WorldWideScience

Sample records for develop adaptive protection

  1. Adaptive protection algorithm and system

    Science.gov (United States)

    Hedrick, Paul [Pittsburgh, PA; Toms, Helen L [Irwin, PA; Miller, Roger M [Mars, PA

    2009-04-28

    An adaptive protection algorithm and system for protecting electrical distribution systems traces the flow of power through a distribution system, assigns a value (or rank) to each circuit breaker in the system and then determines the appropriate trip set points based on the assigned rank.

  2. Adaptive Distance Protection for Microgrids

    DEFF Research Database (Denmark)

    Lin, Hengwei; Guerrero, Josep M.; Quintero, Juan Carlos Vasquez

    2015-01-01

    Due to the increasing penetration of distributed generation resources, more and more microgrids can be found in distribution systems. This paper proposes a phasor measurement unit based distance protection strategy for microgrids in distribution system. At the same time, transfer tripping scheme...... is adopted to accelerate the tripping speed of the relays on the weak lines. The protection methodology is tested on a mid-voltage microgrid network in Aalborg, Denmark. The results show that the adaptive distance protection methodology has good selectivity and sensitivity. What is more, this system also has...

  3. The human lung cell line A549 does not develop adaptive protection against the DNA-damaging action of formaldehyde.

    Science.gov (United States)

    Speit, Günter; Neuss, Simone; Schmid, Oliver

    2010-03-01

    The alkaline comet assay was used to further characterize the induction of DNA-protein crosslinks (DPX) by formaldehyde (FA) and their removal in the human lung cell line A549. DPX were indirectly measured as the reduction of gamma ray-induced DNA migration. Repeated treatments of A549 cells with low FA concentrations (up to 100 microM) did not lead to significant differences in the induction of DPX in comparison with a single treatment. Pretreatment with higher FA-concentrations (200 microM and above) enhanced the crosslinking effect. There was no indication for an adaptive protection against the induction of DPX by FA. These findings are in agreement with RT-PCR measurements of the expression of genes that encode the main enzymes involved in FA detoxification. A549 cells exposed to FA (50-300 microM) for 1, 4, or 24 hr did not reveal altered expression of the GSH-dependent formaldehyde dehydrogenase (FDH, which is identical to alcohol dehydrogenase 3; ADH3), the cytosolic aldehyde dehydrogenase 1 (ALDH1A1) and the mitochondrial ALDH2. Pretreatment of A549 cells with a low FA concentration (50 microM) also did not enhance the removal of DPX induced by higher FA concentrations. Taken together, these results suggest that A549 cells do not develop adaptive protection against the genotoxic action of FA. Neither metabolic inactivation of FA nor the repair of FA-induced DPX seems to be enhanced in cells pretreated with FA.

  4. The low prevalence of female smoking in the developing world: gender inequality or maternal adaptations for fetal protection?

    Science.gov (United States)

    Hagen, Edward H.; Garfield, Melissa J.; Sullivan, Roger J.

    2016-01-01

    Background: Female smoking prevalence is dramatically lower in developing countries (3.1%) than developed countries (17.2%), whereas male smoking is similar (32% vs 30.1%). Low female smoking has been linked to high gender inequality. Alternatively, to protect their offspring from teratogenic substances, pregnant and lactating women appear to have evolved aversions to toxic plant substances like nicotine, which are reinforced by cultural proscriptions. Higher total fertility rates (TFRs) in developing countries could therefore explain their lower prevalence of female smoking. Objective: To compare the associations of TFR and gender inequality with national prevalence rates of female and male smoking. Methods: Data from a previous study of smoking prevalence vs gender inequality in 74 countries were reanalysed with a regression model that also included TFR. We replicated this analysis with three additional measures of gender equality and 2012 smoking data from 173 countries. Results: A 1 SD increase in TFR predicted a decrease in female smoking prevalence by factors of 0.58–0.77, adjusting for covariates. TFR had a smaller and unexpected negative association with male smoking prevalence. Increased gender equality was associated with increased female smoking prevalence, and, unexpectedly, with decreased male smoking prevalence. TFR was also associated with an increase in smoking prevalence among postmenopausal women. Conclusions: High TFR and gender inequality both predict reduced prevalence of female smoking across nations. In countries with high TFR, adaptations and cultural norms that protect fetuses from plant toxins might suppress smoking among frequently pregnant and lactating women. PMID:27193200

  5. Obstacles to adaptation decisions in the developing world: A case study of coastal protection measures and sea-level rise in Kiribati

    Science.gov (United States)

    Donner, S. D.; Webber, S.

    2014-12-01

    International aid is increasingly focused on adaptation to climate change. At recent meetings of the parties to the United Nations Framework Convention on Climate Change, the developed world agreed to rapidly increase international assistance to help the developing world respond to the impacts of climate change. Here, we examine the decision-making challenges facing internationally supported climate change adaptation projects given the large uncertainty in future climate predictions, using the example of efforts to implement coastal protection measures (e.g. sea walls, mangrove planting) in Kiribati. The central equatorial Pacific country is home to the Kiribati Adaptation Project, the first national-level climate change adaptation project supported by the World Bank. Drawing on interview and document research conducted over an 8-year period, we trace the forces influencing decisions about coastal protection measures, starting from the variability and uncertainty in climate change projections, through the trade-offs between different measures, to the social, political, and economic context in which decisions are finally made. We then discuss how sub-optimal adaptation measures may be implemented despite years of planning, consultation, and technical studies. This qualitative analysis of the real-world process of climate change adaptation reveals that embracing a culturally appropriate and short-term (~20 years) planning horizon, while not ignoring the longer-term future, may reduce the influence of scientific uncertainty on decisions and provide opportunities to learn from mistakes, reassess the science, and adjust suboptimal investments.

  6. Adaptive load shedding and regional protection

    Energy Technology Data Exchange (ETDEWEB)

    Ford, J.J.; Ledwich, G. [School of Engineering Systems, Queensland University of Technology, Brisbane, Qld 4001 (Australia); Bevrani, H. [Department of Electrical and Computer Engineering, University of Kurdistan Sanandaj, Kurdistan (Iran)

    2009-11-15

    The requirement for improved efficiency whilst maintaining system security necessitates the development of improved system analysis approaches and the development of advanced emergency control technologies. Load shedding is a type of emergency control that is designed to ensure system stability by curtailing system load to match generation supply. This paper presents a new adaptive load shedding scheme that provides emergency protection against excess frequency decline, whilst minimizing the risk of line overloading. The proposed load shedding scheme uses the local frequency rate information to adapt the load shedding behaviour to suit the size and location of the experienced disturbance. The proposed scheme is tested in simulation on a 3-region, 10-generator sample system and shows good performance. (author)

  7. Overcurrent adaptive protection; Proteccion adaptiva de sobrecorriente

    Energy Technology Data Exchange (ETDEWEB)

    Conde Enriquez, Arturo

    1996-01-01

    The operating conditions of the electrical power systems demand protection schemes that suitably fulfill the reliability, operation velocity, selectivity and sensitivity requirements. The variable character of the operation regime makes it difficult to give an answer to these requirements with conventional protections, whose adjustment parameters are fixed. This has impelled the development of adaptive protections, able to modify its adjustment parameters or their operation characteristics in response to the power system changes. In this sense, in the last years, works have been reported, which leaves in evidence the increasing importance that this new protection alternative is acquiring. In the present thesis one departs from an analysis of the protection adaptive control and supervisory functions, that have been settled out for transmission, sub-transmission and distribution networks. The limitations of the conventional overcurrent protections are studied and a new type of adaptive overcurrent protection is proposed. The characteristics of the overcurrent protection from the stand point of their operation principle and of the calculation methodology for the parameters adjustment are studied; the main functional limitations of this type of protection are set down, and its possible solution by means of the incorporation of adaptive logics to the overecurrent relay. In the work it is proposed to equip the overcurrent relay with the capacity of varying its starting current and its operation time curve in accordance with the load current level, that indirectly represents the generation state; with it, the relay has greater sensitivity and shorter operation time, most of all at minimum generation conditions. The adaptive and conventional relays are analyzed and compared from the stand point of their scope and its operation time and the advantages and disadvantages of the adaptive relay on the conventional relay are presented. A new methodology for the calculation of

  8. Adaptive urban development

    NARCIS (Netherlands)

    Dr. ing Rutger de Graaf

    2012-01-01

    Adaptive urban development is the design, construction and continuing evolution of urban areas to anticipate and react to changes in the environment and society. These changes include both processes within the city itself and external developments. It is expected that until 2100 a total of 5 billion

  9. The ongoing development of a pragmatic and adaptive fire management policy in a large African savanna protected area.

    Science.gov (United States)

    van Wilgen, Brian W; Govender, Navashni; Smit, Izak P J; MacFadyen, Sandra

    2014-01-01

    This paper describes recent changes to the fire management policy of the 1.9 million ha Kruger National Park in South Africa. It provides a real-life example of adaptive learning in an environment where understanding is incomplete, but where management nonetheless has to proceed. The previous policy called for the application of fire to meet burnt area targets that were set for administrative subdivisions, and that were assessed at the scale of the entire park. This was problematic because the park is large and heterogeneous, and because sound ecological motivations that could link burning prescriptions to ecological objectives were missing. The new policy divides the park into five fire management zones on the basis of differences in mean annual rainfall, historic fire return periods, and geology. In addition, it proposes fire management actions designed to achieve specified ecological objectives in each zone, and includes fire-regime related thresholds and associated ecological outcomes against which to assess the effectiveness of management. The new policy is an improvement over previous iterations, but several challenges remain. Most important among these would be to continually improve the understanding of the effects of fire, and to develop frameworks for assessing the impacts of fire together with other ecosystem drivers that interact strongly with fire to influence the attainment of ecological objectives.

  10. Adaptive immune resistance: How cancer protects from immune attack

    Science.gov (United States)

    Ribas, Antoni

    2015-01-01

    Adaptive immune resistance is a process where the cancer changes its phenotype in response to a cytotoxic or pro-inflammatory immune response, thereby evading it. This adaptive process is triggered by the specific recognition of cancer cells by T cells, which leads to the production of immune-activating cytokines. Cancers then hijack mechanisms developed to limit inflammatory and immune responses and protect themselves from the T cell attack. Inhibiting adaptive immune resistance is the mechanistic basis of responses to PD-1 or PD-L1 blocking antibodies, and may be of relevance for the development of other cancer immunotherapy strategies. PMID:26272491

  11. Advanced Adaptive Optics Technology Development

    Energy Technology Data Exchange (ETDEWEB)

    Olivier, S

    2001-09-18

    The NSF Center for Adaptive Optics (CfAO) is supporting research on advanced adaptive optics technologies. CfAO research activities include development and characterization of micro-electro-mechanical systems (MEMS) deformable mirror (DM) technology, as well as development and characterization of high-resolution adaptive optics systems using liquid crystal (LC) spatial light modulator (SLM) technology. This paper presents an overview of the CfAO advanced adaptive optics technology development activities including current status and future plans.

  12. Tracking adaptation and measuring development

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Nick; Anderson, Simon; Ayers, Jessica; Burton, Ian; Tellam, Ian

    2011-11-15

    This is the first paper in the new IIED Climate Change Working Paper series. As adaptation to climate change becomes the focus of increasing attention and the target of significant spending, there is a growing need for frameworks and tools that enable organisations to track and assess the outcomes of adaptation interventions. This paper presents a coherent framework for climate change adaptation programming, including potential indicators, or indicator categories/types, for tracking and evaluating the success of adaptation support and adaptation interventions. The paper begins with a discussion of some of the key issues related to the evaluation of adaptation, and outlines some of the main difficulties and constraints with respect to the development of adaptation indicators. Next, an evaluation framework is proposed and indicator categories or 'domains' are identified. Lastly, key conclusions are provided and a theory of change is outlined that shows how development and use of the framework could lead to more effective adaptation investments for climate resilient development.

  13. An adaptive overcurrent protection in smart distribution grid

    DEFF Research Database (Denmark)

    Bhattarai, Bishnu Prasad; Bak-Jensen, Birgitte; Chaudhary, Sanjay Kumar

    2015-01-01

    High penetration of distributed energy resources (DERs) creates various protection challenges, such as protection blinding, false tripping, unsynchronized reclosing, etc. Additionally, adaptation of active network management approaches namely demand response and network reconfiguration also threats...... existing protection practice. In this study, a combination of a local adaptive and communication assisted central protection is proposed, whereby the relay settings are dynamically updated based on online identification of the network topologies and status of DERs. Particularly, the local adaptive...... protection updates relay settings based on DERs status (ON/OFF) employing locally acquired information, whereas the centralized protection updates the relay settings during major changes in grid topologies: network reconfiguration and switching between islanded and gridconnected modes. The effectiveness...

  14. Decentralized Adaptive Overcurrent Protection for Medium Voltage Maritime Power Systems

    DEFF Research Database (Denmark)

    Ciontea, Catalin-Iosif; Bak, Claus Leth; Blaabjerg, Frede;

    2016-01-01

    control unit. The new adaptive protection method is based on communication between the overcurrent relays and the equipment that could affect the protection system, such as circuit breakers and generators. Using PSCAD, the proposed method is implemented in a test medium voltage maritime power system...

  15. Multiagents-based wide area protection with best-effort adaptive strategy

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Yongli; Wang, Dewen [North China Electric Power University, Baoding (China); Song, Shaoqun [Fuzhou Electric Power Industry Bureau, Fujian Province (China)

    2009-02-15

    Abstract - Multi-trips of circuit breakers often occur within a short period in a severe blackout, and the tripping usually relates to relays' mal-operations. In fact, when two ore more electric primary devices are isolated by circuit breakers, the settings of most relays to protect their power system are getting infeasible and uncoordinated. Adaptive settings are needed to prevent them from wrong operation. This paper presents an adaptive protection scheme based on wide area information with best-effort protection strategy, and the outline of multiagents and WAN Based Adaptive Protection System (MAWAPS). In the scheme, the best-effort adaptive strategy is used to guarantee the adaptive settings to operate safely and effectively in most situations. The IP/SDH-based wide area network (WAN) is used to realize real-time wide area information exchange in the proposed protection scheme. Adaptive setting algorithms for the second stage zero-sequence current and phase overcurrent relays are proposed, which can provide larger line coverage than traditional relays. Moreover, multiagent techniques and IEC 61850 are employed to realize the fast communication between different agents, and MMS plays a prominent role in real-time remote communication. A simulating system has been developed according to the above ideas and approaches, and the experimental results show that the proposed adaptive protection scheme is feasible from the view of protective performance including the executing time. (author)

  16. ADAPTABLE DESIGN IN PRODUCT DEVELOPMENT

    Institute of Scientific and Technical Information of China (English)

    WU Qingming; MEI Huafeng

    2006-01-01

    A newly emerging design pattern, named as adaptable design (AD), which aims at developing products that are adaptable from design to post-life cycle, is discussed. AD consists of four main phases: product modeling, design platform, specific design and product redesign. A new process-based design data model (PDDM) is presented which is organized according to the principles of conveniem knowledge extraction, data representation, layout, sharing and reuse. Based on the PDDM, a universal design platform for product family development is established, which has characters of modularity, parameter-driven, variant design, etc. The framework of the platform is also proposed as a conceptual structure and overall logical organization for generating a family of products. AD methodology is successfully applied to develop a family of tunnel boring machine (TBM) for different engineering projects, with the efficiency of our developing team being greatly increased.

  17. Insider protection technology developments

    Energy Technology Data Exchange (ETDEWEB)

    Foesch, J.; Bortniak, P.; Waddoups, I.

    1994-08-01

    Sandia National Laboratories evaluates and develops new techniques and technologies to ensure the integrity of special nuclear material (SNM) against potential insider threats. We have evaluated several types of sensor technologies and subsystems to monitor and/or track materials and personnel. This past year`s effort has been directed at characterizing commercial developments that meet the Department of Energy`s (DOE) needs in some of these areas. Some of these evaluations are complete and some are still in progress. This paper discusses our work with infrared light (IR), radio frequency (RF), and RF proximity technologies. After these technologies are judged to be applicable to DOE`s needs, we incorporate them into the generic, real time, personnel tracking and material monitoring system.

  18. Adaptive protection coordination scheme for distribution network with distributed generation using ABC

    Directory of Open Access Journals (Sweden)

    A.M. Ibrahim

    2016-09-01

    Full Text Available This paper presents an adaptive protection coordination scheme for optimal coordination of DOCRs in interconnected power networks with the impact of DG, the used coordination technique is the Artificial Bee Colony (ABC. The scheme adapts to system changes; new relays settings are obtained as generation-level or system-topology changes. The developed adaptive scheme is applied on the IEEE 30-bus test system for both single- and multi-DG existence where results are shown and discussed.

  19. Adaptive Flight Envelope Estimation and Protection Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Impact Technologies, in collaboration with the Georgia Institute of Technology, proposes to develop and demonstrate an innovative flight envelope estimation and...

  20. Adaptation to climate change: Legal challenges for protected areas

    NARCIS (Netherlands)

    Cliquet, An; Backes, Chris; Harris, Jim; Howsam, Peter

    2009-01-01

    Climate change will cause further loss of biodiversity. As negative effects are already taking place, adaptive measures are required to protect biodiversity from the effects of climate change. The EU policy on climate change and biodiversity aims at improving a coherent ecological network in order t

  1. Adaptive comanagement of a marine protected area network in Fiji.

    Science.gov (United States)

    Weeks, Rebecca; Jupiter, Stacy D

    2013-12-01

    Adaptive management of natural resources is an iterative process of decision making whereby management strategies are progressively changed or adjusted in response to new information. Despite an increasing focus on the need for adaptive conservation strategies, there remain few applied examples. We describe the 9-year process of adaptive comanagement of a marine protected area network in Kubulau District, Fiji. In 2011, a review of protected area boundaries and management rules was motivated by the need to enhance management effectiveness and the desire to improve resilience to climate change. Through a series of consultations, with the Wildlife Conservation Society providing scientific input to community decision making, the network of marine protected areas was reconfigured so as to maximize resilience and compliance. Factors identified as contributing to this outcome include well-defined resource-access rights; community respect for a flexible system of customary governance; long-term commitment and presence of comanagement partners; supportive policy environment for comanagement; synthesis of traditional management approaches with systematic monitoring; and district-wide coordination, which provided a broader spatial context for adaptive-management decision making. Co-Manejo Adaptativo de una Red de Áreas Marinas Protegidas en Fiyi. © 2013 The Authors. Conservation Biology published by Wiley Periodicals, Inc., on behalf of the Society for Conservation Biology.

  2. Development of environmental adaptable polymer

    Energy Technology Data Exchange (ETDEWEB)

    Yoshii, Fumio [Japan Atomic Energy Research Inst., Takasaki, Gunma (Japan). Takasaki Radiation Chemistry Research Establishment

    2000-09-01

    Biodegradable polymers were modified by radiation crosslinking tequniques to develop environmental adaptable polymer. Poly({epsilon}-caprolactone), OCL, (melting temperature, 60 deg C) by irradiation in the supercooled state led to the highest gel content and this polymer has high heat resistance. Relatively smaller dose such as 15 and 30 kGy were effective to improve process ability of aliphatic polyester by formation of branch structure during irradiation. It was found that sodium carboxymethyl cellulose (CMC-Na) with degree of substitution (DS) from 0.7 to 2.2 and sodium carboxymethyl starch (CMS-Na) with DS 0.15 caused crosslinking at past like condition by irradiation. The condition with higher concentration such as 50-60% was most effective for crosslinking of CMC-Na and CMS-Na. Crosslinked CMC-Na and CMS-Na formed hydrogel. PCL, CMC-Na, and CMS-Na had biodegradability even after crosslinking in irradiation. (author)

  3. Developing Organizational Adaptability for Complex Environment

    Science.gov (United States)

    Boylan, Steven A.; Turner, Kenneth A.

    2017-01-01

    Developing organizations capable of adapting requires leaders to set conditions. Setting conditions normally requires purposeful activities by the leadership to foster and develop leader and individual adaptability, supported by processes and activities that enable adaptive behaviors through the totality of the organization (Goldstein, Hazy, &…

  4. Adaptation funding and development assistance: some FAQs

    Energy Technology Data Exchange (ETDEWEB)

    Ayers, Jessica; Huq, Saleemul

    2008-11-15

    It's becoming ever clearer that development and climate change are intertwined issues. Unsustainable development drives climate change; sustainable development can reduce vulnerability to it. Development issues can constrain capacity to adapt to climate change; climate impacts can be a barrier to development. So adaptation to climate impacts is increasingly seen as part of good development practice – and development to improve the lives and resource access of people facing climate challenges is viewed as a prerequisite for successful adaptation. But when it comes to adaptation funding, confusion and contention remain over the role development institutions play.

  5. Adaptive Overcurrent Protection for Microgrids in Extensive Distribution Systems

    DEFF Research Database (Denmark)

    Lin, Hengwei; Guerrero, Josep M.; Jia, Chenxi

    2016-01-01

    is treated as a linear programming problem for the different operation states. In the control center, an artificial neural network (ANN) model is trained with real-time measurements to identify the states whether there is a fault on the line segment. Fault location is estimated further with the same......Microgrid is regarded as a new form to integrate the increasing penetration of distributed generation units (DGs) in the extensive distribution systems. This paper proposes an adaptive overcurrent protection strategy for a microgrid network. The protection coordination of the overcurrent relays...

  6. 德国适应气候变化与保护气候的城市规划发展实践%Adaptive Urban Rural Planning Development For Climate Change And Protection In Germany

    Institute of Scientific and Technical Information of China (English)

    魏薇; 秦洛峰

    2012-01-01

    Global climate change Is an imperative issue which requires urban planning response. In Germany, planners establishes climate change zoning model, studies a series of climate adaptive development strategies, makes climate adaptive regional and city planning, which includes encouraging public, pedestrian, and bicycle transportation, advocating land saving neighborhood structure, climate protective layout and site choice. These can be references for China's urban planning development.%全球气候变化正在成为当前世界最紧迫的环境问题,城市规划对减弱气候变化影响和保护气候具有决定意义.德国为应对气候变化,从构建气候变化区域模型入手,探讨了一系列气候适应性发展策略,开展了气候适应性区域规划和城市规划实践,如减少交通出行,鼓励公共交通、步行和自行车交通,倡导节约用地的居住区结构及有利于气候保护的功能布局和建设用地选址,为我国气候适应性规划提供了借鉴.

  7. Connecting climate social adaptation and land use change in internationally adjoining protected areas

    Directory of Open Access Journals (Sweden)

    Claudia Rodríguez Solórzano

    2016-01-01

    Full Text Available The development of climate adaptation strategies to address social problems derived from climate change is pressing. Yet, in addition to providing means to minimise the impact of climate variability and change on livelihoods, climate adaptation strategies might exacerbate environmental change and cause negative social impacts. Systematic research has not addressed the impacts of adaptation on environmental change. In this paper, I focus on land use change as a specific type of environmental change and on three adaptation strategies: diversification, pooling and out-migration. I analyse the influence of adaptation strategies on land use change by drawing on interviews with the managers of 56 internationally adjoining protected areas in 18 countries in the Americas. The findings indicate that the impact of adaptation depends on the adaptation strategy people choose. When people out-migrate, land use change increases. Community elite control for decision-making, shorter distances between communities and markets and more communities in and around the protected areas also increase land use change. These findings show that adaptation can be a driver of further environmental change, and thus further study is needed to understand the likely impacts of adaptation on conservation.

  8. The role of Toll-like receptors and adaptive immunity in the development of protective or pathological immune response triggered by the Trypanosoma cruzi protozoan.

    Science.gov (United States)

    Pellegrini, Andrea; Guiñazu, Natalia; Giordanengo, Laura; Cano, Roxana Carolina; Gea, Susana

    2011-12-01

    Trypanosoma cruzi, the causal agent of Chagas disease, is an intracellular protozoan parasite that predominantly invades macrophages and cardiomyocytes, leading to persistent infection. Several members of the Toll-like receptor family are crucial for innate immunity to infection and are involved in maintaining tissue homeostasis. This review focuses on recent experimental findings of the innate and adaptive immune response in controlling the parasite and/or in generating heart and liver tissue injury. We also describe the importance of the host's genetic background in the outcome of the disease and emphasize the importance of studying the response to specific parasite antigens. Understanding the dual participation of the immune response may contribute to the design of new therapies for Chagas disease.

  9. Adaptation to Climate Change in Developing Countries

    DEFF Research Database (Denmark)

    Mertz, Ole; Halsnæs, Kirsten; Olesen, Jørgen E.

    2009-01-01

    Adaptation to climate change is given increasing international attention as the confidence in climate change projections is getting higher. Developing countries have specific needs for adaptation due to high vulnerabilities, and they will in this way carry a great part of the global costs...... of climate change although the rising atmospheric greenhouse gas concentrations are mainly the responsibility of industrialized countries. This article provides a status of climate change adaptation in developing countries. An overview of observed and projected climate change is given, and recent literature...... on impacts, vulnerability, and adaptation are reviewed, including the emerging focus on mainstreaming of climate change and adaptation in development plans and programs. The article also serves as an introduction to the seven research articles of this special issue on climate change adaptation in developing...

  10. Adaptation to climate change in developing countries.

    Science.gov (United States)

    Mertz, Ole; Halsnaes, Kirsten; Olesen, Jørgen E; Rasmussen, Kjeld

    2009-05-01

    Adaptation to climate change is given increasing international attention as the confidence in climate change projections is getting higher. Developing countries have specific needs for adaptation due to high vulnerabilities, and they will in this way carry a great part of the global costs of climate change although the rising atmospheric greenhouse gas concentrations are mainly the responsibility of industrialized countries. This article provides a status of climate change adaptation in developing countries. An overview of observed and projected climate change is given, and recent literature on impacts, vulnerability, and adaptation are reviewed, including the emerging focus on mainstreaming of climate change and adaptation in development plans and programs. The article also serves as an introduction to the seven research articles of this special issue on climate change adaptation in developing countries. It is concluded that although many useful steps have been taken in the direction of ensuring adequate adaptation in developing countries, much work still remains to fully understand the drivers of past adaptation efforts, the need for future adaptation, and how to mainstream climate into general development policies.

  11. Analysis of a Major Electric Grid -- Stability and Adaptive Protection

    Science.gov (United States)

    Alanzi, Sultan

    Protective systems of the electric grid are designed to detect and mitigate the effects of faults and other disturbances that may occur. Distance relays are used extensively for the detection of faults on transmission lines. Out-of-step relays are used for generator protection to detect loss of synchronism conditions that result from disturbances on the electric grid. Also, when a disturbance occurs and generators may tend to lose synchronism with each other, it is beneficial to separate the overall system into several independent systems that can remain stable. Unfortunately there have been cases, such as the 2003 Northeast blackout where the operation of protective relays, namely the zone 3 distance relay used for transmission line protection, contributed to the cascading effect of the blackout. It is the objective of this dissertation to propose adaptive relays for both distance protection of transmission lines and out-of-step protection of generators. By being adaptive, the relays are made aware of the system operating conditions and can adjust its settings accordingly. Inputs to the adaptive logic can come from system or environmental conditions. As a result of this effort, a new distance relay operating characteristic is proposed, referred to as a mushroom relay, which is a combination of a quadrilateral relay and a Mho relay. Also, a new criterion for determining if a power swing following a disturbance is stable or unstable is proposed. Distance protection of transmission lines is very important when discussing system responses to faults and disturbances. Distance relays are very common worldwide and although they offer great protection, there are limitations that need to be addressed. Parallel line operations (infeed effect) and the loadability limits are among the limitations that lead to improper response of relays. An Adaptive Distance Relays (ADR) offer great benefits to the protection scheme as their settings can be changed in accordance with prefault

  12. Reliable Software Development for Machine Protection Systems

    CERN Document Server

    Anderson, D; Dragu, M; Fuchsberger, K; Garnier, JC; Gorzawski, AA; Koza, M; Krol, K; Misiowiec, K; Stamos, K; Zerlauth, M

    2014-01-01

    The Controls software for the Large Hadron Collider (LHC) at CERN, with more than 150 millions lines of code, resides amongst the largest known code bases in the world1. Industry has been applying Agile software engineering techniques for more than two decades now, and the advantages of these techniques can no longer be ignored to manage the code base for large projects within the accelerator community. Furthermore, CERN is a particular environment due to the high personnel turnover and manpower limitations, where applying Agile processes can improve both, the codebase management as well as its quality. This paper presents the successful application of the Agile software development process Scrum for machine protection systems at CERN, the quality standards and infrastructure introduced together with the Agile process as well as the challenges encountered to adapt it to the CERN environment.

  13. Professional Development to Promote Teacher Adaptability

    Science.gov (United States)

    Parsons, Allison Ward; Ankrum, Julie Winneur; Morewood, Aimee

    2016-01-01

    Effective professional development (PD) follows adaptive teaching principles; it increases teacher understanding and instructional purpose, which ultimately supports and extends adaptive teaching. Through this article, we compare and contrast training models with educative models of PD (Duffy, 2004). We discuss characteristics of effective PD that…

  14. Leveraging modern climatology to increase adaptive capacity across protected area networks

    Science.gov (United States)

    Davison, J.E.; Graumlich, L.J.; Rowland, E.L.; Pederson, G.T.; Breshears, D.D.

    2012-01-01

    Human-driven changes in the global environment pose an increasingly urgent challenge for the management of ecosystems that is made all the more difficult by the uncertain future of both environmental conditions and ecological responses. Land managers need strategies to increase regional adaptive capacity, but relevant and rapid assessment approaches are lacking. To address this need, we developed a method to assess regional protected area networks across biophysically important climatic gradients often linked to biodiversity and ecosystem function. We plot the land of the southwestern United States across axes of historical climate space, and identify landscapes that may serve as strategic additions to current protected area portfolios. Considering climate space is straightforward, and it can be applied using a variety of relevant climate parameters across differing levels of land protection status. The resulting maps identify lands that are climatically distinct from existing protected areas, and may be utilized in combination with other ecological and socio-economic information essential to collaborative landscape-scale decision-making. Alongside other strategies intended to protect species of special concern, natural resources, and other ecosystem services, the methods presented herein provide another important hedging strategy intended to increase the adaptive capacity of protected area networks. ?? 2011 Elsevier Ltd.

  15. Developing a Radiation Protection Hub

    Energy Technology Data Exchange (ETDEWEB)

    Hertel, Nolan E [ORNL

    2017-01-01

    The WARP report issued by the NCRP study committee estimates that in ten years there will be a human capital crisis across the radiation safety community. The ability to respond to this shortage will be amplified by the fact that many radiation protection (health physics) academic programs will find it difficult to justify their continued existence since they are low volume programs, both in terms of enrollment and research funding, compared to the research funding return and visibility of more highly subscribed and highly funded academic disciplines. In addition, across the national laboratory complex, radiation protection research groups have been disbanded or dramatically reduced in size. The loss of both of these national resources is being accelerated by low and uncertain government funding priorities. The most effective solution to this problem would be to form a consortium that would bring together the radiation protection research, academic and training communities. The goal of such a consortium would be to engage in research, education and training of the next generation of radiation protection professionals. Furthermore the consortium could bring together the strengths of different universities, national laboratory programs and other entities in a strategic manner to accomplish a multifaceted research, educational and training agenda. This vision would forge a working and funded relationship between major research universities, national labs, four-year degree institutes, technical colleges and other partners.

  16. Mobilising private adaptation finance: developed country perspectives

    NARCIS (Netherlands)

    Pauw, W.P.

    2017-01-01

    Abstract The private sector is one of the sources of finance included in developed countries’ pledge in the UN climate negotiations to mobilise $100 billion annually by 2020 to support developing countries’ efforts to address climate change. For adaptation in particular, it remains unclear what

  17. Developing Adaptive Elearning: An Authoring Tool Design

    Directory of Open Access Journals (Sweden)

    Said Talhi

    2011-09-01

    Full Text Available Adaptive hypermedia is the answer to the lost in hyperspace syndrome, where the user has normally too many links to choose from, and little knowledge about how to proceed and select the most appropriate ones to him/her. Adaptive hypermedia thus offers a selection of links or content most appropriate to the user. Until very recently, little attention has been given to the complex task of authoring materials for Adaptive Educational Hypermedia. An author faces a multitude of problems when creating a personalized, rich learning experience for each user. The purpose of this paper is to present an authoring tool for adaptive hypermedia based courses. Designed to satisfy guidelines of accessibility of the W3C recommendation for authors and learners that present disabilities, the authoring tool allows several authors geographically dispersed to produce such courses together. It consists of a shared workspace gathering all tools necessary to the cooperative development task.

  18. Thailand - Country Development Partnership : Social Protection

    OpenAIRE

    World Bank

    2002-01-01

    The Thailand Country Development Partnership for Social Protection (CDP-SP) is a collaborative program of policy development and technical assistance between the Ministry of Labor and Social Protection and the Bank and was launched in July 2001. CDP-SP operates in three key policy areas: labor markets; social insurance; and social assistance and safety nets. This report reviews the objecti...

  19. Climate change and river ecosystems: protection and adaptation options.

    Science.gov (United States)

    Palmer, Margaret A; Lettenmaier, Dennis P; Poff, N Leroy; Postel, Sandra L; Richter, Brian; Warner, Richard

    2009-12-01

    Rivers provide a special suite of goods and services valued highly by the public that are inextricably linked to their flow dynamics and the interaction of flow with the landscape. Yet most rivers are within watersheds that are stressed to some extent by human activities including development, dams, or extractive uses. Climate change will add to and magnify risks that are already present through its potential to alter rainfall, temperature, runoff patterns, and to disrupt biological communities and sever ecological linkages. We provide an overview of the predicted impacts based on published studies to date, discuss both reactive and proactive management responses, and outline six categories of management actions that will contribute substantially to the protection of valuable river assets. To be effective, management must be place-based focusing on local watershed scales that are most relevant to management scales. The first priority should be enhancing environmental monitoring of changes and river responses coupled with the development of local scenario-building exercises that take land use and water use into account. Protection of a greater number of rivers and riparian corridors is essential, as is conjunctive groundwater/surface water management. This will require collaborations among multiple partners in the respective river basins and wise land use planning to minimize additional development in watersheds with valued rivers. Ensuring environmental flows by purchasing or leasing water rights and/or altering reservoir release patterns will be needed for many rivers. Implementing restoration projects proactively can be used to protect existing resources so that expensive reactive restoration to repair damage associated with a changing climate is minimized. Special attention should be given to diversifying and replicating habitats of special importance and to monitoring populations at high risk or of special value so that management interventions can occur if the

  20. Fully Adaptive Radar Modeling and Simulation Development

    Science.gov (United States)

    2017-04-01

    Organization (NATO) Sensors Electronics Technology (SET)-227 Panel on Cognitive Radar. The FAR M&S architecture developed in Phase I allows for...Air Force’s previously developed radar M&S tools. This report is organized as follows. In Chapter 3, we provide an overview of the FAR framework...AFRL-RY-WP-TR-2017-0074 FULLY ADAPTIVE RADAR MODELING AND SIMULATION DEVELOPMENT Kristine L. Bell and Anthony Kellems Metron, Inc

  1. The development of the Swiss Adaptation Strategy

    Science.gov (United States)

    Hohmann, R.; Köllner-Heck, P.; Probst, T.

    2010-09-01

    In summer 2009, the Federal Council mandated the Departement of the Environment, Transport, Energy and Communication (DETEC) to develop a Swiss adaptation strategy. This strategy aims to coordinate the efforts of all federal departments involved in adaptation, and to provide them with the necessary basic information. For the development of the Swiss adaptation strategy the following principles are fundamental. (1.) The strategy aims to achieve the overarching objectives of harnessing the opportunities that climate change presents, minimizing the risks of climate change to people and assets, and to increases the adaptive capacity of all resources. (2) The strategy is based on the most recent scientific knowledge about climate change and climate change impacts. (3.) It is based in on a sound and comprehensive analysis of climate change risks. (4.) It includes strategic goals for the sectors that are most vulnerable to climate change, i.e., water management, biodiversity management, agriculture, forestry, natural hazard prevention, health care, energy generation, tourism, land use. (5.) It thoroughly analyzes the interfaces between the sectoral strategies in order solve existing conflicts and profit form existing synergies. The Swiss Adaptation Strategy will be completed and submitted to the Federal Council by the End of 2011.

  2. [Adaptive clinical study methodologies in drug development].

    Science.gov (United States)

    Antal, János

    2015-11-29

    The evolution of drug development in human, clinical phase studies triggers the overview of those technologies and procedures which are labelled as adaptive clinical trials. The most relevant procedural and operational aspects will be discussed in this overview from points of view of clinico-methodological aspect.

  3. [Development of an adaptive pneumatic tourniquet].

    Science.gov (United States)

    Liu, Hongyun; Zhang, Zhengbo; Li, Kaiyuan; Guo, Junyan; Wang, Weidong

    2012-06-01

    A new adaptive pneumatic tourniquet was developed for limb operation and first-aid. The crucial hardware circuits of the adaptive pneumatic tourniquet were designed based on the microprocessor C8051F340 and blood pressure module CSN602, software was programmed and an experiment was carried out for verifying the system. Results showed that the prototype could measure accurately systolic blood pressure, heart rate and other relative parameters and the designed device could adjust tourniquet cuff's pressure through inflation and deflation according to systolic blood pressure and limb circumference. This designed system integrated the advantages of the adaptive pneumatic tourniquet, and could be used for controlling life-threatening extremity hemorrhage operation and maintaining a bloodless opeation field.

  4. Development of adaptive helicopter seat systems for aircrew vibration mitigation

    Science.gov (United States)

    Chen, Yong; Wickramasinghe, Viresh; Zimcik, David G.

    2008-03-01

    Helicopter aircrews are exposed to high levels of whole body vibration during flight. This paper presents the results of an investigation of adaptive seat mount approaches to reduce helicopter aircrew whole body vibration levels. A flight test was conducted on a four-blade helicopter and showed that the currently used passive seat systems were not able to provide satisfactory protection to the helicopter aircrew in both front-back and vertical directions. Long-term exposure to the measured whole body vibration environment may cause occupational health issues such as spine and neck strain injuries for aircrew. In order to address this issue, a novel adaptive seat mount concept was developed to mitigate the vibration levels transmitted to the aircrew body. For proof-of-concept demonstration, a miniature modal shaker was properly aligned between the cabin floor and the seat frame to provide adaptive actuation authority. Adaptive control laws were developed to reduce the vibration transmitted to the aircrew body, especially the helmet location in order to minimize neck and spine injuries. Closed-loop control test have been conducted on a full-scale helicopter seat with a mannequin configuration and a large mechanical shaker was used to provide representative helicopter vibration profiles to the seat frame. Significant vibration reductions to the vertical and front-back vibration modes have been achieved simultaneously, which verified the technical readiness of the adaptive mount approach for full-scale flight test on the vehicle.

  5. Development of fault tolerant adaptive control laws for aerospace systems

    Science.gov (United States)

    Perez Rocha, Andres E.

    The main topic of this dissertation is the design, development and implementation of intelligent adaptive control techniques designed to maintain healthy performance of aerospace systems subjected to malfunctions, external parameter changes and/or unmodeled dynamics. The dissertation is focused on the development of novel adaptive control configurations that rely on non-linear functions that appear in the immune system of living organisms as main source of adaptation. One of the main goals of this dissertation is to demonstrate that these novel adaptive control architectures are able to improve overall performance and protect the system while reducing control effort and maintaining adequate operation outside bounds of nominal design. This research effort explores several phases, ranging from theoretical stability analysis, simulation and hardware implementation on different types of aerospace systems including spacecraft, aircraft and quadrotor vehicles. The results presented in this dissertation are focused on two main adaptivity approaches, the first one is intended for aerospace systems that do not attain large angles and use exact feedback linearization of Euler angle kinematics. A proof of stability is presented by means of the circle Criterion and Lyapunov's direct method. The second approach is intended for aerospace systems that can attain large attitude angles (e.g. space systems in gravity-less environments), the adaptation is incorporated on a baseline architecture that uses partial feedback linearization of quaternions kinematics. In this case, the closed loop stability was analyzed using Lyapunov's direct method and Barbalat's Lemma. It is expected that some results presented in this dissertation can contribute towards the validation and certification of direct adaptive controllers.

  6. Development of large aperture composite adaptive optics

    Science.gov (United States)

    Kmetik, Viliam; Vitovec, Bohumil; Jiran, Lukas; Nemcova, Sarka; Zicha, Josef; Inneman, Adolf; Mikulickova, Lenka; Pavlica, Richard

    2015-01-01

    Large aperture composite adaptive optics for laser applications is investigated in cooperation of Institute of Plasma Physic, Department of Instrumentation and Control Engineering FME CTU and 5M Ltd. We are exploring opportunity of a large-size high-power-laser deformable-mirror production using a lightweight bimorph actuated structure with a composite core. In order to produce a sufficiently large operational free aperture we are developing new technologies for production of flexible core, bimorph actuator and deformable mirror reflector. Full simulation of a deformable-mirrors structure was prepared and validated by complex testing. A deformable mirror actuation and a response of a complicated structure are investigated for an accurate control of the adaptive optics. An original adaptive optics control system and a bimorph deformable mirror driver were developed. Tests of material samples, components and sub-assemblies were completed. A subscale 120 mm bimorph deformable mirror prototype was designed, fabricated and thoroughly tested. A large-size 300 mm composite-core bimorph deformable mirror was simulated and optimized, fabrication of a prototype is carried on. A measurement and testing facility is modified to accommodate large sizes optics.

  7. ECONOMIC DEVELOPMENT VS PROTECTION OF ETHNIC CULTURES

    Institute of Scientific and Technical Information of China (English)

    郑茜; 李晓勤

    2004-01-01

    In November 2004,on international symposium was held in Kunming capital of southwest China's Yunnan Province,on economic development vs.protection of China's ethnic cultures.Participants agreed that the gathering came in good time in view of the fact that economic development is posing a growing threat to the very existence of ethnic cultures.

  8. Development of the Embedded Protective Device Based on ARM

    Institute of Scientific and Technical Information of China (English)

    LIU Xiao-wen; LI Na; PAN Chun-de

    2005-01-01

    An embedded protective device for 35kV power line is worked out based on Philips' LPC2292 ARM MCU. Several aspects such as embedded design technique adopted in the system framework, application of adaptive theory in data acquisition, Board Support Packet (BSP) developing and task dispatching related to operating system are discussed. Both hardware and software framework of the system are given. Advanced hardware platform and software development environment is applied in design of the system, with the advanced co-design technology.

  9. Developing More Adaptable Individuals and Institutions

    Science.gov (United States)

    2010-02-01

    interact with each other. And leaders must prepare to respond adaptively, with “new attitudes, mindsets, and 2 Mink Spaans, Maartje Spoelstra, Erik... innovative and adaptive leaders down to the lowest levels… [and] Improv[ing] Service and institutional adaptability to deal with rapid change. 11...Generally recognized adaptability skills such as critical thinking, self- awareness, and various social skills have universal applicability

  10. Is prevention of acute pesticide poisoning effective and efficient, with Locally Adapted Personal Protective Equipment?

    DEFF Research Database (Denmark)

    Varma, Anshu; Neupane, Dinesh; Ellekilde Bonde, Jens Peter

    2016-01-01

    BACKGROUND: Farmers' risk of pesticide poisoning can be reduced with personal protective equipment but in low-income countries farmers' use of such equipment is limited. OBJECTIVE: To examine the effectiveness and efficiency of Locally Adapted Personal Protective Equipment to reduce organophospha...

  11. Is prevention of acute pesticide poisoning effective and efficient, with Locally Adapted Personal Protective Equipment?

    DEFF Research Database (Denmark)

    Varma, Anshu; Neupane, Dinesh; Ellekilde Bonde, Jens Peter;

    2016-01-01

    BACKGROUND: Farmers' risk of pesticide poisoning can be reduced with personal protective equipment but in low-income countries farmers' use of such equipment is limited. OBJECTIVE: To examine the effectiveness and efficiency of Locally Adapted Personal Protective Equipment to reduce organophospha...

  12. Normal adaptations to exercise despite protection against oxidative stress.

    Science.gov (United States)

    Higashida, Kazuhiko; Kim, Sang Hyun; Higuchi, Mitsuru; Holloszy, John O; Han, Dong-Ho

    2011-11-01

    It has been reported that supplementation with the antioxidant vitamins C and E prevents the adaptive increases in mitochondrial biogenesis and GLUT4 expression induced by endurance exercise. We reevaluated the effects of these antioxidants on the adaptive responses of rat skeletal muscle to swimming in a short-term study consisting of 9 days of vitamins C and E with exercise during the last 3 days and a longer-term study consisting of 8 wk of antioxidant vitamins with exercise during the last 3 wk. The rats in the antioxidant groups were given 750 mg·kg body wt(-1)·day(-1) vitamin C and 150 mg·kg body wt(-1)·day(-1) vitamin E. In rats euthanized immediately after exercise, plasma TBARs were elevated in the control rats but not in the antioxidant-supplemented rats, providing evidence for an antioxidant effect. In rats euthanized 18 h after exercise there were large increases in insulin responsiveness of glucose transport in epitrochlearis muscles mediated by an approximately twofold increase in GLUT4 expression in both the short- and long-term treatment groups. The protein levels of a number of mitochondrial marker enzymes were also increased about twofold. Superoxide dismutases (SOD) 1 and 2 were increased about twofold in triceps muscle after 3 days of exercise, but only SOD2 was increased after 3 wk of exercise. There were no differences in the magnitudes of any of these adaptive responses between the control and antioxidant groups. These results show that very large doses of antioxidant vitamins do not prevent the exercise-induced adaptive responses of muscle mitochondria, GLUT4, and insulin action to exercise and have no effect on the level of these proteins in sedentary rats.

  13. A DSP-Based Beam Current Monitoring System for Machine Protection Using Adaptive Filtering

    Energy Technology Data Exchange (ETDEWEB)

    J. Musson; H. Dong; R. Flood; C. Hovater; J. Hereford

    2001-06-01

    The CEBAF accelerator at Jefferson Lab is currently using an analog beam current monitoring (BCM) system for its machine protection system (MPS), which has a loss accuracy of 2 micro-amps. Recent burn-through simulations predict catastrophic beam line component failures below 1 micro-amp of loss, resulting in a blind spot for the MPS. Revised MPS requirements target an ultimate beam loss accuracy of 250 nA. A new beam current monitoring system has been developed which utilizes modern digital receiver technology and digital signal processing concepts. The receiver employs a direct-digital down converter integrated circuit, mated with a Jefferson Lab digital signal processor VME card. Adaptive filtering is used to take advantage of current-dependent burn-through rates. Benefits of such a system include elimination of DC offsets, generic algorithm development, extensive filter options, and interfaces to UNIX-based control systems.

  14. Is prevention of acute pesticide poisoning effective and efficient, with Locally Adapted Personal Protective Equipment? A randomized crossover study among farmers in Chitwan, Nepal

    DEFF Research Database (Denmark)

    Varma, Anshu; Neupane, Dinesh; Bonde, Jens Peter Ellekilde

    2016-01-01

    . Based on the farmers' working behavior, compounds used, intensity and exposure duration we conclude that Locally Adapted Personal Protective Equipment does not provide additional protection during usual work practices. However, our Locally Adapted Personal Protective Equipment might offer protection...

  15. Stability of sublethal acid stress adaptation and induced cross protection against lauric arginate in Listeria monocytogenes.

    Science.gov (United States)

    Shen, Qian; Soni, Kamlesh A; Nannapaneni, Ramakrishna

    2015-06-16

    The stability of acid stress adaptation in Listeria monocytogenes and its induced cross protection effect against GRAS (generally recognized as safe) antimicrobial compounds has never been investigated before. In the present study, the acid stress adaptation in L. monocytogenes was initially induced in pH 5.0 tryptic soy broth supplemented with 0.6% yeast extract (TSB-YE) at 37 °C. Subsequently, the stability of acid stress adaptation, which was defined as the capacity to maintain its acquired acid adaptation after induction in the absence of sublethal acid stress, was determined at 37 °C, 22 °C or 4 °C in broth and in different food substrates. Then, the acid stress adaptation induced cross protection against lauric arginate (LAE) and its stability was investigated in TSB-YE, milk and carrot juice. Our findings show that the acid stress adaptation was stable at 4 °C up to 24h but was reversed at 37 °C or 22 °C within 2h. In the cross protection assay with LAE, the acid stress adapted cells had approximately 2 log CFU/ml greater survival than non-adapted cells in broth at 22 °C or in milk and carrot juice at 4 °C. The acid adaptation induced cross protection against LAE in L. monocytogenes was reversible within 1h at 4 °C in the absence of sublethal acid stress. Our findings suggest that the stability of acid adaptation in L. monocytogenes under cold conditions should be taken into account when the risk analysis is performed during food processing.

  16. Development of radiation protection and measurement technology

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Si Young; Lee, T. Y.; Kim, J. L.; Kim, B. H.; Lee, B. J.; Chung, K. K.; Lee, K. C.; Chung, R. I.; Han, Y. D.; Kim, J. S.; Lee, H. S.; Kim, C. K.; Yoon, K. S.; Jeong, D. Y.; Yoon, S. C.; Yoon, Y. C.; Lee, S. Y.; Kim, J. S.; Seo, K. W. [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Kim, J. K.; Lee, J. K. [Hanyang Univ., Seoul (Korea, Republic of)

    1997-07-01

    Reference X-, gamma, beta and neutron radiation fields complying with the ISO and ANSI standards have been established and evaluated to provide a basic technical support in national radiation protection dosimetry program and to provide calibration measurement devices. Personal dose evaluation algorithm has been developed with these reference radiation fields, which comply well with both domestic and the new ANSI N13.11, to evaluate accurate personal dose equivalents. A personal internal dosimetry algorithm which can estimate the intakes of radionuclides from the results of in vivo bioassay and the resulting internal doses has been developed and verified its performance. It was also evaluated to be equality excellent compared with those being used in foreign countries and used to make a computer code for internal dose evaluation which can be run with PC under the Windows environment. A BOMAB phantom for precise calibration of in vivo system has been also designed, fabricated and test-evaluated. Based on the ALARA concept of the optimization principle of radiation protection, a method for estimating the cost for radiation protection has been studied and an objective monetary cost of detriment due to radiation exposure, called {alpha} value ($/man-Sv) has been derived and proposed based on the Korean socio-economic situation and human risk factors to provide basic data for the radiation protection optimization study in Korea. (author). 100 refs., 104 tabs., 69 figs.

  17. An Adaptive Watermarking Technique for Copyright Protection of Digital Images

    Energy Technology Data Exchange (ETDEWEB)

    Park, K.S.; Lee, B.Y.; Park, S.H. [Yonsei University, Seoul (Korea); Chung, T.Y. [Kangnung National University, Kangnung (Korea)

    2002-03-01

    This paper proposes a new watermark embedding and extraction technique which extends the direct sequence spread spectrum technique. The proposed technique approximates the complexity of image and block in spatial domain using Laplacian filtering and watermark is adaptively embeded in the mid-frequency DCT components. Local parity bits are attached to higher-frequency DCT components and they are used to detect extraction errors and correct those errors. In extraction process, the proposed method boosts the higher frequency components of image and extracts the watermark by demodulation and this information is verified and adjusted by parity bits. Experimental results show it is invisible and robust to several external attacks. (author). 7 refs., 5 figs., 2 tabs.

  18. Environmental Protection and Sustainable Development Strategy

    OpenAIRE

    Brasoveanu Florica

    2013-01-01

    Since 1970 after scientific discoveries about the ozone hole humanity began to reconsider the environment. Environmental messages had different intensities depending on their sources Scientific messages proved the harshest, the political ones had a powerful declarative impact, but the administrative apparatus, both worldwide and local didn't turn very perceptive. Towards the implementation of actions to protect the environment and sustainable development economic and social factors intervened...

  19. Implementing new flood protection standards: obstacles to adaptive management and how to overcome these

    Directory of Open Access Journals (Sweden)

    Klijn Frans

    2016-01-01

    Full Text Available The Netherlands is updating its flood protection, whilst fully taking into account climate change and socioeconomic development. This translates in ‘anticipatory standards’ which need to be met in 2050, and which apply for the then foreseen climate and economy. Whilst the government maintains to have adopted a policy of adaptive planning and management, the new standards are thus based on one future situation, which qualifies as a ‘high end scenario’ from a flood risk management perspective. The consequences of adopting these new standards are now becoming clear. It is expected that many hundreds of kilometres of primary flood defences need to be reinforced and/or raised, at an estimated investment of about 9-14 billion euros. The many uncertainties about actual future development, however, complicate the decision making about the implementation of individual reinforcement projects: should one aim at immediately meeting the new standard or gradually improve and grow towards it? In this paper we discuss the uncertain decision making context, show that lawfulness (working according to procedures, rules and regulations and expediency (towards a purpose may jeopardize the good intentions of adaptive management, and argue that optimization may not provide the most useful answer to this decision making problem.

  20. An Adaptive Systematic Lossy Error Protection Scheme for Broadcast Applications Based on Frequency Filtering and Unequal Picture Protection

    Directory of Open Access Journals (Sweden)

    Marie Ramon

    2009-01-01

    Full Text Available Systematic lossy error protection (SLEP is a robust error resilient mechanism based on principles of Wyner-Ziv (WZ coding for video transmission over error-prone networks. In an SLEP scheme, the video bitstream is separated into two parts: a systematic part consisting of a video sequence transmitted without channel coding, and additional information consisting of a WZ supplementary stream. This paper presents an adaptive SLEP scheme in which the WZ stream is obtained by frequency filtering in the transform domain. Additionally, error resilience varies adaptively depending on the characteristics of compressed video. We show that the proposed SLEP architecture achieves graceful degradation of reconstructed video quality in the presence of increasing transmission errors. Moreover, it provides good performances in terms of error protection as well as reconstructed video quality if compared to solutions based on coarser quantization, while offering an interesting embedded scheme to apply digital video format conversion.

  1. Application of Advanced Wide Area Early Warning Systems with Adaptive Protection

    Energy Technology Data Exchange (ETDEWEB)

    Blumstein, Carl [Univ. of California, Berkeley, CA (United States); Cibulka, Lloyd [Univ. of California, Berkeley, CA (United States); Thorp, James [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Centeno, Virgilio [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); King, Roger [Mississippi State Univ., Mississippi State, MS (United States); Reeves, Kari [Mississippi State Univ., Mississippi State, MS (United States); Ashrafi, Frank [Southern California Edison Co., Rosemead, CA (United States); Madani, Vahid [Pacific Gas & Electric Co., San Francisco, CA (United States)

    2014-09-30

    Recent blackouts of power systems in North America and throughout the world have shown how critical a reliable power system is to modern societies, and the enormous economic and societal damage a blackout can cause. It has been noted that unanticipated operation of protection systems can contribute to cascading phenomena and, ultimately, blackouts. This project developed and field-tested two methods of Adaptive Protection systems utilizing synchrophasor data. One method detects conditions of system stress that can lead to unintended relay operation, and initiates a supervisory signal to modify relay response in real time to avoid false trips. The second method detects the possibility of false trips of impedance relays as stable system swings “encroach” on the relays’ impedance zones, and produces an early warning so that relay engineers can re-evaluate relay settings. In addition, real-time synchrophasor data produced by this project was used to develop advanced visualization techniques for display of synchrophasor data to utility operators and engineers.

  2. Climate change adaptation in Ethiopia: to what extent does social protection influence livelihood diversification?

    DEFF Research Database (Denmark)

    Weldegebriel, Zerihun; Prowse, Martin Philip

    2013-01-01

    Social-protection programmes like the Productive Safety-Net Programme (PSNP) in Ethiopia can play a positive role in promoting livelihoods and enhancing risk management. This article uses propensity score matching to estimate its effect on income diversification. The results suggest that receivin...... in a positive manner for climate adaptation. The article concludes by arguing for the promotion of positive forms of income diversification and the further investigation of the PSNP’s influence on autonomous adaptation strategies....

  3. Development of a Crop Adapted Spray Application (CASA) sprayer for orchards

    NARCIS (Netherlands)

    Zande, van de J.C.; Doruchowski, G.; Balsari, P.; Wenneker, M.

    2010-01-01

    In the EU-FP6 ISAFRUIT project a Crop Adapted Spray Application system (CASA) for precision crop protection was developed (Doruchowski et al., 2009). The system ensures efficient and safe spray application in orchards according to actual needs and with respect to the environment. The developed CASA

  4. Development of a Crop Adapted Spray Application (CASA) sprayer for orchards

    NARCIS (Netherlands)

    Zande, van de J.C.; Doruchowski, G.; Balsari, P.; Wenneker, M.

    2010-01-01

    In the EU-FP6 ISAFRUIT project a Crop Adapted Spray Application system (CASA) for precision crop protection was developed (Doruchowski et al., 2009). The system ensures efficient and safe spray application in orchards according to actual needs and with respect to the environment. The developed CASA

  5. International and European Law on Protected Areas and Climate Change: Need for Adaptation or Implementation?

    Science.gov (United States)

    Cliquet, A.

    2014-10-01

    The protection and management of protected areas must be adapted to the effects of climate change. An important question is if the law on protected areas is capable of dealing with the required changes. In general, both international nature conventions and European Union nature conservation law do not contain any specific provisions on climate change and protected areas. Attention has been paid to this link in non-binding decisions and policy documents. In order to adapt the law to increased dynamics from climate change, more flexibility is needed. This flexibility should not be understood as "legal" flexibility, in the sense of the weakening nature conservation provisions. Scientific uncertainties on the effects of climate change might conflict with the need for legal certainties. In order to adapt to the effects of climate change, the two crucial elements are the strengthening of core protected areas and connectivity between the core areas. At the international level, both elements can be found in non-binding documents. International law enables the required adaptation; however, it often lacks concrete obligations. A stronger legal framework can be found at the level of the European Union. The Birds and Habitats Directives contain sufficient tools to deal with the effects of climate change. The Directives have been insufficiently implemented so far. Especially the central goals of reaching a favorable conservation status and connectivity measures need to be addressed much more in the future.

  6. International and European law on protected areas and climate change: need for adaptation or implementation?

    Science.gov (United States)

    Cliquet, A

    2014-10-01

    The protection and management of protected areas must be adapted to the effects of climate change. An important question is if the law on protected areas is capable of dealing with the required changes. In general, both international nature conventions and European Union nature conservation law do not contain any specific provisions on climate change and protected areas. Attention has been paid to this link in non-binding decisions and policy documents. In order to adapt the law to increased dynamics from climate change, more flexibility is needed. This flexibility should not be understood as "legal" flexibility, in the sense of the weakening nature conservation provisions. Scientific uncertainties on the effects of climate change might conflict with the need for legal certainties. In order to adapt to the effects of climate change, the two crucial elements are the strengthening of core protected areas and connectivity between the core areas. At the international level, both elements can be found in non-binding documents. International law enables the required adaptation; however, it often lacks concrete obligations. A stronger legal framework can be found at the level of the European Union. The Birds and Habitats Directives contain sufficient tools to deal with the effects of climate change. The Directives have been insufficiently implemented so far. Especially the central goals of reaching a favorable conservation status and connectivity measures need to be addressed much more in the future.

  7. Adaptive Protection Scheme for a Distribution System Considering Grid-Connected and Islanded Modes of Operation

    Directory of Open Access Journals (Sweden)

    Yavuz Ates

    2016-05-01

    Full Text Available The renewable energy-based distributed generation (DG implementation in power systems has been an active research area during the last few decades due to several environmental, economic and political factors. Although the integration of DG offers many advantages, several concerns, including protection schemes in systems with the possibility of bi-directional power flow, are raised. Thus, new protection schemes are strongly required in power systems with a significant presence of DG. In this study, an adaptive protection strategy for a distribution system with DG integration is proposed. The proposed strategy considers both grid-connected and islanded operating modes, while the adaptive operation of the protection is dynamically realized considering the availability of DG power production (related to faults or meteorological conditions in each time step. Besides, the modular structure and fast response of the proposed strategy is validated via simulations conducted on the IEEE 13-node test system.

  8. Development of the Specific Adaptation Mobility Cane.

    Science.gov (United States)

    Arrington, S.

