Sample records for developing country immunization
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Human immunization in developing countries: practical and theoretical problems and prospects.
Arya, S C
1994-11-01
While measles, pertussis and tetanus were responsible during the early 1990s for nearly two million deaths in developing countries, no deaths were attributable to them in industrialized countries. More than 96% of global deaths by communicable diseases were also from developing countries. Respiratory infections ranked first in communicable morbidity at all ages. Even though vaccines of bacterial or viral origin or a prophylactic for passive immunization are produced in 24, 16 and 15 developing countries, respectively, none of the developing countries manufactures a plasma-derived prophylactic or biological response modifier. Nearly every country relies on import of one or more vaccines. The suboptimal performance of otherwise meritorious products has been due to faulty vaccine administration practices. Expanding populations, poverty and lack of education, cold-chain defects, and inadequate facilities for transport of vaccines to target populations in remote areas have been responsible for the poor performance of vaccines in the community. Mounting foreign debts and budgetary strains resulting from the care and prevention of AIDS/HIV have considerably strained national and international efforts to offer routine vaccinations in childhood and pregnancy. This dismal situation could be tackled through research to obtain environmentally stable products for prophylactic use and monoclonal antibody formulations for passive immunization, and through international financial and technical support. All countries should exercise some technical control of the quality of imported and indigenous vaccines during their use for curative or prophylactic purposes. The involvement of private clinicians in immunizations would strengthen national efforts for control of communicable diseases including AIDS, but this is not enough if the local factors cited above are not improved.
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Mureed, Sheh; Somronghtong, Ratana; Kumar, Ramesh; Ghaffar, Abdul; Chapman, Robert S
2015-01-01
Globally immunisation has to be considered as a most effective and efficient public health intervention to reduce morbidity and mortality among children. Most of the children from developing countries are still not fully immunized due to multiple factors including lack of interventions, awareness, and financial constraints and due to limited resource. Conversely, this review has identified the effectiveness of interventions to increase the immunisation coverage among children of developing countries. Systematic review by using PRISMA statement ("preferred reporting items for systematic reviews and meta-analyses") has been conducted in English. published articles on Pub Med, Scopus, Cochrane, Medline and ISI by searching keywords like immunizations, childhood vaccination and developing countries has been accessed. Only randomised controlled trial and quasi-experimental studies designs were included in the final analysis based on quality assessment by adopting the Down and Black checklist and finally pooled analysis was done by random effect model. This systematic review has been approved and registered by University of York. A total of 16,570 published articles were accessed and finally 10 fulfilled our criteria that were analysed and interpreted. It demonstrated that the interventions has shown significantly increase vaccine coverage for childhood cluster diseases (OR 2.136 and p 0.05) and full vaccination schedule (OR 1.342 and p>0.05). Systematic review has concluded that the professional interventions are an effective while in improving the child immunisation coverage for cluster diseases in developing countries, major effect on DTP an.d measles.
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International Nuclear Information System (INIS)
Mureed, S.; Somronghtong, R.; Kumar, R.
2015-01-01
Globally immunisation has to be considered as a most effective and efficient public health intervention to reduce morbidity and mortality among children. Most of the children from developing countries are still not fully immunized due to multiple factors including lack of interventions, awareness, and financial constraints and due to limited resource. Conversely, this review has identified the effectiveness of interventions to increase the immunisation coverage among children of developing countries. Methods: Systematic review by using PRISMA statement (preferred reporting items for systematic reviews and meta-analyses) has been conducted in English published articles on Pub Med, Scopus, Cochrane, Medline and ISI by searching keywords like immunizations, childhood vaccination and developing countries has been accessed. Only randomised controlled trial and quasi-experimental studies designs were included in the final analysis based on quality assessment by adopting the Down and Black checklist and finally pooled analysis was done by random effect model. This systematic review has been approved and registered by University of York. Results: A total of 16,570 published articles were accessed and finally 10 fulfilled our criteria that were analysed and interpreted. It demonstrated that the interventions has shown significantly increase vaccine coverage for childhood cluster diseases (OR 2.136 and p <0.05).Furthermore, it has been proved that an effect was more prominent for DTP (OR 2.397 and p<0.05) and measles (OR 2.628 and p<0.05), not as much for polio (OR 2.284 and p>0.05) and full vaccination schedule (OR 1.342 and p>0.05). Conclusions: Systematic review has concluded that the professional interventions are an effective while in improving the child immunisation coverage for cluster diseases in developing countries, major effect on DTP and measles. (author)
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Use of m-Health in polio eradication and other immunization activities in developing countries.
Kim, Sara S; Patel, Manish; Hinman, Alan
2017-03-07
Reaching the children that are chronically missed by routine immunization services has been a key pillar of success in achieving progress toward polio eradication. The rapid advancement and accessibility of mobile technology ("mHealth") in low and lower middle income countries provides an important opportunity to apply novel, innovative approaches to provide vaccine services. We sought to document the use and effectiveness of mHealth in immunization programs in low and lower middle income countries. We particularly focused on mHealth approaches used in polio eradication efforts by the Global Polio Eradication Initiative (GPEI) to leverage the knowledge and lessons learned that may be relevant for enhancing ongoing immunization services. In June 2016, the electronic database PubMed was searched for peer reviewed studies that focused on efforts to improve immunization programs (both ongoing immunization services and supplemental immunization activities or campaigns) through mobile technology in low and lower middle income countries. The search yielded 317 papers of which 25 met the inclusion criteria. One additional article was included from the hand searching process. mHealth was used for reminder and recall, monitoring and surveillance, vaccine acceptance, and campaign strategic planning. Mobile phones were the most common mobile device used. Of the 26 studies, 21 of 26 studies (80.8%) reported that mHealth improved immunization efforts. mHealth interventions can effectively enhance immunization services in low and lower middle income countries. With the growing capacity and access to mobile technology, mHealth can be a powerful and sustainable tool for enhancing the reach and impact of vaccine programs. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Country Immunization Information System Assessments - Kenya, 2015 and Ghana, 2016.
Scott, Colleen; Clarke, Kristie E N; Grevendonk, Jan; Dolan, Samantha B; Ahmed, Hussein Osman; Kamau, Peter; Ademba, Peter Aswani; Osadebe, Lynda; Bonsu, George; Opare, Joseph; Diamenu, Stanley; Amenuvegbe, Gregory; Quaye, Pamela; Osei-Sarpong, Fred; Abotsi, Francis; Ankrah, Joseph Dwomor; MacNeil, Adam
2017-11-10
The collection, analysis, and use of data to measure and improve immunization program performance are priorities for the World Health Organization (WHO), global partners, and national immunization programs (NIPs). High quality data are essential for evidence-based decision-making to support successful NIPs. Consistent recording and reporting practices, optimal access to and use of health information systems, and rigorous interpretation and use of data for decision-making are characteristics of high-quality immunization information systems. In 2015 and 2016, immunization information system assessments (IISAs) were conducted in Kenya and Ghana using a new WHO and CDC assessment methodology designed to identify root causes of immunization data quality problems and facilitate development of plans for improvement. Data quality challenges common to both countries included low confidence in facility-level target population data (Kenya = 50%, Ghana = 53%) and poor data concordance between child registers and facility tally sheets (Kenya = 0%, Ghana = 3%). In Kenya, systemic challenges included limited supportive supervision and lack of resources to access electronic reporting systems; in Ghana, challenges included a poorly defined subdistrict administrative level. Data quality improvement plans (DQIPs) based on assessment findings are being implemented in both countries. IISAs can help countries identify and address root causes of poor immunization data to provide a stronger evidence base for future investments in immunization programs.
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Poy, Alain; van den Ent, Maya M V X; Sosler, Stephen; Hinman, Alan R; Brown, Sidney; Sodha, Samir; Ehlman, Daniel C; Wallace, Aaron S; Mihigo, Richard
2017-07-01
To monitor immunization-system strengthening in the Polio Eradication Endgame Strategic Plan 2013-2018 (PEESP), the Global Polio Eradication Initiative identified 1 indicator: 10% annual improvement in third dose of diphtheria- tetanus-pertussis-containing vaccine (DTP3) coverage in polio high-risk districts of 10 polio focus countries. A multiagency team, including staff from the African Region, developed a comprehensive list of outcome and process indicators measuring various aspects of the performance of an immunization system. The development and implementation of the dashboard to assess immunization system performance allowed national program managers to monitor the key immunization indicators and stratify by high-risk and non-high-risk districts. Although only a single outcome indicator goal (at least 10% annual increase in DTP3 coverage achieved in 80% of high-risk districts) initially existed in the endgame strategy, we successfully added additional outcome indicators (eg, decreasing the number of DTP3-unvaccinated children) as well as program process indicators focusing on cold chain, stock availability, and vaccination sessions to better describe progress on the pathway to raising immunization coverage. When measuring progress toward improving immunization systems, it is helpful to use a comprehensive approach that allows for measuring multiple dimensions of the system. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.
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Funding gap for immunization across 94 low- and middle-income countries.
Ozawa, Sachiko; Grewal, Simrun; Portnoy, Allison; Sinha, Anushua; Arilotta, Richard; Stack, Meghan L; Brenzel, Logan
2016-12-07
Novel vaccine development and production has given rise to a growing number of vaccines that can prevent disease and save lives. In order to realize these health benefits, it is essential to ensure adequate immunization financing to enable equitable access to vaccines for people in all communities. This analysis estimates the full immunization program costs, projected available financing, and resulting funding gap for 94 low- and middle-income countries over five years (2016-2020). Vaccine program financing by country governments, Gavi, and other development partners was forecasted for vaccine, supply chain, and service delivery, based on an analysis of comprehensive multi-year plans together with a series of scenario and sensitivity analyses. Findings indicate that delivery of full vaccination programs across 94 countries would result in a total funding gap of $7.6 billion (95% uncertainty range: $4.6-$11.8 billion) over 2016-2020, with the bulk (98%) of the resources required for routine immunization programs. More than half (65%) of the resources to meet this funding gap are required for service delivery at $5.0 billion ($2.7-$8.4 billion) with an additional $1.1 billion ($0.9-$2.7 billion) needed for vaccines and $1.5 billion ($1.1-$2.0 billion) for supply chain. When viewed as a percentage of total projected costs, the funding gap represents 66% of projected supply chain costs, 30% of service delivery costs, and 9% of vaccine costs. On average, this funding gap corresponds to 0.2% of general government expenditures and 2.3% of government health expenditures. These results suggest greater need for country and donor resource mobilization and funding allocation for immunizations. Both service delivery and supply chain are important areas for further resource mobilization. Further research on the impact of advances in service delivery technology and reductions in vaccine prices beyond this decade would be important for efficient investment decisions for
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Microneedle patches for vaccination in developing countries.
Arya, Jaya; Prausnitz, Mark R
2016-10-28
Millions of people die of infectious diseases each year, mostly in developing countries, which could largely be prevented by the use of vaccines. While immunization rates have risen since the introduction of the Expanded Program on Immunization (EPI), there remain major challenges to more effective vaccination in developing countries. As a possible solution, microneedle patches containing an array of micron-sized needles on an adhesive backing have been developed to be used for vaccine delivery to the skin. These microneedle patches can be easily and painlessly applied by pressing against the skin and, in some designs, do not leave behind sharps waste. The patches are single-dose, do not require reconstitution, are easy to administer, have reduced size to simplify storage, transportation and waste disposal, and offer the possibility of improved vaccine immunogenicity, dose sparing and thermostability. This review summarizes vaccination challenges in developing countries and discusses advantages that microneedle patches offer for vaccination to address these challenges. We conclude that microneedle patches offer a powerful new technology that can enable more effective vaccination in developing countries. Copyright © 2015. Published by Elsevier B.V.
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What's in a country average? Wealth, gender, and regional inequalities in immunization in India.
Pande, Rohini P; Yazbeck, Abdo S
2003-12-01
Recent attention to Millennium Development Goals by the international development community has led to the formation of targets to measure country-level achievements, including achievements on health status indicators such as childhood immunization. Using the example of immunization in India, this paper demonstrates the importance of disaggregating national averages for a better understanding of social disparities in health. Specifically, the paper uses data from the India National Family Health Survey 1992-93 to analyze socioeconomic, gender, urban-rural and regional inequalities in immunization in India for each of the 17 largest states. Results show that, on average, southern states have better immunization levels and lower immunization inequalities than many northern states. Wealth and regional inequalities are correlated with overall levels of immunization in a non-linear fashion. Gender inequalities persist in most states, including in the south, and seem unrelated to overall immunization or the levels of other inequalities measured here. This suggests that the gender differentials reflect deep-seated societal factors rather than health system issues per se. The disaggregated information and analysis used in this paper allows for setting more meaningful targets than country averages. Additionally, it helps policy makers and planners to understand programmatic constraints and needs by identifying disparities between sub-groups of the population, including strong and weak performers at the state and regional levels.
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Levin, Ann; Kaddar, Miloud
2011-07-01
The authors conducted a literature review on the role of the private sector in low- and middle-income countries. The review indicated that relatively few studies have researched the role of the private sector in immunization service delivery in these countries. The studies suggest that the private sector is playing different roles and functions according to economic development levels, the governance structure and the general presence of the private sector in the health sector. In some countries, generally low-income countries, the private for-profit sector is contributing to immunization service delivery and helping to improve access to traditional EPI vaccines. In other countries, particularly middle-income countries, the private for-profit sector often acts to facilitate early adoption of new vaccines and technologies before introduction and generalization by the public sector. The not-for-profit sector plays an important role in extending access to traditional EPI vaccines, particularly in low-income countries. Not-for-profit facilities are situated in rural as well as urban areas and are more likely to be coordinated with public services than the private for-profit sector. Although numerous studies on non-governmental organizations (NGOs) suggest that the extent of NGO provision of immunization services in low- and middle-income countries is substantial, the contribution of this sector is poorly documented, leading to a lack of recognition of its role at national and global levels. Studies on quality of immunization service provision at private health facilities suggest that it is sometimes inadequate and needs to be monitored. Although some articles on public-private collaboration exist, little was found on the extent to which governments are effectively interacting with and regulating the private sector. The review revealed many geographical and thematic gaps in the literature on the role and regulation of the private sector in the delivery of immunization
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Developed-developing country partnerships: Benefits to developed countries?
Directory of Open Access Journals (Sweden)
Syed Shamsuzzoha B
2012-06-01
Full Text Available Abstract Developing countries can generate effective solutions for today’s global health challenges. This paper reviews relevant literature to construct the case for international cooperation, and in particular, developed-developing country partnerships. Standard database and web-based searches were conducted for publications in English between 1990 and 2010. Studies containing full or partial data relating to international cooperation between developed and developing countries were retained for further analysis. Of 227 articles retained through initial screening, 65 were included in the final analysis. The results were two-fold: some articles pointed to intangible benefits accrued by developed country partners, but the majority of information pointed to developing country innovations that can potentially inform health systems in developed countries. This information spanned all six WHO health system components. Ten key health areas where developed countries have the most to learn from the developing world were identified and include, rural health service delivery; skills substitution; decentralisation of management; creative problem-solving; education in communicable disease control; innovation in mobile phone use; low technology simulation training; local product manufacture; health financing; and social entrepreneurship. While there are no guarantees that innovations from developing country experiences can effectively transfer to developed countries, combined developed-developing country learning processes can potentially generate effective solutions for global health systems. However, the global pool of knowledge in this area is virgin and further work needs to be undertaken to advance understanding of health innovation diffusion. Even more urgently, a standardized method for reporting partnership benefits is needed—this is perhaps the single most immediate need in planning for, and realizing, the full potential of international
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Developed-developing country partnerships: benefits to developed countries?
Syed, Shamsuzzoha B; Dadwal, Viva; Rutter, Paul; Storr, Julie; Hightower, Joyce D; Gooden, Rachel; Carlet, Jean; Bagheri Nejad, Sepideh; Kelley, Edward T; Donaldson, Liam; Pittet, Didier
2012-06-18
Developing countries can generate effective solutions for today's global health challenges. This paper reviews relevant literature to construct the case for international cooperation, and in particular, developed-developing country partnerships. Standard database and web-based searches were conducted for publications in English between 1990 and 2010. Studies containing full or partial data relating to international cooperation between developed and developing countries were retained for further analysis. Of 227 articles retained through initial screening, 65 were included in the final analysis. The results were two-fold: some articles pointed to intangible benefits accrued by developed country partners, but the majority of information pointed to developing country innovations that can potentially inform health systems in developed countries. This information spanned all six WHO health system components. Ten key health areas where developed countries have the most to learn from the developing world were identified and include, rural health service delivery; skills substitution; decentralisation of management; creative problem-solving; education in communicable disease control; innovation in mobile phone use; low technology simulation training; local product manufacture; health financing; and social entrepreneurship. While there are no guarantees that innovations from developing country experiences can effectively transfer to developed countries, combined developed-developing country learning processes can potentially generate effective solutions for global health systems. However, the global pool of knowledge in this area is virgin and further work needs to be undertaken to advance understanding of health innovation diffusion. Even more urgently, a standardized method for reporting partnership benefits is needed--this is perhaps the single most immediate need in planning for, and realizing, the full potential of international cooperation between developed and
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Nader, Alice Abou; de Quadros, Ciro; Politi, Claudio; McQuestion, Michael
2015-04-01
Financing is becoming increasingly important as the cost of immunizing the world's children continues to rise. By 2015, that cost will likely exceed US$60 per infant as new vaccines are introduced into national immunization programs. In 2006, 51 lower and lower middle income countries reported spending a mean US$12 per surviving infant on routine immunization. By 2012, the figure had risen to $20, a 67% increase. This study tests the hypothesis that lower and lower middle income countries will spend more on their routine immunization programs as their economies grow. A panel data regression approach is used. Expenditures reported by governments annually (2006-12) through the World Health Organization/UNICEF Joint Reporting Form are regressed on lagged annual per capita gross national income (GNI), controlling for prevailing mortality levels, immunization program performance, corruption control efforts, geographical region and correct reporting. Results show the expenditures increased with GNI. Expressed as an elasticity, the countries spent approximately $6.32 on immunization for every $100 in GNI increase from 2006 to 2012. Projecting forward and assuming continued annual GNI growth rates of 10.65%, countries could be spending $60 per infant by 2020 if national investment functions increase 4-fold. Given the political will, this result implies countries could fully finance their routine immunization programs without cutting funding for other programs. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine © The Author 2014; all rights reserved.
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Menzies, Nicolas A; Suharlim, Christian; Geng, Fangli; Ward, Zachary J; Brenzel, Logan; Resch, Stephen C
2017-10-06
Evidence on immunization costs is a critical input for cost-effectiveness analysis and budgeting, and can describe variation in site-level efficiency. The Expanded Program on Immunization Costing and Financing (EPIC) Project represents the largest investigation of immunization delivery costs, collecting empirical data on routine infant immunization in Benin, Ghana, Honduras, Moldova, Uganda, and Zambia. We developed a pooled dataset from individual EPIC country studies (316 sites). We regressed log total costs against explanatory variables describing service volume, quality, access, other site characteristics, and income level. We used Bayesian hierarchical regression models to combine data from different countries and account for the multi-stage sample design. We calculated output elasticity as the percentage increase in outputs (service volume) for a 1% increase in inputs (total costs), averaged across the sample in each country, and reported first differences to describe the impact of other predictors. We estimated average and total cost curves for each country as a function of service volume. Across countries, average costs per dose ranged from $2.75 to $13.63. Average costs per child receiving diphtheria, tetanus, and pertussis ranged from $27 to $139. Within countries costs per dose varied widely-on average, sites in the highest quintile were 440% more expensive than those in the lowest quintile. In each country, higher service volume was strongly associated with lower average costs. A doubling of service volume was associated with a 19% (95% interval, 4.0-32) reduction in costs per dose delivered, (range 13% to 32% across countries), and the largest 20% of sites in each country realized costs per dose that were on average 61% lower than those for the smallest 20% of sites, controlling for other factors. Other factors associated with higher costs included hospital status, provision of outreach services, share of effort to management, level of staff training
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Maximizing protection from use of oral cholera vaccines in developing country settings
Desai, Sachin N; Cravioto, Alejandro; Sur, Dipika; Kanungo, Suman
2014-01-01
When oral vaccines are administered to children in lower- and middle-income countries, they do not induce the same immune responses as they do in developed countries. Although not completely understood, reasons for this finding include maternal antibody interference, mucosal pathology secondary to infection, malnutrition, enteropathy, and previous exposure to the organism (or related organisms). Young children experience a high burden of cholera infection, which can lead to severe acute dehydrating diarrhea and substantial mortality and morbidity. Oral cholera vaccines show variations in their duration of protection and efficacy between children and adults. Evaluating innate and memory immune response is necessary to understand V. cholerae immunity and to improve current cholera vaccine candidates, especially in young children. Further research on the benefits of supplementary interventions and delivery schedules may also improve immunization strategies. PMID:24861554
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Nohynek, H; Wichmann, O; D Ancona, F
2013-12-01
During the twenty-first century, the development of national immunization programmes (NIP) has matured into robust processes where evidence-based methodologies and frameworks have increasingly been adopted. A key role in the decision-making and recommending processes is played by National Immunization Technical Advisory Groups (NITAGs). In a survey performed among European Union member states, Norway and Iceland, in February 2013, 85% of the 27 responding countries reported having established a NITAG, and of these, 45% have formal frameworks in place for the systematic development of vaccination recommendations. Independent of whether a formal framework is in place, common key factors are addressed by all NITAGs and also in countries without NITAGs. The four main factors addressed by all were: disease burden in the country, severity of the disease, vaccine effectiveness or efficacy, and vaccine safety at population level. Mathematical modelling and cost-effectiveness analyses are still not common tools. Differences in the relative weighting of these key factors, differences in data or assumptions on country-specific key factors, and differences in existing vaccination systems and financing, are likely to be reasons for differences in NITAG recommendations, and eventually NIPs, across Europe. Even if harmonization of NIPs is presently not a reasonable aim, systematic reviews and the development of mathematical/economic models could be performed at supranational level, thus sharing resources and easing the present work-load of NITAGs. Nevertheless, it has been argued that harmonization would ease central purchase of vaccines, thus reducing the price and increasing access to new vaccines. © 2013 The Authors Clinical Microbiology and Infection © 2013 European Society of Clinical Microbiology and Infectious Diseases.
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Ashish Singh
2015-01-01
Using households with a pair of male-female siblings from DHS surveys, this paper estimates gender based within-household inequality in immunization status of children (aged 1-5 years) from Bangladesh, India, Nepal and Pakistan. I find substantial level of gender based within-household inequality in immunization status (with large inter-country variations) in the countries studied. Further, I estimate household fixed-effects models for immunization status and find significant difference betwe...
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Malnutrition and vaccination in developing countries
Prendergast, Andrew J.
2015-01-01
Malnutrition contributes to an estimated 45% of deaths among children under 5 years of age in developing countries, predominantly due to infections. Malnourished children therefore stand to benefit hugely from vaccination, but malnutrition has been described as the most common immunodeficiency globally, suggesting that they may not be able to respond effectively to vaccines. The immunology of malnutrition remains poorly characterized, but is associated with impairments in mucosal barrier integrity, and innate and adaptive immune dysfunction. Despite this, the majority of malnourished children can mount a protective immune response following vaccination, although the timing, quality and duration of responses may be impaired. This paper reviews the evidence for vaccine immunogenicity in malnourished children, discusses the importance of vaccination in prevention of malnutrition and highlights evidence gaps in our current knowledge. PMID:25964453
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Mallya, Apoorva; Sandhu, Hardeep; Anya, Blanche-Philomene; Yusuf, Nasir; Ntakibirora, Marcelline; Hasman, Andreas; Fahmy, Kamal; Agbor, John; Corkum, Melissa; Sumaili, Kyandindi; Siddique, Anisur Rahman; Bammeke, Jane; Braka, Fiona; Andriamihantanirina, Rija; Ziao, Antoine-Marie C.; Djumo, Clement; Yapi, Moise Desire; Sosler, Stephen; Eggers, Rudolf
2017-01-01
Abstract Nine polio areas of expertise were applied to broader immunization and mother, newborn and child health goals in ten focus countries of the Polio Eradication Endgame Strategic Plan: policy & strategy development, planning, management and oversight (accountability framework), implementation & service delivery, monitoring, communications & community engagement, disease surveillance & data analysis, technical quality & capacity building, and partnerships. Although coverage improvements depend on multiple factors and increased coverage cannot be attributed to the use of polio assets alone, 6 out of the 10 focus countries improved coverage in three doses of diphtheria tetanus pertussis containing vaccine between 2013 and 2015. Government leadership, evidence-based programming, country-driven comprehensive operational annual plans, community partnership and strong accountability systems are critical for all programs and polio eradication has illustrated these can be leveraged to increase immunization coverage and equity and enhance global health security in the focus countries. PMID:28838187
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AIDS in the developing countries.
Tinker, J
1988-01-01
Without a medical miracle, it seems inevitable that the Acquired Immune Deficiency Syndrome (AIDS) pandemic will become not only the most serious public health problem of this generation but a dominating issue in 3rd world development. As a present-day killer, AIDS in developing countries is insignificant compared to malaria, tuberculosis, or infant diarrhea, but this number is misleading in 3 ways. First, it fails to reflect the per capita rate of AIDS cases. On this basis, Bermuda, French Guyana, and the Bahamas have much higher rates than the US. Second, there is extensive underreporting of AIDS cases in most developing nations. Finally, the number of AIDS cases indicates where the epidemic was 5-7 years ago, when these people became infected. Any such projections of the growth of 3rd world AIDS epidemics are at this time based on epidemiologic data from the industrialized rations of the north and on the assumption that the virus acts similarly in the south as it does in the US and Europe. Yet, 3rd world conditions differ. Sexually transmitted diseases usually are more prevalent, and people have a different burden of other diseases and of other stresses to the immune system. In Africa, AIDS already is heavily affecting the mainstream population in some nations. Some regions will approach net population declines over the next decade. How far their populations eventually could decline because of AIDS is unclear and will depend crucially on countermeasures taken or not taken over the next 1-2 years. In purely economic terms, AIDS will affect the direct costs of health care, expenses which are unrealistic for most 3rd world countries. Further, the vast majority of deaths from AIDS in developing countries will occur among those in the sexually active age groups -- the wage earners and food producers. Deaths in this age group also will reduce the labor available for farming and industry. AIDS epidemics also may have significant effects on foreign investment in the 3rd
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van den Ent, Maya M V X; Mallya, Apoorva; Sandhu, Hardeep; Anya, Blanche-Philomene; Yusuf, Nasir; Ntakibirora, Marcelline; Hasman, Andreas; Fahmy, Kamal; Agbor, John; Corkum, Melissa; Sumaili, Kyandindi; Siddique, Anisur Rahman; Bammeke, Jane; Braka, Fiona; Andriamihantanirina, Rija; Ziao, Antoine-Marie C; Djumo, Clement; Yapi, Moise Desire; Sosler, Stephen; Eggers, Rudolf
2017-07-01
Nine polio areas of expertise were applied to broader immunization and mother, newborn and child health goals in ten focus countries of the Polio Eradication Endgame Strategic Plan: policy & strategy development, planning, management and oversight (accountability framework), implementation & service delivery, monitoring, communications & community engagement, disease surveillance & data analysis, technical quality & capacity building, and partnerships. Although coverage improvements depend on multiple factors and increased coverage cannot be attributed to the use of polio assets alone, 6 out of the 10 focus countries improved coverage in three doses of diphtheria tetanus pertussis containing vaccine between 2013 and 2015. Government leadership, evidence-based programming, country-driven comprehensive operational annual plans, community partnership and strong accountability systems are critical for all programs and polio eradication has illustrated these can be leveraged to increase immunization coverage and equity and enhance global health security in the focus countries. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.
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Early determinants of chronic disease in developing countries.
Crowther, Nigel J
2012-10-01
The prevalence of non-communicable diseases (NCDs) is rising in developing countries. The extent to which this is due to a nutritional mismatch in foetal and adult life is unknown however, studies in such countries show that the risk of chronic diseases is increased in low birthweight subjects who become obese adults. Immune dysfunction is also linked to low birthweight. Therefore, in countries where communicable diseases are prevalent, infection may be exacerbated by factors acting in utero. It is also possible that the foetal growth-retarding effects of maternal Human Immunodeficiency Virus (HIV) and malaria infection may contribute to an increased risk of NCDs later in life. Low birthweight and postnatal growth faltering followed by rapid weight gain define subjects who develop NCDs. Dietary interventions at specific time points in the life course may therefore be important for reducing disease risk. Copyright © 2012 Elsevier Ltd. All rights reserved.
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Childhood immunization, vaccine hesitancy, and provaccination policy in high-income countries
DEFF Research Database (Denmark)
Thomsen, Frej Klem
2017-01-01
Increasing vaccine hesitancy among parents in high-income countries and the resulting drop in early childhood immunization constitute an important public health problem, and raise the issue of what policies might be taken to promote higher rates of vaccination. This article first outlines the bac...
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The impact of access to immunization information on vaccine acceptance in three countries.
Directory of Open Access Journals (Sweden)
Lori K Handy
Full Text Available Vaccine acceptance is a critical component of sustainable immunization programs, yet rates of vaccine hesitancy are rising. Increased access to misinformation through media and anti-vaccine advocacy is an important contributor to hesitancy in the United States and other high-income nations with robust immunization programs. Little is known about the content and effect of information sources on attitudes toward vaccination in settings with rapidly changing or unstable immunization programs.The objective of this study was to explore knowledge and attitudes regarding vaccines and vaccine-preventable diseases among caregivers and immunization providers in Botswana, the Dominican Republic, and Greece and examine how access to information impacts reported vaccine acceptance.We conducted 37 focus groups and 14 semi-structured interviews with 96 providers and 153 caregivers in Botswana, the Dominican Republic, and Greece. Focus groups were conducted in Setswana, English, Spanish, or Greek; digitally recorded; and transcribed. Transcripts were translated into English, coded in qualitative data analysis software (NVivo 10, QSR International, Melbourne, Australia, and analyzed for common themes.Dominant themes in all three countries included identification of health care providers or medical literature as the primary source of vaccine information, yet participants reported insufficient communication about vaccines was available. Comments about level of trust in the health care system and government contrasted between sites, with the highest level of trust reported in Botswana but lower levels of trust in Greece.In Botswana, the Dominican Republic, and Greece, participants expressed reliance on health care providers for information and demonstrated a need for more communication about vaccines. Trust in the government and health care system influenced vaccine acceptance differently in each country, demonstrating the need for country-specific data that focus
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Hospital waste management in developing countries: A mini review.
Ali, Mustafa; Wang, Wenping; Chaudhry, Nawaz; Geng, Yong
2017-06-01
Health care activities can generate different kinds of hazardous wastes. Mismanagement of these wastes can result in environmental and occupational health risks. Developing countries are resource-constrained when it comes to safe management of hospital wastes. This study summarizes the main issues faced in hospital waste management in developing countries. A review of the existing literature suggests that regulations and legislations focusing on hospital waste management are recent accomplishments in many of these countries. Implementation of these rules varies from one hospital to another. Moreover, wide variations exist in waste generation rates within as well as across these countries. This is mainly attributable to a lack of an agreement on the definitions and the methodology among the researchers to measure such wastes. Furthermore, hospitals in these countries suffer from poor waste segregation, collection, storage, transportation and disposal practices, which can lead to occupational and environmental risks. Knowledge and awareness regarding proper waste management remain low in the absence of training for hospital staff. Moreover, hospital sanitary workers, and scavengers, operate without the provision of safety equipment or immunization. Unsegregated waste is illegally recycled, leading to further safety risks. Overall, hospital waste management in developing countries faces several challenges. Sustainable waste management practices can go a long way in reducing the harmful effects of hospital wastes.
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Options for improving effectiveness of rotavirus vaccines in developing countries.
Tissera, Marion S; Cowley, Daniel; Bogdanovic-Sakran, Nada; Hutton, Melanie L; Lyras, Dena; Kirkwood, Carl D; Buttery, Jim P
2017-04-03
Rotavirus gastroenteritis is a leading global cause of mortality and morbidity in young children due to diarrhea and dehydration. Over 85% of deaths occur in developing countries. In industrialised countries, 2 live oral rotavirus vaccines licensed in 2006 quickly demonstrated high effectiveness, dramatically reducing severe rotavirus gastroenteritis admissions in many settings by more than 90%. In contrast, the same vaccines reduced severe rotavirus gastroenteritis by only 30-60% in developing countries, but have been proven life-saving. Bridging this "efficacy gap" offers the possibility to save many more lives of children under the age of 5. The reduced efficacy of rotavirus vaccines in developing settings may be related to differences in transmission dynamics, as well as host luminal, mucosal and immune factors. This review will examine strategies currently under study to target the issue of reduced efficacy and effectiveness of oral rotavirus vaccines in developing settings.
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Amarasinghe, Ananda; Black, Steve; Bonhoeffer, Jan; Carvalho, Sandra M Deotti; Dodoo, Alexander; Eskola, Juhani; Larson, Heidi; Shin, Sunheang; Olsson, Sten; Balakrishnan, Madhava Ram; Bellah, Ahmed; Lambach, Philipp; Maure, Christine; Wood, David; Zuber, Patrick; Akanmori, Bartholomew; Bravo, Pamela; Pombo, María; Langar, Houda; Pfeifer, Dina; Guichard, Stéphane; Diorditsa, Sergey; Hossain, Md Shafiqul; Sato, Yoshikuni
2013-04-18
Serious vaccine-associated adverse events are rare. To further minimize their occurrence and to provide adequate care to those affected, careful monitoring of immunization programs and case management is required. Unfounded vaccine safety concerns have the potential of seriously derailing effective immunization activities. To address these issues, vaccine pharmacovigilance systems have been developed in many industrialized countries. As new vaccine products become available to prevent new diseases in various parts of the world, the demand for effective pharmacovigilance systems in low- and middle-income countries (LMIC) is increasing. To help establish such systems in all countries, WHO developed the Global Vaccine Safety Blueprint in 2011. This strategic plan is based on an in-depth analysis of the vaccine safety landscape that involved many stakeholders. This analysis reviewed existing systems and international vaccine safety activities and assessed the financial resources required to operate them. The Blueprint sets three main strategic goals to optimize the safety of vaccines through effective use of pharmacovigilance principles and methods: to ensure minimal vaccine safety capacity in all countries; to provide enhanced capacity for specific circumstances; and to establish a global support network to assist national authorities with capacity building and crisis management. In early 2012, the Global Vaccine Safety Initiative (GVSI) was launched to bring together and explore synergies among on-going vaccine safety activities. The Global Vaccine Action Plan has identified the Blueprint as its vaccine safety strategy. There is an enormous opportunity to raise awareness for vaccine safety in LMIC and to garner support from a large number of stakeholders for the GVSI between now and 2020. Synergies and resource mobilization opportunities presented by the Decade of Vaccines can enhance monitoring and response to vaccine safety issues, thereby leading to more equitable
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The mother-offspring dyad: microbial transmission, immune interactions and allergy development.
Jenmalm, M C
2017-12-01
The increasing prevalence of allergy in affluent countries may be caused by reduced intensity and diversity of microbial stimulation, resulting in abnormal postnatal immune maturation. Most studies investigating the underlying immunomodulatory mechanisms have focused on postnatal microbial exposure, for example demonstrating that the gut microbiota differs in composition and diversity during the first months of life in children who later do or do not develop allergic disease. However, it is also becoming increasingly evident that the maternal microbial environment during pregnancy is important in childhood immune programming, and the first microbial encounters may occur already in utero. During pregnancy, there is a close immunological interaction between the mother and her offspring, which provides important opportunities for the maternal microbial environment to influence the immune development of the child. In support of this theory, combined pre- and postnatal supplementations seem to be crucial for the preventive effect of probiotics on infant eczema. Here, the influence of microbial and immune interactions within the mother-offspring dyad on childhood allergy development will be discussed. In addition, how perinatal transmission of microbes and immunomodulatory factors from mother to offspring may shape appropriate immune maturation during infancy and beyond, potentially via epigenetic mechanisms, will be examined. Deeper understanding of these interactions between the maternal and offspring microbiome and immunity is needed to identify efficacious preventive measures to combat the allergy epidemic. © 2017 The Association for the Publication of the Journal of Internal Medicine.
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Gandhi, Gian; Lydon, Patrick; Cornejo, Santiago; Brenzel, Logan; Wrobel, Sandra; Chang, Hugh
2013-04-18
The Decade of Vaccines Global Vaccine Action Plan has outlined a set of ambitious goals to broaden the impact and reach of immunization across the globe. A projections exercise has been undertaken to assess the costs, financing availability, and additional resource requirements to achieve these goals through the delivery of vaccines against 19 diseases across 94 low- and middle-income countries for the period 2011-2020. The exercise draws upon data from existing published and unpublished global forecasts, country immunization plans, and costing studies. A combination of an ingredients-based approach and use of approximations based on past spending has been used to generate vaccine and non-vaccine delivery costs for routine programs, as well as supplementary immunization activities (SIAs). Financing projections focused primarily on support from governments and the GAVI Alliance. Cost and financing projections are presented in constant 2010 US dollars (US$). Cumulative total costs for the decade are projected to be US$57.5 billion, with 85% for routine programs and the remaining 15% for SIAs. Delivery costs account for 54% of total cumulative costs, and vaccine costs make up the remainder. A conservative estimate of total financing for immunization programs is projected to be $34.3 billion over the decade, with country governments financing 65%. These projections imply a cumulative funding gap of $23.2 billion. About 57% of the total resources required to close the funding gap are needed just to maintain existing programs and scale up other currently available vaccines (i.e., before adding in the additional costs of vaccines still in development). Efforts to mobilize additional resources, manage program costs, and establish mutual accountability between countries and development partners will all be necessary to ensure the goals of the Decade of Vaccines are achieved. Establishing or building on existing mechanisms to more comprehensively track resources and
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Directory of Open Access Journals (Sweden)
María Clara Restrepo-Méndez
2016-05-01
Full Text Available Background: An estimated 23 million infants are still not being benefitted from routine immunization services. We assessed how many children failed to be fully immunized even though they or their mothers were in contact with health services to receive other interventions. Design: Fourteen countries with Demographic and Health Surveys and Multiple Indicator Cluster Surveys carried out after 2000 and with coverage for DPT (Diphtheria-tetanus-pertussis vaccine below 70% were selected. We defined full immunization coverage (FIC as having received one dose of BCG (bacille Calmette-Guérin, one dose of measles, three doses of polio, and three doses of DPT vaccines. We tabulated FIC against: antenatal care (ANC, skilled birth attendance (SBA, postnatal care for the mother (PNC, vitamin A supplementation (VitA for the child, and sleeping under an insecticide-treated bed-net (ITN. Missed opportunities were defined as the percentage of children who failed to be fully immunized among those receiving one or more other interventions. Results: Children who received other health interventions were also more likely to be fully immunized. In nearly all countries, FIC was lowest among children born to mothers who failed to attend ANC, and highest when the mother had four or more ANC visits Côte d'Ivoire presented the largest difference in FIC: 54 percentage points (pp between having four or more ANC visits and lack of ANC. SBA was also related with higher FIC. For instance, the coverage in children without SBA was 36 pp lower than for those with SBA in Nigeria. The largest absolute difference on FIC in relation to PNC was observed for Ethiopia: 31 pp between those without and with PNC. FIC was also positively related with having received VitA. The largest absolute difference was observed in DR Congo: 41 pp. The differences in FIC among whether or not children slept under ITN were much smaller than for other interventions. Haiti presented the largest absolute
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Country branding: an imperative for developing countries | Akotia ...
African Journals Online (AJOL)
Clarifying what a country brand and country branding encompasses, this paper examines the competitive advantage a country brand engenders for developing countries. Furthermore, emphasising country branding as a social construction, this paper argues that for developing countries entrenched in the poverty cycle there ...
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Population growth changes targets for immunization.
Tuljapurkar, S; John, A M
1995-01-01
The faster the rate of population growth in developing countries, the less likely it is that current protocols for immunization against measles, rubella, and mumps will eradicate these childhood diseases. Standard protocols (timing, percentage of children to be immunized) do not take into account the rapid rates of population growth in developing countries (3.0% per year on average in sub-Saharan Africa and 2.0% in the rest of Africa, in Latin America, and in Asia, excluding China). Most public health planning models in this area were created based on static infant populations. The World Health Organization advises vaccinating at least 85% of children aged 6 to 9 months, a 3-month immunization window during which maternal antibodies are low (so the vaccination takes) and herd immunity is high (the probability that a child will encounter the disease is low because most children have been immunized). In practice, the immunization window in developing countries is 1 year or more. More susceptible children are present than assumed by the models. A larger number of susceptible babies are added each year during rapid population growth. As the age range for immunization widens, a higher percentage of children must be vaccinated to eradicate disease (chart). The proportion of each birth cohort that must be immunized rises as the population growth rate increases. At zero population growth, 94% must be vaccinated; at population growth rates greater than 3%, 98% must be vaccinated.
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Lessons Learned from Protective Immune Responses to Optimize Vaccines against Cryptosporidiosis.
Lemieux, Maxime W; Sonzogni-Desautels, Karine; Ndao, Momar
2017-12-24
In developing countries, cryptosporidiosis causes moderate-to-severe diarrhea and kills thousands of infants and toddlers annually. Drinking and recreational water contaminated with Cryptosporidium spp. oocysts has led to waterborne outbreaks in developed countries. A competent immune system is necessary to clear this parasitic infection. A better understanding of the immune responses required to prevent or limit infection by this protozoan parasite is the cornerstone of development of an effective vaccine. In this light, lessons learned from previously developed vaccines against Cryptosporidium spp. are at the foundation for development of better next-generation vaccines. In this review, we summarize the immune responses elicited by naturally and experimentally-induced Cryptosporidium spp. infection and by several experimental vaccines in various animal models. Our aim is to increase awareness about the immune responses that underlie protection against cryptosporidiosis and to encourage promotion of these immune responses as a key strategy for vaccine development. Innate and mucosal immunity will be addressed as well as adaptive immunity, with an emphasis on the balance between T H 1/T H 2 immune responses. Development of more effective vaccines against cryptosporidiosis is needed to prevent Cryptosporidium spp.-related deaths in infants and toddlers in developing countries.
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Brenzel, Logan; Young, Darwin; Walker, Damian G
2015-05-07
Few detailed facility-based costing studies of routine immunization (RI) programs have been conducted in recent years, with planners, managers and donors relying on older information or data from planning tools. To fill gaps and improve quality of information, a multi-country study on costing and financing of routine immunization and new vaccines (EPIC) was conducted in Benin, Ghana, Honduras, Moldova, Uganda and Zambia. This paper provides the rationale for the launch of the EPIC study, as well as outlines methods used in a Common Approach on facility sampling, data collection, cost and financial flow estimation for both the routine program and new vaccine introduction. Costing relied on an ingredients-based approach from a government perspective. Estimating incremental economic costs of new vaccine introduction in contexts with excess capacity are highlighted. The use of more disaggregated System of Health Accounts (SHA) coding to evaluate financial flows is presented. The EPIC studies resulted in a sample of 319 primary health care facilities, with 65% of facilities in rural areas. The EPIC studies found wide variation in total and unit costs within each country, as well as between countries. Costs increased with level of scale and socio-economic status of the country. Governments are financing an increasing share of total RI financing. This study provides a wealth of high quality information on total and unit costs and financing for RI, and demonstrates the value of in-depth facility approaches. The paper discusses the lessons learned from using a standardized approach, as well as proposes further areas of methodology development. The paper discusses how results can be used for resource mobilization and allocation, improved efficiency of services at the country level, and to inform policies at the global level. Efforts at routinizing cost analysis to support sustainability efforts would be beneficial. Copyright © 2015 Elsevier Ltd. All rights reserved.
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Directory of Open Access Journals (Sweden)
Karimov Rouslan I
2011-10-01
Full Text Available Abstract Background The Global Immunization Vision and Strategy (GIVS (2006-2015 aims to reach and sustain high levels of vaccine coverage, provide immunization services to age groups beyond infancy and to those currently not reached, and to ensure that immunization activities are linked with other health interventions and contribute to the overall development of the health sector. Objective To examine mid-term progress (through 2010 of the immunization coverage goal of the GIVS for 194 countries or territories with special attention to data from 68 countries which account for more than 95% of all maternal and child deaths. Methods We present national immunization coverage estimates for the third dose of diphtheria and tetanus toxoid with pertussis (DTP3 vaccine and the first dose of measles containing vaccine (MCV during 2000, 2005 and 2010 and report the average annual relative percent change during 2000-2005 and 2005-2010. Data are taken from the WHO and UNICEF estimates of national immunization coverage, which refer to immunizations given during routine immunization services to children less than 12 months of age where immunization services are recorded. Results Globally DTP3 coverage increased from 74% during 2000 to 85% during 2010, and MCV coverage increased from 72% during 2000 to 85% during 2010. A total of 149 countries attained or were on track to achieve the 90% coverage goal for DTP3 (147 countries for MCV coverage. DTP3 coverage ≥ 90% was sustained between 2005 and 2010 by 99 countries (98 countries for MCV. Among 68 priority countries, 28 countries were identified as having made either insufficient or no progress towards reaching the GIVS goal of 90% coverage by 2015 for DTP3 or MCV. DTP3 and MCV coverage remained Conclusion Progress towards GIVS goals highlights improvements in routine immunization coverage, yet it is troubling to observe priority countries with little or no progress during the past five years. These results
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Lessons Learned from Protective Immune Responses to Optimize Vaccines against Cryptosporidiosis
Directory of Open Access Journals (Sweden)
Maxime W. Lemieux
2017-12-01
Full Text Available In developing countries, cryptosporidiosis causes moderate-to-severe diarrhea and kills thousands of infants and toddlers annually. Drinking and recreational water contaminated with Cryptosporidium spp. oocysts has led to waterborne outbreaks in developed countries. A competent immune system is necessary to clear this parasitic infection. A better understanding of the immune responses required to prevent or limit infection by this protozoan parasite is the cornerstone of development of an effective vaccine. In this light, lessons learned from previously developed vaccines against Cryptosporidium spp. are at the foundation for development of better next-generation vaccines. In this review, we summarize the immune responses elicited by naturally and experimentally-induced Cryptosporidium spp. infection and by several experimental vaccines in various animal models. Our aim is to increase awareness about the immune responses that underlie protection against cryptosporidiosis and to encourage promotion of these immune responses as a key strategy for vaccine development. Innate and mucosal immunity will be addressed as well as adaptive immunity, with an emphasis on the balance between TH1/TH2 immune responses. Development of more effective vaccines against cryptosporidiosis is needed to prevent Cryptosporidium spp.-related deaths in infants and toddlers in developing countries.
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Non-transfusion Dependent Thalassemias: A Developing Country Perspective.
Mukherjee, Somnath; Das, Rashmi R; Raghuwanshi, Babita
2015-01-01
Non-transfusion-dependent thalassemias (NTDT) encompass a group of hereditary chronic hemolytic anemia, which, as the name indicates, not require regular blood transfusion for survival. These include β-thalassemia intermedia, hemoglobin E/β-thalassemia, and Hemoglobin H disease (α- thalassemia intermedia). Individuals with structural variant of hemoglobin especially Hemoglobin S and Hemoglobin C associated with "α" or "β" thalassemia in heterozygous condition may also present with similar features of NTDT. NTDT patients are not immune to the development of transfusion unrelated complications in the long run. These hereditary chronic hemolytic anemias are still under-recognized in developing countries like India, where the disease burden might be high causing significant morbidity. The pathophysiologic hallmark that characterizes this group of disorders (ineffective erythropoiesis, hemolysis, chronic anemia) leads to a number of serious complications, similar to transfusion dependent thalassemia. So, timely diagnosis and institution of appropriate preventive/remedial measures as well as education of patient population can help decrease the morbidity to a significant extent. In the present review, focus will be on the pathophysiological mechanisms and available management options of NTDT from a developing country perspective like India.
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Ryman, Tove K; Dietz, Vance; Cairns, K Lisa
2008-06-21
Globally, immunization services have been the center of renewed interest with increased funding to improve services, acceleration of the introduction of new vaccines, and the development of a health systems approach to improve vaccine delivery. Much of the credit for the increased attention is due to the work of the GAVI Alliance and to new funding streams. If routine immunization programs are to take full advantage of the newly available resources, managers need to understand the range of proven strategies and approaches to deliver vaccines to reduce the incidence of diseases. In this paper, we present strategies that may be used at the sub-national level to improve routine immunization programs. We conducted a systematic review of studies and projects reported in the published and gray literature. Each paper that met our inclusion criteria was rated based on methodological rigor and data were systematically abstracted. Routine-immunization - specific papers with a methodological rigor rating of greater than 60% and with conclusive results were reported. Greater than 11,000 papers were identified, of which 60 met our inclusion criteria and 25 papers were reported. Papers were grouped into four strategy approaches: bringing immunizations closer to communities (n = 11), using information dissemination to increase demand for vaccination (n = 3), changing practices in fixed sites (n = 4), and using innovative management practices (n = 7). Immunization programs are at a historical crossroads in terms of developing new funding streams, introducing new vaccines, and responding to the global interest in the health systems approach to improving immunization delivery. However, to complement this, actual service delivery needs to be strengthened and program managers must be aware of proven strategies. Much was learned from the 25 papers, such as the use of non-health workers to provide numerous services at the community level. However it was startling to see how few papers
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Clean development mechanism: Perspectives from developing countries
Energy Technology Data Exchange (ETDEWEB)
Sari, Agus P.; Meyers, Stephen
1999-06-01
This paper addresses the political acceptability and workability of CDM by and in developing countries. At COP-3 in Kyoto in 1997, the general position among developing countries changed from strong rejection of joint implementation to acceptance of CDM. The outgrowth of CDM from a proposal from Brazil to establish a Clean Development Fund gave developing countries a sense of ownership of the idea. More importantly, establishing support for sustainable development as a main goal for CDM overcame the resistance of many developing countries to accept a carbon trading mechanism. The official acceptance of CDM is not a guarantee of continued acceptance, however. Many developing countries expect CDM to facilitate a substantial transfer of technology and other resources to support economic growth. There is concern that Annex I countries may shift official development assistance into CDM in order to gain carbon credits, and that development priorities could suffer as a result. Some fear that private investments could be skewed toward projects that yield carbon credits. Developing country governments are wary regarding the strong role of the private sector envisioned for CDM. Increasing the awareness and capacity of the private sector in developing countries to initiate and implement CDM projects needs to be a high priority. While private sector partnerships will be the main vehicle for resource transfer in CDM, developing country governments want to play a strong role in overseeing and guiding the process so that it best serves their development goals. Most countries feel that establishment of criteria for sustainable development should be left to individual countries. A key issue is how CDM can best support the strengthening of local capacity to sustain and replicate projects that serve both climate change mitigation and sustainable development objectives.There is support among developing countries for commencing CDM as soon as possible. Since official commencement must
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Telemedicine for Developing Countries
Combi, Carlo; Pozzani, Gabriele
2016-01-01
Summary Background Developing countries need telemedicine applications that help in many situations, when physicians are a small number with respect to the population, when specialized physicians are not available, when patients and physicians in rural villages need assistance in the delivery of health care. Moreover, the requirements of telemedicine applications for developing countries are somewhat more demanding than for developed countries. Indeed, further social, organizational, and technical aspects need to be considered for successful telemedicine applications in developing countries. Objective We consider all the major projects in telemedicine, devoted to developing countries, as described by the proper scientific literature. On the basis of such literature, we want to define a specific taxonomy that allows a proper classification and a fast overview of telemedicine projects in developing countries. Moreover, by considering both the literature and some recent direct experiences, we want to complete such overview by discussing some design issues to be taken into consideration when developing telemedicine software systems. Methods We considered and reviewed the major conferences and journals in depth, and looked for reports on the telemedicine projects. Results We provide the reader with a survey of the main projects and systems, from which we derived a taxonomy of features of telemedicine systems for developing countries. We also propose and discuss some classification criteria for design issues, based on the lessons learned in this research area. Conclusions We highlight some challenges and recommendations to be considered when designing a telemedicine system for developing countries. PMID:27803948
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Development of gas markets in developing countries and in countries in economical transition
International Nuclear Information System (INIS)
Roze, J.; Guegan, G.; Guerrini, Y.; Marzeau, J.M.
2000-01-01
The WOC 10 working committee of the CMG 2000 worldwide gas congress was devoted to the study of gas markets in developing countries and in countries in economical transition. This committee comprises three group of studies covering the following topics: natural gas in the less developed countries (environment protection, power production, institutional framework and cooperation), natural gas in countries in economical transition (situation in Eastern Europe, reforms and investments, prices and tariffs, towards the integration to the European Union), natural gas in developing countries (financing and technology transfers, down-side gas development, economical viability, technology transfers, projects financing, recommendations), inter-region development and power production (South America, Asia, role of the worldwide bank). (J.S.)
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Probiotics, antibiotics and the immune responses to vaccines.
Praharaj, Ira; John, Sushil M; Bandyopadhyay, Rini; Kang, Gagandeep
2015-06-19
Orally delivered vaccines have been shown to perform poorly in developing countries. There are marked differences in the structure and the luminal environment of the gut in developing countries resulting in changes in immune and barrier function. Recent studies using newly developed technology and analytic methods have made it increasingly clear that the intestinal microbiota activate a multitude of pathways that control innate and adaptive immunity in the gut. Several hypotheses have been proposed for the underperformance of oral vaccines in developing countries, and modulation of the intestinal microbiota is now being tested in human clinical trials. Supplementation with specific strains of probiotics has been shown to have modulatory effects on intestinal and systemic immune responses in animal models and forms the basis for human studies with vaccines. However, most studies published so far that have evaluated the immune response to vaccines in children and adults have been small and results have varied by age, antigen, type of antibody response and probiotic strain. Use of anthelminthic drugs in children has been shown to possibly increase immunogenicity following oral cholera vaccination, lending further support to the rationale for modulation of the immune response to oral vaccination through the intestinal microbiome. © 2015 The Author(s) Published by the Royal Society. All rights reserved.
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Innate immune response development in nestling tree swallows
Stambaugh, T.; Houdek, B.J.; Lombardo, M.P.; Thorpe, P.A.; Caldwell, Hahn D.
2011-01-01
We tracked the development of innate immunity in nestling Tree Swallows (Tachycineta bicolor) and compared it to that of adults using blood drawn from nestlings during days 6, 12, and 18 of the ???20-day nestling period and from adults. Innate immunity was characterized using an in vitro assay of the ability of whole blood to kill Escherichia coli. The ability of whole blood to kill E. coli increased as nestlings matured. Neither this component of innate immunity nor right wing chord length on day18 were as developed as in adults indicating that development of the innate immune system and growth both continued after fledging. Narrow sense heritability analyses suggest that females with strong immune responses produced nestlings with strong immune responses. These data suggest nestling Tree Swallows allocated sufficient energy to support rapid growth to enable fledging by day 18, but that further development of innate immunity occurred post-fledging. ?? 2011 by the Wilson Ornithological Society.
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Measuring polio immunity to plan immunization activities.
Voorman, Arend; Lyons, Hil M
2016-11-21
The Global Polio Eradication Initiative is closer than ever to achieving a polio-free world. Immunization activities must still be carried out in non-endemic countries to maintain population immunity at levels which will stop poliovirus from spreading if it is re-introduced from still-infected areas. In areas where there is no active transmission of poliovirus, programs must rely on surrogate indicators of population immunity to determine the appropriate immunization activities, typically caregiver-reported vaccination history obtained from non-polio acute flaccid paralysis patients identified through polio surveillance. We used regression models to examine the relationship between polio vaccination campaigns and caregiver-reported polio vaccination history. We find that in many countries, vaccination campaigns have a surprisingly weak impact on these commonly used indicators. We conclude that alternative criteria and data, such as routine immunization indicators from vaccination records or household surveys, should be considered for planning polio vaccination campaigns, and that validation of such surrogate indicators is necessary if they are to be used as the basis for program planning and risk assessment. We recommend that the GPEI and similar organizations consider or continue devoting additional resources to rigorously study population immunity and campaign effectiveness in at-risk countries. Copyright © 2016 The Authors. Published by Elsevier Ltd.. All rights reserved.
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Swift, Rachel D.; Anaokar, Sameer; Hegg, Lea Anne; Eggers, Rudolf; Cochi, Stephen L.
2017-01-01
Abstract Background. The Polio Eradication and Endgame Strategic Plan (PEESP) established a target that at least 50% of the time of personnel receiving funding from the Global Polio Eradication Initiative (GPEI) for polio eradication activities (hereafter, “GPEI-funded personnel”) should be dedicated to the strengthening of immunization systems. This article describes the self-reported profile of how GPEI-funded personnel allocate their time toward immunization goals and activities beyond those associated with polio, the training they have received to conduct tasks to strengthen routine immunization systems, and the type of tasks they have conducted. Methods. A survey of approximately 1000 field managers of frontline GPEI-funded personnel was conducted by Boston Consulting Group in the 10 focus countries of the PEESP during 2 phases, in 2013 and 2014, to determine time allocation among frontline staff. Country-specific reports on the training of GPEI-funded personnel were reviewed, and an analysis of the types of tasks that were reported was conducted. Results. A total of 467 managers responded to the survey. Forty-seven percent of the time (range, 23%–61%) of GPEI-funded personnel was dedicated to tasks related to strengthening immunization programs, other than polio eradication. Less time was spent on polio-associated activities in countries that had already interrupted wild poliovirus (WPV) transmission, compared with findings for WPV-endemic countries. All countries conducted periodic trainings of the GPEI-funded personnel. The types of non–polio-related tasks performed by GPEI-funded personnel varied among countries and included surveillance, microplanning, newborn registration and defaulter tracing, monitoring of routine immunization activities, and support of district immunization task teams, as well as promotion of health behaviors, such as clean-water use and good hygiene and sanitation practices. Conclusion. In all countries, GPEI-funded personnel
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van den Ent, Maya M V X; Swift, Rachel D; Anaokar, Sameer; Hegg, Lea Anne; Eggers, Rudolf; Cochi, Stephen L
2017-07-01
The Polio Eradication and Endgame Strategic Plan (PEESP) established a target that at least 50% of the time of personnel receiving funding from the Global Polio Eradication Initiative (GPEI) for polio eradication activities (hereafter, "GPEI-funded personnel") should be dedicated to the strengthening of immunization systems. This article describes the self-reported profile of how GPEI-funded personnel allocate their time toward immunization goals and activities beyond those associated with polio, the training they have received to conduct tasks to strengthen routine immunization systems, and the type of tasks they have conducted. A survey of approximately 1000 field managers of frontline GPEI-funded personnel was conducted by Boston Consulting Group in the 10 focus countries of the PEESP during 2 phases, in 2013 and 2014, to determine time allocation among frontline staff. Country-specific reports on the training of GPEI-funded personnel were reviewed, and an analysis of the types of tasks that were reported was conducted. A total of 467 managers responded to the survey. Forty-seven percent of the time (range, 23%-61%) of GPEI-funded personnel was dedicated to tasks related to strengthening immunization programs, other than polio eradication. Less time was spent on polio-associated activities in countries that had already interrupted wild poliovirus (WPV) transmission, compared with findings for WPV-endemic countries. All countries conducted periodic trainings of the GPEI-funded personnel. The types of non-polio-related tasks performed by GPEI-funded personnel varied among countries and included surveillance, microplanning, newborn registration and defaulter tracing, monitoring of routine immunization activities, and support of district immunization task teams, as well as promotion of health behaviors, such as clean-water use and good hygiene and sanitation practices. In all countries, GPEI-funded personnel perform critical tasks in the strengthening of routine
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International Nuclear Information System (INIS)
Egerton, J.R.
