graft dysfunction (e.g., acute rejection is one of the serious barriers to long term kidney transplant survival. Currently, graft dysfunction’s gold standard of diagnosis is renal biopsy. Although renal biopsy is helpful, it is not preferred due to its invasive nature, high morbidity rates, and expensiveness. Therefore, noninvasive imaging techniques have become the subject of extensive research and interest, giving a strong promise to replace, or at least to decrease, biopsy usage in diagnosing graft dysfunction. This survey will discuss not only the current diagnosis and treatment of graft dysfunction but also the state-of-the-art imaging techniques in detecting acute renal transplant rejection.

  16. Diagnostic performance of MRI measurements to assess hindfoot malalignment. An assessment of four measurement techniques

    Energy Technology Data Exchange (ETDEWEB)

    Buck, Florian M.; Hoffmann, Adrienne; Mamisch-Saupe, Nadja; Hodler, Juerg [University Hospital Balgrist and University of Zurich, Radiology, Zuerich (Switzerland); Farshad, Mazda; Espinosa, Norman [University Hospital Balgrist and University of Zurich, Department of Orthopaedic Surgery, Zuerich (Switzerland); Resnick, Donald [University of California San Diego, Department of Radiology, San Diego, CA (United States)

    2013-09-15

    To investigate the ability of coronal non-weight-bearing MR images to discriminate between normal and abnormal hindfoot alignment. Three different measurement techniques (calcaneal axis, medial/lateral calcaneal contour) based on weight-bearing hindfoot alignment radiographs were applied in 49 patients (mean, 48 years; range 21-76 years). Three groups of subjects were enrolled: (1) normal hindfoot alignment (0 -10 valgus); (2) abnormal valgus (>10 ); (3) any degree of varus hindfoot alignment. Hindfoot alignment was then measured on coronal MR images using four different measurement techniques (calcaneal axis, medial/lateral calcaneal contour, sustentaculum tangent). ROC analysis was performed to find the MR measurement with the greatest sensitivity and specificity for discrimination between normal and abnormal hindfoot alignment. The most accurate measurement on MR images to detect abnormal hindfoot valgus was the one using the medial calcaneal contour, reaching a sensitivity/specificity of 86 %/75 % using a cutoff value of >11 valgus. The most accurate measurement on MR images to detect abnormal hindfoot varus was the sustentaculum tangent, reaching a sensitivity/specificity of 91 %/71 % using a cutoff value of <12 valgus. It is possible to suspect abnormal hindfoot alignment on coronal non-weight-bearing MR images. (orig.)

  17. New analysis methods to push the boundaries of diagnostic techniques in the environmental sciences

    International Nuclear Information System (INIS)

    Lungaroni, M.; Peluso, E.; Gelfusa, M.; Malizia, A.; Talebzadeh, S.; Gaudio, P.; Murari, A.; Vega, J.

    2016-01-01

    In the last years, new and more sophisticated measurements have been at the basis of the major progress in various disciplines related to the environment, such as remote sensing and thermonuclear fusion. To maximize the effectiveness of the measurements, new data analysis techniques are required. First data processing tasks, such as filtering and fitting, are of primary importance, since they can have a strong influence on the rest of the analysis. Even if Support Vector Regression is a method devised and refined at the end of the 90s, a systematic comparison with more traditional non parametric regression methods has never been reported. In this paper, a series of systematic tests is described, which indicates how SVR is a very competitive method of non-parametric regression that can usefully complement and often outperform more consolidated approaches. The performance of Support Vector Regression as a method of filtering is investigated first, comparing it with the most popular alternative techniques. Then Support Vector Regression is applied to the problem of non-parametric regression to analyse Lidar surveys for the environments measurement of particulate matter due to wildfires. The proposed approach has given very positive results and provides new perspectives to the interpretation of the data.

  18. [A study of the value of three molecular diagnostic techniques in the diagnosis of tuberculosis].

    Science.gov (United States)

    Huang, Fang; Dang, Liyun; Sun, Huiping; Yang, Han; Wu, Xia

    2015-09-01

    To evaluate the diagnostic value of real-time fluorescent RNA isothermal amplification detection technology (simultaneous amplification and testing, SAT), Mycobacterium nucleic acid detection (PCR-fluorescence probe)method (TB-NTM-PCR) and Xpert MTB/RIF detection in the diagnosis of tuberculosis. A total of 378 sputum specimens from pulmonary tuberculosis patients were collected between April to July 2014 in Xi'an Thoracic Tumor and Tuberculosis Hospital. The specimens were detected by 5 methods at the same time including acid-fast stain, SAT method, TB-NTM-PCR method, TB 960 rapid liquid culture and Xpert MTB/RIF. The sensitivity and specificity of SAT method, TB-NTM-PCR method and Xpert MTB/RIF were calculated according to the results of TB 960 rapid liquid culture and staining. The difference among all the 3 methods was analyzed by Chi-squared test. The positive rate of SAT-TB,TB-NTM-PCR and Xpert MTB/RIF were 37.6% (142/378), 37.8% (143/378) and 53.4% (202/378), respectively. In specimens both positive for acid-fast stain and culture, the positive rate of SAT method was 84.6% (77/91), that of TB-NTM-PCR was 91.2% (83/91), and that of Xpert MTB/RIF was 96.7% (88/91), the difference being significant (P=0.018 2). In specimens negative for acid-fast stain but positive for culture, the positive rate of SAT method was 61.9% (60 /97), that of TB-NTM-PCR was 44.3% (43/97), and that of Xpert MTB/RIF was 80.4% (78/97), the difference being significant (Pmolecular detection methods showed good results for the auxiliary diagnosis of tuberculosis. Xpert MTB/RIF had the best performance both in smear positive and negative specimens and it can detect rifampicin related rpoB gene mutations at the same time.

  19. MR-defecography in obstructed defecation syndrome (ODS): technique, diagnostic criteria and grading.

    Science.gov (United States)

    Piloni, V; Tosi, P; Vernelli, M

    2013-10-01

    The aim of this study was to evaluate the use of a magnetic resonance (MR)-based classification system of obstructive defecation syndrome (ODS) to guide physicians in patient management. The medical records and imaging series of 105 consecutive patients (90 female, 15 male, aged 21-78 years, mean age 46.1 ± 5.1 years) referred to our center between April 2011 and January 2012 for symptoms of ODS were retrospectively examined. After history taking and a complete clinical examination, patients underwent MR imaging according to a standard protocol using a 0.35 T permanent field, horizontally oriented open-configuration magnet. Static and dynamic MR-defecography was performed using recognized parameters and well-established diagnostic criteria. Sixty-seven out of 105 (64 %) patients found the prone position more comfortable for the evacuation of rectal contrast while 10/105 (9.5 %) were unable to empty their rectum despite repeated attempts. Increased hiatus size, anterior rectocele and focal or extensive defects of the levator ani muscle were the most frequent abnormalities (67.6, 60.0 and 51.4 %, respectively). An MR-based classification was developed based on the combinations of abnormalities found: Grade 1 = functional abnormality, including paradoxical contraction of the puborectalis muscle, without anatomical defect affecting the musculo-fascial structures; Grade 2 = functional defect associated with a minor anatomical defect such as rectocele ≤ 2 cm in size and/or first-degree intussusception; Grade 3 = severe defects confined to the posterior anatomical compartment, including >2 cm rectocele, second- or higher-degree intussusception, full-thickness external rectal prolapse, poor mesorectal posterior fixation, rectal descent >5 cm, levator ani muscle rupture, ballooning of the levator hiatus and focal detachment of the endopelvic fascia; Grade 4 = combined defects of two or three pelvic floor compartments, including cystocele, hysterocele, enlarged urogenital

  20. Sportsmen's Groin-Diagnostic Approach and Treatment With the Minimal Repair Technique: A Single-Center Uncontrolled Clinical Review.

    Science.gov (United States)

    Muschaweck, Ulrike; Berger, Luise Masami

    2010-05-01

    Sportsmen's groin, also called sports hernia and Gilmore groin, is one of the most frequent sports injuries in athletes and may place an athletic career at risk. It presents with acute or chronic groin pain exacerbated with physical activity. So far, there is little consensus regarding pathogenesis, diagnostic criteria, or treatment. There have been various attempts to explain the cause of the groin pain. The assumption is that a circumscribed weakness in the posterior wall of the inguinal canal, which leads to a localized bulge, induces a compression of the genital branch of the genitofemoral nerve, considered responsible for the symptoms. The authors developed an innovative open suture repair-the Minimal Repair technique-to fit the needs of professional athletes. With this technique, the circumscribed weakness of the posterior wall of the inguinal canal is repaired by an elastic suture; the compression on the nerve is abolished, and the cause of the pain is removed. In contrast with that of common open suture repairs, the defect of the posterior wall is not enlarged, the suture is nearly tension free, and the patient can return to full training and athletic activity within a shorter time. The outcome of patients undergoing operations with the Minimal Repair technique was compared with that of commonly used surgical procedures. THE FOLLOWING ADVANTAGES OF THE MINIMAL REPAIR TECHNIQUE WERE FOUND: no insertion of prosthetic mesh, no general anesthesia required, less traumatization, and lower risk of severe complications with equal or even faster convalescence. In 2009, a prospective cohort of 129 patients resumed training in 7 days and experienced complete pain relief in an average of 14 days. Professional athletes (67%) returned to full activity in 14 days (median). The Minimal Repair technique is an effective and safe way to treat sportsmen's groin.

  1. A hybrid body technique: does the pulse diagnostic cun guan chi method have Chinese-Tibetan origins?

    Science.gov (United States)

    Hsu, Elisabeth

    2008-01-01

    This article investigates the medieval origins of the main pulse diagnostic method in contemporary Chinese medicine, sometimes known as san bu (three sectors) method, which requires physicians to examine the mai (vessels, vessel movements or pulse) on the wrist at the three locations cun guan chi (inch, gate, foot). The article provides evidence to suggest that this body technique grew out of an earlier Chinese one, the cun chi (inch-foot) method, which appears to have aimed at investigating the qualities of yin and yang in order to determine the condition of a patient by means of exploring fairly large areas of the patient's body surface with the palms. The article furthermore posits that the cun chi method was decisively transformed in medieval times, presumably due to the impact of early Tibetan pulse diagnostic practices: it became framed in a numerology of three and started advocating the use of the fingertips for sensing the pulse beats. The article, which draws on detailed textual analyses of medieval manuscripts, on visual evidence and also on psychophysical research, furthermore highlights how misunderstandings can constructively contribute to cultural communication.

  2. Laser diagnodent: a comparative study with other diagnostic techniques; Laser diagnodent: estudo comparativo com outras tecnicas de diagnostico

    Energy Technology Data Exchange (ETDEWEB)

    Godinho, Reugma Rego

    2002-07-01

    An evaluation of the Diagnodent equipment (Kavo Company, Germany) for the occlusal caries detection was dane through the comparison with other conventional diagnostic techniques, such as visual inspection, intra-oral micro camera and digital X-ray. The effectiveness of the equipment in the detection of hidden caries and its viability as a diagnosis method for caries in their initial stage was also studied. Fifty eight permanent molars and premolars teeth from patients with age between 6 and 30 years were studied. The obtained results indicated that the conventional methods employed for the caries diagnosis are unable to detect the carious lesion in its initial stage. The Diagnodent equipment has this capability to detect caries presenting a flawless surface, specially the hidden caries, allowing the dentist to decide between a preventive ar a conservative procedure. The main advantage of the Diagnodent is to be an objective method, compared to the visual and radiographic ones, that are dependent on the professional interpretation. The Diagnodent is, therefore, a promising alternative as an objective and standardized diagnosis method for the final diagnostic. (author)

  3. Diagnostic accuracy of magnetic resonance imaging techniques for treatment response evaluation in patients with head and neck tumors, a systematic review and meta-analysis

    NARCIS (Netherlands)

    van der Hoorn, Anouk; van Laar, Peter Jan; Holtman, Gea A.; Westerlaan, Henriette E.

    2017-01-01

    Background Novel advanced MRI techniques are investigated in patients treated for head and neck tumors as conventional anatomical MRI is unreliable to differentiate tumor from treatment related imaging changes. Purpose As the diagnostic accuracy of MRI techniques to detect tumor residual or

  4. Cardiovascular dysfunction in obesity and new diagnostic imaging techniques: the role of noninvasive image methods.

    Science.gov (United States)

    Barbosa, José Augusto A; Rodrigues, Alexandre B; Mota, Cleonice Carvalho C; Barbosa, Márcia M; Simões e Silva, Ana C

    2011-01-01

    Obesity is a major public health problem affecting adults and children in both developed and developing countries. This condition often leads to metabolic syndrome, which increases the risk of cardiovascular disease. A large number of studies have been carried out to understand the pathogenesis of cardiovascular dysfunction in obese patients. Endothelial dysfunction plays a key role in the progression of atherosclerosis and the development of coronary artery disease, hypertension and congestive heart failure. Noninvasive methods in the field of cardiovascular imaging, such as measuring intima-media thickness, flow-mediated dilatation, tissue Doppler, and strain, and strain rate, constitute new tools for the early detection of cardiac and vascular dysfunction. These techniques will certainly enable a better evaluation of initial cardiovascular injury and allow the correct, timely management of obese patients. The present review summarizes the main aspects of cardiovascular dysfunction in obesity and discusses the application of recent noninvasive imaging methods for the early detection of cardiovascular alterations.

  5. Diagnostic accuracy of dynamic contrast-enhanced MR imaging of renal masses with rapid-acquisition spin-echo technique

    International Nuclear Information System (INIS)

    Eilenberg, S.S.; Lee, J.K.T.; Brown, J.J.; Heiken, J.P.; Mirowitz, S.A.

    1990-01-01

    This paper compares the diagnostic accuracy of Gd-DTPA-enhanced rapid-acquisition spin-echo (RASE) imaging with standard spin-echo techniques for detecting renal cysts and solid renal neoplasms. RASE imaging combines a short TR (275 msec)/short TE (10 msec), single excitation pulse sequence with half-Fourier data sampling. Eighteen patients with CT evidence of renal masses were first evaluated with standard T1-and T2-weighted SE sequences. Pre- and serial postcontrast (Cd-DTPA, 0.1 mmol./kg) RASE sequences were then performed during suspended respiration. A final set of postcontrast images was obtained with the standard T1-weighted SE sequence. Each set of MR images was first reviewed separately (ie, T1, T2, pre- and post-contrast RASE, etc)

  6. Diagnostic value of renal clearance techniques using iodo-hippuran /sup 131/I and /sup 99m/-DTPA

    Energy Technology Data Exchange (ETDEWEB)

    Heidenreich, P; Hoer, G [Technische Univ. Muenchen (Germany, F.R.). Nuklearmedizinische Klinik und Poliklinik

    1976-01-01

    Methods and clinical indications of divided renal clearance determination using /sup 131/I-hippuran are presented and their value as a diagnostic tool in urology is shown by two case reports. For quantitative assessment of renal function we prefer the whole body clearance (with partial shielding of kidneys and bladder) which obviates the necessity of the theoretical assumption of compartmental distribution of radiopharmaceuticals. Using simplified clearance techniques only based on analysis of plasma disappearance curves (slope clearance one- and two-compartment model), clinically useful results are also obtainable, especially in follow up studies. The evaluation of tubular and glomerular kidney function by simultaneous application of /sup 131/I-hippuran and sup(99m)Tc-DTPA is suitable for estimation of filtration fraction in patients with urological and nephrological diseases. Even with regard to therapy and follow up studies of urinary tract tuberculosis, remarkable dignostic informations may be achieved.

  7. Modern endoscopic techniques of precancerous stomach conditions diagnostics: problems and possibilities

    Directory of Open Access Journals (Sweden)

    Yu.M. Stepanov

    2017-02-01

    (in the antrum, along the small curvature of the stomach diffusely. According to the researchers’ data, the presence of the intestinal metaplasia on the lesser curvature of the stomach has a strong association with cancer risk. The different kinds of endoscopic devices allow diagnostically diffentiate atrophy and intestinal metaplasia of the stomach. Endoscopy white light can’t reliably diagnose stomach precancerous changes, while videoendoscopy with magnifications and narrow band imaging (NBI, according to researchers’ data, significantly improves the diagnosis of this disease. The basis of diagnosis is increasing verification of two main structures: the architectonic subepithelial microvascular network microstructure and mucosal surface, which has a different pattern in the body and antral stomach. But to date there is no common classification of changes to these structures in various pathological changes. There are a large number of classifications of changes in endoscopy with NBI mode and optical zoom: Yagi (2002, M. Dinis-Ribeiro (2003, G.K. Anagnostopoulos et al. (2007, T. Tahara (2009, P. Pimentel-Nunes, M. Dinis-Ribeiro (2012. It is noted that the problem is that NBI with zoom is practically impossible to use in daily clinical practice, the method requires a certain level of knowledge and endoscope type, available only in several centers, as well as the use of sedation for maximum effective inspection.

  8. SU-F-T-427: Utilization and Evaluation of Diagnostic CT Imaging with MAR Technique for Radiation Therapy Treatment Planning

    International Nuclear Information System (INIS)

    Xu, M; Foster, R; Parks, H; Pankuch, M

    2016-01-01

    Purpose: The objective was to utilize and evaluate diagnostic CT-MAR technique for radiation therapy treatment planning. Methods: A Toshiba-diagnostic-CT acquisition with SEMAR(Single-energy-MAR)-algorism was performed to make the metal-artifact-reduction (MAR) for patient treatment planning. CT-imaging datasets with and without SEMAR were taken on a Catphan-phantom. Two sets of CT-numbers were calibrated with the relative electron densities (RED). A tissue characterization phantom with Gammex various simulating material rods was used to establish the relationship between known REDs and corresponding CT-numbers. A GE-CT-sim acquisition was taken on the Catphan for comparison. A patient with bilateral hip arthroplasty was scanned in the radiotherapy CT-sim and the diagnostic SEMAR-CT on a flat panel. The derived SEMAR images were used as a primary CT dataset to create contours for the target, critical-structures, and for planning. A deformable registration was performed with VelocityAI to track voxel changes between SEMAR and CT-sim images. The SEMAR-CT images with minimal artifacts and high quality of geometrical and spatial integrity were employed for a treatment plan. Treatment-plans were evaluated based on deformable registration of SEMAR-CT and CT-sim dataset with assigned CT-numbers in the metal artifact regions in Eclipse v11 TPS. Results: The RED and CT-number relationships were consistent for the datasets in CT-sim and CT’s with and without SEMAR. SEMAR datasets with high image quality were used for PTV and organ delineation in the treatment planning process. For dose distribution to the PTV through the DVH analysis, the plan using CT-sim with the assigned CT-number showed a good agreement to those on deformable CT-SEMAR. Conclusion: A diagnostic-CT with MAR-algorithm can be utilized for radiotherapy treatment planning with CT-number calibrated to the RED. Treatment planning comparison and DVH shows a good agreement in the PTV and critical organs between

  9. Cardiovascular dysfunction in obesity and new diagnostic imaging techniques: the role of noninvasive image methods

    Directory of Open Access Journals (Sweden)

    Barbosa JA

    2011-05-01

    Full Text Available José Augusto A Barbosa¹, Alexandre B Rodrigues¹, Cleonice Carvalho C Mota¹, Márcia M Barbosa², Ana C Simões e Silva¹¹Department of Pediatrics, Faculty of Medicine, Federal University of Minas Gerais (UFMG, Belo Horizonte, Minas Gerais, Brazil; ²Ecocenter, Socor Hospital, Belo Horizonte, Minas Gerais, BrazilAbstract: Obesity is a major public health problem affecting adults and children in both developed and developing countries. This condition often leads to metabolic syndrome, which increases the risk of cardiovascular disease. A large number of studies have been carried out to understand the pathogenesis of cardiovascular dysfunction in obese patients. Endothelial dysfunction plays a key role in the progression of atherosclerosis and the development of coronary artery disease, hypertension and congestive heart failure. Noninvasive methods in the field of cardiovascular imaging, such as measuring intima-media thickness, flow-mediated dilatation, tissue Doppler, and strain, and strain rate, constitute new tools for the early detection of cardiac and vascular dysfunction. These techniques will certainly enable a better evaluation of initial cardiovascular injury and allow the correct, timely management of obese patients. The present review summarizes the main aspects of cardiovascular dysfunction in obesity and discusses the application of recent noninvasive imaging methods for the early detection of cardiovascular alterations.Keywords: cardiovascular risk, endothelium dysfunction, obesity, strain and strain rate, tissue Doppler

  10. Foetal radiography for suspected skeletal dysplasia: technique, normal appearances, diagnostic approach

    Energy Technology Data Exchange (ETDEWEB)

    Calder, Alistair D. [Great Ormond Street Hospital for Children NHS Foundation Trust, Radiology Department, London (United Kingdom); Offiah, Amaka C. [Sheffield Children' s NHS Foundation Trust, Academic Unit of Child Health, Sheffield (United Kingdom)

    2015-04-01

    Despite advances in antenatal imaging and genetic techniques, post-delivery post-mortem foetal radiography remains the key investigation in accurate diagnosis of skeletal dysplasia manifesting in the foetus. Foetal radiography is best performed using pathology-specimen radiography equipment and is often carried out in the pathology department without involvement of the radiology unit. However, paediatric radiologists may be asked to interpret post-mortem foetal radiographs when an abnormality is suspected. Many foetal radiographs are carried out before 20 weeks' gestation, and the interpreting radiologist needs to be familiar with the range of normal post-mortem foetal appearances at different gestational ages, as well as the appearances of some of the more commonly presenting skeletal dysplasias, and will benefit from a systematic approach when assessing more challenging cases. In this pictorial essay, we illustrate various normal post-mortem foetal radiographic appearances, give examples of commonly occurring skeletal dysplasias, and describe an approach to establishing more difficult diagnoses. (orig.)

  11. A New Paradigm for Tissue Diagnostics: Tools and Techniques to Standardize Tissue Collection, Transport, and Fixation.

    Science.gov (United States)

    Bauer, Daniel R; Otter, Michael; Chafin, David R

    2018-01-01

    Studying and developing preanalytical tools and technologies for the purpose of obtaining high-quality samples for histological assays is a growing field. Currently, there does not exist a standard practice for collecting, fixing, and monitoring these precious samples. There has been some advancement in standardizing collection for the highest profile tumor types, such as breast, where HER2 testing drives therapeutic decisions. This review examines the area of tissue collection, transport, and monitoring of formalin diffusion and details a prototype system that could be used to help standardize tissue collection efforts. We have surveyed recent primary literature sources and conducted several site visits to understand the most error-prone processes in histology laboratories. This effort identified errors that resulted from sample collection techniques and subsequent transport delays from the operating room (OR) to the histology laboratories. We have therefore devised a prototype sample collection and transport concept. The system consists of a custom data logger and cold transport box and takes advantage of a novel cold + warm (named 2 + 2) fixation method. This review highlights the beneficial aspects of standardizing tissue collection, fixation, and monitoring. In addition, a prototype system is introduced that could help standardize these processes and is compatible with use directly in the OR and from remote sites.

  12. Foetal radiography for suspected skeletal dysplasia: technique, normal appearances, diagnostic approach

    International Nuclear Information System (INIS)

    Calder, Alistair D.; Offiah, Amaka C.

    2015-01-01

    Despite advances in antenatal imaging and genetic techniques, post-delivery post-mortem foetal radiography remains the key investigation in accurate diagnosis of skeletal dysplasia manifesting in the foetus. Foetal radiography is best performed using pathology-specimen radiography equipment and is often carried out in the pathology department without involvement of the radiology unit. However, paediatric radiologists may be asked to interpret post-mortem foetal radiographs when an abnormality is suspected. Many foetal radiographs are carried out before 20 weeks' gestation, and the interpreting radiologist needs to be familiar with the range of normal post-mortem foetal appearances at different gestational ages, as well as the appearances of some of the more commonly presenting skeletal dysplasias, and will benefit from a systematic approach when assessing more challenging cases. In this pictorial essay, we illustrate various normal post-mortem foetal radiographic appearances, give examples of commonly occurring skeletal dysplasias, and describe an approach to establishing more difficult diagnoses. (orig.)

  13. Diagnostic radiography students' perceptions of formative peer assessment within a radiographic technique module

    International Nuclear Information System (INIS)

    Elshami, W.; Abdalla, M.E.

    2017-01-01

    Introduction: Assessment is a central part of student learning. Student involvement in peer assessment leads to significant improvement in students' performance, supports students' learning, promotes the development of evaluation skills and encourages reflection. Aim: The aim of this study is to assess perceptions of the Formative Peer Assessment (FPA) initiative within a higher education setting for undergraduate radiography students. Methods: Qualitative action research was conducted. Students were allowed to anonymously assess each other's assignments using a standardized evaluation sheet that they had been trained to use. Participants' perceptions were assessed through focus group discussion. Results: The findings showed that students' experiences with peer assessment were positive. Students acknowledged that they received valuable feedback and learned from assessing their peers. Students recommended the need for training and suggested using more than one evaluator. Conclusion: The FPA initiative in the study institution believed to be succeed as the students had a positive experience with the FPA. Students learnt from PA and from self-assessment. Implementation of PA will promote reflection and critical thinking and problem solving skills, that are important traits in radiography graduate profile as in radiography clinical practice the professional require to modify imaging techniques and critique images to ensure the quality of care. - Highlights: • Participants had a positive experience with the Formative Peer Assessment (FPA). • Students believed that the FPA had a positive impact on their learning. • FPA was time-consuming but benefits outweigh the extra time commitment. • Comprehensive training and detailed grading rubric are recommended to improve FPA.

  14. The diagnostic value of double-contrast-technique cystography in the evaluation of benign and malignant lesions of the urinary bladder

    International Nuclear Information System (INIS)

    Beyer, D.; Koester, R.; Schuett, H.

    1979-01-01

    Cystography by double-contrast-technique as simple and quick method of evaluating benign and malignant lesions of the urinary bladder is being described. 301 examinations were reviewed and are being discussed in regard to diagnostic value, indication, complication and radiation exposure of this method. A few typical cases are being demonstrated to illustrate the value of this method in the spectrum of other diagnostic methods in the workup of urinary bladder lesions. (orig.) [de

  15. From a genetic innovation to mass health programmes: the diffusion of Down's Syndrome prenatal screening and diagnostic techniques in France.

    Science.gov (United States)

    Vassy, Carine

    2006-10-01

    Down's Syndrome prenatal diagnostic and screening techniques have spread widely in France over the last 30 years and are now part of the routine clinical practice of prenatal care. These techniques, which originated in the field of genetics, ultrasonography and biochemistry, were the first to provide the possibility of choosing the features of the foetus, or at least to reject some of its characteristics. They lead to new norms of healthy foetuses and a progressive acceptance of medical abortions. The aim of this paper is to understand how the use of these tests has been generalised in France despite scientific controversies about their risks and ethical questioning about a potential renewal of eugenics. It analyses the representations of public needs that have been articulated by key players in the scientific and medical fields. This research explores political and administrative decision making processes to understand how progressively widening public access to prenatal testing has been organised and funded. The results highlight the scientific and political role of biomedical researchers, the forms of involvement of health authorities and politicians, and the passive participation of the vast majority of the users. The paper also examines the characteristics of the French health system that facilitated the generalised use of the technology.

  16. The problem of sexual imbalance and techniques of the self in the Diagnostic and Statistical Manual of Mental Disorders.

    Science.gov (United States)

    Flore, Jacinthe

    2016-09-01

    This article examines the problematization of sexual appetite and its imbalances in the development of the Diagnostic and Statistical Manual of Mental Disorders (DSM) in the twentieth and twenty-first centuries. The dominant strands of historiographies of sexuality have focused on historicizing sexual object choice and understanding the emergence of sexual identities. This article emphasizes the need to contextualize these histories within a broader frame of historical interest in the problematization of sexual appetite. The first part highlights how sexual object choice, as a paradigm of sexual dysfunctions, progressively receded from medical interest in the twentieth century as the clinical gaze turned to the problem of sexual appetite and its imbalances. The second part uses the example of the newly introduced Female Sexual Interest/Arousal Disorder in the DSM-5 to explore how the Manual functions as a technique for taking care of the self. I argue that the design of the Manual and associated inventories and questionnaires paved the way for their interpretation and application as techniques for self-examination. © The Author(s) 2016.

  17. Evaluation of the Acridine Orange Fluorescence Technique and the Indirect Fluorescent Antibody as Diagnostic Tests for Tropical Theileriosis

    Directory of Open Access Journals (Sweden)

    Mahmoud

    2011-06-01

    Full Text Available This study was carried out to evaluate the use of acridine orange fluorescence technique on blood slides as a rapid diagnostic test for tropical theileriosis in comparison with the Giemsa-stained thin blood film technique. Also the indirect fluorescent antibody test has been employed for the serodiagnosis of tropical theileriosis. The study was carried out on 62 young and 48 adult Friesian cattle suffering from clinical tropical theileriosis in Qassim Region, Central Saudi Arabia, during the period from August 2006 to July 2008. For control, blood samples were also obtained from 25 young and 25 adult, clinically healthy, Friesian cattle, selected at random from different dairy farms in Qassim Region. Thin blood films were fixed with methanol and stained with Giemsa and acridine orange and were examined by two independent microbiologists. There was 100% correlation in the interpretation of slides stained with Giemsa and acridine orange both with respect to positivity and negativity, between the two microbiologists. It is concluded that if facilities are available acridine orange is a valuable alternative for screening tropical theileriosis. The method may also have potential value in the diagnosis of Theileria parva, which causes East Coast fever, and also other Theileria species. Results of the present study also showed that IFA test was not found sufficiently sensitive and specific as has been reported earlier. [Vet. World 2011; 4(8.000: 341-344

  18. In-cylinder pressure-based direct techniques and time frequency analysis for combustion diagnostics in IC engines

    International Nuclear Information System (INIS)

    D’Ambrosio, S.; Ferrari, A.; Galleani, L.

    2015-01-01

    Highlights: • Direct pressure-based techniques have been applied successfully to spark-ignition engines. • The burned mass fraction of pressure-based techniques has been compared with that of 2- and 3-zone combustion models. • The time frequency analysis has been employed to simulate complex diesel combustion events. - Abstract: In-cylinder pressure measurement and analysis has historically been a key tool for off-line combustion diagnosis in internal combustion engines, but online applications for real-time condition monitoring and combustion management have recently become popular. The present investigation presents and compares different low computing-cost in-cylinder pressure based methods for the analyses of the main features of combustion, that is, the start of combustion, the end of combustion and the crankshaft angle that responds to half of the overall burned mass. The instantaneous pressure in the combustion chamber has been used as an input datum for the described analytical procedures and it has been measured by means of a standard piezoelectric transducer. Traditional pressure-based techniques have been shown to be able to predict the burned mass fraction time history more accurately in spark ignition engines than in diesel engines. The most suitable pressure-based techniques for both spark ignition and compression ignition engines have been chosen on the basis of the available experimental data. Time–frequency analysis has also been applied to the analysis of diesel combustion, which is richer in events than spark ignited combustion. Time frequency algorithms for the calculation of the mean instantaneous frequency are computationally efficient, allow the main events of the diesel combustion to be identified and provide the greatest benefits in the presence of multiple injection events. These algorithms can be optimized and applied to onboard diagnostics tools designed for real control, but can also be used as an advanced validation tool for

  19. Diagnostic techniques for viroids

    Czech Academy of Sciences Publication Activity Database

    Gucek, T.; Trdan, S.; Jakše, J.; Javornik, B.; Matoušek, Jaroslav; Radisek, S.

    2017-01-01

    Roč. 66, č. 3 (2017), s. 339-358 ISSN 0032-0862 Institutional support: RVO:60077344 Keywords : potato-spindle-tuber * multiplex rt-pcr * mediated isothermal amplification Subject RIV: EE - Microbiology, Virology OBOR OECD: Biochemistry and molecular biology Impact factor: 2.425, year: 2016

  20. Comparison of four diagnostic techniques for detection of Trichomonas vaginalis infection in females attending tertiary care hospital of North India

    Directory of Open Access Journals (Sweden)

    Razia Khatoon

    2015-01-01

    Full Text Available Background: Trichomonas vaginalis causes a common sexually transmitted disease trichomoniasis, which may lead to increased risk of transmission of human immunodeficiency virus infection and other pelvic inflammatory diseases. Wet mount examination is the most common test for diagnosis, but it has low sensitivity. Acridine orange staining can be used for diagnosis, but it requires special microscopic facility. Culture is considered as the gold standard, but it takes a long time for diagnosis. OSOM Trichomonas Rapid Test is a recently introduced rapid method based on immunochromatographic assay of trichomonal protein antigens. Hence, the present study was done to compare these four diagnostic techniques for detection of trichomoniasis in females with vaginal discharge. Materials and Methods: Vaginal swabs were taken from 835 female patients and wet mount examination, acridine orange staining, culture in Kupferberg medium, and OSOM Trichomonas Rapid Test, were performed. Results: Out of 835 patients included in our study, 68 (8.1% positive cases of trichomoniasis were detected by culture. OSOM Trichomonas Rapid Test detected 63 (7.5% cases, acridine orange staining detected 53 (6.3% cases, whereas, wet mount examination detected only 45 (5.4% positive cases. OSOM Trichomonas Rapid Test performed well and showed high sensitivity and specificity of 88.2% and 99.6%, respectively. Conclusion: As OSOM Trichomonas Rapid Test is a point of care test and gave better results than both wet mount examination and acridine orange staining; it can be used as a routine test in peripheral areas lacking laboratory facilities.

  1. Diagnostic techniques for measuring temperature transients and stress transients in the first wall of an ICF reactor

    International Nuclear Information System (INIS)

    Melamed, N.T.; Taylor, L.H.

    1983-01-01

    The primary challenge in the design of an Inertial Confinement Fusion (ICF) power reactor is to make the first wall survive the frequent explosions of the pellets. Westinghouse has proposed a dry wall design consisting of steel tubes coated with tantalum. This report describes the design of a test chamber and two diagnostic procedures for experimentally determining the reliability of the Westinghouse design. The test chamber simulates the x-ray and ion pulse irradiation of the wall due to a pellet explosion. The diagnostics consist of remote temperature sensing and surface deformation measurements. The chamber and diagnostics can also be used to test other first-wall designs

  2. Recent developments in diagnostic imaging techniques and management for acute pulmonary embolism. Multicenter registry by the Japanese Society of Pulmonary Embolism Research

    International Nuclear Information System (INIS)

    Sakuma, Masahito; Okada, Osamu; Nakamura, Mashio

    2003-01-01

    There are many reports on the diagnosis and management of acute pulmonary embolism (APE), but there have been no investigations concerning the actual conditions in which recent developments in diagnostic imaging techniques and therapies have been applied in clinical practice. The present study was designed to investigate the changes in diagnostic imaging techniques and therapies for APE. Three hundred and nine APE patients diagnosed during January 1994-October 1997 (Group 1) were compared with 257 APE patients diagnosed during November 1997-October 2000 (Group 2) in terms of the diagnostic imaging techniques and therapies for APE. Compared with Group 1, pulmonary angiography and contrast-enhanced computed tomography were more frequently performed for diagnosis in Group 2 [45.3% vs 56.8% (p=0.0069) and 13.9% vs 57.6% (p<0.0001), respectively]. Heparin and vena cava filter were used more often in Group 2 [74.4% vs 82.1% (p=0.033) and 18.4% vs 33.9% (p<0.0001), respectively]. The frequency of thrombolytic therapy was unchanged between the two groups. Warfarin use in discharged patients increased from 71.9% to 83.8% (p=0.0022). However, the examination rates for deep vein thrombosis (DVT) were low (60.8% in Group 1 and 65.4% in Group 2, p=0.29) and unchanged using any imaging techniques. The diagnostic imaging techniques for APE increased in variety and the management has improved, while the diagnosis for DVT remains unchanged. (author)

  3. Effects of optical diagnostic techniques on the accuracy of laminar flame speeds measured from Bunsen flames: OH* chemiluminescence, OH-PLIF and acetone/kerosene-PLIF

    Science.gov (United States)

    Wu, Yi; Modica, Vincent; Yu, Xilong; Li, Fei; Grisch, Frédéric

    2018-01-01

    The effects of optical diagnostic techniques on the accuracy of laminar flame speed measured from Bunsen flames were investigated. Laminar flame speed measurements were conducted for different fuel/air mixtures including CH4/air, acetone/air and kerosene (Jet A-1)/air in applying different optical diagnostic techniques, i.e. OH* chemiluminescence, OH-PLIF and acetone/kerosene-PLIF. It is found that the OH* chemiluminescence imaging technique cannot directly derive the location of the outer edge of the fresh gases and it is necessary to correct the position of the OH* peak to guarantee the accuracy of the measurements. OH-PLIF and acetone/kerosene-PLIF respectively are able to measure the disappearance of the fresh gas contour and the appearance of the reaction zone. It shows that the aromatic-PLIF technique gives similar laminar flame speed values when compared with those obtained from corrected OH* chemiluminescence images. However, discrepancies were observed between the OH-PLIF and the aromatic-PLIF techniques, in that OH-PLIF slightly underestimates laminar flame speeds by up to 5%. The difference between the flame contours obtained from different optical techniques are further analysed and illustrated with 1D flame structure simulation using detailed kinetic mechanisms.

  4. A general purpose diagnostic technique for marine diesel engines - Application on the main propulsion and auxiliary diesel units of a marine vessel

    International Nuclear Information System (INIS)

    Lamaris, V.T.; Hountalas, D.T.