    1995-01-01

    A travel cane was adapted for use by a 10-year-old boy with cortical blindness, severe mental retardation and cerebral palsy affecting his left arm and leg. The Specific Adaptation Mobility Cane utilizes the affected arm to hold the cane while leaving the other hand free for trailing walls, opening doors, carrying objects, and holding handrails.…

  9. Adaptive management theory development in the field of education.

    Directory of Open Access Journals (Sweden)

    Borova T.A.

    2011-07-01

    Full Text Available The article studies the development of the adaptive management theory in education systems. The methodology of the adaptive management theory is discussed and the essential characteristics of adaptive management theory that have changed in the context of higher education are highlighted. The comparative analysis of the adaptive management theory components in the field of education of adaptive management Ukrainian and Russian schools is carried out. Application of adaptive management theoretical grounds allows a smooth transition to teaching according to the humanistic principles.

  10. [An increase in efficiency of adaptations and a weakening of organism protective reactions in the process of biological evolution].

    Science.gov (United States)

    Ivanov, K P

    2014-01-01

    The main direction of evolution of living organisms is development of the central nervous system and sense organ, an increase of energy exchange development of homoiothermia, development of the more and more complex forms of behavior, an increase in energy expenditure in connection with an increase of the organism activity, and development of adaptation to the habitat. Such fundamental processes were subjected and have been subjected to numerous studies and discussions. However, in different animals there exist different species peculiarities of evolution of physiological functions, from which finally formed are fundamental evolutionary processes. We studied some of these specific processes by dividing them into two categories. The first category is "Increase of efficiency of adaptation" in development of biological evolution. By this term we mean development of amazing by perfection specific physiological mechanisms of adaptive character. The second category is "Weakening of protective organism reactions". By this we understand disturbance of protective mechanisms of the organism immune system, discoordination of movement of leukocytes along microvessels, the absence of efficient collateral circulation in brain and in heart, etc.

  11. Adaptation in the context of technology development and transfer

    DEFF Research Database (Denmark)

    Olhoff, Anne

    2015-01-01

    and transfer. It summarizes what technologies for adaptation are, how they relate to development, and what their role is in adaptation. It subsequently highlights a number of policy and research issues that could be important to inform future policy. The commentary has two key messages. First, it argues...... that informed policy decisions on technology development and transfer to enhance adaptation require systematic assessments of the findings in the theoretical and empirical literature. Second, in light of the potential for overlap between processes for adaptation and processes for technologies for adaptation......Starting from a summary of key developments under the United Nations Framework Convention on Climate Change (UNFCCC) related to adaptation and technologies, the commentary provides an initial review of the available literature relevant to adaptation in the context of technology development...

  12. Replanning Criteria and Timing Definition for Parotid Protection-Based Adaptive Radiation Therapy in Nasopharyngeal Carcinoma

    Directory of Open Access Journals (Sweden)

    Wei-Rong Yao

    2015-01-01

    Full Text Available The goal of this study was to evaluate real-time volumetric and dosimetric changes of the parotid gland so as to determine replanning criteria and timing for parotid protection-based adaptive radiation therapy in nasopharyngeal carcinoma. Fifty NPC patients were treated with helical tomotherapy; volumetric and dosimetric (Dmean, V1, and D50 changes of the parotid gland at the 1st, 6th, 11th, 16th, 21st, 26th, 31st, and 33rd fractions were evaluated. The clinical parameters affecting these changes were studied by analyses of variance methods for repeated measures. Factors influencing the actual parotid dose were analyzed by a multivariate logistic regression model. The cut-off values predicting parotid overdose were developed from receiver operating characteristic curves and judged by combining them with a diagnostic test consistency check. The median absolute value and percentage of parotid volume reduction were 19.51 cm3 and 35%, respectively. The interweekly parotid volume varied significantly (p<0.05. The parotid Dmean, V1, and D50 increased by 22.13%, 39.42%, and 48.45%, respectively. The actual parotid dose increased by an average of 11.38% at the end of radiation therapy. Initial parotid volume, initial parotid Dmean, and weight loss rate are valuable indicators for parotid protection-based replanning.

  13. Ultrasound in environmental protection - Recent developments

    Energy Technology Data Exchange (ETDEWEB)

    Mason, T.J. [Coventry University, Coventry (United Kingdom). School of Science and the Environment

    2002-07-01

    There can be little doubt that there is an increasing interest in the development of new methods for environmental protection and remediation. Driven by the interests of scientists and engineers but increasingly by legislation a very wide range of new technologies is being examined. Amongst these power ultrasound is proving to be a front-runner and offers a wide range of applications. Not all of these are likely to become industrial realities nevertheless there are a few which have a real chance of adoption. Some of the stronger contenders are reviewed below. (orig.)

  14. Adipose tissue and sustainable development: a connection that needs protection

    Directory of Open Access Journals (Sweden)

    Angelo eTremblay

    2015-05-01

    Full Text Available Obesity is generally considered as an excess body fat that increases the risk to develop ergonomic, metabolic and psychosocial problems. As suggested in this paper, body fat gain is also a protective adaptation that prevents body lipotoxicity, contributes to the secretion of molecules involved in metabolic regulation, and dilutes lipid soluble persistent organic pollutants (POPs. Recent literature shows that this protective role of adipose tissue is more solicited in a modern context in which unsuspected factors can affect energy balance to a much greater extent than what is generally perceived by health care professionals. These factors include short sleep duration, demanding mental work, and chemical pollution whose impact is more detectable in a context dominated by economic productivity and competitiveness. Since these factors might also include the increase in atmospheric CO2, it is likely that obesity prevention will need the support of a promotion in sustainable development, whether it is for human health and well-being or global ecological protection.

  15. Rhetorical Dissent as an Adaptive Response to Classroom Problems: A Test of Protection Motivation Theory

    Science.gov (United States)

    Bolkan, San; Goodboy, Alan K.

    2016-01-01

    Protection motivation theory (PMT) explains people's adaptive behavior in response to personal threats. In this study, PMT was used to predict rhetorical dissent episodes related to 210 student reports of perceived classroom problems. In line with theoretical predictions, a moderated moderation analysis revealed that students were likely to voice…

  16. Rhetorical Dissent as an Adaptive Response to Classroom Problems: A Test of Protection Motivation Theory

    Science.gov (United States)

    Bolkan, San; Goodboy, Alan K.

    2016-01-01

    Protection motivation theory (PMT) explains people's adaptive behavior in response to personal threats. In this study, PMT was used to predict rhetorical dissent episodes related to 210 student reports of perceived classroom problems. In line with theoretical predictions, a moderated moderation analysis revealed that students were likely to voice…

  17. Developing an undue influence screening tool for Adult Protective Services.

    Science.gov (United States)

    Quinn, Mary Joy; Nerenberg, Lisa; Navarro, Adria E; Wilber, Kathleen H

    2017-03-01

    The study purpose was to develop and pilot an undue influence screening tool for California's Adult Protective Services (APS) personnel based on the definition of undue influence enacted into California law January 1, 2014. Methods included four focus groups with APS providers (n = 33), piloting the preliminary tool by APS personnel (n = 15), and interviews with four elder abuse experts and two APS administrators. Social service literature-including existing undue influence models-was reviewed, as were existing screening and assessment tools. Using the information from these various sources, the California Undue Influence Screening Tool (CUIST) was developed. It can be applied to APS cases and potentially adapted for use by other professionals and for use in other states. Implementation of the tool into APS practice, policy, procedures, and training of personnel will depend on the initiative of APS management. Future work will need to address the reliability and validity of CUIST.

  18. Protecting Offshore Wind Turbines against Ship Impacts by Means of Adaptive Inflatable Structures

    Directory of Open Access Journals (Sweden)

    Cezary Graczykowski

    2009-01-01

    Full Text Available Collisions with small service ships are serious danger for offshore wind turbines. Installing torus-shaped adaptive inflatable structure that surrounds a wind turbine tower at water level is one method of effective protection. Proposed pneumatic structure contains several separate air chambers equipped with devices for fast inflation and pressure release. The system can be adapted to various impact scenarios by adjusting the level of initial pressure in each chamber and by controlling the release of compressed air during collision. The paper presents finite element simulation of ship collision with wind turbine tower protected by pneumatic structure, conducted using ABAQUS software. Introduced methods of pressure adjustment are aimed at mitigating tower and ship response. The performed feasibility study proves that inflatable structure can effectively protect the wind turbine tower and the ship against serious damage.

  19. Multi Agent System Based Adaptive Protection for Dispersed Generation Integrated Distribution Systems

    DEFF Research Database (Denmark)

    Liu, Leo; Rather, Zakir Hussain; Bak, Claus Leth

    2013-01-01

    The increasing penetration of dispersed generation (DG) brings challenges to conventional protection approaches of distribution system, mainly due to bi-directional power flow and variable fault current contribution from different generation technology-based DG units. Moreover, the trend of allow......The increasing penetration of dispersed generation (DG) brings challenges to conventional protection approaches of distribution system, mainly due to bi-directional power flow and variable fault current contribution from different generation technology-based DG units. Moreover, the trend......) is proposed. The adaptive protection intelligently adopts suitable settings for the variation of fault current from diversified DG units. Furthermore, the structure of mobile MAS with additional flexibility is capable of adapting the changes of system topology in a short period, e.g. radial/meshed, grid...

  20. Career Adaptability in Adult Vocational Development.

    Science.gov (United States)

    Brizzi, Joan Speight

    Until about two decades ago, researchers considered career maturity primarily in terms of adolescents who struggled with the tasks that, when successfully completed, resulted in a viable career choice. Previously it has been suggested that the term "career adaptability" should replace the term "career maturity" in the study of adult vocational…

  1. Managing for climate change on protected areas: An adaptive management decision making framework.

    Science.gov (United States)

    Tanner-McAllister, Sherri L; Rhodes, Jonathan; Hockings, Marc

    2017-09-18

    Current protected area management is becoming more challenging with advancing climate change and current park management techniques may not be adequate to adapt for effective management into the future. The framework presented here provides an adaptive management decision making process to assist protected area managers with adapting on-park management to climate change. The framework sets out a 4 step process. One, a good understanding of the park's context within climate change. Secondly, a thorough understanding of the park management systems including governance, planning and management systems. Thirdly, a series of management options set out as an accept/prevent change style structure, including a systematic assessment of those options. The adaptive approaches are defined as acceptance of anthropogenic climate change impact and attempt to adapt to a new climatic environment or prevention of change and attempt to maintain current systems under new climatic variations. Last, implementation and monitoring of long term trends in response to ecological responses to management interventions and assessing management effectiveness. The framework addresses many issues currently with park management in dealing with climate change including the considerable amount of research focussing on 'off-reserve' strategies, and threats and stress focused in situ park management. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Development of the adaptive music perception test.

    Science.gov (United States)

    Kirchberger, Martin J; Russo, Frank A

    2015-01-01

    Despite vast amounts of research examining the influence of hearing loss on speech perception, comparatively little is known about its influence on music perception. No standardized test exists to quantify music perception of hearing-impaired (HI) persons in a clinically practical manner. This study presents the Adaptive Music Perception (AMP) test as a tool to assess important aspects of music perception with hearing loss. A computer-driven test was developed to determine the discrimination thresholds of 10 low-level physical dimensions (e.g., duration, level) in the context of perceptual judgments about musical dimensions: meter, harmony, melody, and timbre. In the meter test, the listener is asked to judge whether a tone sequence is duple or triple in meter. The harmony test requires that the listener make judgments about the stability of the chord sequences. In the melody test, the listener must judge whether a comparison melody is the same as a standard melody when presented in transposition and in the context of a chordal accompaniment that serves as a mask. The timbre test requires that the listener determines which of two comparison tones is different in timbre from a standard tone (ABX design). Twenty-one HI participants and 19 normal-hearing (NH) participants were recruited to carry out the music tests. Participants were tested twice on separate occasions to evaluate test-retest reliability. The HI group had significantly higher discrimination thresholds than the NH group in 7 of the 10 low-level physical dimensions: frequency discrimination in the meter test, dissonance and intonation perception in the harmony test, melody-to-chord ratio for both melody types in the melody test, and the perception of brightness and spectral irregularity in the timbre test. Small but significant improvement between test and retest was observed in three dimensions: frequency discrimination (meter test), dissonance (harmony test), and attack length (timbre test). All other

  3. Adaptive Voltage Stability Protection Based on Load Identification Using Phasor Measurement Units

    DEFF Research Database (Denmark)

    Liu, Leo; Bak, Claus Leth; Chen, Zhe

    2011-01-01

    collapse. In this paper, the online load identification using measurement-based approach based on Phasor Measurement Units (PMU) was proposed to evaluate the proximity to voltage instability in order to prevent voltage collapse. In the scenarios of disturbances, the proximity to voltage collapse...... with respect to load characteristics was evaluated. Based on different load characteristics, different control and protection schemes were implemented, i.e. shunt capacitor connection, on-load tap changer blocking and load shedding. The results showed that load-based adaptive voltage control and protection...... scheme based on PMUs is promising, as it prevented the voltage collapse and minimized the load shedding area....

  4. Simulation of adaptive semi-active magnetorheological seat damper for vehicle occupant blast protection

    Science.gov (United States)

    Yoo, Jin-Hyeong; Murugan, Muthuvel; Wereley, Norman M.

    2013-04-01

    This study investigates a lumped-parameter human body model which includes lower leg in seated posture within a quarter-car model for blast injury assessment simulation. To simulate the shock acceleration of the vehicle, mine blast analysis was conducted on a generic land vehicle crew compartment (sand box) structure. For the purpose of simulating human body dynamics with non-linear parameters, a physical model of a lumped-parameter human body within a quarter car model was implemented using multi-body dynamic simulation software. For implementing the control scheme, a skyhook algorithm was made to work with the multi-body dynamic model by running a co-simulation with the control scheme software plug-in. The injury criteria and tolerance levels for the biomechanical effects are discussed for each of the identified vulnerable body regions, such as the relative head displacement and the neck bending moment. The desired objective of this analytical model development is to study the performance of adaptive semi-active magnetorheological damper that can be used for vehicle-occupant protection technology enhancements to the seat design in a mine-resistant military vehicle.

  5. Motivations and Barriers for Policymakers to Developing State Adaptation Plans

    Science.gov (United States)

    Miller, R.; Sylak-Glassman, E.

    2016-12-01

    Current approaches for developing high-quality adaptation plan require significant resources. In recent years, communities have grown to embrace adaptive plans across multiple forms, including adaptive capacity assessments, resilience strategies, and vulnerability assessments. Across the United States, as of this writing, 14 states have established adaptation plans, with another 8 states having begun the process. Given the high resources requirements and increasing interest in the development of adaptation plans, we aim to examine patterns behind the establishment of resilience plans at the state level. We examine demographic, financial, political, and physical characteristics associated with different states in an effort to explore the reasoning behind investing in the development of adaptation plans. This analysis considers quantitative and qualitative factors, including recent elections for political parties, politicians' climate-related statements and campaign promises, demographics, budgets, and regional climate threats. The analysis aims to identify motivations for state leadership taking action to develop adaptation plans. Results from the analysis seek to identify the primary drivers and barriers associated with state-wide resilience planning. These results could inform the design of scientific communication tools or approaches to aid future adaptation responses to climate change.

  6. On the Adaptation of an Agile Information Systems Development Method

    NARCIS (Netherlands)

    Aydin, M.N.; Harmsen, F.; van Slooten, C.; Stegwee, R.A.

    2005-01-01

    Little specific research has been conducted to date on the adaptation of agile information systems development (ISD) methods. This article presents the work practice in dealing with the adaptation of such a method in the ISD department of one of the leading financial institutes in Europe. Two forms

  7. Forestry in times of climatic change. From adaptation to climate protection; Forstwirtschaft in Zeiten des Klimawandels. Von Anpassung bis Klimaschutz

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The notification 30/2010 of the Thuringian State Institute for Forest, Hunting and Fishing (Gotha, Federal Republic of Germany) reports on the forest management in times of the climatic changes. This notification consists of the following contributions: (1) Perception of the climatic change by private forest owners - A social-scientific investigation (Stefanie Rimkus); (2) Fundamentals for the designation of the inventory destination types adapted to climatic change for Thuringia (Nico Frischbier); (3) Recommendations of tree species adapted to climatic change for the forestry practice in Thuringia (Wolfgang Arenhoevel); (4) Development of carbon storage in the state-owned forest Thuringia (Thomas Wutzler); (5) The carbon inventories in copper beech forests (Fagus Sylvatica L.) under the influence of different silvicultural treatment (Martina Mund); (6) Wood products for the climate protection - The state of the art in Thuringia (Ingolf Profft); (7) HABIT-CHANGE - 'Adaptive management of climate-induced changes of habitat diversity in protected areas' (Nico Frischbier); (8) Cultivation experiences of non-indigenous tree species (Wolfgang Ahrenhoevel); (9) Registration of damages of the storm 'Xynthia' in the forestry office Bad Salzungen by means of ANDROMEDA {sup registered} data (Herbert Sagischewski); (10) www.waldundklima.net - The open internet portal on forest, wood and climate (Ingolf Profft).

  8. Developments in the legal protection of IDPs

    Directory of Open Access Journals (Sweden)

    Cordula Droege

    2008-12-01

    Full Text Available Ten years ago the International Committee of the Red Cross(ICRC helped draft the Guiding Principles. How have thePrinciples contributed to improving protection for IDPs?What gaps remain?

  9. Collaborative Learning with Multi-Touch Technology: Developing Adaptive Expertise

    Science.gov (United States)

    Mercier, Emma M.; Higgins, Steven E.

    2013-01-01

    Developing fluency and flexibility in mathematics is a key goal of upper primary schooling, however, while fluency can be developed with practice, designing activities that support the development of flexibility is more difficult. Drawing on concepts of adaptive expertise, we developed a task for a multi-touch classroom, NumberNet, that aimed to…

  10. Development as adaptation: a paradigm for gravitational and space biology

    Science.gov (United States)

    Alberts, Jeffrey R.; Ronca, April E.

    2005-01-01

    Adaptation is a central precept of biology; it provides a framework for identifying functional significance. We equate mammalian development with adaptation, by viewing the developmental sequence as a series of adaptations to a stereotyped sequence of habitats. In this way development is adaptation. The Norway rat is used as a mammalian model, and the sequence of habitats that is used to define its adaptive-developmental sequence is (a) the uterus, (b) the mother's body, (c) the huddle, and (d) the coterie of pups as they gain independence. Then, within this framework and in relation to each of the habitats, we consider problems of organismal responses to altered gravitational forces (micro-g to hyper-g), especially those encountered during space flight and centrifugation. This approach enables a clearer identification of simple "effects" and active "responses" with respect to gravity. It focuses our attention on functional systems and brings to the fore the manner in which experience shapes somatic adaptation. We argue that this basic developmental approach is not only central to basic issues in gravitational biology, but that it provides a natural tool for understanding the underlying processes that are vital to astronaut health and well-being during long duration flights that will involve adaptation to space flight conditions and eventual re-adaptation to Earth's gravity.

  11. Thermal Protection Materials: Development, Characterization and Evaluation

    Science.gov (United States)

    Johnson, Silvia M.

    2012-01-01

    Thermal protection materials and systems (TPS) are used to protect space vehicles from the heat experienced during entry into an atmosphere. The application for these materials is very specialized as are the materials. They must have specific properties to withstand conditions during specific entries. There is no one-size-fits-all TPS as the conditions experienced by a material are very dependent upon the atmosphere, the entry speed, the size and shape of the vehicle, and the location on the vehicle. However, all TPS must be reliable and efficient to ensure mission safety, that is to protect the vehicle while ensuring that payload is maximized. Types of TPS will be reviewed in relation to types of missions and applications. Both reusable and ablative materials will be discussed. Approaches to characterizing and evaluating these materials will be presented. The role of heritage versus new materials will be described.

  12. An Adaptive Privacy Protection Method for Smart Home Environments Using Supervised Learning

    Directory of Open Access Journals (Sweden)

    Jingsha He

    2017-03-01

    Full Text Available In recent years, smart home technologies have started to be widely used, bringing a great deal of convenience to people’s daily lives. At the same time, privacy issues have become particularly prominent. Traditional encryption methods can no longer meet the needs of privacy protection in smart home applications, since attacks can be launched even without the need for access to the cipher. Rather, attacks can be successfully realized through analyzing the frequency of radio signals, as well as the timestamp series, so that the daily activities of the residents in the smart home can be learnt. Such types of attacks can achieve a very high success rate, making them a great threat to users’ privacy. In this paper, we propose an adaptive method based on sample data analysis and supervised learning (SDASL, to hide the patterns of daily routines of residents that would adapt to dynamically changing network loads. Compared to some existing solutions, our proposed method exhibits advantages such as low energy consumption, low latency, strong adaptability, and effective privacy protection.

  13. Development of an intelligent adapter for metered dose inhalers

    Directory of Open Access Journals (Sweden)

    Zhang Mingrong

    2016-01-01

    Full Text Available To better coordinate the interaction of inhalation and aerosol release, an intelligent adapter (IA was developed for metered dose inhalers (MDIs. The adapter included three main units: a signal acquisition device, a micro-control-unit (MCU, and an actuation mechanism. To fully study the effectiveness of the intelligent adapter, an inhalation simulation experiment was done, and two bands of MDI were used for the experiment. The results indicated that, when inhalation, the intelligent adapter can press down the MDI automatically; moreover, this intelligent adapter could achieve an aerosol-release time Tr of 0.4 s for MDI A and 0.60 s for MDI B, which compares very well with the existing pure mechanical systems at 0.8 s and 1.0 s.

  14. Democracy or Intervention? Adapting Orientations to Development

    Science.gov (United States)

    Neame, Charles

    2013-01-01

    Many institutional cultures resist change, and within universities academic developers vary their response to such resistance, depending on the type of change, the institution and their own characteristic styles, working preferences and strategic judgements. Variables influencing the successful introduction of innovation in academic practice…

  15. Priming adaptation pathways through adaptive co-management: Design and evaluation for developing countries

    Directory of Open Access Journals (Sweden)

    J.R.A. Butler

    2016-01-01

    Full Text Available Mainstreaming climate change and future uncertainty into rural development planning in developing countries is a pressing challenge. By taking a complex systems approach to decision-making, the adaptation pathways construct provides useful principles. However, there are no examples of how to operationalise adaptation pathways in developing countries, or how to evaluate the process. This paper describes a 4 year governance experiment in Nusa Tenggara Barat Province, Indonesia, which applied adaptive co-management (ACM as a governance approach to ‘prime’ a transformation to adaptation pathways-based development planning. The project’s Theory of Change (ToC consisted of three causally-linked phases which mirrored the evolutionary stages of ACM: priming stakeholders, enabling policies and programs, and implementing adaptation. The first phase established a trans-disciplinary research team to act as facilitators and brokers, a multi-stakeholder planning process demonstrating adaptation pathways practice, and trialling of ‘no regrets’ adaptation strategies in case study sub-districts. A participatory evaluation method was designed to test the ToC’s assumptions and measure ACM outcomes. Stakeholder interviews at the project’s closure indicated that through ACM, stakeholders had been successfully primed: leaders emerged, trust, cross-scale social networks and knowledge integration grew, communities were empowered, and innovative adaptation strategies were developed and tested. However, there was limited evidence of institutional change to existing planning processes. This was attributed to the absence of policy windows due to ineffective and insufficient time for political engagement, and the fluid institutional environment caused by a national decentralisation policy. To enhance the priming of adaptation pathways into development planning under these conditions, three recommendations are made: (1 provide long term support for emergent

  16. Does bilirubin protect against developing diabetes mellitus?

    Science.gov (United States)

    Breimer, Lars H; Mikhailidis, Dimitri P

    2016-01-01

    After 25 years of evaluating bilirubin as a possible protective agent in neonatal and cardiovascular disease, interest has moved on to a exploring a possible protective role in diabetes mellitus (DM). This review finds conflicting prospective data for a protective relationship though there are retrospective, case-controlled data, that can only show association, which is not causality. Only prospective studies can show causality. Also, it would appear that the underlying biochemical assumptions do not readily translate from the animal to the human setting. Given that many factors impact on circulating bilirubin levels, it is not surprising that a clear-cut answer is not available; the jury is still out. Any relationship between DM and bilirubin might relate to intermediates in bilirubin metabolism, including relationships involving the genes for the enzymes participating in those steps. Nevertheless, the pursuit of bilirubin in disease causation is opening new avenues for research and if it is established that serum bilirubin can predict risks, much will have been achieved. The answer may have to come from molecular genetic analyses.

  17. Development and adaptation of protein digestion.

    Science.gov (United States)

    Austic, R E

    1985-05-01

    Protein digestion is a complex process in which most aspects have a developmental pattern of activity. Gastric pH and intestinal peptide and amino acid transport as well as the activities of pepsinogen, trypsin, chymotrypsin, enterokinase and intestinal dipeptidases vary during development. No one species has been assessed for all these aspects and it is not possible to present an integrated developmental view of protein digestion. The following developmental changes, however, have been observed. Gastric pH declines, and peptic and pancreatic proteases exhibit increasing activity in pigs and rats after birth. The increase in pigs is gradual over several weeks starting at birth, whereas the increases in the rat begin at 2 wk, just prior to the time of weaning. The activities of dipeptidases in the rat and pig, peptide transport systems in the guinea pig and rabbit and amino acid transport systems in the rat, rabbit, guinea pig and chicken, however, appear (with few exceptions) to be active in the small intestine at the time of birth. Frequently, these activities peak in the neonate and decline during the postnatal period. In the rat, dietary protein tends to increase the activities of pancreatic proteases and intestinal peptidases and to increase the rate of uptake of amino acids by the intestinal epithelium. Individual dietary amino acids also influence amino acid transport systems. The data indicate that most processes in protein digestion undergo marked changes during prenatal and postnatal development and are influenced by the level of feeding and composition of the diet.

  18. Career Development and Older Workers: Study Evaluating Adaptability in Older Workers Using Hall's Model

    Science.gov (United States)

    Strate, Merwyn L.; Torraco, Richard J.

    2005-01-01

    This qualitative case study described the development of adaptive competence in older workers using a Model of Adaptability and Adaptation developed by Dr. Douglas T. Hall (2002). Few studies have focused on the development of adaptability in workers when faced with change and no studies have focused on the development of adaptability in older…

  19. Extent and evaluation of protection in developing countries

    NARCIS (Netherlands)

    J. Kol (Jacob)

    1995-01-01

    textabstractTariff protection and nontariff barriers are higher in developing countries than in industrial nations. The tendency of protection to decline with a higher level of development can be explained by the role of import taxes in government revenue, by export pessimism, and by differential tr

  20. Developing biomedical devices design, innovation and protection

    CERN Document Server

    Andreoni, Giuseppe; Colombo, Barbara

    2013-01-01

    During the past two decades incredible progress has been achieved in the instruments and devices used in the biomedical field. This progress stems from continuous scientific research that has taken advantage of many findings and advances in technology made available by universities and industry. Innovation is the key word, and in this context legal protection and intellectual property rights (IPR) are of crucial importance. This book provides students and practitioners with the fundamentals for designing biomedical devices and explains basic design principles. Furthermore, as an aid to the dev

  1. Climate change adaptation in Ethiopia: to what extent does social protection influence livelihood diversification?

    DEFF Research Database (Denmark)

    Weldegebriel, Zerihun; Prowse, Martin Philip

    2013-01-01

    Social-protection programmes like the Productive Safety-Net Programme (PSNP) in Ethiopia can play a positive role in promoting livelihoods and enhancing risk management. This article uses propensity score matching to estimate its effect on income diversification. The results suggest that receivin...... in a positive manner for climate adaptation. The article concludes by arguing for the promotion of positive forms of income diversification and the further investigation of the PSNP’s influence on autonomous adaptation strategies.......Social-protection programmes like the Productive Safety-Net Programme (PSNP) in Ethiopia can play a positive role in promoting livelihoods and enhancing risk management. This article uses propensity score matching to estimate its effect on income diversification. The results suggest that receiving...... transfers from the PSNP, on average, did not increase farm or non-farm income but significantly increases natural-resource extraction (one component of off-farm income). While these results should be treated with caution, they suggest that the PSNP may not be helping smallholders diversify income sources...

  2. Development of Adaptive Mobile Learning (AML on Information System Courses

    Directory of Open Access Journals (Sweden)

    I Made Agus Wirawan

    2015-12-01

    Full Text Available In general, the learning process is done conventionally, where the learning process is done face to face between teachers with learners in the classroom. Teachers have a very important role in determining the quantity and quality of the implementation study. Therefore, teachers must think and plan carefully to improve learning opportunities for learners and improve the quality of teaching. Along with the development of mobile technology and communication is rapidly increasing, enabling the learning process is not only done in the classroom, but can be done anywhere and anytime. Based on the analysis of the results of observations in the class conducted by a researcher and as a teacher in the learning courses of Information Systems, found some obstacles encountered during the learning process This research is to develop an Adaptive Mobile Learning on Information Systems courses. The method used in this research is the development of research methods (research and development, which selected the design development using System Development Life Cycle model. Adaptive Mobile Learning will be validated and tested through three phases of testing are: (1 Product technical test as a software. (2 Testing of the product as a medium of learning, through expert review by a media expert, (3 Field test to evaluate the response of the students that learned Adaptive Mobile Learning. The results show that Adaptive Mobile Learning software is can present the material in the course of Information Systems. Media Adaptive Mobile Learning can be used as an alternative medium (supplement of learning Information Systems courses. The response of students to the development and use of software for Adaptive Mobile Learning Information Systems courses is likely to very positive, which is at 67.7% very positive and 32.3% is positive.

  3. Adaptive planning : Generating conditions for urban adaptability.Lessons from Dutch organic development strategies

    NARCIS (Netherlands)

    Rauws, Ward; de Roo, Gert

    2016-01-01

    The development of cities includes a wide variety of uncertainties which challenge spatial planners and decision makers. In response, planning approaches which move away from the ambition to achieve predefined outcomes are being explored in the literature. One of them is an adaptive approach to

  4. The value and adaptation of plant uptake models in international trade of produce treated with crop protection products

    DEFF Research Database (Denmark)

    Kennedy, C.; Anderson, J.; Snyder, N.;

    2010-01-01

    residues based on limited data sets affords business value by enabling informed product development decisions about the likelihood for MRL compliance for varied product use scenarios. Predicted residues can additionally support the design and conduct of time-constrained interdependent studies required......Crop Protection Product (CPP) national registrations and/or international trade require magnitude and decline of residue data for treated produce. These data are used to assess human dietary risk and establish legal limits (Maximum Residue Limits, MRLs) for traded produce. The ability to predict...... for product registrations. While advances in predicting residues for the case of foliar applications of CPPs have been achieved, predictions for the case of soil applications of CPPs provide additional challenge. The adaptation of a newly developed dynamic model to CPP product use scenarios will be explored...

  5. Develop hydroenergy resources and protect earth environment

    Institute of Scientific and Technical Information of China (English)

    Lu Youmei

    2009-01-01

    Energy is a driving force behind the progress of human civilization. Mainly depend on the current human soci-ety of non-renewable fossil energy sources, such as coal and oil, its increasing demand. Gradually reduce the reserves, the contradiction between supply and demand becoming increasingly prominent. With the process of human history has moved forward with the depletion of fossil energy will eventually be unable to sustainable use. The total hydropower re-sources are limited, but it is renewable, clean energy, its energy is infinite. Therefore, the full use of limited water re-sources and slow down the depletion of fossil energy process, is to improve and protect the earth's ecology and environ-ment, one of the most realistic measures.

  6. Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge.

    Directory of Open Access Journals (Sweden)

    Shailbala Singh

    Full Text Available Sublingual route offers a safer and more practical approach for delivering vaccines relative to other systemic and mucosal immunization strategies. Here we present evidence demonstrating protection against ovalbumin expressing B16 (B16-OVA metastatic melanoma lung tumor formation by sublingual vaccination with the model tumor antigen OVA plus synthetic glycolipid alpha-galactosylceramide (aGalCer for harnessing the adjuvant potential of natural killer T (NKT cells, which effectively bridge innate and adaptive arms of the immune system. The protective efficacy of immunization with OVA plus aGalCer was antigen-specific as immunized mice challenged with parental B16 tumors lacking OVA expression were not protected. Multiple sublingual immunizations in the presence, but not in the absence of aGalCer, resulted in repeated activation of NKT cells in the draining lymph nodes, spleens, and lungs of immunized animals concurrent with progressively increasing OVA-specific CD8+ T cell responses as well as serum IgG and vaginal IgA levels. Furthermore, sublingual administration of the antigen only in the presence of the aGalCer adjuvant effectively boosted the OVA-specific immune responses. These results support potential clinical utility of sublingual route of vaccination with aGalCer-for prevention of pulmonary metastases.

  7. Sublingual vaccination induces mucosal and systemic adaptive immunity for protection against lung tumor challenge.

    Science.gov (United States)

    Singh, Shailbala; Yang, Guojun; Schluns, Kimberly S; Anthony, Scott M; Sastry, K Jagannadha

    2014-01-01

    Sublingual route offers a safer and more practical approach for delivering vaccines relative to other systemic and mucosal immunization strategies. Here we present evidence demonstrating protection against ovalbumin expressing B16 (B16-OVA) metastatic melanoma lung tumor formation by sublingual vaccination with the model tumor antigen OVA plus synthetic glycolipid alpha-galactosylceramide (aGalCer) for harnessing the adjuvant potential of natural killer T (NKT) cells, which effectively bridge innate and adaptive arms of the immune system. The protective efficacy of immunization with OVA plus aGalCer was antigen-specific as immunized mice challenged with parental B16 tumors lacking OVA expression were not protected. Multiple sublingual immunizations in the presence, but not in the absence of aGalCer, resulted in repeated activation of NKT cells in the draining lymph nodes, spleens, and lungs of immunized animals concurrent with progressively increasing OVA-specific CD8+ T cell responses as well as serum IgG and vaginal IgA levels. Furthermore, sublingual administration of the antigen only in the presence of the aGalCer adjuvant effectively boosted the OVA-specific immune responses. These results support potential clinical utility of sublingual route of vaccination with aGalCer-for prevention of pulmonary metastases.

  8. Applying Adapted Big Five Teamwork Theory to Agile Software Development

    OpenAIRE

    Strode, Diane

    2016-01-01

    Teamwork is a central tenet of agile software development and various teamwork theories partially explain teamwork in that context. Big Five teamwork theory is one of the most influential teamwork theories, but prior research shows that the team leadership concept in this theory it is not applicable to agile software development. This paper applies an adapted form of Big Five teamwork theory to cases of agile software development. Three independent cases were drawn from a single organisation....

  9. ECONOMIC DEVELOPMENT AND ENVIRONMENT PROTECTION RELATIONSHIP

    Directory of Open Access Journals (Sweden)

    POPESCU CONSTANTIN

    2012-05-01

    Full Text Available The social and economical development must be approached in such a way that it minimizes the effects of the economic activity over the deterioration of resources and to discourage waste. The pollution control depends on humans’ ability to understand the seriousness of the ecological lack of balance.The sustainable lasting development, being a long term economical development, is possible by efficiently using the economical instruments (cost, profit; the political, juridical and social ones, which utter signals for the economic agents, so that they can become aware of the limited character of natural resources and of the damage caused to the environment.

  10. Development of an Active Topical Skin Protectant (aTSP)

    Science.gov (United States)

    2016-02-01

    topical protectant to vulnerable skin surfaces prior to entry into a chemical combat arena was proposed as a protective measure against percutaneous...candidate formulations. The initial analytical method developed for evaluating the effectiveness of TSPs against penetration by HD used Fourier...Several evaluation techniques, including bioengineering analytical technologies, were used to evaluate skin damage under several protocols. Methods

  11. An Adaptive Design Methodology for Reduction of Product Development Risk

    CERN Document Server

    Pakala, Hara Gopal Mani; Kvsvn, Dr Raju; Khan, Dr Ibrahim; 10.5121/ijasuc.2011.2303

    2011-01-01

    Embedded systems interaction with environment inherently complicates understanding of requirements and their correct implementation. However, product uncertainty is highest during early stages of development. Design verification is an essential step in the development of any system, especially for Embedded System. This paper introduces a novel adaptive design methodology, which incorporates step-wise prototyping and verification. With each adaptive step product-realization level is enhanced while decreasing the level of product uncertainty, thereby reducing the overall costs. The back-bone of this frame-work is the development of Domain Specific Operational (DOP) Model and the associated Verification Instrumentation for Test and Evaluation, developed based on the DOP model. Together they generate functionally valid test-sequence for carrying out prototype evaluation. With the help of a case study 'Multimode Detection Subsystem' the application of this method is sketched. The design methodologies can be compar...

  12. Roles of dental development and adaptation in rodent evolution.

    Science.gov (United States)

    Rodrigues, Helder Gomes; Renaud, Sabrina; Charles, Cyril; Le Poul, Yann; Solé, Floréal; Aguilar, Jean-Pierre; Michaux, Jacques; Tafforeau, Paul; Headon, Denis; Jernvall, Jukka; Viriot, Laurent

    2013-01-01

    In paleontology, many changes affecting morphology, such as tooth shape in mammals, are interpreted as ecological adaptations that reflect important selective events. Despite continuing studies, the identification of the genetic bases and key ecological drivers of specific mammalian dental morphologies remains elusive. Here we focus on the genetic and functional bases of stephanodonty, a pattern characterized by longitudinal crests on molars that arose in parallel during the diversification of murine rodents. We find that overexpression of Eda or Edar is sufficient to produce the longitudinal crests defining stephanodonty in transgenic laboratory mice. Whereas our dental microwear analyses show that stephanodonty likely represents an adaptation to highly fibrous diet, the initial and parallel appearance of stephanodonty may have been facilitated by developmental processes, without being necessarily under positive selection. This study demonstrates how combining development and function can help to evaluate adaptive scenarios in the evolution of new morphologies.

  13. [Development of sociopsychological adaptation of schoolchildren and vocational school pupils].

    Science.gov (United States)

    Goncharov, G A; Nadezhdin, D S

    2009-01-01

    The purpose of this study was to comparatively analyze the influence of family factors on social and psychological adaptation and achievement motivation in pupils from general education schools and in their coevals from vocational educational schools (VES). An experimental study was conducted in 10th-form pupils from a number of Moscow schools and persons of the same age who were one-year course pupils from a Moscow VES. A total of 242 pupils, including 130 schoolchildren and 112 one-year course pupils from the VES, were examined. The social and psychological adaptation questionnaire developed by K. Rodgers and R. Diamond was used to estimate achievement motivation by the Mehrabian test. The performed study confirmed the negative impact of poor family relations on pupils' sociological and psychological adaptation independently of the type of a general educational establishment. The high maternal educational level had a good effect on the adaptability of schoolchildren, that of boys in particular, whereas the paternal educational status is of the same value to VES pupils. Family relations and maternal and paternal education levels significantly affect the formation of achievement motive in pupils and their social and psychological adaptation as a whole.

  14. Offshore Oil Development versus Environmental Protection

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Offshore petroleum development is an expensive and high-risk operation that applies advanced science and technology. The Bohai Bay oil spill has resulted in calls for changes in the relationship between China and the foreign oil companies that enable the search for resources. Amid the criticism heaped on ConocoPhillips Co. - the United States-based energy conglomerate whose operations spilled more than 700 barrels of oil into the waters of China's Bohai Bay in June, the nation's industrial experts are clamoring for a review of the policies for oil and gas exploration with foreign oil companies in China.

  15. Recent Developments in Smart Adaptive Structures for Solar Sailcraft

    Science.gov (United States)

    Whorton, M. S.; Kim, Y. K.; Oakley, J.; Adetona, O.; Keel, L. H.

    2007-01-01

    The "Smart Adaptive Structures for Solar Sailcraft" development activity at MSFC has investigated issues associated with understanding how to model and scale the subsystem and multi-body system dynamics of a gossamer solar sailcraft with the objective of designing sailcraft attitude control systems. This research and development activity addressed three key tasks that leveraged existing facilities and core competencies of MSFC to investigate dynamics and control issues of solar sails. Key aspects of this effort included modeling and testing of a 30 m deployable boom; modeling of the multi-body system dynamics of a gossamer sailcraft; investigation of control-structures interaction for gossamer sailcraft; and development and experimental demonstration of adaptive control technologies to mitigate control-structures interaction.

  16. Implementing WAI Authoring Tool Accessibility Guidelines in Developing Adaptive Elearning

    Directory of Open Access Journals (Sweden)

    Mahieddine Djoudi

    2012-09-01

    Full Text Available Adaptive learning technology allows for the development of more personalized online learning experiences with materials that adapt to student performance and skill level. The term “adaptive” is also used to describe Assistive Technologies that allow the usability of online based courses for learners with disabilities and special needs. Authoring tools can enable, encourage, and assist authors in the creation of elearning content. Because most of the content of the Web based adaptive learning is created using authoring tools, they may be accessible to authors regardless of disability and they may support and encourage the authors in creating accessible elearning content. This paper presents an authoring tool designed for developing accessible adaptive elearning. The authoring tool, dedicated to Algerian universities, is designed to satisfy the W3C/WAI Authoring Tool Accessibility Guidelines (ATAG, and to allow collaboration functionalities among teachers where building elearning courses. After presenting the W3C/WAI accessibility guidelines, the collaborative authoring tool is outlined.

  17. Development and Climate Change: A Mainstreaming Approach for Assessing Economic, Social, and Environmental Impacts of Adaptation Measures

    DEFF Research Database (Denmark)

    Halsnæs, Kirsten; Trærup, Sara Lærke Meltofte

    2009-01-01

    how development policy indicators in practice can be used to assess climate change impacts and adaptation measures based on three case studies, namely a road project in flood prone areas of Mozambique, rainwater harvesting in the agricultural sector in Tanzania and malaria protection in Tanzania...

  18. Physical protection evaluation methodology program development and application

    Energy Technology Data Exchange (ETDEWEB)

    Seo, Janghoon; Yoo, Hosik [Korea Institute of Nuclear Non-proliferation and Control, Daejeon (Korea, Republic of)

    2015-10-15

    It is essential to develop a reliable physical protection evaluation methodology for applying physical protection concept to the design stage. The methodology can be used to assess weak points and improve performance not only for the design stage but also for nuclear facilities in operation. Analyzing physical protection property of nuclear facilities is not a trivial work since there are many interconnected factors affecting overall performance. Therefore several international projects have been organized to develop a systematic physical protection evaluation methodology. INPRO (The International Project on Innovative Nuclear Reactors and Fuel Cycles) and GIF PRPP (Generation IV International Forum Proliferation Resistance and Physical Protection) methodology are among the most well-known evaluation methodologies. INPRO adopts a checklist type of questionnaire and has a strong point in analyzing overall characteristic of facilities in a qualitative way. COMPRE program has been developed to help general users apply COMPRE methodology to nuclear facilities. In this work, COMPRE program development and a case study of the hypothetical nuclear facility are presented. The development of COMPRE program and a case study for hypothetic facility is presented in this work. The case study shows that COMPRE PP methodology can be a useful tool to assess the overall physical protection performance of nuclear facilities. To obtain meaningful results from COMPRE PP methodology, detailed information and comprehensive analysis are required. Especially, it is not trivial to calculate reliable values for PPSE (Physical Protection System Effectiveness) and C (Consequence), while it is relatively straightforward to evaluate LI (Legislative and Institutional framework), MC (Material Control) and HR (Human Resources). To obtain a reliable PPSE value, comprehensive information about physical protection system, vital area analysis and realistic threat scenario assessment are required. Like

  19. Cooperative drought adaptation: Integrating infrastructure development, conservation, and water transfers into adaptive policy pathways

    Science.gov (United States)

    Zeff, Harrison B.; Herman, Jonathan D.; Reed, Patrick M.; Characklis, Gregory W.

    2016-09-01

    A considerable fraction of urban water supply capacity serves primarily as a hedge against drought. Water utilities can reduce their dependence on firm capacity and forestall the development of new supplies using short-term drought management actions, such as conservation and transfers. Nevertheless, new supplies will often be needed, especially as demands rise due to population growth and economic development. Planning decisions regarding when and how to integrate new supply projects are fundamentally shaped by the way in which short-term adaptive drought management strategies are employed. To date, the challenges posed by long-term infrastructure sequencing and adaptive short-term drought management are treated independently, neglecting important feedbacks between planning and management actions. This work contributes a risk-based framework that uses continuously updating risk-of-failure (ROF) triggers to capture the feedbacks between short-term drought management actions (e.g., conservation and water transfers) and the selection and sequencing of a set of regional supply infrastructure options over the long term. Probabilistic regional water supply pathways are discovered for four water utilities in the "Research Triangle" region of North Carolina. Furthermore, this study distinguishes the status-quo planning path of independent action (encompassing utility-specific conservation and new supply infrastructure only) from two cooperative formulations: "weak" cooperation, which combines utility-specific conservation and infrastructure development with regional transfers, and "strong" cooperation, which also includes jointly developed regional infrastructure to support transfers. Results suggest that strong cooperation aids utilities in meeting their individual objectives at substantially lower costs and with less overall development. These benefits demonstrate how an adaptive, rule-based decision framework can coordinate integrated solutions that would not be

  20. Developing a Climate Change Boundary Organization: the Montana Adaptation Exchange

    Science.gov (United States)

    Whitlock, C. L.; Brooks, S.; Armstrong, T.; Bryan, B.

    2016-12-01

    Small-population large-area states like Montana are often challenged by a need to offer timely and relevant climate-change information that addresses diverse and widely dispersed stakeholder groups. In Montana, filling the gap between science and various types of decision-makers has motivated development of the first Montana Climate Assessment (MCA1), to be released in 2017 with a focus on climate-change impacts for agricultural, water and forestry sectors. To sustain and build on the MCA1 effort, we are also in the process of creating a Boundary Organization (defined by the National Academy of Sciences) called the Montana Adaptation Exchange (the Exchange); this entity will facilitate the flow of information across the boundaries between science, knowledge and implementation. In Montana, the Exchange brings scientists and practitioners together to seek solutions related to climate-change adaptation and other pressing environmental and social-economic challenges. The Montana Adaptation Exchange (1) is a collaborative partnership of members from the science and practitioner communities under a shared governance and participatory model; (2) presents research that has been vetted by the scientific community at large and represents the current state of knowledge; (3) allows for revision and expansion of assessments like the MCA; (4) communicates relevant, often technical, research and findings to a wide variety of resource managers and other stakeholders; (5) develops and maintains an extensive online database that organizes, regularly updates, and makes research data products readily available; and (6) offers an online portal and expert network of affiliated researchers and climate adaptation specialists to provide effective customer support. Boundary organizations, such as the Montana Adaptation Exchange, offer a scalable path to effectively move from "science to knowledge to action" while also allowing stakeholder needs to help inform research agendas.

  1. Development of Climate Change Adaptation Platform using Spatial Information

    Science.gov (United States)

    Lee, J.; Oh, K. Y.; Lee, M. J.; Han, W. J.

    2014-12-01

    Climate change adaptation has attracted growing attention with the recent extreme weather conditions that affect people around the world. More and more countries, including the Republic of Korea, have begun to hatch adaptation plan to resolve these matters of great concern. They all, meanwhile, have mentioned that it should come first to integrate climate information in all analysed areas. That's because climate information is not independently made through one source; that is to say, the climate information is connected one another in a complicated way. That is the reason why we have to promote integrated climate change adaptation platform before setting up climate change adaptation plan. Therefore, the large-scaled project has been actively launched and worked on. To date, we researched 620 literatures and interviewed 51 government organizations. Based on the results of the researches and interviews, we obtained 2,725 impacts about vulnerability assessment information such as Monitoring and Forecasting, Health, Disaster, Agriculture, Forest, Water Management, Ecosystem, Ocean/Fisheries, Industry/Energy. Among 2,725 impacts, 995 impacts are made into a database until now. This database is made up 3 sub categories like Climate-Exposure, Sensitivity, Adaptive capacity, presented by IPCC. Based on the constructed database, vulnerability assessments were carried out in order to evaluate climate change capacity of local governments all over the country. These assessments were conducted by using web-based vulnerability assessment tool which was newly developed through this project. These results have shown that, metropolitan areas like Seoul, Pusan, Inchon, and so on have high risks more than twice than rural areas. Acknowledgements: The authors appreciate the support that this study has received from "Development of integrated model for climate change impact and vulnerability assessment and strengthening the framework for model implementation ", an initiative of the

  2. General Survey for Lightning Protection Standards Development in China

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    @@ The introduction of IEC/TC81 Thunderstorms are natural weather phenomena and there are no devices or methods capable of preventing lightning discharges. Lightning flashes striking structures or services entering the structures, or striking earth nearby are hazardous to people, to the structures themselves, their contents and installations, as well as to services.Hence lightning protection is very important for national economic development. The international trade in lightning protection measures integrat ed in plants or buildings is of increasing importance:more than 500 million USD, world wide are estimated today; consequent loss, where protection measures are not provided, is some order of magnitude higher.The number of countries where lightning protection is required either by law or by insurance companies is growing. Some countries have conflicting national rules and many developing countries do not have the relevant international standards, making the need for such standards all the more urgent.

  3. Can Protection Motivation Theory explain farmers'adaptation to Climate change/variability decision making in the Gambia?

    Science.gov (United States)

    Bagagnan, A. R.

    2016-12-01

    In the Gambia, Changes in the climate pattern has affected and continue to affect the agriculture sector and therefore calling for effective adaptation policies. The present study aimed to explain farmers' adoption of climate change adaptation measure through the protection motivation theory in The Central River Region of The Gambia. Primary data were collected in all the eight communities of the study area. A transect walk was conducted first followed by a survey with 283 informants. The perception variables were referring to the past 20 years while the stated implementation was addressing the current adaptation practices. Results showed that on one hand, most of the perception variables such as severity, ability to withstand, and internal barriers are significantly correlated to protection motivation and on the other hand Protection motivation and stated implementation for water conservation technique are strongly correlated. Structural Equation Modeling confirms the mediation role of Protection motivation between Farmers stated implementation and their perception of climate variability. Decrease in soil water storage capacity, degradation of the quality of soil surface structure, decrease of the length of the growing season are factors that motivate farmers to implement an adaptation measure. Cost of the implementation and farmers' vulnerability are factors that prevent farmers to implement an adaptation measure. The cost of the implementation is the main barrier to farmers `protection motivation. Therefore the study suggested that farmers' awareness about climate change/variability should be increased through farmers' field school and awareness campaigns, farmers' resilience should be improved and adaptation measures should be made accessible to farmers through loans facilities and subsidizes application.

  4. Adapting the innovation systems approach to agricultural development in Vietnam

    DEFF Research Database (Denmark)

    Friederichsen, Rupert; Thai, Thi Minh; Neef, Andreas

    2013-01-01

    Competing models of innovation informing agricultural extension, such as transfer of technology, participatory extension and technology development, and innovation systems have been proposed over the last decades. These approaches are often presented as antagonistic or even mutually exclusive...... is broadly appropriate for analyzing the Vietnamese case, but that the IS approach in the contemporary Vietnamese context requires adaptation for taking into account the blurred line between private and state sectors, and recognizing the hegemonic position of state-based networks. Improving extensionists...

  5. Software development for bistable module of SMART plant protection system

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. H.; Park, H. S.; Jeo, C. W. [Samchang Enterprise Co., Ltd., Taejon (Korea, Republic of); Lee, J. G.; Park, H. Y.; Koo, I. S. [KAERI, Taejon (Korea, Republic of)

    2003-10-01

    Digitalized PPS(Plant Protection System) is going on development for SMART. The PPS consists of two different types of CPUs and DSP boards for the each functional processor modules of PPS. Software for the system has been progressed with teamwork of CASE TOOL to develop the reliable software. In this paper, we propose the software development method and show the examples for Bistable module through the functional analysis and the development of Structure Chart and M-Spec.

  6. Development of protected area system of the Komi Republic

    Directory of Open Access Journals (Sweden)

    Tatyana Vyacheslavovna Tikhonova

    2013-09-01

    Full Text Available In this article, the damages for biodiversity on the Republic of Komi Protected Areas are outlined. World experience of organizing Protected Areas is represented. The central management tasks into categories of domestic Protected areas are shown. Analysis of prevailing categories of these objects functioning by continents is carried out. The main resources of financing are listed including state investments, various payments, taxes and charitable and grant incomes. In the result of the economic evaluation potential recipients of benefits from the usage of bioresources and ecosystem services on model objects are defined, including the world community, local inhabitants and tourists. Territories that possess reserve for increased usage of its resources and services are represented. The Russian experience of attracting investment, using of economic potential and cultural traditions, development of recreation, tourism and tourism industry and revival of native craft is shown. Actual and perspective objects of tourism and recreation on the territory of Protected Areas are represented

  7. Developing and protecting intellectual property in virtual projects : Trade secret protection in Telecommunications

    OpenAIRE

    Gonzalez Ruiz, Diego Hernan

    2012-01-01

    This thesis is intended to develop a comprehensive understanding of how trade secrets can be used as a means to protect knowledge developed through projects conducted in the telecommunications sector. At the same time, the study explores which mechanisms should be employed to regulate access and utilization of trade secrets when their disclosure is inevitable to accomplish project requirements. Telecommunication firms are large and globally distributed organizations whose business operations ...

  8. Developing Culture-Adaptive Competency Through Experiences with Expressive Avatars

    Science.gov (United States)

    Silverglate, Daniel S.; Sims, Edward M.; Glover, Gerald; Friedman, Harris

    2012-01-01

    Modern Warfighters often find themselves in a variety of non-combat roles such as negotiator, peacekeeper, reconstruction, and disaster relief. They are expected to perform these roles within a culture alien to their own. Each individual they encounter brings their own set of values to the interaction that must be understood and reconciled. To navigate the human terrain of these complex interactions, the Warfighter must not only consider the specifics of the target culture, but also identify the stakeholders, recognize the influencing cultural dimensions, and adapt to the situation to achieve the best possible outcome. Vcom3D is using game-based scenarios to develop culturally adaptive competency. The avatars that represent the stakeholders must be able to portray culturally accurate behavior, display complex emotion, and communicate through verbal and non-verbal cues. This paper will discuss the use of emerging game technologies to better simulate human behavior in cross-cultural dilemmas. Nomenclature: culture, adaptive, values, cultural values dimensions, dilemmas, virtual humans, non-verbal communications

  9. IAEA activities and new developments in optimization of radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Na, Seong H. [IAEA, Vienna (Austria)

    1999-07-01

    Providing effective support for occupational radiation protection to IAEA Member States is an increasingly more demanding task. The Agency is approaching the challenge through implementation of a multicomponent programme based on the development of comprehensive guidance presented in the Safety Standards document series. These are augmented by specific technical recommendations published in the newly established Safety Reports series. Direct national and regional assistance, based on the recommendations and information presented in the IAEA documents is provided through an active Technical Cooperation programme. Finally, specific technical issues, including optimization of radiation protection, are addressed through occupational protection programmes. Further information on IAEA radiation protection programmes can be found on the Web site at: www.iaea.org/ns/rasanet/. Optimization of protection is an idea of very broad application. It can be used at all levels from simple day to day decisions to major analysis of different types of plant design and it should be applied in all areas of radiation protection; including medical diagnostic uses of radiation, control of exposure to natural radiation and the control of exposures in general industry as well as in the perhaps more publicized area of the nuclear power industry. The optimization idea should also in principle apply to procedures designed to prevent or mitigate the consequences of accidents or incidents that could lead to radiation exposure. In this paper the focus is on the principle of optimization stated in the BSS. And it presents the key concepts of optimization of radiation protection and main indicators of dose reduction, which have been collected from existing reports including drafts under developing. The effect of applying the optimization procedure for maintenance operations are also introduced as well as the main causes to prolong exposure time. (author). 3 tabs., 1 fig.

  10. Development of a Piezoelectric Adaptive Mirror for Laser Beam Control

    CSIR Research Space (South Africa)

    Long, CS

    2008-06-01

    Full Text Available stream_source_info Long1_2008.pdf.txt stream_content_type text/plain stream_size 15110 Content-Encoding UTF-8 stream_name Long1_2008.pdf.txt Content-Type text/plain; charset=UTF-8 ACTUATOR 2008, 11th International... Conference on New Actuators, Bremen, Germany, 9 – 11 June 2008584 P 17 Development of a Piezoelectric Adaptive Mirror for Laser Beam Control Craig S. Long1, Philip W. Loveday1 and Andrew Forbes1,2 1Council for Scientific and Industrial Research, PO...

  11. Harness: Development of a multifunctional protective ship bulkhead

    NARCIS (Netherlands)

    Wal, R. van der; Meuers, R.J.C.

    2016-01-01

    HARNESS is a joint project between governments, industry and TNO with the objective to develop a multifunctional protective bulkhead for application on naval vessels. The multifunctional bulkhead aims at increasing the resilience of naval vessels, reduce damage and repair time and provide a safer en

  12. Research and development in radiological protection; Investigacion y desarrollo en proteccion radiologica

    Energy Technology Data Exchange (ETDEWEB)

    Butragueno, J. L.; Villota, C.; Gutierrez, C.; Rodriguez, A.

    2004-07-01

    The objective of Radiological Protection is to gurantee that neither people, be they workers or members of the public, or the environment are exposed to radiological risks considered by society to be unacceptable. Among the various resources available to meet this objective is Research and Development (R and D), which is carried out in three areas: I. Radiological protection of persons: (a) knowledge of the biological effects of radiations, in order to determine the relationship that exists between radiation exposure dose and its effects on health; (b) the development of new personal dosimetry techniques in order to adapt to new situations, instrumental techniques and information managmenet technologies allowing for better assessment of exposure dose; and (c) development of the principle of radiological protection optimisation (ALARA), which has been set up internationally as the fundamental principle on which radiological protection interventions are based. II. Assessment of environmental radiological impact, the objective of which is to assess the nature and magnitude of situations of exposure to ionising radiations as a result of the controlled or uncontrolled release of radioactive material to the environment, and III.Reduction of the radiological impact of radioactive wastes, the objective of which is to develop radioactive material and waste management techniques suitable for each situation, in order to reduce the risks assocaited with their definitive managmenet or thier release to the environment. Briefly desribed below are the strategic lines of R and D of the CSN, the Electricity Industry, Ciemat and Enresa in the aforementioned areas. (Author)

  13. Economic valuation of climate change adaptation in developing countries.

    Science.gov (United States)

    Stage, Jesper

    2010-01-01

    This paper reviews the literature on the economics of climate change adaptation in developing countries, and identifies three key points for consideration in future studies. One key point is that all development policy should be formulated using forecasts from climate science as a baseline. When this is not done, there is risk that a false status quo without climate change is seen as an implicit baseline. Another key point is that authors must be clearer about their behavioral assumptions: Many studies either (problematically) assume profit maximization on the side of farm households, or do not specify behavioral assumptions at all. A third important point is that the allocation of rights is crucial for the results; if households have a right to maintain their current livelihoods, the costs of climate change in developing countries are considerably greater than traditional willingness-to-pay studies would indicate. Thus, costs and benefits of climate change adaptation cannot be analyzed using economic aspects only; climate science, behavioral science, and legal and moral aspects have crucial implications for the outcome of the analysis.

  14. Adapting environmental function analysis for management of protected areas in small islands--case of Pico Island (the Azores).

    Science.gov (United States)

    Calado, Helena; Bragagnolo, Chiara; Silva, Susana; Vergílio, Marta

    2016-04-15

    Protected areas (PAs) are considered key priorities for ensuring long-term sustainability of small islands. The traditional approach of conservation versus development is currently being replaced by an approach of "win-win" relationships. During the last decades PAs have been increasingly requested to simultaneously ensure biodiversity conservation, mainstream ecosystem services into main development policies, and accounting for leisure-related revenues to sustain local and regional economies. Following this new paradigm, the Smartparks project (Planning and Management System for Small Islands Protected Areas), encompassing this study, aimed at an innovative approach for supporting the management of PAs in small islands. In this study, we propose a methodology based on Environmental Functional Analyses (EFA) to compare the potential for conservation and the potential for use of PAs that can be used not only on small islands but also in other territories. For this purpose, a set of environmental and socio-economic components was defined and selected indicators describing each component to calculate conservation and use/development functions of PAs were established. Pico Island, in the Azores archipelago (Portugal), was selected as the case study for testing the methodology. The EFA for all PAs of Pico Island was performed identifying those with more potential for conservation or for development of human activities, and also those with high levels of conflict. A total of 34 indicators was applied (assigning a value from 1 to 3) to the 22 PAs composing the INP of Pico Island: 44% were scored with a value of 1, in both ecological and social components; 22% and 29% were scored 3 in ecological and social components respectively. Social indicators were generally considered less important than environmental ones. In general, PAs presented higher values for conservation. The results further show that the potential for conservation and/or development was consistent with the

  15. Adapting to climate change despite scientific uncertainty: A case study of coastal protection from sea-level rise in Kiribati

    Science.gov (United States)

    Donner, S. D.