2005-01-01
For vaccine production, recombinant antigens must be protective. Identifying protective antigens or candidate antigens is an essential precursor to vaccine development. Even when a protective antigen has been identified, cloning of its gene does not lead directly to vaccine development. The fimbrial protein of Dichelobacter nodosus, the agent of foot-rot in ruminants, was known to be protective. Recombinant vaccines against this infection are ineffective if expressed protein subunits are not assembled as mature fimbriae. Antigenic competition between different, but closely related, recombinant antigens limited the use of multivalent vaccines based on this technology. Recombinant antigens may need adjuvants to enhance response. DNA vaccines, potentiated with genes for different cytokines, may replace the need for aggressive adjuvants, and especially where cellular immunity is essential for protection. The expression of antigens from animal pathogens in plants and the demonstration of some immunity to a disease like rinderpest after ingestion of these, suggests an alternative approach to vaccination by injection. Research on disease pathogenesis and the identification of candidate antigens is specific to the disease agent. The definition of expression systems and the formulation of a vaccine for each disease must be followed by research to establish safety and efficacy. Where vaccines are based on unique gene sequences, the intellectual property is likely to be protected by patent. Organizations, licensed to produce recombinant vaccines, expect to recover their costs and to make a profit. The consequence is that genetically-derived vaccines are expensive. The capacity of vaccines to help animal owners of poorer countries depends not only on quality and cost but also on the veterinary infrastructure where they are used. Ensuring the existence of an effective animal health infrastructure in developing countries is as great a challenge for the developed world as
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Immunity to parasitic infection
National Research Council Canada - National Science Library
Lamb, Tracey J
2012-01-01
.... Often endemic in developing countries many parasitic diseases are neglected in terms of research funding and much remains to be understood about parasites and the interactions they have with the immune system...
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Lamichhane, Aayam; Kiyono, Hiroshi; Kunisawa, Jun
2013-12-01
The gut is equipped with a unique immune system for maintaining immunological homeostasis, and its functional immune disruption can result in the development of immune diseases such as food allergy and intestinal inflammation. Accumulating evidence has demonstrated that nutritional components play an important role in the regulation of gut immune responses and also in the development of intestinal immune diseases. In this review, we focus on the immunological functions of lipids, vitamins, and nucleotides in the regulation of the intestinal immune system and as potential targets for the control of intestinal immune diseases. © 2013 Journal of Gastroenterology and Hepatology Foundation and Wiley Publishing Asia Pty Ltd.
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Energy problems in developing countries
Energy Technology Data Exchange (ETDEWEB)
Tasugi, Hirosaburo [Japan Industrial Tech. Association, Tokyo, Japan
1989-06-20
In order to rid the people's living of poverty in developing countries, first, the production of food has been planned to increase. And then, resource development and industrialization have been tried to improve with efforts. Because of such development and an increase in population, energy consumption has been increasing. Advanced countries have supported these countries in many ways, however, there is much difference in their assistance depend on various situations such as racial, religious, and political ones. Moreover, a gap between cities and farm villages has widen since infrastructure has not been fully equipped in developing countries. The electrification ratio is used as an index to show the degree of development in developing countries. It is low in the countries where development is lagging, particularly in farm villages. This gap is an urgent problem that faces developing countries. In order to cope with the actual conditions, advanced countries including Japan should be plan to reinforce their technological and economic assistance more suitable for farm villages. Furthermore, they should also improve the assistance system which includes a measure for environmental pollution control, considering the spot directly. 3 figs., 14 tabs.
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FOOD SECURITY SITUATION OF SELECTED HIGHLY DEVELOPED COUNTRIES AGAINST DEVELOPING COUNTRIES
Karolina Pawlak
2016-01-01
The aim of the paper is to present the food security situation in selected highly developed countries and to identify consumption disparities between them and developing countries. The research is based on the data from the United Nations Food and Agriculture Organization (FAO), the Statistical Office of the European Union (Eurostat), the United Nations Statistics Division, the Organisation for Economic Co-operation and Development (OECD), World Food Programme (WFP) and selected measures used...
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Hessel, L
2009-08-01
Cervical cancer and other diseases related to human papillomavirus (HPV) represent a global public health problem. Safe and effective vaccines are now available and already used in many industrialized countries. Immunization offers the best hope for protecting the population against a disease that is the second most deadly cancer in the developing world and the first most deadly in Africa. The World Health Organization currently recommends introduction of HVP vaccination in developing countries. Widespread vaccination could be beneficial in numerous domains other than primary prevention of cervical cancer. Efforts to overcome the numerous obstacles and speed up implementation of HVP vaccination programs are now underway in many areas ranging from related scientific issues such as epidemiology and clinical research to administrative concerns such as healthcare economics, vaccination guidelines, public acceptation, program funding, and universal access. Vaccine manufacturers have committed themselves to working in partnership with national and international organizations to ensure access to HPV vaccine for all countries regardless of economic level, Although numerous issues must be resolved to optimize the use of HPV vaccines and ensure synergistic integration of vaccination, screening and treatment, current initiatives and efforts should allow introduction of HPV vaccination in developing countries in a not too distant future.
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Tetanus antibody levels among adolescent girls in developing countries
Brabin, L.; Fazio-Tirrozzo, G.; Shahid, S.; Agbaje, O.; Maxwell, S.; Broadhead, R.; Briggs, N.; Brabin, B.
2000-01-01
Neonatal and maternal tetanus infections remain an important cause of death in many countries. Few studies have reported tetanus toxoid antibody levels of adolescent girls. As part of the Expanded Programme on Immunization most girls receive up to 3 injections in early childhood, and many
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Uranium exploration in developing countries
International Nuclear Information System (INIS)
Premoli, C.
1982-01-01
The advantages to the developing countries of exploiting their uranium deposits in the next two decades to aid their own economic growth are considered. It is pointed out that in spite of the little known geology of these countries less sophisticated surveying methods have turned up large uranium deposits even in developed countries. Carborne surveys with simple crystal-detectors coupled to scintillators can be effective. Intelligent exploration in developing countries can be cheap due to low labour costs and less stringent environmental restraints and the uranium found could be sold to developed countries for their nuclear power programme. (U.K.)
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FOOD SECURITY SITUATION OF SELECTED HIGHLY DEVELOPED COUNTRIES AGAINST DEVELOPING COUNTRIES
Directory of Open Access Journals (Sweden)
Karolina Pawlak
2016-06-01
Full Text Available The aim of the paper is to present the food security situation in selected highly developed countries and to identify consumption disparities between them and developing countries. The research is based on the data from the United Nations Food and Agriculture Organization (FAO, the Statistical Office of the European Union (Eurostat, the United Nations Statistics Division, the Organisation for Economic Co-operation and Development (OECD, World Food Programme (WFP and selected measures used by the Economist Intelligence Unit (EIU for the construction of the Global Food Security Index. It has been showed that to the greatest extent the problem of maintaining food security occur in developing countries which are characterised by low per capita income, while in developed countries the scale of hunger is marginal and it afflicts less than 1% of the population. On a regional scale the daily dietary energy supply is greater than the minimum dietary energy requirement in all regions of the world, but the extent to which the dietary needs are satisfied increases along with the increase in national income. In order to reduce the problem of hunger it is necessary to solve the problem of asymmetrical distribution of global income, e.g. by taking actions to accelerate the economic growth in less developed regions and increase the purchasing power of the population.
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Modelling energy systems for developing countries
International Nuclear Information System (INIS)
Urban, F.; Benders, R.M.J.; Moll, H.C.
2007-01-01
Developing countries' energy use is rapidly increasing, which affects global climate change and global and regional energy settings. Energy models are helpful for exploring the future of developing and industrialised countries. However, energy systems of developing countries differ from those of industrialised countries, which has consequences for energy modelling. New requirements need to be met by present-day energy models to adequately explore the future of developing countries' energy systems. This paper aims to assess if the main characteristics of developing countries are adequately incorporated in present-day energy models. We first discuss these main characteristics, focusing particularly on developing Asia, and then present a model comparison of 12 selected energy models to test their suitability for developing countries. We conclude that many models are biased towards industrialised countries, neglecting main characteristics of developing countries, e.g. the informal economy, supply shortages, poor performance of the power sector, structural economic change, electrification, traditional bio-fuels, urban-rural divide. To more adequately address the energy systems of developing countries, energy models have to be adjusted and new models have to be built. We therefore indicate how to improve energy models for increasing their suitability for developing countries and give advice on modelling techniques and data requirements
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Prenatal Alcohol Exposure and the Developing Immune System.
Gauthier, Theresa W
2015-01-01
Evidence from research in humans and animals suggest that ingesting alcohol during pregnancy can disrupt the fetal immune system and result in an increased risk of infections and disease in newborns that may persist throughout life. Alcohol may have indirect effects on the immune system by increasing the risk of premature birth, which itself is a risk factor for immune-related problems. Animal studies suggest that alcohol exposure directly disrupts the developing immune system. A comprehensive knowledge of the mechanisms underlying alcohol's effects on the developing immune system only will become clear once researchers establish improved methods for identifying newborns exposed to alcohol in utero.
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Business ethics in developing countries
Directory of Open Access Journals (Sweden)
G.J. Rossouw
1992-03-01
Full Text Available Underlying this paper is the conviction that it is of the utmost importance that business ethics should indeed become an integral part of business culture in all, and therefore also in developing countries. It is not to be denied that business ethics has to a much larger extent become pari of the business culture' in developed countries than in developing countries. The primary aim of this paper is to provide an explanation for the fact that business ethics is fighting an uphill battle in becoming pari of the business culture in developing countries. Secondly, a thumbnail sketch is given of the preconditions that have to be fulfilled in order to stimulate the development of a moral business culture in developing countries. In order to achieve these goals I will focus mainly on Africa, and more specifically on South Africa.
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Entrepreneurial Intentions in Developing and Developed Countries
Iakovleva, Tatiana; Kolvereid, Lars; Stephan, Ute
2011-01-01
Purpose: This study proposes to use the Theory of Planned Behaviour to predict entrepreneurial intentions among students in five developing and nine developed countries. The purpose is to investigate whether entrepreneurial intention and its antecedents differ between developing and developed countries, and to test the theory in the two groups of…
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International Nuclear Information System (INIS)
Reid, Walter V.; Goldemberg, Jose
1998-01-01
The role of developing countries in helping to solve the problem of climate change is increasingly a focus of political controversy. With levels of greenhouse gas emissions projected to exceed those of developed countries by 2020, some industrialized countries are calling on developing countries to take stronger action to meet the commitments they have made in the Framework Convention on Climate Change (FCCC). This review of recent policy changes in developing countries, however, suggests that they are already taking little appreciated steps that reduce rates of growth in carbon emissions. Indeed, since the 1992 signing of the FCCC, carbon emission savings in developing countries may be greater than those attained by industrialized countries. A major source of these gains can be attributed to energy price reforms that are likely to have led to substantial gains in production and end-use efficiency. (author)
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Drug discovery and developments in developing countries ...
African Journals Online (AJOL)
the major burden being in developing countries. Many of ... The driving force for drug discovery and development by pharmaceutical firms ... world and particularly in the third world countries ..... GFHR (2000) Global Forum for Health Research:.
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Photovoltaic marketing in developing countries
International Nuclear Information System (INIS)
Muntasser, M.A.; Bara, M.F.; Quadri, H.A.; El-Tarabelsi, R.; La-azebi, I.F.
2000-01-01
Photovoltaic (PV) insolation-harnessing is acknowledged as the most practical economic solution to meet the requirements of one hundred million people without electricity in the developing countries. Industrialised countries in particular, have been active in utilising such technologies because they can afford the current peak watt prices of US $3-15 for such systems. The market in those countries will soon be close to saturation and attention by suppliers will have to be shifted to the already established larger market in less developed countries (LDCs). PV marketing in these developing countries, i.e. ability to penetrate the potential market, is facing tremendous hurdles. This paper reviews the present status and future directions of the PV market in developing countries as well as discusses the current technical, social, financial or geopolitical barriers and constraints, which are in line with the trends in the world. The paper concludes by making a global policy package proposal, in terms of an appeal on the global community concerned with PV to propagate proposal, in terms of an appeal on the global community concerned with PV to propagate this proposal more convincingly, perhaps to emanate from an internationally recognised 'forum', like a PV conference and exhibition, with cooperation and participation of PV manufacturers, suppliers, industrialised countries, NGOs, financial institutions and developing countries. (Author)
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Nuclear energy for developing countries
International Nuclear Information System (INIS)
Kemery, L.S.
1980-01-01
This paper examines the circumstances which must prevail before a reasonable technical, administrative and sociological case can be made to justify the introduction of nuclear power technology to a developing country. The role played by the IAEA in responding to needs of developing countries is considered and problems of nuclear plant safety and materials safeguards discussed. Plans for nuclear power in several developing countries are outlined
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The AEC and developing countries
International Nuclear Information System (INIS)
Ouvrieu, J.B.
1983-01-01
A historical background shows how AEC's activities have changed and consequently, the development of the AEC's relations with developing countries. Some examples serve to illustrate the different types of AEC cooperation with developing countries [fr
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The Social Development Summit and the developing countries.
Barnabas, A P; Kulkarni, P D; Nanavatty, M C; Singh, R R
1996-01-01
This article discusses some concerns of the 1996 UN Summit on Social Development. Conference organizers identified the three key conference issues as poverty alleviation, social integration of the marginalized and disadvantaged, and expansion of productive employment. The goal of a "society for all" means dealing with the increasing differences between rich and poor countries, the survival of weaker economies in a competitive market system, wide variations in consumption patterns between countries, attainment of political stability while respecting ethnic identity, the rise in social problems among countries with a high human development index, and increasing joblessness. The Human Development Report for 1994 emphasizes human security. Social development is not the equivalent of human resource development nor a side issue of economic growth. The integration of ethnic groups poses social and political problems. There remains a question about what political system and culture would be best for social integration. Developed countries define poverty as the inability of people and government to provide resources and necessary services for people's productive activity. Poverty in developing countries is blamed on colonialism. Globally, developed countries control 71% of world trade. Sharing resources to meet basic needs throughout the world is not an operational ideal. The highest 20% of income earners receive 83% of the world income. The culture of poverty is the strategy used by the poor to survive. Welfare is not an end in itself but does enable the poor to improve their conditions. Development that focuses on productive employment is uncertain. Developed and developing countries do not share similar perceptions of human rights. There is a question as to who should set the priorities for social development. Sustainable social development is related to preservation of natural resources, control of population growth, and promotion of social security.
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VACCINES AND IMMUNIZATION: WORLD SITUATION
Directory of Open Access Journals (Sweden)
G.H. Brundtland
2007-01-01
Full Text Available The last issue of the report «vaccines and immunization: world situation» stresses considerable success in immunization at the global level since the mid 90 s — completely total eradication of poliomyelitis across the world, as well as the drastic reduction of the new measles and tetanus cases among mothers and newborns in some poor countries. The report also briefly describes the progress in the development and implementation of the new life saving vaccines, which may save millions of lives annually. The authors have explained some of the reasons, why the global community should invest in immunization, as well as the perspectives for the use of vaccines and immunization in future.Key words: vaccine, immunization, children.
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Nuclear power in developing countries
International Nuclear Information System (INIS)
Morrison, R.W.
1980-01-01
A few of the essential issues which arise when we consider nuclear power and development together in the context of energy policy are discussed. Ethical concerns must ultimately be expressed through policies and their impact on people. There are ethical issues associated with nuclear power in the developing countries which deserve our attention. Four aspects of the question of nuclear power in developing countries are considered: their energy situation; the characteristics of nuclear power which are relevant to them; whether developing countries will undertake nuclear power programmes; and finally the ethical implications of such programmes. It is concluded that what happens in developing countries will depend more on the ethical nature of major political decisions and actions than on the particular technology they use to generate their electricity. (LL)
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Directory of Open Access Journals (Sweden)
Diyah Ayu Amalia Avina
2016-12-01
Full Text Available The purpose of this research is to explore the growing trend of outward foreign direct investments (OFDIs from developing countries to developed countries. Market-seeking and strategic asset explorations are the main motivations for conducting OFDIs in developed countries. Meanwhile, cross-border greenfield investments and cross-border mergers and acquisitions are the main entry strategies used by developing countries when penetrating the developed markets. Finally, this paper reveals mixed results about the explaining ability of John Dunning’s International Development Path (IDP theory on the patterns of selected developing markets' OFDIs to developed countries. On the one hand, China’s OFDIs follow the paths in the IDP theory. On the other hand, those of India do not confirm so.
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Reinfection immunity in schistosomiasis
International Nuclear Information System (INIS)
Kamiya, Haruo
1987-01-01
Schistosomiasis is one of the most important parasitic diseases in the world, especially in endemic areas of developing countries. This situation has prompted parasitologist to attempt intensive researches on immune mechanisms, especially those of reinfection immunity associated with eliminating challenge infection. The current knowledge of reinfection immunity against Schistosoma spp. infection was therefore reviewed briefly and discussed with special reference to our data on protective immune responses induced by radiation-attenuated cercarial infection. A recently developed technique of compressed organ autoradiography (COA) has contributed to assessing parasite attrition in immune animals following challenge infection. Our study using COA has demonstrated that major attrition of schistosomula from challenge infection occurs in the skin of CBA/Ca mice vaccinated with 20 Krad gamma radiation-attenuated cercariae of S. mansoni, while in both lungs and liver of similarly vaccinated guinea pig model. Furthermore, gamma-irradiation to cercariae affected their migration potential and surface-antigen profiles. The immunizing stimuli of gamma radiation-attenuated cercariae profoundly affected the expression of responsiveness in vaccinated animals. The change in antigenic profiles and migration potential of those vaccinating population was discussed in relation to the kinetics of reinfection immunity induced in vaccinated amimal models. These works might provide a base line data to develop a practical vaccine for schistosomiasis using defined antigens. It must be emphasized that these vaccines could serve as a practical prophylactic measure for schistosomiasis in the endemic areas, even if the vaccines fail to induce sterilizing immunity. (author). 141 refs
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Height-income association in developing countries: Evidence from 14 countries.
Patel, Pankaj C; Devaraj, Srikant
2017-12-28
The purpose of this study was to assess whether the height-income association is positive in developing countries, and whether income differences between shorter and taller individuals in developing countries are explained by differences in endowment (ie, taller individuals have a higher income than shorter individuals because of characteristics such as better social skills) or due to discrimination (ie, shorter individuals have a lower income despite having comparable characteristics). Instrumental variable regression, Oaxaca-Blinder decomposition, quantile regression, and quantile decomposition analyses were applied to a sample of 45 108 respondents from 14 developing countries represented in the Research on Early Life and Aging Trends and Effects (RELATE) study. For a one-centimeter increase in country- and sex-adjusted median height, real income adjusted for purchasing power parity increased by 1.37%. The income differential between shorter and taller individuals was explained by discrimination and not by differences in endowments; however, the effect of discrimination decreased at higher values of country- and sex-adjusted height. Taller individuals in developing countries may realize higher income despite having characteristics similar to those of shorter individuals. © 2017 Wiley Periodicals, Inc.
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Hattasingh, Weerawan; Pengsaa, Krisana; Thisyakorn, Usa
2016-03-04
The 1st Workshop on National Immunization Programs and Vaccine Coverage in Association of Southeast Asian Nations (ASEAN) Countries Group (WNIPVC-ASEAN) held a meeting on April 30, 2015, Pattaya, Thailand under the auspices of the Pediatric Infectious Diseases Society and the World Health Organization (WHO). Reports on the current status and initiatives of the national immunization program (NIP) in each ASEAN countries that attended were presented. These reports along with survey data collected from ministries of health in ASEAN countries NIPs demonstrate that good progress has been made toward the goal of the Global Vaccine Action Plan (GVAP). However, some ASEAN countries have fragile health care systems that still have insufficient vaccine coverage of some basic EPI antigens. Most ASEAN countries still do not have national coverage of some new and underused vaccines, and raising funds for the expansion of NIPs is challenging. Also, there is insufficient research into disease burden of vaccine preventable diseases and surveillance. Health care workers must advocate NIPs to government policy makers and other stakeholders as well as improve research and surveillance to achieve the goals of the GVAP. Copyright © 2016. Published by Elsevier Ltd.. All rights reserved.
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Anders, Sherry; Kinney, Dennis K
2015-08-18
Extensive research implicates disturbed immune function and development in the etiology and pathology of schizophrenia. In addition to reviewing evidence for immunological factors in schizophrenia, this paper discusses how an emerging model of atypical immune function and development helps explain a wide variety of well-established - but puzzling - findings about schizophrenia. A number of theorists have presented hypotheses that early immune system programming, disrupted by pre- and perinatal adversity, often combines with abnormal brain development to produce schizophrenia. The present paper focuses on the hypothesis that disruption of early immune system development produces a latent immune vulnerability that manifests more fully after puberty, when changes in immune function and the thymus leave individuals more susceptible to infections and immune dysfunctions that contribute to schizophrenia. Complementing neurodevelopmental models, this hypothesis integrates findings on many contributing factors to schizophrenia, including prenatal adversity, genes, climate, migration, infections, and stress, among others. It helps explain, for example, why (a) schizophrenia onset is typically delayed until years after prenatal adversity, (b) individual risk factors alone often do not lead to schizophrenia, and (c) schizophrenia prevalence rates actually tend to be higher in economically advantaged countries. Here we discuss how the hypothesis explains 10 key findings, and suggests new, potentially highly cost-effective, strategies for treatment and prevention of schizophrenia. Moreover, while most human research linking immune factors to schizophrenia has been correlational, these strategies provide ethical ways to experimentally test in humans theories about immune function and schizophrenia. This article is part of a Special Issue entitled SI: Neuroimmunology in Health And Disease. Copyright © 2015 Elsevier B.V. All rights reserved.
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Alcohol fuels for developing countries
International Nuclear Information System (INIS)
Bhattacharya, Partha
1993-01-01
The importance of alcohol as an alternative fuel has been slowly established. In countries such as Brazil, they are already used in transport and other sectors of economy. Other developing countries are also trying out experiments with alcohol fuels. Chances of improving the economy of many developing nations depends to a large extent on the application of this fuel. The potential for alcohol fuels in developing countries should be considered as part of a general biomass-use strategy. The final strategies for the development of alcohol fuel will necessarily reflect the needs, values, and conditions of the individual nations, regions, and societies that develop them. (author). 5 refs
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Prenatal Alcohol Exposure and the Developing Immune System
Gauthier, Theresa W.
2015-01-01
Evidence from research in humans and animals suggest that ingesting alcohol during pregnancy can disrupt the fetal immune system and result in an increased risk of infections and disease in newborns that may persist throughout life. Alcohol may have indirect effects on the immune system by increasing the risk of premature birth, which itself is a risk factor for immune-related problems. Animal studies suggest that alcohol exposure directly disrupts the developing immune system. A comprehensiv...
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Oral health care systems in developing and developed countries
DEFF Research Database (Denmark)
Kandelman, Daniel; Arpin, Sophie; Baez, Ramon J
2012-01-01
and to provide universal access, especially in disadvantaged communities, in both developing and developed countries. Moreover, even though the most widespread illnesses are avoidable, not all population groups are well informed about or able to take advantage of the proper measures for oral health promotion....... In addition, in many countries, oral health care needs to be fully integrated into national or community health programmes. Improving oral health is a very challenging objective in developing countries, but also in developed countries, especially with the accelerated aging of the population now underway...... intervention procedures aim, at treating existing problems and restore teeth and related structure to normal function. It is unfortunate that the low priority given to oral health hinders acquisition of data and establishment of effective periodontal care programmes in developing countries but also in some...
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Do We Need Worms to Promote Immune Health?
Weinstock, Joel V
2015-10-01
Many immune-mediated diseases like inflammatory bowel disease, multiple sclerosis, type 1 diabetes, asthma, and food allergy appeared to have increased in frequency in developed countries in the latter part of the twentieth century. Reports from less developed countries suggest that the "epidemic" of immune-mediated diseases now is spreading into these regions as well. The "hygiene hypothesis" was developed to partly explain this phenomenon. It has been proposed that modern-day sanitary living has altered our exposure to organisms that provided protection from these diseases in the past. Alternations in the composition of our intestinal flora and fauna could play a role. Helminths are a group of worm-like parasitic organisms that have adapted to live in various regions of their hosts. Epidemiological and some clinical data suggest that these organisms can protect people from developing immune-mediated diseases. Animal experimentation has shown that helminths stimulate the production of regulatory cytokines, activate regulatory T cells, and induce regulatory dendritic cells and macrophages. This could be the mechanism by which they protect the host from these diseases. Early clinical studies also suggest that helminths may prove useful for treating immunological diseases. More sophisticated clinical studies are underway, testing live helminth agents as therapeutic agents. Also, a strong effort is ongoing to discover the agents produced by helminths that modulate host immune responses with an eye on developing new, highly effective immune modulatory therapeutic agent.
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Export opportunities in developing countries
International Nuclear Information System (INIS)
Sullivan, J.
1992-01-01
Developing countries will offer major opportunities to US exporters of energy and related environmental equipment in the next ten years. These opportunities arise because the markets in developing countries will be growing much faster than those in the developed countries during this period, and because these countries will not in most cases have strong domestic manufacturers to compete against. US technologies will help these countries solve their energy, environmental, and economic development problems, and help the US solve its serious trade balance problems. This market will represent over $200 billion between now and 2000. There are, however, many potential problems. These include a lack of focus and coordination among US government trade assistance organizations, a lack of interest on the part of US firms in exporting and an unwillingness to make the needed investments, barriers put up by the governments of potential foreign customers, and strong international competition. This paper describes how the United States Agency for International Development's (A.I.D.) Office of Energy and other US agencies are helping US firms resolve these problems with a comprehensive program of information, trade promotion assistance, and co-funding of feasibility studies. In addition, there are monies available to match unfair concessionary financing offered by our major competitors
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Endocrine manipulation of growth in animals: Future prospects especially in developing countries
International Nuclear Information System (INIS)
Buttery, P.J.
1989-01-01
The successful use of a number of anabolic steroid preparations in numerous countries has demonstrated that manipulation of an animal's endocrine status can lead to a substantially enhanced growth rate. Despite evidence that, used correctly, these materials present no health hazard to the consumer of treated meat, their use is not permitted in several countries. This prohibition influences the extent of world trade in meat. Modern biotechnology offers other methods of enhancing growth, e.g. the use of peptide hormones or growth factors produced by recombinant DNA technologies. Potentially, the immune response can also be exploited to increase growth and in the longer term transgenic animals may also prove a satisfactory alternative. Animals with enhanced growth potential will however require an enhanced food supply. In many parts of the world what is required is a method to lower the nutrient demands of animals during periods of feed shortage. This approach requires a substantially different philosophy and of course separate financial resources for its development. In developing countries, despite the excitement associated with new technologies, there appears to be much more to be gained, at least in the immediate future, by improving the nutrition and the health of animals. (author). 28 refs, 6 tabs
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Cesarean Section and Chronic Immune Disorders
DEFF Research Database (Denmark)
Sevelsted, Astrid; Stokholm, Jakob; Bønnelykke, Klaus
2015-01-01
OBJECTIVES: Immune diseases such as asthma, allergy, inflammatory bowel disease, and type 1 diabetes have shown a parallel increase in prevalence during recent decades in westernized countries. The rate of cesarean delivery has also increased in this period and has been associated with the develo......OBJECTIVES: Immune diseases such as asthma, allergy, inflammatory bowel disease, and type 1 diabetes have shown a parallel increase in prevalence during recent decades in westernized countries. The rate of cesarean delivery has also increased in this period and has been associated...... with the development of some of these diseases. METHODS: Mature children born by cesarean delivery were analyzed for risk of hospital contact for chronic immune diseases recorded in the Danish national registries in the 35-year period 1977-2012. Two million term children participated in the primary analysis. We...... studied childhood diseases with a suspected relation to a deviant immune-maturation and a debut at young age. The effect of cesarean delivery on childhood disease incidences were estimated by means of confounder-adjusted incidence rate ratios with 95% confidence intervals obtained in Poisson regression...
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Nuclear data applications in developing countries
International Nuclear Information System (INIS)
Mehta, M.K.; Schmidt, J.J.
1985-01-01
The peaceful applications of nuclear science and technology currently receive an increasing attention in many developing countries. More than 15 developing countries operate, construct or plan nuclear power reactors, 70 developing countries are using or planning to use nuclear techniques in medicine, agriculture, industry, and for other vital purposes. The generation, application and computer processing of nuclear data constitute important elements of the nuclear infrastructure needed for the successful implementation of nuclear science and technology. Developing countries become increasingly aware of this need, and, with the help and cooperation of the IAEA Nuclear Data Section, are steadily gaining in experience in this field. The paper illustrates this development in typical examples. (orig.)
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Agricultural support measures of advanced countries and food insecurity in developing countries
Herrmann, Michael
2006-01-01
Many developing nations, especially the least developed countries, are subjected to recurrent spells of food insecurity. In order to understand food insecurity in these countries it is necessary to consider not only immediate or trigger-causes of food crises, but also its underlying or systemic causes. This paper argues that the agricultural support measures of advanced countries may act as a systemic cause for food insecurity in developing countries. While the import of subsidized foods by d...
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Environmental policy implementation in developing countries
International Nuclear Information System (INIS)
Gamman, J.K.
1990-01-01
This study examines why national and international policies intended to protect limited natural resources in developing countries are not effectively implemented. It employs a comparative-policy implementation in three developing countries, Barbados, St. Lucia and St. Kitts, and three foreign assistance agencies, the US Agency for International Development, the Inter-American Development Bank and the Organization of American States. The decision-making process within the countries and donor agencies is closed, preventing key stakeholders from participating. In two instances, the mutually reinforcing behavior of top officials in the countries and the donor agencies led to decisions that prevented natural resources from being protected. In all three cases, strategies to implement environmental policies failed to account for four major elements: national politics, behavior in the donor agency, the culture of decision making, and economic necessity. The existing-decision making process in both developing countries and donor agencies is dysfunctional
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Business Cycles in Developing Countries
DEFF Research Database (Denmark)
Rand, John; Tarp, Finn
2002-01-01
This paper demonstrates that developing countries differ considerably from their developed counterparts when focus is on the nature and characteristics of short run macroeconomic fluctuations. Cycles are generally shorter, and the stylized facts of business cycles across countries are more diverse...... than those of the rather uniform industrialized countries. Supply-side models are generally superior in explaining changes in output, but a “one-size fits all” approach in formulating policy is inappropriate. Our results also illustrate the critical importance of understanding business regularities...
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Literacy Campaigns in Developing Countries.
Odunuga, Segun
1984-01-01
Discusses the problem of eradicating illiteracy in developing countries, where the illiteracy rate may average about 70 percent. Looks at the Arab countries, Latin America, Africa, and India and the factors that thwart attempts to increase literacy in those countries. These include religious habits and the problem of language in multilingual…
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EU CONTRIBUTION TO SUPPORT DEVELOPING COUNTRIES
Directory of Open Access Journals (Sweden)
Diana Popa
2012-06-01
Full Text Available The paper deals with the EU aid concerning to improved the economic situation from developing countries. Therefore, the aim of this research is to identify how EU states contribute to helping poor countries, members of the World Trade Organization. For the beginning, we define the EU’position before, during and after the Doha Round – a round of WTO multilateral trade negotiations. Moreover, we analyse the development dimension, focusing on countries „marginalized” until early of XXI century in terms of international trade, because this represents the idea-axis of the Doha Round. In this context, the EU – one of the leading global commercial players and a key member of the institution mentioned above – has set several objectives to achieve the basic goal of negotiations and several ways to support developing countries. To conclude, we propose to define the key points of the European aid for least developed and developing countries.
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Mwila, Katayi; Simuyandi, Michelo; Permar, Sallie R.
2016-01-01
ABSTRACT The role of maternal immunity, received by infants either transplacentally or orally from breast milk, in rotavirus vaccine (RV) performance is evaluated here. Breastfeeding withholding has no effect on vaccine responses, but higher levels of transplacental rotavirus-specific IgG antibody contribute to reduced vaccine seroconversion. The gaps in knowledge on the factors associated with low RV efficacy in low- and middle-income countries (LMIC) remain, and further research is needed to shed more light on these issues. PMID:27847365
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Directory of Open Access Journals (Sweden)
de Pinho Helen
2009-03-01
Full Text Available Abstract Background There is broad policy consensus that a shortage of doctors and nurses is a key constraint to increasing utilization of essential health services important for achieving the health Millennium Development Goals. However there is limited research on the quantitative links between health workers and service coverage rates. We examined the relationship between doctor and nurse concentrations and utilization rates of five essential health services in developing countries. Methods We performed cross-national analyses of low- and middle-income countries by means of ordinary least squares regression with coverage rates of antenatal care, attended delivery, caesarean section, measles immunization, tuberculosis case diagnosis and care for acute respiratory infection as outcomes. Doctor, nurse and aggregate health worker (sum of doctors and nurses concentrations were the main explanatory variables. Results Nurses were associated with utilization of skilled birth attendants (P = 0.02 and doctors were associated with measles immunization rates (P = 0.01 in separate adjusted analyses. Aggregate health workers were associated with the utilization of skilled birth attendants (P Conclusion A range of health system and population-level factors aside from health workers influences coverage of health services in developing countries. However, it is also plausible that health workers who are neither doctors nor nurses, such as clinical officers and community health workers, may be providing a substantial proportion of health services. The human resources for health research agenda should be expanded beyond doctors and nurses.
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Directory of Open Access Journals (Sweden)
Timothy M Kinyanjui
Full Text Available Respiratory syncytial virus (RSV is globally ubiquitous, and infection during the first six months of life is a major risk for severe disease and hospital admission; consequently RSV is the most important viral cause of respiratory morbidity and mortality in young children. Development of vaccines for young infants is complicated by the presence of maternal antibodies and immunological immaturity, but vaccines targeted at older children avoid these problems. Vaccine development for young infants has been unsuccessful, but this is not the case for older children (> 6 m. Would vaccinating older children have a significant public health impact? We developed a mathematical model to explore the benefits of a vaccine against RSV.We have used a deterministic age structured model capturing the key epidemiological characteristics of RSV and performed a statistical maximum-likelihood fit to age-specific hospitalization data from a developing country setting. To explore the effects of vaccination under different mixing assumptions, we included two versions of contact matrices: one from a social contact diary study, and the second a synthesised construction based on demographic data. Vaccination is assumed to elicit an immune response equivalent to primary infection. Our results show that immunisation of young children (5-10 m is likely to be a highly effective method of protection of infants (<6 m against hospitalisation. The majority benefit is derived from indirect protection (herd immunity. A full sensitivity and uncertainty analysis using Latin Hypercube Sampling of the parameter space shows that our results are robust to model structure and model parameters.This result suggests that vaccinating older infants and children against RSV can have a major public health benefit.
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Energy investment in developing countries
International Nuclear Information System (INIS)
Rovani, Y.
1982-01-01
The developing countries are likely to represent the fastest growing component of the global energy demand over the next two decades. The paper presents considerations based on the World Bank's approach to the energy sector in these countries. It is considered that an accelerated development of conventional indigenous sources of energy is absolutely vital if developing countries are to attain a satisfactory rate of economic growth. The cost of the energy investment, the power sector issues, the optimal use of the resources, the role of the external financing and the need of technical assistance are reviewed. One emphasizes the role of the World Bank in analyzing and preparing projects, and in mobilizing financing from other official and commercial sources
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Problems of nuclear power in developing countries
International Nuclear Information System (INIS)
Woite, G.
1978-01-01
The problems of nuclear power in developing countries are different in nature but not less severe than in industrialized countries. So far, only five developing countries with market economies (Argentina, India, Korea, Pakistan, Taiwan) have nuclear power plants in operation with a combined net output of 2.2 GWe. Nuclear projects with a total capacity of 15 GWe are under construction in these and four other developing countries in Asia and Latin America (Brazil, Iran, Mexico, Philippines). It is expected that most of the future nuclear power installed in developing countries of Asia, Africa and Latin America will be in these countries which have overcome some of the problems of nuclear power. (orig./RW) [de
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Mobilizing technology for developing countries
Energy Technology Data Exchange (ETDEWEB)
Weiss, C Jr
1979-10-01
Mr. Weiss says that the 15 years since the UN Conference on Science, Technology, and Development in Geneva have taught us that what seem at first to be technological obstacles to development frequently turn out on closer examination to have been policy failures; that introduction of technologies into developing countries must be accompanied by institutional and policy changes if the technologies are to benefit the countries. He points out that choice of alternative technology for a developing country should depend on careful overall assessment of local techno-economic, geographical, ecological, and social factors, as well as the desired balance between growth and equity. Such a technology assessment, a key element in the choice of appropriate (i.e., locally suitable) technology for particular investment projects, should be built into procedures for project preparation and appraisal in governments and development assistance agencies. Turning to technologists, Mr. Weiss says they face a double challenge: (1) to recognize potential for new efforts to harness science and technology for the benefit of the developing countries; and (2) by understanding the social, institutional, and economic framework into which an innovation is to operate, to ease its application and diffusion, and thus speed and increase its practical impact. 25 references.
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Li, Li; Ivanova, Olga; Driss, Nadia; Tiongco-Recto, Marysia; da Silva, Rajiva; Shahmahmoodi, Shohreh; Sazzad, Hossain M S; Mach, Ondrej; Kahn, Anna-Lea; Sutter, Roland W
2014-11-01
Persons with primary immune deficiency disorders (PID), especially those disorders affecting the B-cell system, are at substantially increased risk of paralytic poliomyelitis and can excrete poliovirus chronically. However, the risk of prolonged or chronic excretion is not well characterized in developing countries. We present a summary of a country study series on poliovirus excretion among PID cases. Cases with PID from participating institutions were enrolled during the first year and after obtaining informed consent were tested for polioviruses in stool samples. Those cases excreting poliovirus were followed on a monthly basis during the second year until 2 negative stool samples were obtained. A total of 562 cases were enrolled in Bangladesh, China, Iran, Philippines, Russia, Sri Lanka, and Tunisia during 2008-2013. Of these, 17 (3%) shed poliovirus, including 2 cases with immunodeficient vaccine-derived poliovirus. Poliovirus was detected in a single sample from 5/17 (29%) cases. One case excreted for more than 6 months. None of the cases developed paralysis during the study period. Chronic polioviruses excretion remains a rare event even among individuals with PID. Nevertheless, because these individuals were not paralyzed they would have been missed by current surveillance; therefore, surveillance for polioviruses among PID should be established. © The Author 2014. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.
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Energy problems of developing countries and the development co-operation
Energy Technology Data Exchange (ETDEWEB)
Mutanen, K; Sahrman, K
1984-12-15
The technology, economy and problems of energy sector in developing countries are presented as well as the possibilities of solving energy problems, with special emphasis on how to adapt Finnish energy know-how to the conditions existing in the developing countries. The population in the developing countries has grown explosively. The worst energy problem due to this growth is the shortage of firewood. The fact that wood is used for burning is one reason for the formation of deserts. Today already about one hundred million people in developing countries suffer from shortage of energy. In the following 20-30 years it will threaten already about one billion people. Poverty in the developing countries prevents the use of fossil fuels like oil. It is likely that the developing countries already in the coming decades will have to start to use new and renewable sources of energy, like these are solar and wind energy as well as hydroelectric power. The efficiency of burning fire wood should rapidly be improved. On the other hand reforestration should be increased. Also fossil fuels are needed before new sources of energy can be used. All over the world there has been interest in the energy problems of the developing countries. The World Bank and other financing bodies are increasing their financial aid for different kinds of energy projects. The Finnish development aid is primarily bilateral and concentrated in certain countries. In the 1980's the energy sector will be one of the main fields in our development aid, at the same time as the portion of our development aid from gross national income is increasing.
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Masaitis, Alexandra
2013-04-01
The successful implementation of the environmental practices in the mining industry is of a paramount importance, as it not only prevents both local and trans-border pollution but also guarantees clean and healthy environment for the people regardless of their place of habitation. It is especially important to encourage the progress of the environmental practices implementation in developing countries because such countries have resource-oriented economy based on exploitation of nonrenewable resources. Poor environmental practices in developing countries will lead to local environmental crises that could eventually spill into surrounding countries including the most economically advanced. This abstract is a summary of a two-year research project attempted (1) to determine deficiencies of the mining sector ecological practices in developing countries and (2) to suggest substitute practices from developed countries that could be adapted to the developing countries reality. The following research methods were used: 1. The method of the system analysis, where the system is an interaction of the sets of environmental practices with the global mining sector; 2. The comparative method of inquiry, where the comparison was made between environmental protection practices as implemented in the US (developed country) and the developing countries such as RF, Mongolia mining sectors; 3. Quantitative date analysis, where date was collected from "The collection of statistic data", Russian Geographic Society Annual reports, the US EPA open reports, and the USGS Reports; The following results were obtained: Identified the systemic crisis of the ecological environmental policies and practices in the mining sector in developing countries based on the exploitation of nonrenewable resources, absence of the ecological interest by the mining companies that lack mechanisms of environmental and public health protection, the lack of insurance policy, the lack of risk assistance, and in the
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Kuper, C Frieke; van Bilsen, Jolanda; Cnossen, Hilde; Houben, Geert; Garthoff, Jossie; Wolterbeek, Andre
2016-09-01
A healthy immune status is mostly determined during early life stages and many immune-related diseases may find their origin in utero and the first years of life. Therefore, immune health optimization may be most effective during early life. This review is an inventory of immune organ maturation events in relation to developmental timeframes in minipig, rat, mouse and human. It is concluded that time windows of immune organ development in rodents can be translated to human, but minipig reflects the human timeframes better; however the lack of prenatal maternal-fetal immune interaction in minipig may cause less responsiveness to prenatal intervention. It is too early to conclude which immune parameters are most appropriate, because there are not enough comparative immune parameters. Filling these gaps will increase the predictability of results observed in experimental animals, and guide future intervention studies by assessing relevant parameters in the right corresponding developmental time frames. Copyright © 2016 Elsevier Inc. All rights reserved.
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Projected uranium requirements of developing countries
International Nuclear Information System (INIS)
Anon.
1990-01-01
The objective of this paper is to examine the uranium requirements of developing countries both in aggregate and individually. Although the cumulative uranium requirements of these countries are expected to account for less than eight percent of total requirements, the fact that many of these countries are expressing renewed interest in nuclear is, in itself, encouraging. The countries analyzed in this paper are Argentina, Brazil, Egypt, India, Israel, Mexico, Pakistan, South Africa, South Korea and Taiwan. For each country, the existing and planned nuclear capacity levels have been identified and capacity factors have been projected. For countries with no previous nuclear power, the world weighted average capacity factor for the specific reactor type is utilized. Other factors influencing nuclear power demand and operations of these developing countries will be discussed, and finally, uranium requirements based on a calculated optimal tails assay of .30 will be provided
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Directory of Open Access Journals (Sweden)
Angélica Maria Serpa Guerra
2016-10-01
Full Text Available Iron (Fe deficiency has been recognized as a public health problem due to its health and economic implications. In developing countries like Colombia this deficiency still affects a large part of its population, especially children and women in gestation. Hence the importance of developing strategies such as food fortification with iron to improve the levels of consumption in the population and offset the consequences generated by the lack of this mineral, including mental and motor development, and immune system disorders. In this review, the main concepts of iron food fortification are developed, including the main factors which influence their physiological use, its importance from the nutritional point of view, the technologies used for food fortification and the latest trends in this type of products, such as biofortification and nanotechnology, all this in order to contribute to the research and development process of nutritional strategies whose central point is iron deficiency as an strategy of prevention and control.
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Eosinophilic Esophagitis in a Developing Country: Is It Different from Developed Countries?
Directory of Open Access Journals (Sweden)
Abdulrahman Al-Hussaini
2013-01-01
Full Text Available Background and Objective. Despite the extensive reporting of eosinophilic esophagitis (EoE from industrialized developed countries, reports from developing countries are rare. The aim of our study was to determine the epidemiological, clinical, and endoscopic features of EoE and response to therapy in children and adults from a developing country, Saudi Arabia. Methods. We identified patients diagnosed with EoE in our center from 2004 to 2011. EoE was defined as esophageal mucosal infiltration with a peak eosinophil count ≥15 eosinophils/high-powered field. Results. Forty-five patients were diagnosed with EoE (37 children and 8 adults; 36 males; median age 10.5 years, range from 1–37 years. Feeding difficulty, vomiting/regurgitation, and failure to thrive predominated in young children, whereas dysphagia and food impactions predominated in older children and adults. Allergy testing revealed food sensitization in 12 of 15 patients (80%; 3 responded to elemental formula, while 8 failed to respond to dietary manipulation after the allergy testing. Thirty-nine patients achieved remission by swallowed inhaled fluticasone. The majority of patients experienced a recurrence of symptoms upon the discontinuation of fluticasone. Conclusion. Our data indicate that EoE is increasingly recognized in Saudi Arabia and show many similarities to data from North America and Europe.
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Researching routine immunization-do we know what we don't know?
Clements, C John; Watkins, Margaret; de Quadros, Ciro; Biellik, Robin; Hadler, James; McFarland, Deborah; Steinglass, Robert; Luman, Elizabeth; Hennessey, Karen; Dietz, Vance
2011-11-03
The Expanded Programme on Immunization (EPI), launched in 1974, has developed and implemented a range of strategies and practices over the last three decades to ensure that children and adults receive the vaccines they need to help protect them against vaccine-preventable diseases. Many of these strategies have been implemented, resulting in immunization coverage exceeding 80% among children one year of age in many countries. Yet millions of infants remain under-immunized or unimmunized, particularly in poorer countries. In November 2009, a panel of external experts met at the United States Centers for Disease Control and Prevention (CDC) to review and identify areas of research required to strengthen routine service delivery in developing countries. Research opportunities were identified utilizing presentations emphasizing existing research, gaps in knowledge and key questions. Panel members prioritized the topics, as did other meeting participants. Several hundred research topics covering a wide range were identified by the panel members and participants. However there were relatively few topics for which there was a consensus that immediate investment in research is warranted. The panel identified 28 topics as priorities. 18 topics were identified as priorities by at least 50% of non-panel participants; of these, five were also identified as priorities by the panel. Research needs included identifying the best ways to increase coverage with existing vaccines and introduce new vaccines, integrate other services with immunizations, and finance immunization programmes. There is an enormous range of research that could be undertaken to support routine immunization. However, implementation of strategic plans, rather than additional research will have the greatest impact on raising immunization coverage and preventing disease, disability, and death from vaccine-preventable diseases. The panel emphasized the importance of tying operational research to programmatic
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Measuring Poverty and Wellbeing in Developing Countries
DEFF Research Database (Denmark)
Arndt, Channing; Tarp, Finn
2017-01-01
Detailed analyses of poverty and wellbeing in developing countries, based on large-scale, nationally representative household surveys, have been ongoing for more than three decades. The large majority of developing countries now conduct on a regular basis a variety of household surveys—income, co......Detailed analyses of poverty and wellbeing in developing countries, based on large-scale, nationally representative household surveys, have been ongoing for more than three decades. The large majority of developing countries now conduct on a regular basis a variety of household surveys......—income, consumption, health, demographics, labour force, household enterprise, and others. And the information base in developing countries with respect to poverty and wellbeing has improved dramatically. Nevertheless, appropriate measurement of poverty remains complex and controversial; this chapter lays out...... for the reader the issues and challenges. This is particularly true in developing countries where (i) the stakes with respect to poverty reduction are high; (ii) the determinants of living standards are often volatile; and (iii) related information bases, while much improved, are often characterized...
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Electronic medical records: a developing and developed country analysis
CSIR Research Space (South Africa)
Sikhondze, NC
2016-05-01
Full Text Available of Electronic Medical Records (EMR) systems in developed and developing countries. There is a direct relationship between the income of the country and the use of electronic information and communication systems as part of healthcare systems hence the division...
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Importance of rural bioenergy for developing countries
International Nuclear Information System (INIS)
Demirbas, Ayse Hilal; Demirbas, Imren
2007-01-01
Energy resources will play an important role in the world's future. Rural bioenergy is still the predominant form of energy used by people in the less developed countries, and bioenergy from biomass accounts for about 15% of the world's primary energy consumption and about 38% of the primary energy consumption in developing countries. Furthermore, bioenergy often accounts for more than 90% of the total rural energy supplies in some developing countries. Earth life in rural areas of the world has changed dramatically over time. Industrial development in developing countries, coming at a time of low cost plentiful oil supplies, has resulted in greater reliance on the source of rural bioenergy than is true in the developed countries. In developed countries, there is a growing trend towards employing modern technologies and efficient bioenergy conversion using a range of biofuels, which are becoming cost wise competitive with fossil fuels. Currently, much attention has been a major focus on renewable alternatives in the developing countries. Renewable energy can be particularly appropriate for developing countries. In rural areas, particularly in remote locations, transmission and distribution of energy generated from fossil fuels can be difficult and expensive. Producing renewable energy locally can offer a viable alternative. Renewable energy can facilitate economic and social development in communities but only if the projects are intelligently designed and carefully planned with local input and cooperation. Particularly in poor rural areas, the costs of renewable energy projects will absorb a significant part of participants' small incomes. Bio-fuels are important because they replace petroleum fuels. Biomass and biofuels can be used as a substitute for fossil fuels to generate heat, power and/or chemicals. Generally speaking, biofuels are generally considered as offering many benefits, including sustainability, reduction of greenhouse gas emissions, regional
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Gender Imbalance and Terrorism in Developing Countries.
Younas, Javed; Sandler, Todd
2017-03-01
This article investigates whether gender imbalance may be conducive to domestic terrorism in developing countries. A female-dominated society may not provide sufficient administration, law, or order to limit domestic terrorism, especially since societies in developing countries primarily turn to males for administration, policing, and paramilitary forces. Other economic considerations support female imbalance resulting in grievance-generated terrorism. Because male dominance may also be linked to terrorism, empirical tests are ultimately needed to support our prediction. Based on panel data for 128 developing countries for 1975 to 2011, we find that female gender imbalance results in more total and domestic terrorist attacks. This female gender imbalance does not affect transnational terrorism in developing countries or domestic and transnational terrorism in developed countries. Further tests show that gender imbalance affects terrorism only when bureaucratic institutions are weak. Many robustness tests support our results.
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Cancer epidemiology in developing countries
International Nuclear Information System (INIS)
Whelan, S.L.
2002-01-01
It is estimated that there were over 10 million new cancer cases in 2000, 5.4 million of them occurring in the developing countries (Parkin et al, 2001). The marked geographical variation in cancer occurrence results in differing therapeutic priorities: North America has more new cancer cases than South-Central Asia, but there are more deaths from cancer in South-Central Asia, reflecting a different pattern of cancer rather than differences in prognosis. Prediction of future trends is difficult, but the impact of population increase and ageing will be significant, with an expected 63% increase in the population of the less developed countries in 50 years. Four sites of cancer namely breast, cervix, colorectal and nasopharyngeal carcinoma are reviewed, looking at their present and possible future importance in the context of developing countries and their aetiology
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Fundamental research in developing countries
International Nuclear Information System (INIS)
Moravesik, M.J.
1964-01-01
Technical assistance is today a widespread activity. Large numbers of persons with special qualifications in the applied sciences go to the developing countries to work on specific research and development projects, as do educationists on Fulbright or other programmes - usually to teach elementary or intermediate courses. But I believe that until now it has been rare for a person primarily interested in fundamental research to go to one of these countries to help build up advanced education and pure research work. Having recently returned from such an assignment, and having found it a most stimulating and enlightening experience, I feel moved to urge strongly upon others who may be in a position to do so that they should seek similar experience themselves. The first step is to show that advanced education and fundamental research are badly needed in the under-developed countries.
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The fight against tobacco in developing countries.
Mackay, J L
1994-02-01
The battle to reduce the tobacco epidemic is not being won; the epidemic is merely being transferred from rich to poor countries. Tobacco-related mortality will rise from the present annual global toll of 3 million to over 10 million by the year 2025. Currently, most of these deaths are in developed countries but 7 out of the 10 million deaths will occur in developing countries by 2025. Developing countries cannot afford this increase, either in terms of human health or in economic costs, such as medical and health care costs, costs of lost productivity, costs of fires or costs of the misuse of land used to grow tobacco. As many of the tobacco-related illnesses, such as lung cancer or emphysema, are incurable even with expensive technology, the key to tobacco control lies in prevention. The essential elements of a national tobacco control policy are the same for all countries throughout the world--the only differences lie in fine tuning to a country's current situation. While indigenous production and consumption of tobacco remain a problem, of particular concern is the penetration of developing countries by the transnational tobacco companies, with aggressive promotional campaigns and the use of political and commercial pressures to open up markets and to promote foreign cigarettes. This includes specific targeting of women, few of whom currently smoke in developing countries. Also, tobacco advertising revenue prevents the media from reporting on the hazards of tobacco, a particularly serious problem in developing countries where awareness of the harmfulness of tobacco is low.(ABSTRACT TRUNCATED AT 250 WORDS)
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Tu, Hong-Anh T.; Rozenbaum, Mark H.; Coyte, Peter C.; Li, Shu Chuen; Woerdenbag, Herman J.; Postma, Maarten J.
2012-01-01
Introduction: Rotavirus is the most common cause of severe diarrhoea worldwide. Vietnam is situated in the region of high rotavirus infection incidence and eligible for financial support to introduce rotavirus vaccines into the Expanded Program of Immunization (EPI) from the GAVI. This study was
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Regionalized Development and Maintenance of the Intestinal Adaptive Immune Landscape
DEFF Research Database (Denmark)
Agace, William Winston; McCoy, Kathy D.
2017-01-01
The intestinal immune system has the daunting task of protecting us from pathogenic insults while limiting inflammatory responses against the resident commensal microbiota and providing tolerance to food antigens. This role is particularly impressive when one considers the vast mucosal surface...... and changing landscape that the intestinal immune system must monitor. In this review, we highlight regional differences in the development and composition of the adaptive immune landscape of the intestine and the impact of local intrinsic and environmental factors that shape this process. To conclude, we...... review the evidence for a critical window of opportunity for early-life exposures that affect immune development and alter disease susceptibility later in life....
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Nuclear medicine in developing countries
International Nuclear Information System (INIS)
Kremenchuzky, S.; Degrossi, O.J.
1991-01-01
The economic crisis through which developing countries are passing means that every field of endeavour must adapt to new realities imposed by each particular's country's situation. Public health is no exception, although it is obviously a priority field in view of the repercussions which social and economic phenomena can have on the health of a country's inhabitants. This article briefly considers ways in which nuclear medicine facilities in Argentina may be improved
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Strategy of the Development of the Country: opinions and attitudes of the country people
Somerauerová, Jana
2009-01-01
The conception of country-side and village. Demographic development of country-side places. Case study of attitude and positions of village inhabitants outspreaded to the country-side development (opinion poll).
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Gender Imbalance and Terrorism in Developing Countries
Younas, Javed
2016-01-01
This article investigates whether gender imbalance may be conducive to domestic terrorism in developing countries. A female-dominated society may not provide sufficient administration, law, or order to limit domestic terrorism, especially since societies in developing countries primarily turn to males for administration, policing, and paramilitary forces. Other economic considerations support female imbalance resulting in grievance-generated terrorism. Because male dominance may also be linked to terrorism, empirical tests are ultimately needed to support our prediction. Based on panel data for 128 developing countries for 1975 to 2011, we find that female gender imbalance results in more total and domestic terrorist attacks. This female gender imbalance does not affect transnational terrorism in developing countries or domestic and transnational terrorism in developed countries. Further tests show that gender imbalance affects terrorism only when bureaucratic institutions are weak. Many robustness tests support our results. PMID:28232755
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Strategies for Fighting Pandemic Flu in Developing Countries
Centers for Disease Control (CDC) Podcasts
Countries throughout the world are preparing for the next influenza pandemic. Developing countries face special challenges because they don't have antiviral drugs or vaccines that more developed countries have. In this podcast, CDC's Dr. Dan Jernigan discusses new and innovative approaches that may help developing countries fight pandemic flu when it emerges.
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Cyclotrons in developing countries
International Nuclear Information System (INIS)
Vera Ruiz, Hernan
2004-01-01
Cyclotron accelerators are prolific sources of charged particle for the production of radionuclides and have become an essential tool in the practice of modern nuclear medicine by providing reliable radiotracers for SPECT and PET studies. In a recent survey conducted by the IAEA in 2001, the growth in the number of cyclotron facilities installed in laboratories and hospitals in developed as well as developing countries was recorded. This trend, which started in the late 70's, continues in the present time also and all indications are that it will continue in the next five to ten years. The reasons for this growth are several: technology involved has become more user or 'hospital friendly', third party reimbursement for several clinical studies based on F-18 PET radiopharmaceuticals at least in some of the advanced countries started in 1998 and above all, the clear irrefutable and demonstrable conclusion of the positive cost/benefit outcomes of PET studies in the field of oncology to a lesser degree, thus far, for cardiology and neurology. It is however recognizable that the overall financial cost of the technology, which comprises the premises to house the facility, the cyclotron accelerator, the corresponding radiochemistry and quality control equipment and the PET cameras can be nevertheless an expensive proposition that requires careful advance planning. This fact is even more relevant when the facility is planned for installation in a developing country, which, frequently, in addition to having a lack of sufficient financial resources, do have shortage of qualified human resources to efficiently run the facility. In spite of the above, it is fact that more and more public as well as private organizations in the developing countries are setting up cyclotron/PET programmes or are seriously considering the installation of such a facility
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Macroeconomic Volatility and Welfare in Developing Countries
Loayza, Norman V.; Rancière, Romain; Servén, Luis; Ventura, Jaume
2007-01-01
Macroeconomic Volatility and Welfare in Developing Countries: An Introduction Norman V. Loayza, Romain Ranciere, Luis Serven, ` and Jaume Ventura Macroeconomic volatility, both a source and a reflection of underdevelopment, is a fundamental concern for developing countries. This article provides a brief overview of the recent literature on macroeconomic volatility in developing countries, highlighting its causes, consequences, and possible remedies. to reduce domestic policy-induced macroecon...