    2010-01-01

    Diesel engines are widely used in marine applications (i.e. propulsion and auxiliaries) except from a few cases where gas or steam turbines are used. This is the result of their high efficiency, power concentration and reliability compared to other compatible or alternative power sources. The proper and efficient operation of the engines (main engine and diesel generator units) in marine applications is critical, and therefore techniques or systems that determine engine current condition and detect potential faults are extremely important. Furthermore, it is advantageous when such techniques can be applied on different engine configurations and provide reliable results, because on a vessel usually exist diesel engines of different type, i.e. the main propulsion unit is a large low-speed two-stroke diesel engine while the diesel generators are four-stroke medium or high speed engines. In the present work is described and evaluated for the first time the application of an improved diagnostic technique, developed by the authors, on both the main engine and the auxiliary units of a commercial marine vessel. The diagnostic technique is based on a thermodynamic simulation model. The simulation model embedded in the technique has been modified, namely an existing two-zone model is replaced by a multi-zone one. With this modification it is avoided model constant tuning with the operating conditions. This is extremely important for the diagnostic philosophy of the proposed technique. Using data from engine shop tests, the simulation model is calibrated (i.e. model constants are determined) and the engine reference condition is obtained. The simulation model is then used to estimate the current engine condition, using field measurements (i.e. cylinder pressure measurements, periphery data, etc.). From the results it is revealed that the diagnosis method provides detailed information for the operating condition of both engines and the values of parameters that cannot be

  5. The detection of lumpy skin disease virus in samples of experimentally infected cattle using different diagnostic techniques

    Directory of Open Access Journals (Sweden)

    E.S.M. Tuppurainen

    2005-09-01

    Full Text Available Lumpy skin disease (LSD is a disease of cattle, primarily in Africa and Madagascar and rarely in the Middle East. It is caused by a capripoxvirus that belongs to the family Poxviridae. The disease is of economic importance in endemic areas. Effective control of LSD requires accurate and rapid laboratory techniques to confirm a tentative clinical diagnosis. Comparative studies on different diagnostic tests used at different stages of the disease have not been done. The aim of this study was to compare several of these tests. Six seronegative bulls, between 11 and 20 months of age, were infected intravenously and kept in an insect-free facility. The course of the infection was monitored. During a 3-month period blood samples and skin biopsies were collected for virus isolation and polymerase chain reaction (PCR. Skin biopsies were also examined using transmission electron microscopy (TEM. The incubation period in infected animals varied from 4-5 days. The length of the viraemic period did not correlate with the severity of clinical disease. Viraemia was detected from 1-12 days using virus isolation and from 4-11 days using the PCR, which is longer than has previously been reported. Virus was isolated from skin biopsies until Day 39 post infection (p.i. and PCR could demonstrate viral DNA until Day 92 p.i. Transmission electron microscopy of negatively stained skin biopsies detected LSD virus only in one of the four bulls that developed skin lesions until Day 33 p.i. The PCR was a fast and sensitive method to demonstrate viral DNA in blood and skin samples. It could detect viral nucleic acid in skin lesions 53 days longer than virus isolation. Virus isolation from blood and skin samples was sensitive and reliable, but as a single test it may be too time-consuming to use although this depends on how rapidly the diagnosis must be confirmed. In conclusion, this study showed the PCR to be superior in detecting LSD virus from blood and skin samples

  6. Use of RT-PCR and elisa techniques for the diagnostic of infectious bronchitis virus in broilers at slaughter

    Directory of Open Access Journals (Sweden)

    Davi de Oliveira Almeida

    2015-03-01

    Full Text Available ABSTRACT. Almeida D.O., Tortely R., Nascimento E.R., Khan M., Pereira V.L.A & Babapoor S. [Use of RT-PCR and elisa techniques for the diagnostic of infectious bronchitis virus in broilers at slaughter.] Uso das técnicas de RT-PCR e elisa no diagnóstico da bronquite infecciosa em frangos de corte ao abate. Revista Brasileira de Medicina Veterinária, 37(1:55-59, 2015. Departamento de Saúde Coletiva Veterinária e Saúde Pública, Universidade Federal Fluminense, Rua Vital Brazil Filho, 64, Santa Rosa, Niterói, RJ 24230-340, Brasil. E-mail: elmiro@vm.uff.br Avian infectious bronchitis (IB is a viral, acute and highly contagious disease caused by infectious bronchitis virus (IBV. The disease affects broilers improvement and performance causing major economic losses in the world poultry industry. Generally, IBV infections can be diagnosed by detection of IBV itself or the specific antibody response. This study aimed to detect IBV in broilers under Sanitary Inspection by RT-PCR and ELISA, comparing the results and relating them with the average weight of the flock. Samples were collected from 40 vaccinated broiler flocks under Sanitary Inspection at slaughter. Ten birds from every flock were randomly selected and blood samples were collected for ELISA as well three birds had their trachea and caecal tonsils collected for RT- -PCR test. From 40 flocks, 30 were IBV positive by ELISA and 26 by RT-PCR, in which 15 were detected simultaneously in trachea and caecal tonsil and 5 in each sample. There was no agreement between ELISA and RT-PCR results regarding IBV diagnosis as well positivity in both tests was not statistically significant with the average weight of the flock. There was an improvement on IBV diagnosis when caecal tonsils and tracheas were used instead of just one of them. Considering the only vaccine serotype allowed by Brazilian government is the Mass serotype and its persistence in broilers would only be detected up to 28 days

  7. Diagnostic performance of state-of-the-art imaging techniques for morphological assessment of vascular abnormalities in patients with chronic thromboembolic pulmonary hypertension (CTEPH)

    Energy Technology Data Exchange (ETDEWEB)

    Ley, Sebastian [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg (Germany); Ley-Zaporozhan, Julia [University Hospital Heidelberg, Department of Diagnostic and Interventional Radiology, Heidelberg (Germany); Johannes Gutenberg University, Department of Diagnostic and Interventional Radiology; Universitaetsmedizin, Mainz (Germany); Pitton, Michael B.; Schneider, Jens; Wirth, Gesine M.; Dueber, Christoph; Kreitner, Karl-Friedrich [Johannes Gutenberg University, Department of Diagnostic and Interventional Radiology; Universitaetsmedizin, Mainz (Germany); Mayer, Eckhard [Kerckhoff-Hospital Bad Nauheim, Department of Thoracic Surgery, Bad Nauheim (Germany)

    2012-03-15

    To determine the most comprehensive imaging technique for the assessment of pulmonary arteries in patients with chronic thromboembolic pulmonary hypertension (CTEPH). 24 patients with CTEPH were examined by ECG-gated multi-detector CT angiography (MD-CTA), contrast-enhanced MR angiography (ce-MRA) and selective digital subtraction angiography (DSA) within 3 days. Two readers in consensus separately evaluated each imaging technique (48 main, 144 lobar and 449 segmental arteries) for typical changes like complete obstructions, vessel cut-offs, intimal irregularities, incorporated thrombus formations, and bands and webs. A joint interpretation of all three techniques served as a reference standard. Based on image quality, there was no non-diagnostic examination by either imaging technique. DSA did not sufficiently display 1 main, 3 lobar and 4 segmental arteries. The pulmonary trunk was not assessable by DSA. One patient showed thrombotic material at this level only by MD-CTA and MRA. Sensitivity and specificity of MD-CTA regarding CTEPH-related changes at the main/lobar and at the segmental levels were 100%/100% and 100%/99%, of ce-MRA 83.1%/98.6% and 87.7%/98.1%, and of DSA 65.7%/100% and 75.8%/100%, respectively. ECG-gated MD-CTA proved the most adequate technique for assessment of the pulmonary arteries in the diagnostic work-up of CTEPH patients. (orig.)

  8. Optimized design of shields for diagnostic X rays with NCRP 147 technique; Diseno optimizado de blindajes para rayos X diagnostico con tecnica NCRP 147

    Energy Technology Data Exchange (ETDEWEB)

    Gama T, G. [Calidad XXI SA de CV, Zacatecas 67-007 Col. Roma, 06700 Mexico D.F. (Mexico)]. e-mail: cxxi@prodigy.net.mx

    2006-07-01

    A comparison among the design techniques of shielding for X-ray diagnostic rooms with the NCRP 49 (1976) report technique, AAPM 39 (1993) Y the one of the NCRP 147 (2005) technique. The designs correspond to a room of conventional X-rays, one of fluoroscopy, one of tomography Y one of mammography. In all the cases it demonstrates that the NCRP 49 technique overestimate the shieldings. The causes of the overestimation of the NCRP 49 can be attributed to: a) high values of the work charge that don't consider the spectral fluence of the photons that are present in each room, b) to the differences in the values of the kerma in air without attenuation for the dispersed primary radiation Y of leakage among both reports. (Author)

  9. Myocardial tagging with steady state free precession techniques and semi-automatic postprocessing--impact on diagnostic value

    DEFF Research Database (Denmark)

    Johnson, Thorsten R C; Bayrhof, Nicole; Huber, Armin

    2007-01-01

    Our aim was to determine the diagnostic value of myocardial tagging sequences with regard to the evaluable share of the cardiac cycle. Thirty-three patients were examined at 1.5 T using tagging sequences with gradient-echo (GRE) readout, 18 patients at 1.5 T with steady-state free precession (SSF...

  10. A pilot study using laser-based technique for non-invasive diagnostics of hypertensive conditions in mice

    Science.gov (United States)

    Litvinova, Karina S.; Ahmad, Shakil; Wang, Keqing; Rafailov, Ilya E.; Sokolovski, Sergei G.; Zhang, Lin; Rafailov, Edik U.; Ahmed, Asif

    2016-02-01

    Endothelial dysfunction is directly linked to preeclampsia, a maternal hypertensive condition that is life threating for both the mother and the baby. Epidemiological studies show that women with a history of pre-eclampsia have an elevated risk for cardiovascular disease. Here we report a new non-invasive diagnostic test for preeclampsia in mice that allows us to non-invasively assess the condition of the animals during the experiment and treatment in established models of preeclampsia. A laser-based multifunctional diagnostics system (LAKK-M) was chosen to carry out non-invasive analysis of multiple parameters. The device was used to simultaneously record the microcirculatory blood flow and oxygen saturation, as well as fluorescence levels of endogenous fluorophores. Preliminary experiments were conducted on adenoviral (Ad-)- mediated overexpression of sFlt-1 (Ad-sFlt-1) to mimic preeclampsialike symptoms in mice. The recorded data displayed the ability of the LAKK-M diagnostics device to detect significant differences in perfusion measurements between the control and Ad-sFlt-1 treatment. Preliminary results provide a potential avenue to employ these diagnostics technology to monitor and aid in maintaining control of live animal conditions throughout the experiment and treatment.

  11. Value of five noninvasive diagnostic techniques and their combinations in diagnosis of liver fibrosis in patients with chronic hepatitis B

    Directory of Open Access Journals (Sweden)

    ZHANG Xu

    2016-10-01

    Full Text Available Objective To investigate the correlation of aspartate aminotransferase to platelet ratio index (APRI, FIB-4, Forns index, S index, and FibroScan with the degree of liver fibrosis, the diagnostic value of these techniques used alone or in combination, and the clinical value of these noninvasive techniques in the assessment of the degree of liver fibrosis in patients with chronic hepatitis B (CHB. Methods A retrospective analysis was performed for the clinical data of 91 patients with pathologically confirmed CHB who visited General Hospital of Ningxia Medical University and underwent liver biopsy from January 2009 to April 2015. According to the Scheuer pathological stage and liver fibrosis stage (S, the patients were divided into non-liver fibrosis group (a liver fibrosis stage of S0, 32 patients, mild liver fibrosis group (a liver fibrosis stage of <S2, 30 patients, and marked liver fibrosis group (a liver fibrosis stage of ≥S2, 29 patients. The APRI, FIB-4, Forns index, and S index were calculated, and liver stiffness was measured by FibroScan. An analysis of variance was used for the comparison of normally distributed continuous data between three groups, and the Dunnett t-test was used for further comparison between any two groups. The Spearman correlation analysis was also performed. Sensitivity, specificity, and area under the receiver operating characteristic curve (AUC were used to evaluate the value of these noninvasive techniques in the diagnosis of liver fibrosis. Results There were significant differences in age, albumin, aspartate aminotransferase, alanine aminotransferase, and platelet count between the three groups (F=3.552, 4.035, 4.374, and 5.992, all P<0.05, and there were significant differences in these parameters between the non-liver fibrosis group and the mild and marked liver fibrosis groups (P<0.05. There were significant differences in APRI, FIB-4, Forns index, S index, and FibroScan between the three groups (F

  12. Comparison of exercise perfusion and ventricular function imaging: an analysis of factors affecting the diagnostic accuracy of each technique

    International Nuclear Information System (INIS)

    Osbakken, M.D.; Okada, R.D.; Boucher, C.A.; Strauss, H.W.; Pohost, G.M.

    1984-01-01

    Exercise thallium-201 perfusion scans and gated equilibrium blood pool scans were performed in 120 catheterized patients with a chest pain syndrome. Eighty-six patients had coronary artery disease and 34 patients did not. The effects of gender, propranolol, exercise level, exercise ischemia, history of typical angina, history of previous myocardial infarction, electrocardiographic Q waves, number of diseases vessels and extent of coronary artery obstruction on diagnostic accuracy were evaluated. Thallium scans and anginal history were less sensitive for detecting coronary disease in women (men: thallium 79%; angina 77%; women: 54 and 46%, respectively; p less than 0.05). Exercise level did not significantly affect the diagnostic accuracy of either scan. Thallium and gated scans were both highly sensitive (95%) in detecting disease in 20 patients with a prior myocardial infarction, angina and a positive electrocardiogram. The sensitivity of the thallium scan significantly decreased as the number of diseased vessels decreased. Both thallium and gated scans were less frequently positive in patients with atypical angina or no Q waves, but were not significantly influenced by electrocardiographic ischemia. The sensitivity and specificity of both scans were low in 57 patients with the combination of atypical angina, no history of infarction and equivocal stress electrocardiogram thallium. When stress thallium scan evaluation included the electrocardiogram and thallium scan interpretation, the diagnostic accuracy was 81%. When all the information from gated scans (wall motion, ejection fraction, pulmonary blood volume) was combined for final gated scan evaluation, the diagnostic accuracy was 83%. When electrocardiographic data were added to all three gated scan variables, diagnostic accuracy was 77%

  13. Modeling and diagnostic techniques applicable to the analysis of pressure noise in pressurized water reactors and pressure-sensing systems

    International Nuclear Information System (INIS)

    Mullens, J.A.; Thie, J.A.

    1984-01-01

    Pressure noise data from a PWR are interpreted by means of a computer-implemented model. The model's parameters, namely hydraulic impedances and noise sources, are either calculated or deduced from fits to data. Its accuracy is encouraging and raises the possibility of diagnostic assistance for nuclear plant monitoring. A number of specific applications of pressure noise in the primary system of a PWR and in a pressure sensing system are suggested

  14. Application of the denaturing gradient gel electrophoresis (DGGE) technique as an efficient diagnostic tool for ciliate communities in soil

    OpenAIRE

    Jousset, Alexandre; Lara, Enrique; Nikolausz, Marcell; Harms, Hauke; Chatzinotasa, Antonis

    2010-01-01

    Ciliates (or Ciliophora) are ubiquitous organisms which can be widely used as bioindicators in ecosystems exposed to anthropogenic and industrial influences. The evaluation of the environmental impact on soil ciliate communities with methods relying on morphology-based identification may be hampered by the large number of samples usually required for a statistically supported, reliable conclusion. Cultivation-independent molecular-biological diagnostic tools are a promising alternative to gre...

  15. Complex polarimetric and spectral techniques in diagnostics of blood plasma of patients with ovarian cancer as a preliminary stage molecular genetic screening

    Science.gov (United States)

    Grzegorzewski, B.; Peresunko, O. P.; Yermolenko, S. B.

    2018-01-01

    This work is devoted to the substantiation and selection of patients with ovarian cancer (OC) for the purpose of conducting expensive molecular genetic studies on genotyping. As diagnostic methods have been used ultraviolet spectrometry samples of blood plasma in the liquid state, infrared spectroscopy middle range (2,5 - 25 microns) dry residue of plasma polarization and laser diagnostic technique of thin histological sections of biological tissues. Obtained results showed that the use of spectrophotometry in the range of 1000-3000 cm-1 allowed to establish quantitative parameters of the plasma absorption rate of blood of patients in the third group in different ranges, which would allow in the future to conduct an express analysis of the patient's condition (procedure screening) for further molecular-genetic typing on BRCA I and II.

  16. Comparison of the Diagnostic Performance of Power Doppler Ultrasound and a New Microvascular Doppler Ultrasound Technique (AngioPLUS) for Differentiating Benign and Malignant Breast Masses.

    Science.gov (United States)

    Jung, Hae Kyoung; Park, Ah Young; Ko, Kyung Hee; Koh, Jieun

    2018-03-12

    This study was performed to compare the diagnostic performance of power Doppler ultrasound (US) and a new microvascular Doppler US technique (AngioPLUS; SuperSonic Imagine, Aix-en-Provence, France) for differentiating benign and malignant breast masses. Power Doppler US and AngioPLUS findings were available in 124 breast masses with confirmed pathologic results (benign, 80 [64.5%]; malignant, 44 [35.5%]). The diagnostic performance of each tool was calculated to distinguish benign from malignant masses using a receiver operating characteristic curve analysis and compared. The area under the curve showed that AngioPLUS was superior to power Doppler US in differentiating benign from malignant breast masses, but the difference was not statistically significant. © 2018 by the American Institute of Ultrasound in Medicine.

  17. Reliability of diagnostic imaging techniques in suspected acute appendicitis: proposed diagnostic protocol; Indicacion de las tecnicas de diagnostico por la imagen en la sospecha de apendicitis aguda: propuesta de protocolo diagnostico

    Energy Technology Data Exchange (ETDEWEB)

    Cura del, J. L.; Oleaga, L.; Grande, D.; Vela, A. C.; Ibanez, A. M. [Hospital de Basureto. Bilbao (Spain)

    2001-07-01

    To study the utility of ultrasound and computed tomography (CT) in case of suspected appendicitis. To determine the diagnostic yield in terms of different clinical contexts and patient characteristics. to assess the costs and benefits of introducing these techniques and propose a protocol for their use. Negative appendectomies, complications and length of hospital stay in a group of 152 patients with suspected appendicitis who underwent ultrasound and CT were compared with those of 180 patients who underwent appendectomy during the same time period, but had not been selected for the first group: these patients costs for each group were calculated. In the first group, the diagnostic value of the clinical signs was also evaluated. The reliability of the clinical signs was limited, while the results with ultrasound and CT were excellent. The incidence of negative appendectomy was 9.6% in the study group and 12.2% in the control group. Moreover, there were fewer complications and a shorter hospital stay in the first group. Among men, however, the rate of negative appendectomy was lower in the control group. The cost of using ultrasound and CT in the management of appendicitis was only slightly higher than that of the control group. Although ultrasound and CT are not necessary in cases in which the probability of appendicitis is low or in men presenting clear clinical evidence, the use of these techniques is indicated in the remaining cases in which appendicitis is suspected. In children, ultrasound is the technique of choice. In all other patients, if negative results are obtained with one of the two techniques, the other should be performed. (Author) 49 refs.

  18. Diagnostic Accuracy of Imaging Modalities and Injection Techniques for the Diagnosis of Femoroacetabular Impingement/Labral Tear: A Systematic Review With Meta-analysis.

    Science.gov (United States)

    Reiman, Michael P; Thorborg, Kristian; Goode, Adam P; Cook, Chad E; Weir, Adam; Hölmich, Per

    2017-09-01

    Diagnosing femoroacetabular impingement/acetabular labral tear (FAI/ALT) and subsequently making a decision regarding surgery are based primarily on diagnostic imaging and intra-articular hip joint injection techniques of unknown accuracy. Summarize and evaluate the diagnostic accuracy and clinical utility of various imaging modalities and injection techniques relevant to hip FAI/ALT. Systematic review with meta-analysis. A computer-assisted literature search was conducted of MEDLINE, CINAHL, and EMBASE databases using keywords related to diagnostic accuracy of hip joint pathologic changes. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines were used for the search and reporting phases of the study. Quality assessment of bias and applicability was conducted using the Quality of Diagnostic Accuracy Studies (QUADAS) tool. Random effects models were used to summarize sensitivities (SN), specificities (SP), likelihood ratios (+LR and -LR), diagnostic odds ratios (DOR), and respective confidence intervals (CI). The search strategy and assessment for risk of bias revealed 25 articles scoring above 10/14 on the items of the QUADAS. Four studies investigated FAI, and the data were not pooled. Twenty articles on ALT qualified for meta-analysis. Pretest probability of ALT in the studies in this review was 81% (72%-88%), while the pretest probability of FAI diagnosis was 74% (95% CI, 51%-91%). The meta-analysis showed that computed tomography arthrography (CTA) demonstrated the strongest overall diagnostic accuracy: pooled SN 0.91 (95% CI, 0.83-0.96); SP 0.89 (95% CI, 0.74-0.97); +LR 6.28 (95% CI, 2.78-14.21); -LR 0.11 (95% CI, 0.06-0.21); and DOR 64.38 (95% CI, 19.17-216.21). High pretest probability of disease was demonstrated. Positive imaging findings increased the probability that a labral tear existed by a minimal to small degree with the use of magnetic resonance imaging/magnetic resonance angiogram (MRI/MRA) and ultrasound (US

  19. Advantages of the first-derivative probe technique over the three- and four-parameter probe techniques in fusion plasmas diagnostics

    Czech Academy of Sciences Publication Activity Database

    Hasan, E.; Dimitrova, Miglena; Popov, T.; Ivanova, P.; Dejarnac, Renaud; Stöckel, Jan; Pánek, Radomír

    2018-01-01

    Roč. 13, č. 4 (2018), č. článku P04005. ISSN 1748-0221 R&D Projects: GA MŠk(CZ) LM2015045 Institutional support: RVO:61389021 Keywords : Plasma potential * electron temperature * bi-Maxwellian EEDF * Divertor Langmuir probes * three- and four-parameter probe techniques * first-derivative probe technique Subject RIV: BL - Plasma and Gas Discharge Physics OBOR OECD: 2.11 Other engineering and technologies Impact factor: 1.220, year: 2016 http://iopscience.iop.org/article/10.1088/1748-0221/13/04/P04005/meta

  20. Facilities and techniques for x-ray diagnostic calibration in the 100-eV to 100-keV energy range

    International Nuclear Information System (INIS)

    Gaines, J.L.; Wittmayer, F.J.

    1986-01-01

    The Lawrence Livermore National Laboratory (LLNL) has been a pioneer in the field of x-ray diagnostic calibration for more than 20 years. The authors built steady state x-ray sources capable of supplying fluorescent lines of high spectral purity in the 100-eV to 100-keV energy range, and these sources have been used in the calibration of x-ray detectors, mirrors, crystals, filters, and film. This paper discusses their calibration philosophy and techniques, and describes some of the x-ray sources. Examples of actual calibration data are presented as well

  1. Facilities and Techniques for X-Ray Diagnostic Calibration in the 100-eV to 100-keV Energy Range

    Science.gov (United States)

    Gaines, J. L.; Wittmayer, F. J.

    1986-08-01

    The Lawrence Livermore National Laboratory (LLNL) has been a pioneer in the field of x-ray diagnostic calibration for more than 20 years. We have built steady state x-ray sources capable of supplying fluorescent lines of high spectral purity in the 100-eV to 100-keV energy range, and these sources have been used in the calibration of x-ray detectors, mirrors, crystals, filters, and film. This paper discusses our calibration philosophy and techniques, and describes some of our x-ray sources. Examples of actual calibration data are presented as well.

  2. Facilities and techniques for x-ray diagnostic calibration in the 100-eV to 100-keV energy range

    International Nuclear Information System (INIS)

    Gaines, J.L.; Wittmayer, F.J.

    1986-06-01

    The Lawrence Livermore National Laboratory (LLNL) has been a pioneer in the field of x-ray diagnostic calibration for more than 20 years. We have built steady state x-ray sources capable of supplying fluorescent lines of high spectral purity in the 100-eV to 100-keV energy range, and these sources have been used in the calibration of x-ray detectors, mirrors, crystals, filters, and film. This paper discusses our calibration philosophy and techniques, and describes some of our x-ray sources. Examples of actual calibration data are presented as well

  3. Application of the denaturing gradient gel electrophoresis (DGGE) technique as an efficient diagnostic tool for ciliate communities in soil.

    Science.gov (United States)

    Jousset, Alexandre; Lara, Enrique; Nikolausz, Marcell; Harms, Hauke; Chatzinotas, Antonis

    2010-02-01

    Ciliates (or Ciliophora) are ubiquitous organisms which can be widely used as bioindicators in ecosystems exposed to anthropogenic and industrial influences. The evaluation of the environmental impact on soil ciliate communities with methods relying on morphology-based identification may be hampered by the large number of samples usually required for a statistically supported, reliable conclusion. Cultivation-independent molecular-biological diagnostic tools are a promising alternative to greatly simplify and accelerate such studies. In this present work a ciliate-specific fingerprint method based on the amplification of a phylogenetic marker gene (i.e. the 18S ribosomal RNA gene) with subsequent analysis by denaturing gradient gel electrophoresis (DGGE) was developed and used to monitor community shifts in a polycyclic aromatic hydrocarbon (PAH) polluted soil. The semi-nested approach generated ciliate-specific amplification products from all soil samples and allowed to distinguish community profiles from a PAH-polluted and a non-polluted control soil. Subsequent sequence analysis of excised bands provided evidence that polluted soil samples are dominated by organisms belonging to the class Colpodea. The general DGGE approach presented in this study might thus in principle serve as a fast and reproducible diagnostic tool, complementing and facilitating future ecological and ecotoxicological monitoring of ciliates in polluted habitats. Copyright 2009 Elsevier B.V. All rights reserved.

  4. Oral Vaccination with Heat-Inactivated Mycobacterium bovis Does Not Interfere with the Antemortem Diagnostic Techniques for Tuberculosis in Goats

    Directory of Open Access Journals (Sweden)

    Alvaro Roy

    2017-08-01

    Full Text Available Vaccination against tuberculosis (TB is prohibited in cattle or other species subjected to specific TB eradication campaigns, due to the interference that it may cause with the official diagnostic tests. However, immunization with a heat-inactivated (HI Mycobacterium bovis vaccine via the oral route has been suggested to overcome this issue. In this study, the main goal was to assess the interference of the HI vaccine by different routes of administration using a previous vaccination and re-vaccination (boosting protocol. TB-free kid goats were divided into three groups: oral (n = 16, intramuscular (IM; n = 16, and control (n = 16. Results showed that there was a significant difference in the percentage of animals positive to the single intradermal test (SIT and blood based interferon-gamma release assay (IGRA caused by vaccination when performed in the IM group compared to the oral group (p < 0.001. Nevertheless, no positivity to the SIT or IGRA test was observed in orally vaccinated goats regardless of the different interpretation criteria applied. None of the groups presented positive antibody titers using an in-house ELISA and samples collected 2 months after the boost. These results suggest the potential usefulness of the HI vaccine by the oral route in goats to minimize the interference on diagnostic tests (skin and IGRA tests and reducing the necessity of defined antigens to replace the traditional purified protein derivatives for diagnosis. Finally, the results pave the way to future efficacy studies in goats using different routes of HI vaccination.

  5. Diagnostic accuracy of magnetic resonance imaging techniques for treatment response evaluation in patients with high-grade glioma, a systematic review and meta-analysis

    Energy Technology Data Exchange (ETDEWEB)

    Dijken, Bart R.J. van [University of Groningen, University Medical Center Groningen Department of Radiology, Groningen (Netherlands); Laar, Peter Jan van; Hoorn, Anouk van der [University of Groningen, University Medical Center Groningen Department of Radiology, Groningen (Netherlands); University of Groningen, University Medical Center Groningen, Center for Medical Imaging-North East Netherlands, Groningen (Netherlands); Holtman, Gea A. [University of Groningen, University Medical Center Groningen, Department of General Practice, Groningen (Netherlands)

    2017-10-15

    Treatment response assessment in high-grade gliomas uses contrast enhanced T1-weighted MRI, but is unreliable. Novel advanced MRI techniques have been studied, but the accuracy is not well known. Therefore, we performed a systematic meta-analysis to assess the diagnostic accuracy of anatomical and advanced MRI for treatment response in high-grade gliomas. Databases were searched systematically. Study selection and data extraction were done by two authors independently. Meta-analysis was performed using a bivariate random effects model when ≥5 studies were included. Anatomical MRI (five studies, 166 patients) showed a pooled sensitivity and specificity of 68% (95%CI 51-81) and 77% (45-93), respectively. Pooled apparent diffusion coefficients (seven studies, 204 patients) demonstrated a sensitivity of 71% (60-80) and specificity of 87% (77-93). DSC-perfusion (18 studies, 708 patients) sensitivity was 87% (82-91) with a specificity of 86% (77-91). DCE-perfusion (five studies, 207 patients) sensitivity was 92% (73-98) and specificity was 85% (76-92). The sensitivity of spectroscopy (nine studies, 203 patients) was 91% (79-97) and specificity was 95% (65-99). Advanced techniques showed higher diagnostic accuracy than anatomical MRI, the highest for spectroscopy, supporting the use in treatment response assessment in high-grade gliomas. (orig.)

  6. Image based measurement techniques for aircraft propeller flow diagnostics : Propeller slipstream investigations at high-lift conditions and thrust reverse

    NARCIS (Netherlands)

    Roosenboom, E.W.M.

    2011-01-01

    The aim of the thesis is to measure the propeller slipstream properties (velocity and vorticity) and to assess the unsteady and instantaneous behavior of the propeller flow field at high disk loadings, zero thrust and thrust reverse using the image based measurement techniques. Along with its

  7. Diagnostic significance of gas distension technique of the stomach with gas-forming agent on CT scan of stomach cancer

    International Nuclear Information System (INIS)

    Rho, Tae Jin; Song, Chang June; Choi, Joong Chan; Park, Cheong Hee; Cho, June Sik; Rhee, Byung Chull

    1988-01-01

    CT is a valuable method for preoperative staging of patients with stomach cancers. However, in patients with poor distension of the stomach and scanty fat between the stomach and adjacent organs, CT findings may indicate a false impression of gastric wall thickening and cannot provide the precise extent of stomach cancer. We studied the usefulness of gastric distension by gas-forming agent in 28 cases of pathologically confirmed gastric cancers on CT. Comparative analysis between CT findings and surgical pathologic findings was done in 22 cases who underwent surgery. The results were as follows; 1. Conventional CT failed to define the wall thickening or masses of the stomach, in 14 cases of 23 advanced gastric cancers, while CT with gas distension technique allowed good visualization in all advanced gastric cancers. 2. In 2 cases of 5 early gastric cancers, CT with gas distension technique could detect focal thickening of the gastric wall, even less than 1cm thickness. 3. Among 13 cases with indistinguishable border between stomach and liver on conventional CT, 7 cases were diagnosed as negative invasion on CT with gas distension technique and 5 cases of these were confirmed by surgery. 4. Among 11 cases with indistinguishable border between stomach and pancreas on conventional CT, 3 cases were diagnosed as negative invasion on CT with gas distension technique, all of which were confirmed by surgery. 5. There was no significant difference between conventional CT and CT with gas distension technique of the stomach to diagnose invasion into transverse colon, transverse colon, transverse mesocolon, lymph node metastasis, and various distant metastasis.

  8. Diagnostic significance of gas distension technique of the stomach with gas-forming agent on CT scan of stomach cancer

    Energy Technology Data Exchange (ETDEWEB)

    Rho, Tae Jin; Song, Chang June; Choi, Joong Chan; Park, Cheong Hee; Cho, June Sik; Rhee, Byung Chull [Chungnam National University College of Medicine, Dajeon (Korea, Republic of)

    1988-10-15

    CT is a valuable method for preoperative staging of patients with stomach cancers. However, in patients with poor distension of the stomach and scanty fat between the stomach and adjacent organs, CT findings may indicate a false impression of gastric wall thickening and cannot provide the precise extent of stomach cancer. We studied the usefulness of gastric distension by gas-forming agent in 28 cases of pathologically confirmed gastric cancers on CT. Comparative analysis between CT findings and surgical pathologic findings was done in 22 cases who underwent surgery. The results were as follows; 1. Conventional CT failed to define the wall thickening or masses of the stomach, in 14 cases of 23 advanced gastric cancers, while CT with gas distension technique allowed good visualization in all advanced gastric cancers. 2. In 2 cases of 5 early gastric cancers, CT with gas distension technique could detect focal thickening of the gastric wall, even less than 1cm thickness. 3. Among 13 cases with indistinguishable border between stomach and liver on conventional CT, 7 cases were diagnosed as negative invasion on CT with gas distension technique and 5 cases of these were confirmed by surgery. 4. Among 11 cases with indistinguishable border between stomach and pancreas on conventional CT, 3 cases were diagnosed as negative invasion on CT with gas distension technique, all of which were confirmed by surgery. 5. There was no significant difference between conventional CT and CT with gas distension technique of the stomach to diagnose invasion into transverse colon, transverse colon, transverse mesocolon, lymph node metastasis, and various distant metastasis.

  9. Diagnostic development

    International Nuclear Information System (INIS)

    Barnett, C.F.; Brisson, D.A.; Greco, S.E.

    1978-01-01

    During the past year the far-infrared or submillimeter diagnostic research program resulted in three major developments: (1) an optically pumped 0.385-μm D 2 O-laser oscillator-amplifier system was operated at a power level of 1 MW with a line width of less than 50 MHz; (2) a conical Pyrex submillimeter laser beam dump with a retention efficiency greater than 10 4 was developed for the ion temperature Thompson scattering experiment; and (3) a new diagnostic technique was developed that makes use of the Faraday rotation of a modulated submillimeter laser beam to determine plasma current profile. Measurements of the asymmetric distortion of the H/sub α/ (6563 A) spectral line profile show that the effective toroidal drift velocity, dv/sub two vertical bars i/dT/sub i/, may be used as an indicator of plasma quality and as a complement to other ion temperature diagnostics

  10. Rare gas dependence of vibration--vibration energy transfer processes: A diagnostic technique. Applications to CH2D2 and CH3F

    International Nuclear Information System (INIS)

    Apkarian, V.A.; Weitz, E.

    1979-01-01

    The rare gas dependence of V--V rates can be used as a diagnostic technique to identify different mechanisms of vibrational energy transfer and determine the rate constants for individual kinetic steps. The method is especially useful for the identification and measurement of rates of resonant vibrational energy transfer processes. Analytical and numerical solutions of pertinent model equations are presented and their range of applicability is discussed. The technique is applied to CH 2 D 2 and CH 3 F. In CH 2 D 2 results of studies on ν 9 , [ν 1 , ν 6 ] and states in the 2000 cm -1 region are presented where the application of the technique has made it possible to identify the pathways leading to population of these states and to assign rate constants to some of the steps involved. In CH 3 F, by studying the Ar dependence of the V--V rates of the [ν 2 , ν 5 ] and [ν 1 , ν 4 ] states it has been possible to construct a complete map of energy transfer pathways which can explain all experimental observations for this system, to date. The general applicability of the technique and its potential application to other systems is also considered

  11. Investigation of radiation protection of medical staff performing medical diagnostic examinations by using PET/CT technique

    International Nuclear Information System (INIS)

    Wrzesień, Małgorzata; Napolska, Katarzyna

    2015-01-01

    Positron emission tomography (PET) is now one of the most important methods in the diagnosis of cancer diseases. Due to the rapid growth of PET/CT centres in Poland in less than a decade, radiation protection and, consequently, the assessment of worker exposure to ionising radiation, emitted mainly by the isotope 18 F, have become essential issues. The main aim of the study was to analyse the doses received by workers employed in the Medical Diagnostic Centre. The analysis comprises a physicist, three nurses, three physicians, three technicians, as well as two administrative staff employees. High-sensitivity thermoluminescent detectors (TLDs) were used to measure the doses for medical staff. The personnel was classified into categories, among them employees having direct contact with the ‘source of radiation’— 18 FDG. The TLDs were placed on the fingertips of both hands and they were also attached at the level of eye lenses, thyroid and gonads depending on the assigned category. The highest dose of radiation was observed during the administration of the 18 FDG to the patients. In the case of the physicist, the highest dose was recorded during preparation of the radiopharmaceutical— 18 FDG. The body parts most exposed to ionizing radiation are the fingertips of the thumb, index and middle finger. (paper)

  12. An assessment of the 3D geometric surrogacy of shock timing diagnostic techniques for tuning experiments on the NIF

    Energy Technology Data Exchange (ETDEWEB)

    Robey, H F; Munro, D H; Spears, B K; Marinak, M M; Jones, O S; Patel, M V; Haan, S W; Salmonson, J D; Landen, O L [Lawrence Livermore National Laboratory, Livermore, CA (United States); Boehly, T R [Laboratory for Laser Energetics, Rochester, NY (United States); Nikroo, A [General Atomics, San Diego, CA (United States)], E-mail: robey1@llnl.gov

    2008-05-15

    Ignition capsule implosions planned for the National Ignition Facility (NIF) require a pulse shape with a carefully designed series of four steps, which launch a corresponding series of shocks through the ablator and DT ice shell. The relative timing of these shocks is critical for maintaining the DT fuel on a low adiabat. The current NIF specification requires that the timing of all four shocks be tuned to an accuracy of {<=} +/- 100ps. To meet these stringent requirements, dedicated tuning experiments are being planned to measure and adjust the shock timing on NIF. These tuning experiments will be performed in a modified hohlraum geometry, where a re-entrant Au cone is added to the standard NIF hohlraum to provide optical diagnostic (VISAR and SOP) access to the shocks as they break out of the ablator. This modified geometry is referred to as the 'keyhole' hohlraum and introduces a geometric difference between these tuning-experiments and the full ignition geometry. In order to assess the surrogacy of this modified geometry, 3D simulations using HYDRA [1] have been performed. The results from simulations of a quarter of the target geometry are presented. Comparisons of the hohlraum drive conditions and the resulting effect on the shock timing in the keyhole hohlraum are compared with the corresponding results for the standard ignition hohlraum.

  13. An assessment of the 3D geometric surrogacy of shock timing diagnostic techniques for tuning experiments on the NIF

    International Nuclear Information System (INIS)

    Robey, H F; Munro, D H; Spears, B K; Marinak, M M; Jones, O S; Patel, M V; Haan, S W; Salmonson, J D; Landen, O L; Boehly, T R; Nikroo, A

    2008-01-01

    Ignition capsule implosions planned for the National Ignition Facility (NIF) require a pulse shape with a carefully designed series of four steps, which launch a corresponding series of shocks through the ablator and DT ice shell. The relative timing of these shocks is critical for maintaining the DT fuel on a low adiabat. The current NIF specification requires that the timing of all four shocks be tuned to an accuracy of ≤ +/- 100ps. To meet these stringent requirements, dedicated tuning experiments are being planned to measure and adjust the shock timing on NIF. These tuning experiments will be performed in a modified hohlraum geometry, where a re-entrant Au cone is added to the standard NIF hohlraum to provide optical diagnostic (VISAR and SOP) access to the shocks as they break out of the ablator. This modified geometry is referred to as the 'keyhole' hohlraum and introduces a geometric difference between these tuning-experiments and the full ignition geometry. In order to assess the surrogacy of this modified geometry, 3D simulations using HYDRA [1] have been performed. The results from simulations of a quarter of the target geometry are presented. Comparisons of the hohlraum drive conditions and the resulting effect on the shock timing in the keyhole hohlraum are compared with the corresponding results for the standard ignition hohlraum

  14. Investigation of radiation protection of medical staff performing medical diagnostic examinations by using PET/CT technique.

    Science.gov (United States)

    Wrzesień, Małgorzata; Napolska, Katarzyna

    2015-03-01

    Positron emission tomography (PET) is now one of the most important methods in the diagnosis of cancer diseases. Due to the rapid growth of PET/CT centres in Poland in less than a decade, radiation protection and, consequently, the assessment of worker exposure to ionising radiation, emitted mainly by the isotope (18)F, have become essential issues. The main aim of the study was to analyse the doses received by workers employed in the Medical Diagnostic Centre. The analysis comprises a physicist, three nurses, three physicians, three technicians, as well as two administrative staff employees. High-sensitivity thermoluminescent detectors (TLDs) were used to measure the doses for medical staff. The personnel was classified into categories, among them employees having direct contact with the 'source of radiation'-(18)FDG. The TLDs were placed on the fingertips of both hands and they were also attached at the level of eye lenses, thyroid and gonads depending on the assigned category. The highest dose of radiation was observed during the administration of the (18)FDG to the patients. In the case of the physicist, the highest dose was recorded during preparation of the radiopharmaceutical-(18)FDG. The body parts most exposed to ionizing radiation are the fingertips of the thumb, index and middle finger.