    2013-12-01

    Climate change adaptation is an increasing focus of international aid. At recent meetings of the parties to the United Nations Framework Convention on Climate Change (UNFCCC), the developed world agreed to rapidly increase international assistance to help developing countries, like the low-lying island nation of Kiribati, respond to the impacts of climate change. These emerging adaptation efforts must proceed despite the large and partially irreducible scientific uncertainty about the magnitude of those future climate impacts. In this study, we use the example of efforts to adapt to sea-level rise in Kiribati to document the challenges facing such internationally-funded climate change adaptation projects given the scientific uncertainty about climate impacts. Drawing on field and document research, we describe the scientific uncertainty about projected sea-level rise in Tarawa, the capital of Kiribati, how that uncertainty can create trade-offs between adaptation measures, and the social, political and economic context in which adaptation decisions must be made. The analysis shows there is no 'silver bullet' adaptation strategy in countries like Kiribati, given the long-term scientific uncertainty about sea-level rise and the environment of climate change aid. The existence of irreducible scientific uncertainty does not preclude effective climate change adaptation, but instead requires adaptation programs that embrace multiple strategies and planning horizons, and continually build on and re-adjust previous investments. This work highlights the importance of sustained international climate change financing, as proposed in UNFCCC negotiations.

  16. Development and Standardization of the Diagnostic Adaptive Behavior Scale: Application of Item Response Theory to the Assessment of Adaptive Behavior

    Science.gov (United States)

    Tassé, Marc J.; Schalock, Robert L.; Thissen, David; Balboni, Giulia; Bersani, Henry, Jr.; Borthwick-Duffy, Sharon A.; Spreat, Scott; Widaman, Keith F.; Zhang, Dalun; Navas, Patricia

    2016-01-01

    The Diagnostic Adaptive Behavior Scale (DABS) was developed using item response theory (IRT) methods and was constructed to provide the most precise and valid adaptive behavior information at or near the cutoff point of making a decision regarding a diagnosis of intellectual disability. The DABS initial item pool consisted of 260 items. Using IRT…

  17. Development and Climate Change: A Mainstreaming Approach for Assessing Economic, Social, and Environmental Impacts of Adaptation Measures

    DEFF Research Database (Denmark)

    Halsnæs, Kirsten; Trærup, Sara Lærke Meltofte

    2009-01-01

    The paper introduces the so-called climate change mainstreaming approach, where vulnerability and adaptation measures are assessed in the context of general development policy objectives. The approach is based on the application of a limited set of indicators. These indicators are selected...... as representatives of focal development policy objectives, and a stepwise approach for addressing climate change impacts, development linkages, and the economic, social and environmental dimensions related to vulnerability and adaptation are introduced. Within this context it is illustrated using three case studies...... how development policy indicators in practice can be used to assess climate change impacts and adaptation measures based on three case studies, namely a road project in flood prone areas of Mozambique, rainwater harvesting in the agricultural sector in Tanzania and malaria protection in Tanzania...

  18. Progesterone-based contraceptives reduce adaptive immune responses and protection against sequential influenza A virus infections.

    Science.gov (United States)

    Hall, Olivia J; Nachbagauer, Raffael; Vermillion, Meghan S; Fink, Ashley L; Phuong, Vanessa; Krammer, Florian; Klein, Sabra L

    2017-02-08

    In addition to their intended use, progesterone (P4)-based contraceptives promote anti-inflammatory immune responses, yet their effects on the outcome of infectious diseases, including influenza A virus (IAV), are rarely evaluated. To evaluate their impact on immune responses to sequential IAV infections, adult female mice were treated with placebo or one of two progestins, P4 or levonorgestrel (LNG), and infected with mouse adapted (ma) H1N1 virus. Treatment with P4 or LNG reduced morbidity, but had no effect on pulmonary virus titers, during primary H1N1 infection as compared to placebo treatment. In serum and bronchoalveolar lavage fluid, total anti-IAV IgG and IgA titers and virus neutralizing antibody titers, but not hemagglutinin stalk antibody titers, were lower in progestin-treated mice as compared with placebo-treated mice. Females were challenged six weeks later with either a maH1N1 drift variant (maH1N1dv) or maH3N2 IAV. Protection following infection with the maH1N1dv was similar among all groups. In contrast, following challenge with maH3N2, progestin treatment reduced survival as well as numbers and activity of H1N1- and H3N2-specific memory CD8+ T cells, including tissue resident cells, compared with placebo treatment. In contrast to primary IAV infection, progestin treatment increased neutralizing and IgG antibody titers against both challenge viruses compared with placebo treatment. While the immunomodulatory properties of progestins protected naïve females against severe outcome from IAV infection, it made them more susceptible to secondary challenge with a heterologous IAV, despite improving their antibody responses against a secondary IAV infection. Taken together, the immunomodulatory effects of progestins differentially regulate the outcome of infection depending on exposure history.IMPORTANCE The impact of hormone-based contraceptives on the outcome of infectious diseases outside of the reproductive tract is rarely considered. Using a mouse

  19. ADAPTIVE SUBSYSTEM FOR DETECTING AND PREVENTING ANOMALIES AS A PROTECTION MEANS AGAINST NETWORK ATTACKS

    Directory of Open Access Journals (Sweden)

    Simankov V. S.

    2015-06-01

    Full Text Available This article describes the results of networks anomalies detection system based on modular adaptive approach practical implementation. The list of specific modules used in the practical implementation of IPS, their architecture, algorithms, software, organizational and technical support determined at technical working design based on the results of the audit, evaluation and risk analysis. In the general list of modules (subsystems we may include: intrusion detection and prevention (IPS / IDS subsystems; monitoring, data collection, and event correlation, administration and management subsystem and others. We have demonstrated the specificity of formation requirements for the basic mechanisms of the subsystems in terms of development and implementation of specific architecture with some examples, plus practically implemented structure of system modules, as well as organizational and technical support system functioning

  20. Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins.

    Science.gov (United States)

    Kaya, Alaattin; Gerashchenko, Maxim V; Seim, Inge; Labarre, Jean; Toledano, Michel B; Gladyshev, Vadim N

    2015-08-25

    Aerobic respiration is a fundamental energy-generating process; however, there is cost associated with living in an oxygen-rich environment, because partially reduced oxygen species can damage cellular components. Organisms evolved enzymes that alleviate this damage and protect the intracellular milieu, most notably thiol peroxidases, which are abundant and conserved enzymes that mediate hydrogen peroxide signaling and act as the first line of defense against oxidants in nearly all living organisms. Deletion of all eight thiol peroxidase genes in yeast (∆8 strain) is not lethal, but results in slow growth and a high mutation rate. Here we characterized mechanisms that allow yeast cells to survive under conditions of thiol peroxidase deficiency. Two independent ∆8 strains increased mitochondrial content, altered mitochondrial distribution, and became dependent on respiration for growth but they were not hypersensitive to H2O2. In addition, both strains independently acquired a second copy of chromosome XI and increased expression of genes encoded by it. Survival of ∆8 cells was dependent on mitochondrial cytochrome-c peroxidase (CCP1) and UTH1, present on chromosome XI. Coexpression of these genes in ∆8 cells led to the elimination of the extra copy of chromosome XI and improved cell growth, whereas deletion of either gene was lethal. Thus, thiol peroxidase deficiency requires dosage compensation of CCP1 and UTH1 via chromosome XI aneuploidy, wherein these proteins support hydroperoxide removal with the reducing equivalents generated by the electron transport chain. To our knowledge, this is the first evidence of adaptive aneuploidy counteracting oxidative stress.

  1. THE EXTENSION OF GEOGRAPHICAL INDICATION PROTECTION: NECESSARY FOR DEVELOPING COUNTRY

    Directory of Open Access Journals (Sweden)

    Mas Rahmah

    2015-02-01

    Full Text Available This paper analyses the need of extension of Geographical Indication (GI protection since the current protection under Trade Related Aspect of Intellectual Property Rights (TRIPS is insufficient to cover all products as a result of discriminatory provisions in TRIPS regulating a greater protection to wines and spirits only and different level of GI protection under Article 22 and Article 23 TRIPS. This paper then assumes that the extensive GI protection for all products should be supported because it would give greater benefits particularly to developing countries such as prevent the free riding, attract regional investment and obtain market power.   Perlindungan Indikasi Geografis (IG perlu diperluas tidak hanya pada produk tertentu seperti wines danspiritskarena perlindungan IG diatur di dalam TRIPS tidak cukup memberikan perlindungan kepada semua produk sebagai akibat perbedaan pengaturan di TRIPS yang memberikan perlindungan lebih kepada wines danspirits saja dan adanya perbedaan tingkat perlindungan pada Pasal 22 dan 23 TRIPS. Perluasan perlindungan IG harus didukung karena akan memberikan manfaat khususnya kepada negara berkembang. Perluasan perlindungan IG dapat melarang pemboncengan reputasi, menarik investasi dan meningkatkan kekuatan produk negara berkembang di pasaran.

  2. Adaptive coordination of protective relaying in Ehv transmission using artificial intelligence and parallel processing; Esquema adaptativo para la coordinacion de reles de proteccion en redes de transmission de alta tension incorporando tecnicas de inteligencia artificial y procesamiento en paralelo

    Energy Technology Data Exchange (ETDEWEB)

    Orduna, E.; Garces, F; Rivera, J.F. [Univ. Nacional de San Juan, San Juan (Argentina). Instituto de Energia Eletrica; Handschin, E. [Dortmund Univ. (Germany). Lehrstuhl fuer Elektrische Energieversorgung

    1994-12-31

    The protection systems of electric power systems have as function to detect failures as soon possible and isolate the failed component. Considering that the main protection system may fail, protection in the elements adjacent to the failed one must act as a spare, observing an actuation time delay to accomplish selectivity criteria. This work presents the system named CORPRO developed in order to enable the fast determination of adjustments of relays coordination in electric power transmission lines for real time adaptive protection system 9 refs., 8 figs., 4 tabs.

  3. Development of a computerized adaptive test for Schizotypy assessment.

    Directory of Open Access Journals (Sweden)

    Eduardo Fonseca-Pedrero

    Full Text Available BACKGROUND: Schizotypal traits in adolescents from the general population represent the behavioral expression of liability for psychotic disorders. Schizotypy assessment in this sector of population has advanced considerably in the last few years; however, it is necessary to incorporate recent advances in psychological and educational measurement. OBJECTIVE: The main goal of this study was to develop a Computerized Adaptive Test (CAT to evaluate schizotypy through "The Oviedo Questionnaire for Schizotypy Assessment" (ESQUIZO-Q, in non-clinical adolescents. METHODS: The final sample consisted of 3,056 participants, 1,469 males, with a mean age of 15.9 years (SD=1.2. RESULTS: The results indicated that the ESQUIZO-Q scores presented adequate psychometric properties under both Classical Test Theory and Item Response Theory. The Information Function estimated using the Gradual Response Model indicated that the item pool effectively assesses schizotypy at the high end of the latent trait. The correlation between the CAT total scores and the paper-and-pencil test was 0.92. The mean number of presented items in the CAT with the standard error fixed at ≤ 0.30 was of 34 items. CONCLUSION: The CAT showed adequate psychometric properties for schizotypy assessment in the general adolescent population. The ESQUIZO-Q adaptive version could be used as a screening method for the detection of adolescents at risk for psychosis in both educational and mental health settings.

  4. Development of adaptive sensorimotor control in infant sitting posture.

    Science.gov (United States)

    Chen, Li-Chiou; Jeka, John; Clark, Jane E

    2016-03-01

    A reliable and adaptive relationship between action and perception is necessary for postural control. Our understanding of how this adaptive sensorimotor control develops during infancy is very limited. This study examines the dynamic visual-postural relationship during early development. Twenty healthy infants were divided into 4 developmental groups (each n=5): sitting onset, standing alone, walking onset, and 1-year post-walking. During the experiment, the infant sat independently in a virtual moving-room in which anterior-posterior oscillations of visual motion were presented using a sum-of-sines technique with five input frequencies (from 0.12 to 1.24 Hz). Infants were tested in five conditions that varied in the amplitude of visual motion (from 0 to 8.64 cm). Gain and phase responses of infants' postural sway were analyzed. Our results showed that infants, from a few months post-sitting to 1 year post-walking, were able to control their sitting posture in response to various frequency and amplitude properties of the visual motion. Infants showed an adult-like inverted-U pattern for the frequency response to visual inputs with the highest gain at 0.52 and 0.76 Hz. As the visual motion amplitude increased, the gain response decreased. For the phase response, an adult-like frequency-dependent pattern was observed in all amplitude conditions for the experienced walkers. Newly sitting infants, however, showed variable postural behavior and did not systemically respond to the visual stimulus. Our results suggest that visual-postural entrainment and sensory re-weighting are fundamental processes that are present after a few months post sitting. Sensorimotor refinement during early postural development may result from the interactions of improved self-motion control and enhanced perceptual abilities.

  5. A practical application and implementation of adaptive techniques using neural networks in autoreclose protection and system control

    Energy Technology Data Exchange (ETDEWEB)

    Gardiner, I.P.

    1997-12-31

    Reyrolle Protection have carried out research in conjunction with Bath University into applying adaptive techniques to autoreclose schemes and have produced an algorithm based on an artificial neural network which can recognise when it is ``safe to reclose`` and when it is ``unsafe to reclose``. This algorithm is based on examination of the induced voltage on the faulted phase and by applying pattern recognition techniques determines when the secondary arc extinguishes. Significant operational advantages can now be realised using this technology resulting in changes to existing operational philosophy. Conventional autoreclose relays applied to the system have followed the philosophy of ``reclose to restore the system``, but a progression from this philosophy to ``reclose only if safe to do so`` can now be made using this adaptive approach. With this adaptive technique the main requirement remains to protect the investment i.e. the system, by reducing damaging shocks and voltage dips and maintaining continuity of supply. The adaptive technique can be incorporated into a variety of schemes which will act to further this goal in comparison with conventional autoreclose. (Author)

  6. Innovative Development of Fishery and Ecological Protection of Poyang Lake

    Institute of Scientific and Technical Information of China (English)

    Xiaofeng FU; Minghe XIAO; Guozhen FU

    2016-01-01

    Fishery is an essential part of economic and ecological civilization construction of Poyang Lake Ecological Economic Zone. Taking fishery development and ecological protection of Poyang Lake as research object,this paper elaborated the relation between fishery development and ecological protection from physiological characteristics and functions of fish species by the method of field survey and consulting related data. Finally,it came up with recommendations of increasing plagiognathops microlepis and Xenocypris davidi Bleeker and adopting and deepening healthy ecological and water body stratification. Besides,government organizations,local supervision authorities,scientific research institutions,and enterprise operating entities should jointly maintain and promote breakthrough mechanism for ecological balance of Poyang Lake water system.

  7. Danish Mortgage Finance, Property Rights Protection and Economic Development

    DEFF Research Database (Denmark)

    Haldrup, Karin

    of screening methods for assessing the readiness for such transplantation depends on a deeper understanding of three large domains: A) Mortgage Finance, B) Cadastre and Land Registration; and C) Economic Development; and the interrelations between these three areas. In particular the thesis has focused...... on the requirements of infrastructure in respect to protecting ‘security of collateral’, and on international monitoring systems providing information on the status of what cadaster, real property registration and other functions of importance for securing collateral and for valuation of properties. In the absence...... of data on the status of land registration (and of reliable ratings of protection of property rights), it was found that macro-economic indicators could serve as indicators of readiness. Findings included propositions on prerequisites for readiness of mortgage finance development and proposals concerning...

  8. Private power development and environmental protection in India

    Energy Technology Data Exchange (ETDEWEB)

    Das, S.; Wilbanks, T.J.

    1997-12-01

    This report assesses relationships between private power development in India and environmental protection in that country. The central question is whether private firms generating and distributing electricity in developing countries will do a better or a worse job in environmental protection, as a part of their overall corporate responsibility, than public-sector institutions. After reviewing the fundamental question, why it is asked, and the context in which it operates in the nation of India, this report continues with an analysis of available information, quantitative and qualitative, that can help to resolve the issues in the particular case of India. Finally, it ends with conclusions from the analysis and recommendations for reducing remaining uncertainties in the future.

  9. Adaptive Management Methods to Protect the California Sacramento-San Joaquin Delta Water Resource

    Science.gov (United States)

    Bubenheim, David

    2016-01-01

    The California Sacramento-San Joaquin River Delta is the hub for California's water supply, conveying water from Northern to Southern California agriculture and communities while supporting important ecosystem services, agriculture, and communities in the Delta. Changes in climate, long-term drought, water quality changes, and expansion of invasive aquatic plants threatens ecosystems, impedes ecosystem restoration, and is economically, environmentally, and sociologically detrimental to the San Francisco Bay/California Delta complex. NASA Ames Research Center and the USDA-ARS partnered with the State of California and local governments to develop science-based, adaptive-management strategies for the Sacramento-San Joaquin Delta. The project combines science, operations, and economics related to integrated management scenarios for aquatic weeds to help land and waterway managers make science-informed decisions regarding management and outcomes. The team provides a comprehensive understanding of agricultural and urban land use in the Delta and the major water sheds (San Joaquin/Sacramento) supplying the Delta and interaction with drought and climate impacts on the environment, water quality, and weed growth. The team recommends conservation and modified land-use practices and aids local Delta stakeholders in developing management strategies. New remote sensing tools have been developed to enhance ability to assess conditions, inform decision support tools, and monitor management practices. Science gaps in understanding how native and invasive plants respond to altered environmental conditions are being filled and provide critical biological response parameters for Delta-SWAT simulation modeling. Operational agencies such as the California Department of Boating and Waterways provide testing and act as initial adopter of decision support tools. Methods developed by the project can become routine land and water management tools in complex river delta systems.

  10. Collateral Damage: Detrimental Effect of Antibiotics on the Development of Protective Immune Memory.

    Science.gov (United States)

    Benoun, Joseph M; Labuda, Jasmine C; McSorley, Stephen J

    2016-12-20

    Antibiotic intervention is an effective treatment strategy for many bacterial infections and liberates bacterial antigens and stimulatory products that can induce an inflammatory response. Despite the opportunity for bacterial killing to enhance the development of adaptive immunity, patients treated successfully with antibiotics can suffer from reinfection. Studies in mouse models of Salmonella and Chlamydia infection also demonstrate that early antibiotic intervention reduces host protective immunity to subsequent infection. This heightened susceptibility to reinfection correlates with poor development of Th1 and antibody responses in antibiotic-treated mice but can be overcome by delayed antibiotic intervention, thus suggesting a requirement for sustained T cell stimulation for protection. Although the contribution of memory T cell subsets is imperfectly understood in both of these infection models, a protective role for noncirculating memory cells is suggested by recent studies. Together, these data propose a model where antibiotic treatment specifically interrupts tissue-resident memory T cell formation. Greater understanding of the mechanistic basis of this phenomenon might suggest therapeutic interventions to restore a protective memory response in antibiotic-treated patients, thus reducing the incidence of reinfection. Copyright © 2016 Benoun et al.

  11. Development of Functional Foods for Body Protection Using Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Jo, S. K.; Jung, U. H.; Park, H. R.

    2007-07-15

    We have previously developed two herbal compositions(HemoHIM, HemoTonic) that protects immune/hematopoietic system and self-renewal tissues against radiation and enhances immune/hematopoietic functions. In this study, we tried to expand its usability by verifying its protective activity against various harmful stimuli as well as radiation. HemoHIM was shown to be highly effective in reducing immune/hematopoietic damage, particularly, normalizing the Th1/Th2 imbalance, which seemed to be a result of increased production of IL-12p70 by APC and enhanced NK cell activity. Also HemoHIM was shown to have protective activities against UV-induced skin damage, immune system damage by an anticancer drug (CP), immune depression by old age and stress, and inflammation. Finally it was confirmed in a human study that HemoHIM improves the immune cell functions and cytokine production. Based on these results, HemoHIM has been approved as a health functional food for immunomodulation by Korea FDA and succeeded in its industrialization. Meanwhile, to develop functional foods for the reduction of chronic radiation damage (carcinogenesis), we have screened natural products for inhibitory activities against carcinogenesis-related factors, and developed two anti-carcinogenic compositions. Also 6 single compounds were isolated and identified from radioprotective natural products and elucidated some synergistic protection by several single compounds and established a basis for the development of advanced technology for radioprotection. Also, to obtain the applicability of radiation technology for the safe sanitatation and distribution of functional food materials, we verified the toxicological safety, stability of activity and active components of irradiated medicinal herbs

  12. Contribution to developing the environment radiation protection methodology

    Energy Technology Data Exchange (ETDEWEB)

    Oudalova, A. [Institute of Atomic Power Engineering NRNU MEPhI (Russian Federation); Alexakhin, R.; Dubynina, M. [Russian Institute of Agricultural Radiology and Agroecology (Russian Federation)

    2014-07-01

    The environment sustainable development and biota protection, including the environment radiation protection are issues of nowadays interest in the society. An activity is ongoing on the development of a system of radiation protection for non-human biota. Anthropocentric and eco-centric principles are widely discussed. ICRP Publications 103, 108, 114 and many other reports and articles refer to the topic of environmental protection, reference animals and plants set, corresponding transfer parameters, dose models and derived consideration reference levels. There is still an open field for discussion of methods and approaches to get well-established procedure to assess environmental risks of radiation impacts to different organisms, populations and ecosystems. A huge work has been done by the ICRP and other organizations and research groups to develop and systematize approaches for this difficult subject. This activity, however, is not everywhere well-known and perceived, and more efforts are needed to bring ideas of eco-centric strategy in the environment radiation protection not only to public but to specialists in many countries as well. One of the main points of interest is an assessment of critical doses and doses rates for flora and fauna species. Some aspects of a possible procedure to find their estimates are studied in this work, including criteria for datasets of good quality, models of dose dependence, sensitivity of different umbrella endpoints and methods of original massive datasets treatment. Estimates are done based on information gathered in a database on radiation-induced effects in plants. Data on biological effects in plants (umbrella endpoints of reproductive potential, survival, morbidity, morphological, biochemical, and genetic effects) in dependence on dose and dose rates of ionizing radiation have been collected from reviewed publications and maintained in MS Access format. The database now contains about 7000 datasets and 25000 records

  13. People-oriented Development and Human Rights Protection for Criminals

    Institute of Scientific and Technical Information of China (English)

    LI YUQIAN

    2011-01-01

    @@ People-oriented development refers to the economic and social integrative development that regards human beings as the orientation and subject of economic and social development and considers the development of human beings the essence, objective, momentum and symbol of development.One of its important connotations is to protect human beings' rights and interests in all links and works of economic and social development.On December 10,2008, Hu Jintao, secretary general of the CPC Central Committee, clarified that "We will, as always, adhere to people-oriented principles in building a well-off society in an all-round way and accelerating the process of socialist modernization" in his letter to the China Society for Human Rights Studies.

  14. SUBSTANTIATING THE DEVELOPMENT STRATEGIES FOR TOURISM IN PROTECTED AREAS

    Directory of Open Access Journals (Sweden)

    Mirela Costencu

    2014-01-01

    Full Text Available The protected natural areas, irrespective of their classification modality or the motivations they propose, have become more and more attractive for tourists. However, in time, the increasing touristic flows they attract, often developed in an uncontrolled manner, lead to the erosion of the space and the degradation of ecosystems. Developing tourism on sustainable principles, with the appropriate balance of the two functions of a protected area – the scientific and the touristic function – should start from the analysis of this form of tourism and of the development opportunities and limits regarded from the perspective of the external environment, and from the particularisation of the concept “site’s tourist reception capacity”. Destination areas should meet the economic, social and ecological requirements in competition, so that they observe the integrity of natural resources and of local communities. The upper limit of the number of visits allowed in a protected area is purposefully set at a level below the identified level of accepted use, so that, in the long run, the environment could be able to cover the possible increases occurred in the number of tourists, without subjecting the environment to further harm.

  15. Development of large aperture elements for active and adaptive optics

    Directory of Open Access Journals (Sweden)

    Stranakova E.

    2013-05-01

    Full Text Available Large-aperture elements for laser active and adaptive optics are investigated in collaboration within IOP AcSci CR, FEng CTU and 5M. A bimorph deformable mirror for high-power lasers based on a lightweight structure with a composite core is currently in development. In order to realize a sufficiently large working aperture we are using new technologies for production of core, bimorph actuator and DM reflector. Detailed simulation of components and structure is validated by measurement and testing. A research of DM actuation and response of a complicated mirror structure needed for an accurate control of a deformation is performed. Testing of samples and subscale measurements are currently performed, measurement of a complete structure is in preparation.

  16. Adaptation to acrolein through upregulating the protection by glutathione in human bronchial epithelial cells: the materialization of the hormesis concept.

    Science.gov (United States)

    Sthijns, Mireille M J P E; Randall, Matthew J; Bast, Aalt; Haenen, Guido R M M

    2014-04-18

    Acrolein is a thiol reactive compound present in cigarette smoke and plays a pivotal role in the deleterious effects of smoking. Acrolein causes toxicity in human bronchial epithelial cells in a dose dependent manner. GSH forms the first line of defense against acrolein-induced toxicity. At high doses of acrolein (⩾10 μM) the capacity of the cellular protection by GSH is overwhelmed and GSH is not able to quench all the acrolein, resulting in cytotoxicity. At a relatively low dose of acrolein (3 μM), no cytotoxicity is observed due to protection by GSH. Moreover we found that exposure to a low dose of acrolein protects cells against the toxic effect of a second higher dose of acrolein. The adaptation to acrolein is induced via Nrf2 mediated gene expression of γ-glutamylcysteine synthetase leading to elevated GSH levels. This upregulation of the protection by GSH demonstrates a hormetic response to acrolein. Hormesis is an adaptive or compensatory response induced by a relatively subtle challenge of homeostasis by a toxic compound. Insight into the mechanism of hormesis is mandatory for a more accurate societal regulation of toxic compounds.

  17. Adaptive settings of distance relay for MOV-protected series compensated line with distributed capacitance considering wind power

    Science.gov (United States)

    Sivov, Oleg Viktorovich

    Series compensated lines are protected from overvoltage by metal-oxide-varistors (MOVs) connected in parallel with the capacitor bank. The nonlinear characteristics of MOV devices add complexity to fault analysis and distance protection operation. During faults, the impedance of the line is modified by an equivalent impedance of the parallel MOV/capacitor circuit, which affects the distance protection. The intermittent wind generation introduces additional complexity to the system performance and distance protection. Wind variation affects the fault current level and equivalent MOV/capacitor impedance during a fault, and hence the distance relay operation. This thesis studies the impact of the intermittent wind power generation on the operation of MOV during faults. For the purpose of simulation, an equivalent wind farm model is proposed to generate a wind generation profile using wind farm generation from California independent system operator (ISO) as a guide for wind power variation to perform the study. The IEEE 12-bus test system is modified to include MOV-protected series capacitor and the equivalent wind farm model. The modified test system is simulated in the MATLAB/Simulink environment. The study has been achieved considering three phase and single line to ground (SLG) faults on the series compensated line to show the effect of wind variation on the MOV operation. This thesis proposes an adaptive setting method for the mho relay distance protection of series compensated line considering effects of wind power variation and MOV operation. The distributed parameters of a transmission line are taken into account to avoid overreaching and underreaching of distance relays. The study shows that variable wind power affects system power flow and fault current in the compensated line during a fault which affects the operation of MOVs for different fault conditions. The equivalent per-phase impedance of the MOV/capacitor circuit has an effect on the system operation

  18. Assessment of the effectiveness of participatory developed adaptation strategies for HCMC

    Directory of Open Access Journals (Sweden)

    R. Lasage

    2014-01-01

    Full Text Available Coastal cities are vulnerable to flooding, and flood risk to coastal cities will increase due to sea-level rise. Moreover, especially Asian cities are subject to considerable population growth and associated urban developments, increasing this risk even more. Empirical data on vulnerability and the cost and benefits of flood risk reducing measures are therefore paramount for sustainable development of these cities. This paper presents an approach to explore the impacts of sea level rise and socio-economic developments on flood risk for the flood prone District 4 in Ho Chi Minh City, Vietnam, and to develop and evaluate the effects of different adaptation strategies (new levees, dry- and wet flood proofing of buildings. A flood damage model was developed to simulate current and future flood risk using the results from a household survey to establish stage-damage curves for residential buildings. the model has been used to assess the effects of several participatory developed adaptation strategies to reduce flood risk, expressed in Expected Annual Damage (EAD. Adaptation strategies were evaluated assuming combinations of both sea level scenarios and land use scenarios. Together with information on costs of these strategies, we calculated the benefit-cost ratio and net present value for the adaptation strategies until 2100, taking into account depreciation rates of 2.5% and 5%. The results of this modeling study indicate that the current flood risk in District 4 is 0.31 million USD yr–1, increasing up to 0.78 million USD yr–1 in 2100. The net present value and benefit-cost ratios using a discount rate of 5% range from USD −107 to −1.5 million, and from 0.086 to 0.796 for the different strategies. Using a discount rate of 2.5% leads to an increase in both net present value and benefit cost ratio. The adaptation strategies wet proofing and dry proofing generate the best results using these economic indicators. The information on different

  19. Assessment of the effectiveness of participatory developed adaptation strategies for HCMC

    Science.gov (United States)

    Lasage, R.; Veldkamp, T. I. E.; de Moel, H.; Van, T. C.; Phi, H. L.; Vellinga, P.; Aerts, J. C. J. H.

    2014-01-01

    Coastal cities are vulnerable to flooding, and flood risk to coastal cities will increase due to sea-level rise. Moreover, especially Asian cities are subject to considerable population growth and associated urban developments, increasing this risk even more. Empirical data on vulnerability and the cost and benefits of flood risk reducing measures are therefore paramount for sustainable development of these cities. This paper presents an approach to explore the impacts of sea level rise and socio-economic developments on flood risk for the flood prone District 4 in Ho Chi Minh City, Vietnam, and to develop and evaluate the effects of different adaptation strategies (new levees, dry- and wet flood proofing of buildings). A flood damage model was developed to simulate current and future flood risk using the results from a household survey to establish stage-damage curves for residential buildings. the model has been used to assess the effects of several participatory developed adaptation strategies to reduce flood risk, expressed in Expected Annual Damage (EAD). Adaptation strategies were evaluated assuming combinations of both sea level scenarios and land use scenarios. Together with information on costs of these strategies, we calculated the benefit-cost ratio and net present value for the adaptation strategies until 2100, taking into account depreciation rates of 2.5% and 5%. The results of this modeling study indicate that the current flood risk in District 4 is 0.31 million USD yr-1, increasing up to 0.78 million USD yr-1 in 2100. The net present value and benefit-cost ratios using a discount rate of 5% range from USD -107 to -1.5 million, and from 0.086 to 0.796 for the different strategies. Using a discount rate of 2.5% leads to an increase in both net present value and benefit cost ratio. The adaptation strategies wet proofing and dry proofing generate the best results using these economic indicators. The information on different strategies will be used by

  20. Career Adaptability as a Strategic Competence for Career Development: An Exploratory Study of Its Key Predictors

    Science.gov (United States)

    Bocciardi, Federica; Caputo, Andrea; Fregonese, Chiara; Langher, Viviana; Sartori, Riccardo

    2017-01-01

    Purpose: In the current labour market, the competence to adapt is becoming significantly relevant for career development and career success. The construct of career adaptability, i.e. the capability to adapt to changing career-related circumstances and predict advancement in career development, seems to provide a fruitful scientific base for…

  1. Environment Protection as a Presumption of Sustainable Development

    Directory of Open Access Journals (Sweden)

    Jelena Premović

    2013-06-01

    Full Text Available Rapid economic growth and irrational use of natural resources in the last decades of the XX century have influenced the changes in the environmental sphere and to specific environmental problems. These processes in the global economy and society, caused a disturbance of the environment by increasing pollution of the environment. Emerging problems of the entire human society can be solved by applying the concept of sustainable growth and development and raising awareness about the necessity of implementation of basic environmental standards in business. In order to reduce the harmful effects of production processes on the environment and to help meet the objective of sustainable development outlined at the UN Conference on Environment and Development in Rio De Janeiro in 1992 the ISO 14000 Standards were created. The essence of sustainable development is responsible development that meets the current needs a way to rationally use natural resources to ensure meeting the needs of future generations and environment protection.

  2. The evolution of cultural adaptations: Fijian food taboos protect against dangerous marine toxins.

    Science.gov (United States)

    Henrich, Joseph; Henrich, Natalie

    2010-12-22

    The application of evolutionary theory to understanding the origins of our species' capacities for social learning has generated key insights into cultural evolution. By focusing on how our psychology has evolved to adaptively extract beliefs and practices by observing others, theorists have hypothesized how social learning can, over generations, give rise to culturally evolved adaptations. While much field research documents the subtle ways in which culturally transmitted beliefs and practices adapt people to their local environments, and much experimental work reveals the predicted patterns of social learning, little research connects real-world adaptive cultural traits to the patterns of transmission predicted by these theories. Addressing this gap, we show how food taboos for pregnant and lactating women in Fiji selectively target the most toxic marine species, effectively reducing a woman's chances of fish poisoning by 30 per cent during pregnancy and 60 per cent during breastfeeding. We further analyse how these taboos are transmitted, showing support for cultural evolutionary models that combine familial transmission with selective learning from locally prestigious individuals. In addition, we explore how particular aspects of human cognitive processes increase the frequency of some non-adaptive taboos. This case demonstrates how evolutionary theory can be deployed to explain both adaptive and non-adaptive behavioural patterns.

  3. Issues in Developing Adaptive Learning Management Systems for Higher Education Institutions

    NARCIS (Netherlands)

    Boticario, Jesús; Santos, Olga

    2006-01-01

    Please, cite this publication as: Boticario, J. & Santos, O. (2006). Issues in Developing Adaptive Learning Management Systems for Higher Education Institutions. Proceedings of Adaptive Hypermedia. June, Dublin, Ireland. Retrieved June 30th, 2006, from http://dspace.learningnetworks.org

  4. Adaptive control for solar energy based DC microgrid system development

    Science.gov (United States)

    Zhang, Qinhao

    During the upgrading of current electric power grid, it is expected to develop smarter, more robust and more reliable power systems integrated with distributed generations. To realize these objectives, traditional control techniques are no longer effective in either stabilizing systems or delivering optimal and robust performances. Therefore, development of advanced control methods has received increasing attention in power engineering. This work addresses two specific problems in the control of solar panel based microgrid systems. First, a new control scheme is proposed for the microgrid systems to achieve optimal energy conversion ratio in the solar panels. The control system can optimize the efficiency of the maximum power point tracking (MPPT) algorithm by implementing two layers of adaptive control. Such a hierarchical control architecture has greatly improved the system performance, which is validated through both mathematical analysis and computer simulation. Second, in the development of the microgrid transmission system, the issues related to the tele-communication delay and constant power load (CPL)'s negative incremental impedance are investigated. A reference model based method is proposed for pole and zero placements that address the challenges of the time delay and CPL in closed-loop control. The effectiveness of the proposed modeling and control design methods are demonstrated in a simulation testbed. Practical aspects of the proposed methods for general microgrid systems are also discussed.

  5. Development of adaptive resonator techniques for high-power lasers

    Energy Technology Data Exchange (ETDEWEB)

    An, J; Brase, J; Carrano, C; Dane, C B; Flath, L; Fochs, S; Hurd, R; Kartz, M; Sawvel, R

    1999-07-12

    The design of an adaptive wavefront control system for a high-power Nd:Glass laser will be presented. Features of this system include: an unstable resonator in confocal configuration, a multi-module slab amplifier, and real-time intracavity adaptive phase control using deformable mirrors and high-speed wavefront sensors. Experimental results demonstrate the adaptive correction of an aberrated passive resonator (no gain).

  6. Development of quantum-based adaptive neuro-fuzzy networks.

    Science.gov (United States)

    Kim, Sung-Suk; Kwak, Keun-Chang

    2010-02-01

    In this study, we are concerned with a method for constructing quantum-based adaptive neuro-fuzzy networks (QANFNs) with a Takagi-Sugeno-Kang (TSK) fuzzy type based on the fuzzy granulation from a given input-output data set. For this purpose, we developed a systematic approach in producing automatic fuzzy rules based on fuzzy subtractive quantum clustering. This clustering technique is not only an extension of ideas inherent to scale-space and support-vector clustering but also represents an effective prototype that exhibits certain characteristics of the target system to be modeled from the fuzzy subtractive method. Furthermore, we developed linear-regression QANFN (LR-QANFN) as an incremental model to deal with localized nonlinearities of the system, so that all modeling discrepancies can be compensated. After adopting the construction of the linear regression as the first global model, we refined it through a series of local fuzzy if-then rules in order to capture the remaining localized characteristics. The experimental results revealed that the proposed QANFN and LR-QANFN yielded a better performance in comparison with radial basis function networks and the linguistic model obtained in previous literature for an automobile mile-per-gallon prediction, Boston Housing data, and a coagulant dosing process in a water purification plant.

  7. Unequal Protection of Video Streaming through Adaptive Modulation with a Trizone Buffer over Bluetooth Enhanced Data Rate

    Directory of Open Access Journals (Sweden)

    Rouzbeh Razavi

    2007-12-01

    Full Text Available Bluetooth enhanced data rate wireless channel can support higher-quality video streams compared to previous versions of Bluetooth. Packet loss when transmitting compressed data has an effect on the delivered video quality that endures over multiple frames. To reduce the impact of radio frequency noise and interference, this paper proposes adaptive modulation based on content type at the video frame level and content importance at the macroblock level. Because the bit rate of protected data is reduced, the paper proposes buffer management to reduce the risk of buffer overflow. A trizone buffer is introduced, with a varying unequal protection policy in each zone. Application of this policy together with adaptive modulation results in up to 4 dB improvement in objective video quality compared to fixed rate scheme for an additive white Gaussian noise channel and around 10 dB for a Gilbert-Elliott channel. The paper also reports a consistent improvement in video quality over a scheme that adapts to channel conditions by varying the data rate without accounting for the video frame packet type or buffer congestion.

  8. Development of Protection and Control Unit for Distribution Substation

    Science.gov (United States)

    Iguchi, Fumiaki; Hayashi, Hideyuki; Takeuchi, Motohiro; Kido, Mitsuyasu; Kobayashi, Takashi; Yanaoka, Atsushi

    The Recently, electronics and IT technologies have been rapidly innovated and have been introduced to power system protection & control system to achieve high reliability, maintainability and more functionality. Concerning the distribution substation application, digital relays have been applied for more than 10 years. Because of a number of electronic devices used for it, product cost becomes higher. Also, products installed during the past high-growth period will be at the end of lifetime and will be replaced. Therefore, replacing market is expected to grow and the reduction of cost is demanded. Considering above mentioned background, second generation digital protection and control unit as a successor is designed to have following concepts. Functional integration based on advanced digital technologies, Ethernet LAN based indoor communication network, cost reduction and downsizing. Pondering above concepts, integration of protection and control function is adopted in contrary to the functional segregation applied to the previous system in order to achieve one-unit concept. Also the adoption of Ethernet LAN for inter-unit communication is objective. This report shows the development of second-generation digital relay for distribution substation, which is equipped with control function and Ethernet LAN by reducing the size of auxiliary transformer unit and the same size as previous product is realized.

  9. Development and Assessment of Advanced Reactor Core Protection System

    Science.gov (United States)

    in, Wang-Kee; Park, Young-Ho; Baeg, Seung-Yeob

    An advanced core protection system for a pressurized water reactor, Reactor Core Protection System(RCOPS), was developed by adopting a high performance hardware platform and optimal system configuration. The functional algorithms of the core protection system were also improved to enhance the plant availability by reducing unnecessary reactor trips and increasing operational margin. The RCOPS consists of four independent safety channels providing a two-out-of-four trip logic. The reliability analysis using the reliability block diagram method showed the unavailability of the RCOPS to be lower than the conventional system. The failure mode and effects analysis demonstrated that the RCOPS does not lose its intended safety functions for most failures. New algorithms for the RCOPS functional design were implemented in order to avoid unnecessary reactor trips by providing auxiliary pre-trip alarms and signal validation logic for the control rod position. The new algorithms in the RCOPS were verified by comparing the RCOPS calculations with reference results. The new thermal margin algorithm for the RCOPS was expected to increase the operational margin to the limit for Departure from Nucleate Boiling Ratio (DNBR) by approximately 1%.

  10. Development of Adaptive Kanji Learning System for Mobile Phone

    Science.gov (United States)

    Li, Mengmeng; Ogata, Hiroaki; Hou, Bin; Hashimoto, Satoshi; Liu, Yuqin; Uosaki, Noriko; Yano, Yoneo

    2010-01-01

    This paper describes an adaptive learning system based on mobile phone email to support the study of Japanese Kanji. In this study, the main emphasis is on using the adaptive learning to resolve one common problem of the mobile-based email or SMS language learning systems. To achieve this goal, the authors main efforts focus on three aspects:…

  11. Science-management collaborations: Developing adaptation options for National Forests

    Science.gov (United States)

    Forest Service U.S. Department of Agriculture

    2010-01-01

    Climate is constantly changing, prompting natural and managed ecosystems to adjust. As a natural process, adaptation refers to the reactive changes that species and ecosystems make in response to environmental changes. With human intervention, adaptation refers to management actions and decisions that help ecological, social, and economic systems accommodate challenges...

  12. Development of Oxidation Protection Coatings for Gamma Titanium Aluminide Alloys

    Science.gov (United States)

    Wallace, T. A.; Bird, R. K.; Sankaran, S. N.

    2003-01-01

    Metallic material systems play a key role in meeting the stringent weight and durability requirements for reusable launch vehicle (RLV) airframe hot structures. Gamma titanium aluminides (gamma-TiAl) have been identified as high-payoff materials for high-temperature applications. The low density and good elevated temperature mechanical properties of gamma-TiAl alloys make them attractive candidates for durable lightweight hot structure and thermal protection systems at temperatures as high as 871 C. However, oxidation significantly degrades gamma-TiAl alloys under the high-temperature service conditions associated with the RLV operating environment. This paper discusses ongoing efforts at NASA Langley Research Center to develop durable ultrathin coatings for protecting gamma-TiAl alloys from high-temperature oxidation environments. In addition to offering oxidation protection, these multifunctional coatings are being engineered to provide thermal control features to help minimize heat input into the hot structures. This paper describes the coating development effort and discusses the effects of long-term high-temperature exposures on the microstructure of coated and uncoated gamma-TiAl alloys. The alloy of primary consideration was the Plansee alloy gamma-Met, but limited studies of the newer alloy gamma-Met-PX were also included. The oxidation behavior of the uncoated materials was evaluated over the temperature range of 704 C to 871 C. Sol-gel-based coatings were applied to the gamma-TiAl samples by dipping and spraying, and the performance evaluated at 871 C. Results showed that the coatings improve the oxidation resistance, but that further development is necessary.

  13. Emotional Development and Adaptive Abilities in Adults with Intellectual Disability. A Correlation Study between the Scheme of Appraisal of Emotional Development (SAED) and Vineland Adaptive Behavior Scale (VABS)

    Science.gov (United States)

    La Malfa, Giampaolo; Lassi, Stefano; Bertelli, Marco; Albertini, Giorgio; Dosen, Anton

    2009-01-01

    The importance of emotional aspects in developing cognitive and social abilities has already been underlined by many authors even if there is no unanimous agreement on the factors constituting adaptive abilities, nor is there any on the way to measure them or on the relation between adaptive ability and cognitive level. The purposes of this study…

  14. Emotional Development and Adaptive Abilities in Adults with Intellectual Disability. A Correlation Study between the Scheme of Appraisal of Emotional Development (SAED) and Vineland Adaptive Behavior Scale (VABS)

    Science.gov (United States)

    La Malfa, Giampaolo; Lassi, Stefano; Bertelli, Marco; Albertini, Giorgio; Dosen, Anton

    2009-01-01

    The importance of emotional aspects in developing cognitive and social abilities has already been underlined by many authors even if there is no unanimous agreement on the factors constituting adaptive abilities, nor is there any on the way to measure them or on the relation between adaptive ability and cognitive level. The purposes of this study…

  15. Articles of protective clothing adapted for deflecting chemical permeation and methods therefor

    Science.gov (United States)

    Vo-Dinh, Tuan

    1996-01-01

    Apparatus and methods for detecting the permeation of hazardous or toxic chemicals through protective clothing are disclosed. The hazardous or toxic chemicals of interest do not possess the spectral characteristic of luminescence. The apparatus and methods utilize a spectrochemical modification technique to detect the luminescence quenching of an indicator compound which upon permeation of the chemical through the protective clothing, the indicator is exposed to the chemical, thus indicating chemical permeation.

  16. Risk and protective factors across multiple microsystems associated with internalizing symptoms and aggressive behavior in rural adolescents: Modeling longitudinal trajectories from the Rural Adaptation Project.

    Science.gov (United States)

    Smokowski, Paul R; Guo, Shenyang; Evans, Caroline B R; Wu, Qi; Rose, Roderick A; Bacallao, Martica; Cotter, Katie L

    2017-01-01

    The current study examined risk and protective factors across microsystems that impact the development of internalizing symptoms and aggression over 4 years in a sample of culturally diverse, rural adolescents. We explored whether risk and protective factors across microsystems were associated with changes in rates of internalizing symptoms and aggressive behavior. Data came from the Rural Adaptation Project (RAP), a 5-year longitudinal panel study of more than 4,000 students from 26 public middle schools and 12 public high schools. Three level HLM models were estimated to predict internalizing symptoms (e.g., depression, anxiety) and aggression. Compared with other students, risk for internalizing symptoms and aggression was elevated for youth exposed to risk factors in the form of school hassles, parent-child conflict, peer rejection, and delinquent friends. Microsystem protective factors in the form of ethnic identity, religious orientation, and school satisfaction decreased risk for aggression, but were not associated with internalizing symptoms, whereas future orientation and parent support decreased risk for internalizing symptoms, but not aggression. Results indicate that risks for internalizing symptoms and aggression are similar, but that unique protective factors are related to these adolescent behavioral health outcomes. Implications and limitations were discussed. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  17. Adaptive building envelopes, component development as well as implementation strategies

    Directory of Open Access Journals (Sweden)

    Tillmann Klein

    2015-11-01

    Full Text Available The papers in this issue of JFDE discuss the potential of adaptive building envelopes, component development as well as implementation strategies. The applied practice paper demonstrates decision strategies behind the adaptive sun shading system of the Al-Bahr Towers. Additivity in building envelopes is not only a strategy to fulfil the growing demands for energy efficient buildings and comfort but has great architectural implications as well. In general it asks for more complex components as well as control strategies. But complexity also means costs and risks, and we need to discuss the means and effects. This discussion in particular is very interesting because here science and practice meet. The Journal of Facade Design and Engineering JFDE will actively follow and stimulate by providing high quality contributions. Four of the paper contributions have their origins in the Conference ‘Facades 2014’, held in November 2014 in Lucerne. The contributions have been carefully selected and have been subjected to the regular double blind review process of the journal. We want to thank Prof. Dr. Andres Luible for the help in making this issue happen. We are proud that JFDE is the scientific partner for a number of conferences such as ‘The Future Envelope’ Conference on Building Envelopes held yearly in Delft (NL or Bath (UK, the ICAE International Congress on Architectural Envelopes in San Sebastian (ES and the above mentioned conference ‘Facades’ in Lucerne (CH and Detmold (D. Our latest partner is the ICBEST 2017 - International Conference on Building Envelope Systems and Technologies in Istanbul. The growing number of partners indicates the relevance of JFDE for our growing discipline and will assure the continuity of the journal. Facade Design and Engineering is a peer reviewed, open access journal, funded by The Netherlands Organisation for Scientific Research NWO (www.nwo.nl. We see ‘open access’ as the future publishing model

  18. Digital mountains: toward development and environment protection in mountain regions

    Science.gov (United States)

    Jiang, Xiaobo

    2007-06-01

    Former studies on mountain system are focused on the department or subject characters, i.e. different department and branches of learning carry out researches only for their individual purposes and with individual characters of the subject of interests. As a whole, their investigation is lacking of comprehensive study in combination with global environment. Ecological environment in mountain regions is vulnerable to the disturbance of human activities. Therefore, it is a key issue to coordinate economic development and environment protection in mountain regions. On the other hand, a lot of work is ongoing on mountain sciences, especially depending on the application of RS and GIS. Moreover, the development of the Digital Earth (DE) provides a clue to re-understand mountains. These are the background of the emergence of the Digital Mountains (DM). One of the purposes of the DM is integrating spatial related data and information about mountains. Moreover, the DM is a viewpoint and methodology of understanding and quantifying mountains holistically. The concept of the DM is that, the spatial and temporal data related to mountain regions are stored and managed in computers; moreover, manipulating, analyzing, modeling, simulating and sharing of the mountain information are implemented by utilizing technologies of RS, GIS, GPS, Geo-informatic Tupu, computer, virtual reality (VR), 3D simulation, massive storage, mutual operation and network communication. The DM aims at advancing mountain sciences and sustainable mountain development. The DM is used to providing information and method for coordinating the mountain regions development and environment protection. The fundamental work of the DM is the design of the scientific architecture. Furthermore, construct and develop massive databases of mountains are the important steps these days.

  19. Development of Protective Clothing against Nanoparticle Based on Electrospun Nanofibers

    Directory of Open Access Journals (Sweden)

    M. Faccini

    2012-01-01

    Full Text Available In this paper, the development of efficient protective clothing against nanoparticulate aerosols is presented. Nanofibrous mats of polyamide 6 (PA6 were deposited onto a nonwoven viscose substrate by electrospinning technique. The influence of electrospinning parameters, including solution concentration, viscosity, and conductivity, was studied for the production of nonwovens with controlled fiber diameter showing a size distribution ranging from 66 to 195 nm. By varying several process parameters, textiles with different thickness of the nanofiber layer and thus air permeability were obtained. A hot-press lamination process using a thermoplastic resin as glue was applied to improve the adhesion of the nanofiber layer onto the textile support. After 1500 cycles of repeated compression and torsion, the nanofiber layer was still firmly attached to the support, while mechanical damage is visible in some areas. The penetration of NaCl particles with diameter ranging from 15 to 300 nm through the electrospun textiles was found to be strongly dependent on nanofiber layer thickness. A really thin nanofiber coating provides up to 80% retention of 20 nm size particles and over 50% retention of 200 nm size nanoparticles. Increasing the thickness of the nanofiber mat, the filtration efficiency was increased to over 99% along the whole nanoparticle range. The results obtained highlight the potential of nanofibers in the development of efficient personal protective equipments against nanoparticles.

  20. Search for Astronomical Sites in Developing Countries and their Preventive Protection

    CERN Document Server

    Querci, F R

    2000-01-01

    The archives of meteorological satellites permit to find around the world dry sites well adapted to astronomical observations (in the visible, IR, and millimetric ranges), as a pre-selection of sites. The GSM (Grating Scale Monitor) technique permits to qualify some of them as astronomical sites for a future setting-up of astronomical observatories. Such sites are found in new astronomical countries or in Developing Countries. At the same time, their preventive protection from light pollution and/or radio interference has to be viewed. In practice, once the pre-selection is made, the government of these countries ought to be alerted for example by IAU and/or UN Office for Outer Space Affairs. The local site testing through GSM should be carried out in cooperation with astronomers or scientists of these countries under the umbrella of IAU. This should be an approach to help to introduce astronomy and astrophysics in Developing Countries.

  1. The Protective Effects of Adaptability, Study Skills, and Social Skills on Externalizing Student-Teacher Relationships

    Science.gov (United States)

    Fisher, Sycarah D.; Reynolds, Jennifer L.; Sheehan, Chelsea E.

    2016-01-01

    Although students with externalizing behaviors inherently exhibit behaviors that contribute to poor teacher relationships, little research has examined the positive characteristics these students may possess that serve to facilitate positive teacher relationships. This study explores the moderating effects of adaptability, social skills, and study…

  2. Development and evaluation of novel forecasting adaptive ensemble model

    Directory of Open Access Journals (Sweden)

    C.M. Anish

    2016-09-01

    Full Text Available This paper proposes a new ensemble based adaptive forecasting structure for efficient different interval days' ahead prediction of five different asset values (NAV. In this approach three individual adaptive structures such as adaptive moving average (AMA, adaptive auto regressive moving average (AARMA and feedback radial basis function network (FRBF are employed to first train with conventional LMS, conventional forward-backward LMS and corresponding learning algorithm of FRBF respectively. After successful validation of each model the output obtained by each individual model is optimally weighted using Genetic algorithm (GA as well as particle swarm optimization (PSO based techniques to produce the best possible different days ahead prediction accuracy. Finally the results of prediction obtained of the NAV values are compared with the results obtained by individual predictors as well as by other four existing ensemble schemes. It is in general demonstrated that in all cases the proposed forecasting scheme outperforms other competitive methods.

  3. Mechanisms of cell protection by adaptation to chronic and acute hypoxia: molecular biology and clinical practice.

    Science.gov (United States)

    Corbucci, G G; Marchi, A; Lettieri, B; Luongo, C

    2005-11-01

    Several experimental and clinical studies have shown that specific biochemical and molecular pathways are involved in the myocardial and skeletal muscle cell tolerance to acute and/or chronic hypoxic injury. A number of different factors were proposed to play a role in the preservation of tissue viability, but to a few of them a pivotal role in the adaptive mechanisms to hypoxic stimuli could be ascribed. Starting from the observation that mitochondrial electron transport chain (ETC) enzymic complexes are the targets of oxygen reduced availability, most of data are compatible with a mechanism of enzymic adaptation in which the nitric oxide (NO) generation plays the major role. If the partial and reversible NO-induced inhibition of ETC enzymic complexes represents the most rapid and prominent adaptive mechanism in counteracting the damaging effects of hypoxia, the sarcolemmal and mitochondrial K+(ATP) channels activation results to be closely involved in cytoprotection. This process is depending on protein kinase C (PKC) isoform activation triggered by reactive oxygen species (ROS) generation, adenosine triphosphate (ATP) depletion and Ca++ overload. It is well known that all these factors are present in hypoxia-induced oxidative damage and mitochondrial Ca++ altered pools represent powerful stimuli in the damaging processes. The activation of mitochondrial K+(ATP) channels leads to a significant reduction of Ca++ influx and attenuation of mitochondrial Ca++ overload. Closely linked to these adaptive changes signal transduction pathways are involved in the nuclear DNA damage and repair mechanisms. On this context, an essential role is played by the hypoxia-induced factor-1alpha (HIF-1alpha) in terms of key transcription factor involved in oxygen-dependent gene regulation. The knowledge of the biochemical and molecular sequences involved in these adaptive processes call for a re-evaluation of the therapeutic approach to hypoxia-induced pathologies. On this light

  4. Not a panacea: private sector engagement in adaptation and adaptation finance in developing countries

    NARCIS (Netherlands)

    Pauw, W.P.

    2015-01-01

    The role of the private sector in climate finance is increasingly emphasized in international political debates. Knowledge of private engagement in mitigating climate change and in more advanced economies is growing, but the evidence base for private-sector engagement in climate change adaptation in

  5. Not a panacea: private sector engagement in adaptation and adaptation finance in developing countries

    NARCIS (Netherlands)

    Pauw, W.P.

    2015-01-01

    The role of the private sector in climate finance is increasingly emphasized in international political debates. Knowledge of private engagement in mitigating climate change and in more advanced economies is growing, but the evidence base for private-sector engagement in climate change adaptation in

  6. The higher school teaching staff professional development system creation on the adaptive management principles

    Directory of Open Access Journals (Sweden)

    Borova T.A.

    2012-03-01

    Full Text Available The article deals with theoretical analysis of the higher school teaching staff professional development system creation on the adaptive management principles. It is determined the background and components of the higher school teaching staff professional development adaptive management system. It is specified the mechanisms for higher school teaching staff professional development adaptive management: monitoring and coaching. It is shown their place in the higher school teaching staff professional development system on the adaptive management principles. The results of the system efficiency are singled out.

  7. Is prevention of acute pesticide poisoning effective and efficient, with Locally Adapted Personal Protective Equipment? A randomized crossover study among farmers in Chitwan, Nepal

    DEFF Research Database (Denmark)

    Varma, Anshu; Neupane, Dinesh; Bonde, Jens Peter Ellekilde

    2016-01-01

    Background: Farmers' risk of pesticide poisoning can be reduced with personal protective equipment but in low-income countries farmers' use of such equipment is limited. Objective: To examine the effectiveness and efficiency of Locally Adapted Personal Protective Equipment to reduce organophospha...

  8. An adaptive control strategy of converter based DG to maintain protection coordination in distribution system

    DEFF Research Database (Denmark)

    Su, Chi; Liu, Zhou; Chen, Zhe

    2014-01-01

    Distributed generation (DG) is increasingly integrated into distribution systems due to its flexible onsite characteristic and low carbon emission. However, DG integration may change the fault current pattern in distribution systems, which may in turn degrade the performance and coordination...... of network protection devices. As a protection measure commonly used in distribution network, recloser-fuse coordination could suffer from this impact. Research work has been conducted to deal with this problem by modifying the control strategy of the DG converters during faults. These solutions generally...

  9. Microsystem design framework based on tool adaptations and library developments

    Science.gov (United States)

    Karam, Jean Michel; Courtois, Bernard; Rencz, Marta; Poppe, Andras; Szekely, Vladimir

    1996-09-01

    Besides foundry facilities, Computer-Aided Design (CAD) tools are also required to move microsystems from research prototypes to an industrial market. This paper describes a Computer-Aided-Design Framework for microsystems, based on selected existing software packages adapted and extended for microsystem technology, assembled with libraries where models are available in the form of standard cells described at different levels (symbolic, system/behavioral, layout). In microelectronics, CAD has already attained a highly sophisticated and professional level, where complete fabrication sequences are simulated and the device and system operation is completely tested before manufacturing. In comparison, the art of microsystem design and modelling is still in its infancy. However, at least for the numerical simulation of the operation of single microsystem components, such as mechanical resonators, thermo-elements, elastic diaphragms, reliable simulation tools are available. For the different engineering disciplines (like electronics, mechanics, optics, etc) a lot of CAD-tools for the design, simulation and verification of specific devices are available, but there is no CAD-environment within which we could perform a (micro-)system simulation due to the different nature of the devices. In general there are two different approaches to overcome this limitation: the first possibility would be to develop a new framework tailored for microsystem-engineering. The second approach, much more realistic, would be to use the existing CAD-tools which contain the most promising features, and to extend these tools so that they can be used for the simulation and verification of microsystems and of the devices involved. These tools are assembled with libraries in a microsystem design environment allowing a continuous design flow. The approach is driven by the wish to make microsystems accessible to a large community of people, including SMEs and non-specialized academic institutions.

  10. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development.

    Science.gov (United States)

    Berbée, Jimmy F P; Boon, Mariëtte R; Khedoe, P Padmini S J; Bartelt, Alexander; Schlein, Christian; Worthmann, Anna; Kooijman, Sander; Hoeke, Geerte; Mol, Isabel M; John, Clara; Jung, Caroline; Vazirpanah, Nadia; Brouwers, Linda P J; Gordts, Philip L S M; Esko, Jeffrey D; Hiemstra, Pieter S; Havekes, Louis M; Scheja, Ludger; Heeren, Joerg; Rensen, Patrick C N

    2015-03-10

    Brown adipose tissue (BAT) combusts high amounts of fatty acids, thereby lowering plasma triglyceride levels and reducing obesity. However, the precise role of BAT in plasma cholesterol metabolism and atherosclerosis development remains unclear. Here we show that BAT activation by β3-adrenergic receptor stimulation protects from atherosclerosis in hyperlipidemic APOE*3-Leiden.CETP mice, a well-established model for human-like lipoprotein metabolism that unlike hyperlipidemic Apoe(-/-) and Ldlr(-/-) mice expresses functional apoE and LDLR. BAT activation increases energy expenditure and decreases plasma triglyceride and cholesterol levels. Mechanistically, we demonstrate that BAT activation enhances the selective uptake of fatty acids from triglyceride-rich lipoproteins into BAT, subsequently accelerating the hepatic clearance of the cholesterol-enriched remnants. These effects depend on a functional hepatic apoE-LDLR clearance pathway as BAT activation in Apoe(-/-) and Ldlr(-/-) mice does not attenuate hypercholesterolaemia and atherosclerosis. We conclude that activation of BAT is a powerful therapeutic avenue to ameliorate hyperlipidaemia and protect from atherosclerosis.