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Informational and Cultural Situation in Developing Countries.
Nadirova, Goulnar
Cultural development of modern countries in the East, including the Republic of Kazakhstan, is a complicated and contradictory process, where common cultural ways were shaped differently and specifically in the countries. Common historical fate has influenced this development and given these countries some common problems, but there is some…
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Child labour in developing countries
Dvořáková, Pavla
2014-01-01
Child labour in developing countries Abstract This bachelor thesis deals with the child labour and its occurence in developing countries. The main aim is to present the basic view of this problem. The term of child labour relies here on Convention on the Rights of the Child and conventions of International Labour Organization. There are several types of child labour, in which children appear most, including the worst forms of child labour. Every type includes description of activities perform...
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Handbook of nuclear medicine practice in developing countries
International Nuclear Information System (INIS)
1992-01-01
This ''Handbook of Nuclear Medicine Practices in the Developing Countries'' is meant primarily for those, who intend to install and practice nuclear medicine in a developing country. By and large, the conventional Textbooks of nuclear medicine do note cater to the special problems and needs of these countries. The Handbook is not trying to replace these textbooks, but supplement them with special information and guidance, necessary for making nuclear medicine cost-effective and useful in a hospital of a developing country. It is written mostly by those, who have made success in their careers in nuclear medicine, in one of these countries. One way to describe this Handbook will be that it represents the ways, in which, nuclear medicine is practised in the developing countries, described by those, who have a long and authentic experience of practising nuclear medicine in a developing country
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Energy in developing countries: prospects and problems
International Nuclear Information System (INIS)
Baum, V.
1977-01-01
This paper analyses requirements for primary energy and electric power in the developing countries in the light of projections of population and economic growth. It evaluates the availability of indigenous energy resources and focuses on input requirements (capital, technology, trained personnel) for accelerated energy development; it reviews possible supplies for such inputs from domestic sources, transnational corporations, multilateral institutions, and through co-operation among the developing countries themselves and between the developing and the developed countries. The paper analyses the findings of the United Nations study ''The Future of the World Economy. A Study on the Impact of the Prospective Economic Issues and Policies on the International Development Strategy'' as far as they relate to energy and the developing countries in the light of the objectives of the Declaration on the Establishment of a New International Economic Order
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The Financial and Economic Crisis and Developing Countries
Directory of Open Access Journals (Sweden)
Bruno Gurtner
2010-03-01
Full Text Available Developing countries were hit hard by the financial and economic crisis, although the impact was somewhat delayed. Every country had different challenges to master. The closer the developing countries are interconnected with the world economy, the crasser the effects. And the incipient recovery that is becoming noticeable is, for the time being, restricted to only a few countries and regions.The crisis was transmitted primarily by trade and financial flows forcing millions back into poverty. Attainment of the Millennium Development Goals is seriously jeopardised in many countries. Many developing countries did not and do not have the resources to stimulate the economy and protect their socially disadvantaged populations to the same extent as the industrialised countries. However, many countries have made considerable efforts to mitigate the effects. Developing countries have also increased their cooperation with one another and are urgently demanding a greater voice in global economic affairs.The industrialised countries are for the most part more concerned with their own problems. Their readiness to provide more extensive aid is limited. They are under pressure from the international institutions to relax their previous dominance in favour of the increasingly strong emerging countries. A shift in power and influence that was already noticeable before the financial crisis is deepening.
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Financial globalization: gain and pain for developing countries
Sergio L. Schmukler
2004-01-01
Economies around the world are becoming increasingly interconnected by the unprecedented breadth and depth of financial globalization. Developed countries tend to be most actively involved in cross-country capital movement, but in recent years developing countries have begun to participate in the process. ; This article focuses on the integration of developing countries into the international financial system. It examines recent developments and the principal agents of financial globalization...
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Regulatory pathways for vaccines for developing countries.
Milstien, Julie; Belgharbi, Lahouari
2004-01-01
Vaccines that are designed for use only in developing countries face regulatory hurdles that may restrict their use. There are two primary reasons for this: most regulatory authorities are set up to address regulation of products for use only within their jurisdictions and regulatory authorities in developing countries traditionally have been considered weak. Some options for regulatory pathways for such products have been identified: licensing in the country of manufacture, file review by the European Medicines Evaluation Agency on behalf of WHO, export to a country with a competent national regulatory authority (NRA) that could handle all regulatory functions for the developing country market, shared manufacturing and licensing in a developing country with competent manufacturing and regulatory capacity, and use of a contracted independent entity for global regulatory approval. These options have been evaluated on the basis of five criteria: assurance of all regulatory functions for the life of the product, appropriateness of epidemiological assessment, applicability to products no longer used in the domestic market of the manufacturing country, reduction of regulatory risk for the manufacturer, and existing rules and regulations for implementation. No one option satisfies all criteria. For all options, national infrastructures (including the underlying regulatory legislative framework, particularly to formulate and implement local evidence-based vaccine policy) must be developed. WHO has led work to develop this capacity with some success. The paper outlines additional areas of action required by the international community to assure development and use of vaccines needed for the developing world. PMID:15042235
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Nuclear power for developing countries
International Nuclear Information System (INIS)
Kendall, J.; Kupitz, J.; Rogner, H. H.
2000-01-01
Nuclear power is a proven technology which currently makes a large contribution to the electricity supply in a number of countries and, to a much less extent, to heat supply in some countries. Nuclear power is economically competitive with fossil fuels for base load electricity generation in many countries, and is one of the commercially proven energy supply options that could be expanded in the future to reduce environmental burdens, especially greenhouse gas emissions, from the electricity sector. Over the past five decades, nearly ten thousand reactor-years of operating experience have been accumulated with current nuclear power plants. Building upon this background of success and applying lessons learned from the experience of operating plants, new generations of nuclear power plants have been, or are being developed. Improvements incorporated into these advance designs include features that will allow operators more time to perform equipment protection and safety actions in response to equipment failures and other off normal operating conditions, and that will reduce and simplify the actions required. Great attention is also paid to making new plants simpler to operate, inspect, maintain and repair, thus increasing their overall cost efficiency and their compatibility with the infrastructure of developing countries. The paper provides a discussion of future world energy supply and demand projections, current status and prospects for nuclear power, a short summary of advanced reactor concepts and non-electrical applications of nuclear energy for developing countries, and a review of the role of the IAEA. (author)
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Chandra, Dheeraj; Kumar, Dinesh
2018-03-01
In recent years, demand to improve child immunization coverage globally, and the development of the latest vaccines and technology has made the vaccine market very complex. The rise in such complexities often gives birth to numerous issues in the vaccine supply chain, which are the primary cause of its poor performance. Figuring out the cause of the performance problem can help you decide how to address it. The goal of the present study is to identify and analyze important issues in the supply chain of basic vaccines required for child immunization in the developing countries. Twenty-five key issues as various factors of the vaccine supply chain have been presented in this paper. Fuzzy MICMAC analysis has been carried out to classify the factors based on their driving and dependence power and to develop a hierarchy based model. Further, the findings have been discussed with the field experts to identify the critical factors. Three factors: better demand forecast, communication between the supply chain members, and proper planning and scheduling have been identified as the critical factors of vaccine supply chain. These factors should be given special care to improve vaccine supply chain performance.
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Novel roles for immune molecules in neural development: Implications for neurodevelopmental disoders
Directory of Open Access Journals (Sweden)
Paula A Garay
2010-09-01
Full Text Available Although the brain has classically been considered "immune-privileged," current research suggests extensive communication between the nervous and the immune systems in both health and disease. Recent studies demonstrate that immune molecules are present at the right place and time to modulate the development and function of the healthy and diseased CNS. Indeed, immune molecules play integral roles in the CNS throughout neural development, including affecting neurogenesis, neuronal migration, axon guidance, synapse formation, activity-dependent refinement of circuits, and synaptic plasticity. Moreover, the roles of individual immune molecules in the nervous system may change over development. This review focuses on the effects of immune molecules on neuronal connections in the mammalian central nervous system—specifically the roles for MHCI and its receptors, complement, and cytokines on the function, refinement, and plasticity of cortical and hippocampal synapses and their relationship to neurodevelopmental disorders. These functions for immune molecules during neural development suggest that they could also mediate pathological responses to chronic elevations of cytokines in neurodevelopmental disorders, including autism spectrum disorders (ASD and schizophrenia.
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Natural gas in developing countries
International Nuclear Information System (INIS)
Holwerda, B.
1998-01-01
Everywhere in the world plans are being made to stimulate the natural gas industry in developing countries. High investment costs are the biggest problem almost everywhere. Even countries with a closed economy realize that they do not get far without foreign capital. Cases are presented for Africa, Pakistan, and Indonesia
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Energy needs, developing countries and ICTP
International Nuclear Information System (INIS)
Sreenivasan, K.R.
2005-01-01
The energy consumption in the near future will go up at a more rapid rate than before. About four billion people use little energy today (1.6 billion are without electricity). The energy consumption will increase partly because more of them will begin to use more energy and partly because the population will increase (to an estimated 10-12 billion in the steady state). Dependence on fossil fuels cannot continue as now. Supplies are limited, availability will become a greater vagary as sources dry up and greenhouse effects may make them less useful even sooner. Sustainable energy options will have to be a mix of fossil fuels, nuclear energy, renewable sources and others like hydrogen. Participation of developing countries and dialogue with them are essential. Developing countries cannot follow the same path to progress as industrialized countries did in the past. Greater ingenuity is needed, which calls for greater investment in science. The industrialized countries have a large responsibility because unsustainable development in the developing part of the world will adversely affect every other part. ICTP's involvement in this respect involve dedicated scientific workshops over the years (some in cooperation with IAEA) with considerable participation from Developing Countries and TRIL Fellows. ICTP has a new section on Earth System Physics (consolidating energy issues as well). Since 1977 ICTP organized 21 courses and workshops, which were attended by about 2000 participants
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Handbook of nuclear medicine practice in developing countries
Energy Technology Data Exchange (ETDEWEB)
NONE
1993-12-31
This ``Handbook of Nuclear Medicine Practices in the Developing Countries`` is meant primarily for those, who intend to install and practice nuclear medicine in a developing country. By and large, the conventional Textbooks of nuclear medicine do note cater to the special problems and needs of these countries. The Handbook is not trying to replace these textbooks, but supplement them with special information and guidance, necessary for making nuclear medicine cost-effective and useful in a hospital of a developing country. It is written mostly by those, who have made success in their careers in nuclear medicine, in one of these countries. One way to describe this Handbook will be that it represents the ways, in which, nuclear medicine is practised in the developing countries, described by those, who have a long and authentic experience of practising nuclear medicine in a developing country Figs, tabs
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Status of nuclear power in developing countries
International Nuclear Information System (INIS)
Laue, H.J.
1982-01-01
In the context of the world-wide energy situation and the key position energy plays and will play for the economic and social development of any country, the energy demand situation up to the year 2000 is analysed. As a result, the world-wide energy demand will continue to increase, however, mainly in the developing world. Nuclear power is one of the important component in the energy mix of today and in the future. Status of nuclear power application in developing countries up to the end of the century. Any further growth of the peaceful use of nuclear power in developing countries is closely linked with the following requirements: - qualified manpower, - industrial infrastructure, - energy demand and supply assessments, - high investments, - assurance of supply of nuclear fuel and fuel cycle services, - availability of small and medium power reactors. The possible role of the IAEA in developing countries and international measures to remove some of the limitations for the peaceful use of nuclear energy in developing countries are discussed. (orig.)
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Transfer of radiation technology to developing countries
Markovic, Vitomir; Ridwan, Mohammad
1993-10-01
Transfer of technology is a complex process with many facets, options and constraints. While the concept is an important step in bringing industrialization process to agricultural based countries, it is clear, however, that a country will only benefit from a new technology if it addresses a real need, and if it can be absorbed and adapted to suit the existing cultural and technological base. International Atomic Energy Agency, as UN body, has a mandate to promote nuclear applicationsand assist Member States in transfer of technology for peaceful applications. This mandate has been pursued by many different mechanisms developed in the past years: technical assistance, coordinated research programmes, scientific and technical meetings, publications, etc. In all these activities the Agency is the organizer and initiator, but main contributions come from expert services from developed countries and, increasingly, from developing countries themselves. The technical cooperation among developing coutries more and more becomes part of different programmes. In particular, regional cooperation has been demonstrated as an effective instrument for transfer of technology from developed and among developing countries. Some examples of actual programmes are given.
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What Makes MNCs Succeed in Developing countries?
DEFF Research Database (Denmark)
Hansen, Michael W.; Gwozdz, Wencke
MNCs are increasingly investing in developing countries to be part of rapid market growth, to enhance the efficiency of their value chains, and to access abundant resources and talent. The potential gains are high, however so are the risks. Some developing country subsidiaries become top performers...... regardless of location and industry. The findings of the study have important implications for the IB literature, for managers and for policy aimed at promoting FDI in developing countries....
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Poverty—A structural problem of developing countries
Wülker, Gabriele
1981-01-01
The contrast between industrialized and developing countries is often seen as one between two opposites: Rich countries—poor countries. But the poverty in the developing countries is by no means identical with the need for help as perceived in the industrialized societies. Poverty in the Third World is, as the following article shows, a structural problem.
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Traditional Medicine in Developing Countries
DEFF Research Database (Denmark)
Thorsen, Rikke Stamp
or spiritual healer and self-treatment with herbal medicine or medicinal plants. Reliance on traditional medicine varies between countries and rural and urban areas, but is reported to be as high as 80% in some developing countries. Increased realization of the continued importance of traditional medicine has......People use traditional medicine to meet their health care needs in developing countries and medical pluralism persists worldwide despite increased access to allopathic medicine. Traditional medicine includes a variety of treatment opportunities, among others, consultation with a traditional healer...... led to the formulation of policies on the integration of traditional medicine into public health care. Local level integration is already taking place as people use multiple treatments when experiencing illness. Research on local level use of traditional medicine for health care, in particular the use...
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Country characteristics and acute diarrhea in children from developing nations: a multilevel study.
Pinzón-Rondón, Ángela María; Zárate-Ardila, Carol; Hoyos-Martínez, Alfonso; Ruiz-Sternberg, Ángela María; Vélez-van-Meerbeke, Alberto
2015-08-21
Each year 2.5 billion cases of diarrheal disease are reported in children under five years, and over 1,000 die. Country characteristics could play a role on this situation. We explored associations between country characteristics and diarrheal disease in children under 5 years of age, adjusting by child, mother and household attributes in developing countries. This study included 348,706 children from 40 nations. We conducted a multilevel analysis of data from the Demographic and Health Surveys and the World Bank. The prevalence of acute diarrhea was 14 %. Country inequalities (OR = 1.335; 95 % CI 1.117-1.663) and country's low income (OR = 1.488; 95 % CI 1.024-2.163) were associated with diarrhea, and these country characteristics changed the associations of well-known determinants of diarrhea. Specifically, living in poor countries strengthens the association of poor household wealth and mother's lack of education with the disease. Other factors associated with diarrhea were female sex of the child (OR = 0.922; 95 % CI 0.900-0.944), age of the child (OR = 0.978; 95 % CI 0.978-0.979), immunization status (OR = 0.821; 95 % CI 0.799-0.843), normal birthweight (OR = 0.879; 95 % CI 0.834-0.926), maternal age (OR = 0.987; 95 % CI 0.985-0.989), lack of maternal education (OR = 1.416; 95 % CI 1.283-1.564), working status of the mother (OR = 1.136; 95 % CI 1.106-1.167), planned pregnancy (OR = 0.774; 95 % CI 0.753-0.795), a nuclear family structure (OR = 0.949; 95 % CI 0.923-0.975), and household wealth (OR = 0.948; 95 % CI 0.921-0.977). Inequalities and lack of resources at the country level in developing countries -but not health expenditure- were associated with acute diarrhea, independently of child, family and household features. The broad environment considerably modifies well-known social determinants of acute diarrhea and public health campaigns designed to target diarrhea should consider macro characteristics of the
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ROUTINE IMMUNIZATION IN INDIA: A PERSPECTIVE
Directory of Open Access Journals (Sweden)
G Taneja
2013-08-01
Full Text Available The Universal Immunization Programme is possibly the longest and one of the biggest public health intervention measures undertaken in India. To improve immunization coverage in the country various initiatives have been undertaken since the inception of the programme in 1985; key inputs being strengthening and expanding the cold chain system, establishing a network of outreach immunization sites, alternate vaccine delivery model, capacity building of health functionaries and medical officers and intensified polio control measures. Introduction of new and underutilized vaccines, drafting of the national vaccine policy, tracking of beneficiaries through the Maternal and Child Tracking system are some of the recent developments. However in spite of more than 25 years since inception the programme is still adversely impacted by challenges across key thematic areas of programme management, cold chain and vaccine management, recording and reporting and injection safety. To further strengthen and improve service delivery 2012-13 has been declared as the “Year of Intensification of Routine Immunization” with the objective of improving immunization coverage rates across poor performing districts and states so as to attain Global Immunization Vision and Strategy goals of 90% coverage at national and more than 80% coverage at district level. Key activities planned during the year include sustained advocacy at all levels, improved communication and social mobilization, robust and regular program reviews, comprehensive microplanning, strengthening cold chain and vaccine logistics system, special catch up rounds through immunization weeks, piloting the teeka express, improved surveillance systems, strengthened partnerships and operational research activities. The current review pertains to the existing scenario of Universal Immunization Program in the country with impetus on the existing challenges, progress achieved till date as a result of various
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Gastroenterology in developing countries: Issues and advances
Mandeville, Kate L; Krabshuis, Justus; Ladep, Nimzing Gwamzhi; Mulder, Chris JJ; Quigley, Eamonn MM; Khan, Shahid A
2009-01-01
Developing countries shoulder a considerable burden of gastroenterological disease. Infectious diseases in particular cause enormous morbidity and mortality. Diseases which afflict both western and developing countries are often seen in more florid forms in poorer countries. Innovative techniques continuously improve and update gastroenterological practice. However, advances in diagnosis and treatment which are commonplace in the West, have yet to reach many developing countries. Clinical guidelines, based on these advances and collated in resource-rich environments, lose their relevance outside these settings. In this two-part review, we first highlight the global burden of gastroenterological disease in three major areas: diarrhoeal diseases, hepatitis B, and Helicobacter pylori. Recent progress in their management is explored, with consideration of future solutions. The second part of the review focuses on the delivery of clinical services in developing countries. Inadequate numbers of healthcare workers hamper efforts to combat gastroenterological disease. Reasons for this shortage are examined, along with possibilities for increased specialist training. Endoscopy services, the mainstay of gastroenterology in the West, are in their infancy in many developing countries. The challenges faced by those setting up a service are illustrated by the example of a Nigerian endoscopy unit. Finally, we highlight the limited scope of many clinical guidelines produced in western countries. Guidelines which take account of resource limitations in the form of “cascades” are advocated in order to make these guidelines truly global. Recognition of the different working conditions facing practitioners worldwide is an important step towards narrowing the gap between gastroenterology in rich and poor countries. PMID:19533805
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US Clean Development Mechanism: benefits of the CDM for developing countries
Energy Technology Data Exchange (ETDEWEB)
Pearce, D.; Day, B.; Newcombe, J.; Brunello, T.; Bello, T.
1998-11-01
The Kyoto Protocol to the Framework Convention on Climate Change enables countries with mandatory greenhouse gas reduction commitments to offset some of their domestic emissions by reductions in emissions and enhancement of carbon sinks in other countries. One of three types of offsets in the Protocol is the Clean Development Mechanism, a form of joint implementation between Annex 1 and non-Annex 1 countries which stresses the development gains to developing countries (Article 12). This report focuses on the provision of Article 12 and aims to establish a framework for determining the net benefits of such offsets or trades to developing countries. It looks at some estimates of the likely size of the CDM market, addresses the issue of risks, and takes a brief look at the issue of sharing credits between hosts and investors. It addresses how CDM projects might be screened for their contribution to sustainable development in developing countries and introduces the framework for assessing that contribution and then applies that framework to evaluate different types of potential CDM projects (in the energy, transport, forests and agricultural sectors). 63 refs., 8 figs., 387 tabs., 7 apps.
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Jayasekara, Rasika; Schultz, Tim
2006-09-01
Objectives The objective of this review was to appraise and synthesise the best available evidence on the feasibility and appropriateness of introducing nursing curricula from developed countries into developing countries. Inclusion criteria This review considered quantitative and qualitative research papers that addressed the feasibility and appropriateness of introducing developed countries' nursing curricula into developing countries. Papers of the highest level of evidence rating were given priority. Participants of interest were all levels of nursing staff, nursing students, healthcare consumers and healthcare administrators. Outcomes of interest that are relevant to the evaluation of undergraduate nursing curricula were considered in the review including cost-effectiveness, cultural relevancy, adaptability, consumer satisfaction and student satisfaction. Search strategy The search strategy sought to find both published and unpublished studies and papers, limited to the English language. An initial limited search of MEDLINE and CINAHL was undertaken followed by an analysis of the text words contained in the title and abstract, and of the index terms used to describe the article. A second extensive search was then undertaken using all identified key words and index terms. Finally, the reference list of all identified reports and articles was searched, the contents pages of a few relevant journals were hand searched and experts in the field were contacted to find any relevant studies missed from the first two searches. Methodological quality Each paper was assessed by two independent reviewers for methodological quality before inclusion in the review using an appropriate critical appraisal instrument from the System for the Unified Management, Assessment and Review of Information (SUMARI) package. Results A total of four papers, including one descriptive study and three textual papers, were included in the review. Because of the diverse nature of
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Strategies for Fighting Pandemic Flu in Developing Countries
Centers for Disease Control (CDC) Podcasts
2009-03-04
Countries throughout the world are preparing for the next influenza pandemic. Developing countries face special challenges because they don't have antiviral drugs or vaccines that more developed countries have. In this podcast, CDC's Dr. Dan Jernigan discusses new and innovative approaches that may help developing countries fight pandemic flu when it emerges. Created: 3/4/2009 by Emerging Infectious Diseases. Date Released: 3/4/2009.
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Developing countries inclined to nuclear energy. Advent of newcomer countries age
International Nuclear Information System (INIS)
Kobayashi, Masaharu
2017-01-01
Although a certain degree of braking was applied to the nuclear power development of the world after the accident of TEPCO Fukushima Daiichi Nuclear Power Station in 2011, many countries maintain the attitude of promoting nuclear power from the viewpoints of global environmental issues and energy security. This paper overviews the trends of nuclear power generation around the world, and then introduces the nuclear power situation of the nuclear power generation countries such as Finland, Germany, Switzerland, Ukraine, Argentina, and Taiwan. In Germany, nuclear departure policy since before the Fukushima Daiichi accident was accelerated, and the nuclear phase-out law was passed and put into force in August 2011. This paper also introduces the nuclear development trends in the newly introducing countries of United Arab Emirates (UAE), Belarus, Bangladesh, Turkey, Vietnam, and Saudi Arabia. Iran's first Bushehr No.1 unit began operation in 2013, and in the future United Arab Emirates will join in 2018 and Belarus will join 2019 as the nuclear power generation country. In the 2020s, several more countries are expected to newly join. (A.O.)
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Prospects of Nuclear Power for Developing Countries
International Nuclear Information System (INIS)
Mourogov, V. M.; Khan, A. M.; Rogner, H-H.; Kagramanian, V. S.
1998-01-01
The demand for electricity in developing countries of the world is expected to grow rapidly in the coming decades as these countries undergo the process of industrialization, accompanied by increased urbanization, and seek to improve the living standards of their growing population. The continued heavy reliance of the power sector on fossil fuels will result in an increased dependence of a number of the developing countries on energy imports, with consequentbalance of payment difficulties and implications in terms of reduced energy security, cause severe degradation of the local and regional environment, and will also lead to increasing emissions of greenhouse gases. Increasing the share of hydropower in most of the developing countries is constrained by the limited potential of hydro resources as well as environmental considerations. Other renewable energy technologies such as solar PV and wind power are not expected to play a significant role in the commercial supply of electricity in the foreseeable future in the most part of the developing world. Thus nuclear power as a non-fossil alternative with a proven and mature technology may be called upon to play an increasing role in the future supply of electricity to developing countries. The paper discusses the main factors that are likely to affect, both positively and negatively, the deployment of nuclear power in developing countries and presents the results of the recent IAEA projections on nuclear power capacity growth up to the 2020. The paper also briefly reviews the prospects of nuclear power in Central and Eastern European countries. (author)
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Fostering biotechnology entrepreneurship in developing countries
African Journals Online (AJOL)
Fred
countries cheaper and potentially easier to administer. Efficient sewage treatment ... developing countries, start-up funding for biotechnology companies is still very ... Business incubators are unique in stimulating spin-offs from universities and ...
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Development perspective of transitional countries
Directory of Open Access Journals (Sweden)
Ilić Bogdan B.
2005-01-01
Full Text Available The end of 20th century witnessed the affirmation and development of information technology as well as the transformation of industrial into information, "new economy", which caused changes in people and circumstances. The role and importance of nonhuman factors was increased, causing entrepreneurship and knowledge-based information to become the most significant resources. The Internet became the basis of the "new economy". It changes the way of doing business, studying, researching, communicating and competition. It also reduces operating costs, crosses national borders and leads to the globalization of the world economy. Transitional countries have to fit into modern development flows by formulating their own strategy of national development and establishing their own competitive advantages in conditions of "new economy". These advantages lie predominantly in highly qualified and skilled younger labor which learns fast and adopts new knowledge and skills, through reducing transactional costs, shortening of certain development stages through which developed countries have already gone, using their experience, scientific-technological progress, a rise in work productivity, etc. Experience of other countries should be innovated and adapted to one's own material and social conditions, not copied. This enables the emergence of "European small tigers", which are similar to "Asian small tigers".
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THE FASTEST GROWING LEAST DEVELOPED COUNTRIES
Directory of Open Access Journals (Sweden)
Wioletta NOWAK
2017-12-01
Full Text Available The paper presents trends in economic growth and development in twelve least developed countries from 2006 to 2015. The study is based on the data retrieved from the World Bank Database. During the analysed 10 years, seven Asian (Myanmar, Lao PDR, Bhutan, Cambodia, Timor-Leste, Bangladesh, and Afghanistan and five African (Ethiopia, Rwanda, Angola, Sudan, and Mozambique LDCs had average annual GDP per capita growth rates higher than 4.0%. GDP has been largely generated through the services and industry sectors. A few LDCs sustained strong growth mainly because of foreign assistance and in other countries remittances were a significant source of development finance. Resource rich countries recorded high inflows of foreign direct investment. In a few fast growing LDCs the state has been heavily engaged in economy. The analysed LDCs substantially improved their development indicators.
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DEVELOPING COUNTRIES. TRANSITION ECONOMIES
Directory of Open Access Journals (Sweden)
Dumitru FILIPEANU
2016-05-01
Full Text Available According to the modern theories of economic development – the take-off, backwardness, convergence and balanced growth hypothesis - the new industrialized states from Asia seem to have noticed the advantages of backwardness from which low income countries benefited, namely the possibility to take advantage of the latest technological discoveries of advanced countries, thus achieving a faster growth than the latter which operated closer to the technological border. The assimilation of appropriate technologies, however, required the efficient mobilization and allocation of resources and the improvement of human and physical capital. While the Western countries were confronted with crises generated by inflationary shocks and movements of speculative capital, the relative isolation of countries whose economy was planned by the world economy sheltered them until 1990, unemployment being practically non-existent. Asia's exceptional economic success is not only due to borrowing Western practices, but also to the fact that Asian societies maintained certain traditional features of their own culture - such as a strong work ethic - and integrated them in the modern business environment.
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Analysis of Public Sector Efficiency in Developed Countries
Directory of Open Access Journals (Sweden)
Ivan Lovre
2017-06-01
Full Text Available The public sector in developed countries went through various forms of transformation in the twentieth century. The expansion of the public sector resulted in high levels of public spending in developed countries. The financial crisis of 2008 led to recessions in the economies of developed countries, the public debt growth, and actualized the issue of the public sector optimal size and efficiency. This study analysed the public sector efficiency in 19 developed countries. The analysis focuses on the relationship between the size of public expenditure and economic growth in the global financial crisis and the measures implemented. The aim of the research in this paper is a comparison of total and partial efficiency of the public sector in developed countries, in order to determine the characteristics of the public sector operations. The comparison covers the areas of the public sector operations in order to identify sources of inefficiency. Partial and overall efficiency of countries are analysed with different size and concept of the public sector, to determine the relationship between the public sector size, efficiency and welfare of citizens. The research results clearly indicate (unjustified state intervention in developed countries.
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Helminthic therapy: using worms to treat immune-mediated disease.
Elliott, David E; Weinstock, Joel V
2009-01-01
There is an epidemic of immune-mediated disease in highly-developed industrialized countries. Such diseases, like inflammatory bowel disease, multiple sclerosis and asthma increase in prevalence as populations adopt modern hygienic practices. These practices prevent exposure to parasitic worms (helminths). Epidemiologic studies suggest that people who carry helminths have less immune-mediated disease. Mice colonized with helminths are protected from disease in models of colitis, encephalitis, Type 1 diabetes and asthma. Clinical trials show that exposure to helminths reduce disease activity in patients with ulcerative colitis or Crohn's disease. This chapter reviews some of the work showing that colonization with helminths alters immune responses, against dysregulated inflammation. These helminth-host immune interactions have potentially important implications for the treatment of immune-mediated diseases.
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Promoting Balanced Competitiveness Strategies of Firms in Developing Countries
Wang, Vivienne
2012-01-01
Since the pioneering work of Joseph Schumpeter (1942), it has been assumed that innovations typically play a key role in firms’ competitiveness. This assumption has been applied to firms in both developed and developing countries. However, the innovative capacities and business environments of firms in developing countries are fundamentally different from those in developed countries. It stands to reason that innovation and competitiveness models based on developed countries may not apply to developing countries. In this volume, Vivienne Wang and Elias G. Carayannis apply both theoretical approaches and empirical analysis to explore the dynamics of innovation in developing countries, with a particular emphasis on R&D in manufacturing firms. In so doing, they present an alternative to Michael Porter’s Competitive Advantage Model—a Competitive Position Model that focuses on incremental and adaptive innovations that are more appropriate than radical innovations for developing countries. Their ...
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Ovnat Tamir, Sharon; Shemesh, Shay; Oron, Yahav; Marom, Tal
2017-05-01
Acute otitis media (AOM) is a common childhood disease, with an enormous economic and healthcare-related burden. Guidelines and consensus papers for AOM diagnosis and management were published in many countries. Our objective was to study the differences and similarities between these protocols in developing and developed countries. The keywords: 'acute otitis media' AND 'children' AND ['treatment' or 'management'] AND ['guideline' or 'consensus'] were used in various electronic databases between 1 January 1989 through 31 December 2015. Overall, 99 sources from 62 countries were retrieved: 53 from 22 developed countries, and 46 from 40 developing countries. Representative guidelines from America (the USA, Argentina), Europe (Italy, Moldova), Africa (South Africa, Tanzania, Ethiopia), Asia (Japan, Afghanistan, Sri Lanka),and Oceania (South Australia, Fiji) were compared. Paediatric societies publish guidelines in most developed countries; in developing countries, the Ministry of Health usually initiates guideline formulation. Most guidelines use the same diagnostic criteria and offer watchful waiting in mild-moderate scenarios. Amoxicillin is the suggested first-line antibiotic, whereas options for second-line and third-line therapies vary. Duration of therapy varies and is usually age dependent: 5-7 days for children 2 years in developed countries, while duration and age groups vary greatly in developing countries. Reduction of AOM risk factors is encouraged in developed countries, but rarely in developing countries. Guidelines for AOM from developing and developed countries are similar in many aspects, with variation in specific recommendations, due to local epidemiology and healthcare accessibility. Formulation of regional guidelines may help reduce AOM burden. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.
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Nuclear project finance in developing countries: The multi-country financing alternative
International Nuclear Information System (INIS)
Fleck, J.B.
1986-01-01
It is the basic contention of this paper that, because of certain factors in the financial markets, multi-country financing (MCF) is the new alternative if not the imperative for large scale and turnkey nuclear plant programs in developing countries. The point is made that its successful use depends on the ability of the host country, the credit granting countries and suppliers to both recognize the MCF reality and manage its implicit variables. Those who collectively do so will be successful, and those who cannot will not be states the author. The aspects of MCF are described
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Sanderson, Matthew
2010-01-01
Contemporary levels of international migration in less-developed countries are raising new and important questions regarding the consequences of immigration for human welfare and well-being. However, there is little systematic cross-national evidence of how international migration affects human development levels in migrant-receiving countries in…
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Destigmatizing day-to-day practices: what developed countries can learn from developing countries.
Rosen, Alan
2006-02-01
The nature of and threshold for stigma associated with mental disorders appears to be different between developed and developing countries. Decreasing stigma can be achieved through a combination of the best Western educational and media strategies and the systematization of some important lessons from developing countries. At the macro-level, this involves: societal changes leading to being more inclusive and re-integrating people with mental illness into our communities; finding socially useful and culturally valued work roles for such marginalized people; re-extending our kinship networks, and re-valuing contact with people with mental illness and learning from their experiences. At the micro-level, this involves developing more destigmatizing day-to-day clinical practices, including: more holistic appraisal of disorder, abilities and needs; therapeutic optimism; a strengths orientation; engaging family and redeveloping an extended support network; celebration of age appropriate rites of passage; invoking the language of recovery; valuing veterans of mental illness as "spirit guides"; promoting consumers' community living as full citizens; engaging and involving the local community in taking responsibility for their own mental health.
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Space-based Communications Infrastructure for Developing Countries
Barker, Keith; Barnes, Carl; Price, K. M.
1995-01-01
This study examines the potential use of satellites to augment the telecommunications infrastructure of developing countries with advanced satellites. The study investigated the potential market for using satellites in developing countries, the role of satellites in national information infractructures (NII), the technical feasibility of augmenting NIIs with satellites, and a nation's financial conditions necessary for procuring satellite systems. In addition, the study examined several technical areas including onboard processing, intersatellite links, frequency of operation, multibeam and active antennas, and advanced satellite technologies. The marketing portion of this study focused on three case studies: China, Brazil, and Mexico. These cases represent countries in various stages of telecommunication infrastructure development. The study concludes by defining the needs of developing countries for satellites, and recommends steps that both industry and NASA can take to improve the competitiveness of U.S. satellite manufacturing.
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Teran, Rommy; Mitre, Edward; Vaca, Maritza; Erazo, Silvia; Oviedo, Gisela; Hübner, Marc P; Chico, Martha E; Mattapallil, Joseph J; Bickle, Quentin; Rodrigues, Laura C; Cooper, Philip J
2011-03-01
The immune response that develops in early childhood underlies the development of inflammatory diseases such as asthma and there are few data from tropical Latin America (LA). This study investigated the effects of age on the development of immunity during the first 5 years of life by comparing innate and adaptive immune responses in Ecuadorian children aged 6-9 months, 22-26 months, and 48-60 months. Percentages of naïve CD4+ T cells declined with age while those of memory CD4(+) and CD8(+) T cells increased indicating active development of the immune system throughout the first five years. Young infants had greater innate immune responses to TLR agonists compared to older children while regulatory responses including SEB-induced IL-10 and percentages of FoxP3(+) T-regulatory cells decreased with age. Enhanced innate immunity in early life may be important for host defense against pathogens but may increase the risk of immunopathology. Copyright © 2010 Elsevier Inc. All rights reserved.
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Investment in Developing Countries
Motooka, Takeshi
1973-01-01
The fundamental problems of investment in rural education in the present developing countries are analyzed. Needs of rural education are outlined and financial considerations related to investment in the improvement of rural educational programs are discussed. (SM)
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Implementing care policy in developing countries
International Nuclear Information System (INIS)
Tattum, L.; Phishner, E.S.
1992-01-01
How do chief executives of Western companies, from their plush offices, keep tabs on what happens at chemical plants in developing countries? Many point out that it is difficult to operate a Responsible Care policy in countries where industry associations have not yet started a coordinated initiative. 'Responsible Care is a program that has primarily a geographic dimension and is organized country by country by the industry associations,' note Kaspar Eigenmann, head of corporate unit safety and environment at Ciba (Basel). Where there is a campaign, the local Ciba company participates, he says. 'It's obvious that the industrialized countries are taking the lead,' adds Eigenmann
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Promoting nuclear medicine in developing countries
International Nuclear Information System (INIS)
Ganatra, R.; Nofal, M.
1986-01-01
After a short review of the applications of nuclear medicine in diagnosis and treatment of diseases or in medical research the ways and the means of IAEA's support in helping developing countries to set up nuclear medicine capabilities in their hospitals are described. Some trends and new directions in the field of nuclear medicine and the problems related to the implementation of these techniques in developing countries are presented
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Global Agricultural Trade and Developing Countries
Aksoy, M. Ataman; Beghin, John C.
2005-01-01
Global Agricultural Trade and Developing Countries explores the outstanding issues in global agricultural trade policy and evolving world production and trade patterns. This book presents research findings based on a series of commodity studies of significant economic importance to developing countries. Setting the stage with background chapters and investigations of cross-cutting issues, the authors describe trade and domestic policy regimes affecting agricultural and food markets and analyz...
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Waste biorefineries: Enabling circular economies in developing countries.
Nizami, A S; Rehan, M; Waqas, M; Naqvi, M; Ouda, O K M; Shahzad, K; Miandad, R; Khan, M Z; Syamsiro, M; Ismail, I M I; Pant, Deepak
2017-10-01
This paper aims to examine the potential of waste biorefineries in developing countries as a solution to current waste disposal problems and as facilities to produce fuels, power, heat, and value-added products. The waste in developing countries represents a significant source of biomass, recycled materials, chemicals, energy, and revenue if wisely managed and used as a potential feedstock in various biorefinery technologies such as fermentation, anaerobic digestion (AD), pyrolysis, incineration, and gasification. However, the selection or integration of biorefinery technologies in any developing country should be based on its waste characterization. Waste biorefineries if developed in developing countries could provide energy generation, land savings, new businesses and consequent job creation, savings of landfills costs, GHG emissions reduction, and savings of natural resources of land, soil, and groundwater. The challenges in route to successful implementation of biorefinery concept in the developing countries are also presented using life cycle assessment (LCA) studies. Copyright © 2017 Elsevier Ltd. All rights reserved.
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Problems facing developing countries
International Nuclear Information System (INIS)
Anon.
1986-01-01
Financing, above all political and technical considerations, remains the major obstacle faced by developing countries who wish to embark on a nuclear power programme. According to the IAEA, the support of the official lending agencies of the suppliers is essential. (author)
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Verguet, Stéphane; Johri, Mira; Morris, Shaun K; Gauvreau, Cindy L; Jha, Prabhat; Jit, Mark
2015-03-03
The Measles & Rubella Initiative, a broad consortium of global health agencies, has provided support to measles-burdened countries, focusing on sustaining high coverage of routine immunization of children and supplementing it with a second dose opportunity for measles vaccine through supplemental immunization activities (SIAs). We estimate optimal scheduling of SIAs in countries with the highest measles burden. We develop an age-stratified dynamic compartmental model of measles transmission. We explore the frequency of SIAs in order to achieve measles control in selected countries and two Indian states with high measles burden. Specifically, we compute the maximum allowable time period between two consecutive SIAs to achieve measles control. Our analysis indicates that a single SIA will not control measles transmission in any of the countries with high measles burden. However, regular SIAs at high coverage levels are a viable strategy to prevent measles outbreaks. The periodicity of SIAs differs between countries and even within a single country, and is determined by population demographics and existing routine immunization coverage. Our analysis can guide country policymakers deciding on the optimal scheduling of SIA campaigns and the best combination of routine and SIA vaccination to control measles. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.
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Pharmacovigilance in developing countries (part I): importance and challenges.
Elshafie, Shaimaa; Zaghloul, Iman; Roberti, Anne Marie
2017-12-16
The thalidomide disaster was the significant historical event that acted as a catalyst for pharmacovigilance activity. Following this event developed countries initiated drug monitoring systems that evolved and now extend their scope to broader drug-related safety issues; however, this was not the case in developing countries. Pharmacovigilance is still a relatively new concept with low priority in developing countries although various issues are raising concerns that magnify the need for systems to monitor post marketing drug safety in these countries. This article analyzes the barriers to introducing robust pharmacovigilance systems in developing countries.
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Radioassay services in developing countries
International Nuclear Information System (INIS)
Belcher, E.H.
1978-01-01
The findings and recommendations of an advisory group convened by the IAEA to give guidance relating to the development of IAEA projects involving radioassay are presented. The current status of radioassay services in different countries is reviewed; guiding principles relating to the organization of such services are affirmed, with particular reference to services in developing countries; the needs of services at various levels as regards accommodation, staff, equipment, supporting services and running costs, including minimum initial needs, are specified; operational problems are identified and indications given how they may be solved; facilities for training in radioassay are reviewed; finally, reference is made to IAEA activities in the field in question. (author)
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Progress in the developing countries
International Nuclear Information System (INIS)
Simnad, M.
1981-01-01
Nuclear programmes in selective developing countries are briefly discussed. The oil rich countries of Iraq, Libya and Iran all have reactors on order. Turkey has decided to purchase a PWR from the USSR and Egypt's programme anticipates a capacity of 6600 MWe by 2000. The current projections for India are 6000 MWe by 1990 and 20,000 MWe by 2000. The progress of Pakistan, South Korea and other Asian countries are discussed. The predicted growth in reactors and population in Latin America is considered - 17 reactors presently planned for a population of 340 million and 18-57 possible additions in 2000 for an estimated population of 600 million. The role of the IAEA and experience of some Western countries in technology transfer is discussed with the ambitious Spanish nuclear power programme and the experience of Argentina in purchasing Candu reactors. (author)
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Capacity Development for Sustainable Urban Transportation in Developing Countries
Senbil, Metin; Fujiwara, Akimasa; Zhang, Junyi
2008-01-01
To make urban transport sustainable, effective and efficient, first and foremost, there is a need for capacity development-capacity is defined as the ability to deal with problems in efficient and effective ways-in developing countries. Apart from many important capacity related problems such as lack of adequate infrastructure, older vehicle population, etc., policy makers in developing countries have to consider changing individual behavior to realize sustainable urban transportation policie...
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Skilled migration and health outcomes in developing countries.
Uprety, Dambar
2018-04-30
Many studies have found that health outcomes decline when health professionals leave the country, but do such results remain consistent in gender- and income-disaggregated skilled migration? To help uncover explanations for such a pro-migration nature of health outcomes, the present study revisits this topic but allows for associations of skilled migration with mortality and life expectancy to differ between male and female, and between low- and high-income countries. Using a panel of 133 developing countries as source and 20 OECD countries as destination from 1980 to 2010 allowing the coefficient on emigration across different education levels to differ, the study finds the negative effect of high-skilled emigration on health outcomes. Such effect is more pronounced for high-skilled female migration than those for male and for low-income countries than for middle-and high-income countries. Results also show that such adverse effect is larger for African countries than non-African ones. However, the low-skilled migration appears to be insignificant to affect health outcomes in developing countries. Thus, skilled migration is detrimental to longevity in developing countries but unskilled migration is not.
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Road safety in developing countries: The role of research.
Schreuder, D.A.
1986-01-01
Road accidents are a continuous burden for all countries, developing and developed alike. There are reasons, however, to pay special attention to developing countries as the situation often seems to be more unfavourable as in developed countries, and as the consequences of road accidents, can be
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Innovation in Developing Countries - a New Approach
Directory of Open Access Journals (Sweden)
Dagmara Bubel
2015-05-01
Full Text Available Currently the enterprises’ development and competitive positions are determined by innovation. The importance of innovation in corporate management is a result of changes in corporate environment, as well as of preferences and changing needs of customers. These changes are accompanied by a new approach to innovation: they are no longer limited to developed countries, but also emerge in developing countries. Moreover, a reverse in the direction of innovations occurs, which means that developing countries are often not only the recipients of innovative products, but also creators and „exporters”. Given the current trends, the paper begins with the concept of innovation and deals with the subject of innovation in developing countries. The conclusion of the paper presents examples of innovative solutions originated from Poland. Although Poland ranks rather „tail end” in innovation rankings, but also deliver products that have a good chance to conquer the global market. By highlighting the importance of this reverse innovative trend, this article provides the conceptual grounds for further systematic research.
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Market Dynamics and Productivity in Developing Countries ...
International Development Research Centre (IDRC) Digital Library (Canada)
25 nov. 2009 ... Market Dynamics and Productivity in Developing Countries : Economic Reforms in the Middle East and North Africa. Book cover Market Dynamics and Productivity in Developing Countries: Economic Reforms in the Middle East. Directeur(s):. Khalid Sekkat. Maison(s) d'édition: Springer, CDRI. 25 novembre ...
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Practice of nuclear medicine in a developing country
International Nuclear Information System (INIS)
Hasan, M.M.; Karim, M.A.; Nahar, N.; Haque, M.M.
2002-01-01
For more than a half a century nuclear medicine is contributing in the field of medicine. Still nuclear medicine is not widely available in many countries. Especially in developing countries due to many a reasons nuclear medicine could not flourish in that way. Availability of radioisotope, high cost of instrument and sophistication of the branch are the three main reasons behind. Even the countries where nuclear medicine is functioning for quite a long time, the facilities for proper function are still not adequate. Training of manpower, maintenance of instruments, regular supply of isotopes and kit and cost effectiveness are some of the major problems. We have seen some fast developments in nuclear medicine in last few decades. Development of gamma detecting systems with SPECT, positron emission detector (PET), supported computer technology and introduction of some newer radiopharmaceuticals for functional studies are few of the examples. The developing countries also have a problem to go on parallel with these rapid development of nuclear medicine in other part of the world. In last few decades we have also witnessed development of CT, MRI, Ultrasound and other imaging modalities as our competitor. Specially for developing countries these have posed as a major challenge for nuclear medicine. A better understanding between developed and developing nations is the key point of todays ultimate success in any sector. For real development of nuclear medicine and to give the majority of the people the benefit of nuclear medicine a better and more active co-operation is needed between all the countries. The paper presents the difficulties and some practical problems of practicing nuclear medicine in a developing country. And also appeals for global co-operation to solve the problems for better interest of the subject
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Synchrotron light sources in developing countries
Mtingwa, Sekazi K.; Winick, Herman
2018-03-01
We discuss the role that synchrotron light sources, such as SESAME, could play in improving the socioeconomic conditions in developing countries. After providing a brief description of a synchrotron light source, we discuss the important role that they played in the development of several economically emerging countries. Then we describe the state of synchrotron science in South Africa and that country’s leadership role in founding the African Light Source initiative. Next, we highlight a new initiative called Lightsources for Africa, the Americas & Middle East Project, which is a global initiative led by the International Union of Pure and Applied Physics and the International Union of Crystallography, with initial funding provided by the International Council for Science. Finally, we comment on a new technology called the multibend achromat that has launched a new paradigm for the design of synchrotron light sources that should be attractive for construction in developing countries.
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Consumer evaluations of products from developing countries
Verlegh, P.W.J.
2002-01-01
Consumers use country of origin as a signal or proxy for product quality. Consumers have little confidence in the ability of less developed countries to produce high quality goods. On the other hand emotionally attachment to a country or associations of "exoticness" or "authenticity" can lead to a
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Industry Switching in Developing Countries
DEFF Research Database (Denmark)
Newman, Carol; Rand, John; Tarp, Finn
Firm turnover (i.e. firm entry and exit) is a well-recognized source of sectorlevel productivity growth across developing and developed countries. In contrast, the role and importance of firms switching activities from one sector to another is little understood. Firm switchers are likely...
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Road safety in developing countries.
Schreuder, D.A.
1991-01-01
This paper presents a classification of countries (developing and developed alike), divided into two main categories: an economical and historical entry. When road safety problems are placed into the economical context, it then appears that, among other things: (1) The road safety problem in the
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Obesity and poverty paradox in developed countries.
Żukiewicz-Sobczak, Wioletta; Wróblewska, Paula; Zwoliński, Jacek; Chmielewska-Badora, Jolanta; Adamczuk, Piotr; Krasowska, Ewelina; Zagórski, Jerzy; Oniszczuk, Anna; Piątek, Jacek; Silny, Wojciech
2014-01-01
Obesity is a civilization disease and the proportion of people suffering from it continues to grow, especially in the developed countries. Number of obese people in Europe has increased threefold over the last 20 years. The paradox of obesity and poverty relationship is observed especially in the developed and developing countries. In developing countries, along with economic development and income growth, the number of people with overweight and obesity is increasing. This paradox has a relationship with both the easy availability and low cost of highly processed foods containing 'empty calories' and no nutritional value. To date, this paradox has been described in the United States and the United Kingdom, although many European countries are also experiencing high percentages of obese people. Among the reasons for the growing obesity in the population of poor people are: higher unemployment, lower education level, and irregular meals. Another cause of obesity is low physical activity, which among the poor is associated with a lack of money for sports equipment. Due to the large rate of deaths caused by diseases directly linked to obesity, the governments of many countries implement prevention programmes of overweight and obesity. These programmes are based primarily on educating the public about a healthy lifestyle based on healthy eating, daily physical activity and avoiding alcohol and cigarettes.
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Obesity and poverty paradox in developed countries
Directory of Open Access Journals (Sweden)
Wioletta Żukiewicz-Sobczak
2014-09-01
Full Text Available Obesity is a civilization disease and the proportion of people suffering from it continues to grow, especially in the developed countries. Number of obese people in Europe has increased threefold over the last 20 years. The paradox of obesity and poverty relationship is observed especially in the developed and developing countries. In developing countries, along with economic development and income growth, the number of people with overweight and obesity is increasing. This paradox has a relationship with both the easy availability and low cost of highly processed foods containing ‘empty calories’ and no nutritional value. To date, this paradox has been described in the United States and the United Kingdom, although many European countries are also experiencing high percentages of obese people. Among the reasons for the growing obesity in the population of poor people are: higher unemployment, lower education level, and irregular meals. Another cause of obesity is low physical activity, which among the poor is associated with a lack of money for sports equipment. Due to the large rate of deaths caused by diseases directly linked to obesity, the governments of many countries implement prevention programmes of overweight and obesity. These programmes are based primarily on educating the public about a healthy lifestyle based on healthy eating, daily physical activity and avoiding alcohol and cigarettes.
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INTEREST RATE DERIVATIVES IN DEVELOPING COUNTRIES IN EUROPE
SLOBODAN CEROVIC; MARINA PEPIC
2011-01-01
Financial derivatives (interest rate futures, options and swaps) are a very simple way to minimize interest rate risk and therefore are extremely popular. The value of interest rate derivatives transactions in the world is increasing dramatically. Unfortunately, this is not the case with developing countries in Europe. Although significantly increased in the last decade, interest rate derivatives markets in developing countries are still in nascent stage. In most developing countries still t...
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Surgical audit in the developing countries.
Bankole, J O; Lawal, O O; Adejuyigbe, O
2003-01-01
Audit assures provision of good quality health service at affordable cost. To be complete therefore, surgical practice in the young developing countries, as elsewhere, must incorporate auditing. Peculiarities of the developing countries and insufficient understanding of auditing may be, however, responsible for its been little practised. This article, therefore, reviews the objectives, the commonly evaluated aspects, and the method of audit, and includes a simple model of audit cycle. It is hoped that it will kindle the idea of regular practice of quality assurance by surgeons working in the young developing nations and engender a sustainable interest.
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Systems approaches to integrated solid waste management in developing countries
International Nuclear Information System (INIS)
Marshall, Rachael E.; Farahbakhsh, Khosrow
2013-01-01
Highlights: ► Five drivers led developed countries to current solid waste management paradigm. ► Many unique factors challenge developing country solid waste management. ► Limited transferability of developed country approaches to developing countries. ► High uncertainties and decision stakes call for post-normal approaches. ► Systems thinking needed for multi-scale, self-organizing eco-social waste systems. - Abstract: Solid waste management (SWM) has become an issue of increasing global concern as urban populations continue to rise and consumption patterns change. The health and environmental implications associated with SWM are mounting in urgency, particularly in the context of developing countries. While systems analyses largely targeting well-defined, engineered systems have been used to help SWM agencies in industrialized countries since the 1960s, collection and removal dominate the SWM sector in developing countries. This review contrasts the history and current paradigms of SWM practices and policies in industrialized countries with the current challenges and complexities faced in developing country SWM. In industrialized countries, public health, environment, resource scarcity, climate change, and public awareness and participation have acted as SWM drivers towards the current paradigm of integrated SWM. However, urbanization, inequality, and economic growth; cultural and socio-economic aspects; policy, governance, and institutional issues; and international influences have complicated SWM in developing countries. This has limited the applicability of approaches that were successful along the SWM development trajectories of industrialized countries. This review demonstrates the importance of founding new SWM approaches for developing country contexts in post-normal science and complex, adaptive systems thinking
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Systems approaches to integrated solid waste management in developing countries
Energy Technology Data Exchange (ETDEWEB)
Marshall, Rachael E., E-mail: rmarsh01@uoguelph.ca [School of Engineering, University of Guelph, Albert A. Thornbrough Building, Guelph, ON, Canada N1G 2W1 (Canada); Farahbakhsh, Khosrow, E-mail: khosrowf@uoguelph.ca [School of Engineering, University of Guelph, Albert A. Thornbrough Building, Guelph, ON, Canada N1G 2W1 (Canada)
2013-04-15
Highlights: ► Five drivers led developed countries to current solid waste management paradigm. ► Many unique factors challenge developing country solid waste management. ► Limited transferability of developed country approaches to developing countries. ► High uncertainties and decision stakes call for post-normal approaches. ► Systems thinking needed for multi-scale, self-organizing eco-social waste systems. - Abstract: Solid waste management (SWM) has become an issue of increasing global concern as urban populations continue to rise and consumption patterns change. The health and environmental implications associated with SWM are mounting in urgency, particularly in the context of developing countries. While systems analyses largely targeting well-defined, engineered systems have been used to help SWM agencies in industrialized countries since the 1960s, collection and removal dominate the SWM sector in developing countries. This review contrasts the history and current paradigms of SWM practices and policies in industrialized countries with the current challenges and complexities faced in developing country SWM. In industrialized countries, public health, environment, resource scarcity, climate change, and public awareness and participation have acted as SWM drivers towards the current paradigm of integrated SWM. However, urbanization, inequality, and economic growth; cultural and socio-economic aspects; policy, governance, and institutional issues; and international influences have complicated SWM in developing countries. This has limited the applicability of approaches that were successful along the SWM development trajectories of industrialized countries. This review demonstrates the importance of founding new SWM approaches for developing country contexts in post-normal science and complex, adaptive systems thinking.
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Developing countries and the frontiers of science and technology
Energy Technology Data Exchange (ETDEWEB)
Gunawardena, W
1980-06-01
Direct transfers of technology to developing countries are basically product transfers which may be irrelevant to the recipient country's needs. The process of imitation, however, can build upon local research aided by information transfers so that innovative technology is applied more appropriately. Since developing countries think of technology transfer as a purchased package rather than an intellectual process, most Third World countries have a low innovative capacity at present. This can be overcome if the developed countries will cooperate with information transfers. 24 references. (DCK)
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Development of CD4 T cell dependent immunity against N. brasiliensis infection
Directory of Open Access Journals (Sweden)
Marina eHarvie
2013-03-01
Full Text Available Of all the microbial infections relevant to mammals the relationship between parasitic worms and what constitutes and regulates a host protective immune response is perhaps the most complex and evolved. Nippostrongylus brasiliensis is a tissue migrating parasitic roundworm of rodents that exemplifies many of the salient features of parasitic worm infection, including parasite development through sequential larval stages as it migrates through specific tissue sites. Immune competent hosts respond to infection by N. brasiliensis with a rapid and selective development of a profound Th2 immune response that appears able to confer life long protective immunity against reinfection. This review details how the lung can be the site of migrating nematode immune killing and the gut a site of rapid immune mediated clearance of worms. Furthermore it appears that N. brasiliensis induced responses in the lung are sufficient for conferring immunity in lung and gut while infection of the gut only confers immunity in the gut. This review also covers the role of IL-4, STAT6 and the innate cytokines IL-25, IL-33 and TSLP in the generation of CD4-mediated immunity against N. brasiliensis reinfection and discusses what cytokines might be involved in mediated killing or expulsion of helminth parasites.
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Postnatal Innate Immune Development: From Birth to Adulthood
Directory of Open Access Journals (Sweden)
Anastasia Georgountzou
2017-08-01
Full Text Available It is well established that adaptive immune responses are deficient in early life, contributing to increased mortality and morbidity. The developmental trajectories of different components of innate immunity are only recently being explored. Individual molecules, cells, or pathways of innate recognition and signaling, within different compartments/anatomical sites, demonstrate variable maturation patterns. Despite some discrepancies among published data, valuable information is emerging, showing that the developmental pattern of cytokine responses during early life is age and toll-like receptor specific, and may be modified by genetic and environmental factors. Interestingly, specific environmental exposures have been linked both to innate function modifications and the occurrence of chronic inflammatory disorders, such as respiratory allergies. As these conditions are on the rise, our knowledge on innate immune development and its modulating factors needs to be expanded. Improved understanding of the sequence of events associated with disease onset and persistence will lead toward meaningful interventions. This review describes the state-of-the-art on normal postnatal innate immune ontogeny and highlights research areas that are currently explored or should be further addressed.
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Likely impact of global warming on developing countries
International Nuclear Information System (INIS)
Topping, J.