  15. IDENTIFICATION OF CANINE VISCERAL LEISHMANIASIS IN A PREVIOUSLY UNAFFECTED AREA BY CONVENTIONAL DIAGNOSTIC TECHNIQUES AND CELL-BLOCK FIXATION

    Directory of Open Access Journals (Sweden)

    Tuanne Rotti ABRANTES

    2016-01-01

    Full Text Available After the report of a second case of canine visceral leishmaniasis (CVL in São Bento da Lagoa, Itaipuaçu, in the municipality of Maricá, Rio de Janeiro State, an epidemiological survey was carried out, through active search, totaling 145 dogs. Indirect immunofluorescence assay (IFA, enzyme-linked immunosorbent assay (ELISA, and rapid chromatographic immunoassay based on dual-path platform (DPP(r were used to perform the serological examinations. The parasitological diagnosis of cutaneous fragments was performed by parasitological culture, histopathology, and immunohistochemistry. In the serological assessment, 21 dogs were seropositive by IFA, 17 by ELISA, and 11 by DPP(r, with sensitivity of 66.7%, 66.7% and 50%, and specificity of 87.2%, 90.2% and 94%, respectively for each technique. The immunohistochemistry of bone marrow using the cell-block technique presented the best results, with six positive dogs found, three of which tested negative by the other parasitological techniques. Leishmania sp. was isolated by parasitological culture in three dogs. The detection of autochthonous Leishmania infantum in Itaipuaçu, and the high prevalence of seropositive dogs confirm the circulation of this parasite in the study area and alert for the risk of expansion in the State of Rio de Janeiro.

  16. Systematic application of flame diagnostics techniques for performance and emissions development of modern combustion systems; Systematischer Einsatz der Flammendiagnostik fuer die Leistungs- und Emissionsentwicklung moderner Brennverfahren

    Energy Technology Data Exchange (ETDEWEB)

    Winklhofer, E.; Beidl, C.; Hirsch, A.; Piock, W. [AVL List GmbH, Graz (Austria)

    2004-07-01

    In engine engineering, the information and benefits gained from optical flame diagnostics, especially in the combination with thermodynamic and CFD analysis of airflow and combustion are well accepted. It is, however, a specific challenge to implement techniques which are well established in basic engine R and D into the processes of series development or engine calibration. Any technique taken over from successfull predevelopment applications, is expected to equally well support series development. But in order to do this, it must also be suited to easily blend into the procedures of standard multicylinder engine tests. Development speed and results quality improve consideraly, whenever engineers within their routine engine tests gain knowledge about and evaluation of flame properties which allow identification of possible improvements of combustion efficiency, power density and emissions in an early, upfront development phase. Diagnostic systems employed for such tasks make use of fiber optic sensors which in spark ignited engines may be implanted into the bodies of sensor spark plugs. Their mechanic, thermal and electric properties comply with those of the originals, thus enabling their continuous use on the test bed. The arrangement of standard fiber optic channels allows flame radiation monitoring either within the axial proximity of the sensor plug, or of the entire combustion chamber compression volume. Signal recording and signal analysis is accomplished with Visiolution system techniques. Test results are evaluated on the basis of Visiolution algorithms. Data reduction schemes provide numerical figures of merit, describing, e. g. direction, velocity and symmetry of a spark ignited flame kernel. When knock center distribution is analysed, actual distribution statistics are checked against best concept distributions, whenever diffusion flames are detected against expectations of ideal premixed flames, their position, timing and intensity is evaluated. Such

  17. Plasma Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Zaveryaev, V [Kurchatov Institute, Moscow (Russian Federation); others, and

    2012-09-15

    The success in achieving peaceful fusion power depends on the ability to control a high temperature plasma, which is an object with unique properties, possibly the most complicated object created by humans. Over years of fusion research a new branch of science has been created, namely plasma diagnostics, which involves knowledge of almost all fields of physics, from electromagnetism to nuclear physics, and up-to-date progress in engineering and technology (materials, electronics, mathematical methods of data treatment). Historically, work on controlled fusion started with pulsed systems and accordingly the methods of plasma parameter measurement were first developed for short lived and dense plasmas. Magnetically confined hot plasmas require the creation of special experimental techniques for diagnostics. The diagnostic set is the most scientifically intensive part of a plasma device. During many years of research operation some scientific tasks have been solved while new ones arose. New tasks often require significant changes in the diagnostic system, which is thus a very flexible part of plasma machines. Diagnostic systems are designed to solve several tasks. As an example here are the diagnostic tasks for the International Thermonuclear Experimental Reactor - ITER: (1) Measurements for machine protection and basic control; (2) Measurements for advanced control; (3) Additional measurements for performance evaluation and physics. Every new plasma machine is a further step along the path to the main goal - controlled fusion - and nobody knows in advance what new phenomena will be met on the way. So in the planning of diagnostic construction we should keep in mind further system upgrading to meet possible new scientific and technical challenges. (author)

  18. Veterinary Molecular Diagnostics

    NARCIS (Netherlands)

    Roest, H.I.J.; Engelsma, M.Y.; Weesendorp, E.; Bossers, A.; Elbers, A.R.W.

    2017-01-01

    In veterinary molecular diagnostics, samples originating from animals are tested. Developments in the farm animals sector and in our societal attitude towards pet animals have resulted in an increased demand for fast and reliable diagnostic techniques. Molecular diagnostics perfectly matches this

  19. On Thermoeconomic Diagnosis of a Fouled Direct Expansion Coil: Effects of Induced Malfunctions on Quantitative Performance of the Diagnostic Technique

    Directory of Open Access Journals (Sweden)

    Antonio Piacentino

    2017-06-01

    Full Text Available Thermoeconomic diagnosis represents a promising technique for the detection ofcommon faults in refrigeration systems, which are responsible of degradation in theirenergetic performance. Recently, the authors have carried out a sensitivity analysis of theperformance of this method to the thermodynamic conditions of inlet air and to thegeometry of the direct expansion coil, in case of degradation induced by evaporatorfouling. The analysis showed that the method is able to detect this fault, but sometimes itsquantitative assessments are not satisfactory. In order to understand more in-depth theorigin of such results and identify margins for refinement of the technique, this paper isaimed at evaluating at what extent changes in the exergetic performance of faults-freecomponents may negatively influence the model capability to detect the fouledevaporator and quantify the consequent additional exergy consumption. The resultssuggest that the method is particularly sensitive to the cost of “induced malfunctions” onthe compressor and the condenser, especially when low coil depth or high relativehumidity of inlet air are considered.

  20. 2D and 3D optical diagnostic techniques applied to Madonna dei Fusi by Leonardo da Vinci

    Science.gov (United States)

    Fontana, R.; Gambino, M. C.; Greco, M.; Marras, L.; Materazzi, M.; Pampaloni, E.; Pelagotti, A.; Pezzati, L.; Poggi, P.; Sanapo, C.

    2005-06-01

    3D measurement and modelling have been traditionally applied to statues, buildings, archeological sites or similar large structures, but rarely to paintings. Recently, however, 3D measurements have been performed successfully also on easel paintings, allowing to detect and document the painting's surface. We used 3D models to integrate the results of various 2D imaging techniques on a common reference frame. These applications show how the 3D shape information, complemented with 2D colour maps as well as with other types of sensory data, provide the most interesting information. The 3D data acquisition was carried out by means of two devices: a high-resolution laser micro-profilometer, composed of a commercial distance meter mounted on a scanning device, and a laser-line scanner. The 2D data acquisitions were carried out using a scanning device for simultaneous RGB colour imaging and IR reflectography, and a UV fluorescence multispectral image acquisition system. We present here the results of the techniques described, applied to the analysis of an important painting of the Italian Reinassance: `Madonna dei Fusi', attributed to Leonardo da Vinci.

  1. Assessment of African Swine Fever Diagnostic Techniques as a Response to the Epidemic Outbreaks in Eastern European Union Countries: How To Improve Surveillance and Control Programs.

    Science.gov (United States)

    Gallardo, C; Nieto, R; Soler, A; Pelayo, V; Fernández-Pinero, J; Markowska-Daniel, I; Pridotkas, G; Nurmoja, I; Granta, R; Simón, A; Pérez, C; Martín, E; Fernández-Pacheco, P; Arias, M

    2015-08-01

    This study represents a complete comparative analysis of the most widely used African swine fever (ASF) diagnostic techniques in the European Union (EU) using field and experimental samples from animals infected with genotype II ASF virus (ASFV) isolates circulating in Europe. To detect ASFV, three different PCRs were evaluated in parallel using 785 field and experimental samples. The results showed almost perfect agreement between the Universal ProbeLibrary (UPL-PCR) and the real-time (κ = 0.94 [95% confidence interval {CI}, 0.91 to 0.97]) and conventional (κ = 0.88 [95% CI, 0.83 to 0.92]) World Organisation for Animal Health (OIE)-prescribed PCRs. The UPL-PCR had greater diagnostic sensitivity for detecting survivors and allows earlier detection of the disease. Compared to the commercial antigen enzyme-linked immunosorbent assay (ELISA), good-to-moderate agreement (κ = 0.67 [95% CI, 0.58 to 0.76]) was obtained, with a sensitivity of 77.2% in the commercial test. For ASF antibody detection, five serological methods were tested, including three commercial ELISAs, the OIE-ELISA, and the confirmatory immunoperoxidase test (IPT). Greater sensitivity was obtained with the IPT than with the ELISAs, since the IPT was able to detect ASF antibodies at an earlier point in the serological response, when few antibodies are present. The analysis of the exudate tissues from dead wild boars showed that IPT might be a useful serological tool for determining whether or not animals had been exposed to virus infection, regardless of whether antibodies were present. In conclusion, the UPL-PCR in combination with the IPT was the most trustworthy method for detecting ASF during the epidemic outbreaks affecting EU countries in 2014. The use of the most appropriate diagnostic tools is critical when implementing effective control programs. Copyright © 2015, American Society for Microbiology. All Rights Reserved.

  2. Assessment of African Swine Fever Diagnostic Techniques as a Response to the Epidemic Outbreaks in Eastern European Union Countries: How To Improve Surveillance and Control Programs

    Science.gov (United States)

    Nieto, R.; Soler, A.; Pelayo, V.; Fernández-Pinero, J.; Markowska-Daniel, I.; Pridotkas, G.; Nurmoja, I.; Granta, R.; Simón, A.; Pérez, C.; Martín, E.; Fernández-Pacheco, P.; Arias, M.

    2015-01-01

    This study represents a complete comparative analysis of the most widely used African swine fever (ASF) diagnostic techniques in the European Union (EU) using field and experimental samples from animals infected with genotype II ASF virus (ASFV) isolates circulating in Europe. To detect ASFV, three different PCRs were evaluated in parallel using 785 field and experimental samples. The results showed almost perfect agreement between the Universal ProbeLibrary (UPL-PCR) and the real-time (κ = 0.94 [95% confidence interval {CI}, 0.91 to 0.97]) and conventional (κ = 0.88 [95% CI, 0.83 to 0.92]) World Organisation for Animal Health (OIE)-prescribed PCRs. The UPL-PCR had greater diagnostic sensitivity for detecting survivors and allows earlier detection of the disease. Compared to the commercial antigen enzyme-linked immunosorbent assay (ELISA), good-to-moderate agreement (κ = 0.67 [95% CI, 0.58 to 0.76]) was obtained, with a sensitivity of 77.2% in the commercial test. For ASF antibody detection, five serological methods were tested, including three commercial ELISAs, the OIE-ELISA, and the confirmatory immunoperoxidase test (IPT). Greater sensitivity was obtained with the IPT than with the ELISAs, since the IPT was able to detect ASF antibodies at an earlier point in the serological response, when few antibodies are present. The analysis of the exudate tissues from dead wild boars showed that IPT might be a useful serological tool for determining whether or not animals had been exposed to virus infection, regardless of whether antibodies were present. In conclusion, the UPL-PCR in combination with the IPT was the most trustworthy method for detecting ASF during the epidemic outbreaks affecting EU countries in 2014. The use of the most appropriate diagnostic tools is critical when implementing effective control programs. PMID:26041901

  3. Plasma diagnostics discharge parameters and chemistry

    CERN Document Server

    Auciello, Orlando

    1989-01-01

    Plasma Diagnostics, Volume 1: Discharge Parameters and Chemistry covers seven chapters on the important diagnostic techniques for plasmas and details their use in particular applications. The book discusses optical diagnostic techniques for low pressure plasmas and plasma processing; plasma diagnostics for electrical discharge light sources; as well as Langmuir probes. The text also describes the mass spectroscopy of plasmas, microwave diagnostics, paramagnetic resonance diagnostics, and diagnostics in thermal plasma processing. Electrical engineers, nuclear engineers, microwave engineers, che

  4. Diagnostic Value of Multidetector CT and Its Multiplanar Reformation, Volume Rendering and Virtual Bronchoscopy Postprocessing Techniques for Primary Trachea and Main Bronchus Tumors.

    Directory of Open Access Journals (Sweden)

    Mingyue Luo

    Full Text Available To evaluate the diagnostic value of multidetector CT (MDCT and its multiplanar reformation (MPR, volume rendering (VR and virtual bronchoscopy (VB postprocessing techniques for primary trachea and main bronchus tumors.Detection results of 31 primary trachea and main bronchus tumors with MDCT and its MPR, VR and VB postprocessing techniques, were analyzed retrospectively with regard to tumor locations, tumor morphologies, extramural invasions of tumors, longitudinal involvements of tumors, morphologies and extents of luminal stenoses, distances between main bronchus tumors and trachea carinae, and internal features of tumors. The detection results were compared with that of surgery and pathology.Detection results with MDCT and its MPR, VR and VB were consistent with that of surgery and pathology, included tumor locations (tracheae, n = 19; right main bronchi, n = 6; left main bronchi, n = 6, tumor morphologies (endoluminal nodes with narrow bases, n = 2; endoluminal nodes with wide bases, n = 13; both intraluminal and extraluminal masses, n = 16, extramural invasions of tumors (brokethrough only serous membrane, n = 1; 4.0 mm-56.0 mm, n = 14; no clear border with right atelectasis, n = 1, longitudinal involvements of tumors (3.0 mm, n = 1; 5.0 mm-68.0 mm, n = 29; whole right main bronchus wall and trachea carina, n = 1, morphologies of luminal stenoses (irregular, n = 26; circular, n = 3; eccentric, n = 1; conical, n = 1 and extents (mild, n = 5; moderate, n = 7; severe, n = 19, distances between main bronchus tumors and trachea carinae (16.0 mm, n = 1; invaded trachea carina, n = 1; >20.0 mm, n = 10, and internal features of tumors (fairly homogeneous densities with rather obvious enhancements, n = 26; homogeneous density with obvious enhancement, n = 1; homogeneous density without obvious enhancement, n = 1; not enough homogeneous density with obvious enhancement, n = 1; punctate calcification with obvious enhancement, n = 1; low density

  5. Diagnostic Value of Multidetector CT and Its Multiplanar Reformation, Volume Rendering and Virtual Bronchoscopy Postprocessing Techniques for Primary Trachea and Main Bronchus Tumors.

    Science.gov (United States)

    Luo, Mingyue; Duan, Chaijie; Qiu, Jianping; Li, Wenru; Zhu, Dongyun; Cai, Wenli

    2015-01-01

    To evaluate the diagnostic value of multidetector CT (MDCT) and its multiplanar reformation (MPR), volume rendering (VR) and virtual bronchoscopy (VB) postprocessing techniques for primary trachea and main bronchus tumors. Detection results of 31 primary trachea and main bronchus tumors with MDCT and its MPR, VR and VB postprocessing techniques, were analyzed retrospectively with regard to tumor locations, tumor morphologies, extramural invasions of tumors, longitudinal involvements of tumors, morphologies and extents of luminal stenoses, distances between main bronchus tumors and trachea carinae, and internal features of tumors. The detection results were compared with that of surgery and pathology. Detection results with MDCT and its MPR, VR and VB were consistent with that of surgery and pathology, included tumor locations (tracheae, n = 19; right main bronchi, n = 6; left main bronchi, n = 6), tumor morphologies (endoluminal nodes with narrow bases, n = 2; endoluminal nodes with wide bases, n = 13; both intraluminal and extraluminal masses, n = 16), extramural invasions of tumors (brokethrough only serous membrane, n = 1; 4.0 mm-56.0 mm, n = 14; no clear border with right atelectasis, n = 1), longitudinal involvements of tumors (3.0 mm, n = 1; 5.0 mm-68.0 mm, n = 29; whole right main bronchus wall and trachea carina, n = 1), morphologies of luminal stenoses (irregular, n = 26; circular, n = 3; eccentric, n = 1; conical, n = 1) and extents (mild, n = 5; moderate, n = 7; severe, n = 19), distances between main bronchus tumors and trachea carinae (16.0 mm, n = 1; invaded trachea carina, n = 1; >20.0 mm, n = 10), and internal features of tumors (fairly homogeneous densities with rather obvious enhancements, n = 26; homogeneous density with obvious enhancement, n = 1; homogeneous density without obvious enhancement, n = 1; not enough homogeneous density with obvious enhancement, n = 1; punctate calcification with obvious enhancement, n = 1; low density without

  6. Development of automatic extraction of the corpus callosum from magnetic resonance imaging of the head and examination of the early dementia objective diagnostic technique in feature analysis

    International Nuclear Information System (INIS)

    Kodama, Naoki; Kaneko, Tomoyuki

    2005-01-01

    We examined the objective diagnosis of dementia based on changes in the corpus callosum. We examined midsagittal head MR images of 17 early dementia patients (2 men and 15 women; mean age, 77.2±3.3 years) and 18 healthy elderly controls (2 men and 16 women; mean age, 73.8±6.5 years), 35 subjects altogether. First, the corpus callosum was automatically extracted from the MR images. Next, early dementia was compared with the healthy elderly individuals using 5 features of the straight-line methods, 5 features of the Run-Length Matrix, and 6 features of the Co-occurrence Matrix from the corpus callosum. Automatic extraction of the corpus callosum showed an accuracy rate of 84.1±3.7%. A statistically significant difference was found in 6 of the 16 features between early dementia patients and healthy elderly controls. Discriminant analysis using the 6 features demonstrated a sensitivity of 88.2% and specificity of 77.8%, with an overall accuracy of 82.9%. These results indicate that feature analysis based on changes in the corpus callosum can be used as an objective diagnostic technique for early dementia. (author)

  7. Practical X-ray diagnostics orthopedics and trauma surgery. Indication, adjustment technique and radiation protection; Praktische Roentgendiagnostik Orthopaedie und Unfallchirurgie. Indikation, Einstelltechnik, Strahlenschutz

    Energy Technology Data Exchange (ETDEWEB)

    Flechtenmacher, Johannes [Ortho-Zentrum am Ludwigsplatz, Karlsruhe (Germany); Sabo, Desiderius [Klinik St. Elisabeth, Heidelberg (Germany). Sportopaedic Heidelberg

    2014-07-01

    The book on X-ray diagnostics in orthopedics and trauma surgery includes the following chapters: 1. Introduction: radiation protection, equipment technology radiological diagnostics of skeleton carcinomas, specific aspects of trauma surgery, special aspects of skeleton radiology for children. 2. X-ray diagnostics of different anatomical regions: ankle joint, knee, hips and pelvis, hand and wrist joint, elbow, shoulder, spinal cord. 3. Appendix: radiation protection according to the X-ray regulations.

  8. Diagnostic Development on NSTX

    International Nuclear Information System (INIS)

    A.L. Roquemore; D. Johnson; R. Kaita; et al

    1999-01-01

    Diagnostics are described which are currently installed or under active development for the newly commissioned NSTX device. The low aspect ratio (R/a less than or equal to 1.3) and low toroidal field (0.1-0.3T) used in this device dictate adaptations in many standard diagnostic techniques. Technical summaries of each diagnostic are given, and adaptations, where significant, are highlighted

  9. Use of sting-response techniques for simulate diagnostics in human esophagus; Uso de tecnicas estimulo-respuesta para simular diagnosticos en esofago humano

    Energy Technology Data Exchange (ETDEWEB)

    Rodriguez, I.; Gonzalez, Y.; Valdes, L.; Alfonso, J.A.; Estevez, E. [Facultad de Quimica Farmacia, Universidad Central de Las Villas (Cuba)

    2003-07-01

    In this work a study of simulation of the gamma graphic studies that are carried out in human esophagus in the Dept. of Nuclear Medicine of the 'Celestino Hernandez Robau Hospital of Santa Clara is presented. For the investigation tubular reactors were used and sting-response techniques with radioactive tracer of Technetium 99 metastable to a concentration of 1 mCi and several flows were applied. The distribution curves of residences times were obtained, those that respond to an equation of the type: Y = A + B exp (- exp((x-C)/D)) - ((x-C/D)+1). They were also carried out, optimizations studies of the doses of the radioactive to give to the patients from 1 mCi (that is the one used in studies) up to 0,5 mCi, and the influences on the obtained distributions of residence time were analyzed. It was confirmed the possibility to lower the doses with clear information of the signal. It was also carried out a simulation of the attenuation of the radiations that takes place in the patients by the interposition of tissues among the analyzed organ, and the detection equipment. It was used paraffin for tissue simulation. It was found the almost independence of the intensity of the radiations with the thickness, for the assayed doses. Lastly it was found a complex mathematical model that responds to the diagnostic curves obtained in these studies, being correlated the coefficients of the pattern with the most important physical parameters of the system, giving it a practical and useful value, all time that the error among the values that this it predicts and the experimental ones do not surpass of 5%. (Author)

  10. Taenia solium porcine cysticercosis in Madagascar: Comparison of immuno-diagnostic techniques and estimation of the prevalence in pork carcasses traded in Antananarivo city.

    Science.gov (United States)

    Porphyre, V; Betson, M; Rabezanahary, H; Mboussou, Y; Zafindraibe, N J; Rasamoelina-Andriamanivo, H; Costard, S; Pfeiffer, D U; Michault, A

    2016-03-30

    Taenia solium cysticercosis was reported in official veterinary and medical statistics to be highly prevalent in pigs and humans in Madagascar, but few estimates are available for pigs. This study aimed to estimate the seroprevalence of porcine cysticercosis among pigs slaughtered in Antananarivo abattoirs. Firstly, the diagnostic performance of two antigen-ELISA techniques (B158B60 Ag-ELISA and HP10 Ag-ELISA) and an immunoblotting method were compared with meat inspection procedures on a sample of pigs suspected to be infected with (group 1; n=250) or free of (group 2; n=250) T. solium based on direct veterinary inspection in Madagascar. Sensitivity and specificity of the antigen ELISAs were then estimated using a Bayesian approach for detection of porcine cysticercosis in the absence of a gold standard. Then, a third set of pig sera (group 3, n=250) was randomly collected in Antananarivo slaughterhouses and tested to estimate the overall prevalence of T. solium contamination in pork meat traded in Antananarivo. The antigen ELISAs showed a high sensitivity (>84%), but the B158B60 Ag-ELISA appeared to be more specific than the HP10 Ag-ELISA (model 1: 95% vs 74%; model 2: 87% vs 71%). The overall prevalence of porcine cysticercosis in Antananarivo slaughterhouses was estimated at 2.3% (95% credibility interval [95%CrI]: 0.09-9.1%) to 2.6% (95%CrI: 0.1-10.3%) depending on the model and priors used. Since the sample used in this study is not representative of the national pig population, village-based surveys and longitudinal monitoring at slaughter are needed to better estimate the overall prevalence, geographical patterns and main risk factors for T. solium contamination, in order to improve control policies. Copyright © 2015 Elsevier B.V. All rights reserved.

  11. Molecular characterization of the rDNA-ITS sequence and a PCR diagnostic technique for Pileolaria terebinthi, the cause of pistachio rust

    Directory of Open Access Journals (Sweden)

    Hossein ALAEI

    2013-01-01

    Full Text Available Eleven samples of the most important pistachio rust (caused by Pileolaria terebinthi (DC. Cast.,, which causes disease on Beneh (Pistacia atlantica Desf. subsp. mutica (Fisch. & Mey. Rech. F and Kasoor (Pistacia khinjuk Stocks., were collected from herbarium specimens and pistachio fields at the Pistachio Research Institute in Rafsanjan, Iran. The complete sequences of ribosomal DNA internal transcribed spacers ITS1 and ITS2 (rDNA ITS from the samples were determined and analysed. In general, very little rDNA ITS sequence variation was observed between rDNA ITS sequences of P. terebinthi samples. The length of the PCR fragments was 621 bp (for ITS1F-ITS4 and 1177 bp (for ITS1F-rust1, and consisted of 67 bp at the 3 ́ end of 18S rDNA, 93 bp of ITS1 region, 154 bp of 5.8S rDNA, 246 bp of the ITS2 region, 57 bp (for ITS1F-ITS4 and 613 bp (for ITS1F-rust1 at the 5 ́ end of the 28S rDNA. Restriction fragment length polymorphisms (RFLPs of the rDNA-ITS region were used to identify Pileolaria terebinthi. Three strong bands of 105, 134 and 381 bp and five bands of 105, 134, 200, 301 and 437 bp are observed for the fragment of “ITS1F-ITS4” and “ITS1F-rust1”, respectively. A PCR-RFLP diagnostic technique provided effective identification of the species by a unique pattern with the specific restriction enzyme XapI (ApoI.

  12. Molecular diagnostics of periodontitis

    OpenAIRE

    Izabela Korona-Głowniak; Radosław Siwiec; Marcin Berger; Anna Malm; Jolanta Szymańska

    2017-01-01

    The microorganisms that form dental plaque are the main cause of periodontitis. Their identification and the understanding of the complex relationships and interactions that involve these microorganisms, environmental factors and the host’s health status enable improvement in diagnostics and targeted therapy in patients with periodontitis. To this end, molecular diagnostics techniques (both techniques based on the polymerase chain reaction and those involving nucleic acid analysis via hybridi...

  13. Plasma diagnostics for tokamaks and stellarators

    Energy Technology Data Exchange (ETDEWEB)

    Stott, P E; Sanchez, J

    1994-07-01

    A collection of papers on plasma diagnostics is presented. The papers show the state of the art developments in a series of techniques: Magnetic diagnostics, Edge diagnostics, Langmuir probes, Spectroscopy, Microwave and FIR diagnostics as well as Thomson Scattering. Special interest was focused on those diagnostics oriented to fluctuations measurements in the plasma. (Author) 451 refs.

  14. Plasma diagnostics for tokamaks and stellarators

    International Nuclear Information System (INIS)

    Stott, P.E.; Sanchez, J.

    1994-01-01

    A collection of papers on plasma diagnostics is presented. The papers show the state of the art developments in a series of techniques: magnetic diagnostics, Edge diagnostics, Langmuir probes, Spectroscopy, Microwave and FIR diagnostics as well as Thomson Sattering. Special interest was focused on those diagnostics oriented to fluctuations measurements in the plasma

  15. Narrowing of the Diagnostic Gap of Acute Gastroenteritis in Children 0-6 Years of Age Using a Combination of Classical and Molecular Techniques, Delivers Challenges in Syndromic Approach Diagnostics.

    Science.gov (United States)

    Steyer, Andrej; Jevšnik, Monika; Petrovec, Miroslav; Pokorn, Marko; Grosek, Štefan; Fratnik Steyer, Adela; Šoba, Barbara; Uršič, Tina; Cerar Kišek, Tjaša; Kolenc, Marko; Trkov, Marija; Šparl, Petra; Duraisamy, Raja; Lipkin, W Ian; Terzić, Sara; Kolnik, Mojca; Mrvič, Tatjana; Kapoor, Amit; Strle, Franc

    2016-09-01

    Twenty-five percent to 50% of acute gastroenteritis (AGE) cases remain etiologically undiagnosed. Our main aim was to determine the most appropriate list of enteric pathogens to be included in the daily diagnostics scheme of AGE, ensuring the lowest possible diagnostic gap. Two hundred ninety seven children ≤6 years of age, admitted to hospital in Slovenia, October 2011 to October 2012, with AGE, and 88 ≤6 years old healthy children were included in the study. A broad spectrum of enteric pathogens was targeted with molecular methods, including 8 viruses, 6 bacteria and 2 parasites. At least one enteric pathogen was detected in 91.2% of cases with AGE and 27.3% of controls. Viruses were the most prevalent (82.5% and 15.9%), followed by bacteria (27.3% and 10.2%) and parasites (3.0% and 1.1%) in cases and controls, respectively. A high proportion (41.8%) of mixed infections was observed in the cases. For cases with undetermined etiology (8.8%), stool samples were analyzed with next generation sequencing, and a potential viral pathogen was detected in 17 additional samples (5.8%). Our study suggests that tests for rotaviruses, noroviruses genogroup II, adenoviruses 40/41, astroviruses, Campylobacter spp. and Salmonella sp. should be included in the initial diagnostic algorithm, which revealed the etiology in 83.5% of children tested. The use of molecular methods in diagnostics of gastroenteritis is preferable because of their high sensitivity, specificity, fast performance and the possibility of establishing the concentration of the target. The latter may be valuable for assessing the clinical significance of the detected enteric, particularly viral pathogens.

  16. Flowfield modeling and diagnostics

    International Nuclear Information System (INIS)

    Gupta, A.K.; Lilley, D.G.

    1985-01-01

    This textbook is devoted solely to flowfield modeling and diagnostics; their practical use, recent and current research, and projected developments and trends. It provides an account of the use of a broad range of techniques in industrial and research practice, both with and without combustion. Application ideas are complemented by details about experimental and modeling techniques

  17. Summary receiver operating characteristic curves as a technique for meta-analysis of the diagnostic performance of duplex ultrasonography in peripheral arterial disease

    NARCIS (Netherlands)

    deVries, SO; Hunink, MGM; Polak, JF

    Rationale and Objectives. We summarized and compared the diagnostic performance of duplex and color-guided duplex ultrasonography in the evaluation of peripheral arterial disease. We present our research as an example of the use of summary receiver operating characteristic (ROC) curves in a

  18. Angiography - interventional diagnostic applications

    International Nuclear Information System (INIS)

    Schild, H.

    1994-01-01

    The angiography system is very different from the other systems used in diagnostic radiology. The invasivity of angiography requires special, high standards in theoretical and practical training and experience both of beginners and experienced personnel. This textbook fully meets the demand for in-depth and exhaustive information, as it presents: - The fundamentals and techniques of angiography, the vascular anatomy, and many hints and tips of great help in practice. - A comprehensive survey of diagnostic problems and examination approaches, including neuro-angiography, with 221 reproductions of original angiographs, and additional schematic representations. - A special chapter devoted to indication and relevant techniques for the major vascular interventional examinations. - A great number of tables explain at a glance standard examination techniques, indications and diagnostic criteria. (orig./CB) [de

  19. Diagnostic planning in JT-60 project

    International Nuclear Information System (INIS)

    Matoba, Tohru; Suzuki, Yasuo; Funahashi, Akimasa; Itagaki, Tokiyoshi

    1977-08-01

    The diagnostic plans of JT-60 were made along with design of the main machine. Basic requirements of the diagnostic program are (1) multiple measurement of respective plasma parameters, (2) efficient usage of the discharge, (3) capable data acquisition system, (4) high reliability of the diagnostic equipments, and (5) systematic development of new diagnostic techniques. Dimensions of the diagnostic ports were determined in detailed design of the vacuum vessel, anticipating the possible diagnostic methods. The proposed diagnostic systems and the plans are shown in table and figures respectively. Problems in the diagnostics are also described. (auth.)

  20. Intercomparison of techniques for inspection and diagnostics of heavy water reactor pressure tubes: Flaw detection and characterization [Phase 1] [Sample summary reports of pressure tube samples from Argentina, India, Canada, Republic of Korea, and Romania

    International Nuclear Information System (INIS)

    2006-05-01

    Nuclear power plants with heavy water reactors (HWRs) comprise nine percent of today's operating nuclear units, and more are under construction. Efficient and accurate inspection and diagnostic techniques for various reactor components and systems are an important factor in assuring reliable and safe plant operation. To foster international collaboration in the efficient and safe use of nuclear power, the IAEA conducted a Coordinated Research Programme (CRP) on Inter-comparison of Techniques for HWR Pressure Tube Inspection and Diagnostics. This CRP was carried out within the frame of the IAEA Department of Nuclear Energy's Technical Working Group on Advanced Technologies for HWRs (the TWG-HWR). The TWG-HWR is a group of experts nominated by their governments and designated by the IAEA to provide advice and to support implementation of the IAEA's project on advanced technologies for HWRs. The objective of the CRP was to inter-compare non-destructive inspection and diagnostic techniques, in use and being developed, for structural integrity assessment of HWR pressure tubes. During the first phase of this CRP, participants have investigated the capability of different techniques to detect and characterize flaws. During the second phase of this CRP, participants collaborated to detect and characterize hydride blisters and to determine the hydrogen concentration in Zirconium alloys. The intent was to identify the most effective pressure tube inspection and diagnostic methods, and to identify further development needs. The organizations that have participated in this CRP are: - The Comision Nacional de Energia Atomica (CNEA), Argentina; - Atomic Energy of Canada Ltd. (AECL); Chalk River Laboratories (CRL), Canada; - The Research Institute of Nuclear Power Operations (RINPO), China National Nuclear Corporation (CNNC), China; - Bhabha Atomic Research Centre (BARC), India; - The Korea Electric Power Research Institute (KEPRI), Republic of Korea; - The Korea Atomic Energy

  1. A Partnership Training Program in Breast Cancer Diagnosis: Concept Development of the Next Generation Diagnostic Breast Imaging Using Digital Image Library and Networking Techniques

    National Research Council Canada - National Science Library

    Chouikha, Mohamed F

    2004-01-01

    ...); and Georgetown University (Image Science and Information Systems, ISIS). In this partnership training program, we will train faculty and students in breast cancer imaging, digital image database library techniques and network communication strategy...

  2. Influence of diagnostic quality scanning technique with CR mammography; Influencia de la tecnica de exploracion en la calidad diagnostica de la mamografia ocn CR

    Energy Technology Data Exchange (ETDEWEB)

    Rivas Ballarin, M. A.; Ruiz Manzano, P.; Ortega Pardina, P.; Laliena Bielsa, V.; Calvo Carrillo, S.; Garcia Romero, A.; Millan Cebrian, E.

    2013-07-01

    Image quality criteria laid down in the Spanish Protocol of Control of quality in Radiology (PECCR) to a team of mammography with CR imaging system are applied in this work and evaluated the dosimetry impact implied by the modification of the technique of exposure required for the fulfilment of those criteria. Is also analyzes the impact on the image quality of the new radiographic technique, evaluated by three radiologists. (Author)

  3. Molecular Diagnostics

    OpenAIRE

    Choe, Hyonmin; Deirmengian, Carl A.; Hickok, Noreen J.; Morrison, Tiffany N.; Tuan, Rocky S.

    2015-01-01

    Orthopaedic infections are complex conditions that require immediate diagnosis and accurate identification of the causative organisms to facilitate appropriate management. Conventional methodologies for diagnosis of these infections sometimes lack accuracy or sufficient rapidity. Current molecular diagnostics are an emerging area of bench-to-bedside research in orthopaedic infections. Examples of promising molecular diagnostics include measurement of a specific biomarker in the synovial fluid...

  4. β-trace protein as a diagnostic marker for perilymphatic fluid fistula: a prospective controlled pilot study to test a sample collection technique.

    Science.gov (United States)

    Bachmann-Harildstad, Gregor; Stenklev, Niels Christian; Myrvoll, Elin; Jablonski, Greg; Klingenberg, Olav

    2011-01-01

    The diagnosis of perilymphatic fluid (PLF) fistula is still challenging. Perilymphatic fluid fistula is one possible complication after stapedotomy or cochlear implant surgery. We have performed a prospective diagnostic pilot study to further investigate β-trace protein (β-TP) as a marker for PLF fistula. In this pilot study, we tested the sensitivity of the β-TP marker using a simple method for sample collection from the tympanic cavity. Prospective controlled diagnostic study. Two-center tertiary referral hospitals. A total of 35 adult patients undergoing ear surgery were included. Subjects were divided into 2 groups: 1) 19 patients undergoing stapedotomy were investigated for PLF fistula in samples obtained from the tympanic cavity and 2) 16 patients undergoing myringoplasty were investigated for PLF fistula in samples from the tympanic cavity. This group served as the control. Mean age +/- SD at surgery was 49.9 +/- 8.0 years in the study group and 39.69 +/- 15.47 years in the control group. β-Trace protein (prostaglandin D synthase) in tympanic cavity samples and serum samples was analyzed. The samples were collected by gradually filling the tympanic cavity with 100 to 200 μl sodium chloride and by immediately collecting a volume of 60 to 100 μl in a mucus specimen set container. The concentration of β-TP was quantified using laser nephelometry. The median β-TP in the study group was 0.8 mg/L (range, 0.05-4.5 mg/L). In the control group, the median β-TP value was 0.16 mg/L (range, 0.01-0.36 mg/L). Thirty-five percent of the values in the study group were below the highest value in the negative control group. The β-TP values of the tympanic cavity samples were significantly higher in the study group than in controls (p = 0.0001). The serum values were 0.55 +/- 0.18 and 0.53 +/- 0.11 mg/L, respectively. It may be feasible to test for PLF fistula using β-TP in samples from the tympanic cavity. Our results, however, suggest a relative low diagnostic

  5. Diagnostic imaging of craniopharyngioma

    International Nuclear Information System (INIS)

    Gradzki, J.; Nowak, S.; Paprzycki, W.

    1993-01-01

    40 patients have been examined with operational and histological confirmation of craniopharyngioma. CT image and X-ray plane of skull were performed in case all of these patients. TMR was conformed to examine 4 patients. X-ray planes was compared to CT. CT permits tumor cyst detection. The efficacy of mentioned above diagnostic techniques was compared with surgical findings. (author)

  6. Diagnostic studies in amyloidosis

    NARCIS (Netherlands)

    Hazenberg, Bouke Pier Cornelis

    2007-01-01

    In this thesis two diagnostic techniques are studied in amyloidosis. Systemic amyloidosis is characterized by deposition of amyloid fibrils (tiny fibres) throughout the body resulting in damage of vital organs. Amyloid can be detected in a tissue specimen stained with Congo red: red-stained amyloid

  7. Companion diagnostics

    DEFF Research Database (Denmark)

    Jørgensen, Jan Trøst; Hersom, Maria

    2016-01-01

    of disease mechanisms, things are slowly changing. Within the last few years, we have seen an increasing number of predictive biomarker assays being developed to guide the use of targeted cancer drugs. This type of assay is called companion diagnostics and is developed in parallel to the drug using the drug-diagnostic...... co-development model. The development of companion diagnostics is a relatively new discipline and in this review, different aspects will be discussed including clinical and regulatory issues. Furthermore, examples of drugs, such as the ALK and PD-1/PD-L1 inhibitors, that have been approved recently....... Despite having discussed personalized medicine for more than a decade, we still see that most drug prescriptions for severe chronic diseases are largely based on 'trial and error' and not on solid biomarker data. However, with the advance of molecular diagnostics and a subsequent increased understanding...