  11. Multi-benefits of national parks and protected areas: an integrative approach for developing countries

    Directory of Open Access Journals (Sweden)

    Atiqul Haq Shah Md.

    2016-03-01

    Full Text Available National parks and protected areas can contribute significantly to the needs of poor people who live in and around them and depend heavily on forest resources for their subsistence. Especially for the rural poor who have limited economic options, use of national park resources are the main source for their survival, giving them direct benefits from food, medicine and forest products. National parks can contribute to maintaining the ecosystem and biodiversity conservation, along with the economic benefits to the local population. National parks and protected areas can play a significant role in climate change mitigation as well. Nevertheless, benefits from these areas are not well recognized in management especially in developing countries by incorporating them for climate change mitigation. Though usually more priority is given to conservation, improvement of livelihood and climate change mitigation can be achieved by integrating national parks into management and policy, and by consideration of the potential of human resources. Thus the integration can improve the poverty situation of local people and help them to adapt to climatic change mitigation strategies. Therefore, management of national parks and protected areas should ensure the participation of local communities and stakeholders.

  12. Economic performance of irrigation capacity development to adapt to climate in the American Southwest

    Science.gov (United States)

    Ward, Frank A.; Crawford, Terry L.

    2016-09-01

    additional storage, removal of constraints on weak transportation capacity, limited production scale, poor information access, weak risk-bearing capacity, limited management skills, scarce labor supply, low food processing capacity, and absolute scale constraints, all can raise the economic value of additional irrigation capacity development. Our results light a path forward to policy makers, water administrators, and farm managers, who bear the burden of protecting farm income, food and water security, and rural economic development in the world's dry regions faced by the need to adapt to climate variability.

  13. Flexible Thermal Protection System Development for Hypersonic Inflatable Aerodynamic Decelerators

    Science.gov (United States)

    DelCorso, Joseph A.; Bruce, Walter E., III; Hughes, Stephen J.; Dec, John A.; Rezin, Marc D.; Meador, Mary Ann B.; Guo, Haiquan; Fletcher, Douglas G.; Calomino, Anthony M.; Cheatwood, McNeil

    2012-01-01

    The Hypersonic Inflatable Aerodynamic Decelerators (HIAD) project has invested in development of multiple thermal protection system (TPS) candidates to be used in inflatable, high downmass, technology flight projects. Flexible TPS is one element of the HIAD project which is tasked with the research and development of the technology ranging from direct ground tests, modelling and simulation, characterization of TPS systems, manufacturing and handling, and standards and policy definition. The intent of flexible TPS is to enable large deployable aeroshell technologies, which increase the drag performance while significantly reducing the ballistic coefficient of high-mass entry vehicles. A HIAD requires a flexible TPS capable of surviving aerothermal loads, and durable enough to survive the rigors of construction, handling, high density packing, long duration exposure to extrinsic, in-situ environments, and deployment. This paper provides a comprehensive overview of key work being performed within the Flexible TPS element of the HIAD project. Included in this paper is an overview of, and results from, each Flexible TPS research and development activity, which includes ground testing, physics-based thermal modelling, age testing, margins policy, catalysis, materials characterization, and recent developments with new TPS materials.

  14. Vegetation as self-adaptive coastal protection: Reduction of current velocity and morphologic plasticity of a brackish marsh pioneer.

    Science.gov (United States)

    Carus, Jana; Paul, Maike; Schröder, Boris

    2016-03-01

    By reducing current velocity, tidal marsh vegetation can diminish storm surges and storm waves. Conversely, currents often exert high mechanical stresses onto the plants and hence affect vegetation structure and plant characteristics. In our study, we aim at analysing this interaction from both angles. On the one hand, we quantify the reduction of current velocity by Bolboschoenus maritimus, and on the other hand, we identify functional traits of B. maritimus' ramets along environmental gradients. Our results show that tidal marsh vegetation is able to buffer a large proportion of the flow velocity at currents under normal conditions. Cross-shore current velocity decreased with distance from the marsh edge and was reduced by more than 50% after 15 m of vegetation. We were furthermore able to show that plants growing at the marsh edge had a significantly larger diameter than plants from inside the vegetation. We found a positive correlation between plant thickness and cross-shore current which could provide an adaptive value in habitats with high mechanical stress. With the adapted morphology of plants growing at the highly exposed marsh edge, the entire vegetation belt is able to better resist the mechanical stress of high current velocities. This self-adaptive effect thus increases the ability of B. maritimus to grow and persist in the pioneer zone and may hence better contribute to ecosystem-based coastal protection by reducing current velocity.

  15. Perceptions of Australian marine protected area managers regarding the role, importance, and achievability of adaptation for managing the risks of climate change

    Directory of Open Access Journals (Sweden)

    Christopher Cvitanovic

    2014-12-01

    Full Text Available The rapid development of adaptation as a mainstream strategy for managing the risks of climate change has led to the emergence of a broad range of adaptation policies and management strategies globally. However, the success of such policies or management interventions depends on the effective integration of new scientific research into the decision-making process. Ineffective communication between scientists and environmental decision makers represents one of the key barriers limiting the integration of science into the decision-making process in many areas of natural resource management. This can be overcome by understanding the perceptions of end users, so as to identify knowledge gaps and develop improved and targeted strategies for communication and engagement. We assessed what one group of environmental decision makers, Australian marine protected area (MPA managers, viewed as the major risks associated with climate change, and their perceptions regarding the role, importance, and achievability of adaptation for managing these risks. We also assessed what these managers perceived as the role of science in managing the risks from climate change, and identified the factors that increased their trust in scientific information. We do so by quantitatively surveying 30 MPA managers across 3 Australian management agencies. We found that although MPA managers have a very strong awareness of the range and severity of risks posed by climate change, their understanding of adaptation as an option for managing these risks is less comprehensive. We also found that although MPA managers view science as a critical source of information for informing the decision-making process, it should be considered in context with other knowledge types such as community and cultural knowledge, and be impartial, evidence based, and pragmatic in outlining policy and management recommendations that are realistically achievable.

  16. MEASURING VALUES FOR WETLANDS PROTECTION IN A DEVELOPING COUNTRY FROM DOMESTIC AND INTERNATIONAL CITIZEN GROUPS

    OpenAIRE

    Allen, James C.; Bergstrom, John C.

    2003-01-01

    Because of pressures to convert natural areas to commercial economic development uses, protecting natural areas in developing countries is a major challenge. A developing country may desire to protect natural areas, but relatively high out-of-pocket and opportunity costs of protection may pose considerable hurdles. To help protect natural areas in a developing country, the international community often gets involved; for example, providing funds to purchase and preserve natural areas such as ...

  17. Modelling Local Attitudes to Protected Areas in Developing Countries

    Directory of Open Access Journals (Sweden)

    Chiara Bragagnolo

    2016-01-01

    Full Text Available During a time of intensifying competition for land, Protected Areas (PAs are coming under increasing pressure to justify their status. Positive local attitudes to a PA are a potentially important component of any such justification, especially in the developing world where human pressure on natural resources is often high. However, despite numerous studies our understanding of what drives positive attitudes to PAs is still exceedingly limited. Here, we review the literature on local attitudes towards PAs in developing countries. Our survey reveals a highly fragmented research area where studies typically lack an explicit conceptual basis, and where there is wide variation in choice of statistical approach, explanatory and response variables, and incorporation of contextual information. Nevertheless, there is a relatively high degree of concordance between studies, with certain variables showing strong associations with attitudes. We recommend that PA attitude researchers in developing countries adopt a more rigorous model building approach based on a clear conceptual framework and drawing on the extensive empirical literature. Such an approach would improve the quality of research, increase comparability, and provide a stronger basis to support conservation decision-making.

  18. Uncovering Mechanisms for Repair and Protection in Cold Environments Through Studies of Cold Adapted Archaea

    Science.gov (United States)

    2009-12-18

    Contract Number: FA9550-07-1-0085 Rick Cavicchioli, Tim Williams, Oliver Pilak University of New South Wales, Sydney, Australia Introduction...adapted microorganism . Objective 1: Progress All three chaperonin genes from M. burtonii have been cloned and the gene products have been...2ºC, 1ºC, 4ºC, 10ºC, 16ºC, 23ºC, 28ºC), which encompasses the lower to upper growth limits of M. burtonii. We also examined the effect of

  19. Developing Adaptive Expertise with Pasifika Learners in an Inquiry Classroom

    Science.gov (United States)

    Thompson, Zain; Hunter, Jodie

    2015-01-01

    In the current reform of mathematics classrooms teachers are charged with the role of facilitating collaborative groups during problem-solving activity. The challenge is for teachers to engage students in making mathematical meaning during collaborative group discussions. In this paper we draw on the concept of adaptive expertise to report on…

  20. Computerized adaptive testing for measuring development of young children

    NARCIS (Netherlands)

    Jacobusse, G.; Buuren, S. van

    2007-01-01

    Developmental indicators that are used for routine measurement in The Netherlands are usually chosen to optimally identify delayed children. Measurements on the majority of children without problems are therefore quite imprecise. This study explores the use of computerized adaptive testing (CAT) to

  1. Identifying product development crises: The potential of adaptive heuristics

    DEFF Research Database (Denmark)

    Münzberger, C.; Stingl, Verena; Oehmen, Josef

    of a project crisis is often difficult. Yet, to allow fast crisis response, timely identification is critical for successful crisis management. Adaptive heuristics are judgement strategies that can strive in circumstances of limited and ambiguous information. This article presents a theoretical proposition...

  2. Career Adaptability Development in Adolescence: Multiple Predictors and Effect on Sense of Power and Life Satisfaction

    Science.gov (United States)

    Hirschi, Andreas

    2009-01-01

    This longitudinal panel study investigated predictors of career adaptability development and its effect on development of sense of power and experience of life satisfaction among 330 Swiss eighth graders. A multivariate measure of career adaptability consisting of career choice readiness, planning, exploration, and confidence was applied. Based on…

  3. Career Adaptability Development in Adolescence: Multiple Predictors and Effect on Sense of Power and Life Satisfaction

    Science.gov (United States)

    Hirschi, Andreas

    2009-01-01

    This longitudinal panel study investigated predictors of career adaptability development and its effect on development of sense of power and experience of life satisfaction among 330 Swiss eighth graders. A multivariate measure of career adaptability consisting of career choice readiness, planning, exploration, and confidence was applied. Based on…

  4. Adaptation to osmotic stress provides protection against ammonium nitrate in Pelophylax perezi embryos

    Energy Technology Data Exchange (ETDEWEB)

    Ortiz-Santaliestra, Manuel E., E-mail: ortizsantali@wisc.ed [Department of Animal Biology, University of Salamanca, Campus Miguel de Unamuno, 37007 Salamanca (Spain); Fernandez-Beneitez, Maria Jose, E-mail: may_beneitez@yahoo.e [Department of Animal Biology, University of Salamanca, Campus Miguel de Unamuno, 37007 Salamanca (Spain); Lizana, Miguel, E-mail: lizana@usal.e [Department of Animal Biology, University of Salamanca, Campus Miguel de Unamuno, 37007 Salamanca (Spain); Marco, Adolfo, E-mail: amarco@ebd.csic.e [Donana Biological Station, Spanish Council for Scientific Research, C/Americo Vespucio s/n, 41092 Sevilla (Spain)

    2010-03-15

    The negative effects of pollution on amphibians are especially high when animals are additionally stressed by other environmental factors such as water salinity. However, the stress provoked by salinity may vary among populations because of adaptation processes. We tested the combined effect of a common fertilizer, ammonium nitrate (0-90.3 mg N-NO{sub 3}NH{sub 4}/L), and water salinity (0-2 per mille ) on embryos of two Pelophylax perezi populations from ponds with different salinity concentrations. Embryos exposed to the fertilizer were up to 17% smaller than controls. Survival rates of embryos exposed to a single stressor were always below 10%. The exposure to both stressors concurrently increased mortality rate (>95%) of embryos from freshwater. Since the fertilizer was lethal only when individuals were stressed by the salinity, it did not cause lethal effects on embryos naturally adapted to saline environments. Our results underscore the importance of testing multiple stressors when analyzing amphibian sensitivity to environmental pollution. - Natural resistance to salinity minimizes the impact of chemical fertilizers on amphibian embryos.

  5. Economic development and environmental protection: an ecological economics perspective.

    Science.gov (United States)

    Rees, William E

    2003-01-01

    This paper argues on both theoretical and empirical grounds that, beyond a certain point, there is an unavoidable conflict between economic development (generally taken to mean 'material economic growth') and environmental protection. Think for a moment of natural forests, grasslands, marine estuaries, salt marshes, and coral reefs; and of arable soils, aquifers, mineral deposits, petroleum, and coal. These are all forms of 'natural capital' that represent highly-ordered self-producing ecosystems or rich accumulations of energy/matter with high use potential (low entropy). Now contemplate despoiled landscapes, eroding farmlands, depleted fisheries, anthropogenic greenhouse gases, acid rain, poisonous mine tailings and toxic synthetic compounds. These all represent disordered systems or degraded forms of energy and matter with little use potential (high entropy). The main thing connecting these two states is human economic activity. Ecological economics interprets the environment-economy relationship in terms of the second law of thermodynamics. The second law sees economic activity as a dissipative process. From this perspective, the production of economic goods and services invariably requires the consumption of available energy and matter. To grow and develop, the economy necessarily 'feeds' on sources of high-quality energy/matter first produced by nature. This tends to disorder and homogenize the ecosphere, The ascendance of humankind has consistently been accompanied by an accelerating rate of ecological degradation, particularly biodiversity loss, the simplification of natural systems and pollution. In short, contemporary political rhetoric to the contrary, the prevailing growth-oriented global development paradigm is fundamentally incompatible with long-term ecological and social sustainability. Unsustainability is not a technical nor economic problem as usually conceived, but rather a state of systemic incompatibility between a economy that is a fully

  6. A new development for determining the ultraviolet protection factor

    OpenAIRE

    Campos Payá, Juan; DÍAZ-GARCÍA Pablo; Montava Seguí, Ignacio José; Miró Martínez, Pau; Bonet Aracil, María Angeles

    2016-01-01

    Ultraviolet radiation has become an increasing problem in recent years. It causes many injuries in humans giving rise to the need for protection against ultraviolet radiation, which can be provided by textiles with a high ultraviolet protection factor. This factor can be determined by a variety of established methods. This work focuses on establishing a new methodology for determining the ultraviolet protection factor value using an ultraviolet lamp and a detector. The fabric is to be tested ...

  7. INTUITEL and the Hypercube Model - Developing Adaptive Learning Environments

    Directory of Open Access Journals (Sweden)

    Kevin Fuchs

    2016-06-01

    Full Text Available In this paper we introduce an approach for the creation of adaptive learning environments that give human-like recommendations to a learner in the form of a virtual tutor. We use ontologies defining pedagogical, didactic and learner-specific data describing a learner's progress, learning history, capabilities and the learner's current state within the learning environment. Learning recommendations are based on a reasoning process on these ontologies and can be provided in real-time. The ontologies may describe learning content from any domain of knowledge. Furthermore, we describe an approach to store learning histories as spatio-temporal trajectories and to correlate them with influencing didactic factors. We show how such analysis of spatiotemporal data can be used for learning analytics to improve future adaptive learning environments.

  8. Using Uncertain Climate and Development Information in Health Adaptation Planning.

    Science.gov (United States)

    Ebi, Kristie L; Hess, Jeremy J; Isaksen, Tania Busch

    2016-03-01

    To aid health adaptation decision-making, there are increasing efforts to provide climate projections at finer temporal and spatial scales. Relying solely on projected climate changes for longer-term decisions makes the implicit assumption that sources of vulnerability other than climate change will remain the same, which is not very probable. Over longer time horizons, this approach likely over estimates the extent to which climate change could alter the magnitude and pattern of health outcomes, introducing systematic bias into health management decisions. To balance this potential bias, decision-makers also need projections of other drivers of health outcomes that are, like climate change, recognized determinants of some disease burdens. Incorporating projections via an iterative process that allows for regular updates based on new knowledge and experience has the potential to improve the utility of fine-scale climate projections in health system adaptation to climate change.

  9. CDP - Adaptive Supervisory Control and Data Acquisition (SCADA) Technology for Infrastructure Protection

    Energy Technology Data Exchange (ETDEWEB)

    Marco Carvalho; Richard Ford

    2012-05-14

    Supervisory Control and Data Acquisition (SCADA) Systems are a type of Industrial Control System characterized by the centralized (or hierarchical) monitoring and control of geographically dispersed assets. SCADA systems combine acquisition and network components to provide data gathering, transmission, and visualization for centralized monitoring and control. However these integrated capabilities, especially when built over legacy systems and protocols, generally result in vulnerabilities that can be exploited by attackers, with potentially disastrous consequences. Our research project proposal was to investigate new approaches for secure and survivable SCADA systems. In particular, we were interested in the resilience and adaptability of large-scale mission-critical monitoring and control infrastructures. Our research proposal was divided in two main tasks. The first task was centered on the design and investigation of algorithms for survivable SCADA systems and a prototype framework demonstration. The second task was centered on the characterization and demonstration of the proposed approach in illustrative scenarios (simulated or emulated).

  10. PHG: A Toolbox for Developing Parallel Adaptive Finite Element Programs

    Institute of Scientific and Technical Information of China (English)

    ZHANG Linbo

    2011-01-01

    @@ Significance of the finite element method The finite element method (Feng, 1965) is mainly used for numerical solution of partial differential equations.It consists of partitioning the computational domain into a mesh composed of disjoint smaller sub-domains called elements which cover the whole domain, and approximating the solution in each element using simple functions (usually polynomials) so that the original problem can be turned into a suitable one to be solved on modern computers.The finite element method has a very wide range of applications as one of the most important methods in scientific and engineering computing.In the finite element method, two key factors which can affect the computational efficiency and precision of the computed solution are quality and distribution of the mesh elements.The adaptive finite element method, first proposed by I.Babuska and W.Rheinboldt in 1978 (Babuska et al., 1978), automatically adjusts and optimizes the distribution of mesh elements according to estimation on the distribution of the error of the computed solution, in order to improve the precision of the computed solution.Recent researches show that for many problems with locally singular solutions, by using mathematically rigorous a posteriori error estimates and suitable adaptive strategy, the adaptive finite element method can produce quasi-optimal meshes and dramatically improve the overall computational efficiency.

  11. Facilitating climate change adaptation through communication: Insights from the development of a visualization tool

    DEFF Research Database (Denmark)

    Glaas, Erik; Ballantyne, Anne Gammelgaard; Neset, Tina

    2015-01-01

    Climate change communication on anticipated impacts and adaptive responses is frequently presented as an effective means to facilitate implementation of adaptation to mitigate risks to residential buildings. However, it requires that communication is developed in a way that resonates...... with the context of the target audience, provides intelligible information and addresses perceived barriers to adaptation. In this paper we reflect upon criteria for useful climate change communication gained over a three year development process of a web-based tool - VisAdaptTM – aimed at increasing the adaptive...... capacity among Nordic homeowners. Based on the results from continuous user-testing and focus group interviews we outline lessons learned and key aspects to consider in the design of tools for communicating complex issues such as climate change effects and adaptive response measures....

  12. Hanford Site Protective Barrier Development Program: Fiscal year 1990 highlights

    Energy Technology Data Exchange (ETDEWEB)

    Cadwell, L.L. (ed.)

    1991-09-01

    The Hanford Site Protective Barrier Development Program was jointly developed by Pacific Northwest Laboratory (PNL) and Westinghouse Hanford Company (WHC) to design and test an earthen cover system(s) that can be used to inhibit water infiltration; plant, animal, and human intrusion; and wind and water erosion. The joint PNL/WHC program was initiated in FY 1986. To date, research findings support the initial concepts of barrier designs for the Hanford Site. A fine-soil surface is planned to partition surface water into runoff and temporary storage. Transpiration by vegetation that grows in the fine-soil layer will return stored water to the atmosphere as will surface evaporation. A capillary break created by the interface of the fine-soil layer and coarser textured materials below will further limit the downward migration of surface water, making it available over a longer period of time for cycling to the atmosphere. Should water pass the interface, it will drain laterally through a coarse textured sand/gravel layer. Tested barrier designs appear to work adequately to prevent drainage under current and postulated wetter-climate (added precipitation) conditions. Wind and water erosion tasks are developing data to predict the extent of erosion on barrier surfaces. Data collected during the last year confirm the effectiveness of small burrowing animals in removing surface water. Water infiltrating through burrows of larger mammals was subsequently lost by natural processes. Natural analog and climate change studies are under way to provide credibility for modeling the performance of barrier designs over a long period of time and under shifts in climate. 10 refs., 30 figs.

  13. Declining human population but increasing residential development around protected areas in Puerto Rico

    Science.gov (United States)

    J. Castro-Prieto; S. Martinuzzi; V.C. Radeloff; D.P. Helmers; M. Quiñones; W.A. Gould

    2017-01-01

    Increasing residential development around protected areas is a major threat for protected areas worldwide, and human population growth is often the most important cause. However, population is decreasing in many regions as a result of socio-economic changes, and it is unclear how residential development around protected areas is affected in these situations. We...

  14. An adaptive FEC to protect RoHC and UDP-Lite H.264 video critical data

    Institute of Scientific and Technical Information of China (English)

    CHEN Zhi-kui

    2006-01-01

    This paper describes how to use an Adaptive Forward Error Correction (AFEC) algorithm to efficiently protect the critical data areas of compressed headers and UDP-Lite packets for data transport in a radio link layer of a wireless connection.Augmented with RoHC and UDP-Lite, for H.264 video transmissions over wireless channels in a heterogeneous wired-wireless environment, the erroneous packet payloads can be useful and better able to cope with lost packets (native UDP case), by adopting some of the erasure and error resilient modes in H.264. The context transfer during inter/intra handover is also discussed. Simulations demonstrated that the proposed scenario significantly improves the PSNR performance and video quality.

  15. Development and testing of a flexible ballistic neck protection

    NARCIS (Netherlands)

    Roebroeks, G.H.J.J.; Rensink, P.

    2016-01-01

    Sufficient ballistic protection of the neck area would significantly reduce the vulnerability of an infantry soldier. So far this protection is offered by extensions on the ballistic vest or combat helmet. However, the requirements for head agility and the various body to head positions combined wit

  16. Development and testing of a flexible ballistic neck protection

    NARCIS (Netherlands)

    Roebroeks, G.H.J.J.; Rensink, P.

    2016-01-01

    Sufficient ballistic protection of the neck area would significantly reduce the vulnerability of an infantry soldier. So far this protection is offered by extensions on the ballistic vest or combat helmet. However, the requirements for head agility and the various body to head positions combined

  17. Metallic Thermal Protection System Technology Development: Concepts, Requirements and Assessment Overview

    Science.gov (United States)

    Dorsey, John T.; Poteet, Carl C.; Chen, Roger R.; Wurster, Kathryn E.

    2002-01-01

    A technology development program was conducted to evolve an earlier metallic thermal protection system (TPS) panel design, with the goals of: improving operations features, increasing adaptability (ease of attaching to a variety of tank shapes and structural concepts), and reducing weight. The resulting Adaptable Robust Metallic Operable Reusable (ARMOR) TPS system incorporates a high degree of design flexibility (allowing weight and operability to be traded and balanced) and can also be easily integrated with a large variety of tank shapes, airframe structural arrangements and airframe structure/material concepts. An initial attempt has been made to establish a set of performance based TPS design requirements. A set of general (FARtype) requirements have been proposed, focusing on defining categories that must be included for a comprehensive design. Load cases required for TPS design must reflect the full flight envelope, including a comprehensive set of limit loads, However, including additional loads. such as ascent abort trajectories, as ultimate load cases, and on-orbit debris/micro-meteoroid hypervelocity impact, as one of the discrete -source -damage load cases, will have a significant impact on system design and resulting performance, reliability and operability. Although these load cases have not been established, they are of paramount importance for reusable vehicles, and until properly included, all sizing results and assessments of reliability and operability must be considered optimistic at a minimum.

  18. Branched Fatty Acid Esters of Hydroxy Fatty Acids (FAHFAs) Protect against Colitis by Regulating Gut Innate and Adaptive Immune Responses.

    Science.gov (United States)

    Lee, Jennifer; Moraes-Vieira, Pedro M; Castoldi, Angela; Aryal, Pratik; Yee, Eric U; Vickers, Christopher; Parnas, Oren; Donaldson, Cynthia J; Saghatelian, Alan; Kahn, Barbara B

    2016-10-14

    We recently discovered a structurally novel class of endogenous lipids, branched palmitic acid esters of hydroxy stearic acids (PAHSAs), with beneficial metabolic and anti-inflammatory effects. We tested whether PAHSAs protect against colitis, which is a chronic inflammatory disease driven predominantly by defects in the innate mucosal barrier and adaptive immune system. There is an unmet clinical need for safe and well tolerated oral therapeutics with direct anti-inflammatory effects. Wild-type mice were pretreated orally with vehicle or 5-PAHSA (10 mg/kg) and 9-PAHSA (5 mg/kg) once daily for 3 days, followed by 10 days of either 0% or 2% dextran sulfate sodium water with continued vehicle or PAHSA treatment. The colon was collected for histopathology, gene expression, and flow cytometry. Intestinal crypt fractions were prepared for ex vivo bactericidal assays. Bone marrow-derived dendritic cells pretreated with vehicle or PAHSA and splenic CD4(+) T cells from syngeneic mice were co-cultured to assess antigen presentation and T cell activation in response to LPS. PAHSA treatment prevented weight loss, improved colitis scores (stool consistency, hematochezia, and mouse appearance), and augmented intestinal crypt Paneth cell bactericidal potency via a mechanism that may involve GPR120. In vitro, PAHSAs attenuated dendritic cell activation and subsequent T cell proliferation and Th1 polarization. The anti-inflammatory effects of PAHSAs in vivo resulted in reduced colonic T cell activation and pro-inflammatory cytokine and chemokine expression. These anti-inflammatory effects appear to be partially GPR120-dependent. We conclude that PAHSA treatment regulates innate and adaptive immune responses to prevent mucosal damage and protect against colitis. Thus, PAHSAs may be a novel treatment for colitis and related inflammation-driven diseases. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  19. An Adaptive Watermarking Technique for the copyright of digital images and Digital Image Protection

    CERN Document Server

    Perwej, Yusuf; Perwej, Asif; 10.5121/ijma.2012.4202

    2012-01-01

    The Internet as a whole does not use secure links, thus information in transit may be vulnerable to interruption as well. The important of reducing a chance of the information being detected during the transmission is being an issue in the real world now days. The Digital watermarking method provides for the quick and inexpensive distribution of digital information over the Internet. This method provides new ways of ensuring the sufficient protection of copyright holders in the intellectual property dispersion process. The property of digital watermarking images allows insertion of additional data in the image without altering the value of the image.In this paper investigate the following relevant concepts and terminology, history of watermarks and the properties of a watermarking system and applications. We are proposing edge detection using Gabor Filters. In this paper we are proposed least significant bit (LSB) substitution method to encrypt the message in the watermark image file. The benefits of the LSB ...

  20. Protected Areas' Impacts on Brazilian Amazon Deforestation: Examining Conservation-Development Interactions to Inform Planning

    National Research Council Canada - National Science Library

    Pfaff, Alexander; Robalino, Juan; Herrera, Diego; Sandoval, Catalina

    2015-01-01

    .... For Brazil's Legal Amazon, we estimate the average impact of protection upon deforestation and show how protected areas' forest impacts vary significantly with development pressure. We use matching, i.e...

  1. Protected Areas' Impacts on Brazilian Amazon Deforestation: Examining Conservation - Development Interactions to Inform Planning: e0129460

    National Research Council Canada - National Science Library

    Alexander Pfaff; Juan Robalino; Diego Herrera; Catalina Sandoval

    2015-01-01

    .... For Brazil's Legal Amazon, we estimate the average impact of protection upon deforestation and show how protected areas' forest impacts vary significantly with development pressure. We use matching, i.e...

  2. Adaptive Vocational Personality Questionnaire Development and Validation of an adaptive personality questionnaire to analyze the vocational behavior of university students

    Directory of Open Access Journals (Sweden)

    Amparo Gómez-Artiga

    2013-05-01

    Full Text Available This study presents a personality evaluation instrument adapted to the vocational setting: the Adaptive Vocational Personality Questionnaire (AVPQ. The questionnaire was developed and tested in a sample of 2160 university students in the final years of their degree programs. The purpose of the study is to validate the questionnaire, providing evidence about its internal structure and its usefulness for predicting scores on a criterion scale. A confirmatory factor analysis combined with a cross-validation design was used: the exploratory sample (n = 879 helped to identify the model with the factorial structure that best fit the relations among the items. As expected, this model had two related but clearly separate factors: Adaptive Personality Characteristics (AC with 9 items and Non-Adaptive Personality Characteristics (NAC with 11 items. The validation sample (n =932 was used to test the generalization capacity of this model, which was satisfactory and showed a good reliability index. Regarding its usefulness in predicting proactive job-search behaviors, the results were also satisfactory. The questionnaire and keys are provided, as well as the criteria for calculating the scores on each scale and on the entire questionnaire.

  3. Challenges and Opportunities to Climate Change Adaptation and Sustainable Development Among Tanzanian Rural Communities Challenges and Opportunities to Climate Change Adaptation and Sustainable Development Among Tanzanian Rural Communities

    Directory of Open Access Journals (Sweden)

    Esther W. Dungumaro

    2010-12-01

    Full Text Available In more recent years climate change impacts have been obvious around the globe. This non-contentious reality has resulted in various global initiatives to reduce climate change impacts. However, differences exist in opportunities and capacity to adaptation. This paper, descriptive in nature, draws heavily from literature and also uses 2002 Tanzanian population and housing census to identify and discuss major challenges and opportunities to climate change adaptation and sustainable development in rural areas of Tanzania. Two groups are of focus; pastoralist herders and smallholder farmers. Analysis indicates that opportunities to climate change adaptation among rural community include their knowledge and experience. Challenges are centered on the pervasive poverty, rapid population increase and high illiteracy rates. Forces beyond their control including funds and governance also present definite limits to climate change adaptation. The paper suggests among others, the effective implementation of two top policies: education and social security funding.In more recent years climate change impacts have been obvious around the globe. This non-contentious reality has resulted in various global initiatives to reduce climate change impacts. However, differences exist in opportunities and capacity to adaptation. This paper, descriptive in nature, draws heavily from literature and also uses 2002 Tanzanian population and housing census to identify and discuss major challenges and opportunities to climate change adaptation and sustainable development in rural areas of Tanzania. Two groups are of focus; pastoralist herders and smallholder farmers. Analysis indicates that opportunities to climate change adaptation among rural community include their knowledge and experience. Challenges are centered on the pervasive poverty, rapid population increase and high illiteracy rates. Forces beyond their control including funds and governance also present definite

  4. Development of adaptation strategies of marshland water management to regional climate change

    Science.gov (United States)

    Bormann, Helge; Frank, Ahlhorn; Luise, Giani; Kirsten, Klaassen; Thomas, Klenke

    2010-05-01

    Since many centuries, low lying areas at the German North Sea coast are intensively managed by water boards and dike boards. Sophisticated water management systems have been developed in order to keep the water out of the low lying areas in wet periods, while in some regions additional water is needed in dry periods for agricultural and ecological purposes. For example in the Wesermarsch region, a water management system has been developed in historical times, draining the landscape in winter time by means of channels, ditches, gates, sluices and pumping stations. In contrast, in summer time water is conducted from Weser River into the Wesermarsch region to serve watering of animals, fencing grazing areas and ensuring a continuous flow in the marsh watercourses. Doing so, maintaining soil fertility is guaranteed for agriculture as well as protection against floods, sustaining river ecology and traditional livestock farming. Due to climate variability and river engineering, the water management of the Wesermarsch already runs into problems because watering in summer cannot be assured any longer in sufficient water quality. During high tides, salt water from the North Sea is flowing upstream into the Weser estuary, generating brackish conditions in the lower Weser River. In addition, soil subsidence and soil mineralization of marsh and peat soils as well as the sea level rise increase the necessary pumping frequency and the emerging energy costs. The expected future climate change will further aggravate those problems and require an adaptation of the current management system. This presentation introduces the concept behind and preliminary results of an integrative and participatory project, aiming at the development of a new water management strategy adapted to the regional climate change likely to occur until year 2050. In close cooperation with a number of regional stakeholders and based on the priorities with respect to the future development of the region

  5. Design and development of adapters for electromagnetic trackers to perform navigated laparoscopic radiofrequency ablation

    Directory of Open Access Journals (Sweden)

    Schweikard Achim

    2007-10-01

    Full Text Available Abstract Background Laparoscopic radiofrequency ablation (RFA is an accepted approach to treat unresectable liver tumours distinguishing itself from other techniques by combining minimal invasiveness and the advantages of a surgical approach. The major task of laparoscopic RFA is the accurate needle placement to achieve complete tumour ablation. The use of an ultrasound-based, laparoscopic online-navigation system could increase the safety and accuracy of punctures. To connect such a system with the laparoscopic ultrasound (LUS transducer or the RFA needle especially designed adapters are needed. In this article we present our first experiences and prototypes for different sterilizable adapters for an electromagnetic navigation system for laparoscopic RFA. Methods All adapters were constructed with the help of a standard 3D CAD software. The adapters were built from medical stainless steel alloys and polyetherketone (PEEK. Prototypes were built in aluminium and polyoxymethilen (POM. We have designed and developed several adapters for the connection of electromagnetical tracking systems with different RFA needles and a laparoscopic ultrasound transducers. Results Based on earlier experiences of the initial version of the adapter, sterilisable adapters have been developed using biocompatible materials only. After short introduction, the adapters could be mounted to the laparoscopic ultrasound probe and the RFA needle under sterile conditions without any difficulties. Laboratory tests showed no disturbance of laparoscopic navigation system by the adapters. Anatomic landmarks in the liver could be safely reached. The adapters showed good feasibility, ergonomics, sterilizability and stability. Conclusion The development of usable adapters is the prerequisite for accurate tracking of a RFA needle for laparoscopic navigation purposes as well as 3D navigated ultrasound data acquisition. We designed, tested and used different adapters for the use of a

  6. Measuring and tracking the flow of climate change adaptation aid to the developing world

    Science.gov (United States)

    Donner, Simon D.; Kandlikar, Milind; Webber, Sophie

    2016-05-01

    The developed world has pledged to mobilize at least US 100 billion per year of ‘new’ and ‘additional’ funds by 2020 to help the developing world respond to climate change. Tracking this finance is particularly problematic for climate change adaptation, as there is no clear definition of what separates adaptation aid from standard development aid. Here we use a historical database of overseas development assistance projects to test the effect of different accounting assumptions on the delivery of adaptation finance to the developing countries of Oceania, using machine algorithms developed from a manual pilot study. The results show that explicit adaptation finance grew to 3%-4% of all development aid to Oceania by the 2008-2012 period, but that total adaptation finance could be as high as 37% of all aid, depending on potentially politically motivated assumptions about what counts as adaptation. There was also an uneven distribution of adaptation aid between countries facing similar challenges like Kiribati, the Marshall Islands, and the Federated States of Micronesia. The analysis indicates that data allowing individual projects to be weighted by their climate change relevance is needed. A robust and mandatory metadata system for all aid projects would allow multilateral aid agencies and independent third parties to perform their own analyses using different assumptions and definitions, and serve as a key check on international climate aid promises.

  7. The political economy of urban climate adaptation and development planning in Surat, India

    NARCIS (Netherlands)

    E. Chu

    2015-01-01

    This paper argues for a political economic approach to understanding climate change adaptation and development planning in an urban context. Based on field research conducted in Surat, India, across a period of two years, I illustrate how climate adaptation is rooted in preexisting and contextually

  8. An Adaptive Approach to Managing Knowledge Development in a Project-Based Learning Environment

    Science.gov (United States)

    Tilchin, Oleg; Kittany, Mohamed

    2016-01-01

    In this paper we propose an adaptive approach to managing the development of students' knowledge in the comprehensive project-based learning (PBL) environment. Subject study is realized by two-stage PBL. It shapes adaptive knowledge management (KM) process and promotes the correct balance between personalized and collaborative learning. The…

  9. Developing adaptive user interfaces using a game-based simulation environment

    NARCIS (Netherlands)

    Brake, G.M. te; Greef, T.E. de; Lindenberg, J.; Rypkema, J.A.; Smets-Noor, N.J.J.M.

    2006-01-01

    In dynamic settings, user interfaces can provide more optimal support if they adapt to the context of use. Providing adaptive user interfaces to first responders may therefore be fruitful. A cognitive engineering method that incorporates development iterations in both a simulated and a real-world en

  10. Towards Individualized Online Learning: The Design and Development of an Adaptive Web Based Learning Environment

    Science.gov (United States)

    Inan, Fethi A.; Flores, Raymond; Ari, Fatih; Arslan-Ari, Ismahan

    2011-01-01

    The purpose of this study was to document the design and development of an adaptive system which individualizes instruction such as content, interfaces, instructional strategies, and resources dependent on two factors, namely student motivation and prior knowledge levels. Combining adaptive hypermedia methods with strategies proposed by…

  11. Development of computerized adaptive testing (CAT) for the EORTC QLQ-C30 physical functioning dimension

    DEFF Research Database (Denmark)

    Petersen, Morten Aa; Groenvold, Mogens; Aaronson, Neil K

    2011-01-01

    Computerized adaptive test (CAT) methods, based on item response theory (IRT), enable a patient-reported outcome instrument to be adapted to the individual patient while maintaining direct comparability of scores. The EORTC Quality of Life Group is developing a CAT version of the widely used EORT...

  12. Evaluating Knowledge Structure-Based Adaptive Testing Algorithms and System Development

    Science.gov (United States)

    Wu, Huey-Min; Kuo, Bor-Chen; Yang, Jinn-Min

    2012-01-01

    In recent years, many computerized test systems have been developed for diagnosing students' learning profiles. Nevertheless, it remains a challenging issue to find an adaptive testing algorithm to both shorten testing time and precisely diagnose the knowledge status of students. In order to find a suitable algorithm, four adaptive testing…

  13. Evaluating Knowledge Structure-Based Adaptive Testing Algorithms and System Development

    Science.gov (United States)

    Wu, Huey-Min; Kuo, Bor-Chen; Yang, Jinn-Min

    2012-01-01

    In recent years, many computerized test systems have been developed for diagnosing students' learning profiles. Nevertheless, it remains a challenging issue to find an adaptive testing algorithm to both shorten testing time and precisely diagnose the knowledge status of students. In order to find a suitable algorithm, four adaptive testing…

  14. Development of a SMART core protection system code

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Keung Koo; Lee, Ki Book; In, Wang Ki; Zee, Sung Quun

    2002-01-01

    SMART is a 330MWt integral type pressurized water reactor that can be used for cogeneration, district heating and seawater desalination as well as electricity generation. Online digital SMART core protection system(SCOPS) is one of the advanced technologies which were adopted to improve the SMART safety. SCOPS calculate the minimum DNBR and maximum linear power density based on the several online measured system parameters, such as excore detector signal, CEA positions, MCP pump speed, coolant pressure and temperatures. SCOPS assures that the SAFDL(Specified Acceptance Fuel Design Limit) on DNBR and LPD is not exceeded during the anticipated operational occurrences. This technical report provides a description of the SCOPS protection algorithm to be implemented as the computer program. In addition to this, the requirements on the protection program interfaces, system interfaces, protection program timing, and system initialization are included.

  15. AWARE: Adaptive Software Monitoring and Dynamic Reconfiguration for Critical Infrastructure Protection

    Science.gov (United States)

    2015-04-29

    refactoring object-oriented (OO) designs to improve OO metrics and introduce new design patterns. This technique, called REMODEL , was applied to...driven development artifacts. REMODEL uses a genetic algorithm (GA) to apply different combinations of mini- transformations to existing designs. These...extension of the Plato system that generates architectural models of target system configurations and enables developers to indirectly control the degree

  16. Longitudinal adaptation in language development: a study of typically-developing children and children with ASD

    DEFF Research Database (Denmark)

    Weed, Ethan; Fusaroli, Riccardo; Fein, Deborah

    Background: Children with Autism Spectrum Disorder (ASD) often display distinctive language development trajectories (Tek et al., 2013). Because language-learning is a social endeavor, these trajectories could be partially grounded in the dynamics that characterize the children's social......’s previous behavior. In this study, we tested this model of mutual influence in a longitudinal corpus (6 visits over 2 years), consisting of 30 minutes of controlled playful activities between parents and 66 children (33 ASD and 33 matched typically developing (TD), Goodwin et al. 2012). Methods: We first......’s/child’s behavior at visit N+1 (baselined for her/his behavior at visit N). We used mixed-effects growth curve models to identify the children’s developmental trajectories, and to investigate longitudinal adaptation. The models included random intercepts and slopes to account for individual and group variability.Results:Developmental...

  17. CD47 Promotes Protective Innate and Adaptive Immunity in a Mouse Model of Disseminated Candidiasis.

    Science.gov (United States)

    Navarathna, Dhammika H M L P; Stein, Erica V; Lessey-Morillon, Elizabeth C; Nayak, Debasis; Martin-Manso, Gema; Roberts, David D

    2015-01-01

    CD47 is a widely expressed receptor that regulates immunity by engaging its counter-receptor SIRPα on phagocytes and its secreted ligand thrombospondin-1. Mice lacking CD47 can exhibit enhanced or impaired host responses to bacterial pathogens, but its role in fungal immunity has not been examined. cd47-/- mice on a C57BL/6 background showed significantly increased morbidity and mortality following Candida albicans infection when compared with wild-type mice. Despite normal fungal colonization at earlier times, cd47-/- mice at four days post-infection had increased colonization of brain and kidneys accompanied by stronger inflammatory reactions. Neutrophil and macrophage numbers were significantly elevated in kidneys and neutrophils in the brains of infected cd47-/- mice. However, no defect in phagocytic activity towards C. albicans was observed in cd47-/- bone-marrow-derived macrophages, and neutrophil and macrophage killing of C. albicans was not impaired. CD47-deficiency did not alter the early humoral immune response to C. albicans. Th1, Th2, and Th17 population of CD4+ T cells were expanded in the spleen, and gene expression profiles of spleen and kidney showed stronger pro-inflammatory signaling in infected cd47-/- mice. The chemoattractant chemokines MIP-2α and MIP-2β were highly expressed in infected spleens of cd47-/- mice. G-CSF, GM-CSF, and the inflammasome component NLRP3 were more highly expressed in infected cd47-/- kidneys than in infected wild-type controls. Circulating pro- (TNF-α, IL-6) and anti-inflammatory cytokines (IL-10) were significantly elevated, but IL-17 was decreased. These data indicate that CD47 plays protective roles against disseminated candidiasis and alters pro-inflammatory and immunosuppressive pathways known to regulate innate and T cell immunity.

  18. DEVELOPMENT OF PERSONAL PROTECTIVE EQUIPMENT FOR DECONTAMINATION AND DECOMMISSIONING

    Energy Technology Data Exchange (ETDEWEB)

    M.A. Ebadian, Ph.D.

    1999-01-01

    The purpose of this one-year investigation is to perform a technology integration/search, thereby ensuring that the safest and most cost-effective options are developed and subsequently used during the deactivation and decommissioning (D&D) of U.S. Department of Energy Environmental Management (DOE-EM) sites. Issues of worker health and safety are the main concern, followed by cost. Two lines of action were explored: innovative Personal Cooling Systems (PCS) and Personal Monitoring Equipment (PME). PME refers to sensors affixed to the worker that warn of an approaching heat stress condition, thereby preventing it. Three types of cooling systems were investigated: Pre-Chilled or Forced-Air System (PCFA), Umbilical Fluid-Chilled System (UFCS), and Passive Vest System (PVS). Of these, the UFCS leads the way. The PVS or Gel pack vest lagged due to a limited cooling duration. And the PCFA or chilled liquid air supply was cumbersome and required an expensive and complex recharge system. The UFCS in the form of the Personal Ice Cooling System (PICS) performed exceptionally. The technology uses a chilled liquid circulating undergarment and a Personal Protective Equipment (PPE) external pump and ice reservoir. The system is moderately expensive, but the recharge is low-tech and inexpensive enough to offset the cost. There are commercially available PME that can be augmented to meet the DOE's heat stress alleviation need. The technology is costly, in excess of $4,000 per unit. Workers easily ignore the alarm. The benefit to health & safety is indirect so can be overlooked. A PCS is a more justifiable expenditure.

  19. Development of multifunctional digital bus bar protection relay

    Energy Technology Data Exchange (ETDEWEB)

    Yuki, Masaru; Yoshikawa, Motoyasu; Hayashi, Eiji; Oki, Michio; Matsumoto, Yutaka; Iwaya, fumio; Yoshizumi, Tatunori (Kansai Electric Power Co. Inc., Osaka (Japan); Hitachi Ltd., Tokyo (Japan))

    1989-03-25

    The existing analog bus bar protection relays of a substation have been easily affected by saturation of the current transformer and apt to malfunction at an accident occurred outside. Kansai Electric Power Co. developed jointly with Hitachi Manufacturing Co. a new calculation algorithm to avert the effect of the current transformer saturation (ratio differential relay system with memory of the amount of inhibition) by digitizing the above existing relay. Taking notice of the fact that transient saturation of the current transformer occurs from at least one half wave or later after the accident current started passing, this system memorizes the amount of inhibition of the relay by a signal within the time zone of nonsaturation immediately after the start of the accident current and by this value prevents malfunction at the time of current transformer saturation. The systems to which this relay is applied are as follows: system voltages are 77kV and 154kV for the resistance grounded neutral system, and 275kV for the resistance grounded neutral system and 275kV for the system with solidly earthed neutral. The substations to which this relay is to be installed are medium and large scale substations each of which has 8 or more terminals. Its short circuit capacity is 3,300kVA for the 77kV system, 10,600kVA for the 154kV system and 23,800kVA for the 275kV system. 8 figs., 7 tabs.

  20. An Adaptive Watermarking Technique for the copyright of digital images and Digital Image Protection

    Directory of Open Access Journals (Sweden)

    Yusuf Perwej

    2012-05-01

    Full Text Available The Internet as a whole does not use secure links, thus information in transit may be vulnerable to interruption as well. The important of reducing a chance of the information being detected during the transmission is being an issue in the real world now days. The Digital watermarking method provides for the quick and inexpensive distribution of digital information over the Internet. This method provides new ways of ensuring the sufficient protection of copyright holders in the intellectual property dispersion process. The property of digital watermarking images allows insertion of additional data in the image without altering the value of the image. This message is hidden in unused visual space in the image and stays below the human visible threshold for the image. Both seek to embed information inside a cover message with little or no degradation of the cover-object. In this paper investigate the following relevant concepts and terminology, history of watermarks and the properties of a watermarking system as well as a type of watermarking and applications. We are proposing edge detection using Gabor Filters. In this paper we are proposed least significant bit (LSB substitution method to encrypt the message in the watermark image file. The benefits of the LSB are its simplicity to embed the bits of the message directly into the LSB plane of cover-image and many techniques using these methods. The LSB does not result in a human perceptible difference because the amplitude of the change is little therefore the human eye the resulting stego image will look identical to the cover image and this allows high perceptual transparency of the LSB. The spatial domain technique LSB substitution it would be able to use a pseudo-random number generatorto determine the pixels to be used for embedding based on a given key. We are using DCT transform watermark algorithms based on robustness. The watermarking robustness have been calculated by the Peak Signal to

  1. An Adaptive Watermarking Technique for the copyright of digital images and Digital Image Protection

    Directory of Open Access Journals (Sweden)

    Yusuf Perwej

    2012-04-01

    Full Text Available The Internet as a whole does not use secure links, thus information in transit may be vulnerable to interruption as well. The important of reducing a chance of the information being detected during the transmission is being an issue in the real world now days. The Digital watermarking method provides for the quick and inexpensive distribution of digital information over the Internet. This method provides new ways of ensuring the sufficient protection of copyright holders in the intellectual property dispersion process. The property of digital watermarking images allows insertion of additional data in the image without altering the value of the image. This message is hidden in unused visual space in the image and stays below the human visible threshold for the image. Both seek to embed information inside a cover message with little or no degradation of the cover-object. In this paper investigate the following relevant concepts and terminology, history of watermarks and the properties of a watermarking system as well as a type of watermarking and applications. We are proposing edge detection using Gabor Filters. In this paper we are proposed least significant bit (LSB substitution method to encrypt the message in the watermark image file. The benefits of the LSB are its simplicity to embed the bits of the message directly into the LSB plane of cover-image and many techniques using these methods. The LSB does not result in a human perceptible difference because the amplitude of the change is little therefore the human eye the resulting stego image will look identical to the cover image and this allows high perceptual transparency of the LSB. The spatial domain technique LSB substitution it would be able to use a pseudo-random number generator to determine the pixels to be used for embedding based on a given key. We are using DCT transform watermark algorithms based on robustness. The watermarking robustness have been calculated by the Peak Signal

  2. Standardization of Information Systems Development Processes and Banking Industry Adaptations

    OpenAIRE

    Tuna Ozcer; Zuhal Tanrikulu

    2011-01-01

    This paper examines the current system development processes of three major Turkish banks in terms of compliance to internationally accepted system development and software engineering standards to determine the common process problems of banks. After an in-depth investigation into system development and software engineering standards, related process-based standards were selected. Questions were then prepared covering the whole system development process by applying the classical Waterfall l...

  3. Effects of heat stress on development, reproduction and activities of protective enzymes in Mononychellus mcgregori.

    Science.gov (United States)

    Lu, Fuping; Chen, Qing; Chen, Zhishui; Lu, Hui; Xu, Xuelian; Jing, Fulin

    2014-06-01

    Mononychellus mcgregori is a pest mite of cassava. Since its invasion into China in 2008 it has spread rapidly. In order to determine the potential distribution and to analyze its invasion, diffusion and ecological adaptation mechanisms, we investigated the effect of high-temperature stress (30, 33, 36, 39 and 42 °C) on its development and reproduction, and the activity of protective enzymes in the mite. The results indicated significant influences: (1) adults could not lay eggs after they had been exposed to 42 °C for 4 h or longer; (2) egg development was slower and egg hatchability decreased after exposure of adults to 33-42 °C for 1 h; (3) offspring development (all stages) was slower after exposure of adults to 33-42 °C for 2 h or more; and (4) polyphenol oxidase (PPO), peroxidase (POD), ascorbate peroxidase (APX) and catalase (CAT) activities in the adults increased to high levels after exposure to 33-42 °C for 1 h, and superoxide dismutase activity increased only after exposure to 42 °C for 1 h. In conclusion, exposure to high temperatures for only 1 h probably has an important impact on the mite's population growth. The significant increase of PPO, POD, APX, and CAT activities in adults may partially explain how M. mcgregori survive exposure to a relatively high temperature.

  4. Developing effective rockfall protection barriers for low energy impacts

    Science.gov (United States)

    Mentani, Alessio; Giacomini, Anna; Buzzi, Olivier; Govoni, Laura; Gottardi, Guido; Fityus, Stephen

    2016-04-01

    Recently, important progresses have been made towards the development of high capacity rockfall barriers (100 kJ - 8000 kJ). The interest of researchers and practitioners is now turning to the development of fences of minor capacity, whose use becomes essential in areas where rockfall events generally have low intensity and the use of high capacity barriers would be accompanied by excessive costs and high environmental impact. Low energy barriers can also provide a cost-effective solution even in areas where high energies events are expected. Results of full-scale tests are vital to any investigation on the behaviour of these structures. An experimental set-up has been developed at The University of Newcastle (AUS), to investigate the response of low energy rockfall barrier prototypes to low energy impacts. The Australian territory, and in particular New South Wales, is in fact characterised by rockfall events of low-to-medium intensity (50 kJ - 500 kJ) and the need of protection structures working within such energy range, is particularly felt [1]. The experiments involved the impact of a test block onto three spans, low energy barrier prototypes, made of steel structural posts, fully fixed at the base, side cables and a steel meshwork constituted by a double twist hexagonal wire net [2]. Test data enabled the development, calibration and assessment of FE models [3], on which non-linear and dynamic analyses have been performed addressing the effect of the block size. Results have shown that the response of the structure is strongly governed by the net. Data from tests conducted on the sole net and on the entire barrier showed in fact a similar trend, different to what typically observed for high capacity barriers, whose behaviour is also led by the presence of uphill cables and brakes. In particular, the numerical analyses have demonstrated a dependence of the net performance on the block size. In particular, a loss of capacity in the order of 50% occurred as the

  5. How climate compatible are livelihood adaptation strategies and development programs in rural Indonesia?

    Directory of Open Access Journals (Sweden)

    R.M. Wise

    2016-01-01

    Full Text Available Achieving climate compatible development (CCD is a necessity in developing countries, but there are few examples of requisite planning processes, or manifestations of CCD. This paper presents a multi-stakeholder, participatory planning process designed to screen and prioritise rural livelihood adaptation strategies against nine CCD criteria. The process also integrated three principles of adaptation pathways: interventions should be (1 ‘no regrets’ and maintain reversibility to avoid mal-adaptation; (2 address both proximate and underlying systemic drivers of community vulnerability; and (3 linked across spatial scales and jurisdictional levels to promote coordination. Using examples of two rural sub-districts in Indonesia, we demonstrate the process and resulting CCD strategies. Priority strategies varied between the sub-districts but all reflected standard development interventions: water management, intensification or diversification of agriculture and aquaculture, education, health, food security and skills-building for communities. Strategies delivered co-benefits for human development and ecosystem services and hence adaptive capacity, but greenhouse mitigation co-benefits were less significant. Actions to deliver the strategies’ objectives were screened for reversibility, and a minority were potentially mal-adaptive (i.e. path dependent, disproportionately burdening the most vulnerable, reducing incentives to adapt, or increasing greenhouse gas emissions yet highly feasible. These related to infrastructure, which paradoxically is necessary to deliver ‘soft’ adaptation benefits (i.e. road access to health services. Only a small minority of transformative strategies addressed the systemic (i.e. institutional and political drivers of vulnerability. Strategies were well-matched by development programs, suggesting that current interventions mirror CCD. However, development programs tackled fewer systemic drivers, were poorly

  6. Career adaptability development in adolescence: Multiple predictors and effect on sense of power and life satisfaction

    OpenAIRE

    Hirschi, Andreas

    2009-01-01

    This longitudinal panel study investigated predictors of career adaptability development and its effect on development of sense of power and experience of life satisfaction among 330 Swiss eighth graders. A multivariate measure of career adaptability consisting of career choice readiness, planning, exploration, and confidence was applied. Based on Motivational Systems Theory four groups of predictors were assessed: positive emotional disposition, goal decidedness, capability beliefs and socia...

  7. Standardization of information systems development processes and banking industry adaptations

    CERN Document Server

    Tanrikulu, Zuhal

    2011-01-01

    This paper examines the current system development processes of three major Turkish banks in terms of compliance to internationally accepted system development and software engineering standards to determine the common process problems of banks. After an in-depth investigation into system development and software engineering standards, related process-based standards were selected. Questions were then prepared covering the whole system development process by applying the classical Waterfall life cycle model. Each question is made up of guidance and suggestions from the international system development standards. To collect data, people from the information technology departments of three major banks in Turkey were interviewed. Results have been aggregated by examining the current process status of the three banks together. Problematic issues were identified using the international system development standards.

  8. On-line training in radiological protection by means of the designing and adaptation of a technological platform

    Energy Technology Data Exchange (ETDEWEB)

    Soto, M.; Campayo, J. M. [Logistica y Acondicionamientos Industriales SAU, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain); Mayo, P. [TITANIA Servicios Tecnologicos SL, Sorolla Center, local 10, Av. de las Cortes Valencianas No. 58, 46015 Valencia (Spain); Verdu, G., E-mail: m.soto@lainsa.co [ISIRYM, Universidad Politecnica de Valencia, Camino de Vera s/n, Valencia (Spain)

    2010-10-15

    The companies that are working in maintenance, decontamination, dismantling and assessment in nuclear power plants, usually have their employees in different facilities far from its central offices. When there is a training in radiological protection applied to the nuclear field, it is difficult for these people the attendance to the course because of different reasons. One of them is the location of the formation centres which sometimes are not near from the nuclear facilities, so it is necessary the displacement of the employees, and the time in displacements to the formation centre and costs increase exponentially. In addition if they go to the courses they usually cannot attend their daily work with the same effectiveness depending on the duration of the course. In this work we present a technological platform that is designed in collaboration with the university of give different courses related with radiological field applied to nuclear and radioactive facilities. This platform is adapted and designed to different contents depending on the course. At the main screen we have included and index and announces of the course, so we have arranged the contents in different areas and sections. When the student finishes an area, an evaluation has to be done to prove the understanding of the lessons. We have included films of different activities as decontamination devices, radiation detectors, etc. with the contents to make the explanations more understandable to the student. The student can access to this platform with private password and follow the course individually. The course is complemented with a final review and exam that are not online to guarantee that the training is well finished. This type of training is more flexitime and can be adapted to the necessities of each user, avoiding high costs and unnecessary displacements. (Author)

  9. Developments in Intellectual Property and Traditional Knowledge Protection

    Science.gov (United States)

    Anderson, Jane

    2009-01-01

    In order to protect indigenous/traditional knowledge, intellectual property law must be leveraged in a way that is responsive to the dynamic inter-relationships between law, society and culture. Over the last decade, increased attention to Indigenous concerns has produced a wealth of literature and prompted recognition of the diverse needs of…

  10. Development of nanostructured protective "sight glasses" for IR gas sensors

    DEFF Research Database (Denmark)

    Bergmann, René; Davis, Zachary James; Schmidt, Michael Stenbæk

    2011-01-01

    In this work protective "sight glasses" for infrared gas sensors showing a sub-wavelength nanostructure with random patterns have been fabricated by reactive ion etching (RIE) in an easy and comparable cheap single step mask-less process. By an organic coating, the intrinsic water repellent...

  11. Adaptive and cross-protective responses against cadmium and zinc toxicity in cadmium-resistant bacterium isolated from a zinc mine

    Directory of Open Access Journals (Sweden)

    Benjaphorn Prapagdee

    2009-12-01

    Full Text Available Cadmium (Cd is a major environmental hazard, which usually is detected in its ionic form of Cd2+. It also causes adverse toxic effects on human health and other living organisms. Cd-resistant bacteria were isolated from Cd-contaminated soils. One isolate, TAK1, was highly resistance level to Cd toxicity. TAK1 was isolated from soil contaminated with a high Cd concentration (204.1 mg.kg-1. The result of 16S rDNA sequence analysis found that the TAK1 showed the similarity to Ralstonia sp. Physiological adaptive and cross-protective responses to Cd and Zn killing were investigated in Ralstonia sp.TAK1. Exposure to a low concentration of Cd induced adaptive resistance to higher concentrations of Cd. In addition, pretreatment of Ralstonia sp.TAK1 with an inducing concentration of Cd conferred cross-protective response against subsequent exposure to the lethal concentrations of Zn. The induced adaptive and cross-protective response Ralstonia sp.TAK1 required newly synthesized protein(s. Cd-induced adaptive and cross-protective responses against Cd and Zn toxicity are the important mechanisms used by Ralstonia sp.TAK1 to survive in the heavy metal contaminated environments. These findings might lead to the use of Ralstonia sp.TAK1 for microbial based remediation in Cd and Zn-contaminated soils.