1992-01-01
Over the last couple of years there has been mounting evidence that the human costs of rapid global warming are likely to be concentrated especially in developing countries and that some countries may be gravely affected. Climate impacts research has until recently been focused principally on a handful of more affluent countries, but studies of climate impacts on developing countries are now under way and preliminary results are likely to be available for many areas of the world within the next year
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National innovation system in less successful developing countries
DEFF Research Database (Denmark)
Intarakumnerd, Patarapong; Chairatana, Pun-arj; Tangchitpiboon, Tipawan
2002-01-01
This paper, using Thailand as a case study, aims at understanding the national innovation system (NIS) in developing countries which are less successful in technological catching-up. In contrast to developed countries, the development level of Thailand’s NIS does not link to its economic structural...... development level. As Thailand moves from agricultural to an increasingly industrial economy, its NIS remains weak and fragmented. The mismatch between the two affected Thailand’s competitiveness and partially contributed to the recent economic crisis. Studies of NIS in countries like Thailand should focus...
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Directory of Open Access Journals (Sweden)
Magda Kandil
2015-12-01
Full Text Available The paper studies determinants of flexibility of the nominal effective exchange rate and the effects of exchange rate shocks on macroeconomic variables and key components of the external balances using data for a sample of advanced and developing countries. The composite evidence points to the positive effects of appreciation through cheaper imports in support of higher growth and lower price inflation in advanced and developing countries. However, the negative effects of appreciation are more pervasive on the external balances in developing countries. The implication is developing countries remain highly dependent on exports of commodities. In contrast, advanced countries are more diversified and ahead in capitalizing on currency appreciation to mobilize investment growth, a channel that boosts competitiveness and mitigates the adverse effect of appreciation on external stability. The evidence attests to the need to create an environment that is more conducive to investment growth in developing countries.
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Missed Immunization Opportunities Among Children Under 5 Years Of Age Dwelling In Karachi City.
Khaliq, Asif; Sayed, Sayeeda Amber; Hussaini, Syed Abdullah; Azam, Kiran; Qamar, Mehak
2017-01-01
Immunization is the safest and effective measure for preventing and eradicating various communicable diseases. A glaring immunization gap exists between developing and industrialized countries towards immunization, because the developing countries including Pakistan are still striving to provide basic immunization to their children. The purpose of this study was to access the prevalence and factors of missing immunization among under 5-year children of Karachi.. A cross sectional study was conducted from June 2015 to October 2015 among different outpatient clinics of Karachi. Parents who had child less than 5 year of age were approached by non-probability purposive sampling. Data was analysed by using Statistical Package of Social Sciences. There were around 59.09% (n=156) and 64.43% (n=165) parents who have correctly responded regarding the number of essential immunization visit during the first and second year of their child life respectively. About 28.12% (n=108) parents responded that they do not know about the name and number of missed doses of vaccines. 31.78% (n=122) parents responded that their children have missed either one or more than one doses of routine immunization vaccines. Of which 34.42% (n=42) children have missed more than one vaccine. Lack of knowledge regarding immunization schedule 28.68% (n=34), concern about vaccine side effects 21.31%, (n=26), child sickness 17.21% (n=21), and lack of trust about government 10.65%, (n=13) were the major barriers identified by parents for missed immunization opportunities. Parents have inadequate knowledge regarding routine immunization visits, immunization schedule and vaccine doses. The practices of parents for routine childhood immunization are also poor. Parents refuse to immunize their child because of lack of immunization visit knowledge and also because of their doubts regarding vaccine potency and side effects. A proper system of immunization promotion, advocacy and reminder systems with proper
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The world economic development with the ISER-PIUS for developing and developed countries
International Nuclear Information System (INIS)
Wakabayashi, Hiroaki
1987-01-01
Nuclear power as a base for the world economic development has, unfortunately, been posing some potential risks including excessive radiation and radioactivity releases from the TMI-2 and the Chernobyl-4 as well as the future risks of nuclear waste management. On the other hand, it is a fact that nuclear power is already being used substantially as an economical energy option throughout the world. Therefore, the ISER-PIUS is now envissaged to be used eventually as safe and economical power source to be employed widely in the world. The present economic conditions and future economic development in Indonesia, taken as an example of less developed country, are described briefly. It is insisted that the policy of nuclear power introduction into a less developed country is neither economical nor realistic. More feasible seems a system of domestically designed and developed inherently safe reactor like ISER-PIUS. An analysis is also made of the future potential of such reactors in advanced countries in terms of the future of ISER-PIUS. It is concluded that cheap electricity and heat are needed for the economic development in less developed nations and for the maintenance of the economy level now attained by developed countries as well. International collaboration for the ISER-PIUS development will be a vehecle for the world-wide economic development in the next century. (Nogami, K.)
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Adaptation to Climate Change in Developing Countries
DEFF Research Database (Denmark)
Mertz, Ole; Halsnæs, Kirsten; Olesen, Jørgen E.
2009-01-01
Adaptation to climate change is given increasing international attention as the confidence in climate change projections is getting higher. Developing countries have specific needs for adaptation due to high vulnerabilities, and they will in this way carry a great part of the global costs...... of climate change although the rising atmospheric greenhouse gas concentrations are mainly the responsibility of industrialized countries. This article provides a status of climate change adaptation in developing countries. An overview of observed and projected climate change is given, and recent literature...... on impacts, vulnerability, and adaptation are reviewed, including the emerging focus on mainstreaming of climate change and adaptation in development plans and programs. The article also serves as an introduction to the seven research articles of this special issue on climate change adaptation in developing...
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Matee, Mecky I; Manyando, Christine; Ndumbe, Peter M; Corrah, Tumani; Jaoko, Walter G; Kitua, Andrew Y; Ambene, Herman Pa; Ndounga, Mathieu; Zijenah, Lynn; Ofori-Adjei, David; Agwale, Simon; Shongwe, Steven; Nyirenda, Thomas; Makanga, Michael
2009-07-20
European and Developing Countries Clinical Trials Partnership (EDCTP) was founded in 2003 by the European Parliament and Council. It is a partnership of 14 European Union (EU) member states, Norway, Switzerland, and Developing Countries, formed to fund acceleration of new clinical trial interventions to fight the human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS), malaria and tuberculosis (TB) in the sub-Saharan African region. EDCTP seeks to be synergistic with other funding bodies supporting research on these diseases. EDCTP promotes collaborative research supported by multiple funding agencies and harnesses networking expertise across different African and European countries. EDCTP is different from other similar initiatives. The organisation of EDCTP blends important aspects of partnership that includes ownership, sustainability and responds to demand-driven research. The Developing Countries Coordinating Committee (DCCC); a team of independent scientists and representatives of regional health bodies from sub-Saharan Africa provides advice to the partnership. Thus EDCTP reflects a true partnership and the active involvement and contribution of these African scientists ensures joint ownership of the EDCTP programme with European counterparts. The following have been the major achievements of the EDCTP initiative since its formation in 2003; i) increase in the number of participating African countries from two to 26 in 2008 ii) the cumulative amount of funds spent on EDCTP projects has reached 150 m euros, iii) the cumulative number of clinical trials approved has reached 40 and iv) there has been a significant increase number and diversity in capacity building activities. While we recognise that EDCTP faced enormous challenges in its first few years of existence, the strong involvement of African scientists and its new initiatives such as unconditional funding to regional networks of excellence in sub-Saharan Africa is envisaged to
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International: development, the petroleum, security for the least developing countries
International Nuclear Information System (INIS)
Anon.
2004-01-01
The annual report of the CNUCED presents the economic situation improvement of the developing countries, those which benefit from petroleum resources. The CNUCED worries on the durability of the economic improvement of these countries. (A.L.B.)
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CSR Institutionalized Myths in Developing Countries
DEFF Research Database (Denmark)
Jamali, Dima; Lund-Thomsen, Peter; Khara, Navjote
2017-01-01
This article examines joint action initiatives among small- and medium-sized enterprises (SMEs) in the manufacturing industries in developing countries in the context of the ascendancy of corporate social responsibility (CSR) and the proliferation of a variety of international accountability tools...... place, and how developing country firms can gain credit and traction by focusing on high visibility CSR issues, although the plight of workers remains fundamentally unchanged. The authors revisit these findings in the discussion and concluding sections, highlighting the main research and policy...
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International Nuclear Information System (INIS)
Oriada, R.; Byakagaba, A.; Kiza, M.; Magembe, M.
2010-01-01
Like Many African countries, Uganda is not Immune to the problem of illicit trafficking of Nuclear and Radioactive materials. This has been worsened by the porosity of the Ugandan Borders. There is control on the few Entry points and much of the border line does not have adequate control on what enters and leaves the country. Uganda is also used as a transit route with the neighboring countries like Sudan, Democratic Republic of Congo, Kenya,Tanzania.
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Developing countries and the global science Web
Cerdeira, Hilda; Fonda, Carlo; Cottrell, R L A
2003-01-01
Enabling scientists from developing countries to bridge the gap between rich and poor depends on closing another gap - the "digital divide". Now the technology exists to monitor this divide, and it reveals some alarming results. Most developing countries experience great difficulties because of adverse economic conditions and political instability, which means they lag behind in scientific and technological development. With the advent of the World Wide Web and the rapid exchange of information via the Internet, one might naively have thought that much of the gap between developed and developing nations would disappear, even if problems still persisted for those areas of science that need expensive facilities. However, access to information, peer reviewed or not, depends on having the appropriate hardware, i.e. a computer, and Internet connectivity, and there is a serious problem with access to the Internet in developing countries. Gaining access to a computer is more of a question of economics, and one that ...
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[AIDS, developing countries and ethnopsychiatry].
Ehrhardt, N; Defourny, J; Bertrand, J
1995-04-01
This work briefly assesses the history of the AIDS epidemic in different geographic regions and examines factors that render developing countries particularly vulnerable. It reviews the three main techniques of traditional therapeutic systems and examines their implications for psychiatric treatment of AIDS patients from developing countries. Young age structures, low rates of condom usage, women's lack of education and of sexual bargaining power, and the deficiencies of health and educational facilities are among factors that increase risks of HIV in developing countries. Health education geared to specific audiences should encourage condom use and other preventive measures. Among factors to encourage condom use, group decision making appears to be of greatest potential influence on behavior in sub-Saharan Africa and among African immigrants to Europe. To encourage preventive measures and to understand reactions of non-Western populations to HIV, it is desirable to understand the deeper meanings of their cultures and of traditional therapies. It is difficult and misguided to pose a diagnosis according to the criteria of Western psychiatry. Western psychiatry has been proven incompetent in its attempts to treat members of traditional societies, whether immigrants or in their countries of origin. And attempts to integrate traditional healing into a western medical system have not been successful. Traditional systems accomplish therapeutic goals by three major techniques, possession, shamanism, and clairvoyance, or their numerous variants. It is recommended that group sessions be held with immigrants requiring treatment, in which the principal therapist is assisted by translators, who help create a space for the patient intermediate between the two cultures, where the therapies can coexist without conflict.
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Energy Technology Data Exchange (ETDEWEB)
Stahlschmidt, S.; Hinze, S.
2016-07-01
Many developed countries have found their bibliometric impact measures to be improving over the last decade. Also the BRICS states, the economically largest group of developing countries, observe a similar pattern. This uniform growth seems puzzling, as not every country can improve its relative performance to all other countries. A possible explanation for this uniform growth might be found in the dynamic environment and especially in the exponential growth of Chinese publications. We like to analyze how this unprecedented growth of contributions from a single country with its specific bibliometric characteristics affects the whole bibliometric measurement process. We show that due to the lowly cited Chinese publications the overall corpus of scientific publications grows especially in the lower tail and argue that this unequal increase in publications benefits especially the bibliometric impact measures of developed countries. The actual magnitude of this effect will be derived by contrasting the actual bibliometric world with a counterfactual one without China. (Author)
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Costs of vaccine programs across 94 low- and middle-income countries.
Portnoy, Allison; Ozawa, Sachiko; Grewal, Simrun; Norman, Bryan A; Rajgopal, Jayant; Gorham, Katrin M; Haidari, Leila A; Brown, Shawn T; Lee, Bruce Y
2015-05-07
While new mechanisms such as advance market commitments and co-financing policies of the GAVI Alliance are allowing low- and middle-income countries to gain access to vaccines faster than ever, understanding the full scope of vaccine program costs is essential to ensure adequate resource mobilization. This costing analysis examines the vaccine costs, supply chain costs, and service delivery costs of immunization programs for routine immunization and for supplemental immunization activities (SIAs) for vaccines related to 18 antigens in 94 countries across the decade, 2011-2020. Vaccine costs were calculated using GAVI price forecasts for GAVI-eligible countries, and assumptions from the PAHO Revolving Fund and UNICEF for middle-income countries not supported by the GAVI Alliance. Vaccine introductions and coverage levels were projected primarily based on GAVI's Adjusted Demand Forecast. Supply chain costs including costs of transportation, storage, and labor were estimated by developing a mechanistic model using data generated by the HERMES discrete event simulation models. Service delivery costs were abstracted from comprehensive multi-year plans for the majority of GAVI-eligible countries and regression analysis was conducted to extrapolate costs to additional countries. The analysis shows that the delivery of the full vaccination program across 94 countries would cost a total of $62 billion (95% uncertainty range: $43-$87 billion) over the decade, including $51 billion ($34-$73 billion) for routine immunization and $11 billion ($7-$17 billion) for SIAs. More than half of these costs stem from service delivery at $34 billion ($21-$51 billion)-with an additional $24 billion ($13-$41 billion) in vaccine costs and $4 billion ($3-$5 billion) in supply chain costs. The findings present the global costs to attain the goals envisioned during the Decade of Vaccines to prevent millions of deaths by 2020 through more equitable access to existing vaccines for people in all
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Child Development in Developing Countries: Introduction and Methods
Bornstein, Marc H.; Britto, Pia Rebello; Nonoyama-Tarumi, Yuko; Ota, Yumiko; Petrovic, Oliver; Putnick, Diane L.
2012-01-01
The Multiple Indicator Cluster Survey (MICS) is a nationally representative, internationally comparable household survey implemented to examine protective and risk factors of child development in developing countries around the world. This introduction describes the conceptual framework, nature of the MICS3, and general analytic plan of articles…
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Strengthening health system to improve immunization for migrants in China.
Fang, Hai; Yang, Li; Zhang, Huyang; Li, Chenyang; Wen, Liankui; Sun, Li; Hanson, Kara; Meng, Qingyue
2017-07-01
Immunization is the most cost-effective method to prevent and control vaccine-preventable diseases. Migrant population in China has been rising rapidly, and their immunization status is poor. China has tried various strategies to strengthen its health system, which has significantly improved immunization for migrants. This study applied a qualitative retrospective review method aiming to collect, analyze and synthesize health system strengthening experiences and practices about improving immunizations for migrants in China. A conceptual framework of Theory of Change was used to extract the searched literatures. 11 searched literatures and 4 national laws and policies related to immunizations for migrant children were carefully studied. China mainly employed 3 health system strengthening strategies to significantly improve immunization for migrant population: stop charging immunization fees or immunization insurance, manage immunization certificates well, and pay extra attentions on immunization for special children including migrant children. These health system strengthening strategies were very effective, and searched literatures show that up-to-date and age-appropriate immunization rates were significantly improved for migrant children. Economic development led to higher migrant population in China, but immunization for migrants, particularly migrant children, were poor. Fortunately various health system strengthening strategies were employed to improve immunization for migrants in China and they were rather successful. The experiences and lessons of immunization for migrant population in China might be helpful for other developing countries with a large number of migrant population.
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The development of equine immunity: Current knowledge on immunology in the young horse.
Perkins, G A; Wagner, B
2015-05-01
The development of equine immunity from the fetus to adulthood is complex. The foal's immune response and the immune mechanisms that they are equipped with, along with changes over the first months of life until the immune system becomes adult-like, are only partially understood. While several innate immune responses seem to be fully functional from birth, the onset of adaptive immune response is delayed. For some adaptive immune parameters, such as immunoglobin (Ig)G1, IgG3, IgG5 and IgA antibodies, the immune response starts before or at birth and matures within 3 months of life. Other antibody responses, such as IgG4, IgG7 and IgE production, slowly develop within the first year of life until they reach adult levels. Similar differences have been observed for adaptive T cell responses. Interferon-gamma (IFN-γ) production by T helper 1 (Th1)-cells and cytotoxic T cells starts shortly after birth with low level production that gradually increases during the first year of life. In contrast, interleukin-4 (IL-4) produced by Th2-cells is almost undetectable in the first 3 months of life. These findings offer some explanation for the increased susceptibility of foals to certain pathogens such as Rhodococcus equi. The delay in Th-cell development and in particular Th2 immunity during the first months of life also provides an explanation for the reduced responsiveness of young horses to most traditional vaccines. In summary, all immune components of adult horses seem to exist in foals but the orchestrating and regulation of the immune response in immature horses is strikingly different. Young foals are fully competent and can perform certain immune responses but many mechanisms have yet to mature. Additional work is needed to improve our understanding of immunity and immune regulation in young horses, to identify the preferred immune pathways that they are using and ultimately provide new preventive strategies to protect against infectious disease. © 2015 EVJ Ltd.
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[The informed consent in international clinical trials including developing countries].
Montenegro Surís, Alexander; Monreal Agüero, Magda Elaine
2008-01-01
The informed consent procedure has been one of the most important controversies of ethical debates about clinical trials in developing countries. In this essay we present our recommendations about important aspects to consider in the informed consent procedure for clinical trials in developing countries. We performed a full publications review identified by MEDLINE using these terms combinations: informed consent, developing countries, less developed countries and clinical trials. To protect volunteers in less developed countries should be valuated the importance of the community in the informed consent proceeding. The signing and dating of the informed consent form is not always the best procedure to document the informed consent. The informed consent form should be written by local translators. Alternative medias of communications could be needed for communicatios of the information to volunteers. Comparing with developed countries the informed consent proceeding in clinical trials in developing countries frequently require additional efforts. The developing of pragmatic researches is needed to implement informed consent proceedings assuring subjects voluntarily in each developing country. The main aspects to define in each clinical trial for each country are the influence of the community, the effective communication of the information, the documentation of the informed consent and local authority's control.
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Management of Radioactive Wastes in Developing Countries
International Nuclear Information System (INIS)
Abdel Ghani, A.H.
1999-01-01
The management of radioactive wastes is one area of increasing interest especially in developing countries having more and more activities in the application of radioisotopes in medicine, research and industry. For a better understanding of radioactive waste management in developing countries this work will discuss the following items:Classification of countries with respect to waste management programs. Principal Radionuclides used in medicine, biological research and others and the range of radioactivity commonly used. Estimation of radioactive waste volumes and activities. Management of liquid wastes Collection. Treatment. Management of small volumes of organic liquid waste. Collection Treatment. Packaging and storage of radioactive wastes
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Causal Attributions for Poverty in Developing Countries
Directory of Open Access Journals (Sweden)
José Juan Vázquez
2009-07-01
Full Text Available This paper analyzes attributional differences about causes of poverty in the less developed countries, among Nicaraguan ("actors" and Spanish ("observers" undergraduates. A self–applied questionnaire was used. It included socio–demographic questions and an adaptation of the "Causes of Third World Poverty Questionnaire" (CTWPQ. Results show agreement between Spanish and Nicaraguan in attributions about the main causes of poverty in the less developed countries, although there are differences about the perception of the incidence of the different causes in that situation. Nicaraguan students consider, as causes of poverty, more dispositional attributes about the population in those countries.
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Teacher labor markets in developed countries.
Ladd, Helen F
2007-01-01
Helen Ladd takes a comparative look at policies that the world's industrialized countries are using to assure a supply of high-quality teachers. Her survey puts U.S. educational policies and practices into international perspective. Ladd begins by examining teacher salaries-an obvious, but costly, policy tool. She finds, perhaps surprisingly, that students in countries with high teacher salaries do not in general perform better on international tests than those in countries with lower salaries. Ladd does find, however, that the share of underqualified teachers in a country is closely related to salary. In high-salary countries like Germany, Japan, and Korea, for example, only 4 percent of teachers are underqualified, as against more than 10 percent in the United States, where teacher salaries, Ladd notes, are low relative to those in other industrialized countries. Teacher shortages also appear to stem from policies that make salaries uniform across academic subject areas and across geographic regions. Shortages are especially common in math and science, in large cities, and in rural areas. Among the policy strategies proposed to deal with such shortages is to pay teachers different salaries according to their subject area. Many countries are also experimenting with financial incentive packages, including bonuses and loans, for teachers in specific subjects or geographic areas. Ladd notes that many developed countries are trying to attract teachers by providing alternative routes into teaching, often through special programs in traditional teacher training institutions and through adult education or distance learning programs. To reduce attrition among new teachers, many developed countries have also been using formal induction or mentoring programs as a way to improve new teachers' chances of success. Ladd highlights the need to look beyond a single policy, such as higher salaries, in favor of broad packages that address teacher preparation and certification
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Policy alternatives in reforming energy utilities in developing countries
International Nuclear Information System (INIS)
Gabriele, Alberto
2004-01-01
This paper examines the policy alternatives faced by developing countries in their endeavor to preserve and develop their electricity and gas systems, two service-oriented industries which--along with oil--provide the bulk of energy supply both in developed and in developing countries. Even in very poor countries, industrially generated energy is indispensable for carrying out most economic activities. Therefore, governments traditionally recognize that the supply of gas and electricity entails a fundamental public service dimension. The Introduction presents the case for reforming of energy utilities, discusses in general terms the pros and cons of privatization, and attempts to locate the reforms in a broader historical framework in which developing countries' governments faced characterized by increasing financial hardship. Section 2 constitutes the core of the paper. It reviews the main features of gas and power sector reforms in the developing world and analyzes specifically the cases of five semi-industrialized countries in Latin America and Asia. Section 3 (Concluding remarks) briefly evaluates the country experiences reviewed above and indicates a few policy lessons which can be learnt from them. The main conclusion is that, in a long-run development perspective, full-scale privatization of gas and power sectors in developing countries entails significant risks, and therefore a flexible policy approach is preferable to a rigid commitment to extensive liberalization
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[The role of immune system in the control of cancer development and growth].
Sütő, Gábor
2016-06-01
The role of immune system is the maintenace of the integritiy of the living organism. The elements of the immune system are connected by several ways forming a complex biological network. This network senses the changes of the inner and outer environment and works out the most effective response against infections and tumors. Dysfunction of the immune system leads to the development of cancer development and chronic inflammatory diseases. Modulation of the checkpoints of the immune system opened new perspecitves in the treatment of rheumatological and oncological diseases as well. Beside the potent antiinflammatory activity, new therapies are able to stimulate anticancer activity of the immune system. The result of these recent developments is a better outcome of malignant diseases, which had an unfavorable outcome in the past. Orv. Hetil., 2016, 157(Suppl. 2), 3-8.
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Ruwan Jayasuriya
2008-01-01
Globalization defined as falling barriers to, and the increase in, trade, migration, and investment across borders directly affects workers in both developed and developing countries. While most global trade and investment is between the developed countries, globalization has increased dramatically in a number of developing countries. Understanding the effects of globalization is critical ...
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Obesity and the metabolic syndrome in developing countries.
Misra, Anoop; Khurana, Lokesh
2008-11-01
Prevalence of obesity and the metabolic syndrome is rapidly increasing in developing countries, leading to increased morbidity and mortality due to type 2 diabetes mellitus (T2DM) and cardiovascular disease. Literature search was carried out using the terms obesity, insulin resistance, the metabolic syndrome, diabetes, dyslipidemia, nutrition, physical activity, and developing countries, from PubMed from 1966 to June 2008 and from web sites and published documents of the World Health Organization and Food and Agricultural Organization. With improvement in economic situation in developing countries, increasing prevalence of obesity and the metabolic syndrome is seen in adults and particularly in children. The main causes are increasing urbanization, nutrition transition, and reduced physical activity. Furthermore, aggressive community nutrition intervention programs for undernourished children may increase obesity. Some evidence suggests that widely prevalent perinatal undernutrition and childhood catch-up obesity may play a role in adult-onset metabolic syndrome and T2DM. The economic cost of obesity and related diseases in developing countries, having meager health budgets is enormous. To prevent increasing morbidity and mortality due to obesity-related T2DM and cardiovascular disease in developing countries, there is an urgent need to initiate large-scale community intervention programs focusing on increased physical activity and healthier food options, particularly for children. International health agencies and respective government should intensively focus on primordial and primary prevention programs for obesity and the metabolic syndrome in developing countries.
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Duclos, Philippe; Okwo-Bele, Jean-Marie; Salisbury, David
2011-02-01
The vaccine landscape has changed considerably over the last decade with many new vaccines and technological developments, unprecedented progress in reaching out to children and the development of new financing mechanisms. At the same time, there are more demands and additional expectations of national policy makers, donors and other interested parties for increased protection through immunization. The Global Immunization Vision and Strategy (GIVS), which broadens the previous scope of immunization efforts, sets a number of goals to be met by countries. The WHO has recently reviewed and adjusted both its policy making structure and processes for vaccines and immunization to include an enlarged consultation process to generate evidence-based recommendations, thereby ensuring the transparency of the decision making process and improving communications. This article describes the process of development of immunization policy recommendations at the global level and some of their impacts. It focuses on the roles and modes of operating of the Strategic Advisory Group of Experts on immunization, which is the overarching advisory group involved with the issuance of policy recommendations, monitoring and facilitating the achievement of the GIVS goals. The article also describes the process leading to the publication of WHO vaccine position papers, which provide WHO recommendations on vaccine use. WHO vaccine-related recommendations have become a necessary step in the pathway to the introduction and use of vaccines, especially in developing countries and, consequently, have a clear and significant impact.
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Palliative radiotherapy in developing countries
International Nuclear Information System (INIS)
Allen, B.J.
2010-01-01
Full text: The International Agency for Research on Cancer predicts that cancer incidence in developing countries will increase dramatically in the first two decades of this millennium. Already some 80% of cancer patients in developing countries present with incurable disease. [n many cases pain is a severe problem and palliation is needed to improve quality of life as well as extending survival. This paper will consider the physical and clinical aspects of palliative radiotherapy (PRT), choice of radiation modality, alternative approaches to imaging and therapy and cost-benefit considerations. The potential benefits of a dedicated palliative centre include lower cost and therefore more centres, enabling more patients access to regional palliative care. Whilst there is an obvious need for palliative radiotherapy, simple curative treatments could also be managed. C060 radiotherapy has important advantages in developing countries, because of the higher initial cost of a linear accelerator, as well as the need for reliable power supply and the level of skill required by linac technicians and physicists. The beam characteristics of both C060 units and low energy linacs are compared and both are found to be acceptable for palliation. The concept of telemedicine is also discussed, using mobile phones and internet communication to allow rural clinics to receive support from specialists based in the cities, to send images for remote diagnosis and remote dose planning for radiotherapy. (author)
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Fahmy, Kamal; Hampton, Lee M; Langar, Houda; Patel, Manish; Mir, Tahir; Soloman, Chandrasegarar; Hasman, Andreas; Yusuf, Nasir; Teleb, Nadia
2017-07-01
The Global Polio Eradication Initiative has reduced the global incidence of polio by 99% and the number of countries with endemic polio from 125 to 3 countries. The Polio Eradication and Endgame Strategic Plan 2013-2018 (Endgame Plan) was developed to end polio disease. Key elements of the endgame plan include strengthening immunization systems using polio assets, introducing inactivated polio vaccine (IPV), and replacing trivalent oral polio vaccine with bivalent oral polio vaccine ("the switch"). Although coverage in the Eastern Mediterranean Region (EMR) with the third dose of a vaccine containing diphtheria, tetanus, and pertussis antigens (DTP3) was ≥90% in 14 countries in 2015, DTP3 coverage in EMR dropped from 86% in 2010 to 80% in 2015 due to civil disorder in multiple countries. To strengthen their immunization systems, Pakistan, Afghanistan, and Somalia developed draft plans to integrate Polio Eradication Initiative assets, staff, structure, and activities with their Expanded Programmes on Immunization, particularly in high-risk districts and regions. Between 2014 and 2016, 11 EMR countries introduced IPV in their routine immunization program, including all of the countries at highest risk for polio transmission (Afghanistan, Pakistan, Somalia, and Yemen). As a result, by the end of 2016 all EMR countries were using IPV except Egypt, where introduction of IPV was delayed by a global shortage. The switch was successfully implemented in EMR due to the motivation, engagement, and cooperation of immunization staff and decision makers across all national levels. Moreover, the switch succeeded because of the ability of even the immunization systems operating under hardship conditions of conflict to absorb the switch activities. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America.
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Mitchell, James M.; Luikart, F. W.
The feasibility of creating independent research and education centers that deal with public policy issues in developing countries is assessed. Countries that were surveyed include Brazil, Colombia, Bolivia, Costa Rica, Guatemala, South Korea, Philippines, Pakistan, and Nepal. For each country, a report describes the social and political climate…
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Applying Mathematical Tools to Accelerate Vaccine Development: Modeling Shigella Immune Dynamics
Davis, Courtney L.; Wahid, Rezwanul; Toapanta, Franklin R.; Simon, Jakub K.
2013-01-01
We establish a mathematical framework for studying immune interactions with Shigella, a bacteria that kills over one million people worldwide every year. The long-term goal of this novel approach is to inform Shigella vaccine design by elucidating which immune components and bacterial targets are crucial for establishing Shigella immunity. Our delay differential equation model focuses on antibody and B cell responses directed against antigens like lipopolysaccharide in Shigella’s outer membrane. We find that antibody-based vaccines targeting only surface antigens cannot elicit sufficient immunity for protection. Additional boosting prior to infection would require a four-orders-of-magnitude increase in antibodies to sufficiently prevent epithelial invasion. However, boosting anti-LPS B memory can confer protection, which suggests these cells may correlate with immunity. We see that IgA antibodies are slightly more effective per molecule than IgG, but more total IgA is required due to spatial functionality. An extension of the model reveals that targeting both LPS and epithelial entry proteins is a promising avenue to advance vaccine development. This paper underscores the importance of multifaceted immune targeting in creating an effective Shigella vaccine. It introduces mathematical models to the Shigella vaccine development effort and lays a foundation for joint theoretical/experimental/clinical approaches to Shigella vaccine design. PMID:23589755
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Renewable energy education in developing countries
International Nuclear Information System (INIS)
Bara, M.F.
2006-01-01
The global call for more and more penetration of renewable energy sources in the energy mix for several countries driven by various different motives including the desire for attaining sustainable development through the use of these renewable sources, for decreasing pollution, trying to decrease dependency on imported fuels or to exploit the locally available renewable resources, this call has not been satisfactorily responded to, partially, it is believed here, due to the lack of awareness and adequate manpower qualifications in these sources at the different levels of decision making. Energy education in many countries is still not so dynamic to coup with the ever changing circumstances and developments related to the demand, supply, technologies, economics policies as well as environmental aspects this is more noticed in the world developing countries, with other related obstacles facing the desired and needed wider application of renewable energy sources. The paper will try to handle this situation, analyzing its components, citing some examples of good fruitful practice in this connection, and drawing some recommendations that may help in improving the same
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Energy Issues and Problems in Developing Countries
International Nuclear Information System (INIS)
Mehdizadeh, Saeed
1999-01-01
In general, the developing countries due to changes in supply and demand for energy in the world, are facing several problems, such as: 1. Energy growth. 2.Energy consumption 3.Environmental protection. The objective of this paper is to study the problems caused by the increase in the energy consumption of the developing countries. also several guideline and solution schemes are recommended for these problems
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Increasing transparency in the European Union: developments of Country-by-Country Reporting
Directory of Open Access Journals (Sweden)
Alicja Brodzka
2017-09-01
Full Text Available Increasing transparency in the European Union: developments of Country-by-Country Reporting The aim of the paper is to bring closer Country-by-Country Reporting and outline possible future amendments of the introduced anti-tax avoidance measures. The article presents the motives of implementing the international CbC initiative, aimed at increasing transparency of the biggest multinational enterprises, with particular emphasis on the specificity of the European Union. Part 2 of the paper analyses the Euro-pean legal bases for companies’ financial reporting. It also gives an overview of the main findings of Directive 2016/881, which implements Country-by-Country Reporting and allows for the exchange of information between tax authorities. Part 3 deals with the national perspective, presenting the CbC solu-tions implemented to the Polish legal system; the paper also attempts to assess the potential impact of tax information disclosures, both from the perspective of taxpayers and the tax administration. The final part presents conclusions and tries to draft future developments of the Country-by-Country Reporting system. In the paper, the following research methods have been used: critical analysis and deduction, with partic-ular reference to the source materials and legal acts, as well as the reports of the European Commission, consulting companies, and NGOs. Although the article deals with tax matters, CbC Reporting is an im-portant and relevant issue from the point of view of researchers and accounting specialists. Reporting this phenomenon is part of the accounting science as a universal tool for recording economic phenomena. The author examined all relevant sources and took into account all important factors in order to obtain a com-prehensive picture of CbC Reporting and to prepare a paper that may serve as a reference for future research.
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Capital goods for energy development: power equipment for developing countries
International Nuclear Information System (INIS)
Parikh, J.K.
1986-01-01
Questions of energy policy in developing countries are considered, with the goal of 'evolution from exports to indigenization' i.e. independence. Levels of technologies are considered in relation to the resources of each country. Nuclear power is considered among other energy sources. (G.Q.)
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Chee, Chiu Mei; Butt, Muhammad Mohsin; Wilkins, Stephen; Ong, Fon Sim
2016-01-01
Over the last decade, international branch campuses have been established by universities from developing countries as well as developed countries. Little research has been conducted into students' perceptions of branch campuses from different countries, or how universities from different countries compete in the increasingly competitive market. A…
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Domestic biogas development in developing countries
International Nuclear Information System (INIS)
Rakotojaona, Loic
2013-07-01
Communities that rely mostly on agriculture and livestock farming in developing countries can face strong pressure related to: - Energy access: for instance, in Africa, it is estimated that 68% of the population live without clean cooking facilities [1]. Energy access plays a key role in poverty alleviation. - Resources depletion: if a household uses firewood for cooking purposes, forests depletion in some areas makes firewood collection tougher. - Climate change mitigation: agriculture (i.e. the production of crop and livestock products) accounts for 13.5%2 of the global GHG emissions, and extensive systems are sometimes blamed for being less efficient than intensive ones when it comes to climate change mitigation (given that the later involve lower direct emissions per kg of product). In this context, access to clean and sustainable energy through domestic biogas production can help rural communities alleviate current pressures on the environment. In an urban context, domestic biogas in developing countries is also considered as a means for improving hygiene conditions (especially when it comes to public washrooms issues). This report only focuses on domestic biogas development within the frame of small scale agriculture and livestock production (i.e. in rural areas). The main objective of this document is to provide domestic biogas project developers with relevant information on the key issues to have in mind regarding national integration of such projects. This document gives a general presentation of domestic biogas and its main environmental, social and economic benefits. It also browses the main aspects one should have in mind (checklist) in order to assess local risks and opportunities for domestic biogas development
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IMF and economic reform in developing countries
DEFF Research Database (Denmark)
Abbott, Philip; Andersen, Thomas Barnebeck; Tarp, Finn
2010-01-01
approach is in order. However, the cross-country approach is unlikely to provide a sound basis for drawing clear conclusions, so we review IMF programs from a different perspective, involving a broader literature on development strategy. In particular, it is widely accepted that a common characteristic......In this paper we assess the IMF approach to economic reform in developing countries. The impact of IMF program participation on economic growth has been evaluated empirically in a cross-country literature, with little evidence of IMF programs having been successful. This suggests that a fresh...... of IMF programs is a high degree of policy rigidity. This is in contrast with studies which hold that unleashing an economy's growth potential hinges on a set of well-targeted policy interventions aimed at removing country-specific binding constraints. The process of locating constraints that bind...
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Blayney, K D; Trulove, J W
1982-10-01
Allied health manpower in developing countries should be able to serve the specific needs of these countries in solving malnutrition, diarrheal disease, and other health problems. Disease patterns tend to evolve in stages with each stage requiring a special type of health manpower: 1) the 1st stage where infectious diseases are linked to poverty, malnutrition, and poor personal hygiene for which personnel trained to improve health through providing safe water supplies, improving sanitation, and immunizing the population are needed; 2) in the 2nd stages, diseases such as cancer, arthritis, and cardiac diseases exist, requiring extensive technology such as is available in the US; and 3) the 3rd stage relates to an awareness of health hazards (caused by the environment, by the lifestyle dysfunctions of the society, and an emphasis on health promotion) and implies a responsibility for one's own health by the individual; this is a difficult stage to apply to developing countries since the ability to bring about change assumes literacy on the part of the population which is not always the case. Since most developing countries need to cause change in the 1st stage, more public health personnel such as sanitarians and generalist workers are needed. Training of these personnel should include on-the-job education; traditionally trained US allied health professionals are not always equipped to deal with health problems in developing countries. Health educators should look to the lessons learned by the US in the allied health movement: 1) the system of control that national membership organizations have over schooling and the job environment has contributed to an increased cost of health care delivery, unnecessary prolonged curricula, overspecialization, extreme protectionism for membership, and inappropriate fractionalization of health care delivery; 2) the emphasis on prolonged curricula sometimes causes the student to lose sight of the supposed direct relationship between
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Directory of Open Access Journals (Sweden)
Bruno F Sunguya
Full Text Available BACKGROUND: Evidence is available on the potential efficacy of interprofessional education (IPE to foster interprofessional cooperation, improve professional satisfaction, and improve patient care. While the intention of the World Health Organization (WHO is to implement IPE in all countries, evidence comes from developed countries about its efficiency, challenges, and barriers to planning and implementing IPE. We therefore conducted this review to examine challenges of implementing IPE to suggest possible pathways to overcome the anticipated challenges in developing countries. METHODS: We searched for literatures on IPE in PubMed/MEDLINE, CINAHL, PsycINFO, and ERIC databases. We examined challenges or barriers and initiatives to overcome them so as to suggest methods to solve the anticipated challenges in developing countries. We could not conduct a meta-analysis because of the qualitative nature of the research question and the data; instead we conducted a meta-narrative of evidence. RESULTS: A total of 40 out of 2,146 articles were eligible for analyses in the current review. Only two articles were available from developing countries. Despite the known benefits of IPE, a total of ten challenges or barriers were common based on the retrieved evidence. They included curriculum, leadership, resources, stereotypes and attitudes, variety of students, IPE concept, teaching, enthusiasm, professional jargons, and accreditation. Out of ten, three had already been reported in developing countries: IPE curriculum, resource limitations, and stereotypes. CONCLUSION: This study found ten important challenges on implementing IPE. They are curriculum, leadership, resources, stereotypes, students' diversity, IPE concept, teaching, enthusiasm, professional jargons, and accreditation. Although only three of them are already experienced in developing countries, the remaining seven are potentially important for developing countries, too. By knowing these
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Sunguya, Bruno F; Hinthong, Woranich; Jimba, Masamine; Yasuoka, Junko
2014-01-01
Evidence is available on the potential efficacy of interprofessional education (IPE) to foster interprofessional cooperation, improve professional satisfaction, and improve patient care. While the intention of the World Health Organization (WHO) is to implement IPE in all countries, evidence comes from developed countries about its efficiency, challenges, and barriers to planning and implementing IPE. We therefore conducted this review to examine challenges of implementing IPE to suggest possible pathways to overcome the anticipated challenges in developing countries. We searched for literatures on IPE in PubMed/MEDLINE, CINAHL, PsycINFO, and ERIC databases. We examined challenges or barriers and initiatives to overcome them so as to suggest methods to solve the anticipated challenges in developing countries. We could not conduct a meta-analysis because of the qualitative nature of the research question and the data; instead we conducted a meta-narrative of evidence. A total of 40 out of 2,146 articles were eligible for analyses in the current review. Only two articles were available from developing countries. Despite the known benefits of IPE, a total of ten challenges or barriers were common based on the retrieved evidence. They included curriculum, leadership, resources, stereotypes and attitudes, variety of students, IPE concept, teaching, enthusiasm, professional jargons, and accreditation. Out of ten, three had already been reported in developing countries: IPE curriculum, resource limitations, and stereotypes. This study found ten important challenges on implementing IPE. They are curriculum, leadership, resources, stereotypes, students' diversity, IPE concept, teaching, enthusiasm, professional jargons, and accreditation. Although only three of them are already experienced in developing countries, the remaining seven are potentially important for developing countries, too. By knowing these challenges and barriers in advance, those who implement IPE programs
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Management of radioactive wastes in developing countries: Growing needs
International Nuclear Information System (INIS)
Thomas, K.T.
1992-01-01
Wide variations in the development and use of nuclear energy are evident in developing countries. A few have or are pursuing partial or complete nuclear fuel cycle activities. Eleven developing countries have nuclear power plants with a total installed capacity of 8600 megawatts-electric (MWe). Because of the increasing demand for electrical energy, more developing countries would like to have nuclear power. But most of them are constrained by lack of finances and technical expertise. Some have research reactors, and a few have uranium mining and milling operations. Most developing countries are using nuclear energy for applications in fields of medicine, agriculture, industry, and research. From all these uses, radioactive waste is produced that must be managed safely and efficiently. Increasingly in recent years, countries have turned to the IAEA for technical assistance and waste management services to address serious problems they are facing. 1 map
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Nuclear power programmes in developing countries
International Nuclear Information System (INIS)
Anon.
1988-01-01
The paper on ''Nuclear power programmes in developing countries'' is a report to the IAEA by a Senior Expert Group. A description is given of the requirements for a successful nuclear power programme, including the constraints that developing countries might face in the introduction and execution of the programme. The group attempted to identify the main issues affecting the financing of nuclear power projects and suggested specific actions that could be undertaken in order to reduce economic and financial risks. The various issues were discussed under the topic headings:-programme-project-related factors, investment climate, financing plan, export credits and creditworthiness. (U.K.)
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Combating infection in developing countries. The IAEA contribution
International Nuclear Information System (INIS)
Groth, Stefan; Khan, Baldip; Padhy, Ajit; Soo Ling Ch'ng; Soricelli, Andreas; Yanfen Xie; Ford, JoAnne
2000-08-01
Control of infection and infectious diseases is an international priority. Worldwide infectious diseases are responsible for an estimated 13 million deaths each year, exacting a large and disproportionately high toll in developing countries. Forty-three percent of all deaths in developing countries are due to infectious diseases, whereas the corresponding figure for developed countries is only 1%. A large proportion of these deaths could be prevented if timely diagnosis and effective treatment were available locally. Loss of life or productivity due to infectious disease is not just a health matter, it also has an important social and economic impact on individuals, families, regions, and countries. According to the World Health Organization, infectious diseases are now the world's largest killer of young adults and children. Hundreds of millions of people are disabled by infectious disease. The economic impact of repeated episodes of illness and long term disability is a major cause of underdevelopment in many countries today. For example, according to the WHO 1999 Infectious Disease Report, malaria alone has cost Africa billions of dollars in the past decade. More recently, a WHO study estimates that malaria slows economic growth in Africa by up to 1.3% each year and that malaria-free countries average three times higher gross domestic product per person than do malarious countries. This brochure highlights the role of the International Atomic Energy Agency (IAEA) in disseminating nuclear techniques to combat infection and infectious disease. Some of the techniques are used to diagnose and manage infectious diseases of serious concern to developing countries - malaria, tuberculosis, hepatitis, and Chagas disease. Other techniques are used to detect infection sites in the body, in bones, and organs. The challenges posed by infection and infectious disease and the nuclear techniques that the Agency offers for support illustrate how nuclear techniques can be used to
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Combating infection in developing countries. The IAEA contribution
Energy Technology Data Exchange (ETDEWEB)
Groth, Stefan [International Atomic Energy Agency, Vienna (Austria). Division of Human Health; Khan, Baldip; Padhy, Ajit; Ch' ng, Soo Ling; Soricelli, Andreas; Xie, Yanfen [International Atomic Energy Agency, Vienna (Austria). Division of Human Health, Nuclear Medicine Section; Ford, JoAnne [International Atomic Energy Agency, Vienna (Austria). Division of Public Information
2000-08-01
Control of infection and infectious diseases is an international priority. Worldwide infectious diseases are responsible for an estimated 13 million deaths each year, exacting a large and disproportionately high toll in developing countries. Forty-three percent of all deaths in developing countries are due to infectious diseases, whereas the corresponding figure for developed countries is only 1%. A large proportion of these deaths could be prevented if timely diagnosis and effective treatment were available locally. Loss of life or productivity due to infectious disease is not just a health matter, it also has an important social and economic impact on individuals, families, regions, and countries. According to the World Health Organization, infectious diseases are now the world's largest killer of young adults and children. Hundreds of millions of people are disabled by infectious disease. The economic impact of repeated episodes of illness and long term disability is a major cause of underdevelopment in many countries today. For example, according to the WHO 1999 Infectious Disease Report, malaria alone has cost Africa billions of dollars in the past decade. More recently, a WHO study estimates that malaria slows economic growth in Africa by up to 1.3% each year and that malaria-free countries average three times higher gross domestic product per person than do malarious countries. This brochure highlights the role of the International Atomic Energy Agency (IAEA) in disseminating nuclear techniques to combat infection and infectious disease. Some of the techniques are used to diagnose and manage infectious diseases of serious concern to developing countries - malaria, tuberculosis, hepatitis, and Chagas disease. Other techniques are used to detect infection sites in the body, in bones, and organs. The challenges posed by infection and infectious disease and the nuclear techniques that the Agency offers for support illustrate how nuclear techniques can be used to
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Energy Technology Data Exchange (ETDEWEB)
Nashashibi, H S
1980-10-01
Private transfers of capital from the Organization of Petroleum Exporting Countries (OPEC) to developing countries are intended to complement private transfers from the Organization of Economic Cooperation and Development (OECD) by tapping the emerging capital markets in the Middle East. Developing countries will be able to diversify their borrowing and gain additional financing. The long-term investment of oil-producing countries will benefit and the pressures on the banking institutions to recycle funds will lessen. Middle East capital markets include international loans and international bonds. The history of the Kuwaiti dinar (KD) bond market, with its advantages for both investors and borrowers, illustrates the successful development of a capital market. Financial intermediation needs to be improved, however, if the Middle East is to become efficient enough to compete with the Euromarkets. Efficiency will require different measures and should reflect strengthening relationships among Middle East nations. (DCK)
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Bureau Management Technologies and Information Systems in Developing Countries
Mehmet Altınöz
2008-01-01
This study focuses on bureau management technologies and information systems in developing countries. Developing countries use such systems which facilitate executive and organizational functions through the utilization of bureau management technologies and provide the executive staff with necessary information. The concepts of data and information differ from each other in developing countries, and thus the concepts of data processing and information processing are di...
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Causal Attributions for Poverty in Developing Countries
José Juan Vázquez; Sonia Panadero
2009-01-01
This paper analyzes attributional differences about causes of poverty in the less developed countries, among Nicaraguan ("actors") and Spanish ("observers") undergraduates. A self–applied questionnaire was used. It included socio–demographic questions and an adaptation of the "Causes of Third World Poverty Questionnaire" (CTWPQ). Results show agreement between Spanish and Nicaraguan in attributions about the main causes of poverty in the less developed countries, although there are difference...
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Climate volatility deepens poverty vulnerability in developing countries
Ahmed, Syud A.; Diffenbaugh, Noah S.; Hertel, Thomas W.
2009-07-01
Extreme climate events could influence poverty by affecting agricultural productivity and raising prices of staple foods that are important to poor households in developing countries. With the frequency and intensity of extreme climate events predicted to change in the future, informed policy design and analysis requires an understanding of which countries and groups are going to be most vulnerable to increasing poverty. Using a novel economic-climate analysis framework, we assess the poverty impacts of climate volatility for seven socio-economic groups in 16 developing countries. We find that extremes under present climate volatility increase poverty across our developing country sample—particularly in Bangladesh, Mexico, Indonesia, and Africa—with urban wage earners the most vulnerable group. We also find that global warming exacerbates poverty vulnerability in many nations.
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Climate volatility deepens poverty vulnerability in developing countries
International Nuclear Information System (INIS)
Ahmed, Syud A; Diffenbaugh, Noah S; Hertel, Thomas W
2009-01-01
Extreme climate events could influence poverty by affecting agricultural productivity and raising prices of staple foods that are important to poor households in developing countries. With the frequency and intensity of extreme climate events predicted to change in the future, informed policy design and analysis requires an understanding of which countries and groups are going to be most vulnerable to increasing poverty. Using a novel economic-climate analysis framework, we assess the poverty impacts of climate volatility for seven socio-economic groups in 16 developing countries. We find that extremes under present climate volatility increase poverty across our developing country sample-particularly in Bangladesh, Mexico, Indonesia, and Africa-with urban wage earners the most vulnerable group. We also find that global warming exacerbates poverty vulnerability in many nations.
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Helping transfer technology to developing countries
International Nuclear Information System (INIS)
Masters, R.
1978-01-01
Manpower planning and training are an increasingly important part of the activities of the IAEA which organises a number of courses for engineers and administrators from developing countries. The Agency supports the view of these countries that there should be a real transfer of nuclear technology and not just the import of equipment and services. A Construction and Operation Management course held at Karlsruhe, is reviewed. (author)
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Decentralisation in developing countries: preconditions for successful implementation
Directory of Open Access Journals (Sweden)
Yasin Olum
2014-07-01
Full Text Available Decentralisation has been implemented and is being implemented in many developing countries without much success. Although several unique factors inhibit the implementation of decentralisation in individual countries, the paper argues that there are six pre-conditions that these countries should fulfill before decentralisation can be successfully implemented. These preconditions are: institutional mechanisms; creation of spaces for participation; political will and civil will; capacity development at the local level; careful implementation; and democratic governance.
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social protection for developing countries
African Journals Online (AJOL)
Nicola Smit
challenges of informal economy workers in developing countries. This view. 5 ibid. ..... in the informal economy – an international and regional perspective” 2007 4 TSAR 700-715. ..... management – should be improved. In South Africa the ...
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Immunity and privilege of international organizations in Kosovo
Directory of Open Access Journals (Sweden)
Arif Riza
2016-11-01
Full Text Available To speak for the Diplomatic Law (Immunities and Privileges in International Organizations, first, this topic briefly describes the international organizations, what are they, as established, as extinct, and finally, as a shared international organizations. They are not subject of this paper, but Immunity and Privileges in International Organizations are. This paper gives an overview of the history of the immunity and privileges in international organizations, conventions, laws of the country regarding Immunities and Privileges, where the seat of the International Organization, Immunities and privileges of diplomatic representatives in international organizations, Immunities and privileges of representatives of international organizations in the state where the seat of the Organization, immunity and privileges of members of the family, diplomatic representatives International Organizations, Immunities and Privileges in the European Union, the difference between the immunity and privileges of international organizations, and Immunity and Privileges between states. This paper analyzes also the immunity and inviolability of buildings of International Organizations, immunity and inviolability of the archives of international organizations, the immunity and privileges of goods to international organizations, the release from the obligation of tax payments, the release from the provision of the diplomatic staff of International Organizations, etc. However, the paper includes charts, respectively, some official data from countries where the headquarters of international organizations are situated and gives an overview of the number of international governmental and nongovernmental organizations.
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The Immune System in Obesity: Developing Paradigms Amidst Inconvenient Truths.
Agrawal, Madhur; Kern, Philip A; Nikolajczyk, Barbara S
2017-08-15
Adipose tissue (AT) houses both innate and adaptive immune systems that are crucial for preserving AT function and metabolic homeostasis. In this review, we summarize recent information regarding progression of obesity-associated AT inflammation and insulin resistance. We additionally consider alterations in AT distribution and the immune system in males vs. females and among different racial populations. Innate and adaptive immune cell-derived inflammation drives insulin resistance both locally and systemically. However, new evidence also suggests that the immune system is equally vital for adipocyte differentiation and protection from ectopic lipid deposition. Furthermore, roles of anti-inflammatory immune cells such as regulatory T cells, "M2-like" macrophages, eosinophils, and mast cells are being explored, primarily due to promise of immunotherapeutic applications. Both immune responses and AT distribution are strongly influenced by factors like sex and race, which have been largely underappreciated in the field of metabolically-associated inflammation, or meta-flammation. More studies are required to recognize factors that switch inflammation from controlled to uncontrolled in obesity-associated pathogenesis and to integrate the combined effects of meta-flammation and immunometabolism. It is critical to recognize that the AT-associated immune system can be alternately beneficial and destructive; therefore, simply blocking immune responses early in obesity may not be the best clinical approach. The dearth of information on gender and race-associated disparities in metabolism, AT distribution, and the immune system suggest that a greater understanding of such differences will be critical to develop personalized treatments for obesity and the associated metabolic dysfunction.
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Solar passive buildings for developing countries
International Nuclear Information System (INIS)
Gupta, C.L.
1993-01-01
This paper is meant to be an indicative survey of developments in solar passive building technology relevant to developing countries. The evolution of this area during the last fifty years is reported along with the scientific principles and design concepts underlying these developments. Factors to be considered for design strategies such as direct gain, isolated gain, indirect gain and roof evaporative systems are then described. Rating parameters for assessing the performance and benefit and cost parameters are then outlined. Successful examples illustrating each of the design concepts, mainly from Indian buildings constructed during the last fifteen years, are then detailed along with their performance based on actual monitoring, if available. Concluding remarks indicate the current and future trends. A survey is made of papers marking significant milestones in the development of solar passive building technology relevant to developing countries. (author). 48 refs., 14 figs., 3 tabs
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Directory of Open Access Journals (Sweden)
Yun Huang
2016-07-01
Full Text Available Objective: Using estimates from the 2013 Global Burden of Disease (GBD study, we update evidence on disparities in under-five child injury mortality between developing and developed countries from 1990 to 2013. Methods: Mortality rates were accessed through the online visualization tool by the GBD study 2013 group. We calculated percent change in child injury mortality rates between 1990 and 2013. Data analysis was conducted separately for <1 year and 1–4 years to specify age differences in rate changes. Results: Between 1990 and 2013, over 3-fold mortality gaps were observed between developing countries and developed countries for both age groups in the study time period. Similar decreases in injury rates were observed for developed and developing countries (<1 year: −50% vs. −50% respectively; 1–4 years: −56% vs. −58%. Differences in injury mortality changes during 1990–2013 between developing and developed nations varied with injury cause. There were greater reductions in mortality from transport injury, falls, poisoning, adverse effects of medical treatment, exposure to forces of nature, and collective violence and legal intervention in developed countries, whereas there were larger decreases in mortality from drowning, exposure to mechanical forces, and animal contact in developing countries. Country-specific analysis showed large variations across countries for both injury mortality and changes in injury mortality between 1990 and 2013. Conclusions: Sustained higher child injury mortality during 1990–2013 for developing countries merits the attention of the global injury prevention community. Countries that have high injury mortality can benefit from the success of other countries.
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Radioactive waste management in developing countries
International Nuclear Information System (INIS)
Thomas, K.T.; Baehr, W.; Plumb, G.R.
1989-01-01
The activities of the Agency in waste management have therefore laid emphasis on advising developing Member States on the management of wastes from the uses of radioactive materials. At the present time, developing countries are mostly concerned with the management of nuclear wastes generated from medical centres, research institutes, industrial facilities, mining operations, and research reactors. In certain instances, management of such wastes has lapsed causing serious accidents. Radiation source mismanagement has resulted in fatalities to the public in Mexico (1962), Algeria (1978), Morocco (1984), and Brazil (1987). The objective of these activities is to support the countries to develop the required expertise for self-sufficiency in safe management of radioactive wastes. What follows are details of the Agency mechanisms in place to meet the above objectives
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Radiotherapy in developing countries
International Nuclear Information System (INIS)
1987-01-01
The Symposium presentations are divided into 6 chapters devoted to the following topics: radiation therapy for carcinoma of the cervix (6 papers), different approaches in radiation therapy (15 papers), hyperthermia (7 papers), chemical modifiers (7 papers), dosimetry and technology (5 papers), organization of radiation therapy in developing countries (5 papers). A separate abstract was prepared for each of these papers
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Building technological capability within satellite programs in developing countries
Wood, Danielle; Weigel, Annalisa
2011-12-01
This paper explores the process of building technological capability in government-led satellite programs within developing countries. The key message is that these satellite programs can learn useful lessons from literature in the international development community. These lessons are relevant to emerging satellite programs that leverage international partnerships in order to establish local capability to design, build and operate satellites. Countries with such programs include Algeria, Nigeria, Turkey, Malaysia and the United Arab Emirates. The paper first provides background knowledge about space activity in developing countries, and then explores the nuances of the lessons coming from the international development literature. Developing countries are concerned with satellite technology because satellites provide useful services in the areas of earth observation, communication, navigation and science. Most developing countries access satellite services through indirect means such as sharing data with foreign organizations. More countries, however, are seeking opportunities to develop satellite technology locally. There are objective, technically driven motivations for developing countries to invest in satellite technology, despite rich debate on this topic. The paper provides a framework to understand technical motivations for investment in satellite services, hardware, expertise and infrastructure in both short and long term. If a country decides to pursue such investments they face a common set of strategic decisions at the levels of their satellite program, their national context and their international relationships. Analysis of past projects shows that countries have chosen diverse strategies to address these strategic decisions and grow in technological capability. What is similar about the historical examples is that many countries choose to leverage international partnerships as part of their growth process. There are also historical examples from
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Managing nuclear knowledge in a developing country: Pakistan's perspective
International Nuclear Information System (INIS)
Ahmad, I.
2004-01-01
The nuclear technology base in a developing country is relatively much smaller compared to those in the industrialised countries. Thus, nuclear knowledge and its management are of great importance for those countries which are interested in nuclear technology but are still in the development phase. It is neither desirable nor possible to use imported nuclear technology as a black box. It is important for a developing country to acquire the ability for the safe and efficient operation of a nuclear facility such as a nuclear power plant. This should be done with maximum local participation and a sound institutional memory. (author)
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The Clean Development Mechanism: benefits of the CDM for developing countries. Executive summary
Energy Technology Data Exchange (ETDEWEB)
Pearce, D.; Day, B.; Newcombe, J.; Brunello, T.; Bello, T.