  8. Pitfalls in diagnostic radiology

    Energy Technology Data Exchange (ETDEWEB)

    Peh, Wilfred C.G. (ed.) [Khoo Teck Puat Hospital (Singapore). Dept. of Diagnostic Radiology

    2015-04-01

    Only textbook to focus primarily on the topic of pitfalls in diagnostic radiology. Highlights the pitfalls in a comprehensive and systematic manner. Written by experts in different imaging modalities and subspecialties from reputable centers across the world. The practice of diagnostic radiology has become increasingly complex, with the use of numerous imaging modalities and division into many subspecialty areas. It is becoming ever more difficult for subspecialist radiologists, general radiologists, and residents to keep up with the advances that are occurring year on year, and this is particularly true for less familiar topics. Failure to appreciate imaging pitfalls often leads to diagnostic error and misinterpretation, and potential medicolegal problems. Diagnostic errors may be due to various factors such as inadequate imaging technique, imaging artifacts, failure to recognize normal structures or variants, lack of correlation with clinical and other imaging findings, and poor training or inexperience. Many, if not most, of these factors are potentially recognizable, preventable, or correctable. This textbook, written by experts from reputable centers across the world, systematically and comprehensively highlights the pitfalls that may occur in diagnostic radiology. Both pitfalls specific to different modalities and techniques and those specific to particular organ systems are described with the help of numerous high-quality illustrations. Recognition of these pitfalls is crucial in helping the practicing radiologist to achieve a more accurate diagnosis.

  9. Pitfalls in diagnostic radiology

    International Nuclear Information System (INIS)

    Peh, Wilfred C.G.

    2015-01-01

    Only textbook to focus primarily on the topic of pitfalls in diagnostic radiology. Highlights the pitfalls in a comprehensive and systematic manner. Written by experts in different imaging modalities and subspecialties from reputable centers across the world. The practice of diagnostic radiology has become increasingly complex, with the use of numerous imaging modalities and division into many subspecialty areas. It is becoming ever more difficult for subspecialist radiologists, general radiologists, and residents to keep up with the advances that are occurring year on year, and this is particularly true for less familiar topics. Failure to appreciate imaging pitfalls often leads to diagnostic error and misinterpretation, and potential medicolegal problems. Diagnostic errors may be due to various factors such as inadequate imaging technique, imaging artifacts, failure to recognize normal structures or variants, lack of correlation with clinical and other imaging findings, and poor training or inexperience. Many, if not most, of these factors are potentially recognizable, preventable, or correctable. This textbook, written by experts from reputable centers across the world, systematically and comprehensively highlights the pitfalls that may occur in diagnostic radiology. Both pitfalls specific to different modalities and techniques and those specific to particular organ systems are described with the help of numerous high-quality illustrations. Recognition of these pitfalls is crucial in helping the practicing radiologist to achieve a more accurate diagnosis.

  10. Diagnostics of Gun Barrel Propellants

    National Research Council Canada - National Science Library

    Lederman, S

    1983-01-01

    A preliminary investigation of the applicability of the spontaneous Raman diagnostic technique to the determination of the temperature of the propellant gases in the vicinity of the muzzle of a 2Omm...

  11. Environmental sensing and combustion diagnostics

    International Nuclear Information System (INIS)

    Santoleri, J.J.

    1991-01-01

    This book contains proceedings of Environmental Sensing and Combustion Diagnostics. Topics covered include: Incineration Systems Applications, Permitting, And Monitoring Overview; Infrared Techniques Applied to Incineration Systems; Continuous Emission Monitors; Analyzers and Sensors for Process Control And Environmental Monitoring

  12. Laser Diagnostics for Reacting Flows

    National Research Council Canada - National Science Library

    Hanson, Ronald K

    2007-01-01

    ... (UV) or infrared (IR) wavelengths. The cw lasers were spectrally narrow, allowing study of innovative diagnostics based on spectral lineshapes, while the pulsed lasers provided intense bursts of photons needed for techniques based on LIF...

  13. Ultraviolet-Visible and Fluorescence Spectroscopy Techniques Are Important Diagnostic Tools during the Progression of Atherosclerosis: Diet Zinc Supplementation Retarded or Delayed Atherosclerosis

    Science.gov (United States)

    Abdelhalim, Mohamed Anwar K.; Moussa, Sherif A. Abdelmottaleb; AL-Mohy, Yanallah Hussain

    2013-01-01

    Background. In this study, we examined whether UV-visible and fluorescence spectroscopy techniques detect the progression of atherosclerosis in serum of rabbits fed on high-cholesterol diet (HCD) and HCD supplemented with zinc (HCD + Zn) compared with the control. Methods. The control rabbits group was fed on 100 g/day of normal diet. The HCD group was fed on Purina Certified Rabbit Chow supplemented with 1.0% cholesterol plus 1.0% olive oil (100 g/day) for the same period. The HCD + Zn group was fed on normal Purina Certified Rabbit Chow plus 1.0% cholesterol and 1.0% olive oil supplemented with 470 ppm Zn for the same feeding period. UV-visible and fluorescence spectroscopy and biochemistry in Rabbit's blood serum and blood hematology were measured in Rabbit's blood. Results. We found that the fluorescent peak of HCD shifted toward UV-visible wavelength compared with the control using fluorescent excitation of serum at 192 nm. In addition, they showed that supplementation of zinc (350 ppm) restored the fluorescent peak closely to the control. By using UV-visible spectroscopy approach, we found that the peak absorbance of HCD (about 280 nm) was higher than that of control and that zinc supplementation seemed to decrease the absorbance. Conclusions. This study demonstrates that ultraviolet-visible and fluorescence spectroscopy techniques can be applied as noninvasive techniques on a sample blood serum for diagnosing or detecting the progression of atherosclerosis. The Zn supplementation to rabbits fed on HCD delays or retards the progression of atherosclerosis. Inducing anemia in rabbits fed on HCD delays the progression of atherosclerosis. PMID:24350281

  14. In-situ fluorimetry: A powerful non-invasive diagnostic technique for natural dyes used in artefacts. Part II. Identification of orcein and indigo in Renaissance tapestries

    Science.gov (United States)

    Clementi, C.; Miliani, C.; Romani, A.; Santamaria, U.; Morresi, F.; Mlynarska, K.; Favaro, G.

    2009-01-01

    In this paper, three Renaissance tapestries depicting scenes painted by Raffaello Sanzio, conserved at the Vatican Museum, were investigated using in-situ UV-Visible fluorimetric measurements. The results show that this technique is suitable for the detection of natural organic colorants used for dyeing the threads woven in these tapestries. The emission signals detected on red-purple colours were assigned to the colorant orcein and those on different nuances of blue and green colours to indigo by comparison with data from reference laboratory samples. The assignments were supported by chromatographic experiments carried out on threads taken from the back side of the tapestry in the same points analysed by spectrofluorimentry.

  15. Diagnostic reproducibility of hydatidiform moles: ancillary techniques (p57 immunohistochemistry and molecular genotyping) improve morphologic diagnosis for both recently trained and experienced gynecologic pathologists.

    Science.gov (United States)

    Gupta, Mamta; Vang, Russell; Yemelyanova, Anna V; Kurman, Robert J; Li, Fanghong Rose; Maambo, Emily C; Murphy, Kathleen M; DeScipio, Cheryl; Thompson, Carol B; Ronnett, Brigitte M

    2012-12-01

    Distinction of hydatidiform moles from nonmolar specimens (NMs) and subclassification of hydatidiform moles as complete hydatidiform mole (CHM) and partial hydatidiform mole (PHM) are important for clinical practice and investigational studies; however, diagnosis based solely on morphology is affected by interobserver variability. Molecular genotyping can distinguish these entities by discerning androgenetic diploidy, diandric triploidy, and biparental diploidy to diagnose CHMs, PHMs, and NMs, respectively. Eighty genotyped cases (27 CHMs, 27 PHMs, 26 NMs) were selected from a series of 200 potentially molar specimens previously diagnosed using p57 immunohistochemistry and genotyping. Cases were classified by 6 pathologists (3 faculty level gynecologic pathologists and 3 fellows) on the basis of morphology, masked to p57 immunostaining and genotyping results, into 1 of 3 categories (CHM, PHM, or NM) during 2 diagnostic rounds; a third round incorporating p57 immunostaining results was also conducted. Consensus diagnoses (those rendered by 2 of 3 pathologists in each group) were also determined. Performance of experienced gynecologic pathologists versus fellow pathologists was compared, using genotyping results as the gold standard. Correct classification of CHMs ranged from 59% to 100%; there were no statistically significant differences in performance of faculty versus fellows in any round (P-values of 0.13, 0.67, and 0.54 for rounds 1 to 3, respectively). Correct classification of PHMs ranged from 26% to 93%, with statistically significantly better performance of faculty versus fellows in each round (P-values of 0.04, <0.01, and <0.01 for rounds 1 to 3, respectively). Correct classification of NMs ranged from 31% to 92%, with statistically significantly better performance of faculty only in round 2 (P-values of 1.0, <0.01, and 0.61 for rounds 1 to 3, respectively). Correct classification of all cases combined ranged from 51% to 75% by morphology and 70% to 80

  16. Vertical vs. transverse sections of scalp biopsy specimens: a pilot study on the comparison of the diagnostic value of two techniques in alopecia.

    Science.gov (United States)

    Özcan, D; Özen, Ö; Seçkin, D

    2011-12-01

    Using both vertical and transverse sections is preferred for histopathological diagnosis of alopecia. However, in cases in which only a single biopsy is taken, it is not clear which type of sectioning is better. To compare the diagnostic value of transverse and vertical sections. In total, 53 patients with alopecia were enrolled in the study. Two biopsies were taken from each patient, and cut into either transverse or vertical sections. The clinical and histopathological findings were evaluated together for the definitive diagnosis. After the study period, a pathologist randomly re-evaluated the sections. We compared the histopathological diagnoses with the definitive diagnoses, and determined the sensitivity and specificity of each method. A definitive diagnosis was made for 47 patients (88.7%). Of these, 30 (63.8%) had noncicatricial and 17 (36.2%) had cicatricial alopecia, and the diagnosis was made by transverse and vertical sections for 43 (91.5%) and 39 (88%), respectively (P > 0.05; sensitivity; 91.5% vs. 82%). All 30 patients with noncicatricial alopecia were diagnosed by transverse sections, and 25 (83.3%) of the 30 were diagnosed with vertical sections (P = 0.05; sensitivity 100% vs. 83.3%). Of the 17 patients with cicatricial alopecia, 13 (76.5%) and 14 (82.4%) patients were diagnosed by transverse and vertical sections, respectively (P > 0.05; sensitivity 76.5% vs. 82.4%). Five patients with lichen planopilaris were diagnosed by vertical sections, and one by transverse sections. There were several limitations to the study: (i) statistical subtype analysis could be performed only for alopecia areata; (ii) no conclusion could be drawn about the interobserver reliability of two sections; and (iii) having the pathologist-blinded study performed retrospectively might have caused a recall bias. If only a single biopsy specimen is available, it may be preferable to have transverse sections in cases of suspected noncicatricial alopecia, and vertical sections in

  17. Diagnostic accuracy of semi-quantitative and quantitative culture techniques for the diagnosis of catheter-related infections in newborns and molecular typing of isolated microorganisms.

    Science.gov (United States)

    Riboli, Danilo Flávio Moraes; Lyra, João César; Silva, Eliane Pessoa; Valadão, Luisa Leite; Bentlin, Maria Regina; Corrente, José Eduardo; Rugolo, Ligia Maria Suppo de Souza; da Cunha, Maria de Lourdes Ribeiro de Souza

    2014-05-22

    Catheter-related bloodstream infections (CR-BSIs) have become the most common cause of healthcare-associated bloodstream infections in neonatal intensive care units (ICUs). Microbiological evidence implicating catheters as the source of bloodstream infection is necessary to establish the diagnosis of CR-BSIs. Semi-quantitative culture is used to determine the presence of microorganisms on the external catheter surface, whereas quantitative culture also isolates microorganisms present inside the catheter. The main objective of this study was to determine the sensitivity and specificity of these two techniques for the diagnosis of CR-BSIs in newborns from a neonatal ICU. In addition, PFGE was used for similarity analysis of the microorganisms isolated from catheters and blood cultures. Semi-quantitative and quantitative methods were used for the culture of catheter tips obtained from newborns. Strains isolated from catheter tips and blood cultures which exhibited the same antimicrobial susceptibility profile were included in the study as positive cases of CR-BSI. PFGE of the microorganisms isolated from catheters and blood cultures was performed for similarity analysis and detection of clones in the ICU. A total of 584 catheter tips from 399 patients seen between November 2005 and June 2012 were analyzed. Twenty-nine cases of CR-BSI were confirmed. Coagulase-negative staphylococci (CoNS) were the most frequently isolated microorganisms, including S. epidermidis as the most prevalent species (65.5%), followed by S. haemolyticus (10.3%), yeasts (10.3%), K. pneumoniae (6.9%), S. aureus (3.4%), and E. coli (3.4%). The sensitivity of the semi-quantitative and quantitative techniques was 72.7% and 59.3%, respectively, and specificity was 95.7% and 94.4%. The diagnosis of CR-BSIs based on PFGE analysis of similarity between strains isolated from catheter tips and blood cultures showed 82.6% sensitivity and 100% specificity. The semi-quantitative culture method showed higher

  18. Revolutionary introduction of RIA/IRMA methodology in medical diagnostics: a study employing the technique for hyperprolactinemia and its correlation with hypothyroidism

    International Nuclear Information System (INIS)

    Tasneem, A.

    2011-01-01

    The aim of the study was to determine the incidence of hyperprolactinemia, its underlying causes and consequences, and to study its correlation with hypothyroidism. The study was carried out on 1365 male and female subjects referred to Centre for Nuclear Medicine Lahore for hormonal estimation. Serum Prolactin and thyroid stimulating hormone (TSH) levels were measured using IRMA kits. Prevalence of hyperprolactinemia turned out to be 4.90%. Menstrual irregularity appeared as a major consequence. The incidence rate was the highest in the age range of 21-27 years. Hypothyroidism in hyperprolactinemic subjects was observed to be 22.7%. i) Immunoradiometric assay is a micro analytical technique which can measure very minute amount of the antigens in the serum. II) Prevalence of hypothyroidism in hyperprolactinemic subjects in our population is promising enough to estimate thyroid hormone levels in hyperprolactinemic patients. (author)

  19. Metabolomics for laboratory diagnostics.

    Science.gov (United States)

    Bujak, Renata; Struck-Lewicka, Wiktoria; Markuszewski, Michał J; Kaliszan, Roman

    2015-09-10

    Metabolomics is an emerging approach in a systems biology field. Due to continuous development in advanced analytical techniques and in bioinformatics, metabolomics has been extensively applied as a novel, holistic diagnostic tool in clinical and biomedical studies. Metabolome's measurement, as a chemical reflection of a current phenotype of a particular biological system, is nowadays frequently implemented to understand pathophysiological processes involved in disease progression as well as to search for new diagnostic or prognostic biomarkers of various organism's disorders. In this review, we discussed the research strategies and analytical platforms commonly applied in the metabolomics studies. The applications of the metabolomics in laboratory diagnostics in the last 5 years were also reviewed according to the type of biological sample used in the metabolome's analysis. We also discussed some limitations and further improvements which should be considered taking in mind potential applications of metabolomic research and practice. Copyright © 2014 Elsevier B.V. All rights reserved.

  20. The EnVision++ system: a new immunohistochemical method for diagnostics and research. Critical comparison with the APAAP, ChemMate, CSA, LABC, and SABC techniques.

    Science.gov (United States)

    Sabattini, E; Bisgaard, K; Ascani, S; Poggi, S; Piccioli, M; Ceccarelli, C; Pieri, F; Fraternali-Orcioni, G; Pileri, S A

    1998-07-01

    To assess a newly developed immunohistochemical detection system, the EnVision++. A large series of differently processed normal and pathological samples and 53 relevant monoclonal antibodies were chosen. A chessboard titration assay was used to compare the results provided by the EnVision++ system with those of the APAAP, CSA, LSAB, SABC, and ChemMate methods, when applied either manually or in a TechMate 500 immunostainer. With the vast majority of the antibodies, EnVision++ allowed two- to fivefold higher dilutions than the APAAP, LSAB, SABC, and ChemMate techniques, the staining intensity and percentage of expected positive cells being the same. With some critical antibodies (such as the anti-CD5), it turned out to be superior in that it achieved consistently reproducible results with differently fixed or overfixed samples. Only the CSA method, which includes tyramide based enhancement, allowed the same dilutions as the EnVision++ system, and in one instance (with the anti-cyclin D1 antibody) represented the gold standard. The EnVision++ is an easy to use system, which avoids the possibility of disturbing endogenous biotin and lowers the cost per test by increasing the dilutions of the primary antibodies. Being a two step procedure, it reduces both the assay time and the workload.

  1. Diagnostic dilemma

    DEFF Research Database (Denmark)

    Feldt-Rasmussen, Ulla; Dobrovolny, Robert; Nazarenko, Irina

    2011-01-01

    Fabry disease, an X-linked lysosomal storage disorder, results from the deficient activity of a-galactosidase A (a-Gal A). In affected males, the clinical diagnosis is confirmed by the markedly decreased a-Gal A activity. However, in female heterozygotes, the a-Gal A activity can range from low t...... on enzyme replacement therapy. Thus, gene dosage analyses can detect large deletions (>50bp) in suspect heterozygotes for X-linked and autosomal dominant diseases that are "sequencing cryptic," resolving molecular diagnostic dilemmas....... to normal due to random X-chromosomal inactivation, and diagnostic confirmation requires identification of the family's a-Gal A gene mutation. In a young female who had occasional acroparesthesias, corneal opacities, and 15 to 50% of the lower limit of normal leukocyte a-Gal A activity, a-Gal A sequencing...... in two expert laboratories did not identify a confirmatory mutation, presenting a diagnostic dilemma. A renal biopsy proved diagnostic and renewed efforts to detect an a-Gal A mutation. Subsequent gene dosage analyses identified a large a-Gal A deletion confirming her heterozygosity, and she was started...

  2. [Patent ductus arteriosus in the dog: a retrospective study of clinical presentation, diagnostics and comparison of interventional techniques in 102 dogs (2003-2011)].

    Science.gov (United States)

    Meijer, M; Beijerink, N J

    2012-06-01

    A left-to-right shunting patent ductus arteriosus (PDA) is a common congenital heart defect in dogs. If it is left uncorrected, life expectancy in most cases is decreased due to the development of left-sided congestive heart failure. The aim of this study was to describe the dogs diagnosed with PDA in the Utrecht University Companion Animal Clinic from 2003 to 2011. The medical records of 102 patients were retrieved, and the clinical presentation and outcome of PDA closure by surgical ligation or transarterial catheter occlusion (TCO) were reviewed. In the TCO group, the result of coiling was compared with the placement of an Amplatz Canine Duct Occluder (ACDO). A predisposition to PDA was found in the German Brak, Stabyhoun, and Schapendoes. Dogs treated with surgical ligation were significantly older and heavier than those treated with TCO; within the TCO group, dogs treated with ACDO were significantly older and heavier The initial success rate (complete disappearance of the audible murmur in a patient that survived the procedure) was not significantly different between the different treatment modalities. Major complications were more common with surgical ligation, but the incidence of minor complications was not significantly different. There was no diference in survival between dogs treated with surgical ligation and dogs treated with TCO. This study shows a previously unreported predisposition to PDA in certain breeds. Both surgical ligation and TCO are suitable techniques for PDA closure, although major complications were more common with surgical ligation. ACDO appears to be the method with the least complications and thus can be considered the safest method.

  3. Mild cognitive impairment. Diagnostic value of different MR techniques; ''Mild cognitive impairment''. Diagnostische Wertigkeit verschiedener MR-Techniken

    Energy Technology Data Exchange (ETDEWEB)

    Hauser, T.; Stieltjes, B.; Essig, M. [Deutsches Krebsforschungszentrum (DKFZ) Heidelberg, Abteilung E010 Radiologie, Heidelberg (Germany); Thomann, P.A. [Zentrum fuer Psychosoziale Medizin, Universitaetsklinikum Heidelberg, AG Strukturelle Bildgebung, Klinik fuer Allgemeine Psychiatrie, Heidelberg (Germany)

    2011-04-15

    In view of an increasingly aging population the prevalence of dementia is also expected to increase rapidly. As well as clinical, neuropsychological and laboratory procedures magnetic resonance imaging (MRI) plays an important role in the early diagnosis of dementia which is important in the precursor stage of mild cognitive impairment (MCI). On the one hand this stage is associated with an increased risk of dementia and on the other hand an early treatment in this stage could attenuate development of the disease. In addition to morphological changes different functional MRI techniques can help in the early diagnosis of dementia and the precursor stages. Moreover, it is important to detect those MCI patients who are at particularly risk for developing dementia. In the differentiation of converters to non-converters initial studies suggest that particularly voxel-based morphometry, MR spectroscopy and diffusion tensor imaging can provide important additional information. (orig.) [German] Angesichts einer immer aelter werdenden Bevoelkerung sind wir mit dem Problem einer zunehmenden Zahl an Patienten mit Demenzerkrankungen konfrontiert. In der Fruehdiagnostik einer Demenz spielen neben klinischen, neuropsychologischen und laborchemischen Untersuchungen nichtinvasive Bildgebungsverfahren wie die MRT eine bedeutende Rolle. Wichtig ist dabei die Fruehdiagnostik einer Demenz bereits im Vorstadium der leichten kognitiven Beeintraechtigung (''mild cognitive impairment'', MCI), da dieses Krankheitsbild mit einem deutlich erhoehten Demenzrisiko einhergeht und durch eine fruehzeitige Therapie der Krankheitsverlauf abgemildert oder deutlich verzoegert werden kann. Neben morphologischen Veraenderungen helfen verschiedene funktionelle MR-Verfahren bei der Fruehdiagnostik einer Demenz. Darueber hinaus ist es von grosser Bedeutung, diejenigen MCI-Patienten zu detektieren, die in besonderem Masse von einer Demenz bedroht sind. Bei der Differenzierung von

  4. Nanobiosensors in diagnostics

    Directory of Open Access Journals (Sweden)

    Alejandro Chamorro-Garcia

    2016-11-01

    Full Text Available Medical diagnosis has been greatly improved thanks to the development of new techniques capable of performing very sensitive detection and quantifying certain parameters. These parameters can be correlated with the presence of specific molecules and their quantity. Unfortunately, these techniques are demanding, expensive, and often complicated. On the other side, progress in other fields of science and technology has contributed to the rapid growth of nanotechnology. Although being an emerging discipline, nanotechnology has raised huge interest and expectations. Most of the enthusiasm comes from new possibilities and properties of nanomaterials. Biosensors (simple, robust, sensitive, cost-effective combined with nanomaterials, also called nanobiosensors, are serving as bridge between advanced detection/diagnostics and daily/routine tests. Here we review some of the latest applications of nanobiosensors in diagnostics field.

  5. Summary from working group on noninterceptive diagnostics

    International Nuclear Information System (INIS)

    Chamberlin, D.D.

    1985-01-01

    The working group for noninterceptive diagnostics spent much of its time comparing diagnostic techniques from different fields and their possible application to high-power injectors. The group included backgrounds from electron beam diagnostics, fusion power diagnostics, cw ion source and transport design, and ion beam of diagnostics. The probability of success for adapting techniques from these different areas is quite difficult to judge, short of a detailed examination of each application. Unexpected flaws or unforeseen noise sources can eliminate an idea that would otherwise appear promising. The report presents several ideas that were discussed, with an indication of those ideas most likely to succeed if implemented

  6. Molecular diagnostics of periodontitis.

    Science.gov (United States)

    Korona-Głowniak, Izabela; Siwiec, Radosław; Berger, Marcin; Malm, Anna; Szymańska, Jolanta

    2017-01-28

    The microorganisms that form dental plaque are the main cause of periodontitis. Their identification and the understanding of the complex relationships and interactions that involve these microorganisms, environmental factors and the host's health status enable improvement in diagnostics and targeted therapy in patients with periodontitis. To this end, molecular diagnostics techniques (both techniques based on the polymerase chain reaction and those involving nucleic acid analysis via hybridization) come increasingly into use. On the basis of a literature review, the following methods are presented: polymerase chain reaction (PCR), real-time polymerase chain reaction (real-time PCR), 16S rRNA-encoding gene sequencing, checkerboard and reverse-capture checkerboard hybridization, microarrays, denaturing gradient gel electrophoresis (DGGE), temperature gradient gel electrophoresis (TGGE), as well as terminal restriction fragment length polymorphism (TRFLP) and next generation sequencing (NGS). The advantages and drawbacks of each method in the examination of periopathogens are indicated. The techniques listed above allow fast detection of even small quantities of pathogen present in diagnostic material and prove particularly useful to detect microorganisms that are difficult or impossible to grow in a laboratory.

  7. Molecular diagnostics of periodontitis

    Directory of Open Access Journals (Sweden)

    Izabela Korona-Głowniak

    2017-01-01

    Full Text Available The microorganisms that form dental plaque are the main cause of periodontitis. Their identification and the understanding of the complex relationships and interactions that involve these microorganisms, environmental factors and the host’s health status enable improvement in diagnostics and targeted therapy in patients with periodontitis. To this end, molecular diagnostics techniques (both techniques based on the polymerase chain reaction and those involving nucleic acid analysis via hybridization come increasingly into use. On the basis of a literature review, the following methods are presented: polymerase chain reaction (PCR, real-time polymerase chain reaction (real-time PCR, 16S rRNA-encoding gene sequencing, checkerboard and reverse-capture checkerboard hybridization, microarrays, denaturing gradient gel electrophoresis (DGGE, temperature gradient gel electrophoresis (TGGE, as well as terminal restriction fragment length polymorphism (TRFLP and next generation sequencing (NGS. The advantages and drawbacks of each method in the examination of periopathogens are indicated. The techniques listed above allow fast detection of even small quantities of pathogen present in diagnostic material and prove particularly useful to detect microorganisms that are difficult or impossible to grow in a laboratory.

  8. Feasibility and Diagnostic Accuracy of Whole Heart Coronary MR Angiography Using Free-Breathing 3D Balanced Turbo-Field-Echo with SENSE and the Half-Fourier Acquisition Technique

    International Nuclear Information System (INIS)

    Kim, Young Jin; Seo, Jae Seung; Choi, Byoung Wook; Choe, Kyu Ok; Jang, Yang Soo; Ko, Young Guk

    2006-01-01

    We wanted to assess the feasibility and diagnostic accuracy of whole heart coronary magnetic resonance angiography (MRA) with using 3D balanced turbo-field-echo (b-TFE) with SENSE and the half-Fourier acquisition technique for identifying stenoses of the coronary artery. Twenty-one patients who underwent both whole heart coronary MRA examinations and conventional catheter coronary angiography examinations were enrolled in the study. The whole heart coronary MRA images were acquired using a navigator gated 3D b-TFE sequence with SENSE and the half-Fourier acquisition technique to reduce the acquisition time. The imaging slab covered the whole heart (80 contiguous slices with a reconstructed slice thickness of 1.5 mm) along the transverse axis. The quality of the images was evaluated by using a 5-point scale (0 - uninterpretable, 1 - poor, 2 - fair, 3 - good, 4 - excellent). Ten coronary segments of the heart were evaluated in each case; the left main coronary artery (LM), and the proximal, middle and distal segments of the left anterior descending (LAD), the left circumflex (LCX) and the right coronary artery (RCA). The diagnostic accuracy of whole heart coronary MRA for detecting significant coronary artery stenosis was determined on the segment-bysegment basis, and it was compared with the results obtained by conventional catheter angiography, which is the gold standard. The mean image quality was 3.7 in the LM, 3.2 in the LAD, 2.5 in the LCX, and 3.3 in the RCA, respectively (the overall image quality was 3.0 ± 0.1). 168 (84%) of the 201 segments had an acceptable image quality (≥ grade 2). The sensitivity, specificity, accuracy, negative predictive value and positive predictive value of the whole heart coronary MRA images for detecting significant stenosis were 81.3%, 92.1%, 91.1%, 97.9%, and 52.0%, respectively. The mean coronary MRA acquisition time was 9 min 22 sec (± 125 sec). Whole heart coronary MRA is a feasible technique, and it has good potential to

  9. Diagnostic techniques applied in geostatistics for agricultural data analysis Técnicas de diagnóstico utilizadas em geoestatística para análise de dados agrícolas

    Directory of Open Access Journals (Sweden)

    Joelmir André Borssoi

    2009-12-01

    Full Text Available The structural modeling of spatial dependence, using a geostatistical approach, is an indispensable tool to determine parameters that define this structure, applied on interpolation of values at unsampled points by kriging techniques. However, the estimation of parameters can be greatly affected by the presence of atypical observations in sampled data. The purpose of this study was to use diagnostic techniques in Gaussian spatial linear models in geostatistics to evaluate the sensitivity of maximum likelihood and restrict maximum likelihood estimators to small perturbations in these data. For this purpose, studies with simulated and experimental data were conducted. Results with simulated data showed that the diagnostic techniques were efficient to identify the perturbation in data. The results with real data indicated that atypical values among the sampled data may have a strong influence on thematic maps, thus changing the spatial dependence structure. The application of diagnostic techniques should be part of any geostatistical analysis, to ensure a better quality of the information from thematic maps.A modelagem da estrutura de dependência espacial pela abordagem da geoestatística é de fundamental importância para a definição de parâmetros que definem essa estrutura e que são utilizados na interpolação de valores em locais não amostrados, pela técnica de krigagem. Entretanto, a estimação de parâmetros pode ser muito alterada pela presença de observações atípicas nos dados amostrados. O desenvolvimento deste trabalho teve por objetivo utilizar técnicas de diagnóstico em modelos espaciais lineares gaussianos, empregados em geoestatística, para avaliar a sensibilidade dos estimadores de máxima verossimilhança e máxima verossimilhança restrita a pequenas perturbações nos dados. Foram realizados estudos de dados simulados e experimentais. O estudo com dados simulados mostrou que as técnicas de diagnóstico foram

  10. Informed decision-making before changing to RDT: a comparison of microscopy, rapid diagnostic test and molecular techniques for the diagnosis and identification of malaria parasites in Kassala, eastern Sudan.

    Science.gov (United States)

    Osman, Mamoun M M; Nour, Bakri Y M; Sedig, Mohamed F; De Bes, Laura; Babikir, Adil M; Mohamedani, Ahmed A; Mens, Petra F

    2010-12-01

    Rapid diagnostic tests (RDTs) are promoted for the diagnosis of malaria in many countries. The question arises whether laboratories where the current method of diagnosis is microscopy should also switch to RDT. This problem was studied in Kassala, Sudan where the issue of switching to RDT is under discussion. Two hundred and three blood samples were collected from febrile patients suspected of having malaria. These were subsequently analysed with microscopy, RDT (SD Bioline P.f/P.v) and PCR for the detection and identification of Plasmodium parasites. Malaria parasites were detected in 36 blood samples when examined microscopically, 54 (26.6%) samples were found positive for malaria parasites by RDT, and 44 samples were positive by PCR. Further analysis showed that the RDT used in our study resulted in a relatively high number of false positive samples. When microscopy was compared with PCR, an agreement of 96.1% and k = 0.88 (sensitivity 85.7% and specificity 100%) was found. However, when RDT was compared with PCR, an agreement of only 81.2 and k = 0.48 (sensitivity 69% and specificity 84%) was found. PCR has proven to be one of the most specific and sensitive diagnostic methods, particularly for malaria cases with low parasitaemia. However, this technique has limitations in its routine use under resource-limited conditions, such as our study location. At present, based on these results, microscopy remains the best option for routine diagnosis of malaria in Kassala, eastern Sudan. © 2010 Blackwell Publishing Ltd.

  11. Diagnostics for induction accelerators

    International Nuclear Information System (INIS)

    Fessenden, T.J.

    1996-04-01

    The induction accelerator was conceived by N. C. Christofilos and first realized as the Astron accelerator that operated at LLNL from the early 1960's to the end of 1975. This accelerator generated electron beams at energies near 6 MeV with typical currents of 600 Amperes in 400 ns pulses. The Advanced Test Accelerator (ATA) built at Livermore's Site 300 produced 10,000 Ampere beams with pulse widths of 70 ns at energies approaching 50 MeV. Several other electron and ion induction accelerators have been fabricated at LLNL and LBNL. This paper reviews the principal diagnostics developed through efforts by scientists at both laboratories for measuring the current, position, energy, and emittance of beams generated by these high current, short pulse accelerators. Many of these diagnostics are closely related to those developed for other accelerators. However, the very fast and intense current pulses often require special diagnostic techniques and considerations. The physics and design of the more unique diagnostics developed for electron induction accelerators are presented and discussed in detail

  12. Diagnostics for induction accelerators

    International Nuclear Information System (INIS)

    Fessenden, T.J.

    1997-01-01

    The induction accelerator was conceived by N. C. Christofilos and first realized as the Astron accelerator that operated at Lawrence Livermore National Laboratory (LLNL) from the early 1960s to the end of 1975. This accelerator generated electron beams at energies near 6 MeV with typical currents of 600 Amperes in 400-ns pulses. The Advanced Test Accelerator (ATA) built at Livermore close-quote s Site 300 produced 10,000-Ampere beams with pulse widths of 70 ns at energies approaching 50 MeV. Several other electron and ion induction accelerators have been fabricated at LLNL and Lawrence Berkeley National Laboratory (LBNL). This paper reviews the principal diagnostics developed through efforts by scientists at both laboratories for measuring the current, position, energy, and emittance of beams generated by these high-current, short-pulse accelerators. Many of these diagnostics are closely related to those developed for other accelerators. However, the very fast and intense current pulses often require special diagnostic techniques and considerations. The physics and design of the more unique diagnostics developed for electron induction accelerators are presented and discussed in detail. copyright 1997 American Institute of Physics

  13. Gonad shielding in diagnostic radiology

    International Nuclear Information System (INIS)

    Anon.

    1975-01-01

    The use of gonad shielding is an important radiation protection technique, intended to reduce unnecessary x-ray exposure of the gonads of patients from diagnostic x-ray procedures. The types of gonad shields in use are discussed as are the types of diagnostic examinations that should include gonad shielding. It was found that when properly used, most shields provided substantial gonad dose reductions

  14. Screening diagnostic program breast cancer

    International Nuclear Information System (INIS)

    Portnoj, L.M.; Zhakova, I.I.; Budnikova, N.V.; Rukhlyadko, E.D.

    1995-01-01

    The authors propose their screening program for detection of breast cancer. It includes the entire complex of present-day screening diagnostic methods, starting from an original system for the formation of groups at risk of breast cancer and completed by the direct diagnostic model of detection of the condition, oriented at a differentiated approach to the use of mammographic techniques. The proposed organizational and methodologic screening measures are both economic and diagnostically effective, thus meeting the principal requirements to screening programs. Screening of 8541 risk-groups patients helped detect 867 nodular formations, 244 of which were cancer and 623 benign formations. 8 refs., 3 figs.,

  15. Applications of Molecular Diagnostic Techniques for Infectious ...

    African Journals Online (AJOL)

    That outcome, if accurate, would help the clinician in disease management, or the epidemiologist in identifying trends of diseases or the administrator in policy and decision making. Traditionally, infectious disease diagnosis involves identifying the causative agents of infectious diseases through the direct examination, ...

  16. Thyroid diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Scriba, P C; Boerner, W; Emrich, S; Gutekunst, R; Herrmann, J; Horn, K; Klett, M; Krueskemper, H L; Pfannenstiel, P; Pickardt, C R

    1985-03-01

    None of the in-vitro and in-vivo methods listed permits on unambiguous diagnosis when applied alone, owing to the fact that similar or even identical findings are obtained for various individual parameters in different thyroid diseases. Further, especially the in-vitro tests are also subject to extrathyroidal effects which may mask the typical findings. The limited and varying specificity and sensitivity of the tests applied, as well as the falsification of results caused by the patients' idiosyncracies and the methodology, make it necessary to interpret and evaluate the in-vivo and in-vitro findings only if the clinical situation (anamnesis and physical examination) is known. For maximum diagnostic quality of the tests, the initial probability of the assumed type of thyroid disease must be increased (formulation of the clinical problem). The concepts of exclusion diagnosis and identification must be distinguished as well as the diagnosis of functional disturbances on the one hand and of thyroid diseases on the other. Both of this requires a qualified, specific and detailed anamnesis and examination procedure, and the clinical examination remains the obligatory basis of clinical diagnostics. In case of inexplicable discrepancies between the clinical manifestations and the findings obtained with specific methods, or between the findings obtained with a specific method, the patient should be referred to an expert institution, or the expert institution should be consulted.

  17. Thyroid diagnostics

    International Nuclear Information System (INIS)

    Scriba, P.C.; Boerner, W.; Emrich, S.; Gutekunst, R.; Herrmann, J.; Horn, K.; Klett, M.; Krueskemper, H.L.; Pfannenstiel, P.; Pickardt, C.R.; Reiners, C.; Reinwein, D.; Schleusener, H.

    1985-01-01

    None of the in-vitro and in-vivo methods listed permits on unambiguous diagnosis when applied alone, owing to the fact that similar or even identical findings are obtained for various individual parameters in different thyroid diseases. Further, especially the in-vitro tests are also subject to extrathyroidal effects which may mask the typical findings. The limited and varying specificity and sensitivity of the tests applied, as well as the falsification of results caused by the patients' idiosyncracies and the methodology, make it necessary to interpret and evaluate the in-vivo and in-vitro findings only if the clinical situation (anamnesis and physical examination) is known. For maximum diagnostic quality of the tests, the initial probability of the assumed type of thyroid disease must be increased (formulation of the clinical problem). The concepts of exclusion diagnosis and identification must be distinguished as well as the diagnosis of functional disturbances on the one hand and of thyroid diseases on the other. Both of this requires a qualified, specific and detailed anamnesis and examination procedure, and the clinical examination remains the obligatory basis of clinical diagnostics. In case of inexplicable discrepancies between the clinical manifestations and the findings obtained with specific methods, or between the findings obtained with a specific method, the patient should be referred to an expert institution, or the expert institution should be consulted. (orig./MG) [de

  18. Ambient diagnostics

    CERN Document Server

    Cai, Yang

    2014-01-01

    Part I. FundamentalsIntroductionWhat is Ambient Diagnostics?Diagnostic ModelsMultimedia IntelligenceCrowd SourcingSoft SensorsScience of SimplicityPersonal DiagnosesBasic AlgorithmsBasic ToolsSummaryProblemsTransformationEarly Discoveries of Heartbeat PatternsTransforms, Features, and AttributesSequential FeaturesSpatiotemporal FeaturesShape FeaturesImagery FeaturesFrequency Domain FeaturesMulti-Resolution FeaturesSummaryProblemsPattern RecognitionSimilarities and DistancesClustering MethodsClassification MethodsClassifier Accuracy MeasuresSummaryProblemsPart II. Multimedia IntelligenceSound RecognitionMicrophone AppsModern Acoustic Transducers (Microphones)Frequency Response CharacteristicsDigital Audio File FormatsHeart Sound SensingLung Sound SensingSnore MeterSpectrogram (STFT)Ambient Sound AnalysisSound RecognitionRecognizing Asthma SoundPeak ShiftFeature CompressionRegroupingNoise IssuesFuture ApplicationsSummaryProblemsColor SensorsColor SensingHuman Color VisionColor SensorsColor Matching ExperimentsC...