  12. Estimating the effect of protected lands on the development and conservation of their surroundings.

    Science.gov (United States)

    McDonald, Robert I; Yuan-Farrell, Chris; Fievet, Charles; Moeller, Matthias; Kareiva, Peter; Foster, David; Gragson, Ted; Kinzig, Ann; Kuby, Lauren; Redman, Charles

    2007-12-01

    The fate of private lands is widely seen as key to the fate of biodiversity in much of the world. Organizations that work to protect biodiversity on private lands often hope that conservation actions on one piece of land will leverage the actions of surrounding landowners. Few researchers have, however, examined whether protected lands do in fact encourage land conservation nearby or how protected lands affect development in the surrounding landscape. Using spatiotemporal data sets on land cover and land protection for three sites (western North Carolina, central Massachusetts, and central Arizona), we examined whether the existence of a protected area correlates with an increased rate of nearby land conservation or a decreased rate of nearby land development. At all sites, newly protected conservation areas tended to cluster close to preexisting protected areas. This may imply that the geography of contemporary conservation actions is influenced by past decisions on land protection, often made for reasons far removed from concerns about biodiversity. On the other hand, we found no evidence that proximity to protected areas correlates with a reduced rate of nearby land development. Indeed, on two of our three sites the development rate was significantly greater in regions with more protected land. This suggests that each conservation action should be justified and valued largely for what is protected on the targeted land, without much hope of broader conservation leverage effects.

  13. Selection of Numerical Criterion Value for Determination of Short Circuit Type in Adaptive Micro-Processing Current Protection of Electric Power Lines

    Directory of Open Access Journals (Sweden)

    A. V. Kovalevsky

    2007-01-01

    Full Text Available The paper considers a principle for determination of a short circuit type which is used in the mathematical model of adaptive micro-processing protection with the purpose to improve sensitivity. As a result of a calculative experiment dependences ΔI(t for various short circuit types (three- and two-phase short circuits have been obtained at a number of points of the investigated power network. These dependences make it possible to determine a numerical value of ΔI coefficient. A comparative analysis has been made to study an operation of adaptive and non-adaptive microprocessing protections in the case of asymmetric damages of the investigated power network just in the same points.

  14. A chromosomally encoded virulence factor protects the Lyme disease pathogen against host-adaptive immunity.

    Directory of Open Access Journals (Sweden)

    Xiuli Yang

    2009-03-01

    Full Text Available Borrelia burgdorferi, the bacterial pathogen of Lyme borreliosis, differentially expresses select genes in vivo, likely contributing to microbial persistence and disease. Expression analysis of spirochete genes encoding potential membrane proteins showed that surface-located membrane protein 1 (lmp1 transcripts were expressed at high levels in the infected murine heart, especially during early stages of infection. Mice and humans with diagnosed Lyme borreliosis also developed antibodies against Lmp1. Deletion of lmp1 severely impaired the pathogen's ability to persist in diverse murine tissues including the heart, and to induce disease, which was restored upon chromosomal complementation of the mutant with the lmp1 gene. Lmp1 performs an immune-related rather than a metabolic function, as its deletion did not affect microbial persistence in immunodeficient mice, but significantly decreased spirochete resistance to the borreliacidal effects of anti-B. burgdorferi sera in a complement-independent manner. These data demonstrate the existence of a virulence factor that helps the pathogen evade host-acquired immune defense and establish persistent infection in mammals.

  15. Development of REvolutionary Adaptive Morphing UAV (DREAM-UAV) Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NextGen Aeronautics, Inc. proposes the development of the innovative use of morphing structures for maneuver and flight control as a project for NASA?s Revolutionary...

  16. Adaptive immunity against Leishmania nucleoside hydrolase maps its c-terminal domain as the target of the CD4+ T cell-driven protective response.

    Directory of Open Access Journals (Sweden)

    Dirlei Nico

    Full Text Available Nucleoside hydrolases (NHs show homology among parasite protozoa, fungi and bacteria. They are vital protagonists in the establishment of early infection and, therefore, are excellent candidates for the pathogen recognition by adaptive immune responses. Immune protection against NHs would prevent disease at the early infection of several pathogens. We have identified the domain of the NH of L. donovani (NH36 responsible for its immunogenicity and protective efficacy against murine visceral leishmaniasis (VL. Using recombinant generated peptides covering the whole NH36 sequence and saponin we demonstrate that protection against L. chagasi is related to its C-terminal domain (amino-acids 199-314 and is mediated mainly by a CD4+ T cell driven response with a lower contribution of CD8+ T cells. Immunization with this peptide exceeds in 36.73±12.33% the protective response induced by the cognate NH36 protein. Increases in IgM, IgG2a, IgG1 and IgG2b antibodies, CD4+ T cell proportions, IFN-γ secretion, ratios of IFN-γ/IL-10 producing CD4+ and CD8+ T cells and percents of antibody binding inhibition by synthetic predicted epitopes were detected in F3 vaccinated mice. The increases in DTH and in ratios of TNFα/IL-10 CD4+ producing cells were however the strong correlates of protection which was confirmed by in vivo depletion with monoclonal antibodies, algorithm predicted CD4 and CD8 epitopes and a pronounced decrease in parasite load (90.5-88.23%; p = 0.011 that was long-lasting. No decrease in parasite load was detected after vaccination with the N-domain of NH36, in spite of the induction of IFN-γ/IL-10 expression by CD4+ T cells after challenge. Both peptides reduced the size of footpad lesions, but only the C-domain reduced the parasite load of mice challenged with L. amazonensis. The identification of the target of the immune response to NH36 represents a basis for the rationale development of a bivalent vaccine against leishmaniasis and

  17. Younger is not always better: development of locomotor adaptation from childhood to adulthood.

    Science.gov (United States)

    Vasudevan, Erin V L; Torres-Oviedo, Gelsy; Morton, Susanne M; Yang, Jaynie F; Bastian, Amy J

    2011-02-23

    New walking patterns can be learned over short timescales (i.e., adapted in minutes) using a split-belt treadmill that controls the speed of each leg independently. This leads to storage of a modified spatial and temporal motor pattern that is expressed as an aftereffect in regular walking conditions. Because split-belt walking is a novel task for adults and children alike, we used it to investigate how motor adaptation matures during human development. We also asked whether the immature pattern resembles that of people with cerebellar dysfunction, because we know that this adaptation depends on cerebellar integrity. Healthy children (3-18 years old) and adults, and individuals with cerebellar damage were adapted while walking on split belts (1:2 speed ratio). Adaptation and de-adaptation rates were quantified separately for temporal and spatial parameters. All healthy children and adults tested could learn the new timing at the same rate and showed significant aftereffects. However, children younger than 6 years old were unable to learn the new spatial coordination. Furthermore, children as old as age 11 years old showed slower rates of adaptation and de-adaptation of spatial parameters of walking. Young children showed patterns similar to cerebellar patients, with greater deficits in spatial versus temporal adaptation. Thus, although walking is a well-practiced, refined motor skill by late childhood (i.e., 11 years of age), the processes underlying learning new spatial relationships between the legs are still developing. The maturation of locomotor adaptation follows at least two time courses, which we propose is determined by the developmental state of the cerebellum.

  18. [Protection of radiosensitive human cells against the action of heavy metals by antimutagens and adapting factors: association with genetic and protein polymorphisms].

    Science.gov (United States)

    Vasil'eva, I M; Shagirova, Zh M; Sinel'shchikova, T A; Mavletova, D A; Kuz'mina, N S; Zasukhina, G D

    2009-06-01

    Cells of a diploid line obtained from embryos with the Down's syndrome, known to be unable to repair gamma-induced DNA damage, were treated with natural (garlic extract, retinol) and synthetic (crown compound) antimutagens and with adapting factors (heat shock, low CdCl2 concentrations, 10(-8) M). The protective effect was evaluated by registering DNA breaks and cell survival, and the protection coefficients were calculated. The most effective results were obtained with the use of the garlic extract and retinol. No protection of the DNA structure was observed when cells were treated with low concentrations of cadmium chloride and then with high concentrations, i. e., no adaptive response (AR) was formed under these conditions. The spectrum of proteins in treated and control cells as well as detoxication genes (GSTM1, GSTT1 , CYPIA1) were determined.

  19. Development and Progress through Intellectual Property Protection and Leverage

    Directory of Open Access Journals (Sweden)

    Gabriel I. NĂSTASE

    2012-02-01

    Full Text Available Worldwide, every year, cultural, scientific and technical dimensions increases its value as a result of spiritual and creative members of society. Since surplus value and prosperity is a consequence of the act of creation, protection of creators and their creations to be one of the main factors that we must take into consideration and those involved in national security system structures.Basically, protection creators respectively Patent, design and trademark licenses, the designs, is made by a legal institution of intellectual property, which is the State Office for Inventions and Trademarks (OSIM - government organ specialty, with unique authority in Romania, acting in accordance with law and the provisions of international conventions to which the Romanian State is party.

  20. Predicting intentions to consume functional foods and supplements to offset memory loss using an adaptation of protection motivation theory.

    Science.gov (United States)

    Cox, D N; Koster, A; Russell, C G

    2004-08-01

    The widespread use of dietary supplements and so-called 'functional foods' is thought to be partially motivated by self-control of health. However, whilst consumers want foods associated with well-being or disease prevention, they are unlikely to be willing to compromise on taste or technology. This presents a dilemma for promoters of functional foods. Middle-aged consumers' intentions to consume functional foods or supplements that may improve memory were tested within an adaptation of Protection Motivation theory (PMT). Participants evaluated text descriptions of four products described as: having an unpleasant bitter taste (Natural-FF); having 'additives' to reduce bitterness (Sweetened-FF); being genetically modified to enhance function (GM-FF) and Supplements. Participants were recruited as being of high and low perceived vulnerability to memory failure. In total, 290 middle-aged consumers (aged 40-60 years) participated in the study. Motivations to consume the GM-FF were the lowest. There were gender differences between intention to consume the supplements, Natural-FF and Sweetened-FF and product differences within genders. Women were less favourable than men in their attitudes towards genetic modification in general. Regression analyses indicated that PM predictors of intention to consume functional foods or supplements explained 59-63% of the variance (R2). Overall, perceived 'efficacy' (of the behaviour) and self-efficacy were the most important predictors of intentions to consume.

  1. STEM CELL RESEARCH DEVELOPMENT AND ITS PROTECTION IN INDONESIA

    Directory of Open Access Journals (Sweden)

    Tomi Suryo Utomo

    2013-02-01

    Full Text Available This research discusses the possibility of patenting stem cells under the Indonesian patent law by focusing on two essential issues: (a what approaches should be chosen by the Indonesian government to protect stem cell research under the Indonesian Patent Act and non-patent regulations? and (b what types of stem cells can be protected under the Indonesian Patent Act? In order to provide comparative perspectives, this paper discusses the experience and policies of the US, German and South Korean governments in protecting stem cell research under their patent acts. Penelitian ini mendiskusikan kemungkinan mematenkan sel punca dalam hukum paten di Indonesia dengan memfokuskan pada dua isu pokok: (a Pendekatan apa yang sebaiknya dipilih oleh pemerintahan Indonesia untuk melindungi penelitian sel punca dalam hukum paten Indonesia dan peraturan non paten? (b Tipe sel punca apa yang dapat dilindungi dalam hukum paten Indonesia? Untuk mencakupi pendekatan melalui perbandingan dengan luar negeri, penelitian ini membahas pengalaman dan kebijakan di pemerintahan AS, Jerman, dan Korea Selatan dalam melindungi penelitan sel punca dalam hukum paten masing-masing negara.

  2. A Adaptive XP-based approach to Agile Development

    CERN Document Server

    Liao, Gang; Luo, Lian

    2012-01-01

    Software design is gradually becoming open, distributed, pervasive, and connected. It is a sad statistical fact that software projects are scientifically fragile and tend to fail more than other engineering fields. Agile development is a philosophy. And agile methods are processes that support the agile philosophy. XP places a strong emphasis on technical practices in addition to the more common teamwork and structural practices. In this paper, we elaborate how XP practices can be used to thinking, collaborating, releasing, planning, developing. And the state that make your team and organization more successful.

  3. Social Protection as Development Policy: A New International Agenda for Action

    Directory of Open Access Journals (Sweden)

    François-Xavier Merrien

    2013-06-01

    Full Text Available At the turn of the millennium, social protection became a new priority for both states of the global South and international development policy more generally. As, in the past, social protection policies were considered unsuitable for development countries, the elevation of social protection to the level of a preferred instrument of development marks a fundamental paradigm shift. This shift began in the late 1990s, driven by disenchantment with the results of economic adjustment programmes, the 1997 Asian economic crisis, and a heightened awareness of the negative effects of global poverty. Social protection thus became a preferred instrument of the Millennium Development Goals, while the World Bank promoted social protection as a key component of international poverty reduction strategies (social risk management. The Department for International Development (DfID in the United Kingdom, along with other organisations, promoted a development model centred on the rights of the poor. Successful social protection programmes developed in the Global South – such as Brazilian and South African social pension schemes and conditional cash transfers (CCT established in Mexico and Brazil – were adopted as model programmes at the global level. The purpose of this article is to analyse the emergence of social protection in development policies. From this perspective, it examines the various types of programmes promoted by the international community, with a specific focus on CCT. It concludes with an assessment of the relative appropriateness of social protection policies for developing countries.

  4. Adaptive Role-Play Exercises for a Leader Development Center

    Science.gov (United States)

    2006-11-01

    effort addresses development of high-level requirements such that shipboard content management system functionality can be implemented using SCORM and...ALS) is composed of a simplistic Learner Management System (LMS), a simplistic Learning Content Management System (LCMS) and a reference Simulation

  5. Technology Needs for Teachers Web Development and Curriculum Adaptations

    Science.gov (United States)

    Carroll, Christy J.

    1999-01-01

    Computer-based mathematics and science curricula focusing on NASA inventions and technologies will enhance current teacher knowledge and skills. Materials and interactive software developed by educators will allow students to integrate their various courses, to work cooperatively, and to collaborate with both NASA scientists and students at other locations by using computer networks, email and the World Wide Web.

  6. Protective

    Directory of Open Access Journals (Sweden)

    Wessam M. Abdel-Wahab

    2013-10-01

    Full Text Available Many active ingredients extracted from herbal and medicinal plants are extensively studied for their beneficial effects. Antioxidant activity and free radical scavenging properties of thymoquinone (TQ have been reported. The present study evaluated the possible protective effects of TQ against the toxicity and oxidative stress of sodium fluoride (NaF in the liver of rats. Rats were divided into four groups, the first group served as the control group and was administered distilled water whereas the NaF group received NaF orally at a dose of 10 mg/kg for 4 weeks, TQ group was administered TQ orally at a dose of 10 mg/kg for 5 weeks, and the NaF-TQ group was first given TQ for 1 week and was secondly administered 10 mg/kg/day NaF in association with 10 mg/kg TQ for 4 weeks. Rats intoxicated with NaF showed a significant increase in lipid peroxidation whereas the level of reduced glutathione (GSH and the activity of superoxide dismutase (SOD, catalase (CAT, glutathione S-transferase (GST and glutathione peroxidase (GPx were reduced in hepatic tissues. The proper functioning of the liver was also disrupted as indicated by alterations in the measured liver function indices and biochemical parameters. TQ supplementation counteracted the NaF-induced hepatotoxicity probably due to its strong antioxidant activity. In conclusion, the results obtained clearly indicated the role of oxidative stress in the induction of NaF toxicity and suggested hepatoprotective effects of TQ against the toxicity of fluoride compounds.

  7. The political ecology of climate change adaptation livelihoods, agrarian change and the conflicts of development

    CERN Document Server

    Taylor, Marcus

    2014-01-01

    This book provides the first systematic critique of the concept of climate change adaptation within the field of international development. Drawing on a reworked political ecology framework, it argues that climate is not something 'out there' that we adapt to. Instead, it is part of the social and biophysical forces through which our lived environments are actively yet unevenly produced. From this original foundation, the book challenges us to rethink the concepts of climate change, vulnerability, resilience and adaptive capacity in transformed ways. With case studies drawn from Pakistan, Indi

  8. Characteristics of fracture development and gas extraction of a lower protected seam

    Institute of Scientific and Technical Information of China (English)

    王海锋

    2009-01-01

    To ensure the mining safety of working face in the protective seam and meanwhile extract pressure-relief gas of the lower protected seam and eliminate its outburst risk,the present study researched into fracture development of floor coal-rock mass of the protective seam and migration rule of pressure-relief gas from a protected seam so as to obtain an effective pressure- relief gas extraction method.The results show that after the upper protective seam was mined,mining-induced fracturing floor coal-rock mas...

  9. Developing DNP students as adaptive leaders: a key strategy in transforming health care.

    Science.gov (United States)

    Kendall-Gallagher, Deborah; Breslin, Eileen

    2013-01-01

    The success of graduates with a doctor of nursing practice (DNP) degree in transforming health care will depend significantly on their leadership ability to think strategically, innovate, and engage stakeholders in meaningful system improvement. Known as adaptive work, these graduates will need a portfolio of adaptive leadership skills that prepare them to move health care from a volume-driven to value-based system. This article describes development of a core DNP leadership course in a postmaster's point of entry DNP program at an academic health science center school of nursing. The course, designed as DNP students' initial step on their professional development journey to becoming adaptive leaders capable of driving transformative change, created an alternative lens for students to undertake strategic adaptive change initiatives within themselves and their organizations.

  10. Understanding and Developing Adaptive Leadership during Pre-Commissioning

    Science.gov (United States)

    2010-05-21

    precision possible in a laboratory. Close combat is messy.”55 The RETO Study, whose underlying theme was a leader’s requirement to “think and decide... RETO ) Study. 56 53 Henry G. Gole, General William E. DePuy: Preparing the Army for...Modern War (Lexington, KY: The University Press of Kentucky, 2008), 251. Unlike previous studies of officer development, the 1978 RETO Study did not

  11. Runtime Assurance Framework Development for Highly Adaptive Flight Control Systems

    Science.gov (United States)

    2015-12-01

    amongst all members of the fleet. Each vehicle offers its own solution based on its current sensor input, current knowledge , and current situational...switching condition objectives, we have yet to solve the curse of dimensionality associated with the highly complex, multi-dimensional nature of the...these approaches be further pursued. Related to the curse of dimensionality problem is the development of methods for streamlining construction of

  12. The beauty of simple adaptive control and new developments in nonlinear systems stability analysis

    Science.gov (United States)

    Barkana, Itzhak

    2014-12-01

    Although various adaptive control techniques have been around for a long time and in spite of successful proofs of stability and even successful demonstrations of performance, the eventual use of adaptive control methodologies in practical real world systems has met a rather strong resistance from practitioners and has remained limited. Apparently, it is difficult to guarantee or even understand the conditions that can guarantee stable operations of adaptive control systems under realistic operational environments. Besides, it is difficult to measure the robustness of adaptive control system stability and allow it to be compared with the common and widely used measure of phase margin and gain margin that is utilized by present, mainly LTI, controllers. Furthermore, customary stability analysis methods seem to imply that the mere stability of adaptive systems may be adversely affected by any tiny deviation from the pretty idealistic and assumably required stability conditions. This paper first revisits the fundamental qualities of customary direct adaptive control methodologies, in particular the classical Model Reference Adaptive Control, and shows that some of their basic drawbacks have been addressed and eliminated within the so-called Simple Adaptive Control methodology. Moreover, recent developments in the stability analysis methods of nonlinear systems show that prior conditions that were customarily assumed to be needed for stability are only apparent and can be eliminated. As a result, sufficient conditions that guarantee stability are clearly stated and lead to similarly clear proofs of stability. As many real-world applications show, once robust stability of the adaptive systems can be guaranteed, the added value of using Add-On Adaptive Control along with classical Control design techniques is pushing the desired performance beyond any previous limits.

  13. The beauty of simple adaptive control and new developments in nonlinear systems stability analysis

    Energy Technology Data Exchange (ETDEWEB)

    Barkana, Itzhak, E-mail: ibarkana@gmail.com [BARKANA Consulting, Ramat Hasharon (Israel)

    2014-12-10

    Although various adaptive control techniques have been around for a long time and in spite of successful proofs of stability and even successful demonstrations of performance, the eventual use of adaptive control methodologies in practical real world systems has met a rather strong resistance from practitioners and has remained limited. Apparently, it is difficult to guarantee or even understand the conditions that can guarantee stable operations of adaptive control systems under realistic operational environments. Besides, it is difficult to measure the robustness of adaptive control system stability and allow it to be compared with the common and widely used measure of phase margin and gain margin that is utilized by present, mainly LTI, controllers. Furthermore, customary stability analysis methods seem to imply that the mere stability of adaptive systems may be adversely affected by any tiny deviation from the pretty idealistic and assumably required stability conditions. This paper first revisits the fundamental qualities of customary direct adaptive control methodologies, in particular the classical Model Reference Adaptive Control, and shows that some of their basic drawbacks have been addressed and eliminated within the so-called Simple Adaptive Control methodology. Moreover, recent developments in the stability analysis methods of nonlinear systems show that prior conditions that were customarily assumed to be needed for stability are only apparent and can be eliminated. As a result, sufficient conditions that guarantee stability are clearly stated and lead to similarly clear proofs of stability. As many real-world applications show, once robust stability of the adaptive systems can be guaranteed, the added value of using Add-On Adaptive Control along with classical Control design techniques is pushing the desired performance beyond any previous limits.

  14. Development of comorbidity-adapted exercise protocols for patients with knee osteoarthritis

    Science.gov (United States)

    de Rooij, Mariëtte; van der Leeden, Marike; Avezaat, Ellis; Häkkinen, Arja; Klaver, Rob; Maas, Tjieu; Peter, Wilfred F; Roorda, Leo D; Lems, Willem F; Dekker, Joost

    2014-01-01

    Background Exercise therapy is generally recommended for patients with osteoarthritis (OA) of the knee. Comorbidity, which is highly prevalent in OA, may interfere with exercise therapy. To date, there is no evidence-based protocol for the treatment of patients with knee OA and comorbidity. Special protocols adapted to the comorbidity may facilitate the application of exercise therapy in patients with knee OA and one or more comorbidities. Purpose The purpose of this study was to develop comorbidity-adapted exercise protocols for patients with knee OA and comorbidity. Method Several steps were undertaken to develop comorbidity-adapted protocols: selection of highly prevalent comorbidities in OA, a literature search to identify restrictions and contraindications for exercise therapy for the various comorbid diseases, consultation of experts on each comorbid disease, and field testing of the protocol in eleven patients with knee OA and comorbidity. Results Based on literature and expert opinion, comorbidity-adapted protocols were developed for highly prevalent comorbidities in OA. Field testing showed that the protocols provided guidance in clinical decision making in both the diagnostic and the treatment phase. Because of overlap, the number of exercise protocols could be reduced to three: one for physiological adaptations (coronary disease, heart failure, hypertension, diabetes type 2, chronic obstructive pulmonary diseases, obesity), one for behavioral adaptations (chronic a-specific pain, nonspecific low back pain, depression), and one for environmental adaptations (visual or hearing impairments). Evaluation of patient outcome after treatment showed significant (P<0.05) and clinically relevant improvements in activity limitations and pain. Conclusion Comorbidity-adapted exercise protocols for patients with knee OA were developed, providing guidance in clinical reasoning with regard to diagnostics and treatment. To evaluate the effectiveness of treatment in line

  15. Sleep Lab Adaptation in Children with Attention-Deficit/Hyperactivity Disorder and Typically Developing Children

    OpenAIRE

    Meredith Bessey; Jennifer Richards; Penny Corkum

    2013-01-01

    Objectives. Research has shown inconsistencies across studies examining sleep problems in children with attention-deficit/hyperactivity disorder (ADHD). It is possible that these inconsistencies are due to sleep lab adaptation. The goal of the current study was to investigate the possibility that children with ADHD adapt differently to the sleep lab than do typically developing (TD) children. Patients and Methods. Actigraphy variables were compared between home and the sleep lab. Sleep lab ad...

  16. Development of nanostructured protective "sight glasses" for IR gas sensors

    Science.gov (United States)

    Bergmann, René; Davis, Zachary James; Schmidt, Michael Stenbæk; Clausen, Sønnik; Boisen, Anja; Jensen, Jens Møller; Buchner, Rainer; Stolberg-Rohr, Thomine; Jakobsen, Mogens Havsteen

    2011-06-01

    In this work protective "sight glasses" for infrared gas sensors showing a sub-wavelength nanostructure with random patterns have been fabricated by reactive ion etching (RIE) in an easy and comparable cheap single step mask-less process. By an organic coating, the intrinsic water repellent property of the surface could be enhanced, shown by contact angle and roll-off angle measurements. The "self-cleaning" surface property and chemical robustness towards aggressive environments are demonstrated. FT-IR spectroscopy concerning the optical properties of these nanostructured silicon windows revealed a stable anti-reflective "moth-eye" effect in certain wavelength ranges owing to the nanostructures.

  17. Adaptation of pancreatic islet cyto-architecture during development

    Science.gov (United States)

    Striegel, Deborah A.; Hara, Manami; Periwal, Vipul

    2016-04-01

    Plasma glucose in mammals is regulated by hormones secreted by the islets of Langerhans embedded in the exocrine pancreas. Islets consist of endocrine cells, primarily α, β, and δ cells, which secrete glucagon, insulin, and somatostatin, respectively. β cells form irregular locally connected clusters within islets that act in concert to secrete insulin upon glucose stimulation. Varying demands and available nutrients during development produce changes in the local connectivity of β cells in an islet. We showed in earlier work that graph theory provides a framework for the quantification of the seemingly stochastic cyto-architecture of β cells in an islet. To quantify the dynamics of endocrine connectivity during development requires a framework for characterizing changes in the probability distribution on the space of possible graphs, essentially a Fokker-Planck formalism on graphs. With large-scale imaging data for hundreds of thousands of islets containing millions of cells from human specimens, we show that this dynamics can be determined quantitatively. Requiring that rearrangement and cell addition processes match the observed dynamic developmental changes in quantitative topological graph characteristics strongly constrained possible processes. Our results suggest that there is a transient shift in preferred connectivity for β cells between 1-35 weeks and 12-24 months.

  18. Research to Integrate Productivity Enhancement, Environmental Protection, and Human Development

    Directory of Open Access Journals (Sweden)

    Bruce Campbell

    2002-01-01

    Full Text Available To meet the challenges of poverty and environmental sustainability, a different kind of research will be needed. This research will need to embrace the complexity of these systems by redirecting the objectives of research toward enhancing adaptive capacity, by incorporating more participatory approaches, by embracing key principles such as multi-scale analysis and intervention, and by the use of a variety of tools (e.g., systems analysis, information management tools, and impact assessment tools. Integration will be the key concept in the new approach; integration across scales, components, stakeholders, and disciplines. Integrated approaches, as described in this Special Feature, will require changes in the culture and organization of research.

  19. The Adaptability of Marketing Systems to Interventions in Developing Countries: Evidence from the Pineapple System in Benin

    NARCIS (Netherlands)

    Hounhouigan, M.H.; Ingenbleek, P.T.M.; Lans, van der I.A.; Trijp, van H.C.M.; Linnemann, A.R.

    2014-01-01

    In general marketing theory, marketing systems are assumed to adapt to facilitate further economic development. However, such adaptability may be less obvious in the context of developing countries due to features in the social matrix of these countries. The present study explores adaptation in the

  20. Family influences on adaptive development in young children with Down syndrome.

    Science.gov (United States)

    Hauser-Cram, P; Warfield, M E; Shonkoff, J P; Krauss, M W; Upshur, C C; Sayer, A

    1999-01-01

    In this study we investigated the extent to which the family environment predicted differences in trajectories of adaptive development in young children with Down syndrome. The sample was comprised of 54 children with Down syndrome and their families who were studied from infancy through the age of 5 years as part of a longitudinal study of children with disabilities. Hierarchical linear modeling (HLM) was used to estimate the parameters of hierarchical growth models in domains of adaptive development. Results indicated that growth in communication, daily living skills, and socialization domains were predicted by measures of the family environment (i.e., family cohesion and mother-child interaction) above and beyond that predicted by maternal education. Further, Bayley MDI measures during infancy did not predict changes in adaptive development in any of the domains. The results are discussed in terms of implications for service provision and for expanding theoretical frameworks to include the development of children with disabilities.

  1. Development of Vegetation-Pervious Concrete in Grid Beam System for Soil Slope Protection.

    Science.gov (United States)

    Bao, Xiaohua; Liao, Wenyu; Dong, Zhijun; Wang, Shanyong; Tang, Waiching

    2017-01-24

    One of the most efficient and environmentally friendly methods for preventing a landslide on a slope is to vegetate it. Vegetation-pervious concretes have a promising potential for soil protection. In this study, the vegetation-pervious concrete with low alkalinity was developed and studied. Combined with a grid beam structure system, the stability and strength between the vegetation-pervious concrete and base soil are believed to be enhanced effectively. For improving plant adaptability, the alkalinity of concrete can be decreased innovatively by adding a self-designed admixture into the cement paste. The effects of the admixture content on alkalinity and compressive strength of the hardened pervious concrete were investigated using X-ray diffraction (XRD) and compression test, respectively. Meanwhile, the permeability of the vegetation-pervious concrete was studied as well. Through comparing with ordinary pervious concrete, the effect of low alkaline pervious concrete on vegetation growth was investigated in a small-scale field for ten weeks. The test results indicated that the alkalinity of the cement samples decreased with the increase of admixture content, and the vegetation grew successfully on previous concrete. By increasing the admixture content to approximately 3.6%, the compressive strength of pervious concrete was more than 25 MPa.

  2. Development of Vegetation-Pervious Concrete in Grid Beam System for Soil Slope Protection

    Directory of Open Access Journals (Sweden)

    Xiaohua Bao

    2017-01-01

    Full Text Available One of the most efficient and environmentally friendly methods for preventing a landslide on a slope is to vegetate it. Vegetation-pervious concretes have a promising potential for soil protection. In this study, the vegetation-pervious concrete with low alkalinity was developed and studied. Combined with a grid beam structure system, the stability and strength between the vegetation-pervious concrete and base soil are believed to be enhanced effectively. For improving plant adaptability, the alkalinity of concrete can be decreased innovatively by adding a self-designed admixture into the cement paste. The effects of the admixture content on alkalinity and compressive strength of the hardened pervious concrete were investigated using X-ray diffraction (XRD and compression test, respectively. Meanwhile, the permeability of the vegetation-pervious concrete was studied as well. Through comparing with ordinary pervious concrete, the effect of low alkaline pervious concrete on vegetation growth was investigated in a small-scale field for ten weeks. The test results indicated that the alkalinity of the cement samples decreased with the increase of admixture content, and the vegetation grew successfully on previous concrete. By increasing the admixture content to approximately 3.6%, the compressive strength of pervious concrete was more than 25 MPa.

  3. Recommendations for adaptation and validation of commercial kits for biomarker quantification in drug development.

    Science.gov (United States)

    Khan, Masood U; Bowsher, Ronald R; Cameron, Mark; Devanarayan, Viswanath; Keller, Steve; King, Lindsay; Lee, Jean; Morimoto, Alyssa; Rhyne, Paul; Stephen, Laurie; Wu, Yuling; Wyant, Timothy; Lachno, D Richard

    2015-01-01

    Increasingly, commercial immunoassay kits are used to support drug discovery and development. Longitudinally consistent kit performance is crucial, but the degree to which kits and reagents are characterized by manufacturers is not standardized, nor are the approaches by users to adapt them and evaluate their performance through validation prior to use. These factors can negatively impact data quality. This paper offers a systematic approach to assessment, method adaptation and validation of commercial immunoassay kits for quantification of biomarkers in drug development, expanding upon previous publications and guidance. These recommendations aim to standardize and harmonize user practices, contributing to reliable biomarker data from commercial immunoassays, thus, enabling properly informed decisions during drug development.

  4. Performance Analysis Of A Upnp/Dhcompliant Robotic Adapter For Collaborative Tasks Development

    Directory of Open Access Journals (Sweden)

    Alejandro Alvarez Vazquez

    2012-02-01

    Full Text Available This paper describes the performance analysis of an adapter in accordance with standard UPnP DHCompliant (Digital Home Compliant for a service robot. The DHCompliant adapter has been developed to solve some limitations that UPnP protocol suffers and to develop new DHC concepts. Moreover, it showcases with a particular example how the open protocol DHC is useful for the development of collaborative tasks, localization, energy management and other fields altogether. That interoperability is being done between devices obtaining a virtual device which can obtain the controlpoint logic and the device logic simultaneously.

  5. Global assessment of technological innovation for climate change adaptation and mitigation in developing world.

    Science.gov (United States)

    Adenle, Ademola A; Azadi, Hossein; Arbiol, Joseph

    2015-09-15

    Concerns about mitigating and adapting to climate change resulted in renewing the incentive for agricultural research investments and developing further innovation priorities around the world particularly in developing countries. In the near future, development of new agricultural measures and proper diffusion of technologies will greatly influence the ability of farmers in adaptation and mitigation to climate change. Using bibliometric approaches through output of academic journal publications and patent-based data, we assess the impact of research and development (R&D) for new and existing technologies within the context of climate change mitigation and adaptation. We show that many developing countries invest limited resources for R&D in relevant technologies that have great potential for mitigation and adaption in agricultural production. We also discuss constraints including weak infrastructure, limited research capacity, lack of credit facilities and technology transfer that may hinder the application of innovation in tackling the challenges of climate change. A range of policy measures is also suggested to overcome identified constraints and to ensure that potentials of innovation for climate change mitigation and adaptation are realized.

  6. Brain evolution and development: adaptation, allometry and constraint

    Science.gov (United States)

    Barton, Robert A.

    2016-01-01

    Phenotypic traits are products of two processes: evolution and development. But how do these processes combine to produce integrated phenotypes? Comparative studies identify consistent patterns of covariation, or allometries, between brain and body size, and between brain components, indicating the presence of significant constraints limiting independent evolution of separate parts. These constraints are poorly understood, but in principle could be either developmental or functional. The developmental constraints hypothesis suggests that individual components (brain and body size, or individual brain components) tend to evolve together because natural selection operates on relatively simple developmental mechanisms that affect the growth of all parts in a concerted manner. The functional constraints hypothesis suggests that correlated change reflects the action of selection on distributed functional systems connecting the different sub-components, predicting more complex patterns of mosaic change at the level of the functional systems and more complex genetic and developmental mechanisms. These hypotheses are not mutually exclusive but make different predictions. We review recent genetic and neurodevelopmental evidence, concluding that functional rather than developmental constraints are the main cause of the observed patterns. PMID:27629025

  7. Development of a Mediterranean diet score adapted to Japan and its relation to obesity risk

    Directory of Open Access Journals (Sweden)

    Masao Kanauchi

    2016-11-01

    Full Text Available Background: The Mediterranean diet (MD is well known as a healthy diet that protects against several chronic diseases. However, there is no appropriate and easy index to assess adherence to the MD pattern in Japan. Objective: The aim of this study was to develop a novel instrument to measure MD adherence adapted to a Japanese diet and to examine its association with overweight/obesity risk. Methods: A cross-sectional nutritional survey provided the data for construction of a novel MD score. In total, 1,048 subjects who were employees and university students, aged 18–68 years (645 men and 403 women, completed a 58-item brief-type self-administered dietary history questionnaire. We constructed a Japanese-adapted MD score (jMD score focusing on 13 components. Adherence to the jMD was categorized as low (score 0–4, moderate (5–7, or high (8–13. Results: Men had higher jMD scores than women, and adherence to the jMD score increased with age. Only 11.6% of subjects showed high adherence to the jMD, whereas 29.6% showed low adherence. A higher jMD adherence was associated with a higher intake of favorable nutrients with the exception of salt. The jMD adherence was significantly associated with a reduced likelihood of having overweight/obesity for the highest category compared with lowest category (odds ratio [OR] 0.50, 95% confidence interval [CI] 0.30–0.85, p-trend=0.017 after adjusting for age, sex, smoking, physical activity, alcohol intake, and hypertension. A two-point increment in jMD score was related to a reduced likelihood of having overweight/obesity with an odds ratio of 0.76 (95% CI 0.65–0.90, p=0.002. Conclusions: Our novel jMD score confirmed reasonable associations with nutrient intakes, and higher MD adherence was associated with a lower prevalence of overweight/obesity.

  8. Development of a Mediterranean diet score adapted to Japan and its relation to obesity risk.

    Science.gov (United States)

    Kanauchi, Masao; Kanauchi, Kimiko

    2016-01-01

    The Mediterranean diet (MD) is well known as a healthy diet that protects against several chronic diseases. However, there is no appropriate and easy index to assess adherence to the MD pattern in Japan. The aim of this study was to develop a novel instrument to measure MD adherence adapted to a Japanese diet and to examine its association with overweight/obesity risk. A cross-sectional nutritional survey provided the data for construction of a novel MD score. In total, 1,048 subjects who were employees and university students, aged 18-68 years (645 men and 403 women), completed a 58-item brief-type self-administered dietary history questionnaire. We constructed a Japanese-adapted MD score (jMD score) focusing on 13 components. Adherence to the jMD was categorized as low (score 0-4), moderate (5-7), or high (8-13). Men had higher jMD scores than women, and adherence to the jMD score increased with age. Only 11.6% of subjects showed high adherence to the jMD, whereas 29.6% showed low adherence. A higher jMD adherence was associated with a higher intake of favorable nutrients with the exception of salt. The jMD adherence was significantly associated with a reduced likelihood of having overweight/obesity for the highest category compared with lowest category (odds ratio [OR] 0.50, 95% confidence interval [CI] 0.30-0.85, p-trend=0.017) after adjusting for age, sex, smoking, physical activity, alcohol intake, and hypertension. A two-point increment in jMD score was related to a reduced likelihood of having overweight/obesity with an odds ratio of 0.76 (95% CI 0.65-0.90, p=0.002). Our novel jMD score confirmed reasonable associations with nutrient intakes, and higher MD adherence was associated with a lower prevalence of overweight/obesity.

  9. Radiation protection concepts review with an adapted quiz commercial game; Relembrando os conceitos de radioprotecao por meio de um jogo comercial adaptado

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues Junior, Ary de Araujo [Empresa Brasileira de Radiacoes Ltda. (EMBRARAD), Cotia, SP (Brazil)]. E-mail: aryarj@ig.com.br

    2002-07-01

    Before a new employee starts working at EMBRARAD under a large irradiation operator supervision, he has to attend the first radiation protection training. After that all radiation protection subjects are revised every six months. In that half-yearly training the employees are chosen randomly to explain radiation protection subjects to other participants under an instructor supervision. After some years attending the same training, employees do not have motivation to participate in this kind of periodic event due to the same issues covered. Therefore something should be made to revival their interest and motivation to take part in this periodic training. The way chose was adapted a commercial game to revised radiation protection subjects and included it in the periodic training. The game was well accepted by the employees, it caused a competition among them because everybody wanted to win the game and consequently stimulated them to study. (author)

  10. MORPHOLOGICAL DEVELOPMENT OF A NATURE-LIKE BANK PROTECTION

    Institute of Scientific and Technical Information of China (English)

    Silke WIEPRECHT

    2001-01-01

    In the context of the planned near - natural restructuring of the river Isar in the southern part of Munich the results which were obtained from the 2d hydrodynamic model had to be validated by a physical model.In addition to the hydraulics the investigations of the physical model are including the shape and stability of the redesigned gently sloping banks, the formation and dynamics of aggradation zones, the stability of islands as well as the structure of the ramps. This paper is mainly focused on a special kind of bank protection which is hidden in the flood plains. Thus the safety of the dams is guaranteed as well as an area for natural morphological dynamic processes is available. The model also proved to be a very useful public relations tool for this spectacular project.

  11. Talent Development Environment and Workplace Adaptation: The Mediating Effects of Organisational Support

    Science.gov (United States)

    Kunasegaran, Mageswari; Ismail, Maimunah; Rasdi, Roziah Mohd; Ismail, Ismi Arif; Ramayah, T.

    2016-01-01

    Purpose: This study aims to examine the relationship between talent development environment (TDE) variables of job focus and long-term development with the workplace adaptation (WA) of Malaysian professional returnees as mediated by the organisational support. Design/methodology/approach: A total of 130 respondents who are Malaysian professional…

  12. Adaptation to climate extremes in developing countries : the role of education

    OpenAIRE

    Blankespoor, Brian; Dasgupta, Susmita; Laplante, Benoit; Wheeler, David

    2010-01-01

    Global climate models predict a rise in extreme weather in the next century. To better understand future interactions among adaptation costs, socioeconomic development, and climate change in developing countries, observed losses of life from floods and droughts during 1960-2003 are modeled using three determinants: weather events, income per capita, and female education. The analysis revea...

  13. Adaptive urban development : a symbiosis between cities on land and water in the 21st century

    NARCIS (Netherlands)

    Graaf, Rutger de

    2012-01-01

    Adaptive urban development is the design, construction and continuing evolution of urban areas to anticipate and react to changes in the environment and society. These changes include both processes within the city itself and external developments. It is expected that until 2100 a total of 5 billion

  14. A Struggle for Reconciliation of Development and Climate Protection

    CERN Document Server

    Costa, Luís; Kropp, Jürgen P

    2010-01-01

    Although developing countries are called to participate on the efforts of reducing CO2 emissions in order to avoid dangerous climate change, the implications of CO2 reduction targets in human development standards of developing countries remain a matter of debate. We show the existence of a positive and - time dependent correlation between the Human Development Index (HDI) and per capita CO2 emissions from fossil fuel combustion. Based on this empirical relation and three population scenarios extracted from the Millennium Ecosystem Assessment report, we calculate for the first time the cumulative CO2 emissions necessary for developing countries to achieve particular HDI thresholds. If current demographic and development trends are maintained, we estimate that by 2050 around 85% of the world's population will live in countries with high HDI (above 0.8) as defined in the United Nations Human Development Report. In particular, we estimate that at least 300Gt of cumulative CO2 emissions between 2000 and 2050 are ...

  15. Development directions of the global climate protection law; Die Entwicklungslinien des globalen Klimaschutzrechts

    Energy Technology Data Exchange (ETDEWEB)

    Richter, Katharina [Bochum Univ. (Germany)

    2014-07-01

    The contribution on development directions of the global climate protection law covers the origination process of the Kyoto protocol, the precise form of the Kyoto protocol, the climate protection regime afterwards: Montreal 2005 - implementation-improvement-innovation, Nairobi 2006 - climatic change very close, Bali 2007 - roadmap, Posen 2008 - intermediate step, Copenhagen 2009 - stagnancy, Cancun 2010 - comeback, Durban 2011 - gleam of hope, Doha 2012 - minimum compromise, Warsaw 2013 - hope. The last chapter discusses the fundamental problems and perspectives of the climate protection laws.

  16. Physically distributed learning: adapting and reinterpreting physical environments in the development of fraction concepts.

    Science.gov (United States)

    Martin, Taylor; Schwartz, Daniel L

    2005-07-08

    Five studies examined how interacting with the physical environment can support the development of fraction concepts. Nine- and 10-year-old children worked on fraction problems they could not complete mentally. Experiments 1 and 2 showed that manipulating physical pieces facilitated children's ability to develop an interpretation of fractions. Experiment 3 demonstrated that when children understood a content area well, they used their interpretations to repurpose many environments to support problem solving, whereas when they needed to learn, they were prone to the structure of the environment. Experiments 4 and 5 examined transfer after children had learned by manipulating physical pieces. Children who learned by adapting relatively unstructured environments transferred to new materials better than children who learned with "well-structured" environments that did not require equivalent adaptation. Together, the findings reveal that during physically distributed learning, the opportunity to adapt an environment permits the development of new interpretations that can advance learning.

  17. Tools influencing on business development and population's social protection

    Directory of Open Access Journals (Sweden)

    Susanna Alieva

    2009-10-01

    Full Text Available The paper raises the issue how to develop public policy instruments that could efficiently target bothdevelopment of entrepreneurship and strengthening of social safety of workers.

  18. Water governance: learning by developing adaptive capacity to incorporate climate variability and change.

    Science.gov (United States)

    Kashyap, A

    2004-01-01

    There is increasing evidence that global climate variability and change is affecting the quality and availability of water supplies. Integrated water resources development, use, and management strategies, represent an effective approach to achieve sustainable development of water resources in a changing environment with competing demands. It is also a key to achieving the Millennium Development Goals. It is critical that integrated water management strategies must incorporate the impacts of climate variability and change to reduce vulnerability of the poor, strengthen sustainable livelihoods and support national sustainable development. UNDP's strategy focuses on developing adaptation in the water governance sector as an entry point within the framework of poverty reduction and national sustainable development. This strategy aims to strengthen the capacity of governments and civil society organizations to have access to early warning systems, ability to assess the impact of climate variability and change on integrated water resources management, and developing adaptation intervention through hands-on learning by undertaking pilot activities.

  19. Development of a respiratory protection survey instrument for occupational health nurses: an educational project.

    Science.gov (United States)

    Taormina, Deborah; Burgel, Barbara J

    2013-02-01

    The Institute of Medicine (2011) report Occupational Health Nurses and Respiratory Protection: Improving Education and Training outlined seven recommendations to improve the competency of occupational health nurses in respiratory protection. An advisory group was convened in December 2011, with stakeholder representation from the Centers for Disease Control and Prevention/National Institute for Occupational Safety and Health/National Personal Protective Technology Laboratory, American Association of Occupational Health Nurses, Inc., American Board for Occupational Health Nurses, Inc., Association of Occupational Health Professionals in Healthcare, American Nurses Association, and Institute of Medicine Standing Committee on Personal Protective Equipment for Workplace Safety and Health. The initial work of the advisory group included developing and administering a survey to assess current occupational health nurse roles and responsibilities relevant to respiratory protection. Development of the survey was led by a master's student and advisor who worked with the advisory group. The process of tool development and preliminary findings are presented in this article.

  20. Beyond cost-benefit: developing a complete toolkit for adaptation decisions

    Energy Technology Data Exchange (ETDEWEB)

    Berger, Rachel; Chambwera, Muyeye

    2010-06-15

    Cost-benefit analysis has important uses – and crucial blind spots. It represents only one of several economic tools that can be used to assess options for adapting to climate change in developing countries. The Nairobi Work Programme would best serve governments by considering not just cost-benefit approaches, but the entire range of tools. By developing a 'toolkit' that helps users choose from a variety of evaluation methods, we can support adaptation decisions that promote equity, put local people in control and allow for dynamic responses to climate change as it unfolds.

  1. Microstructural development of protective Al2O3 scales

    Science.gov (United States)

    Smialek, J. L.

    1984-01-01

    Microstructural characteristics of Al2O3 scales grown as protective coatings on NiCrAl alloys used in jet engines are described. The alloys were pure or doped with 0.3 percent Zr or Y and oxidized in 1 atm air at 1100 C for 0.1, 1 or 20.0 hr. The scales were then examined under a microscope. Transient epitaxial scales, formed during the 0.1 hr treatment and containing Ni, Cr and Al, consisted of a mosaic of subgrains and precipitates of different phases. The Y and Zr dopants had no effect on the nucleation site locations. The appearance of intergranular porosity at 0.1 hr was exacerbated after the 1 hr treatment. A bimodal void distribution appeared after 20 hr, when no porosity was evident. The detection of local areas of preferred orientation is taken as a spur to further studies of scale growth to gain control of the grain size or even to produce single crystal scales.

  2. Challenges to the Future Development of Iran's Protected Areas System

    Science.gov (United States)

    Kolahi, Mahdi; Sakai, Tetsuro; Moriya, Kazuyuki; Makhdoum, Majid F.

    2012-10-01

    Since the 1950s, there has been a continuous increase in the number and coverage of protected areas (PAs) in Iran, and in total 253 PAs have been declared that cover 10.12 % of the country's area. This paper reviews literature addressing Iran's PAs, examines what is known about them, highlights the challenges and lessons learned, and identifies areas where more research is needed. The PA system in Iran is criticized because of (1) shortages of manpower, equipment, and financial resources; (2) de jure PAs that are often implemented as de facto reserves; (3) lack of national biodiversity indicators and objective monitoring processes; and (4) limited public participation and conflict between people over PAs. To improve, Iran's PAs system needs to be realistically supported by policies and planning instruments. In addition, the implementation of active management to restore habitat, increase education and awareness, shift practices towards the guidelines of international organizations, build capacity, and improve management and co-management by local communities needs to occur.

  3. Legal Protection To The Infotainment Of Press Development In Indonesia

    Directory of Open Access Journals (Sweden)

    Anwar Fuadi

    2015-08-01

    Full Text Available Abstract In the socio-political life the press has become an integral part in democratic life. The press has become one of the means for citizens to bring their thoughts and opinions. Nowadays there is a tendency to increase the quantity of press publications sharp but not accompanied by a statement of the quality of journalism. The objective of this research is to understand the essence of the infotainment liability as a mass media in order to construct a freedom of the press principle which has legitimacy within the legal system of the press in Indonesia. The type of research used in this paper is normative research or also known as doctrinal research by reviewing the legal protection to the infotainment as a mass media in Indonesia. The outcomes of the research indicate that the role of infotainment in the legal system of the press in Indonesia refers to the legal construction of institutional and infotainment organizers itself. Legal liability of Infotainment essentially can be seen from the press obligations stipulated in the Law No. 40 of 1999 regarding the Press Law No. 32 of 2002 regarding Broadcasting as well as the Journalists Code of Ethics which support freedom of the press and expression.

  4. Adaptation: Needs, Financing and Institutions

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Richard J.T.; Kartha, Sivan; Persson, Aasa; Watkiss, Paul; Ackerman, Frank; Downing, Thomas E.; Kjellen, Bo; Schipper, Lisa (Stockholm Environment Institute, Stockholm (SE))

    2008-07-01

    Regardless of the efforts put into mitigation, some impacts of climate change are already unavoidable. Adaptation to climate change has therefore become a key component of domestic climate policy, along with mitigation. Adaptation has also become key to the success of global climate policy. Without an agreement on supporting adaptation in developing countries, there will be no agreement on mitigation. Strong mitigation efforts make it more likely that adaptation will be effective and affordable. The world cannot rely on adaptation alone: it would eventually lead to a level of climate change to which adaptation is no longer feasible. Government action is needed to create an enabling environment for adaptation. This includes removing existing financial, legal, institutional and knowledge barriers to adaptation, and strengthening the capacity of people and organisations to adapt. The success of adaptation relies on the success of development, and vice versa. Poverty reduction, good governance, education, environmental protection, health and gender equality all contribute to adaptive capacity. Substantially more money is needed to support adaptation in developing countries. Current levels of funding will soon have to be scaled up by two orders of magnitude (from US$ hundreds of million to US$ tens of billion per year). An agreement on adaptation in Copenhagen in 2009 will need to include concrete steps towards a strengthened knowledge base for adaptation, substantially more funding for developing countries, and enhanced adaptation planning and implementation at the national level. Recommendations: Developed countries should accept a transparent, principle-based allocation of responsibility for adaptation funding, resulting in adequate, new and additional money to support adaptation programmes in developing countries. Levies on carbon market transactions and auctioning emission permits are two existing mechanisms of generating new and additional funds consistent with

  5. Media representations of early human development: protecting, feeding and loving the developing brain.

    Science.gov (United States)

    O'Connor, Cliodhna; Joffe, Helene

    2013-11-01

    The public profile of neurodevelopmental research has expanded in recent years. This paper applies social representations theory to explore how early brain development was represented in the UK print media in the first decade of the 21st century. A thematic analysis was performed on 505 newspaper articles published between 2000 and 2010 that discussed early brain development. Media coverage centred around concern with 'protecting' the prenatal brain (identifying threats to foetal neurodevelopment), 'feeding' the infant brain (indicating the patterns of nutrition that enhance brain development) and 'loving' the young child's brain (elucidating the developmental significance of emotionally nurturing family environments). The media focused almost exclusively on the role of parental action in promoting optimal neurodevelopment, rarely acknowledging wider structural, cultural or political means of supporting child development. The significance of parental care was intensified by deterministic interpretations of critical periods, which implied that inappropriate parental input would produce profound and enduring neurobiological impairments. Neurodevelopmental research was also used to promulgate normative judgements concerning the acceptability of certain gender roles and family contexts. The paper argues that media representations of neurodevelopment stress parental responsibility for shaping a child's future while relegating the contributions of genetic or wider societal factors, and examines the consequences of these representations for society and family life.

  6. Adaptive Software Development supported by an Automated Process: a Reference Model

    Directory of Open Access Journals (Sweden)

    AFFONSO, F. J.

    2013-12-01

    Full Text Available This paper presents a reference model as an automated process to assist the adaptive software development at runtime, also known as Self-adaptive Systems (SaS at runtime. This type of software has specific characteristics in comparison to traditional one, since it allows that changes (structural or behavioral to be incorporated at runtime. Automated processes have been used as a feasible solution to conduct software adaptation at runtime by minimizing human involvement (developers and speeding up the execution of tasks. In parallel, reference models have been used to aggregate knowledge and architectural artifacts, since they capture the systems essence in specific domains. However, presently no there is reference model based on reflection for the automation of software adaptation at runtime. In this scenario, this paper presents a reference model based on reflection, as an automated process, for the development of software systems that require adaptation at runtime. To show the applicability of the model, a case study was conducted and a good perspective to efficiently contribute to the area of SaS has been obtained.

  7. The Environmental Right as a Human Right: Scientific Development and the Protection of Rights

    Institute of Scientific and Technical Information of China (English)

    ZHAN ZHONGLE

    2011-01-01

    @@ As environmental issues are attracting domestic and international attention,protection of environmental rights is becoming increasingly important in human rights affairs.Environmental protection involves economic development and social harmony, influences the maintenance and complete realization of people's rights to health, property and life, and is even related to the future existence of the whole human society.

  8. Development and Verification of Unstructured Adaptive Mesh Technique with Edge Compatibility

    Science.gov (United States)

    Ito, Kei; Kunugi, Tomoaki; Ohshima, Hiroyuki

    In the design study of the large-sized sodium-cooled fast reactor (JSFR), one key issue is suppression of gas entrainment (GE) phenomena at a gas-liquid interface. Therefore, the authors have been developed a high-precision CFD algorithm to evaluate the GE phenomena accurately. The CFD algorithm has been developed on unstructured meshes to establish an accurate modeling of JSFR system. For two-phase interfacial flow simulations, a high-precision volume-of-fluid algorithm is employed. It was confirmed that the developed CFD algorithm could reproduce the GE phenomena in a simple GE experiment. Recently, the authors have been developed an important technique for the simulation of the GE phenomena in JSFR. That is an unstructured adaptive mesh technique which can apply fine cells dynamically to the region where the GE occurs in JSFR. In this paper, as a part of the development, a two-dimensional unstructured adaptive mesh technique is discussed. In the two-dimensional adaptive mesh technique, each cell is refined isotropically to reduce distortions of the mesh. In addition, connection cells are formed to eliminate the edge incompatibility between refined and non-refined cells. The two-dimensional unstructured adaptive mesh technique is verified by solving well-known lid-driven cavity flow problem. As a result, the two-dimensional unstructured adaptive mesh technique succeeds in providing a high-precision solution, even though poor-quality distorted initial mesh is employed. In addition, the simulation error on the two-dimensional unstructured adaptive mesh is much less than the error on the structured mesh with a larger number of cells.

  9. Ohio Uses Wetlands Program Development Grants to Protect Wetlands

    Science.gov (United States)

    The wetland water quality standards require the use of ORAM score to determine wetland quality. OEPA has also used these tools to evaluate wetland mitigation projects, develop performance standards for wetland mitigation banks and In Lieu Fee programs an.

  10. Adapting and Using Scrum in a Software Research and Development Laboratory

    Directory of Open Access Journals (Sweden)

    LIMA, I. R.

    2012-06-01

    Full Text Available Agile software development has gained importance in the industry because of its approach on the issues of human agility and return on investment. This paper shows how Scrum agile software project management methodology has been deployed and adapted to the model of software project management of a research and development laboratory. As a result of this deployment, experiences and lessons learned in seven real projects developed by the authors are reported.

  11. Development of Individualized Mechatronic Products - Rapid Adaptation of Product Properties Due To Individual Customer Demands

    OpenAIRE

    Baumberger, Chr.;Lindemann, U.;Pulm, U.

    2017-01-01

    Mass Customization in the scope of product development means that a product will be developed (and manufactured later on) those properties exactly meet specific customer wishes and requirements. Likewise the concept of Mass Customization is associated with a lot of problems as well, especially concerning late product changes and the actual process of adapting product design properties to specific customer requirements. Without changing corresponding development processes and methods satisfact...

  12. Socio-economic vulnerability of coastal communities in southern Thailand: the development of adaptation strategies

    Science.gov (United States)

    Willroth, P.; Massmann, F.; Wehrhahn, R.; Revilla Diez, J.

    2012-08-01

    The tsunami of December 2004 impacted large areas of Thailand's coastline and caused severe human and economic losses. The recovery period revealed differences in the vulnerabilities of communities affected. An understanding of the causal factors of vulnerability is crucial for minimising the negative effects of future threats and developing adaptive capacities. This paper analyses the vulnerabilities and the development of adaptation strategies in the booming tourist area of Khao Lak and in the predominantly fishing and agricultural area of Ban Nam Khem through a comprehensive vulnerability framework. The results show that social networks played a crucial role in coping with the disaster. Social cohesion is important for strengthening the community and developing successful adaptation strategies. The development of tourism and the turning away from traditional activities have a significant positive influence on the income situation, but create a dependency on a single business sector. It could be shown that households generating their income in the tourism sector were vulnerable unless they had diversified their income previously. Income diversification decreased the vulnerability in the study areas. Adaptation strategies and processes developed in the aftermath clearly address these issues.

  13. Socio-economic vulnerability of coastal communities in southern Thailand: the development of adaptation strategies

    Directory of Open Access Journals (Sweden)

    P. Willroth

    2012-08-01

    Full Text Available The tsunami of December 2004 impacted large areas of Thailand's coastline and caused severe human and economic losses. The recovery period revealed differences in the vulnerabilities of communities affected. An understanding of the causal factors of vulnerability is crucial for minimising the negative effects of future threats and developing adaptive capacities. This paper analyses the vulnerabilities and the development of adaptation strategies in the booming tourist area of Khao Lak and in the predominantly fishing and agricultural area of Ban Nam Khem through a comprehensive vulnerability framework. The results show that social networks played a crucial role in coping with the disaster. Social cohesion is important for strengthening the community and developing successful adaptation strategies. The development of tourism and the turning away from traditional activities have a significant positive influence on the income situation, but create a dependency on a single business sector. It could be shown that households generating their income in the tourism sector were vulnerable unless they had diversified their income previously. Income diversification decreased the vulnerability in the study areas. Adaptation strategies and processes developed in the aftermath clearly address these issues.

  14. Danish Mortgage Finance, Property Rights Protection and Economic Development

    DEFF Research Database (Denmark)

    Haldrup, Karin

    The Danish mortgage finance system is attracting much international attention due to its simple, robust and efficient securitization principle, the balance principle. Housing finance experts consider how the model can be introduced in other countries to overcome shortcomings in previous mortgage...... systems (e.g., in the US) or to alleviate the gigantic unmet needs for housing finance around the world. In support of such efforts the research challenge was the development of a methodology for screening of readiness for transplanting this financing system to other countries. However, the development...... of screening methods for assessing the readiness for such transplantation depends on a deeper understanding of three large domains: A) Mortgage Finance, B) Cadastre and Land Registration; and C) Economic Development; and the interrelations between these three areas. In particular the thesis has focused...

  15. Danish Mortgage Finance, Property Rights Protection and Economic Development

    DEFF Research Database (Denmark)

    Haldrup, Karin

    The Danish mortgage finance system is attracting much international attention due to its simple, robust and efficient securitization principle, the balance principle. Housing finance experts consider how the model can be introduced in other countries to overcome shortcomings in previous mortgage...... systems (e.g., in the US) or to alleviate the gigantic unmet needs for housing finance around the world. In support of such efforts the research challenge was the development of a methodology for screening of readiness for transplanting this financing system to other countries. However, the development...... of screening methods for assessing the readiness for such transplantation depends on a deeper understanding of three large domains: A) Mortgage Finance, B) Cadastre and Land Registration; and C) Economic Development; and the interrelations between these three areas. In particular the thesis has focused...

  16. Recent Developments on Autonomous Corrosion Protection Through Encapsulation

    Science.gov (United States)

    Li, W.; Buhrow, J. W.; Calle, L. M.; Gillis, M.; Blanton, M.; Hanna, J.; Rawlins, J.