1998-11-01
This report is a summarized version of a 169 page report under the same title and authorship. The Kyoto Protocol to the Framework Convention on Climate Change enables countries with mandatory greenhouse gas reduction commitments to offset some of their domestic emissions by reductions in emissions and enhancement of carbon sinks in other countries. One of three types of offsets in the Protocol is the Clean Development Mechanism, a form of joint implementation between Annex 1 and non-Annex 1 countries which stresses the development gains to developing countries (Article 12). This report focuses on the provision of Article 12 and aims to establish a framework for determining the net benefits of such offsets or trades to developing countries. It looks at some estimates of the likely size of the CDM market, addresses the issue of risks, and takes a brief look at the issue of sharing credits between hosts and investors. It addresses how CDM projects might be screened for their contribution to sustainable development in developing countries and introduces the framework for assessing that contribution and then applies that framework to evaluate different types of potential CDM projects (in the energy, transport, forests and agricultural sectors). 10 tabs.
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Technology foresight and industrial strategy in developing countries
Pietrobelli, C.; Puppato, F.
2015-01-01
When Technology Foresight (TF) began to be adopted in industrial countries, it tended to be still somewhat a marginal activity in developing countries. It was then believed that TF and its prediction of the future was a matter that only highly industrialised countries could endeavour to achieve,
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Export Credit Insurances in Developing Countries: The Case of Turkey and IMT Countries
Directory of Open Access Journals (Sweden)
Cihat Koksal
2018-05-01
Full Text Available Export credit insurance is one of the substantial tools to promote export in a country. This paper endeavours to find out the effect of Export Credit Insurance covered by Export Credit Agencies on the developing countries’ export figures and GDP. The countries subject to the analysis are Turkey and Indonesia, Malaysia, Thailand also known as IMT Countries. The relationship between export value, economic growth and export credit insurances will be analyzed using Vector Autoregression (VAR Model.
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Directory of Open Access Journals (Sweden)
Cristina Boţa-Avram
2018-02-01
Full Text Available In the context of contemporary society, characterized by the information users’ growing and differentiated needs, the way country-level governance and social responsibility contribute to the ensuring of sustainable economic development is a concern for all the actors of the economic sphere. The aim of this paper is to test the causal linkages between the quality of country-level governance, economic growth and a well-known indicator of economic sustainable development, for a large panel of world-wide countries for a period of 10 years (2006–2015. While there are some prior studies that have argued the bidirectional causality between good public governance and economic development, this study intends to provide a new focus on the relationship between country-level governance and economic growth, on one hand, and between country-level governance and adjusted net savings, as a selected indicator of economic sustainable development, on the other hand. Four hypotheses on the causal relationship between good governance, economic growth and sustainable development were tested by using Granger non-causality tests. Our findings resulting from Granger non-causality tests provide reasonable evidence of Granger causality from country-level governance to economic growth, but from economic growth to country-level governance, the causality is not confirmed. In what regards the relationship between country-level governance and adjusted net savings, the bidirectional Granger causality is not confirmed. The main implication of our study is that improving economic growth and sustainable development is a very challenging issue, and the impact of macro-level factors such as country-level governance should not be neglected.
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Introduction: population migration and urbanization in developing countries.
Kojima, R
1996-12-01
This introductory article discusses the correlation between migration and rapid urbanization and growth in the largest cities of the developing world. The topics include the characteristics of urbanization, government policies toward population migration, the change in absolute size of the rural population, and the problems of maintaining megacities. Other articles in this special issue are devoted to urbanization patterns in China, South Africa, Iran, Korea and Taiwan as newly industrialized economies (NIEs), informal sectors in the Philippines and Thailand, and low-income settlements in Bogota, Colombia, and India. It is argued that increased urbanization is produced by natural population growth, the expansion of the urban administrative area, and the in-migration from rural areas. A comparison of urbanization rates of countries by per capita gross national product (GNP) reveals that countries with per capita GNP of under US$2000 have urbanization rates of 10-60%. Rates are under 30% in Africa, the Middle East, South Asia, China, and Indonesia. Rapid urbanization appears to follow the economic growth curve. The rate of urbanization in Latin America is high enough to be comparable to urbanization in Europe and the US. Taiwan and Korea have high rates of urbanization that surpass the rate of industrialization. Thailand and Malaysia have low rates of urbanization compared to the size of their per capita GNP. Urbanization rates under 20% occur in countries without economic development. Rates between 20% and 50% occur in countries with or without industrialization. East Asian urbanization is progressing along with industrialization. Africa and the Middle East have urbanization without industrialization. In 1990 there were 20 developing countries and 5 developed countries with populations over 5 million. In 10 of 87 developing countries rural population declined in absolute size. The author identifies and discusses four patterns of urban growth.
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Changing education through ICT in developing countries
DEFF Research Database (Denmark)
Georgsen, Marianne; Zander, Pär-Ola
This book presents discussions of how information and communication technology (ICT) can play a vital role in developing education and thereby developing communities, countries and regions.Through examples of current research in developing countries, a number of highly relevant questions and topics...... and education The chapters in this volume are written by members of the international research group on ICT for Development (ICT4D) at Aalborg University together with researchers from around the world. This book is the first of its kind to concentrate fully on the relationship between ICT for development...... in the context of education. The book is essential reading for researchers, educational planners, policy advisers, students and educators....
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Urban agriculture and poverty alleviation in developing countries ...
African Journals Online (AJOL)
Urban agriculture has served for a long time as a vital asset in the livelihood strategies of urban households in developing countries. It has been considered since then as a relevant input in responding to the embryonic economic situation of developing countries resulting to the structural adjustment programs and increasing ...
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Bringing developing countries into the energy equation
International Nuclear Information System (INIS)
Colombier, M.; Loup, J.; Laponche, Bernard; Martin-Amouroux, Jean-Marie; Chateau, Bertrand; Heller, Thomas C.; Kieken, Hubert; Kleiche, Mustapha; Mathy, Sandrine; Hourcade, Jean-Charles; Goldemberg, Jose; Pizer, William A.
2006-01-01
This compilation of articles on energy and climate change is a selection of contributions to the first edition of Regards sur la Terre, an annual reference in French on the international dimension of sustainable development, launched on the initiative of the French development agency, AFD (Agence francaise de developpement) and the institute for sustainable development and international relations, IDDRI (Institut du developpement durable et des relations internationales), and published by Presses de Sciences Po (Paris) in November 2006. Regards sur la terre includes an analysis of the most important international meetings and events of the last 12 months in the field of sustainable development, along with a thematic report, which focuses this year on energy and climate change. For almost two hundred years, the economic development of industrialized countries has gone hand in hand with growing consumption of fossil fuels, first coal, then oil and gas. The oil shocks of the 1970's had already revealed the fragility of this model, without however generating any major changes. The disconnection observed in the 1980's between a rapid return to economic growth and stagnating energy consumption was only provisional, and energy demand in the richest countries has again been rising since the 1990's; the development of alternative energy sources (nuclear power and renewables) has remained marginal and has failed to dethrone fossil fuels on which, paradoxically, the economies of industrialized countries are even more dependent today than they were 20 years ago. But with the turn of the century came major developments in the global energy landscape following the emergence of new and hitherto marginal actors: the rapid economic development of emerging countries is also dependent on an increasing supply of energy. Today this growing demand adds to tension on the oil and gas market, where the poorest countries are also the first victims. It could give new impetus to the
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Influence of diabetes mellitus on immunity to human tuberculosis.
Kumar Nathella, Pavan; Babu, Subash
2017-09-01
Type 2 diabetes mellitus(DM) is a major risk factor for the development of active pulmonary tuberculosis (TB), with development of DM pandemic in countries where TB is also endemic. Understanding the impact of DM on TB and the determinants of co-morbidity is essential in responding to this growing public health problem with improved therapeutic approaches. Despite the clinical and public health significance posed by the dual burden of TB and DM, little is known about the immunological and biochemical mechanisms of susceptibility. One possible mechanism is that an impaired immune response in patients with DM facilitates either primary infection with Mycobacterium tuberculosis or reactivation of latent TB. Diabetes is associated with immune dysfunction and alterations in the components of the immune system, including altered levels of specific cytokines and chemokines. Some effects of DM on adaptive immunity that are potentially relevant to TB defence have been identified in humans. In this review, we summarize current findings regarding the alterations in the innate and adaptive immune responses and immunological mechanisms of susceptibility of patients with DM to M. tuberculosis infection and disease. © 2017 John Wiley & Sons Ltd.
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Telemedicine for Developing Countries. A Survey and Some Design Issues.
Combi, Carlo; Pozzani, Gabriele; Pozzi, Giuseppe
2016-11-02
Developing countries need telemedicine applications that help in many situations, when physicians are a small number with respect to the population, when specialized physicians are not available, when patients and physicians in rural villages need assistance in the delivery of health care. Moreover, the requirements of telemedicine applications for developing countries are somewhat more demanding than for developed countries. Indeed, further social, organizational, and technical aspects need to be considered for successful telemedicine applications in developing countries. We consider all the major projects in telemedicine, devoted to developing countries, as described by the proper scientific literature. On the basis of such literature, we want to define a specific taxonomy that allows a proper classification and a fast overview of telemedicine projects in developing countries. Moreover, by considering both the literature and some recent direct experiences, we want to complete such overview by discussing some design issues to be taken into consideration when developing telemedicine software systems. We considered and reviewed the major conferences and journals in depth, and looked for reports on the telemedicine projects. We provide the reader with a survey of the main projects and systems, from which we derived a taxonomy of features of telemedicine systems for developing countries. We also propose and discuss some classification criteria for design issues, based on the lessons learned in this research area. We highlight some challenges and recommendations to be considered when designing a telemedicine system for developing countries.
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The validity of world class business criteria across developed and developing countries
Directory of Open Access Journals (Sweden)
Andre J. Parker
2010-11-01
Research purpose: To assess the validity of the general assumption in the literature that world class criteria are equally applicable worldwide. Motivation for research: The possibility exists that developing countries require an adjusted mix of world class criteria and practices to become globally competitive. Research design, approach and method: A quantitative field survey research approach was adopted. A web-enabled questionnaire was designed, covering 35 world class practices grouped under 7 world class criteria. A cross-section of the senior management from 14 developing and 20 developed country’s organisations partook in the study. Main findings: It was empirically confirmed that the majority of world class practices posited in the literature are used by participating organisations; that world class criteria do not apply equally across developed and developing countries; and that more important than country location, is the deliberate choice by an organisation’s leadership to become world class. An empirically based model of ascending to world class was proposed. Practical/managerial implications: Regardless of country location, the leadership of an organisation can make their organisation world class by applying the proposed world class model. Contribution/value add: A reliable web enabled instrument was designed that can be used to assess an organisation’s world class standing; the assumption that world class criteria are equally valid across developing and developed countries was proven partially incorrect; since becoming or being world class is also a leadership choice regardless of location.
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Total-factor energy efficiency in developing countries
International Nuclear Information System (INIS)
Zhang Xingping; Cheng Xiaomei; Yuan Jiahai; Gao Xiaojun
2011-01-01
This paper uses a total-factor framework to investigate energy efficiency in 23 developing countries during the period of 1980-2005. We explore the total-factor energy efficiency and change trends by applying data envelopment analysis (DEA) window, which is capable of measuring efficiency in cross-sectional and time-varying data. The empirical results indicate that Botswana, Mexico and Panama perform the best in terms of energy efficiency, whereas Kenya, Sri Lanka, Syria and the Philippines perform the worst during the entire research period. Seven countries show little change in energy efficiency over time. Eleven countries experienced continuous decreases in energy efficiency. Among five countries witnessing continuous increase in total-factor energy efficiency, China experienced the most rapid rise. Practice in China indicates that effective energy policies play a crucial role in improving energy efficiency. Tobit regression analysis indicates that a U-shaped relationship exists between total-factor energy efficiency and income per capita. - Research Highlights: → To measure the total-factor energy efficiency using DEA window analysis. → Focus on an application area of developing countries in the period of 1980-2005. → A U-shaped relationship was found between total-factor energy efficiency and income.
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Lee, Cecilia; Robinson, Joan L
2016-06-01
The efficacy of immunization mandates for childcare or school entry is a long-standing controversy. The United States (US) adopted school entry immunization mandates in the 1800s, while most countries still do not have mandates. The objective of this systematic review was to analyze the evidence that immunization uptake increases with mandates. A search was conducted for studies that compared immunization uptake in a population prior to and after mandates, or in similar populations with one group having and the other not having mandates. Data were extracted and synthesized qualitatively due to the heterogeneity of study design. Eleven before-and-after studies and ten studies comparing uptake in similar populations with and without mandates were included. Studies were from the US (n = 18), France (n = 1) and Canada (n = 2). Eleven of the 21 studies looked at middle school mandates. All but two studies showed at least a trend towards increased uptake with mandates. Higher uptake was associated with a more long-standing mandate. Immunization mandates have generally led to increased short-term and long-term uptake in the group to whom the mandate applies. Many studies have centered around middle school mandates in the US and there is a paucity of studies of childcare mandates or of studies of mandates in other countries or in settings with relatively high baseline immunization uptake. Copyright © 2016 The British Infection Association. Published by Elsevier Ltd. All rights reserved.
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Dynamic functional studies in nuclear medicine in developing countries
International Nuclear Information System (INIS)
1989-01-01
The Proceedings document some of the trials and tribulations involved in setting up nuclear medicine facilities in general and specifically as regards nuclear medicine applications for the diagnosis of the diseases prevalent in the less developed countries. Most of the 51 papers deal with various clinical applications of dynamic functional studies. However, there was also a session on quality control of the equipment used, and a panel discussion critically looked at the problems and potential of dynamic studies in developing countries. This book will be of interest and use not only to those practising nuclear medicine in the developing countries, but it may also bring home to users in developed countries how ''more can be done with less''. Refs, figs and tabs
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Childhood overweight, obesity, and the metabolic syndrome in developing countries.
Kelishadi, Roya
2007-01-01
The incidence of chronic disease is escalating much more rapidly in developing countries than in industrialized countries. A potential emerging public health issue may be the increasing incidence of childhood obesity in developing countries and the resulting socioeconomic and public health burden faced by these countries in the near future. In a systematic review carried out through an electronic search of the literature from 1950-2007, the author compared data from surveys on the prevalence of overweight, obesity, and the metabolic syndrome among children living in developing countries. The highest prevalence of childhood overweight was found in Eastern Europe and the Middle East, whereas India and Sri Lanka had the lowest prevalence. The few studies conducted in developing countries showed a considerably high prevalence of the metabolic syndrome among youth. These findings provide alarming data for health professionals and policy-makers about the extent of these problems in developing countries, many of which are still grappling with malnutrition and micronutrient deficiencies. Time trends in childhood obesity and its metabolic consequences, defined by uniform criteria, should be monitored in developing countries in order to obtain useful insights for primordial and primary prevention of the upcoming chronic disease epidemic in such communities.
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Moms, babies, and bugs in immune development [version 1; referees: 2 approved
Directory of Open Access Journals (Sweden)
Katie Alexander
2017-12-01
Full Text Available Bacteria and mammals have co-evolved with one another over millennia, and it has become impossible to interpret mucosal immunity without taking the microbiota into consideration. In fact, the primary role of the mucosal immune system is regulating homeostasis and the host relationship with the microbiota. Bacteria are no longer seen as simply invading pathogens, but rather a necessary component to one’s own immune response. On the one hand, the microbiota is a vital educator of immune cells and initiator of beneficial responses; but, on the other, dysbiosis of microbiota constituents are associated with inflammation and autoimmune disorders. In this review, we will consider recent advances in the understanding of how the microbiota influences host mucosal immunity, particularly the initial development of the immune response and its implications.
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Directory of Open Access Journals (Sweden)
Seung-Hoon Yoo
2001-12-01
Full Text Available Evaluating the sources of economic development is of obvious importance, and numerous attempts have been made to judge the impact of many different factors on economic development. Since some empirical studies have reported that telecommunications investment is one of the important factors in economic development, this paper empirically investigates the impact of telecommunications investment on economic development using a cross-country analysis based on data from 56 developing countries for the years 1970-98. To this end, a further augmented version of the neoclassical Solow growth model is suggested and applied. Subject to the appropriate caveats, the results provide further support for several key conclusions of the former studies - investment in physical capital, population growth, and human capital seem to be quite important in accounting for economic development in developing countries. In addition, more importantly, it is concluded that telecommunications investment significantly contributes to economic development in the developing world.
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Nuclear cardiology for developing countries
International Nuclear Information System (INIS)
Feinendegen, L.E.
1986-01-01
The role of nuclear medicine in developing countries must be oriented to the local needs for clinical practice, the health care of large populations and the demands for research with sometimes extremely limited resources. To help define the locally differing needs, it is stressed that nuclear medicine provides the unique opportunity to observe the body at the molecular level of organization and thus makes the body biochemically transparent. Depending on the particular diagnostic demands, complex imaging with gamma scintigraphy or emission tomography may be the only method to choose in some instances, but for others it may be an unnecessary luxury. Nuclear cardiology, with the purpose of non-invasively assessing cardiac function, myocardial perfusion and myocardial metabolism, is a particular challenge in both respects for developing countries. Given such requirements, single-probe devices with multipurpose application are less expensive than gamma cameras and promise advanced diagnostic uses. In one examination, left ventricular function, global cardio-pulmonary circulation and the general circulatory adaptation to exercise can be investigated by non-gated simultaneous blood pool measurements over four lung regions, the heart and the liver. In addition, such devices have the advantages of compactness, robustness and electronic stability. Despite enormous difficulties regarding funding, infrastructure, equipment and maintenance, developing countries should be encouraged to participate in the evolution of nuclear medicine by responding and adapting to defined needs and perhaps by maintaining at least one national centre of excellence with capacities for research and training. Funds are best secured by providing an indispensable service in co-operation with the various clinical disciplines. (author)
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Status of National Minorities in Developed European Countries
Directory of Open Access Journals (Sweden)
Nada Raduški
2008-09-01
Full Text Available Contemporary geopolitical changes, interethnic conflicts and clashes, and the connection between minority and territorial problems considerably influence the quality of inter-state relations and the preservation of global peace and security. National problems and ethnic confrontations found a firm ground on the territory of the Balkans, although they are known in democratic West-European countries as well, despite high standards in respecting human rights. However, even though they deserve special attention due to their seriousness, they remain exclusively under those countries’ jurisdiction, as opposed to countries in transition that are in the focus of interest and intervention of the international community. In developed countries, the method of regulating the minority question greatly depends on the position of that country on the world economic and political scene, apart from numerous historical and political factors. In each of these countries, there are specific models of coexistence of majority and minority population conditioned by numerous factors, so there does not exist a universal model that would be valid for all countries. Respecting basic human rights, as well as national minority protection, represent the basic factors of the stability, and democratic and socio-economic development of every country.
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Head and Neck Cancers in Developing Countries
Directory of Open Access Journals (Sweden)
Poonam Joshi
2014-04-01
Full Text Available Head and neck cancers are the most common cancers in developing countries, especially in Southeast Asia. Head and neck cancers are more common in males compared to females. This is mainly attributed to tobacco, areca nut, alcohol, etc. Oral cancers are most common amongst all head and neck squamous cell cancers (HNSCC. HNSCC in the developing world differ from those in the Western world in terms of age, site of disease, etiology, and molecular biology. Poverty, illiteracy, advanced stage at presentation, lack of access to health care, and poor treatment infrastructure pose a major challenge in management of these cancers. The annual GDP (gross domestic product spent on health care is very low in developing countries compared to the developed countries. Cancer treatment leads to a significant financial burden on the cancer patients and their families. Several health programs have been implemented to curb this rising burden of disease. The main aims of these health programs are to increase awareness among people regarding tobacco and to improve access to health care facilities, early diagnosis, treatment, and palliative care.
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The gender wage gap in developed countries
Kunze, Astrid
2017-01-01
Despite the increased attachment of women to the labour force in nearly all developed countries, a stubborn gender pay gap remains. This chapter provides a review of the economics literature on the gender wage gap, with an emphasis on developed countries. We begin with an overview of the trends in the gender differences in wages and employment rates. We then review methods used to decompose the gender wage gap and the results from such decompositions. We discuss how trends and differences in ...
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Female labor force participation in developing countries
Verick, Sher
2014-01-01
While women’s labor force participation tends to increase with economic development, the relationship is not straightforward or consistent at the country level. There is considerably more variation across developing countries in labor force participation by women than by men. This variation is driven by a wide variety of economic and social factors, which include economic growth, education, and social norms. Looking more broadly at improving women’s access to quality employment, a critica...
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Sanitation planning in developing countries
Kerstens, S.M.
2016-01-01
Sanitation planning in developing countries: Added value of resource recovery
Worldwide 2.5 billion people lack access to sanitation. This impacts human live, the environment and represents a loss of valuable resources that can be regained from wastewater. This study
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Proposed Special Issue: Progress of cancer research in developing countries
Directory of Open Access Journals (Sweden)
T.S. Jong
2016-10-01
Full Text Available As developing economies[1] around the world become more socially affluent in the coming decades, the incidence of cancer-related mortality is expected rise significantly owing to a combination of lifestyle changes and multiple environmental factors (Figure 1. Based on statistics from the World Health Organization, developing countries accounted for nearly 72% of cancer mortality in 2008 even though the average disease incidence in these countries is lower compared to that of high-income nations[3]It has been projected that up to 60% (ca. 15–20 million of new cancer cases will occur in developing countries by the year 2020[4-6], causing more deaths than AIDS, malaria, and tuberculosis combined. In the past, cancer management in developing countries has focused heavily on disease prevention, general awareness improvement, and early detection, while deprioritizing treatment and research efforts as a result of limited resources[7]. However, given the severity of the situation, it is now necessary to recalibrate our focus and reprioritize the investment of valuable resources in the fight against cancer.With respect to cancer research in developing countries, a major challenge faced by international researchers is the lack of reliable data[6], along with a limited research output from the developing world, which hampers our general understanding of the capability of these countries in dealing with the cancer pandemic. From 2011 to 2015, the average combined research output from developing countries constituted only 20% of the total publication output of the world’s top 100 most published countries in the field of oncology (Figure 2. Nonetheless, developing countries have recorded an impressive 20% average year-on-year increase in terms of their publication output during this period, and five of these countries contributed to more than three quarter of the total number of papers published (Figure 3.In contrast, developed nations only registered a 4
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Changing education through ICT in developing countries
DEFF Research Database (Denmark)
Georgsen, Marianne; Zander, Pär-Ola
This book presents discussions of how information and communication technology (ICT) can play a vital role in developing education and thereby developing communities, countries and regions.Through examples of current research in developing countries, a number of highly relevant questions and topics...... are dealt with, such as: • Approaches to user involvement and participation in development • Knowledge and its role in development, particularly in higher education • Digital literacy and ways of developing it • Pedagogic approaches • Learning cultures in globalised education • Teacher training...... and education The chapters in this volume are written by members of the international research group on ICT for Development (ICT4D) at Aalborg University together with researchers from around the world. This book is the first of its kind to concentrate fully on the relationship between ICT for development...
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Implementation of sustainable energy programs in developing countries
International Nuclear Information System (INIS)
Spitalnik, J.
2001-01-01
Energy, a major contributor to development, is an essential element for increasing quality of life. During the next decades, the developing world will experience an explosive increase of energy demand, requiring enormous efforts and ingenuity to be fully satisfied. Delays may create public frustration for not achieving paradigm levels of quality of life, giving eventually rise to serious pressures on governments. The concept of sustainable energy options for development cannot be analyzed under the same prism in developed and developing countries. The relative degree of a country development should be introduced when setting up the path to sustainable development. (author)
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Climate policy in developing countries and conditional transfers
International Nuclear Information System (INIS)
Ruebbelke, Dirk T.G.
2006-01-01
This paper analyzes the role international transfers may play in international climate policy in consideration of the policy's ancillary benefits, such as air quality improvements. Ancillary benefits are especially important in many developing countries, while climate protection benefits or primary benefits play a minor role on the political agenda of these countries. In contrast, industrialized countries have a strong interest in combating climate change. These often neglected asymmetries between the developing and industrialized world affect the impacts of transfers. Interestingly, as we will show, the cost differentials between different environmental technologies among countries are the crucial prerequisite for the functioning of a transfer scheme and not the cost differentials in the execution of climate policy. This result has been overlooked by standard pure public good approaches
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The burden of non communicable diseases in developing countries
Directory of Open Access Journals (Sweden)
Boutayeb Abdesslam
2005-01-01
Full Text Available Abstract Background By the dawn of the third millennium, non communicable diseases are sweeping the entire globe, with an increasing trend in developing countries where, the transition imposes more constraints to deal with the double burden of infective and non-infective diseases in a poor environment characterised by ill-health systems. By 2020, it is predicted that these diseases will be causing seven out of every 10 deaths in developing countries. Many of the non communicable diseases can be prevented by tackling associated risk factors. Methods Data from national registries and international organisms are collected, compared and analyzed. The focus is made on the growing burden of non communicable diseases in developing countries. Results Among non communicable diseases, special attention is devoted to cardiovascular diseases, diabetes, cancer and chronic pulmonary diseases. Their burden is affecting countries worldwide but with a growing trend in developing countries. Preventive strategies must take into account the growing trend of risk factors correlated to these diseases. Conclusion Non communicable diseases are more and more prevalent in developing countries where they double the burden of infective diseases. If the present trend is maintained, the health systems in low-and middle-income countries will be unable to support the burden of disease. Prominent causes for heart disease, diabetes, cancer and pulmonary diseases can be prevented but urgent (preventive actions are needed and efficient strategies should deal seriously with risk factors like smoking, alcohol, physical inactivity and western diet.
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Development of Global Change Research in Developing Countries
Sierra, Carlos A.; Yepes, Adriana P.
2010-10-01
Ecosystems and Global Change in the Context of the Neotropics; Medellín, Colombia, 19-20 May 2010; Research in most areas of global environmental change is overwhelmingly produced outside developing countries, which are usually consumers rather than producers of the knowledge associated with their natural resources. While there have been important recent advances in understanding the causes of global-¬scale changes and their consequences to the functioning of tropical ecosystems, there is still an important gap in the understanding of these changes at regional and national levels (where important political decisions are usually made). A symposium was held with the aim of surveying the current state of research activities in a small, developing country such as Colombia. It was jointly organized by the Research Center on Ecosystems and Global Change, Carbono and Bosques; the National University of Colombia at Medellín and the Colombian Ministry of the Environment, Housing, and Regional Development. This 2-¬day symposium gathered Colombian and international scientists involved in different areas of global environmental change, tropical ecosystems, and human societies.
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R.D. Semba; M. Muhilal; N.E. Mohgaddam (Nasrin); Z. Munasir; A. Akib; D. Permaesih; M.S. Muherdiyantiningsih; A.D.M.E. Osterhaus (Albert)
1999-01-01
textabstractChildhood immunization programs may provide infrastructure for delivering vitamin A supplements to infants in developing countries. The effect of giving vitamin A, an immune enhancer, on antibody responses to trivalent oral poliovirus vaccine (TOPV) is unknown. A
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Directory of Open Access Journals (Sweden)
Talknice Saungweme
2013-09-01
Full Text Available The study analyses trends in Official Development Assistance (ODA to developing countries, mainly Africa, and possibilities of new financing instruments. Economies of most developing countries, especially those in Sub-Saharan Africa, are characterised by low investment flows, huge import bills and lower exports. Subsequently, development assistance is the major source of external finance and has taken the form of budget support, humanitarian and development finance. However, the noted fall in ODA in 2005, 2009 and 2012 might adversely impact directly on the attainment of millennium development goals in 2015. This negative trend in ODA is a result of a combination of factors such as economic constraints in the donor countries (for example, the debt crisis and/or a new shift in financing mechanisms to developing countries.
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Energy and economic development [Brazil: A country profile on sustainable energy development
International Nuclear Information System (INIS)
Machado, G.; Schaeffer, R.
2006-01-01
When energy specialists discuss the relationships between energy use and economic development, the focus is usually on how energy supports economic growth, alleviates poverty and increases people's well-being. On rare occasions, though, the effect that a country's choices for promoting economic development have on energy production and use is a matter of concern. The purpose of this chapter is to evaluate the way Brazil's choices for promoting economic development over time have impacted primary and final energy use in the country. Economic growth has different levels of quality, which lead to different economic development paths. Some paths are more effective than others in creating wealth and in protecting and preserving natural resources and the environment for future generations. Quality actually matters as much for economic development as for energy. This chapter is divided into four sections covering energy and economic development relationships, the evolution of final energy use in Brazil, strategies to enhance sustainable energy development in the country and a summary of main issues. In Section 5.1, energy and economic development relationships are discussed, setting the background for the analysis of the impacts on final energy use of some of Brazil's choices for promoting economic development. The section begins by focusing on the basics of energy and economic development relationships. It should be noted that most energy specialists usually discuss only the basics of energy and economic development (the 'energy in support of economic development' theme), but this approach alone is not enough to explain differences in countries' final energy use patterns, or to identify strategies to enhance sustainable energy development. In this sense, the main contribution of this section is to further illuminate the role of social and economic choices in determining the effectiveness of a given country's economic development and that country's primary and final
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Djingarey, Mamoudou H.; Diomandé, Fabien V. K.; Barry, Rodrigue; Kandolo, Denis; Shirehwa, Florence; Lingani, Clement; Novak, Ryan T.; Tevi-Benissan, Carol; Perea, William; Preziosi, Marie-Pierre; LaForce, F. Marc
2015-01-01
Background. A group A meningococcal conjugate vaccine (PsA-TT) was developed specifically for the African “meningitis belt” and was prequalified by the World Health Organization (WHO) in June 2010. The vaccine was first used widely in Burkina Faso, Mali, and Niger in December 2010 with great success. The remaining 23 meningitis belt countries wished to use this new vaccine. Methods. With the help of African countries, WHO developed a prioritization scheme and used or adapted existing immunization guidelines to mount PsA-TT vaccination campaigns. Vaccine requirements were harmonized with the Serum Institute of India, Ltd. Results. Burkina Faso was the first country to fully immunize its 1- to 29-year-old population in December 2010. Over the next 4 years, vaccine coverage was extended to 217 million Africans living in 15 meningitis belt countries. Conclusions. The new group A meningococcal conjugate vaccine was well received, with country coverage rates ranging from 85% to 95%. The rollout proceeded smoothly because countries at highest risk were immunized first while attention was paid to geographic contiguity to maximize herd protection. Community participation was exemplary. PMID:26553672
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Energy and economic development in Lithuania and neighbouring countries
International Nuclear Information System (INIS)
Jankauskas, V.; Shtremeikiene, D.
1995-01-01
In Lithuania as also in neighbouring countries (Poland, Latvia, Belarus, Russia) economic reforms are going on. All these countries, better or worse, slower or quicker, are restructuring their economies from centrally planned into market based ones. The neighbouring countries also are the main Lithuania's trading partners, and Russia is a sole supplier of crude oil and natural gas. This article deals with the analysis of the latest economic development in Lithuania and in neighbouring countries, as well as with it impact on the development of the Lithuanian energy sector. The analysis is based on the statistical data of the last few years and on some projections of future development. (author). 12 refs., 7 tabs., 21 figs
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Scope of nuclear medicine in the developing countries
International Nuclear Information System (INIS)
Ganatra, R.D.
1992-01-01
What should a developing country do to promote nuclear medicine? Practice of nuclear medicine requires sophisticated electronic instruments and a variety of radiopharmaceuticals. Ideal situation would be when both are obtainable from local sources. It is not an easy task for developing countries to produce these electronic marvels locally. It anticipates a widespread electronics industry in a country so that various components which go in the big machines are also made locally. One, who has worked in a developing country would realize how exasperating a task it is to maintain, service and repair imported instruments. They break down often in the tropics, are difficult to service due to lack of spare parts and their down-time unusually long. Many of the modern instruments have lots of ''frills and laces'' and as a policy, it is prudent to purchase something which is ''bare to bones'' and simple to use but still capable of providing the essential range of applications
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Scope of nuclear medicine in the developing countries
Energy Technology Data Exchange (ETDEWEB)
Ganatra, R D
1993-12-31
What should a developing country do to promote nuclear medicine? Practice of nuclear medicine requires sophisticated electronic instruments and a variety of radiopharmaceuticals. Ideal situation would be when both are obtainable from local sources. It is not an easy task for developing countries to produce these electronic marvels locally. It anticipates a widespread electronics industry in a country so that various components which go in the big machines are also made locally. One, who has worked in a developing country would realize how exasperating a task it is to maintain, service and repair imported instruments. They break down often in the tropics, are difficult to service due to lack of spare parts and their down-time unusually long. Many of the modern instruments have lots of ``frills and laces`` and as a policy, it is prudent to purchase something which is ``bare to bones`` and simple to use but still capable of providing the essential range of applications
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Educating Civil Engineers for Developing Countries
Stanley, D.
1974-01-01
Based on engineering teaching experience in Africa and Asia, ideas are presented on educating civil engineers for developing countries, especially those in Africa. Some of the problems facing educational planners, teachers, and students are addressed, including responsibilities of a newly graduated civil engineer, curriculum development, and…
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Immune Regulator MCPIP1 Modulates TET Expression during Early Neocortical Development
Directory of Open Access Journals (Sweden)
Huihui Jiang
2016-09-01
Full Text Available MCPIP1 is a recently identified immune regulator that plays critical roles in preventing immune disorders, and is also present in the brain. Currently an unresolved question remains as to how MCPIP1 performs its non-immune functions in normal brain development. Here, we report that MCPIP1 is abundant in neural progenitor cells (NPCs and newborn neurons during the early stages of neurogenesis. The suppression of MCPIP1 expression impairs normal neuronal differentiation, cell-cycle exit, and concomitant NPC proliferation. MCPIP1 is important for maintenance of the NPC pool. Notably, we demonstrate that MCPIP1 reduces TET (TET1/TET2/TET3 levels and then decreases 5-hydroxymethylcytosine levels. Furthermore, the MCPIP1 interaction with TETs is involved in neurogenesis and in establishing the proper number of NPCs in vivo. Collectively, our findings not only demonstrate that MCPIP1 plays an important role in early cortical neurogenesis but also reveal an unexpected link between neocortical development, immune regulators, and epigenetic modification.
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Sustainable energy issues in developing countries
Energy Technology Data Exchange (ETDEWEB)
Munasinghe, M [Environmental Policy Division, The World Bank, Washington D.C. (US)
1991-07-01
Increased energy use is a vital pre-requisite for economic development, and less developing countries (LDCs) are struggeling to meet energy needs at acceptable costs. LDC decision-makers share the worldwide environmental concerns, but also face other urgent issues like poverty. The industrialised countries can afford to substitute environmental protection for further material growth, but the LDCs will need concessional funding to participate in addressing global environmental problems. Global financing issues may be analysed and resolved through tradeoffs among several criteria including affordability/additionality, fairness/equity, and economic efficiency. The short-term LDC response to sustainable energy issues will be limited mainly to conventional technologies in efficiency improvements, conservation and resource development. The industrialised nations should provide financial resources to LDCs and develop the technology to be used in the 21st century. Pilot international funds like the Global Environmental Facility and the Ozone Fund will help LDCs participate in the effort to solve global environmental issues. (author) 16 refs.
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A strategy to improve priority setting in developing countries.
Kapiriri, Lydia; Martin, Douglas K
2007-09-01
Because the demand for health services outstrips the available resources, priority setting is one of the most difficult issues faced by health policy makers, particularly those in developing countries. Priority setting in developing countries is fraught with uncertainty due to lack of credible information, weak priority setting institutions, and unclear priority setting processes. Efforts to improve priority setting in these contexts have focused on providing information and tools. In this paper we argue that priority setting is a value laden and political process, and although important, the available information and tools are not sufficient to address the priority setting challenges in developing countries. Additional complementary efforts are required. Hence, a strategy to improve priority setting in developing countries should also include: (i) capturing current priority setting practices, (ii) improving the legitimacy and capacity of institutions that set priorities, and (iii) developing fair priority setting processes.
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SMEs, Competition and Entry - A developing country perspective
DEFF Research Database (Denmark)
Jensen, Camilla
The paper develops a simple model for a developing country with a dual economic structure. The model is a further theoretical extension and empirical work to an earlier published book chapter on the same topic. The abstract was updated after presentation at the conference in Gold Coast, Australia....... The main research question is why it is so difficult for new entrepreneurs to enter markets, or in other words, why are the barriers to entry seemingly higher in developing countries? Development writers such as Hernando de Soto and Daron Acemoglu suggest that this question is closely related...... with a sizeable informal sector in developing countries and corruption. Other leading transition researchers such as Andrei Shleifer offer a variety of views on the informal sector from the romantic to the parasitic. This paper leans on the realist interpretation of de Soto grounded in institutional theory. High...
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Radiation injury of the developing immune system in the beagle dog
International Nuclear Information System (INIS)
Miller, G.K.
1982-01-01
Fetal lymphoid organs of the beagle dog were studied to determine if the developing immune system displays an age-dependent sensitivity to ionizing radiation. Pregnant beagle dams received abdominal 60 Co gamma exposures to 200R or were sham irradiated at one of three ages in gestation; 35, 40, or 45 days postcoitus. The mean calculated dose to each fetus was 1.5 Gy. Half the fetuses in each litter were harvested by hysterotomy at five days and half at ten days postirradiation (PI). The volumes of the thymus lobules and lobular cortices were significantly reduced at five and ten days PI as compared to age matched controls. Radiation damage in the developing immune system was expressed in the lymphocyte populations of fetal lymphoid organs and in thymus epithelium. Damage was qualitatively and quantitatively more severe following irradiation earlier in gestation, confirming that the developing immune system displays an age-dependent sensitivity. Prenatal radiation injury to the developing lymphoid system could compromise postnatal immunologic function and could alter immunoregulation
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Waste management advisory missions to developing countries
International Nuclear Information System (INIS)
Thomas, K.T.
1990-01-01
The IAEA's Waste Management Advisory Programme (WAMAP) was initiated in 1987 as an interregional technical co-operation project to complement other activities in radioactive waste management. Its creation gave greater recognition to the importance of the safe management of radioactive wastes and promotion of long-term waste management technical assistance strategies for developing countries. Over the past 4 years, international experts have reviewed the radioactive waste management programmes of 29 developing countries. Missions have been conducted within the framework of the IAEA's Waste Management Advisory Programme (WAMAP). Ten of these countries have nuclear power plants in operation or under construction or have nuclear fuel cycle facilities. Altogether, 23 have research reactors or centres, eight have uranium or thorium processing programmes or wastes, and nine essentially have only isotope applications involving the use of radiation sources
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What Makes MNCs Succeed in Developing Countries?
DEFF Research Database (Denmark)
Hansen, Michael W.; Gwozdz, Wencke
2015-01-01
) are increasingly establishing subsidiaries in developing countries. The potential gains are high; however, so are the risks. While the issue of subsidiary performance should be at the heart of any international business (IB) enquiry into MNC activity in developing countries, surprisingly little research has...... examined this issue. Design/methodology/approach – Based on a comprehensive literature review of the IB performance literature, it is hypothesized that subsidiary performance essentially is shaped by five clusters of factors: location, industry, MNC capabilities, subsidiary role and entry strategy...
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Problems of radiation therapy in developing countries
Energy Technology Data Exchange (ETDEWEB)
Lyimo, R; Neumeister, K
1988-01-01
Poverty as well as lack of proper cancer programmes has prevented the early detection of cancer in developing countries. Radiotherapy is applied mostly in advanced cases only. To change the situation comprehensive programmes must be introduced with particular attention to the importance of cancer control. The establishment of cancer societies as well as the introduction of centres for training of radiological personnel will really improve the situation. A realistic method for the optimization of radiotherapy in developing countries should be the use of radiomodification such as hypoxyradiotherapy.
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Cephalic Tetanus in an Immunized Teenager: An Unusual Case Report.
Felter, Robert A; Zinns, Lauren E
2015-07-01
Tetanus is a rare disease in developed countries but is prevalent worldwide. It has significant morbidity and mortality. The causative agent Clostridium tetani is ubiquitous in nature. In the United States, approximately 50 to 100 cases are reported per year but rarely in immunocompetent, fully immunized patients. Of the four types of tetanus (generalized, neonatal, cephalic, and localized), cephalic is the least common. We present a case of cephalic tetanus in a 14-year-old boy who completed his primary immunizations with a video of his physical examination findings.
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Report on WHO meeting on immunization in older adults: Geneva, Switzerland, 22–23 March 2017
Aguado, M. Teresa; Barratt, Jane; Beard, John R.; Blomberg, Bonnie B.; Chen, Wilbur H.; Hickling, Julian; Hyde, Terri B.; Jit, Mark; Jones, Rebecca; Poland, Gregory A.; Ortiz, Justin R.
2018-01-01
Many industrialized countries have implemented routine immunization policies for older adults, but similar strategies have not been widely implemented in low- and middle-income countries (LMICs). In March 2017, the World Health Organization (WHO) convened a meeting to identify policies and activities to promote access to vaccination of older adults, specifically in LMICs. Participants included academic and industry researchers, funders, civil society organizations, implementers of global health interventions, and stakeholders from developing countries with adult immunization needs. These experts reviewed vaccine performance in older adults, the anticipated impact of adult vaccination programs, and the challenges and opportunities of building or strengthening an adult and older adult immunization platforms. Key conclusions of the meeting were that there is a need for discussion of new opportunities for vaccination of all adults as well as for vaccination of older adults, as reflected in the recent shift by WHO to a life-course approach to immunization; that immunization in adults should be viewed in the context of a much broader model based on an individual’s abilities rather than chronological age; and that immunization beyond infancy is a global priority that can be successfully integrated with other interventions to promote healthy ageing. As WHO is looking ahead to a global Decade of Healthy Ageing starting in 2020, it will seek to define a roadmap for interdisciplinary collaborations to integrate immunization with improving access to preventive and other healthcare interventions for adults worldwide. PMID:29336923
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Eradication of poliomyelitis in countries affected by conflict.
Tangermann, R H; Hull, H F; Jafari, H; Nkowane, B; Everts, H; Aylward, R B
2000-01-01
The global initiative to eradicate poliomyelitis is focusing on a small number of countries in Africa (Angola, Democratic Republic of the Congo, Liberia, Sierra Leone, Somalia, Sudan) and Asia (Afghanistan, Tajikistan), where progress has been hindered by armed conflict. In these countries the disintegration of health systems and difficulties of access are major obstacles to the immunization and surveillance strategies necessary for polio eradication. In such circumstances, eradication requires special endeavours, such as the negotiation of ceasefires and truces and the winning of increased direct involvement by communities. Transmission of poliovirus was interrupted during conflicts in Cambodia, Colombia, El Salvador, Peru, the Philippines, and Sri Lanka. Efforts to achieve eradication in areas of conflict have led to extra health benefits: equity in access to immunization, brought about because every child has to be reached; the revitalization and strengthening of routine immunization services through additional externally provided resources; and the establishment of disease surveillance systems. The goal of polio eradication by the end of 2000 remains attainable if supplementary immunization and surveillance can be accelerated in countries affected by conflict.
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The Existence of Long-Run PPP: A Comparison between Developed and Developing Countries
Directory of Open Access Journals (Sweden)
Sulistiadi Dono Iskandar
2016-08-01
Full Text Available McNown & Wallace (1989 argued that PPP will tend to holds in less developed countries due to the domination of nominal factors in the economy. In this study we try to investigate the existence of long-run PPP in eight countries consisting four developed and developing countries. Here we show that there is a strong evidence that long-run PPP holds for Germany, United Kingdom, and Chile. Furthermore, the additional tests also show that symmetry and proportionality conditions seem to hold in the three economies. As for other five economies, long-run PPP seems to be absence. Although one step general Error Correction Model and Johansen-Juselius cointegration procedure generates conflicting result, the result of both technique do not show a tendency for PPP to hold in developing countries thus rejecting argument proposed by McNown and Wallace.
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OpportunitiesandPerceptionofSpaceProgramsintheDevelopingCountries
Abubakar, B.
2007-05-01
Although the space program as a whole is a true reflection of the level of achievement in human history in the field of Science and Technology, but it is also important to note that there are numbers of communities and societies on this earth that are ignorant about this great achievement, hence leading to the continuous diverting of Potential Astronomers, Aerospace Engineers and Astrologist to other disciplines, thereby undermining the development of the space program over time. It was in view of the above that this research was conducted and came up with the under listed Suggestions/Recommendations:- (1) The European Space Agency (ESA), National Aeronautic Space Agency (NASA) and the Russian Space Agency, should be organising and sponsoring public enlightenment conferences, seminars and workshops towards creating awareness and attracting Potential Astronomers and other Space Scientist mostly in the developing countries into the space program. (2) Esteemed organisations in space programs like NASA, ESA and others should be awarding scholarships to potential space scientist that lacks the financial capability to pursue studies in the field of space science from the developing countries. (3) The European Space Agency, National Aeronautic Space Agency and the Russian Space Agency, should open their offices for the development of the space program in the third world countries. I believe that if the above suggestions/recommendations are adopted and implemented it will lead to the development of the space program in general, otherwise the rate at which potential Astronomers, Aerospace Engineers and Astrologists will be diverting into other disciplines will ever remain on the increase. Thanks for listening.
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Nuclear power in developing countries
International Nuclear Information System (INIS)
Lane, J.A.; Covarrubias, A.J.; Csik, B.J.; Fattah, A.; Woite, G.
1977-01-01
This paper is intended to be a companion to similar papers by OECD/NEA and CMEA and will summarize the nuclear power system plans of developing Member States most likely to have nuclear programmes before the year 2000. The information that is presented is derived from various sources such as the Agency 1974 study of the market for nuclear power in developing countries, the annual publication, ''Power Reactors in Member States - 1976 Edition'', various nuclear power planning studies carried out by the Agency during the period 1975 and 1976, direct correspondence with selected Member States and published information in the open literature. A preliminary survey of the prospects for nuclear power in Member States not belonging to the OECD or having centrally planned economies indicates that about 27 of these countries may have operating nuclear power plants by the end of the century. In the 1974 Edition of the ''Market Survey'' it was estimated that the installed nuclear capacity in these countries might reach 24 GW by 1980, 157 GW by 1190 and 490 GW by the year 2000. It now appears that these figures are too high for a number of reasons. These include 1) the diminished growth in electrical demand which has occurred in many Member States during the last several years, 2) the extremely high cost of nuclear plant construction which has placed financial burdens on countries with existing nuclear programmes, 3) the present lack of commercially available small and medium power reactors which many of the smaller Member States would need in order to expand their electric power systems and 4) the growing awareness of Member States that more attention should be paid to exploitation of indigenous energy sources such as hydroelectric power, coal and lignite
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Manpower requirements for nuclear power in developing countries
International Nuclear Information System (INIS)
Csik, B.J.
1980-01-01
It is recognized that each country has its individual unique characteristics and that there is no typical or average developing country. Common conditions represent exceptions, rather than the rule. Manpower requirements, however, are created by the tasks to be performed and activities to be carried out at each definite stage of a nuclear power project or programme. These tasks and activities, as well as the manpower requirements they create, are of a similar nature for any country, subject to the influence of prevailing local conditions. First, successive stages of the evolution of a nuclear power programme are defined. These are: pre-planning, planning, study and procurement, construction, operation of the first plant, confirmed and self-sufficient in implementing nuclear power projects. The developing countries are then classified according to the present stage of their evolution. Finally, the present and future manpower requirements of each country or group of countries are estimated. No attempt has been made to try to establish any precise data for any country in particular. The results obtained are global estimates, intended as indications of trends and of orders of magnitude. It is found that the developing world's present manpower requirements for nuclear power are of the order of 100,000 people, of which about 20,000 need specialized nuclear training. By the year 2000, for an installed nuclear capacity of 150 to 200 GW, overall manpower requirements should increase to more than 500,000 which would include 130,000 with specialized nuclear training. (author)
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Education and Rural Development with Reference to Developing Countries.
Coverdale, G.M.
Seeking full use of the educational resources available to developing countries in the areas of rural education and agricultural training, this paper is concerned with ways in which the efforts of organizations and institutions concerned with rural development might be improved and expanded. A generalized critical analysis of different facets of…
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Infection control in developing countries.
Meers, P D
1988-02-01
The level of socio-political and economic development achieved by a country determines the quality and quantity of the health care its citizens receive. These factors also govern the amount of attention given to hospital-acquired infection. The problems of infection control in 'developing' countries include, first, the international problems that arise from clashes of personality and viewpoint among those responsible for it, exacerbated in some places by ethnic or religious traditions. Second are problems imposed by factors that affect the spectrum of infectious disease, and third is a variable deficiency of human and financial resources. In the search for solutions, an analysis suggests that nurses are particularly suited to take the lead in the prevention of infection, so that a special initiative directed towards their education in the rapidly developing science of hospital infection and its control is likely to be the most cost effective and appropriate initial approach. This needs to be accompanied by parallel improvements in the education of medical undergraduates. Anything else should be applied in response to measured need, and then only as money and manpower permit. Careful thought is required to avoid squandering scarce resources by applying inappropriate infection control technology.
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Pediatric anesthesia in developing countries.
Bösenberg, Adrian T
2007-06-01
To highlight the problems faced in developing countries where healthcare resources are limited, with particular emphasis on pediatric anesthesia. The fact that very few publications address pediatric anesthesia in the developing world is not surprising given that most anesthetics are provided by nonphysicians, nurses or unqualified personnel. In compiling this article information is drawn from pediatric surgical, anesthetic and related texts. In a recent survey more than 80% of anesthesia providers in a poor country acknowledged that with the limited resources available they could not provide basic anesthesia for children less than 5 years. Although many publications could be regarded as anecdotal, the similarities to this survey suggest that the lack of facilities is more generalized than we would like to believe. The real risk of anesthesia in comparison to other major health risks such as human immunodeficiency virus, malaria, tuberculosis and trauma remains undetermined. The critical shortage of manpower remains a barrier to progress. Despite erratic electrical supplies, inconsistent oxygen delivery, paucity of drugs or equipment and on occasion even lack of running water, many provide life-saving anesthesia. Perioperative morbidity and mortality is, however, understandably high by developed world standards.
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International Nuclear Information System (INIS)
Ward, D S; Mahowald, N M
2014-01-01
Understanding the relative contributions of individual countries to global climate change for different time periods is essential for mitigation strategies that seek to hold nations accountable for their historical emissions. Previous assessments of this kind have compared countries by their greenhouse gas emissions, but have yet to consider the full spectrum of the short-lived gases and aerosols. In this study, we use the radiative forcing of anthropogenic emissions of long-lived greenhouse gases, ozone precursors, aerosols, and from albedo changes from land cover change together with a simple climate model to evaluate country contributions to climate change. We assess the historical contribution of each country to global surface temperature change from anthropogenic forcing ( Δ T s ), future Δ T s through year 2100 given two different emissions scenarios, and the Δ T s that each country has committed to from past activities between 1850 and 2010 (committed Δ T s ). By including forcings in addition to the long-lived greenhouse gases the contribution of developed countries, particularly the United States, to Δ T s from 1850 to 2010 (58%) is increased compared to an assessment of CO 2 -equivalent emissions for the same time period (52%). Contributions to committed Δ T s evaluated at year 2100, dominated by long-lived greenhouse gas forcing, are more evenly split between developed and developing countries (55% and 45%, respectively). The portion of anthropogenic Δ T s attributable to developing countries is increasing, led by emissions from China and India, and we estimate that this will surpass the contribution from developed countries around year 2030. (paper)
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Marques, Andrea Horvath; Bjørke-Monsen, Anne-Lise; Teixeira, Antônio L; Silverman, Marni N
2015-08-18
Evidence suggests that maternal and fetal immune dysfunction may impact fetal brain development and could play a role in neurodevelopmental disorders, although the definitive pathophysiological mechanisms are still not completely understood. Stress, malnutrition and physical inactivity are three maternal behavioral lifestyle factors that can influence immune and central nervous system (CNS) functions in both the mother and fetus, and may therefore, increase risk for neurodevelopmental/psychiatric disorders. First, we will briefly review some aspects of maternal-fetal immune system interactions and development of immune tolerance. Second, we will discuss the bidirectional communication between the immune system and CNS and the pathways by which immune dysfunction could contribute to neurodevelopmental disorders. Third, we will discuss the effects of prenatal stress and malnutrition (over and undernutrition) on perinatal programming of the CNS and immune system, and how this might influence neurodevelopment. Finally, we will discuss the beneficial impact of physical fitness during pregnancy on the maternal-fetal unit and infant and how regular physical activity and exercise can be an effective buffer against stress- and inflammatory-related disorders. Although regular physical activity has been shown to promote neuroplasticity and an anti-inflammatory state in the adult, there is a paucity of studies evaluating its impact on CNS and immune function during pregnancy. Implementing stress reduction, proper nutrition and ample physical activity during pregnancy and the childbearing period may be an efficient strategy to counteract the impact of maternal stress and malnutrition/obesity on the developing fetus. Such behavioral interventions could have an impact on early development of the CNS and immune system and contribute to the prevention of neurodevelopmental and psychiatric disorders. Further research is needed to elucidate this relationship and the underlying
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Grid and Cloud for Developing Countries
Petitdidier, Monique
2014-05-01
The European Grid e-infrastructure has shown the capacity to connect geographically distributed heterogeneous compute resources in a secure way taking advantages of a robust and fast REN (Research and Education Network). In many countries like in Africa the first step has been to implement a REN and regional organizations like Ubuntunet, WACREN or ASREN to coordinate the development, improvement of the network and its interconnection. The Internet connections are still exploding in those countries. The second step has been to fill up compute needs of the scientists. Even if many of them have their own multi-core or not laptops for more and more applications it is not enough because they have to face intensive computing due to the large amount of data to be processed and/or complex codes. So far one solution has been to go abroad in Europe or in America to run large applications or not to participate to international communities. The Grid is very attractive to connect geographically-distributed heterogeneous resources, aggregate new ones and create new sites on the REN with a secure access. All the users have the same servicers even if they have no resources in their institute. With faster and more robust internet they will be able to take advantage of the European Grid. There are different initiatives to provide resources and training like UNESCO/HP Brain Gain initiative, EUMEDGrid, ..Nowadays Cloud becomes very attractive and they start to be developed in some countries. In this talk challenges for those countries to implement such e-infrastructures, to develop in parallel scientific and technical research and education in the new technologies will be presented illustrated by examples.
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Professional development for nuclear power programs in developing countries
International Nuclear Information System (INIS)
Kanter, M.A.
1983-01-01
Countries entering nuclear power programs for the first time find that inadequate planning for the development of trained manpower is a critical factor in the success of their programs. This requires the early training of a team for the planning and acquisition effort to be followed by training for the supervision of construction. In addition, there is the more readily recognized training for operation. Typical manpower needs for such projects have been documented by the International Atomic Energy Agency. The basic academic training of engineers and scientists, which should be available within the country; advanced academic training, which is often secured in institutions abroad; specialized training abroad by international agencies; specialized training by the vendors of nuclear equipment; and the development of indigenous training. This paper outlines all of these avenues but will concentrate on the training available through international agencies and on the development of indigenous training capability
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Causes of childhood blindness in a developing country and an underdeveloped country.
Santos-Bueso, E; Dorronzoro-Ramírez, E; Gegúndez-Fernández, J A; Vinuesa-Silva, J M; Vinuesa-Silva, I; García-Sánchez, J
2015-05-01
The causes of childhood blindness depend on factors such as geographic location or the human development index of the populations under study. The main causes in developed countries are genetic and hereditary diseases, while infectious and contagious diseases, together with nutritional and vitamin deficiencies, are the main causes in underdeveloped countries (UDCs). Study of the causes of blindness among children admitted to a regional centre in Nador, Morocco, and among children in Mekele, Ethiopia. The study was carried out in collaboration with two non-governmental organizations based in Madrid, Spain. First, we worked with Fudación Adelias in June 2010, and with Proyecto Visión in October 2012. The study comprised a total of 27 children in Morocco and 85 in Ethiopia. The average age of the children was 10.92 and 6.94 years, respectively. The main causes of blindness in Morocco were hereditary pathologies (25.92%) and refractive errors (14.82%), although trauma (7.40%) and corneal disease (7.40%) are relevant. Among the children from Ethiopia, corneal disease (27.05%) and trauma (20%) were the main causes of blindness, while congenital and hereditary diseases had a lower prevalence (4.70%). The causes of blindness depend on the human development index of the populations under study. While corneal disease and trauma are the main causes observed in UDCs like Ethiopia, hereditary pathologies and refractive errors are the main causes within the Moroccan population studied. A mixed form can be observed in this country, as the cause of blindness found in developed countries, such as congenital and hereditary pathologies which are present alongside the causes normally found in LDCs. Copyright © 2015 Elsevier Masson SAS. All rights reserved.
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Directory of Open Access Journals (Sweden)
Yenni Viviana Duque Orozco
2012-12-01
Full Text Available International business research has considered the Corporate Social Responsibility (CSR of the Multinational Enterprises (MNEs and so Multilateral Organizations have developed different recommendations about what these companies should do in different social areas, especially in labor practices. MNEs play a significant role given their influence and activities in both home and host countries. They play a double role: actor of the problem, but also the actor of the solution. The purpose of the paper is to identify the differences of Socially Responsible Practices (SRP between MNEs from developed countries and MNEs from developing countries in Colombia. The method used in this document is a literature review from several academic databases; and we check CSR programs published in Web sites in the host country (Colombia of six MNE´s The results suggest that Multinationals from developing countries focus their practices on the community, mainly in education programs, while Multinationals from developed countries try to work with all stakeholders and involve particularly aspects related with their business in the programs they develop. This is possible because MNEs from developed countries use better divulgation mechanisms. SRP less mentioned in both cases are related to employees. Commitment with ethical responsibilities, promote greater economic and social inclusion should be the goals for MNEs in developing countries. In the other hand, the government has to play a more important role in this ground establishing minimum standards for MNEs that want to operate in developing countries, and some education programs to sensitize society into a more responsible consumption, in order to generate social pressure.
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Construction industry in developing countries
Energy Technology Data Exchange (ETDEWEB)
Moavenzadeh, F
1978-01-01
This paper provides a review of the construction capability available in the developing countries to meet the demand for shelter. It discusses the role of construction in the process of development and its importance to economic growth. It considers the issue facing the growth of a viable indigenous construction industry in the developing world within the context of the activities involved in the creation of constructed facilities--planning, design, contruction and maintenance; it also examines the environment within which the industry has developed. For each construction activity the paper reviews available capabilities, the various resources needed for the development of an indigenous industry, and some possible means of accommodating these needs.