  19. CT guided diagnostic foot injections

    International Nuclear Information System (INIS)

    Saifuddin, A.; Abdus-Samee, M.; Mann, C.; Singh, D.; Angel, J.C.

    2005-01-01

    AIM: To describe a CT technique for guiding diagnostic and therapeutic injections in the hind- and mid-foot. MATERIALS AND METHODS: Over a period of 50 months, 28 individuals were referred for diagnostic and therapeutic hind- and mid-foot injections before possible arthrodesis. A CT technique was developed that allowed entry into the various joints using a vertical approach. Numbers of joints injected were as follows: posterior subtalar, 21; talonavicular, 4; calcaneonavicular, calcaneocuboid, navicular-cuneiform and 5th metatarsocuboid joints, 1 each. RESULTS: All injections but one were technically successful. Significant relief of symptoms was noted by 16 participants, whereas for 9 there was no improvement and for 3 a partial response was achieved. CONCLUSION: CT is a simple and safe alternative to fluoroscopy for guiding diagnostic and therapeutic foot injections, and may be the technique of choice in cases of disordered anatomy

  20. Inertial confinement fusion diagnostics

    International Nuclear Information System (INIS)

    Coleman, L.W.

    1986-10-01

    The concept and goals of ICF will be briefly reviewed and the new 100 kJ class Nova laser facility will be described. Experimental results obtained to date with Nova will be summarized, and the discussions of diagnostics will use examples on the present capabilities of Nova and new developments that are underway. The classes of diagnostic systems to be discussed fall into three basic categories: optical, x-ray, and particle. Examples of highly space resolved, time resolved, and spectrally resolved techniques as well as schemes involving combinations of these capabilities will be presented. A brief summary of the sophisticated acquisition and analysis system in use for Nova data will be provided

  1. Diagnostic radiation risks

    Energy Technology Data Exchange (ETDEWEB)

    Sherwood, T [Addenbrooke' s Hospital, Cambridge (UK)

    1980-04-01

    A brief discussion on diagnostic radiation risks is given. First some fundamental facts on the concepts and units of radiation measurement are clarified. Medical diagnostic radiation doses are also compared to the radiation doses received annually by man from natural background radiation. The controversy concerning the '10-day rule' in X-raying women of child-bearing age is discussed; it would appear that the risk of malformation in an unborn child due to X-radiation is very much less than the natural level of risk of malformation. The differences in the radiographic techniques and thus the different X-ray doses needed to make adequate X-ray images of different parts of the body are considered. The radiation burden of nuclear medicine investigations compared to X-ray procedures is also discussed. Finally, the problems of using volunteers in radiation research are aired.

  2. Diagnostics and structure

    International Nuclear Information System (INIS)

    Vial, J.C.

    1986-01-01

    The structure of prominences and the diagnostic techniques used to evaluate their physical parameters are discussed. These include electron temperature, various densities (n sub p, n sub e, n sub l), ionization degree, velocities, and magnetic field vector. UV and radio measurements have already evidenced the existence of different temperature regions, corresponding to different geometrical locations, e.g., the so called Prominence-Corona (P-C) interface. Velocity measurements are important for considering formation and mass balance of prominences but there are conflicting velocity measurements which have led to the basic question: what structure is actually observed at a given wavelength; what averaging is performed within the projected slit area during the exposure time? In optically thick lines, the question of the formation region of the radiation along the line of sight is also not a trivial one. The same is true for low resolution measurements of the magnetic field. Coupling diagnostics with structure is now a general preoccupation

  3. FEL components and diagnostics

    International Nuclear Information System (INIS)

    Carr, R.

    1997-01-01

    FEL hardware includes undulators, alignment systems, electron beam diagnostics, and mechanical and vacuum systems. While most FEL close-quote s employ conventional undulators, there is some interest in novel types, particularly where conventional designs cannot be used, as at very short periods and high fields. For these areas, superconducting technology is indicated. The most serious issue facing long FEL undulators is that of alignment; mechanical techniques may not be accurate enough, and beam-based strategies must be considered. To maintain alignment and control the electron trajectory, beam position monitors with micron precision are required. Beam size monitors are also required to assure control of emittance. The talks given in the working group sessions touch on undulators, alignment, and electron beam diagnostics, and they are summarized here. copyright 1997 American Institute of Physics

  4. Diagnostic accuracy of organ electrodermal diagnostics | Szopinski ...

    African Journals Online (AJOL)

    Objective. To estimate the diagnostic accuracy as well as the scope of utilisation of a new bio-electronic method of organ diagnostics. Design. Double-blind comparative study of the diagnostic results obtained by means of organ electrodermal diagnostics (OED) and clinical diagnoses, as a criterion standard. Setting.

  5. SNS Diagnostics

    International Nuclear Information System (INIS)

    Shea, T.J.; Cameron, P.; Doolittle, L.; Power, J.

    2000-01-01

    The Spallation Neutron Source (SNS) Project is a collaborative effort to build the next generation neutron science facility at Oak Ridge, TN. The facility will deliver a 2 MW proton beam to a liquid mercury target. Neutrons from this target will be moderated and sent to several state-of-the-art instruments. Six national laboratories are involved in SNS construction. Berkeley (LBNL) will build the front end that produces a 2.5 MeV, 52 mA H-beam. Los Alamos (LANL) is responsible for the 1 GeV linac with a superconducting section provided by Thomas Jefferson (JLab). Brookhaven (BNL) is building the transfer lines and accumulator ring. Oak Ridge (ORNL) and Argonne (ANL) have responsibility for the target and instruments. All activities are coordinated by the SNS project office at Oak Ridge. The high beam power, a desired availability of 95%, and an aggressive commissioning schedule lead to some interesting challenges in beam diagnostics

  6. Optical diagnostics of intermittent flows

    DEFF Research Database (Denmark)

    Okulov, V.L.; Naumov, I.V.; Sørensen, Jens Nørkær

    2007-01-01

    The efficiency of combined use of different optical techniques for flow diagnostics is demonstrated with the practically important case of intense swirling flows. It is shown that, when applied separately, commonly used optical measuring techniques, such as laser Doppler anemometry and particle...... is for the first time applied for diagnostics of the flow pattern in a closed cylinder with a rotating end face with the aim of studying the changeover from the steady axisymmetric to unsteady asymmetric flow over a wide range of flow parameters. It is found that such a transition is notable for azimuthal...

  7. a partir de su respuesta en el dominio de la frecuencia. Estado mundial del arte. Parte I; Techniques of Diagnostic in Transformers from their Answer in Frequency Domain. World State of the Art. Part I

    Directory of Open Access Journals (Sweden)

    Orestes Hernández Areu

    2011-02-01

    Full Text Available Cada día cobra más importancia en el tema de los transformadores de potencia, la necesidad del diagnósticode los mismos y la detección de averías o anomalías que pudieran surgir durante su explotación. Existenmétodos para el diagnóstico de estos equipos, a través del llamado: Análisis de la respuesta en la frecuencia(FRA; en Cuba, aún no se ha introducido ninguna técnica de esta naturaleza, pero se comienzan ainvestigar sus potencialidades y posibilidades de introducción. Inicialmente se ha realizado un estudio delas fuentes que abordan este tema. En este artículo, se presenta la primera parte de un análisis que se harealizado del estado mundial del arte sobre las técnicas de diagnóstico en transformadores a partir de surespuesta  en  el  dominio  de  la  frecuencia,  específicamente  sobre  los  métodos  de  diagnóstico  detransformadores mediante el análisis de su respuesta en frecuencia, empleando la transformada rápida defourier (FFT.  Every day it gets paid more importance in the topic of the power transformers, the necessity of the diagnosisand the failures or anomalies detection than they could arise during their exploitation.  Methods exist for thediagnosis of these equipments, through the called frequency response analysis (FRA; in Cuba, techniquesof this nature has not still been introduced, but begins to investigate its potentialities and introductionpossibilities. As beginning of this investigation process, has been carried out a study of the sources thatapproach this topic. In this article, is presented the first part of an analysis that has been carried out aboutthe state of the world art on techniques of diagnostic of transformers from its frequency domain response.This part is about those methods of diagnostic of transformers by means of the analysis of their frequencyresponse, using the fast fourier transformed (FFT.

  8. Planetary Transmission Diagnostics

    Science.gov (United States)

    Lewicki, David G. (Technical Monitor); Samuel, Paul D.; Conroy, Joseph K.; Pines, Darryll J.

    2004-01-01

    This report presents a methodology for detecting and diagnosing gear faults in the planetary stage of a helicopter transmission. This diagnostic technique is based on the constrained adaptive lifting algorithm. The lifting scheme, developed by Wim Sweldens of Bell Labs, is a time domain, prediction-error realization of the wavelet transform that allows for greater flexibility in the construction of wavelet bases. Classic lifting analyzes a given signal using wavelets derived from a single fundamental basis function. A number of researchers have proposed techniques for adding adaptivity to the lifting scheme, allowing the transform to choose from a set of fundamental bases the basis that best fits the signal. This characteristic is desirable for gear diagnostics as it allows the technique to tailor itself to a specific transmission by selecting a set of wavelets that best represent vibration signals obtained while the gearbox is operating under healthy-state conditions. However, constraints on certain basis characteristics are necessary to enhance the detection of local wave-form changes caused by certain types of gear damage. The proposed methodology analyzes individual tooth-mesh waveforms from a healthy-state gearbox vibration signal that was generated using the vibration separation (synchronous signal-averaging) algorithm. Each waveform is separated into analysis domains using zeros of its slope and curvature. The bases selected in each analysis domain are chosen to minimize the prediction error, and constrained to have the same-sign local slope and curvature as the original signal. The resulting set of bases is used to analyze future-state vibration signals and the lifting prediction error is inspected. The constraints allow the transform to effectively adapt to global amplitude changes, yielding small prediction errors. However, local wave-form changes associated with certain types of gear damage are poorly adapted, causing a significant change in the

  9. Towards diagnostics for a fusion reactor

    International Nuclear Information System (INIS)

    Costley, A. E.

    2009-01-01

    The requirements for measurements on modern tokamak fusion plasmas are outlined, and the techniques and systems used to make the measurements, usually referred to as 'diagnostics', are introduced. The basics of three particular diagnostics - magnetics, neutron systems and a laser based optical system - are outlined as examples of modern diagnostic systems, and the implementation of these diagnostics on a current tokamak (JET) are described. The next major step in magnetic confinement fusion is the construction and operation of the International Thermonuclear Experimental Reactor (ITER), which is a joint project of China, Europe, Japan, India, Korea, the Russian Federation, and the United States. Construction has begun in Cadarache, France. It is expected that ITER will operate at the 500 MW level. Because of the harsh environment in the vacuum vessel where many diagnostic components are located, the development of diagnostics for ITER is a major challenge - arguably the most difficult challenge ever undertaken in the field of diagnostics. The main elements in the diagnostic step are outlined using the three chosen techniques as examples. Finally, the step beyond ITER to a demonstration reactor, DEMO, that is expected to produce several GWs of fusion power is considered and the impact on diagnostics outlined. It is shown that the applicability and development steps needed for the individual diagnostics techniques will differ. The challenges for DEMO diagnostics are substantial and a dedicated effort should be made to find and develop new techniques, and especially techniques appropriate to the DEMO environment. It is argued that the limitations and difficulties in diagnostics should be a consideration in the optimization and designs of DEMO. (author)

  10. Microfluidic technology for molecular diagnostics.

    Science.gov (United States)

    Robinson, Tom; Dittrich, Petra S

    2013-01-01

    Molecular diagnostics have helped to improve the lives of millions of patients worldwide by allowing clinicians to diagnose patients earlier as well as providing better ongoing therapies. Point-of-care (POC) testing can bring these laboratory-based techniques to the patient in a home setting or to remote settings in the developing world. However, despite substantial progress in the field, there still remain many challenges. Progress in molecular diagnostics has benefitted greatly from microfluidic technology. This chapter aims to summarise the more recent advances in microfluidic-based molecular diagnostics. Sections include an introduction to microfluidic technology, the challenges of molecular diagnostics, how microfluidic advances are working to solve these issues, some alternative design approaches, and detection within these systems.

  11. Calibration issues for neutron diagnostics

    International Nuclear Information System (INIS)

    Sadler, G.J.; Adams, J.M.; Barnes, C.W.

    1997-10-01

    In order for ITER to meet its operational and programmatic goals, it will be necessary to measure a wide range of plasma parameters. Some of the required parameters e.g., neutron yield, fusion power and power density, ion temperature profile in the core plasma, and characteristics of confined and escaping alpha particle populations are best measured by fusion product diagnostic techniques. To make these measurements, ITER will have dedicated diagnostic systems, including radial and vertical neutron cameras, neutron and gamma ray spectrometers, internal and external fission chambers, a neutron activation system, and diagnostics for confined and escaping alpha particles. Engineering integration of many of these systems is in progress, and other systems are under investigation. This paper summarizes the present state of design of fusion product diagnostic systems for ITER and discusses expected measurement capability

  12. Diagnostic thoracoscopy

    Directory of Open Access Journals (Sweden)

    Plavec Goran

    2002-01-01

    Full Text Available Diagnostic thoracoscopy in patients with pleural effusion of unclear origin mostly provides the correct diagnosis. Results from published reports of previous researches are not uniform. In 47 male and 20 female patients with pleural effusion of unknown etiology, after receiving negative results obtained from cytological finding of pleural effusion and percutaneous needle biopsy, thoracoscopy with biopsy of one or both pleurae was performed. Procedure was done in local anesthesia using Stortz rigid thoracoscope. In 37 patients with malignant disease (primary or metastatic diagnosis was confirmed histopathologically in 31 patient (81.12%. In 27 patients with inflammatory pleural disease diagnosis was confirmed histopathologically in 22 patients (81.4%. Among 11 patients with specific pleural effusions, tuberculosis was confirmed in 10 (90.91%. Normal finding in cases of spontaneous pneumothorax and pulmonary embolism was taken as a positive result. Total number of positive findings was 55 (82.10%. In one patient, the third spontaneous pneumothorax was the indication for thoracoscopy, and after numerous bullae were seen during the procedure, talcum powder pleurodesis was done. In four patients low intensity subcutaneous emphysema occurred one day after thoracoscopy. It can be concluded that thoracoscopy in local anesthesia out of the operating room is good and practical method for solving the unclear pleural effusions, with neglectable rate of complications.

  13. Mitigation diagnostics

    International Nuclear Information System (INIS)

    Hall, S.T.

    1990-01-01

    This paper reports that experience in the remediation of schools and other large buildings has shown the importance of the effects of both the location of geologic sources and HVAC-induced distribution of indoor radon. In general, elevated radon in areas of schools with evenly distributed HVAC pressures are correlated with maximum soil radon emanations. However, strong or unequal HVAC effects can redistribute indoor radon to areas away from the direct source. Effective remediation required a complete understanding of both contributions. In some schools, highest indoor radon levels were located near large return ducts and were attributed to proximity to negative HVAC pressure. Successful sub-slab depressurization systems were installed, however, in rooms with lower indoor but greatest sub-slab radon levels, closest to the source. This shows the inadequacy of using indoor radon levels alone as a basis for remediation. Wings of two other schools with radon problems have equivalent window fan coil units in rooms of equal size and no central HVAC system. Highest indoor radon levels correlated well with highest sub-slab radon levels due to the equivalent effects of the window units. Diagnostic tests in other schools have revealed: blockwall radon transport to upper floors; high blockwall radon adjacent to sub-slab sources; and elevated indoor radon over crawlspace being drawn upward by HVAC-induced negative pressure, determined from indoor to outdoor micromanometer measurements

  14. Recent developments in the techniques of IMAG processing and diagnostic imaging for the cultural heritage; Recenti sviluppi nelle metodologie di elaborazione di immagini e di imaging diagnostico per i beni culturali

    Energy Technology Data Exchange (ETDEWEB)

    Maino, G. [ENEA, Divisione Fisica Applicata, Centro Ricerche E. Clementel, Bologna (Italy); Bonifazzi, C. [Ferrara Univ., Ferrara (Italy). Dipt. di Scienze Biomediche; Sabia, E. [ENEA, Tecnologie Ingegneria e Servizi Ambientali, Centro Ricerche Portici, Naples (Italy)

    2000-07-01

    In this report, the contributions presented to the mini symposium on Recent developments in the techniques of image processing and diagnostic imaging for the cultural heritage are collected. The symposium has been organized within the framework of the V National Congress of SIMAI Italian Society for Applied and Industrial Mathematics (SIMAI 2000), held in Ischia from June 5 to 9, 2000, and shows the main scientific results obtained relevant to the research activities carried out in the frame of sub project 3 of research project GIANO (Advanced Graphics for the National cultural heritage and Employment), jointly funded by MURST (Ministry of University, Scientific and Technological Research) EC (law 488/92). The GIANO-ENEA project contributed, together with CRS4, GNIM-IndAM, Ministero degli Affari Esteri and ST-Microelectronics, to the organization of SIMAI 2000. [Italian] In questo rapporto sono raccolti i contributi presentati al minisimposio su Recenti sviluppi nelle metodologie di elaborazione di immagini e di imaging diagnostico per i beni culturali, organizzato nell'ambito del 5. Congresso Nazionale della SIMAI Societa' Italiana di Matematica Applicata e Industriale (SIMAI 2000), svoltosi a Ischia dal 5 al 9 giugno 2000. Il simposio illustra i principali risultati scientifici ottenuti nel quadro delle attivita' di ricerca del sottoprogetto 3 del piano nazionale GIANO (Grafica Innovativa per il patrimonio Artistico Nazionale e per l'Occupazione giovanile), finanziato dal MURST e dall'UE (legge 488/92). Il progetto GIANO-ENEA ha contribuito, insieme con CRS4, GNIM-IndAM, Ministero degli Affari Esteri e ST-Microelectronics, alla realizzazione di SIMAI 2000.

  15. Far infrared fusion plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Luhmann, N.C. Jr.; Peebles, W.A.

    1990-01-01

    Over the last several years, reflectometry has grown in importance as a diagnostic for both steady-state density Profiles as well as for the investigation of density fluctuations and turbulence. As a diagnostic for density profile measurement, it is generally believed to be well understood in the tokamak environment. However, its use as a fluctuation diagnostic is hampered by a lack of quantitative experimental understanding of its wavenumber sensitivity and spatial resolution. Several researchers, have theoretically investigated these questions. However, prior to the UCLA laboratory investigation, no group has experimentally investigated these questions. Because of the reflectometer's importance to the world effort in understanding plasma turbulence and transport, UCLA has, over the last year, made its primary Task IIIA effort the resolution of these questions. UCLA has taken the lead in a quantitative experimental understanding of reflectometer data as applied to the measurement of density fluctuations. In addition to this, work has proceeded on the design, construction, and installation of a reflectometer system on UCLA's CCT tokamak. This effort will allow a comparison between the improved confinement regimes (H-mode) observed on both the DIII-D and CCT machines with the goal of achieving a physics understanding of the phenomena. Preliminary investigation of a new diagnostic technique to measure density profiles as a function of time has been initiated at UCLA. The technique promises to be a valuable addition to the range of available plasma diagnostics. Work on advanced holographic reflectometry technique as applied to fluctuation diagnostics has awaited a better understanding of the reflectometer signal itself as discussed above. Efforts to ensure the transfer of the diagnostic developments have continued with particular attention devoted to the preliminary design of a multichannel FIR interferometer for MST.

  16. Radiation levels in nuclear diagnostic examinations

    International Nuclear Information System (INIS)

    Vermeulen, A.M.T.I.

    1987-01-01

    To estimate the risks for a pregnant radiological worker, radiation level measurements are executed for common nuclear diagnostic techniques. These measurements are combined with the time which the radiologic worker is present during the performance of the diagnostic techniques. It is concluded that a radiologic worker is receiving less than 5 mSv during pregnancy. This is the case with in vivo determination in a department of nuclear medicine with common diagnostic techniques. Reduction of radiation doses during pregnancy is possible by reduction of heart function examinations, skeletal examinations and brain scans. 1 figure; 13 tabs

  17. Integrated Artificial Intelligence Approaches for Disease Diagnostics.

    Science.gov (United States)

    Vashistha, Rajat; Chhabra, Deepak; Shukla, Pratyoosh

    2018-06-01

    Mechanocomputational techniques in conjunction with artificial intelligence (AI) are revolutionizing the interpretations of the crucial information from the medical data and converting it into optimized and organized information for diagnostics. It is possible due to valuable perfection in artificial intelligence, computer aided diagnostics, virtual assistant, robotic surgery, augmented reality and genome editing (based on AI) technologies. Such techniques are serving as the products for diagnosing emerging microbial or non microbial diseases. This article represents a combinatory approach of using such approaches and providing therapeutic solutions towards utilizing these techniques in disease diagnostics.

  18. Gonad shielding in diagnostic radiology

    International Nuclear Information System (INIS)

    1975-06-01

    The use of gonad shielding is an important radiation protection technique, intended to reduce unnecessary x-ray exposure of the gonads of patients from diagnostic x-ray procedures. This pamphlet will provide physicians and radiologic technologists with information which will aid their appropriate use of gonad shielding

  19. MTX [Microwave Tokamak Experiment] plasma diagnostic system

    International Nuclear Information System (INIS)

    Rice, B.W.; Hooper, E.B.; Brooksby, C.A.

    1987-01-01

    In this paper, a general overview of the MTX plasma diagnostics system is given. This includes a description of the MTX machine configuration and the overall facility layout. The data acquisition system and techniques for diagnostic signal transmission are also discussed. In addition, the diagnostic instruments planned for both an initial ohmic-heating set and a second FEL-heating set are described. The expected range of plasma parameters along with the planned plasma measurements will be reviewed. 7 refs., 5 figs

  20. Laser fusion diagnostics

    International Nuclear Information System (INIS)

    Coleman, L.W.

    1978-01-01

    The current status of the capability of laser fusion diagnostics is reviewed. Optical and infrared streak cameras provide one time resolution measurement capability of less than 10 ps, while x-ray streak cameras provide 15 ps time resolution in the range of about 1--30 keV presently. Time integrated spatial resolutions of 1 μm are provided with a variety of optical techniques. Ultraviolet holographic interferometry has measured electron densities above 10 21 cm -3 with 1 μm spatial resolution and 15 ps temporal resolution. X-ray microscopes provide 3 μm time integrated resolution and the x-ray streak pinhole camera has 6 μm spatial resolution. Development of the framing camera has thus far provided 50 μm spatial resolution with 125 ps frame duration and the third order reconstruction of zone plate images has provided 3 μm resolutions for alpha particles. Time integrated measurements of x-rays span the range shown. Finally, the new Shiva neutron spectrometer increases the energy resolution capability of that technique to 25 keV for 14-MeV neutrons. These combined capabilities provide a unique set of diagnostics for the detailed measurement of the interaction of laser light with targets and a subsequent performance of those targets

  1. Lectures in plasma diagnostics

    International Nuclear Information System (INIS)

    Hutchinson, I.H.

    1990-06-01

    This paper discusses the following topics on plasma diagnostics: Electric probes in flowing and magnetized plasmas; Electron cyclotron emission absorption; Magnetic diagnostics; Spectroscopy; and Thomson Scattering

  2. Diagnostic criteria in MR neurography

    International Nuclear Information System (INIS)

    Baeumer, P.

    2017-01-01

    Peripheral neuropathies are frequent and can mostly be correctly diagnosed by clinical examination and electrophysiology; however, diagnostically difficult cases are sometimes encountered especially with respect to precise localization of nerve lesions. Imaging of the peripheral nervous system has been shown to provide additional useful diagnostic information. In addition to the more widely available nerve sonography, magnetic resonance neurography (MRN) is the method of choice in diagnostically complex cases. The most important pulse sequence is a T2-weighted fat-saturated pulse sequence with high in-plane resolution and detects increased T2-weighted signals of nerve fascicles as a highly sensitive sign for nerve lesions. Further established diagnostic criteria are nerve caliber and, less commonly used, contrast agent uptake. The spatial pattern of nerve lesions aids in the diagnostic classification of neuropathies. Functional imaging techniques, such as diffusion tensor imaging (DTI) and nerve perfusion are currently under examination with respect to the clinical potential. If all other diagnostic methods, including clinical examination, electrophysiology and nerve sonography do not arrive at an unambiguous diagnosis of a peripheral neuropathy, MRN should be used. The special value of MRN is demonstrated particularly in complex nerve lesions, such as traumatic plexopathies and in partial fascicular neuropathies and many other indications. (orig.) [de

  3. Improving patient care through molecular diagnostics

    NARCIS (Netherlands)

    Perez, Edith A.; Pusztai, Lajos; van de Vijver, Marc

    2004-01-01

    Traditional cancer diagnostic techniques include assessment of histologic appearance, identification of specific tumor subtypes, tumor grading, assessment of lymph node status, and presence of metastasis. These are useful for initial evaluation, but are limited in their ability to predict response

  4. Pulmonary carcinoma. Diagnostic and bronchoscopic treatment

    International Nuclear Information System (INIS)

    Caballero Duran, Hugo

    1997-01-01

    A historical recount of the bronchoscopy is made, from its beginnings 100 years ago, in a same way some techniques of diagnostic and treatment are mentioned, as the laser, fluorescence, cryotherapy, etc

  5. An edge over diagnostic setup

    Directory of Open Access Journals (Sweden)

    Sridhar Kannan

    2017-01-01

    Full Text Available Diagnostic setup proposed by H.D. Kingsley serves as a practical aid in treatment planning and diagnosis. These setups have some inherent shortcomings. A simple technique of duplication of the setups in dental stone can solve problems encountered before as well as provide many other advantages over the conventional procedure. The diagnostic setup is prepared by the conventional method [Figure 1]. An alginate impression is then taken of the setups and poured in dental stone to obtain the derived treatment model [Figure 2]. The same setup can now be further modified for alternate lines of treatment. Subsequently models could then be obtained as required [Figure 3].

  6. Diagnostic imaging in internal medicine

    International Nuclear Information System (INIS)

    Eisenberg, R.L.

    1985-01-01

    This book examines medical diagnostic techniques. Topics considered include biological considerations in the approach to clinical medicines; infectious diseases; disorders of the heart; disorders of the vascular system; disorders of the respiratory system; diseases of the kidneys and urinary tract; disorders of the alimentary tract; disorders of the hepatobiliary system and pancreas; disorders of the hematopoietic system; disorders of bone and bone mineralization; disorders of the joints, connective tissues, and striated muscles; disorders of the nervous system; miscellaneous disorders; and procedures in diagnostic imaging

  7. Diagnostic reasoning strategies and diagnostic success.

    Science.gov (United States)

    Coderre, S; Mandin, H; Harasym, P H; Fick, G H

    2003-08-01

    Cognitive psychology research supports the notion that experts use mental frameworks or "schemes", both to organize knowledge in memory and to solve clinical problems. The central purpose of this study was to determine the relationship between problem-solving strategies and the likelihood of diagnostic success. Think-aloud protocols were collected to determine the diagnostic reasoning used by experts and non-experts when attempting to diagnose clinical presentations in gastroenterology. Using logistic regression analysis, the study found that there is a relationship between diagnostic reasoning strategy and the likelihood of diagnostic success. Compared to hypothetico-deductive reasoning, the odds of diagnostic success were significantly greater when subjects used the diagnostic strategies of pattern recognition and scheme-inductive reasoning. Two other factors emerged as independent determinants of diagnostic success: expertise and clinical presentation. Not surprisingly, experts outperformed novices, while the content area of the clinical cases in each of the four clinical presentations demonstrated varying degrees of difficulty and thus diagnostic success. These findings have significant implications for medical educators. It supports the introduction of "schemes" as a means of enhancing memory organization and improving diagnostic success.

  8. Modern diagnostic capabilities for vasospastic angina diagnostics (intracoronary provocative testing

    Directory of Open Access Journals (Sweden)

    А. А. Обединский

    2017-04-01

    Full Text Available This review is devoted to a topical problem of modern cardiology – techniques of diagnosing vasospastic angina. The results of retrospective and prospective studies on the efficacy and safety of vasospastic angina diagnostics are reviewed. The literature on the prevalence, progression and treatment of this pathology is discussed.Received 13 January 2017. Accepted 6 February 2017.Financing: The study did not have sponsorship.Conflict of interest: The authors declare no conflict of interest.

  9. Diagnostic imaging of shoulder impingement

    International Nuclear Information System (INIS)

    Merl, T.; Weinhardt, H.; Oettl, G.; Lenz, M.; Riel, K.A.

    1996-01-01

    Magnetic resonance imaging is a method that has been advancing in the last few years to the modality of choice for diagnostic evaluation of the bone joints, as the method is capable of imaging not only the ossous but also the soft tissue components of the joint. MRI likewise has become an accepted method for diagnostic evaluation of syndromes of the shoulder, with high diagnostic accuracy in detecting rotator cuff lesions, or as an efficient MRI arthrography for evaluation of the instability or lesions of the labrocapsular complex. In the evaluation of early stages of shoulder impingement, the conventional MRI technique as a static technique yields indirect signs which in many cases do not provide the diagnostic certainty required in order to do justice to the functional nature of the syndrome. In these cases, functional MRI for imaging of the arm in abducted position and in rotational movement may offer a chance to early detect impingement and thus identify patients who will profit from treatment at an early stage [de

  10. Diagnostics for environmental aspects of pulsed atmospheric discharges

    International Nuclear Information System (INIS)

    Rutgers, W.R.; Veldhuizen, E.M. van

    2001-01-01

    Diagnostics for the study of pulsed atmospheric discharges are discussed. To obtain parameters for describing conversion processes of pollutants into harmless products many diagnostic techniques are in use and under development. In this contribution electrical, optical and chemical diagnostics used in air and wastewater remediation are reviewed

  11. Diagnostics for environmental aspects of pulsed atmospheric discharges

    Energy Technology Data Exchange (ETDEWEB)

    Rutgers, W.R.; Veldhuizen, E.M. van [Eindhoven Univ. of Technology (Netherlands). Dept. of Applied Physics

    2001-07-01

    Diagnostics for the study of pulsed atmospheric discharges are discussed. To obtain parameters for describing conversion processes of pollutants into harmless products many diagnostic techniques are in use and under development. In this contribution electrical, optical and chemical diagnostics used in air and wastewater remediation are reviewed.

  12. Spectroscopic and imaging diagnostics of pulsed laser deposition laser plasmas

    International Nuclear Information System (INIS)

    Thareja, Raj K.

    2002-01-01

    An overview of laser spectroscopic techniques used in the diagnostics of laser ablated plumes used for thin film deposition is given. An emerging laser spectroscopic imaging technique for the laser ablation material processing is discussed. (author)

  13. Nuclear diagnostics for inertial confinement fusion implosions

    International Nuclear Information System (INIS)

    Murphy, T.J.

    1997-01-01

    This abstract contains viewgraphs on nuclear diagnostic techniques for inertial confinement fusion implosions. The viewgraphs contain information on: reactions of interest in ICF; advantages and disadvantages of these methods; the properties nuclear techniques can measure; and some specifics on the detectors used

  14. Rifle Marksmanship Diagnostic and Training Guide

    Science.gov (United States)

    2011-05-01

    there any techniques you use to help prepare Soldiers to transition to firing with aiming lights (PEQ-2 or PAQ -4) and night vision goggles (ARM 1)? If...firing skills with the PAQ -4? A‐5    15. Are there any other diagnostic techniques you use that we haven’t discussed? a. Think back on your

  15. Radiologic diagnostics of dementia

    International Nuclear Information System (INIS)

    Essig, M.; Schoenberg, S.O.

    2003-01-01

    Dementia is one of the most common diseases in the elderly population and is getting more and more important with the ageing of the population. A radiologic structural examination with CT or MRI is meanwhile a standard procedure in the diagnostic work up of patients with dementia syndrome. Radiology enables an early diagnosis and a differential diagnosis between different causes of dementia. Because structural changes occur only late in the disease process, a more detailed structural analysis using volumetric techniques or the use of functional imaging techniques is mandatory. These days, structural imaging uses MRI which enables to detect early atrophic changes at the medial temporal lobe with focus on the amygdala hippocampal complex. These changes are also present in the normal ageing process. In patients with Alzheimer's disease, however, they are more rapid and more pronounced. The use of functional imaging methods such as perfusion MRI, diffusion MRI or fMRI allow new insights into the pathophysiologic changes of dementia. The article gives an overview of the current status of structural imaging and an outlook into the potential of functional imaging methods. Detailed results of structural and functional imaging are presented in other articles of this issue. (orig.) [de

  16. A Self-Diagnostic System for the M6 Accelerometer

    Science.gov (United States)

    Flanagan, Patrick M.; Lekki, John

    2001-01-01

    The design of a Self-Diagnostic (SD) accelerometer system for the Space Shuttle Main Engine is presented. This retrofit system connects diagnostic electronic hardware and software to the current M6 accelerometer system. This paper discusses the general operation of the M6 accelerometer SD system and procedures for developing and evaluating the SD system. Signal processing techniques using M6 accelerometer diagnostic data are explained. Test results include diagnostic data responding to changing ambient temperature, mounting torque and base mounting impedance.

  17. XII All-Russian conference Diagnostics of high-temperature plasma. Abstracts of reports and conference program

    International Nuclear Information System (INIS)

    2007-01-01

    Abstracts of reports made on the XII All-Russian conference on high-temperature plasma diagnostics are presented. The different methods of hot plasma diagnostics are considered, namely microwave diagnostic methods, laser diagnostic techniques, X-ray plasma diagnostics and corpuscular diagnostic methods. The particular attention is given to wall plasma diagnostics and diagnostics of inertial synthesis systems. Current diagnostic tools and metrological provision for plasma diagnostics are considered. The diagnostic complexes of thermonuclear devices are described. The problems of experimental data processing are discussed [ru

  18. Procedures in diagnostic radiology

    International Nuclear Information System (INIS)

    Doyle, T.; Hare, W.S.C.; Thomson, K.; Tess, B.

    1989-01-01

    This book outlines the various procedures necessary for the successful practice of diagnostic radiology. Topics covered are: general principles, imaging of the urinary and gastrointestinal tracts, vascular radiology, arthrography, and miscellaneous diagnostic radiologic procedures

  19. Diagnostic Algorithm Benchmarking

    Science.gov (United States)

    Poll, Scott

    2011-01-01

    A poster for the NASA Aviation Safety Program Annual Technical Meeting. It describes empirical benchmarking on diagnostic algorithms using data from the ADAPT Electrical Power System testbed and a diagnostic software framework.

  20. Calibration issues for neutron diagnostics

    International Nuclear Information System (INIS)

    Sadler, G.J.; Adams, J.M.; Barnes, C.W.

    1997-01-01

    The performance of diagnostic systems are limited by their weakest constituents, including their calibration issues. Neutron diagnostics are notorious for problems encountered while determining their absolute calibrations, due mainly to the nature of the neutron transport problem. In order to facilitate the determination of an accurate and precise calibration, the diagnostic design should be such as to minimize the scattered neutron flux. ITER will use a comprehensive set of neutron diagnostics--comprising radial and vertical neutron cameras, neutron spectrometers, a neutron activation system and internal and external fission chambers--to provide accurate measurements of fusion power and power densities as a function of time. The calibration of such an important diagnostic system merits careful consideration. Some thoughts have already been given to this subject during the conceptual design phase in relation to the time-integrated neutron activation and time-dependent neutron yield monitors. However, no overall calibration strategy has been worked out so far. This paper represents a first attempt to address this vital issue. Experience gained from present large tokamaks (JET, TFTR and JT60U) and proposals for ITER are reviewed. The need to use a 14-MeV neutron generator as opposed to radioactive sources for in-situ calibration of D-T diagnostics will be stressed. It is clear that the overall absolute determination of fusion power will have to rely on a combination of nuclear measuring techniques, for which the provision of accurate and independent calibrations will constitute an ongoing process as ITER moves from one phase of operation to the next

  1. Decision analysis to complete diagnostic research by closing the gap between test characteristics and cost-effectiveness

    NARCIS (Netherlands)

    Schaafsma, Joanna D.; van der Graaf, Yolanda; Rinkel, Gabriel J. E.; Buskens, Erik

    2009-01-01

    Objective: The lack of a standard methodology in diagnostic research impedes adequate evaluation before implementation of constantly developing diagnostic techniques. We discuss the methodology of diagnostic research and underscore the relevance of decision analysis in the process of evaluation of

  2. Cone-beam computed tomography versus digital periapical radiography in the detection of artificially created periapical lesions: A pilot study of the diagnostic accuracy of endodontists using both techniques

    Energy Technology Data Exchange (ETDEWEB)

    Campello, Abdrea Fagundes; Goncalves, Lucio Souza; Marques, Fabio vidal [Faculty of Dentistry, Estacio de Sa University, Rio de Janeiro (Brazil); Guedes, Fabio Ribeiro [Faculty of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro (Brazil)

    2017-03-15

    The aim of this study was to compare the diagnostic accuracy of previously trained endodontists in the detection of artificially created periapical lesions using cone-beam computed tomography (CBCT) and digital periapical radiography (DPR). An ex vivo model using dry skulls was used, in which simulated apical lesions were created and then progressively enlarged using no.1/2, no.2, no.4, and no.6 round burs. A total of 11 teeth were included in the study, and 110 images were obtained with CBCT and with an intraoral digital periapical radiographic sensor (Instrumentarium dental, Tuusula, Finland) initially and after each bur was used. Specificity and sensitivity were calculated. All images were evaluated by 10 previously trained, certified endodontists. Agreement was calculated using the kappa coefficient. The accuracy of each method in detecting apical lesions was calculated using the chi-square test. The kappa coefficient between examiners showed low agreement (range, 0.17-0.64). No statistical difference was found between CBCT and DPR in teeth without apical lesions (P=.15). The accuracy for CBCT was significantly higher than for DPR in all corresponding simulated lesions (P<.001). The correct diagnostic rate for CBCT ranged between 56.9% and 73.6%. The greatest difference between CBCT and DPR was seen in the maxillary teeth (CBCT, 71.4%; DPR, 28.6%; P<.01) and multi-rooted teeth (CBCT, 83.3%; DPR, 33.3%; P<.01). CBCT allowed higher accuracy than DPR in detecting simulated lesions for all simulated lesions tested. Endodontists need to be properly trained in interpreting CBCT scans to achieve higher diagnostic accuracy.