    2015-01-01

    This paper concerns recent progress in the development of a multifunctional smart coating, based on microencapsulation, for the autonomous detection and control of corrosion. Microencapsulation has been validated and optimized to incorporate desired corrosion control functionalities, such as early corrosion detection and inhibition, through corrosion-initiated release of corrosion indicators and inhibitors, as well as self-healing agent release triggered by mechanical damage. While proof-of-concept results have been previously reported, more recent research and development efforts have concentrated on improving coating compatibility and synthesis procedure scalability, with a targeted goal of obtaining easily dispersible pigment-grade type microencapsulated materials. The recent progress has resulted in the development of pH-sensitive microparticles as a corrosion-triggered delivery system for corrosion indicators and inhibitors. The synthesis and early corrosion indication results obtained with coating formulations that incorporate these microparticles are reported. The early corrosion indicating results were obtained with color changing and with fluorescent indicators.

  17. Recent Developments on Microencapsulation for Autonomous Corrosion Protection

    Science.gov (United States)

    Calle, Luz M.; Li, Wenyan; Buhrow, Jerry W.; Fitzpatrick, Lilliana; Jolley, Scott T.; Surma, Jan M.; Pearman, Benjamin P.; Zhang, Xuejun

    2014-01-01

    This work concerns recent progress in the development of a multifunctional smart coating based on microencapsulation for the autonomous control of corrosion. Microencapsulation allows the incorporation of desired corrosion control functionalities, such as early corrosion detection and inhibition through corrosion controlled release of corrosion indicators and inhibitors, as well as self-healing agent release when mechanical damage occurs.While proof-of-concept results have been reported previously, more recent efforts have been concentrated in technical developments to improve coating compatibility, synthesis procedure scalability, as well as fine tuning the release property of encapsulated active agents.

  18. Balancing housing growth and land conservation: Conservation development preserves private lands near protected areas

    Science.gov (United States)

    Miranda H. Mockrin; Sarah E. Reed; Liba Pejchar; Jessica Salo

    2017-01-01

    Housing development has emerged as a primary driver of land-use change around the world. In the United States, there is particular concern about low-density residential development on rural lands, which often occurs in places with abundant natural amenities. Conservation development (CD), housing development that incorporates protected open space, has emerged as a tool...

  19. Air-adapted Methanosarcina acetivorans shows high methane production and develops resistance against oxygen stress.

    Directory of Open Access Journals (Sweden)

    Ricardo Jasso-Chávez

    Full Text Available Methanosarcina acetivorans, considered a strict anaerobic archaeon, was cultured in the presence of 0.4-1% O2 (atmospheric for at least 6 months to generate air-adapted cells; further, the biochemical mechanisms developed to deal with O2 were characterized. Methane production and protein content, as indicators of cell growth, did not change in air-adapted cells respect to cells cultured under anoxia (control cells. In contrast, growth and methane production significantly decreased in control cells exposed for the first time to O2. Production of reactive oxygen species was 50 times lower in air-adapted cells versus control cells, suggesting enhanced anti-oxidant mechanisms that attenuated the O2 toxicity. In this regard, (i the transcripts and activities of superoxide dismutase, catalase and peroxidase significantly increased; and (ii the thiol-molecules (cysteine + coenzyme M-SH + sulfide and polyphosphate contents were respectively 2 and 5 times higher in air-adapted cells versus anaerobic-control cells. Long-term cultures (18 days of air-adapted cells exposed to 2% O2 exhibited the ability to form biofilms. These data indicate that M. acetivorans develops multiple mechanisms to contend with O2 and the associated oxidative stress, as also suggested by genome analyses for some methanogens.

  20. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development

    NARCIS (Netherlands)

    Berbeé, J.F.P.; Boon, M.R.; Khedoe, P.P.S.J.; Bartelt, A.; Schlein, C.; Worthmann, A.; Kooijman, S.; Hoeke, G.; Mol, I.M.; John, C.; Jung, C.; Vazirpanah, N.; Brouwers, L.P.J.; Gordts, P.L.S.M.; Esko, J.D.; Hiemstra, P.S.; Havekes, L.M.; Scheja, L.; Heeren, J.; Rensen, P.C.N.

    2015-01-01

    Brown adipose tissue (BAT) combusts high amounts of fatty acids, thereby lowering plasma triglyceride levels and reducing obesity. However, the precise role of BAT in plasma cholesterol metabolism and atherosclerosis development remains unclear. Here we show that BAT activation by b3-adrenergic rece

  1. Protection of minority interest and the development of security markets

    NARCIS (Netherlands)

    Modigliani, F.; Perotti, E.C.

    1997-01-01

    While excessive regulation is an obstacle to the development of financial markets, we argue that lack of basic rules or poorly enforced regulation may explain the relative importance across countries of banking and security markets in financing firms. A selective or arbitrary enforcement transforms

  2. Climate protection and sustainable economy. For a new development political mission statement; Klimaschutz und nachhaltiges Wirtschaften. Fuer ein neues entwicklungspolitisches Leitbild

    Energy Technology Data Exchange (ETDEWEB)

    Kofler, Baerbel; Netzer, Nina (eds.)

    2011-11-15

    The book under consideration is devoted to climate protection and sustainable economy. It consists of the following contributions: (1) Climate protection and development policy - New allies in the fight against poverty? (B. Kofler); (2) In preparation for a wormer world - Adjustment to the climatic change using local resources (A. Schroeder); (3) Sustainable economy today - a development political consideration (H.-J. Luhmann); (4) The Clean Development Mechanism - No-Win instead of Win-Win for developing countries?; (5) New market based mechanisms for improving the climate protection in developing countries (K. Wentrup); (6) Global emission trading: market-economy instruments for a development-oriented climate policy? (S. Fischer); (7) The policy is needed - Central strategies for combating climatic change (R. Guenther); (8) Technology transfer: Political controversies, successes and problems of implementation (C. Gerstetter); (9) REDDplus - Forest protection as a chance for development and poverty reduction (K. Gerber); (10) What is climate justice? From the principle to political practice (T. Hirsch); (11) How much are 100 Billion Us-Dollar? Financing of climate protection between adequacy and creative bookkeeping (W. Sterk); (12) No money, no fun - Climate change financing has to be made more concrete (F. Schwabe); (13) Human rights - Common struggle against the climatic change (T. Rathgeber); (14) Climate change adaptation - Handling extreme events and damages: 'Loss and damage' (T. Hirsch); (15) Rio 2012 and the reform of the international environment governance (N. Simon).

  3. Research on the sustainable development of ecotourism in protected areas: a review

    Institute of Scientific and Technical Information of China (English)

    Cheng Zhenyu

    2009-01-01

    Due to the unique function of protected areas in species and nature resources conservation, sustainability has become the primary consideration in the development of ecotourism in protected areas.This paper focuses on this issue, and reviews the current literatures in this field, tries to give a comprehensive review which can also be organized in logical sense, classifies three major paradigms about the current research:research on the development of ecotourism in protected areas, research on the external indicators which affect the sustainability of ecotourism in protected areas, researches on the assessment of sustainability of ecotourism in protected areas, and finally points out that the further study in this field must be carried out by inter-disciplines, such as cultural economics and ecological economics.

  4. Regulation Of Nf=kb And Mnsod In Low Dose Radiation Induced Adaptive Protection Of Mouse And Human Skin Cells

    Energy Technology Data Exchange (ETDEWEB)

    Jian Li

    2012-11-07

    A sampling of publications resulting from this grant is provided. One is on the subject of NF-κB-Mediated HER2 Overexpression in Radiation-Adaptive Resistance. Another is on NF-κB-mediated adaptive resistance to ionizing radiation.

  5. Early Vocabulary Development in Deaf Native Signers: A British Sign Language Adaptation of the Communicative Development Inventories

    Science.gov (United States)

    Woolfe, Tyron; Herman, Rosalind; Roy, Penny; Woll, Bencie

    2010-01-01

    Background: There is a dearth of assessments of sign language development in young deaf children. This study gathered age-related scores from a sample of deaf native signing children using an adapted version of the MacArthur-Bates CDI (Fenson et al., 1994). Method: Parental reports on children's receptive and expressive signing were collected…

  6. Adapting to the Online Teaching Environment: Using Literature To Develop Experiential Exercises for International Management.

    Science.gov (United States)

    Rusinko, Cathy A.

    2003-01-01

    Proposes that literature may be a valuable tool in adapting teaching methods to the online environment, particularly developing experiential exercises, and in helping students become better international managers by building communication skills, team building skills, and contextual understanding of cultural diversity issues. Includes an example…

  7. Development of Computerized Adaptive Testing (CAT) for the EORTC QLQ-C30

    DEFF Research Database (Denmark)

    Petersen, Morten Aagaard; Grønvold, Mogens; on behalf of the EORTC Quality of Life Group

    2013-01-01

    The EORTC QLQ-C30 is one of the most widely used health-related quality of life (HRQOL) instruments globally. The Quality of Life Group is developing a new version of the EORTC QLQ-C30 questionnaire based on computerized adaptive testing (CAT). The new CAT instrument will measure the same HRQOL...

  8. Language, Reading, and Readability Formulas: Implications for Developing and Adapting Tests

    Science.gov (United States)

    Oakland, Thomas; Lane, Holly B.

    2004-01-01

    Issues pertaining to language and reading while developing and adapting tests are examined. Strengths and limitations associated with the use of readability formulas are discussed. Their use should be confined to paragraphs and longer passages, not items. Readability methods that consider both quantitative and qualitative variables and are…

  9. Opportunities to Develop Adaptive Expertise during Student Teaching Conferences: Identifying Barriers and Exploring Intersubjectivity

    Science.gov (United States)

    Soslau, Elizabeth Gayle

    2010-01-01

    Pupils' classrooms are highly variable and teachers have a difficult time addressing the broad range of students' needs in diverse contexts. Additionally, teachers are often not taught how to learn from their own teaching and develop adaptive teaching expertise, a necessary ability for educators in a constantly changing social world. The…

  10. A Learning Style Perspective to Investigate the Necessity of Developing Adaptive Learning Systems

    Science.gov (United States)

    Hwang, Gwo-Jen; Sung, Han-Yu; Hung, Chun-Ming; Huang, Iwen

    2013-01-01

    Learning styles are considered to be one of the factors that need to be taken into account in developing adaptive learning systems. However, few studies have been conducted to investigate if students have the ability to choose the best-fit e-learning systems or content presentation styles for themselves in terms of learning style perspective. In…

  11. The Development of Group Interaction Patterns: How Groups become Adaptive, Generative, and Transformative Learners

    Science.gov (United States)

    London, Manuel; Sessa, Valerie I.

    2007-01-01

    This article integrates the literature on group interaction process analysis and group learning, providing a framework for understanding how patterns of interaction develop. The model proposes how adaptive, generative, and transformative learning processes evolve and vary in their functionality. Environmental triggers for learning, the group's…

  12. Developing adaptive mobile support for crisis response in synthetic task environments

    NARCIS (Netherlands)

    Brake, G.M. te; Smets, N.J.J.M.

    2007-01-01

    This paper presents an experimental platform for the development and evaluation of mobile decision support for crisis response operations. Using a game-engine, synthetic task environments can be created in which coordination support and the usability of adaptive user interfaces for first responders

  13. Evaluation of a Physiologically Based Pharmacokinetic (PBPK) Model Used to Develop Health Protective Levels for Trichloroethylene

    Science.gov (United States)

    2017-02-28

    AFRL-RH-WP-TR-2017-0014 EVALUATION OF A PHYSIOLOGICALLY-BASED PHARMACOKINETIC (PBPK) MODEL USED TO DEVELOP HEALTH PROTECTIVE LEVELS FOR...Pharmacokinetic (PBPK) Model Used to Develop Health Protective Levels for Trichloroethylene 5a. CONTRACT NUMBER FA8650-15-2-6608 5b. GRANT...Anita Meyer, Army Corps of Engineers (CEHNC-EMS) and Shannon S. Garcia, AFCEC/CZTE for their efforts to obtain the required funding. The authors also

  14. An Overview of Recent Developments in Cognitive Diagnostic Computer Adaptive Assessments

    Directory of Open Access Journals (Sweden)

    Alan Huebner

    2010-01-01

    Full Text Available Cognitive diagnostic modeling has become an exciting new field of psychometric research. These models aim to diagnose examinees' mastery status of a group of discretely defined skills, or attributes, thereby providing them with detailed information regarding their specific strengths and weaknesses. Combining cognitive diagnosis with computer adaptive assessments has emerged as an important part of this new field. This article aims to provide practitioners and researchers with an introduction to and overview of recent developments in cognitive diagnostic computer adaptive assessments.

  15. Railway Development from the Aspect of Environmental Protection

    Directory of Open Access Journals (Sweden)

    Jasna Blašković Zavada

    2002-07-01

    Full Text Available General development of civilisation and constant growth ofpopulation have inevitably resulted in an increased volume oftraffic and energy consumption. One of the consequences isalso the adverse effect on the environment, i.e. people, climateand nature. Compming individual forms of transport, it may benoted that railway, as mass carrier in passenger and freight trafficplays a significant role and has great responsibility. Sincerailway represents a very convenient form of transport regardingboth power and ecology, it has to provide significant contributionto the passenger and freight transport in the future, in a waywhich is friendlier to the environment than most other forms oftransport.This work analyses the cun-ent and future role of railway inthe transportation of people and goods. It mentions the mostimportant strategic orientations in the railway development,that would render it competitive and attractive compared toroad and air traffic. Special emphasis is put on economic efficiency,ecological sustainability and social justice. The possibilitiesof reducing energy consumption, i.e. C02 emissions, aswell as reducing hannful exhaust gases of Diesel railway tractionvehicles are given special consideration.

  16. Developing measurement indices to enhance protection and resilience of critical infrastructure and key resources.

    Science.gov (United States)

    Fisher, Ronald E; Norman, Michael

    2010-07-01

    The US Department of Homeland Security (DHS) is developing indices to better assist in the risk management of critical infrastructures. The first of these indices is the Protective Measures Index - a quantitative index that measures overall protection across component categories: physical security, security management, security force, information sharing, protective measures and dependencies. The Protective Measures Index, which can also be recalculated as the Vulnerability Index, is a way to compare differing protective measures (eg fence versus security training). The second of these indices is the Resilience Index, which assesses a site's resilience and consists of three primary components: robustness, resourcefulness and recovery. The third index is the Criticality Index, which assesses the importance of a facility. The Criticality Index includes economic, human, governance and mass evacuation impacts. The Protective Measures Index, Resilience Index and Criticality Index are being developed as part of the Enhanced Critical Infrastructure Protection initiative that DHS protective security advisers implement across the nation at critical facilities. This paper describes two core themes: determination of the vulnerability, resilience and criticality of a facility and comparison of the indices at different facilities.

  17. Research Based on Distribution Network Adaptive-Protection When Doubly-Fed Unit Wind Farms Combine to Grid%基于双馈机组风电场并入网后的自适应保护

    Institute of Scientific and Technical Information of China (English)

    王飞; 郑日红; 段建东

    2012-01-01

    Accompanied with constantly development of wind power technology, the number of wind turbines as well as the capacity of single-machine has been increasing continually these resulting a higher capacity ratio supplied by wind farms to the system. Meanwhile because of the stochastic nature of wind speed and control difficult to stability the short circuit current feed by wind power station is also increasing. Thus, the study of distribution network protection cannot be neglected when the wind power plants merge in. Through the doubly-fed fan characteristic analysis it can be known the traditional protection methods can' t satisfy the requirement, so self-adaptive protection was introduced and then analyzed its principle. At last it can be drawn an inclusion that self-adaptive protection can be applied in distribution network protection when wind generators merge in.%随着风力发电技术的不断发展,风电机组数量及单机容量都在不断增加,这使得风电场对系统提供的容量比重增大;而且风速具有随机性,其控制也难以稳定,导致风场向系统提供的短路电流也在增大.那么随着风场大规模并网,对配电网的保护是不容忽视的.通过分析双馈风机特性及风机数学模型得知传统的继电保护已不能满足要求,为此引入了自适应保护,在剖析其原理的基础上论证了自适应保护可应用于并入风电场后的配电网的继电保护当中.

  18. Adaptive Behavior and Development of Infants and Toddlers with Williams Syndrome

    Directory of Open Access Journals (Sweden)

    Rebecca M. Kirchner

    2016-04-01

    Full Text Available Williams syndrome (WS is a neurodevelopmental disorder that causes deficits in adaptive behavior, difficulties eating and sleeping, cognitive delays, and delayed development. Although researchers have conducted characterizations of children and adults with WS, less is known about young children with this disorder. This study characterizes the developmental and adaptive behavior features of 16 infants and toddlers with WS aged 3 months - 5 years. Data for this project was obtained from 2007-2014, and includes parent report data and standardized developmental testing. Thirty-one percent (31.3% of parents reported that their infant/toddler with WS had sleeping problems and 58.3% reported feeding difficulties. Levels of adaptive behavior were in the Mildly Delayed range as measured by the Adaptive Behavior Assessment System, Second Edition. Self care skills such as feeding or dressing oneself were significantly weaker than skills needed to function in the community, such as recognizing his/her home or throwing away trash. The difficulty with self-care skills is hypothesized to be related to the reported difficulties with eating and sleeping. Motor skills were significantly lower than both cognitive and language skills on the Bayley Scales of Infant and Toddler Development, Third Edition. The current study highlights the need for early intervention in these young children across all areas of development, particularly in self-care skills.

  19. Protected Areas' Impacts on Brazilian Amazon Deforestation: Examining Conservation-Development Interactions to Inform Planning.

    Science.gov (United States)

    Pfaff, Alexander; Robalino, Juan; Herrera, Diego; Sandoval, Catalina

    2015-01-01

    Protected areas are the leading forest conservation policy for species and ecoservices goals and they may feature in climate policy if countries with tropical forest rely on familiar tools. For Brazil's Legal Amazon, we estimate the average impact of protection upon deforestation and show how protected areas' forest impacts vary significantly with development pressure. We use matching, i.e., comparisons that are apples-to-apples in observed land characteristics, to address the fact that protected areas (PAs) tend to be located on lands facing less pressure. Correcting for that location bias lowers our estimates of PAs' forest impacts by roughly half. Further, it reveals significant variation in PA impacts along development-related dimensions: for example, the PAs that are closer to roads and the PAs closer to cities have higher impact. Planners have multiple conservation and development goals, and are constrained by cost, yet still conservation planning should reflect what our results imply about future impacts of PAs.

  20. Protected Areas’ Impacts on Brazilian Amazon Deforestation: Examining Conservation – Development Interactions to Inform Planning

    Science.gov (United States)

    Pfaff, Alexander; Robalino, Juan; Herrera, Diego; Sandoval, Catalina

    2015-01-01

    Protected areas are the leading forest conservation policy for species and ecoservices goals and they may feature in climate policy if countries with tropical forest rely on familiar tools. For Brazil's Legal Amazon, we estimate the average impact of protection upon deforestation and show how protected areas’ forest impacts vary significantly with development pressure. We use matching, i.e., comparisons that are apples-to-apples in observed land characteristics, to address the fact that protected areas (PAs) tend to be located on lands facing less pressure. Correcting for that location bias lowers our estimates of PAs’ forest impacts by roughly half. Further, it reveals significant variation in PA impacts along development-related dimensions: for example, the PAs that are closer to roads and the PAs closer to cities have higher impact. Planners have multiple conservation and development goals, and are constrained by cost, yet still conservation planning should reflect what our results imply about future impacts of PAs. PMID:26225922

  1. Adapting developing country epidemiological assessment techniques to improve the quality of health needs assessments in developed countries

    Directory of Open Access Journals (Sweden)

    Handy Deirdre

    2005-04-01

    Full Text Available Abstract Background We were commissioned to carry out three health assessments in urban areas of Dublin in Ireland. We required an epidemiologically robust method that could collect data rapidly and inexpensively. We were dealing with inadequate health information systems, weak planning data and a history of inadequate recipient involvement in health service planning. These problems had also been identified by researchers carrying out health assessments in developing countries. This paper reports our experience of adapting a cluster survey model originally developed by international organisations to assess community health needs and service coverage in developing countries and applying our adapted model to three urban areas in Dublin, Ireland Methods We adapted the model to control for socio-economic heterogeneity, to take account of the inadequate population list, to ensure a representative sample and to account for a higher prevalence of degenerative and chronic diseases. We employed formal as well as informal communication methods and adjusted data collection times to maximise participation. Results The model we adapted had the capacity to ascertain both health needs and health care delivery needs. The community participated throughout the process and members were trained and employed as data collectors. The assessments have been used by local health boards and non-governmental agencies to plan and deliver better or additional services. Conclusion We were able to carry out high quality health needs assessments in urban areas by adapting and applying a developing country health assessment method. Issues arose relating to health needs assessment as part of the planning cycle and the role of participants in the process.

  2. Development of vaccines against Plasmodium falciparum malaria: taking lessons from naturally acquired protective immunity

    DEFF Research Database (Denmark)

    Hviid, Lars

    2007-01-01

    The acquisition of substantial anti-malarial protection in people naturally exposed to P. falciparum is often cited as evidence that malaria vaccines can be developed, but is rarely used to guide the development. We are pursuing the development of vaccines based on antigens and immune responses...

  3. 76 FR 28819 - NUREG/CR-XXXX, Development of Quantitative Software Reliability Models for Digital Protection...

    Science.gov (United States)

    2011-05-18

    ... COMMISSION NUREG/CR-XXXX, Development of Quantitative Software Reliability Models for Digital Protection... issued for public comment a document entitled: NUREG/CR-XXXX, ``Development of Quantitative Software... development of regulatory guidance for using risk information related to digital systems in the...

  4. Opportunities and challenges for drug development: public-private partnerships, adaptive designs and big data

    Directory of Open Access Journals (Sweden)

    Oktay Yildirim

    2016-12-01

    Full Text Available Drug development faces the double challenge of increasing costs and increasing pressure on pricing. To avoid that lack of perceived commercial perspective will leave existing medical needs unmet, pharmaceutical companies and many other stakeholders are discussing ways to improve the efficiency of drug Research & Development. Based on an international symposium organized by the Medical School of the University of Duisburg-Essen (Germany and held in January 2016, we discuss the opportunities and challenges of three specific areas, i.e. public-private partnerships, adaptive designs and big data. Public-private partnerships come in many different forms with regard to scope, duration and type and number of participants. They range from project-specific collaborations to strategic alliances to large multi-party consortia. Each of them offers specific opportunities and faces distinct challenges. Among types of collaboration, investigator-initiated studies are becoming increasingly popular but have legal, ethical and financial implications. Adaptive trial designs are also increasingly discussed. However, adaptive should not be used as euphemism for the repurposing of a failed trial; rather it requires carefully planning and specification before a trial starts. Adaptive licensing can be a counter-part of adaptive trial design. The use of Big Data is another opportunity to leverage existing information into knowledge useable for drug discovery and development. Respecting limitations of informed consent and privacy is a key challenge in the use of Big Data. Speakers and participants at the symposium were convinced that appropriate use of the above new options may indeed help to increase the efficiency of future drug development.

  5. NETWORK GROUNDS OF DEVELOPMENT OF REGIONAL HEALTH PROTECTION

    Directory of Open Access Journals (Sweden)

    Yermolenko V. V.

    2015-09-01

    Full Text Available The article heads a series of the publications devoted to the solution of an actual problem of modern health care - a management problem at the regional level. The contradiction between expectations and needs of the population for high-quality medical services and quality of management of the medical organizations is shown in the Russian health system. This contradiction is shown at the micro and meso (regional level in poor quality of not medical part of medical services and in total generates a dissatisfaction of patients with quality of medical services in general. At this stage of reforming of health system in Russia, economic and administrative problems are main issues. It is necessary to master and quickly to introduce in work practice modern economic methods and administrative technologies for their decision. Network creation of the companies belongs to a remarkable trend of development modern societies and economics. The cluster campaign was widely adopted. Studying of network forms of the organizations is based on interdisciplinary researches on ecological, economic, administrative and relational approaches. Application of network structures in health sector is based on the new organizational and administrative principles, from which are main: principle of systems; principle of a synergy of material and immaterial resources; principle of trust; principle of reciprocity; principle of formation of network culture and ideological coordination of actors of a network; principle of economy of the valid human capital; accession of the network management and its actors to business services in relation to the diagnostic and treatment process; professionalizing of activity of infrastructure service of a network and its participants

  6. Technology development for evaluation of operational quantities in radiation protection

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jang Lyul; Chang, S. Y.; Lee, L. T.; Kim, B. H.; Chung, K. K.; Lee, J. I.; Lim, G. S.; Kim, J. S.; Nam, Y. M.; Chang, J. K.; Kim, D. Y.; Yang, J. S

    2000-03-01

    A study on the fabrication of a new personal thermo-luminescence dosimeter, which can evaluate the personal dose equivalent H{sub p}(d), has been performed. Optimum conditions for fabrication of a LiF:Mg,Cu,Na,Si TL phosphor powder has been determined and a disc type TL pellet has been fabricated from this TL powder. Another type of CaSO{sub 4}:Dy,Mo TL material has been also fabricated. These two TL materials have shown greater TL sensitivity than the foreign-made commercial TL materials. Mono-energetic fluorescence X-ray from 8.6 keV to 75 keV for use in performance testing of the developed TLDs energy response have been constructed and evaluated for the performance of the purity, air kerma, beam uniformity and distribution, and scattered fraction of X-rays. Reference neutron field of a D{sub 2}O moderated {sup 252}Cf source was characterized and the irradiation system using {sup 226}Ra and {sup 137}Cs sources was installed to construct the environmental gamma reference radiation and the low-level gamma radiation. A capability of calibration and measurement of KAERI In Vivo counting system for transuranic elements in the lung has been evaluated through the participation in the overseas intercomparison study on the In Vivo radioactivity measurement. An improvement and advancement of KAERI lung counting technology have been made by the analysis off uncertainties from the assumption of uniform radioactivity distribution in the lung, experimental determination and comparing of detection efficiency with different lung sets, and mathematical efficiency calibration of In Vivo counting system. (author)

  7. Confidentiality Protection of User Data and Adaptive Resource Allocation for Managing Multiple Workflow Performance in Service-Based Systems

    Science.gov (United States)

    An, Ho

    2012-01-01

    In this dissertation, two interrelated problems of service-based systems (SBS) are addressed: protecting users' data confidentiality from service providers, and managing performance of multiple workflows in SBS. Current SBSs pose serious limitations to protecting users' data confidentiality. Since users' sensitive data is sent in…

  8. Confidentiality Protection of User Data and Adaptive Resource Allocation for Managing Multiple Workflow Performance in Service-Based Systems

    Science.gov (United States)

    An, Ho

    2012-01-01

    In this dissertation, two interrelated problems of service-based systems (SBS) are addressed: protecting users' data confidentiality from service providers, and managing performance of multiple workflows in SBS. Current SBSs pose serious limitations to protecting users' data confidentiality. Since users' sensitive data is sent in…

  9. The park-view effect: Residential development is higher at the boundaries of protected areas.

    Science.gov (United States)

    Brambilla, Mattia; Ronchi, Silvia

    2016-11-01

    Land-use changes in the surrounding of protected areas might compromise their conservation efficacy, and thus the potential attractive effect that protected areas may exert on urban development is particularly concerning. We investigated whether the proximity to protected areas in a region (Lombardy, Italy) with a high density of urban areas and parks may increase the likelihood of residential development. The main change around protected areas was the loss of open areas (mostly due to development processes at the expense of arable land), which was higher in proximity of parks. Changes in residential discontinuous development were significantly and negatively related to proximity to parks, whereas changes in productive developments were unrelated to park proximity. The higher likelihood of residential development in proximity to parks is likely due to the attraction exerted by parks. The severe loss of open areas and increase of residential development around parks heavily impacted on habitat availability for a declining bird species (Alauda arvensis). Conservation policies considering also what happens around protected areas are urgently needed.

  10. Depression as an evolutionary adaptation: implications for the development of preclinical models.

    Science.gov (United States)

    Hendrie, C A; Pickles, A R

    2009-03-01

    Several authors have suggested that rather than being a disease state, depression is an evolutionary adaptation to human social organization. Adaptations are produced in response to selection pressures and similar adaptations may easily have evolved in a range of other species. The current paper seeks to identify the social pressures that may lead to a species developing depression as an adaptation and the potential benefits that this may confer. It also examines whether rats and mice, the species most commonly used to model depression in the laboratory, have social organizations in which selection pressures towards the development of depression as an adaptation are likely to exist. It is proposed that depression is a useful adaptation in group-living animals, where there is competition for a social rank that gives reproductive advantage over others. The cluster of symptoms associated with depression include altered activity patterns, reduced sociability and appetite, and increased submissiveness. This combination strongly suggests that the function of depression is to reduce the likelihood of an individual being subject to further attack once they have lost social status and so increase their chances of survival in the period immediately following this. Successful transition from high to low status may provide further opportunities to reproduce. Hence, animals that become depressed during this critical period gain a reproductive advantage over those that do not, as these are either killed or expelled from the group. Wild mice do not have social hierarchies and are highly territorial. Wild rats do have social hierarchies however these only compete for reproductive advantage at the level of the sperm, and social status does not translate into significantly greater access to mates. Therefore, there are no selection pressures in these species towards the development of depression and so it is most unlikely that rats and mice have this adaptation. It is concluded that

  11. Sustainable development through a gendered lens: climate change adaptation and disaster risk reduction.

    Science.gov (United States)

    Lewis, Nancy D

    2016-03-01

    The UN General Assembly has just adopted the post 2015 Sustainable Development Agenda articulated in the 17 Sustainable Development Goals (SDGs). Achieving the SDGs will be furthered by the closer integration of the climate change adaptation (CCA) and disaster risk reduction (DRR) agendas. Gender provides us a valuable portal for considering this integration. Acknowledging that gender relaters to both women and men and that men and women experience climate variability and disasters differently, in this paper the role of women in both CCA and DRR is explored, shifting the focus from women as vulnerable victims to women as critical agents for change with respect to climate change mitigation and adaptation and reduction of disaster risks. Appropriately targeted interventions can also empower women and contribute to more just and inclusive sustainable development.

  12. Adaptation for a Changing Environment: Developing learning and teaching with information and communication technologies

    Directory of Open Access Journals (Sweden)

    Adrian Kirkwood

    2006-09-01

    Full Text Available This article examines the relationship between the use of information and communication technologies (ICT and learning and teaching, particularly in distance education contexts. We argue that environmental changes (societal, educational, and technological make it necessary to adapt systems and practices that are no longer appropriate. The need to adapt, however, can be perceived as being technology-led and primarily concerned with requiring academic staff to develop their skills in using ICT. We provide a critique of continuing professional development (CPD for using ICT in teaching and learning that does not entail examining the impact of environmental changes upon the assumptions, goals, and strategies which underlie and shape an organisation’s educational practices. In particular, we oppose CPD that concentrates on the individual teacher and their use of ICT. Instead, we contend that professional development should focus upon the scholarship of teaching and learning, and must also reflect the wider organisational context within which ICT is managed and used.

  13. Factors Influencing Adaptive Marine Governance in a Developing Country Context: a Case Study of Southern Kenya

    Directory of Open Access Journals (Sweden)

    Louisa S. Evans

    2011-06-01

    Full Text Available Adaptive governance can be conceptualized as distinct phases of: 1 understanding environmental change; 2 using this understanding to inform decision making; and 3 acting on decisions in a manner that sustains resilience of desirable system states. Using this analytical framework, we explore governance in practice in two case studies in Kenya, that reflect the "messiness" of contemporary coastal governance in many developing country contexts. Findings suggest that adaptive marine governance is unlikely to be a smooth process of learning, knowledge sharing, and responding. There are institutional, sociocultural, and political factors, past and present, that influence each phase of both local and state decision making. New local institutions related to fisher associations and Beach Management Units influence learning and knowledge sharing in ways contrary to those expected of institutions that enable collaborative fisheries management. Similarly, state decision making is relatively uninformed by the diverse knowledge systems available in the coastal zone, despite the rhetoric of participation. Historical relations and modes of working continue to play a significant role in mediating the potential for adaptive governance in the future. The case studies are illustrative and point to a number of institutional and political issues that would need to be addressed in processes of governance reform towards more adaptive management in developing country contexts.

  14. Challenges and Opportunities for Mainstreaming Climate Change Adaptation into WaSH Development Planning in Ghana

    Science.gov (United States)

    2017-01-01

    Climate change threatens water, sanitation and hygiene (WaSH) facilities and services, as these are intimately linked to the water cycle and are vulnerable to changes in the quantity and quality of available water resources. Floods and droughts, which pollute and reduce water delivery respectively, have now become a perennial issue to deal with in the northern regions of Ghana. This study aimed to assess the degree to which climate change adaptation measures are mainstreamed into the water, sanitation and hygiene (WaSH) development planning process in Ghana. Stakeholders from government and non-government agencies were interviewed to gain perspectives on the threat of climate change, the inclusion of climate change in WaSH planning and the barriers preventing mainstreaming. Despite awareness of climate change, adaptation measures have not been considered, and the immediate WaSH needs remain the priority. Overall, stakeholders felt the adaptive capacity of the Municipality was low and that mainstreaming has not yet occurred. Despite the lack of progress, there are great opportunities for mainstreaming climate change adaptation into planning through increasing awareness and capacity, legislative and institutional changes and the development of participatory systems to provide early warning systems and disaster risk analyses that will inform future planning. PMID:28698518

  15. Adaptation of instruments developed to study the effectiveness of psychotherapeutic processes

    Directory of Open Access Journals (Sweden)

    Shushanikova, Anastasia A.

    2016-06-01

    Full Text Available The objective of the research was to adapt for use in Russian-language contexts a set of instruments that assess the effectiveness of psychotherapeutic practices. The instruments explore the effectiveness of different types of therapy, without evaluating the abstract, idealized characteristics or specifics of each approach, specialist, or therapeutic case. The adapted instruments are based on reflective data about the significance of therapeutic events, from the point of view of both the client and the therapist. We translated, edited, and adapted forms developed by John McLeod and Mick Cooper — a “Goals Form”, a “Goal Assessment Form”, a “Post-Session Form”, and a “Therapy Personalization Form”. The adaption was intended to cohere with the stylistic and cultural aspects of the Russian language. The research showed that the instruments and the methods have great potential for practical and theoretical application in qualitative studies to formulate hypotheses and to verify them in quantitative studies. The phenomenological analysis reveals the reliability, appropriateness, and validity of the adapted instruments for identifying specific meanings of the psychotherapeutic cases considered. The instruments can be used in studies exploring helpful aspects and effectiveness in different types of therapy (cognitive, existential, outdoor therapy, online counseling, etc. with different groups of clients. It is reasonable to continue the use of the Russian-language version of the instruments in further studies exploring the effectiveness of psychological practices. The adapted instruments facilitate comparison and cross-cultural studies, and formulation of meaningful hypotheses about the effectiveness and quality of the psychotherapeutic process.

  16. Development of orthogonally protected hypusine for solid-phase peptide synthesis.

    Science.gov (United States)

    Song, Aimin; Tom, Jeffrey; Yu, Zhiyong; Pham, Victoria; Tan, Dajin; Zhang, Dengxiong; Fang, Guoyong; Yu, Tao; Deshayes, Kurt

    2015-04-03

    An orthogonally protected hypusine reagent was developed for solid-phase synthesis of hypusinated peptides using the Fmoc/t-Bu protection strategy. The reagent was synthesized in an overall yield of 27% after seven steps from Cbz-Lys-OBzl and (R)-3-hydroxypyrrolidin-2-one. The side-chain protecting groups (Boc and t-Bu) are fully compatible with standard Fmoc chemistry and can be readily removed during the peptide cleavage step. The utility of the reagent was demonstrated by solid-phase synthesis of hypusinated peptides.

  17. Maternal regulation of offspring development in mammals is an ancient adaptation tied to lactation

    Directory of Open Access Journals (Sweden)

    Michael L. Power

    2013-12-01

    Full Text Available The developmental origins of health and disease (DOHaD is a paradigm for understanding metabolic diseases of modern humans. Vulnerability to disease is linked to perturbations in development during critical time periods in fetal and neonatal life. These perturbations are caused by environmental signals, often generated or transduced by the mother. The regulation of mammalian development depends to a large extent on maternal biochemical signals to her offspring. We argue that this adaptation is ancient, and originated with the evolution of lactation. Lactation evolved earlier than live birth and before the extensive placental development of modern eutherian mammals. Milk contains a host of signaling molecules including nutrients, immunoglobulins, growth factors and metabolic hormones. As evidenced by marsupials, lactation originally served to supply the biochemical factors for growth and development for what is essentially a fetus to a weanling transitioning to independent existence. In placental mammals maternal signaling in earliest life is accomplished through the maternal–placental–fetal connection, with more of development shifted to in utero life. However, significant development occurs postpartum, supported by milk. Mothers of all taxa provide biochemical signals to their offspring, but for non-mammalian mothers the time window is short. Developing mammals receive maternal biochemical signals over an extended period. These signals serve to guide normal development, but also can vary in response to environmental conditions. The ancient adaptation of lactation resulted in a lineage (mammals in which maternal regulation of offspring development evolved to a heightened degree, with the ability to modify development at multiple time points. Modern metabolic diseases may arise due to a mismatch between maternal regulation and eventual circumstances of the offspring, and due to a large proportion of mothers that exceed past evolutionary norms

  18. Adapting to Sea Level Rise and Storms: Missed Opportunities and Continuing Development (case studies from USA and Bulgaria)

    Science.gov (United States)

    Young, Robert; Stancheva, Margarita; Stanchev, Hristo; Palazov, Atanas; Peek, Katie; Coburn, Andrew; Griffith, Adam

    2014-05-01

    Over the last several years, there have been significant discussions within the global scientific and coastal zone management communities about the need to adapt to the realities of long-term sea level rise and to make coastal development more "resilient" to hazards and climate change. With all of the talk, publications, and recognition of the problem, you would think that we had made significant progress, but this is not the case. Once again, the USA has experienced the impact of a significant coastal storm, Hurricane Sandy. There were initially some serious post-Sandy discussions regarding the need to ensure that we simply don't "just put everything back were it was." Almost a year later, there have been few substantive moves to relocate property away from coastal hazards or to change the footprint of vulnerable coastal communities. This is particularly true of coastal resort communities in New York and New Jersey. Some communities have initiated large-scale efforts to elevate (in situ) infrastructure and private property. Raising buildings is only a workable solution if you also commit to holding all the beaches in place . . . forever. This is what the federal government has done for New Jersey and New York. The U. S. Army Corps of Engineers will be spending upward of US5 billion on shore protection projects following Hurricane Sandy. The vast majority of these funds will be spent pumping sand onto beaches from Delaware to Connecticut. The amount of sand they will move is staggering, approaching 25 to 35 million cubic meters. This is an adaptation model that cannot be exported to the rest of the USA. Nor can it be maintained for an extended period of time. Along the Black Sea Coast of Bulgaria the risk of storms is not as great as that of the US East Coast, but long-term sea level rise is still a threat. In Bulgaria, most coastal development problems occur simply because people continue to build in areas that are too close to the coast or in very high hazard

  19. Development of organic and hybrid glasses using Interpenetrating PolymerNetworks for artworks protection

    OpenAIRE

    2015-01-01

    This work position itself on a primary issue of heritage and more precisely on the preventive conservation of artworks. To provide a low cost solution to museums, capable of meeting the requirements set for the cultural heritage protection, we have developed new polymer glazing to protect works without altering their perception by the public. These materials will eventually be able to replace poly(methyl methacrylate) (PMMA) glazing, which are widely used but have high sensitivity to scratchi...

  20. How student models of expertise and innovation impact the development of adaptive expertise in medicine.

    Science.gov (United States)

    Mylopoulos, Maria; Regehr, Glenn

    2009-02-01

    The ability to innovate new solutions in response to daily workplace challenges is an important component of adaptive expertise. Exploring how to optimally develop this skill is therefore of paramount importance to education researchers. This is certainly no less true in health care, where optimal patient care is contingent on the continuous efforts of doctors and other health care workers to provide the best care to their patients through the development and incorporation of new knowledge. Medical education programmes must therefore foster the skills and attitudes necessary to engage future doctors in the systematic development of innovative problem solving. The aim of this paper is to describe the perceptions and experiences of medical students in their third and fourth years of training, and to explore their understanding of their development as adaptive experts. A sample of 25 medical students participated in individual 45-60-minute semi-structured interviews. Interviews were audiotaped, transcribed and entered into NVivo qualitative data analysis software to facilitate a thematic analysis. The analysis was both inductive, in that themes were generated from the data, and deductive, in that our data were meaningful when interpreted in the context of theories of adaptive expertise. Participants expressed a general belief that, as learners in the health care system, exerting any effort to be innovative was beyond the scope of their responsibilities. Generally, students suggested that innovative practice was the prerogative of experts and an outcome of expert development centred on the acquisition of knowledge and experience. Students' perceptions of themselves as having no responsibility to be innovative in their learning process have implications for their learning trajectories as adaptive experts.

  1. Scenario planning to leap-frog the Sustainable Development Goals: An adaptation pathways approach

    Directory of Open Access Journals (Sweden)

    J.R.A. Butler

    2016-01-01

    Full Text Available Few studies have examined how to mainstream future climate change uncertainty into decision-making for poverty alleviation in developing countries. With potentially drastic climate change emerging later this century, there is an imperative to develop planning tools which can enable vulnerable rural communities to proactively build adaptive capacity and ‘leap-frog’ the Sustainable Development Goals (SDGs. Using an example from Indonesia, we present a novel participatory approach to achieve this. We applied scenario planning to operationalise four adaptation pathways principles: (1 consideration of climate change as a component of multi-scale social-ecological systems; (2 recognition of stakeholders’ competing values, goals and knowledge through co-learning; (3 coordination of responses across multiple decision-making levels; and (4 identification of strategies which are ‘no regrets’, incremental (tackling proximate drivers of community vulnerability and transformative (tackling systemic drivers. Workshops with stakeholders from different administrative levels identified drivers of change, an aspirational vision and explorative scenarios for livelihoods in 2090, and utilised normative back-casting to design no regrets adaptation strategies needed to achieve the vision. The resulting ‘tapestry’ of strategies were predominantly incremental, and targeted conventional development needs. Few directly addressed current or possible future climate change impacts. A minority was transformative, and higher level stakeholders identified proportionately more transformative strategies than local level stakeholders. Whilst the vast majority of strategies were no regrets, some were potentially mal-adaptive, particularly for coastal areas and infrastructure. There were few examples of transformative innovations that could generate a step-change in linked human and environmental outcomes, hence leap-frogging the SDGs. We conclude that whilst

  2. OPPORTUNITIES FOR PSYCHO-MOTOR SKILLS DEVELOPMENT IN CHILDREN WITH DOWN SYNDROME - ADAPTED SWIMMING -

    Directory of Open Access Journals (Sweden)

    Chera-Ferrario B.

    2012-12-01

    Full Text Available Sport activities have a beneficial effect on the mind and body of any type of person. The benefits of sport are even more evident in children with Down Syndrome, who exhibit a general delay in neuro-motor structures. Our aim was to develop the psycho-motor skills in children with Down Syndrome through adapted swimming exercises. We believe that our involvement in adapted swimming for children with Down Syndrome may help develop certain aspects of psycho-motor abilities. The swimming took place with 6 Down Syndrome children from the Special Needs School in Targoviste, for a period of six months and the children being assisted by volunteer students from the Valahia University Department of Sport in Targoviste.The most important result was the children's delight in coming to the pool and taking part in the swimming lessons. Through the methods and exercises used and the devoted involvement of the volunteers, the children developed great levels of trust and courage and learned to swim using only aids. After performing motor skill tests on the children, we observed a general growth in the motor skills monitored.Continuation of the adapted swimming is very important in order to mobilize the skills obtained and continue development of psycho-motor abilities.

  3. Strategy of protected areas development in purposes of using and keeping bioresources and ecosystem services

    Directory of Open Access Journals (Sweden)

    Tatiana Vyacheslavovna Tikhonova

    2012-09-01

    Full Text Available Features and condition of existing system of especially protected natural territories of the Komi Republic are presented in this paper. Their specific environmental problems are defined. Strong sides and weaknesses of functioning and management of objects of special protection are provided. For approbation of a complex of methods of steady exploitation of this territory modeling objects of special protection are allocated and the economic assessment is carried out them. Potential recipients of benefits from use of bioresources and ecosystem services on modeling objects arerevealed. Theterritories possessing a reservefor increasein use of their resources and services are presented. Offers on strategy of development of a control system of especially protected natural territories of the Komi Republic are developed. Development strategy of control system ofespecially protected natural territories is consisting of someinstitutional decisions. This acceptance of federal-regional agreement about management control;creating of regional rules, which regulatethe usage of natural resources in especially protected natural territories; application of an integrated approach to the use of territories, which provide the bases to increase recreation and tourist industry; transfer buffer zone territories to biosphere reservation.

  4. Overview of current capabilities and research and technology developments for planetary protection

    Science.gov (United States)

    Frick, Andreas; Mogul, Rakesh; Stabekis, Pericles; Conley, Catharine A.; Ehrenfreund, Pascale

    2014-07-01

    The pace of scientific exploration of our solar system provides ever-increasing insights into potentially habitable environments, and associated concerns for their contamination by Earth organisms. Biological and organic-chemical contamination has been extensively considered by the COSPAR Panel on Planetary Protection (PPP) and has resulted in the internationally recognized regulations to which spacefaring nations adhere, and which have been in place for 40 years. The only successful Mars lander missions with system-level “sterilization” were the Viking landers in the 1970s. Since then different cleanliness requirements have been applied to spacecraft based on their destination, mission type, and scientific objectives. The Planetary Protection Subcommittee of the NASA Advisory Council has noted that a strategic Research & Technology Development (R&TD) roadmap would be very beneficial to encourage the timely availability of effective tools and methodologies to implement planetary protection requirements. New research avenues in planetary protection for ambitious future exploration missions can best be served by developing an over-arching program that integrates capability-driven developments with mission-driven implementation efforts. This paper analyzes the current status concerning microbial reduction and cleaning methods, recontamination control and bio-barriers, operational analysis methods, and addresses concepts for human exploration. Crosscutting research and support activities are discussed and a rationale for a Strategic Planetary Protection R&TD Roadmap is outlined. Such a roadmap for planetary protection provides a forum for strategic planning and will help to enable the next phases of solar system exploration.

  5. Local Landscape Protection and Development%乡土景观的保护与发展

    Institute of Scientific and Technical Information of China (English)

    郭亮

    2009-01-01

    近年来,随着古建筑的发展与保护的提出,乡土景观的保护与发展也迅速蓬勃发展. 文章论述了对乡土景观的概念、自已的认识和理解及设计理念.%Along with historic building development and protection statement, local landscape protection and development also rapid vigorous development, this paper elaborated the local landscape concept, own understanding and understanding and design idea.

  6. Social Influences on the Development of Children's Adaptive Help Seeking: The Role of Parents, Teachers, and Peers.

    Science.gov (United States)

    Newman, Richard S.

    2000-01-01

    Maintains that adaptive help seeking exemplifies how elementary- and middle-school students regulate their own learning and intellectual development. Discusses how parents, teachers, and peers contribute to the development of children's skills and attitudes associated with adaptive help seeking. Traces early help-seeking behaviors in the home and…

  7. Development of an Adaptive Learning System with Multiple Perspectives based on Students' Learning Styles and Cognitive Styles

    Science.gov (United States)

    Yang, Tzu-Chi; Hwang, Gwo-Jen; Yang, Stephen Jen-Hwa

    2013-01-01

    In this study, an adaptive learning system is developed by taking multiple dimensions of personalized features into account. A personalized presentation module is proposed for developing adaptive learning systems based on the field dependent/independent cognitive style model and the eight dimensions of Felder-Silverman's learning style. An…

  8. Development of an item bank for computerized adaptive test (CAT) measurement of pain

    DEFF Research Database (Denmark)

    Petersen, Morten Aa.; Aaronson, Neil K; Chie, Wei-Chu

    2016-01-01

    PURPOSE: Patient-reported outcomes should ideally be adapted to the individual patient while maintaining comparability of scores across patients. This is achievable using computerized adaptive testing (CAT). The aim here was to develop an item bank for CAT measurement of the pain domain as measured...... by the EORTC QLQ-C30 questionnaire. METHODS: The development process consisted of four steps: (1) literature search, (2) formulation of new items and expert evaluations, (3) pretesting and (4) field-testing and psychometric analyses for the final selection of items. RESULTS: In step 1, we identified 337 pain...... were obtained from 1103 cancer patients from five countries. Psychometric evaluations showed that 16 items could be retained in a unidimensional item bank. Evaluations indicated that use of the CAT measure may reduce sample size requirements with 15-25 % compared to using the QLQ-C30 pain scale...

  9. Vocal learning beyond imitation: mechanisms of adaptive vocal development in songbirds and human infants.

    Science.gov (United States)

    Tchernichovski, Ofer; Marcus, Gary

    2014-10-01

    Studies of vocal learning in songbirds typically focus on the acquisition of sensory templates for song imitation and on the consequent process of matching song production to templates. However, functional vocal development also requires the capacity to adaptively diverge from sensory templates, and to flexibly assemble vocal units. Examples of adaptive divergence include the corrective imitation of abnormal songs, and the decreased tendency to copy over-abundant syllables. Such frequency-dependent effects might mirror tradeoffs between the assimilation of group identity (culture) while establishing individual and flexibly expressive songs. Intriguingly, although the requirements for vocal plasticity vary across songbirds, and more so between birdsong and language, the capacity to flexibly assemble vocal sounds develops in a similar, stepwise manner across species. Therefore, universal features of vocal learning go well beyond the capacity to imitate. Copyright © 2014 Elsevier Ltd. All rights reserved.

  10. Developing an effective adaptive monitoring network to support integrated coastal management in a multiuser nature reserve

    Directory of Open Access Journals (Sweden)

    Pim Vugteveen

    2015-03-01

    Full Text Available We elaborate the necessary conceptual and strategic elements for developing an effective adaptive monitoring network to support Integrated Coastal Management (ICM in a multiuser nature reserve in the Dutch Wadden Sea Region. We discuss quality criteria and enabling actions essential to accomplish and sustain monitoring excellence to support ICM. The Wadden Sea Long-Term Ecosystem Research project (WaLTER was initiated to develop an adaptive monitoring network and online data portal to better understand and support ICM in the Dutch Wadden Sea Region. Our comprehensive approach integrates ecological and socioeconomic data and links research-driven and policy-driven monitoring for system analysis using indicators of pressures, state, benefits, and responses. The approach and concepts we elaborated are transferable to other coastal regions to accomplish ICM in complex social-ecological systems in which scientists, multisectoral stakeholders, resource managers, and governmental representatives seek to balance long-term ecological, economic, and social objectives within natural limits.

  11. Energy consumption in development countries - effects on economics and compulsory adaptation of oil importers and consumers

    Energy Technology Data Exchange (ETDEWEB)

    Czakainski, M.

    1983-09-01

    Energy supply of developing countries is mainly based on mineral oil products and traditional energy carriers. The oil-importing developing countries were hard hit in their development efforts by the two oil-price surges of 1973/74 and, especially, of 1979/80. Any adaptation measures taken by the oil-importing countries of the third world should aim at tapping their own energy reserves, at a mature energy policy concerning concepts and instruments and at restructuring the strong dependence on oil of their consumption structures.

  12. Development and evaluation of a method of calibrating medical displays based on fixed adaptation

    Energy Technology Data Exchange (ETDEWEB)

    Sund, Patrik, E-mail: patrik.sund@vgregion.se; Månsson, Lars Gunnar; Båth, Magnus [Department of Medical Physics and Biomedical Engineering, Sahlgrenska University Hospital, Gothenburg SE-41345, Sweden and Department of Radiation Physics, University of Gothenburg, Gothenburg SE-41345 (Sweden)

    2015-04-15

    Purpose: The purpose of this work was to develop and evaluate a new method for calibration of medical displays that includes the effect of fixed adaptation and by using equipment and luminance levels typical for a modern radiology department. Methods: Low contrast sinusoidal test patterns were derived at nine luminance levels from 2 to 600 cd/m{sup 2} and used in a two alternative forced choice observer study, where the adaptation level was fixed at the logarithmic average of 35 cd/m{sup 2}. The contrast sensitivity at each luminance level was derived by establishing a linear relationship between the ten pattern contrast levels used at every luminance level and a detectability index (d′) calculated from the fraction of correct responses. A Gaussian function was fitted to the data and normalized to the adaptation level. The corresponding equation was used in a display calibration method that included the grayscale standard display function (GSDF) but compensated for fixed adaptation. In the evaluation study, the contrast of circular objects with a fixed pixel contrast was displayed using both calibration methods and was rated on a five-grade scale. Results were calculated using a visual grading characteristics method. Error estimations in both observer studies were derived using a bootstrap method. Results: The contrast sensitivities for the darkest and brightest patterns compared to the contrast sensitivity at the adaptation luminance were 37% and 56%, respectively. The obtained Gaussian fit corresponded well with similar studies. The evaluation study showed a higher degree of equally distributed contrast throughout the luminance range with the calibration method compensated for fixed adaptation than for the GSDF. The two lowest scores for the GSDF were obtained for the darkest and brightest patterns. These scores were significantly lower than the lowest score obtained for the compensated GSDF. For the GSDF, the scores for all luminance levels were statistically

  13. Parenting behaviours associated with the development of adaptive and maladaptive offspring personality traits.

    Science.gov (United States)

    Johnson, Jeffrey G; Liu, Lydia; Cohen, Patricia

    2011-08-01

    To investigate the associations of beneficial parenting behaviours with adaptive and maladaptive offspring personality traits that persist into adulthood among individuals in the community. Families (n = 669) participating in the Children in the Community Study were interviewed during the childhood, adolescence, emerging adulthood, and adulthood of the offspring at the mean ages of 6, 14, 16, 22, and 33 years. Twelve types of beneficial maternal and paternal child-rearing behaviour, reported by offspring at the mean age of 16 years, were associated with elevated offspring personality resiliency, at the mean ages of 22 and 33 years, and with low offspring personality disorder trait levels. These longitudinal associations remained significant when histories of childhood behaviour problems and parental psychiatric disorder were controlled statistically. Similar linear (that is, dose-dependent) associations were observed between the number of beneficial parenting behaviours during childhood and adaptive and maladaptive offspring traits at the mean ages of 22 and 33 years. Maternal and paternal behaviours were independently associated with both adaptive and maladaptive offspring traits. Beneficial maternal and paternal child-rearing behaviours may promote the development of adaptive offspring personality traits that endure into adulthood, and they may be prospectively associated with reduced levels of maladaptive offspring traits. These associations may not be attributable to childhood behaviour problems or parental psychiatric disorders, and they may be equally evident during early and middle adulthood.

  14. Development of Ultraviolet (UV) Radiation Protective Fabric Using Combined Electrospinning and Electrospraying Technique

    Science.gov (United States)

    Sinha, Mukesh Kumar; Das, B. R.; Kumar, Kamal; Kishore, Brij; Prasad, N. Eswara

    2017-03-01

    The article reports a novel technique for functionization of nanoweb to develop ultraviolet (UV) radiation protective fabric. UV radiation protection effect is produced by combination of electrospinning and electrospraying technique. A nanofibrous web of polyvinylidene difluoride (PVDF) coated on polypropylene nonwoven fabric is produced by latest nanospider technology. Subsequently, web is functionalized by titanium dioxide (TiO2). The developed web is characterized for evaluation of surface morphology and other functional properties; mechanical, chemical, crystalline and thermal. An optimal (judicious) nanofibre spinning condition is achieved and established. The produced web is uniformly coated by defect free functional nanofibres in a continuous form of useable textile structural membrane for ultraviolet (UV) protective clothing. This research initiative succeeds in preparation and optimization of various nanowebs for UV protection. Field Emission Scanning Electron Microscope (FESEM) result reveals that PVDF webs photo-degradative behavior is non-accelerated, as compared to normal polymeric grade fibres. Functionalization with TiO2 has enhanced the photo-stability of webs. The ultraviolet protection factor of functionalized and non-functionalized nanowebs empirically evaluated to be 65 and 24 respectively. The developed coated layer could be exploited for developing various defence, para-military and civilian UV protective light weight clothing (tent, covers and shelter segments, combat suit, snow bound camouflaging nets). This research therefore, is conducted in an attempt to develop a scientific understanding of PVDF fibre coated webs for photo-degradation and applications for defence protective textiles. This technological research in laboratory scale could be translated into bulk productionization.

  15. Evolution of the radiological protection policy. Applications in developing countries. IPEN a case of study

    Energy Technology Data Exchange (ETDEWEB)

    Gordon, A.M.P.L.; Sordi, G.M.A. A. [Instituto de Pesquisas Energeticas e Nucleares - IPEN, Sao Paulo (Brazil)

    2006-07-01

    This paper aims to show the radiological protection development in Brazil from the beginning, when President Joao Cafe Filho signed an agreement with the U.S.A. In this agreement, Brazil joined the 'Atoms for Peace' program established on August 3., 1955. Yet in 1955, Brazil participated as a foundation member in the International Atomic Energy Agency (IAEA). As a result, the Iea - 'Instituto de Energia Atomica'- was created on August 31., 1956 and a research reactor type swimming pool was installed to produce radioisotopes and prepare experts in the field of nuclear activities. This reactor is maintained in operation at the Instituto de Pesquisas Energeticas e Nucleares (IPEN), former Iea. Having the Iea as a case of study, we analyze the radiological protection evolution during the fifty years of its life. We correlate this development with the Brazilian National Nuclear Energy Commission (CNEN) Regulations. CNEN was also created in 1956. The first safety standard in Brazil was delivered in 1973. Therefore, this paper will focus the radiological protection development at national level. Both institutions followed the international radiological protection recommendations, under the difficulties imposed by the historical conditions of a developing country. In order to have an outline of the radiological protection development, we inform that it was started as a section of the Radiological Division at the Iea. At that time, the Iea had four divisions. The radiological protection was performed by four people, being two physicists and two technicians that accomplished all the duties. On that occasion, approximately 30 people operated the Iea. The work staff at IPEN increased, arriving to 1600 people in 1998, including 150 persons in the radiological protection activities. Nowadays, 1200 people, including 100 persons in the health physics duties operate the IPEN. (authors)

  16. Development of Ultraviolet (UV) Radiation Protective Fabric Using Combined Electrospinning and Electrospraying Technique

    Science.gov (United States)

    Sinha, Mukesh Kumar; Das, B. R.; Kumar, Kamal; Kishore, Brij; Prasad, N. Eswara

    2017-06-01

    The article reports a novel technique for functionization of nanoweb to develop ultraviolet (UV) radiation protective fabric. UV radiation protection effect is produced by combination of electrospinning and electrospraying technique. A nanofibrous web of polyvinylidene difluoride (PVDF) coated on polypropylene nonwoven fabric is produced by latest nanospider technology. Subsequently, web is functionalized by titanium dioxide (TiO2). The developed web is characterized for evaluation of surface morphology and other functional properties; mechanical, chemical, crystalline and thermal. An optimal (judicious) nanofibre spinning condition is achieved and established. The produced web is uniformly coated by defect free functional nanofibres in a continuous form of useable textile structural membrane for ultraviolet (UV) protective clothing. This research initiative succeeds in preparation and optimization of various nanowebs for UV protection. Field Emission Scanning Electron Microscope (FESEM) result reveals that PVDF webs photo-degradative behavior is non-accelerated, as compared to normal polymeric grade fibres. Functionalization with TiO2 has enhanced the photo-stability of webs. The ultraviolet protection factor of functionalized and non-functionalized nanowebs empirically evaluated to be 65 and 24 respectively. The developed coated layer could be exploited for developing various defence, para-military and civilian UV protective light weight clothing (tent, covers and shelter segments, combat suit, snow bound camouflaging nets). This research therefore, is conducted in an attempt to develop a scientific understanding of PVDF fibre coated webs for photo-degradation and applications for defence protective textiles. This technological research in laboratory scale could be translated into bulk productionization.