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Comparative Characteristics of Technology Transfer in Developed Countries
Directory of Open Access Journals (Sweden)
Natalia Palii
2013-08-01
Full Text Available The research into innovation transfer in the global economy is a very urgent issue under the modern conditions of development of any country. Comparative characteristics of technology transfer in such countries and regions as the USA, EU, Asia, presented in the article, permit us to detect certain patterns of this process inherent both in developed and developing countries. The analysis made in the article can be useful for developing technology transfer processes in the Danube countries’ economy. The analytical method used in this research allowed us to determine the factor that is crucial for the growth of the world market of high-technology products and services. The analysis was conducted on several criteria such as the level of expenditure on R&D in the whole global economy, as well as in individual countries and regions. Besides, there were taken into account the added value of high-tech industries and the share of expenditure on R&D in total production costs. The conclusions regarding the effectiveness of funds allocated for scientific research and experimental development in the U.S. can be drawn on the basis of data presented in the paper on the amount of added value of the U.S. high-tech industries.
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Test development and use in five Iberian Latin American countries.
Wechsler, Solange M; Oakland, Thomas; León, Carmem; Vivas, Eleonora; de Almeida, Leandro; Franco, Amanda; Pérez-Solís, María; Contini, Norma
2014-08-01
The abundance of scholarship on test development and use generally is higher in English-speaking than in Iberian Latin American countries. The purpose of this article is to help overcome this imbalance by describing and identifying similarities and differences in test development and use in two Iberian (Portugal and Spain) and three of the largest Latin American (Argentina, Brazil, and Venezuela) countries. The stages of test development in each country, roles of professional associations, presence of standards for test use, professionals' educational training, commonly used tests, together with prominent challenges to continued progress are discussed. Test development and use in these five countries are transitioning from a dependence on the use of translated tests to greater reliance on adapted and finally nationally constructed tests. Continued growth requires adherence to international standards guiding test development and use. Stronger alliance among professional associations in the Iberian Latin American countries could serve as a catalyst to promote test development in these regions. © 2014 International Union of Psychological Science.
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Report on WHO meeting on immunization in older adults: Geneva, Switzerland, 22-23 March 2017.
Teresa Aguado, M; Barratt, Jane; Beard, John R; Blomberg, Bonnie B; Chen, Wilbur H; Hickling, Julian; Hyde, Terri B; Jit, Mark; Jones, Rebecca; Poland, Gregory A; Friede, Martin; Ortiz, Justin R
2018-02-08
Many industrialized countries have implemented routine immunization policies for older adults, but similar strategies have not been widely implemented in low- and middle-income countries (LMICs). In March 2017, the World Health Organization (WHO) convened a meeting to identify policies and activities to promote access to vaccination of older adults, specifically in LMICs. Participants included academic and industry researchers, funders, civil society organizations, implementers of global health interventions, and stakeholders from developing countries with adult immunization needs. These experts reviewed vaccine performance in older adults, the anticipated impact of adult vaccination programs, and the challenges and opportunities of building or strengthening an adult and older adult immunization platforms. Key conclusions of the meeting were that there is a need for discussion of new opportunities for vaccination of all adults as well as for vaccination of older adults, as reflected in the recent shift by WHO to a life-course approach to immunization; that immunization in adults should be viewed in the context of a much broader model based on an individual's abilities rather than chronological age; and that immunization beyond infancy is a global priority that can be successfully integrated with other interventions to promote healthy ageing. As WHO is looking ahead to a global Decade of Healthy Ageing starting in 2020, it will seek to define a roadmap for interdisciplinary collaborations to integrate immunization with improving access to preventive and other healthcare interventions for adults worldwide. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.
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Batt, Katherine; Fox-Rushby, J A; Castillo-Riquelme, Marianela
2004-09-01
Evidence-based reviews of published literature can be subject to several biases. Grey literature, however, can be of poor quality and expensive to access. Effective search strategies also vary by topic and are rarely known in advance. This paper complements a systematic review of the published literature on the costs and effects of expanding immunization services in developing countries. The quality of data on the effectiveness and cost-effectiveness of strategies to increase immunization coverage is shown to be similar across literatures, but the quality of information on costing is much lower in the grey literature. After excluding poorer quality studies from this review we found the quantity of available evidence almost doubled, particularly for more complex health-system interventions and cost or cost-effectiveness analyses. Interventions in the grey literature are more up to date and cover a different geographical spread. Consequently the conclusions of the published and grey literatures differ, although the number of papers is still too low to account for differences across types of interventions. We recommend that in future researchers consider using non-English keywords in their searches.
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Radiation disinfestation: A viable technology for developing countries
International Nuclear Information System (INIS)
Loaharanu, P.
1985-01-01
Increasing food production in many countries is often offset by spoilage losses that occur at different stages after harvesting, slaughtering, or catching. The situation becomes critical in developing countries as more food is needed to feed the ever-increasing population. One of the major problems of losses of food and agricultural products during storage is insect infestation. This paper reviews some insect infestation problems of valuable crops in developing countries such as cereals, pulses, dried fish and meat, fresh and dried fruits, coffee and cocoa beans, spices, and cured tobacco leaves. Present practices of chemical fumigation to eliminate insect problems in these crops give rise to concern from the points of view of both public health and occupational safety. Irradiation technology has been shown to be as effective as other insect disinfestation methods and could provide a viable alternative for this purpose. Insects do not develop resistance to physical techniques such as heat or irradiation as they do to chemical treatments. Applications of radiation for disinfestation of food and agricultural products of importance to developing countries are discussed. The economics of radiation disinfestation of cereals and pulses, dried fish, and fresh fruits are also discussed
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Reprocessing considerations for a developing country
International Nuclear Information System (INIS)
This paper describes some of the alternatives for dealing with spent fuel that face a developing country. It then discusses the considerations that affect decisions on the size and siting of reprocessing plants, and shows how small plants may be suitable in countries without the means to transport spent fuel easily. The paper also outlines the reasons for reprocessing in India, and describes the development of India's reprocessing capability. It shows how the economic conditions in India, such as low skilled labour costs, make reprocessing plants of 100 to 200 tonnes U/yr capacity economic, and includes a table giving technical data on a 100 t U/yr national plant for inclusion in the reference cases used by INFCE Working Group 4
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Teaching of Psychology in Countries with Advanced versus Developing Economies
Pinquart, Martin; Bernardo, Allan B. I.
2014-01-01
We compare structures and contents of psychology programmes from countries with developing and advanced economies. Respondents from 49 countries completed a survey of the International Union of Psychological Science on psychology education and training. In general, there are more similarities than differences between countries with developing and…
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Nuclear power for developing countries
International Nuclear Information System (INIS)
Hirschmann, H.; Vennemann, J.
1980-01-01
The paper describes the energy policy quandary of developing countries and explains why nuclear power plants of a suitable size - the KKW 200 MW BWR nuclear power plant for electric power and/or process steam generation is briefly presented here - have an economic advantage over fossil-fuelled power plants. (HP) [de
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Energy and environmental consciousness. Differences between advanced and developing countries
International Nuclear Information System (INIS)
Takeshita, Takashi
1999-01-01
The purpose of the present study is to understand how much differences there are between advanced countries and developing countries in terms of environmental and energy consciousness. We are experiencing now a big dilemma of the human desire to continue to exist and, at the same time, to develop the economy against the worsening of the Earth's environmental conditions. Understanding international differences of environmental and energy consciousness is a short way to solve this dilemma. The results of the present study were that peoples from advanced countries feel that science and technology are sometimes unreliable, while those from developing countries, are willing to rely upon them. However regardless of the country, people share the same consciousness about Earth's environment. In both, advanced and developing countries, people are reluctant to give up living comforts, unless this leads to a higher standard of living. Based on this result, the author would like to conduct another survey concerning the consciousness of future lifestyle. (author)
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Information-communication technology impact on labor productivity growth of EU developing countries
Directory of Open Access Journals (Sweden)
Ljiljana Lovrić
2012-12-01
Full Text Available The aim of this study is to investigate the ICT impact on labor productivity growth of EU developing countries. Empirical studies of the role of ICT as one of the main determinants of productivity growth, for developing countries have produced disagreement. To help clear up the subject, this paper employs a Generalized Method of Moments (GMM through a dynamic panel data approach on the sample of 25 European developed and developing countries over the period of 2001-2010. The results indicate a positive and significant impact of ICT on labor productivity growth in developed and developing countries, but the terms of impact in developing countries rely on human capital, a contribution of a higher educational level, advanced research qualifications and development activity. Comparing to developed countries, the growth accounting approach indicate that developing countries have similar relative ICT contribution to labor productivity growth, but their average growth rate of labor productivity is 6.8 times higher. The main conclusion is that education, especially of higher levels, is the critical factor of productivity and growth of EU developing countries and that must be taken as development policy implication in these countries.
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Technology transfer of nuclear power development in developing countries: Case study of China
International Nuclear Information System (INIS)
He Jiachen; Shen Wenquan; Zhang Luqing
2000-01-01
This paper describes the specific experiences in the technology transfer of nuclear power in China, a country that both imported and developed indigenous nuclear technology. Based on this experience some recommendations are presented that should be considered particularly by the developing countries. (author)
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Climate change mitigation in the energy sector of developing countries
International Nuclear Information System (INIS)
Sathaye, J.A.
1998-01-01
The Framework Convention on Climate change, singed by more than 150 governments worldwide, calls on parties to the Convention to undertake inventories of national sources and sinks of greenhouse gases and to develop plans for responding to climate change. Several institutions, including UNEP, have initiated programs to assist developing countries and countries with economies in transition to meet this obligation. This paper describes a mitigation methodology that is being used for these country studies, and discusses issues that have arisen in conducting mitigation assessments for developing countries in the past. (EG)
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Developing countries' motivation to use nuclear technology
International Nuclear Information System (INIS)
Ratsch, U.
1990-01-01
Governments of various developing countries see nuclear energy as an important tool for at least three political goals: Firstly, the expected rise in future energy demand, so they argue, can only be met if nuclear electricity production in the Third World is expanded. Fossil sources are supposed to become increasingly scarce and expensive, and they are also seen to be ecologically damaging. Technologies to harness renewable energy sources are not yet mature and still too costly. Secondly, nuclear technology is seen as one of the most advanced technologies. Mastering of it might help to diminish the technological gap between the First and the Third World. Thirdly, scientific progress in developing countries is hoped to be accelerated by operating research reactors in these countries. All of these arguments ought to be taken as serious motivations. (orig./HSCH) [de
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China and the Manufacturing Exports of Other Developing Countries
Gordon H. Hanson; Raymond Robertson
2008-01-01
In this paper, we examine the impact of China's growth on developing countries that specialize in manufacturing. Over 2000-2005, manufacturing accounted for 32% of China's GDP and 89% of its merchandise exports, making it more specialized in the sector than any other large developing economy. Using the gravity model of trade, we decompose bilateral trade into components associated with demand conditions in importing countries, supply conditions in exporting countries, and bilateral trade cost...
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Directory of Open Access Journals (Sweden)
X Yang
1998-01-01
Full Text Available Chlamydia trachomatis is an obligate intracellular bacterial pathogen that causes several significant human infectious diseases, including trachoma, urethritis, cervicitis and salpingitis, and is an important cofactor for transmission of human immunodeficiency virus. Until very recently, over three decades of research effort aimed at developing a C trachomatis vaccine had failed, due mainly to the lack of a precise understanding of the mechanisms for protective immunity. Although most studies concerning protective immunity to C trachomatis have focused on humoral immune responses, recent studies have clearly shown that T helper-1 (Th1-like CD4 T cell-mediated immune responses play the dominant role in protective immunity. These studies suggest a paradigm for chlamydial immunity and pathology based on the concept of heterogeneity (Th1/Th2 in CD4 T cell immune responses. This concept for chlamydial immunity offers a rational template on which to base renewed efforts for development of a chlamydial vaccine that targets the induction of cell-mediated Th1 immune responses.
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Rearing environment affects development of the immune system in neonates
Inman, C.F.; Haverson, K.; Konstantinov, S.R.; Jones, P.H.; Harris, C.; Smidt, H.; Miller, B.; Bailey, M.; Stokes, C.
2010-01-01
P>Early-life exposure to appropriate microbial flora drives expansion and development of an efficient immune system. Aberrant development results in increased likelihood of allergic disease or increased susceptibility to infection. Thus, factors affecting microbial colonization may also affect
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ALLERGIC ASTHMA AND THE DEVELOPING IMMUNE SYSTEM: A PILOT STUDY
Rationale: The predisposition towards atopic disease begins early in life, and that the risk of developing asthma is heightened following prenatal exposure to some compounds. Nonetheless, the effect of gestational aeroallergen exposure on the developing immune system is unclear....
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Counterfeit drugs and medical devices in developing countries
Directory of Open Access Journals (Sweden)
Glass BD
2014-03-01
Full Text Available Beverley D GlassSchool of Pharmacy and Molecular Sciences, James Cook University, Townsville, QLD, AustraliaAbstract: The World Health Organization has reported that counterfeit medicines potentially make up more than 50% of the global drug market, with a significant proportion of these fake products being encountered in developing countries. This occurrence is attributed to a lack of effective regulation and a weak enforcement capacity existing in these countries, with an increase in this trade resulting from the growing size and sophistication of drug counterfeiters. In addition, due to both cost and lack of availability of medicines, consumers in developing countries are more likely to seek out these inexpensive options. The World Health Organization is mindful of the impact of counterfeit drugs on consumer confidence in health care systems, health professionals, the supply chain, and genuine suppliers of medicines and medical devices. Antibiotics, antituberculosis drugs, and antimalarial and antiretroviral drugs are frequently targeted, with reports of 60% of the anti-infective drugs in Asia and Africa containing active pharmaceutical ingredients outside their pharmacopoeial limits. This has obvious public health implications of increasing drug resistance and negating all the efforts that have already gone into the provision of medicines to treat these life threatening conditions in the developing world. This review, while focusing on counterfeit medicines and medical devices in developing countries, will present information on their impact and how these issues can be addressed by regulation and control of the supply chain using technology appropriate to the developing world. The complexity of the problem will also be highlighted in terms of the definition of counterfeit and substandard medicines, including gray pharmaceuticals. Although this issue presents as a global public health problem, outcomes in developing countries where counterfeit
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Physical Environment Correlates of Physical Activity in Developing Countries: A Review.
Day, Kristen
2018-04-01
Noncommunicable diseases and obesity are considered problems of wealthy, developed countries. These conditions are rising dramatically in developing countries. Most existing research on the role of the physical environment to support physical activity examines developed countries only. This review identifies physical environment factors that are associated with physical activity in developing countries. This review is modeled on a highly cited review by Saelens and Handy in 2008. The current review analyzes findings from 159 empirical studies in the 138 developing countries. Results discuss the association of physical environment features and physical activity for all developing countries and identify the patterns within regions. The review supports the association of traffic safety with physical activity for transportation. Rural (vs urban) residence, distance to nonresidential land uses, and "composite" features of the physical environment are associated with general physical activity. Rural (vs urban) residence is associated with physical activity for work. More research is needed on associations between the physical environment and physical activity in developing countries. Research should identify specific physical environment features in urban areas that are associated with higher activity levels.
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Universal varicella vaccine immunization in Japan.
Yoshikawa, Tetsushi; Kawamura, Yoshiki; Ohashi, Masahiro
2016-04-07
In 1974, Japanese scientists developed a live attenuated varicella vaccine based on the Oka strain. The efficacy of the vaccine for the prevention of varicella has been primarily demonstrated in studies conducted in the United States following the adoption of universal immunization using the Oka strain varicella vaccine in 1996. Although the vaccine was developed by Japanese scientists, until recently, the vaccine has been administered on a voluntary basis in Japan resulting in a vaccine coverage rate of approximately 40%. Therefore, Japan initiated universal immunization using the Oka strain varicella vaccine in November 2014. Given the transition from voluntary to universal immunization in Japan, it will also be important to monitor the epidemiology of varicella and herpes zoster. The efficacy and safety of co-administration of the varicella vaccine and measles, mumps, and rubella vaccine have been demonstrated in many countries; however, there was no data from Japan. In order to adopt the practice of universal immunization using the Oka strain varicella vaccine in Japan, data demonstrating the efficacy and safety of co-administration of varicella vaccine and measles and rubella (MR) vaccine were required. Additionally, we needed to elucidate the appropriate time interval between the first and second administrations of the vaccine. It is also important to differentiate between wild type and Oka vaccine type strains in herpes zoster patient with past history of varicella vaccine. Thus, there are many factors to consider regarding the adoption of universal immunization in Japan to control varicella zoster virus (VZV) infections. Copyright © 2016 Elsevier Ltd. All rights reserved.
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Maintenance of nuclear medicine instruments in developing countries
International Nuclear Information System (INIS)
1976-01-01
This report reviews the current nature and severity of the problems related to nuclear medicine instruments in developing countries and gives the recommendations of the Advisory Group on the development of improved strategies to assure that the instruments are effectively maintained while in use. A compilation of data from the Register of Medical Radioisotope Units (IAEA-167) on medical radioisotope instrumentation installed in developing countries and some comments and suggestions contained in reports of Agency Technical Assistance Experts are also presented
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DEFF Research Database (Denmark)
Adjin, Daniel Michael Okwabi; Tadayoni, Reza; Tsivor, Kenneth
2013-01-01
. There are bundles of drivers for developing and deploying ITS solutions for technological advancement and societal modernization, as well as economic growth and sustainability for developing countries. Ironically, there also exit a number of barriers mitigating the development and deployment of ITS technologies...... in these countries. The main bottlenecks to deploying ITS applications in developing countries include: insufficient understanding of the potentials of ITS and its benefits due to lack of education and awareness, lack of financial resources, lack of technical support, difficulties in integrating ITS applications...
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Globalization, democracy, and child health in developing countries.
Welander, Anna; Lyttkens, Carl Hampus; Nilsson, Therese
2015-07-01
Good health is crucial for human and economic development. In particular poor health in childhood is of utmost concern since it causes irreversible damage and has implications later in life. Recent research suggests globalization is a strong force affecting adult and child health outcomes. Yet, there is much unexplained variation with respect to the globalization effect on child health, in particular in low- and middle-income countries. One factor that could explain such variation across countries is the quality of democracy. Using panel data for 70 developing countries between 1970 and 2009 this paper disentangles the relationship between globalization, democracy, and child health. Specifically the paper examines how globalization and a country's democratic status and historical experience with democracy, respectively, affect infant mortality. In line with previous research, results suggest that globalization reduces infant mortality and that the level of democracy in a country generally improves child health outcomes. Additionally, democracy matters for the size of the globalization effect on child health. If for example Côte d'Ivoire had been a democracy in the 2000-2009 period, this effect would translate into 1200 fewer infant deaths in an average year compared to the situation without democracy. We also find that nutrition is the most important mediator in the relationship. To conclude, globalization and democracy together associate with better child health in developing countries. Copyright © 2015 Elsevier Ltd. All rights reserved.
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Expedited patent examination for green inventions: Developing countries' policy choices
International Nuclear Information System (INIS)
Lu, Bingbin
2013-01-01
Innovation in green technology is important. Patent rights can provide incentives for green technology research and development. Expedited patent examination for green inventions has emerged as a policy instrument to provide such incentives. Developing countries were never opposed to patents for green technologies. China and Brazil have led the way by offering expedited examinations for green patent applications. More developing countries are expected to follow. Expedited examination for green technologies is consistent with the intellectual property system objectives and is justified by the clear social benefit from green technologies. Introducing such expedited programs in developing countries has sufficient advantages. Existing models of expedited programs for green technologies are analyzed to generalize key issues and to discern suitable policy choices for developing countries. When introducing such programs, a balanced definition for green technology is preferred; a special classification requirement is premature and is not recommended; a pre-examination search requirement is generally recommended to balance patent office workloads, and a green patent database is recommended. - Highlights: • There is no north–south divide in promoting green technologies. • Earlier issuance of green patents has its great social benefit. • Green patent application should receive expedited examination. • Developing countries should introduce such expedited programs. • A suitable approach for developing countries is searched and recommended
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Developing countries: small technology with big effects
International Nuclear Information System (INIS)
McRobie, G.; Carr, M.
1978-01-01
As far the poor countries of the world are concerned, during the past twenty years they have had access only to the technologies developed by the rich to suit the rich. It is now beyond question that some of the most daunting problems confronting the majority of the worlds populations stem directly from the kind of technology transferred to them under current aid and development programs. That the technology of the rich is generally inappropriate to meet the needs and resources of the poor countries is becoming more widley recognized both by aid-givers and aid-receivers. Yet it is this technology that continues to be almost exclusively and most powerfully promoted in the developing countries. To meet their needs a new technology must be discovered or devised: one that lies between the sickle and the combine harvester and is small, simple and cheap enough to harmonise withlocal human and material resources and lends itself to widespread reproduction with the minimum of outside help. What we now need most urgently is a new set of technologies, designed, by people who are informed by the need to develop capital-saving technologies capable of being decentralized to the maximum extend. The technology gap is not only wide, but the knowledge an resources required to fill is, although they exist in the industrialized countries, have not been mobilized to provide the right kind of knowledge and to make it available to those who need it. It was to do this that the Intermediate Technology Development Group was set up ten years ago. (orig.) 891 HP 892 EKI [de
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Development and function of human innate immune cells in a humanized mouse model.
Rongvaux, Anthony; Willinger, Tim; Martinek, Jan; Strowig, Till; Gearty, Sofia V; Teichmann, Lino L; Saito, Yasuyuki; Marches, Florentina; Halene, Stephanie; Palucka, A Karolina; Manz, Markus G; Flavell, Richard A
2014-04-01
Mice repopulated with human hematopoietic cells are a powerful tool for the study of human hematopoiesis and immune function in vivo. However, existing humanized mouse models cannot support development of human innate immune cells, including myeloid cells and natural killer (NK) cells. Here we describe two mouse strains called MITRG and MISTRG, in which human versions of four genes encoding cytokines important for innate immune cell development are knocked into their respective mouse loci. The human cytokines support the development and function of monocytes, macrophages and NK cells derived from human fetal liver or adult CD34(+) progenitor cells injected into the mice. Human macrophages infiltrated a human tumor xenograft in MITRG and MISTRG mice in a manner resembling that observed in tumors obtained from human patients. This humanized mouse model may be used to model the human immune system in scenarios of health and pathology, and may enable evaluation of therapeutic candidates in an in vivo setting relevant to human physiology.
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University role in nuclear power program in developing countries
International Nuclear Information System (INIS)
Notea, A.
1977-01-01
The academic education in nuclear engineering should be considered as a subsystem within the general nuclear program of the country as well as within the educational structure of the university. The academic trained personnel are of major importance as future participants in decisional and planning steps of the program. Hence, the ''production'' of academic manpower in this field should be started at the earliest steps. The nuclear engineering curriculum should be planned in accordance with the objectives stated by the power program and the challenges foreseen. Obviously, the objectives in a developing country are considerably different from those of developed countries highly advanced in the nuclear power field. The paper analyzes possible objectives in a developing country which intends to implement nuclear power program. In view of these objectives curricula planning for the undergraduate and graduate levels are presented and explained. The courses for undergraduates intend to provide basic information to relatively large numbers of students from various faculties, as they are expected to join the program at various constructional stages. Major emphasise is given to graduates as they will act in the cadre of senior engineers and officials of the country. The research works for theses in developed countries may be highly technical, dealing with crumbs of huge development project carried out on national or international level. Such research works are hardly justified in countries not involved in the project. In developing countries the problems to be confronted with are mainly licensing and siting and to much less extent nuclear power technology. Hence the choice of subjects for theses should be coherent with these directions. Obviously, the subjects are bound to the department manpower and budgetary limitations. As a demonstration two fields were analysed under our local constraints and objectives. Subjects suitable for theses are pointed out. The fields dealt
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Establishing molecular microbiology facilities in developing countries
Directory of Open Access Journals (Sweden)
Salman S. Ahmed
2015-11-01
Full Text Available Summary: Microbiology laboratories play an important role in epidemiology and infection control programs. Within microbiology laboratories, molecular microbiology techniques have revolutionized the identification and surveillance of infectious diseases. The combination of excellent sensitivity, specificity, low contamination levels and speed has made molecular techniques appealing methods for the diagnosis of many infectious diseases. In a well-equipped microbiology laboratory, the facility designated for molecular techniques remains indiscrete. However, in most developing countries, poor infrastructure and laboratory mismanagement have precipitated hazardous consequences. The establishment of a molecular microbiology facility within a microbiology laboratory remains fragmented. A high-quality laboratory should include both conventional microbiology methods and molecular microbiology techniques for exceptional performance. Furthermore, it should include appropriate laboratory administration, a well-designed facility, laboratory procedure standardization, a waste management system, a code of practice, equipment installation and laboratory personnel training. This manuscript lays out fundamental issues that need to be addressed when establishing a molecular microbiology facility in developing countries. Keywords: Developing country, Molecular technique, Molecular microbiology laboratory
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The domestic natural gas industry in developing countries
International Nuclear Information System (INIS)
Klass, D.L.; Khan, R.A.; Khwaja, S.
1992-01-01
The domestic natural gas industry has generally exhibited slow growth in most developing countries that are fortunate enough to have sufficient proved gas reserves to meet energy needs. But supportive government policies that promote the use of indigenous reserves are now beginning to have a positive impact in many parts of the world. Supply and distribution infrastructures are being built or modernized. And natural gas is now or will be available at prices that encourage the displacement of competitive fuels in the larger, energy-intensive industrial and power-generation markets of these countries. It is expected that the domestic gas industry in many developing countries will expand at higher rates than in the past. In the next few decades, the resulting benefits will include reductions in oil consumption per capita, improvements in the balance of payments for oil-importing and exporting developing countries, greater efficiency of energy usage and lower energy consumption per output unit, and improved environmental quality. The national economies and living standards will also undergo significant advancement
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Shetty, P; Schmidhuber, J
2006-07-01
Obesity is recognized as a serious problem in the industrialized and developed countries of the world. However, little attention is paid to the fact that obesity is becoming an increasing problem in developing countries too, with some countries showing increasing rates of obesity in the midst of the persisting occurrence of childhood malnutrition and stunting. As developing countries embrace the dominant western economic ways of development, industrialization and urbanization they contribute to improvements in living standards, with consequent dramatic changes in diets and lifestyles leading to weight gain and obesity which in turn poses a growing threat to the health. Overweight and obesity is associated with an increased likelihood of non-insulin dependent diabetes mellitus, hypertension, hyper-lipidaemia, and cardiovascular disease. It is also associated with increased rates of breast, colo-rectal and uterine cancer. Obesity is thus an important factor in the increasing morbidity and mortality due to chronic, non-communicable diseases (NCDs) and thereby contributes to premature mortality in the population. Thus, while the problem of undernutrition persists in much of the developing world, overweight and obesity and its related co-morbidities are posing an increasingly important public health problem both in the developed and developing world.
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Limited resources of genome sequencing in developing countries: Challenges and solutions
Directory of Open Access Journals (Sweden)
Mohamed Helmy
2016-06-01
Full Text Available The differences between countries in national income, growth, human development and many other factors are used to classify countries into developed and developing countries. There are several classification systems that use different sets of measures and criteria. The most common classifications are the United Nations (UN and the World Bank (WB systems. The UN classification system uses the UN Human Development Index (HDI, an indicator that uses statistic of life expectancy, education, and income per capita for countries' classification. While the WB system uses gross national income (GNI per capita that is calculated using the World Bank Atlas method. According to the UN and WB classification systems, there are 151 and 134 developing countries, respectively, with 89% overlap between the two systems. Developing countries have limited human development, and limited expenditure in education and research, among several other limitations. The biggest challenge facing genomic researchers and clinicians is limited resources. As a result, genomic tools, specifically genome sequencing technologies, which are rapidly becoming indispensable, are not widely available. In this report, we explore the current status of sequencing technologies in developing countries, describe the associated challenges and emphasize potential solutions.
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Lending Groups and Different Social Capitals in Developed and Developing Countries
Directory of Open Access Journals (Sweden)
Diego A. B. Marconatto
2016-11-01
Full Text Available Lending groups (LGs and social capital are two central elements to the many microfinance solutions operating around the world. However, LG effectiveness in reducing transaction costs and lending risks for microfinance institutions (MFIs is mediated by institutional environments. Starting from this assumption, we discuss the existent interactions between the institutional environments of developed (Anglo-Saxon and communitarian and developing countries with different stocks of social capital (individual, network and institutional and the influences of this interaction on LG effectiveness. In order to do so, we applied the institutional perspective of O. Williamson to build a theoretical framework to examine the interaction of all these conditions, allowing for analysis of their main relations within the microfinance context. Based on this framework, we propose on the one hand that in developing and Anglo-Saxon developed nations, stocks of both individual and network social capital are the most important for an LG’s effectiveness. However, in Anglo-Saxon countries, these two stocks of social capital are complemented by formal contracting devices. In communitarian developed countries, on the other hand, the stocks of institutional social capital have a stronger positive impact on LG dynamics.
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Health Behaviuor Interventions In Developing Countries
African Journals Online (AJOL)
health promotion interventions specifically focusing on developing countries would ... example from Kenya and Brazil of web-based education on adolescents' ... Master of Public Health, College of Medicine, University of Malawi. Reviewed by: ...
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Women's Health – A Continuing Challenge in Developing Countries
African Journals Online (AJOL)
Patrick Erah
Pharmacotherapy Group,. Faculty of Pharmacy, University of Benin,. Benin City, Nigeria. All rights reserved. Available online at http://www.tjpr.org. Editorial. Women's Health – A Continuing Challenge in. Developing Countries. For justifiable reasons, the health of women in developing countries is presently an important.
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Promoting energy efficiency in developing countries: The role of NGOs
International Nuclear Information System (INIS)
Wojtaszek, E.I.
1993-06-01
Developing countries need energy growth to spur economic growth. Yet energy activities contribute significantly to local water pollution and global greenhouse gas emissions. Energy efficiency offers the means to achieve the twin goals of sustainable economic/social development and environmental protection. Energy efficiency increases industrial competitiveness and frees up capital so it can be applied to other uses, such as health and education. The key to improving energy efficiency in developing countries will be acquiring and applying Western technologies, practices, and policies and building national institutions for promoting energy efficiency. Relevant energy-efficient technologies include the use of better electric motors, adjustable speed controls, combined cycle power cogeneration, improved lighting, better refrigeration technologies, and improved electric power transmission and distribution systems. Western countries can best help developing countries by providing guidance and resources to support nongovernmental organizations (NGOS) staffed by local experts; these institutions can capture the energy efficiency potential and ensure environmental protection in developing countries
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Nuclear desalting potential for developing countries
International Nuclear Information System (INIS)
1969-01-01
Nuclear power, having proved its success in large units, now poses problems for application in developing countries. Possible solutions for electricity supply, desalting systems and agricultural development are suggested by Joseph R. Wilson, of the Agency's Division of Nuclear Power and Reactors. His article is adapted from a lecture to students in Switzerland. (author)
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Nash, Michael J; Frank, Daniel N; Friedman, Jacob E
2017-01-01
The developing infant gut microbiome affects metabolism, maturation of the gastrointestinal tract, immune system function, and brain development. Initial seeding of the neonatal microbiota occurs through maternal and environmental contact. Maternal diet, antibiotic use, and cesarean section alter the offspring microbiota composition, at least temporarily. Nutrients are thought to regulate initial perinatal microbial colonization, a paradigm known as the "Restaurant" hypothesis. This hypothesis proposes that early nutritional stresses alter both the initial colonizing bacteria and the development of signaling pathways controlled by microbial mediators. These stresses fine-tune the immune system and metabolic homeostasis in early life, potentially setting the stage for long-term metabolic and immune health. Dysbiosis, an imbalance or a maladaptation in the microbiota, can be caused by several factors including dietary alterations and antibiotics. Dysbiosis can alter biological processes in the gut and in tissues and organs throughout the body. Misregulated development and activity of both the innate and adaptive immune systems, driven by early dysbiosis, could have long-lasting pathologic consequences such as increased autoimmunity, increased adiposity, and non-alcoholic fatty liver disease (NAFLD). This review will focus on factors during pregnancy and the neonatal period that impact a neonate's gut microbiome, as well as the mechanisms and possible links from early infancy that can drive increased risk for diseases including obesity and NAFLD. The complex pathways that connect diet, the microbiota, immune system development, and metabolism, particularly in early life, present exciting new frontiers for biomedical research.
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Selecting Tools for Renewable Energy Analysis in Developing Countries: An Expanded Review
Energy Technology Data Exchange (ETDEWEB)
Irsyad, M. Indra al [School of Earth and Environmental Science, University of Queensland, Brisbane, QLD (Australia); Ministry of Energy and Mineral Resources, Jakarta (Indonesia); Halog, Anthony Basco, E-mail: a.halog@uq.edu.au [School of Earth and Environmental Science, University of Queensland, Brisbane, QLD (Australia); Nepal, Rabindra [Massey Business School, Massey University, Palmerston North (New Zealand); Koesrindartoto, Deddy P. [School of Business and Management, Institut Teknologi Bandung, Bandung (Indonesia)
2017-12-20
Renewable energy planners in developing countries should be cautious in using analytical tools formulated in developed countries. Traditional energy consumption, economic and demography transitions, high-income inequality, and informal economy are some characteristics of developing countries that may contradict the assumptions of mainstream, widely used analytical tools. In this study, we synthesize the debate in previous review studies on energy models for developing countries and then extend the scope of the previous studies by highlighting emerging methods of system thinking, life cycle thinking, and decision support analysis. We then discuss how these tools have been used for renewable energy analysis in developing countries and found out that not all studies are aware of the emerging critical issues in developing countries. We offer here a guidance to select the most appropriate analytical tool, mainly when dealing with energy modeling and analysis for developing countries. We also suggest potential future improvements to the analytical tool for renewable energy modeling and analysis in the developing countries.
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Selecting Tools for Renewable Energy Analysis in Developing Countries: An Expanded Review
International Nuclear Information System (INIS)
Irsyad, M. Indra al; Halog, Anthony Basco; Nepal, Rabindra; Koesrindartoto, Deddy P.
2017-01-01
Renewable energy planners in developing countries should be cautious in using analytical tools formulated in developed countries. Traditional energy consumption, economic and demography transitions, high-income inequality, and informal economy are some characteristics of developing countries that may contradict the assumptions of mainstream, widely used analytical tools. In this study, we synthesize the debate in previous review studies on energy models for developing countries and then extend the scope of the previous studies by highlighting emerging methods of system thinking, life cycle thinking, and decision support analysis. We then discuss how these tools have been used for renewable energy analysis in developing countries and found out that not all studies are aware of the emerging critical issues in developing countries. We offer here a guidance to select the most appropriate analytical tool, mainly when dealing with energy modeling and analysis for developing countries. We also suggest potential future improvements to the analytical tool for renewable energy modeling and analysis in the developing countries.
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Corrupt practices negatively influenced food security and live expectancy in developing countries
Uchendu, Florence Ngozi; Abolarin, Thaddeus Olatunbosun
2015-01-01
Malnutrition is a global public health problem more prevalent in developing countries than in developed countries. Indicators of malnutrition include household food security and life expectancy. Corruption might be one of socio-political problems fuelling malnutrition in developing countries. The aim of this paper is to compare influence of corruption on food security, live expectancy (LE) and population in developed and developing countries. Thirty two least corrupt countries (LCC) and most corrupt countries (MCC) representing developed and developing countries were systematically selected using Corruption Perceptions Index (CPI). Countries’ data on population, food security index (FSI) and LE scores were obtained from Global food security index (GFSI) and Population reference bureau. T-test, Multivariate (Wilks’ Lambda), Pearson product moment analysis were performed to determine relationship between CPI, FSI, LE, and population in LCC and MCC at pcorrupt practices and promoting good governance should be embraced to eradicate malnutrition in developing countries. PMID:26090058
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Present and future of bioleaching in developing countries
Acevedo, Fernando
2002-01-01
Nowadays bioleaching occupies an increasingly important place among the available mining technologies. Today bioleaching is no longer a promising technology but an actual economical alternative for treating specific mineral ores. An important number of the current large-scale bioleaching operations are located in developing countries. This situation is determined by the fact that several developing countries have significant mineral reserves and by the characteristics of bioleaching that make...
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Kola-Lawal, Constance; Wood, Mike; Alo, Babajide; Clark, Andrew
2014-01-01
Country specificities and national cultures influence Environmental Management Systems (EMS) implementation and pro-environmental behaviour in organisations. Previous studies have focused on organisations in developed or emerging economies, creating a need to establish the extent to which findings are applicable to developing counterparts. This paper presents EMS implementation from a developing country perspective, reporting on EMS implementation factors (drivers, benefits, barriers) affecti...
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The Doha Development Agenda: Mixed Prospects for Developing Countries
Alan Matthews; Keith Walsh
2006-01-01
This paper uses the GTAP computable general equilibrium model to assess the impact of a Doha Development Agenda agreement on agricultural trade liberalisation. In particular, we examine the consequences for developing countries. The simulation incorporates further liberalisation in the areas of market access, export competition and domestic support. Most developing regions can expect strong positive results from this liberalisation, however some suffer a decrease in welfare. The magnitude of ...
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Can investments in health systems strategies lead to changes in immunization coverage?
Brenzel, Logan
2014-04-01
National immunization programs in developing countries have made major strides to immunize the world's children, increasing full coverage to 83% of children. However, the World Health Organization estimates that 22 million children less than five years of age are left unvaccinated, and coverage levels have been plateauing for nearly a decade. This paper describes the evidence on factors contributing to low vaccination uptake, and describes the connection between these factors and the documented strategies and interventions that can lead to changes in immunization outcomes. The author suggests that investments in these areas may contribute more effectively to immunization coverage and also have positive spill-over benefits for health systems. The paper concludes that while some good quality evidence exists of what works and may contribute to immunization outcomes, the quality of evidence needs to improve and major gaps need to be addressed.
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Impact of EU agricultural policy on developing countries
DEFF Research Database (Denmark)
Boysen, Ole; Jensen, Hans Grinsted; Matthews, Alan
2016-01-01
Despite substantial reforms, the EU’s Common Agricultural Policy (CAP) is still criticised for its detrimental effects on developing countries. This paper provides updated evidence on the impact of the CAP on one developing country, Uganda. It goes beyond estimating macro-level economic effects...... by analysing the impacts on poverty. The policy simulation results show that eliminating EU agricultural support would have marginal but nonetheless positive impacts on the Ugandan economy and its poverty indicators. From the perspective of the EU’s commitment to policy coherence for development, this supports...... the view that further reducing EU Agricultural support would be positive for development....
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Immune Evasion, Immunopathology and the Regulation of the Immune System
Directory of Open Access Journals (Sweden)
Bruno Faivre
2013-02-01
Full Text Available Costs and benefits of the immune response have attracted considerable attention in the last years among evolutionary biologists. Given the cost of parasitism, natural selection should favor individuals with the most effective immune defenses. Nevertheless, there exists huge variation in the expression of immune effectors among individuals. To explain this apparent paradox, it has been suggested that an over-reactive immune system might be too costly, both in terms of metabolic resources and risks of immune-mediated diseases, setting a limit to the investment into immune defenses. Here, we argue that this view neglects one important aspect of the interaction: the role played by evolving pathogens. We suggest that taking into account the co-evolutionary interactions between the host immune system and the parasitic strategies to overcome the immune response might provide a better picture of the selective pressures that shape the evolution of immune functioning. Integrating parasitic strategies of host exploitation can also contribute to understand the seemingly contradictory results that infection can enhance, but also protect from, autoimmune diseases. In the last decades, the incidence of autoimmune disorders has dramatically increased in wealthy countries of the northern hemisphere with a concomitant decrease of most parasitic infections. Experimental work on model organisms has shown that this pattern may be due to the protective role of certain parasites (i.e., helminths that rely on the immunosuppression of hosts for their persistence. Interestingly, although parasite-induced immunosuppression can protect against autoimmunity, it can obviously favor the spread of other infections. Therefore, we need to think about the evolution of the immune system using a multidimensional trade-off involving immunoprotection, immunopathology and the parasitic strategies to escape the immune response.
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Ebot, Jane O
2015-09-18
Although immunizations are efficient and cost effective methods of reducing child mortality, worldwide, approximately 2 million children die yearly of vaccine-preventable diseases. Researchers and health organizations have detailed information on the positive relationship between women's autonomy and children's health outcomes in developing countries. This study investigates the links between women's household autonomy and children's immunization status using data from a nationally representative sample of children aged 12-30 months (N = 2941) from the 2011 Ethiopia Demographic and Health Survey. The results showed that women's socioeconomic status and household autonomy were significantly associated with children's immunization status. Overall, the implications of this study align with those of the Millennium Development Goal #3: improvements in women's household autonomy are linked to more positive child health outcomes.
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Magnetic fusion research in developing countries
International Nuclear Information System (INIS)
Hassan, M.H.A.
1990-01-01
This article is a presentation prepared by the Third World Academy of Sciences on magnetic fusion research activity in the developing countries and its connection with the IAEA's own fusion programme. 6 figs, 1 tab
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Greenhouse gas emission reduction policies in developing countries
International Nuclear Information System (INIS)
Halsnaes, K.
2001-01-01
The chapter begins with an introduction of the main arguments for why global cost-effectiveness in GHG emission reduction policies will suggest that an international collaboration about the policies is established such as initiated by the Kyoto Protocol of the United Nations Framework Convention on Climate Change. A general conceptual overview is given on the cost concepts that are relevant to apply to the evaluation of GHG emission reduction policies, and the methodological framework of GHG emission reduction cost studies for developing countries are introduced. The studies have in particular focussed on GHG emission reduction options in the energy sector, and a number of costing results are reported for this sector. Finally, the chapter considers potential local side-impacts on development, the local environment, and social policy objectives of GHG emission reduction projects seen from the perspective of developing countries. It is concluded that there is a potential for combining global cost-effectiveness principles for GHG emission reduction policies, and local policy objectives of developing countries. (LN)
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Universal Health Coverage: A burning need for developing countries
Zaman, Sojib Bin; Hossain, Naznin
2017-01-01
The term of universal health coverage (UHC) are getting popularity among the countries who have not yet attained it. Majority of the developing countries are planning to implement the UHC to protect the vulnerable citizen who cannot afford to buy the health services. Poor people living in developing countries, where there is no UHC, are bereft of getting equal health care. They have to bear a significant amount of health cost in buying different services which often causes catastrophic expend...
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Improving Immunization Coverage in a Rural School District in Pierce County, Washington
Peterson, Robin M.; Cook, Carolyn; Yerxa, Mary E.; Marshall, James H.; Pulos, Elizabeth; Rollosson, Matthew P.
2012-01-01
Washington State has some of the highest percentages of school immunization exemptions in the country. We compared school immunization records in a rural school district in Pierce County, Washington, to immunization records in the state immunization information system (IIS) and parent-held records. Correcting school immunization records resulted…
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Suppressing epidemics with a limited amount of immunization units.
Schneider, Christian M; Mihaljev, Tamara; Havlin, Shlomo; Herrmann, Hans J
2011-12-01
The way diseases spread through schools, epidemics through countries, and viruses through the internet is crucial in determining their risk. Although each of these threats has its own characteristics, its underlying network determines the spreading. To restrain the spreading, a widely used approach is the fragmentation of these networks through immunization, so that epidemics cannot spread. Here we develop an immunization approach based on optimizing the susceptible size, which outperforms the best known strategy based on immunizing the highest-betweenness links or nodes. We find that the network's vulnerability can be significantly reduced, demonstrating this on three different real networks: the global flight network, a school friendship network, and the internet. In all cases, we find that not only is the average infection probability significantly suppressed, but also for the most relevant case of a small and limited number of immunization units the infection probability can be reduced by up to 55%.
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Globalization and Industrialization in 64 Developing Countries, 1980-2003
Kaya, Yunus
2010-01-01
This study investigates the effect of the latest wave of economic globalization on manufacturing employment in developing countries. It revisits the classic debate on the effect of internal and external influences on industrialization, and extends this debate to contemporary developing countries. In the process, it assesses the evidence for…
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Corporate Governance Practices in Developing Countries: The Case for Kenya
Benjamin Mwanzia Mulili; Dr. Peter Wong
2011-01-01
This paper examines the concept of corporate governance from a historical perspective. The paper explores how the agency theory and stewardship theory affect corporate governance practices. The focus of the paper is on public universities in Kenya. An extensive review of literature indicates that the ideals of good corporate governance have been adopted by developing countries since the 1980s. Developing countries differ from developed countries in a wide variety of ways. Therefore, there is ...
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International Nuclear Information System (INIS)
Cavard, D.; Cornut, P.; Menanteau, P.
2001-01-01
Refusal of developing countries to commit themselves to the implementation of climate change agreements on the grounds that their cumulated emissions would have little impact on climate change, combined with their need for increase in energy consumption to meet their economic development needs, has been one of the stumbling blocks to agreement since the beginning of climate change negotiations. For these and a variety of other reasons the Clean Development Mechanism (CDM) is important for industrialized and developing countries alike since it has the promise of benefiting both parties: industrialized countries benefit from low cost emission reductions, while CDM will stimulate economic development in developing countries. This paper examines the rules of the Clean Development Mechanism in order to validate project additions (as yet unresolved), and its possible consequences on the effectiveness and the scope of the mechanism. Also examined are the three basic approaches to CDM implementation (bilateral, unilateral. multilateral), the different reactions of major developing country groups to the structure of the mechanism, and the possibilities of widening the scope of action of the CDM to include sectoral and program-based aspects. In this context, 'voluntary, non-binding' emission commitments, establishment of a reference scenario for developing countries, related concerns about sustainable development, national sovereignty issues, equity in funding and vulnerability, are some of the potential issues highlighted. 33 footnotes
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Industrial Clusters and Social Upgrading in Developing Countries
DEFF Research Database (Denmark)
Pyke, Frank; Lund-Thomsen, Peter
In this article, we explore the relationship between industrial clusters and social upgrading in developing countries. Our article focuses on the hitherto little-considered influence of the economic and regulatory environment on the social upgrading of a cluster and on its governance system....... In doing so, we develop an analytical framework that seeks to explain how the enabling environment and different actors in cluster governance can either facilitate and/or hinder the process of social upgrading in cluster settings in developing countries. Finally, the conclusion outlines our main findings...
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Agricultural biotechnology and smallholder farmers in developing countries.
Anthony, Vivienne M; Ferroni, Marco
2012-04-01
Agricultural biotechnology holds much potential to contribute towards crop productivity gains and crop improvement for smallholder farmers in developing countries. Over 14 million smallholder farmers are already benefiting from biotech crops such as cotton and maize in China, India and other Asian, African and Central/South American countries. Molecular breeding can accelerate crop improvement timescales and enable greater use of diversity of gene sources. Little impact has been realized to date with fruits and vegetables because of development timescales for molecular breeding and development and regulatory costs and political considerations facing biotech crops in many countries. Constraints to the development and adoption of technology-based solutions to reduce yield gaps need to be overcome. Full integration with broader commercial considerations such as farmer access to seed distribution systems that facilitate dissemination of improved varieties and functioning markets for produce are critical for the benefits of agricultural biotechnology to be fully realized by smallholders. Public-private partnerships offer opportunities to catalyze new approaches and investment while accelerating integrated research and development and commercial supply chain-based solutions. Copyright © 2011. Published by Elsevier Ltd.
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Subnational Taxes in Developing Countries: The Way Forward.
Richard M. Bird; Roy Bahl
2008-01-01
This paper reviews the literature and evidence on the most appropriate structure of regional and local taxes in developing countries. A good subnational tax system is critical to an effective and sustainable system of intergovernmental fiscal relations – a need that has become increasingly important around the world as more and more public services are being delivered through subnational governments. In most developing countries potentially sound and productive taxes exist that are suitable f...
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Bank concentration, country income and financial development in ...
African Journals Online (AJOL)
kirstam
between bank concentration and financial development in the SADC region. ... 5The study findings suggest that bank assets in SADC are concentrated in ... a country's cities/administrative regions, or across countries within a regional ... sector emphasises the importance of local embeddedness, networks, ...... The Case of.
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Capacity building in renewable energy technologies in developing countries
Energy Technology Data Exchange (ETDEWEB)
Fridleifsson, Ingvar
2010-09-15
The renewable energy sources are expected to provide 20-40% of the world primary energy in 2050, depending on scenarios. A key element in the mitigation of climate change is capacity building in renewable energy technologies in the developing countries, where the main energy use growth is expected. An innovative training programme for geothermal energy professionals developed in Iceland is an example of how this can be done effectively. In 1979-2009, 424 scientists/engineers from 44 developing countries have completed the 6 month courses. In many countries in Africa, Asia, C-America, and E-Europe, UNU-GTP Fellows are among the leading geothermal specialists.
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Canada and the Kyoto Protocol: Fact Sheet No. 5 - Developing countries
International Nuclear Information System (INIS)
2000-11-01
This fact sheet acknowledges that global change affects developed and developing countries alike, and the fact that most developing countries do not have the human, financial and technical capacity to effectively address climate change issues without help from the industrialized nations. The fact sheet also puts Canada on record as being in agreement with the spirit of the Kyoto Protocol to encourage the participation of developing countries in global efforts to combat climate change and promote sustainable development and reaffirms Canada's willingness to provide financial and technical assistance to developing countries to enable them to play a meaningful part in this global effort. In this context, the fact sheet briefly describes the new Canada Climate Change Development Fund which has been set up to reduce the growth of GHG emissions and support carbon sink activities in developing countries, to strengthen the capacity of developing conuntries to reduce their vulnerability to adverse effects of climate change, and to participate in global efforts to combat them
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Kabir, Fayzul; Chowdhury, Shakhawat
2017-11-01
Arsenic pollution of drinking water is a concern, particularly in the developing countries. Removal of arsenic from drinking water is strongly recommended. Despite the availability of efficient technologies for arsenic removal, the small and rural communities in the developing countries are not capable of employing most of these technologies due to their high cost and technical complexity. There is a need for the "low-cost" and "easy to use" technologies to protect the humans in the arsenic affected developing countries. In this study, arsenic removal technologies were summarized and the low-cost technologies were reviewed. The advantages and disadvantages of these technologies were identified and their scopes of applications and improvements were investigated. The costs were compared in context to the capacity of the low-income populations in the developing countries. Finally, future research directions were proposed to protect the low-income populations in the developing countries.
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Private health insurance: implications for developing countries.
Sekhri, Neelam; Savedoff, William
2005-02-01
Private health insurance is playing an increasing role in both high- and low-income countries, yet is poorly understood by researchers and policy-makers. This paper shows that the distinction between private and public health insurance is often exaggerated since well regulated private insurance markets share many features with public insurance systems. It notes that private health insurance preceded many modern social insurance systems in western Europe, allowing these countries to develop the mechanisms, institutions and capacities that subsequently made it possible to provide universal access to health care. We also review international experiences with private insurance, demonstrating that its role is not restricted to any particular region or level of national income. The seven countries that finance more than 20% of their health care via private health insurance are Brazil, Chile, Namibia, South Africa, the United States, Uruguay and Zimbabwe. In each case, private health insurance provides primary financial protection for workers and their families while public health-care funds are targeted to programmes covering poor and vulnerable populations. We make recommendations for policy in developing countries, arguing that private health insurance cannot be ignored. Instead, it can be harnessed to serve the public interest if governments implement effective regulations and focus public funds on programmes for those who are poor and vulnerable. It can also be used as a transitional form of health insurance to develop experience with insurance institutions while the public sector increases its own capacity to manage and finance health-care coverage.
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Challenges for nationwide vaccine delivery in African countries.
Songane, Mario
2017-10-19
Vaccines are very effective in providing individual and community (herd) immunity against a range of diseases. In addition to protection against a range of diseases, vaccines also have social and economic benefits. However, for vaccines to be effective, routine immunization programmes must be undertaken regularly to ensure individual and community protection. Nonetheless, in many countries in Africa, vaccination coverage is low because governments struggle to deliver vaccines to the most remote areas, thus contributing to constant outbreaks of various vaccine-preventable diseases. African governments fail to deliver vaccines to a significant percentage of the target population due to many issues in key areas such as policy setting, programme management and financing, supply chain, global vaccine market, research and development of vaccines. This review gives an overview of the causes of these issues and what is currently being done to address them. This review will discuss the role of philanthropic organisations such as the Bill and Melinda Gates Foundation and global partnerships such as the global alliance for vaccines and immunizations in the development, purchase and delivery of vaccines.
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International Nuclear Information System (INIS)
Siwar, C.; Hossain, E.
2005-01-01
Despite significantly contributing to country's overall economic development through providing employment for the people and supplying raw materials for agro- and resource based industrial development, agriculture is putting serious burden on the environment in the process of production and consumption of agricultural produce. It is the largest consumer and polluter of water resources and contributor of atmospheric pollution, land degradation and forest reduction. Agriculture-environmental relationship is complex and the relationship depends on the spatial and biophysical factors and country's level of economic development. This paper tried to document the linkages between agricultural practices and policies with environment. The channels, through which agriculture impacts the environment, is discussed. It is seen that multilateral trade liberalization in agriculture interacts with the domestic agricultural policy reforms to determine the environmental impacts of agriculture. It is seen that agricultural policy reforms and agricultural trade liberalization can have separate environmental effects in the developed and developing countries. A wide range of theoretical and empirical literatures are reviewed, in this paper, to understand the concepts, linkages and environmental problems. Finally, this paper ends up with the conclusion that integrating environmental considerations into domestic agricultural policies and implementing agro-environmental programmes may ensure the decline of environmental problems of agriculture in both the developed and developing countries. (author)
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The key issues facing the electricity systems of developing countries
International Nuclear Information System (INIS)
Oliveira, A. de
1991-01-01
This report covers a common project designed to investigate the major issues and possible future direction in the electricity systems of developing countries in AFRICA, ASIA and LATIN AMERICA. Individual centres each had responsibility for preparing a detailed report on the experiences and issues in their own country plus a regional report, in less detail, to cover neighbouring countries. In this disaggregated way, a picture of the whole of the developing world (with the exception of the Middle East, the problems of which are in some ways distinct from those of other developing countries) has been built up. 30 Refs.; 14 Figs.; 33 Tabs
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Wood biomass gasification: Technology assessment and prospects in developing countries
International Nuclear Information System (INIS)
Salvadego, C.
1992-05-01
This investigation of the technical-economic feasibility of the development and use of wood biomass gasification plants to help meet the energy requirements of developing countries covers the following aspects: resource availability and production; gasification technologies and biomass gasification plant typology; plant operating, maintenance and safety requirements; the use of the biomass derived gas in internal combustion engines and boilers; and the nature of energy requirements in developing countries. The paper concludes with a progress report on biomass gasification research programs being carried out in developing countries world-wide
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Energy indicators for tracking sustainability in developing countries
International Nuclear Information System (INIS)
Kemmler, Andreas; Spreng, Daniel
2007-01-01
Due to the fact that human activities and most sustainability issues are closely related to energy use, the energy system is a sound framework for providing lead indicators for sustainable development. Common energy-economic models enable the estimation of future states of the energy system. An energy system-based lead indicator set can be used to develop consistent and coherent future indicator estimates and to track sustainability, a clear advantage over existing sets. In developed countries, the sustainability discussion is focused on environmental topics, while in developing countries the issues of poverty and equity are equally important. Consequently, for measuring sustainable development in a developing country, the inclusion of a poverty indicator in a set of lead indicators is essential. By correlation and descriptive analysis, it is shown that reliable energy-based indicators of poverty can be created. Although no one-dimensional indicator is a comprehensive measure of poverty, the explanatory power of energy poverty indicators is comparable to that of other poverty indicators. Thus, the use of energy indicators is not restricted to environmental and economic issues but is also relevant for social issues
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Is astronomical research appropriate for developing countries?
Snowden, Michael S.
An unproductive 45-cm astronomical telescope, given by JICA (Japan) to Sri Lanka, raises general questions as to the reasons for unproductive pure science in developing countries. Before installation, site, maintenance, and scientific objectives were discussed. The facility was launched with a conference organised by the UN Office for Outer Space Affairs. Unfortunately, no research or significant education has resulted after four years. The annual operating cost is U.S. $5000 per year, including salary for a trainee, maintenance, and a modest promotional programme. Comparison with a similar installation in Auckland suggests lack of funding or technical competence do not explain the failure in Sri Lanka. The facility in New Zealand, on the roof of Auckland University's Physics Department, has a slightly smaller budget but has led to modest but useful research and teaching. Lack of financial backing and expertise are often blamed for weak science in developing countries, but examination shows most of these countries have adequately skilled people, and plenty of resources for religion and military. General lack of motivation for science appears to be the principal reason. This lack of interest and highly inefficient bureaucracies are common to scientifically unproductive countries. They mostly lack the cultural and philosophical base of the European Renaissance that motivate the pursuit of modern science, an activity that violates human preferences. There are excellent facilities (ESO, SAAO, Cerro Tololo, and GONG) in some of these same countries, when administered from the West.
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Directory of Open Access Journals (Sweden)
Raveesha R. Mugali
2017-04-01
Full Text Available Abstract Background Despite progress in recent years, Afghanistan is lagging behind in realizing the full potential of immunization. The country is still endemic for polio transmission and measles outbreaks continue to occur. In spite of significant reductions over the past decade, the mortality rate of children under 5 years of age continues to remain high at 91 per 1000 live births. Methods The study was a descriptive community-based cross sectional household survey. The survey aimed to estimate the levels of immunization coverage at national and province levels. Specific objectives are to: establish valid baseline information to monitor progress of the immunization program; identify reasons why children are not immunized; and make recommendations to enhance access and quality of immunization services in Afghanistan. The survey was carried out in all 34 provinces of the country, with a sample of 6125 mothers of children aged 12–23 months. Results Nationally, 51% of children participating in the survey received all doses of each antigen irrespective of the recommended date of immunization or recommended interval between doses. About 31% of children were found to be partially vaccinated. Reasons for partial vaccination included: place to vaccinate child too far (23%, not aware of the need of vaccination (17%, no faith in vaccination (16%, mother was too busy (15%, and fear of side effects (11%. Conclusion The innovative mechanism of contracting out delivery of primary health care services in Afghanistan, including immunization, to non-governmental organizations is showing some positive results in quickly increasing coverage of essential interventions, including routine immunization. Much ground still needs to be covered with proper planning and management of resources in order to improve the immunization coverage in Afghanistan and increase survival and health status of its children.