  3. A recommender system for medical imaging diagnostic.

    Science.gov (United States)

    Monteiro, Eriksson; Valente, Frederico; Costa, Carlos; Oliveira, José Luís

    2015-01-01

    The large volume of data captured daily in healthcare institutions is opening new and great perspectives about the best ways to use it towards improving clinical practice. In this paper we present a context-based recommender system to support medical imaging diagnostic. The system relies on data mining and context-based retrieval techniques to automatically lookup for relevant information that may help physicians in the diagnostic decision.

  4. Knowledge based diagnostics in nuclear power plants

    International Nuclear Information System (INIS)

    Baldeweg, F.; Fiedler, U.; Weiss, F.P.; Werner, M.

    1987-01-01

    In this paper a special process diagnostic system (PDS) is presented. It must be seen as the result of a long term work on computerized process surveillance and control; it includes a model based system for noise analysis of mechanical vibrations, which has recently been enhanced by using of knowledge based technique (expert systems). The paper discusses the process diagnostic frame concept and emphasize the vibration analysis expert system

  5. X-ray hot plasma diagnostics

    International Nuclear Information System (INIS)

    Cojocaru, E.

    1984-11-01

    X-ray plasma emission study is powerful diagnostic tool of hot plasmas. In this review article the main techniques of X-ray plasma emission measurement are shortly presented: X-ray spectrometry using absorbent filters, crystal and grating spectrometers, imaging techniques using pinhole cameras, X-ray microscopes and Fresnel zone plate cameras, X-ray plasma emission calorimetry. Advances in these techniques with examples for different hot plasma devices are also presentes. (author)

  6. Applying Diagnostics to Enhance Cable System Reliability (Cable Diagnostic Focused Initiative, Phase II)

    Energy Technology Data Exchange (ETDEWEB)

    Hartlein, Rick [Georgia Tech Research Corporation (GTRC), Atlanta, GA (United States). National Electric Energy Testing, Research and Applications Center (NEETRAC); Hampton, Nigel [Georgia Tech Research Corporation (GTRC), Atlanta, GA (United States). National Electric Energy Testing, Research and Applications Center (NEETRAC); Perkel, Josh [Georgia Tech Research Corporation (GTRC), Atlanta, GA (United States). National Electric Energy Testing, Research and Applications Center (NEETRAC); Hernandez, JC [Univ. de Los Andes, Merida (Venezuela); Elledge, Stacy [Georgia Tech Research Corporation (GTRC), Atlanta, GA (United States). National Electric Energy Testing, Research and Applications Center (NEETRAC); del Valle, Yamille [Georgia Tech Research Corporation (GTRC), Atlanta, GA (United States). National Electric Energy Testing, Research and Applications Center (NEETRAC); Grimaldo, Jose [Georgia Inst. of Technology, Atlanta, GA (United States). School of Electrical and Computer Engineering; Deku, Kodzo [Georgia Inst. of Technology, Atlanta, GA (United States). George W. Woodruff School of Mechanical Engineering

    2016-02-01

    The Cable Diagnostic Focused Initiative (CDFI) played a significant and powerful role in clarifying the concerns and understanding the benefits of performing diagnostic tests on underground power cable systems. This project focused on the medium and high voltage cable systems used in utility transmission and distribution (T&D) systems. While many of the analysis techniques and interpretations are applicable to diagnostics and cable systems outside of T&D, areas such as generating stations (nuclear, coal, wind, etc.) and other industrial environments were not the focus. Many large utilities in North America now deploy diagnostics or have changed their diagnostic testing approach as a result of this project. Previous to the CDFI, different diagnostic technology providers individually promoted their approach as the “the best” or “the only” means of detecting cable system defects.

  7. Nuclear diagnostics in support of ICF experiments

    International Nuclear Information System (INIS)

    Moran, M.J.; Hall, J.

    1996-01-01

    As the yields of Inertial Confinement Fusion (ICF) experiments increase to NIF levels new diagnostic techniques for studying details of fusion burn behavior will become feasible. The new techniques will provide improved measurements of fusion burn temperature and history. Improved temperature measurements might be achieved with magnetic spectroscopy of fusion neutrons. High-bandwidth fusion reaction history will be measured with fusion-specific γ-ray diagnostics. Additional energy-resolved γ-ray might be able to study a selection of specific behaviors during fusion burn. Present ICF yields greater than 10 13 neutrons are sufficient to demonstrate the basic methods that underlie the new techniques. As ICF yields increase, the diagnostics designs adjusted accordingly in order to provide clear and specific data on fusion burn performance

  8. Laboratory diagnostics of malaria

    Science.gov (United States)

    Siahaan, L.

    2018-03-01

    Even now, malaria treatment should only be administered after laboratory confirmation. There are several principal methods for diagnosing malaria. All these methods have their disadvantages.Presumptive treatment of malaria is widely practiced where laboratory tests are not readily available. Microscopy of Giemsa-stained thick and thin blood films remains the gold standard for the diagnosis of malaria infection. The technique of slide preparation, staining and reading are well known and standardized, and so is the estimate of the parasite density and parasite stages. Microscopy is not always available or feasible at primary health services in limited resource settings due to cost, lack of skilled manpower, accessories and reagents required. Rapid diagnostic tests (RDTs) are potential tools for parasite-based diagnosis since the tests are accurate in detecting malaria infections and are easy to use. The test is based on the capture of parasite antigen that released from parasitized red blood cells using monoclonal antibodies prepared against malaria antigen target. Polymerase Chain Reaction (PCR), depend on DNA amplification approaches and have higher sensitivity than microscopy. PCR it is not widely used due to the lack of a standardized methodology, high costs, and the need for highly-trained staff.

  9. Patient dosimetry in diagnostic radiology

    International Nuclear Information System (INIS)

    Shrimpton, P.C.

    2000-01-01

    Full text: X-ray examinations remain an essential and widely used diagnostic tool in medicine and hence the most significant source of exposure to man-made radiation for populations. Patterns of practice in diagnostic radiology continue to evolve, with overall growth in the numbers of procedures worldwide and, particularly in developed countries, increasing importance for complex procedures such as computed tomography (CT) and interventional techniques. In order to maximise the benefits from x-rays relative to the associated radiation risks, there is a need to ensure the prior justification of all examinations and the optimisation of patient protection such that doses are as low as reasonably practicable to meet specific clinical requirements. Accordingly, patient dosimetry is a fundamental requirement in diagnostic radiology. Detailed measurements for the assessment of risks or comparison of different types of procedure require the estimation of organ and effective doses. Such comprehensive dosimetry necessarily involves the simulation of clinical practice using anthropomorphic phantoms, with either measurements in a physical phantom or calculations utilising a mathematical phantom. Simpler measurements for the routine monitoring of dose in x-ray departments can be based on practical quantities such as entrance surface dose, dose-area product and, for CT, weighted CT dose index and dose-length product. Widescale surveys reveal significant variations between departments in the typical doses for a given type of procedure and potential scope for dose reductions. In order to promote improvements in practice, the results of periodic dose surveys in departments should be compared with appropriate standards, such as diagnostic reference levels for adult and paediatric patients, that are set nationally or locally for the purposes of promoting critical review of the equipment and techniques in use. Patient dosimetry should form an essential element of routine quality

  10. Time-resolved x-ray diagnostics

    International Nuclear Information System (INIS)

    Lyons, P.B.

    1981-01-01

    Techniques for time-resolved x-ray diagnostics will be reviewed with emphasis on systems utilizing x-ray diodes or scintillators. System design concerns for high-bandwidth (> 1 GHz) diagnostics will be emphasized. The limitations of a coaxial cable system and a technique for equalizing to improve bandwidth of such a system will be reviewed. Characteristics of new multi-GHz amplifiers will be presented. An example of a complete operational system on the Los Alamos Helios laser will be presented which has a bandwidth near 3 GHz over 38 m of coax. The system includes the cable, an amplifier, an oscilloscope, and a digital camera readout

  11. Instrumentation for localized superconducting cavity diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Conway, Z. A. [Argonne National Lab. (ANL), Argonne, IL (United States). Physics Division; Ge, M. [Cornell Lab. for Accelerator-Based Sciences and Education, Ithaca, NY (United States); Iwashita, Y. [Kyoto Univ. (Japan)

    2017-01-12

    Superconducting accelerator cavities are now routinely operated at levels approaching the theoretical limit of niobium. To achieve these operating levels more information than is available from the RF excitation signal is required to characterize and determine fixes for the sources of performance limitations. This information is obtained using diagnostic techniques which complement the analysis of the RF signal. In this paper we describe the operation and select results from three of these diagnostic techniques: the use of large scale thermometer arrays, second sound wave defect location and high precision cavity imaging with the Kyoto camera.

  12. Application of diagnostic system for diesel engine

    International Nuclear Information System (INIS)

    Yoshinaga, Takeshi; Hayashi, Haruji; Usui, Hiromi; Tsuruzono, Atsuya; Matsuda, Takafumi

    2008-01-01

    The Japan Atomic Power Company (JAPC) began to implement Condition Based Maintenance (CBM) for rotating components (pumps, fans and electric motors) from 1999 and, also has begun to apply diesel engine diagnostic techniques at our three nuclear power plants since 2004. This paper provides a description of the CBM methods used for diesel engines in nuclear standby service, a summary of the procedures to introduce these diagnostic techniques to our nuclear power plants, and experience with the application of these methods to JAPC nuclear power plants. (author)

  13. TFTR diagnostic vacuum controller

    International Nuclear Information System (INIS)

    Olsen, D.; Persons, R.

    1981-01-01

    The TFTR diagnostic vacuum controller (DVC) provides in conjunction with the Central Instrumentation Control and Data Acquisition System (CICADA), control and monitoring for the pumps, valves and gauges associated with each individual diagnostic vacuum system. There will be approximately 50 systems on TFTR. Two standard versions of the controller (A and B) wil be provided in order to meet the requirements of two diagnostic manifold arrangements. All pump and valve sequencing, as well as protection features, will be implemented by the controller

  14. Modified diagnosis of cardiovascular diseases: Application and comparison of diagnostic techniques in clinical medicine, radiology, ultrasonography and nuclear medicine. Final report. Einsatz und Vergleich klinischer, roentgenologischer, sonographischer und nuklearmedizinischer Methoden zur abgestuften Diagnostik von Herzkrankheiten. Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Adam, W.; Boettcher, D.; Christl, H.; Baew-Christow, T.; Holper, H.; Meindl, S.; Meyer, U.; Pfannenstiel, P.

    1985-01-01

    The main point of interest of the project is the question whether ultrasonography, myocardial scintiscanning, and radionuclide angiocardiography can replace the invasive techniques of cardiovascular diagnosis, and thus save costs at that. The results show that the above non-invasive techniques are indispensable in case of a diagnosis for cardiosurgery, almost sufficient in case of valvular heart disease, and sufficient in all cases of cardiomyopathy. Optimally planned application of the non-invasive methods could save about DM 7.3 millions a year in the FRG. (TRV).

  15. Vibration diagnostics instrumentation for ILC

    Energy Technology Data Exchange (ETDEWEB)

    Bertolini, A.

    2007-06-15

    The future e{sup -}e{sup +} 500 GeV International Linear Collider will rely on unprecedented nanometer scale particle beam size at the interaction point, in order to achieve the design luminosity. Tight tolerances on static and dynamic alignment of the accelerator cavities and optical components are demanded to transport and focus the high energy electron and positron beams with reasonable position jitter and low emittance. A brief review of techniques and devices evaluated and developed so far for the vibration diagnostics of the machine is presented in this paper. (orig.)

  16. Vibration diagnostics instrumentation for ILC

    International Nuclear Information System (INIS)

    Bertolini, A.

    2007-06-01

    The future e - e + 500 GeV International Linear Collider will rely on unprecedented nanometer scale particle beam size at the interaction point, in order to achieve the design luminosity. Tight tolerances on static and dynamic alignment of the accelerator cavities and optical components are demanded to transport and focus the high energy electron and positron beams with reasonable position jitter and low emittance. A brief review of techniques and devices evaluated and developed so far for the vibration diagnostics of the machine is presented in this paper. (orig.)

  17. Psychologists' diagnostic processes during a diagnostic interview

    NARCIS (Netherlands)

    Groenier, Marleen; Beerthuis, Vos R.J.; Pieters, Julius Marie; Witteman, C.L.M.; Witteman, Cilia L.M.; Swinkels, Jan A.

    2011-01-01

    In mental health care, psychologists assess clients’ complaints, analyze underlying problems, and identify causes for these problems, to make treatment decisions. We present a study on psychologists’ diagnostic processes, in which a mixed-method approach was employed. We aimed to identify a common

  18. Diagnostic nerve ultrasonography

    International Nuclear Information System (INIS)

    Baeumer, T.; Grimm, A.; Schelle, T.

    2017-01-01

    For the diagnostics of nerve lesions an imaging method is necessary to visualize peripheral nerves and their surrounding structures for an etiological classification. Clinical neurological and electrophysiological investigations provide functional information about nerve lesions. The information provided by a standard magnetic resonance imaging (MRI) examination is inadequate for peripheral nerve diagnostics; however, MRI neurography is suitable but on the other hand a resource and time-consuming method. Using ultrasonography for peripheral nerve diagnostics. With ultrasonography reliable diagnostics of entrapment neuropathies and traumatic nerve lesions are possible. The use of ultrasonography for neuropathies shows that a differentiation between different forms is possible. Nerve ultrasonography is an established diagnostic tool. In addition to the clinical examination and clinical electrophysiology, structural information can be obtained, which results in a clear improvement in the diagnostics. Ultrasonography has become an integral part of the diagnostic work-up of peripheral nerve lesions in neurophysiological departments. Nerve ultrasonography is recommended for the diagnostic work-up of peripheral nerve lesions in addition to clinical and electrophysiological investigations. It should be used in the clinical work-up of entrapment neuropathies, traumatic nerve lesions and spacy-occupying lesions of nerves. (orig.) [de

  19. Ongoing experiments: diagnostics requirements

    International Nuclear Information System (INIS)

    Dickerman, C.E.

    1976-01-01

    The paper reviews the fuel motion diagnostics needs for ongoing LMFBR safety experiments over approximately the next five years, with the discussion centered on TREAT. Brief comments on the direction in which clad motion diagnostics requirements are expected to develop are also presented

  20. Clinical diagnostic ultrasound

    International Nuclear Information System (INIS)

    Barnett, E.; Morley, P.

    1986-01-01

    This textbook on diagnostic ultrasound covers the main systems, with emphasis being placed on the clinical application of diagnostic ultrasound in everyday practice. It provides not only a textbook for postgraduates (particularly FRCR candidates), but also a reference work for practitioners of clinical ultrasound and clinicians generally

  1. Gearbox vibration diagnostic analyzer

    Science.gov (United States)

    1992-01-01

    This report describes the Gearbox Vibration Diagnostic Analyzer installed in the NASA Lewis Research Center's 500 HP Helicopter Transmission Test Stand to monitor gearbox testing. The vibration of the gearbox is analyzed using diagnostic algorithms to calculate a parameter indicating damaged components.

  2. Diagnostics for PLX-alpha

    Science.gov (United States)

    Gilmore, Mark; Hsu, Scott

    2015-11-01

    The goal of the Plasma Liner eXperiment PLX-alpha at Los Alamos National Laboratory is to establish the viability of creating a spherically imploding plasma liner for MIF and HED applications, using a spherical array of supersonic plasma jets launched by innovative contoured-gap coaxial plasma guns. PLX- α experiments will focus in particular on establishing the ram pressure and uniformity scalings of partial and fully spherical plasma liners. In order to characterize these parameters experimentally, a suite of diagnostics is planned, including multi-camera fast imaging, a 16-channel visible interferometer (upgraded from 8 channels) with reconfigurable, fiber-coupled front end, and visible and VUV high-resolution and survey spectroscopy. Tomographic reconstruction and data fusion techniques will be used in conjunction with interferometry, imaging, and synthetic diagnostics from modeling to characterize liner uniformity in 3D. Diagnostic and data analysis design, implementation, and status will be presented. Supported by the Advanced Research Projects Agency - Energy - U.S. Department of Energy.

  3. Image enhancement of digital periapical radiographs according to diagnostic tasks

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Jin Woo; Han, Won Jeong; Kim, Eun Kyung [Dept. of Oral and Maxillofacial Radiology, Dankook University College of Dentistry, Cheonan (Korea, Republic of)

    2014-03-15

    his study was performed to investigate the effect of image enhancement of periapical radiographs according to the diagnostic task. Eighty digital intraoral radiographs were obtained from patients and classified into four groups according to the diagnostic tasks of dental caries, periodontal diseases, periapical lesions, and endodontic files. All images were enhanced differently by using five processing techniques. Three radiologists blindly compared the subjective image quality of the original images and the processed images using a 5-point scale. There were significant differences between the image quality of the processed images and that of the original images (P<0.01) in all the diagnostic task groups. Processing techniques showed significantly different efficacy according to the diagnostic task (P<0.01). Image enhancement affects the image quality differently depending on the diagnostic task. And the use of optimal parameters is important for each diagnostic task.

  4. Image enhancement of digital periapical radiographs according to diagnostic tasks

    International Nuclear Information System (INIS)

    Choi, Jin Woo; Han, Won Jeong; Kim, Eun Kyung

    2014-01-01

    his study was performed to investigate the effect of image enhancement of periapical radiographs according to the diagnostic task. Eighty digital intraoral radiographs were obtained from patients and classified into four groups according to the diagnostic tasks of dental caries, periodontal diseases, periapical lesions, and endodontic files. All images were enhanced differently by using five processing techniques. Three radiologists blindly compared the subjective image quality of the original images and the processed images using a 5-point scale. There were significant differences between the image quality of the processed images and that of the original images (P<0.01) in all the diagnostic task groups. Processing techniques showed significantly different efficacy according to the diagnostic task (P<0.01). Image enhancement affects the image quality differently depending on the diagnostic task. And the use of optimal parameters is important for each diagnostic task.

  5. Bone marrow lesions: A systematic diagnostic approach

    International Nuclear Information System (INIS)

    Grande, Filippo Del; Farahani, Sahar J; Carrino, John A; Chhabra, Avneesh

    2014-01-01

    Bone marrow lesions on magnetic resonance (MR) imaging are common and may be seen with various pathologies. The authors outline a systematic diagnostic approach with proposed categorization of various etiologies of bone marrow lesions. Utilization of typical imaging features on conventional MR imaging techniques and other problem-solving techniques, such as chemical shift imaging and diffusion-weighted imaging (DWI), to achieve accurate final diagnosis has been highlighted

  6. Bone marrow lesions: A systematic diagnostic approach

    Directory of Open Access Journals (Sweden)

    Filippo Del Grande

    2014-01-01

    Full Text Available Bone marrow lesions on magnetic resonance (MR imaging are common and may be seen with various pathologies. The authors outline a systematic diagnostic approach with proposed categorization of various etiologies of bone marrow lesions. Utilization of typical imaging features on conventional MR imaging techniques and other problem-solving techniques, such as chemical shift imaging and diffusion-weighted imaging (DWI, to achieve accurate final diagnosis has been highlighted.

  7. PVT Degradation Studies: Acoustic Diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Dib, Gerges [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Tucker, Brian J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kouzes, Richard T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Smith, Philip J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2017-04-01

    Under certain environmental conditions, polyvinyl toluene (PVT) plastic scintillator has been observed to undergo internal fogging. This document reports on a study of acoustic techniques to determine whether they can provide a diagnostic for the fogging of PVT. Different ultrasound techniques were employed for detecting the level of internal fogging in PVT, including wave velocity measurements, attenuation, nonlinear acoustics, and acoustic microscopy. The results indicate that there are linear relations between the wave velocity and wave attenuation with the level of internal fogging. The effects of fogging on ultrasound wave attenuation is further verified by acoustic microscopy imaging, where regions with fog in the specimen demonstration higher levels of attenuation compared to clear regions. Results from the nonlinear ultrasound measurements were inconclusive due to high sensitivities to transducer coupling and fixture variabilities.

  8. Diagnostic imaging in focal epilepsy

    International Nuclear Information System (INIS)

    Zlatareva, D.

    2013-01-01

    Focal epilepsies account for 60% of all seizure disorders worldwide. In this review the classic and new classification system of epileptic seizures and syndromes as well as genetic forms are discussed. Magnetic resonance (MR) is the technique of choice for diagnostic imaging in focal epilepsy because of its sensitivity and high tissue contrast. The review is focused on the lack of consensus of imaging protocols and reported findings in refractory epilepsy. The most frequently encountered MRI findings in epilepsy are reported and their imaging characteristics are depicted. Diagnosis of hippocampal sclerosis and malformations of cortical development as two major causes of refractory focal epilepsy is described in details. Some promising new techniques as positron emission tomography computed tomography (PET/CT) and MR and PET/CT fusion are briefly discussed. Also the relevance of adequate imaging in focal epilepsy, some practical points in imaging interpretation and differential diagnosis are highlighted. (author)

  9. Feline immunodeficiency virusinfection: a comparative study of different diagnostic techniques Infecção pelo vírus da imunodeficiência felina: estudo comparativo de diferentes técnicas de diagnóstico

    Directory of Open Access Journals (Sweden)

    E. Mortola

    2004-02-01

    Full Text Available This study evaluated an indirect immunofluorescence assay (IFA to detect feline immunodeficiency virus infection (FIV antibody in a comprehensive epidemiological survey of FIV in Argentina. IFA modified in our laboratory, was compared with two other immunoassays, western blot (WB and a sandwich immunochromatographic commercial kit (SI, and also with a direct polymerase chain reaction (PCR method that detects proviral DNA. IFA showed to be a test with high sensitivity and specificity, and could be useful as a diagnostic tool in epidemiological studies. The presence of a low percentage of results with non-specific reactivity in the IFA could be resolved with further testing or use of an alternative method.Avaliou-se a técnica de imunofluorescência indireta (IFA na detecção de anticorpos contra o vírus da imunodeficiência felina (FIV numa pesquisa epidemiológica do FIV na Argentina. A IFA foi modificada e comparada com duas outras técnicas imunológicas: western blot (WB e imunocromatografia em camadas (SI com kit comercial e também com reação em cadeia de polimerase (PCR para detecção do DNA proviral. A IFA mostrou ser um teste com alta sensibilidade e especificidade e poderá ser empregada como ferramenta útil em estudos epidemiológicos. A baixa porcentagem de reatividade não específica pode ser esclarecida com testes mais avançados ou usando métodos alternativos.

  10. Infrared laser diagnostics for ITER

    International Nuclear Information System (INIS)

    Hutchinson, D.P.; Richards, R.K.; Ma, C.H.

    1995-01-01

    Two infrared laser-based diagnostics are under development at ORNL for measurements on burning plasmas such as ITER. The primary effort is the development of a CO 2 laser Thomson scattering diagnostic for the measurement of the velocity distribution of confined fusion-product alpha particles. Key components of the system include a high-power, single-mode CO 2 pulsed laser, an efficient optics system for beam transport and a multichannel low-noise infrared heterodyne receiver. A successful proof-of-principle experiment has been performed on the Advanced Toroidal Facility (ATF) stellerator at ORNL utilizing scattering from electron plasma frequency satellites. The diagnostic system is currently being installed on Alcator C-Mod at MIT for measurements of the fast ion tail produced by ICRH heating. A second diagnostic under development at ORNL is an infrared polarimeter for Faraday rotation measurements in future fusion experiments. A preliminary feasibility study of a CO 2 laser tangential viewing polarimeter for measuring electron density profiles in ITER has been completed. For ITER plasma parameters and a polarimeter wavelength of 10.6 microm, a Faraday rotation of up to 26 degree is predicted. An electro-optic polarization modulation technique has been developed at ORNL. Laboratory tests of this polarimeter demonstrated a sensitivity of ≤ 0.01 degree. Because of the similarity in the expected Faraday rotation in ITER and Alcator C-Mod, a collaboration between ORNL and the MIT Plasma Fusion Center has been undertaken to test this polarimeter system on Alcator C-Mod. A 10.6 microm polarimeter for this measurement has been constructed and integrated into the existing C-Mod multichannel two-color interferometer. With present experimental parameters for C-Mod, the predicted Faraday rotation was on the order of 0.1 degree. Significant output signals were observed during preliminary tests. Further experiment and detailed analyses are under way

  11. Myocardium scintiscanning with thallium-201 in case of idiopathic juvenile arteriosclerosis (description of a case and information on further applications of nuclear-medical diagnostic techniques in pediatric cardiology)

    International Nuclear Information System (INIS)

    Hoer, G.; Maul, F.D.; Munz, D.L.; Vettermann, H.

    1985-01-01

    In the field of pediatrics and the related literature, the analysis of myocardial perfusion and ventricular function using myocardium scintiscanning and radionuclide ventriculography is a subject discussed rather rarely, in contrast to the medical examination of adult patients where this is a well-established method. The authors have so far not found any information on the use of scintiscanning methods for the diagnosis of idiopathic juvenile arteriosclerosis and hence take the opportunity to describe a case of recent application of this method. In addition, findings and results are discussed that speak in favour of the use of further nuclear-medical techniques in pediatric cardiology. (orig./MG) [de

  12. The future of medical diagnostics: Review paper

    NARCIS (Netherlands)

    W.K. Jerjes (Waseem K.); T. Upile (Tahwinder); B.J. Wong (Brian J.); C.S. Betz (Christian S.); H.J.C.M. Sterenborg (Dick); M.J.H. Witjes (Max); K. Svanberg (Katarina); R. van Veen (Robert); M.A. Biel (Merrill A.); A.K. El-Naggar (Adel K.); C.A. Mosse (Charles A.); M. Olivo (Malini); R. Richards-Kortum (Rebecca); D.J. Robinson (Dominic); P.J. Rosen (Peter J.); A.G. Yodh (Arjun G.); C. Kendall (Catherine); J.F. Ilgner (Justus F.); A. Amelink (Arjen); V. Bagnato (Vanderlei); H. Barr (Hugh); L. Bolotine (Lina); I. Bigio (Irving); Z. Chen (Zhiyi); L.P. Choo-Smith; A.K. D'Cruz (Anil K.); A. Gillenwater (Ann); A. Leunig (Andreas); A.J. MacRobert (Alexander J.); G. McKenzie (Gordon); A. Sandison (Ann); K.C. Soo (Khee Chee); H. Stepp (Herbert); J.R.N. Stone; I.B. Tan (I. Bing); B.C. Wilson (Brian C.); H. Wolfsen (Herbert); C. Hopper (Colin)

    2011-01-01

    textabstractWhile histopathology of excised tissue remains the gold standard for diagnosis, several new, non-invasive diagnostic techniques are being developed. They rely on physical and biochemical changes that precede and mirror malignant change within tissue. The basic principle involves simple

  13. Laser diagnostics for picosecond e-beams

    International Nuclear Information System (INIS)

    Pogorelsky, I.; Ben-Zvi, I.

    1992-01-01

    We propose a novel approach to picosecond e-bunch/laser pulse synchronization and spatial alignment based upon refraction and reflection of a laser beam on a plasma column created by relativistic electrons traveling through a gas or solid optical material. The technique may be used in laser accelerators and for general subpicosecond e-beam diagnostics

  14. The LIDAR Thomson Scattering Diagnostic on JET

    DEFF Research Database (Denmark)

    Salzmann, H.; Bundgaard, J.; Gadd, A.

    1988-01-01

    By combining the time‐of‐flight or LIDAR principle with a Thomson backscatter diagnostic, spatial profiles of the electron temperature and density are measured in a magnetically confined fusion plasma. This technique was realized for the first time on the JET tokamak. A ruby laser (3‐J pulse ener...

  15. Diagnostic radiology - the impact of new technology

    International Nuclear Information System (INIS)

    Harrison, R.M.

    1989-01-01

    Recent technological advances that have led to the introduction of new or improved methods of diagnostic imaging are examined. In particular, the application of computer techniques for image acquisition and processing has facilitated new methods of image synthesis and analysis. (author)

  16. The future of medical diagnostics : review paper

    NARCIS (Netherlands)

    Jerjes, Waseem K.; Upile, Tahwinder; Wong, Brian J.; Betz, Christian S.; Sterenborg, Henricus J.; Witjes, Max J.; Berg, Kristian; van Veen, Robert; Biel, Merrill A.; El-Naggar, Adel K.; Mosse, Charles A.; Olivo, Malini; Richards-Kortum, Rebecca; Robinson, Dominic J.; Rosen, Jennifer; Yodh, Arjun G.; Kendall, Catherine; Ilgner, Justus F.; Amelink, Arjen; Bagnato, Vanderlei; Barr, Hugh; Bolotine, Lina; Bigio, Irving; Chen, Zhongping; Choo-Smith, Lin-Ping; D'Cruz, Anil K.; Gillenwater, Ann; Leunig, Andreas; MacRobert, Alexander J.; McKenzie, Gordon; Sandison, Ann; Soo, Khee C.; Stepp, Herbert; Stone, Nicholas; Svanberg, Katarina; Tan, I. Bing; Wilson, Brian C.; Wolfsen, Herbert; Hopper, Colin

    2011-01-01

    While histopathology of excised tissue remains the gold standard for diagnosis, several new, non-invasive diagnostic techniques are being developed. They rely on physical and biochemical changes that precede and mirror malignant change within tissue. The basic principle involves simple optical

  17. The future of medical diagnostics: review paper

    NARCIS (Netherlands)

    Jerjes, Waseem K.; Upile, Tahwinder; Wong, Brian J.; Betz, Christian S.; Sterenborg, Henricus J.; Witjes, Max J.; Berg, Kristian; van Veen, Robert; Biel, Merrill A.; El-Naggar, Adel K.; Mosse, Charles A.; Olivo, Malini; Richards-Kortum, Rebecca; Robinson, Dominic J.; Rosen, Jennifer; Yodh, Arjun G.; Kendall, Catherine; Ilgner, Justus F.; Amelink, Arjen; Bagnato, Vanderlei; Barr, Hugh; Bolotine, Lina; Bigio, Irving; Chen, Zhongping; Choo-Smith, Lin-Ping; D'Cruz, Anil K.; Gillenwater, Ann; Leunig, Andreas; MacRobert, Alexander J.; McKenzie, Gordon; Sandison, Ann; Soo, Khee C.; Stepp, Herbert; Stone, Nicholas; Svanberg, Katarina; Tan, I. Bing; Wilson, Brian C.; Wolfsen, Herbert; Hopper, Colin

    2011-01-01

    While histopathology of excised tissue remains the gold standard for diagnosis, several new, non-invasive diagnostic techniques are being developed. They rely on physical and biochemical changes that precede and mirror malignant change within tissue. The basic principle involves simple optical

  18. Evaluation of laboratory diagnostic methods for cryptosporidiosis ...

    African Journals Online (AJOL)

    The conventional method of modified Ziehl-Neelsen (MZN) is very laborious, and stool ... Objective: This research was set to evaluate the diagnostic efficacy of ... 93.1% (MZN to ELISA) with ELISA techniques showing the highest sensitivity at ...

  19. Experimental techniques; Techniques experimentales

    Energy Technology Data Exchange (ETDEWEB)

    Roussel-Chomaz, P. [GANIL CNRS/IN2P3, CEA/DSM, 14 - Caen (France)

    2007-07-01

    This lecture presents the experimental techniques, developed in the last 10 or 15 years, in order to perform a new class of experiments with exotic nuclei, where the reactions induced by these nuclei allow to get information on their structure. A brief review of the secondary beams production methods will be given, with some examples of facilities in operation or under project. The important developments performed recently on cryogenic targets will be presented. The different detection systems will be reviewed, both the beam detectors before the targets, and the many kind of detectors necessary to detect all outgoing particles after the reaction: magnetic spectrometer for the heavy fragment, detection systems for the target recoil nucleus, {gamma} detectors. Finally, several typical examples of experiments will be detailed, in order to illustrate the use of each detector either alone, or in coincidence with others. (author)

  20. Multispectral optical tweezers for molecular diagnostics of single biological cells

    Science.gov (United States)

    Butler, Corey; Fardad, Shima; Sincore, Alex; Vangheluwe, Marie; Baudelet, Matthieu; Richardson, Martin

    2012-03-01

    Optical trapping of single biological cells has become an established technique for controlling and studying fundamental behavior of single cells with their environment without having "many-body" interference. The development of such an instrument for optical diagnostics (including Raman and fluorescence for molecular diagnostics) via laser spectroscopy with either the "trapping" beam or secondary beams is still in progress. This paper shows the development of modular multi-spectral imaging optical tweezers combining Raman and Fluorescence diagnostics of biological cells.

  1. Diagnostics on Z (invited)

    International Nuclear Information System (INIS)

    Nash, T. J.; Derzon, M. S.; Chandler, G. A.; Fehl, D. L.; Leeper, R. J.; Porter, J. L.; Spielman, R. B.; Ruiz, C.; Cooper, G.; McGurn, J.

    2001-01-01

    The 100 ns, 20 MA pinch-driver Z is surrounded by an extensive set of diagnostics. There are nine radial lines of sight set at 12 o above horizontal and each of these may be equipped with up to five diagnostic ports. Instruments routinely fielded viewing the pinch from the side with these ports include x-ray diode arrays, photoconducting detector arrays, bolometers, transmission grating spectrometers, time-resolved x-ray pinhole cameras, x-ray crystal spectrometers, calorimeters, silicon photodiodes, and neutron detectors. A diagnostic package fielded on axis for viewing internal pinch radiation consists of nine lines of sight. This package accommodates virtually the same diagnostics as the radial ports. Other diagnostics not fielded on the axial or radial ports include current B-dot monitors, filtered x-ray scintillators coupled by fiber optics to streak cameras, streaked visible spectroscopy, velocity interferometric system for any reflector, bremsstrahlung cameras, and active shock breakout measurement of hohlraum temperature. The data acquisition system is capable of recording up to 500 channels and the data from each shot is available on the Internet. A major new diagnostic presently under construction is the BEAMLET backlighter. We will briefly describe each of these diagnostics and present some of the highest-quality data from them

  2. Ultrasound diagnostics of thyroid diseases

    International Nuclear Information System (INIS)

    Kharchenko, Vladimir P.; Kotlyarov, Peter M.; Mogutov, Mikhail S.; Sencha, Alexander N.; Patrunov, Yury N.; Belyaev, Denis V.; Alexandrov, Yury K.

    2010-01-01

    This book is based on the authors' extensive practical experience in the use of modern ultrasound, and other radiological methods, in the diagnosis of thyroid diseases. The authors have analyzed more than 100,000 ultrasound examinations performed between 1995 and 2008 in patients with thyroid and parathyroid disease, as well as many thousands of diagnostic and therapeutic ultrasound-guided minimally invasive procedures. The opening chapters include discussion of current ultrasound techniques, pitfalls, and the specifics of ultrasound examination of the thyroid in children. Detailed attention is then devoted to findings in the normal thyroid and in the presence of diffuse and focal changes. Further chapters focus on such topics as ultrasound examination after thyroid surgery and ultrasound diagnosis of parathyroid disease, recurrent goiter, and neck masses. Ultrasound-guided minimally invasive techniques, such as fine-needle aspiration biopsy, percutaneous laser ablation, and ethanol and glucocorticoid injections, are considered in depth. This up-to-date and richly illustrated book will interest and assist specialists in ultrasound diagnostics, radiologists, endocrinologists, and neck surgeons. (orig.)

  3. Cable Diagnostic Focused Initiative

    Energy Technology Data Exchange (ETDEWEB)

    Hartlein, R.A.; Hampton, R.N.

    2010-12-30

    This report summarizes an extensive effort made to understand how to effectively use the various diagnostic technologies to establish the condition of medium voltage underground cable circuits. These circuits make up an extensive portion of the electric delivery infrastructure in the United States. Much of this infrastructure is old and experiencing unacceptable failure rates. By deploying efficient diagnostic testing programs, electric utilities can replace or repair circuits that are about to fail, providing an optimal approach to improving electric system reliability. This is an intrinsically complex topic. Underground cable systems are not homogeneous. Cable circuits often contain multiple branches with different cable designs and a range of insulation materials. In addition, each insulation material ages differently as a function of time, temperature and operating environment. To complicate matters further, there are a wide variety of diagnostic technologies available for assessing the condition of cable circuits with a diversity of claims about the effectiveness of each approach. As a result, the benefits of deploying cable diagnostic testing programs have been difficult to establish, leading many utilities to avoid the their use altogether. This project was designed to help address these issues. The information provided is the result of a collaborative effort between Georgia Tech NEETRAC staff, Georgia Tech academic faculty, electric utility industry participants, as well as cable system diagnostic testing service providers and test equipment providers. Report topics include: •How cable systems age and fail, •The various technologies available for detecting potential failure sites, •The advantages and disadvantages of different diagnostic technologies, •Different approaches for utilities to employ cable system diagnostics. The primary deliverables of this project are this report, a Cable Diagnostic Handbook (a subset of this report) and an online

  4. A Comparison between Electrochemical Impedance Spectroscopy and Incremental Capacity-Differential Voltage as Li-ion Diagnostic Techniques to Identify and Quantify the Effects of Degradation Modes within Battery Management Systems

    Science.gov (United States)

    Pastor-Fernández, Carlos; Uddin, Kotub; Chouchelamane, Gael H.; Widanage, W. Dhammika; Marco, James

    2017-08-01

    Degradation of Lithium-ion batteries is a complex process that is caused by a variety of mechanisms. For simplicity, ageing mechanisms are often grouped into three degradation modes (DMs): conductivity loss (CL), loss of active material (LAM) and loss of lithium inventory (LLI). State of Health (SoH) is typically the parameter used by the Battery Management System (BMS) to quantify battery degradation based on the decrease in capacity and the increase in resistance. However, the definition of SoH within a BMS does not currently include an indication of the underlying DMs causing the degradation. Previous studies have analysed the effects of the DMs using incremental capacity and differential voltage (IC-DV) and electrochemical impedance spectroscopy (EIS). The aim of this study is to compare IC-DV and EIS on the same data set to evaluate if both techniques provide similar insights into the causes of battery degradation. For an experimental case of parallelized cells aged differently, the effects due to LAM and LLI were found to be the most pertinent, outlining that both techniques are correlated. This approach can be further implemented within a BMS to quantify the causes of battery ageing which would support battery lifetime control strategies and future battery designs.

  5. Research and development of an aimed magnetic lead current density-magnetic field diagnostic. Final report

    International Nuclear Information System (INIS)

    1985-01-01

    A diagnostics survey was made to provide a clear definition of advanced diagnostic needs and the limitations of current approaches in addressing those needs. Special attention was given to the adequacy with which current diagnostics are interfaced to signal processing/data acquisition devices and systems. Critical evaluations of selected alternative diagnostic techniques for future R and D activities are presented. The conceptual basis of the Aimed Magnetic Lead Gradiometric system as a current density/magnetic field diagnostic is established

  6. Plasma diagnostic reflectometry

    International Nuclear Information System (INIS)

    Cohen, B.I.; Afeyan, B.B.; Garrison, J.C.; Kaiser, T.B.; Luhmann, N.C. Jr.; Domier, C.W.; Chou, A.E.; Baang, S.