  17. Career and Talent Development Self-Efficacy Scale: Adaptation and Validation in the Turkish Population

    OpenAIRE

    Mehmet Emin Turan; Eyüp Çelikl; Murat İskender

    2015-01-01

    The aim of the study is to adapt and conduct reliability and validity studies of the Career and Talent Development Self-Efficacy Scale. Participants were 1047 students in İstanbul. To assess content validity, expert consultancy was utilized and to assess construct validity confirmatory factor analysis was utilized. Reliability of the scale was examined with Cronbach’s Alpha, split-half reliability, test of upper and lower 27% of the groups in terms of item mean differences. Confirmatory facto...

  18. Developing and Evaluating an Adaptive Business English Self-Learning System for EFL Vocabulary Learning

    OpenAIRE

    Yen-Hui Wang

    2014-01-01

    This paper developed an adaptive Business English self-learning system for EFL vocabulary learning. The components of word reoccurrence and learner engagement have been built into the system where the amount of unknown word reexposure in various customized texts increases and vocabulary enhancement tasks are added to promote learner engagement with wanted words. To evaluate the system effectiveness on EFL vocabulary learning, the experimental group read system-screened texts with immediate an...

  19. Development of adaptive core emulator for PMS-XRBP of CE type plant

    Energy Technology Data Exchange (ETDEWEB)

    Song, Jae Seung; Zee, Sung Quun; Lee, Chung Chan; Lee, Ki Bog; Rhy, Hyo Sang; Chang, Jong Hwa; Lee, Young Ouk; Baek, Seung Min; Seo, Ho Joon

    1996-12-01

    The purpose of this report is to develop ONED-based adaptive core emulator (ACE) for Korean Standard Nuclear Power Plant. This report is first year report and includes (1) augmentation of ONED94 I/O system (2) non-equilibrium xenon initialization for core transient simulation (3) ONED94 verification via plant measurements (4) automatic data link system from PMS and personal computer. (author). 4 tabs., 4 figs., 8 refs.

  20. Modular autopilot design and development featuring Bayesian non-parametric adaptive control

    Science.gov (United States)

    Stockton, Jacob

    Over the last few decades, Unmanned Aircraft Systems, or UAS, have become a critical part of the defense of our nation and the growth of the aerospace sector. UAS have a great potential for the agricultural industry, first response, and ecological monitoring. However, the wide range of applications require many mission-specific vehicle platforms. These platforms must operate reliably in a range of environments, and in presence of significant uncertainties. The accepted practice for enabling autonomously flying UAS today relies on extensive manual tuning of the UAS autopilot parameters, or time consuming approximate modeling of the dynamics of the UAS. These methods may lead to overly conservative controllers or excessive development times. A comprehensive approach to the development of an adaptive, airframe-independent controller is presented. The control algorithm leverages a nonparametric, Bayesian approach to adaptation, and is used as a cornerstone for the development of a new modular autopilot. Promising simulation results are presented for the adaptive controller, as well as, flight test results for the modular autopilot.

  1. Possibilities for the development of ecotourism in protected areas of Western Serbia

    Directory of Open Access Journals (Sweden)

    Miljković Olgica

    2012-01-01

    Full Text Available Sustainable tourism is an important element of modern tourism, which are strictly controlled by the impact of tourism on the environment. Balanced ecological, economic and sociocultural components of tourism are therefore more frequently mentioned in the programs and strategies of tourism development. Sustainable tourism is particularly applicable to the development of tourism in the category of protected natural areas. These natural systems (national parks, nature parks, nature reserves and natural monuments are all interesting areas for various segments of the tourist. Typically, this is ecotourism - a modern form of tourism in which through education, volunteering, learning about nature, we help protect and preserve nature. Tourism development in protected natural areas is particularly sensitive, and as such it involves the determination of carrying capacity, limits of acceptable changes, environmental impact assessment, tourism zoning and designing codes of ethics that would help tourists to coordinate their activities with the values of the environment. [Projekat Ministarstva nauke Republike Srbije, br. 176008

  2. Development of Uncertainty Analysis Method for SMART Digital Core Protection and Monitoring System

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Bon Seung; In, Wang Kee; Hwang, Dae Hyun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-05-15

    The Korea Atomic Energy Research Institute has developed a system-integrated modular advanced reactor (SMART) for a seawater desalination and electricity generation. Online digital core protection and monitoring systems, called SCOPS and SCOMS respectively were developed. SCOPS calculates minimum DNBR and maximum LPD based on the several online measured system parameters. SCOMS calculates the variables of limiting conditions for operation. KAERI developed overall uncertainty analysis methodology which is used statistically combining uncertainty components of SMART core protection and monitoring system. By applying overall uncertainty factors in on-line SCOPS/SCOMS calculation, calculated LPD and DNBR are conservative with a 95/95 probability/confidence level. In this paper, uncertainty analysis method is described for SMART core protection and monitoring system

  3. Public Goods, Environmental Protection,and the Development Paradigm in Rural China

    Institute of Scientific and Technical Information of China (English)

    LiZhou

    2004-01-01

    Ecological environment protection will and should not stop as regional public goods;instead, it has been gradually regarded as global public goods. That is why the responsibility of environment protection belongs to public institutions: government organizations (GO) and non-government organizations (NGO). The ecological environment protection problems in China's rural areas stem from the absence of government responsibilities with regard to consensuses on issues of rural public goods that are basically sourced from two superstitions on the government's development paradigm: one is attaching too much importance on economic growth; the other is relying entirely on market resource-allocation capacity. These two superstitions of China "s government obviously lead to the shortage of public goods in rural areas. It is necessary that GO's and NGO's clearly define their specific responsibilities, reflect on the development paradigm; establish a more scientific development model and take concrete actions based on it.

  4. Sexually dimorphic adaptations in basal maternal stress physiology during pregnancy and implications for fetal development.

    Science.gov (United States)

    Giesbrecht, Gerald F; Campbell, Tavis; Letourneau, Nicole

    2015-06-01

    There is clear evidence of reciprocal exchange of information between the mother and fetus during pregnancy but the majority of research in this area has focussed on the fetus as a recipient of signals from the mother. Specifically, physiological signals produced by the maternal stress systems in response to the environment may carry valuable information about the state of the external world. Prenatal stress produces sex-specific adaptations within fetal physiology that have pervasive and long-lasting effects on development. Little is known, however, about the effects of sex-specific fetal signals on maternal adaptations to pregnancy. The current prospective study examined sexually dimorphic adaptations within maternal stress physiology, including the hypothalamic-adrenal-pituitary (HPA) axis and the autonomic nervous system (ANS) and associations with fetal growth. Using diurnal suites of saliva collected in early and late pregnancy, we demonstrate that basal cortisol and salivary alpha-amylase (sAA) differ by fetal sex. Women carrying female fetuses displayed greater autonomic arousal and flatter (but more elevated) diurnal cortisol patterns compared to women carrying males. Women with flatter daytime cortisol trajectories and more blunted sAA awakening responses also had infants with lower birth weight. These maternal adaptations are consistent with sexually dimorphic fetal developmental/evolutionary adaptation strategies that favor growth for males and conservation of resources for females. The findings provide new evidence to suggest that the fetus contributes to maternal HPA axis and ANS regulation during pregnancy and that these systems also contribute to the regulation of fetal growth. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. The protection and development of historic Lougang water resource features along Lake Tai

    Science.gov (United States)

    Deng, J.; Tan, X. M.; Li, Y. P.; Wan, J. H.; Liu, J. G.; Zhou, B.

    2016-08-01

    Overcoming the conflicts between protecting water resource heritage features and the sustainable development of modern society is a major undertaking. Lougangs (rivulets) and polders are Lake-Tai-Basin-specific water resource engineering projects that hold a significant historic position. This paper presents background on water resource heritage features, based on the origins and evolution of Lougangs along Lake Tai. Through analysis of their value and current standing, we propose countermeasures for protection and development of the Lougang water resource heritage features along Lake Tai.

  6. Developing integrated approaches to climate change adaptation in rural communities of the Peruvian Andes

    Science.gov (United States)

    Huggel, Christian

    2010-05-01

    Over centuries, Andean communities have developed strategies to cope with climate variability and extremes, such as cold waves or droughts, which can have severe impacts on their welfare. Nevertheless, the rural population, living at altitudes of 3000 to 4000 m asl or even higher, remains highly vulnerable to external stresses, partly because of the extreme living conditions, partly as a consequence of high poverty. Moreover, recent studies indicate that climatic extreme events have increased in frequency in the past years. A Peruvian-Swiss Climate Change Adaptation Programme in Peru (PACC) is currently undertaking strong efforts to understand the links between climatic conditions and local livelihood assets. The goal is to propose viable strategies for adaptation in collaboration with the local population and governments. The program considers three main areas of action, i.e. (i) water resource management; (ii) disaster risk reduction; and (iii) food security. The scientific studies carried out within the programme follow a highly transdisciplinary approach, spanning the whole range from natural and social sciences. Moreover, the scientific Peruvian-Swiss collaboration is closely connected to people and institutions operating at the implementation and political level. In this contribution we report on first results of thematic studies, address critical questions, and outline the potential of integrative research for climate change adaptation in mountain regions in the context of a developing country.

  7. Collaborative Software Development in Support of Fast Adaptive AeroSpace Tools (FAAST)

    Science.gov (United States)

    Kleb, William L.; Nielsen, Eric J.; Gnoffo, Peter A.; Park, Michael A.; Wood, William A.

    2003-01-01

    A collaborative software development approach is described. The software product is an adaptation of proven computational capabilities combined with new capabilities to form the Agency's next generation aerothermodynamic and aerodynamic analysis and design tools. To efficiently produce a cohesive, robust, and extensible software suite, the approach uses agile software development techniques; specifically, project retrospectives, the Scrum status meeting format, and a subset of Extreme Programming's coding practices are employed. Examples are provided which demonstrate the substantial benefits derived from employing these practices. Also included is a discussion of issues encountered when porting legacy Fortran 77 code to Fortran 95 and a Fortran 95 coding standard.

  8. Cytolethal distending toxin as virulence factor, protective antigen, and target for vaccine development

    Directory of Open Access Journals (Sweden)

    Lagergård T

    2012-12-01

    Full Text Available Teresa Lagergård,1 Jerry Keith21Institute of Biomedicine, Department of Microbiology and Immunology, Sahlgrenska Academy, University of Gothenburg, Göteborg, Sweden; 2Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD, NIH, Bethesda, MD, USAAbstract: This review explores the cytolethal distending toxin (CDT as a virulence factor, protective antigen, and a vaccine candidate in diseases caused by the following bacterial pathogens: Haemophilus ducreyi (HdCDT, Aggregatibacter actinomycetemcomitans, Campylobacter jejuni, and Helicobacter hepaticus. The review highlights some of the important evidence indicating that CDT is not only a commonly invoked virulence factor involved in pathogenesis of infection caused by these bacteria, but is also a protective antigen, such that specific antibodies will neutralize cell damage caused by the toxin. This justifies the development of toxoids as vaccine candidates. The first immunogenic toxoid was produced by formaldehyde treatment of HdCDT and has been used to study the involvement of antibodies in protection against infection and its use as a future vaccine component. The development of such toxoid vaccines may facilitate the studies of protection and immunoprophylaxis in diseases caused by CDT-producing bacteria.Keywords: cytolethal distending toxin, virulence factor, protective antigen, Haemophilus ducreyi, Aggregatibacter actinomycetemcomitans, Campylobacter jejuni, toxoid vaccine

  9. CAPACITY BUILDING FOR CLIMATE CHANGE ADAPTATION: MODULES FOR AGRICULTURAL EXTENSION CURRICULUM DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    B.O. Ogunbameru

    2013-02-01

    Full Text Available Basically, climate change refers to any change in climate overtime, generally caused by natural variability and/or human activities. It has great devastating impact, particularly on agriculture and by extrapolation on farmers and the national economy. The frontline agricultural extension workers are expected to be among the principal stakeholders to teach farmers how to cope with climate change. Consequently, there is a need to develop appropriate teaching package for the training of the frontline agricultural extension workers, based on the myriad of adaptation strategies and practices available in the literature. This paper synthesizes the rationale for capacity building in climate change and the adaptation or coping strategies. The modules (train-the-trainer for teaching agricultural extension workers and farmers are documented in the paper.

  10. Early and late rate of force development: differential adaptive responses to resistance training?

    DEFF Research Database (Denmark)

    Andersen, L L; Andersen, Jesper Løvind; Zebis, M K

    2010-01-01

    The objective of this study is to investigate the potentially opposing influence of qualitative and quantitative muscular adaptations in response to high-intensity resistance training on contractile rate of force development (RFD) in the early (200 ms) of rising muscle force. Fifteen healthy young...... the vastus lateralis. The main findings were that RFD in the late phase of rising muscle force increased in response to resistance training whereas early RFD remained unchanged and early relative RFD (i.e., RFD/MVC) decreased. Quantitatively, muscle fiber cross-sectional area and MVC increased whereas......-intensity resistance training due to differential influences of qualitative and quantitative muscular adaptations on early and later phases of rising muscle force....

  11. Development of a Programming Adapter for a Classified-Data Processor Device

    Energy Technology Data Exchange (ETDEWEB)

    PEREA,DOMINIC A.

    2000-08-09

    This summer, the author was tasked with the development of a design and prototype for a Programming Adapter (PA). This device must interface to a specialized cluster of computers at a US Air Force programming station. The PA is a command/response system capable of recognizing commands from a host Programming Computer (PC) generating a response to these commands according to design requirements. The PA must also route classified serial data between a programming station and any target devices on the PA without compromising the data. In this manner, classified data can pass through the adapter, but when data transfer is complete, the PA can be handled as an unclassified piece of hardware.

  12. Successful cross-protective efficacy induced by heat-adapted live attenuated nephropathogenic infectious bronchitis virus derived from a natural recombinant strain.

    Science.gov (United States)

    Lim, Tae-Hyun; Youn, Ha-Na; Yuk, Seong-Su; Kwon, Jung-Hoon; Hong, Woo-Tack; Gwon, Gyeong-Bin; Lee, Jung-Ah; Lee, Joong-Bok; Lee, Sang-Won; Song, Chang-Seon

    2015-12-16

    A natural recombinant nephropathogenic K40/09 strain of infectious bronchitis virus (IBV) was heat-adapted for possible future use as live attenuated vaccine. The K40/09 strain was selected during successive serial passages in specific-pathogen free (SPF) embryonated eggs at sub-optimal higher temperature (56°C). Unlike the parental strain, the attenuated strain, designated K40/09 HP50, was found to be safe in 1-day-old SPF chicks, which showed neither mortality nor signs of morbidity, and rarely induced ciliostasis or histological changes in the trachea and kidney after intraocular and fine-spray administration. K40/09 HP50 provided almost complete protection against two distinct subgroups of a nephropathogenic strain (KM91-like and QX-like subgroup) and elicited the production of high titers of neutralizing antibody (neutralization index of 3.6). We conclude that the K40/09 HP50 vaccine virus is rapidly attenuated by heat adaptation and exhibits the desired level of attenuation, immunogenicity, and protective efficacy required for a live attenuated vaccine. These results indicate that the K40/09 vaccine could be helpful for the reduction of economic losses caused by recently emergent nephropathogenic IBV infection in many countries.

  13. The Theory of Political Tariff Protection for Agricultural Sector in Developing Countries

    Directory of Open Access Journals (Sweden)

    Yaser Feizabadi

    2014-03-01

    Full Text Available This paper aims to analyze tariff protection policies in the agricultural sector of developing countries. The agricultural tariff structure in developing countries is characterized by: i high average tariffs, ii the existence of tariff escalation, iii dispersion of nominal tariffs across tariff lines, and iv a wide gap between average nominal tariffs and import-weighted average tariffs. Consequently, some features can be extracted that are consistent with the observed patterns of tariff protection in developing countries: i escalation of nominal tariff rates with the degree of processing, ii higher average tariffs in the agricultural sector compared to agriculture in developed countries, and iii higher non-agricultural than agricultural tariff protection. Here the Theory of Political Tariff Protection for Agricultural Sector in developing countries is described. This theory allows us to identify two sets of products. Agricultural products for which tariffs are higher than their political fitted values, therefore, tariff cuts should occur in a long period of time and for which tariffs are higher than their political fitted values therefore tariff reductions would not be politically costly.

  14. Development Interventions and Agriculture Adaptation: A Social Network Analysis of Farmer Knowledge Transfer in Ghana

    Directory of Open Access Journals (Sweden)

    Kirstie Cadger

    2016-07-01

    Full Text Available Social ties play an important role in agricultural knowledge exchange, particularly in developing countries with high exposure to agriculture development interventions. Institutions often facilitate agricultural training projects, with a focus on agroecological practices, such as agroforestry and agrobiodiversity. The structural characteristics of social networks amongst land managers influences decision-making to adopt such adaptive agroecoloigcal practice; however, the extent of knowledge transfer beyond direct project participants is often unknown. Using a social network approach, we chart the structure of agrarian knowledge networks (n = 131 in six communities, which have been differentially exposed to agriculture development interventions in Ghana. Farmer network size, density and composition were distinctly variable; development project-affiliated farmers were embedded in larger networks, had non-affiliated farmers within their networks, were engaged in more diverse agricultural production and reported adopting and adapting agroecological practice more frequently. Such bridging ties that link across distinctive groups in a network can expose network members to new and innovative agroecological practices, such as increasing agrobiodiversity, thus, contributing to livelihood strategies that mitigate environmental and market risk. Furthermore, we show that these knowledge networks were crop-specific where network size varied given the type of crop produced. Such factors, which may influence the rate and extent of agroecological knowledge diffusion, are critical for the effectiveness of land management practices as well as the persistence of agriculture development interventions.

  15. [Protection, exploitation and utilization states of specialized Mongolian folk medicine resources and related development strategy].

    Science.gov (United States)

    Zhang, Chun-hong; Man, Da; Wu, Guo-dong; Li, Zhen-hua; Zhao, Dong-dong; Liu, Yong; Li, Min-hui

    2015-03-01

    Mongolian folk medicine resource is the origin of Mongolian medicine development, even more important of which is the specialized Mongolian folk medicine resources with regional and high medicine quality, it processes distinctive national characteristics with irreplaceable important position in traditional Mongolian medicine. Nevertheless, due to the serious destroy of ecological environment and sharp increase of demands, etc. A lot of specialized Mongolian folk medicine resources were endangered, and there still existed some problems in the protection and exploitation and utilization. This paper intends to provide comprehensive insight into the species protection and exploitation and utilization states of specialized Mongolian folk medicine resources. The application and protection status and the existing problems were reviewed, and the development strategies of Mongolian folk medicine resource were analyzed.

  16. Stakeholder and expert-guided scenarios for agriculture and landscape development in a groundwater protection area

    DEFF Research Database (Denmark)

    Vejre, Henrik; Vesterager, Jens Peter; Kristensen, Lone S.;

    2011-01-01

    Nitrate and pesticide leaching led to the designation of groundwater protection zones in Denmark. The protective measures in these zones often clash with local interests in agriculture. Scenarios were used to evaluate the development of a groundwater protection zone in a farming area. Stakeholders...... are accorded strong influence on the scenarios. Scenario inputs comprised land cover, land use and farmers' plans and preferences, as registered in interviews with farmers. Scenarios were evaluated regarding the effect on nitrate leaching, extent of pesticide-free area and farm income. The scenarios proved...... effective in modelling coupled development in land use/land cover and nitrate leaching and pesticide-free area. Voluntary commitment to schemes, calculated according to stakeholder preferences, reduced nitrate leaching by up to 15%. Scenarios with additional inputs from experts who formulated more...

  17. The Shape of Things to Come: Swedish Developments on the Protection of Privacy

    Directory of Open Access Journals (Sweden)

    Rebecca Wong

    2005-03-01

    Full Text Available The article highlights the tensions that exist in the protection of privacy online in Sweden following the enactment of the Personal Data Act in 1998. It raises the question whether the Data Protection Directive 95/46/EC is outdated (complementing the Directive on Privacy and Electronic Communications 2002/58/EC and whether it necessitates a review in the light of current online developments. The problem with dealing with the protection of privacy online as a national solution, such as Sweden does, is that the pervasive application of personal data in the cyberspace environment is a global problem requiring solutions that are not confined within the national borders. This article will consider the Swedish developments and raise the debate about the need for a global dialogue not confined within the European Union, but one that engages other countries such as the United States.

  18. Study on decision making of ecological environment protection and sustainable development based on measurement and assessment

    Science.gov (United States)

    Liu, Yan-fang; Niu, Ji-qiang; Hu, Chang-jie; Liu, Yao-lin; Nong, Yu; Wei, Li-jun

    2008-10-01

    The key problem for implementation of the sustainable development is to design the strategy and policy which incorporates the environmental impacts. This paper puts forward a new model about decision making of ecological environment protection and sustainable development based on estimating and assessment. The environmental carrying capacity and developing intensity of studied area are analyzed, the ecological security and the level of sustainable development are evaluated, and also the constraints are discussed. According to this analysis, the range of Lichuan is divided into four regions. On the foundation of distinctive characteristics of each area, the designation of the industrial development and environment protection have been ensured; after that, the environmental impact of the given strategies has been identified and predicted; finally, several mitigation measures are suggested.

  19. Environmental Protection Legislation on China’s Energy Development and In-situ Conversion

    Institute of Scientific and Technical Information of China (English)

    NAN Jing-yu

    2012-01-01

    China’s poor energy development and in-situ conversion legislation, environment laws and energy laws lead to a severe environmental issue in energy source. This paper uses comparison and logical methods to discuss Chapter 4 of Energy Law (Draft for Soliciting Opinions). Energy development is taken as a separate chapter; in-situ energy conversion is added to energy processing and conversion, common features are summarized to form general provisions and other provisions. According to respective characteristics of system for total amount control of energy development, performance guarantee system, environmental trust fund system, energy retaining system and environmental lien system, incorporate them into energy development, in-situ energy conversion and energy processing and conversion, in the hope of solving China’s shortage of supply for environmental protection laws on energy development and in-situ conversion, responding to times of environmental protection, and optimizing China’s Energy Law.

  20. The orphan adapter protein SLY1 as a novel anti-apoptotic protein required for thymocyte development

    Directory of Open Access Journals (Sweden)

    Beer-Hammer Sandra

    2009-07-01

    Full Text Available Abstract Background SH3 containing Lymphocyte Protein (SLY1 is a putative adapter protein exclusively expressed in lymphocytes which is involved in antigen receptor induced activation. We previously have generated SLY1Δ/Δ mice harbouring a partial deletion in the N-terminal region of SLY1 which revealed profound immunological defects in T and B cell functions. Results In this study, T cell development in SLY1-/- and SLY1Δ/Δ mice was analysed ex vivo and upon cultivation with the bone marrow stromal cell line OP9. SLY1-deficient thymocytes were compromised in inducing nutrient receptor expression and ribosomal protein S6 phosphorylation, indicating a defect in mTOR complex activation. Furthermore, SLY1 was identified as a novel anti-apoptotic protein required for developmental progression of T cell precursors to the CD4+CD8+ double-positive stage by protecting from premature programmed cell death initiation in developing CD4-CD8- double-negative thymocytes. In addition, SLY1 phosphorylation was differentially regulated upon Notch ligand-mediated stimulation and expression of the preTCR. Conclusion Thus, our results suggest a non-redundant role for SLY1 in integrating signals from both receptors in early T cell progenitors in the thymus.

  1. Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.

    Directory of Open Access Journals (Sweden)

    Emily L Lowe

    Full Text Available Inflammatory bowel disease (IBD is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but thought to result from a dysregulated adaptive and innate immune response to microbial products in a genetically susceptible host. Toll-like receptor (TLR signaling induced by intestinal commensal bacteria plays a crucial role in maintaining intestinal homeostasis, innate immunity and the enhancement of intestinal epithelial cell (IEC integrity. However, the role of TLR2 in the development of colorectal cancer has not been studied. We utilized the AOM-DSS model for colitis-associated colorectal cancer (CAC in wild type (WT and TLR2(-/- mice. Colons harvested from WT and TLR2(-/- mice were used for histopathology, immunohistochemistry, immunofluorescence and cytokine analysis. Mice deficient in TLR2 developed significantly more and larger colorectal tumors than their WT controls. We provide evidence that colonic epithelium of TLR2(-/- mice have altered immune responses and dysregulated proliferation under steady-state conditions and during colitis, which lead to inflammatory growth signals and predisposition to accelerated neoplastic growth. At the earliest time-points assessed, TLR2(-/- colons exhibited a significant increase in aberrant crypt foci (ACF, resulting in tumors that developed earlier and grew larger. In addition, the intestinal microenvironment revealed significantly higher levels of IL-6 and IL-17A concomitant with increased phospho-STAT3 within ACF. These observations indicate that in colitis, TLR2 plays a protective role against the development of CAC.

  2. Toll-like receptor 2 signaling protects mice from tumor development in a mouse model of colitis-induced cancer.

    Science.gov (United States)

    Lowe, Emily L; Crother, Timothy R; Rabizadeh, Shervin; Hu, Bing; Wang, Hanlin; Chen, Shuang; Shimada, Kenichi; Wong, Michelle H; Michelsen, Kathrin S; Arditi, Moshe

    2010-09-27

    Inflammatory bowel disease (IBD) is a disorder of chronic inflammation with increased susceptibility to colorectal cancer. The etiology of IBD is unclear but thought to result from a dysregulated adaptive and innate immune response to microbial products in a genetically susceptible host. Toll-like receptor (TLR) signaling induced by intestinal commensal bacteria plays a crucial role in maintaining intestinal homeostasis, innate immunity and the enhancement of intestinal epithelial cell (IEC) integrity. However, the role of TLR2 in the development of colorectal cancer has not been studied. We utilized the AOM-DSS model for colitis-associated colorectal cancer (CAC) in wild type (WT) and TLR2(-/-) mice. Colons harvested from WT and TLR2(-/-) mice were used for histopathology, immunohistochemistry, immunofluorescence and cytokine analysis. Mice deficient in TLR2 developed significantly more and larger colorectal tumors than their WT controls. We provide evidence that colonic epithelium of TLR2(-/-) mice have altered immune responses and dysregulated proliferation under steady-state conditions and during colitis, which lead to inflammatory growth signals and predisposition to accelerated neoplastic growth. At the earliest time-points assessed, TLR2(-/-) colons exhibited a significant increase in aberrant crypt foci (ACF), resulting in tumors that developed earlier and grew larger. In addition, the intestinal microenvironment revealed significantly higher levels of IL-6 and IL-17A concomitant with increased phospho-STAT3 within ACF. These observations indicate that in colitis, TLR2 plays a protective role against the development of CAC.

  3. The development of a method to measure speed adaptation to traffic complexity: Identifying novice, unsafe, and overconfident drivers.

    NARCIS (Netherlands)

    Craen, S. de Twisk, D.A.M. Hagenzieker, M.P. Elffers, H. & Brookhuis, K.A.

    2008-01-01

    To monitor novice driver performance in the first years of solo driving, a test aimed at assessing speed adaptation to the traffic situation was developed and evaluated. The Adaptation Test consisted of 18 traffic scenes presented in two (almost) identical photographs, which differed in one single d

  4. Workshop approach for developing climate change adaptation strategies and actions for natural resource management agencies in the United States

    Science.gov (United States)

    Jessica E. Halofsky; David L Peterson; Michael J. Furniss; Linda A. Joyce; Constance I. Millar; Ronald P. Neilson

    2011-01-01

    Concrete ways to adapt to climate change are needed to help land-management agencies take steps to incorporate climate change into management and take advantage of opportunities to balance the negative effects of climate change. Because the development of adaptation tools and strategies is at an early stage, it is important that ideas and strategies are disseminated...

  5. Climate change adaptation in Ethiopia

    DEFF Research Database (Denmark)

    Weldegebriel, Zerihun Berhane; Prowse, Martin

    Ethiopia is vulnerable to climate change due to its limited development and dependence on agriculture. Social protection schemes like the Productive Safety Net Programme (PSNP) can play a positive role in promoting livelihoods and enhancing households’ risk management. This article examines......, they suggest the PSNP may not be helping smallholders diversify income sources in a positive manner for climate adaptation. The article concludes by arguing for further investigation of the PSNP’s influence on smallholders’ adaptation strategies....

  6. Climate change adaptation in Ethiopia

    DEFF Research Database (Denmark)

    Weldegebriel, Zerihun Berhane; Prowse, Martin

    Ethiopia is vulnerable to climate change due to its limited development and dependence on agriculture. Social protection schemes like the Productive Safety Net Programme (PSNP) can play a positive role in promoting livelihoods and enhancing households’ risk management. This article examines......, they suggest the PSNP may not be helping smallholders diversify income sources in a positive manner for climate adaptation. The article concludes by arguing for further investigation of the PSNP’s influence on smallholders’ adaptation strategies....

  7. Developing and Implementing Climate Change Adaptation Options in Forest Ecosystems: A Case Study in Southwestern Oregon, USA

    OpenAIRE

    Jessica E. Halofsky; Peterson, David L.; Kerry L. Metlen; M. Gwyneth Myer; V. Alaric Sample

    2016-01-01

    Climate change will likely have significant effects on forest ecosystems worldwide. In Mediterranean regions, such as that in southwestern Oregon, USA, changes will likely be driven mainly by wildfire and drought. To minimize the negative effects of climate change, resource managers require tools and information to assess climate change vulnerabilities and to develop and implement adaptation actions. We developed an approach to facilitate development and implementation of climate change adapt...

  8. Development of Curricula for Nuclear Radiation Protection, Nuclear Instrumentation, and Nuclear Materials Processing Technologies. Final Report.

    Science.gov (United States)

    Hull, Daniel M.

    A study was conducted to assist two-year postsecondary educational institutions in providing technical specialty courses for preparing nuclear technicians. As a result of project activities, curricula have been developed for five categories of nuclear technicians and operators: (1) radiation protection technician, (2) nuclear instrumentation and…

  9. Regulatory gene networks that shape the development of adaptive phenotypic plasticity in a cichlid fish.

    Science.gov (United States)

    Schneider, Ralf F; Li, Yuanhao; Meyer, Axel; Gunter, Helen M

    2014-09-01

    Phenotypic plasticity is the ability of organisms with a given genotype to develop different phenotypes according to environmental stimuli, resulting in individuals that are better adapted to local conditions. In spite of their ecological importance, the developmental regulatory networks underlying plastic phenotypes often remain uncharacterized. We examined the regulatory basis of diet-induced plasticity in the lower pharyngeal jaw (LPJ) of the cichlid fish Astatoreochromis alluaudi, a model species in the study of adaptive plasticity. Through raising juvenile A. alluaudi on either a hard or soft diet (hard-shelled or pulverized snails) for between 1 and 8 months, we gained insight into the temporal regulation of 19 previously identified candidate genes during the early stages of plasticity development. Plasticity in LPJ morphology was first detected between 3 and 5 months of diet treatment. The candidate genes, belonging to various functional categories, displayed dynamic expression patterns that consistently preceded the onset of morphological divergence and putatively contribute to the initiation of the plastic phenotypes. Within functional categories, we observed striking co-expression, and transcription factor binding site analysis was used to examine the prospective basis of their coregulation. We propose a regulatory network of LPJ plasticity in cichlids, presenting evidence for regulatory crosstalk between bone and muscle tissues, which putatively facilitates the development of this highly integrated trait. Through incorporating a developmental time-course into a phenotypic plasticity study, we have identified an interconnected, environmentally responsive regulatory network that shapes the development of plasticity in a key innovation of East African cichlids.

  10. Community Vitality: The Role of Community-Level Resilience Adaptation and Innovation in Sustainable Development

    Directory of Open Access Journals (Sweden)

    Lenore Newman

    2010-01-01

    Full Text Available Community level action towards sustainable development has emerged as a key scale of intervention in the effort to address our many serious environmental issues. This is hindered by the large-scale destruction of both urban neighbourhoods and rural villages in the second half of the twentieth century. Communities, whether they are small or large, hubs of experimentation or loci of traditional techniques and methods, can be said to have a level of community vitality that acts as a site of resilience, adaptation and innovation in the face of environmental challenges. This paper outlines how community vitality acts as a cornerstone of sustainable development and suggests some courses for future research. A meta-case analysis of thirty-five Canadian communities reveals the characteristics of community vitality emerging from sustainable development experiments and its relationship to resilience, applied specifically to community development.

  11. Quality of Life in Depression Scale (QLDS – development of the scale and Polish adaptation

    Directory of Open Access Journals (Sweden)

    Majkowicz, Mikołaj

    2013-07-01

    Full Text Available Aim. The aim of this study was to adapt the Quality of Life in Depression Scale to Polish conditions. The scale determines the quality of life, defined in terms of the concept of needs, and focuses on patients with depressive disorders. Since its basic version has been developed, the tool was adapted in many countries, also outside Europe.Method. The adaptation procedure included the translation of the original version into Polish, followed by the English retranslation, and was performed by four independent, qualified translators. The final Polish version was verified during a pilot study.Results. This pilot study confirmed high reliability of the Polish version of Quality of Life in Depression Scale.Conclusion. The Quality of Life in Depression Scale (QLDS can be considered an interesting tool in view of its broad theoretical background, and a simple procedure to complete during a clinical evaluation. The use of a specialist translation procedure, and the results of our pilot study suggest that the QLDS can be used in further research, both when evaluating a clinical population and when dealing with individual patients.

  12. Context-dependent player's movement interpretation: application to adaptive game development

    Science.gov (United States)

    Picard, Francois; Estraillier, Pascal

    2010-02-01

    Video games are more and more controlled by the real movements of the player. However, the player is constrained by the system devices, imposing a limited vocabulary of actions associated with a set of unnatural movements. To introduce more entertaining video games to players, a component-based architecture is proposed. It has been acknowledged as the starting point for the development of adaptive applications based on the hypothesis of a high level dialogue between the system and the player. The system adaptability relies on interpretation mechanisms of the player behaviors. These behaviors are defined through the representation of the real movements of the player who freely interacts with the 3D elements composing an immersive virtual environment, following a given game scenario. The efficient interpretation of the player movements relies on the introduction in the system of the management of the scene's context. The contextual information not only helps to determine the true meaning of an observed behavior but also makes the system to adapt its processes regarding this interpretation, while managing its hardware and software resources efficiently. A commercial motion capture interface has been enhanced by the elaboration of such a system.

  13. The Dendrobium catenatum Lindl. genome sequence provides insights into polysaccharide synthase, floral development and adaptive evolution.

    Science.gov (United States)

    Zhang, Guo-Qiang; Xu, Qing; Bian, Chao; Tsai, Wen-Chieh; Yeh, Chuan-Ming; Liu, Ke-Wei; Yoshida, Kouki; Zhang, Liang-Sheng; Chang, Song-Bin; Chen, Fei; Shi, Yu; Su, Yong-Yu; Zhang, Yong-Qiang; Chen, Li-Jun; Yin, Yayi; Lin, Min; Huang, Huixia; Deng, Hua; Wang, Zhi-Wen; Zhu, Shi-Lin; Zhao, Xiang; Deng, Cao; Niu, Shan-Ce; Huang, Jie; Wang, Meina; Liu, Guo-Hui; Yang, Hai-Jun; Xiao, Xin-Ju; Hsiao, Yu-Yun; Wu, Wan-Lin; Chen, You-Yi; Mitsuda, Nobutaka; Ohme-Takagi, Masaru; Luo, Yi-Bo; Van de Peer, Yves; Liu, Zhong-Jian

    2016-01-12

    Orchids make up about 10% of all seed plant species, have great economical value, and are of specific scientific interest because of their renowned flowers and ecological adaptations. Here, we report the first draft genome sequence of a lithophytic orchid, Dendrobium catenatum. We predict 28,910 protein-coding genes, and find evidence of a whole genome duplication shared with Phalaenopsis. We observed the expansion of many resistance-related genes, suggesting a powerful immune system responsible for adaptation to a wide range of ecological niches. We also discovered extensive duplication of genes involved in glucomannan synthase activities, likely related to the synthesis of medicinal polysaccharides. Expansion of MADS-box gene clades ANR1, StMADS11, and MIKC(*), involved in the regulation of development and growth, suggests that these expansions are associated with the astonishing diversity of plant architecture in the genus Dendrobium. On the contrary, members of the type I MADS box gene family are missing, which might explain the loss of the endospermous seed. The findings reported here will be important for future studies into polysaccharide synthesis, adaptations to diverse environments and flower architecture of Orchidaceae.

  14. Development Protected Cultivation in Horticulture Product: Feasibility Analysis in West Java Province

    Directory of Open Access Journals (Sweden)

    Nita Kuswardhani

    2014-01-01

    Full Text Available The development of agricultural system cannot be solved only through technological changes  but also necessary to change the strategy of agricultural system as a whole. The aim of this research was to assess the factor of  strengths, weaknesses, opportunities and threats (SWOT analysis that can be used to identify relevant economic, ecological and societal (EES issues for the assessment of sustainable development in protected cultivation in West Java Province. The potential of protected cultivation was higher energy productivity than open field production, indirect energy and renewable energy were the main source of energy. The ratio of output to input energy was higher in greenhouse production (0.85, 0.45 and 0.49 than open field (OF vegetable production (0.52, 0.175 and 0.186 for tomato, and chili. Financial analysis revealed higher mean net returns from greenhouse vegetable production as 7043 $/ha (922-15,299 $/ha when compared to 563 $/ha (43-1,172 $/ha from open field vegetable production. Among the greenhouse vegetables, tomato cultivation was the most profitable in terms of energy efficiency and financial productivity. Generally, reducing pest and disease in vegetable production is a main expectation from newly adopted technology. Limited land holding size of agricultural fields, high capital investment and lack of infrastructure were the constraints in improving their production through new technology. Low price of the product and lack of adequate market were also the other problems with vegetable production. Inadequate government support in term of training and financial support to farmers in certain areas make it difficult in protected cultivation technology. Capacity building of farmers, research and development on protected cultivation, manufacturing and financial sector support, supporting an efficient and adequate marketing system of protected cultivation product, and development of an agribusiness area especially for export

  15. Effective methods of consumer protection in Brazil. An analysis in the context of property development contracts

    Directory of Open Access Journals (Sweden)

    Deborah Alcici Salomão

    2015-12-01

    Full Text Available This study examines consumer protection in arbitration, especially under the example of property development contract disputes in Brazil. This is a very current issue in light of the presidential veto of consumer arbitration on May 26, 2015. The article discusses the arbitrability of these disputes based on Brazilian legislation and relevant case law. It also analyzes of the advantages, disadvantages and trends of consumer arbitration in the context of real estate contracts. The paper concludes by providing suggestions specific to consumer protection in arbitration based on this analysis.

  16. Collective Protection Factors Methodology Development Using High Concentration Polydisperse Inert Aerosols: Results of FY09 Testing

    Science.gov (United States)

    2012-04-01

    As a consequence of the first use of chemical warfare agents in World War I, the U.S. Military has endeavored to find adequate protection against the...of chlorine and mustard agent gases in World War I, there has been progressive development in the methods and equipment used for protecting personnel...45 E o 8 c o <-» a 2 50 45 in 35 30 25 20 15 in 5 Front Dust Irak 3 V APS Rear \\y rW - fi *?*lai

  17. Development of higher-ranking standards with respect to fire protection for nuclear facilities in the area decommissioning and disposal; Entwicklung eines uebergeordneten Standards im Hinblick auf Brandschutzmassnahmen fuer kerntechnische Anlagen im Bereich Stilllegung und Entsorgung

    Energy Technology Data Exchange (ETDEWEB)

    Mummert, Maxi; Sonneborn, Volker; Dilger, Matthias; Traichel, Anke [NUKEM Technologies GmbH, Alzenau (Germany). Safety Engineering and Assessment

    2013-07-01

    In the frame of NPP decommissioning and dismantling besides operational waste the large components have to be processes. The licensing of conditioning and storage facilities at the site requires the fulfillment of protection targets, especially the protection of the public and the environment from radioactivity. This contribution deals with the fire as internal incident. The analysis includes deterministic and probabilistic methods. The project is aimed to the development of a fire protection concept according differing national requirements and the adaption of a probabilistic fire risk analysis for non-reactor nuclear facilities.

  18. Peripheral NK cell phenotypes: multiple changing of faces of an adapting, developing cell.

    Science.gov (United States)

    Perussia, Bice; Chen, Yingying; Loza, Matthew J

    2005-02-01

    We have defined the existence of developmental relationships among human peripheral NK cells with distinct phenotypic and functional characteristics. These findings closely parallel the changes that occur in vivo during NK cell development, and in vitro in experimental culture systems supporting NK cell generation from hematopoietic progenitors. These new insights provide a simplified framework to understand NK cell immunobiology and the cellular bases for their roles in innate immunity, initiation and maintenance of immune responses via regulation of adaptive and accessory cell functions, and immune pathologies.

  19. Improving the use of research evidence in guideline development: 13. Applicability, transferability and adaptation

    Directory of Open Access Journals (Sweden)

    Oxman Andrew D

    2006-12-01

    Full Text Available Abstract Background The World Health Organization (WHO, like many other organisations around the world, has recognised the need to use more rigorous processes to ensure that health care recommendations are informed by the best available research evidence. This is the thirteenth of a series of 16 reviews that have been prepared as background for advice from the WHO Advisory Committee on Health Research to WHO on how to achieve this. Objectives We reviewed the literature on applicability, transferability, and adaptation of guidelines. Methods We searched five databases for existing systematic reviews and relevant primary methodological research. We reviewed the titles of all citations and retrieved abstracts and full text articles if the citations appeared relevant to the topic. We checked the reference lists of articles relevant to the questions and used snowballing as a technique to obtain additional information. We used the definition "coming from, concerning or belonging to at least two or all nations" for the term international. Our conclusions are based on the available evidence, consideration of what WHO and other organisations are doing and logical arguments. Key questions and answers We did not identify systematic reviews addressing the key questions. We found individual studies and projects published in the peer reviewed literature and on the Internet. Should WHO develop international recommendations? • Resources for developing high quality recommendations are limited. Internationally developed recommendations can facilitate access to and pooling of resources, reduce unnecessary duplication, and involve international scientists. • Priority should be given to international health problems and problems that are important in low and middle-income countries, where these advantages are likely to be greatest. • Factors that influence the transferability of recommendations across different settings should be considered systematically and

  20. Fostering the Development of Master Adaptive Learners: A Conceptual Model to Guide Skill Acquisition in Medical Education.

    Science.gov (United States)

    Cutrer, William B; Miller, Bonnie; Pusic, Martin V; Mejicano, George; Mangrulkar, Rajesh S; Gruppen, Larry D; Hawkins, Richard E; Skochelak, Susan E; Moore, Donald E

    2017-01-01

    Change is ubiquitous in health care, making continuous adaptation necessary for clinicians to provide the best possible care to their patients. The authors propose that developing the capabilities of a Master Adaptive Learner will provide future physicians with strategies for learning in the health care environment and for managing change more effectively. The concept of a Master Adaptive Learner describes a metacognitive approach to learning based on self-regulation that can foster the development and use of adaptive expertise in practice. The authors describe a conceptual literature-based model for a Master Adaptive Learner that provides a shared language to facilitate exploration and conversation about both successes and struggles during the learning process.

  1. Protected Areas' Impacts on Brazilian Amazon Deforestation: Examining Conservation-Development Interactions to Inform Planning.

    Directory of Open Access Journals (Sweden)

    Alexander Pfaff

    Full Text Available Protected areas are the leading forest conservation policy for species and ecoservices goals and they may feature in climate policy if countries with tropical forest rely on familiar tools. For Brazil's Legal Amazon, we estimate the average impact of protection upon deforestation and show how protected areas' forest impacts vary significantly with development pressure. We use matching, i.e., comparisons that are apples-to-apples in observed land characteristics, to address the fact that protected areas (PAs tend to be located on lands facing less pressure. Correcting for that location bias lowers our estimates of PAs' forest impacts by roughly half. Further, it reveals significant variation in PA impacts along development-related dimensions: for example, the PAs that are closer to roads and the PAs closer to cities have higher impact. Planners have multiple conservation and development goals, and are constrained by cost, yet still conservation planning should reflect what our results imply about future impacts of PAs.

  2. Real-time Model Development of Core Protection and Monitoring System for SMART Simulator Application

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Bonseung; Hwang, Daehyun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2013-05-15

    Important features of the software models are described for the application to SMART simulator. A real-time performance of the models was examined for various simulation scenarios. Areal-time model development of core protection and monitoring algorithms for SMART simulator is being studied. Software algorithms as well as design bases and requirements for core protection and monitoring are developed and various performance tests are done. From test results, it is judged that SCOPS{sub S}SIM and SCOMS{sub S}SIM algorithms and calculational capabilities are appropriate for core protection and monitoring program in SMART simulator. A multi-purpose best-estimate simulator for the SMART is being established which is purposed to be used as a tool to evaluate the impacts of design changes on the safety performance, and to improve and/or optimize the operating procedure of the SMART. In keeping with these purposes, a real-time model of the digital core protection and monitoring systems was developed on the basis of SCOPS and SCOMS algorithms of SMART.

  3. Development status on the real-time controller for solar multi-conjugate adaptive optics system

    Science.gov (United States)

    Kong, Lin; Zhu, Lei; Rao, Changhui

    2016-10-01

    Solar observations are performed over an extended field of view (FoV) and the isoplanatic patch which conventional adaptive optics (AO) provides diffraction limited resolution is a severe limitation. Multi-conjugate Adaptive Optics (MCAO) can be used to extend the corrected FoV of AO system. Compared to AO, MCAO which usually utilizes a wide-field Shack-Hartmann wavefront sensor to control multiple deformable mirrors(DMs) is more complicated. Because the Sun is an extended object, correlation algorithms are applied to detect gradients in solar MCAO system. Moreover, due to the fast evolving daytime seeing conditions and the fact that much science has to be done at visible wavelengths, a very high closed-loop bandwidth is also required. The computation and delay development of the real-time controller (RTC) in solar MCAO system is more challenging than that in night-time MCAO system. This paper reviews the solar MCAO techniques and systems in the world, especially emphasizes the framework and implementation of the RTC. The development of MCAO in China is also introduced. An outlook of the RTC for the solar MCAO system in development is given.

  4. Adoption, adaptation, and abandonment: Appropriation of science education professional development learning

    Science.gov (United States)

    Longhurst, Max L.

    Understanding factors that impact teacher utilization of learning from professional development is critical in order maximize the educational and financial investment in teacher professional learning. This study used a multicase mixed quantitative and qualitative methodology to investigate the factors that influence teacher adoption, adaption, or abandonment of learning from science teacher professional development. The theoretical framework of activity theory was identified as a useful way to investigate the phenomenon of teacher appropriation of pedagogical practices from professional development. This framework has the capacity to account for a multitude of elements in the context of a learning experience. In this study educational appropriation is understood through a continuum of how an educator acquires and implements both practical and conceptual aspects of learning from professional development within localized context. The variability associated with instructional changes made from professional development drives this inquiry to search for better understandings of the appropriation of pedagogical practices. Purposeful sampling was used to identify two participants from a group of eighth-grade science teachers engaged in professional development designed to investigate how cyber-enabled technologies might enhance instruction and learning in integrated science classrooms. The data from this investigation add to the literature of appropriation of instructional practices by connecting eight factors that influence conceptual and practical tools with the development of ownership of pedagogical practices in the appropriation hierarchy. Recommendations are shared with professional development developers, providers, and participants in anticipation that future science teaching experiences might be informed by findings from this study.

  5. On the Development of Radio Astronomy and Protected Astronomy Reserves in South Africa

    Science.gov (United States)

    Tiplady, Adrian John

    2015-08-01

    Recent initiatives to take advantage of various geographic locations in South Africa that exhibit excellent conditions for astronomical observations (optical and radio) has resulted in the establishment of a number of world class astronomical facilities. This includes the 10m class Southern African Large Telescope, the 64 dish MeerKAT radio telescope (under construction), and future Square Kilometre Array.To preserve these areas that exhibit natural astronomical advantage, unique legislation was promulgated to establish 'astronomy reserves'. These reserves are protected through a unique set of regulations that enable protection of astronomical facilities located in declared areas from any current, and future, sources of potential interference. This paper will look at the development and implementation of a protection regime, and review some of practical implications of the construction and operation of a radio telescope in what has become to be known as a 'radio quiet zone'.

  6. Developments in Genetic and Epigenetic Data Protection in Behavioral and Mental Health Spaces.

    Science.gov (United States)

    Terry, Nicolas

    2015-10-01

    The legal system has been preparing for an explosion of epigenetic issues in public health, environmental regulation and litigation. So far, this explosion has been muted, and for now epigenetic data protection merely seems to be "enjoying" the same technological and legal challenges experienced by other clinical and research data. However, three areas of development suggest where epigenetic data protection may prove problematic. This article examines these three issues, noting the rapid expansion of research based on EMR-sourced clinical data, the large number of data protection models that can apply to genetic data (including point-of-use prohibitions on discrimination and confidentiality), and the increasing and controversial dangers of deidentified information being reidentified.

  7. Key Technologies Development of Transient Signals Based Protection Device Using DSP and S-Transform

    Science.gov (United States)

    Liu, Xingmao; Zheng, Gao

    2017-05-01

    The correctness of new principle of transient signal based protection used to be verified by simulating. In order to further introduce the dynamic simulation experiments for the transient signal based protection algorithm, the key technologies of transient signal based protection device were developed. The hardware of the synchronous multi-channel data acquisition and high-speed data processing was designed with kernel of high speed floating point digital signal processor TMS320C6748 and simultaneous sampling analog-to-digital converter. The sampling program reads the AD conversion data using DMA mode, which reduce the consumption of CPU time. The S transform was used to extract the fault traveling wave signals from the sampled data. The time consumption of algorithm which extract the traveling wave was analyzed when it ran on TMS320C6748. The test result shows that the hardware and software design is feasible.

  8. A Framework for the Development of Context-Adaptable User Interfaces for Ubiquitous Computing Systems

    Directory of Open Access Journals (Sweden)

    Gervasio Varela

    2016-07-01

    Full Text Available This paper addresses the problem of developing user interfaces for Ubiquitous Computing (UC and Ambient Intelligence (AmI systems. These kind of systems are expected to provide a natural user experience, considering interaction modalities adapted to the user abilities and preferences and using whatever interaction devices are present in the environment. These interaction devices are not necessarily known at design time. The task is quite complicated due to the variety of devices and technologies, and the diversity of scenarios, and it usually burdens the developer with the need to create many different UIs in order to consider the foreseeable user-environment combinations. Here, we propose an UI abstraction framework for UC and AmI systems that effectively improves the portability of those systems between different environments and for different users. It allows developers to design and implement a single UI capable of being deployed with different devices and modalities regardless the physical location.

  9. Adaptive and repeated cumulative meta-analyses of safety data during a new drug development process.

    Science.gov (United States)

    Quan, Hui; Ma, Yingqiu; Zheng, Yan; Cho, Meehyung; Lorenzato, Christelle; Hecquet, Carole

    2015-01-01

    During a new drug development process, it is desirable to timely detect potential safety signals. For this purpose, repeated meta-analyses may be performed sequentially on accumulating safety data. Moreover, if the amount of safety data from the originally planned program is not enough to ensure adequate power to test a specific hypothesis (e.g., the noninferiority hypothesis of an event of interest), the total sample size may be increased by adding new studies to the program. Without appropriate adjustment, it is well known that the type I error rate will be inflated because of repeated analyses and sample size adjustment. In this paper, we discuss potential issues associated with adaptive and repeated cumulative meta-analyses of safety data conducted during a drug development process. We consider both frequentist and Bayesian approaches. A new drug development example is used to demonstrate the application of the methods.

  10. Development Of A Computer-Adaptive Version Of The Forgotten Joint Score

    Science.gov (United States)

    Giesinger, Johannes M.; Kuster, Markus S.; Holzner, Bernhard; Giesinger, Karlmeinrad

    2013-01-01

    Patient-reported outcomes (PROs) are an important endpoint in orthopedics providing comprehensive information about patients' perspectives on treatment outcome. Computer-adaptive test (CAT) measures are an advanced method for assessing PROs using item sets that are tailored to the individual patient. This provides increased measurement precision and reduces the number of items. We developed a CAT version of the Forgotten Joint Score (FJS), a measure of joint awareness in everyday life. CAT development was based on FJS data from 580 patients after THA or TKA (808 assessments). The CAT version reduced the number of items by half at comparable measurement precision. In a feasibility study we administered the newly developed CAT measure on tablet PCs and found that patients actually preferred electronic questionnaires over paper–pencil questionnaires. PMID:23219089

  11. A Framework for the Development of Context-Adaptable User Interfaces for Ubiquitous Computing Systems.

    Science.gov (United States)

    Varela, Gervasio; Paz-Lopez, Alejandro; Becerra, Jose A; Duro, Richard

    2016-07-07

    This paper addresses the problem of developing user interfaces for Ubiquitous Computing (UC) and Ambient Intelligence (AmI) systems. These kind of systems are expected to provide a natural user experience, considering interaction modalities adapted to the user abilities and preferences and using whatever interaction devices are present in the environment. These interaction devices are not necessarily known at design time. The task is quite complicated due to the variety of devices and technologies, and the diversity of scenarios, and it usually burdens the developer with the need to create many different UIs in order to consider the foreseeable user-environment combinations. Here, we propose an UI abstraction framework for UC and AmI systems that effectively improves the portability of those systems between different environments and for different users. It allows developers to design and implement a single UI capable of being deployed with different devices and modalities regardless the physical location.

  12. Education for Sustainable Development: Enhancing Climate Change Adaptation Expertise in Developing Countries

    Science.gov (United States)

    Fahey, Shireen; Verstraten, Luke; Berry, Ashton J.

    2016-01-01

    This article presents the results of an innovative education capacity assessment and delivery project to promote sustainable development in large ocean states in the Western Indian Ocean (WIO) region. Science education can help prepare the present and coming generations for stability in an uncertain future. Limited financial, geographical and…

  13. Education for Sustainable Development: Enhancing Climate Change Adaptation Expertise in Developing Countries

    Science.gov (United States)

    Fahey, Shireen; Verstraten, Luke; Berry, Ashton J.

    2016-01-01

    This article presents the results of an innovative education capacity assessment and delivery project to promote sustainable development in large ocean states in the Western Indian Ocean (WIO) region. Science education can help prepare the present and coming generations for stability in an uncertain future. Limited financial, geographical and…

  14. Development of an Adaptable Display and Diagnostic System for the Evaluation of Tropical Cyclone Forecasts

    Science.gov (United States)

    Kucera, P. A.; Burek, T.; Halley-Gotway, J.

    2015-12-01

    NCAR's Joint Numerical Testbed Program (JNTP) focuses on the evaluation of experimental forecasts of tropical cyclones (TCs) with the goal of developing new research tools and diagnostic evaluation methods that can be transitioned to operations. Recent activities include the development of new TC forecast verification methods and the development of an adaptable TC display and diagnostic system. The next generation display and diagnostic system is being developed to support evaluation needs of the U.S. National Hurricane Center (NHC) and broader TC research community. The new hurricane display and diagnostic capabilities allow forecasters and research scientists to more deeply examine the performance of operational and experimental models. The system is built upon modern and flexible technology that includes OpenLayers Mapping tools that are platform independent. The forecast track and intensity along with associated observed track information are stored in an efficient MySQL database. The system provides easy-to-use interactive display system, and provides diagnostic tools to examine forecast track stratified by intensity. Consensus forecasts can be computed and displayed interactively. The system is designed to display information for both real-time and for historical TC cyclones. The display configurations are easily adaptable to meet the needs of the end-user preferences. Ongoing enhancements include improving capabilities for stratification and evaluation of historical best tracks, development and implementation of additional methods to stratify and compute consensus hurricane track and intensity forecasts, and improved graphical display tools. The display is also being enhanced to incorporate gridded forecast, satellite, and sea surface temperature fields. The presentation will provide an overview of the display and diagnostic system development and demonstration of the current capabilities.

  15. Algorithm Design and Validation for Adaptive Nonlinear Control Enhancement (ADVANCE) Technology Development for Resilient Flight Control Project

    Data.gov (United States)

    National Aeronautics and Space Administration — SSCI proposes to develop and test a framework referred to as the ADVANCE (Algorithm Design and Validation for Adaptive Nonlinear Control Enhancement), within which...

  16. Progress Report for "Developing a Proactive Framework for Adaptive Management of Chronic Wasting Disease on the National Elk Refuge"

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Hobbs, Monello, and Kauffman have been granted funds to develop a Bayesian state space model to support adaptive management of Chronic Wasting Disease (CWD) in the...

  17. Development and flight qualification of the C-SiC thermal protection systems for the IXV

    Science.gov (United States)

    Buffenoir, François; Zeppa, Céline; Pichon, Thierry; Girard, Florent

    2016-07-01

    The Intermediate experimental Vehicle (IXV) atmospheric re-entry demonstrator, developed within the FLPP (Future Launcher Preparatory Programme) and funded by ESA, aimed at developing a demonstration vehicle that gave Europe a unique opportunity to increase its knowledge in the field of advanced atmospheric re-entry technologies. A key technology that has been demonstrated in real conditions through the flight of this ambitious vehicle is the thermal protection system (TPS) of the Vehicle. Within this programme, HERAKLES, Safran Group, has been in charge of the TPS of the windward and nose assemblies of the vehicle, and has developed and manufactured SepcarbInox® ceramic matrix composite (CMC) protection systems that provided a high temperature resistant non ablative outer mould line (OML) for enhanced aerodynamic control. The design and flight justification of these TPS has been achieved through extensive analysis and testing:

  18. Development of innovative architecture of the organizational and economic mechanism for the nature protection management

    Science.gov (United States)

    Mikhailov, V. G.; Kiseleva, T. V.; Karasev, V. A.; Mikhailov, G. S.; Skukin, V. A.

    2017-05-01

    The problems of the efficient functioning of environmental and economic systems of various levels on the basis of the adequate organizational and economic management mechanism are considered in the article. The purpose of the study is the analysis and development of theoretical provisions for the formation of a modern, innovative organizational and economic mechanism of the nature protection management. The compliance matrix of the innovative elements presented in the structure of the organizational and economic mechanism of the nature protection management is developed. The main result of the study is the improvement of the existing management mechanism to minimize the negative impact on the environment, including through the incentive system, and to improve the financial performance of the economic entity. The practical component of the study conducted can be recommended to municipal, regional and federal authorities, as well as the industrial enterprises, to support the adoption of the effective, environmentally sound management decisions that are consistent with the global concept of sustainable development.

  19. The Link between Age, Career Goals, and Adaptive Development for Work-Related Learning among Local Government Employees

    Science.gov (United States)

    Tones, Megan; Pillay, Hitendra; Kelly, Kathy

    2011-01-01

    More recently, lifespan development psychology models of adaptive development have been applied to the workforce to investigate ageing worker and lifespan issues. The current study uses the Learning and Development Survey (LDS) to investigate employee selection and engagement of learning and development goals and opportunities and constraints for…

  20. The Link between Age, Career Goals, and Adaptive Development for Work-Related Learning among Local Government Employees

    Science.gov (United States)

    Tones, Megan; Pillay, Hitendra; Kelly, Kathy

    2011-01-01

    More recently, lifespan development psychology models of adaptive development have been applied to the workforce to investigate ageing worker and lifespan issues. The current study uses the Learning and Development Survey (LDS) to investigate employee selection and engagement of learning and development goals and opportunities and constraints for…

  1. Adaptive Noise Reduction System

    Directory of Open Access Journals (Sweden)

    Ivana Ropuš

    2013-01-01

    Full Text Available Noise is an all-present environment pollutant, considered to be one of the greatest contemporary pollutants. World-wide, co-ordinated actions are conducted in order to develop systems which minimise the noise influence onto society.In this article we argue that novel approach to suppression of influence of noise is useful. Furthermore, we argue that the efficient approach is formulation of the efficient, broadly applicable, ubiquituous, adaptive noise-protection system. The approach combines the natural noise-protection form based on plants with the artificially formed coatings.Elements of the system are discussed, its formation and maintenance analysed and perspectives conjectured.