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Promoting biofuels: Implications for developing countries
International Nuclear Information System (INIS)
Peters, Joerg; Thielmann, Sascha
2008-01-01
Interest in biofuels is growing worldwide as concerns about the security of energy supply and climate change are moving into the focus of policy makers. With the exception of bioethanol from Brazil, however, production costs of biofuels are typically much higher than those of fossil fuels. As a result, promotion measures such as tax exemptions or blending quotas are indispensable for ascertaining substantial biofuel demand. With particular focus on developing countries, this paper discusses the economic justification of biofuel promotion instruments and investigates their implications. Based on data from India and Tanzania, we find that substantial biofuel usage induces significant financial costs. Furthermore, acreage availability is a binding natural limitation that could also lead to conflicts with food production. Yet, if carefully implemented under the appropriate conditions, biofuel programs might present opportunities for certain developing countries
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Financing Renewable Energy Projects in Developing Countries: A Critical Review
Donastorg, A.; Renukappa, S.; Suresh, S.
2017-08-01
Access to clean and stable energy, meeting sustainable development goals, the fossil fuel dependency and depletion are some of the reasons that have impacted developing countries to transform the business as usual economy to a more sustainable economy. However, access and availability of finance is a major challenge for many developing countries. Financing renewable energy projects require access to significant resources, by multiple parties, at varying points in the project life cycles. This research aims to investigate sources and new trends in financing RE projects in developing countries. For this purpose, a detail and in-depth literature review have been conducted to explore the sources and trends of current RE financial investment and projects, to understand the gaps and limitations. This paper concludes that there are various internal and external sources of finance available for RE projects in developing countries.
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The income elasticity of health care spending in developing and developed countries.
Farag, Marwa; NandaKumar, A K; Wallack, Stanley; Hodgkin, Dominic; Gaumer, Gary; Erbil, Can
2012-06-01
To date, international analyses on the strength of the relationship between country-level per capita income and per capita health expenditures have predominantly used developed countries' data. This study expands this work using a panel data set for 173 countries for the 1995-2006 period. We found that health care has an income elasticity that qualifies it as a necessity good, which is consistent with results of the most recent studies. Furthermore, we found that health care spending is least responsive to changes in income in low-income countries and most responsive to in middle-income countries with high-income countries falling in the middle. Finally, we found that 'Voice and Accountability' as an indicator of good governance seems to play a role in mobilizing more funds for health.
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Horticultural Exports of Developing Countries: Issues under WTO Regime
Directory of Open Access Journals (Sweden)
Deepak Shah
2008-03-01
Full Text Available This paper seeks to evaluate the present and future prospects of developing and developed countries in agricultural exports in general and in horticultural exports in particular. The study also evaluates the behaviour of international export prices for agricultural commodities, both for developing and developed nations. In general, this study provides an insight into the direction in which various developed and developing countries are heading for insofar as their agricultural and horticultural exports are concerned in the changed market conditions. The study has made a few major observations. First, the study shows decline in market share of developing countries’ in world agricultural exports in the face of marginal increase in their market share in world fruits and vegetable (F&V exports during the period between 1981 and 1997. Second, although the study shows lower market share of developing countries’ in world F&V exports during the period between 1981 and 1997, the growth in F&V exports as proportion of total agricultural exports is noticed to be much faster for developing countries’ as against the developed countries’ during the same period. Third, though agricultural exports of Least Developed Countries (LDC have grown only marginally between 1981 and 1997, the growth in their F&V exports is seen to have been tremendous, especially after the late eighties period. Similarly, Socialist Countries of Asia (SCA and developing countries of Oceania have also shown sharp increases in their F&V exports after the late eighties period. Fourth, while except America, other Africa and Oceania, all the developing countries have shown decline in their market share in total F&V exports of Developing Market Economies (DME, Asia shows rise in its market share not only in agriculture but also in F&V exports of DME. Another major observation of this study is in terms of instabilities in export prices. The instabilities in export prices of agricultural
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Policy options for developing Asian countries in the Post-Kyoto world
International Nuclear Information System (INIS)
Siddiqi, Toufiq A.
2003-01-01
The developing countries of Asia are amongst the largest contributors to the anthropogenic emissions of greenhouse gases as well as being amongst those most likely to be impacted by global climate change. There are at present no legal requirements for the Asian developing countries to reduce their emissions, however, the medium and long-term impact of global climate change is likely to be proportionately larger for the developing countries than for the industrialized countries, since the latter have the resources to reduce the adverse impacts. Therefore, it is of great interest of the developing countries, as well as the rest of the world, to have longer-term goals for stabilizing their greenhouse gas emissions, and taking actions during the medium term to achieve these goals. Asia is home to about 50% of the world's population, and there is great variation in the levels of industrialization and contribution to greenhouse gas emissions. A differentiated strategy for addressing concerns related to global climate change may be appropriate for the Asian developing countries at this time. Some elements of this strategy are discussed in this paper. Development in energy technology present several attractive options for the developing countries. However, their introduction and successful use depends at least as much on the existence of the necessary infrastructure as on the attractiveness of the technologies themselves. It is suggested that international and bilateral development agencies, as well as the countries themselves, consider the accelerated development of such infrastructure as a major way to contribute to the efforts to address global climate change. (BA)
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The Roots of Gender Inequality in Developing Countries
Seema Jayachandran
2014-01-01
Is the high degree of gender inequality in developing countries--in education, personal autonomy, and more--explained by underdevelopment itself? Or do the societies that are poor today hold certain cultural views that lead to gender inequality? This article discusses several mechanisms through which, as countries grow, gender gaps narrow. I argue that while much of the GDP/gender-inequality relationship can be explained by the process of development, society-specific factors are also at play...
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Strategies and challenges for safe injection practice in developing countries.
Gyawali, Sudesh; Rathore, Devendra Singh; Shankar, P Ravi; Kumar, Kc Vikash
2013-01-01
Injection is one of the important health care procedures used globally to administer drugs. Its unsafe use can transmit various blood borne pathogens. This article aims to review the history and status of injection practices, its importance, interventions and the challenges for safe injection practice in developing countries. The history of injections started with the discovery of syringe in the early nineteenth century. Safe injection practice in developed countries was initiated in the early twentieth century but has not received adequate attention in developing countries. The establishment of "Safe Injection Global Network (SIGN)" was an milestone towards safe injection practice globally. In developing countries, people perceive injection as a powerful healing tool and do not hesitate to pay more for injections. Unsafe disposal and reuse of contaminated syringe is common. Ensuring safe injection practice is one of the greatest challenges for healthcare system in developing countries. To address the problem, interventions with active involvement of a number of stakeholders is essential. A combination of educational, managerial and regulatory strategies is found to be effective and economically viable. Rational and safe use of injections can save many lives but unsafe practice threatens life. Safe injection practice is crucial in developing countries. Evidence based interventions, with honest commitment and participation from the service provider, recipient and community with aid of policy makers are required to ensure safe injection practice.
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Castiglia, Paolo
2014-10-01
The global burden of pneumococcal diseases is high, with young children and adults≥50 years of age at highest risk of infection. Two types of vaccine are available for the prevention of pneumococcal diseases caused by specific Streptococcus pneumoniae serotypes: the pneumococcal polysaccharide vaccine (PPV23) and the pneumococcal conjugate vaccine (PCV7, PCV10, and PCV13). Despite pneumococcal immunization programs in adults and children, the burden in adults has remained high. Most European countries have national or local/regional vaccination recommendations. The objective of this review was to provide an overview of the government recommendations for pneumococcal vaccination outside routine childhood vaccination programs for 16 Western European countries as of August 2014. We found that recommendations for pneumococcal immunization across Europe are complex and vary greatly among countries in terms of age groups and risk groups recommended for vaccination, as well as which vaccine should be administered. Clarifying or simplifying these recommendations and improving their dissemination could help to increase pneumococcal vaccine uptake and decrease the high burden of pneumococcal diseases in adults, both through a direct effect of the vaccine and via a herd effect in unvaccinated individuals.
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Taxes and Economic Growth in Developing Countries : A Dynamic Panel Approach
NANTOB, N'Yilimon
2014-01-01
This paper looks at the effects of taxes increase on economic growth of 47 developing countries. In developing countries, there is no magic tax strategy to encourage economic growth. Some countries with high tax burdens have high growth rates and some countries with low tax burdens have low growth rates. Despite much theoretical and empirical inquiry as well as political and policy controversy, no simple answer exists concerning the relationship of taxes on economic growth in developing count...
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Immune Responses Involved in Mycobacterium Tuberculosis Infection
Directory of Open Access Journals (Sweden)
Roghayeh Teimourpour
2016-09-01
Full Text Available Background and Objectives: Mycobacterium tuberculosis is the causative agent of tuberculosis (TB. Approximately one-third of the world's population is infected with M. tuberculosis. Despite the availability of drug and vaccine, it remains one of the leading causes of death in humans especially in developing countries. Epidemiological studies have indicated that only 10-30% of people exposed to tubercle bacillus are infected with M. tuberculosis, and at least 90% of the infected people finally do not acquire TB. The studies have indicated that the host efficient immune system has essential roles in the control of TB infection such that the highest rate of mortality and morbidity is seen in immunocompromised patients such as people infected with HIV. M. tuberculosis is an obligatory intracellular bacterium. It enters the body mainly through the respiratory tract and alveolar macrophages combat this pathogen most commonly. In addition to alveolar macrophages, various T-cell subpopulations need to be activated to overcome this bacterium's resistance to the host defense systems. CD4+ T cells, through production of several cytokines such as IFN-γ and TNF-α, and CD8+ T cells, through cytotoxic activities and induction of apoptosis in infected cells, play critical roles in inducing appropriate immune responses against M. tuberculosis. Although cell-mediated immunity is the cornerstone of host responses against TB and the recent studies have provided evidence for the importance of humoral and innate immune system in the control of TB, a profound understanding of the immune responses would provide a basis for development of new generations of vaccines and drugs. The present study addresses immune responses involved in M. tuberculosis infection.
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The Double Burden of Undernutrition and Overnutrition in Developing Countries: an Update.
Abdullah, Asnawi
2015-09-01
Many developing countries have achieved a remarkable improvement in nutrition status in the past decades. However, the prevalence of undernutrition remains a serious problem. At the same time, the prevalence of obesity is increasing substantially, and in some countries, it has approached that of developed countries. This article provides an update on this double burden of malnutrition (DBMN) in developing nations. One hundred countries (lower, middle-lower, and upper-middle income countries) were selected and analysed, and to support the analysis, a systematic review of current published studies was performed. The results show that DBMN already exists in almost all developing countries and that the DBMN ratio (i.e., overweight/underweight) has increased as income per capita has increased. DBMN may manifest within the community, household, or individual. In addition to common factors, poor nutrition in early childhood is suggested as another important driving factor behind the rising obesity rate in most developing countries. A life-course approach has been proposed to prevent undernutrition and overnutrition and should be integrated into the development of health systems to control double burden in developing countries.
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Handling e-waste in developed and developing countries: Initiatives, practices, and consequences
Energy Technology Data Exchange (ETDEWEB)
Sthiannopkao, Suthipong, E-mail: suthisuthi@gmail.com [Department of Environmental Engineering, College of Engineering, Dong-A University, 37 Nakdong-Daero 550 beon-gil Saha-gu, Busan (Korea, Republic of); Wong, Ming Hung [Croucher Institute for Environmental Sciences, Hong Kong Baptist University, Hong Kong (China)
2013-10-01
Discarded electronic goods contain a range of toxic materials requiring special handling. Developed countries have conventions, directives, and laws to regulate their disposal, most based on extended producer responsibility. Manufacturers take back items collected by retailers and local governments for safe destruction or recovery of materials. Compliance, however, is difficult to assure, and frequently runs against economic incentives. The expense of proper disposal leads to the shipment of large amounts of e-waste to China, India, Pakistan, Nigeria, and other developing countries. Shipment is often through middlemen, and under tariff classifications that make quantities difficult to assess. There, despite the intents of national regulations and hazardous waste laws, most e-waste is treated as general refuse, or crudely processed, often by burning or acid baths, with recovery of only a few materials of value. As dioxins, furans, and heavy metals are released, harm to the environment, workers, and area residents is inevitable. The faster growth of e-waste generated in the developing than in the developed world presages continued expansion of a pervasive and inexpensive informal processing sector, efficient in its own way, but inherently hazard-ridden. - Highlights: ► Much e-waste, expensive to process safely, illegally goes to developing countries. ► E-waste processing in developing countries pollutes with heavy metals and dioxins. ► Well-conceived developing world waste regulations lack enforceability. ► Crude e-waste processing cannot recover several rare materials. ► The amount of e-waste unsafely processed will continue to grow.
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Handling e-waste in developed and developing countries: Initiatives, practices, and consequences
International Nuclear Information System (INIS)
Sthiannopkao, Suthipong; Wong, Ming Hung
2013-01-01
Discarded electronic goods contain a range of toxic materials requiring special handling. Developed countries have conventions, directives, and laws to regulate their disposal, most based on extended producer responsibility. Manufacturers take back items collected by retailers and local governments for safe destruction or recovery of materials. Compliance, however, is difficult to assure, and frequently runs against economic incentives. The expense of proper disposal leads to the shipment of large amounts of e-waste to China, India, Pakistan, Nigeria, and other developing countries. Shipment is often through middlemen, and under tariff classifications that make quantities difficult to assess. There, despite the intents of national regulations and hazardous waste laws, most e-waste is treated as general refuse, or crudely processed, often by burning or acid baths, with recovery of only a few materials of value. As dioxins, furans, and heavy metals are released, harm to the environment, workers, and area residents is inevitable. The faster growth of e-waste generated in the developing than in the developed world presages continued expansion of a pervasive and inexpensive informal processing sector, efficient in its own way, but inherently hazard-ridden. - Highlights: ► Much e-waste, expensive to process safely, illegally goes to developing countries. ► E-waste processing in developing countries pollutes with heavy metals and dioxins. ► Well-conceived developing world waste regulations lack enforceability. ► Crude e-waste processing cannot recover several rare materials. ► The amount of e-waste unsafely processed will continue to grow
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Integrating developing country manufacturing industries into global supply chain
Directory of Open Access Journals (Sweden)
Fasika Bete Georgise
2014-01-01
Full Text Available Purpose: Due to globalization of manufacturing activities, the arena of competition and competitiveness advantage is moving from firms towards supply chains and networks. With the recent advancement of information and communication technologies this participation are becoming as common business practice in developed countries firms. Companies were more integrated into the world market for the global nature of the sourcing, manufacturing and distribution. These changes create both challenges and opportunities for the manufacturing industries in developing countries. The objective of this paper is to examine the level of inter-organizational and intra-organizational supply chain integration practices in developing country, Ethiopia.Design/methodology/approach: An industrial questionnaires survey was used to collect the current practices of the manufacturing industries in Ethiopia as an example of the developing countries. Descriptive statistics is primarily used for the analysis.Findings: Results show a low level of supply chain relationship both in intra and inter organizational supply chain integration level among members. Accordingly, such issues require much attention to facilitate a greater integration within the supply chains in the Ethiopian manufacturing industries.Research limitations/implications: The paper focuses on examining the practices of Ethiopian manufacturing industries empirical data. The interpretation of results should be taken with prudence.Originality/Value: The manufacturing industry in developing countries (MIDC has been a part of the global supply chains for long time as a supplier of raw material and manufacturer of primary products. Currently, the MIDC is trying to access the different markets segment of the world even with new products starting from their local market to the complex and dynamic international market. Nevertheless, their supply chains are inefficient and hence, their competitiveness level far from the
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Private power in developing countries: Exporting the American experience
International Nuclear Information System (INIS)
Rogers, W.L.; Bourgeacq, J.P.
1990-01-01
This paper discusses using American marketing and financing expertise and technology to meet the need for increased power production and efficiency in developing countries. The topics of the paper include the opportunity for independent power production, dangers in international development, foreign country market evaluation, the criteria for selection, and taking advantage of the opportunities
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International Nuclear Information System (INIS)
Rose, Adam; Wei Dan
2008-01-01
This paper examines the aggregate net costs and individual country cost savings of greenhouse gas emissions trading among Pacific Rim countries. We propose emission permit allocation rules designed to entice developing countries to participate. Absence of developing country involvement has served as an excuse for the lack by participation by the United States in the first compliance period of the Kyoto Protocol and may serve as a disincentive to even more countries in subsequent periods. Our analysis specifies permit allocation rules that could result in no net costs, and even cost-savings, to developing countries for their involvement in the emissions trading market, while at the same time providing extensive benefits to industrialized countries through access to lower-cost mitigation alternatives
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Transformation of intimacy and its impact in developing countries.
Muniruzzaman, M D
2017-12-01
Nowadays intimacy or intimate relationship is very familiar and widely used term all over the world. The term 'Intimacy' generally denotes a close interpersonal relationship or feeling of being in a close personal association and belonging together from both physical and mental point of view. It also denotes very close and effective connection with one another which may exist for whole life or may not. This article has been prepared on the basis of secondary sources and it tries to explore how this intimacy or intimate relationship has been gradually transforming from pre-modern society to modern society and from modern society to post-modern society for over the eras. This article also tries to explore the impact of transformed intimacy or intimate relationship, especially in the developing countries, like Bangladesh. Intimate relationship plays very significant role in the overall life style of any human being. This relationship includes feelings of liking, romance, sexuality or sexual relationship, emotional or personal support between mates. But the role of sexuality or sexual relationship is gradually increasing in intimacy, not only in the western countries but also in the developing countries. Nowadays people are involved with many kinds of premarital and extramarital relationships and they try to avoid the risk of reproduction. This tendency creates many problems in the developing countries, as most of the people of such developing countries are poor and illiterate. They are not aware about the dangerous impact of unsafe physical or sexual relationship. So the people of developing countries like Bangladesh are very vulnerable in the aspect of erosion of values and spreading different types of sexually transmitted diseases.
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Direct‐to‐consumer advertising of pharmaceuticals: developed countries experiences and Turkey
Semin, Semih; Aras, Şahbal; Guldal, Dilek
2006-01-01
Abstract While several major problems concerning drugs occur in the world, the attempts to direct‐to‐consumer advertising (DTCA) has gained a considerable impetus lately in both developed and developing countries. DTCA has increasingly become an appealing advertising alternative for the pharmaceutical industry as drug companies have come to wrestle with such problems as the expansion of the drug market; the decline of the medical representatives’ work efficiency; drug reimbursement restrictions; and the escalating role of the Internet in the consumer market. Some of the main disadvantages of the DTCA are: increasing drug expenditures, unnecessary drug consumption and adverse effect risks. Even though the influence of pharmaceuticals on health services and the economy hold the same importance in the developed and developing countries, its negative consequences have increased by encompassing developing countries in its grip. Therefore, in this review, using Turkey as an example, the situation of direct‐to‐consumer advertisements in developing countries is analysed in relation with developed countries. PMID:17324191
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Direct-to-consumer advertising of pharmaceuticals: developed countries experiences and Turkey.
Semin, Semih; Aras, Sahbal; Guldal, Dilek
2007-03-01
While several major problems concerning drugs occur in the world, the attempts to direct-to-consumer advertising (DTCA) has gained a considerable impetus lately in both developed and developing countries. DTCA has increasingly become an appealing advertising alternative for the pharmaceutical industry as drug companies have come to wrestle with such problems as the expansion of the drug market; the decline of the medical representatives' work efficiency; drug reimbursement restrictions; and the escalating role of the Internet in the consumer market. Some of the main disadvantages of the DTCA are: increasing drug expenditures, unnecessary drug consumption and adverse effect risks. Even though the influence of pharmaceuticals on health services and the economy hold the same importance in the developed and developing countries, its negative consequences have increased by encompassing developing countries in its grip. Therefore, in this review, using Turkey as an example, the situation of direct-to-consumer advertisements in developing countries is analysed in relation with developed countries.
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Economic valuation of aquatic ecosystem services in developing countries
DEFF Research Database (Denmark)
Korsgaard, Louise; Schou, Jesper S.
2010-01-01
-the silent water user. A promising way of placing aquatic ecosystems on the water agenda is by economic valuation of services sustained by ecosystems. In developing countries, the livelihoods of rural people often depend directly on the provision of aquatic ecosystem services. In such situations, economic......An important challenge of integrated water resources management (IWRM) is to balance water allocation between different users. While economically and/or politically powerful users have well developed methods for quantifying and justifying their water needs, this is not the case for ecosystems...... valuation of ecosystem services becomes particularly challenging. This paper reviews recent literature on economic valuation of aquatic ecosystem services in developing countries. "Market price" is the most widespread method used for valuating marketed ecosystem services in developing countries. "Cost based...
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Infertility and the provision of infertility medical services in developing countries
Ombelet, Willem; Cooke, Ian; Dyer, Silke; Serour, Gamal; Devroey, Paul
2008-01-01
BACKGROUND Worldwide more than 70 million couples suffer from infertility, the majority being residents of developing countries. Negative consequences of childlessness are experienced to a greater degree in developing countries when compared with Western societies. Bilateral tubal occlusion due to sexually transmitted diseases and pregnancy-related infections is the most common cause of infertility in developing countries, a condition that is potentially treatable with assisted reproductive technologies (ART). New reproductive technologies are either unavailable or very costly in developing countries. This review provides a comprehensive survey of all important papers on the issue of infertility in developing countries. METHODS Medline, PubMed, Excerpta Medica and EMBASE searches identified relevant papers published between 1978 and 2007 and the keywords used were the combinations of ‘affordable, assisted reproduction, ART, developing countries, health services, infertility, IVF, simplified methods, traditional health care'. RESULTS The exact prevalence of infertility in developing countries is unknown due to a lack of registration and well-performed studies. On the other hand, the implementation of appropriate infertility treatment is currently not a main goal for most international non-profit organizations. Keystones in the successful implementation of infertility care in low-resource settings include simplification of diagnostic and ART procedures, minimizing the complication rate of interventions, providing training-courses for health-care workers and incorporating infertility treatment into sexual and reproductive health-care programmes. CONCLUSIONS Although recognizing the importance of education and prevention, we believe that for the reasons of social justice, infertility treatment in developing countries requires greater attention at National and International levels. PMID:18820005
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Institutional and societal innovations in information technology for developing countries
James, M.J.
2012-01-01
Innovation in the developed countries is heavily based on R&D and is closely related to income, skills and infrastructure in those countries. Little is geared towards IT problems of poor countries. This technology does not suit the incomes, skills and so on of poor countries. Fortunately another
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Obesity among schoolchildren in developing countries.
Galal, Osman M; Hulett, Judie
2005-06-01
The threat of worldwide obesity in children is a reality and has become pandemic. Previously a concern of only developed countries, rapid, escalating rates of overweight children now dominate the public health concerns of middle-and low-income nations as well. There are, of course, many influences that have literally shaped the global population, but there is also a recent observable pattern that is shared by those developing countries with increasingly obese children: a grand structural shift in diet and activity levels on every continent and in every region has occurred in the last quarter century, accompanied by rising rates of obesity. Two central public health concerns drive the need for effective interventions: the immediate health of children and the imminently crushing blow that is coming to health care systems and developing economies due to high rates of chronic disease. In developed nations, the role of gatekeeper has shifted to childcare providers, media, and schools, but in the developing world the traditional role of the mother as home manager has remained intact. Accepting the mother as the primary care provider within the child's nuclear environment places the mother as the guardian of the family's resources, which may be a viable alternative to the types of health-promotion efforts found in past ineffective models.
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Vaccine procurement and self-sufficiency in developing countries.
Woodle, D
2000-06-01
This paper discusses the movement toward self-sufficiency in vaccine supply in developing countries (and countries in transition to new economic and political systems) and explains special supply concerns about vaccine as a product class. It traces some history of donor support and programmes aimed at self-financing, then continues with a discussion about self-sufficiency in terms of institutional capacity building. A number of deficiencies commonly found in vaccine procurement and supply in low- and middle-income countries are characterized, and institutional strengthening with procurement technical assistance is described. The paper also provides information about a vaccine procurement manual being developed by the United States Agency for International Development (USAID) and the World Health Organization (WHO) for use in this environment. Two brief case studies are included to illustrate the spectrum of existing capabilities and different approaches to technical assistance aimed at developing or improving vaccine procurement capability. In conclusion, the paper discusses the special nature of vaccine and issues surrounding potential integration and decentralization of vaccine supply systems as part of health sector reform.
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Management of diagnostic x-ray radiation in developing countries
International Nuclear Information System (INIS)
Date, T.
2000-01-01
The purpose of this study is to provide a simple, inexpensive, and effective method to prevent the scattering of x-ray radiation by using a lead apron in the x-ray rooms of developing countries. In developed countries, the scattering of x-ray radiation among patients and radiographers in diagnostic x-ray rooms has been minimized by various methods. However, in some developing countries, scattered x-ray radiation has not yet been adequately contained. The policy of As Law As Reasonably Achievable (ALARA) requires that patients who are waiting for their examinations must be protected from scattered x-ray radiation. However, from the author's experience, protection from scattered x-ray radiation in x-ray rooms is often insufficient in developing countries. In addition, major public hospitals in big cities are overwhelmed with patients because radiology resources in developing countries are concentrated in the big cities. Moreover, the situation is made worse by short working hours in public hospitals. Hours from 10 a.m. to 3 p.m. are typical. Because of the circumstances, radiographers, who are in a rush to finish all of the examinations within their normal working hours, sometimes allow patients to enter the x-ray rooms while they are waiting for their examinations. Chest and abdominal x-rays are the most common kinds of diagnostic x-ray examination in developing countries. Thus, in this study, anthropomorphic chest and abdominal phantoms were x-rayed for measuring the scattered x-ray radiation with and without protection using a 0.25mmPb lead apron at specific points from the anthropomorphic phantoms in the x-ray room. The lead apron was hung on a mobile apron-hanger and placed next to the anthropomorphic phantom. The scattered radiation dosimetry for chest x-rays proves that this simple method reduces scattered x-ray radiation to 15% at one-meter point and to almost 0% at the two-meter point from the anthropomorphic phantom in the x-ray room. Lead aprons are
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The nuclear power development program of south-east asian countries
International Nuclear Information System (INIS)
Yang, Maeng Ho; Lee, Tae Jun; Lee, Byung Jun
1996-08-01
The objective of this study is to investigate the status of nuclear policy environments and nuclear power programmes of South-east Asian countries which are emerging as major markets in the international nuclear industry. To do this, the study investigated seven South-east Asian countries which are especially expected to strengthen nuclear cooperation with our country : China, Indonesia, Thailand, Malaysia, Vietnam, India and the Philippines. Considering the above, the study concentrated upon the status and the environment of nuclear development, as well as its planning and regulatory structure including energy resource environments, energy development policy and planning, and the major problems in nuclear power development encountered by those counties. This study could be used to develop the national policy of nuclear technological cooperation and nuclear business with South-east Asian countries, which will be expected to develop active nuclear power programmes int eh future. 41 tabs., 9 figs., 49 refs. (Author)
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The nuclear power development program of south-east asian countries
Energy Technology Data Exchange (ETDEWEB)
Yang, Maeng Ho; Lee, Tae Jun; Lee, Byung Jun [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)
1996-08-01
The objective of this study is to investigate the status of nuclear policy environments and nuclear power programmes of South-east Asian countries which are emerging as major markets in the international nuclear industry. To do this, the study investigated seven South-east Asian countries which are especially expected to strengthen nuclear cooperation with our country : China, Indonesia, Thailand, Malaysia, Vietnam, India and the Philippines. Considering the above, the study concentrated upon the status and the environment of nuclear development, as well as its planning and regulatory structure including energy resource environments, energy development policy and planning, and the major problems in nuclear power development encountered by those counties. This study could be used to develop the national policy of nuclear technological cooperation and nuclear business with South-east Asian countries, which will be expected to develop active nuclear power programmes int eh future. 41 tabs., 9 figs., 49 refs. (Author).
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Reactor physics needs in developing countries
International Nuclear Information System (INIS)
Solanilla, R.
1980-01-01
The aim of this paper the identification of needs on Reactor Physics in developing countries embarked in the installation and later on in the operation of Commercial Nuclear Power Plants. In this context the main task of Reactor Physics should be focused in the application of Physical models with inclusion of thermohydraulic process to solve the various realistic problems which appear to ensure a safe, economical and reliable core design and reactor operation. The first part of the paper deals with the scope of Reactor Physics and its interrelation with other disciplines as seen from the view point of developing countries possibilities. Needs requiring a quick response, i.e., those demands coming during the development of a specific Nuclear Power Plant Project, are summarized in the second part of the lecture. Plant startup has been chosen as reference to separate two categories of requirements: Requirements prior to startup phase include reactor core verification, licensing aspects review and study of fuel utilization alternatives; whereas the period during and after startup mainly embraces codes checkup and normalization, core follow-up and long term prediction
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Martinsen, Lene; Ottersen, Trygve; Dieleman, Joseph L; Hessel, Philipp; Kinge, Jonas Minet; Skirbekk, Vegard
2018-01-01
Per capita allocation of overall development assistance has been shown to be biased towards countries with lower population size, meaning funders tend to provide proportionally less development assistance to countries with large populations. Individuals that happen to be part of large populations therefore tend to receive less assistance. However, no study has investigated whether this is also true regarding development assistance for health. We examined whether this so-called 'small-country bias' exists in the health aid sector. We analysed the effect of a country's population size on the receipt of development assistance for health per capita (in 2015 US$) among 143 countries over the period 1990-2014. Explanatory variables shown to be associated with receipt of development assistance for health were included: gross domestic product per capita, burden of disease, under-5 mortality rate, maternal mortality ratio, vaccination coverage (diphtheria, tetanus and pertussis) and fertility rate. We used the within-between regression analysis, popularised by Mundluck, as well as a number of robustness tests, including ordinary least squares, random-effects and fixed-effects regressions. Our results suggest there exists significant negative effect of population size on the amount of development assistance for health per capita countries received. According to the within-between estimator, a 1% larger population size is associated with a 0.4% lower per capita development assistance for health between countries (-0.37, 95% CI -0.45 to -0.28), and 2.3% lower per capita development assistance for health within countries (-2.29, 95% CI -3.86 to -0.72). Our findings support the hypothesis that small-country bias exists within international health aid, as has been previously documented for aid in general. In a rapidly changing landscape of global health and development, the inclusion of population size in allocation decisions should be challenged on the basis of equitable
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Nuclear Fuel Cycle Strategy For Developing Countries
International Nuclear Information System (INIS)
Kim, Chang Hyo
1987-01-01
The world's uranium market is very uncertain at the moment while other front-end fuel cycle services including enrichment show a surplus of supply. Therefore, a current concern of developing countries is how to assure a long-term stable supply of uranium, so far as front-end fuel cycle operation is concerned. So, as for the front-end fuel cycle strategy, I would like to comment only on uranium procurement strategy. I imagine that you are familiar with, yet let me begin my talk by having a look at, the nuclear power development program and current status of fuel cycle technology of developing countries. It is a nice thing to achieve the full domestic control of fuel cycle operation. The surest way to do so is localization of related technology. Nevertheless, developing at a time due to enormous capital requirements, not to mention the non-proliferation restrictions. Therefore, the important which technology to localize prior to other technology and how to implement. The non-proliferation restriction excludes the enrichment and reprocessing technology for the time being. As for the remaining technology the balance between the capital costs and benefits must dictate the determination of the priority as mentioned previously. As a means to reduce the commercial risk and heavy financial burdens, the multi-national joint venture of concerned countries is desirable in implementing the localization projects
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Energy Technology Data Exchange (ETDEWEB)
NONE
2003-09-15
This report for the International Energy Agency (IEA) made by Task 9 of the Photovoltaic Power Systems (PVPS) programme takes a look at the institutional framework and financial instruments necessary for PV deployment in developing countries. This guide describes the institutional and financial aspects that need to be addressed to ensure that a long term sustainable (and profitable) PV market is established in developing countries. The guide details main fundamental functions that need to be performed such as the agents needed to perform the functions and their differing roles within the framework, the relationships between these agents and the financial instruments available. It is stated that the majority of the aspects recommended in this guide can be adopted to two main PV deployment models: direct sales and rural electrification and development programmes. It is noted that both approaches will have to be tailored and adapted to local conditions.
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Climate change and developing country interests
DEFF Research Database (Denmark)
Arndt, Channing; Chinowsky, Paul; Fant, Charles
We consider the interplay of climate change impacts, global mitigation policies, and the interests of developing countries to 2050. Focusing on Malawi, Mozambique, and Zambia, we employ a structural approach to biophysical and economic modeling that incorporates climate uncertainty and allows for...
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Dengue serotype immune-interactions and their consequences for vaccine impact predictions
Directory of Open Access Journals (Sweden)
José Lourenço
2016-09-01
Full Text Available Dengue is one of the most important and wide-spread viral infections affecting human populations. The last few decades have seen a dramatic increase in the global burden of dengue, with the virus now being endemic or near-endemic in over 100 countries world-wide. A recombinant tetravalent vaccine candidate (CYD-TDV has recently completed Phase III clinical efficacy trials in South East Asia and Latin America and has been licensed for use in several countries. The trial results showed moderate-to-high efficacies in protection against clinical symptoms and hospitalisation but with so far unknown effects on transmission and infections per se. Model-based predictions about the vaccine's short- or long-term impact on the burden of dengue are therefore subject to a considerable degree of uncertainty. Furthermore, different immune interactions between dengue's serotypes have frequently been evoked by modelling studies to underlie dengue's oscillatory dynamics in disease incidence and serotype prevalence. Here we show how model assumptions regarding immune interactions in the form of antibody-dependent enhancement, temporary cross-immunity and the number of infections required to develop full immunity can significantly affect the predicted outcome of a dengue vaccination campaign. Our results thus re-emphasise the important gap in our current knowledge concerning the effects of previous exposure on subsequent dengue infections and further suggest that intervention impact studies should be critically evaluated by their underlying assumptions about serotype immune-interactions.
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Status consumption and poverty in developing countries
van Kempen, L.A.C.M.
2005-01-01
This thesis investigates the scope, nature and welfare effects of status consumption by the poor in developing countries, a phenomenon that is virtually unexplored in the development economics literature. It addresses questions such as: why do the poor buy status-intensive goods, while they suffer
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Helminths in the gastrointestinal tract as modulators of immunity and pathology.
Varyani, Fumi; Fleming, John O; Maizels, Rick M
2017-06-01
Helminth parasites are highly prevalent in many low- and middle-income countries, in which inflammatory bowel disease and other immunopathologies are less frequent than in the developed world. Many of the most common helminths establish themselves in the gastrointestinal tract and can exert counter-inflammatory influences on the host immune system. For these reasons, interest has arisen as to how parasites may ameliorate intestinal inflammation and whether these organisms, or products they release, could offer future therapies for immune disorders. In this review, we discuss interactions between helminth parasites and the mucosal immune system, as well as the progress being made toward identifying mechanisms and molecular mediators through which it may be possible to attenuate pathology in the intestinal tract. Copyright © 2017 the American Physiological Society.
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Space technology transfer to developing countries: opportunities and difficulties
Leloglu, U. M.; Kocaoglan, E.
Space technology, with its implications on science, economy and security, is mostly chosen as one of the priority areas for technological development by developing countries. Most nations aspiring to begin playing in the space league prefer technology transfer programs as a first step. Decreasing initial costs by small satellite technology made this affordable for many countries. However, there is a long way from this first step to establishment of a reliable space industry that can both survive in the long term with limited financial support from the government and meet national needs. This is especially difficult when major defense companies of industrialized countries are merging to sustain their competitiveness. The prerequisites for the success are implementation of a well-planned space program and existence of industrialization that can support basic testing and manufacturing activities and supply qualified manpower. In this study, the difficulties to be negotiated and the vicious circles to be broken for latecomers, that is, developing countries that invest on space technologies are discussed. Especially, difficulties in the technology transfer process itself, brain drain from developing countries to industrialized countries, strong competition from big space companies for domestic needs, costs of establishing and maintaining an infrastructure necessary for manufacturing and testing activities, and finally, the impact of export control will be emphasized. We will also try to address how and to what extent collaboration can solve or minimize these problems. In discussing the ideas mentioned above, lessons learned from the BILSAT Project, a technology transfer program from the UK, will be referred.
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Jafari, Mostafa; Zarghami, Hamid Reza
2016-07-01
This paper investigates the global nanotechnology and nanoscience (NN) indicators in a developmental context, during three 5-year periods from 2000 to 2014. Through bibliometric analyses of the longitudinal data from well-known databases, the growth patterns of NN articles and patents were investigated. Furthermore, the causal relationships among these indicators and some characteristics of the 105 countries studied were examined using regression and correlation analyses leading to the identification of the top 20 "science and innovation giants," in terms of all indicators, as well as the existence of significant, yet different, correlations among the indicators in developing and developed countries. In general, China's growth rate (GR) in NN publications was found to surpass USA, from 2010 to 2014, leading to a change in the ranking of the top countries and moving China, with about 25 % of world's NN articles, to top. A different trend was distinguished for patents in the area of nanotechnology, where USA, as the origin of over half of the world's granted patents, has been the undisputed leader. The shares of developing countries (i.e., the percent ratios of the number of nanotech patents granted to the citizens of developing countries over the total number of nanotech patents granted worldwide) was found to be incompatible with the countries' shares in the total NN articles, indicating a poor correlation between the two factors. However, developing countries were found to be superior in the GR of both NN articles and patents. Finally, the top countries identified can be regarded as suitable for comparative studies, and benchmarking by researchers and policy makers.
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Financing the energy sector in developing countries: context and overview
International Nuclear Information System (INIS)
Dunkerley, Joy.
1995-01-01
Traditional 'business as usual' financing methods will no longer be adequate to meet the unprecedented demands for capital to finance energy sector expansion in the developing countries. In recognition, many countries are opening up their power sectors to private investment, initially through the establishment of independent power projects, but in some cases through sector privatization. Project financing has many advantages, but further sectoral reorganization, including tariff reform, will be needed to attract resources on the scale required, especially from domestic investors. In oil and gas, in contrast to power, private capital from the international oil companies has always played a major role in the developing countries. However, sharply increasing investment requirements require a growing role for external finance. There should, in principle, be no shortage of investible funds to finance energy sector expansion in developing countries so long as host countries establish conditions which are attractive to private investors. The augmented role of private finance requires a continuing, if different, role for the public sector in both host countries and official aid agencies. (author)
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Influence Of Tax Havens On The Functioning Of Developing And Developed Countries
Directory of Open Access Journals (Sweden)
Arkadiusz Nawrocki
2017-12-01
Full Text Available This article discusses the impact of tax havens on developing and developed countries. Economic research in this area has proved that tax havens not only play a key role on the international capital market, but above all are responsible for the internationalisation of economic activity on a global scale. Representatives of theory, practitioners and regulators for decades conducted research related to the assessment of the impact of tax havens on countries with high taxes in terms of the erosion of their base. The obtained results clearly show that these countries face a significant decline in income, however, some researchers (especially Hines show that there are positive side effects of this process indicating the creation of a new model in the global financial symbiosis.
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Promotion and financing of nuclear power programmes in developing countries
International Nuclear Information System (INIS)
1987-01-01
The Director General of the International Atomic Energy Agency established in February 1986 a Senior Expert Group (SEG) on Mechanisms to Assist Developing Countries in the Promotion and Financing of Nuclear Power Programmes, which was asked: (a) To identify and analyse the problems of and constraints on nuclear power introduction/expansion in developing countries, with particular attention being paid to the problems of financing nuclear power projects; (b) To study mechanisms for dealing with the identified problems and constraints in order to assist developing countries with the promotion and financing of their nuclear power programmes, and to determine the role of the IAEA in this context. This report summarizes the Senior Expert Group's study. It also presents a number of recommendations on mechanisms to assist developing countries in promoting and financing their nuclear power programmes. 1 fig., 3 tabs
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Shifting the Climate Finance Paradigm: Nine Key Challenges for Developed Countries
Energy Technology Data Exchange (ETDEWEB)
Curtin, Joseph
2013-03-13
In 2009, developed countries committed to part-funding the cost of adapting to the impacts of climate change and of low carbon development in developing countries. From 2010 to 2012, fast start finance began to flow from developed country exchequers. However, the climate finance paradigm is now shifting. A transition from loans and grants provided from scarce exchequer resources to innovative instruments for leveraging private capital and mitigating investment risk is required in the coming period. But what are the implications for developed countries? This policy brief explores the policy context defining the current climate finance debate; examines the extent to which commitments have been met; and identifies nine key challenges for developed countries as they enter the new climate finance paradigm, drawing on the lessons of the fast start finance period. This is the second in a series of Environment Nexus policy briefs by leading experts in the fields of agriculture, energy, climate change and water.
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Comparative evaluation of nuclear power in developing countries
International Nuclear Information System (INIS)
Obermair, G.M.
1990-01-01
Even in those developing countries where nuclear power is technically feasible and competitive against the alternatives, most other factors weigh heavily against the nuclear path for the next decades. This does not mean that nuclear power should be completely ruled out in the longer run. At the moment several problems of nuclear power, in particular its follow-up effects and costs, are not really solved. The results of present efforts toward their solution can probably only be judged in the 1990s. It is not now clear whether the total outcome of nuclear energy is positive, even in the industrialized countries. Any country with an evenly developed technical infrastructure and a sufficiently broad basis of intellectual and technical skills will be able to acquire the specialized nuclear knowhow within a few years. For the meantime,in the opinion of the author, national and international efforts should establish technical school and faculties, study groups should be set up that analyse the energy situation in the individual countries in depth and watch international developments in the nuclear sector. A thorough knowledge of the unresolved problems will prevent their being ignored in the intellectual fascination and political challenge of nuclear power. (author). 11 refs., 3 tabs
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Energy technology transfer to developing countries
International Nuclear Information System (INIS)
Butera, F.; Farinelli, U.
1992-01-01
With the use of critical analyses of some examples of technology transfer by industrialized to third world countries, this paper illustrates the importance, in technology transfer, of giving due consideration to the specific social and marketing contexts of the targeted developing country and its physical and financial capability to acquire all the technology necessary to make the total realization of a desired industrial scheme feasible from the economic, technical and social points of view. It also indicates that the most effective transfers are those in which efforts are made to optimize local work force learning levels, process scheme efficiency and cost through the careful integration of innovative with conventional technologies
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Housing policies in developing countries: Microfinance
Smets, P.G.S.M.; Smith, S.J.; Elsinga, M.; O’Mahony, L.H.; Ong, S.E.; Wachter, S.; Wood, G.
2012-01-01
Shelter is a basic human need for which financial means are required. Poorer sections of society face difficulties in accessing and coping with conventional mortgage finance and are better assisted with housing microfinance. This enables the poor, especially in 'developing' countries to build their
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Institutional Structure and International Competitiveness Relationship in Developed Countries
Directory of Open Access Journals (Sweden)
Aynur Yıldırım
2016-06-01
Full Text Available This study analyzes the effects of institutional structure on the international competitiveness of developed countries econometrically by employing a “Panel Data Analysis” with a sample of 21 developed countries and 23 institutional variables for the period 2000-2011. The results of the analysis indicate that while judicial independence, protection of intellectual property rights, integrity of the juridical system, marginal tax, political freedoms, black market exchange rate, restrictions on foreign investment, private sector’s share in the banking system, hiring-minimum wage, and hiring-dismissal have a positive effect; the nature of legal arrangements, government spending, transfers and subsidies, civil liberties, tariffs, regulations regarding trade barriers, collective bargaining, and military tutelage have a negative effect on the international competitiveness of developed countries.
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Energy Security and Renewable Energy in Least Developed Countries
International Nuclear Information System (INIS)
Wohlgemuth, N.
2006-01-01
The Programme of Action for the Least Developed Countries (UN, 2001) states: The levels of production and consumption of energy in the majority of Least Developed Countries (LDCs) are inadequate and unstable. This clearly indicates a situation of energy insecurity. Starting from an encompassing definition of energy security (a country's ability to expand and optimise its energy resource portfolio and achieve a level of services that will sustain economic growth and poverty reduction), it becomes quickly clear that energy security in LDCs is a complex topic with numerous interlinkages to other sustainable development objectives. This paper attempts to give an overview of issues related to energy security in LDCs by focusing on the role renewable energy can play in that context.(author)
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International Nuclear Information System (INIS)
Mahadevan, Renuka; Asafu-Adjaye, John
2007-01-01
This paper reinvestigates the energy consumption-GDP growth nexus in a panel error correction model using data on 20 net energy importers and exporters from 1971 to 2002. Among the energy exporters, there was bidirectional causality between economic growth and energy consumption in the developed countries in both the short and long run, while in the developing countries energy consumption stimulates growth only in the short run. The former result is also found for energy importers and the latter result exists only for the developed countries within this category. In addition, compared to the developing countries, the developed countries' elasticity response in terms of economic growth from an increase in energy consumption is larger although its income elasticity is lower and less than unitary. Lastly, the implications for energy policy calling for a more holistic approach are discussed
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Problems of Foreign Economic Relations Development of Ural Regions with BRICS Countries
Directory of Open Access Journals (Sweden)
Mikhail Ivanovich Maslennikov
2015-06-01
Full Text Available In the article, the basic vocabulary of BRICS countries, its regional tendencies of business development, and its share taken in the foreign-economic activity are analyzed. Contribution of different foreign trade fields of regions into economic development is revealed. Indicators of development levels of external economic links are reviewed. Alternative options of the foreign trade development, expenses and benefits from its reorientation, and the reason of low indicators of development of foreign trade activity of the Ural regions with BRICS countries are evaluated, and measures for their improvement and development are offered. The mechanism and tools of stimulation of foreign economic relations development of regions with BRICS countries are investigated. The internal and external motives and incentives of expansion of these relations are examined. The factors influencing the regional markets development and revealing multidirectional tendencies in activities of business, government, society for development of foreign economic relations of the Ural regions with BRICS countries, and first of all with Brazil, India, China and the Republic of South Africa are investigated. The export-import features of the foreign trade operations with these countries, and also possible ways and the directions of expansion of the prognostics of foreign economic relations in the conditions of toughening and restriction of similar operations and financial sources from the developed countries, first of all the USA and EU countries are represented. Author examines the reasons and scenario, problems and difficulties for the country and the Ural regions in refocusing of international economic relation from Western Europe to the South-East Asia countries. Real opportunities of participation of regions of the country in the import substitution and development of own resource and production base are analyzed. The research is focused on analysis of international economic
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Sustainable development and public health: rating European countries
Directory of Open Access Journals (Sweden)
Seke Kristina
2013-01-01
Full Text Available Abstract Background Sustainable development and public health quite strongly correlate, being connected and conditioned by one another. This paper therein attempts to offer a representation of Europe’s current situation of sustainable development in the area of public health. Methods A dataset on sustainable development in the area of public health consisting of 31 European countries (formally proposed by the European Union Commission and EUROSTAT has been used in this paper in order to evaluate said issue for the countries listed thereof. A statistical method which synthesizes several indicators into one quantitative indicator has also been utilized. Furthermore, the applied method offers the possibility to obtain an optimal set of variables for future studies of the problem, as well as for the possible development of indicators. Results According to the results obtained, Norway and Iceland are the two foremost European countries regarding sustainable development in the area of public health, whereas Romania, Lithuania, and Latvia, some of the European Union’s newest Member States, rank lowest. The results also demonstrate that the most significant variables (more than 80% in rating countries are found to be “healthy life years at birth, females” (r2 = 0.880, “healthy life years at birth, males” (r2 = 0.864, “death rate due to chronic diseases, males” (r2 = 0.850, and “healthy life years, 65, females” (r2 = 0.844. Conclusions Based on the results of this paper, public health represents a precondition for sustainable development, which should be continuously invested in and improved. After the assessment of the dataset, proposed by EUROSTAT in order to evaluate progress towards the agreed goals of the EU Sustainable Development Strategy (SDS, this paper offers an improved set of variables, which it is hoped, may initiate further studies concerning this problem.
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Sustainable development and public health: rating European countries.
Seke, Kristina; Petrovic, Natasa; Jeremic, Veljko; Vukmirovic, Jovanka; Kilibarda, Biljana; Martic, Milan
2013-01-28
Sustainable development and public health quite strongly correlate, being connected and conditioned by one another. This paper therein attempts to offer a representation of Europe's current situation of sustainable development in the area of public health. A dataset on sustainable development in the area of public health consisting of 31 European countries (formally proposed by the European Union Commission and EUROSTAT) has been used in this paper in order to evaluate said issue for the countries listed thereof. A statistical method which synthesizes several indicators into one quantitative indicator has also been utilized. Furthermore, the applied method offers the possibility to obtain an optimal set of variables for future studies of the problem, as well as for the possible development of indicators. According to the results obtained, Norway and Iceland are the two foremost European countries regarding sustainable development in the area of public health, whereas Romania, Lithuania, and Latvia, some of the European Union's newest Member States, rank lowest. The results also demonstrate that the most significant variables (more than 80%) in rating countries are found to be "healthy life years at birth, females" (r2 = 0.880), "healthy life years at birth, males" (r2 = 0.864), "death rate due to chronic diseases, males" (r2 = 0.850), and "healthy life years, 65, females" (r2 = 0.844). Based on the results of this paper, public health represents a precondition for sustainable development, which should be continuously invested in and improved.After the assessment of the dataset, proposed by EUROSTAT in order to evaluate progress towards the agreed goals of the EU Sustainable Development Strategy (SDS), this paper offers an improved set of variables, which it is hoped, may initiate further studies concerning this problem.
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Food aid to developing countries: a survey
Energy Technology Data Exchange (ETDEWEB)
Maxwell, S J; Singer, H W
1979-03-01
Food air currently constitutes nearly 15% of official development assistance and hence has considerable potential as a stimulant to growth in less-developed countries (LDCs). This paper reviews the evidence on the impact of food aid on growth and its associated factors. While recognizing that the use of food aid is influenced by a constellation of interests in recipient and donor countries, it identifies a set of guiding principles for maximizing the effectiveness of food aid. These include the need for food (relative to other development needs), its level of substitutability with commercial imports, its incorporation in a poverty-oriented development plan, its guaranteed availability and its complementarity with financial aid. Current food air programs recognize the relevance of some of these principles - e.g. the criteria of necessity - but ignore others - notably the need to situate food aid in a comprehensive plan for improving patterns of income distribution in LDCs. 203 notes, 203 references.
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Radioimmunoassay for human health in developing countries
International Nuclear Information System (INIS)
Piyasena, R.D.; Airey, P.L.; Ganatra, R.D.; Nofal, M.
1989-01-01
Since first introduced in the early 1960s, radioimmunoassay (RIA) has gained wide acceptance as an analytical method adopted by an increasing number of developing countries as an appropriate technology that can be managed within the capabilities of local infrastructures. An informed estimate would be that there are, at present, more than 500 hospitals, university, or other laboratories in the developing world engaged in RIA on some scale. In the developing world, RIA is used primarily for patient management, but research activity is also increasing as expertise and resources improve. The majority of patient samples processed are in relation to thyroid disorders. However, the technique also is used widely in the investigation of other endocrine conditions and public health problems. Some developing countries have gained the capability to perform radioisotopic microassays in areas of clinical and research importance such as steroid receptor quantification in breast tissue; diagnosis of bacterial and parasitic disorders; investigation of infertility and sterility; narcotic drug abuse; and organ transplantation. 1 fig
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Nuclear trade between developing countries
International Nuclear Information System (INIS)
Stahl, K.
1990-01-01
The analysis of nuclear south-south cooperation is based on the evaluation of official documents (the texts of laws, of contracts for nuclear cooperation treaties, safeguard treaties, official government policy speeches etc.). These data were supplemented by numerous interviews with representatives of atomic energy authorities, foreign ministries, nuclear industries, members of parliament, representatives of the nuclear energy opposition movement and military representatives in the three states and by interviews with representatives of the IAEO and OPANAL in Mexico. The study deals with each country in turn: Chapter 2 gives an overview of the Indian nuclear energy programme and India's nuclear export activity and export policy. Chapter 3 analyzes Brazil's nuclear energy policy and Brazilian export capacities, exports and export policy in the nuclear sector. Chapter 4 looks at the development of the Argentinian nuclear energy programme and the crisis in it, at Argentina's nuclear export activities and its export policy and technology transfer policy in this field. Chapter 5 analyzes separately relations between Argentina and Brazil on nuclear cooperation, since they differ considerably from the two countries' relations with other Third World countries on this topic. The appendix documents the most important contractual agreements and government policy declarations on nuclear cooperation between the two states. (orig.) [de
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Nanotechnologies risk assessment: a perspective from developing countries
CSIR Research Space (South Africa)
Musee, N
2009-09-01
Full Text Available chemicals in these states: the unique challenges of nanotechnologies from a waste perspective are modeled to develop scenarios of likely impacts to the developing countries. Both qualitative and quantitative risk assessment approaches were developed...
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Nash, Michael J.; Frank, Daniel N.; Friedman, Jacob E.
2017-01-01
The developing infant gut microbiome affects metabolism, maturation of the gastrointestinal tract, immune system function, and brain development. Initial seeding of the neonatal microbiota occurs through maternal and environmental contact. Maternal diet, antibiotic use, and cesarean section alter the offspring microbiota composition, at least temporarily. Nutrients are thought to regulate initial perinatal microbial colonization, a paradigm known as the “Restaurant” hypothesis. This hypothesis proposes that early nutritional stresses alter both the initial colonizing bacteria and the development of signaling pathways controlled by microbial mediators. These stresses fine-tune the immune system and metabolic homeostasis in early life, potentially setting the stage for long-term metabolic and immune health. Dysbiosis, an imbalance or a maladaptation in the microbiota, can be caused by several factors including dietary alterations and antibiotics. Dysbiosis can alter biological processes in the gut and in tissues and organs throughout the body. Misregulated development and activity of both the innate and adaptive immune systems, driven by early dysbiosis, could have long-lasting pathologic consequences such as increased autoimmunity, increased adiposity, and non-alcoholic fatty liver disease (NAFLD). This review will focus on factors during pregnancy and the neonatal period that impact a neonate’s gut microbiome, as well as the mechanisms and possible links from early infancy that can drive increased risk for diseases including obesity and NAFLD. The complex pathways that connect diet, the microbiota, immune system development, and metabolism, particularly in early life, present exciting new frontiers for biomedical research. PMID:29326657
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Luzze, Henry; Badiane, Ousseynou; Mamadou Ndiaye, El Hadji; Ndiaye, Annette Seck; Atuhaire, Brian; Atuhebwe, Phionah; Guinot, Phillippe; Fry Sosne, Erin; Gueye, Abdoulaye
2017-04-19
As immunization programs around the world undergo rapid change and expansion, supply chain and logistics systems have become strained, making it increasingly challenging for national public health systems to provide reliable, safe, and efficient access to vaccines. Governments and immunization partners have been aware of this problem for several years, and in 2010, the World Health Organization (WHO) launched the Effective Vaccine Management (EVM) process to help countries identify shortcomings in their immunization supply chains and develop plans for systematic improvement. EVM improvement plans now exist in all Gavi-eligible countries plus many middle- and upper-income countries; however, implementation has been slow and in many cases fraught with financial, managerial, structural, and political roadblocks. Recognizing that significant change of any kind requires a supportive policy environment and strong leadership, PATH began working in Uganda and Senegal to landscape the policy environment around immunization and identify relevant policies, administrative and technical roles and responsibilities, and other issues that may be affecting the supply chain for immunization. The policy landscape assessments included a desk review and a series of structured, in-depth interviews with key international, national, and local stakeholders. The findings highlighted a number of critical issues and challenges in both countries that may be preventing supply chains from functioning optimally. These challenges include a need for better coordination and planning between immunization programs and supply chain managers; the need for sufficient, timely and reliable financing for all aspects of immunization programs; the need for high-level managers trained in immunization supply chain management; and an urgent need for better, more timely data for decision-making. Overcoming these challenges will require the involvement of high-level political actors-including ministers of health
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Reproductive rights approach to reproductive health in developing countries
Directory of Open Access Journals (Sweden)
Vijayan K. Pillai
2011-12-01
Full Text Available Research on reproductive health in developing countries focuses mostly on the role of economic development on various components of reproductive health. Cross-sectional and empirical research studies in particular on the effects of non-economic factors such as reproductive rights remain few and far between.This study investigates the influence of two components of an empowerment strategy, gender equality, and reproductive rights on women's reproductive health in developing countries. The empowerment strategy for improving reproductive health is theoretically situated on a number of background factors such as economic and social development.Cross-national socioeconomic and demographic data from a number of international organizations on 142 developing countries are used to test a model of reproductive rights and reproductive health.The findings suggest that both economic and democratic development have significant positive effects on levels of gender equality. The level of social development plays a prominent role in promoting reproductive rights. It is found that reproductive rights channel the influences of social structural factors and gender equality on reproductive health.
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Reproductive rights approach to reproductive health in developing countries.
Pillai, Vijayan K; Gupta, Rashmi
2011-01-01
Research on reproductive health in developing countries focuses mostly on the role of economic development on various components of reproductive health. Cross-sectional and empirical research studies in particular on the effects of non-economic factors such as reproductive rights remain few and far between. This study investigates the influence of two components of an empowerment strategy, gender equality, and reproductive rights on women's reproductive health in developing countries. The empowerment strategy for improving reproductive health is theoretically situated on a number of background factors such as economic and social development. Cross-national socioeconomic and demographic data from a number of international organizations on 142 developing countries are used to test a model of reproductive rights and reproductive health. The findings suggest that both economic and democratic development have significant positive effects on levels of gender equality. The level of social development plays a prominent role in promoting reproductive rights. It is found that reproductive rights channel the influences of social structural factors and gender equality on reproductive health.
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HIS priorities in developing countries.
Amado Espinosa, L
1995-04-01
Looking for a solution to fulfill the requirements that the new global economical system demands, developing countries face a reality of poor communications infrastructure, a delay in applying information technology to the organizations, and a semi-closed political system avoiding the necessary reforms. HIS technology has been developed more for transactional purposes on mini and mainframe platforms. Administrative modules are the most frequently observed and physicians are now requiring more support for their activities. The second information systems generation will take advantage of PC technology, client-server models and telecommunications to achieve integration. International organizations, academic and industrial, public and private, will play a major role to transfer technology and to develop this area.
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Considerations on technology transfer process in nuclear power industry for developing countries
International Nuclear Information System (INIS)
Castro, I.P.