    1996-01-01

    Theoretical and experimental studies of plasma diagnostic reflectometry have been undertaken as a collaborative research project between the Lawrence Livermore National Laboratory (LLNL) and the University of California Department of Applied Science Plasma Diagnostics Group under the auspices of the Laboratory Directed Research and Development Program at LLNL. Theoretical analyses have explored the basic principles of reflectometry to understand its limitations, to address specific gaps in the understanding of reflectometry measurements in laboratory experiments, and to explore extensions of reflectometry such as ultra-short-pulse reflectometry. The theory has supported basic laboratory reflectometry experiments where reflectometry measurements can be corroborated by independent diagnostic measurements

  7. Multi-method automated diagnostics of rotating machines

    Science.gov (United States)

    Kostyukov, A. V.; Boychenko, S. N.; Shchelkanov, A. V.; Burda, E. A.

    2017-08-01

    The automated machinery diagnostics and monitoring systems utilized within the petrochemical plants are an integral part of the measures taken to ensure safety and, as a consequence, the efficiency of these industrial facilities. Such systems are often limited in their functionality due to the specifics of the diagnostic techniques adopted. As the diagnostic techniques applied in each system are limited, and machinery defects can have different physical nature, it becomes necessary to combine several diagnostics and monitoring systems to control various machinery components. Such an approach is inconvenient, since it requires additional measures to bring the diagnostic results in a single view of the technical condition of production assets. In this case, we mean by a production facility a bonded complex of a process unit, a drive, a power source and lines. A failure of any of these components will cause an outage of the production asset, which is unacceptable. The purpose of the study is to test a combined use of vibration diagnostics and partial discharge techniques within the diagnostic systems of enterprises for automated control of the technical condition of rotating machinery during maintenance and at production facilities. The described solutions allow you to control the condition of mechanical and electrical components of rotating machines. It is shown that the functionality of the diagnostics systems can be expanded with minimal changes in technological chains of repair and operation of rotating machinery. Automation of such systems reduces the influence of the human factor on the quality of repair and diagnostics of the machinery.

  8. Técnicas de diagnóstico en transformadores a partir de su respuesta en el dominio de la frecuencia. Estado mundial del arte. Parte II; Techniques of Diagnostic in Transformers from their Answer in Frequency Domain. World State of the Art. Part II

    Directory of Open Access Journals (Sweden)

    Orestes Hernández Areu

    2011-02-01

    Full Text Available Entre los métodos para el diagnóstico de transformadores de potencia se encuentran los métodos de detecciónde averías a través del llamado análisis de la respuesta en la frecuencia (FRA. En un artículo anterior, sepresentó la primera parte del estudio que se ha realizado del estado mundial del arte sobre las técnicas dediagnóstico de transformadores a partir de su respuesta en el dominio de la frecuencia y empleando latransformada rápida de Fourier (FFT. Esta segunda parte, trata específicamente, sobre los métodos dediagnóstico de transformadores mediante el análisis de la respuesta a un barrido de frecuencia (SFRA, sin lautilización de  la transformada rápida de Fourier (FFT.  In the methods for the diagnosis of power transformers there are the failure detection methods called frequencyresponse analysis (FRA. In a previous article, the first part of a study that has been carried out about theworld art state on the techniques of diagnostic in transformers from its response in the frequency domain andusing the fast Fourier transformed (FFT, was presented.This second part, tries specifically about the methodsof diagnostic of transformers by means of the sweeping frequency response analysis (SFRA, without usingthe fast Fourier tansformed (FFT.

  9. Active and Passive Diagnostic Signatures of Special Nuclear Materials

    Energy Technology Data Exchange (ETDEWEB)

    Myers, William L. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Karpius, Peter Joseph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Myers, Steven Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-26

    An overview will be given discussing signatures associated with special nuclear materials acquired using both active and passive diagnostic techniques. Examples of how technology advancements have helped improve diagnostic capabilities to meet the challenges of today’s applications will be discussed.

  10. Imaging diagnostics of the foot; Bildgebende Diagnostik des Fusses

    Energy Technology Data Exchange (ETDEWEB)

    Szeimies, Ulrike; Staebler, Axel [Radiologie in Muenchen-Harlaching, Muenchen (Germany); Walther, Markus (eds.) [Schoen-Klinik Muenchen-Harlaching, Muenchen (Germany). Zentrum fuer Fuss- und Sprunggelenkchirurgie

    2012-11-01

    The book on imaging diagnostics of the foot contains the following chapters: (1) Imaging techniques. (2) Clinical diagnostics. (3) Ankle joint and hind foot. (4) Metatarsus. (5) Forefoot. (6) Pathology of plantar soft tissue. (7) Nervous system diseases. (8) Diseases without specific anatomic localization. (9) System diseases including the foot. (10) Tumor like lesions. (11) Normative variants.

  11. Equipment for radiation diagnostics

    International Nuclear Information System (INIS)

    Tschunt, E.; Platz, W.

    1976-01-01

    The invention relates to an improvement of the line type of the plotter in an X-ray diagnostics apparatus enabling the production of distinguishable recordings by means of a single plot type. The construction is described explicitly. (UWI) [de

  12. National Convective Weather Diagnostic

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Current convective hazards identified by the National Convective Weather Detection algorithm. The National Convective Weather Diagnostic (NCWD) is an automatically...

  13. Diagnostic radiology: I

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    This chapter describes the historic development of diagnostic equipment for radiology. The problems associated with fluoroscope design are detailed and the current uses of updated technology, particularly digitization, are considered. Numerous historical photographs are included. 13 refs

  14. Prenatal Genetic Diagnostic Tests

    Science.gov (United States)

    ... are available for many inherited disorders. The main disadvantage is that diagnostic testing carries a very small ... chromosomes, arranged in order of size. Microarray: A technology that examines all of a person’s genes to ...

  15. Optics/Optical Diagnostics Laboratory

    Data.gov (United States)

    Federal Laboratory Consortium — The Optics/Optical Diagnostics Laboratory supports graduate instruction in optics, optical and laser diagnostics and electro-optics. The optics laboratory provides...

  16. Nanotechnology based diagnostics for neurological disorders

    Energy Technology Data Exchange (ETDEWEB)

    Kurek, Nicholas S; Chandra, Sathees B., E-mail: schandra@roosevelt.edu [Department of Biological, Chemical and Physical Sciences, Roosevelt University, Chicago, IL (United States)

    2012-07-01

    Nanotechnology involves probing and manipulating matter at the molecular level. Nanotechnology based molecular diagnostics have the potential to alleviate the suffering caused by many diseases, including neurological disorders, due to the unique properties of nanomaterials. Most neurological illnesses are multifactorial conditions and many of these are also classified as neurobehavioral disorders. Alzheimer's disease, Parkinson's disease, Huntington disease, cerebral ischemia, epilepsy, schizophrenia and autism spectrum disorders like Rett syndrome are some examples of neurological disorders that could be better treated, diagnosed, prevented and possibly cured using nanotechnology. In order to improve the quality of life for disease afflicted people, a wide range of nanomaterials that include gold and silica nanoparticles, quantum dots and DNA along with countless other forms of nanotechnology have been investigated regarding their usefulness in advancing molecular diagnostics. Other small scaled materials like viruses and proteins also have potential for use as molecular diagnostic tools. Information obtained from nanotechnology based diagnostics can be stored and manipulated using bioinformatics software. More advanced nanotechnology based diagnostic procedures for the acquisition of even greater proteomic and genomic knowledge can then be developed along with better ways to fight various diseases. Nanotechnology also has numerous applications besides those related to biotechnology and medicine. In this article, we will discuss and analyze many novel nanotechnology based diagnostic techniques at our disposal today. (author)

  17. Nanotechnology based diagnostics for neurological disorders

    Energy Technology Data Exchange (ETDEWEB)

    Kurek, Nicholas S.; Chandra, Sathees B., E-mail: schandra@roosevelt.edu [Department of Biological, Chemical and Physical Sciences, Roosevelt University, Chicago, IL (United States)

    2012-07-01

    Nanotechnology involves probing and manipulating matter at the molecular level. Nanotechnology based molecular diagnostics have the potential to alleviate the suffering caused by many diseases, including neurological disorders, due to the unique properties of nanomaterials. Most neurological illnesses are multifactorial conditions and many of these are also classified as neurobehavioral disorders. Alzheimer's disease, Parkinson's disease, Huntington disease, cerebral ischemia, epilepsy, schizophrenia and autism spectrum disorders like Rett syndrome are some examples of neurological disorders that could be better treated, diagnosed, prevented and possibly cured using nanotechnology. In order to improve the quality of life for disease afflicted people, a wide range of nanomaterials that include gold and silica nanoparticles, quantum dots and DNA along with countless other forms of nanotechnology have been investigated regarding their usefulness in advancing molecular diagnostics. Other small scaled materials like viruses and proteins also have potential for use as molecular diagnostic tools. Information obtained from nanotechnology based diagnostics can be stored and manipulated using bioinformatics software. More advanced nanotechnology based diagnostic procedures for the acquisition of even greater proteomic and genomic knowledge can then be developed along with better ways to fight various diseases. Nanotechnology also has numerous applications besides those related to biotechnology and medicine. In this article, we will discuss and analyze many novel nanotechnology based diagnostic techniques at our disposal today. (author)

  18. Study of methodology diversification in diagnostics

    International Nuclear Information System (INIS)

    Suda, Kazunori; Yonekawa, Tsuyoshi; Yoshikawa, Shinji; Hasegawa, Makoto

    1999-03-01

    There are several research activities to enhance safety and reliability of nuclear power plant operation and maintenance. We are developing a concept of an autonomous operation system where the role of operators is replaced with artificial intelligence. The purpose of the study described in this report is to develop a operator support system in abnormal plant situations. Conventionally, diagnostic modules based on individual methodology such as expert system have been developed and verified. In this report, methodology diversification is considered to integrate diagnostic modules which performance are confirmed using information processing technique. Technical issues to be considered in diagnostic methodology diversification are; 1)reliability of input data, 2)diversification of knowledge models, algorithms and reasoning schemes, 3)mutual complement and robustness. The diagnostic module utilizing the different approaches defined along with strategy of diversification was evaluated using fast breeder plant simulator. As a result, we confirmed that any singular diagnostic module can not meet accuracy criteria for the entire set of anomaly events. In contrast with this, we confirmed that every abnormality could be precisely diagnosed by a mutual combination. In other words, legitimacy of approach selected by strategy of diversification was shown, and methodology diversification attained clear efficiency for abnormal diagnosis. It has been also confirmed that the diversified diagnostic system implemented in this study is able to maintain its accuracy even in case that encountered scale of abnormality is different from reference cases embedded in the knowledge base. (author)

  19. Nanotechnology based diagnostics for neurological disorders

    International Nuclear Information System (INIS)

    Kurek, Nicholas S.; Chandra, Sathees B.

    2012-01-01

    Nanotechnology involves probing and manipulating matter at the molecular level. Nanotechnology based molecular diagnostics have the potential to alleviate the suffering caused by many diseases, including neurological disorders, due to the unique properties of nanomaterials. Most neurological illnesses are multifactorial conditions and many of these are also classified as neurobehavioral disorders. Alzheimer's disease, Parkinson's disease, Huntington disease, cerebral ischemia, epilepsy, schizophrenia and autism spectrum disorders like Rett syndrome are some examples of neurological disorders that could be better treated, diagnosed, prevented and possibly cured using nanotechnology. In order to improve the quality of life for disease afflicted people, a wide range of nanomaterials that include gold and silica nanoparticles, quantum dots and DNA along with countless other forms of nanotechnology have been investigated regarding their usefulness in advancing molecular diagnostics. Other small scaled materials like viruses and proteins also have potential for use as molecular diagnostic tools. Information obtained from nanotechnology based diagnostics can be stored and manipulated using bioinformatics software. More advanced nanotechnology based diagnostic procedures for the acquisition of even greater proteomic and genomic knowledge can then be developed along with better ways to fight various diseases. Nanotechnology also has numerous applications besides those related to biotechnology and medicine. In this article, we will discuss and analyze many novel nanotechnology based diagnostic techniques at our disposal today. (author)

  20. Diagnostics developments and applications for laser fusion experiments

    International Nuclear Information System (INIS)

    Coleman, L.W.

    1977-01-01

    Some diagnostics techniques applied to current laser fusion target experiments are reviewed. Specifically, holographic interferometry of target plasmas, coded aperture imaging of thermonuclear alpha-particles and neutron energy spectrum measurements are discussed

  1. Simultaneous Temperature and Velocity Diagnostic for Reacting Flows, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — A diagnostic technique is proposed for measuring temperature and velocity simultaneously in a high temperature reacting flow for aiding research in propulsion. The...

  2. Advancements of microwave diagnostics in magnetically confined plasmas

    NARCIS (Netherlands)

    Mase, A.; Kogi, Y.; Ito, N.; Yokota, Y.; Akaki, K.; Kawahata, K.; Nagayama, Y.; Tokuzawa, T.; Yamaguchi, S.; Hojo, H.; Oyama, N.; N C Luhmann Jr.,; Park, H. K.; Donne, A. J. H.

    2009-01-01

    Microwave to millimeter-wave diagnostic techniques such as interferometry, reflectometry, scattering and radiometry have been powerful tools for diagnosing magnetically confined plasmas. Recent advances in electronic devices and components together with computer technology have enabled the

  3. Diagnostic imaging in medicine. 2. ed.

    International Nuclear Information System (INIS)

    Reba, R.C.; Goodenough, D.J.

    1984-01-01

    This book describes to practitioners the evolutionary progression of new non-invasive diagnostic imaging techniques. The utility of the procedures is also described in a series of state-of-the-art lectures given by outstanding international clinical investigators from NATO countries. Subjects of the papers include the following: advances in source and detector technology, acoustical imaging, NMR and microwave imaging, positron and single photon emission tomography, digital radiography and image processing and display techniques. Fundamental papers describing the theory of non-invasive procedures are included along with papers describing clinical examinations. Examples of utility and studies of diseases of the abdomen and pelvis, heart and lung, and central nervous system are included. Cost-effective and cost-benefit assessment of the new high technology procedures, as well as the use of diagnostic imaging techniques in developing countries are also presented. An index of leading topics completes the volume. (orig.)

  4. Diagnostic imaging in medicine. 2nd ed

    Energy Technology Data Exchange (ETDEWEB)

    Reba, R C; Goodenough, D J; Davidson, H F

    1984-01-01

    This book describes to practitioners the evolutionary progression of new non-invasive diagnostic imaging techniques. The utility of the procedures is also described in a series of state-of-the-art lectures given by outstanding international clinical investigators from NATO countries. Subjects of the papers include the following: advances in source and detector technology, acoustical imaging, NMR and microwave imaging, positron and single photon emission tomography, digital radiography and image processing and display techniques. Fundamental papers describing the theory of non-invasive procedures are included along with papers describing clinical examinations. Examples of utility and studies of diseases of the abdomen and pelvis, heart and lung, and central nervous system are included. Cost-effective and cost-benefit assessment of the new high technology procedures, as well as the use of diagnostic imaging techniques in developing countries are also presented. An index of leading topics completes the volume.

  5. Techniques and indications in radiology

    International Nuclear Information System (INIS)

    Lange, S.

    1987-01-01

    The stated purpose of this book is to review modern radiologic diagnostic techniques as applied to the study of the kidney and urinary tract, and their pertinent indications. This goal is partially accomplished in the first two segments of the book, which consist of about 100 pages. These include a synoptic description of various techniques - including classic uroradiologic studies such as excretory urography and retrograde pyelography, plus sonography, computed tomography, angiography, and nuclear medicine. The diagnostic signs and the differential diagnoses are fairly well described, aided by a profusion of tables and diagrams. The overall quality of the reproduction of the illustrations is good

  6. Radiological diagnostic in acute chest pain

    International Nuclear Information System (INIS)

    Kawel, Nadine; Bremerich, Jens

    2010-01-01

    Acute chest pain is one of the main symptoms leading to a consultation of the emergency department. Main task of the initial diagnostic is the confirmation or exclusion of a potentially life threatening cause. Conventional chest X-ray and computed tomography are the most significant techniques. Due to limited availability and long examination times magnetic resonance tomography rather plays a limited role in routine clinical workup. In the following paper we will systematically review the radiological diagnostic of the acute life threatening causes of chest pain. Imaging modalities, technical aspects and image interpretation will be discussed. (orig.)

  7. Child abuse. Diagnostic imaging of skeletal injuries

    International Nuclear Information System (INIS)

    Stenzel, Martin; Mentzel, Hans-Joachim

    2012-01-01

    Diagnostic imaging, besides medical history and clinical examination, is a major component in assessment of cases of suspected physical child abuse. Performance of proper imaging technique, and knowledge of specific injury patterns is required for accurate image interpretation by the radiologist, and serves protection of the child in case of proven abuse. On the other side, it is essential to protect the family in unjustified accusations. The reader will be familiarised with essentials of the topic 'Physical child abuse', in order to be able to correctly assess quality, completeness, and results of X-ray films. Moreover, opportunities and limitations of alternative diagnostic modalities will be discussed. (orig.)

  8. Diagnostic Devices for Isothermal Nucleic Acid Amplification

    Directory of Open Access Journals (Sweden)

    Chia-Chen Chang

    2012-06-01

    Full Text Available Since the development of the polymerase chain reaction (PCR technique, genomic information has been retrievable from lesser amounts of DNA than previously possible. PCR-based amplifications require high-precision instruments to perform temperature cycling reactions; further, they are cumbersome for routine clinical use. However, the use of isothermal approaches can eliminate many complications associated with thermocycling. The application of diagnostic devices for isothermal DNA amplification has recently been studied extensively. In this paper, we describe the basic concepts of several isothermal amplification approaches and review recent progress in diagnostic device development.

  9. Diagnostic devices for isothermal nucleic acid amplification.

    Science.gov (United States)

    Chang, Chia-Chen; Chen, Chien-Cheng; Wei, Shih-Chung; Lu, Hui-Hsin; Liang, Yang-Hung; Lin, Chii-Wann

    2012-01-01

    Since the development of the polymerase chain reaction (PCR) technique, genomic information has been retrievable from lesser amounts of DNA than previously possible. PCR-based amplifications require high-precision instruments to perform temperature cycling reactions; further, they are cumbersome for routine clinical use. However, the use of isothermal approaches can eliminate many complications associated with thermocycling. The application of diagnostic devices for isothermal DNA amplification has recently been studied extensively. In this paper, we describe the basic concepts of several isothermal amplification approaches and review recent progress in diagnostic device development.

  10. Optical diagnostics of atmospheric pressure air plasmas

    International Nuclear Information System (INIS)

    Laux, C O; Spence, T G; Kruger, C H; Zare, R N

    2003-01-01

    Atmospheric pressure air plasmas are often thought to be in local thermodynamic equilibrium owing to fast interspecies collisional exchange at high pressure. This assumption cannot be relied upon, particularly with respect to optical diagnostics. Velocity gradients in flowing plasmas and/or elevated electron temperatures created by electrical discharges can result in large departures from chemical and thermal equilibrium. This paper reviews diagnostic techniques based on optical emission spectroscopy and cavity ring-down spectroscopy that we have found useful for making temperature and concentration measurements in atmospheric pressure plasmas under conditions ranging from thermal and chemical equilibrium to thermochemical nonequilibrium

  11. Diagnostic molecular microbiology: a 2013 snapshot.

    Science.gov (United States)

    Fairfax, Marilynn Ransom; Salimnia, Hossein

    2013-12-01

    Molecular testing has a large and increasing role in the diagnosis of infectious diseases. It has evolved significantly since the first probe tests were FDA approved in the early 1990s. This article highlights the uses of molecular techniques in diagnostic microbiology, including "older," as well as innovative, probe techniques, qualitative and quantitative RT-PCR, highly multiplexed PCR panels, some of which use sealed microfluidic test cartridges, MALDI TOF, and nuclear magnetic resonance. Tests are grouped together by technique and target. Tests with similar roles for similar analytes are compared with respect to benefits, drawbacks, and possible problems. Copyright © 2013 Elsevier Inc. All rights reserved.

  12. Diagnostics for high-brightness beams

    International Nuclear Information System (INIS)

    Shafer, R.E.

    1990-01-01

    Special techniques are required for beam diagnostics on high-brightness particle beams. Examples of high-brightness beams include low-emittance proton linacs (either pulsed or CW), electron linacs suitable for free-electron-laser applications, and future linear colliders. Non-interceptive and minimally-interceptive techniques for measuring beam current, position, profile, and transverse and longitudinal emittance will be reviewed. Included will be stripline, wire scanner, laser neutralization, beam-beam scattering, interceptive microgratings, spontaneous emission, optical transition radiation, and other techniques. 24 refs

  13. Experimental Investigation on Admittance-Based Piezoelectric Sensor Diagnostic Process

    Energy Technology Data Exchange (ETDEWEB)

    Jo, Hyejin; Park, Tongil; Park, Gyuhae [Chonnam National University, Gwangju (Korea, Republic of)

    2015-01-15

    Structural health monitoring (SHM) techniques based on the use of active-sensing piezoelectric (PZT) materials have received considerable attention. The validation of the PZT functionality during SHM operation is critical to successfully implementing a reliable SHM system. In this study, we investigated several parameters that affect the admittance-based sensor diagnostic process. We experimentally identified the temperature dependency of the active-sensor diagnostic process. We found that the admittance-based sensor diagnostic process can differentiate the adhesion conditions of bonding materials that are used to install a PZT on a structure, which is important when designing a sensor diagnostic process for an SHM system.

  14. Radiogenomics: Creating a link between molecular diagnostics and diagnostic imaging

    Energy Technology Data Exchange (ETDEWEB)

    Rutman, Aaron M. [Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92103 (United States); Kuo, Michael D. [Department of Radiology, University of California San Diego Medical Center, San Diego, CA 92103 (United States); Center for Translational Medical Systems, University of California San Diego Medical Center, San Diego, CA 92103 (United States)], E-mail: mkuo@ucsd.edu

    2009-05-15

    Studies employing high-throughput biological techniques have recently contributed to an improved characterization of human cancers, allowing for novel sub-classification, better diagnostic accuracy, and more precise prognostication. However, requirement of surgical procurement of tissue among other things limits the clinical application of such methods in everyday patient care. Radiographic imaging is routine in clinical practice but is currently histopathology based. The use of routine radiographic imaging provides a potential platform for linking specific imaging traits with specific gene expression patterns that inform the underlying cellular pathophysiology; imaging features could then serve as molecular surrogates that contribute to the diagnosis, prognosis, and likely gene-expression-associated treatment response of various forms of human cancer. This review focuses on high-throughput methods such as microarray analysis of gene expression, their role in cancer research, and in particular, on novel methods of associating gene expression patterns with radiographic imaging phenotypes, known as 'radiogenomics.' These findings underline a potential future role of both diagnostic and interventional radiologists in genetic assessment of cancer patients with radiographic imaging studies.

  15. Radiogenomics: Creating a link between molecular diagnostics and diagnostic imaging

    International Nuclear Information System (INIS)

    Rutman, Aaron M.; Kuo, Michael D.

    2009-01-01

    Studies employing high-throughput biological techniques have recently contributed to an improved characterization of human cancers, allowing for novel sub-classification, better diagnostic accuracy, and more precise prognostication. However, requirement of surgical procurement of tissue among other things limits the clinical application of such methods in everyday patient care. Radiographic imaging is routine in clinical practice but is currently histopathology based. The use of routine radiographic imaging provides a potential platform for linking specific imaging traits with specific gene expression patterns that inform the underlying cellular pathophysiology; imaging features could then serve as molecular surrogates that contribute to the diagnosis, prognosis, and likely gene-expression-associated treatment response of various forms of human cancer. This review focuses on high-throughput methods such as microarray analysis of gene expression, their role in cancer research, and in particular, on novel methods of associating gene expression patterns with radiographic imaging phenotypes, known as 'radiogenomics.' These findings underline a potential future role of both diagnostic and interventional radiologists in genetic assessment of cancer patients with radiographic imaging studies.

  16. Electron Bunch Length Diagnostic With Coherent Smith-Purcell Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Nguyen, D.C.

    1997-05-12

    The authors have designed a new technique for measuring subpicosecond electron bunch lengths using coherent Smith-Purcell radiation. This new diagnostic technique involves passing the electron beam in close proximity of a grating with a period comparable to the electron bunch length. The emitted Smith-Purcell radiation will have a coherent component whose angular position and distribution are directly related to the electron bunch length and longitudinal profile, respectively. This new diagnostic technique is inherently simple, inexpensive and non-intercepting. The authors show that the new technique is also scaleable to femtosecond regime.

  17. Electron Bunch Length Diagnostic With Coherent Smith-Purcell Radiation

    International Nuclear Information System (INIS)

    Nguyen, D.C.

    1997-01-01

    The authors have designed a new technique for measuring subpicosecond electron bunch lengths using coherent Smith-Purcell radiation. This new diagnostic technique involves passing the electron beam in close proximity of a grating with a period comparable to the electron bunch length. The emitted Smith-Purcell radiation will have a coherent component whose angular position and distribution are directly related to the electron bunch length and longitudinal profile, respectively. This new diagnostic technique is inherently simple, inexpensive and non-intercepting. The authors show that the new technique is also scaleable to femtosecond regime

  18. LHD neutron diagnostics

    International Nuclear Information System (INIS)

    Isobe, M.; Ogawa, K.; Kobuchi, T.

    2015-01-01

    The Large Helical Device (LHD) project will step into a next stage, i.e. experiment by using deuterium gases after two years of preparation. A comprehensive set of neutron and γ-ray diagnostics is going to be installed on the LHD towards extension of energetic-particle (EP) physics research in heliotron plasmas. Conceptual design of fusion products diagnostics for the LHD was made in late 1990s. After conclusion of agreements for the LHD deuterium experiment with local government bodies, development of FPs diagnostics has begun lately. Because there are a lot of tasks to do, all Japan fusion neutron and γ-ray diagnostics team has been organized in the collaboration framework of National Institute for Fusion Science. FPs diagnostics system on the LHD will consist of 1) wide dynamic range neutron flux monitor (NFM), 2) neutron activation system (NAS), 3) vertical neutron camera (VNC). In addition to these, we are developing a directional scintillating fiber detector, an artificial diamond detector and a γ-ray scintillation detector for confinement study of MeV ions. A neutron energy spectrometer prototype is also being developed and tested in KSTAR. In this paper, roles of NFM, NAS and VNC and current status of implementation onto the LHD are briefly described. (author)

  19. Plasma diagnostics for tokamaks and stellarators. Proceedings of the IV Course and Workshop on Magnetic Confinement Fusion. UIMP Santander (Spain), June 1992

    International Nuclear Information System (INIS)

    Stott, P. E.; Sanchez, J.

    1994-01-01

    A collection of papers on plasma diagnostics is presented. The papers show the state of the art developments in a series of techniques: Magnetic diagnostics, Edge diagnostics, Langmuir probes, Spectroscopy, Microwave and FIR diagnostics as well as Thomson Scattering. Special interest was focused on those diagnostics oriented to fluctuations measurements in the plasma. (Author) 451 refs

  20. Data needs for diagnostics of low pressure plasmas

    International Nuclear Information System (INIS)

    Graham, Bill

    2000-01-01

    The low pressure plasma processing environment is complex and presents many diagnostic challenges. Here the diagnostic techniques used for accurate and detailed measurement of the density and energy distributions of charged and neutral species are reviewed. Most of the techniques rely heavily on atomic and molecular data. The specific data needs of each diagnostic are outlined. It is shown that in total these data needs are vast and diverse and cannot all be met from specific measurements or calculations. The real need is for generic scaling rules for each of the significant atomic and molecular processes

  1. The role of diagnostic radiology in compressive and entrapment neuropathies

    International Nuclear Information System (INIS)

    Spratt, J.D.; Stanley, A.J.; Hide, I.G.; Campbell, R.S.D.; Grainger, A.J.

    2002-01-01

    Diagnostic imaging is increasingly being utilised to aid the diagnosis of compression and entrapment neuropathies. Cross-sectional imaging, primarily ultrasound and magnetic resonance imaging, can provide exquisite anatomical detail of peripheral nerves and the changes that may occur as a result of compression. Imaging can provide a useful diagnostic aid to clinicians, which may supplement clinical evaluation, and may eventually provide an alternative to other diagnostic techniques such as nerve conduction studies. This article describes the abnormalities that may be demonstrated by current imaging techniques, and critically analyses the impact of imaging in diagnosis of peripheral compressive neuropathy. (orig.)

  2. The role of diagnostic radiology in compressive and entrapment neuropathies

    Energy Technology Data Exchange (ETDEWEB)

    Spratt, J.D.; Stanley, A.J.; Hide, I.G.; Campbell, R.S.D. [Department of Radiology, James Cook University Hospital, Middlesbrough, TS4 3BW (United Kingdom); Grainger, A.J. [Department of Radiology, Leeds General Infirmary, Leeds (United Kingdom)

    2002-09-01

    Diagnostic imaging is increasingly being utilised to aid the diagnosis of compression and entrapment neuropathies. Cross-sectional imaging, primarily ultrasound and magnetic resonance imaging, can provide exquisite anatomical detail of peripheral nerves and the changes that may occur as a result of compression. Imaging can provide a useful diagnostic aid to clinicians, which may supplement clinical evaluation, and may eventually provide an alternative to other diagnostic techniques such as nerve conduction studies. This article describes the abnormalities that may be demonstrated by current imaging techniques, and critically analyses the impact of imaging in diagnosis of peripheral compressive neuropathy. (orig.)

  3. Diagnostic double guarded low-volume uterine lavage in mares

    DEFF Research Database (Denmark)

    Christoffersen, Mette; Brandis, Louise; Samuelsson, Julia

    2014-01-01

    Endometritis constitutes a major problem in the management of broodmares; hence diagnostic tests with a high sensitivity and specificity are desired. We hypothesize that a double guarded uterine flush technique for bacterial culture and cytology is comparable to standard diagnostic tests, the end......Endometritis constitutes a major problem in the management of broodmares; hence diagnostic tests with a high sensitivity and specificity are desired. We hypothesize that a double guarded uterine flush technique for bacterial culture and cytology is comparable to standard diagnostic tests...... (lavage: 11%, swab: 8%, biopsy: 7%) (positive bacterial growth > 4 Colony forming units (CFU)). Positive cytology was less likely to occur when E. coli was isolated from the diagnostic tests compared to the growth of β-hemolytic streptococci. Isolation of pathogens from uterine samples was highly...

  4. Polychromatic holographic plasma diagnostics

    International Nuclear Information System (INIS)

    Zhiglinskij, A.G.; Morozov, A.O.

    1992-01-01

    Review of holographic interferometry properties is performed and advantages of this method by plasma diagnostics are indicated. Main results obtained by the method of holographic interferometry in studies of various-type plasmas are considered. Special attention is paid to multiwave plasma diagnostics, the necessity of which is related as a rule to multicomponent composition of plasma. The eight laser and gas-discharge sources and holographic schemes, which make it possible to realize plasma polychromatic and holographic interferometry, are considered. The advantages of the method are demonstrated by examples of polychromatic holographic diagnostics of arc discharge and discharge in a hollow cathode. Review of theoretical works determining the applicability area of resonance polychromatic interferometry is carried out

  5. Reversed field pinch diagnostics

    International Nuclear Information System (INIS)

    Weber, P.G.

    1986-01-01

    The Reversed Field Pinch (RFP) is a toroidal, axisymmetric magnetic confinement configuration characterized by a magnetic field configuration in which the toroidal magnetic field is of similar strength to the poloidal field, and is reversed at the edge compared to the center. The RFP routinely operates at high beta, and is a strong candidate for a compact fusion device. Relevant attributes of the configuration will be presented, together with an overview of present and planned experiments and their diagnostics. RFP diagnostics are in many ways similar to those of other magnetic confinement devices (such as tokamaks); these lectures will point out pertinent differences, and will present some diagnostics which provide special insights into unique attributes of the RFP

  6. Corpuscular plasma diagnostics

    International Nuclear Information System (INIS)

    Afrosimov, V.; Petrov, M.

    1984-01-01

    An elementary explanation is presented of the physical principles and important methods of corpuscular plasma diagnostics. The invaluable role of corpuscular methods for measuring the hot plasma ion component in thermonuclear facilities, especially hydrogen ions in tokamaks, is emphasized. All corpuscular methods employ analysis of fast neutral atoms and therefore the mechanism of their creation inside a hot plasma is explained first. The ammount of information obtainable from spectra of fast neutrals is discussed. Multichannel analyzers developed at the FTI A.F. Ioffe in Leningrad are described in detail. Classical passive corpuscular diagnostics are examined as are active methods using artifitial beams of hydrogen atoms. The method used for obtaining local values of ion temperature and density is explained. Corpuscular spectroscopic diagnostics and its application for measuring impurities is mentioned. (J.U.)

  7. [Cytology in uropathological diagnostics].

    Science.gov (United States)

    Gaisa, N T; Lindemann-Docter, K

    2015-11-01

    Cytology in uropathological diagnostics is mainly performed for oncological purposes. The assessment of malignancy by urothelial cell morphology is therefore decisive; however, cytology is only sensitive enough to detect high-grade tumor cells and the different low-grade tumors cannot be reliably diagnosed. Thus, the four-tier classification system of cytological findings (i.e. negative, atypical cells but significance uncertain, suspicious and positive) refers to high-grade tumor cells only. Furthermore, for valid cytological diagnostics not only the cytological specimen but also clinical information on cystoscopy findings and, if applicable, a biopsy should be evaluated together. In difficult differential diagnostic settings, e.g. differentiation between reactive versus neoplastic atypia or difficult to access lesions in the upper urinary tract, additional fluorescence in situ hybridization of cytological preparations might be helpful. At the moment there are no indications for further immunocytology or additional biomarker tests.

  8. ORION laser target diagnostics

    International Nuclear Information System (INIS)

    Bentley, C. D.; Edwards, R. D.; Andrew, J. E.; James, S. F.; Gardner, M. D.; Comley, A. J.; Vaughan, K.; Horsfield, C. J.; Rubery, M. S.; Rothman, S. D.; Daykin, S.; Masoero, S. J.; Palmer, J. B.; Meadowcroft, A. L.; Williams, B. M.; Gumbrell, E. T.; Fyrth, J. D.; Brown, C. R. D.; Hill, M. P.; Oades, K.

    2012-01-01

    The ORION laser facility is one of the UK's premier laser facilities which became operational at AWE in 2010. Its primary mission is one of stockpile stewardship, ORION will extend the UK's experimental plasma physics capability to the high temperature, high density regime relevant to Atomic Weapons Establishment's (AWE) program. The ORION laser combines ten laser beams operating in the ns regime with two sub ps short pulse chirped pulse amplification beams. This gives the UK a unique combined long pulse/short pulse laser capability which is not only available to AWE personnel but also gives access to our international partners and visiting UK academia. The ORION laser facility is equipped with a comprehensive suite of some 45 diagnostics covering optical, particle, and x-ray diagnostics all able to image the laser target interaction point. This paper focuses on a small selection of these diagnostics.

  9. ORION laser target diagnostics.

    Science.gov (United States)

    Bentley, C D; Edwards, R D; Andrew, J E; James, S F; Gardner, M D; Comley, A J; Vaughan, K; Horsfield, C J; Rubery, M S; Rothman, S D; Daykin, S; Masoero, S J; Palmer, J B; Meadowcroft, A L; Williams, B M; Gumbrell, E T; Fyrth, J D; Brown, C R D; Hill, M P; Oades, K; Wright, M J; Hood, B A; Kemshall, P

    2012-10-01

    The ORION laser facility is one of the UK's premier laser facilities which became operational at AWE in 2010. Its primary mission is one of stockpile stewardship, ORION will extend the UK's experimental plasma physics capability to the high temperature, high density regime relevant to Atomic Weapons Establishment's (AWE) program. The ORION laser combines ten laser beams operating in the ns regime with two sub ps short pulse chirped pulse amplification beams. This gives the UK a unique combined long pulse/short pulse laser capability which is not only available to AWE personnel but also gives access to our international partners and visiting UK academia. The ORION laser facility is equipped with a comprehensive suite of some 45 diagnostics covering optical, particle, and x-ray diagnostics all able to image the laser target interaction point. This paper focuses on a small selection of these diagnostics.

  10. Nova diagnostics summary

    International Nuclear Information System (INIS)

    Slivinsky, V.W.; Drake, R.P.

    1985-01-01

    The authors intend that Nova be the best diagnosed ICF research facility in operation today. The authors experience in providing advanced diagnostics for previous laser systems will be extended at Nova, and will be challenged by the development of new instrumentation to diagnose the more advanced targets made possible by this powerful laser. Previous experience has shown that to understand target performance, the authors must have as complete a set of diagnostics as possible. The Nova diagnostics are divided into two sets: the basic set required for the initial Nova experiments and the more advanced set for later, generally more complex, experiments. The basic set will be operational for the first Nova shots; it was a Nova line item funded with Nova construction money. This basic set is presented in a table

  11. Molecular diagnostics for human leptospirosis.

    Science.gov (United States)

    Waggoner, Jesse J; Pinsky, Benjamin A

    2016-10-01

    The definitive diagnosis of leptospirosis, which results from infection with spirochetes of the genus Leptospira, currently relies on the use of culture, serological testing (microscopic agglutination testing), and molecular detection. The purpose of this review is to describe new molecular diagnostics for Leptospira and discuss advancements in the use of available methods. Efforts have been focused on improving the clinical sensitivity of Leptospira detection using molecular methods. In this review, we describe a reoptimized pathogenic species-specific real-time PCR (targeting lipL32) that has demonstrated improved sensitivity, findings by two groups that real-time reverse-transcription PCR assays targeting the 16S rrs gene can improve detection, and two new loop-mediated amplification techniques. Quantitation of leptospiremia, detection in different specimen types, and the complementary roles played by molecular detection and microscopic agglutination testing will be discussed. Finally, a protocol for Leptospira strain subtyping using variable number tandem repeat targets and high-resolution melting will be described. Molecular diagnostics have an established role for the diagnosis of leptospirosis and provide an actionable diagnosis in the acute setting. The use of real-time reverse-transcription PCR for testing serum/plasma and cerebrospinal fluid, when available, may improve the detection of Leptospira without decreasing clinical specificity.

  12. Diagnostic imaging in fertility disorders

    International Nuclear Information System (INIS)

    Winfield, A.C.; Fleischer, A.C.

    1987-01-01

    Some 10%-15% of married couples are affected by a fertility disorder. The number of infertile couples seeking medical assistance has increased dramatically in the past decade. The roles of diagnostic imaging with radiography and US (conventional and transvaginal) is emphasized in the assessment of couples with fertility disorders and an unexpectedly higher incidence of fetal wastage secondary to unsuspected uterine anomalies. The most frequently utilized radiographic examination in infertile patients is hysterosalpingography (HSG). Techniques and complications of HSG are illustrated. The normal anatomy, variants, and congenital anomalies of the uterus and fallopian tubes are demonstrated, as are the numerous abnormalities such as filling defects of the uterine cavity, synechiae, effects of maternal diethylstilbestrol exposure, inflammatory tubal disease, and the more common HSG findings following uterine and tubal surgery. The role of diagnostic imaging in male infertility, including vasography and varicocele detection, are addressed. Conventional and transvaginal US in the management of gynecologic fertility disorders are examined, with an emphasis on follicular monitoring, guided follicular aspirations, endometrial evaluations, and evaluation of other disorders (such as endometriosis) associated with infertility

  13. Spectroscopic diagnostics of industrial plasmas

    International Nuclear Information System (INIS)

    Joshi, N.K.