  2. Brain surgery in the bush: adapting techniques and technology to fit the developing world.

    Science.gov (United States)

    Vargas, Jan; Mayegga, Emanuel; Nuwas, Emmanuel; Ellegala, Dilantha B; Kucia, Elisa J; Nicholas, Joyce

    2013-11-01

    The critical shortage of surgical services in many areas of the world has profound effects on local communities. Approximately 11% of global disease burden can be attributed to causes that are surgically treatable. Efforts have been made to recruit professionals from developed nations to compensate for the lack of such expertise. However, this practice has created a cycle of dependency on foreign-trained physicians and the medical tools they bring. Recognition of this problem calls for adaptation of a novel problem-solving approach. This article describes techniques and technology available in east Africa that have been adapted to allow basic and emergency neurosurgery to be performed in the absence of complex medical infrastructure and equipment. Commonplace items found in the local environment can be used to emulate more sophisticated instruments, and community-specific engineering programs can be developed to provide locally produced appropriate technology that promotes independence from Western sources. The local economy benefits from much-needed stimulation when these tools are created locally, and this allows for readily available replacement and repair. More studies are under way to identify problems and implement interventions that are realistic and appropriate for these populations.

  3. Developing a new software package for PSF estimation and fitting of adaptive optics images

    Science.gov (United States)

    Schreiber, Laura; Diolaiti, Emiliano; Sollima, Antonio; Arcidiacono, Carmelo; Bellazzini, Michele; Ciliegi, Paolo; Falomo, Renato; Foppiani, Italo; Greggio, Laura; Lanzoni, Barbara; Lombini, Matteo; Montegriffo, Paolo; Dalessandro, Emanuele; Massari, Davide

    2012-07-01

    Adaptive Optics (AO) images are characterized by structured Point Spread Function (PSF), with sharp core and extended halo, and by significant variations across the field of view. In order to enable the extraction of high-precision quantitative information and improve the scientific exploitation of AO data, efforts in the PSF modeling and in the integration of suitable models in a code for image analysis are needed. We present the current status of a study on the modeling of AO PSFs based on observational data taken with present telescopes (VLT and LBT). The methods under development include parametric models and hybrid (i.e. analytical / numerical) models adapted to various types of PSFs that can show up in AO images. The specific features of AO data, such as the mainly radial variation of the PSF with respect to the guide star position in single-reference AO, are taken into account as much as possible. The final objective of this project is the development of a flexible software package, based on the Starfinder code (Diolaiati et Al 2000), specifically dedicated to the PSF estimation and to the astrometric and photometric analysis of AO images with complex and spatially variable PSF.

  4. Climate Variability, Andean Livelihood Strategies, Development and Adaptation in the Andean Region

    Science.gov (United States)

    Valdivia, C.; Quiroz, R.; Zorogastua, P.; Baigorrea, G.

    2002-05-01

    Development programs in the Andes have failed to recognize climate variability as an element that is crucial to the adoption of new alternatives. Dairy, potatoes, improved sheep, forages are all part of the history of development in this region. A combination of climate variability, changes in the economy, the political environment, and land tenure reform shape rural livelihoods and welfare. Diversification, linking to markets, and networking are some elements that contribute to the resilience of families in the Andes. Strategies change, are flexible, and may incorporate non-agricultural activities. While some farmers are able to improve their welfare through the life cycle, others become poorer. Climate variability increases the vulnerability of some groups; in other cases, because of diversification and assets, households build economic portfolios that are more resilient to the elements. The many projects provide insights into how in the long run households improve their environment, hinting at mechanisms to adapt to climate change. In order to understand changing composition of portfolios in future scenarios of spatial heterogeneous areas such as mountains (Andes), estimates of models predicting climate change at a global scale are not useful because their resolution. Therefore, downscaling tools are useful. Spatial heterogeneity is assessed through agroecozoning. Both production and the impact on some environmental indicators are simulated through process-based models, for the Ilave-Huenque watershed in Peru that help in discussing scenarios of adaptation.

  5. Development of an adaptive online fuzzy arbitrator for forecasting short-term natural gas usage

    Science.gov (United States)

    Lukas, Richard James, Jr.

    2001-07-01

    The focus of the work is on the development and utilization of a self-assembling Fuzzy logic controller for the purpose of improving short term natural gas load forecasts generated by artificial neural networks (ANN) and linear regression (LR) models. The approach is to form a matrix of dynamic post processors (DPP), composed of ARMAX models, which use load estimates generated by ANNs and LRs as inputs. The problem is to then determine the performance of each DPP under different operating conditions, and to generate a final load estimate using a Fuzzy logic controller. The contributions of this research are as follows. First, as part of a residuals analysis, prefiltering and nonlinear transforms are explored for the purpose of increasing the correlation of environmental input factors with gas load, while decreasing multicollinearity. This has the effect of reducing the covariance of model parameters and increasing forecast confidence. The result of this analysis will be used to develop ARMAX models to postfilter the ANN and LR forecast model estimates. The gas operating regions will be characterized by an adaptive clustering algorithm that will partition operating conditions into distinct patterns with unique consumption characteristics. Finally, an adaptive online Fuzzy controller identifies the characteristics of each DPP under different operating conditions, and generates a weighted average of the DPP estimators to produce the final gas load estimate.

  6. [The role of free radicals in the myocardial reperfusion injuries and in the development of endogenous adaptation].

    Science.gov (United States)

    Rőth, Erzsébet

    2015-11-22

    The reperfusion of acute ischaemic myocardium is essential for myocardial salvage, so-called "gold standard" therapy, however it can result in serious damage to the myocardium. Functional alterations occur, including depressed contractile function and decreased coronary flow as well as altered vascular reactivity. Over several decades it has been demonstrated that oxygen radical formation is greatly increased in the post-ischaemic heart and serves as a critical central mechanism of ischaemic-reperfusion injury. However it has been demonstrated that free radicals play an important role in the endogenous adaptation phenomenon of the heart, too. Ischaemic preconditioning is a cellular adaptive response of the heart to stress, which provides the most potent endogenous protection against reperfusion arrhytmias, stunning and infarction. Post-conditioning defined as brief periods of ischaemia and reperfusion during the very early minutes of reperfusion stimulates endogenous adaptation. Post-conditioning may also attenuate the damage to endothelial cells and cardiomyocytes from oxidants, cytokines, proteases and inflammatory cells.

  7. The Sustainable Development of Industry Clusters: Emergent Knowledge Networks and Socio Complex Adaptive Systems

    Directory of Open Access Journals (Sweden)

    Susu Nousala

    2009-10-01

    Full Text Available In a highly competitive global economy the development of sustainable, innovative responses from Industry is now vital. Many industries globally need to respond rather than react to current economic climate through sustainable (economically and environmentally development. The steel industry is a critical player in the urban landscape. Like many industries, small, medium enterprises (SMEs are vital players within the steel industry supply chain. The Australian SME steel housing sector (based in rural and regional areas are still developing systemic capabilities with the aim of realizing its full potential. The question of an effective sustainable industry is much larger than any one player. This paper aims to present a proposed methodological approach for sustainable cluster development based on previous industry wide investigations. Through the lens of scalability of a socio complex adaptive system, SME development becomes arguably the most significant player with regards to industry cluster development. By starting with SME development it's possible to build an understanding of a simultaneous two layered approach, "bottom up – top down" whilst including a very diversified group.

  8. The Sustainable Development of Industry Clusters: Emergent Knowledge Networks and Socio Complex Adaptive Systems

    Directory of Open Access Journals (Sweden)

    Susu Nousala

    2009-10-01

    Full Text Available In a highly competitive global economy the development of sustainable, innovative responses from Industry is now vital. Many industries globally need to respond rather than react to current economic climate through sustainable (economically and environmentally development. The steel industry is a critical player in the urban landscape. Like many industries, small, medium enterprises (SMEs are vital players within the steel industry supply chain. The Australian SME steel housing sector (based in rural and regional areas are still developing systemic capabilities with the aim of realizing its full potential. The question of an effective sustainable industry is much larger than any one player. This paper aims to present a proposed methodological approach for sustainable cluster development based on previous industry wide investigations. Through the lens of scalability of a socio complex adaptive system, SME development becomes arguably the most significant player with regards to industry cluster development. By starting with SME development it's possible to build an understanding of a simultaneous two layered approach, "bottom up – top down" whilst including a very diversified group.

  9. Development of adaptable and flexible treatment manuals for externalizing and internalizing disorders in children and adolescents

    Directory of Open Access Journals (Sweden)

    Bauermeister José J

    2006-01-01

    Full Text Available In this paper we describe the process used to develop treatment manuals for internalizing and externalizing disorders in children and adolescents. These manuals were developed to offer health care providers and others working in child mental health a flexible intervention that could be adapted to different countries and localities based on: 1 the amount of health care and school resources that are available; 2 the nature and severity of the types of problems children have; and 3 the preferences and cultural factors that are important within these communities. We also discuss the experiences and cultural issues faced by sites in Egypt, Lebanon, Israel, and Brazil who volunteered to implement the manualized treatment programs. The feedback received from these sites indicates that the manuals can be implemented to help children with internalizing and externalizing problems.

  10. Developing services for climate impact and adaptation baseline information and methodologies for the Andes

    Science.gov (United States)

    Huggel, C.

    2012-04-01

    Impacts of climate change are observed and projected across a range of ecosystems and economic sectors, and mountain regions thereby rank among the hotspots of climate change. The Andes are considered particularly vulnerable to climate change, not only due to fragile ecosystems but also due to the high vulnerability of the population. Natural resources such as water systems play a critical role and are observed and projected to be seriously affected. Adaptation to climate change impacts is therefore crucial to contain the negative effects on the population. Adaptation projects require information on the climate and affected socio-environmental systems. There is, however, generally a lack of methodological guidelines how to generate the necessary scientific information and how to communicate to implementing governmental and non-governmental institutions. This is particularly important in view of the international funds for adaptation such as the Green Climate Fund established and set into process at the UNFCCC Conferences of the Parties in Cancun 2010 and Durban 2011. To facilitate this process international and regional organizations (World Bank and Andean Community) and a consortium of research institutions have joined forces to develop and define comprehensive methodologies for baseline and climate change impact assessments for the Andes, with an application potential to other mountain regions (AndesPlus project). Considered are the climatological baseline of a region, and the assessment of trends based on ground meteorological stations, reanalysis data, and satellite information. A challenge is the scarcity of climate information in the Andes, and the complex climatology of the mountain terrain. A climate data platform has been developed for the southern Peruvian Andes and is a key element for climate data service and exchange. Water resources are among the key livelihood components for the Andean population, and local and national economy, in particular for

  11. Development of adaptive pneumatic tourniquet systems based on minimal inflation pressure for upper limb surgeries.

    Science.gov (United States)

    Liu, Hong-yun; Guo, Jun-yan; Zhang, Zheng-bo; Li, Kai-yuan; Wang, Wei-dong

    2013-09-23

    Pneumatic tourniquets are medical devices that occlude blood flow to distal part of extremities and are commonly used in upper limb surgeries to provide a dry, clean and bloodless field. To decrease pressure-related injuries and potential risk of complications subjected to the high inflation pressure of pneumatic tourniquet, minimal inflation pressures are recommended. A new occlusion pressure mathematical model for the upper limb was established based on the correlation analysis between several possible influencing parameters and the minimal pneumatic tourniquet pressure at which the peripheral pulse disappeared was recorded using a digital plethysmograph. A prototype of an adaptive pneumatic tourniquet which automatically varies the pressure in the tourniquet cuff according to the above prediction model was developed for the upper limb which used the lowest possible inflation pressure to achieve occlusion. The prototype comprises a blood pressure monitoring module, an inflatable tourniquet cuff, and a pressure relief mechanism to maintain an optimal cuff inflation pressure. Simulation experiments were conducted to verify the function and stability of the designed adaptive pneumatic tourniquet and clinical experiments using volunteers were undertaken to evaluate the performance of the prototype design in achieving adequate haemostasis in the upper limb. Results demonstrated that the mean arterial occlusion pressure was 152.3 ± 16.7 mmHg, obviously below the 250 to 300 mmHg previously recommended (J Bone Joint Surg Br 68:625-628, 1986 and Arthroscopy 11:307-311, 1995). In conclusion, this adaptive method and apparatus which can provide minimal inflation pressure may be a clinically practical alternative for upper limb surgery performed with pneumatic tourniquets.

  12. Spanish version of the Talent Development Environment Questionnaire for sport: Cultural adaptation and initial validation.

    Science.gov (United States)

    Brazo-Sayavera, Javier; Olivares, Pedro R; Andronikos, Georgios; Martindale, Russell J J

    2017-01-01

    This study aimed to translate the Talent Development Environment Questionnaire into Spanish and provide an initial validation. A recommended methodology for translation and cultural adaptation of questionnaires was applied. Once this had been completed, three hundred and thirty-two young athletes completed the Talent Development Environment Questionnaire. The results revealed that the five factor solution Talent Development Environment Questionnaire was confirmed. With the exclusion of one item due to low factor loading, the Talent Development Environment Questionnaire-5 had robust statistical support for its factor structure (χ2 (df = 305) = 499.64, p<0.01, CFI = 0.90, RMSEA = 0.045, SRMR = 0.055). It also demonstrated adequate convergent and discriminant validity. While the internal reliability was lower than in previous studies, it revealed acceptable levels. Specifically the overall 27 item Talent Development Environment Questionnaire-5 had a Cronbach α score of .877, and the reliability scores for individual factors 1-5 were .622; .761; .658; .605; .602 respectively. As such, it is recommended that the Spanish Talent Development Environment Questionnaire-5 can be used with confidence in Spain in both applied and research settings.

  13. Adaptation of the quality by design concept in early pharmaceutical development of an intranasal nanosized formulation.

    Science.gov (United States)

    Pallagi, Edina; Ambrus, Rita; Szabó-Révész, Piroska; Csóka, Ildikó

    2015-08-01

    Regulatory science based pharmaceutical development and product manufacturing is highly recommended by the authorities nowadays. The aim of this study was to adapt regulatory science even in the nano-pharmaceutical early development. Authors applied the quality by design (QbD) concept in the early development phase of nano-systems, where the illustration material was meloxicam. The meloxicam nanoparticles produced by co-grinding method for nasal administration were studied according to the QbD policy and the QbD based risk assessment (RA) was performed. The steps were implemented according to the relevant regulatory guidelines (quality target product profile (QTPP) determination, selection of critical quality attributes (CQAs) and critical process parameters (CPPs)) and a special software (Lean QbD Software(®)) was used for the RA, which represents a novelty in this field. The RA was able to predict and identify theoretically the factors (e.g. sample composition, production method parameters, etc.) which have the highest impact on the desired meloxicam-product quality. The results of the practical research justified the theoretical prediction. This method can improve pharmaceutical nano-developments by achieving shorter development time, lower cost, saving human resource efforts and more effective target-orientation. It makes possible focusing the resources on the selected parameters and area during the practical product development.

  14. STUDY CONSIDERING THE ENVIRONMENTAL PROTECTION AND LIFE QUALITY IN ROMANIA IN THE CONTEXT OF SUSTAINABLE DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Gheorghe Sebastian SÂRB

    2013-10-01

    Full Text Available The environmental protection represents an important subject in international debates, being accentuated by the alert rhythm of economic development and the higher demands of the current consumer generations. In general, it can be claimed that the most developed countries are producing the largest quantities of waste and pollutants and are consuming large quantities of energy and natural resources. The impact these countries have upon the natural environment is strong and destructive. Therefore, it can be remarked that the industrialization level is inversely proportional with the environmental state, which is getting worse by the year: reduced timbered areas, agricultural soil degradation, a thinner ozone layer, numerous extinct plant and animal species, accentuated greenhouse effect, etc. Affecting the natural environment has severe repercussions upon the quality of life, manifesting itself through water, soil and atmospheric pollution. These are the reasons why the authors of this paper are analysing, in the present study, the problems concerning the environmental protection and life quality.

  15. An Analysis of The Early Development and Protection of the Colorado River

    Institute of Scientific and Technical Information of China (English)

    Zhao Qian

    2009-01-01

    This thesis attempts an environmental analysis of the Colorado River in Southwest America.and examines the early issues of economic development and environmental protection on the Colorado River Basin from a historical perspective.The thesis first provides a brief description of the geography of the Colorado River,paying special attention to the early exploration of the Colorado River by Native Americans and later European colonizers as well as their different attitudes toward nature.Then the thesis looks at the forces of economic development and nature preservation in the progressive era against the arid setting of the Southwest.In the conclusion,the author demonstrates the importance and necessity of the environmental protection of the Colorado River in the beginning period of the America West.

  16. Development of Protective Coatings for Co-Sequestration Processes and Pipelines

    Energy Technology Data Exchange (ETDEWEB)

    Bierwagen, Gordon; Huang, Yaping

    2011-11-30

    The program, entitled Development of Protective Coatings for Co-Sequestration Processes and Pipelines, examined the sensitivity of existing coating systems to supercritical carbon dioxide (SCCO2) exposure and developed new coating system to protect pipelines from their corrosion under SCCO2 exposure. A literature review was also conducted regarding pipeline corrosion sensors to monitor pipes used in handling co-sequestration fluids. Research was to ensure safety and reliability for a pipeline involving transport of SCCO2 from the power plant to the sequestration site to mitigate the greenhouse gas effect. Results showed that one commercial coating and one designed formulation can both be supplied as potential candidates for internal pipeline coating to transport SCCO2.

  17. A confirmatory factor analysis of the Resilience Scale adapted to chronic pain (RS-18): new empirical evidence of the protective role of resilience on pain adjustment.

    Science.gov (United States)

    Ruiz-Párraga, Gema T; López-Martínez, Alicia E; Esteve, Rosa; Ramírez-Maestre, Carmen; Wagnild, Gail

    2015-05-01

    Recent attention has focused on resilience as an important process in the experience and management of chronic pain. In this context, resilience is considered as a psychological factor that promotes adaptive responses to pain and pain-related life adversities. Current research suggests that it is a relevant variable in the prediction of pain adjustment among chronic pain patients. Recently, it was adapted the Resilience Scale to patients suffering chronic musculoskeletal pain (RS-18). The aims of this study were to confirm the internal structure of the RS-18 and to present new empirical evidence regarding its validity. A sample of 592 patients with chronic musculoskeletal back pain completed a battery of instruments to assess resilience, anxiety sensitivity, catastrophizing, fear-avoidance beliefs, hypervigilance, pain acceptance, and pain adjustment variables (pain intensity, emotional distress, functional impairment, and daily functioning). Confirmatory factor analysis supported the validity of the RS-18 and a single-factor solution. A series of moderated multiple regression analysis showed that resilience is a relevant psychological variable that not only independently predicts better pain adjustment, but also moderates the relationships between several psychological pain-related variables and pain adjustment variables. These findings give empirical support to the consideration of resilience as a protective variable in chronic pain adjustment and highlight the consideration that improving resilient behaviour could be an important target for the treatment of pain patients.

  18. Diabetic beta-cells can achieve self-protection against oxidative stress through an adaptive up-regulation of their antioxidant defenses.

    Directory of Open Access Journals (Sweden)

    Grégory Lacraz

    Full Text Available BACKGROUND: Oxidative stress (OS, through excessive and/or chronic reactive oxygen species (ROS, is a mediator of diabetes-related damages in various tissues including pancreatic beta-cells. Here, we have evaluated islet OS status and beta-cell response to ROS using the GK/Par rat as a model of type 2 diabetes. METHODOLOGY/PRINCIPAL FINDINGS: Localization of OS markers was performed on whole pancreases. Using islets isolated from 7-day-old or 2.5-month-old male GK/Par and Wistar control rats, 1 gene expression was analyzed by qRT-PCR; 2 insulin secretion rate was measured; 3 ROS accumulation and mitochondrial polarization were assessed by fluorescence methods; 4 antioxidant contents were quantified by HPLC. After diabetes onset, OS markers targeted mostly peri-islet vascular and inflammatory areas, and not islet cells. GK/Par islets revealed in fact protected against OS, because they maintained basal ROS accumulation similar or even lower than Wistar islets. Remarkably, GK/Par insulin secretion also exhibited strong resistance to the toxic effect of exogenous H(2O(2 or endogenous ROS exposure. Such adaptation was associated to both high glutathione content and overexpression (mRNA and/or protein levels of a large set of genes encoding antioxidant proteins as well as UCP2. Finally, we showed that such a phenotype was not innate but spontaneously acquired after diabetes onset, as the result of an adaptive response to the diabetic environment. CONCLUSIONS: The GK/Par model illustrates the effectiveness of adaptive response to OS by beta-cells to achieve self-tolerance. It remains to be determined to what extend such islet antioxidant defenses upregulation might contribute to GK/Par beta-cell secretory dysfunction.

  19. Broken forest: Applying the integrated conservation and development paradigm to Madagascar's protected areas

    Energy Technology Data Exchange (ETDEWEB)

    Barbour, R.; Rabezandria, R.; Daviesson, R.; Guyton, W.; Rakotobe.

    1992-06-01

    The destruction of Madagascar's primary forests through agricultural clearing poses a grave threat to the island's biodiversity. The report assesses the potential of the planned Sustainable and Viable Environmental Management (SAVEM) Project to minimize this threat by implementing Integrated Conservation Development Projects (ICDP's), which link resource conservation to income-generating activities, in the peripheral zones of Madagascar's protected areas.

  20. PROTECTIVE GUARANTEES AND OTHER REQUIREMENTS TO STRENGTHEN DEVELOPMENT OF THE BANK-CUSTOMER CONTRACTUAL RELATIONSHIP

    Directory of Open Access Journals (Sweden)

    MEDAR LUCIAN-ION

    2013-02-01

    Full Text Available Contractual relationships between individuals and credit institutions are increasingly lower in the sphere of lendingactivity. Implementation of the new Civil Procedure Code starting with February, 2013, strengthened even moreconsumer protection which has disturbed some commercial banks. Trust between banks and customers is an essentialrequirement for developing banking businesses. As a result of occurrence of new legislation is necessary to know themain elements that strengthen bank-client contractual relationship.

  1. Research and development to protect soldiers from landmines and improvised explosive devices

    CSIR Research Space (South Africa)

    Ahmed, R

    2015-10-01

    Full Text Available stream_source_info Ahmed_2015.pdf.txt stream_content_type text/plain stream_size 3528 Content-Encoding UTF-8 stream_name Ahmed_2015.pdf.txt Content-Type text/plain; charset=UTF-8 Research and Development to Protect... medium Explosively Formed Projectile (EFP) IED threat Case Study Threat Characterisation: EFPs are usually characterised in terms of the projectile formed: – Mass – Speed kinetic energy over distance required...

  2. Relationship between Tourism Development and Ecological Protection in Songshan National Nature Reserve,Beijing City

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Nowadays Songshan National Nature Reserve attracts a rapidly increasing number of tourists. However, the development of a tourist economy and the further exploitation of the natural landscape threaten the ecology and management of the reserve. Therefore, defining the relationship between ecological tourism and ecological protection can provide a framework for the management and exploitation of the reserve. Based on the analysis of current situation and questions of the reserve, this paper probes into the re...

  3. Domestic violence from the perspective of the development and protection of children

    OpenAIRE

    Irena Sobotková

    2016-01-01

    The article deals with a socially relevant and actual issue of domestic violence with respect to the development and protection of children. First, it describes the concept of domestic violence, particularly intimate partner violence, and brings some numerical data. In spite of the fact that the reported numbers are different, each situation when a child is exposed to the domestic violence is very unfavorable or even traumatic for him. The immediate effects are feelings of fear, anxiety, conf...

  4. Landscape suitability evaluation as a tool for development and protection of valuable rural areas

    Directory of Open Access Journals (Sweden)

    Dora Tomić

    2015-12-01

    Full Text Available This research studied application possibilities of landscape suitability evaluation as a methodological approach within landscape planning. It was presented in the case study of the wider area of Krka River through analysis of three Mediterranean agricultural crops. Results indicated (1 the efficacy of the procedure for obtaining optimised spatial potential for development as well as protection of valuable rural areas and (2 the possibility to include new methods into current planning regulations.

  5. Development of a climate change adaptation plan : guide for Quebec municipalities; Elaborer un plan d'adaptation aux changements climatiques : guide destine au milieu municipal quebecois

    Energy Technology Data Exchange (ETDEWEB)

    Larrivee, C. (comp.) [Ouranos, Montreal, PQ (Canada); Moffet, V.; Robitaille, P. [Quebec Ministere du Developpement durable, de l' Environnement et des Parcs, Quebec, PQ (Canada); Blais, P.; Marceau, M.; Dupuis, C. [Quebec Ministere des Affaires municipales, des Regions et de l' Occupation du territoire, Quebec, PQ (Canada); Desjarlais, C.; Bourque, A. [Ouranos, Montreal, PQ (Canada)

    2010-01-15

    This article presented Quebec's strategies for developing a climate change action plan in response to increasing greenhouse gas emissions and to minimize environmental impacts. In addition to a rise in average temperature, the increase of greenhouse gas emissions will affect many other climate variables such as precipitation and wind. The impacts may vary widely between regions and municipalities, but all will have to deal with the changes in the natural environment, populations and socio-economic activities within municipalities. The adaptation plan must also consider non-climate factors such as infrastructure and socio demographic characteristics of a municipality in order to determine risks by order of priority and to develop an action plan if needed. In addition to educating the population, the strategies involve obtaining a clear mandate from each municipal council to form a multidisciplinary group, name a coordinator who will have a global vision of the plan and propose a deadline. Implementing an adaptation plan involves the following 5 steps: (1) evaluating the present impact of the climate, (2) defining the potential impacts of climate changes and analyzing its vulnerabilities, (3) recognizing the risks, (4) prioritizing options to manage the recognized risks, and (5) developing and implementing an adaptation plan. This plan will determine the criteria to measure the performance, evaluate and amend its outcome periodically if necessary. 19 refs., 9 tabs., 12 figs.

  6. (Unsupported Current Tourism Development in UNESCO Protected Site: The Case of Old City of Dubrovnik

    Directory of Open Access Journals (Sweden)

    Ivana Pavlić

    2017-03-01

    Full Text Available The main purpose of this paper is to explore and determine perceptions of residents living in the United Nations Educational, Scientific and Cultural Organization (UNESCO protected site Old City of Dubrovnik (OCD towards tourism development. Uncontrolled tourism expansion has impact on local residents’ life and on their (unsupport for specific form of tourism development. Comprehension of residents’ perceptions is crucial for realization of adequate tourism development and for mutual satisfaction of tourism demand and supply. Therefore, the aim is to test the model of residents’ perceptions of economic, socio-cultural and environmental impacts of tourism on their (unsupport for specific form of tourism development. To realize the purpose of this research, Cronbach alpha, explorative (EFC and confirmatory (CFA factor analysis, and structural equation modeling (SEM were applied. The findings indicate that there is a direct relationship between residents who perceive positive and negative economic, socio-cultural and environmental impacts of tourism and their (unsupport for tourism development. This paper points out the role and significance of the permanent residents’ perceptions research concerning the issues that are related to the quality tourism development due to the high interaction between local residents, tourists and local tourism development especially in the areas under the protection of UNESCO.

  7. Evaluation of the efficiency of development of specially protected natural areas in the Republic of Komi

    Directory of Open Access Journals (Sweden)

    Tat’yana Vyacheslavovna Tikhonova

    2015-03-01

    Full Text Available The article presents an algorithm for the management of specially protected natural areas in the region. This algorithm consists of the following procedures: assumption of the obligation to preserve biodiversity; planning and implementation of activities to preserve natural complexes; evaluation, analysis of results and development of recommendations to improve management. According to this algorithm the procedures were tested on model objects – specially protected natural territories of federal and regional importance. In the course of implementation of these activities the sources of funding of specially protected model objects were identified: the funds of budgets of all levels; grants and charitable contributions; funds received from the provision of recreation and tourism services. The financial strategies of development were provided, and the business plans were analysed for seven natural reserves. The results of a sociological survey concerning the effectiveness of implementation of business plans show that positive effects from the existence of protected areas are much more pronounced than the limitations experienced by local residents. This refers to the opportunities and forms of cooperation and contribution to socio-economic development in the region. The activities for the organization of recreation for residents in the region are proposed. Recreation at the weekend, the costs of which amount to two thousand rubles/person, is most interesting to the region’s residents, especially to urban residents. This type of recreation can organize a flow of 200 thousand people per year, if the necessary range of services, especially children’s leisure, is provided. Leisure tourism, on the contrary, requires the maximum reduction of cost (five thousand rubles/ person for the route, and the provision of minimum number of services; the annual flow of this category of tourists may reach 40 thousand people. Establishment of conventional natural

  8. Development of Adaptive Acoustic Impedance Control Technologies of Acoustic Duct Liner

    Directory of Open Access Journals (Sweden)

    Hiroshi Kobayashi

    2011-01-01

    Full Text Available This paper describes the development of adaptive acoustic impedance control (AAC technologies to achieve a larger fan noise reduction, by adaptively adjusting reactance and resistance of the acoustic liner impedance. For the actual proof of the AAC technology III performance, the advanced fan noise absorption control duct liner II was made on trial basis, with the simple control system and the plain device. And, then, the duct liner II was examined for the AAC technology I, II, and III models, using the high speed fan test facility. The test results made clear that the duct liner II of the AAC technology III model could achieve the fan noise reduction higher than O.A. SPL 10 dB (A at the maximum fan speed 6000 rpm, containing the reduction of fundamental BPF tone of 18 dB and 2nd BPF tone of 10 dB in response to the fan peed change from 3000 to 6000 rpm.

  9. Developing and Evaluating an Adaptive Business English Self-Learning System for EFL Vocabulary Learning

    Directory of Open Access Journals (Sweden)

    Yen-Hui Wang

    2014-01-01

    Full Text Available This paper developed an adaptive Business English self-learning system for EFL vocabulary learning. The components of word reoccurrence and learner engagement have been built into the system where the amount of unknown word reexposure in various customized texts increases and vocabulary enhancement tasks are added to promote learner engagement with wanted words. To evaluate the system effectiveness on EFL vocabulary learning, the experimental group read system-screened texts with immediate and repeated contacts with individuals’ unknown words and performed vocabulary tasks specific to those unknown words, while the control group read online texts without unknown word reoccurrence and vocabulary practice. After one semester, these two groups were measured by one online vocabulary test, and an online user satisfaction investigation was also administered to the experimental group. The study found that the experimental group reading customized texts to reexpose to previously encountered unknown words in different texts along with doing individualized vocabulary exercises performed significantly better in EFL vocabulary learning than the other group. It was also found that the system was appealing for the learners to show positive attitudes toward the use of the system. The study demonstrated that the constructed adaptive Business English self-learning system could effectively promote vocabulary growth.

  10. Early and late rate of force development: differential adaptive responses to resistance training?

    Science.gov (United States)

    Andersen, L L; Andersen, J L; Zebis, M K; Aagaard, P

    2010-02-01

    The objective of this study is to investigate the potentially opposing influence of qualitative and quantitative muscular adaptations in response to high-intensity resistance training on contractile rate of force development (RFD) in the early (200 ms) of rising muscle force. Fifteen healthy young males participated in a 14-week resistance training intervention for the lower body and 10 matched subjects participated as controls. Maximal muscle strength (MVC) and RFD were measured during maximal voluntary isometric contraction of the quadriceps femoris muscle. Muscle biopsies were obtained from the vastus lateralis. The main findings were that RFD in the late phase of rising muscle force increased in response to resistance training whereas early RFD remained unchanged and early relative RFD (i.e., RFD/MVC) decreased. Quantitatively, muscle fiber cross-sectional area and MVC increased whereas, qualitatively, the relative proportion of type IIX muscle fibers decreased. Multiple regression analysis showed that while increased MVC positively influenced both early and late RFD, decreased-type IIX negatively influenced early RFD only. In conclusion, early and late RFD responded differently to high-intensity resistance training due to differential influences of qualitative and quantitative muscular adaptations on early and later phases of rising muscle force.

  11. Adaptive Cell Segmentation and Tracking for Volumetric Confocal Microscopy Images of a Developing Plant Meristem

    Institute of Scientific and Technical Information of China (English)

    Min Liu; Anirban Chakraborty; Damanpreet Singh; Ram Kishor Yadav; Gopi Meenakshisundaram; G. Venugopala Reddy; Amit Roy-Chowdhury

    2011-01-01

    Automated segmentation and tracking of cells in actively developing tissues can provide high-throughput and quantitative spatiotemporal measurements of a range of cell behaviors; cell expansion and cell-division kinetics leading to a better understanding of the underlying dynamics of morphogenesis.Here,we have studied the problem of constructing cell lineages in time-lapse volumetric image stacks obtained using Confocal Laser Scanning Microscopy (CLSM).The novel contribution of the work lies in its ability to segment and track cells in densely packed tissue,the shoot apical meristem (SAM),through the use of a close-loop,adaptive segmentation,and tracking approach.The tracking output acts as an indicator of the quality of segmentation and,in turn,the segmentation can be improved to obtain better tracking results.We construct an optimization function that minimizes the segmentation error,which is,in turn,estimated from the tracking results.This adaptive approach significantly improves both tracking and segmentation when compared to an open loop framework in which segmentation and tracking modules operate separately.

  12. The regional governance of climate adaptation: a framework for developing legitimate, effective, and resilient governance arrangements

    NARCIS (Netherlands)

    Termeer, C.J.A.M.; Dewulf, A.; Rijswick, H.F.M.W.; Buuren, van A.; Huitema, D.; Meijerink, S.; Rayner, T.; Wiering, M.

    2011-01-01

    Adaptation to climate change raises important governance issues. Notwithstanding the increasing attention on climate adaptation at the global and European level, the variety of local conditions and climate impacts points towards a prime role for regional actors in climate change adaptation. They fac

  13. The Development of Adaptive Skills in Young People with Down Syndrome

    Science.gov (United States)

    Van Duijn, G.; Dijkxhoorn, Y.; Scholte, E. M.; Van Berckelaer-Onnes, I. A.

    2010-01-01

    Background: To help children with Down syndrome reach optimum levels of adaptive behaviour, caretakers need to know how and to what extent children with Down syndrome acquire adaptive skills. Method: The adaptive levels of motor, daily living, communicative and social behavioural skills were determined in a group of 984 Dutch children with Down…

  14. The Development of Adaptive Skills in Young People with Down Syndrome

    Science.gov (United States)

    Van Duijn, G.; Dijkxhoorn, Y.; Scholte, E. M.; Van Berckelaer-Onnes, I. A.

    2010-01-01

    Background: To help children with Down syndrome reach optimum levels of adaptive behaviour, caretakers need to know how and to what extent children with Down syndrome acquire adaptive skills. Method: The adaptive levels of motor, daily living, communicative and social behavioural skills were determined in a group of 984 Dutch children with Down…

  15. Low-dose energetic protons induce adaptive and bystander effects that protect human cells against DNA damage caused by a subsequent exposure to energetic iron ions.

    Science.gov (United States)

    Buonanno, Manuela; De Toledo, Sonia M; Howell, Roger W; Azzam, Edouard I

    2015-05-01

    During interplanetary missions, astronauts are exposed to mixed types of ionizing radiation. The low 'flux' of the high atomic number and high energy (HZE) radiations relative to the higher 'flux' of low linear energy transfer (LET) protons makes it highly probable that for any given cell in the body, proton events will precede any HZE event. Whereas progress has been made in our understanding of the biological effects of low-LET protons and high-LET HZE particles, the interplay between the biochemical processes modulated by these radiations is unclear. Here we show that exposure of normal human fibroblasts to a low mean absorbed dose of 20 cGy of 0.05 or 1-GeV protons (LET ∼ 1.25 or 0.2 keV/μm, respectively) protects the irradiated cells (P cellular traversal by radiation with those due to bystander effects in cell populations exposed to mixed radiation fields. They show that protective adaptive responses can spread from cells targeted by low-LET space radiation to bystander cells in their vicinity. The findings are relevant to understanding the health hazards of space travel. © The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

  16. Barriers to reducing climate enhanced disaster risks in Least Developed Country-Small Islands through anticipatory adaptation

    Directory of Open Access Journals (Sweden)

    Natasha Kuruppu

    2015-03-01

    Full Text Available Small Island Developing States (SIDS classified as Least Developed Countries (LDCs are particularly vulnerable to the projected impacts of climate change. Given their particular vulnerabilities, climate adaptation investments are being made through both national and international efforts to build the capacity of various sectors and communities to reduce climate risks and associated disasters. Despite these efforts, reducing climate risks is not free of various challenges and barriers. This paper aims to synthesise a set of critical socio-economic barriers present at various spatial scales that are specific to Least Developed Country SIDS. It also aims to identify the processes that give rise to these barriers. Drawing on theories from natural hazards, a systematic literature review method was adopted to identify and organise the set of barriers by focussing on both academic papers and grey literature. The data revealed a notable lack of studies on adaptation within African and Caribbean LDC-SIDS. In general, there was a paucity of academic as well as grey literature being produced by authors from LDC-SIDS to challenge existing discourses related to adaptation barriers. The most common barriers identified included those related to governance, technical, cognitive and cultural. Three key findings can be drawn from this study in relation to formal adaptation initiatives. Firstly, the lack of focus on the adaptive capacity needs of Local Government or Island Councils and communities was a key barrier to ensure success of adaptation interventions. Secondly, international adaptation funding modalities did little to address root causes of vulnerability or support system transformations. These funds were geared at supporting sectoral level adaptation initiatives for vulnerable natural resource sectors such as water, biodiversity and coastal zones. Thirdly, there is a need to recognise the significance of cultural knowledge and practices in shaping

  17. Barriers to reducing climate enhanced disaster risks in Least Developed Country-Small Islands through anticipatory adaptation

    Science.gov (United States)

    Kuruppu, N.; Willie, R.

    2015-12-01

    Small Island Developing States (SIDS) classified as Least Developed Countries (LDCs) are particularly vulnerable to the projected impacts of climate change. Given their particular vulnerabilities, climate adaptation investments are being made through both national and international efforts to build the capacity of various sectors and communities to reduce climate risks and associated disasters. Despite these efforts, reducing climate risks is not free of various challenges and barriers. This paper aims to synthesise a set of critical socio-economic barriers present at various spatial scales that are specific to Least Developed Country SIDS. It also aims to identify the processes that give rise to these barriers. Drawing on theories from natural hazards, a systematic literature review method was adopted to identify and organise the set of barriers by focussing both on academic papers and grey literature. The data revealed a notable lack of studies on adaptation within African and Caribbean LDC-SIDS. In general, there was a paucity of academic as well as grey literature being produced by authors from LDC-SIDS to challenge existing discourses related to adaptation barriers. The most common barriers identified included those related to governance, technical, cognitive and cultural. Three key findings can be drawn from this study in relation to formal adaptation initiatives. Firstly, the lack of focus on the adaptive capacity needs of Local Government or Island Councils and communities was a key barrier to ensuring success of adaptation interventions. Secondly, international adaptation funding modalities did little to address root causes of vulnerability or support system transformations. These funds were geared at supporting sectoral level adaptation initiatives for vulnerable natural resource sectors such as water, biodiversity and coastal zones. Thirdly, there is a need to recognise the significance of cultural knowledge and practices in shaping adaptive choices of

  18. Adapting the Assessing British Sign Language Development: Receptive Skills Test into American sign language.

    Science.gov (United States)

    Enns, Charlotte J; Herman, Rosalind C

    2011-01-01

    Signed languages continue to be a key element of deaf education programs that incorporate a bilingual approach to teaching and learning. In order to monitor the success of bilingual deaf education programs, and in particular to monitor the progress of children acquiring signed language, it is essential to develop an assessment tool of signed language skills. Although researchers have developed some checklists and experimental tests related to American Sign Language (ASL) assessment, at this time a standardized measure of ASL does not exist. There have been tests developed in other signed languages, for example, British Sign Language, that can serve as models in this area. The purpose of this study was to adapt the Assessing British Sign Language Development: Receptive Skills Test for use in ASL in order to begin the process of developing a standardized measure of ASL skills. The results suggest that collaboration between researchers in different signed languages can provide a valuable contribution toward filling the gap in the area of signed language assessment.

  19. An Adaptive Framework for Selecting Environmental Monitoring Protocols to Support Ocean Renewable Energy Development

    Directory of Open Access Journals (Sweden)

    Emily J. Shumchenia

    2012-01-01

    Full Text Available Offshore renewable energy developments (OREDs are projected to become common in the United States over the next two decades. There are both a need and an opportunity to guide efforts to identify and track impacts to the marine ecosystem resulting from these installations. A monitoring framework and standardized protocols that can be applied to multiple types of ORED would streamline scientific study, management, and permitting at these sites. We propose an adaptive and reactive framework based on indicators of the likely changes to the marine ecosystem due to ORED. We developed decision trees to identify suites of impacts at two scales (demonstration and commercial depending on energy (wind, tidal, and wave, structure (e.g., turbine, and foundation type (e.g., monopile. Impacts were categorized by ecosystem component (benthic habitat and resources, fish and fisheries, avian species, marine mammals, and sea turtles and monitoring objectives were developed for each. We present a case study at a commercial-scale wind farm and develop a monitoring plan for this development that addresses both local and national environmental concerns. In addition, framework has provided a starting point for identifying global research needs and objectives for understanding of the potential effects of ORED on the marine environment.

  20. Development, malaria and adaptation to climate change: a case study from India.

    Science.gov (United States)

    Garg, Amit; Dhiman, R C; Bhattacharya, Sumana; Shukla, P R

    2009-05-01

    India has reasons to be concerned about climate change. Over 650 million people depend on climate-sensitive sectors, such as rain-fed agriculture and forestry, for livelihood and over 973 million people are exposed to vector borne malarial parasites. Projection of climatic factors indicates a wider exposure to malaria for the Indian population in the future. If precautionary measures are not taken and development processes are not managed properly some developmental activities, such as hydro-electric dams and irrigation canal systems, may also exacerbate breeding grounds for malaria. This article integrates climate change and developmental variables in articulating a framework for integrated impact assessment and adaptation responses, with malaria incidence in India as a case study. The climate change variables include temperature, rainfall, humidity, extreme events, and other secondary variables. Development variables are income levels, institutional mechanisms to implement preventive measures, infrastructure development that could promote malarial breeding grounds, and other policies. The case study indicates that sustainable development variables may sometimes reduce the adverse impacts on the system due to climate change alone, while it may sometimes also exacerbate these impacts if the development variables are not managed well and therefore they produce a negative impact on the system. The study concludes that well crafted and well managed developmental policies could result in enhanced resilience of communities and systems, and lower health impacts due to climate change.

  1. Development, Malaria and Adaptation to Climate Change: A Case Study from India

    Science.gov (United States)

    Garg, Amit; Dhiman, R. C.; Bhattacharya, Sumana; Shukla, P. R.

    2009-05-01

    India has reasons to be concerned about climate change. Over 650 million people depend on climate-sensitive sectors, such as rain-fed agriculture and forestry, for livelihood and over 973 million people are exposed to vector borne malarial parasites. Projection of climatic factors indicates a wider exposure to malaria for the Indian population in the future. If precautionary measures are not taken and development processes are not managed properly some developmental activities, such as hydro-electric dams and irrigation canal systems, may also exacerbate breeding grounds for malaria. This article integrates climate change and developmental variables in articulating a framework for integrated impact assessment and adaptation responses, with malaria incidence in India as a case study. The climate change variables include temperature, rainfall, humidity, extreme events, and other secondary variables. Development variables are income levels, institutional mechanisms to implement preventive measures, infrastructure development that could promote malarial breeding grounds, and other policies. The case study indicates that sustainable development variables may sometimes reduce the adverse impacts on the system due to climate change alone, while it may sometimes also exacerbate these impacts if the development variables are not managed well and therefore they produce a negative impact on the system. The study concludes that well crafted and well managed developmental policies could result in enhanced resilience of communities and systems, and lower health impacts due to climate change.

  2. Elevated Glucose Oxidation, Reduced Insulin Secretion, and a Fatty Heart May Be Protective Adaptions in Ischemic CAD.

    Science.gov (United States)

    Hannukainen, J C; Lautamäki, R; Mari, A; Pärkkä, J P; Bucci, M; Guzzardi, M A; Kajander, S; Tuokkola, T; Knuuti, J; Iozzo, P

    2016-07-01

    Insulin resistance, β-cell dysfunction, and ectopic fat deposition have been implicated in the pathogenesis of coronary artery disease (CAD) and type 2 diabetes, which is common in CAD patients. We investigated whether CAD is an independent predictor of these metabolic abnormalities and whether this interaction is influenced by superimposed myocardial ischemia. We studied CAD patients with (n = 8) and without (n = 14) myocardial ischemia and eight non-CAD controls. Insulin sensitivity and secretion and substrate oxidation were measured during fasting and oral glucose tolerance testing. We used magnetic resonance imaging/spectroscopy, positron emission and computerized tomography to characterize CAD, cardiac function, pericardial and abdominal adipose tissue, and myocardial, liver, and pancreatic triglyceride contents. Ischemic CAD was characterized by elevated oxidative glucose metabolism and a proportional decline in β-cell insulin secretion and reduction in lipid oxidation. Cardiac function was preserved in CAD groups, whereas cardiac fat depots were elevated in ischemic CAD compared to non-CAD subjects. Liver and pancreatic fat contents were similar in all groups and related with surrounding adipose masses or systemic insulin sensitivity. In ischemic CAD patients, glucose oxidation is enhanced and correlates inversely with insulin secretion. This can be seen as a mechanism to prevent glucose lowering because glucose is required in oxygen-deprived tissues. On the other hand, the accumulation of cardiac triglycerides may be a physiological adaptation to the limited fatty acid oxidative capacity. Our results underscore the urgent need of clinical trials that define the optimal/safest glycemic range in situations of myocardial ischemia.

  3. Cathodic protection of reinforced concrete structures in the Netherlands - Experience and developments: Cathodic protection of concrete - 10 years experience

    NARCIS (Netherlands)

    Polder, R.B.

    1998-01-01

    Cathodic protection (CP) of reinforcing steel in concrete structures has been used successfully for over 20 years. CP is able to stop corrosion in a reliable and economical way where chloride contamination has caused reinforcement corrosion and subsequent concrete damage. To new structures where cor

  4. The Development and Validation of the Protective Factors Survey: A Self-Report Measure of Protective Factors against Child Maltreatment

    Science.gov (United States)

    Counts, Jacqueline M.; Buffington, Elenor S.; Chang-Rios, Karin; Rasmussen, Heather N.; Preacher, Kristopher J.

    2010-01-01

    Objective: The objective of this study was to evaluate the internal structure of a self-report measure of multiple family-level protective factors against abuse and neglect and explore the relationship of this instrument to other measures of child maltreatment. Methods: For the exploratory factor analysis, 11 agencies from 4 states administered…

  5. Cathodic protection of reinforced concrete structures in the Netherlands - Experience and developments: Cathodic protection of concrete - 10 years experience

    NARCIS (Netherlands)

    Polder, R.B.

    1998-01-01

    Cathodic protection (CP) of reinforcing steel in concrete structures has been used successfully for over 20 years. CP is able to stop corrosion in a reliable and economical way where chloride contamination has caused reinforcement corrosion and subsequent concrete damage. To new structures where

  6. THE TRIPS AGREEMENT, INTERNATIONAL TECHNOLOGY TRANSFER AND DEVELOPMENT: SOME LESSONS FROM STRENGTHENING IPR PROTECTION

    Directory of Open Access Journals (Sweden)

    M. Shugurov

    2016-01-01

    Full Text Available The article focuses on the impact of the TRIPS Agreement provisions on further development of international technology transfer (ITT mainly to developing countries. The authors review the critical specificity of ITT connected with the adoption of TRIPS. Much attention is paid to an analysis of what is most discussed among international experts in the area of the issues on the dual results of stronger intellectual property rights (IPRs concerning various groups of developing countries. Their study also examines a number of problems with implementation of the TRIPS provisions, conducive to ITT, in the context of the TRIPS-plus era as a new stage in strengthening IPR protection. Bearing in mind the fragmentation of the international regime of IPR protection because of the adoption of numerous regional free trade agreements, the authors outline the possible position of advanced developing and least developed countries with respect to using TRIPS potentials for development of ITT under reasonable and just terms, with the aim of overall prosperity.

  7. Behavioral adaptation among youth exposed to community violence: a longitudinal multidisciplinary study of family, peer and neighborhood-level protective factors.

    Science.gov (United States)

    Jain, Sonia; Cohen, Alison Klebanoff

    2013-12-01

    Several studies across fields have documented the detrimental effects of exposure to violence and, separately, the power of developmental assets to promote positive youth development. However, few have examined the lives of youth exposed to violence who demonstrate resilience (that is, positive adjustment despite risk), and hardly any have examined how developmental assets may shape resilient trajectories into adulthood for youth exposed to violence. What are these resources and relationships that high-risk youth can leverage to tip the balance from vulnerability in favor of resilience? We used generalized estimating equations to examine multilevel longitudinal data from 1,114 youth of ages 11-16 from the Project on Human Development in Chicago Neighborhoods. Behavioral adaptation was a dynamic process that varied over time and by level of violence exposure. In the short term, being a victim was associated with increased aggression and delinquency. In the long term though, both victims and witnesses to violence had higher odds of behavioral adaptation. Baseline family support and family boundaries, friend support, neighborhood support, and collective efficacy had positive main effects for all youth. Additionally, having family support, positive peers, and meaningful opportunities for participation modified the effect of exposure to violence and increased odds of behavioral adaptation over time. Policies, systems, and programs across sectors should focus on building caring relationships/supports with family members and friends, positive peers, and meaningful opportunities especially for witnesses and victims of violence, to promote behavioral resilience and related outcomes into adulthood for high-risk youth.

  8. Addressing Disaster Risk Management and Adaptation to Climate Change in the Context of Sustainable Development in Africa

    Science.gov (United States)

    Osman Elasha, B. M. E.

    2015-12-01

    The IPCC Special Report on Managing the Risks of Extreme Events and Disasters to Advance Climate Change Adaptation (SREX) demonstrates that an extreme event which used to occur infrequently and perceived today as abnormal will be tomorrow's 'normal' weather. For example the drought events in the African Sahel which once came every decade could now come every couple of years bringing a new challenge and leading to severe disturbances and rapid environmental changes. The report identified and analyzed the problems associated with extreme climatic events, and examined how human responses to these events and the consequent disasters could contribute to adaptation objectives, and how adaptation to climate change could become better integrated with Disasters Risk Management (DRM) practices. Moreover, a number of studies explored the linkages and interactions between disasters and development and clearly demonstrates how the exposure to extremes and vulnerability to climate change can hinder development efforts, emphasizing the need for much smarter development and economic policies that consider managing disaster risk and implement adaptation measures as main components of sustainable development. The proposed presentation will provide an overview of findings from IPCC reports and other studies and will draw on existing experiences and lessons learned to explore the linkages between disaster risk management, adaptation and economic development in Africa. It will also shed light on some of the regional and global interventions which aim at mitigating the impacts of extremes and disasters in African countries characterized by high exposure & vulnerability and low adaptive capacity. It concludes by highlighting the need for broader cooperation and partnership between development partners and agencies working on disaster risk management & climate change adaptation including the private sector, bilateral and multilateral agencies in order to ensure sustainable development.

  9. Development of Nature Protection Technologies of Hydrocarbon Wastes Disposal on the Basis of High- Temperature Pyrolysis

    Science.gov (United States)

    Shantarin, V. D.; Zemenkova, M. Yu; Zemenkov, Yu D.

    2016-10-01

    The research shows the thermal balance of low-temperature pyrolysis of birch sawdust with the possibility of further development of nature protection technology of hydrocarbon wastes disposal with secondary useful products production. The actual problem was solved by preventing environmental pollution by greenhouse gases using pyrolysis process as a method of disposal of hydrocarbon wastes with secondary useful products production. The objective of paper is to study features of the processes of thermal processing of wastes and development of environmentally sound technology of disposal C-containing wastes, contributing to the implementation of the pollution prevention concept.

  10. Sustainable Development and Protection of the Environment: Two Management Strategies Not Always Compatible

    Science.gov (United States)

    Athanassakis, Artemios M.

    2010-01-01

    The definition of Sustainable Development has received intense criticism and contestations with the result, that International Union for the Conservation of Natural Resources (I.U.C.N.), and the World Wide Fund for Nature (W.W.F.) clarified that sustainable development means the improvement of life quality, inside the limits of clarified capacity of ecosystems. According to its critics, is considered as a general concept, indefinite and contradictory. Those disputes put the accent on the close relation between the Sustainable Development and the values of the today's global market. This relationship transforms the Sustainable Development to an one dimensional economical growth with the "ecological ornaments" of sustainability and protection of environment. Therefore this paper looks for, whether the sustainable development consists one more device, focuses on the world financial system, or establishes one optimistic developmental perspective, which might harmonize the economical activities with the natural function of our planetic ecosystems.

  11. Growing adaptive machines combining development and learning in artificial neural networks

    CERN Document Server

    Bredeche, Nicolas; Doursat, René

    2014-01-01

    The pursuit of artificial intelligence has been a highly active domain of research for decades, yielding exciting scientific insights and productive new technologies. In terms of generating intelligence, however, this pursuit has yielded only limited success. This book explores the hypothesis that adaptive growth is a means of moving forward. By emulating the biological process of development, we can incorporate desirable characteristics of natural neural systems into engineered designs, and thus move closer towards the creation of brain-like systems. The particular focus is on how to design artificial neural networks for engineering tasks. The book consists of contributions from 18 researchers, ranging from detailed reviews of recent domains by senior scientists, to exciting new contributions representing the state of the art in machine learning research. The book begins with broad overviews of artificial neurogenesis and bio-inspired machine learning, suitable both as an introduction to the domains and as a...

  12. Difference, adapted physical activity and human development: potential contribution of capabilities approach.

    Science.gov (United States)

    Silva, Carla Filomena; Howe, P David

    2012-01-01

    This paper is a call to Adapted Physical Activity (APA) professionals to increase the reflexive nature of their practice. Drawing upon Foucault's concept of governmentality (1977) APA action may work against its own publicized goals of empowerment and self-determination. To highlight these inconsistencies, we will draw upon historical and social factors that explain the implicit dangers of practice not following policy. We propose that APA practitioners work according to ethical guidelines, based upon a capabilities approach (Nussbaum, 2006, 2011; Sen, 2009) to counteract possible adverse effects of APA practitioner action. A capabilities approach is conducive to the development of each individual's human potential, by holistically considering the consequences of physical activity (i.e., biological, cultural, social, and psychological dimensions). To conclude, this paper will offer suggestions that may lead to an ethical reflection aligned with the best interest of APA's users.

  13. A Two-Stage Combining Classifier Model for the Development of Adaptive Dialog Systems.

    Science.gov (United States)

    Griol, David; Iglesias, José Antonio; Ledezma, Agapito; Sanchis, Araceli

    2016-02-01

    This paper proposes a statistical framework to develop user-adapted spoken dialog systems. The proposed framework integrates two main models. The first model is used to predict the user's intention during the dialog. The second model uses this prediction and the history of dialog up to the current moment to predict the next system response. This prediction is performed with an ensemble-based classifier trained for each of the tasks considered, so that a better selection of the next system can be attained weighting the outputs of these specialized classifiers. The codification of the information and the definition of data structures to store the data supplied by the user throughout the dialog makes the estimation of the models from the training data and practical domains manageable. We describe our proposal and its application and detailed evaluation in a practical spoken dialog system.

  14. On the transferability of three water models developed by adaptive force matching

    CERN Document Server

    Hu, Hongyi; Wang, Feng

    2015-01-01

    Water is perhaps the most simulated liquid. Recently three water models have been developed following the adaptive force matching (AFM) method that provides excellent predictions of water properties with only electronic structure information as a reference. Compared to many other electronic structure based force fields that rely on fairly sophisticated energy expressions, the AFM water models use point-charge based energy expressions that are supported by most popular molecular dynamics packages. An outstanding question regarding simple force fields is whether such force fields provide reasonable transferability outside of their conditions of parameterization. A survey of three AFM water models, B3LYPD-4F, BLYPSP-4F, and WAIL are provided for simulations under conditions ranging from the melting point up to the critical point. By including ice-Ih configurations in the training set, the WAIL potential predicts the melting temperate, TM, of ice-Ih correctly. Without training for ice, BLYPSP-4F underestimates TM...

  15. Recognition of extracellular bacteria by NLRs and its role in the development of adaptive immunity

    Directory of Open Access Journals (Sweden)

    Jonathan eFerrand

    2013-10-01

    Full Text Available Innate immune recognition of bacteria is the first requirement for mounting an effective immune response able to control infection. Over the previous decade, the general paradigm was that extracellular bacteria were only sensed by cell surface-expressed Toll-like receptors (TLRs, whereas cytoplasmic sensors, including members of the Nod-like receptor (NLR family, were specific to pathogens capable of breaching the host cell membrane. It has become apparent, however, that intracellular innate immune molecules, such as the NLRs, play key roles in the sensing of not only intracellular, but also extracellular bacterial pathogens or their components. In this review, we will discuss the various mechanisms used by bacteria to activate NLR signaling in host cells. These mechanisms include bacterial secretion systems, pore-forming toxins and outer membrane vesicles. We will then focus on the influence of NLR activation on the development of adaptive immune responses in different cell types.

  16. Hybrid Adaptive Filter development for the minimisation of transient fluctuations superimposed on electrotelluric field recordings mainly by magnetic storms

    Directory of Open Access Journals (Sweden)

    A. Konstantaras

    2006-01-01

    Full Text Available The method of Hybrid Adaptive Filtering (HAF aims to recover the recorded electric field signals from anomalies of magnetotelluric origin induced mainly by magnetic storms. An adaptive filter incorporating neuro-fuzzy technology has been developed to remove any significant distortions from the equivalent magnetic field signal, as retrieved from the original electric field signal by reversing the magnetotelluric method. Testing with further unseen data verifies the reliability of the model and demonstrates the effectiveness of the HAF method.

  17. Micro-Foundations of Organizational Adaptation : A Field Study in the Evolution of Product Development Capabilities in a Design Firm

    OpenAIRE

    Salvato, Carlo

    2006-01-01

    The aim of this dissertation is to improve knowledge of how organizations adapt to their dynamic environments, by developing a detailed understanding of the configuration and evolution of organizational replicators. Among open questions in the literature on organizational adaptation, I have explored the following: How can the structure of organizational replicators and the nature of their components be realistically described? How do different organizational replicators interact with each oth...

  18. An integrated framework for assessing vulnerability to climate change and developing adaptation strategies for coffee growing families in Mesoamerica

    OpenAIRE

    María Baca; Peter Läderach; Jeremy Haggar; Götz Schroth; Oriana Ovalle

    2014-01-01

    The Mesoamerican region is considered to be one of the areas in the world most vulnerable to climate change. We developed a framework for quantifying the vulnerability of the livelihoods of coffee growers in Mesoamerica at regional and local levels and identify adaptation strategies. Following the Intergovernmental Panel on Climate Change (IPCC) concepts, vulnerability was defined as the combination of exposure, sensitivity and adaptive capacity. To quantify exposure, changes in the climatic ...

  19. Gene Regulation, Alternative Splicing, and Posttranslational Modification of Troponin Subunits in Cardiac Development and Adaptation: A Focused Review

    Directory of Open Access Journals (Sweden)

    Juan-Juan eSheng

    2014-04-01

    Full Text Available Troponin plays a central role in regulating the contraction and relaxation of vertebrate striated muscles. This review focuses on the isoform gene regulation, alternative RNA splicing, and posttranslational modifications of troponin subunits in cardiac development and adaptation. Transcriptional and posttranscriptional regulations such as phosphorylation and proteolysis modifications, and structure-function relationships of troponin subunit proteins are summarized. The physiological and pathophysiological significances are discussed for impacts on cardiac muscle contractility, heart function, and adaptations in health and diseases.

  20. Gene regulation, alternative splicing, and posttranslational modification of troponin subunits in cardiac development and adaptation: a focused review.

    Science.gov (United States)

    Sheng, Juan-Juan; Jin, Jian-Ping

    2014-01-01

    Troponin plays a central role in regulating the contraction and relaxation of vertebrate striated muscles. This review focuses on the isoform gene regulation, alternative RNA splicing, and posttranslational modifications of troponin subunits in cardiac development and adaptation. Transcriptional and posttranscriptional regulations such as phosphorylation and proteolysis modifications, and structure-function relationships of troponin subunit proteins are summarized. The physiological and pathophysiological significances are discussed for impacts on cardiac muscle contractility, heart function, and adaptations in health and diseases.