2000-01-01
Nuclear know-how cannot possibly be developed globally in developing countries, so technology transfer is the only conceivable way to make nuclear power accessible to these countries. Technology transfer process accounts for three mayor steps, namely acquisition, assimilation and diffusion, so a serious nuclear power program should comprise all of them. Substantial national efforts should be made by developing countries in financial, industrial, scientific, organizational and many other aspects in order to succeed a profitable technology transfer, but developing countries cannot make it by themselves. Finance is the biggest problem for developing world nuclear power projects. Human resource qualification is another important aspect of the nuclear power technology transfer, where technology receptor countries should prepare thousands of professionals in domestic and foreign schools. Challenge for nuclear power deployment is economical, but also social and political. Developed countries should be open to cooperate with developing countries in meeting their needs for nuclear power deployment that should be stimulated and coordinated by an international body which should serve as mediator for nuclear power technology transfer. This process must be carried out on the basis of mutual benefits, in which the developed world can exploit the fast growing market of energy in the developing world, but with the necessary condition of the previous preparation of our countries for this technology transfer. (author)
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Implementing the illicit financial flows agenda: Perspectives from developing countries
Fontana, Alessandra; Hansen-Shino, Kjetil
2012-01-01
While once considered solely a concern of law enforcement agencies; money laundering, tax evasion and secrecy jurisdictions are now perceived as important obstacles to development. Dealing with illicit financial flows is an important aspect of the policy coherence agenda in international development, and developed country governments have made international commitments to tackle the problem Reforms and actions are necessary both in developed and developing countries, and this Brief looks at t...
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Readiness for banking technologies in developing countries
African Journals Online (AJOL)
Professor in the Department of Marketing Management, University of Johannesburg. ... From the organisation's perspective, it has been suggested ... technological readiness of developing countries' consumers, in an urban environment,.
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de Oliveira, Lúcia H; Toscano, Cristiana M; Sanwogou, N Jennifer; Ruiz-Matus, Cuauhtémoc; Tambini, Gina; Roses-Periago, Mirta; Andrus, Jon K
2013-07-02
Countries in Latin America were among the first developing countries to introduce new vaccines, particularly rotavirus (RV) and pneumococcal conjugate vaccines (PCVs), into their national immunization schedules. Experiences and lessons learned from these countries are valuable to donors, immunization partners, and policy makers in other countries wishing to make informed decisions on vaccine introduction. In order to enhance knowledge and promote understanding of the process of new vaccine introduction in the Latin American Region, with particular focus on RV and PCV, we conducted a systematic qualitative assessment. We evaluated the decision-making process, documented the structure in place, and reviewed key factors pertaining to new vaccine introduction. These include country morbidity and mortality data available prior to vaccine introduction, funding sources and mechanisms for vaccine introduction, challenges of implementation, and assessment of vaccine impact. From March 2010 to April 2011, we evaluated a subset of countries that had introduced RV and/or PCV in the past five years through interviews with key informants at the country level and through a systematic review of published data, gray literature, official technical documents, and country-specific health indicators. Countries evaluated were Bolivia, Brazil, Nicaragua, Peru, and Venezuela. In all countries, the potential of new vaccines to reduce mortality, as established by Millennium Development Goal 4, was an important consideration leading to vaccine introduction. Several factors-the availability of funds, the existence of sufficient evidence for vaccine introduction, and the feasibility of sustainable financing-were identified as crucial components of the decision-making process in the countries evaluated. The decision making process regarding new vaccine introduction in the countries evaluated does not follow a systematic approach. Nonetheless, existing evidence on efficacy, potential impact, and
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Development challenges of resource-rich countries: the case of oil ...
African Journals Online (AJOL)
This paper discusses some of the challenges that confront oil-rich developing countries in their development quest. It stresses that one of the surest ways governments in oil-rich developing countries have at their disposal to avoid the so-called curse of oil is through the insulation of fiscal policy from the volatility associated ...
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Insurance market development: An empirical study of African countries
Directory of Open Access Journals (Sweden)
Athenia Bongani Sibindi
2015-12-01
Full Text Available The insurance industry plays a very crucial role in an economy by fostering intermediation and by its mechanism of risk bearing. As such it could be argued that the insurance industry fosters economic growth. In this article we analyse the global insurance market development trends, particularly focusing on Africa. Our sample comprise of the 10 African countries namely—South Africa, Angola, Nigeria, Kenya, Mauritius, Namibia, Algeria, Tunisia, Morocco and Egypt. We employ three insurance market development metrics namely; premium volumes, insurance density and insurance penetrations ratios to establish trends in the level of development of global insurance markets. Our results document that the African countries (excluding South Africa have the least developed insurance markets. For most of the countries in our sample, the non-life insurance industry dominates the life-insurance industry. As such, it is imperative that their respective governments put in place measures that will grow their economies inorder to stimulate the development of insurance markets in Africa.
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Promotion and financing of nuclear power programmes in developing countries
International Nuclear Information System (INIS)
Bennett, L.L.; Skjoeldebrand, R.
1988-01-01
Nuclear power has been introduced only to a small extent in a few developing countries. A group of senior experts conducted a study of the existing constraints on nuclear power in developing countries, the requirements to be met for successful introduction of a nuclear power programme, and mechanisms to assist developing countries in overcoming the identified constraints. Financing represents one (but not the only) major constraint to nuclear power development in developing countries. The present schemes of export credits and commercial financing are seen as not adequately meeting the needs of nuclear power financing in terms of repayment periods and profiles, or in terms of flexibility to meet delays and cost overruns. Innovative and workable arrangements to share the economic and financial risks would be helpful in obtaining financing for a nuclear power project. All possible efforts should be made by all parties involved in the development of nuclear power to reduce as far as possible the uncertainties surrounding the cost and schedule of a nuclear power project, as an essential step to improve the overall climate for financing the project. Government commitment, soundly based and thorough planning, development of qualified manpower and other key infrastructures, and good project management are important mechanisms to achieve greater predictability in project schedule and cost. Technical assistance provided by the IAEA can be very helpful in building these capabilities in developing countries. (author). 1 tab
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Richard, Caroline; Lewis, Erin D; Field, Catherine J
2016-05-01
Long-chain polyunsaturated fatty acids (LCPUFA), especially the balance between arachidonic (AA) and docosahexaenoic (DHA) acids are known to have important immunomodulatory roles during the postnatal period when the immune system is rapidly developing. AA and DHA are required in infant formula in many countries but are optional in North America. The rationale for adding these LCPUFA to full-term formula is based on their presence in breast milk and randomized controlled studies that suggest improved cognitive function in preterm infants, but results are more variable in full-term infants. Recently, the European Food Safety Authority has proposed, based on a lack of functional evidence, that AA is not required in infant formula for full-term infants during the first year of life but DHA should remain mandatory. The purpose of this review is to review the evidence from epidemiological and intervention studies regarding the essentiality of AA and DHA in the postnatal infant and maternal diet (breast-feeding) for the immune system development early in life. Although studies support the essentiality of DHA for the immune system development, more research is needed to rule out the essentiality of AA. Nevertheless, intervention studies have demonstrated improvement in many markers of immune function in infants fed formula supplemented with AA and DHA compared with unsupplemented formula, which appears to consistently result in beneficial health outcomes including reduction in the risk of developing allergic and atopic disease early in life.
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Analysis of Drug Development Paradigms for Immune Checkpoint Inhibitors.
Jardim, Denis L; de Melo Gagliato, Débora; Giles, Francis J; Kurzrock, Razelle
2018-04-15
Immune checkpoint inhibitors have unique toxicities and response kinetics compared with cytotoxic and gene-targeted anticancer agents. We investigated the impact of innovative/accelerated immunotherapy drug development/approval models on the accuracy of safety and efficacy assessments by searching the FDA website. Initial phase I trials for each agent were reviewed and safety and efficacy data compared with that found in later trials leading to regulatory approvals of the same agents. As of June 2017, the FDA approved six checkpoint inhibitors for a variety of cancer types. All checkpoint inhibitors received a priority review status and access to at least two additional FDA special access programs, more often breakthrough therapy designation and accelerated approval. Median clinical development time (investigational new drug application to approval) was 60.77 months [avelumab had the shortest timeline (52.33 months)]. Response rates during early phase I trials (median = 16%) are higher than for phase I trials of other agents (with the exception of gene-targeted agents tested with a biomarker). Doses approved were usually not identical to doses recommended on phase I trials. Approximately 50% of types of immune-related and 43% of types of clinically relevant toxicities from later trials were identified in early-phase trials. Even so, treatment-related mortality remains exceedingly low in later studies (0.33% of patients). In conclusion, efficacy and safety of immune checkpoint inhibitors appear to be reasonably predicted from the dose-finding portion of phase I trials, indicating that the fast-track development of these agents is safe and justified. Clin Cancer Res; 24(8); 1785-94. ©2017 AACR . ©2017 American Association for Cancer Research.
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WTO negotiations on agriculture and developing countries:
Hoda, Anwarul; Gulati, Ashok
2008-01-01
The World Trade Organization’s Doha Round of trade talks has been plagued by a lack of concrete progress toward establishing a fair and harmonious agricultural trading system. Because the results of the Doha Round could have far-reaching implications for the trade and economic prospects of developing countries in the twenty-first century, it is critical for these countries to fully understand the issues involved in the negotiations on agriculture. However, there has been no authoritative an...
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Coping with terms-of-trade shocks in developing countries
Christian Broda; Cedric Tille
2003-01-01
Sharp swings in a developing country's terms of trade, the price of its exports relative to the price of its imports, can seriously disrupt output growth. An analysis of the effects of a decline in export prices in seventy-five developing economies suggests that countries with a flexible exchange rate will experience a much milder contraction in output than their counterparts with fixed exchange rate regimes.
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Water Loss Management: Tools and Methods for Developing Countries
Mutikanga, H.E.
2012-01-01
Water utilities in developing countries are struggling to provide customers with a reliable level of service due to their peculiar water distribution characteristics including poorly zoned networks with irregular supply operating under restricted budgets. These unique conditions demand unique tools and methods for water loss control. Water loss management: Tools and Methods for Developing Countries provide a decision support toolbox (appropriate tools and methodologies) for assessing, quantif...
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Urban bioclimatology in developing countries.
Jauregui, E
1993-11-15
A brief review of the literature on urban human bioclimatology in the tropics is undertaken. Attempts to chart human bioclimatic conditions on the regional/local scale have been made in several developing countries. The effective temperature scheme (with all its limitations) is the one that has been most frequently applied. The possibilities of application of bioclimatic models based on human heat balance for the tropical urban environment are discussed.
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A passive cold storage device economic model to evaluate selected immunization location scenarios.
Norman, Bryan A; Nourollahi, Sevnaz; Chen, Sheng-I; Brown, Shawn T; Claypool, Erin G; Connor, Diana L; Schmitz, Michelle M; Rajgopal, Jayant; Wateska, Angela R; Lee, Bruce Y
2013-10-25
The challenge of keeping vaccines cold at health posts given the unreliability of power sources in many low- and middle-income countries and the expense and maintenance requirements of solar refrigerators has motivated the development of passive cold storage devices (PCDs), containers that keep vaccines cold without using an active energy source. With different PCDs under development, manufacturers, policymakers and funders need guidance on how varying different PCD characteristics may affect the devices' cost and utility. We developed an economic spreadsheet model representing the lowest two levels of a typical Expanded Program on Immunization (EPI) vaccine supply chain: a district store, the immunization locations that the district store serves, and the transport vehicles that operate between the district store and the immunization locations. The model compares the use of three vaccine storage device options [(1) portable PCDs, (2) stationary PCDs, or (3) solar refrigerators] and allows the user to vary different device (e.g., size and cost) and scenario characteristics (e.g., catchment area population size and vaccine schedule). For a sample set of select scenarios and equipment specification, we found the portable PCD to generally be better suited to populations of 5,000 or less. The stationary PCD replenished once per month can be a robust design especially with a 35L capacity and a cost of $2,500 or less. The solar device was generally a reasonable alternative for most of the scenarios explored if the cost was $2,100 or less (including installation). No one device type dominated over all explored circumstances. Therefore, the best device may vary from country-to-country and location-to-location within a country. This study introduces a quantitative model to help guide PCD development. Although our selected set of explored scenarios and device designs was not exhaustive, future explorations can further alter model input values to represent additional scenarios
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Sustainable development of smallholder crop-livestock farming in developing countries
Ates, S.; Cicek, H.; Bell, L. W.; Norman, H. C.; Mayberry, D. E.; Kassam, S.; Hannaway, D. B.; Louhaichi, M.
2018-03-01
Meeting the growing demand for animal-sourced food, prompted by population growth and increases in average per-capita income in low-income countries, is a major challenge. Yet, it also presents significant potential for agricultural growth, economic development, and reduction of poverty in rural areas. The main constraints to livestock producers taking advantage of growing markets include; lack of forage and feed gaps, communal land tenure, limited access to land and water resources, weak institutions, poor infrastructure and environmental degradation. To improve rural livelihood and food security in smallholder crop-livestock farming systems, concurrent work is required to address issues regarding efficiency of production, risk within systems and development of whole value chain systems. This paper provides a review of several forage based-studies in tropical and non-tropical dry areas of the developing countries. A central tenet of this paper is that forages have an essential role in agricultural productivity, environmental sustainability and livestock nutrition in smallholder mixed farming systems.
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The Expanded Program on Immunization in the Americas: a review.
1985-01-01
The basis for the Pan America Health Organization/World Health Organization Expanded Program on Immunization (EPI) is provided by a resolution (WHA27.57) adopted by the World Health Assembly in May 1974. The program's longterm objectives include: to reduce morbidity and mortality from diphtheria, whooping cough, tetanus, measles, tuberculosis, and poliomyelitis by providing immunization services directed against those disease for every child in the world by 1990; to promote countries' self-reliance in the delivery of immunization services within the context of comprehensive health services; and to promote regional self-reliance in matters of vaccine production and quality control. The EPI, which requires a longterm commitment to continued immunization activities, is an essential element of PAHO/WHO's strategy to achieve health for all by the year 2000. Immunization coverage has been included among the indicators which will be used to monitor the success of that strategy at regional and global levels. As of April 1985, available country reports showed that immunization coverage in the Americas had improved considerably since the EPI was launched in 1977. In 1978, for example, only a very small proportion of the children under 1 year of age (less than 10%) outside the US and Canada lived in countr ies where 50% immunization coverage with the EPI vaccines had been attained for this age group. By 1984, over 55% of these children were living in countries where at least 50% infant coverage with DPT and measles vaccines had been attained, and over 80% were living in countries where at least 50% infant coverage with polio vaccine had been attained. Immunization coverage generally improved between 1980-84, especially in the 12 smaller countries of the subregion with populations of less than 130,000. In the period since EPI training activities were initiated in early 1979 through the end of 1984, it is estimated that at least 15,000 health workers attended EPI workshops
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Human rights conflicts experienced by nurses migrating between developed countries.
Palese, Alvisa; Dobrowolska, Beata; Squin, Anna; Lupieri, Giulia; Bulfone, Giampiera; Vecchiato, Sara
2017-11-01
Some developed countries have recently changed their role in the context of international recruitment, becoming donors due to socio-economical and political factors such as recessions. This is also the case in Italy, where there has been a flow of immigrant nurses out of the country that has been documented over the past several years. In a short time, it has become a donor country to other developed European countries, such as the United Kingdom. To advance knowledge in the context of human rights conflicts and ethical implications of the decision-making process of nurses who migrate between developed countries, such as from Italy to the United Kingdom, during times of recession. A case study based on the descriptive phenomenological approach was undertaken in 2014. Participants and research context: A total of 26 Italian newly graduated nurses finding a job in the United Kingdom were interviewed via Skype and telephone. Ethical considerations: The Internal Review Board of the University approved the project. In accordance with the descriptive phenomenological approach undertaken, three main themes emerged: (1) escaping from the feeling of being refused/rejected in order to be desired, (2) perceiving themselves respected, as a person and as a nurse, in a growth project and (3) returning if the country changes its strategy regarding nurses. Ethical implications in the context of human rights, such as autonomy of the decision, social justice and reciprocal obligation, non-maleficence and double effect, have been discussed. The call for investing in nurses and nurses' care in developed countries facing recession is urgent. Investing in nurses means respecting individuals and citizens who are at risk of developing health problems during the recession.
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Nuclear power programmes in developing countries: Promotion and financing
International Nuclear Information System (INIS)
Bennett, L.L.
1987-01-01
In 1986 the Agency's Director General established a Senior Expert Group on Mechanisms to Assist Developing Countries in the Promotion and Planning of Nuclear Power Programmes. This group, which was comprised of 20 experts with extensive experience in the topics to be studied, coming from 15 Member States plus the World Bank, was asked to: identify and analyse the problems of and constraints on nuclear power introduction/expansion in developing countries, with particular attention being paid to the problems of financing nuclear power projects; study mechanisms for dealing with the identified problems and constraints in order to assist developing countries with the promotion and financing of their nuclear power programmes and to determine the role of the IAEA in this context. This paper summarizes the Senior Expert Group's study
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Industrial Clusters and Corporate Social Responsibility in Developing Countries
DEFF Research Database (Denmark)
Lund-Thomsen, Peter; Lindgreen, Adam; Vanhamme, Joelle
2016-01-01
This article provides a review of what we know, what we do not know, and what we need to know about the relationship between industrial clusters and corporate social responsibility (CSR) in developing countries. In addition to the drivers of and barriers to the adoption of CSR initiatives......, this study highlights key lessons learned from empirical studies of CSR initiatives that aimed to improve environmental management and work conditions and reduce poverty in local industrial districts. Academic work in this area remains embryonic, lacking in empirical evidence about the effects of CSR...... a theoretical model to explain why CSR has not become institutionalized in many developing country clusters, which in turn suggests that the vast majority of industrial clusters in developing countries are likely to engage in socially irresponsible behavior....
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Financing arrangements for nuclear power projects in developing countries
International Nuclear Information System (INIS)
1993-01-01
This reference book reviews the main features and problems or difficulties involved in the financing of nuclear power projects with special reference to developing countries. It provides basic information and advice to developing countries interested in nuclear power projects as part of their power sector planning. The book outlines the general characteristics of financing a nuclear power project and presents innovative approaches for power generation financing. It discusses the special conditions and requirements of nuclear power projects and their financing complexities. The focus is on the practical issues that need to be dealt with in order to successfully finance these power projects, as well as the constraints faced by most developing countries. Possible ways and means of dealing with these constraints are presented. 58 refs, figs and tabs
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Managing nuclear knowledge in developing countries. A view from Pakistan
International Nuclear Information System (INIS)
Ahmad, I.
2002-01-01
Full text: For the developing countries, managing nuclear knowledge requires both acquiring know-how from the developed countries as well as building and conserving their own knowledge resource. The rapid growth of information technology culture has made vast amounts of information and database universally accessible although some bars do indeed apply. The challenge, therefore, lies in having a continuous supply of different tiers of trained and competent professionals who can benefit from what is available and can carry on developing the indigenous capability. This presentation focuses on the issues and problems faced in meeting the above challenge. Steps taken in a developing country like Pakistan to manage nuclear knowledge will be discussed. These measures include developing an interface between the universities and the industry as well as concentrating on meeting the specific infrastructure requirements. The task is, however, becoming increasingly difficult for the developing countries because of the fall out of the lack of proper growth in the nuclear industry at the global level, and the large and long-term financial commitments associated with nuclear energy which leave the entire burden of the nuclear power program development on the public sector. (author)
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Development of Reference Training Courses for the Countries Introducing Nuclear Power
Energy Technology Data Exchange (ETDEWEB)
Lee, Eui-Jin; Han, Kyong-Won; Min, Byung-Joo; Nam, Young-Mi [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)
2008-10-15
Human resources development is an important issue for the countries introducing their first nuclear power plant. Countries, which are considering introducing the nuclear power programs, will have to establish their infrastructure required for such programs. Since Korea has successfully achieved her self-reliance in nuclear power technology over the last 3 decades with a rapid expansion of nuclear power program, most of the countries have been interested in the Korean experience on human resources development and also hoped to share the experiences on nuclear training and education. The purpose of this paper is to present reference training courses developed at KAERI which can be shared with countries that need an infrastructure development for nuclear power.
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Practical guidance material for the development, energy and climate country studies
Energy Technology Data Exchange (ETDEWEB)
Halsnaes, K.; Garg, A.; Olhoff, A.; Denton, F.
2006-10-15
The document is developed as part of the Development, Energy and Climate project in order to facilitate methodological consistency and the use of common assumptions in national case studies in Bangladesh, Brazil, China, India, Senegal and South Africa that are conducted as part of the project. In addition to this document the project and country studies are also based on in depth thematic work in three areas namely; 1) Development pathways and climate change; 2) Assessment of Policy Instruments in the Context of Current Market Structure, Institutional Capacities and Risks in Developing Countries; 3) Climate change impacts, vulnerability, and adaptation in the energy sector with a special emphasis given to linkages between adaptation and mitigation policies. The Development, Energy, and Climate project will identify promising energy policy options in the participating countries that are consistent with their national sustainable development objectives. The project teams from Bangladesh, Brazil, China, India, South Africa and Senegal will examine how energy sector policies can be evaluated using specific sustainable development indicators and existing analytical approaches and tools relevant to the countries. The country studies will address energy sector issues, adaptation policies, and alternative scenarios for technology penetration processes. The policy options and the sustainable development impacts of implementing these will be discussed in national stakeholder dialogues with broad participation of government, private sector and NGOs. Cross-country interactions about conceptual and common methodological issues will be covered in three thematic papers. The project will produce a synthesis of the country case studies as an input to various international processes in order to build support for approaches that integrate sustainable development, energy and climate policies. (au)
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SMEs and CSR in Developing Countries
DEFF Research Database (Denmark)
Jamali, Dima; Lund-Thomsen, Peter; Jeppesen, Søren
2017-01-01
This article is the guest editors’ introduction to the special issue in Business & Society on “SMEs and CSR in Developing Countries.” The special issue includes four original research articles by Hamann, Smith, Tashman, and Marshall; Allet; Egels-Zandén; and Puppim de Oliveira and Jabbour...
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Future energy options for developing countries
Energy Technology Data Exchange (ETDEWEB)
Zaric, Z P
1982-05-01
An educated guess is made of the energy demand in developing countries well into the next century in order to estimate the possible role of new and renewable sources in meeting this demand. The world is roughly divided into industrialized (IND) and developing (LDC) countries. A plot of energy demand in both parts shows a possible structure of mixed energy to meet LDC demand, but there is a gap between demand and supply from conventional sources in LDCs that has to be met by new and renewable sources. When the demand for specific energy forms is projected, as much as two thirds of the final energy needed from new sources should be based on centralized-electricity and liquid-fuels technologies. Solar and geothermal energy must compete with nuclear and thermonuclear breeders, while solar prospects for chemical fuel supply in LDCs lacking adequate coal reserves seems promising. There is a large gap in research and development (R and D) spending on new energy between the two parts, which means that LDCs will have inappropriate technology at a high price. An increase in R and D spending on a regional basis should target funds to appropriate options. 6 references, 7 figures.
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Health, globalization and developing countries.
Cilingiroglu, Nesrin
2005-02-01
In health care today, scientific and technological frontiers are expanding at unprecedented rates, even as economic and financial pressures shrink profit margins, intensify competition, and constrain the funds available for investment. Therefore, the world today has more economic, and social opportunities for people than 10 or 100 years since globalization has created a new ground somewhat characterized by rapid economic transformation, deregulation of national markets by new trade regimes, amazing transport, electronic communication possibilities and high turnover of foreign investment and capital flow as well as skilled labor. These trends can easily mask great inequalities in developing countries such as importation and spreading of infectious and non-communicable diseases; miniaturization of movement of medical technology; health sector trades management driven by economics without consideration to the social and health aspects and its effects, increasing health inequalities and their economic and social burden creation; multinational companies' cheap labor employment promotion in widening income differentials; and others. As a matter of fact, all these factors are major determinants of ill health. Health authorities of developing countries have to strengthen their regulatory framework in order to ensure that national health systems derive maximum benefit in terms of equity, quality and efficiency, while reducing potential social cost to a minimum generated risky side of globalization.
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Directory of Open Access Journals (Sweden)
H. Biabi
2016-03-01
Full Text Available Introduction: The role of economic factors in pollution and environmental degradation is one of the major Issues in economic and environmental studies that many researchers have addressed in their studies. One of the issues in the field of environment to which less attention has been paid is the effect of economic factors such as the openness of the economy on water resource pollution. In this paper we investigate the relation between water pollution and economic factors such as economic size, capital to labor ratio and economic openness in two groups of developed and developing countries with paned data method. In fact we investigate the two hypothesis of Environmental Kuznets curve and pollution havens in two groups of countries. To prevent the pollution of groundwater resources in the process of economic growth, policies must be coordinated by responsible organizations. Changing crop patterns and moving toward the production of organic products to reduce the use of polluting substances in the production of agricultural products is one of these solutions. Materials and Methods: In the present study, using panel data methods, the correlation between some independent economic factors such as per capita GDP, Squared per capita GDP that both indicate Scale effect and capital to labor index with Squared capital to labor index both indicating comparative advantage effect and openness of trade and some composite indices on dependent variables, groundwater pollution, in the two groups of countries both developed and developing countries has been investigated. For this purpose, using the biological oxygen demand index (BOD as an indicator of pollution of groundwater resources and sum of exports and imports divided by GDP as an indicator of economic openness and GDP per capita as an indicator of the economy in the period of 1995 to 2006, the Environmental Kuznets curve and pollution havens hypothesis have been tested. Results Discussion: The issue of
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Dondeynaz, C.; Carmona Moreno, C.; Céspedes Lorente, J. J.
2012-10-01
The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS), being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation). These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC) of the European Commission (EC) has developed a new database (WatSan4Dev database) containing 42 indicators (called variables in this paper) from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality, and finally, the analysis to verify the database coherence is presented. Based on 25 relevant variables, the relationships between variables are described and organised into five factors (HDP - Human Development against Poverty, AP - Human Activity Pressure on water resources, WR - Water Resources, ODA - Official Development Aid, CEC - Country Environmental Concern). Linear regression methods are used to identify key variables having influence on water supply and sanitation. First analysis indicates that the informal urbanisation development is an important factor negatively influencing the percentage of the population having access to WSS. Health, and in particular children's health, benefits from the improvement of WSS. Irrigation is also enhancing Water Supply service thanks to multi-purpose infrastructure. Five country profiles are also created to deeper understand and synthetize the amount of information gathered. This new
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Directory of Open Access Journals (Sweden)
C. Dondeynaz
2012-10-01
Full Text Available The "Integrated Water Resources Management" principle was formally laid down at the International Conference on Water and Sustainable development in Dublin 1992. One of the main results of this conference is that improving Water and Sanitation Services (WSS, being a complex and interdisciplinary issue, passes through collaboration and coordination of different sectors (environment, health, economic activities, governance, and international cooperation. These sectors influence or are influenced by the access to WSS. The understanding of these interrelations appears as crucial for decision makers in the water sector. In this framework, the Joint Research Centre (JRC of the European Commission (EC has developed a new database (WatSan4Dev database containing 42 indicators (called variables in this paper from environmental, socio-economic, governance and financial aid flows data in developing countries. This paper describes the development of the WatSan4Dev dataset, the statistical processes needed to improve the data quality, and finally, the analysis to verify the database coherence is presented. Based on 25 relevant variables, the relationships between variables are described and organised into five factors (HDP – Human Development against Poverty, AP – Human Activity Pressure on water resources, WR – Water Resources, ODA – Official Development Aid, CEC – Country Environmental Concern. Linear regression methods are used to identify key variables having influence on water supply and sanitation. First analysis indicates that the informal urbanisation development is an important factor negatively influencing the percentage of the population having access to WSS. Health, and in particular children's health, benefits from the improvement of WSS. Irrigation is also enhancing Water Supply service thanks to multi-purpose infrastructure. Five country profiles are also created to deeper understand and synthetize the amount of information gathered
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Internationalization of science in developing countries
International Nuclear Information System (INIS)
Salam, A.
1980-03-01
The history of science has gone through cycles among nations. In the period of antiquity the centres of science were in the East; in the middle ages scholars from the underdeveloped West travelled to the centres of study and research of the rich countries in the East to learn from the teachers there. In our century the cycle has turned and it is the East that turns to the West for science. Opportunities for scientists from developing countries are diminishing, however, and it is important that centres like the International Centre for Theoretical Physics in Trieste, supported by the IAEA, UNESCO and the Government of Italy, be provided with continuing and strong support
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Perceived Requirements of MIS Curriculum Implementation in Bilingual Developing Countries
Kabeil, Magdy M.
2005-01-01
This paper addresses additional requirements associated with implementing a standard curriculum of Management Information Systems (MIS) in bilingual developing countries where both students and workplace users speak English as a second language. In such countries, MIS graduates are required to develop bilingual computer applications and to…
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Adolescent childbearing in developing countries: a global review.
Singh, S
1998-06-01
This article discusses the current levels and recent trends in the rate of adolescent childbearing, the timing of the first birth, and births to unmarried women for 43 developing countries. Differences in rates of adolescent childbearing by residence and level of education are also examined. The analysis is based on nationally representative fertility surveys. Substantial declines in adolescent fertility have occurred in North Africa and Asia, but levels are still high in some countries. Declines are beginning to occur in sub-Saharan Africa, but current levels are still high in most countries of this region, and the proportion of births to unmarried adolescents is increasing in some countries. In Latin America, where the level of teenage childbearing is moderate, declines are less prevalent and some small increases have occurred. Higher education is associated with lower rates of adolescent childbearing, but other socioeconomic changes cancel or reduce this effect in several countries.
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Capital Flight and Transfer from Resource-Rich Developing Countries
Demachi, Kazue
2013-01-01
This paper analyzes the influence of international resource price movements on capital outflows from resource-rich developing countries (RRDCs) by distinguishing capital flight and capital transfers. The volume of capital flight and transfers are calculated and their determinants are analyzed using macro-panel data constituting 21 resource-rich developing countries from 1990 to 2011. Through the regression analysis, the linkage between capital flight and resource revenue as well as that betwe...
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Nuclear power for developing countries. Key issue paper no. 1
International Nuclear Information System (INIS)
Rogner, H.-H.; Khan, A.M.
2000-01-01
Is there a rationale for developing countries to adopt nuclear power? This paper explores this rationale and the suitability of nuclear power for developing countries by surveying the prerequisites for and implications of developing a nuclear power program: infrastructure availability, economics and finance, environment, the needs for technology transfer, the regulatory and institutional frameworks required and the awareness of public concerns. (author)
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Considerations in promoting markets for sustainable energy technologies in developing countries
International Nuclear Information System (INIS)
Radka, Mark; Kamel, Sami
2003-01-01
The growth in demand for energy in both developed and developing countries is expected to continue an upward trend for many years, with a large portion of the increase projected to occur in developing countries. As these countries undertake various economic development initiatives and programmes it is important from a global environmental perspective that they increase the proportion of efficient, low carbon emitting energy in the energy mix. This paper identifies a number of ways of improving markets that foster increased adoption of clean energy technologies in developing countries. The paper concludes that a holistic approach is needed if new technology promotion efforts are to succeed. Ensuring the appropriateness of the technology, and hence its sustainability, requires proper attention to social, economic and political criteria as well as the fundamental technical characteristics. (au)
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Considerations in promoting markets for sustainable energy technologies in developing countries
Energy Technology Data Exchange (ETDEWEB)
Radka, Mark [United Nations Environment Programme, Div. of Technology, Industry and Economics (France); Kamel, Sami [Risoe National Lab., UNEP Risoe Centre for Energy, Climate Change and Sustainable Development, Roskilde (Denmark)
2003-09-01
The growth in demand for energy in both developed and developing countries is expected to continue an upward trend for many years, with a large portion of the increase projected to occur in developing countries. As these countries undertake various economic development initiatives and programmes it is important from a global environmental perspective that they increase the proportion of efficient, low carbon emitting energy in the energy mix. This paper identifies a number of ways of improving markets that foster increased adoption of clean energy technologies in developing countries. The paper concludes that a holistic approach is needed if new technology promotion efforts are to succeed. Ensuring the appropriateness of the technology, and hence its sustainability, requires proper attention to social, economic and political criteria as well as the fundamental technical characteristics. (au)
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The challenge of electronic waste (e-waste) management in developing countries.
Osibanjo, O; Nnorom, I C
2007-12-01
Information and telecommunications technology (ICT) and computer Internet networking has penetrated nearly every aspect of modern life, and is positively affecting human life even in the most remote areas of the developing countries. The rapid growth in ICT has led to an improvement in the capacity of computers but simultaneously to a decrease in the products lifetime as a result of which increasingly large quantities of waste electrical and electronic equipment (e-waste) are generated annually. ICT development in most developing countries, particularly in Africa, depends more on secondhand or refurbished EEEs most of which are imported without confirmatory testing for functionality. As a result large quantities of e-waste are presently being managed in these countries. The challenges facing the developing countries in e-waste management include: an absence of infrastructure for appropriate waste management, an absence of legislation dealing specifically with e-waste, an absence of any framework for end-of-life (EoL) product take-back or implementation of extended producer responsibility (EPR). This study examines these issues as they relate to practices in developing countries with emphasis on the prevailing situation in Nigeria. Effective management of e-waste in the developing countries demands the implementation of EPR, the establishment of product reuse through remanufacturing and the introduction of efficient recycling facilities. The implementation of a global system for the standardization and certification/labelling of secondhand appliances intended for export to developing countries will be required to control the export of electronic recyclables (e-scarp) in the name of secondhand appliances.
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Mocellin, Simone; Nitti, Donato
2008-05-01
Despite the evidence that immune effectors can play a significant role in controlling tumor growth under natural conditions or in response to therapeutic manipulation, it is clear that malignant cells evade immune surveillance in most cases. Considering that anticancer vaccination has reached a plateau of results and currently no vaccination regimen is indicated as a standard anticancer therapy, the dissection of the molecular events underlying tumor immune escape is the necessary condition to make anticancer vaccines a therapeutic weapon effective enough to be implemented in the routine clinical setting. Recent years have witnessed significant advances in our understanding of the molecular mechanisms underlying tumor immune escape. These mechanistic insights are fostering the development of rationally designed therapeutics aimed at reverting the immunosuppressive circuits that undermine an effective antitumor immune response. In this review, the best characterized mechanisms that allow cancer cells to evade immune surveillance are overviewed and the most debated controversies constellating this complex field are highlighted. In addition, the latest therapeutic strategies devised to overcome tumor immune escape are described, with special regard to those entering clinical phase investigation. Copyright (c) 2007 Wiley-Periodicals, Inc.
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Directory of Open Access Journals (Sweden)
Rupesh Raina
Full Text Available Acute kidney injury (AKI is a common cause of morbidity and mortality worldwide, with a pediatric incidence ranging from 19.3% to 24.1%. Treatment of pediatric AKI is a source of debate in varying geographical regions. Currently CRRT is the treatment for pediatric AKI, but limitations due to cost and accessibility force use of adult equipment and other therapeutic options such as peritoneal dialysis (PD and hemodialysis (HD. It was hypothesized that more cost-effective measures would likely be used in developing countries due to lesser resource availability.A 26-question internet-based survey was distributed to 650 pediatric Nephrologists. There was a response rate of 34.3% (223 responses. The survey was distributed via pedneph and pcrrt email servers, inquiring about demographics, technology, resources, pediatric-specific supplies, and preference in renal replacement therapy (RRT in pediatric AKI. The main method of analysis was to compare responses about treatments between nephrologists in developed countries and nephrologists in developing countries using difference-of-proportions tests.PD was available in all centers surveyed, while HD was available in 85.1% and 54.1% (p = 0.00, CRRT was available in 60% and 33.3% (p = 0.001, and SLED was available in 20% and 25% (p = 0.45 centers of developed and developing world respectively. In developing countries, 68.5% (p = 0.000 of physicians preferred PD to costlier therapies, while in developed countries it was found that physicians favored HD (72%, p = 0.00 or CRRT (24%, p = 0.041 in infants.Lack of availability of resources, trained physicians and funds often preclude standards of care in developing countries, and there is much development needed in terms of meeting higher global standards for treating pediatric AKI patients. PD remains the main modality of choice for treatment of AKI in infants in developing world.
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Ranking of Developing Countries Based on the Economic Freedom Index
Zirak, Masoumeh; Mehrara, Mohsen
2013-01-01
In this paper we’ve ranked developing countries based on the Economic Freedom index. Therefore we are trying to do the analysis how this ranking is done using numerical taxonomic methodology. To do this, by estimating the effects of the determinants of FDI in 123 developing countries from 1997 to 2010, results showed that with regard to the degree of economic freedom or Economic openness, attract foreign direct investment in each country is different. In this study china, Equator, Liberia, Az...
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Evolution of JAK-STAT pathway components: mechanisms and role in immune system development.
Directory of Open Access Journals (Sweden)
Clifford Liongue
Full Text Available BACKGROUND: Lying downstream of a myriad of cytokine receptors, the Janus kinase (JAK-Signal transducer and activator of transcription (STAT pathway is pivotal for the development and function of the immune system, with additional important roles in other biological systems. To gain further insight into immune system evolution, we have performed a comprehensive bioinformatic analysis of the JAK-STAT pathway components, including the key negative regulators of this pathway, the SH2-domain containing tyrosine phosphatase (SHP, Protein inhibitors against Stats (PIAS, and Suppressor of cytokine signaling (SOCS proteins across a diverse range of organisms. RESULTS: Our analysis has demonstrated significant expansion of JAK-STAT pathway components co-incident with the emergence of adaptive immunity, with whole genome duplication being the principal mechanism for generating this additional diversity. In contrast, expansion of upstream cytokine receptors appears to be a pivotal driver for the differential diversification of specific pathway components. CONCLUSION: Diversification of JAK-STAT pathway components during early vertebrate development occurred concurrently with a major expansion of upstream cytokine receptors and two rounds of whole genome duplications. This produced an intricate cell-cell communication system that has made a significant contribution to the evolution of the immune system, particularly the emergence of adaptive immunity.
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Directory of Open Access Journals (Sweden)
Michael J. Nash
2017-12-01
Full Text Available The developing infant gut microbiome affects metabolism, maturation of the gastrointestinal tract, immune system function, and brain development. Initial seeding of the neonatal microbiota occurs through maternal and environmental contact. Maternal diet, antibiotic use, and cesarean section alter the offspring microbiota composition, at least temporarily. Nutrients are thought to regulate initial perinatal microbial colonization, a paradigm known as the “Restaurant” hypothesis. This hypothesis proposes that early nutritional stresses alter both the initial colonizing bacteria and the development of signaling pathways controlled by microbial mediators. These stresses fine-tune the immune system and metabolic homeostasis in early life, potentially setting the stage for long-term metabolic and immune health. Dysbiosis, an imbalance or a maladaptation in the microbiota, can be caused by several factors including dietary alterations and antibiotics. Dysbiosis can alter biological processes in the gut and in tissues and organs throughout the body. Misregulated development and activity of both the innate and adaptive immune systems, driven by early dysbiosis, could have long-lasting pathologic consequences such as increased autoimmunity, increased adiposity, and non-alcoholic fatty liver disease (NAFLD. This review will focus on factors during pregnancy and the neonatal period that impact a neonate’s gut microbiome, as well as the mechanisms and possible links from early infancy that can drive increased risk for diseases including obesity and NAFLD. The complex pathways that connect diet, the microbiota, immune system development, and metabolism, particularly in early life, present exciting new frontiers for biomedical research.
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Vonasek, Bryan J; Bajunirwe, Francis; Jacobson, Laura E; Twesigye, Leonidas; Dahm, James; Grant, Monica J; Sethi, Ajay K; Conway, James H
2016-01-01
Improving childhood vaccination coverage and timeliness is a key health policy objective in many developing countries such as Uganda. Of the many factors known to influence uptake of childhood immunizations in under resourced settings, parents' understanding and perception of childhood immunizations has largely been overlooked. The aims of this study were to survey mothers' knowledge and attitudes towards childhood immunizations and then determine if these variables correlate with the timely vaccination coverage of their children. From September to December 2013, we conducted a cross-sectional survey of 1,000 parous women in rural Sheema district in southwest Uganda. The survey collected socio-demographic data and knowledge and attitudes towards childhood immunizations. For the women with at least one child between the age of one month and five years who also had a vaccination card available for the child (N = 302), the vaccination status of this child was assessed. 88% of these children received age-appropriate, on-time immunizations. 93.5% of the women were able to state that childhood immunizations protect children from diseases. The women not able to point this out were significantly more likely to have an under-vaccinated child (PR 1.354: 95% CI 1.018-1.802). When asked why vaccination rates may be low in their community, the two most common responses were "fearful of side effects" and "ignorance/disinterest/laziness" (44% each). The factors influencing caregivers' demand for childhood immunizations vary widely between, and also within, developing countries. Research that elucidates local knowledge and attitudes, like this study, allows for decisions and policy pertaining to vaccination programs to be more effective at improving child vaccination rates.
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Sanitation planning in developing countries
Kerstens, S.M.
2016-01-01
Sanitation planning in developing countries: Added value of resource recovery Worldwide 2.5 billion people lack access to sanitation. This impacts human live, the environment and represents a loss of valuable resources that can be regained from wastewater. This study shows that resource recovery can be a potential driver to accelerate sanitation. A new sanitation decision framework for policy makers was created and tested in Indonesia. The variety of advantages and disadvantages of sanitatio...
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Directory of Open Access Journals (Sweden)
Mellova Amir Masrizal
2003-08-01
Full Text Available Infection, occurring with malnutrition, is a major cause of morbidity in all age groups and is responsible for two-thirds of all death under 5 yr of age in developing countries. Many cells of the immune system are known to depend for their function on metabolic pathways that employ various nutrients as critical factors. The most consistent changes in immune competence in PEM are in cell-mediated immunity, the bactericidal function of neutrophils, the complement system, the secretory immunoglobin A, and antibody response.
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Sustainable development and climate change: Lessons from country studies
DEFF Research Database (Denmark)
Halsnæs, Kirsten; Shukla, P.; Garg, A.
2008-01-01
Sustainable development has been suggested as a framework for integrating development and climate change policies in developing countries. Mainstreaming climate change into sustainable development policies would allow these countries to achieve their development goals while addressing climate...... change. A number of research programmes have investigated how potential synergies could be achieved at national level and what kind of trade-offs between the various aspects of sustainable development have to be faced. An overview of these studies is provided, focusing on national case studies....... The energy and transportation sectors are covered in many studies, but some attention is also given to the infrastructure sector and water supply. Most existing development policies will not lead to a sustainable development pattern, since they insufficiently address climate change. However, good...
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Challenges And Opportunities For Coal Gasification In Developing Countries
Energy Technology Data Exchange (ETDEWEB)
NONE
2013-10-01
Coal gasification for chemicals, gaseous and liquid fuels production can fulfil an important strategic need in those developing countries where coal is the primary fuel source and oil and gas energy security is an issue. At the same time, the establishment of major projects in such countries can be problematical for a number of technical and economic reasons, although it is encouraging that some projects appear to be moving forward. There are two developing countries where coal conversion projects to produce chemicals, gaseous and liquid fuels have been taken forward strongly. The first is South Africa, which established the world's only commercial-scale coal-to-liquids and coal-to-chemicals facilities at Secunda and Sasolburg respectively. The other is China, where there is a major gasification-based coal conversion development and deployment programme that is set to become a significant, large-scale commercial element in the nation's energy development plans. This will provide further major opportunities for the deployment of large-scale coal gasification technologies, various syngas conversion units and catalysts for the subsequent production of the required products. The role of China is likely to be critical in the dissemination of such technologies to other developing countries as it can not only provide the technical expertise but also financially underpin such projects, including the associated infrastructure needs.
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Developing Enterprise Architecture Skills: A Developing Country Perspective
Shaanika , Irja; Iyamu , Tiko
2014-01-01
Part 1: Key Competencies for Educating ICT Professionals; International audience; Through different approaches, organisations strive to evolve their competitiveness, as well as their addressing their operational and strategic needs. Some organisations employ Enterprise Architecture (EA), to bridge the gap between the business and IT, and to providing strategic goals. However, there exists scarcity of EA Skills in many developing countries. This could be attributed to the uniqueness of the dis...
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Tracking financial flows for immunization in Honduras.
Valdés, Werner; Janusz, Cara Bess; Molina Aguilera, Ida Berenice; Mendoza, Lourdes; Díaz, Iris Yolanda; Resch, Stephen
2015-05-07
In Honduras, until 2008, vaccine and injection supplies were financed with domestic resources. With the introduction of rotavirus vaccine in 2009 and pneumococcal conjugate in 2011, the country's Expanded Program on Immunization required an influx of resources to support not only vaccine procurement but also investments in cold chain infrastructure and programmatic strategies. This paper examines the origin, allocation, and use of resources for immunization in 2011 in Honduras, with the aim of identifying gaps in financing. An adaptation of the System of Health Accounts (2011) codes was used to specifically track resources for immunization services in Honduras for 2011. All financial flows were entered into an Excel database, and each transfer of resources was coded with a financing source and a financing agent. These coded financing sources were then distributed by provider, health care function (activity), health care provision (line item or resource input), and beneficiary (geographic, population, and antigen). All costs were calculated in 2011 United States dollars. In 2011, financing for routine immunization in Honduras amounted to US$ 49.1 million, which is equal to 3.3% of the total health spending of US$ 1.49 billion and 0.29% of the GDP. Of the total financing, 64% originate from domestic sources. The other 36% is external financing, most importantly Gavi support for introducing new vaccines. This analysis identified potential financing gaps for many immunization-related activities besides procuring vaccines, such as expanding the cold chain, training, social mobilization, information systems, and research. The funding for Honduras' immunization program is a small share of total public spending on health. However, new vaccines recently added to the schedule with financial support from Gavi have increased the financing requirements by more than 30% in comparison to 2008. The Honduran government and its partners are developing sustainability plans to cover a
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Problems of scientific research in developing countries
International Nuclear Information System (INIS)
Vose, P.B.; Cervellini, A.
1983-01-01
The paper gives a general consideration of the problems encountered in the scientific research by the developing countries. Possible optimizations in the long term as well as short term strategies are pointed out
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Episodes of non-employment among immigrants from developing countries in Canada
Directory of Open Access Journals (Sweden)
Said Ahmed Aboubacar
2013-01-01
Full Text Available Using data from the Survey of Labour and Income Dynamics (SLID, we analyze non-employment episodes for immigrants from developing countries, and compare their situation to that of immigrants from developed countries and Canadian-born individuals between 1996 and 2006. The methods used allowed us to draw the following conclusion: significant differences exist between these three groups in labour market mobility, the average duration of a non-employment episode, and the factors that affect the propensity to exit from a non-employment episode. These differences demonstrate a particular disadvantage for immigrants from developing countries. In fact, they tend to spend more time in non-employment episodes compared to their counterparts from developed countries, and compared to Canadian-born individuals.
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Episodes of non-employment among immigrants from developing countries in Canada
Directory of Open Access Journals (Sweden)
Said Ahmed Aboubacar
2013-05-01
Full Text Available Using data from the Survey of Labour and Income Dynamics (SLID, we analyze non-employment episodes for immigrants from developing countries, and compare their situation to that of immigrants from developed countries and Canadian-born individuals between 1996 and 2006. The methods used allowed us to draw the following conclusion: significant differences exist between these three groups in labour market mobility, the average duration of a non-employment episode, and the factors that affect the propensity to exit from a nonemployment episode. These differences demonstrate a particular disadvantage for immigrants from developing countries. In fact, they tend to spend more time in non-employment episodes compared to their counterparts from developed countries, and compared to Canadian-born individuals.
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Energy sector assistance in developing countries: Current trends and policy recommendations
International Nuclear Information System (INIS)
Tharakan, Pradeep J.; Castro, Julio de; Kroeger, Timm
2007-01-01
An estimated 2.5 billion people remain without access to modern energy supplies. This shortfall is expected to grow as the population in developing countries continues to grow rapidly and the existing infrastructure ages. The United Nations' goal of lowering poverty by half by 2015 will not be attained unless the poor in developing countries gain greater access to basic infrastructure and services, including energy services. The key objective of this paper is to analyze trends in overseas development assistance (ODA) to the energy sector in developing countries during the period 1990-2003, relative to realized private sector investments. This analysis then forms the basis for policy recommendations for consideration by decision makers within countries that are major contributors to ODA
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Significance and impact of nuclear research in developing countries
International Nuclear Information System (INIS)
1987-01-01
The main purpose of this conference was to gather representatives of universities, research institutes, governmental agencies and industry, as well as IAEA staff, to report on and to assess the significance and impact of nuclear science and technology in developing countries. Thirty-four papers from 17 countries were presented, which are included in the proceedings, as well as reports of three workshops on ''Basic and applied research'', on ''The IAEA's involvement in the implementation of national nuclear programmes'', and on ''Policy and management issues''. The presentation of these reports clearly reflects the fact that all the nuclear activities involved in the programmes of industrialized countries are in progress in developing countries, i.e. most of the aspects of applications in the field of nuclear power, research reactors, food and agriculture, industry and earth sciences, and life sciences. A separate abstract was prepared for each of these papers
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Development performances of agriculture in the Danube region countries
Directory of Open Access Journals (Sweden)
Gajić Milivoj
2015-01-01
Full Text Available In the recent decades, the Danube Region countries profile their policies towards a more efficient way of exploiting the natural resources of the Danube basin. The Danube can contribute to a better integration of the countries, enhancing economic opportunities through diversification and promotion of rural development. The trend analysis in the agricultural sector of the Danube Region countries refers to the first decade of this century, and it begins with the determination of the agricultural importance in the overall economy. The development performances of agriculture in the Danube Region countries are considered according to the production and export performances of this economic sector, using a comparative approach. The agricultural production growth, level and growth of the partial agricultural productivities - labour and land, as well as the value of exports in relation to engaged labour and agricultural land, are analysed in such a context.
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Microglia and Beyond: Innate Immune Cells As Regulators of Brain Development and Behavioral Function
Directory of Open Access Journals (Sweden)
Kathryn M. Lenz
2018-04-01
Full Text Available Innate immune cells play a well-documented role in the etiology and disease course of many brain-based conditions, including multiple sclerosis, Alzheimer’s disease, traumatic brain and spinal cord injury, and brain cancers. In contrast, it is only recently becoming clear that innate immune cells, primarily brain resident macrophages called microglia, are also key regulators of brain development. This review summarizes the current state of knowledge regarding microglia in brain development, with particular emphasis on how microglia during development are distinct from microglia later in life. We also summarize the effects of early life perturbations on microglia function in the developing brain, the role that biological sex plays in microglia function, and the potential role that microglia may play in developmental brain disorders. Finally, given how new the field of developmental neuroimmunology is, we highlight what has yet to be learned about how innate immune cells shape the development of brain and behavior.
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Lenz, Kathryn M; Nelson, Lars H
2018-01-01
Innate immune cells play a well-documented role in the etiology and disease course of many brain-based conditions, including multiple sclerosis, Alzheimer's disease, traumatic brain and spinal cord injury, and brain cancers. In contrast, it is only recently becoming clear that innate immune cells, primarily brain resident macrophages called microglia, are also key regulators of brain development. This review summarizes the current state of knowledge regarding microglia in brain development, with particular emphasis on how microglia during development are distinct from microglia later in life. We also summarize the effects of early life perturbations on microglia function in the developing brain, the role that biological sex plays in microglia function, and the potential role that microglia may play in developmental brain disorders. Finally, given how new the field of developmental neuroimmunology is, we highlight what has yet to be learned about how innate immune cells shape the development of brain and behavior.
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Capacity building for higher education in developing countries
DEFF Research Database (Denmark)
Enemark, Stig
2006-01-01
"Higher education is the modern world's basic education, but many countries are falling further and further behind". This quote from a recent World Bank publication indicates that the role of the universities as a key driver for societal development is now widely recognized and included...... in the donor policies. However, donor projects are not easy to organize in this area, and the role of the western universities in this area is not easy to identify. The paper presents a case study from Mozambique dealing with a World Bank project in Higher Education. The project was focused on qualitative...... in the donor countries in order to merge the interests of the universities, the Ministry of Science/Education and the national/international donor agencies. It is argued that capacity building for higher education in developing countries should be a generally accepted part of the university strategy portfolio...
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International Nuclear Information System (INIS)
Nguyen, A.T.
2000-01-01
In the first part, a contextual grid is built which aims at presenting the main impacts of development in developing countries. Some development trends, like energy consumption growth, environmental courses, economic growth and demographic development are analyzed. Then, a global modeling analysis of Kuznets' environmental curves and of development prospect is presented. The second part presents different types of policy instruments for environment protection, and the theoretical challenges and experience feedback of their implementation in OECD countries, in particular in the energy sector. It treats also of the energy-environment policy practices and of their environmental impacts on the economy, of the role of institutional factors in the environmental management in the fast developing Asian countries. The environmental management priorities in an integrated approach in these countries are presented and compared with environmental management experiences in the OECD countries. In the third part, the case study of the power industry sector in Vietnam aims at making an inventory of the emissions in a rapidly developing sector with important atmospheric emissions and at making a critical status of the evaluation instruments of environmental policies by comparing approaches based on 'bottom-up' and 'top-down' models. Finally, a model and a set of scenarios allowing to evaluate the economical and environmental consequences of the setting up of a sectoral policy in a transition economy context are presented. (J.S.)
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Financing of nuclear power projects in developing countries
International Nuclear Information System (INIS)
1991-06-01
This document is a summary of the ''Topical Seminar on Financing of Nuclear Power Projects in Developing Countries, held in Jakarta between 4-7 September, 1990. The seminar presentations were divided into the following sessions: Keynote session (3 papers), Perspective of Nuclear and Fossil-fired Generation Costs (9 papers), Assessment of Problems and Constraints for the Financing of Large Power Projects, with particular Attention to Nuclear Power Projects (9 papers), Mechanisms for Financing Nuclear Power Projects in Developing Countries (11 papers). A separate abstract was prepared for each of these papers. Refs, figs, tabs and charts
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The impact of irradiated food on developing countries
International Nuclear Information System (INIS)
Pothisiri, P.; Kiatsurayanont, P.
1991-01-01
The demand for food and agricultural products in the developing countries is expected to increase - a reduction in food losses would be beneficial. Most fruits and vegetables are perishable and have a limited marketable life. There are a number of technologies which could be used to extend the marketable life of these commodities e.g chemical preservatives, drying, freezing, canning and irradiation. Much work has been done in the use of irradiation in the preservation of food and also in the control of foodborne diseases which is of particular importance in the developing countries of Asia and the Pacific Region. (author)
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ICT diffusion in developing countries towards a new concept of technological takeoff
Lechman, Ewa
2015-01-01
This book provides an extensive overview of the diffusion of Information and Communication Technologies (ICTs) in developing countries between 2000 and 2012. It covers issues such as country-specific ICT diffusion patterns, technological substitution and technological convergence. By identifying social, economic and institutional prerequisites and analyzing critical country-specific conditions, the author develops a new approach to explaining the emergence of their technological takeoff. Readers will discover how developing countries are now adopting ICTs, rapidly catching up with the developed world in terms of ICT access and use.
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The role of population on economic growth and development: evidence from developing countries
Atanda, Akinwande A.; Aminu, Salaudeen B.; Alimi, Olorunfemi Y.
2012-01-01
The precise relationship between population growth and per capita income has been inconclusive in the literature and the nexus has been found not clearly explain the determinants of rapid population growth in developing countries that lacks fertility control and management framework. This forms the rationale for this study to access the trend of factors that influence rapid population growth in developing countries between 1980 and 2010. This paper examined the comparative trend review of pop...
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Education and Rural Development in the 31 Least Developed Countries. Reports Studies...S.97.
Zuberi, Habib
The report contains information based on the country presentation papers submitted by the 31 countries for the 1981 United Nations Conference on the Least Developed Countries (LDCs). It is intended as a background document for the Unesco meeting of experts from the LDCs on "needs and priorities in regard to education" to be held at…
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Classification of EU Countries in Terms of the Level of Sustainable Development
Directory of Open Access Journals (Sweden)
Stec Małgorzata
2017-01-01
Full Text Available This article has classified the EU countries in terms of the level of sustainable development. The study was based on main sustainability indicators developed by Eurostat. In empirical research, one of the methods used was Cluster Analysis - Ward's method. Grouping methods make it possible to distinguish countries with a similar level of sustainability which is particularly useful for monitoring the progress of individual EU countries in implementation of the Sustainable Development Strategy. For specific groups of countries, appropriate control instruments and strategies can be proposed. The research period is 2016. As a result of the research, 6 clusters of countries were obtained. For specific groups of countries, their characteristics were defined.
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Business symbiosis between developing and industrialised countries
International Nuclear Information System (INIS)
Alfsen, Knut H.; Sygna, Linda
1999-01-01
The article discusses problems of soil conservation and use. Research into the possibilities of improving soil quality by carbon storage is surveyed. An integration of soil carbon storage into the green development mechanisms in the Kyoto protocol may prove to be environmentally beneficial and economically profitable to both the developing and the industrialised countries
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ACTS for distance education in developing countries
Kalu, A.; Ventre, G.
1995-08-01
The need for electrical energy supply in the rural communities of developing countries has been well documented. Equally well known is the potential for photovoltaic in cost effectively meeting this need. A major impediment to fulfilling the need is the lack of indigenous personnel with a knowledgeof photovoltaic systems, and the associated infrastructure required to implement project. Various delivery schemes for providing the needed training to developing countries personnel have been investigated. Various train methods and programs that have been employed to remedy the problem have had significant drawbacks in terms of cost, consistency, impact, reach, and sustainability. The hypothesis to be tested in this project posits that satellite-based distance education using ACTS technologies can overcome these impediments. The purpose of the project is to investigate the applicability of the ACTS satellite in providing distance education in photovoltaic systems to developing countries and rural communities. An evaluation of the cost effectiveness of using ACTS unique technologies to overcome identified problems shall be done. The limitations of ACTS in surmounting distance education problems in developing countries shall be investigated. This project will, furthermore, provide training to Savannah State College faculty in photovoltaic (PV) systems and in distance education configurations and models. It will also produce training materials adequate for use in PV training programs via distance education. Savannah State College will, as a consequence become well equipped to play a leading role in the training of minority populations in photovoltaic systems and other renewables through its Center for Advanced Water Technology and Energy Systems. This communication provides the project outline including the specific issues that will be investigated during the project. Also presented i the project design which covers the participations of the various components of a network