    2004-01-01

    Plasmas play key role in modern industry and are being used for processing micro electronic circuits to the destruction of toxic waste. Characterization of industrial plasmas which includes both 'thermal plasmas' and non-equilibrium plasmas or 'cold plasmas' in industrial environment offers quite a challenge. Numerous diagnostic techniques have been developed for the measurement of these partially ionized plasma and/or particulate parameters. The 'simple' non-invasive spectroscopic methods for characterization of industrial plasmas will be discussed in detail in this paper. The excitation temperature in thermal (DC/RF) plasma jets has been determined using atomic Boltzmann technique. The central axis temperature of thermal plasma jets in a spray torch can be determined using modified atomic Boltzmann technique with out using Abel inversion. The Stark broadening of H β and Ar-I (430 nm) lines have been used to determine the electron number density in thermal plasma jets. In low-pressure non-equilibrium argon plasma, electron temperature has been measured using the Corona model from the ratio of line intensities of atomic and ionic transitions. (author)

  14. Diagnostic technology of PWR plant equipment failures

    International Nuclear Information System (INIS)

    Nakamura, Tetsuo; Tanaka, Mamoru; Okamachi, Masao; Taguchi, Shozo; Nagashima, Kazuhiro; Ishikawa, Satoshi

    1985-01-01

    To confirm the soundness of the important facilities in a nuclear power plant contributes to the reliability of the plant operations and improvement of its operation rate. For this purpose, the following diagnostic techniques have been developed. (1). Vibration and loose parts monitoring: Detection of abnormal structural vibrations in the reactor, estimation of its mode, detection of loose parts in the primary system, and estimation of the position and energy of their collisions against the reactor vessel or the like. (2). Valve leak monitoring: Detection of leaks from primary valves in the primary cooling boundary, such as the pressurizer relief valve and safety valve, and estimation of the form of the leaks. (3). Detector noise response diagnosis: Diagnosis of degradation of principal process detectors during plant operation. Furthermore, a diagnostic system incorporating the above diagnostic technology applicable to actual plants has been experimentally manufactured and successfully verified. (author)

  15. Methodology, models and algorithms in thermographic diagnostics

    CERN Document Server

    Živčák, Jozef; Madarász, Ladislav; Rudas, Imre J

    2013-01-01

    This book presents  the methodology and techniques of  thermographic applications with focus primarily on medical thermography implemented for parametrizing the diagnostics of the human body. The first part of the book describes the basics of infrared thermography, the possibilities of thermographic diagnostics and the physical nature of thermography. The second half includes tools of intelligent engineering applied for the solving of selected applications and projects. Thermographic diagnostics was applied to problematics of paraplegia and tetraplegia and carpal tunnel syndrome (CTS). The results of the research activities were created with the cooperation of the four projects within the Ministry of Education, Science, Research and Sport of the Slovak Republic entitled Digital control of complex systems with two degrees of freedom, Progressive methods of education in the area of control and modeling of complex object oriented systems on aircraft turbocompressor engines, Center for research of control of te...

  16. Residual heat removal system diagnostic advisor

    International Nuclear Information System (INIS)

    Tripp, L.

    1991-01-01

    This paper reports on the Residual Heat Removal System (RHRS) Diagnostic Advisor which is an expert system designed to alert the operators to abnormal conditions that exits in the RHRS and offer advice about the cause of the abnormal conditions. The Advisor uses a combination of rule-based and model-based diagnostic techniques to perform its functions. This diagnostic approach leads to a deeper understanding of the RHRS by the Advisor and consequently makes it more robust to unexpected conditions. The main window of the interactive graphic display is a schematic diagram of the RHRS piping system. When a conclusion about a failed component can be reached, the operator can bring up windows that describe the failure mode of the component and a brief explanation about how the Advisor arrived at its conclusion

  17. Beam Instrumentation and Diagnostics

    CERN Document Server

    Strehl, Peter

    2006-01-01

    This treatise covers all aspects of the design and the daily operations of a beam diagnostic system for a large particle accelerator. A very interdisciplinary field, it involves contributions from physicists, electrical and mechanical engineers and computer experts alike so as to satisfy the ever-increasing demands for beam parameter variability for a vast range of operation modi and particles. The author draws upon 40 years of research and work, most of them spent as the head of the beam diagnostics group at GSI. He has illustrated the more theoretical aspects with many real-life examples that will provide beam instrumentation designers with ideas and tools for their work.

  18. Diagnostic Imaging Workshop

    International Nuclear Information System (INIS)

    Sociedad Argentina de Fisica Medica

    2012-01-01

    The American Association of Physicist in Medicine (AAPM), the International Organization for Medical Physics (IOMP) and the Argentina Society of Medical Physics (SAFIM) was organized the Diagnostic Imaging Workshop 2012, in the city of Buenos Aires, Argentina. This workshop was an oriented training and scientific exchange between professionals and technicians who work in medical physics, especially in the areas of diagnostic imaging, nuclear medicine and radiotherapy, with special emphasis on the use of multimodal imaging for radiation treatment, planning as well of quality assurance associates.

  19. Diagnostic Management of Pancreatic Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Dabizzi, Emanuele [Division of Gastroenterology and Hepatology, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, Florida 32224 (United States); Assef, Mauricio Saab [Faculdade de Ciências Médicas da Santa Casa de São Paulo, Rua Dr. Cesário Motta Jr. #61 Cep: 01221-020, São Paulo (Brazil); Raimondo, Massimo, E-mail: raimondo.massimo@mayo.edu [Division of Gastroenterology and Hepatology, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, Florida 32224 (United States)

    2011-01-31

    Pancreatic cancer is one of the most deadly solid tumors, with an overall 5-year survival rate of less than 5%. Due to a non-specific clinical presentation, it is often diagnosed at an advanced stage and is rarely amenable for curative treatment. Therefore early diagnosis and appropriate staging are still essential to define the best care and to improve patient survival. Several imaging modalities are currently available for the evaluation of pancreatic cancer. This review focuses on different techniques and discusses the diagnostic management of patients with pancreatic cancer. This review was conducted utilizing Pubmed and was limited to papers published within the last 5 years. The search key words pancreatic cancer, pancreatic adenocarcinoma, pancreatic tumors, diagnosis, radiology, imaging, nuclear imaging, endoscopy, endoscopic ultrasound and biochemical markers were used.

  20. Diagnostic Management of Pancreatic Cancer

    International Nuclear Information System (INIS)

    Dabizzi, Emanuele; Assef, Mauricio Saab; Raimondo, Massimo

    2011-01-01

    Pancreatic cancer is one of the most deadly solid tumors, with an overall 5-year survival rate of less than 5%. Due to a non-specific clinical presentation, it is often diagnosed at an advanced stage and is rarely amenable for curative treatment. Therefore early diagnosis and appropriate staging are still essential to define the best care and to improve patient survival. Several imaging modalities are currently available for the evaluation of pancreatic cancer. This review focuses on different techniques and discusses the diagnostic management of patients with pancreatic cancer. This review was conducted utilizing Pubmed and was limited to papers published within the last 5 years. The search key words pancreatic cancer, pancreatic adenocarcinoma, pancreatic tumors, diagnosis, radiology, imaging, nuclear imaging, endoscopy, endoscopic ultrasound and biochemical markers were used

  1. Nuclear medicine in bone diagnostics

    International Nuclear Information System (INIS)

    Feine, U.; Mueller-Schauenburg, W.

    1985-01-01

    This book on nuclear medicine in bone diagnostics and other complementary imaging methods is composed out of the 51 presentations of the 2nd Tuebinger bone symposium held on the 11th and 12th January 1985; it gives an overview of newer methods of nuclear medicine and other imaging methods such as magnetic-resonance tomography and sonography. While the 1st Tuebinger Symposium in January 1981 dealt with the clinical application of classical bone scintigraphy and the possibilities of the results of differential diagnosis, the present book is concerned with indications, alternative radiopharmaceuticals for skeleton scintigraphy and other techniques. The intention is to give a survey of the developments made over the last few years. (orig./MG) [de

  2. Automated diagnostics scoping study. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Quadrel, R.W.; Lash, T.A.

    1994-06-01

    The objective of the Automated Diagnostics Scoping Study was to investigate the needs for diagnostics in building operation and to examine some of the current technologies in automated diagnostics that can address these needs. The study was conducted in two parts. In the needs analysis, the authors interviewed facility managers and engineers at five building sites. In the technology survey, they collected published information on automated diagnostic technologies in commercial and military applications as well as on technologies currently under research. The following describe key areas that the authors identify for the research, development, and deployment of automated diagnostic technologies: tools and techniques to aid diagnosis during building commissioning, especially those that address issues arising from integrating building systems and diagnosing multiple simultaneous faults; technologies to aid diagnosis for systems and components that are unmonitored or unalarmed; automated capabilities to assist cause-and-effect exploration during diagnosis; inexpensive, reliable sensors, especially those that expand the current range of sensory input; technologies that aid predictive diagnosis through trend analysis; integration of simulation and optimization tools with building automation systems to optimize control strategies and energy performance; integration of diagnostic, control, and preventive maintenance technologies. By relating existing technologies to perceived and actual needs, the authors reached some conclusions about the opportunities for automated diagnostics in building operation. Some of a building operator`s needs can be satisfied by off-the-shelf hardware and software. Other needs are not so easily satisfied, suggesting directions for future research. Their conclusions and suggestions are offered in the final section of this study.

  3. Electron beam diagnostics study

    International Nuclear Information System (INIS)

    Garganne, P.

    1989-08-01

    This paper summarizes the results of a study on beam diagnostics, using carbon wire scanners and optical transition radiation (DTR) monitors. The main consideration consists in the material selection, taking their thermal properties and their effect on the beam into account [fr

  4. Molecular Beacons in Diagnostics

    OpenAIRE

    Tyagi, Sanjay; Kramer, Fred Russell

    2012-01-01

    Recent technical advances have begun to realize the potential of molecular beacons to test for diverse infections in clinical diagnostic laboratories. These include the ability to test for, and quantify, multiple pathogens in the same clinical sample, and to detect antibiotic resistant strains within hours. The design principles of molecular beacons have also spawned a variety of allied technologies.

  5. Diagnostic radiation and pregnancy

    International Nuclear Information System (INIS)

    Collins, L.; Fitzgerald, P.

    1983-01-01

    Accidental irradiation of the embryo or fetus in the first trimester is a problem which will occasionally occur. The value of a proper estimation of the radiation dose is emphasised. Very rarely does a single diagnostic procedure result in a uterine dose as high as 50 mGy. An accidental irradiation should rarely be cause for termination of a pregnancy

  6. 1968 Prototype Diagnostic Test.

    Science.gov (United States)

    Veterans Administration Hospital, Bedford, MA.

    This true-false diagnostic test was used for pretesting of employees at a Veterans Administration Hospital. The test is comprised of 20 items. An alternate test--Classification Questionnaire--was used for testing after remedial training. (For related document, see TM 002 334.) (DB)

  7. It's diagnostics, stupid.

    Science.gov (United States)

    Bernards, René

    2010-04-02

    To stem the spiraling cost of cancer treatment, a concerted effort is urgently needed to develop molecular diagnostics to better identify the patients that respond to expensive targeted therapies. Opportunities and obstacles in the development of such drug response biomarkers are discussed here. Copyright 2010 Elsevier Inc. All rights reserved.

  8. Diagnostics for pellet experiments

    International Nuclear Information System (INIS)

    Johnson, R.R.

    1978-01-01

    The target diagnostics which are being used and planned in current laser driven ICF Experiments are described. Most of these diagnostics can be easily applied to future ion-beam fusion experiments. The status of laser fusion diagnostics has been much improved in the last 5 years and further improvements can be expected and should be available when the first ICF experiments using ion beams are performed. As an example, x-ray temporal and spatial resolutions are now approximately 5 psec and 3 μm, which is approximately a factor of 4 better than the resolution reported in the first implosion experiments. As one plans ahead for ion-beam fusion experiments it should be emphasized that high yield experiments are easier to diagnose provided adequate shielding is employed. However, in the event that the first high yield experiments fail it will be necessary to have diagnostics available to determine where the problems lie. In laser fusion it is interesting to note that higher laser powers are required now for breakeven experiments than first anticipated, mainly because some aspects of the laser-interaction physics were not recognized until the experiments were carefully diagnosed. Thus as has been pointed out, it may be necessary to increase the energy of the ion-beam driver to enable us to do breakeven experiments with high confidence

  9. Serbia : Systematic Country Diagnostic

    OpenAIRE

    World Bank Group

    2015-01-01

    This Systematic Country Diagnostic (SCD) aims to identify the major constraints on and opportunities for sustaining poverty reduction and shared prosperity in Serbia. The SCD serves as the analytic foundation on which the World Bank Group and the Government of Serbia will define a new Country Partnership Framework for FY2016 to FY2020. It is based on the best possible analysis, drawing on ...

  10. Diagnostic and interventional radiology

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, Thomas J. [Klinikum der Johann Wolfgang Goethe-Universitaet, Frankfurt am Main (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie; Reith, Wolfgang [Universitaetsklinikum des Saarlandes, Homburg/Saar (Germany). Klinik fuer Diagnostische und Interventionelle Neuroradiologie; Rummeny, Ernst J. (ed.) [Technische Univ. Muenchen Klinikum rechts der Isar, Muenchen (Germany). Inst. fuer Radiologie

    2016-08-01

    This exceptional book covers all aspects of diagnostic and interventional radiology within one volume, at a level appropriate for the specialist. From the basics through diagnosis to intervention: the reader will find a complete overview of all areas of radiology. The clear, uniform structure, with chapters organized according to organ system, facilitates the rapid retrieval of information. Features include: Presentation of the normal radiological anatomy Classification of the different imaging procedures according to their diagnostic relevance Imaging diagnosis with many reference images Precise description of the interventional options The inclusion of many instructive aids will be of particular value to novices in decision making: Important take home messages and summaries of key radiological findings smooth the path through the jungle of facts Numerous tables on differential diagnosis and typical findings in the most common diseases offer a rapid overview and orientation Diagnostic flow charts outline the sequence of diagnostic evaluation All standard procedures within the field of interventional radiology are presented in a clinically relevant and readily understandable way, with an abundance of illustrations. This is a textbook, atlas, and reference in one: with more than 2500 images for comparison with the reader's own findings. This comprehensive and totally up-to-date book provides a superb overview of everything that the radiology specialist of today needs to know.

  11. Study for the design method of multi-agent diagnostic system to improve diagnostic performance for similar abnormality

    International Nuclear Information System (INIS)

    Minowa, Hirotsugu; Gofuku, Akio

    2014-01-01

    Accidents on industrial plants cause large loss on human, economic, social credibility. In recent, studies of diagnostic methods using techniques of machine learning such as support vector machine is expected to detect the occurrence of abnormality in a plant early and correctly. There were reported that these diagnostic machines has high accuracy to diagnose the operating state of industrial plant under mono abnormality occurrence. But the each diagnostic machine on the multi-agent diagnostic system may misdiagnose similar abnormalities as a same abnormality if abnormalities to diagnose increases. That causes that a single diagnostic machine may show higher diagnostic performance than one of multi-agent diagnostic system because decision-making considering with misdiagnosis is difficult. Therefore, we study the design method for multi-agent diagnostic system to diagnose similar abnormality correctly. This method aimed to realize automatic generation of diagnostic system where the generation process and location of diagnostic machines are optimized to diagnose correctly the similar abnormalities which are evaluated from the similarity of process signals by statistical method. This paper explains our design method and reports the result evaluated our method applied to the process data of the fast-breeder reactor Monju

  12. Tune-Based Halo Diagnostics

    International Nuclear Information System (INIS)

    Cameron, Peter

    2003-01-01

    Tune-based halo diagnostics can be divided into two categories -- diagnostics for halo prevention, and diagnostics for halo measurement. Diagnostics for halo prevention are standard fare in accumulators, synchrotrons, and storage rings, and again can be divided into two categories -- diagnostics to measure the tune distribution (primarily to avoid resonances), and diagnostics to identify instabilities (which will not be discussed here). These diagnostic systems include kicked (coherent) tune measurement, phase-locked loop (PLL) tune measurement, Schottky tune measurement, beam transfer function (BTF) measurements, and measurement of transverse quadrupole mode envelope oscillations. We refer briefly to tune diagnostics used at RHIC and intended for the SNS, and then present experimental results. Tune-based diagnostics for halo measurement (as opposed to prevention) are considerably more difficult. We present one brief example of tune-based halo measurement

  13. Dismantling techniques

    International Nuclear Information System (INIS)

    Wiese, E.

    1998-01-01

    Most of the dismantling techniques used in a Decontamination and Dismantlement (D and D) project are taken from conventional demolition practices. Some modifications to the techniques are made to limit exposure to the workers or to lessen the spread of contamination to the work area. When working on a D and D project, it is best to keep the dismantling techniques and tools as simple as possible. The workers will be more efficient and safer using techniques that are familiar to them. Prior experience with the technique or use of mock-ups is the best way to keep workers safe and to keep the project on schedule

  14. Dismantling techniques

    Energy Technology Data Exchange (ETDEWEB)

    Wiese, E.

    1998-03-13

    Most of the dismantling techniques used in a Decontamination and Dismantlement (D and D) project are taken from conventional demolition practices. Some modifications to the techniques are made to limit exposure to the workers or to lessen the spread of contamination to the work area. When working on a D and D project, it is best to keep the dismantling techniques and tools as simple as possible. The workers will be more efficient and safer using techniques that are familiar to them. Prior experience with the technique or use of mock-ups is the best way to keep workers safe and to keep the project on schedule.

  15. Contrast media in gall bladder diagnostics

    International Nuclear Information System (INIS)

    Schindler, G.; Frommhold, W.

    1982-01-01

    The justification of conventional X-ray diagnostic of bile ducts is repeatedly questioned by newer examination techniques like sonography and ERC. The indication for oral cholesgraphy is derived from its high-specifity of its statements for gall bladder diagnostic, that is as high as with sonography and does not depend on the experience of the investigator. The importance of the the void exposure is undoubted with correspondence of medicamentary litholysis for calcite identification. Furthermore, Choleocystic kineticals like Ceruletid let recognize better hyper plastic choleocysts like adenomyomatoses. The intravenous choleocyst-cholangiography posesses a clearly limited indication scheme even after introduction of sonography and ERC. The infusion method yields a better compatibility of the contrast medium with a simultaneous increased representation quality of the bile duct, that can be increased by a consequent application of the layer exposure technique. (orig.) [de

  16. Rationale diagnostic approach to biliary tract imaging

    International Nuclear Information System (INIS)

    Helmberger, H.; Huppertz, A.; Ruell, T.; Zillinger, C.; Ehrenberg, C.; Roesch, T.

    1998-01-01

    Since the introduction of MR cholangiography (MRC) diagnostic imaging of the biliary tract has been significantly improved. While percutaneous ultrasonography is still the primary examination, computed tomography (CT), conventional magnetic resonance imaging (MRI), as well as the direct imaging modalities of the biliary tract - iv cholangiography, endoscopic-retrograde-cholangiography (ERC), and percutaneous-transhepatic-cholangiography (PTC) are in use. This article discusses the clinical value of the different diagnostic techniques for the various biliary pathologies with special attention to recent developments in MRC techniques. An algorithm is presented offering a rational approach to biliary disorders. With further technical improvement shifts from ERC(P) to MRC(P) for biliary imaging could be envisioned, ERCP further concentrating on its role as a minimal invasive treatment option. (orig.) [de

  17. Nano structures for Medical Diagnostics Md

    International Nuclear Information System (INIS)

    Bellah, M.; Iqbal, S.M.; Bellah, M.; Iqbal, S.M.; Christensen, S.M.; Iqbal, S.M.; Iqbal, S.M.

    2012-01-01

    Nano technology is the art of manipulating materials on atomic or molecular scales especially to build nano scale structures and devices. The field is expanding quickly, and a lot of work is ongoing in the design, characterization, synthesis, and application of materials, structures, devices, and systems by controlling shape and size at nanometer scale. In the last few years, much work has been focused on the use of nano structures toward problems of biology and medicine. In this paper, we focus on the application of various nano structures and nano devices in clinical diagnostics and detection of important biological molecules. The discussion starts by introducing some basic techniques of micro-/nano scale fabrication that have enabled reproducible production of nano structures. The prospects, benefits, and limitations of using these novel techniques in the fields of bio detection and medical diagnostics are then discussed. Finally, the challenges of mass production and acceptance of nano technology by the medical community are considered.

  18. Spectroscopy and optical diagnostics for gases

    CERN Document Server

    Hanson, Ronald K; Goldenstein, Christopher S

    2016-01-01

    This text provides an introduction to the science that governs the interaction of light and matter (in the gas phase). It provides readers with the basic knowledge to exploit the light-matter interaction to develop quantitative tools for gas analysis (i.e. optical diagnostics) and understand and interpret the results of spectroscopic measurements. The authors pair the basics of gas‐phase spectroscopy with coverage of key optical diagnostic techniques utilized by practicing engineers and scientists to measure fundamental flow‐field properties. The text is organized to cover three sub‐topics of gas‐phase spectroscopy: (1) spectral line positions, (2) spectral line strengths, and (3) spectral lineshapes by way of absorption, emission, and scattering interactions. The latter part of the book describes optical measurement techniques and equipment. Key subspecialties include laser induced fluorescence, tunable laser absorption spectroscopy, and wavelength modulation spectroscopy. It is ideal for students an...

  19. Diagnostics of atmospheric pressure air plasmas

    International Nuclear Information System (INIS)

    Laux, C.O.; Kruger, C.H.; Zare, R.N.

    2001-01-01

    Atmospheric pressure air plasmas are often thought to be in Local Thermodynamics Equilibrium (LTE) owing to fast interspecies collisional exchanges at high pressure. As will be seen here, this assumption cannot be relied upon, particularly with respect to optical diagnostics. Large velocity gradients in flowing plasmas and/or elevated electron temperatures created by electrical discharges can result in large departures from chemical and thermal equilibrium. Diagnostic techniques based on optical emission spectroscopy (OES) and Cavity Ring-Down Spectroscopy (CRDS) have been developed and applied at Stanford University to the investigation of atmospheric pressure plasmas under conditions ranging from thermal and chemical equilibrium to thermochemical nonequilibrium. This article presents a review of selected temperature and species concentration measurement techniques useful for the study of air and nitrogen plasmas

  20. Technical diagnostics - equipment monitoring for increasing safety and availability of nuclear power plants

    International Nuclear Information System (INIS)

    Sturm, A.; Foerster, R.

    1977-01-01

    Utilization of technical diagnostics in equipment monitoring of nuclear power plants for ensuring nuclear safety, economic availability, and for decision making on necessary maintenance is reviewed. Technical diagnostics is subdivided into inspection and early detection of malfunctions. Moreover, combination of technical diagnostics and equipment monitoring, integration of technical diagnostics into maintenance strategy, and problems of introducing early detection of malfunctions into maintenance management of nuclear power plants are also discussed. In addition, a compilation of measuring techniques used in technical diagnostics has been made. The international state of the art of equipment monitoring in PWR nuclear power plants is illustrated by description of the sound and vibration measuring techniques. (author)

  1. Multimodality imaging techniques.

    Science.gov (United States)

    Martí-Bonmatí, Luis; Sopena, Ramón; Bartumeus, Paula; Sopena, Pablo

    2010-01-01

    In multimodality imaging, the need to combine morphofunctional information can be approached by either acquiring images at different times (asynchronous), and fused them through digital image manipulation techniques or simultaneously acquiring images (synchronous) and merging them automatically. The asynchronous post-processing solution presents various constraints, mainly conditioned by the different positioning of the patient in the two scans acquired at different times in separated machines. The best solution to achieve consistency in time and space is obtained by the synchronous image acquisition. There are many multimodal technologies in molecular imaging. In this review we will focus on those multimodality image techniques more commonly used in the field of diagnostic imaging (SPECT-CT, PET-CT) and new developments (as PET-MR). The technological innovations and development of new tracers and smart probes are the main key points that will condition multimodality image and diagnostic imaging professionals' future. Although SPECT-CT and PET-CT are standard in most clinical scenarios, MR imaging has some advantages, providing excellent soft-tissue contrast and multidimensional functional, structural and morphological information. The next frontier is to develop efficient detectors and electronics systems capable of detecting two modality signals at the same time. Not only PET-MR but also MR-US or optic-PET will be introduced in clinical scenarios. Even more, MR diffusion-weighted, pharmacokinetic imaging, spectroscopy or functional BOLD imaging will merge with PET tracers to further increase molecular imaging as a relevant medical discipline. Multimodality imaging techniques will play a leading role in relevant clinical applications. The development of new diagnostic imaging research areas, mainly in the field of oncology, cardiology and neuropsychiatry, will impact the way medicine is performed today. Both clinical and experimental multimodality studies, in

  2. The evaluation and impact of diagnostic tests

    International Nuclear Information System (INIS)

    Royal, H.D.; McNeil, B.J.

    1989-01-01

    The authors describe the usefulness of the techniques that are applied to study the role of tests and point out their limitations. In many instances, complex tasks must be oversimplified in order to use currently available analytic tools. Certain tools, such as decision analysis, are useful not only because they can provide insight regarding the most favorable diagnostic/therapeutic strategies but also because they can identify areas where present knowledge is inadequate and thereby help put priorities on areas of research

  3. Diagnostics of laser ablated plasma plumes

    DEFF Research Database (Denmark)

    Amoruso, S.; Toftmann, B.; Schou, Jørgen

    2004-01-01

    The effect of an ambient gas on the expansion dynamics of laser ablated plasmas has been studied for two systems by exploiting different diagnostic techniques. First, the dynamics of a MgB2 laser produced plasma plume in an Ar atmosphere has been investigated by space-and time-resolved optical...... of the laser ablated plasma plume propagation in a background gas. (C) 2003 Elsevier B.V All rights reserved....

  4. Diagnostic methods of fatty liver disease

    International Nuclear Information System (INIS)

    Kukuk, Guido Matthias; Sprinkart, Alois Martin; Traeber, Frank

    2017-01-01

    Fatty liver disease is defined as an abnormal accumulation of lipids into the cytoplasm of hepatocytes. Different kinds of fatty liver diseases are becoming the most important etiologies of end-stage liver disease in the western world. Because fatty liver is a theoretically reversible process, timely and accurate diagnosis is a prerequisite for potential therapeutic options. This work describes major diagnostic methods and discusses particular advantages and disadvantages of various techniques.

  5. Diagnostic imaging of craniopharyngioma; Diagnostyka obrazowa czaszkogardlakow

    Energy Technology Data Exchange (ETDEWEB)

    Gradzki, J.; Nowak, S.; Paprzycki, W. [Akademia Medyczna, Poznan (Poland)

    1993-12-31

    40 patients have been examined with operational and histological confirmation of craniopharyngioma. CT image and X-ray plane of skull were performed in case all of these patients. TMR was conformed to examine 4 patients. X-ray planes was compared to CT. CT permits tumor cyst detection. The efficacy of mentioned above diagnostic techniques was compared with surgical findings. (author). 7 refs, 5 figs, 2 tabs.

  6. DIAGNOSTICS AND REGENERATION OF COMMON RAIL INJECTORS

    Directory of Open Access Journals (Sweden)

    Łukasz KONIECZNY

    2015-03-01

    Full Text Available The article presents the methodology of Common Rail injector diagnostic, regeneration and regulation with use of professional test stands. The EPS 815 machine can be used to test and repair all BOSCH injectors fully satisfying the producer requirements and standards. The article describes an example injector diagnosis with use of such test stand and additionally presents appropriate injector regeneration and encoding techniques

  7. Vírus da leucemia felina: análise da classificação da infecção, das técnicas de diagnóstico e da eficácia da vacinação com o emprego de técnicas sensíveis de detecção viral Feline leukemia virus: infection outcomes, diagnostic techniques and vaccine efficacy analysis employing sensitive techniques of virus detection

    Directory of Open Access Journals (Sweden)

    Andreza Soriano Figueiredo

    2011-11-01

    was also demonstrated the detection of proviral DNA and RNA in cats believed to be immune to infection after vaccination. Therefore, the objectives of this review were to demonstrate the implications of the use of sensitive techniques for viral detection in the interpretation and classification of FeLV infection and reconsider the techniques for FeLV diagnostic purposes. In addition, it was presented the results concerning the effectiveness of FeLV vaccination with the use of these techniques.

  8. Beyond Diagnostic Accuracy: The Clinical Utility of Diagnostic Tests

    NARCIS (Netherlands)

    Bossuyt, Patrick M. M.; Reitsma, Johannes B.; Linnet, Kristian; Moons, Karel G. M.

    2012-01-01

    Like any other medical technology or intervention, diagnostic tests should be thoroughly evaluated before their introduction into daily practice. Increasingly, decision makers, physicians, and other users of diagnostic tests request more than simple measures of a test's analytical or technical

  9. Longitudinal Diagnostics for Short Electron Beam Bunches

    Energy Technology Data Exchange (ETDEWEB)

    Loos, H.; /SLAC

    2010-06-11

    Single-pass free electron lasers require high peak currents from ultra-short electron bunches to reach saturation and an accurate measurement of bunch length and longitudinal bunch profile is necessary to control the bunch compression process from low to high beam energy. The various state-of-the-art diagnostics methods from ps to fs time scales using coherent radiation detection, RF deflection, and other techniques are presented. The use of linear accelerators as drivers for free electron lasers (FEL) and the advent of single-pass (SASE) FELs has driven the development of a wide range of diagnostic techniques for measuring the length and longitudinal distribution of short and ultra-short electron bunches. For SASE FELs the radiation power and the length of the undulator needed to achieve saturation depend strongly on the charge density of the electron beam. In the case of X-ray FELs, this requires the accelerator to produce ultra-high brightness beams with micron size transverse normalized emittances and peak currents of several kA through several stages of magnetic bunch compression. Different longitudinal diagnostics are employed to measure the peak current and bunch profile along these stages. The measurement techniques can be distinguished into different classes. Coherent methods detect the light emitted from the beam by some coherent radiation process (spectroscopic measurement), or directly measure the Coulomb field traveling with the beam (electro-optic). Phase space manipulation techniques map the time coordinate onto a transverse dimension and then use conventional transverse beam diagnostics (transverse deflector, rf zero-phasing). Further methods measure the profile or duration of an incoherent light pulse emitted by the bunch at wavelengths much shorted than the bunch length (streak camera, fluctuation technique) or modulate the electron beam at an optical wavelength and then generate a narrow bandwidth radiation pulse with the longitudinal profile of

  10. Computer tomography as a diagnostic technique in psychiatry

    Energy Technology Data Exchange (ETDEWEB)

    Strobl, G.; Reisner, T.; Zeiler, K. (Vienna Univ. (Austria). Psychiatrische Klinik; Vienna Univ. (Austria). Neurologische Klinik)

    1980-01-01

    CT findings in 516 hospitalized psychiatric patients are presented. The patients were classified in 9 groups according to a modified ICD classification, and type and incidence of pathological findings - almost exclusively degenerative processes of the brain - were registered. Diffuse cerebral atrophies are most frequent in the groups alcoholism and alcohol psychoses (44.0%) and psychoses and mental disturbances accompanying physical diseases . In schizophrenics, (almost exclusively residual and defect states) and in patients with affective psychosis diffuse cerebral atrophies are much less frequent (11.3% and 9.2%) than stated in earlier publications. Neurosis, changes in personality, or abnormal behaviour are hardly ever accompanied by cerebral atrophy. Problems encountered in the attempt to establish objective criteria for a diagnosis of cerebral atrophy on the basis of CT pictures are discussed. The computed tomograph does not permit conclusions on the etiology of diffuse atrophic processes.

  11. Contribution a l'amelioration des techniques de diagnostic des ...

    African Journals Online (AJOL)

    Recurring fever is manifested by high fever with headache, vomiting, fatigue and feeling cold. These symptoms make recurring fever be confused either with malaria or with fever of unknown etiology. The purpose of this work is to make available to research laboratories in endemic areas of malaria and relapsing fever ...

  12. Computer tomography as a diagnostic technique in psychiatry

    International Nuclear Information System (INIS)

    Strobl, G.; Reisner, T.; Zeiler, K.; Vienna Univ.

    1980-01-01

    CT findings in 516 hospitalized psychiatric patients are presented. The patients were classified in 9 groups according to a modified ICD classification, and type and incidence of pathological findings - almost exclusively degenerative processes of the brain - were registered. Diffuse cerebral atrophies are most frequent in the groups alcoholism and alcohol psychoses (44.0%) and psychoses and mental disturbances accompanying physical diseases. In schizophrenics, (almost exclusively residual and defect states) and in patients with affective psychosis diffuse cerebral atrophies are much less frequent (11.3% and 9.2%) than stated in earlier publications. Neurosis, changes in personality, or abnormal behaviour are hardly ever accompanied by cerebral atrophy. Problems encountered in the attempt to establish objective criteria for a diagnosis of cerebral atrophy on the basis of CT pictures are discussed. The computed tomograph does not permit conclusions on the etiology of diffuse atrophic processes. (orig.) [de

  13. Radiation protection of patients in X-ray diagnostic techniques

    International Nuclear Information System (INIS)

    Gerhardt, P.

    1975-01-01

    The author states as a result that the care taken by the physician and the technical assistant is the most important factor in reducing the radiation exposure of patients. A fair relation between efficiency and possible unnecessary exposure is provided by careful and conscientious work which has to be based on sound knowledge of the effects of ionizing radiation on the organism and of the possibilities of reducing the doses responsible for these effects. (orig./AK) [de

  14. Actinic Keratosis and Non-Invasive Diagnostic Techniques: An Update

    Science.gov (United States)

    Casari, Alice; Chester, Johanna; Pellacani, Giovanni

    2018-01-01

    Actinic keratosis represents the earliest manifestation of non-melanoma skin cancer. Because of their risk of progression to invasive squamous cell carcinoma, an earlier diagnosis and treatment are mandatory. Their diagnosis sometimes could represent a challenge even for expert dermatologists. Dermoscopy, confocal laser microscopy and optical coherence tomography could help clinicians in diagnosis. PMID:29316678

  15. Reference Guide for Building Diagnostics Equipment and Techniques

    Science.gov (United States)

    1989-07-01

    imaging systems, can be cali- 6155 El Camino Real, Carlsbad, Calif. 92008, (619) brated in temperature and radiosity . 931-3617; FUR Systems Inc., 16505...of microproces- or ctigital) in degrees Celsius or Fahrenheit or a sor technology, state-of-the-art optical and sight- radiosity display in Btu/ft2

  16. Lithium-ion battery diagnostic and prognostic techniques

    Science.gov (United States)

    Singh, Harmohan N.

    2009-11-03

    Embodiments provide a method and a system for determining cell imbalance condition of a multi-cell battery including a plurality of cell strings. To determine a cell imbalance condition, a charge current is applied to the battery and is monitored during charging. The charging time for each cell string is determined based on the monitor of the charge current. A charge time difference of any two cell strings in the battery is used to determine the cell imbalance condition by comparing with a predetermined acceptable charge time difference for the cell strings.

  17. Neutron diagnostics on TFTR utilizing the Campbelling technique

    International Nuclear Information System (INIS)

    England, A.C.; Hendel, H.W.; Neischmidt, E.B.

    1986-01-01

    The authors report modified commercial neutron counting equipment installed on a tokamak fusion test reactor (TFTR) which utilizes the Campbelling theorem to monitor the neutron source strength at very high neutron count rates. Campbelling utilizes the large amplitude fluctuation from neutron events in the detectors to discriminate against small amplitude noise events. Source strengths yielding equivalent count rates a factor of five higher than possible in the conventional count rate mode have been obtained to date. The concept of Campbelling is discussed and the particular application to TFTR is illustrated

  18. Neutron diagnostics on TFTR utilizing the Campbelling technique

    International Nuclear Information System (INIS)

    England, A.C.; Hendel, H.W.; Nieschmidt, E.B.

    1986-01-01

    Modified commercial equipment installed on the tokamak fusion test reactor (TFTR) at Princeton Plasma Physics Laboratory (PPPL) utilizes Campbell's mean square voltage theorem to monitor the neutron source strength at neutron count rates orders of magnitude above the capability of the count rate mode. Campbelling uses the large amplitude fluctuations from neutron fission events in the detectors to discriminate against small amplitude γ ray and other noise events. Source strengths yielding equivalent count rates a factor of 5 greater than possible in the conventional count rate mode have been obtained to date. The concept of Campbelling is discussed and the particular application to TFTR is illustrated. Fundamental advantages are the extended useful range of the detectors by a factor of --10 4 and gamma rejection by a factor of --10 3 . Some results are shown and the neutron source strengths obtained are compared to those from conventional counting circuits and from other detectors whose outputs have not yet suffered counting losses

  19. Measurement Techniques for Flow Diagnostic in ITAM Impulse Wind Tunnels

    Science.gov (United States)

    2010-04-01

    whose acoustic resistance is identical to that of the piezoelement material. To attenuate the effect of vibrations of the casing 4 and model walls...mercury thermometers, resistance thermometers, thermocouples, optical pyrometers , and a number of spectroscopic methods have gained widespread...known method of optical pyrometers , which allows temperature measurements above 1600°С. As it is well known this method is based on using the laws of

  20. Ex vivo confocal microscopy: a new diagnostic technique for mucormycosis.

    Science.gov (United States)

    Leclercq, A; Cinotti, E; Labeille, B; Perrot, J L; Cambazard, F

    2016-05-01

    Skin-dedicated ex vivo confocal microscopy (EVCM) has so far mainly been employed to identify cutaneous tumours on freshly excised samples. We present two cases where EVCM has been used to diagnose cutaneous mucormycosis. The skin biopsies were evaluated by the skin-dedicated ex vivo confocal microscope VivaScope 2500(®) (MAVIG GmbH, Munich Germany) under both reflectance and fluorescence mode. Conventional direct optical examination on skin scraping and histological examination were later performed. Mucormycetes observed by EVCM presented as hyper-reflective elongated 20 μm in diameter structures with perpendicular ramifications. Fungi were found both under reflectance and fluorescence mode and were better visible with acridine orange under fluorescence EVCM. Conventional direct optical examination on skin scraping and histological examination found the same elongated and branching structures confirming the presence of Mucormycetes. Ex vivo confocal microscopy has both the advantages of being fast as the direct optical examination, and to be able to show the localisation of the fungi in the tissue like the histological examination. In our cases, EVCM allowed to rapidly confirm the clinical diagnosis of mucormycosis, which is essential for the treatment of this fungal infection. Further studies are needed to compare the performance of EVCM with the findings of conventional histological and mycological examinations. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.